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Sample records for model produced higher

  1. Higher Order Spreading Models

    CERN Document Server

    Argyros, S A; Tyros, K

    2012-01-01

    We introduce the higher order spreading models associated to a Banach space $X$. Their definition is based on $\\ff$-sequences $(x_s)_{s\\in\\ff}$ with $\\ff$ a regular thin family and the plegma families. We show that the higher order spreading models of a Banach space $X$ form an increasing transfinite hierarchy $(\\mathcal{SM}_\\xi(X))_{\\xi<\\omega_1}$. Each $\\mathcal{SM}_\\xi (X)$ contains all spreading models generated by $\\ff$-sequences $(x_s)_{s\\in\\ff}$ with order of $\\ff$ equal to $\\xi$. We also provide a study of the fundamental properties of the hierarchy.

  2. Nanotechnology combined therapy: tyrosine kinase-bound gold nanorod and laser thermal ablation produce a synergistic higher treatment response of renal cell carcinoma in a murine model.

    Science.gov (United States)

    Liu, James; Abshire, Caleb; Carry, Connor; Sholl, Andrew B; Mandava, Sree Harsha; Datta, Amrita; Ranjan, Manish; Callaghan, Cameron; Peralta, Donna V; Williams, Kristen S; Lai, Weil R; Abdel-Mageed, Asim B; Tarr, Matthew; Lee, Benjamin R

    2017-02-01

    To investigate tyrosine kinase inhibitors (TKI) and gold nanorods (AuNRs) paired with photothermal ablation in a human metastatic clear cell renal cell carcinoma (RCC) mouse model. Nanoparticles have been successful as a platform for targeted drug delivery in the treatment of urological cancers. Likewise, the use of nanoparticles in photothermal tumour ablation, although early in its development, has provided promising results. Our previous in vitro studies of nanoparticles loaded with both TKI and AuNRs and activated with photothermal ablation have shown significant synergistic cell kill greater than each individual arm alone. This study is a translation of our initial findings to an in vivo model. Immunologically naïve nude mice (athymic nude-Foxn1(nu) ) were injected subcutaneously bilaterally in both flanks (n = 36) with 2.5 × 10(6) cells of a human metastatic renal cell carcinoma cell line (RCC 786-O). Subcutaneous xenograft tumours developed into 1-cm palpable nodules. AuNRs encapsulated in human serum albumin protein (HSA) nanoparticles were synthesised with or without a TKI and injected directly into the tumour nodule. Irradiation was administered with an 808-nm light-emitting diode laser for 6 min. Mice were humanely killed 14 days after irradiation; tumours were excised, formalin fixed, paraffin embedded, and evaluated for size and the percentage of necrosis by a genitourinary pathologist. The untreated contralateral flank tumours were used as controls. In mice that did not receive irradiation, TKI alone yielded 4.2% tumour necrosis on the injected side and administration of HSA-AuNR-TKI alone yielded 11.1% necrosis. In the laser-ablation models, laser ablation alone yielded 62% necrosis and when paired with HSA-AuNR there was 63.4% necrosis. The combination of laser irradiation and HSA-AuNR-TKI had cell kill rate of 100%. In the absence of laser irradiation, TKI treatment alone or when delivered via nanoparticles produced moderate necrosis. Irradiation

  3. Higher Education: New Models, New Rules

    Science.gov (United States)

    Soares, Louis; Eaton, Judith S.; Smith, Burck

    2013-01-01

    The Internet enables new models. In the commercial world, for example, we have eBay, Amazon.com, and Netflix. These new models operate with a different set of rules than do traditional models. New models are emerging in higher education as well--for example, competency-based programs. In addition, courses that are being provided from outside the…

  4. Higher Education: New Models, New Rules

    Science.gov (United States)

    Soares, Louis; Eaton, Judith S.; Smith, Burck

    2013-01-01

    The Internet enables new models. In the commercial world, for example, we have eBay, Amazon.com, and Netflix. These new models operate with a different set of rules than do traditional models. New models are emerging in higher education as well--for example, competency-based programs. In addition, courses that are being provided from outside the…

  5. Cosmological Attractor Models and Higher Curvature Supergravity

    CERN Document Server

    Cecotti, Sergio

    2014-01-01

    We study cosmological $\\alpha$-attractors in superconformal/supergravity models, where $\\alpha$ is related to the geometry of the moduli space. For $\\alpha=1$ attractors \\cite{Kallosh:2013hoa} we present a generalization of the previously known manifestly superconformal higher curvature supergravity model \\cite{Cecotti:1987sa}. The relevant standard 2-derivative supergravity with a minimum of two chiral multiplets is shown to be dual to a 4-derivative higher curvature supergravity, where in general one of the chiral superfields is traded for a curvature superfield. There is a degenerate case when both matter superfields become non-dynamical and there is only a chiral curvature superfield, pure higher derivative supergravity. Generic $\\alpha$-models \\cite{Kallosh:2013yoa} interpolate between the attractor point at $\\alpha=0$ and generic chaotic inflation models at large $\\alpha$, in the limit when the inflaton moduli space becomes flat. They have higher derivative duals with the same number of matter fields as...

  6. The Higher Spin/Vector Model Duality

    OpenAIRE

    Giombi, Simone; Yin, Xi

    2012-01-01

    This paper is mainly a review of the dualities between Vasiliev's higher spin gauge theories in AdS4 and three dimensional large N vector models, with focus on the holographic calculation of correlation functions of higher spin currents. We also present some new results in the computation of parity odd structures in the three point functions in parity violating Vasiliev theories.

  7. Monetary Shocks in Models with Inattentive Producers.

    Science.gov (United States)

    Alvarez, Fernando E; Lippi, Francesco; Paciello, Luigi

    2016-04-01

    We study models where prices respond slowly to shocks because firms are rationally inattentive. Producers must pay a cost to observe the determinants of the current profit maximizing price, and hence observe them infrequently. To generate large real effects of monetary shocks in such a model the time between observations must be long and/or highly volatile. Previous work on rational inattentiveness has allowed for observation intervals that are either constant-but-long (e.g. Caballero, 1989 or Reis, 2006) or volatile-but-short (e.g. Reis's, 2006 example where observation costs are negligible), but not both. In these models, the real effects of monetary policy are small for realistic values of the duration between observations. We show that non-negligible observation costs produce both of these effects: intervals between observations are infrequent and volatile. This generates large real effects of monetary policy for realistic values of the average time between observations.

  8. Higher bottomonia in the unquenched quark model

    Directory of Open Access Journals (Sweden)

    Ferretti J.

    2014-06-01

    Full Text Available We show our results for the bottomonium spectrum with self energy corrections, due to the coupling to the meson-meson continuum. We also discuss our results for the open bottom strong decays of higher bottomonia in the 3P0 pair-creation model.

  9. Models for mergers in higher education

    African Journals Online (AJOL)

    Rigor in qualitative research: the assessment of trustworthiness. The ... A possible model for higher education mergers, based on such ... The South African Universities' Vice-Chancellor's Association ..... the drafting of a merger plan and could prevent a joint culture and .... Creating a merger contract that includes. S.

  10. Higher-Dimensional Geometric $\\sigma$-Models

    CERN Document Server

    Vasilic, M

    1999-01-01

    Geometric $\\sigma$-models have been defined as purely geometric theories of scalar fields coupled to gravity. By construction, these theories possess arbitrarily chosen vacuum solutions. Using this fact, one can build a Kaluza--Klein geometric $\\sigma$-model by specifying the vacuum metric of the form $M^4\\times B^d$. The obtained higher dimensional theory has vanishing cosmological constant but fails to give massless gauge fields after the dimensional reduction. In this paper, a modified geometric $\\sigma$-model is suggested, which solves the above problem.

  11. Understanding Higher Education Institutions' Publicness: Do Public Universities Produce More Public Outcomes than Private Universities?

    Science.gov (United States)

    Lee, Young-Joo

    2017-01-01

    Higher education institutions produce a broad array of public outcomes. However, little is known about the varying levels of their contribution to the public good and what explains the variation among institutions. This study uses the theory of organisational publicness and examines how these institutions' ownership status and resource publicness…

  12. Higher-dimensional models of networks

    CERN Document Server

    Spivak, David I

    2009-01-01

    Networks are often studied as graphs, where the vertices stand for entities in the world and the edges stand for connections between them. While relatively easy to study, graphs are often inadequate for modeling real-world situations, especially those that include contexts of more than two entities. For these situations, one typically uses hypergraphs or simplicial complexes. In this paper, we provide a precise framework in which graphs, hypergraphs, simplicial complexes, and many other categories, all of which model higher graphs, can be studied side-by-side. We show how to transform a hypergraph into its nearest simplicial analogue, for example. Our framework includes many new categories as well, such as one that models broadcasting networks. We give several examples and applications of these ideas.

  13. A Higher-Derivative Lee-Wick Standard Model

    CERN Document Server

    Carone, Christopher D

    2009-01-01

    The Lee-Wick Standard Model assumes a minimal set of higher-derivative quadratic terms that produce a negative-norm partner for each Standard Model particle. Here we introduce additional terms of one higher order in the derivative expansion that give each Standard Model particle two Lee-Wick partners: one with negative and one with positive norm. These states collectively cancel unwanted quadratic divergences and resolve the hierarchy problem as in the minimal theory. We show how this next-to-minimal higher-derivative theory may be reformulated via an auxiliary field approach and written as a Lagrangian with interactions of dimension four or less. This mapping provides a convenient framework for studies of the formal and phenomenological properties of the theory.

  14. Higher isolation of NDM-1 producing Acinetobacter baumannii from the sewage of the hospitals in Beijing.

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    Chuanfu Zhang

    Full Text Available Multidrug resistant microbes present in the environment are a potential public health risk. In this study, we investigate the presence of New Delhi metallo-β-lactamase 1 (NDM-1 producing bacteria in the 99 water samples in Beijing City, including river water, treated drinking water, raw water samples from the pools and sewage from 4 comprehensive hospitals. For the bla NDM-1 positive isolate, antimicrobial susceptibility testing was further analyzed, and Pulsed Field Gel Electrophoresis (PFGE was performed to determine the genetic relationship among the NDM-1 producing isolates from sewage and human, as well as the clinical strains without NDM-1. The results indicate that there was a higher isolation of NDM-1 producing Acinetobacter baumannii from the sewage of the hospitals, while no NDM-1 producing isolates were recovered from samples obtained from the river, drinking, or fishpond water. Surprisingly, these isolates were markedly different from the clinical isolates in drug resistance and pulsed field gel electrophoresis profiles, suggesting different evolutionary relationships. Our results showed that the hospital sewage may be one of the diffusion reservoirs of NDM-1 producing bacteria.

  15. Moduli stabilization in higher dimensional brane models

    Energy Technology Data Exchange (ETDEWEB)

    Flachi, Antonino; Pujolas, Oriol [IFAE, Campus UAB, 08193 Bellaterra, Barcelona (Spain)]. E-mail: pujolas@ifae.es; Garriga, Jaume [IFAE, Campus UAB, 08193 Bellaterra, Barcelona (Spain); Departament de Fisica Fonamental and C.E.R. en Astrofisica, Fisica de Particules i Cosmologia Universitat de Barcelona, Marti i Franques 1, 08028 Barcelona (Spain); Tanaka, Takahiro [Institute of Cosmology, Department of Physics and Astronomy, Tufts University, Medford MA 02155 (United States); Yukawa Institute for Theoretical Physics, Kyoto University, Kyoto 606-8502 (Japan)

    2003-08-01

    We consider a class of warped higher dimensional brane models with topology M x {sigma} x S{sup 1}/Z{sub 2}, where {sigma} is a D2 dimensional manifold. Two branes of co-dimension one are embedded in such a bulk space-time and sit at the orbifold fixed points. We concentrate on the case where an exponential warp factor (depending on the distance along the orbifold) accompanies the Minkowski M and the internal space {sigma} line elements. We evaluate the moduli effective potential induced by bulk scalar fields in these models, and we show that generically this can stabilize the size of the extra dimensions. As an application, we consider a scenario where supersymmetry is broken not far below the cutoff scale, and the hierarchy between the electroweak and the effective Planck scales is generated by a combination of redshift and large volume effects. The latter is efficient due to the shrinking of {sigma} at the negative tension brane, where matter is placed. In this case, we find that the effective potential can stabilize the size of the extra dimensions (and the hierarchy) without fine tuning, provided that the internal space {sigma} is flat. (author)

  16. Numerical modeling of higher order magnetic moments in UXO discrimination

    Science.gov (United States)

    Sanchez, V.; Yaoguo, L.; Nabighian, M.N.; Wright, D.L.

    2008-01-01

    The surface magnetic anomaly observed in unexploded ordnance (UXO) clearance is mainly dipolar, and consequently, the dipole is the only magnetic moment regularly recovered in UXO discrimination. The dipole moment contains information about the intensity of magnetization but lacks information about the shape of the target. In contrast, higher order moments, such as quadrupole and octupole, encode asymmetry properties of the magnetization distribution within the buried targets. In order to improve our understanding of magnetization distribution within UXO and non-UXO objects and to show its potential utility in UXO clearance, we present a numerical modeling study of UXO and related metallic objects. The tool for the modeling is a nonlinear integral equation describing magnetization within isolated compact objects of high susceptibility. A solution for magnetization distribution then allows us to compute the magnetic multipole moments of the object, analyze their relationships, and provide a depiction of the anomaly produced by different moments within the object. Our modeling results show the presence of significant higher order moments for more asymmetric objects, and the fields of these higher order moments are well above the noise level of magnetic gradient data. The contribution from higher order moments may provide a practical tool for improved UXO discrimination. ?? 2008 IEEE.

  17. How genetics affects the brain to produce higher-level dysfunctions in myotonic dystrophy type 1.

    Science.gov (United States)

    Serra, Laura; Petrucci, Antonio; Spanò, Barbara; Torso, Mario; Olivito, Giusy; Lispi, Ludovico; Costanzi-Porrini, Sandro; Giulietti, Giovanni; Koch, Giacomo; Giacanelli, Manlio; Caltagirone, Carlo; Cercignani, Mara; Bozzali, Marco

    2015-01-01

    Myotonic dystrophy type 1 (DM1) is a multisystemic disorder dominated by muscular impairment and brain dysfunctions. Although brain damage has previously been demonstrated in DM1, its associations with the genetics and clinical/neuropsychological features of the disease are controversial. This study assessed the differential role of gray matter (GM) and white matter (WM) damage in determining higher-level dysfunctions in DM1. Ten patients with genetically confirmed DM1 and 16 healthy How genetics affects the brain to produce higher-level dysfunctions in myotonic dystrophy type 1 matched controls entered the study. The patients underwent a neuropsychological assessment and quantification of CTG triplet expansion. All the subjects underwent MR scanning at 3T, with studies including T1-weighted volumes and diffusion-weighted images. Voxel-based morphometry and tractbased spatial statistics were used for unbiased quantification of regional GM atrophy and WM integrity. The DM1 patients showed widespread involvement of both tissues. The extent of the damage correlated with CTG triplet expansion and cognition. This study supports the idea that genetic abnormalities in DM1mainly target the WM, but GM involvement is also crucial in determining the clinical characteristics of DM1.

  18. Quantification of Tars, Particulates, and Higher Heating Values in Gases Produced from a Biomass Gasifier

    Directory of Open Access Journals (Sweden)

    Christopher O. Akudo

    2014-07-01

    Full Text Available Syngas from biomass gasifiers contains impurities such as tars and particulates, which can create difficulties for the downstream processes (e.g., internal combustion engines and the Fischer-Tropsch process. To design an efficient and effective gas cleaning system, it is important to accurately quantify the tars and particulates. The absence of an ASTM procedure for tars and particulates produced from a gasifier led to the development and testing of the protocol presented in this study. Syngas was generated from woodchips using a pilot-scale downdraft gasifier, which was designed and constructed in-house. The sampled impurities were analyzed using mass gravimetry, solvent evaporation, and weight differential methods. The higher heating value of the exiting gases was estimated from the syngas composition. The average tar and particulate concentrations of the sample runs were 1.8 to 3.1 g/m3 and 5.2 to 6.4 g/m3, respectively. The higher heating values of the syngas ranged between 4.38 and 4.55 MJ/m3.

  19. Higher-dimensional modelling of geographic information

    NARCIS (Netherlands)

    Arroyo Ohori, G.A.K.

    2016-01-01

    Our world is three-dimensional and complex, continuously changing over time and appearing different at different scales. Yet, when we model it in a computer using Geographic Information Systems (GIS), we mostly use 2D representations, which essentially consist of linked points, lines and polygons. T

  20. Higher Dimensional Generalizations of the SYK Model

    CERN Document Server

    Berkooz, Micha; Rozali, Moshe; Simón, Joan

    2016-01-01

    We discuss a 1+1 dimensional generalization of the Sachdev-Ye-Kitaev model. The model contains $N$ Majorana fermions at each lattice site with a nearest-neighbour hopping term. The SYK random interaction is restricted to low momentum fermions of definite chirality within each lattice site. This gives rise to an ordinary 1+1 field theory above some energy scale and a low energy SYK-like behavior. We exhibit a class of low-pass filters which give rise to a rich variety of hyperscaling behaviour in the IR. We also discuss another set of generalizations which describes probing an SYK system with an external fermion, together with the new scaling behavior they exhibit in the IR.

  1. Splenic Stromal Cells from Aged Mice Produce Higher Levels of IL-6 Compared to Young Mice

    Science.gov (United States)

    Park, Jihyun; Miyakawa, Takuya; Shiokawa, Aya; Nakajima-Adachi, Haruyo; Hachimura, Satoshi

    2014-01-01

    Inflamm-aging indicates the chronic inflammatory state resulting from increased secretion of proinflammatory cytokines and mediators such as IL-6 in the elderly. Our principle objective was to identify cell types that were affected with aging concerning IL-6 secretion in the murine model. We compared IL-6 production in spleen cells from both young and aged mice and isolated several types of cells from spleen and investigated IL-6 mRNA expression and protein production. IL-6 protein productions in cultured stromal cells from aged mice spleen were significantly high compared to young mice upon LPS stimulation. IL-6 mRNA expression level of freshly isolated stromal cells from aged mice was high compared to young mice. Furthermore, stromal cells of aged mice highly expressed IL-6 mRNA after LPS injection in vivo. These results suggest that stromal cells play a role in producing IL-6 in aged mice and imply that they contribute to the chronic inflammatory condition in the elderly. PMID:24729663

  2. Assessment of the Quality Management Models in Higher Education

    Science.gov (United States)

    Basar, Gulsun; Altinay, Zehra; Dagli, Gokmen; Altinay, Fahriye

    2016-01-01

    This study involves the assessment of the quality management models in Higher Education by explaining the importance of quality in higher education and by examining the higher education quality assurance system practices in other countries. The qualitative study was carried out with the members of the Higher Education Planning, Evaluation,…

  3. Dynamics in Higher Education Politics: A Theoretical Model

    Science.gov (United States)

    Kauko, Jaakko

    2013-01-01

    This article presents a model for analysing dynamics in higher education politics (DHEP). Theoretically the model draws on the conceptual history of political contingency, agenda-setting theories and previous research on higher education dynamics. According to the model, socio-historical complexity can best be analysed along two dimensions: the…

  4. Maternal effects on male weaponry: female dung beetles produce major sons with longer horns when they perceive higher population density

    Directory of Open Access Journals (Sweden)

    Buzatto Bruno A

    2012-07-01

    Full Text Available Abstract Background Maternal effects are environmental influences on the phenotype of one individual that are due to the expression of genes in its mother, and are expected to evolve whenever females are better capable of assessing the environmental conditions that their offspring will experience than the offspring themselves. In the dung beetle Onthophagus taurus, conditional male dimorphism is associated with alternative reproductive tactics: majors fight and guard females whereas minors sneak copulations. Furthermore, variation in dung beetle population density has different fitness consequences for each male morph, and theory predicts that higher population density might select for a higher frequency of minors and/or greater expenditure on weaponry in majors. Because adult dung beetles provide offspring with all the nutritional resources for their development, maternal effects strongly influence male phenotype. Results Here we tested whether female O. taurus are capable of perceiving population density, and responding by changing the phenotype of their offspring. We found that mothers who were reared with other conspecifics in their pre-mating period produced major offspring that had longer horns across a wider range of body sizes than the major offspring of females that were reared in isolation in their pre-mating period. Moreover, our results indicate that this maternal effect on male weaponry does not operate through the amount of dung provided by females to their offspring, but is rather transmitted through egg or brood mass composition. Finally, although theory predicts that females experiencing higher density might produce more minor males, we found no support for this, rather the best fitting models were equivocal as to whether fewer or the same proportions of minors were produced. Conclusions Our study describes a new type of maternal effect in dung beetles, which probably allows females to respond to population density adaptively

  5. Writing disciplines: producing disciplinary knowledge in the context of contemporary higher education

    Directory of Open Access Journals (Sweden)

    Karin Tusting

    2016-11-01

    Full Text Available This paper addresses academic disciplinary writing practices, and how these are affected by changes in the landscape of Higher Education in the UK. After exploring the definition and understanding of the notion of “discipline”, the paper presents research from an ESRC-funded research project studying academics’ everyday writing practices, working closely with academics across different disciplines and different kinds of higher education institutions. The changing context of Higher Education in the UK is presented, in particular the emergence of new kinds of managerial practices which shape and co-ordinate the everyday writing work of academics. The paper shows that while some disciplines, such as History and Pure Mathematics, are associated with clearly-defined writing practices, others are more diverse. It discusses how managerial practices, particularly those driven by centralised national research evaluations, affect different disciplines in different ways.

  6. How to produce flat slabs: insights from numeric modeling

    Science.gov (United States)

    Constantin Manea, Vlad; Perez-Gussinye, Marta; Manea, Marina

    2010-05-01

    Flat slab subduction occurs at ~10% of the active convergent margins and it is assumed that subduction of oceanic aseismic ridges or seamount chains is the main mechanism to produce very low angle subduction slabs. However, recent numeric and analog modeling showed that ridges alone of moderate dimensions subducted perpendicular to the trench are not sufficient to produce flat-slab geometries. Therefore an alternative mechanism able to produce flat-slabs is required. In this paper we present dynamic numeric modeling results of subduction in the vicinity of thick continental lithosphere, as a craton for example. We tailored our modeling setup for the Chilean margins at ~31° and our models are integrated back in time 30 Myr. Modeling results show that a craton thickness of 200 km or more when approaching the trench is capable of blocking the asthenospheric flow in the mantle wedge and increasing considerably the suction force. We were able to produce a flat slab that fits well the flat slab geometry in Chile (based on seismicity) and stress distribution. We conclude that thick cratons located in the vicinity of subduction zones, are capable to produce very low angle slabs, and probable a combination of buoyant ridge subduction with a neighbor thick craton represent a better mechanism to produce flat slabs.

  7. Higher Education Quality Assessment Model: Towards Achieving Educational Quality Standard

    Science.gov (United States)

    Noaman, Amin Y.; Ragab, Abdul Hamid M.; Madbouly, Ayman I.; Khedra, Ahmed M.; Fayoumi, Ayman G.

    2017-01-01

    This paper presents a developed higher education quality assessment model (HEQAM) that can be applied for enhancement of university services. This is because there is no universal unified quality standard model that can be used to assess the quality criteria of higher education institutes. The analytical hierarchy process is used to identify the…

  8. Higher Education Quality Assessment Model: Towards Achieving Educational Quality Standard

    Science.gov (United States)

    Noaman, Amin Y.; Ragab, Abdul Hamid M.; Madbouly, Ayman I.; Khedra, Ahmed M.; Fayoumi, Ayman G.

    2017-01-01

    This paper presents a developed higher education quality assessment model (HEQAM) that can be applied for enhancement of university services. This is because there is no universal unified quality standard model that can be used to assess the quality criteria of higher education institutes. The analytical hierarchy process is used to identify the…

  9. Video Editing and Medication to Produce a Therapeutic Self Model

    Science.gov (United States)

    Dowrick, Peter W.; Raeburn, John M.

    1977-01-01

    Self-modeling requires the production of a videotape in which the subject is seen to perform in a model way. A 4-year-old "hyperactive" boy, initially under psychotropic medication, was unable to role play suitable behaviors. Video editing was used to produce a videotape that when watched by the subject, had therapeutic effects as compared with an…

  10. Stochastic Models for Phylogenetic Trees on Higher-order Taxa

    CERN Document Server

    Aldous, David; Popovic, Lea

    2007-01-01

    Simple stochastic models for phylogenetic trees on species have been well studied. But much paleontology data concerns time series or trees on higher-order taxa, and any broad picture of relationships between extant groups requires use of higher-order taxa. A coherent model for trees on (say) genera should involve both a species-level model and a model for the classification scheme by which species are assigned to genera. We present a general framework for such models, and describe three alternate classification schemes. Combining with the species-level model of Aldous-Popovic (2005), one gets models for higher-order trees, and we initiate analytic study of such models. In particular we derive formulas for the lifetime of genera, for the distribution of number of species per genus, and for the offspring structure of the tree on genera.

  11. Transcendent innovations produced in higher education in Argentina during the 1946-1955 period

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    Gabriela Mirta Ocampo

    2013-11-01

    Full Text Available The government period 1946-1955 can be considered one of the periods of greatest innovations regarding university education in Argentina. This was achieved, on the one hand, through the laws that were passed which transformed the current higher education system, and on the other one, through the founding of the “Universidad Obrera Nacional” which brought about a new concept of higher education that was much more in keeping with the requirements of modern industry. This is why it is indispensable to deeply analyze the law N ° 13031 which established a very meticulous system for the functioning and organization of the national universities in replacement of the law N ° 1597 that had been current for more than sixty years. The same goes for the law N ° 14297 that adapted the aforementioned law to the National Constitution of 1949 and for the law N ° 13229 that created the “Universidad Obrera Nacional”, origin of the current “Universidad Tecnológica Nacional”. This work develops a deep insight of this process.

  12. Producing a Set of Models for the Iron Homeostasis Network

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    Nicolas Mobilia

    2013-08-01

    Full Text Available This paper presents a method for modeling biological systems which combines formal techniques on intervals, numerical simulations and satisfaction of Signal Temporal Logic (STL formulas. The main modeling challenge addressed by this approach is the large uncertainty in the values of the parameters due to the experimental difficulties of getting accurate biological data. This method considers intervals for each parameter and a formal description of the expected behavior of the model. In a first step, it produces reduced intervals of possible parameter values. Then by performing a systematic search in these intervals, it defines sets of parameter values used in the next step. This procedure aims at finding a sub-space where the model robustly behaves as expected. We apply this method to the modeling of the cellular iron homeostasis network in erythroid progenitors. The produced model describes explicitly the regulation mechanism which acts at the translational level.

  13. Modeling of higher order systems using artificial bee colony algorithm

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    Aytekin Bağış

    2016-05-01

    Full Text Available In this work, modeling of the higher order systems based on the use of the artificial bee colony (ABC algorithm were examined. Proposed model parameters for the sample systems in the literature were obtained by using the algorithm, and its performance was presented comparatively with the other methods. Simulation results show that the ABC algorithm based system modeling approach can be used as an efficient and powerful method for higher order systems.

  14. Dual equivalence in models with higher-order derivatives

    CERN Document Server

    Bazeia, D; Nascimento, J R S; Ribeiro, R F; Wotzasek, C

    2003-01-01

    We introduce a class of higher-order derivative models in (2,1) space-time dimensions. The models are described by a vector field, and contain a Proca-like mass term which prevents gauge invariance. We use the gauge embedding procedure to generate another class of higher-order derivative models, gauge-invariant and dual to the former class. We also show that the gauge embedding approach works appropriately when the vector field couples with fermionic matter.

  15. Cellulase-producing bacteria from Thai higher termites, Microcerotermes sp.: enzymatic activities and ionic liquid tolerance.

    Science.gov (United States)

    Taechapoempol, Kitipong; Sreethawong, Thammanoon; Rangsunvigit, Pramoch; Namprohm, Weerachart; Thamprajamchit, Bandhit; Rengpipat, Sirirat; Chavadej, Sumaeth

    2011-05-01

    The three highest hydrolysis-capacity-value isolates of Bacillus subtilis (A 002, M 015, and F 018) obtained from Thai higher termites, Microcerotermes sp., under different isolation conditions (aerobic, anaerobic, and anaerobic/aerobic) were tested for cellulase activities--FPase, endoglucanase, and β-glucosidase--at 37 °C and pH 7.2 for 24 h. Their tolerance to an ionic liquid, 1-butyl-3-methylimidazolium chloride ([BMIM]Cl), was also investigated. The results showed that the isolate M 015 provided the highest endoglucanase activity whereas the highest FPase and β-glucosidase activities were observed for the isolate F 018. The isolate F 018 also showed the highest tolerance to [BMIM]Cl in the range of 0.1-1.0 vol.%. In contrast, the isolate A 002 exhibited growth retardation in the presence of 0.5-1.0 vol.% [BMIM]Cl.

  16. Data Producers Courting Data Reusers: Two Cases from Modeling Communities

    Directory of Open Access Journals (Sweden)

    Jillian Wallis

    2014-07-01

    Full Text Available Data sharing is a difficult process for both the data producer and the data reuser. Both parties are faced with more disincentives than incentives. Data producers need to sink time and resources into adding metadata for data to be findable and usable, and there is no promise of receiving credit for this effort. Making data available also leaves data producers vulnerable to being scooped or data misuse. Data reusers also need to sink time and resources into evaluating data and trying to understand them, making collecting their own data a more attractive option. In spite of these difficulties, some data producers are looking for new ways to make data sharing and reuse a more viable option. This paper presents two cases from the surface and climate modeling communities, where researchers who produce data are reaching out to other researchers who would be interested in reusing the data. These cases are evaluated as a strategy to identify ways to overcome the challenges typically experienced by both data producers and data reusers. By working together with reusers, data producers are able to mitigate the disincentives and create incentives for sharing data. By working with data producers, data reusers are able to circumvent the hurdles that make data reuse so challenging.

  17. How genetics affects the brain to produce higher-level dysfunctions in myotonic dystrophy type 1

    Science.gov (United States)

    Serra, Laura; Petrucci, Antonio; Spanò, Barbara; Torso, Mario; Olivito, Giusy; Lispi, Ludovico; Costanzi-Porrini, Sandro; Giulietti, Giovanni; Koch, Giacomo; Giacanelli, Manlio; Caltagirone, Carlo; Cercignani, Mara; Bozzali, Marco

    2015-01-01

    Summary Myotonic dystrophy type 1 (DM1) is a multisystemic disorder dominated by muscular impairment and brain dysfunctions. Although brain damage has previously been demonstrated in DM1, its associations with the genetics and clinical/neuropsychological features of the disease are controversial. This study assessed the differential role of gray matter (GM) and white matter (WM) damage in determining higher-level dysfunctions in DM1. Ten patients with genetically confirmed DM1 and 16 healthy matched controls entered the study. The patients underwent a neuropsychological assessment and quantification of CTG triplet expansion. All the subjects underwent MR scanning at 3T, with studies including T1-weighted volumes and diffusion-weighted images. Voxel-based morphometry and tract-based spatial statistics were used for unbiased quantification of regional GM atrophy and WM integrity. The DM1 patients showed widespread involvement of both tissues. The extent of the damage correlated with CTG triplet expansion and cognition. This study supports the idea that genetic abnormalities in DM1 mainly target the WM, but GM involvement is also crucial in determining the clinical characteristics of DM1. PMID:26214024

  18. Building Higher-Order Markov Chain Models with EXCEL

    Science.gov (United States)

    Ching, Wai-Ki; Fung, Eric S.; Ng, Michael K.

    2004-01-01

    Categorical data sequences occur in many applications such as forecasting, data mining and bioinformatics. In this note, we present higher-order Markov chain models for modelling categorical data sequences with an efficient algorithm for solving the model parameters. The algorithm can be implemented easily in a Microsoft EXCEL worksheet. We give a…

  19. Educational Retrenchment: A Model for Institutions of Higher Education.

    Science.gov (United States)

    Ishler, Richard E.

    1981-01-01

    Due to economic factors, many institutions of higher education may be forced to reduce faculty positions. The procedures used by Emporia State University (Kansas) can be used as a model for colleges needing to pursue various methods of retrenchment. (JN)

  20. AN INSTRUCTIONAL DESIGN MODEL FOR BLENDED HIGHER EDUCATION

    Directory of Open Access Journals (Sweden)

    George Hack

    2016-07-01

    Full Text Available Instructional design models that are used by many higher education institutions to guide course design are insufficient for the unique opportunities of blended learning. Many established models are not practical tools for college faculty to use independently in the design of courses. Models like A.D.D.I.E., use a linear approach that can translate more easily into practical stages of course design, yet are historically rooted in the rapid prototyping of educational technologies or for designing military training and are inadequate for the complex demands of higher education, where learning outcomes are geared toward higher order thinking, scientific/clinical reasoning, and a syntheses of ideas into new knowledge. Presented here is an instructional design model that strategically incorporates the nuances of higher education, yet is practically framed to assist faculty with design challenges.

  1. Guiding and Modelling Quality Improvement in Higher Education Institutions

    Science.gov (United States)

    Little, Daniel

    2015-01-01

    The article considers the process of creating quality improvement in higher education institutions from the point of view of current organisational theory and social-science modelling techniques. The author considers the higher education institution as a functioning complex of rules, norms and other organisational features and reviews the social…

  2. Exploring Higher Education Business Models ("If Such a Thing Exists")

    Science.gov (United States)

    Harney, John O.

    2013-01-01

    The global economic recession has caused students, parents, and policymakers to reevaluate personal and societal investments in higher education--and has prompted the realization that traditional higher ed "business models" may be unsustainable. Predicting a shakeout, most presidents expressed confidence for their own school's ability to…

  3. Guiding and Modelling Quality Improvement in Higher Education Institutions

    Science.gov (United States)

    Little, Daniel

    2015-01-01

    The article considers the process of creating quality improvement in higher education institutions from the point of view of current organisational theory and social-science modelling techniques. The author considers the higher education institution as a functioning complex of rules, norms and other organisational features and reviews the social…

  4. Exploring Higher Education Business Models ("If Such a Thing Exists")

    Science.gov (United States)

    Harney, John O.

    2013-01-01

    The global economic recession has caused students, parents, and policymakers to reevaluate personal and societal investments in higher education--and has prompted the realization that traditional higher ed "business models" may be unsustainable. Predicting a shakeout, most presidents expressed confidence for their own school's ability to…

  5. Large field inflation models from higher-dimensional gauge theories

    Science.gov (United States)

    Furuuchi, Kazuyuki; Koyama, Yoji

    2015-02-01

    Motivated by the recent detection of B-mode polarization of CMB by BICEP2 which is possibly of primordial origin, we study large field inflation models which can be obtained from higher-dimensional gauge theories. The constraints from CMB observations on the gauge theory parameters are given, and their naturalness are discussed. Among the models analyzed, Dante's Inferno model turns out to be the most preferred model in this framework.

  6. Large field inflation models from higher-dimensional gauge theories

    Energy Technology Data Exchange (ETDEWEB)

    Furuuchi, Kazuyuki [Manipal Centre for Natural Sciences, Manipal University, Manipal, Karnataka 576104 (India); Koyama, Yoji [Department of Physics, National Tsing-Hua University, Hsinchu 30013, Taiwan R.O.C. (China)

    2015-02-23

    Motivated by the recent detection of B-mode polarization of CMB by BICEP2 which is possibly of primordial origin, we study large field inflation models which can be obtained from higher-dimensional gauge theories. The constraints from CMB observations on the gauge theory parameters are given, and their naturalness are discussed. Among the models analyzed, Dante’s Inferno model turns out to be the most preferred model in this framework.

  7. Modeling Human Behaviour with Higher Order Logic: Insider Threats

    DEFF Research Database (Denmark)

    Boender, Jaap; Ivanova, Marieta Georgieva; Kammuller, Florian

    2014-01-01

    In this paper, we approach the problem of modeling the human component in technical systems with a view on the difference between the use of model and theory in sociology and computer science. One aim of this essay is to show that building of theories and models for sociology can be compared...... it to the sociological process of logical explanation. As a case study on modeling human behaviour, we present the modeling and analysis of insider threats as a Higher Order Logic theory in Isabelle/HOL. We show how each of the three step process of sociological explanation can be seen in our modeling of insider’s state...

  8. Modelling in Evaluating a Working Life Project in Higher Education

    Science.gov (United States)

    Sarja, Anneli; Janhonen, Sirpa; Havukainen, Pirjo; Vesterinen, Anne

    2012-01-01

    This article describes an evaluation method based on collaboration between the higher education, a care home and university, in a R&D project. The aim of the project was to elaborate modelling as a tool of developmental evaluation for innovation and competence in project cooperation. The approach was based on activity theory. Modelling enabled a…

  9. A CONCEPTUAL MODEL FOR EFFECTIVE DISTANCE LEARNING IN HIGHER A CONCEPTUAL MODEL FOR EFFECTIVE DISTANCE LEARNING IN HIGHER A CONCEPTUAL MODEL FOR EFFECTIVE DISTANCE LEARNING IN HIGHER EDUCATION

    Directory of Open Access Journals (Sweden)

    Mehran FARAJOLLAHI

    2010-07-01

    Full Text Available The present research aims at presenting a conceptual model for effective distance learning in higher education. Findings of this research shows that an understanding of the technological capabilities and learning theories especially constructive theory and independent learning theory and communicative and interaction theory in Distance learning is an efficient factor in the planning of effective Distance learning in higher education. Considering the theoretical foundations of the present research, in the effective distance learning model, the learner is situated at the center of learning environment. For this purpose, the learner needs to be ready for successful learning and the teacher has to be ready to design the teaching- learning activities when they initially enter the environment. In the present model, group and individual active teaching-learning approach, timely feedback, using IT and eight types of interactions have been designed with respect to theoretical foundations and current university missions. From among the issues emphasized in this model, one can refer to the Initial, Formative and Summative evaluations. In an effective distance learning environment, evaluation should be part of the learning process and the feedback resulting from it should be used to improve learning. For validating the specified features, the opinions of Distance learning experts in Payame Noor, Shiraz, Science and Technology and Amirkabir Universities have been used which verified a high percentage of the statistical sample of the above mentioned features.

  10. An entrepreneurial education model for the Namibian Higher Education system

    Directory of Open Access Journals (Sweden)

    P. Ras

    2007-12-01

    Full Text Available Purpose: The aim of this paper is to develop an entrepreneurial education model for implementation in the Namibian Higher Education system. Namibia, just like South Africa, has an objective to develop small, medium and micro enterprises to enhance economic growth and reduce unemployment. Development of such a model is supported by the government of Namibia. This paper investigates appropriate entrepreneurial education models used in South Africa for this purpose.Design/Methodology/Approach: This research is an exploratory research design based upon secondary data mainly provided by the Namibian Economic Policy Research Unit (NEPRU that enabled the researcher to understand and identify the problems that Namibia encounter in their small business environment. Theories, as developed by the University of Pretoria based on entrepreneurial education, were explored and formed the base of the theory exploration. Findings : The researcher investigated an existing entrepreneurial education model being used for the South African context, as well as a comparison of two models, and an integrated model based on the cited models. These models are used to show the importance of such models and the need to develop one for Namibia. Implications: This paper presents a model that can solve the basic need expressed by the Namibian Higher Education System to find an appropriate model to implement. Originality/Value: This paper provides a foundation from which an entrepreneurial education model can be implemented and improved / customised for the Namibian context.

  11. Higher-Rank Supersymmetric Models and Topological Field Theory

    CERN Document Server

    Kawai, T; Yang, S K; Kawai, Toshiya; Uchino, Taku; Yang, Sung-Kil

    1993-01-01

    In the first part of this paper we investigate the operator aspect of higher-rank supersymmetric model which is introduced as a Lie theoretic extension of the $N=2$ minimal model with the simplest case $su(2)$ corresponding to the $N=2$ minimal model. In particular we identify the analogs of chirality conditions and chiral ring. In the second part we construct a class of topological conformal field theories starting with this higher-rank supersymmetric model. We show the BRST-exactness of the twisted stress-energy tensor, find out physical observables and discuss how to make their correlation functions. It is emphasized that in the case of $su(2)$ the topological field theory constructed in this paper is distinct from the one obtained by twisting the $N=2$ minimal model through the usual procedure.

  12. Modelling of interference pattern produced by Michelson interferometer

    Science.gov (United States)

    Glebov, Victor; Lashmanov, Oleg

    2016-04-01

    Using of Michelson interferometer is shown in the field of measurement of periodical displacements of the con-trolled object. The foundations of optical interferometry are presented. The features of Michelson interferometer are described. The mathematical model of interference pattern produced by Michelson interferometer is created. It takes in consideration such parameters as the angles at which the mirrors are located and the lengths of two optical paths.

  13. Agent Based Model of Young Researchers in Higher Education Institutions

    Directory of Open Access Journals (Sweden)

    Josip Stepanic

    2013-04-01

    Full Text Available Group of young researchers in higher education institutions in general perform demandable tasks with relatively high contribution to institutions’ and societies’ innovation production. In order to analyse in more details interaction among young researchers and diverse institutions in society, we aim toward developing the numerical simulation, agent-based model.This article presents foundations of the model, preliminary results of its simulation along with perspectives of its further development and improvements.

  14. Covariant 4-dimensional fuzzy spheres, matrix models and higher spin

    Science.gov (United States)

    Sperling, Marcus; Steinacker, Harold C.

    2017-09-01

    We study in detail generalized 4-dimensional fuzzy spheres with twisted extra dimensions. These spheres can be viewed as SO(5) -equivariant projections of quantized coadjoint orbits of SO(6) . We show that they arise as solutions in Yang-Mills matrix models, which naturally leads to higher-spin gauge theories on S 4. Several types of embeddings in matrix models are found, including one with self-intersecting fuzzy extra dimensions \

  15. Low-spin models for higher-spin Lagrangians

    CERN Document Server

    Francia, Dario

    2011-01-01

    Higher-spin theories are most commonly modelled on the example of spin 2. While this is appropriate for the description of free irreducible spin-s particles, alternative options could be equally interesting. In particular Maxwell's equations provide the effective model for maximally reducible theories of higher spins inspired by the tensionless limit of the open string. For both options, as well as for their fermionic counterparts, one can extend the analogy beyond the equations for the gauge potentials, formulating the corresponding Lagrangians in terms of higher-spin curvatures. The associated non-localities are effectively due to the elimination of auxiliary fields and do not modify the spectrum. Massive deformations of these theories are also possible, and in particular in this contribution we propose a generalisation of the Proca Lagrangian for the Maxwell-inspired geometric theories.

  16. A Structural Equation Model for ICT Usage in Higher Education

    Science.gov (United States)

    Usluel, Yasemin Kocak; Askar, Petek; Bas, Turgay

    2008-01-01

    This study focuses on Information and Communication Technologies (ICT) usage, which is the indicator of diffusion. A model composed of the variables which can explain ICT usage in Turkish higher education is established and tested within the study. The two dimensions of ICT usage are considered: instructional and managerial. The data collected…

  17. Higher-Order Item Response Models for Hierarchical Latent Traits

    Science.gov (United States)

    Huang, Hung-Yu; Wang, Wen-Chung; Chen, Po-Hsi; Su, Chi-Ming

    2013-01-01

    Many latent traits in the human sciences have a hierarchical structure. This study aimed to develop a new class of higher order item response theory models for hierarchical latent traits that are flexible in accommodating both dichotomous and polytomous items, to estimate both item and person parameters jointly, to allow users to specify…

  18. A Conceptual Model for Effective Distance Learning in Higher Education

    Science.gov (United States)

    Farajollahi, Mehran; Zare, Hosein; Hormozi, Mahmood; Sarmadi, Mohammad Reza; Zarifsanaee, Nahid

    2010-01-01

    The present research aims at presenting a conceptual model for effective distance learning in higher education. Findings of this research shows that an understanding of the technological capabilities and learning theories especially constructive theory and independent learning theory and communicative and interaction theory in Distance learning is…

  19. Anodic biofilms in microbial fuel cells harbor low numbers of higher-power-producing bacteria than abundant genera

    Energy Technology Data Exchange (ETDEWEB)

    Kiely, Patrick D.; Call, Douglas F.; Yates, Matthew D.; Regan, John M.; Logan, Bruce E. [Pennsylvania State Univ., University Park, PA (United States). Dept. of Civil and Environmental Engineering

    2010-09-15

    Microbial fuel cell (MFC) anode communities often reveal just a few genera, but it is not known to what extent less abundant bacteria could be important for improving performance. We examined the microbial community in an MFC fed with formic acid for more than 1 year and determined using 16S rRNA gene cloning and fluorescent in situ hybridization that members of the Paracoccus genus comprised most ({proportional_to}30%) of the anode community. A Paracoccus isolate obtained from this biofilm (Paracoccus denitrificans strain PS-1) produced only 5.6 mW/m{sup 2}, whereas the original mixed culture produced up to 10 mW/m{sup 2}. Despite the absence of any Shewanella species in the clone library, we isolated a strain of Shewanella putrefaciens (strain PS-2) from the same biofilm capable of producing a higher-power density (17.4 mW/m{sup 2}) than the mixed culture, although voltage generation was variable. Our results suggest that the numerical abundance of microorganisms in biofilms cannot be assumed a priori to correlate to capacities of these predominant species for high-power production. Detailed screening of bacterial biofilms may therefore be needed to identify important strains capable of high-power generation for specific substrates. (orig.)

  20. Anodic biofilms in microbial fuel cells harbor low numbers of higher-power-producing bacteria than abundant genera

    KAUST Repository

    Kiely, Patrick D.

    2010-07-15

    Microbial fuel cell (MFC) anode communities often reveal just a few genera, but it is not known to what extent less abundant bacteria could be important for improving performance. We examined the microbial community in an MFC fed with formic acid for more than 1 year and determined using 16S rRNA gene cloning and fluorescent in situ hybridization that members of the Paracoccus genus comprised most (~30%) of the anode community. A Paracoccus isolate obtained from this biofilm (Paracoccus denitrificans strain PS-1) produced only 5.6 mW/m 2, whereas the original mixed culture produced up to 10 mW/m 2. Despite the absence of any Shewanella species in the clone library, we isolated a strain of Shewanella putrefaciens (strain PS-2) from the same biofilm capable of producing a higher-power density (17.4 mW/m2) than the mixed culture, although voltage generation was variable. Our results suggest that the numerical abundance of microorganisms in biofilms cannot be assumed a priori to correlate to capacities of these predominant species for high-power production. Detailed screening of bacterial biofilms may therefore be needed to identify important strains capable of high-power generation for specific substrates. © 2010 Springer-Verlag.

  1. Transducer model produces facilitation from opposite-sign flanks

    Science.gov (United States)

    Solomon, J. A.; Watson, A. B.; Morgan, M. J.

    1999-01-01

    Small spots, lines and Gabor patterns can be easier to detect when they are superimposed upon similar spots, lines and Gabor patterns. Traditionally, such facilitation has been understood to be a consequence of nonlinear contrast transduction. Facilitation has also been reported to arise from non-overlapping patterns with opposite sign. We point out that this result does not preclude the traditional explanation for superimposed targets. Moreover, we find that facilitation from opposite-sign flanks is weaker than facilitation from same-sign flanks. Simulations with a transducer model produce opposite-sign facilitation.

  2. Icodextrin produces higher ultrafiltration in diabetic than in non-diabetic patients on continuous cyclic peritoneal dialysis.

    Science.gov (United States)

    Ahmad, Mufazzal; Jeloka, Tarun; Pliakogiannis, Theodoros; Tapiawala, Shruti; Zhong, Hui; Bargman, Joanne M; Oreopoulos, Dimitrios

    2008-01-01

    A preliminary report from our unit previously suggested that diabetic patients on continuous cyclic peritoneal dialysis (CCPD) have higher ultrafiltration (UF) with icodextrin than non-diabetic patients. To confirm this observation, we did a retrospective analysis of our patients (17 diabetic and 23 non-diabetic) who were on stable CCPD prescription using a long-day dwell with icodextrin. We collected daily UF data from these patients' records for 30 days. The two groups showed no significant difference with respect to age, gender, hemoglobin, serum albumin, peritoneal dialysis and icodextrin vintage, peritoneal membrane characteristics, CCPD prescription, and peritoneal and residual renal clearance. The overnight net UF achieved with the cycler with standard glucose dialysate was similar in the two groups (850+/-379 in diabetic vs 713+/-484 ml/day in non-diabetic, P=0.34). However, UF with icodextrin during the day dwell (14.8+/-0.8 h) was significantly higher in diabetics than non-diabetics (348+/-198 vs 137+/-311 ml/day, P=0.02). Our results show that icodextrin produces significantly higher UF in long-day dwell in diabetic ESRD patients on CCPD than in non-diabetic patients. The reason for this difference is not clear.

  3. Massive fermion model in 3d and higher spin currents

    CERN Document Server

    Bonora, L; Prester, P Dominis; de Souza, B Lima; Smolic, I

    2016-01-01

    We analyze the 3d free massive fermion theory coupled to external sources. The presence of a mass explicitly breaks parity invariance. We calculate two- and three-point functions of a gauge current and the energy momentum tensor and, for instance, obtain the well-known result that in the IR limit (but also in the UV one) we reconstruct the relevant CS action. We then couple the model to higher spin currents and explicitly work out the spin 3 case. In the UV limit we obtain an effective action which was proposed many years ago as a possible generalization of spin 3 CS action. In the IR limit we derive a different higher spin action. This analysis can evidently be generalized to higher spins. We also discuss the conservation and properties of the correlators we obtain in the intermediate steps of our derivation.

  4. Higher-dimensional Higgs Representations in SGUT models

    CERN Document Server

    Aranda, Alfredo; Rojas, Alma D

    2010-01-01

    Supersymmetric Grand Unified Theories (SGUTs) have achieved some degree of success, already present in the minimal models (with SU(5) or SO(10)). However, there are open problems that suggest the need to incorporate more elaborate constructions, specifically the use of higher-dimensional representations in the Higgs sector. For example, a $45$ representation of SU(5) is often included to obtain correct mass relations for the first and second families of d-type quarks and leptons. When one adds these higher-dimensional Higgs representations one must verify the cancellation of anomalies associated to their fermionic partners. One possible choice, free of anomalies, include both $45,\\overline{45}$ representations to cancel anomalies. We review the necessary conditions for the cancellation of anomalies and discuss the different possibilities for supersymmetric SU(5) models. Alternative anomaly-free combinations of Higgs representations, beyond the usual vectorlike choice, are identified, and it is shown that thei...

  5. Modeling the Competence Acquiring Process in Higher Education Institution

    DEFF Research Database (Denmark)

    Malinowska, Magdelena; Kusztina, Emma; Zaikin, Oleg

    2013-01-01

    Changes in human capital management, new requirements regarding knowledge and skills of employees compel higher education institutions to redefine their learning programmes. This requires evaluation of the didactic process realization, which should be oriented on competences. In the article authors...... presents an approach to competence modeling. New tools and collaboration mechanisms are proposed, which allow defining the structure of competence, analyzing the level of competence development, and assessing the competence process realization in relation “expected benefit-required expense”....

  6. Modeling the Competence Acquiring Process in Higher Education Institution

    DEFF Research Database (Denmark)

    Malinowska, Magdelena; Kusztina, Emma; Zaikin, Oleg

    2013-01-01

    Changes in human capital management, new requirements regarding knowledge and skills of employees compel higher education institutions to redefine their learning programmes. This requires evaluation of the didactic process realization, which should be oriented on competences. In the article authors...... presents an approach to competence modeling. New tools and collaboration mechanisms are proposed, which allow defining the structure of competence, analyzing the level of competence development, and assessing the competence process realization in relation “expected benefit-required expense”....

  7. Higher-order factors of the big five model of personality: a reanalysis of Digman (1997).

    Science.gov (United States)

    Mutch, Christopher

    2005-02-01

    Based on the results from factor analyses conducted on 14 different data sets, Digman proposed a model of two higher-order factors, or metatraits, that subsumed the Big Five personality traits. In the current article, problems in Digman's analyses were explicated, and more appropriate analyses were then conducted using the same 14 correlation matrices from Digman's study. The resultant two-factor model produced improper solutions, poor model fit indices, or both, in almost all of the 14 data sets and thus raised serious doubts about the veracity of Digman's proposed model.

  8. Modeling terrestrial gamma ray flashes produced by relativistic feedback discharges

    Science.gov (United States)

    Liu, Ningyu; Dwyer, Joseph R.

    2013-05-01

    This paper reports a modeling study of terrestrial gamma ray flashes (TGFs) produced by relativistic feedback discharges. Terrestrial gamma ray flashes are intense energetic radiation originating from the Earth's atmosphere that has been observed by spacecraft. They are produced by bremsstrahlung interactions of energetic electrons, known as runaway electrons, with air atoms. An efficient physical mechanism for producing large fluxes of the runaway electrons to make the TGFs is the relativistic feedback discharge, where seed runaway electrons are generated by positrons and X-rays, products of the discharge itself. Once the relativistic feedback discharge becomes self-sustaining, an exponentially increasing number of relativistic electron avalanches propagate through the same high-field region inside the thundercloud until the electric field is partially discharged by the ionization created by the discharge. The modeling results indicate that the durations of the TGF pulses produced by the relativistic feedback discharge vary from tens of microseconds to several milliseconds, encompassing all durations of the TGFs observed so far. In addition, when a sufficiently large potential difference is available in thunderclouds, a self-propagating discharge known as the relativistic feedback streamer can be formed, which propagates like a conventional positive streamer. For the relativistic feedback streamer, the positive feedback mechanism of runaway electron production by the positrons and X-rays plays a similar role as the photoionization for the conventional positive streamer. The simulation results of the relativistic feedback streamer show that a sequence of TGF pulses with varying durations can be produced by the streamer. The relativistic streamer may initially propagate with a pulsed manner and turn into a continuous propagation mode at a later stage. Milliseconds long TGF pulses can be produced by the feedback streamer during its continuous propagation. However

  9. Analytical Higher-Order Model for Flexible and Stretchable Sensors

    Institute of Scientific and Technical Information of China (English)

    ZHANG Yongfang; ZHU Hongbin; LIU Cheng; LIU Xu; LIU Fuxi; L Yanjun

    2015-01-01

    The stretchable sensor wrapped around a foldable airfoil or embedded inside of it has great potential for use in the monitoring of the structural status of the foldable airfoil. The design methodology is important to the development of the stretchable sensor for status monitoring on the foldable airfoil. According to the requirement of mechanical flexibility of the sensor, the combined use of a layered flexible structural formation and a strain isolation layer is implemented. An analytical higher-order model is proposed to predict the stresses of the strain-isolation layer based on the shear-lag model for the safe design of the flexible and stretchable sensors. The normal stress and shear stress equations in the constructed structure of the sensors are obtained by the proposed model. The stress distribution in the structure is investigated when bending load is applied to the structures. The numerical results show that the proposed model can predict the variation of normal stress and shear stress along the thickness of the strain-isolation (polydimethylsiloxane) layer accurately. The results by the proposed model are in good agreement with the finite element method, in which the normal stress is variable while the shear stress is invariable along the thickness direction of strain-isolation layer. The high-order model is proposed to predict the stresses of the layered structure of the flexible and stretchable sensor for monitoring the status of the foldable airfoil.

  10. MATURITY MODEL FOR IT SERVICE OUTSOURCING IN HIGHER EDUCATION INSTITUTIONS

    Directory of Open Access Journals (Sweden)

    Victoriano Valencia García

    2013-11-01

    Full Text Available The current success of organizations depends on the successful implementation of Information and Comunication Technologies (ICTs. Good governance and ICT management are essential for delivering value, managing technological risks, managing resources and performance measurement. In addition, outsourcing is a strategic option which complements IT services provided internally in organizations. This paper proposes the design of a new holistic maturity model based on standards ISO/IEC 20000 and ISO/IEC 38500, the frameworks and best practices of ITIL and COBIT, with a specific focus on IT outsourcing. This model is validated by practices in the field of higher education, using a questionnaire and a metrics table among other measurement tools. Models, standards and guidelines are proposed in the model for facilitating adaptation to universities and achieving excellence in the outsourcing of IT services. The applicability of the model allows an effective transition to a model of good governance and management of outsourced IT services which, aligned with the core business of universities (teaching, research and innovation, affect the effectiveness and efficiency of its management, optimizes its value and minimizes risks.

  11. A Global Change in Higher Education: Entrepreneurial University Model

    Directory of Open Access Journals (Sweden)

    Süreyya SAKINÇ

    2012-01-01

    Full Text Available Universities are affected by the social and economic diversity stemmed from globalization and internationalization, and its functions, area of responsibility, organizational structure, funding capability respond this diversity. In today's knowledge society, different new concepts regarding the university education system such as Entrepreneur University, Corporation University, virtual university etc. have been emerged with wave of globalization effect. The rising competition in academic education and the mass demands for education prompt to universities to get seeking new funds for fixing their financial situation, and hit them transforming into entrepreneurial identity. The reflections of neoliberal approach in education have transformed the universities into the corporations which are much more focused on entrepreneurial, student-oriented and aimed to appropriate education and producing creative human resources for global development. In this study, a comprehensive evaluation will be carried on regarding the entrepreneur university model through the litterateur research to investigate its causes and factors that impact and improve it. The aim of the paper is to generate a framework that identifies dynamic processes of entrepreneur university model, dependently the litterateur syntheses. The contribution of the paper will depend on its consequent argument that entrepreneur university model is viable for Turkey. In this paper, the entrepreneur university model will be analyzed by Triple Helix phenomenon with the comparative approach.

  12. Integrable Cosmological Models From Higher Dimensional Einstein Equations

    CERN Document Server

    Sano, M; Sano, Masakazu; Suzuki, Hisao

    2007-01-01

    We consider the cosmological models for the higher dimensional spacetime which includes the curvatures of our space as well as the curvatures of the internal space. We find that the condition for the integrability of the cosmological equations is that the total space-time dimensions are D=10 or D=11 which is exactly the conditions for superstrings or M-theory. We obtain analytic solutions with generic initial conditions in the four dimensional Einstein frame and study the accelerating universe when both our space and the internal space have negative curvatures.

  13. L∞-algebra models and higher Chern-Simons theories

    Science.gov (United States)

    Ritter, Patricia; Sämann, Christian

    2016-10-01

    We continue our study of zero-dimensional field theories in which the fields take values in a strong homotopy Lie algebra. In the first part, we review in detail how higher Chern-Simons theories arise in the AKSZ-formalism. These theories form a universal starting point for the construction of L∞-algebra models. We then show how to describe superconformal field theories and how to perform dimensional reductions in this context. In the second part, we demonstrate that Nambu-Poisson and multisymplectic manifolds are closely related via their Heisenberg algebras. As a byproduct of our discussion, we find central Lie p-algebra extensions of 𝔰𝔬(p + 2). Finally, we study a number of L∞-algebra models which are physically interesting and which exhibit quantized multisymplectic manifolds as vacuum solutions.

  14. The microchannel flow model under shear stress and higher frequencies.

    Science.gov (United States)

    Parker, Kevin J

    2017-02-24

    The microchannel flow model provides a framework for considering the effect of the vascular bed on the time domain and frequency domain response of soft tissues. The derivation originates with a single small fluid filled vessel in an elastic medium under uniaxial compression. A fractal branching vasculature is also assumed to be present in the tissue under consideration. This short technical note considers two closely related issues. First, the response of the element under compression or shear as a function of the orientation of the fluid-filled vessel is considered. Second, the transition from quasistatic (Poiseuille's Law) to dynamic (Womersley equations) fluid flow is examined to better predict the evolution of behavior at higher frequencies. These considerations expand the conceptual framework of the microchannel flow model, particularly the range and limits of validity.

  15. The microchannel flow model under shear stress and higher frequencies

    Science.gov (United States)

    Parker, K. J.

    2017-04-01

    The microchannel flow model provides a framework for considering the effect of the vascular bed on the time domain and frequency domain response of soft tissues. The derivation originates with a single small fluid-filled vessel in an elastic medium under uniaxial compression. A fractal branching vasculature is also assumed to be present in the tissue under consideration. This note considers two closely related issues. First, the response of the element under compression or shear as a function of the orientation of the fluid-filled vessel is considered. Second, the transition from quasistatic (Poiseuille’s Law) to dynamic (Womersley equations) fluid flow is examined to better predict the evolution of behavior at higher frequencies. These considerations expand the conceptual framework of the microchannel flow model, particularly the range and limits of validity.

