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  1. Ordinal models of audiovisual speech perception

    DEFF Research Database (Denmark)

    Andersen, Tobias

    2011-01-01

    ordinal models that can account for the McGurk illusion. We compare this type of models to the Fuzzy Logical Model of Perception (FLMP) in which the response categories are not ordered. While the FLMP generally fit the data better than the ordinal model it also employs more free parameters in complex...... experiments when the number of response categories are high as it is for speech perception in general. Testing the predictive power of the models using a form of cross-validation we found that ordinal models perform better than the FLMP. Based on these findings we suggest that ordinal models generally have...

  2. A hierarchical model for ordinal matrix factorization

    DEFF Research Database (Denmark)

    Paquet, Ulrich; Thomson, Blaise; Winther, Ole

    2012-01-01

    This paper proposes a hierarchical probabilistic model for ordinal matrix factorization. Unlike previous approaches, we model the ordinal nature of the data and take a principled approach to incorporating priors for the hidden variables. Two algorithms are presented for inference, one based...

  3. Comparison of two ordinal prediction models

    DEFF Research Database (Denmark)

    Kattan, Michael W; Gerds, Thomas A

    2015-01-01

    system (i.e. old or new), such as the level of evidence for one or more factors included in the system or the general opinions of expert clinicians. However, given the major objective of estimating prognosis on an ordinal scale, we argue that the rival staging system candidates should be compared...... on their ability to predict outcome. We sought to outline an algorithm that would compare two rival ordinal systems on their predictive ability. RESULTS: We devised an algorithm based largely on the concordance index, which is appropriate for comparing two models in their ability to rank observations. We...... demonstrate our algorithm with a prostate cancer staging system example. CONCLUSION: We have provided an algorithm for selecting the preferred staging system based on prognostic accuracy. It appears to be useful for the purpose of selecting between two ordinal prediction models....

  4. Multilevel moderated mediation model with ordinal outcome.

    Science.gov (United States)

    Rusá, Šárka; Komárek, Arnošt; Lesaffre, Emmanuel; Bruyneel, Luk

    2018-05-10

    Although increasingly complex models have been proposed in mediation literature, there is no model nor software that incorporates the multiple possible generalizations of the simple mediation model jointly. We propose a flexible moderated mediation model allowing for (1) a hierarchical structure of clustered data, (2) more and possibly correlated mediators, and (3) an ordinal outcome. The motivating data set is obtained from a European study in nursing research. Patients' willingness to recommend their treating hospital was recorded in an ordinal way. The research question is whether such recommendation directly depends on system-level features in the organization of nursing care, or whether these associations are mediated by 2 measurements of nursing care left undone and possibly moderated by nurse education. We have developed a Bayesian approach and accompanying program that takes all the above generalizations into account. Copyright © 2018 John Wiley & Sons, Ltd.

  5. An ordinal model of the McGurk illusion

    DEFF Research Database (Denmark)

    Andersen, Tobias

    2011-01-01

    an ordinal model, in which the response categories are ordered cyclically, that can account for the McGurk illusion. We compare this model to the Fuzzy Logical Model of Perception (FLMP), which is not an ordinal model, based on an original data set. While the FLMP fitted the data better than the ordinal...... model it also employed 30 free parameters where the ordinal model needed only 14. Testing the predictive power of the models using a form of cross-validation we found that, although both models performed rather poorly, the ordinal model performed better than the FLMP. Based on these findings we suggest...... that ordinal models generally have greater predictive power because they are constrained by a priori information about the adjacency of phonetic categories....

  6. MODELLING OF ORDINAL TIME SERIES BY PROPORTIONAL ODDS MODEL

    Directory of Open Access Journals (Sweden)

    Serpil AKTAŞ ALTUNAY

    2013-06-01

    Full Text Available Categorical time series data with random time dependent covariates often arise when the variable categories are assigned as categorical. There are several other models that have been proposed in the literature for the analysis of categorical time series. For example, Markov chain models, integer autoregressive processes, discrete ARMA models can be utilized for modeling of categorical time series. In general, the choice of model depends on the measurement of study variables: nominal, ordinal and interval. However, regression theory is successful approach for categorical time series which is based on generalized linear models and partial likelihood inference. One of the models for ordinal time series in regression theory is proportional odds model. In this study, proportional odds model approach to ordinal categorical time series is investigated based on a real air pollution data set and the results are discussed.

  7. Ordinal Logit and Multilevel Ordinal Logit Models: An Application on Wealth Index MICS-Survey Data

    Directory of Open Access Journals (Sweden)

    Muhammad Arfan

    2017-03-01

    Full Text Available Ordinal logistic regression models are used to predict the dependent variable, when dependent variable is of ordinal type in both the situation for single level and multilevel. The most used model for ordinal regression is the Proportional Odd (PO model which assumes that the effect of the each predictor remains same for each category of the response variable. To estimate the wealth index of household in the province Punjab the proportional odds model is used. The wealth index is an order categorical dependent variable having five categories. The data MICS (2014, a multiple indicator cluster survey conduct by Punjab bureau of statistics was used in this article. The data was recorded at different level such as individual level (household level, district level and division level. The secondary data MICS contains a sample of 41413 household collected from both rural and urban areas of the province Punjab. In the present study analysis were made for single level (household level and two levels (division level. After fitting the proportional odds model for the single level the proportionality assumption is tested by the brand test whose results suggest that all the predictors fulfill assumption of proportional odds. The significance value suggests that all the predictors have significant effect on the wealth index. The variation due to division level was estimated by two level ordinal logistic regression equal to 5.842, and the Intra Class Correlation ICC is equal to 0.6397 which show that 63.97% of total variation is due to division level.

  8. Ordinal Log-Linear Models for Contingency Tables

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    Brzezińska Justyna

    2016-12-01

    Full Text Available A log-linear analysis is a method providing a comprehensive scheme to describe the association for categorical variables in a contingency table. The log-linear model specifies how the expected counts depend on the levels of the categorical variables for these cells and provide detailed information on the associations. The aim of this paper is to present theoretical, as well as empirical, aspects of ordinal log-linear models used for contingency tables with ordinal variables. We introduce log-linear models for ordinal variables: linear-by-linear association, row effect model, column effect model and RC Goodman’s model. Algorithm, advantages and disadvantages will be discussed in the paper. An empirical analysis will be conducted with the use of R.

  9. Parameters Estimation of Geographically Weighted Ordinal Logistic Regression (GWOLR) Model

    Science.gov (United States)

    Zuhdi, Shaifudin; Retno Sari Saputro, Dewi; Widyaningsih, Purnami

    2017-06-01

    A regression model is the representation of relationship between independent variable and dependent variable. The dependent variable has categories used in the logistic regression model to calculate odds on. The logistic regression model for dependent variable has levels in the logistics regression model is ordinal. GWOLR model is an ordinal logistic regression model influenced the geographical location of the observation site. Parameters estimation in the model needed to determine the value of a population based on sample. The purpose of this research is to parameters estimation of GWOLR model using R software. Parameter estimation uses the data amount of dengue fever patients in Semarang City. Observation units used are 144 villages in Semarang City. The results of research get GWOLR model locally for each village and to know probability of number dengue fever patient categories.

  10. Comparing interval estimates for small sample ordinal CFA models.

    Science.gov (United States)

    Natesan, Prathiba

    2015-01-01

    Robust maximum likelihood (RML) and asymptotically generalized least squares (AGLS) methods have been recommended for fitting ordinal structural equation models. Studies show that some of these methods underestimate standard errors. However, these studies have not investigated the coverage and bias of interval estimates. An estimate with a reasonable standard error could still be severely biased. This can only be known by systematically investigating the interval estimates. The present study compares Bayesian, RML, and AGLS interval estimates of factor correlations in ordinal confirmatory factor analysis models (CFA) for small sample data. Six sample sizes, 3 factor correlations, and 2 factor score distributions (multivariate normal and multivariate mildly skewed) were studied. Two Bayesian prior specifications, informative and relatively less informative were studied. Undercoverage of confidence intervals and underestimation of standard errors was common in non-Bayesian methods. Underestimated standard errors may lead to inflated Type-I error rates. Non-Bayesian intervals were more positive biased than negatively biased, that is, most intervals that did not contain the true value were greater than the true value. Some non-Bayesian methods had non-converging and inadmissible solutions for small samples and non-normal data. Bayesian empirical standard error estimates for informative and relatively less informative priors were closer to the average standard errors of the estimates. The coverage of Bayesian credibility intervals was closer to what was expected with overcoverage in a few cases. Although some Bayesian credibility intervals were wider, they reflected the nature of statistical uncertainty that comes with the data (e.g., small sample). Bayesian point estimates were also more accurate than non-Bayesian estimates. The results illustrate the importance of analyzing coverage and bias of interval estimates, and how ignoring interval estimates can be misleading

  11. Fitting Multilevel Models with Ordinal Outcomes: Performance of Alternative Specifications and Methods of Estimation

    Science.gov (United States)

    Bauer, Daniel J.; Sterba, Sonya K.

    2011-01-01

    Previous research has compared methods of estimation for fitting multilevel models to binary data, but there are reasons to believe that the results will not always generalize to the ordinal case. This article thus evaluates (a) whether and when fitting multilevel linear models to ordinal outcome data is justified and (b) which estimator to employ…

  12. Time-varying effect models for ordinal responses with applications in substance abuse research.

    Science.gov (United States)

    Dziak, John J; Li, Runze; Zimmerman, Marc A; Buu, Anne

    2014-12-20

    Ordinal responses are very common in longitudinal data collected from substance abuse research or other behavioral research. This study develops a new statistical model with free SAS macros that can be applied to characterize time-varying effects on ordinal responses. Our simulation study shows that the ordinal-scale time-varying effects model has very low estimation bias and sometimes offers considerably better performance when fitting data with ordinal responses than a model that treats the response as continuous. Contrary to a common assumption that an ordinal scale with several levels can be treated as continuous, our results indicate that it is not so much the number of levels on the ordinal scale but rather the skewness of the distribution that makes a difference on relative performance of linear versus ordinal models. We use longitudinal data from a well-known study on youth at high risk for substance abuse as a motivating example to demonstrate that the proposed model can characterize the time-varying effect of negative peer influences on alcohol use in a way that is more consistent with the developmental theory and existing literature, in comparison with the linear time-varying effect model. Copyright © 2014 John Wiley & Sons, Ltd.

  13. Temperature Modelling of the Biomass Pretreatment Process

    DEFF Research Database (Denmark)

    Prunescu, Remus Mihail; Blanke, Mogens; Jensen, Jakob M.

    2012-01-01

    In a second generation biorefinery, the biomass pretreatment stage has an important contribution to the efficiency of the downstream processing units involved in biofuel production. Most of the pretreatment process occurs in a large pressurized thermal reactor that presents an irregular temperature...... distribution. Therefore, an accurate temperature model is critical for observing the biomass pretreatment. More than that, the biomass is also pushed with a constant horizontal speed along the reactor in order to ensure a continuous throughput. The goal of this paper is to derive a temperature model...... that captures the environmental temperature differences inside the reactor using distributed parameters. A Kalman filter is then added to account for any missing dynamics and the overall model is embedded into a temperature soft sensor. The operator of the plant will be able to observe the temperature in any...

  14. Sufficient Sample Size and Power in Multilevel Ordinal Logistic Regression Models

    Directory of Open Access Journals (Sweden)

    Sabz Ali

    2016-01-01

    Full Text Available For most of the time, biomedical researchers have been dealing with ordinal outcome variable in multilevel models where patients are nested in doctors. We can justifiably apply multilevel cumulative logit model, where the outcome variable represents the mild, severe, and extremely severe intensity of diseases like malaria and typhoid in the form of ordered categories. Based on our simulation conditions, Maximum Likelihood (ML method is better than Penalized Quasilikelihood (PQL method in three-category ordinal outcome variable. PQL method, however, performs equally well as ML method where five-category ordinal outcome variable is used. Further, to achieve power more than 0.80, at least 50 groups are required for both ML and PQL methods of estimation. It may be pointed out that, for five-category ordinal response variable model, the power of PQL method is slightly higher than the power of ML method.

  15. Sufficient Sample Size and Power in Multilevel Ordinal Logistic Regression Models.

    Science.gov (United States)

    Ali, Sabz; Ali, Amjad; Khan, Sajjad Ahmad; Hussain, Sundas

    2016-01-01

    For most of the time, biomedical researchers have been dealing with ordinal outcome variable in multilevel models where patients are nested in doctors. We can justifiably apply multilevel cumulative logit model, where the outcome variable represents the mild, severe, and extremely severe intensity of diseases like malaria and typhoid in the form of ordered categories. Based on our simulation conditions, Maximum Likelihood (ML) method is better than Penalized Quasilikelihood (PQL) method in three-category ordinal outcome variable. PQL method, however, performs equally well as ML method where five-category ordinal outcome variable is used. Further, to achieve power more than 0.80, at least 50 groups are required for both ML and PQL methods of estimation. It may be pointed out that, for five-category ordinal response variable model, the power of PQL method is slightly higher than the power of ML method.

  16. Ordinal regression models to describe tourist satisfaction with Sintra's world heritage

    Science.gov (United States)

    Mouriño, Helena

    2013-10-01

    In Tourism Research, ordinal regression models are becoming a very powerful tool in modelling the relationship between an ordinal response variable and a set of explanatory variables. In August and September 2010, we conducted a pioneering Tourist Survey in Sintra, Portugal. The data were obtained by face-to-face interviews at the entrances of the Palaces and Parks of Sintra. The work developed in this paper focus on two main points: tourists' perception of the entrance fees; overall level of satisfaction with this heritage site. For attaining these goals, ordinal regression models were developed. We concluded that tourist's nationality was the only significant variable to describe the perception of the admission fees. Also, Sintra's image among tourists depends not only on their nationality, but also on previous knowledge about Sintra's World Heritage status.

  17. Finite Mixture Multilevel Multidimensional Ordinal IRT Models for Large Scale Cross-Cultural Research

    Science.gov (United States)

    de Jong, Martijn G.; Steenkamp, Jan-Benedict E. M.

    2010-01-01

    We present a class of finite mixture multilevel multidimensional ordinal IRT models for large scale cross-cultural research. Our model is proposed for confirmatory research settings. Our prior for item parameters is a mixture distribution to accommodate situations where different groups of countries have different measurement operations, while…

  18. Logistic random effects regression models: A comparison of statistical packages for binary and ordinal outcomes

    NARCIS (Netherlands)

    B. Li (Bayoue); B. Roozenbeek (Bob); E.W. Steyerberg (Ewout); E.M.E.H. Lesaffre (Emmanuel)

    2011-01-01

    textabstractBackground: Logistic random effects models are a popular tool to analyze multilevel also called hierarchical data with a binary or ordinal outcome. Here, we aim to compare different statistical software implementations of these models. Methods. We used individual patient data from 8509

  19. A Composite Likelihood Inference in Latent Variable Models for Ordinal Longitudinal Responses

    Science.gov (United States)

    Vasdekis, Vassilis G. S.; Cagnone, Silvia; Moustaki, Irini

    2012-01-01

    The paper proposes a composite likelihood estimation approach that uses bivariate instead of multivariate marginal probabilities for ordinal longitudinal responses using a latent variable model. The model considers time-dependent latent variables and item-specific random effects to be accountable for the interdependencies of the multivariate…

  20. New ordinances

    International Nuclear Information System (INIS)

    Reuter, H.

    1980-01-01

    Based on extensive preliminary work of the responsible Federal Minister of Labour and Social Affairs, the 'Ordinance to Replace Ordinances under Article 24 of the Irading and Industrial Code' has been issued by the Federal Government on February 27, 1980. This new ordinance also contains the new versions of the Steam Boiler Ordinance, the Pressure Gas Ordinance, the Lift Ordinance, the Ordinance on Electrical Installations in Rooms with High Explosion Hazards, the Acetylene Ordinance, and the Ordinance on Combustible Liquids. Accordingly, these new ordinances all have the same date of issue. Coming into force on July 1, 1980, they will replace six ordinances for plants to be licensed. The same applies to the pertinent general administrative regulations. (orig.) [de

  1. Modeling thermal sensation in a Mediterranean climate—a comparison of linear and ordinal models

    Science.gov (United States)

    Pantavou, Katerina; Lykoudis, Spyridon

    2014-08-01

    A simple thermo-physiological model of outdoor thermal sensation adjusted with psychological factors is developed aiming to predict thermal sensation in Mediterranean climates. Microclimatic measurements simultaneously with interviews on personal and psychological conditions were carried out in a square, a street canyon and a coastal location of the greater urban area of Athens, Greece. Multiple linear and ordinal regression were applied in order to estimate thermal sensation making allowance for all the recorded parameters or specific, empirically selected, subsets producing so-called extensive and empirical models, respectively. Meteorological, thermo-physiological and overall models - considering psychological factors as well - were developed. Predictions were improved when personal and psychological factors were taken into account as compared to meteorological models. The model based on ordinal regression reproduced extreme values of thermal sensation vote more adequately than the linear regression one, while the empirical model produced satisfactory results in relation to the extensive model. The effects of adaptation and expectation on thermal sensation vote were introduced in the models by means of the exposure time, season and preference related to air temperature and irradiation. The assessment of thermal sensation could be a useful criterion in decision making regarding public health, outdoor spaces planning and tourism.

  2. Inferences for Joint Modelling of Repeated Ordinal Scores and Time to Event Data

    Directory of Open Access Journals (Sweden)

    Arindom Chakraborty

    2010-01-01

    Full Text Available In clinical trials and other follow-up studies, it is natural that a response variable is repeatedly measured during follow-up and the occurrence of some key event is also monitored. There has been a considerable study on the joint modelling these measures together with information on covariates. But most of the studies are related to continuous outcomes. In many situations instead of observing continuous outcomes, repeated ordinal outcomes are recorded over time. The joint modelling of such serial outcomes and the time to event data then becomes a bit complicated. In this article we have attempted to analyse such models through a latent variable model. In view of the longitudinal variation on the ordinal outcome measure, it is desirable to account for the dependence between ordered categorical responses and survival time for different causes due to unobserved factors. A flexible Monte Carlo EM (MCEM method based on exact likelihood is proposed that can simultaneously handle the longitudinal ordinal data and also the censored time to event data. A computationally more efficient MCEM method based on approximation of the likelihood is also proposed. The method is applied to a number of ordinal scores and survival data from trials of a treatment for children suffering from Duchenne Muscular Dystrophy. Finally, a simulation study is conducted to examine the finite sample properties of the proposed estimators in the joint model under two different methods.

  3. Energy consumption modeling during dairy sewage pretreatment

    Science.gov (United States)

    Dąbrowski, Wojciech; Żyłka, Radosław; Malinowski, Paweł; Boruszko, Dariusz

    2017-11-01

    The research was conducted in a dairy WWTP located in north-eastern Poland with the average flow of 546 m3d-1 and PE 11500 in 2016. Energy consumption was measured with the help of Lumel 3-phase network parameter transducers installed within the plant. The modeling was conducted based on the quantity and quality of raw sewage, after its screening, averaging and dissolved air flotation. The following parameters were determined: BOD5, COD. N-total and P-total. During the research period. 15 measurement series were carried out. Pollution loads removed in primary treatment varied from 167.0 to 803.5 kgO2d-1 and 1205.9 to 10032 kgO2d-1 for BOD5 and COD respectively. The energy consumption share during dairy pretreatment in relation to the total energy consumption was in the range from 13.8 to 28.5% with the mean value of 18.7% during the research period. Energy consumption indicators relating to removed pollution loads for primary treatment were established with the mean values of 0.74 and 0.83 kWhkg-1d-1 for BOD5 and COD respectively. An attempt was made to determine the influence of raw sewage characteristics and pretreatment efficiency on energy consumption of the object. A model of energy consumption during pretreatment was estimated according to the experimental data obtained in the research period. It was modeled using the linear regression model and principal component analysis.

  4. Energy consumption modeling during dairy sewage pretreatment

    Directory of Open Access Journals (Sweden)

    Dąbrowski Wojciech

    2017-01-01

    Full Text Available The research was conducted in a dairy WWTP located in north-eastern Poland with the average flow of 546 m3d-1 and PE 11500 in 2016. Energy consumption was measured with the help of Lumel 3-phase network parameter transducers installed within the plant. The modeling was conducted based on the quantity and quality of raw sewage, after its screening, averaging and dissolved air flotation. The following parameters were determined: BOD5, COD. N-total and P-total. During the research period. 15 measurement series were carried out. Pollution loads removed in primary treatment varied from 167.0 to 803.5 kgO2d-1 and 1205.9 to 10032 kgO2d-1 for BOD5 and COD respectively. The energy consumption share during dairy pretreatment in relation to the total energy consumption was in the range from 13.8 to 28.5% with the mean value of 18.7% during the research period. Energy consumption indicators relating to removed pollution loads for primary treatment were established with the mean values of 0.74 and 0.83 kWhkg-1d-1 for BOD5 and COD respectively. An attempt was made to determine the influence of raw sewage characteristics and pretreatment efficiency on energy consumption of the object. A model of energy consumption during pretreatment was estimated according to the experimental data obtained in the research period. It was modeled using the linear regression model and principal component analysis.

  5. A New Statistic for Evaluating Item Response Theory Models for Ordinal Data. CRESST Report 839

    Science.gov (United States)

    Cai, Li; Monroe, Scott

    2014-01-01

    We propose a new limited-information goodness of fit test statistic C[subscript 2] for ordinal IRT models. The construction of the new statistic lies formally between the M[subscript 2] statistic of Maydeu-Olivares and Joe (2006), which utilizes first and second order marginal probabilities, and the M*[subscript 2] statistic of Cai and Hansen…

  6. A Random Pattern Mixture Model for Ordinal Outcomes with Informative Dropouts

    Science.gov (United States)

    Liu, Chengcheng; Ratcliffe, Sarah J.; Guo, Wensheng

    2016-01-01

    We extend a random pattern mixture joint model for longitudinal ordinal outcomes and informative dropouts. The patients are generalized to ”pattern” groups based on known covariates that are potential surrogated for the severity of the underlying condition. The random pattern effects are defined as the latent effects linking the dropout process and the ordinal longitudinal outcome. Conditional on the random pattern effects, the longitudinal outcome and the dropout times are assumed independent. Estimates are obtained via the EM algorithm. We applied the model to the end-stage renal disease (ESRD) data. Anemia was found to be significantly affected by baseline iron treatment when the dropout information was adjusted via the study model; as opposed to an independent or shared parameter model. Simulations were performed to evaluate the performance of the random pattern mixture model under various assumptions. PMID:25894456

  7. An efficient hierarchical generalized linear mixed model for mapping QTL of ordinal traits in crop cultivars.

    Science.gov (United States)

    Feng, Jian-Ying; Zhang, Jin; Zhang, Wen-Jie; Wang, Shi-Bo; Han, Shi-Feng; Zhang, Yuan-Ming

    2013-01-01

    Many important phenotypic traits in plants are ordinal. However, relatively little is known about the methodologies for ordinal trait association studies. In this study, we proposed a hierarchical generalized linear mixed model for mapping quantitative trait locus (QTL) of ordinal traits in crop cultivars. In this model, all the main-effect QTL and QTL-by-environment interaction were treated as random, while population mean, environmental effect and population structure were fixed. In the estimation of parameters, the pseudo data normal approximation of likelihood function and empirical Bayes approach were adopted. A series of Monte Carlo simulation experiments were performed to confirm the reliability of new method. The result showed that new method works well with satisfactory statistical power and precision. The new method was also adopted to dissect the genetic basis of soybean alkaline-salt tolerance in 257 soybean cultivars obtained, by stratified random sampling, from 6 geographic ecotypes in China. As a result, 6 main-effect QTL and 3 QTL-by-environment interactions were identified.

  8. Assessing Heterogeneity for Factor Analysis Model with Continuous and Ordinal Outcomes

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    Ye-Mao Xia

    2016-01-01

    Full Text Available Factor analysis models with continuous and ordinal responses are a useful tool for assessing relations between the latent variables and mixed observed responses. These models have been successfully applied to many different fields, including behavioral, educational, and social-psychological sciences. However, within the Bayesian analysis framework, most developments are constrained within parametric families, of which the particular distributions are specified for the parameters of interest. This leads to difficulty in dealing with outliers and/or distribution deviations. In this paper, we propose a Bayesian semiparametric modeling for factor analysis model with continuous and ordinal variables. A truncated stick-breaking prior is used to model the distributions of the intercept and/or covariance structural parameters. Bayesian posterior analysis is carried out through the simulation-based method. Blocked Gibbs sampler is implemented to draw observations from the complicated posterior. For model selection, the logarithm of pseudomarginal likelihood is developed to compare the competing models. Empirical results are presented to illustrate the application of the methodology.

  9. Autoregressive transitional ordinal model to test for treatment effect in neurological trials with complex endpoints

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    Lorenzo G. Tanadini

    2016-11-01

    Full Text Available Abstract Background A number of potential therapeutic approaches for neurological disorders have failed to provide convincing evidence of efficacy, prompting pharmaceutical and health companies to discontinue their involvement in drug development. Limitations in the statistical analysis of complex endpoints have very likely had a negative impact on the translational process. Methods We propose a transitional ordinal model with an autoregressive component to overcome previous limitations in the analysis of Upper Extremity Motor Scores, a relevant endpoint in the field of Spinal Cord Injury. Statistical power and clinical interpretation of estimated treatment effects of the proposed model were compared to routinely employed approaches in a large simulation study of two-arm randomized clinical trials. A revisitation of a key historical trial provides further comparison between the different analysis approaches. Results The proposed model outperformed all other approaches in virtually all simulation settings, achieving on average 14 % higher statistical power than the respective second-best performing approach (range: -1 %, +34 %. Only the transitional model allows treatment effect estimates to be interpreted as conditional odds ratios, providing clear interpretation and visualization. Conclusion The proposed model takes into account the complex ordinal nature of the endpoint under investigation and explicitly accounts for relevant prognostic factors such as lesion level and baseline information. Superior statistical power, combined with clear clinical interpretation of estimated treatment effects and widespread availability in commercial software, are strong arguments for clinicians and trial scientists to adopt, and further extend, the proposed approach.

  10. Logistic random effects regression models: a comparison of statistical packages for binary and ordinal outcomes.

    Science.gov (United States)

    Li, Baoyue; Lingsma, Hester F; Steyerberg, Ewout W; Lesaffre, Emmanuel

    2011-05-23

    Logistic random effects models are a popular tool to analyze multilevel also called hierarchical data with a binary or ordinal outcome. Here, we aim to compare different statistical software implementations of these models. We used individual patient data from 8509 patients in 231 centers with moderate and severe Traumatic Brain Injury (TBI) enrolled in eight Randomized Controlled Trials (RCTs) and three observational studies. We fitted logistic random effects regression models with the 5-point Glasgow Outcome Scale (GOS) as outcome, both dichotomized as well as ordinal, with center and/or trial as random effects, and as covariates age, motor score, pupil reactivity or trial. We then compared the implementations of frequentist and Bayesian methods to estimate the fixed and random effects. Frequentist approaches included R (lme4), Stata (GLLAMM), SAS (GLIMMIX and NLMIXED), MLwiN ([R]IGLS) and MIXOR, Bayesian approaches included WinBUGS, MLwiN (MCMC), R package MCMCglmm and SAS experimental procedure MCMC.Three data sets (the full data set and two sub-datasets) were analysed using basically two logistic random effects models with either one random effect for the center or two random effects for center and trial. For the ordinal outcome in the full data set also a proportional odds model with a random center effect was fitted. The packages gave similar parameter estimates for both the fixed and random effects and for the binary (and ordinal) models for the main study and when based on a relatively large number of level-1 (patient level) data compared to the number of level-2 (hospital level) data. However, when based on relatively sparse data set, i.e. when the numbers of level-1 and level-2 data units were about the same, the frequentist and Bayesian approaches showed somewhat different results. The software implementations differ considerably in flexibility, computation time, and usability. There are also differences in the availability of additional tools for model

  11. Logistic random effects regression models: a comparison of statistical packages for binary and ordinal outcomes

    Directory of Open Access Journals (Sweden)

    Steyerberg Ewout W

    2011-05-01

    Full Text Available Abstract Background Logistic random effects models are a popular tool to analyze multilevel also called hierarchical data with a binary or ordinal outcome. Here, we aim to compare different statistical software implementations of these models. Methods We used individual patient data from 8509 patients in 231 centers with moderate and severe Traumatic Brain Injury (TBI enrolled in eight Randomized Controlled Trials (RCTs and three observational studies. We fitted logistic random effects regression models with the 5-point Glasgow Outcome Scale (GOS as outcome, both dichotomized as well as ordinal, with center and/or trial as random effects, and as covariates age, motor score, pupil reactivity or trial. We then compared the implementations of frequentist and Bayesian methods to estimate the fixed and random effects. Frequentist approaches included R (lme4, Stata (GLLAMM, SAS (GLIMMIX and NLMIXED, MLwiN ([R]IGLS and MIXOR, Bayesian approaches included WinBUGS, MLwiN (MCMC, R package MCMCglmm and SAS experimental procedure MCMC. Three data sets (the full data set and two sub-datasets were analysed using basically two logistic random effects models with either one random effect for the center or two random effects for center and trial. For the ordinal outcome in the full data set also a proportional odds model with a random center effect was fitted. Results The packages gave similar parameter estimates for both the fixed and random effects and for the binary (and ordinal models for the main study and when based on a relatively large number of level-1 (patient level data compared to the number of level-2 (hospital level data. However, when based on relatively sparse data set, i.e. when the numbers of level-1 and level-2 data units were about the same, the frequentist and Bayesian approaches showed somewhat different results. The software implementations differ considerably in flexibility, computation time, and usability. There are also differences in

  12. Fisher Scoring Method for Parameter Estimation of Geographically Weighted Ordinal Logistic Regression (GWOLR) Model

    Science.gov (United States)

    Widyaningsih, Purnami; Retno Sari Saputro, Dewi; Nugrahani Putri, Aulia

    2017-06-01

    GWOLR model combines geographically weighted regression (GWR) and (ordinal logistic reression) OLR models. Its parameter estimation employs maximum likelihood estimation. Such parameter estimation, however, yields difficult-to-solve system of nonlinear equations, and therefore numerical approximation approach is required. The iterative approximation approach, in general, uses Newton-Raphson (NR) method. The NR method has a disadvantage—its Hessian matrix is always the second derivatives of each iteration so it does not always produce converging results. With regard to this matter, NR model is modified by substituting its Hessian matrix into Fisher information matrix, which is termed Fisher scoring (FS). The present research seeks to determine GWOLR model parameter estimation using Fisher scoring method and apply the estimation on data of the level of vulnerability to Dengue Hemorrhagic Fever (DHF) in Semarang. The research concludes that health facilities give the greatest contribution to the probability of the number of DHF sufferers in both villages. Based on the number of the sufferers, IR category of DHF in both villages can be determined.

  13. An ordinal approach to computing with words and the preference-aversion model

    DEFF Research Database (Denmark)

    Franco de los Rios, Camilo Andres; Rodríguez, J. Tinguaro; Montero, Javier

    2014-01-01

    Computing with words (CWW) explores the brain’s ability to handle and evaluate perceptions through language, i.e., by means of the linguistic representation of information and knowledge. On the other hand, standard preference structures examine decision problems through the decomposition of the p......Computing with words (CWW) explores the brain’s ability to handle and evaluate perceptions through language, i.e., by means of the linguistic representation of information and knowledge. On the other hand, standard preference structures examine decision problems through the decomposition...... of the preference predicate into the simpler situations of strict preference, indifference and incomparability. Hence, following the distinctive cognitive/neurological features for perceiving positive and negative stimuli in separate regions of the brain, we consider two separate and opposite poles of preference...... and aversion, and obtain an extended preference structure named the Preference–aversion (P–A) structure. In this way, examining the meaning of words under an ordinal scale and using CWW’s methodology, we are able to formulate the P–A model under a simple and purely linguistic approach to decision making...

  14. Ordinal Bivariate Inequality

    DEFF Research Database (Denmark)

    Sonne-Schmidt, Christoffer Scavenius; Tarp, Finn; Østerdal, Lars Peter Raahave

    2016-01-01

    This paper introduces a concept of inequality comparisons with ordinal bivariate categorical data. In our model, one population is more unequal than another when they have common arithmetic median outcomes and the first can be obtained from the second by correlation-increasing switches and....../or median-preserving spreads. For the canonical 2 × 2 case (with two binary indicators), we derive a simple operational procedure for checking ordinal inequality relations in practice. As an illustration, we apply the model to childhood deprivation in Mozambique....

  15. Ordinal bivariate inequality

    DEFF Research Database (Denmark)

    Sonne-Schmidt, Christoffer Scavenius; Tarp, Finn; Østerdal, Lars Peter Raahave

    This paper introduces a concept of inequality comparisons with ordinal bivariate categorical data. In our model, one population is more unequal than another when they have common arithmetic median outcomes and the first can be obtained from the second by correlationincreasing switches and/or median......-preserving spreads. For the canonical 2x2 case (with two binary indicators), we derive a simple operational procedure for checking ordinal inequality relations in practice. As an illustration, we apply the model to childhood deprivation in Mozambique....

  16. Semiparametric Multinomial Ordinal Model to Analyze Spatial Patterns of Child Birth Weight in Nigeria

    Directory of Open Access Journals (Sweden)

    Rasheed A. Adeyemi

    2016-11-01

    Full Text Available Background: Birth weight is an important health parameter for obstetricians and gynaecologists. It is a good health indicator of a child-bearing mother and a strong predictor of infant morbidity and mortality. Methods: This paper utilizes data on 28,647 children born between 2003–2008 obtained from the 2008 Nigeria Demographic and Health Survey (NDHS. For a simple epidemiological convenience, the occurrence of a newborn weight can intuitively be considered to be categorical in nature and the thresholds can be put on a continuous scale. In survey reporting, the mothers frequently estimate their infant’s birth weight and make a classification in ordinal category (low, normal, large instead of actual birth weight. The study fits a multinomial regression model to analyze the relationships between the polytomous response and different kind of covariates in a unified manner. We estimate the fixed effects of bio-social covariates parametrically and the non-linear effect modeled using P-spline. The spatial component was modeled using conditional autoregressive error. A penalized maximum likelihood estimation was performed to estimate the model parameters. Results: We found risk factors that are positively associated with low birth weight, which include multiple birth, short birth interval, death of sibling, childhood diarrhea, fever, mother’s smoking, firewood/dung cooking and poor household. Results further showed that iron syrup supplementation, antenatal attendance, mother literacy and household wealth had significant association with low probability of low birth weight. The finding also showed spatial patterns, which are not captured by the underlying determinants, and we produced probability predictive maps of the spatial residual effects. Conclusions: In addition to the statistical relevance of our method, the generated spatial maps identify highly endemic areas of low birth weight that can assist government agency to channel scarce health

  17. An analytical discrete-ordinates solution for an improved one-dimensional model of three-dimensional transport in ducts

    International Nuclear Information System (INIS)

    Garcia, R.D.M.

    2015-01-01

    Highlights: • An improved 1-D model of 3-D particle transport in ducts is studied. • The cases of isotropic and directional incidence are treated with the ADO method. • Accurate numerical results are reported for ducts of circular cross section. • A comparison with results of other authors is included. • The ADO method is found to be very efficient. - Abstract: An analytical discrete-ordinates solution is developed for the problem of particle transport in ducts, as described by a one-dimensional model constructed with two basis functions. Two types of particle incidence are considered: isotropic incidence and incidence described by the Dirac delta distribution. Accurate numerical results are tabulated for the reflection probabilities of semi-infinite ducts and the reflection and transmission probabilities of finite ducts. It is concluded that the developed solution is more efficient than commonly used numerical implementations of the discrete-ordinates method.

  18. Intercomparison and biokinetic model validation of radionuclide intake assessment. Report of a co-ordinated research project. 1996-1998

    International Nuclear Information System (INIS)

    1999-03-01

    This TECDOC presents the results of a Co-ordinated Research Project (CRP) on Intercomparison and Biokinetic Model Validation of Radionuclide Intake Assessment, including the conclusions of a Research Co-ordination Meeting held from 6 to 8 July 1998. The present CRP on Intercomparison and Biokinetic Model Validation of Radionuclide Intake Assessment is part of the activities of the IAEA's Occupational Protection programme. The objective of this programme is to promote an internationally harmonized approach for optimizing occupational radiation protection through: the development of guides, within the IAEA's activities for establishing standards for radiation protection, for restricting radiation exposures in the workplace and for applying current occupational radiation protection techniques; and the promotion of application of these guidelines

  19. A Bayesian ordinal logistic regression model to correct for interobserver measurement error in a geographical oral health study

    OpenAIRE

    LESAFFRE, Emmanuel; Mwalili, Samuel M.; Declerck, Dominique

    2005-01-01

    We present an approach for correcting for interobserver measurement error in an ordinal logistic regression model taking into account also the variability of the estimated correction terms. The different scoring behaviour of the 16 examiners complicated the identification of a geographical trend in a recent study on caries experience in Flemish children (Belgium) who were 7 years old. Since the measurement error is on the response the factor 'examiner' could be included in the regression mode...

  20. Description of waste pretreatment and interfacing systems dynamic simulation model

    Energy Technology Data Exchange (ETDEWEB)

    Garbrick, D.J.; Zimmerman, B.D.

    1995-05-01

    The Waste Pretreatment and Interfacing Systems Dynamic Simulation Model was created to investigate the required pretreatment facility processing rates for both high level and low level waste so that the vitrification of tank waste can be completed according to the milestones defined in the Tri-Party Agreement (TPA). In order to achieve this objective, the processes upstream and downstream of the pretreatment facilities must also be included. The simulation model starts with retrieval of tank waste and ends with vitrification for both low level and high level wastes. This report describes the results of three simulation cases: one based on suggested average facility processing rates, one with facility rates determined so that approximately 6 new DSTs are required, and one with facility rates determined so that approximately no new DSTs are required. It appears, based on the simulation results, that reasonable facility processing rates can be selected so that no new DSTs are required by the TWRS program. However, this conclusion must be viewed with respect to the modeling assumptions, described in detail in the report. Also included in the report, in an appendix, are results of two sensitivity cases: one with glass plant water recycle steams recycled versus not recycled, and one employing the TPA SST retrieval schedule versus a more uniform SST retrieval schedule. Both recycling and retrieval schedule appear to have a significant impact on overall tank usage.

  1. Reconsidering the use of rankings in the valuation of health states: a model for estimating cardinal values from ordinal data

    Directory of Open Access Journals (Sweden)

    Salomon Joshua A

    2003-12-01

    Full Text Available Abstract Background In survey studies on health-state valuations, ordinal ranking exercises often are used as precursors to other elicitation methods such as the time trade-off (TTO or standard gamble, but the ranking data have not been used in deriving cardinal valuations. This study reconsiders the role of ordinal ranks in valuing health and introduces a new approach to estimate interval-scaled valuations based on aggregate ranking data. Methods Analyses were undertaken on data from a previously published general population survey study in the United Kingdom that included rankings and TTO values for hypothetical states described using the EQ-5D classification system. The EQ-5D includes five domains (mobility, self-care, usual activities, pain/discomfort and anxiety/depression with three possible levels on each. Rank data were analysed using a random utility model, operationalized through conditional logit regression. In the statistical model, probabilities of observed rankings were related to the latent utilities of different health states, modeled as a linear function of EQ-5D domain scores, as in previously reported EQ-5D valuation functions. Predicted valuations based on the conditional logit model were compared to observed TTO values for the 42 states in the study and to predictions based on a model estimated directly from the TTO values. Models were evaluated using the intraclass correlation coefficient (ICC between predictions and mean observations, and the root mean squared error of predictions at the individual level. Results Agreement between predicted valuations from the rank model and observed TTO values was very high, with an ICC of 0.97, only marginally lower than for predictions based on the model estimated directly from TTO values (ICC = 0.99. Individual-level errors were also comparable in the two models, with root mean squared errors of 0.503 and 0.496 for the rank-based and TTO-based predictions, respectively. Conclusions

  2. Modeling of pretreatment condition of extrusion-pretreated prairie cordgrass and corn stover with poly (oxyethylen)20 sorbitan monolaurate.

    Science.gov (United States)

    Eckard, Anahita Dehkhoda; Muthukumarappan, Kasiviswanathan; Gibbons, William

    2012-05-01

    Extrusion processing has shown potential to be used as a pretreatment method for second-generation bioethanol production. Furthermore, surfactants have been shown to reduce enzyme deactivation and increase the efficiency of hydrolysis. Therefore, a sequential pretreatment technique was developed for corn stover (CS) and prairie cordgrass (PCG) in which a single screw extruder was used for the first pretreatment according to a previously optimized condition using 70-180 °C for feed, barrel, and die zones with 65-155 rpm screw speed. The second pretreatment was optimized in this study at 45-55 °C, 1-4 h, 0.15-0.6 g Tween 20/g glucan according to response surface methodology. Optimization of surfactant pretreatment facilitated the estimation of interaction and higher-order effects for major factors involved in surfactant treatment (temperature, time, surfactant loading). Using 8.6 FPU/g glucan cellulase, the optimum conditions found by fitting appropriate quadratic models to the data increased glucose and xylose yield by 27.5 and 33% for CS and by 21.5 and 27% for PCG, respectively. Tween 20 concentrations and pretreatment temperature were the most significant factors affecting sugar yield (p value <0.05). Studies of SDS concentration at and beyond critical micelle concentration (5.2-100 mM) demonstrated a decrease in sugar yield compared to control.

  3. A new parsimonious model for ordinal longitudinal data with application to subjective evaluations of a gastrointestinal disease.

    Science.gov (United States)

    Ursino, Moreno; Gasparini, Mauro

    2018-05-01

    In this paper, a new discrete statistical model for ordered categorical data is proposed via fixed-point discretization of a beta latent variable. The resulting discretized beta distribution has a highly flexible shape and it can be either over-dispersed or under-dispersed with respect to the binomial distribution. It has only two parameters, which may therefore parsimoniously depend on covariates and on random effects, providing new tools for the analysis of structured, clustered or longitudinal ordinal data. Practical examples and advices are given and an application of the new model to subjective evaluations of a gastrointestinal disease is shown.

  4. Regression modeling strategies with applications to linear models, logistic and ordinal regression, and survival analysis

    CERN Document Server

    Harrell , Jr , Frank E

    2015-01-01

    This highly anticipated second edition features new chapters and sections, 225 new references, and comprehensive R software. In keeping with the previous edition, this book is about the art and science of data analysis and predictive modeling, which entails choosing and using multiple tools. Instead of presenting isolated techniques, this text emphasizes problem solving strategies that address the many issues arising when developing multivariable models using real data and not standard textbook examples. It includes imputation methods for dealing with missing data effectively, methods for fitting nonlinear relationships and for making the estimation of transformations a formal part of the modeling process, methods for dealing with "too many variables to analyze and not enough observations," and powerful model validation techniques based on the bootstrap.  The reader will gain a keen understanding of predictive accuracy, and the harm of categorizing continuous predictors or outcomes.  This text realistically...

  5. R programming for parameters estimation of geographically weighted ordinal logistic regression (GWOLR) model based on Newton Raphson

    Science.gov (United States)

    Zuhdi, Shaifudin; Saputro, Dewi Retno Sari

    2017-03-01

    GWOLR model used for represent relationship between dependent variable has categories and scale of category is ordinal with independent variable influenced the geographical location of the observation site. Parameters estimation of GWOLR model use maximum likelihood provide system of nonlinear equations and hard to be found the result in analytic resolution. By finishing it, it means determine the maximum completion, this thing associated with optimizing problem. The completion nonlinear system of equations optimize use numerical approximation, which one is Newton Raphson method. The purpose of this research is to make iteration algorithm Newton Raphson and program using R software to estimate GWOLR model. Based on the research obtained that program in R can be used to estimate the parameters of GWOLR model by forming a syntax program with command "while".

  6. [Ordinal logistic regression in epidemiological studies].

    Science.gov (United States)

    Abreu, Mery Natali Silva; Siqueira, Arminda Lucia; Caiaffa, Waleska Teixeira

    2009-02-01

    Ordinal logistic regression models have been developed for analysis of epidemiological studies. However, the adequacy of such models for adjustment has so far received little attention. In this article, we reviewed the most important ordinal regression models and common approaches used to verify goodness-of-fit, using R or Stata programs. We performed formal and graphical analyses to compare ordinal models using data sets on health conditions from the National Health and Nutrition Examination Survey (NHANES II).

  7. The impact of tourists on Antarctic tardigrades: an ordination-based model

    Directory of Open Access Journals (Sweden)

    Sandra J. McInnes

    2013-05-01

    Full Text Available Tardigrades are important members of the Antarctic biota yet little is known about their role in the soil fauna or whether they are affected by anthropogenic factors. The German Federal Environment Agency commissioned research to assess the impact of human activities on soil meiofauna at 14 localities along the Antarctic peninsula during the 2009/2010 and 2010/2011 austral summers. We used ordination techniques to re-assess the block-sampling design used to compare areas of high and low human impact, to identify which of the sampled variables were biologically relevant and/or demonstrated an anthropogenic significance. We found the most significant differences between locations, reflecting local habitat and vegetation factor, rather than within-location anthropogenic impact. We noted no evidence of exotic imports but report on new maritime Antarctic sample sites and habitats.

  8. Prediction of two month modified Rankin Scale with an ordinal prediction model in patients with aneurysmal subarachnoid haemorrhage

    Directory of Open Access Journals (Sweden)

    Sneade Mary

    2010-09-01

    Full Text Available Abstract Background Aneurysmal subarachnoid haemorrhage (aSAH is a devastating event with a frequently disabling outcome. Our aim was to develop a prognostic model to predict an ordinal clinical outcome at two months in patients with aSAH. Methods We studied patients enrolled in the International Subarachnoid Aneurysm Trial (ISAT, a randomized multicentre trial to compare coiling and clipping in aSAH patients. Several models were explored to estimate a patient's outcome according to the modified Rankin Scale (mRS at two months after aSAH. Our final model was validated internally with bootstrapping techniques. Results The study population comprised of 2,128 patients of whom 159 patients died within 2 months (8%. Multivariable proportional odds analysis identified World Federation of Neurosurgical Societies (WFNS grade as the most important predictor, followed by age, sex, lumen size of the aneurysm, Fisher grade, vasospasm on angiography, and treatment modality. The model discriminated moderately between those with poor and good mRS scores (c statistic = 0.65, with minor optimism according to bootstrap re-sampling (optimism corrected c statistic = 0.64. Conclusion We presented a calibrated and internally validated ordinal prognostic model to predict two month mRS in aSAH patients who survived the early stage up till a treatment decision. Although generalizability of the model is limited due to the selected population in which it was developed, this model could eventually be used to support clinical decision making after external validation. Trial Registration International Standard Randomised Controlled Trial, Number ISRCTN49866681

  9. Nested generalized linear mixed model with ordinal response: Simulation and application on poverty data in Java Island

    Science.gov (United States)

    Widyaningsih, Yekti; Saefuddin, Asep; Notodiputro, Khairil A.; Wigena, Aji H.

    2012-05-01

    The objective of this research is to build a nested generalized linear mixed model using an ordinal response variable with some covariates. There are three main jobs in this paper, i.e. parameters estimation procedure, simulation, and implementation of the model for the real data. At the part of parameters estimation procedure, concepts of threshold, nested random effect, and computational algorithm are described. The simulations data are built for 3 conditions to know the effect of different parameter values of random effect distributions. The last job is the implementation of the model for the data about poverty in 9 districts of Java Island. The districts are Kuningan, Karawang, and Majalengka chose randomly in West Java; Temanggung, Boyolali, and Cilacap from Central Java; and Blitar, Ngawi, and Jember from East Java. The covariates in this model are province, number of bad nutrition cases, number of farmer families, and number of health personnel. In this modeling, all covariates are grouped as ordinal scale. Unit observation in this research is sub-district (kecamatan) nested in district, and districts (kabupaten) are nested in province. For the result of simulation, ARB (Absolute Relative Bias) and RRMSE (Relative Root of mean square errors) scale is used. They show that prov parameters have the highest bias, but more stable RRMSE in all conditions. The simulation design needs to be improved by adding other condition, such as higher correlation between covariates. Furthermore, as the result of the model implementation for the data, only number of farmer family and number of medical personnel have significant contributions to the level of poverty in Central Java and East Java province, and only district 2 (Karawang) of province 1 (West Java) has different random effect from the others. The source of the data is PODES (Potensi Desa) 2008 from BPS (Badan Pusat Statistik).

  10. Modelling post-fire soil erosion hazard using ordinal logistic regression: A case study in South-eastern Spain

    Science.gov (United States)

    Notario del Pino, Jesús S.; Ruiz-Gallardo, José-Reyes

    2015-03-01

    Treatments that minimize soil erosion after large wildfires depend, among other factors, on fire severity and landscape configuration so that, in practice, most of them are applied according to emergency criteria. Therefore, simple tools to predict soil erosion risk help to decide where the available resources should be used first. In this study, a predictive model for soil erosion degree, based on ordinal logistic regression, has been developed and evaluated using data from three large forest fires in South-eastern Spain. The field data were successfully fit to the model in 60% of cases after 50 runs (i.e., agreement between observed and predicted soil erosion degrees), using slope steepness, slope aspect, and fire severity as predictors. North-facing slopes were shown to be less prone to soil erosion than the rest.

  11. GEEORD: A SAS macro for analyzing ordinal response variables with repeated measures through proportional odds, partial proportional odds, or non-proportional odds models.

    Science.gov (United States)

    Gao, Xiaoming; Schwartz, Todd A; Preisser, John S; Perin, Jamie

    2017-10-01

    A SAS macro, GEEORD, has been developed for the analysis of ordinal responses with repeated measures through a regression model that flexibly allows the proportional odds assumption to apply (or not) separately for each explanatory variable. Previously utilized in an analysis of a longitudinal orthognathic surgery clinical trial by Preisser et al. [1,2], the basis of GEEORD is the generalized estimating equations (GEE) method for cumulative logits models described by Lipsitz et al. [3]. The macro extends the capabilities for modeling correlated ordinal data of GEECAT, a SAS macro that allows the user to model correlated categorical response data [4]. The macro applies to independent ordinal responses as a special case. Examples are provided to demonstrate the convenient application of GEEORD to two different datasets. The macro's features are illustrated in fitting models to ordinal response variables in univariate and repeated measures settings; this includes the capacity to fit the non-proportional odds model, the partial proportional odds model, and the proportional odds model. The macro additionally provides relevant tests of the proportional odds assumption. Copyright © 2017 Elsevier B.V. All rights reserved.

  12. Computational Modeling of a Time-Independent, Heterogeneous Reactor Core Using Simplified Discrete Ordinates Neutron Transport Techniques

    National Research Council Canada - National Science Library

    Labowski, Kristofer

    2001-01-01

    The Linear Characteristic (LC) method on rectangular boxoid meshes is a discrete ordinate neutron transport technique that uses both zeroth and first moments of the angular neutron flux to construct a relatively accurate...

  13. Neutronics analysis of the International Thermonuclear Experimental Reactor (ITER) MCNP ''Benchmark CAD Model'' with the ATTILA discrete ordinance code

    International Nuclear Information System (INIS)

    Youssef, M.Z.; Feder, R.; Davis, I.

    2007-01-01

    The ITER IT has adopted the newly developed FEM, 3-D, and CAD-based Discrete Ordinates code, ATTILA for the neutronics studies contingent on its success in predicting key neutronics parameters and nuclear field according to the stringent QA requirements set forth by the Management and Quality Program (MQP). ATTILA has the advantage of providing a full flux and response functions mapping everywhere in one run where components subjected to excessive radiation level and strong streaming paths can be identified. The ITER neutronics community had agreed to use a standard CAD model of ITER (40 degree sector, denoted ''Benchmark CAD Model'') to compare results for several responses selected for calculation benchmarking purposes to test the efficiency and accuracy of the CAD-MCNP approach developed by each party. Since ATTILA seems to lend itself as a powerful design tool with minimal turnaround time, it was decided to benchmark this model with ATTILA as well and compare the results to those obtained with the CAD MCNP calculations. In this paper we report such comparison for five responses, namely: (1) Neutron wall load on the surface of the 18 shield blanket module (SBM), (2) Neutron flux and nuclear heating rate in the divertor cassette, (3) nuclear heating rate in the winding pack of the inner leg of the TF coil, (4) Radial flux profile across dummy port plug and shield plug placed in the equatorial port, and (5) Flux at seven point locations situated behind the equatorial port plug. (orig.)

  14. Ordinal Comparison of Multidimensional Deprivation

    DEFF Research Database (Denmark)

    Sonne-Schmidt, Christoffer Scavenius; Tarp, Finn; Østerdal, Lars Peter

    This paper develops an ordinal method of comparison of multidimensional inequality. In our model, population distribution g is more unequal than f when the distributions have common median and can be obtained from f  by one or more shifts in population density that increase inequality. For our...

  15. Second Ordinance amending the Radiation Protection Ordinance

    International Nuclear Information System (INIS)

    1989-01-01

    The amendment of the Radiation Protection Ordinance brings about the following changes: (1) Introduction of the concept of effective dose, reduction of limits for partial body dose, adoption of the radiotoxicity values of radionuclides as established by the EC Basis Standards; (2) introduction of a working-life-related dose limit of 400 mSv; (3) supplementing provisions for the protection of the population, particularly by the standard procedure for radioecological impact assessment and determination of dose factors; (4) supplementing provisions on the use of radioactive substances in medicine and medical research; (5) supplementing provisions on health physics monitoring; (6) provisions for improving the supervision and controls in the transport of radioactive substances; (7) definition of activities and their assignment to the provisions of the Radiation Protection Ordinance; (8) revision of the waste management provisions of the Radiation Protection Ordinance. (HP) [de

  16. Albedo boundary conditions for global calculations of thermal nuclear reactors with the model of discrete ordinates to two energy groups

    International Nuclear Information System (INIS)

    Nunes, Carlos Eduardo de Araujo

    2011-01-01

    As neutron fission events do not take place in the non-multiplying regions of nuclear reactors, e.g., moderator, reflector, and structural core, these regions do not generate power and the computational efficiency of nuclear reactor global calculations can hence be improved by eliminating the explicit numerical calculations within the non-multiplying regions around the active domain. Discussed here is the computational efficiency of approximate discrete ordinates (SN) albedo boundary conditions for two-energy group eigenvalue problems in X, Y geometry. Albedo, the Latin word for w hiteness , was originally defined as the fraction of incident light reflected diffusely by a surface. This Latin word has remained the usual scientific term in astronomy and in this dissertation this concept is extended for the reflection of neutrons. The non-standard SN albedo substitutes approximately the reflector region around the active domain, as we neglect the transverse leakage terms within the non-multiplying reflector. Should the problem have no transverse leakage terms, i.e., one dimensional slab geometry, then the offered albedo boundary conditions are exact. By computational efficiency we mean analyzing the accuracy of the numerical results versus the CPU execution time of each run for a given model problem. Numerical results to two 1/4 symmetric test problems are shown to illustrate this efficiency analysis. (author)

  17. Optical ordinal optimization

    Science.gov (United States)

    Caulfield, H. John

    2000-07-01

    Ordinal optimization is a relatively new field of mathematics that seems never to have been applied to optics. Optics has made extensive use of traditional cardinal optimization. This paper explores the possibility that ordinal optimization might be useful in optics. The conclusion is: Not directly but indirectly.

  18. Simulating Ordinal Data

    Science.gov (United States)

    Ferrari, Pier Alda; Barbiero, Alessandro

    2012-01-01

    The increasing use of ordinal variables in different fields has led to the introduction of new statistical methods for their analysis. The performance of these methods needs to be investigated under a number of experimental conditions. Procedures to simulate from ordinal variables are then required. In this article, we deal with simulation from…

  19. Mathematical models and their applications to isotope studies in groundwater hydrology. Proceedings of a final research co-ordination meeting held in Vienna, 1-4 June 1993

    International Nuclear Information System (INIS)

    1994-12-01

    Tracer Techniques have proved to be useful tool for assessing, developing and water management of water resources. IAEA initiated a co-ordinated research programme (CRP) to improve quantitative evaluation of isotope data collected in groundwater hydrology. This publication compiles papers summarizing the results and findings of the work undertaken by participating institutes. Both mathematical modelling and their applications to isotope data on actual field results are covered. Refs, figs and tabs

  20. Finite Element Modelling of Infinite Euler Beams on Kelvin Foundations Exposed to Moving Loads in Convected Co-ordinates

    DEFF Research Database (Denmark)

    Andersen, Lars; Nielsen, Søren R.K.; Kirkegaard, Poul Henning

    2001-01-01

    The paper deals with the finite element method (FEM) solution of the problem with loads moving uniformly along an infinite Euler beam supported by a linear elastic Kelvin foundation with linear viscous damping. Initially, the problem is formulatedin a moving co-ordinate system following the load...

  1. Evaluation of a weighted test in the analysis of ordinal gait scores in an additivity model for five OP pesticides.

    Science.gov (United States)

    Appropriate statistical analyses are critical for evaluating interactions of mixtures with a common mode of action, as is often the case for cumulative risk assessments. Our objective is to develop analyses for use when a response variable is ordinal, and to test for interaction...

  2. Analytical reconstruction scheme for the coarse-mesh solution generated by the spectral nodal method for neutral particle discrete ordinates transport model in slab geometry

    International Nuclear Information System (INIS)

    Barros, Ricardo C.; Filho, Hermes Alves; Platt, Gustavo M.; Oliveira, Francisco Bruno S.; Militao, Damiano S.

    2010-01-01

    Coarse-mesh numerical methods are very efficient in the sense that they generate accurate results in short computational time, as the number of floating point operations generally decrease, as a result of the reduced number of mesh points. On the other hand, they generate numerical solutions that do not give detailed information on the problem solution profile, as the grid points can be located considerably away from each other. In this paper we describe two steps for the analytical reconstruction of the coarse-mesh solution generated by the spectral nodal method for neutral particle discrete ordinates (S N ) transport model in slab geometry. The first step of the algorithm is based on the analytical reconstruction of the coarse-mesh solution within each discretization cell of the grid set up on the spatial domain. The second step is based on the angular reconstruction of the discrete ordinates solution between two contiguous ordinates of the angular quadrature set used in the S N model. Numerical results are given so we can illustrate the accuracy of the two reconstruction techniques, as described in this paper.

  3. ON CHINESE ORDINAL CONSTRUCTIONS

    Directory of Open Access Journals (Sweden)

    Hui-Chin Tsai

    2011-06-01

    Full Text Available A Chinese ordinal construction in the form [di + Num + Cl + N] is ambiguous between a definite construal and an indefinite quantity construal. The morpheme di heads a DP, and the two readings of the ordinal expression can be attributed to the lexical ambiguity of the morpheme di. On the one hand, if the event is realized once, and there is an ordered set of objects in a single space within which the context of a sentence can verify a presupposed referential existence for the denotation of ordinal phrases, di is a [+strong] determiner giving rise to a definite reading. On the other hand, if the event is carried out more than once, no such an ordered set of objects is present in a single space, and the context of a sentence cannot verify a presupposed referential existence for the denotation of ordinal phrases, di is a [-strong] determiner with an additive function and results in an indefinite quantity reading.

  4. Radiation protection Ordinance

    International Nuclear Information System (INIS)

    1976-06-01

    This Ordinance lays down the licensing system for activities in Switzerland involving possible exposure to radiation, with the exception of nuclear installations, fuels and radioactive waste which, under the 1959 Atomic Energy Act, are subject to licensing. The Ordinance applies to the production, handling, use, storage, transport, disposal, import and export of radioactive substances and devices and articles containing them; and generally to any activity involving hazards caused by ionizing radiation. The Federal Public Health Office is the competent authority for granting licences. Provision is also made for the administrative conditions to be complied with for obtaining such licences as well as for technical measures required when engaged in work covered by the Ordinance. This consolidated version of the Ordinance contains all the successive amendments up to 26 September 1988. (NEA) [fr

  5. Evaluation of high-level waste pretreatment processes with an approximate reasoning model

    International Nuclear Information System (INIS)

    Bott, T.F.; Eisenhawer, S.W.; Agnew, S.F.

    1999-01-01

    The development of an approximate-reasoning (AR)-based model to analyze pretreatment options for high-level waste is presented. AR methods are used to emulate the processes used by experts in arriving at a judgment. In this paper, the authors first consider two specific issues in applying AR to the analysis of pretreatment options. They examine how to combine quantitative and qualitative evidence to infer the acceptability of a process result using the example of cesium content in low-level waste. They then demonstrate the use of simple physical models to structure expert elicitation and to produce inferences consistent with a problem involving waste particle size effects

  6. Evaluation of high-level waste pretreatment processes with an approximate reasoning model

    Energy Technology Data Exchange (ETDEWEB)

    Bott, T.F.; Eisenhawer, S.W.; Agnew, S.F.

    1999-04-01

    The development of an approximate-reasoning (AR)-based model to analyze pretreatment options for high-level waste is presented. AR methods are used to emulate the processes used by experts in arriving at a judgment. In this paper, the authors first consider two specific issues in applying AR to the analysis of pretreatment options. They examine how to combine quantitative and qualitative evidence to infer the acceptability of a process result using the example of cesium content in low-level waste. They then demonstrate the use of simple physical models to structure expert elicitation and to produce inferences consistent with a problem involving waste particle size effects.

  7. X-ray Ordinance

    International Nuclear Information System (INIS)

    Kramer, R.; Zerlett, G.

