WorldWideScience

Sample records for model palle rasmussen

  1. Erik Rasmussen

    DEFF Research Database (Denmark)

    Lippert-Rasmussen, Kasper

    første generationer af cand. scient. pol.’er og med til at skole disse i den videnskabelige værdirelativisme, strukturfunktionalismen og David Easton’s opfattelse af politik og det politiske system. I sine senere år søgte Rasmussen især at kaste et kritisk lys over, hvad han anså for at være sin samtids...

  2. Rasmussen 脑炎%Rasmussen encephalitis

    Institute of Scientific and Technical Information of China (English)

    吴家骅

    2006-01-01

    @@ 1958年加拿大蒙特利尔神经研究所的Theadore Rasmussen 及同事 Olszewski和 Lloyd-Smith一起以"慢性限局性脑炎引起的局灶性发作"为题报告3个病例[1] .至上世纪 80 年代,此概念已被多数学者所接受,但也不乏争议,因为由符合诊断条件病例的脑组织并未分离出病毒.有的文献将Rasmussen脑炎(RE)称为Rasmussen 综合征(RS),在 2001 年国际抗癫NFDA1联盟(ILAE)关于癫NFDA1及癫NFDA1综合征分类举例中归类于"症状性(或可能是症状性)局灶性癫NFDA1",属于新皮层区癫NFDA1的一种[2].2005年 Bien 等在Brain杂志上发表欧洲学者对此病的共识时仍称RE[3].现介绍如下.

  3. Multiphasic presentation of Rasmussen's encephalitis

    NARCIS (Netherlands)

    A. Avbersek; A. Miserocchi; A.W. McEvoy; A.V. Patel; E. Aronica; I. Blumcke; T.S. Jacques; J. Acheson; M. Thom; S.M. Sisodiya

    2015-01-01

    Rasmussen's encephalitis is a rare, chronic inflammatory disorder of unknown cause, characterised by drug-resistant focal epilepsy that may rarely present in adolescence or adulthood. We present a case of Rasmussen's encephalitis with prominent recurrent fluctuation in symptoms and well-documented f

  4. Electrophysiological findings in Rasmussen's syndrome.

    Science.gov (United States)

    Gündüz, Ayşegül; Kızıltan, Meral E; Coşkun, Tülin; Delil, Şakir; Yeni, Naz; Özkara, Çiğdem

    2016-03-01

    Rasmussen syndrome is a rare, inflammatory and probably autoimmune disease presenting with epilepsia partialis continua which is generally in the form of myoclonic jerks and involves the upper extremities with or without head involvement. We sought to demonstrate the electrophysiological features in patients with Rasmussen syndrome. We performed continuous electrophysiological recordings of involuntary movement, as well as recordings of startle responses and long latency reflex in three patients with a diagnosis of Rasmussen syndrome. Positive and negative myoclonus were recorded. Startle responses were found to be suppressed. However, long latency reflexes were high in amplitude and one patient even had a C reflex. Stimulus-sensitive positive and negative cortical myoclonus are typical in epilepsia partialis continua of Rasmussen syndrome and degeneration of brainstem and reticulospinal pathways may develop in Rasmussen syndrome.

  5. Rasmussen's legacy: A paradigm change in engineering for safety.

    Science.gov (United States)

    Leveson, Nancy G

    2017-03-01

    This paper describes three applications of Rasmussen's idea to systems engineering practice. The first is the application of the abstraction hierarchy to engineering specifications, particularly requirements specification. The second is the use of Rasmussen's ideas in safety modeling and analysis to create a new, more powerful type of accident causation model that extends traditional models to better handle human-operated, software-intensive, sociotechnical systems. Because this new model has a formal, mathematical foundation built on systems theory (as was Rasmussen's original model), new modeling and analysis tools become possible. The third application is to engineering hazard analysis. Engineers have traditionally either omitted human from consideration in system hazard analysis or have treated them rather superficially, for example, that they behave randomly. Applying Rasmussen's model of human error to a powerful new hazard analysis technique allows human behavior to be included in engineering hazard analysis. Copyright © 2016 Elsevier Ltd. All rights reserved.

  6. Wexler's Great Smoke Pall: a chemistry-climate model analysis of a singularly large emissions pulse

    Science.gov (United States)

    Field, R. D.; Voulgarakis, A.

    2011-12-01

    We model the effects of the smoke plume from what was arguably the largest forest fire in recorded history. The Chinchaga fire burned continuously during the summer of 1950 in northwestern Canada during a very dry fire season. On September 22nd, the fire made a major advance, burning an area of approximately 1400 km2. Ground and aircraft observations showed that from September 22 to 28, the smoke plume from the emissions pulse travelled over northern Canada, southward over the Great Lakes region and eastern US, across the Atlantic, and to Western Europe. Over the Great Lakes region, the plume remained thick enough to create twilight conditions in the mid-afternoon, and was estimated to have caused a 4 oC cooling at the surface. While many instances of long-range transport of wildfire emissions have been detected over the past decade, we know of no other wildfire which created such an acute effect on downward shortwave radiation at such a long distance. As a result, the fire was an important analogue event used in estimating the effects of a nuclear winter. Simulations with the nudged version of the GISS chemistry-climate model accurately capture the long-range transport pattern of the smoke emissions in the free-troposphere. The timing and location of aircraft observations of the plume over the eastern US, North Atlantic and the United Kingdom were well-matched to modeled anomalies of CO and aerosol optical depth. Further work will examine the model's ability to create twilight conditions during the day, and to provide an estimate of the consequent cooling effects at the surface from this remarkable emissions pulse.

  7. Rasmussen's syndrome and its treatment by hemispherectomy

    Institute of Scientific and Technical Information of China (English)

    杨忠旭; 栾国明

    2004-01-01

    @@ Rasmussen syndrome is a special disease which mainly affects one side of the cerebral himsphere and is complicated by intractable epilepsy. This disease is seldom encountered. We treated satisfactorily cases of Rasmussen syndrome with modified himspherectomy.

  8. Erik Rasmussen, Niels Bohr og Værdirelativismen - i anledning af Kasper Lippert-Rasmussens bog om Erik Rasmussen

    DEFF Research Database (Denmark)

    Ougaard, Morten

    2015-01-01

    En svaghed ved Kasper Lippert-Rasmussens i øvrigt udmærkede bog om Erik Rasmussen er, at den forbigår den sene Rasmussens bog om komplementaritet og statskundskab. Bogen var vigtig for Rasmussen, og den bør indgå i hans faglige eftermæle. Den rummer videnskabsteoretiske argumenter af stor relevans...... ikke mindst forholdet mellem normative og kognitive udsagn. Efter mødet med Niels Bohrs filosofi står Rasmussens værdirelativisme både skarpere og stærkere end før, og Kasper Lippert-Rasmussens karakteristik af denne position som et ubegrundet dogme i dansk politologi er ikke overbevisende....

  9. Present status of rasmussen encephalitis

    Institute of Scientific and Technical Information of China (English)

    Yuguang Guan; Tianfu Li; Guoming Luan

    2014-01-01

    Rasmussen's encephalitis is a rare progressive encephalitis that results in intractable seizures,cognitive decline, and hemiparesis.The affected hemispheres of RE patients are typically unilateral.There is no conclusive evidence elucidating RE etiology.To date,no antiepileptic drug has been demonstrated to be effective for controlling the disease or stopping its pro-gression.Immunoglobulins and high doses of steroids may be transiently helpful in some patients at an early stage.Only hemi-spherectomy are useful methods to control seizures in RE patients.

  10. Theodore Brown Rasmussen (1910-2002).

    Science.gov (United States)

    Stahnisch, Frank W; Nakashima, Amy S

    2013-10-01

    Dr. Theodore Rasmussen was a Canadian neurosurgeon, neurologist, and neuropathologist who primarily specialized in the treatment and histopathology of epilepsy. In addition to his eponym, "Rasmussen syndrome", a chronic form of encephalitis accompanied by epilepsy, his contributions included the refinement of neurosurgical techniques, thoroughly cataloguing outcomes following surgery for epilepsy, and cortical mapping studies conducted with Dr. Wilder Penfield.

  11. Theodore Brown Rasmussen (1910–2002)

    OpenAIRE

    2013-01-01

    Dr. Theodore Rasmussen was a Canadian neurosurgeon, neurologist, and neuropathologist who primarily specialized in the treatment and histopathology of epilepsy. In addition to his eponym, “Rasmussen syndrome”, a chronic form of encephalitis accompanied by epilepsy, his contributions included the refinement of neurosurgical techniques, thoroughly cataloguing outcomes following surgery for epilepsy, and cortical mapping studies conducted with Dr. Wilder Penfield.

  12. A Museum for Palle Nielsen

    DEFF Research Database (Denmark)

    Thorborg, Christoffer

    2016-01-01

    The present project attempts to articulate architecturally the psychic content in the danish graphic artist and draftsman Palle Nielsen's oeuvre. The museum inscribes itself within the city of Copenhagen as a part of it, but simultaneously establishes a taut vacuum between the city's buildings, t......, thereby setting these existing, surrounding monumental buildings in relief. The interior of the museum manifests itself as a dramatic, labyrinthine course of empty spaces, within which the visitor is deprived of contact with the city, and potentially loses his or her sense of place....

  13. Erik Rasmussen, Niels Bohr og Værdirelativismen - i anledning af Kasper Lippert-Rasmussens bog om Erik Rasmussen

    DEFF Research Database (Denmark)

    Ougaard, Morten

    2015-01-01

    , ikke mindst med hensyn til værdirelativismen. Rasmussen viser, at komplementaritetsbegrebet i Bohrs vigtige men oversete filosofi kan bidrage væsentligt til at afklare teoretisk-metodiske problemer i statskundskab, herunder forholdet mellem struktur og handling og mellem mikro- og makroanalyse, samt...... ikke mindst forholdet mellem normative og kognitive udsagn. Efter mødet med Niels Bohrs filosofi står Rasmussens værdirelativisme både skarpere og stærkere end før, og Kasper Lippert-Rasmussens karakteristik af denne position som et ubegrundet dogme i dansk politologi er ikke overbevisende....

  14. Putaminal involvement in Rasmussen encephalitis

    Energy Technology Data Exchange (ETDEWEB)

    Rajesh, Bhagavatheeswaran; Ashalatha, Radhakrishnan [Sree Chitra Tirunal Institute for Medical Sciences and Technology, Department of Neurology, Trivandrum, Kerala (India); Kesavadas, Chandrasekharan; Thomas, Bejoy [Sree Chitra Tirunal Institute for Medical Sciences and Technology, Department of Imaging Sciences and Interventional Radiology, Trivandrum, Kerala (India)

    2006-08-15

    Rasmussen encephalitis (RE) is a rare devastating disease of childhood causing progressive neurological deficits and intractable seizures, typically affecting one hemisphere. Characteristic MRI features include progressive unihemispheric focal cortical atrophy and grey- or white-matter high-signal changes and basal ganglion involvement, particularly of the caudate nucleus. To analyse the pattern of involvement of different brain structures in a series of patients with RE and to attempt clinical correlation. We reviewed the medical records and neuroimaging data of 12 patients diagnosed with RE satisfying the European Consensus Statement diagnostic criteria. The disease manifested as seizures in all patients and was refractory; epilepsia partialis continua was a notable feature (nine patients). Hemiparesis of varying grades was noted in all but one patient; none had extrapyramidal signs. Neuroimaging showed cortical involvement in the insular/periinsular regions in 11 patients. Caudate atrophy was noted in ten patients. Putaminal atrophy was seen in nine patients, six of whom had additional hyperintense signal changes. Our study highlights frequent putaminal atrophy and signal changes in RE, which suggests a more extensive basal ganglion involvement than emphasized previously. Recognition of putaminal changes may be a useful additional tool in the radiological diagnosis of RE. (orig.)

  15. Rasmussen's encephalitis presenting as focal cortical dysplasia

    Directory of Open Access Journals (Sweden)

    D.J. O'Rourke

    2014-01-01

    Full Text Available Rasmussen's encephalitis is a rare syndrome characterized by intractable seizures, often associated with epilepsia partialis continua and symptoms of progressive hemispheric dysfunction. Seizures are usually the hallmark of presentation, but antiepileptic drug treatment fails in most patients and is ineffective against epilepsia partialis continua, which often requires surgical intervention. Co-occurrence of focal cortical dysplasia has only rarely been described and may have implications regarding pathophysiology and management. We describe a rare case of dual pathology of Rasmussen's encephalitis presenting as a focal cortical dysplasia (FCD and discuss the literature on this topic.

  16. Theodore Brown Rasmussen (1910-2002): epilepsy surgeon, scientist, and teacher.

    Science.gov (United States)

    Feindel, William

    2003-03-01

    Theodore Brown Rasmussen succeeded Wilder Penfield as director of the Montreal Neurological Institute (MNI) and held this post from 1960 to 1972. During his career, Rasmussen probably performed more operations for epilepsy than any other surgeon of his time; he became the foremost authority in this field. His meticulous follow-up analyses of the MNI seizure series provided substantial evidence for the success of surgery in the treatment of focal epilepsy. In addition, he made significant contributions to surgery of the pituitary gland for control of cancer, treatment of cerebral and spinal tumors, application of the intracarotid Amytal test for lateralization of speech and memory function, and characterization and treatment of epilepsy accompanied by chronic encephalitis, now referred to as Rasmussen syndrome. His painstaking attention to surgical details as well as his insistence on close monitoring of patient care and critical scrutiny of clinical results marked him as an outstanding teacher and role model for young neurosurgeons and neuroscientists.

  17. Anders Fogh Rasmussen : Riigi suurus sõltub poliitikutest / Anders Fogh Rasmussen ; interv. Marianne Mikko

    Index Scriptorium Estoniae

    Rasmussen, Anders Fogh

    2003-01-01

    Taani peaminister Anders Fogh Rasmussen vastab küsimustele, mis puudutavad Balti riikide koalitsiooni Põhjala riikidega EL-i otsuste langetamisel, Taani-Eesti ühishuve, EL-i liitumiskõneluste lõppu 2002. aasta detsembris, EL põhiseadusliku lepingu mustandit, EL-i ülemkogu esimehe võimupiire, võimalike koalitsioonide teket EL-is, suhtumist viisavabadusse Venemaaga, rahvahääletust Eestis ja Rootsis

  18. Anders Fogh Rasmussen : Riigi suurus sõltub poliitikutest / Anders Fogh Rasmussen ; interv. Marianne Mikko

    Index Scriptorium Estoniae

    Rasmussen, Anders Fogh

    2003-01-01

    Taani peaminister Anders Fogh Rasmussen vastab küsimustele, mis puudutavad Balti riikide koalitsiooni Põhjala riikidega EL-i otsuste langetamisel, Taani-Eesti ühishuve, EL-i liitumiskõneluste lõppu 2002. aasta detsembris, EL põhiseadusliku lepingu mustandit, EL-i ülemkogu esimehe võimupiire, võimalike koalitsioonide teket EL-is, suhtumist viisavabadusse Venemaaga, rahvahääletust Eestis ja Rootsis

  19. A Psychometric Examination of Rasmussen's Ego Identity Scale.

    Science.gov (United States)

    Enright, Robert D.; And Others

    1983-01-01

    Examines Rasmussen's Ego Identity Scale for internal consistency reliability and construct validity. Subjects included 114 primarily White and middle-class seventh- and twelfth-grade students. Implications for identity assessment are drawn. (Author/RH)

  20. Rasmussen keeldus kinnitamast NATO-kõlakaid / Hendrik Vosman

    Index Scriptorium Estoniae

    Vosman, Hendrik

    2009-01-01

    Tallinna külastas Taani peaminister Anders Fogh Rasmussen, kes kohtus peaminister Andrus Ansipi ja president Toomas Hendrik Ilvesega. Eesti riigipea andis A. F. Rasmussenile üle Maarjamaa Risti I klassi teenetemärgi

  1. Rasmussen's脑炎的研究进展

    Institute of Scientific and Technical Information of China (English)

    卫华; 王玉平

    2010-01-01

    @@ Rasmussen's脑炎(Rasmussen's encephalitis,RE)是一种儿童期起病、累及一侧大脑的慢性炎症性疾病,表现为难治性局灶性癫癎、部分性癫癎持续状态(epilepsia partialis continua,EPC)、进行性神经功能缺损(偏瘫、偏盲、智力下降等).

  2. Rasmussen's legacy and the long arm of rational choice.

    Science.gov (United States)

    Dekker, Sidney W A

    2017-03-01

    Rational choice theory says that operators and others make decisions by systematically and consciously weighing all possible outcomes along all relevant criteria. This paper first traces the long historical arm of rational choice thinking in the West to Judeo-Christian thinking, Calvin and Weber. It then presents a case study that illustrates the consequences of the ethic of rational choice and individual responsibility. It subsequently examines and contextualizes Rasmussen's legacy of pushing back against the long historical arm of rational choice, showing that bad outcomes are not the result of human immoral choice, but the product of normal interactions between people and systems. If we don't understand why people did what they did, Rasmussen suggested, it is not because people behaved inexplicably, but because we took the wrong perspective. Copyright © 2016 Elsevier Ltd. All rights reserved.

  3. Recurring themes in the legacy of Jens Rasmussen

    DEFF Research Database (Denmark)

    Waterson, Patrick; Le Coze, Jean-Christophe; Andersen, Henning Boje

    2016-01-01

    The work of Jens Rasmussen over the course of the last half century represents some of the most influential contributions to the fields of cognitive science, human factors, ergonomics and safety science. His work has inspired researchers and practitioners in a number of fields including psychology......,and South Korea Ferry Disaster e Jun et al. and Lee et al., this issue), as well as recent developments in the fields of normal accident theory (Perrow, 1984), resilience engineering (Hollnagel et al., 2006)and the high reliability organisation (Weick and Sutcliffe, 2007;Le Coze, 2016a)....

  4. Reflecting on Jens Rasmussen's legacy (2) behind and beyond, a 'constructivist turn'.

    Science.gov (United States)

    Le Coze, Jean-Christophe

    2017-03-01

    This article is the second part of a study on the legacy of Jens Rasmussen. The first article, subtitled 'A Strong Program for a Hard Problem', looks back on his 30 years of scientific contribution, from 1969 to 2000. This second article explores and investigates some of the intellectual roots which influenced his thinking, using them as a basis to understand some limits and move forward. Indeed, historically oriented studies such as this one are not only tributes to researchers, but a way to differentiate and contrast our present situation with the past in order to integrate contemporary trends, be they theoretical or empirical, or oriented towards research and new models. In the first section of this article, I offer a synthesis of the background covered in the previous article, but I use a tree here as a graphical complement. Branches of the tree show the many fruitful directions opened by Jens Rasmussen, directions which inspired many researchers. In the second part, I address what I believe to be behind this wealth of engineering legacy: cybernetics. I contend that cybernetics has had a profound influence on his thinking and provided him key principles for his inspiring and successful models. To develop the tree image, one might say that cybernetics is the trunk of the tree. Finally, in the third part, I take the opportunity to explore the relevance of extending and sensitising his program to constructivist discourses. After an introduction to this discourse, identifying four types of constructivisms (cognitive, social, epistemological and anthropological), I characterise this move as a 'constructivist turn'. Copyright © 2015 Elsevier Ltd. All rights reserved.

  5. Antihyperlipidemic Activities of Common Garden Peony ( Paeonia lactifl ora Pall.

    Directory of Open Access Journals (Sweden)

    Tserenlkham Tserendejid

    2013-12-01

    Full Text Available We studied different extracts of aboveground and underground parts of Paeonia lactifl ora Pall.in experiment. For doing so this research needs to start up with total cholesterol. Total cholesterol is a direct cholesterol measurement that measures all cholesterol molecules in the blood, including low density lipoproteins (LDL, high density lipoproteins (HDL, and very low density lipoproteins (VLDL. The serum total cholesterol (TC and low density lipoproteins (LDL levels were signifi cantly different in the experimentally-induced hypercholesterolemia rats. Effect on serum triglyceride (TG level compared to control group, simvastatin and hypercholesterolemia diet (HD, but almost all were similar with simvastatin. Effect on serum high density lipoproteins (HDL level compared between those. Extracts (PL1, PL2 were lower, almost the same with hypercholesterolemia diet (HD.

  6. Päike ja pall : [luuletused] / Ott Arder

    Index Scriptorium Estoniae

    Arder, Ott

    2001-01-01

    Sisu: Päike ja pall ; Õuna ja lõuna ; Kõige ilusam asi ; Emajõgi ; Väikemehe probleem ; Küünal ; Kapten ; Kaksteist kilu ja kaks teist kilu ; Suur ja seisev, ripub seinal ; Laul tagumisest vagunist ; Ultimaatum ; Ilus algus ; Pliiat(siga) ; Mure ja Amour ; kodust ja loomadest ; Eesli jõulupuu ; Aja saapad ; Lendav järv ; Unenäolaul ; Tere hommikust ja õhtust ; Kõik, mis juhtub ja ei juhtu ; Kas panna päkka või visata varvast ; Lihtne mees ; Väljaütlev ; Külm sõda ; Ohkav kruvi ; Metsa all ; Lauluke ; Unemetsades ; Suur rõõm ja väike mure ; Hea muusika ; Koer poiss ja plika ; Kes mängida veel ei oska ; Raske lumi ; Mere kaldal ; Unenäoukse taga

  7. Glacial Refugium of Pinus pumila (Pall.) Regel in Northeastern Siberia

    Energy Technology Data Exchange (ETDEWEB)

    Shilo, N A; Lozhkin, A V; Anderson, P M; Brown, T A; Pakhomov, A Y; Solomatkina, T B

    2007-02-10

    One of the most glowing representatives of the Kolyma flora [1], ''Pinus pumila'' (Pall.) Regel (Japanese stone pine), is a typical shrub in larch forests of the northern Okhotsk region, basins of the Kolyma and Indigirka rivers, and high-shrub tundra of the Chukchi Peninsula. It also forms a pine belt in mountains above the forest boundary, which gives way to the grass-underbrush mountain tundra and bald mountains. In the southern Chukchi Peninsula, ''Pinus pumila'' along with ''Duschekia fruticosa'' (Rupr.) Pouzar and ''Betula middendorffii'' Trautv. et C. A. Mey form trailing forests transitional between tundra and taiga [2]. Pinus pumila pollen, usually predominating in subfossil spore-and-pollen spectra of northeastern Siberia, is found as single grains or a subordinate component (up 2-3%, rarely 10%) in spectra of lacustrine deposits formed during the last glacial stage (isotope stage 2) in the Preboreal and Boreal times of the Holocene. Sometimes, its content increases to 15-22% in spectra of lacustrine deposits synchronous to the last glacial stage near the northern coast of the Sea of Okhotsk [3], evidently indicating the proximity of Japanese stone pine thickets.

  8. "Naturfolk" i teori og praksis: skildringen av samene og den nordlige naturen i Knud Rasmussens Lapland

    Directory of Open Access Journals (Sweden)

    Fredrik Christian Brøgger

    2014-07-01

    Full Text Available This article focuses on the portrayal of reindeer Sami in the Danish explorer Knud Rasmussen's early book Lapland from 1907, a work that has received relatively little attention in Rasmussen scholarship. His characterizations of the Sami reflect conventional, paternalistic ideas of race and culture at the turn of the century as well as romantic-sentimental conceptions of indigenous peoples as noble savages. Rasmussen is a lively storyteller, however, and the immediacy and vividness of his depictions simultaneously open up for perspectives that, at least partly, serve to undermine traditional stereotypes. If read closely, Rasmussen's narrative evinces clear tensions between its conventional generalizations about the reindeer Sami as an indigenous people and the direct, phenomenological descriptions that are the products of Rasmussen's actual encounter with them. At the same time his instinctive sympathy for the Sami is enlarged by his own, deeply personal yearning for a life style and culture grounded in Northern cold and winter, which he encountered growing up in Greenland and which runs like a leitmotif through all his writing.

  9. MRI findings in the diagnosis and monitoring of rasmussen's encephalitis Achados de RM no diagnóstico e monitorização da encefalite de Rasmussen

    Directory of Open Access Journals (Sweden)

    Andréia V. Faria

    2009-09-01

    Full Text Available Rasmussen's encephalitis is a devastating syndrome of multifocal brain dysfunction and focal seizures. Magnetic resonance (MR findings, associated with clinical data and electroencephalogram (EEG, may indicate the diagnosis and could be an indicative of prognosis. We studied 5 patients with Rasmussen's encephalitis, assessing clinical history and MR images. All patients had refractory focal seizures with a predominant motor component associated with hemispheric atrophy, that was proportional to severity of disease and neurological deficits in these patients. Gray and white matter abnormal signal on T2 MR images were found in patients who had hemiparesis. It was not related to the duration of the disease but to aggressiveness. MR proton spectroscopy in severe disease showed lactate and choline increase and decreased NAA, reflecting neuronal and axonal loss, gliosis and elevated membrane turnover and recent - crisis (not controlled. MR studies, in addition to help in diagnosis, may be useful for monitoring metabolic changes and progression of disease in Rasmussen's encephalitis.A encefalite de Rasmussen é uma devastadora síndrome com disfunção cerebral multifocal e convulsões focais. Achados de ressonância magnética (RM, associados aos dados clínicos e de eletrencefalograma (EEG, podem indicar o diagnóstico e podem ser indicativos de prognóstico. Foram estudados 5 pacientes com encefalite de Rasmussen, avaliando a história clínica e imagens de RM. Todos os pacientes apresentavam crises epilépticas focais refratárias com componente predominantemente motor associadas à atrofia hemisférica, que foi proporcional à gravidade da doença e déficits neurológicos nestes pacientes. Alteração da intensidade de sinal nas substâncias branca e cinzenta, nas sequências ponderadas em T2, foram encontradas nos pacientes com hemiparesia. Ela não estava relacionada com a duração da doença, mas à severidade. A espectroscopia de pr

  10. Den gode intentionens kunst: Kritik og kompleksitet i kunstformidlingens tidsalder i lys af Lilibeth Cuenca Rasmussens Afghan Hound

    DEFF Research Database (Denmark)

    Danbolt, Mathias

    2016-01-01

    I den kritikerroste performancen Afghan Hound (2011) ønsker Lilibeth Cuenca Rasmussen å fungere som “et talerør for dem som ikke har en stemme i sine respektive samfunn – folk som er undertrykt” (Cuenca Rasmussen 2011: np). Kunstnerens gode intensjon om å gi stemme til de stemmeløse har blitt...

  11. Provável síndrome de Rasmussen: relato de caso

    Directory of Open Access Journals (Sweden)

    CORAL LUÍZ CARLOS

    1999-01-01

    Full Text Available A síndrome de encefalite crônica com epilepsia (síndrome de Rasmussen ocorre tipicamente em crianças e é caracterizada pelo desenvolvimento de epilepsia focal intratável, hemiparesia progressiva e deterioração intelectual. A etiologia é desconhecida e as anormalidades patológicas variam com a fase da doença. Relatamos o caso de um paciente jovem, com 17 anos de idade, com apresentação clínica da provável síndrome de Rasmussen. Discutimos a etiologia e o tratamento da patologia.

  12. Functional hemispherotomy in Rasmussen syndrome in the absence of classic MRI findings

    Directory of Open Access Journals (Sweden)

    Yasunori Nagahama

    2017-01-01

    Full Text Available A 7-year-old previously healthy girl presented with a left-sided focal seizure without impaired consciousness and subsequently developed epilepsia partialis continua. Initial MRI was normal, and the subsequent images only showed a focal T2/FLAIR hyperintense area without cortical atrophy. She was diagnosed with Rasmussen syndrome by pathology and promptly treated with functional hemispherotomy. Rasmussen syndrome is a rare progressive neurological disorder, the only definitive cure for which is hemispheric disconnection. The disease presents a management dilemma, especially early in disease course without characteristic neuroimaging features. A high index of suspicion, multidisciplinary approach, and clear timely communication with the family are critical.

  13. Serial MRI and MRS studies with unusual findings in Rasmussen's encephalitis

    Energy Technology Data Exchange (ETDEWEB)

    Tuerkdogan-Soezueer, D. [Department of Pediatric Neurology, Institute of Neurological Sciences, Marmara University, Istanbul (Turkey); Oezek, M.M.; Pamir, M.N. [Department of Neurosurgery, Institute of Neurological Sciences, Marmara University, Istanbul (Turkey); Sav, A. [Department of Pathology, Institute of Neurological Sciences, Marmara University, Istanbul (Turkey); Dincer, A. [Radyomar MR Center, Istanbul (Turkey)

    2000-06-01

    Rasmussen's syndrome is characterized by intractable seizures and progressive neuropsychiatric deterioration secondary to unilateral cortical inflammation and tissue destruction. Diagnosis of Rasmussen's syndrome in the early phase depends mainly on the clinical features. Neuroimaging and histopathologic examinations may not be specific during this period. We report a case of Rasmussen's syndrome followed by serial MRI and magnetic resonance spectroscopy (MRS) studies over a 3- to 16-month period. A healthy 6-year-old boy presented with focal motor seizures. An MRI study demonstrated prominent enlargement and T2 hyperintensity of the left mesial temporal lobe and perisylvian region. This early finding evolved to volume loss and later progressive atrophy of the ipsilateral hemisphere when epilepsia partialis continua occurred. Being aware of those early MRI features in a patient with increasing frequency of focal motor seizures should suggest Rasmussen's syndrome. In addition, we found prominently increased myoinositol concentration in atrophic cortex which might reflect increased gliosis in the late period of the disease. (orig.)

  14. Transcranial direct current stimulation improves seizure control in patients with Rasmussen encephalitis.

    Science.gov (United States)

    Tekturk, Pinar; Erdogan, Ezgi Tuna; Kurt, Adnan; Kocagoncu, Ece; Kucuk, Zeynep; Kinay, Demet; Yapici, Zuhal; Aksu, Serkan; Baykan, Betul; Karamursel, Sacit

    2016-03-01

    Rasmussen encephalitis is associated with severe seizures that are unresponsive to antiepileptic drugs, as well as immunosuppressants. Transcranial direct current stimulation (t-DCS) is a non-invasive and safe method tried mostly for focal epilepsies with different aetiologies. To date, there is only one published study with two case reports describing the effect of t-DCS in Rasmussen encephalitis. Our aim was to investigate the effect of t-DCS on seizures in Rasmussen encephalitis and to clarify its safety. Five patients (mean age: 19; three females), diagnosed with Rasmussen encephalitis were included in this study. Patients received first cathodal, then anodal (2 mA for 30 minutes on three consecutive days for non-sham stimulations), and finally sham stimulation with two-month intervals, respectively. Three patients received classic (DC) cathodal t-DCS whereas two patients received cathodal stimulation with amplitude modulation at 12 Hz. Afterwards, all patients received anodal stimulation with amplitude modulation at 12 Hz. In the last part of the trial, sham stimulation (a 60-second stimulation with gradually decreasing amplitude to zero in the last 15 seconds) was applied to three patients. Maximum current density was 571 mA/m2 using 70 mm x 50 mm wet sponge electrodes with 2-mA maximum, current controlled stimulator, and maximum charge density was 1028 C/m2 for a 30-minute stimulation period. After cathodal stimulation, all but one patient had a greater than 50% decrease in seizure frequency. Two patients who received modulated cathodal t-DCS had better results. The longest positive effect lasted for one month. A second trial with modulated anodal stimulation and a third with sham stimulation were not effective. No adverse effect was reported with all types of stimulations. Both classic and modulated cathodal t-DCS may be suitable alternative methods for improving seizure outcome in Rasmussen encephalitis patients.

  15. Vanemahüvitis : korduma kippuvad küsimused / Katre Pall

    Index Scriptorium Estoniae

    Pall, Katre, 1970-

    2007-01-01

    Sotsiaalministeeriumi spetsialist Katre Pall vastab lugejate küsimustele: vanemahüvitis ja teised peretoetused, muud tulud ja vanemahüvitis, ilma sünnituspuhkuseta, kui sünnitan Soomes. Lisatud: vanemahüvitise ABC

  16. Anti-inflammatory and immunomodulatory effects of Paeonia lactiflora Pall., a traditional Chinese herbal medicine

    Directory of Open Access Journals (Sweden)

    Dong-Yi eHe

    2011-02-01

    Full Text Available In China, Korea and Japan, a decoction of the dried root without bark of Paeonia lactiflora Pall. has been used in the treatment of rheumatoid arthritis, systemic lupus erythematosus, hepatitis, dysmenorrhea, muscle cramping and spasms, and fever for more than 1200 years. A water/ethanol extract of the root is now known as total glucosides of paeony (TGP, which contains more than 15 components. Paeoniflorin is the most abundant ingredient and accounts for the pharmacological effects observed with TGP in both in vitro and in vivo studies. The analgesic effect of TGP was confirmed in various animal models of pain, which may be mediated partly by adenosine A1 receptor. The direct anti-inflammatory effects of TGP were observed in animal models of both acute and subacute inflammation, by inhibiting the production of prostaglandin E2, leukotrience B4, and nitric oxide, and by suppressing the increase of intracellular calcium ion concentration. TGP was also reported to have protective effects of cells against oxidative stress. In vitro, dual effects of TGP were noted on the proliferation of lymphocytes, differentiation of Th/Ts lymphocytes, and the production of pro-inflammatory cytokines and antibodies. In vivo, TGP inhibited the delayed-type hypersensitivity in immuno-activated mice, and enhanced the delayed-type hypersensitivity in immuno-suppressed mice. In adjuvant arthritis rats, paeoniflorin exerted immunosuppressive effects. The beneficial effects of TGP in treating rheumatoid arthritis were verified by randomized controlled trials. The adverse events of TGP were mainly gastrointestinal tract disturbances, mostly mild diarrhea.

  17. Rasmussen aneurysm - a case report in a child and review of the literature; Aneurisma de Rasmussen - relato de um caso em crianca e revisao da literatura

    Energy Technology Data Exchange (ETDEWEB)

    Matos, Adriana Silva; Goyanna, Fabiola; Gomes, Leo; Alexandre, Alexandre Kalil Castanheira; Rocha, Josilton Antonio; Souza, Paulo Engracio Matos de; Machado, Marcos; Santos, Marcelo Benicio dos [Hospital Sao Rafael, Salvador, BA (Brazil). Servico de Bioimagem

    2000-04-01

    The authors report a case of an 11-year-old boy with a Rasmussen aneurysm presenting with dyspnea, fever and hemoptysis. The patient underwent radiological, tomographic and angiographic assessments. The pathogenesis of the aneurysm was related to the erosion of a pulmonary artery branch with replacement of the adventitia and media layers by granulation tissue, due to an adjacent tuberculous cavity. A plain chest x-ray showed bilateral nodular opacities, largest on the right lung, which enhanced simultaneously with the mediastinal vessels on CT. Its vascular nature was confirmed by angiographic studies.(author)

  18. Rasmussen's encephalitis: the relevance of neuropsychological assessment in patient's treatment and follow up

    Directory of Open Access Journals (Sweden)

    Guimarães Catarina Abraão

    2002-01-01

    Full Text Available Rasmussen's encephalitis is characterized by refractory epilepsy, neurological deterioration and progressive atrophy of one cerebral hemisphere. The objective of this study is to describe the importance of neuropsychological evaluation in the treatment decision and follow-up of patients with Rasmussen´s encephalitis. Neuropsychological assessment was performed in two steps. Firstly, the clinical history was obtained and the Vineland adaptative behavior scale (VABS was applied. After this first step, the patients with social maturity level equal or higher than the inferior limit underwent a battery of neuropsychological assessment. We evaluated three patients before any specific treatment was started, and six months after the intervention (surgery or plasmapheresis. Patient 1 underwent left hemispherectomy and had global improvement on second neuropsychological assessment. This suggests that the decision of performing surgery was adequate. Patients 2 and 3 underwent plasmapheresis. They did not present cognitive decline between both evaluations which suggest that our decision of postponing surgery was adequate as well. We conclude that neuropsychological assessment is important when evaluating patients with Rasmussen´s encephalitis. That is especially true for patients in whom disease progression is slow, and surgery timing has to be carefully planned.

  19. The 3D Lagrangian Integral Method. Henrik Koblitz Rasmussen

    DEFF Research Database (Denmark)

    Rasmussen, Henrik Koblitz

    2003-01-01

    with a second order Runge-Kutta integration method. In any development of a numerical method for viscoelastic flow it is important to focus on the constitutive equation associated to the method. For instance the K-BKZ model is not adequate to describe both shear and extensional flow using the same constitutive...

  20. What is the fate of disconnected brain tissue in a child with Rasmussen syndrome? A case report

    Energy Technology Data Exchange (ETDEWEB)

    Kim, S.J.; Park, Y.D. [Dept. of Neurology (Child), Medical Coll. of Georgia, Augusta, GA (United States); Pillai, J. [Dept. of Radiology, Medical Coll. of Georgia, Augusta, GA (United States)

    2003-04-01

    We describe a case of Rasmussen syndrome in a 7-year-old boy, presenting with epilepsia partialis continua, hemiplegia, and progressive mental deterioration. The initial MRI examination was normal, followed by progressive left hemispheric cortical atrophy and abnormal high signal intensity over the left occipital, parietal, and cingulate gyral areas over an 18-month period. On the basis of the clinical diagnosis and biopsy findings of Rasmussen syndrome, functional hemispherectomy was carried out at 7.5 years of age with alleviation of clinical seizures for the following 44 months. The follow-up MRI demonstrated atrophic changes involving the remaining left hemisphere with increased signal and cortical volume loss, as well as the absence of abnormal signal in the right hemisphere at 10 years of age. Our MRI findings are consistent with the progression of Rasmussen syndrome in the ipsilateral hemisphere even after functional-hemispherectomy without clinical seizures. (orig.)

  1. Supporting the human life-raft in confronting the juggernaut of technology: Jens Rasmussen, 1961-1986.

    Science.gov (United States)

    Kant, Vivek

    2017-03-01

    Jens Rasmussen's contribution to the field of human factors and ergonomics has had a lasting impact. Six prominent interrelated themes can be extracted from his research between 1961 and 1986. These themes form the basis of an engineering epistemology which is best manifested by his abstraction hierarchy. Further, Rasmussen reformulated technical reliability using systems language to enable a proper human-machine fit. To understand the concept of human-machine fit, he included the operator as a central component in the system to enhance system safety. This change resulted in the application of a qualitative and categorical approach for human-machine interaction design. Finally, Rasmussen's insistence on a working philosophy of systems design as being a joint responsibility of operators and designers provided the basis for averting errors and ensuring safe and correct system functioning. Copyright © 2016 Elsevier Ltd. All rights reserved.

  2. Possible universal quantum algorithms for generalized Khovanov homology and the Rasmussen's invariant

    Science.gov (United States)

    Vélez, Mario; Ospina, Juan

    2012-06-01

    Possible quantum algorithms for generalized Khovanov homology and the Rasmussen's invariant are proposed. Such algorithms are resulting from adaptations of the recently proposed Kauffman's algorithm for the standard Khovanov homology. The method that was applied consists in to write the relevant quantum invariant as the trace of a certain unitary operator and then to compute the trace using the Hadamard test. We apply such method to the quantum computation of the Jones polynomial, HOMFLY polynomial, Chromatic polynomial, Tutte polynomial and Bollobàs- Riordan polynomial. These polynomials are quantum topological invariants for knots, links, graphs and ribbon graphs respectively. The Jones polynomial is categorified by the standard Khovanov homology and the others polynomials are categorified by generalized Khovanov homologies, such as the Khovanov-Rozansky homology and the graph homologies. The algorithm for the Rasmussen's invariant is obtained using the gauge theory; and the recently introduced program of homotopyfication is linked with the super-symmetric quantum mechanics. It is claimed that a new program of analytification could be development from the homotopyfication using the celebrated Atiyah-Singer theorem and its super-symmetric interpretations. It is hoped that the super-symmetric quantum mechanics provides the hardware for the implementation of the proposed quantum algorithms.

  3. Rasmussen's Encephalitis

    Science.gov (United States)

    ... speech, paralysis on one side of the body (hemiparesis), inflammation of the brain (encephalitis), and mental deterioration. ... speech, paralysis on one side of the body (hemiparesis), inflammation of the brain (encephalitis), and mental deterioration. ...

  4. Rasmussen's encephalitis

    African Journals Online (AJOL)

    2011-03-08

    Mar 8, 2011 ... Supporting this theory was presence of antibodies said to bind to type-3 glutamate ... (receptive or expressive); and cognitive deficits (memory intellectual .... count 175,000 – 504,000 109/L. His blood film picture showed ...

  5. 76 FR 11259 - Notice of Intent To Prepare an Environmental Impact Statement for the Proposed Rasmussen Valley...

    Science.gov (United States)

    2011-03-01

    ... your personal identifying information--may be made publicly available at any time. While you can ask us... Department of Lands. Mining is proposed to begin at the southern end of the Rasmussen Valley Mine deposit...; recreation; and socio-economics such as employment and the continued operation of a fertilizer plant...

  6. Ecological interface design and system safety: One facet of Rasmussen's legacy.

    Science.gov (United States)

    Bennett, Kevin B

    2017-03-01

    The focus of this manuscript is on cognitive systems engineering/ecological interface design (CSE/EID) and the role that this framework may play in improving system safety. First, the decision making and problem solving literatures are reviewed with an eye towards informational needs that are required to support these activities. The utility of two of Rasmussen's analytical tools (i.e., the abstraction and aggregation hierarchies) in conducting work domain analyses to identify associated information (i.e., categories and relationships) is discussed. The importance of designing ecological displays and interfaces that span the informational categories in the abstraction hierarchy is described and concrete examples are provided. The potential role that ecological interfaces can play in providing effective decision making (i.e., preventing accidents) and problem solving (i.e., dealing with accidents) support, thereby improving the safety of our socio-technical systems, is explored. Copyright © 2015 Elsevier Ltd. All rights reserved.

  7. 白芍的化学成分研究%A study on the chemical constituents of Paeonia lactiflora Pall

    Institute of Scientific and Technical Information of China (English)

    张晓燕; 王金辉; 李铣

    2001-01-01

    Five compounds were isolated from Paeonia lactiflora Pall.. Theywere identified as paeoniflorin(1),benzoylpaeoniflorin(2),galloylpaeoniflorin(3),1,2,3,4,6-galloyl glucose(4) and daucosterol(5).%从白芍(PaeonialactifloraPall.)的干燥根中分离得到5个化合物,经理化常数和光谱分析分别鉴定为芍药苷(1)、苯甲酰芍药苷(2)、没食子酰芍药苷(3)、1,2,3,4,6-五没食子酰基葡萄糖(4)和胡萝卜苷(5)。

  8. 盐地碱蓬的染色体核型分析%Karyotype analysis of Suaeda salsa (L.) Pall

    Institute of Scientific and Technical Information of China (English)

    张峰; 姚燕

    2013-01-01

    The paper originally analyzes the number of chromosomes and karyotype of Suaeda salsa (L. ) Pall. Results show that its chromosome number is 2n =18, and that its karyotype formula is K(2n) =2x = 18 = 16m +2sm. The karyotype is 1A based on the classification standard of Stebbins.%本文首次对盐地碱蓬(Suaeda salsa(L.)Pall.)的染色体数目和核型进行了分析研究.结果表明,盐地碱蓬的染色体数目2n=18,核型公式为K(2n)=18=16m +2sm.根据Stebbins的核型分类标准,盐地碱蓬的核型属1A型.

  9. Cultivars of Medicinal Paeonia Lactiflora Pall.in China%中国药用芍药栽培品种

    Institute of Scientific and Technical Information of China (English)

    查良平; 王德群; 彭华胜; 杨俊

    2011-01-01

    Objective To investigate into the cultivars of medicinal Paeonia lactiflora Pall. from four genuine producing areas in China. Methods Four genuine producing areas of medicinal paeonia lactiflora Pall. in China were investigated, such as Bozhou in Anhui province, Heze in Shandong province, Zhongjiang in Sichuan province, and Pan’an in Zhejiang province. Germplasm of Paeonia Radix Alba in these areas were researched. Results There were six cultivars of Paeoniae lactiflora Pall. in China, namely, P. lactiflora ‘ Bozhoushaoyao ’ , P. lactiflora ‘ Hezeshaoyao ’ , P. lacti.flora ‘ Baihuachuanshaoyao ’ , P. lactiflora ‘ Honghuachuanshaoyao’ , P. lactiflora ‘ Baihuahangshaoyao ’ , and P. lactiflora ‘Honghuahangshaoyao’. The taxa key of the six cultivars was reported. Conslusion As Didao herbs, "Baishao" were derived from different cultivars of P. lactiflora Pall. .%目的 调查四大地道产区药用芍药的栽培品种.方法 对安徽亳州、山东菏泽、四川中江和浙江磐安的药用芍药进行标本研究.结果 目前我国药用芍药有6个栽培品种,分别为亳州芍药Paeonia lactiflora ‘Bozhoushaoyao'、菏泽芍药Paeonia lactiflora ‘Hezeshaoyao'、白花川芍药Paeonia lactiflora ‘Baihuachuanshaoyao'、红花川芍药Paeonia lactiflora ‘Honghuachuanshaoyao'、白花杭芍药Paeonia lactiflora ‘Baihuahangshaoyao'和红花杭芍药Paeonia lactiflora ‘Honghuahangshaoyao'.列出了6个栽培品种的分类检索表.结论 地道药材白芍来源于不同的栽培品种.

  10. Voltage-gated potassium channels autoantibodies in a child with rasmussen encephalitis.

    Science.gov (United States)

    Spitz, Marie-Aude; Dubois-Teklali, Fanny; Vercueil, Laurent; Sabourdy, Cécile; Nugues, Frédérique; Vincent, Angela; Oliver, Viviana; Bulteau, Christine

    2014-10-01

    Rasmussen encephalitis (RE) is a severe epileptic and inflammatory encephalopathy of unknown etiology, responsible for focal neurological signs and cognitive decline. The current leading hypothesis suggests a sequence of immune reactions induced by an indeterminate factor. This sequence is thought to be responsible for the production of autoantibody-mediated central nervous system degeneration. However, these autoantibodies are not specific to the disease and not all patients present with them. We report the case of a 4-year-old girl suffering from RE displaying some atypical features such as fast evolution and seizures of left parietal onset refractory to several antiepileptics, intravenous immunoglobulins, and corticosteroids. Serum autoantibodies directed against voltage-gated potassium channels (VGKC) were evidenced at 739 pM, a finding never previously reported in children. This screening was performed because of an increased signal in the temporolimbic areas on brain magnetic resonance imaging, which was similar to what is observed during limbic encephalitis. The patient experienced epilepsia partialis continua with progressive right hemiplegia and aphasia. She underwent left hemispherotomy at the age of 5.5 years after which she became seizure free with great cognitive improvement. First described in adults, VGKC autoantibodies have been recently described in children with various neurological manifestations. The implication of VGKC autoantibodies in RE is a new observation and opens up new physiopathological and therapeutic avenues of investigation.

  11. Isolation and Simultaneous Quantification of Nine Triterpenoids from Rosa davurica Pall.

    Science.gov (United States)

    Huo, Yayu; Gao, Yang; Mi, Jie; Wang, Xinrui; Jiang, Huimin; Zhang, Hailong

    2017-02-01

    Rosa davurica Pall. has been used as a traditional Oroqen medicine to treat dyspepsia, gastroenterologia, menoxenia and other diseases. In this study, the chemical constituents research on the fruit pulp of R. davurica led to the isolation and identification of nine bioactive pentacyclic triterpenoids and five of them were isolated from the plant for the first time. Subsequently a simple and rapid high-performance liquid chromatography (HPLC) method was established for the simultaneous quantification of the nine triterpenoids. The separation was performed on a Merges reverse phase (RP) C18 (250 × 4.6 mm, 5 μm) column through 40 min gradient delivery of 0.05% phosphoric acid aqueous solution and acetonitrile at a flow rate of 1.2 mL/min at 30°C and the detection wavelength selected was 210 nm. All of the calibration curves showed good linearity (R(2) > 0.9990) in the tested ranges. The limit of detection and the limit of quantitation were in the range of 0.21-1.27 μg/mL and 0.63-3.80 μg/mL, respectively. The established method also showed good precision, repeatability and recovery and can be used to the routine quality control of R. davurica and other herbs containing pentacyclic triterpenoids.

  12. Relationship between Major Mineral Nutrient Elements Contents and Flower Colors of Herbaceous Peony (Paeonia Lactiflora Pall.

    Directory of Open Access Journals (Sweden)

    Chengzhong Li

    2015-02-01

    Full Text Available Herbaceous peony (Paeonia lactiflora Pall. is a famous ornamental plant with bright flowers and lush leaves. The flower petal can be used as a fragrant food additive. Understanding the mineral nutrient contents in P. lactiflora is necessary for guiding its cultivation practices as well as its use as a food additive. In this study, we investigated the mineral contents including Calcium (Ca, Potassium (K, Magnesium (Mg, Copper (Cu, iron (Fe and Zinc (Zn in petals and leaves of 20 selected herbaceous peony cultivars in four groups according to their flower colors and the relationship between major mineral nutrient elements contents and flower colors was assessed. In petals, the contents of minerals were in this order K>Ca>Mg>Fe>Zn>Cu; while in leaves were: Ca>K>Mg>Fe>Zn>Cu. Major element contents in petals and leaves among 4 cultivar groups were different at statistically significant levels. Petals in red or purple have higher amount of most major minerals than those in white or pink colors. The wide range of mineral element contents among cultivars is attributed to genotypic variations. The correlations of major mineral elements in the petals and leaves of herbaceous peony cultivars indicate that mineral ions compete for the same absorption sites. The results provided some scientific support for petal nutrition of herbaceous peony and selecting herbaceous peony flowers with dark colors for edible is feasible.

  13. 赤芍中的单萜类成分%Monoterpenes of Paeonia lactiflora Pall

    Institute of Scientific and Technical Information of China (English)

    王彦志; 冯卫生; 石任兵; 刘斌; 姜艳艳

    2008-01-01

    目的研究毛茛科植物赤药(Paeonia lactiflora Pall.)的化学成分.方法应用色谱技术分离纯化,波谱方法解析结构.结果从赤芍中分离出5个化合物:9-乙基芍药新苷A(1),(1S,2S,4R)-反式-1,8-桉叶素-2-O-(6-O-α-L-鼠李糖基)-β-D-葡萄糖苷(2),(1S,2S,4R)-反式-2-羟基-1,8-桉叶素(3),没食子酸(4),没食子酸乙酯(5).结论化合物1为新的天然产物,2、3为首次从赤芍中分离得到.

