WorldWideScience

Sample records for model phys rev

  1. Comments on Phys. Rev. D89 (2014) 097101 "Reevaluation of the parton distribution of strange quarks in the nucleon"

    CERN Document Server

    Stolarski, M

    2014-01-01

    The HERMES collaboration in Phys. Rev. D89 (2014) 097101 extracted information about the strange quark density in the nucleon. One of the main results is an observation that the shape of the extracted density is very different from the shapes of the strange quark density from global QCD fits and also from that of the light antiquarks. In this paper systematic studies on the HERMES published multiplicity of pion and kaon data are presented. It is shown that the conclusions concerning the strange quark distribution in the nucleon reached in Phys. Rev. D89 (2014) 097101 are at the moment premature.

  2. Reply Comments on Phys. Rev. D89, 097101 (2014) "Reevaluation of the parton distribution of strange quarks in the nucleon"

    CERN Document Server

    Aschenauer, E C; Joosten, S; Rith, K; Schnell, G; Van Hulse, C

    2015-01-01

    In the "Comments on Phys. Rev. D89, 097101 (2014)", the Author presents a number of studies to conjecture that the analysis by the HERMES Collaboration presented in Phys. Rev. D89, 097101 (2014) likely suffers from effects that invalidate the leading-order analysis used in that publication. In our opinion, the Author has drawn erroneous conclusions. We present below a discussion of his arguments and the results from a repetition of that analysis using a range of parton distribution sets. The spread in those results precludes credible conclusions and demonstrates the sensitivity of the analysis to poorly known input data (unfavored FFs, strange-quark distributions, and mixed singlet and nonsinglet quantities).

  3. Comment on "Total Negative Refraction in Real Crystals for Ballistic Electrons and Light" (Phys. Rev. Lett. 91, 157404 (2003))

    OpenAIRE

    Yau, H. -F.; Liu, J.-P.; Ke, B; Kuo, C. -H.; Ye, Z.

    2003-01-01

    Recently, Zhang et al. (Phys. Rev. Lett. 91, 157404 (2003)) have demonstrated that an amphoteric refraction, i. e. both positive and negative refraction, may prevail at the interface of two uniaxial anisotropic crystals when their optical axes are in different directions. The authors subsequently made a correspondence between such a refraction with the negative refraction expected for Left Handed Materials (LHMs). Here we comment that the amphoteric refraction can be observed even with one un...

  4. Comment on “Diffusion of n-type dopants in germanium” [Appl. Phys. Rev. 1, 011301 (2014)

    Energy Technology Data Exchange (ETDEWEB)

    Cowern, N. E. B., E-mail: nick.cowern@ncl.ac.uk; Simdyankin, S.; Goss, J. P. [School of Electrical and Electronic Engineering, Newcastle University, Newcastle upon Tyne NE1 7RU (United Kingdom); Napolitani, E.; De Salvador, D. [CNR-IMM-MATIS and Dipartimento di Fisica, Università di Padova, Via Marzolo 8, 35131 Padova (Italy); Bruno, E.; Mirabella, S. [CNR-IMM-MATIS and Dipartimento di Fisica e Astronomia, Università di Catania, Via S. Sofia 64, 95123 Catania (Italy); Ahn, C. [Samsung Semiconductor, Inc., 3655 North First Street, San Jose, California 95134 (United States); Bennett, N. S. [Institute of Mechanical, Process and Energy Engineering, School of Engineering and Physical Sciences, Heriot-Watt University, Edinburgh EH14 4AS (United Kingdom)

    2015-09-15

    The authors of the above paper call into question recent evidence on the properties of self-interstitials, I, in Ge [Cowern et al., Phys. Rev. Lett. 110, 155501 (2013)]. We show that this judgment stems from invalid model assumptions during analysis of data on B marker-layer diffusion during proton irradiation, and that a corrected analysis fully supports the reported evidence. As previously stated, I-mediated self-diffusion in Ge exhibits two distinct regimes of temperature, T: high-T, dominated by amorphous-like mono-interstitial clusters—i-morphs—with self-diffusion entropy ≈30 k, and low-T, where transport is dominated by simple self-interstitials. In a transitional range centered on 475 °C both mechanisms contribute. The experimental I migration energy of 1.84 ± 0.26 eV reported by the Münster group based on measurements of self-diffusion during irradiation at 550 °C < T < 680 °C further establishes our proposed i-morph mechanism.

  5. Comments on Letter (Phys. Rev. L, Vol.89, No. 10,2002) by D. Shapira and M. Saltmarsh

    CERN Document Server

    Taleyarkhan, Rusi P; Cho, JaeSeon; Lahey, Richard T; Nigmatulin, Robert I; Block, Robert C

    2013-01-01

    This article focuses on correcting several factual errors and critiques in the previously published Letter in Phys. Rev. L, Vol. 89, No. 10, 2022, by D. Shapira and M. Saltmarsh. The authors of the Letter did not perform their own "independent" experiments as claimed; they did not perform control experiments with normal acetone; and, neither did they monitor for tritium. It their Letter, the authors (D. Shapira and M. Saltmarsh) failed to disclose that the data they collected actually confirmed our claims of having observed statistically significant nuclear emissions in chilled, cavitated deuterated acetone.

  6. Quicklook overview of model changes in Melcor 2.2: Rev 6342 to Rev 9496

    Energy Technology Data Exchange (ETDEWEB)

    Humphries, Larry L. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-05-01

    MELCOR 2.2 is a significant official release of the MELCOR code with many new models and model improvements. This report provides the code user with a quick review and characterization of new models added, changes to existing models, the effect of code changes during this code development cycle (rev 6342 to rev 9496), a preview of validation results with this code version. More detailed information is found in the code Subversion logs as well as the User Guide and Reference Manuals.

  7. Horns Rev II, 2-D Model Tests

    DEFF Research Database (Denmark)

    Andersen, Thomas Lykke; Frigaard, Peter

    This report present the results of 2D physical model tests carried out in the shallow wave flume at Dept. of Civil Engineering, Aalborg University (AAU), on behalf of Energy E2 A/S part of DONG Energy A/S, Denmark. The objective of the tests was: to investigate the combined influence of the pile...

  8. Chemistry Teacher Education Coalition: Extending the PhysTEC Model to Chemistry

    Science.gov (United States)

    Kirchhoff, Mary

    2012-02-01

    The American Association of Employment in Education reports that chemistry, like physics, faces ``some shortage'' of educators. Inspired by the success of the Physics Teacher Education Coalition (PhysTEC), the American Chemical Society (ACS) is developing the Chemistry Teacher Education Coalition (CTEC) to actively engage chemistry departments in the preparation of future chemistry teachers. Engaging chemistry departments in teacher preparation would increase the number and diversity of well-prepared high school chemistry teachers while catalyzing cultural change within chemistry departments. Many features of PhysTEC, such as a grant competition to create model teacher preparation programs and regular conferences, are directly applicable to chemistry. This presentation will provide an overview of ACS efforts to launch a successful CTEC initiative.

  9. Erratum: Measurement of transverse single-spin asymmetries for J/psi production in polarized p+p collisions at sqrt(s)=200 GeV [Phys. Rev. D 82, 112008 (2010)

    CERN Document Server

    Adare, A; Aidala, C; Ajitanand, N N; Akiba, Y; Al-Bataineh, H; Alexander, J; Al-Ta'ani, H; Angerami, A; Aoki, K; Apadula, N; Aphecetche, L; Aramaki, Y; Asai, J; Atomssa, E T; Averbeck, R; Awes, T C; Azmoun, B; Babintsev, V; Bai, M; Baksay, G; Baksay, L; Baldisseri, A; Barish, K N; Barnes, P D; Bassalleck, B; Basye, A T; Bathe, S; Batsouli, S; Baublis, V; Baumann, C; Bazilevsky, A; Belikov, S; Belmont, R; Bennett, R; Berdnikov, A; Berdnikov, Y; Bhom, J H; Bickley, A A; Blau, D S; Boissevain, J G; Bok, J S; Borel, H; Borggren, N; Boyle, K; Brooks, M L; Buesching, H; Bumazhnov, V; Bunce, G; Butsyk, S; Camacho, C M; Campbell, S; Caringi, A; Chang, B S; Chang, W C; Charvet, J -L; Chen, C -H; Chernichenko, S; Chi, C Y; Chiu, M; Choi, I J; Choi, J B; Choudhury, R K; Christiansen, P; Chujo, T; Chung, P; Churyn, A; Chvala, O; Cianciolo, V; Citron, Z; Cole, B A; del Valle, Z Conesa; Connors, M; Constantin, P; Csanád, M; Csörgö, T; Dahms, T; Dairaku, S; Danchev, I; Das, K; Datta, A; David, G; Dayananda, M K; Denisov, A; d'Enterria, D; Deshpande, A; Desmond, E J; Dharmawardane, K V; Dietzsch, O; Dion, A; Donadelli, M; Orazio, L D; Drapier, O; Drees, A; Drees, K A; Dubey, A K; Durham, J M; Durum, A; Dutta, D; Dzhordzhadze, V; Edwards, S; Efremenko, Y V; Ellinghaus, F; Engelmore, T; Enokizono, A; En'yo, H; Esumi, S; Eyser, K O; Fadem, B; Fields, D E; Finger,, M; Finger, M; Fleuret, F; Fokin, S L; Fraenkel, Z; Frantz, J E; Franz, A; Frawley, A D; Fujiwara, K; Fukao, Y; Fusayasu, T; Garishvili, I; Glenn, A; Gong, H; Gonin, M; Gosset, J; Goto, Y; de Cassagnac, R Granier; Grau, N; Greene, S V; Grim, G; Perdekamp, M Grosse; Gunji, T; Gustafsson, H -Å; Henni, A Hadj; Haggerty, J S; Hahn, K I; Hamagaki, H; Hamblen, J; Hanks, J; Han, R; Hartouni, E P; Haruna, K; Haslum, E; Hayano, R; Heffner, M; Hemmick, T K; Hester, T; He, X; Hill, J C; Hohlmann, M; Holzmann, W; Homma, K; Hong, B; Horaguchi, T; Hornback, D; Huang, S; Ichihara, T; Ichimiya, R; Iinuma, H; Ikeda, Y; Imai, K; Imrek, J; Inaba, M; Isenhower, D; Ishihara, M; Isobe, T; Issah, M; Isupov, A; Ivanischev, D; Iwanaga, Y; Jia, B V Jacak J; Jiang, X; Jin, J; Johnson, B M; Jones, T; Joo, K S; Jouan, D; Jumper, D S; Kajihara, F; Kametani, S; Kamihara, N; Kamin, J; Kang, J H; Kapustinsky, J; Karatsu, K; Kasai, M; Kawall, D; Kawashima, M; Kazantsev, A V; Kempel, T; Khanzadeev, A; Kijima, K M; Kikuchi, J; Kim, A; Kim, B I; Kim, D H; Kim, D J; Kim, E J; Kim, E; Kim, S H; Kim, Y -J; Kinney, E; Kiriluk, K; Kiss, Á; Kistenev, E; Klay, J; Klein-Boesing, C; Kochenda, L; Komkov, B; Konno, M; Koster, J; Kozlov, A; Král, A; Kravitz, A; Kunde, G J; Kurita, K; Kurosawa, M; Kweon, M J; Kwon, Y; Kyle, G S; Lacey, R; Lai, Y S; Lajoie, J G; Layton, D; Lebedev, A; Lee, D M; Lee, J; Lee, K B; Lee, K S; Lee, T; Leitch, M J; Leite, M A L; Lenzi, B; Lichtenwalner, P; Liebing, P; Levy, L A Linden; Liška, T; Litvinenko, A; Liu, H; Liu, M X; Li, X; Love, B; Lynch, D; Maguire, C F; Makdisi, Y I; Malakhov, A; Malik, M D; Manko, V I; Mannel, E; Mao, Y; Mašek, L; Masui, H; Matathias, F; McCumber, M; McGaughey, P L; Means, N; Meredith, B; Miake, Y; Mibe, T; Mignerey, A C; Mikeš, P; Miki, K; Milov, A; Mishra, M; Mitchell, J T; Mohanty, A K; Moon, H J; Morino, Y; Morreale, A; Morrison, D P; Moukhanova, T V; Mukhopadhyay, D; Murakami, T; Murata, J; Nagamiya, S; Nagle, J L; Naglis, M; Nagy, M I; Nakagawa, I; Nakamiya, Y; Nakamura, K R; Nakamura, T; Nakano, K; Nam, S; Newby, J; Nguyen, M; Nihashi, M; Niita, T; Nouicer, R; Nyanin, A S; Oakley, C; O'Brien, E; Oda, S X; Ogilvie, C A; Okada, K; Oka, M; Onuki, Y; Oskarsson, A; Ouchida, M; Ozawa, K; Pak, R; Palounek, A P T; Pantuev, V; Papavassiliou, V; Park, I H; Park, J; Park, S K; Park, W J; Pate, S F; Pei, H; Peng, J -C; Pereira, H; Peresedov, V; Peressounko, D Yu; Petti, R; Pinkenburg, C; Pisani, R P; Proissl, M; Purschke, M L; Purwar, A K; Qu, H; Rak, J; Rakotozafindrabe, A; Ravinovich, I; Read, K F; Rembeczki, S; Reygers, K; Riabov, V; Riabov, Y; Richardson, E; Roach, D; Roche, G; Rolnick, S D; Rosati, M; Rosen, C A; Rosendahl, S S E; Rosnet, P; Rukoyatkin, P; Ružička, P; Rykov, V L; Sahlmueller, B; Saito, N; Sakaguchi, T; Sakai, S; Sakashita, K; Samsonov, V; Sano, S; Sato, T; Sawada, S; Sedgwick, K; Seele, J; Seidl, R; Semenov, A Yu; Semenov, V; Seto, R; Sharma, D; Shein, I; Shibata, T -A; Shigaki, K; Shimomura, M; Shoji, K; Shukla, P; Sickles, A; Silva, C L; Silvermyr, D; Silvestre, C; Sim, K S; Singh, B K; Singh, C P; Singh, V; Slunečka, M; Soldatov, A; Soltz, R A; Sondheim, W E; Sorensen, S P; Sourikova, I V; Staley, F; Stankus, P W; Stenlund, E; Stepanov, M; Ster, A; Stoll, S P; Sugitate, T; Suire, C; Sukhanov, A; Sziklai, J; Takagui, E M; Taketani, A; Tanabe, R; Tanaka, Y; Taneja, S; Tanida, K; Tannenbaum, M J; Tarafdar, S; Taranenko, A; Tarján, P; Themann, H; Thomas, D; Thomas, T L; Togawa, M; Toia, A; Tomášek, L; Tomita, Y; Torii, H; Towell, R S

    2012-01-01

    We previously reported [Phys. Rev. D 82, 112008 (2010)] measurements of transverse single-spin asymmetries, A_N, in J/psi production from transversely polarized p+p collisions at sqrt(s)=200 GeV with data taken by the PHENIX experiment at the Relativistic Heavy Ion Collider in 2006 and 2008. Subsequently, we have found errors in the analysis procedures for the 2008 data, which resulted in an erroneous value for the extracted A_N. The errors affected the sorting of events into the correct left/right and forward/backward bins. This produced an incorrect value for the 2008 result, but the 2006 result is unaffected. We have conducted two independent reanalyses with these errors corrected, and we present here the corrected values for the 2008 data and the combined results for 2006 and 2008. The new combined spin asymmetry in the forward region is A_N = -0.026+/-0.026(stat)+/-0.003(sys). Since this asymmetry is consistent with zero, we no longer claim that our results suggest a possible non-zero trigluon correlatio...

  10. Structural model of the Rev regulatory protein from equine infectious anemia virus.

    Directory of Open Access Journals (Sweden)

    Yungok Ihm

    Full Text Available Rev is an essential regulatory protein in the equine infectious anemia virus (EIAV and other lentiviruses, including HIV-1. It binds incompletely spliced viral mRNAs and shuttles them from the nucleus to the cytoplasm, a critical prerequisite for the production of viral structural proteins and genomic RNA. Despite its important role in production of infectious virus, the development of antiviral therapies directed against Rev has been hampered by the lack of an experimentally-determined structure of the full length protein. We have used a combined computational and biochemical approach to generate and evaluate a structural model of the Rev protein. The modeled EIAV Rev (ERev structure includes a total of 6 helices, four of which form an anti-parallel four-helix bundle. The first helix contains the leucine-rich nuclear export signal (NES. An arginine-rich RNA binding motif, RRDRW, is located in a solvent-exposed loop region. An ERLE motif required for Rev activity is predicted to be buried in the core of modeled structure where it plays an essential role in stabilization of the Rev fold. This structural model is supported by existing genetic and functional data as well as by targeted mutagenesis of residues predicted to be essential for overall structural integrity. Our predicted structure should increase understanding of structure-function relationships in Rev and may provide a basis for the design of new therapies for lentiviral diseases.

  11. Horns Rev II, 2D-Model Tests

    DEFF Research Database (Denmark)

    Andersen, Thomas Lykke; Brorsen, Michael

    This report present the results of 2D physical model tests carried out in the shallow wave flume at Dept. of Civil Engineering, Aalborg University (AAU), Denmark. The starting point for the present report is the previously carried out run-up tests described in Lykke Andersen & Frigaard, 2006......-shaped access platforms on piles. The Model tests include mainly regular waves and a few irregular wave tests. These tests have been conducted at Aalborg University from 9. November, 2006 to 17. November, 2006....

  12. Horns Rev II, 2D-Model Tests

    DEFF Research Database (Denmark)

    Andersen, Thomas Lykke; Frigaard, Peter

    This report present the results of 2D physical model tests carried out in the shallow wave flume at Dept. of Civil Engineering, Aalborg University (AAU). The objective of the tests was: To investigate the combined influence of the pile diameter to water depth ratio and the wave height to water...... on the front side of the pile (0 to 90 degrees). These tests have been conducted at Aalborg University from 9. October, 2006 to 8. November, 2006. Unless otherwise mentioned, all values given in this report are in model scale....

  13. Specification of advanced safety modeling requirements (Rev. 0).

    Energy Technology Data Exchange (ETDEWEB)

    Fanning, T. H.; Tautges, T. J.

    2008-06-30

    The U.S. Department of Energy's Global Nuclear Energy Partnership has lead to renewed interest in liquid-metal-cooled fast reactors for the purpose of closing the nuclear fuel cycle and making more efficient use of future repository capacity. However, the U.S. has not designed or constructed a fast reactor in nearly 30 years. Accurate, high-fidelity, whole-plant dynamics safety simulations will play a crucial role by providing confidence that component and system designs will satisfy established design limits and safety margins under a wide variety of operational, design basis, and beyond design basis transient conditions. Current modeling capabilities for fast reactor safety analyses have resulted from several hundred person-years of code development effort supported by experimental validation. The broad spectrum of mechanistic and phenomenological models that have been developed represent an enormous amount of institutional knowledge that needs to be maintained. Complicating this, the existing code architectures for safety modeling evolved from programming practices of the 1970s. This has lead to monolithic applications with interdependent data models which require significant knowledge of the complexities of the entire code in order for each component to be maintained. In order to develop an advanced fast reactor safety modeling capability, the limitations of the existing code architecture must be overcome while preserving the capabilities that already exist. To accomplish this, a set of advanced safety modeling requirements is defined, based on modern programming practices, that focuses on modular development within a flexible coupling framework. An approach for integrating the existing capabilities of the SAS4A/SASSYS-1 fast reactor safety analysis code into the SHARP framework is provided in order to preserve existing capabilities while providing a smooth transition to advanced modeling capabilities. In doing this, the advanced fast reactor safety models

  14. Horns Rev II, 2D-Model Tests

    DEFF Research Database (Denmark)

    Andersen, Thomas Lykke; Brorsen, Michael

    This report is an extension of the study presented in Lykke Andersen and Brorsen, 2006 and includes results from the irregular wave tests, where Lykke Andersen & Brorsen, 2006 focused on regular waves. The 2D physical model tests were carried out in the shallow wave flume at Dept. of Civil...

  15. Reference Model 2: %22Rev 0%22 Rotor Design.

    Energy Technology Data Exchange (ETDEWEB)

    Barone, Matthew F.; Berg, Jonathan Charles; Griffith, Daniel

    2011-12-01

    The preliminary design for a three-bladed cross-flow rotor for a reference marine hydrokinetic turbine is presented. A rotor performance design code is described, along with modifications to the code to allow prediction of blade support strut drag as well as interference between two counter-rotating rotors. The rotor is designed to operate in a reference site corresponding to a riverine environment. Basic rotor performance and rigid-body loads calculations are performed to size the rotor elements and select the operating speed range. The preliminary design is verified with a simple finite element model that provides estimates of bending stresses during operation. A concept for joining the blades and support struts is developed and analyzed with a separate finite element analysis. Rotor mass, production costs, and annual energy capture are estimated in order to allow calculations of system cost-of-energy. Evaluation Only. Created with Aspose.Pdf.Kit. Copyright 2002-2011 Aspose Pty Ltd Evaluation Only. Created with Aspose.Pdf.Kit. Copyright 2002-2011 Aspose Pty Ltd

  16. Comment on "A three-loop radiative neutrino mass model with dark matter" [Phys. Lett. B 741 (2015) 163

    CERN Document Server

    Geng, Chao-Qiang; Tsai, Lu-Hsing

    2015-01-01

    We revisit the calculation of the three-loop diagrams for the radiative neutrino mass generation and consider some relevant constraints on the model recently proposed by L. Jin {\\it et al} [Phys. Lett. B 741 (2015) 163]. We find that the previous approximation is inappropriate due to the neglect of some important contributions, and the benchmark point proposed can neither give rise to enough neutrino masses nor accommodate these additional constraints, such as the validity of the perturbation theory, the electroweak precision measurements, and the neutrinoless double beta decays.

  17. Comment on "A new exactly solvable quantum model in $N$ dimensions" [Phys. Lett. A 375(2011)1431, arXiv:1007.1335

    CERN Document Server

    Ley, B L Moreno

    2011-01-01

    We pinpoint that the work about "a new exactly solvable quantum model in $N$ dimensions" by Ballesteros et al. [Phys. Lett. A {\\bf 375} (2011) 1431, arXiv:1007.1335] is not a new exactly solvable quantum model since the flaw of the position-dependent mass Hamiltonian proposed by them makes it less valuable in physics.

  18. Modeling RNA-ligand interactions: the Rev-binding element RNA-aminoglycoside complex.

    Science.gov (United States)

    Leclerc, F; Cedergren, R

    1998-01-15

    An approach to the modeling of ligand-RNA complexes has been developed by combining three-dimensional structure-activity relationship (3D-SAR) computations with a docking protocol. The ability of 3D-SAR to predict bound conformations of flexible ligands was first assessed by attempting to reconstruct the known, bound conformations of phenyloxazolines complexed with human rhinovirus 14 (HRV14) RNA. Subsequently, the same 3D-SAR analysis was applied to the identification of bound conformations of aminoglycosides which associate with the Rev-binding element (RBE) RNA. Bound conformations were identified by parsing ligand conformational data sets with pharmacophores determined by the 3D-SAR analysis. These "bioactive" structures were docked to the receptor RNA, and optimization of the complex was undertaken by extensive searching of ligand conformational space coupled with molecular dynamics computations. The similarity between the bound conformations of the ligand from the 3D-SAR analysis and those found in the docking protocol suggests that this methodology is valid for the prediction of bound ligand conformations and the modeling of the structure of the ligand-RNA complexes.

  19. Numerical modelling of the flow in the resin infusion process on the REV scale: A feasibility study

    DEFF Research Database (Denmark)

    Jabbaribehnam, Mirmasoud; Jambhekar, V. A.; Gersborg, A. R.

    2016-01-01

    development. In this paper, we show the implementation of 2D numerical models for the RIP using the open source simulator DuMuX. The idea of this study is to present a model which accounts for the interfacial forces coming from the capillary pressure on the so-called representative elementary volume (REV......) scale. The model is described in detail and three different test cases - a constant and a tensorial permeability as well as a preform/Balsa domain - are investigated. The results show that the developed model is very applicable for the RIP for manufacturing of composite parts. The idea behind this study...

  20. Soil hydraulic properties and REV study using X-ray microtomography and pore-scale modelling: saturated hydraulic conductivity

    Science.gov (United States)

    Gerke, Kirill; Khirevich, Siarhei; Sizonenko, Timofey; Karsanina, Marina; Umarova, Aminat; Korost, Dmitry; Matthai, Stephan; Mallants, Dirk

    2016-04-01

    To verify pore-scale modelling approach for determination of soil saturated hydraulic conductivity properties we scanned three cylindrical soil samples taken from A, Ah and B horizons using X-ray microtomography method. Resulting 3D soil images with resolutions of 15.25-20.96 μm were segmented into pores and solids and their maximum inscribed cube subvolumes were used as input data for three major pore-scale modelling methods to simulate saturated flow - lattice-Boltzmann method, finite-difference solution of the Stokes problem, and pore-network model. Provided that imaging resolution is high enough to capture the backbone of effective porosity and the main conducting pores all three methods resulted in simulated soil permeabilities close to experimental values for Ah and B samples. The resolution of A sample was not enough for an accurate modelling and we concluded that this soil requires multi-scale imaging to cover all relevant heterogeneities. We demonstrate that popular SWV method to choose segmentation threshold resulted in oversegmentation and order of magnitude higher permeability values. Careful manual thresholding combined with local segmentation algorithm provided much more accurate results. Detailed analysis of water retention curves showed that air-filled porosity at relevant pressure stages cannot be used for verification of the segmentation results. Representativity analysis by simulating flow in increasing soil volume up to 2.8 cm3 revealed no representative elementary volume (REV) within Ah sample and non-uniqueness of REV for B sample. The latter was explained by soil structure non-stationarity. We further speculate that structures soil horizons can exhibit no REV at all. We discuss numerous advantages of coupled imaging and pore-scale modelling approach and show how it can become a successor of the conventional soil coring method to parametrize large scale continuum models.

  1. Numerical Modelling of Large-Diameter Steel Piles at Horns Rev

    DEFF Research Database (Denmark)

    Augustesen, Anders Hust; Brødbæk, K. T.; Møller, M.;

    2009-01-01

    Today large-diameter monopiles are the most common foundation type used for large offshore wind farms. This paper aims to investigate the behaviour of monopiles under monotonic loading taking the interaction between the pile and the subsoil into account. Focus is paid to a monopile used as founda......Today large-diameter monopiles are the most common foundation type used for large offshore wind farms. This paper aims to investigate the behaviour of monopiles under monotonic loading taking the interaction between the pile and the subsoil into account. Focus is paid to a monopile used...... as foundation for a wind turbine at Horns Rev located in the Danish sector of the North Sea. The outer diameter of the pile is 4 m and the subsoil at the location consists primarily of sand. The behaviour of the pile is investigated under realistic loading conditions by means of a traditional Winkler...

  2. Response to "Comment on 'A model for phosphate glass topology considering the modifying ion sub-network"' [J. Chem. Phys. 142, 107103 (2015)].

    Science.gov (United States)

    Hermansen, Christian; Mauro, John C; Yue, Yuanzheng

    2015-03-14

    In our recent paper [C. Hermansen, J. C. Mauro, and Y.-Z. Yue, J. Chem. Phys. 140, 154501 (2014)], we applied temperature-dependent constraint theory to model the glass transition temperature (Tg) and liquid fragility index (m) of alkali phosphate glasses. Sidebottom commented on this paper concerning the m values obtained by differential scanning calorimetry (DSC) [D. L. Sidebottom, J. Chem. Phys. 142, ⬛ (2015)]. We have considered Sidebottom's comments carefully and conclude that the m values of phosphate liquids obtained by DSC are reliable, except for the NaPO3 and possibly P2O5 compositions. Based on his dynamic light scattering measurements, Sidebottom has found that P2O5 is a strong liquid with m ≈ 20. However, based on the heat capacity jump at Tg and the stretching exponent of the relaxation function, P2O5 should be classified as an intermediate fragile liquid with m ≈ 40. We also argue that m cannot be universally related to the average connectivity of the network and point out several inconsistencies with this view.

  3. Numerical modelling of the flow in the resin infusion process on the REV scale: A feasibility study

    Energy Technology Data Exchange (ETDEWEB)

    Jabbari, M.; Spangenberg, J.; Hattel, J. H. [Process Modelling Group, Department of Mechanical Engineering, Technical University of Denmark, Nils Koppels Allé, 2800 Kgs. Lyngby (Denmark); Jambhekar, V. A.; Helmig, R. [Department of Hydromechanics and Modelling of Hydrosystems, Institute for Modelling Hydraulic and Environmental Systems, Universität Stuttgart, Stuttgart (Germany); Gersborg, A. R. [SCION DTU, Diplomvej 373N, DK-2800 Lyngby (Denmark)

    2016-06-08

    The resin infusion process (RIP) has developed as a low cost method for manufacturing large fibre reinforced plastic parts. However, the process still presents some challenges to industry with regards to reliability and repeatability, resulting in expensive and inefficient trial and error development. In this paper, we show the implementation of 2D numerical models for the RIP using the open source simulator DuMu{sup X}. The idea of this study is to present a model which accounts for the interfacial forces coming from the capillary pressure on the so-called representative elementary volume (REV) scale. The model is described in detail and three different test cases — a constant and a tensorial permeability as well as a preform/Balsa domain — are investigated. The results show that the developed model is very applicable for the RIP for manufacturing of composite parts. The idea behind this study is to test the developed model for later use in a real application, in which the preform medium has numerous layers with different material properties.

  4. Numerical modelling of the flow in the resin infusion process on the REV scale: A feasibility study

    Science.gov (United States)

    Jabbari, M.; Jambhekar, V. A.; Gersborg, A. R.; Spangenberg, J.; Hattel, J. H.; Helmig, R.

    2016-06-01

    The resin infusion process (RIP) has developed as a low cost method for manufacturing large fibre reinforced plastic parts. However, the process still presents some challenges to industry with regards to reliability and repeatability, resulting in expensive and inefficient trial and error development. In this paper, we show the implementation of 2D numerical models for the RIP using the open source simulator DuMuX. The idea of this study is to present a model which accounts for the interfacial forces coming from the capillary pressure on the so-called representative elementary volume (REV) scale. The model is described in detail and three different test cases — a constant and a tensorial permeability as well as a preform/Balsa domain — are investigated. The results show that the developed model is very applicable for the RIP for manufacturing of composite parts. The idea behind this study is to test the developed model for later use in a real application, in which the preform medium has numerous layers with different material properties.

  5. Dynamic (G2) Model Design Document, 24590-WTP-MDD-PR-01-002, Rev. 12

    Energy Technology Data Exchange (ETDEWEB)

    Deng, Yueying; Kruger, Albert A.

    2013-12-16

    The Hanford Tank Waste Treatment and Immobilization Plant (WTP) Statement of Work (Department of Energy Contract DE-AC27-01RV14136, Section C) requires the contractor to develop and use process models for flowsheet analyses and pre-operational planning assessments. The Dynamic (G2) Flowsheet is a discrete-time process model that enables the project to evaluate impacts to throughput from eventdriven activities such as pumping, sampling, storage, recycle, separation, and chemical reactions. The model is developed by the Process Engineering (PE) department, and is based on the Flowsheet Bases, Assumptions, and Requirements Document (24590-WTP-RPT-PT-02-005), commonly called the BARD. The terminologies of Dynamic (G2) Flowsheet and Dynamic (G2) Model are interchangeable in this document. The foundation of this model is a dynamic material balance governed by prescribed initial conditions, boundary conditions, and operating logic. The dynamic material balance is achieved by tracking the storage and material flows within the plant as time increments. The initial conditions include a feed vector that represents the waste compositions and delivery sequence of the Tank Farm batches, and volumes and concentrations of solutions in process equipment before startup. The boundary conditions are the physical limits of the flowsheet design, such as piping, volumes, flowrates, operation efficiencies, and physical and chemical environments that impact separations, phase equilibriums, and reaction extents. The operating logic represents the rules and strategies of running the plant.

  6. Chern-Simons term in the 4-dimensional SU(2) Higgs model Rev

    CERN Document Server

    Karsch, Frithjof; Neuhaus, T; Plache, B; Wiese, U J

    1992-01-01

    Using a variation of Lueschers geometric charge definition for SU(2) lattice gauge theory, we have managed to give a geometric expression for it's Chern-Simons ter. From this definition we have checked the periodic structure. we determined the Chern-Simons density for symmetric and asymmetric lattices near the critical region in the SU(2) Higgs model. The data indicate that tunneling is increased at high temperature.

  7. Hanford Soil Inventory Model (SIM) Rev. 1 Software Documentation – Requirements, Design, and Limitations

    Energy Technology Data Exchange (ETDEWEB)

    Simpson, Brett C.; Corbin, Rob A.; Anderson, Michael J.; Kincaid, Charles T.

    2006-09-25

    The objective of this document is to support the simulation results reported by Corbin et al. (2005) by documenting the requirements, conceptual model, simulation methodology, testing, and quality assurance associated with the Hanford Soil Inventory Model (SIM). There is no conventional software life-cycle documentation associated with the Hanford SIM because of the research and development nature of the project. Because of the extensive use of commercial- off-the-shelf software products, there was little actual software development as part of this application. This document is meant to provide historical context and technical support of Corbin et al. (2005), which is a significant revision and update to an earlier product Simpson et al. (2001). The SIM application computed waste discharges composed of 75 analytes at 377 waste sites (liquid disposal, unplanned releases, and tank farm leaks) over an operational period of approximately 50 years. The development and application of SIM was an effort to develop a probabilistic approach to estimate comprehensive, mass balanced-based contaminant inventories for the Hanford Site post-closure setting. A computer model capable of calculating inventories and the associated uncertainties as a function of time was identified to address the needs of the Remediation and Closure Science (RCS) Project.

  8. Comment on ``Unified explanation of the anomalous dynamic properties of highly asymmetric polymer blends'' [J. Chem. Phys. 138, 054903 (2013)

    Science.gov (United States)

    Colmenero, J.

    2013-05-01

    In a recent paper by Ngai and Capaccioli ["Unified explanation of the anomalous dynamic properties of highly asymmetric polymer blends," J. Chem. Phys. 138, 054903 (2013), 10.1063/1.4789585] the authors claimed that the so-called coupling model (CM) provides a unified explanation of all dynamical anomalies that have been reported for dynamically asymmetric blends over last ten years. Approximately half of the paper is devoted to chain-dynamic properties involving un-entangled polymers. According to the authors, the application of the CM to these results is based on the existence of a crossover at a time tc ≈ 1-2 ns of the magnitudes describing chain-dynamics. Ngai and Capaccioli claimed that the existence of such a crossover is supported by the neutron scattering and MD-simulation results, corresponding to the blend poly(methyl methacrylate)/poly(ethylene oxide), by Niedzwiedz et al. [Phys. Rev. Lett. 98, 168301 (2007), 10.1103/PhysRevLett.98.168301] and Brodeck et al. [Macromolecules 43, 3036 (2010), 10.1021/ma902820a], respectively. Being one of the authors of these two papers, I will demonstrate here that there is no evidence supporting such a crossover in the data reported in these papers.

  9. Retraction: On the origin of power-law distributions in systems with constrained phase space [Condens. Matter Phys., 2013, vol. 16, 43802

    Directory of Open Access Journals (Sweden)

    Editorial Board

    2014-03-01

    Full Text Available The article Condens. Matter Phys., 2013, vol. 16, 43802 ( DOI:10.5488/CMP.16.43802 has been retracted by the decision of the Editorial Board. There is a significant overlap with an article: Phys. Rev. E, 2006, vol. 74, 036120 ( DOI:10.1103/PhysRevE.74.036120. Appologies are offered to readers of the journal that this was not detected during the submission process.

  10. Control of the Damped, Driven Pendulum, in both Numerical Models and Physical Apparatus to develop algorithms appropriate to the control chaotic formation of Taylor Vortex Pairs in Modified Taylor-Couette Flow

    Science.gov (United States)

    Douglass, Eric; Zhao, Yunjie; Hill, Lucas; Brenman, David; Olsen, Thomas; Wiener, Richard

    2008-11-01

    Chaos has been observed in the formation of Taylor Vortex pairs in Modified Taylor Couette flow with hourglass geometry. Control of chaos has been demonstrated in this system employing the RPF algorithm. Seeking alternative algorithms, we are implementing the OGY algorithm in a numerical model of a damped driven mechanical pendulum and a physical apparatus. We report on both and future plans for the Modified Taylor-Couette system. Wiener et al, Phys. Rev. E 55, 5489 (1997). Rollins et al, Phys. Rev. E 47, R780 (1993). Wiener et al, Phys. Rev. Lett. 83, 2340 (1999). E. Ott, C. Grebogi, & J. A. Yorke, Phys. Rev. Lett. 64, 1196 (1990). G. L. Baker, Am. J. Phys. 63, 832 (1995). J. A. Blackburn et al, Rev. Sci. Instr. 60, 422 (1989).

  11. Model-based investigation of the circadian clock and cell cycle coupling in mouse embryonic fibroblasts: Prediction of RevErb-α up-regulation during mitosis.

    Science.gov (United States)

    Traynard, Pauline; Feillet, Céline; Soliman, Sylvain; Delaunay, Franck; Fages, François

    2016-11-01

    Experimental observations have put in evidence autonomous self-sustained circadian oscillators in most mammalian cells, and proved the existence of molecular links between the circadian clock and the cell cycle. Some mathematical models have also been built to assess conditions of control of the cell cycle by the circadian clock. However, recent studies in individual NIH3T3 fibroblasts have shown an unexpected acceleration of the circadian clock together with the cell cycle when the culture medium is enriched with growth factors, and the absence of such acceleration in confluent cells. In order to explain these observations, we study a possible entrainment of the circadian clock by the cell cycle through a regulation of clock genes around the mitosis phase. We develop a computational model and a formal specification of the observed behavior to investigate the conditions of entrainment in period and phase. We show that either the selective activation of RevErb-α or the selective inhibition of Bmal1 transcription during the mitosis phase, allow us to fit the experimental data on both period and phase, while a uniform inhibition of transcription during mitosis seems incompatible with the phase data. We conclude on the arguments favoring the RevErb-α up-regulation hypothesis and on some further predictions of the model.

  12. Response to ``Comment on `Optical properties of CdTe1-xSx (0<=x<=1): Experiment and modeling' '' [J. Appl. Phys. 88, 2172 (2000)

    Science.gov (United States)

    Pollak, Fred H.

    2000-08-01

    This communication is a response to the Comment on "Optical properties of CdTeS: Experiment and modeling" by A. B. Djurišić and E. H. Li. The shortcomings of a number of schemes to model the optical constants of diamond- and zincblende-type semiconductors, which do not include continuum exciton effects at either the E0, E0+Δ0 or E1, E1+Δ1 critical points (CPs), are discussed. The Holden model, which has been used to fit the CdTeS data, does include these effects, making it possible to extract important parameters, such as the binding energy of the exciton associated with the E1, E1+Δ1 CPs, not deduced by the other approaches.

  13. Corrigendum to "A novel downscaling technique for the linkage of global and regional air quality modeling" published in Atmos. Chem. Phys., 9, 9169–9185, 2009

    OpenAIRE

    2010-01-01

    Recently, downscaling global atmospheric model outputs (GCTM) for the USEPA Community Multiscale Air Quality (CMAQ) Initial (IC) and Boundary Conditions (BC) have become practical because of the rapid growth of computational technologies that allow global simulations to be completed within a reasonable time. The traditional method of generating IC/BC by profile data has lost its advocates due to the weakness of the limited horizontal and vertical variations found on the gridded boundary layer...

  14. Corrigendum to "A novel downscaling technique for the linkage of global and regional air quality modeling" published in Atmos. Chem. Phys., 9, 9169–9185, 2009

    Directory of Open Access Journals (Sweden)

    Y. F. Lam

    2010-04-01

    Full Text Available Recently, downscaling global atmospheric model outputs (GCTM for the USEPA Community Multiscale Air Quality (CMAQ Initial (IC and Boundary Conditions (BC have become practical because of the rapid growth of computational technologies that allow global simulations to be completed within a reasonable time. The traditional method of generating IC/BC by profile data has lost its advocates due to the weakness of the limited horizontal and vertical variations found on the gridded boundary layers. Theoretically, high quality GCTM IC/BC should yield a better result in CMAQ. Unfortunately, several researchers have found that the outputs from GCTM IC/BC are not necessarily better than profile IC/BC due to the excessive transport of O3 aloft in GCTM IC/BC. In this paper, we intend to investigate the effects of using profile IC/BC and global atmospheric model data. In addition, we are suggesting a novel approach to resolve the existing issue in downscaling.

    In the study, we utilized the GEOS-Chem model outputs to generate time-varied and layer-varied IC/BC for year 2002 with the implementation of tropopause determining algorithm in the downscaling process (i.e., based on chemical (O3 tropopause definition. The comparison between the implemented tropopause approach and the profile IC/BC approach is performed to demonstrate improvement of considering tropopause. It is observed that without using tropopause information in the downscaling process, unrealistic O3 concentrations are created at the upper layers of IC/BC. This phenomenon has caused over-prediction of surface O3 in CMAQ. In addition, the amount of over-prediction is greatly affected by temperature and latitudinal location of the study domain. With the implementation of the algorithm, we have successfully resolved the incompatibility issues in the vertical layer structure between global and regional chemistry models to yield better surface O3

  15. Comment on “A three-loop radiative neutrino mass model with dark matter” [Phys. Lett. B 741 (2015 163

    Directory of Open Access Journals (Sweden)

    Chao-Qiang Geng

    2015-05-01

    Full Text Available We revisit the calculation of the three-loop diagrams for the radiative neutrino mass generation and consider some relevant constraints on the model recently proposed by Jin et al. (2015 [1]. We find that the previous approximation is inappropriate due to the neglect of some important contributions, and the benchmark point proposed can neither give rise to enough neutrino masses nor accommodate these additional constraints, such as the validity of the perturbation theory, the electroweak precision measurements, and the neutrinoless double beta decays.

  16. Three-dimensional multiple-relaxation-time lattice Boltzmann model for convection heat transfer in porous media at the REV scale

    CERN Document Server

    Liu, Q

    2016-01-01

    In this paper, a three-dimensional (3D) multiple-relaxation-time (MRT) lattice Boltzmann (LB) model is presented for convection heat transfer in porous media at the representative elementary volume (REV) scale. The model is developed in the framework of the double-distribution-function (DDF) approach: an MRT-LB model of the density distribution function with the D3Q19 lattice (or D3Q15 lattice) is proposed to simulate the flow field based on the generalized non-Darcy model, while an MRT-LB model of the temperature distribution function with the D3Q7 lattice is proposed to simulate the temperature filed. The present model is employed to simulate mixed convection flow in a porous channel and natural convection in a cubical porous cavity. The numerical results demonstrate the effectiveness and accuracy of the present model in solving 3D convection heat transfer problems in porous media. The numerical results also demonstrate that the present model is approximately second-order accuracy in space. In addition, an ...

  17. Bond-based linear indices of the non-stochastic and stochastic edge-adjacency matrix. 1. Theory and modeling of ChemPhys properties of organic molecules.

    Science.gov (United States)

    Marrero-Ponce, Yovani; Martínez-Albelo, Eugenio R; Casañola-Martín, Gerardo M; Castillo-Garit, Juan A; Echevería-Díaz, Yunaimy; Zaldivar, Vicente Romero; Tygat, Jan; Borges, José E Rodriguez; García-Domenech, Ramón; Torrens, Francisco; Pérez-Giménez, Facundo

    2010-11-01

    Novel bond-level molecular descriptors are proposed, based on linear maps similar to the ones defined in algebra theory. The kth edge-adjacency matrix (E(k)) denotes the matrix of bond linear indices (non-stochastic) with regard to canonical basis set. The kth stochastic edge-adjacency matrix, ES(k), is here proposed as a new molecular representation easily calculated from E(k). Then, the kth stochastic bond linear indices are calculated using ES(k) as operators of linear transformations. In both cases, the bond-type formalism is developed. The kth non-stochastic and stochastic total linear indices are calculated by adding the kth non-stochastic and stochastic bond linear indices, respectively, of all bonds in molecule. First, the new bond-based molecular descriptors (MDs) are tested for suitability, for the QSPRs, by analyzing regressions of novel indices for selected physicochemical properties of octane isomers (first round). General performance of the new descriptors in this QSPR studies is evaluated with regard to the well-known sets of 2D/3D MDs. From the analysis, we can conclude that the non-stochastic and stochastic bond-based linear indices have an overall good modeling capability proving their usefulness in QSPR studies. Later, the novel bond-level MDs are also used for the description and prediction of the boiling point of 28 alkyl-alcohols (second round), and to the modeling of the specific rate constant (log k), partition coefficient (log P), as well as the antibacterial activity of 34 derivatives of 2-furylethylenes (third round). The comparison with other approaches (edge- and vertices-based connectivity indices, total and local spectral moments, and quantum chemical descriptors as well as E-state/biomolecular encounter parameters) exposes a good behavior of our method in this QSPR studies. Finally, the approach described in this study appears to be a very promising structural invariant, useful not only for QSPR studies but also for similarity

  18. Simulation Evidence for Nonlocal Interface Models: Two Correlation Lengths Describe Complete Wetting

    Science.gov (United States)

    Pang, Lijun; Landau, D. P.; Binder, K.

    2011-06-01

    Monte Carlo simulations of (fluctuating) interfaces in Ising models confined between competing walls at temperatures above the wetting transition are presented and various correlation functions probing the interfacial fluctuation are computed. Evidence for the nonlocal interface Hamiltonian approach of A. O. Parry et al. [Phys. Rev. Lett. 93, 086104 (2004)PRLTAO0031-900710.1103/PhysRevLett.93.086104] is given. In particular, we show that two correlation lengths exist with different dependence on the distance D between the walls.

  19. Improved analysis of GW150914 using a fully spin-precessing waveform model

    OpenAIRE

    2016-01-01

    This paper presents updated estimates of source parameters for GW150914, a binary black-hole coalescence event detected by the Laser Interferometer Gravitational-wave Observatory (LIGO) in 2015 [Abbott et al. Phys. Rev. Lett. 116, 061102 (2016).]. Abbott et al. [Phys. Rev. Lett. 116, 241102 (2016).] presented parameter estimation of the source using a 13-dimensional, phenomenological precessing-spin model (precessing IMRPhenom) and an 11-dimensional nonprecessing effective-one-body (EOB) mode...

  20. Conservation laws in the 1 f7 /2 shell model of 48Cr

    Science.gov (United States)

    Neergârd, K.

    2015-04-01

    Conservation laws in the 1 f7 /2 shell model of 48Cr found in numeric studies by Escuderos, Zamick, and Bayman [arXiv:nucl-th/0506050 (2005)] and me [K. Neergård, Phys. Rev. C 90, 014318 (2014) 10.1103/PhysRevC.90.014318] are explained by symmetry under particle-hole conjugation and the structure of the irreps of the symplectic group Sp(4). A generalization is discussed.

  1. Evaluation of the wind direction uncertainty and its impact on wake modeling at the Horns Rev offshore wind farm

    DEFF Research Database (Denmark)

    Gaumond, M.; Réthoré, Pierre-Elouan; Ott, Søren;

    2014-01-01

    of the power deficit in a single wake situation is improved. The robustness of the method is verified using the Jensen model, the Larsen model and Fuga, which are three different engineering wake models. The results indicate that the discrepancies between the traditional numerical simulations and power...... production data for narrow wind direction sectors are not caused by an inherent inaccuracy of the current wake models, but rather by the large wind direction uncertainty included in the dataset. The technique can potentially improve wind farm control algorithms and layout optimization because both...

  2. Suppression of atherosclerosis by synthetic REV-ERB agonist

    Energy Technology Data Exchange (ETDEWEB)

    Sitaula, Sadichha [Department of Molecular Therapeutics, The Scripps Research Institute, Jupiter, FL 33458 (United States); Billon, Cyrielle [Department of Pharmacological & Physiological Science, Saint Louis University School of Medicine, St. Louis, MO 63104 (United States); Kamenecka, Theodore M.; Solt, Laura A. [Department of Molecular Therapeutics, The Scripps Research Institute, Jupiter, FL 33458 (United States); Burris, Thomas P., E-mail: burristp@slu.edu [Department of Pharmacological & Physiological Science, Saint Louis University School of Medicine, St. Louis, MO 63104 (United States)

    2015-05-08

    The nuclear receptors for heme, REV-ERBα and REV-ERBβ, play important roles in the regulation of metabolism and inflammation. Recently it was demonstrated that reduced REV-ERBα expression in hematopoetic cells in LDL receptor null mice led to increased atherosclerosis. We sought to determine if synthetic REV-ERB agonists that we have developed might have the ability to suppress atherosclerosis in this model. A previously characterized synthetic REV-ERB agonist, SR9009, was used to determine if activation of REV-ERB activity would affect atherosclerosis in LDL receptor deficient mice. Atherosclerotic plaque size was significantly reduced (p < 0.05) in mice administered SR9009 (100 mg/kg) for seven weeks compared to control mice (n = 10 per group). SR9009 treatment of bone marrow-derived mouse macrophages (BMDM) reduced the polarization of BMDMs to proinflammatory M1 macrophage while increasing the polarization of BMDMs to anti-inflammatory M2 macrophages. Our results suggest that pharmacological targeting of REV-ERBs may be a viable therapeutic option for treatment of atherosclerosis. - Highlights: • Synthetic REV-ERB agonist treatment reduced atherosclerosis in a mouse model. • Pharmacological activation of REV-ERB decreased M1 macrophage polarization. • Pharmacological activation of REV-ERB increased M2 macrophage polarization.

  3. Numerical modelling of the flow in the resin infusion process on the REV scale: A feasibility study

    DEFF Research Database (Denmark)

    Jabbaribehnam, Mirmasoud; Jambhekar, V. A.; Gersborg, A. R.

    2016-01-01

    The resin infusion process (RIP) has developed as a low cost method for manufacturing large fibre reinforced plastic parts. However, the process still presents some challenges to industry with regards to reliability and repeatability, resulting in expensive and inefficient trial and error......) scale. The model is described in detail and three different test cases - a constant and a tensorial permeability as well as a preform/Balsa domain - are investigated. The results show that the developed model is very applicable for the RIP for manufacturing of composite parts. The idea behind this study...

  4. Rev Variation during Persistent Lentivirus Infection

    Directory of Open Access Journals (Sweden)

    Karin S. Dorman

    2011-01-01

    Full Text Available The ability of lentiviruses to continually evolve and escape immune control is the central impediment in developing an effective vaccine for HIV-1 and other lentiviruses. Equine infectious anemia virus (EIAV is considered a useful model for immune control of lentivirus infection. Virus-specific cytotoxic T lymphocytes (CTL and broadly neutralizing antibody effectively control EIAV replication during inapparent stages of disease, but after years of low-level replication, the virus is still able to produce evasion genotypes that lead to late re-emergence of disease. There is a high rate of genetic variation in the EIAV surface envelope glycoprotein (SU and in the region of the transmembrane protein (TM overlapped by the major exon of Rev. This review examines genetic and phenotypic variation in Rev during EIAV disease and a possible role for Rev in immune evasion and virus persistence.

  5. Expanding the PhysTEC Coalition

    Science.gov (United States)

    Stein, Fredrick

    2003-04-01

    The Physics Teacher Education Coalition (PhysTEC) is a community of physics departments representing scientists and educators at institutions dedicated to improving the science preparation of future K-12 teachers. Now in its second year, PhysTEC requires physics and education faculty to work together to provide an education for future teachers that emphasizes interactive engagement and a student-centered approach to learning science. The first six Coalition members are the physics departments at Ball State University, Oregon State University, University of Arizona, University of Arkansas, Western Michigan University, and Xavier University of Louisiana. PhysTEC is creating a broad, active Coalition of physics departments that have implemented or are interested in implementing one or more of the PhysTEC Program Components. · A long-term, active collaboration among the physics department, the department of education, and the local schools. · A Teacher-in-Residence (TIR) program that provides for a full-time participant in assisting faculty in course revisions. · The redesign of physics courses based on results from physics education research. · The redesign of elementary and secondary science methods courses with an emphasis on inquiry-based teaching and learning. · The establishment of a mentoring program to provide a valuable induction experience for novice science teachers. · The participation of physics faculty in the improvement and expansion of school experiences. www.phystec.org

  6. Hypermutation signature reveals a slippage and realignment model of translesion synthesis by Rev3 polymerase in cisplatin-treated yeast.

    Science.gov (United States)

    Segovia, Romulo; Shen, Yaoqing; Lujan, Scott A; Jones, Steven J M; Stirling, Peter C

    2017-02-21

    Gene-gene or gene-drug interactions are typically quantified using fitness as a readout because the data are continuous and easily measured in high throughput. However, to what extent fitness captures the range of other phenotypes that show synergistic effects is usually unknown. Using Saccharomyces cerevisiae and focusing on a matrix of DNA repair mutants and genotoxic drugs, we quantify 76 gene-drug interactions based on both mutation rate and fitness and find that these parameters are not connected. Independent of fitness defects, we identified six cases of synthetic hypermutation, where the combined effect of the drug and mutant on mutation rate was greater than predicted. One example occurred when yeast lacking RAD1 were exposed to cisplatin, and we characterized this interaction using whole-genome sequencing. Our sequencing results indicate mutagenesis by cisplatin in rad1Δ cells appeared to depend almost entirely on interstrand cross-links at GpCpN motifs. Interestingly, our data suggest that the following base on the template strand dictates the addition of the mutated base. This result differs from cisplatin mutation signatures in XPF-deficient Caenorhabditis elegans and supports a model in which translesion synthesis polymerases perform a slippage and realignment extension across from the damaged base. Accordingly, DNA polymerase ζ activity was essential for mutagenesis in cisplatin-treated rad1Δ cells. Together these data reveal the potential to gain new mechanistic insights from nonfitness measures of gene-drug interactions and extend the use of mutation accumulation and whole-genome sequencing analysis to define DNA repair mechanisms.

  7. TRACKED VEHICLE Rev 75

    Energy Technology Data Exchange (ETDEWEB)

    2007-05-08

    Revision 75 of the Tracked Vehicle software is a soft real-time simulation of a differentially steered, tracked mobile robot, which, because of the track flippers, resembles the iRobot PackBot (http://www.irobot.com/). Open source libraries are used for the physics engine (http://www.ode.org/), the display and user interface (http://www.mathies.com/cpw/), and the program command line and configuration file parameters (http://www.boost.org/). The simulation can be controlled by a USB joystick or the keyboard. The configuration file contains demonstration model parameters of no particular vehicle. This simulation can be used as a starting point for those doing tracked vehicle simulations. This simulation software is essentially a research tool which can be modified and adapted for certain types of tracked vehicle research. An open source license allows an individual researchers to tailor the code to their specific research needs.

  8. Analysis of the virulence-associated RevSR two-component signal transduction system of Clostridium perfringens.

    Science.gov (United States)

    Cheung, Jackie K; Wisniewski, Jessica A; Adams, Vicki M; Quinsey, Noelene S; Rood, Julian I

    2016-09-01

    Clostridium perfringens is a Gram-positive, anaerobic, spore-forming bacterium that causes human gas gangrene (clostridial myonecrosis) and food poisoning. Early studies showed that virulence was regulated by the VirSR two-component signal transduction system. However, our identification of the RevR orphan response regulator indicated that more than one system was involved in controlling virulence. To further characterize this virulence-associated regulator, gel mobility shift experiments, coupled with DNase I footprinting, were used to identify the RevR DNA binding sequence. Bioinformatics analysis suggested that an orphan sensor histidine kinase, CPE1757 (renamed RevS), was the cognate sensor of RevR. Interaction between RevS and RevR was demonstrated by use of a bacterial two-hybrid system and validated by protein-protein interaction studies using biolayer interferometry. To assess the involvement of RevS in virulence regulation, the revS gene was inactivated by Targetron insertion. When isogenic wild-type, revS and complemented revS strains were tested in a mouse myonecrosis model, the revS mutant was found to be attenuated in virulence, which was similar to the attenuation observed previously with the revR mutant. However, transcriptional analysis of selected RevR-regulated genes in the revS mutant revealed a different pattern of expression to a revR mutant, suggesting that the RevSR system is more complex than originally thought. Taken together, the results have led to the identification and characterization of the two essential parts of a new regulatory network that is involved in the regulation of virulence in C. perfringens.

  9. Two-particle correlations via quasi-deterministic analyzer model

    CERN Document Server

    Dalton, B J

    2001-01-01

    We introduce a quasi-deterministic eigenstate transition model of analyzers in which the final eigenstate is selected by initial conditions. We combine this analyzer model with causal spin coupling to calculate both proton-proton and photon-photon correlations, one particle pair at a time. The calculated correlations exceed the Bell limits and show excellent agreement with the measured correlations of [M. Lamehi-Rachti and W. Mittig, Phys. Rev. D 14 (10), 2543 (1976)] and [ A. Aspect, P. Grangier and G. Rogers, Phys. Rev. Lett. 49 91 (1982)] respectively. We discuss why this model exceeds the Bell type limits.

  10. Critical Behaviors in a Stochastic Local Limited One-Dimensional Rice-Pile Model

    Institute of Scientific and Technical Information of China (English)

    SUN Hong-Zhang; TANG Zheng-Xin

    2008-01-01

    A stochastic local fimited one-dimensional rice-pile model is numerically investigated. The distributions for ayalanche sizes have a clear power-law behavior and it displays a simple finite size scaling. We obtain the avalanche exponents Ts = 1.54±0.10, βs = 2.17±0.10 and τT = 1.80±0.10, βT = 1.46±0.10. This self-organized critical model belongs to the same universality class with the Oslo rice-pile model studied by K. Christensen et al. [Phys. Rev. Lett. 77 (1996) 107], a rice-pile model studied by L.A.N. Amaral et al. [Phys. Rev. E 54 (1996) 4512], and a simple deterministic self-organized critical model studied by M.S. Vieira [Phys. Rev. E 61 (2000) 6056].

  11. Nuclear Export Signal Masking Regulates HIV-1 Rev Trafficking and Viral RNA Nuclear Export.

    Science.gov (United States)

    Behrens, Ryan T; Aligeti, Mounavya; Pocock, Ginger M; Higgins, Christina A; Sherer, Nathan M

    2017-02-01

    HIV-1's Rev protein forms a homo-oligomeric adaptor complex linking viral RNAs to the cellular CRM1/Ran-GTP nuclear export machinery through the activity of Rev's prototypical leucine-rich nuclear export signal (NES). In this study, we used a functional fluorescently tagged Rev fusion protein as a platform to study the effects of modulating Rev NES identity, number, position, or strength on Rev subcellular trafficking, viral RNA nuclear export, and infectious virion production. We found that Rev activity was remarkably tolerant of diverse NES sequences, including supraphysiological NES (SNES) peptides that otherwise arrest CRM1 transport complexes at nuclear pores. Rev's ability to tolerate a SNES was both position and multimerization dependent, an observation consistent with a model wherein Rev self-association acts to transiently mask the NES peptide(s), thereby biasing Rev's trafficking into the nucleus. Combined imaging and functional assays also indicated that NES masking underpins Rev's well-known tendency to accumulate at the nucleolus, as well as Rev's capacity to activate optimal levels of late viral gene expression. We propose that Rev multimerization and NES masking regulates Rev's trafficking to and retention within the nucleus even prior to RNA binding.

  12. Erratum: Axion Dark Matter Coupling to Resonant Photons via Magnetic Field [Phys. Rev. Lett. 116, 161804 (2016)

    Science.gov (United States)

    McAllister, Ben T.; Parker, Stephen R.; Tobar, Michael E.

    2016-10-01

    A recent comment highlights a discussion at the PATRAS Workshop on Axions, WIMPs and WISPs relating to a recent publication. We respond to this comment, and detail a calculation error in the original letter.

  13. Erratum: Creation of X-Ray Transparency of Matter by Stimulated Elastic Forward Scattering [Phys. Rev. Lett. 115 , 107402 (2015)

    Energy Technology Data Exchange (ETDEWEB)

    Stöhr, J.; Scherz, A.

    2016-01-06

    X-ray absorption by matter has long been described by the famous Beer-Lambert law. Here we show how this fundamental law needs to be modified for high-intensity coherent x-ray pulses, now available at x-ray free electron lasers, due to the onset of stimulated elastic forward scattering. We present an analytical expression for the modified polarization-dependent Beer-Lambert law for the case of resonant core-to-valence electronic transitions and incident transform limited x-ray pulses. Upon transmission through a solid, the absorption and dichroic contrasts are found to vanish with increasing x-ray intensity, with the stimulation threshold lowered by orders of magnitude through a super-radiative coherent effect. Our results have broad implications for the study of matter with x-ray lasers.

  14. Phase transitions in simplified models with long-range interactions

    Science.gov (United States)

    Rocha Filho, T. M.; Amato, M. A.; Mello, B. A.; Figueiredo, A.

    2011-10-01

    We study the origin of phase transitions in several simplified models with long-range interactions. For the self-gravitating ring model, we are unable to observe a possible phase transition predicted by Nardini and Casetti [Phys. Rev. EPLEEE81539-375510.1103/PhysRevE.80.060103 80, 060103R (2009).] from an energy landscape analysis. Instead we observe a sharp, although without any nonanalyticity, change from a core-halo to a core-only configuration in the spatial distribution functions for low energies. By introducing a different class of solvable simplified models without any critical points in the potential energy we show that a behavior similar to the thermodynamics of the ring model is obtained, with a first-order phase transition from an almost homogeneous high-energy phase to a clustered phase and the same core-halo to core configuration transition at lower energies. We discuss the origin of these features for the simplified models and show that the first-order phase transition comes from the maximization of the entropy of the system as a function of energy and an order parameter, as previously discussed by Hahn and Kastner [Phys. Rev. EPLEEE81539-375510.1103/PhysRevE.72.056134 72, 056134 (2005); Eur. Phys. J. BEPJBFY1434-602810.1140/epjb/e2006-00100-7 50, 311 (2006)], which seems to be the main mechanism causing phase transitions in long-range interacting systems.

  15. 12MW Horns Rev experiment

    DEFF Research Database (Denmark)

    Hasager, Charlotte Bay; Peña, A.; Mikkelsen, Torben

    The 12MW project with the full title ‘12 MW wind turbines: the scientific basis for their operation at 70 to 270 m height offshore’ has the goal to experimentally investigate the wind and turbulence characteristics between 70 and 270 m above sea level and thereby establish the scientific basis...... relevant for the next generation of huge 12 MW wind turbines operating offshore. The report describes the experimental campaign at the Horns Rev offshore wind farm at which observations from Doppler Laser LIDAR and SODAR were collected from 3 May to 24 October 2006. The challenges for mounting...... profile. Further studies on this part of the work are on-going. Technical detail on LIDAR and SODAR are provided as well as theoretical work on turbulence and atmospheric boundary layer flow. Selected results from the experimental campaign are reported....

  16. Applications of Molecular and Materials Modeling

    Science.gov (United States)

    2002-01-01

    nittalabo-e.html Osaka University, Institute for Protein Research Protein modeling Prof. Haruki Nakamura http://www.protein.osaka- u.ac.jp/kessho/members...band structure of YH3. Phys. Rev. B 61, 16491- 16496. Nagashima, U., S. Obara, K. Murakami , T. Yoshii, S. Shirakawa, T. Amisake, K. Kitamura, O. Kitao

  17. ATLAS note ATL-COM-PHYS-2009.

    Energy Technology Data Exchange (ETDEWEB)

    Chekanov, S.; Boomsma, J.; High Energy Physics

    2009-12-22

    The program InvMass has been developed to perform a general model-independent search for new particles using the ATLAS detector at the Large Hadron Collider (LHC), a proton-proton collider at CERN. The search is performed by examining statistically significant variations from the Standard Model predictions in exclusive event classes classified according to the number of identified objects. The program, called InvMass, finds all relevant particle groups identified with the ATLAS detector and analyzes their production rates, invariant masses and the total transverse momenta. The generic code of InvMass can easily be adapted for any particle types identified with the ATLAS detector. Several benchmark tests are presented.

  18. Administrative Circular No. 26 (Rev. 9) – Recognition of Merit

    CERN Multimedia

    2012-01-01

    Administrative Circular No. 26 (Rev. 9) entitled "Recognition of Merit”, approved by the Director-General following discussion in the Standing Concertation Committee meeting on 27 September 2011 is available on the intranet site of the Human Resources Department: https://cern.ch/hr-docs/admincirc/admincirc.asp The circular was above all revised in order to integrate the new CERN Competency Model into the annual procedure of performance appraisal. It cancels and replaces Administrative Circular No. 26 (Rev. 8) entitled "Recognition of merit” of September 2008. Department Head Office HR Department

  19. Scaling of cluster heterogeneity in the two-dimensional Potts model.

    Science.gov (United States)

    Lv, Jian-Ping; Yang, Xianqing; Deng, Youjin

    2012-08-01

    Cluster heterogeneity, the number of clusters of mutually distinct sizes, has been recently studied for explosive percolation and standard percolation [H. K. Lee et al., Phys. Rev. E 84, 020101(R) (2011); J. D. Noh et al., Phys. Rev. E 84, 010101(R) (2011)]. In this work we study the scaling of various quantities related with cluster heterogeneity in a broader context of two-dimensional q-state Potts model. We predict, via an analytic approach, the critical exponents for most of the measured quantities, and confirm these predications for various q values using extensive Monte Carlo simulations.

  20. Multispeed models in off-lattice Boltzmann simulations

    NARCIS (Netherlands)

    Bardow, A.; Karlin, I.V.; Gusev, A.A.

    2008-01-01

    The lattice Boltzmann method is a highly promising approach to the simulation of complex flows. Here, we realize recently proposed multispeed lattice Boltzmann models [S. Chikatamarla et al., Phys. Rev. Lett. 97 190601 (2006)] by exploiting the flexibility offered by off-lattice Boltzmann methods.

  1. Modulated Spin Liquid and Magnetic Order from a Kondo-Heisenberg model applied to $URu_{2}Si_{2}$

    OpenAIRE

    Montiel, Xavier; Burdin, Sébastien; Pépin, Catherine; Ferraz, Alvaro

    2013-01-01

    International audience; Using the Kondo-Heisenberg model framework, we analyze the effect of charge fluctuations in the modulated spin liquid (MSL) and in the antiferromagnetic (AF) ordering which were introduced by Pépin et al. [Phys. Rev. Lett. 106, 106601 (2011)] and Thomas et al. [Phys. Rev. B 87, 014422 (2013)]. Coupling the spin liquid to the charge sector enables us to discuss the formation of the Kondo effect in this system. As a result, we are able to observe the emergence of two pha...

  2. Final Report - Enhanced LAW Glass Property - Composition Models - Phase 1 VSL-13R2940-1, Rev. 0, dated 9/27/2013

    Energy Technology Data Exchange (ETDEWEB)

    Kruger, Albert A.; Muller, I.; Gilbo, K.; Joseph, I.; Pegg, I. L.

    2013-11-13

    The objectives of this work are aimed at the development of enhanced LAW propertycomposition models that expand the composition region covered by the models. The models of interest include PCT, VHT, viscosity and electrical conductivity. This is planned as a multi-year effort that will be performed in phases with the objectives listed below for the current phase.  Incorporate property- composition data from the new glasses into the database.  Assess the database and identify composition spaces in the database that need augmentation.  Develop statistically-designed composition matrices to cover the composition regions identified in the above analysis.  Prepare crucible melts of glass compositions from the statistically-designed composition matrix and measure the properties of interest.  Incorporate the above property-composition data into the database.  Assess existing models against the complete dataset and, as necessary, start development of new models.