    1983-01-01

    This commentary, presented as volume 2 of the Deutsches Strahlenschutzrecht (German legislation on radiation protection) deals with the legal provisions of the ordinance on the protection against harmful effects of X-radiation (X-ray Ordinance - RoeV), of March 1, 1973 (announced in BGBl.I, page 173), as amended by the ordinance on the protection against harmful effects of ionizing radiation, of October 13, 1976 (announced in BGBl. I, page 2905). Thus volume 2 completes the task started with volume 1, namely to present a comprehensive view and account of the body of laws governing radiation protection, a task which was thought useful as developments in the FRG led to regulations being split up into the X-ray Ordinance, and the Radiation Protection Ordinance. In order to present a well-balanced commentary on the X-ray Ordinance, it was necessary to discuss the provisions both from the legal and the medical point of view. This edition takes into account the Fourth Public Notice of the BMA (Fed. Min. of Labour and Social Affairs) concerning the implementation of the X-ray Ordinance of January 4, 1982, as well as court decisions and literature published in this field, until September 1982. In addition, the judgment of the Federal Constitutional Court, dated October 19, 1982, concerning the voidness of the law on government liability, and two decisions by the Federal High Court, dated November 23, 1982, concerning the right to have insight into medical reports - of great significance in practice - have been considered. This commentary therefore is up to date with current developments. (orig.) [de

  8. Dynamic Modeling and Validation of a Biomass Hydrothermal Pretreatment Process - A Demonstration Scale Study

    DEFF Research Database (Denmark)

    Prunescu, Remus Mihail; Blanke, Mogens; Jakobsen, Jon Geest

    2015-01-01

    for the enzymatic hydrolysis process. Several by-products are also formed, which disturb and act as inhibitors downstream. The objective of this study is to formulate and validate a large scale hydrothermal pretreatment dynamic model based on mass and energy balances, together with a complex conversion mechanism......Hydrothermal pretreatment of lignocellulosic biomass is a cost effective technology for second generation biorefineries. The process occurs in large horizontal and pressurized thermal reactors where the biomatrix is opened under the action of steam pressure and temperature to expose cellulose...

  9. Modelling and L1 Adaptive Control of Temperature in Biomass Pretreatment

    DEFF Research Database (Denmark)

    Prunescu, Remus Mihail; Blanke, Mogens; Sin, Gürkan

    2013-01-01

    Biomass steam pretreatment is a key process in converting agricultural wastes to bioethanol. The pretreatment occurs in a large pressurized tank called a thermal reactor. Two key parameters influence the successfulness of the process: the reactor temperature, and the retention time. A particle pump......, and enthalpy-pressure and pressure-temperature dependencies. Nonlinear feed-forward terms are added in the control strategy. The process model, the control strategy, the application of the L1 adaptive controller and its tuning method based on minimizing a cost function represent novelties of this paper....

  10. Second research co-ordination meeting on development of reference input parameter library for nuclear model calculations of nuclear data. Summary report

    International Nuclear Information System (INIS)

    Oblozinsky, P.

    1996-03-01

    The present report contains the summary of the Second Research Co-ordination Meeting on ''Development of Reference Input Parameter Library for Nuclear Model Calculations of Nuclear Data'', held in Vienna, Austria, from 30 October to 3 November 1995. The library should serve the input for theoretical calculations of nuclear reaction data induced primarily with neutrons in the incident energy range below 30 MeV. Summarized are conclusions and recommendations of the meeting together with a detailed list of actions and deadlines. Attached is the agenda of the meeting, list of participants, and titles and abstracts of their presentations. (author)

  11. An analytical discrete ordinates solution for a nodal model of a two-dimensional neutron transport problem

    Energy Technology Data Exchange (ETDEWEB)

    Filho, J. F. P. [Institute de Matematica, Estatistica e Fisica, Universidade Federal do Rio Grande, Av. Italia, s/n, 96203-900 Rio Grande, RS (Brazil); Barichello, L. B. [Institute de Matematica, Universidade Federal do Rio Grande do Sul, Av. Bento Goncalves, 9500, 91509-900 Porto Alegre, RS (Brazil)

    2013-07-01

    In this work, an analytical discrete ordinates method is used to solve a nodal formulation of a neutron transport problem in x, y-geometry. The proposed approach leads to an important reduction in the order of the associated eigenvalue systems, when combined with the classical level symmetric quadrature scheme. Auxiliary equations are proposed, as usually required for nodal methods, to express the unknown fluxes at the boundary introduced as additional unknowns in the integrated equations. Numerical results, for the problem defined by a two-dimensional region with a spatially constant and isotropically emitting source, are presented and compared with those available in the literature. (authors)

  12. A single cell model for pretreatment of wood by microwave explosion

    Science.gov (United States)

    Xianjun Li; Yongdong Zhou; Yonglin Yan; Zhiyong Cai; Fu Feng

    2010-01-01

    A theoretical model was developed to better understand the process of microwave explosion treatment of wood cells. The cell expansion and critical conditions concerning pressure and temperature of ray parenchyma cells in Eucalyptus urophylla were simulated during microwave pretreatment. The results indicate that longitudinal and circumferential stresses were generated...

  13. Revision without ordinals

    NARCIS (Netherlands)

    Rivello, Edoardo

    2013-01-01

    We show that Herzberger’s and Gupta’s revision theories of truth can be recast in purely inductive terms, without any appeal neither to the transfinite ordinal numbers nor to the axiom of Choice. The result is presented in an abstract and general setting, emphasising both its validity for a wide

  14. A Deep Penetration Problem Calculation Using AETIUS:An Easy Modeling Discrete Ordinates Transport Code UsIng Unstructured Tetrahedral Mesh, Shared Memory Parallel

    Science.gov (United States)

    KIM, Jong Woon; LEE, Young-Ouk

    2017-09-01

    As computing power gets better and better, computer codes that use a deterministic method seem to be less useful than those using the Monte Carlo method. In addition, users do not like to think about space, angles, and energy discretization for deterministic codes. However, a deterministic method is still powerful in that we can obtain a solution of the flux throughout the problem, particularly as when particles can barely penetrate, such as in a deep penetration problem with small detection volumes. Recently, a new state-of-the-art discrete-ordinates code, ATTILA, was developed and has been widely used in several applications. ATTILA provides the capabilities to solve geometrically complex 3-D transport problems by using an unstructured tetrahedral mesh. Since 2009, we have been developing our own code by benchmarking ATTILA. AETIUS is a discrete ordinates code that uses an unstructured tetrahedral mesh such as ATTILA. For pre- and post- processing, Gmsh is used to generate an unstructured tetrahedral mesh by importing a CAD file (*.step) and visualizing the calculation results of AETIUS. Using a CAD tool, the geometry can be modeled very easily. In this paper, we describe a brief overview of AETIUS and provide numerical results from both AETIUS and a Monte Carlo code, MCNP5, in a deep penetration problem with small detection volumes. The results demonstrate the effectiveness and efficiency of AETIUS for such calculations.

  15. Enhanced methane production and its kinetics model of thermally pretreated lignocellulose waste material.

    Science.gov (United States)

    Veluchamy, C; Kalamdhad, Ajay S

    2017-10-01

    The objective of the study was to assess the effect of substrate concentration by specific methanogenic activity (SMA) of thermally pretreated pulp and paper mill sludge. Different substrate concentration through food to microorganism ratio varied from 1.0 to 3.0 was carried out in a mesophilic condition as biochemical methane potential assay. Experimental results offered that cellulose removal rate spikes up to 60.2%. The specific methane gas production and biodegradability were increased up to 303mL of CH 4 /g VS and 73% respectively. By increasing the substrate concentration, SMA was significantly improved in a linear manner. The net energy of 8735kJ was gained after thermal pretreatment. In addition to that three kinetics model were used, among that the modified Gompertz and logistic function models represent and reproduce the experimental data, while the earlier has the better fit. Copyright © 2017 Elsevier Ltd. All rights reserved.

  16. Understanding mild acid pretreatment of sugarcane bagasse through particle scale modeling.

    Science.gov (United States)

    Greenwood, Ava A; Farrell, Troy W; O'Hara, Ian M

    2013-12-01

    Sugarcane bagasse is an abundant and sustainable resource, generated as a by-product of sugarcane milling. The cellulosic material within bagasse can be broken down into glucose molecules and fermented to produce ethanol, making it a promising feedstock for biofuel production. Mild acid pretreatment hydrolyses the hemicellulosic component of biomass, thus allowing enzymes greater access to the cellulosic substrate during saccharification. A particle-scale mathematical model describing the mild acid pretreatment of sugarcane bagasse has been developed, using a volume averaged framework. Discrete population-balance equations are used to characterise the polymer degradation kinetics, and diffusive effects account for mass transport within the cell wall of the bagasse. As the fibrous material hydrolyses over time, variations in the porosity of the cell wall and the downstream effects on the reaction kinetics are accounted for using conservation of volume arguments. Non-dimensionalization of the model equations reduces the number of parameters in the system to a set of four dimensionless ratios that compare the timescales of different reaction and diffusion events. Theoretical yield curves are compared to macroscopic experimental observations from the literature and inferences are made as to constraints on these "unknown" parameters. These results enable connections to be made between experimental data and the underlying thermodynamics of acid pretreatment. Consequently, the results suggest that data-fitting techniques used to obtain kinetic parameters should be carefully applied, with prudent consideration given to the chemical and physiological processes being modeled. © 2013 Wiley Periodicals, Inc.

  17. Radiation (Safety Control) Ordinance 1978

    International Nuclear Information System (INIS)

    1978-01-01

    This Ordinance provides for the control, regulation, possession, use and transport of radioactive substance and irradiating apparatus. The Director of Health is responsible for administration of the Ordinance, which contains detailed provisions concerning the terms and conditions of licences, duties of licensees, medical examinations, maximum radiation doses, precautions to be taken to avoid exceeding such doses. The Ordinance also lays down a system of record-keeping and registration as well as packaging specifications for the transport of radioactive substances. (NEA) [fr

  18. Proposed Ordinance for the Regulation of Cable Television. Working Draft.

    Science.gov (United States)

    Chicago City Council, IL.

    A model ordinance is proposed for the regulation of cable television in the city of Chicago. It defines the language of the ordinance, sets forth the method of granting franchises, and describes the terms of the franchises. The duties of a commission to regulate cable television are listed and the method of selecting commission members is…

  19. A test for ordinal measurement invariance

    NARCIS (Netherlands)

    Ligtvoet, R.; Millsap, R.E.; Bolt, D.M.; van der Ark, L.A.; Wang, W.-C.

    2015-01-01

    One problem with the analysis of measurement invariance is the reliance of the analysis on having a parametric model that accurately describes the data. In this paper an ordinal version of the property of measurement invariance is proposed, which relies only on nonparametric restrictions. This

  20. The Second Ordinance for Amendment of the Radiation Protection Ordinance

    International Nuclear Information System (INIS)

    Czajka, D.

    1989-01-01

    This Second Ordinance for Amendment of the Radiation Protection Ordinance has modified the most important legal provisions supplementing the Atomic Energy Act. But looking closer at the revised version of the Ordinance, many an amendment turns out to be just a new facade on the old brickwork. The article critically reviews the most important amendments, stating that the main principles have remained untouched, and discussing the modification of limiting values, the definition of regulatory scopes, the new meaning of the term 'wastes containing nuclear fuel', and the regulatory scope of provisions governing radioactive substances and their medical applications. (orig./RST) [de

  1. L-carnitine pretreatment protects slow-twitch skeletal muscles in a rat model of ischemia-reperfusion injury.

    Science.gov (United States)

    Demirel, Mert; Kaya, Burak; Cerkez, Cem; Ertunc, Mert; Sara, Yildirim

    2013-10-01

    Ischemia-reperfusion (I/R) injury negatively affects the outcome of surgical interventions for amputated or severely traumatized extremities. This study aimed to evaluate the protective role of l-carnitine on the contractile properties of fast-twitch (extensor digitorum longus [EDL]) and slow-twitch (soleus [SOL]) skeletal muscles following I/R-induced injury in a rat model. Rats were divided into 4 groups (1) saline pretreatment, (2) l-carnitine pretreatment, (3) saline pretreatment and I/R, and (4) l-carnitine pretreatment and I/R. Twitch and tetanic contractions in the EDL and SOL muscles in each group were recorded. Additionally, a fatigue protocol was performed in these muscles. Twitch and tetanic contraction amplitudes were lower in the EDL and SOL muscles in which I/R was induced (P < .01). l-Carnitine pretreatment significantly increased tetanic contraction amplitude in the SOL muscles following I/R (P < .01) but not in the EDL muscles. l-Carnitine pretreatment did not alter the fatigue response in any of the muscles.

  2. Development of an estimation model for the evaluation of the energy requirement of dilute acid pretreatments of biomass☆

    Science.gov (United States)

    Mafe, Oluwakemi A.T.; Davies, Scott M.; Hancock, John; Du, Chenyu

    2015-01-01

    This study aims to develop a mathematical model to evaluate the energy required by pretreatment processes used in the production of second generation ethanol. A dilute acid pretreatment process reported by National Renewable Energy Laboratory (NREL) was selected as an example for the model's development. The energy demand of the pretreatment process was evaluated by considering the change of internal energy of the substances, the reaction energy, the heat lost and the work done to/by the system based on a number of simplifying assumptions. Sensitivity analyses were performed on the solid loading rate, temperature, acid concentration and water evaporation rate. The results from the sensitivity analyses established that the solids loading rate had the most significant impact on the energy demand. The model was then verified with data from the NREL benchmark process. Application of this model on other dilute acid pretreatment processes reported in the literature illustrated that although similar sugar yields were reported by several studies, the energy required by the different pretreatments varied significantly. PMID:26109752

  3. Development of an estimation model for the evaluation of the energy requirement of dilute acid pretreatments of biomass.

    Science.gov (United States)

    Mafe, Oluwakemi A T; Davies, Scott M; Hancock, John; Du, Chenyu

    2015-01-01

    This study aims to develop a mathematical model to evaluate the energy required by pretreatment processes used in the production of second generation ethanol. A dilute acid pretreatment process reported by National Renewable Energy Laboratory (NREL) was selected as an example for the model's development. The energy demand of the pretreatment process was evaluated by considering the change of internal energy of the substances, the reaction energy, the heat lost and the work done to/by the system based on a number of simplifying assumptions. Sensitivity analyses were performed on the solid loading rate, temperature, acid concentration and water evaporation rate. The results from the sensitivity analyses established that the solids loading rate had the most significant impact on the energy demand. The model was then verified with data from the NREL benchmark process. Application of this model on other dilute acid pretreatment processes reported in the literature illustrated that although similar sugar yields were reported by several studies, the energy required by the different pretreatments varied significantly.

  4. The determinants of the growth expectations of the early-stage entrepreneurs (TEA using the ordinal logistic model (OLM: the case of Turkey

    Directory of Open Access Journals (Sweden)

    Ahmet Özçam

    2010-01-01

    Full Text Available This study uses the Ordinal Logistic Model (OLM to analyze the determinants of the growth expectations of total early-stage entrepreneurship activity (TEA expressed in terms of new jobs to be created within their firms in four categories. Specifically, given the increasing importance of entrepreneurship in job creation, innovation and economic growth, we try to inquire into the question of why some of the new entrepreneurs and not the others expect a rapid development of their ventures. The data from the Global Entrepreneurship Monitor (GEM for the years 2006-2008 for Turkey were employed. Our findings indicate that the personal characteristics of the early-stage Turkish entrepreneurs such as gender, education and household income, in addition to their motivation and current size of their businesses are important factors in resolving the prevalence of high-expectation new firms. Moreover, some scenarios particular to some sub-groups or population cells of Turkish developing entrepreneurs which may create the bulk of high-expectation entrepreneurial pursuit were conducted using OLM. As far as the policy implications are concerned, the availability and access of capital funding to early-stage entrepreneurs and an education system more relevant to today’s competitive world might both contribute better to Turkish economy’s prosperity, and seems to be very important for policy considerations.

  5. Tree Ordination as Invented Tradition

    Directory of Open Access Journals (Sweden)

    Avery Morrow

    2012-01-01

    Full Text Available The symbolic ordination of trees as monks in Thailand is widely perceived in Western scholarship to be proof of the power of Buddhism to spur ecological thought. However, a closer analysis of tree ordination demonstrates that it is not primarily about Buddhist teaching, but rather is an invented tradition based on the sanctity of Thai Buddhist symbols as well as those of spirit worship and the monarchy. Tree ordinations performed by non-Buddhist minorities in Thailand do not demonstrate a religious commitment but rather a political one.

  6. Validation and uncertainty analysis of a pre-treatment 2D dose prediction model

    Science.gov (United States)

    Baeza, Jose A.; Wolfs, Cecile J. A.; Nijsten, Sebastiaan M. J. J. G.; Verhaegen, Frank

    2018-02-01

    Independent verification of complex treatment delivery with megavolt photon beam radiotherapy (RT) has been effectively used to detect and prevent errors. This work presents the validation and uncertainty analysis of a model that predicts 2D portal dose images (PDIs) without a patient or phantom in the beam. The prediction model is based on an exponential point dose model with separable primary and secondary photon fluence components. The model includes a scatter kernel, off-axis ratio map, transmission values and penumbra kernels for beam-delimiting components. These parameters were derived through a model fitting procedure supplied with point dose and dose profile measurements of radiation fields. The model was validated against a treatment planning system (TPS; Eclipse) and radiochromic film measurements for complex clinical scenarios, including volumetric modulated arc therapy (VMAT). Confidence limits on fitted model parameters were calculated based on simulated measurements. A sensitivity analysis was performed to evaluate the effect of the parameter uncertainties on the model output. For the maximum uncertainty, the maximum deviating measurement sets were propagated through the fitting procedure and the model. The overall uncertainty was assessed using all simulated measurements. The validation of the prediction model against the TPS and the film showed a good agreement, with on average 90.8% and 90.5% of pixels passing a (2%,2 mm) global gamma analysis respectively, with a low dose threshold of 10%. The maximum and overall uncertainty of the model is dependent on the type of clinical plan used as input. The results can be used to study the robustness of the model. A model for predicting accurate 2D pre-treatment PDIs in complex RT scenarios can be used clinically and its uncertainties can be taken into account.

  7. Biomass pretreatment

    Science.gov (United States)

    Hennessey, Susan Marie; Friend, Julie; Elander, Richard T; Tucker, III, Melvin P

    2013-05-21

    A method is provided for producing an improved pretreated biomass product for use in saccharification followed by fermentation to produce a target chemical that includes removal of saccharification and or fermentation inhibitors from the pretreated biomass product. Specifically, the pretreated biomass product derived from using the present method has fewer inhibitors of saccharification and/or fermentation without a loss in sugar content.

  8. Pretreatment with intravenous lipid emulsion reduces mortality from cocaine toxicity in a rat model.

    Science.gov (United States)

    Carreiro, Stephanie; Blum, Jared; Hack, Jason B

    2014-07-01

    We compare the effects of intravenous lipid emulsion and normal saline solution pretreatment on mortality and hemodynamic changes in a rat model of cocaine toxicity. We hypothesize that intravenous lipid emulsion will decrease mortality and hemodynamic changes caused by cocaine administration compared with saline solution. Twenty male Sprague-Dawley rats were sedated and randomized to receive intravenous lipid emulsion or normal saline solution, followed by a 10 mg/kg bolus of intravenous cocaine. Continuous monitoring included intra-arterial blood pressure, pulse rate and ECG tracing. Endpoints included a sustained undetectable mean arterial pressure (MAP) or return to baseline MAP for 5 minutes. The log-rank test was used to compare mortality. A mixed-effect repeated-measures ANOVA was used to estimate the effects of group (intravenous lipid emulsion versus saline solution), time, and survival on change in MAP, pulse rate, or pulse pressure. In the normal saline solution group, 7 of 10 animals died compared with 2 of 10 in the intravenous lipid emulsion group. The survival rate of 80% (95% confidence interval 55% to 100%) for the intravenous lipid emulsion rats and 30% (95% confidence interval 0.2% to 58%) for the normal saline solution group was statistically significant (P=.045). Intravenous lipid emulsion pretreatment decreased cocaine-induced cardiovascular collapse and blunted hypotensive effects compared with normal saline solution in this rat model of acute lethal cocaine intoxication. Intravenous lipid emulsion should be investigated further as a potential adjunct in the treatment of severe cocaine toxicity. Copyright © 2013 American College of Emergency Physicians. Published by Mosby, Inc. All rights reserved.

  9. Effect of root-extracts of Ficus benghalensis (Banyan) in memory, anxiety, muscle co-ordination and seizure in animal models.

    Science.gov (United States)

    Panday, Dipesh Raj; Rauniar, G P

    2016-11-03

    Ficus benghalensis L. (Banyan) is a commonly found tree in Eastern Nepal. Its different plant parts are used for various neurological ailments. This study was performed in mice to see its effects in various neuropharmacological parameters. Passive-avoidance (memory), Open-field (anxiety), Pentobarbital-induced Sleep potentiation (sleep), Rota-rod (muscle-co-ordination), Pentylenetetrazol-Induced and Maximal Electroshock Seizure Tests were performed. Sample size was calculated using G*Power 3.1.9.2. Aqueous root extracts (Soxhlet method) of Ficus benghalensis 100 mg/kg and 200 mg/kg with negative and positive controls were used. The experimental results were represented as Mean ± SD. P-value was set at 120 s) and Diazepam (62.07 s + 43.83 s) PTZ model showed that 100 mg/kg significantly (P = 0.004) delayed seizure-onset (184.40s + 36.36 s) compared to Normal Saline (101.79 s + 22.81 s), however, in MES model 200 mg/kg significantly (P = 0.000) prolonged tonic hind-limb extension (17.57 s + 2.15 s) compared to Normal Saline (13.55 s + 2.75 s) or Phenytoin (00.00s + 00.00s). Aerial roots of Ficus benghalensis have memory-enhancing, anxiolytic, musclerelaxant, and seizure-modifying effect.

  10. Modelling of the transfer of radiocaesium from deposition to lake ecosystems. Report of the VAMP aquatic working group. Part of the IAEA/CEC co-ordinated research programme on the validation of environmental model predictions (VAMP)

    International Nuclear Information System (INIS)

    2000-03-01

    The environmental impact of releases of radionuclides from nuclear installations can be predicted using assessment models. For such assessments information on their reliability must be provided. Ideally models should be developed and tested using actual data on the transfer of the nuclides which are site specific for the environment being modelled. In the past, generic data have often been taken from environmental contamination that resulted from the fallout from the nuclear weapons testing in the 1950s and 1960s or from laboratory experiments. However, it has always been recognized that there may be differences in the physico-chemical form of the radionuclides from these sources as compared to those that could be released from nuclear installations. Furthermore, weapons fallout was spread over time; it did not provide a single pulse which is generally used in testing models that predict time dependence. On the other hand, the Chernobyl accident resulted in a single pulse, which was detected and measured in a variety of environments throughout Europe. The acquisition of these new data sets justified the establishment of an international programme aimed at collating data from different IAEA Member States and at co-ordinating work on new model testing studies. The IAEA established a Co-ordinated Research Programme (CRP) on 'Validation of Environmental Model Predictions' (VAMP). The principal objectives of the VAMP Co-ordinated Research Programme were: (a) To facilitate the validation of assessment models for radionuclide transfer in the terrestrial, aquatic and urban environments. It is envisaged that this will be achieved by acquiring suitable sets of environmental data from the results of the national research and monitoring programmes established following the Chernobyl release. (b) To guide, if necessary, environmental research and monitoring efforts to acquire data for the validation of models used to assess the most significant radiological exposure pathways

  11. Multidimensional electron-photon transport with standard discrete ordinates codes

    International Nuclear Information System (INIS)

    Drumm, C.R.

    1995-01-01

    A method is described for generating electron cross sections that are compatible with standard discrete ordinates codes without modification. There are many advantages of using an established discrete ordinates solver, e.g. immediately available adjoint capability. Coupled electron-photon transport capability is needed for many applications, including the modeling of the response of electronics components to space and man-made radiation environments. The cross sections have been successfully used in the DORT, TWODANT and TORT discrete ordinates codes. The cross sections are shown to provide accurate and efficient solutions to certain multidimensional electronphoton transport problems

  12. Quality assessment and shelf life modeling of pulsed electric field pretreated osmodehydrofrozen kiwifruit slices

    Directory of Open Access Journals (Sweden)

    Efimia Dermesonlouoglou

    2018-04-01

    Full Text Available The objective of this workwas to investigate the potential use of pulsed electric field (PEF in combination with osmotic dehydration (OD as a pre-freezing step and to evaluate the effect on quality characteristics and shelf life of frozen kiwifruit. Peeled kiwifruit was subjected to PEF (1.8 kV/cm, sliced and treated in OD-solution [containing glycerol, maltodextrin, trehalose, ascorbic acid, calcium chloride, citric acid, sodium chloride; 1/5 (wfruit/wsolution] for 30 and 60 min at 35 °C. Combined, PEF only and OD only treated samples as well as nontreated and blanched (80 °C, 60 s samples were frozen and stored at constant (-5, -10, -15, -25 °C and dynamic temperature conditions (-18 °C-3 d, -8 °C-2.5 d, -15 °C-3 d. Quality of frozen samples was evaluated by means of drip loss, colour, texture, vitamin C and sensory evaluation (1-9 scale; and shelf life (SL was calculated. Nontreated and blanched samples presented high drip loss and tissue softening (instrumentally measured as Fmax decrease. The tissue integrity was well retained in all osmotically pretreated samples. PEF pretreatment caused increase of fruit whiteness (increase of L value and yellowness (a and/or b value increase; SL calculation was based on colour change. All OD samples had high vitamin content (24.6 mg/100 g fresh material compared to 138-154 mg/100 g osmodehydrated material; PEF led to 93% (of the initial vitamin retention; blanched samples showed the lowest retention (86.9% of the initial (criteria for SL calculation. OD and combined PEF-OD treatment increased the shelf life of frozen kiwifruit (up to 3 times; based on sensorial criteria. The developed kinetic models for colour change, vitamin loss, and sensory quality deterioration were validated at dynamic temperature conditions. PEF pretreated OD (at significantly shorter time, 30 min compared to 60 min kiwifruits retained optimum quality and sensory characteristics. PEF and OD could be used as a preprocessing

  13. Semi-supervised learning for ordinal Kernel Discriminant Analysis.

    Science.gov (United States)

    Pérez-Ortiz, M; Gutiérrez, P A; Carbonero-Ruz, M; Hervás-Martínez, C

    2016-12-01

    Ordinal classification considers those classification problems where the labels of the variable to predict follow a given order. Naturally, labelled data is scarce or difficult to obtain in this type of problems because, in many cases, ordinal labels are given by a user or expert (e.g. in recommendation systems). Firstly, this paper develops a new strategy for ordinal classification where both labelled and unlabelled data are used in the model construction step (a scheme which is referred to as semi-supervised learning). More specifically, the ordinal version of kernel discriminant learning is extended for this setting considering the neighbourhood information of unlabelled data, which is proposed to be computed in the feature space induced by the kernel function. Secondly, a new method for semi-supervised kernel learning is devised in the context of ordinal classification, which is combined with our developed classification strategy to optimise the kernel parameters. The experiments conducted compare 6 different approaches for semi-supervised learning in the context of ordinal classification in a battery of 30 datasets, showing (1) the good synergy of the ordinal version of discriminant analysis and the use of unlabelled data and (2) the advantage of computing distances in the feature space induced by the kernel function. Copyright © 2016 Elsevier Ltd. All rights reserved.

  14. Coupling of a discrete ordinate 3-D radiant heat transfer model with the PHOENICS fluid mechanics software; Couplage d`un modele radiatif tridimensionnel aux ordonnees discretes au logiciel de mecanique des fluides phoenics

    Energy Technology Data Exchange (ETDEWEB)

    Muller, J. [IRSID, Institut de Recherches Siderurgie, 57 - Maizieres-les-Metz (France)

    1996-12-31

    Radiant heat transfer is the main solution retained in many iron and steel metallurgy installations (re-heating and annealing furnaces etc..). Today, it has become important to dispose of performing radiant heat transfer models in heat transfer and fluid mechanics simulation softwares, and well adapted to multidimensional industrial problems. This work presents the discrete ordinate radiant heat transfer model developed at the IRSID (the French institute of research in iron and steel metallurgy) and coupled with the PHOENICS heat transfer-fluid mechanics software. Three modeling approaches are presented concerning the radiative properties of gases (H{sub 2}O-CO{sub 2}). A ``weighted grey gases sum`` model gives satisfactory results for several 1-D validation cases. (J.S.) 20 refs.

  15. Fuzzy-logic modeling of Fenton's oxidation of anaerobically pretreated poultry manure wastewater.

    Science.gov (United States)

    Yetilmezsoy, Kaan

    2012-07-01

    A multiple inputs and multiple outputs (MIMO) fuzzy-logic-based model was proposed to estimate color and chemical oxygen demand (COD) removal efficiencies in the post-treatment of anaerobically pretreated poultry manure wastewater effluent using Fenton's oxidation process. Three main input variables including initial pH, Fe+2, and H2O2 dosages were fuzzified in a new numerical modeling scheme by the use of an artificial intelligence-based approach. Trapezoidal membership functions with eight levels were conducted for the fuzzy subsets, and a Mamdani-type fuzzy inference system was used to implement a total of 70 rules in the IF-THEN format. The product (prod) and the center of gravity (centroid) methods were applied as the inference operator and defuzzification methods, respectively. Fuzzy-logic predicted results were compared with the outputs of two first-order polynomial regression models derived in the scope of this study. Estimated results were also compared to the multiple regression approach by means of various descriptive statistical indicators, such as root mean-squared error, index of agreement, fractional variance, proportion of systematic error, etc. Results of the statistical analysis clearly revealed that, compared to conventional regression models, the proposed MIMO fuzzy-logic model produced very smaller deviations and demonstrated a superior predictive performance on forecasting of color and COD removal efficiencies with satisfactory determination coefficients over 0.98. Due to high capability of the fuzzy-logic methodology in capturing the non-linear interactions, it was demonstrated that a complex dynamic system, such as Fenton's oxidation, could be easily modeled.

  16. Ultrasound Pretreatment as an Useful Tool to Enhance Egg White Protein Hydrolysis: Kinetics, Reaction Model, and Thermodinamics.

    Science.gov (United States)

    Jovanović, Jelena R; Stefanović, Andrea B; Šekuljica, Nataša Ž; Tanasković, Sonja M Jakovetić; Dojčinović, Marina B; Bugarski, Branko M; Knežević-Jugović, Zorica D

    2016-09-28

    The impact of ultrasound waves generated by probe-type sonicator and ultrasound cleaning bath on egg white protein susceptibility to hydrolysis by alcalase compared to both thermal pretreatment and conventional enzymatic hydrolysis was quantitatively investigated. A series of hydrolytic reactions was carried out in a stirred tank reactor at different substrate concentrations, enzyme concentrations, and temperatures using untreated, and pretreated egg white proteins (EWPs). The kinetic model based on substrate inhibition and second-order enzyme deactivation successfully predicts the experimental behavior providing an effective tool for comparison and optimization. The ultrasound pretreatments appear to greatly improve the enzymatic hydrolysis of EWPs under different conditions when compare to other methods. The apparent reaction rate constants for proteolysis (k 2 ) are 0.009, 0.011, 0.053, and 0.045 min -1 for untreated EWPs, and those pretreated with heat, probe-type sonicator, and ultrasound cleaning bath technologies, respectively. The ultrasound pretreatment also decreases hydrolysis activation (E a ) and enzyme deactivation (E d ) energy, enthalpy (ΔH), and entropy (ΔS) of activation and for the probe-type sonication this decrease is 61.7%, 61.6%, 63.6%, and 32.2%, respectively, but ultrasound has little change in Gibbs free energy value in the temperature range of 318 to 338 K. The content of sulfhydryl groups and ζ potential show a significant increase (P < 0.05) for both applied ultrasound pretreatments and the reduction of particle size distribution are achieved, providing some evidence that the ultrasound causes EWP structural changes affecting the proteolysis rate. © 2016 Institute of Food Technologists®

  17. Scoring ordinal variables for constructing composite indicators

    Directory of Open Access Journals (Sweden)

    Marica Manisera

    2013-05-01

    Full Text Available In order to provide composite indicators of latent variables, for example of customer satisfaction, it is opportune to identify the structure of the latent variable, in terms of the assignment of items to the subscales defining the latent variable. Adopting the reflective model, the impact of four different methods of scoring ordinal variables on the identification of the true structure of latent variables is investigated. A simulation study composed of 5 steps is conducted: (1 simulation of population data with continuous variables measuring a two-dimensional latent variable with known structure; (2 draw of a number of random samples; (3 discretization of the continuous variables according to different distributional forms; (4 quantification of the ordinal variables obtained in step (3 according to different methods; (5 construction of composite indicators and verification of the correct assignment of variables to subscales by the multiple group method and the factor analysis. Results show that the considered scoring methods have similar performances in assigning items to subscales, and that, when the latent variable is multinormal, the distributional form of the observed ordinal variables is not determinant in suggesting the best scoring method to use.

  18. Biosorption of diazinon by a pre-treated alimentary industrial waste: equilibrium and kinetic modeling

    Science.gov (United States)

    Yeddou Mezenner, N.; Lagha, H.; Kais, H.; Trari, M.

    2017-11-01

    This study explores the feasibility of pre-treated coffee waste (PCW) as biosorbent for the removal of diazinon. The effect of the pesticide concentration (6-20 mg L-1), contact time, adsorbent dose (0.2-1.2 g L-1), solution pH (3-11.5), temperature (15-40 °C) and co-existing inorganic ions (H2PO4 -, NO3 -) on the diazinon biosorption over PCW is investigated. The experimental results indicate an optimal pH of 7.3 for the diazinon elimination on PCW (1 g L-1). The Langmuir model describes well the isotherm data with a high regression coefficient ( R 2 > 0.990) and a maximum monolayer biosorption capacity of 18.52 mg g-1 at 15 °C. It is also observed that the intra-particle diffusion is not the rate-controlling step. A comparison is evaluated between the pseudo-second-order and intra-particle diffusion kinetic models; the experimental data are well fitted by the pseudo-second-order kinetic model. The biosorption capacity decreases with increasing temperature for a diazinon concentration of 10 mg L-1. The negative enthalpy Δ H° (-63.57 kJ/mol) indicates that the diazinon biosorption onto PCW is exothermic. Under optimal conditions, the biosorption reaches 95% after 90 min. The removal efficiency decreases from 95 to 65.67 and 48.9% for the diazinon alone and in the presence of NO3 - and H2PO4 - (100 mg L-1), respectively.

  19. Pretreatment with Fish Oil-Based Lipid Emulsion Modulates Muscle Leukocyte Chemotaxis in Murine Model of Sublethal Lower Limb Ischemia

    Directory of Open Access Journals (Sweden)

    Yao-Ming Shih

    2017-01-01

    Full Text Available This study investigated the effects of a fish oil- (FO- based lipid emulsion on muscle leukocyte chemotaxis and inflammatory responses in a murine model of limb ischemia-reperfusion (IR injury. Mice were assigned randomly to 1 sham (sham group, 2 ischemic groups, and 2 IR groups. The sham group did not undergo the ischemic procedure. The mice assigned to the ischemic or IR groups were pretreated intraperitoneally with either saline or FO-based lipid emulsion for 3 consecutive days. The IR procedure was induced by applying a 4.5 oz orthodontic rubber band to the left thigh above the greater trochanter for 120 min and then cutting the band to allow reperfusion. The ischemic groups were sacrificed immediately while the IR groups were sacrificed 24 h after reperfusion. Blood, IR-injured gastrocnemius, and lung tissues were collected for analysis. The results showed that FO pretreatment suppressed the local and systemic expression of several IR-induced proinflammatory mediators. Also, the FO-pretreated group had lower blood Ly6ChiCCR2hi monocyte percentage and muscle M1/M2 ratio than the saline group at 24 h after reperfusion. These findings suggest that FO pretreatment may have a protective role in limb IR injury by modulating the expression of proinflammatory mediators and regulating the polarization of macrophage.

  20. Spatial Representation of Ordinal Information

    Directory of Open Access Journals (Sweden)

    Meng eZhang

    2016-04-01

    Full Text Available Right hand responds faster than left hand when shown larger numbers and vice-versa when shown smaller numbers (the SNARC effect. Accumulating evidence suggests that the SNARC effect may not be exclusive for numbers and can be extended to other ordinal sequences (e.g., months or letters in the alphabet as well. In this study, we tested the SNARC effect with a non-numerically ordered sequence: The Chinese notations for the color spectrum (Red, Orange, Yellow, Green, Blue, Indigo, and Violet. Chinese color word sequence reserves relatively weak ordinal information, because each element color in the sequence normally appears in non-sequential contexts, making it ideal to test the spatial organization of sequential information that was stored in the long-term memory. This study found a reliable SNARC-like effect for Chinese color words (deciding whether the presented color word was before or after the reference color word green, suggesting that, without access to any quantitative information or exposure to any previous training, ordinal representation can still activate a sense of space. The results support that weak ordinal information without quantitative magnitude encoded in the long-term memory can activate spatial representation in a comparison task.

  1. Spatial Representation of Ordinal Information.

    Science.gov (United States)

    Zhang, Meng; Gao, Xuefei; Li, Baichen; Yu, Shuyuan; Gong, Tianwei; Jiang, Ting; Hu, Qingfen; Chen, Yinghe

    2016-01-01

    Right hand responds faster than left hand when shown larger numbers and vice-versa when shown smaller numbers (the SNARC effect). Accumulating evidence suggests that the SNARC effect may not be exclusive for numbers and can be extended to other ordinal sequences (e.g., months or letters in the alphabet) as well. In this study, we tested the SNARC effect with a non-numerically ordered sequence: the Chinese notations for the color spectrum (Red, Orange, Yellow, Green, Blue, Indigo, and Violet). Chinese color word sequence reserves relatively weak ordinal information, because each element color in the sequence normally appears in non-sequential contexts, making it ideal to test the spatial organization of sequential information that was stored in the long-term memory. This study found a reliable SNARC-like effect for Chinese color words (deciding whether the presented color word was before or after the reference color word "green"), suggesting that, without access to any quantitative information or exposure to any previous training, ordinal representation can still activate a sense of space. The results support that weak ordinal information without quantitative magnitude encoded in the long-term memory can activate spatial representation in a comparison task.

  2. Detrimental effects of rat mesenchymal stromal cell pre-treatment in a model of acute kidney rejection

    Directory of Open Access Journals (Sweden)

    Martina eSeifert

    2012-07-01

    Full Text Available Mesenchymal stromal cells (MSC have shown immunomodulatory and tissue repair potential including partial tolerance induction by pre-treatment of donor-specific cells in a rat heart transplantation model. Very recently, we could show that autologous MSC attenuated ischemia reperfusion injury in a highly mismatched donor-recipient rat kidney transplant model. Therefore, we investigated donor-specific MSC pre-treatment in this rat kidney transplantation model to study whether graft function could be improved, or if tolerance could be induced.Donor- and recipient-type MSC or PBS as a control were injected i.v. four days before kidney transplantation. Mycophenolate mofetil (MMF immunosuppression (20 mg/kg body weight was applied for 7 days. Kidney grafts and spleens were harvested between days 8-10 and analyzed by quantitative RT-PCR and immunohistology. In addition, creatinine levels in the blood were measured and serum was screened for the presence of donor-specific antibodies.Surprisingly, application of both donor- and recipient-specific MSC resulted in enhanced humoral immune responses verified by intragraft B cell infiltration and complement factor C4d deposits. Moreover, signs of inflammation and rejection were generally enhanced in both MSC-treated groups relative to PBS control group. Additionally, pre-treatment with donor-specific MSC significantly enhanced the level of donor-specific antibody formation when compared with PBS- or recipient-MSC-treated groups. Pre-treatment with both MSC types resulted in a higher degree of kidney cortex tissue damage and elevated creatinine levels at the time point of rejection. Thus, MSC pre-sensitization in this model impairs the allograft outcome.Our data from this pre-clinical kidney transplantation model indicate that pre-operative MSC administration may not be optimal in kidney transplantation and caution must be exerted before moving forward with clinical studies in order to avoid adverse effects.

  3. 2D co-ordinate transformation based on a spike timing-dependent plasticity learning mechanism.

    Science.gov (United States)

    Wu, QingXiang; McGinnity, Thomas Martin; Maguire, Liam; Belatreche, Ammar; Glackin, Brendan

    2008-11-01

    In order to plan accurate motor actions, the brain needs to build an integrated spatial representation associated with visual stimuli and haptic stimuli. Since visual stimuli are represented in retina-centered co-ordinates and haptic stimuli are represented in body-centered co-ordinates, co-ordinate transformations must occur between the retina-centered co-ordinates and body-centered co-ordinates. A spiking neural network (SNN) model, which is trained with spike-timing-dependent-plasticity (STDP), is proposed to perform a 2D co-ordinate transformation of the polar representation of an arm position to a Cartesian representation, to create a virtual image map of a haptic input. Through the visual pathway, a position signal corresponding to the haptic input is used to train the SNN with STDP synapses such that after learning the SNN can perform the co-ordinate transformation to generate a representation of the haptic input with the same co-ordinates as a visual image. The model can be applied to explain co-ordinate transformation in spiking neuron based systems. The principle can be used in artificial intelligent systems to process complex co-ordinate transformations represented by biological stimuli.

  4. Caustic-Side Solvent-Extraction Modeling for Hanford Interim Pretreatment System

    Energy Technology Data Exchange (ETDEWEB)

    Moyer, B.A.; Birdwell, J.F.; Delmau, L. H.; McFarlane, J.

    2008-06-01

    The purpose of this work is to examine the applicability of the Caustic-Side Solvent Extraction (CSSX) process for the removal of cesium from Hanford tank-waste supernatant solutions in support of the Hanford Interim Pretreatment System (IPS). The Hanford waste types are more challenging than those at the Savannah River Site (SRS) in that they contain significantly higher levels of potassium, the chief competing ion in the extraction of cesium. It was confirmed by use of the CSSX model that the higher levels of potassium depress the cesium distribution ratio (DCs), as validated by measurement of DCs values for four of eight specified Hanford waste-simulant compositions. The model predictions were good to an apparent standard error of ±11%. It is concluded from batch distribution experiments, physical-property measurements, equilibrium modeling, flowsheet calculations, and contactor sizing that the CSSX process as currently employed for cesium removal from alkaline salt waste at the SRS is capable of treating similar Hanford tank feeds. For the most challenging waste composition, 41 stages would be required to provide a cesium decontamination factor (DF) of 5000 and a concentration factor (CF) of 5. Commercial contacting equipment with rotor diameters of 10 in. for extraction and 5 in. for stripping should have the capacity to meet throughput requirements, but testing will be required to confirm that the needed efficiency and hydraulic performance are actually obtainable. Markedly improved flowsheet performance was calculated for a new solvent formulation employing the more soluble cesium extractant BEHBCalixC6 used with alternative scrub and strip solutions, respectively 0.1 M NaOH and 10 mM boric acid. The improved system can meet minimum requirements (DF = 5000 and CF = 5) with 17 stages or more ambitious goals (DF = 40,000 and CF = 15) with 19 stages. Potential benefits of further research and development are identified that would lead to reduced costs, greater

  5. Nuclear model parameter testing for nuclear data evaluation (Reference Input Parameter Library: Phase II). Summary report of the third research co-ordination meeting

    International Nuclear Information System (INIS)

    Herman, M.

    2002-04-01

    This report summarises the results and recommendations of the third Research Co-ordination Meeting on improving and testing the Reference Input Parameter Library: Phase II. A primary aim of the meeting was to review the achievements of the CRP, to assess the testing of the library and to approve the final contents. Actions were approved that will result in completion of the file and a draft report by the end of February 2002. Full release of the library is scheduled for July 2002. (author)

  6. Cardiac autonomic modulation induced by doxorubicin in a rodent model of colorectal cancer and the influence of fullerenol pretreatment.

    Directory of Open Access Journals (Sweden)

    Nejka Potočnik

    Full Text Available The very effective anticancer drug doxorubicin (DOX is known to have cardiotoxic side effects, which could be accompanied by autonomic modulation. Autonomic disbalance might even be an initiating mechanism underlying DOX-induced cardiotoxicity and can be studied noninvasively by the analysis of heart rate variability (HRV. A number of strategies have been assessed to predict chemotherapy-induced cardiac dysfunction while HRV, a potential detecting tool, has not yet been tested. Thus, we aimed to determine the effect of DOX treatment on HRV in a rat model of colorectal cancer. While pretreatment with fullerenol (Frl acts protectively on DOX-induced cardiotoxicity, we aimed to test the effect of Frl pretreatment on DOX-induced HRV alterations. After the induction of colorectal cancer, adult male Wistar rats were treated with saline (n = 7, DOX (1.5 mg/kg per week, n = 7 or DOX after pretreatment with Frl (25 mg/kg per week, n = 7 for three weeks (cumulative DOX dose 4.5 mg/kg. One week after treatment rats were anaesthetized, standard ECG was measured and HRV was analyzed in time and frequency domain. During autopsy the intestines and hearts were gathered for biochemical analysis and histopathological examination. DOX treatment significantly decreased parasympathetically mediated high-frequency component (p<0.05 and increased the low-frequency component of HRV (p<0.05, resulting in an increased LF/HF ratio (p<0.05 in cancerous rats. When pretreated with Frl, DOX-induced HRV alterations were prevented: the high-frequency component of HRV increased (p<0.01, the low-frequency decreased (p<0.01, LF/HF ratio decreased consequently (p<0.01 compared to DOX only treatment. In all DOX-treated animals, disbalance of oxidative status in heart tissue and early myocardial lesions were found and were significantly reduced in rats receiving Frl pretreatment. Autonomic modulation accompanied the development of DOX-induced cardiotoxicity in rat model of colorectal

  7. Synthesis, Modelling and Evaluation of Pretreatment Technologies for Biofuels Production Systems

    DEFF Research Database (Denmark)

    Rodrigues Gurgel da Silva, Andrè

    2017-01-01

    was developed for process synthesis of a second generation bioethanol production process. The methodology was used to generate a set of alternatives for organosolv and ammonia fiber explosion (AFEX) pretreatment methods, and to evaluate hotspots in the systems for enhanced and more integrated setups....

  8. Analysis of Ordinal Categorical Data

    CERN Document Server

    Agresti, Alan

    2012-01-01

    Statistical science's first coordinated manual of methods for analyzing ordered categorical data, now fully revised and updated, continues to present applications and case studies in fields as diverse as sociology, public health, ecology, marketing, and pharmacy. Analysis of Ordinal Categorical Data, Second Edition provides an introduction to basic descriptive and inferential methods for categorical data, giving thorough coverage of new developments and recent methods. Special emphasis is placed on interpretation and application of methods including an integrated comparison of the available st

  9. Preference score of units in the presence of ordinal data

    International Nuclear Information System (INIS)

    Jahanshahloo, G.R.; Soleimani-damaneh, M.; Mostafaee, A.

    2009-01-01

    This study deals with the ordinal data in the performance analysis framework and provides a weight-restricted DEA model to obtain the preference score of each unit under assessment. The obtained scores are used to rank DMUs. Furthermore, to decrease the complexity of the provided model, the number of the constraints is decreased by some linear transformations

  10. ADM1-based modeling of anaerobic digestion of swine manure fibers pretreated with aqueous ammonia soaking

    OpenAIRE

    Jurado, Esperanza; Gavala, Hariklia N.; Skiadas, Ioannis

    2012-01-01

    Anaerobic digestion of manure fibers present challenges due to their low biodegradability. Aqueous ammonia soaking (AAS) and subsequent ammonia removal has been tested as a simple and cheap method to disrupt the lignocellulose and increase the methane potential and the biogas productivity of manure fibers. In the present study, mesophilic anaerobic digestion of AAS pretreated manure fibers was tested in CSTR-type digesters fed with swine manure and/or a mixture of swine manure and AAS pretrea...

  11. Radiative transfer modelling in combusting systems using discrete ordinates method on three-dimensional unstructured grids; Modelisation des transferts radiatifs en combustion par methode aux ordonnees discretes sur des maillages non structures tridimensionnels

    Energy Technology Data Exchange (ETDEWEB)

    Joseph, D.

    2004-04-01

    The prediction of pollutant species such as soots and NO{sub x} emissions and lifetime of the walls in a combustion chamber is strongly dependant on heat transfer by radiation at high temperatures. This work deals with the development of a code based on the Discrete Ordinates Method (DOM) aiming at providing radiative source terms and wall fluxes with a good compromise between cpu time and accuracy. Radiative heat transfers are calculated using the unstructured grids defined by the Computational Fluid Dynamics (CFD) codes. The spectral properties of the combustion gases are taken into account by a statistical narrow bands correlated-k model (SNB-ck). Various types of angular quadrature are tested and three different spatial differencing schemes were integrated and compared. The validation tests show the limit at strong optical thicknesses of the finite volume approximation used the Discrete Ordinates Method. The first calculations performed on LES solutions are presented, it provides instantaneous radiative source terms and wall heat fluxes. Those results represent a first step towards radiation/combustion coupling. (author)

  12. Co-ordination of heterovalent cation impurities in molten salts

    International Nuclear Information System (INIS)

    Andreoni, W.; Rovere, M.; Tosi, M.P.

    1982-01-01

    The local liquid structure around heterovalent cation impurities in molten chlorides is discussed in relation to spectroscopic data on solutions of transition metal ions. A tightly packed, low co-ordination shell is shown to be favoured by Coulomb ionic interactions for physically reasonable values of the size of the impurity. A competition between these forces and ''crystal field'' interactions favouring octahedral co-ordination is thus to be expected for many transition metal ions, as suggested by Gruen and McBeth. The transition observed for some transition metal ions from higher to lower co-ordination with increasing temperature is attributed primarily to entropy differences, that are roughly estimated in a solid-like model. (author)

  13. Effect and Modeling of Glucose Inhibition and In Situ Glucose Removal During Enzymatic Hydrolysis of Pretreated Wheat Straw

    DEFF Research Database (Denmark)

    Andric, Pavle; Meyer, Anne S.; Jensen, Peter Arendt

    2010-01-01

    The enzymatic hydrolysis of lignocellulosic biomass is known to be product-inhibited by glucose. In this study, the effects on cellulolytic glucose yields of glucose inhibition and in situ glucose removal were examined and modeled during extended treatment of heat-pretreated wheat straw with the ......The enzymatic hydrolysis of lignocellulosic biomass is known to be product-inhibited by glucose. In this study, the effects on cellulolytic glucose yields of glucose inhibition and in situ glucose removal were examined and modeled during extended treatment of heat-pretreated wheat straw...... with the cellulolytic enzyme system, Celluclast (R) 1.5 L, from Trichoderma reesei, supplemented with a beta-glucosidase, Novozym (R) 188, from Aspergillus niger. Addition of glucose (0-40 g/L) significantly decreased the enzyme-catalyzed glucose formation rates and final glucose yields, in a dose-dependent manner......-Menten inhibition models without great significance of the inhibition mechanism. Moreover, the experimental in situ removal of glucose could be simulated by a Michaelis-Menten inhibition model. The data provide an important base for design of novel reactors and operating regimes which include continuous product...

  14. Quantization in rotating co-ordinates revisited

    International Nuclear Information System (INIS)

    Hussain, F.; Qadir, A.

    1982-07-01

    Recent work on quantization in rotating co-ordinates showed that no radiation would be seen by an observer rotating with a constant angular speed. This work used a Galilean-type co-ordinate transformation. We show that the same result holds for a Lorentz-type co-ordinate system, in spite of the fact that the metric has a co-ordinate singularity at rΩ = 1. Further, we are able to define positive and negative energy modes for a particular case of a non-static, non-stationary metric. (author)

  15. Fuel modelling at extended burnup. Report of the co-ordinated research programme on fuel modelling at extended burnup - FUMEX 1993-1996

    International Nuclear Information System (INIS)

    1998-01-01

    This report provides a description of the experiments chosen, an overview of the codes used by participants in the exercise, and the improvements implemented as a consequence of FUMEX. A commentary is given regarding the various aspects of fuel behavior tested and a detailed quantitative comparison is made between experimental data and code predictions. The report concludes with a discussion of the main findings of the exercise, the identified improvements and shortcomings in codes and modelling, and outstanding technical issues that require further attention

  16. Butyrate pretreatment attenuates heart depression in a mice model of endotoxin-induced sepsis via anti-inflammation and anti-oxidation.

    Science.gov (United States)

    Wang, Fangyan; Jin, Zengyou; Shen, Kaiyi; Weng, Tingting; Chen, Zhisong; Feng, Jiahui; Zhang, Zhengzheng; Liu, Jiaming; Zhang, Xiaolong; Chu, Maoping

    2017-03-01

    The depressed heart function is the main complication to cause death of septic patients in clinic. It is urgent to find effective interventions for this intractable disease. In this study, we investigated whether butyrate could be protective for heart against sepsis and the underlying mechanism. Mice were randomly divided into three groups. Model group challenged with LPS (30 mg/kg, i.p.) only. Butyrate group received butyrate (200 mg/kg·d) for 3days prior to LPS administration (30 mg/kg). Normal group received saline only. 6h and 12h after LPS administration were chosen for detection the parameters to estimate the effects or mechanism of butyrate pretreatment on heart of sepsis. The data showed that septic heart depression was attenuated by butyrate pretreatment through improvement of heart function depression (Pbutyrate pretreatment (Pbutyrate pretreatment (Pbutyrate attenuated septic heart depression via anti-inflammation and anti-oxidation. Copyright © 2016 Elsevier Inc. All rights reserved.

  17. Space in Numerical and Ordinal Information: A Common Construct?

    Directory of Open Access Journals (Sweden)

    Philipp Alexander Schroeder

    2017-12-01

    Full Text Available Space is markedly involved in numerical processing, both explicitly in instrumental learning and implicitly in mental operations on numbers. Besides action decisions, action generations, and attention, the response-related effect of numerical magnitude or ordinality on space is well documented in the Spatial-Numerical Associations of Response Codes (SNARC effect. Here, right- over left-hand responses become relatively faster with increasing magnitude positions. However, SNARC-like behavioral signatures in non-numerical tasks with ordinal information were also observed and inspired new models integrating seemingly spatial effects of ordinal and numerical metrics. To examine this issue further, we report a comparison between numerical SNARC and ordinal SNARC-like effects to investigate group-level characteristics and individual-level deductions from generalized views, i.e., convergent validity. Participants solved order-relevant (before/after classification and order-irrelevant tasks (font color classification with numerical stimuli 1-5, comprising both magnitude and order information, and with weekday stimuli, comprising only ordinal information. A small correlation between magnitude- and order-related SNARCs was observed, but effects are not pronounced in order-irrelevant color judgments. On the group level, order-relevant spatial-numerical associations were best accounted for by a linear magnitude predictor, whereas the SNARC effect for weekdays was categorical. Limited by the representativeness of these tasks and analyses, results are inconsistent with a single amodal cognitive mechanism that activates space in mental processing of cardinal and ordinal information alike. A possible resolution to maintain a generalized view is proposed by discriminating different spatial activations, possibly mediated by visuospatial and verbal working memory, and by relating results to findings from embodied numerical cognition.

  18. Global modeling of Hanford tank waste pretreatment alternatives within a total cleanup system using ASPEN PLUS trademark

    International Nuclear Information System (INIS)

    Knutson, B.J.; Jansen, G. Jr.; Zimmerman, B.D.; Niccoli, L.G.; Lauerhass, L.

    1994-11-01

    The purpose of this work is to evaluate and compare radionuclide separations/processing technologies being developed or considered as Hanford tank waste pretreatment alternatives. These technologies are integrated into a total cleanup system that includes tank waste retrieval, treatment, and disposal. Current Hanford flowsheets typically include only mature, developed technologies, not new technologies. Thus, this work examines the impact/benefits of inserting new technologies into Hanford flowsheets. Waste treatment must produce disposal fractions which are less troublesome than the original material. Researchers seeking effective treatment methods may lack the tools or expertise to fully understand the implications of their approach in terms of secondary and tertiary waste streams or the extent to which a unique new process will affect upstream or downstream processes. This work has developed and demonstrated mass balance methods that clarify the effect of including individual processes in an integrated waste treatment system, such as the Hanford cleanup system. The methods provide a measure of treatment effectiveness and a format for the researcher to understand waste stream interrelationships and determine how a particular treatment technology can best be used in a cleanup system. A description of the Hanford tank waste cleanup model developed using the ASPEN PLUS flowsheet simulation tool is given. Important aspects of the modeling approach are discussed along with a description of how performance measures were developed and integrated within the simulation to evaluate and compare various Hanford tank waste pretreatment alternatives

  19. A novel diffusion-biphasic hydrolysis coupled kinetic model for dilute sulfuric acid pretreatment of corn stover.

    Science.gov (United States)

    Chen, Longjian; Zhang, Haiyan; Li, Junbao; Lu, Minsheng; Guo, Xiaomiao; Han, Lujia

    2015-02-01

    Kinetic experiments on the dilute sulfuric acid pretreatment of corn stover were performed. A high xylan removal and a low inhibitor concentration were achieved by acid pretreatment. A novel diffusion-hydrolysis coupled kinetic model was proposed. The contribution to the xylose yield was analyzed by the kinetic model. Compared with the inhibitor furfural negatively affecting xylose yield, the fast and slow-hydrolyzing xylan significantly contributed to the xylose yield, however, their dominant roles were dependent on reaction temperature and time. The impact of particle size and acid concentration on the xylose yield were also investigated. The diffusion process may significantly influence the hydrolysis of large particles. Increasing the acid concentration from 0.15 M to 0.30 M significantly improved the xylose yield, whereas the extent of improvement decreased to near-quantitative when further increasing acid loading. These findings shed some light on the mechanism for dilute sulfuric acid hydrolysis of corn stover. Copyright © 2014 Elsevier Ltd. All rights reserved.

  20. An approach to solve group-decision-making problems with ordinal interval numbers.

    Science.gov (United States)

    Fan, Zhi-Ping; Liu, Yang

    2010-10-01

    The ordinal interval number is a form of uncertain preference information in group decision making (GDM), while it is seldom discussed in the existing research. This paper investigates how the ranking order of alternatives is determined based on preference information of ordinal interval numbers in GDM problems. When ranking a large quantity of ordinal interval numbers, the efficiency and accuracy of the ranking process are critical. A new approach is proposed to rank alternatives using ordinal interval numbers when every ranking ordinal in an ordinal interval number is thought to be uniformly and independently distributed in its interval. First, we give the definition of possibility degree on comparing two ordinal interval numbers and the related theory analysis. Then, to rank alternatives, by comparing multiple ordinal interval numbers, a collective expectation possibility degree matrix on pairwise comparisons of alternatives is built, and an optimization model based on this matrix is constructed. Furthermore, an algorithm is also presented to rank alternatives by solving the model. Finally, two examples are used to illustrate the use of the proposed approach.

  1. Augmenting Ordinal Methods of Attribute Weight Approximation

    DEFF Research Database (Denmark)

    Daneilson, Mats; Ekenberg, Love; He, Ying

    2014-01-01

    of the obstacles and methods for introducing so-called surrogate weights have proliferated in the form of ordinal ranking methods for criteria weights. Considering the decision quality, one main problem is that the input information allowed in ordinal methods is sometimes too restricted. At the same time, decision...

  2. Atomic Energy Law with ordinances. 9. ed.

    International Nuclear Information System (INIS)

    Anon.

    1982-01-01

    The revised edition of the text is due to a variety of major changes in, and amendments to, the German Atomic Energy Law. This book includes the current version of the Atomic Energy Law which has been changed several times, the 1982-version of the ordinace concerning procedures laid down in the Atomic Energy Law, the 1976 radiation protection ordinance together with recent amendments, the 1973 X-ray ordinance, the 1977 financial security ordinance laid down in the Atomic Energy Law, the 1981 ordinance concerning costs, the ordinance concerning performance in anticipation of ultimate disposal. The book is a compilation of the basic Atomic Energy Law which is needed mostly for imminent practical requirements. (orig./HSCH) [de

  3. The Design Co-ordination Framework: key elements for effective product development

    DEFF Research Database (Denmark)

    Andreasen, Mogens Myrup; Bowen, J.; Storm, T.

    1997-01-01

    This paper proposes a Design Co-ordination Framework (DCF) i.e. a concept for an ideal DC system with the abilities to support co-ordination of various complex aspects of product development. A set of frames, modelling key elements of co-ordination, which reflect the states of design, plans......, organisation, allocations, tasks etc. during the design process, has been identified. Each frame is explained and the co-ordination, i.e. the management of the links between these frames, is presented, based upon characteristic DC situations in Industry. It is concluded that while the DCF provides a basis...... for our research efforts into enhancing the product development process there is still considerable work and development required before it can adequately refelct and support Design Co-ordination....

  4. Economic effect of smoke-free ordinances on 11 Missouri cities.

    Science.gov (United States)

    Kayani, Noaman; Cowan, Stanley R; Homan, Sherri G; Wilson, Janet; Warren, Victoria Fehrmann; Yun, Shumei

    2012-01-01

    The harmful effects of secondhand smoke are convincing more and more communities across the United States and the world to prohibit smoking in public places, especially in eating and drinking establishments. A 1993 Missouri state law allows smoking in designated areas in indoor public places such as restaurants and bars. Consequently, some Missouri communities have adopted local ordinances that prohibit smoking in all indoor workplaces, including restaurants and bars. We used an objective measure of economic activity, the taxable sales revenues of eating and drinking establishments, to empirically examine the economic effect of smoke-free ordinances. We studied the economic effect of smoke-free ordinances in 11 Missouri cities using multivariate log-linear regression models with log-transformed taxable sales revenues of eating and drinking establishments as the dependent variable and the smoke-free ordinance as the independent variable, while controlling for seasonality, economic condition and unemployment. We used data from 20 quarters before the smoke-free ordinances and at least 10 quarters after the smoke-free ordinances for all cities. The null hypothesis of no effect of smoke-free ordinance on taxable sales of the eating and drinking establishments was tested. Eight of the 11 cities had increased taxable sales for eating and drinking establishments postordinance. The remaining 3 experienced no change. The findings of our study are consistent with findings from most published economic studies that a smoke-free ordinance does not harm a local economy.

  5. Xylan hydrolysis in Populus trichocarpa × P. deltoides and model substrates during hydrothermal pretreatment.

    Science.gov (United States)

    Trajano, Heather L; Pattathil, Sivakumar; Tomkins, Bruce A; Tschaplinski, Timothy J; Hahn, Michael G; Van Berkel, Gary J; Wyman, Charles E

    2015-03-01

    Previous studies defined easy and difficult to hydrolyze fractions of hemicellulose that may result from bonds among cellulose, hemicellulose, and lignin. To understand how such bonds affect hydrolysis, Populus trichocarpa × Populus deltoides, holocellulose isolated from P. trichocarpa × P. deltoides and birchwood xylan were subjected to hydrothermal flow-through pretreatment. Samples were characterized by glycome profiling, HPLC, and UPLC-MS. Glycome profiling revealed steady fragmentation and removal of glycans from solids during hydrolysis. The extent of polysaccharide fragmentation, hydrolysis rate, and total xylose yield were lowest for P. trichocarpa × P. deltoides and greatest for birchwood xylan. Comparison of results from P. trichocarpa × P. deltoides and holocellulose suggested that lignin-carbohydrate complexes reduce hydrolysis rates and limit release of large xylooligomers. Smaller differences between results with holocellulose and birchwood xylan suggest xylan-cellulose hydrogen bonds limited hydrolysis, but to a lesser extent. These findings imply cell wall structure strongly influences hydrolysis. Copyright © 2014 Elsevier Ltd. All rights reserved.