  14. Reproduction, aging and mortality rate in social subterranean mole voles (Ellobius talpinus Pall.).

    Science.gov (United States)

    Novikov, E; Kondratyuk, E; Petrovski, D; Titova, T; Zadubrovskaya, I; Zadubrovskiy, P; Moshkin, M

    2015-12-01

    Eusocial subterranean rodents of the Bathyergidae family have enormous longevity. The long lifespan of these species is associated with negligible senescence, that is, an absence of the signs of age-related deterioration in physical condition. The question arises as to whether these features are unique to eusocial Bathyergids or typical of other social subterranean rodents as well. In the present study, we analysed data from observations of a social subterranean Microtinae rodent, the northern mole vole (Ellobius talpinus Pall.), which, like mole-rats, has reproductive skew. Among the individuals captured in the wild and maintained in captivity, females that reproduced lived significantly longer than non-breeding females. We did not find any changes in muscle strength with age in any of the demographic groups studied. Faecal glucocorticoid concentrations before death were significantly higher in non-breeding females than in breeding females and males. Increased adrenocortical activity may be one mechanism responsible for the decreased lifespan of non-reproducing individuals of social subterranean rodents. We conclude that the patterns of aging, although different in some respects, are generally common for social subterranean rodents of different taxonomic groups.

  15. The Root Extract of Gentiana macrophylla Pall. Alleviates Cardiac Apoptosis in Lupus Prone Mice.

    Directory of Open Access Journals (Sweden)

    Chih-Yang Huang

    Full Text Available The roots of the perennial herb Gentiana macrophylla Pall. (GM are known as Qinjiao, which has been used for centuries to treat systemic lupus erythematosus (SLE. However, little is known about the effects of GM on cholesterol-aggravated cardiac abnormalities in SLE, and the mechanisms thereof. This study investigates whether GM exhibits anti-apoptotic effects, focusing on the left ventricle (LV of NZB/W F1 mice fed with high-cholesterol diet. The morphology and apoptotic status of ventricular tissues were determined by microscopy and Terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL assay. Levels of apoptotic biomarkers were determined by immunoblotting. The results thus obtained revealed that GM significantly reduced the cholesterol-aggravated apoptosis of LV in NZB/W F1 mice by suppressing both intrinsic and extrinsic apoptotic pathways. Additionally, GM significantly increased the cardiac insulin-like growth factors (IGF-1 survival signaling and anti-apoptotic proteins in LV tissues. Accordingly, GM is considered to be beneficial in alleviating cholesterol-aggravated cardiac damage in SLE, and therefore constitute an alternative treatment for SLE patients with cardiac abnormalities.

  16. Simultaneous quantification of 11 isoquinoline alkaloids in Corydalis impatiens (Pall.) Fisch by HPLC.

    Science.gov (United States)

    Niu, Xiaofeng; Li, Weifeng; Xu, Hongbo; Liu, Xia; Qi, Lin

    2013-07-01

    Isoquinoline alkaloids are the primary active ingredients of Corydalis, but an analytical method for quality assessment of the active ingredients in Corydalis impatiens (Pall). Fisch has not been reported. A new, simple, and multiple-component quantification method was developed for the simultaneous quantification of 11 isoquinoline alkaloids including capnoidine, chelianthifoline, bicuculline, protopine, isoapocavidine, apocavidine, cavidine, tetrahydroepiberberine, ochotensimine, tetrahydrocoptisine, and tetrahydrocorysamine in C. impatiens. Separation of the isoquinoline alkaloids was performed on a RP C18 column (150 × 4.6 mm, 5 μm) with potassium dihydrogen phosphate buffer (pH 2.5, adjusted by phosphoric acid)/acetonitrile (53:47, v/v) containing 0.3% sodium dodecyl sulfonate. The flow rate and detection wavelength were set at 1 mL/min and 295 nm, respectively. Full validation of the assay was carried out including linearity, precision, accuracy, stability, LOD, and limit of quantitation. All calibration curves showed a good linear relationship (r > 0.999) in test range. The results demonstrated that the developed method was reliable, rapid, and specific. Six batches of C. impatiens samples from different sources were determined using the established method. The contents of alkaloids ranged from 11.68 to 351.83 μg/g. This method can be applied for quality evaluation and control of C. impatiens. Eleven isoquinoline alkaloids were first reported on simultaneous determination with HPLC.

  17. Rhizobium helanshanense sp. nov., a bacterium that nodulates Sphaerophysa salsula (Pall.) DC. in China.

    Science.gov (United States)

    Qin, Wei; Deng, Zhen Shan; Xu, Lin; Wang, Na Na; Wei, Ge Hong

    2012-05-01

    Studying rhizobia in the root nodules of Sphaerophysa salsula (Pall.) DC in the northwest of China, we obtained five strains classified as genus Rhizobium on the basis of their 16S rRNA gene sequences. The sequence similarity of strain CCNWQTX14(T) with the most related species was 99.0%. Further phylogenetic analysis of housekeeping genes (recA and atpD) suggested the five strains comprised a novel lineage within Rhizobium. The nifH and nodD gene sequences of CCNWQTX14(T) were phylogenetically closely related with those of Sinorhizobium kummerowiae and R. sphaerophysae, respectively. The five strains isolated from different places were also distinct from related Rhizobium species using ERIC fingerprint profiles. The DNA-DNA hybridization value was 41.8% between CCNWQTX14(T) and Rhizobium sphaerophysae CCNWGS0238(T). Our novel strains were only able to form effective nodules on its original host Sphaerophysa salsula. Our data showed that the five Rhizobium strains formed a unique genomic species, for which a novel species Rhizobium helanshanense sp. nov. is proposed. The type strain is CCNWQTX14(T) (=ACCC 16237(T) =HAMBI 3083(T)).

  18. ENVIRONMENTAL TECHNOLOGY VERIFICATION REPORT PHYSICAL REMOVAL OF CRYPTOSPORIDIUM OOCYSTS AND GIARDIA CYSTS IN DRINKING WATER PALL CORPORATION WPM-1 MICROFILTRATION SYSTEM AT PITTSBURGH, PA - NSF 00/09/EPADW395

    Science.gov (United States)

    Verification testing of the Pall Corporation WPM-1 Microfiltration Pilot System was conducted from February 3 to March 5, 1999. The Pall WPM-1 membrane is a hollow fiber type microfiltration membrane made of polyvinylidenefluoride (PVDF). It has a 0.1 micrometer ( m) nominal por...

  19. Herbaceous Peony (Paeonia lactiflora Pall. as an Alternative Source of Oleanolic and Ursolic Acids

    Directory of Open Access Journals (Sweden)

    Jun Tao

    2011-01-01

    Full Text Available Oleanolic acid (OA and ursolic acid (UA have been proven to possess many biological activities, and much attention is focused on the search for plants which are rich in OA and UA. In this report, the OA and UA accumulation characteristics were investigated in 47 cultivars of Chinese herbaceous peony (Paeonia lactiflora Pall. and were followed in three cultivars over different developmental stages as measured by high performance liquid chromatography (HPLC. OA and UA levels in leaves and stems demonstrated an overall upward trend from May 1 to September 15 except for UA in the leaves of “Hong Feng”. The maximum values of OA and UA in leaves of “Yangfei Chu Yu”, “Fen Zhu Pan” and “Hong Feng” were 852.98, 575.60, 290.48 μg/g FW and 924.94, 827.36, 432.67 μg/g FW, respectively. The maximum values of OA and UA in stems of “Yangfei Chu Yu”, “Fen Zhu Pan” and “Hong Feng” were 359.28, 90.49, 43.90 μg/g FW and 326.86, 82.25, 56.63 μg/g FW, respectively. OA and UA contents in leaves of 47 different herbaceous peony cultivars ranged from 66.73–618.12 and 36.23–665.14 μg/g FW, respectively, with average values of 171.62 and 227.57 μg/g FW, respectively. The results suggested that the aboveground parts of herbaceous peony may be used as an alternative source of OA and UA for medicinal purposes in addition to its ornamental purposes.

  20. Establishment of Quality Standards of Paeonia Lactiflora Pall%关于芍药质量标准的制定

    Institute of Scientific and Technical Information of China (English)

    胡世林; 廖福龙; 周红涛; 冯学峰; 李文

    2004-01-01

    目的:芍药Paeonia lactiflora Pall.的根既作中药赤芍,又作白芍用,但主治病症有很大区别,本研究在探索这种区别科学性的基础上和确定芍药苷含量的可行标准.方法:直接从主要产区取样,用RAPD技术分析DNA多态性特征,用显微计数淀粉粒和草酸钙结晶的数量,用HPLC法测定芍药苷含量.结果:DNA和红外光谱指纹图谱可以区别野生和栽培,观赏栽培和药用栽培的芍药.赤芍中芍药苷含量不得低于3.5%;白芍中芍药苷的含量改为幅度限制,应在0.8%~3.5%之间,以区别于赤芍,证明中医临床将同一物种芍药区分为赤、白使用是科学的.结论:野生变家种并非是解决赤芍资源走向枯竭的正确途径;为完整准确地表达赤、白芍的来源,建议白芍定义为药用栽培芍药Paeonia lactiflora Pall. CV.Baishao经去皮、水煮等方法加工干燥的根,药材的拉丁名建议为Radix Paeoniae Lactiflorae Alba,因为同属其它种即使栽培也不作白芍用;赤芍定义为野生芍药Paeonia lactiflora Pall.var.1actiflora的干燥根,采用新的药材拉丁名Radix Paeoniae Lactiflorae Fera,因为赤芍并非赤色,其本质是野生来源;观赏芍药不能作白芍和赤芍,拉丁名亦应标明观赏Paeonia lactiflora Pall. CV.Ornata.

  1. Contributo de um programa de competências de leitura e escrita para um jovem com síndrome de Rasmussen

    OpenAIRE

    Soares, Rosa Maria Breda Gameiro

    2013-01-01

    Este trabalho insere-se no âmbito da temática da epilepsia, incidindo mais especificamente na síndrome de Rasmussen, desordem neurológica rara e progressiva caracterizada por ataques epilépticos frequentes e severos com perda de habilidades motoras. Sendo esta síndrome ainda pouco estudada tal constitui per si motivação para a aprofundar. Assim, partindo da constatação empírica de que a epilepsia interfere com as aquisições académicas de um jovem com síndrome de Rasmussen, pretendemos verific...

  2. Vaccination and Infection as Causative Factors in Japanese Patients With Rasmussen Syndrome: Molecular Mimicry and HLA Class I

    Directory of Open Access Journals (Sweden)

    Yukitoshi Takahashi

    2006-01-01

    Full Text Available Rasmussen syndrome is an intractable epilepsy with a putative causal relation with cellular and humoral autoimmunity. Almost half of the patients have some preceding causative factors, with infections found in 38.2%, vaccinations in 5.9% and head trauma in 8.9% of Japanese patients. In a patient with seizure onset after influenza A infections, cross-reaction of the patient's lymphocytes with GluRε2 and influenza vaccine components was demonstrated by lymphocyte stimulation test. Database analyses revealed that influenza A virus hemagglutinin and GluRε2 molecules contain peptides with the patient's HLA class I binding motif (HLA ࢤ A*0201. The relative risks of HLA class I genotypes for Rasmussen syndrome are 6.1 (A*2402, 6.4 (A*0201, 6.3 (A*2601 and 11.4 (B*4601. The relative risks of HLA class I-A and B haplotypes are infinity (A*2601+B*5401, 21.1 (A*2402+B*1501, 13.3 (A*2402+B*4801 and 5.1 (A*2402+B*5201. Some alleles and haplotypes of HLA class I may be the risk factors in Japanese patients. Cross-reactivity of cytotoxic T lymphocytes may contribute to the processes leading from infection to the involvement of CNS.

  3. Teaching Narrative Writing Using Comics: Delainey and Rasmussen, the Creators of "Betty," Share Their Composing Strategies as Rich Literacy Resources for Elementary Teachers

    Science.gov (United States)

    Nixon, Rhonda

    2012-01-01

    The author explores how comics texts and writing practices are rich literacy resources for educators. Few studies report on how teachers explore such texts and practices in their classrooms. The author examines how drawing improves students' narrative writing and presents findings from a 7-month case study of Delainey and Rasmussen's collaborative…

  4. Teaching Narrative Writing Using Comics: Delainey and Rasmussen, the Creators of "Betty," Share Their Composing Strategies as Rich Literacy Resources for Elementary Teachers

    Science.gov (United States)

    Nixon, Rhonda

    2012-01-01

    The author explores how comics texts and writing practices are rich literacy resources for educators. Few studies report on how teachers explore such texts and practices in their classrooms. The author examines how drawing improves students' narrative writing and presents findings from a 7-month case study of Delainey and Rasmussen's collaborative…

  5. Fast and Accurate Identification of Cross-Linked Peptides for the Structural Analysis of Large Protein Complexes and Elucidation of Interaction Networks. / Tahir, Salman; Bukowski-Wills, Jimi-Carlo; Rasmussen, Morten; Rappsilber, Juri

    DEFF Research Database (Denmark)

    Rasmussen, Morten

    Fast and Accurate Identification of Cross-Linked Peptides for the structural analysis of large protein complexes and to elucidate interaction networks. Salman Tahir Jimi-Carlo Bukowski-Wills; Morten Rasmussen; Juri RappsilberWellcome Trust Centre for Cell Biology, Edinburgh , United Kingdom   Novel...... to investigate protein structure and protein-protein interactions. When applied to single proteins or small purified protein complexes, this methodology works well. However certain challenges arise when applied to more complex samples. One of the main problems is the combinatorial increase in the search space...... Aspect: Our software efficiently and correctly identifies cross-links within large protein complexes, facilitating the construction of low-resolution 3D-models and interaction networks   .Introduction Chemical cross-linking of peptides coupled with mass spectrometry emerges as a powerful method...

  6. Viljandi maakonna hariduselu vajab läbimõeldud raputust / Hendrik Agur, Tiina Pall, Aavo Palo ; küsitlenud Liisi Seil

    Index Scriptorium Estoniae

    Agur, Hendrik, 1965-

    2007-01-01

    Viljandist pärit Tallinna Gustav Adolfi Gümnaasiumi direktor Hendrik Agur, Tallinna Kristiine Gümnaasiumi direktor Tiina Pall ja Viljandi Paalalinna Gümnaasiumi direktor Aavo Palo arutlevad Viljandimaa hariduselu tuleviku üle. Sisus ka : Seil, Liisi. Klubi liidab ühes majas kasvanud haridusjuhte

  7. [Preclinical study of immunocorrection action of the sum of active substances of Coluria geoides (Pall.) Ledeb. (Rosaceae)].

    Science.gov (United States)

    Dutova, S V; Karpova, M R; Myadelets, M A; Myasnaya, N V; Sherstoboev, E Yu

    2015-01-01

    A preclinical study of the immunocorrection action of the sum of active substances isolated from ethereal-oil plants Coluria geoides (Pall.) Ledeb. (Rosaceae family) with respect to experimental immunodeficiency showed that preparations relieve symptoms of immunodeficiency caused by the administration of cyclophosphan: suppressed synthesis of anti-erythrocyte antibodies (agglutinine) and proliferative processes in the spleen. Under the influence of C. geoides preparations, the absolute numbers of cariocytes and antibody forming cells in spleen significantly increased (compared to the group of animals with experimental immunodeficiency) and in some cases reached the background level. The drugs studied produced a more pronounced stimulating effect on the synthesis of specific immunoglobulins and proliferation of antibody forming cells of spleen as compared to the effect of Echinacea tincture. Preparation C-2 (extract from underground organs and grass of C. geoides obtained by percolation method with 70% ethanol) is most promising for in-depth research and the development of new effective drugs with immunocorrecting properties.

  8. Pall摩擦耗能减震器减震性能研究%The shock absorption properties of Pall frictional energy dissipation shock absorber

    Institute of Scientific and Technical Information of China (English)

    孙志松

    2009-01-01

    Against to the fast developing status of structural shock absorption technology, the applied situation of Pall frictional energy dissipa-tion shock absorber was introduced. The basic constitution and shack absorption properties of Pall frictional energy dissipation shock absorber were analyzed, the result indicated that it can dissipate large amount seismic energy and had better shock absorption effect with energy dissipa-tion supporting of Pall frictional shock absorption device as protective structure.%针对结构减震技术迅速发展的现状,介绍了Pall摩擦耗能减震器的应用情况,就Pall摩擦耗能减震器的基本构造及减震性能进行了分析,结果表明:采用安装Pall摩擦减震装置的耗能支撑来保护结构,可耗散大量地震能量,减震效果好.

  9. 刺玫果多糖含量测定方法优选%Study on the Determination Method for Polysaccharide Content in Rosa davurica Pall.

    Institute of Scientific and Technical Information of China (English)

    陈帅; 孙毓婷; 李锐; 钟方丽

    2012-01-01

    To optimize determination method of polysaccharide content in Rosa davurica Pall. [Method] Through precision experiment , stability experiment, recovery rate experiment and linear relationship to compare the application of phenol sulfuric acid colorimetry method and anthranone sulfuric acid colorimetry method in determining polysaccharide content in Rosa davurica Pall. [ Results ] Phenol sulfuric acid colorimetry method was superior than anthranone sulfuric acid colorimetry method in determination of polysaccharide content in Rosa davurica Pall. [Conclusion] The above determination method is stable and reliable.%[目的]优选刺玫果多糖的含量测定方法.[方法]通过精密度试验、稳定性试验、回收率试验和线性关系考察比较苯酚硫酸法和蒽酮硫酸法2种常用多糖含量测定方法在测定刺玫果多糖中的应用.[结果]苯酚硫酸法测定刺玫果多糖含量优于蒽酮硫酸法.[结论]该研究确定的多糖含量测定方法稳定、可靠,可用于刺玫果多糖的含量测定.

  10. Diagnostic imaging in 13 cases of Rasmussen's encephalitis. Can early MRI suggest the diagnosis?

    Energy Technology Data Exchange (ETDEWEB)

    Chiapparini, L.; Farina, L.; Ciceri, E.; Erbetta, A.; Savoiardo, M. [Dept. of Neuroradiology, Ist. Nazionale Neurologico ' ' C. Besta' ' , Milano (Italy); Granata, T.; Ragona, F.; Freri, E. [Dept. of Paediatric Neurology, Ist. Nazionale Neurologico ' ' C. Besta' ' , Milano (Italy); Fusco, L. [Dept. of Paediatric Neurology, Ospedale Pediatrico Bambino Gesu, Roma (Italy); Gobbi, G. [Dept. of Paediatric Neurology, Ospedale Maggiore Pizzardi, Bologna (Italy); Capovilla, G. [Dept. of Paediatric Neurology, Ospedale Poma, Mantova (Italy); Tassi, L. [Dept. of Epilepsy Surgery, Ospedale Niguarda Ca' Granda, Milano (Italy); Viri, M. [Epilepsy Centre, Ospedale Fatebenefratelli-Oftalmico, Milano (Italy); Giordano, L. [Dept. of Paediatric Neurology, Ospedale Civile, Brescia (Italy); Bernardina, B.D. [Dept. of Paediatric Neurology, Policlinico Borgo Roma, Verona (Italy); Spreafico, R. [Dept. of Neurophysiology, Ist. Nazionale Neurologico ' ' C. Besta' ' , Milano (Italy)

    2003-03-01

    Rasmussen's encephalitis (RE) is a rare, progressive, chronic encephalitis characterised by drug-resistant epilepsy, progressive hemiparesis and mental impairment. It typically involves only one cerebral hemisphere, which becomes atrophic. We present neuroradiological findings in 13 children with RE. MRI was performed in all patients, fluorodeoxyglucose positron-emission tomography (PET) in three, Tc-99m hexamethylpropylenamine oxime single-photon emission computed tomography (SPECT) in two and proton MR spectroscopy ({sup 1}HMRS) in two. MRI showed progression of the hemisphere atrophy, always prevalent in the region primarily involved (13 patients), spread of the abnormal signal in white matter (11) and cortex (10) and progression of atrophy of the head of the caudate nucleus (nine). Associated secondary changes were: atrophy of the contralateral cerebellar hemisphere (in four patients), the ipsilateral hippocampus (in five) and the brain stem (in five). The earliest CT and MRI abnormalities, seen between 1 day and 4 months after the first seizure (in 12 patients examined, nine of whom had MRI) in one cerebral hemisphere included: high signal on T2-weighted images in the cortex (seven patients) and white matter (nine), cortical atrophy usually involving the frontoinsular region, with mild or severe enlargement of the lateral ventricle (eight) and moderate atrophy of the head of the caudate nucleus (seven). (orig.)

  11. 白芍的中药代谢特征谱研究%Studies on metabolism of Chinese materia medica of radix from Paeonia lactiflora Pall

    Institute of Scientific and Technical Information of China (English)

    潘艳丽; 董玲; 刘洋; 石任兵; 徐暾海; 翟华强; 赵保胜; 方敏; 汪国鹏

    2011-01-01

    Objective To research the metabolism of components in the Radix of Paeonia lactiflora Pall. Methods (①) we established the HPLC fingerprint of water extract of Paeonia lactiflora Pall. and real-time monitored the chemical composition. (②) We established the HPLC fingerprint of rats' serum samples from hepatic portal vein, serum samples from aorta abdominalis and samples of intestinal absorption of Paeonia lactiflora Pall. (③) On this basis, using the established methods, I-IPLC fingerprint spectrum of serum samples,the sample of herb, the sample after intestinal metabolism, rats' serum samples from hepatic portal vein and rats'serum samples from aorta abdominalis were analyzed and compared in order to infer the metabolism of components in the Radix of Paeonia lactiflora Pall. Results 24 compositions were detected, seven of which were metabolized by intestinal flora and could not be absorbed into blood; six of them could not be absorbed directedly into intestinal; eight new compounds were absorbed into blood after bowel metabolism while they were not detected in water extract in Paeonia lactiflora Pall. Conclusion We could infer the metabolic processes of chemicals of Paeonia lactiflora Pall. in oral administration with this method.%目的 探讨芍药Paeonia lactiflora Pall.的干燥根中紫外可检出成分在大鼠体内的代谢过程。方法 ①运用HPLC-DAD技术,建立白芍水提物化学成分特征谱,进行其中总体化学成分的并行即时监测;②采用门静脉采血、腹主动脉采血、离体外翻肠囊法,建立白芍水提物入血成分、血中成分及肠吸收成分特征谱;③在相同色谱条件下,分析比较大鼠门静脉入血成分、腹主动脉血中成分及肠吸收成分的化学成分特征谱,推断白芍水提取物中化学成分的代谢过程。结果在分析的24种成分中,白芍中的6种成分不能被肠直接吸收:8种成分可被肠道直接吸收入血;7种成分被肠道

  12. Microbial growth on pall rings: a problem when upgrading biogas with the water-wash absorption technique.

    Science.gov (United States)

    Tynell, Asa; Börjesson, Gunnar; Persson, Margareta

    2007-01-01

    Biogas is upgraded using an absorption with water-wash technique by 11 of a total of 14 upgrading plants in Sweden. However, problems with microbial growth on the pall rings in the absorption column, and in one case in the desorption column, have a negative impact on the upgrading of raw gas to vehicle gas. Five of the nine biogas plants studied here have experienced problems with microbial growth. The objectives of this study were to identify such microbial growth and to determine possible factors for its control, in order to provide recommendations for process management. A questionnaire was sent out and visits were made to the upgrading plants to collect information about the upgrading process. Phospholipid fatty acid (PLFA) analysis was performed to determine microbial biomass and community structure in samples from four upgrading plants. In samples from two of the plants, methane-oxidizing bacteria (type I methanotrophs) were indicated, while samples from one of the other plants showed biomarkers indicating actinomycetes. Factors affecting development of microbial growth were found to be water quality and the pH and temperature of the process water. Plants that used wastewater in the upgrading process experienced far more problems than those using clean water of drinking quality.

  13. Ex situ conservation of genetic resources of field elm (Ulmus minor Mill and European white elm (Ulmus laevis Pall

    Directory of Open Access Journals (Sweden)

    Aleksić Jelena

    2004-01-01

    Full Text Available Principles of the conservation of genetic resources of elms (Ulmus spp do not differ fundamentally from the general principles accepted for the conservation of genetic resources of other common Noble Hardwoods. Efficient conservation can best be achieved through appropriate combination of in situ and ex situ methods, which have distinct advantages. Besides that, ex situ conservation is employed when emergency measures are needed for rare endangered populations and when populations are too small to be managed in situ (e.g. risks of genetic drift and inbreeding. The aim of our research is ex situ conservation of genetic resources of field elm {Ulmus minor Mill and European white elm (Ulmus laevis Pall through establishment of field genebanks. Sampling was conducted in one population of field elm and one population of white elm. Plant material (buds from 8 trees of field elm and 10 trees of white elm was used for in vitro production of clones. Obtained clones will be used for establishment of field genebanks on the experimental estate of the Institute of Lowland Forestry and Environment.

  14. 白芍化学成分及质量评价方法研究进展%Research Progress on Chemical Composition and Quality Control of Paeonia Lactiflora Pall

    Institute of Scientific and Technical Information of China (English)

    吴芳; 杜伟锋; 徐姗姗; 葛卫红; 来平凡

    2012-01-01

    The present single -index evaluation method of Paeonia actiflora Pall is too unilateral to reflect the inner quality of Paeonia lactiflora Pall comprehensively.This paper has reviewed the studies on chemical composition and quality control method and analytical technology of Paeonia lactiflora Pall in recent years in summary analysis.We focus on the multi-index evaluation method to control the quality of Paeonia lactiflora Pall,and put forward some new ideas to further improve the quality control of Paeonia lactiflora Pall.%现有的白芍的单指标评价方法,过于片面,不能全面的反映白芍的内在品质.作者通过对近几年来国内外文献的查阅,总结了白芍的化学成分、质量控制方法和分析技术,提出了采用多指标质量控制方法来控制白芍质量,为进一步完善白芍质量控制提供思路.

  15. POE增韧改性尼龙11复合材料流变性能的研究%Study on Rheological Property of PAll Composites Toughened by POE

    Institute of Scientific and Technical Information of China (English)

    郭云霞; 胡国胜; 牛慧军

    2011-01-01

    The rheological properties of PAll and its composites with POE were studied by using capillary rheometer. The results showed that PAll and its blend system are pseudoplastic fluids. The non-Newtonian indexes of the blend systems decrease remarkably when POE and POE-g-MAH are added in PAll. With the increase of POE-g-MAH content, the viscosities of the systems gradually rise.The viscous activation energy of PAll and POE blends decline as the increase of shearing stress, which indicate that the PAll and POE blend can be processed over a wide temperature at a high shearing stress.%采用毛细管流变仪研究了尼龙11(PA11)与POE复合材料的流变性能,结果表明:PA11及其与POE共混体系均属于假塑性流体,引入POE和POE-g-MAH增加了共混体系的非牛顿性,且随POE-g-MAH含量的增大,共混体系的表观粘度逐渐增大.PA11与POE共混体系的粘流活化能随着剪切应力的增大而降低,说明其在高剪切应力下可在较宽的温度范围内加工成型.

  16. Metabolomics coupled with multivariate data and pathway analysis on potential biomarkers in cholestasis and intervention effect of Paeonia lactiflora Pall.

    Directory of Open Access Journals (Sweden)

    Xiao eMa

    2016-02-01

    Full Text Available Background: The dried root of Paeonia lactiflora Pall. (PLP is a classical Chinese herbal medicine that has been used to treat hepatic disease for thousands of years. Our previous work suggested that PLP can be used to treat hepatitis with severe cholestasis. This study explored the mechanism by which PLP affects ANIT-induced cholestasis in rats using a metabolomics approach.Methods: The effects of PLP on serum indices (TBIL, DBIL, AST, ALT, ALP and TBA and the histopathology of the liver were analyzed. Moreover, UHPLC-Q-TOF was performed to identify the possible effect of PLP on metabolites. The pathway analysis was conducted to illustrate the pathways and network by which PLP treats cholestasis. Result: High-dose PLP remarkably down-regulated the serum indices and alleviated histological damage to the liver. Metabolomics analyses showed that the therapeutic effect of high-dose PLP is mainly associated with the regulation of several metabolites, such as glycocholic acid, taurocholic acid, glycochenodeoxycholic acid, L(D-arginine and L-tryptophan. A pathway analysis showed that the metabolites were related to bile acid secretion and amino acid metabolism. In addition, the significant changes in bile acid transporters also indicated that bile acid metabolism might be involved in the therapeutic effect of PLP on cholestasis. Moreover, a principal component analysis indicated that the metabolites in the high-dose PLP group were closer to those of the control, whereas those of the moderate dose or low-dose PLP group were closer to those of the ANIT group. This finding indicated that metabolites may be responsible for the differences between the effects of low-dose and moderate-dose PLP. Conclusions: The therapeutic effect of high-dose PLP on cholestasis is possibly related to regulation of bile acid secretion and amino acid metabolism. Moreover, these findings may help better understand the mechanisms of disease and provide a potential therapy for

  17. Correlations Between Foliar Stable Carbon Isotope Composition and Environ-mental Factors in Desert Plant Reaumuria soongorica (Pall.) Maxim.

    Institute of Scientific and Technical Information of China (English)

    Jian-Ying MA; Tuo CHEN; Wei-Ya QIANG; Gang WANG

    2005-01-01

    Leaves of 407 individuals of Reaumuria soongorica (Pall.) Maxim. collected from the major distribution areas were measured to investigate the distribution characteristics of the stable carbon isotope in this desert plant, as well as correlations between δ13C values and environmental factors. Results showed that δ13C values in R. soongorica ranged from-22.77‰. to-29.85‰. and that the mean δ13C value (-26.52‰)was higher than a previously reported δ13C value for a different desert ecosystem. This indicates that R.soongorica belongs to the C3 photosynthetic pathway and has higher water use efficiency than other species. The correlations between δ13C values and environmental factors demonstrated that the foliar δ13C values in R. soongorica increased significantly with decreasing mean annual precipitation and mean relative humidity, and decreased with decreasing duration of sunshine and evaporation. The spatial distribution trend of δ13C values in R. soongorica was not obvious and there was no significant correlation between the δ13C values and mean annual temperature. We conclude that different distribution trends in δ13C values for R. soongorica were likely caused by stomatal limitation rather than by nutrient-related changes in photosynthetic efficiency and that precipitation played an important role in the wide distribution range of R.soongorica. This pattern of δ13C values for R. soongorica reinforced that it is a super-xerophil in terms of its adaptive strategies to a desert environment.

  18. Identification of miRNAs Responsive to Botrytis cinerea in Herbaceous Peony (Paeonia lactiflora Pall. by High-Throughput Sequencing

    Directory of Open Access Journals (Sweden)

    Daqiu Zhao

    2015-09-01

    Full Text Available Herbaceous peony (Paeonia lactiflora Pall., one of the world’s most important ornamental plants, is highly susceptible to Botrytis cinerea, and improving resistance to this pathogenic fungus is a problem yet to be solved. MicroRNAs (miRNAs play an essential role in resistance to B. cinerea, but until now, no studies have been reported concerning miRNAs induction in P. lactiflora. Here, we constructed and sequenced two small RNA (sRNA libraries from two B. cinerea-infected P. lactiflora cultivars (“Zifengyu” and “Dafugui” with significantly different levels of resistance to B. cinerea, using the Illumina HiSeq 2000 platform. From the raw reads generated, 4,592,881 and 5,809,796 sRNAs were obtained, and 280 and 306 miRNAs were identified from “Zifengyu” and “Dafugui”, respectively. A total of 237 conserved and 7 novel sequences of miRNAs were differentially expressed between the two cultivars, and we predicted and annotated their potential target genes. Subsequently, 7 differentially expressed candidate miRNAs were screened according to their target genes annotated in KEGG pathways, and the expression patterns of miRNAs and corresponding target genes were elucidated. We found that miR5254, miR165a-3p, miR3897-3p and miR6450a might be involved in the P. lactiflora response to B. cinerea infection. These results provide insight into the molecular mechanisms responsible for resistance to B. cinerea in P. lactiflora.

  19. 不同贮藏年限白芍的化学成分分析%Chemical composition analysis of Paeonia lactiflora Pall.of different storage time

    Institute of Scientific and Technical Information of China (English)

    魏香兰; 万颖; 方如塘; 魏堂昇; 冀爱云

    2012-01-01

    目的 比较不同贮藏年限白芍的化合物含量变化.方法 采用HPLC法,测定不同贮藏年限的白芍中芍药苷、芍药苷亚硫酸酯、芍药内酯苷和没食子酸的含量.结果 芍药苷、芍药苷亚硫酸酯的含量变化与贮藏时间长短无明显相关性,芍药内酯苷含量随贮藏时间的延长存在降低的趋势,没食子酸含量变化不明显.结论 白芍可贮藏的年限较长,但采用硫磺熏蒸会大大降低芍药苷的含量.%Objective To comparc the chemical composition change in Paeonia lacliflora Pall, of different storage time. Methods Paeonia lacliflora Pall, of different storage time were determined by HPLC method with paconiflorin, paeonifiorin sulfite ester, albifiorin and gallic acid as the standards. Results The contents change of paconif1orin,paconif1orin suifite ester did not have obvious correlation'with the storage time, the content of albiflorin gradually decreased with storage period,and the content of gallic acid did not have significant change. Conclusions Paeonia lacliflora Pall, stores time is long,but sulphur fumigation will greatly reduce the content of paconiflorin.

  20. 白芍化学成分的UPLC/Q-TOF-MS分析%Analysis on chemical constituents of Paeonia lactiflora Pall.by UPLC/Q-TOF-MS

    Institute of Scientific and Technical Information of China (English)

    母会丹; 朱靖博; 丁燕; 寇自农; 王振中; 萧伟

    2013-01-01

    采用超高压液相色谱-飞行时间质谱(UPLC/Q-TOF-MS)在正离子、负离子模式下分析了白芍(Paeonia lactiflora Pall.)甲醇提取物中的化学成分.液相色谱分离条件为:色谱柱:Waters ACQUITYTM UPLC BEH C18(100×2.1mm,1.7μm),乙腈和0.1%甲酸水溶液梯度洗脱,体积流量为0.2 mL/min,质谱条件为:Waters ACQUITY Q-TOF-MS质谱仪,电喷雾接口,正、负离子模式检测.共推测出9个化合物的化学结构,分别为没食子酰基蔗糖,芍药苷亚硫酸酯,芍药内酯苷,芍药苷,没食子酰芍药苷及其3种同分异构体和苯甲酰芍药苷.探讨总结了芍药苷类化合物可能的裂解方式.%An ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometric (UPLC/QTOF-MS) method was established to analyze chemical constituents of the methanol extract of Paeonia lactiflora Pall.in positive and negative modes.The chromatographic separation was performed on a Waters ACQUITYTM UPLC BEH C18(100 × 2.1 mm,1.7 μm) using a mobile phase consisting of 0.1% formic acid water solution (A) and acetonitrile (B).The flow rate was 0.2 mL/min.The mass spectrometer was Waters ACQUITY QTOF-MS equipped with an electrospray ionization (ESI) interface in negative and positive modes.The chemical constituents of Paeonia lactiflora Pall.were well isolated and detected by this method.9 compounds were identified,and they were galloylsucrose,paeoniflorin sulfonate,albiflorin,paeoniflorin,galloylpaeoniflorin and its isomers,benzoylpaeoniflorin.The fragmentation pathway of paeoniflorin and albiflorin was inferred referring to the possible fragmentation.The results showed that the method was simple and rapid for the identification of the chemical constituents of Paeonia lactiflora Pall.

  1. Population genetic structure and mating system in the hybrid zone between Pinus sibirica Du Tour and P. pumila (Pall.) Regel at the Eastern Baikal Lake shore

    OpenAIRE

    E. A. Petrova; S. N. Goroshkevich; Y.S. Belokon; D.V. Politov

    2013-01-01

    Genetic structure of sympatric Pinus sibirica Du Tour and P. pumila (Pall.) Regel populations and putative interspecific hybrids between them was analyzed in the Baikal Lake region (Barguzin Biosphere Natural Reserve, Davsha River basin) by means of 31 allozyme loci controlling 18 enzyme systems. Several alleles at loci Adh-1, Fest-2, Lap-3, Pgi-1, Sod-3 and Skdh-1 were diagnostic for P. sibirica, while alleles typical for P. pumila were detected at loci Gdh, Got-3, Lap-3, Mdh-2, Mdh-4, Pepca...

  2. Role Models on Dope

    DEFF Research Database (Denmark)

    Christiansen, Ask Vest; Gleaves, John

    2014-01-01

    Compared to football-players cyclists are virtuous role models. Yes, Lance Armstrong, Michael Rasmussen and other riders have doped, and because of this they have received the predicate as the most immoral athletes in the sporting world. But if morality is not only a question of whether a person...

  3. "Jamil Perkersen Nielsen Rasmussen"

    DEFF Research Database (Denmark)

    Nørreby, Thomas Rørbeck

    Denne afhandling omhandler en ung mand fra Amager ved navn Jamil og hans sociale og sproglige praksisser. I min undersøgelse fokuserer jeg på, hvorledes Jamil konstruerer og forhandler etniske identiteter i skole- og fritidsmiljøer og på Facebook. Min undersøgelse er baseret på et etnografisk fel...

  4. Cultivating Erect Milkvetch (Astragalus adsurgens Pall.) (Leguminosae) Improved Soil Properties in Loess Hilly and Gullies in China

    Institute of Scientific and Technical Information of China (English)

    WANG Zhan-bin; WANG Qing-yi

    2013-01-01

    Erect milkvetch (Astragalus adsurgens Pall.), a leguminous grass, is a major source of fuel and forage, and has an important role in the restoration of the degraded ecosystems in central and northeastern China. The objective of this work was to investigate how erect milkvetch planting would affect the physical and chemical properties of soil in degraded arable lands. Soil samples at the depths of 0-20 and 20-40 cm were collected from erect milkvetch planting fileds at ages of 0, 1, 2 and 3 yr. Changes in soil bulk density, soil porosity, total N and P, organic matter content, available P, hydrolysable N and available K were measured. The results showed that root biomass and above-ground plant biomass were both significantly increased with plantation age. The significant increase in root nodule biomass was not observed in the first two years. However, it was significantly increased after three years. Root growth of erect milkvetch improved soil structure, and hence, decreased soil bulk density and increased soil porosity. Furthermore, the nitrogen fixation by erect milkvetch and return of erect milkvetch plant to soil increased the soil total N, hydrolysable N and organic matter content of the soil. Low concentrations of P in the soil with erect milkvetch planting could be ascribed to high plant uptakes and possibly to high sequestrations of P in plant biomass. Concentrations of K significantly increased during the first two years of erect milkvetch planting. The high accumulation of K under erect milkvetch cultivation in the first two years could partly be attributed to low plant uptake, and partly to relatively quick recycling within plant-soil systems. Three years after erect milkvetch plantingr, K accumulation at 0-20 cm soil layer was significantly lower than that from non-vegetated field sites, which could be attributed to high plant uptake. These parameters, except for soil bulk density, were all decreased with increasing soil depth. Soil total N, organic

  5. Fast and Accurate Identification of Cross-Linked Peptides for the Structural Analysis of Large Protein Complexes and Elucidation of Interaction Networks. / Tahir, Salman; Bukowski-Wills, Jimi-Carlo; Rasmussen, Morten; Rappsilber, Juri

    DEFF Research Database (Denmark)

    Rasmussen, Morten

    Fast and Accurate Identification of Cross-Linked Peptides for the structural analysis of large protein complexes and to elucidate interaction networks. Salman Tahir Jimi-Carlo Bukowski-Wills; Morten Rasmussen; Juri RappsilberWellcome Trust Centre for Cell Biology, Edinburgh , United Kingdom   Novel...

  6. Rasmussen脑炎患者临床表现及脑电图特点分析%Analysis of Clinical Features and EEG Characteristics of Rasmussen Encephalitis Patients

    Institute of Scientific and Technical Information of China (English)

    蒋萍; 郑丽华; 刘骅

    2016-01-01

    Objective To investigate the clinical features and electroencephalogram( EEG) characteristics of Rasmussen encephalitis( encephalitis Rasmussen,RE) in children. Methods The clinical data of 8 children with RE were analyzed retrospec-tively. Results 8 cases of children with an average age of 7 years old and two months in this group were with partial or compre-hensive epilepsy repeated hair as a start,all of the progress of chronic progressive focal epileptic state( EPC) ,with progressive cog-nitive impairment,language dysfunction and hemiplegia. The background activity of VEEG was a slow wave activity in one hemi-sphere or bilateral various guided slow wave activity based on one side hemisphere. The onset interval of VEEG was mostly bilateral hemisphere or unilateral hemisphere dominated by bilateral spinal spikes,spike slow wave,and multiple spike slow wave discharge. Conclusions RE is a kind of epilepsy syndrome with characteristic clinical manifestation and EEG change. And to improve the understanding of the disease is helpful for the early diagnosis.%目的:探讨Rasmussen脑炎( Rasmussen encephalitis,RE)患儿的临床表现和脑电图( EEG)特点。方法回顾性分析8例RE患儿的临床资料。结果本组8例患儿平均发病年龄7岁2月,以反复部分性或全面性癫痫发作起始,均进展为慢性进行性局灶性癫痫持续状态(EPC),伴进行性认知功能障碍、语言功能障碍以及偏瘫。 VEEG背景活动为一侧半球慢波活动或一侧半球为主的双侧各导慢波活动;VEEG发作间期大多为一侧半球或一侧半球为主的双侧各导棘波、棘-慢波、多棘-慢波放电。结论 RE系一种具有特征性的临床表现及脑电图变化的癫痫综合征,提高对该病的认识有助于早期诊断治疗。

  7. Experimental Study on Paeonia Lactiflora Pall Taken as Low Tension Gastrointestinal Contrast Agent%白芍作为低张力胃肠造影药物的实验研究

    Institute of Scientific and Technical Information of China (English)

    朱力萤; 李雅杰; 贾玉石; 刘鹭鸶

    2014-01-01

    目的:探讨白芍作为低张力胃肠造影药物的可行性。方法:实验分为空白组、阳性对照组、白芍低中高剂量组;采用小鼠碳末排出实验、小肠推进实验和豚鼠离体回肠运动实验观察白芍水提液对肠运动的影响。结果:白芍中高剂量均能够延迟小鼠碳末排出时间,降低小肠推进率,增加豚鼠离体回肠平滑肌振幅变化。结论:白芍具有减慢肠蠕动、松弛肠平滑肌作用,具有作为低张力胃肠造影剂的可行性。%Objective:To explore the feasibility of Paeonia lactiflora Pall was taken as low tension gastroin-testinal contrast agent .Methods: Experiment was divided into control , positive control and low , middle, high dose Paeonia lactiflora Pall groups .Carbon discharge and small intestinal propelling experiment in mice and movement of guinea pigs'isolated ileumwere applied to observe the effects of Paeonia lactiflora Pall water extract on intestinal movement .Results:Paeonia lactiflora Pall of middle and high dose could delay carbon discharge time in mice, reduce the advance rate of mice'small intestinal propelling and increase the changes of amplitude of guinea pigs'isolated ileum smooth muscle .Conclusion: Paeonia lactiflora Pall can slow bowel movement and relax intestinal smooth muscle , which can be taken as low tension gastrointestinal contrast agent to apply .

  8. Determination of Mineral Elements Utilization of Paeonia lactiflora Pall by ICP-AES%ICP-AES法检测芍药对矿质元素的吸收利用

    Institute of Scientific and Technical Information of China (English)

    简在友; 王文全; 李卫东; 孟丽; 许桂芳; 王秋玲; 王丹

    2011-01-01

    The contents of K, Ca, Na, Mg, Fe, Cu and so on in the roots of Paeonia lactiflora Pall and in the soil in which they grew were determined by ICP-AES technique to study the mineral elements utilization of P. Lactiflora Pall. The results indicate that the elements utilization rate of P. Lactiflora Pall is different in different locations, so the contents of mineral elements in the roots of P. Lactiflora Pall and even the quality of medicinal materials coming from them in different locations are different The contents of Ca, Fe, Zn and so on in Chi Shao in Heilongjiang and Inner Mongolia are relatively high. The contents of mineral elements in soil influence not only themselves' utilization but also other mineral elements utilization of P. Lactiflora Pall.%为了分析芍药对土壤矿质元素的吸收利用规律,采用ICP-AES法检测了不同产地芍药根和相应土壤中K,Ca,Na,Mg,Fe,Cu等主要矿质元素含量.结果表明:不同产地的芍药对土壤中矿质元素的吸收利用效率不同,反映在不同产地的芍药根中有些矿质元素含量有明显差异,从而使各地芍药药材质量在矿质元素方面也有差异,以黑龙江和内蒙古等地的赤芍中Ca,Fe,Zn等元素含量偏高;土壤中有些矿质元素不仅影响芍药对这种元素的吸收利用,而且影响芍药对其他元素的吸收利用.

  9. Morphing patient-specific musculoskeletal models

    DEFF Research Database (Denmark)

    Rasmussen, John; Galibarov, Pavel E.; Al-Munajjed, Amir

    other conditions may require CT or MRI data. The method and its theoretical assumptions, advantages and limitations are presented, and several examples will illustrate morphing to patient-specific models. [1] Carbes S; Tørholm S; Rasmussen, J. A Detailed Twenty-six Segments Kinematic Foot model...

  10. Isolation and structure identification of chemical principles from Paeonia Lactiflora Pall.%赤芍化学成分的分离与结构鉴定

    Institute of Scientific and Technical Information of China (English)

    王彦志; 石任兵; 刘斌

    2006-01-01

    目的研究毛茛科植物芍药(Paeonia lactiflora Pall.)的化学成分.方法应用色谱技术分离纯化,NMR、MS等波谱方法解析化学结构.结果从赤芍中分离出9个化合物,分别鉴定为:芍药苷(Ⅰ),羟基芍药苷(Ⅱ),苯甲酰芍药苷(Ⅲ),芍药新苷(Ⅳ),4-乙基-芍药苷(Ⅴ),邻苯三酚(Ⅵ),二氢芹菜素(Ⅶ),苯甲酸(Ⅷ),β-谷甾醇(Ⅸ).结论化合物Ⅴ、Ⅵ和Ⅶ为首次从赤芍中分离得到.

  11. 白芍中芍药苷的提取工艺研究%Study on extraction process of paeoniflorin from Paeonia lactiflora Pall

    Institute of Scientific and Technical Information of China (English)

    阎星如; 李英杰; 田杰

    2014-01-01

    Percolation method is used to extract paeoniflorin from Paeonia lactiflora Pall. Referring to the content of Paeoniflorin, orthogonal design was applied for optimum extraction process. The orthogonal experiment, the optimum extraction process conditions: soaking 24 hours in 15 volumes 70% ethanol percolation process can get a higher extraction rate of paeoniflorin.%采用渗漉法对白芍中芍药苷进行提取,以芍药苷为指标,用正交试验采用3因素3水平对工艺进行优化,得到的较佳工艺条件为浸渍24 h,用15倍体积70%的乙醇渗漉提取可以获得较高的芍药苷提取率。

  12. Uniform Design for Optimizating Regeneration Shoots Directly from Tender Leaves and Plant Regeneration System of Rhododendron chrysanthum Pall.%基于均匀设计优化牛皮杜鹃嫩叶直接再生芽苗及植株再生体系

    Institute of Scientific and Technical Information of China (English)

    李玉梅; 姜云天; 孙智慧

    2008-01-01

    [Objective] The experimental was aimed to screen the optimum regeneration shoot induction media and rooting media for tender leaves of Rhododendron chrysanthum Pall.[Method] The tender leaves of Rhododendron chrysanthum Pall were taken as explants to select the optimum bud induction media and rooting media through uniform design and the screening results were verified.[Result] The optimum media for regeneration shoot of Rhododendron chrysanthum Pall contained 1/4 MS,3.70 mg/L ZT, 0.02 mg/L IAA and 1.00 mg/L KT and its induction rate was 95.5% and the rooting media contained modified MS, 0.10 mg/L IAA and 0.07 mg/L NAA and its rooting rate was 98%. [Conclusion] Through this experiment, regeneration systems for regeneration shoot and regenerated plant from tender leaves of Rhododendron chrysanthum Pall were created successfully.

  13. 超声辅助水代法提取芍药籽油工艺条件优化%Optimization of ultrasound-assisted aqueous extraction of oil from Paeonia lactiflora Pall. seed

    Institute of Scientific and Technical Information of China (English)

    2016-01-01

    研究超声辅助水代法提取芍药籽油的工艺条件,并对其脂肪酸组成进行分析.研究了超声时间、液料比、超声功率和超声温度4个主要因素对芍药籽出油率的影响.在单因素试验的基础上,采用响应面法对超声辅助水代法提取工艺进行了优化.优化后的最佳提取工艺条件为:超声时间56 min,超声温度54℃,液料比8:1,超声功率885 W.在最佳工艺条件下,芍药籽出油率为27.99%.利用GC-MS分析芍药籽油脂肪酸组成,共鉴定出19种脂肪酸,主要脂肪酸为亚麻酸(48.01%)、亚油酸(41.30%),总不饱和脂肪酸含量大于90%.%The process conditions of ultrasound-assisted aqueous extraction of oil from Paeonia lactiflora Pall. seed were studied, and fatty acid composition of the oil was analyzed. The effects of four factors on extraction rate of Paeonia lactiflora Pall. seed oil were studied, including ultrasonic time,ratio of liquid to solid, ultrasonic power and ultrasonic temperature. Based on single factor experiment, the extraction process of Paeonia lactiflora Pall. seed oil was optimized by response surface methodology. The optimal extraction conditions were obtained as follows:extraction time 56 min,extraction temperature 54℃,ratio of liquid to solid 8:1 and ultrasonic power 885 W. Under these conditions,the extraction rate of Paeonia lactiflora Pall. seed oil was 27. 99%. The fatty acid composition of Paeonia lactiflora Pall. seed oil was analyzed by GC-MS,and nineteen kinds of fatty acids were identified. The main fatty acids in Paeonia lactiflora Pall. seed oil were linolenic acid(48. 01%)and linoleic acid(41. 30%),and the total content of unsaturated fatty acids was above 90%.

  14. Unilateral holohemispheric central nervous system lesions associated with medically refractory epilepsy in the pediatric population: a retrospective series of hemimegalencephaly and Rasmussen's encephalitis.