  16. Wave Transformation Modeling with Effective Higher-Order Finite Elements

    Directory of Open Access Journals (Sweden)

    Tae-Hwa Jung

    2016-01-01

    Full Text Available This study introduces a finite element method using a higher-order interpolation function for effective simulations of wave transformation. Finite element methods with a higher-order interpolation function usually employ a Lagrangian interpolation function that gives accurate solutions with a lesser number of elements compared to lower order interpolation function. At the same time, it takes a lot of time to get a solution because the size of the local matrix increases resulting in the increase of band width of a global matrix as the order of the interpolation function increases. Mass lumping can reduce computation time by making the local matrix a diagonal form. However, the efficiency is not satisfactory because it requires more elements to get results. In this study, the Legendre cardinal interpolation function, a modified Lagrangian interpolation function, is used for efficient calculation. Diagonal matrix generation by applying direct numerical integration to the Legendre cardinal interpolation function like conducting mass lumping can reduce calculation time with favorable accuracy. Numerical simulations of regular, irregular and solitary waves using the Boussinesq equations through applying the interpolation approaches are carried out to compare the higher-order finite element models on wave transformation and examine the efficiency of calculation.

  17. Experimental Verification of Modeled Thermal Distribution Produced by a Piston Source in Physiotherapy Ultrasound

    Directory of Open Access Journals (Sweden)

    M. I. Gutierrez

    2016-01-01

    Full Text Available Objectives. To present a quantitative comparison of thermal patterns produced by the piston-in-a-baffle approach with those generated by a physiotherapy ultrasonic device and to show the dependency among thermal patterns and acoustic intensity distributions. Methods. The finite element (FE method was used to model an ideal acoustic field and the produced thermal pattern to be compared with the experimental acoustic and temperature distributions produced by a real ultrasonic applicator. A thermal model using the measured acoustic profile as input is also presented for comparison. Temperature measurements were carried out with thermocouples inserted in muscle phantom. The insertion place of thermocouples was monitored with ultrasound imaging. Results. Modeled and measured thermal profiles were compared within the first 10 cm of depth. The ideal acoustic field did not adequately represent the measured field having different temperature profiles (errors 10% to 20%. Experimental field was concentrated near the transducer producing a region with higher temperatures, while the modeled ideal temperature was linearly distributed along the depth. The error was reduced to 7% when introducing the measured acoustic field as the input variable in the FE temperature modeling. Conclusions. Temperature distributions are strongly related to the acoustic field distributions.

  18. Experimental Verification of Modeled Thermal Distribution Produced by a Piston Source in Physiotherapy Ultrasound

    Science.gov (United States)

    Lopez-Haro, S. A.; Leija, L.

    2016-01-01

    Objectives. To present a quantitative comparison of thermal patterns produced by the piston-in-a-baffle approach with those generated by a physiotherapy ultrasonic device and to show the dependency among thermal patterns and acoustic intensity distributions. Methods. The finite element (FE) method was used to model an ideal acoustic field and the produced thermal pattern to be compared with the experimental acoustic and temperature distributions produced by a real ultrasonic applicator. A thermal model using the measured acoustic profile as input is also presented for comparison. Temperature measurements were carried out with thermocouples inserted in muscle phantom. The insertion place of thermocouples was monitored with ultrasound imaging. Results. Modeled and measured thermal profiles were compared within the first 10 cm of depth. The ideal acoustic field did not adequately represent the measured field having different temperature profiles (errors 10% to 20%). Experimental field was concentrated near the transducer producing a region with higher temperatures, while the modeled ideal temperature was linearly distributed along the depth. The error was reduced to 7% when introducing the measured acoustic field as the input variable in the FE temperature modeling. Conclusions. Temperature distributions are strongly related to the acoustic field distributions. PMID:27999801

  19. Poland, assuring and strengthening the quality of (private) higher education : One of twelve case studies produced as part of the project on structural reform in higher education

    NARCIS (Netherlands)

    Kwiek, Marek; Antonowicz, Dominik; Westerheijden, Donald F.

    2016-01-01

    This study analyses how different types of system-level (or ‘landscape’) structural reforms in higher education have been designed and implemented in selected higher education systems. In the 12 case studies that form the core of the project, the researchers examine reforms aimed at:• Increasing

  20. France, initiatives for excellence in higher education: One of twelve case studies produced as part of the project on structural reform in higher education

    NARCIS (Netherlands)

    Boudard, Emmanuel; Westerheijden, Don F.

    2016-01-01

    This study analyses how different types of system-level (or ‘landscape’) structural reforms in higher education have been designed and implemented in selected higher education systems. In the 12 case studies that form the core of the project, the researchers examine reforms aimed at:• Increasing hor

  1. Higher plant modelling for life support applications: first results of a simple mechanistic model

    Science.gov (United States)

    Hezard, Pauline; Dussap, Claude-Gilles; Sasidharan L, Swathy

    2012-07-01

    In the case of closed ecological life support systems, the air and water regeneration and food production are performed using microorganisms and higher plants. Wheat, rice, soybean, lettuce, tomato or other types of eatable annual plants produce fresh food while recycling CO2 into breathable oxygen. Additionally, they evaporate a large quantity of water, which can be condensed and used as potable water. This shows that recycling functions of air revitalization and food production are completely linked. Consequently, the control of a growth chamber for higher plant production has to be performed with efficient mechanistic models, in order to ensure a realistic prediction of plant behaviour, water and gas recycling whatever the environmental conditions. Purely mechanistic models of plant production in controlled environments are not available yet. This is the reason why new models must be developed and validated. This work concerns the design and test of a simplified version of a mathematical model coupling plant architecture and mass balance purposes in order to compare its results with available data of lettuce grown in closed and controlled chambers. The carbon exchange rate, water absorption and evaporation rate, biomass fresh weight as well as leaf surface are modelled and compared with available data. The model consists of four modules. The first one evaluates plant architecture, like total leaf surface, leaf area index and stem length data. The second one calculates the rate of matter and energy exchange depending on architectural and environmental data: light absorption in the canopy, CO2 uptake or release, water uptake and evapotranspiration. The third module evaluates which of the previous rates is limiting overall biomass growth; and the last one calculates biomass growth rate depending on matter exchange rates, using a global stoichiometric equation. All these rates are a set of differential equations, which are integrated with time in order to provide

  2. Investigating Effective Components of Higher Education Marketing and Providing a Marketing Model for Iranian Private Higher Education Institutions

    Science.gov (United States)

    Kasmaee, Roya Babaee; Nadi, Mohammad Ali; Shahtalebi, Badri

    2016-01-01

    Purpose: The purpose of this paper is to study and identify the effective components of higher education marketing and providing a marketing model for Iranian higher education private sector institutions. Design/methodology/approach: This study is a qualitative research. For identifying the effective components of higher education marketing and…

  3. Development of Saccharomyces cerevisiae producing higher levels of sulfur dioxide and glutathione to improve beer flavor stability.

    Science.gov (United States)

    Chen, Yefu; Yang, Xu; Zhang, Shijie; Wang, Xiaoqiong; Guo, Changhui; Guo, Xuewu; Xiao, Dongguang

    2012-01-01

    Sulfur compounds, such as sulfite (SO(2)), hydrogen sulfide (H(2)S), and glutathione (GSH), play different roles in beer flavor stability. SO(2) and GSH have antiaging effects which are helpful to improve the flavor stability of beer, whereas H(2)S is undesirable to beer flavor because of its unpleasant aroma. Here, we report the development of Saccharomyces cerevisiae which produces higher levels of SO(2) and GSH but lower level of H(2)S to improve beer flavor stability by nongenetic engineering approaches. After two rounds of UV mutagenesis coupled with specific plate screening methods, one promising mutant named MV16 was obtained. Compared with the original strain, the SO(2) and GSH production of MV16 in fermenting liquor increased by 31% and 30.2%, respectively, while H(2)S content decreased by 74.9%, and the DPPH radical clearance and the resistance staling value of beer fermented by MV16 increased by 24.6% and 33.0%, respectively. The antioxidizability of the mutant was improved significantly. The strategy adopted in our study could be used to obtain S. cerevisiae of improved antiaging properties, and the mutant would be safe for public use.

  4. Higher Rank ABJM Wilson Loops from Matrix Models

    Science.gov (United States)

    Cookmeyer, Jonathan; Liu, James; Zayas, Leopoldo

    2017-01-01

    We compute the expectation values of 1/6 supersymmetric Wilson Loops in ABJM theory in higher rank representations. Using standard matrix model techniques, we calculate the expectation value in the rank m fully symmetric and fully antisymmetric representation where m is scaled with N. To leading order, we find agreement with the classical action of D6 and D2 branes in AdS4 ×CP3 respectively. Further, we compute the first subleading order term, which, on the AdS side, makes a prediction for the one-loop effective action of the corresponding D6 and D2 branes. Supported by the National Science Foundation under Grant No. PHY 1559988 and the US Department of Energy under Grant No. DE-SC0007859.

  5. Inflationary scenarios in Starobinsky model with higher order corrections

    Energy Technology Data Exchange (ETDEWEB)

    Artymowski, Michał [Institute of Physics, Jagiellonian University,Łojasiewicza 11, 30-348 Kraków (Poland); Lalak, Zygmunt [Institute of Theoretical Physics, Faculty of Physics, University of Warsaw,ul. Pasteura 5, 02-093 Warsaw (Poland); Lewicki, Marek [Institute of Theoretical Physics, Faculty of Physics, University of Warsaw,ul. Pasteura 5, 02-093 Warsaw (Poland); Michigan Center for Theoretical Physics, University of Michigan,450 Church Street, Ann Arbor MI 48109 (United States)

    2015-06-17

    We consider the Starobinsky inflation with a set of higher order corrections parametrised by two real coefficients λ{sub 1} ,λ{sub 2}. In the Einstein frame we have found a potential with the Starobinsky plateau, steep slope and possibly with an additional minimum, local maximum or a saddle point. We have identified three types of inflationary behaviour that may be generated in this model: i) inflation on the plateau, ii) at the local maximum (topological inflation), iii) at the saddle point. We have found limits on parameters λ{sub i} and initial conditions at the Planck scale which enable successful inflation and disable eternal inflation at the plateau. We have checked that the local minimum away from the GR vacuum is stable and that the field cannot leave it neither via quantum tunnelling nor via thermal corrections.

  6. Declarative XML Update Language Based on a Higher Data Model

    Institute of Scientific and Technical Information of China (English)

    Guo-Ren Wang; Xiao-Lin Zhang

    2005-01-01

    With the extensive use of XML in applications over the Web, how to update XML data is becoming an important issue because the role of XML has expanded beyond traditional applications in which XML is used for information exchange and data representation over the Web. So far, several languages have been proposed for updating XML data, but they are all based on lower, so-called graph-based or tree-based data models. Update requests are thus expressed in a nonintuitive and unnatural way and update statements are too complicated to comprehend. This paper presents a novel declarative XML update language which is an extension of the XML-RL query language. Compared with other existing XML update languages, it has the following features. First, it is the only XML data manipulation language based on a higher data model. Second, this language can express complex update requests at multiple levels in a hierarchy in a simple and flat way. Third, this language directly supports the functionality of updating complex objects while all other update languages do not support these operations. Lastly, most of existing languages use rename to modify attribute and element names, which is a different way from updates on value. The proposed language modifies tag names, values, and objects in a unified way by the introduction of three kinds of logical binding variables: object variables, value variables, and name variables.

  7. BF models, duality and bosonization in higher genus surfaces

    CERN Document Server

    Restuccia, A

    2000-01-01

    We consider two dimensional field theories of the $BF$ type written in terms of aglobally defined 1-form $A$ and a multivalued scalar field $B$ with a lagrangian function given by $L=dB{\\wedge}A$. In order to have the model globally defined on compact Riemann surfaces of arbitrary genus one has to provide certain conditions on the periods of $dB$ . We analyze the generating functional of these models coupled to fermionic fields and show that they have a non-trivial dependence on the topological restrictions imposed to the $B$ field. It is shown in particular that when the periods of the $B$field are constrained to take the values $4{\\pi}n$ with $n$ any integer number,the partition function is independent of the chosen spin structure and may be written as a sum over all the spin structures associated to the fermions even when one starts with a fixed spin structure. These results are then applied to the functional bosonization of the fermion fields in higher genus surfaces. A bosonized form of the partition fun...

  8. Higher derivative massive spin-3 models in D =2 +1

    Science.gov (United States)

    Dalmazi, D.; Mendonça, E. L.

    2016-07-01

    We find new higher derivative models describing a parity doublet of massive spin-3 modes in D =2 +1 dimensions. One of them is of fourth order in derivatives while the other one is of sixth order. They are complete, in the sense that they contain the auxiliary scalar field required to remove spurious degrees of freedom. Both of them are obtained through the master action technique starting with the usual (second-order) spin-3 Singh-Hagen model, which guarantees that they are ghost free. The fourth- and sixth-order terms are both invariant under (transverse) Weyl transformations, quite similarly to the fourth-order K -term of the "new massive gravity." The sixth-order term slightly differs from the product of the Schouten by the Einstein tensor, both of third order in derivatives. It is also possible to write down the fourth-order term as a product of a Schouten-like by an Einstein-like tensor (both of second order in derivatives) in close analogy with the K -term.

  9. Mouse model of sustained elevation in intraocular pressure produced by episcleral vein occlusion.

    Science.gov (United States)

    Ruiz-Ederra, Javier; Verkman, A S

    2006-05-01

    We have developed an inducible mouse model of glaucoma based on episcleral vein cauterization (EVC). Intraocular pressure (IOP) elevation in adult mice was produced by cauterizing three episcleral veins. Serial IOP measurements were done by induction-impact tonometry. IOP was significantly elevated by 104+/-20% in 20 out of 23 mice (87%) within the first day after EVC, and remained elevated for 4 weeks, with mean IOP 94% higher in EVC-treated vs. contralateral control eyes. Aqueous outflow blockade was verified from the IOP response to pulsed fluid infusions into the anterior chamber. Retinal ganglion cell (RGC) loss, determined by retrograde labelling using Fluoro-Gold applied to the superior colliculous, was approximately 20% at 2 weeks after EVC. We conclude that episcleral vein occlusion in mice produces significant and sustained elevation in IOP associated with increased outflow resistance and RGC loss, and thus may be useful to model glaucoma in genetically modified and drug-treated mice.

  10. Comparison of dimensional accuracy of digital dental models produced from scanned impressions and scanned stone casts

    Science.gov (United States)

    Subeihi, Haitham

    dimensional accuracy, which is defined as the absolute value of deviation in micrometers from the reference model. A two-way analysis of analysis of variance (ANOVA) was applied to calculate if the measurements for the six test groups were statistically significantly different from the original reference model as well as between test groups (p Tukey's HSD was also applied to characterize the differences. Results: The mean (± SD) RMS was 29.42 ± 5.80 microns for digital models produced from polyether impression scans, 27.58 ± 5.85 microns for digital models from PVS impressions scans, and 24.08 ± 4.89 microns for digital models produced from VPES impressions scans. 26.08 ± 6.58 microns for digital models produced by scanning stone casts poured from PE, 31.67 ± 9.95 microns for digital models produced by scanning stone casts poured from PVS and 22.58 ± 2.84 microns for digital models produced by scanning stone casts poured from VPES. In the Two-Way ANOVA, the p-value for the material factor was 0.004, reflecting a statistically significant difference between the accuracy of the three impression materials, with VPES showing the highest accuracy (mean RMS = 23.33 ± 3.99 microns) followed by PE (mean RMS = 27.75 ± 6.3 microns) and PVS (mean RMS = 29.63 ± 8.25 microns). For the technique factor, the p-value was 0.870 reflecting no statistically significant difference between the accuracy of the two techniques (impression scan and stone cast scan). The mean RMS values were 27.03 ± 5.82 microns and 26.78 ± 7.85 microns, respectively. In the post-hoc tests for the material factor, a significant difference was found between the accuracy of VPES and PVS (p-value = 0.004) with VPES having the higher accuracy (lower mean RMS). No significant difference was found between the accuracies of PE and PVS (p-value = 0.576), and between the accuracies of PE and VPES (p-value = 0.054). Conclusions: Within the limitations of this in vitro study, it can be concluded that: 1. There is no

  11. Market-Based Higher Education: Does Colorado's Voucher Model Improve Higher Education Access and Efficiency?

    Science.gov (United States)

    Hillman, Nicholas W.; Tandberg, David A.; Gross, Jacob P. K.

    2014-01-01

    In 2004, Colorado introduced the nation's first voucher model for financing public higher education. With state appropriations now allocated to students, rather than institutions, state officials expect this model to create cost efficiencies while also expanding college access. Using difference-in-difference regression analysis, we find…

  12. A Distributed Leadership Change Process Model for Higher Education

    Science.gov (United States)

    Jones, Sandra; Harvey, Marina

    2017-01-01

    The higher education sector operates in an increasingly complex global environment that is placing it under considerable stress and resulting in widespread change to the operating context and leadership of higher education institutions. The outcome has been the increased likelihood of conflict between academics and senior leaders, presaging the…

  13. A MODEL FOR HIGHER EDUCATION CAMPUS HEALTH SERVICES

    African Journals Online (AJOL)

    2010-03-17

    Mar 17, 2010 ... nurses who are employed at a higher education campus' health service to render a healthcare ..... effectively perform roles and tasks expected of him or her in .... all times by those with whom the individual comes into contact.

  14. A MODEL FOR HIGHER EDUCATION CAMPUS HEALTH SERVICES

    African Journals Online (AJOL)

    2010-03-17

    Mar 17, 2010 ... nurses who are employed at a higher education campus' health service to render a healthcare ..... extremely diverse in terms of gender, age, religion, culture, .... the environment, with relative freedom from pain, disability,.

  15. A Review on the Models of Organizational Effectiveness: A Look at Cameron's Model in Higher Education

    Science.gov (United States)

    Ashraf, Giti; Kadir, Suhaida bte Abd

    2012-01-01

    Organizational effectiveness is the main concern of all higher education institutes. Over the years there have been many different models of effectiveness along with the criteria for measuring organizational effectiveness. In this paper, four main models of organizational effectiveness namely the goal approach, the system resource approach, the…

  16. Business Model Innovation: A Blueprint for Higher Education

    Science.gov (United States)

    Flanagan, Christine

    2012-01-01

    Business model innovation is one of the most challenging components of 21st-century leadership. Making incremental improvements to a business model--creating new efficiencies, expanding into adjacent markets--is hard enough. Developing and experimenting with new business models that truly transform how an institution delivers value (while…

  17. Modeling Human Behaviour with Higher Order Logic: Insider Threats

    NARCIS (Netherlands)

    Boender, Jaap; Ivanova, Marieta Georgieva; Kammüller, Florian; Primierio, Giuseppe

    2014-01-01

    In this paper, we approach the problem of modeling the human component in technical systems with a view on the difference between the use of model and theory in sociology and computer science. One aim of this essay is to show that building of theories and models for sociology can be compared and imp

  18. Business Model Innovation: A Blueprint for Higher Education

    Science.gov (United States)

    Flanagan, Christine

    2012-01-01

    Business model innovation is one of the most challenging components of 21st-century leadership. Making incremental improvements to a business model--creating new efficiencies, expanding into adjacent markets--is hard enough. Developing and experimenting with new business models that truly transform how an institution delivers value (while…

  19. Developing a Model for Simplified Higher Level Sensor Fusion

    Science.gov (United States)

    2013-01-01

    conveying its wide scope is to use a process model. The most referenced model within the DoD appears to be the Joint Director of Labs ( JDL ) data fusion...model shown in Figure 1 [5]. The JDL , is an organization which no longer exists but in the 1980s they were tasked to develop a model for data fu- sion...This JDL model, revised in 1999, was created to show a general process of data fusion with wide applicability for both government and academia. It

  20. Towards a Computational Model of a Methane Producing Archaeum

    Directory of Open Access Journals (Sweden)

    Joseph R. Peterson

    2014-01-01

    Full Text Available Progress towards a complete model of the methanogenic archaeum Methanosarcina acetivorans is reported. We characterized size distribution of the cells using differential interference contrast microscopy, finding them to be ellipsoidal with mean length and width of 2.9 μm and 2.3 μm, respectively, when grown on methanol and 30% smaller when grown on acetate. We used the single molecule pull down (SiMPull technique to measure average copy number of the Mcr complex and ribosomes. A kinetic model for the methanogenesis pathways based on biochemical studies and recent metabolic reconstructions for several related methanogens is presented. In this model, 26 reactions in the methanogenesis pathways are coupled to a cell mass production reaction that updates enzyme concentrations. RNA expression data (RNA-seq measured for cell cultures grown on acetate and methanol is used to estimate relative protein production per mole of ATP consumed. The model captures the experimentally observed methane production rates for cells growing on methanol and is most sensitive to the number of methyl-coenzyme-M reductase (Mcr and methyl-tetrahydromethanopterin:coenzyme-M methyltransferase (Mtr proteins. A draft transcriptional regulation network based on known interactions is proposed which we intend to integrate with the kinetic model to allow dynamic regulation.

  1. Modeling and computation of mean field equilibria in producers' game with emission permits trading

    Science.gov (United States)

    Zhang, Shuhua; Wang, Xinyu; Shanain, Aleksandr

    2016-08-01

    In this paper, we present a mean field game to model the production behaviors of a very large number of producers, whose carbon emissions are regulated by government. Especially, an emission permits trading scheme is considered in our model, in which each enterprise can trade its own permits flexibly. By means of the mean field equilibrium, we obtain a Hamilton-Jacobi-Bellman (HJB) equation coupled with a Kolmogorov equation, which are satisfied by the adjoint state and the density of producers (agents), respectively. Then, we propose a so-called fitted finite volume method to solve the HJB equation and the Kolmogorov equation. The efficiency and the usefulness of this method are illustrated by the numerical experiments. Under different conditions, the equilibrium states as well as the effects of the emission permits price are examined, which demonstrates that the emission permits trading scheme influences the producers' behaviors, that is, more populations would like to choose a lower rather than a higher emission level when the emission permits are expensive.

  2. The Whole Shebang: How Science Produced the Big Bang Model.

    Science.gov (United States)

    Ferris, Timothy

    2002-01-01

    Offers an account of the accumulation of evidence that has led scientists to have confidence in the big bang theory of the creation of the universe. Discusses the early work of Ptolemy, Copernicus, Kepler, Galileo, and Newton, noting the rise of astrophysics, and highlighting the birth of the big bang model (the cosmic microwave background theory…

  3. Creating, implementing, and validating a virtual learning model in web 2.0 technologies for higher education.

    OpenAIRE

    Zambrano, William Ricardo; Pontificia Universidad Javeriana; Medina, Victor Hugo; Universidad Pontificia de Salamanca

    2010-01-01

    In this article we examine different world educational models supported on Information Technologies (ITs) and their impact, in order to produce a Virtual Learning Model in Web 2.0 Technologies for Higher education in Colombia. We resorted to applied and theoretical, qualitative and quantitative research methods covered by an area usually known as descriptive and co-relational studies. The Model was implemented and then validated in two academic courses. The method basically comprised activiti...

  4. Design of Higher Education Teaching Models and Carbon Impacts

    Science.gov (United States)

    Caird, Sally; Lane, Andy; Swithenby, Ed; Roy, Robin; Potter, Stephen

    2015-01-01

    Purpose: This research aims to examine the main findings of the SusTEACH study of the carbon-based environmental impacts of 30 higher education (HE) courses in 15 UK institutions, based on an analysis of the likely energy consumption and carbon emissions of a range of face-to-face, distance, online and information and communication technology…

  5. Exploring Business Models for MOOCS in Higher Education

    Science.gov (United States)

    Burd, Elizabeth L.; Smith, Shamus P.; Reisman, Sorel

    2015-01-01

    Massive Open Online Courses (MOOCs) potentially challenge the traditional dominance of brick and mortar institutions as providers of quality higher education. The benefits for students include reduced education costs and global access to exclusive institution courses and instructors. However, the benefits for institutions are less clear as there…

  6. Modeling Antecedents of Student Loyalty in Higher Education

    Science.gov (United States)

    Perin, Marcelo Gattermann; Sampaio, Claudio Hoffmann; Simoes, Claudia; de Polvora, Rosiane Polvora

    2012-01-01

    The purpose of this investigation is to understand the antecedents of student loyalty in the Brazilian context. In particular we address the impact of student trust, commitment and quality perception on loyalty. A quantitative study was conducted among business management student majors from two private Brazilian Higher Education Institutions…

  7. Exploring Business Models for MOOCS in Higher Education

    Science.gov (United States)

    Burd, Elizabeth L.; Smith, Shamus P.; Reisman, Sorel

    2015-01-01

    Massive Open Online Courses (MOOCs) potentially challenge the traditional dominance of brick and mortar institutions as providers of quality higher education. The benefits for students include reduced education costs and global access to exclusive institution courses and instructors. However, the benefits for institutions are less clear as there…

  8. Modeling Antecedents of Student Loyalty in Higher Education

    Science.gov (United States)

    Perin, Marcelo Gattermann; Sampaio, Claudio Hoffmann; Simoes, Claudia; de Polvora, Rosiane Polvora

    2012-01-01

    The purpose of this investigation is to understand the antecedents of student loyalty in the Brazilian context. In particular we address the impact of student trust, commitment and quality perception on loyalty. A quantitative study was conducted among business management student majors from two private Brazilian Higher Education Institutions…

  9. The behavior and pathological changes characteristic to Alzheimer's disease produced by higher concentration zinc in cerebrospinal fluid

    Institute of Scientific and Technical Information of China (English)

    Li Lin; Wu Jianliang Jin Zhang Zhihua; Hao JunWei; Cheng Yanqiu

    2003-01-01

    The aim of this work was to estimate the behavior and pathological changes characteristic to Alzheimer' s disease(AD)inducedby local higher concentration of zinc in brain in rats. ZnC12 was infused into cerebral ventricle. Behavioral tests were performed in the Morris Wa-ter Maze( MWM). The apoptotic cells were tested by flow cytometry. Immuncytochemical staining was used to show expression of beta - amyloidprotein( Aβ). Pathological changes at cellular level were examined under transmission electron microscope(TEM). There was significant behaviordamage in zinc treated animals. There were more apoptosis in zinc treated animals. Fawn - coloured products of Aβwere interspersedly distributedin extensive areas of cerebral cortex and hippocampus. Karyolysis, and derangement of microtubules was seen in zinc treated animals. Researchdevelopments led to the conclusion that local higher concentration of zinc in brain will result in intelligence and pathology characteristic to AD.

  10. Calculus for cognitive scientists higher order models and their analysis

    CERN Document Server

    Peterson, James K

    2016-01-01

    This book offers a self-study program on how mathematics, computer science and science can be profitably and seamlessly intertwined. This book focuses on two variable ODE models, both linear and nonlinear, and highlights theoretical and computational tools using MATLAB to explain their solutions. It also shows how to solve cable models using separation of variables and the Fourier Series.

  11. Hyperstate matrix models : extending demographic state spaces to higher dimensions

    NARCIS (Netherlands)

    Roth, G.; Caswell, H.

    2016-01-01

    1. Demographic models describe population dynamics in terms of the movement of individuals among states (e.g. size, age, developmental stage, parity, frailty, physiological condition). Matrix population models originally classified individuals by a single characteristic. This was enlarged to two cha

  12. Inelastic compression legging produces gradient compression and significantly higher skin surface pressures compared with an elastic compression stocking.

    Science.gov (United States)

    Kline, Cassie N; Macias, Brandon R; Kraus, Emily; Neuschwander, Timothy B; Angle, Niren; Bergan, John; Hargens, Alan R

    2008-01-01

    The purposes of this study were to (1) investigate compression levels beneath an inelastic legging equipped with a new pressure-adjustment system, (2) compare the inelastic compression levels with those provided by a well-known elastic stocking, and (3) evaluate each support's gradient compression production. Eighteen subjects without venous reflux and 12 patients with previously documented venous reflux received elastic and inelastic compression supports sized for the individual. Skin surface pressures under the elastic (Sigvaris 500, 30-40 mm Hg range, Sigvaris, Inc., Peachtree City, GA) and inelastic (CircAid C3 with Built-in-Pressure System [BPS], CircAid Medical Products, San Diego, CA) supports were measured using a calibrated Tekscan I-Scan device (Tekscan, Inc., Boston, MA). The elastic stocking produced significantly lower skin surface pressures than the inelastic legging. Mean pressures (+/- standard error) beneath the elastic stocking were 26 +/- 2 and 23 +/- 1 mm Hg at the ankle and below-knee regions, respectively. Mean pressures (+/- standard error) beneath the inelastic legging with the BPS were 50 +/- 3 and 38 +/- 2 mm Hg at the ankle and below-knee regions, respectively. Importantly, our study indicates that only the inelastic legging with the BPS produces significant ankle to knee gradient compression (p = .001).

  13. In Vitro-Produced Pancreas Organogenesis Models In Three Dimensions

    DEFF Research Database (Denmark)

    Greggio, Chiara; De Franceschi, Filippo; Grapin-Botton, Anne

    2015-01-01

    of miniature organs in a dish and are emerging for the pancreas, starting from embryonic progenitors and adult cells. This review focusses on the currently available systems and how these allow new types of questions to be addressed. We discuss the expected advancements including their potential to study human...... pancreas development and function as well as to develop diabetes models and therapeutic cells. Stem Cells 2014....

  14. Modeling nitrogen plasmas produced by intense electron beams

    Energy Technology Data Exchange (ETDEWEB)

    Angus, J. R.; Swanekamp, S. B.; Schumer, J. W.; Hinshelwood, D. D. [Plasma Physics Division, Naval Research Laboratory, Washington, DC 20375 (United States); Mosher, D.; Ottinger, P. F. [Independent contractors for NRL through Engility, Inc., Alexandria, Virginia 22314 (United States)

    2016-05-15

    A new gas–chemistry model is presented to treat the breakdown of a nitrogen gas with pressures on the order of 1 Torr from intense electron beams with current densities on the order of 10 kA/cm{sup 2} and pulse durations on the order of 100 ns. For these parameter regimes, the gas transitions from a weakly ionized molecular state to a strongly ionized atomic state on the time scale of the beam pulse. The model is coupled to a 0D–circuit model using the rigid–beam approximation that can be driven by specifying the time and spatial profiles of the beam pulse. Simulation results are in good agreement with experimental measurements of the line–integrated electron density from experiments done using the Gamble II generator at the Naval Research Laboratory. It is found that the species are mostly in the ground and metastable states during the atomic phase, but that ionization proceeds predominantly through thermal ionization of optically allowed states with excitation energies close to the ionization limit.

  15. On the hysteresis behaviors of the higher spin Ising model

    Science.gov (United States)

    Akıncı, Ümit

    2017-10-01

    Hysteresis characteristics of the general Spin-S (S > 1) Blume-Capel model have been studied within the effective field approximation. Particular emphasis has been paid on the large negative valued crystal field region and it has been demonstrated for this region that, Spin-S Blume-Capel model has 2 S windowed hysteresis loop in low temperatures. Some interesting results have been obtained such as nested characteristics of the hysteresis loops of successive spin-S Blume-Capel model. Effect of the rising crystal field and temperature on these hysteresis behaviors have been investigated in detail and physical mechanisms have been given.

  16. SyntEyes KTC: higher order statistical eye model for developing keratoconus.

    Science.gov (United States)

    Rozema, Jos J; Rodriguez, Pablo; Ruiz Hidalgo, Irene; Navarro, Rafael; Tassignon, Marie-José; Koppen, Carina

    2017-05-01

    To present and validate a stochastic eye model for developing keratoconus to e.g. improve optical corrective strategies. This could be particularly useful for researchers that do not have access to original keratoconic data. The Scheimpflug tomography, ocular biometry and wavefront of 145 keratoconic right eyes were collected. These data were processed using principal component analysis for parameter reduction, followed by a multivariate Gaussian fit that produces a stochastic model for keratoconus (SyntEyes KTC). The output of this model is filtered to remove the occasional incorrect topography patterns by either an automatic or manual procedure. Finally, the output of this keratoconus model is matched to that of the original model for normal eyes using the non-corneal biometry to obtain a description of keratoconus development. The synthetic data generated by the model were found to be significantly equal to the original data (non-parametric Mann-Whitney equivalence test; 145/154 passed). The variability of the synthetic data, however, was often significantly less than that of the original data, especially for the higher order Zernike terms of corneal elevation (non-parametric Levene test; p keratoconus progression. The synthetic data provided by the proposed keratoconus model closely resembles actual clinical data and may be used for a range of research applications when (sufficient) real data is not available. © 2017 The Authors Ophthalmic & Physiological Optics © 2017 The College of Optometrists.

  17. Higher genus correlators from the hermitian one-matrix model

    Energy Technology Data Exchange (ETDEWEB)

    Ambjoern, J. (Niels Bohr Inst., Copenhagen (Denmark)); Chekhov, L. (Steklov Mathematical Inst., Moscow (Russia)); Makeenko, Yu. (Inst. of Theoretical and Experimental Physics, Moscow (Russia))

    1992-05-28

    We develop an iterative algorithm for the genus expansion of the hermitian NxN one-matrix model (is the Penner model in an external field). By introducing moments of the external field, we prove that the genus g contribution to the m-loop correlator depends only on 3g-2+m lower moments (3g-2 for the partition function). We present the explicit results for the partition function and the one-loop correlator in genus one. We compare the correlators for the hermitian one-matrix model with those at zero momenta for c=1 CFT and show an agreement of the one-loop correlators for genus zero. (orig.).

  18. Higher-order models versus direct hierarchical models: g as superordinate or breadth factor?

    Directory of Open Access Journals (Sweden)

    GILLES E. GIGNAC

    2008-03-01

    Full Text Available Intelligence research appears to have overwhelmingly endorsed a superordinate (higher-order model conceptualization of g, in comparison to the relatively less well-known breadth conceptualization of g, as represented by the direct hierarchical model. In this paper, several similarities and distinctions between the indirect and direct hierarchical models are delineated. Based on the re-analysis of five correlation matrices, it was demonstrated via CFA that the conventional conception of g as a higher-order superordinate factor was likely not as plausible as a first-order breadth factor. The results are discussed in light of theoretical advantages of conceptualizing g as a first-order factor. Further, because the associations between group-factors and g are constrained to zero within a direct hierarchical model, previous observations of isomorphic associations between a lower-order group factor and g are questioned.

  19. The Complexity of Model Checking Higher-Order Fixpoint Logic

    DEFF Research Database (Denmark)

    Axelsson, Roland; Lange, Martin; Somla, Rafal

    2007-01-01

    of solving rather large parity games of small index. As a consequence of this we obtain an ExpTime upper bound on the expression complexity of each HFLk,m. The lower bound is established by a reduction from the word problem for alternating (k-1)-fold exponential space bounded Turing Machines. As a corollary...... provides complexity results for its model checking problem. In particular we consider its fragments HFLk,m which are formed using types of bounded order k and arity m only. We establish k-ExpTime-completeness for model checking each HFLk,m fragment. For the upper bound we reduce the problem to the problem...

  20. Multilevel Higher-Order Item Response Theory Models

    Science.gov (United States)

    Huang, Hung-Yu; Wang, Wen-Chung

    2014-01-01

    In the social sciences, latent traits often have a hierarchical structure, and data can be sampled from multiple levels. Both hierarchical latent traits and multilevel data can occur simultaneously. In this study, we developed a general class of item response theory models to accommodate both hierarchical latent traits and multilevel data. The…

  1. New Models of Hybrid Leadership in Global Higher Education

    Science.gov (United States)

    Tonini, Donna C.; Burbules, Nicholas C.; Gunsalus, C. K.

    2016-01-01

    This manuscript highlights the development of a leadership preparation program known as the Nanyang Technological University Leadership Academy (NTULA), exploring the leadership challenges unique to a university undergoing rapid growth in a highly multicultural context, and the hybrid model of leadership it developed in response to globalization.…

  2. Campus Sustainability: Emerging Curricula Models in Higher Education

    Science.gov (United States)

    Savelyeva, Tamara; McKenna, James R.

    2011-01-01

    Purpose: The purpose of this paper is to build a detailed description of the Global Seminar (GS) curricula model by exploring its on-the-ground participatory practices in America, Europe, Africa, Asia, and Australia. Design/methodology/approach: Within a qualitative research design framework, the authors interviewed 20 faculty members from the…

  3. Mixed Higher Order Variational Model for Image Recovery

    Directory of Open Access Journals (Sweden)

    Pengfei Liu

    2014-01-01

    Full Text Available A novel mixed higher order regularizer involving the first and second degree image derivatives is proposed in this paper. Using spectral decomposition, we reformulate the new regularizer as a weighted L1-L2 mixed norm of image derivatives. Due to the equivalent formulation of the proposed regularizer, an efficient fast projected gradient algorithm combined with monotone fast iterative shrinkage thresholding, called, FPG-MFISTA, is designed to solve the resulting variational image recovery problems under majorization-minimization framework. Finally, we demonstrate the effectiveness of the proposed regularization scheme by the experimental comparisons with total variation (TV scheme, nonlocal TV scheme, and current second degree methods. Specifically, the proposed approach achieves better results than related state-of-the-art methods in terms of peak signal to ratio (PSNR and restoration quality.

  4. Modeling higher education attractiveness to stand global environment

    Directory of Open Access Journals (Sweden)

    Leonel Cezar Rodrigues

    2016-01-01

    Full Text Available Inabilities to deal with the changing environment may lead Higher Education Institutions (HEI to loose institutional attractiveness. Digital transformation requires global insertion as essential feature to institutional attractiveness. Processes for international education seem to lack the links between real environmental trends and the internal capabilities to global education. HEI managers may approach endeavors to internationalize education combining ambidextrous strategy supported by consolidated resilience capabilities. The latest ones refer to building internal value attributes to increase institutional attractiveness assuring solid standing in the global environment. In this article, a theoretical essay, we approach the problem of creating resilience as a way of backing up ambidexterity to generate institutional attractiveness. The set of value attributes, on the other hand, may originate strategic routes to strengthen internal competences and to make the institution more attractive, as a dynamic capability.

  5. Precision Spectroscopy and Higher Spin symmetry in the ABJM model

    CERN Document Server

    Bianchi, Massimo; Samsonyan, Marine

    2010-01-01

    We revisit Kaluza-Klein compactification of 11-d supergravity on S^7/Z_k using group theory techniques that may find application in other flux vacua with internal coset spaces. Among the SO(2) neutral states, we identify marginal deformations and fields that couple to the recently discussed world-sheet instanton of Type IIA on CP^3. We also discuss charged states, dual to monopole operators, and the Z_k projection of the Osp(4|8) singleton and its tensor products. In particular, we show that the doubleton spectrum may account for N=6 higher spin symmetry enhancement in the limit of vanishing 't Hooft coupling in the boundary Chern-Simons theory.

  6. Goldilocks Models of Higher-Dimensional Inflation (including modulus stabilization)

    CERN Document Server

    Burgess, C P; Hayman, Peter; Patil, Subodh P

    2016-01-01

    We explore the mechanics of inflation in simplified extra-dimensional models involving an inflaton interacting with the Einstein-Maxwell system in two extra dimensions. The models are Goldilocks-like in that they are just complicated enough to include a mechanism to stabilize the extra-dimensional size, yet simple enough to solve the full 6D field equations using basic tools. The solutions are not limited to the effective 4D regime with H m_KK, but when they do standard 4D fluctuation calculations need not apply. When in a 4D regime the solutions predict eta ~ 0 hence n_s ~ 0.96 and r ~ 0.096 and so are ruled out if tensor modes remain unseen. Analysis of general parameters is difficult without a full 6D fluctuation calculation.

  7. How robust are probabilistic models of higher-level cognition?

    Science.gov (United States)

    Marcus, Gary F; Davis, Ernest

    2013-12-01

    An increasingly popular theory holds that the mind should be viewed as a near-optimal or rational engine of probabilistic inference, in domains as diverse as word learning, pragmatics, naive physics, and predictions of the future. We argue that this view, often identified with Bayesian models of inference, is markedly less promising than widely believed, and is undermined by post hoc practices that merit wholesale reevaluation. We also show that the common equation between probabilistic and rational or optimal is not justified.

  8. Green Education Concepts & Strategies in Higher Education Model

    OpenAIRE

    Sreeramana Aithal; Prithi Rao

    2016-01-01

    Green Education in the service sector is expected to transform education sector and is combined with the trend of world economy development. Environmental benefits and sustainability are two characteristics of Green education. In the green education model, service is expanded as, what kinds of education is provided by organizations (the process of service creation), how such services are transferred to the customers, how will the benefits be captured by providers around service...

  9. Goldilocks models of higher-dimensional inflation (including modulus stabilization)

    Science.gov (United States)

    Burgess, C. P.; Enns, Jared J. H.; Hayman, Peter; Patil, Subodh P.

    2016-08-01

    We explore the mechanics of inflation within simplified extra-dimensional models involving an inflaton interacting with the Einstein-Maxwell system in two extra dimensions. The models are Goldilocks-like inasmuch as they are just complicated enough to include a mechanism to stabilize the extra-dimensional size (or modulus), yet simple enough to solve explicitly the full extra-dimensional field equations using only simple tools. The solutions are not restricted to the effective 4D regime with H ll mKK (the latter referring to the characteristic mass splitting of the Kaluza-Klein excitations) because the full extra-dimensional Einstein equations are solved. This allows an exploration of inflationary physics in a controlled calculational regime away from the usual four-dimensional lamp-post. The inclusion of modulus stabilization is important because experience with string models teaches that this is usually what makes models fail: stabilization energies easily dominate the shallow potentials required by slow roll and so open up directions to evolve that are steeper than those of the putative inflationary direction. We explore (numerically and analytically) three representative kinds of inflationary scenarios within this simple setup. In one the radion is trapped in an inflaton-dependent local minimum whose non-zero energy drives inflation. Inflation ends as this energy relaxes to zero when the inflaton finds its own minimum. The other two involve power-law scaling solutions during inflation. One of these is a dynamical attractor whose features are relatively insensitive to initial conditions but whose slow-roll parameters cannot be arbitrarily small; the other is not an attractor but can roll much more slowly, until eventually transitioning to the attractor. The scaling solutions can satisfy H > mKK, but when they do standard 4D fluctuation calculations need not apply. When in a 4D regime the solutions predict η simeq 0 and so r simeq 0.11 when ns simeq 0.96 and so

  10. Modeling the Aerodynamic Lift Produced by Oscillating Airfoils at Low Reynolds Number

    CERN Document Server

    Khalid, Muhammad Saif Ullah

    2015-01-01

    For present study, setting Strouhal Number (St) as control parameter, numerical simulations for flow past oscillating NACA-0012 airfoil at 1,000 Reynolds Numbers (Re) are performed. Temporal profiles of unsteady forces; lift and thrust, and their spectral analysis clearly indicate the solution to be a period-1 attractor for low Strouhal numbers. This study reveals that aerodynamic forces produced by plunging airfoil are independent of initial kinematic conditions of airfoil that proves the existence of limit cycle. Frequencies present in the oscillating lift force are composed of fundamental (fs), even and odd harmonics (3fs) at higher Strouhal numbers. Using numerical simulations, shedding frequencies (f_s) were observed to be nearly equal to the excitation frequencies in all the cases. Unsteady lift force generated due to the plunging airfoil is modeled by modified van der Pol oscillator. Using method of multiple scales and spectral analysis of steady-state CFD solutions, frequencies and damping terms in th...

  11. Preserving the Public Good: Presenting an Organizational Model for the Changing Future of Higher Education

    Science.gov (United States)

    Garcia, Stephanie Parra

    2011-01-01

    Institutions of higher education face financial pressure to become self-sustaining (Gumport, 2001; 2000). This rapidly growing economic demand is negatively affecting the social mission of higher education (Kezar, 2004). Scholars suggest the implementation of a new model of higher education, one that blends a for-profit model with the traditional…

  12. Selection of Sinopec Lubricating Oil Producing Bases by Using the AHP Model

    Institute of Scientific and Technical Information of China (English)

    Song Yunchang; Song Zhaozheng; Zheng Chengguo; Jiang Qingzhe; Xu Chunming

    2007-01-01

    The factors affecting the development of Sinopec lubricating oil were analyzed in this paper,and an analytic hierarchy process (AHP) model for selecting lubricating-oil producing bases was developed. By using this model,nine lubricating oil producing companies under Sinopec were comprehensively evaluated. The evaluation result showed that the Maoming Lubricating Oil Company (Guangdong province),Jingmen Lubricating Oil Company (Hubei province) and Changcheng Lube Oil Company (Beijing) are top three choices,and should be developed preferentially for the development of Sinopec producing bases of lubricating oil in the future. The conclusions provide the theoretical basis for selecting lubricating oil producing bases for decision makers.

  13. Emerging Governance in State-Level Higher Education: Competing Pressures and Models

    Science.gov (United States)

    Mortensen, Brad Leon

    2009-01-01

    This dissertation study considered reforms in state-level higher education governance in the United States. Many researchers have suggested the emergence of market-oriented models in higher education governance. This study explored the existence of market-oriented models as well as other reform models in two western states, Utah and Washington. …

  14. Ability, Breadth, and Parsimony in Computational Models of Higher-Order Cognition

    Science.gov (United States)

    Cassimatis, Nicholas L.; Bello, Paul; Langley, Pat

    2008-01-01

    Computational models will play an important role in our understanding of human higher-order cognition. How can a model's contribution to this goal be evaluated? This article argues that three important aspects of a model of higher-order cognition to evaluate are (a) its ability to reason, solve problems, converse, and learn as well as people do;…

  15. Conformal invariant Painlevé expansions and higher dimensional integrable models

    Institute of Scientific and Technical Information of China (English)

    楼森岳

    1999-01-01

    After the (1+1)-dimensional nonlinear Schr(?)dinger equation is embedded in higher dimensions and the usual singularity analysis approach is extended such that all the Painlev(?) expansion coefficients are conformal invariant, many higher dimensional integrable models are got after the nontrivial conformal invariant expansion coefficients are taken to be zero simply. The Painlev(?) properties of the obtained higher dimensional models (including some (3+1)-dimensional models) are proved.

  16. A seasonal model of contracts between a monopsonistic processor and smallholder pepper producers in Costa Rica

    NARCIS (Netherlands)

    Sáenz Segura, F.; Haese, D' M.F.C.; Schipper, R.A.

    2010-01-01

    We model the contractual arrangements between smallholder pepper (Piper nigrum L.) producers and a single processor in Costa Rica. Producers in the El Roble settlement sell their pepper to only one processing firm, which exerts its monopsonistic bargaining power by setting the purchase price of

  17. A seasonal model of contracts between a monopsonistic processor and smallholder pepper producers in Costa Rica

    NARCIS (Netherlands)

    Sáenz Segura, F.; Haese, D' M.F.C.; Schipper, R.A.

    2010-01-01

    We model the contractual arrangements between smallholder pepper (Piper nigrum L.) producers and a single processor in Costa Rica. Producers in the El Roble settlement sell their pepper to only one processing firm, which exerts its monopsonistic bargaining power by setting the purchase price of fres

  18. Effects of build parameters on linear wear loss in plastic part produced by fused deposition modeling

    Science.gov (United States)

    Mohamed, Omar Ahmed; Masood, Syed Hasan; Bhowmik, Jahar Lal

    2017-07-01

    Fused Deposition Modeling (FDM) is one of the prominent additive manufacturing technologies for producing polymer products. FDM is a complex additive manufacturing process that can be influenced by many process conditions. The industrial demands required from the FDM process are increasing with higher level product functionality and properties. The functionality and performance of FDM manufactured parts are greatly influenced by the combination of many various FDM process parameters. Designers and researchers always pay attention to study the effects of FDM process parameters on different product functionalities and properties such as mechanical strength, surface quality, dimensional accuracy, build time and material consumption. However, very limited studies have been carried out to investigate and optimize the effect of FDM build parameters on wear performance. This study focuses on the effect of different build parameters on micro-structural and wear performance of FDM specimens using definitive screening design based quadratic model. This would reduce the cost and effort of additive manufacturing engineer to have a systematic approachto make decision among the manufacturing parameters to achieve the desired product quality.

  19. Higher-Order Process Modeling: Product-Lining, Variability Modeling and Beyond

    Directory of Open Access Journals (Sweden)

    Johannes Neubauer

    2013-09-01

    Full Text Available We present a graphical and dynamic framework for binding and execution of business process models. It is tailored to integrate 1 ad hoc processes modeled graphically, 2 third party services discovered in the (Internet, and 3 (dynamically synthesized process chains that solve situation-specific tasks, with the synthesis taking place not only at design time, but also at runtime. Key to our approach is the introduction of type-safe stacked second-order execution contexts that allow for higher-order process modeling. Tamed by our underlying strict service-oriented notion of abstraction, this approach is tailored also to be used by application experts with little technical knowledge: users can select, modify, construct and then pass (component processes during process execution as if they were data. We illustrate the impact and essence of our framework along a concrete, realistic (business process modeling scenario: the development of Springer's browser-based Online Conference Service (OCS. The most advanced feature of our new framework allows one to combine online synthesis with the integration of the synthesized process into the running application. This ability leads to a particularly flexible way of implementing self-adaption, and to a particularly concise and powerful way of achieving variability not only at design time, but also at runtime.

  20. Understanding the Concept of the Entrepreneurial University from the Perspective of Higher Education Models

    Science.gov (United States)

    Sam, Chanphirun; van der Sijde, Peter

    2014-01-01

    Over the last few decades, globalization and ever-increasing demands of the knowledge-based economy have caused higher education in most countries around the world to undergo significant transformation. Notwithstanding the dramatic changes in higher education, it is clearly noticed that the influence of the European higher education models is…

  1. Developing a generic model for total quality management in higher education in Saudi Arabia.

    Science.gov (United States)

    Al-Shafei, Ahmad I; Bin Abdulrahman, Khalid; Al-Qumaizi, Khalid I; El-Mardi, Abdelmoniem S

    2015-04-01

    The field of higher education has been progressing at a rapid pace in the Kingdom of Saudi Arabia over the past decade, with doubling the number of government and private universities and colleges. Quality and accreditation are of great importance to higher education institutes world-wide. Thus, developing a generic model for quality management in higher education is badly needed in the country.

  2. Modeling Reflective Higher-Order Constructs using Three Approaches with PLS Path Modeling: A Monte Carlo Comparison

    NARCIS (Netherlands)

    Wilson, B.; Henseler, J.

    2007-01-01

    Many studies in the social sciences are increasingly modeling higher-order constructs. PLS can be used to investigate models at a higher level of abstraction (Lohmöller, 1989). It is often chosen due to its’ ability to estimate complex models (Chin, 1998). The primary goal of this paper is to demons

  3. A Case Study of Higher Education Competency Models Utilizing an Assessment Framework

    Science.gov (United States)

    Uden, Jayme

    2012-01-01

    The overall purpose of this study is to explore the creation and implementation of competency models in higher education masters level preparation programs. The study answers five research questions. Why and how did two higher education preparation programs create a professional competency model for the graduate students in the program and what…

  4. A Race to the Bottom: MOOCs and Higher Education Business Models

    Science.gov (United States)

    Kalman, Yoram M.

    2014-01-01

    This is a critical examination of the claims that innovations such as massive open online courses (MOOCs) will disrupt the business models of the higher education sector. It describes what business models are, analyses the business model of free MOOCs offered by traditional universities and compares that model to that of paid online courses…

  5. A Race to the Bottom: MOOCs and Higher Education Business Models

    Science.gov (United States)

    Kalman, Yoram M.

    2014-01-01

    This is a critical examination of the claims that innovations such as massive open online courses (MOOCs) will disrupt the business models of the higher education sector. It describes what business models are, analyses the business model of free MOOCs offered by traditional universities and compares that model to that of paid online courses…

  6. A Systematic Review of Agent-Based Modelling and Simulation Applications in the Higher Education Domain

    Science.gov (United States)

    Gu, X.; Blackmore, K. L.

    2015-01-01

    This paper presents the results of a systematic review of agent-based modelling and simulation (ABMS) applications in the higher education (HE) domain. Agent-based modelling is a "bottom-up" modelling paradigm in which system-level behaviour (macro) is modelled through the behaviour of individual local-level agent interactions (micro).…

  7. Bone invading NSCLC cells produce IL-7: mice model and human histologic data

    Directory of Open Access Journals (Sweden)

    Quarto Rodolfo

    2010-01-01

    Full Text Available Abstract Background Bone metastases are a common and dismal consequence of lung cancer that is a leading cause of death. The role of IL-7 in promoting bone metastases has been previously investigated in NSCLC, but many aspects remain to be disclosed. To further study IL-7 function in bone metastasis, we developed a human-in-mice model of bone aggression by NSCLC and analyzed human bone metastasis biopsies. Methods We used NOD/SCID mice implanted with human bone. After bone engraftment, two groups of mice were injected subcutaneously with A549, a human NSCLC cell line, either close or at the contralateral flank to the human bone implant, while a third control group did not receive cancer cells. Tumor and bone vitality and IL-7 expression were assessed in implanted bone, affected or not by A549. Serum IL-7 levels were evaluated by ELISA. IL-7 immunohistochemistry was performed on 10 human bone NSCLC metastasis biopsies for comparison. Results At 12 weeks after bone implant, we observed osteogenic activity and neovascularization, confirming bone vitality. Tumor aggressive cells implanted close to human bone invaded the bone tissue. The bone-aggressive cancer cells were positive for IL-7 staining both in the mice model and in human biopsies. Higher IL-7 serum levels were found in mice injected with A549 cells close to the bone implant compared to mice injected with A549 cells in the flank opposite to the bone implant. Conclusions We demonstrated that bone-invading cells express and produce IL-7, which is known to promote osteoclast activation and osteolytic lesions. Tumor-bone interaction increases IL-7 production, with an increase in IL-7 serum levels. The presented mice model of bone invasion by contiguous tumor is suitable to study bone-tumor cell interaction. IL-7 plays a role in the first steps of metastatic process.

  8. More ornamented females produce higher-quality offspring in a socially monogamous bird: an experimental study in the great tit (Parus major).

    Science.gov (United States)

    Remeš, Vladimír; Matysioková, Beata

    2013-03-25

    Animals are often conspicuously colored and explanations range from aposematism and mimicry to sexual selection. Although sexual selection explains vivid coloration in males, functional significance of vivid coloration in females of socially monogamous species remains unclear. The hypothesis of mutual mate choice predicts that more ornamented females produce offspring of higher quality. We tested this prediction in the great tit (Parus major), a small, insectivorous, socially monogamous passerine. In both females and males we quantified three ornaments that have been hypothesized to have signaling role in this species (size of black breast stripe, carotenoid chroma of yellow breast feathers, immaculateness of the white cheek). We swapped broods between nests soon after hatching, thus separating genetic plus pre-hatching vs. post-hatching effects on offspring performance. Body mass of offspring at 14 days of age was positively related to the area of black breast stripe of genetic mothers. Immune response to a novel antigen (phytohaemagglutinin) at 14 days of age was positively related to the immaculateness of the white cheek patch of both genetic and foster mothers. We showed that females with more elaborate ornaments produced higher-quality offspring and we discuss potential proximate mechanisms of these relationships. We conclude that as more elaborate ornaments were reliable signals of offspring quality, direct selection by male mate choice might have been responsible for the evolution and/or maintenance of these signaling traits in females.

  9. Higher thermostability of l-lactate dehydrogenases is a key factor in decreasing the optical purity of d-lactic acid produced from Lactobacillus coryniformis.

    Science.gov (United States)

    Gu, Sol-A; Jun, Chanha; Joo, Jeong Chan; Kim, Seil; Lee, Seung Hwan; Kim, Yong Hwan

    2014-05-10

    Lactobacillus coryniformis is known to produce d-lactic acid as a dominant fermentation product at a cultivation temperature of approximately 30°C. However, the considerable production of l-lactic acid is observed when the fermentation temperature is greater than 40°C. Because optically pure lactates are synthesized from pyruvate by the catalysis of chiral-specific d- or l-lactate dehydrogenase, the higher thermostability of l-LDHs is assumed to be one of the key factors decreasing the optical purity of d-lactic acid produced from L. coryniformis at high temperature. To verify this hypothesis, two types of d-ldh genes and six types of l-ldh genes based on the genomic information of L. coryniformis were synthesized and expressed in Escherichia coli. Among the LDHs tested, five LDHs showed activity and were used to construct polyclonal antibodies. d-LDH1, l-LDH2, and l-LDH3 were found to be expressed in L. coryniformis by Western blotting analysis. The half-life values (t1/2) of the LDHs at 40°C were estimated to be 10.50, 41.76, and 2311min, and the T50(10) values were 39.50, 39.90, and 58.60°C, respectively. In addition, the Tm values were 36.0, 41.0, and 62.4°C, respectively, which indicates that l-LDH has greater thermostability than d-LDH. The higher thermostability of l-LDHs compared with that of d-LDH1 may be a major reason why the enantiopurity of d-lactic acid is decreased at high fermentation temperatures. The key enzymes characterized will suggest a direction for the design of genetically modified lactic acid bacteria to produce optically pure d-lactic acid. Copyright © 2014 Elsevier Inc. All rights reserved.

  10. A generic model for keeping quality of vegetable produce during storage and distribution

    NARCIS (Netherlands)

    Tijskens, L.M.M.; Polderdijk, J.J.

    1996-01-01

    A generic model on the keeping quality of perishable produce was formulated, based on the kinetics of the decrease of individual quality attributes. The model includes the effects of temperature, chilling injury and different levels of initial quality and of quality acceptance limits. Keeping qualit

  11. Modeling of laser produced plasma and z-pinch x-ray lasers

    Energy Technology Data Exchange (ETDEWEB)

    Dunn, J; Frati, M; Gonzales, J J; Kalashnikov, M P; Marconi, M C; Moreno, C H; Nickels, P V; Osterheld, A L; Rocca, J J; Sandner, W; Shlyaptsev, V N

    1999-02-07

    In this work we describe our theoretical activities in two directions of interest. First, we discuss progress in modeling laser produced plasmas mostly related to transient collisional excitation scheme experiments with Ne- and recently with Ni-like ions. Calculations related to the delay between laser pulses, transient gain duration and hybrid laser/capillary approach are described in more detail. Second, the capillary discharge plasma research, extended to wider range of currents and rise-times has been outlined. We have systematically evaluated the major plasma and atomic kinetic properties by comparing near- and far-field X-ray laser output with that for the capillary Argon X-ray laser operating under typical current values. Consistent with the experiment insight was obtained for the 469{angstrom} X-ray laser shadowgraphy experiments with very small kiloamp currents. At higher currents, as much as {approximately}200 kA we evaluated plasma temperature, density and compared x-ray source size and emitted spectra.

  12. A COMPARISON OF THE TENSILE STRENGTH OF PLASTIC PARTS PRODUCED BY A FUSED DEPOSITION MODELING DEVICE

    Directory of Open Access Journals (Sweden)

    Juraj Beniak

    2015-12-01

    Full Text Available Rapid Prototyping systems are nowadays increasingly used in many areas of industry, not only for producing design models but also for producing parts for final use. We need to know the properties of these parts. When we talk about the Fused Deposition Modeling (FDM technique and FDM devices, there are many possible settings for devices and models which could influence the properties of a final part. In addition, devices based on the same principle may use different operational software for calculating the tool path, and this may have a major impact. The aim of this paper is to show the tensile strength value for parts produced from different materials on the Fused Deposition Modeling device when the horizontal orientation of the specimens is changed.

  13. Mathematical modeling of polystyrene particle size distribution produced by suspension polymerization

    Directory of Open Access Journals (Sweden)

    Machado R.A.F.

    2000-01-01

    Full Text Available Particle size distribution (PSD of polystyrene particles produced by suspension polymerization is of fundamental importance in determining suspension stability and product quality attributes. Within a population balance framework, a model is proposed for suspension polymerization reactors to describe the evolution of the PSD. The model includes description of breakage and coalescence rates in terms of reaction kinetics and rheology of the dispersed phase. The model is validated with experimental data of styrene suspension polymerization.

