Sample records for model palle rasmussen
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DEFF Research Database (Denmark)
Ougaard, Morten
2015-01-01
En svaghed ved Kasper Lippert-Rasmussens i øvrigt udmærkede bog om Erik Rasmussen er, at den forbigår den sene Rasmussens bog om komplementaritet og statskundskab. Bogen var vigtig for Rasmussen, og den bør indgå i hans faglige eftermæle. Den rummer videnskabsteoretiske argumenter af stor relevans...... ikke mindst forholdet mellem normative og kognitive udsagn. Efter mødet med Niels Bohrs filosofi står Rasmussens værdirelativisme både skarpere og stærkere end før, og Kasper Lippert-Rasmussens karakteristik af denne position som et ubegrundet dogme i dansk politologi er ikke overbevisende....
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Rasmussen's legacy: A paradigm change in engineering for safety.
Leveson, Nancy G
2017-03-01
This paper describes three applications of Rasmussen's idea to systems engineering practice. The first is the application of the abstraction hierarchy to engineering specifications, particularly requirements specification. The second is the use of Rasmussen's ideas in safety modeling and analysis to create a new, more powerful type of accident causation model that extends traditional models to better handle human-operated, software-intensive, sociotechnical systems. Because this new model has a formal, mathematical foundation built on systems theory (as was Rasmussen's original model), new modeling and analysis tools become possible. The third application is to engineering hazard analysis. Engineers have traditionally either omitted human from consideration in system hazard analysis or have treated them rather superficially, for example, that they behave randomly. Applying Rasmussen's model of human error to a powerful new hazard analysis technique allows human behavior to be included in engineering hazard analysis. Copyright © 2016 Elsevier Ltd. All rights reserved.
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Rasmussen's model of human behavior in laparoscopy training.
Wentink, M; Stassen, L P S; Alwayn, I; Hosman, R J A W; Stassen, H G
2003-08-01
Compared to aviation, where virtual reality (VR) training has been standardized and simulators have proven their benefits, the objectives, needs, and means of VR training in minimally invasive surgery (MIS) still have to be established. The aim of the study presented is to introduce Rasmussen's model of human behavior as a practical framework for the definition of the training objectives, needs, and means in MIS. Rasmussen distinguishes three levels of human behavior: skill-, rule-, and knowledge-based behaviour. The training needs of a laparoscopic novice can be determined by identifying the specific skill-, rule-, and knowledge-based behavior that is required for performing safe laparoscopy. Future objectives of VR laparoscopy trainers should address all three levels of behavior. Although most commercially available simulators for laparoscopy aim at training skill-based behavior, especially the training of knowledge-based behavior during complications in surgery will improve safety levels. However, the cost and complexity of a training means increases when the training objectives proceed from the training of skill-based behavior to the training of complex knowledge-based behavior. In aviation, human behavior models have been used successfully to integrate the training of skill-, rule-, and knowledge-based behavior in a full flight simulator. Understanding surgeon behavior is one of the first steps towards a future full-scale laparoscopy simulator.
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Multiphasic presentation of Rasmussen's encephalitis
Avbersek, A.; Miserocchi, A.; McEvoy, A.W.; Patel, A.V.; Aronica, E.; Blumcke, I.; Jacques, T.S.; Acheson, J.; Thom, M.; Sisodiya, S.M.
2015-01-01
Rasmussen's encephalitis is a rare, chronic inflammatory disorder of unknown cause, characterised by drug-resistant focal epilepsy that may rarely present in adolescence or adulthood. We present a case of Rasmussen's encephalitis with prominent recurrent fluctuation in symptoms and well-documented
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Adult-onset Rasmussen encephalitis associated with focal cortical dysplasia.
Hohenbichler, Katharina; Lelotte, Julie; Lhommel, Renaud; Tahry, Riëm El; Vrielynck, Pascal; Santos, Susana Ferrao
2017-12-01
Rasmussen encephalitis is a rare, devastating condition, typically presenting in childhood. Cases of adult-onset Rasmussen have also been described, but the clinical picture is less defined, rendering final diagnosis difficult. We present a case of adult-onset Rasmussen encephalitis with dual pathology, associated with focal cortical dysplasia and encephalitis. We interpreted the Rasmussen encephalitis to be caused by severe and continuous epileptic activity due to focal cortical dysplasia. The best therapeutic approach for such cases remains unclear.
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Education, Learning and Development in the Periphery
DEFF Research Database (Denmark)
Rasmussen, Palle
2012-01-01
Palle Rasmussens artikkel handler om utdannelse, læring og utvikling i utkantområder, belyst gjennom utdanningens rolle i den regionale utviklingen i Danmark. Rasmussen peker på at Danmark har et velutviklet utdanningssystem som sikrer en relativt lik fordeling av befolkningens utdanningsmulighet...
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Situational and Demographic Factors in the Sudden Growth of Pall Mall, 2002-2014.
Sharma, Anushree; Fix, Brian V; Delnevo, Cristine D; Cummings, K Michael; O'Connor, Richard J
2018-05-03
Pall Mall gained significant brand share in the cigarette market between 2002 and 2013. We sought to determine whether demographic shifts occurred among the participants reporting Pall Mall as their usual brand during this time span. We examined National Survey of Drug Use and Health (NSDUH) data from 2002-2014. Demographic characteristics included age, education, ethnicity, income, and cigarette use (cigarettes per day, daily/non-daily smoking, and nicotine dependence). We also examined RJ Reynolds investor reports and shareholder documents to determine the impact of tobacco marketing on the growth of Pall Mall. Over 2002-2014, Pall Mall has gained among smokers 26 to 34 years of age. More Pall Mall smokers in 2014 report higher incomes (over $75000), and also report lower scores on measures of cigarette dependence, compared to 2002. Pall Mall smokers over time seem to share characteristics of premium cigarette brands smokers. The profile of the typical Pall Mall smoker has changed as the brand has gained market share. An association exists between brand positioning and economic forces, which has contributed to an increase in the market share for Pall Mall. It is well known that cigarette marketing drives the sale of tobacco products. The growth in the market share of Pall Mall serves as an excellent example to demonstrate how economic uncertainty paired with brand positioning and advertising worked together to serve as a catalyst for the rapid growth observed for this brand. This paper also looked at various demographic changes that occurred among Pall Mall smokers over a 12 year period and compared them to smokers of all other cigarette brands. The results of this analysis demonstrate the importance of monitoring trends over time among cigarette smokers.
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Rehabilitation for the Rasmussen report: conscientious and honest work
International Nuclear Information System (INIS)
Apold, A.
1979-01-01
It is pointed out that claims recently made from anti-nuclear sources that the Lewis Committee condemned the Rasmussen report as being unuseable in the evaluation of nuclear safety are untrue. In support of this the report of the Lewis Committee, Rasmussen's rejoinder and personal statements by Lewis are quoted. (JIW)
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Rasmussen's encephalitis presenting as focal cortical dysplasia
O'Rourke, D.J.; Bergin, A.; Rotenberg, A.; Peters, J.; Gorman, M.; Poduri, A.; Cryan, J.; Lidov, H.; Madsen, J.; Harini, C.
2014-01-01
Rasmussen's encephalitis is a rare syndrome characterized by intractable seizures, often associated with epilepsia partialis continua and symptoms of progressive hemispheric dysfunction. Seizures are usually the hallmark of presentation, but antiepileptic drug treatment fails in most patients and is ineffective against epilepsia partialis continua, which often requires surgical intervention. Co-occurrence of focal cortical dysplasia has only rarely been described and may have implications regarding pathophysiology and management. We describe a rare case of dual pathology of Rasmussen's encephalitis presenting as a focal cortical dysplasia (FCD) and discuss the literature on this topic. PMID:25667877
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Personalising e-learning modules: targeting Rasmussen levels using XML.
Renard, J M; Leroy, S; Camus, H; Picavet, M; Beuscart, R
2003-01-01
The development of Internet technologies has made it possible to increase the number and the diversity of on-line resources for teachers and students. Initiatives like the French-speaking Virtual Medical University Project (UMVF) try to organise the access to these resources. But both teachers and students are working on a partly redundant subset of knowledge. From the analysis of some French courses we propose a model for knowledge organisation derived from Rasmussen's stepladder. In the context of decision-making Rasmussen has identified skill-based, rule-based and knowledge-based levels for the mental process. In the medical context of problem-solving, we apply these three levels to the definition of three students levels: beginners, intermediate-level learners, experts. Based on our model, we build a representation of the hierarchical structure of data using XML language. We use XSLT Transformation Language in order to filter relevant data according to student level and to propose an appropriate display on students' terminal. The model and the XML implementation we define help to design tools for building personalised e-learning modules.
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Effect of elevated natural radioactivity on the bone marrow morphology of Microtus oeconomus Pall
Energy Technology Data Exchange (ETDEWEB)
Materii, L D; Maslova, K I
1984-03-01
Distinctive aspects of the bone marrow morphology of the rodent Microtus oeconomus Pall are studied with respect to a level of natural alpha, beta, and gamma background radiation which is higher than normal. Microtus oeconomus Pall is found to exhibit focal myeloid and erythroid elements, and an increased number of caryocytes due to increased mitotic activity. It is suggested that the action of Microtus oeconomus Pall's hemopoesis is an evolutionary adaptation to the higher level of background radiation in the animal's environment. 10 references.
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Rasmussen's encephalitis presenting as focal cortical dysplasia
Directory of Open Access Journals (Sweden)
D.J. O'Rourke
2014-01-01
Full Text Available Rasmussen's encephalitis is a rare syndrome characterized by intractable seizures, often associated with epilepsia partialis continua and symptoms of progressive hemispheric dysfunction. Seizures are usually the hallmark of presentation, but antiepileptic drug treatment fails in most patients and is ineffective against epilepsia partialis continua, which often requires surgical intervention. Co-occurrence of focal cortical dysplasia has only rarely been described and may have implications regarding pathophysiology and management. We describe a rare case of dual pathology of Rasmussen's encephalitis presenting as a focal cortical dysplasia (FCD and discuss the literature on this topic.
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Ravindra, Vijay M; Mazur, Marcus D; Mohila, Carrie A; Sweney, Matthew T; Hersh, Aimee; Bollo, Robert J
2015-11-01
Rasmussen encephalitis without seizures is rare. We report a case of Rasmussen encephalitis and cortical dysplasia without epilepsy as well as describe the imaging, pathology, and clinical course and review the literature to investigate whether this may represent a rare subset of Rasmussen encephalitis. We report the case of a 12-year-old girl with a history of cognitive decline and right arm weakness. Magnetic resonance imaging demonstrated diffuse left hemispheric cortical and subcortical atrophy suggestive of Rasmussen encephalitis. The patient had no clinical history of seizures, and electroencephalography did not demonstrate epileptiform abnormalities. Craniotomy for open brain biopsy was performed, and histopathologic evaluation identified Rasmussen encephalitis with cortical dysplasia (dual pathology). To the best of our knowledge, this is the third case of Rasmussen encephalitis diagnosed by both imaging and histopathology that had no clinical or electroencephalographic evidence of seizures and is the only case of Rasmussen encephalitis with cortical dysplasia without epilepsy.
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Serial MRI and MRS studies with unusual findings in Rasmussen's encephalitis
International Nuclear Information System (INIS)
Tuerkdogan-Soezueer, D.; Oezek, M.M.; Pamir, M.N.; Sav, A.; Dincer, A.
2000-01-01
Rasmussen's syndrome is characterized by intractable seizures and progressive neuropsychiatric deterioration secondary to unilateral cortical inflammation and tissue destruction. Diagnosis of Rasmussen's syndrome in the early phase depends mainly on the clinical features. Neuroimaging and histopathologic examinations may not be specific during this period. We report a case of Rasmussen's syndrome followed by serial MRI and magnetic resonance spectroscopy (MRS) studies over a 3- to 16-month period. A healthy 6-year-old boy presented with focal motor seizures. An MRI study demonstrated prominent enlargement and T2 hyperintensity of the left mesial temporal lobe and perisylvian region. This early finding evolved to volume loss and later progressive atrophy of the ipsilateral hemisphere when epilepsia partialis continua occurred. Being aware of those early MRI features in a patient with increasing frequency of focal motor seizures should suggest Rasmussen's syndrome. In addition, we found prominently increased myoinositol concentration in atrophic cortex which might reflect increased gliosis in the late period of the disease. (orig.)
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Anti-N-Methyl-D-Aspartate Receptor Encephalitis and Rasmussen-like Syndrome: An Association?
Gurcharran, Kevin; Karkare, Shefali
2017-01-01
N-methyl-D-aspartate (NMDA) receptor encephalitis is an immune-mediated condition that has a broad spectrum of manifestations, including seizures, coma, psychosis, and focal neurological deficits. Although usually a diffuse process, unihemispheric involvement mimicking early stages of Rasmussen encephalitis can occur. Rasmussen's encephalitis is a unique syndrome characterized by progressive hemiplegia, drug-resistant focal epilepsy, cognitive decline, and hemispheric brain atrophy contralateral to the hemiplegia. We describe a two-year-old girl with progressive right weakness and epilepsia partialis continua, concerning for early Rasmussen's encephalitis, who tested positive for anti-NMDA receptor antibodies. She experienced complete clinical recovery after immunotherapy. Anti-NMDA receptor antibodies were absent at three weeks and again at one year after the first treatment of intravenous immunoglobulin. There are few reports of Rasmussen-like encephalitis in individuals with anti-NMDA receptor antibody positivity. Thus the clinical significance of this association is yet to be determined. In addition, several other antibodies have been documented in individuals with Rasmussen encephalitis. The lack of a consistently reported antibody in Rasmussen encephalitis patients and the temporary nature of the anti-NMDA receptor antibody in our patient raise the following question: Is the presence of anti-NMDA receptor antibodies the cause of the symptoms or secondary to the pathogenic process? Copyright © 2016 Elsevier Inc. All rights reserved.
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Jia, Na; Li, Yuwen; Wu, Yin; Xi, Miaomiao; Hur, Gangmin; Zhang, Xinxin; Cui, Jia; Sun, Wenji; Wen, Aidong
2012-12-18
Tibetan medicine get used to use the flowers of Gentiana straminea Maxim. to cure inflammation of stomach and intestines, hepatitis, cholecystitis, etc. The flowers of Gentiana macrophylla Pall. have been traditionally treated as an anti-inflammatory agent to clear heat in Mongolian medicine. In traditional Chinese medicine, Gentiana macrophylla Pall. and Gentiana straminea Maxim. have also been used under the name "Gentianae Macrophyllae Radix" and prescribed for the treatment of pain and inflammatory conditions. The present study evaluated the pharmacological effects of two species of "Radix Gentianae Macrophyllae" in experimental inflammation and pain models, and determined the chemical compounds that may correlate with their pharmacological activities. The comparison is needed to identify whether the two related plants can be used interchangeably. We evaluated the pharmacological effects of the flowers of Gentiana macrophylla Pall. and Gentiana straminea Maxim. in experimental inflammation and pain models. An HPLC-MS method was developed to analyze the chemical composition. The effects of Gentiana macrophylla Pall. and Gentiana straminea Maxim. on the p65 and p50 phosphorylation were examined by immunblotting. NF-κB transcriptional activity was measured using the luciferase assay, in vitro kinase assay and Griess reaction. The extracts of Gentiana macrophylla Pall. and Gentiana straminea Maxim. possessed significant antinociceptive and anti-inflammatory activities. Flavonoids, secoiridoid glycosides and triterpines were determined in the extracts and may be the basis of the observed pharmacological effects. Nuclear translocation of p65, p50 and NF-κB transcriptional activity induced by LPS were suppressed by Gentiana macrophylla Pall. and Gentiana straminea Maxim. The results clearly demonstrated that the chemical composition and pharmacological activities of the two herbs were similar, which support the interchangeability among the two herbs when using them
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DEFF Research Database (Denmark)
Thorborg, Christoffer
2016-01-01
The present project attempts to articulate architecturally the psychic content in the danish graphic artist and draftsman Palle Nielsen's oeuvre. The museum inscribes itself within the city of Copenhagen as a part of it, but simultaneously establishes a taut vacuum between the city's buildings......, thereby setting these existing, surrounding monumental buildings in relief. The interior of the museum manifests itself as a dramatic, labyrinthine course of empty spaces, within which the visitor is deprived of contact with the city, and potentially loses his or her sense of place....
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Serial MRI and MRS studies with unusual findings in Rasmussen's encephalitis
Energy Technology Data Exchange (ETDEWEB)
Tuerkdogan-Soezueer, D. [Department of Pediatric Neurology, Institute of Neurological Sciences, Marmara University, Istanbul (Turkey); Oezek, M.M.; Pamir, M.N. [Department of Neurosurgery, Institute of Neurological Sciences, Marmara University, Istanbul (Turkey); Sav, A. [Department of Pathology, Institute of Neurological Sciences, Marmara University, Istanbul (Turkey); Dincer, A. [Radyomar MR Center, Istanbul (Turkey)
2000-06-01
Rasmussen's syndrome is characterized by intractable seizures and progressive neuropsychiatric deterioration secondary to unilateral cortical inflammation and tissue destruction. Diagnosis of Rasmussen's syndrome in the early phase depends mainly on the clinical features. Neuroimaging and histopathologic examinations may not be specific during this period. We report a case of Rasmussen's syndrome followed by serial MRI and magnetic resonance spectroscopy (MRS) studies over a 3- to 16-month period. A healthy 6-year-old boy presented with focal motor seizures. An MRI study demonstrated prominent enlargement and T2 hyperintensity of the left mesial temporal lobe and perisylvian region. This early finding evolved to volume loss and later progressive atrophy of the ipsilateral hemisphere when epilepsia partialis continua occurred. Being aware of those early MRI features in a patient with increasing frequency of focal motor seizures should suggest Rasmussen's syndrome. In addition, we found prominently increased myoinositol concentration in atrophic cortex which might reflect increased gliosis in the late period of the disease. (orig.)
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Directory of Open Access Journals (Sweden)
Andréia V. Faria
2009-09-01
Full Text Available Rasmussen's encephalitis is a devastating syndrome of multifocal brain dysfunction and focal seizures. Magnetic resonance (MR findings, associated with clinical data and electroencephalogram (EEG, may indicate the diagnosis and could be an indicative of prognosis. We studied 5 patients with Rasmussen's encephalitis, assessing clinical history and MR images. All patients had refractory focal seizures with a predominant motor component associated with hemispheric atrophy, that was proportional to severity of disease and neurological deficits in these patients. Gray and white matter abnormal signal on T2 MR images were found in patients who had hemiparesis. It was not related to the duration of the disease but to aggressiveness. MR proton spectroscopy in severe disease showed lactate and choline increase and decreased NAA, reflecting neuronal and axonal loss, gliosis and elevated membrane turnover and recent - crisis (not controlled. MR studies, in addition to help in diagnosis, may be useful for monitoring metabolic changes and progression of disease in Rasmussen's encephalitis.A encefalite de Rasmussen é uma devastadora síndrome com disfunção cerebral multifocal e convulsões focais. Achados de ressonância magnética (RM, associados aos dados clínicos e de eletrencefalograma (EEG, podem indicar o diagnóstico e podem ser indicativos de prognóstico. Foram estudados 5 pacientes com encefalite de Rasmussen, avaliando a história clínica e imagens de RM. Todos os pacientes apresentavam crises epilépticas focais refratárias com componente predominantemente motor associadas à atrofia hemisférica, que foi proporcional à gravidade da doença e déficits neurológicos nestes pacientes. Alteração da intensidade de sinal nas substâncias branca e cinzenta, nas sequências ponderadas em T2, foram encontradas nos pacientes com hemiparesia. Ela não estava relacionada com a duração da doença, mas à severidade. A espectroscopia de pr
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Prayson, Richard A
2012-01-01
Rasmussen's encephalitis is a well-established, albeit rare cause of medically intractable epilepsy. In a small number of Rasmussen's cases, a second pathology is identified, which independently can cause medically intractable seizures (dual pathology). This paper documents a case of a 13-year-old male who presented with medically intractable epilepsy. The patient underwent a series of surgical resections, early on resulting in a diagnosis of focal cortical dysplasia and later yielding a diagnosis of coexistent Rasmussen's encephalitis, marked by chronic inflammation, microglial nodules, and focal cortical atrophy, combined with focal cortical dysplasia (Palmini et al. type IIA, ILAE type IIA). The literature on dual pathology in the setting of Rasmussen's encephalitis is reviewed.
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Rasmussen's aneurysm: A rare and forgotten cause of hemoptysis
Directory of Open Access Journals (Sweden)
Rakesh Sapra
2015-12-01
Full Text Available Hemoptysis as a sequelae of past tubercular infection of lungs is a known occurrence. Hemoptysis in such a patient can result from a number of etiologies like tubercular reactivation, bronchiectasis, aspergiloma and vascular complications like hypervascularity from bronchial arteries, arteriovenous fistula formation, pseudoaneurysms, etc. Massive hemoptysis in such a patient is usually treated by bronchial artery embolization and occasionally by surgical lobectomy. A rare source of bleeding in such a patient is from Rasmussen's aneurysm arising from the pulmonary arteries. We report a young patient of treated pulmonary tuberculosis who had recurrent hemoptysis. He was treated earlier with bronchial artery embolization. On recurrence of hemoptysis, he was reevaluated and was found to have multiple Rasmussen's aneurysms arising from the pulmonary arteries, which were successfully treated by coil embolization.
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Anti-depressant effect of Paeonia lactiflora Pall extract in rats
African Journals Online (AJOL)
Anti-depressant effect of Paeonia lactiflora Pall extract in rats. Xiao-hui ... PLPE, at a dose ≥ 150 mg/kg significantly inhibited MAO A activity in rat whole brain in a dose-dependent manner .... (pH 7.4) upto a final volume of 1 ml. The reaction.
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Provável síndrome de Rasmussen: relato de caso
CORAL, LUÍZ CARLOS; HAAS, LEANDRO JOSÉ
1999-01-01
A síndrome de encefalite crônica com epilepsia (síndrome de Rasmussen) ocorre tipicamente em crianças e é caracterizada pelo desenvolvimento de epilepsia focal intratável, hemiparesia progressiva e deterioração intelectual. A etiologia é desconhecida e as anormalidades patológicas variam com a fase da doença. Relatamos o caso de um paciente jovem, com 17 anos de idade, com apresentação clínica da provável síndrome de Rasmussen. Discutimos a etiologia e o tratamento da patologia. The syndro...
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Provável síndrome de Rasmussen: relato de caso
Directory of Open Access Journals (Sweden)
CORAL LUÍZ CARLOS
1999-01-01
Full Text Available A síndrome de encefalite crônica com epilepsia (síndrome de Rasmussen ocorre tipicamente em crianças e é caracterizada pelo desenvolvimento de epilepsia focal intratável, hemiparesia progressiva e deterioração intelectual. A etiologia é desconhecida e as anormalidades patológicas variam com a fase da doença. Relatamos o caso de um paciente jovem, com 17 anos de idade, com apresentação clínica da provável síndrome de Rasmussen. Discutimos a etiologia e o tratamento da patologia.
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Recurring themes in the legacy of Jens Rasmussen
DEFF Research Database (Denmark)
Waterson, Patrick; Le Coze, Jean-Christophe; Andersen, Henning Boje
2016-01-01
The work of Jens Rasmussen over the course of the last half century represents some of the most influential contributions to the fields of cognitive science, human factors, ergonomics and safety science. His work has inspired researchers and practitioners in a number of fields including psycholog...
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Rasmussen's Aneurysm: A Forgotten Entity?
International Nuclear Information System (INIS)
Keeling, A. N.; Costello, R.; Lee, M. J.
2008-01-01
We present the case of a rare entity which is a complication of a disease process that had almost disappeared from the Western World. With the recent resurgence in reported cases of Mycobacterium tuberculosis (TB) in Western communities, it is important to recognize complications and sequelae. A young alcoholic male with confirmed active TB suffered a cardiac arrest following massive haemoptysis. Multidetector computed tomography angiography diagnosed a Rasmussen's aneurysm, confirmed by digital subtraction angiography and then successfully embolized with glue. We outline this rare case and the embolization technique and review previously documented reports
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Rasmussen's legacy and the long arm of rational choice.
Dekker, Sidney W A
2017-03-01
Rational choice theory says that operators and others make decisions by systematically and consciously weighing all possible outcomes along all relevant criteria. This paper first traces the long historical arm of rational choice thinking in the West to Judeo-Christian thinking, Calvin and Weber. It then presents a case study that illustrates the consequences of the ethic of rational choice and individual responsibility. It subsequently examines and contextualizes Rasmussen's legacy of pushing back against the long historical arm of rational choice, showing that bad outcomes are not the result of human immoral choice, but the product of normal interactions between people and systems. If we don't understand why people did what they did, Rasmussen suggested, it is not because people behaved inexplicably, but because we took the wrong perspective. Copyright © 2016 Elsevier Ltd. All rights reserved.
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DEFF Research Database (Denmark)
Andreasen, Karen Egedal; Rasmussen, Palle Damkjær; Ydesen, Christian
2016-01-01
Karen Egedal Andreasen, Palle Rasmussen and Christian Ydesen question in their article, how to guide youth in danger of being marginalised or excluded from society in general and the labour market in particular. They analyse the guidance dimension in the youth in development project as described ...... significant persons and guidance about educational system and possible jobs....
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Alkaloids from Mongolian species Berberis sibirica Pall
International Nuclear Information System (INIS)
Istatkova, R.; Philipov, S.; Tuleva, P.; Amgalan, A.; Samdan, J.; Dangaa, S.
2007-01-01
From the aerial parts of Berberis sibirica Pall. 6 isoquinoline alkaloids of protoberberine, protopine, benzphenanthridine and proaporphine type were isolated. The known alkaloids (-)-tetrahydropseudocoptisine, pseudoprotopine, (+)-chelidonine and (+)-glaziovine are new for the family Berberidaceae. From the roots of B. sibirica 10 isoquinoline alkaloids of protoberberine, benzylisoquinoline, bisbenzylisoquinoline, aporphine-benzylisoquinoline and proaporphine-benzylisoquinoline type were isolated. 1,10-Di-O-methylpakistanine has been reported for the first time as a natural alkaloid. The known alkaloids (-)-isothalidezine and (+)-armepavine have been found for the first time in the family Berberidaceae. All structures were determined by physical and spectral data. (authors)
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Functional hemispherotomy in Rasmussen syndrome in the absence of classic MRI findings
Directory of Open Access Journals (Sweden)
Yasunori Nagahama
2017-01-01
Full Text Available A 7-year-old previously healthy girl presented with a left-sided focal seizure without impaired consciousness and subsequently developed epilepsia partialis continua. Initial MRI was normal, and the subsequent images only showed a focal T2/FLAIR hyperintense area without cortical atrophy. She was diagnosed with Rasmussen syndrome by pathology and promptly treated with functional hemispherotomy. Rasmussen syndrome is a rare progressive neurological disorder, the only definitive cure for which is hemispheric disconnection. The disease presents a management dilemma, especially early in disease course without characteristic neuroimaging features. A high index of suspicion, multidisciplinary approach, and clear timely communication with the family are critical.
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International Nuclear Information System (INIS)
Paukert, J.
1986-01-01
Hairs of common hare (Lepus europaeus Pall.) and of common vole (Microtus arvalis Pall.) living in immission zones were investigated by INAA. Both the hare and the vole are almost exclusively herbivores; they consume relatively large amounts of contaminated food and reflect reliably the contamination degree of the respective ecosystem. The use of free-living animals for assessing environmental quality may complete effectively the information obtained by the examination of population. Though free-living animals lead a rather different way of existence it has been found that analyses of their hairs correlate very well with analyses of human hair. It may be expected that the changes in concentrations of heavy metals will manifest themselves earlier in animals than in men because the animals are strictly tied to local food sources. The hair samples of hares contained increased concentrations of Sm, La, Au, As, Se, Cr, Sc, Fe, Ce, Th and Co. The hairs of voles showed increased concentrations of Sm, La, Zn, As, Se, Cr, Sc, Fe, Sb, Ce, Cs and Co. A marked trend towards cumulation in hair was observed for the following elements: As, Se, Sc and Fe. The increase of their concentrations in the hairs of animals from the immission regions amounted to as much as 10 3 %. (author)
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Kant, Vivek
2017-03-01
Jens Rasmussen's contribution to the field of human factors and ergonomics has had a lasting impact. Six prominent interrelated themes can be extracted from his research between 1961 and 1986. These themes form the basis of an engineering epistemology which is best manifested by his abstraction hierarchy. Further, Rasmussen reformulated technical reliability using systems language to enable a proper human-machine fit. To understand the concept of human-machine fit, he included the operator as a central component in the system to enhance system safety. This change resulted in the application of a qualitative and categorical approach for human-machine interaction design. Finally, Rasmussen's insistence on a working philosophy of systems design as being a joint responsibility of operators and designers provided the basis for averting errors and ensuring safe and correct system functioning. Copyright © 2016 Elsevier Ltd. All rights reserved.
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ETV REPORT: REMOVAL OF ARSENIC IN DRINKING WATER - PALL CORPORATION MICROZA. MICROFILTRATION SYSTEM
Verification testing of the Pall Corporation Microza. Microfiltration System for arsenic removal was conducted at the Oakland County Drain Commissioner (OCDC) Plum Creek Development well station located in Oakland County, Michigan from August 19 through October 8, 2004. The sourc...
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Päike ja pall : [luuletused] / Ott Arder
Arder, Ott
2001-01-01
Sisu: Päike ja pall ; Õuna ja lõuna ; Kõige ilusam asi ; Emajõgi ; Väikemehe probleem ; Küünal ; Kapten ; Kaksteist kilu ja kaks teist kilu ; Suur ja seisev, ripub seinal ; Laul tagumisest vagunist ; Ultimaatum ; Ilus algus ; Pliiat(siga) ; Mure ja Amour ; kodust ja loomadest ; Eesli jõulupuu ; Aja saapad ; Lendav järv ; Unenäolaul ; Tere hommikust ja õhtust ; Kõik, mis juhtub ja ei juhtu ; Kas panna päkka või visata varvast ; Lihtne mees ; Väljaütlev ; Külm sõda ; Ohkav kruvi ; Metsa all ; Lauluke ; Unemetsades ; Suur rõõm ja väike mure ; Hea muusika ; Koer poiss ja plika ; Kes mängida veel ei oska ; Raske lumi ; Mere kaldal ; Unenäoukse taga
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What is the fate of disconnected brain tissue in a child with Rasmussen syndrome? A case report
Energy Technology Data Exchange (ETDEWEB)
Kim, S.J.; Park, Y.D. [Dept. of Neurology (Child), Medical Coll. of Georgia, Augusta, GA (United States); Pillai, J. [Dept. of Radiology, Medical Coll. of Georgia, Augusta, GA (United States)
2003-04-01
We describe a case of Rasmussen syndrome in a 7-year-old boy, presenting with epilepsia partialis continua, hemiplegia, and progressive mental deterioration. The initial MRI examination was normal, followed by progressive left hemispheric cortical atrophy and abnormal high signal intensity over the left occipital, parietal, and cingulate gyral areas over an 18-month period. On the basis of the clinical diagnosis and biopsy findings of Rasmussen syndrome, functional hemispherectomy was carried out at 7.5 years of age with alleviation of clinical seizures for the following 44 months. The follow-up MRI demonstrated atrophic changes involving the remaining left hemisphere with increased signal and cortical volume loss, as well as the absence of abnormal signal in the right hemisphere at 10 years of age. Our MRI findings are consistent with the progression of Rasmussen syndrome in the ipsilateral hemisphere even after functional-hemispherectomy without clinical seizures. (orig.)
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What is the fate of disconnected brain tissue in a child with Rasmussen syndrome? A case report
International Nuclear Information System (INIS)
Kim, S.J.; Park, Y.D.; Pillai, J.
2003-01-01
We describe a case of Rasmussen syndrome in a 7-year-old boy, presenting with epilepsia partialis continua, hemiplegia, and progressive mental deterioration. The initial MRI examination was normal, followed by progressive left hemispheric cortical atrophy and abnormal high signal intensity over the left occipital, parietal, and cingulate gyral areas over an 18-month period. On the basis of the clinical diagnosis and biopsy findings of Rasmussen syndrome, functional hemispherectomy was carried out at 7.5 years of age with alleviation of clinical seizures for the following 44 months. The follow-up MRI demonstrated atrophic changes involving the remaining left hemisphere with increased signal and cortical volume loss, as well as the absence of abnormal signal in the right hemisphere at 10 years of age. Our MRI findings are consistent with the progression of Rasmussen syndrome in the ipsilateral hemisphere even after functional-hemispherectomy without clinical seizures. (orig.)
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Doherty, Brooks
2016-01-01
Driven by faculty-based action research, redesigned residential and online courses, and changes to placement testing, Rasmussen College increased its developmental education pass rates by double digits while decreasing the number and percentage of students who require remedial coursework. Like many institutions of higher education, Rasmussen…
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The Pall/Kinetico Purefecta™ POU drinking water treatment system was tested for removal of aldicarb, benzene, cadmium, carbofuran, cesium, chloroform, dichlorvos, dicrotophos, fenamiphos, mercury, mevinphos, oxamyl, strontium, and strychnine. The Purefecta™ employs several compon...
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Phytochemical study on Berberis sibirica Pall.
Directory of Open Access Journals (Sweden)
A Solongo
2014-09-01
Full Text Available From the aerial parts (700g of berberis sibirica pall. 6 isoquinoline alkaloids of protoberberine, protopine, benzophenantridine and proaporphine type were isolated. The known alkaloids (--tetrahydropseudocoptisine, pseudoprotopine, (+-chelidonine and (+-glaziovine are new for the family berberidaceae. from the aerial part ii (3.9 kg 14 isoquinoline alkaloids of aporphine, proaporphine, protoberberine, protopine, benzylisoquinoline, bisbenzylisoquinoline,proaporphine-benzylisoquinoline and simple isoquinolin type were isolated and identified. The aporphine alkaloid 1-o-methylisotebaidine and simple isoquinoline dehydrocorypalline have been found for the first time in the family of berberidaceae. From the roots of b. sibirica 10 isoquinoline alkaloids of protoberberine, benzylisoquinoline, bisbenzylisoquinoline, aporphine-benzylisoquinoline and proaporphine-benzylisoquinoline type were isolated. 1,10-di-omethylpakistanine has been reported for the first time as a natural alkaloid. The known alkaloids (- -isothalidezine and (+-armepavine have been found for the first time in the family berberidaceae. All structures were determined by physical and spectral data.DOI: http://dx.doi.org/10.5564/mjc.v12i0.185 Mongolian Journal of Chemistry Vol.12 2011: 117-122
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International Nuclear Information System (INIS)
Borodkin, P.A.; Testov, B.V.
1980-01-01
The effect of low dose ionizing radiation on living organisms is studied. The blood of Clethrionomys rutilus Pall which habitates under various radioecological conditions is studied. It is taken into account that hematologic indices reflex the general state of the organism and prove to be a sensitive test of physiological alterations in the organism. The animals were taken on the territory with the increased amount of uranium and thorium in the underlying original rock. Average radiation doses from external gamma radiation on experimental and control territories constitute 0.86 and 0.1 rem/year, respectively. Radiation from thoron, radon and products of their decay condition the dose of 2 rem/year on the experimental territory and 0.1 rem/year on the control territory. Blood for investigation is taken with the method of decapitation. A 5% level of importance of differences is taken for the statistic processing of results obtained. The investigation has revealed no considerable differences between micropopulations of Clethrionomys rutilus Pall habitating different radioecological conditions over all indices of the red blood studied. As considers the composition of white blood, statistically considerable excess of the general amount of leukocytes in wintered males from the radioactive territory is found. An insignificant excess of this index has been noted in other groups of animals, as well
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The Rasmussen report - consequences and effects in consideration of the German situation
International Nuclear Information System (INIS)
Stoebel, W.
1976-01-01
The publication of the Rasmussen-report (WASH-1400) was the first to give an extensive analysis of severe reactor accidents and their consequences for the population. Despite all criticism in detail, the method of probabilistic analysis which was used here shows a way of more objective reporting and evaluation of the risks connected with nucleon engineering. Although the probability of the accidents cannot be easily transferred to German standards, the results of the report yet give rise to examine all possible cases of accident within the frame of safety analyses in order to be able to exlude a core meltdown with sufficient safety. The accident effects, which are, according to the report, less than thought until now, will be more unfavourable in our country because of the site conditions. The representation of the nuclear-technical risk as a total national risk shows a long distance to risks caused by natural phenomena or by engineering. The Rasmussen-report delivers arguments for supporters of nuclear energy; but it also admonishes of more carefulness by showing the complexity of the plants and the enormous variety of possible accidents. (orig.) [de
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International Nuclear Information System (INIS)
Krueger, F.W.
1976-06-01
The RASMUSSEN study represents an excellent survey of the current possibilities to assess quantitatively the operational risk of nuclear power plants. To close the big gaps which turned out to be still existent in calculating the possible accidents sequences and their consequences but also in the statistical materials, only rough models could be used because of the limited capability of theoretical analyses to replace lacking experience. Contrary to previous studies the risk estimates have not deliberately been maximized, apart from the fact that in many cases no 'safe' side does a priori exist. Rather, the RASMUSSEN study tried to make 'reasonable realistic' assumptions concerning accident sequences and activity release consequences, but it is difficult to refute that the results will tend to underestimate systematically the accident consequences. Besides, in every case the range of uncertainty will very likely be greater than stated in the study, not least also because the results are substantially influenced by technical features of the nuclear power plants under discussion. This should be given attention in discussions using the quantitative results of the study as well as the fact that planning, construction and operation of nuclear power plants must be done with utmost accuracy to achieve the specified low orders of risk. (author)
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Putaminal involvement in Rasmussen encephalitis
Energy Technology Data Exchange (ETDEWEB)
Rajesh, Bhagavatheeswaran; Ashalatha, Radhakrishnan [Sree Chitra Tirunal Institute for Medical Sciences and Technology, Department of Neurology, Trivandrum, Kerala (India); Kesavadas, Chandrasekharan; Thomas, Bejoy [Sree Chitra Tirunal Institute for Medical Sciences and Technology, Department of Imaging Sciences and Interventional Radiology, Trivandrum, Kerala (India)
2006-08-15
Rasmussen encephalitis (RE) is a rare devastating disease of childhood causing progressive neurological deficits and intractable seizures, typically affecting one hemisphere. Characteristic MRI features include progressive unihemispheric focal cortical atrophy and grey- or white-matter high-signal changes and basal ganglion involvement, particularly of the caudate nucleus. To analyse the pattern of involvement of different brain structures in a series of patients with RE and to attempt clinical correlation. We reviewed the medical records and neuroimaging data of 12 patients diagnosed with RE satisfying the European Consensus Statement diagnostic criteria. The disease manifested as seizures in all patients and was refractory; epilepsia partialis continua was a notable feature (nine patients). Hemiparesis of varying grades was noted in all but one patient; none had extrapyramidal signs. Neuroimaging showed cortical involvement in the insular/periinsular regions in 11 patients. Caudate atrophy was noted in ten patients. Putaminal atrophy was seen in nine patients, six of whom had additional hyperintense signal changes. Our study highlights frequent putaminal atrophy and signal changes in RE, which suggests a more extensive basal ganglion involvement than emphasized previously. Recognition of putaminal changes may be a useful additional tool in the radiological diagnosis of RE. (orig.)
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Putaminal involvement in Rasmussen encephalitis
International Nuclear Information System (INIS)
Rajesh, Bhagavatheeswaran; Ashalatha, Radhakrishnan; Kesavadas, Chandrasekharan; Thomas, Bejoy
2006-01-01
Rasmussen encephalitis (RE) is a rare devastating disease of childhood causing progressive neurological deficits and intractable seizures, typically affecting one hemisphere. Characteristic MRI features include progressive unihemispheric focal cortical atrophy and grey- or white-matter high-signal changes and basal ganglion involvement, particularly of the caudate nucleus. To analyse the pattern of involvement of different brain structures in a series of patients with RE and to attempt clinical correlation. We reviewed the medical records and neuroimaging data of 12 patients diagnosed with RE satisfying the European Consensus Statement diagnostic criteria. The disease manifested as seizures in all patients and was refractory; epilepsia partialis continua was a notable feature (nine patients). Hemiparesis of varying grades was noted in all but one patient; none had extrapyramidal signs. Neuroimaging showed cortical involvement in the insular/periinsular regions in 11 patients. Caudate atrophy was noted in ten patients. Putaminal atrophy was seen in nine patients, six of whom had additional hyperintense signal changes. Our study highlights frequent putaminal atrophy and signal changes in RE, which suggests a more extensive basal ganglion involvement than emphasized previously. Recognition of putaminal changes may be a useful additional tool in the radiological diagnosis of RE. (orig.)
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Energy Technology Data Exchange (ETDEWEB)
Matos, Adriana Silva; Goyanna, Fabiola; Gomes, Leo; Alexandre, Alexandre Kalil Castanheira; Rocha, Josilton Antonio; Souza, Paulo Engracio Matos de; Machado, Marcos; Santos, Marcelo Benicio dos [Hospital Sao Rafael, Salvador, BA (Brazil). Servico de Bioimagem
2000-04-01
The authors report a case of an 11-year-old boy with a Rasmussen aneurysm presenting with dyspnea, fever and hemoptysis. The patient underwent radiological, tomographic and angiographic assessments. The pathogenesis of the aneurysm was related to the erosion of a pulmonary artery branch with replacement of the adventitia and media layers by granulation tissue, due to an adjacent tuberculous cavity. A plain chest x-ray showed bilateral nodular opacities, largest on the right lung, which enhanced simultaneously with the mediastinal vessels on CT. Its vascular nature was confirmed by angiographic studies.(author)
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Antihyperlipidemic Activities of Common Garden Peony ( Paeonia lactifl ora Pall.
Directory of Open Access Journals (Sweden)
Tserenlkham Tserendejid
2013-12-01
Full Text Available We studied different extracts of aboveground and underground parts of Paeonia lactifl ora Pall.in experiment. For doing so this research needs to start up with total cholesterol. Total cholesterol is a direct cholesterol measurement that measures all cholesterol molecules in the blood, including low density lipoproteins (LDL, high density lipoproteins (HDL, and very low density lipoproteins (VLDL. The serum total cholesterol (TC and low density lipoproteins (LDL levels were signifi cantly different in the experimentally-induced hypercholesterolemia rats. Effect on serum triglyceride (TG level compared to control group, simvastatin and hypercholesterolemia diet (HD, but almost all were similar with simvastatin. Effect on serum high density lipoproteins (HDL level compared between those. Extracts (PL1, PL2 were lower, almost the same with hypercholesterolemia diet (HD.
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International Nuclear Information System (INIS)
Materij, L.D.; Maslova, K.I.
1984-01-01
In experiments on Microtus oeconomus Pall, living in natural conditions with normal (0.72-1.08 pA/kg) and increased (3.6-1440 pA/kg) levels of external gamma-radiation and affected by numerous incorporated radionuclides, the differences were detected, by the cytochemical method, both in the total glycogen content of eucocytes and in the type of grouping of cells depending on the cegre of their saturation with polysaccharide
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2011-03-01
... operation, a small support staging facility would be constructed at the active mining site immediately west... cooperating agency. The mining and reclamation plans have been developed and submitted for agency review of proposed open pit mining operations at the Rasmussen Valley Phosphate Federal Mineral Lease I-05975, in...
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Rasmussen aneurysm - a case report in a child and review of the literature
International Nuclear Information System (INIS)
Matos, Adriana Silva; Goyanna, Fabiola; Gomes, Leo; Alexandre, Alexandre Kalil Castanheira; Rocha, Josilton Antonio; Souza, Paulo Engracio Matos de; Machado, Marcos; Santos, Marcelo Benicio dos
2000-01-01
The authors report a case of an 11-year-old boy with a Rasmussen aneurysm presenting with dyspnea, fever and hemoptysis. The patient underwent radiological, tomographic and angiographic assessments. The pathogenesis of the aneurysm was related to the erosion of a pulmonary artery branch with replacement of the adventitia and media layers by granulation tissue, due to an adjacent tuberculous cavity. A plain chest x-ray showed bilateral nodular opacities, largest on the right lung, which enhanced simultaneously with the mediastinal vessels on CT. Its vascular nature was confirmed by angiographic studies. (author)
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Prayson, Richard A.
2012-01-01
Rasmussen’s encephalitis is a well-established, albeit rare cause of medically intractable epilepsy. In a small number of Rasmussen's cases, a second pathology is identified, which independently can cause medically intractable seizures (dual pathology). This paper documents a case of a 13-year-old male who presented with medically intractable epilepsy. The patient underwent a series of surgical resections, early on resulting in a diagnosis of focal cortical dysplasia and later yielding a diag...
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Directory of Open Access Journals (Sweden)
Yukitoshi Takahashi
2006-01-01
Full Text Available Rasmussen syndrome is an intractable epilepsy with a putative causal relation with cellular and humoral autoimmunity. Almost half of the patients have some preceding causative factors, with infections found in 38.2%, vaccinations in 5.9% and head trauma in 8.9% of Japanese patients. In a patient with seizure onset after influenza A infections, cross-reaction of the patient's lymphocytes with GluRε2 and influenza vaccine components was demonstrated by lymphocyte stimulation test. Database analyses revealed that influenza A virus hemagglutinin and GluRε2 molecules contain peptides with the patient's HLA class I binding motif (HLA ࢤ A*0201. The relative risks of HLA class I genotypes for Rasmussen syndrome are 6.1 (A*2402, 6.4 (A*0201, 6.3 (A*2601 and 11.4 (B*4601. The relative risks of HLA class I-A and B haplotypes are infinity (A*2601+B*5401, 21.1 (A*2402+B*1501, 13.3 (A*2402+B*4801 and 5.1 (A*2402+B*5201. Some alleles and haplotypes of HLA class I may be the risk factors in Japanese patients. Cross-reactivity of cytotoxic T lymphocytes may contribute to the processes leading from infection to the involvement of CNS.
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Atypical presentation in Rasmussen encephalitis: delayed late-onset periodic epileptic spasms.
Ferrari, Taíssa P F; Hamad, Ana P A; Caboclo, Luís Otávio S F; Centeno, Ricardo S; Zaninotto, Ana Luiza; Scattolin, Monica; Carrete Junior, Henrique; Lancellotti, Carmem L P; Yacubian, Elza Márcia T
2011-09-01
A five-and-a-half-year-old girl started experiencing progressive left hemiparesis at age two and a half years. At age five years and four months she started presenting clusters of asymmetric periodic epileptic spasms with no hypsarrhythmia. The ictal EEG showed periodic, constant and stereotyped complexes. Serial brain imaging revealed progressive atrophy of the right hemisphere with increased T2 signal on MRI. She underwent a right hemispherotomy, and histological examination showed signs of inflammation and features of focal cortical dysplasia (FCD). She has been seizure-free for 16 months. This case is unique in the following aspects: the presence of typical Rasmussen encephalitis features of progressive unilateral brain involvement without seizures, a delay of almost three years prior to seizure onset; an atypical seizure type presentation with periodic epileptic spasms and the presence of FCD associated with inflammatory changes. [Published with video sequences].
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Nuclear reactor safety, a review of the Rasmussen report (WASH -1400)
International Nuclear Information System (INIS)
Gilbert, C.P.
1979-03-01
The US Reactor Safety Study (WASH-1400), often referred to as RSS or the Rasmussen Report, sets out to estimate the risk to which the public is exposed by the possibility of an accident in one of the first 100 nuclear power stations situated in the USA. This review briefly describes the methods used in RSS, and indicates how the results were obtained. It then discusses the nature of these results, and the comparisons which RSS makes between them and other accident statistics. Finally, the criticisms which have been levelled at RSS are assessed, and the conclusions of a very recent US Nuclear Regulatory Commission review are included in appendix. RSS concludes that the risk due to reactor accidents is smaller than that associated with many other aspects of everyday life. While there are shortcomings in RSS, the author has little doubt that the above conclusion is valid
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Directory of Open Access Journals (Sweden)
Yu-Ting Liu
2018-01-01
Full Text Available Two new p-hydroxybenzoic acid glycosides, namely p-hydroxybenzoic acid-4-O-α-d-manopyranosyl-(1 → 3-α-l-rhamnopyranoside (compound 1 and 4-O-α-l-rhamnopyran-osyl-(1 → 6-α-d-manopyranosyl-(1 → 3-α-l-rhamnopyranoside (compound 2, and seven known compounds, compound 3, 6, 7 (acid components, compound 8, 9 (flavonoids, compound 4 (a coumarin and compound 5 (an alkaloid, were isolated from the 70% ethanol aqueous extract of the aerial parts of Melilotus officinalis (Linn. Pall. The structures of all compounds were elucidated by use of extensive spectroscopic methods Infrared Spectroscopy (IR, High resolution electrospray ionization mass spectrometry (HR-ESI-MS, and 1H and 13C-NMR. Sugar residues obtained after acid hydrolysis were identified by high-performance liquid chromatography (HPLC. The antioxidant activity of all the compounds was evaluated by 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid (ABTS+ and 1,1-diphenyl-2-picrylhydrazyl (DPPH. The anti-inflammatory effects of the compounds were also evaluated in lipopolysaccharide (LPS-stimulated RAW 264.7 macrophages. All compounds were shown to inhibit LPS-induced nitric oxide (NO and prostaglandin E 2 (PGE 2 production by suppressing the expression of inducible NO synthase (iNOS and cyclooxygenase-2 (COX-2, respectively, in LPS-stimulated RAW 264.7 cells. The inhibitory effect of all the compounds on MCF-7 cells was determined by Cell Counting Kit-8 (CCK-8 method. The results showed that compounds 1, 2, 7, 8, 9 exhibited better antioxidant activity compared to the other compounds. compounds 1–9 had different inhibitory effects on the release of NO, TNF-α and IL-6 in LPS-stimulated RAW264.7 cells by LPS, of which compound 7 was the most effective against inflammatory factors. compounds 1 and 2 have better antitumor activity compared to other compounds. Further research to elucidate the chemical composition and pharmacological effects of Melilotus officinalis (Linn. Pall is
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Approaches to gene pool conservation of medicinal plant Oxytropis lanata (Pall. DC. (Fabaceae
Directory of Open Access Journals (Sweden)
A. B. Kholina
2015-05-01
Full Text Available In order to preserve the gene pool of medicinal plant Oxytropis lanata (Pall. DC. we analyzed allozyme polymorphism and identified reliable and informative marker enzyme systems of this species; also we studied the response of seeds to deep freezing in liquid nitrogen (–196 ºС. Population has an average level of polymorphism (P95 = 41,2 %, P99 = 52,9 %, A = 1,58, Ho = 0,158, He = 0,171 in general typical for herbaceous legumes, and can serve as a source of material for gene pool conservation of the species. Deep freezing has not led to the death of the seeds; it was marked stimulatory effect of ultralow temperatures, expressed as an acceleration of germination and sharp increase of germinability (98,6 ± 2,3 % compared to the control (12,0 ± 3,5 % that is associated with overcoming physical dormancy. There were no abnormalities in the development of seedlings from seeds passed cryopreservation.
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Directory of Open Access Journals (Sweden)
Dong-Yi eHe
2011-02-01
Full Text Available In China, Korea and Japan, a decoction of the dried root without bark of Paeonia lactiflora Pall. has been used in the treatment of rheumatoid arthritis, systemic lupus erythematosus, hepatitis, dysmenorrhea, muscle cramping and spasms, and fever for more than 1200 years. A water/ethanol extract of the root is now known as total glucosides of paeony (TGP, which contains more than 15 components. Paeoniflorin is the most abundant ingredient and accounts for the pharmacological effects observed with TGP in both in vitro and in vivo studies. The analgesic effect of TGP was confirmed in various animal models of pain, which may be mediated partly by adenosine A1 receptor. The direct anti-inflammatory effects of TGP were observed in animal models of both acute and subacute inflammation, by inhibiting the production of prostaglandin E2, leukotrience B4, and nitric oxide, and by suppressing the increase of intracellular calcium ion concentration. TGP was also reported to have protective effects of cells against oxidative stress. In vitro, dual effects of TGP were noted on the proliferation of lymphocytes, differentiation of Th/Ts lymphocytes, and the production of pro-inflammatory cytokines and antibodies. In vivo, TGP inhibited the delayed-type hypersensitivity in immuno-activated mice, and enhanced the delayed-type hypersensitivity in immuno-suppressed mice. In adjuvant arthritis rats, paeoniflorin exerted immunosuppressive effects. The beneficial effects of TGP in treating rheumatoid arthritis were verified by randomized controlled trials. The adverse events of TGP were mainly gastrointestinal tract disturbances, mostly mild diarrhea.
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He, Dong-Yi; Dai, Sheng-Ming
2011-01-01
In China, Korea, and Japan, a decoction of the dried root without bark of Paeonia lactiflora Pall. has been used in the treatment of rheumatoid arthritis, systemic lupus erythematosus, hepatitis, dysmenorrhea, muscle cramping and spasms, and fever for more than 1200 years. A water/ethanol extract of the root is now known as total glucosides of peony (TGP), which contains more than 15 components. Paeoniflorin is the most abundant ingredient and accounts for the pharmacological effects observed with TGP in both in vitro and in vivo studies. The analgesic effect of TGP was confirmed in various animal models of pain, which may be mediated partly by adenosine A1 receptor. The direct anti-inflammatory effects of TGP were observed in animal models of both acute and subacute inflammation, by inhibiting the production of prostaglandin E2, leukotriene B4, and nitric oxide, and by suppressing the increase of intracellular calcium ion concentration. TGP was also reported to have protective effects of cells against oxidative stress. In vitro, dual effects of TGP were noted on the proliferation of lymphocytes, differentiation of Th/Ts lymphocytes, and the production of proinflammatory cytokines and antibodies. In vivo, TGP inhibited the delayed-type hypersensitivity in immuno-activated mice, and enhanced the delayed-type hypersensitivity in immuno-suppressed mice. In adjuvant arthritis rats, paeoniflorin exerted immunosuppressive effects. The beneficial effects of TGP in treating rheumatoid arthritis were verified by randomized controlled trials. The adverse events of TGP were mainly gastrointestinal tract disturbances, mostly mild diarrhea.
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Barrett, J; Dhurandhar, H N; Miller, E; Litwin, M S
1975-01-01
Experiments were performed to compare the effectiveness in vivo of the two most widely used micropore blood transfusion filters in preventing detrimental physiologic changes associated with transfusion of microaggregate-containing blood. Exchange transfusion with stored blood having an elevated screen filtration pressure (SFP) through polyester mesh (Pall) filters (Group PM) was followed by decreases in arterial blood pH and O2 consumption, increases in arterial blood pyruvate and lactate concentrations, and a decrease in pulmonary DO2. The lungs of 5 of 6 animals revealed emboli far out in the pulmonary microcirculation. These changes did not occur in animals transfused through dacron wool (Swank) filters (Group DW). Even though an increase after transfusion in pulmonary Qs/Qt in Group PM did not achieve statistical significance when compared to pretransfusion Qs/Qt, it was significantly higher than that in animals in Group DW. Both filters removed considerable quantities of microaggregates; however, the polyester mesh (Pall) filters permitted passage of small microaggregates and development of ditrimental physiologic changes. Dacron wool (Swank) filters completely removed measurable microaggregates and detrimental changes did not occur. Images Fig. 1. Fig. 2. Fig. 3. PMID:242282
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Nixon, Rhonda
2012-01-01
The author explores how comics texts and writing practices are rich literacy resources for educators. Few studies report on how teachers explore such texts and practices in their classrooms. The author examines how drawing improves students' narrative writing and presents findings from a 7-month case study of Delainey and Rasmussen's collaborative…
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International Nuclear Information System (INIS)
Chuang Chunyu; Lin Chiuhsiang Joe; Shiang Weijung; Hsieh Tsungling; Lioud Jinliang
2016-01-01
It is important to monitor operators' mental workload during the operation phase. Physiological measurement approaches could record the operator's mental data continuously, and might be less interruptive on the work activities. However, these methods often require the attachment of physical sensors, which are not unobtrusive in the physical sense. Furthermore, the individual difference makes calibrating to each individual tedious and requires trained persons to use. Often high noise-to-signal ratio data are hard to analyze. Due to these factors, physiological workload measurements are hardly widely applied in practical fields. In this study, an objective, non-intrusive and performance-based mental workload predictive model was proposed with high validity (R 2 = 0.51), which can be applied during the operation phrase. This model, developed based on the Rasmussen's skill–rule–knowledge framework, is comprised of two novel cognitive indices, the attention required index and uncertainty index. It can be used as the basis for establishing an early online warning system automatically. Furthermore, this model also predicts the types of error-prone tasks. This kind of information is expected to provide managers and supervisors with opportunities to intervene and improve tasks before error occurred. Finally, the predictive model proposed in this paper requires more practical application in fields to be completed. (author)
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FOCAL EPILEPTIC MYOCLONUS IN KOZHEVNIKOV–RASMUSSEN SYNDROME
Directory of Open Access Journals (Sweden)
N. E. Kvaskova
2016-01-01
Full Text Available The article presents the clinical, electroencephalographic (EEG and neuroimaging features, as well as the results of treatment of patients with focal epileptic myoclonus (FEM with the Kozhevnikov–Rasmussen syndrome (KRS. FEM in KRS-patients was identified in 11 cases, accounting for 0.9 % of all the cases of epilepsy with the onset of seizures up to 18 years (n = 1261. The age at onset of KRS ranged from 3 to 21 years (average – 9.2 ± 5.7 years. In the active period of the disease of all patients in the clinical picture the active FEM appeared and increasing frequency of the secondary generalized seizures (SGS. In addition SGS and FEM, the clinical picture of the disease in most patients (91 % the focal motor (clonic and the somatosensory focal seizures were observed. As the disease progressed, the FEM became more pronounced in frequency and intensity, seized more muscle groups, localizing mainly in the muscles of the trunk and limbs. The typical EEG pattern of FEM patients with KRS was regional epileptiform activity that occurs in the structure of the continued regional slowing localizing maximum of the fronto-central-temporal region. During the magnetic resonance tomography of the brain in dynamics all the patients observed the increase in total cortical hemiatrophy. In all the cases, the appointment of antiepileptic therapy resulted in a slowing of the FEM, however, a complete remission was reached at none of the patients. Two patients were made surgical treatment of epilepsy. In one case remission of epileptic seizures was observed after right-side hemispherotomy. Our study showed that FEM is very resistant type of epileptic seizures. This fact calls for the identification of the FEM at the early stages of the disease with the purpose to improve the prognosis, as well as for an earlier surgical treatment.
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DEFF Research Database (Denmark)
Faramarzi, Leila; Kontogeorgis, Georgios; Thomsen, Kaj
2009-01-01
The extended UNIQUAC model as proposed by Thomsen and Rasmussen [K. Thomsen, P. Rasmussen, Chem. Eng. Sci. 54 (1999) 1787-1802] was applied to the thermodynamic representation of carbon dioxide absorption in aqueous monoethanolamine (MEA) and methyldiethanolamine (MDEA) solutions. All the essential......-water systems in a wide range of temperature (-20-200 degrees C) were used. The application of the model to a large number of experimental data for representation of total pressure over the absorbent solutions (25-200 degrees C), correlation of the excess enthalpy and freezing point depression of the binary...
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The Root Extract of Gentiana macrophylla Pall. Alleviates Cardiac Apoptosis in Lupus Prone Mice.