  3. Phase II Groundwater Flow Model of Corrective Action Unit 98: Frenchman Flat, Nevada Test Site, Nye County, Nevada, Rev. No.: 0

    Energy Technology Data Exchange (ETDEWEB)

    John McCord

    2006-05-01

    The Phase II Frenchman Flat groundwater flow model is a key element in the ''Federal Facility Agreement and Consent Order'' (FFACO) (1996) corrective action strategy for the Underground Test Area (UGTA) Frenchman Flat corrective action unit (CAU). The objective of this integrated process is to provide an estimate of the vertical and horizontal extent of contaminant migration for each CAU to predict contaminant boundaries. A contaminant boundary is the model-predicted perimeter that defines the extent of radionuclide-contaminated groundwater from underground testing above background conditions exceeding the ''Safe Drinking Water Act'' (SDWA) standards. The contaminant boundary will be composed of both a perimeter boundary and a lower hydrostratigraphic unit (HSU) boundary. The computer model will predict the location of this boundary within 1,000 years and must do so at a 95 percent level of confidence. Additional results showing contaminant concentrations and the location of the contaminant boundary at selected times will also be presented. These times may include the verification period, the end of the five-year proof-of-concept period, as well as other times that are of specific interest. This report documents the development and implementation of the groundwater flow model for the Frenchman Flat CAU. Specific objectives of the Phase II Frenchman Flat flow model are to: (1) Incorporate pertinent information and lessons learned from the Phase I Frenchman Flat CAU models. (2) Develop a three-dimensional (3-D), mathematical flow model that incorporates the important physical features of the flow system and honors CAU-specific data and information. (3) Simulate the steady-state groundwater flow system to determine the direction and magnitude of groundwater fluxes based on calibration to Frenchman Flat hydrogeologic data. (4) Quantify the uncertainty in the direction and magnitude of groundwater flow due to uncertainty in

  4. Meson-Meson Scattering in the Relativistic Quark Model from Constraint Dynamics

    Science.gov (United States)

    Crater, Horace; Wong, Cheuk-Yin

    2004-11-01

    Previously, Crater and Van Alstine footnote H.W. Crater and P. Van Alstine, Ann. Phys. (N.Y.) Vol. 148, 57 (1983) employed Dirac's relativistic constraint dynamics to derive Two-Body Dirac equations which were subsequently applied successfully to obtain a covariant nonperturbative description of QED and QCD bound states footnote H.W. Crater, R.L. Becker, C.Y. Wong, and P. Van Alstine, Phys. Rev. D, Vol.46, 5117 (1992), H. Crater and P. Van Alstine to appear in Phys. Rev. D Vol 70 (hep-ph/0208186). We use this formalism to generalize the microscopic theory of meson-meson scattering developed by Barnes and Swanson footnote T. barnes and E.S. Swanson, Phys. Rev. D Vol. 46, 131 (1992) footnote C.Y. Wong, T. Barnes and E.S. Swanson, Phys. Rev. C Vol 62, 045201 (2001)from the nonrelativistic to the relativistic domain. The application of the present formalism will be demonstrated with a simple quark model for the scattering of mesons.

  5. Phase II Contaminant Transport Parameters for the Groundwater Flow and Contaminant Transport Model of Corrective Action Unit 98: Frenchman Flat, Nye County, Nevada, Rev. No.: 0

    Energy Technology Data Exchange (ETDEWEB)

    DeNovio, Nicole M.; Bryant, Nathan; King, Chrissi B.; Bhark, Eric; Drellack, Sigmund L.; Pickens, John F.; Farnham, Irene; Brooks, Keely M.; Reimus, Paul; Aly, Alaa

    2005-04-01

    This report documents pertinent transport data and data analyses as part of the Phase II Corrective Action Investigation (CAI) for Frenchman Flat (FF) Corrective Action Unit (CAU) 98. The purpose of this data compilation and related analyses is to provide the primary reference to support parameterization of the Phase II FF CAU transport model.

  6. Phase II Hydrologic Data for the Groundwater Flow and Contaminant Transport Model of Corrective Action Unit 98: Frenchman Flat, Nye County, Nevada, Rev. No.: 0

    Energy Technology Data Exchange (ETDEWEB)

    John McCord

    2004-12-01

    This report documents pertinent hydrologic data and data analyses as part of the Phase II Corrective Action Investigation (CAI) for Frenchman Flat (FF) Corrective Action Unit (CAU): CAU 98. The purpose of this data compilation and related analyses is to provide the primary reference to support the development of the Phase II FF CAU groundwater flow model.

  7. Improved Analysis of GW150914 Using a Fully Spin-Precessing Waveform Model

    Science.gov (United States)

    Abbott, B. P.; Abbott, R.; Abbott, T. D.; Abernathy, M. R.; Acernese, F.; Ackley, K.; Adams, C.; Adams, T.; Addesso, P.; Adhikari, R. X.; Adya, V. B.; Affeldt, C.; Agathos, M.; Agatsuma, K.; Aggarwal, N.; Aguiar, O. D.; Aiello, L.; Ain, A.; Ajith, P.; Allen, B.; Allocca, A.; Altin, P. A.; Anderson, S. B.; Anderson, W. G.; Arai, K.; Araya, M. C.; Arceneaux, C. C.; Areeda, J. S.; Arnaud, N.; Arun, K. G.; Ascenzi, S.; Ashton, G.; Ast, M.; Aston, S. M.; Astone, P.; Aufmuth, P.; Aulbert, C.; Babak, S.; Bacon, P.; Bader, M. K. M.; Baker, P. T.; Baldaccini, F.; Ballardin, G.; Ballmer, S. W.; Barayoga, J. C.; Barclay, S. E.; Barish, B. C.; Barker, D.; Barone, F.; Barr, B.; Barsotti, L.; Barsuglia, M.; Barta, D.; Bartlett, J.; Bartos, I.; Bassiri, R.; Basti, A.; Batch, J. C.; Baune, C.; Bavigadda, V.; Bazzan, M.; Bejger, M.; Bell, A. S.; Berger, B. K.; Bergmann, G.; Berry, C. P. L.; Bersanetti, D.; Bertolini, A.; Betzwieser, J.; Bhagwat, S.; Bhandare, R.; Bilenko, I. A.; Billingsley, G.; Birch, J.; Birney, R.; Birnholtz, O.; Biscans, S.; Bisht, A.; Bitossi, M.; Biwer, C.; Bizouard, M. A.; Blackburn, J. K.; Blair, C. D.; Blair, D. G.; Blair, R. M.; Bloemen, S.; Bock, O.; Boer, M.; Bogaert, G.; Bogan, C.; Bohe, A.; Bond, C.; Bondu, F.; Bonnand, R.; Boom, B. A.; Bork, R.; Boschi, V.; Bose, S.; Bouffanais, Y.; Bozzi, A.; Bradaschia, C.; Brady, P. R.; Braginsky, V. B.; Branchesi, M.; Brau, J. E.; Briant, T.; Brillet, A.; Brinkmann, M.; Brisson, V.; Brockill, P.; Broida, J. E.; Brooks, A. F.; Brown, D. A.; Brown, D. D.; Brown, N. M.; Brunett, S.; Buchanan, C. C.; Buikema, A.; Bulik, T.; Bulten, H. J.; Buonanno, A.; Buskulic, D.; Buy, C.; Byer, R. L.; Cabero, M.; Cadonati, L.; Cagnoli, G.; Cahillane, C.; Calderón Bustillo, J.; Callister, T.; Calloni, E.; Camp, J. B.; Cannon, K. C.; Cao, J.; Capano, C. D.; Capocasa, E.; Carbognani, F.; Caride, S.; Casanueva Diaz, C.; Casentini, J.; Caudill, S.; Cavaglià, M.; Cavalier, F.; Cavalieri, R.; Cella, G.; Cepeda, C. B.; Cerboni Baiardi, L.; Cerretani, G.; Cesarini, E.; Chamberlin, S. J.; Chan, M.; Chao, S.; Charlton, P.; Chassande-Mottin, E.; Cheeseboro, B. D.; Chen, H. Y.; Chen, Y.; Cheng, C.; Chincarini, A.; Chiummo, A.; Cho, H. S.; Cho, M.; Chow, J. H.; Christensen, N.; Chu, Q.; Chua, S.; Chung, S.; Ciani, G.; Clara, F.; Clark, J. A.; Cleva, F.; Coccia, E.; Cohadon, P.-F.; Colla, A.; Collette, C. G.; Cominsky, L.; Constancio, M.; Conte, A.; Conti, L.; Cook, D.; Corbitt, T. R.; Cornish, N.; Corsi, A.; Cortese, S.; Costa, C. A.; Coughlin, M. W.; Coughlin, S. B.; Coulon, J.-P.; Countryman, S. T.; Couvares, P.; Cowan, E. E.; Coward, D. M.; Cowart, M. J.; Coyne, D. C.; Coyne, R.; Craig, K.; Creighton, J. D. E.; Cripe, J.; Crowder, S. G.; Cumming, A.; Cunningham, L.; Cuoco, E.; Dal Canton, T.; Danilishin, S. L.; D'Antonio, S.; Danzmann, K.; Darman, N. S.; Dasgupta, A.; Da Silva Costa, C. F.; Dattilo, V.; Dave, I.; Davier, M.; Davies, G. S.; Daw, E. J.; Day, R.; De, S.; DeBra, D.; Debreczeni, G.; Degallaix, J.; De Laurentis, M.; Deléglise, S.; Del Pozzo, W.; Denker, T.; Dent, T.; Dergachev, V.; De Rosa, R.; DeRosa, R. T.; DeSalvo, R.; Devine, R. C.; Dhurandhar, S.; Díaz, M. C.; Di Fiore, L.; Di Giovanni, M.; Di Girolamo, T.; Di Lieto, A.; Di Pace, S.; Di Palma, I.; Di Virgilio, A.; Dolique, V.; Donovan, F.; Dooley, K. L.; Doravari, S.; Douglas, R.; Downes, T. P.; Drago, M.; Drever, R. W. P.; Driggers, J. C.; Ducrot, M.; Dwyer, S. E.; Edo, T. B.; Edwards, M. C.; Effler, A.; Eggenstein, H.-B.; Ehrens, P.; Eichholz, J.; Eikenberry, S. S.; Engels, W.; Essick, R. C.; Etienne, Z.; Etzel, T.; Evans, M.; Evans, T. M.; Everett, R.; Factourovich, M.; Fafone, V.; Fair, H.; Fairhurst, S.; Fan, X.; Fang, Q.; Farinon, S.; Farr, B.; Farr, W. M.; Fauchon-Jones, E.; Favata, M.; Fays, M.; Fehrmann, H.; Fejer, M. M.; Fenyvesi, E.; Ferrante, I.; Ferreira, E. C.; Ferrini, F.; Fidecaro, F.; Fiori, I.; Fiorucci, D.; Fisher, R. P.; Flaminio, R.; Fletcher, M.; Fournier, J.-D.; Frasca, S.; Frasconi, F.; Frei, Z.; Freise, A.; Frey, R.; Frey, V.; Fritschel, P.; Frolov, V. V.; Fulda, P.; Fyffe, M.; Gabbard, H. A. G.; Gaebel, S.; Gair, J. R.; Gammaitoni, L.; Gaonkar, S. G.; Garufi, F.; Gaur, G.; Gehrels, N.; Gemme, G.; Geng, P.; Genin, E.; Gennai, A.; George, J.; Gergely, L.; Germain, V.; Ghosh, Abhirup; Ghosh, Archisman; Ghosh, S.; Giaime, J. A.; Giardina, K. D.; Giazotto, A.; Gill, K.; Glaefke, A.; Goetz, E.; Goetz, R.; Gondan, L.; González, G.; Gonzalez Castro, J. M.; Gopakumar, A.; Gordon, N. A.; Gorodetsky, M. L.; Gossan, S. E.; Gosselin, M.; Gouaty, R.; Grado, A.; Graef, C.; Graff, P. B.; Granata, M.; Grant, A.; Gras, S.; Gray, C.; Greco, G.; Green, A. C.; Groot, P.; Grote, H.; Grunewald, S.; Guidi, G. M.; Guo, X.; Gupta, A.; Gupta, M. K.; Gushwa, K. E.; Gustafson, E. K.; Gustafson, R.; Hacker, J. J.

    2016-10-01

    This paper presents updated estimates of source parameters for GW150914, a binary black-hole coalescence event detected by the Laser Interferometer Gravitational-wave Observatory (LIGO) in 2015 [Abbott et al. Phys. Rev. Lett. 116, 061102 (2016).]. Abbott et al. [Phys. Rev. Lett. 116, 241102 (2016).] presented parameter estimation of the source using a 13-dimensional, phenomenological precessing-spin model (precessing IMRPhenom) and an 11-dimensional nonprecessing effective-one-body (EOB) model calibrated to numerical-relativity simulations, which forces spin alignment (nonprecessing EOBNR). Here, we present new results that include a 15-dimensional precessing-spin waveform model (precessing EOBNR) developed within the EOB formalism. We find good agreement with the parameters estimated previously [Abbott et al. Phys. Rev. Lett. 116, 241102 (2016).], and we quote updated component masses of 35-3+5 M⊙ and 3 0-4+3 M⊙ (where errors correspond to 90% symmetric credible intervals). We also present slightly tighter constraints on the dimensionless spin magnitudes of the two black holes, with a primary spin estimate <0.65 and a secondary spin estimate <0.75 at 90% probability. Abbott et al. [Phys. Rev. Lett. 116, 241102 (2016).] estimated the systematic parameter-extraction errors due to waveform-model uncertainty by combining the posterior probability densities of precessing IMRPhenom and nonprecessing EOBNR. Here, we find that the two precessing-spin models are in closer agreement, suggesting that these systematic errors are smaller than previously quoted.

  8. Charged BPS vortices and reversal of the magnetic flux in a Maxwell-Higgs type model without the Chern-Simons term

    Energy Technology Data Exchange (ETDEWEB)

    Cantanhede, Carlisson M. [Instituto de Fisica Teorica (IFT/UNESP), Sao Paulo, SP (Brazil); Casana, Rodolfo; Ferreira Junior, Manoel M. [Universidade Federal do Maranhao (UFMA), MA (Brazil). Dept. de Fisica; Hora, Eduardo da [Universidade Federal da Paraiba (UFPB), PB (Brazil). Dept. de Fisica

    2012-07-01

    Full text: Since the seminal works by Abrikosov [1] and Nielsen-Olesen [2] showing the existence of uncharged vortex, such nonperturbative solutions have been a theoretical issue of enduring interest. Already, the electrically charged vortices are obtained only in abelian models endowed with the Chern-Simons term [3,4]. This remains valid even in the context of highly nonlinear models, such as the Born-Infield electrodynamics. In this work, we demonstrated the existence of electrically charged BPS vortices in a Maxwell-Higgs model without the Chern- Simons term but endowed with a CPT-even and parity-odd Lorentz-violating (LV) structure. The LV term belonging to the CPT-even electrodynamics of the Standard Model Extension [5] plays a similar role that of the Chern-Simons term, mixing the electric and magnetic sectors. Besides the LV coefficients provide a very rich set of vortex configurations exhibiting electric's field inversion also are responsible by controlling the characteristic length of the vortex and by the flipping of the magnetic flux. [1] A. Abrikosov, Sov. Phys. JETP 32, 1442 (1957). [2] H. Nielsen, P. Olesen, Nucl. Phys. B 61, 45 (1973). [3] R. Jackiw and E. J. Weinberg, Phys. Rev. Lett. 64, 2234 (1990). [4] C.K. Lee, K.M. Lee, H. Min, Phys. Lett. B 252, 79 (1990) [5] D. Colladay and V. A. Kostelecky, Phys. Rev. D 55, 6760 (1997); Phys. Rev. D 58, 116002 (1998). (author)

  9. Safety analysis report for packaging, Oak Ridge Y-12 Plant, model DC-1 package with HEU oxide contents. Change pages for Rev.1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-01-18

    This Safety Analysis Report for Packaging for the Oak Ridge Y-12 Plant for the Model DC-1 package with highly enriched uranium (HEU) oxide contents has been prepared in accordance with governing regulations form the Nuclear Regulatory Commission and the Department of Transportation and orders from the Department of energy. The fundamental safety requirements addressed by these regulations and orders pertain to the containment of radioactive material, radiation shielding, and nuclear subcriticality. This report demonstrates how these requirements are met.

  10. Point Processes Modeling of Time Series Exhibiting Power-Law Statistics

    CERN Document Server

    Kaulakys, B; Gontis, V

    2010-01-01

    We consider stochastic point processes generating time series exhibiting power laws of spectrum and distribution density (Phys. Rev. E 71, 051105 (2005)) and apply them for modeling the trading activity in the financial markets and for the frequencies of word occurrences in the language.

  11. Dynamics of the 1D Heisenberg model and optical absorption of spinons in cuprate antiferromagnetic chains

    NARCIS (Netherlands)

    Lorenzana, J.; Eder, R.

    1996-01-01

    Published in: Phys. Rev. B 55 (1997) 3358-3361 Citing articles (CrossRef) citations recorded in [Science Citation Index] Abstract: We use numerical and analytical results to construct a simple ansatz for the energy dynamical correlation function of the 1D antiferromagnetic Heisenberg model. This is

  12. Numerical Simulation of the Two-State Decoherence Model of Nano-Spin Systems

    Institute of Scientific and Technical Information of China (English)

    蒋永进; 陶瑞宝

    2002-01-01

    We have studied the two-state random decoherence model of the V15 system (Phys. Rev. Lett. 84 (2000) 3458)time and the random dipolar interaction amplitude is verified. The distribution function of decoherence timespreads more widely as the amplitude of the random field is decreased, hence it is dirficult to define a decoherencetime for the system.

  13. Non-perturbative model for the half-off-shell $gamma N N$ vertex

    NARCIS (Netherlands)

    Kondratyuk, S.; Scholten, O.

    1999-01-01

    Submitted to: Phys. Rev. C Abstract: Form factors in the nucleon-photon vertex with one off-shell nucleon are calculated by dressing the vertex with pion loops up to infinite order. Cutting rules and dispersion relations are implemented in the model. Using the prescription of minimal substitution we

  14. Stratification issues in the primary system. Review of available validation experiments and State-of-the-Art in modelling capabilities (StratRev)

    Energy Technology Data Exchange (ETDEWEB)

    Westin, J.; Henriksson, M. (Vattenfall Research and Development AB (Sweden)); Paettikangas, T. (VTT (Finland)); Toppila, T.; Raemae, T. (Fortum Nuclear Services Ltd (Finland)); Kudinov, P. (KTH Nuclear Power Safety (Sweden)); Anglart, H. (KTH Nuclear Reactor Technology (Sweden))

    2009-08-15

    The objective of the present report is to review available validation experiments and State-of-the-Art in modelling of stratification and mixing in the primary system of Light Water Reactors. A topical workshop was arranged in AElvkarleby in June 2008 within the framework of BWR-OG, and the presentations from various utilities showed that stratification issues are not unusual and can cause costly stops in the production. It is desirable to take actions in order to reduce the probability for stratification to occur, and to develop well-validated and accepted tools and procedures for analyzing upcoming stratification events. A research plan covering the main questions is outlined, and a few suggestions regarding more limited research activities are given. Since many of the stratification events results in thermal loads that are localized in time and space, CFD is a suitable tool. However, the often very large and complex geometry posses a great challenge to CFD, and it is important to perform a step-by-step increase in complexity with intermediate validation versus relevant experimental data. The ultimate goal is to establish Best Practice Guidelines that can be followed both by utilities and authorities in case of an event including stratification and thermal loads. An extension of the existing Best Practice Guidelines for CFD in nuclear safety applications developed by OECD/NEA is thus suggested as a relevant target for a continuation project. (au)

  15. Molecular interaction between K-Ras and H-REV107 in the Ras signaling pathway.

    Science.gov (United States)

    Han, Chang Woo; Jeong, Mi Suk; Jang, Se Bok

    2017-09-16

    Ras proteins are small GTPases that serve as master moderators of a large number of signaling pathways involved in various cellular processes. Activating mutations in Ras are found in about one-third of cancers. H-REV107, a K-Ras binding protein, plays an important role in determining K-Ras function. H-REV107 is a member of the HREV107 family of class II tumor suppressor genes and a growth inhibitory Ras target gene that suppresses cellular growth, differentiation, and apoptosis. Expression of H-REV107 was strongly reduced in about 50% of human carcinoma cell lines. However, the specific molecular mechanism by which H-REV107 inhibits Ras is still unknown. In the present study, we suggest that H-REV107 forms a strong complex with activating oncogenic mutation Q61H K-Ras from various biochemical binding assays and modeled structures. In addition, the interaction sites between K-Ras and H-REV107 were predicted based on homology modeling. Here, we found that some structure-based mutants of the K-Ras disrupted the complex formation with H-REV107. Finally, a novel molecular mechanism describing K-Ras and H-REV107 binding is suggested and insights into new K-Ras effector target drugs are provided. Copyright © 2017 Elsevier Inc. All rights reserved.

  16. Research-based resources on PhysPort

    Science.gov (United States)

    Sayre, Eleanor

    2017-01-01

    PhysPort (http://physport.org) is a website that supports physics faculty in implementing research-based teaching practices in their classrooms. We provide expert recommendations and practical information about teaching methods and assessment. The PhysPort Data Explorer is an intuitive online tool for physics faculty to analyze their assessment data. Faculty upload their students' responses using our secure interface. The Data Explorer matches their pre/post data, scores it, compares it to national data, and graphs it in an interactive and intuitive manner. The Periscope collection on Physport brings together classroom video of students working groups with professional development materials for faculty, pre-service teachers, and learning assistants. To support PhysPort's development efforts, we conduct research on faculty needs around teaching and assessment, secondary analysis of published PER studies, and primary analysis of assessment data. In this talk, I'll introduce some of PhysPort's research-based resources and the research results which support them.

  17. Improved lattice Boltzmann modeling of binary flow based on the conservative Allen-Cahn equation

    Science.gov (United States)

    Ren, Feng; Song, Baowei; Sukop, Michael C.; Hu, Haibao

    2016-08-01

    The primary and key task of binary fluid flow modeling is to track the interface with good accuracy, which is usually challenging due to the sharp-interface limit and numerical dispersion. This article concentrates on further development of the conservative Allen-Cahn equation (ACE) [Geier et al., Phys. Rev. E 91, 063309 (2015), 10.1103/PhysRevE.91.063309] under the framework of the lattice Boltzmann method (LBM), with incorporation of the incompressible hydrodynamic equations [Liang et al., Phys. Rev. E 89, 053320 (2014), 10.1103/PhysRevE.89.053320]. Utilizing a modified equilibrium distribution function and an additional source term, this model is capable of correctly recovering the conservative ACE through the Chapman-Enskog analysis. We also simulate four phase-tracking benchmark cases, including one three-dimensional case; all show good accuracy as well as low numerical dispersion. By coupling the incompressible hydrodynamic equations, we also simulate layered Poiseuille flow and the Rayleigh-Taylor instability, illustrating satisfying performance in dealing with complex flow problems, e.g., high viscosity ratio, high density ratio, and high Reynolds number situations. The present work provides a reliable and efficient solution for binary flow modeling.

  18. HIV Rev Assembly on the Rev Response Element (RRE: A Structural Perspective

    Directory of Open Access Journals (Sweden)

    Jason W. Rausch

    2015-06-01

    Full Text Available HIV-1 Rev is an ~13 kD accessory protein expressed during the early stage of virus replication. After translation, Rev enters the nucleus and binds the Rev response element (RRE, a ~350 nucleotide, highly structured element embedded in the env gene in unspliced and singly spliced viral RNA transcripts. Rev-RNA assemblies subsequently recruit Crm1 and other cellular proteins to form larger complexes that are exported from the nucleus. Once in the cytoplasm, the complexes dissociate and unspliced and singly-spliced viral RNAs are packaged into nascent virions or translated into viral structural proteins and enzymes, respectively. Rev binding to the RRE is a complex process, as multiple copies of the protein assemble on the RNA in a coordinated fashion via a series of Rev-Rev and Rev-RNA interactions. Our understanding of the nature of these interactions has been greatly advanced by recent studies using X-ray crystallography, small angle X-ray scattering (SAXS and single particle electron microscopy as well as biochemical and genetic methodologies. These advances are discussed in detail in this review, along with perspectives on development of antiviral therapies targeting the HIV-1 RRE.

  19. Full density-matrix numerical renormalization group calculation of impurity susceptibility and specific heat of the Anderson impurity model

    Science.gov (United States)

    Merker, L.; Weichselbaum, A.; Costi, T. A.

    2012-08-01

    Recent developments in the numerical renormalization group (NRG) allow the construction of the full density matrix (FDM) of quantum impurity models [see A. Weichselbaum and J. von Delft, Phys. Rev. Lett.PRLTAO0031-900710.1103/PhysRevLett.99.076402 99, 076402 (2007)] by using the completeness of the eliminated states introduced by F. B. Anders and A. Schiller [F. B. Anders and A. Schiller, Phys. Rev. Lett.PRLTAO0031-900710.1103/PhysRevLett.95.196801 95, 196801 (2005)]. While these developments prove particularly useful in the calculation of transient response and finite-temperature Green's functions of quantum impurity models, they may also be used to calculate thermodynamic properties. In this paper, we assess the FDM approach to thermodynamic properties by applying it to the Anderson impurity model. We compare the results for the susceptibility and specific heat to both the conventional approach within NRG and to exact Bethe ansatz results. We also point out a subtlety in the calculation of the susceptibility (in a uniform field) within the FDM approach. Finally, we show numerically that for the Anderson model, the susceptibilities in response to a local and a uniform magnetic field coincide in the wide-band limit, in accordance with the Clogston-Anderson compensation theorem.

  20. Experimental three-dimensional beam profiling and modeling of a terahertz beam generated from a two-color air plasma

    DEFF Research Database (Denmark)

    Pedersen, Pernille Klarskov; Strikwerda, Andrew; Iwaszczuk, Krzysztof

    2013-01-01

    in the focal region, and the transition from the donut profile to a central peak is consistent with propagation of a Bessel–Gauss beam, as shown by simulations based on a recent transient photocurrent model (You et al 2012 Phys. Rev. Lett. 109 183902). We combine our measurements to the first full 3D...

  1. Exact solutions of the high dimensional hard-core Fermi-Hubbard model

    Institute of Scientific and Technical Information of China (English)

    PAN; Feng

    2001-01-01

    [1]Hubbard, J., Electron correlations in narrow energy bands, Proc. R. Soc. London, A, 963, 276: 238.[2]Hubbard, J., Electron correlations in narrow energy bands II. The degenerate band case, Proc. R. Soc. London A, 963, A277: 237.[3]Anderson, P. W., The resonating valence bond state in La2CuOand superconductivity, Science, 987, 235: 96.[4]Lieb, E. H, Wu, F. Y., Absence of Mott transition in an exact solution of the short-range one-band model in one dimension, Phys. Rev. Lett., 968, 20: 445.[5]Ogata, M., Shiba, H., Bethe-ansatz wave function, momentum distribution, and spin correlation in the one-dimensional strongly correlated Hubbard model, Phys. Rev., 990, B4: 326.[6]Ogata, M., Sugiyama, T., Shiba, H., Magnetic-field effects on the correlation functions in the one-dimensional strongly correlated Hubbard model, Phys. Rev., 990, B43: 840.[7]Mei, C., Chen, L., Study of the interaction between two electrons in the single band Hubbard model, Z. Phys., 988, B72: 429.[8]Caspers, W. J., Iske, P. L., Exact spectrum for n electrons in the single band Hubbard model, Physica, 989, A, 57: 033.[9]Kirson, M. W., A dynamical supersymmetry in the Hubbard model, Phys. Rev. Lett., 997, 78: 24.[10]Woynarovich, F., Excitations with complex wavefunctions in a Hubbard chain: II. States with several pairs of complex wavenumbers, J. Phys., 982, C5: 97.

  2. Revised Safety Instruction 4 (IS4 REV.)

    CERN Multimedia

    2006-01-01

    Please note that the revised safety instruction 4 (IS4 REV.) entitled 'Safety Inspections' is available on the web at the following url: https://edms.cern.ch/file/335741/LAST_RELEASED/E_IS4.pdf Paper copies can also be obtained from the SC unit secretariat, e-mail: sc.secretariat@cern.ch SC Secretariat

  3. Nuclear Factor 90, a cellular dsRNA binding protein inhibits the HIV Rev-export function

    Directory of Open Access Journals (Sweden)

    St-Laurent Georges

    2006-11-01

    Full Text Available Abstract Background The HIV Rev protein is known to facilitate export of incompletely spliced and unspliced viral transcripts to the cytoplasm, a necessary step in virus life cycle. The Rev-mediated nucleo-cytoplasmic transport of nascent viral transcripts, dependents on interaction of Rev with the RRE RNA structural element present in the target RNAs. The C-terminal variant of dsRNA-binding nuclear protein 90 (NF90ctv has been shown to markedly attenuate viral replication in stably transduced HIV-1 target cell line. Here we examined a mechanism of interference of viral life cycle involving Rev-NF90ctv interaction. Results Since Rev:RRE complex formations depend on protein:RNA and protein:protein interactions, we investigated whether the expression of NF90ctv might interfere with Rev-mediated export of RRE-containing transcripts. When HeLa cells expressed both NF90ctv and Rev protein, we observed that NF90ctv inhibited the Rev-mediated RNA transport. In particular, three regions of NF90ctv protein are involved in blocking Rev function. Moreover, interaction of NF90ctv with the RRE RNA resulted in the expression of a reporter protein coding sequences linked to the RRE structure. Moreover, Rev influenced the subcellular localization of NF90ctv, and this process is leptomycin B sensitive. Conclusion The dsRNA binding protein, NF90ctv competes with HIV Rev function at two levels, by competitive protein:protein interaction involving Rev binding to specific domains of NF90ctv, as well as by its binding to the RRE-RNA structure. Our results are consistent with a model of Rev-mediated HIV-1 RNA export that envisions Rev-multimerization, a process interrupted by NF90ctv.

  4. Analytical Validation of a Continuum Model for Epitaxial Growth with Elasticity on Vicinal Surfaces

    Science.gov (United States)

    Dal Maso, G.; Fonseca, I.; Leoni, G.

    2014-06-01

    Within the context of heteroepitaxial growth of a film onto a substrate, terraces and steps self-organize according to misfit elasticity forces. Discrete models of this behavior were developed by Duport et al. (J Phys I 5:1317-1350, 1995) and Tersoff et al. (Phys Rev Lett 75:2730-2733, 1995). A continuum limit of these was in turn derived by Xiang (SIAM J Appl Math 63:241-258, 2002) (see also the work of Xiang and Weinan Phys Rev B 69:035409-1-035409-16, 2004; Xu and Xiang SIAM J Appl Math 69:1393-1414, 2009). In this paper we formulate a notion of weak solution to Xiang's continuum model in terms of a variational inequality that is satisfied by strong solutions. Then we prove the existence of a weak solution.

  5. Thermodynamics of Rev-RNA interactions in HIV-1 Rev-RRE assembly.

    Science.gov (United States)

    Jayaraman, Bhargavi; Mavor, David; Gross, John D; Frankel, Alan D

    2015-10-27

    The HIV-1 protein Rev facilitates the nuclear export of intron-containing viral mRNAs by recognizing a structured RNA site, the Rev-response-element (RRE), contained in an intron. Rev assembles as a homo-oligomer on the RRE using its α-helical arginine-rich-motif (ARM) for RNA recognition. One unique feature of this assembly is the repeated use of the ARM from individual Rev subunits to contact distinct parts of the RRE in different binding modes. How the individual interactions differ and how they contribute toward forming a functional complex is poorly understood. Here we examine the thermodynamics of Rev-ARM peptide binding to two sites, RRE stem IIB, the high-affinity site that nucleates Rev assembly, and stem IA, a potential intermediate site during assembly, using NMR spectroscopy and isothermal titration calorimetry (ITC). NMR data indicate that the Rev-IIB complex forms a stable interface, whereas the Rev-IA interface is highly dynamic. ITC studies show that both interactions are enthalpy-driven, with binding to IIB being 20-30 fold tighter than to IA. Salt-dependent decreases in affinity were similar at both sites and predominantly enthalpic in nature, reflecting the roles of electrostatic interactions with arginines. However, the two interactions display strikingly different partitioning between enthalpy and entropy components, correlating well with the NMR observations. Our results illustrate how the variation in binding modes to different RRE target sites may influence the stability or order of Rev-RRE assembly and disassembly, and consequently its function.

  6. REV-ERB and ROR: therapeutic targets for treating myopathies

    Science.gov (United States)

    Welch, Ryan D.; Flaveny, Colin A.

    2017-08-01

    Muscle is primarily known for its mechanical roles in locomotion, maintenance of posture, and regulation of cardiac and respiratory function. There are numerous medical conditions that adversely affect muscle, myopathies that disrupt muscle development, regeneration and protein turnover to detrimental effect. Skeletal muscle is also a vital secretory organ that regulates thermogenesis, inflammatory signaling and directs context specific global metabolic changes in energy substrate preference on a daily basis. Myopathies differ in the causative factors that drive them but share common features including severe reduction in quality of life and significantly increased mortality all due irrefutably to the loss of muscle mass. Thus far clinically viable approaches for preserving muscle proteins and stimulating new muscle growth without unwanted side effects or limited efficacy has been elusive. Over the last few decades, evidence has emerged through in vitro and in vivo studies that suggest the nuclear receptors REV-ERB and ROR might modulate pathways involved in myogenesis and mitochondrial biogenesis. Hinting that REV-ERB and ROR might be targeted to treat myopathies. However there is still a need for substantial investigation into the roles of these nuclear receptors in in vivo rodent models of degenerative muscle diseases and acute injury. Although exciting, REV-ERB and ROR have somewhat confounding roles in muscle physiology and therefore more studies utilizing in vivo models of skeletal muscle myopathies are needed. In this review we highlight the molecular forces driving some of the major degenerative muscular diseases and showcase two promising molecular targets that may have the potential to treat myopathies: ROR and REV-ERB.

  7. Epistatic participation of REV1 and REV3 in the formation of UV-induced frameshift mutations in cell cycle-arrested yeast cells

    Energy Technology Data Exchange (ETDEWEB)

    Heidenreich, Erich [Institute of Cancer Research, Department of Medicine I, Medical University of Vienna, Borschkegasse 8a, A-1090 Vienna (Austria)]. E-mail: erich.heidenreich@meduniwien.ac.at; Eisler, Herfried [Institute of Cancer Research, Department of Medicine I, Medical University of Vienna, Borschkegasse 8a, A-1090 Vienna (Austria); Steinboeck, Ferdinand [Institute of Cancer Research, Department of Medicine I, Medical University of Vienna, Borschkegasse 8a, A-1090 Vienna (Austria)

    2006-01-29

    Mutations arising in times of cell cycle arrest may provide a selective advantage for unicellular organisms adapting to environmental changes. For multicellular organisms, however, they may pose a serious threat, in that such mutations in somatic cells contribute to carcinogenesis and ageing. The budding yeast Saccharomyces cerevisiae presents a convenient model system for studying the incidence and the mechanisms of stationary-phase mutation in a eukaryotic organism. Having studied the emergence of frameshift mutants after several days of starvation-induced cell cycle arrest, we previously reported that all (potentially error-prone) translesion synthesis (TLS) enzymes identified in S. cerevisiae did not contribute to the basal level of spontaneous stationary-phase mutations. However, we observed that an increased frequency of stationary-phase frameshift mutations, brought about by a defective nucleotide excision repair (NER) pathway or by UV irradiation, was dependent on Rev3p, the catalytic subunit of the TLS polymerase zeta (Pol {zeta}). Employing the same two conditions, we now examined the effect of deletions of the genes coding for polymerase eta (Pol {eta}) (RAD30) and Rev1p (REV1). In a NER-deficient strain background, the increased incidence of stationary-phase mutations was only moderately influenced by a lack of Pol {eta} but completely reduced to wild type level by a knockout of the REV1 gene. UV-induced stationary-phase mutations were abundant in wild type and rad30{delta} strains, but substantially reduced in a rev1{delta} as well as a rev3{delta} strain. The similarity of the rev1{delta} and the rev3{delta} phenotype and an epistatic relationship evident from experiments with a double-deficient strain suggests a participation of Rev1p and Rev3p in the same mutagenic pathway. Based on these results, we propose that the response of cell cycle-arrested cells to an excess of exo- or endogenously induced DNA damage includes a novel replication

  8. Comment on Weakly dissipative dust-ion acoustic wave modulation (J. Plasma Phys. 82, 905820104, 2016)

    Science.gov (United States)

    Kourakis, I.; Elkamash, I. S.

    2016-10-01

    In a recent article (J. Plasma Phys., vol. 82, 2009, 905820104), weakly dissipative dust-ion acoustic wave modulation in dusty plasmas was considered. It is shown in this Comment that the analysis therein involved severe fallacies, and is in fact based on an erroneous plasma fluid model, which fails to satisfy an equilibrium condition, among other shortcomings. The subsequent analysis therefore is dubious and of limited scientific value.

  9. Revised Safety Instruction 41 (IS41 REV.)

    CERN Multimedia

    SC Secretariat

    2005-01-01

    Please note that the Revised Safety Instruction No. 41 (IS41 REV.), entitled 'The use of plastic and other non-metallic materials at CERN with respect to fire safety and radiation resistance' is available on the web at the following url: https://edms.cern.ch/document/335806/LAST_RELEASED Paper copies can also be obtained from the SC Unit Secretariat, e-mail: sc.secretariat@cern.ch SC Secretariat

  10. CSL Wave Function Collapse Model as a Mechanism for the Emergence of Cosmological Asymmetries in Inflation

    CERN Document Server

    Cañate, Pedro; Sudarsky, Daniel

    2012-01-01

    As previously discussed in (D. Sudarsky, Int.J.Mod.Phys.D20:509-552, (2011); [arXiv:0906.0315]), the inflationary account for the emergence of the seeds of cosmic structure falls short of actually explaining the generation of primordial anisotropies and inhomogeneities. This description starts from a symmetric background, and invokes symmetric dynamics, so it cannot explain asymmetries. To generate asymmetries, we present an application of the Continuous Spontaneous Localization (CSL) model of wave function collapse (P. Pearle, Phys. Rev. A 39, 2277, (1989); G. C. Ghirardi, P. Pearle and A. Rimini, Phys. Rev. A42, 78 (1990)) in the context of inflation. This modification of quantum dynamics introduces a stochastic non-unitary component to the evolution of the inflaton field perturbations. This leads to passage from a homogeneous and isotropic stage to another, where the quantum uncertainties in the initial state of inflation transmute into the primordial inhomogeneities and anisotropies. We examine requiremen...

  11. Reply to "Comment on `Simple improvements to classical bubble nucleation models'"

    Science.gov (United States)

    Tanaka, Kyoko K.; Tanaka, Hidekazu; Angélil, Raymond; Diemand, Jürg

    2016-08-01

    We reply to the Comment by Schmelzer and Baidakov [Phys. Rev. E 94, 026801 (2016)]., 10.1103/PhysRevE.94.026801 They suggest that a more modern approach than the classic description by Tolman is necessary to model the surface tension of curved interfaces. Therefore we now consider the higher-order Helfrich correction, rather than the simpler first-order Tolman correction. Using a recent parametrization of the Helfrich correction provided by Wilhelmsen et al. [J. Chem. Phys. 142, 064706 (2015)], 10.1063/1.4907588, we test this description against measurements from our simulations, and find an agreement stronger than what the pure Tolman description offers. Our analyses suggest a necessary correction of order higher than the second for small bubbles with radius ≲1 nm. In addition, we respond to other minor criticism about our results.

  12. Superconducting correlations and thermodynamic properties in 2D square and triangular t-J model

    Science.gov (United States)

    Ogata, Masao

    2006-03-01

    Equal-time superconducting correlation functions of the two-dimensional t-J model on the square lattice are studied using high-temperature expansion method.[1] The sum of the pairing correlation, its spatial dependence and correlation length are obtained down to T ˜0.2t. By comparison of single-particle contributions in the correlation functions, we find effective attractive interactions between quasi-particles in dx^2-y^2-wave channel. It is shown that d-wave correlation grows rapidly at low temperatures for the doping 0.1 0 with hole doping, a rapid growth of effective d-wave paring interaction is found that indicates the resonating-valence-bond superconductivity. In contrast, when tJ. Phys. Soc. Japan 74, 1390 (2005). [2] T. Koretsune and M. Ogata, Phys. Rev. Lett. 89, 116401 (2002), and Phys. Rev. B72, 134513 (2005).

  13. Reply to "Comment on 'Simple improvements to classical bubble nucleation models' ".

    Science.gov (United States)

    Tanaka, Kyoko K; Tanaka, Hidekazu; Angélil, Raymond; Diemand, Jürg

    2016-08-01

    We reply to the Comment by Schmelzer and Baidakov [Phys. Rev. E 94, 026801 (2016)].10.1103/PhysRevE.94.026801 They suggest that a more modern approach than the classic description by Tolman is necessary to model the surface tension of curved interfaces. Therefore we now consider the higher-order Helfrich correction, rather than the simpler first-order Tolman correction. Using a recent parametrization of the Helfrich correction provided by Wilhelmsen et al. [J. Chem. Phys. 142, 064706 (2015)]JCPSA60021-960610.1063/1.4907588, we test this description against measurements from our simulations, and find an agreement stronger than what the pure Tolman description offers. Our analyses suggest a necessary correction of order higher than the second for small bubbles with radius ≲1 nm. In addition, we respond to other minor criticism about our results.

  14. Anisotropic 2-dimensional Robin Hood model

    Science.gov (United States)

    Buldyrev, Sergey; Cwilich, Gabriel; Zypman, Fredy

    2009-03-01

    We have considered the Robin Hood model introduced by Zaitsev[1] to discuss flux creep and depinning of interfaces in a two dimensional system. Although the model has been studied extensively analytically in 1-d [2], its scaling laws have been verified numerically only in that case. Recent work suggest that its properties might be important to understand surface friction[3], where its 2-dimensional properties are important. We show that in the 2-dimensional case scaling laws can be found provided one considers carefully the anisotropy of the model, and different ways of introducing that anisotropy lead to different exponents and scaling laws, in analogy with directed percolation, with which this model is closely related[4]. We show that breaking the rotational symmetry between the x and y axes does not change the scaling properties of the model, but the introduction of a preferential direction of accretion (``robbing'' in the language of the model) leads to new scaling exponents. [1] S.I.Zaitsev, Physica A189, 411 (1992) [2] M. Pacuzki, S. Maslov and P.Bak, Phys Rev. E53, 414 (1996) [3] S. Buldyrev, J. Ferrante and F. Zypman Phys. Rev E64, 066110 (2006) [4] G. Odor, Rev. Mod. Phys. 76, 663 (2004) .

  15. The PhysTEC Teacher Education Program at FIU

    Science.gov (United States)

    Kramer, Laird

    2010-10-01

    The FIU PhysTEC Project is an integral component of the Physics Department's educational transformation that has led to more than a ten-fold increase in majors. The transformation seeks to increase the quality and quantity of physics majors and future physics teachers, including those from historically underrepresented groups. Elements of the efforts include transformed introductory physics courses, establishment of a physics research and learning community, engagement of stakeholders spanning high school through the university administration, and advocacy by a physics education research group. The PhysTEC Project supports future physics teachers through a Learning Assistant program coupled to newly revised secondary education programs. The Learning Assistant program is an experiential program that recruits new students into teaching careers while providing a mechanism for transforming courses - undergraduates experience the rewards and intellectual challenges of teaching through providing interactive engagement learning experiences for their peers in introductory physics courses. Students that continue in the program enroll in a multidisciplinary teacher preparation program and may receive significant financial support. FIU is a minority-serving urban public research institution in Miami, Florida serving over 39,000 students, of which 64% are Hispanic, 13% are Black, and 56% are women. Programmatic strategies and impacts of the program will be provided.

  16. An H Theorem for Boltzmann's Equation for the Yard-Sale Model of Asset Exchange

    Science.gov (United States)

    Boghosian, Bruce M.; Johnson, Merek; Marcq, Jeremy A.

    2015-12-01

    In recent work (Boghosian, Phys Rev E 89:042804-042825, 2014; Boghosian, Int J Mod Phys 25:1441008-1441015, 2014), Boltzmann and Fokker-Planck equations were derived for the "Yard-Sale Model" of asset exchange. For the version of the model without redistribution, it was conjectured, based on numerical evidence, that the time-asymptotic state of the model was oligarchy—complete concentration of wealth by a single individual. In this work, we prove that conjecture by demonstrating that the Gini coefficient, a measure of inequality commonly used by economists, is an H function of both the Boltzmann and Fokker-Planck equations for the model.

  17. Eighth-order phase-field-crystal model for two-dimensional crystallization

    OpenAIRE

    Jaatinen, A.; Ala-Nissila, T.

    2010-01-01

    We present a derivation of the recently proposed eighth order phase field crystal model [Jaatinen et al., Phys. Rev. E 80, 031602 (2009)] for the crystallization of a solid from an undercooled melt. The model is used to study the planar growth of a two dimensional hexagonal crystal, and the results are compared against similar results from dynamical density functional theory of Marconi and Tarazona, as well as other phase field crystal models. We find that among the phase field crystal models...

  18. Introducing RevPASH: The Free Webtool Application

    Directory of Open Access Journals (Sweden)

    Peter Szende

    2014-10-01

    Full Text Available RevPASH (Revenue Per Available Seat Hour is an important measure that helps restaurant operators understand how efficiently each seat in a restaurant generates revenue. The RevPASH app is an easy-to-use web-tool that provides an operator with a quick way to input a few relevant numbers and calculate RevPASH.The application has the ability to compare RevPASH over different times, days, weeks, and months.

  19. Predicting dislocation climb: Classical modeling versus atomistic simulations

    OpenAIRE

    Clouet, Emmanuel

    2011-01-01

    International audience; The classical modeling of dislocation climb based on a continuous description of vacancy diffusion is compared to recent atomistic simulations of dislocation climb in body-centered cubic iron under vacancy supersaturation [Phys. Rev. Lett. 105 095501 (2010)]. A quantitative agreement is obtained, showing the ability of the classical approach to describe dislocation climb. The analytical model is then used to extrapolate dislocation climb velocities to lower dislocation...

  20. Publisher's Note: Search for ultrahigh energy neutrinos in highly inclined events at the Pierre Auger Observatory [Phys. Rev. D 84, 122005

    NARCIS (Netherlands)

    Abreu, P.; Aglietta, M.; Ahlers, M.; Ahn, E. J.; Albuquerque, I. F. M.; Allard, D.; Allekotte, I.; Allen, J.; Allison, P.; Almela, A.; Alvarez Castillo, J.; Alvarez-Muñiz, J.; Ambrosio, M.; Aminaei, A.; Anchordoqui, L.; Andringa, S.; Anticic, T.; Aramo, C.; Arganda, E.; Arqueros, F.; Asorey, H.; Assis, P.; Aublin, J.; Ave, M.; Avenier, M.; Avila, G.; Bäcker, T.; Badescu, A. M.; Balzer, M.; Barber, K. B.; Barbosa, A. F.; Bardenet, R.; Barroso, S. L. C.; Baughman, B.; Bäuml, J.; Beatty, J. J.; Becker, B. R.; Becker, K. H.; Bellétoile, A.; Bellido, J. A.; Benzvi, S.; Berat, C.; Bertou, X.; Biermann, P. L.; Billoir, P.; Blanco, F.; Blanco, M.; Bleve, C.; Blümer, H.; Bohácová, M.; Boncioli, D.; Bonifazi, C.; Bonino, R.; Borodai, N.; Brack, J.; Brancus, I.; Brogueira, P.; Brown, W. C.; Bruijn, R.; Buchholz, P.; Bueno, A.; Burton, R. E.; Caballero-Mora, K. S.; Caccianiga, B.; Caramete, L.; Caruso, R.; Castellina, A.; Catalano, O.; Cataldi, G.; Cazon, L.; Cester, R.; Chauvin, J.; Cheng, S. H.; Chiavassa, A.; Chinellato, J. A.; Chirinos Diaz, J.; Chudoba, J.; Clay, R. W.; Coluccia, M. R.; Conceição, R.; Contreras, F.; Cook, H.; Cooper, M. J.; Coppens, J.; Cordier, A.; Coutu, S.; Covault, C. E.; Creusot, A.; Criss, A.; Cronin, J.; Curutiu, A.; Dagoret-Campagne, S.; Dallier, R.; Dasso, S.; Daumiller, K.; Dawson, B. R.; de Almeida, R. M.; de Domenico, M.; de Donato, C.; de Jong, S. J.; de La Vega, G.; de Mello, W. J. M., Jr.; de Mello Neto, J. R. T.; de Mitri, I.; de Souza, V.; de Vries, K. D.; Del Peral, L.; Del Río, M.; Deligny, O.; Dembinski, H.; Dhital, N.; di Giulio, C.; Díaz Castro, M. L.; Diep, P. N.; Diogo, F.; Dobrigkeit, C.; Docters, W.; D'Olivo, J. C.; Dong, P. N.; Dorofeev, A.; Dos Anjos, J. C.; Dova, M. T.; D'Urso, D.; Dutan, I.; Ebr, J.; Engel, R.; Erdmann, M.; Escobar, C. O.; Espadanal, J.; Etchegoyen, A.; Facal San Luis, P.; Fajardo Tapia, I.; Falcke, H.; Farrar, G.; Fauth, A. C.; Fazzini, N.; Ferguson, A. P.; Fick, B.; Filevich, A.; Filipcic, A.; Fliescher, S.; Fracchiolla, C. E.; Fraenkel, E. D.; Fratu, O.; Fröhlich, U.; Fuchs, B.; Gaior, R.; Gamarra, R. F.; Gambetta, S.; García, B.; Garcia Roca, S. T.; Garcia-Gamez, D.; Garcia-Pinto, D.; Gascon, A.; Gemmeke, H.; Ghia, P. L.; Giaccari, U.; Giller, M.; Glass, H.; Gold, M. S.; Golup, G.; Gomez Albarracin, F.; Gómez Berisso, M.; Gómez Vitale, P. F.; Gonçalves, P.; Gonzalez, D.; Gonzalez, J. G.; Gookin, B.; Gorgi, A.; Gouffon, P.; Grashorn, E.; Grebe, S.; Griffith, N.; Grigat, M.; Grillo, A. F.; Guardincerri, Y.; Guarino, F.; Guedes, G. P.; Guzman, A.; Hansen, P.; Harari, D.; Harmsma, S.; Harrison, T. A.; Harton, J. L.; Haungs, A.; Hebbeker, T.; Heck, D.; Herve, A. E.; Hojvat, C.; Hollon, N.; Holmes, V. C.; Homola, P.; Hörandel, J. R.; Horneffer, A.; Horvath, P.; Hrabovský, M.; Huber, D.; Huege, T.; Insolia, A.; Ionita, F.; Italiano, A.; Jarne, C.; Jiraskova, S.; Josebachuili, M.; Kadija, K.; Kampert, K. H.; Karhan, P.; Kasper, P.; Kégl, B.; Keilhauer, B.; Keivani, A.; Kelley, J. L.; Kemp, E.; Kieckhafer, R. M.; Klages, H. O.; Kleifges, M.; Kleinfeller, J.; Knapp, J.; Koang, D.-H.; Kotera, K.; Krohm, N.; Krömer, O.; Kruppke-Hansen, D.; Kuehn, F.; Kuempel, D.; Kulbartz, J. K.; Kunka, N.; La Rosa, G.; Lachaud, C.; Lauer, R.; Lautridou, P.; Le Coz, S.; Leão, M. S. A. B.; Lebrun, D.; Lebrun, P.; Leigui de Oliveira, M. A.; Letessier-Selvon, A.; Lhenry-Yvon, I.; Link, K.; López, R.; Lopez Agüera, A.; Louedec, K.; Lozano Bahilo, J.; Lu, L.; Lucero, A.; Ludwig, M.; Lyberis, H.; Macolino, C.; Maldera, S.; Mandat, D.; Mantsch, P.; Mariazzi, A. G.; Marin, J.; Marin, V.; Maris, I. C.; Marquez Falcon, H. R.; Marsella, G.; Martello, D.; Martin, L.; Martinez, H.; Martínez Bravo, O.; Mathes, H. J.; Matthews, J.; Matthews, J. A. J.; Matthiae, G.; Maurel, D.; Maurizio, D.; Mazur, P. O.; Medina-Tanco, G.; Melissas, M.; Melo, D.; Menichetti, E.; Menshikov, A.; Mertsch, P.; Meurer, C.; Micanovic, S.; Micheletti, M. I.; Miramonti, L.; Molina-Bueno, L.; Mollerach, S.; Monasor, M.; Monnier Ragaigne, D.; Montanet, F.; Morales, B.; Morello, C.; Moreno, E.; Moreno, J. C.; Mostafá, M.; Moura, C. A.; Muller, M. A.; Müller, G.; Münchmeyer, M.; Mussa, R.; Navarra, G.; Navarro, J. L.; Navas, S.; Necesal, P.; Nellen, L.; Nelles, A.; Neuser, J.; Newton, D.; Nhung, P. T.; Niechciol, M.; Niemietz, L.; Nierstenhoefer, N.; Nitz, D.; Nosek, D.; Nožka, L.; Nyklicek, M.; Oehlschläger, J.; Olinto, A.; Ortiz, M.; Pacheco, N.; Pakk Selmi-Dei, D.; Palatka, M.; Pallotta, J.; Palmieri, N.; Parente, G.; Parizot, E.; Parra, A.; Pastor, S.; Paul, T.; Pech, M.; Pekala, J.; Pelayo, R.; Pepe, I. M.; Perrone, L.; Pesce, R.; Petermann, E.; Petrera, S.; Petrinca, P.; Petrolini, A.; Petrov, Y.; Pfendner, C.; Piegaia, R.; Pierog, T.; Pieroni, P.; Pimenta, M.

    2012-01-01

    The Surface Detector of the Pierre Auger Observatory is sensitive to neutrinos of all flavours above 0.1 EeV. These interact through charged and neutral currents in the atmosphere giving rise to extensive air showers. When interacting deeply in the atmosphere at nearly horizontal incidence, neutrino

  1. Comment on Y. Couder and E. Fort: "Single-Particle Diffraction and Interference at a Macroscopic Scale", Phys. Rev. Lett. (2006)

    CERN Document Server

    Andersen, Anders; Reichelt, Christian; Ahl, Sonja Rosenlund; Lautrup, Benny; Ellegaard, Clive; Levinsen, Mogens T; Bohr, Tomas

    2014-01-01

    In a paper from 2006, Couder and Fort [1] describe a version of the famous double slit experiment performed with drops bouncing on a vibrated fluid surface, where interference in the particle statistics is found even though it is possible to determine unambiguously which slit the "walking" drop passes. It is one of the first papers in an impressive series, showing that such walking drops closely resemble de Broglie waves and can reproduce typical quantum phenomena like tunneling and quantized states [2-13]. The double slit experiment is, however, a more stringent test of quantum mechanics, because it relies upon superposition and phase coherence. In the present comment we first point out that the experimental data presented in [1] are not convincing, and secondly we argue that it is not possible in general to capture quantum mechanical results in a system, where the trajectory of the particle is well-defined.

  2. Comment on "Observation of a push force on the end face of a nanometer silica filament exerted by outgoing light," Phys. Rev. Lett. 101, 243601 (2008)

    CERN Document Server

    Mansuripur, Masud

    2012-01-01

    In a recent paper, W. She, J. Yu and R. Feng reported the slight deformations observed upon transmission of a light pulse through a fairly short length of a silica glass nano-fiber. Relating the shape and magnitude of these deformations to the momentum of the light pulse both inside and outside the fiber, these authors concluded that, within the fiber, the photons carry the Abraham momentum. In my view, the authors' claim that they have resolved the Abraham-Minkowski controversy surrounding the momentum of photons inside dielectric media is premature. A correct interpretation of the experiments of She et al requires precise calculations that would properly account not only for the electromagnetic momentum (both inside and outside the fiber) but also for the Lorentz force exerted on the fiber by the light pulse in its entire path through this nano-waveguide.

  3. Introduction to "contextual values" and a simpler counterexample to a claim of Dressel, Agarwal, and Jordan [Phys. Rev. Lett. 104 240401 (2010)

    CERN Document Server

    Parrott, Stephen

    2011-01-01

    The abstract of the paper mentioned in the title, called DAJ below, states: "We introduce contextual values as a generalization of the eigenvalues of an observable that takes into account both the system observable and a general measurement procedure. This technique leads to a natural definition of a general conditioned average that converges uniquely to the quantum weak value in the minimal disturbance limit." A counterexample to the claim of the last sentence was presented in arXiv:1102.4407v6, a 32-page paper discussing various topics related to DAJ. The counterexample relied on a fairly complicated solution of a system of linear equations with algebraic coefficients, and so was not entirely intuitive. The second half of the present note gives a simplified counterexample, all of whose steps can be verified mentally. The first half summarizes the main ideas of DAJ.

  4. Publisher's Note: Search for ultrahigh energy neutrinos in highly inclined events at the Pierre Auger Observatory [Phys. Rev. D 84, 122005 (2011)

    Science.gov (United States)

    Abreu, P.; Aglietta, M.; Ahlers, M.; Ahn, E. J.; Albuquerque, I. F. M.; Allard, D.; Allekotte, I.; Allen, J.; Allison, P.; Almela, A.; Alvarez Castillo, J.; Alvarez-Muñiz, J.; Ambrosio, M.; Aminaei, A.; Anchordoqui, L.; Andringa, S.; Anticic, T.; Aramo, C.; Arganda, E.; Arqueros, F.; Asorey, H.; Assis, P.; Aublin, J.; Ave, M.; Avenier, M.; Avila, G.; Bäcker, T.; Badescu, A. M.; Balzer, M.; Barber, K. B.; Barbosa, A. F.; Bardenet, R.; Barroso, S. L. C.; Baughman, B.; Bäuml, J.; Beatty, J. J.; Becker, B. R.; Becker, K. H.; Bellétoile, A.; Bellido, J. A.; Benzvi, S.; Berat, C.; Bertou, X.; Biermann, P. L.; Billoir, P.; Blanco, F.; Blanco, M.; Bleve, C.; Blümer, H.; Bohácová, M.; Boncioli, D.; Bonifazi, C.; Bonino, R.; Borodai, N.; Brack, J.; Brancus, I.; Brogueira, P.; Brown, W. C.; Bruijn, R.; Buchholz, P.; Bueno, A.; Burton, R. E.; Caballero-Mora, K. S.; Caccianiga, B.; Caramete, L.; Caruso, R.; Castellina, A.; Catalano, O.; Cataldi, G.; Cazon, L.; Cester, R.; Chauvin, J.; Cheng, S. H.; Chiavassa, A.; Chinellato, J. A.; Chirinos Diaz, J.; Chudoba, J.; Clay, R. W.; Coluccia, M. R.; Conceição, R.; Contreras, F.; Cook, H.; Cooper, M. J.; Coppens, J.; Cordier, A.; Coutu, S.; Covault, C. E.; Creusot, A.; Criss, A.; Cronin, J.; Curutiu, A.; Dagoret-Campagne, S.; Dallier, R.; Dasso, S.; Daumiller, K.; Dawson, B. R.; de Almeida, R. M.; de Domenico, M.; de Donato, C.; de Jong, S. J.; de La Vega, G.; de Mello, W. J. M., Jr.; de Mello Neto, J. R. T.; de Mitri, I.; de Souza, V.; de Vries, K. D.; Del Peral, L.; Del Río, M.; Deligny, O.; Dembinski, H.; Dhital, N.; di Giulio, C.; Díaz Castro, M. L.; Diep, P. N.; Diogo, F.; Dobrigkeit, C.; Docters, W.; D'Olivo, J. C.; Dong, P. N.; Dorofeev, A.; Dos Anjos, J. C.; Dova, M. T.; D'Urso, D.; Dutan, I.; Ebr, J.; Engel, R.; Erdmann, M.; Escobar, C. O.; Espadanal, J.; Etchegoyen, A.; Facal San Luis, P.; Fajardo Tapia, I.; Falcke, H.; Farrar, G.; Fauth, A. C.; Fazzini, N.; Ferguson, A. P.; Fick, B.; Filevich, A.; Filipcic, A.; Fliescher, S.; Fracchiolla, C. E.; Fraenkel, E. D.; Fratu, O.; Fröhlich, U.; Fuchs, B.; Gaior, R.; Gamarra, R. F.; Gambetta, S.; García, B.; Garcia Roca, S. T.; Garcia-Gamez, D.; Garcia-Pinto, D.; Gascon, A.; Gemmeke, H.; Ghia, P. L.; Giaccari, U.; Giller, M.; Glass, H.; Gold, M. S.; Golup, G.; Gomez Albarracin, F.; Gómez Berisso, M.; Gómez Vitale, P. F.; Gonçalves, P.; Gonzalez, D.; Gonzalez, J. G.; Gookin, B.; Gorgi, A.; Gouffon, P.; Grashorn, E.; Grebe, S.; Griffith, N.; Grigat, M.; Grillo, A. F.; Guardincerri, Y.; Guarino, F.; Guedes, G. P.; Guzman, A.; Hansen, P.; Harari, D.; Harmsma, S.; Harrison, T. A.; Harton, J. L.; Haungs, A.; Hebbeker, T.; Heck, D.; Herve, A. E.; Hojvat, C.; Hollon, N.; Holmes, V. C.; Homola, P.; Hörandel, J. R.; Horneffer, A.; Horvath, P.; Hrabovský, M.; Huber, D.; Huege, T.; Insolia, A.; Ionita, F.; Italiano, A.; Jarne, C.; Jiraskova, S.; Josebachuili, M.; Kadija, K.; Kampert, K. H.; Karhan, P.; Kasper, P.; Kégl, B.; Keilhauer, B.; Keivani, A.; Kelley, J. L.; Kemp, E.; Kieckhafer, R. M.; Klages, H. O.; Kleifges, M.; Kleinfeller, J.; Knapp, J.; Koang, D.-H.; Kotera, K.; Krohm, N.; Krömer, O.; Kruppke-Hansen, D.; Kuehn, F.; Kuempel, D.; Kulbartz, J. K.; Kunka, N.; La Rosa, G.; Lachaud, C.; Lauer, R.; Lautridou, P.; Le Coz, S.; Leão, M. S. A. B.; Lebrun, D.; Lebrun, P.; Leigui de Oliveira, M. A.; Letessier-Selvon, A.; Lhenry-Yvon, I.; Link, K.; López, R.; Lopez Agüera, A.; Louedec, K.; Lozano Bahilo, J.; Lu, L.; Lucero, A.; Ludwig, M.; Lyberis, H.; Macolino, C.; Maldera, S.; Mandat, D.; Mantsch, P.; Mariazzi, A. G.; Marin, J.; Marin, V.; Maris, I. C.; Marquez Falcon, H. R.; Marsella, G.; Martello, D.; Martin, L.; Martinez, H.; Martínez Bravo, O.; Mathes, H. J.; Matthews, J.; Matthews, J. A. J.; Matthiae, G.; Maurel, D.; Maurizio, D.; Mazur, P. O.; Medina-Tanco, G.; Melissas, M.; Melo, D.; Menichetti, E.; Menshikov, A.; Mertsch, P.; Meurer, C.; Micanovic, S.; Micheletti, M. I.; Miramonti, L.; Molina-Bueno, L.; Mollerach, S.; Monasor, M.; Monnier Ragaigne, D.; Montanet, F.; Morales, B.; Morello, C.; Moreno, E.; Moreno, J. C.; Mostafá, M.; Moura, C. A.; Muller, M. A.; Müller, G.; Münchmeyer, M.; Mussa, R.; Navarra, G.; Navarro, J. L.; Navas, S.; Necesal, P.; Nellen, L.; Nelles, A.; Neuser, J.; Newton, D.; Nhung, P. T.; Niechciol, M.; Niemietz, L.; Nierstenhoefer, N.; Nitz, D.; Nosek, D.; Nožka, L.; Nyklicek, M.; Oehlschläger, J.; Olinto, A.; Ortiz, M.; Pacheco, N.; Pakk Selmi-Dei, D.; Palatka, M.; Pallotta, J.; Palmieri, N.; Parente, G.; Parizot, E.; Parra, A.; Pastor, S.; Paul, T.; Pech, M.; Pekala, J.; Pelayo, R.; Pepe, I. M.; Perrone, L.; Pesce, R.; Petermann, E.; Petrera, S.; Petrinca, P.; Petrolini, A.; Petrov, Y.; Pfendner, C.; Piegaia, R.; Pierog, T.; Pieroni, P.; Pimenta, M.; Pirronello, V.; Platino, M.; Ponce, V. H.; Pontz, M.; Porcelli, A.; Privitera, P.; Prouza, M.; Quel, E. J.; Querchfeld, S.; Rautenberg, J.; Ravel, O.; Ravignani, D.; Revenu, B.; Ridky, J.; Riggi, S.; Risse, M.; Ristori, P.; Rivera, H.; Rizi, V.; Roberts, J.; Rodrigues de Carvalho, W.; Rodriguez, G.; Rodriguez Martino, J.; Rodriguez Rojo, J.; Rodriguez-Cabo, I.; Rodríguez-Frías, M. D.; Ros, G.; Rosado, J.; Rossler, T.; Roth, M.; Rouillé-D'Orfeuil, B.; Roulet, E.; Rovero, A. C.; Rühle, C.; Saftoiu, A.; Salamida, F.; Salazar, H.; Salesa Greus, F.; Salina, G.; Sánchez, F.; Santo, C. E.; Santos, E.; Santos, E. M.; Sarazin, F.; Sarkar, B.; Sarkar, S.; Sato, R.; Scharf, N.; Scherini, V.; Schieler, H.; Schiffer, P.; Schmidt, A.; Scholten, O.; Schoorlemmer, H.; Schovancova, J.; Schovánek, P.; Schröder, F.; Schulte, S.; Schuster, D.; Sciutto, S. J.; Scuderi, M.; Segreto, A.; Settimo, M.; Shadkam, A.; Shellard, R. C.; Sidelnik, I.; Sigl, G.; Silva Lopez, H. H.; Sima, O.; Smialkowski, A.; Šmída, R.; Snow, G. R.; Sommers, P.; Sorokin, J.; Spinka, H.; Squartini, R.; Srivastava, Y. N.; Stanic, S.; Stapleton, J.; Stasielak, J.; Stephan, M.; Stutz, A.; Suarez, F.; Suomijärvi, T.; Supanitsky, A. D.; Šuša, T.; Sutherland, M. S.; Swain, J.; Szadkowski, Z.; Szuba, M.; Tapia, A.; Tartare, M.; Tascau, O.; Tavera Ruiz, C. G.; Tcaciuc, R.; Tegolo, D.; Thao, N. T.; Thomas, D.; Tiffenberg, J.; Timmermans, C.; Tkaczyk, W.; Todero Peixoto, C. J.; Toma, G.; Tomé, B.; Tonachini, A.; Travnicek, P.; Tridapalli, D. B.; Tristram, G.; Trovato, E.; Tueros, M.; Ulrich, R.; Unger, M.; Urban, M.; Valdés Galicia, J. F.; Valiño, I.; Valore, L.; van den Berg, A. M.; Varela, E.; Vargas Cárdenas, B.; Vázquez, J. R.; Vázquez, R. A.; Veberic, D.; Verzi, V.; Vicha, J.; Videla, M.; Villaseñor, L.; Wahlberg, H.; Wahrlich, P.; Wainberg, O.; Walz, D.; Watson, A. A.; Weber, M.; Weidenhaupt, K.; Weindl, A.; Werner, F.; Westerhoff, S.; Whelan, B. J.; Widom, A.; Wieczorek, G.; Wiencke, L.; Wilczynska, B.; Wilczynski, H.; Will, M.; Williams, C.; Winchen, T.; Wommer, M.; Wundheiler, B.; Yamamoto, T.; Yapici, T.; Younk, P.; Yuan, G.; Yushkov, A.; Zamorano, B.; Zas, E.; Zavrtanik, D.; Zavrtanik, M.; Zaw, I.; Zepeda, A.; Zhu, Y.; Zimbres Silva, M.; Ziolkowski, M.

    2012-01-01

    The Surface Detector of the Pierre Auger Observatory is sensitive to neutrinos of all flavours above 0.1 EeV. These interact through charged and neutral currents in the atmosphere giving rise to extensive air showers. When interacting deeply in the atmosphere at nearly horizontal incidence, neutrinos can be distinguished from regular hadronic cosmic rays by the broad time structure of their shower signals in the water-Cherenkov detectors. In this paper we present for the first time an analysis based on down-going neutrinos. We describe the search procedure, the possible sources of background, the method to compute the exposure and the associated systematic uncertainties. No candidate neutrinos have been found in data collected from 1 January 2004 to 31 May 2010. Assuming an E^-2 differential energy spectrum the limit on the single flavour neutrino is (E^2 * dN/dE) < 1.74x10^-7 GeV cm^-2 s^-1 sr^-1 at 90% C.L. in the energy range 1x10^17 eV < E < 1x10^20 eV.

