WorldWideScience

Sample records for model main effects

  1. Wildfire Risk Main Model

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — The model combines three modeled fire behavior parameters (rate of spread, flame length, crown fire potential) and one modeled ecological health measure (fire regime...

  2. [Analysis of genetic models and gene effects on main agronomy characters in rapeseed].

    Science.gov (United States)

    Li, J; Qiu, J; Tang, Z; Shen, L

    1992-01-01

    According to four different genetic models, the genetic patterns of 8 agronomy traits were analysed by using the data of 24 generations which included positive and negative cross of 81008 x Tower, both of the varieties are of good quality. The results showed that none of 8 characters could fit in with additive-dominance models. Epistasis was found in all of these characters, and it has significant effect on generation means. Seed weight/plant and some other main yield characters are controlled by duplicate interaction genes. The interaction between triple genes or multiple genes needs to be utilized in yield heterosis.

  3. Fragmentation Main Model

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — The fragmentation model combines patch size and patch continuity with diversity of vegetation types per patch and rarity of vegetation types per patch. A patch was...

  4. NCACO-score: An effective main-chain dependent scoring function for structure modeling

    Directory of Open Access Journals (Sweden)

    Dong Xiaoxi

    2011-05-01

    Full Text Available Abstract Background Development of effective scoring functions is a critical component to the success of protein structure modeling. Previously, many efforts have been dedicated to the development of scoring functions. Despite these efforts, development of an effective scoring function that can achieve both good accuracy and fast speed still presents a grand challenge. Results Based on a coarse-grained representation of a protein structure by using only four main-chain atoms: N, Cα, C and O, we develop a knowledge-based scoring function, called NCACO-score, that integrates different structural information to rapidly model protein structure from sequence. In testing on the Decoys'R'Us sets, we found that NCACO-score can effectively recognize native conformers from their decoys. Furthermore, we demonstrate that NCACO-score can effectively guide fragment assembly for protein structure prediction, which has achieved a good performance in building the structure models for hard targets from CASP8 in terms of both accuracy and speed. Conclusions Although NCACO-score is developed based on a coarse-grained model, it is able to discriminate native conformers from decoy conformers with high accuracy. NCACO is a very effective scoring function for structure modeling.

  5. THE INTEGRATION MODEL ASEAN+1: THE MAIN NORMS OF AGREEMENTS AND EFFECT ON FOREIGN ECONOMIC TIES

    Directory of Open Access Journals (Sweden)

    Г М Костюнина

    2017-12-01

    Full Text Available The aim of this research is a comparative analysis of the provisions of free trade agreements signed by ASEAN with dialogue countries and the East Asia Summit partners - China, Japan, the Republic of Korea, India, Australia and New Zealand. The author's thesis is that, in our opinion, the final effect of participation in the free trade zone for the national economy depends on such factors as the volume of mutual trade, the degree of economic interde-pendence, the level of customs duties rates at the date of signing the agreement, the volume of the mutual market, geographical proximity. The higher the role of these factors, the greater the effect of trade creation is received by the participating states. The basis of the research methodology is the understanding of regional integration agreements as a multifactor instrument of trade policy in various countries of the world that facilitates the liberalization of international trade in general and the regional trade in particular, enhancing the participation of partner states in the international division of labor and stimulating the dynamics of their economic development. Such agreements are considered as a system that includes a set of elements that interact with elements of other systems. Such interaction is considered taking into account the specific purpose of each of the elements, and also taking into account the factors of the stability of the development of each system. In carry-ing out this study, the author has used such methods as the method of comparative analysis, which makes it possible to identify the specifics of the participation of ASEAN countries in free trade zones; methods of statistical analysis and political forecasting that provide an opportunity to identify legal norms of integra-tion agreements on the ASEAN + 1 model; as well as a logical conceptual analysis that allows to present a full picture of the ASEAN integration policy. The author analyses norms for regulating the

  6. Modelling the effect of coating on the stresses and microstructure evolution in chill casting of wind turbine main shafts

    DEFF Research Database (Denmark)

    Sonne, Mads Rostgaard; Thorborg, J.; Hattel, Jesper Henri

    2017-01-01

    The purpose of the present work is to quantify the effect of the inside coating on chills for casting of large wind turbine main shafts with respect to the evolution of internal stresses. These are known to affect the lifetime of the chills, and this is a major cost for the foundries today. Simul......, it is concluded that the material quality obtained from casting the main shafts in chills (and hence the performance of the part) is still much better than for sand casting, even though a very thick layer of coating is applied. Copyright © 2017 John Wiley & Sons, Ltd....... in the simulations. The outcome is validated by comparisons with samples taken out from a critical region of main shafts cast in sand and in chills. The results reveal minor reductions in the maximum principal stresses on the inner and outer surfaces of the chill of 3.1% and 18.5%, respectively, from changing...

  7. Effects of blast wave to main steam piping under high energy line break condition by TNT model

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Seung Hyun; Lee, Eung Seok; Chang, Yoon Suk [Kyung Hee University, Yongin (Korea, Republic of)

    2016-05-15

    The aim of this study is to examine effect of the blast wave according to pipe break position through FE (Finite Element) analyses. If HELB (High Energy Line Break) accident occurs in nuclear power plants, not only environmental effect such as release of radioactive material but also secondary structural defects should be considered. Sudden pipe rupture causes ejection of high temperature and pressure fluid, which acts as a blast wave around the break location. The blast wave caused by the HELB has a possibility to induce structural defects around the components such as safe-related injection pipes and other structures.

  8. Portland, Maine Coastal Digital Elevation Model

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA's National Geophysical Data Center (NGDC) is building high-resolution digital elevation models (DEMs) for select U.S. coastal regions. These integrated...

  9. Effects of Secondary Circuit Modeling on Results of Pressurized Water Reactor Main Steam Line Break Benchmark Calculations with New Coupled Code TRAB-3D/SMABRE

    International Nuclear Information System (INIS)

    Daavittila, Antti; Haemaelaeinen, Anitta; Kyrki-Rajamaeki, Riitta

    2003-01-01

    All of the three exercises of the Organization for Economic Cooperation and Development/Nuclear Regulatory Commission pressurized water reactor main steam line break (PWR MSLB) benchmark were calculated at VTT, the Technical Research Centre of Finland. For the first exercise, the plant simulation with point-kinetic neutronics, the thermal-hydraulics code SMABRE was used. The second exercise was calculated with the three-dimensional reactor dynamics code TRAB-3D, and the third exercise with the combination TRAB-3D/SMABRE. VTT has over ten years' experience of coupling neutronic and thermal-hydraulic codes, but this benchmark was the first time these two codes, both developed at VTT, were coupled together. The coupled code system is fast and efficient; the total computation time of the 100-s transient in the third exercise was 16 min on a modern UNIX workstation. The results of all the exercises are similar to those of the other participants. In order to demonstrate the effect of secondary circuit modeling on the results, three different cases were calculated. In case 1 there is no phase separation in the steam lines and no flow reversal in the aspirator. In case 2 the flow reversal in the aspirator is allowed, but there is no phase separation in the steam lines. Finally, in case 3 the drift-flux model is used for the phase separation in the steam lines, but the aspirator flow reversal is not allowed. With these two modeling variations, it is possible to cover a remarkably broad range of results. The maximum power level reached after the reactor trip varies from 534 to 904 MW, the range of the time of the power maximum being close to 30 s. Compared to the total calculated transient time of 100 s, the effect of the secondary side modeling is extremely important

  10. Predicting water main failures using Bayesian model averaging and survival modelling approach

    International Nuclear Information System (INIS)

    Kabir, Golam; Tesfamariam, Solomon; Sadiq, Rehan

    2015-01-01

    To develop an effective preventive or proactive repair and replacement action plan, water utilities often rely on water main failure prediction models. However, in predicting the failure of water mains, uncertainty is inherent regardless of the quality and quantity of data used in the model. To improve the understanding of water main failure, a Bayesian framework is developed for predicting the failure of water mains considering uncertainties. In this study, Bayesian model averaging method (BMA) is presented to identify the influential pipe-dependent and time-dependent covariates considering model uncertainties whereas Bayesian Weibull Proportional Hazard Model (BWPHM) is applied to develop the survival curves and to predict the failure rates of water mains. To accredit the proposed framework, it is implemented to predict the failure of cast iron (CI) and ductile iron (DI) pipes of the water distribution network of the City of Calgary, Alberta, Canada. Results indicate that the predicted 95% uncertainty bounds of the proposed BWPHMs capture effectively the observed breaks for both CI and DI water mains. Moreover, the performance of the proposed BWPHMs are better compare to the Cox-Proportional Hazard Model (Cox-PHM) for considering Weibull distribution for the baseline hazard function and model uncertainties. - Highlights: • Prioritize rehabilitation and replacements (R/R) strategies of water mains. • Consider the uncertainties for the failure prediction. • Improve the prediction capability of the water mains failure models. • Identify the influential and appropriate covariates for different models. • Determine the effects of the covariates on failure

  11. Regional Ocean Modeling System (ROMS): Main Hawaiian Islands: Data Assimilating

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Regional Ocean Modeling System (ROMS) 3-day, 3-hourly data assimilating hindcast for the region surrounding the main Hawaiian islands at approximately 4-km...

  12. Regional Ocean Modeling System (ROMS): Main Hawaiian Islands

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Regional Ocean Modeling System (ROMS) 7-day, 3-hourly forecast for the region surrounding the main Hawaiian islands at approximately 4-km resolution. While...

  13. ANS main control complex three-dimensional computer model development

    International Nuclear Information System (INIS)

    Cleaves, J.E.; Fletcher, W.M.

    1993-01-01

    A three-dimensional (3-D) computer model of the Advanced Neutron Source (ANS) main control complex is being developed. The main control complex includes the main control room, the technical support center, the materials irradiation control room, computer equipment rooms, communications equipment rooms, cable-spreading rooms, and some support offices and breakroom facilities. The model will be used to provide facility designers and operations personnel with capabilities for fit-up/interference analysis, visual ''walk-throughs'' for optimizing maintain-ability, and human factors and operability analyses. It will be used to determine performance design characteristics, to generate construction drawings, and to integrate control room layout, equipment mounting, grounding equipment, electrical cabling, and utility services into ANS building designs. This paper describes the development of the initial phase of the 3-D computer model for the ANS main control complex and plans for its development and use

  14. Integrated Main Propulsion System Performance Reconstruction Process/Models

    Science.gov (United States)

    Lopez, Eduardo; Elliott, Katie; Snell, Steven; Evans, Michael

    2013-01-01

    The Integrated Main Propulsion System (MPS) Performance Reconstruction process provides the MPS post-flight data files needed for postflight reporting to the project integration management and key customers to verify flight performance. This process/model was used as the baseline for the currently ongoing Space Launch System (SLS) work. The process utilizes several methodologies, including multiple software programs, to model integrated propulsion system performance through space shuttle ascent. It is used to evaluate integrated propulsion systems, including propellant tanks, feed systems, rocket engine, and pressurization systems performance throughout ascent based on flight pressure and temperature data. The latest revision incorporates new methods based on main engine power balance model updates to model higher mixture ratio operation at lower engine power levels.