Directory of Open Access Journals (Sweden)
Chih-Yang Huang
Full Text Available The roots of the perennial herb Gentiana macrophylla Pall. (GM are known as Qinjiao, which has been used for centuries to treat systemic lupus erythematosus (SLE. However, little is known about the effects of GM on cholesterol-aggravated cardiac abnormalities in SLE, and the mechanisms thereof. This study investigates whether GM exhibits anti-apoptotic effects, focusing on the left ventricle (LV of NZB/W F1 mice fed with high-cholesterol diet. The morphology and apoptotic status of ventricular tissues were determined by microscopy and Terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL assay. Levels of apoptotic biomarkers were determined by immunoblotting. The results thus obtained revealed that GM significantly reduced the cholesterol-aggravated apoptosis of LV in NZB/W F1 mice by suppressing both intrinsic and extrinsic apoptotic pathways. Additionally, GM significantly increased the cardiac insulin-like growth factors (IGF-1 survival signaling and anti-apoptotic proteins in LV tissues. Accordingly, GM is considered to be beneficial in alleviating cholesterol-aggravated cardiac damage in SLE, and therefore constitute an alternative treatment for SLE patients with cardiac abnormalities.
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Deng, Hui; Yan, Chunlin; Xiao, Tian; Yuan, Dingfen; Xu, Jinhua
2010-02-17
To evaluate the anti-angiogenesis effect of total glucosides of Paeonia lactiflora Pall. In this study, we determined the effect of TGP on the proliferation of human vascular endothelial cells through 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay and fluorescence-activated cell sorting analysis. A migration assay and a tube formation assay were used to investigate the migration properties and tube formation abilities of human vascular endothelial cells after being treated with TGP. Furthermore, the in vivo anti-angiogenic ability of TGP was determined through a chick chorioallantoic membrane assay. TGP (12.5, 62.5, and 312.5 microg/ml) resulted in a dose-dependent reduction in the proliferation of endothelial cells. This inhibition effect began 6h after treatment and lasted at least 24h. Fluorescence-activated cell sorting analysis data showed an accumulation of cells in the G0/G1 phase of the cell cycle, which exhibited apoptotic features indicative of cell death. The migration properties and tube forming abilities of endothelial cells were dramatically inhibited by the TGP extract. Our results show that TGP can inhibit angiogenesis in vitro and in vivo. Copyright 2009 Elsevier Ireland Ltd. All rights reserved.
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Rare event techniques applied in the Rasmussen study
International Nuclear Information System (INIS)
Vesely, W.E.
1977-01-01
The Rasmussen Study estimated public risks from commercial nuclear power plant accidents, and therefore the statistics of rare events had to be treated. Two types of rare events were specifically handled, those rare events which were probabilistically rare events and those which were statistically rare events. Four techniques were used to estimate probabilities of rare events. These techniques were aggregating data samples, discretizing ''continuous'' events, extrapolating from minor to catastrophic severities, and decomposing events using event trees and fault trees. In aggregating or combining data the goal was to enlarge the data sample so that the rare event was no longer rare, i.e., so that the enlarged data sample contained one or more occurrences of the event of interest. This aggregation gave rise to random variable treatments of failure rates, occurrence frequencies, and other characteristics estimated from data. This random variable treatment can be interpreted as being comparable to an empirical Bayes technique or a Bayesian technique. In the discretizing event technique, events of a detailed nature were grouped together into a grosser event for purposes of analysis as well as for data collection. The treatment of data characteristics as random variables helped to account for the uncertainties arising from this discretizing. In the severity extrapolation technique a severity variable was associated with each event occurrence for the purpose of predicting probabilities of catastrophic occurrences. Tail behaviors of distributions therefore needed to be considered. Finally, event trees and fault trees were used to express accident occurrences and system failures in terms of more basic events for which data existed. Common mode failures and general dependencies therefore needed to be treated. 2 figures
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DEFF Research Database (Denmark)
About the reconstruction of Palle Nielsen's (f. 1942) work The Model from 1968: a gigantic playground for children in the museum, where they can freely romp about, climb in ropes, crawl on wooden structures, work with tools, jump in foam rubber, paint with finger paints and dress up in costumes....
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DEFF Research Database (Denmark)
Faramarzi, Leila; Kontogeorgis, Georgios; Thomsen, Kaj
2009-01-01
The extended UNIQUAC model [K. Thomsen, R Rasmussen, Chem. Eng. Sci. 54 (1999) 1787-1802] was applied to the thermodynamic representation of carbon dioxide absorption in aqueous monoethanolamine (MEA), methyldiethanolamine (MDEA) and varied strength mixtures of the two alkanolamines (MEA-MDEA). F......The extended UNIQUAC model [K. Thomsen, R Rasmussen, Chem. Eng. Sci. 54 (1999) 1787-1802] was applied to the thermodynamic representation of carbon dioxide absorption in aqueous monoethanolamine (MEA), methyldiethanolamine (MDEA) and varied strength mixtures of the two alkanolamines (MEA......) are included in the parameter estimation process. The previously unavailable standard state properties of the alkanolamine ions appearing in this work, i.e. MEA protonate, MEA carbamate and MDEA protonate are determined. The concentration of the species in both MEA and MDEA solutions containing CO2...
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Dutova, S V; Karpova, M R; Myadelets, M A; Myasnaya, N V; Sherstoboev, E Yu
2015-01-01
A preclinical study of the immunocorrection action of the sum of active substances isolated from ethereal-oil plants Coluria geoides (Pall.) Ledeb. (Rosaceae family) with respect to experimental immunodeficiency showed that preparations relieve symptoms of immunodeficiency caused by the administration of cyclophosphan: suppressed synthesis of anti-erythrocyte antibodies (agglutinine) and proliferative processes in the spleen. Under the influence of C. geoides preparations, the absolute numbers of cariocytes and antibody forming cells in spleen significantly increased (compared to the group of animals with experimental immunodeficiency) and in some cases reached the background level. The drugs studied produced a more pronounced stimulating effect on the synthesis of specific immunoglobulins and proliferation of antibody forming cells of spleen as compared to the effect of Echinacea tincture. Preparation C-2 (extract from underground organs and grass of C. geoides obtained by percolation method with 70% ethanol) is most promising for in-depth research and the development of new effective drugs with immunocorrecting properties.
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International Nuclear Information System (INIS)
Keller, William; Modarres, Mohammad
2005-01-01
This paper reviews the historical development of the probabilistic risk assessment (PRA) methods and applications in the nuclear industry. A review of nuclear safety and regulatory developments in the early days of nuclear power in the United States has been presented. It is argued that due to technical difficulties for measuring and characterizing uncertainties and concerns over legal challenges, safety design and regulation of nuclear power plants has primarily relied upon conservative safety assessment methods derived based on a set of design and safety principles. Further, it is noted that the conservatism adopted in safety and design assessments has allowed the use of deterministic performance assessment methods. This approach worked successfully in the early years of nuclear power epoch as the reactor design proved to be safe enough. However, it has been observed that as the conservative approach to design and safety criteria proved arbitrary, and yielded inconsistencies in the degree to which different safety measures in nuclear power plants protect safety and public heath, the urge for a more consistent assessment of safety became apparent in the late 1960s. In the early 1970s, as a result of public and political pressures, then the US Atomic Energy Commission initiated a new look at the safety of the nuclear power plants through a comprehensive study called 'Reactor Safety Study' (WASH-1400, or 'Rasmussen Study'-after its charismatic study leader Professor Norman Rasmussen of MIT) to demonstrate safety of the nuclear power plants. Completed in October 1975, this landmark study introduced a novel probabilistic, systematic and holistic approach to the assessment of safety, which ultimately resulted in a sweeping paradigm shift in safety design and regulation of nuclear power in the United States in the turn of the Century. Technical issues of historic significance and concerns raised by the subsequent reviews of the Rasmussen Study have been discussed
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Modeling of carbon dioxide absorption by aqueous ammonia solutions using the Extended UNIQUAC model
DEFF Research Database (Denmark)
Darde, Victor Camille Alfred; van Well, Willy J. M.; Stenby, Erling Halfdan
2010-01-01
An upgraded version of the Extended UNIQUAC thermodynamic model for the carbon dioxide-ammonia-water system has been developed, based on the original version proposed by Thomsen and Rasmussen. The original model was valid in the temperature range 0-110°C, the pressure range 0-10 MPa...... properties of carbon dioxide and ammonia to supercritical conditions....
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Diagnostic imaging in 13 cases of Rasmussen's encephalitis. Can early MRI suggest the diagnosis?
International Nuclear Information System (INIS)
Chiapparini, L.; Farina, L.; Ciceri, E.; Erbetta, A.; Savoiardo, M.; Granata, T.; Ragona, F.; Freri, E.; Fusco, L.; Gobbi, G.; Capovilla, G.; Tassi, L.; Viri, M.; Giordano, L.; Bernardina, B.D.; Spreafico, R.
2003-01-01
Rasmussen's encephalitis (RE) is a rare, progressive, chronic encephalitis characterised by drug-resistant epilepsy, progressive hemiparesis and mental impairment. It typically involves only one cerebral hemisphere, which becomes atrophic. We present neuroradiological findings in 13 children with RE. MRI was performed in all patients, fluorodeoxyglucose positron-emission tomography (PET) in three, Tc-99m hexamethylpropylenamine oxime single-photon emission computed tomography (SPECT) in two and proton MR spectroscopy ( 1 HMRS) in two. MRI showed progression of the hemisphere atrophy, always prevalent in the region primarily involved (13 patients), spread of the abnormal signal in white matter (11) and cortex (10) and progression of atrophy of the head of the caudate nucleus (nine). Associated secondary changes were: atrophy of the contralateral cerebellar hemisphere (in four patients), the ipsilateral hippocampus (in five) and the brain stem (in five). The earliest CT and MRI abnormalities, seen between 1 day and 4 months after the first seizure (in 12 patients examined, nine of whom had MRI) in one cerebral hemisphere included: high signal on T2-weighted images in the cortex (seven patients) and white matter (nine), cortical atrophy usually involving the frontoinsular region, with mild or severe enlargement of the lateral ventricle (eight) and moderate atrophy of the head of the caudate nucleus (seven). (orig.)
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Some useful characteristics of performance models
International Nuclear Information System (INIS)
Worledge, D.H.
1985-01-01
This paper examines the demands placed upon models of human cognitive decision processes in application to Probabilistic Risk Assessment. Successful models, for this purpose, should, 1) be based on proven or plausible psychological knowledge, e.g., Rasmussen's mental schematic, 2) incorporate opportunities for slips, 3) take account of the recursive nature, in time, of corrections to mistaken actions, and 4) depend on the crew's predominant mental states that accompany such recursions. The latter is equivalent to an explicit coupling between input and output of Rasmussen's mental schematic. A family of such models is proposed with observable rate processes mediating the (conscious) mental states involved. It is expected that the cumulative probability distributions corresponding to the individual rate processes can be identified with probability-time correlations of the HCR Human Cognitive Reliability type discussed elsewhere in this session. The functional forms of the conditional rates are intuitively shown to have simple characteristics that lead to a strongly recursive stochastic process with significant predictive capability. Models of the type proposed have few parts and form a representation that is intentionally far short of a fully transparent exposition of the mental process in order to avoid making impossible demands on data
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Herbaceous Peony (Paeonia lactiflora Pall. as an Alternative Source of Oleanolic and Ursolic Acids
Directory of Open Access Journals (Sweden)
Jun Tao
2011-01-01
Full Text Available Oleanolic acid (OA and ursolic acid (UA have been proven to possess many biological activities, and much attention is focused on the search for plants which are rich in OA and UA. In this report, the OA and UA accumulation characteristics were investigated in 47 cultivars of Chinese herbaceous peony (Paeonia lactiflora Pall. and were followed in three cultivars over different developmental stages as measured by high performance liquid chromatography (HPLC. OA and UA levels in leaves and stems demonstrated an overall upward trend from May 1 to September 15 except for UA in the leaves of “Hong Feng”. The maximum values of OA and UA in leaves of “Yangfei Chu Yu”, “Fen Zhu Pan” and “Hong Feng” were 852.98, 575.60, 290.48 μg/g FW and 924.94, 827.36, 432.67 μg/g FW, respectively. The maximum values of OA and UA in stems of “Yangfei Chu Yu”, “Fen Zhu Pan” and “Hong Feng” were 359.28, 90.49, 43.90 μg/g FW and 326.86, 82.25, 56.63 μg/g FW, respectively. OA and UA contents in leaves of 47 different herbaceous peony cultivars ranged from 66.73–618.12 and 36.23–665.14 μg/g FW, respectively, with average values of 171.62 and 227.57 μg/g FW, respectively. The results suggested that the aboveground parts of herbaceous peony may be used as an alternative source of OA and UA for medicinal purposes in addition to its ornamental purposes.
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Ryuk, Jin Ah; Ko, Byoung-Seob; Lee, Hye Won; Kim, Da Sol; Kang, Suna; Lee, Yong Hyen; Park, Sunmin
2017-03-01
Tetragonia tetragonioides (Pall.) Kuntze (TTK) and JakYakGamCho-Tang (JGT) have been used for improving women's health and treating inflammatory diseases. We determined that the long-term consumption of these herbal extracts alleviates the progression of postmenopausal symptoms in high-fat-diet fed ovariectomized (OVX) rats, and further explored the mechanisms involved. Five groups of OVX rats were fed high fat diets that were supplemented with either 2% dextrin (control), 2% TTK (70% ethanol extract), 2% JGT (water extract), 1% JGT + 1% TTK (JGTT), or 30 µg/kg body weight/day of 17β-estradiol (positive control). After eight weeks of dietary intervention, the herbal treatments did not change the serum concentrations of 17β-estradiol or uterine weight in control rats, but they were higher in the positive-control group. TTK rats exhibited higher daily energy expenditure, particularly fat oxidation, without modifying the energy intake than the controls. TTK lowered the fat mass but lean body mass of the abdomen and leg were increased. JGT decreased periuterine fat mass and lean body mass more than the control but the decrease was not as much as TTK. TTK resulted in substantially lower serum concentrations of the proinflammatory cytokines, tumor necrosis factor-α (TNF-α) and monocyte chemoattractant protein-1, than the control and JGT had lesser effect than TTK. Insulin resistance, determined by homeostasis model assessment estimate for assessing insulin resistance (HOMA-IR) and insulin tolerance test, was reduced in the decreasing order of control, JGT, JGTT, and TTK and the HOMA-IR of TTK was similar to the positive control. TTK, but not JGT, enhanced glucose tolerance compared with the control, although the serum insulin levels in TTK were lower compared to the control. Interestingly, the β-cell masses were much greater in the TTK and JGTT groups than in the control, and they were comparable to the positive control. The increases in β-cell masses in TTK and
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Diagnostic imaging in 13 cases of Rasmussen's encephalitis. Can early MRI suggest the diagnosis?
Energy Technology Data Exchange (ETDEWEB)
Chiapparini, L.; Farina, L.; Ciceri, E.; Erbetta, A.; Savoiardo, M. [Dept. of Neuroradiology, Ist. Nazionale Neurologico ' ' C. Besta' ' , Milano (Italy); Granata, T.; Ragona, F.; Freri, E. [Dept. of Paediatric Neurology, Ist. Nazionale Neurologico ' ' C. Besta' ' , Milano (Italy); Fusco, L. [Dept. of Paediatric Neurology, Ospedale Pediatrico Bambino Gesu, Roma (Italy); Gobbi, G. [Dept. of Paediatric Neurology, Ospedale Maggiore Pizzardi, Bologna (Italy); Capovilla, G. [Dept. of Paediatric Neurology, Ospedale Poma, Mantova (Italy); Tassi, L. [Dept. of Epilepsy Surgery, Ospedale Niguarda Ca' Granda, Milano (Italy); Viri, M. [Epilepsy Centre, Ospedale Fatebenefratelli-Oftalmico, Milano (Italy); Giordano, L. [Dept. of Paediatric Neurology, Ospedale Civile, Brescia (Italy); Bernardina, B.D. [Dept. of Paediatric Neurology, Policlinico Borgo Roma, Verona (Italy); Spreafico, R. [Dept. of Neurophysiology, Ist. Nazionale Neurologico ' ' C. Besta' ' , Milano (Italy)
2003-03-01
Rasmussen's encephalitis (RE) is a rare, progressive, chronic encephalitis characterised by drug-resistant epilepsy, progressive hemiparesis and mental impairment. It typically involves only one cerebral hemisphere, which becomes atrophic. We present neuroradiological findings in 13 children with RE. MRI was performed in all patients, fluorodeoxyglucose positron-emission tomography (PET) in three, Tc-99m hexamethylpropylenamine oxime single-photon emission computed tomography (SPECT) in two and proton MR spectroscopy ({sup 1}HMRS) in two. MRI showed progression of the hemisphere atrophy, always prevalent in the region primarily involved (13 patients), spread of the abnormal signal in white matter (11) and cortex (10) and progression of atrophy of the head of the caudate nucleus (nine). Associated secondary changes were: atrophy of the contralateral cerebellar hemisphere (in four patients), the ipsilateral hippocampus (in five) and the brain stem (in five). The earliest CT and MRI abnormalities, seen between 1 day and 4 months after the first seizure (in 12 patients examined, nine of whom had MRI) in one cerebral hemisphere included: high signal on T2-weighted images in the cortex (seven patients) and white matter (nine), cortical atrophy usually involving the frontoinsular region, with mild or severe enlargement of the lateral ventricle (eight) and moderate atrophy of the head of the caudate nucleus (seven). (orig.)
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Garófalo-Gómez, Nicolás; Hamad, Ana P; Centeno, Ricardo S; Ferrari, Taíssa P; Carrete, Henrique; Caboclo, Luís O; Targas-Yacubian, Elza M
2013-02-16
Rasmussen's encephalitis (RE) is a progressive pathology affecting the brain that causes unilateral hemispheric atrophy, neurological dysfunction and refractory epilepsy. Hemispherotomy is considered the most effective treatment today, but some cases present certain peculiarities that can seriously affect the decision to go ahead with this procedure. To evaluate the post-operative progress made by children with RE who have undergone hemispherotomy surgery, and who, in the pre-operative assessment, presented certain characteristics that complicated the decision to perform surgery. The sample selected for study consisted of the cases of RE attended in the Hospital Sao Paulo between 2003 and 2012 who, in the pre-surgery evaluation, presented clinical, electroencephalographic or neuroimaging evidence of involvement of both brain hemispheres, compromise of the dominant brain hemisphere, absence of severe neurological deficit and absence of criteria for refractory epilepsy and atypical crises. The post-operative assessment of the epileptic seizures was evaluated using the Engel scale; motor function was analysed with the Gross Motor Function Classification System and Manual Ability Classification System scales, and language was evaluated clinically. Six cases were selected (four girls), with a mean age at clinical onset of 3.3 ± 1.2 years (range: 2-7 years) and a mean age at hemispherotomy of 6.7 years (range: 2.3-16.5 years). The mean post-surgery follow-up time was three years (range: 0.5-7.2 years). In the post-surgery evaluation of the epileptic seizures, four cases were classified as Engel class I (66%); there was some improvement in motor functioning in five of them, and language improved in all cases. Hemispherotomy must be considered an efficient option for treatment in children with RE.
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DEFF Research Database (Denmark)
Villafafila, Ada; Thomsen, Kaj; Stenby, Erling Halfdan
2006-01-01
Two additional parameters to account for the pressure dependency of solubility are added to the Extended UNIQUAC model presented by Thomsen and Rasmussen (1999). The improved model has been used for correlation and prediction of vapor-liquid-solid equilibrium for different carbonate systems (CaCO...
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Morphing patient-specific musculoskeletal models
DEFF Research Database (Denmark)
Rasmussen, John; Galibarov, Pavel E.; Al-Munajjed, Amir
the resulting models do indeed represent the patients’ biomechanics. As a particularly challenging case, foot deformities based only on point sets recovered from surface scans are considered as shown in the figure. The preliminary results are promising for the cases of severe flat foot and metatarsalgia while...... other conditions may require CT or MRI data. The method and its theoretical assumptions, advantages and limitations are presented, and several examples will illustrate morphing to patient-specific models. [1] Carbes S; Tørholm S; Rasmussen, J. A Detailed Twenty-six Segments Kinematic Foot model...
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Li, Jing; Chen, Chang Xun; Shen, Yun Hui
2011-05-17
Total glucosides of paeony (TGP), compounds extracted from the roots of Paeonia lactiflora Pall, have been used as an anti-inflammatory drug for the treatment of rheumatoid arthritis (RA) in China. Inflammation plays a critical role in the development of atherosclerotic vascular disease. Risk of cardiovascular diseases is significantly higher in patients with RA than in normal population. It has a great significance to study the effects of TGP on atherosclerosis. To investigate the effects of TGP on atherosclerosis induced by excessive administration of vitamin D and cholesterol in rats and study the mechanisms involved. Atherosclerosis was induced by excessive administration of vitamin D and cholesterol in rats. TGP was intragastrically administered for 15 weeks. The serum concentrations of total cholesterol (TC), triglyceride (TG), low density lipoprotein-cholesterol (LDL-C) and high density lipoprotein-cholesterol (HDL-C) were measured by automatic biochemistry analyzer. Apolipoprotein A1 (ApoA1) and apolipoprotein B (ApoB) were determined by immunoturbidimetry method, tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6) and C-reactive protein (CRP) were measured by enzyme-linked immunosorbent assay (ELISA) method. The morphological changes of aorta were observed with optical microscopy. Compared to controls, TGP significantly lowered the serum level of TC, TG, LDL-C, ApoB, TNF-alpha, IL-6 and CRP, increased the ratios of HDL-C/LDL-C and ApoA1/ApoB, decreased the intima-media thickness (IMT) of abdominal aortal wall and improved the morphological change of the aorta. TGP may attenuate the development of atherosclerotic disease. The beneficial effects are associated with its lowering blood lipids and inhibiting the expression of inflammatory cytokines. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.
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Directory of Open Access Journals (Sweden)
Daqiu Zhao
2015-09-01
Full Text Available Herbaceous peony (Paeonia lactiflora Pall., one of the world’s most important ornamental plants, is highly susceptible to Botrytis cinerea, and improving resistance to this pathogenic fungus is a problem yet to be solved. MicroRNAs (miRNAs play an essential role in resistance to B. cinerea, but until now, no studies have been reported concerning miRNAs induction in P. lactiflora. Here, we constructed and sequenced two small RNA (sRNA libraries from two B. cinerea-infected P. lactiflora cultivars (“Zifengyu” and “Dafugui” with significantly different levels of resistance to B. cinerea, using the Illumina HiSeq 2000 platform. From the raw reads generated, 4,592,881 and 5,809,796 sRNAs were obtained, and 280 and 306 miRNAs were identified from “Zifengyu” and “Dafugui”, respectively. A total of 237 conserved and 7 novel sequences of miRNAs were differentially expressed between the two cultivars, and we predicted and annotated their potential target genes. Subsequently, 7 differentially expressed candidate miRNAs were screened according to their target genes annotated in KEGG pathways, and the expression patterns of miRNAs and corresponding target genes were elucidated. We found that miR5254, miR165a-3p, miR3897-3p and miR6450a might be involved in the P. lactiflora response to B. cinerea infection. These results provide insight into the molecular mechanisms responsible for resistance to B. cinerea in P. lactiflora.
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Model-Based Integration and Interpretation of Data
DEFF Research Database (Denmark)
Petersen, Johannes
2004-01-01
Data integration and interpretation plays a crucial role in supervisory control. The paper defines a set of generic inference steps for the data integration and interpretation process based on a three-layer model of system representations. The three-layer model is used to clarify the combination...... of constraint and object-centered representations of the work domain throwing new light on the basic principles underlying the data integration and interpretation process of Rasmussen's abstraction hierarchy as well as other model-based approaches combining constraint and object-centered representations. Based...
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Directory of Open Access Journals (Sweden)
Ma X
2015-09-01
Full Text Available Xiao Ma,1,2 Yan-ling Zhao,2 Yun Zhu,3 Zhe Chen,1,2 Jia-bo Wang,4 Rui-yu Li,1,4 Chang Chen,1,2 Shi-zhang Wei,1,2 Jian-yu Li,3 Bing Liu,5 Rui-lin Wang,3 Yong-gang Li,3 Li-fu Wang,3 Xiao-he Xiao4 1Pharmacy College, Chengdu University of Traditional Chinese Medicine, Chengdu, People’s Republic of China; 2Department of Pharmacy, 302 Military Hospital of People’s Liberation Army, Beijing, People’s Republic of China; 3Department of Integrative Medical Center, 302 Military Hospital of People’s Liberation Army, Beijing, People’s Republic of China; 4China Military Institute of Chinese Medicine, 302 Military Hospital of People’s Liberation Army, Beijing, People’s Republic of China; 5School of Chinese Medicine, The University of Hong Kong, Hong Kong Background: Paeonia lactiflora Pall. (PLP, a traditional Chinese herbal medicine, has been used for hepatic disease treatment over thousands of years. In our previous study, PLP was shown to demonstrate therapeutic effect on hepatitis with severe cholestasis. The aim of this study was to evaluate the antioxidative effect of PLP on alpha-naphthylisothiocyanate (ANIT-induced cholestasis by activating NF-E2-related factor 2 (Nrf2 via phosphatidylinositol 3-kinase (PI3K/Akt signaling pathway. Materials and methods: Liquid chromatography-mass spectrometry (LC-MS was performed to identify the main compounds present in PLP. The mechanism of action of PLP and its therapeutic effect on cholestasis, induced by ANIT, were further investigated. Serum indices such as total bilirubin (TBIL, direct bilirubin (DBIL, aspartate aminotransferase (AST, alanine aminotransferase (ALT, alkaline phosphatase (ALP, γ-glutamyl transpeptidase (γ-GT, and total bile acid (TBA were measured, and histopathology of liver was also performed to determine the efficacy of treatment with PLP. Moreover, in order to illustrate the underlying signaling pathway, liver glutathione (GSH content and mRNA or protein levels of glutamate
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Goode, N; Salmon, P M; Taylor, N Z; Lenné, M G; Finch, C F
2017-10-01
One factor potentially limiting the uptake of Rasmussen's (1997) Accimap method by practitioners is the lack of a contributing factor classification scheme to guide accident analyses. This article evaluates the intra- and inter-rater reliability and criterion-referenced validity of a classification scheme developed to support the use of Accimap by led outdoor activity (LOA) practitioners. The classification scheme has two levels: the system level describes the actors, artefacts and activity context in terms of 14 codes; the descriptor level breaks the system level codes down into 107 specific contributing factors. The study involved 11 LOA practitioners using the scheme on two separate occasions to code a pre-determined list of contributing factors identified from four incident reports. Criterion-referenced validity was assessed by comparing the codes selected by LOA practitioners to those selected by the method creators. Mean intra-rater reliability scores at the system (M = 83.6%) and descriptor (M = 74%) levels were acceptable. Mean inter-rater reliability scores were not consistently acceptable for both coding attempts at the system level (M T1 = 68.8%; M T2 = 73.9%), and were poor at the descriptor level (M T1 = 58.5%; M T2 = 64.1%). Mean criterion referenced validity scores at the system level were acceptable (M T1 = 73.9%; M T2 = 75.3%). However, they were not consistently acceptable at the descriptor level (M T1 = 67.6%; M T2 = 70.8%). Overall, the results indicate that the classification scheme does not currently satisfy reliability and validity requirements, and that further work is required. The implications for the design and development of contributing factors classification schemes are discussed. Copyright © 2017 Elsevier Ltd. All rights reserved.
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[Rasmussen encephalitis and non-herpetic acute limbic encephalitis].
Takahashi, Yukitoshi; Kubota, Yuko; Yamasaki, Etsuko; Matsuda, Kazumi
2008-03-01
Rasmussen syndrome (RS) and non-herpetic acute limbic encephalitis (NHALE) have pathophysiological background related with autoimmunity to glutamate receptors (GluRs) after infections. RS and NHALE were reviewed, depending mainly on our recent studies. RS is the prototype of autoimmune-mediated epilepsy. In patients with RS, several kinds of autoantibodies against neuronal molecules, for example, GluR3, GluRepsilon2 (NMDA-R2B), etc., are reported. These autoantibodies are not specific for RS. About autoantibodies against GluR3, significance and stimulating effects to GluR3 are controversial. Autoantibodies against GluRepsilon2 were detected in all patients within six months from epilepsy onset, and in some patients at chronic stage. These data suggest that autoantibodies against GluRepsilon2 may be involved in the pathological mechanisms in the early stage, but we could not confirm the effect of the autoantibodies from RS patients on excitatory postsynaptic NMDA current using patch clump methods. However, anti-double-stranded DNA antibodies in patients with SLE are reported to cross-react with n-terminal of GluRepsilon2, and cause neuronal apoptosis in rat hippocampus, ensuing memory impairment, and emotional behavior impairment in mice. Therefore, autoantibodies against GluRepsilon2 may contribute to the cognitive and behavioral changes in RS. Concerning about cellular immunity in RS, lymphocytes stimulating tests revealed peripheral lymphocytes sensitized by antigens containing GluRepsilon2. Cytotoxic T cells (CTLs) excreting Granzyme B were reported in resected brain tissue, and we confirmed the elevated levels of Granzyme B, not in sera, but in CSF. These data suggest that CTLs activated by infection invade into CNS, and recognize neural antigens, and excrete Granzyme B. The incidence of NHALE is 4.1/1 million/year in Japanese adults. Our study in 91 adult patients with NHALE revealed the following characteristics. Mean onset age was 35.2 +/- 16.9 years old
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Dual pathology in Rasmussen's encephalitis: a study of seven cases and review of the literature.
Takei, Hidehiro; Wilfong, Angus; Malphrus, Amy; Yoshor, Daniel; Hunter, Jill V; Armstrong, Dawna L; Bhattacharjee, Meenakshi B
2010-08-01
Dual pathology has previously been reported in less than 10% of cases of Rasmussen's encephalitis (RE). Given the rarity of RE, it appears unlikely that dual pathology in RE is merely a coincidence. We therefore reviewed all cases of RE experienced in our institution to assess for an additional/associated pathology. A total of seven patients with RE were identified in our archives. Seven children (4 boys and 3 girls, age range: 3-16 years, mean: 9.5 years) with medically refractory epilepsy underwent surgical resection for intractable seizures. The surgical specimens were examined with routine neurohistological techniques, and immunohistochemistry was performed with an extensive panel of antibodies for viruses, lymphocytes, microglia/macrophages, human leukocyte antigen (HLA)-DR, astrocytes, and neurons. Relevant literature was reviewed. Microscopically, all seven cases demonstrated the inflammatory pathology of RE in the cortex and white matter with leptomeningeal and perivascular lymphocytic infiltration, microglial nodules with/without neuronophagia, neuronal loss and gliosis. The HLA-DR antibody was extremely helpful in highlighting the extent of microglial cell proliferation/activation that was not appreciable with standard histology. An unexpected finding in all seven cases was the presence of cortical dysplasia. In our series of seven cases, there was co-occurrence of the inflammatory/destructive pathology of RE with malformative/dysplastic features in cortical architecture in 100% of cases, raising questions about the possible relationships between the two entities. Awareness of the possibility of dual pathology in RE is important for clinical and pathological diagnosis, and may affect the management and outcome of these patients. Immunohistochemistry is very helpful to make a definitive diagnosis of both pathologies.
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DEFF Research Database (Denmark)
Garcia, Ada V.; Thomsen, Kaj; Stenby, Erling Halfdan
2005-01-01
Pressure parameters are added to the Extended UNIQUAC model presented by Thomsen and Rasmussen (1999). The improved model has been used for correlation and prediction of solid-liquid equilibrium (SLE) of scaling minerals (CaSO4, CaSO4·2H2O, BaSO4 and SrSO4) at temperatures up to 300°C and pressur...
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DEFF Research Database (Denmark)
Christiansen, Ask Vest; Gleaves, John
2014-01-01
Compared to football-players cyclists are virtuous role models. Yes, Lance Armstrong, Michael Rasmussen and other riders have doped, and because of this they have received the predicate as the most immoral athletes in the sporting world. But if morality is not only a question of whether a person ...... has enhanced his or hers performances by the use of various drugs (and lied about it), but also is about human beings’ relations and interactions, then cycling isn’t as depraved as we like to tell each other. Football is much worse....
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Directory of Open Access Journals (Sweden)
Subramanyam K.S.V.
2015-09-01
Full Text Available Prakasam Igneous Province (PIP is an important geological domain in the Eastern Dharwar Craton (EDC, found in the junction zone between the EDC and Eastern Ghat Mobile Belt (EGMB. The Pedda Cherlo Palle (PCP gabbros are massive, leucocratic-mesocractic, and show cumulus textures with minerals plagioclase, cpx, and amphiboles. Compositionally, plagioclase is a labradorite-bytownite, cpx is diopside to augite, olivines are hyalosiderites and amphiboles are magnesiohornblendes. PCP gabbros have normal SiO2, high Al2O3, moderate to high TiO2, Na2O and medium Fe2O3, so, classified as subalkaline tholeiitic gabbros. Fractionated rare earth element (REE patterns, high abundance of large ion lithofile elements (LILE and transitional metals coupled with light REE (LREE relative enrichment over heavy REE (HREE and Nb are characteristics of partial melting of depleted mantle and melts that have undergone fractional crystalisation. These partial melts are enriched in LREE and LILE, due to the addition of slab derived sediment and fluids. PCP gabbros contain low abundance (5.1 to 24.6 ng/g of platinum group elements (PGE, and show an increase in the order Ir>Os>Pt>Ru»Pd>Rh. We propose that the subduction related intraoceanic island arc might have accreted to the southeastern margin of India to the east of Cuddapah basin in a collisional regime that took place during Ur to Rodinia amalgamations.
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Energy Technology Data Exchange (ETDEWEB)
Lee, Jung Woon; Park, Young Tack [Soongsil University, Seoul (Korea, Republic of)
1996-07-01
The main objective of this project is modeling of human operator in a main control room of Nuclear Power Plant. For this purpose, we carried out research on knowledge representation and inference method based on Rasmussen`s decision ladder structure. And we have developed SACOM(Simulation= Analyzer with a Cognitive Operator Model) using G2 shell on Sun workstations. SACOM consists of Operator Model, Interaction Analyzer, Situation Generator. Cognitive model aims to build a more detailed model of human operators in an effective way. SACOM is designed to model knowledge-based behavior of human operators more easily. The followings are main research topics carried out this year. First, in order to model knowledge-based behavior of human operators, more detailed scenarios are constructed. And, knowledge representation and inference methods are developed to support the scenarios. Second, meta knowledge structures are studied to support human operators 4 types of diagnoses. This work includes a study on meta and scheduler knowledge structures for generate-and-test, topographic, decision tree and case-based approaches. Third, domain knowledge structure are improved to support meta knowledge. Especially, domain knowledge structures are developed to model topographic diagnosis model. Fourth, more applicable interaction analyzer and situation generator are designed and implemented. The new version is implemented in G2 on Sun workstations. 35 refs., 49 figs. (author)
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A geometric model for Hochschild homology of Soergel bimodules
DEFF Research Database (Denmark)
Webster, Ben; Williamson, Geordie
2008-01-01
An important step in the calculation of the triply graded link homology of Khovanov and Rozansky is the determination of the Hochschild homology of Soergel bimodules for SL(n). We present a geometric model for this Hochschild homology for any simple group G, as B–equivariant intersection cohomology...... on generators whose degree is explicitly determined by the geometry of the orbit closure, and to describe its Hilbert series, proving a conjecture of Jacob Rasmussen....
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Directory of Open Access Journals (Sweden)
Saijie Gong
Full Text Available Herbaceous peony (Paeonia lactiflora Pall. is a well-known traditional flower in China and is widely used for landscaping and garden greening due to its high ornamental value. However, disease spots usually appear after the flowering of the plant and may result in the withering of the plant in severe cases. This study examined the disease incidence in an herbaceous peony field in the Yangzhou region, Jiangsu Province. Based on morphological characteristics and molecular data, the disease in this area was identified as a gray mold caused by Botrytis cinerea. Based on previously obtained transcriptome data, eight libraries generated from two herbaceous peony cultivars 'Zifengyu' and 'Dafugui' with different susceptibilities to the disease were then analyzed using digital gene expression profiling (DGE. Thousands of differentially expressed genes (DEGs were screened by comparing the eight samples, and these genes were annotated using the Gene ontology (GO and Kyoto encyclopedia of genes and genomes (KEGG database. The pathways related to plant-pathogen interaction, secondary metabolism synthesis and antioxidant system were concentrated, and 51, 76, and 13 disease resistance-relevant candidate genes were identified, respectively. The expression patterns of these candidate genes differed between the two cultivars: their expression of the disease-resistant cultivar 'Zifengyu' sharply increased during the early stages of infection, while it was relatively subdued in the disease-sensitive cultivar 'Dafugui'. A selection of ten candidate genes was evaluated by quantitative real-time PCR (qRT-PCR to validate the DGE data. These results revealed the transcriptional changes that took place during the interaction of herbaceous peony with B. cinerea, providing insight into the molecular mechanisms of host resistance to gray mold.
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A situation-response model for intelligent pilot aiding
Schudy, Robert; Corker, Kevin
1987-01-01
An intelligent pilot aiding system needs models of the pilot information processing to provide the computational basis for successful cooperation between the pilot and the aiding system. By combining artificial intelligence concepts with the human information processing model of Rasmussen, an abstraction hierarchy of states of knowledge, processing functions, and shortcuts are developed, which is useful for characterizing the information processing both of the pilot and of the aiding system. This approach is used in the conceptual design of a real time intelligent aiding system for flight crews of transport aircraft. One promising result was the tentative identification of a particular class of information processing shortcuts, from situation characterizations to appropriate responses, as the most important reliable pathway for dealing with complex time critical situations.
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Hydraulic Evaluation of the LEANCON Wave Energy Converter
DEFF Research Database (Denmark)
Kofoed, Jens Peter; Frigaard, Peter
This report is a product of the co-operation agreement between Aalborg University and LEANCON (by Kurt Due Rasmussen) on the evaluation and development of the LEANCON wave energy converter (WEC). The work reported here has focused on evaluation of the power production of the device, based...... on laboratory testing of a model of the WEC provided by LEANCON. LEANCON, represented by Kurt Due Rasmussen, has been heavily involved in the testing of the device, including the instrumentation, model setup and execution of the tests in the laboratory, all under the supervision of the personnel of the Wave...... Energy Research Group at Department of Civil Engineering, Aalborg University....
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Directory of Open Access Journals (Sweden)
Xiao eMa
2016-02-01
Full Text Available Background: The dried root of Paeonia lactiflora Pall. (PLP is a classical Chinese herbal medicine that has been used to treat hepatic disease for thousands of years. Our previous work suggested that PLP can be used to treat hepatitis with severe cholestasis. This study explored the mechanism by which PLP affects ANIT-induced cholestasis in rats using a metabolomics approach.Methods: The effects of PLP on serum indices (TBIL, DBIL, AST, ALT, ALP and TBA and the histopathology of the liver were analyzed. Moreover, UHPLC-Q-TOF was performed to identify the possible effect of PLP on metabolites. The pathway analysis was conducted to illustrate the pathways and network by which PLP treats cholestasis. Result: High-dose PLP remarkably down-regulated the serum indices and alleviated histological damage to the liver. Metabolomics analyses showed that the therapeutic effect of high-dose PLP is mainly associated with the regulation of several metabolites, such as glycocholic acid, taurocholic acid, glycochenodeoxycholic acid, L(D-arginine and L-tryptophan. A pathway analysis showed that the metabolites were related to bile acid secretion and amino acid metabolism. In addition, the significant changes in bile acid transporters also indicated that bile acid metabolism might be involved in the therapeutic effect of PLP on cholestasis. Moreover, a principal component analysis indicated that the metabolites in the high-dose PLP group were closer to those of the control, whereas those of the moderate dose or low-dose PLP group were closer to those of the ANIT group. This finding indicated that metabolites may be responsible for the differences between the effects of low-dose and moderate-dose PLP. Conclusions: The therapeutic effect of high-dose PLP on cholestasis is possibly related to regulation of bile acid secretion and amino acid metabolism. Moreover, these findings may help better understand the mechanisms of disease and provide a potential therapy for
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... cognitive deficits, and problems with speech. In some cases, the disease can progress to involve the opposite brain hemisphere. Clinical Trials Throughout the U.S. and Worldwide NINDS Clinical ... Definition Rasmussen’s encephalitis is a rare, chronic inflammatory neurological ...
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International Nuclear Information System (INIS)
Suh, Sang Moon; Cheon, Se Woo; Lee, Yong Hee; Lee, Jung Woon; Park, Young Taek
1996-01-01
SACOM(Simulation Analyser with Cognitive Operator Model) is being developed at Korea Atomic Energy Research Institute to simulate human operator's cognitive characteristics during the emergency situations of nuclear power plans. An operator model with error mechanisms has been developed and combined into SACOM to simulate human operator's cognitive information process based on the Rasmussen's decision ladder model. The operational logic for five different cognitive activities (Agents), operator's attentional control (Controller), short-term memory (Blackboard), and long-term memory (Knowledge Base) have been developed and implemented on blackboard architecture. A trial simulation with a scenario for emergency operation has been performed to verify the operational logic. It was found that the operator model with error mechanisms is suitable for the simulation of operator's cognitive behavior in emergency situation
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African Journal of Biotechnology - Vol 12, No 31 (2013)
African Journals Online (AJOL)
induced fatty liver model of consecutive extracts from Rosa davurica Pall · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Ying Wei, Muyi Cai, Ruizeng Gu, Jun Lu, Feng Lin, Baoping Ji ...
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Can Household Benefit from Stochastic Programming Models?
DEFF Research Database (Denmark)
Rasmussen, Kourosh Marjani; Madsen, Claus A.; Poulsen, Rolf
2014-01-01
The Danish mortgage market is large and sophisticated. However, most Danish mortgage banks advise private home-owners based on simple, if sensible, rules of thumb. In recent years a number of papers (from Nielsen and Poulsen in J Econ Dyn Control 28:1267–1289, 2004 over Rasmussen and Zenios in J...... Risk 10:1–18, 2007 to Pedersen et al. in Ann Oper Res, 2013) have suggested a model-based, stochastic programming approach to mortgage choice. This paper gives an empirical comparison of performance over the period 2000–2010 of the rules of thumb to the model-based strategies. While the rules of thumb.......3–0.9 %-points (depending on the borrower’s level of conservatism) compared to the rules of thumb without increasing the risk. The answer to the question in the title is thus affirmative....
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Rumsansning mellem vane og oplevelse
DEFF Research Database (Denmark)
Reeh, Henrik
2004-01-01
Walter Benjamin, Steen Eiler Rasmussen, arkitektur, sansning, vane, taktilitet, oplevelse, erfaring, Rom......Walter Benjamin, Steen Eiler Rasmussen, arkitektur, sansning, vane, taktilitet, oplevelse, erfaring, Rom...
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Elasto-plastic hardening models adjustment to ferritic, austenitic and austenoferritic Rebar
International Nuclear Information System (INIS)
Hortigóna, B.; Gallardo, J.M.; Nieto-García, E.J.; López, J.A.
2017-01-01
The elastoplastic behaviour of steel used for structural member fabrication has received attention to facilitate a mechanical-resistant design. New Zealand and South African standards have adopted various theoretical approaches to describe such behaviour in stainless steels. With respect to the building industry, describing the tensile behaviour of steel rebar used to produce reinforced concrete structures is of interest. Differences compared with the homogenous material described in the above mentioned standards and related literatures are discussed in this paper. Specifically, the presence of ribs and the TEMPCORE® technology used to produce carbon steel rebar may alter the elastoplastic model. Carbon steel rebar is shown to fit a Hollomon model giving hardening exponent values on the order of 0.17. Austenitic stainless steel rebar behaviour is better described using a modified Rasmussen model with a free fitted exponent of 6. Duplex stainless steel shows a poor fit to any previous model. [es
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DEFF Research Database (Denmark)
Thoft-Christensen, Palle
The chapters in this Volume 7 of a series of PAPERS are based on papers published in the period 2004 - 2008 authored/co-authored by Palle Thoft-Christensen......The chapters in this Volume 7 of a series of PAPERS are based on papers published in the period 2004 - 2008 authored/co-authored by Palle Thoft-Christensen...
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Tebbens, L.A.
1999-01-01
<p>All fluvial systems ultimately drain into alluvial basins, where the weathering products of their upstream drainage areas accumulate over a time-span varying from 10 0to 10 6years. Most silted-up alluvial basins are low-gradient deltas that are
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En fascinerende fortælling om det 20. århundredes musik
DEFF Research Database (Denmark)
Bonde, Lars Ole
2011-01-01
Anmeldelse af Karl Aage Rasmussen: Musik i det tyvende århundrede: En fortælling. Gyldendal 2011.......Anmeldelse af Karl Aage Rasmussen: Musik i det tyvende århundrede: En fortælling. Gyldendal 2011....
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Muslim Women's Civil Society Groups in Nigeria, Ghana and Tanzania
African Journals Online (AJOL)
neoliberal development models arguing that the WB, IMF, USAID and others have .... Rasmussen, and Pooja Rishi (2010) disrupt narratives of microcredit that ... in using the market dismantle the nuclear depiction of kinship networks. ..... asserting inclusive models of development could benefit the BRICS new development.
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Visual behaviour analysis and driver cognitive model
Energy Technology Data Exchange (ETDEWEB)
Baujon, J.; Basset, M.; Gissinger, G.L. [Mulhouse Univ., (France). MIPS/MIAM Lab.
2001-07-01
Recent studies on driver behaviour have shown that perception - mainly visual but also proprioceptive perception - plays a key role in the ''driver-vehicle-road'' system and so considerably affects the driver's decision making. Within the framework of the behaviour analysis and studies low-cost system (BASIL), this paper presents a correlative, qualitative and quantitative study, comparing the information given by visual perception and by the trajectory followed. This information will help to obtain a cognitive model of the Rasmussen type according to different driver classes. Many experiments in real driving situations have been carried out for different driver classes and for a given trajectory profile, using a test vehicle and innovative, specially designed, real-time tools, such as the vision system or the positioning module. (orig.)
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DEFF Research Database (Denmark)
Heede, Dag
2017-01-01
An exploration of the Antinous myth in early modern Danish homosexual literature and drama around 1800, including interpretations of two forgotten dramas: "Hadrian" by Konrad Simonsen and "Antinous" by Palle Rosenkrantz.......An exploration of the Antinous myth in early modern Danish homosexual literature and drama around 1800, including interpretations of two forgotten dramas: "Hadrian" by Konrad Simonsen and "Antinous" by Palle Rosenkrantz....
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DEFF Research Database (Denmark)
Juul, Rasmus Vestergaard; Rasmussen, Sten; Kreilgaard, Mads
at Orthopaedic Department, Aalborg University Hospital, Denmark during the period May-Dec 2012. Morphine administration times (estimated precision: ±5mins), formulations and doses were extracted from medical journals in the hospitalization period or until 96 hours after surgery. RTTE modelling was performed......Title: How Repeated Time To Event (RTTE) modelling of opioid requests after surgery may improve future post-operative pain management Author: Rasmus Vestergaard Juul (1) Sten Rasmussen (2) Mads Kreilgaard (1) Ulrika S. H. Simonsson (3) Lona Louring Christrup (1) Trine Meldgaard Lund (1) Institution...... of surgery specific, drug concentration related, population specific and/or time-varying covariates of opioid requests and pain events. Conclusions: A framework has been developed based on RTTE modelling that may help improve future pain management by 1) Identification of surgery specific patterns in pain...
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VK-æraens departementschefer - troldmændene fra Oz
DEFF Research Database (Denmark)
Nielsen, Peter Heyn
2014-01-01
37 personer nåede at være departementschefer i perioden fra 2001 til 2011 under henholdsvis statsminister Anders Fogh Rasmussen og statsminister Lars Løkke Rasmussen. Nogle var i perioden departementschefer i flere forskellige ministerier, således at man fandt 48 forskellige departements-chefs¬sti...
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International Nuclear Information System (INIS)
Santina, M.D.
1978-01-01
The safety distance for Angra dos Reis Nuclear Power Plant are calculated, based on the model of the maximum credible accident for PWR power reactors and on the calculation of the dose due to hypothetical accidental release of radioactivity, using the model of radiation dispersion in the atmosphere. The safety distances for the Angra dos Reis reactors are also calculated using the model of the nine accident categories of the Rasmussen Report. The values of probability associated to each type of accident are used with the respective fractions of radiation release to the atmosphere. The soil contamination is also calculated for all the accidents considered and for several conditions of atmospheric stability, according to the model developed by Chamberlain. The program ACRA-II is used for calculation of the diffusion of radiation in the atmosphere, and the doses associated to it [pt
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Prophylactic Fasciotomy in a Porcine Model of Extremity Trauma
2014-07-16
Morrison, MRCS,b,c,d Jerry R. Spencer, BS,a James D. Ross, PhD,a and Todd E. Rasmussen, MD, FACSa,e,f,* a59th Medical Wing, Joint Base San Antonio, San...Vascular injury Extremity Ischemiaereperfusion Recovery Neuromuscular Functional Fasciotomy a b s t r a c t Background: Extremity injury, with...prophylactic fasciotomy on neuromuscular recovery, labora- tory markers of ischemiaereperfusion, and tissue injury as determined by histologic evaluation. We
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Is an Inuit Literary History Possible?
Martin, Keavy
2010-01-01
In 1921, the Greenlandic anthropologist Knud Rasmussen set out to travel twenty thousand miles by dog team across Inuit Nunaat--the Inuit homeland. During this three-year journey--the famous Fifth Thule Expedition--Rasmussen was struck by the similarities in the language and culture of Inuit communities across the entire Arctic. Considering the…
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Critical Exchange: Peculiar Bedfellows--Gender, Sexuality, Religion and Schooling: A Reply to Stern
Rasmussen, Mary L.
2017-01-01
Mary L. Rasmussen is a sociologist of education with expertise in studies of gender and sexuality. This angle of scrutiny (Harwood 2006) is her point of departure in conversations about schooling and religion. From this angle, Rasmussen believes that schooling and religion can be incredibly powerful in creating community. She is also clear that…
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Stemcell Information: SKIP000748 [SKIP Stemcell Database[Archive
Lifescience Database Archive (English)
Full Text Available B1345. Ph1 chromosome-positive human acute lymphoblastic leukemia cell line. Single Ph1 chromosome observed. 白血病... SKIP000748 ... acute lymphoblastic leukemia cell line 急性リンパ芽球 ... Diseased PALL-2 PALL...c and molecular analysis of Ph1-chromosome-positive acute lymphoblastic leukemia cell lines. Miyagi T, Ohyas...-2 JCRB1345 JCRB1345 急性リンパ性白血病 C910 Acute lymphoblastic leukaemia [ALL] 613065 ... -- Male ... Yes No JCR
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Abad-Vivero, Erika N; Thrasher, James F; Arillo-Santillán, Edna; Pérez-Hernández, Rosaura; Barrientos-Gutíerrez, Inti; Kollath-Cattano, Christy; Mejía, Raúl; Sargent, James D
2016-12-01
Use of flavour capsule varieties (FCVs) of cigarettes has rapidly increased in many countries. Adolescents are attracted to flavours; yet, surprisingly, no quantitative study has explored adolescents' perceptions of these products. To characterise the appeal of FCVs for young adolescents in Mexico. In 2015, surveys were conducted with a representative sample of Mexican middle school students (n=10 124; ages 11-16 years; mean 12.4 years). Students viewed and rated packs for FCVs and non-FCVs from major brands (Marlboro, Camel, Pall Mall), with brand names removed. For each pack, students were asked to write the brand name (ie, brand recall), to evaluate pack attractiveness, and to indicate the pack they were most interested in trying (including a 'none' option). Logistic generalised estimating equation (GEE) models regressed brand recall, pack attractiveness and interest in trying on brand and FCV (yes vs no), controlling for sociodemographics and smoking risk factors. Marlboro regular, Camel regular, Camel light and Pall Mall FCVs were most often recalled (25%, 17%, 9%, 8%). Packs for Pall Mall FCVs and Camel FCVs were most often rated as very attractive (13%, 9%, respectively) and of interest for trial (22%, 13%) along with Marlboro regular (14%). In GEE models, FCVs were independently associated with greater attractiveness (adjusted OR (AOR)=1.83, 95% CI 1.72 to 1.94) and interest in trying (AOR=1.74, 95% CI 1.54 to 1.96). Perceived pack attractiveness was also independently associated with greater interest in trying (AOR=5.63, 95% CI 4.74 to 6.68). FCVs appear to be generating even greater appeal among young adolescents than established non-FCVs in dominant brand families. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.
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DEFF Research Database (Denmark)
Huang, Qian; Rasmussen, Henrik K.
2017-01-01
, proposed by Rasmussen and Huang (Rheol Acta 53(3):199–208 (2014a)), predicts the extensional viscosity well for the dilutions with lower concentrations. However, for the 70 and 90% 545 kg/mole samples which represent the transition between the diluted and undiluted states, the model predictions are less...
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MP.EXE Microphone pressure sensitivity calibration calculation program
DEFF Research Database (Denmark)
Rasmussen, Knud
1999-01-01
MP.EXE is a program which calculates the pressure sensitivity of LS1 microphones as defined in IEC 61094-1, based on measurement results performed as laid down in IEC 61094-2.A very early program was developed and written by K. Rasmussen. The code of the present heavily extended version is writte...... by E.S. Olsen.The present manual is written by K.Rasmussen and E.S. Olsen....
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Directory of Open Access Journals (Sweden)
Vilches de Frutos, M. Francisca
2002-06-01
Full Text Available Current research on twentieth-century Spanish theater reveals a high number of historical plays, a tendency that has continued during the last five years. Some of the most significant writers currently writing for the stage are actively revising the recent past in their work. In this context, three playwrights stand out —Jose Ramon Fernandez, Yolanda Pallin and Javier G. Yague— thanks to the critical and commercial success of their Las manos (Hands, a play about young people who live in a rural area of Spain during the decade of the 1960s. The study of the play's themes and its reception bring to light the reasons behind this historical recreation and the favorable response accorded it by critics and audiences.El análisis de las representaciones escénicas llevadas a cabo en España durante el siglo XX permite apreciar la existencia de un elevado número de obras históricas. Esta tendencia ha tenido continuidad en el último lustro, donde algunos de los más destacados autores dramáticos no han dudado en iniciar una revisión del pasado reciente. En este contexto no debe sorprender el éxito crítico y comercial alcanzado por José Ramón Fernández, Yolanda Pallín y Javier G. Yagüe con Las manos, una obra protagonizada por jóvenes pertenecientes al ámbito rural español en la década de los sesenta. El estudio de sus claves temáticas y de su recepción permitirá explicar las razones para recrear este período histórico y las causas de su excelente acogida.
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DEFF Research Database (Denmark)
Barsberg, Søren Talbro; Lee, Y.-I.; Rasmussen, Hanne Nina
2018-01-01
Cite this article: Barsberg ST, Lee Y-I, Rasmussen HN. Development of C-lignin with G/S-lignin and lipids in orchid seed coats – an unexpected diversity exposed by ATR-FT-IR spectroscopy. Seed Science Research https:// doi.org/10.1017/S0960258517000344......Cite this article: Barsberg ST, Lee Y-I, Rasmussen HN. Development of C-lignin with G/S-lignin and lipids in orchid seed coats – an unexpected diversity exposed by ATR-FT-IR spectroscopy. Seed Science Research https:// doi.org/10.1017/S0960258517000344...
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Palle Qvist's Blog about Digital Teaching
DEFF Research Database (Denmark)
Qvist, Palle
2010-01-01
Blog created to support the first pedagogical day about e-learning arranged by the official AAU – “Pedagogical open day in Aalborg 17th of March 2010″. New articles added continuosly......Blog created to support the first pedagogical day about e-learning arranged by the official AAU – “Pedagogical open day in Aalborg 17th of March 2010″. New articles added continuosly...
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Uikala prügila sai puhastusseadmed / Külli Kriis
Kriis, Külli, 1961-
2004-01-01
Ilmunud ka: Severnoje Poberezhje, 22. mai 2004, lk. 3. 21. mail 2004 Ida-Virumaal Uikala prügilas avatud puhastusseadmete kompleksist, mille valmistas ja paigaldas rahvusvaheline ettevõte Pall Corporation
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THE ROLE OF POLYPLOIDY IN ADAPTATION AND SETTLING OF STEPPE SHRUBS IN CENTRAL ASIA
Directory of Open Access Journals (Sweden)
Natalia V Ekimova
2011-03-01
Full Text Available Chromosome numbers for some species of Central Asia steppe shrubs are given: Rhamnus erythroxylon Pall. (Rhamnaceae, Caragana buriatica Peschk. (Fabaceae, Amygdalus pedunculata Pall., Armeniaca sibirica (L. Lam. (Rosaceae, Atraphaxis pungens (Bieb. Jaub. et Spach. and A. frutescens (L. C. Koch (Polygonaceae. Chromosome numbers of some species were determined for the first time. Comparative analysis of adaptive properties of polyploid and diploid species has been conducted. It was established that natural polyploids are more adaptive to existence in extreme conditions. They possess by high potential for survival and characterized by more high level of intraspecific polymorphism, abundant flowering and fruitification, ability of propagate both generative and vegetative means, high seed germination.
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DEFF Research Database (Denmark)
Om genopførelsen af Palle Nielsens (f. 1942) værk Modellen fra 1968: en kæmpe legeplads til børn i museet, hvor de kan boltre sig frit: klatre i tove, kravle i trækonstruktioner, arbejde med værktøjer, kaste sig ud i skumgummipuder, male med fingermaling og klæde sig ud i kostumer......Om genopførelsen af Palle Nielsens (f. 1942) værk Modellen fra 1968: en kæmpe legeplads til børn i museet, hvor de kan boltre sig frit: klatre i tove, kravle i trækonstruktioner, arbejde med værktøjer, kaste sig ud i skumgummipuder, male med fingermaling og klæde sig ud i kostumer...
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DEFF Research Database (Denmark)
2012-01-01
Leder: "At dele eller ikke dele …" Artikler: "Den lange vej til enhedsskolen". Af Lars Olsen "Enhedsskolen til tælling – en fortælling". Af Jens Rasmussen "Stupid styring eller ”deltagelse, medansvar, rettigheder og pligter” i folkeskolen". Af Verner C. Petersen "Reduktion af presset på specialun......Leder: "At dele eller ikke dele …" Artikler: "Den lange vej til enhedsskolen". Af Lars Olsen "Enhedsskolen til tælling – en fortælling". Af Jens Rasmussen "Stupid styring eller ”deltagelse, medansvar, rettigheder og pligter” i folkeskolen". Af Verner C. Petersen "Reduktion af presset på...
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Energy Technology Data Exchange (ETDEWEB)
Lewis, Amanda [Pall Corporation, Port Washington, NY (United States); Zhao, Hongbin [Pall Corporation, Port Washington, NY (United States); Hopkins, Scott [Pall Corporation, Port Washington, NY (United States)
2014-12-01
This report summarizes the work completed under the U.S. Department of Energy Project Award No.: DE-FE0001181 titled “Designing and Validating Ternary Pd Alloys for Optimum Sulfur/Carbon Resistance in Hydrogen Separation and Carbon Capture Membrane Systems Using High-Throughput Combinatorial Methods.” The project started in October 1, 2009 and was finished September 30, 2014. Pall Corporation worked with Cornell University to sputter and test palladium-based ternary alloys onto silicon wafers to examine many alloys at once. With the specialized equipment at Georgia Institute of Technology that analyzed the wafers for adsorbed carbon and sulfur species six compositions were identified to have resistance to carbon and sulfur species. These compositions were deposited on Pall AccuSep® supports by Colorado School of Mines and then tested in simulated synthetic coal gas at the Pall Corporation. Two of the six alloys were chosen for further investigations based on their performance. Alloy reproducibility and long-term testing of PdAuAg and PdZrAu provided insight to the ability to manufacture these compositions for testing. PdAuAg is the most promising alloy found in this work based on the fabrication reproducibility and resistance to carbon and sulfur. Although PdZrAu had great initial resistance to carbon and sulfur species, the alloy composition has a very narrow range that hindered testing reproducibility.