  5. Accelerating anisotropic cosmological model in f(R,T) theory of gravity

    Science.gov (United States)

    Santhi Kumar, R.; Satyannarayana, B.

    2017-10-01

    Field equations in a modified theory of gravitation proposed by Harko et al. (Phys Rev D 84:024020, 8) are obtained with the aid of a spatially homogeneous and anisotropic LRS Bianchi type-I metric. Cosmological models corresponding to false vacuum and dust universe are obtained. Some physical and kinematical properties of each of the models are discussed. These models may be physically significant for discussion at an early stage of evolution of the universe.

  6. Comments on ``The Euclidean gravitational action as black hole entropy, singularities, and space-time voids'' [J. Math. Phys. 49, 042501 (2008)

    Science.gov (United States)

    Mitra, Abhas

    2009-04-01

    We point out that the space-time void inferred by Castro [J. Math. Phys. 49, 042501 (2008)] results from his choice of a discontinuous radial gauge. Further since the integration constant α0=2M0 (G =c=1) occurring in the vacuum Hilbert/Schwarzschild solution of a neutral "point mass" is zero [Arnowitt et al., in Gravitation: An Introduction to Current Research, edited by L. Witten (Wiley, New York, 1962), Chap. 7, p. 227; also Phys. Rev. Lett. 4, 375 (1960). A. Mitra, Adv. Space Res. 38, 2917 (2006); Proceedings of the XIth Marcel-Grossmann Conference on General Relativity (World Scientific, Singapore, 2008), Vol. 3, p. 1968], Castro's gauge reduces to the well behaved and physical Hilbert gauge. Physically this means that true Hilbert/Schwarzschild black holes have unique gravitational mass M =0. Accordingly, the unphysical space-time void inferred by Castro is actually nonexistent.

  7. Switching studies for the Horns Rev 2 wind farm main cable

    DEFF Research Database (Denmark)

    Jensen, Christian Flytkjær; Faria da Silva, Filipe; Bak, Claus Leth

    2011-01-01

    This article proposes a method of constructing a PSCAD model suitable for switching studies in a system containing long HVAC cables. The transmission network connection to the 215 MW offshore wind farm Horns Rev 2 is used as a case study. The connection to Horns Rev 2 consists of two land cable...... model used in PSCAD are given. Results obtained using the model are compared to full scale measurement of the energization of the system, and good agreement is found. The influence of different simulation parameters are examined; amongst them the modeling of the screen, the relative permittivity...

  8. Exactly soluble model of boundary degeneracy

    Science.gov (United States)

    Ganeshan, Sriram; Gorshkov, Alexey V.; Gurarie, Victor; Galitski, Victor M.

    2017-01-01

    We investigate the topological degeneracy that can be realized in Abelian fractional quantum spin Hall states with multiply connected gapped boundaries. Such a topological degeneracy (also dubbed as "boundary degeneracy") does not require superconducting proximity effect and can be created by simply applying a depletion gate to the quantum spin Hall material and using a generic spin-mixing term (e.g., due to backscattering) to gap out the edge modes. We construct an exactly soluble microscopic model manifesting this topological degeneracy and solve it using the recently developed technique [S. Ganeshan and M. Levin, Phys. Rev. B 93, 075118 (2016), 10.1103/PhysRevB.93.075118]. The corresponding string operators spanning this degeneracy are explicitly calculated. It is argued that the proposed scheme is experimentally reasonable.

  9. The PhysTEC project: A perspective on what it takes to recruit and educate more physics teachers

    Science.gov (United States)

    Plisch, Monica

    2012-03-01

    The PhysTEC project has more than doubled the number of physics teachers educated at supported sites. These institutions were selected for their potential to implement change primarily in physics departments and build model teacher education programs. Key components of PhysTEC programs include active recruiting, early teaching experiences, pedagogical content knowledge, Learning Assistants, and induction and mentoring. Important structural elements include a program champion, a Teacher in Residence, assessment, collaboration, and institutional commitment. The PhysTEC project has supported about 20 institutions to date. In order to more fully address the national need for qualified physics teachers, the effort would need to be scaled up substantially. There is evidence of growing interest among physics departments in taking on this issue, and a national coalition committed to improving the education of future physics teachers has expanded to include more than 250 member institutions. The project is experimenting with targeted sites, funded at a lower level, to implement focused programs. In addition, PhysTEC is partnering with aligned efforts to magnify its impact. PhysTEC is a project led by APS with AAPT, and supported by the NSF and the APS Campaign for the 21st Century.

  10. Excited-state quantum phase transition in the Rabi model

    Science.gov (United States)

    Puebla, Ricardo; Hwang, Myung-Joong; Plenio, Martin B.

    2016-08-01

    The Rabi model, a two-level atom coupled to a harmonic oscillator, can undergo a second-order quantum phase transition (QPT) [M.-J. Hwang et al., Phys. Rev. Lett. 115, 180404 (2015), 10.1103/PhysRevLett.115.180404]. Here we show that the Rabi QPT accompanies critical behavior in the higher-energy excited states, i.e., the excited-state QPT (ESQPT). We derive analytic expressions for the semiclassical density of states, which show a logarithmic divergence at a critical energy eigenvalue in the broken symmetry (superradiant) phase. Moreover, we find that the logarithmic singularities in the density of states lead to singularities in the relevant observables in the system such as photon number and atomic polarization. We corroborate our analytical semiclassical prediction of the ESQPT in the Rabi model with its numerically exact quantum mechanical solution.

  11. Eighth-order phase-field-crystal model for two-dimensional crystallization

    Science.gov (United States)

    Jaatinen, A.; Ala-Nissila, T.

    2010-12-01

    We present a derivation of the recently proposed eighth-order phase-field crystal model [A. Jaatinen , Phys. Rev. E 80, 031602 (2009)10.1103/PhysRevE.80.031602] for the crystallization of a solid from an undercooled melt. The model is used to study the planar growth of a two-dimensional hexagonal crystal, and the results are compared against similar results from dynamical density functional theory of Marconi and Tarazona, as well as other phase-field crystal models. We find that among the phase-field crystal models studied, the eighth-order fitting scheme gives results in good agreement with the density functional theory for both static and dynamic properties, suggesting it is an accurate and computationally efficient approximation to the density functional theory.

  12. Charge-state-dependent energy loss of slow ions. II. Statistical atom model

    Science.gov (United States)

    Wilhelm, Richard A.; Möller, Wolfhard

    2016-05-01

    A model for charge-dependent energy loss of slow ions is developed based on the Thomas-Fermi statistical model of atoms. Using a modified electrostatic potential which takes the ionic charge into account, nuclear and electronic energy transfers are calculated, the latter by an extension of the Firsov model. To evaluate the importance of multiple collisions even in nanometer-thick target materials we use the charge-state-dependent potentials in a Monte Carlo simulation in the binary collision approximation and compare the results to experiment. The Monte Carlo results reproduce the incident charge-state dependence of measured data well [see R. A. Wilhelm et al., Phys. Rev. A 93, 052708 (2016), 10.1103/PhysRevA.93.052708], even though the experimentally observed charge exchange dependence is not included in the model.

  13. Extraction and interpretation of gammaN-->Delta form factors within a dynamical model

    Energy Technology Data Exchange (ETDEWEB)

    B. Juliá-Díaz, T.-S. H. Lee, T. Sato, and L. C. Smith

    2007-01-01

    Within the dynamical model of Refs. [Phys. Rev. C54, 2660 (1996); C63, 055201 (2001)], we perform an analysis of recent data of pion electroproduction reactions at energies near the {Delta}(1232) resonance. We discuss possible interpretations of the extracted bare and dressed {gamma} N {yields} {Delta} form factors in terms of relativistic constituent quark models and Lattice QCD calculations. Possible future developments are discussed.

  14. Ground-State Bands of Fm and No Isotopes in Cluster Model

    Institute of Scientific and Technical Information of China (English)

    XU Chang; REN Zhong-Zhou

    2006-01-01

    We investigate the ground-state rotational bands of nuclei with Z ≥ 100 using cluster model proposed by Buck et al. [Phys. Rev. Lett. 94 (2005) 202501]. The core-cluster decomposition of each nucleus is determined by the corresponding electric quadrupole transition strength B(E2 : 2+ → 0+). The theoretical spectra of fermium and nobelium isotopes are compared with available experimental data. Good agreement between model and data is obtained.

  15. Alicki's model of scattering-induced decoherence derived from Hamiltonian dynamics

    Energy Technology Data Exchange (ETDEWEB)

    Hellmich, Mario [Faculty of Physics, University of Bielefeld, 33615 Bielefeld (Germany)

    2004-09-10

    We study a semiphenomenological model introduced by Alicki (2002 Phys. Rev. A 65 034104), describing environmental decoherence by scattering of a Brownian particle in a gas environment. For a slightly wider class of models, we prove that the semigroup describing the dynamics of the Brownian particle can be approximated by the reduced dynamics arising from a Hamiltonian interaction between the particle and an infinite fermionic thermal gas reservoir, provided the scattering process is isotropic.

  16. The stability and gravitational Newtonian limit of a modified Randall-Sundrum model

    Energy Technology Data Exchange (ETDEWEB)

    Parvizi, Shahrokh; Shahbazi, Mojtaba [Tarbiat Modares University, Department of Physics, School of Sciences, P.O. Box 14155-4838, Tehran (Iran, Islamic Republic of)

    2016-01-15

    For a modified Randall-Sundrum model (Jones et al. in Phys. Rev. D 88:025048, 2013), the graviton equations are derived and the mass spectrum found. The latter includes a massless graviton and a continuum mass with a gap. There is no negative mass-squared in the spectrum, so the model is stable. The gravitational Newtonian limit is obtained with an exponentially suppressed modification from the extra dimension. (orig.)

  17. Comment on "Modeling of electrode polarization for electrolytic cells with a limited ionic adsorption".

    Science.gov (United States)

    Alexe-Ionescu, A L; Barbero, G; Lelidis, I

    2014-05-01

    Recently, Sawada [Phys. Rev. E 88, 032406 (2013)] proposed a model to take into account the dielectric dispersion of ionic origin in a weak electrolyte cell. We first show that the model is based on questionable assumptions. Next, we point out an error in the author's calculation of the current in the external circuit. Finally, we demonstrate why some criticism on recent papers is irrelevant.

  18. Aging and percolation dynamics in a Non-Poissonian temporal network model.

    Science.gov (United States)

    Moinet, Antoine; Starnini, Michele; Pastor-Satorras, Romualdo

    2016-08-01

    We present an exhaustive mathematical analysis of the recently proposed Non-Poissonian Activity Driven (NoPAD) model [Moinet et al., Phys. Rev. Lett. 114, 108701 (2015)PRLTAO0031-900710.1103/PhysRevLett.114.108701], a temporal network model incorporating the empirically observed bursty nature of social interactions. We focus on the aging effects emerging from the non-Poissonian dynamics of link activation, and on their effects on the topological properties of time-integrated networks, such as the degree distribution. Analytic expressions for the degree distribution of integrated networks as a function of time are derived, exploring both limits of vanishing and strong aging. We also address the percolation process occurring on these temporal networks, by computing the threshold for the emergence of a giant connected component, highlighting the aging dependence. Our analytic predictions are checked by means of extensive numerical simulations of the NoPAD model.

  19. Aging and percolation dynamics in a Non-Poissonian temporal network model

    Science.gov (United States)

    Moinet, Antoine; Starnini, Michele; Pastor-Satorras, Romualdo

    2016-08-01

    We present an exhaustive mathematical analysis of the recently proposed Non-Poissonian Activity Driven (NoPAD) model [Moinet et al., Phys. Rev. Lett. 114, 108701 (2015), 10.1103/PhysRevLett.114.108701], a temporal network model incorporating the empirically observed bursty nature of social interactions. We focus on the aging effects emerging from the non-Poissonian dynamics of link activation, and on their effects on the topological properties of time-integrated networks, such as the degree distribution. Analytic expressions for the degree distribution of integrated networks as a function of time are derived, exploring both limits of vanishing and strong aging. We also address the percolation process occurring on these temporal networks, by computing the threshold for the emergence of a giant connected component, highlighting the aging dependence. Our analytic predictions are checked by means of extensive numerical simulations of the NoPAD model.

  20. Plaquette order in the SU(6) Heisenberg model on the honeycomb lattice

    Science.gov (United States)

    Nataf, Pierre; Lajkó, Miklós; Corboz, Philippe; Läuchli, Andreas M.; Penc, Karlo; Mila, Frédéric

    2016-05-01

    We revisit the SU(6) Heisenberg model on the honeycomb lattice, which has been predicted to be a chiral spin liquid by mean-field theory [G. Szirmai et al., Phys. Rev. A 84, 011611(R) (2011), 10.1103/PhysRevA.84.011611]. Using exact diagonalizations of finite clusters, infinite projected entangled pair state simulations, and variational Monte Carlo simulations based on Gutzwiller projected wave functions, we provide strong evidence that the model with one particle per site and nearest-neighbor exchange actually develops plaquette order. This is further confirmed by the investigation of the model with a ring-exchange term, which shows that there is a transition between the plaquette state and the chiral state at a finite value of the ring-exchange term.

  1. Multi-dimensional Vlasov simulations and modeling of trapped-electron-driven filamentation of electron plasma waves

    Energy Technology Data Exchange (ETDEWEB)

    Berger, R. L., E-mail: berger5@llnl.gov; Cohen, B. I. [Lawrence Livermore National Laboratory, University of California, P.O. Box 808, Livermore, California 94551 (United States); Brunner, S., E-mail: stephan.brunner@epfl.ch [Centre de Recherches en Physique des Plasmas, Association Euratom-Confédération Suisse, Ecole Polytechnique Fédérale de Lausanne, CRPP-PPB, CH-1015 Lausanne (Switzerland); Banks, J. W. [Department of Mathematical Sciences, Rensselaer Polytechnic Institute, AE 301, 110 8th Street, Troy, New York 12180 (United States); Winjum, B. J. [Department of Electrical Engineering, University of California, Los Angeles, California 90095 (United States)

    2015-05-15

    Kinetic simulations of two-dimensional finite-amplitude electron plasma waves are performed in a one-wavelength long system. A systematic study of the most unstable linear sideband mode, in particular its growth rate γ and wavenumber k{sub y}, is carried out by scanning the amplitude and wavenumber of the initial wave. Simulation results are compared with numerical and analytical solutions to a two-dimensional nonlinear Schrödinger model [H. A. Rose and L. Yin, Phys. Plasmas 15, 042311 (2008)] and to the reduced model by Kruer et al. [Phys. Rev. Lett. 23, 838 (1969)] generalized to two dimensions.

  2. Administrative Circular No. 14 (Rev. 2)

    CERN Multimedia

    HR Department

    2007-01-01

    The HR Department wishes to draw the attention of members of the personnel to a number of amendments to Administrative Circular No. 14 (Rev. 2) entitled "Protection of members of the personnel against the financial consequences of illness, accident and disability" which came into force on 1st July 2006 (cf. Weekly Bulletin of 14 and 21 August 2006). Occupational Accident Declaration Form (HS50) https://cern.ch/service-procedures/AdminMan/Forms/HS50E.doc •\tIt must be completed within 10 working days of the date on which the accident occurred (§ 29.2.1), unless the person concerned is materially unable to meet this deadline. • The completed formula must be accompanied by a medical certificate giving details of any bodily injuries resulting from the accident (Annex 1, § 5). The medical certificate must be obtained from the doctor who has been consulted for that purpose. Benefits resulting from illnesses and accidents Medical treatment will cease to be reimbursed under ...

  3. The measurement problem resolved and local realism preserved via a collapse-free photon detection model

    Science.gov (United States)

    Gilbert, Barry C.; Sulcs, Sue

    1996-11-01

    A new realislic local model of light propagation and detection is described. The authors propose a novel stochastic model of low-intensity photon detection in which background noise is added to a part of the photon prior to absorption. In this model, in agreement with Planck, there is no quantization of the propagating field. The model has some similarities to theories advanced by E. Santos and T. Marshall in the last decade, but also has substantial deviations from these. A mechanism, conserving energy and momentum, is proposed by which a sudden collapse of the wave-packet is avoided. The experimental Bell inequality violation of Aspect. Grangier and Roger [Phys. Rev. Lett. 47, 460 (1981)] is discussed. The authors have carried out a computer simulation of a radio frequency (RF) analogue of the Einstein-Podolsky-Rosen thought experiment to illustrate how the manipulation of certain factors, especially signal to noise ratio, detector threshold and characteristics of the noise, enables the same Bell inequality to be either satisfied or violated by a realistic local model. Building on arguments by Santos. [Phys. Rev. A 46. 3646 (1992)], the appropriateness of this Bell lest is discussed. Neither the authors' stochastic-optical model, nor their RF analogue, involves an enhancement assumption of the type defined by Clauser and Horne [Phys. Rev. D 10, 526 (1974)].

  4. Ensemble-based Probabilistic Forecasting at Horns Rev

    DEFF Research Database (Denmark)

    Pinson, Pierre; Madsen, Henrik

    2009-01-01

    of probabilistic forecasts, the resolution of which may be maximized by using meteorological ensemble predictions as input. The paper concentrates on the test case of the Horns Rev wind form over a period of approximately 1 year, in order to describe, apply and discuss a complete ensemble-based probabilistic...... the benefit of yielding predictive distributions that are of increased reliability (in a probabilistic sense) in comparison with the raw ensemble forecasts, at the some time taking advantage of their high resolution. Copyright (C) 2008 John Wiley & Sons, Ltd....... are then converted into predictive distributions with an original adaptive kernel dressing method. The shape of the kernels is driven by a mean-variance model, the parameters of which ore recursively estimated in order to maximize the overall skill of obtained predictive distributions. Such a methodology has...

  5. Tunneling with a hydrodynamic pilot-wave model

    Science.gov (United States)

    Nachbin, André; Milewski, Paul A.; Bush, John W. M.

    2017-03-01

    Eddi et al. [Phys. Rev Lett. 102, 240401 (2009), 10.1103/PhysRevLett.102.240401] presented experimental results demonstrating the unpredictable tunneling of a classical wave-particle association as may arise when a droplet walking across the surface of a vibrating fluid bath approaches a submerged barrier. We here present a theoretical model that captures the influence of bottom topography on this wave-particle association and so enables us to investigate its interaction with barriers. The coupled wave-droplet dynamics results in unpredictable tunneling events. As reported in the experiments by Eddi et al. and as is the case in quantum tunneling [Gamow, Nature (London) 122, 805 (1928), 10.1038/122805b0], the predicted tunneling probability decreases exponentially with increasing barrier width. In the parameter regimes examined, tunneling between two cavities suggests an underlying stationary ergodic process for the droplet's position.

  6. Fractionalized Fermi liquid in a Kondo-Heisenberg model

    Science.gov (United States)

    Tsvelik, A. M.

    2016-10-01

    The Kondo-Heisenberg model is used as a controllable tool to demonstrate the existence of a peculiar metallic state with unbroken translational symmetry where the Fermi surface volume is not controlled by the total electron density. I use a nonperturbative approach where the strongest interactions are taken into account by means of exact solution, and corrections are controllable. In agreement with the general requirements formulated by T. Senthil et al. [Phys. Rev. Lett. 90, 216403 (2003), 10.1103/PhysRevLett.90.216403], the resulting metallic state represents a fractionalized Fermi liquid where well defined quasiparticles coexist with gapped fractionalized collective excitations. The system undergoes a phase transition to an ordered phase (charge density wave or superconducting), at the transition temperature which is parametrically small in comparison to the quasiparticle Fermi energy.

  7. Thermodynamic model of coherent island formation on vicinal substrate

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Xu, E-mail: zhangxubetter@gmail.com; Sun, Xiao-Hong [Henan Key Laboratory of Laser and Opto-electric Information Technology, School of Information Engineering, Zhengzhou University, Zhengzhou 450052 (China); Yu, Yanguang [School of Electrical, Computer and Telecommunications Engineering, University of Wollongong, Northfields Ave, Wollongong, New South Wales 2522 (Australia); Ren, Xiaomin [State Key Laboratory of Information Photonics and Optical Communications, Beijing University of Posts and Telecommunications, Beijing 100876 (China)

    2014-04-28

    A thermodynamic model has been proposed to address the formation of coherent island on the vicinal substrate. The morphological transition from square based island to elongated based one with various substrate misorientations is described. The initial stage of nucleation and growth process of islands in Stranski–Krastanow system is studied by taking into account the elastic deformations and the change of energy in the case of two-dimensional growth mode. The theoretical analysis shows the minimum nucleation barrier of island is on the decrease with increment of substrate misorientation, which means the nucleation of island on vicinal substrate is more favorable than that on flat substrate. By using the fitting data of experimental results done by Persichetti et al., [Phys. Rev. Lett. 104, 036104 (2010) and Phys. Rev. B 82, 121309(R) (2010)], we provide a meaningful explanation of the experimental observations.

  8. Thermodynamics of the one-dimensional parallel Kawasaki model: Exact solution and mean-field approximations

    Science.gov (United States)

    Pazzona, Federico G.; Demontis, Pierfranco; Suffritti, Giuseppe B.

    2014-08-01

    The adsorption isotherm for the recently proposed parallel Kawasaki (PK) lattice-gas model [Phys. Rev. E 88, 062144 (2013), 10.1103/PhysRevE.88.062144] is calculated exactly in one dimension. To do so, a third-order difference equation for the grand-canonical partition function is derived and solved analytically. In the present version of the PK model, the attraction and repulsion effects between two neighboring particles and between a particle and a neighboring empty site are ruled, respectively, by the dimensionless parameters ϕ and θ. We discuss the inflections induced in the isotherms by situations of high repulsion, the role played by finite lattice sizes in the emergence of substeps, and the adequacy of the two most widely used mean-field approximations in lattice gases, namely, the Bragg-Williams and the Bethe-Peierls approximations.

  9. Compass impurity model of Tb substitution in Sr2IrO4

    Science.gov (United States)

    Zhang, Long; Wang, Fa; Lee, Dung-Hai

    2016-10-01

    We show that upon Tb substitution the interaction between the magnetic moments on the impurity Tb4 + ion and its surrounding Ir4 + ions is described by a "compass" model, i.e., an Ising-like interaction favoring the magnetic moments across each bond to align along the bond direction. Such an interaction nucleates quenched magnetic vortices near the impurities and drives a reentrant transition out of the antiferromagnetic ordered phase at low temperatures, hence quickly suppressing the Néel temperature, consistent with the experiment [J. C. Wang et al., Phys. Rev. B 92, 214411 (2015), 10.1103/PhysRevB.92.214411]. As a by-product, we propose that the compass model can be realized in ordered double perovskites composed of spin-orbital-coupled d5 ions and half-closed-shell f7 ions.

  10. Kinetic simulations and reduced modeling of longitudinal sideband instabilities in non-linear electron plasma waves

    Energy Technology Data Exchange (ETDEWEB)

    Brunner, S. [Centre de Recherches en Physique des Plasmas, Association Euratom-Confédération Suisse, Ecole Polytechnique Fédérale de Lausanne, Lausanne, (Switzerland); Berger, R. L. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Cohen, B. I. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Hausammann, L. [Centre de Recherches en Physique des Plasmas, Association Euratom-Confédération Suisse, Ecole Polytechnique Fédérale de Lausanne, Lausanne, (Switzerland); Valeo, E. J. [Princeton Plasma Physics Lab. (PPPL), Princeton, NJ (United States)

    2014-10-01

    Kinetic Vlasov simulations of one-dimensional finite amplitude Electron Plasma Waves are performed in a multi-wavelength long system. A systematic study of the most unstable linear sideband mode, in particular its growth rate γ and quasi- wavenumber δk, is carried out by scanning the amplitude and wavenumber of the initial wave. Simulation results are successfully compared against numerical and analytical solutions to the reduced model by Kruer et al. [Phys. Rev. Lett. 23, 838 (1969)] for the Trapped Particle Instability (TPI). A model recently suggested by Dodin et al. [Phys. Rev. Lett. 110, 215006 (2013)], which in addition to the TPI accounts for the so-called Negative Mass Instability because of a more detailed representation of the trapped particle dynamics, is also studied and compared with simulations.

  11. Improved Analysis of GW150914 Using a Fully Spin-Precessing Waveform Model

    Directory of Open Access Journals (Sweden)

    2016-10-01

    Full Text Available This paper presents updated estimates of source parameters for GW150914, a binary black-hole coalescence event detected by the Laser Interferometer Gravitational-wave Observatory (LIGO in 2015 [Abbott et al. Phys. Rev. Lett. 116, 061102 (2016.]. Abbott et al. [Phys. Rev. Lett. 116, 241102 (2016.] presented parameter estimation of the source using a 13-dimensional, phenomenological precessing-spin model (precessing IMRPhenom and an 11-dimensional nonprecessing effective-one-body (EOB model calibrated to numerical-relativity simulations, which forces spin alignment (nonprecessing EOBNR. Here, we present new results that include a 15-dimensional precessing-spin waveform model (precessing EOBNR developed within the EOB formalism. We find good agreement with the parameters estimated previously [Abbott et al. Phys. Rev. Lett. 116, 241102 (2016.], and we quote updated component masses of 35_{-3}^{+5} M_{⊙} and 30_{-4}^{+3} M_{⊙} (where errors correspond to 90% symmetric credible intervals. We also present slightly tighter constraints on the dimensionless spin magnitudes of the two black holes, with a primary spin estimate <0.65 and a secondary spin estimate <0.75 at 90% probability. Abbott et al. [Phys. Rev. Lett. 116, 241102 (2016.] estimated the systematic parameter-extraction errors due to waveform-model uncertainty by combining the posterior probability densities of precessing IMRPhenom and nonprecessing EOBNR. Here, we find that the two precessing-spin models are in closer agreement, suggesting that these systematic errors are smaller than previously quoted.

  12. Preface: phys. stat. sol. (a) 202/12

    Science.gov (United States)

    Neumann, Wolfgang; Stutzmann, Martin; Hildebrandt, Stefan

    2005-09-01

    The present special issue contains a collection of Original Papers dedicated to Professor Johannes Heydenreich on the occasion of his 75th birthday.Johannes Heydenreich, born on 20 June 1930 in Plauen/Vogtland near Dresden, studied physics at the Pädagogische Hochschule Potsdam, where he obtained his first academic degree Dipl. Phys. in 1958. He received his doctoral degree at the Martin Luther University in Halle in 1961 and the Habilitation degree in 1969. Already during his studies in Potsdam, he showed an interest in electron microscopy due to the influence of his teacher and supervisor Prof. Picht, one of the pioneers in electron optics. His interests were strengthened when Johannes Heydenreich did the experimental work for his Diploma degree at the Institute for Experimental Physics of the University of Halle, where he met Prof. Heinz Bethge for the first time. This was the beginning of a fruitful and longstanding collaboration. In 1962 Johannes Heydenreich joined the team of the later Institute for Solid State Physics and Electron Microscopy of the Academy of Sciences of the GDR, in Halle, for which the basis was laid by Prof. Bethge in 1960.Heydenreich has been working as Assistant Director for many years and played a decisive role in introducing and organising the various techniques of electron microscopy in the institute.The research activities of Prof. Heydenreich covered a broad spectrum over the years. At the beginning of his career he made significant contributions in the field of electron mirror microscopy. After that, his main interests were focused on transmission electron microscopy, ranging from diffraction contrast analysis of crystal defects to high-resolution electron microscopy and image processing. His favourite field was studies of defect-induced phenomena in advanced materials. The so-called Bethge-Heydenreich, the book Electron Microscopy in Solid State Physics, published at first in a German edition in 1982 and later in a revised

  13. Reply to "Comment on 'Modeling of electrode polarization for electrolytic cells with a limited ionic adsorption' ".

    Science.gov (United States)

    Sawada, Atsushi

    2014-05-01

    The dielectric properties of dilute electrolytic solution cells have been measured in a low-frequency region, and the dielectric spectra have been analyzed in terms of space-charge polarization by using the Nernst-Planck (NP) model in the presence of ionic adsorption on electrodes [Phys. Rev. E 88, 032406 (2013)]. In the NP model, the internal electric field of the cell is considered to be approximately equal to the external field. In a Comment by Alexe-Ionescu et al. [Phys. Rev. E 89, 056401 (2014).] on our paper [Phys. Rev. E 88, 032406 (2013)], they claim the invalidity of the NP model and the necessity of the conventional Poisson-Nernst-Planck (PNP) model for the data analysis. Their criticisms are, however, originated from a viewpoint for determining the internal electric field, that is different from our approach. In this Reply, we show the validity of the NP model referring to our previous paper in which the conventional PNP model has been modified so as to correctly describe the actual internal field.

  14. Rev-erbα and Rev-erbβ coordinately protect the circadian clock and normal metabolic function

    DEFF Research Database (Denmark)

    Bugge, Anne Skovsø; Feng, Dan; Everett, Logan J;

    2012-01-01

    of binding sites across the genome, enriched near metabolic genes. Depletion of both Rev-erbs in liver synergistically derepresses several metabolic genes as well as genes that control the positive limb of the molecular clock. Moreover, deficiency of both Rev-erbs causes marked hepatic steatosis, in contrast...

  15. Orientation-field models for polycrystalline solidification: Grain coarsening and complex growth forms

    Science.gov (United States)

    Korbuly, Bálint; Pusztai, Tamás; Tóth, Gyula I.; Henry, Hervé; Plapp, Mathis; Gránásy, László

    2017-01-01

    We compare two versions of the phase-field theory for polycrystalline solidification, both relying on the concept of orientation fields: one by Kobayashi et al. [Physica D 140 (2000) 141] [15] and the other by Henry et al. [Phys. Rev. B 86 (2012) 054117] [22]. Setting the model parameters so that the grain boundary energies and the time scale of grain growth are comparable in the two models, we first study the grain coarsening process including the limiting grain size distribution, and compare the results to those from experiments on thin films, to the models of Hillert, and Mullins, and to predictions by multiphase-field theories. Next, following earlier work by Gránásy et al. [Phys. Rev. Lett. 88 (2002) 206105; Phys. Rev. E 72 (2005) 011605] [17,21], we extend the orientation field to the liquid state, where the orientation field is made to fluctuate in time and space, and employ the model for describing of multi-dendritic solidification, and polycrystalline growth, including the formation of "dizzy" dendrites disordered via the interaction with foreign particles.

  16. Electrophoresis of charged polymers: Simulation and scaling in a lattice model of reptation

    Science.gov (United States)

    Barkema, G. T.; Marko, J. F.; Widom, B.

    1994-06-01

    We report numerical results on the repton model of Rubinstein [Phys. Rev. Lett. 59, 1946 (1987)] as adapted by Duke [Phys. Rev. Lett. 62, 2877 (1989)] as a model for the gel electrophoresis of DNA. We describe an efficient algorithm with which we have simulated chains of N reptons with N several hundred in some instances. The diffusion coefficient D in the absence of an external electric field is obtained for NLeeuwen and Kooiman [Physica A 184, 79 (1992)]. The drift velocity v in a static field of variable strength E is obtained for various N and NE up to N=30 when NE is as small as 0.01 and up to N=400 when NE is as large as 20. We find that v has a finite, nonzero limit as N-->∞ at fixed E and that this limit is proportional to ||E||E, in accord with the conclusions of Duke, Semenov, and Viovy [Phys. Rev. Lett. 69, 3260 (1992)] for a different but related model. In a scaling limit in which N-->∞ and E-->0 the drift velocity in the repton model is fitted well by the formula N2v=NE[(1/3)2+(2NE/5)2]1/2 for all values of the scaling variable NE. We present a scaling analysis complementary to that of Duke, Semenov, and Viovy with which we rationalize the ||E||E behavior of the limiting drift velocity.

  17. Distribution of the largest event in the critical epidemic-type aftershock-sequence model.

    Science.gov (United States)

    Vere-Jones, David; Zhuang, Jiancang

    2008-10-01

    This Brief Report corrects and extends the results of Zhuang and Ogata [Phys. Rev. E 73, 046134 (2006)] on the asymptotic behavior of the largest event in the epidemic-type aftershock-sequence model for earthquake occurrence. We show that, in the special case that the underlying branching process is critical, there exists a previously unnoticed mode of behavior, which occurs when the expected family size grows relatively slowly.

  18. Five dimensional minimally interacting holographic dark energy model in Brans-Dicke theory of gravitation

    Science.gov (United States)

    Reddy, D. R. K.; Anitha, S.; Umadevi, S.

    2016-11-01

    In this paper, we investigate five dimensional space-time filled with minimally interacting dark matter and holographic dark energy in Brans-Dicke (Phys. Rev. 124:925, 1961) scalar-tensor theory of gravitation. The exact solutions of the field equations are obtained using (i) special law of variation for Hubble's parameter that yields constant value of deceleration parameter and (ii) a relation between metric potentials. The physical and geometrical aspects of the model are also discussed.

  19. SCAN-based hybrid and double-hybrid density functionals from models without fitted parameters

    OpenAIRE

    Hui, Kerwin; Chai, Jeng-Da

    2015-01-01

    By incorporating the nonempirical SCAN semilocal density functional [Sun, Ruzsinszky, and Perdew, Phys. Rev. Lett. 115, 036402 (2015)] in the underlying expression of four existing hybrid and double-hybrid models, we propose one hybrid (SCAN0) and three double-hybrid (SCAN0-DH, SCAN-QIDH, and SCAN0-2) density functionals, which are free from any fitted parameters. The SCAN-based double-hybrid functionals consistently outperform their parent SCAN semilocal functional for self-interaction probl...

  20. Simulation evidence for nonlocal interface models: two correlation lengths describe complete wetting.

    Science.gov (United States)

    Pang, Lijun; Landau, D P; Binder, K

    2011-06-10

    Monte Carlo simulations of (fluctuating) interfaces in Ising models confined between competing walls at temperatures above the wetting transition are presented and various correlation functions probing the interfacial fluctuation are computed. Evidence for the nonlocal interface Hamiltonian approach of A. O. Parry et al. [Phys. Rev. Lett. 93, 086104 (2004)] is given. In particular, we show that two correlation lengths exist with different dependence on the distance D between the walls.

  1. Conservation of the Dirac Current in Models with a General Spin Connection

    CERN Document Server

    Formiga, J B

    2012-01-01

    Here I obtain the conditions necessary for the conservation of the Dirac current when one substitutes the assumption $\\gamma^A_{\\ \\ |B}=0$ for $\\gamma^A_{\\ \\ |B}=[V_B,\\gamma^A]$, where the $\\gamma^A$s are the Dirac matrices and "$|$" represents the components of the covariant derivative. As an application, I apply these conditions to the model used in Ref. [M. Novello, Phys. Rev. {\\bf D8}, 2398 (1973)].

  2. Distribution of the largest event in the critical epidemic-type aftershock-sequence model

    Science.gov (United States)

    Vere-Jones, David; Zhuang, Jiancang

    2008-10-01

    This Brief Report corrects and extends the results of Zhuang and Ogata [Phys. Rev. E 73, 046134 (2006)] on the asymptotic behavior of the largest event in the epidemic-type aftershock-sequence model for earthquake occurrence. We show that, in the special case that the underlying branching process is critical, there exists a previously unnoticed mode of behavior, which occurs when the expected family size grows relatively slowly.

  3. Wave power plant at Horns Rev. Screening[Denmark]; Boelgekraftanlaeg ved Horns Rev. Screening

    Energy Technology Data Exchange (ETDEWEB)

    Soerensen, Hans C.; Nielsen, Kim; Steenstrup, P.R.; Friis-Madsen, E.; Wigant, L.

    2005-12-15

    The objective for the analysis has been to establish data for the sea at Horns Rev wind farm in the North Sea in order to assess the opportunity for using the site as test site for demonstration of wave energy devices exemplified by three different devices under development in Denmark. For comparison alternative sites like Hanstholm, Samsoe and Nissum Bredning are also assessed as well as the test centre EMEC at the Orkney Islands and the proposed test site Wave Hub at the north coast of Cornwall. The analysis shows that it is possible without major technical problems to connect 2-4 MW power generated by 3 different wave energy devices (AquaBuOY, Wave Star Energy and Wave Dragon) to the wind farm at Horns Rev (www.hornsrev.dk). The expenses for connection and regulation within the wind farm is about 200,000 DKK (30,00 EURO). On top of this comes the cost for individual sub sea cable connection to the wave devices, pull in of the sub sea cable through the existing J-tube in turbine T04 and the necessary regulation/control system in the individual wave devices to avoid damaging the power system in case of too high production. The analysis of the co-production of wind and wave power is dealt with in a separate report which shows that over a time period of half to one hour the time variation for wind generated electricity is 3 times as large as for wave energy generated power based on the actual measurement at Horns Rev. Further on the analysis shows that the wave generated power is more predictable than wind energy generated power as the power from the waves first is present about 2 hours after the wind is acting and last for 3 to 6 hours after the wind dies out; 6 to 12 hours with wind from west. The time is off course strongly depending of the direction of the wind i.e. the fetch. As this special report has a more general scope than the analysis as such it is reported in English (Annex Report II). The analysis shows that it is up to the individual device developer

  4. DNA nuclease activity of Rev-coupled transition metal chelates.

    Science.gov (United States)

    Joyner, Jeff C; Keuper, Kevin D; Cowan, J A

    2012-06-07

    Artificial nucleases containing Rev-coupled metal chelates based on combinations of the transition metals Fe(2+), Co(2+), Ni(2+), and Cu(2+) and the chelators DOTA, DTPA, EDTA, NTA, tripeptide GGH, and tetrapeptide KGHK have been tested for DNA nuclease activity. Originally designed to target reactive transition metal chelates (M-chelates) to the HIV-1 Rev response element mRNA, attachment to the arginine-rich Rev peptide also increases DNA-binding affinity for the attached M-chelates. Apparent K(D) values ranging from 1.7 to 3.6 µM base pairs for binding of supercoiled pUC19 plasmid DNA by Ni-chelate-Rev complexes were observed, as a result of electrostatic attraction between the positively-charged Rev peptide and negatively-charged DNA. Attachment of M-chelates to the Rev peptide resulted in enhancements of DNA nuclease activity ranging from 1-fold (no enhancement) to at least 13-fold (for Cu-DTPA-Rev), for the rate of DNA nicking, with second order rate constants for conversion of DNA(supercoiled) to DNA(nicked) up to 6 × 10(6) M(-1) min(-1), and for conversion of DNA(nicked) to DNA(linear) up to 1 × 10(5) M(-1) min(-1). Freifelder-Trumbo analysis and the ratios of linearization and nicking rate constants (k(lin)/k(nick)) revealed concerted mechanisms for nicking and subsequent linearization of plasmid DNA for all of the Rev-coupled M-chelates, consistent with higher DNA residency times for the Rev-coupled M-chelates. Observed rates for Rev-coupled M-chelates were less skewed by differing DNA-binding affinities than for M-chelates lacking Rev, as a result of the narrow range of DNA-binding affinities observed, and therefore relationships between DNA nuclease activity and other catalyst properties, such as coordination unsaturation, the ability to consume ascorbic acid and generate diffusible radicals, and the identity of the metal center, are now clearly illustrated in light of the similar DNA-binding affinities of all M-chelate-Rev complexes. This work

  5. Large-scale shell model study of the newly found isomer in 136La

    Science.gov (United States)

    Teruya, E.; Yoshinaga, N.; Higashiyama, K.; Nishibata, H.; Odahara, A.; Shimoda, T.

    2016-07-01

    The doubly-odd nucleus 136La is theoretically studied in terms of a large-scale shell model. The energy spectrum and transition rates are calculated and compared with the most updated experimental data. The isomerism is investigated for the first 14+ state, which was found to be an isomer in the previous study [Phys. Rev. C 91, 054305 (2015), 10.1103/PhysRevC.91.054305]. It is found that the 14+ state becomes an isomer due to a band crossing of two bands with completely different configurations. The yrast band with the (ν h11/2 -1⊗π h11 /2 ) configuration is investigated, revealing a staggering nature in M 1 transition rates.

  6. Modelling the structure factors and pair distribution functions of amorphous germanium, silicon and carbon

    Energy Technology Data Exchange (ETDEWEB)

    Dalgic, Seyfettin; Gonzalez, Luis Enrique; Baer, Shalom; Silbert, Moises

    2002-12-01

    We present the results of calculations of the static structure factor S(k) and the pair distribution function g(r) of the tetrahedral amorphous semiconductors germanium, silicon and carbon using the structural diffusion model (SDM). The results obtained with the SDM for S(k) and g(r) are of comparable quality with those obtained by the unconstrained Reverse Monte Carlo simulations and existing ab initio molecular dynamics simulations for these systems. We have found that g(r) exhibits a small peak, or shoulder, a weak remnant of the prominent third neighbour peak present in the crystalline phase of these systems. This feature has been experimentally found to be present in recently reported high energy X-ray experiments of amorphous silicon (Phys. Rev. B 60 (1999) 13520), as well as in the previous X-ray diffraction of as-evaporated amorphous germanium (Phys. Rev. B 50 (1994) 539)

  7. Bose-Hubbard models with staggered flux: Quantum phases, collective excitation, and tricriticality

    Science.gov (United States)

    Yao, Juan; Zhang, Shizhong

    2014-08-01

    We study the quantum phases of a Bose-Hubbard model with staggered magnetic flux in two dimensions, as was realized recently [M. Aidelsburger, M. Atala, M. Lohse, J. T. Barreiro, B. Paredes, and I. Bloch, Phys. Rev. Lett. 107, 255301 (2011), 10.1103/PhysRevLett.107.255301]. Within mean-field theory, we show how the structure of the condensates evolves from the weak- to the strong-coupling limit, exhibiting a tricritical point at the Mott-superfluid transition. Nontrivial topological structures (Dirac points) in the quasiparticle (hole) excitations in the Mott state are found within random phase approximation and we discuss how interaction modifies their structures. The excitation gap in the Mott state closes at different k points when approaching the superfluid states, which is consistent with the findings of mean-field theory.

  8. Biological transportation networks: Modeling and simulation

    KAUST Repository

    Albi, Giacomo

    2015-09-15

    We present a model for biological network formation originally introduced by Cai and Hu [Adaptation and optimization of biological transport networks, Phys. Rev. Lett. 111 (2013) 138701]. The modeling of fluid transportation (e.g., leaf venation and angiogenesis) and ion transportation networks (e.g., neural networks) is explained in detail and basic analytical features like the gradient flow structure of the fluid transportation network model and the impact of the model parameters on the geometry and topology of network formation are analyzed. We also present a numerical finite-element based discretization scheme and discuss sample cases of network formation simulations.

  9. Determining the REV for Fracture Rock Mass Based on Seepage Theory

    Directory of Open Access Journals (Sweden)

    Lili Zhang

    2017-01-01

    Full Text Available Seepage problems of the fractured rock mass have always been a heated topic within hydrogeology and engineering geology. The equivalent porous medium model method is the main method in the study of the seepage of the fractured rock mass and its engineering application. The key to the method is to determine a representative elementary volume (REV. The FractureToKarst software, that is, discrete element software, is a main analysis tool in this paper and developed by a number of authors. According to the standard of rock classification established by ISRM, this paper aims to discuss the existence and the size of REV of fractured rock masses with medium tractility and provide a general method to determine the existence of REV. It can be gleaned from the study that the existence condition of fractured rock mass with medium tractility features average fracture spacing smaller than 0.6 m. If average fracture spacing is larger than 0.6 m, there is no existence of REV. The rationality of the model is verified by a case study. The present research provides a method for the simulation of seepage field in fissured rocks.

  10. Administrative Circular N° 26 (Rev.  5) - November 2004

    CERN Multimedia

    Human Resources Department

    2004-01-01

    Procedure governing the career evolution of staff members The introduction of an electronic individual appraisal report form via EDH for the MAPS exercise entails some modifications to Administrative Circular N° 26 (Rev. 4). The revised version (Rev. 5) is available in departmental secretariats as well as on the Web at the following address: http://cern.ch/hr-web/internal/admin_services/admincirc/listadmincirc.asp Human Resources Department Tel. 74128

  11. Reply to "comment on 'Monte Carlo simulations for a Lotka-type model with reactant surface diffusion and interactions' ".

    Science.gov (United States)

    Kuzovkov, V N; Zvejnieks, G

    2002-03-01

    We reply to the Comment by Zhdanov [preceding paper, Phys. Rev. E 65, blacksquare, square, filled (2002)] on our recent paper [G. Zvejnieks and V. N. Kuzovkov, Phys. Rev. E 63, 051104 (2001)]. We demonstrate that our quite different viewpoints result, in fact, entirely from nonunique definitions of the master equation, which has nothing to do with neglecting important physical principles, as Zhdanov claims.

  12. Quantum Kramers model: Corrections to the linear response theory for continuous bath spectrum

    Science.gov (United States)

    Rips, Ilya

    2017-01-01

    Decay of the metastable state is analyzed within the quantum Kramers model in the weak-to-intermediate dissipation regime. The decay kinetics in this regime is determined by energy exchange between the unstable mode and the stable modes of thermal bath. In our previous paper [Phys. Rev. A 42, 4427 (1990), 10.1103/PhysRevA.42.4427], Grabert's perturbative approach to well dynamics in the case of the discrete bath [Phys. Rev. Lett. 61, 1683 (1988), 10.1103/PhysRevLett.61.1683] has been extended to account for the second order terms in the classical equations of motion (EOM) for the stable modes. Account of the secular terms reduces EOM for the stable modes to those of the forced oscillator with the time-dependent frequency (TDF oscillator). Analytic expression for the characteristic function of energy loss of the unstable mode has been derived in terms of the generating function of the transition probabilities for the quantum forced TDF oscillator. In this paper, the approach is further developed and applied to the case of the continuous frequency spectrum of the bath. The spectral density functions of the bath of stable modes are expressed in terms of the dissipative properties (the friction function) of the original bath. They simplify considerably for the one-dimensional systems, when the density of phonon states is constant. Explicit expressions for the fourth order corrections to the linear response theory result for the characteristic function of the energy loss and its cumulants are obtained for the particular case of the cubic potential with Ohmic (Markovian) dissipation. The range of validity of the perturbative approach in this case is determined (γ /ωbrate for the quantum and for the classical Kramers models. Results for the classical escape rate are in very good agreement with the numerical simulations for high barriers. The results can serve as an additional proof of the robustness and accuracy of the linear response theory.

  13. Preface: phys. stat. sol (a) 203/9

    Science.gov (United States)

    Duewski, P.; Bristowe, P.; Maurice, J.-L.; Komninou, P.

    2006-07-01

    This special issue contains a selection of papers that were presented at a symposium on Interfacial Processes and Properties of Advanced Materials (IPAM05) held at the E-MRS Fall Meeting, Warsaw, Poland on 5-7 September 2005. The symposium was conceived and inspired by the success of its predecessor (IPAM04) held at the University of Caen, France in June 2004.The symposium attracted over sixty contributions and was organized around five areas: Interfaces and dislocations in compound semiconductors, Gate oxide interfaces, Interfaces and defects in electroceramics, Metal-metal interfaces and interfacial modeling, and Interfaces in nano-structured and amorphous thin-film systems. The focus was on the influence of buried interfaces on the functionality of various electronic and opto-electronic devices such as lasers, ferroelectric memories, CMOS and magnetic disks. Therefore the materials addressed at the symposium included compound semiconductors (e.g. GaN, CdTe, ZnO), perovskites (e.g. SrTiO3), dielectrics (e.g. HfO2, SiO2, Al2O3), and metals (e.g. Fe/V superlattices). The aim of the symposium was to bring together leading interface experts, both experimental and theoretical, to explore the connection between interfacial properties (atomic and electronic structure, segregation, diffusion, kinetics) and materials performance in a device application. Papers were presented that described the use of a variety of sophisticated experimental techniques to explore the interfacial properties including HRTEM, X-ray high-resolution diffraction, Raman spectroscopy, STM, AFM, PL spectroscopy, SIMS and electrical and magnetic measurements. The theoretical work included applications of density functional theory, atomistic simulations, dislocation theory and finite element modeling. The program stimulated many exciting and productive discussions between experimentalists and theorists. The ultimate objective was to improve our knowledge of the role of interfaces on the properties of

  14. Preface: phys. stat. sol. (b) 242/9

    Science.gov (United States)

    Sánchez, Maria

    2005-07-01

    The XVII Latin American Symposium on Solid State Physics took place in the conference rooms of the Convent San Francisco de Asis, in the heart of the Old Havana. The sixteen previous editions were organized in eight different countries; the last two were in Colombia (Cartagena, 1999) and Venezuela (Merida, 2002). After eighteen years the meeting came back to Havana in 2004.The program topics included: Surfaces and interfaces analysis; Spintronics; Magnetism; Materials and energy; Ab-initio methods, simulations and modeling in solids; Nanophysics, nanomaterials and nanotechnology; New materials, properties and applications; Preparation of materials, thin films and characterization; High temperature superconductivity; Techniques of structural analysis in solids. The program included 6 plenary talks, 13 invited talks, 58 oral presentations (in eight sessions) and 200 poster contributions (in four poster sessions).The meeting attracted more than 200 participants from 14 countries. The physica status solidi Young Researcher Award sponsored by Wiley-VCH was conferred at the meeting. This prize was divided between two participants: Clara Calderón (Study of electrical transport properties of ZnO thin films used as front contact of solar cells) from Colombia and Aim?? Pelaiz Barranco (AC behavior in lanthanum modified PZT ferroelectric ceramics) from Cuba. Special Mentions went to Val??rie Halté (Femtosec-ond dynamics of transmission of gold arrays of sub-wavelength holes) from France, Erick Larramendi Cancio (Cd desorption induced by Zn exposure during atomic layer epitaxy of CdxZn1-xTe) and Julio Cesar Rimada Herrera (Quantum and conversion efficiency calculation of AlGaAs/GaAs multiple quantum well solar cells) from Cuba.Nanostructures and in general low dimensional physics related to different systems was a very hot topic during the meeting. Some talks and presentations were devoted to optoelectronic materials and devices. Characterization of solids by different

  15. Preface: phys. stat. sol. (b) 241/9

    Science.gov (United States)

    Morawetz, Klaus

    2004-07-01

    Modelling and Simulation in Molecular Systems, Mesoscopic Structures, and Material Science was the title of a workshop held at the University of Technology in Chemnitz from 21 to 23 April 2004. This workshop coincided with the 50th birthday of Michael Schreiber. Therefore, the idea to publish a special issue is supported by two good reasons. First, a topical collection is appropriate for giving an overview about a field and to initiate further studies. This is one intention of the present issue. Second, the birthday is a suitable occasion for reflecting on the status of the different fields where Michael Schreiber has been active himself. Motivated by the characteristic name of the workshop (MS4), which expresses the broad range of his activities, the contributions are grouped into three main chapters: Disorder and Interaction, Phase Transitions and Criticality, and Transport Properties.The first part starts with the currently intensively discussed topic of composite Fermions in the paper by B. Kramer et al. This method of rewriting correlations as new quasiparticles has amongst other things the merit of explaining such exciting phenomena as the fractional quantum Hall effect. The methodological questions of Ward identities, causality, and conservation laws are the focus of the systematic investiga-tion in the second article by V. Janis et al. which concentrates on the problem of disorder and configura-tional averaging. The interplay between disorder and correlation is treated in the third contribution by C. Schuster et al., where different theoretical methods are tested on the problem of Friedel oscillations within the one-dimensional Heisenberg and Hubbard model. In the next contribution, M. Berciu et al. focus on localization as one consequence of disorder. The localized and extended electronic states are treated, together with the magnetic degrees of freedom, like spin waves. One of the astonishing consequence of localiza-tion is the observation of resonant

  16. Pärnu REV sai kuuekümneseks / Andres Mets

    Index Scriptorium Estoniae

    Mets, Andres, 1943-

    2004-01-01

    Ehitusfirma Pärnu REV tähistab ainsa toimiva ja sisu muutnud remondi- ja ehitusvalitsusena kuuekümneaastast juubelit. Kommenteerivad REV-i nõukogu esimees Raivo Pulk ja REV-i juhataja Uno Kõressaar

  17. Pärnu REV sai kuuekümneseks / Andres Mets

    Index Scriptorium Estoniae

    Mets, Andres, 1943-

    2004-01-01

    Ehitusfirma Pärnu REV tähistab ainsa toimiva ja sisu muutnud remondi- ja ehitusvalitsusena kuuekümneaastast juubelit. Kommenteerivad REV-i nõukogu esimees Raivo Pulk ja REV-i juhataja Uno Kõressaar

  18. Exploring magnetized liner inertial fusion with a semi-analytic model

    CERN Document Server

    McBride, R D; Vesey, R A; Gomez, M R; Sefkow, A B; Hansen, S B; Knapp, P F; Schmit, P F; Geissel, M; Harvey-Thompson, A J; Jennings, C A; Harding, E C; Awe, T J; Rovang, D C; Hahn, K D; Martin, M R; Cochrane, K R; Peterson, K J; Rochau, G A; Porter, J L; Stygar, W A; Campbell, E M; Nakhleh, C W; Herrmann, M C; Cuneo, M E; Sinars, D B

    2016-01-01

    In this paper, we explore magnetized liner inertial fusion (MagLIF) [S. A. Slutz et al., Phys. Plasmas 17, 056303 (2010)] using a semi-analytic model [R. D. McBride and S. A. Slutz, Phys. Plasmas 22, 052708 (2015)]. Specifically, we present simulation results from this model that: (a) illustrate the parameter space, energetics, and overall system efficiencies of MagLIF; (b) demonstrate the dependence of radiative loss rates on the radial fraction of the fuel that is preheated; (c) explore some of the recent experimental results of the MagLIF program at Sandia National Laboratories [M. R. Gomez et al., Phys. Rev. Lett. 113, 155003 (2014)]; (d) highlight the experimental challenges presently facing the MagLIF program; and (e) demonstrate how increases to the preheat energy, fuel density, axial magnetic field, and drive current could affect future MagLIF performance.

  19. Exploring magnetized liner inertial fusion with a semi-analytic model

    Energy Technology Data Exchange (ETDEWEB)

    McBride, R. D.; Slutz, S. A.; Vesey, R. A.; Gomez, M. R.; Sefkow, A. B.; Hansen, S. B.; Knapp, P. F.; Schmit, P. F.; Geissel, M.; Harvey-Thompson, A. J.; Jennings, C. A.; Harding, E. C.; Awe, T. J.; Rovang, D. C.; Hahn, K. D.; Martin, M. R.; Cochrane, K. R.; Peterson, K. J.; Rochau, G. A.; Porter, J. L. [Sandia National Laboratories, Albuquerque, New Mexico 87185 (United States); and others

    2016-01-15

    In this paper, we explore magnetized liner inertial fusion (MagLIF) [S. A. Slutz et al., Phys. Plasmas 17, 056303 (2010)] using a semi-analytic model [R. D. McBride and S. A. Slutz, Phys. Plasmas 22, 052708 (2015)]. Specifically, we present simulation results from this model that: (a) illustrate the parameter space, energetics, and overall system efficiencies of MagLIF; (b) demonstrate the dependence of radiative loss rates on the radial fraction of the fuel that is preheated; (c) explore some of the recent experimental results of the MagLIF program at Sandia National Laboratories [M. R. Gomez et al., Phys. Rev. Lett. 113, 155003 (2014)]; (d) highlight the experimental challenges presently facing the MagLIF program; and (e) demonstrate how increases to the preheat energy, fuel density, axial magnetic field, and drive current could affect future MagLIF performance.

  20. HIV-1 Rev protein specifies the viral RNA export pathway by suppressing TAP/NXF1 recruitment.

    Science.gov (United States)

    Taniguchi, Ichiro; Mabuchi, Naoto; Ohno, Mutsuhito

    2014-06-01

    Nuclear RNA export pathways in eukaryotes are often linked to the fate of a given RNA. Therefore, the choice of export pathway should be well-controlled to avoid an unfavorable effect on gene expression. Although some RNAs could be exported by more than one pathway, little is known about how the choice is regulated. This issue is highlighted when the human immunodeficiency virus type 1 (HIV-1) Rev protein induces the export of singly spliced and unspliced HIV-1 transcripts. How these RNAs are exported is not well understood because such transcripts should have the possibility of utilizing CRM1-dependent export via Rev or cellular TAP/NXF1-dependent export via the transcription/export (TREX) complex, or both. Here we found that Rev suppressed TAP/NXF1-dependent export of model RNA substrates that recapitulated viral transcripts. In this effect, Rev interacted with the cap-binding complex and inhibited the recruitment of the TREX complex. Thus, Rev controls the identity of the factor occupying the cap-proximal region that determines the RNA export pathway. This ribonucleoprotein remodeling activity of Rev may favor viral gene expression.

  1. Delayed Random Walks: Modeling Human Posture Control

    Science.gov (United States)

    Ohira, Toru

    1998-03-01

    We consider a phenomenological description of a noisy trajectory which appears on a stabiliogram platform during human postural sway. We hypothesize that this trajectory arises due to a mixture of uncontrollable noise and a corrective delayed feedback to an upright position. Based on this hypothesis, we model the process with a biased random walk whose transition probability depends on its position at a fixed time delay in the past, which we call a delayed random walk. We first introduce a very simple model (T. Ohira and J. G. Milton, Phys.Rev.E. 52), 3277, (1995), which can nevertheless capture the rough qualitative features of the two--point mean square displacement of experimental data with reasonable estimation of delay time. Then, we discuss two approaches toward better capturing and understanding of the experimental data. The first approach is an extension of the model to include a spatial displacement threshold from the upright position below which no or only weak corrective feedback motion takes place. This can be incorporated into an extended delayed random walk model. Numerical simulations show that this extended model can better capture the three scaling region which appears in the two--point mean square displacement. The other approach studied the autocorrelation function of the experimental data, which shows oscillatory behavior. We recently investigated a delayed random walk model whose autocorrelation function has analytically tractable oscillatory behavior (T. Ohira, Phys.Rev.E. 55), R1255, (1997). We discuss how this analytical understanding and its application to delay estimation (T. Ohira and R. Sawatari, Phys.Rev.E. 55), R2077, (1997) could possibly be used to further understand the postural sway data.

  2. Hidden variable models for quantum mechanics can have local parts

    CERN Document Server

    Larsson, Jan-Ake

    2009-01-01

    We present an explicit nonlocal nonsignaling model which has a nontrivial local part and is compatible with quantum mechanics. This model constitutes a counterexample to Colbeck and Renner's statement [Phys. Rev. Lett. 101, 050403 (2008)] that "any hidden variable model can only be compatible with quantum mechanics if its local part is trivial". Furthermore, we examine Colbeck and Renner's definition of "local part" and find that, in the case of models reproducing the quantum predictions for the singlet state, it is a restriction equivalent to the conjunction of nonsignaling and trivial local part.

  3. Ordering dynamics of microscopic models with nonconserved order parameter of continuous symmetry

    DEFF Research Database (Denmark)

    Zhang, Z.; Mouritsen, Ole G.; Zuckermann, Martin J.

    1993-01-01

    Numerical Monte Carlo temperature-quenching experiments have been performed on two three-dimensional classical lattice models with continuous ordering symmetry: the Lebwohl-Lasher model [Phys. Rev. A 6, 426 (1972)] and the ferromagnetic isotropic Heisenberg model. Both models describe a transition...... from a disordered phase to an orientationally ordered phase of continuous symmetry. The Lebwohl-Lasher model accounts for the orientational ordering properties of the nematic-isotropic transition in liquid crystals and the Heisenberg model for the ferromagnetic-paramagnetic transition in magnetic...

  4. Criticality in Two-Variable Earthquake Model on a Random Graph

    Institute of Scientific and Technical Information of China (English)

    SUN Fan; ZHANG Duan-Ming

    2008-01-01

    A two-variable earthquake model on a quenched random graph is established here. It can be seen as a generalization of the OFC models. We numerically study the critical behavior of the model when the system is nonconservative: the result indicates that the model exhibits self-organized criticality deep within the nonconservative regime. The probability distribution for avalanche size obeys finite size scaling. We compare our model with the model introduced by Stefano Lise and Maya Paczuski [Phys. Rev. Lett. 88 (2002) 228301], it is proved that they are not in the same universality class.

  5. HIV-1 tat and rev upregulates osteoclast bone resorption

    Directory of Open Access Journals (Sweden)

    Nicholas Chew

    2014-11-01

    Full Text Available Introduction: Disruption in bone homeostasis with increased osteoclastic resorption may lead to osteoporosis. HIV tat has been found to increase differentiation of precursor cells into osteoclast (OC (1. Presence of soluble HIV proteins in virally suppressed HIV patients on ART may drive a bone resorption phenotype. We investigated the role of soluble HIV proteins (tat, gp120 Mn and Bal, rev and p55-gag on osteoclastogenesis and OC resorptive capacity. Methods: Mouse monocyte RAW 264.7 cells were cultured in vitro and induced to differentiate into OCs with 50 ng/mL RANKL and 25 ng/mL mCSF. Medium was supplemented with 100 ng/mL of recombinant HIV tat, gp120 (Mn and Bal, rev, nef and p55-gag, respectively, with zolendronate as negative control. Differentiated OCs were stained for TRAP and counted. OC resorption function was examined by culturing differentiated OCs (in the presence of respective HIV proteins on dentin-coated plates and examining the following (i sealing zone formation, (ii volume of resorption pits and (iii area of resorption pits per field using confocal microscopy. Expression of OC specific genes including NFATc1 and cathepsin K was investigated by qPCR. Reactive oxygen species (ROS production is essential in RANKL-induced OC differentiation (2,3; effect of these proteins on ROS production was assessed using the fluorescent H2DCFH-DA. Mean fluorescence intensity was then measured by flow cytometry. TNFα production by OC precursors when incubated with tat and rev was measured by ELISA. Results: Tat and rev treatment was associated with increased OC formation by 70 and 26%, respectively (p<0.01, relative to control, while zolendronate significantly inhibited OC formation by 75%. Gp120 Mn and Bal, nef and p55-gag treatment had no effect on OC differentiation. Interestingly, neither tat nor rev treatment caused significant increases in sealing zone formation but increased dentin resorption pit area by 28 and 19%, respectively, and

  6. Administrative Circular No. 26 (Rev. 7) – May 2007

    CERN Multimedia

    HR Department

    2007-01-01

    Recognition of Merit of Staff Members Administrative Circular No. 26 (Rev. 7) is now available on the intranet site of the Human Resources Department. This circular cancels and replaces Administrative Circular No. 26 (Rev. 6) - Procedures governing the career development of staff members. Copies will shortly be available in Departmental secretariats. If you require any additional information on the new staff-member merit assessment and recognition system, you may consult the FAQ, which has been available on the Human Resources Department intranet site since February 2007. Human Resources Department Tel. 78003

  7. Cellular automata models for synchronized traffic flow

    CERN Document Server

    Jiang Rui

    2003-01-01

    This paper presents a new cellular automata model for describing synchronized traffic flow. The fundamental diagrams, the spacetime plots and the 1 min average data have been analysed in detail. It is shown that the model can describe the outflow from the jams, the light synchronized flow as well as heavy synchronized flow with average speed greater than approximately 24 km h sup - sup 1. As for the synchronized flow with speed lower than 24 km h sup - sup 1 , it is unstable and will evolve into the coexistence of jams, free flow and light synchronized flow. This is consistent with the empirical findings (Kerner B S 1998 Phys. Rev. Lett. 81 3797).

  8. Phase I Hydrologic Data for the Groundwater Flow and Contaminant Transport Model of Corrective Action Unit 97: Yucca Flat/Climax Mine, Nevada Test Site, Nye County, Nevada, Rev. No.: 0

    Energy Technology Data Exchange (ETDEWEB)

    John McCord

    2006-06-01

    The U.S. Department of Energy (DOE), National Nuclear Security Administration Nevada Site Office (NNSA/NSO) initiated the Underground Test Area (UGTA) Project to assess and evaluate the effects of the underground nuclear weapons tests on groundwater beneath the Nevada Test Site (NTS) and vicinity. The framework for this evaluation is provided in Appendix VI, Revision No. 1 (December 7, 2000) of the Federal Facility Agreement and Consent Order (FFACO, 1996). Section 3.0 of Appendix VI ''Corrective Action Strategy'' of the FFACO describes the process that will be used to complete corrective actions specifically for the UGTA Project. The objective of the UGTA corrective action strategy is to define contaminant boundaries for each UGTA corrective action unit (CAU) where groundwater may have become contaminated from the underground nuclear weapons tests. The contaminant boundaries are determined based on modeling of groundwater flow and contaminant transport. A summary of the FFACO corrective action process and the UGTA corrective action strategy is provided in Section 1.5. The FFACO (1996) corrective action process for the Yucca Flat/Climax Mine CAU 97 was initiated with the Corrective Action Investigation Plan (CAIP) (DOE/NV, 2000a). The CAIP included a review of existing data on the CAU and proposed a set of data collection activities to collect additional characterization data. These recommendations were based on a value of information analysis (VOIA) (IT, 1999), which evaluated the value of different possible data collection activities, with respect to reduction in uncertainty of the contaminant boundary, through simplified transport modeling. The Yucca Flat/Climax Mine CAIP identifies a three-step model development process to evaluate the impact of underground nuclear testing on groundwater to determine a contaminant boundary (DOE/NV, 2000a). The three steps are as follows: (1) Data compilation and analysis that provides the necessary modeling

  9. Hydrodynamic description of spin Calogero-Sutherland model

    Science.gov (United States)

    Abanov, Alexander; Kulkarni, Manas; Franchini, Fabio

    2009-03-01

    We study a non-linear collective field theory for an integrable spin-Calogero-Sutherland model. The hydrodynamic description of this SU(2) model in terms of charge density, charge velocity and spin currents is used to study non-perturbative solutions (solitons) and examine their correspondence with known quantum numbers of elementary excitations [1]. A conventional linear bosonization or harmonic approximation is not sufficient to describe, for example, the physics of spin-charge (non)separation. Therefore, we need this new collective bosonic field description that captures the effects of the band curvature. In the strong coupling limit [2] this model reduces to integrable SU(2) Haldane-Shastry model. We study a non-linear coupling of left and right spin currents which form a Kac-Moody algebra. Our quantum hydrodynamic description for the spin case is an extension for the one found in the spinless version in [3].[3pt] [1] Y. Kato,T. Yamamoto, and M. Arikawa, J. Phys. Soc. Jpn. 66, 1954-1961 (1997).[0pt] [2] A. Polychronakos, Phys Rev Lett. 70,2329-2331(1993).[0pt] [3] A.G.Abanov and P.B. Wiegmann, Phys Rev Lett 95, 076402(2005)

  10. Comment on “A study of vertical and in-plane electron mobility due to interface roughness scattering at low temperature in InAs-GaSb superlattices” [J. Appl. Phys. 114, 053712 (2013)

    Energy Technology Data Exchange (ETDEWEB)

    Szmulowicz, F., E-mail: Frank.Szmulowicz.ctr@wpafb.af.mil [University of Dayton Research Institute, 300 College Park Ave., Dayton, Ohio 45469-0072 (United States)

    2014-04-14

    The purpose of this comment is to point out that the paper by Safa, Asgari, and Faraone [J. Appl. Phys. 114, 053712 (2013)] (SAF) on electronic transport in superlattices contains a number of errors in physics and execution. By dealing with a finite number of periods and forcing the wave function to be zero at the upper and lower boundaries of the superlattice stack, SAF have turned the system into a quantum well for which the momentum along the growth axis is not a good quantum number, so that the bands in the growth direction are flat and the corresponding carrier velocities and vertical mobilities are zero. A number of other errors allow the authors to get nonzero results and to reach conclusions that qualitatively mirror those of Szmulowicz, Haugan, Elhamri, and Brown [Phys. Rev. B 84, 155307 (2011)].

  11. Comment on "A study of vertical and in-plane electron mobility due to interface roughness scattering at low temperature in InAs-GaSb superlattices" [J. Appl. Phys. 114, 053712 (2013)

    Science.gov (United States)

    Szmulowicz, F.