    Science.gov (United States)

    Wang, Doris D; Benkli, Barlas; Auguste, Kurtis I; Garcia, Paul A; Sullivan, Joseph; Barkovich, A James; Chang, Edward F; Tihan, Tarik

    2014-12-01

    Cortical malformations and inflammatory encephalopathy are among common etiologies for medically refractory epilepsy in children. On rare occasions, lesions can affect an entire cerebral hemisphere while sparing the other; the 2 processes that can manifest in this manner are hemimegalencephaly (HME) and Rasmussen's encephalitis (RE). Although the clinical course and radiological appearance between the 2 disorders are distinct, there is occasional overlapping pathology between RE and cortical migration disorders. One question that arises from these observations is whether RE and HME, diseases with holohemispheric involvement but apparently different etiologies, have any overlapping characteristics. The authors performed a retrospective review of all patients with presumed diagnosis of HME or RE who underwent hemispherectomy at University of California, San Francisco, and reviewed their clinical presentation, imaging, and pathology data. The authors present the clinicopathological features of 14 pediatric patients with unilateral holohemispheric lesions associated with medically refractory epilepsy. Radiological and pathological assessment classified 7 of the patients as having hemimegalencephaly, while the other 7 were diagnosed as having RE. Four of the patients had unusual features suggestive of overlapping developmental and inflammatory (dual) pathology. All patients underwent hemispherectomies. Eight patients (57%) became seizure free (Engel Class I), 5 patients (36%) had rare seizures (Engel Class II), and 1 patient had significant seizure reduction (Engel Class III). Based on this case series, HME and RE can be distinguished on the basis of their radiological and histological appearance, even though some cases may have overlapping features. Hemispherectomy was effective at eliminating seizures for both HME and RE.

  15. Population genetic structure and mating system in the hybrid zone between Pinus sibirica Du Tour and P. pumila (Pall. Regel at the Eastern Baikal Lake shore

    Directory of Open Access Journals (Sweden)

    E.A. Petrova

    2013-12-01

    Full Text Available Genetic structure of sympatric Pinus sibirica Du Tour and P. pumila (Pall. Regel populations and putative interspecific hybrids between them was analyzed in the Baikal Lake region (Barguzin Biosphere Natural Reserve, Davsha River basin by means of 31 allozyme loci controlling 18 enzyme systems. Several alleles at loci Adh-1, Fest-2, Lap-3, Pgi-1, Sod-3 and Skdh-1 were diagnostic for P. sibirica, while alleles typical for P. pumila were detected at loci Gdh, Got-3, Lap-3, Mdh-2, Mdh-4, Pepca, Pgi-1, Pgd-2, Pgd-3, Pgm-1 and Pgm-2. All hybrids were heterozygous for the diagnostic Skdh-2 locus. Classification into hybrids and parental species using PCA analysis of multilocus allozyme genotypes had good correspondence with diagnoses made by morphological and anatomical analyses. Approximately 27% of embryos in P. pumila seeds had P. sibirica paternal contribution, and 8% of haplotypes in effective pollen pool combined alleles typical for P. pumila and P. sibirica, and therefore were classified as pollinated by the hybrids. About 83% of embryos in seeds from the hybrids most likely originated from fertilization by P. sibirica pollen, 14% from P. pumila and 3% from hybrid trees. This result favours the view that hybrids make both male and female contributions to the reproductive output of the population and confirm the presence of backcrosses and F2 hybrids.

  16. Population genetic structure and mating system in the hybrid zone between Pinus sibirica Du Tour and P. pumila (Pall. Regel at the Eastern Baikal Lake shore

    Directory of Open Access Journals (Sweden)

    E.A. Petrova

    2013-12-01

    Full Text Available Genetic structure of sympatric Pinus sibirica Du Tour and P. pumila (Pall. Regel populations and putative interspecific hybrids between them was analyzed in the Baikal Lake region (Barguzin Biosphere Natural Reserve, Davsha River basin by means of 31 allozyme loci controlling 18 enzyme systems. Several alleles at loci Adh-1, Fest-2, Lap-3, Pgi-1, Sod-3 and Skdh-1 were diagnostic for P. sibirica, while alleles typical for P. pumila were detected at loci Gdh, Got-3, Lap-3, Mdh-2, Mdh-4, Pepca, Pgi-1, Pgd-2, Pgd-3, Pgm-1 and Pgm-2. All hybrids were heterozygous for the diagnostic Skdh-2 locus. Classification into hybrids and parental species using PCA analysis of multilocus allozyme genotypes had good correspondence with diagnoses made by morphological and anatomical analyses. Approximately 27% of embryos in P. pumila seeds had P. sibirica paternal contribution, and 8% of haplotypes in effective pollen pool combined alleles typical for P. pumila and P. sibirica, and therefore were classified as pollinated by the hybrids. About 83% of embryos in seeds from the hybrids most likely originated from fertilization by P. sibirica pollen, 14% from P. pumila and 3% from hybrid trees. This result favours the view that hybrids make both male and female contributions to the reproductive output of the population and confirm the presence of backcrosses and F2 hybrids.

  17. Population genetic structure and mating system in the hybrid zone between Pinus sibirica Du Tour and P. pumila (Pall. Regel at the Eastern Baikal Lake shore

    Directory of Open Access Journals (Sweden)

    E.A. Petrova

    2008-09-01

    Full Text Available Genetic structure of sympatric Pinus sibirica Du Tour and P. pumila(Pall. Regel populations and putative interspecific hybrids between them was analyzed in the Baikal Lake region (Barguzin Biosphere Natural Reserve, Davsha River basin by means of 31 allozyme loci controlling 18 enzyme systems. Several alleles at loci Adh-1, Fest-2, Lap-3, Pgi-1, Sod-3 and Skdh-1 were diagnostic for P.sibirica, while alleles typical for P. pumila were detected at loci Gdh, Got-3, Lap-3,Mdh-2, Mdh-4, Pepca, Pgi-1, Pgd-2, Pgd-3, Pgm-1 and Pgm-2. All hybrids were heterozygous for the diagnostic Skdh-2 locus. Classification into hybrids and parental species using PCA analysis of multilocus allozyme genotypes had good correspondence with diagnoses made by morphological and anatomical analysis.Approximately 27% of embryos in P. pumila seeds had P. sibirica paternal contribution, and 8% of haplotypes in effective pollen pool combined alleles typical for P. pumila and P. sibirica, and therefore were classified as pollinated by the hybrids. About 83% of embryos in seeds from the hybrids most likely originated from fertilization by P. sibirica pollen, 14% from P. pumila and 3% from hybrid trees.This result favours the view that hybrids make both male and female contributions to the reproductive output of the population and confirm the presence of backcrosses and F2 hybrids.

  18. Petrography and Geochemistry (Trace, Ree and Pge of Pedda Cherlo Palle Gabbro-Diorite Pluton, Prakasam Igneous Province, Andhra Pradesh, India

    Directory of Open Access Journals (Sweden)

    Subramanyam K.S.V.

    2015-09-01

    Full Text Available Prakasam Igneous Province (PIP is an important geological domain in the Eastern Dharwar Craton (EDC, found in the junction zone between the EDC and Eastern Ghat Mobile Belt (EGMB. The Pedda Cherlo Palle (PCP gabbros are massive, leucocratic-mesocractic, and show cumulus textures with minerals plagioclase, cpx, and amphiboles. Compositionally, plagioclase is a labradorite-bytownite, cpx is diopside to augite, olivines are hyalosiderites and amphiboles are magnesiohornblendes. PCP gabbros have normal SiO2, high Al2O3, moderate to high TiO2, Na2O and medium Fe2O3, so, classified as subalkaline tholeiitic gabbros. Fractionated rare earth element (REE patterns, high abundance of large ion lithofile elements (LILE and transitional metals coupled with light REE (LREE relative enrichment over heavy REE (HREE and Nb are characteristics of partial melting of depleted mantle and melts that have undergone fractional crystalisation. These partial melts are enriched in LREE and LILE, due to the addition of slab derived sediment and fluids. PCP gabbros contain low abundance (5.1 to 24.6 ng/g of platinum group elements (PGE, and show an increase in the order Ir>Os>Pt>Ru»Pd>Rh. We propose that the subduction related intraoceanic island arc might have accreted to the southeastern margin of India to the east of Cuddapah basin in a collisional regime that took place during Ur to Rodinia amalgamations.

  19. Treatment of newly diagnosed Rasmussen encephalitis%9例初诊腊斯默森脑炎患者的临床探讨

    Institute of Scientific and Technical Information of China (English)

    费凌霞; 陈鑫浩; 刘新建; 张佩琪; 李花; 胡湘蜀; 郭强

    2016-01-01

    目的:通过初诊腊斯默森脑炎(Rasmussen encephalitis,RE)患者的临床处理过程,明确治疗方法的选择.方法:按照欧洲共识的诊断标准,初诊RE 9例.分析患者的病史、病程、发作特点、脑电图、MRI和PET表现,动态观察患者的MRI和PET,其中6例患者建议大脑半球切除手术治疗,3例患者建议颅脑病理活检.结果:所有患者均表现为一侧起始的部分性发作,多种发作形式,6例患者出现部分性癫(痫)持续状态(epilepsia partialis continua,EPC).就诊时7例患者有轻偏瘫.所有患者MRI均出现半球萎缩,PET示半球性或半球多灶性低代谢,脑电图示半球的慢活动.在临床处理上,4例行半球切除术,病理学检查支持RE诊断,其中2例合并局灶性皮质发育不良(FCD),为双重病理改变;另1例脑活检后排除RE.另外4例拒绝手术和脑活检.结论:对于初诊的RE患者,MRI及PET的动态观察是RE诊断的重要方法,脑手术组织病理学和脑活检亦可明确诊断.

  20. Paeonia lactiflora Pall. protects against ANIT-induced cholestasis by activating Nrf2 via PI3K/Akt signaling pathway

    Directory of Open Access Journals (Sweden)

    Ma X

    2015-09-01

    Full Text Available Xiao Ma,1,2 Yan-ling Zhao,2 Yun Zhu,3 Zhe Chen,1,2 Jia-bo Wang,4 Rui-yu Li,1,4 Chang Chen,1,2 Shi-zhang Wei,1,2 Jian-yu Li,3 Bing Liu,5 Rui-lin Wang,3 Yong-gang Li,3 Li-fu Wang,3 Xiao-he Xiao4 1Pharmacy College, Chengdu University of Traditional Chinese Medicine, Chengdu, People’s Republic of China; 2Department of Pharmacy, 302 Military Hospital of People’s Liberation Army, Beijing, People’s Republic of China; 3Department of Integrative Medical Center, 302 Military Hospital of People’s Liberation Army, Beijing, People’s Republic of China; 4China Military Institute of Chinese Medicine, 302 Military Hospital of People’s Liberation Army, Beijing, People’s Republic of China; 5School of Chinese Medicine, The University of Hong Kong, Hong Kong Background: Paeonia lactiflora Pall. (PLP, a traditional Chinese herbal medicine, has been used for hepatic disease treatment over thousands of years. In our previous study, PLP was shown to demonstrate therapeutic effect on hepatitis with severe cholestasis. The aim of this study was to evaluate the antioxidative effect of PLP on alpha-naphthylisothiocyanate (ANIT-induced cholestasis by activating NF-E2-related factor 2 (Nrf2 via phosphatidylinositol 3-kinase (PI3K/Akt signaling pathway. Materials and methods: Liquid chromatography-mass spectrometry (LC-MS was performed to identify the main compounds present in PLP. The mechanism of action of PLP and its therapeutic effect on cholestasis, induced by ANIT, were further investigated. Serum indices such as total bilirubin (TBIL, direct bilirubin (DBIL, aspartate aminotransferase (AST, alanine aminotransferase (ALT, alkaline phosphatase (ALP, γ-glutamyl transpeptidase (γ-GT, and total bile acid (TBA were measured, and histopathology of liver was also performed to determine the efficacy of treatment with PLP. Moreover, in order to illustrate the underlying signaling pathway, liver glutathione (GSH content and mRNA or protein levels of glutamate

  1. Digital Gene Expression Analysis to Screen Disease Resistance-Relevant Genes from Leaves of Herbaceous Peony (Paeonia lactiflora Pall. Infected by Botrytis cinerea.

    Directory of Open Access Journals (Sweden)

    Saijie Gong

    Full Text Available Herbaceous peony (Paeonia lactiflora Pall. is a well-known traditional flower in China and is widely used for landscaping and garden greening due to its high ornamental value. However, disease spots usually appear after the flowering of the plant and may result in the withering of the plant in severe cases. This study examined the disease incidence in an herbaceous peony field in the Yangzhou region, Jiangsu Province. Based on morphological characteristics and molecular data, the disease in this area was identified as a gray mold caused by Botrytis cinerea. Based on previously obtained transcriptome data, eight libraries generated from two herbaceous peony cultivars 'Zifengyu' and 'Dafugui' with different susceptibilities to the disease were then analyzed using digital gene expression profiling (DGE. Thousands of differentially expressed genes (DEGs were screened by comparing the eight samples, and these genes were annotated using the Gene ontology (GO and Kyoto encyclopedia of genes and genomes (KEGG database. The pathways related to plant-pathogen interaction, secondary metabolism synthesis and antioxidant system were concentrated, and 51, 76, and 13 disease resistance-relevant candidate genes were identified, respectively. The expression patterns of these candidate genes differed between the two cultivars: their expression of the disease-resistant cultivar 'Zifengyu' sharply increased during the early stages of infection, while it was relatively subdued in the disease-sensitive cultivar 'Dafugui'. A selection of ten candidate genes was evaluated by quantitative real-time PCR (qRT-PCR to validate the DGE data. These results revealed the transcriptional changes that took place during the interaction of herbaceous peony with B. cinerea, providing insight into the molecular mechanisms of host resistance to gray mold.

  2. Remote Medical Diagnosis System (RMDS) Advanced Development Model (ADM) Laboratory Test Results.

    Science.gov (United States)

    1982-01-01

    Develop- ment Model (AD[4) Test and Evaluacion Sumnary Report, WT Rasmussen and I Stevens (NOSC), April 1979. NOSC TNs are informal documents intended...shift was due to simple delay and that the integrity of the waveform was maintained in transmission. For this line, 57 0a 0 0o 0 4xe 000 00 00 E 0 000 a

  3. 基于HPLC技术分析白芍根茎与主根部分的主成分含量差异%Determination of paeoniflorin and albiflorin in taproot and rhizome of Paeonia lactiflora Pall.

    Institute of Scientific and Technical Information of China (English)

    郑金凤; 王景红; 宗志勇; 路广义

    2016-01-01

    Objective To determine the content of paeoniflorin and albiflorin in the different sample treatment of Paeonia lactiflora Pall. . Methods The HPLC method was used to detected, the chro-matographic condition was RP-C18 (4 mm×250 mm,5 μm) column with HCN-water(25 ∶ 75) as mobile phase, flow velocity was 1. 0 mL/min, with the detection wavelength was 230 nm, column temperature was 30℃. Results The content of paeoniflorin and albiflorin in taproot and rhizome of Paeonia lactiflora Pall. was increased after peeled. Whether boiled or peeled, the content of paeoniflorin and albiflorin in rhizome was higher than taproot of Paeonia lactiflora Pall. . Conclusion Rhizome of Paeonia lactiflora Pall. has the potential to use as medicinal parts, it could be exploited and used in further.%目的:采用高效液相色谱法检测亳芍不同的样品处理方法下主根和根茎部分芍药苷和芍药内酯苷的含量。方法采用高效液相色谱法,色谱条件:C18柱( phenomenex公司,250 mm ×4.6 mm,5μm);流动相:乙腈-水(25:75);检测波长为230 nm;柱温:30℃;流速为1.0 mL/min。结果经过煮制后的白芍去皮主根或根茎所含芍药苷和芍药内酯苷的总含量低于未煮制;白芍的主根和根茎部分去皮后芍药苷和芍药内酯苷总含量高于未去皮的主根和根茎;无论是否煮制,是否去皮,白芍根茎中芍药苷和芍药内酯苷的含量均高于主根。结论白芍根茎有作为药用部位的基础。

  4. Technique Refinement and Validation of Variable Aortic Occlusion via Extracorporeal Flow Circuit in a Pig Model (Sus scrofa) of Uncontrolled Hemorrhage with Subsequent Resuscitation and Critical Care

    Science.gov (United States)

    2016-07-24

    Rasmussen TE. Extending REBOA: Endovascular Variable Aortic Control (EVAC) in a Lethal Model of Hemorrhagic Shock. The Journal of Trauma and Acute Care...animals and minimized the ischemic insult to distal vascular beds, thus preserving organ viability as evidenced by early return of urine output and

  5. HPLC法双波长同时测定赤芍中4种成分的含量%HPLC Ddouble Wavelength Simultaneous Determination of Four Components in Paeonia lactiflora Pall

    Institute of Scientific and Technical Information of China (English)

    柳梦婷; 方婧; 孙昊; 吴宏伟; 付梅红; 杨洪军

    2014-01-01

    目的:采用高效液相色谱法,在不同检测波长下同时测定赤芍中儿茶素、芍药苷、苯甲酸、丹皮酚4种成分的含量。方法色谱柱为Diamonsil C185μm 250×4.6 mm,以0.1%甲酸-乙腈为流动相进行梯度洗脱,检测波长为230 nm (儿茶素、芍药苷、苯甲酸),275 nm(丹皮酚),流速1 mL·min-1,柱温30℃。结果不同产地赤芍中4种成分含量差异较大,7批不同产地赤芍药材中儿茶素、芍药苷、苯甲酸和丹皮酚的含量范围分别为:0%~0.052%、1.044%~4.326%、0.126%~0.249%、0.022%~1.060%。结论本法操作简便、准确、重复性好,可用于赤芍药材中儿茶素、芍药苷、苯甲酸、丹皮酚含量的测定。%Objective To establish a HPLC method for determining the content of catechin, paeoniflorin, benzoic acid and paeonol in Paeonia lactiflora Pall at different wavelength. Methods It was performed on Diamonsil colunm C18 μm 250×4.6 mm, mobile phase was 0.1%methanoic acid-methyl cyanide, gradient elute, detection wavelength was 230 nm (catechin, paeoniflorin, benzoic acid) and 275 nm (paeonol), flow rate was 1mL·min-1, and colunm temperature was 30℃. Results The contents of four active components in Paeonia Lactiflora Pall from different habitats were quite different. The contents of catechin, paeoniflorin, benzoic acid and paeonol were 0%~0.052%, 1.044~4.326%, 0.126~0.249%, 0.022~1.060%respectively. Conclusion The method is simple and accurate with good reproducibility, it is suitable for determining the contents of catechin, paeoniflorin, benzoic acid and paeonol in Paeonia lactiflora Pall.

  6. Breeding and Matching Technology of Suaeda salsa(L.﹚Pall. Greening Cultivation Strains%盐地碱蓬绿化栽培品系的选育与配套技术

    Institute of Scientific and Technical Information of China (English)

    邵秋玲; 谢小丁

    2014-01-01

    General saplings are not adapt to the saline-alkali soil and grow normally under the special soil conditions of the Yellow River Delta. This phenomenon has seriously hampered the afforestation and urban greening. Based on the detailed in-vestigation and researches of the local high salt tolerance of wild halophyte Suaeda salsa (L.﹚ Pall., a number of dominant plants adapting to severe saline were found. Through harvesting and planting alone, and generational purifying, two Suaeda salsa (L.﹚ Pall. greening cultivation strains tolerating salinity level of 2% or more were bred. Supporting cultivation techniques were studied to overcome the reliance on foreign soil greening coastal saline, form greening plant species with local charac-teristics, and enrich the biodiversity of the coastal saline areas.%黄河三角洲地区特殊的土壤条件导致一般苗木因不适应当地的盐碱地条件而不能正常生长,严重制约了造林及城市绿化。对当地耐盐程度高的野生耐盐植物盐地碱蓬[Suaeda salsa(L.)Pall.]进行详细调查和研究,发现了多个适宜重度盐碱地绿化的优势单株,通过单采单种,逐代纯合,选出了2个耐盐程度在2%以上的盐地碱蓬绿化栽培品系。研究了其配套栽培技术,在一定程度上克服了盐碱地依赖客土绿化的弊端,形成具有当地特色的绿化植物种类,丰富了盐碱地区的生物多样性。

  7. Extended UNIQUAC model for thermodynamic modeling of CO2 absorption in aqueous alkanolamine solutions

    DEFF Research Database (Denmark)

    Faramarzi, Leila; Kontogeorgis, Georgios; Thomsen, Kaj

    2009-01-01

    The extended UNIQUAC model [K. Thomsen, R Rasmussen, Chem. Eng. Sci. 54 (1999) 1787-1802] was applied to the thermodynamic representation of carbon dioxide absorption in aqueous monoethanolamine (MEA), methyldiethanolamine (MDEA) and varied strength mixtures of the two alkanolamines (MEA-MDEA). F......The extended UNIQUAC model [K. Thomsen, R Rasmussen, Chem. Eng. Sci. 54 (1999) 1787-1802] was applied to the thermodynamic representation of carbon dioxide absorption in aqueous monoethanolamine (MEA), methyldiethanolamine (MDEA) and varied strength mixtures of the two alkanolamines (MEA......) are included in the parameter estimation process. The previously unavailable standard state properties of the alkanolamine ions appearing in this work, i.e. MEA protonate, MEA carbamate and MDEA protonate are determined. The concentration of the species in both MEA and MDEA solutions containing CO2...

  8. Monitoring Protein Conformation Changes as an Activating Step for Protein Interactions with Cross-linking/MS Analysis. / Chen, Zhuo; Rasmussen, Morten; Tahir, Salman; Clark, C.A.C; Barlow, Paul; Rappsilber, Juri

    DEFF Research Database (Denmark)

    Rasmussen, Morten

    Monitoring protein conformation changes as an activating step for protein interactions with cross-linking/MS analysis. Chen, Zhou; Rasmussen, Morten; Tahir, Salman; Clark, C.A.C; Barlow, Paul; Rappsilber, Juri.   Introduction Protein interactions often require conformational changes in proteins....... Chemical cross-linking of proteins coupled with mass spectrometric analysis is emerging as a versatile tool for determining low-resolution three-dimensional structures of proteins. We show in this study that this technique is also able to resolve protein conformation changes, investigating the transition......-linked peptides and manual validation were performed using in-house software. The structural information determined by validated cross-links was compared against C3 and C3b crystal structure using Pymol.   Preliminary results We portray conformation changes from C3 to C3b through observing different group...

  9. 响应面试验优化微波法提取刺玫籽原花青素的工艺%Optimization of Microwave-Assisted Extraction of Proanthocyanidins from Rosa davurica Pall. Seeds by Response Surface Methodology

    Institute of Scientific and Technical Information of China (English)

    容晨曦; 张秀玲; 李铁柱; 胡济美; 张杰; 李倬林

    2016-01-01

    The microwave-assisted extraction of proanthocyanidins (PC) fromRosa davnrica Pall. seeds was optimized using the response surface methodology. The PC content ofRosa davnrica Pall. seeds was determined to be (1.55± 0.12) g/100 g by iron salt catalysis method. The results of one-factor-at-a-time experiments showed that the addition of 0.2% sodium hexametaphosphate (SH) provided the best stability for the proanthocyanidins. Extraction time, solid to liquid ratio, microwave power, and ethanol concentration were selected as independent variables, while the extraction yield of PC was taken as response variable. The optimization was carried out based on Box-Behnken experimental design by investigating the individual and combined effects of the four factors on the response variable. The optimum extraction conditions were determined as follows: extracting time, 70 s; material to liquid ratio, 1:20 (g/mL); microwave power, 360 W; and ethanol concentration, 60%. Under these conditions, the PC yield in one extraction cycle obtained was 72.58% with a relative error of 1.12% as compared with the model prediction of 73.46% indicating that these parameters are reliable. In first three cycles, 93.19% of the measured PC were extracted.%利用响应面分析,对微波法提取刺玫籽中原花青素工艺进行优化。采用铁盐催化法测定原花青素质量分数,结果表明刺玫籽中原花青素总含量为(1.55±0.12) g/100 g。单因素试验结果表明,六偏磷酸钠添加量为0.2%时能达到最佳稳定效果。在此基础上,选取提取时间、料液比、微波功率、乙醇体积分数为自变量,以原花青素提取率为响应值,采用Box-Behnken设计方法,研究各因素及其交互作用对原花青素提取率的影响。结果表明,最佳工艺参数为:提取时间70 s、料液比1∶20(g/mL)、微波功率360 W、乙醇体积分数60%。经验证,单次提取原花青素的提取率为72.58%,与预测值73.46%

  10. Thermodynamic modeling of the solubility of CO2 in aqueous alkanolamine solutions using the extended UNIQUAC model Application to monoethanolamine and methyldiethanolamine

    DEFF Research Database (Denmark)

    Faramarzi, Leila; Kontogeorgis, Georgios; Thomsen, Kaj;

    2009-01-01

    -water systems in a wide range of temperature (-20-200 degrees C) were used. The application of the model to a large number of experimental data for representation of total pressure over the absorbent solutions (25-200 degrees C), correlation of the excess enthalpy and freezing point depression of the binary......The extended UNIQUAC model as proposed by Thomsen and Rasmussen [K. Thomsen, P. Rasmussen, Chem. Eng. Sci. 54 (1999) 1787-1802] was applied to the thermodynamic representation of carbon dioxide absorption in aqueous monoethanolamine (MEA) and methyldiethanolamine (MDEA) solutions. All the essential...... parameters of the model are simultaneously regressed to a set of data on the MEA and MDEA systems. Freezing point depression, vapor liquid equilibrium (VLE) and excess enthalpy (H-E) data of the binary systems of MEA-water and MDEA-water, VLE data on the ternary CO2-MEA-water as well as CO2-MDEA...

  11. Investigated the Wild Resources of the Endangered Species Trillium kamtschaticum Pall .in Jiaohe City,Jilin Province%吉林省蛟河市濒危药用植物白花延龄草资源调查1)

    Institute of Scientific and Technical Information of China (English)

    刘继永; 邵财; 张浩; 曲正义

    2014-01-01

    To provide the references for setting up the measures of wild resources protection and sustain-able utilization of T .kamtschaticum Pall ,researching on the dangerous ecological mechanism ,By studied on the geographical distribution ,entironment ,Community types and unit area reserves of the wild re-sources of the endangered species T .kamtschaticum Pall .in Jiaohe City ,Jilin Province.%通过对吉林省蛟河市濒危药用植物白花延龄草野生资源的地理分布、生态环境、群落类型及单位面积蕴藏量等调查研究,为制定野生白花延龄草资源的保护与可持续利用措施,研究其致危生态机理,提供参考。

  12. Studies on morphological structure of leaves of Suaeda salsa(L.) Pall in two different saline environments%两种不同盐浓度环境中盐地碱蓬叶 的形态结构特征研究

    Institute of Scientific and Technical Information of China (English)

    章英才; 张晋宁

    2001-01-01

    通过光学显微镜和扫描电镜观察,研究了盐生植物盐地碱蓬叶的形态解剖学特征.结果表明,盐地碱蓬是典型的贮盐植物;生长在两种不同盐浓度环境中的盐地碱蓬,在叶外部形态及内部结构方面表现出显著的性状差异.%The morphological and anatomical features of leaves of halophyte Suaeda salsa (L.) Pall were observed and studied using microscope and scanning electron microscope. The results show that Suaeda salsa (L.) Pall is a typical salt store plant, which shows significant character difference in external morphology and internal structure of leaf in two different saline environments.

  13. 中药白芍愈伤组织的培养及其中芍药苷的测定%Study on Callus Culture of Paeonia lactiflora pall and Determination of Paeoniflorin in Callus

    Institute of Scientific and Technical Information of China (English)

    凌庆枝; 董丽辉; 章聪敏; 高莉莉; 江海龙; 冯定军; 周海滨

    2013-01-01

    [Objective] To establish the methods of callus culture,and determine the content of paeoniflorin in callus cells of Paeonia lactiflora pall.[Method] Leaves and stem sterilized were cut into tissue pieces and inoculated on different induction medium and regeneration medium.Paeoniflorin was extracted from callus and the content of paeoniflorin was determined by TLC and HPLC.[Result] The results showed that medium of 1/2MS + 0.2 mg/L 2,4-D + 2.0 mg/L 6-BA + 0.2 mg/L NAA were fit for stem callus induction,and medium of 1/2MS + 1.0 mg/L 2,4-D + 1.5 mg/L 6-BA were fit for leaves callus induction.Regeneration medium of callus is 1/2MS + 0.1 mg/L 2,4-D + 1.0 mg/L ZT + 0.5 mg/L NAA.The content of paeoniflorin of callus is 0.068 9 mg/g by HPLC.[Conclusion] Leaf and stem of Paeonia lactiflora pall could be induced to form callus.There are paeoniflorin in callus cells of Paeonia lactiflora pall.%[目的]建立中药白芍愈伤组织培养的方法,并测定其中芍药苷的含量.[方法]以白芍叶、茎为外植体,接种于不同的愈伤诱导培养基和继代培养基上培养愈伤组织,并提取愈伤组织中的芍药苷,用TLC和HPLC法测定愈伤组织中芍药苷的含量.[结果]适合白芍茎的诱导愈伤培养基是1/2MS +0.2 mg/L2,4-D +2.0 mg/L 6-BA +0.2 mg/L NAA,叶的最适诱导培养基是1/2MS+ 1.0 mg/L 2,4-D+ 1.5 mg/L 6-BA,白芍愈伤继代培养适合培养基为1/2MS +0.1 mg/L2,4-D+ 1.0 mg/L ZT +0.5 mg/L NAA.经HPLC测定每克干白芍愈伤组织中的芍药苷含量为0.068 9 mg.[结论]中药白芍的叶和茎可诱导形成愈伤组织,且形成的愈伤组织中含有芍药苷.

  14. 固相萃取-高效液相色谱-电喷雾串联质谱法分析芍药和酒芍药的水溶性化学成分%Analysis of Components in Aqueous of Paeonia Lactiflora Pall and Paeonia Lactiflora Pall Preparation with Wine by Solid Phase Extraction-High Performance Liquid ChromatographyElectrospray Ionization Mass Spectrometry

    Institute of Scientific and Technical Information of China (English)

    何忠梅; 孙佳明; 张辉; 王华

    2009-01-01

    利用固相萃取-高效液相色谱-电喷雾串联质谱法(SPE-HPLC-DAD-ESI-MS2)分析了芍药(Paeonia lactiflora Pall.)及其炮制品酒芍药(Paeonia lactiflora Pall.preparated with wine)水煎液中化学成分的种类和结构,并对其主要有效成分芍药苷进行了定量测定.用此方法得到了芍药和酒芍药水煎液的紫外色谱(UV)图、总离子流色谱(TIC)图和萃取离子色谱(EIC)图,以及相应色谱峰的紫外光谱图和EIC/MS2的质谱图.对其进行解析,发现芍药和酒芍药水煎液中所含化学成分基本一致,但酒芍药水煎液中除主要活性成分芍药苷含量基本未变外,其它酚酸性化学成分含量相对于芍药水煎液均有不同程度的下降.同时鉴别出芍药和酒芍药水煎液中共同含有的16种成分,它们分别是:蔗糖、(+)-儿茶素、Mudanpioside E、芍药新苷、芍药内酯苷、氧化芍药苷、芍药苷、羟基芍药苷、没食子酰芍药苷*、牡丹皮苷Ⅰ、苯甲酰芍药苷、三没食子酰葡萄糖、四没食子酰葡萄糖、五没食子酰葡萄糖.以上分析说明,酒炙可保留芍药的药效,同时"缓和其酸寒伐肝之性".

  15. Prediction of Mineral Scale Formation in Geothermal and Oilfield Operations using the Extended UNIQUAC Model. Part I: Sulphate Scaling Minerals

    DEFF Research Database (Denmark)

    Garcia, Ada V.; Thomsen, Kaj; Stenby, Erling Halfdan

    2005-01-01

    Pressure parameters are added to the Extended UNIQUAC model presented by Thomsen and Rasmussen (1999). The improved model has been used for correlation and prediction of solid-liquid equilibrium (SLE) of scaling minerals (CaSO4, CaSO4·2H2O, BaSO4 and SrSO4) at temperatures up to 300°C and pressures...

  16. 白刺果实提取物的体外抑菌活性研究%In vitro antimicrobial activity of extracts from fruits of Nitraria sibirica pall.

    Institute of Scientific and Technical Information of China (English)

    张桂霞; 齐敬浩; 任旭; 陈贵林

    2012-01-01

    Evaluated the in vitro antimicrobial activity of Nitraria sibirica Pall. Fruits extracts to provide the basis for utilizating Nitraria resources and developing natural food antiseptic. Nitraria sibirica Pall. fruits were extracted with 95% ethanol,then fractionated with petroleum ether,chloroform,ethyl acetate and n-butanol respectively. The filter paper disc diffusion method was performed to determine the influence of the different extracts on the growths of 3 bacterium(Escherichia coil, Bacillus subtilis, Staphyloccocus aureus) and 4 fungus(Penici//ium sp., Rhizopus sp. ,Aspergillus niger, Saccharomyces cerevisiae ) ,and the minimal inhibitory concentrations(MICs) of ethyl acetate extracts againts the 3 kinds of bacterium were tested using the doubling dilution method.The results showed that the ethyl acetate,ethanol and chloroform extracts had antibacterial activity against the 3 kinds of bacterium. In addition ,the ethyl acetate extracts presented higher antibacterial activity than others. The MIC of ethyl acetate extract against Escherichia coil, Bacillus subtilis, Staphyloccocus aureus were 25,25, 50mg/mL. None of the extracts exhibited inhibitory activity against Fungus.%探讨白刺果实提取物的体外抑菌活性,以期为白刺果实的综合利用及天然食品防腐剂的开发提供依据。用石油醚、氯仿、乙酸乙酯和正丁醇分别对白刺果实95%乙醇提取物进行萃取,纸片法测定各萃取部分对大肠杆菌、枯草芽孢杆菌、金黄色葡萄球菌、酵母菌、青霉、根霉和黑曲霉7种常见的食源性污染菌的抑菌效果,并通过倍比稀释法测定乙酸乙酯部分对其中3种细菌的最低抑菌浓度。结果表明:白刺果实乙酸乙酯部分、乙醇部分和氯仿部分对3种供试细菌均有抑菌作用,其中乙酸乙酯部分抑菌效果最好,且乙酸乙酯部分对3种细菌的抑制强弱顺序为:枯草芽孢杆菌〉大肠杆菌〉金黄色葡萄球菌

  17. Characterization of polymers by bubble inflation, Jens H. Christensen, Henrik K. Rasmussen, Erik M. Kjær and Carsten L. Lauridsen

    DEFF Research Database (Denmark)

    Rasmussen, Henrik Koblitz; Christensen, Jens H.; Kjær, Erik Michael

    1999-01-01

    In order to characterize materials using a simple and relative inexpensive method, the bubble inflation technique was modified. A polymer plate is clamped between a Teflon coated plate and a heated cylinder. By applying air through the heating plate the polymer membrane deforms into the cylinder...... is modelled using a finite element method in 3D Cartesian coordinates. The K-BKZ constitutive quation is used to model the non-linear properties of the material. Using linear viscoelastic properties from oscillative shear measurements and measurements of the bubble inflation, estimetion of the strain...

  18. Teatro y memoria: la recreación del mundo rural en Las manos, de José Ramón Fernández, Yolanda Pallín y Javier G. Yagüe

    Directory of Open Access Journals (Sweden)

    Vilches de Frutos, M. Francisca

    2002-06-01

    Full Text Available Current research on twentieth-century Spanish theater reveals a high number of historical plays, a tendency that has continued during the last five years. Some of the most significant writers currently writing for the stage are actively revising the recent past in their work. In this context, three playwrights stand out —Jose Ramon Fernandez, Yolanda Pallin and Javier G. Yague— thanks to the critical and commercial success of their Las manos (Hands, a play about young people who live in a rural area of Spain during the decade of the 1960s. The study of the play's themes and its reception bring to light the reasons behind this historical recreation and the favorable response accorded it by critics and audiences.El análisis de las representaciones escénicas llevadas a cabo en España durante el siglo XX permite apreciar la existencia de un elevado número de obras históricas. Esta tendencia ha tenido continuidad en el último lustro, donde algunos de los más destacados autores dramáticos no han dudado en iniciar una revisión del pasado reciente. En este contexto no debe sorprender el éxito crítico y comercial alcanzado por José Ramón Fernández, Yolanda Pallín y Javier G. Yagüe con Las manos, una obra protagonizada por jóvenes pertenecientes al ámbito rural español en la década de los sesenta. El estudio de sus claves temáticas y de su recepción permitirá explicar las razones para recrear este período histórico y las causas de su excelente acogida.

  19. 兴安圆柏嫩枝扦插过程中相关生理特征分析%Analysis of the physiological characteristics during the root formation of cuttings of Sabina davurica (Pall.) Ant.

    Institute of Scientific and Technical Information of China (English)

    郭英超; 李燕玲; 王子岚; 杜克久

    2012-01-01

      In order to discuss the cuttings rooting mechanism and to enhance the rooting rate of Sabina davurica (Pall.) Ant, the variations of the content of the water and nutrient components in twig cuttings were analyzed during the rooting process after treated with different endogenous hormones. The results show that the water and the soluble carbohydrate increased first and decreased later during the rooting process. The content of the soluble amylum presented a single peak curve, the soluble protein was a typical bi-modal curve. The plant hormones treatment promoted nutrient components transformation. All the changes were good for cuttings root-ing.%  为了提高兴安圆柏扦插生根率,探讨兴安圆柏的扦插生根机理,本试验采取不同激素处理兴安圆柏嫩枝插穗,分析嫩枝插条内水分及营养物质含量变化。结果表明,插穗生根过程中,水分、可溶性糖都是先降低后升高的过程,可溶性淀粉变化呈现升-降的单峰曲线,可溶性蛋白变化为升-降-升-降的双峰曲线。激素处理促进插穗内营养物质的转化,促进插穗生根。

  20. Determination of Amygdalin in Amygdalus pedunculatus Pall Products by Reversed-phase High Performance Liquid Chromatography%反相高效液相色谱法测定长柄扁桃仁产品中苦杏仁苷含量

    Institute of Scientific and Technical Information of China (English)

    寇凯; 许宁侠; 申烨华

    2013-01-01

    A method of reversed-phase high performance liquid chromatography(RP-HPLC) has been developed for the determination of amygdalin in amygdalus pedunculatus pall products.The sample of amygdalin in amygdalus pedunculatus pall was extracted in methanol.The separation was perfomed with a mobile phase of methanol and water and acetonitrile(2∶85∶ 13) and a detection wavelength of 220 nm.The average content of amygdalin in amygdalus pedunculatus pall detected by this method is 1.44 %.The linear range was from 50 to 300 μg/mL(r=0.9996).The limit of detection for amygdalin was 1.2 μg/mL,the average recovery was 98.9% (n=5).The method is accurate,reproducible and can be used for the quality control of amygdalin.%本文采用反相高效液相色谱建立了长柄扁桃仁系列产品中苦杏仁苷含量的测定方法.长柄扁桃仁系列产品中的苦杏仁苷经甲醇提取,以V(甲醇)∶V(水)∶V(乙腈)=2∶85∶13为流动相进行洗脱,在220 nm检测波长下,测得长柄扁桃仁中苦杏仁苷的平均质量分数为1.44%.方法线性范围为50~300 μg/mL,线性相关系数r=0.9996,检出限为1.2 μg/ml,平均回收率为98.97%(n=5).

  1. Model-Based Integration and Interpretation of Data

    DEFF Research Database (Denmark)

    Petersen, Johannes

    2004-01-01

    Data integration and interpretation plays a crucial role in supervisory control. The paper defines a set of generic inference steps for the data integration and interpretation process based on a three-layer model of system representations. The three-layer model is used to clarify the combination...... of constraint and object-centered representations of the work domain throwing new light on the basic principles underlying the data integration and interpretation process of Rasmussen's abstraction hierarchy as well as other model-based approaches combining constraint and object-centered representations. Based...

  2. 理化因子对芍药花色苷呈色的影响∗%Effect of Physical and Chemical Factors on Coloring of Anthocyanins Obtained from Herbaceous Peony (Paeonia lactiflora Pall.)

    Institute of Scientific and Technical Information of China (English)

    赵大球; 郝召君; 陶俊

    2015-01-01

    研究了理化因子对芍药花色苷溶液在体外呈色的影响。结果表明:芍药花色苷溶液在黑暗、室温(20℃)等条件下表现稳定;在自然光、紫外光、蓝光、白光、低温(4℃)、氧化剂(H2O2)、还原剂(Na2SO3)、Cu2+、Mn2+、Mg2+、Zn2+、Fe2+等条件下易于降解,颜色变淡;而红光、黄光、高温(40℃、60℃)、Na+对花色苷溶液具有一定的增色作用;不同pH对芍药花色苷溶液呈色影响并不一致。研究结果可为通过理化因子来调控芍药花色奠定基础。%The effect of physical and chemical factors on the coloring of anthocyanins in herbaceous peony (Paeonia lactiflora Pall.) was investigated in this paper. The results showed that darkness and room temperature (20℃) had no effect on the stability of anthocyanins. Furthermore, natural light, ultraviolet light, blue light, white light, low temperature (4℃), oxidant (H2O2), reductant (Na2 SO3 ) , Cu2+, Mn2+, Mg2+, Zn2+and Fe2+promoted the degradation of anthocyanins. In addition, red light, yellow light, high temperature (40℃ and 60℃) and Na+had color enhancing effect on an⁃thocyanins, and different pH value had different color effect on anthocyanins. These results would lay a foundation for regulating P. lactiflora flower color by physical and chemical factors.

  3. Ib & Jørgen Rasmussen Arkitekter

    DEFF Research Database (Denmark)

    Lund, Nils-Ole

    2007-01-01

    1960’erne og 1970’erne var der stort set ikke den arkitektkonkurrence, hvor tvillingerne Ib & Jørgen ikke fik en placering eller et indkøb, og dette sprudlende og talentfulde arkitektpar har nu fået den portrætbog, de så længe har fortjent. Henved 100 énfamiliehuse og markante hovedværker som Sol...

  4. Medierne og Lars Løkke Rasmussen

    DEFF Research Database (Denmark)

    Dindler, Camilla

    2014-01-01

    Hvad gik galt med nyhedsmedierne i de forgangne ugers Løkke-sag? Kritikerne mener, at pressens håndtering blev et eksempel på uprofessionel omgang med anonyme kilder, ensidighed og uholdbare forudsigelser. Hvordan kunne dette ske?...

  5. Rasmussen kom i klemme med firmaets kreditkort

    DEFF Research Database (Denmark)

    Langsted, Lars Bo

    2004-01-01

    Højesteret har netop stemplet et aftalevilkår i kortindehaverreglerne for Eurocard som værende i strid med redelig handlemåde. Samtidig har afgørelsen ført til en klart forbedret retsstilling for ansatte, der anvender firmakort....

  6. Guiding young adults at risk

    DEFF Research Database (Denmark)

    Andreasen, Karen Egedal; Rasmussen, Palle Damkjær; Ydesen, Christian

    2016-01-01

    Karen Egedal Andreasen, Palle Rasmussen and Christian Ydesen question in their article, how to guide youth in danger of being marginalised or excluded from society in general and the labour market in particular. They analyse the guidance dimension in the youth in development project as described ...

  7. Palle Qvist's Blog about Digital Teaching

    DEFF Research Database (Denmark)

    Qvist, Palle

    2010-01-01

    Blog created to support the first pedagogical day about e-learning arranged by the official AAU – “Pedagogical open day in Aalborg 17th of March 2010″. New articles added continuosly......Blog created to support the first pedagogical day about e-learning arranged by the official AAU – “Pedagogical open day in Aalborg 17th of March 2010″. New articles added continuosly...

  8. Palle Qvist's Blog about Digital Teaching

    DEFF Research Database (Denmark)

    Qvist, Palle

    2010-01-01

    Blog created to support the first pedagogical day about e-learning arranged by the official AAU – “Pedagogical open day in Aalborg 17th of March 2010″. New articles added continuosly......Blog created to support the first pedagogical day about e-learning arranged by the official AAU – “Pedagogical open day in Aalborg 17th of March 2010″. New articles added continuosly...

  9. A Control Technology for Plantlets Fast Growing of Rhododendron chrysanthum Pall.in Changbai Mountain%长白山牛皮杜鹃种苗速生调控技术

    Institute of Scientific and Technical Information of China (English)

    顾地周; 沈红梅; 闫中雪; 徐鹏佳; 袁浩; 杨丽娟; 王秋爽; 张学士

    2014-01-01

    We used the plantlets of Rhododendron chrysanthum Pall.to study the main factors with different levels by repeated experiments with multi factorial for establishing a control system of plantlets fast growing of R.chrysanthum.The the main factors with levels for plantlets fast growing of R.chrysanthum are under the light hours of 13 h· d-1 , the interval time of topdressing nutrient solution of 21-22 days, the light intensity of 700-800 lx and the temperature of 26℃.The longitudi-nal growth height and transverse diameter of plantlets of R.chrysanthum were 17.6 cm and 6.0 mm in 25 d, and 26.0 cm and 7.4 mm in 50 d, respectively.The growing height and stem diameter of contrast plant were only 8.8 cm和2.0 mm in 25 d, and 10.2 cm and 2.9 mm in 50 d, respectively.We got the optimization for plantlets fast growing of R.chrysanthum.%本研究以牛皮杜鹃组培苗为供试植物,通过多因子交叉重复试验对影响牛皮杜鹃组培苗快速生长的各主要因素及其水平的作用进行了探讨,旨在探索并建立一种牛皮杜鹃种苗快速生长的调控方法。结果表明:最适合牛皮杜鹃组培苗快速生长的主要因素及其水平是光照时间为13 h· d-1、营养液追施间隔时间为21~22 d、光照强度为700~800 lx和温度为26℃。经过25 d的调控处理,牛皮杜鹃组培苗纵向生长高度和横向直径分别达到17.6 cm和6.0 mm,对照组仅分别达到8.8 cm和2.0 mm;50 d后纵向生长高度和横向直径分别达到26.0 cm和7.4 mm,而对照组仅分别达到10.2 cm和2.9 mm。初步得到牛皮杜鹃种苗速生的优化组合,该组合将有利于牛皮杜鹃种苗的快速生长。

  10. Rasmussen ei näe Taanile euroliidus erandeid / Toomas Hendrik Ilves, Anders Fogh Rasmussen

    Index Scriptorium Estoniae

    Ilves, Toomas Hendrik, 1953-

    2003-01-01

    Eesti endise välisministri Toomas Hendrik Ilvese ja Taani peaministri Anders Fogh Rasmusseni televestlus Taani aktiivsest välispoliitikast, NATO laienemisest ja arengust, Taani kuulumisest EL-i, Euroopa riikide koostööst, euro kasutuselevõtust Taanis

  11. The development of human behavior analysis techniques - A study on knowledge representation methods for operator cognitive model

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jung Woon; Park, Young Tack [Soongsil University, Seoul (Korea, Republic of)

    1996-07-01

    The main objective of this project is modeling of human operator in a main control room of Nuclear Power Plant. For this purpose, we carried out research on knowledge representation and inference method based on Rasmussen`s decision ladder structure. And we have developed SACOM(Simulation= Analyzer with a Cognitive Operator Model) using G2 shell on Sun workstations. SACOM consists of Operator Model, Interaction Analyzer, Situation Generator. Cognitive model aims to build a more detailed model of human operators in an effective way. SACOM is designed to model knowledge-based behavior of human operators more easily. The followings are main research topics carried out this year. First, in order to model knowledge-based behavior of human operators, more detailed scenarios are constructed. And, knowledge representation and inference methods are developed to support the scenarios. Second, meta knowledge structures are studied to support human operators 4 types of diagnoses. This work includes a study on meta and scheduler knowledge structures for generate-and-test, topographic, decision tree and case-based approaches. Third, domain knowledge structure are improved to support meta knowledge. Especially, domain knowledge structures are developed to model topographic diagnosis model. Fourth, more applicable interaction analyzer and situation generator are designed and implemented. The new version is implemented in G2 on Sun workstations. 35 refs., 49 figs. (author)

  12. Visual behaviour analysis and driver cognitive model

    Energy Technology Data Exchange (ETDEWEB)

    Baujon, J.; Basset, M.; Gissinger, G.L. [Mulhouse Univ., (France). MIPS/MIAM Lab.

    2001-07-01

    Recent studies on driver behaviour have shown that perception - mainly visual but also proprioceptive perception - plays a key role in the ''driver-vehicle-road'' system and so considerably affects the driver's decision making. Within the framework of the behaviour analysis and studies low-cost system (BASIL), this paper presents a correlative, qualitative and quantitative study, comparing the information given by visual perception and by the trajectory followed. This information will help to obtain a cognitive model of the Rasmussen type according to different driver classes. Many experiments in real driving situations have been carried out for different driver classes and for a given trajectory profile, using a test vehicle and innovative, specially designed, real-time tools, such as the vision system or the positioning module. (orig.)