  14. Developing a Sustainable Financial Model in Higher Education for Open Educational Resources

    Science.gov (United States)

    Annand, David

    2015-01-01

    Financial issues regarding the sustainable production, dissemination, and use of Open Educational Resources (OER) in higher education are reviewed and proposed solutions critiqued. Use of OER produce demonstrable cost savings for students. Yet OER development continues to rely almost completely on government and philanthropic funding. This…

  15. Higher-order triangular spectral element method with optimized cubature points for seismic wavefield modeling

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Youshan, E-mail: ysliu@mail.iggcas.ac.cn [State Key Laboratory of Lithospheric Evolution, Institute of Geology and Geophysics, Chinese Academy of Sciences, Beijing, 100029 (China); Teng, Jiwen, E-mail: jwteng@mail.iggcas.ac.cn [State Key Laboratory of Lithospheric Evolution, Institute of Geology and Geophysics, Chinese Academy of Sciences, Beijing, 100029 (China); Xu, Tao, E-mail: xutao@mail.iggcas.ac.cn [State Key Laboratory of Lithospheric Evolution, Institute of Geology and Geophysics, Chinese Academy of Sciences, Beijing, 100029 (China); CAS Center for Excellence in Tibetan Plateau Earth Sciences, Beijing, 100101 (China); Badal, José, E-mail: badal@unizar.es [Physics of the Earth, Sciences B, University of Zaragoza, Pedro Cerbuna 12, 50009 Zaragoza (Spain)

    2017-05-01

    The mass-lumped method avoids the cost of inverting the mass matrix and simultaneously maintains spatial accuracy by adopting additional interior integration points, known as cubature points. To date, such points are only known analytically in tensor domains, such as quadrilateral or hexahedral elements. Thus, the diagonal-mass-matrix spectral element method (SEM) in non-tensor domains always relies on numerically computed interpolation points or quadrature points. However, only the cubature points for degrees 1 to 6 are known, which is the reason that we have developed a p-norm-based optimization algorithm to obtain higher-order cubature points. In this way, we obtain and tabulate new cubature points with all positive integration weights for degrees 7 to 9. The dispersion analysis illustrates that the dispersion relation determined from the new optimized cubature points is comparable to that of the mass and stiffness matrices obtained by exact integration. Simultaneously, the Lebesgue constant for the new optimized cubature points indicates its surprisingly good interpolation properties. As a result, such points provide both good interpolation properties and integration accuracy. The Courant–Friedrichs–Lewy (CFL) numbers are tabulated for the conventional Fekete-based triangular spectral element (TSEM), the TSEM with exact integration, and the optimized cubature-based TSEM (OTSEM). A complementary study demonstrates the spectral convergence of the OTSEM. A numerical example conducted on a half-space model demonstrates that the OTSEM improves the accuracy by approximately one order of magnitude compared to the conventional Fekete-based TSEM. In particular, the accuracy of the 7th-order OTSEM is even higher than that of the 14th-order Fekete-based TSEM. Furthermore, the OTSEM produces a result that can compete in accuracy with the quadrilateral SEM (QSEM). The high accuracy of the OTSEM is also tested with a non-flat topography model. In terms of computational

  16. John Carroll’s Views on Intelligence: Bi-Factor vs. Higher-Order Models

    Directory of Open Access Journals (Sweden)

    A. Alexander Beaujean

    2015-10-01

    Full Text Available The development of factor models is inextricably tied to the history of intelligence research. One of the most commonly-cited scholars in the field is John Carroll, whose three-stratum theory of cognitive ability has been one of the most influential models of cognitive ability in the past 20 years. Nonetheless, there is disagreement about how Carroll conceptualized the factors in his model. Some argue that his model is best represented through a higher-order model, while others argue that a bi-factor model is a better representation. Carroll was explicit about what he perceived the best way to represent his model, but his writings are not always easy to understand. In this article, I clarify his position by first describing the details and implications of bi-factor and higher-order models then show that Carroll’s published views are better represented by a bi-factor model.

  17. Magnetic resonance Spectroscopy with Linear Algebraic Modeling (SLAM) for higher speed and sensitivity

    Science.gov (United States)

    Zhang, Yi; Gabr, Refaat E.; Schär, Michael; Weiss, Robert G.; Bottomley, Paul A.

    2012-05-01

    Speed and signal-to-noise ratio (SNR) are critical for localized magnetic resonance spectroscopy (MRS) of low-concentration metabolites. Matching voxels to anatomical compartments a priori yields better SNR than the spectra created by summing signals from constituent chemical-shift-imaging (CSI) voxels post-acquisition. Here, a new method of localized Spectroscopy using Linear Algebraic Modeling (SLAM) is presented, that can realize this additional SNR gain. Unlike prior methods, SLAM generates spectra from C signal-generating anatomic compartments utilizing a CSI sequence wherein essentially only the C central k-space phase-encoding gradient steps with highest SNR are retained. After MRI-based compartment segmentation, the spectra are reconstructed by solving a sub-set of linear simultaneous equations from the standard CSI algorithm. SLAM is demonstrated with one-dimensional CSI surface coil phosphorus MRS in phantoms, the human leg and the heart on a 3T clinical scanner. Its SNR performance, accuracy, sensitivity to registration errors and inhomogeneity, are evaluated. Compared to one-dimensional CSI, SLAM yielded quantitatively the same results 4-times faster in 24 cardiac patients and healthy subjects. SLAM is further extended with fractional phase-encoding gradients that optimize SNR and/or minimize both inter- and intra-compartmental contamination. In proactive cardiac phosphorus MRS of six healthy subjects, both SLAM and fractional-SLAM (fSLAM) produced results indistinguishable from CSI while preserving SNR gains of 36-45% in the same scan-time. Both SLAM and fSLAM are simple to implement and reduce the minimum scan-time for CSI, which otherwise limits the translation of higher SNR achievable at higher field strengths to faster scanning.

  18. Magnetic resonance Spectroscopy with Linear Algebraic Modeling (SLAM) for higher speed and sensitivity.

    Science.gov (United States)

    Zhang, Yi; Gabr, Refaat E; Schär, Michael; Weiss, Robert G; Bottomley, Paul A

    2012-05-01

    Speed and signal-to-noise ratio (SNR) are critical for localized magnetic resonance spectroscopy (MRS) of low-concentration metabolites. Matching voxels to anatomical compartments a priori yields better SNR than the spectra created by summing signals from constituent chemical-shift-imaging (CSI) voxels post-acquisition. Here, a new method of localized Spectroscopy using Linear Algebraic Modeling (SLAM) is presented, that can realize this additional SNR gain. Unlike prior methods, SLAM generates spectra from C signal-generating anatomic compartments utilizing a CSI sequence wherein essentially only the C central k-space phase-encoding gradient steps with highest SNR are retained. After MRI-based compartment segmentation, the spectra are reconstructed by solving a sub-set of linear simultaneous equations from the standard CSI algorithm. SLAM is demonstrated with one-dimensional CSI surface coil phosphorus MRS in phantoms, the human leg and the heart on a 3T clinical scanner. Its SNR performance, accuracy, sensitivity to registration errors and inhomogeneity, are evaluated. Compared to one-dimensional CSI, SLAM yielded quantitatively the same results 4-times faster in 24 cardiac patients and healthy subjects. SLAM is further extended with fractional phase-encoding gradients that optimize SNR and/or minimize both inter- and intra-compartmental contamination. In proactive cardiac phosphorus MRS of six healthy subjects, both SLAM and fractional-SLAM (fSLAM) produced results indistinguishable from CSI while preserving SNR gains of 36-45% in the same scan-time. Both SLAM and fSLAM are simple to implement and reduce the minimum scan-time for CSI, which otherwise limits the translation of higher SNR achievable at higher field strengths to faster scanning.

  19. Biogeographical distribution analysis of hydrocarbon degrading and biosurfactant producing genes suggests that near-equatorial biomes have higher abundance of genes with potential for bioremediation.

    Science.gov (United States)

    Oliveira, Jorge S; Araújo, Wydemberg J; Figueiredo, Ricardo M; Silva-Portela, Rita C B; de Brito Guerra, Alaine; da Silva Araújo, Sinara Carla; Minnicelli, Carolina; Carlos, Aline Cardoso; de Vasconcelos, Ana Tereza Ribeiro; Freitas, Ana Teresa; Agnez-Lima, Lucymara F

    2017-07-27

    biogeographical distribution of hydrocarbon degrading and biosurfactant producing genes. Our principle results can be seen as an important step forward in the application of bioremediation techniques, by considering the biostimulation, optimization or manipulation of a starting microbial consortia from the areas with higher degradation and biosurfactant producing genetic diversity.

  20. On the use of shockwave models in laser produced plasma expansion

    Energy Technology Data Exchange (ETDEWEB)

    De Posada, E; Arronte, M A; Ponce, L; Rodriguez, E; Flores, T [Centro de Investigacion en Ciencia Aplicada y TecnologIa Avanzada, Unidad Altamira, Tamaulipas (Mexico); Lunney, J G, E-mail: edeposada@ipn.mx [School of Physics, Trinity College Dublin (Ireland)

    2011-01-01

    Interaction of medium to high peak power laser pulses with solid materials produces a plasma that expands supersonically. Expansions of such plasmas have been studied and several models have been proposed to describe it. This work presents a study of the expansion of laser produced plasmas in both vacuum and gas environment by using Langmuir probe and photography. It compares some of the most used models to identify that which better describes the expansion process. In vacuum, such process is properly described by the Anisimov model. However when expanding in a background gas it is found that the Sedov-Taylor model fits properly the position of generated shockwave but overestimates both kinetic energy and pressure of the expanding plasma. Such problem is solved by using a modification of the Freiwald-Axford model. Finally it is demonstrated that after the plasma stopping distance the plasma inters in a diffusive regime.

  1. How does higher frequency monitoring data affect the calibration of a process-based water quality model?

    Science.gov (United States)

    Jackson-Blake, Leah; Helliwell, Rachel

    2015-04-01

    Process-based catchment water quality models are increasingly used as tools to inform land management. However, for such models to be reliable they need to be well calibrated and shown to reproduce key catchment processes. Calibration can be challenging for process-based models, which tend to be complex and highly parameterised. Calibrating a large number of parameters generally requires a large amount of monitoring data, spanning all hydrochemical conditions. However, regulatory agencies and research organisations generally only sample at a fortnightly or monthly frequency, even in well-studied catchments, often missing peak flow events. The primary aim of this study was therefore to investigate how the quality and uncertainty of model simulations produced by a process-based, semi-distributed catchment model, INCA-P (the INtegrated CAtchment model of Phosphorus dynamics), were improved by calibration to higher frequency water chemistry data. Two model calibrations were carried out for a small rural Scottish catchment: one using 18 months of daily total dissolved phosphorus (TDP) concentration data, another using a fortnightly dataset derived from the daily data. To aid comparability, calibrations were carried out automatically using the Markov Chain Monte Carlo - DiffeRential Evolution Adaptive Metropolis (MCMC-DREAM) algorithm. Calibration to daily data resulted in improved simulation of peak TDP concentrations and improved model performance statistics. Parameter-related uncertainty in simulated TDP was large when fortnightly data was used for calibration, with a 95% credible interval of 26 μg/l. This uncertainty is comparable in size to the difference between Water Framework Directive (WFD) chemical status classes, and would therefore make it difficult to use this calibration to predict shifts in WFD status. The 95% credible interval reduced markedly with the higher frequency monitoring data, to 6 μg/l. The number of parameters that could be reliably auto

  2. Construction of special eye models for investigation of chromatic and higher-order aberrations of eyes.

    Science.gov (United States)

    Zhai, Yi; Wang, Yan; Wang, Zhaoqi; Liu, Yongji; Zhang, Lin; He, Yuanqing; Chang, Shengjiang

    2014-01-01

    An achromatic element eliminating only longitudinal chromatic aberration (LCA) while maintaining transverse chromatic aberration (TCA) is established for the eye model, which involves the angle formed by the visual and optical axis. To investigate the impacts of higher-order aberrations on vision, the actual data of higher-order aberrations of human eyes with three typical levels are introduced into the eye model along visual axis. Moreover, three kinds of individual eye models are established to investigate the impacts of higher-order aberrations, chromatic aberration (LCA+TCA), LCA and TCA on vision under the photopic condition, respectively. Results show that for most human eyes, the impact of chromatic aberration on vision is much stronger than that of higher-order aberrations, and the impact of LCA in chromatic aberration dominates. The impact of TCA is approximately equal to that of normal level higher-order aberrations and it can be ignored when LCA exists.

  3. Numerical Models of Higher-Order Boussinesq Equations and Comparisons with Laboratory Measurement

    Institute of Scientific and Technical Information of China (English)

    邹志利; 张晓莉

    2001-01-01

    Nonlinear water wave propagation passing a submerged shelf is studied experimentally and numerically. The applicability of two different wave propagation models has been investigated. One is higher-order Boussinesq equationsderived by Zou (1999) and the other is the classic Boussinesq equations. Physical experiments are conducted, three differ-ent front slopes (1:10, 1:5 and 1:2) of the shelf are set up in the experiment and their effects on wave propagation are in-vestigated. Comparisons of numerical results with test data are made, the model of higher-order Boussinesq equationsagrees much better with the measurements than the model of the classical Boussinesq equations. The results show thatthe higher-order Boussinesq equations can also be applied to the steeper slope case although the mild slope assumption isemployed in the derivation of the higher order terms of higher order Boussinesq equations.

  4. An Inventory Model with Price and Quality Dependent Demand Where Some Items Produced Are Defective

    Directory of Open Access Journals (Sweden)

    Tapan Kumar Datta

    2013-01-01

    Full Text Available This paper analyzes an inventory system for joint determination of product quality and selling price where a fraction of items produced are defective. It is assumed that only a fraction of defective items can be repaired/reworked. The demand rate depends upon both the quality and the selling price of the product. The production rate, unit price, and carrying cost depend upon the quality of the items produced. Quality index is used to determine the quality of the product. An algorithm is provided to solve the model with given values of model parameters. Sensitivity analysis has also been performed.

  5. A new fuzzy multi-objective higher order moment portfolio selection model for diversified portfolios

    Science.gov (United States)

    Yue, Wei; Wang, Yuping

    2017-01-01

    Due to the important effect of the higher order moments to portfolio returns, the aim of this paper is to make use of the third and fourth moments for fuzzy multi-objective portfolio selection model. Firstly, in order to overcome the low diversity of the obtained solution set and lead to corner solutions for the conventional higher moment portfolio selection models, a new entropy function based on Minkowski measure is proposed as a new objective function and a novel fuzzy multi-objective weighted possibilistic higher order moment portfolio model is presented. Secondly, to solve the proposed model efficiently, a new multi-objective evolutionary algorithm is designed. Thirdly, several portfolio performance evaluation techniques are used to evaluate the performance of the portfolio models. Finally, some experiments are conducted by using the data of Shanghai Stock Exchange and the results indicate the efficiency and effectiveness of the proposed model and algorithm.

  6. Reforming Iraqi Journalism and Mass Communication Higher Education: Adapting the UNESCO Model Curricula for Journalism Education to Iraqi Higher Education

    Science.gov (United States)

    Pavlik, John V.; Laufer, Peter D.; Burns, David P.; Ataya, Ramzi T.

    2012-01-01

    Journalism and mass communication higher education in Iraq is well established but largely isolated from global developments since the 1970s. In the post-Iraq war period, the United Nations Educational, Scientific and Cultural Organization (UNESCO) implemented a multiyear project to work with the leadership of Iraqi higher education to help update…

  7. Reforming Iraqi Journalism and Mass Communication Higher Education: Adapting the UNESCO Model Curricula for Journalism Education to Iraqi Higher Education

    Science.gov (United States)

    Pavlik, John V.; Laufer, Peter D.; Burns, David P.; Ataya, Ramzi T.

    2012-01-01

    Journalism and mass communication higher education in Iraq is well established but largely isolated from global developments since the 1970s. In the post-Iraq war period, the United Nations Educational, Scientific and Cultural Organization (UNESCO) implemented a multiyear project to work with the leadership of Iraqi higher education to help update…

  8. Modelling Occupational Stress and Employee Health and Wellbeing in a Chinese Higher Education Institution

    Science.gov (United States)

    Sang, Xiaoli; Teo, Stephen T. T.; Cooper, Cary L.; Bohle, Philip

    2013-01-01

    Extensive change is evident in higher education in the People's Republic of China but there have been few studies of the effect of work stress on wellbeing in the higher education sector. The main aim of this study is to test and refine the ASSET ("An Organizational Stress Screening Tool") model of occupational stress in a sample of 150…

  9. Teaching Higher Order Thinking in the Introductory MIS Course: A Model-Directed Approach

    Science.gov (United States)

    Wang, Shouhong; Wang, Hai

    2011-01-01

    One vision of education evolution is to change the modes of thinking of students. Critical thinking, design thinking, and system thinking are higher order thinking paradigms that are specifically pertinent to business education. A model-directed approach to teaching and learning higher order thinking is proposed. An example of application of the…

  10. Pricing Strategies and Models for the Provision of Digitized Texts in Higher Education.

    Science.gov (United States)

    Hardy, Rachel; Oppenheim, Charles; Rubbert, Iris

    2002-01-01

    Describes research into charging mechanisms for the delivery of digitized texts to higher education students in the United Kingdom and discusses the need for a satisfactory pricing model. Explains the HERON (Higher Education Resources On-Demand) and PELICAN (Pricing Experiment Library Information Cooperative Network) projects and considers…

  11. Teaching Higher Order Thinking in the Introductory MIS Course: A Model-Directed Approach

    Science.gov (United States)

    Wang, Shouhong; Wang, Hai

    2011-01-01

    One vision of education evolution is to change the modes of thinking of students. Critical thinking, design thinking, and system thinking are higher order thinking paradigms that are specifically pertinent to business education. A model-directed approach to teaching and learning higher order thinking is proposed. An example of application of the…

  12. Exploring Conceptual Models for Community Engagement at Higher Education Institutions in South Africa

    Science.gov (United States)

    Bender, Gerda

    2008-01-01

    A critical conceptual analysis of the South African Higher Education context reflects the lack of a structural and functional framework for the conceptualisation of community engagement (CE) in higher education. The purpose of this article is to explore a framework and model for the conceptualisation of CE for a better understanding of community…

  13. The U.S. Community College Model and Vietnam's Higher Education System.

    Science.gov (United States)

    Oliver, Diane

    This paper reports on research conducted to determine if United States' community college model can be applied to higher education systems in developing countries. The author examined Vietnam's higher education system and conducted a case study of Can Tho University (CTU) in the Mekong Delta. First, common characteristics found among community…

  14. Sediment Transport Dynamics in River Networks: A Model for Higher-Water Seasons

    Science.gov (United States)

    Huo, Jie; Wang, Xu-Ming; Hao, Rui; Zhang, Jin-Feng

    A dynamical model is proposed to study sediment transport in river networks in higher-water seasons. The model emphasizes the difference between the sediment-carrying capability of the stream in higher-water seasons and that in lower-water seasons. The dynamics of sediment transport shows some complexities such as the complex dependence of the sediment-carrying capability on sediment concentration, the response of the channel(via erosion or sedimentation) to the changes of discharge.

  15. Facilitating Corporate Entrepreneurship in Public Sector Higher Education Institutions: A Conceptual Model

    Directory of Open Access Journals (Sweden)

    Javed Nayyar Malik

    2012-06-01

    Full Text Available This paper develops a conceptual model of public sector corporate entrepreneurship for the state government higher education institutions. The proposed model is intended to depict the main antecedents that relate to corporate entrepreneurship within the public sector higher education institution  and the impact of corporate entrepreneurship on public sector HEI’s performance, as well as factors influencing its continuous performance.

  16. Greenhouse crop residues: Energy potential and models for the prediction of their higher heating value

    Energy Technology Data Exchange (ETDEWEB)

    Callejon-Ferre, A.J.; Lopez-Martinez, J.A.; Manzano-Agugliaro, F. [Departamento de Ingenieria Rural, Universidad de Almeria, Ctra. Sacramento s/n, La Canada de San Urbano, 04120 Almeria (Spain); Velazquez-Marti, B. [Departamento de Ingenieria Rural y Agroalimentaria, Universidad Politecnica de Valencia, Camino de Vera s/n, 46022 Valencia (Spain)

    2011-02-15

    Almeria, in southeastern Spain, generates some 1,086,261 t year{sup -1} (fresh weight) of greenhouse crop (Cucurbita pepo L., Cucumis sativus L., Solanum melongena L., Solanum lycopersicum L., Phaseoulus vulgaris L., Capsicum annuum L., Citrillus vulgaris Schrad. and Cucumis melo L.) residues. The energy potential of this biomass is unclear. The aim of the present work was to accurately quantify this variable, differentiating between crop species while taking into consideration the area they each occupy. This, however, required the direct analysis of the higher heating value (HHV) of these residues, involving very expensive and therefore not commonly available equipment. Thus, a further aim was to develop models for predicting the HHV of these residues, taking into account variables measured by elemental and/or proximate analysis, thus providing an economically attractive alternative to direct analysis. All the analyses in this work involved the use of worldwide-recognised standards and methods. The total energy potential for these plant residues, as determined by direct analysis, was 1,003,497.49 MW h year{sup -1}. Twenty univariate and multivariate equations were developed to predict the HHV. The R{sup 2} and adjusted R{sup 2} values obtained for the univariate and multivariate models were 0.909 and 0.946 or above respectively. In all cases, the mean absolute percentage error varied between 0.344 and 2.533. These results show that any of these 20 equations could be used to accurately predict the HHV of crop residues. The residues produced by the Almeria greenhouse industry would appear to be an interesting source of renewable energy. (author)

  17. Model emulates human smooth pursuit system producing zero-latency target tracking.

    Science.gov (United States)

    Bahill, A T; McDonald, J D

    1983-01-01

    Humans can overcome the 150 ms time delay of the smooth pursuit eye movement system and track smoothly moving visual targets with zero-latency. Our target-selective adaptive control model can also overcome an inherent time delay and produce zero-latency tracking. No other model or man-made system can do this. Our model is physically realizable and physiologically realistic. The technique used in our model should be useful for analyzing other time-delay systems, such as man-machine systems and robots.

  18. EXAMINING THE MOVEMENTS OF MOBILE NODES IN THE REAL WORLD TO PRODUCE ACCURATE MOBILITY MODELS

    Directory of Open Access Journals (Sweden)

    TANWEER ALAM

    2010-09-01

    Full Text Available All communication occurs through a wireless median in an ad hoc network. Ad hoc networks are dynamically created and maintained by the individual nodes comprising the network. Random Waypoint Mobility Model is a model that includes pause times between changes in destination and speed. To produce a real-world environment within which an ad hoc network can be formed among a set of nodes, there is a need for the development of realistic, generic and comprehensive mobility models. In this paper, we examine the movements of entities in the real world and present the production of mobility model in an ad hoc network.

  19. Is the jet-drive flute model able to produce modulated sounds like Flautas de Chinos ?

    CERN Document Server

    Terrien, Soizic; De La Cuadra, Patricio; Fabre, Benoît

    2014-01-01

    Flautas de chinos - prehispanic chilean flutes played during ritual celebrations in central Chile - are known to produce very particular beating sounds, the so-called sonido rajado. Some previous works have focused on the spectral analysis of these sounds, and on the input impedance of the complex resonator. However, the beating sounds origin remains to be investigated. Throughout this paper, a comparison is provided between the characteristics of both the sound produced by flautas de chinos and a synthesis sound obtained through time-domain simulation of the jet-drive model for flute-like instruments. Jet-drive model appears to be able to produce quasiperiodic sounds similar to sonido rajado. Finally, the analysis of the system dynamics through numerical continuation methods allows to explore the production mechanism of these quasiperiodic regimes.

  20. Polarization of inclusively produced $\\Lambda_{c}$ in a QCD based hybrid model

    CERN Document Server

    Goldstein, G R

    1999-01-01

    A hybrid model is presented for hadron polarization that is based on perturbative QCD subprocesses and the recombination of polarized quarks to form polarized hadrons. The model, originally applied to polarized $\\Lambda$'s that were inclusively produced by proton beams, is extended to include pion beams and polarized $\\Lambda_c$'s. The resulting polarizations are calculated as functions of $x_F$ and $p_T$ for high energies and are found to be in fair agreement with recent experiments.

  1. MONITORING AND MODELLING OF AIR POLLUTION PRODUCED BY AIRCRAFT ENGINE EMISSION INSIDE THE ATHENS INTERNATIONAL AIRPORT

    Directory of Open Access Journals (Sweden)

    Oleksander I. Zaporozhets

    2009-04-01

    Full Text Available  Experimental measuring of air pollution inside the airport, produced by aircraft engine emission during accelaration and take-off on the runway. Measurement data were used for verification of modelling results according to complex model «PolEmiCa». It consists of the following basic components: engine emission inventory calculation; transport of the contaminants by engine jets, dispersion of the contaminants in atmosphere due to wind and atmospheric turbulence.

  2. The HTA core model: a novel method for producing and reporting health technology assessments

    DEFF Research Database (Denmark)

    Lampe, Kristian; Mäkelä, Marjukka; Garrido, Marcial Velasco

    2009-01-01

    OBJECTIVES: The aim of this study was to develop and test a generic framework to enable international collaboration for producing and sharing results of health technology assessments (HTAs). METHODS: Ten international teams constructed the HTA Core Model, dividing information contained in a compr...

  3. On modeling micro-structural evolution using a higher order strain gradient continuum theory

    DEFF Research Database (Denmark)

    El-Naaman, S. A.; Nielsen, K. L.; Niordson, C. F.

    2016-01-01

    Published experimental measurements on deformed metal crystals show distinct pattern formation, in which dislocations are arranged in wall and cell structures. The distribution of dislocations is highly non-uniform, which produces discontinuities in the lattice rotations. Modeling the experimenta......Published experimental measurements on deformed metal crystals show distinct pattern formation, in which dislocations are arranged in wall and cell structures. The distribution of dislocations is highly non-uniform, which produces discontinuities in the lattice rotations. Modeling...... a proper treatment of the back stress enables dislocation wall and cell structure type response in the adopted framework....

  4. Intraperitoneal Administration of Low Dose Aluminium in The Rat: How Good is It to Produce a Model for Alzheimer Disease.

    Science.gov (United States)

    Ulusoy, H B; Sonmez, M F; Kilic, E; Caliskan, K; Karaca, B; Kara, M; Ercal, O; Gunduz, Y; Karabulut, D; Bitiktas, S; Tan, B; Kavraal, S; İnal, A; Suer, C

    2015-12-01

    Since neurotoxicity of aluminium (Al) resembles the progressive neurodegeneration observed in Alzheimer Disease (AD), Al administration in several ways has been used to produce AD model. Intraperitoneal (ip) low dose (4.2 mg/ kg) Al injection in rats for long periods is the preferred method by some researchers. In this paper, the efficiency of this method for producing an AD model was evaluated. In this study, we looked at the neuropathology of Al and the characteristic lesions of AD by histological and immunohistochemical techniques and determined oxidative stress markers in the brains of Al-treated and control rats. We also made electrophysiological recordings at the hippocampus and evaluated possible behavioural changes by Morris water maze test. However, no pathologic changes occurred in the animals except for an impairment in long-term potentiation (LTP) in the hippocampus (e.g. the LTPs of population spike (PS) amplitude at 15 min post-tetanus were measured as 217±27% in Al-treated rats and as 240±42% in sham-treated rats, of baseline PS amplitude). According to the findings of the present study, low dose of ip Al in rats is not sufficient to produce a good AD model. Higher doses (≥10 mg/kg) should be used.

  5. Filament-producing mutants of influenza A/Puerto Rico/8/1934 (H1N1 virus have higher neuraminidase activities than the spherical wild-type.

    Directory of Open Access Journals (Sweden)

    Jill Seladi-Schulman

    Full Text Available Influenza virus exhibits two morphologies - spherical and filamentous. Strains that have been grown extensively in laboratory substrates are comprised predominantly of spherical virions while clinical or low passage isolates produce a mixture of spheres and filamentous virions of varying lengths. The filamentous morphology can be lost upon continued passage in embryonated chicken eggs, a common laboratory substrate for influenza viruses. The fact that the filamentous morphology is maintained in nature but lost in favor of a spherical morphology in ovo suggests that filaments confer a selective advantage within the infected host that is not necessary for growth in laboratory substrates. Indeed, we have recently shown that filament-producing variant viruses are selected upon passage of the spherical laboratory strain A/Puerto Rico/8/1934 (H1N1 [PR8] in guinea pigs. Toward determining the nature of the selective advantage conferred by filaments, we sought to identify functional differences between spherical and filamentous particles. We compared the wild-type PR8 virus to two previously characterized recombinant PR8 viruses in which single point mutations within M1 confer a filamentous morphology. Our results indicate that these filamentous PR8 mutants have higher neuraminidase activities than the spherical PR8 virus. Conversely, no differences were observed in HAU:PFU or HAU:RNA ratios, binding avidity, sensitivity to immune serum in hemagglutination inhibition assays, or virion stability at elevated temperatures. Based on these results, we propose that the pleomorphic nature of influenza virus particles is important for the optimization of neuraminidase functions in vivo.

  6. Filament-Producing Mutants of Influenza A/Puerto Rico/8/1934 (H1N1) Virus Have Higher Neuraminidase Activities than the Spherical Wild-Type

    Science.gov (United States)

    Seladi-Schulman, Jill; Campbell, Patricia J.; Suppiah, Suganthi; Steel, John; Lowen, Anice C.

    2014-01-01

    Influenza virus exhibits two morphologies – spherical and filamentous. Strains that have been grown extensively in laboratory substrates are comprised predominantly of spherical virions while clinical or low passage isolates produce a mixture of spheres and filamentous virions of varying lengths. The filamentous morphology can be lost upon continued passage in embryonated chicken eggs, a common laboratory substrate for influenza viruses. The fact that the filamentous morphology is maintained in nature but lost in favor of a spherical morphology in ovo suggests that filaments confer a selective advantage within the infected host that is not necessary for growth in laboratory substrates. Indeed, we have recently shown that filament-producing variant viruses are selected upon passage of the spherical laboratory strain A/Puerto Rico/8/1934 (H1N1) [PR8] in guinea pigs. Toward determining the nature of the selective advantage conferred by filaments, we sought to identify functional differences between spherical and filamentous particles. We compared the wild-type PR8 virus to two previously characterized recombinant PR8 viruses in which single point mutations within M1 confer a filamentous morphology. Our results indicate that these filamentous PR8 mutants have higher neuraminidase activities than the spherical PR8 virus. Conversely, no differences were observed in HAU:PFU or HAU:RNA ratios, binding avidity, sensitivity to immune serum in hemagglutination inhibition assays, or virion stability at elevated temperatures. Based on these results, we propose that the pleomorphic nature of influenza virus particles is important for the optimization of neuraminidase functions in vivo. PMID:25383873

  7. A Model for the Branding of Higher Education in South Africa

    Science.gov (United States)

    Hay, H. R.; van Gensen, G. A.

    2008-01-01

    In this article a proposed model for the branding of higher education institutions is provided. The model describes, among others, the internal practices that have a profound impact on branding and on an institution's overall reputation and image. The authors argue that a strong internal focus is necessary before a meaningful brand experience can…

  8. Measuring Service Quality in Higher Education: Development of a Hierarchical Model (HESQUAL)

    Science.gov (United States)

    Teeroovengadum, Viraiyan; Kamalanabhan, T. J.; Seebaluck, Ashley Keshwar

    2016-01-01

    Purpose: This paper aims to develop and empirically test a hierarchical model for measuring service quality in higher education. Design/methodology/approach: The first phase of the study consisted of qualitative research methods and a comprehensive literature review, which allowed the development of a conceptual model comprising 53 service quality…

  9. A Model for the Branding of Higher Education in South Africa

    Science.gov (United States)

    Hay, H. R.; van Gensen, G. A.

    2008-01-01

    In this article a proposed model for the branding of higher education institutions is provided. The model describes, among others, the internal practices that have a profound impact on branding and on an institution's overall reputation and image. The authors argue that a strong internal focus is necessary before a meaningful brand experience can…

  10. Measuring Service Quality in Higher Education: Development of a Hierarchical Model (HESQUAL)

    Science.gov (United States)

    Teeroovengadum, Viraiyan; Kamalanabhan, T. J.; Seebaluck, Ashley Keshwar

    2016-01-01

    Purpose: This paper aims to develop and empirically test a hierarchical model for measuring service quality in higher education. Design/methodology/approach: The first phase of the study consisted of qualitative research methods and a comprehensive literature review, which allowed the development of a conceptual model comprising 53 service quality…

  11. Higher-Order Markov Tag-Topic Models for Tagged Documents and Images

    CERN Document Server

    Zeng, Jia; Cheung, William K; Li, Chun-Hung

    2011-01-01

    This paper studies the topic modeling problem of tagged documents and images. Higher-order relations among tagged documents and images are major and ubiquitous characteristics, and play positive roles in extracting reliable and interpretable topics. In this paper, we propose the tag-topic models (TTM) to depict such higher-order topic structural dependencies within the Markov random field (MRF) framework. First, we use the novel factor graph representation of latent Dirichlet allocation (LDA)-based topic models from the MRF perspective, and present an efficient loopy belief propagation (BP) algorithm for approximate inference and parameter estimation. Second, we propose the factor hypergraph representation of TTM, and focus on both pairwise and higher-order relation modeling among tagged documents and images. Efficient loopy BP algorithm is developed to learn TTM, which encourages the topic labeling smoothness among tagged documents and images. Extensive experimental results confirm the incorporation of highe...

  12. Benchmark experiments for higher-order and full-Stokes ice sheet models (ISMIP–HOM

    Directory of Open Access Journals (Sweden)

    F. Pattyn

    2008-08-01

    Full Text Available We present the results of the first ice sheet model intercomparison project for higher-order and full-Stokes ice sheet models. These models are compared and verified in a series of six experiments of which one has an analytical solution obtained from a perturbation analysis. The experiments are applied to both 2-D and 3-D geometries; five experiments are steady-state diagnostic, and one has a time-dependent prognostic solution. All participating models give results that are in close agreement. A clear distinction can be made between higher-order models and those that solve the full system of equations. The full-Stokes models show a much smaller spread, hence are in better agreement with one another and with the analytical solution.

  13. Transverse momentum spectra of the produced hadrons at SPS energy and a random walk model

    Indian Academy of Sciences (India)

    Bedangadas Mohanty

    2014-05-01

    The transverse momentum spectra of the produced hadrons have been compared to a model, which is based on the assumption that a nucleus–nucleus collision is a superposition of isotropically decaying thermal sources at a given freeze-out temperature. The freeze-out temperature in nucleus–nucleus collisions is fixed from the inverse slope of the transverse momentum spectra of hadrons in nucleon–nucleon collision. The successive collisions in the nuclear reaction lead to gain in transverse momentum, as the nucleons propagate in the nucleus following a random walk pattern. The average transverse rapidity shift per collision is determined from the nucleon–nucleus collision data. Using this information, we obtain parameter-free result for the transverse momentum distribution of produced hadrons in nucleus–nucleus collisions. It is observed that such a model is able to explain the transverse mass spectra of the produced pions at SPS energies. However, it fails to satisfactorily explain the transverse mass spectra of kaons and protons. This indicates the presence of collective effect which cannot be accounted for, by the initial state collision broadening of transverse momentum of produced hadrons, the basis of random walk model.

  14. Search for the Standard Model Higgs Boson Produced in Association with Top Quarks

    Energy Technology Data Exchange (ETDEWEB)

    Wilson, Jonathan Samuel [Ohio State U.

    2011-01-01

    We have performed a search for the Standard Model Higgs boson produced in association with top quarks in the lepton plus jets channel. We impose no constraints on the decay of the Higgs boson. We employ ensembles of neural networks to discriminate events containing a Higgs boson from the dominant tt¯background, and set upper bounds on the Higgs production cross section. At a Higgs boson mass mH = 120 GeV/c2 , we expect to exclude a cross section 12.7 times the Standard Model prediction, and we observe an exclusion 27.4 times the Standard Model prediction with 95 % confidence.

  15. Generating dynamic higher-order Markov models in web usage mining

    OpenAIRE

    Borges, J; Levene, Mark

    2005-01-01

    Markov models have been widely used for modelling users’ web navigation behaviour. In previous work we have presented a dynamic clustering-based Markov model that accurately represents second-order transition probabilities given by a collection of navigation sessions. Herein, we propose a generalisation of the method that takes into account higher-order conditional probabilities. The method makes use of the state cloning concept together with a clustering technique to separate the navigation ...

  16. Humanism model of education on a physical culture in the institute of higher education

    Directory of Open Access Journals (Sweden)

    Strel'tsov V.A.

    2010-06-01

    Full Text Available Humanistic approach to the modeling of educational process in physical training at the institute of higher education is exposed in the article. The article defines new contents of key categories aimed at transformation of pedagogical consciousness and practice. The article positions the integrity of the student's physical culture formation as the basis of the humanistic-oriented model of education. The realization of the given model shows improved results of students' personality development in comparison with the traditional technocratic approach.

  17. Use of simulation models to study the dynamic of recall of non-conform perishable produce through the supply chain

    DEFF Research Database (Denmark)

    Busato, P.; Sopegno, A.; Berruto, R.

    2013-01-01

    together to form a large size lot at some points in the supply-chain. Larger lot size could imply higher risk for the consumers in case of recall of the produce and much higher recall time and cost for the supply-chain. When a non-conformity occurs, the time to recall the produce depends on many factors...

  18. Memory B cells from older people express normal levels of cyclooxygenase-2 and produce higher levels of IL-6 and IL-10 upon in vitro activation.

    Science.gov (United States)

    Bancos, Simona; Phipps, Richard P

    2010-01-01

    Worldwide the elderly population is increasing. The elderly show deficiencies in immune function. B lymphocytes are essential elements of the immune system responsible for antibody production. This laboratory previously showed that activated human B cells isolated from young adults express cyclooxygenase-2 (Cox-2) and that Cox-2 is essential for optimal antibody responses. Recent data suggests that Cox-2 expression decreases with age in mouse bone tissue. There is no information regarding Cox-2 expression in B cells from older human subjects. We investigated the expression and activity of Cox-2 in naïve and memory B cells from older people. We show that B cells from older subjects show similar Cox-2 protein expression and activity, antibody production and proliferation compared to younger people. However, we found that activated memory B cells from older people produce higher levels of IL-6 and IL-10 compared to young adults. Therefore, the dysregulated cytokine production could contribute to immune senescence in the elderly.

  19. Do Fractal Models of Clouds Produces the Right 3D Radiative Effects?

    Science.gov (United States)

    Varnai, Tamas; Marshak, Alexander; Einaudi, Franco (Technical Monitor)

    2001-01-01

    Stochastic fractal models of clouds are often used to study 3D radiative effects and their influence on the remote sensing of cloud properties. Since it is important that the cloud models produce a correct radiative response, some researchers require the model parameters to match observed cloud properties such as scale-independent optical thickness variability. Unfortunately, matching these properties does not necessarily imply that the cloud models will cause the right 3D radiative effects. First, the matched properties alone only influence the 3D effects but do not completely determine them. Second, in many cases the retrieved cloud properties have been already biased by 3D radiative effects, and so the models may not match the true real clouds. Finally, the matched cloud properties cannot be considered independent from the scales at which they have been retrieved. This paper proposes an approach that helps ensure that fractal cloud models are realistic and produce the right 3D effects. The technique compares the results of radiative transfer simulations for the model clouds to new direct observations of 3D radiative effects in satellite images.

  20. Channel Flow Model of Extrusion of the Higher Himalaya- Successes & Limitations

    Science.gov (United States)

    Mukherjee, S.

    2009-04-01

    During laminar ‘channel flow'/‘Plane Poiseuille flow' of an incompressible Newtonian viscous fluid through a very long parallel horizontal static walls of a channel due to a pressure gradient, a parabolic velocity profile is produced. The sense of ductile shearing across the middle of the channel is opposite. Grujic et al. (1996) and Beaumont et al. (2001) applied this flow mechanism to explain the extrusion of the Higher Himalaya (HH). In their sequel, the Dalhousie school of modelers kept enumerating this extrusion model. Successes of the channel flow extrusion model are that it explains (1) extensional top-to-NE sense of ductile shearing in the South Tibetan Detachment System (STDS) simultaneous to the top-to-SW sense of compressional shearing in the remainder of the HH; (2) fluid activity below the southern part of the Tibetan plateau; and (3) inverted metamorphism in the HH. However, limitations of this extrusion model are as follows. (1) A previous top-to-SW sense of compressional shearing in the STDS is not taken care by the model alone. (2) The thickness of the STDS in reality is thinner than the remainder of the HH. In the model, on the other hand, their thicknesses should be the same. (3) Presence of a second strand of the STDS inside the HH that is absent in some sections of the mountain chain remained unexplained in the model. (4) The ductile shear fabric of more commonly sigmoid-, and less commonly parallelogram- and lenticular geometries are found inside the HH. However, had the channel flow been the extrusion mechanism and rocks deformed as a Newtonian fluid, parabolic shear fabrics are expected. Additionally, can the genesis of the intrafolial folds inside the two strands of the STDS (e.g. Mukherjee, 2007) be explained by the channel flow mechanism? (5) Regions and their spatial extents with different senses of ductile shearing would change if the rocks deformed Non-Newtonically. The exact geometry of the velocity profile will depend on the

  1. A Study of Low Cloud Climate Feedbacks Using a Generalized Higher-Order Closure Subgrid Model

    Science.gov (United States)

    Firl, Grant J.

    One of the biggest uncertainties in projections of future climate is whether and how low cloudiness will change and whether that change will feed back on the climate system. Much of the uncertainty revolves around the difference in scales between the processes that govern low cloudiness and the processes that can be resolved in climate models, a fact that relegates shallow convection to the parameterization realm with varying levels of success. A new subgrid-scale parameterization, named THOR, has been developed in an effort to improve the representation of low cloudiness via parameterization in climate models. THOR uses the higher-order closure approach to determine the statistics describing subgrid-scale processes. These statistics are used to determine a trivariate double-Gaussian PDF among vertical velocity, ice-liquid water potential temperature, and total water specific humidity. With this information, one can diagnose what portion of the grid cell is cloudy, subgrid-scale cloud water content, and subgrid-scale vertical cloud water flux. In addition, samples are drawn from the trivariate PDF in order to drive the microphysics and radiation schemes. Although schemes similar to THOR have been developed over the past decade, THOR includes several novel concepts, like the generalization of the saturation curve to include condensation over both ice and liquid substrates, the determination of the PDF parameters from the given turbulence statistics, the introduction of a stochastic parcel entrainment process for the turbulence length scale, and a sub-column approach for calculating radiative transfer using the PDF. The new model is validated by simulating five test cases spanning a wide range of boundary layer cloud types, from stratocumulus to cumulus and the transition between the two. The results are compared to an ensemble of LES models running the same cases, with particular attention paid to turbulence statistics and cloud structure. For all cloud types tested

  2. Discussion on the teaching mode of higher vocational nursing specialty based on CDIO model

    Directory of Open Access Journals (Sweden)

    Xiu-fang CAI

    2013-11-01

    Full Text Available Discussion on the teaching mode of higher vocational nursing specialty based on CDIO model is the core of this study. CDIO is the latest achievement in the reform of the international higher education of engineering and has been thrived since 2000. There are some inevitable problems when domestic universities introduced and innovated the CDIO mode. Therefore the CDIO model is a bold attempt for the institutions of higher education, especially higher vocational college teachers. The CDIO mode drives teachers to reflect on the existed teaching philosophy, and therefore enables them to change teaching methods in the teaching process and improve their teaching capacity tremendously. Meanwhile, it also encourages students to learn automatically and cultivate their comprehensive abilities such as professional capability, development capability, interpersonal skills, innovation ability, etc.

  3. Benchmark experiments for higher-order and full Stokes ice sheet models (ISMIP-HOM

    Directory of Open Access Journals (Sweden)

    F. Pattyn

    2008-02-01

    Full Text Available We present the results of the first ice sheet model intercomparison project for higher-order and full Stokes ice sheet models. These models are validated in a series of six benchmark experiments of which one has an analytical solution under simplifying assumptions. Five of the tests are diagnostic and one experiment is prognostic or time dependent, for both 2-D and 3-D geometries. The results show a good convergence of the different models even for high aspect ratios. A clear distinction can be made between higher-order models and those that solve the full system of equations. The latter show a significantly better agreement with each other as well as with analytical solutions, which demonstrates that they are hardly influenced by the used numerics.

  4. a Global Shear Velocity Model of the Upper Mantle from New Fundamental and Higher Rayleigh Mode Measurements

    Science.gov (United States)

    Debayle, E.; Ricard, Y. R.

    2011-12-01

    We present a global SV-wave tomographic model of the upper mantle, built from a new dataset of fundamental and higher mode Rayleigh waveforms. We use an extension of the automated waveform inversion approach of Debayle (1999) designed to improve the extraction of fundamental and higher mode information from a single surface wave seismogram. The improvement is shown to be significant in the transition zone structure which is constrained by the higher modes. The new approach is fully automated and can be run on a Beowulf computer to process massive surface wave dataset. It has been used to match successfully over 350 000 fundamental and higher mode Rayleigh waveforms, corresponding to about 20 millions of new measurements extracted from the seismograms. For each seismogram, we obtain a path average shear velocity and quality factor model, and a set of fundamental and higher mode dispersion and attenuation curves compatible with the recorded waveform. The set of dispersion curves provides a global database for future finite frequency inversion. Our new 3D SV-wave tomographic model takes into account the effect of azimuthal anisotropy and is constrained with a lateral resolution of several hundred kilometers and a vertical resolution of a few tens of kilometers. In the uppermost 200 km, our model shows a very strong correlation with surface tectonics. The slow velocity signature of mid-oceanic ridges extend down to ~100 km depth while the high velocity signature of cratons vanishes below 200 km depth. At depth greater than 400 km, the pattern of seismic velocities appear relatively homogeneous at large scale, except for high velocity slabs which produce broad high velocity regions within the transition zone. Although resolution is still good, the region between 200 and 400 km is associated with a complex pattern of seismic heterogeneities showing no simple correlation with the shallower or deeper structure.

  5. Higher Order Mean Squared Error of Generalized Method of Moments Estimators for Nonlinear Models

    Directory of Open Access Journals (Sweden)

    Yi Hu

    2014-01-01

    Full Text Available Generalized method of moments (GMM has been widely applied for estimation of nonlinear models in economics and finance. Although generalized method of moments has good asymptotic properties under fairly moderate regularity conditions, its finite sample performance is not very well. In order to improve the finite sample performance of generalized method of moments estimators, this paper studies higher-order mean squared error of two-step efficient generalized method of moments estimators for nonlinear models. Specially, we consider a general nonlinear regression model with endogeneity and derive the higher-order asymptotic mean square error for two-step efficient generalized method of moments estimator for this model using iterative techniques and higher-order asymptotic theories. Our theoretical results allow the number of moments to grow with sample size, and are suitable for general moment restriction models, which contains conditional moment restriction models as special cases. The higher-order mean square error can be used to compare different estimators and to construct the selection criteria for improving estimator’s finite sample performance.

  6. Impacts of supersymmetric higher derivative terms on inflation models in supergravity

    Energy Technology Data Exchange (ETDEWEB)

    Aoki, Shuntaro; Yamada, Yusuke [Department of Physics, Waseda University,Tokyo 169-8555 (Japan)

    2015-07-14

    We show the effects of supersymmetric higher derivative terms on inflation models in supergravity. The results show that such terms generically modify the effective kinetic coefficient of the inflaton during inflation if the cut off scale of the higher derivative operators is sufficiently small. In such a case, the η-problem in supergravity does not occur, and we find that the effective potential of the inflaton generically becomes a power type potential with a power smaller than two.

  7. Quantum Hall effect in higher dimensions, matrix models and fuzzy geometry

    Energy Technology Data Exchange (ETDEWEB)

    Karabali, D [Department of Physics and Astronomy, Lehman College of the CUNY, Bronx, NY 10468 (United States); Nair, V P [Physics Department, City College of the CUNY, New York, NY 10031 (United States)

    2006-10-13

    We give a brief review of the quantum Hall effect in higher dimensions and its relation to fuzzy spaces. For a quantum Hall system, the lowest Landau level dynamics is given by a one-dimensional matrix action whose large N limit produces an effective action describing the gauge interactions of a higher dimensional quantum Hall droplet. The bulk action is a Chern-Simons type term whose anomaly is exactly cancelled by the boundary action given in terms of a chiral, gauged Wess-Zumino-Witten theory suitably generalized to higher dimensions. We argue that the gauge fields in the Chern-Simons action can be understood as parametrizing the different ways in which the large N limit of the matrix theory is taken. The possible relevance of these ideas to fuzzy gravity is explained. Other applications are also briefly discussed.

  8. Proximate analysis based multiple regression models for higher heating value estimation of low rank coals

    Energy Technology Data Exchange (ETDEWEB)

    Akkaya, Ali Volkan [Department of Mechanical Engineering, Yildiz Technical University, 34349 Besiktas, Istanbul (Turkey)

    2009-02-15

    In this paper, multiple nonlinear regression models for estimation of higher heating value of coals are developed using proximate analysis data obtained generally from the low rank coal samples as-received basis. In this modeling study, three main model structures depended on the number of proximate analysis parameters, which are named the independent variables, such as moisture, ash, volatile matter and fixed carbon, are firstly categorized. Secondly, sub-model structures with different arrangements of the independent variables are considered. Each sub-model structure is analyzed with a number of model equations in order to find the best fitting model using multiple nonlinear regression method. Based on the results of nonlinear regression analysis, the best model for each sub-structure is determined. Among them, the models giving highest correlation for three main structures are selected. Although the selected all three models predicts HHV rather accurately, the model involving four independent variables provides the most accurate estimation of HHV. Additionally, when the chosen model with four independent variables and a literature model are tested with extra proximate analysis data, it is seen that that the developed model in this study can give more accurate prediction of HHV of coals. It can be concluded that the developed model is effective tool for HHV estimation of low rank coals. (author)

  9. About the triviality of the higher derivative sector in the abelian Lee-Wick model

    CERN Document Server

    Fiorentini, D

    2016-01-01

    Canonical quantization is reviewed here for the Abelian Lee-Wick model by using the Dirac constraints method. New degrees of freedom associated to the (higher derivatives) Lee-Wick ghost are excluded from the (physical) space of observables by a new prescription, based on the Nielsen-type BRST-extended symmetry for the Lee-Wick mass term. We prove that this prescription is nothing but an effective form of implementing the cohomological triviality of the higher-derivative pure sector associated to the existence of a new exclusive higher-derivative BRST symmetry.

  10. Obtain Lower-Dimensional Turbulence Systems from Higher-Dimensional Lax Integrable Models

    Institute of Scientific and Technical Information of China (English)

    LOU Sen-Yue

    2001-01-01

    Taking the well known (1-+l)-dimensional turbulence system,the Korteweg de-Vries Burgers equation,as a special example,we show that some types of lower-dimensional turbulence systems may be derived from some higherdimensional Lax integrable models,say,the (2+1)-dimensional asymmetric Nizhnik-Novikov-Veselov equation.On the other hand,using the Lax pair of the original higher-dimensional integrable model(s),we may obtain higher-dimensional Lax pair(s) for a lower-dimensional turbulence system.``

  11. THE MODEL OF MANAGEMENT OF THE INTERNAL MARKETING OF HIGHER EDUCATION INSTITUTE

    Directory of Open Access Journals (Sweden)

    Yuliya Viktorovna Naurazbaeva

    2015-12-01

    Full Text Available The main purpose of the research is the development of methods and models of management of the internal marketing of a higher education institute based on complex approach that includes strategic management methods and staff marketing and also technologies of Neuro-Linguistic Programming (NLP.Method or methodology of the research. Adapted models and methods of Neuro-Linguistic Programming, strategic management and marketing to management of marketing of the university which are presented as a complex of models that are reveling through the interrelation «external labor-market – higher education institute – internal labor-market».Results:1. The mechanism of management of the internal marketing of higher education institute based on the interrelation «external labor – market – higher education institute – internal labor-market» is offered that assumes solving problem of miscomparison between market conditions, university’s opportunities and demands of an employee of this educational institute.2. Methodical bases of formation of NLP-model that coordinates the requirements of labor collective as internal consumers of the educational service and needs of higher education institute in order to provide high quality services at all stages of creation and realization of an educational service are developed.3. The infological model of construction and choosing the strategy of the internal marketing of educational institute is presented.Practical implications. The received results can be used in practical management of higher education institute when forming the strategy of the internal marketing taking into account the specific features of concrete university.

  12. Harnessing the Power of Information Technology: Open Business Models in Higher Education

    Science.gov (United States)

    Sheets, Robert G.; Crawford, Stephen

    2012-01-01

    Higher education is under enormous pressure to improve outcomes and reduce costs. Information technology can help achieve these goals, but only if it is properly harnessed. This article argues that one key to harnessing information technology is business model innovation that results in more "open" and "unbundled" operations in learning and…

  13. Meta-Analysis in Higher Education: An Illustrative Example Using Hierarchical Linear Modeling

    Science.gov (United States)

    Denson, Nida; Seltzer, Michael H.

    2011-01-01

    The purpose of this article is to provide higher education researchers with an illustrative example of meta-analysis utilizing hierarchical linear modeling (HLM). This article demonstrates the step-by-step process of meta-analysis using a recently-published study examining the effects of curricular and co-curricular diversity activities on racial…

  14. Developing a Sustainable Practical Model of Graduate Employability for Higher Education

    Directory of Open Access Journals (Sweden)

    Ahmed Umar Rufai

    2015-01-01

    Full Text Available The purpose of this paper is to evolve a sustainable practical model of employability skills that is sure to capture relevant learning aspects of a particular occupational discipline to be used as framework for Undergraduate students to develop their employability potentials. The study was conducted in three Universities and Polytechnics each with three multi-national companies. Data were collected using semi-structured interviews. Using purposeful sampling 18 academic staff and 3 professionals representing company employers were selected as the study participants. The study evolved a model that is work-based, explicit in its outcome, fully articulated and realistic in terms of employability skill experiences. The proposed model can be used to establish a common higher education programme or curricula that is work-based and skill experience oriented, that can encourage students in higher education to think about work place learning more explicitly and reflectively, that will in turn help them to develop a broad range of knowledge, skills, attitudes, and values, each of which ultimately contribute in some manner to graduate employability.  The paper is considered a contribution to the evolution and growth of knowledge on the linkage between higher education and workplace, through which the ‘skill gap’ occurring between the demand of employment and the level of educational preparation of graduates can be bridged. Keywords: Employability, Higher Education, Graduates, Model/Framework,   academic staff, Employers/Professionals

  15. Policy Internationalization, National Variety and Governance: Global Models and Network Power in Higher Education States

    Science.gov (United States)

    King, Roger

    2010-01-01

    This article analyzes policy convergence and the adoption of globalizing models by higher education states, a process we describe, following Thatcher (2007), as policy internationalization. This refers to processes found in many policy domains and which increasingly are exemplified in tertiary education systems too. The focus is on governmental…

  16. A competency-based model for training of specialists in vertebrology at higher medical school

    Directory of Open Access Journals (Sweden)

    Norkin I.A.

    2016-06-01

    Full Text Available The field of medicine facing the issues of diagnosis and treatment of spine diseases and injuries requires training of specialists in vertebrology taking into consideration the modern standards of higher professional education and medical care conditions. The article deals with the training of the specialists using a competency-based model

  17. Factors Affecting Higher Order Thinking Skills of Students: A Meta-Analytic Structural Equation Modeling Study

    Science.gov (United States)

    Budsankom, Prayoonsri; Sawangboon, Tatsirin; Damrongpanit, Suntorapot; Chuensirimongkol, Jariya

    2015-01-01

    The purpose of the research is to develop and identify the validity of factors affecting higher order thinking skills (HOTS) of students. The thinking skills can be divided into three types: analytical, critical, and creative thinking. This analysis is done by applying the meta-analytic structural equation modeling (MASEM) based on a database of…

  18. Innovating Our Higher Education Models Based on Experience in UK and USA

    Science.gov (United States)

    Hong, Jun; Chen, Haifeng

    2008-01-01

    Our higher education need to innovate education models and actively connect every member in big social system, for example, enterprises, society and environment. This paper shows some new ideas on innovating educational development based on author's studying experience in UK and in USA.

  19. SUCCESS AND PROGRESS IN HIGHER-EDUCATION : A STRUCTURAL MODEL OF STUDYING

    NARCIS (Netherlands)

    MINNAERT, A; JANSSEN, PJ

    1992-01-01

    In Belgium, the success rates of freshmen in higher education are relatively low. To understand this phenomenon a structural model for indiviaual differences in study success and progress is suggested. Starting from the theory that studying is the integration of thinking and learning on the basis of

  20. Open Learning and Formal Credentialing in Higher Education: Curriculum Models and Institutional Policies

    Science.gov (United States)

    Reushle, Shirley, Ed.; Antonio, Amy, Ed.; Keppell, Mike, Ed.

    2016-01-01

    The discipline of education is a multi-faceted system that must constantly integrate new strategies and procedures to ensure successful learning experiences. Enhancements in education provide learners with greater opportunities for growth and advancement. "Open Learning and Formal Credentialing in Higher Education: Curriculum Models and…

  1. Benchmarking the Higher Education Institutions in Egypt using Composite Index Model

    Directory of Open Access Journals (Sweden)

    Mohamed Rashad M El-Hefnawy

    2014-11-01

    Full Text Available Egypt has the largest and most significant higher education system in the Middle East and North Africa but it had been continuously facing serious and accumulated challenges. The Higher Education Institutions in Egypt are undergoing important changes involving the development of performance, they are implementing strategies to enhance the overall performance of their universities using ICT, but still the gap between what is existing and what is supposed to be for the self-regulation and improvement processes is not entirely clear to face these challenges. The using of strategic comparative analysis model and tools to evaluate the current and future states will affect the overall performance of universities and shape new paradigms in development of Higher Education System (HES, several studies have investigated the evaluation of universities through the development and use of ranking and benchmark systems In this paper, we provide a model to construct unified Composite Index (CI based on a set of SMART indictors emulate the nature of higher education systems in Egypt. The outcomes of the proposed model aim to measure overall performance of universities and provide unified benchmarking method in this context. The model was discussed from theoretical and technical perspectives. Meanwhile, the research study was conducted with 40 professors from 19 renowned universities in Egypt as education domain experts.

  2. Towards a general model of quality assessment in higher education (P175)

    NARCIS (Netherlands)

    van Vught, Franciscus A.; Westerheijden, Donald F.

    1994-01-01

    In this article a number of elements of a general model of quality assessment in higher education are presented. On the one hand these elements are put in a historical context of quality assessment in Medieval universities and, on the other hand, deduced from the recent experiences with quality

  3. Handbook for the Commonwealth of Learning Review and Improvement Model: Making Quality Work in Higher Education

    Science.gov (United States)

    Commonwealth of Learning, 2010

    2010-01-01

    The Commonwealth of Learning Review and Improvement Model (COL RIM) was developed by the Commonwealth of Learning in response to two key drivers: (1) Increased global emphasis on the quality of higher education; and (2) Rising concern about the high cost and uncertain benefits of conventional approaches to external quality assurance. Any…

  4. Compound waves in a higher order nonlinear model of thermoviscous fluids

    DEFF Research Database (Denmark)

    Rønne Rasmussen, Anders; Sørensen, Mads Peter; Gaididei, Yuri B.

    2016-01-01

    A generalized traveling wave ansatz is used to investigate compound shock waves in a higher order nonlinear model of a thermoviscous fluid. The fluid velocity potential is written as a traveling wave plus a linear function of space and time. The latter offers the possibility of predicting...

  5. A first-class approach of higher derivative Maxwell-Chern-Simons-Proca model

    Energy Technology Data Exchange (ETDEWEB)

    Sararu, Silviu-Constantin [University of Craiova, Department of Physics, Craiova (Romania)

    2015-11-15

    The equivalence between a higher derivative extension of Maxwell-Chern-Simons-Proca model and some gauge invariant theories from the point of view of the Hamiltonian path integral quantization in the framework of the gauge-unfixing approach is investigated. The Hamiltonian path integrals of the first-class systems take manifestly Lorentz-covariant forms. (orig.)

  6. Phenomenological Study of Business Models Used to Scale Online Enrollment at Institutions of Higher Education

    Science.gov (United States)

    Williams, Dana E.