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Profile Septa cut out condensate crud
International Nuclear Information System (INIS)
Poschmann, T.
1991-01-01
Secondary side corrosion is a major factor leading to steam generator tube plugging. Large quantities of steam generator sludge can harden, prolonging system maintenance during an outage. However, eliminating the ingress of solids to the PWR steam generators can reduce the need for sludge lancing and increase the life of the steam generator tubes. The Pall Corporation has developed an improved filter demineralizer septum for retrofitting traditional yarn-wound elements without having to modify hardware. In November 1990, operators at Turkey Point installed 496 2in x 70in Pall's Profile Septa in one of the four filter demineralizer vessels on unit 3. After installation of the Profile Septa, samples of filter influent and effluent were taken and analyzed over a one-month period - these showed a particulate removal rate of 96-99%. Contaminant analysis by Pall Corporation identified the vast majority of particulates to be iron oxides. This is as was expected, since Turkey Point has titanium condenser tubes which reduce the source of copper oxides. The success of Profile Septa at Turkey Point has encouraged the other utilities to look at using the septa at their own plants. The cost for these retrofits would be recouped through savings in maintenance costs, due to faster steam generator lancing (fewer solids), reduced radiation exposure and, ultimately, longer steam generator life. (author)
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Energy Technology Data Exchange (ETDEWEB)
Hortigóna, B.; Gallardo, J.M.; Nieto-García, E.J.; López, J.A.
2017-09-01
The elastoplastic behaviour of steel used for structural member fabrication has received attention to facilitate a mechanical-resistant design. New Zealand and South African standards have adopted various theoretical approaches to describe such behaviour in stainless steels. With respect to the building industry, describing the tensile behaviour of steel rebar used to produce reinforced concrete structures is of interest. Differences compared with the homogenous material described in the above mentioned standards and related literatures are discussed in this paper. Specifically, the presence of ribs and the TEMPCORE® technology used to produce carbon steel rebar may alter the elastoplastic model. Carbon steel rebar is shown to fit a Hollomon model giving hardening exponent values on the order of 0.17. Austenitic stainless steel rebar behaviour is better described using a modified Rasmussen model with a free fitted exponent of 6. Duplex stainless steel shows a poor fit to any previous model. [Spanish] Uno de los principales factores tenidos en cuenta en la fabricación de aceros estructurales es su comportamiento durante la fase elastoplástica o de endurecimiento por deformación. Normas neozelandesas y sudafricanas plantean diversas aproximaciones teóricas para describir dicho comportamiento en el caso de los aceros inoxidables. En el campo de la construcción resulta de interés la descripción del comportamiento tenso-deformacional de los aceros corrugados utilizados en las estructuras de hormigón armado. En este artículo se discuten los modelos planteados en las normas citadas anteriormente así como los existentes en la literatura tanto para los aceros corrugados inoxidables como para los aceros al carbono fabricados mediante el proceso denominado TEMPCORE® Los aceros TEMPCORE® analizados arrojan un valor del exponente de endurecimiento por deformación según el modelo de Hollomon de 0.17. Los aceros inoxidables austeníticos se ajustan mejor al modelo
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Hummel, Jonathan; Pagkaliwangan, Mark; Gjoka, Xhorxhi; Davidovits, Terence; Stock, Rick; Ransohoff, Thomas; Gantier, Rene; Schofield, Mark
2018-01-17
The biopharmaceutical industry is evolving in response to changing market conditions, including increasing competition and growing pressures to reduce costs. Single-use (SU) technologies and continuous bioprocessing have attracted attention as potential facilitators of cost-optimized manufacturing for monoclonal antibodies. While disposable bioprocessing has been adopted at many scales of manufacturing, continuous bioprocessing has yet to reach the same level of implementation. In this study, the cost of goods of Pall Life Science's integrated, continuous bioprocessing (ICB) platform is modeled, along with that of purification processes in stainless-steel and SU batch formats. All three models include costs associated with downstream processing only. Evaluation of the models across a broad range of clinical and commercial scenarios reveal that the cost savings gained by switching from stainless-steel to SU batch processing are often amplified by continuous operation. The continuous platform exhibits the lowest cost of goods across 78% of all scenarios modeled here, with the SU batch process having the lowest costs in the rest of the cases. The relative savings demonstrated by the continuous process are greatest at the highest feed titers and volumes. These findings indicate that existing and imminent continuous technologies and equipment can become key enablers for more cost effective manufacturing of biopharmaceuticals. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
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International Nuclear Information System (INIS)
Dijk, G. van; Smit, W.A.
1977-01-01
This report is a sequel to the previous Boerderijcahier (no. 7502) which discussed long-term effects of soil contamination in case of a nuclear power plant accident. In this report the short-term health effects are discussed. Models describing the local consequences of a severe accident are developed, taking into account the possible weather conditions (meteorological model), the evacuation possibilities and the inhabitability of certain areas. In each case long-term and short-term effects are discussed. The safety studies by various departments of the Netherlands' government and the Rasmussen report are commented on
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A study of the various baffles used in the Marcoule chimneys and the search for a new model (1961)
International Nuclear Information System (INIS)
Chassany, J.; Salaun-Penquer, G.
1961-01-01
The baffle placed at the top of a chimney determines the shape of the smoke pall for low exit-velocities. The G. 1 type baffle was studied taking into account the characteristics of its collar: totally hollow - partially hollow - solid; on a ribbed chimney or on a plain chimney. The Pu type baffle was also tested. The search for a new type of baffle was limited to variants of the blade - type baffle: - a porous envelope device; - a cone - shaped device and - a deflector of the cupel type. Only the blade-type baffle was rejected, efficient solutions are proposed using the other types or their combinations. (authors) [fr
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Eesti Energia nõukogu liikmed Jaotusvõrgu hinnatõusutaotlust kommenteerima ei kipu / Katre Pilvinski
Pilvinski, Katre
2010-01-01
Eesti Energia nõukogu liige Kalle Palling kommenteerib peaminister Andrus Ansipi öeldut, et Eesti Energia investeeringud tuleb üle vaadata. Nõukogu liikme Rein Kilgi sõnul tunduvad talle rünnakud Eesti Energia vastu ülekohtused
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U.S. EPA, Pesticide Product Label, , 12/29/1972
2011-04-14
... Ion Is • slroltl dIoIilltl .... inltibitar ..... 6 Jetl r . f'triplt,raf ""UI systeMs .. ".11 tI. CIr· ~c: ilild rnpillt., ... At l1li lilt " pallIIOIIIty vde'llll, .... 1 .lul ..... SI' .... ...
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Oxygen diffusion in fish embryos
Kranenbarg, S.
2002-01-01
<p>All vertebrate embryos pass through a developmental period of remarkably low morphological variability. This period has been called phylotypic period. During the phylotypic period, organogenesis takes place, including blood vessel development. Before the phylotypic
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Haridusvabadus / ajakirjast "The Freeman" tlk. Riinu Pall
2000-01-01
Praegune haridussüsteem on vastuolus individuaalse vabaduse ja vastutuse põhimõtetega vabas ühiskonnas, hariduse kvaliteedi tõstmise asemel on süsteemis madal tase ja ebatõhus vahendite kasutamine
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An Alternative Approach to the Variable Housing Allowance Program
1987-01-01
Chamber of Commerce Researchers Association. "Inter-City Cost of Living Indicators." Indianapolis, Fourth Quarter, 1985. Deaton, Angus S. "The Analysis of Consumer Demand in the United Kingdom, 1900-1970." Econometrica, 42, No. 2 (1974), pp. 341-367. 9 Models and Projections of Demand in Past-War Britain. London: Chapman and Hall, 1975. Haworth, C. T. and D. W. Rasmussen. "Determinants of Metropolitan Cost of Living Variations." Southern Economic Journal, 40, No. 2 (1973), pp. 183-192. Stone,
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2013-10-03
..., Hartford, CT. Inc., Corporate/Finance/ Controllers. The following determinations terminating investigations... Staffing, Employee Management, CBS Personnel, etc. 82,977 Pall Corporation, Finance Port Washington, NY..., Greensboro, NC. Finance Department, Novartis AG, ProUnlimited. 82,984 The Berry Company, LLC Rochester, NY...
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Hudozhniki ubirali les / Alina Zelimhanova
Zelimhanova, Alina
2003-01-01
Fotonäitus "Kirju pall" Eesti Kunstiakadeemia galeriis on pühendatud hoolitsusele looduse puhtuse eest. Näituse avamise järel suundusid kunstnikud Pääsküla metsa prügi koristama. Näituse korraldaja Piret Räni selgitus
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Yellin's review of the Nuclear Regulatory Commission's Reactor Safety Study: comment
International Nuclear Information System (INIS)
Wilson, R.
1976-01-01
Joel Yellin (Bell J. Economics, Vol. 7, No. 1 (Spr. 1976)) reviewed the Reactor Safety Study (WASH-1400, or Rasmussen Report) published by the Nuclear Regulatory Commission and makes several criticisms. Wilson finds that some of these criticisms are much overstated, while others, although valid, are mainly criticisms of presentation. To be useful for public policy, reactor risks--and indeed all nuclear risks--must be compared with other risks society faces. Wilson feels that the Rasmussen Report is weak in these comparisons, primarily because there exist few estimates of risk in other places, but that the comparisons he does make indeed confirm that the risk is smaller than Yellin suggests. 20 references
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Directory of Open Access Journals (Sweden)
Birgitta Nordström
2016-12-01
Full Text Available My current research focuses on textiles and rites, especially woven textiles for funerals and moments of loss. What active role can a textile such as an infant-wrapping cloth or a funeral pall play in the mourning process? This article will describe the development and current questions that address 1 the infant-wrapping cloth – the textile that is used to dress, clothe, or cover the dead body with particular attention to the question of infant mortality and the material practices of care. 2 The funeral pall that is used at funerals, draped over the coffin or as a body cover at hospital viewing rooms. One example to be presented is Kortedalakrönika (‘The Chronicle of Kortedala’, a collaborative project, woven for a church in Gothenburg. My work is based in artistic practice but opens up several scientific and existential questions.
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MONEY TRANSFERS VIA ONLINE PLATFORMS - LOGISTICS FOR BUSINESS DEVELOPMENT
Directory of Open Access Journals (Sweden)
CLAUDIA ISAC
2016-10-01
Full Text Available In this paper I have presented 3 of the money transfer platforms which operate via the Internet. The development of the Internet, electronic commerce and money transfers due to international migration and movement of people directly determines the improvement of money transfer processes, so as to find the best tools for money transfers at minimum costs and high transfer speeds, implying secure trading and personal data privacy. In this context I have compared the three most frequently used trading platforms PayPall, transferGo, TransferWise, also including a presentation of each of them. I have also done a more detailed analysis of the evolution of PayPall in Romania and on the international market due to the high amounts of money and the number of transactions. I have completed the work with a brief presentation of the financial trends and especially of trading via the Internet.
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Rasmussen's encephalitis | Dawodu | Nigerian Journal of Clinical ...
African Journals Online (AJOL)
complicated meningo.encephalitis and the third episode was associated with receptive aphasia, hemiparesis and intellectual impairment. Neuroimaging studies revealed cerebellar atrophy and infarction of territory of the middle cerebral artery.
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The role of environmental shocks in shaping prosocial behavior
Duchoslav, Jan
2017-01-01
<p>All economic activity requires some degree of cooperation, and the process of economic development involves many social dilemmas. It is therefore crucial to understand how the preferences which guide our behavior vis-à-vis these situations are shaped. The ability and willingness to work for the
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Molenaar, J.A.
2015-01-01
Summary
<p>All plants are able to respond to changes in their environment by adjusting their morphology and metabolism, but large differences are observed in the effectiveness of these responses in the light of plant fitness. Between and within species large differences are -
Hydrodynamic behaviour of a gas—solid counter-current packed column at trickle flow
Roes, A.W.M.; van Swaaij, Willibrordus Petrus Maria
1979-01-01
Trickle flow of a more or less fluidized catalyst through a packed column is a promising new gas—solid counter-current operation. The hydrodynamic, behaviour of such a column, filled with dumped PALL rings, has been investigated, while some results have been obtained with RASCHIG rings and
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Proposal to conserve Tamarix ramosissima against T. pentandra Tamaricaceae)
Ledebour described Tamarix ramosissima in 1829 from plants collected in Kazakhstan (Lake Noor Zaisan). In the protologue he overlooked T. pentandra Pall. (l.c.) and T. pallasii Desv. (l.c.), two earlier names which apply to the same biological entity, also widespread through Central and Western Asia...
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Mõtlejate mõjud ja sotsiaalne aktsionism Tallinna galeriides / Margaret Tali
Tali, Margaret
2002-01-01
Marko Laimre näitus "Must pall" Tallinna Kunstihoones, Liina Siibi näitus "Klips" (plakatid, videod) Hansapanga galeriis, Stuudio 22 näitus "déja vu" (graafika) Pärnu mnt. 27 galeriis, Eesti Kunstiakadeemia üliõpilaste joonistused "Tühjus ja Ruum" G-galeriis
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NATO chief arrives to discuss alliance's new strategy / Ella Karapetyan
Karapetyan, Ella
2009-01-01
8. oktoobril Eestis visiidil viibinud NATO peasekretär Anders Fogh Rasmussen kohtus president Toomas Hendrik Ilvese ja välisminister Urmas Paetiga. Teemadeks oli Afganistanis toimuv, NATO ja viimase suhted Venemaaga
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Alhumaidan, Hiba; Cheves, Tracey; Holme, Stein; Sweeney, Joseph D
2011-10-01
The processing of whole blood-derived platelet-rich plasma (PRP) to a platelet concentrate and platelet-poor plasma is currently performed within 8 hours to comply with the requirements to manufacture fresh frozen plasma. Maintaining PRP at room temperature for a longer period can have the advantage of shifting the completion of component manufacture onto day shifts. Pairs of ABO-identical prepooled platelets were manufactured by the PRP method, using the current approach with platelet storage in a CLX HP container (Pall Medical, Covina, CA) and plasma, or a novel approach with an 18- to a 24-hour room temperature hold of the PRP and the manufacture of pooled platelets in a glucose-containing additive solution (AS) and storage in a new ELX container (Pall Medical). Standard in vitro assays were performed on days 2, 5, and 7. The results showed that the AS platelets in ELX have in vitro characteristics that are equivalent or superior to those of the standard product.
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South-East Region in Bulgaria: Economic Performance and Key Sectors Analysis
Directory of Open Access Journals (Sweden)
Antoaneta GOLEMANOVA
2008-01-01
Full Text Available The present paper attempts to provide insight into the economicperformance of the South-east region (SER of Bulgaria by presenting quantitativerelationships between sectors in the regional economy. Methodologically it is basedon the construction of the regional Input–Output model. It was carried out troughapplying the non-servey GRIT technique, based on Flegg & Webber locationquotient (2000. The dirived Rasmussen & Hirschman backward linkages andMattas & Shrestha input-output elasticities from the model enable to identify thekey economic sectors within the region. This could be considered as a starting pointfor the future impact assesment of different EU policies, as well as designing ofbetter regional development strategies, assuring better economic performance.
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In vivo activities of Baicalin against Chlamydia trachomatis
African Journals Online (AJOL)
USER
2010-03-15
Rasmussen et al., 1997). The infectivity of the chlamydia was expressed as the number of inclusion forming units. Baicalin (HPLC Content > 98.0%) from Chongqing Green Valley. Bio-tech Co. LTD. (Chongqing, China).
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Impact of sophisticated fog spray models on accident analyses
International Nuclear Information System (INIS)
Roblyer, S.P.; Owzarski, P.C.
1978-01-01
The N-Reactor confinement system release dose to the public in a postulated accident is reduced by washing the confinement atmosphere with fog sprays. This allows a low pressure release of confinement atmosphere containing fission products through filters and out an elevated stack. The current accident analysis required revision of the CORRAL code and other codes such as CONTEMPT to properly model the N Reactor confinement into a system of multiple fog-sprayed compartments. In revising these codes, more sophisticated models for the fog sprays and iodine plateout were incorporated to remove some of the conservatism of steam condensing rate, fission product washout and iodine plateout than used in previous studies. The CORRAL code, which was used to describe the transport and deposition of airborne fission products in LWR containment systems for the Rasmussen Study, was revised to describe fog spray removal of molecular iodine (I 2 ) and particulates in multiple compartments for sprays having individual characteristics of on-off times, flow rates, fall heights, and drop sizes in changing containment atmospheres. During postulated accidents, the code determined the fission product removal rates internally rather than from input decontamination factors. A discussion is given of how the calculated plateout and washout rates vary with time throughout the analysis. The results of the accident analyses indicated that more credit could be given to fission product washout and plateout. An important finding was that the release of fission products to the atmosphere and adsorption of fission products on the filters were significantly lower than previous studies had indicated
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Axial dispersion of gas and solid phases in a gas—solid packed column at trickle flow
Roes, A.W.M.; van Swaaij, Willibrordus Petrus Maria
1979-01-01
Axial dispersion of gas and solid phases in a gas—solid packed column at trickle flow, a promising new countercurrent operation, was evaluated using residence time distribution (RTD) experiments. The column was packed with dumped Pall rings, the gas phase was air at ambient conditions and the solid
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Effects of drought and salt stress on seed germination of three ...
African Journals Online (AJOL)
The seeds of Medicago sativa (L.), Astragalus adsurgens (Pall.) and Coronilla varia (L.) were evaluated at germination for tolerance to salt (NaCl) and drought conditions induced by polyethylene glycol (PEG) in an experiment of orthogonal design. The results reveal that the germination percentages of M. sativa and A.
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Woudstra, C.; Skarin, A.; Anniballi, F.; Fenicia, F.; Bano, L.; Drigo, I.; Koene, M.G.J.; Bäyon-Auboyer, M.H.; Buffereau, J.P.; Medici, D.; Fach, P.
2012-01-01
Clostridium botulinum types C and D, as well as their mosaic variants C-D and D-C, are associated with avian and mammalian botulism. This study reports on the development of low-density macroarrays based on the GeneDisc cycler platform (Pall-GeneDisc Technologies) applied to the simultaneous
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International conference "Cultural Plurality in Estonia : Policies and Solutions"
2000-01-01
Ettekandjad: Katrin Saks, Mall Hellam, Mati Luik, Kirsti Häkkinen, Vello Pettai, Ivi Proos, Katri Raik, NiinaOrhimenko, Ib Ostergaard Rasmussen, Urve Läänemets, Jüri Valge, Aleksander Dusman, Raivo Juurak, Rein Ruutsoo
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Sotsiaaluuringud aitavad juhtida perepoliitikat / Kati Karelson, Katre Pall
Karelson, Kati
2003-01-01
Riiklikust perepoliitikast, selle tulemuste analüüs ja võrdlus teistes Euroopa riikides rakendatud institutsionaalsete meetmetega. Artikkel põhineb Euroopa Komisjoni 5. raamprogrammi projektina rahastatud ja aastail 2000-2003 korraldatud uuringu IPROSEC tulemustel. Skeemid. Tabel
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African Journals Online (AJOL)
ebutamanya
2015-01-30
Jan 30, 2015 ... comorbidities, symptoms, CM used, injection mode, site and rate, extravasated volume, location .... extravasated CM volume, application of ice packs, alcoholized .... Miles SG, Rasmussen JF, Litwiller T, Osik A. Safe use of an.
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Kontseptuaalne ja liikumispõhine nüüdistants Täiskuu tantsufestivalil Soomes / Evelin Lagle
Lagle, Evelin, 1986-
2010-01-01
Tantsufestivalist "Täudenkuun Tanssit" (Full Moon Dance Festival). Tantsulavastustest - Tommi Kitti "Riff", Jyrki Karttuneni "Situation Room", Kenneth Kvanströmi "Destruction Song", Liisa Petti "Mabel or the Gueen of Bones", Elina Pirineni "A Friend of the Pianist", Johanna Tuukkaneni "Outstanding Performance" ja Palle Granhoj sooloetendus "(...It's a Very Big Secret...)"
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DEFF Research Database (Denmark)
Woudstra, C.; Skarin, H.; Anniballi, F.
2013-01-01
Two real-time PCR arrays based on the GeneDisc® cycler platform (Pall-GeneDisc Technologies) were evaluated in a multicenter collaborative trial for their capacity to specifically detect and discriminate Clostridium botulinum types C, D and their mosaic variants C-D and D-C that are associated wi...
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African Journals Online (AJOL)
Proff.Adewunmi
Belamcanda chinensis includes only one species in China. The genus is widespread in Jilin, Liaoning, Hebei, Shanxi and Shandong provinces (Huang, 2010). In some districts, Iris dichotoma Pall (also known as the wild iris) and Iris tectorum maxim (also known as Chuan Iris) are substituted for Belamcanda chinensis (Qin ...
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Treatment Failure for Malaria in Vietnam
Centers for Disease Control (CDC) Podcasts
2017-06-05
WHO malaria expert, Dr. Charlotte Rasmussen, discusses anti-malarial drug resistance in Vietnam. Created: 6/5/2017 by National Center for Emerging and Zoonotic Infectious Diseases (NCEZID). Date Released: 6/5/2017.
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Unusual rainfall shift during monsoon period of 2010 in Pakistan ...
African Journals Online (AJOL)
Arslan
2013-09-04
Sep 4, 2013 ... Key words: Indus River, monsoon, flooding in 2010, rainfall pattern, Climate ... data was plotted in excel sheet with upper and lower limits defined .... Houze Jr, Rasmussen R, Medina K, Brodzik S, Romatschke SU (2011).
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Väikeste ridamajade rida Kloostrimetsas = A Row of Little Row Houses in Kloostrimetsa / Urmas Oja
Oja, Urmas, 1981-2012
2003-01-01
Neljast ridaelamust, millest kaks on propjekteerinud Ado Eigi (Ado Eigi Arhitektuuribüroo, konstruktsioonid: Uno Pall, projekt 2002, valminud 2003), ühe Ott Kadarik ja Mihkel Tüür (COO Arhitektid, projekt 2002, valminud 2003) ning ühe arhitektuuribüroo Kosmos (valminud 2004). Sisevaade, 6 välisvaadet, 5 korruste plaani
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Strategic Design as Agile Driver in Innovating SME´s
DEFF Research Database (Denmark)
Ludvigsen, Martin; Rasmussen, Jørgen
2012-01-01
of strategic design must be based on actual ongoing processes in live business cases in order to be relevant to a wider audience. The value of purely speculative strategic design research reflections is diminishing as the research field is maturing and solidifying. The work reported in this paper highly......Strategic Design as Agile Driver in Innovating SME´s Poster-paper abstract, DMI2012 conference Martin Ludvigsen and Jørgen Rasmussen Aarhus School of Architecture, Department of Design Nørreport 20, 8000 Aarhus C, Denmark martin.ludvigsen@aarch.dk, jorgen.rasmussen@aarch.dk The paper reports...... on the last four years of research into strategic design (SD) at Aarhus School of Architecture, Denmark. Under the heading of organizational change and business development through design and user driven value identification, the authors have conducted a range of practice-based SD research projects engaging...
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Exploring the design space of shape-changing objects
DEFF Research Database (Denmark)
Nørgaard, Mie; Merritt, Timothy Robert; Rasmussen, Majken
2013-01-01
In this paper we describe the outcomes from a design exercise in which eight groups of designers designed and built hardware sketches in the form of playful shape-changing prototypes, generatively working with Rasmussen et al's [31] eight unique types of shape change. Seeing that shape-changing i......In this paper we describe the outcomes from a design exercise in which eight groups of designers designed and built hardware sketches in the form of playful shape-changing prototypes, generatively working with Rasmussen et al's [31] eight unique types of shape change. Seeing that shape...... for the further expansion of the design space of shape changing interfaces relating to the perception and understanding of behaviour, causality and the mechanics involved in shape change events, which we call "Imagined Physics." This concept is described along with additional insights into the qualities of shape...
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CARDIOVASCULAR DISORDERS AMONG PERSONS WITH DOWN SYNDROME
Vis, Jeroen C.; van Engelen, Klaartje; Bouma, Berto J.; Bilardo, Catia M.; Blom, Nico A.; Mulder, Barbara J. M.
2010-01-01
Down syndrome is the most common chromosomal abnormality among liveborn infants and is the most frequent chromosomal cause of intellectual disability (Frid, Drott, Lundell, Rasmussen, & Anneren, 1999). It is a multisystem disorder, characterized by various congenital defects, organic disorders,
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Antiphospholipid antibodies in children and adolescents with epilepsy
African Journals Online (AJOL)
Ehab
the role of autoimmunity in the pathogenesis of epilepsy ... Background: Some immunologic mechanisms of epilepsy are cited in literature. ... Objective: This study investigates the prevalence of some antiphospholipid .... brain and in some cases magnetic resonance imaging .... DISCUSSION .... Rasmussen's encephalitis.
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DEFF Research Database (Denmark)
Kristensen, Dorthe Riis; Leegaard, Sarah Palle
2017-01-01
Sarah Palle Leegaard og Dorthe Riis Kristensen indleder deres artikel ”Pædagogisk improvisation” med at konstatere, at ”begrebet pædagogisk improvisation er en definition på pædagogens grundlæggende faglighed på højde med det at trække vejret”. Når vi trækker vejret ind, tager vi dét til os, som...... pædagogisk improvisation er udviklet i forbindelse med et forskningsprojekt, hvor Sarah Palle Leegaard og Dorthe Riis Kristensen har fokus på det, de betegner som pædagogens upåagtede faglighed i skoleregi. Hensigten er at udvikle en tydelig fagforskel i henholdsvis lærer- og pædagogprofessionen med henblik...... på at styrke samarbejdet. På baggrund af undersøgelser i praksis i form af bl.a. interviews med lærere og pædagoger, iagttagelser af situationer fra samarbejdet i klasserummet samt oplæg og praktiske øvelser i pædagogisk improvisation (dans) redegør artiklen for, hvordan de deltagende lærere og...
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DEFF Research Database (Denmark)
Rasmussen, Mattias Borg; Lund, Christian
2018-01-01
The global expansion of markets produces frontiers of contestation over the definition and control of resources. In a frontier context, new patterns of resource exploration, extraction, and commodification create new territories. A recently published collection (Rasmussen and Lund 2018) explores...
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DEFF Research Database (Denmark)
Schow, Trine; Harris, Paul; Teasdale, Thomas William
2016-01-01
Trine Schow, Paul Harris, Thomas William Teasdale, Morten Arendt Rasmussen. Evaluation of a four month rehabilitation program for stroke patients with balance problems and binocular visual dysfunction. NeuroRehabilitation. 2016 Apr 6;38(4):331-41. doi: 10.3233/NRE-161324....
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Astronaut observations of global biomass burning
International Nuclear Information System (INIS)
Wood, C.A.; Nelson, R.
1991-01-01
One of the most fundamental inputs for understanding and modeling possible effects of biomass burning is knowledge of the size of the area burned. Because the burns are often very large and occur on all continents (except Antarctica), observations from space are essential. Information is presented in this chapter on another method for monitoring biomass burning, including immediate and long-term effects. Examples of astronaut photography of burning during one year give a perspective of the widespread occurrence of burning and the variety of biological materials that are consumed. The growth of burning in the Amazon region is presented over 15 years using smoke as a proxy for actual burning. Possible climate effects of smoke palls are also discussed
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Total glucosides of peony attenuates experimental autoimmune encephalomyelitis in C57BL/6 mice.
Huang, Qiling; Ma, Xiaomeng; Zhu, Dong Liang; Chen, Li; Jiang, Ying; Zhou, Linli; Cen, Lei; Pi, Rongbiao; Chen, Xiaohong
2015-07-15
Total glucosides of peony (TGP), an active compound extracted from the roots of Paeonia lactiflora Pall, has wide pharmacological effects on nervous system. Here we examined the effects of TGP on experimental autoimmune encephalomyelitis (EAE), an established model of multiple sclerosis (MS). The results showed that TGP can reduce the severity and progression of EAE in C57 BL/6 mice. In addition, TGP also down-regulated the Th1/Th17 inflammatory response and prevented the reduced expression of brain-derived neurotrophic factor and 2',3'-cyclic nucleotide 3'-phosphodiesterase of EAE. These findings suggest that TGP could be a potential therapeutic agent for MS. Copyright © 2015 Elsevier B.V. All rights reserved.
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Eestlaste pension kinnisvaraturu meelevallas / Anne Oja
Oja, Anne, 1970-
2007-01-01
Ilmunud ka: Delovõje Vedomosti 22. aug. lk. 6. Eesti pensionifondid on kinnisvarasse paigutanud umbes miljard krooni. Kinnisvarafirmade võlakirjade hind võib kujuneda madalaks. Pankade kommentaarid. Vt. samas: Tulevased pensionärid magavad rahulikult. Tabel: Pensionifondide investeeringud kinnisvarasse. Kommenteerivad: Ingmar Mattus, Kalle Palling, Karoli Hindriks, Pertti Rahnel, Andre Nõmm, Urmas Laur, Kristjan Lepik. Kommentaarid ainult eestikeelse art. juures
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Observational Searches for Chromospheric g-Mode Oscillations ...
Indian Academy of Sciences (India)
Pallé (1991) had discussed in great detail the various methods to search for solar gravity modes. Many authors have claimed, in the past 22 years, to detect internal g-modes in the Sun, but so far, there is no observational evidence. The atmospheric g-modes of small scale may exist, but in the atmosphere the Brunt.
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Antibodies to voltage-gated potassium and calcium channels in epilepsy.
Majoie, H.J.; Baets, M.H.V. de; Renier, W.O.; Lang, B.; Vincent, A.
2006-01-01
OBJECTIVE: To determine the prevalence of antibodies to ion channels in patients with long standing epilepsy. BACKGROUND: Although the CNS is thought to be protected from circulating antibodies by the blood brain barrier, glutamate receptor antibodies have been reported in Rasmussen's encephalitis,
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Multimodal pain management after arthroscopic surgery
DEFF Research Database (Denmark)
Rasmussen, Sten
Multimodal Pain Management after Arthroscopic Surgery By Sten Rasmussen, M.D. The thesis is based on four randomized controlled trials. The main hypothesis was that multimodal pain treatment provides faster recovery after arthroscopic surgery. NSAID was tested against placebo after knee arthroscopy...
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The safety of nuclear power plants
International Nuclear Information System (INIS)
Berg, J.O.
1980-01-01
A general presentation is given of reactor safety philosophy and risk analysis. The Rasmussen report (WASH-1400) is discussed and also the Lewis Commission's evaluation of that report. The future developments in reactor safety technology are outlined with emphasis on quality assurance. (JIW)
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Probability and consequences of severe reactor accidents. 60th year atw
Energy Technology Data Exchange (ETDEWEB)
Rasmussen, Norman Carl [Massachusetts Institute of Technology (MIT), Cambridge, MA (United States). Dept. of Nuclear Engineering
2015-06-15
The study carried out on behalf of former USAEC (United States Atomic Energy Commission) led by Prof. Rasmussen and published in reworked form as WASH 1400 by the USNRC (United States Nuclear Regulatory Commission) in 1975, assessed in 3,300 pages the risks that can be deducted from severe accidents in nuclear power plants. The results, often quoted and criticised, were so far the most conclusive statements to this question. In his lecture at the reactor meeting in 1976, Prof. Rasmussen tried to trace back the conclusion of the results to the question: Is the use of larger nuclear power plants, in accordance to experiences and calculations so far, acceptable? His risk assessment, related to American power plants and cites, on behalf of the BMI is currently evaluated by the IRS together with the LRA on specific occurrences within the Federal Republic of Germany.
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Exploring the Design Space of Shape-Changing Objects
DEFF Research Database (Denmark)
Merritt, Timothy; Petersen, Marianne Graves; Nørgaard, Mie
2015-01-01
In this paper we describe the outcomes from a design exercise in which eight groups of designers designed and built hardware sketches in the form of playful shape- changing prototypes, generatively working with Rasmussen et al’s [31] eight unique types of shape change. Seeing that shape-changing ......In this paper we describe the outcomes from a design exercise in which eight groups of designers designed and built hardware sketches in the form of playful shape- changing prototypes, generatively working with Rasmussen et al’s [31] eight unique types of shape change. Seeing that shape...... for the further expansion of the design space of shape changing interfaces relating to the perception and understanding of behaviour, causality and the mechanics involved in shape change events, which we call “Imagined Physics.” This concept is described along with additional insights into the qualities of shape...
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A review of specialist palliative care provision and access across London - mapping the capital.
Cox, Sarah; Murtagh, Fliss E M; Tookman, Adrian; Gage, Andrew; Sykes, Nigel; McGinn, Maureen; Kathoria, Meeta; Wilderspin, Hilary; Chart, Liz
2017-05-01
Palliative care provision varies by diagnosis, geography, and setting. The Minimum Data-set provides high-level data on provision, but comprehensive comparative information about specialist palliative care (SPC) provision is lacking. The London Cancer Alliance - now RM Partners' Accountable Cancer Network - palliative care group (West/South London) and PallE8 (North/East London), with Marie Curie, sought to address this gap. The aim was to provide comparative data on SPC provision across London to support commissioners and providers to assess provision, identify gaps, and reduce inequity. A data-collection template was developed through expert consensus. Demographic, diagnostic, and service data was collected, plus models of care, staffing levels, and use of clinical outcome/experience measures. Results were collated by organisation and CCG. Cleaned data was provided back to each organisation for verification before final analyses. All 50 adult SPC providers in London participated, representing hospitals, hospices and community services. •Patients in all 32 CCGs have access to hospice beds, with 322 beds from 15 providers (4 NHS) for a population of 9,323,570 (with 47,583 deaths annually).•SPC in London sees more non-cancer patients than is reported nationally; 79% of hospital advisory, 74% of community, and 88% of hospice in-patient services have higher proportions of non-cancer patients.•Considerable variation in out-of-hours availability of both hospital SPC and community SPC services across London; only 9 of 30 hospital and 17 of 26 community services provide seven-day visiting.•Wide variation in the models of community-based SPC; proportions of community patients attending day services vary from 1 in 4, to 1 in 17, just 13 CCGs have H@H-type provision, with few Rapid Response or Care Coordination services. This detailed survey demonstrates important gaps in availability and provision of SPC services. Recommendations are made for commissioners and
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DEFF Research Database (Denmark)
Bolt, Mikkel
2014-01-01
Mikkel Bolt Rasmussen argues that we must both continue to identify the revolutionary perspective as a communist one and continue to describe the revolution as a communist revolution. He contributes to the on-going discussion of the revolutionary position by reflecting on the relationship between...
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2011-04-13
...'s Dump Superfund Site. Remedial Investigation and Feasibility Study (RI/FS) The Remedial... Investigation Report and Risk Assessment for both the Spiegelberg and Rasmussen's Dump Superfund sites due to... and operating an on-site pump and treat treatment pilot plant. Construction activities included: site...
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Density Deconvolution With EPI Splines
2015-09-01
Davis Highway, Suite 1204, Arlington, VA 22202–4302, and to the Office of Management and Budget, Paperwork Reduction Project (0704-0188) Washington DC...Patricia Jacobs, Dr. Robert Dell, Dr. Carlos Borges , and Dr. Craig Rasmussen, program officers Captain Jeffrey Hyink, Commander Thor Martinsen
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Total Glucosides of Paeonia lactiflora Pall Suppress Nitric Oxide ...
African Journals Online (AJOL)
iNOS) expression and ... Keywords: Total glucosides, Paeonia lactiflora, Nitric oxide, iNOs, Nuclear factor-κB. Tropical Journal of Pharmaceutical Research ... Nuclear factor (NF)-κB is the key transcriptional factor regulating iNOS gene transcription.
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2003-01-01
EKA galeriis näitusel "Kirju pall" esitavad "krutskilist ökokunsti" rühmitus Puhas Rõõm, Mart Viljus, Anu Vahtra, Maris Mändel, Katrin Tees, Reimo Võsa-Tangsoo, Erki Kasemets, Raivo Hool. Aula fuajees näeb Jaak Soansi juhendamisel valminud skulptuuriosakonna õppetöid, valdavalt poliitikute skulptuurportreid. Osalevad Kristiina Järvelaid, Jelena Levtshenkova, Rene Reinumäe, Kaisa Uusoksa, Marju Vaher
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Cost Effective, Ultra Sensitive Groundwater Monitoring for Site Remediation and Management
2015-05-01
evaporites, sandstone, gravel, conglomerate, and andesitic basalt . Closed basin; playa, alluvial fan, fluvial 600 to 10,000+ Unconfined, leaky...confined Lower unit Breccia, conglomerate, sandstone, siltstone, and local basaltic to rhyolitic flows and pyroclastic rocks. Alluvial fan, fluvial...with large volumes of groundwater. Three of the cartridges additionally protected by glass fiber filters (Acrodisc AP-4523; Pall GmbH, Dreieich, GE
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PICTORIAL INTERLUDE A tale of two embolisations
African Journals Online (AJOL)
leading to vasculitis and thrombosis.[5] The bronchial arteries may enlarge and hypertrophy.[5] Rasmussen aneurysm is a rare complication. (in 5% of autopsied patients with cavitatory tuberculosis[6]) caused by pulmonary artery wall weakening owing to the adjacent cavitatory tuberculosis.[5] Granulation tissue replaces ...
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2009-11-01
modulating neurobio - logical responses to ethanol and drugs of abuse, including the striatum, nucleus accumbens (NAc), ventral tegmental area (VTA...critically required for the regulation of energy homeostasis in mice. Mol Cell Biol 22, 5027–5035. Rasmussen, D.D., Bryant, C.A., Boldt, B.M., Colasurdo
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A MASS BALANCE OF SURFACE WATER GENOTOXICITY IN PROVIDENCE RIVER (RHODE ISLAND USA)
White and Rasmussen (Mutation Res. 410:223-236) used a mass balance approach to demonstrate that over 85% of the total genotoxic loading to the St. Lawrence River at Montreal is non-industrial. To validate the mass balance approach and investigate the sources of genotoxins in sur...
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Directory of Open Access Journals (Sweden)
CC Chan
2012-03-01
Full Text Available The outcome of bicondylar tibial plateau fractures treated with either external fixation (35 patients or internal fixation (24 patients was reviewed. Outcome measures included the Rasmussen score, clinical complications, development of osteoarthritis and the requirement for total knee replacement (TKR. Twenty-two (92% anatomical reductions were achieved in the internal fixation group compared to 27 (77% in the external fixation group. Infective complications were more common in the external fixation group (9 patients, 26% due to pin tract infection. There were no deep infections in the internal fixation group. The mean Rasmussen score was not significantly different (mean score 32 in external fixation and 29 in internal fixation between the two groups and the incidence of osteoarthritis was the same in both groups. Four patients in the external fixation group underwent a TKR compared to 5 patients in the internal fixation group. Bicondylar tibial plateau fractures have similar outcomes following external or internal fixation.
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Elongational viscosity of monodisperse and bidisperse polystyrene melts
DEFF Research Database (Denmark)
Nielsen, Jens Kromann; Rasmussen, Henrik Koblitz; Hassager, Ole
2005-01-01
The startup and steady uniaxial elongational viscosity have been measured for two monodisperse polystyrene melts with molecular weights of 52 kg/mole (PS52K) and 103 kg/mole (PS103K), and for three bidisperse polystyrene melts. The bidisperse melts consist of PS103K or PS52K and a monodisperse...... (closed loop proportional regulator) using the laser in such a way that the stretch rate at the neck is kept constant. The rheometer has been described in more detail in (A. Bach, H.K. Rasmussen and O. Hassager, Journal of Rheology, 47 (2003) 429). PS390K show a decrease in the steady viscosity as a power......-law function of the elongational rate (A. Bach, K. Almdal, H.K. Rasmussen and O. Hassager, Macromolecules 36 (2003) 5174). PS52K and PS103K show that the steady viscosity has a maximum that is respectively 100% and 50% above 3 times the zero-shear-rate viscosity. The bidisperse melts show a significant...
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Is nuclear energy safe for workers and the public. II
International Nuclear Information System (INIS)
Rasmussen, N.
1976-01-01
Dr. Rasmussen first examines the safety and economics records of nuclear power and finds them unassailable. Since these two items could not cause dissension, he observes that dissension evolves from safety of the power plant itself, the issue of diversion to use nuclear materials to make weapons, and from the disposal of wastes. He reviews how radioactivity can be released to cause an accident, and then cites figures comparing accidents each year in the U.S. with those projected for nuclear accidents. To date, not one person has been killed with the operation of a nuclear power plant. Dr. Rasmussen believes that taking advantage of nuclear power far outweighs its risks since ''we have seen what unemployment at the level of 9 or 10 percent has done in this country...to go without power that our industrial society needs to provide livelihood for our citizens will almost surely result in something much more dramatic than that.''
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Probabilistic safety analysis of the containment spray system of Angra-1 reactor
International Nuclear Information System (INIS)
Gibelli, S.M.O.
1981-02-01
The calculation of the unavailability of the containment spray system of Angra-1, is done. The referred system has two different modes of operation (injection and recirculation) which were separately studied using the fault tree methodology. Besides equipment and human error failures, the contributions of test, maintenance and common-mode failures have also been considered. The quantitative evaluation was carried out by the computer code SAMPLE, which considers the uncertainties in the failures data and gives a distribution for the top event unavailability. The input data were obtained from the well-known Rasmussen Report. An importance analysis of the basic events of the trees was performed and a study of the viability of some suggestions for system design modification was also conducted. A comparison between the results obtained in this work and the corresponding ones in the Rasmussen Report has shown the fact that the unavailability of both systems are of the same order of magnitude. (Author) [pt
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DEFF Research Database (Denmark)
Rasmussen, Jens
Teacher Expertise: How to improve the relationship between Theory and Practice in Teacher Education Jens Rasmussen, Department of Education, Aarhus University In several studies and reports it has been nailed over and over that teachers’ matter. So this is not the question in this study. The ques......Teacher Expertise: How to improve the relationship between Theory and Practice in Teacher Education Jens Rasmussen, Department of Education, Aarhus University In several studies and reports it has been nailed over and over that teachers’ matter. So this is not the question in this study....... The question is how teacher preparation leads to effective teachers. The study Expert in Teaching paid special attention to the intention of connecting coursework more directly to practice in pre-service teacher education. The overall objective of the study was to strengthen the relationship between theory...... that the three parties (college teachers, practice teachers and teacher students) found it difficult to perform and maintain their different roles....
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DEFF Research Database (Denmark)
Rasmussen, Malin Lundberg
Incidence of diabetic macular edema and associated risk factors in a cohort of patients with type 1 diabetes in Denmark. Rasmussen M.L.1, Pedersen R.B. 1, Sjølie A.K. 1, Grauslund J1 1University of Southern Denmark, Department of ophthalmology, Odense University Hospital, Denmark Purpose: To eval......Incidence of diabetic macular edema and associated risk factors in a cohort of patients with type 1 diabetes in Denmark. Rasmussen M.L.1, Pedersen R.B. 1, Sjølie A.K. 1, Grauslund J1 1University of Southern Denmark, Department of ophthalmology, Odense University Hospital, Denmark Purpose......: To evaluate the 16-year incidence of diabetic macular edema (DME) in a cohort of type 1 diabetic patients and to investigate possible risk factors of developing DME. Methods: This was a prospective cohort study of Danish type 1 diabetic patients. A total of 131 patients were examined at baseline in 1995...
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East and Central African Journal of Surgery Volume 15 Number 2 ...
African Journals Online (AJOL)
DELL
Thyroid Dysfunction among Young Adults in Uganda ... enrolled 100 Undergraduate medical students by invitations through notices and ... An elevated serum TSH concentration is present in both overt and mild hypothyroidism. In .... smoking in this study. ... Nils K, Torben J, Rasmussen S, Christiansen E and Perrild H. The ...
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Indian Academy of Sciences (India)
TECS
2004; Fecht and Johnson 2004). Several experimental techniques for extending the range of observable under- cooling are available (Turnbull 1950a; Turnbull and Cech. 1950; Wang and Smith 1950; Duwez et al 1960; Fehling and Scheil 1962; Shiraishi and Wood 1964; Rasmussen and Loper Jr. 1975; Southin and ...
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African Journal of AIDS Research - Vol 12, No 1 (2013)
African Journals Online (AJOL)
Barriers and facilitators to antiretroviral therapy adherence among patients with HIV in Bissau, Guinea-Bissau: A qualitative study · EMAIL FULL TEXT EMAIL FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Dlama N Rasmussen, David da Silva Té, Lotte Rodkjaer, Inés Oliveira, Candida Medina, Toke Barfod, ...
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Deficiency of the GPR39 receptor is associated with obesity and altered adipocyte metabolism
DEFF Research Database (Denmark)
Petersen, Pia Steen; Jin, Chunyu; Madsen, Andreas Nygaard
2011-01-01
, conceivably due to decreased energy expenditure and adipocyte lipolytic activity.-Petersen, P. S., Jin, C., Madsen, A. N., Rasmussen, M., Kuhre, R., L. Egerod, K. L., Nielsen, L. B., Schwartz. T. W., Holst, B. Deficiency of the GPR39 receptor is associated with obesity and altered adipocyte metabolism....
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Chiu, Chih-Hao; Cheng, Chun-Ying; Tsai, Min-Chain; Chang, Shih-Sheng; Chen, Alvin Chao-Yu; Chen, Yeung-Jen; Chan, Yi-Sheng
2013-08-01
To present the radiologic and clinical results of posteromedial fractures treated with arthroscopy-assisted reduction and buttress plate and cannulated screw fixation. Twenty-five patients with posteromedial tibial plateau fractures treated by the described technique were included in this study. According to the Schatzker classification, there were 5 type IV fractures (20%), 2 type V fractures (8%), and 18 type VI fractures (72%). The mean age at operation was 46 years (range, 21 to 79 years). The mean follow-up period was 86 months (range, 60 to 108 months). Clinical and radiologic outcomes were scored by the Rasmussen system. Subjective data were collected to assess swelling, difficulty climbing stairs, joint stability, ability to work and participate in sports, and overall patient satisfaction with recovery. Secondary osteoarthritis was diagnosed when radiographs showed a narrowed joint space in the injured knee at follow-up in comparison with the films taken at the time of injury. The mean postoperative Rasmussen clinical score was 25.9 (range, 18 to 29), and the mean radiologic score was 15.8 (range, 10 to 18). All 25 fractures achieved successful union, and 92% had good or excellent clinical and radiologic results. The 3 fracture types did not significantly differ in Rasmussen scores or rates of satisfactory results (P > .05). Secondary osteoarthritis was noted in 6 injured knees (24%). Arthroscopy-assisted reduction with buttress plate and cannulated screw fixation can restore posteromedial tibial plateau fractures of the knee with well-documented radiographic healing, good clinical outcomes, and low complication rates. Level IV, therapeutic case series. Copyright © 2013 Arthroscopy Association of North America. Published by Elsevier Inc. All rights reserved.
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Trends of air pollution in Denmark - Normalised by a simple weather index model
International Nuclear Information System (INIS)
Kiilsholm, S.; Rasmussen, A.
2000-01-01
This report is a part of the Traffic Pool projects on 'Traffic and Environments', 1995-99, financed by the Danish Ministry of Transport. The Traffic Pool projects included five different projects on 'Surveillance of the Air Quality', 'Atmospheric Modelling', 'Atmospheric Chemistry Modelling', 'Smog and ozone' and 'Greenhouse effects and Climate', [Rasmussen, 2000]. This work is a part of the project on 'Surveillance of the Air Quality' with the main objectives to make trend analysis of levels of air pollution from traffic in Denmark. Other participants were from the Road Directory mainly focusing on measurement of traffic and trend analysis of the air quality utilising a nordic model for the air pollution in street canyons called BLB (Beregningsmodel for Luftkvalitet i Byluftgader) [Vejdirektoratet 2000], National Environmental Research Institute (HERI) mainly focusing on. measurements of air pollution and trend analysis with the Operational Street Pollution Model (OSPM) [DMU 2000], and the Copenhagen Environmental Protection Agency mainly focusing on measurements. In this study a more simple statistical model has been developed for trend analysis of the air quality. The model is filtering out the influence of the variations from year to year in the meteorological conditions on the air pollution levels. The weather factors found most important are wind speed, wind direction and mixing height. Measurements of CO, NO and NO 2 from three streets in Copenhagen have been used, these streets are Jagtvej, Bredgade and H. C. Andersen's Boulevard (HCAB). The years 1994-1996 were used for evaluation of the method and annual indexes of air pollution index dependent only on meteorological parameters, called WEATHIX, were calculated for the years 1990-1997 and used for normalisation of the observed air pollution trends. Meteorological data were taken from either the background stations at the H.C. Oersted - building situated close to one of the street stations or the synoptic
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Elevers læring gennem undersøgelse og faglig læsning
DEFF Research Database (Denmark)
Negendahl, Kim; Daugbjerg, Peer
2014-01-01
Med afsæt i Prof. Jens Rasmussens (2013) argumenter for undervisningsdifferentiering vha. præstationsstandarder behandles differentiering af naturfagsundervisnings målsætning for alle skolens elever. Fokus vil være på læreres arbejde med undervisningsplaner og opstillede mål i forhold til undervi...
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The Ellen DeGeneration: Nudging Bias in the Creative Arts Classroom
Harris, Anne
2013-01-01
Research in the areas of lesbian, gay, bisexual, trans and queer (LGBTQ) issues in education has been growing steadily over the past 10 years with the help of Fine and Weis ("Silenced voices and extraordinary conversations: re-imagining schools," 2003), Rasmussen ("Becoming subjects: sexualities and secondary schooling," 2006), Tolman ("Dilemmas…
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What does it mean to say that a hegemonic project is neo-liberal?
DEFF Research Database (Denmark)
Hansen, Allan Dreyer
Udgangspunktet for dette papir er VK-O regeringerne under Anders Fogh Rasmussen i nullerne i Danmark for at rejse spørgsmålet om hvilke teoretiske resurser Laclau og Mouffes hegemoni teori tilbyder, men også hvor yderlig udvikling og nye teoretiske artikulationer er nødvendig. Papiret giver ikke ...
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EVALUATION OF ALTERNATIVE FILTER MEDIA FOR THE ROTARY MICROFILTER
Energy Technology Data Exchange (ETDEWEB)
Poirier, M.; Herman, D.; Bhave, R.
2011-09-13
SRS is currently developing and testing several processes to treat high level radioactive liquid waste. These processes include the Integrated Salt Disposition Process (ISDP), the Salt Waste Processing Facility (SWPF), and the Small Column Ion Exchange Process (SCIX). Each of these processes has a solid-liquid separation process that limits its throughput. SRNL researchers identified and tested the rotary microfilter as a technology to increase solid-liquid separation throughput. The testing showed significant improvement in filter flux with the rotary microfilter over the baseline crossflow filter (i.e., 2.5-6.5X during scoping tests, as much as 10X in actual waste tests, and approximately 3X in pilot-scale tests). SRNL received funding from DOE EM-21, and subsequently DOE EM-31 to develop the rotary microfilter for high level radioactive service. The work has included upgrading the rotary microfilter for radioactive service, testing with simulated SRS waste streams, and testing it with simulated Hanford waste streams. While the filtration rate is better than that obtained during testing of crossflow filters, the authors believe the rotary microfilter throughput can be improved by using a better filter membrane. The rotary microfilter membrane is made of stainless steel (Pall PMM050). Previous testing, funded by DOE EM-21, showed that asymmetric filters composed of a ceramic membrane on top of a stainless steel support produced higher filter flux than 100% stainless steel symmetric filters in crossflow filter tests. In that testing, the Pall Accusep and Graver filters produced 13-21% larger filter flux than the baseline 0.1 {micro}m Mott filter. While the improvement in flux is not as dramatic as the improvement of the rotary filter over a crossflow filter, a 13-21% increase could reduce the lifetime of a 30 year process by 4-6 years, with significant cost savings. Subsequent rotary filter testing showed the Pall PMM050 stainless steel filter membrane produced
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DEFF Research Database (Denmark)
Villadsen, Lisa Storm
2018-01-01
-udmeldingen indebærer for kollektivet. Den anden er statsminister Lars Løkke Rasmussens Grundlovstale 2016. Fra en retorisk medborgerskabsvinkel er det interessant både at statsministeren tager det op, og hvordan han gør det. Visse samfundsfilosoffer, bl.a. John Rawls og Martha Nussbaum har, på linje med retorikken...
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The Global Organic Food Market and Transformation: A Conceptual Theoretical Framework
DEFF Research Database (Denmark)
Rasmussen, Ole Horn
of organic agriculture. In the conclusion the study is presenting a basis for indicators that can be used for comparative studies. It is underlined that the indicators are tentative and that they have to be tested and adjusted in future studies. The report is written by Ole Horn Rasmussen that for four...
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DEFF Research Database (Denmark)
Kjerkegaard, Stefan
endog en selvstigmatisering, hvor selvfortællingen ikke hænger sammen. Der er tale om en menneskelig henvendelse inkorporeret i det, som litteraturen gør, snarere end i det, den siger. I den nye danske litteratur af eksempelvis Yahya Hassan, Asta Olivia Nordenhof eller Bjørn Rasmussen oplever man...
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The 3D Lagrangian Integral Method. Henrik Koblitz Rasmussen
DEFF Research Database (Denmark)
Rasmussen, Henrik Koblitz
2003-01-01
. This are processes such as thermo-forming, gas-assisted injection moulding and all kind of simultaneous multi-component polymer processing operations. Though, in all polymer processing operations free surfaces (or interfaces) are present and the dynamic of these surfaces are of interest. In the "3D Lagrangian...... Integral Method" to simulate viscoelastic flow, the governing equations are solved for the particle positions (Lagrangian kinematics). Therefore, the transient motion of surfaces can be followed in a particularly simple fashion even in 3D viscoelastic flow. The "3D Lagrangian Integral Method" is described...
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Butenko, O M; Staniukovich, M K
2001-01-01
Four new species of the nasal mite family Rhinonyssidae collected in different regions of the former USSR are described: Neonyssus (Otocorinyssus) alaudae sp. n. from Alauda arvensis L. (Alaudidae, Passeriformes) from Turkmenistan; Rhinonyssus clangulae sp. n. from Clangula hyemalis (L.) (Anatidae, Anseriformes) from Yakutia; R. marilae sp. n. from Aythya marilae L. (Anatidae, Anseriformes) from the Russian Far East; Locustellonyssus sibiricus sp. n. from Locustella certhiola (Pall.) (Sylviidae, Passeriformes) from Siberia.
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Sarkiä, P.M.; Adamík, P.; Atemyev, A. V.; Belskii, E.; Both, Christiaan; Burês, S.; Burgess, M.D.; Bushuev, A.V.; Forsman, JT; Grinkov, V.; Hoffmann, D.; Järvinen, A.; Král, M.; Krams, I.; Lampe, H.M.
2015-01-01
Local environmental and ecological conditions are commonly expected to result in local adaptation, although there are few examples of variation in phenotypic selection across continent-wide spatial scales. We collected standardized data on selection with respect to the highly variable plumage coloration of pied flycatcher (Ficedula hypoleucaPall.) males from 17 populations across the species' breeding range. The observed selection on multiple male coloration traits via the annual number of fl...
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The medical elective: A unique educational opportunity | Caldwell ...
African Journals Online (AJOL)
R.I. Caldwell, A.C. Inglis, M. Morgan, K. Rasmussen, C. Aldous. Abstract. No Abstract. Full Text: EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT · AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about ...
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Euroopa majanduste andunud vikatimees Lars Christensen / Piret Reiljan
Reiljan, Piret, 1983-
2007-01-01
Danske Banki vanemanalüütik Lars Christensen on kahtluse alla seadnud Eesti valuutakomitee süsteemi püsimise. Vt. samas: Lars Christensen; Valik Lars Christenseni tänavusi hävitavaid hinnanguid Euroopa murelastele; Islandile kuulutatud häving kukutas otsemaid aktsiaid ja valuutat. Kommenteerivad Lars Rasmussen, Flemming Christensen ja Hanna Strandgaard
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Donovan, Sarah-Louise; Salmon, Paul M; Horberry, Timothy; Lenné, Michael G
2018-01-01
Safety leadership is an important factor in supporting safe performance in the workplace. The present case study examined the role of safety leadership during the Bingham Canyon Mine high-wall failure, a significant mining incident in which no fatalities or injuries were incurred. The Critical Decision Method (CDM) was used in conjunction with a self-reporting approach to examine safety leadership in terms of decisions, behaviours and actions that contributed to the incidents' safe outcome. Mapping the analysis onto Rasmussen's Risk Management Framework (Rasmussen, 1997), the findings demonstrate clear links between safety leadership decisions, and emergent behaviours and actions across the work system. Communication and engagement based decisions featured most prominently, and were linked to different leadership practices across the work system. Further, a core sub-set of CDM decision elements were linked to the open flow and exchange of information across the work system, which was critical to supporting the safe outcome. The findings provide practical implications for the development of safety leadership capability to support safety within the mining industry. Copyright © 2017 Elsevier Ltd. All rights reserved.
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Cheng, Lijuan; Wang, Yanan; Cai, Zhang; Liu, Jie; Yu, Binbin; Zhou, Qixing
2017-03-04
As a green remediation technology, phytoremediation is becoming one of the most promising methods for treating petroleum hydrocarbons (PHCs)-contaminated soil. Pot culture experiments were conducted in this study to investigate phytoremediation potential of two representative Iridaceae species (Iris dichotoma Pall. and Iris lactea Pall.) in remediation of petroleum hydrocarbon-contaminated saline-alkali soil from the Dagang Oilfield in Tianjin, China. The results showed that I. lactea was more endurable to extremely high concentration of PHCs (about 40,000 mg/kg), with a relatively high degradation rate of 20.68%.The degradation rate of total petroleum hydrocarbons (TPHs) in soils contaminated with 10,000 and 20,000 mg/kg of PHCs was 30.79% and 19.36% by I. dichotoma, and 25.02% and 19.35% by I. lactea, respectively, which improved by 10-60% than the unplanted controls. The presence of I. dichotoma and I. lactea promoted degradation of PHCs fractions, among which saturates were more biodegradable than aromatics. Adaptive specialization was observed within the bacterial community. In conclusion, phytoremediation by I. dichotoma should be limited to soils contaminated with ≤20,000 mg/kg of PHCs, while I. lactea could be effectively applied to phytoremediation of contaminated soils by PHCs with at least 40,000 mg/kg.
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Accountability and transparency of financial sector supervision / Pall Gunnar Palsson
Palsson, Pall Gunnar
2001-01-01
Finantsjärelvalve üheks oluliseks tingimuseks on läbipaistvus. Rahvusvahelise Valuutafondi poolt vastu võetud raha- ja rahanduspoliitika heade tavade koodeksist. Ülevaade Islandi finantsinspektsiooni töökorraldusest
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To Be or Not to Be (A Gendered Subject): Was that the Question?