  6. The immune response of rainbow trout to Flavobacterium psychrophilum following immersion-challenge model with and without hydrogen peroxide pre-treatment

    DEFF Research Database (Denmark)

    Henriksen, Maya Maria Mihályi; Madsen, Lone; Kania, P. W.

    2013-01-01

    , no commercial vaccine is currently available and the disease is treated with antibiotics. Injection-based challenges with F. psychrophilum are standardized but the route of infection does not reflect a natural situation. Therefore, we established an immersion-based model investigating if hydrogen peroxide (H2O2......) pre-treatment could elevate infection and mortality. The model consisted of four groups: 1) Un-exposed control, 2) H2O2 exposure, 3) F. psychrophilum immersion and 4) H2O2 + F. psychrophilum. Pre-treatment with H2O2 increased mortality two-fold if fish also were exposed to F. psychrophilum after...... and FoxP3. A pro-inflammatory response was indicated, but only a weak indication of an adaptive response was recorded (most evident in the F. psychrophilum group). Further, pre-treatment with H2O2 affected the correlation gene expression and pathogen load in several cases. Morphological changes...

  7. Allegheny County Municipal Land Use Ordinances

    Data.gov (United States)

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — Many municipalities have their own land use ordinances and establish standards and requirements for land use and development in that municipality. This dataset is...

  8. A Characterization of Ordinal Potential Games

    NARCIS (Netherlands)

    Voorneveld, M.; Norde, H.W.

    1996-01-01

    This note characterizes ordinal potential games by the absence of weak improvement cycles and an order condition on the strategy space.This order condition is automatically satisfied if the strategy space is countable.

  9. Overview of Existing Wind Energy Ordinances

    Energy Technology Data Exchange (ETDEWEB)

    Oteri, F.

    2008-12-01

    Due to increased energy demand in the United States, rural communities with limited or no experience with wind energy now have the opportunity to become involved in this industry. Communities with good wind resources may be approached by entities with plans to develop the resource. Although these opportunities can create new revenue in the form of construction jobs and land lease payments, they also create a new responsibility on the part of local governments to ensure that ordinances will be established to aid the development of safe facilities that will be embraced by the community. The purpose of this report is to educate and engage state and local governments, as well as policymakers, about existing large wind energy ordinances. These groups will have a collection of examples to utilize when they attempt to draft a new large wind energy ordinance in a town or county without existing ordinances.

  10. Parameter optimization of ferro-sonication pre-treatment process for degradation of bisphenol A and biodegradation from wastewater sludge using response surface model.

    Science.gov (United States)

    Mohapatra, D P; Brar, S K; Tyagi, R D; Surampalli, R Y

    2011-05-15

    In this study, the application of response surface model in predicting and optimizing the ferro-sonication pre-treatment for degradation of bisphenol A (BPA), an endocrine disrupter compound from wastewater sludge (WWS) was investigated. The ferro-sonication pre-treatment process was carried out according to central composite design (CCD) with four independent variables such as wastewater sludge solids concentration, pH, ultrasonication time and FeSO(4) concentration. The effect of ferro-sonication pre-treatment was assessed in terms of increase in sludge solids (suspended solids (SS) and volatile solids (VS)) and organic matter (chemical oxygen demand (COD) and soluble organic carbon (SOC)) solubilization and simultaneous BPA degradation from WWS. It was observed that among all the variables studied, ultrasonication time had more significantly affected the efficiency of the ferro-sonication pre-treatment process followed by FeSO(4) and solids concentration. Through this optimization process, it was found that maximum BPA degradation of 88% could be obtained with 163 min ultrasonication time, 2.71 mg/L FeSO(4) concentration, pH 2.81 with 22 g/L SS. Further, the effect of ferro-sonication pre-treatment on biodegradation of WWS was also studied. It was observed that ultrasonication time had significant effect and the higher biodegradation (32.48%) was observed at 180 min ultrasonication time. Copyright © 2011 Elsevier B.V. All rights reserved.

  11. Ordinance on the Protection against X-Radiation Hazards (X-Ray Ordinance)

    International Nuclear Information System (INIS)

    1987-01-01

    The ordinance refers to X-ray equipment and to stray radiation sources which generate X-radiation of at least 5 keV by means of accelerated electrons, and for this purpose apply an acceleration energy not exceeding 3 MeV. The ordinance does not apply to stray radiation sources which are used for the generation of ionizing particle radiation and thus are subject to the provisions of the Radiation Protection Ordinance. (orig./PW) [de

  12. Co-ordinating Product Developing Activities

    DEFF Research Database (Denmark)

    Terkelsen, Søren Bendix

    1996-01-01

    The paper contains a presentation of research methods to be used in case studies in product development and a presentation on how to deal with Design Co-ordination according to litterature......The paper contains a presentation of research methods to be used in case studies in product development and a presentation on how to deal with Design Co-ordination according to litterature...

  13. Dimensionality Reduction in Multiple Ordinal Regression.

    Science.gov (United States)

    Zeng, Jiabei; Liu, Yang; Leng, Biao; Xiong, Zhang; Cheung, Yiu-Ming

    2017-10-10

    Supervised dimensionality reduction (DR) plays an important role in learning systems with high-dimensional data. It projects the data into a low-dimensional subspace and keeps the projected data distinguishable in different classes. In addition to preserving the discriminant information for binary or multiple classes, some real-world applications also require keeping the preference degrees of assigning the data to multiple aspects, e.g., to keep the different intensities for co-occurring facial expressions or the product ratings in different aspects. To address this issue, we propose a novel supervised DR method for DR in multiple ordinal regression (DRMOR), whose projected subspace preserves all the ordinal information in multiple aspects or labels. We formulate this problem as a joint optimization framework to simultaneously perform DR and ordinal regression. In contrast to most existing DR methods, which are conducted independently of the subsequent classification or ordinal regression, the proposed framework fully benefits from both of the procedures. We experimentally demonstrate that the proposed DRMOR method (DRMOR-M) well preserves the ordinal information from all the aspects or labels in the learned subspace. Moreover, DRMOR-M exhibits advantages compared with representative DR or ordinal regression algorithms on three standard data sets.

  14. Recent developments in discrete ordinates electron transport

    International Nuclear Information System (INIS)

    Morel, J.E.; Lorence, L.J. Jr.

    1986-01-01

    The discrete ordinates method is a deterministic method for numerically solving the Boltzmann equation. It was originally developed for neutron transport calculations, but is routinely used for photon and coupled neutron-photon transport calculations as well. The computational state of the art for coupled electron-photon transport (CEPT) calculations is not as developed as that for neutron transport calculations. The only production codes currently available for CEPT calculations are condensed-history Monte Carlo codes such as the ETRAN and ITS codes. A deterministic capability for production calculations is clearly needed. In response to this need, we have begun the development of a production discrete ordinates code for CEPT calculations. The purpose of this paper is to describe the basic approach we are taking, discuss the current status of the project, and present some new computational results. Although further characterization of the coupled electron-photon discrete ordinates method remains to be done, the results to date indicate that the discrete ordinates method can be just as accurate and from 10 to 100 times faster than the Monte Carlo method for a wide variety of problems. We stress that these results are obtained with standard discrete ordinates codes such as ONETRAN. It is clear that even greater efficiency can be obtained by developing a new generation of production discrete ordinates codes specifically designed to solve the Boltzmann-Fokker-Planck equation. However, the prospects for such development in the near future appear to be remote

  15. Predicting oropharyngeal tumor volume throughout the course of radiation therapy from pretreatment computed tomography data using general linear models

    International Nuclear Information System (INIS)

    Yock, Adam D.; Kudchadker, Rajat J.; Rao, Arvind; Dong, Lei; Beadle, Beth M.; Garden, Adam S.; Court, Laurence E.

    2014-01-01

    Purpose: The purpose of this work was to develop and evaluate the accuracy of several predictive models of variation in tumor volume throughout the course of radiation therapy. Methods: Nineteen patients with oropharyngeal cancers were imaged daily with CT-on-rails for image-guided alignment per an institutional protocol. The daily volumes of 35 tumors in these 19 patients were determined and used to generate (1) a linear model in which tumor volume changed at a constant rate, (2) a general linear model that utilized the power fit relationship between the daily and initial tumor volumes, and (3) a functional general linear model that identified and exploited the primary modes of variation between time series describing the changing tumor volumes. Primary and nodal tumor volumes were examined separately. The accuracy of these models in predicting daily tumor volumes were compared with those of static and linear reference models using leave-one-out cross-validation. Results: In predicting the daily volume of primary tumors, the general linear model and the functional general linear model were more accurate than the static reference model by 9.9% (range: −11.6%–23.8%) and 14.6% (range: −7.3%–27.5%), respectively, and were more accurate than the linear reference model by 14.2% (range: −6.8%–40.3%) and 13.1% (range: −1.5%–52.5%), respectively. In predicting the daily volume of nodal tumors, only the 14.4% (range: −11.1%–20.5%) improvement in accuracy of the functional general linear model compared to the static reference model was statistically significant. Conclusions: A general linear model and a functional general linear model trained on data from a small population of patients can predict the primary tumor volume throughout the course of radiation therapy with greater accuracy than standard reference models. These more accurate models may increase the prognostic value of information about the tumor garnered from pretreatment computed tomography

  16. Radiation Ordinance 1983 (No. 58 of 1983) (Australian Capital Territory)

    International Nuclear Information System (INIS)

    1983-01-01

    This Ordinance provides for the safe use, transportation and disposal of radioactive materials and irradiating apparatus. It repeals the Fluoroscopes Ordinance of 1958. Radioactive materials whose radioactivity does not exceed levels as set out in a Schedule to the Ordinance are exempted from application of the Ordinance. (NEA) [fr

  17. Biosorption of uranium(VI) from aqueous solutions by Ca-pretreated Cystoseira indica alga: breakthrough curves studies and modeling.

    Science.gov (United States)

    Ghasemi, Morteza; Keshtkar, Ali Reza; Dabbagh, Reza; Jaber Safdari, S

    2011-05-15

    Uranium(VI) biosorption from aqueous solutions containing 60 mg l(-1) metal concentration by Ca-pretreated Cystoseira indica alga was studied in a packed bed column with 1.5 cm internal diameter. The effect of bed height and flow rate on biosorption process was investigated and the experimental breakthrough curves were obtained. Results showed that by increasing the bed height, the breakthrough and exhaustion times increased and the slope of breakthrough curves decreased. Also, it was observed that the controlled-rate step shifted from external to internal mass transfer limitations, as the flow rate increased. The maximum uptake capacity, 318.15 mg g(-1), and total metal removal, 59.32%, were obtained at flow rate of 2.3 ml min(-1) and bed height of 6 cm. The column was regenerated using 0.1M HCl solution and sorption-desorption studies were carried out for three cycles. The obtained results confirmed that reusability of this biosorbent is possible. The results obtained agreed well with the bed depth service time model. In addition, for estimations of the parameters necessary for the design of a large-scale packed bed column, the experimental data were also fitted to the Thomas, Yan and Belter models and were found to agree with the experimental data fairly well. Copyright © 2011 Elsevier B.V. All rights reserved.

  18. Biosorption of uranium(VI) from aqueous solutions by Ca-pretreated Cystoseira indica alga: Breakthrough curves studies and modeling

    Energy Technology Data Exchange (ETDEWEB)

    Ghasemi, Morteza [Faculty of Nuclear Engineering, Shahid Beheshti University, Tehran (Iran, Islamic Republic of); Keshtkar, Ali Reza, E-mail: akeshtkar@aeoi.org.ir [Nuclear Fuel Cycle School, Nuclear Science and Technology Research Institute, Tehran (Iran, Islamic Republic of); Dabbagh, Reza [Nuclear Science Research School, Nuclear Science and Technology Research Institute, Tehran (Iran, Islamic Republic of); Jaber Safdari, S. [Nuclear Fuel Cycle School, Nuclear Science and Technology Research Institute, Tehran (Iran, Islamic Republic of)

    2011-05-15

    Uranium(VI) biosorption from aqueous solutions containing 60 mg l{sup -1} metal concentration by Ca-pretreated Cystoseira indica alga was studied in a packed bed column with 1.5 cm internal diameter. The effect of bed height and flow rate on biosorption process was investigated and the experimental breakthrough curves were obtained. Results showed that by increasing the bed height, the breakthrough and exhaustion times increased and the slope of breakthrough curves decreased. Also, it was observed that the controlled-rate step shifted from external to internal mass transfer limitations, as the flow rate increased. The maximum uptake capacity, 318.15 mg g{sup -1}, and total metal removal, 59.32%, were obtained at flow rate of 2.3 ml min{sup -1} and bed height of 6 cm. The column was regenerated using 0.1 M HCl solution and sorption-desorption studies were carried out for three cycles. The obtained results confirmed that reusability of this biosorbent is possible. The results obtained agreed well with the bed depth service time model. In addition, for estimations of the parameters necessary for the design of a large-scale packed bed column, the experimental data were also fitted to the Thomas, Yan and Belter models and were found to agree with the experimental data fairly well.

  19. Pretreatment of Acacia nilotica Sawdust by Catalytic Delignification and Its Fractal Kinetic Modeling

    Science.gov (United States)

    Mallick, Abhyuday; Ash, Soumendra Nath; Mahapatra, Debashis Kumar

    2016-04-01

    Alkaline delignification of Acacia nilotica heartwood has been carried out using 10 % Sodium hydroxide and Sodium sulphide as the cooking liquor. Delignification was carried out at 373, 393, 403 and 413 K on Acacia nilotica sawdust of particle-sizes 70, 100 and 120 mesh, for durations ranging from 1 to 3 h. The reactions were carried out in presence and in absence of Ferrous sulphate to determine its catalytic properties in delignification. Maximum delignification achieved was 82.7 %, based on Klason lignin, in 3 h at 413 K for 120 mesh feed. The activation energies for delignification were 20.9275 and 35 kJ/mol, respectively, in presence and in absence of Ferrous sulphate, indicating its significant catalytic effect. A kinetic model for delignification was developed by modification of the Nuclei Growth model. Delignification extent could be predicted from the developed model quite accurately, with R2 values ranging from 0.947 to 0.99.

  20. The new German radiation protection ordinance

    International Nuclear Information System (INIS)

    Pfeffer, W.; Weimer, G.

    2003-01-01

    According to European law, the Basic Safety Standards (BSS) published by the European Council in 1996 and the Council Directive on health protection of individuals against dangers of ionising radiation in relation to medical exposure had to be transferred into national law within due time. In 2001 the new Ordinance for the Implementation of the Euratom Guidelines on Radiation Protection] was published, which replaces the old Radiation Protection Ordinance. The new German Ordinance adapts the European Directive to German law, covering the general principles but even giving more details in many fields of radiation protection. The BSS scope certainly is much broader than the prescriptions important for the field of radiation protection in nuclear power plants. According to the scope of this workshop on occupational exposure in nuclear power plants - and as the BSS most probably will be quite familiar to all of you - after a short general overview on relevant contents of the German Ordinance, this presentation will focus on the main issues important in the operation of NPP and especially on some areas which may give rise to necessary changes caused by the new Ordinance. (A.L.B.)

  1. Contributory fault and level of personal injury to drivers involved in head-on collisions: Application of copula-based bivariate ordinal models.

    Science.gov (United States)

    Wali, Behram; Khattak, Asad J; Xu, Jingjing

    2018-01-01

    The main objective of this study is to simultaneously investigate the degree of injury severity sustained by drivers involved in head-on collisions with respect to fault status designation. This is complicated to answer due to many issues, one of which is the potential presence of correlation between injury outcomes of drivers involved in the same head-on collision. To address this concern, we present seemingly unrelated bivariate ordered response models by analyzing the joint injury severity probability distribution of at-fault and not-at-fault drivers. Moreover, the assumption of bivariate normality of residuals and the linear form of stochastic dependence implied by such models may be unduly restrictive. To test this, Archimedean copula structures and normal mixture marginals are integrated into the joint estimation framework, which can characterize complex forms of stochastic dependencies and non-normality in residual terms. The models are estimated using 2013 Virginia police reported two-vehicle head-on collision data, where exactly one driver is at-fault. The results suggest that both at-fault and not-at-fault drivers sustained serious/fatal injuries in 8% of crashes, whereas, in 4% of the cases, the not-at-fault driver sustained a serious/fatal injury with no injury to the at-fault driver at all. Furthermore, if the at-fault driver is fatigued, apparently asleep, or has been drinking the not-at-fault driver is more likely to sustain a severe/fatal injury, controlling for other factors and potential correlations between the injury outcomes. While not-at-fault vehicle speed affects injury severity of at-fault driver, the effect is smaller than the effect of at-fault vehicle speed on at-fault injury outcome. Contrarily, and importantly, the effect of at-fault vehicle speed on injury severity of not-at-fault driver is almost equal to the effect of not-at-fault vehicle speed on injury outcome of not-at-fault driver. Compared to traditional ordered probability

  2. Pretreatment chemistry for dual media filtration: model simulations and experimental studies.

    Science.gov (United States)

    Shin, J Y; O'Melia, C R

    2006-01-01

    Laboratory dual media filtration experiments were conducted (a) in direct filtration mode using model raw water moderate in turbidity and low in DOC, and (b) in conventional filtration mode treating water moderate in turbidity and high in DOC. Model simulations of filter performance for the removal of particles provided hypotheses for the experimental studies of dual media filtration. An increase in alum dose in direct filtration mode, while improving filter performance, also showed some disadvantages, including rapid development of head loss. Suboptimal dose in direct filtration significantly impaired the filter performance. In conventional mode, the effect of alum dose on the filter performance, while obvious, was not as dramatic as in direct filtration. Ripening indicated by particle counts occurred earlier than by turbidity and breakthrough of particle counts started earlier than breakthrough of turbidity, suggesting that turbidity can be used as a more conservative monitor of filter performance during the ripening period to minimise the risk of passage of small particles, while particle counts can be considered a more sensitive indicator of deteriorating filter performance during the breakthrough period. The lower sand layer served as a multiple barrier for particle when the performance of the anthracite layer was not effective.

  3. Ozonisation of model compounds as a pretreatment step for the biological wastewater treatment

    International Nuclear Information System (INIS)

    Degen, U.

    1979-11-01

    Biological degradability and toxicity of organic substances are two basic criteria determining their behaviour in natural environment and during the biological treatment of waste waters. In this work oxidation products of model compounds (p-toluenesulfonic acid, benzenesulfonic acid and aniline) generated by ozonation were tested in a two step laboratory plant with activated sludge. The organic oxidation products and the initial compounds were the sole source of carbon for the microbes of the adapted activated sludge. The progress of elimination of the compounds was studied by measuring DOC, COD, UV-spectra of the initial compounds and sulfate. Initial concentrations of the model compounds were 2-4 mmole/1 with 25-75ion of sulfonic acids. As oxidation products of p-toluenesulfonic acid the following compounds were identified and quantitatively measured: methylglyoxal, pyruvic acid, oxalic acid, acetic acid, formic acid and sulfate. With all the various solutions with different concentrations of initial compounds and oxidation products the biological activity in the two step laboratory plant could maintain. p-Toluenesulfonic acid and the oxidation products are biologically degraded. The degradation of p-toluenesulfonic acid is measured by following the increasing of the sulfate concentration after biological treatment. This shows that the elimination of p-toluenesulfonic acid is not an adsorption but a mineralization step. At high p-toluenesulfonic acid concentration and low concentration of oxidation products p-toluenesulfonic acid is eliminated with a high efficiency (4.3 mole/d m 3 = 0.34 kg p-toluenesulfonic acid/d m 3 ). However at high concentration of oxidation products p-toluenesulfonic acid is less degraded. The oxidation products are always degraded with an elimination efficiency of 70%. A high load of biologically degradable oxidation products diminished the elimination efficiency of p-toluenesulfonic acid. (orig.) [de

  4. Multidimensional electron-photon transport with standard discrete ordinates codes

    International Nuclear Information System (INIS)

    Drumm, C.R.

    1997-01-01

    A method is described for generating electron cross sections that are comparable with standard discrete ordinates codes without modification. There are many advantages of using an established discrete ordinates solver, e.g. immediately available adjoint capability. Coupled electron-photon transport capability is needed for many applications, including the modeling of the response of electronics components to space and man-made radiation environments. The cross sections have been successfully used in the DORT, TWODANT and TORT discrete ordinates codes. The cross sections are shown to provide accurate and efficient solutions to certain multidimensional electron-photon transport problems. The key to the method is a simultaneous solution of the continuous-slowing-down (CSD) portion and elastic-scattering portion of the scattering source by the Goudsmit-Saunderson theory. The resulting multigroup-Legendre cross sections are much smaller than the true scattering cross sections that they represent. Under certain conditions, the cross sections are guaranteed positive and converge with a low-order Legendre expansion

  5. Multidimensional electron-photon transport with standard discrete ordinates codes

    International Nuclear Information System (INIS)

    Drumm, C.R.

    1997-01-01

    A method is described for generating electron cross sections that are compatible with standard discrete ordinates codes without modification. There are many advantages to using an established discrete ordinates solver, e.g., immediately available adjoint capability. Coupled electron-photon transport capability is needed for many applications, including the modeling of the response of electronics components to space and synthetic radiation environments. The cross sections have been successfully used in the DORT, TWODANT, and TORT discrete ordinates codes. The cross sections are shown to provide accurate and efficient solutions to certain multidimensional electron-photon transport problems. The key to the method is a simultaneous solution of the continuous-slowing-down and elastic-scattering portions of the scattering source by the Goudsmit-Saunderson theory. The resulting multigroup-Legendre cross sections are much smaller than the true scattering cross sections that they represent. Under certain conditions, the cross sections are guaranteed positive and converge with a low-order Legendre expansion

  6. Calculation of neutron shielding using an unidimensional model of transportation in formulation of discrete ordinates with scattering linearly anisotropic and a speed

    International Nuclear Information System (INIS)

    Libotte, Rafael Barbosa; Alves Filho, Hermes; Oliva, Amaury Muñoz

    2017-01-01

    The physical phenomenon of transport of neutral particles in a host environment is of interest in various scientific applications, e.g., nuclear reactors, shielding calculations, radiological protection, nuclear medicine, agronomy, materials science, oil prospecting, etc. In all these areas there is a need for an accurate description of the transport of the particles in the host medium. In this class of applications are the neutron shielding problems, also referred to as 'fixed-source' problems, where the interaction of the particles with the medium does not produce new neutrons, i.e., non-multiplicative medium. In this context, the development of tools that model these problems is relevant and of a beneficial return to society. In this work, we propose the development of deterministic mathematical and computational modeling of neutron transport using the linearized equation of Boltzmann applied to neutron shielding problems. Here we present also the development of a spectro-nodal method (coarse mesh) considering the scattering phenomenon as being linearly anisotropic. We show the results using a computational application, developed in Java language, version 1.8.0 9 1

  7. Limited memory Broyden-Fletcher-Goldfarb-Shanno (L-BFGS) method for the parameter estimation on geographically weighted ordinal logistic regression model (GWOLR)

    Science.gov (United States)

    Saputro, Dewi Retno Sari; Widyaningsih, Purnami

    2017-08-01

    In general, the parameter estimation of GWOLR model uses maximum likelihood method, but it constructs a system of nonlinear equations, making it difficult to find the solution. Therefore, an approximate solution is needed. There are two popular numerical methods: the methods of Newton and Quasi-Newton (QN). Newton's method requires large-scale time in executing the computation program since it contains Jacobian matrix (derivative). QN method overcomes the drawback of Newton's method by substituting derivative computation into a function of direct computation. The QN method uses Hessian matrix approach which contains Davidon-Fletcher-Powell (DFP) formula. The Broyden-Fletcher-Goldfarb-Shanno (BFGS) method is categorized as the QN method which has the DFP formula attribute of having positive definite Hessian matrix. The BFGS method requires large memory in executing the program so another algorithm to decrease memory usage is needed, namely Low Memory BFGS (LBFGS). The purpose of this research is to compute the efficiency of the LBFGS method in the iterative and recursive computation of Hessian matrix and its inverse for the GWOLR parameter estimation. In reference to the research findings, we found out that the BFGS and LBFGS methods have arithmetic operation schemes, including O(n2) and O(nm).

  8. Emission model for landfills with mechanically-biologically pretreated waste, with the emphasis on modelling the gas balance; Emissionsprognosemodell fuer Deponien mit mechanisch-biologisch vorbehandelten Abfaellen - Schwerpunkt: Modellierung des Gashaushaltes

    Energy Technology Data Exchange (ETDEWEB)

    Danhamer, H.

    2001-07-01

    The objective of this work was to determine influence factors on processes going on in landfills with mechanically-biologically pretreated waste (MBP-landfills) in order to predict emissions. For this purpose a computer based model has been developed. The model allows to simulate the gas, water and heat balance as well as settlement processes and was called DESIM2005 (version MB). It is based on theoretical modeling approaches as well as data from lab and reactor experiments. The main focus of model application was to determine factors influencing the gas phase and the emissions of landfill gas and methane during operation and aftercare of MBP-landfills. By performing simulations the effects of changing parameters for the processes gas transport and biological degradation as well as the effects of different qualities in waste pretreatment and of varying landfill operation techniques were investigated. Possibilities for increasing the environmental sustainability of landfills containing mechanically-biologically pretreated waste were shown. (orig.)

  9. In vivo pretreatment of Eudrilus eugeniae powder attenuates β-adrenoceptor toxicity mediated by isoproterenol in rat model

    OpenAIRE

    Jaganathan Anitha; Kadarkarai Murugan; Akon Higuchi; Abdullah A. Alarfaj; Murugan A. Munusamy; Giovanni Benelli

    2016-01-01

    The present study was designed to discover the potential cardioprotective function of earthworm powder (EWP) extracted from Eudrilus eugeniae on isoproterenol (ISO)-induced myocardial infarction in male Wistar rats. The rats were divided into four groups, with six rats in each group. Certain rats were pretreated with EWP (200 mg/kg bwt) (Group III), and a myocardial infarction was then induced by subcutaneous injection of ISO (85 mg/kg bwt) (Group II). Oral pretreatment of 200 mg/kg bwt of EW...

  10. INFCE technical co-ordinating committee documents

    International Nuclear Information System (INIS)

    A collection of the documents covering the period December 1977 through February 1980 submitted to or generated by the Technical Co-ordinating Comittee is presented. The documents cover primarily the organizational aspects of INFCE, but conclusions from the various Working Trays are summarized

  11. An approximate marginal logistic distribution for the analysis of longitudinal ordinal data

    NARCIS (Netherlands)

    Nooraee, Nazanin; Abegaz, Fentaw; Ormel, Johan; Wit, Ernst; van den Heuvel, Edwin R

    Subject-specific and marginal models have been developed for the analysis of longitudinal ordinal data. Subject-specific models often lack a population-average interpretation of the model parameters due to the conditional formulation of random intercepts and slopes. Marginal models frequently lack

  12. Biomimetic cell wall model studies to identify new lignin bioengineering targets for improving biomass susceptibility to pretreatment and enzymatic saccharification

    Science.gov (United States)

    Increasingly, bioengineering of lignin to contain atypical building blocks from other metabolic pathways is being pursued to custom-design lignin that is easier to remove by chemical pretreatments and less inhibitory toward polysaccharide saccharification. Because plants produce such a diverse array...

  13. Continuous anaerobic digestion of swine manure: ADM1-based modelling and effect of addition of swine manure fibers pretreated with aqueous ammonia soaking

    DEFF Research Database (Denmark)

    Jurado, E.; Antonopoulou, G.; Lyberatos, G.

    2016-01-01

    Anaerobic digestion of manure fibers presents challenges due to their low biodegradability. Aqueous ammonia soaking (AAS) has been tested as a simple method to disrupt the lignocellulose and increase the methane yield of manure fibers. In the present study, mesophilic anaerobic digestion of AAS...... pretreated manure fibers was performed in CSTR-type digesters, fed with swine manure and/or a mixtureof swine manure and AAS pretreated manure fibers (at a total solids based ratio of 0.52 manure per0.48 fibers). Two different simulations were performed. In the first place, the Anaerobic Digestion Model 1...... (ADM1) was fitted to a manure-fed, CSTR-type digester and validated by simulating the performance of a second reactor digesting manure. It was shown that disintegration and hydrolysis of the solid matter of manure was such a slow process that the organic particulate matter did not significantly...

  14. 75 FR 23280 - Choctaw Nation of Oklahoma Alcohol Control Ordinance

    Science.gov (United States)

    2010-05-03

    ... ORDINANCE ARTICLE I. INTRODUCTION. Section 1.1. Title. This Ordinance shall be known as the ``Choctaw Nation.... Application of Federal Law. Federal law forbids the introduction, possession, and sale of liquor in Indian... Time. Unless otherwise provided in this Ordinance, in computing any period of time prescribed or...

  15. Rain Scattering and Co-ordinate Distance Calculation

    Directory of Open Access Journals (Sweden)

    M. Hajny

    1998-12-01

    Full Text Available Calculations of scattered field on the rain objects are based on using of Multiple MultiPole (MMP numerical method. Both bi-static scattering function and bi-static scattering cross section are calculated in the plane parallel to Earth surface. The co-ordination area was determined using the simple model of scattering volume [1]. Calculation for frequency 9.595 GHz and antenna elevation of 25° was done. Obtained results are compared with calculation in accordance to ITU-R recommendation.

  16. Pretreatment with Shuanghe-Tang Extract Attenuates Postischemic Brain Injury and Edema in a Mouse Model of Stroke: An Analysis of Medicinal Herbs Listed in Dongui Bogam

    Directory of Open Access Journals (Sweden)

    Min Jae Kim

    2018-01-01

    Full Text Available Aim. Although stroke is among the leading causes of death and long-term disability, there are few effective treatments for limiting the severity of neurological sequelae. We evaluated the effects of 29 medicinal herbs listed in the Pung chapter of the 17th century Korean medical text Dongui Bogam on stroke symptoms in a mouse model of cerebral ischemia. Methods. Focal cerebral ischemia was induced via photothrombosis. Infarct volume, brain edema, and neurological deficits were evaluated. Immunofluorescence staining for tight junction proteins and aquaporin 4 (AQP4 was performed following ischemic injury. Results. Based on our initial findings, we examined the effects of two prescriptions in which the candidate herbs comprised more than 60% of the total formula: Shuanghe-tang and Zengsunsiwu-tang. Pretreatment with Shuanghe-tang significantly reduced infarct volume, decreased blood-brain barrier (BBB breakdown, attenuated edema, and improved neurological and motor functions in a dose-dependent manner (30, 100, and 300 mg/kg, while no such effects were observed in mice pretreated with Zengsunsiwu-tang. Immunohistochemical analysis revealed significant increases in ipsilateral occludin and zonula occludens 1 (ZO-1 expression in Shuanghe-tang-pretreated mice, as well as increased AQP4 immunofluorescence. Conclusions. These results indicate that Shuanghe-tang may protect against brain injury and promote recovery of neurological function following ischemia.

  17. Perineural pretreatment of bee venom attenuated the development of allodynia in the spinal nerve ligation injured neuropathic pain model; an experimental study.

    Science.gov (United States)

    Koh, Won Uk; Choi, Seong Soo; Lee, Jong Hyuk; Lee, So Hee; Lee, Sun Kyung; Lee, Yoon Kyung; Leem, Jeong Gil; Song, Jun Gol; Shin, Jin Woo

    2014-11-04

    Diluted bee venom (BV) is known to have anti-nociceptive and anti-inflammatory effects. We therefore assessed whether perineural bee venom pretreatment could attenuate the development of neuropathic pain in the spinal nerve ligation injured animal model. Neuropathic pain was surgically induced in 30 male Sprague Dawley rats by ligation of the L5 and L6 spinal nerves, with 10 rats each treated with saline and 0.05 and 0.1 mg BV. Behavioral testing for mechanical, cold, and thermal allodynia was conducted on postoperative days 3 to 29. Three rats in each group and 9 sham operated rats were sacrificed on day 9, and the expression of transient receptor potential vanilloid type 1 (TRPV1), ankyrin type 1 (TRPA1), and melastatin type 8 (TRPM8) receptors in the ipsilateral L5 dorsal root ganglion was analyzed. The perineural administration of BV to the spinal nerves attenuated the development of mechanical, thermal, and cold allodynia, and the BV pretreatment reduced the expression of TRPV1, TRPA1, TRPM8 and c - Fos in the ipsilateral dorsal root ganglion. The current study demonstrates that the perineural pretreatment with diluted bee venom before the induction of spinal nerve ligation significantly suppresses the development of neuropathic pain. Furthermore, this bee venom induced suppression was strongly related with the involvement of transient receptor potential family members.

  18. A variational synthesis nodal discrete ordinates method

    International Nuclear Information System (INIS)

    Favorite, J.A.; Stacey, W.M.

    1999-01-01

    A self-consistent nodal approximation method for computing discrete ordinates neutron flux distributions has been developed from a variational functional for neutron transport theory. The advantage of the new nodal method formulation is that it is self-consistent in its definition of the homogenized nodal parameters, the construction of the global nodal equations, and the reconstruction of the detailed flux distribution. The efficacy of the method is demonstrated by two-dimensional test problems

  19. The ordinal Kolmogorov-Sinai entropy: A generalized approximation

    Science.gov (United States)

    Eyebe Fouda, J. S. Armand; Koepf, Wolfram; Jacquir, Sabir

    2017-05-01

    We introduce the multi-dimensional ordinal arrays complexity as a generalized approximation of the ordinal Komogorov-Sinai entropy. The ordinal arrays entropy (OAE) is defined as the Shannon entropy of a series of m-ordinal patterns encoded symbols, while the ordinal arrays complexity (OAC) is defined as the differential of the OAE with respect to m. We theoretically establish that the OAC provides a better estimate of the complexity measure for short length time series. Simulations were carried out using discrete maps, and confirm the efficiency of the OAC as complexity measure from a small data set even in a noisy environment.

  20. Regressão logística ordinal em estudos epidemiológicos Regresión logística ordinal en estudios epidemiológicos Ordinal logistic regression in epidemiological studies

    Directory of Open Access Journals (Sweden)

    Mery Natali Silva Abreu

    2009-02-01

    Full Text Available Os modelos de regressão logística ordinal vêm sendo aplicados com sucesso na análise de estudos epidemiológicos. Entretanto, a verificação da adequação de cada modelo tem recebido atenção limitada. O artigo apresenta uma breve análise dos principais modelos de regressão logística ordinal e as estratégias para ajuste s, as técnicas de verificação de qualidade do ajuste, bem como os comandos para execução nos softwares R e Stata. A metodologia é ilustrada com aplicação dos dados do Second National Health and Nutrition Examination Survey (NHANES II, o conhecido levantamento de saúde e nutrição.Los modelos de regresión logística ordinal vienen aplicándose con éxito en el análisis de estudios epidemiológicos. Sin embargo, la verificación de la adecuación de cada modelo ha recibido atención limitada. El artículo presenta un breve análisis de los principales modelos de regresión logística ordinal y las estrategias para ajustes, las técnicas de verificación de calidad de ajuste, así como los comandos para ejecución en los softwares R y Stata. La metodología es ilustrada con la aplicación de los datos del Second Nacional Health and Nutrition Examination Survey (NHANES II, el conocido análisis de salud y nutrición.Ordinal logistic regression models have been developed for analysis of epidemiological studies. However, the adequacy of such models for adjustment has so far received little attention. In this article, we reviewed the most important ordinal regression models and common approaches used to verify goodness-of-fit, using R or Stata programs. We performed formal and graphical analyses to compare ordinal models using data sets on health conditions from the National Health and Nutrition Examination Survey (NHANES II.

  1. The nodal discrete-ordinate transport calculation of anisotropy scattering problem in three-dimensional cartesian geometry

    International Nuclear Information System (INIS)

    Wu Hongchun; Xie Zhongsheng; Zhu Xuehua

    1994-01-01

    The nodal discrete-ordinate transport calculating model of anisotropy scattering problem in three-dimensional cartesian geometry is given. The computing code NOTRAN/3D has been encoded and the satisfied conclusion is gained

  2. UK Natural Analogue Co-Ordinating Group: first annual progress report

    International Nuclear Information System (INIS)

    Hooker, P.J.; Chapman, N.A.

    1987-11-01

    The British Geological Survey is reponsible for co-ordinating the Department of the Environment's programme of natural analogue studies of radionuclide migration, a research programme that involved both UK and overseas sites. Co-ordination is achieved through the UK Natural Analogue Co-ordinating Group (NACG) which was established in October 1986. It has met three times to date and its function is to ensure that the different research projects have an integrated purpose aimed at improving and applying our understanding of natural geochemical processes in a way that will increase our confidence in long-term modelling predictions. Improved modelling prediction of radionuclide transport in the geosphere will directly benefit the performance and safety assessments of proposed radioactive waste repositories. (author)

  3. Kinetic Modelling and Experimental Studies for the Effects of Fe2+ Ions on Xylan Hydrolysis with Dilute-Acid Pretreatment and Subsequent Enzymatic Hydrolysis

    Directory of Open Access Journals (Sweden)

    Hui Wei

    2018-01-01

    Full Text Available High-temperature (150–170 °C pretreatment of lignocellulosic biomass with mineral acids is well established for xylan breakdown. Fe2+ is known to be a cocatalyst of this process although kinetics of its action remains unknown. The present work addresses the effect of ferrous ion concentration on sugar yield and degradation product formation from corn stover for the entire two-step treatment, including the subsequent enzymatic cellulose hydrolysis. The feedstock was impregnated with 0.5% acid and 0.75 mM iron cocatalyst, which was found to be optimal in preliminary experiments. The detailed kinetic data of acid pretreatment, with and without iron, was satisfactorily modelled with a four-step linear sequence of first-order irreversible reactions accounting for the formation of xylooligomers, xylose and furfural as intermediates to provide the values of Arrhenius activation energy. Based on this kinetic modelling, Fe2+ turned out to accelerate all four reactions, with a significant alteration of the last two steps, that is, xylose degradation. Consistent with this model, the greatest xylan conversion occurred at the highest severity tested under 170 °C/30 min with 0.75 mM Fe2+, with a total of 8% xylan remaining in the pretreated solids, whereas the operational conditions leading to the highest xylose monomer yield, 63%, were milder, 150 °C with 0.75 mM Fe2+ for 20 min. Furthermore, the subsequent enzymatic hydrolysis with the prior addition of 0.75 mM of iron(II increased the glucose production to 56.3% from 46.3% in the control (iron-free acid. The detailed analysis indicated that conducting the process at lower temperatures yet long residence times benefits the yield of sugars. The above kinetic modelling results of Fe2+ accelerating all four reactions are in line with our previous mechanistic research showing that the pretreatment likely targets multiple chemistries in plant cell wall polymer networks, including those represented by the C

  4. Variational Gaussian Process Auto-Encoder for Ordinal Prediction of Facial Action Units

    NARCIS (Netherlands)

    Eleftheriadis, Stefanos; Rudovic, Ognjen; Deisenroth, Marc Peter; Pantic, Maja; Lai, Shang-Hong; Lepetit, Vincent; Nishino, Ko; Sato, Yoichi

    2016-01-01

    We address the task of simultaneous feature fusion and modeling of discrete ordinal outputs. We propose a novel Gaussian process (GP) auto-encoder modeling approach. In particular, we introduce GP encoders to project multiple observed features onto a latent space, while GP decoders are responsible

  5. Detecting DIF in Polytomous Items Using MACS, IRT and Ordinal Logistic Regression

    Science.gov (United States)

    Elosua, Paula; Wells, Craig

    2013-01-01

    The purpose of the present study was to compare the Type I error rate and power of two model-based procedures, the mean and covariance structure model (MACS) and the item response theory (IRT), and an observed-score based procedure, ordinal logistic regression, for detecting differential item functioning (DIF) in polytomous items. A simulation…

  6. Model description and evaluation of model performance, scenario S. Multiple pathways assessment of the IAEA/CEC co-ordinated research programme on validation of environmental model predictions (VAMP)

    Energy Technology Data Exchange (ETDEWEB)

    Suolanen, V. [VTT Energy, Espoo (Finland). Nuclear Energy

    1996-12-01

    A modelling approach was used to predict doses from a large area deposition of {sup 137}Cs over southern and central Finland. The assumed deposition profile and quantity were both similar to those resulting from the Chernobyl accident. In the study, doses via terrestrial and aquatic environments have been analyzed. Additionally, the intermediate results of the study, such as concentrations in various foodstuffs and the resulting body burdents, were presented. The contributions of ingestion, inhalation and external doses to the total dose were estimated in the study. The considered deposition scenario formed a modelling exercise in the IAEA coordinated research programme on Validation of Environmental Model Predictions, the VAMP project. (21 refs.).

  7. Model description and evaluation of model performance, scenario S. Multiple pathways assessment of the IAEA/CEC co-ordinated research programme on validation of environmental model predictions (VAMP)

    International Nuclear Information System (INIS)

    Suolanen, V.

    1996-12-01

    A modelling approach was used to predict doses from a large area deposition of 137 Cs over southern and central Finland. The assumed deposition profile and quantity were both similar to those resulting from the Chernobyl accident. In the study, doses via terrestrial and aquatic environments have been analyzed. Additionally, the intermediate results of the study, such as concentrations in various foodstuffs and the resulting body burdents, were presented. The contributions of ingestion, inhalation and external doses to the total dose were estimated in the study. The considered deposition scenario formed a modelling exercise in the IAEA coordinated research programme on Validation of Environmental Model Predictions, the VAMP project. (21 refs.)

  8. Continuous anaerobic digestion of swine manure: ADM1-based modelling and effect of addition of swine manure fibers pretreated with aqueous ammonia soaking

    International Nuclear Information System (INIS)

    Jurado, E.; Antonopoulou, G.; Lyberatos, G.; Gavala, H.N.; Skiadas, I.V.

    2016-01-01

    Highlights: • Aqueous ammonia soaking (AAS) effect on methane yield: verification in continuously fed digesters. • AAS resulted in 98% increase of the methane yield of swine manure fibers in continuously fed digesters. • ADM1 was successfully adapted to simulating anaerobic digestion of swine manure. • Modification of hydrolysis kinetics was necessary for an adequate simulation of the digestion of AAS-treated fibers. - Abstract: Anaerobic digestion of manure fibers presents challenges due to their low biodegradability. Aqueous ammonia soaking (AAS) has been tested as a simple method to disrupt the lignocellulose and increase the methane yield of manure fibers. In the present study, mesophilic anaerobic digestion of AAS pretreated manure fibers was performed in CSTR-type digesters, fed with swine manure and/or a mixture of swine manure and AAS pretreated manure fibers (at a total solids based ratio of 0.52 manure per 0.48 fibers). Two different simulations were performed. In the first place, the Anaerobic Digestion Model 1 (ADM1) was fitted to a manure-fed, CSTR-type digester and validated by simulating the performance of a second reactor digesting manure. It was shown that disintegration and hydrolysis of the solid matter of manure was such a slow process that the organic particulate matter did not significantly contribute to the methane production. In the second place, ADM1 was used to describe biogas production from the codigestion of manure and AAS pretreated manure fibers. The model predictions regarding biogas production and methane content were in good agreement with the experimental data. It was shown that, AAS treatment significantly increased the disintegration and hydrolysis rate of the carbohydrate compounds of the fibers. The effect of the addition of AAS treated fibers on the kinetics of the conversion of other key compounds such as volatile fatty acids was negligible.

  9. In vivo pretreatment of Eudrilus eugeniae powder attenuates β-adrenoceptor toxicity mediated by isoproterenol in rat model

    Directory of Open Access Journals (Sweden)

    Jaganathan Anitha

    2016-08-01

    Full Text Available The present study was designed to discover the potential cardioprotective function of earthworm powder (EWP extracted from Eudrilus eugeniae on isoproterenol (ISO-induced myocardial infarction in male Wistar rats. The rats were divided into four groups, with six rats in each group. Certain rats were pretreated with EWP (200 mg/kg bwt (Group III, and a myocardial infarction was then induced by subcutaneous injection of ISO (85 mg/kg bwt (Group II. Oral pretreatment of 200 mg/kg bwt of EWP for 28 days significantly (p > 0.05 improved the blood profile levels, including (a the lipid profile of total cholesterol (TC, free fatty acids (FFA, and triglycerides (TG; (b low-density lipoprotein (LDL, very low-density lipoprotein (VLDL, high-density lipoprotein (HDL, and protein; and (c A/G ratio, glucose and uric acid levels. The electrophoretic pattern of elevated lactose dehydrogenase (LDH levels was recovered by EWP treatment as evidenced by comparison with ISO-induced rats with cardiac damage. The above results indicate that EWP (200 mg/kg bwt provides a cardioprotective effect by attenuating the blood profile, lipid profile, biochemical levels, and LDH patterns in rats that experienced an ISO-induced myocardial infarction.

  10. Matrix albedo for discrete ordinates infinite-medium boundary condition

    International Nuclear Information System (INIS)

    Mathews, K.; Dishaw, J.

    2007-01-01

    Discrete ordinates problems with an infinite exterior medium (reflector) can be more efficiently computed by eliminating grid cells in the exterior medium and applying a matrix albedo boundary condition. The albedo matrix is a discretized bidirectional reflection distribution function (BRDF) that accounts for the angular quadrature set, spatial quadrature method, and spatial grid that would have been used to model a portion of the exterior medium. The method is exact in slab geometry, and could be used as an approximation in multiple dimensions or curvilinear coordinates. We present an adequate method for computing albedo matrices and demonstrate their use in verifying a discrete ordinates code in slab geometry by comparison with Ganapol's infinite medium semi-analytic TIEL benchmark. With sufficient resolution in the spatial and angular grids and iteration tolerance to yield solutions converged to 6 digits, the conventional (scalar) albedo boundary condition yielded 2-digit accuracy at the boundary, but the matrix albedo solution reproduced the benchmark scalar flux at the boundary to all 6 digits. (authors)

  11. Methods for pretreating biomass

    Science.gov (United States)

    Balan, Venkatesh; Dale, Bruce E; Chundawat, Shishir; Sousa, Leonardo

    2017-05-09

    A method for pretreating biomass is provided, which includes, in a reactor, allowing gaseous ammonia to condense on the biomass and react with water present in the biomass to produce pretreated biomass, wherein reactivity of polysaccharides in the biomass is increased during subsequent biological conversion as compared to the reactivity of polysaccharides in biomass which has not been pretreated. A method for pretreating biomass with a liquid ammonia and recovering the liquid ammonia is also provided. Related systems which include a biochemical or biofuel production facility are also disclosed.

  12. Differential item functioning analysis with ordinal logistic regression techniques. DIFdetect and difwithpar.

    Science.gov (United States)

    Crane, Paul K; Gibbons, Laura E; Jolley, Lance; van Belle, Gerald

    2006-11-01

    We present an ordinal logistic regression model for identification of items with differential item functioning (DIF) and apply this model to a Mini-Mental State Examination (MMSE) dataset. We employ item response theory ability estimation in our models. Three nested ordinal logistic regression models are applied to each item. Model testing begins with examination of the statistical significance of the interaction term between ability and the group indicator, consistent with nonuniform DIF. Then we turn our attention to the coefficient of the ability term in models with and without the group term. If including the group term has a marked effect on that coefficient, we declare that it has uniform DIF. We examined DIF related to language of test administration in addition to self-reported race, Hispanic ethnicity, age, years of education, and sex. We used PARSCALE for IRT analyses and STATA for ordinal logistic regression approaches. We used an iterative technique for adjusting IRT ability estimates on the basis of DIF findings. Five items were found to have DIF related to language. These same items also had DIF related to other covariates. The ordinal logistic regression approach to DIF detection, when combined with IRT ability estimates, provides a reasonable alternative for DIF detection. There appear to be several items with significant DIF related to language of test administration in the MMSE. More attention needs to be paid to the specific criteria used to determine whether an item has DIF, not just the technique used to identify DIF.

  13. WE-AB-202-11: Radiobiological Modeling of Tumor Response During Radiotherapy Based On Pre-Treatment Dynamic PET Imaging Data

    International Nuclear Information System (INIS)

    Crispin-Ortuzar, M; Grkovski, M; Beattie, B; Lee, N; Riaz, N; Humm, J; Jeong, J; Fontanella, A; Deasy, J

    2016-01-01

    Purpose: To evaluate the ability of a multiscale radiobiological model of tumor response to predict mid-treatment hypoxia images, based on pretreatment imaging of perfusion and hypoxia with [18-F]FMISO dynamic PET and glucose metabolism with [18-F]FDG PET. Methods: A mechanistic tumor control probability (TCP) radiobiological model describing the interplay between tumor cell proliferation and hypoxia (Jeong et al., PMB 2013) was extended to account for intra-tumor nutrient heterogeneity, dynamic cell migration due to nutrient gradients, and stromal cells. This extended model was tested on 10 head and neck cancer patients treated with chemoradiotherapy, randomly drawn from a larger MSKCC protocol involving baseline and mid-therapy dynamic PET scans. For each voxel, initial fractions of proliferative and hypoxic tumor cells were obtained by finding an approximate solution to a system of linear equations relating cell fractions to voxel-level FDG uptake, perfusion (FMISO K 1 ) and hypoxia (FMISO k 3 ). The TCP model then predicted their evolution over time up until the mid treatment scan. Finally, the linear model was reapplied to predict each lesion’s median hypoxia level (k 3 [med,sim]) which in turn was compared to the FMISO k 3 [med] measured at mid-therapy. Results: The average k3[med] of the tumors in pre-treatment scans was 0.0035 min −1 , with an inter-tumor standard deviation of σ[pre]=0.0034 min −1 . The initial simulated k 3 [med,sim] of each tumor agreed with the corresponding measurements within 0.1σ[pre]. In 7 out of 10 lesions, the mid-treatment k 3 [med,sim] prediction agreed with the data within 0.3σ[pre]. The remaining cases corresponded to the most extreme relative changes in k 3 [med]. Conclusion: This work presents a method to personalize the prediction of a TCP model using pre-treatment kinetic imaging data, and validates the modeling of radiotherapy response by predicting changes in median hypoxia values during treatment. Variations

  14. WE-AB-202-11: Radiobiological Modeling of Tumor Response During Radiotherapy Based On Pre-Treatment Dynamic PET Imaging Data

    Energy Technology Data Exchange (ETDEWEB)

    Crispin-Ortuzar, M; Grkovski, M; Beattie, B; Lee, N; Riaz, N; Humm, J; Jeong, J; Fontanella, A; Deasy, J [Memorial Sloan Kettering Cancer Center, New York, NY (United States)

    2016-06-15

    Purpose: To evaluate the ability of a multiscale radiobiological model of tumor response to predict mid-treatment hypoxia images, based on pretreatment imaging of perfusion and hypoxia with [18-F]FMISO dynamic PET and glucose metabolism with [18-F]FDG PET. Methods: A mechanistic tumor control probability (TCP) radiobiological model describing the interplay between tumor cell proliferation and hypoxia (Jeong et al., PMB 2013) was extended to account for intra-tumor nutrient heterogeneity, dynamic cell migration due to nutrient gradients, and stromal cells. This extended model was tested on 10 head and neck cancer patients treated with chemoradiotherapy, randomly drawn from a larger MSKCC protocol involving baseline and mid-therapy dynamic PET scans. For each voxel, initial fractions of proliferative and hypoxic tumor cells were obtained by finding an approximate solution to a system of linear equations relating cell fractions to voxel-level FDG uptake, perfusion (FMISO K{sub 1}) and hypoxia (FMISO k{sub 3}). The TCP model then predicted their evolution over time up until the mid treatment scan. Finally, the linear model was reapplied to predict each lesion’s median hypoxia level (k{sub 3}[med,sim]) which in turn was compared to the FMISO k{sub 3}[med] measured at mid-therapy. Results: The average k3[med] of the tumors in pre-treatment scans was 0.0035 min{sup −1}, with an inter-tumor standard deviation of σ[pre]=0.0034 min{sup −1}. The initial simulated k{sub 3}[med,sim] of each tumor agreed with the corresponding measurements within 0.1σ[pre]. In 7 out of 10 lesions, the mid-treatment k{sub 3}[med,sim] prediction agreed with the data within 0.3σ[pre]. The remaining cases corresponded to the most extreme relative changes in k{sub 3}[med]. Conclusion: This work presents a method to personalize the prediction of a TCP model using pre-treatment kinetic imaging data, and validates the modeling of radiotherapy response by predicting changes in median hypoxia

  15. Analysis of the morphology of oral structures from 3-D co-ordinate data.

    Science.gov (United States)

    Jovanovski, V; Lynch, E

    2000-01-01

    A non-intrusive method is described which can be used to determine the forms of oral structures. It is based on the digitising of standard replicas with a co-ordinate-measuring machine. Supporting software permits a mathematical model of the surface to be reconstructed and visualised from captured three-dimensional co-ordinates. A series of surface data sets can be superposed into a common reference frame without the use of extrinsic markers, allowing changes in the shapes of oral structures to be quantified accurately over an extended period of time. The system has found numerous applications.

  16. Hydrogen transport in a toroidal plasma using multigroup discrete-ordinates methodology

    International Nuclear Information System (INIS)

    Wienke, B.R.; Miller, W.F. Jr.; Seed, T.J.

    1979-01-01

    Neutral hydrogen transport in a fully ionized two-dimensional tokamak plasma was examined using discrete ordinates and contrasted with earlier analyses. In particular, curvature effects induced by toroidal geometries and ray effects caused by possible source localization were investigated. From an overview of the multigroup discrete-ordinates approximation, methodology in two-dimensional cylindrical geometry is detailed, mesh and plasma zoning procedures are sketched, and the piecewise polynomial solution algorithm on a triangular domain is obtained. Toroidal effects and comparisons as related to reaction rates and perticle spectra are examined for various model and source configurations

  17. The Pakistan atomic energy commission ordinance, 1965 ordinance no. XVII of 1965

    International Nuclear Information System (INIS)

    1983-01-01

    This act, entitled Pakistan Atomic Energy Commission ordinance 1965, allows amendments incorporated under PAEC (amendment) act 1974 upto August 1983. The amendments relates to regulations concerned with the composition and functions of the commission and some miscellaneous rules. (A.B.)

  18. An assessment of the effects of a cadmium discharge ordinance

    International Nuclear Information System (INIS)

    Moser, J.H.; Schultz, J.L.

    1982-01-01

    The problem facing the MMSD was high levels of cadmium in Milorganite fertilizer. The cause was determined to be discharges from industry, primarily electroplaters. The solution was the cooperative development of an ordinance to limit the discharge of cadmium. Because the dischargers acted responsibly to comply with the ordinance, the ordinance succeeded in achieving its objective of significantly reducing the cadmium loading to the municipal sewerage system and subsequently reducing the cadmium concentration in Milorganite fertilizer

  19. Ordinance on the transport of dangerous goods by road (SDR)

    International Nuclear Information System (INIS)

    1985-04-01

    This Ordinance regulates the transport of dangerous goods by road and replaces a similar Ordinance of 1972. The dangerous goods are listed in Annex A and the special provisions to be complied with for their transport are contained in Annex B. Radioactive materials, categorized as Class IVb, are included in the goods covered by the Ordinance. The Ordinance which entered into force on 1 May 1985 was amended on 9 April 1987 on a minor point and on 27 November 1989 so as to provide for special training for drivers of vehicles carrying such goods. This latter amendment entered into force on 1 January 1990. (NEA) [fr

  20. Pretreatment of microbial sludges

    Science.gov (United States)

    Rivard, Christopher J.; Nagle, Nicholas J.

    1995-01-01

    Methods are described for pretreating microbial sludges to break cells and disrupt organic matter. One method involves the use of sonication, and another method involves the use of shear forces. The pretreatment of sludge enhances bioconversion of the organic fraction. This allows for efficient dewatering of the sludge and reduces the cost for final disposal of the waste.

  1. Factors Linked to Identification with a Super-Ordinate Category in a ...

    African Journals Online (AJOL)

    Multiple regression analyses suggested that factors linked to identification with a super-ordinate category were related more to personal variables than to status differentiation and distribution of resources. These results are discussed with reference to the Common Ingroup Identity model (Gaertner et al, 1993), Breakwell's ...

  2. Modeling of radiant heat transfers in non-grey gases using the discrete ordinate method in association with a narrow bands statistical model; Modelisation des transferts radiatifs dans des gaz non gris par la methode des ordonnees discretes associee a un modele statistique a bandes etroites

    Energy Technology Data Exchange (ETDEWEB)

    Miranda, A.B. de; Delmas, A.; Sacadura, J.F. [Institut National des Sciences Appliquees (INSA), 69 - Villeurbanne (France)

    1996-12-31

    A formulation based on the use of the discrete ordinate method applied to the integral form of the radiant heat transfer equation is proposed for non-grey gases. The correlations between transmittances are neglected and no explicit wall reflexion is considered. The configuration analyzed consists in a flat layer of non-isothermal steam-nitrogen mixture. Cavity walls are grey with diffuse reflexion and emission. A narrow band statistical model is used to represent the radiative properties of the gas. The distribution of the radiative source term inside the cavity is calculated along two temperature profiles in a uniform steam concentration. Results obtained using this simplified approach are in good agreement with those found in the literature for the same temperature and concentration distributions. This preliminary study seems to indicate that the algorithm based on the integration of radiant heat transfer along the luminance path is less sensitive to de-correlation effects than formulations based on the differential form the the radiant heat transfer. Thus, a more systematic study of the influence of the neglecting of correlations on the integral approach is analyzed in this work. (J.S.) 16 refs.

  3. Carbonic Acid Pretreatment of Biomass

    Energy Technology Data Exchange (ETDEWEB)

    G. Peter van Walsum; Kemantha Jayawardhana; Damon Yourchisin; Robert McWilliams; Vanessa Castleberry

    2003-05-31

    acid compared to water alone. 6) Determine optimal conditions for carbonic acid pretreatment of aspen wood. Optimal severities appeared to be in the mid range tested. ASPEN-Plus modeling and economic analysis of the process indicate that the process could be cost competitive with sulfuric acid if the concentration of solids in the pretreatment is maintained very high (~50%). Lower solids concentrations result in larger reactors that become expensive to construct for high pressure applications.

  4. Effect of Shen-Fu Injection Pretreatment to Myocardial Metabolism During Untreated Ventricular Fibrillation in a Porcine Model

    Directory of Open Access Journals (Sweden)

    Wei Yuan

    2015-01-01

    Full Text Available Background: Shen-Fu injection (SFI can attenuate ischemia-reperfusion injury, protect cardiac function, and improve microcirculation during cardiopulmonary resuscitation. We hypothesized that SFI may also have an influence on myocardial metabolism during ventricular fibrillation (VF. In this study, we used SFI pretreatment prior to VF to discuss the changes of myocardial metabolism and catecholamine (CA levels during untreated VF, trying to provide new evidence to the protection of SFI to myocardium. Methods: Twenty-four pigs were divided into three groups: Saline group (SA group, SFI group, and SHAM operation group (SHAM group. Thirty minutes prior to the induction of VF, the SFI group received 0.24 mg/ml SFI through an intravenous injection; the SA group received an equal amount of sodium chloride solution. The interstitial fluid from the left ventricle (LV wall was collected through the microdialysis tubes during VF. Adenosine diphosphate (ADP, adenosine triphosphate (ATP, and Na + -K + -ATPase and Ca2 + -ATPase enzyme activities were measured after untreated VF. Peak-to-trough VF amplitude and median frequency were analyzed for each of these 5-s intervals. Results: The levels of glucose and glutamate were lower after VF in both the SA and SFI groups, compared with baseline, and the levels in the SFI group were higher than those in the SA group. Compared with baseline, the levels of lactate and the lactate/pyruvate ratio increased after VF in both SA and SFI groups, and the levels in the SFI group were lower than those in the SA group. In both the SA and SFI groups, the levels of dopamine, norepinephrine, and epinephrine increased significantly. There were no statistical differences between the two groups. The content of ATP, ADP, and phosphocreatine in the SFI group was higher than those in the SA group. The activity of LV Na + -K + -ATPase was significantly higher in the SFI group than in the SA group. Amplitude mean spectrum area (AMSA was

  5. Ordinal Welfare Comparisons with Multiple Discrete Indicators

    DEFF Research Database (Denmark)

    Arndt, Channing; Distante, Roberta; Hussain, M. Azhar

    We develop an ordinal method for making welfare comparisons between populations with multidimensional discrete well-being indicators observed at the micro level. The approach assumes that, for each well-being indicator, the levels can be ranked from worse to better; however, no assumptions are made...... about relative importance of any dimension nor about complementarity/substitutability relationships between dimensions. The method is based on the concept of multidimensional first order dominance. We introduce a rapid and reliable algorithm for empirically determining whether one population dominates...... another on the basis of available binary indicators by drawing upon linear programming theory. These approaches are applied to household survey data from Vietnam and Mozambique with a focus on child poverty comparisons over time and between regions....

  6. An SPSSR -Menu for Ordinal Factor Analysis

    Directory of Open Access Journals (Sweden)

    Mario Basto

    2012-01-01

    Full Text Available Exploratory factor analysis is a widely used statistical technique in the social sciences. It attempts to identify underlying factors that explain the pattern of correlations within a set of observed variables. A statistical software package is needed to perform the calculations. However, there are some limitations with popular statistical software packages, like SPSS. The R programming language is a free software package for statistical and graphical computing. It offers many packages written by contributors from all over the world and programming resources that allow it to overcome the dialog limitations of SPSS. This paper offers an SPSS dialog written in theR programming language with the help of some packages, so that researchers with little or no knowledge in programming, or those who are accustomed to making their calculations based on statistical dialogs, have more options when applying factor analysis to their data and hence can adopt a better approach when dealing with ordinal, Likert-type data.

  7. An ordinal classification approach for CTG categorization.

    Science.gov (United States)

    Georgoulas, George; Karvelis, Petros; Gavrilis, Dimitris; Stylios, Chrysostomos D; Nikolakopoulos, George

    2017-07-01

    Evaluation of cardiotocogram (CTG) is a standard approach employed during pregnancy and delivery. But, its interpretation requires high level expertise to decide whether the recording is Normal, Suspicious or Pathological. Therefore, a number of attempts have been carried out over the past three decades for development automated sophisticated systems. These systems are usually (multiclass) classification systems that assign a category to the respective CTG. However most of these systems usually do not take into consideration the natural ordering of the categories associated with CTG recordings. In this work, an algorithm that explicitly takes into consideration the ordering of CTG categories, based on binary decomposition method, is investigated. Achieved results, using as a base classifier the C4.5 decision tree classifier, prove that the ordinal classification approach is marginally better than the traditional multiclass classification approach, which utilizes the standard C4.5 algorithm for several performance criteria.