    2012-01-01

    The purpose of this qualitative phenomenological study was to explore factors for selecting a business model for scaling online enrollment by institutions of higher education. The goal was to explore the lived experiences of academic industry experts involved in the selection process. The research question for this study was: What were the lived…

  7. Applying Foreign Entry Market Strategies to UK Higher Education Transnational Education Models

    Science.gov (United States)

    Lindsay, Victoria; Antoniou, Christos

    2016-01-01

    We take a multidisciplinary approach mapping the models used by UK higher education (HE) institutions against established international business foreign market entry strategies. We review the conditions in host markets that facilitate market entry and consider how these will determine foreign market entry strategy. We specifically consider four…

  8. Phenomenological Study of Business Models Used to Scale Online Enrollment at Institutions of Higher Education

    Science.gov (United States)

    Williams, Dana E.

    2012-01-01

    The purpose of this qualitative phenomenological study was to explore factors for selecting a business model for scaling online enrollment by institutions of higher education. The goal was to explore the lived experiences of academic industry experts involved in the selection process. The research question for this study was: What were the lived…

  9. A Probabilistic Model of Visual Working Memory: Incorporating Higher Order Regularities into Working Memory Capacity Estimates

    Science.gov (United States)

    Brady, Timothy F.; Tenenbaum, Joshua B.

    2013-01-01

    When remembering a real-world scene, people encode both detailed information about specific objects and higher order information like the overall gist of the scene. However, formal models of change detection, like those used to estimate visual working memory capacity, assume observers encode only a simple memory representation that includes no…

  10. Developing of Indicators of an E-Learning Benchmarking Model for Higher Education Institutions

    Science.gov (United States)

    Sae-Khow, Jirasak

    2014-01-01

    This study was the development of e-learning indicators used as an e-learning benchmarking model for higher education institutes. Specifically, it aimed to: 1) synthesize the e-learning indicators; 2) examine content validity by specialists; and 3) explore appropriateness of the e-learning indicators. Review of related literature included…

  11. Expenditures, Efficiency, and Effectiveness in U.S. Undergraduate Higher Education: A National Benchmark Model

    Science.gov (United States)

    Powell, Brett A.; Gilleland, Diane Suitt; Pearson, L. Carolyn

    2012-01-01

    Institutions of higher education are under pressure to be accountable for their expenditures while demonstrating their effectiveness. Through structural equation modeling, a relationship was found between expenditures and the efficiency and effectiveness of an institution, and an optimal expenditure level was found that maximized an institution's…

  12. Meta-Analysis in Higher Education: An Illustrative Example Using Hierarchical Linear Modeling

    Science.gov (United States)

    Denson, Nida; Seltzer, Michael H.

    2011-01-01

    The purpose of this article is to provide higher education researchers with an illustrative example of meta-analysis utilizing hierarchical linear modeling (HLM). This article demonstrates the step-by-step process of meta-analysis using a recently-published study examining the effects of curricular and co-curricular diversity activities on racial…

  13. On the decay of higher order derivatives of solutions to Ladyzhenskaya model for incompressible viscous flows

    Institute of Scientific and Technical Information of China (English)

    DONG BoQing; JIANG Wei

    2008-01-01

    This article concerns large time behavior of Ladyzhenskaya model for incompressible viscous flows in R3. Based on linear Lp-Lq estimates, the auxiliary decay properties of the solutions and generalized Gronwall type arguments, some optimal upper and lower bounds for the decay of higher order derivatives of solutions are derived without assuming any decay properties of solutions and using Fourier splitting technology.

  14. Comparing higher order models for the EORTC QLQ-C30

    NARCIS (Netherlands)

    Gundy, C.M.; Fayers, P.M.; Groenvold, M.; Petersen, M.A.; Scott, N.W.; Sprangers, M.A.G.; Velikova, G.; Aaronson, N.K.

    2012-01-01

    Purpose To investigate the statistical fit of alternative higher order models for summarizing the health-related quality of life profile generated by the EORTC QLQ-C30 questionnaire. Methods A 50% random sample was drawn from a dataset of more than 9,000 pre-treatment QLQ-C30 v 3.0 questionnaires co

  15. Flexible Programmes in Higher Professional Education: Expert Validation of a Flexible Educational Model

    Science.gov (United States)

    Schellekens, Ad; Paas, Fred; Verbraeck, Alexander; van Merrienboer, Jeroen J. G.

    2010-01-01

    In a preceding case study, a process-focused demand-driven approach for organising flexible educational programmes in higher professional education (HPE) was developed. Operations management and instructional design contributed to designing a flexible educational model by means of discrete-event simulation. Educational experts validated the model…

  16. Towards a Multi-Stakeholder-Driven Model for Excellence in Higher Education Curriculum Development

    Science.gov (United States)

    Meyer, M. H.; Bushney, M. J.

    2008-01-01

    A multi-stakeholder-driven model for excellence in higher education curriculum development has been developed. It is based on the assumption that current efforts to curriculum development take place within a framework of limited stakeholder consultation. A total of 18 multiple stakeholders are identified, including learners, alumni, government,…

  17. The Georgia Higher Education Consortium: A Model for Linking Early Intervention Faculty.

    Science.gov (United States)

    Gallagher, Peggy A.; Vail, Cynthia O.; McCormick, Katherine; Malone, D. Michael

    2001-01-01

    A higher education consortium (HEC) in early intervention (EI) is described. An evaluation of the model found that benefits to faculty of HEC participation included development and implementation of EI coursework, development of interdisciplinary collaborative relationships, increased knowledge of state resources, and enhanced knowledge of EI…

  18. Harnessing the Power of Information Technology: Open Business Models in Higher Education

    Science.gov (United States)

    Sheets, Robert G.; Crawford, Stephen

    2012-01-01

    Higher education is under enormous pressure to improve outcomes and reduce costs. Information technology can help achieve these goals, but only if it is properly harnessed. This article argues that one key to harnessing information technology is business model innovation that results in more "open" and "unbundled" operations in learning and…

  19. Longitudinal Data Analysis with Latent Growth Modeling: An Introduction and Illustration for Higher Education Researchers

    Science.gov (United States)

    Blanchard, Rebecca D.; Konold, Timothy R.

    2011-01-01

    This paper introduces latent growth modeling (LGM) as a statistical method for analyzing change over time in latent, or unobserved, variables, with particular emphasis of the application of this method in higher education research. While increasingly popular in other areas of education research and despite a wealth of publicly-available datasets…

  20. Collective Academic Supervision: A Model for Participation and Learning in Higher Education

    Science.gov (United States)

    Nordentoft, Helle Merete; Thomsen, Rie; Wichmann-Hansen, Gitte

    2013-01-01

    Supervision of graduate students is a core activity in higher education. Previous research on graduate supervision focuses on individual and relational aspects of the supervisory relationship rather than collective, pedagogical and methodological aspects of the supervision process. In presenting a collective model we have developed for academic…

  1. Towards a Multi-Stakeholder-Driven Model for Excellence in Higher Education Curriculum Development

    Science.gov (United States)

    Meyer, M. H.; Bushney, M. J.

    2008-01-01

    A multi-stakeholder-driven model for excellence in higher education curriculum development has been developed. It is based on the assumption that current efforts to curriculum development take place within a framework of limited stakeholder consultation. A total of 18 multiple stakeholders are identified, including learners, alumni, government,…

  2. Innovation Diffusion Model in Higher Education: Case Study of E-Learning Diffusion

    Science.gov (United States)

    Buc, Sanjana; Divjak, Blaženka

    2015-01-01

    The diffusion of innovation (DOI) is critical for any organization and especially nowadays for higher education institutions (HEIs) in the light of vast pressure of emerging educational technologies as well as of the demand of economy and society. DOI takes into account the initial and the implementation phase. The conceptual model of DOI in…

  3. Mathematical Modeling of Surface Roughness of Castings Produced Using ZCast Direct Metal Casting

    Science.gov (United States)

    Chhabra, M.; Singh, R.

    2015-04-01

    Aim of this investigation is to develop a mathematical model for predicting surface roughness of castings produced using ZCast process by employing Buckingham's π-theorem. A relationship has been proposed between surface roughness of castings and shell wall thickness of the shell moulds fabricated using 3D printer. Based on model, experiments were performed to obtain the surface roughness of aluminium, brass and copper castings produced using ZCast process based on 3D printing technique. Based on experimental data, three best fitted third-degree polynomial equations have been established for predicting the surface roughness of castings. The predicted surface roughness values were then calculated using established best fitted equations. An error analysis was performed to compare the experimental and predicted data. The average prediction errors obtained for aluminium, brass and copper castings are 10.6, 2.43 and 3.12 % respectively. The obtained average surface roughness (experimental and predicted) values of castings produced are acceptable with the sand cast surface roughness values range (6.25-25 µm).

  4. Role of thyrotropin-releasing hormone in prolactin-producing cell models.

    Science.gov (United States)

    Kanasaki, Haruhiko; Oride, Aki; Mijiddorj, Tselmeg; Kyo, Satoru

    2015-12-01

    Thyrotropin-releasing hormone (TRH) is a hypothalamic hypophysiotropic neuropeptide that was named for its ability to stimulate the release of thyroid-stimulating hormone in mammals. It later became apparent that it exerts a number of species-dependent hypophysiotropic activities that regulate other pituitary hormones. TRH also regulates the synthesis and release of prolactin, although whether it is a physiological regulator of prolactin that remains unclear. Occupation of the Gq protein-coupled TRH receptor in the prolactin-producing lactotroph increases the turnover of inositol, which in turn activates the protein kinase C pathway and the release of Ca(2+) from storage sites. TRH-induced signaling events also include the activation of extracellular signal-regulated kinase (ERK) and induction of MAP kinase phosphatase, an inactivator of activated ERK. TRH stimulates prolactin synthesis through the activation of ERK, whereas prolactin release occurs via elevation of intracellular Ca(2+). We have been investigating the role of TRH in a pituitary prolactin-producing cell model. Rat pituitary somatolactotroph GH3 cells, which produce and release both prolactin and growth hormone (GH), are widely used as a model for the study of prolactin- and GH-secreting cells. In this review, we describe the general action of TRH as a hypophysiotropic factor in vertebrates and focus on the role of TRH in prolactin synthesis using GH3 cells.

  5. Selection of higher order regression models in the analysis of multi-factorial transcription data.

    Directory of Open Access Journals (Sweden)

    Olivia Prazeres da Costa

    Full Text Available INTRODUCTION: Many studies examine gene expression data that has been obtained under the influence of multiple factors, such as genetic background, environmental conditions, or exposure to diseases. The interplay of multiple factors may lead to effect modification and confounding. Higher order linear regression models can account for these effects. We present a new methodology for linear model selection and apply it to microarray data of bone marrow-derived macrophages. This experiment investigates the influence of three variable factors: the genetic background of the mice from which the macrophages were obtained, Yersinia enterocolitica infection (two strains, and a mock control, and treatment/non-treatment with interferon-γ. RESULTS: We set up four different linear regression models in a hierarchical order. We introduce the eruption plot as a new practical tool for model selection complementary to global testing. It visually compares the size and significance of effect estimates between two nested models. Using this methodology we were able to select the most appropriate model by keeping only relevant factors showing additional explanatory power. Application to experimental data allowed us to qualify the interaction of factors as either neutral (no interaction, alleviating (co-occurring effects are weaker than expected from the single effects, or aggravating (stronger than expected. We find a biologically meaningful gene cluster of putative C2TA target genes that appear to be co-regulated with MHC class II genes. CONCLUSIONS: We introduced the eruption plot as a tool for visual model comparison to identify relevant higher order interactions in the analysis of expression data obtained under the influence of multiple factors. We conclude that model selection in higher order linear regression models should generally be performed for the analysis of multi-factorial microarray data.

  6. Modeling the competition between PHA-producing and non-PHA-producing bacteria in feast-famine SBR and staged CSTR systems.

    Science.gov (United States)

    Marang, Leonie; van Loosdrecht, Mark C M; Kleerebezem, Robbert

    2015-12-01

    Although the enrichment of specialized microbial cultures for the production of polyhydroxyalkanoates (PHA) is generally performed in sequencing batch reactors (SBRs), the required feast-famine conditions can also be established using two or more continuous stirred-tank reactors (CSTRs) in series with partial biomass recirculation. The use of CSTRs offers several advantages, but will result in distributed residence times and a less strict separation between feast and famine conditions. The aim of this study was to investigate the impact of the reactor configuration, and various process and biomass-specific parameters, on the enrichment of PHA-producing bacteria. A set of mathematical models was developed to predict the growth of Plasticicumulans acidivorans-as a model PHA producer-in competition with a non-storing heterotroph. A macroscopic model considering lumped biomass and an agent-based model considering individual cells were created to study the effect of residence time distribution and the resulting distributed bacterial states. The simulations showed that in the 2-stage CSTR system the selective pressure for PHA-producing bacteria is significantly lower than in the SBR, and strongly affected by the chosen feast-famine ratio. This is the result of substrate competition based on both the maximum specific substrate uptake rate and substrate affinity. Although the macroscopic model overestimates the selective pressure in the 2-stage CSTR system, it provides a quick and fairly good impression of the reactor performance and the impact of process and biomass-specific parameters.

  7. Spontaneous Polarization of Kondo problem associated with Higher-spin analog of the 6-vertex model

    CERN Document Server

    Fukushima, N

    1999-01-01

    We study Kondo-type model associated with an integrable Higher-spin analog of the 6-vertex mode, which is constructed by inserting a spin 1/2 to spin 1 lines: $... C^3 \\otimes C^3 \\otimes C^2 \\otimes C^3 \\otimes C^3 ... .$ We formulate the problem in terms of representation theory of quantum affine algebra $U_q(\\hat{sl_2})$. We derive an exact formula of the spontaneous staggered polarization for our model, which corresponds to Baxter's formula for the 6-vertex model.

  8. Biomechanical model produced from light-activated dental composite resins: a holographic analysis

    Science.gov (United States)

    Pantelić, Dejan; Vasiljević, Darko; Blažić, Larisa; Savić-Šević, Svetlana; Murić, Branka; Nikolić, Marko

    2013-11-01

    Light-activated dental composites, commonly applied in dentistry, can be used as excellent material for producing biomechanical models. They can be cast in almost any shape in an appropriate silicone mold and quickly solidified by irradiation with light in the blue part of the spectrum. In that way, it is possible to obtain any number of nearly identical casts. The models can be used to study the behavior of arbitrary structure under mechanical loads. To test the technique, a simple mechanical model of the tooth with a mesio-occluso-distal cavity was manufactured. Composite resin restoration was placed inside the cavity and light cured. Real-time holographic interferometry was used to analyze the contraction of the composite resin and its effect on the surrounding material. The results obtained in the holographic experiment were in good agreement with those obtained using the finite element method.

  9. Evaluation and modelling of integral capacitors produced by interdigitated comb electrodes

    Directory of Open Access Journals (Sweden)

    Leandro Alfredo Ramajo

    2008-12-01

    Full Text Available Integral capacitors (IC of one or two-layer printed wiring board (PWB circuits were produced using comb electrodes fixtures and dielectric composites as the inter-electrode material. ICs were fabricated at laboratory scale, using copper comb electrodes and BaTiO3-epoxy composite materials deposited on a glass-Epoxy FR4 board. They were experimentally tested in order to obtain their electrical response. Furthermore, ICs behaviour was modelled through 2-dimensional models applying finite element method (FEM. Results showed that by this laboratory technique it was possible to obtained integral capacitors with low dielectric losses. Moreover, acceptable agreement was found between numerical and experimental capacitance results for all the different analysed ICs. In conclusion, 2D FEM models are a suitable tool to predict electric response of IC devices.

  10. Modeling of wear behavior of Al/B{sub 4}C composites produced by powder metallurgy

    Energy Technology Data Exchange (ETDEWEB)

    Sahin, Ismail; Bektas, Asli [Gazi Univ., Ankara (Turkey). Dept. of Industrial Design Engineering; Guel, Ferhat; Cinci, Hanifi [Gazi Univ., Ankara (Turkey). Dept. of Materials and Metallurgy Engineering

    2017-06-01

    Wear characteristics of composites, Al matrix reinforced with B{sub 4}C particles percentages of 5, 10,15 and 20 produced by the powder metallurgy method were studied in this study. For this purpose, a mixture of Al and B{sub 4}C powders were pressed under 650 MPa pressure and then sintered at 635 C. The analysis of hardness, density and microstructure was performed. The produced samples were worn using a pin-on-disk abrasion device under 10, 20 and 30 N load through 500, 800 and 1200 mesh SiC abrasive papers. The obtained wear values were implemented in an artificial neural network (ANN) model having three inputs and one output using feed forward backpropagation Levenberg-Marquardt algorithm. Thus, the optimum wear conditions and hardness values were determined.

  11. The grounding of higher order concepts in action and language: a cognitive robotics model.

    Science.gov (United States)

    Stramandinoli, Francesca; Marocco, Davide; Cangelosi, Angelo

    2012-08-01

    In this paper we present a neuro-robotic model that uses artificial neural networks for investigating the relations between the development of symbol manipulation capabilities and of sensorimotor knowledge in the humanoid robot iCub. We describe a cognitive robotics model in which the linguistic input provided by the experimenter guides the autonomous organization of the robot's knowledge. In this model, sequences of linguistic inputs lead to the development of higher-order concepts grounded on basic concepts and actions. In particular, we show that higher-order symbolic representations can be indirectly grounded in action primitives directly grounded in sensorimotor experiences. The use of recurrent neural network also permits the learning of higher-order concepts based on temporal sequences of action primitives. Hence, the meaning of a higher-order concept is obtained through the combination of basic sensorimotor knowledge. We argue that such a hierarchical organization of concepts can be a possible account for the acquisition of abstract words in cognitive robots. Copyright © 2012 Elsevier Ltd. All rights reserved.

  12. Classical defects in higher-dimensional Einstein gravity coupled to nonlinear σ -models

    Science.gov (United States)

    Prasetyo, Ilham; Ramadhan, Handhika S.

    2017-09-01

    We construct solutions of higher-dimensional Einstein gravity coupled to nonlinear σ -model with cosmological constant. The σ -model can be perceived as exterior configuration of a spontaneously-broken SO(D-1) global higher-codimensional "monopole". Here we allow the kinetic term of the σ -model to be noncanonical; in particular we specifically study a quadratic-power-law type. This is some possible higher-dimensional generalization of the Bariola-Vilenkin (BV) solutions with k-global monopole studied recently. The solutions can be perceived as the exterior solution of a black hole swallowing up noncanonical global defects. Even in the absence of comological constant its surrounding spacetime is asymptotically non-flat; it suffers from deficit solid angle. We discuss the corresponding horizons. For Λ >0 in 4 d there can exist three extremal conditions (the cold, ultracold, and Nariai black holes), while in higher-than-four dimensions the extremal black hole is only Nariai. For Λ <0 we only have black hole solutions with one horizon, save for the 4 d case where there can exist two horizons. We give constraints on the mass and the symmetry-breaking scale for the existence of all the extremal cases. In addition, we also obtain factorized solutions, whose topology is the direct product of two-dimensional spaces of constant curvature (M_2, dS_2, or AdS_2) with (D-2)-sphere. We study all possible factorized channels.

  13. Simulation of Flash-Flood-Producing Storm Events in Saudi Arabia Using the Weather Research and Forecasting Model

    KAUST Repository

    Deng, Liping

    2015-05-01

    The challenges of monitoring and forecasting flash-flood-producing storm events in data-sparse and arid regions are explored using the Weather Research and Forecasting (WRF) Model (version 3.5) in conjunction with a range of available satellite, in situ, and reanalysis data. Here, we focus on characterizing the initial synoptic features and examining the impact of model parameterization and resolution on the reproduction of a number of flood-producing rainfall events that occurred over the western Saudi Arabian city of Jeddah. Analysis from the European Centre for Medium-Range Weather Forecasts (ECMWF) interim reanalysis (ERA-Interim) data suggests that mesoscale convective systems associated with strong moisture convergence ahead of a trough were the major initial features for the occurrence of these intense rain events. The WRF Model was able to simulate the heavy rainfall, with driving convective processes well characterized by a high-resolution cloud-resolving model. The use of higher (1 km vs 5 km) resolution along the Jeddah coastline favors the simulation of local convective systems and adds value to the simulation of heavy rainfall, especially for deep-convection-related extreme values. At the 5-km resolution, corresponding to an intermediate study domain, simulation without a cumulus scheme led to the formation of deeper convective systems and enhanced rainfall around Jeddah, illustrating the need for careful model scheme selection in this transition resolution. In analysis of multiple nested WRF simulations (25, 5, and 1 km), localized volume and intensity of heavy rainfall together with the duration of rainstorms within the Jeddah catchment area were captured reasonably well, although there was evidence of some displacements of rainstorm events.

  14. Conceptual Foundations of Transition to the Nonlinear Models of Higher Education in the Region

    Directory of Open Access Journals (Sweden)

    Garold Efimovich Zborovsky

    2016-12-01

    Full Text Available The subject matter of the analysis is the non-linear characteristics of the new model of higher education in relation to its resources and risk environment. The purpose of this article is to prove the need and the possibility of transition to the nonlinear model of higher education in the region on the basis of theoretical positions and the results of the study of non-linear socio-economic processes. In this connection, the socio-economic factors of such transition are characterized; the objective necessity of its implementation in the context of the economic and social uncertainty of a particular region, which is Ural Federal District, is shown. A new type of relationship between universities and their social partners is considered. The need for the change of interactions between educational communities; reliance on the use of a new wide range of economic, social and spiritual resources; the constant search for new mechanisms, educational programs, relations with the external environment, management decisions are argued. Ural Federal District is shown as one of the most advanced regions of the Russian Federation not only in the sphere of the economy, social and cultural life, but also in the sphere of higher education. This circumstance is related to the constant, intensive search for innovative approaches to the modernization of higher education in the region, including the formation of its non-linear model. The presented situation forms the basis of the hypothesis that the non-linear model of higher education can ensure its competitiveness in the global educational space, to enhance its role in the society and specific regions of the country and to turn it into a locomotive of the socio-economic and socio-cultural development. The study is based on an interdisciplinary methodology, including the potential of theoretical sociology, sociology of education, economic sociology, management theory, regional economy. The findings of the research

  15. Random matrix theory and higher genus integrability: the quantum chiral Potts model

    Energy Technology Data Exchange (ETDEWEB)

    Angles d' Auriac, J.Ch. [Centre de Recherches sur les Tres Basses Temperatures, BP 166, Grenoble (France)]. E-mail: dauriac@polycnrs-gre.fr; Maillard, J.M.; Viallet, C.M. [LPTHE, Tour 16, Paris (France)]. E-mails: maillard@lpthe.jussieu.fr; viallet@lpthe.jussieu.fr

    2002-06-14

    We perform a random matrix theory (RMT) analysis of the quantum four-state chiral Potts chain for different sizes of the chain up to size L 8. Our analysis gives clear evidence of a Gaussian orthogonal ensemble (GOE) statistics, suggesting the existence of a generalized time-reversal invariance. Furthermore, a change from the (generic) GOE distribution to a Poisson distribution occurs when the integrability conditions are met. The chiral Potts model is known to correspond to a (star-triangle) integrability associated with curves of genus higher than zero or one. Therefore, the RMT analysis can also be seen as a detector of 'higher genus integrability'. (author)

  16. Higher Spin Currents in the Enhanced N=3 Kazama-Suzuki Model

    CERN Document Server

    Ahn, Changhyun

    2016-01-01

    The N=3 Kazama-Suzuki model at the `critical' level has been found by Creutzig, Hikida and Ronne. We construct the lowest higher spin currents of spins (3/2, 2,2,2,5/2, 5/2, 5/2, 3) in terms of various fermions. In order to obtain the operator product expansions (OPEs) between these higher spin currents, we describe three N=2 OPEs between the two N=2 higher spin currents denoted by (3/2, 2, 2, 5/2) and (2, 5/2, 5/2, 3) (corresponding 36 OPEs in the component approach). Using the various Jacobi identities, the coefficient functions appearing on the right hand side of these N=2 OPEs are determined in terms of central charge completely. Then we describe them as one single N=3 OPE in the N=3 superspace. The right hand side of this N=3 OPE contains the SO(3)-singlet N=3 higher spin multiplet of spins (2, 5/2, 5/2, 5/2, 3,3,3, 7/2), the SO(3)-singlet N=3 higher spin multiplet of spins (5/2, 3,3,3, 7/2, 7/2, 7/2, 4), and the SO(3)-triplet N=3 higher spin multiplets where each multiplet has the spins (3, 7/2, 7/2, 7/...

  17. Higher-order QCD predictions for dark matter production at the LHC in simplified models with s-channel mediators

    Energy Technology Data Exchange (ETDEWEB)

    Backović, Mihailo [Centre for Cosmology, Particle Physics and Phenomenology (CP3), Université catholique de Louvain, 1348, Louvain-la-Neuve (Belgium); Krämer, Michael [Institute for Theoretical Particle Physics and Cosmology, RWTH Aachen University, 52056, Aachen (Germany); Maltoni, Fabio; Martini, Antony [Centre for Cosmology, Particle Physics and Phenomenology (CP3), Université catholique de Louvain, 1348, Louvain-la-Neuve (Belgium); Mawatari, Kentarou, E-mail: kentarou.mawatari@vub.ac.be [Theoretische Natuurkunde and IIHE/ELEM, Vrije Universiteit Brussel, and International Solvay Institutes, Pleinlaan 2, 1050, Brussels (Belgium); Pellen, Mathieu [Institute for Theoretical Particle Physics and Cosmology, RWTH Aachen University, 52056, Aachen (Germany)

    2015-10-07

    Weakly interacting dark matter particles can be pair-produced at colliders and detected through signatures featuring missing energy in association with either QCD/EW radiation or heavy quarks. In order to constrain the mass and the couplings to standard model particles, accurate and precise predictions for production cross sections and distributions are of prime importance. In this work, we consider various simplified models with s-channel mediators. We implement such models in the FeynRules/MadGraph5{sub a}MC@NLO framework, which allows to include higher-order QCD corrections in realistic simulations and to study their effect systematically. As a first phenomenological application, we present predictions for dark matter production in association with jets and with a top-quark pair at the LHC, at next-to-leading order accuracy in QCD, including matching/merging to parton showers. Our study shows that higher-order QCD corrections to dark matter production via s-channel mediators have a significant impact not only on total production rates, but also on shapes of distributions. We also show that the inclusion of next-to-leading order effects results in a sizeable reduction of the theoretical uncertainties.

  18. Higher-order QCD predictions for dark matter production at the LHC in simplified models with s-channel mediators

    Energy Technology Data Exchange (ETDEWEB)

    Backovic, Mihailo; Maltoni, Fabio; Martini, Antony [Universite catholique de Louvain, Centre for Cosmology, Particle Physics and Phenomenology (CP3), Louvain-la-Neuve (Belgium); Kraemer, Michael; Pellen, Mathieu [RWTH Aachen University, Institute for Theoretical Particle Physics and Cosmology, Aachen (Germany); Mawatari, Kentarou [Theoretische Natuurkunde and IIHE/ELEM, Vrije Universiteit Brussel, and International Solvay Institutes, Brussels (Belgium)

    2015-10-15

    Weakly interacting dark matter particles can be pair-produced at colliders and detected through signatures featuring missing energy in association with either QCD/EW radiation or heavy quarks. In order to constrain the mass and the couplings to standard model particles, accurate and precise predictions for production cross sections and distributions are of prime importance. In this work, we consider various simplified models with s-channel mediators. We implement such models in the FeynRules/MadGraph5{sub a}MC rate at NLO framework, which allows to include higher-order QCD corrections in realistic simulations and to study their effect systematically. As a first phenomenological application, we present predictions for dark matter production in association with jets and with a top-quark pair at the LHC, at next-to-leading order accuracy in QCD, including matching/merging to parton showers. Our study shows that higher-order QCD corrections to dark matter production via s-channel mediators have a significant impact not only on total production rates, but also on shapes of distributions. We also show that the inclusion of next-to-leading order effects results in a sizeable reduction of the theoretical uncertainties. (orig.)

  19. Higher-order QCD predictions for dark matter production at the LHC in simplified models with s-channel mediators.

    Science.gov (United States)

    Backović, Mihailo; Krämer, Michael; Maltoni, Fabio; Martini, Antony; Mawatari, Kentarou; Pellen, Mathieu

    Weakly interacting dark matter particles can be pair-produced at colliders and detected through signatures featuring missing energy in association with either QCD/EW radiation or heavy quarks. In order to constrain the mass and the couplings to standard model particles, accurate and precise predictions for production cross sections and distributions are of prime importance. In this work, we consider various simplified models with s-channel mediators. We implement such models in the FeynRules/MadGraph5_aMC@NLO framework, which allows to include higher-order QCD corrections in realistic simulations and to study their effect systematically. As a first phenomenological application, we present predictions for dark matter production in association with jets and with a top-quark pair at the LHC, at next-to-leading order accuracy in QCD, including matching/merging to parton showers. Our study shows that higher-order QCD corrections to dark matter production via s-channel mediators have a significant impact not only on total production rates, but also on shapes of distributions. We also show that the inclusion of next-to-leading order effects results in a sizeable reduction of the theoretical uncertainties.

  20. Sphalerons and the Electroweak Phase Transition in Models with Higher Scalar Representations

    CERN Document Server

    Ahriche, Amine; Nasri, Salah

    2014-01-01

    In this work we investigate the sphaleron solution in a $SU(2)\\times U(1)_X$ gauge theory, which also encompasses the Standard Model, with higher scalar representation(s) ($J^{(i)},X^{(i)}$). We show that the field profiles describing the sphaleron in higher scalar multiplet, have similar trends like the doublet case with respect to the radial distance. We compute the sphaleron energy and find that it scales linearly with the vacuum expectation value of the scalar field and its slope depends on the representation. We also investigate the effect of $U(1)$ gauge field and find that it is small for the physical value of the mixing angle, $\\theta_{W}$ and resembles the case for the doublet. For higher representations, we show that the criterion for strong first order phase transition, $v_{c}/T_{c}>\\eta$, is relaxed with respect to the doublet case, i.e. $\\eta<1$.

  1. A reference Earth model for the heat producing elements and associated geoneutrino flux

    CERN Document Server

    Huang, Yu; Mantovani, Fabio; Rudnick, Roberta L; McDonough, William F

    2013-01-01

    The recent geoneutrino experimental results from KamLAND and Borexino detectors reveal the usefulness of analyzing the Earth geoneutrino flux, as it provides a constraint on the strength of the radiogenic heat power and this, in turn, provides a test of compositional models of the bulk silicate Earth (BSE). This flux is dependent on the amount and distribution of heat producing elements (HPEs: U, Th and K) in the Earth interior. We have developed a geophysically-based, three-dimensional global reference model for the abundances and distributions of HPEs in the BSE. The structure and composition of the outermost portion of the Earth, the crust and underlying lithospheric mantle, is detailed in the reference model, this portion of the Earth has the greatest influence on the geoneutrino fluxes. The reference model combines three existing geophysical models of the global crust and yields an average crustal thickness of 34.4+-4.1 km in the continents and 8.0+-2.7 km in the oceans. In situ seismic velocity provided...

  2. Structure and tensile properties evaluation of samples produced by Fused Deposition Modeling

    Science.gov (United States)

    Gajdoš, Ivan; Slota, Ján; Spišák, Emil; Jachowicz, Tomasz; Tor-Swiatek, Aneta

    2016-05-01

    This paper presents the result of a study evaluating the influence of alternative path generation strategy on structure and some mechanical properties of parts produced by Fused Deposition Modeling (FDM) technology. Several scientific investigations focused on resolving issues in FDM parts by modifying a path generation strategy to optimize its mechanical properties. In this study, an alternative strategy was proposed with the intention of minimizing internal voids and, thus, to improve mechanical properties. Polycarbonate samples made by this alternative path generation strategy were subjected to tensile strength test and metro-tomography structure evaluation. The results reveal that the structure observed on build models differs from a structure expected from path generation predicted by software Insight 9.1. This difference affected the tensile strength of samples.

  3. Independent power producer parallel operation modeling in transient network simulations for interconnected distributed generation studies

    Energy Technology Data Exchange (ETDEWEB)

    Moura, Fabricio A.M.; Camacho, Jose R. [Universidade Federal de Uberlandia, School of Electrical Engineering, Rural Electricity and Alternative Sources Lab, PO Box 593, 38400.902 Uberlandia, MG (Brazil); Chaves, Marcelo L.R.; Guimaraes, Geraldo C. [Universidade Federal de Uberlandia, School of Electrical Engineering, Power Systems Dynamics Group, PO Box: 593, 38400.902 Uberlandia, MG (Brazil)

    2010-02-15

    The main task in this paper is to present a performance analysis of a distribution network in the presence of an independent power producer (IP) synchronous generator with its speed governor and voltage regulator modeled using TACS -Transient Analysis of Control Systems, for distributed generation studies. Regulators were implemented through their transfer functions in the S domain. However, since ATP-EMTP (Electromagnetic Transient Program) works in the time domain, a discretization is necessary to return the TACS output to time domain. It must be highlighted that this generator is driven by a steam turbine, and the whole system with regulators and the equivalent of the power authority system at the common coupling point (CCP) are modeled in the ''ATP-EMTP -Alternative Transients Program''. (author)

  4. Network model explains why cancer cells use inefficient pathway to produce energy

    Science.gov (United States)

    Lee, Joo Sang; Marko, John; Motter, Adilson

    2012-02-01

    The Warburg effect---the use of the (energetically inefficient) fermentative pathway as opposed to (energetically efficient) respiration even in the presence of oxygen---is a common property of cancer metabolism. Here, we propose that the Warburg effect is in fact a consequence of a trade-off between the benefit of rapid growth and the cost for protein synthesis. Using genome-scale metabolic networks, we have modeled the cellular resources for protein synthesis as a growth defect that increases with enzyme concentration. Based on our model, we demonstrate that the cost of protein production during rapid growth drives the cell to rely on fermentation to produce ATP. We also identify an intimate link between extensive fermentation and rapid biosynthesis. Our findings emphasize the importance of protein synthesis as a limiting factor on cell proliferation and provide a novel mathematical framework to analyze cancer metabolism.

  5. Using an ‘open approach’ to create a new, innovative higher education model

    Directory of Open Access Journals (Sweden)

    Susan Huggins

    2015-04-01

    Full Text Available Navigating learning, formal or informal, can be overwhelming, confusing, and impersonal. With more options than ever, the process of deciding what, where, and when can be overwhelming to a learner. The concept of Open College at Kaplan University (OC@KU was to bring organization, purpose, and personalization of learning caused by vast resources and numerous options. Focused on organizing, supporting and providing a personalized education experience using open courses, an innovative higher education model was conceived and created. As the concept of developing a college that adapted its resources and services to the needs of the learner emerged so did the idea of integrating open courses into a formal higher education model to award college credit for open courses as well as inclusion in a degree program. http://dx.doi.org/10.5944/openpraxis.7.2.193

  6. Higher spin holography and the AdS string sigma model

    Science.gov (United States)

    Polyakov, Dimitri

    2013-05-01

    We analyse the cubic spin-3 interaction in AdS space using the higher spin extension of the string-theoretic sigma-model constructed in our previous work, whose low energy limit is described by the AdS vacuum solution. We find that, in the leading order of the cosmological constant, the spin-3 correlator on the AdS4 string theory side reproduces the structure of the three-point function of composite operators, quadratic in free fields, in the dual d = 3 vector model. The cancellation of holography violating terms in d = 3 is related to the value of the Liouville background charge in d = 4. This article is part of a special issue of Journal of Physics A: Mathematical and Theoretical devoted to ‘Higher spin theories and holography’.

  7. Creating Sustainable Competitive Advantage thro ugh Reputation Management: A Model Development for Restructuring Higher Education

    Directory of Open Access Journals (Sweden)

    Mesut Öncel

    2014-12-01

    Full Text Available Along with the research that has been carried out in recent years, realizing that the reputation is a measurable value has caused discussions about how to manage reputation. Although reputation management has been studied extensively by different scientists in different disciplines, there is relatively a limited number of study in the field of higher education. The aim of this research is to determine the corporate reputation management of universities at universities scale and develop a model for structuring it in universities within Turkey Higher Education system as an administrative approach. In the light of the gathered data, a model to structure the corporate reputation management for achieving a sustainable competitive strength in Turkish universities has been proposed.

  8. Comparison of QuadrapolarTM radiofrequency lesions produced by standard versus modified technique: an experimental model

    Directory of Open Access Journals (Sweden)

    Safakish R

    2017-06-01

    Full Text Available Ramin Safakish Allevio Pain Management Clinic, Toronto, ON, Canada Abstract: Lower back pain (LBP is a global public health issue and is associated with substantial financial costs and loss of quality of life. Over the years, different literature has provided different statistics regarding the causes of the back pain. The following statistic is the closest estimation regarding our patient population. The sacroiliac (SI joint pain is responsible for LBP in 18%–30% of individuals with LBP. Quadrapolar™ radiofrequency ablation, which involves ablation of the nerves of the SI joint using heat, is a commonly used treatment for SI joint pain. However, the standard Quadrapolar radiofrequency procedure is not always effective at ablating all the sensory nerves that cause the pain in the SI joint. One of the major limitations of the standard Quadrapolar radiofrequency procedure is that it produces small lesions of ~4 mm in diameter. Smaller lesions increase the likelihood of failure to ablate all nociceptive input. In this study, we compare the standard Quadrapolar radiofrequency ablation technique to a modified Quadrapolar ablation technique that has produced improved patient outcomes in our clinic. The methodology of the two techniques are compared. In addition, we compare results from an experimental model comparing the lesion sizes produced by the two techniques. Taken together, the findings from this study suggest that the modified Quadrapolar technique provides longer lasting relief for the back pain that is caused by SI joint dysfunction. A randomized controlled clinical trial is the next step required to quantify the difference in symptom relief and quality of life produced by the two techniques. Keywords: lower back pain, radiofrequency ablation, sacroiliac joint, Quadrapolar radiofrequency ablation

  9. Improved convergence and stability properties in a three-dimensional higher-order ice sheet model

    Directory of Open Access Journals (Sweden)

    J. J. Fürst

    2011-12-01

    Full Text Available We present a finite difference implementation of a three-dimensional higher-order ice sheet model. In comparison to a conventional centred difference discretisation it enhances both numerical stability and convergence. In order to achieve these benefits the discretisation of the governing force balance equation makes extensive use of information on staggered grid points. Using the same iterative solver, a centred difference discretisation that operates exclusively on the regular grid serves as a reference. The reprise of the ISMIP-HOM experiments indicates that both discretisations are capable of reproducing the higher-order model inter-comparison results. This setup allows a direct comparison of the two numerical implementations also with respect to their convergence behaviour. First and foremost, the new finite difference scheme facilitates convergence by a factor of up to 7 and 2.6 in average. In addition to this decrease in computational costs, the accuracy for the resultant velocity field can be chosen higher in the novel finite difference implementation. Changing the discretisation also prevents build-up of local field irregularites that occasionally cause divergence of the solution for the reference discretisation.

    The improved behaviour makes the new discretisation more reliable for extensive application to real ice geometries. Higher accuracy and robust numerics are crucial in time dependent applications since numerical oscillations in the velocity field of subsequent time steps are attenuated and divergence of the solution is prevented.

  10. On the higher-spin spectrum in large N Chern-Simons vector models

    Science.gov (United States)

    Giombi, S.; Gurucharan, V.; Kirilin, V.; Prakash, S.; Skvortsov, E.

    2017-01-01

    Chern-Simons gauge theories coupled to massless fundamental scalars or fermions define interesting non-supersymmetric 3d CFTs that possess approximate higher-spin symmetries at large N . In this paper, we compute the scaling dimensions of the higher-spin operators in these models, to leading order in the 1 /N expansion and exactly in the 't Hooft coupling. We obtain these results in two independent ways: by using conformal symmetry and the classical equations of motion to fix the structure of the current non-conservation, and by a direct Feynman diagram calculation. The full dependence on the 't Hooft coupling can be restored by using results that follow from the weakly broken higher-spin symmetry. This analysis also allows us to obtain some explicit results for the non-conserved, parity-breaking structures that appear in planar three-point functions of the higher-spin operators. At large spin, we find that the anomalous dimensions grow logarithmically with the spin, in agreement with general expectations. This logarithmic behavior disappears in the strong coupling limit, where the anomalous dimensions turn into those of the critical O( N ) or Gross-Neveu models, in agreement with the conjectured 3d bosonization duality.

  11. Active Contour Model Coupling with Higher Order Diffusion for Medical Image Segmentation

    Directory of Open Access Journals (Sweden)

    Guodong Wang

    2014-01-01

    Full Text Available Active contour models are very popular in image segmentation. Different features such as mean gray and variance are selected for different purpose. But for image with intensity inhomogeneities, there are no features for segmentation using the active contour model. The images with intensity inhomogeneities often occurred in real world especially in medical images. To deal with the difficulties raised in image segmentation with intensity inhomogeneities, a new active contour model with higher-order diffusion method is proposed. With the addition of gradient and Laplace information, the active contour model can converge to the edge of the image even with the intensity inhomogeneities. Because of the introduction of Laplace information, the difference scheme becomes more difficult. To enhance the efficiency of the segmentation, the fast Split Bregman algorithm is designed for the segmentation implementation. The performance of our method is demonstrated through numerical experiments of some medical image segmentations with intensity inhomogeneities.

  12. Developing two non-parametric performance models for higher learning institutions

    Science.gov (United States)

    Kasim, Maznah Mat; Kashim, Rosmaini; Rahim, Rahela Abdul; Khan, Sahubar Ali Muhamed Nadhar

    2016-08-01

    Measuring the performance of higher learning Institutions (HLIs) is a must for these institutions to improve their excellence. This paper focuses on formation of two performance models: efficiency and effectiveness models by utilizing a non-parametric method, Data Envelopment Analysis (DEA). The proposed models are validated by measuring the performance of 16 public universities in Malaysia for year 2008. However, since data for one of the variables is unavailable, an estimate was used as a proxy to represent the real data. The results show that average efficiency and effectiveness scores were 0.817 and 0.900 respectively, while six universities were fully efficient and eight universities were fully effective. A total of six universities were both efficient and effective. It is suggested that the two proposed performance models would work as complementary methods to the existing performance appraisal method or as alternative methods in monitoring the performance of HLIs especially in Malaysia.

  13. Using Effective Models of Information and Communication Technology in Higher Education

    Directory of Open Access Journals (Sweden)

    Mansureh GHanbarpoor jooybari

    2013-08-01

    Full Text Available This study is going to represent some effective models of information and communication technology in higher education. The growth of educational content in the Internet industry and the increasing use of the Internet in the educational system have been quite rapid in the last few years. In the information transfer model, knowledge is passed from the experts (tutors to the learners (students by means of lectures and text books. The hope of increasing the educational impact by using impressive tools Based on ICT has serious disadvantage of increased cost. In this study we argue that new Low-cost Educational models based on constructivism can be used in parallel with traditional Learning introducing a blended (or enhanced learning approach. In such a blended environment, organizational, educational and technological issues need to be considered as a Whole. We introduce a light-weight blended educational model based on cooperation and experimentation.

  14. A HIGHER-ORDER NON-HYDROSTATIC MODEL FOR SIMULATING WAVE PROPAGATION OVER IRREGULAR BOTTOMS

    Institute of Scientific and Technical Information of China (English)

    AI Cong-fang; XING Yah; JIN Sheng

    2011-01-01

    A higher-order non-hydrostatic model is developed to simulate the wave propagation over irregular bottoms based on a vertical boundary-fitted coordinate system.In the model,an explicit projection method is adopted to solve the unsteady Euler equations.Advection terms are integrated explicitly with the MacCormack's scheme,with a second-order accuracy in both space and time.Two classical examples of surface wave propagation are used to demonstrate the capability of the model.It is found that the model with only two vertical layers could accurately simulate the motion of waves,including wave shoaling,nonlinearity,dispersion,refraction,and diffraction phenomena.

  15. Algebraic Specifications, Higher-order Types and Set-theoretic Models

    DEFF Research Database (Denmark)

    Kirchner, Hélène; Mosses, Peter David

    2001-01-01

    In most algebraic  specification frameworks, the type system is restricted to sorts, subsorts, and first-order function types. This is in marked contrast to the so-called model-oriented frameworks, which provide higer-order types, interpreted set-theoretically as Cartesian products, function spaces......, and power-sets. This paper presents a simple framework for algebraic specifications with higher-order types and set-theoretic models. It may be regarded as the basis for a Horn-clause approximation to the Z framework, and has the advantage of being amenable to prototyping and automated reasoning. Standard...

  16. Higher curvature effects in Arkani-Hamed-Dimopoulos-Dvali and Randall-Sundrum models

    Indian Academy of Sciences (India)

    T G Rizzo

    2007-11-01

    We explore the collider phenomenology of terascale extra-dimensional models with gravitational actions that contain higher curvature terms. In particular, we examine how the classic collider signatures of the models of Arkani-Hamed, Dimopoulos and Dvali (ADD) and of Randall and Sundrum (RS) are altered by these modifications to the usual Einstein-Hilbert (EH) action. Not only are the detailed signatures for gravitationally induced processes altered but new contributions are found to arise due to the existence of additional scalar Kaluza-Klein (KK) states in the spectrum.

  17. Phase structure of the $O(2)$ ghost model with higher-order gradient term

    CERN Document Server

    Péli, Z; Sailer, K

    2016-01-01

    The phase structure and the infrared behaviour of the Euclidean 3-dimensional $O(2)$ symmetric ghost scalar field model with higher-order derivative term has been investigated in Wegner and Houghton's renormalization group framework. The symmetric phase in which no ghost condensation occurs and the phase with restored symmetry but with a transient presence of a ghost condensate have been identified. Finiteness of the correlation length at the phase boundary hints to a phase transition of first order. The results are compared with those for the ordinary $O(2)$ symmetric scalar field model.

  18. Higher Derivative CP(N) Model and Quantization of the Induced Chern-Simons Term

    CERN Document Server

    Itoh, T; Itoh, Taichi; Oh, Phillial

    2001-01-01

    We consider higher derivative CP(N) model in 2+1 dimensions with the Wess-Zumino-Witten term and the topological current density squared term. We quantize the theory by using the auxiliary gauge field formulation in the path integral method and prove that the extended model remains renormalizable in the large N limit. We also find that the Maxwell-Chern-Simons theory is dynamically induced in the large N effective action and the coefficient of the Chern-Simons term must be quantized.

  19. A higher order lattice BGK model for simulating some nonlinear partial differential equations

    Institute of Scientific and Technical Information of China (English)

    LAI HuiLin; MA ChangFeng

    2009-01-01

    In this paper, we consider a one-dimensional nonlinear partial differential equation that has the form ut + αuux+βunux-γuxx+δuxxx= F(U). A higher order lattice Bhatnager-Gross-Krook (BGK) model with an amending-function is proposed. With the Chapman-Enskog expansion, different kinds of nonlinear partial differential equations are recovered correctly from the continuous Boltzmann equation. The numerical results show that this method is very effective.

  20. A higher order lattice BGK model for simulating some nonlinear partial differential equations

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    In this paper, we consider a one-dimensional nonlinear partial differential equation that has the form ut + αuux + βunux - γuxx + δuxxx = F(u). A higher order lattice Bhatnager-Gross-Krook (BGK) model with an amending-function is proposed. With the Chapman-Enskog expansion, different kinds of nonlinear partial differential equations are recovered correctly from the continuous Boltzmann equation. The numerical results show that this method is very effective.

  1. Extension of Lieb-Schupp theorem to Heisenberg models with higher-order interactions

    Science.gov (United States)

    Tanaka, Kengo

    2016-10-01

    We extend the Lieb-Schupp theorem to Heisenberg models with higher-order interactions on nonfrustrated or frustrated finite lattices. These lattices are constructed by even-numbered rings with or without crossing bonds and have reflection symmetry. The results show that the ground state has total spin zero in wide interaction parameter regions which are not covered by the results of Marshall-Lieb-Mattis-type arguments.

  2. On the decay of higher order derivatives of solutions to Ladyzhenskaya model for incompressible viscous flows

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    This article concerns large time behavior of Ladyzhenskaya model for incompressible viscous flows in R~3.Based on linear L~P-L~q estimates,the auxiliary decay properties of the solutions and generalized Gronwall type arguments,some optimal upper and lower bounds for the decay of higher order derivatives of solutions are derived without assuming any decay properties of solutions and using Fourier splitting technology.

  3. On the existence of anisotropic cosmological models in higher order theories of gravity

    OpenAIRE

    Middleton, Jonathan

    2010-01-01

    Abstract We investigate the behaviour on approach to the initial singularity in higher-order extensions of general relativity by finding exact cosmological solutions for a wide class of models in which the Lagrangian is allowed to depend nonlinearly upon the three possible linear and quadratic scalars built from the Riemann tensor ; R, R ab R ab and R abcd R abcd. We present new anisotropic vacuum solutions analagous to the Kasner solutions of general relativity and extend previous results...

  4. Incidence analysis of higher education financing system in Spain using a behavioural model.

    OpenAIRE

    Laura de Pablos Escobar; María Gil Izquierdo

    2008-01-01

    The aim of this paper is to analyse the distributive effects of some potential reforms in the Higher Education Financing System using a behavioural model, for the Spanish case in the new millennium. Specifically, improvements in income distribution due to some reforms in the educational policy are evaluated, based on international trends and “experts” recommendations. These measures refer to changes in quantity and coverage of grants, tuition fees and public subsidies per student in public un...

  5. Proofreading of DNA polymerase: a new kinetic model with higher-order terminal effects

    Science.gov (United States)

    Song, Yong-Shun; Shu, Yao-Gen; Zhou, Xin; Ou-Yang, Zhong-Can; Li, Ming

    2017-01-01

    The fidelity of DNA replication by DNA polymerase (DNAP) has long been an important issue in biology. While numerous experiments have revealed details of the molecular structure and working mechanism of DNAP which consists of both a polymerase site and an exonuclease (proofreading) site, there were quite a few theoretical studies on the fidelity issue. The first model which explicitly considered both sites was proposed in the 1970s and the basic idea was widely accepted by later models. However, all these models did not systematically investigate the dominant factor on DNAP fidelity, i.e. the higher-order terminal effects through which the polymerization pathway and the proofreading pathway coordinate to achieve high fidelity. In this paper, we propose a new and comprehensive kinetic model of DNAP based on some recent experimental observations, which includes previous models as special cases. We present a rigorous and unified treatment of the corresponding steady-state kinetic equations of any-order terminal effects, and derive analytical expressions for fidelity in terms of kinetic parameters under bio-relevant conditions. These expressions offer new insights on how the higher-order terminal effects contribute substantially to the fidelity in an order-by-order way, and also show that the polymerization-and-proofreading mechanism is dominated only by very few key parameters. We then apply these results to calculate the fidelity of some real DNAPs, which are in good agreements with previous intuitive estimates given by experimentalists.

  6. Marginal integrity of restorations produced with a model composite based on polyhedral oligomeric silsesquioxane (POSS

    Directory of Open Access Journals (Sweden)

    Luciano Ribeiro CORREA NETTO

    2015-10-01

    Full Text Available Marginal integrity is one of the most crucial aspects involved in the clinical longevity of resin composite restorations.Objective To analyze the marginal integrity of restorations produced with a model composite based on polyhedral oligomeric silsesquioxane (POSS.Material and Methods A base composite (B was produced with an organic matrix with UDMA/TEGDMA and 70 wt.% of barium borosilicate glass particles. To produce the model composite, 25 wt.% of UDMA were replaced by POSS (P25. The composites P90 and TPH3 (TP3 were used as positive and negative controls, respectively. Marginal integrity (%MI was analyzed in bonded class I cavities. The volumetric polymerization shrinkage (%VS and the polymerization shrinkage stress (Pss - MPa were also evaluated.Results The values for %MI were as follows: P90 (100% = TP3 (98.3% = B (96.9% > P25 (93.2%, (p<0.05. The %VS ranged from 1.4% (P90 to 4.9% (P25, while Pss ranged from 2.3 MPa (P90 to 3.9 MPa (B. For both properties, the composite P25 presented the worst results (4.9% and 3.6 MPa. Linear regression analysis showed a strong positive correlation between %VS and Pss (r=0.97, whereas the correlation between Pss and %MI was found to be moderate (r=0.76.Conclusions The addition of 25 wt.% of POSS in methacrylate organic matrix did not improve the marginal integrity of class I restorations. Filtek P90 showed lower polymerization shrinkage and shrinkage stress when compared to the experimental and commercial methacrylate composite.

  7. Functional copmponents produced by multi-jet modelling combined with electroforming and machining

    Directory of Open Access Journals (Sweden)

    Baier, Oliver

    2014-08-01

    Full Text Available In fuel cell technology, certain components are used that are responsible for guiding liquid media. When these components are produced by conventional manufacturing, there are often sealing issues, and trouble- and maintenance-free deployment cannot be ensured. Against this background, a new process combination has been developed in a joint project between the University of Duisburg-Essen, the Center for Fuel Cell Technology (ZBT, and the company Galvano-T electroplating forming GmbH. The approach is to combine multi-jet modelling (MJM, electroforming and milling in order to produce a defined external geometry. The wax models are generated on copper base plates and copper-coated to a desirable thickness. Following this, the undefined electroplated surfaces are machined to achieve the desired measurement, and the wax is melted out. This paper presents, first, how this process is technically feasible, then describes how the MJM on a 3-D Systems ThermoJet was adapted to stabilise the process.In the AiF-sponsored ZIM project, existing limits and possibilities are shown and different approaches of electroplating are investigated. This paper explores whether or not activation of the wax structure by a conductive initial layer is required. Using the described process chain, different parts were built: a heat exchanger, a vaporiser, and a reformer (in which pellets were integrated in an intermediate step. In addition, multiple-layer parts with different functions were built by repeating the process combination several times.

  8. Molecular Characterization of Growth Hormone-producing Tumors in the GC Rat Model of Acromegaly.

    Science.gov (United States)

    Martín-Rodríguez, Juan F; Muñoz-Bravo, Jose L; Ibañez-Costa, Alejandro; Fernandez-Maza, Laura; Balcerzyk, Marcin; Leal-Campanario, Rocío; Luque, Raúl M; Castaño, Justo P; Venegas-Moreno, Eva; Soto-Moreno, Alfonso; Leal-Cerro, Alfonso; Cano, David A

    2015-11-09

    Acromegaly is a disorder resulting from excessive production of growth hormone (GH) and consequent increase of insulin-like growth factor 1 (IGF-I), most frequently caused by pituitary adenomas. Elevated GH and IGF-I levels results in wide range of somatic, cardiovascular, endocrine, metabolic, and gastrointestinal morbidities. Subcutaneous implantation of the GH-secreting GC cell line in rats leads to the formation of tumors. GC tumor-bearing rats develop characteristics that resemble human acromegaly including gigantism and visceromegaly. However, GC tumors remain poorly characterized at a molecular level. In the present work, we report a detailed histological and molecular characterization of GC tumors using immunohistochemistry, molecular biology and imaging techniques. GC tumors display histopathological and molecular features of human GH-producing tumors, including hormone production, cell architecture, senescence activation and alterations in cell cycle gene expression. Furthermore, GC tumors cells displayed sensitivity to somatostatin analogues, drugs that are currently used in the treatment of human GH-producing adenomas, thus supporting the GC tumor model as a translational tool to evaluate therapeutic agents. The information obtained would help to maximize the usefulness of the GC rat model for research and preclinical studies in GH-secreting tumors.

  9. A Search for the Standard Model Higgs Boson Produced in Association with a $W$ Boson

    Energy Technology Data Exchange (ETDEWEB)

    Frank, Martin Johannes [Baylor Univ., Waco, TX (United States)

    2011-05-01

    We present a search for a standard model Higgs boson produced in association with a W boson using data collected with the CDF II detector from p$\\bar{p}$ collisions at √s = 1.96 TeV. The search is performed in the WH → ℓvb$\\bar{b}$ channel. The two quarks usually fragment into two jets, but sometimes a third jet can be produced via gluon radiation, so we have increased the standard two-jet sample by including events that contain three jets. We reconstruct the Higgs boson using two or three jets depending on the kinematics of the event. We find an improvement in our search sensitivity using the larger sample together with this multijet reconstruction technique. Our data show no evidence of a Higgs boson, so we set 95% confidence level upper limits on the WH production rate. We set limits between 3.36 and 28.7 times the standard model prediction for Higgs boson masses ranging from 100 to 150 GeV/c2.

  10. Simplification of the Flux Function for a Higher-order Gas-kinetic Evolution Model

    CERN Document Server

    Zhou, Guangzhao; Liu, Feng

    2016-01-01

    The higher-order gas-kinetic scheme for solving the Navier-Stokes equations has been studied in recent years. In addition to the use of higher-order reconstruction techniques, many terms are used in the Taylor expansion of the gas distribution functions. Therefore, a large number of coefficients need to be determined in the calculation of the time evolution of the gas distribution function at cell interfaces. As a consequence, the higher-order flux function takes much more computational time than that of a second-order gas-kinetic scheme. This paper aims to simplify the evolution model by two steps. Firstly, the coefficients related to the higher-order spatial and temporal derivatives of a distribution function are redefined to reduce the computational cost. Secondly, based on the physical analysis, some terms can be removed without loss of accuracy. Through the simplifications, the computational efficiency of the higher-order scheme is increased significantly. In addition, a self-adaptive numerical viscosity...

  11. Higher spin currents in the N =2 stringy coset minimal model

    Science.gov (United States)

    Ahn, Changhyun

    2016-12-01

    In the coset model based on (AN-1 (1 )⊕AN-1 (1 ),AN-1 (1 )) at level (N ,N ;2 N ), it is known that the N =2 superconformal algebra can be realized by the two kinds of adjoint fermions. Each Kac-Moody current of spin 1 is given by the product of fermions with structure constant (f symbols) as usual. One can construct the spin-1 current by combining the above two fermions with the structure constant and the spin-1 current by multiplying these two fermions with a completely symmetric S U (N ) invariant tensor of rank 3 (d symbols). The lowest higher spin-2 current with nonzero U (1 ) charge (corresponding to the zero mode eigenvalue of the spin-1 current of N =2 superconformal algebra) can be obtained from these four spin-1 currents in quadratic form. Similarly, the other type of lowest higher spin-2 current, whose U (1 ) charge is opposite to the above one, can be obtained also. Four higher spin-5/2 currents can be constructed from the operator product expansions (OPEs) between the spin-3/2 currents of N =2 superconformal algebra and the above two higher spin-2 currents. The two higher spin-3 currents can be determined by the OPEs between the above spin-3/2 currents and the higher spin-5/2 currents. Finally, the ten N =2 OPEs between the four N =2 higher spin multiplets (2 ,5/2 ,5/2 ,3 ) , (2 ,5/2 ,5/2 ,3 ) , (7/2 ,4 ,4 ,9/2 ) , and (7/2 ,4 ,4 ,9/2 ) are obtained explicitly for generic N .

  12. Yeast: the soul of beer's aroma--a review of flavour-active esters and higher alcohols produced by the brewing yeast.

    Science.gov (United States)

    Pires, Eduardo J; Teixeira, José A; Brányik, Tomás; Vicente, António A

    2014-03-01

    Among the most important factors influencing beer quality is the presence of well-adjusted amounts of higher alcohols and esters. Thus, a heavy body of literature focuses on these substances and on the parameters influencing their production by the brewing yeast. Additionally, the complex metabolic pathways involved in their synthesis require special attention. More than a century of data, mainly in genetic and proteomic fields, has built up enough information to describe in detail each step in the pathway for the synthesis of higher alcohols and their esters, but there is still place for more. Higher alcohols are formed either by anabolism or catabolism (Ehrlich pathway) of amino acids. Esters are formed by enzymatic condensation of organic acids and alcohols. The current paper reviews the up-to-date knowledge in the pathways involving the synthesis of higher alcohols and esters by brewing yeasts. Fermentation parameters affecting yeast response during biosynthesis of these aromatic substances are also fully reviewed.