Dillabough, Jo-Anne
2009-01-01
This article presents the author's response to Mary Lou Rasmussen's critical analysis of a piece the author completed in its original form more than a decade ago. She opens this response with the words which Shakespeare gives to Hamlet. There were many reasons why she settled on Hamlet's soliloquy. First, his words stand as a fitting response…
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Rigtige liberale dropper minimalstaten
DEFF Research Database (Denmark)
Bøss, Michael
2006-01-01
I de senere år har vi set, hvordan liberale tænkere er begyndt at revidere de klassiske liberale ideer. Det gælder på fire punkter. I synet på staten, friheden, nationen og "værdierne". Herhjemme er Anders Fogh Rasmussen også sprunget ud - som både socialliberal og konservativ. Udgivelsesdato: 27...
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DEFF Research Database (Denmark)
Littrup, Leif
2009-01-01
Kronik om Maren Kirstine Rasmussen (1893-1937), der var opvokset i Jersore og senere udvandret til USA. Fra 1923 til sin død var hun missionær i Sydkina, udsendt af Aggregation of God (Pinsebevægelsen). Om den Stambog og andet materiale, der er efterladt hos familien i Danmark. [I alt ca. 8...
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Phylogenetic analysis of the genus Anabaena based on PCR ...
African Journals Online (AJOL)
STORAGESEVER
2009-12-15
Dec 15, 2009 ... LTRR2. 5'- CTA TCA GGG ATT GAA AG-3'. Rasmussen and. Svenning, 1998 on a 1% agarose gel containing 0.5 X TBE (Tris Borate-EDTA) and. 0.5 µg/ml ethidium bromide. Data analysis. Fingerprints generated from different Anabaena species were compared and all bands were scored. The presence or ...
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Moving Targets: Constructing Canons, 2013–2014
Hirsch, BD
2015-01-01
This review essay considers early modern dramatic authorship and canons in the context of two recent publications: an anthology of plays -- William Shakespeare and Others: Collaborative Plays (2013), edited by Jonathan Bate and Eric Rasmussen as a companion volume to the RSC Complete Works -- and a monograph study -- Jeremy Lopez's Constructing the Canon of Early Modern Drama (2014).
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A State-of-the-Art Assessment of Automatic Name Placement.
1986-08-01
processing and the annotation problem," Proc. 3rd Scandinavian Conference on Image Analyms, Chartwell-Bratt Ltd., Copenhagen, Denmark, July 1983. This paper...develop an automatic name placement system. 11 Balodis, M., "Positioning of typography on maps," Proc. ACSM Pall Con- vention, Salt Lake City, Utah, Sept...1983, pp. 28-44. This article deals with the selection of typography for maps. It describes psycho-visual experiments with groups of individuals to
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Directory of Open Access Journals (Sweden)
Saulo Varela Della Giustina
2010-09-01
Full Text Available O pós-tratamento de efluentes de reatores anaeróbios é um processo necessário para o atendimento dos padrões de emissão. Os resultados aqui apresentados mostram a viabilidade de uso de uma nova configuração de biofiltro aeróbio submerso (BAS no pós-tratamento desses efluentes. Os BAS multiestágio apresentam uma câmara anaeróbia (V=12,6L, seguido de uma câmara aeróbia (V=30L e uma câmara anóxica (V=26,4L, todas em série (V total=70L. Neste estudo, foi analisada a remoção de sólidos suspensos (SS, DQO e DBO5. Foram utilizados três BAS multi-estágio preenchidos com três diferentes materiais-suporte: tampas e gargalos PET (165m²/m³, pedra britada n. 4 (50m²/m³ e anéis Pall 1,5'' (135m²/m³. Os reatores foram operados com valores de tempos de detenção hidráulicas (TDH de 4,1, 8,2 e 12,3 horas, e três taxas de aplicação superficial (TAS (21, 12 e 8m³/m².d. A associação dos reatores UASB+BAS possibilitou remoções de DQO total superiores a 90% para os BAS 1 e 3, e 85% para o BAS 2, sendo independente do TDH aplicado. A remoção de SS foi maior no BAS contendo anéis Pall, provavelmente devido ao maior índice de vazios desse material.The post-treatment of effluents from anaerobic reactors is normally a mandatory step to meet the emission standards. The results presented here show the feasibility of using a new configuration of biological aerated filter (BAF in the post-treatment of UASB reactors. The multi-stage BAF presents an anaerobic chamber (V=12.6L, followed by an aerobic chamber (V=30L and an anoxic chamber (V=26.4L, all in series (total V=70L. This study examined the removal of suspended solids (SS, COD and BOD5. Three multi-stage BAF filled with three different packing materials were used: lids and bottlenecks of PET bottles (165m²/m³, gravel n. 4 (50m²/m³ and Pall rings 1.5'' (135m²/m³. The reactors were operated with the values of hydraulic detention time (HDT of 4.1, 8.2 and 12.3 hours, and
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Making Sense of the Abstraction Hierarchy in the Power Plant Domain
DEFF Research Database (Denmark)
Lind, Morten
2003-01-01
The paper discusses the abstraction hierarchy proposed by Rasmussen [(1986) Information processing and human-machine interaction, North-Holland] for design of human-machine interfaces for supervisory control. The purpose of the abstraction hierarchy is to represent a work domain by multiple levels...... of means-end and part-whole abstractions. It is argued in the paper that the abstraction hierarchy suffers from both methodological and conceptual problems. A cluster of selected problems are analyzed and illustrated by concrete examples from the power plant domain. It is concluded that the semantics...... in the model-building process. It is also pointed out that attempts to clarify the semantics of the abstraction hierarchy will invariably reduce the range of work domains where it can be applied....
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Estimation of mean-reverting oil prices: a laboratory approach
International Nuclear Information System (INIS)
Bjerksund, P.; Stensland, G.
1993-12-01
Many economic decision support tools developed for the oil industry are based on the future oil price dynamics being represented by some specified stochastic process. To meet the demand for necessary data, much effort is allocated to parameter estimation based on historical oil price time series. The approach in this paper is to implement a complex future oil market model, and to condense the information from the model to parameter estimates for the future oil price. In particular, we use the Lensberg and Rasmussen stochastic dynamic oil market model to generate a large set of possible future oil price paths. Given the hypothesis that the future oil price is generated by a mean-reverting Ornstein-Uhlenbeck process, we obtain parameter estimates by a maximum likelihood procedure. We find a substantial degree of mean-reversion in the future oil price, which in some of our decision examples leads to an almost negligible value of flexibility. 12 refs., 2 figs., 3 tabs
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Centers for Disease Control (CDC) Podcasts
On January 22, 2016, MMWR first published a report on the possible association between Zika virus infection and microcephaly. This was the first of more than 60 MMWR reports on Zika virus. In this podcast, Dr. Sonja Rasmussen chats with Dr. Peggy Honein, co-lead for the Pregnancy and Birth Defects Task Force for CDC's Zika response, about the mosquito-borne flavivirus.
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International Nuclear Information System (INIS)
Ruckdeschel, W.
1980-01-01
The German nuclear power plants (here Grafenrheinfeld, Isar) dispose of large-scale provisions echeloned in depth against release of activity due to incidents. According to human judgement environmental risks can be excluded. The direct risk is explained in the Rasmussen-study and in the German Risk Study Nuclear Power Plants. The Inhaber-study represents an important contribution to the risk assessment. (DG) [de
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Tougher containment design goals
International Nuclear Information System (INIS)
O'Farrelly, C.
1978-01-01
Present day LWR containment design goals are reviewed, together with their potential failure modes. Rasmussen's estimates of failure probabilities are discussed and the concept of ''delayed failure'' is seen to be a valuable safety goal for hypothetical accidents. The paper investigates the inherent coremelt resistance capability of various containment designs and suggests improvements, with special emphasis on increasing the failure delay times. (author)
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Kom nyliberalismen til Danmark i 1982?
DEFF Research Database (Denmark)
Ydesen, Christian; Høberg, Per
2009-01-01
Med afsæt i statsminister Anders Fogh Rasmussens nytårstaler fra 2004 og 2007, hvor der tales om en konsekvent økonomisk linje fra 1982 og frem til i dag, rejser dette bidrag en diskussion af, hvorvidt og på hvilke præmisser startskuddet til det nuværende nyliberale regime i Danmark lød med lance...
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Lõpp naiste ja meeste palgavahele / Poul Nyrup Rasmussen, Marianne Mikko
Rasmussen, Poul Nyrup
2007-01-01
Euroopa sotsiaaldemokraadid alustavad võitlust meeste ja naiste vahel püsiva palgaerinevusega. Euroopa Sotsiaaldemokraatliku Partei esimehe ja Euroopa Sotsiaaldemokraatliku Partei naisühenduse juhatuse liikme sõnul juhitakse tähelepanu ebaõiglusele, andes 22. veebruarile erilise tähenduse. See on päev, kui naissoost töötajad alustavad tõsist palgateemalist dialoogi oma tööandjate ja kolleegidega
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Report on Contract W911NF-05-1-0339 (Clarkson University)
2012-11-30
2012 59.00 Josiah Jebaraj J. Muthuraj, Don H. Rasmussen, Ian I. Suni. Electrodeposition of CuGaSe[sub 2] from Thiocyanate-Containing Electrolytes...Roy. Kinetic aspects of Li intercalation in mechano-chemically processed cathode materials for lithium ion batteries: Electrochemical characterization...Dipankar Roy. Electrochemical features of ball-milled lithium manganate spinel for rapid-charge cathodes of lithium ion batteries, Journal of Solid State
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2012-10-15
filtration (Mustang Q membrane ; Pall). The final polishing column for c13C6 and c6D8 was a CHT, Type I 40-μm (Bio-Rad) column. The columnwas...monkey chow, primate treats, fruits, and vegetables throughout the course of the study. Animals were observed at least once daily to monitor overall...Coulter Act 10 (Beckman Coulter) on samples collected in EDTA plasma vacuette tubes (Greiner Bio-One). Blood was collected in 2-mL serum vacuette tubes
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Farmer, Michael L.
2005-01-01
Iran and the United States have faced each other across a deep divide ever since the Iranian Revolution of 1979 and the events of the American Embassy Hostage crisis. The absence of diplomatic relations between the two nations has led to a lack of communication which has resulted in difficulties crafting successful policies to build bridges between the two governments. The specter of Iran's quest for nuclear weapons casts a further pall on the troubled relations. Case studies of historical ex...
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Marshall, J.; Sauke, T.; Buehler, M.; Farrell, W.; Green, R.; Birchenough, A.
1999-09-01
A granular-materials experiment is being developed for a 2002 launch for Space Station deployment. The experiment is funded by NASA HQ and managed through NASA Lewis Research Center. The experiment will examine electrostatic aggregation of coarse granular materials with the goals of (a) obtaining proof for an electrostatic dipole model of grain interactions, and (b) obtaining knowledge about the way aggregation affects the behavior of natural particulate masses: (1) in unconfined dispersions (clouds such as nebulae, aeolian dust palls, volcanic plumes), (2) in semi-confined, self-loaded masses as in fluidized flows (pyroclastic surges, avalanches) and compacted regolith, or (3) in semi-confined non-loaded masses as in dust layers adhering to solar cells or space suits on Mars. The experiment addresses both planetary/astrophysical issues as well as practical concerns for human exploration of Mars or other solar system bodies. Additional information is contained in the original.
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International Nuclear Information System (INIS)
1978-01-01
This report contains several essays on the rational ways of assessing the hazards, and choosing, the future energy production systems. Theories of decision analysis are touched upon by a number of authors and the fault tree statistical method is described. The Rasmussen report (WASH-1400) and a few related papers are discussed. As an example of the risks of advanced technological systems, the air traffic safety is accounted for. (L.E.)
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Wave Induced Loads on the LEANCON Wave Energy Converter
DEFF Research Database (Denmark)
Frigaard, Peter; Kofoed, Jens Peter; Beserra, Eliab Ricarte
This report is a product of the co-operation agreement between Aalborg University and LEANCON (by Kurt Due Rasmussen) on the evaluation and development of the LEANCON wave energy converter (WEC). The work reported here has focused on evaluation of the wave induced loads on the device, based...... in the laboratory, all under the supervision of the personnel of the Wave Energy Research Group at Department of Civil Engineering, Aalborg University....
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Patient Workload Profile: National Naval Medical Center (NNMC), Bethesda, MD.
1980-06-01
AD-A09a 729 WESTEC SERVICES NC SAN DIEGOCA0S / PATIENT WORKLOAD PROFILE: NATIONAL NAVAL MEDICAL CENTER NNMC),- ETC(U) JUN 80 W T RASMUSSEN, H W...provides site workload data for the National Naval Medical Center (NNMC) within the following functional support areas: Patient Appointment...on managing medical and patient data, thereby offering the health care provider and administrator more powerful capabilities in dealing with and
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2001-01-01
Vabariigi presidendi Lennart Meri autasud Tallinna Pedagoogikaülikooli õppejõududele: Valgetähe III klass - Heldur Palli (ajaloolane, Demograafia Instituut), Valgetähe IV klass - Mati Heidmets (psühholoogia professor), Valdek Pall (keeleteadlane, emeriitprofessor), Jaan-Mati Punning (geoökoloogia professor), Valgetähe V klass - Toomas Liiv (eesti kirjanduse professor), Viivi Maanso (emakeeleõppejõud), Valgetähe medal - Hergi Karik (keemik, emeriitprofessor), Mare Lott (raamatuteadlane, emeriitprofessor), Evi Rannap (infoteadlane, emeriitprofessor), Eesti Punase Risti IV klass - Taimi Tulva (sotsiaaltöö professor)
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International Nuclear Information System (INIS)
Ning, L.; Feng, L.H.; Chi, L.Z.; Xia, C.Z.
2015-01-01
Salsola L. is a large genus of arid desert plants that are primarily distributed in the Junggar Basin, China. We analysed their ability to adapt to arid habitats by comparing differences in germination characteristics of the species and populations of Salsola affinis C. A. Mey, Salsola korshinskyi Drob., Salsola brachiata Pall. and Salsola nitraria Pall. We classified the 4 species into four types (A, B, C and D) according to seed wing and seed size, and the heteromorphic seeds were incubatedunder different temperature regimes (0/10 degree C, 5/15 degree C, 10/25 degree C and 20/35 degree C). The 4 species had the highest germination rates and germination potential at 0/1 C. Germination rates and potential decreased with increasing temperature. However, the change range of the germination rate among the four species was different. Type A and B seeds of S. affinis, S. nitraria and S. korshinskyi were dominant at all temperatures and decreased with increasing temperature. The germination rate of type C seeds was between that of type A, B and D seeds. D-type seeds had the lowest germination rate and the lowest germination potential under the four temperature regimes among the four species but the differences were not significant. The germination rates of the four types of S. brachiata seeds did not significantly change with temperature. These results suggest that Salsola spp. can germinate continuously from spring to autumn to adapt to moisture fluctuations in the desert. (author)
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"edo jal̀qkina üts̀varòkaetus ma vaelda ..." : [luuletused] / Andreas Kalkun
Kalkun, Andreas, 1977-
2002-01-01
Sisu: "edo jal̀qkina üts̀varòkaetus ma vaelda ..." ; "tsirguq ku kiviq no satassõ taivast aràlaq ..." ; "vahtsõq silmäq pitsitä pääluu sisse ..." ; "tõppõ tõmmat haigõst ma haarõt jal̀ki ..." ; "arsatas njago sisse aigopiteh ..." ; "rühkeq yks jumalat pallõlda jaloh ..." ; "mu süä om no süüdläne täǹtäseq kuvvõ ..." ; "halvaq haavaq häitsese veiga silmih. Eluloolisi andmeid autori kohta lk. 379
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Intracellular Signaling Defects Contribute to TH17 Dysregulation during HIV Infection
2014-05-16
review of biochemistry 62:543-85 353. Xu H, Wang X, Liu DX, Moroney-Rasmussen T, Lackner AA, Veazey RS. 2012. IL-17-producing innate lymphoid cells ...maximum, CD4+ cell counts (blue) decline sharply at first because of trapping in lymphoid tissues but then rise again to a moderately subnormal level...then disseminates to draining lymph nodes and other lymphoid tissues, where it infects CD4+ target cells (42; 206; 241). Dissemination coincides
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Digital Repository Service at National Institute of Oceanography (India)
Linshy, V.N.; Saraswat, R.; Kurtarkar, S.R.; Nigam, R.
the harmful effects reaching the higher organisms. Various chemical, physical, physiological as well as biological methods have been formulated and adopted to detect marine pollution. Conventional biological methods of pollution detection have included... reported as a major contaminant that can cause adverse effects on aquatic system (Rasmussen and Anderson, 2000; Adami et al., 2002; Fillipovic and Raspor, 2003). It is an industrially used substance with long lasting negative effects on human health...
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Born Global Sourcers – buying internationally right from the inception
DEFF Research Database (Denmark)
Rask, Morten; Servais, Per
time researchers has identified various types of INV’s and based on the empirical work by Rasmussen et al (2010) a particular type of international new venture is isolated. The Born Global sourcers which is firms who conducts international purchasing from or near their establishment but who only...... be a viable starting point for research into this type, but that this research could be supplemented by including the relations to domestic clients/partners....
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Security conference convenes in Munich / Ella Karapetyan
Karapetyan, Ella
2011-01-01
Eesti president osales Münchenis toimunud rahvusvahelisel julgeolekupoliitika konverentsil, kus räägiti ka strateegilist tuumarelvastust piiravast START lepingust, olukorrast araabia maades ja finantskriisi mõjust julgeolekule. Toomas Hendrik Ilves juhtis diskussiooni relvastuskontrollist. Konverentsil osalesid ka Robert Zoellick, Wolfgang Schaueble, George Soros, Karl-Theodor zu Guttenberg, William Hague, Hillary Clinton, Sergei Lavrov, David Cameron, Catherine Ashton, Ban ki-moon, Anders Fogh Rasmussen ja Angela Merkel. Müncheni julgeolekukonverents 04.02.2011 - 06.02.2011
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Early Mortality Experience in a Large Military Cohort and a Comparison of Mortality Data Sources
2010-05-24
population-based cohort study. Ann Epidemiol 2007, 17(7):525-532. 9. Wentworth DN, Neaton JD, Rasmussen WL: An evaluation of the Social Security...Health 1992, 82(8):1145-1447. 13. Calle EE, Terrell DD: Utility of the National Death Index for ascertainment of mortality among Cancer Prevention Study...Hynes DM: A primer and comparative review of major US mortality databases. Ann Epidemiol 2002, 12(7):462-468. 18. Sesso HD, Paffenbarger RS, Lee
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2016-06-26
COMP ARIS ON OF INTERNAL ADAPTATION OF FIXED RESTO RA TIO NS FABRICATED FROM FOUR DIFFERENT MATERIALS BY A THREE-AXIS MILL by Bryan Paul...MATERIALS BY A THREE-AXIS MILL is appropriately acknowledged and, beyond brief excerpts, is with the permission of the copyright owner. ~r2L~ Bryan Paul...RESTORATIONS FABRICATED FROM FOUR DIFFERENT MATERIALS BY A THREE-AXIS MILL LCDR Bryan Paul Rasmussen, DC USN Prosthodontics Dept., 2016 Directed by
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2009-10-14
Simpson, 1948; Lovelock et al., 1972; Andreae, 1990; Leck et al., 1990). Facchini et al. (2008a) have also shown that biogenic emissions are a...fastigiata, Dimethyl-2- carboxy-ethylsulphonium hydroxide and its salts, J. Chem. Soc., 3, 1591-1597. Charlson, R. J., Lovelock , J. E., Andreae...aerosols for pristine Arctic clouds, Tellus, 57B, 261-268. Lovelock , J. E., Maggs, R. J., and R. A. Rasmussen (1972). Atmospheric dimethyl sulfide and
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Harvest season, high polluted season in East China
International Nuclear Information System (INIS)
Huang Xin; Song Yu; Li Mengmeng; Li Jianfeng; Zhu Tong
2012-01-01
East China, a major agricultural zone with a dense population, suffers from severe air pollution during June, the agricultural harvest season, every year. Crop burning emits tremendous amounts of combustion products into the atmosphere, not only rapidly degrading the local air quality but also affecting the tropospheric chemistry, threatening public health and affecting climate change. Recently, in mid-June 2012, crop fires left a thick pall of haze over East China. We evaluated the PM 10 , PM 2.5 (particulates less than 10 and 2.5 μm in aerodynamic diameter) and BC (black carbon) emissions by analyzing detailed census data and moderate resolution imaging spectroradiometer (MODIS) remote sensing images and then simulated the consequent pollution using meteorological and dispersion models. The results show that the crop fires sweeping from the south to the north are responsible for the intensive air pollution during harvest season. It is necessary for scientists and governments to pay more attention to this issue. (letter)
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Directory of Open Access Journals (Sweden)
Hee-Jung Choi
Full Text Available In the present study, we investigated the role of Paeonia lactiflora Pall. extract on embryo implantation in vitro and in vivo. A polysaccharides depleted-water extract of P. lactiflora (PL-PP increased LIF expression in human endometrial Ishikawa cells at non-cytotoxic doses. PL-PP significantly increased the adhesion of the human trophectoderm-derived JAr spheroids to endometrial Ishikawa cells. PL-PP-induced LIF expression was decreased in the presence of a p38 kinase inhibitor SB203580 and an MEK/ERK inhibitor U0126. Furthermore, endometrial LIF knockdown by shRNA reduced the expression of integrins β3 and β5 and adhesion of JAr spheroids to Ishikawa cells. In vivo administration of PL-PP restored the implantation of mouse blastocysts in a mifepristone-induced implantation failure mice model. Our results demonstrate that PL-PP increases LIF expression via the p38 and MEK/ERK pathways and favors trophoblast adhesion to endometrial cells.
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A new subgenus of Heterotrigona from New Guinea (Hymenoptera: Apidae)
DEFF Research Database (Denmark)
Engel, Michael S.; Rasmussen, Claus
2017-01-01
A new subgenus is established within the Indomalayan stingless bee genus Heterotrigona Schwarz (Meliponini). Sahulotrigona Engel & Rasmussen, new subgenus, is distinguished from amongst other Heterotrigona, particularly the subgenus Platytrigona Moure, within which one of the two included species...... in the following new combinations: Heterotrigona (Platytrigona) flaviventris (Friese), H. (P.) hobbyi (Schwarz), H. (P.) keyensis (Friese), H. (P.) lamingtonia (Cockerell), H. (P.) planifrons (Smith), H. (Sundatrigona) lieftincki (Sakagami & Inoue), and H. (Su.) moorei (Schwarz). The stingless bees of Papuasia...
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Producing a local, organic diet gives a healthy, sustainable and more climate-friendly diet
DEFF Research Database (Denmark)
Mogensen, Lisbeth; Kristensen, Troels; Hermansen, John Erik
2011-01-01
In: Organic is life – Knowledge for tomorrow (Neuhoff, D., Halberg, N., Rasmussen. I., Hermansen, J., Ssekyewa, C., Sohn, S.M. eds.). Proceedings of the Third Scientific Conference of the International Society of Organic Agriculture Research (ISOFAR), held at the 17th IFOAM Organic World Congress...... – in Cooperation with the International Federation of Organic Agriculture Movements (IFOAM) and the Korean Organizing Committee (KOC). Namyangju, Korea, 28. Sep – 1. Oct. 2011. Volume 2, 68-71 (paper, oral)...
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1983-12-01
and Corps of Engineers response. C-21 APPUWIX C C-3 Letter Pg m. Cape Girardeau Chamber of Commerce , 27 December 1983. C-24 n. U.S. Department of the...of erosion. Sincerely, Jack F. Rasmussen, P.E. Chief, Planning D ivision APPENDIX C C-23 Cape Girardeau Chamber of Commerce EXECUTIVE OFFICE December...Girardeau Chamber of Commerce has received and studied the Water Resources and Investigation, Cape Girardeau - Jackson area dated December, 1983 and we
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Epithermal Neutron Activation Analysis of the Asian Herbal Plants
International Nuclear Information System (INIS)
Baljinnyam, N.; Frontasyeva, M. V.; Ostrovnaya, T. M.; Pavlov, S. S.; Jugder, B.; Norov, N.
2011-01-01
Asian medicinal herbs Chrysanthemum (Spiraea aquilegifolia Pall.) and Red Sandalwood (Pterocarpus Santalinus) are widely used in folk and Ayurvedic medicine for healing and preventing some diseases. The modern medical science has proved that the Chrysanthemum (Spiraea aquilegifolia Pall.) possesses the following functions: reducing blood press, dispelling cancer cell, coronary artery's expanding and bacteriostating and Red Sandalwood (Pterocarpus Santalinus) is recommended against headache, toothache, skin diseases, vomiting and sometimes it is taken for treatment of diabetes. Species of Chrysanthemums were collected in the north-eastern and central Mongolia, and the Red Sandalwood powder was imported from India. Samples of Chrysanthemums (branches, flowers and leaves)(0.5 g) and red sandalwood powder (0.5 g) were subjected to the multi-element instrumental neutron activation analysis using epithermal neutrons (ENAA) at the IBR-2 reactor, Frank Laboratory of Neutron Physics (FLNP) JINR, Dubna. A total of 41 elements (Na, Mg, Al, Cl, K, Ca, Sc, V, Cr, Mn, Fe, Co, Ni, Zn, As, Se, Br, Rb, Sr, Zr, Mo, Cd, Cs, Ba, La, Hf, Ta, W, Sb, Au, Hg, Ce, Nd, Sm, Eu, Tb, Dy, Yb, Th, U, Lu) were determined. For the first time such a large group of elements was determined in the herbal plants used in Mongolia. The quality control of the analytical results was provided by using certified reference material Bowen Cabbage. The results obtained are compared to the ''Reference plant? data (B. Markert, 1992) and interpreted in terms of excess of such elements as Se, Cr, Ca, Fe, Ni, Mo, and rare earth elements.
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Directory of Open Access Journals (Sweden)
VIEIRA, Fábio Lopes
2005-05-01
Full Text Available RESUMOCom base nas tabelas de insumo-produto do Brasil para 1992, 1995, 1999 e 2000, este trabalho destaca um panorama evolutivo dos setores econômicos brasileiros no período. Como corolário, o domínio das relações inter-setoriais na economia brasileira foi dos setores Metalurgia/Siderurgia e Química, corroborados pela tradição de Hirschman/Rasmussen e pelo conceito de campo de influência.ABSTRACTUsing input-output analysis this paper presents for 1992, 1995, 1999 and 2000 a comparative analysis of the Brazilian economics sections in the period. As result, it was verified that the domain of the inter-sector relationships in the Brazilian economy was of the sections Metallurgy of iron and steel and Chemistry, corroborated by the tradition of the influence field concept.RESUMENCon base en las tablas de insumo-producto de Brasil para 1992, 1995, 1999 y 2000, este trabajo destaca el panorama evolutivo de los sectores económicos brasileños en ese período. Como corolario, el dominio de las relaciones intersectoriales en la economía brasileña correspondió a los sectores Metalurgia/Siderurgia y Química, corroborados por la tradición de Hirschman/Rasmussen y por el concepto de campo de influencia.
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[Application of rafting K-wire technique for tibial plateau fractures].
Zhang, Xing-zhou; Yu, Wei-zhong; Li, Yun-feng; Liu, Yan-hui
2015-12-01
To summarize application of rafting K-wires technique for tibial plateau fractures. From January 2013 to January 2015,45 patients with tibial plateau fractures were treated by locking plate with rafting K-wires, including 33 males and 12 females with an average of 44.2 years old ranging from 22 to 56 years old. According to Schatzker classification, 6 cases were type II, 8 were type Ill, 4 were type IV, 4 were type V, and 5 were type VI. Allogeneic bone graft were performed for bone defects. All patients were fixed with two to five K-wires. Part of weight loading were encouraged at 3 months after operation,and full weight-loading were done at 5 months after operation. Postoperative complications were observed,and Rasmussen clinical and radiological assessment were used to evaluate clinical results. All Patients were followed up from 10 to 23 months with average of 14 months. According to Rasmussen clinical and radiological assessment, clinical scores 23.58 ± 6.33, radiological scores were 14.00 ± 6.33; and excellent and good rates were 82.2% and 77.8% respectively. Four patients occurred severe osteoporosis and collapse of articular surface; 5 patients occurred traumatic arthritis. Rafting K-wires technique with anatomized armor plate could effective fix and support platform collapse and joint bone fragments, increase support surface area and reduce postoperative reduction loss rate.
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Zulewska, J; Newbold, M; Barbano, D M
2009-04-01
Raw milk (2,710 kg) was separated at 4 degrees C, the skim milk was pasteurized (72 degrees C, 16 s), split into 3 batches, and microfiltered using pilot-scale ceramic uniform transmembrane pressure (UTP; Membralox model EP1940GL0.1microA, 0.1 microm alumina, Pall Corp., East Hills, NY), ceramic graded permeability (GP; Membralox model EP1940GL0.1microAGP1020, 0.1 microm alumina, Pall Corp.), and polymeric spiral-wound (SW; model FG7838-OS0x-S, 0.3 microm polyvinylidene fluoride, Parker-Hannifin, Process Advanced Filtration Division, Tell City, IN) membranes. There were differences in flux among ceramic UTP, ceramic GP, and polymeric SW microfiltration membranes (54.08, 71.79, and 16.21 kg/m2 per hour, respectively) when processing skim milk at 50 degrees C in a continuous bleed-and-feed 3x process. These differences in flux among the membranes would influence the amount of membrane surface area required to process a given volume of milk in a given time. Further work is needed to determine if these differences in flux are maintained over longer processing times. The true protein contents of the microfiltration permeates from UTP and GP membranes were higher than from SW membranes (0.57, 0.56, and 0.38%, respectively). Sodium-dodecyl-sulfate-PAGE gels for permeates revealed a higher casein proportion in GP and SW permeate than in UTP permeate, with the highest passage of casein through the GP membrane under the operational conditions used in this study. The slight cloudiness of the permeates produced using the GP and SW systems may have been due to the presence of a small amount of casein, which may present an obstacle in their use in applications when clarity is an important functional characteristic. More beta-lactoglobulin passed through the ceramic membranes than through the polymeric membrane. The efficiency of removal of serum proteins in a continuous bleed-and-feed 3x process at 50 degrees C was 64.40% for UTP, 61.04% for GP, and 38.62% for SW microfiltration
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A new species of Astragalus (Fabaceae from west coast of Baikal Lake (Irkutsk Oblast
Directory of Open Access Journals (Sweden)
N. V. Stepantsova
2015-05-01
Full Text Available A new species, Astragalus rytyensis Stepantsova (Fabaceae, growing on the west coast of the lake Baikal, is described. Morphological differences from related taxa – A. versicolor Pall., A. austrosibiricus Schischk., and A. inopinatus Boriss., are discussed and uncertain position of the new species in the system of the genus is emphasized which is intermediate between subg. Phaca (L. Bunge sect. Hemiphaca Bunge and subg. Cercidothrix Bunge sect. Onobrychium Bunge. Ecological and phonological features of A. rytyensis are reported and chromosome numbers of the new (2n = 6x = 48 and related species are counted.
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Plant operator performance evaluation based on cognitive process analysis experiment
International Nuclear Information System (INIS)
Ujita, H.; Fukuda, M.
1990-01-01
This paper reports on an experiment to clarify plant operators' cognitive processes that has been performed, to improve the man-machine interface which supports their diagnoses and decisions. The cognitive processes under abnormal conditions were evaluated by protocol analyses interviews, etc. in the experiment using a plant training simulator. A cognitive process model is represented by a stochastic network, based on Rasmussen's decision making model. Each node of the network corresponds to an element of the cognitive process, such as observation, interpretation, execution, etc. Some observations were obtained as follows, by comparison of Monte Carlo simulation results with the experiment results: A process to reconfirm the plant parameters after execution of a task and feedback paths from this process to the observation and the task definition of next task were observed. The feedback probability average and standard deviation should be determined for each incident type to explain correctly the individual differences in the cognitive processes. The tendency for the operator's cognitive level to change from skill-based to knowledge-based via rule-based behavior was observed during the feedback process
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DEFF Research Database (Denmark)
Hansen, M L; Gadsbøll, N; Rasmussen, S
2009-01-01
Abstract. Hansen ML, Gadsbøll N, Rasmussen S, Gislason GH, Folke F, Andersen SS, Schramm TK, Sørensen R, Fosbøl EL, Abildstrøm SZ, Madsen M, Poulsen HE, Køber L, Torp-Pedersen C (Gentofte University Hospital, Hellerup; Sygehus Nord, Køge; National Institute of Public Health; Rigshospitalet-Copenh...... thromboembolic events were observed amongst patients from low OAC use hospitals. Our study emphasizes the need for a continued vigilance on implementation of international AF management guidelines....
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Centers for Disease Control (CDC) Podcasts
2018-01-11
On January 22, 2016, MMWR first published a report on the possible association between Zika virus infection and microcephaly. This was the first of more than 60 MMWR reports on Zika virus. In this podcast, Dr. Sonja Rasmussen chats with Dr. Peggy Honein, co-lead for the Pregnancy and Birth Defects Task Force for CDCâs Zika response, about the mosquito-borne flavivirus. Created: 1/11/2018 by MMWR. Date Released: 1/11/2018.
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How to evaluate steam explosions in the light of recent knowledge - possibility, course and effect
International Nuclear Information System (INIS)
Mayinger, F.
Experimental and theoretical investigations performed in the last years and concerning the phenomenology and the effect of steam explosions allow a much more realistic estimation, whether and how the pressure vessel and the containment could be endangered by such an accident than this was possible at the time when the Rasmussen-study and the Deutsche Risikostudie - Phase A - were published. The status of knowledge and some simple physical deliberations with respect to the mechanical effect of a steam explosion are presented. (orig.) [de
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Hemorrhage Control for Major Traumatic Vascular Injuries
2017-10-01
TJ, Eastridge BJ, Gilani R, Chung KK, DeSantis SM, DuBose JJ , Tomasek TS, Fortuna GR, Sames VG, Todd SR, Podbielski JM, Wade CE, Holcomb JB and the...Eastridge BJ, Gilani R, Chung KK, DeSantis SM, DuBose JJ , Tomasek JS, Fortuna GR, Sams VG, Todd SR, Podbielski JM, Wade CE, Holcomb JB. Multicenter...Kisat M, Morrison JJ , Hashmi ZG, Efron DT, Rasmussen TE, Haider AH. Epidemiology and outcomes of non-compressible torso hemorrhage. J Surg Res. 2013;184
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Digital Repository Service at National Institute of Oceanography (India)
Yoshinari, T.; Altabet, M.A.; Naqvi, S.W.A.; Codispoti, L.; Jayakumar, D.A.; Kuhland, M.; Devol, A.
of the correlation between apparent oxygen utilization and N,O con- centration found in many portions of the ocean. However, such a correlation is not sufficient evi- dence to conclude that nitrification is the dominant source (Pierotti and Rasmussen, 1980...,O is also significantly affected by denitrification (Yoshinari and Koike, 1994). In the eastern tropical North Pa- cific, nitrate deficits (an estimate of the NO; con- verted to N, by denitrification) are relatively large in the water mass that contains...
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Numerical modeling of polar mesocyclones generation mechanisms
Sergeev, Dennis; Stepanenko, Victor
2013-04-01
parameters, lateral boundary conditions are varied in the typically observed range. The approach is fully nonlinear: we use a three-dimensional non-hydrostatic mesoscale model NH3D_MPI [1] coupled with one-dimensional water body model LAKE. A key method used in the present study is the analysis of eddy kinetic and available potential energy budgets. References 1. Mikushin, D.N., and Stepanenko, V.M., The implementation of regional atmospheric model numerical algorithms for CBEA-based clusters. Lecture Notes in Computer Science, Parallel Processing and Applied Mathematics, 2010, vol. 6067, p. 525-534. 2. Rasmussen, E., and Turner, J. (eds), Polar Lows: Mesoscale Weather Systems in the Polar Regions. Cambridge: Cambridge University Press, 2003, 612 pp. 3. Yanase, W., and Niino, H., Dependence of Polar Low Development on Baroclinicity and Physical Processes: An Idealized High-Resolution Experiment, J. Atmos. Sci., 2006, vol. 64, p. 3044-3067.
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Reply to Ira Rabin’s Comment on our paper Rasmussen et al.
Rasmussen, Kaare Lund; Tenorio, Anna Lluveras; Bonaduce, Ilaria; Colombini, Maria Perla; Birolo, Leila; Galano, Eugenio; Amoresano, Angela; Doudna, Greg; Bond, Andrew D.; Palleschi, Vincenzo; Lorenzetti, Giulia; Legnaioli, Stefano; van der Plicht, Johannes; Gunneweg, Jan
2012-01-01
In the Comment by Dr. I. Rabin from Bundesanstalt für Materialforschung und -prüfung in Berlin are stated many conjectures and apparent guesses contradicting several of our interpretations. Most of Rabin’s ‘guesses’ and interpretations are unwarranted. Below we rebut some of the misinterpretations
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Objectives and present status of the German risk evaluation study
International Nuclear Information System (INIS)
Birkhofer, A.; Koeberlein, K.; Heuser, F.W.
1977-01-01
For the German risk evaluation study, analogous to the Rasmussen report (WASH--1400), embarked upon in June 1976, the Kernkraftwerk Biblis B serves as the plant of reference. The first interim results are available for various sub-headings of the study. The main finding seems to be the decisive importance of the containment in limiting the accident consequences even in those cases where, on account of postulated failure of safety systems, the melt down of the reactor core is to be expected. (orig./HP) [de
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Disruptive event uncertainties in a perturbation approach to nuclear waste repository risk analysis
Energy Technology Data Exchange (ETDEWEB)
Harvey, T.F.
1980-09-01
A methodology is developed for incorporating a full range of the principal forecasting uncertainties into a risk analysis of a nuclear waste repository. The result of this methodology is a set of risk curves similar to those used by Rasmussen in WASH-1400. The set of curves is partially derived from a perturbation approach to analyze potential disruptive event sequences. Such a scheme could be useful in truncating the number of disruptive event scenarios and providing guidance to those establishing data-base development priorities.
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Mosbrucker, Adam; Spicer, Kurt R.; Christianson, Tami; Uhrich, Mark A.
2015-01-01
Fluvial sediment, a vital surface water resource, is hazardous in excess. Suspended sediment, the most prevalent source of impairment of river systems, can adversely affect flood control, navigation, fisheries and aquatic ecosystems, recreation, and water supply (e.g., Rasmussen et al., 2009; Qu, 2014). Monitoring programs typically focus on suspended-sediment concentration (SSC) and discharge (SSQ). These time-series data are used to study changes to basin hydrology, geomorphology, and ecology caused by disturbances. The U.S. Geological Survey (USGS) has traditionally used physical sediment sample-based methods (Edwards and Glysson, 1999; Nolan et al., 2005; Gray et al., 2008) to compute SSC and SSQ from continuous streamflow data using a sediment transport-curve (e.g., Walling, 1977) or hydrologic interpretation (Porterfield, 1972). Accuracy of these data is typically constrained by the resources required to collect and analyze intermittent physical samples. Quantifying SSC using continuous instream turbidity is rapidly becoming common practice among sediment monitoring programs. Estimations of SSC and SSQ are modeled from linear regression analysis of concurrent turbidity and physical samples. Sediment-surrogate technologies such as turbidity promise near real-time information, increased accuracy, and reduced cost compared to traditional physical sample-based methods (Walling, 1977; Uhrich and Bragg, 2003; Gray and Gartner, 2009; Rasmussen et al., 2009; Landers et al., 2012; Landers and Sturm, 2013; Uhrich et al., 2014). Statistical comparisons among SSQ computation methods show that turbidity-SSC regression models can have much less uncertainty than streamflow-based sediment transport-curves or hydrologic interpretation (Walling, 1977; Lewis, 1996; Glysson et al., 2001; Lee et al., 2008). However, computation of SSC and SSQ records from continuous instream turbidity data is not without challenges; some of these include environmental fouling, calibration, and
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Directory of Open Access Journals (Sweden)
Jihua Wang
2012-09-01
Full Text Available Halimodendron halodendron has been used as forage in northwestern China for a long time. Its young leaves and flowers are edible and favored by indigenous people. In this study, eleven phenolic compounds were bioassay-guided and isolated from the aerial parts of H. halodendron for the first time. They were identified by means of physicochemical and spectrometric analysis as quercetin (1, 3,5,7,8,4'-pentahydroxy-3'-methoxy flavone (2, 3-O-methylquercetin (3, 3,3'-di-O-methylquercetin (4, 3,3'-di-O-methylquercetin-7-O-β-D-glucopyranoside (5, isorhamentin-3-O-β-D-rutinoside (6, 8-O-methylretusin (7, 8-O-methylretusin-7-O-β-D-glucopyranoside (8, salicylic acid (9, p-hydroxybenzoic acid (ferulic acid (10, and 4-hydroxy-3-methoxy cinnamic acid (11. They were sorted as flavonols (1–6, soflavones (7 and 8, and phenolic acids (9–11. Among the compounds, flanools 1–4 revealed a strong antibacterial activity with minimum inhibitory concentration (MIC values of 50–150 μg/mL, and median inhibitory concentration (IC50 values of 26.8–125.1 μg/mL. The two isoflavones (7 and 8 showed moderate inhibitory activity on the test bacteria. Three phenolic acids (9, 10 and 11 showed strong antibacterial activity with IC50 values of 28.1–149.7 μg/mL. Antifungal activities of the compounds were similar to their antibacterial activities. All these phenolic compounds showed significant antimicrobial activity with a broad spectrum as well as antioxidant activity based on 1,1-diphenyl-2-picrylhydrazyl (DPPH radical scavenging and β-carotene-linoleic acid bleaching assays. In general, the flavonol aglycones with relatively low polarity exhibited stronger activities than the glycosides. The results suggest the potential of this plant as a source of functional food ingredients and provide support data for its utilization as forage as well.
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Flexicurity in the Current Economic and Social Context
Directory of Open Access Journals (Sweden)
Georgeta Modiga
2015-05-01
Full Text Available The flexicurity concept - an abbreviation between flexibility and security - appeared in the early 90s, being used for the first time by the Danish Prime Minister Poul Nyrum Rasmussen. The concept refers to a social state model that promotes a pro-active policy in the labour domain and the access to employment. Flexicurity can be defined as a strategy integrated by the simultaneous consolidation of flexibility and security on the labour market. According to the definition given by the European Commission, which establishes the guidelines and “paths” typical for the Member States in order to develop their own strategies in the field, flexicurity is an integrated strategy of simultaneous strengthening of flexibility and security on labour market. This concept arose as a result of socio-economic changes registered in the last decades in Europe: globalization and European integration, development of new technologies, the demographic aging of European society, the segmented development of labour markets.
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Integration of strategy experiential learning in e-module of electronic records management
Directory of Open Access Journals (Sweden)
S. Sutirman
2018-01-01
Full Text Available This study aims to determine the effectiveness of e-module of electronic records management integrated with experiential learning strategies to improve student achievement in the domain of cognitive, psychomotor, and affective. This study is a research and development. Model research and development used is Web-Based Instructional Design (WBID developed by Davidson-Shivers and Rasmussen. The steps of research and development carried out by analysis, evaluation planning, concurrent design, implementation, and a summative evaluation. The approach used in this study consisted of qualitative and quantitative approaches. Collecting data used the Delphi technique, observation, documentation studies and tests. Research data analysis used qualitative analysis and quantitative analysis. Testing the effectiveness of the product used a quasi-experimental research design pretest-posttest non-equivalent control group. The results showed that the e-module of electronic records management integrated with experiential learning strategies can improve student achievement in the domain of cognitive, psychomotor, and affective.
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Donovan, Sarah-Louise; Salmon, Paul M; Lenné, Michael G; Horberry, Tim
2017-10-01
Safety leadership is an important factor in supporting safety in high-risk industries. This article contends that applying systems-thinking methods to examine safety leadership can support improved learning from incidents. A case study analysis was undertaken of a large-scale mining landslide incident in which no injuries or fatalities were incurred. A multi-method approach was adopted, in which the Critical Decision Method, Rasmussen's Risk Management Framework and Accimap method were applied to examine the safety leadership decisions and actions which enabled the safe outcome. The approach enabled Rasmussen's predictions regarding safety and performance to be examined in the safety leadership context, with findings demonstrating the distribution of safety leadership across leader and system levels, and the presence of vertical integration as key to supporting the successful safety outcome. In doing so, the findings also demonstrate the usefulness of applying systems-thinking methods to examine and learn from incidents in terms of what 'went right'. The implications, including future research directions, are discussed. Practitioner Summary: This paper presents a case study analysis, in which systems-thinking methods are applied to the examination of safety leadership decisions and actions during a large-scale mining landslide incident. The findings establish safety leadership as a systems phenomenon, and furthermore, demonstrate the usefulness of applying systems-thinking methods to learn from incidents in terms of what 'went right'. Implications, including future research directions, are discussed.
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[Treatment of Schatzker IV tibial plateau fractures with arthroscopy combined with MIPPO technique].
Li, Jian-Wen; Ye, Feng; Bi, Da-Wei; Zheng, Xiao-Dong; Chen, Jian-Liang
2018-02-25
To discusses the clinical effects of arthroscopy combined with minimally invasive percutaneous plate osteosynthesis(MIPPO) technology in treating Schatzker IV tibial plateau fractures. From January 2012 to January 2016, 19 patients with Schatzker type IV tibial plateau fractures were treated with arthroscopy combined with minimally invasive technique including 12 males and 7 females with an average age of 46.5 years old ranging from 19 to 78 years old. Patients were suffering knee pain, swelling, flexion and extension limited, and other symptoms preoperative. Patients were followed up and assessed by Rasmussen knee function score. No infection, traumatic arthritis, and knee joint valgus occurred after operation. Nineteen cases were followed up for 12 to 24 months with an average of 18.6 months. Fracture healing time was 3 to 5 months with an average of 3.8 months. The knee pain and limited mobility improved significantly. The range of autonomic movement of joints was from 90 to 136 degrees. According to Rasmussen functional score criteria, the total score was 27.00±2.49, the result was excellent in 16 cases, good in 2 cases, fair in 1 case. Arthroscopic treatment for Schatzker type IV tibial plateau fractures combined with MIPPO can simultaneously treat internal structural injuries such as meniscus and other knee joints, with less trauma, fewer complications, and faster joint function recovery, but we must strictly grasp surgical indications and avoid expanding injuries. Copyright© 2018 by the China Journal of Orthopaedics and Traumatology Press.
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Giannotti, S; Giovannelli, D; Dell'Osso, G; Bottai, V; Bugelli, G; Celli, F; Citarelli, C; Guido, G
2016-04-01
The tibial plateau fractures involve one of the main weight bearing joints of the human body. The goals of surgical treatment are anatomical reduction, articular surface reconstruction and high primary stability. The aim of this study was to evaluate the clinical and functional outcomes after internal plate fixation of this kind of fractures. From January 2009 to December 2012, we treated 75 cases of tibial plateau fracture with angular stable plates. We used Rasmussen Score and the Knee Society Score for the clinical and functional evaluation. Twenty-five cases that underwent hardware removal had arthroscopic and CT evaluation of the joint. No complications occurred. The clinical and functional evaluation, performed by the KSS and Rasmussen Score, highlighted the high percentage of good-to-excellent results (over 90 %). In every case, the range of motion was good with flexion >90°. Arthroscopy showed the presence of chondral damage in 100 % of patients. In all the cases, we found that X-ray images seem better than the CT images. Angular stable plates allow to obtain a good primary stability, permitting an early joint recovery with an excellent range of motion. Avoiding to perform a knee arthrotomy at the time of fracture reduction could prove to be an advantage in terms of functional recovery. The meniscus on the injured bone should be preserved in order to maintain good function of the joint. X-ray images remain the gold standard in checking the progression of post-traumatic osteoarthritis.
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International Nuclear Information System (INIS)
Patterson, W.
1999-01-01
Changes in our electricity systems provoked by natural gas power generation technology are paving the way for large-scale renewables use in the future. Natural gas and gas turbines are now such a cheap and easy option for electricity generation that they appear to cast a pall over renewables. The market share of gas-fired generation continues expanding inexorably. Its cost continues to fall, setting renewables an ever more demanding competitive target. Nevertheless, paradoxical though this may sound, natural gas is actually the natural ally of renewables. Despite the fierce competitive challenge it represents, natural gas may even be the most important single factor shaping a bright future for renewables. (author)
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Seed protein variations of Salicornia L. and allied taxa in Turkey.
Yaprak, A E; Yurdakulol, E
2007-06-01
Electrophoretic seed protein patterns of a number of accessions of Salicornia europaea L. sl., S. prostrata Palas, S. fragilis P.W. Ball and Tutin, Sarcocornia fruticosa (L.) A. J. Scott, Sarcocornia perennis (Miller.) A. J. Scott, Arthrocnemum glaucum (Del.) Ung.-Sternb., Microcnemum coralloides (Loscos and Pardo) subsp. anatolicum Wagenitz and Halocnemum strobilaceum (Pall.) Bieb. were electrophoretically analysed on SDS-PAGE. In total 48 different bands were identified. The obtained data have been treated numerically using the cluster analysis method of unweighted pair group (UPGMA). Finally it was determined that all species separated according to seed protein profiles. And the cladogram obtained studied taxa have been given.
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Directory of Open Access Journals (Sweden)
Chen H
2018-04-01
Full Text Available Hengwen Chen,* Yan Dong,* Xuanhui He, Jun Li, Jie Wang Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China *These authors contributed equally to this work Background: Paeoniflorin (PF is the active component of Paeonia lactiflora Pall. or Paeonia veitchii Lynch. This study was, therefore, aimed to evaluate the improvement and mechanism of the PF on ventricular remodeling in rats with acute myocardial infarction (AMI. Materials and methods: In this study, AMI model was established by ligating the anterior descending coronary artery in Wistar rats. After 4 weeks gavage of PF, the apparent signs and the left ventricle weight index of Wistar rats were observed. The left ventricular ejection fraction (LVEF was evaluated by Doppler ultrasonography. Changes in cardiac morphology were observed by pathologic examination, and apoptosis was observed by the terminal deoxynucleotidyl transferase dUTP nick end labeling assay. In addition, enzyme-linked immunosorbent assay was used to detect the expression of tumor necrosis factor-α (TNF-α, interleukin-6 (IL-6 interleukin-10 (IL-10 and brain natriuretic peptide (BNP. Immunohistochemistry and Western blot method were applied to detect Caspase-3 and Caspase-9. Results: Compared with the model control, the survival conditions of rats in all treatment groups were generally improved after PF treatment. LVEF was significantly increased, and both left ventricular end-diastolic inner diameter and left ventricular end-systolic inner diameter were significantly reduced. Moreover, pathologic examination showed that the myocardium degeneration of the rats treated with PF was decreased, including neater arrangement, more complete myofilament, more uniform gap and less interstitial collagen fibers. Furthermore, the mitochondrial structure of cardiomyocytes was significantly improved. The ultrastructure was clear, and the arrangement of myofilament was more regular. Also, the expression of
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Teamarbejde og samspillet mellem medarbejdere og organisation
DEFF Research Database (Denmark)
Jeppesen, Hans Jeppe; Jønsson, Thomas
2008-01-01
Gennem det seneste årti har brug af teams som en måde at organisere arbejdet på været i hastig fremmarch. Det er baggrunden for forskningsprojektet ”Team-organiseringens betydning for participation og organisatoriske relationer”, der er et multiple case-studie af seks organisationers brug af...... teamwork. Bag projektet står professor Hans Jeppe Jeppesen, cand.psych. og ph.d. Thomas Rasmussen samt adjunkt Thomas Jønsson. I denne klumme gives en forskningsbaseret introduktion til teamarbejdet og dets betydning for samspillet mellem medarbejdere og organisation. Med udgangspunkt i egen forskning...
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Nuclear power stations and their environmental hazards
International Nuclear Information System (INIS)
Jansen, P.
1975-01-01
Starting from a consideration of the energy demand up to the year 2000, the author points out the necessity of nuclear power plant operation for electricity generation and discusses the possible danger to human populations. An assessment of the emission rate of radionuclides in nuclear power plant operation and the possible health hazards to the total population is based on a survey of the U.S. EPA of February 1972. The discussion of the accident risk is based on the results of Rasmussen's study of reactor safety. (ORU/AK) [de
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Nuclear energy and risk - experts meeting in November 1977 in Munich
Energy Technology Data Exchange (ETDEWEB)
Danzmann, H J
1978-02-01
As nuclear energy in public discussion is assessed not only by its benefit for the national economy, but above all by its risk, the interest in the subject was demonstrated by experts and public alike. The central point of the meeting was the German reactor safety study, apostrophized as 'Birkmussen Report', as in this report - under the leadership of A. Birkhofer - the applicability of the results of the American reactor safety study WASH-1400, the 'Rasmussen Report' (the final version of which appeared two years ago) on German conditions is investigated.
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DEFF Research Database (Denmark)
Rasmussen, Mikkel Vedby
If the military were a business, would you buy shares? Over recent years, Western armed forces, particularly the US, have been costing more yet achieving less. At the same time, austerity measures are reducing defence budgets. This book uses defence data to examine the workings of modern Western...... militaries and explore what kind of strategies can overcome this gap between input and output. Instead of focusing on military strategy, Mikkel Vedby Rasmussen seeks to draw on the ideas of business strategy to assess alternative business cases - reforming military HR to combat instability in the 'Global...
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What is the purpose of risk studies
International Nuclear Information System (INIS)
Birkhofer, A.
1986-01-01
Over the past few years, more or less comprehensive risk analyses have been carried out for numerous nuclear power plants, especially in the USA. The first risk studies conducted, especially the Rasmussen Study and the 'German Risk Study,' investigated sequences of accidents up to their environmental impacts. Risk studies today are focused mostly on assessments of technical safety, which is why they are extended only as far as the determination of core meltdown frequencies or radionuclide releases. Studies of this type are also called probabilistic safety analyses. (orig.) [de
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International Nuclear Information System (INIS)
Pollitt, C.
1980-01-01
The subject is discussed under the headings: megarisks - the case for their existence; megarisks - are they acceptable; identifying and estimating nuclear risks (the development of nuclear power; the changing character of the nuclear debate; hazard identification; probability estimation; alternative views of Rasmussen); evaluating nuclear outcomes (the Windscale enquiry; balancing risks; aversion; cost-benefit risk; summary; evaluation - a postscript [examples of differing accounts of an incident]); other megarisks (genetic manipulation); nuclear politics (the political characteristics of nuclear power; the distribution of costs and benefits; decision procedures; policy); Faustian bargains. (U,K,)
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Street Cries and the urban refrain
DEFF Research Database (Denmark)
Kreutzfeldt, Jacob
2012-01-01
Rasmussen have investigated Danish street cries as respectably a musical and a spatial phenomenon. Such studies – from each their perspectives – can be said to explore the aesthetics of urban environments, since street calls are specifically developed and heard in the context of the city. Investigating...... the different methods employed in the two studies and presenting Deleuze and Guattaris theory about the refrain as a framework for further studies in the field, this article seeks to outline a fertile area of study for sound studies: the investigation of everyday refrains and the environmental relations...
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How do we know that we all know?
DEFF Research Database (Denmark)
Rasmussen, Gitte
EMCA studies assume that actions through which members of society grasp the world are a) indexical and designed with reference to how they will be recognized and described, and thus with respect to the specifics of settings and co-participants; in sum they are viewed as morally chosen methods...... ‘grasping the world’ can be viewed as knowledge - by whom? References: Deppermann, A., Ed. (2013). Conversation analytic studies of multimodal interaction. Journal of Pragmatics. Special issue. Amsterdam, Elsevier. Garfinkel, H. (1967). Studies in Ethnomethodology. Cambridge, Polity Press. Rasmussen, G., S...
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The impact of WASH-1400 on reactor safety evaluation
International Nuclear Information System (INIS)
Tanguy, P.Y.
1976-01-01
Trends in reactor safety evaluation in France following the publication of WASH-1400 (the Rasmussen Report) are presented. What is called 'the meteorite case' is first schematically presented as follows: WASH-1400 shows nuclear risk equivalent to meteorite risk and reasonable corrections cannot make many orders of magnitude, consequently present safety rules are adequate. The very impact of WASH-1400 on safety approach is then discussed as for: assistance to deterministic safety analysis, introduction of probabilistic safety criteria, acceptable level of risk, and the use of results in research and reactor operating experience
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Evolution of the authoritarian 'atom state'
International Nuclear Information System (INIS)
Anon.
1979-01-01
Robert Jungk's book 'The Atom State' forms the basis for this article, which begins with a general discussion and criticism of such government sponsored reports as the Rasmussen report. The utilisation by the nuclear industry of modern PR methods is also criticised. Specifically, Bruno Kreisky and the Austrian Minister of the Economy, Herta Firnberg, are accused of attempting, through a secret project, to mislead the public and exercise unethical influence. It is maintained that the existence of a nuclear industry will necessitate control measures which lead to a totalitarian regime. (JIW)
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Antidepressant-like effect of peony glycosides in mice.
Mao, Qing-Qiu; Ip, Siu-Po; Tsai, Sam-Hip; Che, Chun-Tao
2008-09-26
The root part of Paeonia lactiflora Pall. (Ranunculaceae), known as peony, is often used in Chinese herbal formulae for the treatment of depression-like disorders. Previous studies in our laboratory have shown that an ethanol extract of peony produced antidepressive effects in mouse models of depression. It is well known that peony contains glycosides such as paeoniflorin and albiflorin, yet it remains unclear whether the total glycosides of peony (TGP) are effective. The present study aims to evaluate the antidepressant-like effects of TGP. The antidepressant-like effects of TGP was determined by using animal models of depression including forced swim and tail suspension tests. The acting mechanism was explored by determining the effect of TGP on the activities of monoamine oxidases. Intragastric administration of TGP at 80 and 160 mg/kg for seven days caused a significant reduction of immobility time in both forced swim and tail suspension tests, yet TGP did not stimulate locomotor activity in the open-field test. In addition, TGP treatment antagonized reserpine-induced ptosis and inhibited the activities of monoamine oxidases in mouse cerebrum. These results suggest that the antidepressive effects of TGP are mediated, at least in part, by the inhibition of monoamine oxidases.
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Conformal partition functions of critical percolation from D 3 thermodynamic Bethe Ansatz equations
Morin-Duchesne, Alexi; Klümper, Andreas; Pearce, Paul A.
2017-08-01
Using the planar Temperley-Lieb algebra, critical bond percolation on the square lattice can be reformulated as a loop model. In this form, it is incorporated as {{ L}}{{ M}}(2, 3) in the Yang-Baxter integrable family of logarithmic minimal models {{ L}}{{ M}}( p, p\\prime) . We consider this model of percolation in the presence of boundaries and with periodic boundary conditions. Inspired by Kuniba, Sakai and Suzuki, we rewrite the recently obtained infinite Y-system of functional equations. In this way, we obtain nonlinear integral equations in the form of a closed finite set of TBA equations described by a D 3 Dynkin diagram. Following the methods of Klümper and Pearce, we solve the TBA equations for the conformal finite-size corrections. For the ground states of the standard modules on the strip, these agree with the known central charge c = 0 and conformal weights Δ1, s for \\renewcommand≥≥slant} s\\in {{ Z}≥slant 1} with Δr, s=\\big((3r-2s){\\hspace{0pt}}^2-1\\big)/24 . For the periodic case, the finite-size corrections agree with the conformal weights Δ0, s , Δ1, s with \\renewcommand{≥{≥slant} s\\in\\frac{1}{2}{{ Z}≥slant 0} . These are obtained analytically using Rogers dilogarithm identities. We incorporate all finite excitations by formulating empirical selection rules for the patterns of zeros of all the eigenvalues of the standard modules. We thus obtain the conformal partition functions on the cylinder and the modular invariant partition function (MIPF) on the torus. By applying q-binomial and q-Narayana identities, it is shown that our refined finitized characters on the strip agree with those of Pearce, Rasmussen and Zuber. For percolation on the torus, the MIPF is a non-diagonal sesquilinear form in affine u(1) characters given by the u(1) partition function Z2, 3(q)=Z2, 3{Circ}(q) . The u(1) operator content is {{ N}}Δ, \\barΔ=1 for Δ=\\barΔ=-\\frac{1}{24}, \\frac{35}{24} and {{ N}}Δ, \\barΔ=2 for
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The pollen complex from postglacial sediments of the Laptev Sea as a bioindicator
Naidina, O. D.