  8. Using GIS to check co-ordinates of genebank accessions

    NARCIS (Netherlands)

    Hijmans, R.J.; Schreuder, M.; Cruz, de la J.; Guarino, L.

    1999-01-01

    The geographic co-ordinates of the locations where germplasm accessions have been collected are usually documented in genebank databases. However, the co-ordinate data are often incomplete and may contain errors. This paper describes procedures to check for errors, to determine the cause of these

  9. First ordinance amending the Ordinance on Rail Transport of Dangerous Goods (1. Amendment Ordinance Rail Transport of Dangerous Goods). As of June 22, 1983

    International Nuclear Information System (INIS)

    1983-01-01

    This Amendment which came into force on September 1, 1983 brings about modifications of many items of the original Ordinance on Rail Transport of Dangerous Goods and its supplement, as of August 29, 1979. (HSCH) [de

  10. 78 FR 49283 - Chicken Ranch Rancheria-Chicken Ranch Liquor Licensing Ordinance, Ordinance No. 12-10-03

    Science.gov (United States)

    2013-08-13

    ...] Chicken Ranch Rancheria--Chicken Ranch Liquor Licensing Ordinance, Ordinance No. 12-10-03 AGENCY: Bureau of Indian Affairs, Interior. ACTION: Notice. SUMMARY: This notice publishes the Chicken Ranch Liquor... consumption of liquor within the Indian Country of the Chicken Ranch Rancheria. The land is trust land and...

  11. Modelling of radionuclide interception and loss processes in vegetation and of transfer in semi-natural ecosystems. Second report of the VAMP terrestrial working group. Part of the IAEA/CEC co-ordinated research programme on the validation of environmental model predictions (VAMP)

    International Nuclear Information System (INIS)

    1996-01-01

    Following the Chernobyl accident and on the recommendation of the International Nuclear Safety Advisory Group (INSAG) in its Summary Report on the Post-Accident Review Meeting on the Chernobyl Accident, the IAEA established a Co-ordinated Research Programme on ''The Validation of Models for the Transfer of Radionuclides in Terrestrial, Urban and Aquatic Environments and the Acquisition of Data for that Purpose''. The programme seeks to use the information on the environmental behaviour of radionuclides which became available as a result of the measurement programmes instituted in the countries of the former USSR and in many European countries after April 1986 for the purpose of testing the reliability of assessment models. Such models find application in assessing the radiological impact of all parts of the nuclear fuel cycle. They are used at the planning and design stage to predict the radiological impact of planned nuclear facilities, in assessing the possible consequences of accidents involving releases of radioactive material to the environment and in establishing criteria for the implementation of countermeasures. In the operational phase they are used together with the results of environmental monitoring to demonstrate compliance with regulatory requirements regarding release limitation. Refs, figs and tabs

  12. Validation of models using Chernobyl fallout data from southern Finland. Scenario S. Second report of the VAMP multiple pathways assessment working group. Part of the IAEA/CEC co-ordinated research programme on the validation of environmental model predictions (VAMP)

    International Nuclear Information System (INIS)

    1996-09-01

    Following the Chernobyl accident and on the recommendation of the International Nuclear Safety Advisory Group (INSAG) in its Summary Report on the Post-Accident Review Meeting on the Chernobyl Accident (Safety Series No. 75-INSAG-1, IAEA, Vienna, 1986), the IAEA established a Co-ordinated Research Programme on ''The Validation of Models for the Transfer of Radionuclides in Terrestrial, Urban and Aquatic Environments and the Acquisition of Data for that Purpose''. The programme used the information on the environmental behaviour of radionuclides which became available as a result of the measurement programmes instituted in countries of the former Soviet Union and in many European countries after April 1986 for the purpose of testing the reliability of assessment models. Such models find application in assessing the radiological impact of all parts of the nuclear fuel cycle. They are used in the planning and design stage to predict the radiological impact of nuclear facilities and in assessing the possible consequences of accidents involving releases of radioactive material to the environment and in establishing criteria for the implementation of countermeasures. In the operational phase, they are used together with the results of environmental monitoring to demonstrate compliance with regulatory requirements concerned with radiation dose limitation. Refs, figs, tabs

  13. Prediction of spectral acceleration response ordinates based on PGA attenuation

    Science.gov (United States)

    Graizer, V.; Kalkan, E.

    2009-01-01

    Developed herein is a new peak ground acceleration (PGA)-based predictive model for 5% damped pseudospectral acceleration (SA) ordinates of free-field horizontal component of ground motion from shallow-crustal earthquakes. The predictive model of ground motion spectral shape (i.e., normalized spectrum) is generated as a continuous function of few parameters. The proposed model eliminates the classical exhausted matrix of estimator coefficients, and provides significant ease in its implementation. It is structured on the Next Generation Attenuation (NGA) database with a number of additions from recent Californian events including 2003 San Simeon and 2004 Parkfield earthquakes. A unique feature of the model is its new functional form explicitly integrating PGA as a scaling factor. The spectral shape model is parameterized within an approximation function using moment magnitude, closest distance to the fault (fault distance) and VS30 (average shear-wave velocity in the upper 30 m) as independent variables. Mean values of its estimator coefficients were computed by fitting an approximation function to spectral shape of each record using robust nonlinear optimization. Proposed spectral shape model is independent of the PGA attenuation, allowing utilization of various PGA attenuation relations to estimate the response spectrum of earthquake recordings.

  14. Why Overlearned Sequences are Special: Distinct Neural Networks for Ordinal Sequences

    OpenAIRE

    Vani ePariyadath; Vani ePariyadath; Mark H Plitt; Sara J Churchill; David M Eagleman; David M Eagleman

    2012-01-01

    Several observations suggest that overlearned ordinal categories (e.g., letters, numbers, weekdays, months) are processed differently than non-ordinal categories in the brain. In synesthesia, for example, anomalous perceptual experiences are most often triggered by members of ordinal categories (Rich et al., 2005; Eagleman, 2009). In semantic dementia, the processing of ordinal stimuli appears to be preserved relative to non-ordinal ones (Cappelletti et al., 2001). Moreover, ordinal stimuli o...

  15. Resveratrol pretreatment enhanced homing of SDF-1α-preconditioned bone marrow-derived mesenchymal stem cells in a rat model of liver cirrhosis.

    Science.gov (United States)

    Hajinejad, Mehrdad; Pasbakhsh, Parichehr; Omidi, Ameneh; Mortezaee, Keywan; Nekoonam, Saied; Mahmoudi, Reza; Kashani, Iraj Ragerdi

    2018-03-01

    Stromal cell-derived factor-1α (SDF-1α) has been known to implicate in homing of MSCs, and resveratrol has been reported to have a positive influence on SDF-1 level in the site of injury. In this study, a combined strategy was applied to evaluate bone marrow-derived MSCs (BMSCs) homing to the rat model of liver cirrhosis induced by common bile duct ligation (CBDL): (1) pretreatment delivery of resveratrol into the cirrhotic liver, and (2) transplantation of ex vivo BMSC preconditioning with SDF-1α. BMSCs were preconditioned with 10 ng/µL SDF-1α for 1 h and then labeled with the CM-Dil. Cirrhosis was induced by CBDL. Animals received intraperitoneal injection of resveratrol for 7 days, started on day 28 of CBDL post-operative. On day 36 post-operative, 1 × 10 6 of SDF-1α-preconditioned BMSCs was injected via caudal vein. Animals were sacrificed at 72 h post-cell transplantation. Immunofluorescence and flow cytometry assessments showed that the BMSC+SDF+RV group had an increased rate of homing into the liver, but it had a decreased rate of homing into the lung and spleen, as compared with the other groups (P SDF+RV group showed high protein expression of SIRT1, but low protein expression of p53 in the liver (P SDF-1α-preconditioned BMSCs in vitro, and that AKTs and CXCL12 expressed in injured liver undergoing resveratrol injection. Our findings suggest that reseveratrol pretreatment prior to SDF-1α preconditioning could be a promising strategy for designing cell-based therapies for liver cirrhosis. © 2017 Wiley Periodicals, Inc.

  16. 'Reference Biospheres' for solid radioactive waste disposal. Report of BIOMASS Theme 1 of the BIOsphere Modelling and ASSessment (BIOMASS) Programme. Part of the IAEA Co-ordinated Research Project on Biosphere Modelling and Assessment (BIOMASS)

    International Nuclear Information System (INIS)

    2003-07-01

    The IAEA Programme on BIOsphere Modelling and ASSessment (BIOMASS) was launched in Vienna in October 1996. The programme was concerned with developing and improving capabilities to predict the transfer of radionuclides in the environment. The programme had three themes: Theme 1: Radioactive Waste Disposal. The objective was to develop the concept of a standard or reference biosphere for application to the assessment of the long-term safety of repositories for radioactive waste. Under the general heading of 'Reference Biospheres', six Task Groups were established: Task Group 1: Principles for the Definition of Critical and Other Exposure Groups. Task Group 2: Principles for the Application of Data to Assessment Models. Task Group 3: Consideration of Alternative Assessment Contexts. Task Group 4: Biosphere System Identification and Justification. Task Group 5: Biosphere System Descriptions. Task Group 6: Model Development. Theme 2: Environmental Releases. BIOMASS provided an international forum for activities aimed at increasing the confidence in methods and models for the assessment of radiation exposure related to environmental releases. Two Working Groups addressed issues concerned with the reconstruction of radiation doses received by people from past releases of radionuclides to the environment and the evaluation of the efficacy of remedial measures. Theme 3: Biosphere Processes. The aim of this Theme was to improve capabilities for modelling the transfer of radionuclides in particular parts of the biosphere identified as being of potential radiological significance and where there were gaps in modelling approaches. This topic was explored using a range of methods including reviews of the literature, model inter-comparison exercises and, where possible, model testing against independent sources of data. Three Working Groups were established to examine the modelling of: (1) long term tritium dispersion in the environment; (2) radionuclide uptake by fruits; and (3

  17. Pinatubo Emulation in Multiple Models (POEMs): co-ordinated experiments in the ISA-MIP model intercomparison activity component of the SPARC Stratospheric Sulphur and it's Role in Climate initiative (SSiRC)

    Science.gov (United States)

    Lee, Lindsay; Mann, Graham; Carslaw, Ken; Toohey, Matthew; Aquila, Valentina

    2016-04-01

    The World Climate Research Program's SPARC initiative has a new international activity "Stratospheric Sulphur and its Role in Climate" (SSiRC) to better understand changes in stratospheric aerosol and precursor gaseous sulphur species. One component of SSiRC involves an intercomparison "ISA-MIP" of composition-climate models that simulate the stratospheric aerosol layer interactively. Within PoEMS each modelling group will run a "perturbed physics ensemble" (PPE) of interactive stratospheric aerosol (ISA) simulations of the Pinatubo eruption, varying several uncertain parameters associated with the eruption's SO2 emissions and model processes. A powerful new technique to quantify and attribute sources of uncertainty in complex global models is described by Lee et al. (2011, ACP). The analysis uses Gaussian emulation to derive a probability density function (pdf) of predicted quantities, essentially interpolating the PPE results in multi-dimensional parameter space. Once trained on the ensemble, a Monte Carlo simulation with the fast Gaussian emulator enabling a full variance-based sensitivity analysis. The approach has already been used effectively by Carslaw et al., (2013, Nature) to quantify the uncertainty in the cloud albedo effect forcing from a 3D global aerosol-microphysics model allowing to compare the sensitivy of different predicted quantities to uncertainties in natural and anthropogenic emissions types, and structural parameters in the models. Within ISA-MIP, each group will carry out a PPE of runs, with the subsequent analysis with the emulator assessing the uncertainty in the volcanic forcings predicted by each model. In this poster presentation we will give an outline of the "PoEMS" analysis, describing the uncertain parameters to be varied and the relevance to further understanding differences identified in previous international stratospheric aerosol assessments.

  18. Ordinance on the Finnish Centre of Radiation and Nuclear Safety

    International Nuclear Information System (INIS)

    1990-01-01

    This Ordinance was adopted in implementation of the 1983 Act setting up the Finnish Centre for Radiation and Nuclear Safety and the 1987 Nuclear Energy Act and entered into force on 1 November 1990. The Ordinance specifies the tasks of the Centre, as provided under both Acts, and gives it several supplementary responsibilities. In addition to its overall competence in respect of radiation safety, the Centre will carry out research into and supervise the health effects of radiation and maintain a laboratory for national measurements in that field. The Ordinance also sets out the Centre's organisation chart and the staff duties [fr

  19. Open Method of Co-Ordination for Demoi-Cracy?

    DEFF Research Database (Denmark)

    Borrás, Susana; Radaelli, Claudio

    2014-01-01

    Under which conditions does the open method of co-ordination match the standards for demoi-cracy? To answer this question, we need some explicit standards about demoi-cracy. In fact, open co-ordination serves three different but interrelated purposes in European Union policy: to facilitate...... convergence; to support learning processes; and to encourage exploration of policy innovation. By intersecting standards and purposes, we find open co-ordination is neither inherently ‘good’ nor ‘bad’ for demoi-cracy, as it depends on how it has been put into practice. Therefore, we qualify the answer...

  20. Women's Ordination in Denmark: The Humanization of the Ordained Ministry

    DEFF Research Database (Denmark)

    Pedersen, Else Marie Wiberg

    2009-01-01

    This article focuses on the tensions, within which the drama about the admittance of women to the ordination to ministry in the Danish folkchurch was played out: church - state; church - people; Catholic - Lutheran; sacred - secular; hierarchical - democratic; feminine - human. Until the ordination...... of women was legislatively made possible on June 4 1947, the drama was played out within a church-state-complex, and some of the players tried to discern between the ministry, to which women i special functions could be admitted (for example pastors in a women's prison), and the ordination, which...

  1. Amendments to ordinances in Radiation Protection Law; Novellierung der strahlenschutzrechtlichen Verordnungen

    Energy Technology Data Exchange (ETDEWEB)

    Heller, W.

    2007-05-15

    The last major reform of the German Radiation Protection Ordinance took place on July 26, 2001. The 'First Ordinance Amending Ordinances in Radiation Protection Law' now proposed is to cover primarily the necessary changes and supplements resulting from experience in the execution of the ordinances. They mainly relate to these issues: (1) the scope of application of the Radiation Protection Ordinance and of the x-ray Ordinance in medical research (2) the scope of application of the Radiation Protection Ordinance and the -ray Ordinance in unjustified types of activities (3) electronic communication ('e-government') (4) changes in the provisions about permits and announcements in the Radiation Protection Ordinance (5) new clearance levels in the Radiation Protection Ordinance (6) cross-border transports of 'NORM' materials (7) other changes in the scope of application of the Radiation Protection Ordinance (8) other changes in the x-ray area. (orig.)

  2. Cost-effectiveness of public-health policy options in the presence of pretreatment NNRTI drug resistance in sub-Saharan Africa: a modelling study.

    Science.gov (United States)

    Phillips, Andrew N; Cambiano, Valentina; Nakagawa, Fumiyo; Revill, Paul; Jordan, Michael R; Hallett, Timothy B; Doherty, Meg; De Luca, Andrea; Lundgren, Jens D; Mhangara, Mutsa; Apollo, Tsitsi; Mellors, John; Nichols, Brooke; Parikh, Urvi; Pillay, Deenan; Rinke de Wit, Tobias; Sigaloff, Kim; Havlir, Diane; Kuritzkes, Daniel R; Pozniak, Anton; van de Vijver, David; Vitoria, Marco; Wainberg, Mark A; Raizes, Elliot; Bertagnolio, Silvia

    2018-03-01

    There is concern over increasing prevalence of non-nucleoside reverse-transcriptase inhibitor (NNRTI) resistance in people initiating antiretroviral therapy (ART) in low-income and middle-income countries. We assessed the effectiveness and cost-effectiveness of alternative public health responses in countries in sub-Saharan Africa where the prevalence of pretreatment drug resistance to NNRTIs is high. The HIV Synthesis Model is an individual-based simulation model of sexual HIV transmission, progression, and the effect of ART in adults, which is based on extensive published data sources and considers specific drugs and resistance mutations. We used this model to generate multiple setting scenarios mimicking those in sub-Saharan Africa and considered the prevalence of pretreatment NNRTI drug resistance in 2017. We then compared effectiveness and cost-effectiveness of alternative policy options. We took a 20 year time horizon, used a cost effectiveness threshold of US$500 per DALY averted, and discounted DALYs and costs at 3% per year. A transition to use of a dolutegravir as a first-line regimen in all new ART initiators is the option predicted to produce the most health benefits, resulting in a reduction of about 1 death per year per 100 people on ART over the next 20 years in a situation in which more than 10% of ART initiators have NNRTI resistance. The negative effect on population health of postponing the transition to dolutegravir increases substantially with higher prevalence of HIV drug resistance to NNRTI in ART initiators. Because of the reduced risk of resistance acquisition with dolutegravir-based regimens and reduced use of expensive second-line boosted protease inhibitor regimens, this policy option is also predicted to lead to a reduction of overall programme cost. A future transition from first-line regimens containing efavirenz to regimens containing dolutegravir formulations in adult ART initiators is predicted to be effective and cost-effective in

  3. Physicochemical characterization, modelling and optimization of ultrasono-assisted acid pretreatment of two Pennisetum sp. using Taguchi and artificial neural networking for enhanced delignification.

    Science.gov (United States)

    Mohapatra, Sonali; Dandapat, Snigdha Jyotsna; Thatoi, Hrudayanath

    2017-02-01

    Acid as well as ultrasono-assisted acid pretreatment of lignocellulosic biomass of two Pennisetum sp.; Denanath grass (DG) and Hybrid Napier grass (HNG) have been investigated for enhanced delignification and maximum exposure of cellulose for production of bioethanol. Screening of pretreatment with different acids such as H 2 SO 4 , HCl, H 3 PO 4 and H 2 NO 3 were optimized for different temperature, soaking time and acid concentrations using Taguchi orthogonal array and the data obtained were statistically validated using artificial neural networking. HCl was found to be the most effective acid for pretreatment of both the Pennisetum sp. The optimized conditions of HCl pretreatment were acid concentration of 1% and 1.5%, soaking time 130 and 50 min and temperature 121 °C and 110 °C which yielded maximum delignification of 33.0% and 33.8% for DG and HNG respectively. Further ultrosono-assisted HCl pretreatment with a power supply of 100 W, temperature of 353 K, and duty cycle of 70% has resulted in significantly higher delignification of 80.4% and 82.1% for both DG and HNG respectively than that of acid pretreatment. Investigation using SEM, FTIR and autofloresence microscopy for both acid and ultrasono-assisted acid pretreatment lignocellulosic biomass revealed conformational changes of pretreated lignocellulosic biomass with decreased lignin content and increased exposure of cellulose, with greater effectiveness in case of ultrasono assisted acid pretreatment condition. Copyright © 2016. Published by Elsevier Ltd.

  4. GREET Pretreatment Module

    Energy Technology Data Exchange (ETDEWEB)

    Adom, Felix K. [Argonne National Lab. (ANL), Argonne, IL (United States). Energy Systems Division; Dunn, Jennifer B. [Argonne National Lab. (ANL), Argonne, IL (United States). Energy Systems Division; Han, Jeongwoo [Argonne National Lab. (ANL), Argonne, IL (United States). Energy Systems Division

    2014-09-01

    A wide range of biofuels and biochemicals can be produced from cellulosic biomass via different pretreatment technologies that yield sugars. Process simulations of dilute acid and ammonia fiber expansion pretreatment processes and subsequent hydrolysis were developed in Aspen Plus for four lignocellulosic feedstocks (corn stover, miscanthus, switchgrass, and poplar). This processing yields sugars that can be subsequently converted to biofuels or biochemical. Material and energy consumption data from Aspen Plus were then compiled in a new Greenhouses Gases, Regulated Emissions, and Energy Use in Transportation (GREETTM) pretreatment module. The module estimates the cradle-to-gate fossil energy consumption (FEC) and greenhouse gas (GHG) emissions associated with producing fermentable sugars. This report documents the data and methodology used to develop this module and the cradle-to-gate FEC and GHG emissions that result from producing fermentable sugars.

  5. The Utility of Ordinal Scales Inspired by Piaget's Observations

    Science.gov (United States)

    Hunt, J. McVicker

    1976-01-01

    Seven sequential ordinal scales of sensorimotor development are briefly described. These scales permit modification in the strategy for assessing infant development, investigating its structure and investigating infant-environment interaction. (GO)

  6. Improvements of the Vis-NIRS Model in the Prediction of Soil Organic Matter Content Using Spectral Pretreatments, Sample Selection, and Wavelength Optimization

    Science.gov (United States)

    Lin, Z. D.; Wang, Y. B.; Wang, R. J.; Wang, L. S.; Lu, C. P.; Zhang, Z. Y.; Song, L. T.; Liu, Y.

    2017-07-01

    A total of 130 topsoil samples collected from Guoyang County, Anhui Province, China, were used to establish a Vis-NIR model for the prediction of organic matter content (OMC) in lime concretion black soils. Different spectral pretreatments were applied for minimizing the irrelevant and useless information of the spectra and increasing the spectra correlation with the measured values. Subsequently, the Kennard-Stone (KS) method and sample set partitioning based on joint x-y distances (SPXY) were used to select the training set. Successive projection algorithm (SPA) and genetic algorithm (GA) were then applied for wavelength optimization. Finally, the principal component regression (PCR) model was constructed, in which the optimal number of principal components was determined using the leave-one-out cross validation technique. The results show that the combination of the Savitzky-Golay (SG) filter for smoothing and multiplicative scatter correction (MSC) can eliminate the effect of noise and baseline drift; the SPXY method is preferable to KS in the sample selection; both the SPA and the GA can significantly reduce the number of wavelength variables and favorably increase the accuracy, especially GA, which greatly improved the prediction accuracy of soil OMC with Rcc, RMSEP, and RPD up to 0.9316, 0.2142, and 2.3195, respectively.

  7. SPANDOM - source projection analytic nodal discrete ordinates method

    International Nuclear Information System (INIS)

    Kim, Tae Hyeong; Cho, Nam Zin

    1994-01-01

    We describe a new discrete ordinates nodal method for the two-dimensional transport equation. We solve the discrete ordinates equation analytically after the source term is projected and represented in polynomials. The method is applied to two fast reactor benchmark problems and compared with the TWOHEX code. The results indicate that the present method accurately predicts not only multiplication factor but also flux distribution

  8. Microwave pretreatment of switchgrass for bioethanol production

    Science.gov (United States)

    Keshwani, Deepak Radhakrishin

    conditions, 82% glucose and 63% xylose yields were achieved for switchgrass, and 87% glucose and 59% xylose yields were achieved for coastal bermudagrass following enzymatic hydrolysis of the pretreated biomass. The optimum enzyme loadings were 15 FPU/g and 20 CBU/g for switchgrass and 10 FPU/g and 20 CBU/g for coastal bermudagrass. Dielectric properties for dilute sodium hydroxide solutions were measured and compared to solid loss, lignin reduction and reducing sugar levels in hydrolyzates. Results indicate that the dielectric loss tangent of alkali solutions is a potential indicator of the severity of microwave-based pretreatments. Modeling of pretreatment processes can be a valuable tool in process simulations of bioethanol production from lignocellulosic biomass. Chapter 4 discusses three different approaches that were used to model delignification and carbohydrate loss during microwave-based pretreatment of switchgrass: statistical linear regression modeling, kinetic modeling using a time-dependent rate coefficient, and a Mamdani-type fuzzy inference system. The dielectric loss tangent of the alkali reagent and pretreatment time were used as predictors in all models. The statistical linear regression model for delignification gave comparable root mean square error (RMSE) values for training and testing data and predictions were approximately within 1% of experimental values. The kinetic model for delignification and xylan loss gave comparable RMSE values for training and testing data sets and predictions were approximately within 2% of experimental values. The kinetic model for cellulose loss was not as effective and predictions were only within 5-7% of experimental values. The time-dependent rate coefficients of the kinetic models calculated from experimental data were consistent with the heterogeneity (or lack thereof) of individual biomass components. The Mamdani-type fuzzy inference system was shown to be an effective means to model pretreatment processes and gave

  9. Pre-treatment with N-acetylcysteine upregulates superoxide dismutase 2 and catalase genes in cadmium-induced oxidative stress in the chick omphalocele model.

    Science.gov (United States)

    Doi, Takashi; Puri, Prem; Bannigan, John; Thompson, Jennifer

    2011-02-01

    In the chick embryo, administration of the heavy metal Cadmium (Cd) induces omphalocele phenotype. Cd is a potent inhibitor of antioxidant enzymes and causes accumulation of reactive oxygen species (ROSs) such as hydrogen peroxide. Previous work with the Cd chick model has demonstrated that increased levels of MDA, as a marker for oxidative stress, 24 h post Cd treatment (24H) are identical in chick embryos exposed to Cd. Furthermore, of the several antioxidants assessed, only N-acetylcysteine (NAC) has been shown to reduce MDA levels to control values in the Cd-treated chick embryo. However, the molecular mechanisms by which NAC acts to maintain oxidative stress in the Cd-induced ventral body wall defect chick model remains to be unclear. We designed this study to investigate the hypothesis that gene expression levels of antioxidant enzymes are downregulated in malformed embryos exposed to Cd compared to controls and to determine the effect of pre-treatment with NAC on the expression levels of genes encoding antioxidant enzymes. After 60 h incubation, chick embryos were pre-treated with NAC and exposed to either chick saline or Cd. Chicks were then harvested at 24H and divided into five groups: control, Cd group without malformation [Cd(-)], Cd group with malformation [Cd(+)], NAC + Cd(-) and NAC + Cd(+). Real-time PCR was performed to evaluate the relative mRNA expression levels of antioxidant enzymes, including superoxide dismutase (SOD)-1, SOD2, catalase (CAT) and glutathione peroxidase (GPX)-4. Differences between five groups were tested by Tukey-Kramer post-hoc test following one-way ANOVA. Statistical significance was accepted at p < 0.05. Immunohistochemistry was also performed to evaluate protein expression. The mRNA expression levels of SOD2 and CAT were significantly decreased in Cd(+) as compared to controls, whereas there was no significant difference between controls and Cd(-) (p < 0.05 vs. controls). In addition, gene expression levels of

  10. Overstatement in happiness reporting with ordinal, bounded scale.

    Science.gov (United States)

    Tanaka, Saori C; Yamada, Katsunori; Kitada, Ryo; Tanaka, Satoshi; Sugawara, Sho K; Ohtake, Fumio; Sadato, Norihiro

    2016-02-18

    There are various methods by which people can express subjective evaluations quantitatively. For example, happiness can be measured on a scale from 1 to 10, and has been suggested as a measure of economic policy. However, there is resistance to these types of measurement from economists, who often regard welfare to be a cardinal, unbounded quantity. It is unclear whether there are differences between subjective evaluation reported on ordinal, bounded scales and on cardinal, unbounded scales. To answer this question, we developed functional magnetic resonance imaging experimental tasks for reporting happiness from monetary gain and the perception of visual stimulus. Subjects tended to report higher values when they used ordinal scales instead of cardinal scales. There were differences in neural activation between ordinal and cardinal reporting scales. The posterior parietal area showed greater activation when subjects used an ordinal scale instead of a cardinal scale. Importantly, the striatum exhibited greater activation when asked to report happiness on an ordinal scale than when asked to report on a cardinal scale. The finding that ordinal (bounded) scales are associated with higher reported happiness and greater activation in the reward system shows that overstatement bias in happiness data must be considered.

  11. Modelling the transfer of radionuclides to fruit. Report of the Fruits Working Group of BIOMASS Theme 3. Part of the IAEA Co-ordinated Research Project on Biosphere Modelling and Assessment (BIOMASS)

    International Nuclear Information System (INIS)

    2003-07-01

    This report contains a description of the activities carried out by the Fruits Working Group and presents the main results such as conceptual advances, quantitative data and models on the transfer of radionuclides to fruit in the context of the overall objective of BIOMASS Theme 3. The aim of the study was to improve understanding of the processes affecting the migration of radionuclides in the fruit system and to identify the uncertainties associated with modelling the transfer of radionuclides to fruit. The overall objective was to improve the accuracy of risk assessment that should translate to improved health safety for the population and associated cost savings. The significance of fruit, intended as that particular component of the human diet generally consumed as a dessert item, derives from its high economic value, the agricultural area devoted to its cultivation, and its consumption rates. These are important factors for some countries and groups of population. Fruits may become contaminated with radioactive material from nuclear facilities during routine operation, as a consequence of nuclear accidents, or due to migration through the biosphere of radionuclides from radioactive waste disposal facilities. Relevant radionuclides when considering transfer to fruit from atmospheric deposition were identified as 3 H, 14 C, 35 S, 36 Cl, 90 Sr, 129 I, 134 Cs and 137 Cs. The transfer of radionuclides to fruit is complex and involves many interactions between biotic and abiotic components. Edible fruit is borne by different plant species, such as herbaceous plants, shrubs and trees, that can grow under different climatic conditions and may be found in agricultural or natural ecosystems. A review of experimental, field and modelling information on the transfer of radionuclides to fruit was carried out at the inception of the activities of the Group, taking into account results from a Questionnaire circulated to radioecologists. Results on current experimental

  12. Co-ordinated voltage control of DFIG wind turbines in uninterrupted operation during grid faults

    DEFF Research Database (Denmark)

    Hansen, Anca Daniela; Michalke, G.; Sørensen, Poul Ejnar

    2007-01-01

    -side converter as long as it is not blocked by the protection system, otherwise the grid-side converter takes over the voltage control. Moreover, the article presents a DFIG wind farm model equipped with a grid fault protection system and the described co-ordinated voltage control. The whole DFIG wind farm model......Emphasis in this article is on the design of a co-ordinated voltage control strategy for doubly fed induction generator (DFIG) wind turbines that enhances their capability to provide grid support during grid faults. In contrast to its very good performance in normal operation, the DFIG wind turbine...... concept is quite sensitive to grid faults and requires special power converter protection. The fault ride-through and grid support capabilities of the DFIG address therefore primarily the design of DFIG wind turbine control with special focus on power converter protection and voltage control issues...

  13. Donor pretreatment with carbamylated erythropoietin in a brain death model reduces inflammation more effectively than erythropoietin while preserving renal function

    NARCIS (Netherlands)

    Nijboer, Willemijn N.; Ottens, Petra J.; van Dijk, Antony; van Goor, Harry; Ploeg, Rutger J.; Leuvenink, Henri G. D.

    Objective: We hypothesized that donor treatment of deceased brain dead donors would lead to a decrease in inflammatory responses seen in brain death and lead to a restoration of kidney function. Design: A standardized slow-induction rat brain death model followed by evaluation of kidney function in

  14. Study on the Algorithm for Train Operation Adjustment Based on Ordinal Optimization

    OpenAIRE

    Yong-jun Chen; Ji-an Yu; Lei-shan Zhou; Qing Tao

    2013-01-01

    It is a crucial and difficult problem in railway transportation dispatch mechanism to automatically compile train operation adjustment (TOA) plan with computer to ensure safe, fast, and punctual running of trains. Based on the proposed model of TOA under the conditions of railway network (RN), we take minimum travel time of train as objective function of optimization, and after fast preliminary evaluation calculation on it, we introduce the theory and method of ordinal optimization (OO) to so...

  15. Ordinance on measures for preparation of a radioactive waste repository (Ordinance on preparatory measures) of 24 October 1979

    International Nuclear Information System (INIS)

    1981-01-01

    This Ordinance contains details concerning the special procedure provided for under Section 10(2) of the Federal Order of 6th October 1978 concerning the Atomic Energy Act whereby the Federal Council must grant permission before preparations for the construction of radioactive waste repositories may be undertaken. The Ordinance defines the preparatory measures, which include maps and plans of the area, a geological report, etc. (NEA) [fr

  16. Advances in aluminum pretreatment

    Energy Technology Data Exchange (ETDEWEB)

    Sudour, Michel; Maintier, Philippe [PPG Industries France, 3 Z.A.E. Les Dix Muids, B.P. 89, F-59583 Marly (France); Simpson, Mark [PPG Industries Inc., 1200 Piedmont Troy, Michigan 48083 (United States); Quaglia, Paolo [PPG Industries Italia, Via Garavelli 21, I-15028 Quattordio (Italy)

    2004-07-01

    As automotive manufacturers continue to look for ways to reduce vehicle weight, aluminum is finding more utility as a body panel component. The substitution of cold-rolled steel and zinc-coated substrates with aluminum has led to new challenges in vehicle pretreatment. As a result, changes to traditional pretreatment chemistries and operating practices are necessary in order to produce an acceptable coating on aluminum body panels. These changes result in increased sludging and other undesirable characteristics. In addition to the chemistry changes, there are also process-related problems to consider. Many existing automotive pretreatment lines simply were not designed to handle aluminum and its increased demands on filtration and circulation equipment. To retrofit such a system is capital intensive and in addition to requiring a significant amount of downtime, may not be totally effective. Thus, the complexities of pre-treating aluminum body panels have actually had a negative effect on efforts to introduce more aluminum into new vehicle design programs. Recent research into ways of reducing the negative effects has led to a new understanding of the nature of zinc phosphate bath -aluminum interactions. Many of the issues associated with the pretreatment of aluminum have been identified and can be mitigated with only minor changes to the zinc phosphate bath chemistry. The use of low levels of soluble Fe ions, together with free fluoride, has been shown to dramatically improve the efficiency of a zinc phosphate system processing aluminum. Appearance of zinc phosphate coatings, coating weights and sludge are all benefited by this chemistry change. (authors)

  17. Pretreatment with the Free Radical Scavenger Edaravone Mitigates Kidney Glycogen Depletion and Neutrophil Infiltration after Leg Ischemia in a Rat Model: A Pilot Study.

    Science.gov (United States)

    Yamamura, Mitsuhiro; Miyamoto, Yuji; Mitsuno, Masataka; Tanaka, Hiroe; Ryomoto, Masaaki

    2017-12-25

    Objective : We have previously shown that pretreatment with the free radical scavenger edaravone (Radicut ® , Mitsubishi Tanabe Pharma Co., Japan) mitigated skeletal muscle damage due to ischemia reperfusion. In this study, we sought to validate its use in an experimental model of myonephropathic-metabolic syndrome (MNMS). Methods : Either edaravone (3.0 mg/kg; edaravone group; n=4) or saline (saline group; n=6) was intraperitoneally injected into male Lewis rats (508±31 g). Normal kidneys were harvested as control (n=3). MNMS was induced by bilaterally clamping the common femoral arteries for 5 h and declamping 5 h later. Kidney damage was evaluated by quantifying Periodic Acid Schiff (PAS)-positive area (glycogen storage) and esterase-positive cells (neutrophil infiltration). Results : The PAS-positive area in the saline group was significantly lower than that in the normal group (36.9±2.6 vs. 66.9±1.2%, Pglycogen depletion and neutrophil infiltration.

  18. Insulation co-ordination and the enlargement law for the GM counter tube

    Directory of Open Access Journals (Sweden)

    Dolićanin Edin Ć.

    2016-01-01

    Full Text Available In this paper we analyze application of contemporary methods of insulation co-ordination and the enlargement law in designing a GM counting tube. It has been shown that by applying insulation co-ordination methods the counting tube can be optimally dimensioned. The application of the enlargement law was demonstrated in generalizing the results of test obtained by the GM tube to those obtained by the counting tube with m-times greater dimensions. The investigations were conducted both theoretically and by experiment. Using theoretical analysis, we derived the expressions that may be applied if a performance function of a random variable breakdown voltage is known. The experiments were conducted on a GM counter model under well controlled laboratory conditions.

  19. Nonhazardous Urine Pretreatment Method

    Science.gov (United States)

    Akse, James R.; Holtsnider, John T.

    2012-01-01

    A method combines solid phase acidification with two non-toxic biocides to prevent ammonia volatilization and microbial proliferation. The safe, non-oxidizing biocide combination consists of a quaternary amine and a food preservative. This combination has exhibited excellent stabilization of both acidified and unacidified urine. During pretreatment tests, composite urine collected from donors was challenged with a microorganism known to proliferate in urine, and then was processed using the nonhazardous urine pre-treatment method. The challenge microorganisms included Escherichia coli, a common gram-negative bacteria; Enterococcus faecalis, a ureolytic gram-positive bacteria; Candida albicans, a yeast commonly found in urine; and Aspergillus niger, a problematic mold that resists urine pre-treatment. Urine processed in this manner remained microbially stable for over 57 days. Such effective urine stabilization was achieved using non-toxic, non-oxidizing biocides at higher pH (3.6 to 5.8) than previous methods in use or projected for use aboard the International Space Station (ISS). ISS urine pretreatment methods employ strong oxidants including ozone and hexavalent chromium (Cr(VI)), a carcinogenic material, under very acidic conditions (pH = 1.8 to 2.4). The method described here offers a much more benign chemical environment than previous pretreatment methods, and will lower equivalent system mass (ESM) by reducing containment volume and mass, system complexity, and crew time needed to handle pre-treatment chemicals. The biocides, being non-oxidizing, minimize the potential for chemical reactions with urine constituents to produce volatile, airborne contaminants such as cyanogen chloride. Additionally, the biocides are active under significantly less acidic conditions than those used in the current system, thereby reducing the degree of required acidification. A simple flow-through solid phase acidification (SPA) bed is employed to overcome the natural buffering

  20. Impact of pretreatment on colour and texture of watermelon rind

    Science.gov (United States)

    Athmaselvi, K.; Alagusundaram, K.; Kavitha, C.; Arumuganathan, T.

    2012-07-01

    The effect of osmotic dehydration pretreatment on water loss, solid gain, colour and textural change was investigated. Watermelon rind 1 x 1 cm size was immersed in sucrose solution of 40, 50 and 60° Brix after pretreatment with microwave and conventional boiling in water for 1, 3, and 5 min, respectively. Water loss and solid gain increased with the time of cooking and sugar concentration. Microwave pretreated samples showed higher water loss and solid gain. Increase in the time of cooking decreased the brightness of all the samples. Microwave pretreated samples showed higher `b' values than conventionally pretreated ones. There was no significant difference (P≤0.05) in texture profile analysis parameters except for hardness. Hardness decreased with increase in time of cooking and sugar concentration. Second order regression model was developed for water loss and solid gain of microwave and conventional pretreated watermelon rind.

  1. Neuroprotective effect of pretreatment with Lavandula officinalis ethanolic extract on blood-brain barrier permeability in a rat stroke model.

    Science.gov (United States)

    Rabiei, Zahra; Rafieian-Kopaei, Mahmoud

    2014-09-01

    To evaluate the protective effect of Lavandula officinalis (L. officinalis) extract against blood-brain barrier (BBB) permeability and its possible mechanisms in an experimental model of stroke. Focal cerebral ischemia was induced by the transient occlusion of the middle cerebral artery for 1 h in rats. Lavender extract (100, 200 mg/kg i.p.) was injected for 20 consecutive days. BBB permeability and oxidative stress biomarkers were evaluated using standard methods. The results of this study showed that L. officinalis ethanolic extract significantly reduced the BBB permeability in experimental groups when compared with ischemia group. The lavender extract significantly reduced malondialdehyde levels of plasma and brain tissue in intact group when compared with control group. L. officinalis extract reduced blood brain barrier permeability and alleviated neurological function in rats, and the mechanism may be related to augmentation in endogenous antioxidant defense and inhibition of oxidative stress in the rat brain. Copyright © 2014 Hainan Medical College. Published by Elsevier B.V. All rights reserved.

  2. Local zoning ordinances -- how they limit or restrict mining

    International Nuclear Information System (INIS)

    Ingram, H.

    1991-01-01

    Local regulation of mining by zoning has taken place for a long period of time. The delegation to local municipalities of land use planning, zoning and nuisance abatement authority which may affect mining by state governments has been consistently upheld by appellate courts as valid exercises of the police power. Recently, mine operators and mineral owners have been confronted by efforts of local municipalities, often initiated by anti-mining citizen's groups, to impose more stringent restrictions on mining activities within their borders. In some situations, existing ordinances are being enforced for the first time, in others, new ordinances have been adopted without much awareness or involvement by the public. Enforced to the letter, these ordinances can sterilize large blocks of mineable reserves open-quotes operatingclose quotes or performance standards in excess of SMCRA-based regulatory requirements. It is fair to say that investigation of the potential impacts of local zoning and other related ordinances is essential in the planning for the expansion of existing operations or for new operations. There may be new rules in the game. This paper identifies problem areas in typical open-quotes modernclose quotes ordinances and discusses legal and constitutional issues which may arise by their enforcement in coal producing regions

  3. Biomass shock pretreatment

    Science.gov (United States)

    Holtzapple, Mark T.; Madison, Maxine Jones; Ramirez, Rocio Sierra; Deimund, Mark A.; Falls, Matthew; Dunkelman, John J.

    2014-07-01

    Methods and apparatus for treating biomass that may include introducing a biomass to a chamber; exposing the biomass in the chamber to a shock event to produce a shocked biomass; and transferring the shocked biomass from the chamber. In some aspects, the method may include pretreating the biomass with a chemical before introducing the biomass to the chamber and/or after transferring shocked biomass from the chamber.

  4. An Ordination of the Vegetation of Ntshongweni, Natal*

    Directory of Open Access Journals (Sweden)

    J. W. Morris

    1969-11-01

    Full Text Available The physiography, soils, climate and dense woody vegetation are briefly described for Ntshongweni, a cone-shaped hill in Natal, South Africa (29° 51' S and 30° 43' E. A primary ordination of the woody plants, based on Bray & Curtis’s (1957 method, was carried out using 60 quadrats. Four stand noda were delimited and another four noda within a secondary ordination of a cluster of quadrats which could not be interpreted within the primary ordination. Edaphic and atmospheric moisture conditions and slope aspect were proposed as the main site factors correlated with species performance. Tables of density, local frequency and constancy for species occurring in each nodum were drawn up.

  5. Ordinance of 30 June 1976 on radiation protection

    International Nuclear Information System (INIS)

    1976-01-01

    This Ordinance on radiation protection lays down the licensing system for activities in Switzerland involving possible exposure to radiation, with the exception of nuclear installations, fuels and radioactive waste which, under the 1959 Atomic Energy Act, are subject to licensing. The Ordinance applies to the production, handling, use, storage, transport, disposal, import and export of radioactive substances and devices and articles containing them; and generally to any activity involving hazards caused by ionizing radiation. The Federal Public Health Service is the competent authority for granting licences. Provision is also made for the administrative conditions to be complied with for obtaining such licences as well as for technical measures required when engaged in work covered by the Ordinance. (NEA) [fr

  6. Projected discrete ordinates methods for numerical transport problems

    Energy Technology Data Exchange (ETDEWEB)

    Larsen, E.W.

    1985-01-01

    A class of Projected Discrete-Ordinates (PDO) methods is described for obtaining iterative solutions of discrete-ordinates problems with convergence rates comparable to those observed using Diffusion Synthetic Acceleration (DSA). The spatially discretized PDO solutions are generally not equal to the DSA solutions, but unlike DSA, which requires great care in the use of spatial discretizations to preserve stability, the PDO solutions remain stable and rapidly convergent with essentially arbitrary spatial discretizations. Numerical results are presented which illustrate the rapid convergence and the accuracy of solutions obtained using PDO methods with commonplace differencing methods.

  7. Quantitative characterisation of audio data by ordinal symbolic dynamics

    Science.gov (United States)

    Aschenbrenner, T.; Monetti, R.; Amigó, J. M.; Bunk, W.

    2013-06-01

    Ordinal symbolic dynamics has developed into a valuable method to describe complex systems. Recently, using the concept of transcripts, the coupling behaviour of systems was assessed, combining the properties of the symmetric group with information theoretic ideas. In this contribution, methods from the field of ordinal symbolic dynamics are applied to the characterisation of audio data. Coupling complexity between frequency bands of solo violin music, as a fingerprint of the instrument, is used for classification purposes within a support vector machine scheme. Our results suggest that coupling complexity is able to capture essential characteristics, sufficient to distinguish among different violins.

  8. Ordinance on protection from the harmful effects of X-radiation (X-ray Ordinance). As of January 8, 1987. 3. ed.

    International Nuclear Information System (INIS)

    Hinrichs, O.

    1992-01-01

    The German X-ray Ordinance (Roentgenverordnung) contains the main protective provisions applying to the field of X-ray equipment and sources of unwanted X radiation. It thus forms a complement to the German Radiation Protection Ordinance (Strahlenschutzverordnung). The X-ray Ordinance is based, as is the Radiation Protection Ordinance, on the German Nuclear Energy Act (Atomgesetz). It transposes the same Euratom Directives into national law, through which above all the limit values are defined. The current state of the X-ray Ordinance is that of the text promulgated on 8.01.1987 with the subsequent amendments, the last of which was adopted on 19.12.1990. The brochure also reproduces the Official Memorandum to the X-ray Ordinance, as this gives important indications for the legal construction of the Ordinance. (orig./HSCH) [de

  9. Some tools for the analysis of ordinal data

    African Journals Online (AJOL)

    nately the scientist is often misled by the use of numbers as symbols for the classes, with the result that the ... complete account of the theory concerned is to be found in. McCullagh & NeIder (1989) while Dobson ... Let z represent a number on the continuous scale, x a number on the ordinal scale. The data available will be ...

  10. extension staffs' perceptions of factors affecting co-ordination and ...

    African Journals Online (AJOL)

    Ian

    AFFECTING CO-ORDINATION AND PARTNERSHIPS IN. AGRICULTURAL EXTENSION SERVICES IN RAKAI. DISTRICT, UGANDA. E.E. Mwanje1, G.H. Düvel2 and M.N. Mangheni3. ABSTRACT. In Uganda's Rakai District,(with a population of about 400,000) there are over a dozen organizations involved in delivery of ...

  11. Ordinance No 190/1984 on the Radiation Protection Centre

    International Nuclear Information System (INIS)

    1984-01-01

    This ordinance was made in implementation of the 1983 Act setting up the Radiation Protection Centre and details the Centre's responsibilities and organisation. Its main duties include supervising observance of the 1957 Radiation Protection Act, as amended and the 1957 Atomic Energy Act as amended as well as of regulations made in accordance with both Acts. (NEA) [fr

  12. Economic and ordinal benefits of Hydrogen Energy Technology

    International Nuclear Information System (INIS)

    Giannantoni, C.; Zoli, M.

    2009-01-01

    A method for assessing economic, environmental and energy investments is particularly suited for hydrogen technologies, because it makes it possible to calculate business returns, negative externalities and, above all, the economic benefits to the citizens: the monetizable positive externalities and the ordinal benefits, i.e. those which cannot be reduced to a simple monetary value. [it

  13. Indoor smoking ordinances in workplaces and public places in Kansas.

    Science.gov (United States)

    Neuberger, John S; Davis, Ken; Nazir, Niaman; Dunton, Nancy; Winn, Kimberly; Jacquot, Sandy; Moler, Don

    2010-08-01

    The purpose of this study was to investigate the preferences of elected city officials regarding the need for a statewide clean indoor air law and to analyze the content of local smoking ordinances. A survey of elected officials in 57 larger Kansas cities obtained information on the perceived need for statewide legislation, venues to be covered, and motivating factors. Clean indoor air ordinances from all Kansas cities were analyzed by venue. The survey response rate was 190 out of 377 (50.4%) for elected officials. Over 70% of the respondents favored or strongly favored greater restrictions on indoor smoking. Sixty percent favored statewide legislation. Among these, over 80% favored restrictions in health care facilities, theaters, indoor sports arenas (including bowling alleys), restaurants, shopping malls, lobbies, enclosed spaces in outdoor arenas, and hotel/motel rooms. Officials who had never smoked favored a more restrictive approach. Employee and public health concerns were cited as influential by 76%-79% of respondents. Thirty-eight ordinances, covering over half of the state's population, were examined. They varied considerably in their exemptions. Official's attitudes toward smoking regulations were associated with their smoking status. The examination of existing ordinances revealed a piecemeal approach to smoking regulations.

  14. Co-ordinating humanitarian operations in peace support missions

    NARCIS (Netherlands)

    Rietjens, S.J.H.; Voordijk, Johannes T.; de Boer, S.J.

    2007-01-01

    Purpose – This paper seeks to contribute to a more effective co-ordination of humanitarian operations by military and civilian organizations involved in a peace support mission in response to a complex emergency. Design/methodology/approach – The information processing view, in particular

  15. Co-ordination Action on Ocean Energy (CA-OE)

    DEFF Research Database (Denmark)

    Tedd, James; Frigaard, Peter

    In October 2004, the Co-ordination Action on Ocean Energy (CA-OE) was launched, co-financed by the European Commission, under the Renewable Energy Technologies priority within the 6th Framework programme, contract number 502701, chaired by Kim Nielsen, Rambøll, Denmark. The project involves 41...

  16. Rate My Stake: Interpretation of Ordinal Stake Ratings

    Science.gov (United States)

    Patricia Lebow; Grant Kirker

    2014-01-01

    Ordinal rating systems are commonly employed to evaluate biodeterioration of wood exposed outdoors over long periods of time. The purpose of these ratings is to compare the durability of test systems to nondurable wood products or known durable wood products. There are many reasons why these systems have evolved as the chosen method of evaluation, including having an...

  17. When Can Information from Ordinal Scale Variables Be Integrated?

    Science.gov (United States)

    Kemp, Simon; Grace, Randolph C.

    2010-01-01

    Many theoretical constructs of interest to psychologists are multidimensional and derive from the integration of several input variables. We show that input variables that are measured on ordinal scales cannot be combined to produce a stable weakly ordered output variable that allows trading off the input variables. Instead a partial order is…

  18. Utility of Ordinal Scales Derived from Piaget's Observations.

    Science.gov (United States)

    Hunt, J. McVicker

    Arguments for the use of sequential ordinal scales in the observation of infants and young children are based on the tendency of traditional psychometric assessment to distract investigators from discerning structural and hierarchical aspects of development. Norm-referenced testing focuses on interindividual comparisons rather than developmental…

  19. Deterministic absorbed dose estimation in computed tomography using a discrete ordinates method

    International Nuclear Information System (INIS)

    Norris, Edward T.; Liu, Xin; Hsieh, Jiang

    2015-01-01

    Purpose: Organ dose estimation for a patient undergoing computed tomography (CT) scanning is very important. Although Monte Carlo methods are considered gold-standard in patient dose estimation, the computation time required is formidable for routine clinical calculations. Here, the authors instigate a deterministic method for estimating an absorbed dose more efficiently. Methods: Compared with current Monte Carlo methods, a more efficient approach to estimating the absorbed dose is to solve the linear Boltzmann equation numerically. In this study, an axial CT scan was modeled with a software package, Denovo, which solved the linear Boltzmann equation using the discrete ordinates method. The CT scanning configuration included 16 x-ray source positions, beam collimators, flat filters, and bowtie filters. The phantom was the standard 32 cm CT dose index (CTDI) phantom. Four different Denovo simulations were performed with different simulation parameters, including the number of quadrature sets and the order of Legendre polynomial expansions. A Monte Carlo simulation was also performed for benchmarking the Denovo simulations. A quantitative comparison was made of the simulation results obtained by the Denovo and the Monte Carlo methods. Results: The difference in the simulation results of the discrete ordinates method and those of the Monte Carlo methods was found to be small, with a root-mean-square difference of around 2.4%. It was found that the discrete ordinates method, with a higher order of Legendre polynomial expansions, underestimated the absorbed dose near the center of the phantom (i.e., low dose region). Simulations of the quadrature set 8 and the first order of the Legendre polynomial expansions proved to be the most efficient computation method in the authors’ study. The single-thread computation time of the deterministic simulation of the quadrature set 8 and the first order of the Legendre polynomial expansions was 21 min on a personal computer

  20. Lanthanide co-ordination frameworks: Opportunities and diversity

    International Nuclear Information System (INIS)

    Hill, Robert J.; Long, De-Liang; Hubberstey, Peter; Schroeder, Martin; Champness, Neil R.

    2005-01-01

    Significant successes have been made over recent years in preparing co-ordination framework polymers that show macroscopic material properties, but in the vast majority of cases this has been achieved with d-block metal-based systems. Lanthanide co-ordination frameworks also offer attractive properties in terms of their potential applications as luminescent, non-linear optical and porous materials. However, lanthanide-based systems have been far less studied to date than their d-block counterparts. One possible reason for this is that the co-ordination spheres of lanthanide cations are more difficult to control and, in the absence of design strategies for lanthanide co-ordination frameworks, it is significantly more difficult to target materials with specific properties. However, this article highlights some of the exciting possibilities that have emerged from the earliest investigations in this field with new topological families of compounds being discovered from relatively simple framework components, including unusual eight, seven and five-connected framework systems. Our own research, as well as others, is leading to a much greater appreciation of the factors that control framework formation and the resultant observed topologies of these polymers. As this understanding develops targeting particular framework types will become more straightforward and the development of designed polyfunctional materials more accessible. Thus, it can be seen that lanthanide co-ordination frameworks have the potential to open up previously unexplored directions for materials chemistry. This article focuses on the underlying concepts for the construction of these enticing and potentially highly important materials

  1. Transplantation of tendon-derived stem cells pre-treated with connective tissue growth factor and ascorbic acid in vitro promoted better tendon repair in a patellar tendon window injury rat model.

    Science.gov (United States)

    Lui, Pauline Po Yee; Wong, On Tik; Lee, Yuk Wa

    2016-01-01

    Treatment of tendon-derived stem cells (TDSCs) with connective tissue growth factor (CTGF) and ascorbic acid promoted their tenogenic differentiation. We investigated the effects of TDSCs pre-treated with CTGF and ascorbic acid on tendon repair in a patellar tendon window injury rat model. Green fluorescent protein-TDSCs (GFP-TDSCs) were pre-treated with or without CTGF and ascorbic acid for 2 weeks before transplantation. The patellar tendons of rats were injured and divided into three groups: fibrin glue-only group (control group), untreated and treated TDSC group. The rats were followed up until week 16. The treated TDSCs accelerated and enhanced the quality of tendon repair compared with untreated TDSCs up to week 8, which was better than that in the controls up to week 16 as shown by histology, ultrasound imaging and biomechanical test. The fibrils in the treated TDSC group showed better alignment and larger size compared with those in the control group at week 8 (P = 0.004). There was lower risk of ectopic mineralization after transplantation of treated or untreated TDSCs (all P ≤ 0.050). The transplanted cells proliferated and could be detected in the window wound up to weeks 2 to 4 and week 8 for the untreated and treated TDSC groups, respectively. The transplantation of TDSCs promoted tendon repair up to week 16, with CTGF and ascorbic acid pre-treatment showing the best results up to week 8. Pre-treatment of TDSCs with CTGF and ascorbic acid may be used to further enhance the rate and quality of tendon repair after injury. Copyright © 2015 International Society for Cellular Therapy. Published by Elsevier Inc. All rights reserved.

  2. The Effects of Various Configurations of Likert, Ordered Categorical, or Rating Scale Data on the Ordinal Logistic Regression Pseudo R-Squared Measure of Fit: The Case of the Cummulative Logit Model.

    Science.gov (United States)

    Zumbo, Bruno D.; Ochieng, Charles O.

    Many measures found in educational research are ordered categorical response variables that are empirical realizations of an underlying normally distributed variate. These ordered categorical variables are commonly referred to as Likert or rating scale data. Regression models are commonly fit using these ordered categorical variables as the…

  3. Parallel performance of the angular versus spatial domain decomposition for discrete ordinates transport methods

    International Nuclear Information System (INIS)

    Fischer, J.W.; Azmy, Y.Y.

    2003-01-01

    A previously reported parallel performance model for Angular Domain Decomposition (ADD) of the Discrete Ordinates method for solving multidimensional neutron transport problems is revisited for further validation. Three communication schemes: native MPI, the bucket algorithm, and the distributed bucket algorithm, are included in the validation exercise that is successfully conducted on a Beowulf cluster. The parallel performance model is comprised of three components: serial, parallel, and communication. The serial component is largely independent of the number of participating processors, P, while the parallel component decreases like 1/P. These two components are independent of the communication scheme, in contrast with the communication component that typically increases with P in a manner highly dependent on the global reduced algorithm. Correct trends for each component and each communication scheme were measured for the Arbitrarily High Order Transport (AHOT) code, thus validating the performance models. Furthermore, extensive experiments illustrate the superiority of the bucket algorithm. The primary question addressed in this research is: for a given problem size, which domain decomposition method, angular or spatial, is best suited to parallelize Discrete Ordinates methods on a specific computational platform? We address this question for three-dimensional applications via parallel performance models that include parameters specifying the problem size and system performance: the above-mentioned ADD, and a previously constructed and validated Spatial Domain Decomposition (SDD) model. We conclude that for large problems the parallel component dwarfs the communication component even on moderately large numbers of processors. The main advantages of SDD are: (a) scalability to higher numbers of processors of the order of the number of computational cells; (b) smaller memory requirement; (c) better performance than ADD on high-end platforms and large number of

  4. Assessing the radiological impact of past nuclear activities and events. Part of the IAEA/CEC co-ordinated research programme on the validation of environmental model predictions (VAMP)

    International Nuclear Information System (INIS)

    1994-07-01

    The report is a compilation of papers presented during the July 1993 Special Plenary Session of the VAMP (Validation of Environmental Model Predictions). The papers are grouped in 4 chapters: Assessment in the vicinity of nuclear weapons test sites (4 papers), Assessment in the vicinity of nuclear weapons production facilities (2 papers), Post-Chernobyl dose assessment studies (4 papers) and Assessment in the vicinity of dumped radioactive waste (1 paper). A separate abstract was prepared for each paper. Refs, figs and tabs

  5. Amendment of the Ordinance on the export and transit of goods

    International Nuclear Information System (INIS)

    1989-12-01

    This Ordinance amends the Annex of the Ordinance of 7 March 1983 on the export and transit of dangerous goods which lists the nuclear items, ie nuclear reactors, equipment and materials subject to export restrictions. The Ordinance came into force on 1 January 1990 (NEA) [fr

  6. 40 CFR 35.935-16 - Sewer use ordinance and evaluation/rehabilitation program.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Sewer use ordinance and evaluation...-Clean Water Act § 35.935-16 Sewer use ordinance and evaluation/rehabilitation program. (a) The grantee... sewer use ordinance, and the grantee is complying with the sewer system evaluation and rehabilitation...

  7. 49 CFR 397.3 - State and local laws, ordinances, and regulations.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false State and local laws, ordinances, and regulations... laws, ordinances, and regulations. Every motor vehicle containing hazardous materials must be driven and parked in compliance with the laws, ordinances, and regulations of the jurisdiction in which it is...

  8. Effect of moisture on pretreatment efficiency for anaerobic digestion of lignocellulosic substrates.

    Science.gov (United States)

    Peces, M; Astals, S; Mata-Alvarez, J

    2015-12-01

    The present study evaluates the effect of moisture in low-temperature and ultrasound pretreatment on lignocellulosic substrates anaerobic biodegradability, where brewer's spent grain was used as model substrate. Besides moisture content, low-temperature pretreatment was also evaluated in terms of temperature (60-80°C) and exposure time (12-72 h). Likewise, ultrasonication was also evaluated in terms of specific energy (1000-50,000 kJ kg TS(-1)). In addition, the effect of substrate particle size reduction by milling pretreatment was also considered. The results clearly demonstrated that substrate moisture (total solid concentration) is a significant parameter for pretreatment performance, although it has been rarely considered in pretreatment optimisation. Specifically, moisture optimisation increased the methane yield of brewer's spent grain by 6% for low-temperature pretreatment (60°C), and by 14% for ultrasound pretreatment (1000 kJ kg TS(-1)) towards the control (without pretreatment). In both pretreatments, the experimental optimum total solid concentration was 100 gTS kg(-1). Thus, lowering substrate moisture, a strategy suggested attaining energetic pretreatment feasibility, needs to be analysed as another pretreatment variable since it might have limited correlation. Finally, a preliminary energetic balance of the pretreatments under study showed that the extra methane production could not cover the energetic pretreatment expenses. Copyright © 2015 Elsevier Ltd. All rights reserved.

  9. Discrete-ordinate method with matrix exponential for a pseudo-spherical atmosphere: Scalar case

    International Nuclear Information System (INIS)

    Doicu, A.; Trautmann, T.

    2009-01-01

    We present a discrete-ordinate algorithm using the matrix-exponential solution for pseudo-spherical radiative transfer. Following the finite-element technique we introduce the concept of layer equation and formulate the discrete radiative transfer problem in terms of the level values of the radiance. The layer quantities are expressed by means of matrix exponentials, which are computed by using the matrix eigenvalue method and the Pade approximation. These solution methods lead to a compact and versatile formulation of the radiative transfer. Simulated nadir and limb radiances for an aerosol-loaded atmosphere and a cloudy atmosphere are presented along with a discussion of the model intercomparisons and timings

  10. Approximate albedo boundary conditions for energy multigroup X,Y-geometry discrete ordinates nuclear global calculations

    Energy Technology Data Exchange (ETDEWEB)

    Silva, Davi J.M.; Nunes, Carlos E.A.; Alves Filho, Hermes; Barros, Ricardo C., E-mail: davijmsilva@yahoo.com.br, E-mail: ceanunes@yahoo.com.br, E-mail: rcbarros@pq.cnpq.br [Secretaria Municipal de Educacao de Itaborai, RJ (Brazil); Universidade Estacio de Sa (UNESA), Rio de Janeiro, RJ (Brazil); Universidade do Estado do Rio de Janeiro (UERJ), Novra Friburgo, RJ (Brazil). Instituto Politecnico. Departamento de Modelagem Computacional

    2017-11-01

    Discussed here is the accuracy of approximate albedo boundary conditions for energy multigroup discrete ordinates (S{sub N}) eigenvalue problems in two-dimensional rectangular geometry for criticality calculations in neutron fission reacting systems, such as nuclear reactors. The multigroup (S{sub N}) albedo matrix substitutes approximately the non-multiplying media around the core, e.g., baffle and reflector, as we neglect the transverse leakage terms within these non-multiplying regions. Numerical results to a typical model problem are given to illustrate the accuracy versus the computer running time. (author)

  11. A guide to practical radiation protection in medicine. X-Ray Ordinance. Radiation Protection Ordinance. Practice-oriented hints, comments, text compilation

    International Nuclear Information System (INIS)

    Fiebich, M.; Nischelsky, J.E.; Pfeiff, H.; Westermann, K.