  13. Confirmation and calibration of computer modeling of tsunamis produced by Augustine volcano, Alaska

    Science.gov (United States)

    Beget, James E.; Kowalik, Zygmunt

    2006-01-01

    Numerical modeling has been used to calculate the characteristics of a tsunami generated by a landslide into Cook Inlet from Augustine Volcano. The modeling predicts travel times of ca. 50-75 minutes to the nearest populated areas, and indicates that significant wave amplification occurs near Mt. Iliamna on the western side of Cook Inlet, and near the Nanwelak and the Homer-Anchor Point areas on the east side of Cook Inlet. Augustine volcano last produced a tsunami during an eruption in 1883, and field evidence of the extent and height of the 1883 tsunamis can be used to test and constrain the results of the computer modeling. Tsunami deposits on Augustine Island indicate waves near the landslide source were more than 19 m high, while 1883 tsunami deposits in distal sites record waves 6-8 m high. Paleotsunami deposits were found at sites along the coast near Mt. Iliamna, Nanwelak, and Homer, consistent with numerical modeling indicating significant tsunami wave amplification occurs in these areas. 

  14. Brain mechanisms for predictive control by switching internal models: implications for higher-order cognitive functions.

    Science.gov (United States)

    Imamizu, Hiroshi; Kawato, Mitsuo

    2009-07-01

    Humans can guide their actions toward the realization of their intentions. Flexible, rapid and precise realization of intentions and goals relies on the brain learning to control its actions on external objects and to predict the consequences of this control. Neural mechanisms that mimic the input-output properties of our own body and other objects can be used to support prediction and control, and such mechanisms are called internal models. We first summarize functional neuroimaging, behavioral and computational studies of the brain mechanisms related to acquisition, modular organization, and the predictive switching of internal models mainly for tool use. These mechanisms support predictive control and flexible switching of intentional actions. We then review recent studies demonstrating that internal models are crucial for the execution of not only immediate actions but also higher-order cognitive functions, including optimization of behaviors toward long-term goals, social interactions based on prediction of others' actions and mental states, and language processing. These studies suggest that a concept of internal models can consistently explain the neural mechanisms and computational principles needed for fundamental sensorimotor functions as well as higher-order cognitive functions.

  15. Higher spin currents in the enhanced N=3 Kazama-Suzuki model

    Science.gov (United States)

    Ahn, Changhyun; Kim, Hyunsu

    2016-12-01

    The N=3 Kazama-Suzuki model at the `critical' level has been found by Creutzig, Hikida and Ronne. We construct the lowest higher spin currents of spins (3/2,2,2,2,5/2,5/2,5/2,3) in terms of various fermions. In order to obtain the operator product expansions (OPEs) between these higher spin currents, we describe three N=2 OPEs between the two N=2 higher spin currents denoted by (3/2,2,2,5/2) and (2,5/2,5/2,3) (corresponding 36 OPEs in the component approach). Using the various Jacobi identities, the coefficient functions appearing on the right hand side of these N=2 OPEs are deter-mined in terms of central charge completely. Then we describe them as one single N=3 OPE in the N=3 superspace. The right hand side of this N=3 OPE contains the SO(3)-singlet N=3 higher spin multiplet of spins (2,5/2,5/2,5/2,3,3,3,7/2) , the SO(3)-singlet N=3 higher spin multiplet of spins (5/2,3,3,3,7/2,7/2,7/2,4) , and the SO(3)-triplet N=3 higher spin multiplets where each multiplet has the spins (3,7/2,7/2,7/2,4,4,4,9/2) , in addition to N=3 superconformal family of the identity operator. Finally, by factoring out the spin-1/2 current of N=3 linear superconformal algebra generated by eight currents of spins (1/2,1,1,1,3/2,3/2,3/2,2) , we obtain the extension of so-called SO (3) nonlinear Knizhnik Bershadsky algebra.

  16. Olfactory Impact of Higher Alcohols on Red Wine Fruity Ester Aroma Expression in Model Solution.

    Science.gov (United States)

    Cameleyre, Margaux; Lytra, Georgia; Tempere, Sophie; Barbe, Jean-Christophe

    2015-11-11

    This study focused on the impact of five higher alcohols on the perception of fruity aroma in red wines. Various aromatic reconstitutions were prepared, consisting of 13 ethyl esters and acetates and 5 higher alcohols, all at the average concentrations found in red wine. These aromatic reconstitutions were prepared in several matrices. Sensory analysis revealed the interesting behavior of certain compounds among the five higher alcohols following their individual addition or omission. The "olfactory threshold" of the fruity pool was evaluated in several matrices: dilute alcohol solution, dilute alcohol solution containing 3-methylbutan-1-ol or butan-1-ol individually, and dilute alcohol solution containing the mixture of five higher alcohols, blended together at various concentrations. The presence of 3-methylbutan-1-ol or butan-1-ol alone led to a significant decrease in the "olfactory threshold" of the fruity reconstitution, whereas the mixture of alcohols raised the olfactory threshold. Sensory profiles highlighted changes in the perception of fruity nuances in the presence of the mixture of higher alcohols, with specific perceptive interactions, including a relevant masking effect on fresh- and jammy-fruit notes of the fruity mixture in both dilute alcohol solution and dearomatized red wine matrices. When either 3-methylbutan-1-ol or butan-1-ol was added to the fruity reconstitution in dilute alcohol solution, an enhancement of butyric notes was reported with 3-methylbutan-1-ol and fresh- and jammy-fruit with butan-1-ol. This study, the first to focus on the impact of higher alcohols on fruity aromatic expression, revealed that these compounds participate, both quantitatively and qualitatively, in masking fruity aroma perception in a model fruity wine mixture.

  17. Numerical modeling of the inception, morphology and radio signals of sprites produced by lightning discharges with positive and negative polarity

    Science.gov (United States)

    Qin, Jianqi

    conditions (i.e., the ambient electron and ion density) on the threshold charge moment changes required to produce column sprites and carrot sprites. To understand the lightning polarity asymmetry in producing sprites, we investigate possible differences between the requirements for the initiation of positive and negative sprites. A parametric study shows that positive sprites require an ambient electric field with smaller magnitude and shorter persistence when compared to those required for the initiation of negative sprites. Consequently, the initiation of positive sprites requires a smaller threshold charge moment change than that of negative sprites (320 C km and 500 C km, respectively, under typical nighttime conditions). This difference between the initiation thresholds represents one of the key factors accounting for the polarity asymmetry of sprites. Other factors, including the charge moment contrast of +CGs and -CGs, and the differences originating from physical properties of streamers and observability of positive and negative sprites are also discussed. This dissertation work presents the first theoretical estimates of the electromagnetic radiation produced by individual sprite streamers using simulation results from plasma fluid modeling. It is demonstrated that the spectral content of the sprite radiation is highly dependent on the air density and the ambient electric field, i.e., sprite streamers propagating at lower altitudes with higher air density or propagating in a higher electric field produce a higher frequency radiation. Most interestingly, we quantitatively demonstrate that sprite streamers at low altitudes (˜40 km) can produce VLF and LF radiation, that needs to be confirmed by future radio observations. Finally, this dissertation work presents research efforts that are devoted to a direct comparison of morphological features predicted by the streamer model with those appearing in video observations in order to derive the mechanism of column and

  18. Applicability of the Maturity Model for IT Service Outsourcing in Higher Education Institutions

    Directory of Open Access Journals (Sweden)

    Victoriano Valencia García

    2014-08-01

    Full Text Available Outsourcing is a strategic option which complements IT services provided internally in organizations. This study proposes the applicability of a new holistic maturity model based on standards ISO/IEC 20000 and ISO/IEC 38500, and the frameworks and best practices of ITIL and COBIT, with a specific focus on IT outsourcing. This model allows independent validation and practical application in the field of higher education. In addition, this study allows to achieve an effective transition to a model of good governance and management of outsourced IT services which, aligned with the core business of universities, affect the effectiveness and efficiency of its management, optimizes its value and minimizes risks.

  19. Higher order effective interactions and effective bosonized model for 2-N particle states

    Directory of Open Access Journals (Sweden)

    Braghin Fabio L.

    2016-01-01

    Full Text Available In this work, an effective fermion model with particular higher order interactions given by: III=∑nNg2n(ψ¯aψa2n${I_{II}} = \\mathop \\sum \\limits_n^N g{2^n}{({\\bar \\psi _a}{\\psi _a}^{{2^n}}}$, for finite N, is investigated by means of the auxiliary field method by taking into account 2n-particle states as proposed in Ref. [1]. The bosonized model was found to exhibit an approximate symmetry when expanded for weak field fluctuations around the mean field solutions. In the present work, the role of the mean field solutions for the corresponding auxiliary fields is investigated. With the integration of fermions, the resulting determinant is expanded in a polynomial boson model in the weak field approximation and the approximate symmetry found for this series does not appear if the boson mean fields are considered to be zero.

  20. The Magnetic Model of the LHC during Commissioning to higher Beam Intensities in 2010-2011

    CERN Document Server

    Deniau, L; Fiscarelli, L; Giovannozzi, M; Hagen, P; Lamont, M; Montenero, G; Steinhagen, R; Strzelczyk, M; Todesco, E; Tomas, R; Venturini Delsolaro, W; Wenninger, J

    2011-01-01

    The Field Description of the Large Hadron Collider (FiDeL) model is a set of semi-empirical equations linking the magnets behaviours established from magnetic measurements to the magnetic properties of the machine observed through beam measurements. The FiDeL model includes the parameterization of static and dynamic (time dependent) components. In the present paper, we outline the relationship between the beam observables (orbit, tune, chromaticity) and the model components during the commissioning to higher beam intensities in 2010-2011, with energy of 3.5 TeV per beam. The main relevant issues are (i) the operation at 10 A/s ramp rate and their influence on chromatic correction, (ii) the beta beating and its relation to the quadrupoles transfer functions and (iii) the origin of the observed tune decay at injection.

  1. Model of Developing Information Literacy for Iranian Ministry of Higher Education (MSRT

    Directory of Open Access Journals (Sweden)

    Ali Hossein Ghasemi

    2012-03-01

    Full Text Available This paper presented a model on developing information literacy for Iranian Ministry of Science, Research and Technology. This model was based on three sides: formulating rules and regulations, content production, and communication among the activists. In each of these sides, while referring to noting-worthy points, the top possible actions were mentioned. It was expected that by achieving information literacy skills that entails equipping the learners with critical thinking skills, much of the national objectives aimed in cultural, social, economic and scientific fields areas will be attained; all since that the first step in accessing knowledge (the main characteristic of which is being localized consists of the ability to recognize the problem, to determine the information need clearly, and to exploit the existing information in producing new information and knowledge.

  2. Investigation of Higher Brain Functions in Music Composition Using Models of the Cortex Based on Physical System Analogies.

    Science.gov (United States)

    Leng, Xiaodan

    The trion model was developed using the Mountcastle organizational principle for the column as the basic neuronal network in the cortex and the physical system analogy of Fisher's ANNNI spin model. An essential feature is that it is highly structured in time and in spatial connections. Simulations of a network of trions have shown that large numbers of quasi-stable, periodic spatial-temporal firing patterns can be excited. Characteristics of these patterns include the quality of being readily enhanced by only a small change in connection strengths, and that the patterns evolve in certain natural sequences from one to another. With only somewhat different parameters than used for studying memory and pattern recognition, much more flowing and intriguing patterns emerged from the simulations. The results were striking when these probabilistic evolutions were mapped onto pitches and instruments to produce music: For example different simple mappings of the same evolution give music having the "flavor" of a minuet, a waltz, folk music, or styles of specific periods. A theme can be learned so that evolutions have this theme and its variations reoccurring more often. That the trion model is a viable model for the coding of musical structure in human composition and perception is suggested. It is further proposed that model is relevant for examining creativity in the higher cognitive functions of mathematics and chess, which are similar to music. An even higher level of cortical organization was modeled by coupling together several trion networks. Further, one of the crucial features of higher brain function, especially in music composition or appreciation, is the role of emotion and mood as controlled by the many neuromodulators or neuropeptides. The MILA model whose underlying basis is zero-level representation of Kac-Moody algebra is used to modulate periodically the firing threshold of each network. Our preliminary results show that the introduction of "neuromodulation

  3. Compositional modeling of three-phase flow with gravity using higher-order finite element methods

    Science.gov (United States)

    Moortgat, Joachim; Sun, Shuyu; Firoozabadi, Abbas

    2011-05-01

    A wide range of applications in subsurface flow involve water, a nonaqueous phase liquid (NAPL) or oil, and a gas phase, such as air or CO2. The numerical simulation of such processes is computationally challenging and requires accurate compositional modeling of three-phase flow in porous media. In this work, we simulate for the first time three-phase compositional flow using higher-order finite element methods. Gravity poses complications in modeling multiphase processes because it drives countercurrent flow among phases. To resolve this issue, we propose a new method for the upwinding of three-phase mobilities. Numerical examples, related to enhanced oil recovery and carbon sequestration, are presented to illustrate the capabilities of the proposed algorithm. We pay special attention to challenges associated with gravitational instabilities and take into account compressibility and various phase behavior effects, including swelling, viscosity changes, and vaporization. We find that the proposed higher-order method can capture sharp solution discontinuities, yielding accurate predictions of phase boundaries arising in computational three-phase flow. This work sets the stage for a broad extension of the higher-order methods for numerical simulation of three-phase flow for complex geometries and processes.

  4. Compositional modeling of three-phase flow with gravity using higher-order finite element methods

    KAUST Repository

    Moortgat, Joachim

    2011-05-11

    A wide range of applications in subsurface flow involve water, a nonaqueous phase liquid (NAPL) or oil, and a gas phase, such as air or CO2. The numerical simulation of such processes is computationally challenging and requires accurate compositional modeling of three-phase flow in porous media. In this work, we simulate for the first time three-phase compositional flow using higher-order finite element methods. Gravity poses complications in modeling multiphase processes because it drives countercurrent flow among phases. To resolve this issue, we propose a new method for the upwinding of three-phase mobilities. Numerical examples, related to enhanced oil recovery and carbon sequestration, are presented to illustrate the capabilities of the proposed algorithm. We pay special attention to challenges associated with gravitational instabilities and take into account compressibility and various phase behavior effects, including swelling, viscosity changes, and vaporization. We find that the proposed higher-order method can capture sharp solution discontinuities, yielding accurate predictions of phase boundaries arising in computational three-phase flow. This work sets the stage for a broad extension of the higher-order methods for numerical simulation of three-phase flow for complex geometries and processes.

  5. A semi-empirical model for mesospheric and stratospheric NOy produced by energetic particle precipitation

    Science.gov (United States)

    Funke, Bernd; López-Puertas, Manuel; Stiller, Gabriele P.; Versick, Stefan; von Clarmann, Thomas

    2016-07-01

    The MIPAS Fourier transform spectrometer on board Envisat has measured global distributions of the six principal reactive nitrogen (NOy) compounds (HNO3, NO2, NO, N2O5, ClONO2, and HNO4) during 2002-2012. These observations were used previously to detect regular polar winter descent of reactive nitrogen produced by energetic particle precipitation (EPP) down to the lower stratosphere, often called the EPP indirect effect. It has further been shown that the observed fraction of NOy produced by EPP (EPP-NOy) has a nearly linear relationship with the geomagnetic Ap index when taking into account the time lag introduced by transport. Here we exploit these results in a semi-empirical model for computation of EPP-modulated NOy densities and wintertime downward fluxes through stratospheric and mesospheric pressure levels. Since the Ap dependence of EPP-NOy is distorted during episodes of strong descent in Arctic winters associated with elevated stratopause events, a specific parameterization has been developed for these episodes. This model accurately reproduces the observations from MIPAS and is also consistent with estimates from other satellite instruments. Since stratospheric EPP-NOy depositions lead to changes in stratospheric ozone with possible implications for climate, the model presented here can be utilized in climate simulations without the need to incorporate many thermospheric and upper mesospheric processes. By employing historical geomagnetic indices, the model also allows for reconstruction of the EPP indirect effect since 1850. We found secular variations of solar cycle-averaged stratospheric EPP-NOy depositions on the order of 1 GM. In particular, we model a reduction of the EPP-NOy deposition rate during the last 3 decades, related to the coincident decline of geomagnetic activity that corresponds to 1.8 % of the NOy production rate by N2O oxidation. As the decline of the geomagnetic activity level is expected to continue in the coming decades, this is

  6. Assessment of the Quality of Digital Terrain Model Produced from Unmanned Aerial System Imagery

    Science.gov (United States)

    Kosmatin Fras, M.; Kerin, A.; Mesarič, M.; Peterman, V.; Grigillo, D.

    2016-06-01

    Production of digital terrain model (DTM) is one of the most usual tasks when processing photogrammetric point cloud generated from Unmanned Aerial System (UAS) imagery. The quality of the DTM produced in this way depends on different factors: the quality of imagery, image orientation and camera calibration, point cloud filtering, interpolation methods etc. However, the assessment of the real quality of DTM is very important for its further use and applications. In this paper we first describe the main steps of UAS imagery acquisition and processing based on practical test field survey and data. The main focus of this paper is to present the approach to DTM quality assessment and to give a practical example on the test field data. For data processing and DTM quality assessment presented in this paper mainly the in-house developed computer programs have been used. The quality of DTM comprises its accuracy, density, and completeness. Different accuracy measures like RMSE, median, normalized median absolute deviation and their confidence interval, quantiles are computed. The completeness of the DTM is very often overlooked quality parameter, but when DTM is produced from the point cloud this should not be neglected as some areas might be very sparsely covered by points. The original density is presented with density plot or map. The completeness is presented by the map of point density and the map of distances between grid points and terrain points. The results in the test area show great potential of the DTM produced from UAS imagery, in the sense of detailed representation of the terrain as well as good height accuracy.

  7. From research excellence to brand relevance: A model for higher education reputation building

    Directory of Open Access Journals (Sweden)

    Nina Overton-de Klerk

    2016-05-01

    Full Text Available In this article we propose a novel approach to reputation development at higher education institutions. Global reputation development at higher education institutions is largely driven by research excellence, is predominantly measured by research output, and is predominantly reflected in hierarchical university rankings. The ranking becomes equated with brand equity. We argue that the current approach to reputation development in higher education institutions is modernist and linear. This is strangely out-of-kilter with the complexities of a transforming society in flux, the demands of a diversity of stakeholders, and the drive towards transdisciplinarity, laterality, reflexivity and relevance in science. Good research clearly remains an important ingredient of a university's brand value. However, a case can be made for brand relevance, co-created in collaboration with stakeholders, as an alternative and non-linear way of differentiation. This approach is appropriate in light of challenges in strategic science globally as well as trends and shifts in the emerging paradigm of strategic communication. In applying strategic communication principles to current trends and issues in strategic science and the communication thereof, an alternative model for strategic reputation building at higher education institutions is developed.

  8. On the Higher-Spin Spectrum in Large N Chern-Simons Vector Models

    CERN Document Server

    Giombi, S; Kirilin, V; Prakash, S; Skvortsov, E

    2016-01-01

    Chern-Simons gauge theories coupled to massless fundamental scalars or fermions define interesting non-supersymmetric 3d CFTs that possess approximate higher-spin symmetries at large N. In this paper, we compute the scaling dimensions of the higher-spin operators in these models, to leading order in the 1/N expansion and exactly in the 't Hooft coupling. We obtain these results in two independent ways: by using conformal symmetry and the classical equations of motion to fix the structure of the current non-conservation, and by a direct Feynman diagram calculation. The full dependence on the 't Hooft coupling can be restored by using results that follow from the weakly broken higher-spin symmetry. This analysis also allows us to obtain some explicit results for the non-conserved, parity-breaking structures that appear in planar three-point functions of the higher-spin operators. At large spin, we find that the anomalous dimensions grow logarithmically with the spin, in agreement with general expectations. This...

  9. Mechanistic modeling of biocorrosion caused by biofilms of sulfate reducing bacteria and acid producing bacteria.

    Science.gov (United States)

    Xu, Dake; Li, Yingchao; Gu, Tingyue

    2016-08-01

    Biocorrosion is also known as microbiologically influenced corrosion (MIC). Most anaerobic MIC cases can be classified into two major types. Type I MIC involves non-oxygen oxidants such as sulfate and nitrate that require biocatalysis for their reduction in the cytoplasm of microbes such as sulfate reducing bacteria (SRB) and nitrate reducing bacteria (NRB). This means that the extracellular electrons from the oxidation of metal such as iron must be transported across cell walls into the cytoplasm. Type II MIC involves oxidants such as protons that are secreted by microbes such as acid producing bacteria (APB). The biofilms in this case supply the locally high concentrations of oxidants that are corrosive without biocatalysis. This work describes a mechanistic model that is based on the biocatalytic cathodic sulfate reduction (BCSR) theory. The model utilizes charge transfer and mass transfer concepts to describe the SRB biocorrosion process. The model also includes a mechanism to describe APB attack based on the local acidic pH at a pit bottom. A pitting prediction software package has been created based on the mechanisms. It predicts long-term pitting rates and worst-case scenarios after calibration using SRB short-term pit depth data. Various parameters can be investigated through computer simulation.

  10. Synthesis and Modeling of Temperature Distribution For Nanoparticles Produced Using Nd:YAG Lasers

    Directory of Open Access Journals (Sweden)

    Mu’ataz S. Hassan

    2016-01-01

    Full Text Available Nanosecond pulses of Nd:YAG laser were employed to produce silver and silicon nanoparticles by laser ablation process in liquid. Two Nd:YAG laser systems of 6 and 10 nanoseconds pulse duration with variable laser energy in the range 700–760 mJ were employed. Morphological investigation using AFM and TEM reveals the formation of silver and silicon nanoparticles with uniform size distribution. It is found that mean nanoparticles sizes of 50 and 70 nm for silver and silicon, respectively, are produced under similar laser parameters. Moreover, theoretical model was used to estimate the temperature distributions for both silver and silicon nanoparticles. It is also found that the maximum temperature of about 50 k K° and 70 k K° for silver and silicon nanoparticles, respectively, is generated when Nd:YAG of 10 ns is used to prepare nanoparticles. Zeta potential measurements reveal that silver nanoparticles are more stable than those of silicon prepared by similar conditions.

  11. Analytic modeling of instabilities driven by higher-order modes in the HLS Ⅱ RF system with a higher-harmonic cavity

    Institute of Scientific and Technical Information of China (English)

    ZHAO Yu-Ning; LI Wei-Min; WU Cong-Feng; WANG Lin

    2013-01-01

    The utility of a passive fourth-harmonic cavity plays a key role in suppressing longitudinal beam instabilities in the electron storage ring and lengthens the bunch by a factor of 2.6 for the phase Ⅱ project of the Hefei Light Source (HLS Ⅱ).Meanwhile,instabilities driven by higher-order modes (HOM) may limit the performance of the higher-harmonic cavity.In this paper,the parasitic coupled-bunch instability,which is driven by narrow band parasitic modes,and the microwave instability,which is driven by broadband HOM,are both modeled analytically.The analytic modeling results are in good agreement with those of our previous simulation study and indicate that the passive fourth-harmonic cavity suppresses parasitic coupled-bunch instabilities and microwave instability.The modeling suggests that a fourth-harmonic cavity may be successfully used at the HLS Ⅱ.

  12. Analytic modeling of instabilities driven by higher-order modes in HLS II RF system with a higher-harmonic cavity

    CERN Document Server

    Zhao, Yuning; Wu, Congfeng; Wang, Lin

    2013-01-01

    The utility of a passive fourth-harmonic cavity plays key role in suppressing longitudinal beam instabilities in the electron storage ring and lengthens the bunch by a factor of 2.6 for the phase II project of Hefei Light Source(HLS II). Meanwhile, instabilities driven by higher-order modes(HOM) may limit the performance of the higher-harmonic cavity. In this paper, the parasitic coupled-bunch instability which is driven by narrow band parasitic modes and the microwave instability which is driven by broadband HOM are both modeled analytically. The analytic modeling results are in good agreement with that of our previous simulation study and indicate that the passive fourth-harmonic cavity suppresses parasitic coupled-bunch instabilities and the microwave instability. The modeling suggests that a fourth-harmonic cavity may be successfully used at HLS II.

  13. Sectoral Structure Change Modeling of European Oil and Gas Producing Country’S Economy

    Directory of Open Access Journals (Sweden)

    Perepelkin Viacheslav Alexandrovich

    2015-12-01

    Full Text Available In this paper, we consider identifying features of sectoral structuring within the national economy that has definite foreign trade product specialization. Examination of the sector-specific division methodology enabled identification of its strong association with certain sector dominance in the economy. It is against this background that we offer an explanation for the delay in transferring from the post-Soviet to the applicable international classification of economic structure elements in Russia and Belarus. We perform analysis of the three-component P-S-T model (primary, secondary, tertiary sector using statistical and econometric methods and define properties of the sectoral shares dynamics in national economies of oil and gas producing countries. Analysis of the Russian and Norwegian economies’ intersectoral changes suggests that it is necessary for the government to develop and implement selective structural policy to overcome the existing structural disproportions.

  14. Higher dimensional charged shear-free relativistic models with heat flux

    CERN Document Server

    Nyonyi, Y; Govinder, K S

    2014-01-01

    We analyse shear-free spherically symmetric relativistic models of gravitating fluids with heat flow and electric charge defined on higher dimensional manifolds. The solution to the Einstein-Maxwell system is governed by the pressure isotropy condition which depends on the spacetime dimension. We study this highly nonlinear partial differential equation using Lie's group theoretic approach. The Lie symmetry generators that leave the equation invariant are determined. We provide exact solutions to the gravitational potentials using the first symmetry admitted by the equation. Our new exact solutions contain the earlier results for the four-dimensional case. Using the other Lie generators, we are able to provide solutions to the gravitational potentials or reduce the order of the master equation to a first order nonlinear differential equation. We derive the temperature transport equation in higher dimensions and find expressions for the causal and Eckart temperatures showing their explicit dependance on the di...

  15. The comet assay in higher terrestrial plant model: Review and evolutionary trends.

    Science.gov (United States)

    Lanier, Caroline; Manier, Nicolas; Cuny, Damien; Deram, Annabelle

    2015-12-01

    The comet assay is a sensitive technique for the measurement of DNA damage in individual cells. Although it has been primarily applied to animal cells, its adaptation to higher plant tissues significantly extends the utility of plants for environmental genotoxicity research. The present review focuses on 101 key publications and discusses protocols and evolutionary trends specific to higher plants. General consensus validates the use of the percentage of DNA found in the tail, the alkaline version of the test and root study. The comet protocol has proved its effectiveness and its adaptability for cultivated plant models. Its transposition in wild plants thus appears as a logical evolution. However, certain aspects of the protocol can be improved, namely through the systematic use of positive controls and increasing the number of nuclei read. These optimizations will permit the increase in the performance of this test, namely when interpreting mechanistic and physiological phenomena.

  16. ACADEMIC DISHONESTY IN DISTANCE HIGHER EDUCATION: Challenges and Models for Moral Education in the Digital Era

    Directory of Open Access Journals (Sweden)

    Mohammad Imam FARISI

    2013-10-01

    Full Text Available Today, in the era of open access to digital-based information and communication, one of the biggest challenges in higher education to realize moral education and to build academic culture and integrity is the emergence of academic dishonesty behaviors among academic members. The paper describes academic dishonesty behaviors in Distance Higher Education (DHE institutions within the context of moral education in the digital era. The paper reviews the results of the research on academic dishonesty behaviors and practices in DHE institutions worldwide; factors which have a very significant role for the emergence of academic dishonesty behaviors and practices. It is also discusses an integrated model of moral education as interdisciplinary strategy in combating academic dishonesty and in promoting academic culture and integrity in DHE.

  17. Practice Models and Public Policies in the Management and Governance of Higher Education

    Directory of Open Access Journals (Sweden)

    Constantin BRĂTIANU

    2010-02-01

    Full Text Available Since the end of the last century, there  have been lots of analyses on the evolution of  various basic types of structures of authority and  academic governance patterns, public policies and  practice models, all together in search of the most  effective formula for adapting the higher education  institutions to the new educational requirements  and trends of the global market, characterized by  increasing competition. In this context, our paper  provides a succinct analysis of the worldwide trends  in the governance and management of higher  education with an emphasis on Europe and on  the evolution of the Romanian universities, in the  context of the public policies promoted during time.  

  18. Knowledge Management in Higher Education : Applicability of LKMC Model in Saudi Universities

    Directory of Open Access Journals (Sweden)

    Farzana Shafique

    2015-01-01

    Full Text Available This paper stresses on the need of using Knowledge Management (KM in the higher education institutions of Saudi Arabia. The paper is based on the literature review and personal experience of the author in the education sector. The paper aims at highlighting the importance of KM for the educational institutions particularly for developing countries. It also revi ews the readiness of Saudi Arabia for KM application by illustrating different development i nitiatives taken by the Saudi government in different sectors. However, the literature also ide ntifies many barriers on the way. Keeping the importance of KM for the higher educati on institutions in view, this paper proposes to adopt the model of Library Knowledge Management Center (LKMC with needed modifications for Universities of Saudi Arabia. Thi s LKMC model was proposed by Parker, Nitse, and Flowers (2005 for the small business co rporate for providing the Knowledge Management (KM and Competitive Intelligence (CI s ervices. The paper discusses different components of the LKMC model and their relevance to the education sector.

  19. First and Higher Order Effects on Zero Order Radiative Transfer Model

    Science.gov (United States)

    Neelam, M.; Mohanty, B.

    2014-12-01

    Microwave radiative transfer model are valuable tool in understanding the complex land surface interactions. Past literature has largely focused on local sensitivity analysis for factor priotization and ignoring the interactions between the variables and uncertainties around them. Since land surface interactions are largely nonlinear, there always exist uncertainties, heterogeneities and interactions thus it is important to quantify them to draw accurate conclusions. In this effort, we used global sensitivity analysis to address the issues of variable uncertainty, higher order interactions, factor priotization and factor fixing for zero-order radiative transfer (ZRT) model. With the to-be-launched Soil Moisture Active Passive (SMAP) mission of NASA, it is very important to have a complete understanding of ZRT for soil moisture retrieval to direct future research and cal/val field campaigns. This is a first attempt to use GSA technique to quantify first order and higher order effects on brightness temperature from ZRT model. Our analyses reflect conditions observed during the growing agricultural season for corn and soybeans in two different regions in - Iowa, U.S.A and Winnipeg, Canada. We found that for corn fields in Iowa, there exist significant second order interactions between soil moisture, surface roughness parameters (RMS height and correlation length) and vegetation parameters (vegetation water content, structure and scattering albedo), whereas in Winnipeg, second order interactions are mainly due to soil moisture and vegetation parameters. But for soybean fields in both Iowa and Winnipeg, we found significant interactions only to exist between soil moisture and surface roughness parameters.

  20. Modeling change in learning strategies throughout higher education: a multi-indicator latent growth perspective.

    Directory of Open Access Journals (Sweden)

    Liesje Coertjens

    Full Text Available The change in learning strategies during higher education is an important topic of research in the Student Approaches to Learning field. Although the studies on this topic are increasingly longitudinal, analyses have continued to rely primarily on traditional statistical methods. The present research is innovative in the way it uses a multi-indicator latent growth analysis in order to more accurately estimate the general and differential development in learning strategy scales. Moreover, the predictive strength of the latent growth models are estimated. The sample consists of one cohort of Flemish University College students, 245 of whom participated in the three measurement waves by filling out the processing and regulation strategies scales of the Inventory of Learning Styles--Short Versions. Independent-samples t-tests revealed that the longitudinal group is a non-random subset of students starting University College. For each scale, a multi-indicator latent growth model is estimated using Mplus 6.1. Results suggest that, on average, during higher education, students persisting in their studies in a non-delayed manner seem to shift towards high-quality learning and away from undirected and surface-oriented learning. Moreover, students from the longitudinal group are found to vary in their initial levels, while, unexpectedly, not in their change over time. Although the growth models fit the data well, significant residual variances in the latent factors remain.

  1. On the Entropy Based Associative Memory Model with Higher-Order Correlations

    Directory of Open Access Journals (Sweden)

    Masahiro Nakagawa

    2010-01-01

    Full Text Available In this paper, an entropy based associative memory model will be proposed and applied to memory retrievals with an orthogonal learning model so as to compare with the conventional model based on the quadratic Lyapunov functional to be minimized during the retrieval process. In the present approach, the updating dynamics will be constructed on the basis of the entropy minimization strategy which may be reduced asymptotically to the above-mentioned conventional dynamics as a special case ignoring the higher-order correlations. According to the introduction of the entropy functional, one may involve higer-order correlation effects between neurons in a self-contained manner without any heuristic coupling coefficients as in the conventional manner. In fact we shall show such higher order coupling tensors are to be uniquely determined in the framework of the entropy based approach. From numerical results, it will be found that the presently proposed novel approach realizes much larger memory capacity than that of the quadratic Lyapunov functional approach, e.g., associatron.

  2. Modeling change in learning strategies throughout higher education: a multi-indicator latent growth perspective.

    Science.gov (United States)

    Coertjens, Liesje; Donche, Vincent; De Maeyer, Sven; Vanthournout, Gert; Van Petegem, Peter

    2013-01-01

    The change in learning strategies during higher education is an important topic of research in the Student Approaches to Learning field. Although the studies on this topic are increasingly longitudinal, analyses have continued to rely primarily on traditional statistical methods. The present research is innovative in the way it uses a multi-indicator latent growth analysis in order to more accurately estimate the general and differential development in learning strategy scales. Moreover, the predictive strength of the latent growth models are estimated. The sample consists of one cohort of Flemish University College students, 245 of whom participated in the three measurement waves by filling out the processing and regulation strategies scales of the Inventory of Learning Styles--Short Versions. Independent-samples t-tests revealed that the longitudinal group is a non-random subset of students starting University College. For each scale, a multi-indicator latent growth model is estimated using Mplus 6.1. Results suggest that, on average, during higher education, students persisting in their studies in a non-delayed manner seem to shift towards high-quality learning and away from undirected and surface-oriented learning. Moreover, students from the longitudinal group are found to vary in their initial levels, while, unexpectedly, not in their change over time. Although the growth models fit the data well, significant residual variances in the latent factors remain.

  3. A Research Paper on Simulation Model for Teaching and Learning Process in Higher Education

    Directory of Open Access Journals (Sweden)

    S. S. Rai

    2014-06-01

    Full Text Available The Research paper entitled above gives trace on Simulation Model for Teaching and Learning. This is the important area in which the teaching and learning can be benefited. The teaching methods involve three types of methods like lecturing method; Computer based teaching method and mixed teaching methods. The researcher has studied the methods used by teachers and method preferred by the students they have also returned the rules to find out the quality of the teaching and learning. The results are found by Chi. Square test for the teaching and learning methods. The respondents taken for the study were 100 teachers and students were 100. The final results are very surprising and it suggests using both Computers based and lecturing method of teaching learning process. The simulation model is designed by the researcher to find out the best method of the teaching and learning process in higher education. The main objective of the paper is to trace on the best method of the teaching and learning so that the output of the teaching method is improved and students are benefited by this. The objectives of this paper are to study various types of teaching and learning methods used by higher educational Institutes, study the ideas and the best way of teaching suggested by expert teachers, to study the ideas of students who are good in learning and to develop a simulation model and verify using 100 examples for teaching and learning.

  4. Improved convergence and stability properties in a three-dimensional higher-order ice sheet model

    Directory of Open Access Journals (Sweden)

    J. J. Fürst

    2011-07-01

    Full Text Available We present a novel finite difference implementation of a three-dimensional higher-order ice sheet model that performs well both in terms of convergence rate and numerical stability. In order to achieve these benefits the discretisation of the governing force balance equation makes extensive use of information on staggered grid points. Using the same iterative solver, an existing discretisation that operates exclusively on the regular grid serves as a reference. Participation in the ISMIP-HOM benchmark indicates that both discretisations are capable of reproducing the higher-order model inter-comparison results. This allows a direct comparison not only of the resultant velocity fields but also of the solver's convergence behaviour which holds main differences. First and foremost, the new finite difference scheme facilitates convergence by a factor of up to 7 and 2.6 in average. In addition to this decrease in computational costs, the precision for the resultant velocity field can be chosen higher in the novel finite difference implementation. For high precisions, the old discretisation experiences difficulties to converge due to large variation in the velocity fields of consecutive Picard iterations. Finally, changing discretisation prevents build-up of local field irregularites that occasionally cause divergence of the solution for the reference discretisation.

    The improved behaviour makes the new discretisation more reliable for extensive application to real ice geometries. Higher precision and robust numerics are crucial in time dependent applications since numerical oscillations in the velocity field of subsequent time steps are attenuated and divergence of the solution is prevented. Transient applications also benefit from the increased computational efficiency.

  5. Stabilizing the electroweak vacuum by higher dimensional operators in a Higgs-Yukawa model

    Energy Technology Data Exchange (ETDEWEB)

    Hegde, Prasad [National Taiwan Univ., Taipei (China); Jansen, Karl [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany). John von Neumann-Inst. fuer Computing NIC; Lin, C.J. David [National Chaio Tung Univ., Hsinchu (China); Nagy, Attila [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany). John von Neumann-Inst. fuer Computing NIC; Humboldt-Universitaet, Berlin (Germany)

    2013-11-15

    The Higgs boson discovery at the LHC with a mass of approximately 126 GeV suggests, that the electroweak vacuum of the standard model may be metastable at very high energies. However, any new physics beyond the standard model can change this picture. We want to address this important question within a lattice Higgs-Yukawa model as the limit of the standard model (SM). In this framework we will probe the effect of a higher dimensional operator for which we take a ({phi}{sup {dagger}}{phi}){sup 3}-term. Such a term could easily originate as a remnant of physics beyond the SM at very large scales. As a first step we investigate the phase diagram of the model including such a ({phi}{sup {dagger}}{phi}){sup 3} operator. Exploratory results suggest the existence of regions in parameter space where first order transitions turn to second order ones, indicating the existence of a tri-critical line. We will explore the phase structure and the consequences for the stability of the SM, both analytically by investigating the constraint effective potential in lattice perturbation theory, and by studying the system non-perturbatively using lattice simulations.

  6. Modeling and analysis of smart piezoelectric beams using simple higher order shear deformation theory

    Science.gov (United States)

    Adnan Elshafei, M.; Alraiess, Fuzy

    2013-03-01

    In the current work, a finite element formulation is developed for modeling and analysis of isotropic as well as orthotropic composite beams with distributed piezoelectric actuators subjected to both mechanical and electrical loads. The proposed model is developed based on a simple higher order shear deformation theory where the displacement field equations in the model account for a parabolic distribution of the shear strain and the nonlinearity of in-plane displacements across the thickness and subsequently the shear correction factor is not involved. The virtual displacement method is used to formulate the equations of motion of the structure system. The model is valid for both segmented and continuous piezoelectric elements, which can be either surface bonded or embedded in the laminated beams. A two-node element with four mechanical degrees of freedom in addition to one electrical degree of freedom for each node is used in the finite element formulation. The electric potential is considered as a function of the thickness and the length of the beam element. A MATLAB code is developed to compute the static deformation and free vibration parameters of the beams with distributed piezoelectric actuators. The obtained results from the proposed model are compared with the available analytical results and the finite element results of other researchers.

  7. Higher Education: Commodity or Space for Learning: modelling contradictions in educational practices

    OpenAIRE

    Wihlborg, Monne; Nilsson, Monica

    2011-01-01

    In this article the authors reflect upon and critically examine signs of a contradiction in higher education which they discuss in terms of the tension between 'use value' and 'exchange value'. Use value here represents learning as something valuable ‘in itself’ whereas exchange value represents learning as an achievement of grades and credits to be ‘traded’ on a market. Their aim in this article is to present a model based on the concepts of use value and exchange value, clar...

  8. Higher derivative extensions of 3d Chern-Simons models: conservation laws and stability

    Energy Technology Data Exchange (ETDEWEB)

    Kaparulin, D.S.; Karataeva, I.Yu.; Lyakhovich, S.L. [Tomsk State University, Physics Faculty, Tomsk (Russian Federation)

    2015-11-15

    We consider the class of higher derivative 3d vector field models with the field equation operator being a polynomial of the Chern-Simons operator. For the nth-order theory of this type, we provide a general recipe for constructing n-parameter family of conserved second rank tensors. The family includes the canonical energy-momentum tensor, which is unbounded, while there are bounded conserved tensors that provide classical stability of the system for certain combinations of the parameters in the Lagrangian. We also demonstrate the examples of consistent interactions which are compatible with the requirement of stability. (orig.)

  9. A Simple Model of Separation Logic for Higher-order Store

    DEFF Research Database (Denmark)

    Birkedal, Lars; Reus, Bernhard; Schwinghammer, Jan;

    2008-01-01

    Separation logic is a Hoare-style logic for reasoning about pointer-manipulating programs. Its core ideas have recently been extended from low-level to richer, high-level languages. In this paper we develop a new semantics of the logic for a programming language where code can be stored (i.......e., with higher-order store). The main improvement on previous work is the simplicity of the model. As a consequence, several restrictions imposed by the semantics are removed, leading to a considerably more natural assertion language with a powerful specification logic....

  10. Nitrogen-gas bubbling during the cultivation of Clostridium tetani produces a higher yield of tetanus toxin for the preparation of its toxoid.

    Science.gov (United States)

    De Luca, M M; Abeiro, H D; Bernagozzi, J A; Basualdo, J A

    1997-01-01

    We investigated the effect of exposing cultures of Clostridium tetani to nitrogen (N2) gas on the recovery of tetanus toxin to be processed for the preparation of its toxoid. N2 was bubbled through nine 10-liter cultures during the growth of the bacteria, while nine parallel control incubations were maintained without bubbling. We found that treatment of the C. tetani anaerobes with an inert gas in this manner during cultivation produced a highly significant increase in the yield of tetanus toxin from them in comparison with the standard procedure.

  11. A Study of Enhanced, Higher Order Boussinesq-Type Equations and Their Numerical Modelling

    DEFF Research Database (Denmark)

    Banijamali, Babak

    potential for applications to the realm of numerical modelling in coastal engineering. The derivation and analysis of several forms of higher-order in dispersion and non-linearity Boussinesq-type equations have been undertaken, obtaining and investigating the properties of a new and generalised class...... discretisation methods. The analysis categorises the errors of the semidiscretised and the fully-discretised equations into the categories of spurious dispersion and spurious diffusion. In particular, issues of numerical wave refraction and numerical wave blocking are introduced and addressed in the contexts...... is realizable. These tests also provided a venue for the practical investigation of the linear and nonlinear properties of the numerical models in the sense of the type of discretisations. Similarly, the applications to the propagation over the focusing bathymetry of Whalin (1971) was a similar venue...

  12. Estimating potential saving with energy consumption behaviour model in higher education institutions

    Directory of Open Access Journals (Sweden)

    Mohd Hafizal Ishak

    2016-11-01

    Full Text Available Towards sustainable Higher Education Institutions (HEIs, energy consumption behaviour is one of several issues that require an attention by facilities manager. Information from the behavioural aspect would be useful for facilities manager on managing the energy and determining potential energy saving. A lack of information negatively affects this aim. Hence, this paper proposes a methodology for assessing the energy consumption behaviour with the objective determining potential energy saving. The method used energy culture framework as basis and joined with centrographic approach and multiple-regression analysis. A self-administrated survey carried out involving 1400 respondents in selected HEIs. There are four types of energy use among students in HEIs namely, 'high', 'low', ‘medium’ and 'conserve' determined from the centrographic analysis. The energy consumption behaviour model was developed and tested against the holdout sample. Through the model's application, there is a vast potential for energy savings with over 55 kWh daily among the students.

  13. The Design Model of Multilevel Estimation Means for Students’ Competence Assessment at Technical Higher School

    Directory of Open Access Journals (Sweden)

    O. F. Shikhova

    2012-01-01

    Full Text Available The paper considers the research findings aimed at the developing the new quality testing technique for students assessment at Technical Higher School. The model of multilevel estimation means is provided for diagnosing the level of general cultural and professional competences of students doing a bachelor degree in technological fields. The model implies the integrative character of specialists training - the combination of both the psycho-pedagogic (invariable and engineering (variable components, as well as the qualimetric approach substantiating the system of students competence estimation and providing the most adequate assessment means. The principles of designing the multilevel estimation means are defined along with the methodology approaches to their implementation. For the reasonable selection of estimation means, the system of quality criteria is proposed by the authors, being based on the group expert assessment. The research findings can be used for designing the competence-oriented estimation means. 

  14. Experimental modeling of polymer latex spray coating for producing controlled-release urea

    Institute of Scientific and Technical Information of China (English)

    Rui Lan; Yonghui Liu; Guanda Wang; Tingjie Wang; Chengyou Kan; Yong Jin

    2011-01-01

    Spray coating of polymer latex onto fertilizer particles in a fluidized bed for producing controlled-release urea is an environment friendly technology as it does not need any toxic organic solvent.Since the spray coating process in a fluidized bed occurs in the presence of particle collisions,the coating of the particles is random,intermittent and multiple,thus making it difficult to investigate the film formation process.In this paper,an experimental model apparatus was designed and used to investigate the effects of the key factors in the spray coating process.This apparatus reasonably simplified the complex process to avoid particle collisions and randomness in the coating.The intermittent coating in the fluidized bed was modeled by periodic coating and dewatering in the experimental apparatus.A large area film was obtained,and the film permeability was measured.The effects of atomizing gas flow rate,spray rate of latex,solid content of latex and gas temperature on film structure and film permeability were investigated.It was found that water transfer played a dominant role in the spray coating process.

  15. A Parametric Sizing Model for Molten Regolith Electrolysis Reactors to Produce Oxygen from Lunar Regolith

    Science.gov (United States)

    Schreiner, Samuel S.; Dominguez, Jesus A.; Sibille, Laurent; Hoffman, Jeffrey A.

    2015-01-01

    We present a parametric sizing model for a Molten Electrolysis Reactor that produces oxygen and molten metals from lunar regolith. The model has a foundation of regolith material properties validated using data from Apollo samples and simulants. A multiphysics simulation of an MRE reactor is developed and leveraged to generate a vast database of reactor performance and design trends. A novel design methodology is created which utilizes this database to parametrically design an MRE reactor that 1) can sustain the required mass of molten regolith, current, and operating temperature to meet the desired oxygen production level, 2) can operate for long durations via joule heated, cold wall operation in which molten regolith does not touch the reactor side walls, 3) can support a range of electrode separations to enable operational flexibility. Mass, power, and performance estimates for an MRE reactor are presented for a range of oxygen production levels. The effects of several design variables are explored, including operating temperature, regolith type/composition, batch time, and the degree of operational flexibility.

  16. Higher Spin Currents in the N=2 Stringy Coset Minimal Model

    CERN Document Server

    Ahn, Changhyun

    2016-01-01

    In the coset model based on (A_{N-1}^{(1)} \\oplus A_{N-1}^{(1)}, A_{N-1}^{(1)}) at level (N, N; 2N), it is known that the N=2 superconformal algebra can be realized by the two kinds of adjoint fermions. Each Kac-Moody current of spin-1 is given by the product of fermions with structure constant (f symbols) as usual. One can construct the spin-1 current by combining the above two fermions with the structure constant and the spin-1 current by multiplying these two fermions with completely symmetric SU(N) invariant tensor of rank 3 (d symbols). The lowest higher spin-2 current with nonzero U(1) charge (corresponding to the zeromode eigenvalue of spin-1 current of N=2 superconformal algebra) can be obtained from these four spin-1 currents in quadratic form. Similarly, the other type of lowest higher spin-2 current, whose U(1) charge is opposite to the above one, can be obtained also. Four higher spin-5/2 currents can be constructed from the operator product expansions (OPEs) between the spin-3/2 currents of N=2 s...

  17. The impact of an international online accreditation system on pedagogical models and strategies in higher education

    Directory of Open Access Journals (Sweden)

    Garista Patrizia

    2015-06-01

    Full Text Available Health promotion practice is characterised by a diverse workforce drawn from a broad range of disciplines, bringing together an extensive breadth of knowledge, skills, abilities, attitudes and values stemming from biomedical and social science frameworks. One of the goals of the CompHP Project was to ensure that higher education training would not only reach competency-based standards necessary for best practice, but also facilitate mobility within the EU and beyond through the accreditation of professional practitioners and educational courses. As a result, higher education institutions in Italy and elsewhere are requested to shift the focus from the definition of learning objectives to the identification of teaching strategies and assessment measures to guarantee that students have acquired the competencies identified. This requires reflection on the pedagogical models underpinning course curricula and teaching–learning approaches in higher education, not only to meet the competency-based standards but also to incorporate overarching transversal competencies inherent to the profession and, more specifically, to the online accreditation procedure. Professionals applying for registration require competence in foreign languages, metacognition and be digitally literate. The article provides a brief overview of the development and structure of the International Union for Health Promotion and Education online accreditation system and proposes a pedagogical reflection on course curricula.

  18. Application of higher-order KdV-mKdV model with higher-degree nonlinear terms to gravity waves in atmosphere

    Institute of Scientific and Technical Information of China (English)

    Li Zi-Liang

    2009-01-01

    Higher-order Korteweg-de Vries (KdV)-modified KdV (mKdV) equations with a higher-degree of nonlinear terms are derived from a simple incompressible non-hydrostatic Boussinesq equation set in atmosphere and are used to investigate gravity waves in atmosphere. By taking advantage of the auxiliary nonlinear ordinary differential equation, periodic wave and solitary wave solutions of the fifth-order KdV-mKdV models with higher-degree nonlinear terms are obtained under some constraint conditions. The analysis shows that the propagation and the periodic structures of gravity waves depend on the properties of the slope of line of constant phase and atmospheric stability. The Jacobi elliptic function wave and solitary wave solutions with slowly varying amplitude are transformed into triangular waves with the abruptly varying amplitude and breaking gravity waves under the effect of atmospheric instability.

  19. A higher order conditional random field model for simultaneous classification of land cover and land use

    Science.gov (United States)

    Albert, Lena; Rottensteiner, Franz; Heipke, Christian

    2017-08-01

    We propose a new approach for the simultaneous classification of land cover and land use considering spatial as well as semantic context. We apply a Conditional Random Fields (CRF) consisting of a land cover and a land use layer. In the land cover layer of the CRF, the nodes represent super-pixels; in the land use layer, the nodes correspond to objects from a geospatial database. Intra-layer edges of the CRF model spatial dependencies between neighbouring image sites. All spatially overlapping sites in both layers are connected by inter-layer edges, which leads to higher order cliques modelling the semantic relation between all land cover and land use sites in the clique. A generic formulation of the higher order potential is proposed. In order to enable efficient inference in the two-layer higher order CRF, we propose an iterative inference procedure in which the two classification tasks mutually influence each other. We integrate contextual relations between land cover and land use in the classification process by using contextual features describing the complex dependencies of all nodes in a higher order clique. These features are incorporated in a discriminative classifier, which approximates the higher order potentials during the inference procedure. The approach is designed for input data based on aerial images. Experiments are carried out on two test sites to evaluate the performance of the proposed method. The experiments show that the classification results are improved compared to the results of a non-contextual classifier. For land cover classification, the result is much more homogeneous and the delineation of land cover segments is improved. For the land use classification, an improvement is mainly achieved for land use objects showing non-typical characteristics or similarities to other land use classes. Furthermore, we have shown that the size of the super-pixels has an influence on the level of detail of the classification result, but also on the

  20. Fused RSOS Lattice Models as Higher-Level Nonunitary Minimal Cosets

    CERN Document Server

    Tartaglia, Elena

    2015-01-01

    We consider the Forrester-Baxter RSOS lattice models with crossing parameter $\\lambda=(m'\\!-\\!m)\\pi/m'$ in Regime~III. In the continuum scaling limit, these models are described by the minimal models ${\\cal M}(m,m')$. We conjecture that, for $\\lambda<\\pi/n$, the $n\\times n$ fused RSOS models with $n\\ge 2$ are described by the higher-level coset $(A^{(1)}_1)_k\\otimes (A^{(1)}_1)_n/(A^{(1)}_1)_{k+n}$ at fractional level $k=nM/(M'\\!-\\!M)-2$ with $(M,M')=\\big(nm-(n\\!-\\!1)m',m'\\big)$. To support this conjecture, we investigate the one-dimensional sums arising from Baxter's off-critical corner transfer matrices. In unitary cases ($m=m'\\!-\\!1$) it is known that, up to leading powers of $q$, these coincide with the branching functions $b_{r,s,\\ell}^{m'\\!-n,m'\\!,n}(q)$. For general nonunitary cases ($m

  1. New higher-order Godunov code for modelling performance of two-stage light gas guns

    Science.gov (United States)

    Bogdanoff, D. W.; Miller, R. J.

    1995-01-01

    A new quasi-one-dimensional Godunov code for modeling two-stage light gas guns is described. The code is third-order accurate in space and second-order accurate in time. A very accurate Riemann solver is used. Friction and heat transfer to the tube wall for gases and dense media are modeled and a simple nonequilibrium turbulence model is used for gas flows. The code also models gunpowder burn in the first-stage breech. Realistic equations of state (EOS) are used for all media. The code was validated against exact solutions of Riemann's shock-tube problem, impact of dense media slabs at velocities up to 20 km/sec, flow through a supersonic convergent-divergent nozzle and burning of gunpowder in a closed bomb. Excellent validation results were obtained. The code was then used to predict the performance of two light gas guns (1.5 in. and 0.28 in.) in service at the Ames Research Center. The code predictions were compared with measured pressure histories in the powder chamber and pump tube and with measured piston and projectile velocities. Very good agreement between computational fluid dynamics (CFD) predictions and measurements was obtained. Actual powder-burn rates in the gun were found to be considerably higher (60-90 percent) than predicted by the manufacturer and the behavior of the piston upon yielding appears to differ greatly from that suggested by low-strain rate tests.

  2. Managing maritime automobile terminals: an approach toward decision-support model for higher productivity

    Directory of Open Access Journals (Sweden)

    Bojan Beškovnik

    2011-12-01

    Full Text Available The article describes actions and strategies to obtain higher productivity on maritime automobile terminals. The main focus is on elaboration of efficient and effective organizational structure to model and implement short-term, mid-term and long-term strategies. In addition, with an empiric approach we combined the analyses of current findings in important scientific papers and our acknowledgments in practical research of north Adriatic maritime automobile terminals. The main goal is to propose actions towards increasing system's productivity. Based on our research of the north Adriatic maritime automobile terminals and with Lambert's model an in-deep analysis of limiting factors, user's expectations and possibilities for productivity increase has been performed. Moreover, with our acknowledgments a three-level decision-support model is presented. With an adequate model implementation it is possible to efficiently develop and implement different strategies of productivity measurement and productivity increase, especially in the fields of internal transport productivity, entrance/exit truck gates operations and wagon manipulations. According to our observation a significant increase might be achieved in all three fields.

  3. 高阶非局部变分模型%Higher-order nonlocal variational model

    Institute of Scientific and Technical Information of China (English)

    李亚峰; 冯象初

    2012-01-01

    To describe the nonlocal structure of images better and remove noise, this paper proposes a higher-order nonlocal variational model by defining a new weighted function. Theoretical analysis and numerical experiments are presented to demonstrate the performance of the proposed model, which is better than the original in terms of both PSNR and visual perception. As a result, the new model keeps the advantages of the nonlocal variational model, while it can preserve image features better.%为了更好地描述图像的非局部结构并抑制噪声,通过定义新的权函数,提出了一个高阶非局部变分模型.理论分析和实验结果表明,相比于非局部平均去噪算子和非局部变分模型,提出的高阶非局部变分模型在去噪结果上有更高的信噪比和更好的视觉效果.因此,新模型保持了非局部变分模型的优点,同时能够更好地保留图像特征.

  4. A model for analysing factors which may influence quality management procedures in higher education

    Directory of Open Access Journals (Sweden)

    Cătălin MAICAN

    2015-12-01

    Full Text Available In all universities, the Office for Quality Assurance defines the procedure for assessing the performance of the teaching staff, with a view to establishing students’ perception as regards the teachers’ activity from the point of view of the quality of the teaching process, of the relationship with the students and of the assistance provided for learning. The present paper aims at creating a combined model for evaluation, based on Data Mining statistical methods: starting from the findings revealed by the evaluations teachers performed to students, using the cluster analysis and the discriminant analysis, we identified the subjects which produced significant differences between students’ grades, subjects which were subsequently subjected to an evaluation by students. The results of these analyses allowed the formulation of certain measures for enhancing the quality of the evaluation process.

  5. An accurate higher order displacement model with shear and normal deformations effects for functionally graded plates

    Energy Technology Data Exchange (ETDEWEB)

    Jha, D.K., E-mail: dkjha@barc.gov.in [Civil Engineering Division, Bhabha Atomic Research Centre, Trombay, Mumbai 400 085 (India); Kant, Tarun [Department of Civil Engineering, Indian Institute of Technology Bombay, Powai, Mumbai 400 076 (India); Srinivas, K. [Civil Engineering Division, Bhabha Atomic Research Centre, Mumbai 400 085 (India); Singh, R.K. [Reactor Safety Division, Bhabha Atomic Research Centre, Mumbai 400 085 (India)

    2013-12-15

    Highlights: • We model through-thickness variation of material properties in functionally graded (FG) plates. • Effect of material grading index on deformations, stresses and natural frequency of FG plates is studied. • Effect of higher order terms in displacement models is studied for plate statics. • The benchmark solutions for the static analysis and free vibration of thick FG plates are presented. -- Abstract: Functionally graded materials (FGMs) are the potential candidates under consideration for designing the first wall of fusion reactors with a view to make best use of potential properties of available materials under severe thermo-mechanical loading conditions. A higher order shear and normal deformations plate theory is employed for stress and free vibration analyses of functionally graded (FG) elastic, rectangular, and simply (diaphragm) supported plates. Although FGMs are highly heterogeneous in nature, they are generally idealized as continua with mechanical properties changing smoothly with respect to spatial coordinates. The material properties of FG plates are assumed here to vary through thickness of plate in a continuous manner. Young's modulii and material densities are considered to be varying continuously in thickness direction according to volume fraction of constituents which are mathematically modeled here as exponential and power law functions. The effects of variation of material properties in terms of material gradation index on deformations, stresses and natural frequency of FG plates are investigated. The accuracy of present numerical solutions has been established with respect to exact three-dimensional (3D) elasticity solutions and the other models’ solutions available in literature.

  6. Use of simulation models to study the dynamic of recall of non-conform perishable produce through the supply chain

    DEFF Research Database (Denmark)

    Busato, P.; Sopegno, A.; Berruto, R.

    2013-01-01

    together to form a large size lot at some points in the supply-chain. Larger lot size could imply higher risk for the consumers in case of recall of the produce and much higher recall time and cost for the supply-chain. When a non-conformity occurs, the time to recall the produce depends on many factors...... the consumer. Each of these is a system itself that interacts with the other components of the supply-chain. The nonconformity could occur in each of these links. Because of processing plant requirement, storage requirements, and because of savings in the traceability process, often small size lots are merged...

  7. Numerical modeling of initiation of lightning leaders from tall structures by sprite-producing lightning discharges

    Science.gov (United States)

    Pasko, V. P.