2014-05-01
The first results of comparison of palynological analysis (pollen of terrestrial plants), SEM analysis of pollen morphology, and radiocarbon age dating (AMS14C) of sediments of the eastern shelf of the Laptev Sea show that the diverse taxonomic composition of pollen spectra provides an integrated idea of the vegetation and climate of the region over 11.2 calendar kiloyears. It is found that phases of the tree and shrub vegetation development (maxima of pollen of Betula sect. Nanae and Pinus s/g Haploxylon) correspond to the warm epochs in the Holocene. It is obvious that birch phytocoenoses first settled in the southern tundra subzone with increasing temperature, and then coniferous communities of forest tundra. An occurrence of pollen of shrubby birches (Nanae) suggests compliance of permafrost landscapes with cold climate conditions, i.e., with an annual average temperature of -2°C and amount of precipitation of less than 500 mm. Owing to a progressive increase in summer temperatures, dwarf cedar and pine communities advanced toward the seashore. The SEM analysis results show that a significant proportion of regional coniferous pollen belongs to representatives of Pinus pumila (Pall.) and P. sylvestris L. In addition, the SEM study of the exine of Pinus sylvestris L. and P. pumila (Pall.) Regel pollen grains confirmed polymorphism in coniferous pollen. According to the inverse relationship between climate and vegetation, frequent climate fluctuations that are typical of progressive and differential postglacial transgression were revealed. An increase in arboreal pollen transfer onto the shelf later than 9.1 cal. ka coincides with the time of forest boundary migration to the north due to the warming of the Earth's climate. At that time, the tundra vegetation was replaced by forest-tundra vegetation, the maximum stage of sea transgression began, and there appeared a trend of increasing temperature and moisture.
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Tao, Xingguang; Chen, Nong; Pan, Fugen; Cheng, Biao
2017-10-01
The aim of this study was to evaluate the clinical efficacy of external fixation, delayed open reduction, and internal fixation in treating tibial plateau fracture with dislocation.Clinical data of 34 patients diagnosed with tibial plateau fracture complicated with dislocation between January 2009 and May 2015 were retrospectively analyzed. Fifteen patients in group A underwent early calcaneus traction combined with open reduction and internal fixation and 19 in group B received early external fixation combined with delayed open reduction and internal fixation. Operation time, postoperative complication, bone healing time, knee joint range of motion, initial weight-bearing time, Rasmussen tibial plateau score, and knee function score (HSS) were statistically compared between 2 groups.The mean follow-up time was 18.6 months (range: 5-24 months). The mean operation time in group A was 96 minutes, significantly longer than 71 minutes in group B (P .05). In group A, initial weight-bearing time in group A was (14.0 ± 3.6) weeks, significantly differing from (12.9 ± 2.8) weeks in group B (P 0.05). Rasmussen tibial plateau score in group A was slightly lower than that in group B (P > .05). The excellent rate of knee joint function in group A was 80% and 84.21% in group B (P > .05).External fixation combined with delayed open reduction and internal fixation is a safer and more efficacious therapy of tibial plateau fracture complicated with dislocation compared with early calcaneus traction and open reduction and internal fixation.
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Implementing Environmental Management Accounting: Status and Challenges
DEFF Research Database (Denmark)
Cost Accounting - and its Interaction with Eco-Efficiency Performance Measurement and Indicators; Stefan Schaltegger and Marcus Wagner. 4. Environmental Accounting Dimensions: Pros and Cons of Trajectory Convergence and Increased Efficiency; Pontus Cerin and Staffan Laestadius. 5. Process and Content......Table of contents Preface. 1. Environmental Management Accounting: Innovation or Managerial Fad?; Pall Rikhardsson, Martin Bennett, Jan Jaap Bouma and Stefan Schaltegger. Section 1 Progress. 2. Challenges for Environmental Management Accounting; Roger L. Burritt 3. Current Trends in Environmental......: Visualizing the Policy Challenges of Environmental Management Accounting; Dick Osborn. Section 2 Exploring EMA implementation issues. 6. Environmental Performance and the Quality of Corporate Environmental Reports: The Role of Environmental Management Accounting; Marcus Wagner. 7. Environmental Risk...
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Floxner, Mattias
2014-01-01
Ruinkvarteret Tyresö gymnasium har gjort sitt som funktion av en skola. Byggnaden har gjort sitt för att stå pall för människan och naturen. Nu har den börjat förfalla. Fuktskador, otäta fönster och allmänt slitage har gjort att Tyresö kommun har besätmt sig för att renovera eller bygga om skolan till bostäder. Ett nytt bostadskvarter i ett naturlandskap där bebygelsen ligger som öar utan att förhålla sig till varandra med endast naturen som sammanbinder dem. Där det byggda är symbol för männ...
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DEFF Research Database (Denmark)
Skjøt, Rikke L. V.; Oettinger, Thomas; Rosenkrands, Ida
2000-01-01
. The molecules were characterized, mapped in a two-dimensional electrophoresis reference map of short-term culture filtrate, and compared with another recently identified low-mass protein, CFP10 (F. X. Berthet, P, B. Rasmussen, I. Rosenkrands, P. Andersen, and B. Gicquel. Microbiology 144:3195-3203, 1998......), and the well-described ESAT-6 antigen. Genetic analyses demonstrated that TB10.4 as well as CFP10 belongs to the ESAT-6 family of low-mass proteins, whereas TB7.3 is a low-molecular-mass protein outside this family. The proteins were expressed in Escherichia coli, and their immunogenicity was tested...
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DEFF Research Database (Denmark)
Marling, Gitte
2014-01-01
This article presents analyses of the ‘Nørrebro Bike Route’ as an ‘urban bikescape’ consisting of a mixture of lanes and coupled urban places and small parks. It is a place to sit, to play and to relax, but at the same time it also a place for mobility. It is a social-technical assemblage (Urry 2...... (scale, rhythm, content) & aesthetics developed? (Thies- Evensen 1992, Venturi 1972, Rasmussen 2003, Thrift 2004, Merleau-Ponty 2009, Pallismaa 2005, Pink 2009)? Finally the article addresses the travelling ideas of ‘new urban bikescapes’ and Nordic urban space design....
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Bayesian estimation of core-melt probability
International Nuclear Information System (INIS)
Lewis, H.W.
1984-01-01
A very simple application of the canonical Bayesian algorithm is made to the problem of estimation of the probability of core melt in a commercial power reactor. An approximation to the results of the Rasmussen study on reactor safety is used as the prior distribution, and the observation that there has been no core melt yet is used as the single experiment. The result is a substantial decrease in the mean probability of core melt--factors of 2 to 4 for reasonable choices of parameters. The purpose is to illustrate the procedure, not to argue for the decrease
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Preventing microbial growth on pall-rings when upgrading biogas using absorption with water wash
Energy Technology Data Exchange (ETDEWEB)
Haakansson, Anna
2006-07-15
For produced biogas to be usable as vehicle fuel it has to be upgraded to a higher energy content. This is accomplished by elevation of the methane concentration through removal of carbon dioxide. Absorption with water wash is the most common upgrading method used in Sweden today. The upgrading technique is based on the fact that carbon dioxide is more soluble in water than methane. Upgrading plants that utilises this method have problems with microbial growth in the system. This growth eventually leads to a stop in operation due to the gradually drop in upgrading capacity. The aim of this thesis were to evaluate the possibility to through some kind of water treatment maintain an acceptable level of growth or altogether prevent it in order to maintain an acceptable process capacity and thereby avoid the need to clean. Through collection of literature the implementation possibilities were evaluated with regard to efficiency, economic sustainability and if there would be a release of any harmful substances. In order to prevent the microbial growth in the columns the treatment should either focus on removing microorganisms or limit the accessible nutrients. For the single pass system it is concluded that the treatment should reduce the biofilm formation and be employed in an intermittent way. Among the evaluated treatments focusing on the reduction of microorganisms the addition of peracetic acid seems to be the most promising one. For the regenerating system the treatment method could focus on either one. As for the single pass system peracetic acid could be added to reduce the amount of microorganism. To reduce the amount of organic matter an advanced oxidation process could be deployed with the advantage that it also could remove the microorganisms.
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Atlantic Warm Pool Trigger for the Younger Dryas Climate Event
Abdul, N. A.; Mortlock, R. A.; Wright, J. D.; Fairbanks, R. G.; Teneva, L. T.
2011-12-01
There is growing evidence that variability in the size and heat content of the tropical Atlantic Warm Pool impacts circum-North Atlantic climate via the Atlantic Multi-decadal Oscillation mode (Wang et al., 2008). The Atlantic Warm Pool spans the Gulf of Mexico, Caribbean Sea and the western tropical North Atlantic. Barbados is located near the center of the tropical Atlantic Warm Pool and coupled ocean models suggest that Barbados remains near the center of the tropical Atlantic Warm Pool under varying wind stress simulations. Measurements of the oxygen isotope paleothermometer in Acropora palmata coral species recovered from cores offshore Barbados, show a 3oC monotonic decrease in sea surface temperature from 13106 ± 83 to 12744 ± 61 years before present (errors given as 2 sigma). This interval corresponds to a sea level rise from 71.4 meters to 67.1 meters below present levels at Barbados. The 3oC temperature decrease is captured in eight A. palmata specimens that are in stratigraphic sequence, 230Th/234U dated, and analyzed for oxygen isotopes. All measurements are replicated. We are confident that this is the warm pool equivalent of the Younger Dryas climate event. The initiation of this temperature drop in the Atlantic Warm Pool predates the Younger Dryas start in Greenland ice cores, reported to start at 12896 ± 138 years (relative to AD 2000) (Rasmussen et al., 2006), while few other Younger Dryas climate records are dated with similar accuracy to make the comparison. Rasmussen, S.O., Andersen, K.K., Svensson, A.M., Steffensen, J.P., Vinther, B.M., Clausen, H.B., Siggaard-Andersen, M.L., Johnsen, S.J., Larsen, L.B., Dahl-Jensen, D., Bigler, M., Röthlisberger, R., Fischer, H., Goto-Azuma, K., Hansson, M.E., and Ruth, U., 2006, A new Greenland ice core chronology for the last glacial termination: J. Geophys. Res., v. 111, p. D06102. Wang, C., Lee, S.-K., and Enfield, D.B., 2008, Atlantic Warm Pool acting as a link between Atlantic Multidecadal
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A conceptual framework for intelligent real-time information processing
Schudy, Robert
1987-01-01
By combining artificial intelligence concepts with the human information processing model of Rasmussen, a conceptual framework was developed for real time artificial intelligence systems which provides a foundation for system organization, control and validation. The approach is based on the description of system processing terms of an abstraction hierarchy of states of knowledge. The states of knowledge are organized along one dimension which corresponds to the extent to which the concepts are expressed in terms of the system inouts or in terms of the system response. Thus organized, the useful states form a generally triangular shape with the sensors and effectors forming the lower two vertices and the full evaluated set of courses of action the apex. Within the triangle boundaries are numerous processing paths which shortcut the detailed processing, by connecting incomplete levels of analysis to partially defined responses. Shortcuts at different levels of abstraction include reflexes, sensory motor control, rule based behavior, and satisficing. This approach was used in the design of a real time tactical decision aiding system, and in defining an intelligent aiding system for transport pilots.
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Human reliability assessment on the basis of operating experience
International Nuclear Information System (INIS)
Straeter, O.
1997-01-01
For development of methodology, available models for qualitative assessment of human errors (e.g. by Swain, Hacker, Rasmussen) and a variety of known systematic approaches for quantitiative assessment of inadequate human action (e.g. THERP, ASEP, HCR, SLIM) were taken as a basis to establish a job specification, which in turn was used for developing a method for acquisition, characterisation and evaluation of errors. This method encompasses the two processes of event analysis and event evaluation: The first step comprises analysis of events by analysis of information describing the conditions and scenarios of relevance to the inadequate human action examined. In addition to the description of process sequences, information is taken into account on possible conditions that may bring about failure. As an assessment of human reliability requires manifold approaches for evaluation, a connectionistic procedure was developed for evaluation of the compilation of events based on a debate about various approaches from the domain of artificial intelligence (AI). This procedure yields both qualitative and quantitative information through a homogenous approach. (orig./GL) [de
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SUPPLEMENTAL ON-LINE MATERIAL, INFLUENCE OF pH ON PLUTONIUM DESORPTION/SOLUBILIZATION FROM SEDIMENT
International Nuclear Information System (INIS)
Kaplan, D
2006-01-01
The oxidation state distribution of Pu in each sample for each reaction time was measured using a combined ultrafiltration and solvent extraction technique (1-4). First the oxidation state distribution of aqueous Pu is measured. Then the total system (solid and aqueous phase combined) Pu oxidation state distribution is measured by lowering the pH to leach Pu from the solid phase. For each reaction time, a 2.5-mL aliquot of the aqueous phase was removed and passed through a 12-nm filter (Microsep 30K MWCO Centrifugal Device; Pall Corporation, East Hills, NY). An aliquot of the filtrate was removed to determine the aqueous phase Pu concentration, and oxidation state distribution in the remaining filtrate was measured using the parallel solvent extraction technique discussed
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Maslova, N. V.; Elizaryeva, O. A.; Galikeeva, G. M.; Tyutyunova, N. M.
2018-01-01
This paper presents the results of investigations introducing eight rare species of the genus Oxytropis DC. from the flora of the Republic of Bashkortostan into the city of Ufa. Seven species are characterized as promising ornamental plants. According to the integrated evaluation scale of introduction effectiveness based on seven indices, two species were considered as very promising (O. spicata (Pall.) O. et B. Fedtsch., O. knjazevii Vasjukov), five species as promising (O. approximata Less., O. baschkirensis Knjasev, O. hippolyti Boriss., O. gmelinii Boriss., O. kungurensis Knjasev) and one species as non-promising (O. sordida (Willd.) Pers.). The ornamental quality assessment of rare species of the genus Oxytropis based on ten indices showed that these species can be used to create ornamental compositions in the landscape design style.
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Dust Storm Hits Canary Islands
2002-01-01
A thick pall of sand and dust blew out from the Sahara Desert over the Atlantic Ocean yesterday (January 6, 2002), engulfing the Canary Islands in what has become one of the worst sand storms ever recorded there. In this scene, notice how the dust appears particularly thick in the downwind wake of Tenerife, the largest of the Canary Islands. Perhaps the turbulence generated by the air currents flowing past the island's volcanic peaks is churning the dust back up into the atmosphere, rather than allowing it to settle toward the surface. This true-color image was captured by the Moderate-resolution Imaging Spectroradiometer (MODIS), flying aboard NASA's Terra satellite, on January 7, 2002. Image courtesy Jacques Descloitres, MODIS Land Rapid Response Team at NASA GSFC
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Gross, J-B; Gavanier, B; Belleville, R; Coudane, H; Mainard, D
2017-10-01
Proximal tibia fractures make up 1% of all fractures in adults. The fractures classified as Schatzker V and VI fractures can compromise knee structure and function. They are challenging to treat and often have complications. While plate fixation is the gold standard, the resulting infection rate has led us to favor external hybrid fixation. The aims of this study were to assess the radiographic and functional outcomes along with the complication rate when using this method and to compare them to historical plate fixation data. This was a retrospective study of 40 patients. The complications, quality of reduction, IKS, Lysholm and Rasmussen functional scores at the latest follow-up and factors affecting the functional outcome were evaluated. These parameters were compared to published results from plate fixation studies. The deep infection rate was 2.5%. The union rate was 80%. Satisfactory reduction was obtained in 70% of cases; however, 52% of patients had malunion. The mean IKS score was 73.74, the mean Rasmussen score was 22.85 and the mean Lysholm score was 75.53. Age, reduction at latest follow-up, mechanical axis and anteroposterior laxity had a significant effect on the functional outcome. Despite the malunion rate being higher than other studies, the functional outcomes were nearly identical based on the variables measured. There are several advantages associated with using a hybrid external fixator: shorter operative time, less bleeding, shorter hospital stays and lower infection rate. Hybrid external fixation is a reliable fracture fixation method that leads to satisfactory functional outcomes, while reducing the infection rate and allowing arthroplasty to be performed in the future if needed. Copyright © 2017 Elsevier Masson SAS. All rights reserved.
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Kee, Dohyung; Jun, Gyuchan Thomas; Waterson, Patrick; Haslam, Roger
2017-03-01
The South Korea Sewol ferry accident in April 2014 claimed the lives of over 300 passengers and led to criminal charges of 399 personnel concerned including imprisonment of 154 of them as of Oct 2014. Blame and punishment culture can be prevalent in a more hierarchical society like South Korea as shown in the aftermath of this disaster. This study aims to analyse the South Korea ferry accident using Rasmussen's risk management framework and the associated AcciMap technique and to propose recommendations drawn from an AcciMap-based focus group with systems safety experts. The data for the accident analysis were collected mainly from an interim investigation report by the Board of Audit and Inspection of Korea and major South Korean and foreign newspapers. The analysis showed that the accident was attributed to many contributing factors arising from front-line operators, management, regulators and government. It also showed how the multiple factors including economic, social and political pressures and individual workload contributed to the accident and how they affected each other. This AcciMap was presented to 27 safety researchers and experts at 'the legacy of Jens Rasmussen' symposium adjunct to ODAM2014. Their recommendations were captured through a focus group. The four main recommendations include forgive (no blame and punishment on individuals), analyse (socio-technical system-based), learn (from why things do not go wrong) and change (bottom-up safety culture and safety system management). The findings offer important insights into how this type of accident should be understood, analysed and the subsequent response. Copyright © 2016 Elsevier Ltd. All rights reserved.
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[Treatment of complex tibial plateau fractures with bilateral locking plate and bone graft].
Yan, Ying-Jie; Cheng, Zhan-Wei; Feng, Kai; Yan, Shao-Hua
2012-07-01
To explore the effective methods for the treatment of complex tibial plateau fractures. From May 2008 to April 2011, 28 patients with complex tibial plateau fractures were treated indirect reduction techniques, bilateral locking plate fixation combined with autologous bone grafts. There were 21 males and 7 females, with an average age of 43 years ranging from 21 to 65. There were 11 cases in Schatzker type V, 17 in VI. The effect was evaluated by Rasmussen standard on clinical and radiological. All patients were followed-up for 7 to 36 months (averaged of 21.5 months). Healing time of fracture was from 3 to 8 months (averaged 5.5 months). The results of Rasmussen scores in clinical was 4.50 +/- 1.32 in pain, 4.32 +/- 1.63 in walking ability, 4.07 +/- 1.34 in knee activity, 4.78 +/- 1.27 in stability of the knee, 4.85 +/- 1.12 in stretch knee; the results in radiation was 5.07 +/- 0.92 in articular surface collapse, 5.00 +/- 0.98 in platform widened, 5.14 +/- 0.85 in knee external varus. The effect result was excellent in 8 cases, good in 15, fair in 3 and poor in 2. The key for the treatment of complex tibial plateau fractures was to fully assess the damage as much as possible to protect the soft tissue, select the appropriate timing of surgery and surgical incision, application of indirect reduction techniques, limited incision and effective internal fixation to restore joint surface smooth and good limb alignment, early exercise, in order to achieve maximum recovery of joint function.
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DEFF Research Database (Denmark)
Rasmussen, Mikkel Vedby
If the military were a business, would you buy shares? Over recent years, Western armed forces, particularly the US, have been costing more yet achieving less. At the same time, austerity measures are reducing defence budgets. This book uses defence data to examine the workings of modern Western...... militaries and explore what kind of strategies can overcome this gap between input and output. Instead of focusing on military strategy, Mikkel Vedby Rasmussen seeks to draw on the ideas of business strategy to assess alternative business cases - reforming military HR to combat instability in the 'Global...... to fit within a nation's overall national security system without ever-increasing budgets....
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Directory of Open Access Journals (Sweden)
S. Pati
2014-01-01
Full Text Available The pathogenesis of disease progression in drug-refractory epilepsy is poorly understood. We report the case of a young woman with a four-year history of epilepsy that progressed rapidly as evidenced by the development of progressive focal cortical atrophy. She underwent biopsy that showed perinatal ischemia and a prominent inflammatory response, including T-cell infiltration and microglial activation. There was no consensus reached on the final diagnosis although the hypothesis of dual pathology (adult variant of Rasmussen's encephalitis and perinatal stroke was considered. The possible role of inflammation in the progression of epilepsy caused by a “static” lesion (perinatal stroke is discussed.
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Something important is missing from PRA
International Nuclear Information System (INIS)
Ward, D.A.
1991-01-01
This paper provides some views on priorities and directions for the future or risk management. There are some problems with the priorities and directions that now seem dominant. Norm Rasmussen of MIT and the late Saul Levine, who was then with the U.S. Atomic Energy Commission (AEC) (the NRC's predecessor), and their colleagues deserve much credit for the invention of the art of Probabilistic Risk Assessment. Certainly the elements of risk analysis were well known and used, at least implicitly, in much of engineering and technology. But, WASH-1400, The Reactor Safety Study issued in 1975, put these elements together in a comprehensive and courageously rational way
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Fernández-López de Pablo, Javier; Jones, Samantha E.; Burjachs, Francesc
2018-03-01
The period spanning the Late Glacial and the Early Holocene (≈19-8.2 ka) witnessed a dramatic sequence of climate and palaeoenvironmental changes (Rasmussen et al., 2014). Interestingly, some of the most significant transformations ever documented in human Prehistory took place during this period such as the intensification of hunter-gatherer economic systems, the domestication process of wild plants and animals, and the spread of farming across Eurasia. Understanding the role of climate and environmental dynamics on long-term cultural and economic trajectories, as well as specific human responses to episodes of rapid climate change, still remains as one of the main challenges of archaeological research (Kintigh et al., 2014).
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Social mening og viden på sociale video sites
DEFF Research Database (Denmark)
Rasmussen, Tove Arendt
2011-01-01
. De sociale medier som Facebook, YouTube o.l. er blevet prototype for det dialogiske aspekt, der egentlig ligger indbygget fra starten i de digitale netværksmedier. Modtageren, læseren, seeren og tilhøreren deltager i den medierede kommunikation med kommentar, dialog eller egne produkter. Brugeren er...... også producent og distributør adf viden i de sociale mediers brugerfællesskaber. Brugeren er ikke kun ’user’, men ’produser’ (sammentrækning af user og producer), skriver den amerikanske medieforsker Axel Bruns, som både Tove Arendt Rasmussen og hans Jørn Nielsen citerer i deres artikler”....
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Energy Technology Data Exchange (ETDEWEB)
Chassany, J [Commissariat a l' Energie Atomique, Centre de Production de Plutonium, Marcoule (France). Centre d' Etudes Nucleaires; Parigi, H [Institut de Mecanique des Fluides de Marseille, 13 (France); Salaun-Penquer, G [Centre National de la Recherche Scientifique (CNRS), 75 - Paris (France)
1961-07-01
The baffle placed at the top of a chimney determines the shape of the smoke pall for low exit-velocities. The G. 1 type baffle was studied taking into account the characteristics of its collar: totally hollow - partially hollow - solid; on a ribbed chimney or on a plain chimney. The Pu type baffle was also tested. The search for a new type of baffle was limited to variants of the blade - type baffle: - a porous envelope device; - a cone - shaped device and - a deflector of the cupel type. Only the blade-type baffle was rejected, efficient solutions are proposed using the other types or their combinations. (authors) [French] Le deflecteur place au sommet d'une cheminee conditionne l'allure du panache pour les rejets a faible vitesse de sortie. Le deflecteur type Gl a ete etudie en tenant compte de son embase: totalement evidee - partiellement evidee - pleine; sur une cheminee striee et sur une cheminee lisse. Le deflecteur type Pu a ete egalement teste. La recherche d'un nouveau type de deflecteur a porte sur les deflecteurs a aubage: - un dispositif a enveloppe poreuse; - un dispositif en ogive et - le deflecteur en coupelle. Seul le deflecteur a aubage a ete rejete, des solutions efficaces sont proposees avec les autres types ou leur combinaison. (auteurs)
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International Nuclear Information System (INIS)
Yoshida, Kazuo; Yokobayashi, Masao; Tanabe, Fumiya; Kawase, Katumi.
1996-01-01
A prototype version of a computer simulation system named JACOS (JAeri COgnitive Simulation system) has been developed at JAERI (Japan Atomic Energy Research Institute) to simulate the man-machine system behavior in which both the cognitive behavior of a human operator and the plant behavior affect each other. The objectives of this system development is to provide man-machine system analysts with detailed information on the cognitive process of an operator and the plant behavior affected by operator's actions in accidental situations of an NPP (nuclear power plant). The simulation system consists of an operator model and a plant model which are coupled dynamically. The operator model simulates an operator's cognitive behavior in accidental situations based on the decision ladder model of Rasmussen, and is implemented using the AI-techniques of the distributed cooperative inference method with the so-called blackboard architecture. Rule-based behavior is simulated using knowledge representation with If-Then type of rules. Knowledge-based behavior is simulated using knowledge representation with MFM (Multilevel Flow Modeling) and qualitative reasoning method. Cognitive characteristics of attentional narrowing, limitation of short-term memory, and knowledge recalling from long-term memory are also modeled. The plant model of a 3-loop PWR is also developed using a best estimate thermal-hydraulic analysis code RELAP5/MOD2. Some simulations of incidents were performed to verify the human model. It was found that AI-techniques used in the human model are suitable to simulate the operator's cognitive behavior in an NPP accident. The models of cognitive characteristics were investigated in the effects on simulated results of cognitive behaviors. (author)
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DEFF Research Database (Denmark)
Gormsen, Lise Kirstine; Søndergaard, Sara; Hoffmann, Tine
Work-in- progress Roundtable: Title: What ethical problems are out there? – a study of medical students’ reflexive writing about ethical dilemmas in the clinic. Authors: Lise Gormsen, MD, MHH, PhD., Institute of Clinical Medicine, Aarhus University, Denmark Jane Ege Møller, MA, PhD., Center...... Kristina Øgendahl Beeck, Medical student, Aarhus University, Denmark Corresponding and presenting author: Lise Gormsen, MD, MHH, Ph.D, Institute of Clinical Medicine, Aarhus University, Incuba/Skejby, building 2 Palle Juul-Jensens Boulevard 82, 8200 Aarhus N Denmark Phone: +45 23981599 Email: lise...... reflect themselves. Furthermore the material is ‘ negatively biased’ - the students write about the unsolved dilemmas. Conclusion: Reflective texts can be seen as data material that contains valuable knowledge, both concerning modes of reflection AND what types of ethical dilemmas that is a part...
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JACOS: AI-based simulation system for man-machine system behavior in NPP
International Nuclear Information System (INIS)
Yoshida, Kazuo; Yokobayashi, Masao; Tanabe, Fumiya; Komiya, Akitoshi
2001-08-01
A prototype of a computer simulation system named JACOS (JAERI COgnitive Simulation system) has been developed at JAERI (Japan Atomic Energy Research Institute) to simulate the man-machine system behavior in which both the cognitive behavior of a human operator and the plant behavior affect each other. The objectives of this system development is to provide man-machine system analysts with detailed information on the cognitive process of an operator and the plant behavior affected by operator's actions in accidental situations of a nuclear power plant. The simulation system consists of an operator model and a plant model which are coupled dynamically. The operator model simulates an operator's cognitive behavior in accidental situations based on the decision ladder model of Rasmussen, and is implemented using the AI-techniques of the distributed cooperative inference method with the so-called blackboard architecture. Rule-based behavior is simulated using knowledge representation with If-Then type of rules. Knowledge-based behavior is simulated using knowledge representation with MFM (Multilevel Flow Modeling) and qualitative reasoning method. Cognitive characteristics of attentional narrowing, limitation of short-term memory, and knowledge recalling from long-term memory are also taken into account. The plant model of a 3-loop PWR is also developed using a best estimate thermal-hydraulic analysis code RELAP5/MOD2. This report is prepared as User's Manual for JACOS. The first chapter of this report describes both operator and plant models in detail. The second chapter includes instructive descriptions for program installation, building of a knowledge base for operator model, execution of simulation and analysis of simulation results. The examples of simulation with JACOS are shown in the third chapter. (author)
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International Nuclear Information System (INIS)
Lin, Chiuhsiang Joe; Shiang, Wei-Jung; Chuang, Chun-Yu; Liou, Jin-Liang
2014-01-01
Highlights: • Operator behaviors were analyzed according to Rasmussen's SRK classification. • Different job positions connote different abilities to perform the job successfully. • Rule-based behavior comprised the main behavior patterns of the operating crew. - Abstract: For the past years, a number of researches have focused on operators’ behaviors and workloads in advanced main control rooms (MCRs) in either the procedure-domain or knowledge-domain and in either workload-increased or workload-decreased conditions. Different job positions connote different responsibilities and abilities that are required to perform the job successfully. However, it may be inappropriate to apply a dichotomy in these issues. In this study, we clarified these controversial points through the analysis of the time, frequency, and workload of the behaviors based on Rasmussen's skill–rule–knowledge classification (SRK framework) according to the supervisor operator (SRO), reactor operator (RO), and assistant reactor operator (ARO). The results showed that, for the SRO, rule- and knowledge-based behaviors occurred more often than skill-based behavior in terms of time and frequency, and knowledge-based behavior was the main source of workload. For the RO, no significant differences were found among the three behavior types in terms of frequency and workload, but more time was spent on rule-based behaviors than on skill- and knowledge-based behaviors. The ARO spent more time performing skill-based behaviors than rule- and knowledge-based behaviors, but in terms of frequency and workload, rule-based behavior was the predominant type. Operators’ behaviors contribute to a plant's defense-in-depth approach to safety and serve a vital function in ensuring its safe operation. Research on behavioral taxonomies of advanced MCRs has many significant benefits in both scientific-theoretical and applied practical fields
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Energy Technology Data Exchange (ETDEWEB)
Lin, Chiuhsiang Joe, E-mail: cjoelin@mail.ntust.edu.tw [Department of Industrial Management, National Taiwan University of Science and Technology, 43 Keelung Road, Section 4, Taipei 10607, Taiwan, ROC (China); Shiang, Wei-Jung, E-mail: wjs001@cycu.edu.tw [Department of Industrial Engineering, Chung-Yuan Christian University, 200, Chung Pei Rd., Chung-Li 32023, Taiwan, ROC (China); Chuang, Chun-Yu, E-mail: chunyu@iner.gov.tw [Department of Industrial Engineering, Chung-Yuan Christian University, 200, Chung Pei Rd., Chung-Li 32023, Taiwan, ROC (China); Institute of Nuclear Energy Research, 1000, Wunhua Rd., Jiaan Village, Longtan Township, Taoyuan 32546, Taiwan, ROC (China); Liou, Jin-Liang, E-mail: u683437@taipower.com.tw [Taiwan Power Company, 20F, 242, Roosevelt Rd., Sec. 3, Taipei 10016, Taiwan, ROC (China)
2014-04-01
Highlights: • Operator behaviors were analyzed according to Rasmussen's SRK classification. • Different job positions connote different abilities to perform the job successfully. • Rule-based behavior comprised the main behavior patterns of the operating crew. - Abstract: For the past years, a number of researches have focused on operators’ behaviors and workloads in advanced main control rooms (MCRs) in either the procedure-domain or knowledge-domain and in either workload-increased or workload-decreased conditions. Different job positions connote different responsibilities and abilities that are required to perform the job successfully. However, it may be inappropriate to apply a dichotomy in these issues. In this study, we clarified these controversial points through the analysis of the time, frequency, and workload of the behaviors based on Rasmussen's skill–rule–knowledge classification (SRK framework) according to the supervisor operator (SRO), reactor operator (RO), and assistant reactor operator (ARO). The results showed that, for the SRO, rule- and knowledge-based behaviors occurred more often than skill-based behavior in terms of time and frequency, and knowledge-based behavior was the main source of workload. For the RO, no significant differences were found among the three behavior types in terms of frequency and workload, but more time was spent on rule-based behaviors than on skill- and knowledge-based behaviors. The ARO spent more time performing skill-based behaviors than rule- and knowledge-based behaviors, but in terms of frequency and workload, rule-based behavior was the predominant type. Operators’ behaviors contribute to a plant's defense-in-depth approach to safety and serve a vital function in ensuring its safe operation. Research on behavioral taxonomies of advanced MCRs has many significant benefits in both scientific-theoretical and applied practical fields.
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Directory of Open Access Journals (Sweden)
Bouchain Galicia, Rafael C.
2009-01-01
Full Text Available RESUMEN Se presenta un análisis de los eslabonamientos industriales y la clasificación de industrias clave para 34 sectores de la economía mexicana utilizando la matriz de insumo producto de 2003 publicada por INEGI en Abril de 2008. Los cálculos se realizan para las dos tablas de insumo-producto referentes a la economía interna, que no considera la industria maquiladora de exportación, y a la economía total que incluye a la industria maquiladora. Los resultados muestran los encadenamientos interindustriales Hirschman-Rasmussen en sus dos versiones: eslabonamientos hacia atrás (índices de dispersión y una versión de los eslabonamientos hacia adelante (índices de sensibilidad. Esta clasificación nos permite verificar el grado de integración de las industrias al interior y exterior de la economía, mostrando un fuerte grado de composición externa de los insumos intermedios de las industrias de maquila.ABSTRACT This work presents an analysis of the industrial linkages and the classification of key industries for 34 sectors in the Mexican economy by using the 2003 input output matrix published by INEGI on April, 2008. The calculations are made for the two input-output tables concerning to domestic economy (without consider the bonded assembly plant importing industry and for the total economy which includes the bonded assembly plant industry. The results shows the Hirschman-Rasmussen interindustrial linkages in their two versions: backwards linkages (indices de dipersionand forward linkages (indices de sensibilidad. This classification allow us to verify the degree of integration of the industries that are inside and outside the economy, showing a strong degree of external composition from the bonded assembly plants middle insumos.
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Approximate simulation of Hawkes processes
DEFF Research Database (Denmark)
Møller, Jesper; Rasmussen, Jakob Gulddahl
2006-01-01
Hawkes processes are important in point process theory and its applications, and simulation of such processes are often needed for various statistical purposes. This article concerns a simulation algorithm for unmarked and marked Hawkes processes, exploiting that the process can be constructed...... as a Poisson cluster process. The algorithm suffers from edge effects but is much faster than the perfect simulation algorithm introduced in our previous work Møller and Rasmussen (2004). We derive various useful measures for the error committed when using the algorithm, and we discuss various empirical...... results for the algorithm compared with perfect simulations. Extensions of the algorithm and the results to more general types of marked point processes are also discussed....
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Certified Basic Life Support Instructors Assess Cardiopulmonary Resuscitation Skills Poorly
DEFF Research Database (Denmark)
Hansen, Camilla; Rasmussen, Stinne E; Kristensen, Mette Amalie
2016-01-01
Introduction: High-quality cardiopulmonary resuscitation (CPR) improves survival from cardiac arrest. During basic life support (BLS) training, instructors assess CPR skills to enhance learning outcome. Emergency department staff and senior residents have been shown to assess chest compression...... quality poorly. Currently no studies have evaluated CPR assessment among certified BLS instructors. The aim of this study was to investigate certified BLS instructors’ assessment of chest compressions and rescue breathing.Methods: Data were collected at BLS courses for medical students at Aarhus...... of CPR skills may be beneficial to ensure high-quality learning outcome.Author Disclosures: C. Hansen: None. S.E. Rasmussen: None. M.A. Nebsbjerg: None. M. Stærk: None. B. Løfgren: None....
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Global health intervention from North to South: (Academic) preparation of students
DEFF Research Database (Denmark)
Singla, Rashmi; Rasmussen, Louise Mubanda
2018-01-01
psychiatry/ psychology (Fernando), culture-centered health communication (Dutta) and medical anthropology (Farmer, Nguyen & Lock). The course is framed around a critical conceptualization of globalisation covering spatial and ideological dimensions (Fassin). Today’s practice of global health interventions......Global health intervention from North to South: (Academic) preparation of students By Rashmi Singla & Louise Mubanda Rasmussen, Roskilde University, Denmark This chapter discusses how to conduct before- intervention preparation of students based on a pioneer course collaboration between...... the subjects Health Promotion and International Development Studies at Roskilde University. The focus is on agents of intervention from the Global North with Global South targets. The theoretical framework of the course includes, among others approaches from cultural psychological (Valsiner), critical...
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DEFF Research Database (Denmark)
Joergensen, L.E.; Gunnarsdottir, K.A.; Lanng, C.
2008-01-01
The purpose of this study was to investigate the prognostic influence of multifocality in breast cancer patients. In a cohort of 7196 patients there were 945 patients with multifocality. We found no prognostic influence of multifocality on overall survival when controlling for known prognostic......, Gunnarsdottir KA, Rasmussen BB, Moeller S, Lanng C. The prognostic influence of multifocality in breast cancer patients. Breast 2004;13:188-193]....... factors. We found a small but significant influence on disease-free survival (HR=1.16 [1.03-1.31]) and a strong correlation between multifocality and known prognostic factors. This was in accordance with an earlier study done on a smaller population and in a different period of time [Pedersen L...
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Methane emissions from natural wetlands
Energy Technology Data Exchange (ETDEWEB)
Meyer, J.L. [Georgia Univ., Athens, GA (United States); Burke, R.A. Jr. [Environmental Protection Agency, Athens, GA (United States). Environmental Research Lab.
1993-09-01
Analyses of air trapped in polar ice cores in conjunction with recent atmospheric measurements, indicate that the atmospheric methane concentration increased by about 250% during the past two or three hundred years (Rasmussen and Khalil, 1984). Because methane is a potent ``greenhouse`` gas, the increasing concentrations are expected to contribute to global warning (Dickinson and Cicerone, 1986). The timing of the methane increase suggests that it is related to the rapid growth of the human population and associated industrialization and agricultural development. The specific causes of the atmospheric methane concentration increase are not well known, but may relate to either increases in methane sources, decreases in the strengths of the sinks, or both.
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International Nuclear Information System (INIS)
Knuefer; Lindauer
1980-01-01
Besides that at spectacular events a combination of component failure and human error is often found. Especially the Rasmussen-Report and the German Risk Assessment Study show for pressurised water reactors that human error must not be underestimated. Although operator errors as a form of human error can never be eliminated entirely, they can be minimized and their effects kept within acceptable limits if a thorough training of personnel is combined with an adequate design of the plant against accidents. Contrary to the investigation of engineering errors, the investigation of human errors has so far been carried out with relatively small budgets. Intensified investigations in this field appear to be a worthwhile effort. (orig.)
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Research on operation support system for nuclear power plants
International Nuclear Information System (INIS)
Wakabayashi, Jiro
1989-01-01
Nuclear power plants are the typical, complex, large scale engineering system, and at the time of accidents, there is the possibility to extend disasters to wide range beyond borders, therefore, it is the feature that the requirement for their reliability and safety is much severe as compared with other engineering systems. The fact that human errors become the major cause of large accidents is in common in large scale engineering systems, and the development of the operation support system for preventing it has become an important research subject. Also the research on design support system and maintenance support system is in progress to prevent human errors. Operation support system is composed of diagnostic system, operation guide system, man-machine interface and knowledge data base, and throughout these, the research on the human errors arising in the process of human decision making becomes the basis. Rasmussen's model for decision making, the classification of human errors and the reliability analysis for men, the factors affecting human errors, the acquisition of knowledge, the compilation and management of knowledge data base, the diagnostic system, operation guide system and man-machine interface are described. (K.I.)
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Energy Technology Data Exchange (ETDEWEB)
Topcuoglu, S.; Birol, E. (Cekmece Nuclear Research and Training Center, Istanbul (Turkey))
1982-12-01
The bioaccumulation of labelled surfactant, 35S-labelled sodium lauryl sulfate and 65Zn-labelled zinc chloride, was investigated both as a mixture and alone by themselves in young goby. The concentration factor of 7.15 was calculated for the surfactant in the whole-body fish and there was no effect of zinc chloride on this bioaccumulation process. Biological half-life of the surfactant was around 35 hours. The effects of surfactants on the zinc accumulation were also followed under the same conditions. The results indicated that the sodium lauryl sulfate had no effect on the accumulation of zinc, however, the other surfactant, linear alkylbenzene sulfonate, caused a significant increase in the zinc accumulation in comparison with the control group, during the uptake period.
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International Nuclear Information System (INIS)
Topcuoglu, S.; Birol, E.
1982-01-01
The bioaccumulation of labelled surfactant, 35S-labelled sodium lauryl sulfate and 65Zn-labelled zinc chloride, was investigated both as a mixture and alone by themselves in young goby. The concentration factor of 7.15 was calculated for the surfactant in the whole-body fish and there was no effect of zinc chloride on this bioaccumulation process. Biological half-life of the surfactant was around 35 hours. The effects of surfactants on the zinc accumulation were also followed under the same conditions. The results indicated that the sodium lauryl sulfate had no effect on the accumulation of zinc, however, the other surfactant, linear alkylbenzene sulfonate, caused a significant increase in the zinc accumulation in comparison with the control group, during the uptake period. (author)
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Directory of Open Access Journals (Sweden)
Tatyana I. Tsymbalyuk
2012-03-01
Full Text Available The pollen morphology of Suaeda acuminata , S. prostratа and Tamarix ramosissima from Ukrainian flora has been studied with light and scanning electron microscopy. The main morphological features of pollen grains of three taxa, which spread within halophytes vegetation, are determined. The results has considered as potential useful for identification of the fossil pollen under paleopalynological or paleoecological study.
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Directory of Open Access Journals (Sweden)
LOYOLA NELSON EDUARDO
2012-04-01
Full Text Available
In cut flowers, there must be clear guidelines for export, therefore, it is essential to proper postharvest management, to store the flowers for as long as possible in top condition, both for transit and vase life; in Chile there is very little knowledge about this operation. In order to address these questions, a study was conducted to evaluate the performance of postharvest life of the peony cultivar ‘Karl Rosenfield’, using four treatments: water, preharvest Borocal® with water, Borocal® with 100 g sucrose/L of water, and 100 g sucrose/L of water, some of which had Borocal® added preharvest and sucrose applied postharvest; evaluating four quality parameters in cut flowers: floral diameter, stem curvature, stem weight and vase life. The present study lasted 25 days, which was the total time of refrigerated storage. The results showed that peony stems with preharvest applications of Borocal® and postharvest applications of only water presented the highest values in terms of floral diameter, stem weight and particularly increased vase life, with no significant differences in stem curvature.
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Managing ADHD in Adulthood: A Meta-Synthesis of How Adults Diagnosed With ADHD Manage
DEFF Research Database (Denmark)
Bjerrum, Merete; Larsen, Palle; Pedersen, Preben Ulrich
, manage to live, life impairment, social life skills, attitude, coping behaviour, academic functioning, social adjustment, interpersonal relation, family health, social support, adult 19-44 years, middle aged 45-64 years. Results Four themes emerged from the included studies: ‘Being different from others......Managing ADHD in adulthood A meta-synthesis of how adults diagnosed with ADHD manage life with the symptoms Merete Bjerrum, Associate Professor, PhD, Department of Public Health, Aarhus University, Denmark and Danish Centre for Systematic Review in Nursing; Palle Larsen, MScN, PhD-student, Deputy....... But how do the adult experience ADHD symptoms affect the management of daily life skills? And which factors support their ability to manage the symptoms? Aim Our aim is to synthesise the existing literature to investigate how adults experience and manage life with ADHD, and to study the protective factors...
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Dieterich, Axel; Mörtl, Martin; Eckmann, Reiner
2004-07-01
Complex habitat structures can influence the foraging success of fish. Competition for food between fish species can therefore depend on the competitors' abilities to cope with structural complexity. In laboratory experiments, we comparatively assessed effects of zebra mussels (Dreissena polymorpha Pall.) on the foraging success of Eurasian perch (Perca fluviatilis L.) and ruffe (Gymnocephalus cernuus (L.)). In single-species and mixed-species experiments, the fish were fed caddisfly larvae (Tinodes waeneri (L.)) over complex (mussel-covered stones) and less-complex (bare stones) substrates. With intraspecific competition, food consumption by perch and ruffe decreased significantly when the complex substrate was used. With interspecific competition, food consumption by perch and ruffe did not change with substrate complexity, but perch clearly out-competed ruffe on both substrates. Zebra mussel beds provide a refuge for macrozoobenthos against predation by ruffe and probably also by perch. (
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Directory of Open Access Journals (Sweden)
Siti Nurhidayatul hasanah
2015-06-01
Full Text Available In the presence a portion student that declares for that Indonesian study really palls is fairly, since they have perceived can and forwarding material which unattractive so at second hand student become arrest deep frail that material. As teacher of Indonesian was necessarily feels happening learning problem all this time. So teacher necessarily tries do changes in Indonesian learning at within class. One of change which is done by use of method role play and STAD'S method (Student Teams Achievement division in standart interest converses and reading. In learning Tells hobby, can be done by use of method role play so makes student more active. Method role play understanding language as skill of straightforward speaking with bases student life in masayarakat. Method role play well-matched being applied while teacher does speaking learning with aided with role card.
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JACOS: AI-based simulation system for man-machine system behavior in NPP
Energy Technology Data Exchange (ETDEWEB)
Yoshida, Kazuo; Yokobayashi, Masao; Tanabe, Fumiya [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment; Kawase, Katsumi [CSK Corp., Tokyo (Japan); Komiya, Akitoshi [Computer Associated Laboratory, Inc., Hitachinaka, Ibaraki (Japan)
2001-08-01
A prototype of a computer simulation system named JACOS (JAERI COgnitive Simulation system) has been developed at JAERI (Japan Atomic Energy Research Institute) to simulate the man-machine system behavior in which both the cognitive behavior of a human operator and the plant behavior affect each other. The objectives of this system development is to provide man-machine system analysts with detailed information on the cognitive process of an operator and the plant behavior affected by operator's actions in accidental situations of a nuclear power plant. The simulation system consists of an operator model and a plant model which are coupled dynamically. The operator model simulates an operator's cognitive behavior in accidental situations based on the decision ladder model of Rasmussen, and is implemented using the AI-techniques of the distributed cooperative inference method with the so-called blackboard architecture. Rule-based behavior is simulated using knowledge representation with If-Then type of rules. Knowledge-based behavior is simulated using knowledge representation with MFM (Multilevel Flow Modeling) and qualitative reasoning method. Cognitive characteristics of attentional narrowing, limitation of short-term memory, and knowledge recalling from long-term memory are also taken into account. The plant model of a 3-loop PWR is also developed using a best estimate thermal-hydraulic analysis code RELAP5/MOD2. This report is prepared as User's Manual for JACOS. The first chapter of this report describes both operator and plant models in detail. The second chapter includes instructive descriptions for program installation, building of a knowledge base for operator model, execution of simulation and analysis of simulation results. The examples of simulation with JACOS are shown in the third chapter. (author)
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(Academic) preparation of/for students
DEFF Research Database (Denmark)
Singla, Rashmi; Engstrøm, Emma; Sandermann, Weibke
This paper contributes to an understanding of cultural intervention across geographical borders based on two cases from the academic setting of RUC. The first is about preparation of university students, who would be future health workers in NGOs, the private sector and governmental organizations......, through a course -Global Health: promotion, practice and power (Singla & Mubanda Rasmussen, forthcoming). The second case includes international bachelor students’ experiences of encountering the self and other within and beyond the socio-academic sphere (Engstrøm & Sandermann, 2016). The common aspects...... to cultural background and phenotypes. Lastly transformations in the socio-academic spheres for more inclusive encounters are discussed, through more (co-)organization about privileges, institutional racism on the personal, group and structural level against the backdrop of reflexivity. Word count- 250...
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Directory of Open Access Journals (Sweden)
Richard A. Prayson
2012-01-01
Full Text Available Rasmussen’s encephalitis is a well-established, albeit rare cause of medically intractable epilepsy. In a small number of Rasmussen's cases, a second pathology is identified, which independently can cause medically intractable seizures (dual pathology. This paper documents a case of a 13-year-old male who presented with medically intractable epilepsy. The patient underwent a series of surgical resections, early on resulting in a diagnosis of focal cortical dysplasia and later yielding a diagnosis of coexistent Rasmussen’s encephalitis, marked by chronic inflammation, microglial nodules, and focal cortical atrophy, combined with focal cortical dysplasia (Palmini et al. type IIA, ILAE type IIA. The literature on dual pathology in the setting of Rasmussen’s encephalitis is reviewed.
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DEFF Research Database (Denmark)
Rasmussen, Claus; Thomas, Jennifer C.; Engel, Michael S.
2017-01-01
and is more closely related to Lepidotrigona Moure. The species is transferred to Wallacetrigona Engel and Rasmussen, new genus, and differentiated from Geniotrigona proper as well as all other meliponines occurring in Sundaland, Wallacea, and Sahul (Australinea). The new genus occurs east of the Wallace Line...... and separate from the distribution of Geniotrigona, which is otherwise restricted to Sundaland, but Wallacetrigona is presently not known beyond the Weber Line. A hierarchical classification of Indomalayan and Australasian stingless bees is tabulated and a revised key to the genera and subgenera provided......, as well as an appendix tabulating the species and synonyms. The following new combinations are established: Wallacetrigona incisa (Sakagami and Inoue), Homotrigona (Lophotrigona) canifrons (Smith), Homotrigona (Odontotrigona) haematoptera (Cockerell), Homotrigona (Tetrigona) apicalis (Smith), H. (T...
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Inhibition of coagulation factors by recombinant barley serpin BSZx
DEFF Research Database (Denmark)
Dahl, Søren Weis; Rasmussen, S.K.; Petersen, L..C.
1996-01-01
Barley serpin BSZx is a potent inhibitor of trypsin and chymotrypsin at overlapping reactive sites (Dahl, S.W., Rasmussen, S.K. and Hejgaard, J. (1996) J. Biol, Chem., in press), We have now investigated the interactions of BSZx with a range of serine proteinases from human plasma, pancreas......, urokinase and tissue type plasminogen activator, plasmin and pancreas kallikrein and elastase were not or only weakly affected, The inhibition pattern with mammalian proteinases reveal a specificity of BSZx similar to that of antithrombin III. Trypsin from Fusarium was not inhibited while interaction...... with subtilisin Carlsberg and Novo was rapid but most BSZx was cleaved as a substrate, Identification of a monoclonal antibody specific for native BSZx indicate that complex formation and loop cleavage result in similar conformational changes....
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The status of taxonomy and venom in sea snakes
DEFF Research Database (Denmark)
Redsted Rasmussen, Arne; Sanders, Kate L.
2017-01-01
The status of taxonomy and venom in sea snakesArne R Rasmussen1, Kate L Sanders21 The Royal Danish Academy of Fine Arts, School of Architecture, Design & Conservation, Copenhagen, Denmark2 School of Earth and Environmental Sciences, University of Adelaide, Adelaide, South Australia 5000, Australia......, the Aipysurus group was separated from the other viviparous sea snakes at around 5.8 million years before present and in the Hydrophis lineage the Hydrophis group was separated from the three semi-marine lineages at around 4.4 million years before present. The venoms of sea snakes are rather simple, typically...... containing a-neurotoxins and phospholipases A2 (PLA2s), and in terms of lethality are known to be more potent than the venoms from terrestrial snakes....
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DEFF Research Database (Denmark)
Skov, Kirsten; Buhl, Mie
into account. Our discussion of the potential for developing digital learning application from a collaborative approach is based on the visual design products, interviews and written reports, as well as shared experiences from the stakeholders in the project. Results: The project revealed three digital visual......=pdf Dunleavy, M. & Dede, C. (2014). Augmented reality teaching and learning. in. J.M. Spector, M.D. Merrill, J. Elen & M.J. Bishop (eds), The handbook og research for educational communications and technology New York: Springer http://isites.harvard.edu/fs/docs/icb.topic1116077.files....../DunleavyDedeARfinal.pdf Rasmussen, H. (2015). Digital Picture Production and Picture aesthetic Competency in It-didactic Design. Risk and opportunities for visual arts education in Europe. Proceedings, InSEA conferene, Lisbon, Portugal...
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Human cognitive task distribution model for maintenance support system of a nuclear power plant
Energy Technology Data Exchange (ETDEWEB)
Park, Young Ho
2007-02-15
In human factors research, more attention has been devoted to the operation of nuclear power plants (NPPs) than to their maintenance. However, human error related to maintenance is 45% among the total human errors from 1990 to 2005 in Korean nuclear power plants. Therefore, it is necessary to study human factors in the maintenance of an NPP. There is a current trend toward introducing digital technology into both safety and non-safety systems in NPPs. A variety of information about plant conditions can be used digitally. In the future, maintenance support systems will be developed based on an information-oriented NPP. In this context, it is necessary to study the cognitive tasks of the personnel involved in maintenance and the interaction between the personnel and maintenance support systems. The fundamental purpose of this work is how to distribute the cognitive tasks of the personnel involved in the maintenance in order to develop a maintenance support system that considers human factors. The second purpose is to find the causes of errors due to engineers or maintainers and propose system functions that are countermeasures to reduce these errors. In this paper, a cognitive task distribution model of the personnel involved in maintenance is proposed using Rasmussen's decision making model. First, the personnel were divided into three groups: the operators (inspectors), engineers, and maintainers. Second, human cognitive tasks related to maintenance were distributed based on these groups. The operators' cognitive tasks are detection and observation; the engineers' cognitive tasks are identification, evaluation, target state, select target, and procedure: and the maintainers' cognitive task is execution. The case study is an analysis of failure reports related to human error in maintenance over a period of 15years. By using error classification based on the information processing approach, the human errors involved in maintenance were classified
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Human cognitive task distribution model for maintenance support system of a nuclear power plant
International Nuclear Information System (INIS)
Park, Young Ho
2007-02-01
In human factors research, more attention has been devoted to the operation of nuclear power plants (NPPs) than to their maintenance. However, human error related to maintenance is 45% among the total human errors from 1990 to 2005 in Korean nuclear power plants. Therefore, it is necessary to study human factors in the maintenance of an NPP. There is a current trend toward introducing digital technology into both safety and non-safety systems in NPPs. A variety of information about plant conditions can be used digitally. In the future, maintenance support systems will be developed based on an information-oriented NPP. In this context, it is necessary to study the cognitive tasks of the personnel involved in maintenance and the interaction between the personnel and maintenance support systems. The fundamental purpose of this work is how to distribute the cognitive tasks of the personnel involved in the maintenance in order to develop a maintenance support system that considers human factors. The second purpose is to find the causes of errors due to engineers or maintainers and propose system functions that are countermeasures to reduce these errors. In this paper, a cognitive task distribution model of the personnel involved in maintenance is proposed using Rasmussen's decision making model. First, the personnel were divided into three groups: the operators (inspectors), engineers, and maintainers. Second, human cognitive tasks related to maintenance were distributed based on these groups. The operators' cognitive tasks are detection and observation; the engineers' cognitive tasks are identification, evaluation, target state, select target, and procedure: and the maintainers' cognitive task is execution. The case study is an analysis of failure reports related to human error in maintenance over a period of 15years. By using error classification based on the information processing approach, the human errors involved in maintenance were classified
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Posttraumatic Stress Disorder, Parenting, and Marital Adjustment among a Civilian Population
Directory of Open Access Journals (Sweden)
Michal Hershkowitz
2017-10-01
Full Text Available While psychopathology in general is linked to poorer marital and parental satisfaction, there is a paucity of data regarding these interactions in parents with Posttraumatic stress disorder (PTSD. The current study addresses this issue among a civilian population. Two hundred trauma-exposed parents, mean age of 37.2, 62% mothers, were assessed using self-report questionnaires, for background variables, PTSD symptoms using the Posttraumatic Stress Diagnostic Scale (PDS, depression symptoms (Beck Depression Inventory, BDI, marital satisfaction (Dyadic Adjustment Scale, DAS-7, parenting behavior (Alabama Parenting Questionnaire, APQ-9, and parenting satisfaction (Parenting Satisfaction Questionnaire. We hypothesized that positive parenting behavior and parenting satisfaction would be negatively correlated with PTSD symptom levels, and that this relationship would be mediated by marital satisfaction; the independent effects of depression on marital and parenting functioning were also examined. Data was analyzed using structural equation modeling (SEM. Results indicated that PTSD was related to poorer parenting behavior (B = 0.089, p = 0.033, depression had a negative impact on parenting satisfaction (B = 0.983, p = 0.003, and marital satisfaction (B = −0.672, p = 0.004, and marital satisfaction fully mediated the relationship between depression and parenting. The findings demonstrated that the effects of PTSD can cast a pall not only over the individual but over the entire family. Interventions are needed to address these issues.
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Cell-baswd non-invasive prenatal testing
DEFF Research Database (Denmark)
Uldbjerg, Niels; Singh, Ripudaman; Christensen, Rikke
that fetal cells are stable in blood samples stored up to 48 hours. Using these cells, we have detected subchromosomal abnormalities including one with mosaic 45, X/46, X, r(X) which have been confirmed at DNA from chorion villus sampling. Conclusions: We conclude that fcmb-NIPT deserves full attention......CONTROL ID: 2520273 ABSTRACT FINAL ID: OC06.03 TITLE: Cell based Non-invasive Prenatal Testing (NIPT) AUTHORS (FIRST NAME, LAST NAME): Niels Uldbjerg2, Ripudaman Singh4, Rikke Christensen3, Palle Schelde4, Ida Vogel1, Else Marie Vestergaard3, Lotte Hatt4, Steen Kølvrå4 INSTITUTIONS (ALL): 1...... therefore hypothesize that NIPT based on amplified DNA from fetal cells circulating in maternal blood (fcmb-NIPT) will make it possible to detect subchromosomal aberrations. Methods: We obtained 30 ml of whole blood from 100 pregnant women undergoing chorion villus sampling at a gestational age of 10...
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DEFF Research Database (Denmark)
Henkel, Heiko
2010-01-01
A closer look at the Muhammad cartoon crisis illuminates some of the key issues that were, and continue to be, at stake for the various actors in the public contestations over the legitimate place of Muslims (and the Islamic tradition) in Danish society. Using a conceptual framework developed...... by Axel Honneth, I suggest in this article that the cartoon crisis is part of an ongoing struggle for recognition in Denmark, through which the terms by which Muslims residing in Denmark are recognized as legitimate citizens/residents of Danish society are negotiated—and on which Muslims may recognize...... the demands of Danish majority society as legitimate. As much as the cartoon affair was an event that, as Palle Weis (2006) writes, “suddenly” ruptured Danish society in 2005, it was therefore also part of a process that continues to shape social actors and their relationships....
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[Fungi isolated from diseased medicinal plants].
Sato, T; Matsuhashi, M; Iida, O
1992-01-01
One hundred and forty-four fungal isolates were obtained from diseased Paeonia albiflora Pall. var. trichocarpa Bung., Astragalus membranaceus Bung., Lithospermum erythrorhizon Sieb. et Zucc., Ledebouriella seseloides Wolff and Bupleurum falcatum L. which were collected in the test field of Tsukuba Medicinal Plant Research Station, National Institute of Hygienic Sciences. Most of them were identified into 15 genera containing 8 species. Fungal species presumed to be pathogens of the host plants were as follows: Cladosporium paeoniae, Pestalotia paeoniicola, Glomerella cingulata, Hainesia lythri, Guignardia sp. and Alternaria sp. from P. albiflora, Fusarium spp., Rhizoctonia spp. and Neocosmospora vasinfecta from A. membranaceus, Colletotrichum gloeosporioides from L. erythrorhizon, Rhizoctonia sp., Fusarium spp., Phoma sp. and Pyrenochaeta sp. from L. seseloides, and Fusarium sp., Alternaria alternata, Phyllosticta sp., Phoma sp., Phomopsis sp. and C. gloeosporioides from B. falcatum. Roots of B. falcatum were found to be parasitized by Meloidogyne sp.