  15. Solar Luminosity on the Main Sequence, Standard Model and Variations

    Science.gov (United States)

    Ayukov, S. V.; Baturin, V. A.; Gorshkov, A. B.; Oreshina, A. V.

    2017-05-01

    Our Sun became Main Sequence star 4.6 Gyr ago according Standard Solar Model. At that time solar luminosity was 30% lower than current value. This conclusion is based on assumption that Sun is fueled by thermonuclear reactions. If Earth's albedo and emissivity in infrared are unchanged during Earth history, 2.3 Gyr ago oceans had to be frozen. This contradicts to geological data: there was liquid water 3.6-3.8 Gyr ago on Earth. This problem is known as Faint Young Sun Paradox. We analyze luminosity change in standard solar evolution theory. Increase of mean molecular weight in the central part of the Sun due to conversion of hydrogen to helium leads to gradual increase of luminosity with time on the Main Sequence. We also consider several exotic models: fully mixed Sun; drastic change of pp reaction rate; Sun consisting of hydrogen and helium only. Solar neutrino observations however exclude most non-standard solar models.

  16. Effect of main stream void distribution on cavitating hydrofoil

    International Nuclear Information System (INIS)

    Ito, J.

    1993-01-01

    For the safety analysis of a loss of coolant accident in a pressurized water reactor, it is important to establish an analytical method which predicts the pump performance under gas-liquid two-phase flow condition. J.H. Kim briefly reviewed several major two-phase flow pump models, and discussed the parameters that could significantly affect two-phase pump behavior. The parameter pointed out to be of the most importance is void distribution at the pump inlet. This says that the pipe bend near the pump inlet makes the void distribution at the pump inlet nonuniform, and this matter can have a significant effect on the impeller blade performance. This paper proposes an analytical method of solution for a partially cavitating hydrofoil placed in the main stream of incompressible homogeneous bubbly two-phase flow conditions whose void fraction is exponentially distributed normal to chordline. The paper clarifies the effect of main stream void distribution parameter on the partially cavitating hydrofoil characteristics

  17. ANALYSIS AND SIMULATION OF MAIN MAGNET TRANSMISSION LINE EFFECT

    Energy Technology Data Exchange (ETDEWEB)

    ZHANG,W.; MARNERIS, I.; SANDBERG, J.

    2007-06-25

    A main magnet chain forms a pair of transmission lines. Pulse-reflection-caused voltage and current differentiation throughout the magnet chain can have adverse effect on main magnet field quality. This effect is associated with magnet system configuration, coupling efficiency, and parasitic parameters. A better understanding of this phenomenon will help us in new design and existing system upgrade. In this paper, we exam the transmission line effect due to different input functions as well as configuration, coupling, and other parameters.

  18. The Livingstone Model of a Main Propulsion System

    Science.gov (United States)

    Bajwa, Anupa; Sweet, Adam; Korsmeyer, David (Technical Monitor)

    2003-01-01

    Livingstone is a discrete, propositional logic-based inference engine that has been used for diagnosis of physical systems. We present a component-based model of a Main Propulsion System (MPS) and say how it is used with Livingstone (L2) in order to implement a diagnostic system for integrated vehicle health management (IVHM) for the Propulsion IVHM Technology Experiment (PITEX). We start by discussing the process of conceptualizing such a model. We describe graphical tools that facilitated the generation of the model. The model is composed of components (which map onto physical components), connections between components and constraints. A component is specified by variables, with a set of discrete, qualitative values for each variable in its local nominal and failure modes. For each mode, the model specifies the component's behavior and transitions. We describe the MPS components' nominal and fault modes and associated Livingstone variables and data structures. Given this model, and observed external commands and observations from the system, Livingstone tracks the state of the MPS over discrete time-steps by choosing trajectories that are consistent with observations. We briefly discuss how the compiled model fits into the overall PITEX architecture. Finally we summarize our modeling experience, discuss advantages and disadvantages of our approach, and suggest enhancements to the modeling process.

  19. Main and interaction effects of extrusion temperature and usage ...

    African Journals Online (AJOL)

    ali

    2012-10-30

    Oct 30, 2012 ... The main and interaction effects of three extrusion ... oil extraction and allow the use of a homegrown protein supplement in the .... Statistical analysis. The main and .... acceptable level of antitrypsin factor is 4 mg/g; this level.

  20. Energy modeling: nuclear energy as China's main energy after 2040

    International Nuclear Information System (INIS)

    Guo Xingqu

    1987-01-01

    According to the energy modeling and the strategic forecast of China's economic development and population, the energy demand in China in the coming century has been calculated yearly by computer simulation. It is shown by the calculation results that the primary energy consumption in 2050 will be 3.37-4.25 times as that of 2000. The fossil energy will still be the main energy during the early stage of 21st century, but it will be cut down rapidly since 2020s as its annual consumption is increased to 1.656-2.044 x 10 9 tce/a. Because the fossil fuel ressources in China are limited, more and more fossil fuel will be mainly turned to chemical products, and the environmental pollution will be serious if we still use the fossil as a main fuel widely. The amount of renewable energy will be increasing, but its share in the primary energy consumption will be cut down from 36% to about 20% during the first half of next century and then will maintain this portion. In this case, the nuclear energy will be developed rapidly during the early stage of next century and will become the main energy since 2040. The methodology of energy forecast has also been reviewed

  1. Modelling Dynamics of Main Economic Indicators of an Enterprise

    Directory of Open Access Journals (Sweden)

    Sherstennykov Yurii V.

    2014-03-01

    Full Text Available The article develops an economic and mathematical model of dynamics of main economic indicators of an enterprise, reflected in six book-keeping accounts with consideration of logistics and interrelation with current market characteristics and needs of products consumers. It applies this model for a quantitative study of influence of an advertising campaign and seasonality upon quantitative indicators of economic activity of the enterprise. The enterprise operation programme includes internal financial and economic procedures, which ensure the production process, and also connection with suppliers and buyers (customers. When setting different initial conditions, it is possible to trace transitional processes and enterprise entering (under favourable conditions the stationary mode of operation or its laying-off (in case of insufficiency of circulating funds. The developed model contains many parameters, which allow not only study of dependence of enterprise operation on alteration of one of them but also optimisation of economic conditions of functioning.

  2. Main principles of developing exploitation models of semiconductor devices

    Science.gov (United States)

    Gradoboev, A. V.; Simonova, A. V.

    2018-05-01

    The paper represents primary tasks, solutions of which allow to develop the exploitation modes of semiconductor devices taking into account complex and combined influence of ionizing irradiation and operation factors. The structure of the exploitation model of the semiconductor device is presented, which is based on radiation and reliability models. Furthermore, it was shown that the exploitation model should take into account complex and combine influence of various ionizing irradiation types and operation factors. The algorithm of developing the exploitation model of the semiconductor devices is proposed. The possibility of creating the radiation model of Schottky barrier diode, Schottky field-effect transistor and Gunn diode is shown based on the available experimental data. The basic exploitation model of IR-LEDs based upon double AlGaAs heterostructures is represented. The practical application of the exploitation models will allow to output the electronic products with guaranteed operational properties.

  3. COMPARATIVE STUDY ON MAIN SOLVENCY ASSESSMENT MODELS FOR INSURANCE FIELD

    Directory of Open Access Journals (Sweden)

    Daniela Nicoleta SAHLIAN

    2015-07-01

    Full Text Available During the recent financial crisis of insurance domain, there were imposed new aspects that have to be taken into account concerning the risks management and surveillance activity. The insurance societies could develop internal models in order to determine the minimum capital requirement imposed by the new regulations that are to be adopted on 1 January 2016. In this respect, the purpose of this research paper is to offer a real presentation and comparing with the main solvency regulation systems used worldwide, the accent being on their common characteristics and current tendencies. Thereby, we would like to offer a better understanding of the similarities and differences between the existent solvency regimes in order to develop the best regime of solvency for Romania within the Solvency II project. The study will show that there are clear differences between the existent Solvency I regime and the new approaches based on risk and will also point out the fact that even the key principles supporting the new solvency regimes are convergent, there are a lot of approaches for the application of these principles. In this context, the question we would try to find the answer is "how could the global solvency models be useful for the financial surveillance authority of Romania for the implementation of general model and for the development of internal solvency models according to the requirements of Solvency II" and "which would be the requirements for the implementation of this type of approach?". This thing makes the analysis of solvency models an interesting exercise.

  4. Main features of the proposed NCRP respiratory tract model

    International Nuclear Information System (INIS)

    Phalen, R.F.; Fisher, G.L.; Moss, O.R.; Schlesinger, R.B.; Swift, D.L.

    1991-01-01

    The proposed NCRP respiratory tract dosimetry model regions include the naso-oro-pharyngo-laryngeal (NOPL), the tracheobronchial (TB), the pulmonary (P), and the lymph nodes (LN). Input aerosol concentrations are derived from a consideration of particle-size-dependent inspirability. Particle deposition in the respiratory tract is modelled using the mechanisms of inertial impaction, sedimentation and diffusion. The rates of absorption of particles, and transport to the blood, have been derived from clearance data from people and laboratory animals. The effect of body growth on particle deposition is considered. Particle clearance rates are assumed to be independent of age. The proposed respiratory tract model differs significantly from the 1966 Task Group Model in that (1) inspirability is considered; (2) new sub-regions of the respiratory tract are considered; (3) absorption of materials by the blood is treated in a more sophisticated fashion; and (4) body size (and thus age) is taken into account. (author)

  5. Two-Level Designs to Estimate All Main Effects and Two-Factor Interactions

    NARCIS (Netherlands)

    Eendebak, P.T.; Schoen, E.D.