    2011-12-01

    It is well established by now that large charge transfers between cloud and ground in positive cloud-to-ground lightning discharges (+CGs) can lead to transient electric field enhancements at mesospheric and lower ionospheric altitudes. In these events the electric field can exceed the conventional breakdown field and lead to formation of transient luminous events referred to as sprites and sprite halos [e.g., Qin et al., JGR, 116, A06305, 2011, and references therein]. Stanley and Heavner [Proc. 12th International Conference on Atmospheric Electricity, Versailles, France, 2003] reported that the large and rapid charge transfer of +CGs producing sprites can also initiate upward positive leaders from tall structures. These authors also presented data analysis indicating that structures with >400 m height have a significantly enhanced probability of launching upward positive leaders that may culminate in a -CG return stroke to the structure. The effect can be understood by considering the field intensification at the top of the tall structure combined with fast application of the field preventing formation and shielding effects of ion corona [Brook et al., JGR, 66, 3967, 1961]. In the present work we utilize the most recent modeling approaches developed at Penn State [e.g., Riousset et al., JGR, 115, A00E10, 2010] to quantify the conditions leading to initiation of positive leaders from tall structures following sprite-producing +CGs. Experiments show that the streamer zone transforms into leader when voltage drop along the streamer zone exceeds 400 kV [e.g., Aleksandrov et al., J. Phys. D: Appl. Phys., 38, 1225, 2005]. For a formed leader half of the voltage drops in the streamer zone, and another half in free space ahead of the streamer zone [Bazelyan and Raizer, Lightning physics and lightning protection, p. 62, 2000]. In our analysis therefore we assume that minimum voltage at the tip of the tower should exceed 800 kV for sustainment of upward propagating leader

  8. Activity of Antimicrobial Combinations against KPC-2-Producing Klebsiella pneumoniae in a Rat Model and Time-Kill Assay

    Science.gov (United States)

    Aranha Junior, Ayrton Alves; Arend, Lavinia Nery; Ribeiro, Vanessa; Zavascki, Alexandre Prehn; Tuon, Felipe Francisco

    2015-01-01

    This study evaluated the efficacy of tigecycline (TIG), polymyxin B (PMB), and meropenem (MER) in 80 rats challenged with Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae infection. A time-kill assay was performed with the same strain. Triple therapy and PMB+TIG were synergistic, promoted 100% survival, and produced negative peritoneal cultures, while MER+TIG showed lower survival and higher culture positivity than other regimens (P = 0.018) and was antagonistic. In vivo and in vitro studies showed that combined regimens, except MER+TIG, were more effective than monotherapies for this KPC-producing strain. PMID:25896686

  9. European model of satisfaction: a case study with students from a Higher Education Instituition

    Directory of Open Access Journals (Sweden)

    Everton Anger Cavalheiro

    2014-06-01

    Full Text Available This study aimed to evaluate the overall satisfaction determinants of the student’s body of a higher education institution in the northwest of Rio Grande do Sul/Brasil. To do so, a descriptive quantitative research was performed, which used a model based on a Survey with 402 students, being the instrument used to conduct the survey based on the European model of satisfaction. Represented by a structural equation (PASWAN YOUNG, 2002, apud VIEIRA et al., 2008, the ECSI (European Customer Satisfaction Model, focuses on: (i evaluating the influence of perceived quality, the expectation of quality, image and perceived value in the overall student satisfaction; (II evaluating the influence of the general satisfaction of students in the level of loyalty and retention of students in the educational institution, and (III pointing key areas as well as a set of indicators for the management and maintenance of the students’ satisfaction from the institution being analyzed. Thus, with the application of the instrument, three factors able to explain 78% of student’s satisfaction towards the university were found: the first and most representative factor was called the student perceived value, which is the perceived value or level of teaching quality for the price paid by the students, the second factor is the image of the university, and the third factor are the expectations of the student.

  10. Modeling Multi-Agent Self-Organization through the Lens of Higher Order Attractor Dynamics.

    Science.gov (United States)

    Butner, Jonathan E; Wiltshire, Travis J; Munion, A K

    2017-01-01

    Social interaction occurs across many time scales and varying numbers of agents; from one-on-one to large-scale coordination in organizations, crowds, cities, and colonies. These contexts, are characterized by emergent self-organization that implies higher order coordinated patterns occurring over time that are not due to the actions of any particular agents, but rather due to the collective ordering that occurs from the interactions of the agents. Extant research to understand these social coordination dynamics (SCD) has primarily examined dyadic contexts performing rhythmic tasks. To advance this area of study, we elaborate on attractor dynamics, our ability to depict them visually, and quantitatively model them. Primarily, we combine difference/differential equation modeling with mixture modeling as a way to infer the underlying topological features of the data, which can be described in terms of attractor dynamic patterns. The advantage of this approach is that we are able to quantify the self-organized dynamics that agents exhibit, link these dynamics back to activity from individual agents, and relate it to other variables central to understanding the coordinative functionality of a system's behavior. We present four examples that differ in the number of variables used to depict the attractor dynamics (1, 2, and 6) and range from simulated to non-simulated data sources. We demonstrate that this is a flexible method that advances scientific study of SCD in a variety of multi-agent systems.

  11. Thermodynamics and higher order moments in SU(3) linear σ-model with gluonic quasiparticles

    Science.gov (United States)

    Nasser Tawfik, Abdel; Magdy, Niseem

    2015-01-01

    In the framework of the linear σ-model (LSM) with three quark flavors, the chiral phase diagram at finite temperature and density is investigated. For temperatures higher than the critical temperature ({{T}c}), we added to the LSM the gluonic sector from the quasi-particle model (QPM), which assumes that the interacting gluons in the strongly interacting matter, the quark-gluon plasma (QGP), are phenomenologically the same as non-interacting massive quasi-particles. The dependence of the chiral condensates of strange and non-strange quarks on the temperature and chemical potential is analyzed. Then, we calculate the thermodynamics in the new approach (using a combination of the LSM and the QPM). Confronting the results with those from recent lattice quantum chromodynamics simulations reveals an excellent agreement for almost all thermodynamic quantities. The dependences of the first-order and second-order moments of the particle multiplicity on the chemical potential at fixed temperature are studied. These investigations are implemented through characterizing the large fluctuations accompanying the chiral phase transition. The results for the first-order and second-order moments are compared with those from the SU(3) Polyakov linear σ-model (PLSM). Also, the resulting phase diagrams deduced in the PLSM and the LSM+QPM are compared with each other.

  12. A participative evaluation model to refine academic support for first year Indigenous higher education students

    Directory of Open Access Journals (Sweden)

    Bronwyn Rossingh

    2012-03-01

    Full Text Available This paper presents an evaluative approach designed to provide a cycle of continuous improvement to retain Indigenous students during their first year of higher education.   The evaluation model operates in conjunction with a student academic enrichment program that is premised on valuing and respecting each student's background and life experience whilst building capability for learning success.  Data collected will be used for continual improvement of a newly developed innovative academic enrichment program that caters to the needs of Indigenous students.  The defining mechanisms of the model for measuring the first year experience are particularly meaningful for the Australian Centre For Indigenous Knowledges and Education as it moves into its inaugural year of operation in 2012. This preeminent time requires a flexible model to receive timely feedback in a reflexive environment where students guide the process as they continue their journey of accumulating knowledge and leave behind their contribution in shaping the landscape for future first year Indigenous students.  

  13. Selecting elephant grass families and progenies to produce bioenergy through mixed models (REML/BLUP).

    Science.gov (United States)

    Rodrigues, E V; Daher, R F; Dos Santos, A; Vivas, M; Machado, J C; Gravina, G do A; de Souza, Y P; Vidal, A K; Rocha, A Dos S; Freitas, R S

    2017-05-18

    Brazil has great potential to produce bioenergy since it is located in a tropical region that receives high incidence of solar energy and presents favorable climatic conditions for such purpose. However, the use of bioenergy in the country is below its productivity potential. The aim of the current study was to select full-sib progenies and families of elephant grass (Pennisetum purpureum S.) to optimize phenotypes relevant to bioenergy production through mixed models (REML/BLUP). The circulating diallel-based crossing of ten elephant grass genotypes was performed. An experimental design using the randomized block methodology, with three repetitions, was set to assess both the hybrids and the parents. Each plot comprised 14-m rows, 1.40 m spacing between rows, and 1.40 m spacing between plants. The number of tillers, plant height, culm diameter, fresh biomass production, dry biomass rate, and the dry biomass production were assessed. Genetic-statistical analyses were performed through mixed models (REML/BLUP). The genetic variance in the assessed families was explained through additive genetic effects and dominance genetic effects; the dominance variance was prevalent. Families such as Capim Cana D'África x Guaçu/I.Z.2, Cameroon x Cuba-115, CPAC x Cuba-115, Cameroon x Guaçu/I.Z.2, and IAC-Campinas x CPAC showed the highest dry biomass production. The family derived from the crossing between Cana D'África and Guaçu/I.Z.2 showed the largest number of potential individuals for traits such as plant height, culm diameter, fresh biomass production, dry biomass production, and dry biomass rate. The individual 5 in the family Cana D'África x Guaçu/I.Z.2, planted in blocks 1 and 2, showed the highest dry biomass production.

  14. Levetiracetam synergises with common analgesics in producing antinociception in a mouse model of painful diabetic neuropathy.

    Science.gov (United States)

    Micov, Ana; Tomić, Maja; Pecikoza, Uroš; Ugrešić, Nenad; Stepanović-Petrović, Radica

    2015-07-01

    Painful diabetic neuropathy is difficult to treat. Single analgesics often have insufficient efficacy and poor tolerability. Combination therapy may therefore be of particular benefit, because it might provide optimal analgesia with fewer adverse effects. This study aimed to examine the type of interaction between levetiracetam, a novel anticonvulsant with analgesic properties, and commonly used analgesics (ibuprofen, aspirin and paracetamol) in a mouse model of painful diabetic neuropathy. Diabetes was induced in C57BL/6 mice with a single high dose of streptozotocin, applied intraperitoneally (150 mg/kg). Thermal (tail-flick test) and mechanical (electronic von Frey test) nociceptive thresholds were measured before and three weeks after diabetes induction. The antinociceptive effects of orally administered levetiracetam, analgesics, and their combinations were examined in diabetic mice that developed thermal/mechanical hypersensitivity. In combination experiments, the drugs were co-administered in fixed-dose fractions of single drug ED50 and the type of interaction was determined by isobolographic analysis. Levetiracetam (10-100 mg/kg), ibuprofen (2-50 mg/kg), aspirin (5-75 mg/kg), paracetamol (5-100 mg/kg), and levetiracetam-analgesic combinations produced significant, dose-dependent antinociceptive effects in diabetic mice in both tests. In the tail-flick test, isobolographic analysis revealed 15-, and 19-fold reduction of doses of both drugs in the combination of levetiracetam with aspirin/ibuprofen, and paracetamol, respectively. In the von Frey test, approximately 7- and 9-fold reduction of doses of both drugs was detected in levetiracetam-ibuprofen and levetiracetam-aspirin/levetiracetam-paracetamol combinations, respectively. These results show synergism between levetiracetam and ibuprofen/aspirin/paracetamol in a model of painful diabetic neuropathy and might provide a useful approach to the treatment of patients suffering from painful diabetic neuropathy.

  15. Subject-specific tendon-aponeurosis definition in Hill-type model predicts higher muscle forces in dynamic tasks.

    Directory of Open Access Journals (Sweden)

    Pauline Gerus

    Full Text Available Neuromusculoskeletal models are a common method to estimate muscle forces. Developing accurate neuromusculoskeletal models is a challenging task due to the complexity of the system and large inter-subject variability. The estimation of muscles force is based on the mechanical properties of tendon-aponeurosis complex. Most neuromusculoskeletal models use a generic definition of the tendon-aponeurosis complex based on in vitro test, perhaps limiting their validity. Ultrasonography allows subject-specific estimates of the tendon-aponeurosis complex's mechanical properties. The aim of this study was to investigate the influence of subject-specific mechanical properties of the tendon-aponeurosis complex on a neuromusculoskeletal model of the ankle joint. Seven subjects performed isometric contractions from which the tendon-aponeurosis force-strain relationship was estimated. Hopping and running tasks were performed and muscle forces were estimated using subject-specific tendon-aponeurosis and generic tendon properties. Two ultrasound probes positioned over the muscle-tendon junction and the mid-belly were combined with motion capture to estimate the in vivo tendon and aponeurosis strain of the medial head of gastrocnemius muscle. The tendon-aponeurosis force-strain relationship was scaled for the other ankle muscles based on tendon and aponeurosis length of each muscle measured by ultrasonography. The EMG-driven model was calibrated twice - using the generic tendon definition and a subject-specific tendon-aponeurosis force-strain definition. The use of subject-specific tendon-aponeurosis definition leads to a higher muscle force estimate for the soleus muscle and the plantar-flexor group, and to a better model prediction of the ankle joint moment compared to the model estimate which used a generic definition. Furthermore, the subject-specific tendon-aponeurosis definition leads to a decoupling behaviour between the muscle fibre and muscle-tendon unit

  16. Subject-specific tendon-aponeurosis definition in Hill-type model predicts higher muscle forces in dynamic tasks.

    Science.gov (United States)

    Gerus, Pauline; Rao, Guillaume; Berton, Eric

    2012-01-01

    Neuromusculoskeletal models are a common method to estimate muscle forces. Developing accurate neuromusculoskeletal models is a challenging task due to the complexity of the system and large inter-subject variability. The estimation of muscles force is based on the mechanical properties of tendon-aponeurosis complex. Most neuromusculoskeletal models use a generic definition of the tendon-aponeurosis complex based on in vitro test, perhaps limiting their validity. Ultrasonography allows subject-specific estimates of the tendon-aponeurosis complex's mechanical properties. The aim of this study was to investigate the influence of subject-specific mechanical properties of the tendon-aponeurosis complex on a neuromusculoskeletal model of the ankle joint. Seven subjects performed isometric contractions from which the tendon-aponeurosis force-strain relationship was estimated. Hopping and running tasks were performed and muscle forces were estimated using subject-specific tendon-aponeurosis and generic tendon properties. Two ultrasound probes positioned over the muscle-tendon junction and the mid-belly were combined with motion capture to estimate the in vivo tendon and aponeurosis strain of the medial head of gastrocnemius muscle. The tendon-aponeurosis force-strain relationship was scaled for the other ankle muscles based on tendon and aponeurosis length of each muscle measured by ultrasonography. The EMG-driven model was calibrated twice - using the generic tendon definition and a subject-specific tendon-aponeurosis force-strain definition. The use of subject-specific tendon-aponeurosis definition leads to a higher muscle force estimate for the soleus muscle and the plantar-flexor group, and to a better model prediction of the ankle joint moment compared to the model estimate which used a generic definition. Furthermore, the subject-specific tendon-aponeurosis definition leads to a decoupling behaviour between the muscle fibre and muscle-tendon unit in agreement with

  17. Search for standard model Higgs bosons produced in association with W bosons.

    Science.gov (United States)

    Aaltonen, T; Adelman, J; Akimoto, T; Albrow, M G; González, B Alvarez; Amerio, S; Amidei, D; Anastassov, A; Annovi, A; Antos, J; Aoki, M; Apollinari, G; Apresyan, A; Arisawa, T; Artikov, A; Ashmanskas, W; Attal, A; Aurisano, A; Azfar, F; Azzi-Bacchetta, P; Azzurri, P; Bacchetta, N; Badgett, W; Barbaro-Galtieri, A; Barnes, V E; Barnett, B A; Baroiant, S; Bartsch, V; Bauer, G; Beauchemin, P-H; Bedeschi, F; Bednar, P; Behari, S; Bellettini, G; Bellinger, J; Belloni, A; Benjamin, D; Beretvas, A; Beringer, J; Berry, T; Bhatti, A; Binkley, M; Bisello, D; Bizjak, I; Blair, R E; Blocker, C; Blumenfeld, B; Bocci, A; Bodek, A; Boisvert, V; Bolla, G; Bolshov, A; Bortoletto, D; Boudreau, J; Boveia, A; Brau, B; Bridgeman, A; Brigliadori, L; Bromberg, C; Brubaker, E; Budagov, J; Budd, H S; Budd, S; Burkett, K; Busetto, G; Bussey, P; Buzatu, A; Byrum, K L; Cabrera, S; Campanelli, M; Campbell, M; Canelli, F; Canepa, A; Carlsmith, D; Carosi, R; Carrillo, S; Carron, S; Casal, B; Casarsa, M; Castro, A; Catastini, P; Cauz, D; Cavalli-Sforza, M; Cerri, A; Cerrito, L; Chang, S H; Chen, Y C; Chertok, M; Chiarelli, G; Chlachidze, G; Chlebana, F; Cho, K; Chokheli, D; Chou, J P; Choudalakis, G; Chuang, S H; Chung, K; Chung, W H; Chung, Y S; Ciobanu, C I; Ciocci, M A; Clark, A; Clark, D; Compostella, G; Convery, M E; Conway, J; Cooper, B; Copic, K; Cordelli, M; Cortiana, G; Crescioli, F; Almenar, C Cuenca; Cuevas, J; Culbertson, R; Cully, J C; Dagenhart, D; Datta, M; Davies, T; de Barbaro, P; De Cecco, S; Deisher, A; De Lentdecker, G; De Lorenzo, G; Dell'Orso, M; Demortier, L; Deng, J; Deninno, M; De Pedis, D; Derwent, P F; Di Giovanni, G P; Dionisi, C; Di Ruzza, B; Dittmann, J R; D'Onofrio, M; Donati, S; Dong, P; Donini, J; Dorigo, T; Dube, S; Efron, J; Erbacher, R; Errede, D; Errede, S; Eusebi, R; Fang, H C; Farrington, S; Fedorko, W T; Feild, R G; Feindt, M; Fernandez, J P; Ferrazza, C; Field, R; Flanagan, G; Forrest, R; Forrester, S; Franklin, M; Freeman, J C; Furic, I; Gallinaro, M; Galyardt, J; Garberson, F; Garcia, J E; Garfinkel, A F; Gerberich, H; Gerdes, D; Giagu, S; Giakoumopolou, V; Giannetti, P; Gibson, K; Gimmell, J L; Ginsburg, C M; Giokaris, N; Giordani, M; Giromini, P; Giunta, M; Glagolev, V; Glenzinski, D; Gold, M; Goldschmidt, N; Golossanov, A; Gomez, G; Gomez-Ceballos, G; Goncharov, M; González, O; Gorelov, I; Goshaw, A T; Goulianos, K; Gresele, A; Grinstein, S; Grosso-Pilcher, C; Grundler, U; Guimaraes da Costa, J; Gunay-Unalan, Z; Haber, C; Hahn, K; Hahn, S R; Halkiadakis, E; Hamilton, A; Han, B-Y; Han, J Y; Handler, R; Happacher, F; Hara, K; Hare, D; Hare, M; Harper, S; Harr, R F; Harris, R M; Hartz, M; Hatakeyama, K; Hauser, J; Hays, C; Heck, M; Heijboer, A; Heinemann, B; Heinrich, J; Henderson, C; Herndon, M; Heuser, J; Hewamanage, S; Hidas, D; Hill, C S; Hirschbuehl, D; Hocker, A; Hou, S; Houlden, M; Hsu, S-C; Huffman, B T; Hughes, R E; Husemann, U; Huston, J; Incandela, J; Introzzi, G; Iori, M; Ivanov, A; Iyutin, B; James, E; Jayatilaka, B; Jeans, D; Jeon, E J; Jindariani, S; Johnson, W; Jones, M; Joo, K K; Jun, S Y; Jung, J E; Junk, T R; Kamon, T; Kar, D; Karchin, P E; Kato, Y; Kephart, R; Kerzel, U; Khotilovich, V; Kilminster, B; Kim, D H; Kim, H S; Kim, J E; Kim, M J; Kim, S B; Kim, S H; Kim, Y K; Kimura, N; Kirsch, L; Klimenko, S; Klute, M; Knuteson, B; Ko, B R; Koay, S A; Kondo, K; Kong, D J; Konigsberg, J; Korytov, A; Kotwal, A V; Kraus, J; Kreps, M; Kroll, J; Krumnack, N; Kruse, M; Krutelyov, V; Kubo, T; Kuhlmann, S E; Kuhr, T; Kulkarni, N P; Kusakabe, Y; Kwang, S; Laasanen, A T; Lai, S; Lami, S; Lammel, S; Lancaster, M; Lander, R L; Lannon, K; Lath, A; Latino, G; Lazzizzera, I; LeCompte, T; Lee, J; Lee, J; Lee, Y J; Lee, S W; Lefèvre, R; Leonardo, N; Leone, S; Levy, S; Lewis, J D; Lin, C; Lin, C S; Linacre, J; Lindgren, M; Lipeles, E; Lister, A; Litvintsev, D O; Liu, T; Lockyer, N S; Loginov, A; Loreti, M; Lovas, L; Lu, R-S; Lucchesi, D; Lueck, J; Luci, C; Lujan, P; Lukens, P; Lungu, G; Lyons, L; Lys, J; Lysak, R; Lytken, E; Mack, P; MacQueen, D; Madrak, R; Maeshima, K; Makhoul, K; Maki, T; Maksimovic, P; Malde, S; Malik, S; Manca, G; Manousakis, A; Margaroli, F; Marino, C; Marino, C P; Martin, A; Martin, M; Martin, V; Martínez, M; Martínez-Ballarín, R; Maruyama, T; Mastrandrea, P; Masubuchi, T; Mattson, M E; Mazzanti, P; McFarland, K S; McIntyre, P; McNulty, R; Mehta, A; Mehtala, P; Menzemer, S; Menzione, A; Merkel, P; Mesropian, C; Messina, A; Miao, T; Miladinovic, N; Miles, J; Miller, R; Mills, C; Milnik, M; Mitra, A; Mitselmakher, G; Miyake, H; Moed, S; Moggi, N; Moon, C S; Moore, R; Morello, M; Fernandez, P Movilla; Mülmenstädt, J; Mukherjee, A; Muller, Th; Mumford, R; Murat, P; Mussini, M; Nachtman, J; Nagai, Y; Nagano, A; Naganoma, J; Nakamura, K; Nakano, I; Napier, A; Necula, V; Neu, C; Neubauer, M S; Nielsen, J; Nodulman, L; Norman, M; Norniella, O; Nurse, E; Oh, S H; Oh, Y D; Oksuzian, I; Okusawa, T; Oldeman, R; Orava, R; Osterberg, K; Griso, S Pagan; Pagliarone, C; Palencia, E; Papadimitriou, V; Papaikonomou, A; Paramonov, A A; Parks, B; Pashapour, S; Patrick, J; Pauletta, G; Paulini, M; Paus, C; Pellett, D E; Penzo, A; Phillips, T J; Piacentino, G; Piedra, J; Pinera, L; Pitts, K; Plager, C; Pondrom, L; Portell, X; Poukhov, O; Pounder, N; Prakoshyn, F; Pronko, A; Proudfoot, J; Ptohos, F; Punzi, G; Pursley, J; Rademacker, J; Rahaman, A; Ramakrishnan, V; Ranjan, N; Redondo, I; Reisert, B; Rekovic, V; Renton, P; Rescigno, M; Richter, S; Rimondi, F; Ristori, L; Robson, A; Rodrigo, T; Rogers, E; Rolli, S; Roser, R; Rossi, M; Rossin, R; Roy, P; Ruiz, A; Russ, J; Rusu, V; Saarikko, H; Safonov, A; Sakumoto, W K; Salamanna, G; Saltó, O; Santi, L; Sarkar, S; Sartori, L; Sato, K; Savoy-Navarro, A; Scheidle, T; Schlabach, P; Schmidt, E E; Schmidt, M A; Schmidt, M P; Schmitt, M; Schwarz, T; Scodellaro, L; Scott, A L; Scribano, A; Scuri, F; Sedov, A; Seidel, S; Seiya, Y; Semenov, A; Sexton-Kennedy, L; Sfyria, A; Shalhout, S Z; Shapiro, M D; Shears, T; Shepard, P F; Sherman, D; Shimojima, M; Shochet, M; Shon, Y; Shreyber, I; Sidoti, A; Siegrist, J; Sinervo, P; Sisakyan, A; Slaughter, A J; Slaunwhite, J; Sliwa, K; Smith, J R; Snider, F D; Snihur, R; Soderberg, M; Soha, A; Somalwar, S; Sorin, V; Spalding, J; Spinella, F; Spreitzer, T; Squillacioti, P; Stanitzki, M; St Denis, R; Stelzer, B; Stelzer-Chilton, O; Stentz, D; Strologas, J; Stuart, D; Suh, J S; Sukhanov, A; Sun, H; Suslov, I; Suzuki, T; Taffard, A; Takashima, R; Takeuchi, Y; Tanaka, R; Tecchio, M; Teng, P K; Terashi, K; Thom, J; Thompson, A S; Thompson, G A; Thomson, E; Tipton, P; Tiwari, V; Tkaczyk, S; Toback, D; Tokar, S; Tollefson, K; Tomura, T; Tonelli, D; Torre, S; Torretta, D; Tourneur, S; Trischuk, W; Tu, Y; Turini, N; Ukegawa, F; Uozumi, S; Vallecorsa, S; van Remortel, N; Varganov, A; Vataga, E; Vázquez, F; Velev, G; Vellidis, C; Veszpremi, V; Vidal, M; Vidal, R; Vila, I; Vilar, R; Vine, T; Vogel, M; Volobouev, I; Volpi, G; Würthwein, F; Wagner, P; Wagner, R G; Wagner, R L; Wagner-Kuhr, J; Wagner, W; Wakisaka, T; Wallny, R; Wang, S M; Warburton, A; Waters, D; Weinberger, M; Wester, W C; Whitehouse, B; Whiteson, D; Wicklund, A B; Wicklund, E; Williams, G; Williams, H H; Wilson, P; Winer, B L; Wittich, P; Wolbers, S; Wolfe, C; Wright, T; Wu, X; Wynne, S M; Yagil, A; Yamamoto, K; Yamaoka, J; Yamashita, T; Yang, C; Yang, U K; Yang, Y C; Yao, W M; Yeh, G P; Yoh, J; Yorita, K; Yoshida, T; Yu, G B; Yu, I; Yu, S S; Yun, J C; Zanello, L; Zanetti, A; Zaw, I; Zhang, X; Zheng, Y; Zucchelli, S; Group, R C

    2008-02-01

    We report on the results of a search for standard model Higgs bosons produced in association with W bosons from pp[over] collisions at sqrt[s]=1.96 TeV. The search uses a data sample corresponding to approximately 1 fb(-1) of integrated luminosity. Events consistent with the W-->lnu and H-->bb[over] signature are selected by triggering on a high-p(T) electron or muon candidate and tagging one or two of the jet candidates as having originated from b quarks. A neural network filter rejects a fraction of tagged charm and light-flavor jets, increasing the b-jet purity in the sample. We observe no excess lnubb[over] production beyond the background expectation, and we set 95% confidence level upper limits on the production cross section times branching fraction sigma(pp[over]-->WH)Br(H-->bb[over]) ranging from 3.9 to 1.3 pb, for specific Higgs boson mass hypotheses in the range 110 to 150 GeV/c2, respectively.

  18. Search for Standard Model Higgs Bosons Produced in Association with W Bosons

    CERN Document Server

    Aaltonen, T; Akimoto, T; Albrow, M G; Alvarez-Gonzalez, B; Amerio, S; Amidei, D; Anastassov, A; Annovi, A; Antos, J; Aoki, M; Apollinari, G; Apresyan, A; Arisawa, T; Artikov, A; Ashmanskas, W; Attal, A; Aurisano, A; Azfar, F; Azzi-Bacchetta, P; Azzurri, P; Bacchetta, N; Badgett, W; Barbaro-Galtieri, A; Barnes, V E; Barnett, B A; Baroiant, S; Bartsch, V; Bauer, G; Beauchemin, P H; Bedeschi, F; Bednar, P; Behari, S; Bellettini, G; Bellinger, J; Belloni, A; Benjamin, D; Beretvas, A; Beringer, J; Berry, T; Bhatti, A; Binkley, M; Bisello, D; Bizjak, I; Blair, R E; Blocker, C; Blumenfeld, B; Bocci, A; Bodek, A; Boisvert, V; Bölla, G; Bolshov, A; Bortoletto, D; Boudreau, J; Boveia, A; Brau, B; Bridgeman, A; Brigliadori, L; Bromberg, C; Brubaker, E; Budagov, Yu A; Budd, H S; Budd, S; Burkett, K; Busetto, G; Bussey, P; Buzatu, A; Byrum, K L; Cabrerar, S; Campanelli, M; Campbell, M; Canelli, F; Canepa, A; Carlsmith, D; Carosi, R; Carrillol, S; Carron, S; Casal, B; Casarsa, M; Castro, A; Catastini, P; Cauz, D; Cavalli-Sforza, M; Cerri, A; Cerritop, L; Chang, S H; Chen, Y C; Chertok, M; Chiarelli, G; Chlachidze, G; Chlebana, F; Cho, K; Chokheli, D; Chou, J P; Choudalakis, G; Chuang, S H; Chung, K; Chung, W H; Chung, Y S; Ciobanu, C I; Ciocci, M A; Clark, A; Clark, D; Compostella, G; Convery, M E; Conway, J; Cooper, B; Copic, K; Cordelli, M; Cortiana, G; Crescioli, F; Cuenca Almenarr, C; Cuevaso, J; Culbertson, R; Cully, J C; Dagenhart, D; Datta, M; Davies, T; De Barbaro, P; De Cecco, S; Deisher, A; De Lentdeckerd, G; De Lorenzo, G; Dell'Orso, Mauro; Demortier, L; Deng, J; Deninno, M; De Pedis, D; Derwent, P F; Di Giovanni, G P; Dionisi, C; Di Ruzza, B; Dittmann, J R; D'Onofrio, M; Donati, S; Dong, P; Donini, J; Dorigo, T; Dube, S; Efron, J; Erbacher, R; Errede, D; Errede, S; Eusebi, R; Fang, H C; Farrington, S; Fedorko, W T; Feild, R G; Feindt, M; Fernández, J P; Ferrazza, C; Field, R; Flanagan, G; Forrest, R; Forrester, S; Franklin, M; Freeman, J C; Furic, I; Gallinaro, M; Galyardt, J; Garberson, F; García, J E; Garfinkel, A F; Gerberich, H; Gerdes, D; Giagu, S; Giakoumopoloua, V; Giannetti, P; Gibson, K; Gimmell, J L; Ginsburg, C M; Giokarisa, N; Giordani, M; Giromini, P; Giunta, M; Glagolev, V; Glenzinski, D; Gold, M; Goldschmidt, N; Golossanov, A; Gómez, G; Gómez-Ceballos, G; Goncharov, M; Gonzlez, O; Gorelov, I; Goshaw, A T; Goulianos, K; Gresele, A; Grinstein, S; Grosso-Pilcher, C; Group, R C; Grundler, U; Guimaraesda Costa, J; Gunay-Unalan, Z; Haber, C; Hahn, K; Hahn, S R; Halkiadakis, E; Hamilton, A; Han, B Y; Han, J Y; Handler, R; Happacher, F; Hara, K; Hare, D; Hare, M; Harper, S; Harr, R F; Harris, R M; Hartz, M; Hatakeyama, K; Hauser, J; Hays, C; Heck, M; Heijboer, A; Heinemann, B; Heinrich, J; Henderson, C; Herndon, M; Heuser, J; Hewamanage, S; Hidas, D; Hillc, C S; Hirschbuehl, D; Höcker, A; Hou, S; Houlden, M; Hsu, S C; Huffman, B T; Hughes, R E; Husemann, U; Huston, J; Incandela, J; Introzzi, G; Iori, M; Ivanov, A; Iyutin, B; James, E; Jayatilaka, B; Jeans, D; Jeon, E J; Jindariani, S; Johnson, W; Jones, M; Joo, K K; Jun, S Y; Jung, J E; Junk, T R; Kamon, T; Kar, D; Karchin, P E; Kato, Y; Kephart, R; Kerzel, U; Khotilovich, V; Kilminster, B; Kim, D H; Kim, H S; Kim, J E; Kim, M J; Kim, S B; Kim, S H; Kim, Y K; Kimura, N; Kirsch, L; Klimenko, S; Klute, M; Knuteson, B; Ko, B R; Koay, S A; Kondo, K; Kong, D J; Konigsberg, J; Korytov, A; Kotwal, A V; Kraus, J; Kreps, M; Kroll, J; Krumnack, N; Kruse, M; Krutelyov, V; Kubo, T; Kuhlmann, S E; Kuhr, T; Kulkarni, N P; Kusakabe, Y; Kwang, S; Laasanen, A T; Lai, S; Lami, S; Lammel, S; Lancaster, M; Lander, R L; Lannon, K; Lath, A; Latino, G; Lazzizzera, I; Le Compte, T; Lee, J; Lee, J; Lee, Y J; Leeq, S W; Lefèvre, R; Leonardo, N; Leone, S; Levy, S; Lewis, J D; Lin, C; Lin, C S; Linacre, J; Lindgren, M; Lipeles, E; Lister, A; Litvintsev, D O; Liu, T; Lockyer, N S; Loginov, A; Loreti, M; Lovas, L; Lu, R S; Lucchesi, D; Lueck, J; Luci, C; Lujan, P; Lukens, P; Lungu, G; Lyons, L; Lys, J; Lysak, R; Lytken, E; Mack, P; MacQueen, D; Madrak, R; Maeshima, K; Makhoul, K; Mäki, T; Maksimovic, P; Malde, S; Malik, S; Manca, G; Manousakisa, A; Margaroli, F; Marino, C; Marino, C P; Martin, A; Martin, M; Martinj, V; Martínez, M; Martinez-Ballarin, R; Maruyama, T; Mastrandrea, P; Masubuchi, T; Mattson, M E; Mazzanti, P; McFarland, K S; McIntyre, P; McNultyi, R; Mehta, A; Mehtälä, P; Menzemerk, S; Menzione, A; Merkel, P; Mesropian, C; Messina, A; Miao, T; Miladinovic, N; Miles, J; Miller, R; Mills, C; Milnik, M; Mitra, A; Mitselmakher, G; Miyake, H; Moed, S; Moggi, N; Moon, C S; Moore, R; Morello, M; Movilla-Fernández, P A; Mulmenstdt, J; Mukherjee, A; Müller, T; Mumford, R; Murat, P; Mussini, M; Nachtman, J; Nagai, Y; Nagano, A; Naganoma, J; Nakamura, K; Nakano, I; Napier, A; Necula, V; Neu, C; Neubauer, M S; Nielsenf, J; Nodulman, L; Norman, M; Norniella, O; Nurse, E; Oh, S H; Oh, Y D; Oksuzian, I; Okusawa, T; Oldeman, R; Orava, R; Österberg, K; Pagan Griso, S; Pagliarone, C; Palencia, E; Papadimitriou, V; Papaikonomou, A; Paramonov, A A; Parks, B; Pashapour, S; Patrick, J; Pauletta, G; Paulini, M; Paus, C; Pellett, D E; Penzo, Aldo L; Phillips, T J; Piacentino, G; Piedra, J; Pinera, L; Pitts, K; Plager, C; Pondrom, L; Portell, X; Poukhov, O; Pounder, N; Prakoshyn, F; Pronko, A; Proudfoot, J; Ptohosh, F; Punzi, G; Pursley, J; Rademackerc, J; Rahaman, A; Ramakrishnan, V; Ranjan, N; Redondo, I; Reisert, B; Rekovic, V; Renton, P B; Rescigno, M; Richter, S; Rimondi, F; Ristori, L; Robson, A; Rodrigo, T; Rogers, E; Rolli, S; Roser, R; Rossi, M; Rossin, R; Roy, P; Ruiz, A; Russ, J; Rusu, V; Saarikko, H; Safonov, A; Sakumoto, W K; Salamanna, G; Salt, O; Santi, L; Sarkar, S; Sartori, L; Sato, K; Savoy-Navarro, A; Scheidle, T; Schlabach, P; Schmidt, E E; Schmidt, M A; Schmidt, M P; Schmitt, M; Schwarz, T; Scodellaro, L; Scott, A L; Scribano, A; Scuri, F; Sedov, A; Seidel, S; Seiya, Y; Semenov, A; Sexton-Kennedy, L; Sfyria, A; Shalhout, S Z; Shapiro, M D; Shears, T G; Shepard, P F; Sherman, D; Shimojiman, M; Shochet, M; Shon, Y; Shreyber, I; Sidoti, A; Siegrist, J; Sinervo, P; Sisakian, A; Slaughter, A J; Slaunwhite, J; Sliwa, K; Smith, J R; Snider, F D; Snihur, R; Söderberg, M; Soha, A; Somalwar, S; Sorin, V; Spalding, J; Spinella, F; Spreitzer, T; Squillacioti, P; Stanitzki, M; Saint-Denis, R; Stelzer, B; Stelzer-Chilton, O; Stentz, D; Strologas, J; Stuart, D; Suh, J S; Sukhanov, A; Sun, H; Suslov, I; Suzuki, T; Taffarde, A; Takashima, R; Takeuchi, Y; Tanaka, R; Tecchio, M; Teng, P K; Terashi, K; Thomg, J; Thompson, A S; Thompson, G A; Thomson, E; Tipton, P; Tiwari, V; Tkaczyk, S; Toback, D; Tokar, S; Tollefson, K; Tomura, T; Tonelli, D; Torre, S; Torretta, D; Tourneur, S; Trischuk, W; Tu, Y; Turini, N; Ukegawa, F; Uozumi, S; Vallecorsa, S; Van Remortel, N; Varganov, A; Vataga, E; Vzquezl, F; Velev, G; Vellidisa, C; Veszpremi, V; Vidal, M; Vidal, R; Vila, I; Vilar, R; Vine, T; Vogel, M; Volobouevq, I; Volpi, G; Würthwein, F; Wagner, P; Wagner, R G; Wagner, R L; Wagner-Kuhr, J; Wagner, W; Wakisaka, T; Wallny, R; Wang, S M; Warburton, A; Waters, D; Weinberger, M; Wester, W C; Whitehouse, B; Whitesone, D; Wicklund, A B; Wicklund, E; Williams, G; Williams, H H; Wilson, P; Winer, B L; Wittichg, P; Wolbers, S; Wolfe, C; Wright, T; Wu, X; Wynne, S M; Yagil, A; Yamamoto, K; Yamaoka, J; Yamashita, T; Yang, C; Yangm, U K; Yang, Y C; Yao, W M; Yeh, G P; Yoh, J; Yorita, K; Yoshida, T; Yu, G B; Yu, I; Yu, S S; Yun, J C; Zanello, L; Zanetti, A; Zaw, I; Zhang, X; Zhengb, Y; Zucchelli, S

    2007-01-01

    We report on the results of a search for standard model Higgs bosons produced in association with W bosons from p-pbar collisions at root s = 1.96 TeV. The search uses a data sample corresponding to approximately 1 fb-1 of integrated luminosity. Events consistent with the W to l-nu and H to b-bbar signature are selected by triggering on a high-pT electron or muon candidate and tagging one or two of the jet candidates as having originated from b quarks. A neural network filter rejects a fraction of tagged charm and light flavor jets, increasing the b-jet purity in the sample and thereby reducing the background to Higgs boson production. We observe no excess l-nu-b-bbar production beyond the background expectation, and we set 95% confidence level upper limits on the production cross section times branching fraction sigma(p-pbar to WH) times Br(H to b-bbar) ranging from 3.9 to 1.3 pb, for specific Higgs boson mass hypotheses in the range 110 to 150 GeV/c2, respectively.

  19. Mastitis Pathogens with High Virulence in a Mouse Model Produce a Distinct Cytokine Profile In Vivo

    Science.gov (United States)

    Johnzon, Carl-Fredrik; Artursson, Karin; Söderlund, Robert; Guss, Bengt; Rönnberg, Elin; Pejler, Gunnar

    2016-01-01

    Mastitis is a serious medical condition of dairy cattle. Here, we evaluated whether the degree of virulence of mastitis pathogens in a mouse model can be linked to the inflammatory response that they provoke. Clinical isolates of Staphylococcus aureus (S. aureus) (strain 556 and 392) and Escherichia coli (E. coli) (676 and 127), and laboratory control strains [8325-4 (S. aureus) and MG1655 (E. coli)], were injected i.p. into mice, followed by the assessment of clinical scores and inflammatory parameters. As judged by clinical scoring, E. coli 127 exhibited the largest degree of virulence among the strains. All bacterial strains induced neutrophil recruitment. However, whereas E. coli 127 induced high peritoneal levels of CXCL1, G-CSF, and CCL2, strikingly lower levels of these were induced by the less virulent bacterial strains. High concentrations of these compounds were also seen in blood samples taken from animals infected with E. coli 127, suggesting systemic inflammation. Moreover, the levels of CXCL1 and G-CSF, both in the peritoneal fluid and in plasma, correlated with clinical score. Together, these findings suggest that highly virulent clinical mastitis isolates produce a distinct cytokine profile that shows a close correlation with the severity of the bacterial infection. PMID:27713743

  20. A REGIONAL ANALYSIS OF THE USE OF TRACTORS ON MODEL FARMS PRODUCING ENERGY CROPS

    Directory of Open Access Journals (Sweden)

    Benedykt Pepliński

    2015-06-01

    Full Text Available The potential area of energy crops in Poland is estimated at 1.0–4.5 million ha. The decrease in the prices of energy reduces the high pressure to cut the costs of biomass production. The aim of this study is an analysis of the use of tractors on model farms producing energy crops, which have different areas, intensity of production and quality of soils from different regions of Poland. The use of tractors increased along with the farm area, the soil quality and production intensity. The use of tractors on the smallest farms is low, so they should buy old tractors. A large share of crops for biogas leads to the situation where it takes 20–30 years of work for tractors to achieve full wear of 12,000 hours on farms with 130 ha of farmland, whereas it takes only 8–14 years on farms with 600 and 1500 ha of farmland. Regional differences in the use of tractors increased along with the farm area from 4.7–5.7% on the smallest farms to 10.1–14.8% on the largest farms.

  1. Search for Standard Model Higgs Bosons Produced in Association with W Bosons

    Science.gov (United States)

    Aaltonen, T.; Adelman, J.; Akimoto, T.; Albrow, M. G.; González, B. Álvarez; Amerio, S.; Amidei, D.; Anastassov, A.; Annovi, A.; Antos, J.; Aoki, M.; Apollinari, G.; Apresyan, A.; Arisawa, T.; Artikov, A.; Ashmanskas, W.; Attal, A.; Aurisano, A.; Azfar, F.; Azzi-Bacchetta, P.; Azzurri, P.; Bacchetta, N.; Badgett, W.; Barbaro-Galtieri, A.; Barnes, V. E.; Barnett, B. A.; Baroiant, S.; Bartsch, V.; Bauer, G.; Beauchemin, P.-H.; Bedeschi, F.; Bednar, P.; Behari, S.; Bellettini, G.; Bellinger, J.; Belloni, A.; Benjamin, D.; Beretvas, A.; Beringer, J.; Berry, T.; Bhatti, A.; Binkley, M.; Bisello, D.; Bizjak, I.; Blair, R. E.; Blocker, C.; Blumenfeld, B.; Bocci, A.; Bodek, A.; Boisvert, V.; Bolla, G.; Bolshov, A.; Bortoletto, D.; Boudreau, J.; Boveia, A.; Brau, B.; Bridgeman, A.; Brigliadori, L.; Bromberg, C.; Brubaker, E.; Budagov, J.; Budd, H. S.; Budd, S.; Burkett, K.; Busetto, G.; Bussey, P.; Buzatu, A.; Byrum, K. L.; Cabrera, S.; Campanelli, M.; Campbell, M.; Canelli, F.; Canepa, A.; Carlsmith, D.; Carosi, R.; Carrillo, S.; Carron, S.; Casal, B.; Casarsa, M.; Castro, A.; Catastini, P.; Cauz, D.; Cavalli-Sforza, M.; Cerri, A.; Cerrito, L.; Chang, S. H.; Chen, Y. C.; Chertok, M.; Chiarelli, G.; Chlachidze, G.; Chlebana, F.; Cho, K.; Chokheli, D.; Chou, J. P.; Choudalakis, G.; Chuang, S. H.; Chung, K.; Chung, W. H.; Chung, Y. S.; Ciobanu, C. I.; Ciocci, M. A.; Clark, A.; Clark, D.; Compostella, G.; Convery, M. E.; Conway, J.; Cooper, B.; Copic, K.; Cordelli, M.; Cortiana, G.; Crescioli, F.; Cuenca Almenar, C.; Cuevas, J.; Culbertson, R.; Cully, J. C.; Dagenhart, D.; Datta, M.; Davies, T.; de Barbaro, P.; de Cecco, S.; Deisher, A.; de Lentdecker, G.; de Lorenzo, G.; Dell'Orso, M.; Demortier, L.; Deng, J.; Deninno, M.; de Pedis, D.; Derwent, P. F.; di Giovanni, G. P.; Dionisi, C.; di Ruzza, B.; Dittmann, J. R.; D'Onofrio, M.; Donati, S.; Dong, P.; Donini, J.; Dorigo, T.; Dube, S.; Efron, J.; Erbacher, R.; Errede, D.; Errede, S.; Eusebi, R.; Fang, H. C.; Farrington, S.; Fedorko, W. T.; Feild, R. G.; Feindt, M.; Fernandez, J. P.; Ferrazza, C.; Field, R.; Flanagan, G.; Forrest, R.; Forrester, S.; Franklin, M.; Freeman, J. C.; Furic, I.; Gallinaro, M.; Galyardt, J.; Garberson, F.; Garcia, J. E.; Garfinkel, A. F.; Gerberich, H.; Gerdes, D.; Giagu, S.; Giakoumopolou, V.; Giannetti, P.; Gibson, K.; Gimmell, J. L.; Ginsburg, C. M.; Giokaris, N.; Giordani, M.; Giromini, P.; Giunta, M.; Glagolev, V.; Glenzinski, D.; Gold, M.; Goldschmidt, N.; Golossanov, A.; Gomez, G.; Gomez-Ceballos, G.; Goncharov, M.; González, O.; Gorelov, I.; Goshaw, A. T.; Goulianos, K.; Gresele, A.; Grinstein, S.; Grosso-Pilcher, C.; Group, R. C.; Grundler, U.; Guimaraes da Costa, J.; Gunay-Unalan, Z.; Haber, C.; Hahn, K.; Hahn, S. R.; Halkiadakis, E.; Hamilton, A.; Han, B.-Y.; Han, J. Y.; Handler, R.; Happacher, F.; Hara, K.; Hare, D.; Hare, M.; Harper, S.; Harr, R. F.; Harris, R. M.; Hartz, M.; Hatakeyama, K.; Hauser, J.; Hays, C.; Heck, M.; Heijboer, A.; Heinemann, B.; Heinrich, J.; Henderson, C.; Herndon, M.; Heuser, J.; Hewamanage, S.; Hidas, D.; Hill, C. S.; Hirschbuehl, D.; Hocker, A.; Hou, S.; Houlden, M.; Hsu, S.-C.; Huffman, B. T.; Hughes, R. E.; Husemann, U.; Huston, J.; Incandela, J.; Introzzi, G.; Iori, M.; Ivanov, A.; Iyutin, B.; James, E.; Jayatilaka, B.; Jeans, D.; Jeon, E. J.; Jindariani, S.; Johnson, W.; Jones, M.; Joo, K. K.; Jun, S. Y.; Jung, J. E.; Junk, T. R.; Kamon, T.; Kar, D.; Karchin, P. E.; Kato, Y.; Kephart, R.; Kerzel, U.; Khotilovich, V.; Kilminster, B.; Kim, D. H.; Kim, H. S.; Kim, J. E.; Kim, M. J.; Kim, S. B.; Kim, S. H.; Kim, Y. K.; Kimura, N.; Kirsch, L.; Klimenko, S.; Klute, M.; Knuteson, B.; Ko, B. R.; Koay, S. A.; Kondo, K.; Kong, D. J.; Konigsberg, J.; Korytov, A.; Kotwal, A. V.; Kraus, J.; Kreps, M.; Kroll, J.; Krumnack, N.; Kruse, M.; Krutelyov, V.; Kubo, T.; Kuhlmann, S. E.; Kuhr, T.; Kulkarni, N. P.; Kusakabe, Y.; Kwang, S.; Laasanen, A. T.; Lai, S.; Lami, S.; Lammel, S.; Lancaster, M.; Lander, R. L.; Lannon, K.; Lath, A.; Latino, G.; Lazzizzera, I.; Lecompte, T.; Lee, J.; Lee, J.; Lee, Y. J.; Lee, S. W.; Lefèvre, R.; Leonardo, N.; Leone, S.; Levy, S.; Lewis, J. D.; Lin, C.; Lin, C. S.; Linacre, J.; Lindgren, M.; Lipeles, E.; Lister, A.; Litvintsev, D. O.; Liu, T.; Lockyer, N. S.; Loginov, A.; Loreti, M.; Lovas, L.; Lu, R.-S.; Lucchesi, D.; Lueck, J.; Luci, C.; Lujan, P.; Lukens, P.; Lungu, G.; Lyons, L.; Lys, J.; Lysak, R.; Lytken, E.; Mack, P.; MacQueen, D.; Madrak, R.; Maeshima, K.; Makhoul, K.; Maki, T.; Maksimovic, P.; Malde, S.; Malik, S.; Manca, G.; Manousakis, A.; Margaroli, F.; Marino, C.; Marino, C. P.; Martin, A.; Martin, M.; Martin, V.; Martínez, M.; Martínez-Ballarín, R.; Maruyama, T.; Mastrandrea, P.; Masubuchi, T.; Mattson, M. E.; Mazzanti, P.; McFarland, K. S.; McIntyre, P.; McNulty, R.; Mehta, A.; Mehtala, P.; Menzemer, S.; Menzione, A.; Merkel, P.; Mesropian, C.; Messina, A.; Miao, T.; Miladinovic, N.; Miles, J.; Miller, R.; Mills, C.; Milnik, M.; Mitra, A.; Mitselmakher, G.; Miyake, H.; Moed, S.; Moggi, N.; Moon, C. S.; Moore, R.; Morello, M.; Movilla Fernandez, P.; Mülmenstädt, J.; Mukherjee, A.; Muller, Th.; Mumford, R.; Murat, P.; Mussini, M.; Nachtman, J.; Nagai, Y.; Nagano, A.; Naganoma, J.; Nakamura, K.; Nakano, I.; Napier, A.; Necula, V.; Neu, C.; Neubauer, M. S.; Nielsen, J.; Nodulman, L.; Norman, M.; Norniella, O.; Nurse, E.; Oh, S. H.; Oh, Y. D.; Oksuzian, I.; Okusawa, T.; Oldeman, R.; Orava, R.; Osterberg, K.; Pagan Griso, S.; Pagliarone, C.; Palencia, E.; Papadimitriou, V.; Papaikonomou, A.; Paramonov, A. A.; Parks, B.; Pashapour, S.; Patrick, J.; Pauletta, G.; Paulini, M.; Paus, C.; Pellett, D. E.; Penzo, A.; Phillips, T. J.; Piacentino, G.; Piedra, J.; Pinera, L.; Pitts, K.; Plager, C.; Pondrom, L.; Portell, X.; Poukhov, O.; Pounder, N.; Prakoshyn, F.; Pronko, A.; Proudfoot, J.; Ptohos, F.; Punzi, G.; Pursley, J.; Rademacker, J.; Rahaman, A.; Ramakrishnan, V.; Ranjan, N.; Redondo, I.; Reisert, B.; Rekovic, V.; Renton, P.; Rescigno, M.; Richter, S.; Rimondi, F.; Ristori, L.; Robson, A.; Rodrigo, T.; Rogers, E.; Rolli, S.; Roser, R.; Rossi, M.; Rossin, R.; Roy, P.; Ruiz, A.; Russ, J.; Rusu, V.; Saarikko, H.; Safonov, A.; Sakumoto, W. K.; Salamanna, G.; Saltó, O.; Santi, L.; Sarkar, S.; Sartori, L.; Sato, K.; Savoy-Navarro, A.; Scheidle, T.; Schlabach, P.; Schmidt, E. E.; Schmidt, M. A.; Schmidt, M. P.; Schmitt, M.; Schwarz, T.; Scodellaro, L.; Scott, A. L.; Scribano, A.; Scuri, F.; Sedov, A.; Seidel, S.; Seiya, Y.; Semenov, A.; Sexton-Kennedy, L.; Sfyria, A.; Shalhout, S. Z.; Shapiro, M. D.; Shears, T.; Shepard, P. F.; Sherman, D.; Shimojima, M.; Shochet, M.; Shon, Y.; Shreyber, I.; Sidoti, A.; Siegrist, J.; Sinervo, P.; Sisakyan, A.; Slaughter, A. J.; Slaunwhite, J.; Sliwa, K.; Smith, J. R.; Snider, F. D.; Snihur, R.; Soderberg, M.; Soha, A.; Somalwar, S.; Sorin, V.; Spalding, J.; Spinella, F.; Spreitzer, T.; Squillacioti, P.; Stanitzki, M.; St. Denis, R.; Stelzer, B.; Stelzer-Chilton, O.; Stentz, D.; Strologas, J.; Stuart, D.; Suh, J. S.; Sukhanov, A.; Sun, H.; Suslov, I.; Suzuki, T.; Taffard, A.; Takashima, R.; Takeuchi, Y.; Tanaka, R.; Tecchio, M.; Teng, P. K.; Terashi, K.; Thom, J.; Thompson, A. S.; Thompson, G. A.; Thomson, E.; Tipton, P.; Tiwari, V.; Tkaczyk, S.; Toback, D.; Tokar, S.; Tollefson, K.; Tomura, T.; Tonelli, D.; Torre, S.; Torretta, D.; Tourneur, S.; Trischuk, W.; Tu, Y.; Turini, N.; Ukegawa, F.; Uozumi, S.; Vallecorsa, S.; van Remortel, N.; Varganov, A.; Vataga, E.; Vázquez, F.; Velev, G.; Vellidis, C.; Veszpremi, V.; Vidal, M.; Vidal, R.; Vila, I.; Vilar, R.; Vine, T.; Vogel, M.; Volobouev, I.; Volpi, G.; Würthwein, F.; Wagner, P.; Wagner, R. G.; Wagner, R. L.; Wagner-Kuhr, J.; Wagner, W.; Wakisaka, T.; Wallny, R.; Wang, S. M.; Warburton, A.; Waters, D.; Weinberger, M.; Wester, W. C., III; Whitehouse, B.; Whiteson, D.; Wicklund, A. B.; Wicklund, E.; Williams, G.; Williams, H. H.; Wilson, P.; Winer, B. L.; Wittich, P.; Wolbers, S.; Wolfe, C.; Wright, T.; Wu, X.; Wynne, S. M.; Yagil, A.; Yamamoto, K.; Yamaoka, J.; Yamashita, T.; Yang, C.; Yang, U. K.; Yang, Y. C.; Yao, W. M.; Yeh, G. P.; Yoh, J.; Yorita, K.; Yoshida, T.; Yu, G. B.; Yu, I.; Yu, S. S.; Yun, J. C.; Zanello, L.; Zanetti, A.; Zaw, I.; Zhang, X.; Zheng, Y.; Zucchelli, S.

    2008-02-01

    We report on the results of a search for standard model Higgs bosons produced in association with W bosons from pp¯ collisions at s=1.96TeV. The search uses a data sample corresponding to approximately 1fb-1 of integrated luminosity. Events consistent with the W→ℓν and H→bb¯ signature are selected by triggering on a high-pT electron or muon candidate and tagging one or two of the jet candidates as having originated from b quarks. A neural network filter rejects a fraction of tagged charm and light-flavor jets, increasing the b-jet purity in the sample. We observe no excess ℓνbb¯ production beyond the background expectation, and we set 95% confidence level upper limits on the production cross section times branching fraction σ(pp¯→WH)Br(H→bb¯) ranging from 3.9 to 1.3 pb, for specific Higgs boson mass hypotheses in the range 110 to 150GeV/c2, respectively.

  2. Search for Standard Model Higgs Bosons Produced in Association with W Bosons

    Energy Technology Data Exchange (ETDEWEB)

    Aaltonen, T.

    2007-10-01

    The authors report on the results of a search for standard model Higgs bosons produced in association with W bosons from p{bar p} collisions at {radical}s = 1.96 TeV. The search uses a data sample corresponding to approximately 1 fb{sup -1} of integrated luminosity. Events consistent with the W {yields} {ell}{nu} and H {yields} b{bar b} signature are selected by triggering on a high-p{sub T} electron or muon candidate and tagging one or two of the jet candidates as having originated from b quarks. A neural network filter rejects a fraction of tagged charm and light flavor jets, increasing the b-jet purity in the sample and thereby reducing the background to Higgs boson production. They observe no excess {ell}{nu}b{bar b} production beyond the background expectation, and they set 95% confidence level upper limits on the production cross section times branching fraction {sigma}(p{bar p} {yields} WH) {center_dot} Br(H {yields} b{bar b}) ranging from 3.9 to 1.3 pb, for specific Higgs boson mass hypotheses in the range 110 to 150 GeV/c{sup 2}, respectively.

  3. Sequence dependence of kinetics and morphology of collagen model peptide self-assembly into higher order structures

    Science.gov (United States)

    Kar, Karunakar; Wang, Yuh-Hwa; Brodsky, Barbara

    2008-01-01

    The process of self-assembly of the triple-helical peptide (Pro-Hyp-Gly)10 into higher order structure resembles the nucleation-growth mechanism of collagen fibril formation in many features, but the irregular morphology of the self-assembled peptide contrasts with the ordered fibers and networks formed by collagen in vivo. The amino acid sequence in the central region of the (Pro-Hyp-Gly)10 peptide was varied and found to affect the kinetics of self-assembly and nature of the higher order structure formed. Single amino acid changes in the central triplet produced irregular higher order structures similar to (Pro-Hyp-Gly)10, but the rate of self-association was markedly delayed by a single change in one Pro to Ala or Leu. The introduction of a Hyp-rich hydrophobic sequence from type IV collagen resulted in a more regular suprastructure of extended fibers that sometimes showed supercoiling and branching features similar to those seen for type IV collagen in the basement membrane network. Several peptides, where central Pro-Hyp sequences were replaced by charged residues or a nine-residue hydrophobic region from type III collagen, lost the ability to self-associate under standard conditions. The inability to self-assemble likely results from loss of imino acids, and lack of an appropriate distribution of hydrophobic/electrostatic residues. The effect of replacement of a single Gly residue was also examined, as a model for collagen diseases such as osteogenesis imperfecta and Alport syndrome. Unexpectedly, the Gly to Ala replacement interfered with self-assembly of (Pro-Hyp-Gly)10, while the peptide with a Gly to Ser substitution self-associated to form a fibrillar structure. PMID:18441232

  4. Molecular spinless energies of the modified Rosen-Morse potential energy model in higher spatial dimensions

    Science.gov (United States)

    Jia, Chun-Sheng; Dai, Jian-Wei; Zhang, Lie-Hui; Liu, Jian-Yi; Zhang, Guang-Dong

    2015-01-01

    We solve the Klein-Gordon equation with the modified Rosen-Morse potential energy model in D spatial dimensions. The bound state energy equation has been obtained by using the supersymmetric WKB approximation approach. We find that the inter-dimensional degeneracy symmetry exists for the molecular system represented by the modified Rosen-Morse potential. For fixed vibrational and rotational quantum numbers, the relativistic energies for the 61Πu state of the 7Li2 molecule and the X3Π state of the SiC radical increase as D increases. We observe that the behavior of the relativistic vibrational energies in higher dimensions remains similar to that of the three-dimensional system.

  5. VALIDATING QUALITY PROCESS MANAGEMENT INSTRUMENT FOR HIGHER EDUCATION USING STRUCTURAL EQUATION MODELLING

    Directory of Open Access Journals (Sweden)

    David Jimoh Kayode

    2016-06-01

    Full Text Available This study attempts to validate process management scale using rigorous validation procedures. An adapted questionnaire comprising 77 items was administered to faculty members in two public universities in Nigeria. The data gathered were analyzed using exploratory factor analysis and confirmatory factor analysis with SPSS 20.0 and SmartPLS 3.1.2 respectively. The findings of this study shows that process management is a third order reflective model with multidimensional constructs. The two dimension of process management administrative process and academic process has four and five dimensions respectively. The process management scale will therefore facilitate the identifications of elements that influence the effectiveness of higher education. The practical implications and methodological limitations are discussed.