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TESTING OF A FULL-SCALE ROTARY MICROFILTER FOR THE ENHANCED PROCESS FOR RADIONUCLIDES REMOVAL
Energy Technology Data Exchange (ETDEWEB)
Herman, D; David Stefanko, D; Michael Poirier, M; Samuel Fink, S
2009-01-01
Savannah River National Laboratory (SRNL) researchers are investigating and developing a rotary microfilter for solid-liquid separation applications in the Department of Energy (DOE) complex. One application involves use in the Enhanced Processes for Radionuclide Removal (EPRR) at the Savannah River Site (SRS). To assess this application, the authors performed rotary filter testing with a full-scale, 25-disk unit manufactured by SpinTek Filtration with 0.5 micron filter media manufactured by Pall Corporation. The filter includes proprietary enhancements by SRNL. The most recent enhancement is replacement of the filter's main shaft seal with a John Crane Type 28LD gas-cooled seal. The feed material was SRS Tank 8F simulated sludge blended with monosodium titanate (MST). Testing examined total insoluble solids concentrations of 0.06 wt % (126 hours of testing) and 5 wt % (82 hours of testing). The following are conclusions from this testing.
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DEFF Research Database (Denmark)
Rasmussen, Henrik K.; Ghasemi, Ismaeil; Szabo, Peter
2003-01-01
One of the most important post-reactor modifications of polyethylene is cross-linking. Cross-linking improves some properties of polyethylene such as: environmental stress cracking resistance (ECSR), chemical and abrasion resistance, service temperature etc. In this study the rheological variation...
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Bosquejo histórico de la Cefalometría Radiográfica Historical sketch of radiographic cephalometry
Directory of Open Access Journals (Sweden)
Alberto Companioni Bachá
2008-06-01
Full Text Available La cefalometría es un elemento importante en la conformación de una documentación ortodóncica para elaborar un diagnóstico y un plan de tratamiento adecuado. Con el descubrimiento de los rayos X, el 8 de noviembre de 1895 por Wilhhelm Conrad Roentgen, y la existencia de técnicas que precedieron a los rayos X, como la craneometría y la antropología, es que los ortodoncistas pueden contar con esta herramienta diagnóstica de inestimable valor. En el perfeccionamiento de la técnica cefalométrica y de sus análisis contemporáneos ha sido importante el concurso de diversos autores entre los que se destacan Broadbent, Bolton, Hofrath, Korkhaus, Ubaldo Carrea, De Nevreze, Paul Simon y Dreyfus, Margolis, Weingart, Thurow, Bjork, Freeman-Rasmussen, Reboul, Steiner, Andrews, Ricketts, Holdaway, McNamara, Interlandi, entre otros. Este trabajo se propone hacer un recuento de los hechos más significativos que acompañaron la evolución y desarrollo de la cefalometríaCephalometry is an important element to take into account at the time of preparing an orthodontic documentation in order to make a diagnosis and an adequate treatment plan. Thanks to the discovery of X-rays on November 8, 1895 by Wilhhelm Conrad Roentgen, and to the existence of techniques that preceded the X-rays, such as craniometry and anthropology, orthodontists may use this diagnostic tool of great value. In the improvement of the cephalometric technique and its contemporary analyses it has been important the collaboration of various authors, among whom Broadbent, Bolton, Hofrath, Korkhaus, Ubaldo Carrea, De Nevreze, Paul Simon and Dreyfus, Margolis, Weingart, Thurow, Bjork, Freeman-Rasmussen, Reboul, Steiner, Andrews, Ricketts, Holdaway, McNamara and Interlandi, stand out. This paper intends to make an account of the most significant events related to the evolution and development of cephalometry
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Yang, Xu; Wu, Qinfen; Lai, Chin-Hui; Wang, Xin
2017-10-01
We present a modified tension band technique combined with cable cerclage using Cable Grip System for the treatment of displaced inferior patellar pole fractures and report the knee functional outcome. The patients who had had operative treatment of a displaced inferior patellar pole fracture (AO/OTA 34-A1) between December 2013 and December 2015 were studied retrospectively. Eleven consecutive patients had had open reduction and internal fixation with the modified technique using Cable Grip System, of whom, five males and six females with an average age of 60.9 years (range, 29-81 years). All fractures occurred from direct fall onto the knee. The average time from injury to surgery was 6.1days (range, 2-12days). The range of motion (ROM) was measured in degrees by goniometry at postoperative intervals of 1, 2, 4, 12, and 48 weeks; Knee function was evaluated using the Rasmussen scores at final follow-up. No patients had nonunion, loss of reduction, migration of wire, irritation from the implant and fixation breakage during the follow-up period. Recovery of ROM was achieved at 12 weeks, with the average ROM at 1 week was 72° (range, 65°-78°), 86.4° (range, 78°-92°) at 2 weeks, 115.5° (range, 103°-122°) at 4 weeks, 129.6° (range, 122°-133°) at 12 weeks, 134.5° (range, 129°-139°) at 48 weeks after the operation. Concerning the knee function outcome assessment, all patients showed excellent results at final follow-up. The average Rasmussen scores was 27.9 out of 30 (range, 27-29). The modified tension band technique combined with cable cerclage using Cable Grip System for displaced inferior patellar pole fractures can provide stable fixation with excellent results in knee function, allows for immediate mobilization and early weight-bearing, which is a simple and valuable technique in routine clinical practice. Copyright © 2017 Elsevier Ltd. All rights reserved.
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International Nuclear Information System (INIS)
Peters, H.P.; Renn, O.
1983-01-01
The perception of risk has become a mayor research field, after scientists and politicians recognized that scientific risk studies like the Rasmussen-Report on nuclear energy had no large impact on the public acceptance. With our surveys we aimed to combine two methodological approaches (object perception and attitude theory) and to develop a technique in which the psychic process of perceiving and assessing risk-objects by the general public was followed up and analyzed. Psychological experiments in the field of isolating relevant factors of qualitative risk properties as well as demographic surveys for the measurement of the belief structure were carried out. Our results indicate that in objection to the common conception by natural scientists people in general have a good estimative ability to judge the expected value of different risks. But beyond this estimation of fatalities people also use other criteria (like personal control) to order different objects in respect to their riskiness. The perceived risk is but one factor influencing attitude. A simplified model of the acceptance-building process is carried out showing that acceptance-building is not a purely individual process. Individuals are linked together by their social environment so that every individual decision is influenced by the decision of other people
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International Nuclear Information System (INIS)
Sadia, S.; Zhang, J.T.; Bai, X.; Shedayi, A.A.; Tariq, A.
2017-01-01
Gentiana macrophylla, native to mountainous areas of Central and Southern Asia, is most popular remedy for rheumatism and pains in Traditional Chinese Medicine with an extensive demand in local market. Our study aimed to classify G. macrophylla communities and to find out the impact of topographic and soil factors on their diversity and distribution in Dongling mountain meadow, Beijing, China. Seventy five samples in 15 transects separated by 50m distance in altitude along an elevation gradient (1592-2298m) were established by quadrate method. TWINSAPN and CCA were used for classification and ordination, respectively. Six diversity indices (Species richness, Shannon-Weiner heterogeneity, Simpson’s index, Hill’s index, Pielou evenness and McIntosh evenness) were used to analyze the pattern of species diversity and polynomial regression analysis was used to establish their relationship with environmental variables. TWINSPAN classified G. macrophylla communities into 8 types and CCA indicated that soil pH, soil temperature, soil type, disturbance, total N, total K, Mg and Zn were significantly related to these communities. Elevation was the most significant factor that affecting the diversity and distribution of G. macrophylla communities. Significant effect of environment, topography and disturbance to meadow communities of G. macrophylla highly suggests some important measures such as uprooting restriction, tourism limitation in meadow area, monitoring of functional diversity, fertilization, irrigation, cloning and cultivation to protect and conserve it and its communities to be used in medicine industry. (author)
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National Research Council Canada - National Science Library
Snyder, Jr., Carl E; Gschwender, Lois J; Gunderson, Stephen L; Fultz, George W
2006-01-01
.... This report describes a project that evaluated the effectiveness of various hydraulic fluid purification process configurations on the removal of water and particulate contaminants from MIL-PRF-83282...
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Probabilistic risk assessment (PRA) on the effectiveness of a core rescue system (SSN) for PWRs
International Nuclear Information System (INIS)
Petrangeli, G.; Valeri, A.
1983-01-01
Safety systems for the prevention of LWR core severe damage have recently been studied, which are based on automatic primary system depressurization and on borated water injection by low pressure accumulators. These systems have been named Core Rescue System (SSN). The present study evaluates the reduction in core melt probability brought about by the installation of a SSN system on the RSS (WASH 1400) PWR plant (Surry 1). The calculated result is a core melt probability reduction factor of about 250. Taking into account the possible effect of external or internal unknown events of negligible, yet undefined, probability it is concluded that a SSN system can make a plant ten times safer. The first part of a review report by Prof. N.C.Rasmussen, MIT, dealing with general comment, is attached
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DEFF Research Database (Denmark)
Sanden, Guro Refsum
.g. Barner-Rasmussen & Aarnio, 2011), and by drawing on interview and document data from the companies’ communication departments, this study investigates whether headquarters staff make any particular considerations in their blue-collar communication. The findings – which are discussed on the basis......The present study examines how two Danish manufacturing companies – Grundfos and ECCO – communicate corporate information to blue-collar employees located in foreign production units. Blue-collar employees have been found to have lower foreign language skills than white-collar employees (e...... of communication accommodation theory (CAT) (Giles & Wiemann, 1987) – reveal that communication professionals at headquarters converge towards blue-collar employees in three distinct ways: in the form of stylistic, linguistic, and modal convergence. The findings also suggest that the need for convergence arises...
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HTGR accident initiation and progression analysis status report. Volume 1. Introduction and summary
International Nuclear Information System (INIS)
Raabe, P.H.; Houghton, W.J.; Joksimovic, V.
1976-01-01
Probabilistic risk assessment techniques have been applied to obtain guidance in choosing nuclear safety research and development that is most worthwhile for high-temperature gas-cooled reactor (HTGR) nuclear power plants. The probabilistic techniques used are similar to those employed in the Reactor Safety Study for light water reactors (LWRs), WASH-1400, directed by Dr. N. C. Rasmussen. The recommendations for research include studies related to core heatup even though this event poses a very low risk to the public. In fact, it was found that under the many conditions covered by the study to date, even very infrequent accidents in HTGRs (say, once in ten million years) will not produce fatalities. Potential cost reduction areas have been found where alternate design options protect the public and meet regulatory safety criteria
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A Web-based multimedia collaboratory. Empirical work studies in film archives
DEFF Research Database (Denmark)
Pejtersen, A.M.; Albrechtsen, H.; Cleal, B.
2001-01-01
and interfaces for collaborative work and content-based access to digital repositories for film archives, researchers and end-users. This report is based on empirical analysis of three film archives inGermany, Austria and the Czech Republic, and seeks to elicit the user needs for a collaboratory in this domain....... Both the collection and analysis of data have been organised according to principles of Cognitive Work Analysis (CWA) as pioneered at Risø (cf.Rasmussen, Pejtersen and Goodstein 1994). Research based work on individual film projects is, due to international distribution and multiple versions, dependent......The Collaboratory for Annotation, Indexing and Retrieval of Digitized Historical Archive Material (Collate) is intended to foster and support collaboration on research, cultural mediation and preservation of films through a distributed multimediarepository. The tool will provide web-based tools...
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Evaluation of ITS2 for intraspecific identification of Paeonia lactiflora cultivars
Directory of Open Access Journals (Sweden)
Qian Li
2017-09-01
Full Text Available Herbaceous peony (Paeonia lactiflora Pall. is an important ornamental and medicinal plant. DNA barcodes can reveal species identity via the nucleotide diversity of short DNA segments. In this study, two main candidate DNA barcodes (ITS2 and psbA-trnH were tested to identify twenty-one cutting cultivars of P. lactiflora and their wild species. The efficacy of the candidate DNA barcodes was assessed by PCR amplification, sequence quality, sequence diversity, rate of correct identification, and phylogenetic analysis. ITS2 was easy to be amplified and sequenced among the samples. The identification by Blastn and phylogenetic analysis was 95.4% and 63.6%, respectively. For psbA-trnH, the presence of poly A-T led to sequencing failure which limited its use as DNA barcode candidate. Moreover, the authentic efficiency of psbA-trnH was lower than ITS2. The results showed that ITS2 is suitable as a candidate DNA barcode for the intraspecific identification of P. lactiflora cultivars.
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HPP Boshkov Most - upgrading of the design installed capacity from 45 MW to 70 MW
International Nuclear Information System (INIS)
Pavleski, Vlatko; Jakimova Filipovska, Nevenka; Ivanova-Davidovicj, Jasna
2007-01-01
HPP Boshkov Most location will be near the town of Debar, accessible from Mavrovo-Debar road. This procject involves the tributaries that combine to make up the Mala Reka, the biggest tributary to Radika river. The watershed area is characterized as having high mountains and rich watercourses, without major settlements. The hydro system consists of: The Tresonche reservoir with 44 m high dam, with an intake to head race tunnel, also additional intakes linked by a system siphons, covered channels collect the waters from high mountains and deliver their flow to the head race tunnel. The head race tunnel ends with surge shaft and penstocks to the powerhouse. In this paper will be given differences between the Main Design prepared by HEP - Skopje in 1983, where the installed capacity is 45 MW and feasibility Study prepared by Pall C. Rizzo Ass., where installed capacity is suggested to be 70 MW, thru enlarged nominal discharge - from 14 m 3 /s to 22 m 3 /s. (Author)
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Daeschlein, G; Fenske, C; Scholz, S; Dahlke, S; Jünger, M; Kramer, A
2015-01-01
As a result of their mode of filter feeding, zebra mussels (Dreissena polymorpha Pall.) have been observed to purify natural water bodies and in vitro. Therefore, the possibility of using zebra mussels for water purification was investigated in a slightly brackish water body of a large lagoon. In this study, water samples were taken above, near and at distance from zebra mussel beds (MB) in the Odra Lagoon in North East Germany. Near typical bacterial species like Aeromonas spp. pathogenic bacteria with potential relation to hospital wastewater pollution (Burkholderia cepacia, Staphylococcus aureus, Weeksella spp.) were detected. There were no correlations found between either total bacteria or pathogens and distance to MB and no antimicrobial effect of the mussels could be deduced. For bioremediation in larger water bodies like lagoons, natural zebra MB do not seem to play a major antimicrobial role and the effect of artificial mussel grids especially against hospital pathogens should be investigated.
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DEFF Research Database (Denmark)
Nielsen, Steen
2005-01-01
De tre begreber process-costing, job-order-costing, operation-costing samt functional-based costing er faktisk historiske begreber som stammer langt tilbage i økonomistyringslitteraturen, faktisk tilbage til Scientific Management bevægelsen fra 20'erne og 30'erne. Man kan derfor ikke sige, at disse...... ordreregnskabet, f.eks. som dette er analyseret hos Palle Hansen og Vagn Madsen. Begrebet operational costing anvendes også, men dette dækker i realiteten over, hvordan og hvilke elementer der indgår i hele virksomhedens regnskabs-information-system. Dvs. at dette mere er et spørgsmål om, hvordan systemerne er...... Aktivitets-Baseret Cost Management systemerne. Det er derfor vigtigt dels at kende sin historie på området, dels at gøre sig klart, om de under visse antagelser stadig har deres berettigelse. De samme begreber har også deres pendant til de danske begreber, afdelings- eller funktionsregnskabet samt...
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DEFF Research Database (Denmark)
Rasmussen, Henrik Koblitz; Bach, Anders; Hassager, Ole
2002-01-01
We investigate the transient uni-axial eextensional viscosity of polymer melts by means of a filament strecthing rheometer.......We investigate the transient uni-axial eextensional viscosity of polymer melts by means of a filament strecthing rheometer....
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DEFF Research Database (Denmark)
Hermanssdottir, Sunna; Poulsen, Søren Bolvig; Fisker, Anna Marie
2013-01-01
When Charles Eames was asked about the boundaries of design, he replied, “What are the boundaries of problems” (Burns et. al, 2006). This quote pinpoints the wide aspect of design, and as the complexity of society is increasing it becomes important to discuss how design can deal with complex...... and wicked problems (Rittel, 1973; Kolko, 2012) in the process of creating desirable solutions (Fallman, D., 2003) to change food-related behaviour (Abdussalam, Foster and Käferstein, 1989). Food and meals in our environment are embedded in complex physical, social and cultural contexts and there is a need...... to understand how people, spaces and food interact and how this interaction influences food behaviour (Mikkelsen, 2011). This requires transdisciplinarity and holistic approach (Rasmussen and Smidt, 2001), which leads to discussing the possibilities within the combination of the two fields, food and design...
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Cerebral water and ion balance remains stable when humans are exposed to acute hypoxic exercise
DEFF Research Database (Denmark)
Avnstorp, Magnus B; Rasmussen, Peter; Brassard, Patrice
2015-01-01
both circumstances. No cerebral net exchange of Na(+) or K(+) was evident. Likewise, no significant net-exchange of water over the brain was demonstrated and the arterial and jugular venous hemoglobin concentrations were similar. CONCLUSION: Challenging exercise in hypoxia for 30 min affected muscle......Avnstorp, Magnus B., Peter Rasmussen, Patrice Brassard, Thomas Seifert, Morten Overgaard, Peter Krustrup, Niels H. Secher, and Nikolai B. Nordsborg. Cerebral water and ion balance remains stable when humans are exposed to acute hypoxic exercise. High Alt Med Biol 16:000-000, 2015.-Background...... intense exercise is carried out in hypoxia and monitored the influence of muscle metabolism for changes in arterial variables. METHODS: On two separate days, in random order, 30 min cycling exercise was performed in either hypoxia (10% O2) or normoxia at an intensity that was exhaustive in the hypoxic...
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Safety of nuclear power reactors
International Nuclear Information System (INIS)
MacPherson, H.G.
1982-01-01
Safety is the major public issue to be resolved or accommodated if nuclear power is to have a future. Probabilistic Risk Analysis (PRA) of accidental releases of low-level radiation, the spread and activity of radiation in populated areas, and the impacts on public health from exposure evolved from the earlier Rasmussen Reactor Safety Study. Applications of the PRA technique have identified design peculiarities in specific reactors, thus increasing reactor safety and establishing a quide for evaluating reactor regulations. The Nuclear Regulatory Commission and reactor vendors must share with utilities the responsibility for reactor safety in the US and for providing reasonable assurance to the public. This entails persuasive public education and information that with safety a top priority, changes now being made in light water reactor hardware and operations will be adequate. 17 references, 2 figures, 2 tables
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Learning, Leading and Letting go of Control
DEFF Research Database (Denmark)
Jensen, Annie Aarup; Kjær-Rasmussen, Lone Krogh; Iversen, Ann-Merete
Learning, leading and letting go of control – Learner Led Approaches in Education Annie Aarup Jensen, Lone Krogh Kjær-Rasmussen, Ann-Merete Iversen and Anni Stavnskær Pedersen Abstract The aim of the paper is to introduce a new term in teaching in Higher Education: Learner Led Approaches...... in Education: LED. The sources of inspiration are many as are the experiences we draw from. Problem-based project work (PBL) being one, various classical teacher centered methods, and last but not least a variety of methods aiming towards developing creativity, innovational skills and entrepreneurship. LED...... is inspired by collaboration between professors from Aalborg University, Cornwall College and University College of Northern Denmark. Moravec (2008) claims that educational systems still operate in 1.0 or perhaps 2.0 mode while the surrounding cultures and societies operate in 3.0 mode. The amount...
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DEFF Research Database (Denmark)
Buhl, Mie; Skov, Kirsten
. Student art teachers and teacher trainers took part in the design process performed by communication students. The project took its point of the departure in the act of Danish teacher education where student teachers must be educated in the practical use of digital visual media for art practices aiming......, drawing or video. Thus, the project suggested the development of a visual learning design for achieving augmented reality (AR) experiences in urban environments and sharing them on social media. The purpose was to explore adequate approaches to work with digital media in visual arts education based...... on practices and reflective processes. The theoretical framework for our discussion of the empirical project draws on current discussions of learning designs and digital media in visual arts education (Peppler 2010, Rasmussen 2015, Buhl & Ejsing-Duun, 2015; Buhl, 2016). Methodology The choice of empirical...
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A Confession as Clear as Mud? Making Sense of Lance Armstrong’s Revelations
DEFF Research Database (Denmark)
Gleaves, John; Christiansen, Ask Vest
2013-01-01
Researching the world of doping can often feel like work as an undertaker: when business is good, it’s usually bad for someone else. And these past few months have been especially good for business. Confessions from high profile cyclists, including Lance Armstrong and a number of high profile...... Rabobank riders, e.g. Michael Rasmussen, doping scandals in American collegiate sport, a whole cluster of revelations from Australian elite sport and testimonies from the Operacion Puerto trial have added new information about closed doping practices. Moreover, it seems that the complex love......-hate relationship between sporting organizations and their anti-doping programs has pointed towards previously underexplored conflicts of interest. So while the past few months would leave any hungry doctoral student salivating over the wealth of new material, it is important to separate out what has become clearer...
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Nuclear power risks: challenge to the credibility of science
International Nuclear Information System (INIS)
Welch, B.L.
1980-01-01
For a quarter of a century the Federal Government and the nuclear industry have deliberately deceived the American public about the risks of nuclear power. Facts have been systematically withheld, distorted, and obscured, and calculations have been deliberately biased in order to present nuclear power in an unrealistically favorable light. Most persistent and flagrant have been: (a) attempts to normalize public perception of nuclear accident casualties with those of more familiar accidents; and (b) the cloaking of the objectively undocumentable faith of the atomic energy establishment that a nuclear accident is extremely unlikely in a smokescreen of invalid, pseudoquantitative statistical probabilities in order to convince the public that the chance of an accident is negligible. Prime examples of these abuses are found in the Rasmussen report on nuclear reactor safety and in its representation to the public
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Constructions complying with tightened Danish sound insulation requirements for new housing
DEFF Research Database (Denmark)
Rasmussen, Birgit; Hoffmeyer, Dan
New sound insulation requirements in Denmark in 2008 New Danish Building Regulations with tightened sound insulation requirements were introduced in 2008 (and in 2010 with unchanged acoustic requirements). Compared to the Building Regulations from 1995, the airborne sound insulation requirements...... were 2 –3 dB stricter and the impact sound insulation requirements 5 dB stricter. The limit values are given using the descriptors R’w and L’n,w as before. For the first time, acoustic requirements for dwellings are not found as figures in the Building Regulations. Instead, it is stated......), Denmark. [2] "Lydisolering mellem boliger – Nybyggeri" (Sound insulation between dwellings – Newbuild)". Publication expected in April 2011. The guideline is a part of a series of seven new SBi acoustic guidelines. Project leader Birgit Rasmussen. The series shall replace the existing guidelines 1984...
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Learning Objectives for Master's theses at DTU Management Engineering
DEFF Research Database (Denmark)
Hansen, Claus Thorp; Rasmussen, Birgitte; Hinz, Hector Nøhr
2010-01-01
, different. The DTU Study Handbook states that:”Learning objectives are an integrated part of the supervision”, which provides you with the opportunity – naturally in cooperation with your supervisor – to formulate learning objectives for your Master's thesis. There are at least three good reasons for being...... that you formulate precise and useful learning objectives for your Master's thesis. These notes of inspiration have been written to help you do exactly this. The notes discuss the requirements for the learning objectives, examples of learning objectives and the assessment criteria defined by DTU Management...... Engineering as well as, but not least, some useful things to remember concerning your submission and the assessment of the Master's thesis. DTU Management Engineering Claus Thorp Hansen Birgitte Rasmussen Hector Nøhr Hinz © DTU Management Engineering 2010 ISBN nr. 978-87-90855-94-7 This document...
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Integrated Assessment of the impact of Aqueous Contaminant Stressors on Surface Water Ecosystems
DEFF Research Database (Denmark)
McKnight, Ursula S.; Rasmussen, Jes J.; Kronvang, Brian
2011-01-01
ecosystems. Traditional approaches for managing aquatic resources have often failed to account for the potential effects of anthropogenic disturbances on biota. To fulfil the requirements of the EU Water Framework Directive will be challenging, as it is difficult to successfully separate and evaluate all...... pressures stressing an ecosystem. Here, methods for determining ecological status in streams are evaluated to see if they are capable of capturing the effects of stressors potentially affecting ecosystems. Specifically, they are tested on a case study where the effects of physical habitat degradation can...... be ruled out as a stressor on stream ecological conditions (Rasmussen et al., 2011). This study follows earlier work conducted on a Danish case study involving a TCE groundwater plume discharging into a small stream, located in an area with protected drinking water interests (McKnight et al., 2010...
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Variation and correlation of hydrologic properties
Energy Technology Data Exchange (ETDEWEB)
Wang, J.S.Y. [Lawrence Berkeley Lab., CA (United States)
1991-06-01
Hydrological properties vary within a given geological formation and even more so among different soil and rock media. The variance of the saturated permeability is shown to be related to the variance of the pore-size distribution index of a given medium by a simple equation. This relationship is deduced by comparison of the data from Yucca Mountain, Nevada (Peters et al., 1984), Las Cruces, New Mexico (Wierenga et al., 1989), and Apache Leap, Arizona (Rasmussen et al., 1990). These and other studies in different soils and rocks also support the Poiseuille-Carmen relationship between the mean value of saturated permeability and the mean value of capillary radius. Correlations of the mean values and variances between permeability and pore-geometry parameters can lead us to better quantification of heterogeneous flow fields and better understanding of the scaling laws of hydrological properties.
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Training the Trainers - from an EU Perspective
DEFF Research Database (Denmark)
Martinsen, Bodil
of Language and Business Communication at the Aarhus School of Business.The other project participants are from Belgium, Great Britain, Italy, the Netherlands and Spain. The project, whose overall objective is to create the means to obtain competent trainers, is a follow-up to three previous projects (Grotius...... trainers have to be made available to them. The aim of this paper is to present the EU project, AGIS II, Making things happen: Training the trainers of legal interpreters and translators throughout the EU, coordinated by Kirsten W. RAsmussen and Bodil Martinsen, associate professors at the Department...... of legal interpreting. This process includes, among other things, the development of exemplary curricula, course designs, sample lesson plans and teaching materials, which will be presented and discussed/evaluated at a concluding Seminar on training the trainers, which is to be held in Aarhus, Denmark...
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Usage, structure, and substance in the English ditransitive construction
DEFF Research Database (Denmark)
Shibuya, Yoshikata; Jensen, Kim Ebensgaard
on observation of actual usage-patterns of the construction in naturally occurring discourse. Secondly, Hudson very much treats ditransitives as a functional monolith, assuming functional uniformity and ignoring possible functional variation. Thirdly, his analysis is primarily based on formal structure and pays......-substance-cum-semantic-structure, the scenarios encoded by monotransitives and ditransitives (Rasmussen & Jakobsen 1996: 103-105), the participants associated with T-OBJs and D-OBJs are non-uniform (Goldberg 1995, Croft et al. 2001: 583-586, Hopper and Thompson 1980). Unlike Hudson's (1992) syntactic account, a symbolic account would categorize...... at the level of conceptual content. Hudson (1992: 266-268) observes variation in the functionality of D-OBJs depending on the verb, such that, unlike those occurring with give and deny, D-OBJs occurring with peel take on a more adjunct-like function, but gives the construction the monolithic treatment. We...
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DEFF Research Database (Denmark)
Tarnow, Inge; Andreasen, Susanne SH; Olsen, Lisbeth Høier
2010-01-01
Sciences, Faculty of Life Science, University of Copenhagen, Denmark. Chronic congestive heart failure (CHF) in humans is associated with abnormal hemostasis, and changes in hemostatic biomarkers carry a poor prognosis. CHF in dogs has been associated with plasma markers of hypercoagulability, however......CONGESTIVE HEART FAILURE IN DOGS IS ASSOCIATED WITH ENHANCED PLATELET-LEUKOCYTE AGGREGATES - A MARKER FOR PLATELET ACTIVATION. I Tarnow1, LH Olsen2, SHS Andreasen2, SG Moesgaard2, CE Rasmussen2, AT Kristensen1, T Falk2. 1Departments of Small Animal Clinical Sciences and 2Animal and Veterinary Basic......, platelet activation markers have not been investigated in dogs with clinical signs of heart disease. We hypothesized that platelet surface activation markers are higher in dogs with CHF compared to age-matched controls without clinical signs of heart failure. Dogs with compensated congestive heart failure...
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Attempt at a Systemic Design of a Protocell: Connecting information, Metabolism and Container
DEFF Research Database (Denmark)
Albertsen, Anders N.; Maurer, Sarah; Cape, Jonathan
many of the basic characteristics of a living system, but usually lack the gene mediated regulation functions that natural cells possess. To address this issue, we are attempting a systemic approach (Rasmussen, 2004) in implementing a simple, chemical system that contains three major types of molecules...... of the design and the already demonstrated advantages of the systemic approach in unravelling interactions (Declue, 2009; Maurer, 2011) between the components and their significances for the self-maintenance and self-replication of a protocell. References DeClue, MS, Monnard, P-A, Bailey, JA, Maurer, SE, Collis......The minimal requirements for a living system are often listed as follows: i) a living system must have a specific identity and be able to preserve it (compartmentalization) ; ii) it must sustain itself by using energy from its environment to manufacture at least some of its components from...
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International Nuclear Information System (INIS)
Meshkati, N.; Buller, B.J.; Azadeh, M.A.
1994-01-01
A traditional human factors (i.e., microergonomic) approach to complex human-machine systems is only concerned with improving the workstation (user interface) design. This approach, by ignoring the importance of the integration of the user interface with job and organizational design, results in systems which lead, at best, only to sub-optimization and are therefore inherently error- and failure-prone. Such systems, when eventually faced with the concentration of certain fault events, will suffer from this open-quotes resident pathogenclose quotes and, as such, are doomed to failure. Also, when complex technological systems, such as nuclear power plants, move from routine to non-routine (normal to emergency) operation, the controlling operators need to dynamically match the system's new requirements. This mandates integrated and harmonious changes in information presentation (display), changes in (job) performance requirements in part because of operators' inevitable involuntary transition to different levels of cognitive control, and reconfigurations of the operators' team (organizational) structure and communication. It is also demonstrated that the skill, rule, and knowledge (SRK) model, developed by Rasmussen, is a high-potential and powerful framework that could be utilized for the proposed integration purpose. The objective of this research was threefold: (1) using the SRK model, to develop an integrated information processing conceptual framework (for integration of workstation, job, and team design); (2) to evaluate the user interface component of this framework -- the ecological display; and (3) to analyze the effect of operators' individual information processing behavior and decision styles on handling plant disturbances, on their performance and preference for traditional and ecological user interfaces
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Xu, Wei
2007-12-01
This study adopts J. Rasmussen's (1985) abstraction hierarchy (AH) framework as an analytical tool to identify problems and pinpoint opportunities to enhance complex systems. The process of identifying problems and generating recommendations for complex systems using conventional methods is usually conducted based on incompletely defined work requirements. As the complexity of systems rises, the sheer mass of data generated from these methods becomes unwieldy to manage in a coherent, systematic form for analysis. There is little known work on adopting a broader perspective to fill these gaps. AH was used to analyze an aircraft-automation system in order to further identify breakdowns in pilot-automation interactions. Four steps follow: developing an AH model for the system, mapping the data generated by various methods onto the AH, identifying problems based on the mapped data, and presenting recommendations. The breakdowns lay primarily with automation operations that were more goal directed. Identified root causes include incomplete knowledge content and ineffective knowledge structure in pilots' mental models, lack of effective higher-order functional domain information displayed in the interface, and lack of sufficient automation procedures for pilots to effectively cope with unfamiliar situations. The AH is a valuable analytical tool to systematically identify problems and suggest opportunities for enhancing complex systems. It helps further examine the automation awareness problems and identify improvement areas from a work domain perspective. Applications include the identification of problems and generation of recommendations for complex systems as well as specific recommendations regarding pilot training, flight deck interfaces, and automation procedures.
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Representing cognitive activities and errors in HRA trees
International Nuclear Information System (INIS)
Gertman, D.I.
1992-01-01
This paper discusses development of a means by which to present cognitive information in human reliability assessment (HRA) event trees. The descriptions found in probabilistic risk assessments (PRAs) regarding the demands on, and the resulting performance of, nuclear power plant (NPP) crews often make use of the technique for human error rate prediction (THERP), which provides a mechanism, the HRA event tree, for presenting the analyst's conceptualization of the activities underlying performance and the errors associated with that performance. When using THERP, analysts have often omitted the more complex elements of human cognition from these trees. There has yet to be a concerted effort to take theory, principles, and data from cognitive psychology and wed it to the logic structure of the HRA event tree. This paper attempts to do so. The COGENT modeling scheme (cognitively based HRA event trees) adds two taxonomies to the HRA event tree proposed by Swain and Guttman. The first taxonomy, the one proposed by Norman and Reason, describes the type of error committed and implies something about the underlying cognition as well. The second of these, the Rasmussen taxonomy, provides description regarding the skill-based, rule-based, or knowledge-based behavior underlying the execution of tasks. It is not apparent and must be deduced from the pattern of errors exhibited by personnel
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In vivo deposition of ultrafine aerosols in human nasal and oral airways
Energy Technology Data Exchange (ETDEWEB)
Yeh, Hsu-Chi; Swift, D.L. [John Hopkins Univ., Baltimore, MD (United States); Simpson, S.Q. [Univ. of New Mexico, Albuquerque, NM (United States)] [and others
1995-12-01
The extrathoracic airways, including the nasal passage, oral passage, pharynx, and larynx, are the first targets for inhaled particles and provide an important defense for the lung. Understanding the deposition efficiency of the nasal and oral passages is therefore crucial for assessing doses of inhaled particles to the extrathoracic airways and the lung. Significant inter-subject variability in nasal deposition has been shown in recent studies by Rasmussen, T.R. et al, using 2.6 {mu}m particles in 10 human subjects and in our preliminary studies using 0.004-0.15 {mu}m particles in four adult volunteers. No oral deposition was reported in either of these studies. Reasons for the intersubject variations have been frequently attributed to the geometry of the nasal passages. The aims of the present study were to measure in vivo the nasal airway dimensions and the deposition of ultrafine aerosols in both the nasal and oral passages, and to determine the relationship between nasal airway dimensions and aerosol deposition. A statistical procedure incorporated with the diffusion theory was used to model the dimensional features of the nasal airways which may be responsible for the biological variability in particle deposition. In summary, we have correlated deposition of particles in the size range of 0.004 to 0.15 {mu}m with the nasal dimensions of each subject.
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In vivo deposition of ultrafine aerosols in human nasal and oral airways
International Nuclear Information System (INIS)
Yeh, Hsu-Chi; Swift, D.L.; Simpson, S.Q.
1995-01-01
The extrathoracic airways, including the nasal passage, oral passage, pharynx, and larynx, are the first targets for inhaled particles and provide an important defense for the lung. Understanding the deposition efficiency of the nasal and oral passages is therefore crucial for assessing doses of inhaled particles to the extrathoracic airways and the lung. Significant inter-subject variability in nasal deposition has been shown in recent studies by Rasmussen, T.R. et al, using 2.6 μm particles in 10 human subjects and in our preliminary studies using 0.004-0.15 μm particles in four adult volunteers. No oral deposition was reported in either of these studies. Reasons for the intersubject variations have been frequently attributed to the geometry of the nasal passages. The aims of the present study were to measure in vivo the nasal airway dimensions and the deposition of ultrafine aerosols in both the nasal and oral passages, and to determine the relationship between nasal airway dimensions and aerosol deposition. A statistical procedure incorporated with the diffusion theory was used to model the dimensional features of the nasal airways which may be responsible for the biological variability in particle deposition. In summary, we have correlated deposition of particles in the size range of 0.004 to 0.15 μm with the nasal dimensions of each subject
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[An improved reduction technique for depression fractures of lateral tibial plateau].
Wang, Hongchuan; Lou, Hua; Liu, Kai; Jiang, Junwei
2013-01-01
To investigate the improved reduction technique for depression fractures of the lateral tibial plateau and its effectiveness. Between January 2008 and December 2010; 48 patients (48 knees) with depression fractures of the lateral tibial plateau (Schatzker II or III fractures) were treated. There were 32 males and 16 females with an average age of 45.8 years (range, 16-79 years). All fractures were fresh closed fractures, which were caused by traffic accident in 27 cases, by falling from height in 5 cases, by crushing in 8 cases, and by sustained falls in 8 cases. According to Schatzker classification, 29 cases were classified as type II and 19 cases as type III. The lateral cortex was cut off to expose the depression and compacted cancellous bone was elevated to reset the articular surface. After reduction, autologous iliac bone graft and locking plate internal fixation were used. Healing of incision by first intention was achieved in all patients, and no complication occurred. All patients were followed up 1.7 years on average (range, 1-3 years). At last follow-up, the knee extension was (-0.5 +/- 0.3) degrees, and the knee flexion was (136.9 +/- 8.8) degrees. X-ray films showed that the fracture healing time was 52 weeks and no breakage of internal fixation occurred. According to Rasmussen clinical score, the results were excellent in 35 cases, good in 10 cases, and fair in 3 cases. According to Rasmussen radiographical score, the results were excellent in 41 cases, good in 7 cases; there were 41 excellent scores and 7 good scores of articular reduction; all gained good recovery of coronal and sagittal alignment and condylar width. The articular surface collapse was (1.0 +/- 0.7) mm at immediate postoperatively and (1.2 +/- 0.7) mm at last follow-up, showing no significant difference (t = -1.42, P = 0.20), but significant differences were found when compared with that at preoperation [(12.2 +/- 8.0) mm, P fracture reduction and can avoid loss of reduction. The
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DEFF Research Database (Denmark)
Ejlers, Steen Erik
2005-01-01
Grafikeren Ole Søndergaard (f. 1937) er oprindeligt uddannet som skiltemaler. Senere blev han elev af navnkundige skriftformgiver, Kunstakademiets første designprofessor, arkitekturen Gunnar Biilmann Petersen. I 1970'erne etablerede Ole Søndergaard, efter nogle år som medarbejder på Naur Klints...... tegnestue, egen tegnestue i Helsingør. Tegnestuen har i årenes løb stået for mangfoldige grafiske arbejder, hvor Ole Søndergaard ofte selv har tegnet de anvendte logo- og skilteskrifter. Skriftfamilien FF Signa, der fra 2000 er blevet udgivet på FontShop International, er Søndergaards første komplette...... digitale skriftfamilie - med mangfoldige anvendelsemuligheder. Forud ligger adskillige års arbejde, bl.a. støttet af Statens Kunstfond. Artiklen beskriver Biilmanns skole, Ole Søndergaards "før-digitale" alfabeter til bl.a. Helsingør Kommune og Knud Rasmussen-monumentet (på Strandvejen ved Klampenborg nord...
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School Me, School Me Not, Street Me, Street Me Not…
DEFF Research Database (Denmark)
Gravesen, David Thore; Frostholm, Peter Hornbæk
School Me, School Me Not, Street Me, Street Me Not… (1099) David Thore Gravesen, Peter Hornbæk Frostholm ECER 2016, 14. Communities, Families and Schooling in Educational Research, Session: 14 SES 10 A When picking leaves of a marguerite, whilst doing the “she loves me, she loves me not” game, you....... Obviously, the skaters attend the site to skate. But also other, more vulnerable groupings, use the site to socialize, meet peers and perhaps escape an unreliable and risky family arena. One particular group, the self-named Thugz, primarily formed around a number of young boys with non-Danish ethnic...... milieu. With a criminal gang-like behavior (Hoeben & Weerman 2013; Hviid 2007; Rasmussen 2012) involving petty crime and violence, one would think the group members would be indifferent towards their schooling and future careers. This was not the case. The informants proved to be very aware...
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Global temperatures and the global warming ``debate''
Aubrecht, Gordon
2009-04-01
Many ordinary citizens listen to pronouncements on talk radio casting doubt on anthropogenic global warming. Some op-ed columnists likewise cast doubts, and are read by credulous citizens. For example, on 8 March 2009, the Boston Globe published a column by Jeff Jacoby, ``Where's global warming?'' According to Jacoby, ``But it isn't such hints of a planetary warming trend that have been piling up in profusion lately. Just the opposite.'' He goes on to write, ``the science of climate change is not nearly as important as the religion of climate change,'' and blamed Al Gore for getting his mistaken views accepted. George Will at the Washington Post also expressed denial. As a result, 44% of U.S. voters, according to the January 19 2009 Rasmussen Report, blame long-term planetary trends for global warming, not human beings. Is there global cooling, as skeptics claim? We examine the temperature record.
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A cultural turn? Vocational teacher education in Denmark
DEFF Research Database (Denmark)
Duch, Henriette
actors in the field. The actors had different interests, which is also visible in documents. The analysis reveals three main discussions. The first is the loss of ‘situated learning’ or vocational teacher training in vocational colleges. The second is theory of science as a symbol of academization......As part of my Ph.D.-project the field of educational policy is analysed with a focus on the decision process on a change of vocational teacher education (Bourdieu, 1996; Duch and Rasmussen, XX). The process is seen in the light of the Bologna process. Originally, the education of Danish vocational...... teachers was a specialized and non-classified course, now it is classifies as a higher education at level six in the Danish Qualification Framework. The analysis is based on qualitative interviews with representatives of for example vocational teachers and of leaders at vocational colleges – different...
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The status of taxonomy and venom in sea snakes
DEFF Research Database (Denmark)
Redsted Rasmussen, Arne; Sanders, Kate L.
2017-01-01
The status of taxonomy and venom in sea snakesArne R Rasmussen1, Kate L Sanders21 The Royal Danish Academy of Fine Arts, School of Architecture, Design & Conservation, Copenhagen, Denmark2 School of Earth and Environmental Sciences, University of Adelaide, Adelaide, South Australia 5000, AustraliaSea...... snakes form two aquatic groups of snakes with a flat vertically paddle-form tail (sea kraits and viviparous sea snakes). Sea snakes belong to the same family Elapidae, which also includes the terrestrial mambas, cobra, kraits, taipan and brown snake. All elapids are characterized by the anterior position...... of the poison-fangs on the maxillary bone (proteroglyphous). Globally there are some 70 species of sea snake found in the tropical and subtropical waters of the Indian Ocean and the Pacific Ocean. Most species are found in the Indo-Malayan Archipelago, the China Sea, Indonesia, and the Australian region...
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DEFF Research Database (Denmark)
Skjøt, R L; Oettinger, T; Rosenkrands, I
2000-01-01
Culture filtrate from Mycobacterium tuberculosis contains protective antigens of relevance for the generation of a new antituberculosis vaccine. We have identified two previously uncharacterized M. tuberculosis proteins (TB7.3 and TB10.4) from the highly active low-mass fraction of culture filtrate....... The molecules were characterized, mapped in a two-dimensional electrophoresis reference map of short-term culture filtrate, and compared with another recently identified low-mass protein, CFP10 (F. X. Berthet, P. B. Rasmussen, I. Rosenkrands, P. Andersen, and B. Gicquel. Microbiology 144:3195-3203, 1998......), and the well-described ESAT-6 antigen. Genetic analyses demonstrated that TB10.4 as well as CFP10 belongs to the ESAT-6 family of low-mass proteins, whereas TB7.3 is a low-molecular-mass protein outside this family. The proteins were expressed in Escherichia coli, and their immunogenicity was tested...
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'A ‘stain on the […] otherwise good reputation of Denmark'
DEFF Research Database (Denmark)
Villadsen, Lisa Storm
2004, Jørgensen 2009, Villadsen 2011, Kock and Villadsen 2011), political science (Nobles 2008, Lind 2008), and sociology (Olick 2007). Methodically the paper draws on methods of close textual reading (Leff 2004), notions of intertextuality (Jasinski 2001a), and conceptually driven criticism (Jasinski......This paper is a rhetorical critique of Fogh Rasmussen’s 2005 official apology to German refugees seeking asylum in Denmark during WWII who were turned away and thus condemned to a cruel fate in German captivity. The paper draws on theory from the fields of rhetoric (Geisler 2004, Lundberg and Gunn...... of the Nazi occupation of Denmark – with particular focus on a web site created for school children. Further, the speech is read up against a second speech held the day after in which Fogh Rasmussen addressed some of the public criticism launched against the nature of the collective memory promoted...
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DEFF Research Database (Denmark)
Mackey, Abigail L; Rasmussen, Lotte Klejs; Kadi, Fawzi
2016-01-01
muscles of one leg. Muscle biopsies were collected from the vastus lateralis muscles before and after stimulation (2.5 h and 2, 7, and 30 d) and were assessed for satellite cells and regeneration by immunohistochemistry and real-time RT-PCR, and we also measured telomere length. After injury, and compared...... activation of satellite cells and muscle remodeling during large-scale regeneration of injured human skeletal muscle.-Mackey, A. L., Rasmussen, L. K., Kadi, F., Schjerling, P., Helmark, I. C., Ponsot, E., Aagaard, P., Durigan, J. L. Q., Kjaer, M. Activation of satellite cells and the regeneration of human......With this study we investigated the role of nonsteroidal anti-inflammatory drugs (NSAIDs) in human skeletal muscle regeneration. Young men ingested NSAID [1200 mg/d ibuprofen (IBU)] or placebo (PLA) daily for 2 wk before and 4 wk after an electrical stimulation-induced injury to the leg extensor...
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DEFF Research Database (Denmark)
Rasmussen, Henrik Koblitz; Bach, Anders; Almdal, Kristoffer
2003-01-01
Transient and steady elongational viscosity has been measured for two narrow molar mass distribution polystyrene melts of molar masses 200 000 and 390 000 by means of a filament stretching rheometer. Total Hencky strains of about five have been obtained. The transient elongational viscosity rises...
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DEFF Research Database (Denmark)
Rasmussen, Henrik Koblitz; Bach, Anders; Almdal, Kristoffer
2003-01-01
Transient and steady elongational viscosity has been measured for two narrow molar mass distributin polystyrene melts ......Transient and steady elongational viscosity has been measured for two narrow molar mass distributin polystyrene melts ...
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Directory of Open Access Journals (Sweden)
V. G. Lazareva
2016-01-01
Full Text Available The aim of research is to study coenopopulations of Halocnemum strobilaceum on soft salt marshes of the lake "Cagan USN" (Yashkul district, Republic of Kalmykia.Materials and methods. The article presents data on the ontogeny, demographic and spatial structure of H. strobilaceum for practical and theoretical use due to the degradation of pastures and secondary salinity in the water reclamation. Research on coenopopulations of Halocnemum has been carried out according to the methods of studying spatial and demographic structure of the plant phytocenoses (1950, plant collection and herbarization (1977, and making sites of 3x3 meters.Results. Research has allowed us to identify 6 age phases of H. strobilaceum: p, im, v, g1, g2-g3, svg, s, and the ontogenetic state: p - 5%, im - 5%, v - 5%, g1 - 35 %, g2-g3 - 35%, svg - 5%, s - 10%. During the research of coenopopulations of Halocnemum strobilaceum we have revealed the polyvariance ontomorphogenesis phenomenon, which is manifested in the transition of individuals from senile (s age condition, in particular, to senile-virginal-generative (svg. In addition, at this stage, we have observed new shoots, habitually similar to vegetative, able to bloom the following year (the state svg. The analysis of ontogenesis of individuals of Halocnemum strobilaceum has showed the predominance of young (g1 and middle-aged (g2-g3 generative phase.Conclusion. Thus, a temporary rejuvenation of Halocnemum strobilaceum communities at the lake of "Cagan USN" is considered by us as the occurrence of certain adaptations to the effects of different natural and anthropogenic factors. This ability of Halocnemum strobilaceum to quickly restore spatial demographic structure of its coenopopulations indicates the high ecological and biological potential of this kind of dominant on the soft salt marshes.
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Ma, J.; Pendall, E.; Chen, F.
2008-12-01
Reaumuria soongorica is a dominant desert shrub species in arid regions of northwest China, it playing an important role in the maintenance of the stability and continuity of desert ecosystem. The objectives of this study were to investigate the distribution characteristics of foliar δ13C value in R. soongorica, establish the correlations between foliar characteristics and environmental factors, and identify the major factor controlling the variations of foliar δ13C among different environments. Leaves of R. soongorica were collected from 21 natural populations in its major distribution area in northwestern China, across a range of mean annual precipitation from 27 to 328 mm, at altitudes from 394 to 1987 m above sea level, at latitudes from 36°N to 45°N and at longitudes from 81°E to 107°E. We measured the leaf nitrogen (LN), phosphorus (LP), potassium content (LK), leaf water content (LWC) and foliar δ13C in leaves of 407 individuals, and the soil physicochemical properties including nitrogen (SN), phosphorus (SP), soil organic matter (SOM), soil water contents (SWC) and total dissolved solids (TDS). Mean annual precipitation (MAP), mean annual temperature (MAT), evaporation, mean relative humidity (MRH) and duration of sunshine (DS), were collected from the Cold and Arid Environmental and Engineering Research Institute, Chinese Academy of Sciences. We observed that the foliar δ13C values increased significantly with the decreasing of MAP (r = -0.623, P = 0.003) and MRH(r = -0.702, P = 0.002), and decreased with decreasing DS and evaporation. No significant correlation with MAT was detected in δ13C values of R. soongorica. The correlations between foliar δ13C value and the soil factors demonstrated that the foliar δ13C values in R. soongorica significantly increased with the decreasing SWC (r = - 0.470, P = 0.037) and increasing TDS (r = 0.507, P = 0.022) in soil. There were no significant correlations between the foliar δ13C values and soil pH, total SN, SOM, total SP and available SP in soil. The main soil factors affecting δ13C values in the desert halophyte R. soongorica were SWC and TDS. Leaf δ13C values was significantly correlated with the contents of LK, LWC, and proline (P<0.001). Correlation with the contents of LK content was most profound (r=0.793), followed by that with LWC (r=0.786), indicating that the variation of leaf δ13C value could reflect the degree of drought stress and the variation in leaf δ13C values of R. soongorica were likely caused by stomatal conductance, rather than by nutrient-related changes in photosynthetic efficiency under extremely low available water conditions. The observed significant correlations between foliar δ13C values in R. soongorica and SWC and soil TDS reinforced that R. soongorica is a super-halophyte in terms of adaptive strategies to arid environments.
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Directory of Open Access Journals (Sweden)
Jintao Ge
2012-04-01
Full Text Available Calcium is an essential element and imparts significant structural rigidity to the plant cell walls, which provide the main mechanical support to the entire plant. In order to increase the mechanical strength of the inflorescence stems of herbaceous peony, the stems are treated with calcium chloride. The results shows that preharvest sprays with 4% (w/v calcium chloride three times after bud emergence are the best at strengthening “Da Fugui” peonies’ stems. Calcium sprays increased the concentrations of endogenous calcium, total pectin content as well as cell wall fractions in herbaceous peonies stems, and significantly increased the contents of them in the top segment. Correlation analysis showed that the breaking force of the top segment of peonies’ stems was positively correlated with the ratio of water insoluble pectin to water soluble pectin (R = 0.673 as well as lignin contents (R = 0.926 after calcium applications.
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Cómo explicar física cuántica con un gato zombi
Gonzalez Buron, Helena; Marimon Garrido, Oriol; Barrrecheguran Manero, Pablo; Luri Carrascoso, Xavier; Puerto Gimenez, Irene; Saenz de Cabezon Irigarai, Eduardo
2016-01-01
¿Sabías que el teletransporte es real? ¿Que a veces un electrón tiene probabilidades de atravesar una pared? ¿Que dos partículas pueden influenciarse mutuamente aunque estén a años luz de distancia? ¿Y que las partículas cuánticas son como Clark Kent y disimulan sus poderes cuando los científicos las están observando? En Cómo explicar la física cuántica con un gato zombi descubrirás que, aunque no lo parezca, la física cuántica está por todas partes en nuestra vida cotidiana. Y además aprenderás... ...¡los principios más locos y flipantes de la física cuántica! ...¡experimentos low cost que puedes hacer en tu casa! ...que los científicos están un poco pallá, ¿lo sabías? ...y que los gatos tampoco son muy normales que digamos...
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Investigation of Surface Enhanced Coherent Raman Scattering on Nano-patterned Insect Wings
Ujj, Laszlo; Lawhead, Carlos
2015-03-01
Many insect wings (cicadas, butterflies, mosquitos) poses nano-patterned surface structure. Characterization of surface morphology and chemical composition of insect wings is important to understand the extreme mechanical properties and the biophysical functionalities of the wings. We have measured the image of the membrane of a cicada's wing with the help of Scanning Electron Microscopy (SEM). The results confirm the existing periodic structure of the wing measured previously. In order to identify the chemical composition of the wing, we have deposited silver nanoparticles on it and applied Coherent anti-Stokes Raman Spectroscopy to measure the vibrational spectra of the molecules comprising the wing for the first time. The measured spectra are consistent with the original assumption that the wing membrane is composed of protein, wax, and chitin. The results of these studies can be used to measure other nano-patterned surfaces and to make artificial materials in the future. Authors grateful for financial support from the Department of Physics of the College of Sciences Engineering and Health of UWF and the Pall Corporation for SEM imaging.
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Evaluation of Alternative Filter Media for the Rotary Microfilter
Energy Technology Data Exchange (ETDEWEB)
Poirier, M. R.; Herman, D. T.; Bhave, R.
2011-11-09
The Savannah River Site is currently developing and testing several processes to treat high level radioactive liquid waste. Each of these processes has a solid-liquid separation process that limits its throughput. Savannah River National Laboratory researchers identified and tested the rotary microfilter as a technology to increase solid-liquid separation throughput. The authors believe the rotary microfilter throughput can be improved by using a better filter membrane. Previous testing showed that asymmetric filters composed of a ceramic membrane on top of a stainless steel support produced higher filter flux than 100% stainless steel symmetric filters in crossflow filter tests. Savannah River National Laboratory and Oak Ridge National Laboratory are working together to develop asymmetric ceramic ? stainless steel composite filters and asymmetric 100% stainless steel filters to improve the throughput of the rotary microfilter. The Oak Ridge National Laboratory Inorganic Membrane Group fabricated samples of alternative filter membranes. In addition, Savannah River National Laboratory obtained samples of filter membranes from Pall, Porvair, and SpinTek. They tested these samples in a static test cell with feed slurries containing monosodium titanate and simulated sludge.
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Plant uptake and transport of 241Am
International Nuclear Information System (INIS)
Wallace, A.; Romney, E.M.; Mueller, R.T. Sr.; soufi, S.M.
1981-01-01
We conducted several experiments with 241 Am to obtain a more complete understanding of how this transuranium element is absorbed and transported in plants. In a plant species (Tamarix pentandra Pall.) that has salt glands in the leaves excreting NaCl and other ions, 241 Am was not pumped through these glands. Cyanide, which forms complexes with any metals, when applied to a calcareous soil, greatly increased the transport of 241 Am into stems and leaves of bush bean plants. Radioactive cyanide ( 14 C) was also transported to leaves and stems. When radish was grown in both calcareous and noncalcareous soils, 241 Am appeared to be fixed on the peel so firmly that it was resistant to removal by HNO 3 washing. The chelating agent DTPA induced increased transport of 241 Am to leaves and into the fleshy roots of the radish. Data for Golden Cross hybrid corn grown in solution culture showed at least seven times as much 241 Am transport to the xylem exudatields are corrected by recovery of added tracers
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Interaction between Saikosaponin D, Paeoniflorin, and Human Serum Albumin.
Liang, Guo-Wu; Chen, Yi-Cun; Wang, Yi; Wang, Hong-Mei; Pan, Xiang-Yu; Chen, Pei-Hong; Niu, Qing-Xia
2018-01-27
Saikosaponin D (SSD) and paeoniflorin (PF) are the major active constituents of Bupleuri Radix and Paeonia lactiflora Pall , respectively, and have been widely used in China to treat liver and other diseases for many centuries. We explored the binding of SSD/PF to human serum albumin (HSA) by using fluorospectrophotometry, circular dichroism (CD) and molecular docking. Both SSD and PF produced a conformational change in HSA. Fluorescence quenching was accompanied by a blue shift in the fluorescence spectra. Co-binding of PF and SSD also induced quenching and a conformational change in HSA. The Stern-Volmer equation showed that quenching was dominated by static quenching. The binding constant for ternary interaction was below that for binary interaction. Site-competitive experiments demonstrated that SSD/PF bound to site I (subdomain IIA) and site II (subdomain IIIA) in HSA. Analysis of thermodynamic parameters indicated that hydrogen bonding and van der Waals forces were mostly responsible for the binary association. Also, there was energy transfer upon binary interaction. Molecular docking supported the experimental findings in conformation, binding sites and binding forces.
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Effects of Seedbed Density on Seedling Morphological Characteristics of four Broadleaved Species
Energy Technology Data Exchange (ETDEWEB)
Yucedag, C.; Gailing, O.
2012-11-01
The aim of this study was to investigate the effects of seedling spacing on morphological characteristics of one year-old Amygdalus communis L., Prunus avium L., Pyrus elaeagnifolia Pall. and Eriolobus trilobatus (Poiret) Roemer seedlings under nursery conditions. Seedlings were grown in completely randomized blocks with four replications. Seedbeds were 1.2 m wide with 5 rows each 20 cm apart. Within-row spacings were chosen as 4, 8 and 12 cm to analyze the effect of seedlings density on growth performance. Seedling spacing significantly affected root collar diameter, shoot height, tap root length and number of fine roots in A. communis and P. avium, but not in P. elaeagnifolia and E. tribolatus. Additionally wider seedling spacings resulted in larger seedlings in A. communis and P. avium. In conclusion, it would be beneficial to use wider seedling spacing in order to obtain better seedling growth in A. communis and P. avium. Larger seedlings could also provide significant advantages because of reduced cultural activities and an expected higher growth and survival rate. (Author) 27 refs.
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Evaluation of Alternative Filter Media for the Rotary Microfilter
International Nuclear Information System (INIS)
Poirier, M. R.; Herman, D. T.; Bhave, R.
2011-01-01
The Savannah River Site is currently developing and testing several processes to treat high level radioactive liquid waste. Each of these processes has a solid-liquid separation process that limits its throughput. Savannah River National Laboratory researchers identified and tested the rotary microfilter as a technology to increase solid-liquid separation throughput. The authors believe the rotary microfilter throughput can be improved by using a better filter membrane. Previous testing showed that asymmetric filters composed of a ceramic membrane on top of a stainless steel support produced higher filter flux than 100% stainless steel symmetric filters in crossflow filter tests. Savannah River National Laboratory and Oak Ridge National Laboratory are working together to develop asymmetric ceramic-stainless steel composite filters and asymmetric 100% stainless steel filters to improve the throughput of the rotary microfilter. The Oak Ridge National Laboratory Inorganic Membrane Group fabricated samples of alternative filter membranes. In addition, Savannah River National Laboratory obtained samples of filter membranes from Pall, Porvair, and SpinTek. They tested these samples in a static test cell with feed slurries containing monosodium titanate and simulated sludge
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Londres, ciudad única. Crítica de libros
Directory of Open Access Journals (Sweden)
Antón Capitel
2011-10-01
Full Text Available This book by Rasmunssen examines London with an extraordinary spatial expanse, character-ized by its free and original layout, made up of the union of different towns, and with an abun-dance of free spaces. It is an interesting analysis of the British capital, which examines small urban structures such as squares with a special emphasis, as well as their attractive vertical houses. The author of the review makes note of the passion shown by Rasmussen, which causes him to forget certain defects present within the city, such as the positive view upon the continuity of the layout found in the City. The author finds this last element to be something negative, which explains the unsatisfactory present situation. It also explains the unconvincing Victorian London, which the Danish professor ignores, as well as the inability to convert the river into a true city center after having relegated Southwark to the condition of a suburb.