    2014-04-01

    The purpose of this comment is to point out that the paper by Safa, Asgari, and Faraone [J. Appl. Phys. 114, 053712 (2013)] (SAF) on electronic transport in superlattices contains a number of errors in physics and execution. By dealing with a finite number of periods and forcing the wave function to be zero at the upper and lower boundaries of the superlattice stack, SAF have turned the system into a quantum well for which the momentum along the growth axis is not a good quantum number, so that the bands in the growth direction are flat and the corresponding carrier velocities and vertical mobilities are zero. A number of other errors allow the authors to get nonzero results and to reach conclusions that qualitatively mirror those of Szmulowicz, Haugan, Elhamri, and Brown [Phys. Rev. B 84, 155307 (2011)].

  12. Intermolecular masking of the HIV-1 Rev NLS by the cellular protein HIC: novel insights into the regulation of Rev nuclear import.

    LENUS (Irish Health Repository)

    Gu, Lili

    2011-01-01

    The HIV-1 regulatory protein Rev, which is essential for viral replication, mediates the nuclear export of unspliced viral transcripts. Rev nuclear function requires active nucleocytoplasmic shuttling, and Rev nuclear import is mediated by the recognition of its Nuclear Localisation Signal (NLS) by multiple import factors, which include transportin and importin β. However, it remains unclear which nuclear import pathway(s) predominate in vivo, and the cellular environment that modulates Rev nucleocytoplasmic shuttling remains to be characterised.

  13. Wind Farm Wake: The Horns Rev Photo Case

    DEFF Research Database (Denmark)

    Hasager, Charlotte Bay; Rasmussen, Leif; Peña, Alfredo

    2013-01-01

    The aim of the paper is to examine the nowadays well-known wind farm wake photographs taken on 12 February 2008 at the offshore Horns Rev 1 wind farm. The meteorological conditions are described from observations from several satellite sensors quantifying clouds, surface wind vectors and sea...

  14. Revised Safety Instruction NO. 4 (IS4 REV.)

    CERN Multimedia

    2006-01-01

    Please note that the revised safety instruction no. 4 (IS4 REV.), entitled 'Safety Inspections' is available on the web at the following url: https://edms.cern.ch/file/335741/LAST_RELEASED/E_IS4.pdf Paper copies can be obtained from the SC unit secretariat. SC Secretariat e-mail: sc.secretariat@cern.ch

  15. Revised Safety Instruction NO. 4 (IS4 REV.)

    CERN Multimedia

    SC Secretariat

    2006-01-01

    Please note that the revised safety instruction No. 4 (IS4 REV.), entitled 'Safety Inspections' is available on the web at the following url: https://edms.cern.ch/file/335741/LAST_RELEASED/E_IS4.pdf Paper copies can be obtained from the SC unit secretariat. SC Secretariat e-mail: sc.secretariat@cern.ch

  16. Revised Safety Instruction NO. 4 (IS4 REV.)

    CERN Multimedia

    2006-01-01

    Please note that the revised safety instruction no. 4 (IS4 REV.), entitled 'Safety Inspections' is available on the web at the following url: https://edms.cern.ch/file/335741/LAST_RELEASED/E_IS4.pdf Paper copies can be obtained from the SC unit secretariat. SC Secretariat sc.secretariat@cern.ch

  17. Wind Farm Wake: The 2016 Horns Rev Photo Case

    DEFF Research Database (Denmark)

    Hasager, Charlotte Bay; Nygaard, Nicolai Gayle; Volker, Patrick

    2017-01-01

    Offshore wind farm wakes were observed and photographed in foggy conditions at Horns Rev 2 on 25 January 2016 at 12:45 UTC. These new images show highly contrasting conditions regarding the wind speed, turbulence intensity, atmospheric stability, weather conditions and wind farm wake development...

  18. A comparative study between EGB gravity and GTR by modeling compact stars

    Energy Technology Data Exchange (ETDEWEB)

    Bhar, Piyali [Government General Degree College, Department of Mathematics, Hooghly, West Bengal (India); Govender, Megan [Durban University of Technology, Department of Mathematics, Faculty of Applied Sciences, Durban (South Africa); Sharma, Ranjan [P. D. Women' s College, Department of Physics, Jalpaiguri (India)

    2017-02-15

    In this paper we utilise the Krori-Barua ansatz to model compact stars within the framework of Einstein-Gauss-Bonnet (EGB) gravity. The thrust of our investigation is to carry out a comparative analysis of the physical properties of our models in EGB and classical general relativity theory with the help of graphical representation. From our analysis we have shown that the central density and central pressure of EGB star model is higher than the GTR star model. The most notable feature is that for both GTR and the EGB star model the compactness factor crosses the Buchdahl (Phys Rev 116:1027, 1959) limit. (orig.)

  19. Comment on “On the quantum theory of molecules” [J. Chem. Phys. 137, 22A544 (2012)

    Energy Technology Data Exchange (ETDEWEB)

    Sutcliffe, Brian T., E-mail: bsutclif@ulb.ac.be [Service de Chimie quantique et Photophysique, Université Libre de Bruxelles, B-1050 Bruxelles (Belgium); Woolley, R. Guy [School of Science and Technology, Nottingham Trent University, Nottingham NG11 8NS (United Kingdom)

    2014-01-21

    In our previous paper [B. T. Sutcliffe and R. G. Woolley, J. Chem. Phys. 137, 22A544 (2012)] we argued that the Born-Oppenheimer approximation could not be based on an exact transformation of the molecular Schrödinger equation. In this Comment we suggest that the fundamental reason for the approximate nature of the Born-Oppenheimer model is the lack of a complete set of functions for the electronic space, and the need to describe the continuous spectrum using spectral projection.

  20. Continuum of quanta in the final theory. Model of spiral fields. Basic ideas for a compatible physics and a consistent nature science. 4. rev. ed.; Quantenkontinuum in der Finaltheorie. Spiralfeldmodell. Grundgedanken fuer eine Kompatible Physik und eine Konsistente Naturwissenschaft

    Energy Technology Data Exchange (ETDEWEB)

    Hartje, Udo Albert Juergen

    2009-07-01

    solution of the puzzle around the 'Dualism of Waves and Particles'. Structures of matter do not consist of any a priori, i.e. out the beginning existing tiniest primordial particles that secondarily swings; but they generate themselves from radiation which does not interrupt their light-fast movement in the interior of particles; and therefore it remains radiation-like. The circulation in itself creates locality; without that the radiation lost their dynamics; and without that this radiation must itself change into electrons: with their secondary turn in the orbital path. The Classic Physics and the Quantum Physics amalgamate into the 'Spiral Field Model' (Model of Spiral Fields). Classic Physics and the Quantum Physics merge in a Model of Spiral Fields into a paramount thought building with a new imagination for radiation and particles. Molecules, atoms and seedless particles have to be analyzed on the new basis. The rich fundus of proven knowledge will help. Problems of the natural sciences which do not find any immediate explanation should be taken in relation to the new thoughts; therewith will the special aspects visible. A single human is not able to it in view of the gigantic range of the accumulated knowledge. (orig.)

  1. Lattice Boltzmann modeling of boiling heat transfer: The boiling curve and the effects of wettability

    OpenAIRE

    Li, Q; Kang, Q. J.; Francois, M. M.; He, Y. L.; Luo, K. H.

    2015-01-01

    A hybrid thermal lattice Boltzmann (LB) model is presented to simulate thermal multiphase flows with phase change based on an improved pseudopotential LB approach [Q. Li, K. H. Luo, and X. J. Li, Phys. Rev. E 87, 053301 (2013)]. The present model does not suffer from the spurious term caused by the forcing-term effect, which was encountered in some previous thermal LB models for liquid-vapor phase change. Using the model, the liquid-vapor boiling process is simulated. The boiling curve togeth...

  2. Intermolecular masking of the HIV-1 Rev NLS by the cellular protein HIC: Novel insights into the regulation of Rev nuclear import.

    LENUS (Irish Health Repository)

    Gu, Lili

    2011-03-14

    Abstract Background The HIV-1 regulatory protein Rev, which is essential for viral replication, mediates the nuclear export of unspliced viral transcripts. Rev nuclear function requires active nucleocytoplasmic shuttling, and Rev nuclear import is mediated by the recognition of its Nuclear Localisation Signal (NLS) by multiple import factors, which include transportin and importin β. However, it remains unclear which nuclear import pathway(s) predominate in vivo, and the cellular environment that modulates Rev nucleocytoplasmic shuttling remains to be characterised. Results In our study, we have identified the cellular protein HIC (Human I-mfa domain-Containing protein) as a novel interactor of HIV-1 Rev. We demonstrate that HIC selectively interferes with Rev NLS interaction with importin β and impedes its nuclear import and function, but does not affect Rev nuclear import mediated by transportin. Hence, the molecular determinants mediating Rev-NLS recognition by importin β and transportin appear to be distinct. Furthermore, we have employed HIC and M9 M, a peptide specifically designed to inhibit the transportin-mediated nuclear import pathway, to characterise Rev nuclear import pathways within different cellular environments. Remarkably, we could show that in 293T, HeLa, COS7, Jurkat, U937, THP-1 and CEM cells, Rev nuclear import is cell type specific and alternatively mediated by transportin or importin β, in a mutually exclusive fashion. Conclusions Rev cytoplasmic sequestration by HIC may represent a novel mechanism for the control of Rev function. These studies highlight that the multivalent nature of the Rev NLS for different import receptors enables Rev to adapt its nuclear trafficking strategy.

  3. Intermolecular masking of the HIV-1 Rev NLS by the cellular protein HIC: Novel insights into the regulation of Rev nuclear import

    Directory of Open Access Journals (Sweden)

    Sheehy Noreen

    2011-03-01

    Full Text Available Abstract Background The HIV-1 regulatory protein Rev, which is essential for viral replication, mediates the nuclear export of unspliced viral transcripts. Rev nuclear function requires active nucleocytoplasmic shuttling, and Rev nuclear import is mediated by the recognition of its Nuclear Localisation Signal (NLS by multiple import factors, which include transportin and importin β. However, it remains unclear which nuclear import pathway(s predominate in vivo, and the cellular environment that modulates Rev nucleocytoplasmic shuttling remains to be characterised. Results In our study, we have identified the cellular protein HIC (Human I-mfa domain-Containing protein as a novel interactor of HIV-1 Rev. We demonstrate that HIC selectively interferes with Rev NLS interaction with importin β and impedes its nuclear import and function, but does not affect Rev nuclear import mediated by transportin. Hence, the molecular determinants mediating Rev-NLS recognition by importin β and transportin appear to be distinct. Furthermore, we have employed HIC and M9 M, a peptide specifically designed to inhibit the transportin-mediated nuclear import pathway, to characterise Rev nuclear import pathways within different cellular environments. Remarkably, we could show that in 293T, HeLa, COS7, Jurkat, U937, THP-1 and CEM cells, Rev nuclear import is cell type specific and alternatively mediated by transportin or importin β, in a mutually exclusive fashion. Conclusions Rev cytoplasmic sequestration by HIC may represent a novel mechanism for the control of Rev function. These studies highlight that the multivalent nature of the Rev NLS for different import receptors enables Rev to adapt its nuclear trafficking strategy.

  4. Dynamic Model of Mesoscale Eddies

    Science.gov (United States)

    Dubovikov, Mikhail S.

    2003-04-01

    Oceanic mesoscale eddies which are analogs of well known synoptic eddies (cyclones and anticyclones), are studied on the basis of the turbulence model originated by Dubovikov (Dubovikov, M.S., "Dynamical model of turbulent eddies", Int. J. Mod. Phys.B7, 4631-4645 (1993).) and further developed by Canuto and Dubovikov (Canuto, V.M. and Dubovikov, M.S., "A dynamical model for turbulence: I. General formalism", Phys. Fluids8, 571-586 (1996a) (CD96a); Canuto, V.M. and Dubovikov, M.S., "A dynamical model for turbulence: II. Sheardriven flows", Phys. Fluids8, 587-598 (1996b) (CD96b); Canuto, V.M., Dubovikov, M.S., Cheng, Y. and Dienstfrey, A., "A dynamical model for turbulence: III. Numerical results", Phys. Fluids8, 599-613 (1996c)(CD96c); Canuto, V.M., Dubovikov, M.S. and Dienstfrey, A., "A dynamical model for turbulence: IV. Buoyancy-driven flows", Phys. Fluids9, 2118-2131 (1997a) (CD97a); Canuto, V.M. and Dubovikov, M.S., "A dynamical model for turbulence: V. The effect of rotation", Phys. Fluids9, 2132-2140 (1997b) (CD97b); Canuto, V.M., Dubovikov, M.S. and Wielaard, D.J., "A dynamical model for turbulence: VI. Two dimensional turbulence", Phys. Fluids9, 2141-2147 (1997c) (CD97c); Canuto, V.M. and Dubovikov, M.S., "Physical regimes and dimensional structure of rotating turbulence", Phys. Rev. Lett. 78, 666-669 (1997d) (CD97d); Canuto, V.M., Dubovikov, M.S. and Dienstfrey, A., "Turbulent convection in a spectral model", Phys. Rev. Lett. 78, 662-665 (1997e) (CD97e); Canuto, V.M. and Dubovikov, M.S., "A new approach to turbulence", Int. J. Mod. Phys.12, 3121-3152 (1997f) (CD97f); Canuto, V.M. and Dubovikov, M.S., "Two scaling regimes for rotating Raleigh-Benard convection", Phys. Rev. Letters78, 281-284, (1998) (CD98); Canuto, V.M. and Dubovikov, M.S., "A dynamical model for turbulence: VII. The five invariants for shear driven flows", Phys. Fluids11, 659-664 (1999a) (CD99a); Canuto, V.M., Dubovikov, M.S. and Yu, G., "A dynamical model for turbulence: VIII. IR and UV

  5. Administrative Circular No. 26 (Rev.10) - Recognition of merit

    CERN Multimedia

    2014-01-01

    Administrative Circular No. 26 (Rev. 10) entitled “Recognition of Merit”, approved by the Director-General following discussion at the Standing Concertation Committee meeting of 5 December 2013 and entering into force on 1 January 2014, is available on the intranet site of the Human Resources Department (see here).   This circular is applicable to staff members. It cancels and replaces Administrative Circular No. 26 (Rev. 9) entitled “Recognition of Merit” of December 2011. The circular was revised in order to take into account the work performed in the framework of an elective mandate during the exercise of merit recognition of staff members. In addition, the circular was revised to provide that, in the case of staff members on special leave for professional reasons for a period equal to or longer than half a year, it will no longer be possible to grant an exceptional advancement. Department Head Office HR Department

  6. Administrative Circular No. 23 (Rev. 4) - Special working hours

    CERN Multimedia

    Department Head Office - HR Department

    2016-01-01

    Administrative Circular No. 23 (Rev. 4) entitled "Special working hours", approved by the Director-General following discussion in the Standing Concertation Committee meeting on 22 March 2016, will be available on 1st September 2016 via the following link: https://cds.cern.ch/record/2208539.   This revised circular cancels and replaces Administrative Circular No. 23 (Rev. 3) also entitled "Special working hours" of January 2013. This document contains modifications to reflect the new career structure and ensuring the provision consistent with practice that compensation or remuneration of special working hours performed remotely is possible only in case of emergency.   This circular will enter into force on 1st September 2016.

  7. Operational circular No. 1 (Rev. 1) – Operational circulars

    CERN Multimedia

    HR Department

    2011-01-01

    Operational Circular No. 1 (Rev. 1) is applicable to members of the personnel and other persons concerned. Operational Circular No. 1 (Rev. 1) entitled "Operational circulars", approved following discussion at the Standing Concertation Committee meeting on 4 May 2011, is available on the intranet site of the Human Resources Department: https://hr-docs.web.cern.ch/hr-docs/opcirc/opcirc.asp It cancels and replaces Operational Circular No. 1 entitled "Operational Circulars” of December 1996. This new version clarifies, in particular, that operational circulars do not necessarily arise from the Staff Rules and Regulations, and the functional titles have been updated to bring them into line with the current CERN organigram. Department Head Office  

  8. A model for the generic alpha relaxation in viscous liquids

    DEFF Research Database (Denmark)

    Dyre, Jeppe

    2005-01-01

    . Rev. Lett., 86 (2001) 1271]. Assuming that long-wavelength fluctuations dominate the dynamics, a model for the dielectric alpha relaxation based on the simplest coupling between the density and dipole density fields is proposed here. The model, which is solved in second-order perturbation theory......Dielectric measurements on molecular liquids just above the glass transition indicate that alpha relaxation is characterized by a generic high-frequency loss varying as one over square root of frequency, whereas deviations from this come from one or more low-lying beta processes [Olsen et al., Phys...

  9. Association of Rev-erbα in adipose tissues with Type 2 diabetes mellitus amelioration after gastric bypass surgery in Goto-Kakizaki rats.

    Science.gov (United States)

    Zhang, Rui; Yan, Caifeng; Zhou, Xinrong; Qian, Bangguo; Li, Fuqiang; Sun, Yidan; Shi, Chen; Li, Bing; Saito, Shigeru; Horimoto, Katsuhisa; Zhou, Huarong

    2013-07-15

    We estimated the key molecules related to Type 2 diabetes mellitus (T2DM) in adipose, liver, and muscle tissues, from nonobese diabetic Goto-Kakizaki (GK) rats and their Wistar controls, by computationally analyzing the expression profiles in open source data. With the aid of information from previous reports, Rev-erbα in adipose tissue emerged as one of the most plausible candidates. Here, in animal models, including GK rats surgically treated to ameliorate T2DM, we examined the association of Rev-erbα in adipose tissue with T2DM progression. After analyses of the Rev-erbα mRNA expression in the adipose tissue of our animal models, we compared the Rev-erbα protein expression levels in the adipose, liver, and muscle tissues of GK and Wistar controls at the ages of 1 mo (M), 3M, and 6M. The Rev-erbα protein levels in adipose tissue showed a distinctive pattern, with the negative correlation of an increasing trend in GK rats, and a decreasing trend in Wistar rats during aging, from those in liver and muscle tissues. Moreover, dysregulation of the circadian Rev-erbα expression in the adipose tissue of 6-mo-old GK rats was also observed. In particular, we ameliorated T2DM in GK rats by gastric bypass surgery, and revealed that T2DM amelioration in diabetic GK rats was associated with improved circadian Rev-erbα expression, in a comparison between the surgically treated and untreated GK rats. The roles of Rev-erbα in adipose tissue were further investigated by observations of Rev-erbα-related molecules, with reference to previous reports.

  10. Safety Instruction nº 23 (IS 23 Rev. 3)

    CERN Multimedia

    SC Secretariat

    2005-01-01

    Please note that the revised version of Safety Instruction no 23 (IS 23 rev. 3) entitled "Criteria and standard test methods for the selection of electric cables and wires with respect to fire safety and radiation resistance" is available on the web at the following url: https://edms.cern.ch/document/335745/LAST_RELEASED/ Paper copies can also be obtained from the SC Secretariat, e-mail: sc.secretariat@cern.ch SC Secretariat

  11. International Field Reversible Thermal Connector (RevCon) Challenge

    Science.gov (United States)

    2016-07-01

    AFRL-RY-WP-TR-2016-0108 INTERNATIONAL FIELD REVERSIBLE THERMAL CONNECTOR (RevCon) CHALLENGE Chung-Lung Chen University of...or corporation; or convey any rights or permission to manufacture, use, or sell any patented invention that may relate to them. This report is...DD-MM-YY) 2. REPORT TYPE 3. DATES COVERED (From - To) July 2016 Final 07 November 2013 – 15 March 2016 4. TITLE AND SUBTITLE INTERNATIONAL

  12. RevPAR、GOP率、GOPPAR的联动增长

    Institute of Scientific and Technical Information of China (English)

    陈雪羽

    2007-01-01

    RevPAR,指平均每间可售客房产生的收入,其计算方式是酒店客房的全年营收总额除以全年可供出售的客房总间数,或者用更简化的方式,就是用平均房价乘以平均出租率。

  13. Simulaton of the Avedøreværket Unit 1 Cogeneration Plant with DNA

    DEFF Research Database (Denmark)

    Elmegaard, Brian; Houbak, Niels

    2003-01-01

    The simulator contest proposed for the ECOS 2003 conference has been solved using the DNA energy system simulator. The contest concerns the steam process of the Avedøreværket Unit 1 (AVV1) power plant. The plant is a 250 MWCHP plant with a maximum district heat production of 330 MJ/s. The plant has...... a brief description of the DNA simulator, as well as a short notice on some of the component models used. In particular, there is a small investigation of the difference obtained in the solution depending on the model used for the turbine (isentropic efficiency, polytropic efficiency, or straight...

  14. Examining the justification of superposition model of FePc ; A DMC study

    CERN Document Server

    Ichibha, Tom; Hongo, Kenta; Maezono, Ryo

    2016-01-01

    We have applied CASSCF-DMC to evaluate relative stabilities of the possible electronic configurations of an isolated FePc under $D_{4h}$ symmetry. It predicts $A_{2g}$ ground state, supporting preceding DFT studies,[J. Chem. Phys. 114, 9780 (2001), Appl. Phys. 95, 165 (2009), Phys. Rev. B 85, 235129 (2012)] with confidence overcoming the ambiguity about exchange-correlation (XC) functionals. By comparing DMC with several XC, we clarified the importance of the short range exchange to describe the relative stability. We examined why the predicted $A_{2g}$ is excluded from possible ground states in the recent ligand field based model.[J. Chem. Phys. 138, 244308 (2013)] Simplified assumptions made in the superposition model [Rep. Prog. Phys. 52, 699 (1989)] are identified to give unreasonably less energy gain for $A_{2g}$ when compared with the reality. The state is found to have possible reasons for the stabilization, reducing the occupations from an unstable anti-bonding orbital, preventing double occupancies i...

  15. Towards a unified realistic shell-model Hamiltonian with the monopole-based universal force

    CERN Document Server

    Kaneko, K; Sun, Y; Tazaki, S

    2013-01-01

    We propose a unified realistic shell-model Hamiltonian employing the pairing plus multipole Hamiltonian combined with the monopole interaction constructed starting from the monopole-based universal force by Otsuka it et al. (Phys. Rev. Lett. 104, 012501 (2010)). It is demonstrated that the proposed PMMU model can consistently describe a large amount of spectroscopic data as well as binding energies in the pf and pf5/2g9/2 shell spaces, and could serve as a practical shell model for even heavier mass regions.

  16. Law of Malus and Photon-Photon Correlations A Quasi-Deterministic Analyzer Model

    CERN Document Server

    Dalton, B J

    2001-01-01

    For polarization experiments involving photon counting we introduce a quasi-deterministic eigenstate transition model of the analyzer process. Distributions accumulated one photon at a time, provide a deterministic explanation for the law of Malus. We combine this analyzer model with causal polarization coupling to calculate photon-photon correlations, one photon pair at a time. The calculated correlations exceed the Bell limits and show excellent agreement with the measured correlations of [ A. Aspect, P. Grangier and G. Rogers, Phys. Rev. Lett. 49 91 (1982)]. We discuss why this model exceeds the Bell type limits.

  17. Eighth-order phase-field-crystal model for two-dimensional crystallization

    OpenAIRE

    Jaatinen, A.; Ala-Nissilä, Tapio

    2010-01-01

    We present a derivation of the recently proposed eighth-order phase-field crystal model [A. Jaatinen et al., Phys. Rev. E 80, 031602 (2009)] for the crystallization of a solid from an undercooled melt. The model is used to study the planar growth of a two-dimensional hexagonal crystal, and the results are compared against similar results from dynamical density functional theory of Marconi and Tarazona, as well as other phase-field crystal models. We find that among the phase-field crystal mod...

  18. Clusters of classical water models

    Science.gov (United States)

    Kiss, Péter T.; Baranyai, András

    2009-11-01

    The properties of clusters can be used as tests of models constructed for molecular simulation of water. We searched for configurations with minimal energies for a small number of molecules. We identified topologically different structures close to the absolute energy minimum of the system by calculating overlap integrals and enumerating hydrogen bonds. Starting from the dimer, we found increasing number of topologically different, low-energy arrangements for the trimer(3), the tetramer(6), the pentamer(6), and the hexamer(9). We studied simple models with polarizable point dipole. These were the BSV model [J. Brodholt et al., Mol. Phys. 86, 149 (1995)], the DC model [L. X. Dang and T. M. Chang, J. Chem. Phys. 106, 8149 (1997)], and the GCP model [P. Paricaud et al., J. Chem. Phys. 122, 244511 (2005)]. As an alternative the SWM4-DP and the SWM4-NDP charge-on-spring models [G. Lamoureux et al., Chem. Phys. Lett. 418, 245 (2006)] were also investigated. To study the impact of polarizability restricted to the plane of the molecule we carried out calculations for the SPC-FQ and TIP4P-FQ models, too [S. W. Rick et al., J. Chem. Phys. 101, 6141 (1994)]. In addition to them, justified by their widespread use even for near critical or surface behavior calculations, we identified clusters for five nonpolarizable models of ambient water, SPC/E [H. J. C. Berendsen et al., J. Phys. Chem. 91, 6269 (1987)], TIP4P [W. L. Jorgensen et al., J. Chem. Phys. 79, 926 (1983)], TIP4P-EW [H. W. Horn et al., J. Chem. Phys. 120, 9665 (2004)], and TIP4P/2005 [J. L. F. Abascal and C. Vega, J. Chem. Phys. 123, 234505 (2005)]. The fifth was a five-site model named TIP5P [M. W. Mahoney and W. L. Jorgensen, J. Chem. Phys. 112, 8910 (2000)]. To see the impact of the vibrations we studied the flexible SPC model. [K. Toukan and A. Rahman, Phys. Rev. B 31, 2643 (1985)]. We evaluated the results comparing them with experimental data and quantum chemical calculations. The position of the negative

  19. Axisymmetric model of drop spreading on a horizontal surface

    Science.gov (United States)

    Mistry, Aashutosh; Muralidhar, K.

    2015-09-01

    Spreading of an initially spherical liquid drop over a textured surface is analyzed by solving an integral form of the governing equations. The mathematical model extends Navier-Stokes equations by including surface tension at the gas-liquid boundary and a force distribution at the three phase contact line. While interfacial tension scales with drop curvature, the motion of the contact line depends on the departure of instantaneous contact angle from its equilibrium value. The numerical solution is obtained by discretizing the spreading drop into disk elements. The Bond number range considered is 0.01-1. Results obtained for sessile drops are in conformity with limiting cases reported in the literature [J. C. Bird et al., "Short-time dynamics of partial wetting," Phys. Rev. Lett. 100, 234501 (2008)]. They further reveal multiple time scales that are reported in experiments [K. G. Winkels et al., "Initial spreading of low-viscosity drops on partially wetting surfaces," Phys. Rev. E 85, 055301 (2012) and A. Eddi et al., "Short time dynamics of viscous drop spreading," Phys. Fluids 25, 013102 (2013)]. Spreading of water and glycerin drops over fully and partially wetting surfaces is studied in terms of excess pressure, wall shear stress, and the dimensions of the footprint. Contact line motion is seen to be correctly captured in the simulations. Water drops show oscillations during spreading while glycerin spreads uniformly over the surface.

  20. User Instructions for the Systems Assessment Capability, Rev. 1, Computer Codes Volume 3: Utility Codes

    Energy Technology Data Exchange (ETDEWEB)

    Eslinger, Paul W.; Aaberg, Rosanne L.; Lopresti, Charles A.; Miley, Terri B.; Nichols, William E.; Strenge, Dennis L.

    2004-09-14

    This document contains detailed user instructions for a suite of utility codes developed for Rev. 1 of the Systems Assessment Capability. The suite of computer codes for Rev. 1 of Systems Assessment Capability performs many functions.

  1. Probability Distribution Function of Passive Scalars in Shell Models

    Institute of Scientific and Technical Information of China (English)

    LIU Chun-Ping; ZHANG Xiao-Qiang; LIU Yu-Rong; WANG Guang-Rui; HE Da-Ren; CHEN Shi-Gang; ZHU Lu-Jin

    2008-01-01

    A shell-model version of passive scalar problem is introduced, which is inspired by the model of K. Ohkitani and M. Yakhot [K. Ohkitani and M. Yakhot, Phys. Rev. Lett. 60 (1988) 983; K. Ohkitani and M. Yakhot, Prog. Theor. Phys. 81 (1988) 329]. As in the original problem, the prescribed random velocity field is Gaussian and 5 correlated in time. Deterministic differential equations are regarded as nonlinear Langevin equation. Then, the Fokker-Planck equations of PDF for passive scalars axe obtained and solved numerically. In energy input range (n < 5, n is the shell number.), the probability distribution function (PDF) of passive scalars is near the Gaussian distribution. In inertial range (5 < n < 16) and dissipation range (n ≥ 17), the probability distribution function (PDF) of passive scalars has obvious intermittence. And the scaling power of passive scalar is anomalous. The results of numerical simulations are compared with experimental measurements.

  2. Administrative Circulars No. 12 A (Rev. 2) - "Education fees” and No. 12 B (Rev. 2) - “Education fees and language courses”

    CERN Multimedia

    2013-01-01

    Administrative Circulars No. 12 A (Rev. 2) entitled “Education fees” and No. 12 B (Rev. 2) entitled “Education fees and language courses”, approved by the Director-General following discussion at the Standing Concertation Committee meeting of 27 June 2013 and entering into force on 1 August 2013, are available on the intranet site of the Human Resources Department (see here).   Administrative Circular No. 12 A (Rev. 2) is applicable to Staff Members (except former “Local Staff Members”) recruited before 1st January 2007. Administrative Circular No. 12 B (Rev. 2) is applicable to Staff Members recruited on or after 1st January 2007, to Fellows, to Scientific Associates, to Guest Professors and to former “Local Staff” recruited before 1st January 2007. They cancel and replace Administrative Circulars No. 12 A (Rev. 1/Corr.) entitled "Education fees” and No. 12 B (Rev. 1/Corr.) entitled “Edu...

  3. Sampling and estimation techniques for the implementation of new classification systems: the change-over from NACE Rev. 1.1 to NACE Rev. 2 in business surveys

    Directory of Open Access Journals (Sweden)

    Jan van den Brakel

    2010-09-01

    Full Text Available This paper describes some of the methodological problems encountered with the change-over from the NACE Rev. 1.1 to the NACE Rev. 2 in business statistics. Different sampling and estimation strategies are proposed to produce reliable figures for the domains under both classifications simultaneously. Furthermore several methods are described that can be used to reconstruct time series for the domains under the NACE Rev. 2.

  4. Quantum protocols within Spekkens' toy model

    Science.gov (United States)

    Disilvestro, Leonardo; Markham, Damian

    2017-05-01

    Quantum mechanics is known to provide significant improvements in information processing tasks when compared to classical models. These advantages range from computational speedups to security improvements. A key question is where these advantages come from. The toy model developed by Spekkens [R. W. Spekkens, Phys. Rev. A 75, 032110 (2007), 10.1103/PhysRevA.75.032110] mimics many of the features of quantum mechanics, such as entanglement and no cloning, regarded as being important in this regard, despite being a local hidden variable theory. In this work, we study several protocols within Spekkens' toy model where we see it can also mimic the advantages and limitations shown in the quantum case. We first provide explicit proofs for the impossibility of toy bit commitment and the existence of a toy error correction protocol and consequent k -threshold secret sharing. Then, defining a toy computational model based on the quantum one-way computer, we prove the existence of blind and verified protocols. Importantly, these two last quantum protocols are known to achieve a better-than-classical security. Our results suggest that such quantum improvements need not arise from any Bell-type nonlocality or contextuality, but rather as a consequence of steering correlations.

  5. Comment on ``Monte Carlo investigation of current voltage and avalanche noise in GaN double-drift impact diodes'' [J. Appl. Phys. 97, 043709 (2005)

    Science.gov (United States)

    Dash, G. N.

    2005-11-01

    The avalanche noise behavior of impact avalanche transit-time (IMPATT) diodes has been modeled by Reklaitis and Reggiani [J. Appl. Phys. 97, 043709 (2005)]. They have obtained general agreement of their results with those of McIntyre [IEEE Trans. Electron Devices ED-13, 164 (1966)]. However, McIntyre's theory predicts the opposite noise behavior from that observed in the IMPATT diode. Hence the applicability of the noise model of Reklaitis and Reggiani to IMPATT diode is questionable.

  6. RNA helicase MOV10 functions as a co-factor of HIV-1 Rev to facilitate Rev/RRE-dependent nuclear export of viral mRNAs

    Energy Technology Data Exchange (ETDEWEB)

    Huang, Feng; Zhang, Junsong; Zhang, Yijun; Geng, Guannan; Liang, Juanran; Li, Yingniang; Chen, Jingliang [Institute of Human Virology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080 (China); Key Laboratory of Tropical Disease Control of Ministry of Education, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080 (China); Liu, Chao, E-mail: liuchao9@mail.sysu.edu.cn [Institute of Human Virology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080 (China); Key Laboratory of Tropical Disease Control of Ministry of Education, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080 (China); Zhang, Hui [Institute of Human Virology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080 (China); Key Laboratory of Tropical Disease Control of Ministry of Education, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080 (China)

    2015-12-15

    Human immunodeficiency virus type 1 (HIV-1) exploits multiple host factors during its replication. The REV/RRE-dependent nuclear export of unspliced/partially spliced viral transcripts needs the assistance of host proteins. Recent studies have shown that MOV10 overexpression inhibited HIV-1 replication at various steps. However, the endogenous MOV10 was required in certain step(s) of HIV-1 replication. In this report, we found that MOV10 potently enhances the nuclear export of viral mRNAs and subsequently increases the expression of Gag protein and other late products through affecting the Rev/RRE axis. The co-immunoprecipitation analysis indicated that MOV10 interacts with Rev in an RNA-independent manner. The DEAG-box of MOV10 was required for the enhancement of Rev/RRE-dependent nuclear export and the DEAG-box mutant showed a dominant-negative activity. Our data propose that HIV-1 utilizes the anti-viral factor MOV10 to function as a co-factor of Rev and demonstrate the complicated effects of MOV10 on HIV-1 life cycle. - Highlights: • MOV10 can function as a co-factor of HIV-1 Rev. • MOV10 facilitates Rev/RRE-dependent transport of viral mRNAs. • MOV10 interacts with Rev in an RNA-independent manner. • The DEAG-box of MOV10 is required for the enhancement of Rev/RRE-dependent export.

  7. Theory of inclusive breakup cross section for Borromean nuclei within a four-body spectator model

    CERN Document Server

    Carlson, Brett V; Hussein, Mahir S

    2016-01-01

    We develop a model to treat the inclusive non-elastic break up reactions involving weakly bound three-cluster nuclei. Borromean, two-nucleon, halo nuclei are candidates of unstable three-fragments projectiles. The model is based on the theory of inclusive breakup reactions commonly employed in the treatment of incomplete fusion and surrogate method. The theory was developed in the 80's by Ichimura, Autern and Vincent (IAV) [Phys. Rev. C 32, 431 (1985)] \\cite{IAV1985}, Udagawa and Tamura (UT)[Phys. Rev. C 24, 1348 (1981)], \\cite{UT1981} and Hussein and McVoy (HM)[Nucl. Phys. A 445, 124 (1985)], \\cite{HM1985}. We extend these three-body theories to derive an expression for the fragment yield in the reaction $A\\,(a,b)\\,X$, where the projectile is $a = x_1 + x_2 + b$. The inclusive breakup cross section is found to be the sum of a generalized four-body form of the elastic breakup cross section plus the inclusive non-elastic breakup cross section which involves the "reaction" cross section of the participant fragm...

  8. Qudit quantum computation in the Jaynes-Cummings model

    DEFF Research Database (Denmark)

    Mischuck, Brian; Mølmer, Klaus

    2013-01-01

    We have developed methods for performing qudit quantum computation in the Jaynes-Cummings model with the qudits residing in a finite subspace of individual harmonic oscillator modes, resonantly coupled to a spin-1/2 system. The first method determines analytical control sequences for the one......- and two-qudit gates necessary for universal quantum computation by breaking down the desired unitary transformations into a series of state preparations implemented with the Law-Eberly scheme [ Law and Eberly Phys. Rev. Lett. 76 1055 (1996)]. The second method replaces some of the analytical pulse...

  9. Qudit quantum computation in the Jaynes-Cummings model

    DEFF Research Database (Denmark)

    Mischuck, Brian; Mølmer, Klaus

    2013-01-01

    We have developed methods for performing qudit quantum computation in the Jaynes-Cummings model with the qudits residing in a finite subspace of individual harmonic oscillator modes, resonantly coupled to a spin-1/2 system. The first method determines analytical control sequences for the one......- and two-qudit gates necessary for universal quantum computation by breaking down the desired unitary transformations into a series of state preparations implemented with the Law-Eberly scheme [ Law and Eberly Phys. Rev. Lett. 76 1055 (1996)]. The second method replaces some of the analytical pulse...

  10. Quantum chaos in the nuclear collective model. II. Peres lattices.

    Science.gov (United States)

    Stránský, Pavel; Hruska, Petr; Cejnar, Pavel

    2009-06-01

    This is a continuation of our paper [Phys. Rev. E 79, 046202 (2009)] devoted to signatures of quantum chaos in the geometric collective model of atomic nuclei. We apply the method by Peres to study ordered and disordered patterns in quantum spectra drawn as lattices in the plane of energy vs average of a chosen observable. Good qualitative agreement with standard measures of chaos is manifested. The method provides an efficient tool for studying structural changes in eigenstates across quantum spectra of general systems.

  11. Design of octahedral spherical hohlraum for CH Rev5 ignition capsule

    Science.gov (United States)

    Cao, Hui; Chen, Yao-Hua; Zhai, Chuanlei; Zheng, Chunyang; Lan, Ke

    2017-08-01

    In this paper, we design an octahedral spherical Au hohlraum for CH Rev5 ignition capsule [S. W. Haan et al., Phys. Plasmas 18, 051001 (2011)] by using the initial design method and two-dimensional (2D) simulations, and we investigate its laser entrance hole (LEH) closure and laser-plasma instabilities (LPI) by using a spherical hohlraum with two different-size LEHs via 2D simulations. The designed spherical hohlraum with RH=5 RC, RL=1.2 mm , and RL*=2 RL requires an ignition laser pulse of 1.92 MJ in energy and 670 TW in peak power, where RH, RC, RL, and RL* are radii of the spherical hohlraum, capsule, LEH, and the cylindrical LEH outer ring, respectively. From 2D simulations, the closure and opening up of LEH are clearly obtained. The LEH closure and its rate are strongly connected to the radiation pulse, while the LEH opening-up and its rate are strongly connected to the laser pulse. The smallest radius of LEH during closure is 0.6 mm before opening up, which leaves enough room for arranging the laser beams with a radius of 0.5 mm in our design. By using a post-process code for LPI, a relatively high stimulated Brillouin scattering fraction and a very low stimulated Raman scattering fraction are predicted, which may be due to the neglection of three-dimensional density gradients of the ablative flow along the laser transportation in 2D simulations. This work provides the energy and power references for the future ignition laser facility which uses octahedral spherical hohlraums as ignition targets.

  12. S-matrices and quantum group symmetry of k-deformed sigma models

    Science.gov (United States)

    Hollowood, Timothy J.; Miramontes, J. Luis; Schmidtt, David M.

    2016-11-01

    Recently, two kinds of integrable deformations of the string world sheet theory in the gauge/gravity correspondence have been constructed (Delduc et al 2014 Phys. Rev. Lett. 112 051601; Hollowood et al 2014 J. Phys. A: Math. Theor. 47 495402). One class of these, the k deformations associated to the more general q deformations but with q={{{e}}}{{i}π /k} a root of unity, has been shown to be related to a particular discrete deformation of the principal chiral models and (semi-)symmetric space sigma models involving a gauged WZW model. We conjecture a form for the exact S-matrices of the bosonic integrable field theories of this type. The S-matrices imply that the theories have a hidden infinite dimensional affine quantum group symmetry. We provide some evidence, via quantum inverse scattering techniques, that the theories do indeed possess the finite-dimensional part of this quantum group symmetry.

  13. 12MW Horns Rev experiment[Wind farm

    Energy Technology Data Exchange (ETDEWEB)

    Hasager, C.B.; Pena, A; Mikkelsen, T.; Courtney, M.; Antoniou, I.; Gryning, S.-E.; Hansen, P. [Risoe National Lab., DTU, Wind Energy Dept. (Denmark); Soerensen, P.B. [DONG Energy (Denmark)

    2007-10-15

    The 12MW project with the full title '12 MW wind turbines: the scientific basis for their operation at 70 to 270 m height offshore' has the goal to experimentally investigate the wind and turbulence characteristics between 70 and 270 m above sea level and thereby establish the scientific basis relevant for the next generation of huge 12 MW wind turbines operating offshore. The report describes the experimental campaign at the Horns Rev offshore wind farm at which observations from Doppler Laser LIDAR and SODAR were collected from 3 May to 24 October 2006. The challenges for mounting and operating the instruments on the transformer platform at Horns Rev were overcome by a close collaboration between DONG energy and Risoe National Laboratory DTU. The site is presented. In particular, three tall offshore meteorological masts, up to 70 m tall, provided a useful source of meteorological data for comparison to the remotely sensed wind and turbulence observations. The comparison showed high correlation. The LIDAR and SODAR wind and turbulence observations were collected far beyond the height of the masts (up to 160 m above sea level) and the extended profiles were compared to the logarithmic wind profile. Further studies on this part of the work are on-going. Technical detail on LIDAR and SODAR are provided as well as theoretical work on turbulence and atmospheric boundary layer flow. Selected results from the experimental campaign are reported. (au)

  14. Comparative analysis of Rev function in human immunodeficiency virus types 1 and 2.

    OpenAIRE

    Garrett, E D; Cullen, B R

    1992-01-01

    The Rev proteins of the related but distinct human immunodeficiency virus types 1 and 2 (HIV-1 and HIV-2) display incomplete functional reciprocity. One possible explanation for this observation is that HIV-2 Rev is unable to interact with the HIV-1 Rev-response element (RRE1). However, an analysis of the biological activity of chimeric proteins derived from HIV-1 and HIV-2 Rev reveals that this target specificity does not map to the Rev RNA binding domain but is instead primarily determined ...

  15. Phase-field modeling of binary alloy solidification with coupled heat and solute diffusion.

    Science.gov (United States)

    Ramirez, J C; Beckermann, C; Karma, A; Diepers, H-J

    2004-05-01

    A phase-field model is developed for simulating quantitatively microstructural pattern formation in solidification of dilute binary alloys with coupled heat and solute diffusion. The model reduces to the sharp-interface equations in a computationally tractable thin-interface limit where (i). the width of the diffuse interface is about one order of magnitude smaller than the radius of curvature of the interface but much larger than the real microscopic width of a solid-liquid interface, and (ii). kinetic effects are negligible. A recently derived antitrapping current [Phys. Rev. Lett. 87, 115701 (2001)

  16. Nonlinear Acoustic Landmine Detection: Profiling Soil Surface Vibrations and Modeling Mesoscopic Elastic Behavior

    Science.gov (United States)

    2007-05-04

    amplitude of oscillation, 01 0, kF ox <<−=− and A kF ox <<−=+ 02 , , where 12 kk < . If 02 =k , the elastoplastic case of Iwan’s model for...curve identifies the system as potentially mesoscopic elastic. The elasto-slip model of elastoplastic hysteresis presented by Iwan exhibits linear...in damaged concrete: Quantitative analysis of slow and fast dynamics,” Phys. Rev. B, 73, 014116 (2006). Bolton, M.D., and Wilson, J.M.R, “An

  17. Dissipative structures in an optomechanical cavity model with a microstructured oscillating end mirror

    CERN Document Server

    Ruiz-Rivas, J; Roldán, Eugenio; de Valcárcel, Germán J

    2016-01-01

    We theoretically consider the possibility of generating nonlinear transverse patterns in an optomechanical system in which the mechanical element is a microstructured oscillating end-mirrror consisting in an array of weakly-coupled micromirrors. While in the limit of large number of micro-mirrors we naturally recover the continuous model that we recently studied in [Ruiz-Rivas et al., Phys. Rev. A 93, 033850 (2015)], we pay special numerical attention to the opposite limit, showing that the structures predicted with the continuous model can be observed for a number of micro-mirrors as low as ten or less. This opens new venues for experimental approaches to the subject.

  18. Alternative model of the Antonov problem: Generalization with the presence of a mass spectrum

    Science.gov (United States)

    Velazquez, L.; García, S. Gómez; Guzmán, F.

    2009-01-01

    We extend the quasiergodic model proposed as an alternative version of the Antonov isothermal model [L. Velazquez and F. Guzman, Phys. Rev. E 68, 066116 (2003)] by including the incidence of a mass spectrum. We propose an iterative procedure inspired by the Newton-Raphson method to solve the resulting nonlinear structure equations. As an example of application, we assume the existence of a mass spectrum with a standard Salpeter form, dN=Cdm/mα . We analyze consequences of this realistic ingredient on the system thermodynamical behavior and perform a quantitative description of the mass segregation effect.

  19. Kinetic exchange opinion model: solution in the single parameter map limit

    CERN Document Server

    Chowdhury, Krishanu Roy; Biswas, Soumyajyoti; Chakrabarti, Bikas K

    2011-01-01

    We study a recently proposed kinetic exchange opinion model (Lallouache et. al., Phys. Rev E 82, 056112 (2010)) in the limit of a single parameter map. Although it does not include the essentially complex behavior of the multiagent version, it provides us with the insight regarding the choice of order parameter for the system as well as some of its other dynamical properties. We also study the generalized two-parameter version of the model, and provide the exact phase diagram. The universal behavior along this phase boundary in terms of the suitably defined order parameter is seen.

  20. Publication Of Administrative Circulars: No. 4 (Rev. 4) – Unemployment Insurance Scheme No. 30 (Rev. 2) – Financial Benefits on Taking Up Appointment and on Termination of Contract

    CERN Multimedia

    HR Department

    2008-01-01

    Administrative Circular No. 4 (Rev. 4) – Unemployment insurance scheme Administrative Circular No. 4 (Rev. 4) – "Unemployment insurance scheme", approved following discussion at the Standing Concertation Committee meetings of 28 August 2007 and 27 February 2008, is now available on the intranet site of the Human Resources Department. It cancels and replaces Administrative Circular No. 4 (Rev. 3) – "Unemployment insurance" of October 1993. Copies will shortly be available in Departmental secretariats. Human Resources Department Tel. 78003 Administrative Circular No. 30 (Rev. 2) – Financial benefits on taking up appointment and termination of contract Administrative Circular No. 30 (Rev. 2) – "Financial benefits on taking up appointment and termination of contract", approved following discussion at the Standing Concertation Committee meetings of 28 August 2007 and 27 February 2008, is now available on the intranet site of the Human Resources De...

  1. Publication Of Administrative Circulars: No. 4 (Rev. 4) – Unemployment Insurance Scheme No. 30 (Rev. 2) – Financial Benefits on Taking Up Appointment and on Termination of Contract

    CERN Multimedia

    HR Department

    2008-01-01

    Administrative Circular No. 4 (Rev. 4) – Unemployment insurance scheme Administrative Circular No. 4 (Rev. 4) – "Unemployment insurance scheme", approved following discussion in the Standing Concertation Committee meetings of 28 August 2007 and 27 February 2008, is now available on the intranet site of the Human Resources Department. It cancels and replaces Administrative Circular No. 4 (Rev. 3) – "Unemployment insurance" of October 1993. Copies will shortly be available in Departmental secretariats. Human Resources Department Tel. 78003 Administrative Circular No. 30 (Rev. 2) – Financial benefits on taking up appointment and termination of contract Administrative Circular No. 30 (Rev. 2) – "Financial benefits on taking up appointment and termination of contract", approved following discussion in the Standing Concertation Committee meetings of 28 August 2007 and 27 February 2008, is now available on the intranet site of the Human Resources De...

  2. Tight-Binding and Hueckel Models of Molecular Clusters

    Science.gov (United States)

    1990-05-01

    Chem. Phys. Lett. 163, 323 (1989); Phys. Rev. Lett. 64, 551 (1990). 16. H. Kupka and K. Jug, Chem. Phys. 130, 23 (1989). 17. Y. Wang , T. F. George...D. M. Lindsay and A. C. Beri, J. Chem. Phys. 86, 3493 (1987). 18. D. M. Lindsay, Y. Wang and T. F. George, J. Chem. Phys. 86, 3500 (1987). 23 Table 1...Department of Chemistry Northwestern University University of California Evanston, IL 60208 Irvine, CA 92717 Professor Frank DiSalvo Professor Roald Hoffmann

  3. Mean-field modeling of thalamocortical dynamics and a model-driven approach to EEG analysis.

    Science.gov (United States)

    Victor, Jonathan D; Drover, Jonathan D; Conte, Mary M; Schiff, Nicholas D

    2011-09-13

    Higher brain function depends on task-dependent information flow between cortical regions. Converging lines of evidence suggest that interactions between cortical regions and the central thalamus play a key role in establishing the dynamic patterns of functional connectivity that normally support these processes. In patients with chronic disturbances of cognitive function due to severe brain injury, dysfunction of this circuitry likely plays a crucial role in pathogenesis. However, assaying thalamocortical interactions is challenging even in healthy subjects and more so in severely impaired patients. To approach this problem, we apply a dynamical-systems approach to motivate an analysis of the electroencephalogram (EEG). We begin with a model for a single thalamocortical module [Robinson PA, Rennie CJ, Rowe DL (2002) Phys Rev E Stat Nonlin Soft Matter Phys 65:041924; Robinson PA, Rennie CJ, Wright JJ, Bourke PD (1998) Phys Rev E Stat Nonlin Soft Matter Phys 58:3557-3571]. When two such modules interact via shared thalamic inhibition, multistable behavior emerges; each mode is characterized by a different pattern of coherence between cortical regions. This observation suggests that changing patterns of cortical coherence are a hallmark of normal thalamocortical dynamics. In a preliminary study, we test this idea by analyzing the EEG of a patient with chronic brain injury, who has a marked improvement in behavior and frontal brain metabolism in response to zolpidem. The analysis shows that following zolpidem administration, changing patterns of coherence are identified between the frontal lobes and between frontal and distant brain regions. These observations support the role of the central thalamus in the organization of patterns of cortical interactions and suggest how indexes of thalamocortical dynamics can be extracted from the EEG.

  4. Design and Implementation of 3D Dressing System Based on Physics Engine PhysX%基于物理引擎PhysX的3D试衣系统的设计与实现

    Institute of Scientific and Technical Information of China (English)

    徐康熙; 郝泳涛

    2014-01-01

    In order to achieve the 3D fitting function and solve the problem of large algorithm time complexity of virtual try modeling, based on virtual reality technology, this paper tend to model clothing fabric by sprint-mass model. Then, based on Newton's second law, we analysis the spring-mass model-based forces of clothing fabric modeling. Combined with GPU-based physics engine PhysX, build the 3D fitting room, simulate the sports interactive situation of fabrics and mannequin. Finally add mannequin adjustment, the election of clothing, dressing and other functions. Built under Windows platform, designed and devel-oped by using VisualStudio2008, combined with the comprehensive application of virtual reality technology, we establish the 3D fitting system, including functions such as clothing select, dressing, body parameter adjustment .%为了实现3D试衣功能及解决虚拟试衣建模算法时间复杂度比较大的问题,该文结合虚拟现实等技术,首先用弹簧-质点模型对服装布料进行建模,然后以牛顿第二定律为理论基础分析以质点-弹簧模型建模的服装布料的受力情况,结合以GPU为基础的物理引擎PhysX,建立3D试衣间,仿真服装布料与人体模型的运动交互状况。最后加入人体模型调整、选衣、试衣等功能。该系统在Windows平台下,利用VisualStudio2008设计开发,结合虚拟现实等技术的综合应用,建立了一套包括选衣、试衣、人体参数调整等功能的3D试衣系统。

  5. Geology of outer Horns Rev, Danish North Sea

    Energy Technology Data Exchange (ETDEWEB)

    Jensen, Joern B.; Gravesen, P.; Lomholt, S. (Geological Survey of Denmark and Greenland, Copenhagen (Denmark))

    2008-07-15

    In 2006, Dong Energy initiated the development of the Horns Rev II offshore wind farm in the North Sea. In order to evaluate and map the characteristics of the surface features of the sea bed and to characterise the subsurface in the wind farm area, the Geological Survey of Denmark and Greenland (GEUS) conducted a geophysical survey of the area. The survey utilised a variety of instruments: sparker, side-scan sonar, marine caesium magnetometer and a multibeam echo-sounder. In addition, information on the subsurface sediments was obtained by cone penetration tests (CPT) and by drilling to 30-50 m below the sea bottom. Geological correlation of the CPT results with the other survey results was extremely complicated but was required in order to understand the architecture of the ice marginal glaciotectonic complex. Information on the geology is crucial for evaluation of the geotechnical problems of the region. (au)

  6. Self-truncation and scaling in Euler-Voigt-α and related fluid models.

    Science.gov (United States)

    Di Molfetta, Giuseppe; Krstlulovic, Giorgio; Brachet, Marc

    2015-07-01

    A generalization of the 3D Euler-Voigt-α model is obtained by introducing derivatives of arbitrary order β (instead of 2) in the Helmholtz operator. The β→∞ limit is shown to correspond to Galerkin truncation of the Euler equation. Direct numerical simulations (DNS) of the model are performed with resolutions up to 2048(3) and Taylor-Green initial data. DNS performed at large β demonstrate that this simple classical hydrodynamical model presents a self-truncation behavior, similar to that previously observed for the Gross-Pitaeveskii equation in Krstulovic and Brachet [Phys. Rev. Lett. 106, 115303 (2011)]. The self-truncation regime of the generalized model is shown to reproduce the behavior of the truncated Euler equation demonstrated in Cichowlas et al. [Phys. Rev. Lett. 95, 264502 (2005)]. The long-time growth of the self-truncation wave number k(st) appears to be self-similar. Two related α-Voigt versions of the eddy-damped quasinormal Markovian model and the Leith model are introduced. These simplified theoretical models are shown to reasonably reproduce intermediate time DNS results. The values of the self-similar exponents of these models are found analytically.

  7. On the relation between Vicsek and Kuramoto models of spontaneous synchronization

    Science.gov (United States)

    Chepizhko, A. A.; Kulinskii, V. L.

    2010-12-01

    The Vicsek model for self-propelling particles in 2D is investigated with respect to the addition of the stochastic perturbation of dynamic equations. We show that this model represents in essence the same type of bifurcations under a different type of noise as the celebrated Kuramoto model of spontaneous synchronization. These models demonstrate similar behavior at least within the mean-field approach. To prove this we consider two types of noise for the Vicsek model which are commonly considered in the literature: the intrinsic and the extrinsic ones (according to the terminology of Pimentel et al. [J.A. Pimentel, M. Aldana, C. Huepe, H. Larralde, Intrinsic and extrinsic noise effects on phase transitions of network models with applications to swarming systems, Physical Review E: Statistical, Nonlinear, and Soft Matter Physics 77 (6) (2008) doi:10.1103/PhysRevE.77.061138. URL: http://dx.doi.org/10.1103/PhysRevE.77.061138]). The qualitative correspondence with the bifurcation of stationary states in the Kuramoto model is stated. A new type of stochastic perturbation-the “mixed” noise is proposed. It is constructed as the weighted superposition of the intrinsic and the extrinsic noises. The corresponding phase diagram “noise amplitude vs. interaction strength” is obtained. The possibility of the tricritical behavior for the Vicsek model is predicted.

  8. Configurational entropy as a bounding of Gauss-Bonnet braneworld models

    CERN Document Server

    Correa, R A C; Dutra, A de Souza; de Paula, W; Frederico, T

    2016-01-01

    Configurational entropy has been revealed as a reliable method for constraining some parameters of a given model [Phys. Rev. D \\textbf{92} (2015) 126005, Eur. Phys. J. C \\textbf{76} (2016) 100]. In this letter we calculate the configurational entropy in Gauss-Bonnet braneworld models. Our results restrict the range of acceptability of the Gauss-Bonnet scalar values. In this way, the information theoretical measure in Gauss-Bonnet scenarios opens a new window to probe situations where the additional parameters, responsible for the Gauss-Bonnet sector, are arbitrary. We also show that such an approach is very important in applications that include p and Dp-branes and various superstring-motivated theories.

  9. Delay time embedding of mass loss avalanches in a fusion plasma-oriented sandpile model

    Science.gov (United States)

    Bowie, C. A.; Dendy, R. O.; Hole, M. J.

    2016-10-01

    The sandpile paradigm is widely used to model aspects of the phenomenology of magnetically confined fusion (MCF) plasmas, including enhanced confinement, edge pedestals and, potentially, the impulsive energy and particle release process known as ELMing. Here we identify new points of contact between ELMing and the systemwide avalanches in a sandpile. We compare the quantified response [Calderon et al., Phys. Plasmas 20, 042306 (2014)] to increased fuelling of the time sequence of edge localised mode events in a series of similar Joint European Torus plasmas with the response to increased fuelling of the time sequence of systemwide avalanches in a sandpile model [Chapman et al., Phys. Rev. Lett. 86, 2814 (2001)] that has well established links to MCF plasma phenomenology. Both the probability density functions of inter-event time intervals, and delay time embeddings of event time sequences, at different fuelling rates, show common features and point to shared underlying physics.

  10. Human REV3 DNA Polymerase Zeta Localizes to Mitochondria and Protects the Mitochondrial Genome.

    Science.gov (United States)

    Singh, Bhupendra; Li, Xiurong; Owens, Kjerstin M; Vanniarajan, Ayyasamy; Liang, Ping; Singh, Keshav K

    2015-01-01

    To date, mitochondrial DNA polymerase γ (POLG) is the only polymerase known to be present in mammalian mitochondria. A dogma in the mitochondria field is that there is no other polymerase present in the mitochondria of mammalian cells. Here we demonstrate localization of REV3 DNA polymerase in the mammalian mitochondria. We demonstrate localization of REV3 in the mitochondria of mammalian tissue as well as cell lines. REV3 associates with POLG and mitochondrial DNA and protects the mitochondrial genome from DNA damage. Inactivation of Rev3 leads to reduced mitochondrial membrane potential, reduced OXPHOS activity, and increased glucose consumption. Conversely, inhibition of the OXPHOS increases expression of Rev3. Rev3 expression is increased in human primary breast tumors and breast cancer cell lines. Inactivation of Rev3 decreases cell migration and invasion, and localization of Rev3 in mitochondria increases survival and the invasive potential of cancer cells. Taken together, we demonstrate that REV3 functions in mammalian mitochondria and that mitochondrial REV3 is associated with the tumorigenic potential of cells.

  11. RNA-guided assembly of Rev-RRE nuclear export complexes.

    Science.gov (United States)

    Bai, Yun; Tambe, Akshay; Zhou, Kaihong; Doudna, Jennifer A

    2014-08-27

    HIV replication requires nuclear export of unspliced and singly spliced viral transcripts. Although a unique RNA structure has been proposed for the Rev-response element (RRE) responsible for viral mRNA export, how it recruits multiple HIV Rev proteins to form an export complex has been unclear. We show here that initial binding of Rev to the RRE triggers RNA tertiary structural changes, enabling further Rev binding and the rapid formation of a viral export complex. Analysis of the Rev-RRE assembly pathway using SHAPE-Seq and small-angle X-ray scattering (SAXS) reveals two major steps of Rev-RRE complex formation, beginning with rapid Rev binding to a pre-organized region presenting multiple Rev binding sites. This step induces long-range remodeling of the RNA to expose a cryptic Rev binding site, enabling rapid assembly of additional Rev proteins into the RNA export complex. This kinetic pathway may help maintain the balance between viral replication and maturation.DOI: http://dx.doi.org/10.7554/eLife.03656.001.

  12. REV3L modulates cisplatin sensitivity of non-small cell lung cancer H1299 cells.

    Science.gov (United States)

    Wang, Wenjie; Sheng, Wenjiong; Yu, Chenxiao; Cao, Jianping; Zhou, Jundong; Wu, Jinchang; Zhang, Huojun; Zhang, Shuyu

    2015-09-01

    Lung cancer remains the leading cause of cancer-related mortality worldwide and non-small cell lung cancer (NSCLC) accounts for approximately 80-85% of all cases of lung cancer. Cisplatin plays a significant role in the management of human lung cancer. Translesion DNA synthesis (TLS) is involved in DNA damage repair. DNA polymerase ζ (Pol ζ) is able to mediate the DNA replication bypass of DNA damage, which is suggested to be involved in chemoresistance. REV3L is the catalytic subunit of Pol ζ. Due to its critical role in translesion DNA synthesis, whether REV3L modulates cisplatin response in NSCLC cells remains unknown. In this study, REV3L overexpression and silencing H1299 cell lines were established. The reports showed that cisplatin induced the expression of REV3L by recruiting Sp1 to its promoter. Similar results were obtained when the ability of the cells to express luciferase from a platinated plasmid was measured. Co-transfection of the reporter with the REV3L overexpression vector or REV3L plus REV7L significantly enhanced the reporter activity. Nuclear condensation and fragmentation of shRNA-REV3L H1299 cells were more pronounced than shRNA-NC H1299 cells after cisplatin exposure, indicating that REV3L overexpression abolished cisplatin-induced DNA damage. Moreover, a forced expression of REV3L conferred the resistance of H1299 cells to cisplatin, whereas the knockdown of REV3L sensitized cisplatin efficacy in H1299 cells. Taken together, we demonstrated that inhibition of REV3L sensitized lung cancer H1299 cells to cisplatin treatment. Thus, REV3L may be a novel target for the chemotherapy of NSCLC.

  13. Contact angles in the pseudopotential lattice Boltzmann modeling of wetting

    Science.gov (United States)

    Li, Qing; Luo, K. H.; Kang, Q. J.; Chen, Q.

    2014-11-01

    In this paper we investigate the implementation of contact angles in the pseudopotential lattice Boltzmann modeling of wetting at a large density ratio ρL/ρV=500 . The pseudopotential lattice Boltzmann model [X. Shan and H. Chen, Phys. Rev. E 49, 2941 (1994), 10.1103/PhysRevE.49.2941] is a popular mesoscopic model for simulating multiphase flows and interfacial dynamics. In this model the contact angle is usually realized by a fluid-solid interaction. Two widely used fluid-solid interactions, the density-based interaction and the pseudopotential-based interaction, as well as a modified pseudopotential-based interaction formulated in the present paper are numerically investigated and compared in terms of the achievable contact angles, the maximum and the minimum densities, and the spurious currents. It is found that the pseudopotential-based interaction works well for simulating small static (liquid) contact angles θ static contact angles close to 180∘. Meanwhile, it is found that the proposed modified pseudopotential-based interaction performs better in light of the maximum and the minimum densities and is overall more suitable for simulating large contact angles θ >90∘ as compared with the two other types of fluid-solid interactions. Furthermore, the spurious currents are found to be enlarged when the fluid-solid interaction force is introduced. Increasing the kinematic viscosity ratio between the vapor and liquid phases is shown to be capable of reducing the spurious currents caused by the fluid-solid interactions.

  14. Global phase diagram of a doped Kitaev-Heisenberg model

    Energy Technology Data Exchange (ETDEWEB)

    Okamoto, Satoshi [ORNL

    2013-01-01

    The global phase diagram of a doped Kitaev-Heisenberg model is studied using an $SU(2)$ slave-boson mean-field method. Near the Kitaev limit, $p$-wave superconducting states which break the time-reversal symmetry are stabilized as reported by You {\\it et al.} [Phys. Rev. B {\\bf 86}, 085145 (2012)] irrespective of the sign of the Kitaev interaction. By further doping, a $d$-wave superconducting state appears when the Kitaev interaction is antiferromagnetic, while another $p$-wave superconducting state appears when the Kitaev interaction is ferromagnetic. This $p$-wave superconducting state does not break the time-reversal symmetry as reported by Hyart {\\it et al.} [Phys. Rev. B {\\bf 85}, 140510 (2012)], and such a superconducting state also appears when the antiferromagnetic Kitaev interaction and the ferromagnetic Heisenberg interaction compete. This work, thus, demonstrates the clear difference between the antiferromagnetic Kitaev model and the ferromagnetic Kitaev model when carriers are doped while these models are equivalent in the undoped limit, and how novel superconducting states emerge when the Kitaev interaction and the Heisenberg interaction compete.

  15. Comment on the paper Photoionization of endohedral atoms using R-matrix methods: application to Xe@C60 by T. W. Gorczyca, M. F. Hasoglu and S. T. Manson, Phys. Rev. A86, 033204 (2012) [1

    CERN Document Server

    Amusia, M Ya

    2013-01-01

    We demonstrate serious misrepresentation of existing experimental data and important omissions in the List of references in the paper [1]. We demonstrate that what is called in [1] total photoionization cross-section is in fact a partial photoionization cross-section. We demonstrate that long before [1] and presented there experimental data for photoionization of Xe@C60+ were obtained, a theoretical prediction for Xe@C60 have been published that was in a reasonable agreement with experiment. These data are even not mentioned in [1].

  16. Comment on the numerical measurements of the magnetohydrodynamic turbulence spectrum by A. Beresnyak (Phys. Rev. Lett. 106 (2011) 075001; MNRAS 422 (2012) 3495; ApJ 784 (2014) L20)

    CERN Document Server

    Perez, J C; Boldyrev, S; Cattaneo, F

    2014-01-01

    The inertial-interval energy spectrum of strong magnetohydrodynamic (MHD) turbulence with a uniform background magnetic field was observed numerically to be close to $k^{-3/2}$ by a number of independent groups. A dissenting opinion has been voiced by Beresnyak, A. 2011, PRL, 106, 075001-. 2012, MNRAS, 422, 3495-. 2014, ApJ, 784, L20 that the spectral scaling is close to $k^{-5/3}$. The conclusions of these papers are however incorrect as they are based on numerical simulations that are drastically unresolved, so that the discrete numerical scheme does not approximate the physical solution at the scales where the measurements are performed. These results have been rebutted in our more detailed papers Perez, J. C., Mason, J., Boldyrev, S., & Cattaneo, F. 2012, PRX, 2, 041005-. 2014, ApJL, 793, L13; here, by popular demand, we present a brief and simple explanation of our major criticism of Beresnyak's work.

  17. Ensemble-based forecasting at Horns Rev: Ensemble conversion and kernel dressing

    DEFF Research Database (Denmark)

    Pinson, Pierre; Madsen, Henrik

    methodology. In a first stage, ensemble forecasts of meteorological variables are converted to power through a suitable power curve model. The relevance and benefits of employing a newly developed orthogonal fitting method for the power curve model over the traditional least-squares one are discussed...... predictive distributions. Such a methodology has the benefit of yielding predictive distributions that are of increased reliability (in a probabilistic sense) in comparison with the raw ensemble forecasts, while taking advantage of their high resolution....... of probabilistic forecasts, the resolution of which may be maximized by using meteorological ensemble predictions as input. The paper concentrates on the test case of the Horns Rev wind farm over a period of approximately one year, in order to describe, apply and discuss a complete ensemble-based forecasting...

  18. Quasi-coherent fluctuations limiting the pedestal growth on Alcator C-Mod: Experiment and modelling

    Energy Technology Data Exchange (ETDEWEB)

    Diallo, A. [Princeton Plasma Physics Lab. (PPPL), Princeton, NJ (United States); Hughes, J. W. [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States); Baek, S. -G. [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States); LaBombard, Brian [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States); Terry, J. [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States); Cziegler, I. [Univ. of California, San Diego, CA (United States); Hubbard, A. [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States); Davis, E. [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States); Walk, J. [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States); Delgado-Aparicio, L. [Princeton Plasma Physics Lab. (PPPL), Princeton, NJ (United States); Reinke, M. L. [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States); Theiler, C. [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States); Churchhill, R. M. [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States); Edlund, E. M. [Princeton Plasma Physics Lab. (PPPL), Princeton, NJ (United States); Canik, John [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Snyder, P. [General Atomics, San Diego, CA (United States); Greenwald, M. [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States); White, A. [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States)

    2015-04-09

    Performance predictions for future fusion devices rely on an accurate model of the pedestal structure. The candidate for predictive pedestal structure is EPED, and it is imperative to test the underlying hypotheses to further gain confidence for ITER projections. Here, we present experimental work testing one of the EPED hypotheses, namely the existence of a soft limit set by microinstabilities such as the kinetic ballooning mode. Furthermore, this work extends recent work on Alactor C-Mod (Diallo et al 2014 Phys. Rev. Lett. 112 115001), to include detailed measurements of the edge fluctuations and comparisons of edge simulation codes and experimental observations.