  13. 水分胁迫下 AM 真菌和根瘤菌对沙打旺生长及养分吸收的影响%Inoculation of arbuscular mycorrhizal fungi and Rhizobium on the growth and nutrition uptake of Astragalus adsurgens Pall .under water stress

    Institute of Scientific and Technical Information of China (English)

    吴福勇; 武玉坤; 毕银丽; 齐礼帅; 李丽娟

    2013-01-01

      利用温室盆栽试验研究水分胁迫下接种丛枝菌根(Arbuscular mycorrhizal ,AM)真菌和根瘤菌(Rhizobium meliloti)对沙打旺(Astragalus adsurgens Pall .)生长和养分吸收的影响。在土壤相对含水量65%和35%条件下,分别设不接种(对照)、单接根瘤菌、单接摩西球囊霉(Glomus mosseae)和双接根瘤菌与摩西球囊霉等4个处理。结果发现:干旱胁迫显著抑制沙打旺AM真菌侵染率(P<0.05),而接种根瘤菌在两种水分条件下均显著促进摩西球囊霉对沙打旺根系的侵染(P<0.05)。接种AM真菌不仅显著提高沙打旺对P的吸收(P<0.05),而且明显促进根瘤的生长。无论是在干旱条件下或是在正常供水条件下,双接根瘤菌与摩西球囊霉处理对沙打旺生长及养分吸收的效应显著高于单接菌处理,植株地上部、地下部生物量以及N、P、K等吸收量均为最大。结果表明:AM真菌与根瘤菌双接种技术在干旱、半干旱区受损生态系统的植被恢复中具有一定的应用潜力。%A pot trial was conducted in greenhouse to investigate the effects of arbuscular mycorrhizal (AM ,Glomus mosseae) and Rhizobium on the growth and nutrition uptake of Astragalus adsurgens Pall .under water stress .There were four treatments ,including control (no inoculation) ,inoculation of Rhizobium ,inoculation of G .mosseae and dual inoc-ulation of Rhizobium and G .mosseae ,either in 35% or 65% of soil relative water content .The results showed that wa-ter stress significantly (P<0 .05) decreased the mycorrhizal infection of A .adsurgens ,while the inoculation of Rhizobi-um significantly ( P<0 .05) increased the infection regardless of water condition .The inoculation of G .mosseae not only significantly increased P uptake of A .adsurgens ,but also increased the growth of root nodules .Regardless of water con-dition ,the dual inoculation of G .mosseae and Rhizobium

  14. Løkke lykkes

    DEFF Research Database (Denmark)

    Bengtsson, Mette

    2011-01-01

    Næsten alle er enige: Statsministerens nytårstale var stærk. Lars Løkke Rasmussen er ikke en mand, der normalt høster ros som den store taler, men hans nytårstale lykkes retorisk. Talen giver mindelser om Reagans slogans, Voltaires ordsprog, Krønikens Palle From – og så har den suspense. Men...

  15. α-Glucosidase Inhibitory Activitives of S.xanthoxylon Bunge ,N.tangutorum Bobr and N.sibirica Pall, grown in Neimenggu from Zygophyllaceae%内蒙古产白刺、小果白刺和霸王α-葡萄糖苷酶抑制活性

    Institute of Scientific and Technical Information of China (English)

    常星; 康文艺

    2012-01-01

    首次利用体外α-葡萄糖苷酶抑制模型对内蒙古产3种蒺藜科植物的9个提取物进行活性评价,并与阳性对照Acarbose比较,发现3种植物均有抑制α-葡萄糖苷酶活性.其中白刺石油醚提取物对α-葡萄糖苷酶的抑制活性(IC50 =81.80 mg/L)最高,其余依次为小果白刺乙酸乙酯提取物(IC50=610.29 mg/L),霸王石油醚(IC50=627.22mg/L)和乙酸乙酯提取物(IC50 =838.40 mg/L),它们的抑制活性远大于阳性对照Acarbose( IC50=1103.01 mg/L).结果发现,不同植物不同溶剂提取物的α-葡萄糖苷酶抑制活性不同.同一植物不同溶剂提取物相比较,甲醇提取物的α-葡萄糖苷酶抑制活性不及乙酸乙酯和石油醚提取物.%The a-glucosidase inhibitory activities of nine extracts from three species of Zygophyllaceae in Neimenggu were evaluated in vitro by 96-microplate-based method for the first time. All these three species showed a-glucosidase inhibitory activities compared with the positive control " acarbose ". Among these nine extracts, petroleum ether extract of Nitraria tangutorum Bobr. Had the highest inhibitory activity (IC50 =81.80 mg/L) .followed by the ethyl acetate extract of N. Sibirica Pall( IC50 = 610.29 mg/L) ,the petroleum ether extract (IC50, = 627. 22 mg/L) and ethyl acetate extract (IC50 =838.40 mg/L) of Sarcozygium xanthoxylon Bunge,all of which are much higher than that of acarbose (IC50= 1103.01 mg/mL). Different extracts of different plants showed different inhibitory activies, while the inhibitory activity of different extracts from the same plant varied a lot. The methanolic extract had lower inhibitory activity than that of ethyl acetate extract and petroleum ether extract.

  16. An Exploration into the Uses of Agent-Based Modeling to Improve Quality of Healthcare

    Science.gov (United States)

    Kanagarajah, Ashok Kay; Lindsay, Peter; Miller, Anne; Parker, David

    Healthcare is a complex adaptive system. This paper discusses, healthcare in the context of complex systems architecture and an agent based modeling framework. The paper demonstrates complications of healthcare system improvement and it's impact on patient safety, economics and workloads. Further an application of safety dynamics model proposed by Cook and Rasmussen4 is explored using a hypothetical simulation of an emergency department. By means of simulation, this paper demonstrates the nonlinear behaviors of a health service unit and its complexities; and how the safety dynamic model may be used to evaluate various aspects of healthcare. Further work is required to apply this concept in a 'real life environment' and its consequence to societal, organizational and operational levels of healthcare.

  17. Lõpp naiste ja meeste palgavahele / Poul Nyrup Rasmussen, Marianne Mikko

    Index Scriptorium Estoniae

    Rasmussen, Poul Nyrup

    2007-01-01

    Euroopa sotsiaaldemokraadid alustavad võitlust meeste ja naiste vahel püsiva palgaerinevusega. Euroopa Sotsiaaldemokraatliku Partei esimehe ja Euroopa Sotsiaaldemokraatliku Partei naisühenduse juhatuse liikme sõnul juhitakse tähelepanu ebaõiglusele, andes 22. veebruarile erilise tähenduse. See on päev, kui naissoost töötajad alustavad tõsist palgateemalist dialoogi oma tööandjate ja kolleegidega

  18. The 3D Lagrangian Integral Method. Henrik Koblitz Rasmussen

    DEFF Research Database (Denmark)

    Rasmussen, Henrik Koblitz

    2003-01-01

    . This are processes such as thermo-forming, gas-assisted injection moulding and all kind of simultaneous multi-component polymer processing operations. Though, in all polymer processing operations free surfaces (or interfaces) are present and the dynamic of these surfaces are of interest. In the "3D Lagrangian...

  19. Critical Exchange: Avoiding Schooling Taboos--A Reply to Rasmussen

    Science.gov (United States)

    Stern, Julian

    2017-01-01

    This paper is a reply to Mary L. Rasumussen's paper, "Critical Exchange: Religion and Schooling: What Should Their Relationship Be?" In this paper, Julian Stern makes three claims: (1) the need for a messy conversation; (2) the need to include "whole" people in schools; and (3) the need to consider existentially significant…

  20. Rasmussen reassures on NATO security guarantees / Rokas M. Tracevskis

    Index Scriptorium Estoniae

    Tracevskis, Rokas M.

    2009-01-01

    NATO peasekretäri Anders Fogh Rasmusseni Läti visiidist, mille käigus külastas ta Šiauliai lähedal asuvat Zokniai õhubaasi ja kohtus Leedu presidendi Dalia Grybauskaite, peaminister Andrius Kubiliuse ja välisminister Vygaudas Usackasega

  1. Modified of an Accepted Animal Model of Osteomyelitis to Simulate and Evaluate Treatment of War Extremity Wounds. Addendum

    Science.gov (United States)

    2012-07-01

    irrigation improves the ability to remove bacteria. J Bone Joint Surg Am. 2007;89:1723–1726. 173. Leininger BE, Rasmussen TE, Smith DL, Jenkins DH...22. 136. Leininger BE, Rasmussen TE, Smith DL, Jenkins DH, Coppola C. Experience with wound VAC and delayed primary closure of contam- inated soft

  2. How Repeated Time To Event (RTTE) modelling of opioid requests after surgery may improve future post-operative pain management

    DEFF Research Database (Denmark)

    Juul, Rasmus Vestergaard; Rasmussen, Sten; Kreilgaard, Mads

    Title: How Repeated Time To Event (RTTE) modelling of opioid requests after surgery may improve future post-operative pain management Author: Rasmus Vestergaard Juul (1) Sten Rasmussen (2) Mads Kreilgaard (1) Ulrika S. H. Simonsson (3) Lona Louring Christrup (1) Trine Meldgaard Lund (1) Institution...... to Event (RTTE) modelling2 approach of repeated opioid request in order to increase the understanding of pain breakthrough patterns in severe surgeries and improve patients’ pain management. Methods: 68 patients (F:45,M:23, Age:76±15) were included from a population receiving surgery after hip fracture...... of surgery specific, drug concentration related, population specific and/or time-varying covariates of opioid requests and pain events. Conclusions: A framework has been developed based on RTTE modelling that may help improve future pain management by 1) Identification of surgery specific patterns in pain...

  3. Pall oma väravasse? / Heidi Pruuli

    Index Scriptorium Estoniae

    Pruuli, Heidi, 1954-

    2008-01-01

    ETV peatoimetaja arvates näitavad nii Riigikogu kui ka valitsus rahvusringhäälingu vastu üles ükskõiksust ja tõrjuvust ning ta viitab litsentsimaksu kaotamisele, samal ajal kui rahvusringhäälingu tänavusi eelarvetoetusi vähendati 37 mln. krooni võrra

  4. Sotsiaaluuringud aitavad juhtida perepoliitikat / Kati Karelson, Katre Pall

    Index Scriptorium Estoniae

    Karelson, Kati

    2003-01-01

    Riiklikust perepoliitikast, selle tulemuste analüüs ja võrdlus teistes Euroopa riikides rakendatud institutsionaalsete meetmetega. Artikkel põhineb Euroopa Komisjoni 5. raamprogrammi projektina rahastatud ja aastail 2000-2003 korraldatud uuringu IPROSEC tulemustel. Skeemid. Tabel

  5. Accountability and transparency of financial sector supervision / Pall Gunnar Palsson

    Index Scriptorium Estoniae

    Palsson, Pall Gunnar

    2001-01-01

    Finantsjärelvalve üheks oluliseks tingimuseks on läbipaistvus. Rahvusvahelise Valuutafondi poolt vastu võetud raha- ja rahanduspoliitika heade tavade koodeksist. Ülevaade Islandi finantsinspektsiooni töökorraldusest

  6. Shoot multiplication and plant regeneration in Caragana fruticosa (Pall.) Besser

    Institute of Scientific and Technical Information of China (English)

    ZHAI Xiao-jie; YANG Ling; SHEN Hai-long

    2011-01-01

    Different nutrient media can affectin vitro culturing protocols,and experimentation under varied growth conditions is valuable in plants where in vitro methods are in preliminary stages.We carried out the first in vitro propagation studies for the endangered species Caragana fruticosa (Fabaceae).We evaluated various nutrient media for their inpact on shoot elongation and axillary bud proliferation using different concentrations of 6-benzylaminopurine (BA) and α-naphthaleneacetic acid (NAA).Shoot elongation was evaluated based on adventitious shoot primary culture and subculture regeneration from Caragana seedlings.Our goal was to improve both micropropagation and regeneration in C.fruticosa.MS nutrient media was superior to 1/2MS macronutrients,DKW,QL,and WPM for shoot elongation and axillary shoot proliferation.Shoots grown on 1/2MS and WPM exhibited some chlorosis,and shoots on QL produced larger leavers than plants growing on normal medium.The shoot proliferation coefficient on MS media supplemented with 2.22 μM BA and 0.44 μM BA + 2.69 μM NAA was significantly higher than that with other treatments in the primary culture.Shoots on 2.22 μM BA showed a higher proliferation coefficient (3.17) than others in the subculture.Shoots were rooted on 1/2MS medium with the addition of different concentrations of NAA.The optimal concentration for rooting was 0.27 μM NAA (74%).Roots exhibited many stout and long root hairs.Survivl of established plantlets was 82% at 30 days after transfer to soil.Plants established in the green house showed normal growth and displayed no apparent morphological differences compared to stock plants.

  7. Sotsiaaluuringud aitavad juhtida perepoliitikat / Kati Karelson, Katre Pall

    Index Scriptorium Estoniae

    Karelson, Kati

    2003-01-01

    Riiklikust perepoliitikast, selle tulemuste analüüs ja võrdlus teistes Euroopa riikides rakendatud institutsionaalsete meetmetega. Artikkel põhineb Euroopa Komisjoni 5. raamprogrammi projektina rahastatud ja aastail 2000-2003 korraldatud uuringu IPROSEC tulemustel. Skeemid. Tabel

  8. Accountability and transparency of financial sector supervision / Pall Gunnar Palsson

    Index Scriptorium Estoniae

    Palsson, Pall Gunnar

    2001-01-01

    Finantsjärelvalve üheks oluliseks tingimuseks on läbipaistvus. Rahvusvahelise Valuutafondi poolt vastu võetud raha- ja rahanduspoliitika heade tavade koodeksist. Ülevaade Islandi finantsinspektsiooni töökorraldusest

  9. Influence of magnetospheric inputs definition on modeling of ionospheric storms

    Science.gov (United States)

    Tashchilin, A. V.; Romanova, E. B.; Kurkin, V. I.

    Usually for numerical modeling of ionospheric storms corresponding empirical models specify parameters of neutral atmosphere and magnetosphere. Statistical kind of these models renders them impractical for simulation of the individual storm. Therefore one has to correct the empirical models using various additional speculations. The influence of magnetospheric inputs such as distributions of electric potential, number and energy fluxes of the precipitating electrons on the results of the ionospheric storm simulations has been investigated in this work. With this aim for the strong geomagnetic storm on September 25, 1998 hour global distributions of those magnetospheric inputs from 20 to 27 September were calculated by the magnetogram inversion technique (MIT). Then with the help of 3-D ionospheric model two variants of ionospheric response to this magnetic storm were simulated using MIT data and empirical models of the electric fields (Sojka et al., 1986) and electron precipitations (Hardy et al., 1985). The comparison of the received results showed that for high-latitude and subauroral stations the daily variations of electron density calculated with MIT data are more close to observations than those of empirical models. In addition using of the MIT data allows revealing some peculiarities in the daily variations of electron density during strong geomagnetic storm. References Sojka J.J., Rasmussen C.E., Schunk R.W. J.Geophys.Res., 1986, N10, p.11281. Hardy D.A., Gussenhoven M.S., Holeman E.A. J.Geophys.Res., 1985, N5, p.4229.

  10. ЦВЕТЕНИЕ И ПЛОДОНОШЕНИЕ РАСТЕНИЙ GENTIANA SCABRA BUNGE И G. TRIFLORA PALL. НА ЮГЕ ПРИМОРСКОГО КРАЯ РОССИИ

    OpenAIRE

    Янь, Чжиюань; Сунь, Янь; Царенко, Н.

    2009-01-01

    Изложены результаты наблюдений за цветением и плодоношением двух видов горечавок (Gentiana scabra Bunge и G. triflora Pall.) на юге Приморского края. Установлено, что основными насекомыми-опылителями являются шмели. Выявлены оптимальные сроки для проведения работ по гибридизации. Отмечено, что при выращивании растений в культуре не нарушаются сроки прохождения основных фенологических фаз....

  11. Logarithmic Minimal Models with Robin Boundary Conditions

    CERN Document Server

    Bourgine, Jean-Emile; Tartaglia, Elena

    2016-01-01

    We consider general logarithmic minimal models ${\\cal LM}(p,p')$, with $p,p'$ coprime, on a strip of $N$ columns with the $(r,s)$ Robin boundary conditions introduced by Pearce, Rasmussen and Tipunin. The associated conformal boundary conditions are labelled by the Kac labels $r\\in{\\Bbb Z}$ and $s\\in{\\Bbb N}$. The Robin vacuum boundary condition, labelled by $(r,s\\!-\\!\\frac{1}{2})=(0,\\mbox{$\\textstyle \\frac{1}{2}$})$, is given as a linear combination of Neumann and Dirichlet boundary conditions. The general $(r,s)$ Robin boundary conditions are constructed, using fusion, by acting on the Robin vacuum boundary with an $(r,s)$-type seam consisting of an $r$-type seam of width $w$ columns and an $s$-type seam of width $d=s-1$ columns. The $r$-type seam admits an arbitrary boundary field which we fix to the special value $\\xi=-\\tfrac{\\lambda}{2}$ where $\\lambda=\\frac{(p'-p)\\pi}{2p'}$ is the crossing parameter. The $s$-type boundary introduces $d$ defects into the bulk. We consider the associated quantum Hamiltoni...

  12. Reperfusion Strategies in the Management of Extremity Vascular Injury with Ischaemia

    Science.gov (United States)

    2012-01-01

    Spencer JR, Rasmussen TE. A large animal survival model (Sus scrofa ) of extremity ischemia/reperfusion and neuromuscular outcomes assessment: a pilot...on neuromuscular recovery in a porcine (Sus scrofa ) survival model of extremity vascular injury. J Vasc Surg 2011; 53: 165–173. 32 Rasmussen TE

  13. Fast Simulation of Membrane Filtration by Combining Particle Retention Mechanisms and Network Models

    Science.gov (United States)

    Krupp, Armin; Griffiths, Ian; Please, Colin

    2016-11-01

    Porous membranes are used for their particle retention capabilities in a wide range of industrial filtration processes. The underlying mechanisms for particle retention are complex and often change during the filtration process, making it hard to predict the change in permeability of the membrane during the process. Recently, stochastic network models have been shown to predict the change in permeability based on retention mechanisms, but remain computationally intensive. We show that the averaged behaviour of such a stochastic network model can efficiently be computed using a simple partial differential equation. Moreover, we also show that the geometric structure of the underlying membrane and particle-size distribution can be represented in our model, making it suitable for modelling particle retention in interconnected membranes as well. We conclude by demonstrating the particular application to microfluidic filtration, where the model can be used to efficiently compute a probability density for flux measurements based on the geometry of the pores and particles. A. U. K. is grateful for funding from Pall Corporation and the Mathematical Institute, University of Oxford. I.M.G. gratefully acknowledges support from the Royal Society through a University Research Fellowship.

  14. Zonal rate model for axial and radial flow membrane chromatography, part II: model-based scale-up.

    Science.gov (United States)

    Ghosh, Pranay; Lin, Min; Vogel, Jens H; Choy, Derek; Haynes, Charles; von Lieres, Eric

    2014-08-01

    Membrane chromatography (MC) systems are finding increasing use in downstream processing trains for therapeutic proteins due to the unique mass-transfer characteristics they provide. As a result, there is increased need for model-based methods to scale-up MC units using data collected on a scaled-down unit. Here, a strategy is presented for MC unit scale-up using the zonal rate model (ZRM). The ZRM partitions an MC unit into virtual flow zones to account for deviations from ideal plug-flow behavior. To permit scale-up, it is first configured for the specific device geometry and flow profiles within the scaled-down unit so as to achieve decoupling of flow and binding related non-idealities. The ZRM is then configured for the preparative-scale unit, which typically utilizes markedly different flow manifolds and membrane architecture. Breakthrough is first analyzed in both units under non-binding conditions using an inexpensive tracer to independently determine unit geometry related parameters of the ZRM. Binding related parameters are then determined from breakthrough data on the scaled-down MC capsule to minimize sample requirements. Model-based scale-up may then be performed to predict band broadening and breakthrough curves on the preparative-scale unit. Here, the approach is shown to be valid when the Pall XT140 and XT5 capsules serve as the preparative and scaled-down units, respectively. In this case, scale-up is facilitated by our finding that the distribution of linear velocities through the membrane in the XT140 capsule is independent of the feed flow rate and the type of protein transmitted. Introduction of this finding into the ZRM permits quantitative predictions of breakthrough over a range of industrially relevant operating conditions. © 2014 The Authors Biotechnology and Bioengineering Published by Wiley Periodicals, Inc.

  15. ЧИСЛО ХРОМОСОМ И ГИБРИДИЗАЦИЯ ГОРЕЧАВКИ ШЕРОХОВАТОЙ (GENTIANA SCABRA BUNGE) И ГОРЕЧАВКИ ТРЕХЦВЕТКОВОЙ (GENTIANA TRIFLORA PALL.) НА ЮГЕ ПРИМОРСКОГО КРАЯ РОССИИ

    OpenAIRE

    ЛИЦЗЕ ЮЙ; СИНЬСИНЬ ЛИ; ЯНЬ СУНЬ

    2016-01-01

    Изучены числа хромосом и проведены эксперименты по искусственной гибридизации лекарственных растений Gentiana scabra Bunge и G. triflora Pall., широко используемых в Китае. На обширном материале показано, что оба вида характеризуются одним и тем же числом хромосом (2n=26), что может способ-ствовать успешной гибридизации этих видов. Для G. triflora число хромосом установлено впервые. В условиях культуры были получены гибриды этих видов и проанализирована их фертильность. Установлено, что в вар...

  16. Cognitive engineering models in space systems

    Science.gov (United States)

    Mitchell, Christine M.

    1993-01-01

    NASA space systems, including mission operations on the ground and in space, are complex, dynamic, predominantly automated systems in which the human operator is a supervisory controller. Models of cognitive functions in complex systems are needed to describe human performance and form the theoretical basis of operator workstation design, including displays, controls, and decision aids. Currently, there several candidate modeling methodologies. They include the Rasmussen abstraction/aggregation hierarchy and decision ladder, the goal-means network, the problem behavior graph, and the operator function model. The research conducted under the sponsorship of this grant focuses on the extension of the theoretical structure of the operator function model and its application to NASA Johnson mission operations and space station applications. The initial portion of this research consists of two parts. The first is a series of technical exchanges between NASA Johnson and Georgia Tech researchers. The purpose is to identify candidate applications for the current operator function model; prospects include mission operations and the Data Management System Testbed. The second portion will address extensions of the operator function model to tailor it to the specific needs of Johnson applications. At this point, we have accomplished two things. During a series of conversations with JSC researchers, we have defined the technical goal of the research supported by this grant to be the structural definition of the operator function model and its computer implementation, OFMspert. Both the OFM and OFMspert have matured to the point that they require infrastructure to facilitate use by researchers not involved in the evolution of the tools. The second accomplishment this year was the identification of the Payload Deployment and Retrieval System (PDRS) as a candidate system for the case study. In conjunction with government and contractor personnel in the Human-Computer Interaction Lab

  17. Rheological behaviour of polyethylene with peroxide crosslinking agent. Ismaeil Ghasemi, Peter Szabo and Henrik Koblitz Rasmussen

    DEFF Research Database (Denmark)

    Rasmussen, Henrik K.; Ghasemi, Ismaeil; Szabo, Peter

    2003-01-01

    due to a peroxide cross-linking reaction of low-density polyethylene (LDPE) was tracked by a combination of creep tests and differential scanning calorimetry (DSC) tests in isothermal conditions. The peroxide was di-cumyl peroxide and its concentration was 2 wt%. The experiments were carried out...

  18. Reply to Ira Rabin's Comment on our paper Rasmussen et al. (2012)

    DEFF Research Database (Denmark)

    Rasmussen, K. L.; Tenorio, Anna Lluveras; Bonaduce, Ilaria;

    2014-01-01

    In the Comment by Dr. I. Rabin from Bundesanstalt für Materialforschung und -prüfung in Berlin are stated many conjectures and apparent guesses contradicting several of our interpretations. Most of Rabin's ‘guesses’ and interpretations are unwarranted. Below we rebut some of the misinterpretation...

  19. Espen Rasmussen: need on pildid, mida soovite, et poleks kunagi pildistatud / intervjueerinud Hanne Mathisen

    Index Scriptorium Estoniae

    Rasmussen, Espen, 1976-

    2011-01-01

    Intervjuu norra fotograafiga, kelle 33 fotot saab 13.-23. juunini näha Tallinnas Rotermanni kvartalis, juunis veel Valgas ja Narvas. Fotod on pildistatud viimase seitsme aasta jooksul pagulaslaagrites Colombias, Kongo DV-s, Afganistanis, Jeemenis, Gruusias ja Süürias. Näitus toimub rahvusvahelise migratsiooniorganisatsiooni projekti "Avaliku teadlikkuse tõstmine migratsiooni- ja varjupaigatemaatikal Eestis: Pagulased?, Kes?, Miks? (PARE)" raames

  20. Reply to Ira Rabin's Comment on our paper Rasmussen et al. (2012)

    DEFF Research Database (Denmark)

    Rasmussen, K. L.; Tenorio, Anna Lluveras; Bonaduce, Ilaria

    2014-01-01

    In the Comment by Dr. I. Rabin from Bundesanstalt für Materialforschung und -prüfung in Berlin are stated many conjectures and apparent guesses contradicting several of our interpretations. Most of Rabin's ‘guesses’ and interpretations are unwarranted. Below we rebut some of the misinterpretations...

  1. Reply to Ira Rabin’s Comment on our paper Rasmussen et al.

    NARCIS (Netherlands)

    Rasmussen, Kaare Lund; Tenorio, Anna Lluveras; Bonaduce, Ilaria; Colombini, Maria Perla; Birolo, Leila; Galano, Eugenio; Amoresano, Angela; Doudna, Greg; Bond, Andrew D.; Palleschi, Vincenzo; Lorenzetti, Giulia; Legnaioli, Stefano; van der Plicht, Johannes; Gunneweg, Jan

    2012-01-01

    In the Comment by Dr. I. Rabin from Bundesanstalt für Materialforschung und -prüfung in Berlin are stated many conjectures and apparent guesses contradicting several of our interpretations. Most of Rabin’s ‘guesses’ and interpretations are unwarranted. Below we rebut some of the misinterpretations

  2. Rheological behaviour of polyethylene with peroxide crosslinking agent. Ismaeil Ghasemi, Peter Szabo and Henrik Koblitz Rasmussen

    DEFF Research Database (Denmark)

    Rasmussen, Henrik K.; Ghasemi, Ismaeil; Szabo, Peter

    2003-01-01

    due to a peroxide cross-linking reaction of low-density polyethylene (LDPE) was tracked by a combination of creep tests and differential scanning calorimetry (DSC) tests in isothermal conditions. The peroxide was di-cumyl peroxide and its concentration was 2 wt%. The experiments were carried out...

  3. Reply to Ira Rabin’s Comment on our paper Rasmussen et al.

    NARCIS (Netherlands)

    Rasmussen, Kaare Lund; Tenorio, Anna Lluveras; Bonaduce, Ilaria; Colombini, Maria Perla; Birolo, Leila; Galano, Eugenio; Amoresano, Angela; Doudna, Greg; Bond, Andrew D.; Palleschi, Vincenzo; Lorenzetti, Giulia; Legnaioli, Stefano; van der Plicht, Johannes; Gunneweg, Jan

    2014-01-01

    In the Comment by Dr. I. Rabin from Bundesanstalt für Materialforschung und -prüfung in Berlin are stated many conjectures and apparent guesses contradicting several of our interpretations. Most of Rabin’s ‘guesses’ and interpretations are unwarranted. Below we rebut some of the misinterpretations u

  4. Rasmussen's syndrome:a report of 1 case%Rasmussen综合征一例报道

    Institute of Scientific and Technical Information of China (English)

    李继平; 陶蔚; 张宇清; 张国君; 李勇杰

    2011-01-01

    @@ 患儿,男,4岁3个月时出现发作性愣神,数秒可缓解.1个月后,开始频繁的右侧肢体单纯部分性运动性发作,100~200次/d.6个月后,发展成简单部分发作持续状态(epilepsia partialis continua,EPC),予德巴金和水合氯醛治疗,发作减轻至约100次/d.10个月后,患儿因再次出现EPC而就诊于宣武医院.

  5. Exposiciones en la Biblioteca Luis Ángel Arango: Irene Balas y Henry Rasmussen

    Directory of Open Access Journals (Sweden)

    Luis Borobio

    1960-06-01

    Full Text Available La lluvia que cae sobre un estanque rompe los reflejos multicolores en infinitas formas caprichosas, cambiantes y siempre inéditas, que desaparecen y se renuevan sin que quizá las hayamos advertido. El sol ensaya en las nubes -espontáneamente modeladas por el viento- irisaciones insospechadas que nunca se repiten.

  6. Models

    DEFF Research Database (Denmark)

    Juel-Christiansen, Carsten

    2005-01-01

    Artiklen fremhæver den visuelle rotation - billeder, tegninger, modeller, værker - som det privilligerede medium i kommunikationen af ideer imellem skabende arkitekter......Artiklen fremhæver den visuelle rotation - billeder, tegninger, modeller, værker - som det privilligerede medium i kommunikationen af ideer imellem skabende arkitekter...

  7. The Electronic Behavior of Zinc-Finger Protein Binding Sites in the Context of the DNA Extended Ladder Model

    Science.gov (United States)

    Oiwa, Nestor; Cordeiro, Claudette; Heermann, Dieter

    2016-05-01

    Instead of ATCG letter alignments, typically used in bioinformatics, we propose a new alignment method using the probability distribution function of the bottom of the occupied molecular orbital (BOMO), highest occupied molecular orbital (HOMO) and lowest unoccupied orbital (LUMO). We apply the technique to transcription factors with Cys2His2 zinc fingers. These transcription factors search for binding sites, probing for the electronic patterns at the minor and major DNA groves. The eukaryotic Cys2His2 zinc finger proteins bind to DNA ubiquitously at highly conserved domains. They are responsible for gene regulation and the spatial organization of DNA. To study and understand these zinc finger DNA-protein interactions, we use the extended ladder in the DNA model proposed by Zhu, Rasmussen, Balatsky & Bishop (2007) te{Zhu-2007}. Considering one single spinless electron in each nucleotide π-orbital along a double DNA chain (dDNA), we find a typical pattern for the bottom of BOMO, HOMO and LUMO along the binding sites. We specifically looked at two members of zinc finger protein family: specificity protein 1 (SP1) and early grown response 1 transcription factors (EGR1). When the valence band is filled, we find electrons in the purines along the nucleotide sequence, compatible with the electric charges of the binding amino acids in SP1 and EGR1 zinc finger.

  8. Analysis of Codon Usage Patterns in Herbaceous Peony (Paeonia lactiflora Pall. Based on Transcriptome Data

    Directory of Open Access Journals (Sweden)

    Yanqing Wu

    2015-10-01

    Full Text Available Codon usage bias, which exists in many genomes, is mainly determined by mutation and selection. To elucidate the genetic features and evolutionary history of herbaceous peony (Paeonia lactiflora, a well-known symbol of prosperity in China, we examined synonymous codon usage in 24,216 reconstructed genes from the P. lactiflora transcriptome. The mean GC content was 44.4%, indicating that the nucleotide content of P. lactiflora genes is slightly AT rich and GC poor. The P. lactiflora genome has a wide range of GC3 (GC content at the third synonymous codon position distribution, with a significant correlation between GC12 and GC3. ENC (effective number of codons analysis suggested that mutational bias played a major role in shaping codon usage. Parity Rule 2 (PR2 analysis revealed that GC and AU were not used proportionally. We identified 22 “optimal codons”, most ending with an A or U. Our results suggested that nucleotide composition mutation bias and translational selection were the main driving factors of codon usage bias in P. lactiflora. These results lay the foundation for exploring the evolutionary mechanisms and heterologous expression of functionally-important proteins in P. lactiflora.

  9. Phenolic Compounds from Halimodendron halodendron (Pall. Voss and Their Antimicrobial and Antioxidant Activities

    Directory of Open Access Journals (Sweden)

    Jihua Wang

    2012-09-01

    Full Text Available Halimodendron halodendron has been used as forage in northwestern China for a long time. Its young leaves and flowers are edible and favored by indigenous people. In this study, eleven phenolic compounds were bioassay-guided and isolated from the aerial parts of H. halodendron for the first time. They were identified by means of physicochemical and spectrometric analysis as quercetin (1, 3,5,7,8,4'-pentahydroxy-3'-methoxy flavone (2, 3-O-methylquercetin (3, 3,3'-di-O-methylquercetin (4, 3,3'-di-O-methylquercetin-7-O-β-D-glucopyranoside (5, isorhamentin-3-O-β-D-rutinoside (6, 8-O-methylretusin (7, 8-O-methylretusin-7-O-β-D-glucopyranoside (8, salicylic acid (9, p-hydroxybenzoic acid (ferulic acid (10, and 4-hydroxy-3-methoxy cinnamic acid (11. They were sorted as flavonols (1–6, soflavones (7 and 8, and phenolic acids (9–11. Among the compounds, flanools 1–4 revealed a strong antibacterial activity with minimum inhibitory concentration (MIC values of 50–150 μg/mL, and median inhibitory concentration (IC50 values of 26.8–125.1 μg/mL. The two isoflavones (7 and 8 showed moderate inhibitory activity on the test bacteria. Three phenolic acids (9, 10 and 11 showed strong antibacterial activity with IC50 values of 28.1–149.7 μg/mL. Antifungal activities of the compounds were similar to their antibacterial activities. All these phenolic compounds showed significant antimicrobial activity with a broad spectrum as well as antioxidant activity based on 1,1-diphenyl-2-picrylhydrazyl (DPPH radical scavenging and β-carotene-linoleic acid bleaching assays. In general, the flavonol aglycones with relatively low polarity exhibited stronger activities than the glycosides. The results suggest the potential of this plant as a source of functional food ingredients and provide support data for its utilization as forage as well.

  10. Preventing microbial growth on pall-rings when upgrading biogas using absorption with water wash

    Energy Technology Data Exchange (ETDEWEB)

    Haakansson, Anna

    2006-07-15

    For produced biogas to be usable as vehicle fuel it has to be upgraded to a higher energy content. This is accomplished by elevation of the methane concentration through removal of carbon dioxide. Absorption with water wash is the most common upgrading method used in Sweden today. The upgrading technique is based on the fact that carbon dioxide is more soluble in water than methane. Upgrading plants that utilises this method have problems with microbial growth in the system. This growth eventually leads to a stop in operation due to the gradually drop in upgrading capacity. The aim of this thesis were to evaluate the possibility to through some kind of water treatment maintain an acceptable level of growth or altogether prevent it in order to maintain an acceptable process capacity and thereby avoid the need to clean. Through collection of literature the implementation possibilities were evaluated with regard to efficiency, economic sustainability and if there would be a release of any harmful substances. In order to prevent the microbial growth in the columns the treatment should either focus on removing microorganisms or limit the accessible nutrients. For the single pass system it is concluded that the treatment should reduce the biofilm formation and be employed in an intermittent way. Among the evaluated treatments focusing on the reduction of microorganisms the addition of peracetic acid seems to be the most promising one. For the regenerating system the treatment method could focus on either one. As for the single pass system peracetic acid could be added to reduce the amount of microorganism. To reduce the amount of organic matter an advanced oxidation process could be deployed with the advantage that it also could remove the microorganisms.

  11. Effect of Lanthanum on Methanol Fuel Exhaust Deep Oxidation over Pall adium Catalyst

    Institute of Scientific and Technical Information of China (English)

    王幸宜; 万颖; 卢冠忠

    2003-01-01

    The performance of deep oxidation of methanol on supported Pd catalyst was examined by a chromatograph-micro-reactor. The results show that the addition of La into γ-Al2O3 support can affect greatly the performance of the Pd catalyst. In the absence of CO, La can decrease the content of oxygen-containing intermediate, although La can not lower the light-off temperature of methanol oxidation. In the presence of CO, La can lower the light-off temperature, decrease the amount of CO adsorption, and weaken evidently "CO inhibition" to the oxidation of methanol. By XPS technique, it is shown that La modifies the electronic structure of Pd, which attributes to the modifications of the catalytic performance.

  12. [Genotypic Diversity of Wolbachia pipientis in Native and Invasive Harmonia axyridis Pall., 1773 (Coleoptera, Coccinellidae) Populations].

    Science.gov (United States)

    Goryacheva, I I; Blekhman, A V; Andrianov, B V; Gorelova, T V; Zakharov, I A

    2015-08-01

    The distribution and variability of reproductive symbiotic Wolbachia pipientis bacteria were studied in seven native and six invasive H. axyridis populations. Wolbachia-infected individuals were found in two invasive and two native populations. We demonstrated for the first time an infection of invasive H. axyridis populations with Wolbachia. Two new molecular forms of Wolbachia were detected by a system of multilocus typing. The supergroup A Wolbachia was found for the first time in H. axyridis. The detected genotypic diversity of Wolbachia indicates repeated and independent infection events in the evolutionary past of H. axyridis.

  13. Modelling

    CERN Document Server

    Spädtke, P

    2013-01-01

    Modeling of technical machines became a standard technique since computer became powerful enough to handle the amount of data relevant to the specific system. Simulation of an existing physical device requires the knowledge of all relevant quantities. Electric fields given by the surrounding boundary as well as magnetic fields caused by coils or permanent magnets have to be known. Internal sources for both fields are sometimes taken into account, such as space charge forces or the internal magnetic field of a moving bunch of charged particles. Used solver routines are briefly described and some bench-marking is shown to estimate necessary computing times for different problems. Different types of charged particle sources will be shown together with a suitable model to describe the physical model. Electron guns are covered as well as different ion sources (volume ion sources, laser ion sources, Penning ion sources, electron resonance ion sources, and H$^-$-sources) together with some remarks on beam transport.

  14. model

    African Journals Online (AJOL)

    trie neural construction oí inoiviouo! unci communal identities in ... occurs, Including models based on Information processing,1 ... Applying the DSM descriptive approach to dissociation in the ... a personal, narrative path lhal connects personal lo ethnic ..... managed the problem in the context of the community, using a.

  15. Modeling of dual cylinder wind-up extensional rheometers

    DEFF Research Database (Denmark)

    Yu, Kaijia; Marin, Jose; Jensen, Mette

    .L. Sentmanat, Rheol Acta, 43:657--669, 2004. [2] J.M.R. Marín, H.K.Rasmussen, J. Non-Newtonian Fluid Mech, 156 (3) , p. 177-188. [3] K.Y, J.M.R. Marín, H.K.Rasmussen, O.Hassager, J. Non-Newtonian Fluid Mech, 165 (1) , p. 14-23. [4] Y.Wang, P.Boukany, S.Wang, X.Wang, Physical Review Letters, 99, 237801 (2007...... a finite element technique based on a Lagrangian kinematics description of the 3D time-dependent flow of K-BKZ type fluids [2] is used to simulate extension flow of both cylindrical and strip shaped sample in the SER. Here the purpose is to discuss the potential deviations from ideal uni-axial deformation...

  16. Guiding young adults at risk

    DEFF Research Database (Denmark)

    Andreasen, Karen Egedal; Rasmussen, Palle Damkjær; Ydesen, Christian

    2016-01-01

    Karen Egedal Andreasen, Palle Rasmussen and Christian Ydesen question in their article, how to guide youth in danger of being marginalised or excluded from society in general and the labour market in particular. They analyse the guidance dimension in the youth in development project as described...... in the project and by the youths participating in the project. The project was designed to facilitate and support transition to an adult life by giving participants social support, feedback, experiences, room for reflection and feeling of acceptance and inclusion. In Denmark all social work with young people...... at risk involves guidance to “the right path”, since individual guidance seems to be the key asset in mobilizing young person’s needs and experiences. The article indicates important elements in the guidance of youth at risk, such as psychological intervention and personal support, support from...

  17. Late quaternary evolution of the Meuse fluvial system and its sediment composition : a reconstruction based on bulk sample geochemistry and forward modelling

    NARCIS (Netherlands)

    Tebbens, L.A.

    1999-01-01

    <p>All fluvial systems ultimately drain into alluvial basins, where the weathering products of their upstream drainage areas accumulate over a time-span varying from 10 0to 10 6years. Most silted-up alluvial basins are low-gradient deltas that are

  18. Mechanical Tissue Resuscitation Treatment Reduces Brain Tissue Volume and Intracerebral Hemorrhage and Increases Blood Perfusion in a Traumatic Brain Injury Model in Swine

    Science.gov (United States)

    2010-01-01

    extremities.(Covey, 2006; Geiger, 2008; Leininger , 2006) It is also used to successfully treat injuries associated with high energy trauma...case report and the role of vacuum-assisted wound closure dressing. J Orthop Trauma 19:748- 50. Leininger BE, Rasmussen TE, Smith DL, Jenkins DH

  19. Can Household Benefit from Stochastic Programming Models?

    DEFF Research Database (Denmark)

    Rasmussen, Kourosh Marjani; Madsen, Claus A.; Poulsen, Rolf

    2014-01-01

    The Danish mortgage market is large and sophisticated. However, most Danish mortgage banks advise private home-owners based on simple, if sensible, rules of thumb. In recent years a number of papers (from Nielsen and Poulsen in J Econ Dyn Control 28:1267–1289, 2004 over Rasmussen and Zenios in J.......3–0.9 %-points (depending on the borrower’s level of conservatism) compared to the rules of thumb without increasing the risk. The answer to the question in the title is thus affirmative....

  20. Elongational viscosity of narrow molar mass distribution polystyrene. Anders Bach, Kristoffer Almdal, Henrik Koblitz Rasmussen and Ole Hassager

    DEFF Research Database (Denmark)

    Rasmussen, Henrik Koblitz; Bach, Anders; Almdal, Kristoffer

    2003-01-01

    Transient and steady elongational viscosity has been measured for two narrow molar mass distribution polystyrene melts of molar masses 200 000 and 390 000 by means of a filament stretching rheometer. Total Hencky strains of about five have been obtained. The transient elongational viscosity rises...

  1. Elongational viscosity of narrow molar mass distribution polystyrene. Anders Bach, Kristoffer Almdal, Henrik Koblitz Rasmussen and Ole Hassager

    DEFF Research Database (Denmark)

    Rasmussen, Henrik Koblitz; Bach, Anders; Almdal, Kristoffer

    2003-01-01

    Transient and steady elongational viscosity has been measured for two narrow molar mass distribution polystyrene melts of molar masses 200 000 and 390 000 by means of a filament stretching rheometer. Total Hencky strains of about five have been obtained. The transient elongational viscosity rises...

  2. Numerical modeling of polar mesocyclones generation mechanisms

    Science.gov (United States)

    Sergeev, Dennis; Stepanenko, Victor

    2013-04-01

    parameters, lateral boundary conditions are varied in the typically observed range. The approach is fully nonlinear: we use a three-dimensional non-hydrostatic mesoscale model NH3D_MPI [1] coupled with one-dimensional water body model LAKE. A key method used in the present study is the analysis of eddy kinetic and available potential energy budgets. References 1. Mikushin, D.N., and Stepanenko, V.M., The implementation of regional atmospheric model numerical algorithms for CBEA-based clusters. Lecture Notes in Computer Science, Parallel Processing and Applied Mathematics, 2010, vol. 6067, p. 525-534. 2. Rasmussen, E., and Turner, J. (eds), Polar Lows: Mesoscale Weather Systems in the Polar Regions. Cambridge: Cambridge University Press, 2003, 612 pp. 3. Yanase, W., and Niino, H., Dependence of Polar Low Development on Baroclinicity and Physical Processes: An Idealized High-Resolution Experiment, J. Atmos. Sci., 2006, vol. 64, p. 3044-3067.

  3. Effect of Calcium Sprays on Mechanical Strength and Cell Wall Fractions of Herbaceous Peony (Paeonia Lactiflora Pall. Inflorescence Stems

    Directory of Open Access Journals (Sweden)

    Jintao Ge

    2012-04-01

    Full Text Available Calcium is an essential element and imparts significant structural rigidity to the plant cell walls, which provide the main mechanical support to the entire plant. In order to increase the mechanical strength of the inflorescence stems of herbaceous peony, the stems are treated with calcium chloride. The results shows that preharvest sprays with 4% (w/v calcium chloride three times after bud emergence are the best at strengthening “Da Fugui” peonies’ stems. Calcium sprays increased the concentrations of endogenous calcium, total pectin content as well as cell wall fractions in herbaceous peonies stems, and significantly increased the contents of them in the top segment. Correlation analysis showed that the breaking force of the top segment of peonies’ stems was positively correlated with the ratio of water insoluble pectin to water soluble pectin (R = 0.673 as well as lignin contents (R = 0.926 after calcium applications.

  4. Prevention and Control of Gentiana macrophylla Pall Root Rot Disease%秦艽根腐病的防治

    Institute of Scientific and Technical Information of China (English)

    程远辉; 侯志江; 徐中志

    2014-01-01

    The root rot is a major disease affecting yield of Gentiana macrophyl a pal , reducing yield or even causing total crop failure. This research introduced the occurrence characteristics and various control techniques of root rot of Gentiana macrophyl a pal , in order to provide references for farmers.%根腐病是影响秦艽产量的最主要病害,发病后会造成秦艽严重减产甚至绝收。笔者总结了秦艽根腐病的发生特点及各种防治技术,以期为广大药农提供指导。

  5. ON THE PROBLEM OF SPATIAL DEMOGRAPHIC STRUCTURE AND ONTOGENESIS OF HALOCNEMUM STROBILACEUM [(PALL. BIEB.] IN THE REPUBLIC OF KALMYKIA

    Directory of Open Access Journals (Sweden)

    V. G. Lazareva

    2016-01-01

    Full Text Available The aim of research is to study coenopopulations of Halocnemum strobilaceum on soft salt marshes of the lake "Cagan USN" (Yashkul district, Republic of Kalmykia.Materials and methods. The article presents data on the ontogeny, demographic and spatial structure of H. strobilaceum for practical and theoretical use due to the degradation of pastures and secondary salinity in the water reclamation. Research on coenopopulations of Halocnemum has been carried out according to the methods of studying spatial and demographic structure of the plant phytocenoses (1950, plant collection and herbarization (1977, and making sites of 3x3 meters.Results. Research has allowed us to identify 6 age phases of H. strobilaceum: p, im, v, g1, g2-g3, svg, s, and the ontogenetic state: p - 5%, im - 5%, v - 5%, g1 - 35 %, g2-g3 - 35%, svg - 5%, s - 10%. During the research of coenopopulations of Halocnemum strobilaceum we have revealed the polyvariance ontomorphogenesis phenomenon, which is manifested in the transition of individuals from senile (s age condition, in particular, to senile-virginal-generative (svg. In addition, at this stage, we have observed new shoots, habitually similar to vegetative, able to bloom the following year (the state svg. The analysis of ontogenesis of individuals of Halocnemum strobilaceum has showed the predominance of young (g1 and middle-aged (g2-g3 generative phase.Conclusion. Thus, a temporary rejuvenation of Halocnemum strobilaceum communities at the lake of "Cagan USN" is considered by us as the occurrence of certain adaptations to the effects of different natural and anthropogenic factors. This ability of Halocnemum strobilaceum to quickly restore spatial demographic structure of its coenopopulations indicates the high ecological and biological potential of this kind of dominant on the soft salt marshes.

  6. Supporting productive thinking: The semiotic context for Cognitive Systems Engineering (CSE).

    Science.gov (United States)

    Flach, John

    2017-03-01

    The central thesis of this paper is that Rasmussen framed his approach to Cognitive Systems Engineering from the perspective of a Triadic Semiotic Model. This frame became the context for integrating multiple intellectual threads including Control Theory, Information Theory, Ecological Psychology, and Gestalt Psychology into a coherent theoretical framework. The case is made that the triadic semiotic framework is essential for a complete appreciation of the constructs that were central to Rasmussen's approach: Abstraction Hierarchy, Skill-Rules-Knowledge Model, Ecological Interface Design, and Proactive Risk Management.

  7. Error-associated behaviors and error rates for robotic geology

    Science.gov (United States)

    Anderson, Robert C.; Thomas, Geb; Wagner, Jacob; Glasgow, Justin

    2004-01-01

    This study explores human error as a function of the decision-making process. One of many models for human decision-making is Rasmussen's decision ladder [9]. The decision ladder identifies the multiple tasks and states of knowledge involved in decision-making. The tasks and states of knowledge can be classified by the level of cognitive effort required to make the decision, leading to the skill, rule, and knowledge taxonomy (Rasmussen, 1987). Skill based decisions require the least cognitive effort and knowledge based decisions require the greatest cognitive effort. Errors can occur at any of the cognitive levels.

  8. Error-associated behaviors and error rates for robotic geology

    Science.gov (United States)

    Anderson, Robert C.; Thomas, Geb; Wagner, Jacob; Glasgow, Justin

    2004-01-01

    This study explores human error as a function of the decision-making process. One of many models for human decision-making is Rasmussen's decision ladder [9]. The decision ladder identifies the multiple tasks and states of knowledge involved in decision-making. The tasks and states of knowledge can be classified by the level of cognitive effort required to make the decision, leading to the skill, rule, and knowledge taxonomy (Rasmussen, 1987). Skill based decisions require the least cognitive effort and knowledge based decisions require the greatest cognitive effort. Errors can occur at any of the cognitive levels.

  9. Self-Determination and Bilingualism

    Science.gov (United States)

    Landry, Rodrigue; Allard, Real; Deveau, Kenneth

    2009-01-01

    This article focuses on additive bilingualism for minority group children, more specifically the development of strong literacy skills in English and in the children's language. The personal autonomization language learning (PALL) model is presented. It specifies eight testable hypotheses. Self-determination theory (SDT) is central in the PALL…

  10. User’s Manual for the AFSATCOM Terminal Upgrades Life Cycle Cost Model. Volume I.

    Science.gov (United States)

    1981-10-01

    roimber ot groupings. onuly the average - 11(1 to he1 ,pecif ie elt br mo, of the parameters A c r-,e Lt. I I ! iew. thev lidit it-tt lonl anld class if...training by the production contractor; - Type 2 is Air Force service training performed by Type 1 trainees ; - Recurring training is that necessitated...class hours per day for a type 2 training class. PALl = average daily pay and allowance during training for a type I trainee . PAL2B = average daily pay

  11. Uncertainty in Steady-State Diagnostics of a Current-Pressure Transducer: How Confident are We in Diagnosing Faults

    Science.gov (United States)

    2014-10-02

    though the hyperparameters may have estimated previously. For details of this method, refer to (Rasmussen, 2004; Chiles & Delfiner , 1999). Once the...non-Gaussian Bayesian tracking. IEEE Transactions on Signal Processing, 50(2), 174–188. Chiles, J., & Delfiner , P. (1999). Geostatistics: modeling

  12. Parallel Computing in Information Retrieval--An Updated Review.

    Science.gov (United States)

    Macfarlane, A.; And Others

    1997-01-01

    Reviews the progress of parallel computing in information retrieval (IR) and stresses the importance of the motivation in using parallel computing for text retrieval. Analyzes parallel IR systems using a classification defined by Rasmussen; describes retrieval models used in parallel information processing; and suggests areas of needed research.…

  13. Optimizing the use of Limb Tourniquets in Tactical Combat Casualty Care: TCCC Guidelines Change 14-02

    Science.gov (United States)

    2014-02-01

    American Civil War in 1862, Samuel Gross of the Union Army recommended issuing a tourniquet-like device to every combat soldier along with...K, Dixon P, Cowart J, Spencer J, Rasmussen TE. Hemorrhagic shock worsens neuromuscular recovery in a porcine model of hind limb vascular injury and

  14. Fuel moisture content estimation: a land-surface modelling approach applied to African savannas

    Science.gov (United States)

    Ghent, D.; Spessa, A.; Kaduk, J.; Balzter, H.