    2003-01-01

    This loose-leaf collection has been compiled for users who have to implement the X-ray Ordinance and the Radiation Protection Ordinance at their place of work. It presents all acts, ordinances, safety guides, regulations and recommendations of relevance in connection with the above two ordinances, as well as practical instructions and the full text of technical codes. Radiation protection officers and other persons in charge of radiation protection will find the references, information and advice needed to solve problems encountered. (orig.) [de

  12. Application of ordinal logistic regression analysis in determining risk factors of child malnutrition in Bangladesh

    Directory of Open Access Journals (Sweden)

    Das Sumonkanti

    2011-11-01

    Full Text Available Abstract Background The study attempts to develop an ordinal logistic regression (OLR model to identify the determinants of child malnutrition instead of developing traditional binary logistic regression (BLR model using the data of Bangladesh Demographic and Health Survey 2004. Methods Based on weight-for-age anthropometric index (Z-score child nutrition status is categorized into three groups-severely undernourished ( Results All the models determine that age of child, birth interval, mothers' education, maternal nutrition, household wealth status, child feeding index, and incidence of fever, ARI & diarrhoea were the significant predictors of child malnutrition; however, results of PPOM were more precise than those of other models. Conclusion These findings clearly justify that OLR models (POM and PPOM are appropriate to find predictors of malnutrition instead of BLR models.

  13. Stationary frozen-in co-ordinate system

    International Nuclear Information System (INIS)

    Pudovkin, M.I.; Semenov, V.S.

    1977-01-01

    The flow of a perfectly conductive fluid by a blunt body is considered from the topological point of view. It is shown that if the peculiarities of the flow of the ideal fluid are to be with the frozen-in conditions, one has to assume the existence of a stagnation line rather than a stagnation point. A stationary frozen-in co-ordinate system is discussed

  14. Three-dimensional discrete ordinates reactor assembly calculations on GPUs

    Energy Technology Data Exchange (ETDEWEB)

    Evans, Thomas M [ORNL; Joubert, Wayne [ORNL; Hamilton, Steven P [ORNL; Johnson, Seth R [ORNL; Turner, John A [ORNL; Davidson, Gregory G [ORNL; Pandya, Tara M [ORNL

    2015-01-01

    In this paper we describe and demonstrate a discrete ordinates sweep algorithm on GPUs. This sweep algorithm is nested within a multilevel comunication-based decomposition based on energy. We demonstrated the effectiveness of this algorithm on detailed three-dimensional critical experiments and PWR lattice problems. For these problems we show improvement factors of 4 6 over conventional communication-based, CPU-only sweeps. These sweep kernel speedups resulted in a factor of 2 total time-to-solution improvement.

  15. Topological properties of function spaces over ordinal spaces

    Czech Academy of Sciences Publication Activity Database

    Gabriyelyan, S.; Grebík, Jan; Kąkol, Jerzy; Zdomskyy, L.

    2017-01-01

    Roč. 111, č. 4 (2017), s. 1157-1161 ISSN 1578-7303 R&D Projects: GA ČR GF16-34860L Institutional support: RVO:67985840 Keywords : Ascoli * rK-space * ordinal space Subject RIV: BA - General Mathematics OBOR OECD: Pure mathematics Impact factor: 0.690, year: 2016 https://link. springer .com/article/10.1007%2Fs13398-016-0354-7

  16. A discrete-ordinates solution for a radiation therapy problem

    International Nuclear Information System (INIS)

    Goldschmidt, Gustavo Brun; Reichert, Janice Teresinha; Barichello, Liliane Basso

    2008-01-01

    A concise and accurate procedure for evaluating dose distribution, in a radiation therapy planning, is presented. The analytical discrete-ordinates method (ADO method) is used to develop a complete solution for a spectral dependent radiative transfer equation, in a one-dimensional medium, according to a multigroup scheme. Numerical results are presented for test problems, where the Klein-Nishina scattering kernel was used to describe the interaction processes. (author)

  17. Topological properties of function spaces over ordinal spaces

    Czech Academy of Sciences Publication Activity Database

    Gabriyelyan, S.; Grebík, Jan; Kąkol, Jerzy; Zdomskyy, L.

    2017-01-01

    Roč. 111, č. 4 (2017), s. 1157-1161 ISSN 1578-7303 R&D Projects: GA ČR GF16-34860L Institutional support: RVO:67985840 Keywords : Ascoli * rK-space * ordinal space Subject RIV: BA - General Mathematics OBOR OECD: Pure mathematics Impact factor: 0.690, year: 2016 https://link.springer.com/article/10.1007%2Fs13398-016-0354-7

  18. IAEA co-ordinated technical support programme to the NIS

    International Nuclear Information System (INIS)

    Olsen, R.; Murakami, K.; Blacker, C.; Sharma, S.K.

    1999-01-01

    With most Newly Independent States (NIS) of the former Soviet Union becoming parties to the Non-Proliferation Treaty as Non-Nuclear Weapon States, there has been an acute need in these states for considerable assistance for the establishment of the necessary structure and resources to ensure that their commitments to non-proliferation are fully implemented in a timely manner. A number of IAEA Member States have offered and are now providing assistance to the NIS on a bilateral level to set up an appropriate State System of Accounting and Control (SSAC) which includes Import/Export Control and Physical Protection of Nuclear Material in each state. The IAEA and these Member States established the Co-ordinated Technical Support Programme (CTSP) to ensure that the support given to the NIS was done in a co-ordinated and transparent manner and to avoid duplication of effort. The IAEA has played a coordinating role for the past 5 years by helping to identify detailed needs in individual States, by providing a platform for Member States to identify areas where they could provide the optimum support, and in developing and preparing the Co-ordinated Technical Support Plans. The IAEA organises annual meetings in Vienna attended by all donor and recipient countries to review the focus and implementation status of the co-ordinated technical support activities. A position statement is made by each donor and recipient country, and views and experiences are exchanged. The contents of the CTSPs and the role of the Agency in monitoring the progress of the individual tasks are reviewed in this paper. A summary comparing the implementation status of the Programme by each country is presented. (author)

  19. Effects of Pretreatments in Convective Dehydration of Rosehip (Rosa eglanteria

    Directory of Open Access Journals (Sweden)

    Alejandra Mabellini

    2012-04-01

    Full Text Available The aim of this work was to experimentally determine drying curves for thin layer and bed drying of rosehip fruits, with and without pretreatments, to reduce processing times as a function of drying air operating variables, to propose dehydration kinetics of fruits and to determine its kinetic parameters for further use within drying simulation software. Fruits were pre-treated both chemically and mechanically, which included dipping the fruits in NaOH and ethyl oleate solutions; and cutting or perforating the fruit cuticle, respectively. Simulation models were then adopted to fit the kinetics drying data considering fruit volume shrinkage. These simple models minimized the calculation time during the simulation of deep-bed driers. Results show that pre-treatments reduced processing times up to 57%, and evaluated models satisfactorily predicted the drying of rosehip fruit. Effective mass diffusion coefficients were up to 4-fold greater when fruit was submitted to mechanical pretreatments.

  20. Classification of forested wetlands using ordination of multitemporal Landsat reflectance

    Science.gov (United States)

    Keim, R. F.; Zoller, J. A.; Braud, D. H.

    2007-12-01

    There are important limitations in interpreting satellite imagery in dynamic environments. In forested wetlands, where flooding and aquatic vegetation vary temporally, a multitemporal approach is needed for extracting stable patterns. We used field measurements of forest composition and structure and seven cloud-free Landsat images from a time span of six years to classify forest vigor in 95,000 ha of cypress-tupelo forested wetlands surrounding Lake Verret in southern Louisiana. A principal component (PCA) ordination of the reflectance in Landsat bands 3/4/5 for each image was the basis of the classification. No single Landsat band or image dominated the first few PCs, so that the multitemporal and multispectral aspect of the data were fully expressed in the ordination. Each Landsat pixel was classified as to forest vigor according to its scores in the first two PCs by comparing pixel scores to those associated with field plots. The reflectance PCA, and thus the classification, was directly interpretable in terms of ecosystem structure because the scored in the first two PCs in field-plot pixels were correlated to field measurements of forest structure, such as leaf area index, stand density, and understory composition, and because the field plots occupied interpretable regions of ordination space.

  1. A discrete ordinates approximation to the neutron transport equation applied to generalized geometries

    Energy Technology Data Exchange (ETDEWEB)

    DeHart, Mark David [Texas A & M Univ., College Station, TX (United States)

    1992-12-01

    A method for applying the discrete ordinates method for solution of the neutron transport equation in arbitary two-dimensional meshes has been developed. The finite difference approach normally used to approximate spatial derivatives in extrapolating angular fluxes across a cell is replaced by direct solution of the characteristic form of the transport equation for each discrete direction. Thus, computational cells are not restricted to the traditional shape of a mesh element within a given coordinate system. However, in terms of the treatment of energy and angular dependencies, this method resembles traditional discrete ordinates techniques. Using the method developed here, a general two-dimensional space can be approximated by an irregular mesh comprised of arbitrary polygons. The present work makes no assumptions about the orientations or the number of sides in a given cell, and computes all geometric relationships between each set of sides in each cell for each discrete direction. A set of non-reentrant polygons can therefore be used to represent any given two dimensional space. Results for a number of test problems have been compared to solutions obtained from traditional methods, with good agreement. Comparisons include benchmarks against analytical results for problems with simple geometry, as well numerical results obtained from traditional discrete ordinates methods by applying the ANISN and TWOTRAN computer programs. Numerical results were obtained for problems ranging from simple one-dimensional geometry to complicated multidimensional configurations. These results have demonstrated the ability of the developed method to closely approximate complex geometrical configurations and to obtain accurate results for problems that are extremely difficult to model using traditional methods.

  2. On the spectrum of the one-speed slab-geometry discrete ordinates operator in neutron transport theory

    International Nuclear Information System (INIS)

    Abreu, Marcos Pimenta de

    1998-01-01

    We describe a numerical method applied to the first-order form of one-speed slab-geometry discrete ordinates equations modelling time-independent neutron transport problems with anisotropic scattering, with no interior source and defined in a nonmultiplying homogeneous host medium. Our numerical method is concerned with the generation of the spectrum and of a vector basis for the null space of the one-speed slab-geometry discrete ordinates operator. Moreover, it allows us to overcome the difficulties introduced in previous methods by anisotropic scattering and by angular quadrature sets of high order. To illustrate the positive features of our numerical method, we present numerical results for one-speed slab-geometry neutron transport model problems with anisotropic scattering

  3. Handbook for calculations of nuclear reaction data. Reference input parameter library. Final report of a co-ordinated research project

    International Nuclear Information System (INIS)

    1998-08-01

    With the aim to develop an internationally recognised input parameter library with the contributions from all major nuclear data laboratories, IAEA initiated and co-ordinated a Co-ordinated Research Project (CRP) entitled 'Development of Reference Input Parameter Library for Nuclear Model calculations of Nuclear Data (Phase 1: Starter File)'. Between 1994 and 1997 the following two major results were produced: complete electronic Reference Input Parameter Library (Starter File) available to users cost-free and this Handbook containing a detailed description of the Library. Starter file contains input parameters for calculations of nuclear reaction cross sections arranged in seven segments (directories): Atomic masses and deformations, Discrete level schemes, Average neutron resonance parameters, Optical model parameters, Level densities, Gamma-ray strength functions, Continuum angular distributions. This book contains ten papers describing the cited subjects, each with a separate abstract

  4. Celebrating difference: a co - ordinate model of schooling

    African Journals Online (AJOL)

    QuickSilver

    There are female and male brains that don't do this. This is a general noted tendency. Why the brains are different is explained by human and natu- ral history and the production of hormones in utero and at pu- berty. We are going to focus on the puberty years, where differences are very noticeable. IMPLICATIONS. There is ...

  5. Using ordinal regression modelling to evaluate the satisfaction of ...

    African Journals Online (AJOL)

    Data analysis involved both descriptive and inferential analysis. The factors that were found to influence the satisfaction of the JKUAT Faculty of Science students were four; service delivery at the department office, the library services, accommodation facilities in the university hostels and accommodation facilities outside the ...

  6. A Fuzzy Group Decision Making Model for Ordinal Peer Assessment

    Science.gov (United States)

    Capuano, Nicola; Loia, Vincenzo; Orciuoli, Francesco

    2017-01-01

    Massive Open Online Courses (MOOCs) are becoming an increasingly popular choice for education but, to reach their full extent, they require the resolution of new issues like assessing students at scale. A feasible approach to tackle this problem is peer assessment, in which students also play the role of assessor for assignments submitted by…

  7. Why overlearned sequences are special: distinct neural networks for ordinal sequences

    Science.gov (United States)

    Pariyadath, Vani; Plitt, Mark H.; Churchill, Sara J.; Eagleman, David M.

    2012-01-01

    Several observations suggest that overlearned ordinal categories (e.g., letters, numbers, weekdays, months) are processed differently than non-ordinal categories in the brain. In synesthesia, for example, anomalous perceptual experiences are most often triggered by members of ordinal categories (Rich et al., 2005; Eagleman, 2009). In semantic dementia (SD), the processing of ordinal stimuli appears to be preserved relative to non-ordinal ones (Cappelletti et al., 2001). Moreover, ordinal stimuli often map onto unconscious spatial representations, as observed in the SNARC effect (Dehaene et al., 1993; Fias, 1996). At present, little is known about the neural representation of ordinal categories. Using functional neuroimaging, we show that words in ordinal categories are processed in a fronto-temporo-parietal network biased toward the right hemisphere. This differs from words in non-ordinal categories (such as names of furniture, animals, cars, and fruit), which show an expected bias toward the left hemisphere. Further, we find that increased predictability of stimulus order correlates with smaller regions of BOLD activation, a phenomenon we term prediction suppression. Our results provide new insights into the processing of ordinal stimuli, and suggest a new anatomical framework for understanding the patterns seen in synesthesia, unconscious spatial representation, and SD. PMID:23267320

  8. Why Overlearned Sequences are Special: Distinct Neural Networks for Ordinal Sequences

    Directory of Open Access Journals (Sweden)

    Vani ePariyadath

    2012-12-01

    Full Text Available Several observations suggest that overlearned ordinal categories (e.g., letters, numbers, weekdays, months are processed differently than non-ordinal categories in the brain. In synesthesia, for example, anomalous perceptual experiences are most often triggered by members of ordinal categories (Rich et al., 2005; Eagleman, 2009. In semantic dementia, the processing of ordinal stimuli appears to be preserved relative to non-ordinal ones (Cappelletti et al., 2001. Moreover, ordinal stimuli often map onto unconscious spatial representations, as observed in the SNARC effect (Dehaene et al, 1993; Fias, 1996. At present, little is known about the neural representation of ordinal categories. Using functional neuroimaging, we show that words in ordinal categories are processed in a fronto-temporo-parietal network biased toward the right hemisphere. This differs from words in non-ordinal categories (such as names of furniture, animals, cars and fruit, which show an expected bias toward the left hemisphere. Further, we find that increased predictability of stimulus order correlates with smaller regions of BOLD activation, a phenomenon we term prediction suppression. Our results provide new insights into the processing of ordinal stimuli, and suggest a new anatomical framework for understanding the patterns seen in synesthesia, unconscious spatial representation, and semantic dementia.

  9. Collections of laws and ordinances concerning radiation injury prevention as of July 24, 1981

    International Nuclear Information System (INIS)

    Tsuruta, Takao

    1981-01-01

    There are laws, government and ministerial ordinances and notifications, each of them bears a definite role, and the contents of the legal regulation on a certain range of matter are determined by their close interrelation and mutual supplementation. Many laws and ordinances concerning atomic energy also form a legal system under such mutual relation. The Atomic Energy Act is positioned at its top, and the main part related to radiation injury prevention comprises a law, two ordinances, a regulation and a notification. Such relationship of individual laws and ordinances is mostly shown in lower rank laws and ordinances. In Chapter 1 of this book, the Atomic Energy Act and the government ordinance concerning the definition of nuclear fuel materials, nuclear raw materials, nuclear reactors and radiation are described. In Chapter 2, the law concerning prevention of radiation injuries due to radiactive isotopes and others, the ordinances and eight notifications closely related to them are collected. In Chapter 3, other related laws and ordinances are gathered. To understand the laws and ordinances synthetically and systematically, the provisions of different laws and ordinances, which are mutually related, are arranged together showing their relation. (Kako, I.)

  10. Processes for pretreating lignocellulosic biomass: A review

    Energy Technology Data Exchange (ETDEWEB)

    McMillan, J.D.

    1992-11-01

    This paper reviews existing and proposed pretreatment processes for biomass. The focus is on the mechanisms by which the various pretreatments act and the influence of biomass structure and composition on the efficacy of particular pretreatment techniques. This analysis is used to identify pretreatment technologies and issues that warrant further research.

  11. Mapping of the DLQI scores to EQ-5D utility values using ordinal logistic regression.

    Science.gov (United States)

    Ali, Faraz Mahmood; Kay, Richard; Finlay, Andrew Y; Piguet, Vincent; Kupfer, Joerg; Dalgard, Florence; Salek, M Sam

    2017-11-01

    The Dermatology Life Quality Index (DLQI) and the European Quality of Life-5 Dimension (EQ-5D) are separate measures that may be used to gather health-related quality of life (HRQoL) information from patients. The EQ-5D is a generic measure from which health utility estimates can be derived, whereas the DLQI is a specialty-specific measure to assess HRQoL. To reduce the burden of multiple measures being administered and to enable a more disease-specific calculation of health utility estimates, we explored an established mathematical technique known as ordinal logistic regression (OLR) to develop an appropriate model to map DLQI data to EQ-5D-based health utility estimates. Retrospective data from 4010 patients were randomly divided five times into two groups for the derivation and testing of the mapping model. Split-half cross-validation was utilized resulting in a total of ten ordinal logistic regression models for each of the five EQ-5D dimensions against age, sex, and all ten items of the DLQI. Using Monte Carlo simulation, predicted health utility estimates were derived and compared against those observed. This method was repeated for both OLR and a previously tested mapping methodology based on linear regression. The model was shown to be highly predictive and its repeated fitting demonstrated a stable model using OLR as well as linear regression. The mean differences between OLR-predicted health utility estimates and observed health utility estimates ranged from 0.0024 to 0.0239 across the ten modeling exercises, with an average overall difference of 0.0120 (a 1.6% underestimate, not of clinical importance). This modeling framework developed in this study will enable researchers to calculate EQ-5D health utility estimates from a specialty-specific study population, reducing patient and economic burden.

  12. Radiation Protection Ordinance 1989. Supplement with Radiation Protection Register Ordinance, general administration regulation pursuant to Sect. 45 Radiation Protection Ordinance, general administration regulation pursuant to Sect. 62 sub-sect. radiation passport

    International Nuclear Information System (INIS)

    Veith, H.M.

    1990-01-01

    The addendum contains regulations issued supplementary to the Radiation Protection Ordinance: The Radiation Protection Register as of April 3, 1990 including the law on the setting up of a Federal Office on Radiation Protection; the general administration regulation pursuant to Sect. 45 Radiation Protection Ordinance as of February 21, 1990; the general administration regulation pursuant to Sect. 62 sub-sect. 2 Radiation Protection Ordinance as of May 3, 1990 (AVV Radiation passport). The volume contains, apart from the legal texts, the appropriate decision by the Bundesrat, the official explanation from the Bundestag Publications as well as a comprehensive introduction into the new legal matter. (orig.) [de

  13. Compliance to two city convenience store ordinance requirements.

    Science.gov (United States)

    Chaumont Menéndez, Cammie K; Amandus, Harlan E; Wu, Nan; Hendricks, Scott A

    2016-04-01

    Robbery-related homicides and assaults are the leading cause of death in retail businesses. Robbery reduction approaches focus on compliance to Crime Prevention Through Environmental Design (CPTED) guidelines. We evaluated the level of compliance to CPTED guidelines specified by convenience store safety ordinances effective in 2010 in Dallas and Houston, Texas, USA. Convenience stores were defined as businesses less than 10 000 square feet that sell grocery items. Store managers were interviewed for store ordinance requirements from August to November 2011, in a random sample of 594 (289 in Dallas, 305 in Houston) convenience stores that were open before and after the effective dates of their city's ordinance. Data were collected in 2011 and analysed in 2012-2014. Overall, 9% of stores were in full compliance, although 79% reported being registered with the police departments as compliant. Compliance was consistently significantly higher in Dallas than in Houston for many requirements and by store type. Compliance was lower among single owner-operator stores compared with corporate/franchise stores. Compliance to individual requirements was lowest for signage and visibility. Full compliance to the required safety measures is consistent with industry 'best practices' and evidence-based workplace violence prevention research findings. In Houston and Dallas compliance was higher for some CPTED requirements but not the less costly approaches that are also the more straightforward to adopt. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  14. An ordination of life histories using morphological proxies: capital vs. income breeding in insects.

    Science.gov (United States)

    Davis, Robert B; Javoiš, Juhan; Kaasik, Ants; Õunap, Erki; Tammaru, Toomas

    2016-08-01

    Predictive classifications of life histories are essential for evolutionary ecology. While attempts to apply a single approach to all organisms may be overambitious, recent advances suggest that more narrow ordination schemes can be useful. However, these schemes mostly lack easily observable proxies of the position of a species on respective axes. It has been proposed that, in insects, the degree of capital (vs. income) breeding, reflecting the importance of adult feeding for reproduction, correlates with various ecological traits at the level of among-species comparison. We sought to prove these ideas via rigorous phylogenetic comparative analyses. We used experimentally derived life-history data for 57 species of European Geometridae (Lepidoptera), and an original phylogenetic reconstruction. The degree of capital breeding was estimated based on morphological proxies, including relative abdomen size of females. Applying Brownian-motion-based comparative analyses (with an original update to include error estimates), we demonstrated the associations between the degree of capital breeding and larval diet breadth, sexual size dimorphism, and reproductive season. Ornstein-Uhlenbeck model based phylogenetic analysis suggested a causal relationship between the degree of capital breeding and diet breadth. Our study indicates that the gradation from capital to income breeding is an informative axis to ordinate life-history strategies in flying insects which are affected by the fecundity vs. mobility trade off, with the availability of easy to record proxies contributing to its predictive power in practical contexts. © 2016 by the Ecological Society of America.

  15. Seattle's minimum wage ordinance did not affect supermarket food prices by food processing category.

    Science.gov (United States)

    Spoden, Amanda L; Buszkiewicz, James H; Drewnowski, Adam; Long, Mark C; Otten, Jennifer J

    2018-02-07

    To examine the impacts of Seattle's minimum wage ordinance on food prices by food processing category. Supermarket food prices were collected for 106 items using a University of Washington Center for Public Health Nutrition market basket at affected and unaffected supermarket chain stores at three times: March 2015 (1-month pre-policy enactment), May 2015 (1-month post-policy enactment) and May 2016 (1-year post-policy enactment). Food items were categorized into four food processing groups, from minimally to ultra-processed. Data were analysed across time using a multilevel, linear difference-in-differences model at the store and price level stratified by level of food processing. Six large supermarket chain stores located in Seattle ('intervention') affected by the policy and six same-chain but unaffected stores in King County ('control'), Washington, USA. One hundred and six food and beverage items. The largest change in average price by food item was +$US 0·53 for 'processed foods' in King County between 1-month post-policy and 1-year post-policy enactment (P minimum wage ordinance by level of the food's processing. These results suggest that the early implementation of a city-level minimum wage policy does not alter supermarket food prices by level of food processing.

  16. Prehospital vital signs can predict pain severity: analysis using ordinal logistic regression.

    Science.gov (United States)

    Bendall, Jason C; Simpson, Paul M; Middleton, Paul M

    2011-12-01

    To determine whether vital signs in patients suffering from acute pain in the out-of-hospital setting have any association with pain severity measured using an ordinal pain scale. We conducted a retrospective analysis of over 53 000 adult patients aged between 16 and 100 years, who presented to paramedics complaining of acute pain between 1 January 2004 and 30 November 2006. Simple correlation (Spearman's) and ordinal logistic regression techniques were used to create a proportional odds model to explore the relationship between patient-reported pain score and initial vital signs including respiratory rate, pulse rate and blood pressure. There was a weak but significant correlation between respiratory rate and initial pain score (R=0.15, Plogistic regression. In adults, a respiratory rate of 25 breaths/min or more was the most important predictor of having more severe pain. Tachycardia and systolic hypertension may also be important in younger and older patients, respectively. Simple correlation fails to show clinically important associations between prehospital vital signs and pain severity.

  17. Co-ordinate regulation of genes involved in storage lipid mobilization in Arabidopsis thaliana.

    Science.gov (United States)

    Rylott, E L; Hooks, M A; Graham, I A

    2001-05-01

    Molecular genetic approaches in the model plant Arabidopsis thaliana (Col0) are shedding new light on the role and control of the pathways associated with the mobilization of lipid reserves during oilseed germination and post-germinative growth. Numerous independent studies have reported on the expression of individual genes encoding enzymes from the three major pathways: beta-oxidation, the glyoxylate cycle and gluconeogenesis. However, a single comprehensive study of representative genes and enzymes from the different pathways in a single plant species has not been done. Here we present results from Arabidopsis that demonstrate the co-ordinate regulation of gene expression and enzyme activities for the acyl-CoA oxidase- and 3-ketoacyl-CoA thiolase-mediated steps of beta-oxidation, the isocitrate lyase and malate synthase steps of the glyoxylate cycle and the phosphoenolpyruvate carboxykinase step of gluconeogenesis. The mRNA abundance and enzyme activities increase to a peak at stage 2, 48 h after the onset of seed germination, and decline thereafter either to undetectable levels (for malate synthase and isocitrate lyase) or low basal levels (for the genes of beta-oxidation and gluconeogenesis). The co-ordinate induction of all these genes at the onset of germination raises the possibility that a global regulatory mechanism operates to induce the expression of genes associated with the mobilization of storage reserves during the heterotrophic growth period.

  18. Modifications Of Discrete Ordinate Method For Computations With High Scattering Anisotropy: Comparative Analysis

    Science.gov (United States)

    Korkin, Sergey V.; Lyapustin, Alexei I.; Rozanov, Vladimir V.

    2012-01-01

    A numerical accuracy analysis of the radiative transfer equation (RTE) solution based on separation of the diffuse light field into anisotropic and smooth parts is presented. The analysis uses three different algorithms based on the discrete ordinate method (DOM). Two methods, DOMAS and DOM2+, that do not use the truncation of the phase function, are compared against the TMS-method. DOMAS and DOM2+ use the Small-Angle Modification of RTE and the single scattering term, respectively, as an anisotropic part. The TMS method uses Delta-M method for truncation of the phase function along with the single scattering correction. For reference, a standard discrete ordinate method, DOM, is also included in analysis. The obtained results for cases with high scattering anisotropy show that at low number of streams (16, 32) only DOMAS provides an accurate solution in the aureole area. Outside of the aureole, the convergence and accuracy of DOMAS, and TMS is found to be approximately similar: DOMAS was found more accurate in cases with coarse aerosol and liquid water cloud models, except low optical depth, while the TMS showed better results in case of ice cloud.

  19. Implementing the Open Method of Co-ordination in Pensions

    Directory of Open Access Journals (Sweden)

    Jarosław POTERAJ

    2009-01-01

    Full Text Available The article presents an insight into the European Union Open Methodof Co-ordination (OMC in area of pension. The author’s goal was to presentthe development and the effects of implementation the OMC. The introductionis followed by three topic paragraphs: 1. the OMC – step by step, 2. theevaluation of the OMC, and 3. the effects of OMC implementation. In thesummary, the author highlights as except of advantages there are alsodisadvantages of the implementation of the OMC, and there are many doubtsexist in the context of efficiency of performing that method in the future.

  20. Diffusion-synthetic acceleration methods for discrete-ordinates problems

    International Nuclear Information System (INIS)

    Larsen, E.W.

    1984-01-01

    The diffusion-synthetic acceleration (DSA) method is an iterative procedure for obtaining numerical solutions of discrete-ordinates problems. The DSA method is operationally more complicated than the standard source-iteration (SI) method, but if encoded properly it converges much more rapidly, especially for problems with diffusion-like regions. In this article we describe the basic ideas behind the DSA method and give a (roughly chronological) review of its long development. We conclude with a discussion which covers additional topics, including some remaining open problems an the status of current efforts aimed at solving these problems

  1. Ordinance of 14 March 1983 concerning the Federal Commission for the Safety of Nuclear Installations

    International Nuclear Information System (INIS)

    1983-01-01

    The Frederal Council issued a new Ordinance concerning the Federal Commission for the Safety of Nuclear Installations. This Ordinance replaces an Ordinance of 13 June 1960 and takes into account the distribution of tasks decided several years ago between the Commission, which operates on a part-time basis, and the principal Division for the Safety of Nuclear Installations attached to the Federal Office of Energy. (NEA) [fr

  2. Tank Focus Area pretreatment activities

    International Nuclear Information System (INIS)

    McGinnis, C.P.; Welch, T.D.; Manke, K.L.

    1997-01-01

    Plans call for the high-level wastes to be retrieved from the tanks and immobilized in a stable waste form suitable for long-term isolation. Chemistry and chemical engineering operations are required to retrieve the wastes, to condition the wastes for subsequent steps, and to reduce the costs of the waste management enterprise. Pretreatment includes those processes between retrieval and immobilization, and includes preparation of suitable feed material for immobilization and separations to partition the waste into streams that yield lower life-cycle costs. Some of the technologies being developed by the Tank Focus Area (TFA) to process these wastes are described. These technologies fall roughly into three areas: (1) solid/liquid separation (SLS), (2) sludge pretreatment, and (3) supernate pretreatment

  3. Model-based optimization and scale-up of multi-feed simultaneous saccharification and co-fermentation of steam pre-treated lignocellulose enables high gravity ethanol production.

    Science.gov (United States)

    Wang, Ruifei; Unrean, Pornkamol; Franzén, Carl Johan

    2016-01-01

    High content of water-insoluble solids (WIS) is required for simultaneous saccharification and co-fermentation (SSCF) operations to reach the high ethanol concentrations that meet the techno-economic requirements of industrial-scale production. The fundamental challenges of such processes are related to the high viscosity and inhibitor contents of the medium. Poor mass transfer and inhibition of the yeast lead to decreased ethanol yield, titre and productivity. In the present work, high-solid SSCF of pre-treated wheat straw was carried out by multi-feed SSCF which is a fed-batch process with additions of substrate, enzymes and cells, integrated with yeast propagation and adaptation on the pre-treatment liquor. The combined feeding strategies were systematically compared and optimized using experiments and simulations. For high-solid SSCF process of SO2-catalyzed steam pre-treated wheat straw, the boosted solubilisation of WIS achieved by having all enzyme loaded at the beginning of the process is crucial for increased rates of both enzymatic hydrolysis and SSCF. A kinetic model was adapted to simulate the release of sugars during separate hydrolysis as well as during SSCF. Feeding of solid substrate to reach the instantaneous WIS content of 13 % (w/w) was carried out when 60 % of the cellulose was hydrolysed, according to simulation results. With this approach, accumulated WIS additions reached more than 20 % (w/w) without encountering mixing problems in a standard bioreactor. Feeding fresh cells to the SSCF reactor maintained the fermentation activity, which otherwise ceased when the ethanol concentration reached 40-45 g L(-1). In lab scale, the optimized multi-feed SSCF produced 57 g L(-1) ethanol in 72 h. The process was reproducible and resulted in 52 g L(-1) ethanol in 10 m(3) scale at the SP Biorefinery Demo Plant. SSCF of WIS content up to 22 % (w/w) is reproducible and scalable with the multi-feed SSCF configuration and model-aided process

  4. Biologically Pre-Treated Habitation Waste Water as a Sustainable Green Urine Pre-Treat Solution

    Science.gov (United States)

    Jackson, W. Andrew; Thompson, Bret; Sevanthi, Ritesh; Morse, Audra; Meyer, Caitlin; Callahan, Michael

    2017-01-01

    The ability to recover water from urine and flush water is a critical process to allow long term sustainable human habitation in space or bases on the moon or mars. Organic N present as urea or similar compounds can hydrolyze producing free ammonia. This reaction results in an increase in the pH converting ammonium to ammonia which is volatile and not removed by distillation. The increase in pH will also cause precipitation reactions to occur. In order to prevent this, urine on ISS is combined with a pretreat solution. While use of a pretreatment solution has been successful, there are numerous draw backs including: storage and use of highly hazardous solutions, limitations on water recovery (less than 85%), and production of brine with pore dewatering characteristics. We evaluated the use of biologically treated habitation wastewaters (ISS and early planetary base) to replace the current pretreat solution. We evaluated both amended and un-amended bioreactor effluent. For the amended effluent, we evaluated "green" pretreat chemicals including citric acid and citric acid amended with benzoic acid. We used a mock urine/air separator modeled after the urine collection assembly on ISS. The urine/air separator was challenged continually for >6 months. Depending on the test point, the separator was challenged daily with donated urine and flushed with amended or un-amended reactor effluent. We monitored the pH of the urine, flush solution and residual pH in the urine/air separator after each urine event. We also evaluated solids production and biological growth. Our results support the use of both un-amended and amended bioreactor effluent to maintain the operability of the urine /air separator. The ability to use bioreactor effluent could decrease consumable cost, reduce hazards associated with current pre-treat chemicals, allow other membrane based desalination processes to be utilized, and improve brine characteristics.

  5. Spherical polar co-ordinate calculations of induced fields in the retina and head for applied magnetic fields at 50 Hz

    Energy Technology Data Exchange (ETDEWEB)

    Dimbylow, Peter, E-mail: peter.dimbylow@hpa.org.uk [Health Protection Agency, Chilton, Didcot, Oxon OX11 0RQ (United Kingdom)

    2011-07-21

    This paper sets out to explore the effects of voxel resolution, from 2 mm down to 0.1 mm for Cartesian co-ordinates and the differences between Cartesian and spherical polar co-ordinates for a standardized test-bed model of the eye. This model was taken from the work of Yoriyaz et al (2005 Radiat. Prot. Dosim. 115 316-9) who have developed a detailed geometric description of the eye including choroid, retina, sclera, lens, cornea, anterior chamber, vitreous humour and optic nerve for ophthalmic brachytherapy. The spherical co-ordinate model has radial and angular steplengths of 0.1 mm and 0.25{sup 0}, respectively. The current density averaged over 1 cm{sup 2} and the 99th percentile value of the induced electric field have been calculated in the retina and central nervous system for uniform magnetic fields. The Cartesian co-ordinate calculations proceed in a sequence of grids at 2, 1, 0.5, 0.2 and 0.1 mm resolution with the potentials from the previous calculation at a coarser grid providing the boundary conditions on the finer grid. The 0.2 mm grid provides the boundary conditions for the spherical polar calculations. Comparisons are made with the International Commission on Non-Ionizing Radiation Protection reference levels.

  6. Spherical polar co-ordinate calculations of induced fields in the retina and head for applied magnetic fields at 50 Hz.

    Science.gov (United States)

    Dimbylow, Peter

    2011-07-21

    This paper sets out to explore the effects of voxel resolution, from 2 mm down to 0.1 mm for Cartesian co-ordinates and the differences between Cartesian and spherical polar co-ordinates for a standardized test-bed model of the eye. This model was taken from the work of Yoriyaz et al (2005 Radiat. Prot. Dosim. 115 316-9) who have developed a detailed geometric description of the eye including choroid, retina, sclera, lens, cornea, anterior chamber, vitreous humour and optic nerve for ophthalmic brachytherapy. The spherical co-ordinate model has radial and angular steplengths of 0.1 mm and 0.25°, respectively. The current density averaged over 1 cm(2) and the 99th percentile value of the induced electric field have been calculated in the retina and central nervous system for uniform magnetic fields. The Cartesian co-ordinate calculations proceed in a sequence of grids at 2, 1, 0.5, 0.2 and 0.1 mm resolution with the potentials from the previous calculation at a coarser grid providing the boundary conditions on the finer grid. The 0.2 mm grid provides the boundary conditions for the spherical polar calculations. Comparisons are made with the International Commission on Non-Ionizing Radiation Protection reference levels.

  7. Spherical polar co-ordinate calculations of induced fields in the retina and head for applied magnetic fields at 50 Hz

    International Nuclear Information System (INIS)

    Dimbylow, Peter

    2011-01-01

    This paper sets out to explore the effects of voxel resolution, from 2 mm down to 0.1 mm for Cartesian co-ordinates and the differences between Cartesian and spherical polar co-ordinates for a standardized test-bed model of the eye. This model was taken from the work of Yoriyaz et al (2005 Radiat. Prot. Dosim. 115 316-9) who have developed a detailed geometric description of the eye including choroid, retina, sclera, lens, cornea, anterior chamber, vitreous humour and optic nerve for ophthalmic brachytherapy. The spherical co-ordinate model has radial and angular steplengths of 0.1 mm and 0.25 0 , respectively. The current density averaged over 1 cm 2 and the 99th percentile value of the induced electric field have been calculated in the retina and central nervous system for uniform magnetic fields. The Cartesian co-ordinate calculations proceed in a sequence of grids at 2, 1, 0.5, 0.2 and 0.1 mm resolution with the potentials from the previous calculation at a coarser grid providing the boundary conditions on the finer grid. The 0.2 mm grid provides the boundary conditions for the spherical polar calculations. Comparisons are made with the International Commission on Non-Ionizing Radiation Protection reference levels.

  8. Three ancient hormonal cues co-ordinate shoot branching in a moss.

    Science.gov (United States)

    Coudert, Yoan; Palubicki, Wojtek; Ljung, Karin; Novak, Ondrej; Leyser, Ottoline; Harrison, C Jill

    2015-03-25

    Shoot branching is a primary contributor to plant architecture, evolving independently in flowering plant sporophytes and moss gametophytes. Mechanistic understanding of branching is largely limited to flowering plants such as Arabidopsis, which have a recent evolutionary origin. We show that in gametophytic shoots of Physcomitrella, lateral branches arise by re-specification of epidermal cells into branch initials. A simple model co-ordinating the activity of leafy shoot tips can account for branching patterns, and three known and ancient hormonal regulators of sporophytic branching interact to generate the branching pattern- auxin, cytokinin and strigolactone. The mode of auxin transport required in branch patterning is a key divergence point from known sporophytic pathways. Although PIN-mediated basipetal auxin transport regulates branching patterns in flowering plants, this is not so in Physcomitrella, where bi-directional transport is required to generate realistic branching patterns. Experiments with callose synthesis inhibitors suggest plasmodesmal connectivity as a potential mechanism for transport.

  9. The super-ordinate nature of the psychopathy checklist-revised.

    Science.gov (United States)

    Neumann, Craig S; Hare, Robert D; Newman, Joseph P

    2007-04-01

    Psychopathy, while perhaps the earliest and most recognized personality disorder, is the subject of intense debate about its nature and measurement. The most recent proposal on its structural nature suggests that it is a multifaceted construct, made up of at least four dimensions reflecting Interpersonal, Affective, Lifestyle, and Antisocial anomalies (Hare & Neumann, 2005, 2006). These dimensions are significantly interrelated, suggesting that they are indicators for a super-ordinate factor. The nature of this higher-order factor may reflect the unifying feature which comprehensively defines the disorder. To examine this super-factor, the current study used several very large data sets of male (N = 4865) and female (N = 1099) offenders, and forensic psychiatric patients (N = 965), who were assessed with the Psychopathy Checklist-Revised (PCL-R; Hare, 2003). Structural equation modeling results indicated that the four first-order factor dimensions could be explained by a single second-order cohesive super-factor.

  10. Generation of a computer library for discrete ordinates quadrature sets

    International Nuclear Information System (INIS)

    Jenal, J.P.; Erickson, P.J.; Rhoades, W.A.; Simpson, D.B.; Williams, M.L.

    1977-10-01

    Although various discrete-ordinates quadrature sets are in general use, there exists a need for a standard collection supported by documentation of their origin and derivation. This report attempts to provide this documentation for most of the commonly used sets. Instructions for using DOQDP--the computer code used to generate these quadratures--is provided. A library (in standard interface format) containing many of the quadratures was generated and is documented in this report. Finally, a listing of the fully symmetric, half-symmetric, and several biased sets is provided for XY, RZ, and R THETA geometries. Part I of the report describes the DOQDP code and the generation of S2-S16 fully symmetric quadratures. Part II describes the generation of S4-S10 half-symmetric and several biased sets, as well as a discussion of the quadrature library. 2 figures, 1 table

  11. A discrete ordinate response matrix method for massively parallel computers

    International Nuclear Information System (INIS)

    Hanebutte, U.R.; Lewis, E.E.

    1991-01-01

    A discrete ordinate response matrix method is formulated for the solution of neutron transport problems on massively parallel computers. The response matrix formulation eliminates iteration on the scattering source. The nodal matrices which result from the diamond-differenced equations are utilized in a factored form which minimizes memory requirements and significantly reduces the required number of algorithm utilizes massive parallelism by assigning each spatial node to a processor. The algorithm is accelerated effectively by a synthetic method in which the low-order diffusion equations are also solved by massively parallel red/black iterations. The method has been implemented on a 16k Connection Machine-2, and S 8 and S 16 solutions have been obtained for fixed-source benchmark problems in X--Y geometry

  12. Particular solution of the discrete-ordinate method.

    Science.gov (United States)

    Qin, Yi; Box, Michael A; Jupp, David L

    2004-06-20

    We present two methods that can be used to derive the particular solution of the discrete-ordinate method (DOM) for an arbitrary source in a plane-parallel atmosphere, which allows us to solve the transfer equation 12-18% faster in the case of a single beam source and is even faster for the atmosphere thermal emission source. We also remove the divide by zero problem that occurs when a beam source coincides with a Gaussian quadrature point. In our implementation, solution for multiple sources can be obtained simultaneously. For each extra source, it costs only 1.3-3.6% CPU time required for a full solution. The GDOM code that we developed previously has been revised to integrate with the DOM. Therefore we are now able to compute the Green's function and DOM solutions simultaneously.

  13. Parallel ray tracing for one-dimensional discrete ordinate computations

    International Nuclear Information System (INIS)

    Jarvis, R.D.; Nelson, P.

    1996-01-01

    The ray-tracing sweep in discrete-ordinates, spatially discrete numerical approximation methods applied to the linear, steady-state, plane-parallel, mono-energetic, azimuthally symmetric, neutral-particle transport equation can be reduced to a parallel prefix computation. In so doing, the often severe penalty in convergence rate of the source iteration, suffered by most current parallel algorithms using spatial domain decomposition, can be avoided while attaining parallelism in the spatial domain to whatever extent desired. In addition, the reduction implies parallel algorithm complexity limits for the ray-tracing sweep. The reduction applies to all closed, linear, one-cell functional (CLOF) spatial approximation methods, which encompasses most in current popular use. Scalability test results of an implementation of the algorithm on a 64-node nCube-2S hypercube-connected, message-passing, multi-computer are described. (author)

  14. The adaptive collision source method for discrete ordinates radiation transport

    International Nuclear Information System (INIS)

    Walters, William J.; Haghighat, Alireza

    2017-01-01

    Highlights: • A new adaptive quadrature method to solve the discrete ordinates transport equation. • The adaptive collision source (ACS) method splits the flux into n’th collided components. • Uncollided flux requires high quadrature; this is lowered with number of collisions. • ACS automatically applies appropriate quadrature order each collided component. • The adaptive quadrature is 1.5–4 times more efficient than uniform quadrature. - Abstract: A novel collision source method has been developed to solve the Linear Boltzmann Equation (LBE) more efficiently by adaptation of the angular quadrature order. The angular adaptation method is unique in that the flux from each scattering source iteration is obtained, with potentially a different quadrature order used for each. Traditionally, the flux from every iteration is combined, with the same quadrature applied to the combined flux. Since the scattering process tends to distribute the radiation more evenly over angles (i.e., make it more isotropic), the quadrature requirements generally decrease with each iteration. This method allows for an optimal use of processing power, by using a high order quadrature for the first iterations that need it, before shifting to lower order quadratures for the remaining iterations. This is essentially an extension of the first collision source method, and is referred to as the adaptive collision source (ACS) method. The ACS methodology has been implemented in the 3-D, parallel, multigroup discrete ordinates code TITAN. This code was tested on a several simple and complex fixed-source problems. The ACS implementation in TITAN has shown a reduction in computation time by a factor of 1.5–4 on the fixed-source test problems, for the same desired level of accuracy, as compared to the standard TITAN code.

  15. Co-ordinated research programme applications of stable isotope tracers in human nutrition research

    International Nuclear Information System (INIS)

    1992-01-01

    The objective of this Co-ordinated Research Programme is to help establish competence in the use of stable isotope techniques, particularly in developing countries. This report summarizes the discussions that took, place during the Second Research Co-ordination Meeting, held in Bangalore in November 1990. Working papers presented by the participants are included as annexes. Refs, figs and tabs

  16. 75 FR 41518 - Match-E-Be-Nash-She-Wish (Gun Lake) Tribe Liquor Control Ordinance

    Science.gov (United States)

    2010-07-16

    ... DEPARTMENT OF THE INTERIOR Bureau of Indian Affairs Match-E-Be-Nash-She-Wish (Gun Lake) Tribe... publishes the Secretary's certification of the Match-E-Be-Nash-She-Wish Band of Pottawatomi Indians (Gun.... The Tribal Council of the Gun Lake Tribe Liquor Control Ordinance adopted this Liquor Ordinance on...

  17. Ordinance of the Federal Department of the Interior on radiation protection in nuclear research institutes

    International Nuclear Information System (INIS)

    1969-09-01

    This Ordinance was made in implementation of Section 116 of the Ordinance of 19 April 1963 on radiation protection. It applies to institutes undertaking nuclear research which are equipped with apparatus emitting ionizing radiation, excluding nuclear installations. It defines the radiation protection measures to be applied in such institutes. (NEA) [fr

  18. First IAEA research co-ordination meeting on 'Tritium inventory in fusion reactors'. Summary report

    International Nuclear Information System (INIS)

    Clark, R.E.H.

    2003-02-01

    The proceedings and conclusions of the first Research Co-ordination Meeting on 'Tritium Inventory in Fusion Reactors', held on November 4-6, 2002 at the IAEA Headquarters in Vienna are briefly described. This report includes a summary of the presentations made by the meeting participants and the specific goals set by the participants of the Co-ordinated Research Project (CRP). (author)

  19. Dominant supply chain co-ordination strategies in the Dutch aerospace industry

    NARCIS (Netherlands)

    Voordijk, Johannes T.; Meijboom, Bert

    2005-01-01

    Purpose – Firms in the aerospace industry face considerable pressure to improve co-ordination in their supply chains. The major question of the present study is what supply chain co-ordination strategies are dominant in the Dutch aerospace industry given the market environment of this industry?

  20. Ordinance of 18 January 1984 on definitions and licences in the atomic energy field

    International Nuclear Information System (INIS)

    1984-01-01

    This Ordinance (RS 732.11) repeals the 1978 Ordinance on definitions and licences in the atomic energy field with the exception of Annexes 2 and 3 and concerns in particular, the licensing procedure for atomic installations. It also regulates the export, import and transit of nuclear materials and equipment. (NEA) [fr

  1. Optimization of Saccharification Conditions of Lignocellulosic Biomass under Alkaline Pre-Treatment and Enzymatic Hydrolysis

    Directory of Open Access Journals (Sweden)

    Rafał Łukajtis

    2018-04-01

    Full Text Available Pre-treatment is a significant step in the production of second-generation biofuels from waste lignocellulosic materials. Obtaining biofuels as a result of fermentation processes requires appropriate pre-treatment conditions ensuring the highest possible degree of saccharification of the feed material. An influence of the following process parameters were investigated for alkaline pre-treatment of Salix viminalis L.: catalyst concentration (NaOH, temperature, pre-treatment time and granulation. For this purpose, experiments were carried out in accordance to the Box-Behnken design for four factors. In the saccharification process of the pre-treated biomass, cellulolytic enzymes immobilized on diatomaceous earth were used. Based on the obtained results, a mathematical model for the optimal conditions of alkaline pre-treatment prediction is proposed. The optimal conditions of alkaline pre-treatment are established as follows: granulation 0.75 mm, catalyst concentration 7%, pre-treatment time 6 h and temperature 65 °C if the saccharification efficiency and cost analysis are considered. An influence of the optimized pre-treatment on both the chemical composition and structural changes for six various lignocellulosic materials (energetic willow, energetic poplar, beech, triticale, meadow grass, corncobs was investigated. SEM images of raw and pre-treated biomass samples are included in order to follow the changes in the biomass structure during hydrolysis.

  2. No toy for you! The healthy food incentives ordinance: paternalism or consumer protection?

    Science.gov (United States)

    Etow, Alexis M

    2012-01-01

    The newest approach to discouraging children's unhealthy eating habits, amidst increasing rates of childhood obesity and other diet-related diseases, seeks to ban something that is not even edible. In 2010, San Francisco enacted the Healthy Food Incentives Ordinance, which prohibits toys in kids' meals if the meals do not meet certain nutritional requirements. Notwithstanding the Ordinance's impact on interstate commerce or potential infringement on companies' commercial speech rights and on parents' rights to determine what their children eat, this Comment argues that the Ordinance does not violate the dormant Commerce Clause, the First Amendment, or substantive due process. The irony is that although the Ordinance likely avoids the constitutional hurdles that hindered earlier measures aimed at childhood obesity, it intrudes on civil liberties more than its predecessors. This Comment analyzes the legality of the Healthy Food Incentives Ordinance to understand its implications on subsequent legislation aimed at combating childhood obesity and on the progression of public health law.

  3. Two-dimensional discrete ordinates photon transport calculations for brachytherapy dosimetry applications

    International Nuclear Information System (INIS)

    Daskalov, G.M.; Baker, R.S.; Little, R.C.; Rogers, D.W.O.; Williamson, J.F.

    2000-01-01

    The DANTSYS discrete ordinates computer code system is applied to quantitative estimation of water kerma rate distributions in the vicinity of discrete photon sources with energies in the 20- to 800-keV range in two-dimensional cylindrical r-z geometry. Unencapsulated sources immersed in cylindrical water phantoms of 40-cm diameter and 40-cm height are modeled in either homogeneous phantoms or shielded by Ti, Fe, and Pb filters with thicknesses of 1 and 2 mean free paths. The obtained dose results are compared with corresponding photon Monte Carlo simulations. A 210-group photon cross-section library for applications in this energy range is developed and applied, together with a general-purpose 42-group library developed at Los Alamos National Laboratory, for DANTSYS calculations. The accuracy of DANTSYS with the 42-group library relative to Monte Carlo exhibits large pointwise fluctuations from -42 to +84%. The major cause for the observed discrepancies is determined to be the inadequacy of the weighting function used for the 42-group library derivation. DANTSYS simulations with a finer 210-group library show excellent accuracy on and off the source transverse plane relative to Monte Carlo kerma calculations, varying from minus4.9 to 3.7%. The P 3 Legendre polynomial expansion of the angular scattering function is shown to be sufficient for accurate calculations. The results demonstrate that DANTSYS is capable of calculating photon doses in very good agreement with Monte Carlo and that the multigroup cross-section library and efficient techniques for mitigation of ray effects are critical for accurate discrete ordinates implementation

  4. Rheological evaluation of pretreated cladding removal waste

    International Nuclear Information System (INIS)

    McCarthy, D.; Chan, M.K.C.; Lokken, R.O.

    1986-01-01

    Cladding removal waste (CRW) contains concentrations of transuranic (TRU) elements in the 80 to 350 nCi/g range. This waste will require pretreatment before it can be disposed of as glass or grout at Hanford. The CRW will be pretreated with a rare earth strike and solids removal by centrifugation to segregate the TRU fraction from the non-TRU fraction of the waste. The centrifuge centrate will be neutralized with sodium hydroxide. This neutralized cladding removal waste (NCRW) is expected to be suitable for grouting. The TRU solids removed by centrifugation will be vitrified. The goal of the Rheological Evaluation of Pretreated Cladding Removal Waste Program was to evaluate those rheological and transport properties critical to assuring successful handling of the NCRW and TRU solids streams and to demonstrate transfers in a semi-prototypic pumping environment. This goal was achieved by a combination of laboratory and pilot-scale evaluations. The results obtained during these evaluations were correlated with classical rheological models and scaled-up to predict the performance that is likely to occur in the full-scale system. The Program used simulated NCRW and TRU solid slurries. Rockwell Hanford Operations (Rockwell) provided 150 gallons of simulated CRW and 5 gallons of simulated TRU solid slurry. The simulated CRW was neutralized by Pacific Northwest Laboratory (PNL). The physical and rheological properties of the NCRW and TRU solid slurries were evaluated in the laboratory. The properties displayed by NCRW allowed it to be classified as a pseudoplastic or yield-pseudoplastic non-Newtonian fluid. The TRU solids slurry contained very few solids. This slurry exhibited the properties associated with a pseudoplastic non-Newtonian fluid

  5. GGVS. Ordinance on road transport of hazardous materials, including the European agreement on international road transport of hazardous materials (ADR), in their wording. Annexes A and B. Ordinances regarding exceptions from GGVS and from the ordinance on rail transport of hazardous materials, GGVE. Reasons. Selected guidelines. List of materials. 6. rev. and enlarged ed.

    International Nuclear Information System (INIS)

    Ridder, K.

    1990-01-01

    The brochure contains the following texts: (1) Ordinance on road transport of hazardous materials (GGVS), including the European agreement on international road transport of hazardous materials (ADR), as of 1990: Skeleton ordinance, annexes A and B, reasons given for the first version, and for the first amendment in 1988, execution guidelines - RS 002 (guidelines for executing the ordinance on road transport of hazardous materials, with catalogue of penalties), guidelines for drawing up written instructions for the event of accidents - RS 006, guiding principles for the training of vehicle conductors; (2) ordinance regarding exceptions from the ordinance on road transport of hazardous materials; (3) ordinance regarding exceptions from the ordinance on rail transport of hazardous materials; (4) selected guidelines: Technical guidelines TR IBC K 001, TRS 003, TRS 004, TRS 005, TRS 006; (5) listing of materials and objects governed by the ordinance on hazardous materials transport; (6) catalogue of penalties relative to road transport of hazardous materials. (orig./HP) [de

  6. Pretreatment Solution for Water Recovery Systems

    Science.gov (United States)

    Muirhead, Dean (Inventor)

    2018-01-01

    Chemical pretreatments are used to produce usable water by treating a water source with a chemical pretreatment that contains a hexavalent chromium and an acid to generate a treated water source, wherein the concentration of sulfate compounds in the acid is negligible, and wherein the treated water source remains substantially free of precipitates after the addition of the chemical pretreatment. Other methods include reducing the pH in urine to be distilled for potable water extraction by pretreating the urine before distillation with a pretreatment solution comprising one or more acid sources selected from a group consisting of phosphoric acid, hydrochloric acid, and nitric acid, wherein the urine remains substantially precipitate free after the addition of the pretreatment solution. Another method described comprises a process for reducing precipitation in urine to be processed for water extraction by mixing the urine with a pretreatment solution comprising hexavalent chromium compound and phosphoric acid.

  7. About local fractional three-dimensional compressible Navier-Stokes equations in Cantor-type cylindrical co-ordinate system

    Directory of Open Access Journals (Sweden)

    Gao Guo-Ping

    2016-01-01

    Full Text Available In this article, we investigate the local fractional 3-D compressible Navier-Stokes equation via local fractional derivative. We use the Cantor-type cylindrical co-ordinate method to transfer 3-D compressible Navier-Stokes equation from the Cantorian co-ordinate system to the Cantor-type cylindrical co-ordinate system.

  8. Pre-treatment growth and IGF-I deficiency as main predictors of response to growth hormone therapy in neural models

    Directory of Open Access Journals (Sweden)

    Urszula Smyczyn´ska

    2018-01-01

    Full Text Available Mathematical models have been applied in prediction of growth hormone treatment effectiveness in children since the end of 1990s. Usually they were multiple linear regression models; however, there are also examples derived by empirical non-linear methods. Proposed solution consists in application of machine learning technique – artificial neural networks – to analyse this problem. This new methodology, contrary to previous ones, allows detection of both linear and non-linear dependencies without assuming their character a priori. The aims of this work included: development of models predicting separately growth during 1st year of treatment and final height as well as identification of important predictors and in-depth analysis of their influence on treatment’s effectiveness. The models were derived on the basis of clinical data of 272 patients treated for at least 1 year, 133 of whom have already attained final height. Starting from models containing 17 and 20 potential predictors, respectively for 1st year and final height model, we were able to reduce their number to 9 and 10. Basing on the final models, IGF-I concentration and earlier growth were indicated as belonging to most important predictors of response to GH therapy, while results of GH secretion tests were automatically excluded as insignificant. Moreover, majority of the dependencies were observed to be non-linear, thus using neural networks seems to be reasonable approach despite it being more complex than previously applied methods.

  9. Ohmic heating pretreatment of algal slurry for production of biodiesel.

    Science.gov (United States)

    Yodsuwan, Natthawut; Kamonpatana, Pitiya; Chisti, Yusuf; Sirisansaneeyakul, Sarote

    2018-02-10

    Suspensions of the model microalga Chlorella sp. TISTR 8990 were pretreated by ohmic heating to facilitate release of lipids from the cells in subsequent extraction and lipase-mediated transesterification to biodiesel. After ohmic pretreatment, the moist biomass was suspended in a system of water, hexane, methanol and immobilized lipase for extraction of lipids and simultaneous conversion to biodiesel. The ohmic pretreatment was optimized using an experimental design based on Taguchi method to provide treated biomass that maximized the biodiesel yield in subsequent extraction-transesterification operation. The experimental factors were the frequency of electric current (5-10 5  Hz), the processing temperature (50-70 °C), the algal biomass concentration in the slurry (algal fresh weight to water mass ratio of 1-3) and the incubation time (1-3 min). Extraction-transesterification of the pretreated biomass was carried out at 40 °C for 24 h using a reaction systems of a fixed composition (i.e. biomass, hexane, methanol, water and immobilized enzyme). Compared to control (i.e. untreated biomass), the ohmic pretreatment under optimal conditions (5 Hz current frequency, 70 °C, 1:2 mass ratio of biomass to water, incubation time of 2-min) increased the rate of subsequent transesterification by nearly 2-fold. Copyright © 2017 Elsevier B.V. All rights reserved.

  10. The German Radiation Protection Ordinance (StrlSchV). 3. ed.

    International Nuclear Information System (INIS)

    Hinrichs, O.

    1992-01-01

    The German Radiation Protection Ordinance constitutes the central statutory instrument containing the main protective provisions for all fields of application of radioactive materials and ionizing radiation, with the exception of the field covered by the X-ray Ordinance. The current text of the Ordinance is that promulgated on 30.06.1989 with the subsequent amendments, as last amended through the Unification Treaty (Einigungsvertrag) of 23.09.1990. The Radiation Protection Ordinance was adopted on the basis of the German Nuclear Energy Act (Atomgesetz), which contains, inter alia, the necessary empowerments to issue statutory ordinances. Further fields containing relevant protective provisions are, above all, the law of dangerous substances (which concerns the transport of radioactive materials), the law of pharmaceutical products and the law of foodstuffs. The whole regulatory package is a part of EC and Euratom law. The limit values of the Euratom Directives were transposed into the Radiation Protection Ordinance. In order to reduce the bulk of the Ordinance, the legislator has only included the limit values for the most important radionuclides, and has made provision for the separate promulgation of the other limit values. In order to enhance the practical use of the book, the provisions governing the radiation pass, which are regulated in a separate administrative instruction, are also reproduced. (orig./HSCH) [de

  11. Assessment of Shock Pretreatment of Corn Stover Using the Carboxylate Platform.

    Science.gov (United States)

    Darvekar, Pratik; Holtzapple, Mark T

    2016-03-01

    Corn stover was pretreated with lime and shock, a mechanical process that uses a shockwave to alter the biomass structure. Two pretreatments (lime-only and lime + shock) were evaluated using enzymatic hydrolysis, batch mixed-culture fermentations, and continuous countercurrent mixed-culture fermentation. In a 120-h enzymatic hydrolysis, shock pretreatment increased the glucan digestibility of submerged lime pretreatment (SLP) corn stover by 3.5 % and oxidative lime pretreatment (OLP) corn stover by 2.5 %. The continuum particle distribution model (CPDM) was used to simulate a four-stage continuous countercurrent mixed-culture fermentation using empirical rate models obtained from simple batch experiments. The CPDM model determined that lime + shock pretreatment increased the total carboxylic acids yield by 28.5 % over lime-only pretreatment in a countercurrent fermentation with a volatile solids loading rate (VSLR) of 12 g/(L/day) and liquid retention time (LRT) of 30 days. In a semi-continuous countercurrent fermentation performed in the laboratory for 112 days with a VSLR of 1.875 g/(L day) and LRT of 16 days, lime + shock pretreatment increased the total carboxylic acid yield by 14.8 %. The experimental results matched closely with CPDM model predictions (4.05 % error).

  12. Co-ordinated action between youth-care and sports: facilitators and barriers.

    Science.gov (United States)

    Hermens, Niels; de Langen, Lisanne; Verkooijen, Kirsten T; Koelen, Maria A

    2017-07-01

    In the Netherlands, youth-care organisations and community sports clubs are collaborating to increase socially vulnerable youths' participation in sport. This is rooted in the idea that sports clubs are settings for youth development. As not much is known about co-ordinated action involving professional care organisations and community sports clubs, this study aims to generate insight into facilitators of and barriers to successful co-ordinated action between these two organisations. A cross-sectional study was conducted using in-depth semi-structured qualitative interview data. In total, 23 interviews were held at five locations where co-ordinated action between youth-care and sports takes place. Interviewees were youth-care workers, representatives from community sports clubs, and Care Sport Connectors who were assigned to encourage and manage the co-ordinated action. Using inductive coding procedures, this study shows that existing and good relationships, a boundary spanner, care workers' attitudes, knowledge and competences of the participants, organisational policies and ambitions, and some elements external to the co-ordinated action were reported to be facilitators or barriers. In addition, the participants reported that the different facilitators and barriers influenced the success of the co-ordinated action at different stages of the co-ordinated action. Future research is recommended to further explore the role of boundary spanners in co-ordinated action involving social care organisations and community sports clubs, and to identify what external elements (e.g. events, processes, national policies) are turning points in the formation, implementation and continuation of such co-ordinated action. © 2017 John Wiley & Sons Ltd.