  6. MEMFASILITASI HIGHER ORDER THINKING SKILLS DALAM PERKULIAHAN BIOLOGI SEL MELALUI MODEL INTEGRASI ATRIBUT ASESMEN FORMATIF

    Directory of Open Access Journals (Sweden)

    Sigit Saptono

    2017-02-01

    Full Text Available Abstrak ___________________________________________________________________ Higher order thinking skills sangat dibutuhkan untuk memahami permasalahan dan esensi materi perkuliahan Biologi Sel. Studi dengan desain Research and Development ini bertujuan untuk mengembangkan kemampuan penalaran dan berpikir analitik mahasiswa calon guru biologi melalui penerapan model pembelajaran Integrasi Atribut Asesmen Formatif (IAAF. Sejumlah 61 mahasiswa program studi Pendidikan Biologi Universitas Negeri Semarang semester tiga yang sedang menempuh mata kuliah Biologi Sel menjadi subjek penelitian. Kemampuan penalaran dan berpikir analitik mahasiswa diukur melalui tugas individu, tugas kelompok pembuatan peta konsep dan penyusunan laporan reviu artikel, dan 30 item soal berbentuk selected response questions dan constructed response questions tervalidasi. Hasil analisis data menunjukkan bahwa kemampuan penalaran dan berpikir analitik mahasiswa dapat berkembang secara signifikan, meskipun perkembangan kemampuan argumentasi, salah satu kategori kemampuan berpikir analitik, masih perlu perhatian yang cukup serius.   Abstract ___________________________________________________________________ Higher order thinking skills are needed to understand the problem and the essence of the lecture material Biology Sel. Study design Research and Development aims to develop reasoning skills and analytic thinking biology student teachers through the application of learning models Integration Attributes Formative Assessment (IAAF. Some 61 students of Biology Education Semarang State University who is doing his third semester courses Cell Biology is the subject of research. Analytical reasoning and thinking ability of students is measured through individual assignments, group assignments concept map creation and preparation of the Review articles, and 30 items about the shape of the selected response and constructed response questions, validated questions. The result showed

  7. Modeling Approach for Estimating Co-Produced Water Volumes and Saltwater Disposal Volumes in Oklahoma

    Science.gov (United States)

    Murray, K. E.

    2016-12-01

    Management of produced fluids has become an important issue in Oklahoma because large volumes of saltwater are co-produced with oil and gas, and disposed into saltwater disposal wells at high rates. Petroleum production increased from 2009-2015, especially in central and north-central Oklahoma where the Mississippian and Hunton zones were redeveloped using horizontal wells and dewatering techniques that have led to a disproportional increase in produced water volumes. Improved management of co-produced water, including desalination for beneficial reuse and decreased saltwater disposal volumes, is only possible if spatial and temporal trends can be defined and related to the producing zones. It is challenging to quantify the volumes of co-produced water by region or production zone because co-produced water volumes are generally not reported. Therefore, the goal of this research is to estimate co-produced water volumes for 2008-present with an approach that can be replicated as petroleum production shifts to other regions. Oil and gas production rates from subsurface zones were multiplied by ratios of H2O:oil and H2O:gas for the respective zones. Initial H2O:oil and H2O:gas ratios were adjusted/calibrated, by zone, to maximize correlation of county-scale produced H2O estimates versus saltwater disposal volumes from 2013-2015. These calibrated ratios were then used to compute saltwater disposal volumes from 2008-2012 because of apparent data gaps in reported saltwater disposal volumes during that timeframe. This research can be used to identify regions that have the greatest need for produced water treatment systems. The next step in management of produced fluids is to explore optimal energy-efficient strategies that reduce deleterious effects.

  8. A mixed model reduces spurious genetic associations produced by population stratification in genome-wide association studies.

    Science.gov (United States)

    Shin, Jimin; Lee, Chaeyoung

    2015-04-01

    Population stratification can produce spurious genetic associations in genome-wide association studies (GWASs). Mixed model methodology has been regarded useful for correcting population stratification. This study explored statistical power and false discovery rate (FDR) with the data simulated for dichotomous traits. Empirical FDRs and powers were estimated using fixed models with and without genomic control and using mixed models with and without reflecting loci linked to the candidate marker in genetic relationships. Population stratification with admixture degree ranged from 1% to 10% resulted in inflated FDRs from the fixed model analysis without genomic control and decreased power from the fixed model analysis with genomic control (Ppopulation stratification could not change FDR and power estimates from the mixed model analyses (P>0.05). We suggest that the mixed model methodology was useful to reduce spurious genetic associations produced by population stratification in GWAS, even with a high degree of admixture (10%). Copyright © 2015 Elsevier Inc. All rights reserved.

  9. Tests of the higher order turbulence model for atmospheric circulations (HOTMAC) at Deseret Chemical Depot

    Energy Technology Data Exchange (ETDEWEB)

    Costigan, K.R.

    1998-11-01

    Deseret Chemical Depot is one of the US Army`s storage facilities for its stockpile of chemical weapon agents. Congress has directed the Department of Defense to eliminate the aging stockpiles, which have existed since the end of World War II, and the US Army is destroying these lethal chemical munitions. Although the danger is slight, accurate predictions of the wind field in the valley are necessary for dispersion calculations in the event of an accident involving toxic chemicals at the depot. There are several small communities in Rush and Tooele valleys, including the town of Tooele, and Salt Lake City is located 65 km to the Northeast of Deseret Chemical Depot South area, at 1,300 m MSL and beyond the Oquirrh Mountains. The purpose of this report is to carry out three-dimensional numerical simulations of the atmospheric circulations in the region around Deseret Chemical Depot with the Higher Order Turbulence Model for Atmospheric Circulations (HOTMAC) and to evaluate the performance of the model. The code had been modified to assimilate local meteorological observations through the use of Newtonian nudging. The nudging scheme takes advantage of the extensive network of local observations in the valley.

  10. APPLICATION OF ISO 9001 AND EFQM EXCELLENCE MODEL WITHIN HIGHER EDUCATION INSTITUTIONS: PRACTICAL EXPERIENCES ANALYSIS

    Directory of Open Access Journals (Sweden)

    Ramune Kasperaviciute

    2013-06-01

    Full Text Available Purpose – to systemise and analyse practical experiences of the application of the EFQM Excellence Model (EM and ISO 9001 standard within Higher education institutions (HEIs. There is an aim to understand: 1 what are the main motives of the application of the analysed quality management (QM means within academic institutions; 2 what are the most common issues occurring during the implementation; 3 what are the most common benefits. Design/methodology/approach – practical experiences of HEIs from various countries are analysed and the data from 30 case studies (17 case studies focus on experiences applying ISO 9001 standard for quality management system (QMS development and 13 case studies focus on experiences implementing EFQM EM summarized. The sample of the research was formed after review of relevant scientific researches between 1995 and 2013 available in EBSCO, Emerald Management Journal Collection, ProQuest, JSTOR, Sage Publications: Sage Journal Online databases. Selection criteria of case studies was application of ISO 9001 and EFQM EM in HEIs from various countries. Research methods: systematic scientific literature analysis, content analysis. Findings – the research revealed that the main motives of HEIs to apply ISO 9001 and the EFQM EM are related the most common to internal institutional needs, competitiveness in the market and requirements of the stakeholders. 18 fundamental issues of the application of the means were identified which are more often related to institutional problems than to standard/model issues. The implementation of both means within academic institutions conditioned the benefits linked with internal institutional changes. The most significant general benefits are related to the goals of the means and cultural changes of the institution. Research limitations/implications – case studies publicised in English and Lithuanian languages only were analysed in the article. The inclusion of available researches

  11. Application of radiosurgical techniques to produce a primate model of brain lesions

    Directory of Open Access Journals (Sweden)

    Jun eKunimatsu

    2015-04-01

    Full Text Available Behavioral analysis of subjects with discrete brain lesions provides important information about the mechanisms of various brain functions. However, it is generally difficult to experimentally produce discrete lesions in deep brain structures. Here we show that a radiosurgical technique, which is used as an alternative treatment for brain tumors and vascular malformations, is applicable to create non-invasive lesions in experimental animals for the research in systems neuroscience. We delivered highly focused radiation (130–150 Gy at ISO center to the frontal eye field of macaque monkeys using a clinical linear accelerator (LINAC. The effects of irradiation were assessed by analyzing oculomotor performance along with magnetic resonance (MR images before and up to 8 months following irradiation. In parallel with tissue edema indicated by MR images, deficits in saccadic and smooth pursuit eye movements were observed during several days following irradiation. Although initial signs of oculomotor deficits disappeared within a month, damage to the tissue and impaired eye movements gradually developed during the course of the subsequent 6 months. Postmortem histological examinations showed necrosis and hemorrhages within a large area of the white matter and, to a lesser extent, in the adjacent gray matter, which was centered at the irradiated target. These results indicated that the LINAC system was useful for making brain lesions in experimental animals, while the suitable radiation parameters to generate more focused lesions need to be further explored. We propose the use of a radiosurgical technique for establishing animal models of brain lesions, and discuss the possible uses of this technique for functional neurosurgical treatments in humans.

  12. Predictive Models for Identification of Hospitalized Patients Harboring KPC-Producing Klebsiella pneumoniae

    Science.gov (United States)

    Trecarichi, Enrico Maria; Tumietto, Fabio; Del Bono, Valerio; De Rosa, Francesco Giuseppe; Bassetti, Matteo; Losito, Angela Raffaella; Tedeschi, Sara; Saffioti, Carolina; Corcione, Silvia; Giannella, Maddalena; Raffaelli, Francesca; Pagani, Nicole; Bartoletti, Michele; Spanu, Teresa; Marchese, Anna; Cauda, Roberto; Viscoli, Claudio; Viale, Pierluigi

    2014-01-01

    The production of Klebsiella pneumoniae carbapenemases (KPCs) by Enterobacteriaceae has become a significant problem in recent years. To identify factors that could predict isolation of KPC-producing K. pneumoniae (KPCKP) in clinical samples from hospitalized patients, we conducted a retrospective, matched (1:2) case-control study in five large Italian hospitals. The case cohort consisted of adult inpatients whose hospital stay included at least one documented isolation of a KPCKP strain from a clinical specimen. For each case enrolled, we randomly selected two matched controls with no KPCKP-positive cultures of any type during their hospitalization. Matching involved hospital, ward, and month/year of admission, as well as time at risk for KPCKP isolation. A subgroup analysis was also carried out to identify risk factors specifically associated with true KPCKP infection. During the study period, KPCKP was isolated from clinical samples of 657 patients; 426 of these cases appeared to be true infections. Independent predictors of KPCKP isolation were recent admission to an intensive care unit (ICU), indwelling urinary catheter, central venous catheter (CVC), and/or surgical drain, ≥2 recent hospitalizations, hematological cancer, and recent fluoroquinolone and/or carbapenem therapy. A Charlson index of ≥3, indwelling CVC, recent surgery, neutropenia, ≥2 recent hospitalizations, and recent fluoroquinolone and/or carbapenem therapy were independent risk factors for KPCKP infection. Models developed to predict KPCKP isolation and KPCKP infection displayed good predictive power, with the areas under the receiver-operating characteristic curves of 0.82 (95% confidence interval [CI], 0.80 to 0.84) and 0.82 (95% CI, 0.80 to 0.85), respectively. This study provides novel information which might be useful for the clinical management of patients harboring KPCKP and for controlling the spread of this organism. PMID:24733460

  13. MATHEMATICAL MODELING OF MUTUALLY BENEFICIAL RELATIONS BEETWEEN RAW MATERIAL PRODUCERS AND PROCESSORS BASED ON NONLINEAR DEMAND FUNCTION

    Directory of Open Access Journals (Sweden)

    Loyko V. I.

    2015-06-01

    Full Text Available Agricultural producers interested in marketing of raw materials, whereas processing companies are interested in the establishment of raw material zones, providing capacity utilization; therefore, the establishment of sustainable linkages between producers and processors of raw materials is an objective necessity. In the article, with the help of mathematical methods we examine the conditions of mutually beneficial economic relations between agricultural producers and processing enterprises. Mathematical model for estimating the profits of the company is built of the following conditions: producers sell processing plants raw materials, determined by the coefficient of the interest in the partnership at an agreed purchase price, and the remaining raw materials are processed, so they can sell their products independently. Profit of the processing plant is determined by the mathematical model. To describe the nonlinear market-based sales of goods from its retail price we used a hyperbolic demand function

  14. Introducing nonlinear, multivariate 'Predictor Surfaces' for quantitative modeling of chemical systems with higher-order, coupled predictor variables.

    Science.gov (United States)

    Horton, Rebecca B; McConico, Morgan; Landry, Currie; Tran, Tho; Vogt, Frank

    2012-10-09

    Innovations in chemometrics are required for studies of chemical systems which are governed by nonlinear responses to chemical parameters and/or interdependencies (coupling) among these parameters. Conventional and linear multivariate models have limited use for quantitative and qualitative investigations of such systems because they are based on the assumption that the measured data are simple superpositions of several input parameters. 'Predictor Surfaces' were developed for studies of more chemically complex systems such as biological materials in order to ensure accurate quantitative analyses and proper chemical modeling for in-depth studies of such systems. Predictor Surfaces are based on approximating nonlinear multivariate model functions by multivariate Taylor expansions which inherently introduce the required coupled and higher-order predictor variables. As proof-of-principle for the Predictor Surfaces' capabilities, an application from environmental analytical chemistry was chosen. Microalgae cells are known to sensitively adapt to changes in environmental parameters such as pollution and/or nutrient availability and thus have potential as novel in situ sensors for environmental monitoring. These adaptations of the microalgae cells are reflected in their chemical signatures which were then acquired by means of FT-IR spectroscopy. In this study, the concentrations of three nutrients, namely inorganic carbon and two nitrogen containing ions, were chosen. Biological considerations predict that changes in nutrient availability produce a nonlinear response in the cells' biomass composition; it is also known that microalgae need certain nutrient mixes to thrive. The nonlinear Predictor Surfaces were demonstrated to be more accurate in predicting the values of these nutrients' concentrations than principal component regression. For qualitative chemical studies of biological systems, the Predictor Surfaces themselves are a novel tool as they visualize

  15. An Aristotelian Model for Ethical Higher Education Marketing: The Role of Practical Wisdom

    Science.gov (United States)

    Gibbs, Paul

    2011-01-01

    This paper discusses the concerns for a distinct ethics for marketers of higher education. It argues that higher education retains a difference for both product and service and that unfettered marketing can influence and then manipulate the underlying edifying offering.

  16. Resonantly produced 7 keV sterile neutrino dark matter models and the properties of Milky Way satellites.

    Science.gov (United States)

    Abazajian, Kevork N

    2014-04-25

    Sterile neutrinos produced through a resonant Shi-Fuller mechanism are arguably the simplest model for a dark matter interpretation of the origin of the recent unidentified x-ray line seen toward a number of objects harboring dark matter. Here, I calculate the exact parameters required in this mechanism to produce the signal. The suppression of small-scale structure predicted by these models is consistent with Local Group and high-z galaxy count constraints. Very significantly, the parameters necessary in these models to produce the full dark matter density fulfill previously determined requirements to successfully match the Milky Way Galaxy's total satellite abundance, the satellites' radial distribution, and their mass density profile, or the "too-big-to-fail problem." I also discuss how further precision determinations of the detailed properties of the candidate sterile neutrino dark matter can probe the nature of the quark-hadron transition, which takes place during the dark matter production.

  17. PREDICTING E-LEARNING APPLICATION IN AGRICULTURAL HIGHER EDUCATION USING TECHNOLOGY ACCEPTANCE MODEL

    Directory of Open Access Journals (Sweden)

    Masoud REZAEI

    2008-01-01

    Full Text Available E-learning is significant breakthrough in teaching and learning. Internet or web technologies are important because they facilitate and enhance communications among instructors and learners and provide tools to encourage creativity and initiative. If internet-based learning environments are to benefit students, then it is important from the student’s perspective that they are not seen as overly complex and hard to use. The introduction of e-learning may hinder the learning process if the technology is perceived as being complex and not useful to enhanced performance, and thus a distraction to learning. In line with acceptance studies, this research proposed and tested students’ acceptance behavior of agricultural higher education for application of e-learning using technology acceptance model. Results demonstrated that there was positive relationship between students’ intention to use e-learning and its perceived usefulness, internet experience, computer self-efficacy and affect. Instead computer anxiety and age had negative relationship with students’ intention to use e-learning.

  18. Higher harmonic nonlocal polymerization driven diffusion model: generalized nonlinearities and nonlocal responses

    Science.gov (United States)

    Kelly, John V.; O'Brien, Jeff; O'Neill, Feidhlim T.; Gleeson, Michael R.; Sheridan, John T.

    2004-10-01

    Non-local and non-linear models of photopolymer materials, which include diffusion effects, have recently received much attention in the literature. The material response is non-local as it is assumed that monomers are polymerised to form polymer chains and that these chains grow away from a point of initiation. The non-locality is defined in terms of a spatial non-local material response function. The numerical method of solution typically involves retaining either two or four harmonics of the Fourier series of monomer concentration in the calculation. In this paper a general set of equations is derived which allows inclusion of higher number of harmonics for any response function. The numerical convergence for varying number of harmonics retained is investigated with special care being taken to note the effect of the; non-local material variance s, the power law degree k, and the rates of diffusion, D, and polymerisation F0. General non-linear material responses are also included.

  19. Modeling Learners’ Readiness to Adopt Mobile Learning: A Perspective from a GCC Higher Education Institution

    Directory of Open Access Journals (Sweden)

    Mohammad Shorfuzzaman

    2016-01-01

    Full Text Available Mobile learning (M-learning has gained significant popularity in recent past due to the explosion of portable devices and the availability of the Internet. The use of this specific technology in learning and training has enriched the success stories of next generation mobile information systems. While M-learning is being widely used in developed countries such as the USA, South Korea, Japan, UK, Singapore, Taiwan, and European Union, most of the Gulf Cooperation Council (GCC countries are lagging behind and facing diversified challenges in adopting M-learning. Thus, investigating learners’ readiness to adopt M-learning in higher education institution in the context of GCC is the focus of this paper. To this end, we introduce a hypothesized model to investigate learners’ readiness to adopt M-learning. The empirical study is conducted by analyzing data collected from participants from a GCC university using a survey questionnaire with the help of statistical tools. The results of the study will be valuable for policy-makers in designing comprehensive M-learning systems in the context of GCC. The implication of the study results on the next generation mobile information system is also discussed with future research directions.

  20. Childhood craniopharyngioma: greater hypothalamic involvement before surgery is associated with higher homeostasis model insulin resistance index

    Directory of Open Access Journals (Sweden)

    Sainte-Rose Christian

    2009-04-01

    Full Text Available Abstract Background Obesity seems to be linked to the hypothalamic involvement in craniopharyngioma. We evaluated the pre-surgery relationship between the degree of this involvement on magnetic resonance imaging and insulin resistance, as evaluated by the homeostasis model insulin resistance index (HOMA. As insulin-like growth factor 1, leptin, soluble leptin receptor (sOB-R and ghrelin may also be involved, we compared their plasma concentrations and their link to weight change. Methods 27 children with craniopharyngioma were classified as either grade 0 (n = 7, no hypothalamic involvement, grade 1 (n = 8, compression without involvement, or grade 2 (n = 12, severe involvement. Results Despite having similar body mass indexes (BMI, the grade 2 patients had higher glucose, insulin and HOMA before surgery than the grade 0 (P = 0.02, The data for the whole population before and 6–18 months after surgery showed increases in BMI (P Conclusion The hypothalamic involvement by the craniopharyngioma before surgery seems to determine the degree of insulin resistance, regardless of the BMI. The pre-surgery HOMA values were correlated with the post-surgery weight gain. This suggests that obesity should be prevented by reducing inn secretion in those cases with hypothalamic involvement.

  1. Investigating polycyclic aromatic hydrocarbons profiles in higher plants using statistical models.

    Science.gov (United States)

    Sojinu, O Samuel; Sonibare, O Oluwadayo; Gayawan, Ezra

    2013-01-01

    Thirty-six higher plants sampled from Olomoro, Irri, Uzere, and Oginni exploration sites in the Niger Delta region of Nigeria were subjected to GC/MS analysis to assess the occurrence, distribution and profiles of polycyclic aromatic hydrocarbons (PAHs) contained in them. The sigma28PAHs ranged from 335 to 3094 ng/g. The results of the nonparametric regression models showed that PAHs concentration in a plant cannot be used in isolation to deduce the total PAHs concentration in soils hosting the plant since PAHs concentration in a plant is influenced by the presence (or absence) of other plants in that location. A combination of Factor analysis (FA) and principal component analysis (PCA) were used to recognize PAHs concentration patterns among the plants in the studied locations and individual PAHs compounds. Woody annuals and perennial plants formed similar patterns in Oginni and Irri locations. Three main clusters were formed by all the compounds with naphthalene and 2-methylnaphthalene standing as outliers in all the four locations.

  2. Molecular modeling assisted hapten design to produce broad selectivity antibodies for fluoroquinolone antibiotics.

    Science.gov (United States)

    Pinacho, Daniel G; Sánchez-Baeza, Francisco; Marco, M-Pilar

    2012-05-15

    Antibodies with a wide recognition profile of fluoroquinolone antibiotics have been produced based on chemical criteria, theoretical studies, and molecular modeling assisted hapten design. The immunizing hapten preserves the most important and characteristic epitopes of this antibiotic family. The studies have taken into consideration the zwitterionic character of most of the fluoroquinolones and the relative concentration of the different species in equilibrium at physiologic pH. The hapten is prepared in the form of a stable prehapten through a 5 step synthetic pathway. Immediately before conjugation, the immunizing hapten is obtained by removing the diphenylmethane protecting group. The specificity of the antibodies obtained is directed toward the common area defined by the fluorine atom at position 6 and the β-ketoacid moiety. The ELISA developed is able to recognize with very good detectability important fluoroquinolones used in the veterinary field such as ciprofloxacin (CPFX, IC(50), 0.35 μg L(-1)), enrofloxacin (ERFX, IC(50), 0.65 μg L(-1)), danofloxacin (DNFX, IC(50), 7.31 μg L(-1)), difloxacin (DFX, IC(50), 0.91 μg L(-1)), sarafloxacin (SRFX, IC(50), 0.96 μg L(-1)), norfloxacin (NRFX, IC(50), 0.78 μg L(-1)), ofloxacin (OFX, IC(50), 1.84 μg L(-1)), flumequine (Flume, IC(50), 3.91 μ gL(-1)), marbofloxacin (MBFX, IC(50), 4.30 μ gL(-1)), and oxolinic acid (OXO, IC(50), 23.53 μg L(-1)). The results presented here demonstrate that the antibody affinity is strongly affected by the presence of divalent cations, owing to their complexation with the fluoroquinolone molecules. Moreover, the outcome from the effect of the pH on the immunochemical assays suggests that the selectivity could be modulated with the pH due to the zwitterionic character of the fluoroquinolones and as a function of their different pK(a) values.

  3. Experimental Model of Cerebral Hypoperfusion Produced Memory-learning Deficits, and Modifications in Gene Expression

    Directory of Open Access Journals (Sweden)

    Rilda LEÓN

    2014-05-01

    Full Text Available Cerebral ischemia is a major cause of death, for this reason animal models of cerebral ischemia are widely used to study both the pathophysiology of ischemic phenomenon and the evaluation of possible therapeutic agents with protective or regenerative properties. The objectives of this study were to examine the presence of neuronal damage in different brain areas following the ischemic event, and assess consequences of such activities on the processes of memory and learning. The study group included an experimental group ischemic animals (30 rats with permanent bilateral occlusion of the carotids, and a control group. Was evaluated gene expression and inflammatory ischemic by qPCR techniques 24h post injury, brain tissue morphology in areas of cortex, striatum and hippocampus seven days post injury and processes of memory and learning, 12 days post injury. The morphological studies showed that the procedure induces death of cell populations in cortex, striatum and hippocampus, ischemia modified gfap gene expression and ho, il-6, il-17 and ifn-γ, which can be used as a marker of early ischemic process. Additionally, the ischemic injury caused spatial memory decline. This characterization gives us an experimental model to develop future studies on the pathophysiology of ischemic events and assessing therapeutic strategies.MODELO EXPERIMENTAL DE HIPOPERFUSIÓN CEREBRAL PRODUCE DÉFICIT DE LA MEMORIA Y APRENDIZAJE Y MODIFICACIONES EN LA EXPRESIÓN DE GENES.A escala mundial, la isquemia cerebral constituye una de las principales causas de muerte, por lo que los modelos animales de isquemia cerebral son extensamente usados tanto en el estudio de la pato-fisiología del fenómeno isquémico; como en la evaluación de agentes terapéuticos con posible efecto protector o regenerador.  Los objetivos de este estudio fueron examinar la presencia de daño neuronal en diferentes áreas cerebrales como consecuencia del evento isquémico; así como evaluar

  4. Characterisation of liquid-liquid interfaces related to offshore produced water treatment - interfacial activity of model Components

    OpenAIRE

    Olhaye, Omar

    2013-01-01

    Produced water is one of the biggest environmental challenges in gas and crude oil production, and the stability of oil in water emulsions makes separation during treatments difficult.The objective of this work is to find out how interfacial active compounds contribute to the stability of oil/water emulsions. A model naphthenic acid dissolved in model oil was used together with a synthetic aqueous brine of different pH values in order to mimic produced water conditions. The experiment was con...

  5. Candidate main-field models for producing the 9th generation IGRF

    Science.gov (United States)

    Mandea, Mioara

    2005-12-01

    This paper presents the various candidate models used in deriving the 9th generation IGRF. Based on notes submitted to the IAGA working group V-MOD with the Gauss coefficients, a brief description of the data used and the method of modelling for each of the candidate models is given. The six candidate models for epoch 1995.0 and the five for epoch 2000.0 are presented. Improvements gained by the new models are also discussed.

  6. Disrupting and Democratising Higher Education Provision or Entrenching Academic Elitism: Towards a Model of MOOCs Adoption at African Universities

    Science.gov (United States)

    Rambe, Patient; Moeti, Mamello

    2017-01-01

    Challenges of broadening access, escalating cost, maintaining desirable quality and enhancing meaningful learning experiences in African higher education (HE) have spurred debates on how to restructure higher education delivery to meet the diverse needs of heterogeneous learners and adapt pedagogical models to the educational realities of…

  7. A Critical Review of the Model Minority Myth in Selected Literature on Asian Americans and Pacific Islanders in Higher Education

    Science.gov (United States)

    Poon, OiYan; Squire, Dian; Kodama, Corinne; Byrd, Ajani; Chan, Jason; Manzano, Lester; Furr, Sara; Bishundat, Devita

    2016-01-01

    This article presents a critical review of 112 works of research on Asian Americans and Pacific Islanders (AAPIs) in higher education. It focuses on ways previous scholarship framed AAPIs in higher education, and specifically on how those works engaged in a sustained project of countering the model minority myth (MMM). Many publications on AAPIs…

  8. Application of Strategic Institutional-Information Technology Alignment Model in Four-Year Institutions of Higher Education

    Science.gov (United States)

    Lach-Smith, Barbara

    2010-01-01

    This study examined an existing corporate model of business-information technology alignment for application in higher education and tested the findings by surveying executive and technology leaders in higher education. The purpose of this study was to gain a better understanding of the factors that impact alignment between institutional strategic…

  9. A Prenatal Multiple Micronutrient Supplement Produces Higher Maternal Vitamin B-12 Concentrations and Similar Folate, Ferritin, and Zinc Concentrations as the Standard 60-mg Iron Plus 400-μg Folic Acid Supplement in Rural Bangladeshi Women.

    Science.gov (United States)

    Ziaei, Shirin; Rahman, Anisur; Raqib, Rubhana; Lönnerdal, Bo; Ekström, Eva-Charlotte

    2016-12-01

    The effects of prenatal food and micronutrient supplementation on maternal micronutrient status are not well known. We compared the efficacy and effectiveness of 3 different micronutrient supplements on maternal micronutrient status when combined with food supplementation. In the MINIMat (Maternal and Infant Nutrition Intervention, Matlab) trial in Bangladesh, 4436 pregnant women were randomly assigned to daily intake of 3 types of micronutrient capsules: 30 mg Fe and 400 μg folic acid (Fe30F), 60 mg Fe and 400 μg folic acid (Fe60F), or multiple micronutrient supplements (MMNs) combined with early (week 9 of pregnancy) or usual (week 20 of pregnancy) food supplementation in a 2 by 3 factorial design. Plasma concentrations of vitamin B-12, folate, ferritin, and zinc were analyzed before the start of micronutrient supplementation (week 14) and at week 30 of pregnancy in 641 randomly selected women. An electronic monitoring device was used to measure the number of capsules taken. The effectiveness of food and micronutrient regimens as well as efficacy per capsule in maternal micronutrient status were analyzed by ANOVA and general linear models. At week 30 of pregnancy, women in the MMN group had higher geometric mean concentrations of vitamin B-12 than women in the Fe60F group (119 compared with 101 pmol/L, respectively); no other differences in effectiveness of micronutrient and food regimens were observed. A dose-response relation between the number of capsules taken and concentrations of folate and ferritin was observed for all micronutrient supplements. Fe30F had lower efficacy per capsule in increasing ferritin concentrations within the first tertile of capsule intake than did Fe60F and MMNs. Because ferritin reached a plateau for all types of micronutrient supplements, there was no difference between the regimens in their effectiveness. Compared with Fe60F, MMNs produced higher maternal vitamin B-12 and similar ferritin and folate concentrations in Bangladeshi

  10. A Prenatal Multiple Micronutrient Supplement Produces Higher Maternal Vitamin B-12 Concentrations and Similar Folate, Ferritin, and Zinc Concentrations as the Standard 60-mg Iron Plus 400-μg Folic Acid Supplement in Rural Bangladeshi Women12

    Science.gov (United States)

    Rahman, Anisur; Raqib, Rubhana; Lönnerdal, Bo; Ekström, Eva-Charlotte

    2016-01-01

    Background: The effects of prenatal food and micronutrient supplementation on maternal micronutrient status are not well known. Objective: We compared the efficacy and effectiveness of 3 different micronutrient supplements on maternal micronutrient status when combined with food supplementation. Methods: In the MINIMat (Maternal and Infant Nutrition Intervention, Matlab) trial in Bangladesh, 4436 pregnant women were randomly assigned to daily intake of 3 types of micronutrient capsules: 30 mg Fe and 400 μg folic acid (Fe30F), 60 mg Fe and 400 μg folic acid (Fe60F), or multiple micronutrient supplements (MMNs) combined with early (week 9 of pregnancy) or usual (week 20 of pregnancy) food supplementation in a 2 by 3 factorial design. Plasma concentrations of vitamin B-12, folate, ferritin, and zinc were analyzed before the start of micronutrient supplementation (week 14) and at week 30 of pregnancy in 641 randomly selected women. An electronic monitoring device was used to measure the number of capsules taken. The effectiveness of food and micronutrient regimens as well as efficacy per capsule in maternal micronutrient status were analyzed by ANOVA and general linear models. Results: At week 30 of pregnancy, women in the MMN group had higher geometric mean concentrations of vitamin B-12 than women in the Fe60F group (119 compared with 101 pmol/L, respectively); no other differences in effectiveness of micronutrient and food regimens were observed. A dose-response relation between the number of capsules taken and concentrations of folate and ferritin was observed for all micronutrient supplements. Fe30F had lower efficacy per capsule in increasing ferritin concentrations within the first tertile of capsule intake than did Fe60F and MMNs. Because ferritin reached a plateau for all types of micronutrient supplements, there was no difference between the regimens in their effectiveness. Conclusion: Compared with Fe60F, MMNs produced higher maternal vitamin B-12 and

  11. Validation of a Previously Developed Geospatial Model That Predicts the Prevalence of Listeria monocytogenes in New York State Produce Fields

    Science.gov (United States)

    Weller, Daniel; Shiwakoti, Suvash; Bergholz, Peter; Grohn, Yrjo; Wiedmann, Martin

    2015-01-01

    Technological advancements, particularly in the field of geographic information systems (GIS), have made it possible to predict the likelihood of foodborne pathogen contamination in produce production environments using geospatial models. Yet, few studies have examined the validity and robustness of such models. This study was performed to test and refine the rules associated with a previously developed geospatial model that predicts the prevalence of Listeria monocytogenes in produce farms in New York State (NYS). Produce fields for each of four enrolled produce farms were categorized into areas of high or low predicted L. monocytogenes prevalence using rules based on a field's available water storage (AWS) and its proximity to water, impervious cover, and pastures. Drag swabs (n = 1,056) were collected from plots assigned to each risk category. Logistic regression, which tested the ability of each rule to accurately predict the prevalence of L. monocytogenes, validated the rules based on water and pasture. Samples collected near water (odds ratio [OR], 3.0) and pasture (OR, 2.9) showed a significantly increased likelihood of L. monocytogenes isolation compared to that for samples collected far from water and pasture. Generalized linear mixed models identified additional land cover factors associated with an increased likelihood of L. monocytogenes isolation, such as proximity to wetlands. These findings validated a subset of previously developed rules that predict L. monocytogenes prevalence in produce production environments. This suggests that GIS and geospatial models can be used to accurately predict L. monocytogenes prevalence on farms and can be used prospectively to minimize the risk of preharvest contamination of produce. PMID:26590280

  12. An Examination of Higher-Order Treatments of Boundary Conditions in Split-Step Fourier Parabolic Equation Models

    Science.gov (United States)

    2015-06-01

    HIGHER-ORDER TREATMENTS OF BOUNDARY CONDITIONS IN SPLIT-STEP FOURIER PARABOLIC EQUATION MODELS by Savas Erdim June 2015 Thesis Advisor...CONDITIONS IN SPLIT-STEP FOURIER PARABOLIC EQUATION MODELS 5. FUNDING NUMBERS 6. AUTHOR(S) Savas Erdim 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES... Parabolic equation models solved using the split-step Fourier (SSF) algorithm, such as the Monterey Miami Parabolic Equation model, are commonly used

  13. Managing Higher Education in a Climate of Contraction: A Conceptual Model.

    Science.gov (United States)

    Doyle, K. J.

    1980-01-01

    Five categories of opportunity for managing institutions successfully in no-growth periods include: producing new or different products, improving productivity with new production methods, opening new markets, locating new sources of support, and restructuring activities. (MSE)

  14. On (Un)Broken Higher-Spin Symmetry in Vector Models

    Science.gov (United States)

    Skvortsov, E. D.

    The simplest consequences of exact and broken higher-spin symmetry are studied. The one-loop anomalous dimensions of higher-spin currents are determined from the multiplet recombination in the spirit of the modern bootstrap programme: the Wilson-Fisher CFT is studied both in the 4-ɛ-expansion and in the large-N. The bulk implications are briefly addressed: part of the higher-spin theory cubic action is reconstructed; one-loop corrections to the AdS masses of higher-spin fields are discussed.

  15. CFD modeling to improve safe and efficient distribution of chlorine dioxide gas for packaging fresh produce

    Science.gov (United States)

    The efficiency of the packaging system in inactivating food borne pathogens and prolonging the shelf life of fresh-cut produce is influenced by the design of the package apart from material and atmospheric conditions. Three different designs were considered to determine a specific package design ens...

  16. A novel IL-10-producing innate lymphoid cells (ILC10) in a contact hypersensitivity mouse model

    Science.gov (United States)

    Kim, Hyuk Soon; Jang, Jong-Hwa; Lee, Min Bum; Jung, In Duk; Park, Yeong-Min; Kim, Young Mi; Choi, Wahn Soo

    2016-01-01

    The immunoregulatory cytokine Interleukin 10 (IL-10) protein is produced by various cells during the course of inflammatory disorders. Mainly, it downregulates pro-inflammatory cytokines, antigen presentation, and helper T cell activation. In this study, we show that the ratio of IL-10-producing cells was significantly increased in lineage negative (i.e., not T, B, or leukocyte cell lineages) cells than in lineage positive cells in lymphoid and peripheral tissues. We further observed that IL-10-producing innate lymphoid cells (ILCs), here called firstly ILC10, were increased in number in oxazolone-induced contact hypersensitivity (CHS) mice. In detail, IL-10-producing lineage negative cells were elevated in the axillary, inguinal lymph node, and ear tissues of CHS mice. Notably, the cells expressed classical ILC marker proteins such as CD45, CD127, and Sca-1. Altogether, our findings suggest for the first time that ILC10s are present in various physiological settings and could be involved in numerous immune responses as regulatory cells. [BMB Reports 2016; 49(5): 293-296] PMID:26949018

  17. A mathematical model for surface roughness of fluidic channels produced by grinding aided electrochemical discharge machining (G-ECDM

    Directory of Open Access Journals (Sweden)

    Ladeesh V. G.

    2017-01-01

    Full Text Available Grinding aided electrochemical discharge machining is a hybrid technique, which combines the grinding action of an abrasive tool and thermal effects of electrochemical discharges to remove material from the workpiece for producing complex contours. The present study focuses on developing fluidic channels on borosilicate glass using G-ECDM and attempts to develop a mathematical model for surface roughness of the machined channel. Preliminary experiments are conducted to study the effect of machining parameters on surface roughness. Voltage, duty factor, frequency and tool feed rate are identified as the significant factors for controlling surface roughness of the channels produced by G-ECDM. A mathematical model was developed for surface roughness by considering the grinding action and thermal effects of electrochemical discharges in material removal. Experiments are conducted to validate the model and the results obtained are in good agreement with that predicted by the model.

  18. Interpretation of cloud-climate feedback as produced by 14 atmospheric general circulation models

    Science.gov (United States)

    Cess, R. D.; Potter, G. L.; Ghan, S. J.; Blanchet, J. P.; Boer, G. J.

    1989-01-01

    Understanding the cause of differences among general circulation model projections of carbon dioxide-induced climatic change is a necessary step toward improving the models. An intercomparison of 14 atmospheric general circulation models, for which sea surface temperature perturbations were used as a surrogate climate change, showed that there was a roughly threefold variation in global climate sensitivity. Most of this variation is attributable to differences in the models' depictions of cloud-climate feedback, a result that emphasizes the need for improvements in the treatment of clouds in these models if they are ultimately to be used as climatic predictors.

  19. Extension and Higher Education Service-Learning: Toward a Community Development Service-Learning Model

    Science.gov (United States)

    Stoecker, Randy

    2014-01-01

    This article explores how on-the-ground Extension educators interface with higher education service-learning. Most service-learning in Extension has focused on precollege youth and 4-H. When we look at higher education service-learning and Extension in Wisconsin, we see that there is not as much connection as might be expected. County-based…

  20. Open-Source Learning Management Systems: A Predictive Model for Higher Education

    Science.gov (United States)

    van Rooij, S. Williams

    2012-01-01

    The present study investigated the role of pedagogical, technical, and institutional profile factors in an institution of higher education's decision to select an open-source learning management system (LMS). Drawing on the results of previous research that measured patterns of deployment of open-source software (OSS) in US higher education and…

  1. Open-Source Learning Management Systems: A Predictive Model for Higher Education

    Science.gov (United States)

    van Rooij, S. Williams

    2012-01-01

    The present study investigated the role of pedagogical, technical, and institutional profile factors in an institution of higher education's decision to select an open-source learning management system (LMS). Drawing on the results of previous research that measured patterns of deployment of open-source software (OSS) in US higher education and…

  2. MODELING OF QUALITY IMPROVEMENT FACULTY MEMBERS IN EDUCATIONAL ORGANIZATIONS HIGHER EDUCATION

    Directory of Open Access Journals (Sweden)

    N. V. Sergeeva

    2013-01-01

    Full Text Available The transition to a two-tier system of education, the introduction of the federal state educational standards of higher education, the requirements of the single European educational space are fundamentally changing the role of faculty in the professional educational organizations of higher education as a simple translator subject knowledge.

  3. Benchmarking in European Higher Education: A Step beyond Current Quality Models

    Science.gov (United States)

    Burquel, Nadine; van Vught, Frans

    2010-01-01

    This paper presents the findings of a two-year EU-funded project (DG Education and Culture) "Benchmarking in European Higher Education", carried out from 2006 to 2008 by a consortium led by the European Centre for Strategic Management of Universities (ESMU), with the Centre for Higher Education Development, UNESCO-CEPES, and the…

  4. A nucleation and growth model of silicon nanoparticles produced by pulsed laser deposition via Monte Carlo simulation

    Science.gov (United States)

    Wang, Yinglong; Qin, Aili; Chu, Lizhi; Deng, Zechao; Ding, Xuecheng; Guan, Li

    2017-02-01

    We simulated the nucleation and growth of Si nanoparticles produced by pulse laser deposition using Monte Carlo method at the molecular (microscopic) level. In the model, the mechanism and thermodynamic conditions of nucleation and growth of Si nanoparticles were described. In a real physical scale of target-substrate configuration, the model was used to analyze the average size distribution of Si nanoparticles in argon ambient gas and the calculated results are in agreement with the experimental results.

  5. A minimal set of invariants as a systematic approach to higher order gravity models: Physical and Cosmological Constraints

    CERN Document Server

    Moldenhauer, Jacob

    2009-01-01

    We compare higher order gravity models to observational constraints from magnitude-redshift supernova data, distance to the last scattering surface of the CMB, and Baryon Acoustic Oscillations. We follow a recently proposed systematic approach to higher order gravity models based on minimal sets of curvature invariants, and select models that pass some physical acceptability conditions (free of ghost instabilities, real and positive propagation speeds, and free of separatrices). Models that satisfy these physical and observational constraints are found in this analysis and do provide fits to the data that are very close to those of the LCDM concordance model. However, we find that the limitation of the models considered here comes from the presence of superluminal mode propagations for the constrained parameter space of the models.

  6. Cross sections and modelling results for TGF- and positron spectrum produced by a negative stepped lightning leader

    NARCIS (Netherlands)

    Köhn, C.; Ebert, U.

    2012-01-01

    We model the energy resolved angular distribution of TGFs and of positrons produced by a negative lightning leader stepping upwards in a thundercloud. First we present our new results for doubly differential cross sections for Bremsstrahlung and pair production based on the triply differential cross

  7. Error-analysis and comparison to analytical models of numerical waveforms produced by the NRAR Collaboration

    CERN Document Server

    Hinder, Ian; Boyle, Michael; Etienne, Zachariah B; Healy, James; Johnson-McDaniel, Nathan K; Nagar, Alessandro; Nakano, Hiroyuki; Pan, Yi; Pfeiffer, Harald P; Pürrer, Michael; Reisswig, Christian; Scheel, Mark A; Sperhake, Ulrich; Szilágyi, Bela; Tichy, Wolfgang; Wardell, Barry; Zenginoglu, Anıl; Alic, Daniela; Bernuzzi, Sebastiano; Bode, Tanja; Brügmann, Bernd; Buchman, Luisa T; Campanelli, Manuela; Chu, Tony; Damour, Thibault; Grigsby, Jason D; Hannam, Mark; Haas, Roland; Hemberger, Daniel A; Husa, Sascha; Kidder, Lawrence E; Laguna, Pablo; London, Lionel; Lovelace, Geoffrey; Lousto, Carlos O; Marronetti, Pedro; Matzner, Richard A; Mösta, Philipp; Mroué, Abdul; Müller, Doreen; Mundim, Bruno C; Nerozzi, Andrea; Paschalidis, Vasileios; Pollney, Denis; Reifenberger, George; Rezzolla, Luciano; Shapiro, Stuart L; Shoemaker, Deirdre; Taracchini, Andrea; Taylor, Nicholas W; Teukolsky, Saul A; Thierfelder, Marcus; Witek, Helvi; Zlochower, Yosef

    2014-01-01

    The Numerical-Relativity-Analytical-Relativity (NRAR) collaboration is a joint effort between members of the numerical relativity, analytical relativity and gravitational-wave data analysis communities. The goal of the NRAR collaboration is to produce numerical-relativity simulations of compact binaries and use them to develop accurate analytical templates for the LIGO/Virgo Collaboration to use in detecting gravitational-wave signals and extracting astrophysical information from them. We describe the results of the first stage of the NRAR project, which focused on producing an initial set of numerical waveforms from binary black holes with moderate mass ratios and spins, as well as one non-spinning binary configuration which has a mass ratio of 10. All of the numerical waveforms are analysed in a uniform and consistent manner, with numerical errors evaluated using an analysis code created by members of the NRAR collaboration. We compare previously-calibrated, non-precessing analytical waveforms, notably the ...

  8. SWIFT-Tyre: an accurate tyre model for ride and handling studies also at higher frequencies and short road wavelengths

    NARCIS (Netherlands)

    Oosten, J.J.M. van; Pacejka, H.B.

    2000-01-01

    As is well known, Magic Formula tyre modelling (MF-Tyre is a part of ADAMS/Tire) allows an accurate and efficient description of tyre-road interaction forces required for any usual vehicle handling simulation. When it comes to modelling of tyre behaviour at higher frequencies and short road obstacle

  9. SWIFT-Tyre: an accurate tyre model for ride and handling studies also at higher frequencies and short road wavelengths

    NARCIS (Netherlands)

    Oosten, J.J.M. van; Pacejka, H.B.

    2000-01-01

    As is well known, Magic Formula tyre modelling (MF-Tyre is a part of ADAMS/Tire) allows an accurate and efficient description of tyre-road interaction forces required for any usual vehicle handling simulation. When it comes to modelling of tyre behaviour at higher frequencies and short road obstacle

  10. The Internationalisation Cube. A Tentative Model for the Study of Organisational Designs and the Results of Internationalisation in Higher Education.

    Science.gov (United States)

    van Dijk, Hans; Meijer, Kees

    1997-01-01

    Based on results of a Dutch study concerning internationalization of higher education, a model for analyzing the internal institutional process of decision making for, organization of, and implementation of international activities is described. The model positions institutions according to three dimensions: policy (importance attached to…

  11. Applying the Many-Facet Rasch Model to Evaluate PowerPoint Presentation Performance in Higher Education

    Science.gov (United States)

    Basturk, Ramazan

    2008-01-01

    This study investigated the usefulness of the many-facet Rasch model (MFRM) in evaluating the quality of performance related to PowerPoint presentations in higher education. The Rasch Model utilizes item response theory stating that the probability of a correct response to a test item/task depends largely on a single parameter, the ability of the…

  12. An experimental model of tool mark striations in soft tissues produced by serrated blades.

    Science.gov (United States)

    Pounder, Derrick J; Cormack, Lesley

    2011-03-01

    Stab wounds produced by serrated blades are generally indistinguishable from stab wounds produced by non-serrated blades, except when visible tool mark striations are left on severed cartilage. We explored the possibility that similar striations may be produced on the soft tissues of internal organs. Loin of beef, bovine kidney, and pig heart, liver, and aorta were each stabbed 20 times with a coarsely serrated blade. The walls of the stab tracks were exposed and documented by photography, cast with dental impression material, and the casts photographed. Striations were identified in all of the tissues in every stabbing, but their consistency and quality varied between tissues. Striations were most easily seen in liver, heart, and aorta. Tool mark striations in soft tissues other than cartilage have not been described in homicidal stabbings, likely because they have not been sought. We suggest that the walls of stab wound tracks should be exposed, and tissue striations should be sought as a means of identifying the weapon as having a serrated blade.

  13. Supernova, baryon acoustic oscillations, and CMB surface distance constraints on f(G) higher order gravity models

    CERN Document Server

    Moldenhauer, Jacob; Thompson, John; Easson, Damien A

    2010-01-01

    We consider recently proposed higher order gravity models where the action is built from the Einstein-Hilbert action plus a function f(G) of the Gauss-Bonnet invariant. The models were previously shown to pass physical acceptability conditions as well as solar system tests. In this paper, we compare the models to combined data sets of supernovae, baryon acoustic oscillations, and constraints from the CMB surface of last scattering. We find that the models provide fits to the data that are close to those of the LCDM concordance model. The results provide a pool of higher order gravity models that pass these tests and need to be compared to constraints from large scale structure and full CMB analysis.

  14. ACADEMIC DISHONESTY IN DISTANCE HIGHER EDUCATION: Challenges and Models for Moral Education in the Digital Era

    OpenAIRE

    Mohammad Imam FARISI

    2013-01-01

    Today, in the era of open access to digital-based information and communication, one of the biggest challenges in higher education to realize moral education and to build academic culture and integrity is the emergence of academic dishonesty behaviors among academic members. The paper describes academic dishonesty behaviors in Distance Higher Education (DHE) institutions within the context of moral education in the digital era. The paper reviews the results of the research on academic dishone...

  15. Triple point in the $O(2)$ ghost model with higher-order gradient term

    CERN Document Server

    Péli, Zoltán; Sailer, Kornél

    2016-01-01

    The phase structure and the infrared behaviour of the Euclidean 3-dimensional $O(2)$ symmetric ghost scalar field $\\phi$ has been investigated in Wegner and Houghton's renormalization group framework, including higher-derivatives in the kinetic term. It is pointed out that higher-derivative coupling provides three phases and leads to a triple point in that RG scheme. The types of the phase transitions have also been identified.

  16. The European University System as a Possible Model for Higher Education in Latin America

    Directory of Open Access Journals (Sweden)

    Antonio Fraile Aranda

    2006-05-01

    Full Text Available In recent years, the European Union has been developing the European Higher Education Area, with the objective of coordinating and homogenizing the policies that regulate the creation and organization of credits and degrees in higher education. In this communication the new proposals for the renovation of the European university are presented for the purpose of analyzing them from a Latin American perspective.

  17. Triple point in the O (2 ) ghost model with higher-order gradient term

    Science.gov (United States)

    Péli, Z.; Nagy, S.; Sailer, K.

    2016-09-01

    The phase structure and the infrared behavior of the Euclidean three-dimensional O (2 ) symmetric ghost scalar field ϕ has been investigated in Wegner and Houghton's renormalization group framework, including higher derivatives in the kinetic term. It is pointed out that higher-derivative coupling provides three phases and leads to a triple point in that RG scheme. The types of the phase transitions have also been identified.

  18. Systematic comparison of the behaviors produced by computational models of epileptic neocortex.

    Energy Technology Data Exchange (ETDEWEB)

    Warlaumont, A. S.; Lee, H. C.; Benayoun, M.; Stevens, R. L.; Hereld, M. (CLS-CI); ( MCS); (Univ. of Chicago); (Univ. of Memphis)

    2010-12-01

    Two existing models of brain dynamics in epilepsy, one detailed (i.e., realistic) and one abstract (i.e., simplified) are compared in terms of behavioral range and match to in vitro mouse recordings. A new method is introduced for comparing across computational models that may have very different forms. First, high-level metrics were extracted from model and in vitro output time series. A principal components analysis was then performed over these metrics to obtain a reduced set of derived features. These features define a low-dimensional behavior space in which quantitative measures of behavioral range and degree of match to real data can be obtained. The detailed and abstract models and the mouse recordings overlapped considerably in behavior space. Both the range of behaviors and similarity to mouse data were similar between the detailed and abstract models. When no high-level metrics were used and principal components analysis was computed over raw time series, the models overlapped minimally with the mouse recordings. The method introduced here is suitable for comparing across different kinds of model data and across real brain recordings. It appears that, despite differences in form and computational expense, detailed and abstract models do not necessarily differ in their behaviors.

  19. A Model of E-Learning Uptake and Continued Use in Higher Education Institutions

    Science.gov (United States)

    Pinpathomrat, Nakarin; Gilbert, Lester; Wills, Gary B.

    2013-01-01

    This research investigates the factors that affect a students' take-up and continued use of E-learning. A mathematical model was constructed by applying three grounded theories; Unified Theory of Acceptance and Use of Technology, Keller's ARCS model, and Expectancy Disconfirm Theory. The learning preference factor was included in the model.…

  20. Agent-based models for higher-order theory of mind

    NARCIS (Netherlands)

    de Weerd, Harmen; Verbrugge, Rineke; Verheij, Bart; Kamiński, Bogumił; Koloch, Grzegorz

    2014-01-01

    Agent-based models are a powerful tool for explaining the emergence of social phenomena in a society. In such models, individual agents typically have little cognitive ability. In this paper, we model agents with the cognitive ability to make use of theory of mind. People use this ability to reason

  1. Higher-dimensional cosmological model with variable gravitational constant and bulk viscosity in Lyra geometry

    Indian Academy of Sciences (India)

    G P Singh; R V Deshpande; T Singh

    2004-11-01

    We have studied five-dimensional homogeneous cosmological models with variable and bulk viscosity in Lyra geometry. Exact solutions for the field equations have been obtained and physical properties of the models are discussed. It has been observed that the results of new models are well within the observational limit.

  2. Lagrange-type modeling of continuous dielectric permittivity variation in double-higher-order volume integral equation method

    Science.gov (United States)

    Chobanyan, E.; Ilić, M. M.; Notaroš, B. M.

    2015-05-01

    A novel double-higher-order entire-domain volume integral equation (VIE) technique for efficient analysis of electromagnetic structures with continuously inhomogeneous dielectric materials is presented. The technique takes advantage of large curved hexahedral discretization elements—enabled by double-higher-order modeling (higher-order modeling of both the geometry and the current)—in applications involving highly inhomogeneous dielectric bodies. Lagrange-type modeling of an arbitrary continuous variation of the equivalent complex permittivity of the dielectric throughout each VIE geometrical element is implemented, in place of piecewise homogeneous approximate models of the inhomogeneous structures. The technique combines the features of the previous double-higher-order piecewise homogeneous VIE method and continuously inhomogeneous finite element method (FEM). This appears to be the first implementation and demonstration of a VIE method with double-higher-order discretization elements and conformal modeling of inhomogeneous dielectric materials embedded within elements that are also higher (arbitrary) order (with arbitrary material-representation orders within each curved and large VIE element). The new technique is validated and evaluated by comparisons with a continuously inhomogeneous double-higher-order FEM technique, a piecewise homogeneous version of the double-higher-order VIE technique, and a commercial piecewise homogeneous FEM code. The examples include two real-world applications involving continuously inhomogeneous permittivity profiles: scattering from an egg-shaped melting hailstone and near-field analysis of a Luneburg lens, illuminated by a corrugated horn antenna. The results show that the new technique is more efficient and ensures considerable reductions in the number of unknowns and computational time when compared to the three alternative approaches.

  3. Perspectives on open access high resolution digital elevation models to produce global flood hazard layers

    Science.gov (United States)

    Sampson, Christopher; Smith, Andrew; Bates, Paul; Neal, Jeffrey; Trigg, Mark

    2015-12-01

    Global flood hazard models have recently become a reality thanks to the release of open access global digital elevation models, the development of simplified and highly efficient flow algorithms, and the steady increase in computational power. In this commentary we argue that although the availability of open access global terrain data has been critical in enabling the development of such models, the relatively poor resolution and precision of these data now limit significantly our ability to estimate flood inundation and risk for the majority of the planet's surface. The difficulty of deriving an accurate 'bare-earth' terrain model due to the interaction of vegetation and urban structures with the satellite-based remote sensors means that global terrain data are often poorest in the areas where people, property (and thus vulnerability) are most concentrated. Furthermore, the current generation of open access global terrain models are over a decade old and many large floodplains, particularly those in developing countries, have undergone significant change in this time. There is therefore a pressing need for a new generation of high resolution and high vertical precision open access global digital elevation models to allow significantly improved global flood hazard models to be developed.

  4. Parsimonious higher-order hidden Markov models for improved array-CGH analysis with applications to Arabidopsis thaliana.

    Directory of Open Access Journals (Sweden)

    Michael Seifert

    2012-01-01

    Full Text Available Array-based comparative genomic hybridization (Array-CGH is an important technology in molecular biology for the detection of DNA copy number polymorphisms between closely related genomes. Hidden Markov Models (HMMs are popular tools for the analysis of Array-CGH data, but current methods are only based on first-order HMMs having constrained abilities to model spatial dependencies between measurements of closely adjacent chromosomal regions. Here, we develop parsimonious higher-order HMMs enabling the interpolation between a mixture model ignoring spatial dependencies and a higher-order HMM exhaustively modeling spatial dependencies. We apply parsimonious higher-order HMMs to the analysis of Array-CGH data of the accessions C24 and Col-0 of the model plant Arabidopsis thaliana. We compare these models against first-order HMMs and other existing methods using a reference of known deletions and sequence deviations. We find that parsimonious higher-order HMMs clearly improve the identification of these polymorphisms. Moreover, we perform a functional analysis of identified polymorphisms revealing novel details of genomic differences between C24 and Col-0. Additional model evaluations are done on widely considered Array-CGH data of human cell lines indicating that parsimonious HMMs are also well-suited for the analysis of non-plant specific data. All these results indicate that parsimonious higher-order HMMs are useful for Array-CGH analyses. An implementation of parsimonious higher-order HMMs is available as part of the open source Java library Jstacs (www.jstacs.de/index.php/PHHMM.

  5. Parsimonious higher-order hidden Markov models for improved array-CGH analysis with applications to Arabidopsis thaliana.

    Science.gov (United States)

    Seifert, Michael; Gohr, André; Strickert, Marc; Grosse, Ivo

    2012-01-01

    Array-based comparative genomic hybridization (Array-CGH) is an important technology in molecular biology for the detection of DNA copy number polymorphisms between closely related genomes. Hidden Markov Models (HMMs) are popular tools for the analysis of Array-CGH data, but current methods are only based on first-order HMMs having constrained abilities to model spatial dependencies between measurements of closely adjacent chromosomal regions. Here, we develop parsimonious higher-order HMMs enabling the interpolation between a mixture model ignoring spatial dependencies and a higher-order HMM exhaustively modeling spatial dependencies. We apply parsimonious higher-order HMMs to the analysis of Array-CGH data of the accessions C24 and Col-0 of the model plant Arabidopsis thaliana. We compare these models against first-order HMMs and other existing methods using a reference of known deletions and sequence deviations. We find that parsimonious higher-order HMMs clearly improve the identification of these polymorphisms. Moreover, we perform a functional analysis of identified polymorphisms revealing novel details of genomic differences between C24 and Col-0. Additional model evaluations are done on widely considered Array-CGH data of human cell lines indicating that parsimonious HMMs are also well-suited for the analysis of non-plant specific data. All these results indicate that parsimonious higher-order HMMs are useful for Array-CGH analyses. An implementation of parsimonious higher-order HMMs is available as part of the open source Java library Jstacs (www.jstacs.de/index.php/PHHMM).

  6. Spectra of produced particles at CERN SPS heavy-ion collisions from a parton-cascade model

    CERN Document Server

    Srivastava, D K; Srivastava, Dinesh Kumar; Geiger, Klaus

    1998-01-01

    We evaluate the spectra of produced particles (pions, kaons, antiprotons) from partonic cascades which may develop in the wake of heavy-ion collisions at CERN SPS energies and which may hadronize by formation of clusters which decay into hadrons. Using the experimental data obtained by NA35 and NA44 collaborations for S+S and Pb+Pb collisions, we conclude that the Monte Carlo implementation of the recently developed parton-cascade/cluster-hadronization model provides a reasonable description of the distributions of the particles produced in such collisions. While the rapidity distribution of the mid-rapidity protons is described reasonably well, their transverse momentum distribution falls too rapidly compared to the experimental values, implying a significant effect of final state scattering among the produced hadrons neglected so far.

  7. Higher Order Modeling in Hybrid Approaches to the Computation of Electromagnetic Fields

    Science.gov (United States)

    Wilton, Donald R.; Fink, Patrick W.; Graglia, Roberto D.

    2000-01-01

    Higher order geometry representations and interpolatory basis functions for computational electromagnetics are reviewed. Two types of vector-valued basis functions are described: curl-conforming bases, used primarily in finite element solutions, and divergence-conforming bases used primarily in integral equation formulations. Both sets satisfy Nedelec constraints, which optimally reduce the number of degrees of freedom required for a given order. Results are presented illustrating the improved accuracy and convergence properties of higher order representations for hybrid integral equation and finite element methods.

  8. Modeling Mechanical Properties of Aluminum Composite Produced Using Stir Casting Method

    Directory of Open Access Journals (Sweden)

    Muhammad Hayat Jokhio

    2011-01-01

    Full Text Available ANN (Artificial Neural Networks modeling methodology was adopted for predicting mechanical properties of aluminum cast composite materials. For this purpose aluminum alloy were developed using conventional foundry method. The composite materials have complex nature which posses the nonlinear relationship among heat treatment, processing parameters, and composition and affects their mechanical properties. These nonlinear relation ships with properties can more efficiently be modeled by ANNs. Neural networks modeling needs sufficient data base consisting of mechanical properties, chemical composition and processing parameters. Such data base is not available for modeling. Therefore, a large range of experimental work was carried out for the development of aluminum composite materials. Alloys containing Cu, Mg and Zn as matrix were reinforced with 1- 15% Al2O3 particles using stir casting method. Alloys composites were cast in a metal mold. More than eighty standard samples were prepared for tensile tests. Sixty samples were given solution treatments at 580oC for half an hour and tempered at 120oC for 24 hours. The samples were characterized to investigate mechanical properties using Scanning Electron Microscope, X-Ray Spectrometer, Optical Metallurgical Microscope, Vickers Hardness, Universal Testing Machine and Abrasive Wear Testing Machine. A MLP (Multilayer Perceptron feedforward was developed and used for modeling purpose. Training, testing and validation of the model were carried out using back propagation learning algorithm. The modeling results show that an architecture of 14 inputs with 9 hidden neurons and 4 outputs which includes the tensile strength, elongation, hardness and abrasive wear resistance gives reasonably accurate results with an error within the range of 2-7 % in training, testing and validation.