    2009-04-01

    (IPCC 2007). The simulation of realistic fire disturbance regimes with biophysical and biogeochemical models is a prerequisite for reducing the uncertainty of the African carbon cycle, and the feedbacks associated with this cycle and the global climate system. Using multi-temporal modelling analysis techniques, we present preliminary results that provide a more robust estimation of live FMC. References Chuvieco, E., Aguado, I. and Dimitrakopoulos, A. P. (2004) Conversion of fuel moisture content values to ignition potential for integrated fire danger assessment. Canadian Journal of Forest Research-Revue Canadienne De Recherche Forestiere 34(11): 2284-2293. IPCC (2007) 'Climate Change 2007: Synthesis Report. Contribution of Working Groups I, II and III to the Fourth Assessment Report of the Intergovernmental Panel on Climate Change [Core Writing Team, Pachauri, R.K and Reisinger, A. (eds.)].' IPCC, (Geneva, Switzerland). Lehsten, V., Tansey, K. J., Balzter, H, Thonicke, K., Spessa, A., Weber, U., Smith, B., and Arneth, A. (2008). Estimating carbon emissions from African wildfires. Accepted Biogeosciences. Sandholt, I., Rasmussen, K. & Andersen, J. (2002) A simple interpretation of the surface temperature/vegetation index space for assessment of surface moisture status. Remote Sensing of Environment 79(2-3): 213-224. Scholes, R. J., Ward, D. E. and Justice, C. O. (1996) Emissions of trace gases and aerosol particles due to vegetation burning in southern hemisphere Africa. Journal of Geophysical Research-Atmospheres 101(D19): 23677-23682. Snyder, R. L., Spano, D., Duce, P., Baldocchi, D., Xu, L. K. & Kyaw, T. P. U. (2006) A fuel dryness index for grassland fire-danger assessment. Agricultural and Forest Meteorology 139(1-2): 1-11.

  15. Application of Gaussian Process Modeling to Analysis of Functional Unreliability

    Energy Technology Data Exchange (ETDEWEB)

    R. Youngblood

    2014-06-01

    This paper applies Gaussian Process (GP) modeling to analysis of the functional unreliability of a “passive system.” GPs have been used widely in many ways [1]. The present application uses a GP for emulation of a system simulation code. Such an emulator can be applied in several distinct ways, discussed below. All applications illustrated in this paper have precedents in the literature; the present paper is an application of GP technology to a problem that was originally analyzed [2] using neural networks (NN), and later [3, 4] by a method called “Alternating Conditional Expectations” (ACE). This exercise enables a multifaceted comparison of both the processes and the results. Given knowledge of the range of possible values of key system variables, one could, in principle, quantify functional unreliability by sampling from their joint probability distribution, and performing a system simulation for each sample to determine whether the function succeeded for that particular setting of the variables. Using previously available system simulation codes, such an approach is generally impractical for a plant-scale problem. It has long been recognized, however, that a well-trained code emulator or surrogate could be used in a sampling process to quantify certain performance metrics, even for plant-scale problems. “Response surfaces” were used for this many years ago. But response surfaces are at their best for smoothly varying functions; in regions of parameter space where key system performance metrics may behave in complex ways, or even exhibit discontinuities, response surfaces are not the best available tool. This consideration was one of several that drove the work in [2]. In the present paper, (1) the original quantification of functional unreliability using NN [2], and later ACE [3], is reprised using GP; (2) additional information provided by the GP about uncertainty in the limit surface, generally unavailable in other representations, is discussed

  16. CROSSWORK for Glycans: Glycan Identificatin Through Mass Spectrometry and Bioinformatics. / Rasmussen, Morten ; Thaysen-Andersen, Morten ; Højrup, Peter. 2009

    DEFF Research Database (Denmark)

    Rasmussen, Morten

    Chemical cross-linking is a useful method for deriving information on protein structure and protein-protein interaction. We have developed a method combining chemical cross-linking with mass-spectrometry and bioinformatics (CrossWork) to automate search and validation of cross-links in large...

  17. Viscosity overshoot followed by steady state measured in uni-axial elongation of LDPE. Ole Hassager, Henrik Koblitz Rasmussen, Anders Bach and Jens Kromann Nielsen

    DEFF Research Database (Denmark)

    Rasmussen, Henrik Koblitz; Hassager, Ole; Bach, Anders

    2004-01-01

    The transient (e.g. start up of) elongational viscosity of three low-density polyethylene (LDPE) melts (BASF Lupolen 1810H, 1840D and 3020D) was measured using a filament stretching rheometer (FSR) capable of measuring at elevated temperatures. The transient uni-axial elongational viscosity showe...

  18. 拉宾威兹·拉斯穆森:“价值的回归”%Rabinowicz,W.,and Rasmussen,R.,"Tropic of Value"

    Institute of Scientific and Technical Information of China (English)

    刘钢

    2003-01-01

    我们早些时候曾经论证过诸如事物和人等具体的对象可以具有最终的价值(出于它们自身目的的价值),这些价值是无法还原为涉及到所讨论的对象的事态的价值。

  19. Injection Moulded Plastic Parts with Surface Microstructures. U. R. Arlø, E. M. Kjær and H. K. Rasmussen

    DEFF Research Database (Denmark)

    Rasmussen, Henrik Koblitz; Arlø, Uffe Rolf; Kjær, Erik Michael

    2001-01-01

    The development of microstructures is a growing industry. The technological development is working towards smaller products and structures, opening up new areas for exploitation. In the following the design and the fabrication of the microstructures will be presented.......The development of microstructures is a growing industry. The technological development is working towards smaller products and structures, opening up new areas for exploitation. In the following the design and the fabrication of the microstructures will be presented....

  20. Clinical course and variability of non-Rasmussen, nonstroke motor and sensory epilepsia partialis continua: a European survey and analysis of 65 cases

    DEFF Research Database (Denmark)

    Mameniskiene, Ruta; Bast, Thomas; Bentes, Carla

    2011-01-01

    To gain new insights into the clinical presentation, causes, treatment and prognosis of epilepsia partialis continua (EPC), and to develop hypotheses to be tested in a prospective investigation.......To gain new insights into the clinical presentation, causes, treatment and prognosis of epilepsia partialis continua (EPC), and to develop hypotheses to be tested in a prospective investigation....

  1. Transient extensional viscosity of polymer melts in the filament stretching rheometer. A. Bach, H. Bastian, M.H. Wagner, H.K. Rasmussen and O. Hassager

    DEFF Research Database (Denmark)

    Rasmussen, Henrik Koblitz; Bach, Anders; Bastian, Heike

    2002-01-01

    In many polymer processing operations, the polymer molecules becomes highly elongated and the extensional viscosity becomes an inportant parameter in estimating properties during and after the process....

  2. Characterization of polymers by bubble inflation, Jens H. Christensen, Henrik K. Rasmussen, Erik M. Kjær and Carsten L. Lauridsen

    DEFF Research Database (Denmark)

    Rasmussen, Henrik Koblitz; Christensen, Jens H.; Kjær, Erik Michael;

    1999-01-01

    In order to characterize materials using a simple and relative inexpensive method, the bubble inflation technique was modified. A polymer plate is clamped between a Teflon coated plate and a heated cylinder. By applying air through the heating plate the polymer membrane deforms into the cylinder...

  3. Transient extensional viscosity of polymer melts in the filament stretching rheometer. A. Bach, H. Bastian, M.H. Wagner, H.K. Rasmussen and O. Hassager

    DEFF Research Database (Denmark)

    Rasmussen, Henrik Koblitz; Bach, Anders; Bastian, Heike

    2002-01-01

    In many polymer processing operations, the polymer molecules becomes highly elongated and the extensional viscosity becomes an inportant parameter in estimating properties during and after the process....

  4. Viscosity overshoot followed by steady state measured in uni-axial elongation of LDPE. Ole Hassager, Henrik Koblitz Rasmussen, Anders Bach and Jens Kromann Nielsen

    DEFF Research Database (Denmark)

    Rasmussen, Henrik Koblitz; Hassager, Ole; Bach, Anders

    2004-01-01

    The transient (e.g. start up of) elongational viscosity of three low-density polyethylene (LDPE) melts (BASF Lupolen 1810H, 1840D and 3020D) was measured using a filament stretching rheometer (FSR) capable of measuring at elevated temperatures. The transient uni-axial elongational viscosity showe...

  5. A study on the NMR spectrum of monoterpene glucosides from Paeonia lactiflora Pall.%芍药单萜苷的NMR谱学研究

    Institute of Scientific and Technical Information of China (English)

    张晓燕; 王金辉; 李铣

    2001-01-01

    A study on the NMR spectral character of paeoniflorin, amonoterpene glucoside, was carried out and its proton signals of 1H-NMR were completely assigned by means of HMQC、HMBC、1H-1H COSY and ROSEY for the first time.%利用HMBC,HMQC,1H-1HCOSY,ROSEY等核磁技术第一次完整地确定了芍药苷中碳氢信号的归属。

  6. The invasion history, distribution and colour pattern forms of the harlequin ladybird beetle Harmonia axyridis (Pall. (Coleoptera, Coccinellidae in Slovakia, Central Europe

    Directory of Open Access Journals (Sweden)

    Ľubomír Panigaj

    2014-05-01

    Full Text Available The harlequin ladybird beetle Harmonia axyridis (Coleoptera, Coccinellidae has invaded and established in Slovakia. Following unintentional introduction in 2008, the spread of the alien coccinellid was very fast. By the end of 2009, it was recorded across the whole country, and by the end of 2012 it was widely distributed and common in various habitats, particularly gardens, orchards and urban areas, where it was most frequent on trees. The rate of eastward spread was approximately 200 km year-1, similar to the overall rate of spread in Europe. Between 2008 and 2012, the coccinellid was recorded in a total of 153 localities, in altitudes ranging from 98 to 1,250 m. Most records of this species were made in lowlands, hilly areas and valleys separating mountain ridges. However, it was only rarely documented in areas above 700 m a.s.l. The non-melanic colour form (f. succinea was dominant along alongitudinal transect including eight urban areas across Slovakia, with the frequency of melanic forms (f. spectabilis and f. conspicua together between 6.3 and 19.2% and a median equal to 10.5%. The invasion history and distribution of H. axyridis in Slovakia are discussed with regard to the time sequence of records, rate of spread, altitudinal distribution, anthropogenic dispersal, effective recording, proportion of melanic forms and other relevant aspects associated with the spread of this successful invader.

  7. Muusikamaailm : CPE Bachi käsikirjad tagasi Saksamaale. Täna uusooper Londonis. Theodorakise ooperid plaadil. David Golub lahkunud. Preemia Palle Mikkelborgile / Priit Kuusk

    Index Scriptorium Estoniae

    Kuusk, Priit, 1938-

    2001-01-01

    Ukraina nõustus tagastama Saksamaale C.P.E. Bachi muusikakäsikirjad, mis Nõukogude Liidu armee sealt II Maailmasõja ajal ära viis. Inglise Rahvusooperis lavastuvast D.Saweri ooperist "From Morning to Midnight". M.Theodorakise kolm ooperit (antiiktriloogia "Elektra", "Antigone" ja "Medeia") ilmusid seoses maestro 75. juubeliga kaheksal CD-plaadil. Lühidalt D.Golubist. Põhjamaade Nõukogu tänavuse muusikapreemia võitis P.Mikkelborg

  8. The invasion history, distribution and colour pattern forms of the harlequin ladybird beetle Harmonia axyridis (Pall.) (Coleoptera, Coccinellidae) in Slovakia, Central Europe.

    Science.gov (United States)

    Panigaj, Lubomír; Zach, Peter; Honěk, Alois; Nedvěd, Oldřich; Kulfan, Ján; Martinková, Zdenka; Selyemová, Diana; Viglášová, Sandra; Roy, Helen E

    2014-01-01

    The harlequin ladybird beetle Harmonia axyridis (Coleoptera, Coccinellidae) has invaded and established in Slovakia. Following unintentional introduction in 2008, the spread of the alien coccinellid was very fast. By the end of 2009, it was recorded across the whole country, and by the end of 2012 it was widely distributed and common in various habitats, particularly gardens, orchards and urban areas, where it was most frequent on trees. The rate of eastward spread was approximately 200 km year(-1), similar to the overall rate of spread in Europe. Between 2008 and 2012, the coccinellid was recorded in a total of 153 localities, in altitudes ranging from 98 to 1,250 m. Most records of this species were made in lowlands, hilly areas and valleys separating mountain ridges. However, it was only rarely documented in areas above 700 m a.s.l. The non-melanic colour form (f. succinea) was dominant along a longitudinal transect including eight urban areas across Slovakia, with the frequency of melanic forms (f. spectabilis and f. conspicua together) between 6.3 and 19.2% and a median equal to 10.5%. The invasion history and distribution of H. axyridis in Slovakia are discussed with regard to the time sequence of records, rate of spread, altitudinal distribution, anthropogenic dispersal, effective recording, proportion of melanic forms and other relevant aspects associated with the spread of this successful invader.

  9. 尼龙11/POE共混物的形态与力学性能%The Morphology and Mechanical Properties of PAll/POE Blends

    Institute of Scientific and Technical Information of China (English)

    郭云霞; 胡国胜; 李迎春; 杨云峰; 王志强

    2012-01-01

    采用动态力学分析(DMTA)和扫描电镜(SEM)等方法研究了相容剂乙烯辛烯共聚物接枝马来酸酐聚合物(POE-g-MAH)对尼龙11(PA11)共混体系力学性能及共混物形态的影响。结果表明,混合弹性体中m(POE-g-MAH)/m(POE)=2∶1时,PA11共混物的缺口冲击强度达到81.2 kJ/m^2;共混物缺口冲击强度对MAH接枝率敏感;加入混合弹性体,共混体系分子间的作用力增大,损耗峰向高温方向移动,Tg升高;PA11与POE各个共混体系的β松弛峰高显著低于纯PA11的,加入POE和POE-g-MAH可有效降低PA11的吸水性;POE-g-MAH可显著改善PA11/POE共混材料的相容性,使分散相尺寸减小,分布均匀,且材料缺口冲击强度显著增大。%The effect of maleic anhydride grafted polyolefin elastomer(POE-g-MAH) as compatilizer on the mechanical properties and morphology of polyamide 11(PA11)/POE blends was investigated using dynamic mechanical analysis(DMTA) and scanning electron microscope(SEM).The results show that when the ratio of POE-g-MAH and POE in mixed elastomer is 2:1,the notched impact strength of PA11 blends reaches 81.2 kJ/m2.The notched impact strength of blends is sensitive to MAH grafted rate.When mixed elastomer is added into PA11,the intermolecular forces of blends system increase and the loss peaks move to the high temperature which results in higher Tg.The β relaxation peak of each blends of PA11 and POE is significantly lower than that of pure PA11,which illustrates that POE and POE-g-MAH can effectively reduce water absorptivity of PA11.POE-g-MAH can improve the miscibility between PA11 and POE,decrease the particle size of dispersion phase and obviously increase the notched impact strength of these blends.

  10. Leadership Models.

    Science.gov (United States)

    Freeman, Thomas J.

    This paper discusses six different models of organizational structure and leadership, including the scalar chain or pyramid model, the continuum model, the grid model, the linking pin model, the contingency model, and the circle or democratic model. Each model is examined in a separate section that describes the model and its development, lists…

  11. Model Transformations? Transformation Models!

    NARCIS (Netherlands)

    Bézivin, J.; Büttner, F.; Gogolla, M.; Jouault, F.; Kurtev, I.; Lindow, A.

    2006-01-01

    Much of the current work on model transformations seems essentially operational and executable in nature. Executable descriptions are necessary from the point of view of implementation. But from a conceptual point of view, transformations can also be viewed as descriptive models by stating only the

  12. Modelling business models

    NARCIS (Netherlands)

    Simonse, W.L.

    2014-01-01

    Business model design does not always produce a “design” or “model” as the expected result. However, when designers are involved, a visual model or artifact is produced. To assist strategic managers in thinking about how they can act, the designers’ challenge is to combine both strategy and design n

  13. Modelling SDL, Modelling Languages

    Directory of Open Access Journals (Sweden)

    Michael Piefel

    2007-02-01

    Full Text Available Today's software systems are too complex to implement them and model them using only one language. As a result, modern software engineering uses different languages for different levels of abstraction and different system aspects. Thus to handle an increasing number of related or integrated languages is the most challenging task in the development of tools. We use object oriented metamodelling to describe languages. Object orientation allows us to derive abstract reusable concept definitions (concept classes from existing languages. This language definition technique concentrates on semantic abstractions rather than syntactical peculiarities. We present a set of common concept classes that describe structure, behaviour, and data aspects of high-level modelling languages. Our models contain syntax modelling using the OMG MOF as well as static semantic constraints written in OMG OCL. We derive metamodels for subsets of SDL and UML from these common concepts, and we show for parts of these languages that they can be modelled and related to each other through the same abstract concepts.

  14. Actant Models

    DEFF Research Database (Denmark)

    Poulsen, Helle

    1996-01-01

    This paper presents a functional modelling method called Actant Modelling rooted in linguistics and semiotics. Actant modelling can be integrated with Multilevel Flow Modelling (MFM) in order to give an interpretation of actants.......This paper presents a functional modelling method called Actant Modelling rooted in linguistics and semiotics. Actant modelling can be integrated with Multilevel Flow Modelling (MFM) in order to give an interpretation of actants....

  15. Modelling the models

    CERN Multimedia

    Anaïs Schaeffer

    2012-01-01

    By analysing the production of mesons in the forward region of LHC proton-proton collisions, the LHCf collaboration has provided key information needed to calibrate extremely high-energy cosmic ray models.   Average transverse momentum (pT) as a function of rapidity loss ∆y. Black dots represent LHCf data and the red diamonds represent SPS experiment UA7 results. The predictions of hadronic interaction models are shown by open boxes (sibyll 2.1), open circles (qgsjet II-03) and open triangles (epos 1.99). Among these models, epos 1.99 shows the best overall agreement with the LHCf data. LHCf is dedicated to the measurement of neutral particles emitted at extremely small angles in the very forward region of LHC collisions. Two imaging calorimeters – Arm1 and Arm2 – take data 140 m either side of the ATLAS interaction point. “The physics goal of this type of analysis is to provide data for calibrating the hadron interaction models – the well-known &...

  16. Modelling Practice

    DEFF Research Database (Denmark)

    2011-01-01

    This chapter deals with the practicalities of building, testing, deploying and maintaining models. It gives specific advice for each phase of the modelling cycle. To do this, a modelling framework is introduced which covers: problem and model definition; model conceptualization; model data...... requirements; model construction; model solution; model verification; model validation and finally model deployment and maintenance. Within the adopted methodology, each step is discussedthrough the consideration of key issues and questions relevant to the modelling activity. Practical advice, based on many...... years of experience is providing in directing the reader in their activities.Traps and pitfalls are discussed and strategies also given to improve model development towards “fit-for-purpose” models. The emphasis in this chapter is the adoption and exercise of a modelling methodology that has proven very...

  17. The Influence of Greenland melt water on the temporal and spatial response of the Holocene Thermal Maximum in the Nordic Seas: a modelling study

    Science.gov (United States)

    Blaschek, M.; Renssen, H.

    2012-04-01

    simulations are compared to proxy-based SST reconstructions from the Nordic Seas region. We find a better agreement between simulations including GIS melt and proxy-based SST reconstructions. According to marine proxy data the HTM is non-uniform over the Nordic Seas. Yielding higher SST near the Norwegian Coast and cooler near Greenland. The influence of the LIS explains part of this climate variability, but in the Denmark Strait, this forcing is not sufficient enough to explain reconstructed SST trends. Supporting the proposed significance of GIS melting as a regional contributor to climate change in the Nordic Seas. Peltier W, R. Global Glacial Isostasy and the Surface of the Ice-Age Earth: The ICE-5G (VM2) Model and GRACE. 2004. Annu. Rev. Earth Planet. Sci., 32:111-149. Renssen, H. and Seppä, H. and Heiri, O. and Roche D, M. and Goosse, H. and Fichefet, T. The spatial and temporal complexity of the Holocene thermal maximum. 2009. Nature Geoscience, 2(6):411-414. Vinther B, M. and Buchardt S, L. and Clausen H, B. and Dahl-Jensen, D. and Johnsen S, J. and Fisher D, a. and Koerner R, M. and Raynaud, D. and Lipenkov, V. and Andersen K, K. and Blunier, T. and Rasmussen S, O. and Steffensen J, P. and Svensson a, M. Holocene thinning of the Greenland ice sheet. 2009. Nature, 461(7262):385-388.

  18. Wave Induced Loads on the LEANCON Wave Energy Converter

    DEFF Research Database (Denmark)

    Frigaard, Peter; Kofoed, Jens Peter; Beserra, Eliab Ricarte

    This report is a product of the co-operation agreement between Aalborg University and LEANCON (by Kurt Due Rasmussen) on the evaluation and development of the LEANCON wave energy converter (WEC). The work reported here has focused on evaluation of the wave induced loads on the device, based...... on a desktop study based on available literature, supplemented by laboratory testing of models of the WEC provided by LEANCON. LEANCON, represented by Kurt Due Rasmussen, has been heavily involved in the testing of the device, including the instrumentation, model setup and execution of the tests...... in the laboratory, all under the supervision of the personnel of the Wave Energy Research Group at Department of Civil Engineering, Aalborg University....

  19. Promoting Models

    Science.gov (United States)

    Li, Qin; Zhao, Yongxin; Wu, Xiaofeng; Liu, Si

    There can be multitudinous models specifying aspects of the same system. Each model has a bias towards one aspect. These models often override in specific aspects though they have different expressions. A specification written in one model can be refined by introducing additional information from other models. The paper proposes a concept of promoting models which is a methodology to obtain refinements with support from cooperating models. It refines a primary model by integrating the information from a secondary model. The promotion principle is not merely an academic point, but also a reliable and robust engineering technique which can be used to develop software and hardware systems. It can also check the consistency between two specifications from different models. A case of modeling a simple online shopping system with the cooperation of the guarded design model and CSP model illustrates the practicability of the promotion principle.

  20. Cadastral Modeling

    DEFF Research Database (Denmark)

    Stubkjær, Erik

    2005-01-01

    Modeling is a term that refers to a variety of efforts, including data and process modeling. The domain to be modeled may be a department, an organization, or even an industrial sector. E-business presupposes the modeling of an industrial sector, a substantial task. Cadastral modeling compares to...

  1. South-East Region in Bulgaria: Economic Performance and Key Sectors Analysis

    OpenAIRE

    Golemanova, Antoaneta

    2008-01-01

    The present paper attempts to provide insight into the economic performance of the South-east region (SER) of Bulgaria by presenting quantitative relationships between sectors in the regional economy. Methodologically it is based on the construction of the regional Input–Output model. It was carried out trough applying the non-servey GRIT technique, based on Flegg & Webber location quotient (2000). The dirived Rasmussen & Hirschman backward linkages and Mattas & Shrestha input-output elastici...

  2. Remote Medical Diagnosis System (RMDS) Design Review Meeting Minutes 27-28 August 1980, held at Department of the Navy, Washington, DC.

    Science.gov (United States)

    1981-08-01

    Head Bioacoustics & Bionics Division Biosciences Department 7’. i" i S+1 Iŕ UNCLASSIFIED SECURITY CLASSIFICATION OF THIS PAGE (When Data Entered) REPOT...Transmitted and Received Images (Analog and Digital) of Eye Over ADM Terminals Via HF...19 i1 Project Plan...21 12 EDM Procurement Cycle Summary...22...received images (analog and digital) of eye over ADM terminals via hf. *1 19 -14. ENGINEERING DEVELOPMENT MODELS (EDMs) Dr. W. Rasmussen (NOSC): Many

  3. Glutamic acid decarboxylase autoimmunity in Batten disease and other disorders.

    Science.gov (United States)

    Pearce, David A; Atkinson, Mark; Tagle, Danilo A

    2004-12-14

    Degenerative diseases of the CNS, such as stiff-person syndrome (SPS), progressive cerebellar ataxia, and Rasmussen encephalitis, have been characterized by the presence of autoantibodies. Recent findings in individuals with Batten disease and in animal models for the disorder indicate that this condition may be associated with autoantibodies against glutamic acid decarboxylase (GAD), an enzyme that converts the excitatory neurotransmitter glutamate to the inhibitory neurotransmitter gamma-aminobutyric acid (GABA). Anti-GAD autoantibodies could result in excess excitatory neurotransmitters, leading to the seizures and other symptoms observed in patients with Batten disease. The pathogenic potential of GAD autoantibodies is examined in light of what is known for other autoimmune disorders, such as multiple sclerosis, SPS, Rasmussen encephalitis, and type 1 diabetes, and may have radical implications for diagnosis and management of Batten disease.

  4. Can breathing circuit filters help prevent the spread of influenza A (H1N1 virus from intubated patients?

    Directory of Open Access Journals (Sweden)

    Heuer, Jan F.

    2013-04-01

    Full Text Available [english] Introduction: In March 2010, more than 213 countries worldwide reported laboratory confirmed cases of influenza H1N1 infections with at least 16,813 deaths. In some countries, roughly 10 to 30% of the hospitalized patients were admitted to the ICU and up to 70% of those required mechanical ventilation. The question now arises whether breathing system filters can prevent virus particles from an infected patient from entering the breathing system and passing through the ventilator into the ambient air.We tested the filters routinely used in our institution for their removal efficacy and efficiency for the influenza virus A H1N1 (A/PR/8/34.Methods: Laboratory investigation of three filters (PALL Ultipor 25, Uor 100 and Pall BB50T Breathing Circuit Filter, manufactured by Pall Life Sciences using a monodispersed aerosol of human influenza A (H1N1 virus in an air stream model with virus particles quantified as cytopathic effects in cultured canine kidney cells (MDCK. Results: The initial viral load of 7.74±0.27 log was reduced to a viral load of ≤2.43 log, behind the filter. This represents a viral filtration efficiency of ≥99.9995%. Conclusion: The three tested filters retained the virus input, indicating that their use in the breathing systems of intubated and mechanically ventilated patients can reduce the risk of spreading the virus to the breathing system and the ambient air.

  5. Model Warehouse

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    This paper puts forward a new conception:model warehouse,analyzes the reason why model warehouse appears and introduces the characteristics and architecture of model warehouse.Last,this paper points out that model warehouse is an important part of WebGIS.

  6. Constitutive Models

    DEFF Research Database (Denmark)

    2011-01-01

    procedure is introduced for the analysis and solution of property models. Models that capture and represent the temperature dependent behaviour of physical properties are introduced, as well as equation of state models (EOS) such as the SRK EOS. Modelling of liquid phase activity coefficients are also......This chapter presents various types of constitutive models and their applications. There are 3 aspects dealt with in this chapter, namely: creation and solution of property models, the application of parameter estimation and finally application examples of constitutive models. A systematic...... covered, illustrating several models such as the Wilson equation and NRTL equation, along with their solution strategies. A section shows how to use experimental data to regress the property model parameters using a least squares approach. A full model analysis is applied in each example that discusses...

  7. Model cities

    OpenAIRE

    Batty, M.

    2007-01-01

    The term ?model? is now central to our thinking about how weunderstand and design cities. We suggest a variety of ways inwhich we use ?models?, linking these ideas to Abercrombie?sexposition of Town and Country Planning which represented thestate of the art fifty years ago. Here we focus on using models asphysical representations of the city, tracing the development ofsymbolic models where the focus is on simulating how functiongenerates form, to iconic models where the focus is on representi...

  8. Model theory

    CERN Document Server

    Chang, CC

    2012-01-01

    Model theory deals with a branch of mathematical logic showing connections between a formal language and its interpretations or models. This is the first and most successful textbook in logical model theory. Extensively updated and corrected in 1990 to accommodate developments in model theoretic methods - including classification theory and nonstandard analysis - the third edition added entirely new sections, exercises, and references. Each chapter introduces an individual method and discusses specific applications. Basic methods of constructing models include constants, elementary chains, Sko

  9. Event Modeling

    DEFF Research Database (Denmark)

    Bækgaard, Lars

    2001-01-01

    The purpose of this chapter is to discuss conceptual event modeling within a context of information modeling. Traditionally, information modeling has been concerned with the modeling of a universe of discourse in terms of information structures. However, most interesting universes of discourse...... are dynamic and we present a modeling approach that can be used to model such dynamics. We characterize events as both information objects and change agents (Bækgaard 1997). When viewed as information objects events are phenomena that can be observed and described. For example, borrow events in a library can...

  10. Event Modeling

    DEFF Research Database (Denmark)

    Bækgaard, Lars

    2001-01-01

    The purpose of this chapter is to discuss conceptual event modeling within a context of information modeling. Traditionally, information modeling has been concerned with the modeling of a universe of discourse in terms of information structures. However, most interesting universes of discourse...... are dynamic and we present a modeling approach that can be used to model such dynamics.We characterize events as both information objects and change agents (Bækgaard 1997). When viewed as information objects events are phenomena that can be observed and described. For example, borrow events in a library can...

  11. Numerical models

    Digital Repository Service at National Institute of Oceanography (India)

    Unnikrishnan, A; Manoj, N.T.

    Various numerical models used to study the dynamics and horizontal distribution of salinity in Mandovi-Zuari estuaries, Goa, India is discussed in this chapter. Earlier, a one-dimensional network model was developed for representing the complex...

  12. Computable models

    CERN Document Server

    Turner, Raymond

    2009-01-01

    Computational models can be found everywhere in present day science and engineering. In providing a logical framework and foundation for the specification and design of specification languages, Raymond Turner uses this framework to introduce and study computable models. In doing so he presents the first systematic attempt to provide computational models with a logical foundation. Computable models have wide-ranging applications from programming language semantics and specification languages, through to knowledge representation languages and formalism for natural language semantics. They are al

  13. MODELING CONSCIOUSNESS

    OpenAIRE

    Taylor, J G

    2009-01-01

    We present tentative answers to three questions: firstly, what is to be assumed about the structure of the brain in attacking the problem of modeling consciousness; secondly, what is it about consciousness that is attempting to be modeled; and finally, what is taken on board the modeling enterprise, if anything, from the vast works by philosophers about the nature of mind.

  14. Zeebrugge Model

    DEFF Research Database (Denmark)

    Sclütter, Flemming; Frigaard, Peter; Liu, Zhou

    This report presents the model test results on wave run-up on the Zeebrugge breakwater under the simulated prototype storms. The model test was performed in January 2000 at the Hydraulics & Coastal Engineering Laboratory, Aalborg University. The detailed description of the model is given...

  15. Interface models

    DEFF Research Database (Denmark)

    Ravn, Anders P.; Staunstrup, Jørgen

    1994-01-01

    This paper proposes a model for specifying interfaces between concurrently executing modules of a computing system. The model does not prescribe a particular type of communication protocol and is aimed at describing interfaces between both software and hardware modules or a combination of the two....... The model describes both functional and timing properties of an interface...

  16. Constitutive Models

    DEFF Research Database (Denmark)

    2011-01-01

    This chapter presents various types of constitutive models and their applications. There are 3 aspects dealt with in this chapter, namely: creation and solution of property models, the application of parameter estimation and finally application examples of constitutive models. A systematic...

  17. Model Experiments and Model Descriptions

    Science.gov (United States)

    Jackman, Charles H.; Ko, Malcolm K. W.; Weisenstein, Debra; Scott, Courtney J.; Shia, Run-Lie; Rodriguez, Jose; Sze, N. D.; Vohralik, Peter; Randeniya, Lakshman; Plumb, Ian

    1999-01-01

    The Second Workshop on Stratospheric Models and Measurements Workshop (M&M II) is the continuation of the effort previously started in the first Workshop (M&M I, Prather and Remsberg [1993]) held in 1992. As originally stated, the aim of M&M is to provide a foundation for establishing the credibility of stratospheric models used in environmental assessments of the ozone response to chlorofluorocarbons, aircraft emissions, and other climate-chemistry interactions. To accomplish this, a set of measurements of the present day atmosphere was selected. The intent was that successful simulations of the set of measurements should become the prerequisite for the acceptance of these models as having a reliable prediction for future ozone behavior. This section is divided into two: model experiment and model descriptions. In the model experiment, participant were given the charge to design a number of experiments that would use observations to test whether models are using the correct mechanisms to simulate the distributions of ozone and other trace gases in the atmosphere. The purpose is closely tied to the needs to reduce the uncertainties in the model predicted responses of stratospheric ozone to perturbations. The specifications for the experiments were sent out to the modeling community in June 1997. Twenty eight modeling groups responded to the requests for input. The first part of this section discusses the different modeling group, along with the experiments performed. Part two of this section, gives brief descriptions of each model as provided by the individual modeling groups.

  18. Scalable Models Using Model Transformation

    Science.gov (United States)

    2008-07-13

    and the following companies: Agilent, Bosch, HSBC , Lockheed-Martin, National Instruments, and Toyota. Scalable Models Using Model Transformation...parametrization, and workflow automation. (AFRL), the State of California Micro Program, and the following companies: Agi- lent, Bosch, HSBC , Lockheed

  19. Cadastral Modeling

    DEFF Research Database (Denmark)

    Stubkjær, Erik

    2005-01-01

    to the modeling of an industrial sector, as it aims at rendering the basic concepts that relate to the domain of real estate and the pertinent human activities. The palpable objects are pieces of land and buildings, documents, data stores and archives, as well as persons in their diverse roles as owners, holders...... to land. The paper advances the position that cadastral modeling has to include not only the physical objects, agents, and information sets of the domain, but also the objectives or requirements of cadastral systems.......Modeling is a term that refers to a variety of efforts, including data and process modeling. The domain to be modeled may be a department, an organization, or even an industrial sector. E-business presupposes the modeling of an industrial sector, a substantial task. Cadastral modeling compares...

  20. Modelling in Business Model design

    NARCIS (Netherlands)

    Simonse, W.L.

    2013-01-01

    It appears that business model design might not always produce a design or model as the expected result. However when designers are involved, a visual model or artefact is produced. To assist strategic managers in thinking about how they can act, the designers challenge is to combine strategy and

  1. Climate Models

    Science.gov (United States)

    Druyan, Leonard M.

    2012-01-01

    Climate models is a very broad topic, so a single volume can only offer a small sampling of relevant research activities. This volume of 14 chapters includes descriptions of a variety of modeling studies for a variety of geographic regions by an international roster of authors. The climate research community generally uses the rubric climate models to refer to organized sets of computer instructions that produce simulations of climate evolution. The code is based on physical relationships that describe the shared variability of meteorological parameters such as temperature, humidity, precipitation rate, circulation, radiation fluxes, etc. Three-dimensional climate models are integrated over time in order to compute the temporal and spatial variations of these parameters. Model domains can be global or regional and the horizontal and vertical resolutions of the computational grid vary from model to model. Considering the entire climate system requires accounting for interactions between solar insolation, atmospheric, oceanic and continental processes, the latter including land hydrology and vegetation. Model simulations may concentrate on one or more of these components, but the most sophisticated models will estimate the mutual interactions of all of these environments. Advances in computer technology have prompted investments in more complex model configurations that consider more phenomena interactions than were possible with yesterday s computers. However, not every attempt to add to the computational layers is rewarded by better model performance. Extensive research is required to test and document any advantages gained by greater sophistication in model formulation. One purpose for publishing climate model research results is to present purported advances for evaluation by the scientific community.

  2. Mathematical modelling

    CERN Document Server

    2016-01-01

    This book provides a thorough introduction to the challenge of applying mathematics in real-world scenarios. Modelling tasks rarely involve well-defined categories, and they often require multidisciplinary input from mathematics, physics, computer sciences, or engineering. In keeping with this spirit of modelling, the book includes a wealth of cross-references between the chapters and frequently points to the real-world context. The book combines classical approaches to modelling with novel areas such as soft computing methods, inverse problems, and model uncertainty. Attention is also paid to the interaction between models, data and the use of mathematical software. The reader will find a broad selection of theoretical tools for practicing industrial mathematics, including the analysis of continuum models, probabilistic and discrete phenomena, and asymptotic and sensitivity analysis.

  3. Turbulence Model

    DEFF Research Database (Denmark)

    Nielsen, Mogens Peter; Shui, Wan; Johansson, Jens

    2011-01-01

    In this report a new turbulence model is presented.In contrast to the bulk of modern work, the model is a classical continuum model with a relatively simple constitutive equation. The constitutive equation is, as usual in continuum mechanics, entirely empirical. It has the usual Newton or Stokes...... term with stresses depending linearly on the strain rates. This term takes into account the transfer of linear momentum from one part of the fluid to another. Besides there is another term, which takes into account the transfer of angular momentum. Thus the model implies a new definition of turbulence....... The model is in a virgin state, but a number of numerical tests have been carried out with good results. It is published to encourage other researchers to study the model in order to find its merits and possible limitations....

  4. Mathematical modelling

    DEFF Research Database (Denmark)

    Blomhøj, Morten

    2004-01-01

    Developing competences for setting up, analysing and criticising mathematical models are normally seen as relevant only from and above upper secondary level. The general belief among teachers is that modelling activities presuppose conceptual understanding of the mathematics involved. Mathematical...... modelling, however, can be seen as a practice of teaching that place the relation between real life and mathematics into the centre of teaching and learning mathematics, and this is relevant at all levels. Modelling activities may motivate the learning process and help the learner to establish cognitive...... roots for the construction of important mathematical concepts. In addition competences for setting up, analysing and criticising modelling processes and the possible use of models is a formative aim in this own right for mathematics teaching in general education. The paper presents a theoretical...

  5. Spherical models

    CERN Document Server

    Wenninger, Magnus J

    2012-01-01

    Well-illustrated, practical approach to creating star-faced spherical forms that can serve as basic structures for geodesic domes. Complete instructions for making models from circular bands of paper with just a ruler and compass. Discusses tessellation, or tiling, and how to make spherical models of the semiregular solids and concludes with a discussion of the relationship of polyhedra to geodesic domes and directions for building models of domes. "". . . very pleasant reading."" - Science. 1979 edition.

  6. Zeebrugge Model

    DEFF Research Database (Denmark)

    Liu, Zhou; Frigaard, Peter

    This report presents the model on wave run-up and run-down on the Zeebrugge breakwater under short-crested oblique wave attacks. The model test was performed in March-April 2000 at the Hydraulics & Coastal Engineering Laboratory, Aalborg University.......This report presents the model on wave run-up and run-down on the Zeebrugge breakwater under short-crested oblique wave attacks. The model test was performed in March-April 2000 at the Hydraulics & Coastal Engineering Laboratory, Aalborg University....

  7. Stream Modelling

    DEFF Research Database (Denmark)

    Vestergaard, Kristian

    the engineers, but as the scale and the complexity of the hydraulic works increased, the mathematical models became so complex that a mathematical solution could not be obtained. This created a demand for new methods and again the experimental investigation became popular, but this time as measurements on small......-scale models. But still the scale and complexity of hydraulic works were increasing, and soon even small-scale models reached a natural limit for some applications. In the mean time the modern computer was developed, and it became possible to solve complex mathematical models by use of computer-based numerical...

  8. On the Nature of Severe Orographic Thunderstorms near the Andes in Subtropical South America

    Science.gov (United States)

    Rasmussen, Kristen Lani Emi

    worse in storms with significant mixed phase hydrometeors, such as graupel and hail, that are similarly affected by assumptions in the TRMM PR algorithm (Rasmussen et al. 2013). A quantitative approach that mitigates this bias using TRMM PR data was developed and employed to investigate the role of the most extreme precipitating systems on the hydrological cycle in South America (Rasmussen et al. 2014c). Results from this study indicate that ~95% of the accumulated warm season precipitation in La Plata Basin in subtropical South America is contributed by echoes structurally related to MCSs and their life cycle. From a hydrologic and climatological viewpoint, this empirical knowledge is critical, as the type of runoff and flooding that may occur depends on the specific character of the convective storm and precipitation reaching the surface, and has broad implications for the hydrological cycle in this region. Numerical simulations conducted with the NCAR Weather Research and Forecasting (WRF) model extends the observational analysis and provides an objective dynamical evaluation of storm initiation, development mechanisms, dynamics (Rasmussen and Houze 2014), and microphysics (Rasmussen et al. 2014d). The capping inversion in the lee of the Andes (Rasmussen and Houze 2011) is important in preventing premature triggering in the simulations. The impingement of the South American Low Level Jet on foothills and low mountains to the east of the main Andes range triggers extremely deep and intense convection. The simulated mesoscale systems closely resemble the storm structures seen by the TRMM satellite as well as the overall shape and character of the storms shown in GOES satellite data (Rasmussen and Houze 2014; Rasmussen et al. 2014d). Sensitivity studies removing and/or reducing various topographic features have shown the profound influence of the terrain on the initiation and upscale growth of the subsequent MCSs. The extreme vertical extent of the Andes tends to keep

  9. Ventilation Model

    Energy Technology Data Exchange (ETDEWEB)

    V. Chipman

    2002-10-05

    The purpose of the Ventilation Model is to simulate the heat transfer processes in and around waste emplacement drifts during periods of forced ventilation. The model evaluates the effects of emplacement drift ventilation on the thermal conditions in the emplacement drifts and surrounding rock mass, and calculates the heat removal by ventilation as a measure of the viability of ventilation to delay the onset of peak repository temperature and reduce its magnitude. The heat removal by ventilation is temporally and spatially dependent, and is expressed as the fraction of heat carried away by the ventilation air compared to the fraction of heat produced by radionuclide decay. One minus the heat removal is called the wall heat fraction, or the remaining amount of heat that is transferred via conduction to the surrounding rock mass. Downstream models, such as the ''Multiscale Thermohydrologic Model'' (BSC 2001), use the wall heat fractions as outputted from the Ventilation Model to initialize their post-closure analyses. The Ventilation Model report was initially developed to analyze the effects of preclosure continuous ventilation in the Engineered Barrier System (EBS) emplacement drifts, and to provide heat removal data to support EBS design. Revision 00 of the Ventilation Model included documentation of the modeling results from the ANSYS-based heat transfer model. The purposes of Revision 01 of the Ventilation Model are: (1) To validate the conceptual model for preclosure ventilation of emplacement drifts and verify its numerical application in accordance with new procedural requirements as outlined in AP-SIII-10Q, Models (Section 7.0). (2) To satisfy technical issues posed in KTI agreement RDTME 3.14 (Reamer and Williams 2001a). Specifically to demonstrate, with respect to the ANSYS ventilation model, the adequacy of the discretization (Section 6.2.3.1), and the downstream applicability of the model results (i.e. wall heat fractions) to

  10. Modeling Documents with Event Model

    Directory of Open Access Journals (Sweden)

    Longhui Wang

    2015-08-01

    Full Text Available Currently deep learning has made great breakthroughs in visual and speech processing, mainly because it draws lessons from the hierarchical mode that brain deals with images and speech. In the field of NLP, a topic model is one of the important ways for modeling documents. Topic models are built on a generative model that clearly does not match the way humans write. In this paper, we propose Event Model, which is unsupervised and based on the language processing mechanism of neurolinguistics, to model documents. In Event Model, documents are descriptions of concrete or abstract events seen, heard, or sensed by people and words are objects in the events. Event Model has two stages: word learning and dimensionality reduction. Word learning is to learn semantics of words based on deep learning. Dimensionality reduction is the process that representing a document as a low dimensional vector by a linear mode that is completely different from topic models. Event Model achieves state-of-the-art results on document retrieval tasks.

  11. Model Selection for Geostatistical Models

    Energy Technology Data Exchange (ETDEWEB)

    Hoeting, Jennifer A.; Davis, Richard A.; Merton, Andrew A.; Thompson, Sandra E.

    2006-02-01

    We consider the problem of model selection for geospatial data. Spatial correlation is typically ignored in the selection of explanatory variables and this can influence model selection results. For example, the inclusion or exclusion of particular explanatory variables may not be apparent when spatial correlation is ignored. To address this problem, we consider the Akaike Information Criterion (AIC) as applied to a geostatistical model. We offer a heuristic derivation of the AIC in this context and provide simulation results that show that using AIC for a geostatistical model is superior to the often used approach of ignoring spatial correlation in the selection of explanatory variables. These ideas are further demonstrated via a model for lizard abundance. We also employ the principle of minimum description length (MDL) to variable selection for the geostatistical model. The effect of sampling design on the selection of explanatory covariates is also explored.

  12. Didactical modelling

    DEFF Research Database (Denmark)

    Højgaard, Tomas; Hansen, Rune

    2016-01-01

    The purpose of this paper is to introduce Didactical Modelling as a research methodology in mathematics education. We compare the methodology with other approaches and argue that Didactical Modelling has its own specificity. We discuss the methodological “why” and explain why we find it useful to...

  13. Didactical modelling

    OpenAIRE

    Højgaard, Tomas; Hansen, Rune

    2016-01-01

    The purpose of this paper is to introduce Didactical Modelling as a research methodology in mathematics education. We compare the methodology with other approaches and argue that Didactical Modelling has its own specificity. We discuss the methodological “why” and explain why we find it useful to construct this approach in mathematics education research.

  14. Animal models

    DEFF Research Database (Denmark)

    Gøtze, Jens Peter; Krentz, Andrew

    2014-01-01

    In this issue of Cardiovascular Endocrinology, we are proud to present a broad and dedicated spectrum of reviews on animal models in cardiovascular disease. The reviews cover most aspects of animal models in science from basic differences and similarities between small animals and the human...

  15. Martingale Model

    OpenAIRE

    Giandomenico, Rossano

    2006-01-01

    The model determines a stochastic continuous process as continuous limit of a stochastic discrete process so to show that the stochastic continuous process converges to the stochastic discrete process such that we can integrate it. Furthermore, the model determines the expected volatility and the expected mean so to show that the volatility and the mean are increasing function of the time.

  16. Dispersion Modeling.

    Science.gov (United States)

    Budiansky, Stephen

    1980-01-01

    This article discusses the need for more accurate and complete input data and field verification of the various models of air pollutant dispension. Consideration should be given to changing the form of air quality standards based on enhanced dispersion modeling techniques. (Author/RE)

  17. Education models

    NARCIS (Netherlands)

    Poortman, Sybilla; Sloep, Peter

    2006-01-01

    Educational models describes a case study on a complex learning object. Possibilities are investigated for using this learning object, which is based on a particular educational model, outside of its original context. Furthermore, this study provides advice that might lead to an increase in

  18. Battery Modeling

    NARCIS (Netherlands)

    Jongerden, M.R.; Haverkort, Boudewijn R.H.M.

    2008-01-01

    The use of mobile devices is often limited by the capacity of the employed batteries. The battery lifetime determines how long one can use a device. Battery modeling can help to predict, and possibly extend this lifetime. Many different battery models have been developed over the years. However,

  19. En fascinerende fortælling om det 20. århundredes musik

    DEFF Research Database (Denmark)

    Bonde, Lars Ole

    2011-01-01

    Anmeldelse af Karl Aage Rasmussen: Musik i det tyvende århundrede: En fortælling. Gyldendal 2011.......Anmeldelse af Karl Aage Rasmussen: Musik i det tyvende århundrede: En fortælling. Gyldendal 2011....

  20. Külas on NATO peasekretär

    Index Scriptorium Estoniae

    2012-01-01

    Balti riikides visiidil olev NATO peasekretär Anders Fogh Rasmussen külastas NATO küberkaitsekeskust ja tunnustas Eesti panust kaitseorganisatsiooni kübervõimekusse. Rasmussen pidas ka avaliku loengu Tallinna Ülikoolis

  1. Linguistic models and linguistic modeling.

    Science.gov (United States)

    Pedryez, W; Vasilakos, A V

    1999-01-01

    The study is concerned with a linguistic approach to the design of a new category of fuzzy (granular) models. In contrast to numerically driven identification techniques, we concentrate on budding meaningful linguistic labels (granules) in the space of experimental data and forming the ensuing model as a web of associations between such granules. As such models are designed at the level of information granules and generate results in the same granular rather than pure numeric format, we refer to them as linguistic models. Furthermore, as there are no detailed numeric estimation procedures involved in the construction of the linguistic models carried out in this way, their design mode can be viewed as that of a rapid prototyping. The underlying algorithm used in the development of the models utilizes an augmented version of the clustering technique (context-based clustering) that is centered around a notion of linguistic contexts-a collection of fuzzy sets or fuzzy relations defined in the data space (more precisely a space of input variables). The detailed design algorithm is provided and contrasted with the standard modeling approaches commonly encountered in the literature. The usefulness of the linguistic mode of system modeling is discussed and illustrated with the aid of numeric studies including both synthetic data as well as some time series dealing with modeling traffic intensity over a broadband telecommunication network.

  2. OSPREY Model

    Energy Technology Data Exchange (ETDEWEB)

    Veronica J. Rutledge

    2013-01-01

    The absence of industrial scale nuclear fuel reprocessing in the U.S. has precluded the necessary driver for developing the advanced simulation capability now prevalent in so many other countries. Thus, it is essential to model complex series of unit operations to simulate, understand, and predict inherent transient behavior and feedback loops. A capability of accurately simulating the dynamic behavior of advanced fuel cycle separation processes will provide substantial cost savings and many technical benefits. The specific fuel cycle separation process discussed in this report is the off-gas treatment system. The off-gas separation consists of a series of scrubbers and adsorption beds to capture constituents of interest. Dynamic models are being developed to simulate each unit operation involved so each unit operation can be used as a stand-alone model and in series with multiple others. Currently, an adsorption model has been developed within Multi-physics Object Oriented Simulation Environment (MOOSE) developed at the Idaho National Laboratory (INL). Off-gas Separation and REcoverY (OSPREY) models the adsorption of off-gas constituents for dispersed plug flow in a packed bed under non-isothermal and non-isobaric conditions. Inputs to the model include gas, sorbent, and column properties, equilibrium and kinetic data, and inlet conditions. The simulation outputs component concentrations along the column length as a function of time from which breakthrough data is obtained. The breakthrough data can be used to determine bed capacity, which in turn can be used to size columns. It also outputs temperature along the column length as a function of time and pressure drop along the column length. Experimental data and parameters were input into the adsorption model to develop models specific for krypton adsorption. The same can be done for iodine, xenon, and tritium. The model will be validated with experimental breakthrough curves. Customers will be given access to

  3. Model hydrographs

    Science.gov (United States)

    Mitchell, W.D.