  19. Cooperative Effects of Noise and Coupling on Stochastic Dynamics of a Membrane-Bulk Coupling Model

    Institute of Scientific and Technical Information of China (English)

    TANG Jun; JIA Ya; YI Ming

    2009-01-01

    Based on a membrane-bulk coupling cell model proposed by Gomez-Marin et al. [ Phys. Rev. Lett. 98 (2007) 168303], the cooperative effects of noise and coupling on the stochastic dynamical behavior are investigated, For parameters in a certain region, the oscillation can be induced by the cooperative effect of noise and coupling. Whether considering the coupling or not, corresponding coherence resonance phenomena are observed. Furthermore, the effects of two coupling parameters, cell size L and coupling intensity k, on the noise-induced oscillation of membranes are studied. Contrary effects of noise are found in and out of the deterministic oscillatory regions.

  20. GENERAL: Considering Backward Effect in Coupled Map Car-Following Model

    Science.gov (United States)

    Yu, Han-Mei; Cheng, Rong-Jun; Ge, Hong-Xia

    2010-07-01

    Based on the pioneer work of Konishi et al., a new control method is proposed to suppress the traffic congestion in the coupled map (CM) car-following model under open boundary condition. The influence of the following car to the system has been considered. Our method and that presented by Konishi et al. [Phys. Rev. E 60 (1999) 4000] are compared. Although both the methods could suppress the traffic jam, the simulation results show that the temporal behavior obtained by ours is better than that proposed by the Konishi's et al. The simulation results are consistent with the theoretical analysis.

  1. Finite size scaling and first-order phase transition in a modified XY model

    Science.gov (United States)

    Sinha, Suman; Roy, Soumen Kumar

    2010-02-01

    Monte Carlo simulation has been performed in a two-dimensional modified XY -model first proposed by Domany [Phys. Rev. Lett. 52, 1535 (1984)] The cluster algorithm of Wolff has been used and multiple histogram reweighting is performed. The first-order scaling behavior of the quantities such as specific heat and free-energy barrier are found to be obeyed accurately. While the lowest-order correlation function was found to decay to zero at long distance just above the transition, the next-higher-order correlation function shows a nonzero plateau.

  2. Parameterized post-Newtonian approximation in a teleparallel model of dark energy with a boundary term

    Energy Technology Data Exchange (ETDEWEB)

    Sadjadi, H.M. [University of Tehran, Department of Physics, Tehran (Iran, Islamic Republic of)

    2017-03-15

    We study the parameterized post-Newtonian approximation in teleparallel model of gravity with a scalar field. The scalar field is non-minimally coupled to the scalar torsion as well as to the boundary term introduced in Bahamonde and Wright (Phys Rev D 92:084034 arXiv:1508.06580v4 [gr-qc], 2015). We show that, in contrast to the case where the scalar field is only coupled to the scalar torsion, the presence of the new coupling affects the parameterized post-Newtonian parameters. These parameters for different situations are obtained and discussed. (orig.)

  3. Infinite-degree-corrected stochastic block model

    DEFF Research Database (Denmark)

    Herlau, Tue; Schmidt, Mikkel Nørgaard; Mørup, Morten

    2014-01-01

    In stochastic block models, which are among the most prominent statistical models for cluster analysis of complex networks, clusters are defined as groups of nodes with statistically similar link probabilities within and between groups. A recent extension by Karrer and Newman [Karrer and Newman......, Phys. Rev. E 83, 016107 (2011)] incorporates a node degree correction to model degree heterogeneity within each group. Although this demonstrably leads to better performance on several networks, it is not obvious whether modeling node degree is always appropriate or necessary. We formulate the degree...... corrected stochastic block model as a nonparametric Bayesian model, incorporating a parameter to control the amount of degree correction that can then be inferred from data. Additionally, our formulation yields principled ways of inferring the number of groups as well as predicting missing links...

  4. One-Particle-Thick, Solvent-Free, Coarse-Grained Model for Biological and Biomimetic Fluid Membranes

    Science.gov (United States)

    2010-07-01

    52 H. Strey and M. Peterson, Biophys. J. 69, 478 1995. 53 T. Auth, S. A. Safran , and N. S. Gov, Phys. Rev. E 76, 051910 2007. 54 Y. Park...S. A. Safran , Phys. Rev. A 36, 4371 1987. 57 H. Yuan, C. Huang, and S. Zhang, Soft Matter to be pub- lished. YUAN et al. PHYSICAL REVIEW E 82, 011905 2010 011905-8

  5. Publication of administrative circular No. 26 (Rev. 8) – Recognition of merit

    CERN Multimedia

    HR Department

    2008-01-01

    Administrative Circular No. 26 (Rev. 8) – Recognition of merit Administrative Circular No. 26 (Rev. 8) – "Recognition of merit", approved by the Standing Concertation Committee at its meeting on 3 September 2008, is now available on the intranet site of the Human Resources Department. It cancels and replaces Administrative Circular No. 26 (Rev. 7) – "Recognition of merit of staff members" of May 2007. Paper copies will shortly be available in Departmental secretariats. Human Resources Department Tel. 78003

  6. Publication of administrative circular No. 26 (Rev. 8) – Recognition of merit

    CERN Multimedia

    HR Department

    2008-01-01

    Administrative Circular No. 26 (Rev. 8) – Recognition of merit Administrative Circular No. 26 (Rev. 8) – "Recognition of merit", approved by the Standing Concertation Committee meeting on 3 September 2008, is now available on the intranet site of the Human Resources Department. It cancels and replaces Administrative Circular No. 26 (Rev. 7) – "Recognition of merit of staff members" of May 2007. Paper copies will shortly be available in Departmental secretariats. Human Resources Department Tel. 78003

  7. Suured fondid on varunud börsile mineva Teede REV-2 aktsiaid / Annika Matson

    Index Scriptorium Estoniae

    Matson, Annika, 1976-

    2004-01-01

    Seoses Teede REV-2 aktsionäride kavaga aktsiate noteerimiseks Tallinna börsil 2005. aasta alguses, on Hansa Balti Kasvufond, Sampo Uus Euroopa Fond ja Ühispanga Kasvufond ostnud hallatavatesse investeerimisportfellidesse ehitusettevõtte aktsiaid. Diagrammid: Suure osa Teede REV-2 aktsiate omanikest tegevjuhid; Teede-Rev 2 ootab tänavu käibe kasvu. Kommenteerib Aivaras Abromavicius

  8. Totally Asymmetric Limit for Models of Heat Conduction

    Science.gov (United States)

    De Carlo, Leonardo; Gabrielli, Davide

    2017-08-01

    We consider one dimensional weakly asymmetric boundary driven models of heat conduction. In the cases of a constant diffusion coefficient and of a quadratic mobility we compute the quasi-potential that is a non local functional obtained by the solution of a variational problem. This is done using the dynamic variational approach of the macroscopic fluctuation theory (Bertini et al. in Rev Mod Phys 87:593, 2015). The case of a concave mobility corresponds essentially to the exclusion model that has been discussed in Bertini et al. (J Stat Mech L11001, 2010; Pure Appl Math 64(5):649-696, 2011; Commun Math Phys 289(1):311-334, 2009) and Enaud and Derrida (J Stat Phys 114:537-562, 2004). We consider here the convex case that includes for example the Kipnis-Marchioro-Presutti (KMP) model and its dual (KMPd) (Kipnis et al. in J Stat Phys 27:6574, 1982). This extends to the weakly asymmetric regime the computations in Bertini et al. (J Stat Phys 121(5/6):843-885, 2005). We consider then, both microscopically and macroscopically, the limit of large externalfields. Microscopically we discuss some possible totally asymmetric limits of the KMP model. In one case the totally asymmetric dynamics has a product invariant measure. Another possible limit dynamics has instead a non trivial invariant measure for which we give a duality representation. Macroscopically we show that the quasi-potentials of KMP and KMPd, which are non local for any value of the external field, become local in the limit. Moreover the dependence on one of the external reservoirs disappears. For models having strictly positive quadratic mobilities we obtain instead in the limit a non local functional having a structure similar to the one of the boundary driven asymmetric exclusion process.

  9. Heterogeneous out-of-equilibrium nonlinear q -voter model with zealotry

    Science.gov (United States)

    Mellor, Andrew; Mobilia, Mauro; Zia, R. K. P.

    2017-01-01

    We study the dynamics of the out-of-equilibrium nonlinear q -voter model with two types of susceptible voters and zealots, introduced in Mellor et al. [Europhys. Lett. 113, 48001 (2016), 10.1209/0295-5075/113/48001]. In this model, each individual supports one of two parties and is either a susceptible voter of type q1 or q2, or is an inflexible zealot. At each time step, a qi-susceptible voter (i =1 ,2 ) consults a group of qi neighbors and adopts their opinion if all group members agree, while zealots are inflexible and never change their opinion. This model violates detailed balance whenever q1≠q2 and is characterized by two distinct regimes of low and high density of zealotry. Here, by combining analytical and numerical methods, we investigate the nonequilibrium stationary state of the system in terms of its probability distribution, nonvanishing currents, and unequal-time two-point correlation functions. We also study the switching time properties of the model by exploiting an approximate mapping onto the model of Mobilia [Phys. Rev. E 92, 012803 (2015), 10.1103/PhysRevE.92.012803] that satisfies the detailed balance, and we outline some properties of the model near criticality.

  10. Impact of blood rheology on wall shear stress in a model of the middle cerebral artery

    Science.gov (United States)

    Bernabeu, Miguel O.; Nash, Rupert W.; Groen, Derek; Carver, Hywel B.; Hetherington, James; Krüger, Timm; Coveney, Peter V.

    2013-01-01

    Perturbations to the homeostatic distribution of mechanical forces exerted by blood on the endothelial layer have been correlated with vascular pathologies, including intracranial aneurysms and atherosclerosis. Recent computational work suggests that, in order to correctly characterize such forces, the shear-thinning properties of blood must be taken into account. To the best of our knowledge, these findings have never been compared against experimentally observed pathological thresholds. In this work, we apply the three-band diagram (TBD) analysis due to Gizzi et al. (Gizzi et al. 2011 Three-band decomposition analysis of wall shear stress in pulsatile flows. Phys. Rev. E 83, 031902. (doi:10.1103/PhysRevE.83.031902)) to assess the impact of the choice of blood rheology model on a computational model of the right middle cerebral artery. Our results show that, in the model under study, the differences between the wall shear stress predicted by a Newtonian model and the well-known Carreau–Yasuda generalized Newtonian model are only significant if the vascular pathology under study is associated with a pathological threshold in the range 0.94–1.56 Pa, where the results of the TBD analysis of the rheology models considered differs. Otherwise, we observe no significant differences. PMID:24427534

  11. Solvable continuous-time random walk model of the motion of tracer particles through porous media.

    Science.gov (United States)

    Fouxon, Itzhak; Holzner, Markus

    2016-08-01

    We consider the continuous-time random walk (CTRW) model of tracer motion in porous medium flows based on the experimentally determined distributions of pore velocity and pore size reported by Holzner et al. [M. Holzner et al., Phys. Rev. E 92, 013015 (2015)PLEEE81539-375510.1103/PhysRevE.92.013015]. The particle's passing through one channel is modeled as one step of the walk. The step (channel) length is random and the walker's velocity at consecutive steps of the walk is conserved with finite probability, mimicking that at the turning point there could be no abrupt change of velocity. We provide the Laplace transform of the characteristic function of the walker's position and reductions for different cases of independence of the CTRW's step duration τ, length l, and velocity v. We solve our model with independent l and v. The model incorporates different forms of the tail of the probability density of small velocities that vary with the model parameter α. Depending on that parameter, all types of anomalous diffusion can hold, from super- to subdiffusion. In a finite interval of α, ballistic behavior with logarithmic corrections holds, which was observed in a previously introduced CTRW model with independent l and τ. Universality of tracer diffusion in the porous medium is considered.

  12. DDX5 facilitates HIV-1 replication as a cellular co-factor of Rev.

    Directory of Open Access Journals (Sweden)

    Xiuxia Zhou

    Full Text Available HIV-1 Rev plays an important role in the late phase of HIV-1 replication, which facilitates export of unspliced viral mRNAs from the nucleus to cytoplasm in infected cells. Recent studies have shown that DDX1 and DDX3 are co-factors of Rev for the export of HIV-1 transcripts. In this report, we have demonstrated that DDX5 (p68, which is a multifunctional DEAD-box RNA helicase, functions as a new cellular co-factor of HIV-1 Rev. We found that DDX5 affects Rev function through the Rev-RRE axis and subsequently enhances HIV-1 replication. Confocal microscopy and co-immunoprecipitation analysis indicated that DDX5 binds to Rev and this interaction is largely dependent on RNA. If the DEAD-box motif of DDX5 is mutated, DDX5 loses almost all of its ability to bind to Rev, indicating that the DEAD-box motif of DDX5 is required for the interaction between DDX5 and Rev. Our data indicate that interference of DDX5-Rev interaction could reduce HIV-1 replication and potentially provide a new molecular target for anti-HIV-1 therapeutics.

  13. Identification of the first small-molecule inhibitor of the REV7 DNA repair protein interaction.

    Science.gov (United States)

    Actis, Marcelo L; Ambaye, Nigus D; Evison, Benjamin J; Shao, Youming; Vanarotti, Murugendra; Inoue, Akira; McDonald, Ezelle T; Kikuchi, Sotaro; Heath, Richard; Hara, Kodai; Hashimoto, Hiroshi; Fujii, Naoaki

    2016-09-15

    DNA interstrand crosslink (ICL) repair (ICLR) has been implicated in the resistance of cancer cells to ICL-inducing chemotherapeutic agents. Despite the clinical significance of ICL-inducing chemotherapy, few studies have focused on developing small-molecule inhibitors for ICLR. The mammalian DNA polymerase ζ, which comprises the catalytic subunit REV3L and the non-catalytic subunit REV7, is essential for ICLR. To identify small-molecule compounds that are mechanistically capable of inhibiting ICLR by targeting REV7, high-throughput screening and structure-activity relationship (SAR) analysis were performed. Compound 1 was identified as an inhibitor of the interaction of REV7 with the REV7-binding sequence of REV3L. Compound 7 (an optimized analog of compound 1) bound directly to REV7 in nuclear magnetic resonance analyses, and inhibited the reactivation of a reporter plasmid containing an ICL in between the promoter and reporter regions. The normalized clonogenic survival of HeLa cells treated with cisplatin and compound 7 was lower than that for cells treated with cisplatin only. These findings indicate that a small-molecule inhibitor of the REV7/REV3L interaction can chemosensitize cells by inhibiting ICLR.

  14. Comment on ``Multicritical behavior of a square-lattice-gas model with anisotropic repulsive interactions: A transfer-matrix scaling study''

    Science.gov (United States)

    Caflisch, Robert G.

    1988-09-01

    An argument is given that the model of Buda, Florio, and Giaquinta (BFG)[Phys. Rev. B 35, 2021 (1987)] for anisotropic molecules on a square lattice is inappropriate in that context, because it confuses anisotropy of the lattice with the anisotropy of the molecule. The importance of this is made clear by noting the absence (in BFG) of a dilute isotropic phase. Such a phase is unavoidable on very general grounds. Comments are made about an alternative realization of their results and an alternative class of models for anisotropic molecules.

  15. Generalized hard-core dimer model approach to low-energy Heisenberg frustrated antiferromagnets: General properties and application to the kagome antiferromagnet

    Science.gov (United States)

    Schwandt, David; Mambrini, Matthieu; Poilblanc, Didier

    2010-06-01

    We propose a general nonperturbative scheme that quantitatively maps the low-energy sector of spin-1/2 frustrated Heisenberg antiferromagnets to effective generalized quantum dimer models. We develop the formal lattice-independent frame and establish some important results on (i) the locality of the generated Hamiltonians, (ii) how full resummations can be performed in this renormalization scheme. The method is then applied to the much debated kagome antiferromagnet for which a fully resummed effective Hamiltonian—shown to capture the essential properties and provide deep insights on the microscopic model [D. Poilblanc, M. Mambrini, and D. Schwandt, Phys. Rev. B 81, 180402(R) (2010)]—is derived.

  16. Comment on ``Minimum free-energy pathway of nucleation'' [J. Chem. Phys. 135, 134508 (2011)

    Science.gov (United States)

    Schmelzer, Jürn W. P.; Abyzov, Alexander S.

    2012-03-01

    In their recent paper [J. Chem. Phys. 135, 134508 (2011)], Philippe and Blavette, 10.1063/1.3644935 claimed to have found for the first time—based on minimum free energy considerations—that the nucleation pathway in solid solutions involves a universal two-step behavior: nuclei sharply enrich up to near equilibrium values of the concentration and then grow. This claim of priority is not correct. The same scenario was proposed by us long ago [J. W. P. Schmelzer, A. R. Gokhman, and V. M. Fokin, J. Colloid Interface Sci. 272, 109 (2004)], 10.1016/j.jcis.2003.08.038 and then applied and further developed. In particular, it was shown by us that only the account of both thermodynamic and kinetic factors allows one to determine correctly the most probable path of evolution in nucleation-growth processes. The two-step scenario is retained, however, also in these generalizations of our original approach.

  17. Comment on "Deterministic six states protocol for quantum communication" [Phys. Lett. A 358 (2006) 85

    CERN Document Server

    El-Orany, Faisal A A

    2011-01-01

    In [J.S. Shaari, M. Lucamarini, M.R.B. Wahiddin, Phys. Lett. A 358 (2006) 85-90] the deterministic six states protocol (6DP) for quantum communication has been developed. This protocol is based on three mutually unbiased bases and four encoding operators. Information is transmitted between the users via two qubits from different bases. Three attacks have been studied; namely intercept-resend attack (IRA), double-CNOT attack (2CNOTA) and quantum man-in-the-middle attack. In this Letter, we show that the IRA and 2CNOTA are not properly addressed. For instance, we show that the probability of detecting Eve in the control mode of the IRA is 70% instead of 50% in the previous study. Moreover, in the 2CNOTA, Eve can only obtain 50% of the data not all of it as argued earlier.

  18. Comment on “Effects of damping solitary wave in a viscosity bounded plasma” [Phys. Plasmas 21, 022118 (2014)

    Energy Technology Data Exchange (ETDEWEB)

    Ghosh, Uday Narayan, E-mail: unghosh1@rediffmail.com; Chatterjee, Prasanta; Roychoudhury, Rajkumar [Department of Mathematics, Siksha Bhavana, Visva Bharati, Santiniketan 731235 (India)

    2015-07-15

    Recently Gun Li et al. discussed “Effects of damping solitary wave in a viscosity bounded plasma” [Phys. Plasmas 21, 022118 (2014)]. The paper contains some serious errors which have been pointed out in this Comment.

  19. Wind Farm Wake: The Horns Rev Photo Case

    Directory of Open Access Journals (Sweden)

    Pierre-Elouan Réthoré

    2013-02-01

    Full Text Available The aim of the paper is to examine the nowadays well-known wind farm wake photographs taken on 12 February 2008 at the offshore Horns Rev 1 wind farm. The meteorological conditions are described from observations from several satellite sensors quantifying clouds, surface wind vectors and sea surface temperature as well as ground-based information at and near the wind farm, including Supervisory Control and Data Acquisition (SCADA data. The SCADA data reveal that the case of fog formation occurred 12 February 2008 on the 10:10 UTC. The fog formation is due to very special atmospheric conditions where a layer of cold humid air above a warmer sea surface re-condensates to fog in the wake of the turbines. The process is fed by warm humid air up-drafted from below in the counter-rotating swirl generated by the clock-wise rotating rotors. The condensation appears to take place primarily in the wake regions with relatively high axial velocities and high turbulent kinetic energy. The wind speed is near cut-in and most turbines produce very little power. The rotational pattern of spiraling bands produces the large-scale structure of the wake fog.

  20. Subtlety in the Critical Behavior of the Two Dimensional XY Model

    Science.gov (United States)

    Kim, Jae-Kwon

    1996-03-01

    We study the two dimensional classical XY model using the single cluster Monte Carlo algorithm^1. We present extensive high -temperature -phase bulk data that are extracted based on a novel finite- size- scaling Monte Carlo technique^2. The largest value of the estimated bulk correlation length is 1390 in lattice units. Our data reveal that η=1/4 sets in near criticality. The standard finite-size-scaling analysis of the data close to criticality, however, seems to indicate that η=1/4 is compatible only for a critical temperature (T_c) over the range 0.900 Wolff, Phys. Rev. Lett. 62, 361 (1989) ^2 J.-K. Kim, Euro. Phys. Lett. 28, 211 (1994) Research supported in part by the NSF

  1. A study on entanglement dynamics for a four-qubit model

    Institute of Scientific and Technical Information of China (English)

    Man Zhong-Xiao; Xia Yun-Jie

    2008-01-01

    In this paper,we consider the entanglement dynamics of a four-qubit model[2006 Phys.Rev.A 74 042328]where two entangled qubits a and b locally interact with separate qubits A and B via the spin-exchange-like Hamiltonian.We study the effect of purity of initial entangled state of qubits a,b on the entanglement evolution and its relation with energy transfer.Also,we find that the total bipartite entanglement of qubits a,b plus A,B is not a constant any longer when the initial entangled state of a,b is not pure,which is a complement to the result in the paper[2007 J.Phys.B 40 S45] for the pure case.

  2. Collaborative Research and Development. Delivery Order 0006: Transmission Electron Microscope Image Modeling and Semiconductor Heterointerface Characterization

    Science.gov (United States)

    2006-09-01

    J. Harper, M. Weimer, C. -H. Lin, and S. S. Pei, Phys. Rev. Lett. 85, 4562 (2000) and references therein. 27. J. L. Rouviere and N. Bonnet, Inst...Phys. Conf. Ser. 134, 11 (1993). 28. J. F. Aebersold, P. A. Stadelman, and J. L. Rouviere , Ultramicroscopy 62, 171 (1996). 29. P. Trebbia

  3. Intrinsic and extrinsic noise effects on phase transitions of network models with applications to swarming systems.

    Science.gov (United States)

    Pimentel, Jaime A; Aldana, Maximino; Huepe, Cristián; Larralde, Hernán

    2008-06-01

    We analyze order-disorder phase transitions driven by noise that occur in two kinds of network models closely related to the self-propelled model proposed by Vicsek [Phys. Rev. Lett. 75, 1226 (1995)] to describe the collective motion of groups of organisms. Two different types of noise, which we call intrinsic and extrinsic, are considered. The intrinsic noise, the one used by Vicsek in their original work, is related to the decision mechanism through which the particles update their positions. In contrast, the extrinsic noise, later introduced by Grégoire and Chaté [Phys. Rev. Lett. 92, 025702 (2004)], affects the signal that the particles receive from the environment. The network models presented here can be considered as mean-field representations of the self-propelled model. We show analytically and numerically that, for these two network models, the phase transitions driven by the intrinsic noise are continuous, whereas the extrinsic noise produces discontinuous phase transitions. This is true even for the small-world topology, which induces strong spatial correlations between the network elements. We also analyze the case where both types of noise are present simultaneously. In this situation, the phase transition can be continuous or discontinuous depending upon the amplitude of each type of noise.

  4. H-rev107 Regulates Cytochrome P450 Reductase Activity and Increases Lipid Accumulation.

    Directory of Open Access Journals (Sweden)

    Fu-Ming Tsai

    Full Text Available H-rev107 is a member of the HREV107 type II tumor suppressor gene family and acts as a phospholipase to catalyze the release of fatty acids from glycerophospholipid. H-rev107 has been shown to play an important role in fat metabolism in adipocytes through the PGE2/cAMP pathway, but the detailed molecular mechanism underlying H-rev107-mediated lipid degradation has not been studied. In this study, the interaction between H-rev107 and cytochrome P450 reductase (POR, which is involved in hepatic lipid content regulation, was determined by yeast two-hybrid screen and confirmed by using in vitro pull down assays and immunofluorescent staining. The expression of POR in H-rev107-expressing cells enhanced the H-rev107-mediated release of arachidonic acid. However, H-rev107 inhibited POR activity and relieved POR-mediated decreased triglyceride content in HtTA and HeLa cervical cells. The inhibitory effect of H-rev107 will be abolished when POR-expressing cells transfected with PLA2-lacking pH-rev107 or treated with PLA2 inhibitor. Silencing of H-rev107 using siRNA resulted in increased glycerol production and reversion of free fatty acid-mediated growth suppression in Huh7 hepatic cells. In summary, our results revealed that H-rev107 is also involved in lipid accumulation in liver cells through the POR pathway via its PLA2 activity.

  5. Characterizing 3-qubit UPB states: violations of LHV models, preparation via nonlocal unitaries and PPT entangled nonlocal orbits

    CERN Document Server

    Altafini, C

    2004-01-01

    For the 3-qubit UPB state, i.e., the bound entangled state constructed from an Unextendable Product Basis of Bennett et al. (Phys. Rev. Lett. 82:5385, 1999), we provide a set of violations of Local Hidden Variable (LHV) models based on the particular type of reflection symmetry encoded in this state. The explicit nonlocal unitary operation needed to prepare the state from its reflected separable mixture of pure states is given, as well as a nonlocal one-parameter orbit of states with Positive Partial Transpositions (PPT) which swaps the entanglement between a state and its reflection twice during a period.

  6. Fluctuation theorems for discrete kinetic models of molecular motors

    Science.gov (United States)

    Faggionato, Alessandra; Silvestri, Vittoria

    2017-04-01

    Motivated by discrete kinetic models for non-cooperative molecular motors on periodic tracks, we consider random walks (also not Markov) on quasi one dimensional (1d) lattices, obtained by gluing several copies of a fundamental graph in a linear fashion. We show that, for a suitable class of quasi-1d lattices, the large deviation rate function associated to the position of the walker satisfies a Gallavotti-Cohen symmetry for any choice of the dynamical parameters defining the stochastic walk. This class includes the linear model considered in Lacoste et al (2008 Phys. Rev. E 78 011915). We also derive fluctuation theorems for the time-integrated cycle currents and discuss how the matrix approach of Lacoste et al (2008 Phys. Rev. E 78 011915) can be extended to derive the above Gallavotti-Cohen symmetry for any Markov random walk on {Z} with periodic jump rates. Finally, we review in the present context some large deviation results of Faggionato and Silvestri (2017 Ann. Inst. Henri Poincaré 53 46-78) and give some specific examples with explicit computations.

  7. Compressibility enhancement in an almost staggered interacting Harper model

    Science.gov (United States)

    Friedman, Bat-el; Berkovits, Richard

    2015-03-01

    We discuss the compressibility in the almost staggered fermionic Harper model with repulsive interactions in the vicinity of half-filling. It has been shown by Kraus et al. [Phys. Rev. B 89, 161106(R) (2014)], 10.1103/PhysRevB.89.161106 that for spinless electrons and nearest neighbors electron-electron interactions the compressibility in the central band is enhanced by repulsive interactions. Here we would like to investigate the sensitivity of this conclusion to the spin degree of freedom and longer range interactions. We use the Hartree-Fock (HF) approximation, as well as the density matrix renormalization group (DMRG) calculation to evaluate the compressibility. In the almost staggered Harper model, the central energy band is essentially flat and separated from the other bands by a large gap and therefore, the HF approximation is rather accurate. In both cases the compressibility of the system is enhanced compared to the noninteracting case, although the enhancement is weaker due to the inclusion of Hubbard and longer ranged interactions. We also show that the entanglement entropy is suppressed when the compressibility of the system is enhanced.

  8. Multilevel selection in a resource-based model

    Science.gov (United States)

    Ferreira, Fernando Fagundes; Campos, Paulo R. A.

    2013-07-01

    In the present work we investigate the emergence of cooperation in a multilevel selection model that assumes limiting resources. Following the work by R. J. Requejo and J. Camacho [Phys. Rev. Lett.0031-900710.1103/PhysRevLett.108.038701 108, 038701 (2012)], the interaction among individuals is initially ruled by a prisoner's dilemma (PD) game. The payoff matrix may change, influenced by the resource availability, and hence may also evolve to a non-PD game. Furthermore, one assumes that the population is divided into groups, whose local dynamics is driven by the payoff matrix, whereas an intergroup competition results from the nonuniformity of the growth rate of groups. We study the probability that a single cooperator can invade and establish in a population initially dominated by defectors. Cooperation is strongly favored when group sizes are small. We observe the existence of a critical group size beyond which cooperation becomes counterselected. Although the critical size depends on the parameters of the model, it is seen that a saturation value for the critical group size is achieved. The results conform to the thought that the evolutionary history of life repeatedly involved transitions from smaller selective units to larger selective units.

  9. Modeling squeezing and thermal disorder in driven oscillators

    CERN Document Server

    Sewran, Sashwin; Sergi, Alessandro

    2014-01-01

    Recently, model systems with quadratic Hamiltonians and time-dependent interactions were studied by Briegel and Popescu and by Galve et al in order to consider the possibility of both quantum refrigeration in enzymes [Proc. R. Soc. 469, 20110290 (2013)] and entanglement in the high temperature limit [Phys. Rev. Lett. 105, 180501 (2010); Phys. Rev. A 81, 062117 (2010)]. Following this line of research, we studied a model comprising two quantum harmonic oscillators driven by a time-dependent harmonic coupling. Such a system was embedded in a thermal bath represented in two different ways. In one case, the bath was composed of a finite but great number of independent harmonic oscillators with an Ohmic spectral density. In the other case, the bath was more efficiently defined in terms of a single oscillator coupled to a non-Hamiltonian thermostat. In both cases, we simulated the effect of the thermal disorder on the generation of the squeezed states in the two-oscillators relevant system. We found that, in our mo...

  10. Langevin model for reactive transport in porous media

    Science.gov (United States)

    Tartakovsky, Alexandre M.

    2010-08-01

    Existing continuum models for reactive transport in porous media tend to overestimate the extent of solute mixing and mixing-controlled reactions because the continuum models treat both the mechanical and diffusive mixings as an effective Fickian process. Recently, we have proposed a phenomenological Langevin model for flow and transport in porous media [A. M. Tartakovsky, D. M. Tartakovsky, and P. Meakin, Phys. Rev. Lett. 101, 044502 (2008)10.1103/PhysRevLett.101.044502]. In the Langevin model, the fluid flow in a porous continuum is governed by a combination of a Langevin equation and a continuity equation. Pore-scale velocity fluctuations, the source of mechanical dispersion, are represented by the white noise. The advective velocity (the solution of the Langevin flow equation) causes the mechanical dispersion of a solute. Molecular diffusion and sub-pore-scale Taylor-type dispersion are modeled by an effective stochastic advection-diffusion equation. Here, we propose a method for parameterization of the model for a synthetic porous medium, and we use the model to simulate multicomponent reactive transport in the porous medium. The detailed comparison of the results of the Langevin model with pore-scale and continuum (Darcy) simulations shows that: (1) for a wide range of Peclet numbers the Langevin model predicts the mass of reaction product more accurately than the Darcy model; (2) for small Peclet numbers predictions of both the Langevin and the Darcy models agree well with a prediction of the pore-scale model; and (3) the accuracy of the Langevin and Darcy model deteriorates with the increasing Peclet number but the accuracy of the Langevin model decreases more slowly than the accuracy of the Darcy model. These results show that the separate treatment of advective and diffusive mixing in the stochastic transport model is more accurate than the classical advection-dispersion theory, which uses a single effective diffusion coefficient (the dispersion

  11. Biological Characterization of CVRM2-BAC, A Recombinant CV1988 Virus Containing an REV LTR Insertion

    Science.gov (United States)

    It has been previously reported that avian retroviruses, i.e. avian leukosis virus (ALV) and reticoloendotheliosis virus (REV), integrate in the Marek’s disease virus genome affecting MDV pathogenicity. RM-2 is an attenuated serotype 1 MDV virus generated by insertion of the REV LTR in the genome of...

  12. 48 CFR 53.301-18 - SF 18 (Rev. 6/95), Request for Quotations.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false SF 18 (Rev. 6/95), Request for Quotations. 53.301-18 Section 53.301-18 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION (CONTINUED) CLAUSES AND FORMS FORMS Illustrations of Forms 53.301-18 SF 18 (Rev. 6/95),...

  13. 48 CFR 53.301-1414 - SF 1414 (Rev. 10/93) Consent of Surety.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false SF 1414 (Rev. 10/93) Consent of Surety. 53.301-1414 Section 53.301-1414 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION (CONTINUED) CLAUSES AND FORMS FORMS Illustrations of Forms 53.301-1414 SF 1414 (Rev....

  14. Protective efficacy of a recombinant BAC clone of Marek's disease virus containing REV-LTR

    Science.gov (United States)

    Insertion of reticuloendotheliosis virus (REV) long-terminal repeat (LTR) into a bacterial artificial chromosome (BAC) clone of a very virulent strain of Marek’s disease (MD) virus (MDV), Md5 (Kim et al, 2011) rendered the resultant recombinant virus termed rMd5 REV-LTR BAC fully attenuated at passa...

  15. Pharmacological and Genetic Modulation of REV-ERB Activity and Expression Affects Orexigenic Gene Expression.

    Directory of Open Access Journals (Sweden)

    Ariadna Amador

    Full Text Available The nuclear receptors REV-ERBα and REV-ERBβ are transcription factors that play pivotal roles in the regulation of the circadian rhythm and various metabolic processes. The circadian rhythm is an endogenous mechanism, which generates entrainable biological changes that follow a 24-hour period. It regulates a number of physiological processes, including sleep/wakeful cycles and feeding behaviors. We recently demonstrated that REV-ERB-specific small molecules affect sleep and anxiety. The orexinergic system also plays a significant role in mammalian physiology and behavior, including the regulation of sleep and food intake. Importantly, orexin genes are expressed in a circadian manner. Given these overlaps in function and circadian expression, we wanted to determine whether the REV-ERBs might regulate orexin. We found that acute in vivo modulation of REV-ERB activity, with the REV-ERB-specific synthetic ligand SR9009, affects the circadian expression of orexinergic genes in mice. Long term dosing with SR9009 also suppresses orexinergic gene expression in mice. Finally, REV-ERBβ-deficient mice present with increased orexinergic transcripts. These data suggest that the REV-ERBs may be involved in the repression of orexinergic gene expression.

  16. PREFACE: International Symposium "Nanoscience and Quantum Physics 2011" (nanoPHYS'11)

    Science.gov (United States)

    Saito, Susumu; Tanaka, Hidekazu; Nakamura, Takashi; Nakamura, Masaaki

    2011-07-01

    Quantum physics has developed modern views of nature for more than a century. In addition to this traditional role, quantum physics has acquired new significance in the 21st century as the field responsible for driving and supporting nanoscience research, which will have even greater importance in the future because nanoscience will be the academic foundation for new technologies. The Department of Physics, Tokyo Institute of Technology, are now conducting a "Nanoscience and Quantum Physics" project (Physics G-COE project) supported by the Global Center of Excellence Program of the Ministry of Education, Culture, Sports, Science and Technology of Japan (MEXT) in order to promote research and education in these important academic fields. The International Symposium on Nanoscience and Quantum Physics, held in Tokyo, Japan, 26-28 January 2011 (nanoPHYS'11) was organized by the Physics G-COE project of the Tokyo Institute of Technology to provide an international forum for the open exchange of topical information and for stimulating discussion on novel concepts and future prospects of nanoscience and quantum physics. There were a total of 118 papers including 34 invited papers. This nanoPHYS'11 is the fourth symposium of this kind organized by the Tokyo Institute of Technology. Topics focused on in the symposium included: Category 1: Novel nanostructure (Nanowires, Nanotubes, Spin-related structure, etc) Category 2: Novel transport and electronic properties (Graphene, Topological insulators, Coherent control, etc) Category 3: Electronic and optical properties of nanostructure Category 4: Fundamental physics and new concept in quantum physics Category 5: Quantum Physics - Quantum information Category 6: Quantum Physics - Nuclear and Hadron Physics Category 7: Quantum Physics - Astrophysics, etc All the papers submitted to this issue have been reviewed under a stringent refereeing process, according to the normal rules of this Journal. The editors are grateful to all the

  17. Nuclear receptor REV-ERBα mediates circadian sensitivity to mortality in murine vesicular stomatitis virus-induced encephalitis.

    Science.gov (United States)

    Gagnidze, Khatuna; Hajdarovic, Kaitlyn H; Moskalenko, Marina; Karatsoreos, Ilia N; McEwen, Bruce S; Bulloch, Karen

    2016-05-17

    Certain components and functions of the immune system, most notably cytokine production and immune cell migration, are under circadian regulation. Such regulation suggests that circadian rhythms may have an effect on disease onset, progression, and resolution. In the vesicular stomatitis virus (VSV)-induced encephalitis model, the replication, caudal penetration, and survivability of intranasally applied VSV depends on both innate and adaptive immune mechanisms. In the current study, we investigated the effect of circadian time of infection on the progression and outcome of VSV-induced encephalitis and demonstrated a significant decrease in the survival rate in mice infected at the start of the rest cycle, zeitgeber time 0 (ZT0). The lower survival rate in these mice was associated with higher levels of circulating chemokine (C-C motif) ligand 2 (CCL2), a greater number of peripherally derived immune cells accumulating in the olfactory bulb (OB), and increased production of proinflammatory cytokines, indicating an immune-mediated pathology. We also found that the acrophase of molecular circadian clock component REV-ERBα mRNA expression in the OB coincides with the start of the active cycle, ZT12, when VSV infection results in a more favorable outcome. This result led us to hypothesize that REV-ERBα may mediate the circadian effect on survival following VSV infection. Blocking REV-ERBα activity before VSV administration resulted in a significant increase in the expression of CCL2 and decreased survival in mice infected at the start of the active cycle. These data demonstrate that REV-ERBα-mediated inhibition of CCL2 expression during viral-induced encephalitis may have a protective effect.

  18. HIV-1 pre-mRNA commitment to Rev mediated export through PSF and Matrin 3

    Energy Technology Data Exchange (ETDEWEB)

    Kula, Anna; Gharu, Lavina [The Laboratory of Molecular Virology, International Centre for Genetic Engineering and Biotechnology (ICGEB), Padriciano 99, 34012 Trieste (Italy); Marcello, Alessandro, E-mail: marcello@icgeb.org [The Laboratory of Molecular Virology, International Centre for Genetic Engineering and Biotechnology (ICGEB), Padriciano 99, 34012 Trieste (Italy)

    2013-01-20

    Human immunodeficiency virus gene expression and replication are regulated at several levels. Incompletely spliced viral RNAs and full-length genomic RNA contain the RRE element and are bound by the viral trans-acting protein Rev to be transported out of the nucleus. Previously we found that the nuclear matrix protein MATR3 was a cofactor of Rev-mediated RNA export. Here we show that the pleiotropic protein PSF binds viral RNA and is associated with MATR3. PSF is involved in the maintenance of a pool of RNA available for Rev activity. However, while Rev and PSF bind the viral pre-mRNA at the site of viral transcription, MATR3 interacts at a subsequent step. We propose that PSF and MATR3 define a novel pathway for RRE-containing HIV-1 RNAs that is hijacked by the viral Rev protein.

  19. Entropic lattice Boltzmann model for gas dynamics: Theory, boundary conditions, and implementation.

    Science.gov (United States)

    Frapolli, N; Chikatamarla, S S; Karlin, I V

    2016-06-01

    We present in detail the recently introduced entropic lattice Boltzmann model for compressible flows [N. Frapolli et al., Phys. Rev. E 92, 061301(R) (2015)PLEEE81539-375510.1103/PhysRevE.92.061301]. The model is capable of simulating a wide range of laminar and turbulent flows, from thermal and weakly compressible flows to transonic and supersonic flows. The theory behind the construction of the model is laid out and its thermohydrodynamic limit is discussed. Based on this theory and the hydrodynamic limit thereof, we also construct the boundary conditions necessary for the simulation of solid walls. We present the inlet and outlet boundary conditions as well as no-slip and free-slip boundary conditions. Details necessary for the implementation of the compressible lattice Boltzmann model are also reported. Finally, simulations of compressible flows are presented, including two-dimensional supersonic and transonic flows around a diamond and a NACA airfoil, the simulation of the Schardin problem, and the three-dimensional simulation of the supersonic flow around a conical geometry.

  20. c-Myc-miR-29c-REV3L signalling pathway drives the acquisition of temozolomide resistance in glioblastoma.

    Science.gov (United States)

    Luo, Hui; Chen, Zhengxin; Wang, Shuai; Zhang, Rui; Qiu, Wenjin; Zhao, Lin; Peng, Chenghao; Xu, Ran; Chen, Wanghao; Wang, Hong-Wei; Chen, Yuanyuan; Yang, Jingmin; Zhang, Xiaotian; Zhang, Shuyu; Chen, Dan; Wu, Wenting; Zhao, Chunsheng; Cheng, Gang; Jiang, Tao; Lu, Daru; You, Yongping; Liu, Ning; Wang, Huibo

    2015-12-01

    Resistance to temozolomide poses a major clinical challenge in glioblastoma multiforme treatment, and the mechanisms underlying the development of temozolomide resistance remain poorly understood. Enhanced DNA repair and mutagenesis can allow tumour cells to survive, contributing to resistance and tumour recurrence. Here, using recurrent temozolomide-refractory glioblastoma specimens, temozolomide-resistant cells, and resistant-xenograft models, we report that loss of miR-29c via c-Myc drives the acquisition of temozolomide resistance through enhancement of REV3L-mediated DNA repair and mutagenesis in glioblastoma. Importantly, disruption of c-Myc/miR-29c/REV3L signalling may have dual anticancer effects, sensitizing the resistant tumours to therapy as well as preventing the emergence of acquired temozolomide resistance. Our findings suggest a rationale for targeting the c-Myc/miR-29c/REV3L signalling pathway as a promising therapeutic approach for glioblastoma, even in recurrent, treatment-refractory settings.

  1. Effect of nacelle on the wake meandering in Horns Rev wind farm

    Science.gov (United States)

    Yang, Xiaolei; Foti, Daniel; Sotiropoulos, Fotis

    2016-11-01

    Turbine wake meandering has considerable effects on the velocity deficit and turbulence intensity in the wake. However, the mechanism for wake meandering is still not well understood and low-order models cannot take into account the wake meandering effects accurately. A recent work by Kang, Yang and Sotiropoulos showed that the nacelle has a significant effect on the wake meandering of a hydrokinetic turbine. To examine the nacelle contributions to wake meandering and wake interactions in utility-scale wind farms, we simulate the atmospheric turbulent flow over the Horns Rev wind farm using large-eddy simulation with actuator type models. In a preliminary simulation on a coarse grid using actuator line model for turbine blades without a nacelle model, the computed power shows overall good agreement with field measurements. Fine grid simulations using an actuator surface model for turbine blades with and without a nacelle model are being carried out. The corresponding results will be presented with analysis on wake meandering dynamics using the technique proposed by Horward et al. and Foti et al.. This work was supported by DOE (DE-AC04-94AL85000), Xcel Energy (Grant RD4-13) and Sandia National Laboratories. Computational resources were provided by National Renewable Energy Laboratory and University of Minnesota Supercomputing Institute.

  2. Bayesian Assessment of Accuracy Properties of Rose Bengal Test in REV-1 Vaccinated Small Ruminants

    Directory of Open Access Journals (Sweden)

    KUJTIM MERSINAJ

    2015-12-01

    Full Text Available The live Brucella melitensis Rev-1 strain is considered the best vaccine available for the prevention of brucellosis in small ruminants. In Albania, vaccination of small ruminants with REV-1 has been used under various regimes since 2004. The effectiveness of the vaccination campaigns is monitored through a post vaccination monitoring and surveillance system based on testing vaccinated animals with Rose Bengal Plate Test (RBPT. Regrettably the test accuracy properties such as the sensitivity and specificity have not been validated in vaccinated small ruminants. The lack of knowledge on these properties hampers the correct evaluation of the true sero-conversion rate of the post vaccination monitoring at national and at flock scale. This study addressed this issue by using a Bayesian modelling framework to estimate two serological tests the RBPT which is the standard serological test used in the post vaccination monitoring and Complement Fixation Test (CFT. Serum samples from 191 reportedly vaccinated small ruminants were tested in parallel with RBPT and CFT. The estimates of sensitivity and specificity values of RBPT were 91% (95% CrI: 82 -98 and 89% (95% CrI: 70 - 98. For CFT the sensitivity resulted 86% (95% CrI: 70 - 95 and the specificity 95% (95% CrI: 80 - 99. The good sensitivity and acceptable specificity of RBPT support its utilization as screening test for post vaccination monitoring. The interpretation of the post vaccination data with RBPT are well acceptable at national level but not well suited for flock status interpretation. In terms of disease diagnosis, especially for a latter phase of the brucellosis control strategy in Albania, both tests could justify their use in association.

  3. PyDecay/GraphPhys: A Unified Language and Storage System for Particle Decay Process Descriptions

    Energy Technology Data Exchange (ETDEWEB)

    Dunietz, Jesse N.; /MIT /SLAC

    2011-06-22

    To ease the tasks of Monte Carlo (MC) simulation and event reconstruction (i.e. inferring particle-decay events from experimental data) for long-term BaBar data preservation and analysis, the following software components have been designed: a language ('GraphPhys') for specifying decay processes, common to both simulation and data analysis, allowing arbitrary parameters on particles, decays, and entire processes; an automated visualization tool to show graphically what decays have been specified; and a searchable database storage mechanism for decay specifications. Unlike HepML, a proposed XML standard for HEP metadata, the specification language is designed not for data interchange between computer systems, but rather for direct manipulation by human beings as well as computers. The components are interoperable: the information parsed from files in the specification language can easily be rendered as an image by the visualization package, and conversion between decay representations was implemented. Several proof-of-concept command-line tools were built based on this framework. Applications include building easier and more efficient interfaces to existing analysis tools for current projects (e.g. BaBar/BESII), providing a framework for analyses in future experimental settings (e.g. LHC/SuperB), and outreach programs that involve giving students access to BaBar data and analysis tools to give them a hands-on feel for scientific analysis.

  4. Optimized Wang-Landau sampling of lattice polymers: Ground state search and folding thermodynamics of HP model proteins

    Science.gov (United States)

    Wüst, Thomas; Landau, David P.

    2012-08-01

    Coarse-grained (lattice-) models have a long tradition in aiding efforts to decipher the physical or biological complexity of proteins. Despite the simplicity of these models, however, numerical simulations are often computationally very demanding and the quest for efficient algorithms is as old as the models themselves. Expanding on our previous work [T. Wüst and D. P. Landau, Phys. Rev. Lett. 102, 178101 (2009)], 10.1103/PhysRevLett.102.178101, we present a complete picture of a Monte Carlo method based on Wang-Landau sampling in combination with efficient trial moves (pull, bond-rebridging, and pivot moves) which is particularly suited to the study of models such as the hydrophobic-polar (HP) lattice model of protein folding. With this generic and fully blind Monte Carlo procedure, all currently known putative ground states for the most difficult benchmark HP sequences could be found. For most sequences we could also determine the entire energy density of states and, together with suitably designed structural observables, explore the thermodynamics and intricate folding behavior in the virtually inaccessible low-temperature regime. We analyze the differences between random and protein-like heteropolymers for sequence lengths up to 500 residues. Our approach is powerful both in terms of robustness and speed, yet flexible and simple enough for the study of many related problems in protein folding.

  5. A new car-following model considering velocity anticipation

    Science.gov (United States)

    Tian, Jun-Fang; Jia, Bin; Li, Xin-Gang; Gao, Zi-You

    2010-01-01

    The full velocity difference model proposed by Jiang et al. [2001 Phys. Rev. E 64 017101] has been improved by introducing velocity anticipation. Velocity anticipation means the follower estimates the future velocity of the leader. The stability condition of the new model is obtained by using the linear stability theory. Theoretical results show that the stability region increases when we increase the anticipation time interval. The mKdV equation is derived to describe the kink-antikink soliton wave and obtain the coexisting stability line. The delay time of car motion and kinematic wave speed at jam density are obtained in this model. Numerical simulations exhibit that when we increase the anticipation time interval enough, the new model could avoid accidents under urgent braking cases. Also, the traffic jam could be suppressed by considering the anticipation velocity. All results demonstrate that this model is an improvement on the full velocity difference model.

  6. Post-construction evaluation of bird abundances and distributions in the Horns Rev 2 offshore wind farm area, 2011 and 2012

    DEFF Research Database (Denmark)

    Petersen, Ib Krag; Nielsen, Rasmus Due; Mackenzie, Monique L.

    2014-01-01

    Optællinger af fugle fra fly efter linjetransekt-metoden blev anvendt til at beskrive fuglenes antal og udbredelse i undersøgelsesområdet. Ti optællinger før Horns Rev 2 mølleparkens opførelse blev sammenlignet med ti optællinger foretaget efter parkens etablering. Rumlig modellering blev anvendt...

  7. Reply to “Comment on ‘Gauge invariance and k-factorization of exclusive processes’ [Phys. Lett. B 674 (2009) 176]” [Phys. Lett. B 674 (2009) 182

    Science.gov (United States)

    Feng, F.; Ma, J. P.; Wang, Q.

    2009-06-01

    A new method is proposed to calculate wave functions in kT-factorization in [H.-n. Li, S. Mishima, Phys. Lett. B 674 (2009) 182, arXiv:0808.1526] as a comment about our paper [F. Feng, J.P. Ma, Q. Wang, Phys. Lett. B 674 (2009) 176, arXiv:0807.0296]. We point out that the results obtained with the method are in conflict with the translation invariance and depend on the chosen contours for loop-integrals. Therefore, the method is in principle unacceptable and the results with the method cannot be correct.

  8. Thermodynamic Model Formulations for Inhomogeneous Solids with Application to Non-isothermal Phase Field Modelling

    Science.gov (United States)

    Gladkov, Svyatoslav; Kochmann, Julian; Reese, Stefanie; Hütter, Markus; Svendsen, Bob

    2016-04-01

    The purpose of the current work is the comparison of thermodynamic model formulations for chemically and structurally inhomogeneous solids at finite deformation based on "standard" non-equilibrium thermodynamics [SNET: e. g. S. de Groot and P. Mazur, Non-equilibrium Thermodynamics, North Holland, 1962] and the general equation for non-equilibrium reversible-irreversible coupling (GENERIC) [H. C. Öttinger, Beyond Equilibrium Thermodynamics, Wiley Interscience, 2005]. In the process, non-isothermal generalizations of standard isothermal conservative [e. g. J. W. Cahn and J. E. Hilliard, Free energy of a non-uniform system. I. Interfacial energy. J. Chem. Phys. 28 (1958), 258-267] and non-conservative [e. g. S. M. Allen and J. W. Cahn, A macroscopic theory for antiphase boundary motion and its application to antiphase domain coarsening. Acta Metall. 27 (1979), 1085-1095; A. G. Khachaturyan, Theory of Structural Transformations in Solids, Wiley, New York, 1983] diffuse interface or "phase-field" models [e. g. P. C. Hohenberg and B. I. Halperin, Theory of dynamic critical phenomena, Rev. Modern Phys. 49 (1977), 435-479; N. Provatas and K. Elder, Phase Field Methods in Material Science and Engineering, Wiley-VCH, 2010.] for solids are obtained. The current treatment is consistent with, and includes, previous works [e. g. O. Penrose and P. C. Fife, Thermodynamically consistent models of phase-field type for the kinetics of phase transitions, Phys. D 43 (1990), 44-62; O. Penrose and P. C. Fife, On the relation between the standard phase-field model and a "thermodynamically consistent" phase-field model. Phys. D 69 (1993), 107-113] on non-isothermal systems as a special case. In the context of no-flux boundary conditions, the SNET- and GENERIC-based approaches are shown to be completely consistent with each other and result in equivalent temperature evolution relations.

  9. Mechanisms of Avalanche Dynamics in a Stochastic Four-State Sandpile Model

    Institute of Scientific and Technical Information of China (English)

    张端明; 潘贵军; 雷雅洁

    2003-01-01

    We study the stochastic four-state sandpile model on the square lattice. The static and dynamical properties of the model are investigated and compared with the deterministic sandpile model of Bak, Tang, and Wiesenfeld [Phys. Rev. Lett. 59 (1987) 381]. The numerical results show that the stochastic model defines a new universality class with respect to the deterministic sandpile. We also find that the waves in an avalanche are uncorrelated in the stochastic model (in the BTW model, the waves in an avalanche are correlated). The physical origin of the critical behaviour of the stochastic model being different from that of the BTW model is ascribed to the ordering and deterministic property of the toppling law in the BTW model.

  10. Validating the effective-one-body model of spinning, precessing binary black holes against numerical relativity

    Science.gov (United States)

    Babak, Stanislav; Taracchini, Andrea; Buonanno, Alessandra

    2017-01-01

    In Abbott et al. [Phys. Rev. X 6, 041014 (2016), 10.1103/PhysRevX.6.041014], the properties of the first gravitational wave detected by LIGO, GW150914, were measured by employing an effective-one-body (EOB) model of precessing binary black holes whose underlying dynamics and waveforms were calibrated to numerical-relativity (NR) simulations. Here, we perform the first extensive comparison of such an EOBNR model to 70 precessing NR waveforms that span mass ratios from 1 to 5, dimensionless spin magnitudes up to 0.5, generic spin orientations, and length of about 20 orbits. We work in the observer's inertial frame and include all ℓ=2 modes in the gravitational-wave polarizations. We introduce new prescriptions for the EOB ringdown signal concerning its spectrum and time of onset. For total masses between 10 M⊙ and 200 M⊙ , we find that precessing EOBNR waveforms have unfaithfulness within about 3% to NR waveforms when considering the Advanced-LIGO design noise curve. This result is obtained without recalibration of the inspiral-plunge signal of the underlying nonprecessing EOBNR model. The unfaithfulness is computed with maximization over time and phase of arrival, sky location, and polarization of the EOBNR waveform, and it is averaged over sky location and polarization of the NR signal. We also present comparisons between NR and EOBNR waveforms in a frame that tracks the orbital precession.

  11. Nonequilibrium dynamics of spin-boson models from phase-space methods

    Science.gov (United States)

    Piñeiro Orioli, Asier; Safavi-Naini, Arghavan; Wall, Michael L.; Rey, Ana Maria

    2017-09-01

    An accurate description of the nonequilibrium dynamics of systems with coupled spin and bosonic degrees of freedom remains theoretically challenging, especially for large system sizes and in higher than one dimension. Phase-space methods such as the truncated Wigner approximation (TWA) have the advantage of being easily scalable and applicable to arbitrary dimensions. In this work we adapt the TWA to generic spin-boson models by making use of recently developed algorithms for discrete phase spaces [J. Schachenmayer, A. Pikovski, and A. M. Rey, Phys. Rev. X 5, 011022 (2015), 10.1103/PhysRevX.5.011022]. Furthermore we go beyond the standard TWA approximation by applying a scheme based on the Bogoliubov-Born-Green-Kirkwood-Yvon (BBGKY) hierarchy of equations to our coupled spin-boson model. This allows us, in principle, to study how systematically adding higher-order corrections improves the convergence of the method. To test various levels of approximation we study an exactly solvable spin-boson model, which is particularly relevant for trapped-ion arrays. Using TWA and its BBGKY extension we accurately reproduce the time evolution of a number of one- and two-point correlation functions in several dimensions and for an arbitrary number of bosonic modes.

  12. Flow regime transitions in dense non-Brownian suspensions: Rheology, microstructural characterization, and constitutive modeling

    Science.gov (United States)

    Ness, Christopher; Sun, Jin

    2015-01-01

    Shear flow of dense non-Brownian suspensions is simulated using the discrete element method taking particle contact and hydrodynamic lubrication into account. The resulting flow regimes are mapped in the parametric space of the solid volume fraction, shear rate, fluid viscosity, and particle stiffness. Below a critical volume fraction ϕc, the rheology is governed by the Stokes number, which distinguishes between viscous and inertial flow regimes. Above ϕc, a quasistatic regime exists for low and moderate shear rates. At very high shear rates, the ϕ dependence is lost, and soft-particle rheology is explored. The transitions between rheological regimes are associated with the evolving contribution of lubrication to the suspension stress. Transitions in microscopic phenomena, such as interparticle force distribution, fabric, and correlation length are found to correspond to those in the macroscopic flow. Motivated by the bulk rheology, a constitutive model is proposed combining a viscous pressure term with a dry granular model presented by Chialvo et al. [Phys. Rev. E 85, 021305 (2012), 10.1103/PhysRevE.85.021305]. The model is shown to successfully capture the flow regime transitions.

  13. Crossover Equation of State Models Applied to the Critical Behavior of Xenon

    Science.gov (United States)

    Garrabos, Y.; Lecoutre, C.; Marre, S.; Guillaument, R.; Beysens, D.; Hahn, I.

    2015-03-01

    The turbidity () measurements of Güttinger and Cannell (Phys Rev A 24:3188-3201, 1981) in the temperature range along the critical isochore of homogeneous xenon are reanalyzed. The singular behaviors of the isothermal compressibility () and the correlation length () predicted from the master crossover functions are introduced in the turbidity functional form derived by Puglielli and Ford (Phys Rev Lett 25:143-146, 1970). We show that the turbidity data are thus well represented by the Ornstein-Zernike approximant, within 1 % precision. We also introduce a new crossover master model (CMM) of the parametric equation of state for a simple fluid system with no adjustable parameter. The CMM model and the phenomenological crossover parametric model are compared with the turbidity data and the coexisting liquid-gas density difference (). The excellent agreement observed for , , , and in a finite temperature range well beyond the Ising-like preasymptotic domain confirms that the Ising-like critical crossover behavior of xenon can be described in conformity with the universal features estimated by the renormalization-group methods. Only 4 critical coordinates of the vapor-liquid critical point are needed in the (pressure, temperature, molecular volume) phase surface of xenon.

  14. Rev1 is a base excision repair enzyme with 5′-deoxyribose phosphate lyase activity

    Science.gov (United States)

    Prasad, Rajendra; Poltoratsky, Vladimir; Hou, Esther W.; Wilson, Samuel H.

    2016-01-01

    Rev1 is a member of the Y-family of DNA polymerases and is known for its deoxycytidyl transferase activity that incorporates dCMP into DNA and its ability to function as a scaffold factor for other Y-family polymerases in translesion bypass events. Rev1 also is involved in mutagenic processes during somatic hypermutation of immunoglobulin genes. In light of the mutation pattern consistent with dCMP insertion observed earlier in mouse fibroblast cells treated with a base excision repair-inducing agent, we questioned whether Rev1 could also be involved in base excision repair (BER). Here, we uncovered a weak 5′-deoxyribose phosphate (5′-dRP) lyase activity in mouse Rev1 and demonstrated the enzyme can mediate BER in vitro. The full-length Rev1 protein and its catalytic core domain are similar in their ability to support BER in vitro. The dRP lyase activity in both of these proteins was confirmed by NaBH4 reduction of the Schiff base intermediate and kinetics studies. Limited proteolysis, mass spectrometry and deletion analysis localized the dRP lyase active site to the C-terminal segment of Rev1's catalytic core domain. These results suggest that Rev1 could serve as a backup polymerase in BER and could potentially contribute to AID-initiated antibody diversification through this activity. PMID:27683219

  15. Rev1, Rev3, or Rev7 siRNA Abolishes Ultraviolet Light-Induced Translesion Replication in HeLa Cells: A Comprehensive Study Using Alkaline Sucrose Density Gradient Sedimentation

    Directory of Open Access Journals (Sweden)

    Jun Takezawa

    2010-01-01

    Full Text Available When a replicative DNA polymerase stalls upon encountering a lesion on the template strand, it is relieved by other low-processivity polymerase(s, which insert nucleotide(s opposite the lesion, extend by a few nucleotides, and dissociate from the 3′-OH. The replicative polymerase then resumes DNA synthesis. This process, termed translesion replication (TLS or replicative bypass, may involve at least five different polymerases in mammals, although the participating polymerases and their roles have not been entirely characterized. Using siRNAs originally designed and an alkaline sucrose density gradient sedimentation technique, we verified the involvement of several polymerases in ultraviolet (UV light-induced TLS in HeLa cells. First, siRNAs to Rev3 or Rev7 largely abolished UV-TLS, suggesting that these 2 gene products, which comprise Polζ, play a main role in mutagenic TLS. Second, Rev1-targeted siRNA also abrogated UV-TLS, indicating that Rev1 is also indispensable to mutagenic TLS. Third, Polη-targeted siRNA also prevented TLS to a greater extent than our expectations. Forth, although siRNA to Polι had no detectable effect, that to Polκ delayed UV-TLS. To our knowledge, this is the first study reporting apparent evidence for the participation of Polκ in UV-TLS.

  16. PhysTrack’: a Matlab based environment for video tracking of kinematics in the physics laboratory

    Science.gov (United States)

    Umar Hassan, Muhammad; Sabieh Anwar, Muhammad

    2017-07-01

    In the past two decades, several computer software tools have been developed to investigate the motion of moving bodies in physics laboratories. In this article we report a Matlab based video tracking library, PhysTrack, primarily designed to investigate kinematics. We compare PhysTrack with other commonly available video tracking tools and outline its salient features. The general methodology of the whole video tracking process is described with a step by step explanation of several functionalities. Furthermore, results of some real physics experiments are also provided to demonstrate the working of the automated video tracking, data extraction, data analysis and presentation tools that come with this development environment. We believe that PhysTrack will be valuable for the large community of physics teachers and students already employing Matlab.

  17. Rev-erb beta regulates the Srebp-1c promoter and mRNA expression in skeletal muscle cells

    Energy Technology Data Exchange (ETDEWEB)

    Ramakrishnan, Sathiya N.; Lau, Patrick; Crowther, Lisa M. [The University of Queensland, Institute for Molecular Bioscience, St. Lucia, Qld 4072 (Australia); Cleasby, Mark E. [Diabetes and Obesity Research Program, Garvan Institute of Medical Research, St. Vincent' s Hospital, 384 Victoria Street, Darlinghurst, Sydney, NSW 2010 (Australia); Millard, Susan; Leong, Gary M. [The University of Queensland, Institute for Molecular Bioscience, St. Lucia, Qld 4072 (Australia); Cooney, Gregory J. [Diabetes and Obesity Research Program, Garvan Institute of Medical Research, St. Vincent' s Hospital, 384 Victoria Street, Darlinghurst, Sydney, NSW 2010 (Australia); Muscat, George E.O., E-mail: g.muscat@imb.uq.edu.au [The University of Queensland, Institute for Molecular Bioscience, St. Lucia, Qld 4072 (Australia)

    2009-10-30

    The nuclear hormone receptor, Rev-erb beta operates as a transcriptional silencer. We previously demonstrated that exogenous expression of Rev-erb{beta}{Delta}E in skeletal muscle cells increased Srebp-1c mRNA expression. We validated these in vitro observations by injection of an expression vector driving Rev-erb{beta}{Delta}E expression into mouse tibialis muscle that resulted in increased Srebp-1c mRNA expression. Paradoxically, Rev-erb{beta} siRNA expression in skeletal muscle cells repressed Srebp-1c expression, and indicated that Rev-erb{beta} expression was necessary for Srebp-1c expression. ChIP analysis demonstrated that Rev-erb{beta} was recruited to the Srebp-1c promoter. Moreover, Rev-erb{beta} trans-activated the Srebp-1c promoter, in contrast, Rev-erb{beta} efficiently repressed the Rev-erb{alpha} promoter, a previously characterized target gene. Finally, treatment with the Rev-erb agonist (hemin) (i) increased the trans-activation of the Srebp-1c promoter by Rev-erb{beta}; and (ii) increased Rev-erb{beta} and Srebp-1c mRNA expression. These data suggest that Rev-erb{beta} has the potential to activate gene expression, and is a positive regulator of Srebp-1c, a regulator of lipogenesis.

  18. Scaling of the dynamics of a homogeneous one-dimensional anisotropic classical Heisenberg model with long-range interactions

    Science.gov (United States)

    Lourenço, C. R.; Rocha Filho, T. M.

    2015-07-01

    The dynamics of quasistationary states of long-range interacting systems with N particles can be described by kinetic equations such as the Balescu-Lenard and Landau equations. In the case of one-dimensional homogeneous systems, two-body contributions vanish as two-body collisions in one dimension only exchange momentum and thus cannot change the one-particle distribution. Using a Kac factor in the interparticle potential implies a scaling of the dynamics proportional to Nδ with δ =1 except for one-dimensional homogeneous systems. For the latter different values for δ were reported for a few models. Recently it was shown by Rocha Filho and collaborators [Phys. Rev. E 90, 032133 (2014)], 10.1103/PhysRevE.90.032133 for the Hamiltonian mean-field model that δ =2 provided that N is sufficiently large, while small N effects lead to δ ≈1.7 . More recently, Gupta and Mukamel [J. Stat. Mech. (2011) P03015, 10.1088/1742-5468/2011/03/P03015] introduced a classical spin model with an anisotropic interaction with a scaling in the dynamics proportional to N1.7 for a homogeneous state. We show here that this model reduces to a one-dimensional Hamiltonian system and that the scaling of the dynamics approaches N2 with increasing N . We also explain from theoretical consideration why usual kinetic theory fails for small N values, which ultimately is the origin of noninteger exponents in the scaling.

  19. High Affinity Heme Binding to a Heme Regulatory Motif on the Nuclear Receptor Rev-erbβ Leads to Its Degradation and Indirectly Regulates Its Interaction with Nuclear Receptor Corepressor.

    Science.gov (United States)

    Carter, Eric L; Gupta, Nirupama; Ragsdale, Stephen W

    2016-01-29

    Rev-erbα and Rev-erbβ are heme-binding nuclear receptors (NR) that repress the transcription of genes involved in regulating metabolism, inflammation, and the circadian clock. Previous gene expression and co-immunoprecipitation studies led to a model in which heme binding to Rev-erbα recruits nuclear receptor corepressor 1 (NCoR1) into an active repressor complex. However, in contradiction, biochemical and crystallographic studies have shown that heme decreases the affinity of the ligand-binding domain of Rev-erb NRs for NCoR1 peptides. One explanation for this discrepancy is that the ligand-binding domain and NCoR1 peptides used for in vitro studies cannot replicate the key features of the full-length proteins used in cellular studies. However, the combined in vitro and cellular results described here demonstrate that heme does not directly promote interactions between full-length Rev-erbβ (FLRev-erbβ) and an NCoR1 construct encompassing all three NR interaction domains. NCoR1 tightly binds both apo- and heme-replete FLRev-erbβ·DNA complexes; furthermore, heme, at high concentrations, destabilizes the FLRev-erbβ·NCoR1 complex. The interaction between FLRev-erbβ and NCoR1 as well as Rev-erbβ repression at the Bmal1 promoter appear to be modulated by another cellular factor(s), at least one of which is related to the ubiquitin-proteasome pathway. Our studies suggest that heme is involved in regulating the degradation of Rev-erbβ in a manner consistent with its role in circadian rhythm maintenance. Finally, the very slow rate constant (10(-6) s(-1)) of heme dissociation from Rev-erbβ rules out a prior proposal that Rev-erbβ acts as an intracellular heme sensor.

  20. Comment on “Temperature dependence of atomic vibrations in mono-layer graphene” [J. Appl. Phys. 118, 074302 (2015)

    Energy Technology Data Exchange (ETDEWEB)

    Susi, T., E-mail: toma.susi@univie.ac.at; Kotakoski, J. [Faculty of Physics, University of Vienna, Boltzmanngasse 5, 1090 Vienna (Austria)

    2016-02-14

    In an interesting recent study [Allen et al., J. Appl. Phys. 118, 074302 (2015)] (see also their Erratum [Allen et al., J. Appl. Phys. 118, 159902 (2015)]), Allen and co-workers measured the mean square amplitudes of graphene lattice vibrations between 100 and 1300 K and used a simplified theoretical approximation for the acoustic phonon modes to evaluate the maximum phonon wavelengths supported by the lattice. By fitting their data using the smallest wave-vector as the fitting parameter, they found this to be significantly smaller than the physical size of the graphene crystallites.