  13. ASOP, Shield Calculation, 1-D, Discrete Ordinates Transport

    International Nuclear Information System (INIS)

    1993-01-01

    1 - Nature of physical problem solved: ASOP is a shield optimization calculational system based on the one-dimensional discrete ordinates transport program ANISN. It has been used to design optimum shields for space applications of SNAP zirconium-hydride-uranium- fueled reactors and uranium-oxide fueled thermionic reactors and to design beam stops for the ORELA facility. 2 - Method of solution: ASOP generates coefficients of linear equations describing the logarithm of the dose and dose-weight derivatives as functions of position from data obtained in an automated sequence of ANISN calculations. With the dose constrained to a design value and all dose-weight derivatives required to be equal, the linear equations may be solved for a new set of shield dimensions. Since changes in the shield dimensions may cause the linear functions to change, the entire procedure is repeated until convergence is obtained. The detailed calculations of the radiation transport through shield configurations for every step in the procedure distinguish ASOP from other shield optimization computer code systems which rely on multiple component sources and attenuation coefficients to describe the transport. 3 - Restrictions on the complexity of the problem: Problem size is limited only by machine size

  14. Discrete ordinates quadrature schemes for multidimensional radiative transfer

    Science.gov (United States)

    Koch, R.; Krebs, W.; Wittig, S.; Viskanta, R.

    1995-04-01

    The fundamental problem of applying the method of discrete ordinates to radiative transfer predictions is the selection of the discrete directions and their associated weights. Both the accuracy of the solution and the computational effort depend on the angular discretization. This paper provides a sound mathematical methodology for the derivation of angular quadratures. By applying the collocation principle, the errors introduced by a quadrature are analyzed and the constituting equations of angular quadratures are identified. Special emphasis is placed on the rotational invariance of the qudrature schemes. Multidimensional radiative transfer in participating media with isotropic and anisotropic scattering is accounted for thoughout the analysis. A major goal of the present study is the construction of a new principle for multidimensional angular quadratures which is essentially a generalization of the principles employed for the well-known S(sub n) quadratures. The new construction principle has two major advantages. First, it enables a very flexible tailoring of quadratures according to the actual requirements. Second, compared to the S(sub n) quadratures, the new types of quadratures provide a higher accuracy while using the same number of nodal points.

  15. [The ordinal localization of multiple mono-type carpal bones].

    Science.gov (United States)

    Zviagin, V N; Zamiatina, A O

    2003-01-01

    The case study was based on the osteologic collection of the chair for anthropology, State Moscow University, including the male carpal bones (67) and female carpal bones (13), aged above 18 to 20. Four measurements were made according to Martin's scheme for metacarpal bones and finger phalanxes. A diagnostic method was worked out on the bases of the discriminative analysis, with such method enabling the remodeling of the ordinal localization of metacarpal bones as well as of main, medium and distal phalanxes. The maximally accurate classification was ensured for metacarpal bones, ranging from 81.5% to 100%; and the minimally accurate one was achieved for distal phalanxes, ranging from 20% to 95%. The discriminative analysis results were checked for distal phalanxes by Neklyudov's series (male--100, female--85); they were described according to 7 sizes. However, an attempt to enhance the accuracy of the classification of these phalanxes failed. The offered method should be applied in combination with the traditional anatomic-and-morphological method; besides, if possible, it is necessary to check the congruence of joint surfaces in the metacarpal interphalangeal joints.

  16. Parallel discrete ordinates methods in the SCEPTRE project

    International Nuclear Information System (INIS)

    Pautz, S.; Bohnhoff, B.; Drumm, C.; Fan, W.

    2009-01-01

    Although the transport of photons and electrons/positrons can be described by the same Boltzmann transport equation, the cross sections are very different, resulting in very different iterative convergence properties for the two particle types. The SCEPTRE project contains a suite of deterministic codes for solving the linear steady-state Boltzmann transport equation, including two very different solution algorithms: a sweeps-based approach for solving the first-order transport equation that is efficient for photon transport, and a conjugate-gradient algorithm for solving the second-order transport equation that is efficient for electron/positron transport. These two solution algorithms are coupled through a common set of interfaces to handle the finite element approximation in space, the discrete-ordinates method in angle, the scattering source terms, input parsing, pre- and post-processing capabilities. We evaluate the two solution algorithms by comparing the run times for photon- and electron-transport problems, investigating parallel performance and effects from finite-element basis function types, preconditioning, and scaling with angular quadrature order and Legendre cross section expansion order. (authors)

  17. Eurotrac: a co-ordinated project for applied tropospheric research

    Energy Technology Data Exchange (ETDEWEB)

    Borrell, P. [EUROTRAC International Scientific Secretariat, Garmisch-Partenkirchen (Germany)

    1995-12-31

    It was with the realisation that the scientific problems associated with regional air pollution could only be solved within the framework of an international interdisciplinary approach that in 1985 EUROTRAC, the European co-ordinated research project, was formed. Such an approach provides the scientific consensus necessary for the acceptance of regional air-pollution abatement measures by the countries affected. EUROTRAC is a EUREKA environmental project, studying the transport and chemical transformation of trace substances and pollutants in the troposphere. Three goals were specified the outset: (1) to increase the basic knowledge in atmospheric science, (2) to promote the technological development of sensitive, specific and fast response instruments for environmental research and development, and (3) to improve the scientific basis for taking future political decisions on environmental management in the European countries. Thus EUROTRAC was founded as a scientific project but had the specific intention that its results should be utilised in the formulation of policy. This presentation reviews the progress made towards each of the three goals and also indicates the proposed direction which a follow-on project is likely to take when EUROTRAC finishes at the end of 1995. (author)

  18. Co-ordinate activation of lipogenic enzymes in hepatocellular carcinoma.

    Science.gov (United States)

    Yahagi, Naoya; Shimano, Hitoshi; Hasegawa, Kiyoshi; Ohashi, Kenichi; Matsuzaka, Takashi; Najima, Yuho; Sekiya, Motohiro; Tomita, Sachiko; Okazaki, Hiroaki; Tamura, Yoshiaki; Iizuka, Yoko; Ohashi, Ken; Nagai, Ryozo; Ishibashi, Shun; Kadowaki, Takashi; Makuuchi, Masatoshi; Ohnishi, Shin; Osuga, Jun-ichi; Yamada, Nobuhiro

    2005-06-01

    Hepatocellular carcinoma is a very common neoplastic disease in countries where hepatitis viruses B and/or C are prevalent. Small hepatocellular carcinoma lesions detected by ultrasonography at an early stage are often hyperechoic because they are composed of well-differentiated cancer cells that are rich in triglyceride droplets. The triglyceride content of hepatocytes depends in part on the rate of lipogenesis. Key lipogenic enzymes, such as fatty acid synthase, are co-ordinately regulated at the transcriptional level. We therefore examined the mRNA expression of lipogenic enzymes in human hepatocellular carcinoma samples from 10 patients who had undergone surgical resection. All of the samples exhibited marked elevation of expression of mRNA for lipogenic enzymes, such as fatty acid synthase, acetyl-CoA carboxylase and ATP citrate lyase, compared with surrounding non-cancerous liver tissue. In contrast, the changes in mRNA expression of SREBP-1, a transcription factor that regulates a battery of lipogenic enzymes, did not show a consistent trend. In some cases where SREBP-1 was elevated, the main contributing isoform was SREBP-1c rather than SREBP-1a. Thus, lipogenic enzymes are markedly induced in hepatocellular carcinomas, and in some cases SREBP-1c is involved in this activation.

  19. How protein kinases co-ordinate mitosis in animal cells.

    Science.gov (United States)

    Ma, Hoi Tang; Poon, Randy Y C

    2011-04-01

    Mitosis is associated with profound changes in cell physiology and a spectacular surge in protein phosphorylation. To accomplish these, a remarkably large portion of the kinome is involved in the process. In the present review, we will focus on classic mitotic kinases, such as cyclin-dependent kinases, Polo-like kinases and Aurora kinases, as well as more recently characterized players such as NIMA (never in mitosis in Aspergillus nidulans)-related kinases, Greatwall and Haspin. Together, these kinases co-ordinate the proper timing and fidelity of processes including centrosomal functions, spindle assembly and microtubule-kinetochore attachment, as well as sister chromatid separation and cytokinesis. A recurrent theme of the mitotic kinase network is the prevalence of elaborated feedback loops that ensure bistable conditions. Sequential phosphorylation and priming phosphorylation on substrates are also frequently employed. Another important concept is the role of scaffolds, such as centrosomes for protein kinases during mitosis. Elucidating the entire repertoire of mitotic kinases, their functions, regulation and interactions is critical for our understanding of normal cell growth and in diseases such as cancers.

  20. Efficient iris texture analysis method based on Gabor ordinal measures

    Science.gov (United States)

    Tajouri, Imen; Aydi, Walid; Ghorbel, Ahmed; Masmoudi, Nouri

    2017-07-01

    With the remarkably increasing interest directed to the security dimension, the iris recognition process is considered to stand as one of the most versatile technique critically useful for the biometric identification and authentication process. This is mainly due to every individual's unique iris texture. A modestly conceived efficient approach relevant to the feature extraction process is proposed. In the first place, iris zigzag "collarette" is extracted from the rest of the image by means of the circular Hough transform, as it includes the most significant regions lying in the iris texture. In the second place, the linear Hough transform is used for the eyelids' detection purpose while the median filter is applied for the eyelashes' removal. Then, a special technique combining the richness of Gabor features and the compactness of ordinal measures is implemented for the feature extraction process, so that a discriminative feature representation for every individual can be achieved. Subsequently, the modified Hamming distance is used for the matching process. Indeed, the advanced procedure turns out to be reliable, as compared to some of the state-of-the-art approaches, with a recognition rate of 99.98%, 98.12%, and 95.02% on CASIAV1.0, CASIAV3.0, and IIT Delhi V1 iris databases, respectively.

  1. Sleep behaviour in children with developmental co-ordination disorder.

    Science.gov (United States)

    Barnett, A L; Wiggs, L

    2012-05-01

    Children with developmental co-ordination disorder (DCD) experience significant difficulty in the performance of everyday movement skills in the absence of obvious neurological, sensory or intellectual impairment. They often underachieve academically and have higher rates of anxiety than their typically developing peers. Such factors are known to be associated with sleep problems in other clinical populations but the sleep patterns of children with DCD have not been examined. Information about the frequency and nature of sleep problems in DCD will aid our understanding of this developmental disorder. It may also be clinically helpful, alerting clinicians to potential difficulties so that these can be identified early and appropriate support offered. To examine sleep behaviour of children with DCD compared with typically developing control children. Two groups of 16 boys aged 8 to 12 years (M = 10.28, SD = 1.28) participated: (1) the DCD group had Movement ABC-2 Checklist scores below the 5th percentile; (2) an age-matched control group of typically developing children had Movement ABC-2 Checklist scores above the 15th percentile. Parents of children from both groups completed the Children's Sleep Habits Questionnaire. The total sleep disturbance score was significantly higher for children with DCD compared with the control group (U= 24, P sleep onset delay, sleep duration, night wakings and sleep-disordered breathing. These preliminary results suggest that sleep patterns of children with DCD may be of clinical relevance and are worthy of further investigation. © 2011 Blackwell Publishing Ltd.

  2. Human Action Recognition Using Ordinal Measure of Accumulated Motion

    Directory of Open Access Journals (Sweden)

    Kim Wonjun

    2010-01-01

    Full Text Available This paper presents a method for recognizing human actions from a single query action video. We propose an action recognition scheme based on the ordinal measure of accumulated motion, which is robust to variations of appearances. To this end, we first define the accumulated motion image (AMI using image differences. Then the AMI of the query action video is resized to a subimage by intensity averaging and a rank matrix is generated by ordering the sample values in the sub-image. By computing the distances from the rank matrix of the query action video to the rank matrices of all local windows in the target video, local windows close to the query action are detected as candidates. To find the best match among the candidates, their energy histograms, which are obtained by projecting AMI values in horizontal and vertical directions, respectively, are compared with those of the query action video. The proposed method does not require any preprocessing task such as learning and segmentation. To justify the efficiency and robustness of our approach, the experiments are conducted on various datasets.

  3. Co-ordinated research programme on applications of stable isotope tracers in human nutrition research

    International Nuclear Information System (INIS)

    1992-01-01

    This document provides a very brief report on the final Research Co-ordination Meeting of this Co-ordinated Research Project (CRP): the final report on the CRP will be published by the IAEA in the IAEA-TECDOC series. The present document contains a detailed proposal for a new Co-ordinated Research Programme on ''Stable Isotope Tracer Techniques for Studies on Protein-Energy Interactions'', and a brief series of notes on stable isotopic methods for investigating protein and amino-acid metabolism in man. Refs

  4. Nuclear based technologies for estimating microbial protein supply in ruminant livestock. Proceedings of the second research co-ordination meeting of a co-ordinated research project (phase 1)

    International Nuclear Information System (INIS)

    1999-06-01

    The Joint FAO/IAEA Division of Nuclear Techniques in Food and Agriculture through its Co-ordinated Research Projects (CRPs), has been assisting national agricultural research systems in Member States to develop and apply nuclear and related techniques for improving livestock productivity. The programmes have focused on animal nutrition, animal reproduction and more recently on animal nutrition/reproduction interactions with emphasis on smallholder farming systems. The measurement of microbial protein supply to ruminant livestock has been an important area of research in ruminant nutrition. An estimate of microbial protein contribution to the intestinal protein flow is important for estimating the protein requirement of ruminant animals. Understanding the process of microbial protein synthesis has been difficult however, and due to the lack of simple and accurate methods for measuring microbial protein production in vivo, the methods used are based on complex microbial markers which require surgically prepared animals. As a result of a consultants meeting held in May 1995 to advise the Joint FAO/IAEA Division on the feasibility of using nuclear and related techniques for the development and validation of techniques for measuring microbial protein supply in ruminant animals, an FAO/IAEA Co-ordinated Research Project on Development, Standardization and Validation of Nuclear Based Technologies for Measuring Microbial Protein Supply in Ruminant Livestock for Improving Productivity was initiated in 1996, with a view to validating and adapting this technology for use in developing countries. To assist scientists participating in the CRP, a laboratory manual containing experimental protocols and methodologies for standardization and validation of the urine purine derivative technique and the development of models to suit local conditions, was published as IAEA-TECDOC-945. The present publication contains the final reports from participants in Phase 1 of the project

  5. Method for pretreating lignocellulosic biomass

    Science.gov (United States)

    Kuzhiyil, Najeeb M.; Brown, Robert C.; Dalluge, Dustin Lee

    2015-08-18

    The present invention relates to a method for pretreating lignocellulosic biomass containing alkali and/or alkaline earth metal (AAEM). The method comprises providing a lignocellulosic biomass containing AAEM; determining the amount of the AAEM present in the lignocellulosic biomass; identifying, based on said determining, the amount of a mineral acid sufficient to completely convert the AAEM in the lignocellulosic biomass to thermally-stable, catalytically-inert salts; and treating the lignocellulosic biomass with the identified amount of the mineral acid, wherein the treated lignocellulosic biomass contains thermally-stable, catalytically inert AAEM salts.

  6. Ordination techniques for analysing response of biological communities to toxic stress in experimental ecosystems.

    NARCIS (Netherlands)

    Wijngaarden, van R.P.A.; Brink, van den P.J.; Oude Voshaar, J.H.; Leeuwangh, P.

    1995-01-01

    The ordination techniques Principal Component Analysis (PCA) and Redundancy Analysis (RDA) are considered to be useful tools for evaluating community responses in experimental ecotoxicology. Concepts and interpretation of these techniques are summarized. Application of PCA and RDA is illustrated in

  7. Nuclear techniques for toxic elements in foodstuffs. Report on an IAEA co-ordinated research programme

    International Nuclear Information System (INIS)

    1994-01-01

    The document includes 10 final reports on the IAEA Co-ordinated Research Programme on Nuclear Techniques for Toxic Elements in Foodstuffs. A separate abstract was prepared for each report. Refs, figs and tabs

  8. Spatial Treatment of the Slab-geometry Discrete Ordinates Equations Using Artificial Neural Networks

    International Nuclear Information System (INIS)

    Brantley, P S

    2001-01-01

    An artificial neural network (ANN) method is developed for treating the spatial variable of the one-group slab-geometry discrete ordinates (S N ) equations in a homogeneous medium with linearly anisotropic scattering. This ANN method takes advantage of the function approximation capability of multilayer ANNs. The discrete ordinates angular flux is approximated by a multilayer ANN with a single input representing the spatial variable x and N outputs representing the angular flux in each of the discrete ordinates angular directions. A global objective function is formulated which measures how accurately the output of the ANN approximates the solution of the discrete ordinates equations and boundary conditions at specified spatial points. Minimization of this objective function determines the appropriate values for the parameters of the ANN. Numerical results are presented demonstrating the accuracy of the method for both fixed source and incident angular flux problems

  9. Time dependence linear transport III convergence of the discrete ordinate method

    International Nuclear Information System (INIS)

    Wilson, D.G.

    1983-01-01

    In this paper the uniform pointwise convergence of the discrete ordinate method for weak and strong solutions of the time dependent, linear transport equation posed in a multidimensional, rectangular parallelepiped with partially reflecting walls is established. The first result is that a sequence of discrete ordinate solutions converges uniformly on the quadrature points to a solution of the continuous problem provided that the corresponding sequence of truncation errors for the solution of the continuous problem converges to zero in the same manner. The second result is that continuity of the solution with respect to the velocity variables guarantees that the truncation erros in the quadrature formula go the zero and hence that the discrete ordinate approximations converge to the solution of the continuous problem as the discrete ordinate become dense. An existence theory for strong solutions of the the continuous problem follows as a result

  10. Ordinance on the Carriage of Dangerous Goods by Rail (GGVE). 2. rev. and enl. ed.

    International Nuclear Information System (INIS)

    Ridder, K.; Katholnig, F.

    1993-01-01

    The book presents the legislative texts and other legal provisions concerning the transport of dangerous goods by rail: (1) Act on the transport of dangerous goods, full text. (2) Ordinance on the carriage of dangerous goods by rail (GGVE) - GGVE skeleton ordinance; Annex to the skeleton ordinance. (3) Documents - GGVE implementing regulations RE 001; R 002; Ordinance on exeptions GGVE; Extracts from IAEA recommendations concerning safe transport of radioactive materials; catalogue of fines pertaining to section 10 GGVE. (4) Alphabetical list of materials for GGVE/RID and GGVS/ADR. Index terms printed in deep black at the margin of pages allow quick access to the text passages of interest, and there is a subject index for retrieval over the entire book. (orig./HP) [de

  11. The Outlier Detection for Ordinal Data Using Scalling Technique of Regression Coefficients

    Science.gov (United States)

    Adnan, Arisman; Sugiarto, Sigit

    2017-06-01

    The aims of this study is to detect the outliers by using coefficients of Ordinal Logistic Regression (OLR) for the case of k category responses where the score from 1 (the best) to 8 (the worst). We detect them by using the sum of moduli of the ordinal regression coefficients calculated by jackknife technique. This technique is improved by scalling the regression coefficients to their means. R language has been used on a set of ordinal data from reference distribution. Furthermore, we compare this approach by using studentised residual plots of jackknife technique for ANOVA (Analysis of Variance) and OLR. This study shows that the jackknifing technique along with the proper scaling may lead us to reveal outliers in ordinal regression reasonably well.

  12. Ordinance of 17 May 1978 on definitions and licences in the atomic energy field

    International Nuclear Information System (INIS)

    1978-01-01

    This Ordinance came into force on 1 July 1978. It enables the Swiss authorities to apply the provisions of the Treaty on the Non-Proliferation of Nuclear Weapons and the guidelines on the transfer of nuclear material and equipment of the group of nuclear supplier countries (London Club) according to the IAEA document INFCIRC 254. The Ordinance is supplemented by annexes and appendices which list and specify the material, reactors and equipment which are subject to an export licence. The Federal Office of Energy Economy issues the licences required for the import and export of such material and equipment. Finally, this Ordinance repeals the Ordinance of 13 June 1960 on Definitions and Permits in the Atomic Energy Field. (NEA) [fr

  13. The discrete ordinates method for solving the azimuthally dependent transport equation in plane geometry

    International Nuclear Information System (INIS)

    Chalhoub, Ezzat Selim

    1997-01-01

    The method of discrete ordinates is applied to the solution of the slab albedo problem with azimuthal dependence in transport theory. A new set of quadratures appropriate to the problem is introduced. In addition to the ANISN code, modified to include the proposed formalism, two new programs, PEESNC and PEESNA, which were created on the basis of the discrete ordinates formalism, using the direct integration method and the analytic solution method respectively, are used in the generation of results for a few sample problems. Program PEESNC was created to validate the results obtained with the discrete ordinates method and the finite difference approximation (ANISN), while program PEESNA was developed in order to implement an analytical discrete ordinates formalism, which provides more accurate results. The obtained results for selected sample problems are compared with highly accurate numerical results published in the literature. Compared to ANISN and PEESNC, program PEESNA presents a greater efficiency in execution time and much more precise numerical results. (author)

  14. Neural network modeling to support an experimental study of the delignification process of sugarcane bagasse after alkaline hydrogen peroxide pre-treatment.

    Science.gov (United States)

    Valim, Isabelle C; Fidalgo, Juliana L G; Rego, Artur S C; Vilani, Cecília; Martins, Ana Rosa F A; Santos, Brunno F

    2017-11-01

    The present study examines the use of Artificial Neural Networks (ANN) as prediction and fault detection tools for the delignification process of sugarcane bagasse via hydrogen peroxide (H 2 O 2 ). Experimental conditions varied from 25 to 45°C for temperature and from 1.5% to 7.5% (v/v) for H 2 O 2 concentrations. Analytical results for the delignification were obtained by Fourier Transform Infrared (FT-IR) analysis and used for the ANN training and testing steps, allowing for the development of ANN models. The condition experimentally identified as the most suitable for the delignification process was of 25°C with 4.5% (v/v) H 2 O 2 , oxidizing 54% of total lignin. An ANN topology was selected for each proposed model, whose performance was evaluated by the correlation coefficient (R 2 ) and error indices (MSE and SSE). The values obtained for R 2 and the error indices indicated good agreements of the theoretical and actual data, of close to 1 and close to 0, respectively. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. Modification of 28 November 1983 of the Radiation Protection ordinance of 30 June 1976

    International Nuclear Information System (INIS)

    1983-01-01

    This Ordinance modifies the 1976 Radiation Protection Ordinance. The amendment allocates responsibility for radiation control among various governmental bodies. The Federal Office of Public Health is responsible for all radiation protection controls whenever they involve the protection of the public at large and the Accident Insurance Office is responsible for the protection of workers. Radiation control in nuclear installations is the responsibility of the Principal Division for the Safety of Nuclear Installations. (NEA) [fr

  16. Associations of motor co-ordination and attention with motor-perceptual development in 3-year-old preterm and full-term children who needed neonatal intensive care.

    Science.gov (United States)

    Hemgren, E; Persson, K

    2007-01-01

    Children who have needed neonatal intensive care (NIC) are considered to be at risk for deficits such as developmental co-ordination disorder and attention-deficit/hyperactivity disorder. By assessing motor-perceptual development, motor co-ordination and attention already at 3 years of age, it might be possible to identify such deficits earlier than they are today. To investigate the motor-perceptual development in a group of 202 NIC children but had no major impairments, to describe associations of deficits in co-ordination and attention with motor-perceptual delays, and to estimate the prevalence of NIC children with combined deficits together with a motor-perceptual delay. Co-ordination and attention in children born very preterm (n = 57), moderately preterm (n = 75) and full-term (n = 70) were observed according to a model for Combined Assessment of Motor Performance and Behaviour while they were assessed using a developmental scale, Motor-Perceptual Development, 0-7 years, MPU. In two out of 14 MPU areas, a larger proportion of very preterm than of moderately preterm and full-term children had marked developmental delay. Overall, the proportion of NIC children having a motor-perceptual delay increased with increasing incoordination and especially increasing lack of attention. Twenty-one (11%) of the NIC children had different motor-perceptual delays combined with pronounced incoordination and pronounced lack of attention. Deficits in co-ordination and attention were associated with motor-perceptual delays in areas important for daily living and development of academic skills. Therefore, to find children at risk for developmental co-ordination disorder and attention-deficit/hyperactivity disorder, assessments of co-ordination and attention should be added to assessments of motor-perceptual development in 3-year-old NIC children.

  17. Discrete-ordinates finite-element method for atmospheric radiative transfer and remote sensing

    International Nuclear Information System (INIS)

    Gerstl, S.A.W.; Zardecki, A.

    1985-01-01

    Advantages and disadvantages of modern discrete-ordinates finite-element methods for the solution of radiative transfer problems in meteorology, climatology, and remote sensing applications are evaluated. After the common basis of the formulation of radiative transfer problems in the fields of neutron transport and atmospheric optics is established, the essential features of the discrete-ordinates finite-element method are described including the limitations of the method and their remedies. Numerical results are presented for 1-D and 2-D atmospheric radiative transfer problems where integral as well as angular dependent quantities are compared with published results from other calculations and with measured data. These comparisons provide a verification of the discrete-ordinates results for a wide spectrum of cases with varying degrees of absorption, scattering, and anisotropic phase functions. Accuracy and computational speed are also discussed. Since practically all discrete-ordinates codes offer a builtin adjoint capability, the general concept of the adjoint method is described and illustrated by sample problems. Our general conclusion is that the strengths of the discrete-ordinates finite-element method outweight its weaknesses. We demonstrate that existing general-purpose discrete-ordinates codes can provide a powerful tool to analyze radiative transfer problems through the atmosphere, especially when 2-D geometries must be considered

  18. Experiences in the parallelization of the discrete ordinates method using OpenMP and MPI

    International Nuclear Information System (INIS)

    Pautz, A.; Langenbuch, S.

    2003-01-01

    The method of Discrete Ordinates is in principle parallelizable to a high degree, since the transport 'mesh sweeps' are mutually independent for all angular directions. However, in the well-known production code Dort such a type of angular domain decomposition has to be done on a spatial line-byline basis, causing the parallelism in the code to be very fine-grained. The construction of scalar fluxes and moments requires a large effort for inter-thread or inter-process communication. We have implemented two different parallelization approaches in Dort: firstly, we have used a shared-memory model suitable for SMP (Symmetric Multiprocessor) machines based on the standard OpenMP. The second approach uses the well-known Message Passing Interface (MPI) to establish communication between parallel processes running in a distributed-memory environment. We investigate the benefits and drawbacks of both models and show first results on performance and scaling behaviour of the parallel Dort code. (authors)

  19. Suppression of Methamphetamine Self-Administration by Ketamine Pre-treatment Is Absent in the Methylazoxymethanol (MAM) Rat Model of Schizophrenia.

    Science.gov (United States)

    Ruda-Kucerova, Jana; Babinska, Zuzana; Stark, Tibor; Micale, Vincenzo

    2017-07-01

    Ketamine may prove to be a potential candidate in treating the widespread drug addiction/substance abuse epidemic among patients with schizophrenia. Clinical studies have shown ketamine to reduce cocaine and heroin cravings. However, the use of ketamine remains controversial as it may exacerbate the symptoms of schizophrenia. Therefore, the aim of this study is to characterize the effects of ketamine on drug addiction in schizophrenia using the methylazoxymethanol (MAM) acetate rat model on operant IV methamphetamine (METH) self-administration. MAM was administered intraperitoneally (22 mg/kg) on gestational day 17. Locomotor activity test and later IV self-administration (IVSA) were then performed in the male offspring followed by a period of forced abstinence and relapse of METH taking. After reaching stable intakes in the relapse phase, ketamine (5 mg/kg) was administered intraperitoneally 30 min prior to the self-administration session. As documented previously, the MAM rats showed a lack of habituation in the locomotor activity test but developed stable maintenance of METH self-administration with no difference in operant behaviour to control animals. Results show that ketamine treatment significantly reduced the METH intake in the control animals but not in MAM animals. Ketamine effect on METH self-administration may be explained by increased glutamatergic signalling in the prefrontal cortex caused by the N-methyl-D-aspartate antagonism and disinhibition of GABA interneurons which was shown to be impaired in the MAM rats. This mechanism may at least partly explain the clinically proven anti-craving potential of ketamine and allow development of more specific anti-craving medications with fewer risks.

  20. Discrete ordinates solution of coupled conductive radiative heat transfer in a two-layer slab with Fresnel interfaces subject to diffuse and obliquely collimated irradiation

    International Nuclear Information System (INIS)

    Muresan, Cristian; Vaillon, Rodolphe; Menezo, Christophe; Morlot, Rodolphe

    2004-01-01

    The coupled conductive radiative heat transfer in a two-layer slab with Fresnel interfaces subject to diffuse and obliquely collimated irradiation is solved. The collimated and diffuse components problems are treated separately. The solution for diffuse radiation is obtained by using a composite discrete ordinates method and includes the development of adaptive directional quadratures to overcome the difficulties usually encountered at the interfaces. The complete radiation numerical model is validated against the predictions obtained by using the Monte Carlo method

  1. pH catalyzed pretreatment of corn bran for enhanced enzymatic arabinoxylan degradation

    DEFF Research Database (Denmark)

    Agger, Jane; Johansen, Katja Salomon; Meyer, Anne S.

    2011-01-01

    Corn bran is mainly made up of the pericarp of corn kernels and is a byproduct stream resulting from the wet milling step in corn starch processing. Through statistic modeling this study examined the optimization of pretreatment of corn bran for enzymatic hydrolysis. A low pH pretreatment (pH 2......, 150°C, 65min) boosted the enzymatic release of xylose and glucose and maximized biomass solubilization. With more acidic pretreatment followed by enzymatic hydrolysis the total xylose release was maximized (at pH 1.3) reaching ∼50% by weight of the original amount present in destarched corn bran......, but the enzyme catalyzed xylose release was maximal after pretreatment at approx. pH 2. The total glucose release peaked after pretreatment of approx. pH 1.5 with an enzymatic release of approx. 68% by weight of the original amounts present in destarched corn bran. For arabinose the enzymatic release...

  2. Optimisation of dilute acid pre-treatment of artisan rice hulls for ethanol production

    International Nuclear Information System (INIS)

    Lopez, Yoney; Martin, Carlos; Gullon, Beatriz; Parajo, Juan Carlos

    2011-01-01

    Rice hulls are potential low-cost feedstocks for fuel ethanol production in many countries. In this work, the dilute-acid pre-treatment of artisan rice hulls was investigated using a central composite rotatable experimental design. The experimental variables were temperature (140-210 C), biomass load (5-20%) and sulphuric acid concentration (0.5-1.5 g per 100 g of reaction mixture). A total of 16 experimental runs, including a 23-plan, two replicates at the central point and six star points, were carried out. Low temperatures were found to be favourable for the hydrolysis of xylan and of the easily hydrolyzable glucan fraction. High glucose formation (up to 15.3 g/100 g), attributable to starch hydrolysis, was detected in the hydrolysates obtained under the least severe pre-treatment conditions. Using the experimental results, several models for predicting the effect of the operational conditions on the yield of pretreated solids, xylan and glucan conversion upon pre-treatment, and on enzymatic convertibility of cellulose were developed. Optimum results were predicted for the conversion of easily-hydrolyzable glucan in the material pretreated at 140.7 C, and for the enzymatic saccharification of cellulose in the material pretreated at 169 C. These results suggested the use of two-step acid hydrolysis as future pre-treatment strategy for artisan rice hulls. Key words: Dilute acid hydrolysis, enzymatic hydrolysis, pre-treatment, rice hulls. (author)

  3. Wash water waste pretreatment system

    Science.gov (United States)

    1977-01-01

    Investigations were completed on wash waters based on each candidate personal cleansing agent. Evaluations of coagulants, antifoam agents, and the effect of promising antifoams on the chemical precipitation were included. Based on these evaluations two candidate soaps as well as their companion antifoam agents were selected for further work. Operating parameters included the effect of soap concentration, ferric chloride concentration, duration of mixing, and pore size of depth filters on the degree of soap removal. The effect of pressure on water flow through filter cartridges and on the rate of decline of water flow was also investigated. The culmination of the program was the recommendation of a pretreatment concept based on chemical precipitation followed by pressure filtration.

  4. Electrohydrolysis pretreatment for enhanced methane production from lignocellulose waste pulp and paper mill sludge and its kinetics.

    Science.gov (United States)

    Veluchamy, C; Raju, V Wilson; Kalamdhad, Ajay S

    2018-03-01

    A novel electrohydrolysis pretreatment enhances methane production from lignocellulose material during anaerobic digestion. A biochemical methane potential assay was carried out to determine the effect of direct current and the efficacy of electrohydrolysis pretreatment on biogas production. Methane yield was increased by 13.8%, to 301 ± 3 mL CH 4 /g VS, when lignocellulosic waste was pretreated with electrohydrolysis. A net energy gain of 13,224 kJ was realized after electrohydrolysis pretreatment, which was 1.51 times higher than reported for thermal pretreatment. In addition, two kinetic models were used, including the modified Gompertz model to reproduce the experimental data. These finding support the potential for increased methane recovery from lignocellulosic waste using electrohydrolysis as a pretreatment. Copyright © 2017 Elsevier Ltd. All rights reserved.

  5. A real explosion: the requirement of steam explosion pretreatment.

    Science.gov (United States)

    Yu, Zhengdao; Zhang, Bailiang; Yu, Fuqiang; Xu, Guizhuan; Song, Andong

    2012-10-01

    The severity factor is a common term used in steam explosion (SE) pretreatment that describes the combined effects of the temperature and duration of the pretreatment. However, it ignores the duration of the explosion process. This paper describes a new parameter, the explosion power density (EPD), which is independent of the severity factor. Furthermore, we present the adoption of a 5m(3) SE model for a catapult explosion mode, which completes the explosion within 0.0875 s. The explosion duration ratio of this model to a conventional model of the same volume is 1:123. The comparison between the two modes revealed a qualitative change by explosion speed, demonstrating that this real explosion satisfied the two requirements of consistency, and suggested a guiding mechanism for the design of SE devices. Copyright © 2012 Elsevier Ltd. All rights reserved.

  6. Care co-ordination for older people in the third sector: scoping the evidence.

    Science.gov (United States)

    Abendstern, Michele; Hughes, Jane; Jasper, Rowan; Sutcliffe, Caroline; Challis, David

    2017-01-24

    The third sector has played a significant role internationally in the delivery of adult social care services for many years. Its contribution to care co-ordination activities for older people, however, in England and elsewhere, is relatively unknown. A scoping review was therefore conducted to ascertain the character of the literature, the nature and extent of third sector care co-ordination activity, and to identify evidence gaps. It was undertaken between autumn 2013 and summer 2014 and updated with additional searches in 2016. Electronic and manual searches of international literature using distinct terms for different approaches to care co-ordination were undertaken. From a total of 835 papers, 26 met inclusion criteria. Data were organised in relation to care co-ordination approaches, types of third sector organisation and care recipients. Papers were predominantly from the UK and published this century. Key findings included that: a minority of literature focused specifically on older people and that those doing so described only one care co-ordination approach; third sector services tended to be associated with independence and person-centred practice; and working with the statutory sector, a prerequisite of care co-ordination, was challenging and required a range of features to be in place to support effective partnerships. Strengths and weaknesses of care co-ordination practice in the third sector according to key stakeholder groups were also highlighted. Areas for future research included the need for: a specific focus on older people's experiences; an investigation of workforce issues; detailed examination of third sector practices, outcomes and costs; interactions with the statutory sector; and an examination of quality assurance systems and their appropriateness to third sector practice. The main implication of the findings is a need to nurture variety within the third sector in order to provide older people and other adults with the range of service

  7. Delignification kinetics of corn stover in lime pretreatment.

    Science.gov (United States)

    Kim, Sehoon; Holtzapple, Mark T

    2006-03-01

    Corn stover was pretreated with excess calcium hydroxide (0.5 g Ca(OH)(2)/g raw biomass) in non-oxidative and oxidative conditions at 25, 35, 45, and 55 degrees C. The delignification kinetic model of corn stover used three first-order reactions with following forms: W(L) = 0.09 x exp(-infinity x t) + 0.28 x exp(-k(2) x t) + 0.63 x exp(-k(3) x t) in non-oxidative pretreatment; W(L) = 0.16 x exp(-infinity x t) + 0.27 x exp(-k(2) x t) + 0.57 x exp(-k(3) x t) in oxidative pretreatment. The first term corresponds to the initial phase, which is essentially infinite at the time scale of the reaction (weeks). The second and third terms correspond to the bulk and residual phases of delignification. The activation energies for delignification in the oxidative lime pretreatment reactions were estimated as 50.15 and 54.21 kJ/mol in the bulk and residual phases, respectively, which are similar to the Kraft delignification of bagasse, but much less than in Kraft delignification of wood.

  8. Levels of disability in the older population of England: Comparing binary and ordinal classifications.

    Science.gov (United States)

    Pongiglione, Benedetta; Ploubidis, George B; De Stavola, Bianca L

    2017-10-01

    Recent studies suggest the importance of distinguishing severity levels of disability. Nevertheless, there is not yet a consensus with regards to an optimal classification. Our study seeks to advance the existing binary definitions towards categorical/ordinal manifestations of disability. We define disability according to the WHO's International Classification of Functioning, Disability and Health (ICF) using data collected at the baseline wave of the English Longitudinal Study of Aging, a longitudinal study of the non-institutionalized population, living in England. First, we identify cut-off points in the continuous disability score derived from ICF to distinguish disabled from no-disabled participants. Then, we fit latent class models to the same data to find the optimal number of disability classes according to: (i) model fit indicators; (ii) estimated probabilities of each disability item; (iii) association of the predicted disability classes with observed health and mortality. According to the binary classification criteria, about 32% of both men and women are classified disabled. No optimal number of classes emerged from the latent class models according to model fit indicators. However, the other two criteria suggest that the best-fitting model of disability severity has four classes. Our findings contribute to the debate on the usefulness and relevance of adopting a finer categorization of disability, by showing that binary indicators of disability averaged the burden of disability and masked the very strong effect experienced by individuals having severe disability, and were not informative for low levels of disability. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

  9. A Hybrid Heuristic Optimization Approach for Leak Detection in Pipe Networks Using Ordinal Optimization Approach and the Symbiotic Organism Search

    Directory of Open Access Journals (Sweden)

    Chao-Chih Lin

    2017-10-01

    Full Text Available A new transient-based hybrid heuristic approach is developed to optimize a transient generation process and to detect leaks in pipe networks. The approach couples the ordinal optimization approach (OOA and the symbiotic organism search (SOS to solve the optimization problem by means of iterations. A pipe network analysis model (PNSOS is first used to determine steady-state head distribution and pipe flow rates. The best transient generation point and its relevant valve operation parameters are optimized by maximizing the objective function of transient energy. The transient event is created at the chosen point, and the method of characteristics (MOC is used to analyze the transient flow. The OOA is applied to sift through the candidate pipes and the initial organisms with leak information. The SOS is employed to determine the leaks by minimizing the sum of differences between simulated and computed head at the observation points. Two synthetic leaking scenarios, a simple pipe network and a water distribution network (WDN, are chosen to test the performance of leak detection ordinal symbiotic organism search (LDOSOS. Leak information can be accurately identified by the proposed approach for both of the scenarios. The presented technique makes a remarkable contribution to the success of leak detection in the pipe networks.

  10. Optimizing nitrogen fertilizer application to irrigated wheat. Results of a co-ordinated research project. 1994-1998

    International Nuclear Information System (INIS)

    2000-07-01

    This TECDOC summarizes the results of a Co-ordinated Research Project (CRP) on the Use of Nuclear Techniques for Optimizing Fertilizer Application under Irrigated Wheat to Increase the Efficient Use of Nitrogen Fertilizer and Consequently Reduce Environmental Pollution. The project was carried out between 1994 and 1998 through the technical co-ordination of the Joint FAO/IAEA Division of Nuclear Techniques in Food and Agriculture. Fourteen Member States of the IAEA and FAO carried out a series of field experiments aimed at improving irrigation water and fertilizer-N uptake efficiencies through integrated management of the complex Interactions involving inputs, soils, climate, and wheat cultivars. Its goals were: to investigate various aspects of fertilizer N uptake efficiency of wheat crops under irrigation through an interregional research network involving countries growing large areas of irrigated wheat; to use 15 N and the soil-moisture neutron probe to determine the fate of applied N, to follow water and nitrate movement in the soil, and to determine water balance and water-use efficiency in irrigated wheat cropping systems; to use the data generated to further develop and refine various relationships in the Ceres-Wheat computer simulation model; to use the knowledge generated to produce a N-rate-recommendation package to refine specific management strategies with respect to fertilizer applications and expected yields

  11. A Novel Method for Detection of Epilepsy in Short and Noisy EEG Signals Using Ordinal Pattern Analysis

    Directory of Open Access Journals (Sweden)

    Iman Veisi

    2010-03-01

    Full Text Available Introduction: In this paper, a novel complexity measure is proposed to detect dynamical changes in nonlinear systems using ordinal pattern analysis of time series data taken from the system. Epilepsy is considered as a dynamical change in nonlinear and complex brain system. The ability of the proposed measure for characterizing the normal and epileptic EEG signals when the signal is short or is contaminated with noise is investigated and compared with some traditional chaos-based measures. Materials and Methods: In the proposed method, the phase space of the time series is reconstructed and then partitioned using ordinal patterns. The partitions can be labeled using a set of symbols. Therefore, the state trajectory is converted to a symbol sequence. A finite state machine is then constructed to model the sequence. A new complexity measure is proposed to detect dynamical changes using the state transition matrix of the state machine. The proposed complexity measure was applied to detect epilepsy in short and noisy EEG signals and the results were compared with some chaotic measures. Results: The results indicate that this complexity measure can distinguish normal and epileptic EEG signals with an accuracy of more than 97% for clean EEG and more than 75% for highly noised EEG signals. Discussion and Conclusion: The complexity measure can be computed in a very fast and easy way and, unlike traditional chaotic measures, is robust with respect to noise corrupting the data. This measure is also capable of dynamical change detection in short time series data.

  12. Discrete ordinates transport methods for problems with highly forward-peaked scattering

    International Nuclear Information System (INIS)

    Pautz, S.D.

    1998-04-01

    The author examines the solutions of the discrete ordinates (S N ) method for problems with highly forward-peaked scattering kernels. He derives conditions necessary to obtain reasonable solutions in a certain forward-peaked limit, the Fokker-Planck (FP) limit. He also analyzes the acceleration of the iterative solution of such problems and offer improvements to it. He extends the analytic Fokker-Planck limit analysis to the S N equations. This analysis shows that in this asymptotic limit the S N solution satisfies a pseudospectral discretization of the FP equation, provided that the scattering term is handled in a certain way (which he describes) and that the analytic transport solution satisfies an analytic FP equation. Similar analyses of various spatially discretized S N equations reveal that they too produce solutions that satisfy discrete FP equations, given the same provisions. Numerical results agree with these theoretical predictions. He defines a multidimensional angular multigrid (ANMG) method to accelerate the iterative solution of highly forward-peaked problems. The analyses show that a straightforward application of this scheme is subject to high-frequency instabilities. However, by applying a diffusive filter to the ANMG corrections he is able to stabilize this method. Fourier analyses of model problems show that the resulting method is effective at accelerating the convergence rate when the scattering is forward-peaked. The numerical results demonstrate that these analyses are good predictors of the actual performance of the ANMG method

  13. Co-ordinated research and environmental surveillance programme related to sea disposal of radioactive waste

    International Nuclear Information System (INIS)

    1984-01-01

    Sea disposal operations of packaged low-level radioactive waste are carried out under the provisions of the Convention on the Prevention of Marine Pollution by Dumping of Wastes and Other Matter, also referred to as the London Dumping Convention. The environmental impact of this disposal method is continuously kept under review, in particular within the IAEA which has provided the ''Definition of High-Level Radioactive Waste or Other High-Level Radioactive Matter Unsuitable for Dumping at Sea'' for the purpose of the Convention and within the OECD-NEA in the framework of its Multilateral Consultation and Surveillance Mechanism for Sea Dumping of Radioactive Waste. The NEA Co-Ordinated Research and Environmental Surveillance Programme (CRESP) is focussed on the actual North-East Atlantic dump site. Its objective is to increase the available scientific data base related to the oceanographic and biological characteristics of the dump site and elaborate a site specific model of the transfers of radionuclides to human populations. Future site suitability reviews, as periodically requested under the terms of the Multilateral Consultation and Surveillance Mechanism, will therefore be based on a more accurate and comprehensive scientific basis

  14. Monte Carlo and discrete-ordinate simulations of irradiances in the coupled atmosphere-ocean system.

    Science.gov (United States)

    Gjerstad, Karl Idar; Stamnes, Jakob J; Hamre, Børge; Lotsberg, Jon K; Yan, Banghua; Stamnes, Knut

    2003-05-20

    We compare Monte Carlo (MC) and discrete-ordinate radiative-transfer (DISORT) simulations of irradiances in a one-dimensional coupled atmosphere-ocean (CAO) system consisting of horizontal plane-parallel layers. The two models have precisely the same physical basis, including coupling between the atmosphere and the ocean, and we use precisely the same atmospheric and oceanic input parameters for both codes. For a plane atmosphere-ocean interface we find agreement between irradiances obtained with the two codes to within 1%, both in the atmosphere and the ocean. Our tests cover case 1 water, scattering by density fluctuations both in the atmosphere and in the ocean, and scattering by particulate matter represented by a one-parameter Henyey-Greenstein (HG) scattering phase function. The CAO-MC code has an advantage over the CAO-DISORT code in that it can handle surface waves on the atmosphere-ocean interface, but the CAO-DISORT code is computationally much faster. Therefore we use CAO-MC simulations to study the influence of ocean surface waves and propose a way to correct the results of the CAO-DISORT code so as to obtain fast and accurate underwater irradiances in the presence of surface waves.

  15. On the spectral nodal methods applied to discrete ordinates eigenvalue problems in Cartesian geometry

    International Nuclear Information System (INIS)

    Abreu, Marcos P. de; Alves Filho, Hermes; Barros, Ricardo C.

    2001-01-01

    We describe hybrid spectral nodal methods for discrete ordinates (SN) eigenvalue problems in Cartesian geometry. These coarse-mesh methods are based on three ingredients: the use of the standard discretized spatial balance SN equations; the use of the non-standard spectral diamond (SD) auxiliary equations in the multiplying regions of the domain, e.g. fuel assemblies; and the use of the non-standard spectral Green's function (SGF) auxiliary equations in the non-multiplying regions of the domain, e.g., the reflector. In slab-geometry the hybrid SD-SGF method generates numerical results that are completely free of spatial truncation errors. In X,Y-geometry, we obtain a system of two 'slab-geometry' SN equations for the node-edge average angular fluxes by transverse-integrating the X,Y-geometry SN equations separately in the y- and then in the x-directions within an arbitrary node of the spatial grid set up on the domain. In this paper, we approximate the transverse leakage terms by constants. These are the only approximations considered in the SD-SGF-constant nodal method, as the source terms, that include scattering and eventually fission events, are treated exactly. We show numerical results to typical model problems to illustrate the accuracy of spectral nodal methods for coarse-mesh SN criticality calculations. (author)

  16. Study on the Algorithm for Train Operation Adjustment Based on Ordinal Optimization

    Directory of Open Access Journals (Sweden)

    Yong-jun Chen

    2013-01-01

    Full Text Available It is a crucial and difficult problem in railway transportation dispatch mechanism to automatically compile train operation adjustment (TOA plan with computer to ensure safe, fast, and punctual running of trains. Based on the proposed model of TOA under the conditions of railway network (RN, we take minimum travel time of train as objective function of optimization, and after fast preliminary evaluation calculation on it, we introduce the theory and method of ordinal optimization (OO to solve it. This paper discusses in detail the implementation steps of OO algorithm. A practical calculation example of Datong-Qinhuangdao (hereinafter referred to as Da-Qin heavy haul railway is performed with the proposed algorithm to prove that OO can ensure getting good enough solution with high probability. Particularly, for complex optimization problems with large amount of calculation, OO can greatly increase computational efficiency, and it can save at least one order of magnitude of calculation amount than general heuristic algorithm. Thus, the proposed algorithm can well satisfy the requirements in engineering.

  17. Pretreatment of the macroalgae Chaetomorpha linum for the production of bioethanol - Comparison of five pretreatment technologies

    DEFF Research Database (Denmark)

    Schultz-Jensen, Nadja; Thygesen, Anders; Thomsen, Sune Tjalfe

    2013-01-01

    -assisted pretreatment (PAP) and ball milling (BM), to determine effects of the pretreatment methods on the conversion of C. linum into ethanol by simultaneous saccharification and fermentation (SSF). WO and BM showed the highest ethanol yield of 44. g ethanol/100. g glucan, which was close to the theoretical ethanol......A qualified estimate for pretreatment of the macroalgae Chaetomorpha linum for ethanol production was given, based on the experience of pretreatment of land-based biomass. C. linum was subjected to hydrothermal pretreatment (HTT), wet oxidation (WO), steam explosion (STEX), plasma...... yield of 57. g ethanol/100. g glucan. A 64% higher ethanol yield, based on raw material, was reached after pretreatment with WO and BM compared with unpretreated C. linum, however 50% of the biomass was lost during WO. Results indicated that the right combination of pretreatment and marine macroalgae...

  18. Spatial coding of ordinal information in short- and long-term memory

    Science.gov (United States)

    Ginsburg, Véronique; Gevers, Wim

    2015-01-01

    The processing of numerical information induces a spatial response bias: Faster responses to small numbers with the left hand and faster responses to large numbers with the right hand. Most theories agree that long-term representations underlie this so called SNARC effect (Spatial Numerical Association of Response Codes; Dehaene et al., 1993). However, a spatial response bias was also observed with the activation of temporary position-space associations in working memory (ordinal position effect; van Dijck and Fias, 2011). Items belonging to the beginning of a memorized sequence are responded to faster with the left hand side while items at the end of the sequence are responded to faster with the right hand side. The theoretical possibility was put forward that the SNARC effect is an instance of the ordinal position effect, with the empirical consequence that the SNARC effect and the ordinal position effect cannot be observed simultaneously. In two experiments we falsify this claim by demonstrating that the SNARC effect and the ordinal position effect are not mutually exclusive. Consequently, this suggests that the SNARC effect and the ordinal position effect result from the activation of different representations. We conclude that spatial response biases can result from the activation of both pre-existing positions in long-term memory and from temporary space associations in working memory at the same time. PMID:25688199

  19. The Impact of the 2002 Delaware Smoking Ordinance on Heart Attack and Asthma

    Directory of Open Access Journals (Sweden)

    Luis H. Solis

    2010-12-01

    Full Text Available In the United States, smoking is the leading cause of death - having a mortality rate of approximately 435,000 people in 2000—accounting for 8.1% of all US deaths recorded that year. Consequently, we analyzed the Delaware Hospital Discharge Database, and identified state and non-state residents discharged with AMI or asthma for the years 1999 to 2004. Statistical data analysis compared the incidence of AMI or asthma for each group before (1999–2002 and after (2003–2004 the amendment. As a result, we found that pre-ordinance and post-ordinance quarterly rates of AMI for Delaware residents were 451 (se = 21 and 430 (se = 21 respectively, representing a 4.7% reduction. Over the same time period, there was negligible change in the incidence of AMI for non-Delaware residents. After adjusting for population growth, the Risk Ratio (RR for asthma in Delaware residents post-ordinance was 0.95 (95% CI, 0.90 to 0.999, which represented a significant reduction (P = 0.046. By comparison, non-Delaware residents had an increased RR for asthma post-ordinance of 1.62 (95% CI, 1.46 to 1.86; P < 0.0001.The results suggest that Delaware’s comprehensive non-smoking ordinance effectively was associated with a statistically significant decrease in the incidence of AMI and asthma in Delaware residents when compared to non-Delaware residents.

  20. Spatial coding of ordinal information in short- and long-term memory

    Directory of Open Access Journals (Sweden)

    Veronique eGinsburg

    2015-01-01

    Full Text Available The processing of numerical information induces a spatial response bias: Faster responses to small numbers with the left hand and faster responses to large numbers with the right hand. Most theories agree that long-term representations underlie this so called SNARC effect (Spatial Numerical Association of Response Codes; Dehaene, Bossini, & Giraux, 1993. However, a spatial response bias was also observed with the activation of temporary position-space associations in working memory (ordinal position effect; van Dijck & Fias, 2011. Items belonging to the beginning of a memorized sequence are responded to faster with the left hand side while items at the end of the sequence are responded to faster with the right hand side. The theoretical possibility was put forward that the SNARC effect is an instance of the ordinal position effect, with the empirical consequence that the SNARC effect and the ordinal position effect cannot be observed simultaneously. In two experiments we falsify this claim by demonstrating that the SNARC effect and the ordinal position effect are not mutually exclusive. Consequently, this suggests that the SNARC effect and the ordinal position effect result from the activation of different representations. We conclude that spatial response biases can result from the activation of both pre-existing positions in long-term memory and from temporary space associations in working memory at the same time.

  1. Co-ordination of the upper and lower limbs for vestibular control of balance.

    Science.gov (United States)

    Smith, Craig P; Allsop, Jonathan E; Mistry, Michael; Reynolds, Raymond F

    2017-11-01

    When standing and holding an earth-fixed object, galvanic vestibular stimulation (GVS) can evoke upper limb responses to maintain balance. In the present study, we determined how these responses are affected by grip context (no contact, light grip and firm grip), as well as how they are co-ordinated with the lower limbs to maintain balance. When GVS was applied during firm grip, hand and ground reaction forces were generated. The directions of these force vectors were co-ordinated such that the overall body sway response was always aligned with the inter-aural axis (i.e. craniocentric). When GVS was applied during light grip (balance control and also that the upper and lower limbs co-ordinate for an appropriate whole-body sway response. Vestibular stimulation can evoke responses in the arm when it is used for balance. In the present study, we determined how these responses are affected by grip context, as well as how they are co-ordinated with the rest of the body. Galvanic vestibular stimulation (GVS) was used to evoke balance responses under three conditions of manual contact with an earth-fixed object: no contact, light grip (vestibular-evoked balance responses. Furthermore, they demonstrate that upper and lower-limb forces are co-ordinated to produce an appropriate whole-body sway response. © 2017 The Authors. The Journal of Physiology published by John Wiley & Sons Ltd on behalf of The Physiological Society.

  2. The impact of ordinate scaling on the visual analysis of single-case data.

    Science.gov (United States)

    Dart, Evan H; Radley, Keith C

    2017-08-01

    Visual analysis is the primary method for detecting the presence of treatment effects in graphically displayed single-case data and it is often referred to as the "gold standard." Although researchers have developed standards for the application of visual analysis (e.g., Horner et al., 2005), over- and underestimation of effect size magnitude is not uncommon among analysts. Several characteristics have been identified as potential contributors to these errors; however, researchers have largely focused on characteristics of the data itself (e.g., autocorrelation), paying less attention to characteristics of the graphic display which are largely in control of the analyst (e.g., ordinate scaling). The current study investigated the impact that differences in ordinate scaling, a graphic display characteristic, had on experts' accuracy in judgments regarding the magnitude of effect present in single-case percentage data. 32 participants were asked to evaluate eight ABAB data sets (2 each presenting null, small, moderate, and large effects) along with three iterations of each (32 graphs in total) in which only the ordinate scale was manipulated. Results suggest that raters are less accurate in their detection of treatment effects as the ordinate scale is constricted. Additionally, raters were more likely to overestimate the size of a treatment effect when the ordinate scale was constricted. Copyright © 2017 Society for the Study of School Psychology. Published by Elsevier Ltd. All rights reserved.

  3. Anatomical localization of electrophysiological recording sites by co-ordinate transformation.

    Science.gov (United States)

    Sinex, D G

    1997-07-18

    A method for estimating the anatomical locations of the units recorded in electrophysiological mapping experiments is described. A total of three locations must be marked by dye injections or electrolytic lesions and identified in tissue sections. From those locations, equations are derived to translate, scale, and rotate the three-dimensional co-ordinates of the recording sites, so that they are correct for a second, three-dimensional co-ordinate system based on the anatomy of the mapped structure. There is no limit to the number of recording sites that can be localized. This differs from methods that require a dye injection or lesion to be made at the exact location at which a particular unit was recorded. The accuracy of the transformed co-ordinates is limited by the accuracy with which the co-ordinates can be measured: in test measurements and in the experiments for which this algorithm was developed, the computed co-ordinates were typically accurate to within 100 microns or less.

  4. Development of three-dimensional program based on Monte Carlo and discrete ordinates bidirectional coupling method

    International Nuclear Information System (INIS)

    Han Jingru; Chen Yixue; Yuan Longjun

    2013-01-01

    The Monte Carlo (MC) and discrete ordinates (SN) are the commonly used methods in the design of radiation shielding. Monte Carlo method is able to treat the geometry exactly, but time-consuming in dealing with the deep penetration problem. The discrete ordinate method has great computational efficiency, but it is quite costly in computer memory and it suffers from ray effect. Single discrete ordinates method or single Monte Carlo method has limitation in shielding calculation for large complex nuclear facilities. In order to solve the problem, the Monte Carlo and discrete ordinates bidirectional coupling method is developed. The bidirectional coupling method is implemented in the interface program to transfer the particle probability distribution of MC and angular flux of discrete ordinates. The coupling method combines the advantages of MC and SN. The test problems of cartesian and cylindrical coordinate have been calculated by the coupling methods. The calculation results are performed with comparison to MCNP and TORT and satisfactory agreements are obtained. The correctness of the program is proved. (authors)

  5. Using infrared eye-tracking to explore ordinal numerical processing in toddlers with Fragile X Syndrome.

    Science.gov (United States)

    Owen, Emily R; Baumgartner, Heidi A; Rivera, Susan M

    2013-02-12

    Fragile X syndrome (FXS) is the most common cause of inherited intellectual disability and non-idiopathic autism. Individuals with FXS present with a behavioral phenotype of specific and selective deficits in an array of cognitive skills. Disruption of number processing and arithmetic abilities in higher-functioning adults and female adolescents with FXS has been well established. Still, both numerical skills and developmentally antecedent cognitive processes have just begun to be investigated in toddlers with FXS. The goal of the current study was to assess how very young children with FXS respond to ordinal relationships among numerical magnitudes. Infrared eye-tracking was used to explore infants' novelty recognition during passive viewing of ordinal numerical sequences; t-tests were used to analyze group differences in looking time. Ordinal recognition of numerical magnitudes is significantly impaired in young toddlers with FXS. This study is the first to experimentally evaluate early number sense and ordinal recognition in toddlers with FXS, and our findings reveal that ordinal recognition of numerical magnitudes is significantly impaired in young toddlers with FXS, suggesting that later arithmetic impairments associated with FXS may have their origins in a developmental impairment of this more basic aspect of numerical cognition.

  6. Restaurant volatility and the Iowa City, Iowa, smoke-free restaurant ordinance.

    Science.gov (United States)

    Sheffer, Megan A; Squier, Christopher A; Gilmore, Gary D

    2013-01-01

    To determine the economic impact of the Iowa City, Iowa, smoke-free restaurant ordinance (IC-SFRO) using an immediate and novel approach. In this retrospective study, food permit licensure served as the measure to assess the IC-SFRO impact. The Iowa City experience provided an excellent experimental setting, as the ordinance was enacted March 1, 2002, and repealed May 7, 2003, because of preemption. The city of Coralville served as a natural control, as it is contiguous to Iowa City, has similar population demographics, and has never enacted a smoke-free restaurant ordinance. Food permit licensure data for all Iowa City and Coralville restaurants were obtained from the Johnson County Health Department. Differences in restaurant volatility were assessed using Fisher's exact probability test. The number of restaurants increased in both Iowa City and Coralville throughout the ordinance period. The ratio of the total number of restaurants in Iowa City to the total number of restaurants in the Iowa City-Coralville metropolitan area remained stable. The proportion of restaurants for each city did not differ significantly during the preordinance, ordinance, and postordinance periods. The IC-SFRO did not adversely impact the restaurant industry in terms of restaurant closures. The Iowa legislature was urged to draft evidence-based legislation, such as amending preemption of the IC-SFRO, to protect and promote the health of its communities.

  7. The CONECOFOR Programme: general presentation, aims and co-ordination

    Directory of Open Access Journals (Sweden)

    Bruno PETRICCIONE

    2002-09-01

    damage (yearly have been added. Test phases of new surveys (biodiversity, biotic damage, etc. are planned for 2002/3. The National Forestry Service (CONECOFOR Service co-ordinates six participating research institutes, each of which is responsible for the analyses and monitoring activities. The permanent plots are selected according to the directive of EU Regulation no. 1091/94 so as to include the major forest ecosystems in Italy, and are distributed over the whole country. Each covers an area of 10-100 ha, within which two sample units of 2,500 m2 are designated. The main dominant species are Fagus sylvatica (10 areas, Picea abies (6, Quercus cerris (5, Quercus ilex (4, Quercus petraea (1 Quercus robur (1 and Abies alba (1. The first six years of the CONECOFOR Programme have resulted in a detailed, organic description of the main forest ecosystems in Italy. Implementation of the programme has meant that we are now in possession of a reasonably complete knowledge of the ecological characteristics of 17 different Italian forest communities ranging from the Alps to Sicily. The assessment and monitoring of forest health represent a key point for environmental policy-makers and for the management of environmental resources in the framework of sustainable development.

  8. Validation of models using Chernobyl fallout data from the Central Bohemia region of the Czech Republic. Scenario CB. First report of the VAMP Multiple Pathways Assessment Working Group. Part of the IAEA/CEC Co-ordinated Research Programme on the Validation of Environmental Model Predictions (VAMP)

    International Nuclear Information System (INIS)

    1995-04-01

    The VAMP Multiple Pathways Assessment Working Group is an international forum for the testing and comparison of model predictions. The emphasis is on evaluating transfer from the environment to human via all pathways which are relevant in the environment being considered. This document is the first report of the Group and contains the results of the first test exercise on the validation of multiple pathways assessment models using Chernobyl fallout data obtained from the Central Bohemia (CB) region of the Czech Republic (Scenario CB). The report includes the following three appendixes: Documentation and evaluation of model validation data used in scenario CB (3 papers), Description of models used in scenario CB (1 paper), Individual evaluations of model predictions for scenario CB (13 papers). A separate abstract was prepared for each paper. Refs, figs and tabs

  9. pH catalyzed pretreatment of corn bran for enhanced enzymatic arabinoxylan degradation.