    1972-01-01

    Model hydrographs are composed of pairs of dimensionless ratios, arrayed in tabular form, which, when modified by the appropriate values of rainfall exceed and by the time and areal characteristics of the drainage basin, satisfactorily represent the flood hydrograph for the basin. Model bydrographs are developed from a dimensionless translation hydrograph, having a time base of T hours and appropriately modified for storm duration by routing through reservoir storage, S=kOx. Models fall into two distinct classes: (1) those for which the value of x is unity and which have all the characteristics of true unit hydrographs and (2) those for which the value of x is other than unity and to which the unit-hydrograph principles of proportionality and superposition do not apply. Twenty-six families of linear models and eight families of nonlinear models in tabular form from the principal subject of this report. Supplemental discussions describe the development of the models and illustrate their application. Other sections of the report, supplemental to the tables, describe methods of determining the hydrograph characteristics, T, k, and x, both from observed hydrograph and from the physical characteristics of the drainage basin. Five illustrative examples of use show that the models, when properly converted to incorporate actual rainfall excess and the time and areal characteristics of the drainage basins, do indeed satisfactorily represent the observed flood hydrographs for the basins.

  4. Stereometric Modelling

    Science.gov (United States)

    Grimaldi, P.

    2012-07-01

    These mandatory guidelines are provided for preparation of papers accepted for publication in the series of Volumes of The The stereometric modelling means modelling achieved with : - the use of a pair of virtual cameras, with parallel axes and positioned at a mutual distance average of 1/10 of the distance camera-object (in practice the realization and use of a stereometric camera in the modeling program); - the shot visualization in two distinct windows - the stereoscopic viewing of the shot while modelling. Since the definition of "3D vision" is inaccurately referred to as the simple perspective of an object, it is required to add the word stereo so that "3D stereo vision " shall stand for "three-dimensional view" and ,therefore, measure the width, height and depth of the surveyed image. Thanks to the development of a stereo metric model , either real or virtual, through the "materialization", either real or virtual, of the optical-stereo metric model made visible with a stereoscope. It is feasible a continuous on line updating of the cultural heritage with the help of photogrammetry and stereometric modelling. The catalogue of the Architectonic Photogrammetry Laboratory of Politecnico di Bari is available on line at: http://rappresentazione.stereofot.it:591/StereoFot/FMPro?-db=StereoFot.fp5&-lay=Scheda&-format=cerca.htm&-view

  5. Modeling complexes of modeled proteins.

    Science.gov (United States)

    Anishchenko, Ivan; Kundrotas, Petras J; Vakser, Ilya A

    2017-03-01

    Structural characterization of proteins is essential for understanding life processes at the molecular level. However, only a fraction of known proteins have experimentally determined structures. This fraction is even smaller for protein-protein complexes. Thus, structural modeling of protein-protein interactions (docking) primarily has to rely on modeled structures of the individual proteins, which typically are less accurate than the experimentally determined ones. Such "double" modeling is the Grand Challenge of structural reconstruction of the interactome. Yet it remains so far largely untested in a systematic way. We present a comprehensive validation of template-based and free docking on a set of 165 complexes, where each protein model has six levels of structural accuracy, from 1 to 6 Å C(α) RMSD. Many template-based docking predictions fall into acceptable quality category, according to the CAPRI criteria, even for highly inaccurate proteins (5-6 Å RMSD), although the number of such models (and, consequently, the docking success rate) drops significantly for models with RMSD > 4 Å. The results show that the existing docking methodologies can be successfully applied to protein models with a broad range of structural accuracy, and the template-based docking is much less sensitive to inaccuracies of protein models than the free docking. Proteins 2017; 85:470-478. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  6. A Model for Math Modeling

    Science.gov (United States)

    Lin, Tony; Erfan, Sasan

    2016-01-01

    Mathematical modeling is an open-ended research subject where no definite answers exist for any problem. Math modeling enables thinking outside the box to connect different fields of studies together including statistics, algebra, calculus, matrices, programming and scientific writing. As an integral part of society, it is the foundation for many…

  7. Modelling survival

    DEFF Research Database (Denmark)

    Ashauer, Roman; Albert, Carlo; Augustine, Starrlight

    2016-01-01

    The General Unified Threshold model for Survival (GUTS) integrates previously published toxicokinetic-toxicodynamic models and estimates survival with explicitly defined assumptions. Importantly, GUTS accounts for time-variable exposure to the stressor. We performed three studies to test...... the ability of GUTS to predict survival of aquatic organisms across different pesticide exposure patterns, time scales and species. Firstly, using synthetic data, we identified experimental data requirements which allow for the estimation of all parameters of the GUTS proper model. Secondly, we assessed how...

  8. Modelling Constructs

    DEFF Research Database (Denmark)

    Kindler, Ekkart

    2009-01-01

    There are many different notations and formalisms for modelling business processes and workflows. These notations and formalisms have been introduced with different purposes and objectives. Later, influenced by other notations, comparisons with other tools, or by standardization efforts, these no...

  9. Linear Models

    CERN Document Server

    Searle, Shayle R

    2012-01-01

    This 1971 classic on linear models is once again available--as a Wiley Classics Library Edition. It features material that can be understood by any statistician who understands matrix algebra and basic statistical methods.

  10. Modeling Arcs

    CERN Document Server

    Insepov, Zeke; Veitzer, Seth; Mahalingam, Sudhakar

    2011-01-01

    Although vacuum arcs were first identified over 110 years ago, they are not yet well understood. We have since developed a model of breakdown and gradient limits that tries to explain, in a self-consistent way: arc triggering, plasma initiation, plasma evolution, surface damage and gra- dient limits. We use simple PIC codes for modeling plasmas, molecular dynamics for modeling surface breakdown, and surface damage, and mesoscale surface thermodynamics and finite element electrostatic codes for to evaluate surface properties. Since any given experiment seems to have more variables than data points, we have tried to consider a wide variety of arcing (rf structures, e beam welding, laser ablation, etc.) to help constrain the problem, and concentrate on common mechanisms. While the mechanisms can be comparatively simple, modeling can be challenging.

  11. Paleoclimate Modeling

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Computer simulations of past climate. Variables provided as model output are described by parameter keyword. In some cases the parameter keywords are a subset of all...

  12. Anchor Modeling

    Science.gov (United States)

    Regardt, Olle; Rönnbäck, Lars; Bergholtz, Maria; Johannesson, Paul; Wohed, Petia

    Maintaining and evolving data warehouses is a complex, error prone, and time consuming activity. The main reason for this state of affairs is that the environment of a data warehouse is in constant change, while the warehouse itself needs to provide a stable and consistent interface to information spanning extended periods of time. In this paper, we propose a modeling technique for data warehousing, called anchor modeling, that offers non-destructive extensibility mechanisms, thereby enabling robust and flexible management of changes in source systems. A key benefit of anchor modeling is that changes in a data warehouse environment only require extensions, not modifications, to the data warehouse. This ensures that existing data warehouse applications will remain unaffected by the evolution of the data warehouse, i.e. existing views and functions will not have to be modified as a result of changes in the warehouse model.

  13. Model theory

    CERN Document Server

    Hodges, Wilfrid

    1993-01-01

    An up-to-date and integrated introduction to model theory, designed to be used for graduate courses (for students who are familiar with first-order logic), and as a reference for more experienced logicians and mathematicians.

  14. Accelerated life models modeling and statistical analysis

    CERN Document Server

    Bagdonavicius, Vilijandas

    2001-01-01

    Failure Time DistributionsIntroductionParametric Classes of Failure Time DistributionsAccelerated Life ModelsIntroductionGeneralized Sedyakin's ModelAccelerated Failure Time ModelProportional Hazards ModelGeneralized Proportional Hazards ModelsGeneralized Additive and Additive-Multiplicative Hazards ModelsChanging Shape and Scale ModelsGeneralizationsModels Including Switch-Up and Cycling EffectsHeredity HypothesisSummaryAccelerated Degradation ModelsIntroductionDegradation ModelsModeling the Influence of Explanatory Varia

  15. Do stroke models model stroke?

    Directory of Open Access Journals (Sweden)

    Philipp Mergenthaler

    2012-11-01

    Full Text Available Stroke is one of the leading causes of death worldwide and the biggest reason for long-term disability. Basic research has formed the modern understanding of stroke pathophysiology, and has revealed important molecular, cellular and systemic mechanisms. However, despite decades of research, most translational stroke trials that aim to introduce basic research findings into clinical treatment strategies – most notably in the field of neuroprotection – have failed. Among other obstacles, poor methodological and statistical standards, negative publication bias, and incomplete preclinical testing have been proposed as ‘translational roadblocks’. In this article, we introduce the models commonly used in preclinical stroke research, discuss some of the causes of failed translational success and review potential remedies. We further introduce the concept of modeling ‘care’ of stroke patients, because current preclinical research models the disorder but does not model care or state-of-the-art clinical testing. Stringent statistical methods and controlled preclinical trials have been suggested to counteract weaknesses in preclinical research. We conclude that preclinical stroke research requires (1 appropriate modeling of the disorder, (2 appropriate modeling of the care of stroke patients and (3 an approach to preclinical testing that is similar to clinical testing, including Phase 3 randomized controlled preclinical trials as necessary additional steps before new therapies enter clinical testing.

  16. Persistent Modelling

    DEFF Research Database (Denmark)

    2012-01-01

    The relationship between representation and the represented is examined here through the notion of persistent modelling. This notion is not novel to the activity of architectural design if it is considered as describing a continued active and iterative engagement with design concerns – an evident...... characteristic of architectural practice. But the persistence in persistent modelling can also be understood to apply in other ways, reflecting and anticipating extended roles for representation. This book identifies three principle areas in which these extensions are becoming apparent within contemporary....... It also provides critical insight into the use of contemporary modelling tools and methods, together with an examination of the implications their use has within the territories of architectural design, realisation and experience....

  17. Mathematical modeling

    CERN Document Server

    Eck, Christof; Knabner, Peter

    2017-01-01

    Mathematical models are the decisive tool to explain and predict phenomena in the natural and engineering sciences. With this book readers will learn to derive mathematical models which help to understand real world phenomena. At the same time a wealth of important examples for the abstract concepts treated in the curriculum of mathematics degrees are given. An essential feature of this book is that mathematical structures are used as an ordering principle and not the fields of application. Methods from linear algebra, analysis and the theory of ordinary and partial differential equations are thoroughly introduced and applied in the modeling process. Examples of applications in the fields electrical networks, chemical reaction dynamics, population dynamics, fluid dynamics, elasticity theory and crystal growth are treated comprehensively.

  18. Inflatable Models

    Institute of Scientific and Technical Information of China (English)

    Ling Li; Vasily Volkov

    2006-01-01

    A physically-based model is presented for the simulation of a new type of deformable objects-inflatable objects, such as shaped balloons, which consist of pressurized air enclosed by an elastic surface. These objects have properties inherent in both 3D and 2D elastic bodies, as they demonstrate the behaviour of 3D shapes using 2D formulations. As there is no internal structure in them, their behaviour is substantially different from the behaviour of deformable solid objects. We use one of the few available models for deformable surfaces, and enhance it to include the forces of internal and external pressure. These pressure forces may also incorporate buoyancy forces, to allow objects filled with a low density gas to float in denser media. The obtained models demonstrate rich dynamic behaviour, such as bouncing, floating, deflation and inflation.

  19. Lens Model

    DEFF Research Database (Denmark)

    Nash, Ulrik William

    2014-01-01

    Firms consist of people who make decisions to achieve goals. How do these people develop the expectations which underpin the choices they make? The lens model provides one answer to this question. It was developed by cognitive psychologist Egon Brunswik (1952) to illustrate his theory of probabil......Firms consist of people who make decisions to achieve goals. How do these people develop the expectations which underpin the choices they make? The lens model provides one answer to this question. It was developed by cognitive psychologist Egon Brunswik (1952) to illustrate his theory...... of probabilistic functionalism, and concerns the environment and the mind, and adaptation by the latter to the former. This entry is about the lens model, and probabilistic functionalism more broadly. Focus will mostly be on firms and their employees, but, to fully appreciate the scope, we have to keep in mind...

  20. Lens Model

    DEFF Research Database (Denmark)

    Nash, Ulrik William

    2014-01-01

    Firms consist of people who make decisions to achieve goals. How do these people develop the expectations which underpin the choices they make? The lens model provides one answer to this question. It was developed by cognitive psychologist Egon Brunswik (1952) to illustrate his theory of probabil......Firms consist of people who make decisions to achieve goals. How do these people develop the expectations which underpin the choices they make? The lens model provides one answer to this question. It was developed by cognitive psychologist Egon Brunswik (1952) to illustrate his theory...

  1. Molecular modeling

    Directory of Open Access Journals (Sweden)

    Aarti Sharma

    2009-01-01

    Full Text Available The use of computational chemistry in the development of novel pharmaceuticals is becoming an increasingly important tool. In the past, drugs were simply screened for effectiveness. The recent advances in computing power and the exponential growth of the knowledge of protein structures have made it possible for organic compounds to be tailored to decrease the harmful side effects and increase the potency. This article provides a detailed description of the techniques employed in molecular modeling. Molecular modeling is a rapidly developing discipline, and has been supported by the dramatic improvements in computer hardware and software in recent years.

  2. Smashnova Model

    CERN Document Server

    Sivaram, C

    2007-01-01

    An alternate model for gamma ray bursts is suggested. For a white dwarf (WD) and neutron star (NS) very close binary system, the WD (close to Mch) can detonate due to tidal heating, leading to a SN. Material falling on to the NS at relativistic velocities can cause its collapse to a magnetar or quark star or black hole leading to a GRB. As the material smashes on to the NS, it is dubbed the Smashnova model. Here the SN is followed by a GRB. NS impacting a RG (or RSG) (like in Thorne-Zytkow objects) can also cause a SN outburst followed by a GRB. Other variations are explored.

  3. Modelling language

    CERN Document Server

    Cardey, Sylviane

    2013-01-01

    In response to the need for reliable results from natural language processing, this book presents an original way of decomposing a language(s) in a microscopic manner by means of intra/inter‑language norms and divergences, going progressively from languages as systems to the linguistic, mathematical and computational models, which being based on a constructive approach are inherently traceable. Languages are described with their elements aggregating or repelling each other to form viable interrelated micro‑systems. The abstract model, which contrary to the current state of the art works in int

  4. Building Models and Building Modelling

    DEFF Research Database (Denmark)

    Jørgensen, Kaj Asbjørn; Skauge, Jørn

    I rapportens indledende kapitel beskrives de primære begreber vedrørende bygningsmodeller og nogle fundamentale forhold vedrørende computerbaseret modulering bliver opstillet. Desuden bliver forskellen mellem tegneprogrammer og bygnings­model­lerings­programmer beskrevet. Vigtige aspekter om......­lering og bygningsmodeller. Det bliver understreget at modellering bør udføres på flere abstraktions­niveauer og i to dimensioner i den såkaldte modelleringsmatrix. Ud fra dette identificeres de primære faser af bygningsmodel­lering. Dernæst beskrives de basale karakteristika for bygningsmodeller. Heri...... inkluderes en præcisering af begreberne objektorienteret software og objektorienteret modeller. Det bliver fremhævet at begrebet objektbaseret modellering giver en tilstrækkelig og bedre forståelse. Endelig beskrives forestillingen om den ideale bygningsmodel som værende én samlet model, der anvendes gennem...

  5. Zeebrugge Model

    DEFF Research Database (Denmark)

    Jensen, Morten S.; Frigaard, Peter

    In the following, results from model tests with Zeebrugge breakwater are presented. The objective with these tests is partly to investigate the influence on wave run-up due to a changing waterlevel during a storm. Finally, the influence on wave run-up due to an introduced longshore current...

  6. Why Model?

    Directory of Open Access Journals (Sweden)

    Olaf eWolkenhauer

    2014-01-01

    Full Text Available Next generation sequencing technologies are bringing about a renaissance of mining approaches. A comprehensive picture of the genetic landscape of an individual patient will be useful, for example, to identify groups of patients that do or do not respond to certain therapies. The high expectations may however not be satisfied if the number of patient groups with similar characteristics is going to be very large. I therefore doubt that mining sequence data will give us an understanding of why and when therapies work. For understanding the mechanisms underlying diseases, an alternative approach is to model small networks in quantitative mechanistic detail, to elucidate the role of gene and proteins in dynamically changing the functioning of cells. Here an obvious critique is that these models consider too few components, compared to what might be relevant for any particular cell function. I show here that mining approaches and dynamical systems theory are two ends of a spectrum of methodologies to choose from. Drawing upon personal experience in numerous interdisciplinary collaborations, I provide guidance on how to model by discussing the question Why model?

  7. Why model?

    Science.gov (United States)

    Wolkenhauer, Olaf

    2014-01-01

    Next generation sequencing technologies are bringing about a renaissance of mining approaches. A comprehensive picture of the genetic landscape of an individual patient will be useful, for example, to identify groups of patients that do or do not respond to certain therapies. The high expectations may however not be satisfied if the number of patient groups with similar characteristics is going to be very large. I therefore doubt that mining sequence data will give us an understanding of why and when therapies work. For understanding the mechanisms underlying diseases, an alternative approach is to model small networks in quantitative mechanistic detail, to elucidate the role of gene and proteins in dynamically changing the functioning of cells. Here an obvious critique is that these models consider too few components, compared to what might be relevant for any particular cell function. I show here that mining approaches and dynamical systems theory are two ends of a spectrum of methodologies to choose from. Drawing upon personal experience in numerous interdisciplinary collaborations, I provide guidance on how to model by discussing the question "Why model?"

  8. Model CAPM

    OpenAIRE

    Burianová, Eva

    2008-01-01

    Cílem první části této bakalářské práce je - pomocí analýzy výchozích textů - teoretické shrnutí ekonomických modelů a teorií, na kterých model CAPM stojí: Markowitzův model teorie portfolia (analýza maximalizace očekávaného užitku a na něm založený model výběru optimálního portfolia), Tobina (rozšíření Markowitzova modelu ? rozdělení výběru optimálního portfolia do dvou fází; nejprve určení optimální kombinace rizikových instrumentů a následná alokace dostupného kapitálu mezi tuto optimální ...

  9. Transport modeling

    Institute of Scientific and Technical Information of China (English)

    R.E. Waltz

    2007-01-01

    @@ There has been remarkable progress during the past decade in understanding and modeling turbulent transport in tokamaks. With some exceptions the progress is derived from the huge increases in computational power and the ability to simulate tokamak turbulence with ever more fundamental and physically realistic dynamical equations, e.g.

  10. Painting models

    Science.gov (United States)

    Baart, F.; Donchyts, G.; van Dam, A.; Plieger, M.

    2015-12-01

    The emergence of interactive art has blurred the line between electronic, computer graphics and art. Here we apply this art form to numerical models. Here we show how the transformation of a numerical model into an interactive painting can both provide insights and solve real world problems. The cases that are used as an example include forensic reconstructions, dredging optimization, barrier design. The system can be fed using any source of time varying vector fields, such as hydrodynamic models. The cases used here, the Indian Ocean (HYCOM), the Wadden Sea (Delft3D Curvilinear), San Francisco Bay (3Di subgrid and Delft3D Flexible Mesh), show that the method used is suitable for different time and spatial scales. High resolution numerical models become interactive paintings by exchanging their velocity fields with a high resolution (>=1M cells) image based flow visualization that runs in a html5 compatible web browser. The image based flow visualization combines three images into a new image: the current image, a drawing, and a uv + mask field. The advection scheme that computes the resultant image is executed in the graphics card using WebGL, allowing for 1M grid cells at 60Hz performance on mediocre graphic cards. The software is provided as open source software. By using different sources for a drawing one can gain insight into several aspects of the velocity fields. These aspects include not only the commonly represented magnitude and direction, but also divergence, topology and turbulence .

  11. Modeling Muscles

    Science.gov (United States)

    Goodwyn, Lauren; Salm, Sarah

    2007-01-01

    Teaching the anatomy of the muscle system to high school students can be challenging. Students often learn about muscle anatomy by memorizing information from textbooks or by observing plastic, inflexible models. Although these mediums help students learn about muscle placement, the mediums do not facilitate understanding regarding integration of…

  12. Entrepreneurship Models.

    Science.gov (United States)

    Finger Lakes Regional Education Center for Economic Development, Mount Morris, NY.

    This guide describes seven model programs that were developed by the Finger Lakes Regional Center for Economic Development (New York) to meet the training needs of female and minority entrepreneurs to help their businesses survive and grow and to assist disabled and dislocated workers and youth in beginning small businesses. The first three models…

  13. Quality modelling

    NARCIS (Netherlands)

    Tijskens, L.M.M.

    2003-01-01

    For modelling product behaviour, with respect to quality for users and consumers, its essential to have at least a fundamental notion what quality really is, and which product properties determine the quality assigned by the consumer to a product. In other words: what is allowed and what is to be

  14. Criticality Model

    Energy Technology Data Exchange (ETDEWEB)

    A. Alsaed

    2004-09-14

    The ''Disposal Criticality Analysis Methodology Topical Report'' (YMP 2003) presents the methodology for evaluating potential criticality situations in the monitored geologic repository. As stated in the referenced Topical Report, the detailed methodology for performing the disposal criticality analyses will be documented in model reports. Many of the models developed in support of the Topical Report differ from the definition of models as given in the Office of Civilian Radioactive Waste Management procedure AP-SIII.10Q, ''Models'', in that they are procedural, rather than mathematical. These model reports document the detailed methodology necessary to implement the approach presented in the Disposal Criticality Analysis Methodology Topical Report and provide calculations utilizing the methodology. Thus, the governing procedure for this type of report is AP-3.12Q, ''Design Calculations and Analyses''. The ''Criticality Model'' is of this latter type, providing a process evaluating the criticality potential of in-package and external configurations. The purpose of this analysis is to layout the process for calculating the criticality potential for various in-package and external configurations and to calculate lower-bound tolerance limit (LBTL) values and determine range of applicability (ROA) parameters. The LBTL calculations and the ROA determinations are performed using selected benchmark experiments that are applicable to various waste forms and various in-package and external configurations. The waste forms considered in this calculation are pressurized water reactor (PWR), boiling water reactor (BWR), Fast Flux Test Facility (FFTF), Training Research Isotope General Atomic (TRIGA), Enrico Fermi, Shippingport pressurized water reactor, Shippingport light water breeder reactor (LWBR), N-Reactor, Melt and Dilute, and Fort Saint Vrain Reactor spent nuclear fuel (SNF). The scope of

  15. Experimental Investigation of the End Plate Instability in the Extension of Polymer Melts in a Filament Stretch Rheometer. P.-Y. Longin, H. K. Rasmussen, A. Bach and O. Hassager

    DEFF Research Database (Denmark)

    Rasmussen, Henrik Koblitz; Longin, Pierre-Yves; Bach, Anders

    2001-01-01

    We consider here a particular instability, an axis symmetry breaking meniscus instability, that occurs under certain conditions in the transient filament stretching apparatus near the endplates as the plates are separated. Spiegelberg and McKinley [1] investigated this instability development in ...

  16. Growth of non-axisymmetric disturbances of the free surface in the filament stretching rheometer: experiments and simulation. Bach, A.; Rasmussen, H.K.; Longin, P.-Y.; Hassager, O

    DEFF Research Database (Denmark)

    Rasmussen, Henrik Koblitz; Bach, Anders; Longin, Pierre-Yves

    2002-01-01

    A filament stretching rheometer has been equipped with a bottom plate with a number of equally distributed perturbations of the circular rim. The temporal development of the resulting disturbance of the meniscus is followed with video recording and with simulations. At high strain rates the surface...

  17. Experimental Investigation of the End Plate Instability in the Extension of Polymer Melts in a Filament Stretch Rheometer. P.-Y. Longin, H. K. Rasmussen, A. Bach and O. Hassager

    DEFF Research Database (Denmark)

    Rasmussen, Henrik Koblitz; Longin, Pierre-Yves; Bach, Anders

    2001-01-01

    We consider here a particular instability, an axis symmetry breaking meniscus instability, that occurs under certain conditions in the transient filament stretching apparatus near the endplates as the plates are separated. Spiegelberg and McKinley [1] investigated this instability development in ...

  18. Growth of non-axisymmetric disturbances of the free surface in the filament stretching rheometer: experiments and simulation. Bach, A.; Rasmussen, H.K.; Longin, P.-Y.; Hassager, O

    DEFF Research Database (Denmark)

    Rasmussen, Henrik Koblitz; Bach, Anders; Longin, Pierre-Yves

    2002-01-01

    A filament stretching rheometer has been equipped with a bottom plate with a number of equally distributed perturbations of the circular rim. The temporal development of the resulting disturbance of the meniscus is followed with video recording and with simulations. At high strain rates the surfa...

  19. Information Model for Product Modeling

    Institute of Scientific and Technical Information of China (English)

    焦国方; 刘慎权

    1992-01-01

    The Key problems in product modeling for integrated CAD ∥CAM systems are the information structures and representations of products.They are taking more and more important roles in engineering applications.With the investigation on engineering product information and from the viewpoint of industrial process,in this paper,the information models are proposed and the definitions of the framework of product information are given.And then,the integration and the consistence of product information are discussed by introucing the entity and its instance.As a summary,the information structures described in this paper have many advantage and natures helpful in engineering design.

  20. Building Models and Building Modelling

    DEFF Research Database (Denmark)

    Jørgensen, Kaj; Skauge, Jørn

    2008-01-01

    I rapportens indledende kapitel beskrives de primære begreber vedrørende bygningsmodeller og nogle fundamentale forhold vedrørende computerbaseret modulering bliver opstillet. Desuden bliver forskellen mellem tegneprogrammer og bygnings­model­lerings­programmer beskrevet. Vigtige aspekter om comp...

  1. Molecular Modelling

    Directory of Open Access Journals (Sweden)

    Aarti Sharma

    2009-12-01

    Full Text Available

    The use of computational chemistry in the development of novel pharmaceuticals is becoming an increasingly important
    tool. In the past, drugs were simply screened for effectiveness. The recent advances in computing power and
    the exponential growth of the knowledge of protein structures have made it possible for organic compounds to tailored to
    decrease harmful side effects and increase the potency. This article provides a detailed description of the techniques
    employed in molecular modeling. Molecular modelling is a rapidly developing discipline, and has been supported from
    the dramatic improvements in computer hardware and software in recent years.

  2. Cheating models

    DEFF Research Database (Denmark)

    Arnoldi, Jakob

    The article discusses the use of algorithmic models for so-called High Frequency Trading (HFT) in finance. HFT is controversial yet widespread in modern financial markets. It is a form of automated trading technology which critics among other things claim can lead to market manipulation. Drawing...... on two cases, this article shows that manipulation more likely happens in the reverse way, meaning that human traders attempt to make algorithms ‘make mistakes’ or ‘mislead’ algos. Thus, it is algorithmic models, not humans, that are manipulated. Such manipulation poses challenges for security exchanges....... The article analyses these challenges and argues that we witness a new post-social form of human-technology interaction that will lead to a reconfiguration of professional codes for financial trading....

  3. Acyclic models

    CERN Document Server

    Barr, Michael

    2002-01-01

    Acyclic models is a method heavily used to analyze and compare various homology and cohomology theories appearing in topology and algebra. This book is the first attempt to put together in a concise form this important technique and to include all the necessary background. It presents a brief introduction to category theory and homological algebra. The author then gives the background of the theory of differential modules and chain complexes over an abelian category to state the main acyclic models theorem, generalizing and systemizing the earlier material. This is then applied to various cohomology theories in algebra and topology. The volume could be used as a text for a course that combines homological algebra and algebraic topology. Required background includes a standard course in abstract algebra and some knowledge of topology. The volume contains many exercises. It is also suitable as a reference work for researchers.

  4. Nuclear Models

    Science.gov (United States)

    Fossión, Rubén

    2010-09-01

    The atomic nucleus is a typical example of a many-body problem. On the one hand, the number of nucleons (protons and neutrons) that constitute the nucleus is too large to allow for exact calculations. On the other hand, the number of constituent particles is too small for the individual nuclear excitation states to be explained by statistical methods. Another problem, particular for the atomic nucleus, is that the nucleon-nucleon (n-n) interaction is not one of the fundamental forces of Nature, and is hard to put in a single closed equation. The nucleon-nucleon interaction also behaves differently between two free nucleons (bare interaction) and between two nucleons in the nuclear medium (dressed interaction). Because of the above reasons, specific nuclear many-body models have been devised of which each one sheds light on some selected aspects of nuclear structure. Only combining the viewpoints of different models, a global insight of the atomic nucleus can be gained. In this chapter, we revise the the Nuclear Shell Model as an example of the microscopic approach, and the Collective Model as an example of the geometric approach. Finally, we study the statistical properties of nuclear spectra, basing on symmetry principles, to find out whether there is quantum chaos in the atomic nucleus. All three major approaches have been rewarded with the Nobel Prize of Physics. In the text, we will stress how each approach introduces its own series of approximations to reduce the prohibitingly large number of degrees of freedom of the full many-body problem to a smaller manageable number of effective degrees of freedom.

  5. Modelling Behaviour

    DEFF Research Database (Denmark)

    2015-01-01

    This book reflects and expands on the current trend in the building industry to understand, simulate and ultimately design buildings by taking into consideration the interlinked elements and forces that act on them. This approach overcomes the traditional, exclusive focus on building tasks, while....... The chapter authors were invited speakers at the 5th Symposium "Modelling Behaviour", which took place at the CITA in Copenhagen in September 2015....

  6. Modeling Minds

    DEFF Research Database (Denmark)

    Michael, John

    others' minds. Then (2), in order to bring to light some possible justifications, as well as hazards and criticisms of the methodology of looking time tests, I will take a closer look at the concept of folk psychology and will focus on the idea that folk psychology involves using oneself as a model...... of other people in order to predict and understand their behavior. Finally (3), I will discuss the historical location and significance of the emergence of looking time tests...

  7. Modeling biomembranes.

    Energy Technology Data Exchange (ETDEWEB)

    Plimpton, Steven James; Heffernan, Julieanne; Sasaki, Darryl Yoshio; Frischknecht, Amalie Lucile; Stevens, Mark Jackson; Frink, Laura J. Douglas

    2005-11-01

    Understanding the properties and behavior of biomembranes is fundamental to many biological processes and technologies. Microdomains in biomembranes or ''lipid rafts'' are now known to be an integral part of cell signaling, vesicle formation, fusion processes, protein trafficking, and viral and toxin infection processes. Understanding how microdomains form, how they depend on membrane constituents, and how they act not only has biological implications, but also will impact Sandia's effort in development of membranes that structurally adapt to their environment in a controlled manner. To provide such understanding, we created physically-based models of biomembranes. Molecular dynamics (MD) simulations and classical density functional theory (DFT) calculations using these models were applied to phenomena such as microdomain formation, membrane fusion, pattern formation, and protein insertion. Because lipid dynamics and self-organization in membranes occur on length and time scales beyond atomistic MD, we used coarse-grained models of double tail lipid molecules that spontaneously self-assemble into bilayers. DFT provided equilibrium information on membrane structure. Experimental work was performed to further help elucidate the fundamental membrane organization principles.

  8. Model Construct Based Enterprise Model Architecture and Its Modeling Approach

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    In order to support enterprise integration, a kind of model construct based enterprise model architecture and its modeling approach are studied in this paper. First, the structural makeup and internal relationships of enterprise model architecture are discussed. Then, the concept of reusable model construct (MC) which belongs to the control view and can help to derive other views is proposed. The modeling approach based on model construct consists of three steps, reference model architecture synthesis, enterprise model customization, system design and implementation. According to MC based modeling approach a case study with the background of one-kind-product machinery manufacturing enterprises is illustrated. It is shown that proposal model construct based enterprise model architecture and modeling approach are practical and efficient.

  9. DTN Modeling in OPNET Modeler

    Directory of Open Access Journals (Sweden)

    PAPAJ Jan

    2014-05-01

    Full Text Available Traditional wireless networks use the concept of the point-to-point forwarding inherited from reliable wired networks which seems to be not ideal for wireless environment. New emerging applications and networks operate mostly disconnected. So-called Delay-Tolerant networks (DTNs are receiving increasing attentions from both academia and industry. DTNs introduced a store-carry-and-forward concept solving the problem of intermittent connectivity. Behavior of such networks is verified by real models, computer simulation or combination of the both approaches. Computer simulation has become the primary and cost effective tool for evaluating the performance of the DTNs. OPNET modeler is our target simulation tool and we wanted to spread OPNET’s simulation opportunity towards DTN. We implemented bundle protocol to OPNET modeler allowing simulate cases based on bundle concept as epidemic forwarding which relies on flooding the network with messages and the forwarding algorithm based on the history of past encounters (PRoPHET. The implementation details will be provided in article.

  10. A Model

    Institute of Scientific and Technical Information of China (English)

    Liu Zhiyang

    2011-01-01

    Similar to ISO Technical Committees,SAC Technical Committees undertake the management and coordination of standard's development and amendments in various sectors in industry,playing the role as a bridge among enterprises,research institutions and the governmental standardization administration.How to fully play the essential role is the vital issue SAC has been committing to resolve.Among hundreds of SAC TCs,one stands out in knitting together those isolated,scattered,but highly competitive enterprises in the same industry with the "Standards" thread,and achieving remarkable results in promoting industry development with standardization.It sets a role model for other TCs.

  11. 亳白芍GAP示范基地环境质量的评价%Study on Environmental Quality of the GAP base of Paeonia lactiflora Pall.in Bozhou

    Institute of Scientific and Technical Information of China (English)

    俞年军; 金传山; 姚宗凡; 王韵琴; 李文军

    2004-01-01

    亳白芍为毛茛科植物芍药Paeonia lactiflora Pall.的干燥根,为安徽亳州地区的道地栽培药材,因质量好、产量大而著名。安徽济人药业有限公司在亳州市谯城区十八里镇建立了亳白芍GAP生产基地。现就亳白芍实验示范基地环境质量的研究结果报告如下。

  12. Muğla-Fethiye Yöresinde Doğal Yayılış Yapan Crataegus orientalis Pall. ex M.Bieb. Taksonlarının Uçucu Bileşenlerinin Belirlenmesi

    Directory of Open Access Journals (Sweden)

    Sevgin ÖZDERİN

    2015-03-01

    Full Text Available In this study, volatile components of C. orientalis subsp. orientalis and C. orientalis subsp. szovitsii which are belonging an important howthorn taxa for Turkey, was determined. Leaf and flower samples of plant taxa were collected from Muğla-Fethiye in 2012 and dried in room temperature for determining to volatile contents of howthorn taxa and these contents were determined by GC-MS As result of analyses, totally 53 volatile components belonging to C. orientalis subsp. orientalis and C. orientalis subsp. szovitsii taxa were determined. According to GC-MS results, most effective components were determined as 2-Hexenal (38,55%, 3-Hexenol (13,98%, Capronaldehyde (6,81% for C. orientalis subsp. orientalis and Propyl methyl ketone (26.60%, Butyraldehyde(9,37%, 2-Hexenal (6,55% in case C. orientalis subsp. szovitsii

  13. 叶底珠各部位中一叶荻碱和别一叶荻碱的含量测定%Content determination of securinine and allosecurinine from every section of Securinega suffruticosa(Pall.)Rehd.

    Institute of Scientific and Technical Information of China (English)

    吕海花; 李雪晴; 王冉冉; 徐凌川

    2016-01-01

    采用高效液相色谱法测定叶底珠中一叶荻碱和别一叶荻碱在各部位中的含量.结果表明,一叶获碱在各部位的质量分数w根皮>w细根>w枝干皮>w木部>w嫩叶芽(济南)>w枝叶>w根>w嫩叶芽(临沂).别一叶荻碱在各部位的质量分数w根皮>w细根>w木部>w枝干皮>w根>w嫩叶芽(临沂)>w嫩叶芽(济南)>w枝叶.本实验为叶底珠生药成分中一叶荻碱和别一叶荻碱的定性和定量测定提供了科学依据.

  14. Full sun-spay-cutting method of Rosa Davurica Pall ' twig cutting%全光雾喷法在刺玫果嫩枝扦插上的应用

    Institute of Scientific and Technical Information of China (English)

    周军方; 段进潮; 徐岩; 任跃英; 王远亮; 肖兴利; 王秀萍

    2011-01-01

    全光雾喷法扦插育苗是近几年应用较多的快速育苗技术,它具有生根快、繁殖率高的特点,是快速繁殖优良品种苗木的一条重要途径。笔者对刺玫果分别用普通扦插和全光雾喷法进行夏季嫩枝扦插试验,结果表明用浓度为2×10-5g/mL的IBA浸泡16小时处理的插穗使用全光雾插法生根率可高达96%。%Full sun-spay-cutting method is the most applied on rapid seedling technique in recent years, its characteristic takes root quickly and reproductive rate high. It is important way of good varieties 'rapid propagation. By using chemical treatments of IBA on twig cuttings under common cutting and the full sun-spay-cutting method for summer cuttings test .The results show that adopted full sun-spay-eutting method ,which was cutting stems in summer, dousing in 2×10-5g/mL IBA for 16 hours .The rooting rate could reach 96%.

  15. 超声提取白刺中总生物碱及大孔树脂纯化的工艺研究%Ultrasound extraction total alkaloids from Nitraria sibirica Pall and process research of macroporous resin purification

    Institute of Scientific and Technical Information of China (English)

    王玉玲; 曾会明; 张建秋; 马挺军

    2013-01-01

    为优化西伯利亚白刺种籽中总生物碱的提取工艺,采用超声波提取总碱,以硫酸阿托品为对照品,酸性染料比色法测定白刺中总生物碱的含量,探讨料液比、提取温度、时间、乙醇浓度4个因素的影响,确定最佳提取参数.从7种大孔吸附树脂中筛选出对白刺生物碱有最佳分离纯化效果的一种树脂,研究其对生物碱静态、动态吸附、解析效果.研究结果表明,当料液比为1∶20,温度60℃,时间40 min,乙醇浓度70%时,总生物碱提取率(生物碱/种籽重)最高,217.372 9 μg/g D101对白刺总生物碱的吸附、解析效果最好,对其进行动态吸附,可知最佳的工艺条件为上样液pH值为5,流速为0.75 mL/min,乙醇的洗脱浓度为80%.%In order to optimize the extract condition, total alkaloids in Nitraria sibirica was extracted by ultrasound and the content of total alkaloids was determined by the acidic dye colorimetry, the effects of solid-liquid ratio, temperature, time and ethanol concentration on the optimum extraction parameters were investigated, thereby determining the optimal extraction parameters; the best one of isolation and purification from seven kinds of resin were screened out to research its effects on the alkaloids of static, dynamic adsorption. The results show that with the conditions of solid-liquid ratio of 1:20, temperature 60 ℃, time 40 minutes, ethanol concentration of 70%, the highest total alkaloid extract rate was 217.372 9 μg/g; the adsorption and resolution effects of D101 on N. sibirica's total alkaloids were the best, the dynamic adsorption tests proved that the optimum process conditions were: sample solution pH 5, flow rate 0.75mL/min, ethanol concentration 80%.

  16. Effects of Harvest Stage on Ornamental Quality of Cut Flow ers of Herbaceous Peony (Paeonia lacti f lora Pall .)%采收期对芍药切花保鲜效果的影响

    Institute of Scientific and Technical Information of China (English)

    高水平; 魏春梅; 王焰; 吕明; 范丙友

    2013-01-01

    It is one of the most critical postharvest technologies to harvest cut herbaceous peony flowers at most suitable developmental stages .Using herbaceous peony cv .‘Xishimian’ as materi-als ,the effects of developmental stages on the vase life ,the opening life ,the flower diameter ,and the fresh weight loss rate were analyzed in order to ascertain the most suitable harvest stage for herbaceous peony .The result showed that the vase life and the opening life of cut herbaceous peo-ny flowers harvested at stage Ⅱ (Unfold-petal stage) were longer than at stages Ⅲ (Changing-color stage) and Ⅳ (Soft-bud stage) .Although the flower diameters of cut flower harvested at stage Ⅱ were smaller than at stages Ⅲ and Ⅳ ,the ornamental quality was not reduced signifi-cantly .Preservation solution (2% sucrose+200 mg/L 8-HQ+1 mol/L STS) had a good effect on flower diameter and reduced the fresh weight loss rate for herbaceous peony cv .‘Xishimian’ .%适期采收是芍药切花采后保鲜的关键技术。为确定芍药切花的最适采收期,以西施面芍药为材料,研究了采收期对芍药切花的瓶插寿命、开放寿命、切花花径、鲜质量损失率的影响。结果表明,Ⅱ级(松瓣期)采收的芍药切花瓶插寿命及开放寿命均优于Ⅲ(转色期)和Ⅳ级(暄蕾期)花,尽管切花花径略小于Ⅲ和Ⅳ级花,但其观赏价值并未明显降低;保鲜液(2%蔗糖+200 m g/L 8羟基喹啉+1 mol/L硫代硫酸银)对于增大切花花径、延缓并减少切花鲜质量损失具有一定促进作用。

  17. Modelling Behaviour

    DEFF Research Database (Denmark)

    2015-01-01

    This book reflects and expands on the current trend in the building industry to understand, simulate and ultimately design buildings by taking into consideration the interlinked elements and forces that act on them. This approach overcomes the traditional, exclusive focus on building tasks, while....... The chapter authors were invited speakers at the 5th Symposium "Modelling Behaviour", which took place at the CITA in Copenhagen in September 2015....... posing new challenges in all areas of the industry from material and structural to the urban scale. Contributions from invited experts, papers and case studies provide the reader with a comprehensive overview of the field, as well as perspectives from related disciplines, such as computer science...

  18. Econometric modelling

    Directory of Open Access Journals (Sweden)

    M. Alguacil Marí

    2017-08-01

    Full Text Available The current economic environment, together with the low scores obtained by our students in recent years, makes it necessary to incorporate new teaching methods. In this sense, econometric modelling provides a unique opportunity offering to the student with the basic tools to address the study of Econometrics in a deeper and novel way. In this article, this teaching method is described, presenting also an example based on a recent study carried out by two students of the Degree of Economics. Likewise, the success of this method is evaluated quantitatively in terms of academic performance. The results confirm our initial idea that the greater involvement of the student, as well as the need for a more complete knowledge of the subject, suppose a stimulus for the study of this subject. As evidence of this, we show how those students who opted for the method we propose here obtained higher qualifications than those that chose the traditional method.

  19. Modelling Defiguration

    DEFF Research Database (Denmark)

    Bork Petersen, Franziska

    2013-01-01

    For the presentation of his autumn/winter 2012 collection in Paris and subsequently in Copenhagen, Danish designer Henrik Vibskov installed a mobile catwalk. The article investigates the choreographic impact of this scenography on those who move through it. Drawing on Dance Studies, the analytical...... advantageous manner. Stepping on the catwalk’s sloping, moving surfaces decelerates the models’ walk and makes it cautious, hesitant and shaky: suddenly the models lack exactly the affirmative, staccato, striving quality of motion, and the condescending expression that they perform on most contemporary...... catwalks. Vibskov’s catwalk induces what the dance scholar Gabriele Brandstetter has labelled a ‘defigurative choregoraphy’: a straying from definitions, which exist in ballet as in other movement-based genres, of how a figure should move and appear (1998). The catwalk scenography in this instance...

  20. Application of the PE method to up-slope sound propagation

    DEFF Research Database (Denmark)

    Rasmussen, Karsten Bo; Arranz, Marta Galindo

    1995-01-01

    velocity at the surface. The staircase PE method approximates the normal at the slope surface with the vertical component at the stair-step surface. A numerical correction can be included. Using a scale model facility [K. B. Rasmussen, 3617–3620 (1994)], a series of measurements is carried out. The results......The wide-angle PE method is applied to the prediction of sound propagation in a range-dependent environment. The finite-difference model treats the sloping ground by a staircase approximation. The method allows impedance and slope angle variations to be taken into account. The implementation...

  1. The solar flux influence on quiet time conductances in the auroral ionosphere

    Energy Technology Data Exchange (ETDEWEB)

    Moen, J. (Univ. of Oslo (Norway)); Brekke, A. (Univ. of Tromso (Norway))

    1993-05-21

    The authors report on measurements of the Hall and Pedersen conductances of the quiet time auroral ionosphere made using the EISCAT radar. They derive expressions for the conductances as a function of the 10.7cm solar flux (S[sub a]) between 70 and 250 ([times]10[sup [minus]22]Wm[sup [minus]2]Hz[sup [minus]1]), and the solar zenith angle [chi]. The results are consistent with the recent model results of Rasmussen et al, but at higher levels of solar activity give results higher than previous models.

  2. A straightforward methodology for designing continuous monoclonal antibody capture multi-column chromatography processes.

    Science.gov (United States)

    Gjoka, Xhorxhi; Rogler, Karl; Martino, Richard Alexander; Gantier, Rene; Schofield, Mark

    2015-10-16

    A simple process development strategy for continuous capture multi-column chromatography (MCC) is described. The approach involves a few single column breakthrough experiments, based on several simplifying observations that enable users to rapidly convert batch processes into well-designed multi-column processes. The method was validated using a BioSMB(®) (Pall Life Sciences) lab scale multi-column system and a mAb capture process employing Protein A resin. The approach enables users to optimize MCC processes based on their internal preferences and constraints without requiring any mathematical modeling expertise.

  3. On Activity modelling in process modeling

    Directory of Open Access Journals (Sweden)

    Dorel Aiordachioaie

    2001-12-01

    Full Text Available The paper is looking to the dynamic feature of the meta-models of the process modelling process, the time. Some principles are considered and discussed as main dimensions of any modelling activity: the compatibility of the substances, the equipresence of phenomena and the solvability of the model. The activity models are considered and represented at meta-level.

  4. Towards a Multi Business Model Innovation Model

    DEFF Research Database (Denmark)

    Lindgren, Peter; Jørgensen, Rasmus

    2012-01-01

    This paper studies the evolution of business model (BM) innovations related to a multi business model framework. The paper tries to answer the research questions: • What are the requirements for a multi business model innovation model (BMIM)? • How should a multi business model innovation model...... look like? Different generations of BMIMs are initially studied in the context of laying the baseline for how next generation multi BM Innovation model (BMIM) should look like. All generations of models are analyzed with the purpose of comparing the characteristics and challenges of previous...

  5. Better Language Models with Model Merging

    CERN Document Server

    Brants, T

    1996-01-01

    This paper investigates model merging, a technique for deriving Markov models from text or speech corpora. Models are derived by starting with a large and specific model and by successively combining states to build smaller and more general models. We present methods to reduce the time complexity of the algorithm and report on experiments on deriving language models for a speech recognition task. The experiments show the advantage of model merging over the standard bigram approach. The merged model assigns a lower perplexity to the test set and uses considerably fewer states.

  6. Model Selection Principles in Misspecified Models

    CERN Document Server

    Lv, Jinchi

    2010-01-01

    Model selection is of fundamental importance to high dimensional modeling featured in many contemporary applications. Classical principles of model selection include the Kullback-Leibler divergence principle and the Bayesian principle, which lead to the Akaike information criterion and Bayesian information criterion when models are correctly specified. Yet model misspecification is unavoidable when we have no knowledge of the true model or when we have the correct family of distributions but miss some true predictor. In this paper, we propose a family of semi-Bayesian principles for model selection in misspecified models, which combine the strengths of the two well-known principles. We derive asymptotic expansions of the semi-Bayesian principles in misspecified generalized linear models, which give the new semi-Bayesian information criteria (SIC). A specific form of SIC admits a natural decomposition into the negative maximum quasi-log-likelihood, a penalty on model dimensionality, and a penalty on model miss...

  7. The IMACLIM model; Le modele IMACLIM

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-07-01

    This document provides annexes to the IMACLIM model which propose an actualized description of IMACLIM, model allowing the design of an evaluation tool of the greenhouse gases reduction policies. The model is described in a version coupled with the POLES, technical and economical model of the energy industry. Notations, equations, sources, processing and specifications are proposed and detailed. (A.L.B.)

  8. Building Mental Models by Dissecting Physical Models

    Science.gov (United States)

    Srivastava, Anveshna

    2016-01-01

    When students build physical models from prefabricated components to learn about model systems, there is an implicit trade-off between the physical degrees of freedom in building the model and the intensity of instructor supervision needed. Models that are too flexible, permitting multiple possible constructions require greater supervision to…

  9. The IMACLIM model; Le modele IMACLIM

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-07-01

    This document provides annexes to the IMACLIM model which propose an actualized description of IMACLIM, model allowing the design of an evaluation tool of the greenhouse gases reduction policies. The model is described in a version coupled with the POLES, technical and economical model of the energy industry. Notations, equations, sources, processing and specifications are proposed and detailed. (A.L.B.)

  10. Modelling live forensic acquisition

    CSIR Research Space (South Africa)

    Grobler, MM

    2009-06-01

    Full Text Available This paper discusses the development of a South African model for Live Forensic Acquisition - Liforac. The Liforac model is a comprehensive model that presents a range of aspects related to Live Forensic Acquisition. The model provides forensic...

  11. Continuous Time Model Estimation

    OpenAIRE

    Carl Chiarella; Shenhuai Gao

    2004-01-01

    This paper introduces an easy to follow method for continuous time model estimation. It serves as an introduction on how to convert a state space model from continuous time to discrete time, how to decompose a hybrid stochastic model into a trend model plus a noise model, how to estimate the trend model by simulation, and how to calculate standard errors from estimation of the noise model. It also discusses the numerical difficulties involved in discrete time models that bring about the unit ...

  12. Chilled Ammonia Process for CO2 Capture

    DEFF Research Database (Denmark)

    Darde, Victor Camille Alfred; Thomsen, Kaj; Well, Willy J.M. van

    2010-01-01

    The chilled ammonia process absorbs the CO2 at low temperature (2–10°C). The heat of absorption of carbon dioxide by ammonia is significantly lower than for amines. In addition, degradation problems can be avoided and a high carbon dioxide capacity is achieved. Hence, this process shows good...... perspectives for decreasing the heat requirement. However, a scientific understanding of the processes is required. The thermodynamic properties of the NH3–CO2–H2O system were described using the extended UNIQUAC electrolyte model developed by Thomsen and Rasmussen in a temperature range from 0 to 110°C...

  13. Commentary

    DEFF Research Database (Denmark)

    Rasmussen, Jens

    1993-01-01

    basically to understand the cognitive process and cooperative patterns of the actors in work, and to develop a framework for design of advanced information systems. The work contributed to a CEC basic research action project; MOHAWC; modeling human activities in work context (Rasmussen et al., 1991...... in the research paradigms than to extend the scope of the human factors profession to encompass total socio-technical systems. This conclusion is not in contradiction to the arguments in the articles reviewed, but calls for a substantial extension....