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Two cases of neurogenic paralysis in medieval skeletal samples from Croatia.
Novak, Mario; Čavka, Mislav; Šlaus, Mario
2014-12-01
Osteological changes consistent with neurogenic paralysis were observed in one male and one female skeleton recovered from two Croatian medieval sites - Virje and Zadar. Both skeletons display limb asymmetry typical of neurogenic paralysis that occurs during the childhood. The male skeleton displays atrophy and shortening of the right arm and the right femur, while the female skeleton exhibits identical changes on the right arm and both legs. Additionally, both skeletons exhibit scoliotic changes of the spine, and the female skeleton also displays bilateral hip dysplasia. Differential diagnosis included disorders such as cerebral palsy, poliomyelitis, cerebrovascular accident, and Rasmussen's encephalitis. These are the first cases of neurogenic paralysis (cerebral palsy and/or paralytic poliomyelitis) identified in Croatian archeological series. The Virje skeleton is only the third case of hemiplegia identified from archeological contexts (first with spinal scoliosis), while the Zadar skeleton represents the first case of triplegia reported in the paleopathological literature. Copyright © 2014 Elsevier Inc. All rights reserved.
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Environmental impact of nuclear power stations
International Nuclear Information System (INIS)
Kellermann, O.; Balfanz, H.P.
1975-01-01
Following a comparative consideration of the present and future environmental impact by coal, oil, and nuclear power plants, the special risks connected with the use of the latter are dealt with. A distinction is made in considering the risk between public exposure, in the environment of a plant due to operational leakage and radiation exposure in the plant under normal operation and in the case of an accident. The accident risk consideration is the basis of the Rasmussen study where the different containment construction of german plants as well as the higher population density for sites in the FRG are considered. Evaluation parameters are given to quantify the risks and using this, the risks of various cases of impact of nuclear power plants are compared. The comparison shows that the risks of nuclear power plant operation according to the value in normal operation are comparable to those in the case of an accident. (ORU/LH) [de
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Advances in probabilistic risk analysis
International Nuclear Information System (INIS)
Hardung von Hardung, H.
1982-01-01
Probabilistic risk analysis can now look back upon almost a quarter century of intensive development. The early studies, whose methods and results are still referred to occasionally, however, only permitted rough estimates to be made of the probabilities of recognizable accident scenarios, failing to provide a method which could have served as a reference base in calculating the overall risk associated with nuclear power plants. The first truly solid attempt was the Rasmussen Study and, partly based on it, the German Risk Study. In those studies, probabilistic risk analysis has been given a much more precise basis. However, new methodologies have been developed in the meantime, which allow much more informative risk studies to be carried out. They have been found to be valuable tools for management decisions with respect to backfitting, reinforcement and risk limitation. Today they are mainly applied by specialized private consultants and have already found widespread application especially in the USA. (orig.) [de
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International Nuclear Information System (INIS)
Chakraborty, S.; Fuchs, H.; Gubler, R.; Landolt, J.; Miteff, L.
1985-01-01
Emergency planning around nuclear power plants should be based on a realistic assessment of their risk profile. Since the results of the Rasmussen study (WASH-1400) and later of the German risk study (Phase A) were not judged to be fully representative for NPP's in Switzerland, an investigation was started to transfer applicable US and German results to a Swiss 3-loop PWR (Goesgen) and to assess the impact of differences in plant design compared to Surry-1 and Biblis-B. The core melt probability for Goesgen was calculated to be more than a factor of ten smaller than for the US and German studies. This is mainly due to more redundancy/better separation (especially in the emergency feedwater) and to partial automation of cooldown after a small break. The results were instrumental in limiting the release categories to be used as reference cases for emergency planning. Further reduction of postulated accidental releases is expected from the current source term research
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DEFF Research Database (Denmark)
Rasmussen, Rie Romme; Qian, Yiting; Sloth, Jens Jørgen
2013-01-01
spectrometry (HG-AAS) detection. This approach was earlier developed for seafood samples (Rasmussen et al., Anal Bioanal Chem 403:2825–2834, 2012) and has in the present work been tailored for rice products and further optimised for a higher sample throughput and a lower detection limit. Water bath heating (90...... °C, 60 min) of samples with dilute HNO3 and H2O2 solubilised and oxidised all iAs to arsenate (AsV). Loading of buffered sample extracts (pH 6 ± 1) followed by selective elution of arsenate from a strong anion exchange SPE cartridge enabled the selective iAs quantification by HG-AAS, measuring total...... arsenic (As) in the SPE eluate. The in-house validation gave mean recoveries of 101–106 % for spiked rice samples and in two reference samples. The limit of detection was 0.02 mg kg−1, and repeatability and intra-laboratory reproducibility were less than 6 and 9 %, respectively. The SPE HG-AAS method...
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Generation of recombinant pestiviruses using a full genome amplification strategy
DEFF Research Database (Denmark)
Rasmussen, Thomas Bruun; Reimann, Ilona; Uttenthal, Åse
Aim Complete genome amplification of viral RNA provides a new tool for generation of modified pestiviruses. We have recently reported a full genome amplification strategy for direct recovery of infectious pestivirus (Rasmussen et al., 2008). This comprised rescue of BDV strain “Gifhorn” from a full......-length RT-PCR amplicon demonstrating that long RT-PCR can be used for direct generation of an infectious pestivirus. The strategy is not limited to amplification of BDV “Gifhorn”, but can be further utilized for amplification of a diverse selection of pestivirus strains and for the generation of modified...... was reverse transcribed to cDNA at 50C for 90 minutes using SuperScript III reverse transcriptase (Invitrogen). Full-length PCR amplification was performed using primers specific for the extreme 5’- and 3’-ends of the viral genomes. A T7 promoter was incorporated in the 5’-primers for direct in vitro...
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Higher molecular weight dissolved organic nitrogen turnover as affected by soil management history
DEFF Research Database (Denmark)
Lønne Enggrob, Kirsten
of different management histories on the turnover of high Mw DON. Further, we distinguished between several classes of high Mw DON, i.e., 1-10 kDa and >10 kDa. 3. Materials and methods With the use of micro-lysimeters, the turnover of triple-labeled (15N, 14C and 13C) high Mw DON was studied in a sandy soil......High molecular weight dissolved organic nitrogen turnover as affected by soil management history *Kirsten Lønne Enggrob,1 Lars Elsgaard,1 and Jim Rasmussen1 1Aarhus University, Dept. of Agroecology, Foulum, Denmark 1. Introduction Dissolved organic nitrogen (DON) play an important role in soil N...... are presented for 14CO2 evolution during 14 days of incubation. 4. Results and conclusion Results showed that the turnover rate of high Mw DON was dependent on both the Mw size of DON and on the soil liming history. Evidence showing where in the DON Mw sizes the bottleneck lies will be presented....
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Cognitive task analysis of nuclear power plant operators for man-machine interface design
International Nuclear Information System (INIS)
Itoh, J.I.; Yoshimura, S.; Ohtsuka, T.
1990-01-01
This paper aims to ascertain and further develop design guidelines for a man-machine interface compatible with plant operators' problem solving strategies. As the framework for this study, operator's information processing activities were modeled, based on J. Rasmussen's framework for cognitive task analysis. Two experiments were carried out. One was an experiment aimed at gaining an understanding of internal mechanisms involved in mistakes and slips which occurred in operators' responses to incidents and accidents. As a result of fifteen cases of operator performance analysis, sixty one human errors were identified. Further analysis of the errors showed that frequently occurring error mechanisms were absent-mindedness, lack of recognition of patterns in diagnosis and failed procedure formulation due to memory lapses. The other kind of experiment was carried out to identify the envelope of trajectories for the operator's search in the problem space consisting of the two dimensions of means-ends and whole-part relations while dealing with transients. Two cases of experimental sessions were conducted with the thinking-aloud method. From analyses based on verbal protocols, trajectories of operator's search were derived, covering from the whole plant level through the component level in the whole-part dimension and covering from the functional purpose level through the physical form level in the means-ends dimension. The findings obtained from these analyses serve as a basis for developing design guidelines for man-machine interfaces in control rooms of nuclear power plants
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Bicalho, Gustavo P; Braz, Leandro G; de Jesus, Larissa S B; Pedigone, Cesar M C; de Carvalho, Lídia R; Módolo, Norma S P; Braz, José R C
2014-10-01
An inhaled gas absolute humidity of 20 mg H2O·L is the value most considered as the threshold necessary for preventing the deleterious effects of dry gas on the epithelium of the airways during anesthesia. Because children have small minute ventilation, we hypothesized that the humidification of a circle breathing system is lower in children compared with adults. The Primus anesthesia workstation (Dräger Medical, Lübeck, Germany) has a built-in hotplate to heat the patient's exhaled gases. A heat and moisture exchanger (HME) is a device that can be used to further humidify and heat the inhaled gases during anesthesia. To evaluate the humidifying properties of this circle breathing system during pediatric anesthesia, we compared the temperature and humidity of inhaled gases under low or high fresh gas flow (FGF) conditions and with or without an HME. Forty children were randomly allocated into 4 groups according to the ventilation of their lungs by a circle breathing system in a Dräger Primus anesthesia workstation with low (1 L·min) or high (3 L·min) FGF without an HME (1L and 3L groups) or with an HME (Pall BB25FS, Pall Biomedical, East Hills, NY; HME1L and HME3L groups). The temperature and absolute humidity of inhaled gases were measured at 10, 20, 40, 60, and 80 minutes after connecting the patient to the breathing circuit. The mean inhaled gas temperature was higher in HME groups (HME1L: 30.3°C ± 1.1°C; HME3L: 29.3°C ± 1.2°C) compared with no-HME groups (1L: 27.0°C ± 1.2°C; 3L: 27.1°C ± 1.5°C; P [HME3L: 23 ± 2 mg H2O·L] > [1L: 17 ± 1 mg H2O·L] > [3L: 14 ± 1 mg H2O·L]; P pediatric circle breathing system, the use of neither high nor low FGF provides the minimum humidity level of the inhaled gases thought to reduce the risk of dehydration of airways. Insertion of an HME increases the humidity and temperature of the inhaled gases, bringing them closer to physiological values. The use of a low FGF enhances the HME efficiency and
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Rene, Eldon R; Jin, Yaomin; Veiga, María C; Kennes, Christian
2009-11-01
Biological treatment systems have emerged as cost-effective and eco-friendly techniques for treating waste gases from process industries at moderately high gas flow rates and low pollutant concentrations. In this study, we have assessed the performance of a two-stage bioreactor, namely a biotrickling filter packed with pall rings (BTF, 1st stage) and a perlite + pall ring mixed biofilter (BF, 2nd stage) operated in series, for handling a complex mixture of hydrogen sulphide (H2S), methanol (CH3OH) and alpha-pinene (C10H16). It has been reported that the presence of H2S can reduce the biofiltration efficiency of volatile organic compounds (VOCs) when both are present in the gas mixture. Hydrogen sulphide and methanol were removed in the first stage BTF, previously inoculated with H2S-adapted populations and a culture containing Candida boidinii, an acid-tolerant yeast, whereas, in the second stage, alpha-pinene was removed predominantly by the fungus Ophiostoma stenoceras. Experiments were conducted in five different phases, corresponding to inlet loading rates varying between 2.1 and 93.5 g m(-3) h(-1) for H2S, 55.3 and 1260.2 g m(-3) h(-1) for methanol, and 2.8 and 161.1 g m(-3) h(-1) for alpha-pinene. Empty bed residence times were varied between 83.4 and 10 s in the first stage and 146.4 and 17.6 s in the second stage. The BTF, working at a pH as low as 2.7 as a result of H2S degradation, removed most of the H2S and methanol but only very little alpha-pinene. On the other hand, the BF, at a pH around 6.0, removed the rest of the H2S, the non-degraded methanol and most of the alpha-pinene vapours. Attempts were originally made to remove the three pollutants in a single acidophilic bioreactor, but the Ophiostoma strain was hardly active at pH elimination capacities (ECs) reached by the two-stage bioreactor for individual pollutants were 894.4 g m(-3) h(-1) for methanol, 45.1 g m(-3) h(-1) for H2S and 138.1 g m(-3) h(-1) for alpha-pinene. The results from this
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Particulate hot gas stream cleanup technical issues
Energy Technology Data Exchange (ETDEWEB)
NONE
1998-09-01
This is the eleventh in a series of quarterly reports describing the activities performed under Contract No. DE-AC21-94MC31160. Analyses of Hot Gas Stream Cleanup (HGCU) ashes and descriptions of filter performance address aspects of filter operation that are apparently linked to the characteristics of the collected ash or the performance of the ceramic bed filter elements. Task 1 is designed to generate a data base of the key characteristics of ashes collected from operating advanced particle filters (APFS) and to relate these ash properties to the operation and performance of these filters. Task 2 concerns testing and failure analysis of ceramic filter elements. Under Task 1 during the past quarter, analyses were completed on samples obtained during a site visit to the Power Systems Development Facility (PSDF). Analyses are in progress on ash samples from the Advanced Particulate Filter (APF) at the Pressurized Fluidized-Bed Combustor (PFBC) that was in operation at Tidd and ash samples from the Pressurized Circulating Fluid Bed (PCFB) system located at Karhula, Finland. An additional analysis was performed on a particulate sample from the Transport Reactor Demonstration Unit (TRDU) located at the University of North Dakota Energy and Environmental Research Center. A manuscript and poster were prepared for presentation at the Advanced Coal-Based Power and Environmental Systems `97 Conference scheduled for July 22 - 24, 1997. A summary of recent project work covering the mechanisms responsible for ash deposit consolidation and ash bridging in APF`s collecting PFB ash was prepared and presented at FETC-MGN in early July. The material presented at that meeting is included in the manuscript prepared for the Contractor`s Conference and also in this report. Task 2 work during the past quarter included mechanical testing and microstructural examination of Schumacher FT20 and Pall 326 as- manufactured, after 540 hr in service at Karhula, and after 1166 hr in service at
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Magnetotelluric investigation of the Toender area, Denmark. ALTKUL project report part 2
Energy Technology Data Exchange (ETDEWEB)
Rasmussen, T.M.; Thorning, L. [GEUS, Copenhagen (Denmark); Pedersen, L.B.; Shan, C. [Uppsala Univ., Dept. of Earth Sciences, Uppsala (Sweden)
2012-10-15
Project ALTKUL was commissioned by DONG E and P A/S and Nordsoefonden; the Danish Energy Agency followed the project closely. The first part of the study has been reported in Rasmussen and Thorning (2012).The starting point of the study was a need for more knowledge on methods that could be used for hydrocarbon exploration in Danish onshore areas, as an alternative to seismic investigations, when these cannot be used for nature protecting reasons. DONG E and P A/S and Nordsoefonden approached GEUS, suggesting a study of seven different non-seismic methods. The Danish Energy Agency was interested in the subject and requested that an actual test of a method be carried out as a part of the project. The optimum choice for a field test was an electromagnetic experiment with a galvanic controlled source (Rasmussen and Thorning, 2012). However, due to organisational issues and a limited timeframe of the project, the final choice of method for the field test was settled on using the magnetotelluric method (MT). Though MT does not utilise galvanic controlled sources, and hence does not serve as a tool for direct hydrocarbon exploration, MT has been used in the past in relation with hydrocarbon exploration onshore and has recently gained considerable interest in China. A contract was entered with Uppsala University for some initial tests of the magnetotelluric (MT) method. The test was carried out August 2012 in an area around Toender, and is reported here as ALTKUL Project Report Part 2. In total 42 MT stations were measured in a 180 km{sup 2} area. The digital data are enclosed with the report and hereby released to the public. A 3D model of the electrical resistivity variations to a depth of 6 km constitutes, together with the actual measured data, the main results of part 2 of the ALTKUL project. The 3D model was derived from an unconstrained 3D inversion of the MT data. The MT data show that pronounced lateral resistivity variations exist at the depth of interest for
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DEFF Research Database (Denmark)
Rasmussen, Morten
, and observed that the glyco-peptides were identified correctly in 11/11 cases and the glycan moieties were annotated in 11/11 cases. Finally, glycan structures were proposed in 10/11 cases, all of which were in agreement with previously reported structures. As a stand-alone program, GLYCANthrope is a useful...
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Mao, Qing-Qiu; Xian, Yan-Fang; Ip, Siu-Po; Tsai, Sam-Hip; Che, Chun-Tao
2010-07-11
The root part of Paeonia lactiflora Pall., commonly known as peony, is a commonly used Chinese herb for the treatment of depression-like disorders. Previous studies in our laboratory have showed that total glycosides of peony (TGP) produced antidepressant-like action in various mouse models of behavioral despair. The present study aimed to investigate the mechanism(s) underlying the antidepressant-like action of TGP by measuring neurotrophins including brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) in non-stressed and chronic unpredictable mild stress (CUMS)-treated rats. TGP (80 or 160 mg/kg/day) was administered by oral gavage to the animals for 5 weeks. The results showed that CUMS caused depression-like behavior in rats, as indicated by the significant decreases in sucrose consumption and locomotor activity (assessed by open-field test). In addition, it was found that BDNF contents in the hippocampus and frontal cortex were significantly decreased in CUMS-treated rats. CUMS treatment also significantly decreased the level of NGF in the frontal cortex of the animals. Daily intragastric administration of TGP (80 or 160 mg/kg/day) during the five weeks of CUMS significantly suppressed behavioral and biochemical changes induced by CUMS. Treating non-stressed animals with TGP (160 mg/kg) for 5 weeks also significantly increased BDNF contents in the hippocampus and frontal cortex, and NGF contents in the frontal cortex. The results suggest that the antidepressant-like action of TGP is mediated, at least in part, by increasing the expression of BDNF and NGF in selective brain tissues. Copyright 2010 Elsevier B.V. All rights reserved.
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Wang, Kun; Wu, Yong-Gui; Su, Jing; Zhang, Jing-Jing; Zhang, Pei; Qi, Xiang-Ming
2012-01-01
Total glucosides of paeony (TGP) is the major active constituent of Paeonia lactiflora Pall., which has shown renoprotection in experimental diabetic nephropathy. Activation of Janus kinase/signal transducers and activators of transcription (JAK/STAT) is an important mechanism by which hyperglycemia contributes to renal damage. Macrophages also play an essential role in the pathogenesis of diabetic nephropathy. Herein, we investigated the ability of TGP to modulate JAK2/STAT3 activation and macrophage proliferation in rats with streptozotocin (STZ)-induced diabetes. TGP (50, 100, and 200 mg/kg) was administered orally once a day for eight weeks. Levels of p-JAK2 and p-STAT3 were determined by Western blot analysis. Immunohistochemistry and double immunohistochemistry were used to identify p-STAT3, ED-1, PCNA/ED-1, and p-STAT3/ED-1-positive (+) cells. The elevated 24-h urinary albumin excretion rate was markedly attenuated by treatment with 50, 100, and 200 mg/kg TGP. Western blot analysis showed that the significantly increased levels of p-JAK2, p-STAT3 proteins in the kidneys of diabetic rats were significantly inhibited by 50, 100, and 200 mg/kg TGP treatment. The marked accumulation and proliferation of macrophages in diabetic kidneys were significantly inhibited by TGP treatment. ED-1+/p-STAT3+ cells were significantly increased in the kidneys from the model group but were significantly inhibited by TGP treatment. These results show that TGP significantly inhibited diabetic nephropathy progression and suggest that these protective effects are associated with the ability of TGP to inhibit the JAK2/STAT3 pathway and macrophage proliferation and action.
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Styrene biofiltration in a trickle-bed reactor
Directory of Open Access Journals (Sweden)
V. Novak
2008-04-01
Full Text Available The biological treatment of styrene waste gas in a trickle-bed filter (TBF was investigated. The bioreactor consisted of a two-part glass cylinder (ID 150 mm filled with 25 mm polypropylene Pall rings serving as packing material. The bed height was 1m. Although the laboratory temperature was maintained at 22 ºC, the water temperature in the trickle-bed filter was slightly lower (about 18 ºC.The main aim of our study was to observe the effect of empty-bed residence time (EBRT on bioreactor performance at a constant pollutant concentration over an extended time period. The bioreactor was inoculated with a mixed microbial consortium isolated from a styrene-degrading biofilter that had been running for the previous two years. After three weeks of acclimation period, the bioreactor was loaded with styrene (100 mg.m-3. EBRT was in the range of 53 s to 13 s. A maximum elimination capacity (EC of 11.3 gC.m-3.h-1 was reached at an organic loading (OL rate of 18.6 gC.m-3.h-1.
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Identification of the human factors contributing to maintenance failures in a petroleum operation.
Antonovsky, Ari; Pollock, Clare; Straker, Leon
2014-03-01
This research aimed to identify the most frequently occurring human factors contributing to maintenance-related failures within a petroleum industry organization. Commonality between failures will assist in understanding reliability in maintenance processes, thereby preventing accidents in high-hazard domains. Methods exist for understanding the human factors contributing to accidents. Their application in a maintenance context mainly has been advanced in aviation and nuclear power. Maintenance in the petroleum industry provides a different context for investigating the role that human factors play in influencing outcomes. It is therefore worth investigating the contributing human factors to improve our understanding of both human factors in reliability and the factors specific to this domain. Detailed analyses were conducted of maintenance-related failures (N = 38) in a petroleum company using structured interviews with maintenance technicians. The interview structure was based on the Human Factor Investigation Tool (HFIT), which in turn was based on Rasmussen's model of human malfunction. A mean of 9.5 factors per incident was identified across the cases investigated.The three most frequent human factors contributing to the maintenance failures were found to be assumption (79% of cases), design and maintenance (71%), and communication (66%). HFIT proved to be a useful instrument for identifying the pattern of human factors that recurred most frequently in maintenance-related failures. The high frequency of failures attributed to assumptions and communication demonstrated the importance of problem-solving abilities and organizational communication in a domain where maintenance personnel have a high degree of autonomy and a wide geographical distribution.
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Meshkati, Najmedin; Tabibzadeh, Maryam; Farshid, Ali; Rahimi, Mansour; Alhanaee, Ghena
2016-02-01
The aim of this study is to identify the interdependencies of human and organizational subsystems of multiple complex, safety-sensitive technological systems and their interoperability in the context of sustainability and resilience of an ecosystem. Recent technological disasters with severe environmental impact are attributed to human factors and safety culture causes. One of the most populous and environmentally sensitive regions in the world, the (Persian) Gulf, is on the confluence of an exponentially growing number of two industries--nuclear power and seawater desalination plants--that is changing its land- and seascape. Building upon Rasmussen's model, a macrosystem integrative framework, based on the broader context of human factors, is developed, which can be considered in this context as a "meta-ergonomics" paradigm, for the analysis of interactions, design of interoperability, and integration of decisions of major actors whose actions can affect safety and sustainability of the focused industries during routine and nonroutine (emergency) operations. Based on the emerging realities in the Gulf region, it is concluded that without such systematic approach toward addressing the interdependencies of water and energy sources, sustainability will be only a short-lived dream and prosperity will be a disappearing mirage for millions of people in the region. This multilayered framework for the integration of people, technology, and ecosystem--which has been applied to the (Persian) Gulf--offers a viable and vital approach to the design and operation of large-scale complex systems wherever the nexus of water, energy, and food sources are concerned, such as the Black Sea. © 2016, Human Factors and Ergonomics Society.
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DEFF Research Database (Denmark)
Rasmussen, Henrik Koblitz; Arlø, Uffe Rolf; Kjær, Erik Michael
2001-01-01
The development of microstructures is a growing industry. The technological development is working towards smaller products and structures, opening up new areas for exploitation. In the following the design and the fabrication of the microstructures will be presented....
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A new one-man submarine is tested as vehicle for solid rocket booster retrieval
2000-01-01
- The one-man submarine known as DeepWorker 2000 is tested in Atlantic waters near Cape Canaveral, Fla. Nearby are divers; inside the sub is the pilot, Anker Rasmussen. The sub is being tested on its ability to duplicate the sometimes hazardous job United Space Alliance (USA) divers perform to recover the expended boosters in the ocean after a launch. The boosters splash down in an impact area about 140 miles east of Jacksonville and after recovery are towed back to KSC for refurbishment by the specially rigged recovery ships. DeepWorker 2000 will be used in a demonstration during retrieval operations after the upcoming STS-101 launch. The submarine pilot will demonstrate capabilities to cut tangled parachute riser lines using a manipulator arm and attach a Diver Operator Plug to extract water and provide flotation for the booster. DeepWorker 2000 was built by Nuytco Research Ltd., North Vancouver, British Columbia. It is 8.25 feet long, 5.75 feet high, and weighs 3,800 pounds. USA is a prime contractor to NASA for the Space Shuttle program.
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Musikplanlægning i Danmarks Radio - et interview med to musikansvarlige
Directory of Open Access Journals (Sweden)
Henrik Dahl
1992-08-01
Full Text Available Danmarks Radio er en væsentlig faktor i det danske musikliv i dag. Musikindustrien får sine potentielle hits præsenteret og den levende musik kommer ud via transmissionsvognene. DR har tre orkestre og 2 kor og producerer selv musik af høj kvalitet. Der er tale om et kredsløb - eller fødekæde om man vil - hvor radioen indgår som distributionskanal, udstillingsvindue og formidler af både musik og diskussionen omkring den. Hvordan forvalter Danmarks Radio sin musik- og kulturpolitiske funktion? Hvem bestemmer hvad der skal spilles i radioen? Er det medarbejderne, programcheferne eller radioledelsen? Og hvem tager man hensyn til? Lyttertal? Den offentlige mening? - I dette dobbeltinterview med to chefer, Bent-Erik Rasmussen og Torben Bille, der er ansvarlige for musikken på henholdsvis P2 (undtagen Danmarkskanalen og P3, prøver vi at belyse de overvejelser der ligger bag den seneste kanalomlægning og den daglige styring af danskernes musikoplevelser.
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Energy Technology Data Exchange (ETDEWEB)
NONE
1975-10-01
The Reactor Safety Study was sponsored by the U. S. Atomic Energy Commission to estimate the public risks that could be involved in potential accidents in commercial nuclear power plants of the type now in use. It was performed under the independent direction of Professor Norman C. Rasmussen of the Massachusetts Institute of Technology. The risks had to be estimated, rather than measured, because although there are about 50 such plants now operating, there have been no nuclear accidents to date resulting in significant releases of radioactivity in U.S. commercial nuclear power plants. The objective of the study was to make a realistic estimate of these risks and, to provide perspective, to compare them with non-nuclear risks to which our society and its individuals are already exposed. This information may be of help in determining the future reliance by society on nuclear power as a source of electricity. The results from this study suggest that the risks to the public from potential accidents in nuclear power plants are comparatively small.
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Plant operator performance evaluation system
International Nuclear Information System (INIS)
Ujita, Hiroshi; Fukuda, Mitsuko; Kubota, Ryuji.
1989-01-01
A plant operator performance evaluation system to analyze plant operation records during accident training and to identify and classify operator errors has been developed for the purpose of supporting realization of a training and education system for plant operators. A knowledge engineering technique was applied to evaluation of operator behavior by both even-based and symptom-based procedures, in various situations including event transition due to multiple failures or operational errors. The system classifies the identified errors as to their single and double types based on Swain's error classification and the error levels reflecting Rasmussen's cognitive level, and it also evaluates the effect of errors on plant state and then classifies error influence, using 'knowledge for phenomena and operations', as represented by frames. It has additional functions for analysis of error statistics and knowledge acquisition support of 'knowledge for operations'. The system was applied to a training analysis for a scram event in a BWR plant, and its error analysis function was confirmed to be effective by operational experts. (author)
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On the characterization of risk
International Nuclear Information System (INIS)
Tzur, Y.
1980-01-01
The concept of risk is associated with the concepts of event, harmful consequence, and probability. Initiating events and their possible developments, together with their associated probabilities, induce a probability space on the space of consequences. The risk is defined as a probability density function (or distribution) on the space of harmful consequences. The risks involved in nuclear power plants are taken as an example. Possible presentations of the risk (e.g. radiation-dose space and health-effects space) are discussed and the relationship between them is analysed. The relationship of some presentations in common use (such as the presentation of the risk in the Rasmussen report) to the above definition of the risk is also discussed. Some of the implications of the definition are explored further and the different receptors of risk, social and personal risks, and the possibility (or impossibility) of comparing risks are discussed. Ways of refining the description of the risk in risk assessments are outlined as an application of the definition. It is argued that personal risk, social risk, and correlations between consequences are necessary. (author)
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Spoken language outcomes after hemispherectomy: factoring in etiology.
Curtiss, S; de Bode, S; Mathern, G W
2001-12-01
We analyzed postsurgery linguistic outcomes of 43 hemispherectomy patients operated on at UCLA. We rated spoken language (Spoken Language Rank, SLR) on a scale from 0 (no language) to 6 (mature grammar) and examined the effects of side of resection/damage, age at surgery/seizure onset, seizure control postsurgery, and etiology on language development. Etiology was defined as developmental (cortical dysplasia and prenatal stroke) and acquired pathology (Rasmussen's encephalitis and postnatal stroke). We found that clinical variables were predictive of language outcomes only when they were considered within distinct etiology groups. Specifically, children with developmental etiologies had lower SLRs than those with acquired pathologies (p =.0006); age factors correlated positively with higher SLRs only for children with acquired etiologies (p =.0006); right-sided resections led to higher SLRs only for the acquired group (p =.0008); and postsurgery seizure control correlated positively with SLR only for those with developmental etiologies (p =.0047). We argue that the variables considered are not independent predictors of spoken language outcome posthemispherectomy but should be viewed instead as characteristics of etiology. Copyright 2001 Elsevier Science.
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Energy Technology Data Exchange (ETDEWEB)
Silla, I; Gamero, N
2011-12-27
Previous research has emphasized the need to consider the social dimension featuring organizations in order to maximize organizational efficiency (Rasmussen, 1997). In the road transport sector, previous research has focused on the relationship between human factor, stress, fatigue, and other relevant issues, and professional drivers health and safety (p.e., De Croon et al, 2004). However, research on relevant organizational factors is scarce. This study aims to examine the association between leadership and supportive climate, and employees health and safety. Moreover, the impact of stress (time pressure) was also examined because previous research has stressed its importance. This study used a sample of 486 employees from 35 different Spanish companies pertaining to the road transport sector. Findings showed time pressure to be negatively associated to employees health, job satisfaction and satisfaction with safety. Additionally, leadership was positively associated employees health, job satisfaction and satisfaction with safety. Finally, co-workers and supervisors supportive climate was positively associated with job satisfaction and negatively associated to illness. These findings have relevant practical implications for the competitiveness of road transport companies. (Author) 21 refs.
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International Nuclear Information System (INIS)
1975-10-01
The Reactor Safety Study was sponsored by the U. S. Atomic Energy Commission to estimate the public risks that could be involved in potential accidents in commercial nuclear power plants of the type now in use. It was performed under the independent direction of Professor Norman C. Rasmussen of the Massachusetts Institute of Technology. The risks had to be estimated, rather than measured, because although there are about 50 such plants now operating, there have been no nuclear accidents to date resulting in significant releases of radioactivity in U.S. commercial nuclear power plants. The objective of the study was to make a realistic estimate of these risks and, to provide perspective, to compare them with non-nuclear risks to which our society and its individuals are already exposed. This information may be of help in determining the future reliance by society on nuclear power as a source of electricity. The results from this study suggest that the risks to the public from potential accidents in nuclear power plants are comparatively small
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DEFF Research Database (Denmark)
Fisker, Anna Marie; Hermanssdottir, Sunna; Rasmussen, Mai
Meals in day-care centers have for many children a crucial influence on the total experience of the stay. Research already suggests, that the meal situation should not be delimited to the nutritional meaning only, but has to be seen in a broad holistic perspective (Rasmussen and Smidt, 2001). In ...... and pedagogy can create solutions that positively affect eating habits and food preferences among children, and furthermore if this aspect can strengthen innovation in the food sector and create valuable solutions related to health benefits among children.......). In our research, regarding children’s eating habits and food preferences, we collaborated interdisciplinary, working holistically, involving appropriate disciplines, where knowledge from different fields was involved. The importance of working interdisciplinary in food innovation can be seen......, that affect children’s eating habits and food preferences. In order to make evidence in the field, an interdisciplinary team consisting of food specialists, designers, engineers, architects and pedagogues, created a carrot pavilion and appurtenant carrot activities. The aim was to influence the children...
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Transmutation: a decade of revival issues, relevant experiments and perspectives
International Nuclear Information System (INIS)
Salvatores, M.
2001-01-01
For more than a decade, transmutation studies have been again a topic of wide interest and have triggered numerous international activities, like bilateral/multilateral collaborations, information exchanges, state-of-the-art reports, conferences, but also some co-ordinated programmes and experiments. It is legitimate to ask at this point, whether transmutation studies are still 'fashionable' and why; what is known, what has been done and what should be done. Since the motivations of national programmes are often different, due to a different context, we will take for granted that transmutation is generally seen as an option for the back-end of the fuel cycle in order to reduce the burden of potential geological storages of radioactive wastes (whatever their nature). Finally, we also acknowledge the fact that some highly respected scientists have at several occasions during this decade expressed their doubts about the value of the transmutation option. A typical example is the position expressed by Pigford and Rasmussen, reporting the results of a study for the US National Research Council. (author)
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Risk Assessment Review Group report to the U.S. Nuclear Regulatory Commission
International Nuclear Information System (INIS)
Lewis, H.W.; Budnitz, R.J.; Kouts, H.J.C.; Loewenstein, W.B.; Rowe, W.D.; von Hippel, F.; Zachariasen, F.
1978-09-01
The Risk Assessment Review Group was organized by the U.S. Nuclear Regulatory Commission on July 1, 1977, with four elements to its charter: clarify the achievements and limitations of WASH-1400, the ''Rasmussen Report''; assess the peer comments thereon, and responses to those comments; study the present state of such risk assessment methodology; and recommend to the Commission how (and whether) such methodology can be used in the regulatory and licensing process. Areas of study include: risk assessment methodologies; statistical issues; completeness; the data base; and the WASH-1400 assessment of the damage to human health from radiation after a postulated accident. Specific items discussed include: Browns Ferry; common cause failure; human factors; format and scrutability; the peer review process; earthquakes; risk perception; allegations by UCS concerning WASH-1400 treatment of quality assurance and quality control; current role of probabilistic methods in the regulatory process; acts of violence; ATWS; influence of design defects in quality assurance failures; and calculation of population doses from given releases of radionuclides
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Nuclear structure research. Annual progress report
International Nuclear Information System (INIS)
Wood, J.L.
1996-01-01
The most significant development this year has been the realization that EO transition strength is a fundamental manifestation of nuclear mean-square charge radius differences. Thus, EO transitions provide a fundamental signature for shape coexistence in nuclei. In this sense, EO transitions are second only to E2 transitions for signaling (quadrupole) shapes in nuclei and do so when shape differences occur. A major effort has been devoted to the review of EO transitions in nuclei. Experiments have been carried out or are scheduled at: ATLAS/FMA (α decay of very neutron-deficient Bi isotopes); MSU/NSCL (β decay of 56 Cu); and HRIBF/RMS (commissioning of tape collector, internal conversion/internal-pair spectrometer; β decay of 58 Cu). A considerable effort has been devoted to planning the nuclear structure physics that will be pursued using HRIBF. Theoretical investigations have continued in collaboration with Prof. K. Heyde, Prof. D.J. Rowe, Prof. J.O. Rasmussen, and Prof. P.B. Semmes. These studies focus on shape coexistence and particle-core coupling
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Zulewska, Justyna; Barbano, David M
2013-04-01
Raw milk (approximately 1,800 kg) was separated at 4°C, pasteurized (at 72°C for 16s), and split into 2 batches. One batch (620 kg) was microfiltered (MF) using pilot-scale ceramic uniform transmembrane pressure Membralox membranes (model EP1940GL0.1 μA, 0.1-μm alumina; Pall Corp., East Hills, NY) to produce retentate and permeate. The permeate from the MF uniform transmembrane pressure was casein-free skim milk (CFSM). The CFSM was MF using polymeric spiral-wound (SW) membranes (model FG7838-OS0x-S, 0.3 μm; Parker-Hannifin Corp., Process Advanced Filtration Division, Tell City, IN) at a concentration factor of 3× and temperature of 50°C. Following the processing of CFSM, the second batch of skim milk (1,105 kg) was processed using the same polymeric membranes to determine how casein content in the feed material for MF with polymeric membranes affects the performance of the system. There was little resistance to passage of milk serum proteins (SP) through a 0.3-μm polyvinylidene fluoride (PVDF) SW membrane at 50°C and no detectable increase in hydraulic resistance of the membrane when processing CFSM. Therefore, milk SP contributed little, if any, to fouling of the PVDF membrane. In contrast, when processing skim milk containing a normal concentration of casein, the flux was much lower than when processing CFSM (17.2 vs. 80.2 kg/m(2) per hour, respectively) and the removal of SP from skim milk with a single-pass 3× bleed-and-feed MF system was also much lower than from CFSM (35.2 vs. 59.5% removal, respectively). Thus, when processing skim milk with a PVDF SW membrane, casein was the major protein foulant that increased hydraulic resistance and reduced passage of SP through the membrane. Copyright © 2013 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.
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Energy Technology Data Exchange (ETDEWEB)
Doersch, C.; Ohlendorf, J.H.; Gebauer, I.; Mueller, D.H. [Bremer Institut fuer Konstruktionstechnik, Universitaet Bremen (Germany); Weigel, L. [Abeking Rasmussen Rotec GmbH and Co. KG, Lemwerder (Germany)
2007-11-15
Rotor blades of wind turbines are mainly manufactured from fibre reinforced plastics. These materials show an excellent performance concering the ratio of stiffness and weight. Basically the composite material of rotor blades is made out of glass fibres and thermosetting material. But growing technological and economical requirements to rotor blades by off-shore-application, in particular through increasing rotor blade diameter, have to meet successful. Although reduction of processing time and increased quality of rotor blades play a major role. To achieve the increasing requirements of the rotor blade manufacturing the Bremen Institute for Engineering Design and the rotor blade manufacturer Abeking and Rasmussen Rotec GmbH are working together on the handling and manufacturing of textile preforms. Preforms are made out of stacked and bonded dry textile layers and deposited in the mould as one textile part. Preforming allows the parallel processing of some manufacturing steps. This shows great advantages in the production of fibre reinforced plastics because of the long curing time of the resin component. This parallel processing is required to reach the aim of decreased overall cycle time. This essay is focussing on the handling of textiles and the textile preforming. Summarised aspects of quality management and economics in textile preforming will be discussed with the aim of automising the preforming process. (Abstract Copyright [2007], Wiley Periodicals, Inc.) [German] Rotorblaetter von Windenergieanlagen werden aufgrund des guten Verhaeltnisses von Steifigkeit und Gewicht zu grossen Teilen aus Faserverbundwerkstoffen gefertigt. Dabei kommen hauptsaechlich Glasfasern (GF) als verstaerkendes Material sowie duroplastische Harze als Matrix zur Anwendung. Um die wachsenden Herausforderungen des Offshore-Einsatzes von Windenergieanlagen, insbesondere die steigende Rotorblattgroesse, technisch und wirtschaftlich erfolgreich bewaeltigen zu koennen, wird die
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Zhang, Yuchi; Liu, Chunming; Li, Jing; Qi, Yanjuan; Li, Yuchun; Li, Sainan
2015-09-01
A new method for the extraction of medicinal herbs termed ultrasonic-assisted dynamic extraction (UADE) was designed and evaluated. This technique was coupled with counter-current chromatography (CCC) and centrifugal partition chromatography (CPC) and then applied to the continuous extraction and online isolation of chemical constituents from Paeonia lactiflora Pall (white peony) roots. The mechanical parameters, including the pitch and diameter of the shaft, were optimized by means of mathematical modeling. Furthermore, the configuration and mechanism of online UADE coupled with CCC and CPC were elaborated. The stationary phases of the two-phase solvent systems from CCC and CPC were utilized as the UADE solution. The extraction solution was pumped into the sample loop and then introduced into the CCC column; the target compounds were eluted with the lower aqueous phase of the two-phase solvent system. During the CCC separation, the extraction solution was continuously fed in the sample loop by turning the ten-port valve; the extraction solution was then pumped into the CPC column and eluted by the mobile phase of the two-phase solvent system mentioned above. When the first cycle of the UADE/CCC/CPC was completed, the second cycle experiment could be carried out, and so on. Four target compounds (albiflorin, benzoylpaeoniflorin, paeoniflorin, and galloylpaeoniflorin) with purities above 94.96% were successfully extracted and isolated online using the two-phase solvent system comprising ethyl acetate-n-butanol-ethanol-water (1:3.5:2:4.5, v/v/v/v). Compared with conventional extraction methods, the instrumental setup of the present method offers the advantages of automation and systematic extraction and isolation of natural products. Crown Copyright © 2015. Published by Elsevier B.V. All rights reserved.
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The effects of refraction on transit transmission spectroscopy: application to Earth-like exoplanets
Energy Technology Data Exchange (ETDEWEB)
Misra, Amit; Meadows, Victoria [Astronomy Department, University of Washington, Box 351580, Seattle, WA 98195 (United States); Crisp, Dave, E-mail: amit0@astro.washington.edu [NAI Virtual Planetary Laboratory, Seattle, WA (United States)
2014-09-01
We quantify the effects of refraction in transit transmission spectroscopy on spectral absorption features and on temporal variations that could be used to obtain altitude-dependent spectra for planets orbiting stars of different stellar types. We validate our model against altitude-dependent transmission spectra of the Earth from ATMOS and against lunar eclipse spectra from Pallé et al. We perform detectability studies to show the potential effects of refraction on hypothetical observations of Earth analogs with the James Webb Space Telescope NIRSPEC. Due to refraction, there will be a maximum tangent pressure level that can be probed during transit for each given planet-star system. We show that because of refraction, for an Earth-analog planet orbiting in the habitable zone of a Sun-like star only the top 0.3 bars of the atmosphere can be probed, leading to a decrease in the signal-to-noise ratio (S/N) of absorption features by 60%, while for an Earth-analog planet orbiting in the habitable zone of an M5V star it is possible to probe almost the entire atmosphere with minimal decreases in S/N. We also show that refraction can result in temporal variations in the transit transmission spectrum which may provide a way to obtain altitude-dependent spectra of exoplanet atmospheres. Additionally, the variations prior to ingress and subsequent to egress provide a way to probe pressures greater than the maximum tangent pressure that can be probed during transit. Therefore, probing the maximum range of atmospheric altitudes, and in particular the near-surface environment of an Earth-analog exoplanet, will require looking at out-of-transit refracted light in addition to the in-transit spectrum.
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The effects of refraction on transit transmission spectroscopy: application to Earth-like exoplanets
International Nuclear Information System (INIS)
Misra, Amit; Meadows, Victoria; Crisp, Dave
2014-01-01
We quantify the effects of refraction in transit transmission spectroscopy on spectral absorption features and on temporal variations that could be used to obtain altitude-dependent spectra for planets orbiting stars of different stellar types. We validate our model against altitude-dependent transmission spectra of the Earth from ATMOS and against lunar eclipse spectra from Pallé et al. We perform detectability studies to show the potential effects of refraction on hypothetical observations of Earth analogs with the James Webb Space Telescope NIRSPEC. Due to refraction, there will be a maximum tangent pressure level that can be probed during transit for each given planet-star system. We show that because of refraction, for an Earth-analog planet orbiting in the habitable zone of a Sun-like star only the top 0.3 bars of the atmosphere can be probed, leading to a decrease in the signal-to-noise ratio (S/N) of absorption features by 60%, while for an Earth-analog planet orbiting in the habitable zone of an M5V star it is possible to probe almost the entire atmosphere with minimal decreases in S/N. We also show that refraction can result in temporal variations in the transit transmission spectrum which may provide a way to obtain altitude-dependent spectra of exoplanet atmospheres. Additionally, the variations prior to ingress and subsequent to egress provide a way to probe pressures greater than the maximum tangent pressure that can be probed during transit. Therefore, probing the maximum range of atmospheric altitudes, and in particular the near-surface environment of an Earth-analog exoplanet, will require looking at out-of-transit refracted light in addition to the in-transit spectrum.
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Huang, Xue-Tao; Wang, Bin; Zhang, Wen-Hua; Peng, Man-Qiang; Lin, Ding
2018-01-01
Total glucosides of paeony (TGP) are active components extracted from the roots of Paeonia lactiflora Pall. In this study, we investigated the role and mechanisms of TGP in experimental autoimmune uveitis (EAU) model of mice. The C57BL/6 mice were randomly divided into three groups: sham group, EAU-control group, and EAU-TGP group. Clinical score of images of the eye fundus were taken on 7, 14, 21, and 28 days after induction of EAU. The concentrations of proinflammatory cytokines in intraocular fluid were measured at 14 days after EAU induction with the use of a multiplex assay system. Flow cytometry was used to analyze the frequency of CD4+, CD8+, interferon-gamma (IFN-γ), and CD4+/CD8+ ratio in spleen and lymph nodes. Western blotting was used to measure expressions of mitogen-activated protein kinase (MAPK) pathway-related proteins in retina. Clinical scores for uveitis were lower in TGP-treated EAU mice than those without TGP treatment. Importantly, the concentrations of cytokines induced by T-helper 1 (Th1) and T-helper 2 (Th2) cells in intraocular fluid were reduced in EAU mice treated with TGP. Furthermore, the frequency of CD4+, IFN-γ, and CD4+/CD8+ ratio was decreased and the frequency of CD8+ was increased in spleen and lymph nodes of mice treated with TGP. The anti-inflammatory effects of TGP were mediated by inhibiting the MAPK signaling pathways. Our results showed that TGP suppressed uveitis in mice via the inhibition of Th1 and Th2 cell function. Thus, TGP may be a promising therapeutic strategy for uveitis, as well as other ocular inflammatory diseases.
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DEFF Research Database (Denmark)
Rasmussen, Henrik Koblitz; Christensen, Jens H.; Kjær, Erik Michael
1999-01-01
In order to characterize materials using a simple and relative inexpensive method, the bubble inflation technique was modified. A polymer plate is clamped between a Teflon coated plate and a heated cylinder. By applying air through the heating plate the polymer membrane deforms into the cylinder...
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Panigaj, Lubomír; Zach, Peter; Honěk, Alois; Nedvěd, Oldřich; Kulfan, Ján; Martinková, Zdenka; Selyemová, Diana; Viglášová, Sandra; Roy, Helen E
2014-01-01
The harlequin ladybird beetle Harmonia axyridis (Coleoptera, Coccinellidae) has invaded and established in Slovakia. Following unintentional introduction in 2008, the spread of the alien coccinellid was very fast. By the end of 2009, it was recorded across the whole country, and by the end of 2012 it was widely distributed and common in various habitats, particularly gardens, orchards and urban areas, where it was most frequent on trees. The rate of eastward spread was approximately 200 km year(-1), similar to the overall rate of spread in Europe. Between 2008 and 2012, the coccinellid was recorded in a total of 153 localities, in altitudes ranging from 98 to 1,250 m. Most records of this species were made in lowlands, hilly areas and valleys separating mountain ridges. However, it was only rarely documented in areas above 700 m a.s.l. The non-melanic colour form (f. succinea) was dominant along a longitudinal transect including eight urban areas across Slovakia, with the frequency of melanic forms (f. spectabilis and f. conspicua together) between 6.3 and 19.2% and a median equal to 10.5%. The invasion history and distribution of H. axyridis in Slovakia are discussed with regard to the time sequence of records, rate of spread, altitudinal distribution, anthropogenic dispersal, effective recording, proportion of melanic forms and other relevant aspects associated with the spread of this successful invader.
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Czech Academy of Sciences Publication Activity Database
Panigaj, L.; Zach, P.; Honěk, A.; Nedvěd, Oldřich; Kulfan, J.; Martínková, Z.; Selyemová, D.; Viglášová, S.; Roy, H. E.
-, č. 412 (2014), s. 89-102 ISSN 1313-2989 Grant - others:Slovak Research and Development Agency(SK) APVV 0200/11; Grant Agency of Ministry of Education and SAS(SK) 1/1025/12; Grant Agency of Ministry of Education and SAS(SK) 2/0035/13; Grant Agency of Ministry of Education and SAS(SK) 2/0157/11; Mze ČR(CZ) QH82047; MŠMT ČR(CZ) 7AMB12SK141; EU COST(CZ) TD1209 Program:FA Institutional support: RVO:60077344 Keywords : alien * altitude * colour morphs Subject RIV: EH - Ecology, Behaviour Impact factor: 0.933, year: 2014 http://europepmc.org/articles/PMC4042697;jsessionid=aEQnuIZkqJpBc2xpenqy.0
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Directory of Open Access Journals (Sweden)
Ľubomír Panigaj
2014-05-01
Full Text Available The harlequin ladybird beetle Harmonia axyridis (Coleoptera, Coccinellidae has invaded and established in Slovakia. Following unintentional introduction in 2008, the spread of the alien coccinellid was very fast. By the end of 2009, it was recorded across the whole country, and by the end of 2012 it was widely distributed and common in various habitats, particularly gardens, orchards and urban areas, where it was most frequent on trees. The rate of eastward spread was approximately 200 km year-1, similar to the overall rate of spread in Europe. Between 2008 and 2012, the coccinellid was recorded in a total of 153 localities, in altitudes ranging from 98 to 1,250 m. Most records of this species were made in lowlands, hilly areas and valleys separating mountain ridges. However, it was only rarely documented in areas above 700 m a.s.l. The non-melanic colour form (f. succinea was dominant along alongitudinal transect including eight urban areas across Slovakia, with the frequency of melanic forms (f. spectabilis and f. conspicua together between 6.3 and 19.2% and a median equal to 10.5%. The invasion history and distribution of H. axyridis in Slovakia are discussed with regard to the time sequence of records, rate of spread, altitudinal distribution, anthropogenic dispersal, effective recording, proportion of melanic forms and other relevant aspects associated with the spread of this successful invader.
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Directory of Open Access Journals (Sweden)
Rajni Kant
2016-05-01
Full Text Available Glycine N-methyltransferase (GNMT expression is vastly downregulated in hepatocellular carcinomas (HCC. High rates of GNMT knockout mice developed HCC, while overexpression of GNMT prevented aflatoxin-induced carcinogenicity and inhibited liver cancer cell proliferation. Therefore, in this study, we aimed for the identification of a GNMT inducer for HCC therapy. We established a GNMT promoter-driven luciferase reporter assay as a drug screening platform. Screening of 324 pure compounds and 480 crude extracts from Chinese medicinal herbs resulted in the identification of Paeonia lactiflora Pall (PL extract and the active component 1,2,3,4,6-penta-O-galloyl-β-d-glucopyranoside (PGG as a GNMT inducer. Purified PL extract and PGG induced GNMT mRNA and protein expression in Huh7 human hepatoma cells and in xenograft tumors. PGG and PL extract had potent anti-HCC effects both in vitro and in vivo. Furthermore, PGG treatment induced apoptosis in Huh7 cells. Moreover, PGG treatment sensitized Huh7 cells to sorafenib treatment. Therefore, these results indicated that identifying a GNMT enhancer using the GNMT promoter-based assay might be a useful approach to find drugs for HCC. These data also suggested that PGG has therapeutic potential for the treatment of HCC.
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Directory of Open Access Journals (Sweden)
Wang Dong-sheng
2017-01-01
Full Text Available Actinomycetes are important producers of novel bioactive compounds. New sources need to be explored for isolating previously unknown bioactive compound-producing actinomycetes. Here we evaluated the potential of bark as a natural source of novel bioactive actinomycete species. Bark samples were collected from nine tree species at different elevations (1600-3400 ma.s.l. on Qin Mountain, Shaanxi Province, China. Actinomycetes were cultivated, enumerated and isolated using serial dilution and spread-plate techniques. The antimicrobial activity of actinomycete isolates was analyzed using an agar block method against 15 typical bacterial and fungal species and plant pathogens. The dominant isolates were identified by 16S rRNA-based sequence analysis. Results showed that actinomycete counts in bark samples of Quercus liaotungensis Koidz. was the highest among all trees species tested. The numbers of actinomycete species in bark samples were highest in Q. aliena var. acutiserrata and Spiraea alpina Pall. Antagonistic activity wasdetected in approximately 54% of the actinomycete isolates. Of these, 20 isolates (25% showed broad-spectrum antagonistic activity against ≥5 of the microorganisms tested. In conclusion, the bark on coniferous and broadleaf trees possesses a high diversity of actinomycetes and serves as a natural source of bioactive compound-producing actinomycetes.
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Arsenic deposition in tissues of the European hare (Lepus europaeus
Directory of Open Access Journals (Sweden)
Karel Bukovjan
2016-01-01
Full Text Available The work deals with arsenic deposition in individual biological matrices of the European hare (Lepus europaeus Pall.. The aim of this work was to evaluate the arsenic deposition in biological matrices of adult hares distributed by sex, and to highlight the need for monitoring this element in the natural environment. Determination of arsenic concentration was carried out on 11 biomarkers in 105 adult hares from variously loaded areas of the Czech Republic. Individual matrices include the liver, kidneys, brain, adipose tissue, reproductive organs, bone, fur, faeces, lungs, skeletal muscle and the heart. Inductively coupled plasma mass spectrometry was employed as a method to detect arsenic concentrations in the tissues. Arsenic deposition in the monitored biological matrices of adult animals showed no significant differences between sexes. The ratio of arsenic concentration in the skeletal muscle as compared with concentration in other tissues was 1:2.96 in the liver, followed by 1:4.35 in kidneys, 1:1.07 in the heart, 1:2.73 in lungs, 1:3.12 in ovaries, 1:3.30 in testicles, 1:5.90 in bones, 1:114.68 in fur, and 1:60.05 in faeces. Deposition of this element in matrices has a similar character and only differs in concentrations.
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[Rudolph Tegner: The blind from Marrakech (1949-1950)].
Norn, M; Permin, H
1999-01-01
The Danish sculptor and painter Rudolph Tegner (1873-1950) has built his own Museum in Dronningmolle, where his sculptures enrich the unique landscape. His last and incomplete plaster on a simple, raw wooden scaffold sculpture The Blind from Marrakech (Fig. 1) show five persons moan about, carrying a dead body. All persons are missing their arms. Tegner had a number of years earlier been in Marrakech and had watched a funeral procession, where blind beggars had carried a dead old woman raised high above the bearers on a kind of pall. In a small version of the statue cast, later in bronze from 1963, showed 15 bearers, on both sides of the bier (Fig. 2 & 3). Nine and 15 bearers are looking up, two right in front, and the rest are looking down. Totally blind people can not see the light but can see up to the divine Heaven. Some blind have kept the gleam. The confusion with the eye direction shows that they really are blind. However 10 of the 15 blind people had hollow in the eye (excenteratio orbitae) in contrast to the dead woman. The dead woman had been the blinds' mistress. The last work The Blind in Marrakech may also be the despair of the artist.
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Energy Technology Data Exchange (ETDEWEB)
NONE
1997-12-31
The overall aim of the project was to gain more knowledge about the kinetics of gas hydrate formation especially the early growth phase. Knowledge of kinetics of gas hydrate formation is important and measurements of gas hydrate particle size and concentration can contribute to improve this knowledge. An experimental setup for carrying out experimental studies of the nucleation and growth of gas hydrates has been constructed and tested. Multi wavelength extinction (MWE) was the experimental technique selected for obtaining particle diameter and concentration. The principle behind MWE is described as well as turbidity spectrum analysis that in an initial stage of the project was considered as an alternative experimental technique. Details of the experimental setup and its operation are outlined. The measuring cell consists of a 1 litre horizontal tube sustaining pressures up to 200 bar. Laser light for particle size determination can be applied through sapphire windows. A description of the various auxiliary equipment and of another gas hydrate cell used in the study are given. A computer program for simulation and analysis of gas hydrate experiments is based on the gas hydrate kinetics model proposed by Skovborg and Rasmussen (1993). Initial measurements showed that knowledge of the refractive index of gas hydrates was important in order to use MWE. An experimental determination of the refractive index of methane and natural gas hydrate is described. The test experiments performed with MWE on collectives of gas hydrate particles and experiments with ethane, methane and natural gas hydrate are discussed. Gas hydrate particles initially seem to grow mainly in size and at latter stages in number. (EG) EFP-94; 41 refs.
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Energy Technology Data Exchange (ETDEWEB)
NONE
1998-12-31
The overall aim of the project was to gain more knowledge about the kinetics of gas hydrate formation especially the early growth phase. Knowledge of kinetics of gas hydrate formation is important and measurements of gas hydrate particle size and concentration can contribute to improve this knowledge. An experimental setup for carrying out experimental studies of the nucleation and growth of gas hydrates has been constructed and tested. Multi wavelength extinction (MWE) was the experimental technique selected for obtaining particle diameter and concentration. The principle behind MWE is described as well as turbidity spectrum analysis that in an initial stage of the project was considered as an alternative experimental technique. Details of the experimental setup and its operation are outlined. The measuring cell consists of a 1 litre horizontal tube sustaining pressures up to 200 bar. Laser light for particle size determination can be applied through sapphire windows. A description of the various auxiliary equipment and of another gas hydrate cell used in the study are given. A computer program for simulation and analysis of gas hydrate experiments is based on the gas hydrate kinetics model proposed by Skovborg and Rasmussen (1993). Initial measurements showed that knowledge of the refractive index of gas hydrates was important in order to use MWE. An experimental determination of the refractive index of methane and natural gas hydrate is described. The test experiments performed with MWE on collectives of gas hydrate particles and experiments with ethane, methane and natural gas hydrate are discussed. Gas hydrate particles initially seem to grow mainly in size and at latter stages in number. (EG) EFP-94; 41 refs.
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Sliva, Amy L.; Gorman, Joe; Voshell, Martin; Tittle, James; Bowman, Christopher
2016-05-01
The Dual Node Decision Wheels (DNDW) architecture concept was previously described as a novel approach toward integrating analytic and decision-making processes in joint human/automation systems in highly complex sociotechnical settings. In this paper, we extend the DNDW construct with a description of components in this framework, combining structures of the Dual Node Network (DNN) for Information Fusion and Resource Management with extensions on Rasmussen's Decision Ladder (DL) to provide guidance on constructing information systems that better serve decision-making support requirements. The DNN takes a component-centered approach to system design, decomposing each asset in terms of data inputs and outputs according to their roles and interactions in a fusion network. However, to ensure relevancy to and organizational fitment within command and control (C2) processes, principles from cognitive systems engineering emphasize that system design must take a human-centered systems view, integrating information needs and decision making requirements to drive the architecture design and capabilities of network assets. In the current work, we present an approach for structuring and assessing DNDW systems that uses a unique hybrid DNN top-down system design with a human-centered process design, combining DNN node decomposition with artifacts from cognitive analysis (i.e., system abstraction decomposition models, decision ladders) to provide work domain and task-level insights at different levels in an example intelligence, surveillance, and reconnaissance (ISR) system setting. This DNDW structure will ensure not only that the information fusion technologies and processes are structured effectively, but that the resulting information products will align with the requirements of human decision makers and be adaptable to different work settings .