  1. A new method to estimate the uncertainty of AEP of offshore wind power plants applied to Horns Rev 1

    DEFF Research Database (Denmark)

    Murcia, Juan Pablo; Réthoré, Pierre-Elouan Mikael; Hansen, Kurt Schaldemose;

    2015-01-01

    The present article proposes a framework for validation of stationary wake models that wind developers can use to predict the energy production of a wind power plant more accurately. The application of this framework provides a new way to quantify the uncertainty of annual energy production...... Rev 1 offshore wind power plant. The model uncertainty of a modified N. O. Jensen wake model under uncertain undisturbed flow conditions was studied. Evidence of model inadequacy is found in terms of a bias in the predicted AEP distribution. It was found that the use of the official power curve...... compensates the errors in the wake model, as a consequence a larger uncertainty of the overall model is predicted. Furthermore a study of wake model benchmarking based on filtered flow cases indicates that measurement uncertainty in the wind speed and wind direction is large enough to obtain any evidence...

  2. A new method to estimate the uncertainty of AEP of offshore wind power plants applied to Horns Rev 1

    DEFF Research Database (Denmark)

    Murcia, Juan Pablo; Réthoré, Pierre-Elouan; Hansen, Kurt Schaldemose;

    2015-01-01

    Rev 1 offshore wind power plant. The model uncertainty of a modified N. O. Jensen wake model under uncertain undisturbed flow conditions was studied. Evidence of model inadequacy is found in terms of a bias in the predicted AEP distribution. It was found that the use of the official power curve......The present article proposes a framework for validation of stationary wake models that wind developers can use to predict the energy production of a wind power plant more accurately. The application of this framework provides a new way to quantify the uncertainty of annual energy production...... compensates the errors in the wake model, as a consequence a larger uncertainty of the overall model is predicted. Furthermore a study of wake model benchmarking based on filtered flow cases indicates that measurement uncertainty in the wind speed and wind direction is large enough to obtain any evidence...

  3. An integral equation model for warm and hot dense mixtures

    CERN Document Server

    Starrett, C E; Daligault, J; Hamel, S

    2014-01-01

    In Starrett and Saumon [Phys. Rev. E 87, 013104 (2013)] a model for the calculation of electronic and ionic structures of warm and hot dense matter was described and validated. In that model the electronic structure of one "atom" in a plasma is determined using a density functional theory based average-atom (AA) model, and the ionic structure is determined by coupling the AA model to integral equations governing the fluid structure. That model was for plasmas with one nuclear species only. Here we extend it to treat plasmas with many nuclear species, i.e. mixtures, and apply it to a carbon-hydrogen mixture relevant to inertial confinement fusion experiments. Comparison of the predicted electronic and ionic structures with orbital-free and Kohn-Sham molecular dynamics simulations reveals excellent agreement wherever chemical bonding is not significant.

  4. Modulational instability in the nonlocal chi(2)-model

    DEFF Research Database (Denmark)

    Wyller, John Andreas; Krolikowski, Wieslaw; Bang, Ole

    2007-01-01

    We investigate in detail the linear regime of the modulational instability (MI) properties of the plane waves of the nonlocal model for chi((2))- media formulated in Nikolov et al. [N.I. Nikolov, D. Neshev, O. Bang, W.Z. Krolikowski, Quadratic solitons as nonlocal solitons, Phys. Rev. E 68 (2003...... in the parameter space for which a fundamental gain band exists, and regions for which higher order gain bands and modulational stability exist. We also show that the MI analysis for the nonlocal model is applicable in the finite walk-off case. Finally, we show that the plane waves of the nonlocal chi((2))-model...... of the nonlocal chi((2))-model, by using the singular perturbational approach. The other branch of the plane waves (i.e. the nonadiabatic branch or the optical branch) is always modulationally unstable. We compare the MI results for the adiabatic branch with the predictions obtained from the full chi((2))-model...

  5. Rev-Erb co-regulates muscle regeneration via tethered interaction with the NF-Y cistrome

    Directory of Open Access Journals (Sweden)

    Ryan D. Welch

    2017-07-01

    Conclusions: Disrupting Rev-Erb activity in injured muscle accelerates regenerative muscle repair/differentiation through transcriptional de-repression of myogenic programs. Rev-Erb, therefore, may be a potent therapeutic target for a myriad of muscular disorders.

  6. Modeling of Quantum Transport in Semiconductor Devices (The Physics and Operation of Ultra-Submicron Length Semiconductor Devices).

    Science.gov (United States)

    1994-05-01

    and H. Launois, Microelectr. Engr. 6, 195 (1987). 6. C. Tiberio, E. D. Wolf, S. F. Anderson, W. J. Schaff , P. J. Tasker, and L. F. Eastman, J. Vac...P. Taylor, C. Dharma-Wardana, P. Zawadski, J. A. Adams , and P. T. Coleridge, Phys. Rev. B 47, 6811 (1993). 13 1M. Wagner, U. Merkt, and A. V...Coleridge, and J. A. Adams , Phys. Rev. Lett. 69, 1989 (1992). ൕM. Sumetskii, J. Phys. Cond. Matter 3, 2651 (1991). ’-"Y. Feng, A. S. Sachrajda, R. P

  7. Memristive model of amoeba learning

    Science.gov (United States)

    Pershin, Yuriy V.; La Fontaine, Steven; di Ventra, Massimiliano

    2010-03-01

    Recently, it was shown that the amoeba-like cell Physarum polycephalum when exposed to a pattern of periodic environmental changes learns and adapts its behavior in anticipation of the next stimulus to come. Here we show that such behavior can be mapped into the response of a simple electronic circuit consisting of a LC contour and a memory-resistor (a memristor) to a train of voltage pulses that mimic environment changes [1]. We also discuss a possible biological origin of the memristive behavior in the cell. These biological memory features are likely to occur in other unicellular as well as multicellular organisms, albeit in different forms. Therefore, the above memristive circuit model, which has learning properties, is useful to better understand the origins of primitive intelligence. [1] Yu. V. Pershin, S. La Fontaine, and M. Di Ventra, Phys. Rev. E 80, 021926 (2009)

  8. Elastic models of the fast traps of carnivorous Dionaea and Aldrovanda

    Science.gov (United States)

    Joyeux, Marc

    2013-09-01

    The carnivorous aquatic waterwheel plant (Aldrovanda vesiculosa L.) and the closely related terrestrial Venus flytrap (Dionaea muscipula Sol. ex J. Ellis) both feature elaborate snap-traps, which shut after reception of an external mechanical stimulus by prey animals. Although Aldrovanda is usually considered a miniature aquatic Dionaea, the shutting mechanisms of the two plants differ quite markedly. The fast shutting of Aldrovanda is indeed based on a simple swelling or shrinking mechanism, while the movement of Dionaea's traps is accelerated by the snap-buckling of the lobes. The purpose of this Brief Report is to describe several key improvements to the elastic models that have recently been introduced to elucidate these movements [Poppinga and Joyeux, Phys. Rev. EPLEEE81063-651X10.1103/PhysRevE.84.041928 84, 041928 (2011)]. In particular, a precise mechanism for the action of the motor cells of Aldrovanda is proposed, the facts that the opening of the leaves of Dionaea is an irreversible mechanism based on growth and that the strain field is anisotropic and much smaller on the inner than on the outer surface of the leaves during shutting are taken properly into account, and a more accurate formula for calculating mean curvatures is used. The improvements brought to the model are described in detail and the physical consequences of these improvements are discussed.

  9. Grain-scale modeling and splash parametrization for aeolian sand transport

    Science.gov (United States)

    Lämmel, Marc; Dzikowski, Kamil; Kroy, Klaus; Oger, Luc; Valance, Alexandre

    2017-02-01

    The collision of a spherical grain with a granular bed is commonly parametrized by the splash function, which provides the velocity of the rebounding grain and the velocity distribution and number of ejected grains. Starting from elementary geometric considerations and physical principles, like momentum conservation and energy dissipation in inelastic pair collisions, we derive a rebound parametrization for the collision of a spherical grain with a granular bed. Combined with a recently proposed energy-splitting model [Ho et al., Phys. Rev. E 85, 052301 (2012), 10.1103/PhysRevE.85.052301] that predicts how the impact energy is distributed among the bed grains, this yields a coarse-grained but complete characterization of the splash as a function of the impact velocity and the impactor-bed grain-size ratio. The predicted mean values of the rebound angle, total and vertical restitution, ejection speed, and number of ejected grains are in excellent agreement with experimental literature data and with our own discrete-element computer simulations. We extract a set of analytical asymptotic relations for shallow impact geometries, which can readily be used in coarse-grained analytical modeling or computer simulations of geophysical particle-laden flows.

  10. Multipseudopotential interaction: A consistent study of cubic equations of state in lattice Boltzmann models.

    Science.gov (United States)

    Khajepor, Sorush; Chen, Baixin

    2016-01-01

    A method is developed to analytically and consistently implement cubic equations of state into the recently proposed multipseudopotential interaction (MPI) scheme in the class of two-phase lattice Boltzmann (LB) models [S. Khajepor, J. Wen, and B. Chen, Phys. Rev. E 91, 023301 (2015)]10.1103/PhysRevE.91.023301. An MPI forcing term is applied to reduce the constraints on the mathematical shape of the thermodynamically consistent pseudopotentials; this allows the parameters of the MPI forces to be determined analytically without the need of curve fitting or trial and error methods. Attraction and repulsion parts of equations of state (EOSs), representing underlying molecular interactions, are modeled by individual pseudopotentials. Four EOSs, van der Waals, Carnahan-Starling, Peng-Robinson, and Soave-Redlich-Kwong, are investigated and the results show that the developed MPI-LB system can satisfactorily recover the thermodynamic states of interest. The phase interface is predicted analytically and controlled via EOS parameters independently and its effect on the vapor-liquid equilibrium system is studied. The scheme is highly stable to very high density ratios and the accuracy of the results can be enhanced by increasing the interface resolution. The MPI drop is evaluated with regard to surface tension, spurious velocities, isotropy, dynamic behavior, and the stability dependence on the relaxation time.

  11. Teede REV-2 otsustas börsile minna / Gea Velthut-Sokka

    Index Scriptorium Estoniae

    Velthut-Sokka, Gea, 1977-

    2004-01-01

    Eelmise aasta edukaima ehitusfirma Teede REV-2 ja tema suurinvestori Alta Kapital esindajad põhjendavad börsile mineku otsust. Tabelid ja diagrammid: Veerandi aktsiate omanikuvahetus börsilemineku peaprooviks

  12. Rev. Konstanty Michalski's life and work. On his 50th anniversary of death

    Directory of Open Access Journals (Sweden)

    Stanisław Piech

    1998-12-01

    Full Text Available The article outlines the life and work of Rev. Konstanty Michalski, a lecturer at the Department of Theology at the Jagiellonian University, on the fiftieth anniversary of his death (deceased in 1947.

  13. Multiple roles of Rev3, the catalytic subunit of polzeta in maintaining genome stability in vertebrates

    NARCIS (Netherlands)

    E. Sonoda (Eiichiro); S. Takeda (Shiunichi); T. Okada (Takashi); G.Y. Zhao (Guang); S. Tateishi (Satoshi); K. Araki (Kasumi); M. Yamaizumi (Masaru); T. Yagi (Takashi); N.S. Verkaik (Nicole); D.C. van Gent (Dik); M. Takata (Minoru)

    2003-01-01

    textabstractTranslesion DNA synthesis (TLS) and homologous DNA recombination (HR) are two major postreplicational repair (PRR) pathways. The REV3 gene of Saccharomyces cerevisiae encodes the catalytic subunit of DNA polymerase zeta, which is involved in mutagenic TLS. To

  14. 78 FR 27971 - Determination That REV-EYES (Dapiprazole Hydrochloride Ophthalmic Solution), 0.5%, Was Not...

    Science.gov (United States)

    2013-05-13

    ... HUMAN SERVICES Food and Drug Administration Determination That REV-EYES (Dapiprazole Hydrochloride... determined that REV-EYES (dapiprazole hydrochloride ophthalmic solution), 0.5%, was not withdrawn from sale... refer to a listed drug. REV-EYES (dapiprazole hydrochloride ophthalmic solution), 0.5%, is the...

  15. 75 FR 27840 - NUREG-0654/FEMA-REP-1, Rev. 1, Supplement 3, Guidance for Protective Action Recommendations for...

    Science.gov (United States)

    2010-05-18

    ...: 2010-11842] NUCLEAR REGULATORY COMMISSION [NRC-2010-0080] NUREG-0654/FEMA-REP-1, Rev. 1, Supplement 3...: ``NUREG-0654/FEMA-REP-1, Rev. 1, Supplement 3, Guidance for Protective Action Recommendations for General... the existing guidance contained in Supplement 3 to NUREG- 0654/FEMA-REP-1, Rev. 1, ``Criteria...

  16. 75 FR 10524 - NUREG-0654/FEMA-REP-1, Rev. 1, Supplement 3, Guidance for Protective Action Recommendations for...

    Science.gov (United States)

    2010-03-08

    ... COMMISSION NUREG-0654/FEMA-REP-1, Rev. 1, Supplement 3, Guidance for Protective Action Recommendations for... document entitled: ``NUREG-0654/FEMA-REP-1, Rev. 1, Supplement 3, Guidance for Protective Action...-4737, or by e-mail to pdr.resource@nrc.gov . NUREG-0654/FEMA-REP-1, Rev. 1, Supplement 3,...

  17. Open Rabi model with ultrastrong coupling plus large dispersive-type nonlinearity: Nonclassical light via a tailored degeneracy

    Science.gov (United States)

    Grimsmo, Arne L.; Parkins, Scott

    2014-03-01

    We consider a generalized version of the Rabi model that includes a nonlinear, dispersive-type atom-field interaction in addition to the usual linear dipole coupling, as well as cavity dissipation. An effective system of this sort arises, for example, in a quantum simulation of the Rabi model based upon Raman transitions in an optical cavity QED setting [A. L. Grimsmo and S. Parkins, Phys. Rev. A 87, 033814 (2013), 10.1103/PhysRevA.87.033814]. For a range of the nonlinear interaction strength about a special value, degeneracies or near degeneracies of the states in the cavity-mode vacuum and single-photon subspaces, in combination with cavity loss, gives rise to an essentially closed cycle of excitations and photon emissions within these subspaces. Consequently, the cavity output field is strongly antibunched, while over this range of nonlinear strengths the atomic population undergoes an abrupt inversion. We develop a quantum-trajectory-based description of the system that models its key properties very well, and use a simple dressed-state picture to explain the novel structure of the cavity fluorescence spectrum. We also present numerical results for a potential realization of the system using a rubidium atom coupled strongly to a high-finesse optical cavity mode.

  18. Density-functional theory and Monte Carlo simulations of the phase behavior of a simple model liquid crystal

    Science.gov (United States)

    Giura, Stefano; Schoen, Martin

    2014-08-01

    We consider the phase behavior of a simple model of a liquid crystal by means of modified mean-field density-functional theory (MMF DFT) and Monte Carlo simulations in the grand canonical ensemble (GCEMC). The pairwise additive interactions between liquid-crystal molecules are modeled via a Lennard-Jones potential in which the attractive contribution depends on the orientation of the molecules. We derive the form of this orientation dependence through an expansion in terms of rotational invariants. Our MMF DFT predicts two topologically different phase diagrams. At weak to intermediate coupling of the orientation dependent attraction, there is a discontinuous isotropic-nematic liquid-liquid phase transition in addition to the gas-isotropic liquid one. In the limit of strong coupling, the gas-isotropic liquid critical point is suppressed in favor of a fluid- (gas- or isotropic-) nematic phase transition which is always discontinuous. By considering three representative isotherms in parallel GCEMC simulations, we confirm the general topology of the phase diagram predicted by MMF DFT at intermediate coupling strength. From the combined MMF DFT-GCEMC approach, we conclude that the isotropic-nematic phase transition is very weakly first order, thus confirming earlier computer simulation results for the same model [see M. Greschek and M. Schoen, Phys. Rev. E 83, 011704 (2011), 10.1103/PhysRevE.83.011704].

  19. Comment on : "A novel approach for solving the Fisher equation using Exp-function method" [Phys. Lett. A 372 3836

    NARCIS (Netherlands)

    Kudryashov, Nikolai A.

    2009-01-01

    Using Exp-function method Ozis and Koroglu [T. Ozis, C. Koroglu, Phys. Lett. A 372 (2008) 3836] have found exact "solutions" of the Fisher equation. In this comment we demonstrate that all these solutions do not satisfy the Fisher equation. The efficiency of application of Exp-function method to sea

  20. Comment on "Soret motion in non-ionic binary molecular mixtures" [J. Chem. Phys. 135, 054102 (2011)].

    Science.gov (United States)

    Semenov, Semen N; Schimpf, Martin E

    2012-09-28

    The material transport equations derived in the article by Leroyer and Würger [J. Chem. Phys. 135, 054102 (2011)] do not adequately provide a description of material transport in liquid binary systems. An alternate approach based on non-equilibrium thermodynamics is presented.

  1. Comment on "Structure and properties of reduced LaCoO3" [J. Appl. Phys. 44, 5553 (1973)

    Science.gov (United States)

    Zhang, A. M.

    2013-06-01

    A hexagonal crystal lattice with the perovskite structure can be treated as rhombohedral or pseudocubic structure. The publication by Sis and Wirtz [J. Appl. Phys. 44, 5553 (1973)] presented a schematic diagram to explain these relationships, but made a mistake in the hexagonal lattice, which is corrected here.

  2. Multi-Faceted Post-Transcriptional Functions of HIV-1 Rev

    Directory of Open Access Journals (Sweden)

    Kuan-Teh Jeang

    2012-07-01

    Full Text Available Post-transcriptional regulation of HIV-1 gene expression is largely governed by the activities of the viral Rev protein. In this minireview, the multiple post-transcriptional activities of Rev in the export of partially spliced and unspliced HIV-1 RNAs from the nucleus to the cytoplasm, in the translation of HIV-1 transcripts, and in the packaging of viral genomic RNAs are reviewed in brief.

  3. Offshore wind farms in the local environment - an examination at Horns Rev Offshore Wind Farm. Background report; Havvindmoeller i lokalomraadet - en undersoegelse ved Horns Rev Havmoellepark. Baggrundsrapport

    Energy Technology Data Exchange (ETDEWEB)

    Kuehn, Susanne

    2005-07-01

    Horns Rev Offshore Wind Farm was built in 2002. A presentation is made of a sociological, qualitative survey on the local community's reception of the offshore wind farm. The survey aims at identifying attitudes towards the farm before and after the construction, with a view to identifying possible changes in attitudes, and explain the reasons for these (ml)

  4. Application of RevPASH index in restaurant management%RevPASH指标在餐饮管理中的应用

    Institute of Scientific and Technical Information of China (English)

    王琪

    2013-01-01

    随着社会经济水平的提高,我国的餐饮业发展非常迅速。餐饮业和其他企业一样,也需要做好管理,而RevPASH指标作为一种重要的管理方法已在餐饮业得到了广泛的应用。文章主要对RevPASH指标在餐饮管理中的应用做了探讨。%With the improvement of socio-economic level, catering industry in our country is developing very quickly. The catering industry and other enterprises, also need to do a good job in the management, and take RevPASH index as an important management method, has been widely used in the food and beverage industry. This paper explored the application of RevPASH index in restaurant management.

  5. Unperturbed posttranscriptional regulatory Rev protein function and HIV-1 replication in astrocytes.

    Directory of Open Access Journals (Sweden)

    Ashok Chauhan

    Full Text Available Astrocytes protect neurons, but also evoke proinflammatory responses to injury and viral infections, including HIV. There is a prevailing notion that HIV-1 Rev protein function in astrocytes is perturbed, leading to restricted viral replication. In earlier studies, our finding of restricted viral entry into astrocytes led us to investigate whether there are any intracellular restrictions, including crippled Rev function, in astrocytes. Despite barely detectable levels of DDX3 (Rev-supporting RNA helicase and TRBP (anti-PKR in primary astrocytes compared to astrocytic cells, Rev function was unperturbed in wild-type, but not DDX3-ablated astrocytes. As in permissive cells, after HIV-1 entry bypass in astrocytes, viral-encoded Tat and Rev proteins had robust regulatory activities, leading to efficient viral replication. Productive HIV-1 infection in astrocytes persisted for several weeks. Our findings on HIV-1 entry bypass in astrocytes demonstrated that the intracellular environment is conducive to viral replication and that Tat and Rev functions are unperturbed.

  6. Efficient numerical methods for the random-field Ising model: Finite-size scaling, reweighting extrapolation, and computation of response functions.

    Science.gov (United States)

    Fytas, Nikolaos G; Martín-Mayor, Víctor

    2016-06-01

    It was recently shown [Phys. Rev. Lett. 110, 227201 (2013)PRLTAO0031-900710.1103/PhysRevLett.110.227201] that the critical behavior of the random-field Ising model in three dimensions is ruled by a single universality class. This conclusion was reached only after a proper taming of the large scaling corrections of the model by applying a combined approach of various techniques, coming from the zero- and positive-temperature toolboxes of statistical physics. In the present contribution we provide a detailed description of this combined scheme, explaining in detail the zero-temperature numerical scheme and developing the generalized fluctuation-dissipation formula that allowed us to compute connected and disconnected correlation functions of the model. We discuss the error evolution of our method and we illustrate the infinite limit-size extrapolation of several observables within phenomenological renormalization. We present an extension of the quotients method that allows us to obtain estimates of the critical exponent α of the specific heat of the model via the scaling of the bond energy and we discuss the self-averaging properties of the system and the algorithmic aspects of the maximum-flow algorithm used.

  7. Simple nonlinear models suggest variable star universality

    CERN Document Server

    Lindner, John F; Kia, Behnam; Hippke, Michael; Learned, John G; Ditto, William L

    2015-01-01

    Dramatically improved data from observatories like the CoRoT and Kepler spacecraft have recently facilitated nonlinear time series analysis and phenomenological modeling of variable stars, including the search for strange (aka fractal) or chaotic dynamics. We recently argued [Lindner et al., Phys. Rev. Lett. 114 (2015) 054101] that the Kepler data includes "golden" stars, whose luminosities vary quasiperiodically with two frequencies nearly in the golden ratio, and whose secondary frequencies exhibit power-law scaling with exponent near -1.5, suggesting strange nonchaotic dynamics and singular spectra. Here we use a series of phenomenological models to make plausible the connection between golden stars and fractal spectra. We thereby suggest that at least some features of variable star dynamics reflect universal nonlinear phenomena common to even simple systems.

  8. Exactly solvable cellular automaton traffic jam model.

    Science.gov (United States)

    Kearney, Michael J

    2006-12-01

    A detailed study is undertaken of the v{max}=1 limit of the cellular automaton traffic model proposed by Nagel and Paczuski [Phys. Rev. E 51, 2909 (1995)]. The model allows one to analyze the behavior of a traffic jam initiated in an otherwise freely flowing stream of traffic. By mapping onto a discrete-time queueing system, itself related to various problems encountered in lattice combinatorics, exact results are presented in relation to the jam lifetime, the maximum jam length, and the jam mass (the space-time cluster size or integrated vehicle waiting time), both in terms of the critical and the off-critical behavior. This sets existing scaling results in their natural context and also provides several other interesting results in addition.

  9. Scaling model for symmetric star polymers

    Science.gov (United States)

    Ramachandran, Ram; Rai, Durgesh K.; Beaucage, Gregory

    2010-03-01

    Neutron scattering data from symmetric star polymers with six poly (urethane-ether) arms, chemically bonded to a C-60 molecule are fitted using a new scaling model and scattering function. The new scaling function can describe both good solvent and theta solvent conditions as well as resolve deviations in chain conformation due to steric interactions between star arms. The scaling model quantifies the distinction between invariant topological features for this star polymer and chain tortuosity which changes with goodness of solvent and steric interaction. Beaucage G, Phys. Rev. E 70 031401 (2004).; Ramachandran R, et al. Macromolecules 41 9802-9806 (2008).; Ramachandran R, et al. Macromolecules, 42 4746-4750 (2009); Rai DK et al. Europhys. Lett., (Submitted 10/2009).

  10. Complex Behaviors of a Simple Traffic Model

    Institute of Scientific and Technical Information of China (English)

    GAO Xing-Ru

    2006-01-01

    In this paper, we propose a modified traffic model in which a single car moves through a sequence of traffic lights controlled by a step function instead of a sine function. In contrast to the previous work [Phys. Rev. E 70 (2004)016107], we have investigated in detail the dependence of the behavior on four parameters, ω, α, η, and a1, and given three kinds of bifurcation diagrams, which show three kinds of complex behaviors. We have found that in this model there are chaotic and complex periodic motions, as well as special singularities. We have also analyzed the characteristic of the complex period motion and the essential feature of the singularity.

  11. Nonequilibrium Steady States of a Stochastic Model System.

    Science.gov (United States)

    Zhang, Qiwei

    We study the nonequilibrium steady state of a stochastic lattice gas model, originally proposed by Katz, Lebowitz and Spohn (Phys. Rev. B 28: 1655 (1983)). Firstly, we solve the model on some small lattices exactly in order to see the general dependence of the steady state upon different parameters of the model. Nextly, we derive some analytical results for infinite lattice systems by taking some suitable limits. We then present some renormalization group results for the continuum version of the model via field theoretical techniques, the supersymmetry of the critical dynamics in zero field is also explored. Finally, we report some very recent 3-D Monte Carlo simulation results, which have been obtained by applying Multi-Spin-Coding techniques on a CDC vector supercomputer - Cyber 205 at John von Neumann Center.

  12. Robustness of a Cellular Automata Model for the HIV Infection

    CERN Document Server

    Figueirêdo, P H; Santos, R M Zorzenon dos

    2008-01-01

    An investigation was conducted to study the robustness of the results obtained from the cellular automata model which describes the spread of the HIV infection within lymphoid tissues [R. M. Zorzenon dos Santos and S. Coutinho, Phys. Rev. Lett. 87, 168102 (2001)]. The analysis focussed on the dynamic behavior of the model when defined in lattices with different symmetries and dimensionalities. The results illustrated that the three-phase dynamics of the planar models suffered minor changes in relation to lattice symmetry variations and, while differences were observed regarding dimensionality changes, qualitative behavior was preserved. A further investigation was conducted into primary infection and sensitiveness of the latency period to variations of the model's stochastic parameters over wide ranging values. The variables characterizing primary infection and the latency period exhibited power-law behavior when the stochastic parameters varied over a few orders of magnitude. The power-law exponents were app...

  13. Contact angles in the pseudopotential lattice Boltzmann modeling of wetting

    CERN Document Server

    Li, Q; Kang, Q J; Chen, Q

    2014-01-01

    In this paper, we aim to investigate the implementation of contact angles in the pseudopotential lattice Boltzmann modeling of wetting at a large density ratio. The pseudopotential lattice Boltzmann model [X. Shan and H. Chen, Phys. Rev. E 49, 2941 (1994)] is a popular mesoscopic model for simulating multiphase flows and interfacial dynamics. In this model, the contact angle is usually realized by a fluid-solid interaction. Two widely used fluid-solid interactions: the density-based interaction and the pseudopotential-based interaction, as well as a modified pseudopotential-based interaction formulated in the present paper, are numerically investigated and compared in terms of the achievable contact angles, the maximum and the minimum densities, and the spurious currents. It is found that the pseudopotential-based interaction works well for simulating small static (liquid) contact angles, however, is unable to reproduce static contact angles close to 180 degrees. Meanwhile, it is found that the proposed modif...

  14. Numerical simulations of the 2-dimensional Robin-Hood model

    Science.gov (United States)

    Cwilich, Gabriel; Fox, Perry; Zypman, Fredy; Buldyrev, Sergey

    2007-03-01

    The Robin Hood, or Zaitsev model [1] has been successfully used to model depinning of interfaces, friction, dislocation motion and flux creep, because it is one of the simplest extremal models for self-organized criticallity Until now, its properties have been well understood theoretically in one dimension and its scaling laws numerically verified. It is important to extend the range of validity of these laws into higher dimensions, to find precise values for the scaling exponents, and to investigate how they depend on the details of the model (like anisotropy). The case of two dimensions is of particular importance when studying surface friction [2]. Here, we numerically evaluate high precision scaling exponents for the avalanche size distribution, the avalanche fractal dimension, and the Levy flight-like distribution of the jumps between extremal active sites. [1] S.I. Zaitsev , Physica A 189, 411 (1992). [2] S. Buldyrev, J. Ferrante and F. Zypman Phys. Rev E (accepted)

  15. Infauna monitoring Horns Rev offshore wind farm. Annual state report 2004

    Energy Technology Data Exchange (ETDEWEB)

    Bech, M.; Frederiksen, R.; Pedersen, John; Leonhard, S.B.

    2005-04-15

    A total of 40 species were identified from the surveys in the Horns Rev area in September 2004 while 42 species were identified in 2003 and 47 species in September 2001. The decline in the number of species occurred both inside the wind farm and reference areas, which indicates that the decline could be a combination of changes in sediment characteristics and natural variation rather than an effect from the establishment of the wind farm. More species were not associated with the hard substrate at the turbine sites in 2004 compared to 2003, while in 2001, more species were associated with fine-grained sand. The median sediment grain size increased from 2001 to 2003 to 2004, which suggests that the velocity of the current increased, but modelling calculations on current speed predicted a 2% reduction in the wind farm area and up to a 15% reduction very close to the scour protection. These results agreed with the grain sizes found at the stations 5, 25 and 100 metres from the scour protection. At most stations, the medium grain size was 5 metres lower from the scour protection compared with the station 100 metres from the scour protection, which indicates that the velocity of the current was lower close to the scour protection. No significant impact on the infauna in the wind farm area was detectable concerning distance-related effects. Though general reductions in the population size of some of the character species in the surveyed areas might be related to changes in the sediment structure, the infauna community at Horns Rev showed no obvious sign of stress response as a consequence of possible impact from construction and operating activities. New species were observed in 2003 and 2004 and some of these might be a result of sediment characteristics, less predation or natural variation. The recording of other species might be a result of the introduction of hard bottom habitants in the wind farm area. The density of the most abundant bivalves and bristle worms was

  16. Random Neighbor Theory of the Olami-Feder-Christensen Earthquake Model

    CERN Document Server

    Broeker, H M

    1997-01-01

    We derive the exact equations of motion for the random neighbor version of the Olami-Feder-Christensen earthquake model in the infinite-size limit. We solve them numerically, and compare with simulations of the model for large numbers of sites. We find perfect agreement. But we do not find any scaling or phase transitions, except in the conservative limit. This is in contradiction to claims by Lise & Jensen (Phys. Rev. Lett. 76, 2326 (1996)) based on approximate solutions of the same model. It indicates again that scaling in the Olami-Feder-Christensen model is only due to partial synchronization driven by spatial inhomogeneities. Finally, we point out that our method can be used also for other SOC models, and treat in detail the random neighbor version of the Feder-Feder model.

  17. Density of states of continuous and discrete spin models: a case study

    Science.gov (United States)

    Nardini, Cesare; Nerattini, Rachele; Casetti, Lapo

    2012-02-01

    A relation between O(n) lattice spin models and Ising models defined on the same lattice was recently put forward (Casetti et al 2011 Phys. Rev. Lett. 106 057208). Such a relation, inspired by an energy landscape analysis, implies that the density of states of an O(n) spin model on a lattice can be effectively approximated, at least close to the phase transition, in terms of the density of states of an Ising model defined on the same lattice and with the same interactions. In this paper we show that such a relation exactly holds, albeit in a slightly modified form, in the special cases of the mean-field XY model and the one-dimensional XY model. We also discuss the possible consequences of this result for the general case.

  18. Direct and Indirect Suppression of Interleukin-6 Gene Expression in Murine Macrophages by Nuclear Orphan Receptor REV-ERBα

    Directory of Open Access Journals (Sweden)

    Shogo Sato

    2014-01-01

    Full Text Available It is now evident that many nuclear hormone receptors can modulate target gene expression. REV-ERBα, one of the nuclear hormone receptors with the capacity to alter clock function, is critically involved in lipid metabolism, adipogenesis, and the inflammatory response. Recent studies suggest that REV-ERBα plays a key role in the mediation between clockwork and inflammation. The purpose of the current study was to investigate the role of REV-ERBα in the regulation of interleukin-6 (il6 gene expression in murine macrophages. REV-ERBα agonists, or overexpression of rev-erbα in the murine macrophage cell line RAW264 cells, suppressed the induction of il6 mRNA following a lipopolysaccharide (LPS endotoxin challenge. Also, rev-erbα overexpression decreased LPS-stimulated nuclear factor κB (NFκB activation in RAW264 cells. We showed that REV-ERBα represses il6 expression not only indirectly through an NFκB binding motif but also directly through a REV-ERBα binding motif in the murine il6 promoter region. Furthermore, peritoneal macrophages from mice lacking rev-erbα increased il6 mRNA expression. These data suggest that REV-ERBα regulates the inflammatory response of macrophages through the suppression of il6 expression. REV-ERBα may therefore be identified as a potent anti-inflammatory receptor and be a therapeutic target receptor of inflammatory diseases.

  19. Nullbasic, a potent anti-HIV tat mutant, induces CRM1-dependent disruption of HIV rev trafficking.

    Directory of Open Access Journals (Sweden)

    Min-Hsuan Lin

    Full Text Available Nullbasic, a mutant of the HIV-1 Tat protein, has anti-HIV-1 activity through mechanisms that include inhibition of Rev function and redistribution of the HIV-1 Rev protein from the nucleolus to the nucleoplasm and cytoplasm. Here we investigate the mechanism of this effect for the first time, establishing that redistribution of Rev by Nullbasic is not due to direct interaction between the two proteins. Rather, Nullbasic affects subcellular localization of cellular proteins that regulate Rev trafficking. In particular, Nullbasic induced redistribution of exportin 1 (CRM1, nucleophosmin (B23 and nucleolin (C23 from the nucleolus to the nucleus when Rev was coexpressed, but never in its absence. Inhibition of the Rev:CRM1 interaction by leptomycin B or a non-interacting RevM10 mutant completely blocked redistribution of Rev by Nullbasic. Finally, Nullbasic did not inhibit importin β- or transportin 1-mediated nuclear import, suggesting that cytoplasmic accumulation of Rev was due to increased export by CRM1. Overall, our data support the conclusion that CRM1-dependent subcellular redistribution of Rev from the nucleolus by Nullbasic is not through general perturbation of either nuclear import or export. Rather, Nullbasic appears to interact with and disrupt specific components of a Rev trafficking complex required for its nucleocytoplasmic shuttling and, in particular, its nucleolar accumulation.

  20. REVS: a radar-based enhanced vision system for degraded visual environments

    Science.gov (United States)

    Brailovsky, Alexander; Bode, Justin; Cariani, Pete; Cross, Jack; Gleason, Josh; Khodos, Victor; Macias, Gary; Merrill, Rahn; Randall, Chuck; Rudy, Dean

    2014-06-01

    Sierra Nevada Corporation (SNC) has developed an enhanced vision system utilizing fast-scanning 94 GHz radar technology to provide three-dimensional measurements of an aircraft's forward external scene topography. This threedimensional data is rendered as terrain imagery, from the pilot's perspective, on a Head-Up Display (HUD). The image provides the requisite "enhanced vision" to continue a safe approach along the flight path below the Decision Height (DH) in Instrument Meteorological Conditions (IMC) that would otherwise be cause for a missed approach. Terrain imagery is optionally fused with digital elevation model (DEM) data of terrain outside the radar field of view, giving the pilot additional situational awareness. Flight tests conducted in 2013 show that REVS™ has sufficient resolution and sensitivity performance to allow identification of requisite visual references well above decision height in dense fog. This paper provides an overview of the Enhanced Flight Vision System (EFVS) concept, of the technology underlying REVS, and a detailed discussion of the flight test results.

  1. Parity-odd and CPT-even electrodynamics of the standard model extension at finite temperature

    Science.gov (United States)

    Casana, Rodolfo; Ferreira, Manoel M., Jr.; Silva, Madson R. O.

    2010-05-01

    This work examines the finite temperature properties of the CPT-even and parity-odd electrodynamics of the standard model extension. The starting point is the partition function computed for an arbitrary and sufficiently small tensor (kF)ανρφ [see R. Casana, M. M. Ferreira, Jr., J. S. Rodrigues, and M. R. O. Silva, Phys. Rev. DPRVDAQ1550-7998 80, 085026 (2009).10.1103/PhysRevD.80.085026]. After specializing the Lorentz-violating tensor (kF)ανρφ for the leading-order-nonbirefringent and parity-odd coefficients, the partition function is explicitly carried out, showing that it is a power of the Maxwell partition function. Also, it is observed that the Lorentz invariance violation coefficients induce an anisotropy in the black-body angular energy density distribution. Planck’s radiation law retains its usual frequency dependence and the Stefan-Boltzmann law keeps the same form, except for a global proportionality constant.

  2. Quantum-annealing correction at finite temperature: Ferromagnetic p -spin models

    Science.gov (United States)

    Matsuura, Shunji; Nishimori, Hidetoshi; Vinci, Walter; Albash, Tameem; Lidar, Daniel A.

    2017-02-01

    The performance of open-system quantum annealing is adversely affected by thermal excitations out of the ground state. While the presence of energy gaps between the ground and excited states suppresses such excitations, error correction techniques are required to ensure full scalability of quantum annealing. Quantum annealing correction (QAC) is a method that aims to improve the performance of quantum annealers when control over only the problem (final) Hamiltonian is possible, along with decoding. Building on our earlier work [S. Matsuura et al., Phys. Rev. Lett. 116, 220501 (2016), 10.1103/PhysRevLett.116.220501], we study QAC using analytical tools of statistical physics by considering the effects of temperature and a transverse field on the penalty qubits in the ferromagnetic p -body infinite-range transverse-field Ising model. We analyze the effect of QAC on second (p =2 ) and first (p ≥3 ) order phase transitions, and construct the phase diagram as a function of temperature and penalty strength. Our analysis reveals that for sufficiently low temperatures and in the absence of a transverse field on the penalty qubit, QAC breaks up a single, large free-energy barrier into multiple smaller ones. We find theoretical evidence for an optimal penalty strength in the case of a transverse field on the penalty qubit, a feature observed in QAC experiments. Our results provide further compelling evidence that QAC provides an advantage over unencoded quantum annealing.

  3. Two-photon-exchange effects in the unpolarized μ p scattering within a hadronic model

    Science.gov (United States)

    Zhou, Hai-Qing

    2017-02-01

    In this work, the two-photon-exchange (TPE) effects in the unpolarized μ p scattering are discussed within the hadronic model where the intermediate states N ,Δ , and σ are considered. The contribution from the N intermediate is close to the results given by Tomalak and Vanderhaeghen [Phys. Rev. D 90, 013006 (2014)], 10.1103/PhysRevD.90.013006 at small Q , and there is a sizable difference when Q >0.25 GeV (where Q2 is the four-momentum transfer). The contributions from the Δ and the σ intermediate states are much smaller than that from the N intermediate at small Q . In the kinematic region with ki⊆[0.01 ,0.3 ] GeV and Q ≤0.4 GeV (where ki is the three-momentum of initial muon in the laboratory frame), a naive expression for the TPE contributions is given, which can be used directly for other analysis.

  4. Useful models of four-wave mixing in Bose Einstein condensates

    Science.gov (United States)

    Infeld, E.; Trippenbach, M.

    2003-11-01

    A recent experiment demonstrated four-wave mixing of wavepackets in a sodium Bose-Einstein condensate (Deng et al 1999 Nature 398 218). This was followed by a theoretical and numerical treatment of the experiment (Trippenbach et al 2000 Phys. Rev. A 62 02368). In the experiment, a short period of free expansion of the condensate, after release from the magnetic trap, was followed by a set of two Bragg pulses which created moving wavepackets. These wavepackets, due to nonlinear interaction and under phase-matching conditions, created a new momentum component in a four-wave mixing process. We propose simple mathematical models for this process. Next we suggest that, instead of exactly matching the frequencies as in the abovementioned experiments, we introduce a small mismatch in the energies, and therefore the frequencies Dgrohgr. We show that such a small mismatch can compensate for the initial phases that are built on the condensate during free expansion. A physical explanation is offered. This compensation can improve the efficiency of four-wave mixing; in some cases even increasing it by a factor of 2. We also deal with the situation where two strong wavepackets are accompanied by a weak input beam applied as a seed both with and without a mismatch. Here the influence of the mismatch is less obviously beneficial. We also comment on recent work by Ketterle's group (Vogels et al 2002 Phys. Rev. Lett. 89 020401).

  5. Impact of REV-ERB alpha gene polymorphisms on obesity phenotypes in adult and adolescent samples.

    Science.gov (United States)

    Goumidi, L; Grechez, A; Dumont, J; Cottel, D; Kafatos, A; Moreno, L A; Molnar, D; Moschonis, G; Gottrand, F; Huybrechts, I; Dallongeville, J; Amouyel, P; Delaunay, F; Meirhaeghe, A

    2013-05-01

    REV-ERBα has been shown to regulate adipogenesis and lipid metabolism as well as to link the circadian timing system to whole body metabolic homeostasis. We thus tested whether polymorphisms in REV-ERBα could be associated with metabolic phenotypes in human population samples. We analyzed the associations between 5 REV-ERBα polymorphisms and anthropometric (body weight, body mass index (BMI), waist and hip circumferences), biochemical (plasma lipid, glucose and insulin levels) and clinical (systolic and diastolic blood pressure) variables in three population-based studies (MONICA Lille n=1155 adults, MONA LISA Lille n=1170 adults and HELENA n=1155 adolescents). We assessed in vitro, the potential influence of one REV-ERBα polymorphism in transient transfection assays using two different cell lines. We observed significant and consistent associations between the T minor allele of the REV-ERBα rs2071427 polymorphism (located in intron 1) and higher BMI (mean allele effect=+0.33 kg m(-2)) in the MONICA Lille (P=0.02), MONA LISA (P=0.02) and HELENA (P=0.03) studies. The odds ratios for obesity associated with this allele were 1.67 (1.00-2.79) (P=0.05) in MONICA Lille, 1.29 (1.01-1.65) (P=0.04) in MONA LISA Lille and the odds ratio for overweight was 1.48 (1.08-2.03) (P=0.01) in HELENA. In transfection experiments in human hepatocyte-derived cell lines, the REV-ERBα intron 1 directed the transcription of a luciferase reporter gene independently of the rs2071427 polymorphism. Our results suggest that the REV-ERBα rs2071427 polymorphism modulates body fat mass in both adult and young people.

  6. REV-ERBalpha participates in circadian SREBP signaling and bile acid homeostasis.

    Directory of Open Access Journals (Sweden)

    Gwendal Le Martelot

    2009-09-01

    Full Text Available In mammals, many aspects of behavior and physiology, and in particular cellular metabolism, are coordinated by the circadian timing system. Molecular clocks are thought to rely on negative feedback loops in clock gene expression that engender oscillations in the accumulation of transcriptional regulatory proteins, such as the orphan receptor REV-ERBalpha. Circadian transcription factors then drive daily rhythms in the expression of clock-controlled output genes, for example genes encoding enzymes and regulators of cellular metabolism. To gain insight into clock output functions of REV-ERBalpha, we carried out genome-wide transcriptome profiling experiments with liver RNA from wild-type mice, Rev-erbalpha knock-out mice, or REV-ERBalpha overexpressing mice. On the basis of these genetic loss- and gain-of-function experiments, we concluded that REV-ERBalpha participates in the circadian modulation of sterol regulatory element-binding protein (SREBP activity, and thereby in the daily expression of SREBP target genes involved in cholesterol and lipid metabolism. This control is exerted via the cyclic transcription of Insig2, encoding a trans-membrane protein that sequesters SREBP proteins to the endoplasmic reticulum membranes and thereby interferes with the proteolytic activation of SREBPs in Golgi membranes. REV-ERBalpha also participates in the cyclic expression of cholesterol-7alpha-hydroxylase (CYP7A1, the rate-limiting enzyme in converting cholesterol to bile acids. Our findings suggest that this control acts via the stimulation of LXR nuclear receptors by cyclically produced oxysterols. In conclusion, our study suggests that rhythmic cholesterol and bile acid metabolism is not just driven by alternating feeding-fasting cycles, but also by REV-ERBalpha, a component of the circadian clockwork circuitry.

  7. HRensembleHR. High resolution ensemble for Horns Rev. Final project report; Offshore wind power

    Energy Technology Data Exchange (ETDEWEB)

    2010-03-15

    The wind farm output of an offshore-farm such as Horns Rev changes between nearly constant output to highly variable power output. A balance responsible will therefore benefit from knowing the variability of a wind farm in advance. Some understanding of the observed variability and the corresponding forecast error on offshore wind farms had been gathered in the past few years, while a large fraction (about 60%) of the error still lacked understanding and required further intense research. This was the outset at the beginning of the HREnsemble project. Results from the wave study, variability study, ocean coupling, findings from the sensitivity experiments, the iEnKF short-term forecast and finally the demonstration phase have given significant synergy. The most basic research result in the project is that the two empirical mode decomposition approaches, Hilbert-Huang and later the Ensemble Empirical Mode Decomposition (EEMD). Both approaches confirmed that significant variability exists in offshore conditions. It was found that the variability of the short time-scales (24 minutes) are either not explicitly visible in the grid-scale of the NWP models or in the best case significantly smoothed out in all of the tested model configurations. If we interpret 2/3 of the variability due to vertical waves not present in the mean flow and 1/3 of the variability due to meso-scale weather, then the model results and EEMD are consistent. We can however not verify this theory. At present we do not know if EEMD counts neither the events correct nor whether the ensemble forecast suppresses variability. The existence of variability above the time-scale related to friction between ocean waves and air can in fact explain some of the inconsistent results published in the literature and set a question mark behind the correctness of the calculation of friction in wave, ocean and weather modelling. (LN)

  8. Study of a model equation in detonation theory: multidimensional effects

    CERN Document Server

    Faria, Luiz M; Rosales, Rodolfo R

    2015-01-01

    We extend the reactive Burgers equation presented in Kasimov et al. Phys. Rev. Lett., 110 (2013) and Faria et al. SIAM J. Appl. Maths, 74 (2014), to include multidimensional effects. Furthermore, we explain how the model can be rationally justified following the ideas of the asymptotic theory developed in Faria et al. JFM (2015). The proposed model is a forced version of the unsteady small disturbance transonic flow equations. We show that for physically reasonable choices of forcing functions, traveling wave solutions akin to detonation waves exist. It is demonstrated that multidimensional effects play an important role in the stability and dynamics of the traveling waves. Numerical simulations indicate that solutions of the model tend to form multi-dimensional patterns analogous to cells in gaseous detonations.

  9. Multifractal heart rate dynamics in human cardiovascular model

    Science.gov (United States)

    Kotani, Kiyoshi; Takamasu, Kiyoshi; Safonov, Leonid; Yamamoto, Yoshiharu

    2003-05-01

    Human cardiovascular and/or cardio-respiratory systems are shown to exhibit both multifractal and synchronous dynamics, and we recently developed a nonlinear, physiologically plausible model for the synchronization between heartbeat and respiration (Kotani, et al. Phys. Rev. E 65: 051923, 2002). By using the same model, we now show the multifractality in the heart rate dynamics. We find that beat-to-beat monofractal noise (fractional Brownian motion) added to the brain stem cardiovascular areas results in significantly broader singularity spectra for heart rate through interactions between sympathetic and parasympathetic nervous systems. We conclude that the model proposed here would be useful in studying the complex cardiovascular and/or cardio- respiratory dynamics in humans.

  10. Effects of alpha stopping power modelling on the ignition threshold in a directly-driven inertial confinement fusion capsule

    Science.gov (United States)

    Temporal, Mauro; Canaud, Benoit; Cayzac, Witold; Ramis, Rafael; Singleton, Robert L.

    2017-05-01

    The alpha-particle energy deposition mechanism modifies the ignition conditions of the thermonuclear Deuterium-Tritium fusion reactions, and constitutes a key issue in achieving high gain in Inertial Confinement Fusion implosions. One-dimensional hydrodynamic calculations have been performed with the code Multi-IFE [R. Ramis, J. Meyer-ter-Vehn, Comput. Phys. Commun. 203, 226 (2016)] to simulate the implosion of a capsule directly irradiated by a laser beam. The diffusion approximation for the alpha energy deposition has been used to optimize three laser profiles corresponding to different implosion velocities. A Monte-Carlo package has been included in Multi-IFE to calculate the alpha energy transport, and in this case the energy deposition uses both the LP [C.K. Li, R.D. Petrasso, Phys. Rev. Lett. 70, 3059 (1993)] and the BPS [L.S. Brown, D.L. Preston, R.L. Singleton Jr., Phys. Rep. 410, 237 (2005)] stopping power models. Homothetic transformations that maintain a constant implosion velocity have been used to map out the transition region between marginally-igniting and high-gain configurations. The results provided by the two models have been compared and it is found that - close to the ignition threshold - in order to produce the same fusion energy, the calculations performed with the BPS model require about 10% more invested energy with respect to the LP model.

  11. Spin g -factor due to electronic interactions in graphene

    Science.gov (United States)

    Menezes, Natália; Alves, Van Sérgio; Marino, E. C.; Nascimento, Leonardo; Nascimento, Leandro O.; Morais Smith, C.

    2017-06-01

    The gyromagnetic factor is an important physical quantity relating the magnetic-dipole moment of a particle to its spin. The electron spin g -factor in vacuo is one of the best model-based theoretical predictions ever made, showing agreement with the measured value up to ten parts per trillion [J. Schwinger, Phys. Rev. 73, 416 (1948), 10.1103/PhysRev.73.416; R. S. Van Dyck, Jr. et al., Phys. Rev. Lett. 59, 26 (1987), 10.1103/PhysRevLett.59.26; D. Hanneke et al., Phys. Rev. Lett. 100, 120801 (2008), 10.1103/PhysRevLett.100.120801; T. Aoyama et al., Phys. Rev. Lett. 109, 111807 (2012), 10.1103/PhysRevLett.109.111807]. However, for electrons in a material the g -factor is modified with respect to its value in vacuo because of environment interactions. Here, we show how interaction effects lead to the spin g -factor correction in graphene by considering the full electromagnetic interaction in the framework of pseudo-QED [A. Kovner et al., Phys. Rev. B 42, 4748 (1990), 10.1103/PhysRevB.42.4748; N. Dorey et al., Nucl. Phys. B 386, 614 (1992), 10.1016/0550-3213(92)90632-L; S. Teber, Phys. Rev. D 86, 025005 (2012), 10.1103/PhysRevD.86.025005; S. Teber, Phys. Rev. D 89, 067702 (2014), 10.1103/PhysRevD.89.067702; E. C. Marino, Nucl. Phys. B 408, 551 (1993), 10.1016/0550-3213(93)90379-4]. We compare our theoretical prediction with experiments performed on graphene deposited on SiO2 and SiC, and we find a very good agreement between them.

  12. Comments on ``Lightning return stroke. A numerical calculation of the optical radiation'' [Phys. Fluids 29, 2736 (1986)

    Science.gov (United States)

    Hill, R. D.

    1987-08-01

    It is noted that the energy computed by Paxton et al. [Phys. Fluids 29, 2736 (1986)] for the dissipation in unit length of a typical lightning channel is much less than a widely quoted experimental value, and also less than an earlier computed value. A further comment on the work of Paxton et al. that a large fraction of energy is ``radiated away,'' is also made.

  13. Baryon-Baryon Interactions ---Nijmegen Extended-Soft-Core Models---

    Science.gov (United States)

    Rijken, T. A.; Nagels, M. M.; Yamamoto, Y.

    We review the Nijmegen extended-soft-core (ESC) models for the baryon-baryon (BB) interactions of the SU(3) flavor-octet of baryons (N, Lambda, Sigma, and Xi). The interactions are basically studied from the meson-exchange point of view, in the spirit of the Yukawa-approach to the nuclear force problem [H. Yukawa, ``On the interaction of Elementary Particles I'', Proceedings of the Physico-Mathematical Society of Japan 17 (1935), 48], using generalized soft-core Yukawa-functions. These interactions are supplemented with (i) multiple-gluon-exchange, and (ii) structural effects due to the quark-core of the baryons. We present in some detail the most recent extended-soft-core model, henceforth referred to as ESC08, which is the most complete, sophisticated, and successful interaction-model. Furthermore, we discuss briefly its predecessor the ESC04-model [Th. A. Rijken and Y. Yamamoto, Phys. Rev. C 73 (2006), 044007; Th. A. Rijken and Y. Yamamoto, Ph ys. Rev. C 73 (2006), 044008; Th. A. Rijken and Y. Yamamoto, nucl-th/0608074]. For the soft-core one-boson-exchange (OBE) models we refer to the literature [Th. A. Rijken, in Proceedings of the International Conference on Few-Body Problems in Nuclear and Particle Physics, Quebec, 1974, ed. R. J. Slobodrian, B. Cuec and R. Ramavataram (Presses Universitè Laval, Quebec, 1975), p. 136; Th. A. Rijken, Ph. D. thesis, University of Nijmegen, 1975; M. M. Nagels, Th. A. Rijken and J. J. de Swart, Phys. Rev. D 17 (1978), 768; P. M. M. Maessen, Th. A. Rijken and J. J. de Swart, Phys. Rev. C 40 (1989), 2226; Th. A. Rijken, V. G. J. Stoks and Y. Yamamoto, Phys. Rev. C 59 (1999), 21; V. G. J. Stoks and Th. A. Rijken, Phys. Rev. C 59 (1999), 3009]. All ingredients of these latter models are also part of ESC08, and so a description of ESC08 comprises all models so far in principle. The extended-soft-core (ESC) interactions consist of local- and non-local-potentials due to (i) one-boson-exchanges (OBE), which are the members of nonets of

  14. cdma2000 1x EV-DO Rev.A的多流分组应用%MFPA of cdma2000 1x EV-DO Rev.A

    Institute of Scientific and Technical Information of China (English)

    摩托罗拉公司

    2007-01-01

    cdma2000 1x EV-DO版本A(即release A)将是中国CDMA运营商的3G选择.为使用户能同时支持不同QoS的实时应用,EV-DO Rev.A的数据平面引入了多流分组应用.为配合MFPA的应用,分组数据业务节点(PDSN)亦须做相应的升级.

  15. Two-dimensional lattice Boltzmann model for compressible flows with high Mach number

    Science.gov (United States)

    Gan, Yanbiao; Xu, Aiguo; Zhang, Guangcai; Yu, Xijun; Li, Yingjun

    2008-03-01

    In this paper we present an improved lattice Boltzmann model for compressible Navier-Stokes system with high Mach number. The model is composed of three components: (i) the discrete-velocity-model by M. Watari and M. Tsutahara [Phys. Rev. E 67 (2003) 036306], (ii) a modified Lax-Wendroff finite difference scheme where reasonable dissipation and dispersion are naturally included, (iii) artificial viscosity. The improved model is convenient to compromise the high accuracy and stability. The included dispersion term can effectively reduce the numerical oscillation at discontinuity. The added artificial viscosity helps the scheme to satisfy the von Neumann stability condition. Shock tubes and shock reflections are used to validate the new scheme. In our numerical tests the Mach numbers are successfully increased up to 20 or higher. The flexibility of the new model makes it suitable for tracking shock waves with high accuracy and for investigating nonlinear nonequilibrium complex systems.

  16. Evidence against a three-phase point in a binary hard-core lattice model

    Science.gov (United States)

    Verberkmoes, Alain; Nienhuis, Bernard

    1999-09-01

    Using Monte Carlo simulation, Van Duijneveldt and Lekkerkerker [Phys. Rev. Lett. 71, 4264 (1993)] found gas-liquid-solid behavior in a simple two-dimensional lattice model with two types of hard particles. The same model is studied here by means of numerical transfer-matrix calculations, focusing on the finite-size scaling of the gaps between the largest few eigenvalues. No evidence for a gas-liquid transition is found. We discuss the relation of the model with a solvable restricted solid-on-solid model of which the states obey the same exclusion rules. Finally, a detailed analysis of the relation with the dilute three-state Potts model strongly supports the tricritical point rather than a three-phase point.

  17. Comment on "An optimized potential for carbon dioxide" [J. Chem. Phys. 122, 214507 (2005)

    OpenAIRE

    Merker, T.; Vrabec, J.; Hasse, H.

    2009-01-01

    A molecular model for carbon dioxide is assessed regarding vapor-liquid quilibrium properties.Large deviations, being above 15 %, are found for vapor pressure and saturated vapor density in the entire temperature range.

  18. Models of GexSe1-x

    Science.gov (United States)

    Malouin, Marc-André.; Mousseau, Normand

    2008-03-01

    We present numerical models of chalcogenide glasses constructed using the effective two and three body interaction potential developed by Mauro and Varshneya [1] combined with the activation-relaxation technique (ART nouveau) [2]. Structures are prepared starting from a random distribution, avoiding biases and crystalline remnants. Structural properties are studied mainly via characteristic system measurements including partial and total radial distribution functions, bond angle distributions, mean coordinations and bonds population. Results are shown for GexSe1-x for various x concentrations and compared to both experimental measurements and ab initio simulation results. [1] J.C. Mauro and A.K. Varshneya, J. Am. Ceram. Soc., 89 [7] 2323-6 (2006). [2] R. Malek and N. Mousseau, Phys. Rev. E 62, 7723 (2000).

  19. Description of collective and quasiparticle excitations in deformed actinide nuclei: The first application of the Heavy Shell Model

    CERN Document Server

    Cui, Ji-Wei; Chen, Fang-Qi; Sun, Yang; Wu, Cheng-Li; Gao, Zao-Chun

    2014-01-01

    The Heavy Shell Model (HSM) (Y. Sun and C.-L. Wu, Phys. Rev. C 68, 024315 (2003)) was proposed to take the advantages of two existing models, the projected shell model (PSM) and the Fermion Dynamical Symmetry Model (FDSM). To construct HSM, one extends the PSM by adding collective D-pairs into the intrinsic basis. The HSM is expected to describe simultaneously low-lying collective and quasi-particle excitations in deformed nuclei, and still keeps the model space tractable even for the heaviest systems. As the first numerical realization of the HSM, we study systematically the band structures for some deformed actinide nuclei, with a model space including up to 4-quasiparticle and 1-D-pair configurations. The calculated energy levels for the ground- state bands, the collective bands such as {\\beta} - and {\\gamma} -bands, and some quasiparticle bands agree well with known experimental data. Some low-lying quasiparticle bands are predicted, awaiting experimental confirmation.

  20. Scalar composite boson masses in the SU(2){sub TC} x SU(3){sub L} x U(1){sub x} model and the normalized Bethe-Salpeter equation

    Energy Technology Data Exchange (ETDEWEB)

    Gomes, Adriano Doff Sotta [Universidade Tecnologica Federal do Parana (UTFPR), Pato Branco, PR (Brazil)

    2011-07-01

    Full text: Scalar composite boson masses have been computed in QCD and Technicolor theories with the help of the homogeneous Bethe-Salpeter equation (BSE), resulting in a scalar mass that is twice the dynamically generated fermion or technifermion mass (m{sub dyn}). In the A. Doff, A. A. Natale and P. S. Rodrigues da Silva, Phys. Rev. D 80, 055005 (2009) we study the effect of the normalization condition on the determination of scalar boson masses in dynamically broken gauge theories and verify that the normalization condition does not modify the value of the scalar boson mass when its wave function has the asymptotic behavior exactly as predicted by the OPE. However in walking (or quasi-conformal) gauge theories the asymptotic behavior of fermionic self-energies and the wave function of scalar bound states are dominated by higher order interactions and are characterized by a much harder decrease with the momentum, therefore, in this case, we show that the normalization condition of the BSE do constrain the scalar masses. In this work we apply some results obtained in the cited reference to the model described in A. Doff, Phys. Rev. D 81, 117702 (2010), in particular we compute the Higgs boson masses generated in the model assuming the effects of mixing in the wave function of scalar bound states due to the U(1){sub x} interaction of U' and D' techniquarks. (author)

  1. Ion Beam Synthesis of Ge Nanowires. rev. ed.

    Energy Technology Data Exchange (ETDEWEB)

    Mueller, T.

    2001-01-01

    The formation of Ge nanowires in V-grooves has been studied experimentally as well as theoretically. As substrate oxide covered Si V-grooves were used formed by anisotropic etching of (001)Si wafers and subsequent oxidation of their surface. Implantation of 1 x 10{sup 17} Ge{sup +}cm{sup -2} at 70 keV was carried out into the oxide layer covering the V-grooves. Ion irradiation induces shape changes of the V-grooves, which are captured in a novel continuum model of surface evolution. It describes theoretically the effects of sputtering, redeposition of sputtered atoms, and swelling. Thereby, the time evolution of the target surface is determined by a nonlinear integro-differential equation, which was solved numerically for the V-groove geometry. A very good agreement is achieved for the predicted surface shape and the shape observed in XTEM images. Surprisingly, the model predicts material (Si, O, Ge) transport into the V-groove bottom which also suggests an Ge accumulation there proven by STEM-EDX investigations. In this Ge rich bottom region, subsequent annealing in N{sub 2} atmosphere results in the formation of a nanowire by coalescence of Ge precipitates shown by XTEM images. The process of phase separation during the nanowire growth was studied by means of kinetic 3D lattice Monte-Carlo simulations. These simulations also indicate the disintegration of continuous wires into droplets mediated by thermal fluctuations. Energy considerations have identified a fragmentation threshold and a lower boundary for the droplet radii which were confirmed by the Monte Carlo simulation. The here given results indicate the possibility of achieving nanowires being several nanometers wide by further growth optimizations as well as chains of equally spaced clusters with nearly uniform diameter. (orig.)

  2. Implications for (d ,p ) reaction theory from nonlocal dispersive optical model analysis of 40Ca(d ,p )41Ca

    Science.gov (United States)

    Waldecker, S. J.; Timofeyuk, N. K.

    2016-09-01

    The nonlocal dispersive optical model (NLDOM) nucleon potentials are used for the first time in the adiabatic analysis of a (d ,p ) reaction to generate distorted waves both in the entrance and exit channels. These potentials were designed and fitted by Mahzoon et al. [Phys. Rev. Lett. 112, 162503 (2014), 10.1103/PhysRevLett.112.162503] to constrain relevant single-particle physics in a consistent way by imposing the fundamental properties, such as nonlocality, energy-dependence and dispersive relations, that follow from the complex nature of nuclei. However, the NLDOM prediction for the 40Ca(d ,p )41Ca cross sections at low energy, typical for some modern radioactive beam ISOL (isotope separation online) facilities, is about 70% higher than the experimental data despite being reduced by the NLDOM spectroscopic factor of 0.73. This overestimation comes most likely either from insufficient absorption or due to constructive interference between ingoing and outgoing waves. This indicates strongly that additional physics arising from many-body effects is missing in the widely used current versions of (d ,p ) reaction theories.

  3. Phase transitions in a frustrated biquadratic Heisenberg model with coupled orbital degrees of freedom for iron-based superconductors

    Science.gov (United States)

    Zhuo, W. Z.; Qin, M. H.; Dong, S.; Li, X. G.; Liu, J.-M.

    2016-03-01

    In this paper, we study a biquadratic Heisenberg model with coupled orbital degrees of freedom by using a Monte Carlo simulation to investigate the phase transitions in iron-based superconductors. The antiferroquadrupolar state, which may be related to the magnetism of FeSe [R. Yu and Q. Si, Phys. Rev. Lett. 115, 116401 (2015), 10.1103/PhysRevLett.115.116401], is stabilized by the anisotropic biquadratic interaction induced by a ferro-orbital-ordered state. It is revealed that the orbital and nematic transitions occur at the same temperature for all the cases, supporting the mechanism of the orbital-driven nematicity as revealed in most recent experiments [S. H. Baek, D. V. Efremov, J. M. Ok, J. S. Kim, J. van den Brink, and B. Büchner, Nat. Mater. 14, 210 (2015), 10.1038/nmat4138]. In addition, it is suggested that the orbital interaction may lead to the separation of the structural and magnetic phase transitions, as observed in many families of iron pnictides.

  4. Cluster Luttinger liquids and emergent supersymmetric conformal critical points in the one-dimensional soft-shoulder Hubbard model

    Science.gov (United States)

    Dalmonte, M.; Lechner, W.; Cai, Zi; Mattioli, M.; Läuchli, A. M.; Pupillo, G.

    2015-07-01

    We investigate the quantum phases of hard-core bosonic atoms in an extended Hubbard model where particles interact via soft-shoulder potentials in one dimension. Using a combination of field-theoretical methods and strong-coupling perturbation theory, we demonstrate that the low-energy phase can be a conformal cluster Luttinger liquid (CLL) phase with central charge c =1 , where the microscopic degrees of freedom correspond to mesoscopic ensembles of particles. Using numerical density-matrix renormalization-group methods, we demonstrate that the CLL phase [first predicted in M. Mattioli et al., Phys. Rev. Lett. 111, 165302 (2013), 10.1103/PhysRevLett.111.165302] is separated from a conventional Tomonaga-Luttinger liquid by an exotic critical point with central charge c =3/2 . The latter is expression of an emergent conformal supersymmetry, which is not present in the original Hamiltonian. We discuss the observability of the CLL phase in realistic experimental settings with weakly dressed Rydberg atoms confined to optical lattices. Using quantum Monte Carlo simulations, we show that the typical features of CLLs are stable up to comparatively high temperatures. Using exact diagonalizations and quantum trajectory methods, we provide a protocol for adiabatic state preparation as well as quantitative estimates on the effects of particle losses.

  5. Circuit models and three-dimensional electromagnetic simulations of a 1-MA linear transformer driver stage

    Directory of Open Access Journals (Sweden)

    D. V. Rose

    2010-09-01

    Full Text Available A 3D fully electromagnetic (EM model of the principal pulsed-power components of a high-current linear transformer driver (LTD has been developed. LTD systems are a relatively new modular and compact pulsed-power technology based on high-energy density capacitors and low-inductance switches located within a linear-induction cavity. We model 1-MA, 100-kV, 100-ns rise-time LTD cavities [A. A. Kim et al., Phys. Rev. ST Accel. Beams 12, 050402 (2009PRABFM1098-440210.1103/PhysRevSTAB.12.050402] which can be used to drive z-pinch and material dynamics experiments. The model simulates the generation and propagation of electromagnetic power from individual capacitors and triggered gas switches to a radially symmetric output line. Multiple cavities, combined to provide voltage addition, drive a water-filled coaxial transmission line. A 3D fully EM model of a single 1-MA 100-kV LTD cavity driving a simple resistive load is presented and compared to electrical measurements. A new model of the current loss through the ferromagnetic cores is developed for use both in circuit representations of an LTD cavity and in the 3D EM simulations. Good agreement between the measured core current, a simple circuit model, and the 3D simulation model is obtained. A 3D EM model of an idealized ten-cavity LTD accelerator is also developed. The model results demonstrate efficient voltage addition when driving a matched impedance load, in good agreement with an idealized circuit model.

  6. Empirical investigation of wind farm blockage effects in Horn Rev 1 offshore wind farm

    DEFF Research Database (Denmark)

    Mitraszewski, Karol; Hansen, Kurt Schaldemose; Nygaard, Nicolai;

    We present an empirical study of wind farm blockage effects based on Horns Rev 1 SCADA data. The mean inflow non-uniformities in wind speed are analyzed by calculating the mean power outputs of turbines located along the outer edges of the farm for different wind directions, wind speeds and stabi......We present an empirical study of wind farm blockage effects based on Horns Rev 1 SCADA data. The mean inflow non-uniformities in wind speed are analyzed by calculating the mean power outputs of turbines located along the outer edges of the farm for different wind directions, wind speeds...

  7. Administrative Circular No. 13 (Rev. 4) - Guarantees for representatives of the personnel

    CERN Multimedia

    Department Head Office - HR Department

    2016-01-01

    Administrative Circular No. 13 (Rev. 4) entitled "Guarantees for representatives of the personnel", approved by the Director-General following discussion in the Standing Concertation Committee meeting on 22 March 2016, will be available on 1st September 2016 via the following link: https://cds.cern.ch/record/2208527.   This revised circular cancels and replaces Administrative Circular No. 13 (Rev. 3) also entitled "Guarantees for representatives of the personnel" of January 2014. This document contains a single change to reflect the terminology under the new career structure: the term "career path" is replaced by "grade". This circular will enter into force on 1st September 2016.