  14. Comparative Protein Structure Modeling Using MODELLER.

    Science.gov (United States)

    Webb, Benjamin; Sali, Andrej

    2016-06-20

    Comparative protein structure modeling predicts the three-dimensional structure of a given protein sequence (target) based primarily on its alignment to one or more proteins of known structure (templates). The prediction process consists of fold assignment, target-template alignment, model building, and model evaluation. This unit describes how to calculate comparative models using the program MODELLER and how to use the ModBase database of such models, and discusses all four steps of comparative modeling, frequently observed errors, and some applications. Modeling lactate dehydrogenase from Trichomonas vaginalis (TvLDH) is described as an example. The download and installation of the MODELLER software is also described. © 2016 by John Wiley & Sons, Inc.

  15. Concept Modeling vs. Data modeling in Practice

    DEFF Research Database (Denmark)

    Madsen, Bodil Nistrup; Erdman Thomsen, Hanne

    2015-01-01

    account of the inheritance of characteristics and allows us to introduce a number of principles and constraints which render concept modeling more coherent than earlier approaches. Second, we explain how terminological ontologies can be used as the basis for developing conceptual and logical data models......This chapter shows the usefulness of terminological concept modeling as a first step in data modeling. First, we introduce terminological concept modeling with terminological ontologies, i.e. concept systems enriched with characteristics modeled as feature specifications. This enables a formal...

  16. Business Model Innovation

    OpenAIRE

    Dodgson, Mark; Gann, David; Phillips, Nelson; Massa, Lorenzo; Tucci, Christopher

    2014-01-01

    The chapter offers a broad review of the literature at the nexus between Business Models and innovation studies, and examines the notion of Business Model Innovation in three different situations: Business Model Design in newly formed organizations, Business Model Reconfiguration in incumbent firms, and Business Model Innovation in the broad context of sustainability. Tools and perspectives to make sense of Business Models and support managers and entrepreneurs in dealing with Business Model ...

  17. Modeling cholera outbreaks.

    Science.gov (United States)

    Chao, Dennis L; Longini, Ira M; Morris, J Glenn

    2014-01-01

    Mathematical modeling can be a valuable tool for studying infectious disease outbreak dynamics and simulating the effects of possible interventions. Here, we describe approaches to modeling cholera outbreaks and how models have been applied to explore intervention strategies, particularly in Haiti. Mathematical models can play an important role in formulating and evaluating complex cholera outbreak response options. Major challenges to cholera modeling are insufficient data for calibrating models and the need to tailor models for different outbreak scenarios.

  18. Modeling cholera outbreaks

    Science.gov (United States)

    Longini, Ira M.; Morris, J. Glenn

    2014-01-01

    Mathematical modeling can be a valuable tool for studying infectious disease outbreak dynamics and simulating the effects of possible interventions. Here, we describe approaches to modeling cholera outbreaks and how models have been applied to explore intervention strategies, particularly in Haiti. Mathematical models can play an important role in formulating and evaluating complex cholera outbreak response options. Major challenges to cholera modeling are insufficient data for calibrating models and the need to tailor models for different outbreak scenarios. PMID:23412687

  19. Model Manipulation for End-User Modelers

    DEFF Research Database (Denmark)

    Acretoaie, Vlad

    of these proposals. To achieve its first goal, the thesis presents the findings of a Systematic Mapping Study showing that human factors topics are scarcely and relatively poorly addressed in model transformation research. Motivated by these findings, the thesis explores the requirements of end-user modelers......End-user modelers are domain experts who create and use models as part of their work. They are typically not Software Engineers, and have little or no programming and meta-modeling experience. However, using model manipulation languages developed in the context of Model-Driven Engineering often...... requires such experience. These languages are therefore only used by a small subset of the modelers that could, in theory, benefit from them. The goals of this thesis are to substantiate this observation, introduce the concepts and tools required to overcome it, and provide empirical evidence in support...

  20. Air Quality Dispersion Modeling - Alternative Models

    Science.gov (United States)

    Models, not listed in Appendix W, that can be used in regulatory applications with case-by-case justification to the Reviewing Authority as noted in Section 3.2, Use of Alternative Models, in Appendix W.

  1. From Product Models to Product State Models

    DEFF Research Database (Denmark)

    Larsen, Michael Holm

    1999-01-01

    A well-known technology designed to handle product data is Product Models. Product Models are in their current form not able to handle all types of product state information. Hence, the concept of a Product State Model (PSM) is proposed. The PSM and in particular how to model a PSM is the Research...... Object for this project. In the presentation, benefits and challenges of the PSM will be presented as a basis for the discussion....

  2. Measurement and Modeling: Infectious Disease Modeling

    NARCIS (Netherlands)

    Kretzschmar, MEE

    2016-01-01

    After some historical remarks about the development of mathematical theory for infectious disease dynamics we introduce a basic mathematical model for the spread of an infection with immunity. The concepts of the model are explained and the model equations are derived from first principles. Using th

  3. Modelling of Hydraulic Robot

    DEFF Research Database (Denmark)

    Madsen, Henrik; Zhou, Jianjun; Hansen, Lars Henrik

    1997-01-01

    This paper describes a case study of identifying the physical model (or the grey box model) of a hydraulic test robot. The obtained model is intended to provide a basis for model-based control of the robot. The physical model is formulated in continuous time and is derived by application...... of the laws of physics on the system. The unknown (or uncertain) parameters are estimated with Maximum Likelihood (ML) parameter estimation. The identified model has been evaluated by comparing the measurements with simulation of the model. The identified model was much more capable of describing the dynamics...... of the system than the deterministic model....

  4. Product and Process Modelling

    DEFF Research Database (Denmark)

    Cameron, Ian T.; Gani, Rafiqul

    This book covers the area of product and process modelling via a case study approach. It addresses a wide range of modelling applications with emphasis on modelling methodology and the subsequent in-depth analysis of mathematical models to gain insight via structural aspects of the models. These ...

  5. "Bohr's Atomic Model."

    Science.gov (United States)

    Willden, Jeff

    2001-01-01

    "Bohr's Atomic Model" is a small interactive multimedia program that introduces the viewer to a simplified model of the atom. This interactive simulation lets students build an atom using an atomic construction set. The underlying design methodology for "Bohr's Atomic Model" is model-centered instruction, which means the central model of the…

  6. Modelling of Hydraulic Robot

    DEFF Research Database (Denmark)

    Madsen, Henrik; Zhou, Jianjun; Hansen, Lars Henrik

    1997-01-01

    This paper describes a case study of identifying the physical model (or the grey box model) of a hydraulic test robot. The obtained model is intended to provide a basis for model-based control of the robot. The physical model is formulated in continuous time and is derived by application...

  7. Forest-fire models

    Science.gov (United States)

    Haiganoush Preisler; Alan Ager

    2013-01-01

    For applied mathematicians forest fire models refer mainly to a non-linear dynamic system often used to simulate spread of fire. For forest managers forest fire models may pertain to any of the three phases of fire management: prefire planning (fire risk models), fire suppression (fire behavior models), and postfire evaluation (fire effects and economic models). In...

  8. Solicited abstract: Global hydrological modeling and models

    Science.gov (United States)

    Xu, Chong-Yu

    2010-05-01

    The origins of rainfall-runoff modeling in the broad sense can be found in the middle of the 19th century arising in response to three types of engineering problems: (1) urban sewer design, (2) land reclamation drainage systems design, and (3) reservoir spillway design. Since then numerous empirical, conceptual and physically-based models are developed including event based models using unit hydrograph concept, Nash's linear reservoir models, HBV model, TOPMODEL, SHE model, etc. From the late 1980s, the evolution of global and continental-scale hydrology has placed new demands on hydrologic modellers. The macro-scale hydrological (global and regional scale) models were developed on the basis of the following motivations (Arenll, 1999). First, for a variety of operational and planning purposes, water resource managers responsible for large regions need to estimate the spatial variability of resources over large areas, at a spatial resolution finer than can be provided by observed data alone. Second, hydrologists and water managers are interested in the effects of land-use and climate variability and change over a large geographic domain. Third, there is an increasing need of using hydrologic models as a base to estimate point and non-point sources of pollution loading to streams. Fourth, hydrologists and atmospheric modellers have perceived weaknesses in the representation of hydrological processes in regional and global climate models, and developed global hydrological models to overcome the weaknesses of global climate models. Considerable progress in the development and application of global hydrological models has been achieved to date, however, large uncertainties still exist considering the model structure including large scale flow routing, parameterization, input data, etc. This presentation will focus on the global hydrological models, and the discussion includes (1) types of global hydrological models, (2) procedure of global hydrological model development

  9. Bayesian Model Selection and Statistical Modeling

    CERN Document Server

    Ando, Tomohiro

    2010-01-01

    Bayesian model selection is a fundamental part of the Bayesian statistical modeling process. The quality of these solutions usually depends on the goodness of the constructed Bayesian model. Realizing how crucial this issue is, many researchers and practitioners have been extensively investigating the Bayesian model selection problem. This book provides comprehensive explanations of the concepts and derivations of the Bayesian approach for model selection and related criteria, including the Bayes factor, the Bayesian information criterion (BIC), the generalized BIC, and the pseudo marginal lik

  10. From Numeric Models to Granular System Modeling

    Directory of Open Access Journals (Sweden)

    Witold Pedrycz

    2015-03-01

    To make this study self-contained, we briefly recall the key concepts of granular computing and demonstrate how this conceptual framework and its algorithmic fundamentals give rise to granular models. We discuss several representative formal setups used in describing and processing information granules including fuzzy sets, rough sets, and interval calculus. Key architectures of models dwell upon relationships among information granules. We demonstrate how information granularity and its optimization can be regarded as an important design asset to be exploited in system modeling and giving rise to granular models. With this regard, an important category of rule-based models along with their granular enrichments is studied in detail.

  11. Geologic Framework Model Analysis Model Report

    Energy Technology Data Exchange (ETDEWEB)

    R. Clayton

    2000-12-19

    The purpose of this report is to document the Geologic Framework Model (GFM), Version 3.1 (GFM3.1) with regard to data input, modeling methods, assumptions, uncertainties, limitations, and validation of the model results, qualification status of the model, and the differences between Version 3.1 and previous versions. The GFM represents a three-dimensional interpretation of the stratigraphy and structural features of the location of the potential Yucca Mountain radioactive waste repository. The GFM encompasses an area of 65 square miles (170 square kilometers) and a volume of 185 cubic miles (771 cubic kilometers). The boundaries of the GFM were chosen to encompass the most widely distributed set of exploratory boreholes (the Water Table or WT series) and to provide a geologic framework over the area of interest for hydrologic flow and radionuclide transport modeling through the unsaturated zone (UZ). The depth of the model is constrained by the inferred depth of the Tertiary-Paleozoic unconformity. The GFM was constructed from geologic map and borehole data. Additional information from measured stratigraphy sections, gravity profiles, and seismic profiles was also considered. This interim change notice (ICN) was prepared in accordance with the Technical Work Plan for the Integrated Site Model Process Model Report Revision 01 (CRWMS M&O 2000). The constraints, caveats, and limitations associated with this model are discussed in the appropriate text sections that follow. The GFM is one component of the Integrated Site Model (ISM) (Figure l), which has been developed to provide a consistent volumetric portrayal of the rock layers, rock properties, and mineralogy of the Yucca Mountain site. The ISM consists of three components: (1) Geologic Framework Model (GFM); (2) Rock Properties Model (RPM); and (3) Mineralogic Model (MM). The ISM merges the detailed project stratigraphy into model stratigraphic units that are most useful for the primary downstream models and the

  12. Model Theory and Applications

    CERN Document Server

    Mangani, P

    2011-01-01

    This title includes: Lectures - G.E. Sacks - Model theory and applications, and H.J. Keisler - Constructions in model theory; and, Seminars - M. Servi - SH formulas and generalized exponential, and J.A. Makowski - Topological model theory.

  13. Wildfire Risk Main Model

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — The model combines three modeled fire behavior parameters (rate of spread, flame length, crown fire potential) and one modeled ecological health measure (fire regime...

  14. Energy modelling software

    CSIR Research Space (South Africa)

    Osburn, L

    2010-01-01

    Full Text Available The construction industry has turned to energy modelling in order to assist them in reducing the amount of energy consumed by buildings. However, while the energy loads of buildings can be accurately modelled, energy models often under...

  15. Taxonomy Icon Data: Polysphondylium pallidum [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available Polysphondylium pallidum Polysphondylium pallidum Polysphondylium_pallidum_L.png Polysphondylium_pall...idum_NL.png Polysphondylium_pallidum_S.png Polysphondylium_pallidum_NS.png http://bioscien...cedbc.jp/taxonomy_icon/icon.cgi?i=Polysphondylium+pallidum&t=L http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Polysphondylium+pall...idum&t=NL http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Polysphondylium+pall...idum&t=S http://biosciencedbc.jp/taxonomy_icon/icon.cgi?i=Polysphondylium+pallidum&t=N

  16. Computational neurogenetic modeling

    CERN Document Server

    Benuskova, Lubica

    2010-01-01

    Computational Neurogenetic Modeling is a student text, introducing the scope and problems of a new scientific discipline - Computational Neurogenetic Modeling (CNGM). CNGM is concerned with the study and development of dynamic neuronal models for modeling brain functions with respect to genes and dynamic interactions between genes. These include neural network models and their integration with gene network models. This new area brings together knowledge from various scientific disciplines, such as computer and information science, neuroscience and cognitive science, genetics and molecular biol

  17. Predictive Models for Music

    OpenAIRE

    Paiement, Jean-François; Grandvalet, Yves; Bengio, Samy

    2008-01-01

    Modeling long-term dependencies in time series has proved very difficult to achieve with traditional machine learning methods. This problem occurs when considering music data. In this paper, we introduce generative models for melodies. We decompose melodic modeling into two subtasks. We first propose a rhythm model based on the distributions of distances between subsequences. Then, we define a generative model for melodies given chords and rhythms based on modeling sequences of Narmour featur...

  18. TRACKING CLIMATE MODELS

    Data.gov (United States)

    National Aeronautics and Space Administration — CLAIRE MONTELEONI*, GAVIN SCHMIDT, AND SHAILESH SAROHA* Climate models are complex mathematical models designed by meteorologists, geophysicists, and climate...

  19. Environmental Modeling Center

    Data.gov (United States)

    Federal Laboratory Consortium — The Environmental Modeling Center provides the computational tools to perform geostatistical analysis, to model ground water and atmospheric releases for comparison...

  20. Multilevel modeling using R

    CERN Document Server

    Finch, W Holmes; Kelley, Ken

    2014-01-01

    A powerful tool for analyzing nested designs in a variety of fields, multilevel/hierarchical modeling allows researchers to account for data collected at multiple levels. Multilevel Modeling Using R provides you with a helpful guide to conducting multilevel data modeling using the R software environment.After reviewing standard linear models, the authors present the basics of multilevel models and explain how to fit these models using R. They then show how to employ multilevel modeling with longitudinal data and demonstrate the valuable graphical options in R. The book also describes models fo

  1. Global Business Models

    DEFF Research Database (Denmark)

    Rask, Morten

    insight from the literature about business models, international product policy, international entry modes and globalization into a conceptual model of relevant design elements of global business models, enabling global business model innovation to deal with differences in a downstream perspective...... regarding the customer interface and in an upstream perspective regarding the supply infrastructure. The paper offers a coherent conceptual dynamic meta-model of global business model innovation. Students, scholars and managers within the field of international business can use this conceptualization...... to understand, to study, and to create global business model innovation. Managerial and research implications draw on the developed ideal type of global business model innovation....

  2. Continuous system modeling

    Science.gov (United States)

    Cellier, Francois E.

    1991-01-01

    A comprehensive and systematic introduction is presented for the concepts associated with 'modeling', involving the transition from a physical system down to an abstract description of that system in the form of a set of differential and/or difference equations, and basing its treatment of modeling on the mathematics of dynamical systems. Attention is given to the principles of passive electrical circuit modeling, planar mechanical systems modeling, hierarchical modular modeling of continuous systems, and bond-graph modeling. Also discussed are modeling in equilibrium thermodynamics, population dynamics, and system dynamics, inductive reasoning, artificial neural networks, and automated model synthesis.

  3. Understandings of 'Modelling'

    DEFF Research Database (Denmark)

    Andresen, Mette

    2007-01-01

    This paper meets the common critique of the teaching of non-authentic modelling in school mathematics. In the paper, non-authentic modelling is related to a change of view on the intentions of modelling from knowledge about applications of mathematical models to modelling for concept formation. Non......-authentic modelling is also linked with the potentials of exploration of ready-made models as a forerunner for more authentic modelling processes. The discussion includes analysis of an episode of students? work in the classroom, which serves to illustrate how concept formation may be linked to explorations of a non...

  4. Interfacing materials models with fire field models

    Energy Technology Data Exchange (ETDEWEB)

    Nicolette, V.F.; Tieszen, S.R.; Moya, J.L.

    1995-12-01

    For flame spread over solid materials, there has traditionally been a large technology gap between fundamental combustion research and the somewhat simplistic approaches used for practical, real-world applications. Recent advances in computational hardware and computational fluid dynamics (CFD)-based software have led to the development of fire field models. These models, when used in conjunction with material burning models, have the potential to bridge the gap between research and application by implementing physics-based engineering models in a transient, multi-dimensional tool. This paper discusses the coupling that is necessary between fire field models and burning material models for the simulation of solid material fires. Fire field models are capable of providing detailed information about the local fire environment. This information serves as an input to the solid material combustion submodel, which subsequently calculates the impact of the fire environment on the material. The response of the solid material (in terms of thermal response, decomposition, charring, and off-gassing) is then fed back into the field model as a source of mass, momentum and energy. The critical parameters which must be passed between the field model and the material burning model have been identified. Many computational issues must be addressed when developing such an interface. Some examples include the ability to track multiple fuels and species, local ignition criteria, and the need to use local grid refinement over the burning material of interest.

  5. Combustion modeling in a model combustor

    Institute of Scientific and Technical Information of China (English)

    L.Y.Jiang; I.Campbell; K.Su

    2007-01-01

    The flow-field of a propane-air diffusion flame combustor with interior and exterior conjugate heat transfers was numerically studied.Results obtained from four combustion models,combined with the re-normalization group (RNG) k-ε turbulence model,discrete ordinates radiation model and enhanced wall treatment are presented and discussed.The results are compared with a comprehensive database obtained from a series of experimental measurements.The flow patterns and the recirculation zone length in the combustion chamber are accurately predicted,and the mean axial velocities are in fairly good agreement with the experimental data,particularly at downstream sections for all four combustion models.The mean temperature profiles are captured fairly well by the eddy dissipation (EDS),probability density function (PDF),and laminar flamelet combustion models.However,the EDS-finite-rate combustion model fails to provide an acceptable temperature field.In general,the flamelet model illustrates little superiority over the PDF model,and to some extent the PDF model shows better performance than the EDS model.

  6. Regularized Structural Equation Modeling.

    Science.gov (United States)

    Jacobucci, Ross; Grimm, Kevin J; McArdle, John J

    A new method is proposed that extends the use of regularization in both lasso and ridge regression to structural equation models. The method is termed regularized structural equation modeling (RegSEM). RegSEM penalizes specific parameters in structural equation models, with the goal of creating easier to understand and simpler models. Although regularization has gained wide adoption in regression, very little has transferred to models with latent variables. By adding penalties to specific parameters in a structural equation model, researchers have a high level of flexibility in reducing model complexity, overcoming poor fitting models, and the creation of models that are more likely to generalize to new samples. The proposed method was evaluated through a simulation study, two illustrative examples involving a measurement model, and one empirical example involving the structural part of the model to demonstrate RegSEM's utility.

  7. Wastewater treatment models

    DEFF Research Database (Denmark)

    Gernaey, Krist; Sin, Gürkan

    2011-01-01

    The state-of-the-art level reached in modeling wastewater treatment plants (WWTPs) is reported. For suspended growth systems, WWTP models have evolved from simple description of biological removal of organic carbon and nitrogen in aeration tanks (ASM1 in 1987) to more advanced levels including...... of WWTP modeling by linking the wastewater treatment line with the sludge handling line in one modeling platform. Application of WWTP models is currently rather time consuming and thus expensive due to the high model complexity, and requires a great deal of process knowledge and modeling expertise....... Efficient and good modeling practice therefore requires the use of a proper set of guidelines, thus grounding the modeling studies on a general and systematic framework. Last but not least, general limitations of WWTP models – more specifically activated sludge models – are introduced since these define...

  8. Wastewater Treatment Models

    DEFF Research Database (Denmark)

    Gernaey, Krist; Sin, Gürkan

    2008-01-01

    The state-of-the-art level reached in modeling wastewater treatment plants (WWTPs) is reported. For suspended growth systems, WWTP models have evolved from simple description of biological removal of organic carbon and nitrogen in aeration tanks (ASM1 in 1987) to more advanced levels including...... the practice of WWTP modeling by linking the wastewater treatment line with the sludge handling line in one modeling platform. Application of WWTP models is currently rather time consuming and thus expensive due to the high model complexity, and requires a great deal of process knowledge and modeling expertise....... Efficient and good modeling practice therefore requires the use of a proper set of guidelines, thus grounding the modeling studies on a general and systematic framework. Last but not least, general limitations of WWTP models – more specifically, activated sludge models – are introduced since these define...

  9. ROCK PROPERTIES MODEL ANALYSIS MODEL REPORT

    Energy Technology Data Exchange (ETDEWEB)

    Clinton Lum

    2002-02-04

    The purpose of this Analysis and Model Report (AMR) is to document Rock Properties Model (RPM) 3.1 with regard to input data, model methods, assumptions, uncertainties and limitations of model results, and qualification status of the model. The report also documents the differences between the current and previous versions and validation of the model. The rock properties models are intended principally for use as input to numerical physical-process modeling, such as of ground-water flow and/or radionuclide transport. The constraints, caveats, and limitations associated with this model are discussed in the appropriate text sections that follow. This work was conducted in accordance with the following planning documents: WA-0344, ''3-D Rock Properties Modeling for FY 1998'' (SNL 1997, WA-0358), ''3-D Rock Properties Modeling for FY 1999'' (SNL 1999), and the technical development plan, Rock Properties Model Version 3.1, (CRWMS M&O 1999c). The Interim Change Notice (ICNs), ICN 02 and ICN 03, of this AMR were prepared as part of activities being conducted under the Technical Work Plan, TWP-NBS-GS-000003, ''Technical Work Plan for the Integrated Site Model, Process Model Report, Revision 01'' (CRWMS M&O 2000b). The purpose of ICN 03 is to record changes in data input status due to data qualification and verification activities. These work plans describe the scope, objectives, tasks, methodology, and implementing procedures for model construction. The constraints, caveats, and limitations associated with this model are discussed in the appropriate text sections that follow. The work scope for this activity consists of the following: (1) Conversion of the input data (laboratory measured porosity data, x-ray diffraction mineralogy, petrophysical calculations of bound water, and petrophysical calculations of porosity) for each borehole into stratigraphic coordinates; (2) Re-sampling and merging of data sets; (3

  10. Model Reduction of Nonlinear Fire Dynamics Models

    OpenAIRE

    Lattimer, Alan Martin

    2016-01-01

    Due to the complexity, multi-scale, and multi-physics nature of the mathematical models for fires, current numerical models require too much computational effort to be useful in design and real-time decision making, especially when dealing with fires over large domains. To reduce the computational time while retaining the complexity of the domain and physics, our research has focused on several reduced-order modeling techniques. Our contributions are improving wildland fire reduced-order mod...

  11. Better models are more effectively connected models

    Science.gov (United States)

    Nunes, João Pedro; Bielders, Charles; Darboux, Frederic; Fiener, Peter; Finger, David; Turnbull-Lloyd, Laura; Wainwright, John

    2016-04-01

    The concept of hydrologic and geomorphologic connectivity describes the processes and pathways which link sources (e.g. rainfall, snow and ice melt, springs, eroded areas and barren lands) to accumulation areas (e.g. foot slopes, streams, aquifers, reservoirs), and the spatial variations thereof. There are many examples of hydrological and sediment connectivity on a watershed scale; in consequence, a process-based understanding of connectivity is crucial to help managers understand their systems and adopt adequate measures for flood prevention, pollution mitigation and soil protection, among others. Modelling is often used as a tool to understand and predict fluxes within a catchment by complementing observations with model results. Catchment models should therefore be able to reproduce the linkages, and thus the connectivity of water and sediment fluxes within the systems under simulation. In modelling, a high level of spatial and temporal detail is desirable to ensure taking into account a maximum number of components, which then enables connectivity to emerge from the simulated structures and functions. However, computational constraints and, in many cases, lack of data prevent the representation of all relevant processes and spatial/temporal variability in most models. In most cases, therefore, the level of detail selected for modelling is too coarse to represent the system in a way in which connectivity can emerge; a problem which can be circumvented by representing fine-scale structures and processes within coarser scale models using a variety of approaches. This poster focuses on the results of ongoing discussions on modelling connectivity held during several workshops within COST Action Connecteur. It assesses the current state of the art of incorporating the concept of connectivity in hydrological and sediment models, as well as the attitudes of modellers towards this issue. The discussion will focus on the different approaches through which connectivity

  12. Multiple Model Approaches to Modelling and Control,

    DEFF Research Database (Denmark)

    on the ease with which prior knowledge can be incorporated. It is interesting to note that researchers in Control Theory, Neural Networks,Statistics, Artificial Intelligence and Fuzzy Logic have more or less independently developed very similar modelling methods, calling them Local ModelNetworks, Operating...... of introduction of existing knowledge, as well as the ease of model interpretation. This book attempts to outlinemuch of the common ground between the various approaches, encouraging the transfer of ideas.Recent progress in algorithms and analysis is presented, with constructive algorithms for automated model...

  13. Integrity modelling of tropospheric delay models

    Science.gov (United States)

    Rózsa, Szabolcs; Bastiaan Ober, Pieter; Mile, Máté; Ambrus, Bence; Juni, Ildikó

    2017-04-01

    The effect of the neutral atmosphere on signal propagation is routinely estimated by various tropospheric delay models in satellite navigation. Although numerous studies can be found in the literature investigating the accuracy of these models, for safety-of-life applications it is crucial to study and model the worst case performance of these models using very low recurrence frequencies. The main objective of the INTegrity of TROpospheric models (INTRO) project funded by the ESA PECS programme is to establish a model (or models) of the residual error of existing tropospheric delay models for safety-of-life applications. Such models are required to overbound rare tropospheric delays and should thus include the tails of the error distributions. Their use should lead to safe error bounds on the user position and should allow computation of protection levels for the horizontal and vertical position errors. The current tropospheric model from the RTCA SBAS Minimal Operational Standards has an associated residual error that equals 0.12 meters in the vertical direction. This value is derived by simply extrapolating the observed distribution of the residuals into the tail (where no data is present) and then taking the point where the cumulative distribution has an exceedance level would be 10-7.While the resulting standard deviation is much higher than the estimated standard variance that best fits the data (0.05 meters), it surely is conservative for most applications. In the context of the INTRO project some widely used and newly developed tropospheric delay models (e.g. RTCA MOPS, ESA GALTROPO and GPT2W) were tested using 16 years of daily ERA-INTERIM Reanalysis numerical weather model data and the raytracing technique. The results showed that the performance of some of the widely applied models have a clear seasonal dependency and it is also affected by a geographical position. In order to provide a more realistic, but still conservative estimation of the residual

  14. Numerical Modelling of Streams

    DEFF Research Database (Denmark)

    Vestergaard, Kristian

    In recent years there has been a sharp increase in the use of numerical water quality models. Numeric water quality modeling can be divided into three steps: Hydrodynamic modeling for the determination of stream flow and water levels. Modelling of transport and dispersion of a conservative...

  15. Graphical Models with R

    DEFF Research Database (Denmark)

    Højsgaard, Søren; Edwards, David; Lauritzen, Steffen

    , the book provides examples of how more advanced aspects of graphical modeling can be represented and handled within R. Topics covered in the seven chapters include graphical models for contingency tables, Gaussian and mixed graphical models, Bayesian networks and modeling high dimensional data...

  16. Dynamic Latent Classification Model

    DEFF Research Database (Denmark)

    Zhong, Shengtong; Martínez, Ana M.; Nielsen, Thomas Dyhre

    as possible. Motivated by this problem setting, we propose a generative model for dynamic classification in continuous domains. At each time point the model can be seen as combining a naive Bayes model with a mixture of factor analyzers (FA). The latent variables of the FA are used to capture the dynamics...... in the process as well as modeling dependences between attributes....

  17. HRM: HII Region Models

    Science.gov (United States)

    Wenger, Trey V.; Kepley, Amanda K.; Balser, Dana S.

    2017-07-01

    HII Region Models fits HII region models to observed radio recombination line and radio continuum data. The algorithm includes the calculations of departure coefficients to correct for non-LTE effects. HII Region Models has been used to model star formation in the nucleus of IC 342.

  18. Multilevel IRT Model Assessment

    NARCIS (Netherlands)

    Fox, Jean-Paul; Ark, L. Andries; Croon, Marcel A.

    2005-01-01

    Modelling complex cognitive and psychological outcomes in, for example, educational assessment led to the development of generalized item response theory (IRT) models. A class of models was developed to solve practical and challenging educational problems by generalizing the basic IRT models. An IRT

  19. Models for Dynamic Applications

    DEFF Research Database (Denmark)

    2011-01-01

    be applied to formulate, analyse and solve these dynamic problems and how in the case of the fuel cell problem the model consists of coupledmeso and micro scale models. It is shown how data flows are handled between the models and how the solution is obtained within the modelling environment....

  20. Multivariate GARCH models

    DEFF Research Database (Denmark)

    Silvennoinen, Annastiina; Teräsvirta, Timo

    This article contains a review of multivariate GARCH models. Most common GARCH models are presented and their properties considered. This also includes nonparametric and semiparametric models. Existing specification and misspecification tests are discussed. Finally, there is an empirical example...... in which several multivariate GARCH models are fitted to the same data set and the results compared....

  1. The Model Confidence Set

    DEFF Research Database (Denmark)

    Hansen, Peter Reinhard; Lunde, Asger; Nason, James M.

    The paper introduces the model confidence set (MCS) and applies it to the selection of models. A MCS is a set of models that is constructed such that it will contain the best model with a given level of confidence. The MCS is in this sense analogous to a confidence interval for a parameter. The M...

  2. Modelling Railway Interlocking Systems

    DEFF Research Database (Denmark)

    Lindegaard, Morten Peter; Viuf, P.; Haxthausen, Anne Elisabeth

    2000-01-01

    In this report we present a model of interlocking systems, and describe how the model may be validated by simulation. Station topologies are modelled by graphs in which the nodes denote track segments, and the edges denote connectivity for train traÆc. Points and signals are modelled by annotatio...

  3. AIDS Epidemiological models

    Science.gov (United States)

    Rahmani, Fouad Lazhar

    2010-11-01

    The aim of this paper is to present mathematical modelling of the spread of infection in the context of the transmission of the human immunodeficiency virus (HIV) and the acquired immune deficiency syndrome (AIDS). These models are based in part on the models suggested in the field of th AIDS mathematical modelling as reported by ISHAM [6].

  4. Multivariate GARCH models

    DEFF Research Database (Denmark)

    Silvennoinen, Annastiina; Teräsvirta, Timo

    This article contains a review of multivariate GARCH models. Most common GARCH models are presented and their properties considered. This also includes nonparametric and semiparametric models. Existing specification and misspecification tests are discussed. Finally, there is an empirical example...... in which several multivariate GARCH models are fitted to the same data set and the results compared....

  5. Multilevel IRT Model Assessment

    NARCIS (Netherlands)

    Fox, Gerardus J.A.; Ark, L. Andries; Croon, Marcel A.

    2005-01-01

    Modelling complex cognitive and psychological outcomes in, for example, educational assessment led to the development of generalized item response theory (IRT) models. A class of models was developed to solve practical and challenging educational problems by generalizing the basic IRT models. An IRT

  6. Biomass Scenario Model

    Energy Technology Data Exchange (ETDEWEB)

    2015-09-01

    The Biomass Scenario Model (BSM) is a unique, carefully validated, state-of-the-art dynamic model of the domestic biofuels supply chain which explicitly focuses on policy issues, their feasibility, and potential side effects. It integrates resource availability, physical/technological/economic constraints, behavior, and policy. The model uses a system dynamics simulation (not optimization) to model dynamic interactions across the supply chain.

  7. Lumped-parameter models

    Energy Technology Data Exchange (ETDEWEB)

    Ibsen, Lars Bo; Liingaard, M.

    2006-12-15

    A lumped-parameter model represents the frequency dependent soil-structure interaction of a massless foundation placed on or embedded into an unbounded soil domain. In this technical report the steps of establishing a lumped-parameter model are presented. Following sections are included in this report: Static and dynamic formulation, Simple lumped-parameter models and Advanced lumped-parameter models. (au)

  8. Plant development models

    NARCIS (Netherlands)

    Chuine, I.; Garcia de Cortazar-Atauri, I.; Kramer, K.; Hänninen, H.

    2013-01-01

    In this chapter we provide a brief overview of plant phenology modeling, focusing on mechanistic phenological models. After a brief history of plant phenology modeling, we present the different models which have been described in the literature so far and highlight the main differences between them,

  9. Generic Market Models

    NARCIS (Netherlands)

    R. Pietersz (Raoul); M. van Regenmortel

    2005-01-01

    textabstractCurrently, there are two market models for valuation and risk management of interest rate derivatives, the LIBOR and swap market models. In this paper, we introduce arbitrage-free constant maturity swap (CMS) market models and generic market models featuring forward rates that span perio

  10. A Model for Conversation

    DEFF Research Database (Denmark)

    Ayres, Phil

    2012-01-01

    This essay discusses models. It examines what models are, the roles models perform and suggests various intentions that underlie their construction and use. It discusses how models act as a conversational partner, and how they support various forms of conversation within the conversational activity...... of design. Three distinctions are drawn through which to develop this discussion of models in an architectural context. An examination of these distinctions serves to nuance particular characteristics and roles of models, the modelling activity itself and those engaged in it....

  11. Talk about toy models

    Science.gov (United States)

    Luczak, Joshua

    2017-02-01

    Scientific models are frequently discussed in philosophy of science. A great deal of the discussion is centred on approximation, idealisation, and on how these models achieve their representational function. Despite the importance, distinct nature, and high presence of toy models, they have received little attention from philosophers. This paper hopes to remedy this situation. It aims to elevate the status of toy models: by distinguishing them from approximations and idealisations, by highlighting and elaborating on several ways the Kac ring, a simple statistical mechanical model, is used as a toy model, and by explaining why toy models can be used to successfully carry out important work without performing a representational function.

  12. Latent classification models

    DEFF Research Database (Denmark)

    Langseth, Helge; Nielsen, Thomas Dyhre

    2005-01-01

    One of the simplest, and yet most consistently well-performing setof classifiers is the \\NB models. These models rely on twoassumptions: $(i)$ All the attributes used to describe an instanceare conditionally independent given the class of that instance,and $(ii)$ all attributes follow a specific...... parametric family ofdistributions.  In this paper we propose a new set of models forclassification in continuous domains, termed latent classificationmodels. The latent classification model can roughly be seen ascombining the \\NB model with a mixture of factor analyzers,thereby relaxing the assumptions...... classification model, and wedemonstrate empirically that the accuracy of the proposed model issignificantly higher than the accuracy of other probabilisticclassifiers....

  13. Wastewater treatment models

    DEFF Research Database (Denmark)

    Gernaey, Krist; Sin, Gürkan

    2011-01-01

    The state-of-the-art level reached in modeling wastewater treatment plants (WWTPs) is reported. For suspended growth systems, WWTP models have evolved from simple description of biological removal of organic carbon and nitrogen in aeration tanks (ASM1 in 1987) to more advanced levels including...... of WWTP modeling by linking the wastewater treatment line with the sludge handling line in one modeling platform. Application of WWTP models is currently rather time consuming and thus expensive due to the high model complexity, and requires a great deal of process knowledge and modeling expertise...

  14. Wastewater Treatment Models

    DEFF Research Database (Denmark)

    Gernaey, Krist; Sin, Gürkan

    2008-01-01

    The state-of-the-art level reached in modeling wastewater treatment plants (WWTPs) is reported. For suspended growth systems, WWTP models have evolved from simple description of biological removal of organic carbon and nitrogen in aeration tanks (ASM1 in 1987) to more advanced levels including...... the practice of WWTP modeling by linking the wastewater treatment line with the sludge handling line in one modeling platform. Application of WWTP models is currently rather time consuming and thus expensive due to the high model complexity, and requires a great deal of process knowledge and modeling expertise...

  15. The Hospitable Meal Model

    DEFF Research Database (Denmark)

    Justesen, Lise; Overgaard, Svend Skafte

    2017-01-01

    This article presents an analytical model that aims to conceptualize how meal experiences are framed when taking into account a dynamic understanding of hospitality: the meal model is named The Hospitable Meal Model. The idea behind The Hospitable Meal Model is to present a conceptual model...... that can serve as a frame for developing hospitable meal competencies among professionals working within the area of institutional foodservices as well as a conceptual model for analysing meal experiences. The Hospitable Meal Model transcends and transforms existing meal models by presenting a more open......-ended approach towards meal experiences. The underlying purpose of The Hospitable Meal Model is to provide the basis for creating value for the individuals involved in institutional meal services. The Hospitable Meal Model was developed on the basis of an empirical study on hospital meal experiences explored...

  16. Protein Models Comparator

    CERN Document Server

    Widera, Paweł

    2011-01-01

    The process of comparison of computer generated protein structural models is an important element of protein structure prediction. It has many uses including model quality evaluation, selection of the final models from a large set of candidates or optimisation of parameters of energy functions used in template free modelling and refinement. Although many protein comparison methods are available online on numerous web servers, their ability to handle a large scale model comparison is often very limited. Most of the servers offer only a single pairwise structural comparison, and they usually do not provide a model-specific comparison with a fixed alignment between the models. To bridge the gap between the protein and model structure comparison we have developed the Protein Models Comparator (pm-cmp). To be able to deliver the scalability on demand and handle large comparison experiments the pm-cmp was implemented "in the cloud". Protein Models Comparator is a scalable web application for a fast distributed comp...

  17. Nonuniform Markov models

    CERN Document Server

    Ristad, E S; Ristad, Eric Sven; Thomas, Robert G.

    1996-01-01

    A statistical language model assigns probability to strings of arbitrary length. Unfortunately, it is not possible to gather reliable statistics on strings of arbitrary length from a finite corpus. Therefore, a statistical language model must decide that each symbol in a string depends on at most a small, finite number of other symbols in the string. In this report we propose a new way to model conditional independence in Markov models. The central feature of our nonuniform Markov model is that it makes predictions of varying lengths using contexts of varying lengths. Experiments on the Wall Street Journal reveal that the nonuniform model performs slightly better than the classic interpolated Markov model. This result is somewhat remarkable because both models contain identical numbers of parameters whose values are estimated in a similar manner. The only difference between the two models is how they combine the statistics of longer and shorter strings. Keywords: nonuniform Markov model, interpolated Markov m...

  18. Lumped Thermal Household Model

    DEFF Research Database (Denmark)

    Biegel, Benjamin; Andersen, Palle; Stoustrup, Jakob

    2013-01-01

    a lumped model approach as an alternative to the individual models. In the lumped model, the portfolio is seen as baseline consumption superimposed with an ideal storage of limited power and energy capacity. The benefit of such a lumped model is that the computational effort of flexibility optimization......In this paper we discuss two different approaches to model the flexible power consumption of heat pump heated households: individual household modeling and lumped modeling. We illustrate that a benefit of individual modeling is that we can overview and optimize the complete flexibility of a heat...... pump portfolio. Following, we illustrate two disadvantages of individual models, namely that it requires much computational effort to optimize over a large portfolio, and second that it is difficult to accurately model the houses in certain time periods due to local disturbances. Finally, we propose...

  19. Calibrated Properties Model

    Energy Technology Data Exchange (ETDEWEB)

    C. Ahlers; H. Liu

    2000-03-12

    The purpose of this Analysis/Model Report (AMR) is to document the Calibrated Properties Model that provides calibrated parameter sets for unsaturated zone (UZ) flow and transport process models for the Yucca Mountain Site Characterization Project (YMP). This work was performed in accordance with the ''AMR Development Plan for U0035 Calibrated Properties Model REV00. These calibrated property sets include matrix and fracture parameters for the UZ Flow and Transport Model (UZ Model), drift seepage models, drift-scale and mountain-scale coupled-processes models, and Total System Performance Assessment (TSPA) models as well as Performance Assessment (PA) and other participating national laboratories and government agencies. These process models provide the necessary framework to test conceptual hypotheses of flow and transport at different scales and predict flow and transport behavior under a variety of climatic and thermal-loading conditions.

  20. Introduction to Adjoint Models

    Science.gov (United States)

    Errico, Ronald M.

    2015-01-01

    In this lecture, some fundamentals of adjoint models will be described. This includes a basic derivation of tangent linear and corresponding adjoint models from a parent nonlinear model, the interpretation of adjoint-derived sensitivity fields, a description of methods of automatic differentiation, and the use of adjoint models to solve various optimization problems, including singular vectors. Concluding remarks will attempt to correct common misconceptions about adjoint models and their utilization.

  1. Modeling cholera outbreaks

    OpenAIRE

    Chao, Dennis L.; Ira M Longini; Morris, J. Glenn

    2014-01-01

    Mathematical modeling can be a valuable tool for studying infectious disease outbreak dynamics and simulating the effects of possible interventions. Here, we describe approaches to modeling cholera outbreaks and how models have been applied to explore intervention strategies, particularly in Haiti. Mathematical models can play an important role in formulating and evaluating complex cholera outbreak response options. Major challenges to cholera modeling are insufficient data for calibrating mo...

  2. Business Model Visualization

    OpenAIRE

    Zagorsek, Branislav

    2013-01-01

    Business model describes the company’s most important activities, proposed value, and the compensation for the value. Business model visualization enables to simply and systematically capture and describe the most important components of the business model while the standardization of the concept allows the comparison between companies. There are several possibilities how to visualize the model. The aim of this paper is to describe the options for business model visualization and business mod...

  3. Diffeomorphic Statistical Deformation Models

    DEFF Research Database (Denmark)

    Hansen, Michael Sass; Hansen, Mads/Fogtman; Larsen, Rasmus

    2007-01-01

    In this paper we present a new method for constructing diffeomorphic statistical deformation models in arbitrary dimensional images with a nonlinear generative model and a linear parameter space. Our deformation model is a modified version of the diffeomorphic model introduced by Cootes et al. Th...... with ground truth in form of manual expert annotations, and compared to Cootes's model. We anticipate applications in unconstrained diffeomorphic synthesis of images, e.g. for tracking, segmentation, registration or classification purposes....

  4. Dimension of linear models

    DEFF Research Database (Denmark)

    Høskuldsson, Agnar

    1996-01-01

    Determination of the proper dimension of a given linear model is one of the most important tasks in the applied modeling work. We consider here eight criteria that can be used to determine the dimension of the model, or equivalently, the number of components to use in the model. Four...... the basic problems in determining the dimension of linear models. Then each of the eight measures are treated. The results are illustrated by examples....

  5. Modeling cholera outbreaks

    OpenAIRE

    Dennis L Chao; Longini, Ira M.; Morris, J. Glenn

    2014-01-01

    Mathematical modeling can be a valuable tool for studying infectious disease outbreak dynamics and simulating the effects of possible interventions. Here, we describe approaches to modeling cholera outbreaks and how models have been applied to explore intervention strategies, particularly in Haiti. Mathematical models can play an important role in formulating and evaluating complex cholera outbreak response options. Major challenges to cholera modeling are insufficient data for calibrating mo...

  6. Multiple Model Approaches to Modelling and Control,

    DEFF Research Database (Denmark)

    Why Multiple Models?This book presents a variety of approaches which produce complex models or controllers by piecing together a number of simpler subsystems. Thisdivide-and-conquer strategy is a long-standing and general way of copingwith complexity in engineering systems, nature and human probl...

  7. Model Checking of Boolean Process Models

    CERN Document Server

    Schneider, Christoph

    2011-01-01

    In the field of Business Process Management formal models for the control flow of business processes have been designed since more than 15 years. Which methods are best suited to verify the bulk of these models? The first step is to select a formal language which fixes the semantics of the models. We adopt the language of Boolean systems as reference language for Boolean process models. Boolean systems form a simple subclass of coloured Petri nets. Their characteristics are low tokens to model explicitly states with a subsequent skipping of activations and arbitrary logical rules of type AND, XOR, OR etc. to model the split and join of the control flow. We apply model checking as a verification method for the safeness and liveness of Boolean systems. Model checking of Boolean systems uses the elementary theory of propositional logic, no modal operators are needed. Our verification builds on a finite complete prefix of a certain T-system attached to the Boolean system. It splits the processes of the Boolean sy...

  8. Pavement Aging Model by Response Surface Modeling

    Directory of Open Access Journals (Sweden)

    Manzano-Ramírez A.

    2011-10-01

    Full Text Available In this work, surface course aging was modeled by Response Surface Methodology (RSM. The Marshall specimens were placed in a conventional oven for time and temperature conditions established on the basis of the environment factors of the region where the surface course is constructed by AC-20 from the Ing. Antonio M. Amor refinery. Volatilized material (VM, load resistance increment (ΔL and flow resistance increment (ΔF models were developed by the RSM. Cylindrical specimens with real aging were extracted from the surface course pilot to evaluate the error of the models. The VM model was adequate, in contrast (ΔL and (ΔF models were almost adequate with an error of 20 %, that was associated with the other environmental factors, which were not considered at the beginning of the research.

  9. Paeonol attenuates inflammation-mediated neurotoxicity and microglial activation

    Institute of Scientific and Technical Information of China (English)

    Kyong Nyon Nam; Byung-Cheol Woo; Sang-Kwan Moon; Seong-Uk Park; Joo-young Park; Jae-Woong Hwang; Hyung-Sup Bae; Chang-Nam Ko; Eunjoo Hwang Lee

    2013-01-01

    Chronic activation of microglial cells endangers neuronal survival through the release of various proinflammatory and neurotoxic factors. The root of Paeonia lactiflora Pall has been considered useful for the treatment of various disorders in traditional oriental medicine. Paeonol, found in the root of Paeonia lactiflora Pall, has a wide range of pharmacological functions, including anti-oxidative, anti-inflammatory and neuroprotective activities. The objective of this study was to examine the efficacy of paeonol in the repression of inflammation-induced neurotoxicity and microglial cell activation. Organotypic hippocampal slice cultures and primary microglial cells from rat brain were stimulated with bacterial lipopolysaccharide. Paeonol pretreatment was performed for 30 minutes prior to lipopolysaccharide addition. Cell viability and nitrite (the production of nitric oxide), tumor necrosis factor-alpha and interleukin-1beta products were measured after lipopolysaccharide treatment. In organotypic hippocampal slice cultures, paeonol blocked lipopolysaccharide-related hippocampal cell death and inhibited the release of nitrite and interleukin-1beta. Paeonol was effective in inhibiting nitric oxide release from primary microglial cells. It also reduced the lipopolysaccharide-stimulated release of tumor necrosis factor-alpha and interleukin-1β from microglial cells. Paeonol possesses neuroprotective activity in a model of inflammation-induced neurotoxicity and reduces the release of neurotoxic and proinflammatory factors in activated microglial cells.

  10. Model Validation Status Review

    Energy Technology Data Exchange (ETDEWEB)

    E.L. Hardin

    2001-11-28

    The primary objective for the Model Validation Status Review was to perform a one-time evaluation of model validation associated with the analysis/model reports (AMRs) containing model input to total-system performance assessment (TSPA) for the Yucca Mountain site recommendation (SR). This review was performed in response to Corrective Action Request BSC-01-C-01 (Clark 2001, Krisha 2001) pursuant to Quality Assurance review findings of an adverse trend in model validation deficiency. The review findings in this report provide the following information which defines the extent of model validation deficiency and the corrective action needed: (1) AMRs that contain or support models are identified, and conversely, for each model the supporting documentation is identified. (2) The use for each model is determined based on whether the output is used directly for TSPA-SR, or for screening (exclusion) of features, events, and processes (FEPs), and the nature of the model output. (3) Two approaches are used to evaluate the extent to which the validation for each model is compliant with AP-3.10Q (Analyses and Models). The approaches differ in regard to whether model validation is achieved within individual AMRs as originally intended, or whether model validation could be readily achieved by incorporating information from other sources. (4) Recommendations are presented for changes to the AMRs, and additional model development activities or data collection, that will remedy model validation review findings, in support of licensing activities. The Model Validation Status Review emphasized those AMRs that support TSPA-SR (CRWMS M&O 2000bl and 2000bm). A series of workshops and teleconferences was held to discuss and integrate the review findings. The review encompassed 125 AMRs (Table 1) plus certain other supporting documents and data needed to assess model validity. The AMRs were grouped in 21 model areas representing the modeling of processes affecting the natural and

  11. Product and Process Modelling

    DEFF Research Database (Denmark)

    Cameron, Ian T.; Gani, Rafiqul

    This book covers the area of product and process modelling via a case study approach. It addresses a wide range of modelling applications with emphasis on modelling methodology and the subsequent in-depth analysis of mathematical models to gain insight via structural aspects of the models....... These approaches are put into the context of life cycle modelling, where multiscale and multiform modelling is increasingly prevalent in the 21st century. The book commences with a discussion of modern product and process modelling theory and practice followed by a series of case studies drawn from a variety...... to biotechnology applications, food, polymer and human health application areas. The book highlights to important nature of modern product and process modelling in the decision making processes across the life cycle. As such it provides an important resource for students, researchers and industrial practitioners....

  12. Practical Marginalized Multilevel Models.

    Science.gov (United States)

    Griswold, Michael E; Swihart, Bruce J; Caffo, Brian S; Zeger, Scott L

    2013-01-01

    Clustered data analysis is characterized by the need to describe both systematic variation in a mean model and cluster-dependent random variation in an association model. Marginalized multilevel models embrace the robustness and interpretations of a marginal mean model, while retaining the likelihood inference capabilities and flexible dependence structures of a conditional association model. Although there has been increasing recognition of the attractiveness of marginalized multilevel models, there has been a gap in their practical application arising from a lack of readily available estimation procedures. We extend the marginalized multilevel model to allow for nonlinear functions in both the mean and association aspects. We then formulate marginal models through conditional specifications to facilitate estimation with mixed model computational solutions already in place. We illustrate the MMM and approximate MMM approaches on a cerebrovascular deficiency crossover trial using SAS and an epidemiological study on race and visual impairment using R. Datasets, SAS and R code are included as supplemental materials.