    2017-01-01

    We study the design of two-level experiments with N runs and n factors large enough to estimate the interaction model, which contains all the main effects and all the two-factor interactions. Yet, an effect hierarchy assumption suggests that main effect estimation should be given more prominence

  6. Main considerations for modelling a station blackout scenario with trace

    International Nuclear Information System (INIS)

    Querol, Andrea; Turégano, Jara; Lorduy, María; Gallardo, Sergio; Verdú, Gumersindo

    2017-01-01

    In the nuclear safety field, the thermal hydraulic phenomena that take place during an accident in a nuclear power plant is of special importance. One of the most studied accidents is the Station BlackOut (SBO). The aim of the present work is the analysis of the PKL integral test facility nodalization using the thermal-hydraulic code TRACE5 to reproduce a SBO accidental scenario. The PKL facility reproduces the main components of the primary and secondary systems of its reference nuclear power plant (Philippsburg II). The results obtained with different nodalization have been compared: 3D vessel vs 1D vessel, Steam Generator (SG) modelling using PIPE or TEE components and pressurizer modelling with PIPE or PRIZER components. Both vessel nodalization (1D vessel and 3D vessel) reproduce the physical phenomena of the experiment. However, there are significant discrepancies between them. The appropriate modelling of the SG is also relevant in the results. Regarding the other nodalization (PIPE or TEE components for SG and PIPE or PRIZER components for pressurizer), do not produce relevant differences in the results. (author)

  7. Main considerations for modelling a station blackout scenario with trace

    Energy Technology Data Exchange (ETDEWEB)

    Querol, Andrea; Turégano, Jara; Lorduy, María; Gallardo, Sergio; Verdú, Gumersindo, E-mail: anquevi@upv.es, E-mail: jaturna@upv.es, E-mail: maloral@upv.es, E-mail: sergalbe@iqn.upv.es, E-mail: gverdu@iqn.upv.es [Instituto Universitario de Seguridad Industrial, Radiofísica y Medioambiental (ISIRYM), Universitat Politècnica de València (Spain)

    2017-07-01

    In the nuclear safety field, the thermal hydraulic phenomena that take place during an accident in a nuclear power plant is of special importance. One of the most studied accidents is the Station BlackOut (SBO). The aim of the present work is the analysis of the PKL integral test facility nodalization using the thermal-hydraulic code TRACE5 to reproduce a SBO accidental scenario. The PKL facility reproduces the main components of the primary and secondary systems of its reference nuclear power plant (Philippsburg II). The results obtained with different nodalization have been compared: 3D vessel vs 1D vessel, Steam Generator (SG) modelling using PIPE or TEE components and pressurizer modelling with PIPE or PRIZER components. Both vessel nodalization (1D vessel and 3D vessel) reproduce the physical phenomena of the experiment. However, there are significant discrepancies between them. The appropriate modelling of the SG is also relevant in the results. Regarding the other nodalization (PIPE or TEE components for SG and PIPE or PRIZER components for pressurizer), do not produce relevant differences in the results. (author)

  8. Main and interaction effects of extrusion temperature and usage ...

    African Journals Online (AJOL)

    The extruded full fat soybean (EFFSB) may be used in diet to satisfy the energy and protein requirements of fast growing broiler chickens. The main and interaction effects of three extrusion temperatures and two dietary levels of FFSB were studied on the performance, physiological enzymes and blood metabolites of broiler ...

  9. Overview of collective effects in the NLC main damping rings

    International Nuclear Information System (INIS)

    Wolski, A.; Santis, S. de

    2002-01-01

    The present design for the NLC Main Damping Rings (MDRs) meets the specifications for acceptance and extracted emittance, in the limit of zero current. However, the relatively large bunch charge and moderate energy mean that a variety of collective effects can impact the beam dynamics, leading to loss of stability or increase of equilibrium emittance. These effects include intrabeam scattering, impedance from numerous sources, fast ion instability, and (in the positron ring) electron cloud. In this note, we survey the expected impact on damping ring performance from each of a number of collective effects, and discuss the priorities for future studies in this area

  10. Domino effect in chemical accidents: main features and accident sequences

    OpenAIRE

    Casal Fàbrega, Joaquim; Darbra Roman, Rosa Maria

    2010-01-01

    The main features of domino accidents in process/storage plants and in the transportation of hazardous materials were studied through an analysis of 225 accidents involving this effect. Data on these accidents, which occurred after 1961, were taken from several sources. Aspects analyzed included the accident scenario, the type of accident, the materials involved, the causes and consequences and the most common accident sequences. The analysis showed that the most frequent causes a...

  11. Item 141 Radiotherapy. Radiobiological notions; main secondary effects

    International Nuclear Information System (INIS)

    Azria, David; Dubois, Jean-Bernard

    2006-11-01

    This document first gives definitions of ionizing radiations, photons, electrons and Gray (as a dose unit). It describes the mechanisms of action of ionizing radiations: physical, chemical, cellular actions, actions on tissues. It analyses and discusses the factors influencing the effects of radiations: intrinsic radio-sensitivity, cellular cycle, oxygen, time (session fractioning and organisation in time), and dose. The different types of radiotherapy are then presented: external radiotherapy, brachytherapy, radio-immunotherapy of internal radiotherapy. It discusses tissues tolerance doses and doses required to sterilize tumours, and discusses the various and main secondary effects: stochastic secondary effects and deterministic secondary effects. A table indicates possible early and late reactions for different organs (skin, lung, brain, medulla, nerves, oesophagus, heart, pancreas, stomach, liver, intestine, kidney, bladder, rectum, ENT, or eye's lens)

  12. Estimates of dispersive effects in a bent NLC Main Linac

    International Nuclear Information System (INIS)

    Syphers, Michael; Michelotti, Leo

    2000-01-01

    An alternative being considered for the Next Linear Collider (NLC) is not to tunnel in a straight line but to bend the Main Linac into an arc so as to follow a gravitational equipotential. The authors begin here an examination of the effects that this would have on vertical dispersion, with its attendant consequences on synchrotron radiation and emittance growth by looking at two scenarios: a gentle continuous bending of the beam to follow an equipotential surface, and an introduction of sharp bends at a few sites in the linac so as to reduce the maximum sagitta produced

  13. Estimates of dispersive effects in a bent NLC main linac

    OpenAIRE

    Syphers, M.; Michelotti, L.

    2000-01-01

    An alternative being considered for the Next Linear Collider (NLC) is not to tunnel in a straight line but to bend the Main Linac into an arc so as to follow an equipotential. We begin here an examination of the effects that this would have on vertical dispersion, with its attendant consequences on synchrotron radiation and emittance growth by looking at two scenarios: a gentle continuous bending of the beam to follow an equipotential surface, and an introduction of sharp bends at a few sites...

  14. Domino effect in chemical accidents: main features and accident sequences.

    Science.gov (United States)

    Darbra, R M; Palacios, Adriana; Casal, Joaquim

    2010-11-15

    The main features of domino accidents in process/storage plants and in the transportation of hazardous materials were studied through an analysis of 225 accidents involving this effect. Data on these accidents, which occurred after 1961, were taken from several sources. Aspects analyzed included the accident scenario, the type of accident, the materials involved, the causes and consequences and the most common accident sequences. The analysis showed that the most frequent causes are external events (31%) and mechanical failure (29%). Storage areas (35%) and process plants (28%) are by far the most common settings for domino accidents. Eighty-nine per cent of the accidents involved flammable materials, the most frequent of which was LPG. The domino effect sequences were analyzed using relative probability event trees. The most frequent sequences were explosion→fire (27.6%), fire→explosion (27.5%) and fire→fire (17.8%). Copyright © 2010 Elsevier B.V. All rights reserved.

  15. Understanding, modeling, and improving main-memory database performance

    OpenAIRE

    Manegold, S.

    2002-01-01

    textabstractDuring the last two decades, computer hardware has experienced remarkable developments. Especially CPU (clock-)speed has been following Moore's Law, i.e., doubling every 18 months; and there is no indication that this trend will change in the foreseeable future. Recent research has revealed that database performance, even with main-memory based systems, can hardly benefit from the ever increasing CPU power. The reason for this is that the performance of other hardware components h...

  16. Effects of magnetic fields on main sequence stars

    International Nuclear Information System (INIS)

    Hubbard, E.N.

    1981-01-01

    A number of effects of low to medium strength ( 2 /8π) magnetic field pressure term so that the only effect of such a field may come from its inhibiting convection in the core. Isochrones of both convective and radiative core models of 2-5 M are presented. In the deep envelope, mixing of partially nuclear processed material driven by rising and falling magnetic flux tubes may be seen. The effects of this mixing will be brought to the surface during the deep convection phase of the star's tenure as a red giant. This model is used to predict a signature for magnetic mixing based on the CNO isotope and abundance ratios. In the outer envelope the gas pressure is low enough that one might expect to see a perturbation of the stellar structure due to the magnetic field pressure itself. This perturbation is calculated under several physical models for intermediate and high mass stars and it is determined that sufficient magnetic field energy may be available in the outer envelope to expand a star by about 20% over its unperturbed radius. Finally the evidence for the existence of non-magnetic neutron stars is considered, concluding that while no non-magnetic neutron stars have ever been positively identified, there is no evidence that prevents the existence of at least as many non-magnetic as magnetic neutron stars

  17. CAA modeling of helicopter main rotor in hover

    Directory of Open Access Journals (Sweden)

    Kusyumov Alexander N.

    2017-01-01

    Full Text Available In this work rotor aeroacoustics in hover is considered. Farfield observers are used and the nearfield flow parameters are obtained using the in house HMB and commercial Fluent CFD codes (identical hexa-grids are used for both solvers. Farfield noise at a remote observer position is calculated at post processing stage using FW–H solver implemented in Fluent and HMB. The main rotor of the UH-1H helicopter is considered as a test case for comparison to experimental data. The sound pressure level is estimated for different rotor blade collectives and observation angles.

  18. CAA modeling of helicopter main rotor in hover

    Science.gov (United States)

    Kusyumov, Alexander N.; Mikhailov, Sergey A.; Batrakov, Andrey S.; Kusyumov, Sergey A.; Barakos, George

    In this work rotor aeroacoustics in hover is considered. Farfield observers are used and the nearfield flow parameters are obtained using the in house HMB and commercial Fluent CFD codes (identical hexa-grids are used for both solvers). Farfield noise at a remote observer position is calculated at post processing stage using FW-H solver implemented in Fluent and HMB. The main rotor of the UH-1H helicopter is considered as a test case for comparison to experimental data. The sound pressure level is estimated for different rotor blade collectives and observation angles.

  19. Digital Elevation Models (DEMs) for the main 8 Hawaiian Islands

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Digital elevation model (DEM) data are arrays of regularly spaced elevation values referenced horizontally either to a Universal Transverse Mercator (UTM) projection...

  20. Contact condensation effects in the main coolant pipe

    International Nuclear Information System (INIS)

    Haefner, W.; Fischer, K.

    1990-01-01

    Contact condensation effects may occur in a pressurized water reactor (PWR) after a loss of coolant accident (LOCA) when emergency core cooling (ECC) water is injected contact with escaping steam which is generated within the core. The condensation which takes place may cause a sudden depressurization leading to the formation of water slugs. The interaction between the transient condensation and the inertia of the flow may also result in large amplitude flow and pressure oscillations. These contact condensation effects are of great importance for the mass flow distribution and the coolant water supply to the reactor core. To examine those complex processes, large computer codes are necessary. The development and verification of analytical models requires greatly simplified flow boundary conditions from experiments and a sufficiently large base of experimental data. Separate models have been developed for interfacial exchange of mass, momentum and energy with respect to the associated flow regime. Therefore, an adequate description of the condensation process requires the modeling of two different topics: the prediction of the flow regime and the calculation of the interfacial exchange. (author)

  1. Main features of nucleation in model solutions of oral cavity

    Science.gov (United States)

    Golovanova, O. A.; Chikanova, E. S.; Punin, Yu. O.

    2015-05-01

    The regularities of nucleation in model solutions of oral cavity have been investigated, and the induction order and constants have been determined for two systems: saliva and dental plaque fluid (DPF). It is shown that an increase in the initial supersaturation leads to a transition from the heterogeneous nucleation of crystallites to a homogeneous one. Some additives are found to enhance nucleation: HCO{3/-} > C6H12O6 > F-, while others hinder this process: protein (casein) > Mg2+. It is established that crystallization in DPF occurs more rapidly and the DPF composition is favorable for the growth of small (52.6-26.1 μm) crystallites. On the contrary, the conditions implemented in the model saliva solution facilitate the formation of larger (198.4-41.8 μm) crystals.