  8. Unprecedented NES non-antagonistic inhibitor for nuclear export of Rev from Sida cordifolia.

    Science.gov (United States)

    Tamura, Satoru; Kaneko, Masafumi; Shiomi, Atsushi; Yang, Guang-Ming; Yamaura, Toshiaki; Murakami, Nobutoshi

    2010-03-15

    Bioassay-guided separation from the MeOH extract of the South American medicinal plant Sida cordifolia resulted in isolation of (10E,12Z)-9-hydroxyoctadeca-10,12-dienoic acid (1) as an unprecedented NES non-antagonistic inhibitor for nuclear export of Rev. This mechanism of action was established by competitive experiment by the biotinylated probe derived from leptomycin B, the known NES antagonistic inhibitor. Additionally, structure-activity relationship analysis by use of the synthesized analogs clarified cooperation of several functionalities in the Rev-export inhibitory activity of 1. Copyright 2010 Elsevier Ltd. All rights reserved.

  9. Rev-erbα and the circadian transcriptional regulation of metabolism

    DEFF Research Database (Denmark)

    Gerhart-Hines, Z.; Lazar, M. A.

    2015-01-01

    The circadian clock orchestrates the coordinated rhythmicity of numerous metabolic pathways to anticipate daily and seasonal changes in energy demand. This vital physiol. function is controlled by a set of individual clock components that are present in each cell of the body, and regulate each...... other as well as clock output genes. A key factor is the nuclear receptor, Rev-erbα, a transcriptional repressor which functions not only as a clock component but also as a modulator of metabolic programming in an array of tissues. This review explores the role of Rev-erbα in mediating this crosstalk...

  10. Administrative Circular No. 11 (Rev. 4) - Categories of members of the personnel

    CERN Multimedia

    HR Department

    2016-01-01

    Administrative Circular No. 11 (Rev. 4) entitled "Categories of members of the personnel", approved by the Director-General following discussion in the Standing Concertation Committee meeting on 29 April 2016, will be available on 1 August 2016 via this following link.    This revised circular cancels and replaces the Administrative Circular No. 11 (Rev. 3) also entitled "Categories of members of the personnel" of September 2014. The main changes concern the status of apprentices and their transfer from the category of employed members of personnel to associated members of personnel. This circular will enter into force on 1 August 2016. Department Head Office

  11. Investigations of migratory birds during operation of Horns Rev offshore wind farm. Annual status report 2004

    Energy Technology Data Exchange (ETDEWEB)

    Kjaer Christensen, T.; Hounisen, J.P. [NERI, Dept. of Wildlife Ecology and Biodiversity, Roskilde (Denmark)

    2005-07-01

    The aim of the project is to assess the collision risk between birds and wind turbines at the Horns Rev wind farm. The study focused on describing bird movements in relation to the wind farm and to identify the species-specific behavioural responses towards the wind turbines shown by migrating and staging bird species. The study was based on data from spring 2004. The Horns Rev area lies in a region known to be of importance for substantial water bird migration as well as holding internationally important numbers of several wintering and staging water bird species. (au)

  12. Administrative Circular No. 22B (Rev. 2) - Compensation for hours of long-term shift work

    CERN Multimedia

    Department Head Office - HR Department

    2016-01-01

    Administrative Circular No. 22B (Rev. 2) entitled "Compensation for hours of long-term shift work",  approved by the Director-General following discussion in the Standing Concertation Committee meeting on 22 March 2016, will be available on 1st September 2016 via the following link: https://cds.cern.ch/record/2208538.   This revised circular cancels and replaces Administrative Circular No. 22B (Rev. 1) also entitled "Compensation for hours of long-term shift work" of March 2011. This document contains minor changes to reflect the new career structure. This circular will enter into force on 1st September 2016.

  13. Physics of organic semiconductors. 2. compl. new rev. ed.

    Energy Technology Data Exchange (ETDEWEB)

    Bruetting, Wolfgang [Augsburg Univ. (Germany). Inst. fuer Physik; Adachi, Chihaya (eds.) [Kyushu Univ., Fukuoka (Japan). Center for Future Chemistry

    2012-07-01

    The field of organic electronics has seen a steady growth over the last 15 years. At the same time, our scientific understanding of how to achieve optimum device performance has grown, and this book gives an overview of our present-day knowledge of the physics behind organic semiconductor devices. Based on the very successful first edition, the editors have invited top scientists from the US, Japan, and Europe to include the developments from recent years, covering such fundamental issues as: - growth and characterization of thin films of organic semiconductors, - charge transport and photophysical properties of the materials as well as their electronic structure at interfaces, and - analysis and modeling of devices like organic light-emitting diodes or organic lasers. The result is an overview of the field for both readers with basic knowledge and for an application-oriented audience. It thus bridges the gap between textbook knowledge largely based on crystalline molecular solids and those books focusing more on device applications.

  14. A numerical-statistical approach to determining the representative elementary volume (REV of cement paste for measuring diffusivity

    Directory of Open Access Journals (Sweden)

    Zhang, M. Z.

    2010-12-01

    Full Text Available Concrete diffusivity is a function of its microstructure on many scales, ranging from nanometres to millimetres. Multi-scale techniques are therefore needed to model this parameter. Representative elementary volume (REV, in conjunction with the homogenization principle, is one of the most common multi-scale approaches. This study aimed to establish a procedure for establishing the REV required to determine cement paste diffusivity based on a three-step, numerical-statistical approach. First, several series of 3D cement paste microstructures were generated with HYMOSTRUC3D, a cement hydration and microstructure model, for different volumes of cement paste and w/c ratios ranging from 0.30 to 0.60. Second, the finite element method was used to simulate the diffusion of tritiated water through these microstructures. Effective cement paste diffusivity values for different REVs were obtained by applying Fick’s law. Finally, statistical analysis was used to find the fluctuation in effective diffusivity with cement paste volume, from which the REV was then determined. The conclusion drawn was that the REV for measuring diffusivity in cement paste is 100x100x100 μm3.

    La difusividad del hormigón depende de su microestructura a numerosas escalas, desde nanómetros hasta milímetros, por lo que se precisa de técnicas multiescala para representar este parámetro. Junto con el principio de homogeneización, uno de los métodos multiescala más habituales es el volumen elemental representativo (VER. El objeto de este estudio era establecer un procedimiento que permitiera determinar el VER necesario para calcular la difusividad de la pasta de cemento, basándose en un método numéricoestadístico que consta de tres etapas. Primero, se crearon varias series de microestructuras de pasta de cemento en 3D con HYMOSTRUC3D, un programa que permite crear un modelo de la hidratación y microestructura del cemento. Luego se empleó el método de

  15. Erratum to: “Vortex fermion on the lattice” [Nucl. Phys. B 636 (2002) 264 290

    Science.gov (United States)

    Nagao, Keiichi

    2008-09-01

    In Ref. [H. Neuberger, hep-lat/03030090] Neuberger studied a vortex fermion model with two continuum extra-dimensions, and pointed out that there are no k≠0 zero modes, which is in disagreement with our paper. Since this discrepancy is due to an error in our paper, we give relevant corrections. The main result of our paper that a normalizable zero mode solution appears at the core of the vortex does not change.

  16. Intermittent Bellerophon state in frequency-weighted Kuramoto model

    Science.gov (United States)

    Zhou, Wenchang; Zou, Yong; Zhou, Jie; Liu, Zonghua; Guan, Shuguang

    2016-12-01

    Recently, the Bellerophon state, which is a quantized, time dependent, clustering state, was revealed in globally coupled oscillators [Bi et al., Phys. Rev. Lett. 117, 204101 (2016)]. The most important characteristic is that in such a state, the oscillators split into multiple clusters. Within each cluster, the instantaneous frequencies of the oscillators are not the same, but their average frequencies lock to a constant. In this work, we further characterize an intermittent Bellerophon state in the frequency-weighted Kuramoto model with a biased Lorentzian frequency distribution. It is shown that the evolution of oscillators exhibits periodical intermittency, following a synchronous pattern of bursting in a short period and resting in a long period. This result suggests that the Bellerophon state might be generic in Kuramoto-like models regardless of different arrangements of natural frequencies.

  17. Study of a Model Equation in Detonation Theory

    KAUST Repository

    Faria, Luiz

    2014-04-24

    Here we analyze properties of an equation that we previously proposed to model the dynamics of unstable detonation waves [A. R. Kasimov, L. M. Faria, and R. R. Rosales, Model for shock wave chaos, Phys. Rev. Lett., 110 (2013), 104104]. The equation is ut+ 1/2 (u2-uu (0-, t))x=f (x, u (0-, t)), x > 0, t < 0. It describes a detonation shock at x = 0 with the reaction zone in x > 0. We investigate the nature of the steady-state solutions of this nonlocal hyperbolic balance law, the linear stability of these solutions, and the nonlinear dynamics. We establish the existence of instability followed by a cascade of period-doubling bifurcations leading to chaos. © 2014 Society for Industrial and Applied Mathematics.

  18. Unconventional fermi surface instabilities in the kagome Hubbard model.

    Science.gov (United States)

    Kiesel, Maximilian L; Platt, Christian; Thomale, Ronny

    2013-03-22

    We investigate the competing Fermi surface instabilities in the kagome tight-binding model. Specifically, we consider on-site and short-range Hubbard interactions in the vicinity of van Hove filling of the dispersive kagome bands where the fermiology promotes the joint effect of enlarged density of states and nesting. The sublattice interference mechanism devised by Kiesel and Thomale [Phys. Rev. B 86, 121105 (2012)] allows us to explain the intricate interplay between ferromagnetic fluctuations and other ordering tendencies. On the basis of the functional renormalization group used to obtain an adequate low-energy theory description, we discover finite angular momentum spin and charge density wave order, a twofold degenerate d-wave Pomeranchuk instability, and f-wave superconductivity away from van Hove filling. Together, this makes the kagome Hubbard model the prototypical scenario for several unconventional Fermi surface instabilities.

  19. Cylindrically symmetric cosmological model of the universe in modified gravity

    Science.gov (United States)

    Mishra, B.; Vadrevu, Samhita

    2017-02-01

    In this paper, we have constructed the cosmological models of the universe in a cylindrically symmetric space time in two classes of f(R,T) gravity (Harko et al. in Phys. Rev. D 84:024020, 2011). We have discussed two cases: one in the linear form and the other in the quadratic form of R. The matter is considered to be in the form of perfect fluid. It is observed that in the first case, the pressure and energy density remain the same, which reduces to a Zeldovich fluid. In the second case we have studied the quadratic function of f(R,T) gravity in the form f(R)=λ(R+R2) and f(T)=λ T. In the second case the pressure is in the negative domain and the energy density is in the positive domain, which confirms that the equation of state parameter is negative. The physical properties of the constructed models are studied.

  20. Entanglement in a generalized Jaynes-Cummings model

    Institute of Scientific and Technical Information of China (English)

    Zhang Guo-Feng; Liu Jia

    2007-01-01

    We investigate the pairwise entanglement and global entanglement in a generalized Jaynes-Cummings model,which can be used to realize Greenberger-Horne-Zeilinger (GHZ) entangled state (Zheng S B 2001 Phys. Rev. Lett. 87230404). Our results show that the W-type entangled states cannot be generated based on the model. The dependences of entanglement on Rabi frequency λ and dipole-dipole coupling strength Ω are given. It is found that there exists the quantum phase transition when λ = Ω. For typical experimental data, the critical temperature for pairwise entanglement is on the order of 10-6 K. Based on these results, two strategies that overcome decoherence are proposed.

  1. A coarse-grained DNA model for the prediction of current signals in DNA translocation experiments

    Science.gov (United States)

    Weik, Florian; Kesselheim, Stefan; Holm, Christian

    2016-11-01

    We present an implicit solvent coarse-grained double-stranded DNA (dsDNA) model confined to an infinite cylindrical pore that reproduces the experimentally observed current modulations of a KaCl solution at various concentrations. Our model extends previous coarse-grained and mean-field approaches by incorporating a position dependent friction term on the ions, which Kesselheim et al. [Phys. Rev. Lett. 112, 018101 (2014)] identified as an essential ingredient to correctly reproduce the experimental data of Smeets et al. [Nano Lett. 6, 89 (2006)]. Our approach reduces the computational effort by orders of magnitude compared with all-atom simulations and serves as a promising starting point for modeling the entire translocation process of dsDNA. We achieve a consistent description of the system's electrokinetics by using explicitly parameterized ions, a friction term between the DNA beads and the ions, and a lattice-Boltzmann model for the solvent.

  2. Ferroelectricity in a diatomic Ising chain as investigated by the elastic Ising model

    Institute of Scientific and Technical Information of China (English)

    Guo Yun-Jun; Wang Ke-Feng; Liu Jun-Ming

    2009-01-01

    An elastic Ising model for a one-dimensional diatomic spin chain is proposed to explain the ferroelectricity induced by the collinear magnetic order with a low-excited energy state. A statistical theory based on this model is developed to calculate the electrical and magnetic properties of Ca3CoMnO6, a typical quasi-one-dimensional diatomic spin chain system. The calculated ferroelectric polarization and dielectric susceptibility show a good agreement with recently reported data on Ca3Co2-xMnxO6 (x≈0.96) (Phys. Rev. Lett. 100 047601 (2008)), although the predicted magnetic susceptibility does not coincide well with experiment. We also address the rationality and deficiency of this model by including a first-order correction which improves the consistency between the model and experiment.

  3. Low-lying Photoexcited States of a One-Dimensional Ionic Extended Hubbard Model

    Science.gov (United States)

    Yokoi, Kota; Maeshima, Nobuya; Hino, Ken-ichi

    2017-10-01

    We investigate the properties of low-lying photoexcited states of a one-dimensional (1D) ionic extended Hubbard model at half-filling. Numerical analysis by using the full and Lanczos diagonalization methods shows that, in the ionic phase, there exist low-lying photoexcited states below the charge transfer gap. As a result of comparison with numerical data for the 1D antiferromagnetic (AF) Heisenberg model, it was found that, for a small alternating potential Δ, these low-lying photoexcited states are spin excitations, which is consistent with a previous analytical study [Katsura et al., Phys. Rev. Lett. 103, 177402 (2009)]. As Δ increases, the spectral intensity of the 1D ionic extended Hubbard model rapidly deviates from that of the 1D AF Heisenberg model and it is clarified that this deviation is due to the neutral-ionic domain wall, an elementary excitation near the neutral-ionic transition point.

  4. The high-temperature expansion of the classical Ising model with Sz2 term

    Directory of Open Access Journals (Sweden)

    M.T. Thomaz

    2012-03-01

    Full Text Available We derive the high-temperature expansion of the Helmholtz free energy up to order β17 of the one-dimensional spin-S Ising model, with single-ion anisotropy term, in the presence of a longitudinal magnetic field. We show that the values of some thermodynamical functions for the ferromagnetic models, in the presence of a weak magnetic field, are not small corrections to their values with h=0. This model with S=3 was applied by Kishine et al. [J.-i. Kishine et al., Phys. Rev. B, 2006, 74, 224419] to analyze experimental data of the single-chain magnet [Mn (saltmen]2 [Ni(pac2 (py2] (PF62 for T<40 K. We show that for T<35 K the thermodynamic functions of the large-spin limit model are poor approximations to their analogous spin-3 functions.

  5. Computational studies of competing phases in model Hamiltonians

    Science.gov (United States)

    Jiang, Mi

    superfluid phase. Finally, a newly developed numerical scheme for solving Langevin equations, which eliminates step-size error, is tested in the two-dimensional (2D) classical XY model and proven to be efficient to obtain the Berezinskii-Kosterlitz-Thouless (BKT) transition temperature. We further used the method to study the 2D antiferromagnetic Heisenberg model with an external magnetic field, which belongs to the same universality class as the 2D XY model due to the antiferromagnetic coupling. The BKT-type transition temperature vs magnetic field Tc( B) is obtained. The organization of this dissertation is as follows: In Chap. 1 we introduce the model Hamiltonians studied throughout the dissertation and their basic properties. Chap. 2 illustrates various methodologies utilized. Chap. 3-5 discuss the applications of determinant Quantum Monte Carlo (DQMC) in three different physical problems, which are based on Phys. Rev. B 86, 195117 (2012) and Phys. Rev. B 87, 165101 (2013) respectively. Chap. 6 focuses on the interplay between s-wave superconductivity and spin-dependent disorder via the Bogoliubov-de Gennes mean field theory and is based on New J. Phys. 15, 023023 (2013) and Phys. Rev. B 85, 134506 (2012). Chap. 7 is devoted to the test of a newly developed Langevin scheme and its applications in two-dimensional classical XY model and antiferromagnetic Heisenberg model.

  6. Comment on "Propagation of surface waves on a semi-bounded quantum magnetized collisional plasma" [Phys. Plasmas 20, 122106 (2013)

    Science.gov (United States)

    Moradi, Afshin

    2016-04-01

    In a recent article [Niknam et al., Phys. Plasmas 20, 122106 (2013)], Niknam et al. investigated the propagation of TM surface waves on a semi-bounded quantum magnetized collisional plasma in the Faraday configuration (in this case, the magnetic field is parallel to the both of the plasma surface and direction of propagation). Here, we present a fresh look at the problem and show that TM surface waves cannot propagate on surface of the present system. We find in the Faraday configuration the surface waves acquire both TM and TE components due to the cyclotron motion of electrons. Therefore, the main result of the work by Niknam et al. is incorrect.

  7. Comment on "Surface electromagnetic wave equations in a warm magnetized quantum plasma" [Phys. Plasmas 21, 072114 (2014)

    Science.gov (United States)

    Moradi, Afshin

    2016-07-01

    In a recent article [C. Li et al., Phys. Plasmas 21, 072114 (2014)], Li et al. studied the propagation of surface waves on a magnetized quantum plasma half-space in the Voigt configuration (in this case, the magnetic field is parallel to the surface but is perpendicular to the direction of propagation). Here, we present a fresh look at the problem and obtain a new form of dispersion relation of surface waves of the system. We find that our new dispersion relation does not agree with the result obtained by Li et al.

  8. Comment on "The physics origin of the hierarchy of bodies in space" [J. Appl. Phys. 119, 094901 (2016)

    Science.gov (United States)

    Swartz, C. H.

    2016-09-01

    A recent paper [A. Bejan and R. W. Wagstaff, J. Appl. Phys. 119, 094901 (2016)] concludes that bodies of the same size suspended uniformly in space are in a state of high internal tension. The tension is then relieved by rearrangement of the bodies into a non-uniform distribution of mass. In this Comment, it is shown that the conclusions are based upon calculations which are in error, and that the amount of tension is not in fact decreased by such a rearrangement.

  9. Experimental Plan for EDF Energy Creep Rabbit Graphite Irradiations- Rev. 2 (replaces Rev. 0 ORNL/TM/2013/49).

    Energy Technology Data Exchange (ETDEWEB)

    Burchell, Timothy D [ORNL

    2014-07-01

    The experimental results obtained here will assist in the development and validation of future models of irradiation induced creep of graphite by providing the following data: Inert creep stain data from low to lifetime AGR fluence Inert creep-property data (especially CTE) from low to lifetime AGR fluence Effect of oxidation on creep modulus (by indirect comparison with experiment 1 and direct comparison with experiment 3 NB. Experiment 1 and 3 are not covered here) Data to develop a mechanistic understanding, including oAppropriate creep modulus (including pinning and high dose effects on structure) oInvestigation of CTE-creep strain behavior under inert conditions oInformation on the effect of applied stress/creep strain on crystallite orientation (requires XRD) oEffect of creep strain on micro-porosity (requires tomography & microscopy) This document describes the experimental work planned to meet the requirements of project technical specification [1] and EDF Energy requests for additional Pre-IE work. The PIE work is described in detail in this revision (Section 8 and 9).

  10. Requirement of DDX3 DEAD box RNA helicase for HIV-1 Rev-RRE export function.

    Science.gov (United States)

    Yedavalli, Venkat S R K; Neuveut, Christine; Chi, Ya-Hui; Kleiman, Lawrence; Jeang, Kuan-Teh

    2004-10-29

    A single transcript in its unspliced and spliced forms directs the synthesis of all HIV-1 proteins. Although nuclear export of intron-containing cellular transcripts is restricted in mammalian cells, HIV-1 has evolved the viral Rev protein to overcome this restriction for viral transcripts. Previously, CRM1 was identified as a cellular cofactor for Rev-dependent export of intron-containing HIV-1 RNA. Here, we present evidence that Rev/CRM1 activity utilizes the ATP-dependent DEAD box RNA helicase, DDX3. We show that DDX3 is a nucleo-cytoplasmic shuttling protein, which binds CRM1 and localizes to nuclear membrane pores. Knockdown of DDX3 using either antisense vector or dominant-negative mutants suppressed Rev-RRE-function in the export of incompletely spliced HIV-1 RNAs. Plausibly, DDX3 is the human RNA helicase which functions in the CRM1 RNA export pathway analogously to the postulated role for Dbp5p in yeast mRNA export.

  11. Horns Rev 2 offshore wind farm photo case with wakes observed in 2016

    DEFF Research Database (Denmark)

    Hasager, Charlotte Bay; Nygaard, Nicolai Gayle; Volker, Patrick

    Offshore wind farm wakes were photographed in foggy conditions at Horns Rev 2 on 25 January 2016 at 12:45 UTC (See1). The study examines the atmospheric conditions from satellite images, radiosonde, vertical profiling wind lidar located at the transformer platform and SCADA data. Furthermore...

  12. Multiple roles of Rev3, the catalytic subunit of polzeta in maintaining genome stability in vertebrates

    NARCIS (Netherlands)

    E. Sonoda (Eiichiro); S. Takeda (Shiunichi); T. Okada (Takashi); G.Y. Zhao (Guang); S. Tateishi (Satoshi); K. Araki (Kasumi); M. Yamaizumi (Masaru); T. Yagi (Takashi); N.S. Verkaik (Nicole); D.C. van Gent (Dik); M. Takata (Minoru)

    2003-01-01

    textabstractTranslesion DNA synthesis (TLS) and homologous DNA recombination (HR) are two major postreplicational repair (PRR) pathways. The REV3 gene of Saccharomyces cerevisiae encodes the catalytic subunit of DNA polymerase zeta, which is involved in mutagenic TLS. To investigat

  13. Power deficits due to wind turbine wakes at Horns Rev wind farm

    DEFF Research Database (Denmark)

    Hansen, Kurt Schaldemose; Barthelmie, Rebecca; Jensen, Leo E.

    2010-01-01

    The wind turbine operational charac-teristics, power measurements and the meteorological measurements as 10 minute statistical data from Horns Rev offshore wind farm have been identified, synchronized, quality screened and stored in a common database. A number of flow cases have been identified...

  14. TextRev: A Window into How General and Organic Chemistry Students Use Textbook Resources.

    Science.gov (United States)

    Smith, Bradley D.; Jacobs, Dennis C.

    2003-01-01

    Points out the important use of textbooks and their ancillary resources in lower-division chemistry courses and the scientific misconceptions found in them. Introduces the TextRev Project which is a new resource for data collection and analysis. Investigates how first and second year chemistry students use and value their textbooks and their study…

  15. Regulation of bile acid synthesis by the nuclear receptor Rev-erb alpha

    NARCIS (Netherlands)

    Duez, Helene; Van Der Veen, Jelske N.; Duhem, Christian; Pourcet, Benoit; Touvier, Thierry; Fontaine, Coralie; Derudas, Bruno; Bauge, Eric; Havinga, Rick; Bloks, Vincent W.; Wolters, Henk; Van Der Sluijs, Fjodor H.; Vennstrom, Bjorn; Kuipers, Folkert; Staels, Bart

    2008-01-01

    Background & Aims: Conversion into bile acids represents an important route to remove excess cholesterol from the body. Rev-erb alpha is a nuclear receptor that participates as one of the clock genes in the control of circadian rhythmicity and plays a regulatory role in lipid metabolism and adipogen

  16. Dynamics of a model colloidal suspension from dilute to freezing

    Science.gov (United States)

    Hannam, S. D. W.; Daivis, P. J.; Bryant, G.

    2016-07-01

    Molecular dynamics simulation was used to study a model colloidal suspension at a range of packing fractions from the dilute limit up to the freezing point. This study builds on previous work by the authors which modeled the colloidal particles with a hard core surrounded by a Weeks-Chandler-Anderson potential with modified interaction parameters, and included an explicit solvent. In this work, we study dynamical properties of the model by first calculating the velocity autocorrelation function, the self-diffusion coefficient, and the mutual diffusion coefficient. We also perform detailed calculations of the colloidal particle intermediate scattering function to study the change in dynamics leading up to the freezing point, and to determine whether the current model can be used to interpret light scattering experiments. We then perform a multiexponential analysis on the intermediate scattering function results and find that the data are fitted well by the sum of two exponentials, which is in line with previous analysis of experimental colloidal suspensions. The amplitudes and decay coefficients of the two modes are determined over a large range of wave vectors at packing fractions leading up to the freezing point. We found that the maximum wave vector at which macroscopic diffusive behavior was observed decreased as the packing fraction increased, and a simple extrapolation shows the maximum wave vector going to zero at the melting point. Lastly, the ratio of the two decay coefficients is compared to the scaling law proposed by Segrè and Pusey [Phys. Rev. Lett. 77, 771 (1996), 10.1103/PhysRevLett.77.771]. It was found that the ratio was not constant, but instead was wave vector dependent.

  17. Contact angles in the pseudopotential lattice Boltzmann modeling of wetting.

    Science.gov (United States)

    Li, Qing; Luo, K H; Kang, Q J; Chen, Q

    2014-11-01

    In this paper we investigate the implementation of contact angles in the pseudopotential lattice Boltzmann modeling of wetting at a large density ratio ρ_{L}/ρ_{V}=500. The pseudopotential lattice Boltzmann model [X. Shan and H. Chen, Phys. Rev. E 49, 2941 (1994)10.1103/PhysRevE.49.2941] is a popular mesoscopic model for simulating multiphase flows and interfacial dynamics. In this model the contact angle is usually realized by a fluid-solid interaction. Two widely used fluid-solid interactions, the density-based interaction and the pseudopotential-based interaction, as well as a modified pseudopotential-based interaction formulated in the present paper are numerically investigated and compared in terms of the achievable contact angles, the maximum and the minimum densities, and the spurious currents. It is found that the pseudopotential-based interaction works well for simulating small static (liquid) contact angles θstatic contact angles close to 180^{∘}. Meanwhile, it is found that the proposed modified pseudopotential-based interaction performs better in light of the maximum and the minimum densities and is overall more suitable for simulating large contact angles θ>90^{∘} as compared with the two other types of fluid-solid interactions. Furthermore, the spurious currents are found to be enlarged when the fluid-solid interaction force is introduced. Increasing the kinematic viscosity ratio between the vapor and liquid phases is shown to be capable of reducing the spurious currents caused by the fluid-solid interactions.

  18. Frustrated classical Heisenberg model with biquadratic interactions in a rhombic lattice: exact ground-state phase diagram

    Science.gov (United States)

    Hayden, L. X.; Kaplan, T. A.; Mahanti, S. D.

    2010-03-01

    The model cited has nearest-neighbor (nn) ferromagnetic and nnn Heisenberg interactions plus nn biquadratic interactions. The rhombic symmetry comes from assuming the nnn interaction only between sites on a square lattice connected by (1,1) (not (1,-1)) diagonals, as done for various multiferroic manganitesfootnotetextT. Kimura et al., Phys. Rev. B 68, 060403(R) (2003)^,footnotetextM. Mochizuki and N. Furukawa, J. Phys. Soc. Japan 78, 053704 (2009). The biquadratic interactions replace the much smaller anisotropic terms usually used^2. The ground state problem in the thermodynamic limit is reduced, exactly, to a 3-spin problem, enabled by the LK cluster methodfootnotetextD. H. Lyons and T. A. Kaplan, J. Phys. Chem. Solids 25, 645 (1964), leading to the phase diagram. We find 4 phases: (1) ferromagnetic, (2) general-wave-vector (Q) spiral, (3) up-up-down- down or ``E-type", degenerate with Q=(,), and (4) disordered. The uudd- (,) degeneracy is removed in favor of uudd by a small ferromagnetic nnn interaction connecting sites along the (1,-1) diagonal (such an interaction was in fact found in ref. 1, where the observed uudd state was discussed). It is argued that the present model is probably realistic for these materials.

  19. Offshore wind farms in the local community - a survey at Horns Rev wind farm. Background report; Havvindmoeller i lokalomraedet - en undersoegelse ved Horns Rev havmoellepark. Baggrundsrapport

    Energy Technology Data Exchange (ETDEWEB)

    Kuehn, S.

    2005-07-15

    This report is part of a socio-economic project about offshore wind farms' influence on the local community. The project is part of the monitoring programme in connection with the establishment of the offshore wind farms at Horns Rev and Nysted. The socio-economic project consists of a sociological and an environment-economic project. This report is part of the sociological project which has the purpose of identifying attitudes towards the wind farm before and after the erection with a view to identify possible changes in opinions and reasons for these changes. (BA)

  20. Numerical evidence for a chiral spin liquid in the XXZ antiferromagnetic Heisenberg model on the kagome lattice at m =2/3 magnetization

    Science.gov (United States)

    Kumar, Krishna; Changlani, Hitesh J.; Clark, Bryan K.; Fradkin, Eduardo

    2016-10-01

    We perform an exact-diagonalization study of the spin-1/2 XXZ Heisenberg antiferromagnet on the kagome lattice at finite magnetization m =2/3 with an emphasis on the X Y point (Jz=0 ) and in the presence of a small chiral term. Recent analytic work by Kumar et al. [K. Kumar, K. Sun, and E. Fradkin, Phys. Rev. B 90, 174409 (2014), 10.1103/PhysRevB.90.174409] on the same model, using a newly developed flux attachment transformation, predicts a plateau at this value of the magnetization described by a chiral spin liquid (CSL) with a spin Hall conductance of σx y=1/2 . Such a state is topological in nature, has a ground-state degeneracy, and exhibits fractional excitations. We analyze the degeneracy structure in the low-energy manifold, identify the candidate topological states, and use them to compute the modular matrices and Chern numbers, all of which strongly agree with expected theoretical behavior for the σx y=1/2 CSL. In the limit of zero chirality, we find on most (not all) clusters that the topological invariants are still those of a CSL.

  1. Analysis of spatial correlations in a model two-dimensional liquid through eigenvalues and eigenvectors of atomic-level stress matrices.

    Science.gov (United States)

    Levashov, V A; Stepanov, M G

    2016-01-01

    Considerations of local atomic-level stresses associated with each atom represent a particular approach to address structures of disordered materials at the atomic level. We studied structural correlations in a two-dimensional model liquid using molecular dynamics simulations in the following way. We diagonalized the atomic-level stress tensor of every atom and investigated correlations between the eigenvalues and orientations of the eigenvectors of different atoms as a function of distance between them. It is demonstrated that the suggested approach can be used to characterize structural correlations in disordered materials. In particular, we found that changes in the stress correlation functions on decrease of temperature are the most pronounced for the pairs of atoms with separation distance that corresponds to the first minimum in the pair density function. We also show that the angular dependencies of the stress correlation functions previously reported by Wu et al. [Phys. Rev. E 91, 032301 (2015)10.1103/PhysRevE.91.032301] do not represent the anisotropic Eshelby's stress fields, as it is suggested, but originate in the rotational properties of the stress tensors.

  2. Hard bottom substrate monitoring Horns Rev offshore wind farm. Annual status report 2003

    Energy Technology Data Exchange (ETDEWEB)

    Leonhard, S.B.; Pedersen, John

    2004-05-15

    Elsam and Eltra built the offshore demonstration wind farm at Horns Rev in the North Sea. Elsam is the owner and is responsible for the operation of the wind farm. Eltra is responsible for the connection of the wind farm to the national onshore grid. In the summer months of 2002, Elsam constructed the world's largest offshore wind farm off the Danish west coast. The wind farm is sited 14-20 km into the North Sea, west of Blaevands Huk. The first wind turbine was erected in May 2002 and the last wind turbine tower of a total of 80 was in place by August 2002. The construction work was completed with the last connecting cables sluiced down in September 2002. All the wind turbines were in production by December 2002. The expected impact of the wind farm will primarily be an alternation of habitats due to the introduction of hard bottom substrates as wind turbine towers and scour protections. A continuous development in the epifouling communities will be expected together with an introduction of new or alien species in the area. The indigenous benthic community in the area of Horns Rev can be characterised by infauna species belonging to the Goniadella-Spisula community. This community is typical of sandbanks in the North Sea area, although communities in such areas are very variable and site-specific. Character species used as indicators for environmental changes in the Horns Rev area are the bristle worms Goniadella bobretzkii, Ophelia borealis, Psione remota and Orbinia sertulata and the mussels Goodallia triangularis and Spisula solida. In connection with the implementation of the monitoring programme concerning the ecological impact of the introduction of hard substrate related to the Horns Rev Wind Farm, surveys on hard bottom substrate was conducted in March 2003 and in September 2003. This report describes the first year results of surveys on hard substrate after the completion of the offshore wind farm at Horns Rev. (au)

  3. Peptides derived from HIV-1 integrase that bind Rev stimulate viral genome integration.

    Directory of Open Access Journals (Sweden)

    Aviad Levin

    Full Text Available BACKGROUND: The human immunodeficiency virus type 1 (HIV-1 integrase protein (IN, catalyzes the integration of viral DNA into the host cell genome. IN catalyzes the first step of the integration process, namely the 3'-end processing in which IN removes a pGT dinucleotide from the 3' end of each viral long terminal repeat (LTR. Following nuclear import of the viral preintegration complex, the host chromosomal DNA becomes accessible to the viral cDNA and the second step of the integration process, namely the strand-transfer step takes place. This ordered sequence of events, centered on integration, is mandatory for HIV replication. METHODOLOGY/PRINCIPAL FINDINGS: Using an integrase peptide library, we selected two peptides, designated INr-1 and INr-2, which interact with the Rev protein and probably mediate the Rev-integrase interaction. Using an in-vitro assay system, we show that INr-1 and INr-2 are able to abrogate the inhibitory effects exerted by Rev and Rev-derived peptides on integrase activity. Both INr-1 and INr-2 were found to be cell-permeable and nontoxic, allowing a study of their effect in HIV-1-infected cultured cells. Interestingly, both INr peptides stimulated virus infectivity as estimated by production of the viral P24 protein, as well as by determination of the appearance of newly formed virus particles. Furthermore, kinetics studies revealed that the cell-permeable INr peptides enhance the integration process, as was indeed confirmed by direct determination of viral DNA integration by real-time PCR. CONCLUSIONS/SIGNIFICANCE: The results of the present study raise the possibility that in HIV-infected cells, the Rev protein may be involved in the integration of proviral DNA by controlling/regulating the activity of the integrase. Release from such inhibition leads to stimulation of IN activity and multiple viral DNA integration events.

  4. Lasers (Rev.)

    Energy Technology Data Exchange (ETDEWEB)

    Hellman, Hal

    1969-01-01

    A laser is an instrument that produces an enormously intense pencil-thin beam of light. In this booklet we shall learn what there is about the laser that gives it so much promise. We shall investigate what it is, how it works, and the different kinds of lasers there are.

  5. Computers (Rev.)

    Energy Technology Data Exchange (ETDEWEB)

    Corliss, William R

    1967-01-01

    This booklet relates how wires, transistors, and human ingenuity are combined to produce machines that surpass all the calculating prodigies that ever lived in speed, accuracy, and stamina, though perhaps not in the matter of mystery.

  6. Computers (Rev.)

    Energy Technology Data Exchange (ETDEWEB)

    Corliss, William R

    1967-01-01

    This booklet relates how wires, transistors, and human ingenuity are combined to produce machines that surpass all the calculating prodigies that ever lived in speed, accuracy, and stamina, though perhaps not in the matter of mystery.

  7. A cell-penetrating antibody fragment against HIV-1 Rev has high antiviral activity: characterization of the paratope.

    Science.gov (United States)

    Zhuang, Xiaolei; Stahl, Stephen J; Watts, Norman R; DiMattia, Michael A; Steven, Alasdair C; Wingfield, Paul T

    2014-07-18

    The HIV-1 protein Rev oligomerizes on viral transcripts and directs their nuclear export. Previously, a Fab against Rev generated by phage display was used to crystallize and solve the structure of the Rev oligomerization domain. Here we have investigated the capability of this Fab to block Rev oligomerization and inhibit HIV-1 replication. The Fab itself did not have antiviral activity, but when a Tat-derived cell-penetrating peptide was appended, the resulting molecule (FabRev1-Tat) was strongly inhibitory of three different CCR5-tropic HIV-1 isolates (IC50 = 0.09-0.44 μg/ml), as assessed by suppression of reverse transcriptase activity in infected peripheral blood mononuclear cells, and had low cell toxicity (TC50 > 100 μg/ml). FabRev1-Tat was taken up by both peripheral blood mononuclear and HEK293T cells, appearing in both the cytoplasm and nucleus, as shown by immunofluorescence confocal laser scanning microscopy. Computational alanine scanning was used to identify key residues in the complementarity-determining regions to guide mutagenesis experiments. Residues in the light chain CDR3 (LCDR3) were assessed to be important. Residues in LCDR3 were mutated, and LCDR3-Tyr(92) was found to be critical for binding to Rev, as judged by surface plasmon resonance and electron microscopy. Peptides corresponding to all six CDR regions were synthesized and tested for Rev binding. None of the linear peptides had significant affinity for Rev, but four of the amide-cyclic forms did. Especially cyclic-LCDR3 (LGGYPAASYRTA) had high affinity for Rev and was able to effectively depolymerize Rev filaments, as shown by both surface plasmon resonance and electron microscopy.

  8. Aging and percolation dynamics in a Non-Poissonian temporal network model

    CERN Document Server

    Moinet, Antoine; Pastor-Satorras, Romualdo

    2016-01-01

    We present an exhaustive mathematical analysis of the recently proposed Non-Poissonian Ac- tivity Driven (NoPAD) model [Moinet et al. Phys. Rev. Lett., 114 (2015)], a temporal network model incorporating the empirically observed bursty nature of social interactions. We focus on the aging effects emerging from the Non-Poissonian dynamics of link activation, and on their effects on the topological properties of time-integrated networks, such as the degree distribution. Analytic expressions for the degree distribution of integrated networks as a function of time are derived, ex- ploring both limits of vanishing and strong aging. We also address the percolation process occurring on these temporal networks, by computing the threshold for the emergence of a giant connected component, highlighting the aging dependence. Our analytic predictions are checked by means of extensive numerical simulations of the NoPAD model.

  9. Bianchi type string cosmological models in f(R,T) gravity

    Science.gov (United States)

    Sahoo, P. K.; Mishra, B.; Sahoo, Parbati; Pacif, S. K. J.

    2016-09-01

    In this work we have studied Bianchi-III and - VI 0 cosmological models with string fluid source in f( R, T) gravity (T. Harko et al., Phys. Rev. D 84, 024020 (2011)), where R is the Ricci scalar and T the trace of the stress energy-momentum tensor in the context of late time accelerating expansion of the universe as suggested by the present observations. The exact solutions of the field equations are obtained by using a time-varying deceleration parameter. The universe is anisotropic and free from initial singularity. Our model initially shows acceleration for a certain period of time and then decelerates consequently. Several dynamical and physical behaviors of the model are also discussed in detail.

  10. Lattice Boltzmann modeling of self-propelled Leidenfrost droplets on ratchet surfaces

    CERN Document Server

    Li, Q; Francois, M M; Hu, A J

    2015-01-01

    In this paper, the self-propelled motion of Leidenfrost droplets on ratchet surfaces is numerically investigated with a thermal multiphase lattice Boltzmann model with liquid-vapor phase change. The capability of the model for simulating evaporation is validated via the D2 law. Using the model, we first study the performances of Leidenfrost droplets on horizontal ratchet surfaces. It is numerically shown that the motion of self-propelled Leidenfrost droplets on ratchet surfaces is owing to the asymmetry of the ratchets and the vapor flows beneath the droplets. It is found that the Leidenfrost droplets move in the direction toward the slowly inclined side from the ratchet peaks, which agrees with the direction of droplet motion in experiments [Linke et al., Phys. Rev. Lett., 2006, 96, 154502]. Moreover, the influences of the ratchet aspect ratio are investigated. For the considered ratchet surfaces, a critical value of the ratchet aspect ratio is approximately found, which corresponds to the maximum droplet mo...

  11. Coupled map car-following model and its delayed-feedback control.

    Science.gov (United States)

    Konishi, K; Kokame, H; Hirata, K

    1999-10-01

    This paper proposes a coupled map car-following traffic model, which describes a dynamical behavior of a group of road vehicles running in a single lane without overtaking. This model consists of a lead vehicle and following vehicles, which have a piecewise linear optimal velocity function. When the lead-vehicle speed is varied, we can observe a traffic jam in the group of the vehicles. We derive a condition under which the traffic jam never occurs in our model. Furthermore, in order to suppress the traffic jam, for each vehicle we use a dynamic version of decentralized delayed-feedback control proposed in [Konishi, Hirai, and Kokame, Phys. Rev. E 58, 3055 (1998)], and provide a systematic procedure for designing the controller.

  12. Exact ground-state phase diagrams for the spin-3/2 Blume Emery Griffiths model

    Science.gov (United States)

    Canko, Osman; Deviren, Bayram; Keskin, Mustafa

    2008-05-01

    We have calculated the exact ground-state phase diagrams of the spin-3/2 Ising model using the method that was proposed and applied to the spin-1 Ising model by Dublenych (2005 Phys. Rev. B 71 012411). The calculated, exact ground-state phase diagrams on the diatomic and triangular lattices with the nearest-neighbor (NN) interaction have been presented in this paper. We have obtained seven and 15 topologically different ground-state phase diagrams for J>0 and Jnon-uniform phases. We have also constructed the exact ground-state phase diagrams of the model on the triangular lattice and found 20 and 59 fundamental phase diagrams for J>0 and J<0, respectively, the conditions for the existence of uniform and intermediate phases have also been found.

  13. Implementation of a simple model for linear and nonlinear mixing at unstable fluid interfaces in hydrodynamics codes

    Energy Technology Data Exchange (ETDEWEB)

    Ramshaw, J D

    2000-10-01

    A simple model was recently described for predicting the time evolution of the width of the mixing layer at an unstable fluid interface [J. D. Ramshaw, Phys. Rev. E 58, 5834 (1998); ibid. 61, 5339 (2000)]. The ordinary differential equations of this model have been heuristically generalized into partial differential equations suitable for implementation in multicomponent hydrodynamics codes. The central ingredient in this generalization is a nun-diffusional expression for the species mass fluxes. These fluxes describe the relative motion of the species, and thereby determine the local mixing rate and spatial distribution of mixed fluid as a function of time. The generalized model has been implemented in a two-dimensional hydrodynamics code. The model equations and implementation procedure are summarized, and comparisons with experimental mixing data are presented.

  14. Scaling in erosion of landscapes: renormalization group analysis of a model with turbulent mixing

    Science.gov (United States)

    Antonov, N. V.; Kakin, P. I.

    2017-02-01

    The model of landscape erosion, introduced in (1998 Phys. Rev. Lett. 80 4349, 1998 J. Stat. Phys. 93 477) and modified in (2016 Theor. Math. Phys. in press (arXiv:1602.00432)), is advected by anisotropic velocity field. The field is Gaussian with vanishing correlation time and the pair correlation function of the form \\propto δ ≤ft(t-{{t}\\prime}\\right)/k\\botd-1+ξ , where {{k}\\bot}=|{{\\mathbf{k}}\\bot}| and {{\\mathbf{k}}\\bot} is the component of the wave vector, perpendicular to a certain preferred direction—the d-dimensional generalization of the ensemble introduced by Avellaneda and Majda (1990 Commun. Math. Phys. 131 381). Analogous to the case without advection, the model is multiplicatively renormalizable and has infinitely many coupling constants. The one-loop counterterm is derived in a closed form in terms of the certain function V(h), entering the original stochastic equation, and its derivatives with respect to the height field h≤ft(t,\\mathbf{x}\\right) . The full infinite set of the one-loop renormalization constants, β-functions and anomalous dimensions is obtained from the Taylor expansion of the counter-term. Instead of a two-dimensional surface of fixed points there are two such surfaces; they are likely to contain infrared attractive region(s). If that is the case, the model exhibits scaling behaviour in the infrared range. The corresponding critical exponents are non-universal because they depend on the coordinates of the fixed points on the surface; they also satisfy certain universal exact relation.

  15. SIVsm Tat, Rev, and Nef1: functional characteristics of r-GV internalization on isotypes, cytokines, and intracellular degradation

    Directory of Open Access Journals (Sweden)

    Stuart Elizabeth S

    2010-07-01

    Full Text Available Abstract Background Recombinant gas vesicles (r-GV from Halobacterium sp. strain SD109 expressing cassettes with different SIVsm inserts, have potential utility as an effective antigen display system for immunogen testing in vivo and for initial epitope assessments in vitro. Previous mouse model studies demonstrated immunization with r-GV expressing selected exogenous sequences elicited a prolonged immune response. Here we tested segments from three SIVsm genes (tat, rev, and nef each surface displayed by r-GV. As with HIV, for SIVsm the proteins encoded by tat, rev and nef respectively serve critical and diverse functions: effects on efficient viral RNA polymerase II transcription, regulation of viral gene expression and effects on specific signaling functions through the assembly of multiprotein complexes. Humoral responses to r-GVTat, Rev or Nef1 elicited in vivo, associated changes in selected cell cytokine production following r-GV internalization, and the capacity of J774A.1 macrophage cells to degrade these internalized display/delivery particles in vitro were examined. Results The in vivo studies involving r-GV immunizations and in vitro studies of r-GV uptake by J774A.1 macrophages demonstrated: (i tests for antibody isotypes in immunized mice sera showed activation and re-stimulation of memory B cells, (ii during long term immune response to the epitopes, primarily the IgG1 isotype was produced, (iii in vitro, macrophage degradation of r-GV containing different SIVsm inserts occurred over a period of days resulting in an inherent slow breakdown and degradation of the SIVsm peptide inserts, (iv vesicle specific GvpC, a larger protein, degraded more slowly than the recombinant peptide inserts and (v in vitro uptake and degradation of the r-GV populations tested was associated with SIVsm insert specific patterns for cytokines IL-10, IL-12 and IL-18. Conclusions Together these findings provide new information underscoring r-GV potential

  16. 75 FR 32493 - NUREG-0654/FEMA-REP-, Rev. 1, Supplement 3, Guidance for Protective Action Recommendations for...

    Science.gov (United States)

    2010-06-08

    ... SECURITY Federal Emergency Management Agency NUREG-0654/FEMA-REP-, Rev. 1, Supplement 3, Guidance for... be held to discuss the proposed Supplement 3 to NUREG-0654/FEMA-REP-1, Rev.1, Guidance for Protective Action Recommendations for General Emergencies (NUREG Supp 3). NUREG Supp 3 addresses onsite and...

  17. 48 CFR 53.301-1415 - SF 1415 (Rev. 7/93) Consent of Surety and Increase of Penalty.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false SF 1415 (Rev. 7/93) Consent of Surety and Increase of Penalty. 53.301-1415 Section 53.301-1415 Federal Acquisition Regulations...-1415 SF 1415 (Rev. 7/93) Consent of Surety and Increase of Penalty. EC01MY91.102...

  18. 78 FR 63964 - Request for Comments on Draft NIST Interagency Report (NISTIR) 7628 Rev. 1, Guidelines for Smart...

    Science.gov (United States)

    2013-10-25

    ... (NISTIR) 7628 Rev. 1, Guidelines for Smart Grid Cyber Security AGENCY: National Institute of Standards and... Smart Grid Cyber Security. Draft NISTIR 7628 Rev. 1 was completed by the NIST-led Smart Grid Cybersecurity Committee (formerly the Cyber Security Working Group) of the Smart Grid Interoperability...

  19. Transition times in the Landau-Zener model

    CERN Document Server

    Vitanov, N V

    1999-01-01

    This paper presents analytic formulas for various transition times in the Landau-Zener model. Considerable differences are found between the transition times in the diabatic and adiabatic bases, and between the jump time (the time for which the transition probability rises to the region of its asymptotic value) and the relaxation time (the characteristic damping time of the oscillations which appear in the transition probability after the crossing). These transition times have been calculated by using the exact values of the transition probabilities and their derivatives at the crossing point and approximations to the time evolutions of the transition probabilities in the diabatic basis, derived earlier \\protect{[}N. V. Vitanov and B. M. Garraway, Phys. Rev. A {\\bf 53}, 4288 (1996)\\protect{]}, and similar results in the adiabatic basis, derived in the present paper.

  20. Identification of Brucella melitensis Rev.1 vaccine-strain genetic markers: Towards understanding the molecular mechanism behind virulence attenuation.

    Science.gov (United States)

    Issa, Mohammad Nouh; Ashhab, Yaqoub

    2016-09-22

    Brucella melitensis Rev.1 is an avirulent strain that is widely used as a live vaccine to control brucellosis in small ruminants. Although an assembled draft version of Rev.1 genome has been available since 2009, this genome has not been investigated to characterize this important vaccine. In the present work, we used the draft genome of Rev.1 to perform a thorough genomic comparison and sequence analysis to identify and characterize the panel of its unique genetic markers. The draft genome of Rev.1 was compared with genome sequences of 36 different Brucella melitensis strains from the Brucella project of the Broad Institute of MIT and Harvard. The comparative analyses revealed 32 genetic alterations (30 SNPs, 1 single-bp insertion and 1 single-bp deletion) that are exclusively present in the Rev.1 genome. In silico analyses showed that 9 out of the 17 non-synonymous mutations are deleterious. Three ABC transporters are among the disrupted genes that can be linked to virulence attenuation. Out of the 32 mutations, 11 Rev.1 specific markers were selected to test their potential to discriminate Rev.1 using a bi-directional allele-specific PCR assay. Six markers were able to distinguish between Rev.1 and a set of control strains. We succeeded in identifying a panel of 32 genome-specific markers of the B. melitensis Rev.1 vaccine strain. Extensive in silico analysis showed that a considerable number of these mutations could severely affect the function of the associated genes. In addition, some of the discovered markers were able to discriminate Rev.1 strain from a group of control strains using practical PCR tests that can be applied in resource-limited settings.

  1. Administrative Cicular No. 31 (Rev. 2) - International indemnity and non-resident allowance

    CERN Multimedia

    Department Head Office - HR Department

    2016-01-01

    Administrative Circular No. 31 (Rev. 2) entitled "International indemnity and non-resident allowance", approved by the Director-General following discussion in the Standing Concertation Committee meeting on 23 June 2016, will be available on 1st September 2016 via the following link: https://cds.cern.ch/record/2208547.   This revised circular cancels and replaces Administrative Circular No. 31 (Rev. 1) also entitled "International indemnity and non-resident allowance" of October 2007. The main changes reflect the decision taken in the framework of the five-yearly review to extend eligibility for international indemnity to all staff members, as well to introduce a distinction between current staff members and those recruited as from 1st September 2016. For the latter, the international indemnity will be calculated as a percentage of the minimum salary of the grade into which they are recruited; the amount granted to the former will not change, and is now expressed ...

  2. The "effects" of Rev-1 vaccination of sheep and goats on human brucellosis in Greece.

    Science.gov (United States)

    Minas, A; Minas, M; Stournara, A; Tselepidis, S

    2004-06-10

    Vaccination of young animals (3-6-month-old sheep and goats) with Rev-1 vaccine for 15 years in Greece, importantly decreased the abortions in sheep and goats as well as the incidence of brucellosis in humans. After the stop of vaccination in 1994, all over Greece, the prevalence of brucellosis in animals and the incidence in humans quickly increased. It was a positive rank correlation (0.90) among these variables. Once an emergency mass-vaccination programme of young and adult animals with Rev-1 vaccine was started in 1998, the human incidence again decreased. The association of the vaccination coverage of animals and incidence of brucellosis in humans was not linear; the decrease in human brucellosis incidence was observed when the vaccination coverage of animals was >30%.

  3. Administrative Circular No. 11 (Rev. 3) - Categories of members of the personnel

    CERN Multimedia

    2014-01-01

    Administrative Circular No. 11 (Rev. 3) entitled “Categories of members of the personnel”, approved by the Director-General following discussion at the Standing Concertation Committee meeting of 3 July 2014 and entering into force on 1 September 2014, is available on the intranet site of the Human Resources Department.   This circular is applicable to all members of the personnel. It cancels and replaces Administrative Circular No. 11 (Rev. 2) entitled “Categories of members of the personnel” of January 2013. The circular was revised in order to include a minor adjustment of the determination of required period of break in the payment of subsistence allowance to certain categories of associated members of the personnel (taking account of possible technical means of control). Furthermore, the possibility of traineeships of long duration was restricted to cases in which the traineeship is awarded pursuant to an agreement between CERN and a...

  4. Administrative Circular No. 13 (Rev. 3) - Guarantees for representatives of the personnel

    CERN Multimedia

    2014-01-01

    Administrative Circular No. 13 (Rev. 3) entitled “Guarantees for representatives of the personnel”, approved by the Director-General following discussion at the Standing Concertation Committee meeting of 5 December 2013 and entering into force on 1 January 2014, is available on the intranet site of the Human Resources Department (see here).   This circular is applicable to all members of the personnel. It cancels and replaces Administrative Circular No. 13 (Rev. 2) entitled “Guarantees for members of the personnel holding representative office” of November 1992. The circular was revised in order to adapt the time given to the representatives of the personnel to perform their elective mandate and to ensure more transparency in their activities, by indicating, inter alia, the percentage of time worked in the framework of their mandate, as well as the training, activities and ensuing results. Department Head Office HR Department

  5. A Circular Motion Activity with Hot Wheels® Rev-Ups

    Science.gov (United States)

    Wagner, Glenn

    2009-02-01

    Hot Wheels® Rev-Ups provide a pedagogically engaging and inexpensive culminating activity for the application of circular motion with constant speed in introductory mechanics. The introductory Rev-Up, shown in Fig. 1, consists of a very durable car with two strong magnets built into the front and back of the car. The track is a piece of flexible plastic with a built-in metallic strip through its center that can then be formed into a circle. Pushing the car forward several times on a flat surface allows the car to move in a vertical circle when placed inside the track. What makes this toy attractive is that the gearing system allows the car to move at a relatively constant speed for about three to five seconds before slowing down appreciably.

  6. Portable Tester Friction (PFT). Mesures du coefficient de frottement dynamique de revêtements de sol

    OpenAIRE

    Marchal, P.; Jacques, M.

    2014-01-01

    Le Portable Tester Friction (PFT) est un appareil destiné à mesurer le coefficient de frottement dynamique d’un revêtement de sol en laboratoire et sur site. Ce document décrit le protocole de mesure avec le PFT et les résultats de mesures effectuées sur un panel de quinze revêtements de sol de caractéristiques différentes (matériaux, états de surface) réalisées en présence de deux polluants (huile et solution d’eau). Le PFT présente une très bonne sensibilité et une très bonne répétabilité. ...

  7. RevTrans: multiple alignment of coding DNA from aligned amino acid sequences

    DEFF Research Database (Denmark)

    Wernersson, Rasmus; Pedersen, Anders Gorm

    2003-01-01

    The simple fact that proteins are built from 20 amino acids while DNA only contains four different bases, means that the 'signal-to-noise ratio' in protein sequence alignments is much better than in alignments of DNA. Besides this information-theoretical advantage, protein alignments also benefit...... proteins. It is therefore preferable to align coding DNA at the amino acid level and it is for this purpose we have constructed the program RevTrans. RevTrans constructs a multiple DNA alignment by: (i) translating the DNA; (ii) aligning the resulting peptide sequences; and (iii) building a multiple DNA...... alignment by 'reverse translation' of the aligned protein sequences. In the resulting DNA alignment, gaps occur in groups of three corresponding to entire codons, and analogous codon positions are therefore always lined up. These features are useful when constructing multiple DNA alignments for phylogenetic...

  8. Administrative circular No. 20 (Rev. 2) – Use of private vehicules for journeys on official duty

    CERN Multimedia

    HR Department

    2011-01-01

    Administrative Circular No. 20 (Rev. 2) entitled "Use of private vehicles for journeys on official duty", adopted following discussion in the Standing Concertation Committee meeting of 21 September 2010 and entering into force on 1 January 2011, is available on the intranet site of the Human Resources Department: http://cern.ch/hr-docs/admincirc/admincirc.asp It cancels and replaces Administrative Circular No. 20 (Rev. 1) entitled "Use of private vehicles on official duty" of April 1993. This new version introduces, in particular, the payment of a kilometer allowance in case of emergency during standby duty or when on call and a simplified calculation of the allowance for journeys between sites. This circular also clarifies the type of permitted private vehicles. Department Head Office  

  9. Administrative circular n°23 (Rev. 3) – Special working hours

    CERN Multimedia

    2013-01-01

    Administrative Circular No. 23 (Rev. 3) entitled “Special working hours”, approved by the Director-General following discussion at the Standing Concertation Committee meeting of 11 October 2012 and entering into force on 1 January 2013, is available on the intranet site of the Human Resources Department.   This circular is applicable to staff members and fellows. It cancels and replaces Administrative Circular No. 23 (Rev. 2) entitled “Special working hours” of December 2008. Paragraph 6 a) of Annex II of this circular was revised following the modification of Article III 1.04 of the Staff Regulations approved by Council on 14 December 2012. The modification serves to adapt the minimum rest time to the fact that, in case of rapidly alternating shifts, a maximum of seven consecutive shifts may be performed. Department Head Office HR Department

  10. Administrative circular n°11 (REV. 2) – Categories of members of the personnel

    CERN Multimedia

    2012-01-01

    Administrative Circular No. 11 (Rev. 2) entitled “Categories of members of the personnel”, approved by the Director-General following discussion at the Standing Concertation Committee meeting of 11 May 2012 and entering into force on 1 January 2013, is available on the intranet site of the Human Resources Department. This circular is applicable to all members of the personnel. It cancels and replaces Administrative Circular No. 11 (Rev. 1) entitled “Categories of members of the personnel” of January 1997 as regards all contracts of members of the personnel issued on or after 1 January 2013. The circular was revised in order to take into account developments since the last revision of the categories of personnel in 1997 as well as the needs of the Organization and collaborating institutes. In particular, it introduces a new system for distinguishing categories of associated members of the personnel, namely with regard to the purpo...

  11. RevPAR、收益管理与收益管理经理

    Institute of Scientific and Technical Information of China (English)

    王大悟

    2013-01-01

    一、RevPAR这是酒店业熟悉的指标,即每间可供出租客房的实际平均房价,以客房门市价与出租率的乘积得出。这个指标至少考量了出租率与房价两个重要因素的组合,单纯出租率和房价并不能科学反映酒店的经营业绩。因此到目前为止,RevPAR依然是衡量与比较酒店经营状况的一个标准。

  12. Effects on birds of an offshore wind park at Horns Rev: Environmental impact assessment

    Energy Technology Data Exchange (ETDEWEB)

    Noer, H.; Kjaer Christensen, T.; Clausager, I.; Krag Petersen, I. [DMU, Dept. of Coastal Zone Ecology (Denmark)

    2000-07-01

    This report presents the technical background to the ornithological environmental impact assessment for the construction of an offshore windpark at Horns Rev, 14 km west-south-west of Blaevandshuk, Denmark. Construction of the park is planned to commence in 2001. The park will consist of c. 80 wind turbines, each of at least 1.8 MW, and cover an area of 27.5 km{sup 2} (including the 200 m exclusion zone around the park). (au)

  13. Hard bottom substrate monitoring Horns Rev offshore wind farm. Annual status report. 2004

    Energy Technology Data Exchange (ETDEWEB)

    Leonhard, S.B.; Pedersen, John

    2005-05-15

    Elsam and Eltra have built the offshore demonstration wind farm at Horns Rev in the North Sea. Elsam is the owner and is responsible for the operation of the wind farm. Eltra is responsible for the connection of the wind farm to the national onshore grid. In the summer months of 2002, Elsam constructed the world's largest offshore wind farm at the Danish west coast. The wind farm is located 14-20 km into the North Sea, west of Blaevands Huk. The first wind turbine foundation was in place in March 2002 and the last mono-pile was in place in August 2002 for a total of 80. The construction work was completed with the last connecting cables sluiced down in September 2002. All the wind turbines were in production in December 2002. The expected impact from the wind farm will primarily be an alternation of habitats due to the introduction of hard bottom substrates as wind mono-piles and scour protections. A continuous development in the epifouling communities will be expected together with an introduction of new or alien species in the area. The indigenous benthic community in the area of Horn Rev can be characterised by infauna species belonging to the Goniadella-Spisula community. This community is typical of sandbanks in the North Sea area, although communities in such areas are very variable and site specific. Character species used as indicators for environmental changes in the Horns Rev area are the bristle worms Goniadella bobretzkii, Ophelia borealis, Psione remota and Orbinia sertulata and the mussels Goodallia triangularis and Spisula solida. In connection with the implementation of the monitoring programme concerning the ecological impact of the introduction of hard substrate related to the Horns Rev Wind Farm, surveys on hard bottom substrates were initialised in March 2003 with monitoring conducted in September 2003 and March and September 2004. This report describes the results from surveys on hard substrates in 2004. (au)

  14. International AIDS Society conference update. Compound targeting Rev protein promising. Orphaned approach still looking for home.

    Science.gov (United States)

    2005-09-01

    While clinicians and HIV/AIDS patients anxiously watch the trend of the virus developing resistance to multiple antiretroviral therapies, the question remains whether new drug research will continue to save the day. Some suggest there will need to be multiple new classes of antiretroviral drugs developed in order to stretch further the life span of longtime HIV patients. One potential new class would target the Rev protein, an approach that has received very little attention from the research and pharmaceutical communities.

  15. Uniform asymptotic approximation of diffusion to a small target: Generalized reaction models

    Science.gov (United States)

    Isaacson, Samuel A.; Mauro, Ava J.; Newby, Jay

    2016-10-01

    The diffusion of a reactant to a binding target plays a key role in many biological processes. The reaction radius at which the reactant and target may interact is often a small parameter relative to the diameter of the domain in which the reactant diffuses. We develop uniform in time asymptotic expansions in the reaction radius of the full solution to the corresponding diffusion equations for two separate reactant-target interaction mechanisms: the Doi or volume reactivity model and the Smoluchowski-Collins-Kimball partial-absorption surface reactivity model. In the former, the reactant and target react with a fixed probability per unit time when within a specified separation. In the latter, upon reaching a fixed separation, they probabilistically react or the reactant reflects away from the target. Expansions of the solution to each model are constructed by projecting out the contribution of the first eigenvalue and eigenfunction to the solution of the diffusion equation and then developing matched asymptotic expansions in Laplace-transform space. Our approach offers an equivalent, but alternative, method to the pseudopotential approach we previously employed [Isaacson and Newby, Phys. Rev. E 88, 012820 (2013), 10.1103/PhysRevE.88.012820] for the simpler Smoluchowski pure-absorption reaction mechanism. We find that the resulting asymptotic expansions of the diffusion equation solutions are identical with the exception of one parameter: the diffusion-limited reaction rates of the Doi and partial-absorption models. This demonstrates that for biological systems in which the reaction radius is a small parameter, properly calibrated Doi and partial-absorption models may be functionally equivalent.

  16. 生物钟基因Rev-erb-α缺失导致雌鼠生理周期延长%Circadian clock gene Rev-erb-α deficiency prolongs female estrous cyclicity

    Institute of Scientific and Technical Information of China (English)

    张芹; 董珍; 吴曦; 颜洁; 高基民

    2013-01-01

    在哺乳动物中,生物节律与生殖生理和生殖内分泌密切相关,流行病学研究显示长期倒时差的女性表现出生殖力低下和不良妊娠的概率更高,但是人们对生物节律影响生殖的机制了解还很少.本研究旨在以时钟基因Rev-erb-α敲除型(Reverb-α-/-)雌性小鼠为模型初步探索生物节律对生殖的影响.将Rev-erb-α-/-和野生型(Rev-erb-α+/+)小鼠与C57BL/6J小鼠交配观察生殖力变化,用苏木精-伊红(HE)染色法观察卵巢组织变化,将Rev-erb-α+/+与Rev-erb-α-/-雌性小鼠分别与C57BL/6J雄性小鼠交配后比较见栓后1.5 d统计的胚胎数量,用阴道涂片结合周期图和周期谱观察小鼠生理周期变化.结果显示,Rev-erb-α-/-雌性小鼠与C57BL/6J雄鼠交配是不生育的,并且Rev-erb-α-/-雌性小鼠生成的胚胎数量明显减少.Rev-erb-α-/-雌性小鼠卵巢存在各级卵泡,并且结构与野生型(Rev-erb-α+/+)雌性小鼠相比无明显差异.Rev-erb-α-/-雌性小鼠的生理周期较Rev-erb-α+/+小鼠周期长约3.22 d,较Rev-erb-α+/+雌性小鼠延长63.5%.以上结果提示,生物钟基因Rev-erb-α缺失导致雌性小鼠生理周期明显延长,可能是影响雌性小鼠生育的原因之一.因此,生物节律的稳定对于生理周期具有重要作用.%The circadian clock has been linked to female reproductive physiology and endocrine in mammals.Epidemiological studies of female shift workers have shown increased rates of abnormal reproduction and adverse pregnancy.But little is known how the circadian rhythms affect reproduction.The aim of the present study was to investigate the influences of circadian rhythms on estrous cycle in female mice using clock gene Rev-erb-α knock out (Rev-erb-α-/-) mice.To test the fertility of Rev-erb-α-/-mice,litter sizes were counted after mating with C57BL/6J male mice.HE staining was used to observe the change of follicle development.The number of embryos of Rev-erb-α+/+ and Rev

  17. Stochastic Dynamics of the Multi-State Voter Model Over a Network Based on Interacting Cliques and Zealot Candidates

    Science.gov (United States)

    Palombi, Filippo; Toti, Simona

    2014-07-01

    The stochastic dynamics of the multi-state voter model is investigated on a class of complex networks made of non-overlapping cliques, each hosting a political candidate and interacting with the others via Erdős-Rényi links. Numerical simulations of the model are interpreted in terms of an ad-hoc mean field theory, specifically tuned to resolve the inter/intra-clique interactions. Under a proper definition of the thermodynamic limit (with the average degree of the agents kept fixed while increasing the network size), the model is found to display the empirical scaling discovered by Fortunato and Castellano (Phys Rev Lett 99(13):138701, 2007) , while the vote distribution resembles roughly that observed in Brazilian elections.

  18. Losers, Food, and Sex. Clerical Masculinity in the BBC Sitcom Rev.

    Directory of Open Access Journals (Sweden)

    Alexander Ornella

    2016-11-01

    Full Text Available Clerical masculinities, much like their lay/secular counterparts, often appear unchang¬ing because they are the products of naturalization processes. Clerical masculinities, however, are far from stable, for they live and breathe the dynamics of both their socio-religious context and their secular “others”. The BBC sitcom Rev. (BBC2, UK 2010–2014 is a refreshing take on the everyday life and problems of a vicar in the Church of England trying to avoid stereotypes that often come with clerical roles. Rev. (2010–2014 can be interpreted as an attempt to explore the negotiation processes of masculinity within an institution that is involved in the “production” of religion and gender roles. It shows that being a man in an institutional setting is as much a perfor¬mance as it is a more or less successful negotiation of other people’s expectations and one’s own worldview. In particular, the main male clerical characters in Rev. (2010– 2014 inhabit a position of power but all have their flaws. They can best be understood as losers whose clash with masculine systems renders them more human.

  19. Reply to ``Comment on `Dynamic properties in a family of competitive growing models' ''

    Science.gov (United States)

    Horowitz, Claudio M.; Albano, Ezequiel V.

    2010-03-01

    In an early paper [C. M. Horowitz and E. V. Albano, Phys. Rev. E 73, 031111 (2006)], we studied growing models, generically called X/RD , such that a particle is attached to the aggregate with probability p following the mechanisms of a generic model X and at random (random deposition) with probability (1-p) . We also formulated scaling relationships that are expected to hold in the limits p→0 and L→∞ , where L is the sample side. In the previous comment, Kolakowska and Novotny (KN) state that our scaling hypothesis does not hold. Here, we show that the criticisms of KN are outlined by analyzing data out of the proper scaling regime and consequently they are groundless and can be disregarded.