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Detection of Ichthyophonus by chromogenic in situ hybridization
Conway, Carla M.; Purcell, Maureen K.; Elliott, Diane G.; Hershberger, Paul K.
2015-01-01
Ichthyophonus hoferi (Plehn & Mulsow 1911) is a protistan parasite in the class Mesomycetozoea that infects a large range of marine and freshwater fish (Mendoza, Taylor & Ajello 2002; McVicar 2011). The broad host and geographic range, which includes both fresh and marine waters of the Northern and Southern Hemispheres, combined with a lack of distinguishing morphological characteristics, have prompted speculation that Ichthyophonus-like organisms in multiple species of fish, as well as reptiles, amphibians, birds and invertebrates, may have been incorrectly classified under a single type species I. hoferi (McVicar 2011). At present, only two species,I. hoferi and I. irregularis, are currently recognized within the genus (Rand et al. 2000; Mendoza et al. 2002). Investigations of ribosomal DNA sequence variation have begun to clarify relationships among Ichthyophonus types (Criscione et al. 2002; Rasmussen et al. 2010). Here, we will use the term Ichthyophonus to broadly represent all members of the genus regardless of species/subspecies.
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MR imaging in epilepsy that is refractory to medical therapy
International Nuclear Information System (INIS)
Cakirer, S.; Basak, M.; Mutlu, A.; Galip, G.M.
2002-01-01
The aim of this study was the assessment of detection rate on MRI and description of MRI findings in patients with medically intractable epilepsy. Seventy-three patients with medically intractable epilepsy between the ages of 0 and 68 years old were evaluated by MRI, on three planes with spin-echo T1, fast spin-echo T2, and fluid-attenuated inversion recovery sequences, and, if necessary, with contrast-enhanced SE T1 sequences. Cerebral infarct regions with atrophy and gliosis in 8 patients, cerebral tumors in 5 patients, hippocampal sclerosis in 16 patients, radial microbrain in 1 patient, cortical dysplasia in 3 patients, pachygyria in 2 patients, subcortical heterotopia in 2 patients, schizencephaly in 3 patients, cerebral hemiatrophy in 2 patients, tuberous sclerosis in 1 patient, herpes encephalitis in 2 patients, Rasmussen's encephalitis in 1 patient, vascular malformations in 5 patients, and no abnormality in 22 patients were detected. Magnetic resonance imaging has a high success rate in detecting structural brain abnormalities, of both temporal and extratemporal locations, associated with medically intractable epilepsy syndromes. So MRI plays a primary role in planning of the treatment, primarily surgical therapy, by detecting structural epileptogenic lesions. (orig.)
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Energy Technology Data Exchange (ETDEWEB)
Urbach, H. [University of Bonn Medical Center, Department of Radiology/Neuroradiology, Bonn (Germany)
2005-03-01
Imaging of epilepsy patients is challenging, since epileptogenic lesions (defined as structural lesions causally related to the epilepsy syndrome) may be small and often do not change during life. Prior clinical information about the epilepsy syndrome and the semiology of the seizures is needed in order to plan the examination properly. The effort to detect an epileptogenic lesion is directed to partial (focal) epilepsy syndromes whereas - by definition - no lesion is identified in idiopathic epilepsies. Most patients with partial epilepsies suffer from mesial temporal lobe epilepsies. In these patients, 2- to 3-mm-thick T2-weighted and fluid-attenuated inversion-recovery (FLAIR) fast spin echo slices along or perpendicular to the temporal lobe length axis have the highest diagnostic efficacy. In contrast, in patients with extratemporal lobe epilepsies perpendicular FLAIR slices through the anatomic region, from which, due to clinical and EEG criteria, the seizures are likely to originate, are preferred. The imaging features of common epileptogenic lesions (hippocampal sclerosis, long-term epilepsy-associated tumours, focal cortical dysplasias, vascular malformations, encephalitis including limbic and Rasmussen's encephalitis, gyral scarring including ulegyria) are detailed in the second section of this paper. (orig.)
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Peatland Ecosystem Processes in the Maritime Antarctic During Warm Climates.
Loisel, Julie; Yu, Zicheng; Beilman, David W; Kaiser, Karl; Parnikoza, Ivan
2017-09-27
We discovered a 50-cm-thick peat deposit near Cape Rasmussen (65.2°S), in the maritime Antarctic. To our knowledge, while aerobic 'moss banks' have often been examined, waterlogged 'peatlands' have never been described in this region before. The waterlogged system is approximately 100 m 2 , with a shallow water table. Surface vegetation is dominated by Warnstorfia fontinaliopsis, a wet-adapted moss commonly found in the Antarctic Peninsula. Peat inception was dated at 2750 cal. BP and was followed by relatively rapid peat accumulation (~0.1 cm/year) until 2150 cal. BP. Our multi-proxy analysis then shows a 2000-year-long stratigraphic hiatus as well as the recent resurgence of peat accumulation, sometime after 1950 AD. The existence of a thriving peatland at 2700-2150 cal. BP implies regionally warm summer conditions extending beyond the mid-Holocene; this finding is corroborated by many regional records showing moss bank initiation and decreased sea ice extent during this time period. Recent peatland recovery at the study site (maritime Antarctic region may promote a more peatland-rich landscape in the future.
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International Nuclear Information System (INIS)
Urbach, H.
2005-01-01
Imaging of epilepsy patients is challenging, since epileptogenic lesions (defined as structural lesions causally related to the epilepsy syndrome) may be small and often do not change during life. Prior clinical information about the epilepsy syndrome and the semiology of the seizures is needed in order to plan the examination properly. The effort to detect an epileptogenic lesion is directed to partial (focal) epilepsy syndromes whereas - by definition - no lesion is identified in idiopathic epilepsies. Most patients with partial epilepsies suffer from mesial temporal lobe epilepsies. In these patients, 2- to 3-mm-thick T2-weighted and fluid-attenuated inversion-recovery (FLAIR) fast spin echo slices along or perpendicular to the temporal lobe length axis have the highest diagnostic efficacy. In contrast, in patients with extratemporal lobe epilepsies perpendicular FLAIR slices through the anatomic region, from which, due to clinical and EEG criteria, the seizures are likely to originate, are preferred. The imaging features of common epileptogenic lesions (hippocampal sclerosis, long-term epilepsy-associated tumours, focal cortical dysplasias, vascular malformations, encephalitis including limbic and Rasmussen's encephalitis, gyral scarring including ulegyria) are detailed in the second section of this paper. (orig.)
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Skills, rules and knowledge in aircraft maintenance: errors in context
Hobbs, Alan; Williamson, Ann
2002-01-01
Automatic or skill-based behaviour is generally considered to be less prone to error than behaviour directed by conscious control. However, researchers who have applied Rasmussen's skill-rule-knowledge human error framework to accidents and incidents have sometimes found that skill-based errors appear in significant numbers. It is proposed that this is largely a reflection of the opportunities for error which workplaces present and does not indicate that skill-based behaviour is intrinsically unreliable. In the current study, 99 errors reported by 72 aircraft mechanics were examined in the light of a task analysis based on observations of the work of 25 aircraft mechanics. The task analysis identified the opportunities for error presented at various stages of maintenance work packages and by the job as a whole. Once the frequency of each error type was normalized in terms of the opportunities for error, it became apparent that skill-based performance is more reliable than rule-based performance, which is in turn more reliable than knowledge-based performance. The results reinforce the belief that industrial safety interventions designed to reduce errors would best be directed at those aspects of jobs that involve rule- and knowledge-based performance.
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International Nuclear Information System (INIS)
Meshkati, N.
2016-01-01
When complex technological systems, such as nuclear power plants, move from routine to non-routine (normal to emergency) operation, the control operators need to dynamically match the system’s new requirements. This mandates integrated and harmonious changes in information presentation, changes in performance requirements in part because of operators’ inevitable involuntary transition to different levels of cognitive control, and reconfigurations of the operators’ team (organizational) structure and communication. In order to survive, a technological system must have the ability to respond to operational anomalies before any undesirable consequences, which the system seeks to avoid, can occur. That is, the control structure must run at a faster rate than the environment it seeks to control; else-wise, the system will lose control. However, a hierarchically structured team has only a limited control model of the system, which oversees. For instance, in the case of a power plant particularly during an emergency, the operators not only comply with EOPs, they must also respond to the changing system environment. To the extent that every possible deviation in this environment has not been foreseen by the “hierarchy”, control is transferred to the work domain level—to operators—and due to their survival needs and instincts the system’s control team inevitably embraces structural forms that fit the situational demands, often the more naturalistic form such as “self-organizing”. Moreover, the hierarchical team structure becomes even more counter-productive when decisions need to be made by the whole team using the “team mind”. As task uncertainty increases in complex systems, (typical in “non-normal” or emergency situations), the number of exceptions to routine operations increases, overloading organizational hierarchy. In order to meet the new challenges, the organization must use another mechanism to sustain itself. Furthermore, the
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International Nuclear Information System (INIS)
Yoshino, Kenji; Hirotsu, Yuko; Fujimoto, Junzo; Gouda, Hidenori
2001-01-01
The purpose of this research is before hand prevention of the systematic error produced from the fault of command / command system on the different organization in a nuclear power plant, and the individual error of the demand level of maintenance work, and knowledge and experience level of a maintenance worker produced from it being incongruent (mismatch), and generating of the serious accident and a serious trouble. This research attains optimization with the difficulty of maintenance work, and work execution capability, such as the persons concerned (a supervision person, a construction person, work person), and proposes the new 'maintenance educational support technique' which is useful to the improvement in 'work reliability' and 'before hand prevention of a human error' in the maintenance work spot. The main results concerning this research are shown below. (1) In this research, concept design of RHR pump maintenance work educational support prototype system was performed on the basis of the examination result of a process analysis of RHR pump maintenance work, load mapping, a rule base/knowledge base and a data base/filing system. Consequently, when an educator-ed talked with a data base/filing system along with load mapping of maintenance work (Why, How, What), a possibility that it could reach exactly from work start to the sub goal or the last goal and timely was suggested. (2) As a result of classifying 'the difficulty of maintenance work', and man's work execution capability' and comparing the result using SRK (behavior of human) index which Rasmussen proposed, among both, it turns out that difference (inharmonious) arises. The exact presentation of the educational method or educational material which responded to knowledge and experience level of an educational achievement target or an educator-ed can be referred to as being connected with the improvement in work reliability, and before hand prevention of a human error as a result by then, incorporating
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Vasil'ev, A G; Bol'shakov, V N; Vasil'eva, I A; Evdokimov, N G; Sineva, N V
2018-01-01
Geometric morphometry has been used to reveal transformations of mandible morphogenesis in the offspring of mole voles resettled to the northern part of the species range from a southern population. The transformations were new compared to both the original (southern) and the aboriginal (northern) populations. A significant increase in the intragroup morphological disparity estimated by the mean nearest neighbor distance (MNND) in the resettled animals compared to both aboriginal populations is an indirect indication of an increased developmental instability in the resettled animals exposed to new climatic conditions.
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Kuusk, Priit, 1938-
2001-01-01
Ukraina nõustus tagastama Saksamaale C.P.E. Bachi muusikakäsikirjad, mis Nõukogude Liidu armee sealt II Maailmasõja ajal ära viis. Inglise Rahvusooperis lavastuvast D.Saweri ooperist "From Morning to Midnight". M.Theodorakise kolm ooperit (antiiktriloogia "Elektra", "Antigone" ja "Medeia") ilmusid seoses maestro 75. juubeliga kaheksal CD-plaadil. Lühidalt D.Golubist. Põhjamaade Nõukogu tänavuse muusikapreemia võitis P.Mikkelborg
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DEFF Research Database (Denmark)
Mameniskiene, Ruta; Bast, Thomas; Bentes, Carla
2011-01-01
To gain new insights into the clinical presentation, causes, treatment and prognosis of epilepsia partialis continua (EPC), and to develop hypotheses to be tested in a prospective investigation.......To gain new insights into the clinical presentation, causes, treatment and prognosis of epilepsia partialis continua (EPC), and to develop hypotheses to be tested in a prospective investigation....
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Análise locacional e impactos econômicos do segmento sucroalcooleiro em Mato Grosso
Directory of Open Access Journals (Sweden)
Wladimir Colman de Azevedo Junior
2012-01-01
Full Text Available O cultivo da cana-de-açúcar tem se intensificado na região central do Brasil e oestado de Mato Grosso tornou-se um dos principais produtores de etanol e açúcardo país. Entender o comportamento desta cadeia, considerando a caracterizaçãoeconômica espacial do cultivo e os efeitos multiplicadores sobre a economia éimportante para sabermos a magnitude de cada atividade e sua importância para odesenvolvimento local. Para mensurar os efeitos multiplicadores foi utilizada a MatrizInsumo-Produto (MIP de Mato Grosso, atualizada para o ano de 2007, que permitiua construção dos índices de ligações Rasmussen-Hirschman e dos efeitosmultiplicadores. A identificação da concentração territorial do cultivo da cana-deaçúcarfoi possível por meio do Índice de Concentração Normalizado (ICN, queutiliza dados do PIB e do valor da produção para mapear os espaços cuja referidaatividade é tida como economicamente diferenciada. O resultado auferido reflete queo elo industrial da cadeia possui forte poder de dispersão de investimento e que em2007 se localizava em apenas 11 municípios no estado. O elo agrícola da cadeiaapresentou forte sensibilidade de dispersão e também se localiza em 11 municípiostidos como diferenciados e que por isto concentram a produção da cana em seusterritórios.Abstract The cultivation of sugar cane has intensified in the central region of Brazil andthe state of Mato Grosso has become a leading producer of ethanol and sugar in thecountry. Understanding the behavior of this chain, considering the characterization ofgrowing economic space and the multiplier effects on the economy is important toknow the magnitude of each activity and its importance for local development. Tomeasure the multiplier effects we used the input-output matrix (IPM of Mato Grosso,updated to the year 2007, which allowed the construction of indexes linksRasmussen-Hirschman and multiplier effects. The identification of
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Gorman, J.; Voshell, M.; Sliva, A.
2016-09-01
The United States is highly dependent on space resources to support military, government, commercial, and research activities. Satellites operate at great distances, observation capacity is limited, and operator actions and observations can be significantly delayed. Safe operations require support systems that provide situational understanding, enhance decision making, and facilitate collaboration between human operators and system automation both in-the-loop, and on-the-loop. Joint cognitive systems engineering (JCSE) provides a rich set of methods for analyzing and informing the design of complex systems that include both human decision-makers and autonomous elements as coordinating teammates. While, JCSE-based systems can enhance a system analysts' understanding of both existing and new system processes, JCSE activities typically occur outside of traditional systems engineering (SE) methods, providing sparse guidance about how systems should be implemented. In contrast, the Joint Director's Laboratory (JDL) information fusion model and extensions, such as the Dual Node Network (DNN) technical architecture, provide the means to divide and conquer such engineering and implementation complexity, but are loosely coupled to specialized organizational contexts and needs. We previously describe how Dual Node Decision Wheels (DNDW) extend the DNN to integrate JCSE analysis and design with the practicalities of system engineering and implementation using the DNN. Insights from Rasmussen's JCSE Decision Ladders align system implementation with organizational structures and processes. In the current work, we present a novel approach to assessing system performance based on patterns occurring in operational decisions that are documented by JCSE processes as traces in a decision ladder. In this way, system assessment is closely tied not just to system design, but the design of the joint cognitive system that includes human operators, decision-makers, information systems, and
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Applying systems ergonomics methods in sport: A systematic review.
Hulme, Adam; Thompson, Jason; Plant, Katherine L; Read, Gemma J M; Mclean, Scott; Clacy, Amanda; Salmon, Paul M
2018-04-16
As sports systems become increasingly more complex, competitive, and technology-centric, there is a greater need for systems ergonomics methods to consider the performance, health, and safety of athletes in context with the wider settings in which they operate. Therefore, the purpose of this systematic review was to identify and critically evaluate studies which have applied a systems ergonomics research approach in the context of sports performance and injury management. Five databases (PubMed, Scopus, ScienceDirect, Web of Science, and SPORTDiscus) were searched for the dates 01 January 1990 to 01 August 2017, inclusive, for original peer-reviewed journal articles and conference papers. Reported analyses were underpinned by a recognised systems ergonomics method, and study aims were related to the optimisation of sports performance (e.g. communication, playing style, technique, tactics, or equipment), and/or the management of sports injury (i.e. identification, prevention, or treatment). A total of seven articles were identified. Two articles were focussed on understanding and optimising sports performance, whereas five examined sports injury management. The methods used were the Event Analysis of Systemic Teamwork, Cognitive Work Analysis (the Work Domain Analysis Abstraction Hierarchy), Rasmussen's Risk Management Framework, and the Systems Theoretic Accident Model and Processes method. The individual sport application was distance running, whereas the team sports contexts examined were cycling, football, Australian Football League, and rugby union. The included systems ergonomics applications were highly flexible, covering both amateur and elite sports contexts. The studies were rated as valuable, providing descriptions of injury controls and causation, the factors influencing injury management, the allocation of responsibilities for injury prevention, as well as the factors and their interactions underpinning sports performance. Implications and future
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Taking stock of Saddam's fiery legacy in Kuwait
Energy Technology Data Exchange (ETDEWEB)
Hoffman, M.
1991-08-30
Six months after Saddam Hussein's torching of more than 700 Kuwaiti oil wells, health officials, meteorologists, and environmental experts convened during mid-August in Cambridge, Massachusetts, to assess the impact of the fires. The soot cloud produced by the fires hasn't produced a nuclear winter, nor are the carbon dioxide and other gases released going to have an appreciable effect on global warming, although regional weather changes are possible. So far adverse health effects from the heavy pall of pollution caused by the fires have been surprisingly mild. This isn't to say that premature deaths will not occur, but many scientists had feared much worse. Nevertheless, all researchers concede that the data for this particular conclusion are still preliminary, and they expressed concerns that health problems may worsen in the coming months. Most of the health effects are expected in a region blanketed by a plume of smoke 800 to 1,000 kilometers long. The average concentrations of the primary pollutants it contains, carbon-based particles and sulfur dioxide, are similar to those in any large urban center. Still, the oil fires increase the pollution burden on Kuwait, which already had a problem with particulates in the air, and some epidemiologists expect that the extra pollutants will take their toll.
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International Nuclear Information System (INIS)
Yan, Shuiping; Fang, Mengxiang; Zhang, Weifeng; Zhong, Weilong; Luo, Zhongyang; Cen, Kefa
2008-01-01
This paper firstly evaluated the CO 2 absorption performance of a membrane gas absorption system (MAS) and chemical absorption system (CAS) using the overall mass transfer coefficient (K G a V ) as a basis for comparison. MAS selected microporous polypropylene (PP) hollow fiber membrane contactors to capture CO 2 from the simulated flue gas while CAS used a randomly packed column containing stainless Pall packing. Aqueous monoethanolamine (MEA) solution was adopted in both absorbers. Experimental results show that if the fresh membranes were tested, MAS has the higher K G a V values than that of CAS. However, when all the membrane pores were completely wetted or 50% pores were plugged, CAS inversely performs better than MAS in terms of K G a V values. In addition, the economic performance of MAS and CAS was also estimated. Results indicate that if the real operational time of membrane module is reduced to less than the critical value affected by the membrane price, the CO 2 captured cost of MAS is inversely higher than that of CAS. Therefore, the current well-accepted statement that MAS is superior to CAS in any case may be somewhat arbitrary unless membrane pore-wetting and pore-plugging problems, how to reduce the membrane price and how to prolong the membrane lifetime can be solved perfectly in the future. (author)
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Characterization of the Anti-Influenza Activity of the Chinese Herbal Plant Paeonia lactiflora
Directory of Open Access Journals (Sweden)
Jin-Yuan Ho
2014-04-01
Full Text Available Bai Shao (BS, the root of Paeonia lactiflora Pall., a common Chinese herb in many recipes used to treat viral infection and liver diseases, is recognized for its ability to nourish menstruation, its Yin convergence, and as an antiperspirant. However, the mechanism and components for its antiviral function remain to be elucidated. In this study, an ethanolic extract of BS was further partitioned into aqueous and organic parts (EAex for in vitro functional study and in vivo efficacy testing. EAex exhibited an IC50 of 0.016 ± 0.005 mg/mL against influenza virus A/WSN/33 (H1N1, with broad-spectrum inhibitory activity against different strains of human influenza A viruses, including clinical oseltamivir-resistant isolates and an H1N1pdm strain. The synthesis of both viral RNA and protein was profoundly inhibited when the cells were treated with EAex. A time-of-addition assay demonstrated that EAex exerted its antiviral activity at various stages of the virus replication cycle. We addressed its antiviral activity at virus entry and demonstrated that EAex inhibits viral hemagglutination and viral binding to and penetration into host cells. In vivo animal testing showed that 200 mg/kg/d of EAex offered significant protection against viral infection. We conclude that BS possesses antiviral activity and has the potential for development as an anti-influenza agent.
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Zhang, Xiao-Jun; Chen, Hong-Li; Li, Zhi; Zhang, Hong-Qi; Xu, Hong-Xi; Sung, Joseph J Y; Bian, Zhao-Xiang
2009-11-01
Paeoniflorin (PF), a chief active ingredient in the root of Paeonia lactiflora Pall (family Ranunculaceae), is effective in relieving colorectal distention (CRD)-induced visceral pain in rats with visceral hyperalgesia induced by neonatal maternal separation (NMS). This study aimed at exploring the underlying mechanisms of PF's analgesic effect on CRD-evoked nociceptive signaling in the central nervous system (CNS) and investigating whether the adenosine A(1) receptor is involved in PF's anti-nociception. CRD-induced visceral pain as well as phosphorylated-extracellular signal-regulated protein kinase (p-ERK) and phospho-cAMP response element-binding protein (p-CREB) expression in the CNS structures of NMS rats were suppressed by NMDA receptor antagonist dizocilpine (MK-801) and ERK phosphorylation inhibitor U0126. PF could similarly inhibit CRD-evoked p-ERK and c-Fos expression in laminae I-II of the lumbosacral dorsal horn and anterior cingulate cortex (ACC). PF could also reverse the CRD-evoked increased glutamate concentration by CRD as shown by dynamic microdialysis monitoring in ACC, whereas, DPCPX, an antagonist of adenosine A(1) receptor, significantly blocked the analgesic effect of PF and PF's inhibition on CRD-induced p-ERK and p-CREB expression. These results suggest that PF's analgesic effect is possibly mediated by adenosine A(1) receptor by inhibiting CRD-evoked glutamate release and the NMDA receptor dependent ERK signaling.
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Validation testing of radioactive waste drum filter vents
Energy Technology Data Exchange (ETDEWEB)
Weber, L.D. [Pall Corp., Port Washington, NY (United States); Rahimi, R.S. [Pall Corp., Cortland, NY (United States); Edling, D. [Edling & Associates, Inc., Russel Springs, KY (United States)
1997-08-01
The minimum requirements for Drum Filter Vents (DFVs) can be met by demonstrating conformance with the Waste Isolation Pilot Plant (WIPP) Trupact II Safety Assessment Report (SAR), and conformance with U.S. Federal shipping regulations 49 CFR 178.350, DOT Spec 7A, for Type A packages. These together address a number of safety related performance parameters such as hydrogen diffusivity, flow related pressure drop, filtration efficiency and, separately, mechanical stability and the ability to prevent liquid water in-leakage. In order to make all metal DFV technology (including metallic filter medium) available to DOE sites, Pall launched a product development program to validate an all metal design to meet these requirements. Numerous problems experienced by DOE sites in the past came to light during this development program. They led us to explore enhancements to DFV design and performance testing addressing these difficulties and concerns. The result is a patented all metal DFV certified to all applicable regulatory requirements, which for the first time solves operational and health safety problems reported by DOE site personnel but not addressed by previous DFV`s. The new technology facilitates operations (such as manual, automated and semi-automated drum handling/redrumming), sampling, on-site storage, and shipping. At the same time, it upgrades filtration efficiency in configurations documented to maintain filter efficiency following mechanical stress. 2 refs., 2 figs., 10 tabs.
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Model-model Perencanaan Strategik
Amirin, Tatang M
2005-01-01
The process of strategic planning, used to be called as long-term planning, consists of several components, including strategic analysis, setting strategic direction (covering of mission, vision, and values), and action planning. Many writers develop models representing the steps of the strategic planning process, i.e. basic planning model, problem-based planning model, scenario model, and organic or self-organizing model.
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Model-to-model interface for multiscale materials modeling
Energy Technology Data Exchange (ETDEWEB)
Antonelli, Perry Edward [Iowa State Univ., Ames, IA (United States)
2017-12-17
A low-level model-to-model interface is presented that will enable independent models to be linked into an integrated system of models. The interface is based on a standard set of functions that contain appropriate export and import schemas that enable models to be linked with no changes to the models themselves. These ideas are presented in the context of a specific multiscale material problem that couples atomistic-based molecular dynamics calculations to continuum calculations of fluid ow. These simulations will be used to examine the influence of interactions of the fluid with an adjacent solid on the fluid ow. The interface will also be examined by adding it to an already existing modeling code, Large-scale Atomic/Molecular Massively Parallel Simulator (LAMMPS) and comparing it with our own molecular dynamics code.
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ten Cate, Jacob M
2015-01-01
Developing experimental models to understand dental caries has been the theme in our research group. Our first, the pH-cycling model, was developed to investigate the chemical reactions in enamel or dentine, which lead to dental caries. It aimed to leverage our understanding of the fluoride mode of action and was also utilized for the formulation of oral care products. In addition, we made use of intra-oral (in situ) models to study other features of the oral environment that drive the de/remineralization balance in individual patients. This model addressed basic questions, such as how enamel and dentine are affected by challenges in the oral cavity, as well as practical issues related to fluoride toothpaste efficacy. The observation that perhaps fluoride is not sufficiently potent to reduce dental caries in the present-day society triggered us to expand our knowledge in the bacterial aetiology of dental caries. For this we developed the Amsterdam Active Attachment biofilm model. Different from studies on planktonic ('single') bacteria, this biofilm model captures bacteria in a habitat similar to dental plaque. With data from the combination of these models, it should be possible to study separate processes which together may lead to dental caries. Also products and novel agents could be evaluated that interfere with either of the processes. Having these separate models in place, a suggestion is made to design computer models to encompass the available information. Models but also role models are of the utmost importance in bringing and guiding research and researchers. 2015 S. Karger AG, Basel
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Hydrological models are mediating models
Babel, L. V.; Karssenberg, D.
2013-08-01
Despite the increasing role of models in hydrological research and decision-making processes, only few accounts of the nature and function of models exist in hydrology. Earlier considerations have traditionally been conducted while making a clear distinction between physically-based and conceptual models. A new philosophical account, primarily based on the fields of physics and economics, transcends classes of models and scientific disciplines by considering models as "mediators" between theory and observations. The core of this approach lies in identifying models as (1) being only partially dependent on theory and observations, (2) integrating non-deductive elements in their construction, and (3) carrying the role of instruments of scientific enquiry about both theory and the world. The applicability of this approach to hydrology is evaluated in the present article. Three widely used hydrological models, each showing a different degree of apparent physicality, are confronted to the main characteristics of the "mediating models" concept. We argue that irrespective of their kind, hydrological models depend on both theory and observations, rather than merely on one of these two domains. Their construction is additionally involving a large number of miscellaneous, external ingredients, such as past experiences, model objectives, knowledge and preferences of the modeller, as well as hardware and software resources. We show that hydrological models convey the role of instruments in scientific practice by mediating between theory and the world. It results from these considerations that the traditional distinction between physically-based and conceptual models is necessarily too simplistic and refers at best to the stage at which theory and observations are steering model construction. The large variety of ingredients involved in model construction would deserve closer attention, for being rarely explicitly presented in peer-reviewed literature. We believe that devoting
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Bošnjak, Marija; Sremac, Jasenka; Vrsaljko, Davor; Aščić, Šimun; Bosak, Luka
2017-08-01
Deep marine Miocene deposits exposed sporadically in the Medvednica Mt. (northern Croatia) comprise pelagic organisms such as coccolithophores, planktic foraminifera and pteropods. The pteropod fauna from yellow marls at the Vejalnica locality (central part of Medvednica Mt.) encompasses abundant specimens of Vaginella austriaca Kittl, 1886, accompanied with scarce Clio fallauxi (Kittl, 1886). Calcareous nannoplankton points to the presence of NN5 nannozone at this locality. Highly fossiliferous grey marls at the Marija Bistrica locality (north-eastern area of Medvednica Mt.) comprise limacinid pteropods: Limacina valvatina (Reuss, 1867), L. gramensis (Rasmussen, 1968) and Limacina sp. Late Badenian (NN5 to NN6 nannozone) age of these marls is presumed on the basis of coccolithophores. Most of the determined pteropods on species level, except V. austriaca have been found and described from this region for the first time. New pteropod records from Croatia point to two pteropod horizons coinciding with the Badenian marine transgressions in Central Paratethys. These pteropod assemblages confirm the existence of W-E marine connection ("Transtethyan Trench Corridor") during the Badenian NN5 nannozone. Limacinids point to the possible immigration of the "North Sea fauna" through a northern European marine passage during the Late Badenian (end of NN5-beginning of NN6 zone), as previously presumed by some other authors.
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Basic principles and results of the German risk study
International Nuclear Information System (INIS)
Heuser, F.W.; Bayer, A.
1980-01-01
In June 1976 the Federal Ministry for Research and Technology had commissioned the Gesellschaft fuer Reaktorsicherheit to write the German Risk Study, the first part of which has now been completed after three years of work and has been publicized recently. The German Risk Study is an attempt to define the societal risk posed by accidents in nuclear power plants under conditions in Germany. For this purpose, the accident rates and the resultant health hazards were determined. By adopting most of the basic premises and methods of the American Rasmussen Study, the German study is to allow a comparison to be made with the results of that study. The calculations were based on 19 sites with a total of 25 nuclear generating units presently in operation, under construction or in the licensing procedure in the Federal Republic of Germany. The technical studies were conducted on a 1300 MW PWR as the representative example. The results show that the decisive contributions are made by uncontrolled minor loss-of-coolant accidents and by failures of power supply (emergency power case). Large loss-of-coolant accidents do not play a role. The study also shows the decisive safety function of the containment. (orig.) [de
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Modeling Documents with Event Model
Directory of Open Access Journals (Sweden)
Longhui Wang
2015-08-01
Full Text Available Currently deep learning has made great breakthroughs in visual and speech processing, mainly because it draws lessons from the hierarchical mode that brain deals with images and speech. In the field of NLP, a topic model is one of the important ways for modeling documents. Topic models are built on a generative model that clearly does not match the way humans write. In this paper, we propose Event Model, which is unsupervised and based on the language processing mechanism of neurolinguistics, to model documents. In Event Model, documents are descriptions of concrete or abstract events seen, heard, or sensed by people and words are objects in the events. Event Model has two stages: word learning and dimensionality reduction. Word learning is to learn semantics of words based on deep learning. Dimensionality reduction is the process that representing a document as a low dimensional vector by a linear mode that is completely different from topic models. Event Model achieves state-of-the-art results on document retrieval tasks.
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Semiparametric modeling: Correcting low-dimensional model error in parametric models
International Nuclear Information System (INIS)
Berry, Tyrus; Harlim, John
2016-01-01
In this paper, a semiparametric modeling approach is introduced as a paradigm for addressing model error arising from unresolved physical phenomena. Our approach compensates for model error by learning an auxiliary dynamical model for the unknown parameters. Practically, the proposed approach consists of the following steps. Given a physics-based model and a noisy data set of historical observations, a Bayesian filtering algorithm is used to extract a time-series of the parameter values. Subsequently, the diffusion forecast algorithm is applied to the retrieved time-series in order to construct the auxiliary model for the time evolving parameters. The semiparametric forecasting algorithm consists of integrating the existing physics-based model with an ensemble of parameters sampled from the probability density function of the diffusion forecast. To specify initial conditions for the diffusion forecast, a Bayesian semiparametric filtering method that extends the Kalman-based filtering framework is introduced. In difficult test examples, which introduce chaotically and stochastically evolving hidden parameters into the Lorenz-96 model, we show that our approach can effectively compensate for model error, with forecasting skill comparable to that of the perfect model.
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Vector models and generalized SYK models
Energy Technology Data Exchange (ETDEWEB)
Peng, Cheng [Department of Physics, Brown University,Providence RI 02912 (United States)
2017-05-23
We consider the relation between SYK-like models and vector models by studying a toy model where a tensor field is coupled with a vector field. By integrating out the tensor field, the toy model reduces to the Gross-Neveu model in 1 dimension. On the other hand, a certain perturbation can be turned on and the toy model flows to an SYK-like model at low energy. A chaotic-nonchaotic phase transition occurs as the sign of the perturbation is altered. We further study similar models that possess chaos and enhanced reparameterization symmetries.
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[Bone remodeling and modeling/mini-modeling.
Hasegawa, Tomoka; Amizuka, Norio
Modeling, adapting structures to loading by changing bone size and shapes, often takes place in bone of the fetal and developmental stages, while bone remodeling-replacement of old bone into new bone-is predominant in the adult stage. Modeling can be divided into macro-modeling(macroscopic modeling)and mini-modeling(microscopic modeling). In the cellular process of mini-modeling, unlike bone remodeling, bone lining cells, i.e., resting flattened osteoblasts covering bone surfaces will become active form of osteoblasts, and then, deposit new bone onto the old bone without mediating osteoclastic bone resorption. Among the drugs for osteoporotic treatment, eldecalcitol(a vitamin D3 analog)and teriparatide(human PTH[1-34])could show mini-modeling based bone formation. Histologically, mature, active form of osteoblasts are localized on the new bone induced by mini-modeling, however, only a few cell layer of preosteoblasts are formed over the newly-formed bone, and accordingly, few osteoclasts are present in the region of mini-modeling. In this review, histological characteristics of bone remodeling and modeling including mini-modeling will be introduced.
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ROCK PROPERTIES MODEL ANALYSIS MODEL REPORT
International Nuclear Information System (INIS)
Clinton Lum
2002-01-01
The purpose of this Analysis and Model Report (AMR) is to document Rock Properties Model (RPM) 3.1 with regard to input data, model methods, assumptions, uncertainties and limitations of model results, and qualification status of the model. The report also documents the differences between the current and previous versions and validation of the model. The rock properties models are intended principally for use as input to numerical physical-process modeling, such as of ground-water flow and/or radionuclide transport. The constraints, caveats, and limitations associated with this model are discussed in the appropriate text sections that follow. This work was conducted in accordance with the following planning documents: WA-0344, ''3-D Rock Properties Modeling for FY 1998'' (SNL 1997, WA-0358), ''3-D Rock Properties Modeling for FY 1999'' (SNL 1999), and the technical development plan, Rock Properties Model Version 3.1, (CRWMS MandO 1999c). The Interim Change Notice (ICNs), ICN 02 and ICN 03, of this AMR were prepared as part of activities being conducted under the Technical Work Plan, TWP-NBS-GS-000003, ''Technical Work Plan for the Integrated Site Model, Process Model Report, Revision 01'' (CRWMS MandO 2000b). The purpose of ICN 03 is to record changes in data input status due to data qualification and verification activities. These work plans describe the scope, objectives, tasks, methodology, and implementing procedures for model construction. The constraints, caveats, and limitations associated with this model are discussed in the appropriate text sections that follow. The work scope for this activity consists of the following: (1) Conversion of the input data (laboratory measured porosity data, x-ray diffraction mineralogy, petrophysical calculations of bound water, and petrophysical calculations of porosity) for each borehole into stratigraphic coordinates; (2) Re-sampling and merging of data sets; (3) Development of geostatistical simulations of porosity; (4
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Automated protein structure modeling with SWISS-MODEL Workspace and the Protein Model Portal.
Bordoli, Lorenza; Schwede, Torsten
2012-01-01
Comparative protein structure modeling is a computational approach to build three-dimensional structural models for proteins using experimental structures of related protein family members as templates. Regular blind assessments of modeling accuracy have demonstrated that comparative protein structure modeling is currently the most reliable technique to model protein structures. Homology models are often sufficiently accurate to substitute for experimental structures in a wide variety of applications. Since the usefulness of a model for specific application is determined by its accuracy, model quality estimation is an essential component of protein structure prediction. Comparative protein modeling has become a routine approach in many areas of life science research since fully automated modeling systems allow also nonexperts to build reliable models. In this chapter, we describe practical approaches for automated protein structure modeling with SWISS-MODEL Workspace and the Protein Model Portal.
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A multi-archive coherent chronology: from Greenland to the Mediterranean sea
Bazin, Lucie; Landais, Amaelle; Lemieux-Dudon, Bénédicte; Siani, Giuseppe; Michel, Elisabeth; Combourieu-Nebout, Nathalie; Blamart, Dominique; Genty, Dominique
2015-04-01
Understanding the climate mechanisms requires a precise knowledge of the sequence of events during major climate changes. In order to provide precise relationships between changes in orbital and/or greenhouse gases concentration forcing, sea level changes and high vs low latitudes temperatures, a common chronological framework for different paleoclimatic archives is required. Coherent chronologies for ice cores have been recently produced using a bayesian dating tool, DATICE (Lemieux-Dudon et al., 2010, Bazin et al., 2013, Veres et al., 2013). Such tool has been recently developed to include marine cores and speleothems in addition to ice cores. This new development should enable one to test the coherency of different chronologies using absolute and stratigraphic links as well as to provide relationship between climatic changes recorded in different archives. We present here a first application of multi-archive coherent dating including paleoclimatic archives from (1) Greenland (NGRIP ice core), (2) Mediterranean sea (marine core MD90-917, 41° N17° E, 1010 m) and (3) speleothems from the South of France and North Tunisia (Chauvet, Villars and La Mine speleothems, Genty et al., 2006). Thanks to the good absolute chronological constraints from annual layer counting in NGRIP, 14C and tephra layers in MD90-917 and U-Th dating in speleothems, we can provide a precise chronological framework for the last 50 ka (ie. thousand years before present). Then, we present different tests on how to combine the records from the different archives and give the most plausible scenario for the sequence of events at different latitudes over the last deglaciation. Bazin, L., Landais, A. ; Lemieu¬-Dudon, B. ; Kele, H. T. M. ; Veres, D. ; Parrenin, F. ; Martinerie, P. ; Ritz, C. ; Capron, E. ; Lipenkov, V. ; Loutre, M.-F. ; Raynaud, D. ; Vinther, B. ; Svensson, A. ; Rasmussen, S. ; Severi, M. ; Blunier, T. ; Leuenberger, M. ; Fischer, H. ; Masson-¬-Delmotte, V. ; Chappellaz, J
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Indicaciones quirúrgicas de la epilepsia en la niñez Surgical indications in pediatric epilepsy
Directory of Open Access Journals (Sweden)
María Isabel Bragatti Winckler
2007-01-01
Full Text Available Con el objetivo de presentar el seguimiento de los pacientes ambulatorios de la clínica de epilepsia refractaria del Hospital de Clínicas de Porto Alegre (HCPA, Brasil, se hizo una revisión de la literatura de las epilepsias y síndromes epilépticos del niño y del adolescente, las indicaciones quirúrgicas y los métodos de evaluación. Los casos de epilepsia recomendados por la Subcomisión de Cirugía de la Epilepsia Pediátrica de la Liga Internacional Contra las Epilepsias para evaluación quirúrgica son: displasia cortical, esclerosis tuberosa, polimicrogiria, hamartoma hipotalámico, síndromes hemisféricos, síndromes de Sturge-Weber, Síndrome de Rasmussen, Síndrome de Landau-Kleffner y otras situaciones como tumores o alteraciones vasculares. Se recomienda la formación de centros de referencia que cuenten con métodos de evaluación funcional y de neuroimagen, así como equipo multidisciplinario formado por neurólogos, neurocirujanos, neurofisiólogos, neuropediatras, neuropsicólogos, patólogos, neurorradiólogos y técnicos en electroneurofisiología que mantengan los estándares impuestos de forma estricta. La formación de estos centros en países en desarrollo parece viable, con la cooperación de las regiones con mayores recursos. Numerosos estudios han demostrado una mejoría de la calidad de vida con reducción en la frecuencia de crisis diarias. En el HCPA se desarrolla un estudio de seguimiento ambulatorio de casos de epilepsias refractarias todavía en investigación y tratamiento clínico. La cirugía de la epilepsia es potencialmente curativa y es posible utilizarla en la población infantil.With the goal of presenting follow-up data from patients seen at the Refractory Epilepsy out-patient clinic of the Hospital de Clínicas de Porto Alegre (HCPA, Brazil, we reviewed the literature on childhood and adolescent epilepsy and epileptic syndromes with indication for surgical treatment. The International League
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Geologic Framework Model Analysis Model Report
Energy Technology Data Exchange (ETDEWEB)
R. Clayton
2000-12-19
The purpose of this report is to document the Geologic Framework Model (GFM), Version 3.1 (GFM3.1) with regard to data input, modeling methods, assumptions, uncertainties, limitations, and validation of the model results, qualification status of the model, and the differences between Version 3.1 and previous versions. The GFM represents a three-dimensional interpretation of the stratigraphy and structural features of the location of the potential Yucca Mountain radioactive waste repository. The GFM encompasses an area of 65 square miles (170 square kilometers) and a volume of 185 cubic miles (771 cubic kilometers). The boundaries of the GFM were chosen to encompass the most widely distributed set of exploratory boreholes (the Water Table or WT series) and to provide a geologic framework over the area of interest for hydrologic flow and radionuclide transport modeling through the unsaturated zone (UZ). The depth of the model is constrained by the inferred depth of the Tertiary-Paleozoic unconformity. The GFM was constructed from geologic map and borehole data. Additional information from measured stratigraphy sections, gravity profiles, and seismic profiles was also considered. This interim change notice (ICN) was prepared in accordance with the Technical Work Plan for the Integrated Site Model Process Model Report Revision 01 (CRWMS M&O 2000). The constraints, caveats, and limitations associated with this model are discussed in the appropriate text sections that follow. The GFM is one component of the Integrated Site Model (ISM) (Figure l), which has been developed to provide a consistent volumetric portrayal of the rock layers, rock properties, and mineralogy of the Yucca Mountain site. The ISM consists of three components: (1) Geologic Framework Model (GFM); (2) Rock Properties Model (RPM); and (3) Mineralogic Model (MM). The ISM merges the detailed project stratigraphy into model stratigraphic units that are most useful for the primary downstream models and the
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Geologic Framework Model Analysis Model Report
International Nuclear Information System (INIS)
Clayton, R.
2000-01-01
The purpose of this report is to document the Geologic Framework Model (GFM), Version 3.1 (GFM3.1) with regard to data input, modeling methods, assumptions, uncertainties, limitations, and validation of the model results, qualification status of the model, and the differences between Version 3.1 and previous versions. The GFM represents a three-dimensional interpretation of the stratigraphy and structural features of the location of the potential Yucca Mountain radioactive waste repository. The GFM encompasses an area of 65 square miles (170 square kilometers) and a volume of 185 cubic miles (771 cubic kilometers). The boundaries of the GFM were chosen to encompass the most widely distributed set of exploratory boreholes (the Water Table or WT series) and to provide a geologic framework over the area of interest for hydrologic flow and radionuclide transport modeling through the unsaturated zone (UZ). The depth of the model is constrained by the inferred depth of the Tertiary-Paleozoic unconformity. The GFM was constructed from geologic map and borehole data. Additional information from measured stratigraphy sections, gravity profiles, and seismic profiles was also considered. This interim change notice (ICN) was prepared in accordance with the Technical Work Plan for the Integrated Site Model Process Model Report Revision 01 (CRWMS M and O 2000). The constraints, caveats, and limitations associated with this model are discussed in the appropriate text sections that follow. The GFM is one component of the Integrated Site Model (ISM) (Figure l), which has been developed to provide a consistent volumetric portrayal of the rock layers, rock properties, and mineralogy of the Yucca Mountain site. The ISM consists of three components: (1) Geologic Framework Model (GFM); (2) Rock Properties Model (RPM); and (3) Mineralogic Model (MM). The ISM merges the detailed project stratigraphy into model stratigraphic units that are most useful for the primary downstream models and
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DEFF Research Database (Denmark)
Carlson, Kerstin
The International Criminal Tribunal for the former Yugoslavia (ICTY) was the first and most celebrated of a wave of international criminal tribunals (ICTs) built in the 1990s designed to advance liberalism through international criminal law. Model(ing) Justice examines the case law of the ICTY...
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Hong, Sehee; Kim, Soyoung
2018-01-01
There are basically two modeling approaches applicable to analyzing an actor-partner interdependence model: the multilevel modeling (hierarchical linear model) and the structural equation modeling. This article explains how to use these two models in analyzing an actor-partner interdependence model and how these two approaches work differently. As an empirical example, marital conflict data were used to analyze an actor-partner interdependence model. The multilevel modeling and the structural equation modeling produced virtually identical estimates for a basic model. However, the structural equation modeling approach allowed more realistic assumptions on measurement errors and factor loadings, rendering better model fit indices.
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Translating building information modeling to building energy modeling using model view definition.
Jeong, WoonSeong; Kim, Jong Bum; Clayton, Mark J; Haberl, Jeff S; Yan, Wei
2014-01-01
This paper presents a new approach to translate between Building Information Modeling (BIM) and Building Energy Modeling (BEM) that uses Modelica, an object-oriented declarative, equation-based simulation environment. The approach (BIM2BEM) has been developed using a data modeling method to enable seamless model translations of building geometry, materials, and topology. Using data modeling, we created a Model View Definition (MVD) consisting of a process model and a class diagram. The process model demonstrates object-mapping between BIM and Modelica-based BEM (ModelicaBEM) and facilitates the definition of required information during model translations. The class diagram represents the information and object relationships to produce a class package intermediate between the BIM and BEM. The implementation of the intermediate class package enables system interface (Revit2Modelica) development for automatic BIM data translation into ModelicaBEM. In order to demonstrate and validate our approach, simulation result comparisons have been conducted via three test cases using (1) the BIM-based Modelica models generated from Revit2Modelica and (2) BEM models manually created using LBNL Modelica Buildings library. Our implementation shows that BIM2BEM (1) enables BIM models to be translated into ModelicaBEM models, (2) enables system interface development based on the MVD for thermal simulation, and (3) facilitates the reuse of original BIM data into building energy simulation without an import/export process.
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Translating Building Information Modeling to Building Energy Modeling Using Model View Definition
Directory of Open Access Journals (Sweden)
WoonSeong Jeong
2014-01-01
Full Text Available This paper presents a new approach to translate between Building Information Modeling (BIM and Building Energy Modeling (BEM that uses Modelica, an object-oriented declarative, equation-based simulation environment. The approach (BIM2BEM has been developed using a data modeling method to enable seamless model translations of building geometry, materials, and topology. Using data modeling, we created a Model View Definition (MVD consisting of a process model and a class diagram. The process model demonstrates object-mapping between BIM and Modelica-based BEM (ModelicaBEM and facilitates the definition of required information during model translations. The class diagram represents the information and object relationships to produce a class package intermediate between the BIM and BEM. The implementation of the intermediate class package enables system interface (Revit2Modelica development for automatic BIM data translation into ModelicaBEM. In order to demonstrate and validate our approach, simulation result comparisons have been conducted via three test cases using (1 the BIM-based Modelica models generated from Revit2Modelica and (2 BEM models manually created using LBNL Modelica Buildings library. Our implementation shows that BIM2BEM (1 enables BIM models to be translated into ModelicaBEM models, (2 enables system interface development based on the MVD for thermal simulation, and (3 facilitates the reuse of original BIM data into building energy simulation without an import/export process.
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Models Archive and ModelWeb at NSSDC
Bilitza, D.; Papitashvili, N.; King, J. H.
2002-05-01
In addition to its large data holdings, NASA's National Space Science Data Center (NSSDC) also maintains an archive of space physics models for public use (ftp://nssdcftp.gsfc.nasa.gov/models/). The more than 60 model entries cover a wide range of parameters from the atmosphere, to the ionosphere, to the magnetosphere, to the heliosphere. The models are primarily empirical models developed by the respective model authors based on long data records from ground and space experiments. An online model catalog (http://nssdc.gsfc.nasa.gov/space/model/) provides information about these and other models and links to the model software if available. We will briefly review the existing model holdings and highlight some of its usages and users. In response to a growing need by the user community, NSSDC began to develop web-interfaces for the most frequently requested models. These interfaces enable users to compute and plot model parameters online for the specific conditions that they are interested in. Currently included in the Modelweb system (http://nssdc.gsfc.nasa.gov/space/model/) are the following models: the International Reference Ionosphere (IRI) model, the Mass Spectrometer Incoherent Scatter (MSIS) E90 model, the International Geomagnetic Reference Field (IGRF) and the AP/AE-8 models for the radiation belt electrons and protons. User accesses to both systems have been steadily increasing over the last years with occasional spikes prior to large scientific meetings. The current monthly rate is between 5,000 to 10,000 accesses for either system; in February 2002 13,872 accesses were recorded to the Modelsweb and 7092 accesses to the models archive.
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Anaïs Schaeffer
2012-01-01
By analysing the production of mesons in the forward region of LHC proton-proton collisions, the LHCf collaboration has provided key information needed to calibrate extremely high-energy cosmic ray models. Average transverse momentum (pT) as a function of rapidity loss ∆y. Black dots represent LHCf data and the red diamonds represent SPS experiment UA7 results. The predictions of hadronic interaction models are shown by open boxes (sibyll 2.1), open circles (qgsjet II-03) and open triangles (epos 1.99). Among these models, epos 1.99 shows the best overall agreement with the LHCf data. LHCf is dedicated to the measurement of neutral particles emitted at extremely small angles in the very forward region of LHC collisions. Two imaging calorimeters – Arm1 and Arm2 – take data 140 m either side of the ATLAS interaction point. “The physics goal of this type of analysis is to provide data for calibrating the hadron interaction models – the well-known &...
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Model Manipulation for End-User Modelers
DEFF Research Database (Denmark)
Acretoaie, Vlad
, and transformations using their modeling notation and editor of choice. The VM* languages are implemented via a single execution engine, the VM* Runtime, built on top of the Henshin graph-based transformation engine. This approach combines the benefits of flexibility, maturity, and formality. To simplify model editor......End-user modelers are domain experts who create and use models as part of their work. They are typically not Software Engineers, and have little or no programming and meta-modeling experience. However, using model manipulation languages developed in the context of Model-Driven Engineering often...... requires such experience. These languages are therefore only used by a small subset of the modelers that could, in theory, benefit from them. The goals of this thesis are to substantiate this observation, introduce the concepts and tools required to overcome it, and provide empirical evidence in support...
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Modeling energy-economy interactions using integrated models
International Nuclear Information System (INIS)
Uyterlinde, M.A.
1994-06-01
Integrated models are defined as economic energy models that consist of several submodels, either coupled by an interface module, or embedded in one large model. These models can be used for energy policy analysis. Using integrated models yields the following benefits. They provide a framework in which energy-economy interactions can be better analyzed than in stand-alone models. Integrated models can represent both energy sector technological details, as well as the behaviour of the market and the role of prices. Furthermore, the combination of modeling methodologies in one model can compensate weaknesses of one approach with strengths of another. These advantages motivated this survey of the class of integrated models. The purpose of this literature survey therefore was to collect and to present information on integrated models. To carry out this task, several goals were identified. The first goal was to give an overview of what is reported on these models in general. The second one was to find and describe examples of such models. Other goals were to find out what kinds of models were used as component models, and to examine the linkage methodology. Solution methods and their convergence properties were also a subject of interest. The report has the following structure. In chapter 2, a 'conceptual framework' is given. In chapter 3 a number of integrated models is described. In a table, a complete overview is presented of all described models. Finally, in chapter 4, the report is summarized, and conclusions are drawn regarding the advantages and drawbacks of integrated models. 8 figs., 29 refs
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On the role of model structure in hydrological modeling : Understanding models
Gharari, S.
2016-01-01
Modeling is an essential part of the science of hydrology. Models enable us to formulate what we know and perceive from the real world into a neat package. Rainfall-runoff models are abstract simplifications of how a catchment works. Within the research field of scientific rainfall-runoff modeling,
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Evolution of computational models in BioModels Database and the Physiome Model Repository.
Scharm, Martin; Gebhardt, Tom; Touré, Vasundra; Bagnacani, Andrea; Salehzadeh-Yazdi, Ali; Wolkenhauer, Olaf; Waltemath, Dagmar
2018-04-12
A useful model is one that is being (re)used. The development of a successful model does not finish with its publication. During reuse, models are being modified, i.e. expanded, corrected, and refined. Even small changes in the encoding of a model can, however, significantly affect its interpretation. Our motivation for the present study is to identify changes in models and make them transparent and traceable. We analysed 13734 models from BioModels Database and the Physiome Model Repository. For each model, we studied the frequencies and types of updates between its first and latest release. To demonstrate the impact of changes, we explored the history of a Repressilator model in BioModels Database. We observed continuous updates in the majority of models. Surprisingly, even the early models are still being modified. We furthermore detected that many updates target annotations, which improves the information one can gain from models. To support the analysis of changes in model repositories we developed MoSt, an online tool for visualisations of changes in models. The scripts used to generate the data and figures for this study are available from GitHub https://github.com/binfalse/BiVeS-StatsGenerator and as a Docker image at https://hub.docker.com/r/binfalse/bives-statsgenerator/ . The website https://most.bio.informatik.uni-rostock.de/ provides interactive access to model versions and their evolutionary statistics. The reuse of models is still impeded by a lack of trust and documentation. A detailed and transparent documentation of all aspects of the model, including its provenance, will improve this situation. Knowledge about a model's provenance can avoid the repetition of mistakes that others already faced. More insights are gained into how the system evolves from initial findings to a profound understanding. We argue that it is the responsibility of the maintainers of model repositories to offer transparent model provenance to their users.
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Tvergaard, Viggo
2007-01-01
This special issue constitutes the Proceedings of the IUTAM Symposium on Plasticity at the Micron Scale, held at the Technical University of Denmark, 21-25 May 2006. The purpose of this symposium was to gather a group of leading scientists working in areas of importance to length scale dependent plasticity. This includes work on phenomenological strain gradient plasticity models, studies making use of discrete dislocation models, and even atomic level models. Experimental investigations are central to all this, as all the models focus on developing an improved understanding of real observed phenomena. The opening lecture by Professor N A Fleck, Cambridge University, discussed experimental as well as theoretical approaches. Also, recent results for the surface roughness at grain boundaries were presented based on experiments and crystal plasticity modelling. A number of presentations focused on experiments for metals at a small length scale, e.g. using indenters or a small single crystal compression test. It was found that there are causes of the size effects other than the geometrically necessary dislocations related to strain gradients. Several lectures on scale dependent phenomenological plasticity theories discussed different methods of incorporating the characteristic material length. This included lower order plasticity theories as well as higher order theories, within standard plasticity models or crystal plasticity. Differences in the ways of incorporating higher order boundary conditions were the subject of much discussion. Various methods for discrete dislocation modelling of plastic deformation were used in some of the presentations to obtain a more detailed understanding of length scale effects in metals. This included large scale computations for dislocation dynamics as well as new statistical mechanics approaches to averaging of dislocation plasticity. Furthermore, at a somewhat larger length scale, applications of scale dependent plasticity to
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DEFF Research Database (Denmark)
Rasmussen, Henrik Koblitz; Hassager, Ole; Bach, Anders
2004-01-01
The transient (e.g. start up of) elongational viscosity of three low-density polyethylene (LDPE) melts (BASF Lupolen 1810H, 1840D and 3020D) was measured using a filament stretching rheometer (FSR) capable of measuring at elevated temperatures. The transient uni-axial elongational viscosity showe...
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Model documentation report: Transportation sector model of the National Energy Modeling System
Energy Technology Data Exchange (ETDEWEB)
1994-03-01
This report documents the objectives, analytical approach and development of the National Energy Modeling System (NEMS) Transportation Model (TRAN). The report catalogues and describes the model assumptions, computational methodology, parameter estimation techniques, model source code, and forecast results generated by the model. This document serves three purposes. First, it is a reference document providing a detailed description of TRAN for model analysts, users, and the public. Second, this report meets the legal requirements of the Energy Information Administration (EIA) to provide adequate documentation in support of its statistical and forecast reports (Public Law 93-275, 57(b)(1)). Third, it permits continuity in model development by providing documentation from which energy analysts can undertake model enhancements, data updates, and parameter refinements.
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Zhang, Xin-Guo; Liu, Jin-Wen; Tang, Peng; Liu, Zi-Yu; Guo, Guang-Jun; Sun, Qiao-Yun; Yin, Jian-Jun
2018-05-01
Adenosine deaminase (ADA) is an enzyme widely distributed from bacteria to humans. ADA is known as a potential therapeutic target for the treatment of lymphoproliferative disorders and cancer. Endophytes are endosymbionts, often bacteria or fungi, which live within plant tissues and internal organs or intercellular space. Endophytes have a broad variety of bioactive metabolites that are used for the identification of novel natural compounds. Here, 54 morphologically distinct endophyte strains were isolated from six plants such as Peganum harmala Linn., Rheum officinale Baill., Gentiana macrophylla Pall., Radix stephaniae tetrandrae, Myrrha, and Equisetum hyemale Linn. The isolated strains were used for the search of ADA inhibitors that resulted in the identification of the strain with the highest inhibition activity, Aspergillus niger sp. Four compounds were isolated from this strain using three-step chromatography procedure, and compound 2 was determined as the compound with the highest inhibition activity of ADA. Based on the results of 1 H and 13 C NMR spectroscopies, compound 2 was identified as 3-(4-nitrophenyl)-5-phenyl isoxazole. We showed that compound 2 was a new uncompetitive inhibitor of ADA with high cytotoxic effect on HepG2 and SMCC-7721 cells (the IC 50 values were 0.347 and 0.380 mM, respectively). These results suggest that endophyte strains serve as promising sources for the identification of ADA inhibitors, and compound 2 could be an effective drug in the cancer treatment.
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Zhao, Daqiu; Xia, Xing; Wei, Mengran; Sun, Jing; Meng, Jiasong; Tao, Jun
2017-12-01
microRNAs (miRNAs) play critical regulatory roles in plant growth and development. In the present study, the function of herbaceous peony ( Paeonia lactiflora Pall.) miR156e-3p in the regulation of color formation has been investigated. Firstly, P. lactiflora miR156e-3p precursor sequence (pre-miR156e-3p) was isolated. Subsequently, the overexpression vector of pre-miR156e-3p was constructed and transformed into Arabidopsis thaliana . Moreover, the medium screening, GUS staining, polymerase chain reaction (PCR) of the GUS region and real-time quantitative PCR (qRT-PCR) of miR156e-3p all confirmed that the purpose gene had been successfully transferred into Arabidopsis plants and expressed, which resulted in apparent purple lateral branches. And this change in color was caused by the improved anthocyanin accumulation. In addition, expression analysis had shown that the level of miR156e-3p transcript was increased, while transcription level of target gene squamosa promoter binding protein-like gene ( SPL1 ), encoding SPL transcription factor that negatively regulated anthocyanin accumulation, was repressed in miR156e-3p-overexpressing transgenic plants, and its downstream gene dihydroflavonol 4-reductase gene ( DFR ) that was directly involved in anthocyanin biosynthesis was strongly expressed, which resulted in anthocyanin accumulation of Arabidopsis lateral branches. These findings would improve the understanding of miRNAs regulation of color formation in P. lactiflora .