  2. Leaf area prediction models for Tsuga canadensis in Maine

    Science.gov (United States)

    Laura S. Kenefic; R.S. Seymour

    1999-01-01

    Tsuga canadensis (L.) Carr. (eastern hemlock) is a common species throughout the Acadian forest. Studies of leaf area and growth efficiency in this forest type have been limited by the lack of equations to predict leaf area of this species. We found that sapwood area was an effective leaf area surrogate in T. canadensis, though...

  3. The Main Cognitive Model of Visual Recognition: Contour Recognition

    OpenAIRE

    Chen, YongHong

    2017-01-01

    In this paper, we will study the following pattern recognition problem: Every pattern is a 3-dimensional graph, its surface can be split up into some regions, every region is composed of the pixels with the approximately same colour value and the approximately same depth value that is distance to eyes, and there may also be some contours, e.g., literal contours, on a surface of every pattern. For this problem we reveal the inherent laws. Moreover, we establish a cognitive model to reflect the...

  4. 2D edge plasma modeling extended up to the main chamber

    Energy Technology Data Exchange (ETDEWEB)

    Dekeyser, W., E-mail: wouter.dekeyser@mech.kuleuven.be [Department of Mechanical Engineering, Katholieke Universiteit Leuven, Celestijnenlaan 300A, 3001 Leuven (Belgium); Baelmans, M. [Department of Mechanical Engineering, Katholieke Universiteit Leuven, Celestijnenlaan 300A, 3001 Leuven (Belgium); Reiter, D.; Boerner, P.; Kotov, V. [Institut fuer Plasmaphysik, Forschungszentrum Juelich GmbH, EURATOM-Association, Trilateral Euregio Cluster, D-52425 Juelich (Germany)

    2011-08-01

    Far SOL plasma flow, and hence main chamber recycling and plasma surface interaction, are today still only very poorly described by current 2D fluid edge codes, such as B2, UEDGE or EDGE2D, due to a common technical limitation. We have extended the B2 plasma fluid solver in the current ITER version of B2-EIRENE (SOLPS4.3) to allow plasma solutions to be obtained up to the 'real vessel wall', at least on the basis of ad hoc far SOL transport models. We apply here the kinetic Monte Carlo Code EIRENE on such plasma solutions to study effects of this model refinement on main chamber fluxes and sputtering, for an ITER configuration. We show that main chamber sputtering may be significantly modified both due to thermalization of CX neutrals in the far SOL and poloidally highly asymmetric plasma wall contact, as compared to hitherto applied teleportation of particle fluxes across this domain.

  5. Effectiveness of Ninth-Grade Physics in Maine: Conceptual Understanding

    OpenAIRE

    O'Brien, Michael; Thompson, John

    2009-01-01

    The Physics First movement - teaching a true physics course to ninth grade students - is gaining popularity in high schools. There are several different rhetorical arguments for and against this movement, and it is quite controversial in physics education. However, there is no actual evidence to assess the success, or failure, of this substantial shift in the science teaching sequence. We have undertaken a comparison study of physics classes taught in ninth- and 12th grade classes in Maine. C...

  6. A Study on Logistics Cluster Competitiveness among Asia Main Countries using the Porter's Diamond Model

    OpenAIRE

    Tae Won Chung

    2016-01-01

    Measurement and discussions of logistics cluster competitiveness with a national approach are required to boost agglomeration effects and potentially create logistics efficiency and productivity. This study developed assessment criteria of logistics cluster competitiveness based on Porter's diamond model, calculated the weight of each criterion by the AHP method, and finally evaluated and discussed logistics cluster competitiveness among Asia main countries. The results indicate that there wa...

  7. Effect of weatherization on radon levels in Maine dwellings

    International Nuclear Information System (INIS)

    Hess, C.T.; Hill, R.C.

    1984-01-01

    A study of radon concentration in the air of 30 Maine dwellings was performed before and after weatherization during November 1982-May 1983. The average radon (.75 pCi/1) was lower than a group of houses in a previous study in October 1980-May 1981 (3.1 pCi/1). The after-weatherization levels show an increase over the before-weatherization levels. Trailers were found to have lower radon concentrations than houses. The maximum value measured was 3.2 pCi/1 before and 6.2 pCi/1 after correction for season of exposure. 13 references, 5 figures, 3 tables

  8. Reduction of Marine Magnetic Data for Modeling the Main Field of the Earth

    Science.gov (United States)

    Baldwin, R. T.; Ridgway, J. R.; Davis, W. M.

    1992-01-01

    The marine data set archived at the National Geophysical Data Center (NGDC) consists of shipborne surveys conducted by various institutes worldwide. This data set spans four decades (1953, 1958, 1960-1987), and contains almost 13 million total intensity observations. These are often less than 1 km apart. These typically measure seafloor spreading anomalies with amplitudes of several hundred nanotesla (nT) which, since they originate in the crust, interfere with main field modeling. The source for these short wavelength features are confined within the magnetic crust (i.e., sources above the Curie isotherm). The main field, on the other hand, is of much longer wavelengths and originates within the earth's core. It is desirable to extract the long wavelength information from the marine data set for use in modeling the main field. This can be accomplished by averaging the data along the track. In addition, those data which are measured during periods of magnetic disturbance can be identified and eliminated. Thus, it should be possible to create a data set which has worldwide data distribution, spans several decades, is not contaminated with short wavelengths of the crustal field or with magnetic storm noise, and which is limited enough in size to be manageable for the main field modeling. The along track filtering described above has proved to be an effective means of condensing large numbers of shipborne magnetic data into a manageable and meaningful data set for main field modeling. Its simplicity and ability to adequately handle varying spatial and sampling constraints has outweighed consideration of more sophisticated approaches. This filtering technique also provides the benefits of smoothing out short wavelength crustal anomalies, discarding data recorded during magnetically noisy periods, and assigning reasonable error estimates to be used in the least square modeling. A useful data set now exists which spans 1953-1987.

  9. Progress on electron cloud effects calculations for the FNAL main injector

    International Nuclear Information System (INIS)

    Furman, Miguel A; Sonnad, Kiran G.; Furman, Miguel A.; Vay, Jean-Luc

    2008-01-01

    We have studied the response of the beam to an electron cloud for the Fermilab Main Injector using the Quasistatic Model [1] implemented into the particle-in-cell code Warp [2]. Specifically, we have addressed the effects due to varying the beam intensity, electron cloud density and chromaticity. In addition, we have estimated the contribution to emittance evolution due to beam space-charge effects. We have carried out a comparison between how the beam responds at injection energy and at top energy. We also present some results on the validation of the computational model, and report on progress towards improving the computational model

  10. Additive Main Effects and Multiplicative Interaction Analysis of ...

    African Journals Online (AJOL)

    This work deals with modeling and examining the GxE interaction pattern of the multi-environment trials of 43 genotypes and eight environments from Southern Ethiopia coffee (Coffea Arabica L.) collections using a randomized complete block design (RCBD) with four replications. The work further attempts to predict yield ...

  11. Verification of RBMK-1500 reactor main circulation circuit model with Cathare V1.3L

    International Nuclear Information System (INIS)

    Jasiulevicius, A.

    2001-01-01

    Among other computer codes, French code CATHARE is also applied for RBMK reactor calculations. In this paper results of such application for Ignalina NPP reactor (RBMK-1500 type) main circulation circuit are presented. Three transients calculations were performed: all main circulation pumps (MCP) trip, trip of one main circulation pump and trip of one main circulation pump without a closure of check valve on the pump line. Calculation results were compared to data from the Ignalina NPP, where all these transients were recorded in the years 1986, 1996 and 1998. The presented studies prove the capability of the CATHARE code to treat thermal-hydraulic transients with a reactor scram in the RBMK, in case of single or multiple pump trips. However, the presented model needs further improvements in order to simulate loss of coolant accidents. For this reason, emergency core cooling system should be included in the model. Additional model improvement is also needed in order to gain more independent pressure behavior in both loops. Also, flow rates through the reactor channels should be modeled by dividing channels into several groups, referring to channel power (in RBMK power produced in a channel, located in different parts of the core is not the same). The point-neutron kinetic model of the CATHARE code is not suitable to predict transients when the reactor is operating at a nominal power level. Such transients would require the use of 3D-neutron kinetics model to describe properly the strong space-time effect on the power distribution in the reactor core

  12. Main control computer security model of closed network systems protection against cyber attacks

    Science.gov (United States)

    Seymen, Bilal

    2014-06-01

    The model that brings the data input/output under control in closed network systems, that maintains the system securely, and that controls the flow of information through the Main Control Computer which also brings the network traffic under control against cyber-attacks. The network, which can be controlled single-handedly thanks to the system designed to enable the network users to make data entry into the system or to extract data from the system securely, intends to minimize the security gaps. Moreover, data input/output record can be kept by means of the user account assigned for each user, and it is also possible to carry out retroactive tracking, if requested. Because the measures that need to be taken for each computer on the network regarding cyber security, do require high cost; it has been intended to provide a cost-effective working environment with this model, only if the Main Control Computer has the updated hardware.

  13. Space-charge effects in the Fermilab Main Ring at 8 GeV

    International Nuclear Information System (INIS)

    Mane, S.R.

    1989-03-01

    I use computer tracking to investigate the effects of space-charge on particle motion in the Fermilab Main Ring at p = 8 GeV/c. The results are found to agree with the Laslett tuneshift formula. Simple model cases are also studied to speed up the tracking. The effects of synchrotron oscillations, via tune modulation and dispersion, are included. 2 refs., 5 figs

  14. Effects of main-sequence mass loss on stellar and galactic chemical evolution

    International Nuclear Information System (INIS)

    Guzik, J.A.