    Science.gov (United States)

    Agger, Jane; Johansen, Katja Salomon; Meyer, Anne S

    2011-02-28

    Corn bran is mainly made up of the pericarp of corn kernels and is a byproduct stream resulting from the wet milling step in corn starch processing. Through statistic modeling this study examined the optimization of pretreatment of corn bran for enzymatic hydrolysis. A low pH pretreatment (pH 2, 150 °C, 65 min) boosted the enzymatic release of xylose and glucose and maximized biomass solubilization. With more acidic pretreatment followed by enzymatic hydrolysis the total xylose release was maximized (at pH 1.3) reaching ∼ 50% by weight of the original amount present in destarched corn bran, but the enzyme catalyzed xylose release was maximal after pretreatment at approx. pH 2. The total glucose release peaked after pretreatment of approx. pH 1.5 with an enzymatic release of approx. 68% by weight of the original amounts present in destarched corn bran. For arabinose the enzymatic release was negatively affected by the acidic pretreatment as labile arabinosyl-linkages were presumably hydrolysed directly during the pretreatment. A maximum of 60% arabinose release was achieved directly from the optimal (acidic) pretreatment. The total content of diferulic acids, supposedly involved in the cross-linking of the arabinoxylan polymers, decreased by both alkaline and acidic pretreatment pH, with the loss by alkaline pretreatments being highest. No direct correlation between the enzymatic release of xylose and the content of diferulic acids in the substrate could be verified. On the contrary the enzymatic release of xylose was significantly correlated to the total release of arabinose, indicating that the degree of arabinosyl-substitutions on the xylan backbone is an essential parameter for enzymatic hydrolysis of corn bran arabinoxylan. Copyright © 2010 Elsevier B.V. All rights reserved.

  10. Ordinance of 28 November 1983 on protection in case of emergencies in the neighbourhood of nuclear installations

    International Nuclear Information System (INIS)

    1983-01-01

    This Ordinance (RS 732.23) lays down the measures to be taken to assure the security of the population neighbouring nuclear installations. It defines the tasks of the nuclear operator, the Federal services as well as those of the Cantons and Communes. The Ordinance fixes the exact allocation of the costs of the emergency organisation and alarm system. The Ordinance entered into effect on 1 January 1984. (NEA) [fr

  11. On three-dimensional incompressible Navier-Stokes fluid on cantor sets in spherical Cantor type co-ordinate system

    Directory of Open Access Journals (Sweden)

    Meng Zhi-Jun

    2016-01-01

    Full Text Available This paper addresses the systems of the incompressible Navier-Stokes equations on Cantor sets without the external force involving the fractal heat-conduction problem vial local fractional derivative. The spherical Cantor type co-ordinate method is used to transfer the incompressible Navier-Stokes equation from the Cantorian co-ordinate system into the spherical Cantor type co-ordinate system.

  12. Food marketing to children through toys: response of restaurants to the first U.S. toy ordinance.

    Science.gov (United States)

    Otten, Jennifer J; Hekler, Eric B; Krukowski, Rebecca A; Buman, Matthew P; Saelens, Brian E; Gardner, Christopher D; King, Abby C

    2012-01-01

    On August 9, 2010, Santa Clara County CA became the first U.S. jurisdiction to implement an ordinance that prohibits the distribution of toys and other incentives to children in conjunction with meals, foods, or beverages that do not meet minimal nutritional criteria. Restaurants had many different options for complying with this ordinance, such as introducing more healthful menu options, reformulating current menu items, or changing marketing or toy distribution practices. To assess how ordinance-affected restaurants changed their child menus, marketing, and toy distribution practices relative to non-affected restaurants. Children's menu items and child-directed marketing and toy distribution practices were examined before and at two time points after ordinance implementation (from July through November 2010) at ordinance-affected fast-food restaurants compared with demographically matched unaffected same-chain restaurants using the Children's Menu Assessment tool. Affected restaurants showed a 2.8- to 3.4-fold improvement in Children's Menu Assessment scores from pre- to post-ordinance with minimal changes at unaffected restaurants. Response to the ordinance varied by restaurant. Improvements were seen in on-site nutritional guidance; promotion of healthy meals, beverages, and side items; and toy marketing and distribution activities. The ordinance appears to have positively influenced marketing of healthful menu items and toys as well as toy distribution practices at ordinance-affected restaurants, but did not affect the number of healthful food items offered. Copyright © 2012 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.

  13. Integrated analysis of hydrothermal flow through pretreatment

    Directory of Open Access Journals (Sweden)

    Archambault-Leger Veronique

    2012-07-01

    Full Text Available Abstract Background The impact of hydrothermal flowthrough (FT pretreatment severity on pretreatment and solubilization performance metrics was evaluated for three milled feedstocks (corn stover, bagasse, and poplar and two conversion systems (simultaneous saccharification and fermentation using yeast and fungal cellulase, and fermentation by Clostridium thermocellum. Results Compared to batch pretreatment, FT pretreatment consistently resulted in higher XMG recovery, higher removal of non-carbohydrate carbon and higher glucan solubilization by simultaneous saccharification and fermentation (SSF. XMG recovery was above 90% for FT pretreatment below 4.1 severity but decreased at higher severities, particularly for bagasse. Removal of non-carbohydrate carbon during FT pretreatment increased from 65% at low severity to 80% at high severity for corn stover, and from 40% to 70% for bagasse and poplar. Solids obtained by FT pretreatment were amenable to high conversion for all of the feedstocks and conversion systems examined. The optimal time and temperature for FT pretreatment on poplar were found to be 16 min and 210°C. At these conditions, SSF glucan conversion was about 85%, 94% of the XMG was removed, and 62% of the non carbohydrate mass was solubilized. Solubilization of FT-pretreated poplar was compared for C. thermocellum fermentation (10% inoculum, and for yeast-fungal cellulase SSF (5% inoculum, cellulase loading of 5 and 10 FPU/g glucan supplemented with β-glucosidase at 15 and 30 U/g glucan. Under the conditions tested, which featured low solids concentration, C. thermocellum fermentation achieved faster rates and more complete conversion of FT-pretreated poplar than did SSF. Compared to SSF, solubilization by C. thermocellum was 30% higher after 4 days, and was over twice as fast on ball-milled FT-pretreated poplar. Conclusions XMG removal trends were similar between feedstocks whereas glucan conversion trends were significantly

  14. Overcoming a powerful tobacco lobby in enacting local smoking ordinances: the Contra Costa County experience.

    Science.gov (United States)

    Ellis, G A; Hobart, R L; Reed, D F

    1996-01-01

    As part of a comprehensive tobacco education campaign, local health departments throughout California have been engaged in the process of enacting local clean indoor air ordinances to protect the public from the effects of secondhand smoke. This paper describes how a Northern California Bay Area health department worked with city and county governments to pass ordinances in the face of persistent tobacco industry opposition. The key strategies used by the health department included organizing broad-based coalitions, achieving effective use of the media, and educating the business community. Tobacco industry tactics included establishing local front groups that launched a massive misinformation campaign to frighten local businesses into believing that passage of an ordinance would adversely affect their business. Finally, the authors discuss how the tobacco industry has created a climate through state and national legislative activity to undermine the ability of local health departments to pursue effective tobacco control policies, most notably through preemptive legislation.

  15. Perbandingan Analisis Diskriminan dan Analisis Regresi Logistik Ordinal dalam Prediksi Klasifikasi Kondisi Kesehatan Bank

    Directory of Open Access Journals (Sweden)

    Fajri Zufa

    2017-12-01

    Full Text Available The purpose of this research is to compare the accuracy of bank classification prediction based on Capital Adequacy Ratio (CAR, Earning Asset Quality (EAQ, Non Performing Loan (NPL, Return on Assets (ROA, Net Interest Margin (NIM, Short Term Mismatch (STM and Loan to Deposit Ratio (LDR. Discriminant analysis and ordinal logistic regression analysis are compared in classifying the prediction. The data used are secondary data, namely data classification of bank conditions in Indonesia in 2014 obtained from research institute PT Infovesta Utama. Based on Apparent Error Rate (APER score obtained, it can be said that discriminant analysis is better in predicting the classification of bank conditions in Indonesia than that of ordinal logistic regression analysis. Discriminant analysis has the average prediction accuracy of 80%, while ordinal logistic regression analysis has the average prediction accuracy of 74,38%.

  16. Discrete Ordinates Method-Like Computation with Group Condensation and Angle Collapsing in Transport Theory

    International Nuclear Information System (INIS)

    Won, Jong Hyuck; Cho, Nam Zin

    2010-01-01

    In group condensation for transport method, it is well-known that angle-dependent total cross section is generated. To remove this difficulty on angledependent total cross section, we normally perform the group condensation on total cross section by using scalar flux weight as used in neutron diffusion method. In this study, angle-dependent total cross section is directly applied to the discrete ordinates method. In addition, angle collapsing concept is introduced based on equivalence to reduce calculational burden of transport computation. We also show numerical results for a heterogeneous 1-D slab problem with local/global iteration, in which fine-group discrete ordinates calculation is used in local problem while few-group angle collapsed discrete ordinates calculation is used in global problem iteratively

  17. Co-ordinating innate and adaptive immunity to viral infection: mobility is the key

    DEFF Research Database (Denmark)

    Wern, Jeanette Erbo; Thomsen, Allan Randrup

    2009-01-01

    the very essence of immune system physiology, a key to a rapid, efficient and optimally regulated immune response is the ability of the involved cells to rapidly shift between a stationary and a mobile state, combined with stringent regulation of cell migration during the mobile state. Through the co-ordinated......The host counters a viral infection through a complex response made up of components belonging to both the innate and the adaptive immune system. In this report, we review the mechanisms underlying this response, how it is induced and how it is co-ordinated. As cell-cell communication represents...... in mounting an efficient host response and co-ordinating innate and adaptive immunity during a primary viral infection....

  18. Actinides in silicate glasses and melts and on mineral surfaces: information on local co-ordination environments from XAFS spectroscopy and bond valence theory

    International Nuclear Information System (INIS)

    Brown, G.E.Jr.; Farges, F.; Brown, G.E.Jr.; Farges, F.; Bargar, J.R.; Farges, F.; Thomson Berbeco, H.

    2002-01-01

    The impact of actinides on the environment is mitigated by their interaction with particle surfaces and by incorporation into suitable waste forms. In both cases, a fundamental knowledge of the local co-ordination environment of actinide ions is essential for understanding their stability in various near-surface environments under a range of conditions. When actinide ions are sorbed on mineral surfaces, the extent to which the ions are immobilised depends on the type of surface complex or solid precipitate that forms. When incorporated into a glass or crystalline waste form, the stability of the actinide will depend in part on its redox state and local co-ordination environment. In both cases, XAFS spectroscopy can provide unique information on the number and types of first and, in certain cases, more distant neighbours, and their geometric arrangement (including inter-atomic distances and a measure of their disorder). When this structural information from XAFS spectroscopy is combined with Pauling bond valence theory and modem bond valences corrected for bond length variations, it is also possible to develop plausible models for their medium-range co-ordination environments (out to ≅ 4 Angstrom radial distance around the actinide) for both sorbed actinide ions and those present in a silicate glass or melt. We discuss results from several XAFS studies of the naturally occurring actinides uranium and thorium in sorption samples, silicate glasses and silicate melts at high temperature. (authors)

  19. Carbonyltrichlorotris(dimethylphenylphosphine)technetium-ethanol (1/1), the first seven-co-ordinate complex of technetium; position of this molecule in the Csub(3v) family

    International Nuclear Information System (INIS)

    Bandoli, G.; Clemente, D.A.; Mazzi, U.

    1978-01-01

    The preparation and the crystals and molecular structure of the title complex are reported. The co-ordination polyhedron is that of a distorted capped octahedron Csub(3v) symmetry). The technetium atom is seven-co-ordinate and bonded to three phosphine ligands (capped face), three chlorine ligands (uncapped face), and to the carbonyl group, which occupies the unique capping position. Crystals are monoclinic, space group P2 1 /c, with cell dimensions a = 11.732(9), b = 11.807(9), c = 23.588(12) A, and β103.42(8) 0 . The structure has been refined by least squares to a conventional R of 0.093 for 1 794 observed reflections. Metal-ligand bond lengths are: Tc-CO 1.86(2), Tc-C1 2.48(1). and Tc-p 2.44(1) A. Seven co-ordinate complexes are briefly reviewed: in particular, a description of Csub(3v) symmetry and its distortions has been developed in terms of repulsion theory and the angular-overlap model. (author9

  20. A multi-layer discrete-ordinate method for vector radiative transfer in a vertically-inhomogeneous, emitting and scattering atmosphere. I - Theory. II - Application

    Science.gov (United States)

    Weng, Fuzhong

    1992-01-01

    A theory is developed for discretizing the vector integro-differential radiative transfer equation including both solar and thermal radiation. A complete solution and boundary equations are obtained using the discrete-ordinate method. An efficient numerical procedure is presented for calculating the phase matrix and achieving computational stability. With natural light used as a beam source, the Stokes parameters from the model proposed here are compared with the analytical solutions of Chandrasekhar (1960) for a Rayleigh scattering atmosphere. The model is then applied to microwave frequencies with a thermal source, and the brightness temperatures are compared with those from Stamnes'(1988) radiative transfer model.

  1. DOGS: a collection of graphics for support of discrete ordinates codes

    International Nuclear Information System (INIS)

    Ingersoll, D.T.; Slater, C.O.

    1980-03-01

    A collection of computer codes called DOGS (Discrete Ordinates Graphics Support) has been developed to assist in the display and presentation of data generated by commonly used discrete ordinates transport codes. The DOGS codes include: EGAD for plotting two-dimensional geometries, ISOPLOT4 for plotting 2-D fluxes in a contour line fashion, FORM for plotting 2-D fluxes in a 3-D surface fashion, ACTUAL for calculating 2-D activities, TOOTH for calculating and plotting space-energy contributon fluxes, and ASPECT for plotting energy spectra. All of the codes use FIDO input formats and DISSPLA graphics software including the DISSPOP post processors

  2. First and second collision source for mitigating ray effects in discrete ordinate calculations

    International Nuclear Information System (INIS)

    Gomes, L.T.; Stevens, P.N.

    1991-01-01

    This work revisits the problem of ray effects in discrete ordinates calculations that frequently occurs in two- and three-dimensional systems which contain isolated sources within a highly absorbing medium. The effectiveness of using a first collision source or a second collision source are analyzed as possible remedies to mitigate this problem. The first collision and second collision sources are generated by three-dimensional Monte Carlo calculations that enables its application to a variety of source configurations, and the results can be coupled to a two- or three-dimensional discrete ordinates transport code. (author)

  3. Effect of ultrasound pre-treatment on the drying kinetics of brown seaweed Ascophyllum nodosum.

    Science.gov (United States)

    Kadam, Shekhar U; Tiwari, Brijesh K; O'Donnell, Colm P

    2015-03-01

    The effect of ultrasound pre-treatment on the drying kinetics of brown seaweed Ascophyllum nodosum under hot-air convective drying was investigated. Pretreatments were carried out at ultrasound intensity levels ranging from 7.00 to 75.78 Wcm(-2) for 10 min using an ultrasonic probe system. It was observed that ultrasound pre-treatments reduced the drying time required. The shortest drying times were obtained from samples pre-treated at 75.78 Wcm(-2). The fit quality of 6 thin-layer drying models was also evaluated using the determination of coefficient (R(2)), root means square error (RMSE), AIC (Akaike information criterion) and BIC (Bayesian information criterion). Drying kinetics were modelled using the Newton, Henderson and Pabis, Page, Wang and Singh, Midilli et al. and Weibull models. The Newton, Wang and Singh, and Midilli et al. models showed the best fit to the experimental drying data. Color of ultrasound pretreated dried seaweed samples were lighter compared to control samples. It was concluded that ultrasound pretreatment can be effectively used to reduce the energy cost and drying time for drying of A. nodosum. Copyright © 2014 Elsevier B.V. All rights reserved.

  4. Understanding Ionic Liquid Pretreatment of Lignocellulosic Biomasses

    Science.gov (United States)

    Pretreatment of biomass is essential for breaking apart highly ordered and crystalline plant cell walls and loosening the lignin and hemicellulose conjugation to cellulose microfibrills, thereby facilitating enzyme accessibility and adsorption and reducing costs of downstream saccharification proces...

  5. Extrusion Pretreatment of Lignocellulosic Biomass: A Review

    Directory of Open Access Journals (Sweden)

    Jun Zheng

    2014-10-01

    Full Text Available Bioconversion of lignocellulosic biomass to bioethanol has shown environmental, economic and energetic advantages in comparison to bioethanol produced from sugar or starch. However, the pretreatment process for increasing the enzymatic accessibility and improving the digestibility of cellulose is hindered by many physical-chemical, structural and compositional factors, which make these materials difficult to be used as feedstocks for ethanol production. A wide range of pretreatment methods has been developed to alter or remove structural and compositional impediments to (enzymatic hydrolysis over the last few decades; however, only a few of them can be used at commercial scale due to economic feasibility. This paper will give an overview of extrusion pretreatment for bioethanol production with a special focus on twin-screw extruders. An economic assessment of this pretreatment is also discussed to determine its feasibility for future industrial cellulosic ethanol plant designs.

  6. Hydrolysis of alkaline pretreated banana peel

    Science.gov (United States)

    Fatmawati, A.; Gunawan, K. Y.; Hadiwijaya, F. A.

    2017-11-01

    Banana peel is one of food wastes that are rich in carbohydrate. This shows its potential as fermentation substrate including bio-ethanol. This paper presented banana peel alkaline pretreatment and enzymatic hydrolysis. The pretreatment was intended to prepare banana peel in order to increase hydrolysis performance. The alkaline pretreatment used 10, 20, and 30% w/v NaOH solution and was done at 60, 70 and 80°C for 1 hour. The hydrolysis reaction was conducted using two commercial cellulose enzymes. The reaction time was varied for 3, 5, and 7 days. The best condition for pretreatment process was one conducted using 30% NaOH solution and at 80°C. This condition resulted in cellulose content of 90.27% and acid insoluble lignin content of 2.88%. Seven-day hydrolysis time had exhibited the highest reducing sugar concentration, which was7.2869 g/L.

  7. Mild-temperature dilute acid pretreatment for integration of first and second generation ethanol processes.

    Science.gov (United States)

    Nair, Ramkumar B; Kalif, Mahdi; Ferreira, Jorge A; Taherzadeh, Mohammad J; Lennartsson, Patrik R

    2017-12-01

    The use of hot-water (100°C) from the 1st generation ethanol plants for mild-temperature lignocellulose pretreatment can possibly cut down the operational (energy) cost of 2nd generation ethanol process, in an integrated model. Dilute-sulfuric and -phosphoric acid pretreatment at 100°C was carried out for wheat bran and whole-stillage fibers. Pretreatment time and acid type influenced the release of sugars from wheat bran, while acid-concentration was found significant for whole-stillage fibers. Pretreatment led up-to 300% improvement in the glucose yield compared to only-enzymatically treated substrates. The pretreated substrates were 191-344% and 115-300% richer in lignin and glucan, respectively. Fermentation using Neurospora intermedia, showed 81% and 91% ethanol yields from wheat bran and stillage-fibers, respectively. Sawdust proved to be a highly recalcitrant substrate for mild-temperature pretreatment with only 22% glucose yield. Both wheat bran and whole-stillage are potential substrates for pretreatment using waste heat from the 1st generation process for 2nd generation ethanol. Copyright © 2017 Elsevier Ltd. All rights reserved.

  8. Optimization of twin gear-based pretreatment of rice straw for bioethanol production

    International Nuclear Information System (INIS)

    Ahmed, Muhammad Ajaz; Rehman, Muhammd Saif Ur; Terán-Hilares, Ruly; Khalid, Saira; Han, Jong-In

    2017-01-01

    Highlights: • Twin gear reactor is a continuous high solids pretreatment reactor. • RSM was applied to optimize twin gear pretreatment for enzymatic digestibility. • 89% enzymatic digestibility was achieved under optimum conditions. • Thermomechanical pretreatment altered the structural features of rice straw. - Abstract: A laboratory twin-gear reactor (TGR) was investigated as a new means for the pretreatment of high solid lignocelluloses. Response surface methodology based on Box Behnken Design was used to optimize the enzymatic digestibility with respect to the pretreatment process variables: temperature of 50–90 °C, NaOH concentration of 2–6% and no. of cycles of 30–60. The results revealed that the TGR-based pretreatment led to the significant structural alterations through increases in pore size, pore volume, cellulose crystallinity and surface area. SEM images also confirmed the surface modifications in the pretreated rice straw. A response surface quadratic model predicted 90% of the enzymatic digestibility, and it was confirmed experimentally and through the analysis of variance (ANOVA) as well. The TGR extrusion proved to be an effective means for exceedingly high solids lignocellulose.

  9. Ultrasonic sludge pretreatment under pressure.

    Science.gov (United States)

    Le, Ngoc Tuan; Julcour-Lebigue, Carine; Delmas, Henri

    2013-09-01

    The objective of this work was to optimize the ultrasound (US) pretreatment of sludge. Three types of sewage sludge were examined: mixed, secondary and secondary after partial methanisation ("digested" sludge). Thereby, several main process parameters were varied separately or simultaneously: stirrer speed, total solid content of sludge (TS), thermal operating conditions (adiabatic vs. isothermal), ultrasonic power input (PUS), specific energy input (ES), and for the first time external pressure. This parametric study was mainly performed for the mixed sludge. Five different TS concentrations of sludge (12-36 g/L) were tested for different values of ES (7000-75,000 kJ/kgTS) and 28 g/L was found as the optimum value according to the solubilized chemical oxygen demand in the liquid phase (SCOD). PUS of 75-150 W was investigated under controlled temperature and the "high power input - short duration" procedure was the most effective at a given ES. The temperature increase in adiabatic US application significantly improved SCOD compared to isothermal conditions. With PUS of 150 W, the effect of external pressure was investigated in the range of 1-16 bar under isothermal and adiabatic conditions for two types of sludge: an optimum pressure of about 2 bar was found regardless of temperature conditions and ES values. Under isothermal conditions, the resulting improvement of sludge disintegration efficacy as compared to atmospheric pressure was by 22-67% and 26-37% for mixed and secondary sludge, respectively. Besides, mean particle diameter (D[4,3]) of the three sludge types decreased respectively from 408, 117, and 110 μm to about 94-97, 37-42, and 36-40 μm regardless of sonication conditions, and the size reduction process was much faster than COD extraction. Copyright © 2013 Elsevier B.V. All rights reserved.

  10. Pretreatment techniques for biofuels and biorefineries

    Energy Technology Data Exchange (ETDEWEB)

    Fang, Zhen (ed.) [Chinese Academy of Sciences, Kunming, YN (China). Xishuangbanna Tropical Botonical Garden

    2013-02-01

    The first book focused on pretreatment techniques for biofuels contributed by the world's leading experts. Extensively covers the different types of biomass, various pretreatment approaches and methods that show the subsequent production of biofuels and chemicals. In addition to traditional pretreatment methods, novel techniques are also introduced and discussed. An accessible reference work for students, researchers, academicians and industrialists in biorefineries. This book includes 19 chapters contributed by the world's leading experts on pretreatment methods for biomass. It extensively covers the different types of biomass (e.g. molasses, sugar beet pulp, cheese whey, sugarcane residues, palm waste, vegetable oil, straws, stalks and wood), various pretreatment approaches (e.g. physical, thermal, chemical, physicochemical and biological) and methods that show the subsequent production of biofuels and chemicals such as sugars, ethanol, extracellular polysaccharides, biodiesel, gas and oil. In addition to traditional methods such as steam, hot-water, hydrothermal, diluted-acid, organosolv, ozonolysis, sulfite, milling, fungal and bacterial, microwave, ultrasonic, plasma, torrefaction, pelletization, gasification (including biogas) and liquefaction pretreatments, it also introduces and discusses novel techniques such as nano and solid catalysts, organic electrolyte solutions and ionic liquids. This book offers a review of state-of-the-art research and provides guidance for the future paths of developing pretreatment techniques of biomass for biofuels, especially in the fields of biotechnology, microbiology, chemistry, materials science and engineering. It intends to provide a systematic introduction of pretreatment techniques. It is an accessible reference work for students, researchers, academicians and industrialists in biorefineries.

  11. Quantitative predictions of bioconversion of aspen by dilute acid and SPORL pretreatments using a unified combined hydrolysis factor (CHF)

    Science.gov (United States)

    W. Zhu; Carl J. Houtman; J.Y. Zhu; Roland Gleisner; K.F. Chen

    2012-01-01

    A combined hydrolysis factor (CHF) was developed to predict xylan hydrolysis during pretreatments of native aspen (Populus tremuloides) wood chips. A natural extension of previously developed kinetic models allowed us to account for the effect of catalysts by dilute acid and two sulfite pretreatments at different pH values....

  12. Enzymatic Pre-Treatment Increases the Protein Bioaccessibility and Extractability in Dulse (Palmaria palmata

    Directory of Open Access Journals (Sweden)

    Hanne K. Mæhre

    2016-10-01

    Full Text Available Several common protein extraction protocols have been applied on seaweeds, but extraction yields have been limited. The aims of this study were to further develop and optimize existing extraction protocols and to examine the effect of enzymatic pre-treatment on bioaccessibility and extractability of seaweed proteins. Enzymatic pre-treatment of seaweed samples resulted in a three-fold increase in amino acids available for extraction. Combining enzymatic pre-treatment with alkaline extraction resulted in a 1.6-fold increase in the protein extraction yield compared to a standard alkaline extraction protocol. A simulated in vitro gastrointestinal digestion model showed that enzymatic pre-treatment of seaweed increased the amount of amino acids available for intestinal absorption 3.2-fold. In conclusion, enzymatic pre-treatment of seaweeds is effective for increasing the amount of amino acids available for utilization and may thus be an effective means for increasing the utilization potential of seaweed proteins. However, both the enzymatic pre-treatment protocol and the protein extraction protocol need further optimization in order to obtain optimal cost-benefit and results from the in vitro gastrointestinal digestion model need to be confirmed in clinical models.

  13. Enzymatic Pre-Treatment Increases the Protein Bioaccessibility and Extractability in Dulse (Palmaria palmata).

    Science.gov (United States)

    Mæhre, Hanne K; Jensen, Ida-Johanne; Eilertsen, Karl-Erik

    2016-10-26

    Several common protein extraction protocols have been applied on seaweeds, but extraction yields have been limited. The aims of this study were to further develop and optimize existing extraction protocols and to examine the effect of enzymatic pre-treatment on bioaccessibility and extractability of seaweed proteins. Enzymatic pre-treatment of seaweed samples resulted in a three-fold increase in amino acids available for extraction. Combining enzymatic pre-treatment with alkaline extraction resulted in a 1.6-fold increase in the protein extraction yield compared to a standard alkaline extraction protocol. A simulated in vitro gastrointestinal digestion model showed that enzymatic pre-treatment of seaweed increased the amount of amino acids available for intestinal absorption 3.2-fold. In conclusion, enzymatic pre-treatment of seaweeds is effective for increasing the amount of amino acids available for utilization and may thus be an effective means for increasing the utilization potential of seaweed proteins. However, both the enzymatic pre-treatment protocol and the protein extraction protocol need further optimization in order to obtain optimal cost-benefit and results from the in vitro gastrointestinal digestion model need to be confirmed in clinical models.

  14. Dynamics of some forests in Kwa Zulu-Natal, South Africa, based on ordinations and size-class distributions

    CSIR Research Space (South Africa)

    Everard, DA

    1995-12-01

    Full Text Available . The authors have made lucid that ordinations between understorey and overstorey data form these plots would indicate the grain of a forest. Fine-grained forests would be indicated by close proximity, in ordination space, of understorey and overstoery...

  15. Ordinal logistic regression versus multiple binary logistic regression ...

    African Journals Online (AJOL)

    In this article, we modeled Higher Education Loans Board (HELB) loan application data from three public universities to determine whether the loan was ... It is expected that proper determination of the most accurate model will go a long way in minimizing the number of mis-classifications when awarding HELB loan.

  16. Ordinance on radioactive drugs or drugs treated with ionizing rays (AMRadV)

    International Nuclear Information System (INIS)

    1987-01-01

    The ordinance relates to the rules governing the marketing permit (approval) for, and prohibition of, radiosterilized and radioactive drugs (section 1 respectively section 2) according to section 7, subsection 1, of the Drugs Act. It applies also to dental filling materials and artificial denture materials. Excluded are finished drugs. (HP) [de

  17. On the Hadamard’s type inequalities for co-ordinated convex functions via fractional integrals

    Directory of Open Access Journals (Sweden)

    Abdullah Akkurt

    2017-07-01

    Full Text Available In this paper, we establish two identities for functions of two variables and apply them to give new Hermite–Hadamard type fractional integral inequalities for double fractional integrals involving functions whose derivatives are bounded or co-ordinates convex function on Δ≔[a,b]×[c,d] in R2 with a

  18. Radiation Protection Ordinance. Preventive Radiation Protection Act. 3. rev. and enlarged ed.

    International Nuclear Information System (INIS)

    Kramer, R.; Zerlett, G.

    1990-01-01

    This 3rd edition presents the official explanations of the legislative intent behind the Radiation Protection Ordinance of 1976 and the 2nd amending ordinance, and the commentaries which as usual refer to the legal aspects and the related medical, scientific, and technical aspects. As a consequence of the reactor accident at Chernobyl, the existing radiation protection law has been extended by the Act for Preventive Measures for Pretection of the Population Against the Hazards of Ionizing Radiation (Preventive Radiation Protection Act), establishing preventive legal provisions and measures, so that this new edition has likewise been extended by commentaries on the Protective Radiation Protection Act and an introduction to the new area of law. The material also includes the Act for Establishment of a Federal Office for Radiation Protection, of October 9, 1989, which amended the Atomic Energy Act and the Preventive Radiation Protection Act. The correction of the Radiation Protection Ordinance of October 16, 1989 (BGBl. I p. 1926) has been incorporated into the text of the amended version of the Radiation Protection Ordinance. Court decisions and literature referred to cover material published up to the first months of 1989. (orig.) [de

  19. 77 FR 39727 - Poarch Band of Creek Indians-Alcohol Beverage Control Ordinance

    Science.gov (United States)

    2012-07-05

    ... enforce all provisions of this Ordinance; (b) Deny issue, or restrict alcoholic beverage control renewal... of the total membership of the Tribal Council. All members of the Tribal Council do not need to be... shall be required to present any one of the following cards of identification which shows his or her...

  20. The Standards Agenda: Reflections of a Special Educational Needs Co-ordinator

    Science.gov (United States)

    Glazzard, Jonathan

    2014-01-01

    This study is a life history account of Bev, a special educational needs co-ordinator who works in a primary school in England. The research examines how, within Bev's experiences, the discourses of integration and inclusion have affected learners with special educational needs. Additionally, the study examines the impact of the…

  1. The midwives ordinance of Palestine, 1929: historical perspectives and current lessons.

    Science.gov (United States)

    Katvan, Eyal; Bartal, Nira

    2010-06-01

    Until 1929, midwifery in Palestine was relatively open to anyone and only partially regulated by the 1918 Public Health Ordinance, legislated shortly after the beginning of British rule. This article describes the factors that guided the shaping of midwifery and suggests possible sources of inspiration for the British legislator in crafting the Midwives Ordinance in 1929, including American, local (Jews and Arabs), and British ones. The Midwives Ordinance reflects the adjustment of midwifery to changes in the society that evolved under the British Mandate. The ordinance shows how the modern midwife's role contracted relative to the traditional one, in the context of social processes in other countries, east and west. This historical research project is based on interviews, archive documents and research literature. It analyzes the British interests in regulating midwifery, including the rationale of preserving public health and reducing infant mortality, against a background of political power struggles as well as cultural, social and professional diversity in Palestine (the tensions between the powers of doctors, nurses, and pharmacists).

  2. The impact of the 2002 Delaware smoking ordinance on heart attack and asthma.

    Science.gov (United States)

    Moraros, John; Bird, Yelena; Chen, Shande; Buckingham, Robert; Meltzer, Richard S; Prapasiri, Surasri; Solis, Luis H

    2010-12-01

    In the United States, smoking is the leading cause of death - having a mortality rate of approximately 435,000 people in 2000-accounting for 8.1% of all US deaths recorded that year. Consequently, we analyzed the Delaware Hospital Discharge Database, and identified state and non-state residents discharged with AMI or asthma for the years 1999 to 2004. Statistical data analysis compared the incidence of AMI or asthma for each group before (1999-2002) and after (2003-2004) the amendment. As a result, we found that pre-ordinance and post-ordinance quarterly rates of AMI for Delaware residents were 451 (se = 21) and 430 (se = 21) respectively, representing a 4.7% reduction. Over the same time period, there was negligible change in the incidence of AMI for non-Delaware residents. After adjusting for population growth, the Risk Ratio (RR) for asthma in Delaware residents post-ordinance was 0.95 (95% CI, 0.90 to 0.999), which represented a significant reduction (P = 0.046). By comparison, non-Delaware residents had an increased RR for asthma post-ordinance of 1.62 (95% CI, 1.46 to 1.86; P asthma in Delaware residents when compared to non-Delaware residents.

  3. 75 FR 62853 - Reno-Sparks Indian Colony Liquor Control Ordinance

    Science.gov (United States)

    2010-10-13

    ... will general millions of dollars in sales revenue and increase funding for essential government... introduction, possession, sale and consumption of liquor under Ordinance 14 (approved June 8, 1977) and Title 5... allow the Wal- Mart Superstore to open on RSIC lands, which will generate millions of dollars in sales...

  4. Feasibility of central co-ordinated EMA/CO for gestational trophoblastic disease in the Netherlands

    NARCIS (Netherlands)

    van der Houwen, Clasien; Rietbroek, Ron C.; Lok, Christianne A. R.; ten Kate-Booij, Marianne J.; Lammes, Frits B.; Ansink, Anca C.

    2004-01-01

    In the Netherlands, high risk gestational trophoblastic disease (GTD) patients are treated in different referral hospitals with a national working party on trophoblastic tumours having a co-ordinating function. Our purpose was to evaluate whether this policy is a satisfactory alternative to complete

  5. Supply chain co-ordination and industry clockspeed: an exploratory study

    NARCIS (Netherlands)

    Voordijk, Johannes T.; Akkermans, Henk; Meijboom, Bert

    2003-01-01

    The increasing velocity of change, or clockspeed, in the business environment is a key challenge for firms and industries nowadays. In this study, the impact of industry and organisation clockspeed on specific mechanisms used for supply chain co-ordination is investigated from an

  6. Collection of laws and ordinances concerning regulation of atomic energy, 1989 edition. 1989 ed.

    International Nuclear Information System (INIS)

    1989-01-01

    The collection of the laws and ordinances concerning the regulation of atomic energy, 1989 edition, was published by the Nuclear Safety Bureau, Science and Technology Agency. First, the abbreviated expressions of 56 laws and ordinances are shown. The contents are divided into Part 1: Fundamental laws and ordinances, Part 2: Regulation of nuclear source materials, nuclear fuel materials and nuclear reactors, Part 3: Prevention of radiation injuries due to radioactive isotopes and others, and Part 4: Related laws and ordinances. In Part 1, Atomic Energy Fundamental Act, Act of Institution of Atomic Energy Commission and Nuclear Safety Commission of Japan, Law Concerning the Technical Standard for Prevention of Radiation Injuries and 9 others are included. In Part 2, Law Concerning Regulation of Nuclear Source Materials, Nuclear Fuel Materials and Nuclear Reactors and 45 others are included. In Part 3, Law Concerning Prevention of Radiation Injuries Due to Radioisotopes and Others and 25 others are included. In Part 4, Electricity Enterprises Act, Road Transport and Vehicles Act, Ships' Safety Law, Labor Safety and Hygiene Law, Japan Atomic Energy Research Institute Law and 29 others are included. The contents are those as of November 30, 1988. (Kako, I.)

  7. Rigid Body Motion Calculated From Spatial Co-ordinates of Markers ...

    African Journals Online (AJOL)

    In this paper, we present a unified method for calculating spatial coordinates of markers for a rigid body motion such as in bones. Kinematical analysis of bone movement in cadaveric specimens or living objects had been developed. Here, we show how spatial co-ordinates of markers in or on bone can be calculated from ...

  8. On Constancy of Second Co-ordinate of the gonality sequence

    OpenAIRE

    Pal, Sarbeswar

    2017-01-01

    Let $X$ be a K3 surface and $L$ be an ample line bundle on it. In this article we will prove that under certain condition the second co-ordinate of the gonality sequence is constant along the smooth curves in the linear system $|L|$.

  9. Educating Leaders for Social Justice: The Case of Special Educational Needs Co-Ordinators

    Science.gov (United States)

    Liasidou, Anastasia; Svensson, Cathy

    2014-01-01

    In the light of policy imperatives to initiate and maintain inclusive education reforms, the role of special educational needs co-ordinators (SENCOs) in England and Wales should be reconceptualised with a view to their leading school reforms commensurate with the principles of an inclusive discourse. The article concentrates on the social justice…

  10. The added value of ordinal analysis in clinical trials: An example in traumatic brain injury

    NARCIS (Netherlands)

    B. Roozenbeek (Bob); P. Perel (Pablo); P. Edwards (Phil); I. Roberts (Ian); G.D. Murray (Gordon); A.I.R. Maas (Andrew); E.W. Steyerberg (Ewout)

    2011-01-01

    textabstractIntroduction: In clinical trials, ordinal outcome measures are often dichotomized into two categories. In traumatic brain injury (TBI) the 5-point Glasgow outcome scale (GOS) is collapsed into unfavourable versus favourable outcome. Simulation studies have shown that exploiting the

  11. The First Women’s ordination in the Episcopal Church of the 1970s

    Directory of Open Access Journals (Sweden)

    Posternak Andrei, priest

    2015-02-01

    Full Text Available Episcopal Church of the USA in 1976 adopted a positive resolution (1976-B300 regarding women’s ordination to the priesthood and episcopacy. The Church thus legalizes the experience of the Anglican community of the East coast: Philadelphia and Washington where in July 1974 and September 1975, took place women’s ordination. The article is devoted to the history of these ordinations, public reactions to them and theological discussions concerning the permissibility of female ordination in the Episcopal community of the first half of the 1970s. The research is based on the offi cial reports of the Episcopal Church. Believe in the Divine will on the vocation of women to the priesthood was associated with transformation of the Western society: women’s struggle for their rights and public struggle against race discrimination. The Anglican bishops were concerned about the problem of adaptation of the new ministry to modern conditions: the 1970s became a period of transition from traditional to post-Christian society in which gender was considered as a new social function. It will transform the Anglican community where the priesthood will become a form of ministry to the parish and in these conditions women can be ordained .

  12. Co-ordinated traffic control in freeway corridors : A proposed evaluation approach

    NARCIS (Netherlands)

    Hoogendoorn, S.P.; Bovy, P.H.L.; Van der Zijpp, N.J.

    1997-01-01

    In the course of the Telematics implications Programme Transport of the European Commission Fourth Framework Research Programme much attention is devoted to evaluation and demonstration. This report is part of the DACCORD project TR1017, devoted to the development and application of co-ordinated

  13. 77 FR 34975 - Seminole Nation of Oklahoma-Alcohol Control and Enforcement Ordinance

    Science.gov (United States)

    2012-06-12

    ... of Federal Law Federal law forbids the introduction, possession and sale of liquor in Indian Country... computing any period of time prescribed or allowed by this Ordinance, the day of the act, event, or default... so computed shall be included, unless it is a Saturday, a Sunday, or a legal holiday. For the...

  14. 76 FR 22913 - Alcoholic Beverage Control Ordinance of the Paiute Tribe of Utah

    Science.gov (United States)

    2011-04-25

    .... Federal law currently prohibits the introduction of liquor in Indian country (18 U.S.C. Sec. 1154), except... otherwise provided in this Ordinance, in computing the period of time prescribed or allowed by this... not be included. The last day of the period so computed shall be included, unless it is a Saturday...

  15. 78 FR 15037 - Bishop Paiute Tribe-Liquor Control Ordinance No. 2012-07

    Science.gov (United States)

    2013-03-08

    ... food, except in those areas classified by the California Department of Alcoholic Beverage Control as... service of liquor/ alcoholic beverage in a tribally licensed liquor/alcohol establishment if such person... beverages within the jurisdiction of the Bishop Paiute Tribe. This Ordinance will increase the ability of...

  16. Fair division under ordinal preferences: computing envy-free allocations of indivisible goods

    NARCIS (Netherlands)

    Bouveret, S.; Endriss, U.; Lang, J.; Coelho, H.; Studer, R.; Woolridge, M.

    2010-01-01

    We study the problem of fairly dividing a set of goods amongst a group of agents, when those agents have preferences that are ordinal relations over alternative bundles of goods (rather than utility functions) and when our knowledge of those preferences is incomplete. The incompleteness of the

  17. BALTORO a general purpose code for coupling discrete ordinates and Monte-Carlo radiation transport calculations

    International Nuclear Information System (INIS)

    Zazula, J.M.

    1983-01-01

    The general purpose code BALTORO was written for coupling the three-dimensional Monte-Carlo /MC/ with the one-dimensional Discrete Ordinates /DO/ radiation transport calculations. The quantity of a radiation-induced /neutrons or gamma-rays/ nuclear effect or the score from a radiation-yielding nuclear effect can be analysed in this way. (author)

  18. Multiple treatment comparisons in a series of anti-malarial trials with an ordinal primary outcome and repeated treatment evaluations

    Directory of Open Access Journals (Sweden)

    Youdom Solange

    2012-05-01

    Full Text Available Abstract Background Artemisinin-based combination therapies (ACT are widely used in African countries, including Cameroon. Between 2005 and 2007, five randomized studies comparing different treatment arms among artesunate-amodiaquine and other ACT were conducted in Cameroonian children aged two to 60 months who had uncomplicated Plasmodium falciparum malaria. In these studies, the categorical criterion proposed by the World Health Organization (WHO to assess the relative effectiveness of anti-malarial drugs was repeatedly evaluated on Days 14, 21 and 28 after treatment initiation. The aim of the present study was to compare the effects of different treatments on this repeated ordinal outcome, hence using the fully available information. Methods The quantitative synthesis was based on individual patient data. Due to the incomplete block design concerning treatment arms between different trials, a mixed treatment comparison (MTC meta-analysis approach was adopted. The repeated ordinal outcome was modelled through a latent variable, as a proportional odds mixed model with trial, period and treatment arms as covariates. The model was further complexified to account for the variance heterogeneity, and the individual log-residual variance was modelled as a linear mixed model, as well. The effects of individual covariates at inclusion, such as parasitaemia, fever, gender and weight, were also tested. Model parameters were estimated using a Bayesian approach via the WinBUGS software. After selecting the best model using Deviance Information Criterion (DIC, mixed treatment comparisons were based on the estimated treatment effects. Results Modeling the residual variance improved the model ability to adjust the data. The results showed that, compared to artesunate-amodiaquine (ASAQ, dihydroartemisinin-piperaquine (DHPP was significantly more efficacious. Artesunate-chlorproguanil-dapsone (ASCD was less efficacious than artesunate

  19. Simulated performance of reactor configurations for hot-water pretreatment of sugarcane bagasse.

    Science.gov (United States)

    Archambault-Léger, Véronique; Shao, Xiongjun; Lynd, Lee R

    2014-09-01

    During the pretreatment of cellulosic biomass for subsequent microbial or enzymatic processing, the fiber reactivity typically increases with increasing severity but so does sugar degradation. Experimental results with sugarcane bagasse show that this tradeoff can be mitigated substantially by pretreatment in a flow-through (FT) mode. A model that incorporates both kinetics and mass transfer was developed to simulate the performance of pretreatment in plug flow, counter-current flow, cross flow, discrete counter-current and partial FT configurations. The simulated results compare well to the literature for bagasse pretreated in both batch and FT configurations. A variety of FT configurations result in sugar degradation that is very low (1-5%) and 5-20-fold less than a conventional plug flow configuration. The performance exhibits strong sensitivity to the extent of hemicellulose solubilization, particularly for a conventional plug flow configuration. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  20. Mechanical pre-treatment for enzymatically enhanced energy efficient TMP; Mekanisk foerbehandling av flis foer effektiv enzymatisk paaverkan vid energieffektiv TMP tillverkning

    Energy Technology Data Exchange (ETDEWEB)

    Viforr, Silvia

    2008-11-15

    Thermomechanical pulp (TMP) processes are high energy demanding. This together with the high energy prices of nowadays results in significant costs, why less energy demanding processes are wished. This project has evaluated the potential for energy reductions in a TMP process by a mechanical pre-treatment of the wood chips combined with an enzymatic modification based on a cellulase mixture. The structure of the wood was opened up by the mechanical pre-treatment making it easier for the enzymes to penetrate into the pre-treated wood material. The enzymatic treatment was then run at optimum standard conditions. The EU project - Ecotarget 2004-2008 (www.ecotarget.com) have studied different types of enzymes that could be used for pre-treatment of wood chips in order to save energy during TMP processes. Based on these studies cellulose enzyme was recommended to be used at pre-treatment experiment performed by the Vaermeforsk project. Due to the fact that the Ecotarget-project has also been run during 2008 with activities involving enzymes, the steering board of the Vaermeforsk project took the decision to co-ordinate the experiments from both of the projects. This co-operation increased the funds and also the number of experiments for both of the projects. The experimental results from this project showed that energy reductions at a given tensile index could be achieved if gently mechanical pre-treated wood chips were enzymatically treated. An intensive mechanical pre-treatment gave negative effects on both fibre length and tear index while the light scattering coefficient was promoted, probably due to the fibre shortening. Enzymatic modification of mechanically pre-treated chips showed a favourable modification of the fibres, even regarding the fibre shortening, if compared to mechanical pre-treated chips only. The effects of cellulases was however not as expected, why a high amount of cellulases was used. Other types of enzymes which could attack the primary wall of

  1. Mechanism of melphalan crosslink enhancement by misonidazole pretreatment

    International Nuclear Information System (INIS)

    Taylor, Y.C.; Sawyer, J.M.; Hsu, B.; Brown, J.M.

    1984-01-01

    Sensitization of Chinese hamster ovary cells to melphalan (L-PAM) toxicity by prior treatment with misonidazole is associated with increased levels of DNA crosslinks believed to be the critical lesion for bifunctional alkylating agent toxicity. Enhanced L-PAM crosslinking of DNA could occur by a variety of mechanisms in MISO-pretreated cells including: (1) increased transport or binding of L-PAM, (2) decreased repair of L-PAM monoadducts which would allow more time for their conversion to crosslinks, (3) decreased crosslink repair (unhooking of one arm), or (4) chemical modification of the DNA structure, presumably by bound MISO derivatives, such that crosslink formation is facilitated. Previous studies have eliminated mechanisms (1) and (3). Mechanism (4) was investigated by following MISO-pretreatments of whole cells with L-PAM treatments of the isolated DNA from these cells. Treatment of bare DNA with L-PAM modeled very well the crosslinking behavior in whole cells although it was somewhat more efficient. In the presence of double stranded DNA and absence of repair systems during and after the L-PAM exposure, it was determined that MISO-pretreatments did not increase the crosslinking efficiency of L-PAM

  2. Rapid near infrared spectroscopy for prediction of enzymatic hydrolysis of corn bran after various pretreatments.

    Science.gov (United States)

    Baum, Andreas; Agger, Jane; Meyer, Anne S; Egebo, Max; Mikkelsen, Jørn Dalgaard

    2012-02-15

    Efficient generation of a fermentable hydrolysate is a primary requirement in the utilization of fibrous plant biomass as feedstocks in bioethanol processes. The first biomass conversion step usually involves a hydrothermal pretreatment before enzymatic hydrolysis. The purpose of the pretreatment step is to increase the responsivity of the substrate to enzymatic attack and the type of pretreatment affects the enzymatic conversion efficiency. Destarched corn bran is a fibrous, heteroxylan-rich side-stream from the starch industry which may be used as a feedstock for bioethanol production or as a source of xylose for other purposes. In the present study we demonstrate the use of diffuse reflectance near infrared spectroscopy (NIR) as a rapid and non-destructive analytical tool for evaluation of pretreatment effects on destarched corn bran. NIR was used to achieve classification between 43 differently pretreated corn bran samples using principal component analysis (PCA) and hierarchal clustering algorithms. Quantification of the enzymatically released monosaccharides by HPLC was used to design multivariate calibration models (biPLS) on the NIR spectra. The models could predict the enzymatic release of different levels of arabinose, xylose and glucose from all the differently pretreated destarched corn bran samples. The present study also demonstrates a generic, non-destructive solution to determine the enzymatic monosaccharide release from polymers in biomass side-streams, thereby potentially replacing the cumbersome HPLC analysis. Copyright © 2011 Elsevier B.V. All rights reserved.

  3. Enzymatic hydrolysis of pretreated soybean straw

    International Nuclear Information System (INIS)

    Xu Zhong; Wang Qunhui; Jiang Zhaohua; Yang Xuexin; Ji Yongzhen

    2007-01-01

    In order to produce lactic acid, from agricultural residues such as soybean straw, which is a raw material for biodegradable plastic production, it is necessary to decompose the soybean straw into soluble sugars. Enzymatic hydrolysis is one of the methods in common use, while pretreatment is the effective way to increase the hydrolysis rate. The optimal conditions of pretreatment using ammonia and enzymatic hydrolysis of soybean straw were determined. Compared with the untreated straw, cellulose in straw pretreated by ammonia liquor (10%) soaking for 24 h at room temperature increased 70.27%, whereas hemicellulose and lignin in pretreated straw decreased to 41.45% and 30.16%, respectively. The results of infrared spectra (IR), scanning electron microscope (SEM) and X-ray diffraction (XRD) analysis also showed that the structure and the surface of the straw were changed through pretreatment that is in favor of the following enzymatic hydrolysis. maximum enzymatic hydrolysis rate of 51.22% was achieved at a substrate concentration of 5% (w/v) at 50 deg. C and pH 4.8 using cellulase (50 fpu/g of substrate) for 36 h

  4. Some tools for the analysis of ordinal data

    African Journals Online (AJOL)

    'generalized linear model' (GLM) by NeIder & Wedderburn. (1972), and the subsequent flood of research in this area, should render this incorrect practice unnecessary. A very complete account of the theory concerned is to be found in. McCullagh & NeIder (1989) while Dobson (1990) provides a quick introduction to the ...

  5. A Thermodynamic Model for Predicting Phosphorus Partition between CaO-based Slags and Hot Metal during Hot Metal Dephosphorization Pretreatment Process Based on the Ion and Molecule Coexistence Theory

    Science.gov (United States)

    Yang, Xue-min; Li, Jin-yan; Chai, Guo-ming; Duan, Dong-ping; Zhang, Jian

    2016-08-01

    A thermodynamic model for predicting phosphorus partition L P between a CaO-based slags and hot metal during hot metal dephosphorization pretreatment process has been developed based on the ion and molecule coexistence theory (IMCT), i.e., the IMCT- L P model. The reaction abilities of structural units or ion couples in the CaO-based slags have been represented by the calculated mass action concentrations N i through the developed IMCT- N i model based on the IMCT. The developed IMCT- L P model has been verified to be valid through comparing with the measured L P as well as the predicted L P by two reported L P models from the literature. Besides the total phosphorus partition L P between the CaO-based slag and hot metal, the respective phosphorus partitions L P, i of nine dephosphorization products as P2O5, 3FeO·P2O5, 4FeO·P2O5, 2CaO·P2O5, 3CaO·P2O5, 4CaO·P2O5, 2MgO·P2O5, 3MgO·P2O5, and 3MnO·P2O5 can also be accurately predicted by the developed IMCT- L P model. The formed 3CaO·P2O5 accounts for 99.20 pct of dephosphorization products comparing with the generated 4CaO·P2O5 for 0.08 pct. The comprehensive effect of CaO+Fe t O, which can be described by the mass percentage ratio (pct Fe t O)/(pct CaO) or the mass action concentration ratio N_{Fe}t O/N_{Fe}t O N_{CaO}. N_{CaO}} as well as the mass percentage product (pct Fe t O) × (pct CaO) or the mass action concentration product N_{{{{Fe}}t {{O}}}}5 × N_{{CaO}}3 , controls dephosphorization ability of the CaO-based slags. A linear relationship of L P against (pct Fe t O)/(pct CaO) can be correlated compared with a parabolic relationship of L P against N_{Fe}t O/N_{Fe}t O N_{CaO}. N_{CaO}, while the linear relationship of L P against (pct Fe t O) × (pct CaO) or N_{Fe}t O5 × N_{CaO}3 can be established. Thus, the mass percentage product (pct Fe t O) × (pct CaO) and the mass action concentration product N_{Fe}t O5 × N_{CaO}3 are recommended to represent the comprehensive effect of CaO+Fe t O on

  6. Impact analysis of different chemical pre-treatments on colour of apple discs during drying process

    Directory of Open Access Journals (Sweden)

    Jasmina Lukinac

    2009-01-01

    Full Text Available The main purpose of this study was to compare colour changes of chemically pre-treated dried apple discs. Changes were observed by chromameter in L*a*b* colour model by using Minolta chromameter CR-400 and by image analysis system in RGB colour model. Apple discs variety "Gold Rush" were pre-treated and dried in laboratory tray drier at drying temperature 70 °C and at airflow velocity of 1.5 ms-1. Different chemical pre-treatments were applied on apple discs (dipping in 0.5% ascorbic acid solution; 0.3% L–cysteine solution; 0.1% 4–hexyl resorcinol solution and 1% sodium metabisulphite solution. Mean values of colour parameters, colour changes and correlation coefficients for apple discs were calculated for both colour models. The analysis showed statistically significant influence of pre-treatment method on total colour changes for both chosen colour models of dried apples. Calculated correlation coefficient between colour changes for used models was found to be 0.894. According to colour characteristics the best results were achieved when samples were pre-treated with 0.5% ascorbic acid solution. According to calculated results it was found that image analysis method as well as colorimetric method can be used to observe the colour changes on dried apple discs.

  7. Law 2006-26 of 9 August concerning the modification of ordinance 93-16 of 2 March 1993 concerning mining law completed by ordinance 99-48 of 5 November 1999

    International Nuclear Information System (INIS)

    2006-01-01

    This law precise that article 36 of ordinance 93-16 of 2 March 1993 concerning mining law and completed by ordinance 99-48 of 5 November is abrogated. Articles 2, 8, 24, 34, 35, 44, 49, 51, 63, 82, 83, 84, 85, 86, 87, 88, 92, 93, 94, 95, 96, 97, 99, 105, 136 and title X bis of ordinance 93-16 of 2 mach 1993 are modified or completely changed. The modification involves State ownership, government right, surface and validity of licence or lease, domain of mining law application, mining convention, closed/protected or prohibited zones, fiscal and custom duties [fr

  8. Microbial pretreatment of cotton stalks by Phanerochaete chrysosporium for bioethanol production

    Science.gov (United States)

    Shi, Jian

    .04% for SmC and SSC pretreated samples, respectively) compared with untreated cotton stalk samples (17.93%). Washing of pretreated cotton stalks alone caused no significant increase in cellulose conversion. However, a heat treatment (autoclaving) followed by washing remarkably improved (Penzyme production, and oxygen uptake associated with the growth of P. chrysosporium during 14 days fungal pretreatment were developed. For SmC pretreatment, model parameters were estimated by nonlinear regression and validated using an independent set of experimental data. Models yielded sufficiently accurate predictions for holocellulose consumption (R2=0.9772 and 0.9837, 1d and 3d oxygen flushing, respectively), lignin degradation (R2=0.9879 and 0.8682) and ligninolytic enzyme production (R2=0.8135 and 0.9693) under both 1 and 3d oxygen flushing conditions. However, the prediction capabilities for fungal growth (1d and 3d), cellulase production (3d) and oxygen uptake (3d) were limited. For SSC, the models were established in three phases (I: day 0-4, II: day 4-7, III: day 7-14). After validation it was shown that the developed models can yield sufficiently accurate predictions for fungal growth (R 2=0.9724), holocellulose consumption (R2=0.9686), lignin degradation (R2=0.9309) and ligninolytic enzyme production (R2=0.9203); however predictions of cellulase production were fair (R2=0.6133). Although significant delignification occurred during fungal pretreatment indicating the presence of ligninolytic enzymes, common spectrophotometric enzyme assays failed to detect lignin peroxidase (LiP) and manganese peroxidase (MnP) activities in fungal pretreatment cultures. Efforts were made to overcome the drawbacks of standardized assays by performing protein gel electrophoresis and crude enzyme delignification studies. Results from this research are expected to be beneficial in the development of pretreatment technologies that are environment friendly and utilize naturally occurring

  9. Identification of a cis-regulatory element by transient analysis of co-ordinately regulated genes

    Directory of Open Access Journals (Sweden)

    Allan Andrew C

    2008-07-01

    Full Text Available Abstract Background Transcription factors (TFs co-ordinately regulate target genes that are dispersed throughout the genome. This co-ordinate regulation is achieved, in part, through the interaction of transcription factors with conserved cis-regulatory motifs that are in close proximity to the target genes. While much is known about the families of transcription factors that regulate gene expression in plants, there are few well characterised cis-regulatory motifs. In Arabidopsis, over-expression of the MYB transcription factor PAP1 (PRODUCTION OF ANTHOCYANIN PIGMENT 1 leads to transgenic plants with elevated anthocyanin levels due to the co-ordinated up-regulation of genes in the anthocyanin biosynthetic pathway. In addition to the anthocyanin biosynthetic genes, there are a number of un-associated genes that also change in expression level. This may be a direct or indirect consequence of the over-expression of PAP1. Results Oligo array analysis of PAP1 over-expression Arabidopsis plants identified genes co-ordinately up-regulated in response to the elevated expression of this transcription factor. Transient assays on the promoter regions of 33 of these up-regulated genes identified eight promoter fragments that were transactivated by PAP1. Bioinformatic analysis on these promoters revealed a common cis-regulatory motif that we showed is required for PAP1 dependent transactivation. Conclusion Co-ordinated gene regulation by individual transcription factors is a complex collection of both direct and indirect effects. Transient transactivation assays provide a rapid method to identify direct target genes from indirect target genes. Bioinformatic analysis of the promoters of these direct target genes is able to locate motifs that are common to this sub-set of promoters, which is impossible to identify with the larger set of direct and indirect target genes. While this type of analysis does not prove a direct interaction between protein and DNA

  10. Cleanser, Detergent, Personal Care Product Pretreatment Evaluation

    Science.gov (United States)

    Adam, Niklas

    2010-01-01

    The purpose of the Cleanser, Detergent, Personal Care Product, and Pretreatment Evaluation & Selection task is to identify the optimal combination of personal hygiene products, crew activities, and pretreatment strategies to provide the crew with sustainable life support practices and a comfortable habitat. Minimal energy, mass, and crew time inputs are desired to recycle wastewater during long duration missions. This document will provide a brief background on the work this past year supporting the ELS Distillation Comparison Test, issues regarding use of the hygiene products originally chosen for the test, methods and results used to select alternative products, and lessons learned from testing.

  11. Trimetazidine As Cardioplegia Addictive Without Pre-treatment Does Not Improve Myocardial Protection: Study In A Swine Working Heart Model [trimetazidina Como Aditivo Em Solução Cardioplégica Sem Pré-tratamento Não Traz Proteção Adicional Ao Miocárdio Isquêmico: Estudo Em Modelo Suíno De Coração Isolado

    OpenAIRE

    Silveira Filho L.D.M.; Petrucci Jr. O.; Do Carmo M.R.; De Oliveira P.P.M.; Vilarinho K.A.S.; Vieira R.W.; Braile D.M.

    2008-01-01

    Objective: The aim of this study is to verify in an isolated working heart swine model if the acute administration of trimetazidine to cardioplegia, without pre=treatment improves heart performance. Methods: Eighteen pairs of swines were used in this working heart model, divided into three groups (n = 6) that underwent regional and global ischemia. Each group was selected to a different treatment: St Thomas cardioplegia (ST), St Thomas enriched with trimetazidine (TMZ) and control group (Co)....

  12. Improvement of methane production from waste paper by pretreatment with rumen fluid.

    Science.gov (United States)

    Baba, Yasunori; Tada, Chika; Fukuda, Yasuhiro; Nakai, Yutaka

    2013-01-01

    Cellulose hydrolysis is the rate-limiting step in anaerobic digestion. In the present study, waste paper was used as a model of cellulosic biomass and was pretreated with rumen fluid prior to methane production. To achieve a high methane yield, the reaction time of the pretreatment was examined. Waste paper was soaked with rumen fluid for 6 and 24h at 37 °C. Various volatile fatty acids, especially acetate, were produced by the pretreatment. Semicontinuous methane production was carried out over a 20-day period. The best daily methane yield was obtained by the 6-h pretreatment. The amount was 2.6 times higher than that of untreated paper, which resulted in 73.4% of the theoretical methane yield. During methane production, the cellulose, hemicellulose and lignin degradabilities were improved by the pretreatment. Pretreatment by rumen fluid is therefore a powerful method to accelerate the methane yield from a cellulosic biomass. Copyright © 2012 Elsevier Ltd. All rights reserved.

  13. Integration of fermentative biohydrogen with methanogenesis from fruit–vegetable waste using different pre-treatments

    International Nuclear Information System (INIS)

    Jia, Xuan; Li, Mingxiao; Xi, Beidou; Zhu, Chaowei; Yang, Yang; Xia, Tianming; Song, Caihong; Pan, Hongwei

    2014-01-01

    Highlights: • An optimal pre-treatment for FVW used in two-stage fermentation is presented. • The spectroscopic characteristics of soluble metabolites were analysed. • The effluents were characterised by EEM with a parallel factor analysis. - Abstract: Fruit–vegetable waste was subjected to three different pre-treatments to enrich the two-stage biofuel production potential. The fluorescence excitation–emission matrix (EEM) spectra coupled with parallel factor (PARAFAC) analysis and fluorescence regional integration analysis were utilised to investigate dissolved organic matter degradation during two-stage fermentation process. The results showed that compared with that of alkali and enzyme pre-treatments, the acid pre-treatment resulted in the maximum biogas production rates and proportion in the hydrogenogenic stage (10.11 mL/h, 41.2% hydrogen) when combined with the methanogenic process (4.67 mL/h, 76.1% methane). In addition, the analysis of soluble metabolites composition indicated that both ethanol- and butyric acid-type fermentation processes had taken place as a result of acid pre-treatment, whereas only butyric acid-type fermentation resulted from alkali and enzyme pre-treatments. The PARAFAC analysis modelling of the EEM spectra revealed three fluorescent components in the effluents of three fermentation stages and assumed that the projected characteristic value may be used as a rapidly obtained indicator for substrate degradation and system stability of a two-stage biofuel production process

  14. Comparison of different pretreatments for the production of bioethanol and biomethane from corn stover and switchgrass.