  13. Modelling Foundations and Applications

    DEFF Research Database (Denmark)

    This book constitutes the refereed proceedings of the 8th European Conference on Modelling Foundations and Applications, held in Kgs. Lyngby, Denmark, in July 2012. The 20 revised full foundations track papers and 10 revised full applications track papers presented were carefully reviewed...... and selected from 81 submissions. Papers on all aspects of MDE were received, including topics such as architectural modelling and product lines, code generation, domain-specic modeling, metamodeling, model analysis and verication, model management, model transformation and simulation. The breadth of topics...

  14. On Communication Models

    Institute of Scientific and Technical Information of China (English)

    蒋娜; 谢有琪

    2012-01-01

    With the development of human society, the social hub enlarges beyond one community to the extent that the world is deemed as a community as a whole. Communication, therefore, plays an increasingly important role in our daily life. As a consequence, communication model or the definition of which is not so much a definition as a guide in communication. However, some existed communication models are not as practical as it was. This paper tries to make an overall contrast among three communication models Coded Model, Gable Communication Model and Ostensive Inferential Model, to see how they assist people to comprehend verbal and non -verbal communication.

  15. Modeling worldwide highway networks

    Science.gov (United States)

    Villas Boas, Paulino R.; Rodrigues, Francisco A.; da F. Costa, Luciano

    2009-12-01

    This Letter addresses the problem of modeling the highway systems of different countries by using complex networks formalism. More specifically, we compare two traditional geographical models with a modified geometrical network model where paths, rather than edges, are incorporated at each step between the origin and the destination vertices. Optimal configurations of parameters are obtained for each model and used for the comparison. The highway networks of Australia, Brazil, India, and Romania are considered and shown to be properly modeled by the modified geographical model.

  16. THE IMPROVED XINANJIANG MODEL

    Institute of Scientific and Technical Information of China (English)

    LI Zhi-jia; YAO Cheng; KONG Xiang-guang

    2005-01-01

    To improve the Xinanjiang model, the runoff generating from infiltration-excess is added to the model.The another 6 parameters are added to Xinanjiang model.In principle, the improved Xinanjiang model can be used to simulate runoff in the humid, semi-humid and also semi-arid regions.The application in Yi River shows the improved Xinanjiang model could forecast discharge with higher accuracy and can satisfy the practical requirements.It also shows that the improved model is reasonable.

  17. Microsoft tabular modeling cookbook

    CERN Document Server

    Braak, Paul te

    2013-01-01

    This book follows a cookbook style with recipes explaining the steps for developing analytic data using Business Intelligence Semantic Models.This book is designed for developers who wish to develop powerful and dynamic models for users as well as those who are responsible for the administration of models in corporate environments. It is also targeted at analysts and users of Excel who wish to advance their knowledge of Excel through the development of tabular models or who wish to analyze data through tabular modeling techniques. We assume no prior knowledge of tabular modeling

  18. Five models of capitalism

    Directory of Open Access Journals (Sweden)

    Luiz Carlos Bresser-Pereira

    2012-03-01

    Full Text Available Besides analyzing capitalist societies historically and thinking of them in terms of phases or stages, we may compare different models or varieties of capitalism. In this paper I survey the literature on this subject, and distinguish the classification that has a production or business approach from those that use a mainly political criterion. I identify five forms of capitalism: among the rich countries, the liberal democratic or Anglo-Saxon model, the social or European model, and the endogenous social integration or Japanese model; among developing countries, I distinguish the Asian developmental model from the liberal-dependent model that characterizes most other developing countries, including Brazil.

  19. Holographic twin Higgs model.

    Science.gov (United States)

    Geller, Michael; Telem, Ofri

    2015-05-15

    We present the first realization of a "twin Higgs" model as a holographic composite Higgs model. Uniquely among composite Higgs models, the Higgs potential is protected by a new standard model (SM) singlet elementary "mirror" sector at the sigma model scale f and not by the composite states at m_{KK}, naturally allowing for m_{KK} beyond the LHC reach. As a result, naturalness in our model cannot be constrained by the LHC, but may be probed by precision Higgs measurements at future lepton colliders, and by direct searches for Kaluza-Klein excitations at a 100 TeV collider.

  20. Energy-consumption modelling

    Energy Technology Data Exchange (ETDEWEB)

    Reiter, E.R.

    1980-01-01

    A highly sophisticated and accurate approach is described to compute on an hourly or daily basis the energy consumption for space heating by individual buildings, urban sectors, and whole cities. The need for models and specifically weather-sensitive models, composite models, and space-heating models are discussed. Development of the Colorado State University Model, based on heat-transfer equations and on a heuristic, adaptive, self-organizing computation learning approach, is described. Results of modeling energy consumption by the city of Minneapolis and Cheyenne are given. Some data on energy consumption in individual buildings are included.

  1. Empirical Model Building Data, Models, and Reality

    CERN Document Server

    Thompson, James R

    2011-01-01

    Praise for the First Edition "This...novel and highly stimulating book, which emphasizes solving real problems...should be widely read. It will have a positive and lasting effect on the teaching of modeling and statistics in general." - Short Book Reviews This new edition features developments and real-world examples that showcase essential empirical modeling techniques Successful empirical model building is founded on the relationship between data and approximate representations of the real systems that generated that data. As a result, it is essential for researchers who construct these m

  2. Empowerment for Continuous Agent-Environment Systems

    Science.gov (United States)

    2010-09-30

    of data points. For brevity we will only sketch our particular implementation, see (Quiñonero- Candela , Rasmussen, & Williams, 2007) for more...approximation, as was proposed in (Girard, Rasmussen, Quiñonero- Candela , & Murray-Smith, 2003). Since, in our experiments, we will only consider...Rasmussen, C. E., Quiñonero- Candela , J., & Murray-Smith, R. (2003). Gaussian process priors with uncertain inputs: Application to multiple-step ahead time

  3. Develop a Model Component

    Science.gov (United States)

    Ensey, Tyler S.

    2013-01-01

    During my internship at NASA, I was a model developer for Ground Support Equipment (GSE). The purpose of a model developer is to develop and unit test model component libraries (fluid, electrical, gas, etc.). The models are designed to simulate software for GSE (Ground Special Power, Crew Access Arm, Cryo, Fire and Leak Detection System, Environmental Control System (ECS), etc. .) before they are implemented into hardware. These models support verifying local control and remote software for End-Item Software Under Test (SUT). The model simulates the physical behavior (function, state, limits and 110) of each end-item and it's dependencies as defined in the Subsystem Interface Table, Software Requirements & Design Specification (SRDS), Ground Integrated Schematic (GIS), and System Mechanical Schematic.(SMS). The software of each specific model component is simulated through MATLAB's Simulink program. The intensiv model development life cycle is a.s follows: Identify source documents; identify model scope; update schedule; preliminary design review; develop model requirements; update model.. scope; update schedule; detailed design review; create/modify library component; implement library components reference; implement subsystem components; develop a test script; run the test script; develop users guide; send model out for peer review; the model is sent out for verifictionlvalidation; if there is empirical data, a validation data package is generated; if there is not empirical data, a verification package is generated; the test results are then reviewed; and finally, the user. requests accreditation, and a statement of accreditation is prepared. Once each component model is reviewed and approved, they are intertwined together into one integrated model. This integrated model is then tested itself, through a test script and autotest, so that it can be concluded that all models work conjointly, for a single purpose. The component I was assigned, specifically, was a

  4. Biosphere Model Report

    Energy Technology Data Exchange (ETDEWEB)

    D.W. Wu; A.J. Smith

    2004-11-08

    The purpose of this report is to document the biosphere model, the Environmental Radiation Model for Yucca Mountain, Nevada (ERMYN), which describes radionuclide transport processes in the biosphere and associated human exposure that may arise as the result of radionuclide release from the geologic repository at Yucca Mountain. The biosphere model is one of the process models that support the Yucca Mountain Project (YMP) Total System Performance Assessment (TSPA) for the license application (LA), TSPA-LA. The ERMYN provides the capability of performing human radiation dose assessments. This report documents the biosphere model, which includes: (1) Describing the reference biosphere, human receptor, exposure scenarios, and primary radionuclides for each exposure scenario (Section 6.1); (2) Developing a biosphere conceptual model using site-specific features, events, and processes (FEPs) (Section 6.2), the reference biosphere (Section 6.1.1), the human receptor (Section 6.1.2), and approximations (Sections 6.3.1.4 and 6.3.2.4); (3) Building a mathematical model using the biosphere conceptual model (Section 6.3) and published biosphere models (Sections 6.4 and 6.5); (4) Summarizing input parameters for the mathematical model, including the uncertainty associated with input values (Section 6.6); (5) Identifying improvements in the ERMYN compared with the model used in previous biosphere modeling (Section 6.7); (6) Constructing an ERMYN implementation tool (model) based on the biosphere mathematical model using GoldSim stochastic simulation software (Sections 6.8 and 6.9); (7) Verifying the ERMYN by comparing output from the software with hand calculations to ensure that the GoldSim implementation is correct (Section 6.10); (8) Validating the ERMYN by corroborating it with published biosphere models; comparing conceptual models, mathematical models, and numerical results (Section 7).

  5. Major Differences between the Jerome Model and the Horace Model

    Institute of Scientific and Technical Information of China (English)

    朱艳

    2014-01-01

    There are three famous translation models in the field of translation: the Jerome model, the Horace model and the Schleiermacher model. The production and development of the three models have significant influence on the translation. To find the major differences between the two western classical translation theoretical models, we discuss the Jerome model and the Hor-ace model deeply in this paper.

  6. Modelling cointegration in the vector autoregressive model

    DEFF Research Database (Denmark)

    Johansen, Søren

    2000-01-01

    A survey is given of some results obtained for the cointegrated VAR. The Granger representation theorem is discussed and the notions of cointegration and common trends are defined. The statistical model for cointegrated I(1) variables is defined, and it is shown how hypotheses on the cointegrating...... relations can be estimated under suitable identification conditions. The asymptotic theory is briefly mentioned and a few economic applications of the cointegration model are indicated....

  7. Emissions Modeling Clearinghouse

    Data.gov (United States)

    U.S. Environmental Protection Agency — The Emissions Modeling Clearinghouse (EMCH) supports and promotes emissions modeling activities both internal and external to the EPA. Through this site, the EPA...

  8. ASC Champ Orbit Model

    DEFF Research Database (Denmark)

    Riis, Troels; Jørgensen, John Leif

    1999-01-01

    This documents describes a test of the implementation of the ASC orbit model for the Champ satellite.......This documents describes a test of the implementation of the ASC orbit model for the Champ satellite....

  9. World Magnetic Model 2015

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The World Magnetic Model is the standard model used by the U.S. Department of Defense, the U.K. Ministry of Defence, the North Atlantic Treaty Organization (NATO)...

  10. Laboratory of Biological Modeling

    Data.gov (United States)

    Federal Laboratory Consortium — The Laboratory of Biological Modeling is defined by both its methodologies and its areas of application. We use mathematical modeling in many forms and apply it to...

  11. Model comparison in ANOVA.

    Science.gov (United States)

    Rouder, Jeffrey N; Engelhardt, Christopher R; McCabe, Simon; Morey, Richard D

    2016-12-01

    Analysis of variance (ANOVA), the workhorse analysis of experimental designs, consists of F-tests of main effects and interactions. Yet, testing, including traditional ANOVA, has been recently critiqued on a number of theoretical and practical grounds. In light of these critiques, model comparison and model selection serve as an attractive alternative. Model comparison differs from testing in that one can support a null or nested model vis-a-vis a more general alternative by penalizing more flexible models. We argue this ability to support more simple models allows for more nuanced theoretical conclusions than provided by traditional ANOVA F-tests. We provide a model comparison strategy and show how ANOVA models may be reparameterized to better address substantive questions in data analysis.

  12. Graphical Models with R

    DEFF Research Database (Denmark)

    Højsgaard, Søren; Edwards, David; Lauritzen, Steffen

    Graphical models in their modern form have been around since the late 1970s and appear today in many areas of the sciences. Along with the ongoing developments of graphical models, a number of different graphical modeling software programs have been written over the years. In recent years many...... of these software developments have taken place within the R community, either in the form of new packages or by providing an R ingerface to existing software. This book attempts to give the reader a gentle introduction to graphical modeling using R and the main features of some of these packages. In addition......, the book provides examples of how more advanced aspects of graphical modeling can be represented and handled within R. Topics covered in the seven chapters include graphical models for contingency tables, Gaussian and mixed graphical models, Bayesian networks and modeling high dimensional data...

  13. Controlling Modelling Artifacts

    DEFF Research Database (Denmark)

    Smith, Michael James Andrew; Nielson, Flemming; Nielson, Hanne Riis

    2011-01-01

    the possible configurations of the system (for example, by counting the number of components in a certain state). We motivate our methodology with a case study of the LMAC protocol for wireless sensor networks. In particular, we investigate the accuracy of a recently proposed high-level model of LMAC......When analysing the performance of a complex system, we typically build abstract models that are small enough to analyse, but still capture the relevant details of the system. But it is difficult to know whether the model accurately describes the real system, or if its behaviour is due to modelling...... artifacts that were inadvertently introduced. In this paper, we propose a novel methodology to reason about modelling artifacts, given a detailed model and a highlevel (more abstract) model of the same system. By a series of automated abstraction steps, we lift the detailed model to the same state space...

  14. Laboratory of Biological Modeling

    Data.gov (United States)

    Federal Laboratory Consortium — The Laboratory of Biological Modeling is defined by both its methodologies and its areas of application. We use mathematical modeling in many forms and apply it to a...

  15. Modeling EERE deployment programs

    Energy Technology Data Exchange (ETDEWEB)

    Cort, K. A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Hostick, D. J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Belzer, D. B. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Livingston, O. V. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2007-11-01

    The purpose of the project was to identify and characterize the modeling of deployment programs within the EERE Technology Development (TD) programs, address possible improvements to the modeling process, and note gaps in knowledge for future research.

  16. Consistent model driven architecture

    Science.gov (United States)

    Niepostyn, Stanisław J.

    2015-09-01

    The goal of the MDA is to produce software systems from abstract models in a way where human interaction is restricted to a minimum. These abstract models are based on the UML language. However, the semantics of UML models is defined in a natural language. Subsequently the verification of consistency of these diagrams is needed in order to identify errors in requirements at the early stage of the development process. The verification of consistency is difficult due to a semi-formal nature of UML diagrams. We propose automatic verification of consistency of the series of UML diagrams originating from abstract models implemented with our consistency rules. This Consistent Model Driven Architecture approach enables us to generate automatically complete workflow applications from consistent and complete models developed from abstract models (e.g. Business Context Diagram). Therefore, our method can be used to check practicability (feasibility) of software architecture models.

  17. Bounding species distribution models

    Directory of Open Access Journals (Sweden)

    Thomas J. STOHLGREN, Catherine S. JARNEVICH, Wayne E. ESAIAS,Jeffrey T. MORISETTE

    2011-10-01

    Full Text Available Species distribution models are increasing in popularity for mapping suitable habitat for species of management concern. Many investigators now recognize that extrapolations of these models with geographic information systems (GIS might be sensitive to the environmental bounds of the data used in their development, yet there is no recommended best practice for “clamping” model extrapolations. We relied on two commonly used modeling approaches: classification and regression tree (CART and maximum entropy (Maxent models, and we tested a simple alteration of the model extrapolations, bounding extrapolations to the maximum and minimum values of primary environmental predictors, to provide a more realistic map of suitable habitat of hybridized Africanized honey bees in the southwestern United States. Findings suggest that multiple models of bounding, and the most conservative bounding of species distribution models, like those presented here, should probably replace the unbounded or loosely bounded techniques currently used [Current Zoology 57 (5: 642–647, 2011].

  18. CCF model comparison

    Energy Technology Data Exchange (ETDEWEB)

    Pulkkinen, U. [VTT Industrial Systems (Finland)

    2004-04-01

    The report describes a simple comparison of two CCF-models, the ECLM, and the Beta-model. The objective of the comparison is to identify differences in the results of the models by applying the models in some simple test data cases. The comparison focuses mainly on theoretical aspects of the above mentioned CCF-models. The properties of the model parameter estimates in the data cases is also discussed. The practical aspects in using and estimating CCFmodels in real PSA context (e.g. the data interpretation, properties of computer tools, the model documentation) are not discussed in the report. Similarly, the qualitative CCF-analyses needed in using the models are not discussed in the report. (au)

  19. Chip Multithreaded Consistency Model

    Institute of Scientific and Technical Information of China (English)

    Zu-Song Li; Dan-Dan Huan; Wei-Wu Hu; Zhi-Min Tang

    2008-01-01

    Multithreaded technique is the developing trend of high performance processor. Memory consistency model is essential to the correctness, performance and complexity of multithreaded processor. The chip multithreaded consistency model adapting to multithreaded processor is proposed in this paper. The restriction imposed on memory event ordering by chip multithreaded consistency is presented and formalized. With the idea of critical cycle built by Wei-Wu Hu, we prove that the proposed chip multithreaded consistency model satisfies the criterion of correct execution of sequential consistency model. Chip multithreaded consistency model provides a way of achieving high performance compared with sequential consistency model and ensures the compatibility of software that the execution result in multithreaded processor is the same as the execution result in uniprocessor. The implementation strategy of chip multithreaded consistency model in Godson-2 SMT processor is also proposed. Godson-2 SMT processor supports chip multithreaded consistency model correctly by exception scheme based on the sequential memory access queue of each thread.

  20. Models (Part 1).

    Science.gov (United States)

    Callison, Daniel

    2002-01-01

    Defines models and describes information search models that can be helpful to instructional media specialists in meeting users' abilities and information needs. Explains pathfinders and Kuhlthau's information search process, including the pre-writing information search process. (LRW)

  1. Modeling DNA Replication.

    Science.gov (United States)

    Bennett, Joan

    1998-01-01

    Recommends the use of a model of DNA made out of Velcro to help students visualize the steps of DNA replication. Includes a materials list, construction directions, and details of the demonstration using the model parts. (DDR)

  2. Modeling Complex Time Limits

    Directory of Open Access Journals (Sweden)

    Oleg Svatos

    2013-01-01

    Full Text Available In this paper we analyze complexity of time limits we can find especially in regulated processes of public administration. First we review the most popular process modeling languages. There is defined an example scenario based on the current Czech legislature which is then captured in discussed process modeling languages. Analysis shows that the contemporary process modeling languages support capturing of the time limit only partially. This causes troubles to analysts and unnecessary complexity of the models. Upon unsatisfying results of the contemporary process modeling languages we analyze the complexity of the time limits in greater detail and outline lifecycles of a time limit using the multiple dynamic generalizations pattern. As an alternative to the popular process modeling languages there is presented PSD process modeling language, which supports the defined lifecycles of a time limit natively and therefore allows keeping the models simple and easy to understand.

  3. World Magnetic Model 2010

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The World Magnetic Model is the standard model used by the U.S. Department of Defense, the U.K. Ministry of Defence, the North Atlantic Treaty Organization (NATO)...

  4. Bounding Species Distribution Models

    Science.gov (United States)

    Stohlgren, Thomas J.; Jarnevich, Cahterine S.; Morisette, Jeffrey T.; Esaias, Wayne E.

    2011-01-01

    Species distribution models are increasing in popularity for mapping suitable habitat for species of management concern. Many investigators now recognize that extrapolations of these models with geographic information systems (GIS) might be sensitive to the environmental bounds of the data used in their development, yet there is no recommended best practice for "clamping" model extrapolations. We relied on two commonly used modeling approaches: classification and regression tree (CART) and maximum entropy (Maxent) models, and we tested a simple alteration of the model extrapolations, bounding extrapolations to the maximum and minimum values of primary environmental predictors, to provide a more realistic map of suitable habitat of hybridized Africanized honey bees in the southwestern United States. Findings suggest that multiple models of bounding, and the most conservative bounding of species distribution models, like those presented here, should probably replace the unbounded or loosely bounded techniques currently used [Current Zoology 57 (5): 642-647, 2011].

  5. The ATLAS Analysis Model

    CERN Multimedia

    Amir Farbin

    The ATLAS Analysis Model is a continually developing vision of how to reconcile physics analysis requirements with the ATLAS offline software and computing model constraints. In the past year this vision has influenced the evolution of the ATLAS Event Data Model, the Athena software framework, and physics analysis tools. These developments, along with the October Analysis Model Workshop and the planning for CSC analyses have led to a rapid refinement of the ATLAS Analysis Model in the past few months. This article introduces some of the relevant issues and presents the current vision of the future ATLAS Analysis Model. Event Data Model The ATLAS Event Data Model (EDM) consists of several levels of details, each targeted for a specific set of tasks. For example the Event Summary Data (ESD) stores calorimeter cells and tracking system hits thereby permitting many calibration and alignment tasks, but will be only accessible at particular computing sites with potentially large latency. In contrast, the Analysis...

  6. LAT Background Models

    Data.gov (United States)

    National Aeronautics and Space Administration — The Galactic model is a spatial and spectral template. The model for the Galactic diffuse emission was developed using spectral line surveys of HI and CO (as a...

  7. Photovoltaic sources modeling

    CERN Document Server

    Petrone, Giovanni; Spagnuolo, Giovanni

    2016-01-01

    This comprehensive guide surveys all available models for simulating a photovoltaic (PV) generator at different levels of granularity, from cell to system level, in uniform as well as in mismatched conditions. Providing a thorough comparison among the models, engineers have all the elements needed to choose the right PV array model for specific applications or environmental conditions matched with the model of the electronic circuit used to maximize the PV power production.

  8. Toric models of graphs

    CERN Document Server

    Buczyńska, Weronika

    2010-01-01

    We define toric projective model of a trivalent graph as a generalization of a binary symmetric model of a trivalent phylogenetic tree. Generators of the projective coordinate ring of the models of graphs with one cycle are explicitly described. The models of graphs with the same topological invariants are deformation equivalent and share the same Hilbert function. We also provide an algorithm to compute the Hilbert function.

  9. Model of magnetostrictive actuator

    Institute of Scientific and Technical Information of China (English)

    LI Lin; ZHANG Yuan-yuan

    2005-01-01

    The hysteresis of the magnetostrictive actuator was studied. A mathematical model of the hysteresis loop was obtained on the basis of experiment. This model depends on the frequency and the amplitude of the alternating current inputted to the magnetostrictive actuator. Based on the model, the effect of hysteresis on dynamic output of the magnetostrictive actuator was investigated. Then how to consider hysteresis and establish a dynamic model of a magnetostrictive actuator system is discussed when a practical system was designed and applied.

  10. GIS Conceptual Data Model

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    In order to set up a conceptual data model that reflects the real world as accurately as possible,this paper firstly reviews and analyzes the disadvantages of previous conceptual data models used by traditional GIS in simulating geographic space,gives a new explanation to geographic space and analyzes its various essential characteristics.Finally,this paper proposes several detailed key points for designing a new type of GIS data model and gives a simple holistic GIS data model.

  11. Modeling Digital Video Database

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    The main purpose of the model is to present how the UnifiedModeling L anguage (UML) can be used for modeling digital video database system (VDBS). It demonstrates the modeling process that can be followed during the analysis phase of complex applications. In order to guarantee the continuity mapping of the mo dels, the authors propose some suggestions to transform the use case diagrams in to an object diagram, which is one of the main diagrams for the next development phases.

  12. Hierarchical Bass model

    Science.gov (United States)

    Tashiro, Tohru

    2014-03-01

    We propose a new model about diffusion of a product which includes a memory of how many adopters or advertisements a non-adopter met, where (non-)adopters mean people (not) possessing the product. This effect is lacking in the Bass model. As an application, we utilize the model to fit the iPod sales data, and so the better agreement is obtained than the Bass model.

  13. Quantal Response: Nonparametric Modeling

    Science.gov (United States)

    2017-01-01

    spline N−spline Fig. 3 Logistic regression 7 Approved for public release; distribution is unlimited. 5. Nonparametric QR Models Nonparametric linear ...stimulus and probability of response. The Generalized Linear Model approach does not make use of the limit distribution but allows arbitrary functional...7. Conclusions and Recommendations 18 8. References 19 Appendix A. The Linear Model 21 Appendix B. The Generalized Linear Model 33 Appendix C. B

  14. Auxiliary Deep Generative Models

    OpenAIRE

    Maaløe, Lars; Sønderby, Casper Kaae; Sønderby, Søren Kaae; Winther, Ole

    2016-01-01

    Deep generative models parameterized by neural networks have recently achieved state-of-the-art performance in unsupervised and semi-supervised learning. We extend deep generative models with auxiliary variables which improves the variational approximation. The auxiliary variables leave the generative model unchanged but make the variational distribution more expressive. Inspired by the structure of the auxiliary variable we also propose a model with two stochastic layers and skip connections...

  15. Avionics Architecture Modelling Language

    Science.gov (United States)

    Alana, Elena; Naranjo, Hector; Valencia, Raul; Medina, Alberto; Honvault, Christophe; Rugina, Ana; Panunzia, Marco; Dellandrea, Brice; Garcia, Gerald

    2014-08-01

    This paper presents the ESA AAML (Avionics Architecture Modelling Language) study, which aimed at advancing the avionics engineering practices towards a model-based approach by (i) identifying and prioritising the avionics-relevant analyses, (ii) specifying the modelling language features necessary to support the identified analyses, and (iii) recommending/prototyping software tooling to demonstrate the automation of the selected analyses based on a modelling language and compliant with the defined specification.

  16. Hierarchical Bass model

    CERN Document Server

    Tashiro, Tohru

    2013-01-01

    We propose a new model about diffusion of a product which includes a memory of how many adopters or advertisements a non-adopter met, where (non-)adopters mean people (not) possessing the product. This effect is lacking in the Bass model. As an application, we utilize the model to fit the iPod sales data, and so the better agreement is obtained than the Bass model.

  17. Artificial neural network modelling

    CERN Document Server

    Samarasinghe, Sandhya

    2016-01-01

    This book covers theoretical aspects as well as recent innovative applications of Artificial Neural networks (ANNs) in natural, environmental, biological, social, industrial and automated systems. It presents recent results of ANNs in modelling small, large and complex systems under three categories, namely, 1) Networks, Structure Optimisation, Robustness and Stochasticity 2) Advances in Modelling Biological and Environmental Systems and 3) Advances in Modelling Social and Economic Systems. The book aims at serving undergraduates, postgraduates and researchers in ANN computational modelling. .

  18. Optimization modeling with spreadsheets

    CERN Document Server

    Baker, Kenneth R

    2015-01-01

    An accessible introduction to optimization analysis using spreadsheets Updated and revised, Optimization Modeling with Spreadsheets, Third Edition emphasizes model building skills in optimization analysis. By emphasizing both spreadsheet modeling and optimization tools in the freely available Microsoft® Office Excel® Solver, the book illustrates how to find solutions to real-world optimization problems without needing additional specialized software. The Third Edition includes many practical applications of optimization models as well as a systematic framework that il

  19. Model Checking Feature Interactions

    DEFF Research Database (Denmark)

    Le Guilly, Thibaut; Olsen, Petur; Pedersen, Thomas;

    2015-01-01

    This paper presents an offline approach to analyzing feature interactions in embedded systems. The approach consists of a systematic process to gather the necessary information about system components and their models. The model is first specified in terms of predicates, before being refined to t...... to timed automata. The consistency of the model is verified at different development stages, and the correct linkage between the predicates and their semantic model is checked. The approach is illustrated on a use case from home automation....

  20. GARCH Modelling of Cryptocurrencies

    Directory of Open Access Journals (Sweden)

    Jeffrey Chu

    2017-10-01

    Full Text Available With the exception of Bitcoin, there appears to be little or no literature on GARCH modelling of cryptocurrencies. This paper provides the first GARCH modelling of the seven most popular cryptocurrencies. Twelve GARCH models are fitted to each cryptocurrency, and their fits are assessed in terms of five criteria. Conclusions are drawn on the best fitting models, forecasts and acceptability of value at risk estimates.

  1. Modelling of Corrosion Cracks

    DEFF Research Database (Denmark)

    Thoft-Christensen, Palle

    Modelling of corrosion cracking of reinforced concrete structures is complicated as a great number of uncertain factors are involved. To get a reliable modelling a physical and mechanical understanding of the process behind corrosion in needed.......Modelling of corrosion cracking of reinforced concrete structures is complicated as a great number of uncertain factors are involved. To get a reliable modelling a physical and mechanical understanding of the process behind corrosion in needed....

  2. Modeling and Remodeling Writing

    Science.gov (United States)

    Hayes, John R.

    2012-01-01

    In Section 1 of this article, the author discusses the succession of models of adult writing that he and his colleagues have proposed from 1980 to the present. He notes the most important changes that differentiate earlier and later models and discusses reasons for the changes. In Section 2, he describes his recent efforts to model young…

  3. Climate models and scenarios

    Energy Technology Data Exchange (ETDEWEB)

    Fortelius, C.; Holopainen, E.; Kaurola, J.; Ruosteenoja, K.; Raeisaenen, J. [Helsinki Univ. (Finland). Dept. of Meteorology

    1996-12-31

    In recent years the modelling of interannual climate variability has been studied, the atmospheric energy and water cycles, and climate simulations with the ECHAM3 model. In addition, the climate simulations of several models have been compared with special emphasis in the area of northern Europe

  4. Crushed Salt Constitutive Model

    Energy Technology Data Exchange (ETDEWEB)

    Callahan, G.D.

    1999-02-01

    The constitutive model used to describe the deformation of crushed salt is presented in this report. Two mechanisms -- dislocation creep and grain boundary diffusional pressure solution -- are combined to form the basis for the constitutive model governing the deformation of crushed salt. The constitutive model is generalized to represent three-dimensional states of stress. Upon complete consolidation, the crushed-salt model reproduces the Multimechanism Deformation (M-D) model typically used for the Waste Isolation Pilot Plant (WIPP) host geological formation salt. New shear consolidation tests are combined with an existing database that includes hydrostatic consolidation and shear consolidation tests conducted on WIPP and southeastern New Mexico salt. Nonlinear least-squares model fitting to the database produced two sets of material parameter values for the model -- one for the shear consolidation tests and one for a combination of the shear and hydrostatic consolidation tests. Using the parameter values determined from the fitted database, the constitutive model is validated against constant strain-rate tests. Shaft seal problems are analyzed to demonstrate model-predicted consolidation of the shaft seal crushed-salt component. Based on the fitting statistics, the ability of the model to predict the test data, and the ability of the model to predict load paths and test data outside of the fitted database, the model appears to capture the creep consolidation behavior of crushed salt reasonably well.

  5. Modeling EERE Deployment Programs

    Energy Technology Data Exchange (ETDEWEB)

    Cort, K. A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Hostick, D. J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Belzer, D. B. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Livingston, O. V. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2007-11-01

    This report compiles information and conclusions gathered as part of the “Modeling EERE Deployment Programs” project. The purpose of the project was to identify and characterize the modeling of deployment programs within the EERE Technology Development (TD) programs, address possible improvements to the modeling process, and note gaps in knowledge in which future research is needed.

  6. Modelling Vocabulary Loss

    Science.gov (United States)

    Meara, Paul

    2004-01-01

    This paper describes some simple simulation models of vocabulary attrition. The attrition process is modelled using a random autonomous Boolean network model, and some parallels with real attrition data are drawn. The paper argues that applying a complex systems approach to attrition can provide some important insights, which suggest that real…

  7. Flexible survival regression modelling

    DEFF Research Database (Denmark)

    Cortese, Giuliana; Scheike, Thomas H; Martinussen, Torben

    2009-01-01

    Regression analysis of survival data, and more generally event history data, is typically based on Cox's regression model. We here review some recent methodology, focusing on the limitations of Cox's regression model. The key limitation is that the model is not well suited to represent time-varyi...

  8. Scalability of human models

    NARCIS (Netherlands)

    Rodarius, C.; Rooij, L. van; Lange, R. de

    2007-01-01

    The objective of this work was to create a scalable human occupant model that allows adaptation of human models with respect to size, weight and several mechanical parameters. Therefore, for the first time two scalable facet human models were developed in MADYMO. First, a scalable human male was

  9. Modeling typical performance measures

    NARCIS (Netherlands)

    Weekers, Anke Martine

    2009-01-01

    In the educational, employment, and clinical context, attitude and personality inventories are used to measure typical performance traits. Statistical models are applied to obtain latent trait estimates. Often the same statistical models as the models used in maximum performance measurement are appl

  10. Model-based geostatistics

    CERN Document Server

    Diggle, Peter J

    2007-01-01

    Model-based geostatistics refers to the application of general statistical principles of modeling and inference to geostatistical problems. This volume provides a treatment of model-based geostatistics and emphasizes on statistical methods and applications. It also features analyses of datasets from a range of scientific contexts.

  11. Zephyr - the prediction models

    DEFF Research Database (Denmark)

    Nielsen, Torben Skov; Madsen, Henrik; Nielsen, Henrik Aalborg

    2001-01-01

    This paper briefly describes new models and methods for predicationg the wind power output from wind farms. The system is being developed in a project which has the research organization Risø and the department of Informatics and Mathematical Modelling (IMM) as the modelling team and all the Dani...

  12. Model Breaking Points Conceptualized

    Science.gov (United States)

    Vig, Rozy; Murray, Eileen; Star, Jon R.

    2014-01-01

    Current curriculum initiatives (e.g., National Governors Association Center for Best Practices and Council of Chief State School Officers 2010) advocate that models be used in the mathematics classroom. However, despite their apparent promise, there comes a point when models break, a point in the mathematical problem space where the model cannot,…

  13. Generalized Poisson sigma models

    CERN Document Server

    Batalin, I; Batalin, Igor; Marnelius, Robert

    2001-01-01

    A general master action in terms of superfields is given which generates generalized Poisson sigma models by means of a natural ghost number prescription. The simplest representation is the sigma model considered by Cattaneo and Felder. For Dirac brackets considerably more general models are generated.

  14. Modern Media Education Models

    Science.gov (United States)

    Fedorov, Alexander

    2011-01-01

    The author supposed that media education models can be divided into the following groups: (1) educational-information models (the study of the theory, history, language of media culture, etc.), based on the cultural, aesthetic, semiotic, socio-cultural theories of media education; (2) educational-ethical models (the study of moral, religions,…

  15. Models for Products

    Science.gov (United States)

    Speiser, Bob; Walter, Chuck

    2011-01-01

    This paper explores how models can support productive thinking. For us a model is a "thing", a tool to help make sense of something. We restrict attention to specific models for whole-number multiplication, hence the wording of the title. They support evolving thinking in large measure through the ways their users redesign them. They assume new…

  16. Genome-Scale Models

    DEFF Research Database (Denmark)

    Bergdahl, Basti; Sonnenschein, Nikolaus; Machado, Daniel

    2016-01-01

    An introduction to genome-scale models, how to build and use them, will be given in this chapter. Genome-scale models have become an important part of systems biology and metabolic engineering, and are increasingly used in research, both in academica and in industry, both for modeling chemical pr...

  17. Rock Properties Model

    Energy Technology Data Exchange (ETDEWEB)

    C. Lum

    2004-09-16

    The purpose of this model report is to document the Rock Properties Model version 3.1 with regard to input data, model methods, assumptions, uncertainties and limitations of model results, and qualification status of the model. The report also documents the differences between the current and previous versions and validation of the model. The rock properties model provides mean matrix and lithophysae porosity, and the cross-correlated mean bulk density as direct input to the ''Saturated Zone Flow and Transport Model Abstraction'', MDL-NBS-HS-000021, REV 02 (BSC 2004 [DIRS 170042]). The constraints, caveats, and limitations associated with this model are discussed in Section 6.6 and 8.2. Model validation accomplished by corroboration with data not cited as direct input is discussed in Section 7. The revision of this model report was performed as part of activities being conducted under the ''Technical Work Plan for: The Integrated Site Model, Revision 05'' (BSC 2004 [DIRS 169635]). The purpose of this revision is to bring the report up to current procedural requirements and address the Regulatory Integration Team evaluation comments. The work plan describes the scope, objectives, tasks, methodology, and procedures for this process.

  18. Deep Stochastic Radar Models

    OpenAIRE

    Wheeler, Tim Allan; Holder, Martin; Winner, Hermann; Kochenderfer, Mykel

    2017-01-01

    Accurate simulation and validation of advanced driver assistance systems requires accurate sensor models. Modeling automotive radar is complicated by effects such as multipath reflections, interference, reflective surfaces, discrete cells, and attenuation. Detailed radar simulations based on physical principles exist but are computationally intractable for realistic automotive scenes. This paper describes a methodology for the construction of stochastic automotive radar models based on deep l...

  19. Bioeconomic and market models

    Science.gov (United States)

    Richard Haynes; Darius Adams; Peter Ince; John Mills; Ralph Alig

    2006-01-01

    The United States has a century of experience with the development of models that describe markets for forest products and trends in resource conditions. In the last four decades, increasing rigor in policy debates has stimulated the development of models to support policy analysis. Increasingly, research has evolved (often relying on computer-based models) to increase...

  20. Model Breaking Points Conceptualized

    Science.gov (United States)

    Vig, Rozy; Murray, Eileen; Star, Jon R.

    2014-01-01

    Current curriculum initiatives (e.g., National Governors Association Center for Best Practices and Council of Chief State School Officers 2010) advocate that models be used in the mathematics classroom. However, despite their apparent promise, there comes a point when models break, a point in the mathematical problem space where the model cannot,…

  1. A Model Performance

    Science.gov (United States)

    Thornton, Bradley D.; Smalley, Robert A.

    2008-01-01

    Building information modeling (BIM) uses three-dimensional modeling concepts, information technology and interoperable software to design, construct and operate a facility. However, BIM can be more than a tool for virtual modeling--it can provide schools with a 3-D walkthrough of a project while it still is on the electronic drawing board. BIM can…

  2. Model Rockets and Microchips.

    Science.gov (United States)

    Fitzsimmons, Charles P.

    1986-01-01

    Points out the instructional applications and program possibilities of a unit on model rocketry. Describes the ways that microcomputers can assist in model rocket design and in problem calculations. Provides a descriptive listing of model rocket software for the Apple II microcomputer. (ML)

  3. Dynamic term structure models

    DEFF Research Database (Denmark)

    Andreasen, Martin Møller; Meldrum, Andrew

    This paper studies whether dynamic term structure models for US nominal bond yields should enforce the zero lower bound by a quadratic policy rate or a shadow rate specification. We address the question by estimating quadratic term structure models (QTSMs) and shadow rate models with at most four...

  4. Modelling: Nature and Use

    DEFF Research Database (Denmark)

    2011-01-01

    Engineering of products and processes is increasingly “model-centric”. Models in their multitudinous forms are ubiquitous, being heavily used for a range of decision making activities across all life cycle phases. This chapter gives an overview of what is a model, the principal activities in the ...

  5. Simplicial chiral models

    CERN Document Server

    Rossi, P; Rossi, Paolo; Tan, Chung I

    1995-01-01

    Principal chiral models on a d-1 dimensional simplex are introduced and studied analytically in the large N limit. The d = 0 , 2, 4 and \\infty models are explicitly solved. Relationship with standard lattice models and with few-matrix systems in the double scaling limit are discussed.

  6. Cellular therapies in trauma and critical care medicine: Looking towards the future.

    Directory of Open Access Journals (Sweden)

    Shibani Pati

    2017-07-01

    Full Text Available Shibani Pati and Todd Rasmussen summarize progress in preclinical research on cellular therapeutics for traumatic injury and its sequelae and discuss prospects for clinical translation.

  7. Rootsi suursaadik tänas eestlasi kaastunde eest / Dag Hartelius ; interv. Andri Maimets

    Index Scriptorium Estoniae

    Hartelius, Dag

    2003-01-01

    Intervjuu Rootsi suursaadikuga Eestis Dag Harteliusega mõrvatud Rootsi välisministrist Anna Lindhist ja poliitikute turvalisuse tagamisest. Kommenteerivad: Anders Fogh Rasmussen, Kristiina Ojuland, Igor Ivanov

  8. Key issues for mountain areas

    National Research Council Canada - National Science Library

    Price, Martin F; Jansky, Libor; Iatsenia, Andrei A

    2004-01-01

    ... and livelihood opportunities . . . ... Safdar Parvez and Stephen F. Rasmussen 86 6 Mountain tourism and the conservation of biological and cultural diversity... Wendy Brewer Lama and Nikhat Sattar 11...

  9. Modeling agriculture in the Community Land Model

    Directory of Open Access Journals (Sweden)

    B. Drewniak

    2013-04-01

    Full Text Available The potential impact of climate change on agriculture is uncertain. In addition, agriculture could influence above- and below-ground carbon storage. Development of models that represent agriculture is necessary to address these impacts. We have developed an approach to integrate agriculture representations for three crop types – maize, soybean, and spring wheat – into the coupled carbon–nitrogen version of the Community Land Model (CLM, to help address these questions. Here we present the new model, CLM-Crop, validated against observations from two AmeriFlux sites in the United States, planted with maize and soybean. Seasonal carbon fluxes compared well with field measurements for soybean, but not as well for maize. CLM-Crop yields were comparable with observations in countries such as the United States, Argentina, and China, although the generality of the crop model and its lack of technology and irrigation made direct comparison difficult. CLM-Crop was compared against the standard CLM3.5, which simulates crops as grass. The comparison showed improvement in gross primary productivity in regions where crops are the dominant vegetation cover. Crop yields and productivity were negatively correlated with temperature and positively correlated with precipitation, in agreement with other modeling studies. In case studies with the new crop model looking at impacts of residue management and planting date on crop yield, we found that increased residue returned to the litter pool increased crop yield, while reduced residue returns resulted in yield decreases. Using climate controls to signal planting date caused different responses in different crops. Maize and soybean had opposite reactions: when low temperature threshold resulted in early planting, maize responded with a loss of yield, but soybean yields increased. Our improvements in CLM demonstrate a new capability in the model – simulating agriculture in a realistic way, complete with

  10. Mechanics of materials model

    Science.gov (United States)

    Meister, Jeffrey P.

    1987-01-01

    The Mechanics of Materials Model (MOMM) is a three-dimensional inelastic structural analysis code for use as an early design stage tool for hot section components. MOMM is a stiffness method finite element code that uses a network of beams to characterize component behavior. The MOMM contains three material models to account for inelastic material behavior. These include the simplified material model, which assumes a bilinear stress-strain response; the state-of-the-art model, which utilizes the classical elastic-plastic-creep strain decomposition; and Walker's viscoplastic model, which accounts for the interaction between creep and plasticity that occurs under cyclic loading conditions.

  11. Integrated ELM modelling

    Energy Technology Data Exchange (ETDEWEB)

    Loennroth, J.S.; Kiviniemi, T. [Association EURATOM-Tekes, Helsinki University of Technology, P. O. Box 4100, 02015 TKK (Finland); Bateman, G.; Kritz, A. [Lehigh University, Bethlehem, PA (United States); Becoulet, M.; Figarella, C.; Garbet, X.; Huysmans, G. [Association Euratom-CEA, CEA Cadarache (France); Beyer, P. [University of Marseille (France); Corrigan, G.; Fundamenski, W. [UKAEA Fusion Association, Culham Science Centre (United Kingdom); Garcia, O.E.; Naulin, V. [Association Euratom-Risoe National Laboratory, Roskilde (Denmark); Janeschitz, G. [Forschungszentrum Karlsruhe (Germany); Johnson, T. [Association Euratom-VR, Royal Institute of Technology, Stockholm (Sweden); Kuhn, S. [Association Euratom-OeAW, University of Innsbruck (Austria); Loarte, A. [EFDA Close Support Unit, Garching (Germany); Nave, F. [Association Euratom-IST, Centro de Fusao Nuclear, Lisbon (Portugal); Onjun, T. [Sirindhorn International Institute of Technology (Thailand); Pacher, G.W. [Hydro Quebec (Canada); Pacher, H.D.; Pankin, A.; Parail, V.; Pitts, R.; Saibene, G.; Snyder, P.; Spence, J.; Tskhakaya, D.; Wilson, H.

    2006-09-15

    This paper presents a short overview of current trends and progress in integrated ELM modelling. First, the concept of integrated ELM modelling is introduced, various interpretations of it are given and the need for it is discussed. Then follows an overview of different techniques and methods used in integrated ELM modelling presented roughly according to physics approached in use and in order of increasing complexity. The paper concludes with a short discussion of open issues and future modelling requirements within the field of integrated ELM modelling. (copyright 2006 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)

  12. CRAC2 model description

    Energy Technology Data Exchange (ETDEWEB)

    Ritchie, L.T.; Alpert, D.J.; Burke, R.P.; Johnson, J.D.; Ostmeyer, R.M.; Aldrich, D.C.; Blond, R.M.

    1984-03-01

    The CRAC2 computer code is a revised version of CRAC (Calculation of Reactor Accident Consequences) which was developed for the Reactor Safety Study. This document provides an overview of the CRAC2 code and a description of each of the models used. Significant improvements incorporated into CRAC2 include an improved weather sequence sampling technique, a new evacuation model, and new output capabilities. In addition, refinements have been made to the atmospheric transport and deposition model. Details of the modeling differences between CRAC2 and CRAC are emphasized in the model descriptions.

  13. Validated dynamic flow model

    DEFF Research Database (Denmark)

    Knudsen, Torben

    2011-01-01

    The purpose with this deliverable 2.5 is to use fresh experimental data for validation and selection of a flow model to be used for control design in WP3-4. Initially the idea was to investigate the models developed in WP2. However, in the project it was agreed to include and focus on a additive...... model turns out not to be useful for prediction of the flow. Moreover, standard Box Jenkins model structures and multiple output auto regressive models proves to be superior as they can give useful predictions of the flow....

  14. UZ Colloid Transport Model

    Energy Technology Data Exchange (ETDEWEB)

    M. McGraw

    2000-04-13

    The UZ Colloid Transport model development plan states that the objective of this Analysis/Model Report (AMR) is to document the development of a model for simulating unsaturated colloid transport. This objective includes the following: (1) use of a process level model to evaluate the potential mechanisms for colloid transport at Yucca Mountain; (2) Provide ranges of parameters for significant colloid transport processes to Performance Assessment (PA) for the unsaturated zone (UZ); (3) Provide a basis for development of an abstracted model for use in PA calculations.

  15. Auxiliary Deep Generative Models

    DEFF Research Database (Denmark)

    Maaløe, Lars; Sønderby, Casper Kaae; Sønderby, Søren Kaae;

    2016-01-01

    Deep generative models parameterized by neural networks have recently achieved state-of-the-art performance in unsupervised and semi-supervised learning. We extend deep generative models with auxiliary variables which improves the variational approximation. The auxiliary variables leave...... the generative model unchanged but make the variational distribution more expressive. Inspired by the structure of the auxiliary variable we also propose a model with two stochastic layers and skip connections. Our findings suggest that more expressive and properly specified deep generative models converge...

  16. Transgenesis for pig models

    Science.gov (United States)

    Yum, Soo-Young; Yoon, Ki-Young; Lee, Choong-Il; Lee, Byeong-Chun

    2016-01-01

    Animal models, particularly pigs, have come to play an important role in translational biomedical research. There have been many pig models with genetically modifications via somatic cell nuclear transfer (SCNT). However, because most transgenic pigs have been produced by random integration to date, the necessity for more exact gene-mutated models using recombinase based conditional gene expression like mice has been raised. Currently, advanced genome-editing technologies enable us to generate specific gene-deleted and -inserted pig models. In the future, the development of pig models with gene editing technologies could be a valuable resource for biomedical research. PMID:27030199

  17. Process modeling style

    CERN Document Server

    Long, John

    2014-01-01

    Process Modeling Style focuses on other aspects of process modeling beyond notation that are very important to practitioners. Many people who model processes focus on the specific notation used to create their drawings. While that is important, there are many other aspects to modeling, such as naming, creating identifiers, descriptions, interfaces, patterns, and creating useful process documentation. Experience author John Long focuses on those non-notational aspects of modeling, which practitioners will find invaluable. Gives solid advice for creating roles, work produ

  18. Modeling Epidemic Network Failures

    DEFF Research Database (Denmark)

    Ruepp, Sarah Renée; Fagertun, Anna Manolova

    2013-01-01

    the SID model’s behavior and impact on the network performance, as well as the severity of the infection spreading. The simulations are carried out in OPNET Modeler. The model provides an important input to epidemic connection recovery mechanisms, and can due to its flexibility and versatility be used......This paper presents the implementation of a failure propagation model for transport networks when multiple failures occur resulting in an epidemic. We model the Susceptible Infected Disabled (SID) epidemic model and validate it by comparing it to analytical solutions. Furthermore, we evaluate...

  19. Modeling Epidemic Network Failures

    DEFF Research Database (Denmark)

    Ruepp, Sarah Renée; Fagertun, Anna Manolova

    2013-01-01

    This paper presents the implementation of a failure propagation model for transport networks when multiple failures occur resulting in an epidemic. We model the Susceptible Infected Disabled (SID) epidemic model and validate it by comparing it to analytical solutions. Furthermore, we evaluate...... the SID model’s behavior and impact on the network performance, as well as the severity of the infection spreading. The simulations are carried out in OPNET Modeler. The model provides an important input to epidemic connection recovery mechanisms, and can due to its flexibility and versatility be used...... to evaluate multiple epidemic scenarios in various network types....

  20. Models of Goldstone gauginos

    Science.gov (United States)

    Alves, Daniele S. M.; Galloway, Jamison; McCullough, Matthew; Weiner, Neal

    2016-04-01

    Models with Dirac gauginos are appealing scenarios for physics beyond the Standard Model. They have smaller radiative corrections to scalar soft masses, a suppression of certain supersymmetry (SUSY) production processes at the LHC, and ameliorated flavor constraints. Unfortunately, they are generically plagued by tachyons charged under the Standard Model, and attempts to eliminate such states typically spoil the positive features. The recently proposed "Goldstone gaugino" mechanism provides a simple realization of Dirac gauginos that is automatically free of dangerous tachyonic states. We provide details on this mechanism and explore models for its origin. In particular, we find SUSY QCD models that realize this idea simply and discuss scenarios for unification.