    1988-01-01

    L.A. Willson, G.H. Bowen and C. Struck-Marcell have proposed that 1 to 3 solar mass stars may experience evolutionarily significant mass loss during the early part of their main-sequence phase. The suggested mass-loss mechanism is pulsation, facilitated by rapid rotation. Initial mass-loss rates may be as large as several times 10 -9 M mass of sun/yr, diminishing over several times 10 8 years. The author attempts to test this hypothesis by comparing some theoretical implications with observations. Three areas are addressed: Solar models, cluster HR diagrams, and galactic chemical evolution. Mass-losing solar models were evolved that match the Sun's luminosity and radius at its present age. The most extreme viable models have initial mass 2.0 M 0 , and mass-loss rates decreasing exponentially over 2-3 x 10 8 years. Evolution calculations incorporating main-sequence mass loss were completed for a grid of models with initial masses 1.25 to 2.0 M mass of sun and mass loss timescales 0.2 to 2.0 Gry. Cluster HR diagrams synthesized with these models confirm the potential for the hypothesis to explain observed spreads or bifurcations in the upper main sequence, blue stragglers, anomalous giants, and poor fits of main-sequence turnoffs by standard isochrones. Simple closed galactic chemical evolution models were used to test the effects of main-sequence mass loss on the F and G dwarf distribution. Stars between 3.0 M mass of sun and a metallicity-dependent lower mass are assumed to lose mass. The models produce a 30 to 60% increase in the stars to stars-plus-remnants ratio, with fewer early-F dwarfs and many more late-F dwarfs remaining on the main sequence to the present

  15. An algal model for predicting attainment of tiered biological criteria of Maine's streams and rivers

    Science.gov (United States)

    Danielson, Thomas J.; Loftin, Cyndy; Tsomides, Leonidas; DiFranco, Jeanne L.; Connors, Beth; Courtemanch, David L.; Drummond, Francis; Davies, Susan

    2012-01-01

    State water-quality professionals developing new biological assessment methods often have difficulty relating assessment results to narrative criteria in water-quality standards. An alternative to selecting index thresholds arbitrarily is to include the Biological Condition Gradient (BCG) in the development of the assessment method. The BCG describes tiers of biological community condition to help identify and communicate the position of a water body along a gradient of water quality ranging from natural to degraded. Although originally developed for fish and macroinvertebrate communities of streams and rivers, the BCG is easily adapted to other habitats and taxonomic groups. We developed a discriminant analysis model with stream algal data to predict attainment of tiered aquatic-life uses in Maine's water-quality standards. We modified the BCG framework for Maine stream algae, related the BCG tiers to Maine's tiered aquatic-life uses, and identified appropriate algal metrics for describing BCG tiers. Using a modified Delphi method, 5 aquatic biologists independently evaluated algal community metrics for 230 samples from streams and rivers across the state and assigned a BCG tier (1–6) and Maine water quality class (AA/A, B, C, nonattainment of any class) to each sample. We used minimally disturbed reference sites to approximate natural conditions (Tier 1). Biologist class assignments were unanimous for 53% of samples, and 42% of samples differed by 1 class. The biologists debated and developed consensus class assignments. A linear discriminant model built to replicate a priori class assignments correctly classified 95% of 150 samples in the model training set and 91% of 80 samples in the model validation set. Locally derived metrics based on BCG taxon tolerance groupings (e.g., sensitive, intermediate, tolerant) were more effective than were metrics developed in other regions. Adding the algal discriminant model to Maine's existing macroinvertebrate discriminant

  16. Effects of mass loss on the evolution of massive stars. I. Main-sequence evolution

    International Nuclear Information System (INIS)

    Dearborn, D.S.P.; Blake, J.B.; Hainebach, K.L.; Schramm, D.N.

    1978-01-01

    The effect of mass loss on the evolution and surface composition of massive stars during main-sequence evolution are examined. While some details of the evolutionary track depend on the formula used for the mass loss, the results appear most sensitive to the total mass removed during the main-sequence lifetime. It was found that low mass-loss rates have very little effect on the evolution of a star; the track is slightly subluminous, but the lifetime is almost unaffected. High rates of mass loss lead to a hot, high-luminosity stellar model with a helium core surrounded by a hydrogen-deficient (Xapprox.0.1) envelope. The main-sequence lifetime is extended by a factor of 2--3. These models may be identified with Wolf-Rayet stars. Between these mass-loss extremes are intermediate models which appear as OBN stars on the main sequence. The mass-loss rates required for significant observable effects range from 8 x 10 -7 to 10 -5 M/sub sun/ yr -1 , depending on the initial stellar mass. It is found that observationally consistent mass-loss rates for stars with M> or =30 M/sub sun/ may be sufficiently high that these stars lose mass on a time scale more rapidly than their main-sequence core evolution time. This result implies that the helium cores resulting from the main-sequence evolution of these massive stars may all be very similar to that of a star of Mapprox.30 M/sub sun/ regardless of the zero-age mass

  17. Predictive Modeling of Spinner Dolphin (Stenella longirostris) Resting Habitat in the Main Hawaiian Islands

    Science.gov (United States)

    Thorne, Lesley H.; Johnston, David W.; Urban, Dean L.; Tyne, Julian; Bejder, Lars; Baird, Robin W.; Yin, Suzanne; Rickards, Susan H.; Deakos, Mark H.; Mobley, Joseph R.; Pack, Adam A.; Chapla Hill, Marie

    2012-01-01

    Predictive habitat models can provide critical information that is necessary in many conservation applications. Using Maximum Entropy modeling, we characterized habitat relationships and generated spatial predictions of spinner dolphin (Stenella longirostris) resting habitat in the main Hawaiian Islands. Spinner dolphins in Hawai'i exhibit predictable daily movements, using inshore bays as resting habitat during daylight hours and foraging in offshore waters at night. There are growing concerns regarding the effects of human activities on spinner dolphins resting in coastal areas. However, the environmental factors that define suitable resting habitat remain unclear and must be assessed and quantified in order to properly address interactions between humans and spinner dolphins. We used a series of dolphin sightings from recent surveys in the main Hawaiian Islands and a suite of environmental variables hypothesized as being important to resting habitat to model spinner dolphin resting habitat. The model performed well in predicting resting habitat and indicated that proximity to deep water foraging areas, depth, the proportion of bays with shallow depths, and rugosity were important predictors of spinner dolphin habitat. Predicted locations of suitable spinner dolphin resting habitat provided in this study indicate areas where future survey efforts should be focused and highlight potential areas of conflict with human activities. This study provides an example of a presence-only habitat model used to inform the management of a species for which patterns of habitat availability are poorly understood. PMID:22937022

  18. Simulation of streamflow in the Pleasant, Narraguagus, Sheepscot, and Royal Rivers, Maine, using watershed models

    Science.gov (United States)

    Dudley, Robert W.; Nielsen, Martha G.

    2011-01-01

    The U.S. Geological Survey (USGS) began a study in 2008 to investigate anticipated changes in summer streamflows and stream temperatures in four coastal Maine river basins and the potential effects of those changes on populations of endangered Atlantic salmon. To achieve this purpose, it was necessary to characterize the quantity and timing of streamflow in these rivers by developing and evaluating a distributed-parameter watershed model for a part of each river basin by using the USGS Precipitation-Runoff Modeling System (PRMS). The GIS (geographic information system) Weasel, a USGS software application, was used to delineate the four study basins and their many subbasins, and to derive parameters for their geographic features. The models were calibrated using a four-step optimization procedure in which model output was evaluated against four datasets for calibrating solar radiation, potential evapotranspiration, annual and seasonal water balances, and daily streamflows. The calibration procedure involved thousands of model runs that used the USGS software application Luca (Let us calibrate). Luca uses the Shuffled Complex Evolution (SCE) global search algorithm to calibrate the model parameters. The calibrated watershed models performed satisfactorily, in that Nash-Sutcliffe efficiency (NSE) statistic values for the calibration periods ranged from 0.59 to 0.75 (on a scale of negative infinity to 1) and NSE statistic values for the evaluation periods ranged from 0.55 to 0.73. The calibrated watershed models simulate daily streamflow at many locations in each study basin. These models enable natural resources managers to characterize the timing and amount of streamflow in order to support a variety of water-resources efforts including water-quality calculations, assessments of water use, modeling of population dynamics and migration of Atlantic salmon, modeling and assessment of habitat, and simulation of anticipated changes to streamflow and water temperature

  19. Effects of Main-Sequence Mass Loss on Stellar and Galactic Chemical Evolution.

    Science.gov (United States)

    Guzik, Joyce Ann

    1988-06-01

    L. A. Willson, G. H. Bowen and C. Struck -Marcell have proposed that 1 to 3 solar mass stars may experience evolutionarily significant mass loss during the early part of their main-sequence phase. The suggested mass-loss mechanism is pulsation, facilitated by rapid rotation. Initial mass-loss rates may be as large as several times 10^{-9}M o/yr, diminishing over several times 10^8 years. We attempted to test this hypothesis by comparing some theoretical implications with observations. Three areas are addressed: Solar models, cluster HR diagrams, and galactic chemical evolution. Mass-losing solar models were evolved that match the Sun's luminosity and radius at its present age. The most extreme viable models have initial mass 2.0 M o, and mass-loss rates decreasing exponentially over 2-3 times 10^8 years. Compared to a constant -mass model, these models require a reduced initial ^4He abundance, have deeper envelope convection zones and higher ^8B neutrino fluxes. Early processing of present surface layers at higher interior temperatures increases the surface ^3He abundance, destroys Li, Be and B, and decreases the surface C/N ratio following first dredge-up. Evolution calculations incorporating main-sequence mass loss were completed for a grid of models with initial masses 1.25 to 2.0 Mo and mass loss timescales 0.2 to 2.0 Gyr. Cluster HR diagrams synthesized with these models confirm the potential for the hypothesis to explain observed spreads or bifurcations in the upper main sequence, blue stragglers, anomalous giants, and poor fits of main-sequence turnoffs by standard isochrones. Simple closed galactic chemical evolution models were used to test the effects of main-sequence mass loss on the F and G dwarf distribution. Stars between 3.0 M o and a metallicity -dependent lower mass are assumed to lose mass. The models produce a 30 to 60% increase in the stars to stars-plus -remnants ratio, with fewer early-F dwarfs and many more late-F dwarfs remaining on the main

  20. Cost-Effectiveness Analysis of the Residential Provisions of the 2015 IECC for Maine

    Energy Technology Data Exchange (ETDEWEB)

    Mendon, Vrushali V. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Zhao, Mingjie [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Taylor, Zachary T. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Poehlman, Eric A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2016-02-15

    The 2015 IECC provides cost-effective savings for residential buildings in Maine. Moving to the 2015 IECC from the 2009 IECC base code is cost-effective for residential buildings in all climate zones in Maine.

  1. Sensitivity Analysis on Fire Modeling of Main Control Board Fire Using Fire Dynamics Simulator

    International Nuclear Information System (INIS)

    Kang, Dae Il; Lim, Ho Gon

    2015-01-01

    In this study, sensitivity analyses for an MCB fire were performed to identify the effects on the MCR forced abandonment time according to the changes of height and number for fire initiation places. Hanul Unit 3 NPP was selected as a reference plant for this study. In this study, sensitivity analyses for an MCB fire were performed to identify the effects on the MCR forced abandonment time according to the changes of height and number of fire initiation places. A main control board (MCB) fire can cause a forced main control room (MCR) abandonment of the operators as well as the function failures or spurious operations of the control and instrumentation-related components. If the MCR cannot be habitable, a safe shutdown from outside the MCR can be achieved and maintained at an alternate shutdown panel independent from the MCR. When the fire modeling for an electrical cabinet such as an MCB was performed, its many input parameters can affect the fire simulation results. This study results showed that the decrease in the height of fire ignition place and the use of single fire ignition place in fire modeling for the propagating fire shortened MCR abandonment time

  2. Sensitivity Analysis on Fire Modeling of Main Control Board Fire Using Fire Dynamics Simulator

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Dae Il; Lim, Ho Gon [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2015-10-15

    In this study, sensitivity analyses for an MCB fire were performed to identify the effects on the MCR forced abandonment time according to the changes of height and number for fire initiation places. Hanul Unit 3 NPP was selected as a reference plant for this study. In this study, sensitivity analyses for an MCB fire were performed to identify the effects on the MCR forced abandonment time according to the changes of height and number of fire initiation places. A main control board (MCB) fire can cause a forced main control room (MCR) abandonment of the operators as well as the function failures or spurious operations of the control and instrumentation-related components. If the MCR cannot be habitable, a safe shutdown from outside the MCR can be achieved and maintained at an alternate shutdown panel independent from the MCR. When the fire modeling for an electrical cabinet such as an MCB was performed, its many input parameters can affect the fire simulation results. This study results showed that the decrease in the height of fire ignition place and the use of single fire ignition place in fire modeling for the propagating fire shortened MCR abandonment time.