  20. Models for Small-Scale Structure on Cosmic Strings: II. Scaling and its stability

    CERN Document Server

    Vieira, J P P; Shellard, E P S

    2016-01-01

    We make use of the formalism described in a previous paper [Martins {\\it et al.} Phys. Rev. D90 (2014) 043518] to address general features of wiggly cosmic string evolution. In particular, we highlight the important role played by poorly understood energy loss mechanisms and propose a simple ansatz which tackles this problem in the context of an extended velocity-dependent one-scale model. We find a general procedure to determine all the scaling solutions admitted by a specific string model and study their stability, enabling a detailed comparison with future numerical simulations. A simpler comparison with previous Goto-Nambu simulations supports earlier evidence that scaling is easier to achieve in the matter era than in the radiation era. In addition, we also find that the requirement that a scaling regime be stable seems to notably constrain the allowed range of energy loss parameters.

  1. LRS Bianchi type-II string cosmological models in a modified theory of gravitation

    Science.gov (United States)

    Kanakavalli, T.; Ananda Rao, G.; Reddy, D. R. K.

    2017-03-01

    This paper is devoted to the investigation of spatially homogeneous anisotropic LRS Bianchi type-II cosmological models with string source in a modified theory of gravitation formulated by Harko et al. (Phys. Rev. D 84:024020, 2011) which is universally known as f( R, T) gravity. Here R is the Ricci scalar and T is the trace of the energy momentum tensor. By solving the field equation we have presented massive string and Takabyasi or p-string models in this theory. However it is interesting to note that geometric string in this space-time does not exist in this theory. Physical and geometrical properties of the strings obtained are also discussed.

  2. Effects of Mass Media and Cultural Drift in a Nonequilibrium Model for Social Influence

    CERN Document Server

    Mazzitello, K I; Dossetti, V; Candia, Juli\\'an; Mazzitello, Karina I.

    2006-01-01

    In the context of an extension of Axelrod's nonequilibrium model for social influence, we study the interplay and competition between the cultural drift, represented as random perturbations, and mass media, introduced by means of an external homogeneous field. Unlike previous studies [J. C. Gonz\\'alez-Avella {\\it et al}, Phys. Rev. E {\\bf 72}, 065102(R) (2005)], the mass media coupling proposed here is capable of affecting the cultural traits of any individual in the society, including those who do not share any features with the external message. A noise-driven transition is found: for large noise rates, both the ordered (culturally polarized) phase and the disordered (culturally fragmented) phase are observed, while, for lower noise rates, the ordered phase prevails. In the former case, the external field is found to induce cultural ordering, a behavior opposite to that reported in previous studies using a different prescription for the mass media interaction. We compare the predictions of this model to sta...

  3. An approximation formula for the Bloch-Siegert shift of the Rabi model

    CERN Document Server

    Rapedius, K

    2015-01-01

    So far the Bloch-Siegert shift of the Rabi model has only been calculated numerically or by means of perturbation theory valid in either the weak or strong driving regime only. Recently Yan, L\\"u, and Zheng [Phys.~Rev.~A {\\bf 91}, 053834 (2015)] showed how to reduce the problem to solving a system of three nonlinear equations. Here, we pursue an alternative approach based on a perturbation expansion extrapolation technique. We are thus able to derive an explicit analytical approximation formula for the Bloch-Siegert shift of the Rabi model which is valid for all parameter regimes from weak to strong driving. Comparison with numerically exact results reveals an excellent agreement over the entire driving-strength range.

  4. Renormalization of spin polarized itinerant electron bands in the normal state of a model ferromagnetic superconductor

    Institute of Scientific and Technical Information of China (English)

    Ma Lei; Huang Ai-Qun; Li Jun

    2011-01-01

    This paper studies the normal state properties of itinerant electrons in a toy model, which is constructed according to the model for coexisting ferromagnetism and superconductivity proposed by Suhl [Suhl H 2001 Phys. Rev. Lett. 87 167007]. In this theory with ferromagnetic ordering based on localized spins, the exchange interaction J between conduction electrons and localized spin is taken as the pairing glue for s-wave superconductivity. It shows that this J term will first renormalize the normal state single conduction electron structures substantially. It finds dramatically enhanced or suppressed magnetization of itinerant electrons for positive or negative J. Singlet Cooper pairing can be ruled out due to strong spin polarisation in the J > 0 case while a narrow window for s-wave superconductivity is opened around some ferromagnetic J.

  5. Model for twin electromagnons and magnetically induced oscillatory polarization in multiferroic RMnO3

    Science.gov (United States)

    de Sousa, Rogério; Stenberg, Markku

    2010-03-01

    We propose a model [1] for the pair of electromagnon excitations observed in the class of multiferroic materials RMnO3 (R is a rare-earth ion). The model is based on a harmonic cycloid ground state interacting with a zone-edge magnon and its twin excitation separated in momentum space by two times the cycloid wave vector. The pair of electromagnons is activated by cross coupling between magnetostriction and spin-orbit interactions. Remarkably, the spectral weight of the twin electromagnon is directly related to the presence of a magnetically induced oscillatory polarization in the ground state. This leads to the surprising prediction that TbMnO3 has an oscillatory polarization with amplitude 50 times larger than its uniform polarization. [4pt] [1] M.P.V. Stenberg and R. de Sousa, Phys. Rev. B 80, 094419 (2009) (Editors' suggestion).

  6. Characterization of the HIV-1 RNA associated proteome identifies Matrin 3 as a nuclear cofactor of Rev function

    Directory of Open Access Journals (Sweden)

    Myers Michael P

    2011-07-01

    Full Text Available Abstract Background Central to the fully competent replication cycle of the human immunodeficiency virus type 1 (HIV-1 is the nuclear export of unspliced and partially spliced RNAs mediated by the Rev posttranscriptional activator and the Rev response element (RRE. Results Here, we introduce a novel method to explore the proteome associated with the nuclear HIV-1 RNAs. At the core of the method is the generation of cell lines harboring an integrated provirus carrying RNA binding sites for the MS2 bacteriophage protein. Flag-tagged MS2 is then used for affinity purification of the viral RNA. By this approach we found that the viral RNA is associated with the host nuclear matrix component MATR3 (Matrin 3 and that its modulation affected Rev activity. Knockdown of MATR3 suppressed Rev/RRE function in the export of unspliced HIV-1 RNAs. However, MATR3 was able to associate with Rev only through the presence of RRE-containing viral RNA. Conclusions In this work, we exploited a novel proteomic method to identify MATR3 as a cellular cofactor of Rev activity. MATR3 binds viral RNA and is required for the Rev/RRE mediated nuclear export of unspliced HIV-1 RNAs.

  7. Status report of seabird surveys at Horns Rev, 2000-2001

    Energy Technology Data Exchange (ETDEWEB)

    Kjaer Christensen, T.; Clausager, I.; Krag Petersen, I. [NERI, Dept. of Coastal Zone Ecology, Roskilde (Denmark)

    2002-07-01

    The present report presents the results of three bird surveys conducted in the Horns Rev area during the second half of 2001. Due to poor weather conditions in December 2001, the last survey was, however, performed on 7 January 2002. The surveys are part of the base-line investigations of birds performed in relation to the proposed construction of an offshore wind farm at Horns Rev in the Danish part of the North Sea ca 14 km southwest of Blaevandshuk. The results of the surveys during August 2001 - January 2002 are presented together with the results obtained during the period August 2000 - April 2001, and are also compared to results obtained during the period August 1999 - April 2000. Based on the distribution of the most abundant bird species recorded during 16 aerial surveys performed during August 1999 - January 2002, there were no indications that the wind farm area was of any particular importance to the birds' exploitation of the Horns Rev area. Fish-eating species like divers, gannet, terns, auks and gulls generally showed scattered and variable distributions, mainly occurring in the areas north and south of Horns Rev, and with low numbers on the reef proper and within the planned wind farm area. The distribution of benthic foraging species, eider and common Scoter, showed that they mainly exploited the coastal parts of the area off Blaevandshuk and Skallingen, although common scoter was found in relatively high numbers on the southeast slopes of the Horns Rev and within the wind farm area in the April 2001 survey. Common scoters occurred in very high numbers in January 2002. This was probably related to increased immigration of birds from the inner Danish waters during a cold period in late December 2001. Preference analyses of bird exploitation of the Horns Rev area showed that if the birds completely avoid the wind farm area after erection of the wind turbines, this will affect less than 1% of the various species, except divers where 1.58% will be

  8. Large eddy simulation of transitional flow in an idealized stenotic blood vessel: evaluation of subgrid scale models.

    Science.gov (United States)

    Pal, Abhro; Anupindi, Kameswararao; Delorme, Yann; Ghaisas, Niranjan; Shetty, Dinesh A; Frankel, Steven H

    2014-07-01

    In the present study, we performed large eddy simulation (LES) of axisymmetric, and 75% stenosed, eccentric arterial models with steady inflow conditions at a Reynolds number of 1000. The results obtained are compared with the direct numerical simulation (DNS) data (Varghese et al., 2007, "Direct Numerical Simulation of Stenotic Flows. Part 1. Steady Flow," J. Fluid Mech., 582, pp. 253-280). An inhouse code (WenoHemo) employing high-order numerical methods for spatial and temporal terms, along with a 2nd order accurate ghost point immersed boundary method (IBM) (Mark, and Vanwachem, 2008, "Derivation and Validation of a Novel Implicit Second-Order Accurate Immersed Boundary Method," J. Comput. Phys., 227(13), pp. 6660-6680) for enforcing boundary conditions on curved geometries is used for simulations. Three subgrid scale (SGS) models, namely, the classical Smagorinsky model (Smagorinsky, 1963, "General Circulation Experiments With the Primitive Equations," Mon. Weather Rev., 91(10), pp. 99-164), recently developed Vreman model (Vreman, 2004, "An Eddy-Viscosity Subgrid-Scale Model for Turbulent Shear Flow: Algebraic Theory and Applications," Phys. Fluids, 16(10), pp. 3670-3681), and the Sigma model (Nicoud et al., 2011, "Using Singular Values to Build a Subgrid-Scale Model for Large Eddy Simulations," Phys. Fluids, 23(8), 085106) are evaluated in the present study. Evaluation of SGS models suggests that the classical constant coefficient Smagorinsky model gives best agreement with the DNS data, whereas the Vreman and Sigma models predict an early transition to turbulence in the poststenotic region. Supplementary simulations are performed using Open source field operation and manipulation (OpenFOAM) ("OpenFOAM," http://www.openfoam.org/) solver and the results are inline with those obtained with WenoHemo.

  9. Grain coarsening in two-dimensional phase-field models with an orientation field

    Science.gov (United States)

    Korbuly, Bálint; Pusztai, Tamás; Henry, Hervé; Plapp, Mathis; Apel, Markus; Gránásy, László

    2017-05-01

    In the literature, contradictory results have been published regarding the form of the limiting (long-time) grain size distribution (LGSD) that characterizes the late stage grain coarsening in two-dimensional and quasi-two-dimensional polycrystalline systems. While experiments and the phase-field crystal (PFC) model (a simple dynamical density functional theory) indicate a log-normal distribution, other works including theoretical studies based on conventional phase-field simulations that rely on coarse grained fields, like the multi-phase-field (MPF) and orientation field (OF) models, yield significantly different distributions. In a recent work, we have shown that the coarse grained phase-field models (whether MPF or OF) yield very similar limiting size distributions that seem to differ from the theoretical predictions. Herein, we revisit this problem, and demonstrate in the case of OF models [R. Kobayashi, J. A. Warren, and W. C. Carter, Physica D 140, 141 (2000), 10.1016/S0167-2789(00)00023-3; H. Henry, J. Mellenthin, and M. Plapp, Phys. Rev. B 86, 054117 (2012), 10.1103/PhysRevB.86.054117] that an insufficient resolution of the small angle grain boundaries leads to a log-normal distribution close to those seen in the experiments and the molecular scale PFC simulations. Our paper indicates, furthermore, that the LGSD is critically sensitive to the details of the evaluation process, and raises the possibility that the differences among the LGSD results from different sources may originate from differences in the detection of small angle grain boundaries.

  10. Quantifying interactions between real oscillators with information theory and phase models: Application to cardiorespiratory coupling

    Science.gov (United States)

    Zhu, Yenan; Hsieh, Yee-Hsee; Dhingra, Rishi R.; Dick, Thomas E.; Jacono, Frank J.; Galán, Roberto F.

    2013-01-01

    Interactions between oscillators can be investigated with standard tools of time series analysis. However, these methods are insensitive to the directionality of the coupling, i.e., the asymmetry of the interactions. An elegant alternative was proposed by Rosenblum and collaborators [M. G. Rosenblum, L. Cimponeriu, A. Bezerianos, A. Patzak, and R. Mrowka, Phys. Rev. E 65, 041909 (2002); M. G. Rosenblum and A. S. Pikovsky, Phys. Rev. E 64, 045202 (2001)] which consists in fitting the empirical phases to a generic model of two weakly coupled phase oscillators. This allows one to obtain the interaction functions defining the coupling and its directionality. A limitation of this approach is that a solution always exists in the least-squares sense, even in the absence of coupling. To preclude spurious results, we propose a three-step protocol: (1) Determine if a statistical dependency exists in the data by evaluating the mutual information of the phases; (2) if so, compute the interaction functions of the oscillators; and (3) validate the empirical oscillator model by comparing the joint probability of the phases obtained from simulating the model with that of the empirical phases. We apply this protocol to a model of two coupled Stuart-Landau oscillators and show that it reliably detects genuine coupling. We also apply this protocol to investigate cardiorespiratory coupling in anesthetized rats. We observe reciprocal coupling between respiration and heartbeat and that the influence of respiration on the heartbeat is generally much stronger than vice versa. In addition, we find that the vagus nerve mediates coupling in both directions. PMID:23496550

  11. Phenomenological Model of Charge Localization in the Layered Manganites

    Science.gov (United States)

    Gray, Kenneth E.; Badica, Elvira

    2003-03-01

    The connection of magnetic order with charge delocalization in manganites has received considerable interest recently, and the need to go beyond double exchange (DE) to explain the localized state above TC was first introduced by Millis, et al [Phys. Rev. Lett. 74, 5144 (1995)]. In this spirit, we propose a simple model that can explain the various ground states for layered manganites, La_2-2xSr_1+2xMn_2O_7, in terms of the relative energy gain due to DE compared to a phenomenological localization parameter. This model includes antiferromagnetic (AF) superexchange and thus can also be used for layered manganites exhibiting A-type AF order within the bilayer that we find to be either conducting (x=0.54) or insulating (x=0.48). In a magnetic field, the latter case shows a first order metal-insulator transition that is a signature of a crossover of these energies of the localized and delocalized states. Experimentally, localized states seem to be most strongly favored for x 0.50 although the low-temperature state is not always the CE state and quasi-bi-strip charge order has been observed for x=0.48 by Kubota, et al [J. Phys. Soc. Japan, 69, 1986 (2000)].

  12. Continuous time limits of the utterance selection model

    Science.gov (United States)

    Michaud, Jérôme

    2017-02-01

    In this paper we derive alternative continuous time limits of the utterance selection model (USM) for language change [G. J. Baxter et al., Phys. Rev. E 73, 046118 (2006), 10.1103/PhysRevE.73.046118]. This is motivated by the fact that the Fokker-Planck continuous time limit derived in the original version of the USM is only valid for a small range of parameters. We investigate the consequences of relaxing these constraints on parameters. Using the normal approximation of the multinomial approximation, we derive a continuous time limit of the USM in the form of a weak-noise stochastic differential equation. We argue that this weak noise, not captured by the Kramers-Moyal expansion, cannot be neglected. We then propose a coarse-graining procedure, which takes the form of a stochastic version of the heterogeneous mean field approximation. This approximation groups the behavior of nodes of the same degree, reducing the complexity of the problem. With the help of this approximation, we study in detail two simple families of networks: the regular networks and the star-shaped networks. The analysis reveals and quantifies a finite-size effect of the dynamics. If we increase the size of the network by keeping all the other parameters constant, we transition from a state where conventions emerge to a state where no convention emerges. Furthermore, we show that the degree of a node acts as a time scale. For heterogeneous networks such as star-shaped networks, the time scale difference can become very large, leading to a noisier behavior of highly connected nodes.

  13. Leidenfrost effect: Accurate drop shape modeling and refined scaling laws.

    Science.gov (United States)

    Sobac, B; Rednikov, A; Dorbolo, S; Colinet, P

    2014-11-01

    We here present a simple fitting-parameter-free theory of the Leidenfrost effect (droplet levitation above a superheated plate) covering the full range of stable shapes, i.e., from small quasispherical droplets to larger puddles floating on a pocketlike vapor film. The geometry of this film is found to be in excellent quantitative agreement with the interferometric measurements of Burton et al. [Phys. Rev. Lett. 109, 074301 (2012)PRLTAO0031-900710.1103/PhysRevLett.109.074301]. We also obtain new scalings generalizing classical ones derived by Biance et al. [Phys. Fluids 15, 1632 (2003)PHFLE61070-663110.1063/1.1572161] as far as the effect of plate superheat is concerned and highlight the relative role of evaporation, gravity, and capillarity in the vapor film. To further substantiate these findings, a treatment of the problem by matched asymptotic expansions is also presented.

  14. Studying the entropy excess and entropy excess ratio in (105,106,107)Pd within BCS model

    CERN Document Server

    Rahmatinejad, Azam; Razavi, Rohallah

    2015-01-01

    Pairing correlations and their influence on nuclear properties has been studied within BCS model. Using this theoretical model with inclusion of pairing interaction between nucleons, nuclear level density and entropy of Pd(105,106,107) have been extracted. The results well coincide with the empirical values of the nuclear level densities obtained by Oslo group. Then the entropy excess of Pd107 and Pd105 compared to Pd106 as a function of the temperature has been studied. Also the role of neutron and proton system in entropy excess have been investigated by the using of the entropy excess ratio proposed by Razavi et al. [R. Razavi, A.N. Behkami, S. Mohammadi, and M. Gholami, Phys. Rev. C 86, 047303 (2012)].

  15. Theoretical description of adiabatic laser alignment and mixed-field orientation: the need for a non-adiabatic model

    CERN Document Server

    Omiste, J J; Schmelcher, P; González-Férez, R; Holmegaard, L; Nielsen, J H; Stapelfeldt, H; Küpper, J

    2011-01-01

    We present a theoretical study of recent laser-alignment and mixed-field-orientation experiments of asymmetric top molecules. In these experiments, pendular states were created using linearly polarized strong ac electric fields from pulsed lasers in combination with weak electrostatic fields. We compare the outcome of our calculations with experimental results obtained for the prototypical large molecule benzonitrile (C$_7$H$_5$N) [J.L. Hansen et al, Phys. Rev. A, 83, 023406 (2011)] and explore the directional properties of the molecular ensemble for several field configurations, i.e., for various field strengths and angles between ac and dc fields. For perpendicular fields one obtains pure alignment, which is well reproduced by the simulations. For tilted fields, we show that a fully adiabatic description of the process does not reproduce the experimentally observed orientation, and it is mandatory to use a diabatic model for population transfer between rotational states. We develop such a model and compare ...

  16. Plane Symmetric Dark Energy Models in the Form of Wet Dark Fluid in ${f(R, T )}$ Gravity

    Indian Academy of Sciences (India)

    V. R. Chirde; S. H. Shekh

    2016-06-01

    In this paper, we have investigated the plane symmetric space-time with wet dark fluid (WDF), which is a candidate for dark energy, in the framework of $f(R, T)$ gravity Harko et al. 2011, Phys. Rev. D, 84, 024020), where $R$ and $T$ denote the Ricci scalar and the trace of the energy–momentum tensor respectively. We have used the equation of state in the form of WDF for the dark energy component of the Universe. It is modeled on the equation of state $p = \\omega(\\rho−\\rho^∗)$. The exact solutions to the corresponding field equations are obtained for power-law and exponential volumetric expansion. The geometrical and physical parameters for both the models are studied. Also, we have discussed the well-known astrophysical phenomena, namely the look-back time, proper distance, the luminosity distance and angular diameter distance with red shift.

  17. A control method for congested traffic induced by bottlenecks in the coupled map car-following model

    Science.gov (United States)

    Zhao, Xiaomei; Gao, Ziyou

    2006-07-01

    We present a simple control method to suppress the traffic congestion in the coupled map car-following model under open boundary, based on the pioneer work of Konishi et al. [Coupled map car-following model and its delayed-feedback control, Phys. Rev. E 60 (1999) 4000-4007]. Theoretically, it is proven that the congested traffic in the traffic system could be suppressed by using the method. Comparison between our method and the method of Konishi et al. is carried out. The simulation results show the temporal behavior obtained by our method is better than that by the method of Konishi et al., although both the methods can suppress the traffic jam. The simulation results demonstrate that the traffic system can move into a homogeneous phase and the flux has great increases by the introduction of the control signal. The simulation results are in good agreement with the theoretical analysis.

  18. Highly magnetized white dwarf as a possible alternate to neutron star to resolve shortcoming of magnetar model

    Science.gov (United States)

    Mukhopadhyay, Banibrata; Rao, A. R.; Das, Upasana; Subramanian, Sathyawageeswar; Bhattacharya, Mukul

    2016-07-01

    Since 2012, in a series of paper (so far 15, published in Phys. Rev. Lett., 110, 071102, 2013; ApJLett., 767, 14, 2013; MNRAS, 454, 752, 2015, etc.), we have been exploring the possible existence of highly magnetized super-Chandrasekhar white dwarfs. Not only their mass is highly super-Chandrasekhar, they could be much smaller in size compared to the conventional white dwarfs. Here, first I plan to give an overview of the scientific evolution of the model and its current status. Subsequently, on establishing its reliability, I will show that it could be a potential candidate to explain the features lying with soft gamma-ray repeaters and anomalous X-ray pulsars, some of which the conventional neutron state based model, based on huge observationally unconfirmed yet surface magnetic fields, cannot explain. I will also highlight that our highly magnetized white dwarfs should exhibit very low luminosity, hence are difficult to observe directly.

  19. Universe of quantum whirls in the final theory spiral field model. Basic ideas for a compatible physics and a consistent nature science. 2. rev. ed.; Universum der Quantenwirbel in der Finaltheorie Spiralfeldmodell. Grundgedanken fuer eine kompatible Physik und eine konsistente Naturwissenschaft

    Energy Technology Data Exchange (ETDEWEB)

    Hartje, Udo A.J.

    2007-07-01

    changing the radiation itself into 'electrons' which rotate on paths. The Classical Physics and the Quantum Physics merge with a new radiation and particle model in the ''Spiral Field Model'' to an united primary edifice of ideas. Atoms and other particles must be analyzed on a new basis in which the rich fund of recognized knowledge will help. Some puzzles come to solution alone by the new position. Other unsolved problems of the nature science must be brought in connection with the strange thoughts; that the individual aspects will visibly. A single person is not able to it in the face of the gigantic mountain at accumulated knowledge. (orig.)

  20. Universe of quantum whirls in the final theory spiral field model. Basic ideas for a compatible physics and a consistent nature science. 3. rev. ed.; Universum der Quantenwirbel in der Finaltheorie Spiralfeldmodell. Grundgedanken fuer eine kompatible Physik und eine konsistente Naturwissenschaft

    Energy Technology Data Exchange (ETDEWEB)

    Hartje, Udo A.J.

    2008-07-01

    changing the radiation itself into 'electrons' which rotate on paths. The Classical Physics and the Quantum Physics merge with a new radiation and particle model in the ''Spiral Field Model'' to an united primary edifice of ideas. Atoms and other particles must be analyzed on a new basis in which the rich fund of recognized knowledge will help. Some puzzles come to solution alone by the new position. Other unsolved problems of the nature science must be brought in connection with the strange thoughts; that the individual aspects will visibly. A single person is not able to it in the face of the gigantic mountain at accumulated knowledge. (orig.)

  1. The phase transition in the anisotropic Heisenberg model with long range dipolar interactions

    Energy Technology Data Exchange (ETDEWEB)

    Mól, L.A.S., E-mail: lucasmol@fisica.ufmg.br; Costa, B.V., E-mail: bvc@fisica.ufmg.br

    2014-03-15

    In this work we have used extensive Monte Carlo calculations to study the planar to paramagnetic phase transition in the two-dimensional anisotropic Heisenberg model with dipolar interactions (AHd) considering the true long-range character of the dipolar interactions by means of the Ewald summation. Our results are consistent with an order–disorder phase transition with unusual critical exponents in agreement with our previous results for the Planar Rotator model with dipolar interactions. Nevertheless, our results disagree with the Renormalization Group results of Maier and Schwabl [Phys. Rev. B, 70, 134430 (2004)] [13] and the results of Rapini et al. [Phys. Rev. B, 75, 014425 (2007)] [12], where the AHd was studied using a cut-off in the evaluation of the dipolar interactions. We argue that besides the long-range character of dipolar interactions their anisotropic character may have a deeper effect in the system than previously believed. Besides, our results show that the use of a cut-off radius in the evaluation of dipolar interactions must be avoided when analyzing the critical behavior of magnetic systems, since it may lead to erroneous results. - Highlights: • The anisotropic Heisenberg model with dipolar interactions is studied. • True long-range interactions were considered by means of Ewald summation. • We found an order–disorder phase transition with unusual critical exponents. • Previous results show a different behavior when a cut-off radius is introduced. • The use of a cut-off radius must be avoided when dealing with dipolar systems.

  2. Applications of the predictability of the Coherent Noise Model to aftershock sequences

    Science.gov (United States)

    Christopoulos, Stavros-Richard; Sarlis, Nicholas

    2014-05-01

    A study [1] of the coherent noise model [2-4] in natural time [5-7] has shown that it exhibits predictability. Interestingly, one of the predictors suggested [1] for the coherent noise model can be generalized and applied to the case of (real) aftershock sequences. The results obtained [8] so far are beyond chance. Here, we apply this approach to several aftershock sequences of strong earthquakes with magnitudes Mw ≥6.9 in Indonesia, California and Greece, including the Mw9.2 earthquake that occurred on 26 December 2004 in Sumatra. References. [1] N. V. Sarlis and S.-R. G. Christopoulos, Predictability of the coherent-noise model and its applications, Physical Review E, 85, 051136, 2012. [2] M.E.J. Newman, Self-organized criticality, evolution and the fossil extinction record, Proc. R. Soc. London B, 263, 1605-1610, 1996. [3] M. E. J. Newman and K. Sneppen, Avalanches, scaling, and coherent noise, Phys. Rev. E, 54, 6226-6231, 1996. [4] K. Sneppen and M. Newman, Coherent noise, scale invariance and intermittency in large systems, Physica D, 110, 209 - 222. [5] P. Varotsos, N. Sarlis, and E. Skordas, Spatiotemporal complexity aspects on the interrelation between Seismic Electric Signals and seismicity, Practica of Athens Academy, 76, 294-321, 2001. [6] P.A. Varotsos, N.V. Sarlis, and E.S. Skordas, Long-range correlations in the electric signals that precede rupture, Phys. Rev. E, 66, 011902, 2002. [7] Varotsos P. A., Sarlis N. V. and Skordas E. S., Natural Time Analysis: The new view of time. Precursory Seismic Electric Signals, Earthquakes and other Complex Time-Series (Springer-Verlag, Berlin Heidelberg) 2011. [8] N. V. Sarlis and S.-R. G. Christopoulos, "Visualization of the significance of Receiver Operating Characteristics based on confidence ellipses", Computer Physics Communications, http://dx.doi.org/10.1016/j.cpc.2013.12.009

  3. Agent-based models for latent liquidity and concave price impact

    Science.gov (United States)

    Mastromatteo, Iacopo; Tóth, Bence; Bouchaud, Jean-Philippe

    2014-04-01

    We revisit the "ɛ-intelligence" model of Tóth et al. [Phys. Rev. X 1, 021006 (2011), 10.1103/PhysRevX.1.021006], which was proposed as a minimal framework to understand the square-root dependence of the impact of meta-orders on volume in financial markets. The basic idea is that most of the daily liquidity is "latent" and furthermore vanishes linearly around the current price, as a consequence of the diffusion of the price itself. However, the numerical implementation of Tóth et al. (2011) was criticized as being unrealistic, in particular because all the "intelligence" was conferred to market orders, while limit orders were passive and random. In this work, we study various alternative specifications of the model, for example, allowing limit orders to react to the order flow or changing the execution protocols. By and large, our study lends strong support to the idea that the square-root impact law is a very generic and robust property that requires very few ingredients to be valid. We also show that the transition from superdiffusion to subdiffusion reported in Tóth et al. (2011) is in fact a crossover but that the original model can be slightly altered in order to give rise to a genuine phase transition, which is of interest on its own. We finally propose a general theoretical framework to understand how a nonlinear impact may appear even in the limit where the bias in the order flow is vanishingly small.

  4. WBN-1 Cycle 10 TPBAR Tritium Release, Deduced From Analysis of RCS Data TTP-1-3046-00, Rev 0

    Energy Technology Data Exchange (ETDEWEB)

    Shaver, Mark W.; Niehus, Mark T.; Love, Edward F.

    2012-02-19

    This document contains the calculation of the TPBAR tritium release from the Mark 9.2 design TPBARs irradiated in WBN cycle 10. The calculation utilizes the generalized cycle analysis methodology given in TTP-1-3045 Rev. 0.

  5. DC Brushless Motor Control Design and Preliminary Testing for Independent 4-Wheel Drive Rev-11 Robotic Platform

    Directory of Open Access Journals (Sweden)

    Roni Permana Saputra

    2012-03-01

    Full Text Available This paper discusses the design of control system for brushless DC motor using microcontroller ATMega 16 that will be applied to an independent 4-wheel drive Mobile Robot LIPI version 2 (REV-11. The control system consists of two parts which are brushless DC motor control module and supervisory control module that coordinates the desired command to the motor control module. To control the REV-11 platform, supervisory control transmit the reference data of speed and direction of motor to control the speed and direction of each actuator on the platform REV-11. From the test results it is concluded that the designed control system work properly to coordinate and control the speed and direction of motion of the actuator motor REV-11 platform. 

  6. Horns Rev offshore wind farm. Environmental impact assessment of sea bottom and marine biology

    Energy Technology Data Exchange (ETDEWEB)

    Leonhard, S.B.

    2000-03-15

    An Environmental Impact Assessment (EIA) of a planned 150 MW offshore wind farm at Horns Rev has been carried out for the marine biology and sea bottom in the area, and includes vegetation and benthic fauna. The study forms part of a total EIA of the planned offshore wind farm. This EIA study has been drawn up in accordance with the guidelines laid down by the Ministry of Environment and Energy in the publication, 'Guidelines for preparation of EIAstudies for offshore wind farms. Horns Rev is situated off Blaevands Huk, which is Denmark's most westerly point. It is a shallow reef with water depths between 2 and 9 metres and is primarily composed of sand, gravel and pebbles. The area designated for the wind farm lies directly south of Horns Rev and is dominated by sand with a median particle size of 0.3 mm. Along the edges, towards areas of greater depth, the particle size increases. There are areas of fine sand in the deepest area, and in isolated pockets within the proposed wind farm site. The sediment is characterised by a very low (<1%) organic matter content. On the basis of the expected impact from the establishment of the wind farm, it is not deemed necessary to carry out special programmes during the construction phase for monitoring of the environmental-biological conditions. A monitoring and control programme is recommended during the production phase in order to follow the copper concentration in bivalves, or alternatively to initiate recovery or elimination of the copper-laden waste. A control programme is recommended during the production phase in order to follow the establishment and succession of the fouling community on the wind turbine foundations and scour-protecting revetments. (BA)

  7. The effect of subgrid-scale models on grid-scale/subgrid-scale energy transfers in large-eddy simulation of incompressible magnetohydrodynamic turbulence

    Science.gov (United States)

    Kessar, M.; Balarac, G.; Plunian, F.

    2016-10-01

    In this work, the accuracy of various models used in large-eddy simulations (LES) of incompressible magnetohydrodynamic (MHD) turbulence is evaluated. Particular attention is devoted to the capabilities of models to reproduce the transfers between resolved grid- and subgrid-scales. The exact global balance of MHD turbulent flows is first evaluated from direct numerical simulation (DNS) database. This balance is controlled by the transfers between scales and between kinetic and magnetic energies. Two cases of forced homogeneous isotropic MHD turbulent flows are considered, with and without injecting large scale helicity. The strong helical case leads to domination of the magnetic energy due to an inverse cascade [A. Brandenburg, Astrophys. J. 550(2), 824 (2001); N. E. Haugen et al., Phys. Rev. E 70(1), 016308 (2004)]. The energy transfers predicted by various models are then compared with the transfer extracted from DNS results. This allows to discriminate models classically used for LES of MHD turbulence. In the non-helical case, the Smagorinsky-like model [M. L. Theobald et al., Phys. Plasmas 1, 3016 (1994)] and a mixed model are able to perform stable LES, but the helical case is a more demanding test and all the models lead to unstable simulations.

  8. Pilot power based rate control in CDMA 2000 1x EV-DO Rev-A

    Institute of Scientific and Technical Information of China (English)

    LIU Xiao-feng; GU Jian; YANG Hong-wen

    2008-01-01

    This article proposes a new algorithm to improvethe rate control efficiency of enhanced reverse link mediumaccess control (RLMAC) in the code division multiple access(CDMA) lx EV-DO release A(Rev. A) system. The newalgorithm brings reverse access terminal (AT) pilot power tothe RLMAC rate control procedure and makes it easier for alow pilot power user to increase its data rate when the systemis slightly loaded and harder to decrease its date rate when thesystem is heavily loaded. Numerical results of system levelsimulations show that the new algorithm can bring highersystem throughput, lower AT transmission power, and lowersystem load.

  9. De novo mutations in Plxnd1 and Rev3l cause mobius syndrome

    OpenAIRE

    Kayserili Karabey, Hülya; Tomas-Roca, Laura; Tsaalbi-Shtylik, Anastasia; Jansen, Jacob G.; Singh, Manvendra K.; Epstein, Jonathan A.; Altunoglu, Umut; Verzijl, Harriette; Soria, Laura; van Beusekom, Ellen; Roscioli, Tony; Iqbal, Zafar; Gilissen, Christian; Hoischen, Alexander; de Brouwer,Arjan P. M.; Erasmus, Corrie; Schubert, Dirk; Brunner, Han; Aytes, Antonio Perez; Marin, Faustino; Aroca, Pilar; Carta, Arturo; de Wind, Niels; Padberg, George W.; van Bokhoven, Hans

    2015-01-01

    ARTICLE Received 15 Nov 2014 | Accepted 17 Apr 2015 | Published 12 Jun 2015 De novo mutations in PLXND1 and REV3L cause Mo¨bius syndrome Laura Tomas-Roca1,2, Anastasia Tsaalbi-Shtylik3, Jacob G. Jansen3, Manvendra K. Singh4,5, Jonathan A. Epstein4, Umut Altunoglu6, Harriette Verzijl7, Laura Soria1, Ellen van Beusekom1, Tony Roscioli1,8, Zafar Iqbal1, Christian Gilissen1, Alexander Hoischen9, Arjan P.M. de Brouwer1, Corrie Erasmus7, Dirk Schubert10, Han Brunner1,11, Antoni...

  10. Bird numbers and distributions in the Horns Rev offshore wind farm area. Annual status report 2004

    Energy Technology Data Exchange (ETDEWEB)

    Krag Petersen, I.

    2005-07-01

    This report presents data from four aerial surveys of birds in the Horns Rev wind farm area in 2004. Three surveys from the winter and spring of 2004 are thoroughly reported here. The fourth survey of 9 September 2004 is reported in general terms, but not included in presentations of distribution and effect analyses of the wind farm. Data from this survey will be thoroughly dealt with in a future report. Including the four surveys of 2004, a total of 29 surveys have been performed in that area since August 1999. (au)

  11. Free Energy of the Uniform Electron Gas: Testing Analytical Models against First Principle Results

    CERN Document Server

    Groth, Simon; Bonitz, Michael

    2016-01-01

    The uniform electron gas is a key model system in the description of matter, including dense plasmas and solid state systems. However, the simultaneous occurence of quantum, correlation, and thermal effects makes the theoretical description challenging. For these reasons, over the last half century many analytical approaches have been developed the accuracy of which has remained unclear. We have recently obtained the first \\textit{ab initio} data for the exchange correlation free energy of the uniform electron gas [T. Dornheim \\textit{et al.}, Phys.~Rev.~Lett.~\\textbf{117}, 156403 (2016)] which now provides the opportunity to assess the quality of the mentioned approaches and parametrizations. Particular emphasis is put on the warm dense matter regime, where we find significant discrepancies between the different approaches.

  12. Motif based hierarchical random graphs: structural properties and critical points of an Ising model

    CERN Document Server

    Kotorowicz, M; 10.5488/CMP.14.13801

    2011-01-01

    A class of random graphs is introduced and studied. The graphs are constructed in an algorithmic way from five motifs which were found in [Milo R., Shen-Orr S., Itzkovitz S., Kashtan N., Chklovskii D., Alon U., Science, 2002, 298, 824-827]. The construction scheme resembles that used in [Hinczewski M., A. Nihat Berker, Phys. Rev. E, 2006, 73, 066126], according to which the short-range bonds are non-random, whereas the long-range bonds appear independently with the same probability. A number of structural properties of the graphs have been described, among which there are degree distributions, clustering, amenability, small-world property. For one of the motifs, the critical point of the Ising model defined on the corresponding graph has been studied.

  13. Comment on "More on Heisenberg's model for high energy nucleon-nucleon scattering"

    CERN Document Server

    Block, Martin M; Ha, Phuoc; Halzen, Francis

    2016-01-01

    We comment on the treatment of asymptotic black-disk scattering in a recent paper of Nastase and Sonnenschein, Phys.\\ Rev.\\ D\\ {\\bf 92}, 015028 (2015), on scattering in an updated version of the Heisenberg model which gives $pp$ and $\\bar{p}p$ cross sections which increase at very high energies as $\\ln^2s$. We show that the total cross section they define does not correspond to that measured in experiments, with the result that their limit for the ratio $\\sigma_{\\rm elas}/\\sigma_{\\rm tot}$ is too small by a factor 2. The correct ratio for black-disk scattering, $\\sigma_{\\rm elas}/\\sigma_{\\rm tot} \\rightarrow 1/2$ for $s\\rightarrow\\infty$, is strongly supported by experiment.

  14. Feedback control scheme of traffic jams based on the coupled map car-following model

    Science.gov (United States)

    Zhou, Tong; Sun, Di-Hua; Zhao, Min; Li, Hua-Min

    2013-09-01

    Based on the pioneering work of Konishi et al. [Phys. Rev. E (1999) 60 4000], a new feedback control scheme is presented to suppress traffic jams based on the coupled map car-following model under the open boundary condition. The effect of the safe headway on the traffic system is considered. According to the control theory, the condition under which traffic jams can be suppressed is analyzed. The results are compared with the previous results concerning congestion control. The simulations show that the suppression performance of our scheme on traffic jams is better than those of the previous schemes, although all the schemes can suppress traffic jams. The simulation results are consistent with theoretical analyses.

  15. GENERAL: A control method for congested traffic in the coupled map car-following model

    Science.gov (United States)

    Shen, Fei-Ying; Ge, Hong-Xia; Zhang, Hui; Yu, Han-Mei; Lei, Li

    2009-10-01

    Based on the pioneer work of Konishi et al, a new control method is presented to suppress the traffic congestion in the coupled map (CM) car-following model under an open boundary. A control signal concluding the velocity differences of the two vehicles in front is put forward. The condition under which the traffic jam can be contained is analyzed. The results are compared with that presented by Konishi et al [Phys. Rev. 1999 E 60 4000-4007]. The simulation results show that the temporal behavior obtained by our method is better than that by the Konishi's et al. method, although both the methods could suppress the traffic jam. The simulation results are consistent with the theoretical analysis.

  16. Geometrical mutual information at the tricritical point of the two-dimensional Blume-Capel model

    CERN Document Server

    Mandal, Ipsita; Melko, Roger G

    2016-01-01

    The spin-1 classical Blume-Capel model on a square lattice is known to exhibit a finite-temperature phase transition described by the tricritical Ising CFT in 1+1 space-time dimensions. This phase transition can be accessed with classical Monte Carlo simulations, which, via a replica-trick calculation, can be used to study the shape-dependence of the classical R\\'enyi entropies for a torus divided into two cylinders. From the second R\\'enyi entropy, we calculate the Geometrical Mutual Information (GMI) introduced by St\\'ephan et. al. [Phys. Rev. Lett. 112, 127204 (2014)] and use it to extract a numerical estimate for the value of the central charge near the tricritical point. By comparing to the known CFT result, $c=7/10$, we demonstrate how this type of GMI calculation can be used to estimate the position of the tricritical point in the phase diagram.

  17. A control method for congested traffic in the coupled map car-following model

    Institute of Scientific and Technical Information of China (English)

    Shen Fei-Ying; Ge Hong-Xia; Zhang Hui; Yu Han-Mei; Lei Li

    2009-01-01

    Based on the pioneer work of Konishi et al, a new control method is presented to suppress the traffic congestion in the coupled map (CM) car-following model under an open boundary. A control signal concluding the velocity differences of the two vehicles in front is put forward. The condition under which the traffic jam can be contained is analyzed. The results are compared with that presented by Konishi et al [Phys. Rev. 1999 E 60 4000-4007]. The simulation results show that the temporal behavior obtained by our method is better than that by the Konishi's et al. method, although both the methods could suppress the traffic jam. The simulation results are consistent with the theoretical analysis.

  18. Comparison of dynamical cores for NWP models: comparison of COSMO and Dune

    Science.gov (United States)

    Brdar, Slavko; Baldauf, Michael; Dedner, Andreas; Klöfkorn, Robert

    2013-06-01

    We present a range of numerical tests comparing the dynamical cores of the operationally used numerical weather prediction (NWP) model COSMO and the university code Dune, focusing on their efficiency and accuracy for solving benchmark test cases for NWP. The dynamical core of COSMO is based on a finite difference method whereas the Dune core is based on a Discontinuous Galerkin method. Both dynamical cores are briefly introduced stating possible advantages and pitfalls of the different approaches. Their efficiency and effectiveness is investigated, based on three numerical test cases, which require solving the compressible viscous and non-viscous Euler equations. The test cases include the density current (Straka et al. in Int J Numer Methods Fluids 17:1-22, 1993), the inertia gravity (Skamarock and Klemp in Mon Weather Rev 122:2623-2630, 1994), and the linear hydrostatic mountain waves of (Bonaventura in J Comput Phys 158:186-213, 2000).

  19. Approximate and Conditional Teleportation of an Unknown Atomic State with Dissipative Jaynes-Cummings Model

    Institute of Scientific and Technical Information of China (English)

    ZHOU Yu-Rong; CHEN Chang-Yong; PAN Hui-Mei; GUO Feng; PANG Xiao-Feng

    2008-01-01

    A scheme for approximately and conditionally teleporting an unknown atomic state in dissipative cavity QED is proposed. It is the extension of the scheme of [Phys. Rev. A 69 (2004) 064302], where the cavity mode decay has not been considered and only a time point of system evolution and the corresponding fidelity implementing the teleportation are given. In fact, the cavity mode decay exists really and must be delt with. In this paper, we investigate the influence from the cavity mode decay on the implementation of the approximate and conditional teleportation by means of the dissipative Jaynes Cummings model and then show the analytical expression of the fidelity of realization of the teleportation, Alternatively, our scheme does not involve an additional atom, only requiring two atoms and one single-mode cavity.

  20. First stage of LISA data processing. II. Alternative filtering dynamic models for LISA

    Science.gov (United States)

    Wang, Yan; Heinzel, Gerhard; Danzmann, Karsten

    2015-08-01

    Space-borne gravitational wave detectors, such as (e)LISA, are designed to operate in the low-frequency band (mHz to Hz), where there is a variety of gravitational wave sources of great scientific value [arXiv:1305.5720 and S. Babak et al., Classical Quantum Gravity 28, 114001 (2011)]. To achieve the extraordinary sensitivity of these detectors, the precise synchronization of the clocks on the separate spacecraft and the accurate determination of the interspacecraft distances are important ingredients. In our previous paper [Y. Wang et al., Phys. Rev. D 90, 064016 (2014)], we have described a hybrid-extend Kalman filter with a full state vector to do this job. In this paper, we explore several different state vectors and their corresponding (phenomenological) dynamic models to reduce the redundancy in the full state vector, to accelerate the algorithm, and to make the algorithm easily extendable to more complicated scenarios.

  1. First stage of LISA data processing II: Alternative filtering dynamic models for LISA

    CERN Document Server

    Wang, Yan; Danzmann, Karsten

    2015-01-01

    Space-borne gravitational wave detectors, such as (e)LISA, are designed to operate in the low-frequency band (mHz to Hz), where there is a variety of gravitational wave sources of great scientific value. To achieve the extraordinary sensitivity of these detector, the precise synchronization of the clocks on the separate spacecraft and the accurate determination of the interspacecraft distances are important ingredients. In our previous paper (Phys. Rev. D 90, 064016 [2014]), we have described a hybrid-extend Kalman filter with a full state vector to do this job. In this paper, we explore several different state vectors and their corresponding (phenomenological) dynamic models, to reduce the redundancy in the full state vector, to accelerate the algorithm, and to make the algorithm easily extendable to more complicated scenarios.

  2. Kosterlitz-Thouless and Potts transitions in a generalized XY model.

    Science.gov (United States)

    Canova, Gabriel A; Levin, Yan; Arenzon, Jeferson J

    2014-01-01

    We present extensive numerical simulations of a generalized XY model with nematic-like terms recently proposed by Poderoso et al. [ Phys. Rev. Lett. 106 067202 (2011)]. Using finite size scaling and focusing on the q=3 case, we locate the transitions between the paramagnetic (P), the nematic-like (N), and the ferromagnetic (F) phases. The results are compared with the recently derived lower bounds for the P-N and P-F transitions. While the P-N transition is found to be very close to the lower bound, the P-F transition occurs significantly above the bound. Finally, the transition between the nematic-like and the ferromagnetic phases is found to belong to the three-states Potts universality class.

  3. CTL Responses to Regulatory Proteins Tat and Rev in HIV-1 B'/C Virus-Infected Individuals

    Institute of Scientific and Technical Information of China (English)

    MING-MING JIA; KUN-XUE HONG; JIAN-PING CHEN; HONG-WEI LIU; SHA LIU; XIAO-QING ZHANG; HONG-JING ZHAO; YI-MING SHAO

    2008-01-01

    To characterize HIV-1 specific CTL responses to regulatory proteins Tat and Rev in HIV-B'/C vires-infected ART-naive individuals. Methods HIV-1-specific CTL responses were analyzed by IFN-γ ELISPOT assay using overlapping peptides spanning the consensus sequences of HIV-1 clade C Tat and Rev proteins. Statistical analysis and graphical presentation were performed using SIGMAPLOT 10.0 and SIGMASTAT 3.5. For samples with a positive response, the magnitude of CTL responses was compared between HIV-1 C proteins by Wilcoxon rank sum test, and the significance threshold was P<0.05. Results Tat and Rev were frequently recognized, with 23% and 52% of the tested individuals having detectable responses to these proteins, respectively. Several immunodominant regions were detected in Rev. No significant correlation was observed between the magnitude and breadth of CTL responses to regulatory proteins and the control of virus replication in this study. Conclusion Tat and Rev can serve as targets for HIV-1-specific CTL, and several immunodominant regions are detectable in Rev. Further characterization of epitopes and their role in virus control may shed light on pathogenesis of HIV-1 natural infection and also be useful for the design and testing of candidate vaccines.

  4. Spherical systems in models of nonlocally corrected gravity

    CERN Document Server

    Bronnikov, K A

    2009-01-01

    The properties of static, spherically symmetric configurations are considered in the framework of two models of nonlocally corrected gravity, suggested in S. Deser and R. Woodard., Phys. Rev. Lett. 663, 111301 (2007), and S. Capozziello et al., Phys. Lett. B 671, 193 (2009). For the first case, where the Lagrangian of nonlocal origin represents a scalar-tensor theory with two massless scalars, an explicit condition is found under which both scalars are canonical (non-phantom). If this condition does not hold, one of the fields exhibits a phantom behavior. Scalar-vacuum configurations then behave in a manner known for scalar-tensor theories. In the second case, the Lagrangian of nonlocal origin exhibits a scalar field interacting with the Gauss-Bonnet (GB) invariant and contains an arbitrary scalar field potential. It is found that the GB term, in general, leads to violation of the well-known no-go theorems valid for minimally coupled scalar fields in general relativity. It is shown, however, that some configu...

  5. A BAC clone of MDV strain GX0101 with REV-LTR integration retained its pathogenicity

    Institute of Scientific and Technical Information of China (English)

    SUN AiJun; LAWRENCE Petherbridge; ZHAO YuGuang; LI YanPeng; NAIR Venugopal K; CUI ZhiZhong

    2009-01-01

    The complete genome of Marek's disease virus (MDV) strain GX0101,which was integrated with the LTR sequences of REV,was cloned in Escherichia coli as a bacterial artificial chromosome (BAC).BAC vector sequences were introduced into the US2 locus of the MDV genome by homologous recombination.The viral DNA containing the BAC vector was used to transform Escherichia coli strain of DH10B.Then the recombinant virus was successfully rescued by transfection of the recombinant BAC DNA into primary chicken embryo fibroblast (CEF).This BAC viral clone was named bac-GX0101.When the reconstituted virus was inoculated into 1-day-old birds,visceral tumors could be detected as early as 62 d post infection.There was no difference in growth ability and pathogenicity to birds between the BAC derived virus and its parental virus.The BAC derived virus maintained its oncogenicity and immunosuppressive effects.In conclusion,the complete genome of GX0101 strain was successfully cloned into BAC and the infectious clone was rescued.With the powerful BAC manipulation system,the infectious clone will provide a useful tool for further understanding the functional roles of the inserted REV-LTR sequence in the GX0101 strain of MDV.

  6. High amplitude phase resetting in rev-erbalpha/per1 double mutant mice.

    Directory of Open Access Journals (Sweden)

    Corinne Jud

    Full Text Available Over time, organisms developed various strategies to adapt to their environment. Circadian clocks are thought to have evolved to adjust to the predictable rhythms of the light-dark cycle caused by the rotation of the Earth around its own axis. The rhythms these clocks generate persist even in the absence of environmental cues with a period of about 24 hours. To tick in time, they continuously synchronize themselves to the prevailing photoperiod by appropriate phase shifts. In this study, we disrupted two molecular components of the mammalian circadian oscillator, Rev-Erbalpha and Period1 (Per1. We found that mice lacking these genes displayed robust circadian rhythms with significantly shorter periods under constant darkness conditions. Strikingly, they showed high amplitude resetting in response to a brief light pulse at the end of their subjective night phase, which is rare in mammals. Surprisingly, Cry1, a clock component not inducible by light in mammals, became slightly inducible in these mice. Taken together, Rev-Erbalpha and Per1 may be part of a mechanism preventing drastic phase shifts in mammals.

  7. Modeling for Sensor Evaluation in Underwater UXO Test Beds, Rev 3

    Science.gov (United States)

    2008-01-11

    Autonomous Underwater Vehicle BBSAS – Broad-Band SAS BOSS – Buried Object Scanning Sonar BU – Boston University FAU – Florida Atlantic...Ted Clem (NSWCPC) and Dr. Steve Schock ( FAU ), who led the teams that collected and analyzed data from UXO surrogates in St Andrews Bay as part of...frequency band than is practical with buried hydrophone arrays used to carry out time-of-flight measurements. When used in conjunction with time-of

  8. Hydrogen adsorption strength and sites in the metal organic framework MOF5: Comparing experiment and model calculations

    Science.gov (United States)

    Mulder, F. M.; Dingemans, T. J.; Schimmel, H. G.; Ramirez-Cuesta, A. J.; Kearley, G. J.

    2008-07-01

    Hydrogen adsorption in porous, high surface area, and stable metal organic frameworks (MOF's) appears a novel route towards hydrogen storage materials [N.L. Rosi, J. Eckert, M. Eddaoudi, D.T. Vodak, J. Kim, M. O'Keeffe, O.M. Yaghi, Science 300 (2003) 1127; J.L.C. Rowsell, A.R. Millward, K. Sung Park, O.M. Yaghi, J. Am. Chem. Soc. 126 (2004) 5666; G. Ferey, M. Latroche, C. Serre, F. Millange, T. Loiseau, A. Percheron-Guegan, Chem. Commun. (2003) 2976; T. Loiseau, C. Serre, C. Huguenard, G. Fink, F. Taulelle, M. Henry, T. Bataille, G. Férey, Chem. Eur. J. 10 (2004) 1373]. A prerequisite for such materials is sufficient adsorption interaction strength for hydrogen adsorbed on the adsorption sites of the material because this facilitates successful operation under moderate temperature and pressure conditions. Here we report detailed information on the geometry of the hydrogen adsorption sites, based on the analysis of inelastic neutron spectroscopy (INS). The adsorption energies for the metal organic framework MOF5 equal about 800 K for part of the different sites, which is significantly higher than for nanoporous carbon materials (˜550 K) [H.G. Schimmel, G.J. Kearley, M.G. Nijkamp, C.T. Visser, K.P. de Jong, F.M. Mulder, Chem. Eur. J. 9 (2003) 4764], and is in agreement with what is found in first principles calculations [T. Sagara, J. Klassen, E. Ganz, J. Chem. Phys. 121 (2004) 12543; F.M. Mulder, T.J. Dingemans, M. Wagemaker, G.J. Kearley, Chem. Phys. 317 (2005) 113]. Assignments of the INS spectra is realized using comparison with independently published model calculations [F.M. Mulder, T.J. Dingemans, M. Wagemaker, G.J. Kearley, Chem. Phys. 317 (2005) 113] and structural data [T. Yildirim, M.R. Hartman, Phys. Rev. Lett. 95 (2005) 215504].

  9. Simulating Streamer Inception From Hydrometeors as a Stochastic Process with a Particle-Based Model

    Science.gov (United States)

    Rutjes, C.; Dubinova, A.; Ebert, U.; Buitink, S.; Scholten, O.; Trinh, G. T. N.

    2016-12-01

    In thunderstorms, streamers (as a precursor for lightning) can be initiated from hydrometeors (droplets, graupel, ice needles, etc.) which enhance the thundercloud electric field to values above electric breakdown; and initial electrons may come from extensive air showers [1]. Typically, streamer inception from hydrometeors is theoretically studied with deterministic fluid simulations (i.e. drift-diffusion-reaction coupled with Poisson), see [1, 2, 3] and references therein. However, electrons will only multiply in the area above breakdown, which is of the order of a cubic millimeter for hydrometeors of sub-centimeter scale. Initial electron densities, even in extreme extensive air showers events, do not exceed 10 per cubic millimeter. Hence only individual electron avalanches - with their intrinsically random nature - are entering the breakdown area sequentially. On these scales, a deterministic fluid description is thus not valid. Ideally one would do fully 3D particle simulations, like in [4], but they are computationally too costly for a parameter study with many geometries. Therefore, we developed a new stochastic particle-based model to study the behavior of the system described above. We do not follow individual electrons but complete electron avalanches. We have calculated the probability distribution of streamer inception for various hydrometeor geometries, which potentially makes it possible - when having accurate enough meteorological data - to predict where, when and how many streamers in a thundercloud occur. Besides in geophysics, the new model is also important in the context of high voltage technology, and it gives new insight in the validity of the Meek-criterion for discharge inception. [1] Dubinova et al. 2015. Phys. Rev. Lett. 115(1), 015002.[2] Liu et al. 2012. Phys. Rev. Lett. 109(2), 025002.[3] Babich et al. 2016. J. Geophys. Res. Atmos. 121, 6393-6403.[4] Teunissen, T. & Ebert, U. 2016. Plasma Sources Sci. Technol. 25(4), 044005.

  10. Response to "Comment on ‘Electric Multipole Moments for Some First-Row Diatomic Hydride Molecules' [Commun. Theor. Phys. 38 (2002) 256]"

    Institute of Scientific and Technical Information of China (English)

    Metin Orbay; Telhat Ozdogan

    2003-01-01

    The comment of Guseinov is irrelevant and also unjust. In contrast to his comment, we show that theobtained electric multipole moment values for some first-row diatomic molecules are original and better than his values(I.I. Guseinov, E. Akin, and A.M. Rzaeva, J. Mol. Struct. (Theochem) 453 (1998) 163) with respect to Hartree-Fockvalues. Moreover, it must be noted that all the formulas are cited in our paper (M. Orbay and T. Ozdogan, Commun.Theor. Phys. (Beijing, China) 35 (2001) 585) and corrigendum (M. Orbay and T. Ozdogan, Commun. Theor. Phys.(Beijing, China) 37 (2002) 768).

  11. A new crossover sine model based on trigonometric model and its application to the crossover lattice equation of state

    Science.gov (United States)

    Lee, Yongjin; Shin, Moon Sam; Kim, Hwayong

    2008-12-01

    In this study, a new crossover sine model (CSM) n was developed from a trigonometric model [M. E. Fisher, S. Zinn, and P. J. Upton, Phys. Rev. B 59, 14533 (1999)]. The trigonometric model is a parametric formulation model that is used to represent the thermodynamic variables near a critical point. Although there are other crossover models based on this trigonometric model, such as the CSM and the analytical sine model, which is an analytic formulation of the CSM, the new sine model (NSM) employs a different approach from these two models in terms of the connections between the parametric variables of the trigonometric model and thermodynamic variables. In order to test the performance of the NSM, the crossover lattice equation of state [M. S. Shin, Y. Lee, and H. Kim, J. Chem. Thermodyn. 40, 174 (2008)] was applied using the NSM for correlations of various pure fluids and fluid mixtures. The results showed that over a wide range of states, the crossover lattice fluid (xLF)/NSM yields the saturated properties of pure fluids and the phase behavior of binary mixtures more accurately than the original lattice equation of state. Moreover, a comparison with the crossover lattice equation of state using the CSM (xLF/CSM) showed that the new model presents good correlation results that are comparable to the xLF/CSM.

  12. The structural basis of gas-responsive transcription by the human nuclear hormone receptor REV-ERBbeta.

    Directory of Open Access Journals (Sweden)

    Keith I Pardee

    2009-02-01

    Full Text Available Heme is a ligand for the human nuclear receptors (NR REV-ERBalpha and REV-ERBbeta, which are transcriptional repressors that play important roles in circadian rhythm, lipid and glucose metabolism, and diseases such as diabetes, atherosclerosis, inflammation, and cancer. Here we show that transcription repression mediated by heme-bound REV-ERBs is reversed by the addition of nitric oxide (NO, and that the heme and NO effects are mediated by the C-terminal ligand-binding domain (LBD. A 1.9 A crystal structure of the REV-ERBbeta LBD, in complex with the oxidized Fe(III form of heme, shows that heme binds in a prototypical NR ligand-binding pocket, where the heme iron is coordinately bound by histidine 568 and cysteine 384. Under reducing conditions, spectroscopic studies of the heme-REV-ERBbeta complex reveal that the Fe(II form of the LBD transitions between penta-coordinated and hexa-coordinated structural states, neither of which possess the Cys384 bond observed in the oxidized state. In addition, the Fe(II LBD is also able to bind either NO or CO, revealing a total of at least six structural states of the protein. The binding of known co-repressors is shown to be highly dependent upon these various liganded states. REV-ERBs are thus highly dynamic receptors that are responsive not only to heme, but also to redox and gas. Taken together, these findings suggest new mechanisms for the systemic coordination of molecular clocks and metabolism. They also raise the possibility for gas-based therapies for the many disorders associated with REV-ERB biological functions.

  13. The structural basis of gas-responsive transcription by the human nuclear hormone receptor REV-ERBbeta.

    Science.gov (United States)

    Pardee, Keith I; Xu, Xiaohui; Reinking, Jeff; Schuetz, Anja; Dong, Aiping; Liu, Suya; Zhang, Rongguang; Tiefenbach, Jens; Lajoie, Gilles; Plotnikov, Alexander N; Botchkarev, Alexey; Krause, Henry M; Edwards, Aled

    2009-02-24

    Heme is a ligand for the human nuclear receptors (NR) REV-ERBalpha and REV-ERBbeta, which are transcriptional repressors that play important roles in circadian rhythm, lipid and glucose metabolism, and diseases such as diabetes, atherosclerosis, inflammation, and cancer. Here we show that transcription repression mediated by heme-bound REV-ERBs is reversed by the addition of nitric oxide (NO), and that the heme and NO effects are mediated by the C-terminal ligand-binding domain (LBD). A 1.9 A crystal structure of the REV-ERBbeta LBD, in complex with the oxidized Fe(III) form of heme, shows that heme binds in a prototypical NR ligand-binding pocket, where the heme iron is coordinately bound by histidine 568 and cysteine 384. Under reducing conditions, spectroscopic studies of the heme-REV-ERBbeta complex reveal that the Fe(II) form of the LBD transitions between penta-coordinated and hexa-coordinated structural states, neither of which possess the Cys384 bond observed in the oxidized state. In addition, the Fe(II) LBD is also able to bind either NO or CO, revealing a total of at least six structural states of the protein. The binding of known co-repressors is shown to be highly dependent upon these various liganded states. REV-ERBs are thus highly dynamic receptors that are responsive not only to heme, but also to redox and gas. Taken together, these findings suggest new mechanisms for the systemic coordination of molecular clocks and metabolism. They also raise the possibility for gas-based therapies for the many disorders associated with REV-ERB biological functions.

  14. Estimation of coupling between oscillators from short time series via phase dynamics modeling: limitations and application to EEG data

    CERN Document Server

    Smirnov, D A; Velazquez, J L P; Wennberg, R A; Bezruchko, B P

    2005-01-01

    We demonstrate in numerical experiments that estimators of strength and directionality of coupling between oscillators based on modeling of their phase dynamics [D.A. Smirnov and B.P. Bezruchko, Phys. Rev. E 68, 046209 (2003)] are widely applicable. Namely, although the expressions for the estimators and their confidence bands are derived for linear uncoupled oscillators under the influence of independent sources of Gaussian white noise, they turn out to allow reliable characterization of coupling from relatively short time series for different properties of noise, significant phase nonlinearity of the oscillators, and non-vanishing coupling between them. We apply the estimators to analyze a two-channel human intracranial epileptic electroencephalogram (EEG) recording with the purpose of epileptic focus localization.

  15. Rectangular model of a ballistic spin interferometer in (001) InGaAs/InAlAs quantum wells

    Science.gov (United States)

    Koga, Takaaki; Faniel, S.; Mineshige, S.; Mastuura, T.; Sekine, Y.

    2010-01-01

    We report an unambiguous detection of the crytalline anisotropy of the spin-orbit interaction in (001) InAlAs/InGaAs/InAlAs quantum wells using nanofabricated rectangular loop arrays, where the sides of the constituent loops are aligned along either the [110] or [ 1 1 ¯ 0] crystallographic axis. The fabrication and measurements were performed on the epi-wafer samples whose spin properties were characterized previously [Koga et al. Phys. Rev. Lett 89 (2002) 046801]. We find that the experimentally observed spin interference patterns - the amplitude modulation of the Al'tshuler-Aronov-Spivak oscillations as a function of the gate voltage - are in good agreement with the results of the spin interferometer model extended for rectangular loops and including both the Rashba and Dresselhaus spin-orbit interactions.

  16. Dynamic behavior of thermoacoustic combustion oscillations in a lean premixed gas-turbine model combustor with and without active control

    Science.gov (United States)

    Tsujimoto, Ryosuke; Domen, Shohei; Okuno, Yuta; Nakagaki, Yoshitake; Gotoda, Hiroshi

    2014-11-01

    We experimentally study the dynamic behavior of thermoacoustic combustion oscillations in a laboratory-scale lean premixed gas-turbine model combustor with and without active control. We adopt the delayed feedback control method based on the concept of chaos control to suppress thermoacoustic combustion oscillations. The unstable periodic orbits in the attractor of uncontrolled thermoacoustic combustion oscillations are led to the desired orbits with a small diameter of the attractor when the perturbation is switched on, resulting in the notable suppression of thermoacoustic combustion oscillations. Color-recurrence plots (Gotoda et al., Phys. Rev. E 89, 022910 (2014)) are used for characterizing the complexity of the combustion state with and without delayed feedback control.

  17. Model of non-stationary, inhomogeneous turbulence

    Science.gov (United States)

    Bragg, Andrew D.; Kurien, Susan; Clark, Timothy T.

    2017-02-01

    We compare results from a spectral model for non-stationary, inhomogeneous turbulence (Besnard et al. in Theor Comp Fluid Dyn 8:1-35, 1996) with direct numerical simulation (DNS) data of a shear-free mixing layer (SFML) (Tordella et al. in Phys Rev E 77:016309, 2008). The SFML is used as a test case in which the efficacy of the model closure for the physical-space transport of the fluid velocity field can be tested in a flow with inhomogeneity, without the additional complexity of mean-flow coupling. The model is able to capture certain features of the SFML quite well for intermediate to long times, including the evolution of the mixing-layer width and turbulent kinetic energy. At short-times, and for more sensitive statistics such as the generation of the velocity field anisotropy, the model is less accurate. We propose two possible causes for the discrepancies. The first is the local approximation to the pressure-transport and the second is the a priori spherical averaging used to reduce the dimensionality of the solution space of the model, from wavevector to wavenumber space. DNS data are then used to gauge the relative importance of both possible deficiencies in the model.

  18. Model of reversible vesicular transport with exclusion

    Science.gov (United States)

    Bressloff, Paul C.; Karamched, Bhargav R.

    2016-08-01

    A major question in neurobiology concerns the mechanics behind the motor-driven transport and delivery of vesicles to synaptic targets along the axon of a neuron. Experimental evidence suggests that the distribution of vesicles along the axon is relatively uniform and that vesicular delivery to synapses is reversible. A recent modeling study has made explicit the crucial role that reversibility in vesicular delivery to synapses plays in achieving uniformity in vesicle distribution, so called synaptic democracy (Bressloff et al 2015 Phys. Rev. Lett. 114 168101). In this paper we generalize the previous model by accounting for exclusion effects (hard-core repulsion) that may occur between molecular motor-cargo complexes (particles) moving along the same microtubule track. The resulting model takes the form of an exclusion process with four internal states, which distinguish between motile and stationary particles, and whether or not a particle is carrying vesicles. By applying a mean field approximation and an adiabatic approximation we reduce the system of ODEs describing the evolution of occupation numbers of the sites on a 1D lattice to a system of hydrodynamic equations in the continuum limit. We find that reversibility in vesicular delivery allows for synaptic democracy even in the presence of exclusion effects, although exclusion does exacerbate nonuniform distributions of vesicles in an axon when compared with a model without exclusion. We also uncover the relationship between our model and other models of exclusion processes with internal states.

  19. Experimental test of state-independent quantum contextuality of an indivisible quantum system

    Science.gov (United States)

    Huang, Yun-Feng; Li, Meng; Cao, Dong-Yang; Zhang, Chao; Zhang, Yong-Sheng; Liu, Bi-Heng; Li, Chuan-Feng; Guo, Guang-Can

    2013-05-01

    We report a state-independent experimental test of quantum contextuality of a single-photon qutrit. The experimental results demonstrate violations of an inequality originally formulated by Yu and Oh [Phys. Rev. Lett.PRLTAO0031-900710.1103/PhysRevLett.108.030402 108, 030402 (2012)] and further optimized by Cabello [Phys. Rev. APLRAAN1050-294710.1103/PhysRevA.85.032108 85, 032108 (2012)]; this inequality is satisfied by all noncontextual hidden variable models and is violated by all qutrit states. Our experiment shows quantum contextuality of this nature in a most fundamental way: A way that is independent of state and unrelated to entanglement.

  20. Comment on ``Barut-Girardello and Klauder-Perelomov coherent states for the Kravchuk functions'' [J. Math. Phys. 48, 112106 (2007)

    Science.gov (United States)

    Fakhri, H.; Dehghani, A.

    2008-04-01

    We call attention to the misconstructions in a paper recently published in this journal [A. Chenaghlou and O. Faizy, J. Math. Phys. 48, 112106 (2007)]. It is shown that the constructed Barut-Girardello coherent states are problematic from the view points of the definition and the measure. The claimed coherencies for the Kravchuk functions cannot actually exist.