  9. Anti-Lipid IgG Antibodies Are Produced via Germinal Centers in a Murine Model Resembling Human Lupus

    Science.gov (United States)

    Wong-Baeza, Carlos; Reséndiz-Mora, Albany; Donis-Maturano, Luis; Wong-Baeza, Isabel; Zárate-Neira, Luz; Yam-Puc, Juan Carlos; Calderón-Amador, Juana; Medina, Yolanda; Wong, Carlos; Baeza, Isabel; Flores-Romo, Leopoldo

    2016-01-01

    Anti-lipid IgG antibodies are produced in some mycobacterial infections and in certain autoimmune diseases [such as anti-phospholipid syndrome, systemic lupus erythematosus (SLE)]. However, few studies have addressed the B cell responses underlying the production of these immunoglobulins. Anti-lipid IgG antibodies are consistently found in a murine model resembling human lupus induced by chlorpromazine-stabilized non-bilayer phospholipid arrangements (NPA). NPA are transitory lipid associations found in the membranes of most cells; when NPA are stabilized they can become immunogenic and induce specific IgG antibodies, which appear to be involved in the development of the mouse model of lupus. Of note, anti-NPA antibodies are also detected in patients with SLE and leprosy. We used this model of lupus to investigate in vivo the cellular mechanisms that lead to the production of anti-lipid, class-switched IgG antibodies. In this murine lupus model, we found plasma cells (Gr1−, CD19−, CD138+) producing NPA-specific IgGs in the draining lymph nodes, the spleen, and the bone marrow. We also found a significant number of germinal center B cells (IgD−, CD19+, PNA+) specific for NPA in the draining lymph nodes and the spleen, and we identified in situ the presence of NPA in these germinal centers. By contrast, very few NPA-specific, extrafollicular reaction B cells (B220+, Blimp1+) were found. Moreover, when assessing the anti-NPA IgG antibodies produced during the experimental protocol, we found that the affinity of these antibodies progressively increased over time. Altogether, our data indicate that, in this murine model resembling human lupus, B cells produce anti-NPA IgG antibodies mainly via germinal centers. PMID:27746783

  10. O(3) Non-linear $\\sigma$ model with Hopf term and Higher spin theories

    CERN Document Server

    Govindarajan, T R; Shaji, N; Sivakumar, M

    1993-01-01

    Following our earlier work we argue in detail for the equivalence of the nonlinear $\\sigma$ model with Hopf term at~$\\theta=\\pi/2s$ ~and an interacting spin-s theory. We give an ansatz for spin-s operators in the $\\sigma$ model and show the equivalence of the correlation functions.We also show the relation between topological and Noether currents. We obtain the Lorentz and discrete transformation properties of the spin-s operator from the fields of the $\\sigma$ model. We also explore the connection of this model with Quantum Hall Fluids.

  11. Construction and exact solution of a nonlinear quantum field model in quasi-higher dimension

    Energy Technology Data Exchange (ETDEWEB)

    Kundu, Anjan, E-mail: anjan.kundu@saha.ac.in

    2015-10-15

    Nonperturbative exact solutions are allowed for quantum integrable models in one space-dimension. Going beyond this class we propose an alternative Lax matrix approach, exploiting the hidden multi-space–time concept in integrable systems and construct a novel nonlinear Schrödinger quantum field model in quasi-two dimensions. An intriguing field commutator is discovered, confirming the integrability of the model and yielding its exact Bethe ansatz solution with rich scattering and bound-state properties. The universality of the scheme is expected to cover diverse models, opening up a new direction in the field.

  12. Modeling laser produced plasmas with smoothed particle hydrodynamics for next generation advanced light sources

    Science.gov (United States)

    Holladay, Robert; Griffith, Alec; Murillo, Michael S.

    2016-10-01

    A computational model has been developed to study the evolution of a plasma generated by next-generation advanced light sources such as SLAC's LCLS and LANL's proposed MaRIE. Smoothed Particle Hydrodynamics (SPH) is used to model the plasma evolution because of the ease with which it handles the open boundary conditions and large deformations associated with these experiments. Our work extends the basic SPH method by utilizing a two-fluid model of an electron-ion plasma that also incorporates time dependent ionization and recombination by allowing the SPH fluid particles to have an evolving mass based on the mean ionization state of the plasma. Additionally, inter-species heating, thermal conduction, and electric fields are also accounted for. The effects of various initial conditions and model parameters will be presented, with the goal of using this framework to develop a model that can be used in the design and interpretation of future experiments. This work was supported by the Los Alamos National Laboratory Computational Physics Workshop.

  13. Theoretical Models for Producing Circularly Polarized Radiation in Extragalactic Radio Sources

    CERN Document Server

    Wardle, J F C; Wardle, John F. C.; Homan, Daniel C.

    2003-01-01

    We discuss the production of circular polarization in compact radio sources both by the intrinsic mechanism and by Faraday conversion. We pay particular attention to the magnetic field structure, considering partially ordered fiel ds and Laing sheets, and distinguishing between uniform and unidirectional fields. (The latter can be constrained b y flux conservation arguments.) In most cases, Faraday conversion is the more important mechanism. Conversion opera tes on Stokes U, which can be generated by internal Faraday rotation, or by magnetic field fluctuations, which can therefore produce circular polarization even in a pure pair plasma. We also show that the spectrum of circular pola rization in an inhomogeneous jet can be quite different from that in a uniform source, being flat or even inverted.

  14. An Integrated Model of Influence: Use of Assessment Data in Higher Education

    Science.gov (United States)

    Jonson, Jessica L.; Guetterman, Tim; Thompson, Robert J., Jr.

    2014-01-01

    A fundamental goal of student learning outcomes assessment in higher education is to use student learning evidence in decision making to improve educational programs. Such use of assessment findings, however, is atypical. This article argues that a narrow conception of use contributes to this conclusion and an accurate appraisal of the…

  15. Embedding Support for Students Transitioning into Higher Education: Evaluation of a New Model

    Science.gov (United States)

    Hebdon, Sharon

    2015-01-01

    The Learning Academic Skills Support program was designed to improve progression and retention rates for students articulating from vocational education into the Bachelor of Hospitality Management at Holmesglen Institute. The program is scheduled around the student experience during their first semester in higher education and incorporates…

  16. The study of gravitational collapse model in higher dimensional space-time

    CERN Document Server

    Debnath, U; Debnath, Ujjal; Chakraborty, Subenoy

    2003-01-01

    We investigate the end state of the gravitational collapse of an inhomogeneous dust cloud in higher dimensional space-time. The naked singularities are shown to be developing as the final outcome of non-marginally bound collapse. The naked singularities are found to be gravitationally strong in the sense of Tipler .

  17. Knowledge Management, Human Resource Management, and Higher Education: A Theoretical Model

    Science.gov (United States)

    Brewer, Peggy D.; Brewer, Kristen L.

    2010-01-01

    Much has been written on the importance of knowledge management, the challenges facing organizations, and the important human resource management activities involved in assuring the acquisition and transfer of knowledge. Higher business education plays an important role in preparing students to assume the knowledge management and human resource…

  18. A Model of Leadership in Integrating Educational Technology in Higher Education

    Science.gov (United States)

    Markova, Mariya

    2014-01-01

    The potential impacts and implications of technology on the professional lives of instructors in higher education, and the role of leadership in integrating educational technology, present a variety of complexities and challenges. The purpose of this paper is to identify the reasons why faculty members are not fully embracing technology and what…

  19. Business Models of High Performance Computing Centres in Higher Education in Europe

    Science.gov (United States)

    Eurich, Markus; Calleja, Paul; Boutellier, Roman

    2013-01-01

    High performance computing (HPC) service centres are a vital part of the academic infrastructure of higher education organisations. However, despite their importance for research and the necessary high capital expenditures, business research on HPC service centres is mostly missing. From a business perspective, it is important to find an answer to…

  20. Rethinking Business Models for 21st Century Higher Education: A European Perspective

    Science.gov (United States)

    Lichy, Jessica; Enström, Rickard

    2015-01-01

    The late 20th century was an era of social, economic, technological, and political change, resulting in significant shifts in the perception of enlightenment, knowledge, and education. The impact of these changes have become quite apparent in higher education where there is now mounting pressure for faculty to deliver high quality education to an…

  1. Academic Dishonesty in Distance Higher Education: Challenges and Models for Moral Education in the Digital Era

    Science.gov (United States)

    Farisi, Mohammad Imam

    2013-01-01

    Today, in the era of open access to digital-based information and communication, one of the biggest challenges in higher education to realize moral education and to build academic culture and integrity is the emergence of academic dishonesty behaviors among academic members. The paper describes academic dishonesty behaviors in Distance Higher…

  2. Knowledge Management, Human Resource Management, and Higher Education: A Theoretical Model

    Science.gov (United States)

    Brewer, Peggy D.; Brewer, Kristen L.

    2010-01-01

    Much has been written on the importance of knowledge management, the challenges facing organizations, and the important human resource management activities involved in assuring the acquisition and transfer of knowledge. Higher business education plays an important role in preparing students to assume the knowledge management and human resource…

  3. Community Engagement by Higher Education Institutions--A Practical Model and Guidelines

    Science.gov (United States)

    Coetzee, E.

    2012-01-01

    This article analyses the definition and understanding of the concept community engagement as one of the focal areas of Higher Education Institutions in South Africa. It captures the importance of a proper approach towards community engagement and contributes towards a practical method to guide the reader through the complex interaction between…

  4. Higher Education in East Asia and Singapore: Rise of the Confucian Model

    Science.gov (United States)

    Marginson, Simon

    2011-01-01

    The paper reviews Asia-Pacific higher education and university research, focusing principally on the "Confucian" education nations Japan, Korea, China, Hong Kong China, Taiwan, Singapore and Vietnam. Except for Vietnam, these systems exhibit a special developmental dynamism--still playing out everywhere except Japan--and have created a…

  5. A Hybrid PO - Higher-Order Hierarchical MoM Formulation using Curvilinear Geometry Modeling

    DEFF Research Database (Denmark)

    Jørgensen, E.; Meincke, Peter; Breinbjerg, Olav

    2003-01-01

    A very efficient hybrid PO-MoM method has been presented. In contrast to existing methods, the present solution employs higher-order hierarchical basis functions to discretize the MoM and PO currents. This allows to reduce the number of basis functions in both the PO and MoM regions considerably...

  6. LeaD-In: A Cultural Change Model for Peer Review of Teaching in Higher Education

    Science.gov (United States)

    Barnard, A.; Nash, R.; McEvoy, K.; Shannon, S.; Waters, C.; Rochester, S.; Bolt, S.

    2015-01-01

    Peer review of teaching is recognized increasingly as one strategy for academic development even though historically peer review of teaching is often unsupported by policy, action and culture in many Australian universities. Higher education leaders report that academics generally do not engage with peer review of teaching in a systematic or…

  7. A Delphi Study of Effective Practices for Developing Competency-Based Learning Models in Higher Education

    Science.gov (United States)

    McIntyre-Hite, Lisa

    2016-01-01

    Currently, there is an increase in competency-based education programs in higher education institutions in response to student and employer needs. However, research is lacking on effective practices for developing competencies, assessments, and learning resources for these programs. The purpose of this qualitative Delphi study was to gather expert…

  8. Business Models of High Performance Computing Centres in Higher Education in Europe

    Science.gov (United States)

    Eurich, Markus; Calleja, Paul; Boutellier, Roman

    2013-01-01

    High performance computing (HPC) service centres are a vital part of the academic infrastructure of higher education organisations. However, despite their importance for research and the necessary high capital expenditures, business research on HPC service centres is mostly missing. From a business perspective, it is important to find an answer to…

  9. The EFQM Excellence Model[R]: Higher Education's Latest Management Fad?

    Science.gov (United States)

    Temple, Paul

    2005-01-01

    Robert Birnbaum argues that higher education tends to adopt management fads -- newly conceived techniques enjoying brief popularity but which fail to live up to their promoters claims at the point when the corporate sector and government are discarding them. Although fads may have failed in these sectors because of various reasons, their failure…

  10. Recovering Old Stereoscopic Negatives and Producing Digital 3d Models of Former Appearances of Historic Buildings

    Science.gov (United States)

    Rodríguez Miranda, Á.; Valle Melón, J. M.

    2017-02-01

    Three-dimensional models with photographic textures have become a usual product for the study and dissemination of elements of heritage. The interest for cultural heritage also includes evolution along time; therefore, apart from the 3D models of the current state, it is interesting to be able to generate models representing how they were in the past. To that end, it is necessary to resort to archive information corresponding to the moments that we want to visualize. This text analyses the possibilities of generating 3D models of surfaces with photographic textures from old collections of analog negatives coming from works of terrestrial stereoscopic photogrammetry of historic buildings. The case studies presented refer to the geometric documentation of a small hermitage (done in 1996) and two sections of a wall (year 2000). The procedure starts with the digitization of the film negatives and the processing of the images generated, after which a combination of different methods for 3D reconstruction and texture wrapping are applied: techniques working simultaneously with several images (such as the algorithms of Structure from Motion - SfM) and single image techniques (such as the reconstruction based on vanishing points). Then, the features of the obtained models are described according to the geometric accuracy, completeness and aesthetic quality. In this way, it is possible to establish the real applicability of the models in order to be useful for the aforementioned historical studies and dissemination purposes. The text also wants to draw attention to the importance of preserving the documentary heritage available in the collections of negatives in archival custody and to the increasing difficulty of using them due to: (1) problems of access and physical conservation, (2) obsolescence of the equipment for scanning and stereoplotting and (3) the fact that the software for processing digitized photographs is discontinued.

  11. Distribution and Orientation of Carbon Fibers in Polylactic Acid Parts Produced by Fused Deposition Modeling

    DEFF Research Database (Denmark)

    Hofstätter, Thomas; W. Gutmann, Ingomar; Koch, Thomas

    2016-01-01

    The aim of this paper is the understanding of the fiber orientation by investigations in respect to the inner configuration of a polylactic acid matrix reinforced with short carbon fibers after a fused deposition modeling extrusion process. The final parts were analyzed by X-ray, tomography, and ......, and magnetic resonance imaging allowing a resolved orientation of the fibers and distribution within the part. The research contributes to the understanding of the fiber orientation and fiber reinforcement of fused deposition modeling parts in additive manufacturing....

  12. Development of a Novel Simplified PBPK Absorption Model to Explain the Higher Relative Bioavailability of the OROS® Formulation of Oxybutynin.

    Science.gov (United States)

    Olivares-Morales, Andrés; Ghosh, Avijit; Aarons, Leon; Rostami-Hodjegan, Amin

    2016-11-01

    A new minimal Segmented Transit and Absorption model (mSAT) model has been recently proposed and combined with intrinsic intestinal effective permeability (P eff,int ) to predict the regional gastrointestinal (GI) absorption (f abs ) of several drugs. Herein, this model was extended and applied for the prediction of oral bioavailability and pharmacokinetics of oxybutynin and its enantiomers to provide a mechanistic explanation of the higher relative bioavailability observed for oxybutynin's modified-release OROS® formulation compared to its immediate-release (IR) counterpart. The expansion of the model involved the incorporation of mechanistic equations for the prediction of release, transit, dissolution, permeation and first-pass metabolism. The predicted pharmacokinetics of oxybutynin enantiomers after oral administration for both the IR and OROS® formulations were in close agreement with the observed data. The predicted absolute bioavailability for the IR formulation was within 5% of the observed value, and the model adequately predicted the higher relative bioavailability observed for the OROS® formulation vs. the IR counterpart. From the model predictions, it can be noticed that the higher bioavailability observed for the OROS® formulation was mainly attributable to differences in the intestinal availability (F G ) rather than due to a higher colonic f abs , thus confirming previous hypotheses. The predicted f abs was almost 70% lower for the OROS® formulation compared to the IR formulation, whereas the F G was almost eightfold higher than in the IR formulation. These results provide further support to the hypothesis of an increased F G as the main factor responsible for the higher bioavailability of oxybutynin's OROS® formulation vs. the IR.

  13. Higher dimensional models of cross-coupled oscillators and application to design

    KAUST Repository

    Elwakil, Ahmed S.

    2010-06-01

    We present four-dimensional and five-dimensional models for classical cross-coupled LC oscillators. Using these models, sinusoidal oscillation condition, frequency and amplitude can be found. Further, undesired behaviors such as relaxation-mode oscillations and latchup can be explained and detected. A simple graphical design procedure is also described. © 2010 World Scientific Publishing Company.

  14. Alternative Models of Entrance Exams and Access to Higher Education: The Case of the Czech Republic

    Science.gov (United States)

    Konecny, Tomas; Basl, Josef; Myslivecek, Jan; Simonova, Natalie

    2012-01-01

    The study compares the potential effects of a university admission exam model based on program-specific knowledge and an alternative model relying on general study aptitude (GSA) in the context of a strongly stratified educational system with considerable excess of demand over supply of university education. Using results of the "Sonda…

  15. The Learning-Teaching Nexus: Modelling the Learning-Teaching Relationship in Higher Education

    Science.gov (United States)

    Knewstubb, Bernadette

    2016-01-01

    The teaching-learning relationship is often described as a conversation. However, many models of teaching and learning depict the worlds of teacher and learner as enclosed and inaccessible, linked by apparently transferred communicative meanings. A new interdisciplinary learning-teaching nexus (LTN) model combines perspectives from higher…

  16. Higher-order effects in asset-pricing models with long-run risks

    NARCIS (Netherlands)

    Pohl, W.; Schmedders, K.; Wilms, Ole

    2017-01-01

    This paper shows that the latest generation of asset pricing models with long-run risk exhibits economically significant nonlinearities, and thus the ubiquitous Campbell--Shiller log-linearization can generate large numerical errors. These errors in turn translate to considerable errors in the model

  17. A non-local evolution equation model of cell-cell adhesion in higher dimensional space.

    Science.gov (United States)

    Dyson, Janet; Gourley, Stephen A; Webb, Glenn F

    2013-01-01

    A model for cell-cell adhesion, based on an equation originally proposed by Armstrong et al. [A continuum approach to modelling cell-cell adhesion, J. Theor. Biol. 243 (2006), pp. 98-113], is considered. The model consists of a nonlinear partial differential equation for the cell density in an N-dimensional infinite domain. It has a non-local flux term which models the component of cell motion attributable to cells having formed bonds with other nearby cells. Using the theory of fractional powers of analytic semigroup generators and working in spaces with bounded uniformly continuous derivatives, the local existence of classical solutions is proved. Positivity and boundedness of solutions is then established, leading to global existence of solutions. Finally, the asymptotic behaviour of solutions about the spatially uniform state is considered. The model is illustrated by simulations that can be applied to in vitro wound closure experiments.

  18. Instructions for producing a mouse model of glucocorticoid-induced osteoporosis

    DEFF Research Database (Denmark)

    Thiele, S.; Baschant, U.; Rauch, A.

    2014-01-01

    with a compromised bone quality and an increased fracture risk. At the cellular level, glucocorticoids suppress bone formation and stimulate bone resorption, which leads to loss of bone mass. To investigate the underlying mechanisms and new therapeutic strategies, the in vivo model for glucocorticoid-induced bone...

  19. Distribution and Orientation of Carbon Fibers in Polylactic Acid Parts Produced by Fused Deposition Modeling

    DEFF Research Database (Denmark)

    Hofstätter, Thomas; W. Gutmann, Ingomar; Koch, Thomas

    2016-01-01

    The aim of this paper is the understanding of the fiber orientation by investigations in respect to the inner configuration of a polylactic acid matrix reinforced with short carbon fibers after a fused deposition modeling extrusion process. The final parts were analyzed by X-ray, tomography, and ...

  20. Dynamical symmetry restoration for a higher-derivative four-fermion model in an external electromagnetic field

    CERN Document Server

    Elizalde, E; Odintsov, S D; Shilnov, Yu I; Shil'nov, Yu. I.

    1998-01-01

    A four-fermion model with additional higher-derivative terms is investigated in an external electromagnetic field. The effective potential in the leading order of large-N expansion is calculated in external constant magnetic and electric fields. It is shown that, in contrast to the former results concerning the universal character of "magnetic catalysis" in dynamical symmetry breaking, in the present higher-derivative model the magnetic field restores chiral symmetry broken initially on the tree level. Numerical results describing a second-order phase transition that accompanies the symmetry restoration at the quantum level are presented.

  1. Stochastic periodic solution of a non-autonomous toxic-producing phytoplankton allelopathy model with environmental fluctuation

    Science.gov (United States)

    Zhao, Yu; Yuan, Sanling; Zhang, Tonghua

    2017-03-01

    Phytoplankton allelopathy is an ecological phenomenon that concerns the interaction among toxic-producing phytoplankton. Recently, researchers pay great attention to whether the cyclic outbreaks of the harmful algal blooms are related with the allelopathy in a random fluctuating environment. In this paper, we are particularly interested in a non-autonomous toxic-producing phytoplankton allelopathy model with environmental fluctuation. For the model, we first consider the existence of the global positive solution and the boundary periodic solution. Then, by using Khasminskii's method and Lyapunov function, we derive the sufficient conditions for the existence of the nontrivial positive stochastically periodic solution. Our results show that the allelopathic effect plays an important role in the existence of the stochastic periodic solution, for example it can lead to the decrease of the peaks of the cyclic outbreaks of the harmful algal blooms. Numerical simulations are carried out to support our theoretical results.

  2. The Use of Perinatal 6-Hydroxydopamine to Produce a Rodent Model of Lesch-Nyhan Disease.

    Science.gov (United States)

    Knapp, Darin J; Breese, George R

    Lesch-Nyhan disease is a neurologically, metabolically, and behaviorally devastating condition that has eluded complete characterization and adequate treatment. While it is known that the disease is intimately associated with dysfunction of the hypoxanthine phosphoribosyltransferase 1 (HPRT1) gene that codes for an enzyme of purine metabolism (hypoxanthine-guanine phosphoribosyltransferase) and is associated with neurological, behavioral, as well as metabolic dysfunction, the mechanisms of the neurobehavioral manifestations are as yet unclear. However, discoveries over the past few decades not only have created useful novel animal models (e.g., the HPRT-deficient mouse and the serendipitously discovered perinatal 6-hydroxydopamine (6-OHDA lesion model), but also have expanded into epigenetic, genomic, and proteomic approaches to better understand the mechanisms underlying this disease. The perinatal 6-OHDA model, in addition to modeling self-injury and dopamine depletion in the clinical condition, also underscores the profound importance of development in the differential course of maladaptive progression in the face of a common/single neurotoxic insult at different ages. Recent developments from clinical and basic science efforts attest to the fact that while the disease would seem to have a simple single gene defect at its core, the manifestations of this defect are profound and unexpectedly diverse. Future efforts employing the 6-OHDA model and others in the context of the novel technologies of genome editing, chemo- and opto-genetics, epigenetics, and further studies on the mechanisms of stress-induced maladaptations in brain all hold promise in taking our understanding of this disease to the next level.

  3. A mathematical model for surface roughness of fluidic channels produced by grinding aided electrochemical discharge machining (G-ECDM)

    OpenAIRE

    Ladeesh V. G.; Manu R

    2017-01-01

    Grinding aided electrochemical discharge machining is a hybrid technique, which combines the grinding action of an abrasive tool and thermal effects of electrochemical discharges to remove material from the workpiece for producing complex contours. The present study focuses on developing fluidic channels on borosilicate glass using G-ECDM and attempts to develop a mathematical model for surface roughness of the machined channel. Preliminary experiments are conducted to study the effect of mac...

  4. Copepod flow modes and modulation: a modelling study of the water currents produced by an unsteadily swimming copepod

    OpenAIRE

    2007-01-01

    Video observation has shown that feeding-current-producing calanoid copepods modulate their feeding currents by displaying a sequence of different swimming behaviours during a time period of up to tens of seconds. In order to understand the feeding-current modulation process, we numerically modelled the steady feeding currents for different modes of observed copepod motion behaviours (i.e. free sinking, partial sinking, hovering, vertical swimming upward and horizontal swimming backward or fo...

  5. Tensile Properties Characterization of AlSi10Mg Parts Produced by Direct Metal Laser Sintering via Nested Effects Modeling

    OpenAIRE

    Biagio Palumbo; Francesco Del Re; Massimo Martorelli; Antonio Lanzotti; Pasquale Corrado

    2017-01-01

    A statistical approach for the characterization of Additive Manufacturing (AM) processes is presented in this paper. Design of Experiments (DOE) and ANalysis of VAriance (ANOVA), both based on Nested Effects Modeling (NEM) technique, are adopted to assess the effect of different laser exposure strategies on physical and mechanical properties of AlSi10Mg parts produced by Direct Metal Laser Sintering (DMLS). Due to the wide industrial interest in AM technologies in many different fields, it is...

  6. China’s Higher Education Engagement with Africa: A Different Partnership and Cooperation Model?

    Directory of Open Access Journals (Sweden)

    Kenneth King

    2014-11-01

    Full Text Available What is the nature of China’s educational partnerships with Africa? This chapter examines China’s investment in human resource development in Africa, especially in higher education, through several programmes including long- and short-term training of Africans in China, Confucius Institutes, stand-alone projects, and the 20+20 scheme for higher education cooperation between China and Africa. It investigates several apparent differences between China’s aid discourse and practice and those of traditional Organisation for Economic Co-operation and Development (OECD donors. It asks how the enduring continuity of China’s discourse on mutual benefit and common good in educational aid can be explained. Can what looks like a one-way partnership in terms of financing really, in fact, be symmetrical?

  7. SERVQUAL MODEL IMPLEMENTATION FOR EVALUATING QUALITY SERVICE OF THE LIBRARY OF HIGHER EDUCATIONINSTITUTION IN BOTUCATU REGION

    OpenAIRE

    2014-01-01

    Currently technology colleges are growing and gaining market share. So, it is of paramount importance a careful evaluation of the most important components in an institution of higher education, the library, which is fundamental for the development of future professionals. Therefore, the implementation of a tool to measure and compare results through user satisfaction in relation to services provided to a particular service is required. SERVQUAL is a measurement tool, used in t...

  8. Building a Classification Model for Enrollment In Higher Educational Courses using Data Mining Techniques

    OpenAIRE

    Saini, Priyanka

    2014-01-01

    Data Mining is the process of extracting useful patterns from the huge amount of database and many data mining techniques are used for mining these patterns. Recently, one of the remarkable facts in higher educational institute is the rapid growth data and this educational data is expanding quickly without any advantage to the educational management. The main aim of the management is to refine the education standard; therefore by applying the various data mining techniques on this data one ca...

  9. Higher education policy: A case study on quality assessment towards a model of university management

    OpenAIRE

    Silva,Marcelo Fernandes da; Borges,Luis Henrique; Borges,Maria Soledade Gomes; Elias,Inara Pena Barbosa

    2017-01-01

    Abstract: The institutional self-assessment is considered herein in the context of higher education assessment as a university management tool. The paper aims to present and discuss the impact of the results of an institutional self-assessment committee in the management of pedagogical and administrative issues of a Brazilian university in accordance with contemporary education policy. Four consecutive annual reports were reviewed to demonstrate the impacts of institutional self-evaluation an...

  10. A descriptive model of a universe containing matter which produces gravitational radiation

    Energy Technology Data Exchange (ETDEWEB)

    Chauvet, P.; Cervantes-Cota, J. (Universidad Autonoma Metropolitana-Iztapalapa, Mexico City (Mexico)); Klapp, J. (Universidad Autonoma Metropolitana-Iztapalapa, Mexico City (Mexico) Instituto Nacional de Investigaciones Nucleares, Mexico City (Mexico))

    1993-04-01

    The dynamics of the production of relative high frequency gravitational waves by astrophysical events taking place within the galaxies in the cosmological context can be well represented by a phenomenological description of the generating processes through a radiation energy profile that contains two adjustable parameters. This profile gives a relation between the total pressure and energy density of the matter generating gravitational radiation together with the waves themselves, both treated as ordinary hydrodynamic fluids. The resulting cosmological models then represent, in a descriptive way only, universes filled with two interacting fluids: on the one hand gravitational radiation, and the matter which emits it but does not reabsorb it, on the other. It is shown that the dynamic effects of the model can be significant, even if the conversion rate of matter into gravitational radiation is relatively small. 16 refs., 5 figs., 1 tab.

  11. Reaction kinetic model for a recent co-produced water treatment technology

    Institute of Scientific and Technical Information of China (English)

    Abdulwahab M Ali Tuwati; Maohong Fan; Mark A. Bentley

    2011-01-01

    With the increasing demand for fossil based energy and implementation of progressively strict environmental pollution control standards, treatment of a large amount of co-produced waters (CPWs) from fossil based energy production has become increasingly important.Removal of bicarbonate with H2SO4 has been recently studied as a simple and cost-effective method to decrease the alkalinity of CPWs.The present work investigates the kinetics of the reaction between H2SO4 and NaHCO3, which could provide the base for scaling-up the CPW treatment technology.Based on the measured quantity change of the CO2 gas generated from the reaction between H2SO4 and NaHCO3 with time under specified initial reaction conditions, the reaction orders with respect to H2SO4 and NaHCO3 were determined.Experiments were also conducted within the temperature of 15-30℃ to find various global rate coefficients of the reaction to calculate the activation energy and the pre-exponential factor of the empirical Arrhenius form of the bicarbonate removal reaction,which are 197.7 kJ/mol and 3.13× 1034 (mol-3.7×L3.7×sec-1), respectively.

  12. Notified Access: Extending Remote Memory Access Programming Models for Producer-Consumer Synchronization

    KAUST Repository

    Belli, Roberto

    2015-05-01

    Remote Memory Access (RMA) programming enables direct access to low-level hardware features to achieve high performance for distributed-memory programs. However, the design of RMA programming schemes focuses on the memory access and less on the synchronization. For example, in contemporary RMA programming systems, the widely used producer-consumer pattern can only be implemented inefficiently, incurring in an overhead of an additional round-trip message. We propose Notified Access, a scheme where the target process of an access can receive a completion notification. This scheme enables direct and efficient synchronization with a minimum number of messages. We implement our scheme in an open source MPI-3 RMA library and demonstrate lower overheads (two cache misses) than other point-to-point synchronization mechanisms for each notification. We also evaluate our implementation on three real-world benchmarks, a stencil computation, a tree computation, and a Colicky factorization implemented with tasks. Our scheme always performs better than traditional message passing and other existing RMA synchronization schemes, providing up to 50% speedup on small messages. Our analysis shows that Notified Access is a valuable primitive for any RMA system. Furthermore, we provide guidance for the design of low-level network interfaces to support Notified Access efficiently.

  13. Using higher-order Markov models to reveal flow-based communities in networks

    CERN Document Server

    Salnikov, Vsevolod; Lambiotte, Renaud

    2016-01-01

    Complex systems made of interacting elements are commonly abstracted as networks, in which nodes are associated with dynamic state variables, whose evolution is driven by interactions mediated by the edges. Markov processes have been the prevailing paradigm to model such a network-based dynamics, for instance in the form of random walks or other types of diffusions. Despite the success of this modelling perspective for numerous applications, it represents an over-simplification of several real-world systems. Importantly, simple Markov models lack memory in their dynamics, an assumption often not realistic in practice. Here, we explore possibilities to enrich the system description by means of second-order Markov models, exploiting empirical pathway information. We focus on the problem of community detection and show that standard network algorithms can be generalized in order to extract novel temporal information about the system under investigation. We also apply our methodology to temporal networks, where w...

  14. Reentry produced by small-scale heterogeneities in a discrete model of cardiac tissue

    Science.gov (United States)

    Alonso, Sergio; Bär, Markus

    2016-06-01

    Reentries are reexcitations of cardiac tissue after the passing of an excitation wave which can cause dangerous arrhythmias like tachycardia or life-threatening heart failures like fibrillation. The heart is formed by a network of cells connected by gap junctions. Under ischemic conditions some of the cells lose their connections, because gap junctions are blocked and the excitability is decreased. We model a circular region of the tissue where a fraction of connections among individual cells are removed and substituted by non-conducting material in a two-dimensional (2D) discrete model of a heterogeneous excitable medium with local kinetics based on electrophysiology. Thus, two neighbouring cells are connected (disconnected) with a probability ϕ (1 - ϕ). Such a region is assumed to be surrounded by homogeneous tissue. The circular heterogeneous area is shown to act as a source of new waves which reenter into the tissue and reexcitate the whole domain. We employ the Fenton-Karma equations to model the action potential for the local kinetics of the discrete nodes to study the statistics of the reentries in two dimensional networks with different topologies. We conclude that the probability of reentry is determined by the proximity of the fraction of disrupted connections between neighboring nodes (“cells”) in the heterogeneous region to the percolation threshold.

  15. Economic feasibility of producing oysters using a small-scale Hawaiian fishpond model

    Directory of Open Access Journals (Sweden)

    Jessie Q. Chen

    2017-02-01

    Full Text Available Traditional fishpond aquaculture in Hawai‘i has declined since global trade provided access to cheaper, imported food. Farming non-native species like the Pacific oyster may prove more profitable than traditional species, and may help maintain the practice of fishpond aquaculture. Little literature exists on the economics of Hawai‘i’s oyster culture or the unique practices involved in fishpond-based production. Based on information supplied by a currently operating farm, we developed an enterprise budget for a model farm in order to 1 assess profitability, 2 determine sensitive input parameters, and 3 use stochastic modeling to determine the likelihood of different economic outcomes. The budget returned a marginally negative profit, with the bulk of operating costs from labor. Decision reversal analysis showed the model farm can be profitable with an increase in market price from US $1.25 to US $1.35 per oyster or a decrease in mortality rate from 50% to 45.9% – both are within reasonable reach in the near future.

  16. Modelling the risk of Taenia solium exposure from pork produced in western Kenya.

    Science.gov (United States)

    Thomas, Lian F; de Glanville, William A; Cook, Elizabeth A J; Bronsvoort, Barend M De C; Handel, Ian; Wamae, Claire N; Kariuki, Samuel; Fèvre, Eric M

    2017-02-17

    The tapeworm Taenia solium is the parasite responsible for neurocysticercosis, a neglected tropical disease of public health importance, thought to cause approximately 1/3 of epilepsy cases across endemic regions. The consumption of undercooked infected pork perpetuates the parasite's life-cycle through the establishment of adult tapeworm infections in the community. Reducing the risk associated with pork consumption in the developing world is therefore a public health priority. The aim of this study was to estimate the risk of any one pork meal in western Kenya containing a potentially infective T. solium cysticercus at the point of consumption, an aspect of the parasite transmission that has not been estimated before. To estimate this, we used a quantitative food chain risk assessment model built in the @RISK add-on to Microsoft Excel. This model indicates that any one pork meal consumed in western Kenya has a 0.006 (99% Uncertainty Interval (U.I). 0.0002-0.0164) probability of containing at least one viable T. solium cysticercus at the point of consumption and therefore being potentially infectious to humans. This equates to 22,282 (99% U.I. 622-64,134) potentially infective pork meals consumed in the course of one year within Busia District alone. This model indicates a high risk of T. solium infection associated with pork consumption in western Kenya and the work presented here can be built upon to investigate the efficacy of various mitigation strategies for this locality.

  17. The Use of Dynamic Stochastic Social Behavior Models to Produce Likelihood Functions for Risk Modeling of Proliferation and Terrorist Attacks

    Energy Technology Data Exchange (ETDEWEB)

    Young, Jonathan; Thompson, Sandra E.; Brothers, Alan J.; Whitney, Paul D.; Coles, Garill A.; Henderson, Cindy L.; Wolf, Katherine E.; Hoopes, Bonnie L.

    2008-12-01

    The ability to estimate the likelihood of future events based on current and historical data is essential to the decision making process of many government agencies. Successful predictions related to terror events and characterizing the risks will support development of options for countering these events. The predictive tasks involve both technical and social component models. The social components have presented a particularly difficult challenge. This paper outlines some technical considerations of this modeling activity. Both data and predictions associated with the technical and social models will likely be known with differing certainties or accuracies – a critical challenge is linking across these model domains while respecting this fundamental difference in certainty level. This paper will describe the technical approach being taken to develop the social model and identification of the significant interfaces between the technical and social modeling in the context of analysis of diversion of nuclear material.

  18. Improved prediction of higher heating value of biomass using an artificial neural network model based on proximate analysis.

    Science.gov (United States)

    Uzun, Harun; Yıldız, Zeynep; Goldfarb, Jillian L; Ceylan, Selim

    2017-06-01

    As biomass becomes more integrated into our energy feedstocks, the ability to predict its combustion enthalpies from routine data such as carbon, ash, and moisture content enables rapid decisions about utilization. The present work constructs a novel artificial neural network model with a 3-3-1 tangent sigmoid architecture to predict biomasses' higher heating values from only their proximate analyses, requiring minimal specificity as compared to models based on elemental composition. The model presented has a considerably higher correlation coefficient (0.963) and lower root mean square (0.375), mean absolute (0.328), and mean bias errors (0.010) than other models presented in the literature which, at least when applied to the present data set, tend to under-predict the combustion enthalpy. Copyright © 2017 Elsevier Ltd. All rights reserved.

  19. Probucol attenuates atrial autonomic remodeling in a canine model of atrial fibrillation produced by prolonged atrial pacing

    Institute of Scientific and Technical Information of China (English)

    GONG Yong-tai; LI Wei-min; LI Yue; YANG Shu-sen; SHENG Li; YANG Ning; SHAN Hong-bo; XUE Hong-jie; LIU Wei; YANG Bao-feng; DONG De-li; LI Bao-xin

    2009-01-01

    Background We hypothesize that increased atrial oxidative stress and inflammation may play an important role in atrial nerve sprouting and heterogeneous sympathetic hyperinnervation during atrial fibrillation (AF). To test the hypothesis, we examined whether the antioxidant and anti-inflammatory treatment with probucol attenuates atrial autonomic remodeling in a canine model of AF produced by prolonged rapid right atrial pacing. Methods Twenty-one dogs were divided into a sham-operated group, a control group and a probucol group. Dogs in the control group and probucol group underwent right atrial pacing at 400 beats per minute for 6 weeks, and those in the probucol group received probucol 1 week before rapid atrial pacing until pacing stopped. After 6-week rapid atrial pacing, general properties including left atrial structure and function, atrial hemodynamics and the inducibility and duration of AF were measured in all the groups. Atrial oxidative stress markers and serum C-reactive protein (CRP) concentration were estimated. The degree of nerve sprouting and sympathetic innervation at the right atrial anterior wall (RAAW) and the left atrial anterior wall (LAAW) were quantified by immunohistochemistry, atdal norepinephrine contents were also detected. Atrial beta-nerve growth factor (beta-NGF) mRNA and protein expression at the RAAW and LAAW were assessed by real-time quantitative RT-PCR and Western blotting respectively. Results Atrial tachypacing induced significant nerve sprouting and heterogeneous sympathetic hyperinnervation, and the magnitude of nerve sprouting and hyperinnervation was higher in the RAAW than in the LAAW. Atrial beta-NGF mRNA and protein levels were significantly increased at the RAAW and LAAW, and the upregulation of beta-NGF expression was greater at the RAAW than at the LAAW in the control group. The beta-NGF protein level was positively correlated with the density of sympathetic nerves in all groups. Probucol decreased the increase of

  20. Pattern recognition analysis and classification modeling of selenium-producing areas

    Science.gov (United States)

    Naftz, D.L.

    1996-01-01

    Established chemometric and geochemical techniques were applied to water quality data from 23 National Irrigation Water Quality Program (NIWQP) study areas in the Western United States. These techniques were applied to the NIWQP data set to identify common geochemical processes responsible for mobilization of selenium and to develop a classification model that uses major-ion concentrations to identify areas that contain elevated selenium concentrations in water that could pose a hazard to water fowl. Pattern recognition modeling of the simple-salt data computed with the SNORM geochemical program indicate three principal components that explain 95% of the total variance. A three-dimensional plot of PC 1, 2 and 3 scores shows three distinct clusters that correspond to distinct hydrochemical facies denoted as facies 1, 2 and 3. Facies 1 samples are distinguished by water samples without the CaCO3 simple salt and elevated concentrations of NaCl, CaSO4, MgSO4 and Na2SO4 simple salts relative to water samples in facies 2 and 3. Water samples in facies 2 are distinguished from facies 1 by the absence of the MgSO4 simple salt and the presence of the CaCO3 simple salt. Water samples in facies 3 are similar to samples in facies 2, with the absence of both MgSO4 and CaSO4 simple salts. Water samples in facies 1 have the largest selenium concentration (10 ??gl-1), compared to a median concentration of 2.0 ??gl-1 and less than 1.0 ??gl-1 for samples in facies 2 and 3. A classification model using the soft independent modeling by class analogy (SIMCA) algorithm was constructed with data from the NIWQP study areas. The classification model was successful in identifying water samples with a selenium concentration that is hazardous to some species of water-fowl from a test data set comprised of 2,060 water samples from throughout Utah and Wyoming. Application of chemometric and geochemical techniques during data synthesis analysis of multivariate environmental databases from other

  1. Creating Innovators through setting up organizational Vision, Mission, and Core Values : a Strategic Model in Higher Education

    OpenAIRE

    Aithal, Sreeramana

    2016-01-01

    Vision, mission, objectives and core values play major role in setting up sustainable organizations. Vision and mission statements describe the organization’s goals. Core values and core principles represent the organization’s culture. In this paper, we have discussed a model on how a higher education institution can prosper to reach its goal of ‘creating innovators’ through its vision, mission, objectives and core values. A model for the core values required for a prospective ...

  2. The Effect of using Facebook Markup Language (FBML) for Designing an E-Learning Model in Higher Education

    OpenAIRE

    Mohammed Amasha; Salem Alkhalaf

    2015-01-01

    This study examines the use of Facebook Markup Language (FBML) to design an e-learning model to facilitate teaching and learning in an academic setting. The qualitative research study presents a case study on how, Facebook is used to support collaborative activities in higher education. We used FBML to design an e-learning model called processes for e-learning resources in the Specialist Learning Resources Diploma (SLRD) program. Two groups drawn from the SLRD program were used; First were th...

  3. Modeling Coastal Erosion, Passive Inundation, and Dynamic Wave Inundation under Higher Sea Level in Hawaii

    Science.gov (United States)

    Anderson, T. R.

    2015-12-01

    Hawaii State legislators recently formed the Interagency Committee on Climate Adaptation to investigate community vulnerability to sea level rise. We developed modeling to provide the committee with assessments of exposure to coastal erosion, wave inundation, and passive flooding based on the IPCC RCP 8.5 model of sea level rise over the 21st Century. We model the exposure to coastal erosion using a hybrid equilibrium profile model (Anderson et al., 2015) that combines historical rates of shoreline change with a Bruun-type model of beach profile translation. Results are mapped in a GIS showing the 80th percentile probability of potential erosion at years 2030, 2050, 2075, and 2100. Wave inundation is modeled using XBeach. We use a 3 m significant wave height to represent a seasonal high swell event. A separate simulation was run for each heightened sea level (corresponding to the years previously mentioned); which accounts for changes in wave dynamics due to the change in water level over the reef platform. We use a bare earth topo/bathy LiDAR DEM derived from data collected during the 2013 JBLTX survey of the Hawaiian Islands. XBeach modeling is done along one-dimensional profiles spaced 20 m apart. From this, we develop a gridded product of water depth and velocity for use in a vulnerability analysis. Passive inundation due to sea level rise, the so-called "bath tub" method, provide estimates of storm drain flooding and groundwater inundation. Our analysis of these three impacts of sea level rise, combined - coastal erosion, wave inundation, and passive flooding - are used with other available data in the FEMA Hazus software to estimate exposure and loss of upland assets.

  4. Higher Resolution Modeling of the Global Terrestrial Biosphere for the PETM

    Science.gov (United States)

    Cacciatore, C.; Breecker, D.

    2015-12-01

    The Paleocene-Eocene Thermal Maximum (PETM) was a rapid climactic warming event at ~55.5 Ma associated with abrupt warming of surface temperatures (5-8 °C), massive input of carbon into the ocean-atmosphere system, and negative carbon isotope excursions (CIE) across nearly every terrestrial and oceanic carbon pool. Whereas there is ubiquitous evidence for CIEs across sites, differences in magnitude and duration of these shifts among records highlight an incomplete characterization of initial carbon injections and of ecosystem feedbacks in response to such perturbations. Numerical modeling of global carbon cycling has thus been utilized to reconcile differences between isotope records, and to also check for agreement with other constraints like carbon release scenarios and oceanic acid-base chemistry. Here, we present a carbon cycle box model that addresses oversimplification in previous quantification of terrestrial carbon cycling by introducing a soil organic and inorganic soil carbon reservoirs. The new model calculates the carbon isotope compositions of both soil organic carbon and pedogenic carbonate and considers the seasonality of calcium carbonate formation, productivity/respiration rates. Coupling this more resolved terrestrial carbon model to a global carbon flux model with established oceanic-atmospheric interaction (LOSCAR) provides a compatibility check given recent paleosol CIE records in the Bighorn Basin (Wyoming, USA). Moreover, the more highly resolved model is used in an effort to address previously irreconcilable differences between organic carbon, surface oceanic, and pedogenic CIE records. Changes in ocean and atmospheric chemistry from such rapid carbon perturbations provided in the model output ultimately serves as an important analog for modern climate change.

  5. Higher precision estimates of regional polar warming by ensemble regression of climate model projections

    Energy Technology Data Exchange (ETDEWEB)

    Bracegirdle, Thomas J. [British Antarctic Survey, Cambridge (United Kingdom); Stephenson, David B. [University of Exeter, Mathematics Research Institute, Exeter (United Kingdom); NCAS-Climate, Reading (United Kingdom)

    2012-12-15

    This study presents projections of twenty-first century wintertime surface temperature changes over the high-latitude regions based on the third Coupled Model Inter-comparison Project (CMIP3) multi-model ensemble. The state-dependence of the climate change response on the present day mean state is captured using a simple yet robust ensemble linear regression model. The ensemble regression approach gives different and more precise estimated mean responses compared to the ensemble mean approach. Over the Arctic in January, ensemble regression gives less warming than the ensemble mean along the boundary between sea ice and open ocean (sea ice edge). Most notably, the results show 3 C less warming over the Barents Sea ({proportional_to} 7 C compared to {proportional_to} 10 C). In addition, the ensemble regression method gives projections that are 30 % more precise over the Sea of Okhostk, Bering Sea and Labrador Sea. For the Antarctic in winter (July) the ensemble regression method gives 2 C more warming over the Southern Ocean close to the Greenwich Meridian ({proportional_to} 7 C compared to {proportional_to} 5 C). Projection uncertainty was almost half that of the ensemble mean uncertainty over the Southern Ocean between 30 W to 90 E and 30 % less over the northern Antarctic Peninsula. The ensemble regression model avoids the need for explicit ad hoc weighting of models and exploits the whole ensemble to objectively identify overly influential outlier models. Bootstrap resampling shows that maximum precision over the Southern Ocean can be obtained with ensembles having as few as only six climate models. (orig.)

  6. Modelling the risk of Taenia solium exposure from pork produced in western Kenya

    Science.gov (United States)

    de Glanville, William A.; Cook, Elizabeth A. J.; Bronsvoort, Barend M. De C.; Handel, Ian; Wamae, Claire N.; Kariuki, Samuel; Fèvre, Eric M.

    2017-01-01

    The tapeworm Taenia solium is the parasite responsible for neurocysticercosis, a neglected tropical disease of public health importance, thought to cause approximately 1/3 of epilepsy cases across endemic regions. The consumption of undercooked infected pork perpetuates the parasite’s life-cycle through the establishment of adult tapeworm infections in the community. Reducing the risk associated with pork consumption in the developing world is therefore a public health priority. The aim of this study was to estimate the risk of any one pork meal in western Kenya containing a potentially infective T. solium cysticercus at the point of consumption, an aspect of the parasite transmission that has not been estimated before. To estimate this, we used a quantitative food chain risk assessment model built in the @RISK add-on to Microsoft Excel. This model indicates that any one pork meal consumed in western Kenya has a 0.006 (99% Uncertainty Interval (U.I). 0.0002–0.0164) probability of containing at least one viable T. solium cysticercus at the point of consumption and therefore being potentially infectious to humans. This equates to 22,282 (99% U.I. 622–64,134) potentially infective pork meals consumed in the course of one year within Busia District alone. This model indicates a high risk of T. solium infection associated with pork consumption in western Kenya and the work presented here can be built upon to investigate the efficacy of various mitigation strategies for this locality. PMID:28212398

  7. A generative spike train model with time-structured higher order correlations

    Directory of Open Access Journals (Sweden)

    James eTrousdale

    2013-07-01

    Full Text Available Emerging technologies are revealing the spiking activity in ever larger neural ensembles. Frequently, this spiking is far from independent, with correlations in the spike times of different cells. Understanding how such correlations impact the dynamics and function of neural ensembles remains an important open problem.Here we describe a new, generative model for correlated spike trains that can exhibit many of the features observed in data. Extending prior work in mathematical finance, this generalized thinning and shift (GTaS model creates marginally Poisson spike trains with diverse temporal correlation structures.We give several examples which highlight the model's flexibility and utility. For instance, we use it to examine how a neural network responds to highly structured patterns of inputs.We then show that the GTaS model is analytically tractable, and derive cumulant densities of all orders in terms of model parameters. The GTaS framework can therefore be an important tool in the experimental and theoretical exploration of neural dynamics.

  8. On the formulations of higher-order strain gradient crystal plasticity models

    DEFF Research Database (Denmark)

    Kuroda, M.; Tvergaard, Viggo

    2008-01-01

    Recently, several higher-order extensions to the crystal plasticity theory have been proposed to incorporate effects of material length scales that were missing links in the conventional continuum mechanics. The extended theories are classified into work-conjugate and non-work-conjugate types...... backgrounds and very unlike mathematical representations. Nevertheless, both types of theories predict the same kind of material length scale effects. We have recently shown that there exists some equivalency between the two approaches in the special situation of two-dimensional single slip under small...

  9. Allocative efficiency of smallholder common bean producers in Uganda: A stochastic frontier and Tobit model approach

    Directory of Open Access Journals (Sweden)

    Sibiko, K.W.

    2013-06-01

    Full Text Available The study evaluated allocative efficiency levels of common bean farms in Eastern Uganda and the factors influencing allocative efficiencies of these farms. To achieve this objective, a sample of 480 households was randomly selected in Busia, Mbale, Budaka and Tororo districts in Eastern Uganda. Data was collected using a personally administered structured questionnaire with a focus on household decision makers; whereas a stochastic frontier model and a two limit Tobit regression model were employed in the analysis. It was established that the mean allocative efficiency was 29.37% and it was significantly influenced by farm size, off-farm income, asset value and distance to the market. Therefore the study suggested the need for policies to discourage land fragmentation and promote road and market infrastructure development in the rural areas. The study also revealed the need for farmers to be trained on entrepreneurial skills so that they can invest their farm profits into more income generating activities that will harness more farming capital.

  10. Mathematical modelling of flue gas tempered flames produced from pulverised coal fired with oxygen

    Energy Technology Data Exchange (ETDEWEB)

    Breussin, A.; Weber, R.; Kamp, W.L. van de

    1997-10-01

    The combustion of pulverised coal in conventional utility boilers contributes significantly to global CO{sub 2} emissions. Because atmospheric air is used as the combustion medium, the exhaust gases of conventional pulverised coal fired utility boilers contain approximately 15 % CO{sub 2}. This relatively low concentration makes separating and recovering CO{sub 2} a very energy-intensive process. This process can be simplified if N{sub 2} is eliminated from the comburent before combustion by firing the pulverised coal with pure oxygen. However, this concept will result in very high flames temperatures. Flue gas recirculation can be used to moderate the flame temperature, whilst generating a flue gas with a CO{sub 2} concentration of 95 %. In this presentation, both experimental and modelling work will be described. The former deals with identifying the issues related to the combustion of pulverised coal in simulated turbine exhaust gas, particularly with respect to stability, burnout and pollutant emissions. The second part of this presentation describes mathematical modelling of type 2 as well as type 1 swirling pulverised coal flames. Future work will concentrate on high CO{sub 2} levels environments. (orig.)

  11. Development of a Higher Fidelity Model for the Cascade Distillation Subsystem (CDS)

    Science.gov (United States)

    Perry, Bruce; Anderson, Molly

    2014-01-01

    Significant improvements have been made to the ACM model of the CDS, enabling accurate predictions of dynamic operations with fewer assumptions. The model has been utilized to predict how CDS performance would be impacted by changing operating parameters, revealing performance trade-offs and possibilities for improvement. CDS efficiency is driven by the THP coefficient of performance, which in turn is dependent on heat transfer within the system. Based on the remaining limitations of the simulation, priorities for further model development include: center dot Relaxing the assumption of total condensation center dot Incorporating dynamic simulation capability for the buildup of dissolved inert gasses in condensers center dot Examining CDS operation with more complex feeds center dot Extending heat transfer analysis to all surfaces

  12. LHC phenomenology and higher order electroweak corrections in supersymmetric models with and without R-parity

    Energy Technology Data Exchange (ETDEWEB)

    Liebler, Stefan Rainer

    2011-09-15

    The standard model of particle physics lacks on some shortcomings from experimental as well as from theoretical point of view: There is no approved mechanism for the generation of masses of the fundamental particles, in particular also not for the light, but massive neutrinos. In addition the standard model does not provide an explanation for the observance of dark matter in the universe. Moreover the gauge couplings of the three forces in the standard model do not unify, implying that a fundamental theory combining all forces can not be formulated. Within this thesis we address supersymmetric models as answers to these various questions, but instead of focusing on the most simple supersymmetrization of the standard model, we consider basic extensions, namely the next-to-minimal supersymmetric standard model (NMSSM), which contains an additional singlet field, and R-parity violating models. Using lepton number violating terms in the context of bilinear R-parity violation and the {mu}{nu}SSM we are able to explain neutrino physics intrinsically supersymmetric, since those terms induce a mixing between the neutralinos and the neutrinos. This thesis works out the phenomenology of the supersymmetric models under consideration and tries to point out differences to the well-known features of the simplest supersymmetric realization of the standard model. In case of the R-parity violating models the decays of the light neutralinos can result in displaced vertices. In combination with a light singlet state these displaced vertices might offer a rich phenomenology like non-standard Higgs decays into a pair of singlinos decaying with displaced vertices. Within this thesis we present some calculations at next order of perturbation theory, since one-loop corrections provide possibly large contributions to the tree-level masses and decay widths. We are using an on-shell renormalization scheme to calculate the masses of neutralinos and charginos including the neutrinos and

  13. VIRTUAL MODELING OF PHYSICAL EXPERIMENT FOR DISTANCE LEARNING SYSTEMS IN THE SECONDARY AND HIGHER PEDAGOGICAL SCHOOLS

    Directory of Open Access Journals (Sweden)

    Mykola V. Holovko

    2015-05-01

    Full Text Available The article investigates the state of the educational computer simulation and its modern features. It deals with psychological and didactic approaches to modeling in physics education and school physical experiment. It was considered the possible classification of computer models for distance learning system, as well as proposed the ways of implementing virtual experiment in distance education in physics. The main types of virtual modeling, the most widely used computer systems support in teaching physics, their possible application in teaching secondary school students were characterized. The peculiarities of distance education of future physics teachers by means of electronic teaching methods as a combination of integrated electronic educational resources and services were highlighted.

  14. Multiphysics Model of Palladium Hydride Isotope Exchange Accounting for Higher Dimensionality

    Energy Technology Data Exchange (ETDEWEB)

    Gharagozloo, Patricia E.; Eliassi, Mehdi; Bon, Bradley Luis

    2015-03-01

    This report summarizes computational model developm ent and simulations results for a series of isotope exchange dynamics experiments i ncluding long and thin isothermal beds similar to the Foltz and Melius beds and a lar ger non-isothermal experiment on the NENG7 test bed. The multiphysics 2D axi-symmetr ic model simulates the temperature and pressure dependent exchange reactio n kinetics, pressure and isotope dependent stoichiometry, heat generation from the r eaction, reacting gas flow through porous media, and non-uniformities in the bed perme ability. The new model is now able to replicate the curved reaction front and asy mmetry of the exit gas mass fractions over time. The improved understanding of the exchange process and its dependence on the non-uniform bed properties and te mperatures in these larger systems is critical to the future design of such sy stems.

  15. A self-consistent model for the evolution of the gas produced in the debris disc of β Pictoris

    Science.gov (United States)

    Kral, Q.; Wyatt, M.; Carswell, R. F.; Pringle, J. E.; Matrà, L.; Juhász, A.

    2016-09-01

    This paper presents a self-consistent model for the evolution of gas produced in the debris disc of β Pictoris. Our model proposes that atomic carbon and oxygen are created from the photodissociation of CO, which is itself released from volatile-rich bodies in the debris disc due to grain-grain collisions or photodesorption. While the CO lasts less than one orbit, the atomic gas evolves by viscous spreading resulting in an accretion disc inside the parent belt and a decretion disc outside. The temperature, ionization fraction and population levels of carbon and oxygen are followed with the photodissociation region model CLOUDY, which is coupled to a dynamical viscous α model. We present new gas observations of β Pic, of C I observed with Atacama Pathfinder EXperiment and O I observed with Herschel, and show that these along with published C II and CO observations can all be explained with this new model. Our model requires a viscosity α > 0.1, similar to that found in sufficiently ionized discs of other astronomical objects; we propose that the magnetorotational instability is at play in this highly ionized and dilute medium. This new model can be tested from its predictions for high-resolution ALMA observations of C I. We also constrain the water content of the planetesimals in β Pic. The scenario proposed here might be at play in all debris discs and this model could be used more generally on all discs with C, O or CO detections.

  16. New Models on Higher Vocational English Education and Teaching Reform:A Constructivist Perspective Based on CALL WALL

    Institute of Scientific and Technical Information of China (English)

    王艳萍; 丁宁

    2016-01-01

    Under the circumstance of higher vocational education developing rapidly and educational reform continuously deepening, esp.the variation of freshmen,the major issue of this study is to probe into new models on higher vocational English teaching reform from a constructivist perspective based on CALL WALL.The author of the article is expected to dwell on the concrete means and methods of the new models on higher vocational public English teaching reform based on students'actual situation and the author's rich teaching experience of many years by applying quantitative statistical analysis methodology of data to cultivate students'abilities of individualized self -learning and cooperative study and arouse their interest in learning English to foster their comprehensive cultural quality and meet the needs of social development in our country and international communication.

  17. Toward a Theoretical Model of Decision-Making and Resistance to Change among Higher Education Online Course Designers

    Science.gov (United States)

    Dodd, Bucky J.

    2013-01-01

    Online course design is an emerging practice in higher education, yet few theoretical models currently exist to explain or predict how the diffusion of innovations occurs in this space. This study used a descriptive, quantitative survey research design to examine theoretical relationships between decision-making style and resistance to change…

  18. Excellence in Business Education (A "FRUCE" Model for Higher Education Commission-Recognized Business Schools in Pakistan)

    Science.gov (United States)

    Kolachi, Nadir Ali; Mohammad, Jan

    2013-01-01

    The paper develops a new model of the essential factors required to be a top business school in the world for the benefit of schools recognized by the Higher Education Commission (HEC) in Pakistan. Globally, top business schools are those that excel in research, attract strong faculty, and successfully foster student development. The present…

  19. Consumer Satisfaction, Determinants, and Post-Purchase Actions in Higher Education: A Model to Guide Academic Managers.

    Science.gov (United States)

    Pate, William S.

    1993-01-01

    Applying a consumer satisfaction model to higher education program administration provides the manager with a systemic view of satisfaction, related variables, and postpurchase (alumni) actions. By manipulating the variables leading to consumer satisfaction, the institution can satisfy its consumers and increase the likelihood the consumer will…

  20. User Acceptance of Social Learning Systems in Higher Education: An Application of the Extended Technology Acceptance Model

    Science.gov (United States)

    Akman, Ibrahim; Turhan, Cigdem

    2017-01-01

    This study aims to explore the users' behaviour and acceptance of social media for learning in higher educational institutions with the help of the extended Technology Acceptance Model (TAM). TAM has been extended to investigate how ethical and security awareness of users affect the actual usage of social learning applications. For this purpose, a…