  3. Modeling of the Voltage Waves in the LHC Main Dipole Circuits

    CERN Document Server

    Ravaioli, E; Formenti, F; Steckert, J; Thiesen, H; Verweij, A

    2012-01-01

    When a fast power abort is triggered in the LHC main dipole chain, voltage transients are generated at the output of the power converter and across the energy-extraction switches. The voltage waves propagate through the chain of 154 superconducting dipoles and can have undesired effects leading to spurious triggering of the quench protection system and firing of the quench heaters. The phase velocity of the waves travelling along the chain changes due to the inhomogeneous AC behavior of the dipoles. Furthermore, complex phenomena of reflection and superposition are present in the circuit. For these reasons analytical calculations are not sufficient for properly analyzing the circuit behavior after a fast power abort. The transients following the switch-off of the power converter and the opening of the switches are analyzed by means of a complete electrical model, developed with the Cadence© suite (PSpice© based). The model comprises all the electrical components of the circuit, additional components simula...

  4. A Study on Logistics Cluster Competitiveness among Asia Main Countries using the Porter's Diamond Model

    Directory of Open Access Journals (Sweden)

    Tae Won Chung

    2016-12-01

    Full Text Available Measurement and discussions of logistics cluster competitiveness with a national approach are required to boost agglomeration effects and potentially create logistics efficiency and productivity. This study developed assessment criteria of logistics cluster competitiveness based on Porter's diamond model, calculated the weight of each criterion by the AHP method, and finally evaluated and discussed logistics cluster competitiveness among Asia main countries. The results indicate that there was a large difference in logistics cluster competitiveness among six countries. The logistics cluster competitiveness scores of Singapore (7.93, Japan (7.38, and Hong Kong (7.04 are observably different from those of China (5.40, Korea (5.08, and Malaysia (3.46. Singapore, with the highest competitiveness score, revealed its absolute advantage in logistics cluster indices. These research results intend to provide logistics policy makers with some strategic recommendations, and may serve as a baseline for further logistics cluster studies using Porter's diamond model.

  5. Tunnelling effect enhanced by lattice screening as main cold fusion mechanism: An brief theoretical overview

    International Nuclear Information System (INIS)

    Frisone, F.

    2007-01-01

    In this paper are illustrated the main features of tunneling traveling between two deuterons within a lattice. Considering the screening effect due lattice electrons we compare the d-d fusion rate evaluated from different authors assuming different screening efficiency and different d-d potentials. Then, we propose a effective potential which describe very well the attractive contribute due to plasmon exchange between two deuterons and by means of it we will compute the d-d fusion rates for different energy values. Finally the good agreement between theoretical and experimental results proves the reality of cold fusion phenomena and the reliability of our model

  6. Weather Research and Forecasting (WRF) Regional Atmospheric Model: Main Hawaiian Islands

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Weather Research and Forecasting (WRF) mesoscale numerical weather prediction model 7-day hourly forecast for the region surrounding the Main Hawaiian Islands (MHI)...

  7. Research on cognitive reliability model for main control room considering human factors in nuclear power plants

    International Nuclear Information System (INIS)

    Jiang Jianjun; Zhang Li; Wang Yiqun; Zhang Kun; Peng Yuyuan; Zhou Cheng

    2012-01-01

    Facing the shortcomings of the traditional cognitive factors and cognitive model, this paper presents a Bayesian networks cognitive reliability model by taking the main control room as a reference background and human factors as the key points. The model mainly analyzes the cognitive reliability affected by the human factors, and for the cognitive node and influence factors corresponding to cognitive node, a series of methods and function formulas to compute the node cognitive reliability is proposed. The model and corresponding methods can be applied to the evaluation of cognitive process for the nuclear power plant operators and have a certain significance for the prevention of safety accidents in nuclear power plants. (authors)

  8. LARGE SCALE DISTRIBUTED PARAMETER MODEL OF MAIN MAGNET SYSTEM AND FREQUENCY DECOMPOSITION ANALYSIS

    Energy Technology Data Exchange (ETDEWEB)

    ZHANG,W.; MARNERIS, I.; SANDBERG, J.

    2007-06-25

    Large accelerator main magnet system consists of hundreds, even thousands, of dipole magnets. They are linked together under selected configurations to provide highly uniform dipole fields when powered. Distributed capacitance, insulation resistance, coil resistance, magnet inductance, and coupling inductance of upper and lower pancakes make each magnet a complex network. When all dipole magnets are chained together in a circle, they become a coupled pair of very high order complex ladder networks. In this study, a network of more than thousand inductive, capacitive or resistive elements are used to model an actual system. The circuit is a large-scale network. Its equivalent polynomial form has several hundred degrees. Analysis of this high order circuit and simulation of the response of any or all components is often computationally infeasible. We present methods to use frequency decomposition approach to effectively simulate and analyze magnet configuration and power supply topologies.

  9. Simulations of Electron Cloud Effects on the Beam Dynamics for the FNAL Main Injector Upgrade

    International Nuclear Information System (INIS)

    Sonnad Kiran G.; Furman, Miguel; Vay, Jean-Luc; Venturini, Marco; Celata, Christine M.; Grote, David

    2006-01-01

    The Fermilab main injector (MI) is being considered for an upgrade as part of the high intensity neutrino source (HINS) effort. This upgrade will involve a significant increasing of the bunch intensity relative to its present value. Such an increase will place the MI in a regime in which electron-cloud effects are expected to become important. We have used the electrostatic particle-in-cell code WARP, recently augmented with new modeling capabilities and simulation techniques, to study the dynamics of beam-electron cloud interaction. This work in progress involves a systematic assessment of beam instabilities due to the presence of electron clouds

  10. Simplified Models for Analysis and Design of the Control System Main Loops of CAREM Reactor

    International Nuclear Information System (INIS)

    Etchepareborda, Andres; Flury, Celso

    2000-01-01

    The target of this work is to show a few models developed for control analysis and design of the reactor CAREM's main control loops within a broad range of power (between 40 % and 100%).By one side, it is shown the main features of a analytic model programed in MATLAB.This model is based on fitting steady state points at different power levels of the CAREM's RETRAN model.By the other side, it is shown linear models of black-box type denoting the perturbed behavior of the system for each level power point.These models are identified from temporal responses of CAREM's RETRAN model to perturbed input signals over the different steady power level points.Then the dynamics of these models are verified contrasting the temporal responses of the RETRAN model versus the responses of the MATLAB model and the identified models, in each steady power level point.Also are contrasting the frequency response of the linearization of MATLAB model versus the frequency response of the identified models, in each steady power level point.Either the MATLAB model as the identified models are good enough for the control analysis and design of the three main control loops.The MATLAB model has a few differences against the RETRAN model in the primary pressure output variable, that it must be taken into account in the design of this control loop if this model is used.The aim of these models is to represent in a satisfactory way the dynamics of the plant for a later control analysis and design of the control loops in a frequency range between 0.01 rad/seg and 0.3 rad/seg, and a power range between 40 % and 100 %

  11. Issues regarding Risk Effect Analysis of Digitalized Safety Systems and Main Risk Contributors

    International Nuclear Information System (INIS)

    Kang, Hyun Gook; Jang, Seung-Cheol

    2008-01-01

    Risk factors of safety-critical digital systems affect overall plant risk. In order to assess this risk effect, a risk model of a digitalized safety system is required. This article aims to provide an overview of the issues when developing a risk model and demonstrate their effect on plant risk quantitatively. Research activities in Korea for addressing these various issues, such as the software failure probability and the fault coverage of self monitoring mechanism are also described. The main risk contributors related to the digitalized safety system were determined in a quantitative manner. Reactor protection system and engineered safety feature component control system designed as part of the Korean Nuclear I and C System project are used as example systems. Fault-tree models were developed to assess the failure probability of a system function which is designed to generate an automated signal for actuating both of the reactor trip and the complicated accident-mitigation actions. The developed fault trees were combined with a plant risk model to evaluate the effect of a digitalized system's failure on the plant risk. (authors)

  12. A six-part collisional model of the main asteroid belt

    Science.gov (United States)

    Cibulková, H.; Brož, M.; Benavidez, P. G.

    2014-10-01

    In this work, we construct a new model for the collisional evolution of the main asteroid belt. Our goals are to test the scaling law of Benz and Asphaug (Benz, W., Asphaug, E. [1999]. Icarus, 142, 5-20) and ascertain if it can be used for the whole belt. We want to find initial size-frequency distributions (SFDs) for the considered six parts of the belt (inner, middle, “pristine”, outer, Cybele zone, high-inclination region) and to verify if the number of synthetic asteroid families created during the simulation matches the number of observed families as well. We used new observational data from the WISE satellite (Masiero et al., 2011) to construct the observed SFDs. We simulate mutual collisions of asteroids with a modified version of the Boulder code (Morbidelli, A., et al. [2009]. Icarus, 204, 558-573), where the results of hydrodynamic (SPH) simulations of Durda et al. (Durda, D.D., et al. [2007]. Icarus, 498-516) and Benavidez et al. (Benavidez, P.G., et al. [2012]. 219, 57-76) are included. Because material characteristics can significantly affect breakups, we created two models - for monolithic asteroids and for rubble-piles. To explain the observed SFDs in the size range D=1 to 10 km we have to also account for dynamical depletion due to the Yarkovsky effect. The assumption of (purely) rubble-pile asteroids leads to a significantly worse fit to the observed data, so that we can conclude that majority of main-belt asteroids are rather monolithic. Our work may also serve as a motivation for further SPH simulations of disruptions of smaller targets (with a parent body size of the order of 1 km).

  13. Variational Data Assimilative Modeling of the Gulf of Maine Circulation in Spring and Summer 2010

    OpenAIRE

    Li, Yizhen; He, Ruoying; Chen, Ke; McGillicuddy, Dennis J.

    2015-01-01

    A data assimilative ocean circulation model is used to hindcast the Gulf of Maine (GOM) circulation in spring and summer 2010. Using the recently developed incremental strong constraint 4D Variational data assimilation algorithm, the model assimilates satellite sea surface temperature and in situ temperature and salinity profiles measured by expendable bathythermograph, Argo floats, and shipboard CTD casts. Validation against independent observations shows that the model skill is significantl...