    Science.gov (United States)

    Papa, G; Rodriguez, S; George, A; Schievano, A; Orzi, V; Sale, K L; Singh, S; Adani, F; Simmons, B A

    2015-05-01

    In this study the efficiency of mild ionic liquid (IL) pretreatment and pressurized hot water (PHW) is evaluated and compared in terms of bioethanol and biomethane yields, with corn stover (CS) and switchgrass (SG) as model bioenergy crops. Both feedstocks pretreated with the IL 1-ethyl-3-methylimidazolium acetate [C2C1Im][OAc] at 100°C for 3h exhibited lower glucose yield that those treated with harsher pretreatment conditions previously used. Compared to PHW, IL pretreatment demonstrated higher bioethanol yields; moreover IL pretreatment enhanced biomethane production. Taking into consideration both bioethanol and biomethane productions, results indicated that when using IL pretreatment, the total energy produced per kg of total solids was higher compared to untreated biomasses. Specifically energy produced from CS and SG was +18.6% and +34.5% respectively, as compared to those obtained by hot water treatment, i.e. +2.3% and +23.4% for CS and SG, respectively. Copyright © 2015 Elsevier Ltd. All rights reserved.

  15. The historical development of Presbyterian ordination polity as background to the gay and lesbian ordination debate in the Presbyterian Church (U.S.A.

    Directory of Open Access Journals (Sweden)

    Roch� F. Vermaak

    2010-03-01

    Full Text Available The United Presbyterian Church in the U.S.A. and the Presbyterian Church in the U.S. united in 1983 to form the Presbyterian Church (U.S.A.. Since 1978, these three denominations have been involved in an ongoing debate regarding same-gender relationships. Subsequently, General Assemblies and General Assembly Permanent Judicial Commissions (GAPJC � the highest denominational court � have formed a polity regarding the election and ordination and/or installation of gays and lesbians as officers, i.e. deacons, elders, and ministers of the Word and Sacrament, as well as same-gender blessings and marriages. This first of three papers will focus on the historical development of Presbyterian ordination polity with emphasis on specific markers such as the Adopting Act of 1729 with its emphasis on scrupling and essentials, the five fundamentals of 1910 and the Special Commission of 1925 regarding subscription, G-6.0106b Book of Order, and relevant GAPJC rulings.

  16. Co-ordinated research project on comparative international studies of osteoporosis using isotope techniques. Report on the final research co-ordination meeting

    International Nuclear Information System (INIS)

    2002-01-01

    In 1994, the International Atomic Energy Agency started the five-year Co-ordinated Research Project (CRP) on Comparative International Studies of Osteoporosis Using Isotope Techniques. The objectives of this study were: To harmonize the techniques of measuring BMD within the participating countries and to obtain data that can be compared between the different study groups (countries); To determine whether early adult PBM varies between populations over the age range from 15 to 50 years. In other words, to determine the age of peak bone mass in selected populations from developing countries; To explore environmental and nutritional contributions to any determined differences. Further information about the purpose and scope of the CRP may be found in the report of the Advisory Group Meeting (AGM) held in 19921 and other reports of this CRP. The fourth Research Co-ordination Meeting (RCM) for participants of the CRP, which is the subject of the present report, was held at the University of Sheffield Medical School; WHO Collaborating Center for Metabolic Bone Diseases in Sheffield, UK from 28 Feb. to 3 March 2000

  17. Sugarcane bagasse pretreatment using three imidazolium-based ionic liquids; mass balances and enzyme kinetics

    Directory of Open Access Journals (Sweden)

    Karatzos Sergios

    2012-08-01

    Full Text Available Abstract Background Effective pretreatment is key to achieving high enzymatic saccharification efficiency in processing lignocellulosic biomass to fermentable sugars, biofuels and value-added products. Ionic liquids (ILs, still relatively new class of solvents, are attractive for biomass pretreatment because some demonstrate the rare ability to dissolve all components of lignocellulosic biomass including highly ordered (crystalline cellulose. In the present study, three ILs, 1-butyl-3-methylimidazolium chloride ([C4mim]Cl, 1-ethyl-3-methylimidazolium chloride ([C2mim]Cl, 1-ethyl-3-methylimidazolium acetate ([C2mim]OAc are used to dissolve/pretreat and fractionate sugarcane bagasse. In these IL-based pretreatments the biomass is completely or partially dissolved in ILs at temperatures greater than 130°C and then precipitated by the addition of an antisolvent to the IL biomass mixture. For the first time mass balances of IL-based pretreatments are reported. Such mass balances, along with kinetics data, can be used in process modelling and design. Results Lignin removals of 10% mass of lignin in bagasse with [C4mim]Cl, 50% mass with [C2mim]Cl and 60% mass with [C2mim]OAc, are achieved by limiting the amount of water added as antisolvent to 0.5 water:IL mass ratio thus minimising lignin precipitation. Enzyme saccharification (24 h, 15FPU yields (% cellulose mass in starting bagasse from the recovered solids rank as: [C2mim]OAc(83% > >[C2mim]Cl(53% = [C4mim]Cl(53%. Composition of [C2mim]OAc-treated solids such as low lignin, low acetyl group content and preservation of arabinosyl groups are characteristic of aqueous alkali pretreatments while those of chloride IL-treated solids resemble aqueous acid pretreatments. All ILs are fully recovered after use (100% mass as determined by ion chromatography. Conclusions In all three ILs regulated addition of water as an antisolvent effected a polysaccharide enriched precipitate since some of the lignin

  18. The use of the co-ordinate measuring machine for the study of three-dimensional biomechanics of the knee.

    Science.gov (United States)

    Veselko, M; Jenko, M; Lipuscek, I

    1998-07-01

    Original methodology for the study of three-dimensional biomechanics of the knee is presented in the paper. Defining the geometry of the rigid body in the body-fixed reference frame and the orientation of the body-fixed reference frame in the global co-ordinate system are the theoretic basis. The data in the form of co-ordinates of the Cartesian frame are gathered by the co-ordinate measuring machine and analysed by specially computer program. The theory and a practical example of the study of the three-dimensional biomechanics of the knee are presented. Various possibilities of the use of the methodology are discussed.

  19. Impact of pretreatment with dilute sulfuric acid under moderate temperature on hydrolysis of corn stover with two enzyme systems.

    Science.gov (United States)

    Tai, Chao; Keshwani, Deepak

    2014-03-01

    Pretreatment of corn stover with dilute sulfuric acid at moderate temperature was investigated, and glucan digestibility by Cellic CTec2 and Celluclast on the pretreated biomass was compared. Pretreatments were carried out from 60 to 180 min at the temperature from 105 to 135 °C, with acid concentrations ranging from 0.5 to 2% (w/v). Significant portion of xylan was removed during pretreatment, and the glucan digestibility by CTec2 was significantly better than that by Celluclast in all cases. Analysis showed that glucan digestibility by both two enzymes correlated directly with the extent of xylan removal in pretreatment. Confidence interval was built to give a more precise range of glucan conversion and to test the significant difference among pretreatment conditions. Response surface model was built to obtain the optimal pretreatment condition to achieve high glucan conversion after enzymatic hydrolysis. Considering the cost and energy savings, the optimal pretreatment condition of 1.75% acid for 160 min at 135 °C was determined, and glucan conversion can achieve the range from 72.86 to 76.69% at 95% confidence level after enzymatic hydrolysis, making total glucan recovery up to the range from 89.42 to 93.25%.

  20. Simulation of the ozone pretreatment of wheat straw.

    Science.gov (United States)

    Bhattarai, Sujala; Bottenus, Danny; Ivory, Cornelius F; Gao, Allan Haiming; Bule, Mahesh; Garcia-Perez, Manuel; Chen, Shulin

    2015-11-01

    Wheat straw is a potential feedstock in biorefinery for sugar production. However, the cellulose, which is the major source of sugar, is protected by lignin. Ozonolysis deconstructs the lignin and makes cellulose accessible to enzymatic digestion. In this study, the change in lignin concentration with different ozonolysis times (0, 1, 2, 3, 5, 7, 10, 15, 20, 30, 60min) was fit to two different kinetic models: one using the model developed by Garcia-Cubero et al. (2012) and another including an outer mass transfer barrier or "cuticle" region where ozone mass transport is reduced in proportion to the mass of unreacted insoluble lignin in the cuticle. The kinetic parameters of two mathematical models for predicting the soluble and insoluble lignin at different pretreatment time were determined. The results showed that parameters derived from the cuticle-based model provided a better fit to experimental results compared to a model without a cuticle layer. Copyright © 2015 Elsevier Ltd. All rights reserved.

  1. Radioactive whey concentrate - a case to apply section 3 of the Radiation Protection Ordinance

    International Nuclear Information System (INIS)

    Sauer, G.W.; Zypries, B.

    1988-01-01

    According to the authors, section 4 StrlSchV does not apply, the case has to be handled applying section 3 StrlSchV (Radiation Protection Ordinance). This means that the storage, treatment and disposal of the radioactive whey concentrate is subject to licensing. Disposal as radioactive waste, however, will require a licence only if the limit given in section 4 IV, No. 2 lit. e, the 10 -4 -fold of the allowed radioactivity per gramme (i.e. 3700 Bq/kg) is exceeded. The averaged radioactivity data measured do exceed this limit. Only the transport of the radioactive whey concentrate does not fall under the provisions of the ordinances on road transport or rail transport of hazardons substances, as the limit given there is 74 Bq/g of specific activity. (orig./HP) [de

  2. Gender discrimination may be worse than you think: testing ordinal interactions in power research.

    Science.gov (United States)

    Elias, Steven M; Cropanzano, Russell

    2006-04-01

    The authors reanalyze the data of a study by S. M. Elias and R. J. Loomis (2004), which aimed to determine how an instructor's gender may influence his or her ability to gain student compliance. S. M. Elias and R. J. Loomis observed few significant gender effects using traditional multivariate analyses of variance. The authors reanalyze this data using the more appropriate statistical techniques for detecting ordinal interactions recommended by M. J. Strube and P. Bobko (1989) and S. M. Elias (2004). An ordinal interaction occurs when 1 cell of a 2 x 2 design is responsible for a significant interaction (e.g., female instructors suffering only when rated by male students). Reanalysis of the data resulted in more robust findings.

  3. On the equivalence between the discrete ordinates and the spherical harmonics methods in radiative transfer

    International Nuclear Information System (INIS)

    Barichello, L.B.; Siewert, C.E.

    1998-01-01

    In this work concerning steady-state radiative-transfer calculations in plane-parallel media, the equivalence between the discrete ordinates method and the spherical harmonics method is proved. More specifically, it is shown that for standard radiative-transfer problems without the imposed restriction of azimuthal symmetry the two methods yield identical results for the radiation intensity when the quadrature scheme for the discrete ordinates method is defined by the zeros of the associated Legendre functions and when generalized Mark boundary conditions are used to define the spherical harmonics solution. It is also shown that, with these choices for a quadrature scheme and for the boundary conditions, the two methods can be formulated so as to require the same computational effort. Finally a justification for using the generalized Mark boundary conditions in the spherical harmonics solution is given

  4. Predictors of pretreatment CA125 at ovarian cancer diagnosis

    DEFF Research Database (Denmark)

    Babic, Ana; Cramer, Daniel W; Kelemen, Linda E

    2017-01-01

    in CA125 between studies and linear regression to estimate the association between epidemiologic factors and tumor characteristics and pretreatment CA125 levels. RESULTS: In age-adjusted models, older age, history of pregnancy, history of tubal ligation, family history of breast cancer, and family...... history of ovarian cancer were associated with higher CA125 levels while endometriosis was associated with lower CA125 levels. After adjusting for tumor-related characteristics (stage, histology, grade), body mass index (BMI) higher than 30 kg/m2was associated with 10% (95% CI 2, 19%) higher CA125 levels...

  5. Encouraging ethical considerations - One important task for a national co-ordinator for nuclear waste disposal

    International Nuclear Information System (INIS)

    Soederberg, O.

    1999-01-01

    The paper is a brief description of the role and tasks of the Swedish National Co-ordinator for Nuclear Waste Disposal with special regard to one of his activities encouraging ethical considerations in the nuclear waste management issue. Examples are given of ethical considerations which have emerged during discussions among representatives of municipalities which are affected by the current search for a site for a deep geological repository in Sweden for spent nuclear fuel

  6. Analytical Treatment of Higher-Order Graphs: A Path Ordinal Method for Solving Graphs

    Directory of Open Access Journals (Sweden)

    Hala Kamal

    2017-11-01

    Full Text Available Analytical treatment of the composition of higher-order graphs representing linear relations between variables is developed. A path formalism to deal with problems in graph theory is introduced. It is shown how paths in the composed graph representing individual contributions to variables relation can be enumerated and represented by ordinals. The method allows for one to extract partial information and gives an alternative to classical graph approach.

  7. Developing Local Emergency Management by Co-Ordination Between Municipalities in Policy Networks: Experiences from Sweden

    OpenAIRE

    Palm, Jenny; Ramsell, Elina

    2007-01-01

    This study aims to increase our understanding of how co-operation in inter-municipality policy networks in a Swedish region is established and maintained regarding emergency management. We discuss how a network of five municipalities emerged and took shape. Overall, we conclude that co-ordination and co-operation in municipal emergency management are probably relatively easy to develop, because it is easy for the involved actors to see the benefits. Sharing resources is seen as crucial when e...

  8. Ordinance of 5 December 1983 concerning funds for the decommissioning of nuclear installations

    International Nuclear Information System (INIS)

    1983-01-01

    This Ordinance (RS 732.013) which entered into force on 1 January 1984 establishes a fund for the financing of decommissioning activities which was provided for by the Federal Order of 1978 concerning the Atomic Energy Act. This fund is destined to finance these operations. Nuclear operators are obliged to make annual contributions which are calculated to cover the costs which each one of them expects to encounter at the time of decommissioning. (NEA) [fr

  9. Time lagged ordinal partition networks for capturing dynamics of continuous dynamical systems

    OpenAIRE

    McCullough, Michael; Small, Michael; Stemler, Thomas; Iu, Herbert Ho-Ching

    2015-01-01

    We investigate a generalised version of the recently proposed ordinal partition time series to network transformation algorithm. Firstly we introduce a fixed time lag for the elements of each partition that is selected using techniques from traditional time delay embedding. The resulting partitions define regions in the embedding phase space that are mapped to nodes in the network space. Edges are allocated between nodes based on temporal succession thus creating a Markov chain representation...

  10. Handbook for the planning, co-ordination and evaluation of emergency exercises in nuclear power plants

    International Nuclear Information System (INIS)

    Schmidtborn, I.; Bath, N.

    1999-01-01

    The efficiency of the on-site emergency organization in German nuclear power plants is tested regularly through emergency exercises. To achieve federal harmonization on a high level of quality a handbook for the planning, co-ordination and evaluation of such exercises has been developed in the frame of the regulatory investigation programme. In this handbook requirements are set out for emergency training. Key elements are a modular structure, rules to be observed and guidance for post-exercise evaluation. (orig.) [de

  11. Discrete ordinate solution of the radiative transfer equation in the 'polarization normal wave representation'

    Science.gov (United States)

    Kylling, A.

    1991-01-01

    The transfer equations for normal waves in finite, inhomogeneous and plane-parallel magnetoactive media are solved using the discrete ordinate method. The physical process of absorption, emission, and multiple scattering are accounted for, and the medium may be forced both at the top and bottom boundary by anisotropic radiation as well as by internal anisotropic sources. The computational procedure is numerically stable for arbitrarily large optical depths, and the computer time is independent of optical thickness.

  12. Gamma-Weighted Discrete Ordinate Two-Stream Approximation for Computation of Domain Averaged Solar Irradiance

    Science.gov (United States)

    Kato, S.; Smith, G. L.; Barker, H. W.

    2001-01-01

    An algorithm is developed for the gamma-weighted discrete ordinate two-stream approximation that computes profiles of domain-averaged shortwave irradiances for horizontally inhomogeneous cloudy atmospheres. The algorithm assumes that frequency distributions of cloud optical depth at unresolved scales can be represented by a gamma distribution though it neglects net horizontal transport of radiation. This algorithm is an alternative to the one used in earlier studies that adopted the adding method. At present, only overcast cloudy layers are permitted.

  13. Vibrational spectra and normal co-ordinate analysis of 2-aminopyridine and 2-amino picoline.

    Science.gov (United States)

    Jose, Sujin P; Mohan, S

    2006-05-01

    The Fourier transform infrared (FT-IR) and Raman (FT-R) spectra of 2-aminopyridine and 2-amino picoline were recorded and the observed frequencies were assigned to various modes of vibration in terms of fundamentals by assuming Cs point group symmetry. A normal co-ordinate analysis was also carried out for the proper assignment of the vibrational frequencies using simple valence force field. A complete vibrational analysis is presented here for the molecules and the results are briefly discussed.

  14. New developments in the discrete ordinate method for the resolution of the radiative transfer equation

    International Nuclear Information System (INIS)

    Ben Jaffel, L.; Vidal-Madjar, A.

    1989-01-01

    The discrete ordinate method for the resolution of the radiative transfer equation is developed. We show that the construction of a quasi-analytical solution to the corresponding matrix diagonalization problem reduces the time calculation and allows the use of more dense discrete frequency and angle grids. Comparison with previous work is made, showing that the present method reduces by more than a factor of ten the computational time, and is more appropriate in all cases

  15. A numerical method for multigroup slab-geometry discrete ordinates problems with no spatial truncation error

    International Nuclear Information System (INIS)

    Barros, R.C. de; Larsen, E.W.

    1991-01-01

    A generalization of the one-group Spectral Green's Function (SGF) method is developed for multigroup, slab-geometry discrete ordinates (S N ) problems. The multigroup SGF method is free from spatial truncation errors; it generated numerical values for the cell-edge and cell-average angular fluxes that agree with the analytic solution of the multigroup S N equations. Numerical results are given to illustrate the method's accuracy

  16. Discrete Ordinates Approximations to the First- and Second-Order Radiation Transport Equations

    CERN Document Server

    Fan, W C; Powell, J L

    2002-01-01

    The conventional discrete ordinates approximation to the Boltzmann transport equation can be described in a matrix form. Specifically, the within-group scattering integral can be represented by three components: a moment-to-discrete matrix, a scattering cross-section matrix and a discrete-to-moment matrix. Using and extending these entities, we derive and summarize the matrix representations of the second-order transport equations.

  17. Human responses to Florida red tides: policy awareness and adherence to local fertilizer ordinances.

    Science.gov (United States)

    Kirkpatrick, Barbara; Kohler, Kate; Byrne, Margaret; Fleming, Lora E; Scheller, Karen; Reich, Andrew; Hitchcock, Gary; Kirkpatrick, Gary; Ullmann, Steven; Hoagland, Porter

    2014-09-15

    To mitigate the damages of natural hazards, policy responses can be beneficial only if they are effective. Using a self-administered survey approach, this paper focuses on the adherence to local fertilizer ordinances (i.e., county or municipal rules regulating the application of fertilizer to private lawns or facilities such as golf courses) implemented in jurisdictions along the Southwest Florida coast in response to hazardous blooms of Florida red tides (Karenia brevis). These ordinances play a role in the context of evolving programs of water pollution control at federal, state, water basin, and local levels. With respect to policy effectiveness, while the strength of physical linkages is of critical importance, the extent to which humans affected are aware of and adhere to the relevant rules, is equally critical. We sought to understand the public's depth of understanding about the rationales for local fertilizer ordinances. Respondents in Sarasota, Florida, were asked about their fertilizer practices in an area that has experienced several major blooms of Florida red tides over the past two decades. A highly educated, older population of 305 residents and "snowbirds" reported relatively little knowledge about a local fertilizer ordinance, its purpose, or whether it would change the frequency, size, or duration of red tides. This finding held true even among subpopulations that were expected to have more interest in or to be more knowledgeable about harmful algal blooms. In the face of uncertain science and environmental outcomes, and with individual motivations at odds with evolving public policies, the effectiveness of local community efforts to decrease the impacts of red tides may be compromised. Targeted social-science research on human perceptions about the risks of Florida red tides and education about the rationales for potential policy responses are warranted. Copyright © 2014 Elsevier B.V. All rights reserved.

  18. Time Dependent Discrete Ordinates Neutron Transport Using Distribution Iteration in XYZ Geometry

    Science.gov (United States)

    2007-09-01

    of applications, one example being the determination of activation products in a fast-flux reactor . All current discrete ordi- nates implementations...ψj+1 that is accurate to (∆t′)2 term. Thus, this method will yield second-order local truncation error only with the extrap - olated fluxes and not...D. Computing Methods in Reactor Physics . Gordon and Breach, 1968. 9. Carlson B. G. and Lathrop K. D. The Method of Discrete Ordinates . Technical

  19. The three-dimensional, discrete ordinates neutral particle transport code TORT: An overview

    International Nuclear Information System (INIS)

    Azmy, Y.Y.

    1996-01-01

    The centerpiece of the Discrete Ordinates Oak Ridge System (DOORS), the three-dimensional neutral particle transport code TORT is reviewed. Its most prominent features pertaining to large applications, such as adjustable problem parameters, memory management, and coarse mesh methods, are described. Advanced, state-of-the-art capabilities including acceleration and multiprocessing are summarized here. Future enhancement of existing graphics and visualization tools is briefly presented

  20. Fermentation of pretreated corncob hemicellulose hydrolysate to ...

    African Journals Online (AJOL)

    To investigate the effect of unknown fermentation inhibitors in corncob hemicellulose acid hydrolysate processed by pretreatment and detoxification on fermentation, corncob hemicellulose acid hydrolysate and artificially prepared hydrolysate were fermented in parallel by Candida shehatae YHFK-2. The results show that ...

  1. Antibacterial effect of surface pretreatment techniques against ...

    African Journals Online (AJOL)

    (CFU/ml), respectively, among the groups evaluated (P < 0.05). Er:YAG laser irradiation and its combinations with other antibacterial surface pretreatment applications also inhibited the bacterial growth with, respectively, 1444, 406, and 294 CFU/ml bacterial recovery being more efficient than KTP laser irradiation and ozone ...

  2. Antibacterial Effect of Surface Pretreatment Techniques against ...

    African Journals Online (AJOL)

    2018-02-23

    Feb 23, 2018 ... of dentin chips were obtained from the cavity walls, and the number of bacteria recovered was counted. Kruskal–Wallis ... Keywords: Antibacterial effect, cavity surface pretreatment techniques, cavity preparation, dental, dental ... wavelengths for removing oral soft and dental hard tissues without pain relief, ...

  3. Bromine pretreated chitosan for adsorption of lead

    Indian Academy of Sciences (India)

    Pollution by heavy metals like lead (II) is responsible for health hazards and environmental degradation. Adsorption is a prevalent method applied for removal of heavy metal pollutants from water. This study explored adsorption performances of 30% bromine pretreated chitosan for lead (II) abatement from water. Bromine ...

  4. Life Cycle Assessment of pretreatment technologies for anaerobic digestion of source-separated organic household waste

    DEFF Research Database (Denmark)

    Naroznova, Irina; Møller, Jacob; Scheutz, Charlotte

    2013-01-01

    traditional pretreatment method using a screw press. The inventory of the technologies was constructed including the mass balance, amount of biogas produced, nutrient recovery rates, and produced biomass quality. The technologies were modelled in the LCA-model EASETECH and the potential environmental impacts...

  5. Tax revenue in Mississippi communities following implementation of smoke-free ordinances: an examination of tourism and economic development tax revenues.

    Science.gov (United States)

    McMillen, Robert; Shackelford, Signe

    2012-10-01

    There is no safe level of exposure to tobacco smoke. More than 60 Mississippi communities have passed smoke-free ordinances in the past six years. Opponents claim that these ordinances harm local businesses. Mississippi law allows municipalities to place a tourism and economic development (TED) tax on local restaurants and hotels/motels. The objective of this study is to examine the impact of these ordinances on TED tax revenues. This study applies a pre/post quasi-experimental design to compare TED tax revenue before and after implementing ordinances. Descriptive analyses indicated that inflation-adjusted tax revenues increased during the 12 months following implementation of smoke-free ordinances while there was no change in aggregated control communities. Multivariate fixed-effects analyses found no statistically significant effect of smoke-free ordinances on hospitality tax revenue. No evidence was found that smoke-free ordinances have an adverse effect on the local hospitality industry.

  6. Variable discrete ordinates method for radiation transfer in plane-parallel semi-transparent media with variable refractive index

    Science.gov (United States)

    Sarvari, S. M. Hosseini

    2017-09-01

    The traditional form of discrete ordinates method is applied to solve the radiative transfer equation in plane-parallel semi-transparent media with variable refractive index through using the variable discrete ordinate directions and the concept of refracted radiative intensity. The refractive index are taken as constant in each control volume, such that the direction cosines of radiative rays remain non-variant through each control volume, and then, the directions of discrete ordinates are changed locally by passing each control volume, according to the Snell's law of refraction. The results are compared by the previous studies in this field. Despite simplicity, the results show that the variable discrete ordinate method has a good accuracy in solving the radiative transfer equation in the semi-transparent media with arbitrary distribution of refractive index.

  7. Comparative techno-economic analysis of steam explosion, dilute sulfuric acid, ammonia fiber explosion and biological pretreatments of corn stover.

    Science.gov (United States)

    Baral, Nawa Raj; Shah, Ajay

    2017-05-01

    Pretreatment is required to destroy recalcitrant structure of lignocelluloses and then transform into fermentable sugars. This study assessed techno-economics of steam explosion, dilute sulfuric acid, ammonia fiber explosion and biological pretreatments, and identified bottlenecks and operational targets for process improvement. Techno-economic models of these pretreatment processes for a cellulosic biorefinery of 113.5 million liters butanol per year excluding fermentation and wastewater treatment sections were developed using a modelling software-SuperPro Designer. Experimental data of the selected pretreatment processes based on corn stover were gathered from recent publications, and used for this analysis. Estimated sugar production costs ($/kg) via steam explosion, dilute sulfuric acid, ammonia fiber explosion and biological methods were 0.43, 0.42, 0.65 and 1.41, respectively. The results suggest steam explosion and sulfuric acid pretreatment methods might be good alternatives at present state of technology and other pretreatment methods require research and development efforts to be competitive with these pretreatment methods. Copyright © 2017 Elsevier Ltd. All rights reserved.

  8. Effect of thermal pretreatment on equilibrium moisture content of lignocellulosic biomass.

    Science.gov (United States)

    Acharjee, Tapas C; Coronella, Charles J; Vasquez, Victor R

    2011-04-01

    The equilibrium moisture content (EMC) of raw lignocellulosic biomass, along with four samples subjected to thermal pretreatment, was measured at relative humidities ranging from 11% to 97% at a constant temperature of 30 °C. Three samples were prepared by treatment in hot compressed water by a process known as wet torrefaction, at temperatures of 200, 230, and 260 °C. An additional sample was prepared by dry torrefaction at 300 °C. Pretreated biomass shows EMC below that of raw biomass. This indicates that pretreated biomass, both dry and wet torrefied, is more hydrophobic than raw biomass. The EMC results were correlated with a recent model that takes into account additional non-adsorption interactions of water, such as mixing and swelling. The model offers physical insight into the water activity in lignocellulosic biomass. Copyright © 2011 Elsevier Ltd. All rights reserved.

  9. Rapid near infrared spectroscopy for prediction of enzymatic hydrolysis of corn bran after various pretreatments

    DEFF Research Database (Denmark)

    Baum, Andreas; Wittrup Agger, Jane; Meyer, Anne S.

    2012-01-01

    step is to increase the responsivity of the substrate to enzymatic attack and the type of pretreatment affects the enzymatic conversion efficiency. Destarched corn bran is a fibrous, heteroxylan-rich side-stream from the starch industry which may be used as a feedstock for bioethanol production...... or as a source of xylose for other purposes. In the present study we demonstrate the use of diffuse reflectance near infrared spectroscopy (NIR) as a rapid and non-destructive analytical tool for evaluation of pretreatment effects on destarched corn bran. NIR was used to achieve classification between 43...... differently pretreated corn bran samples using principal component analysis (PCA) and hierarchal clustering algorithms. Quantification of the enzymatically released monosaccharides by HPLC was used to design multivariate calibration models (biPLS) on the NIR spectra. The models could predict the enzymatic...

  10. Guidelines for the implementation of the X-ray Ordinance (RoeV). Vol. 2. Recommendations concerning data acquisition and archivation pursuant to paragraph 28 of the X-ray Ordinance passed by the Laender Committee for the X-ray Ordinance, 26/27 January 1989

    International Nuclear Information System (INIS)

    1990-01-01

    The recommendations apply to biomedical radiography and X-ray therapy. They refer to: 1) Patients' personal data as required according to Paragraph 28, sub-sec. 1, X-ray Ordinance. 2) Scope of data to be recorded acc. to Paragraph 28, sub-sec. 2, X-ray Ordinance. 3) Archivation of data acc. to Paragraph 28, sub-sec., 4 + 5, X-ray Ordinance. 4) Passing on of data acc. to Paragraph 28, sub-sec. 6, X-ray Ordinance. 5) Archivation of technical standard data (X-ray equipment specification records). The recommendations' main aim is to provide for radiological protection of the patient and for data showing the radiation doses received by patients. (HP) [de

  11. Ethanol production from cotton gin trash using optimised dilute acid pretreatment and whole slurry fermentation processes.

    Science.gov (United States)

    McIntosh, S; Vancov, T; Palmer, J; Morris, S

    2014-12-01

    Cotton ginning trash (CGT) collected from Australian cotton gins was evaluated for bioethanol production. CGT composition varied between ginning operations and contained high levels of extractives (26-28%), acid-insoluble material (17-22%) and holocellulose (42-50%). Pretreatment conditions of time (4-20 min), temperature (160-220 °C) and sulfuric acid concentration (0-2%) were optimised using a central composite design. Response surface modelling revealed that CGT fibre pretreated at 180 °C in 0.8% H2SO4 for 12 min was optimal for maximising enzymatic glucose recoveries and achieved yields of 89% theoretical, whilst the total accumulated levels of furans and acetic acid remained relatively low at <1 and 2 g/L respectively. Response surface modelling also estimated maximum xylose recovery in pretreated liquors (87% theoretical) under the set conditions of 150 °C in 1.9% H2SO4 for 23.8 min. Yeast fermentations yielded high ethanol titres of 85%, 88% and 70% theoretical from glucose generated from: (a) enzymatic hydrolysis of washed pretreated fibres, (b) enzymatic hydrolysis of whole pretreated slurries and (c) simultaneous saccharification fermentations, respectively. Crown Copyright © 2014. Published by Elsevier Ltd. All rights reserved.

  12. Detection of Soil Nitrogen Using Near Infrared Sensors Based on Soil Pretreatment and Algorithms.

    Science.gov (United States)

    Nie, Pengcheng; Dong, Tao; He, Yong; Qu, Fangfang

    2017-05-11

    Soil nitrogen content is one of the important growth nutrient parameters of crops. It is a prerequisite for scientific fertilization to accurately grasp soil nutrient information in precision agriculture. The information about nutrients such as nitrogen in the soil can be obtained quickly by using a near-infrared sensor. The data can be analyzed in the detection process, which is nondestructive and non-polluting. In order to investigate the effect of soil pretreatment on nitrogen content by near infrared sensor, 16 nitrogen concentrations were mixed with soil and the soil samples were divided into three groups with different pretreatment. The first group of soil samples with strict pretreatment were dried, ground, sieved and pressed. The second group of soil samples were dried and ground. The third group of soil samples were simply dried. Three linear different modeling methods are used to analyze the spectrum, including partial least squares (PLS), uninformative variable elimination (UVE), competitive adaptive reweighted algorithm (CARS). The model of nonlinear partial least squares which supports vector machine (LS-SVM) is also used to analyze the soil reflectance spectrum. The results show that the soil samples with strict pretreatment have the best accuracy in predicting nitrogen content by near-infrared sensor, and the pretreatment method is suitable for practical application.

  13. Evaluating the impact of ammonia fiber expansion (AFEX) pretreatment conditions on the cost of ethanol production.

    Science.gov (United States)

    Bals, Bryan; Wedding, Chris; Balan, Venkatesh; Sendich, Elizabeth; Dale, Bruce

    2011-01-01

    Ammonia fiber expansion (AFEX) pretreatment is an ammonia-based process for improving the susceptibility of lignocellulosic biomass to enzymatic attack. Four parameters--ammonia loading, water loading, reaction temperature, and residence time--can be varied in order to optimize AFEX pretreatment. The effect of these parameters on process economics of ethanol production was studied using a leading biorefinery model. Ammonia loading and residence time had the greatest impact on the economics of ethanol production, primarily due to processing costs for the chilled water condenser and the capital cost of the AFEX reactor. Water loading and reaction temperature had only modest impact on process economics. In addition, the impact of pretreatment conditions on makeup ammonia requirements was explored experimentally, which ranged from 15 to 25 g ammonia/kg biomass. Overall, pretreatment conditions can change the costs of ethanol production by up to 35 cents per gallon ethanol in an 850 ton/day refinery. By linking the results obtained from this Aspen model to experimental results for ethanol production and makeup ammonia recovery, this study can be used to create an economic optimum for AFEX pretreatment in contrast with simply maximizing fermentable sugar production. Copyright © 2010 Elsevier Ltd. All rights reserved.

  14. First research co-ordination meeting of the co-ordinated research programme on development of kits for radioimmunometric assays for tumour markers. Summary report

    International Nuclear Information System (INIS)

    1997-01-01

    Cancer is one of the major reasons for mortality and a great deal of research goes on in many areas related to cancer all through the world. The concept of 'tumor markers' has greatly aided the management of cancer, especially for follow up of the treated patients. Immunoassays that are used for measurement of sub-picomolar quantities of biomolecules such as hormones have been developed for the measurement of tumor markers too and these are widely used for monitoring the patients. The current co-ordinated research program on 'Development of Immunometric Assays for the Tumor Makers: PSA, free PSA and TPS' was born out of the advise from a group of specialists from the field oncology and nuclear medicine who met to discuss initially (Advisory Group Meeting, Colombo, August 1996) to identify the most appropriate markers and later (Consultants' Meeting, Glasgow, 21-25 April 1997) to identify the details of the procedure to follow. The first Research Co-ordination Meeting of this group was held in Vienna from 9-12 December 1997 to review the plans of each participant and the steps to be taken to realize the goal of this CRP. The meeting was attended by participants from the ten laboratories. The meeting discussed all salient aspects of the IRMA development for PSA and TPS. The modalities of working out the plans were thoroughly considered and the key inputs for the program to take off were identified. In conclusion, all the nine contract holding participants would develop the IRMAs for PSA (free and total) and TPS (Uruguay)

  15. Microscale modelling of ambient air concentrations resulting from the increased combustion of biomass firing systems within the 1{sup st} Ordinance for the Implementation of the Federal Immission Control Act (1. BImSchV); Modellrechnungen zu den Immissionsbelastungen bei einer verstaerkten Verfeuerung von Biomasse in Feuerungsanlagen der 1. BImSchV

    Energy Technology Data Exchange (ETDEWEB)

    Baumbach, Guenter; Struschka, Michael; Juschka, Winfried; Carrasco, Maria; Ang, Keng Been; Hu, Lupin [Stuttgart Univ. (DE). Inst. fuer Verfahrenstechnik und Dampfkesselwesen (IVD); Baechlin, Wolfgang; Soergel, Christine [Ingenieurbuero Lohmeyer GmbH und Co. KG, Karlsruhe (Germany)

    2010-06-15

    By means of a detailed emissions modelling with subsequent highly resolved ambient air pollutant dispersion modelling an assessment method has been developed. This method is a tool for city planners to assess the effects of an increased usage of biomass in heating firings on the air quality situation in different residential areas. Emission simulations have been carried out for the combustion of wood pellets, log wood, wood chips and grain residues as well as for natural gas and heating oil. The emissions depend on the ambient temperature, the building and user specific heat demand and on the operation conditions of the firing. For the operation conditions different emission factors have been set for nominal and partial load as well as for unsteady conditions like boiler start or for shutdown of the firing. The following firings have been considered for burning the above mentioned fuels: Central heating boilers, decentralised heating networks with pellet and wood chip boilers, single stoves for additional heating and grain residue furnaces. Dependent on the ambient temperature for different regions of Germany and for a reference year of the Deutsche Wetterdienst annual emission time series with 1h resolution have been calculated for the different firing fuel combinations. Using these modelled emission data dispersion modelling was carried out for different meteorological and building specific frame conditions. A rural and an urban model area have been investigated. The emissions time series which were calculated for the individual buildings with 1h time resolution were spatially allocated and each single chimney was simulated as point source. For modelling the flow field coined by the building structure the flow model MISKAM has been applied. For dispersion simulation the model AUSTAL2000 has been used. Simulations have been carried out with three different wind and dispersion class distributions typical for many regions of Germany. A further parameter variation

  16. A novel free ammonia based pretreatment technology to enhance anaerobic methane production from primary sludge.

    Science.gov (United States)

    Wei, Wei; Zhou, Xu; Xie, Guo-Jun; Duan, Haoran; Wang, Qilin

    2017-10-01

    This study proposed a novel free ammonia (FA, i.e., NH 3 ) pretreatment technology to enhance anaerobic methane production from primary sludge for the first time. The solubilization of primary sludge was substantially enhanced following 24 h FA pretreatment (250-680 mg NH 3 -N/L), by which the release of soluble chemical oxygen demand (SCOD) (i.e., 0.4 mg SCOD/mg VS added; VS: volatile solids) was approximately 10 times as much as that without pretreatment (i.e., 0.03 mg SCOD/mg VS added). Then, biochemical methane potential (BMP) tests demonstrated that FA pretreatment of 250-680 mg NH 3 -N/L was capable of enhancing anaerobic methane production while the digestion time was more than 7 days. Model based analysis indicated that the improved anaerobic methane production was due to an increased biochemical methane potential (B 0 ) of 8-17% (i.e., from 331 to 357-387 L CH 4 /kg VS added), with the highest B 0 achieved at 420 mg NH 3 -N/L pretreatment. However, FA pretreatment of 250-680 mg NH 3 -N/L decreased hydrolysis rate (k) by 24-38% compared with control (i.e., from 0.29 d -1 to 0.18-0.22 d -1 ), which explained the lower methane production over the first 7 days' digestion period. Economic analysis and environmental evaluation demonstrated that FA pretreatment technology was environmentally friendly and economically favorable. Biotechnol. Bioeng. 2017;114: 2245-2252. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

  17. Pretreatment of Latent Prints for Laser Development.

    Science.gov (United States)

    Menzel, E R

    1989-06-01

    The pretreatment procedures for laser detection of latent fingerprints is reviewed. The general features of laser detection and the operational aspects of the examination of physical evidence for laser fingerprint detection are enumerated in the initial sections. The literature review is divided into various pretreatment approaches. Cited studies prior to 1981 are primarily concerned with the demonstration of the viability of laser fingerprint detection, whereas work post-1981 addresses issues of compatibility with the traditional methods of fingerprint development, examination of difficult surfaces, and the routine implementation of laser detection by law enforcement agencies. Related topics of research, review articles, conference reports, case examinations, the research support climate, and future trends are also briefly addressed. Copyright © 1989 Central Police University.

  18. Pretreatment of Dioscorea zingiberensis for Microbial Transformation

    Directory of Open Access Journals (Sweden)

    Tianxiang Zheng

    2014-09-01

    Full Text Available The influences of five pretreatments on fungal growth and enzyme production during microbial transformation of Dioscorea zingiberensis (DZW were studied. The biomass, α-rhamnase and β-glucosidase activities in the fermentation system were employed in the study to determine how each method affected the efficiency of microbial transformation. The fungal strain grew better on the substrate which contained easily utilized carbon source. While lack of carbon source induced the strain produce more glucosidase. Among five pretreatment methods, complex enzymatic hydrolyzation can remove 84.3% starch and 76.5% fibre from DZW in form of sugar, which resulted in high α-rhamnase activity of 2.89 IU/mL and β-glucosidase activity of 8.17 IU/mL in fermentation broth.

  19. Pretreatment Capabilities and Benefits of Electrocoagulation

    Science.gov (United States)

    2004-12-01

    4.1.1.2 Oil-Water Emulsions – Mock Solutions ………………… 20 4.1.1.3 Tannin and Humic Acid Mixture – Mock Solutions …….. 35 4.1.1.4 Silt – Mock...water Influent/ effluent water control Industrial wastewater Pre-treatment for drinking water Oil emulsion breaking Medical waste

  20. Hydrothermal pretreatments of macroalgal biomass for biorefineries

    DEFF Research Database (Denmark)

    Ruiz, Héctor A.; Rodríguez-Jasso, Rosa M.; Aguedo, Mario

    2015-01-01

    ecently, macroalgal biomass is gaining wide attention as an alternative in the production of biofuels (as bioetanol and biogas) and compounds with high added value with specific properties (antioxidants, anticoagulants, anti–inflammatories) for applications in food, medical and energy industries...... in accordance with the integrated biorefineries. Furthermore, biorefinery concept requires processes that allow efficient utilization of all components of the biomass. The pretreatment step in a biorefinery is often based on hydrothermal principles of high temperatures in aqueous solution. Therefore...

  1. Waste Separations and Pretreatment Workshop report

    International Nuclear Information System (INIS)

    Cruse, J.M.; Harrington, R.A.; Quadrel, M.J.

    1994-01-01

    This document provides the minutes from the Waste Separations and Pretreatment Workshop sponsored by the Underground Storage Tank-Integrated Demonstration in Salt Lake City, Utah, February 3--5, 1993. The Efficient Separations and Processing-Integrated Program and the Hanford Site Tank Waste Remediation System were joint participants. This document provides the detailed minutes, including responses to questions asked, an attendance list, reproductions of the workshop presentations, and a revised chart showing technology development activities

  2. Cost comparison for REDC pretreatment project

    International Nuclear Information System (INIS)

    Robinson, S.M.; Homan, F.J.

    1997-06-01

    This analysis has been prepared to support the planned expenditure to provide the Radiochemical Engineering Development Center (REDC) with the capability to pretreat their liquid low-level waste (LLLW) before discharging it to the Oak Ridge National Laboratory (ORNL) LLLW system. Pretreatment will remove most of the radioactivity, particularly the transuranic isotopes and Cs-137 from the waste to be discharged. This will render the supernates that accumulate in the storage tanks low-activity Class B low-level wastes rather than high-activity Class B or Class C wastes. The sludges will be Class C rather than remote-handled transuranic (RH-TRU) wastes. When REDC wastes are commingled with other ORNL LLLW, the present-worth treatment and transport costs are higher by a factor of 1.3 for the no-pretreatment cases. This result is consistent with data from similar studies conducted at other sites. Based on the information presented in this analysis, the recommendation is to proceed with REDC treatment projects

  3. Pretreatment of Agave americana stalk for enzymatic saccharification.

    Science.gov (United States)

    Yang, Qiang; Pan, Xuejun

    2012-12-01

    Agave americana is one of commonly grown agave species but currently less valuable because its large flower stalk cannot be used for producing alcoholic beverage. In the present study, the stalk was pretreated with dilute acid (DA), sulfite (SPORL), and sodium hydroxide (NaOH) to preliminarily assess its potential as feedstock for bioethanol production. The changes of cell wall components during the pretreatments, enzymatic digestibility of the pretreated stalks, and the adsorption of cellulases on the substrates were investigated. Results indicated that the pretreatments significantly improved the enzymatic digestibility of the agave stalk. SPORL pretreatment gave higher substrate and sugar yields, while NaOH pretreated stalk had better digestibility under the investigated conditions. The better hydrolysability of NaOH-pretreated stalk was attributed to low lignin and hemicellulose content and high affinity to cellulases. Copyright © 2012 Elsevier Ltd. All rights reserved.

  4. Co-ordinated research activities: Annual report and statistics for 2003

    International Nuclear Information System (INIS)

    2004-07-01

    Article III of the IAEA Statute authorises the Agency to encourage and assist research on, and development and practical application of, atomic energy for peaceful purposes throughout the world and to foster the exchange of scientific and technical information, as well as the exchange of scientists in the field of peaceful uses of atomic energy. The research supported by the Agency is within the framework of the Agency's programmes, sub-programmes and projects that are listed in the approved Programme and Budget of the Agency. These co-ordinated research activities are normally implemented through Co-ordinated Research Projects (CRPs) that bring together research institutes in both developing and developed Member States to collaborate on the research topic of interest. The Agency may also respond to proposals from institutes for participation in the research activities by awarding individual contracts not related to a CRP. A small portion of available funds is used to finance individual projects, which deal with topics covered by the Agency's scientific programme. The Agency also supports several Doctoral CRPs. This new, optional type of CRP has been designed to strengthen promotion of research on nuclear technologies in developing Member States through pair building between agreement holders and contract holders. These CRPs include a PhD training programme at the contract holders' institutions. Three doctoral CRPs are currently being carried out by the Human Health programme. Further information on the Agency's co-ordinated research activities, including current information on CRPs and programme areas supported, information on policies and procedures and the administration of the activities is contained in the Agency's website at http://www-crp.iaea.org. The co-ordinated research activities reported in this document are conducted in support of the following Agency programmes: Nuclear Power; Nuclear Fuel Cycle and Material Technologies; Analysis for Sustainable

  5. Free nitrous acid (FNA)-based pretreatment enhances methane production from waste activated sludge.

    Science.gov (United States)

    Wang, Qilin; Ye, Liu; Jiang, Guangming; Jensen, Paul D; Batstone, Damien J; Yuan, Zhiguo

    2013-10-15

    Anaerobic digestion of waste activated sludge (WAS) is currently enjoying renewed interest due to the potential for methane production. However, methane production is often limited by the slow hydrolysis rate and/or poor methane potential of WAS. This study presents a novel pretreatment strategy based on free nitrous acid (FNA or HNO2) to enhance methane production from WAS. Pretreatment of WAS for 24 h at FNA concentrations up to 2.13 mg N/L substantially enhanced WAS solubilization, with the highest solubilization (0.16 mg chemical oxygen demand (COD)/mg volatile solids (VS), at 2.13 mg HNO2-N/L) being six times that without FNA pretreatment (0.025 mg COD/mg VS, at 0 mg HNO2-N/L). Biochemical methane potential tests demonstrated methane production increased with increased FNA concentration used in the pretreatment step. Model-based analysis indicated FNA pretreatment improved both hydrolysis rate and methane potential, with the highest improvement being approximately 50% (from 0.16 to 0.25 d(-1)) and 27% (from 201 to 255 L CH4/kg VS added), respectively, achieved at 1.78-2.13 mg HNO2-N/L. Further analysis indicated that increased hydrolysis rate and methane potential were related to an increase in rapidly biodegradable substrates, which increased with increased FNA dose, while the slowly biodegradable substrates remained relatively static.

  6. Comprehensive review and compilation of pretreatments for mesophilic and thermophilic anaerobic digestion.

    Science.gov (United States)

    Bordeleau, É L; Droste, R L

    2011-01-01

    Organic matter hydrolysis prior to anaerobic digestion has been shown to improve biogas production (30-50%) and reduce solids (20-60%) by ultrasound, chemical, conventional heating, and microwave pretreatments. Numerous studies have been performed to determine the extent of digestion improvement but few focus on financial feasibility of these processes. A comprehensive model was created using Microsoft Excel and its Visual Basic Assistant to evaluate pretreatment permutations for conventional wastewater treatment plants. The four above-mentioned processes were evaluated for energetic and financial demands. Well-established energy equations and wastewater characteristics, both average and high, were used. Average and high flows were 460 and 750×10(3) m3/d, respectively. Net costs per influent flow for ultrasound, chemical, conventional heating, and microwave were 0.0166, 0.0217, 0.0124, 0.0119 $/m3 and 0.0264, 0.0357, 0.0187, and 0.0162 $/m3 for average and high conditions, respectively. The average cost increase from results excluding pretreatment use for all processes was 0.003 and 0.0055 $/m3 for average and high conditions, respectively. No matter the permutation, pretreatments requiring more energy to achieve required hydrolysis levels were costlier. If energetic recoveries are substantial, dewaterability is positively affected, and solids meet environmental constraints to be handled and disposed at lower costs, pretreatments can be viable.

  7. Dry ice blasting as a substitution for the conventional electroplating pre-treatments

    Directory of Open Access Journals (Sweden)

    Uhlmann Eckart

    2016-01-01

    Full Text Available For high quality electroplated products, surfaces must be thoroughly pre-treated. For this purpose electroplating currently needs a variety of chemical baths. The used chemicals are injurious to health and harmful to the environment. In addition, the conventional pre-treatment has a long process time which results in high costs. Dry ice blasting alone or in combination with other processes has the potential to completely substitute these conventional pre-treatment processes. Three process sequences as pre-treatment methods prior to electroplating were investigated on the aluminium alloys AlSi12 and AlMg3. The used processes are dry ice blasting, tempering during dry ice blasting and glass bead blasting followed by dry ice blasting. The influence of the parameters on the surface roughness, surface topography and surface tension of the workpieces was examined. A model to describe the correlation between the dry ice blasting parameters and surface parameters was developed. Finally, an adhesion test of electroplated specimen was conducted in order to determine the suitability of these alternative pre-treatment processes.

  8. Discrete-ordinates quadrature sets based on linear discontinuous finite elements

    International Nuclear Information System (INIS)

    Jarrell, Joshua J.; Adams, Marvin L.

    2011-01-01

    We describe new quadrature sets based on linear discontinuous nite element (LDFE) basis functions de ned on the unit sphere. We describe the construction of these sets, demonstrate the accuracy with which they integrate polynomials in the direction cosines, and demonstrate their performance on a set of test problems. We develop the new quadrature sets by dividing the faces of a regular octahedron into equilateral triangles and projecting these onto 'spherical triangles' on the surface of the unit sphere. We choose four quadrature points per triangle and de ne LDFE interpolating basis functions in the direction cosines. A quadrature point's weight is the integral of its basis function over its triangle. Variations in the locations of the four points produce variations in the quadrature sets. The equilateral triangles can be subdivided recursively to create ner quadrature sets, including locally re ned sets that are suitable for use in adaptive algorithms. We analyze a simple one-cell problem and a more complex skewed-duct problem and compare our LDFE quadrature sets to those normally used in the neutral particle discrete-ordinate eld such as level symmetric, Gauss- Chebyshev, and Quadruple Range (QR) sets. The LDFE and QR sets show fourth-order convergence in the simple problem, while the other sets exhibit second or lower order. The LDFE sets exhibit more accurate solutions for the scalar flux in both problems and are not limited by mathematical complexity or by negativity of the discrete-ordinate weights. The same is true for results from other test problems that are not shown here. We conclude that the new LDFE quadrature sets are a promising option for discrete-ordinates transport calculations. However, we note that further studies are needed, especially in problems with highly anisotropic scattering, before the utility of these sets is fully determined. (author)

  9. Case management for high-intensity service users: towards a relational approach to care co-ordination.

    Science.gov (United States)

    McEvoy, Phil; Escott, Diane; Bee, Penny

    2011-01-01

    This study is based on a formative evaluation of a case management service for high-intensity service users in Northern England. The evaluation had three main purposes: (i) to assess the quality of the organisational infrastructure; (ii) to obtain a better understanding of the key influences that played a role in shaping the development of the service; and (iii) to identify potential changes in practice that may help to improve the quality of service provision. The evaluation was informed by Gittell's relational co-ordination theory, which focuses upon cross-boundary working practices that facilitate task integration. The Assessment of Chronic Illness Care Survey was used to assess the organisational infrastructure and qualitative interviews with front line staff were conducted to explore the key influences that shaped the development of the service. A high level of strategic commitment and political support for integrated working was identified. However, the quality of care co-ordination was variable. The most prominent operational factor that appeared to influence the scope and quality of care co-ordination was the pattern of interaction between the case managers and their co-workers. The co-ordination of patient care was much more effective in integrated co-ordination networks. Key features included clearly defined, task focussed, relational workspaces with interactive forums where case managers could engage with co-workers in discussions about the management of interdependent care activities. In dispersed co-ordination networks with fewer relational workspaces, the case managers struggled to work as effectively. The evaluation concluded that the creation of flexible and efficient task focused relational workspaces that are systemically managed and adequately resourced could help to improve the quality of care co-ordination, particularly in dispersed networks. © 2010 Blackwell Publishing Ltd.

  10. New methods and techniques for decontamination in maintenance or decommissioning operations. Results of a co-ordinated research programme 1994-1998

    International Nuclear Information System (INIS)

    1998-06-01

    Decontamination of nuclear facilities is a subject of increasing importance as the nuclear community considers the issues related to the decommissioning of surplus or obsolete facilities and making modifications to operational facilities, or conducts the necessary inspections and maintenance to permit continued efficient and safe operation of existing facilities. Previous co-ordinated research programmes (CRP) conducted respectively from 1984 to 1987, and from 1989 to 1993, highlighted the role of decontamination within the overall domain of decommissioning. Having recognized technological progress in decontamination and the large potential for optimization, the CRP on New Methods and Techniques for Optimization of Decontamination for Maintenance or Decommissioning was launched and conducted by the IAEA from 1994 to 1998. Concluding reports that summarized the work undertaken under the aegis of the CRP were presented at the third and final Research Co-ordination Meeting (RCM) held in Mol, Belgium, 12-16 January 1998 and are collected in this Technical Document. Operating experience in real-scale applications, lessons learned, key results in laboratory scale or pilot scale research, and validation of mathematical models, are among the most significant achievements of the CRP and have been highlighted

  11. Co-ordinate decrease in the expression of the mitochondrial genome and nuclear genes for mitochondrial proteins in the lactation-induced mitochondrial hypotrophy of rat brown fat.

    Science.gov (United States)

    Martin, I; Giralt, M; Viñas, O; Iglesias, R; Mampel, T; Villarroya, F

    1995-01-01

    The relative abundance of the mitochondrial-encoded mRNAs for cytochrome c oxidase subunit II and NADH dehydrogenase subunit I was lower in brown adipose tissue (BAT) from lactating rats than in virgin controls. This decrease was in parallel with a significant decrease in mitochondrial 16 S rRNA levels and in the relative content of mitochondrial DNA in the tissue. BAT from lactating rats showed lowered mRNA expression of the nuclear-encoded genes for the mitochondrial uncoupling protein, subunit IV of cytochrome c oxidase and the adenine nucleotide translocase isoforms ANT1 and ANT2, whereas mRNA levels for the ATP synthase beta-subunit were unchanged. However, the relative content of this last protein was lower in BAT mitochondria from lactating rats than in virgin controls. It is concluded that lactation-induced mitochondrial hypotrophy in BAT is associated with a co-ordinate decrease in the expression of the mitochondrial genome and nuclear genes for mitochondrial proteins. This decrease is caused by regulatory events acting at different levels, including pre- and post-transcriptional regulation. BAT appears to be a useful model with which to investigate the molecular mechanisms involved in the co-ordination of the expression of the mitochondrial and nuclear genomes during mitochondrial biogenesis. Images Figure 1 Figure 2 PMID:8948428

  12. Changes in the oligomerization potential of the division inhibitor UgtP co-ordinate Bacillus subtilis cell size with nutrient availability.

    Science.gov (United States)

    Chien, An-Chun; Zareh, Shannon Kian Gharabiklou; Wang, Yan Mei; Levin, Petra Anne

    2012-11-01

    How cells co-ordinate size with growth and development is a major, unresolved question in cell biology. In previous work we identified the glucosyltransferase UgtP as a division inhibitor responsible for increasing the size of Bacillus subtilis cells under nutrient-rich conditions. In nutrient-rich medium, UgtP is distributed more or less uniformly throughout the cytoplasm and concentrated at the cell poles and/or the cytokinetic ring. Under these conditions, UgtP interacts directly with FtsZ to inhibit division and increase cell size. Conversely, under nutrient-poor conditions, UgtP is sequestered away from FtsZ in punctate foci, and division proceeds unimpeded resulting in a reduction in average cell size. Here we report that nutrient-dependent changes in UgtP's oligomerization potential serve as a molecular rheostat to precisely co-ordinate B. subtilis cell size with nutrient availability. Our data indicate UgtP interacts with itself and the essential cell division protein FtsZ in a high-affinity manner influenced in part by UDP glucose, an intracellular proxy for nutrient availability. These findings support a model in which UDP-glc-dependent changes in UgtP's oligomerization potential shift the equilibrium between UgtP•UgtP and UgtP•FtsZ, fine-tuning the amount of FtsZ available for assembly into the cytokinetic ring and with it cell size. © 2012 Blackwell Publishing Ltd.

  13. Generalized perturbation theory using two-dimensional, discrete ordinates transport theory

    International Nuclear Information System (INIS)

    Childs, R.L.

    1979-01-01

    Perturbation theory for changes in linear and bilinear functionals of the forward and adjoint fluxes in a critical reactor has been implemented using two-dimensional discrete ordinates transport theory. The computer program DOT IV was modified to calculate the generalized functions Λ and Λ*. Demonstration calculations were performed for changes in a reaction-rate ratio and a reactivity worth caused by system perturbations. The perturbation theory predictions agreed with direct calculations to within about 2%. A method has been developed for calculating higher lambda eigenvalues and eigenfunctions using techniques similar to those developed for generalized functions. Demonstration calculations have been performed to obtain these eigenfunctions

  14. Evaluation of Boulder, CO, SmartRegs Ordinance and Better Buildings Program

    Energy Technology Data Exchange (ETDEWEB)

    Arena, L.; Vijayakumar, G.

    2012-04-01

    Under the SmartRegs ordinance in the city of Boulder, Colorado, all rental properties in the city must achieve an energy efficiency level comparable to a HERS Index of approximately 120 points or lower by the year 2019. The City of Boulder received a $12 million grant from the DOE's Better Buildings initiative to create and incentivize their EnergySmart Program. In this report, the Consortium for Advanced Residential Buildings (CARB) describes its work with the program, including energy audits of rental properties, developing training programs for insulators and inspectors, and conducting interviews with property owners.

  15. Evaluation of Boulder, CO,SmartRegs Ordinance and Better Buildings Program

    Energy Technology Data Exchange (ETDEWEB)

    Arena, L. [Consortium for Advanced Residential Buildings (CARB), Norwalk, CT (United States); Vijayakumar, G. [Consortium for Advanced Residential Buildings (CARB), Norwalk, CT (United States)

    2012-04-01

    Under the SmartRegs ordinance in the city of Boulder, Colorado, all rental properties in the city must achieve an energy efficiency level comparable to a HERS Index of approximately 120 points or lower by the year 2019. The City of Boulder received a $12 million grant from the DOE’s Better Buildings initiative to create and incentivize their EnergySmart Program. In this report, the Consortium for Advanced Residential Buildings (CARB) describes its work with the program, including energy audits of rental properties, developing training programs for insulators and inspectors, and conducting interviews with property owners.

  16. 1984 Ordinance on definitions and licences in the atomic energy field. Amendment of 2 March 1987

    International Nuclear Information System (INIS)

    1987-01-01

    Following the partial revision of the Federal Act of 23rd December 1959 on atomic energy concerning import and export of nuclear items and technology the Ordinance of 18th January 1984 on definitions and licensing in the atomic energy field was also amended. The mandatory licensing system now covers the export of technologies (unpublished technical data concerning installations for the enrichment and reprocessing of nuclear fuels as well as for heavy water production). This amendment became effective on 1st April 1987. (NEA) [fr

  17. Nuclear techniques in the coal industry. Proceedings of a final research co-ordination meeting

    International Nuclear Information System (INIS)

    1995-11-01

    With the aim of promoting advanced research and facilitating a more extensive application of nuclear techniques for environmental protection in the exploration and exploitation of coal, the IAEA established the present co-ordinated research programme (CRP) in 1989. This report includes an assessment of the current status and trends in nuclear techniques in the coal industry and the results obtained by the participants at the CRP. Proceedings of the final CRP on ''Nuclear Techniques in Exploration and Exploitation of Coal: On-line and Bulk Analysis and Evaluation of Potential Environmental Pollutants in Coal and Coke'', was held in Krakow, Poland, from 9 to 12 May 1994. Refs, figs, tabs

  18. Ministry of ordinance determining the technical standard concerning atomic energy facilities for power generation

    International Nuclear Information System (INIS)

    1985-01-01

    The ministerial ordinance provides for the technical standards for the power generation of nuclear facilities; i.e., electric power facilities generating electricity with nuclear energy for motive power, according to the Electricity Enterprises Act. The contents are as follows: protection against fires, aseismatic design, radiation protective barriers, structural protection for sitings, reactor installation, safety measures, materials and structures, safety valves, pressure resistance tests, reactor core, radiation shields, reactor cooling, emergency core cooling system, facility equipment, alarm system, reactor control system, reactor control room, fuel storage facility, fuel handling facility, ventilation equipment, radioactive contamination prevention, radioactive waste management facility, reactor containment facility, and so on. (Kubozono, M.)

  19. Analysis of Indonesia Confucians Understanding Towards Religious Doctrines and Ordinances in Confucianism

    Directory of Open Access Journals (Sweden)

    Sugiato Lim

    2013-10-01

    Full Text Available To a great extent, daily life of Indonesia Chinese community is filled with religious overtones. This paper basically analyzes the understanding of Indonesia Confucians towards their religion. The first part of this paper will be discussing about the general definition of religion and its religious elements. The second part will analyze the understanding of Indonesia Confucians towards their religious doctrines and ordinances respectively. In conclusion, overview regarding Indonesia Confucians and a special historical background of Indonesia Confucianism, which consists of its formation and development as a legal religion in line with Indonesia national conditions, social conditions and characteristic, will be presented.   

  20. Insulation co-ordination in high-voltage electric power systems

    CERN Document Server

    Diesendorf, W

    2015-01-01

    Insulation Co-ordination in High-Voltage Electric Power Systems deals with the methods of insulation needed in different circumstances. The book covers topics such as overvoltages and lightning surges; disruptive discharge and withstand voltages; self-restoring and non-self-restoring insulation; lightning overvoltages on transmission lines; and the attenuation and distortion of lightning surges. Also covered in the book are topics such as the switching surge designs of transmission lines, as well as the insulation coordination of high-voltage stations. The text is recommended for electrical en