  14. Empirical tests of pre-main-sequence stellar evolution models with eclipsing binaries

    Science.gov (United States)

    Stassun, Keivan G.; Feiden, Gregory A.; Torres, Guillermo

    2014-06-01

    We examine the performance of standard pre-main-sequence (PMS) stellar evolution models against the accurately measured properties of a benchmark sample of 26 PMS stars in 13 eclipsing binary (EB) systems having masses 0.04-4.0 M⊙ and nominal ages ≈1-20 Myr. We provide a definitive compilation of all fundamental properties for the EBs, with a careful and consistent reassessment of observational uncertainties. We also provide a definitive compilation of the various PMS model sets, including physical ingredients and limits of applicability. No set of model isochrones is able to successfully reproduce all of the measured properties of all of the EBs. In the H-R diagram, the masses inferred for the individual stars by the models are accurate to better than 10% at ≳1 M⊙, but below 1 M⊙ they are discrepant by 50-100%. Adjusting the observed radii and temperatures using empirical relations for the effects of magnetic activity helps to resolve the discrepancies in a few cases, but fails as a general solution. We find evidence that the failure of the models to match the data is linked to the triples in the EB sample; at least half of the EBs possess tertiary companions. Excluding the triples, the models reproduce the stellar masses to better than ∼10% in the H-R diagram, down to 0.5 M⊙, below which the current sample is fully contaminated by tertiaries. We consider several mechanisms by which a tertiary might cause changes in the EB properties and thus corrupt the agreement with stellar model predictions. We show that the energies of the tertiary orbits are comparable to that needed to potentially explain the scatter in the EB properties through injection of heat, perhaps involving tidal interaction. It seems from the evidence at hand that this mechanism, however it operates in detail, has more influence on the surface properties of the stars than on their internal structure, as the lithium abundances are broadly in good agreement with model predictions. The

  15. COMPETENCE-BASED APPROACH TO MODELLING STRUCTURES OF THE MAIN EDUCATIONAL PROGRAM

    Directory of Open Access Journals (Sweden)

    V. A. Gerasimova

    2015-01-01

    Full Text Available By the analysis results of scientific works in the field of competence-based approach in education authors proved need of computer support of the planning and development stage of the main educational program, they developed the main educational program structure automatic formation model on the graphs basis, offered the integrated criterion of an discipline assessment and developed a strategic map of a discipline complex assessment. The executed theoretical researches are a basis for creation of the main educational program planning and development support automated system.

  16. A new 6-part collisional model of the Main Asteroid Belt

    Science.gov (United States)

    Broz, Miroslav; Cibulkova, H.

    2013-10-01

    In this work, we constructed a new model for the collisional evolution of the Main Asteroid Belt. Our goals are to test the scaling law from the work of Benz & Asphaug (1999) and ascertain if it can be used for the whole belt. We want to find initial size-frequency distributions (SFDs) for the considered six parts of the belt, and to verify if the number of asteroid families created during the simulation matches the number of observed families as well. We used new observational data from the WISE satellite (Masiero et al., 2011) to construct the observed SFDs. We simulated mutual collisions of asteroids with a modified Boulder code (Morbidelli et al., 2009), in which the results of hydrodynamic (SPH) simulations from the work of Durda et al. (2007) are included. Because material characteristics can affect breakups, we created two models - for monolithic asteroids and for rubble-piles (Benavidez et al., 2012). To explain the observed SFDs in the size range D = 1 to 10 km we have to also account for dynamical depletion due to the Yarkovsky effect. Our work may also serve as a motivation for further SPH simulations of disruptions of smaller targets (parent body size of the order of 1 km). The work of MB was supported by grant GACR 13-013085 of the Czech Science Foundation and the Research Programme MSM0021620860 of the Czech Ministry of Education.

  17. THE QUADRUPLE PRE-MAIN-SEQUENCE SYSTEM LkCa 3: IMPLICATIONS FOR STELLAR EVOLUTION MODELS

    International Nuclear Information System (INIS)

    Torres, Guillermo; Latham, David W.; Ruíz-Rodríguez, Dary; Prato, L.; Wasserman, Lawrence H.; Badenas, Mariona; Schaefer, G. H.; Mathieu, Robert D.

    2013-01-01

    We report the discovery that the pre-main-sequence (PMS) object LkCa 3 in the Taurus-Auriga star-forming region is a hierarchical quadruple system of M stars. It was previously known to be a close (∼0.''5) visual pair, with one component being a moderately eccentric 12.94 day single-lined spectroscopic binary. A re-analysis of archival optical spectra complemented by new near-infrared (NIR) spectroscopy shows both visual components to be double lined; the second one has a period of 4.06 days and a circular orbit. In addition to the orbital elements, we determine optical and NIR flux ratios, effective temperatures, and projected rotational velocities for all four stars. Using existing photometric monitoring observations of the system that had previously revealed the rotational period of the primary in the longer-period binary, we also detect the rotational signal of the primary in the 4.06 day binary, which is synchronized with the orbital motion. With only the assumption of coevality, a comparison of all of these constraints with current stellar evolution models from the Dartmouth series points to an age of 1.4 Myr and a distance of 133 pc, consistent with previous estimates for the region and suggesting that the system is on the near side of the Taurus complex. Similar comparisons of the properties of LkCa 3 and the well-known quadruple PMS system GG Tau with the widely used models from the Lyon series for a mixing length parameter of α ML = 1.0 strongly favor the Dartmouth models

  18. Main geologic characteristics and metallogenic models of uranium deposits in Zhejiang

    International Nuclear Information System (INIS)

    Tang Qitao

    2000-01-01

    Uranium resources in Zhejiang is abundant with numerous mineralization types. According to the genesis they can be classified into: sedimentary-reworking type, hydrothermal type and infiltration type. The author briefly describes main geologic characteristics and metallogenic models of different type uranium deposits

  19. The spinning Astrid-2 satellite used for modeling the Earth's main magnetic field

    DEFF Research Database (Denmark)

    Merayo, José M.G.; Jørgensen, P.S.; Risbo, T.

    2002-01-01

    orientation of the magnetometer could then be determined simultaneously with the instrument intrinsic calibration and the estimate of main field model coefficients. Hence, apart from the scientific use of the magnetic data, the attitude of the spacecraft may be estimated with high precision....

  20. Fractional-order mathematical model of an irrigation main canal pool

    Directory of Open Access Journals (Sweden)

    Shlomi N. Calderon-Valdez

    2015-09-01

    Full Text Available In this paper a fractional order model for an irrigation main canal is proposed. It is based on the experiments developed in a laboratory prototype of a hydraulic canal and the application of a direct system identification methodology. The hydraulic processes that take place in this canal are equivalent to those that occur in real main irrigation canals and the results obtained here can therefore be easily extended to real canals. The accuracy of the proposed fractional order model is compared by deriving two other integer-order models of the canal of a complexity similar to that proposed here. The parameters of these three mathematical models have been identified by minimizing the Integral Square Error (ISE performance index existing between the models and the real-time experimental data obtained from the canal prototype. A comparison of the performances of these three models shows that the fractional-order model has the lowest error and therefore the higher accuracy. Experiments showed that our model outperformed the accuracy of the integer-order models by about 25%, which is a significant improvement as regards to capturing the canal dynamics.

  1. Modeling radiation loads in the ILC main linac and a novel approach to treat dark current

    Energy Technology Data Exchange (ETDEWEB)

    Mokhov, Nilolai V. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Rakhno, Igor L. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Tropin, Igor S. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States)

    2017-09-11

    Electromagnetic and hadron showers generated by electrons of dark current (DC) can represent a significant radiation threat to the ILC linac equipment and personnel. In this study, a commissioning scenario is analysed which is considered as the worst-case scenario for the main linac regarding the DC contribution to the radiation environment in the tunnel. A normal operation scenario is analysed as well. An emphasis is made on radiation load to sensitive electronic equipment—cryogenic thermometers inside the cryomodules. Prompt and residual dose rates in the ILC main linac tunnels were also calculated in these new high-statistics runs. A novel approach was developed—as a part of general purpose Monte Carlo code MARS15—to model generation, acceleration and transport of DC electrons in electromagnetic fields inside SRF cavities. Comparisons were made with a standard approach when a set of pre-calculated DC electron trajectories is used, with a proper normalization, as a source for Monte Carlo modelling. Results of MARS15 Monte Carlo calculations, performed for the current main linac tunnel design, reveal that the peak absorbed dose in the cryogenic thermometers in the main tunnel for 20 years of operation is about 0.8 MGy. The calculated contact residual dose on cryomodules and tunnel walls in the main tunnel for typical irradiation and cooling conditions is 0.1 and 0.01 mSv/hr, respectively.

  2. The effect of main alloying elements on the physical properties of Al–Si foundry alloys

    International Nuclear Information System (INIS)

    Stadler, F.; Antrekowitsch, H.; Fragner, W.; Kaufmann, H.; Pinatel, E.R.; Uggowitzer, P.J.

    2013-01-01

    In this study we describe the effect of the main alloying elements Si, Cu and Ni on the thermal properties of hypoeutectic and near-eutectic Al–Si foundry alloys. By means of systematic variations of the chemical composition, the influence of the amount of ‘second phases’ on the thermal conductivity, thermal expansion coefficient, and thermal shock resistance is evaluated. Thermodynamic calculations predicting the phase formation in multi-component Al–Si cast alloys were carried out and verified using SEM, EDX and XRD analysis. The experimentally obtained data are discussed on a systematic basis of thermodynamic calculations and compared to theoretical models for the thermal conductivity and thermal expansion of heterogeneous solids.

  3. Biological-Physical Coupling in the Gulf of Maine: Satellite and Model Studies of Phytoplankton Variability

    Science.gov (United States)

    Thomas, Andrew C.; Chai, F.; Townsend, D. W.; Xue, H.

    2002-01-01

    The goals of this project were to acquire, process, QC, archive and analyze SeaWiFS chlorophyll fields over the Gulf of Maine and Scotia Shelf region. The focus of the analysis effort was to calculate and quantify seasonality and interannual. variability of SeaWiFS-measured phytoplankton biomass in the study area and compare these to physical forcing and hydrography. An additional focus within this effort was on regional differences within the heterogeneous biophysical regions of the Gulf of Maine / Scotia Shelf. Overall goals were approached through the combined use of SeaWiFS and AVHRR data and the development of a coupled biology-physical numerical model.

  4. Modeling soil organic carbon dynamics and their driving factors in the main global cereal cropping systems

    Science.gov (United States)

    Wang, Guocheng; Zhang, Wen; Sun, Wenjuan; Li, Tingting; Han, Pengfei

    2017-10-01

    Changes in the soil organic carbon (SOC) stock are determined by the balance between the carbon input from organic materials and the output from the decomposition of soil C. The fate of SOC in cropland soils plays a significant role in both sustainable agricultural production and climate change mitigation. The spatiotemporal changes of soil organic carbon in croplands in response to different carbon (C) input management and environmental conditions across the main global cereal systems were studied using a modeling approach. We also identified the key variables that drive SOC changes at a high spatial resolution (0.1° × 0.1°) and over a long timescale (54 years from 1961 to 2014). A widely used soil C turnover model (RothC) and state-of-the-art databases of soil and climate variables were used in the present study. The model simulations suggested that, on a global average, the cropland SOC density increased at annual rates of 0.22, 0.45 and 0.69 Mg C ha-1 yr-1 under crop residue retention rates of 30, 60 and 90 %, respectively. Increasing the quantity of C input could enhance soil C sequestration or reduce the rate of soil C loss, depending largely on the local soil and climate conditions. Spatially, under a specific crop residue retention rate, relatively higher soil C sinks were found across the central parts of the USA, western Europe, and the northern regions of China. Relatively smaller soil C sinks occurred in the high-latitude regions of both the Northern and Southern hemispheres, and SOC decreased across the equatorial zones of Asia, Africa and America. We found that SOC change was significantly influenced by the crop residue retention rate (linearly positive) and the edaphic variable of initial SOC content (linearly negative). Temperature had weak negative effects, and precipitation had significantly negative impacts on SOC changes. The results can help guide carbon input management practices to effectively mitigate climate change through soil C

  5. Modeling soil organic carbon dynamics and their driving factors in the main global cereal cropping systems

    Directory of Open Access Journals (Sweden)

    G. Wang

    2017-10-01

    Full Text Available Changes in the soil organic carbon (SOC stock are determined by the balance between the carbon input from organic materials and the output from the decomposition of soil C. The fate of SOC in cropland soils plays a significant role in both sustainable agricultural production and climate change mitigation. The spatiotemporal changes of soil organic carbon in croplands in response to different carbon (C input management and environmental conditions across the main global cereal systems were studied using a modeling approach. We also identified the key variables that drive SOC changes at a high spatial resolution (0.1°  ×  0.1° and over a long timescale (54 years from 1961 to 2014. A widely used soil C turnover model (RothC and state-of-the-art databases of soil and climate variables were used in the present study. The model simulations suggested that, on a global average, the cropland SOC density increased at annual rates of 0.22, 0.45 and 0.69 Mg C ha−1 yr−1 under crop residue retention rates of 30, 60 and 90 %, respectively. Increasing the quantity of C input could enhance soil C sequestration or reduce the rate of soil C loss, depending largely on the local soil and climate conditions. Spatially, under a specific crop residue retention rate, relatively higher soil C sinks were found across the central parts of the USA, western Europe, and the northern regions of China. Relatively smaller soil C sinks occurred in the high-latitude regions of both the Northern and Southern hemispheres, and SOC decreased across the equatorial zones of Asia, Africa and America. We found that SOC change was significantly influenced by the crop residue retention rate (linearly positive and the edaphic variable of initial SOC content (linearly negative. Temperature had weak negative effects, and precipitation had significantly negative impacts on SOC changes. The results can help guide carbon input management practices to

  6. Main Battle Tank Flexible Gun Tube Disturbance Model: Three-Segment Model

    National Research Council Canada - National Science Library

    Sneck, Henry

    2002-01-01

    ... them. It was found that, contrary to the previously analyzed two degree-of-freedom segment model, the muzzle-end segment could be stabilized by the proper choice of transfer functions and elevation driveline response...

  7. The effective teacher: definition and main aspects in the educational research

    Directory of Open Access Journals (Sweden)

    Eleonora Concina

    2016-07-01

    Full Text Available For fostering a significant learning process, the teacher has a relevant role, as a co-protagonist with the student in the educational process. For this reason, many studies in the educational field have tried to examine the main characteristics of the effective teacher. They have searched for a more general dimension of efficacy, which can summarize effective teacher’s aspects that are common in different disciplines. With the knowledge of disciplinary contents, elements connected to teacher’s personal and professional dimensions have emerged. The aim of the present paper is to consider the main international research contributions on effective teacher and to suggest a summary model, which can offer a representation of the relationships between the different elements.L’insegnante efficace: definizione e caratteristiche nella ricerca educativaLa figura del docente assume un ruolo rilevante nella promozione di un apprendimento significativo, come co-protagonista, insieme con lo studente, del processo educativo. Per questo motivo numerosi studi in ambito educativo hanno cercato di esaminare le caratteristiche dell’insegnante efficace. Si è cercato di delineare una dimensione di efficacia più generale, che riassuma aspetti comuni degli insegnanti considerati efficaci in varie discipline. Accanto alla conoscenza dei contenuti disciplinari, sono emersi elementi legati alla dimensione personale e a quella professionale del docente. L’obiettivo del presente articolo è di considerare i principali contributi internazionali di ricerca relativi alla tematica dell’insegnante efficace e di proporre un modello, che possa fornire indicazioni sulle possibili relazioni tra i diversi elementi.

  8. Research on PCPV for BWR - physical model as design tool - main results

    International Nuclear Information System (INIS)

    Fumagalli, E.; Verdelli, G.

    1975-01-01

    ISMES (Experimental Institute for Models and Structures) is now carrying out a series of tests on physical models as a part of a research programme sponsored by DSR (Studies and Research Direction) of ENEL (Italian State Electricity Board) on behalf of CPN (Nuclear Design and Construction Centre) of ENEL with the aim to experience a 'Thin'-walled PCPV for 'BWR'. The physical model, together with the mathematical model and the rheological model of the materials, is intended as a meaningful design tool. The mathematical model covers the overall structural design phase, (geometries) and the linear behaviour, whereas the physical model, besides of a global information to be compared with the results of the mathematical model, supplies a number of data as the non-linear behaviour up to failure and local conditions (penetration area etc.) are concerned. The aim of the first phase of this research programme is to make a comparison between the calculation and experiment tests as the thicknesses of the wall and the bottom slab are concerned, whereas the second phase of the research deals with the behaviour of the removable lid and its connection with the main structure. To do this, a model in scale 1:10 has been designed which symmetrically reproduces with respect to the equator, the bottom part of the structure. In the bottom slab the penetrations of the prototype design are reproduced, whereas the upper slab is plain. This paper describes the model, and illustrates the main results, underlining the different behaviour of the upper and bottom slabs up to collapse

  9. The Lower Main Sequence of Stars in the Solar Neighborhood: Model Predictions Versus Observation

    Directory of Open Access Journals (Sweden)

    Bartašiūtė S.

    2012-09-01

    Full Text Available We have used the Simbad database and VizieR catalogue access tools to construct the observational color-absolute magnitude diagrams of nearby K-M dwarfs with precise Hipparcos parallaxes (σπ/π ≤ 0:05. Particular attention has been paid to removing unresolved double/multiple stars and variables. In addition to archival data, we have made use of nearly 2000 new radial-velocity measurements of K-M dwarfs to identify spectroscopic binary candidates. The main sequences, cleaned from unresolved binaries, variable stars, and old population stars which can also widen the sequence due to their presumably lower metallicity, were compared to available solar-metallicity models. Significant offsets of most of the model main-sequence lines are seen with respect to observational data, especially for the lower-mass stars. Only the location and slope of the Victoria-Regina and, partly, BaSTI isochrones match the data quite well.

  10. A Non-Linear Finite Element Model for the LHC Main Dipole Coil Cross-Section

    CERN Document Server

    Pojer, M; Scandale, Walter

    2006-01-01

    The production of the dipole magnets for the Large Hadron Collider is at its final stage. Nevertheless, some mechanical instabilities are still observed for which no clear explanation has been found yet. A FE modelization of the dipole cold mass cross-section had already been developed at CERN, mainly for magnetic analysis, taking into account conductor blocks and a frictionless behavior. This paper describes a new ANSYS® model of the dipole coil cross-section, featuring individual turns inside conductor blocks, and implementing friction and the mechanical non-linear behavior of insulated cables. Preliminary results, comparison with measurements performed in industry and ongoing developments are discussed.

  11. High-resolution modeling assessment of tidal stream resource in Western Passage of Maine, USA

    Science.gov (United States)

    Yang, Zhaoqing; Wang, Taiping; Feng, Xi; Xue, Huijie; Kilcher, Levi

    2017-04-01

    Although significant efforts have been taken to assess the maximum potential of tidal stream energy at system-wide scale, accurate assessment of tidal stream energy resource at project design scale requires detailed hydrodynamic simulations using high-resolution three-dimensional (3-D) numerical models. Extended model validation against high quality measured data is essential to minimize the uncertainties of the resource assessment. Western Passage in the State of Maine in U.S. has been identified as one of the top ranking sites for tidal stream energy development in U.S. coastal waters, based on a number of criteria including tidal power density, market value and transmission distance. This study presents an on-going modeling effort for simulating the tidal hydrodynamics in Western Passage using the 3-D unstructured-grid Finite Volume Community Ocean Model (FVCOM). The model domain covers a large region including the entire the Bay of Fundy with grid resolution varies from 20 m in the Western Passage to approximately 1000 m along the open boundary near the mouth of Bay of Fundy. Preliminary model validation was conducted using existing NOAA measurements within the model domain. Spatial distributions of tidal power density were calculated and extractable tidal energy was estimated using a tidal turbine module embedded in FVCOM under different tidal farm scenarios. Additional field measurements to characterize resource and support model validation were discussed. This study provides an example of high resolution resource assessment based on the guidance recommended by the International Electrotechnical Commission Technical Specification.

  12. Modeling air quality in main cities of Peninsular Malaysia by using a generalized Pareto model.

    Science.gov (United States)

    Masseran, Nurulkamal; Razali, Ahmad Mahir; Ibrahim, Kamarulzaman; Latif, Mohd Talib

    2016-01-01

    The air pollution index (API) is an important figure used for measuring the quality of air in the environment. The API is determined based on the highest average value of individual indices for all the variables which include sulfur dioxide (SO2), nitrogen dioxide (NO2), carbon monoxide (CO), ozone (O3), and suspended particulate matter (PM10) at a particular hour. API values that exceed the limit of 100 units indicate an unhealthy status for the exposed environment. This study investigates the risk of occurrences of API values greater than 100 units for eight urban areas in Peninsular Malaysia for the period of January 2004 to December 2014. An extreme value model, known as the generalized Pareto distribution (GPD), has been fitted to the API values found. Based on the fitted model, return period for describing the occurrences of API exceeding 100 in the different cities has been computed as the indicator of risk. The results obtained indicated that most of the urban areas considered have a very small risk of occurrence of the unhealthy events, except for Kuala Lumpur, Malacca, and Klang. However, among these three cities, it is found that Klang has the highest risk. Based on all the results obtained, the air quality standard in urban areas of Peninsular Malaysia falls within healthy limits to human beings.

  13. Just value of the Tactebel energy: an valuation from the main models of pricing asset

    Directory of Open Access Journals (Sweden)

    Renato Campos

    2010-01-01

    Full Text Available This study aimed to determine the current fair value of Tractebel Energia, from the main asset pricing models. The company was taken as the object due to its stable growth and the ease of obtaining data, since it is located in the city of Florianopolis. Nevertheless, the volatility in its shares has been priced aroused interest. Therefore, this study intended to provide subsidy for the decision making of investors regarding the purchase or sale of company stock. For this, the theoretical treat on the concept of asset valuation and the main models available, emphasizing their applications and limitations, which are: assessment book on, discounted dividend model and discounted cash flow. Regarding the methodological aspect, the research fits into exploratory, descriptive, highly quantitative field study and case. Moreover, it was made use of desk research, literature, interview and program Economática. Thus, the analysis of data initially sought to raise the assumptions demanded by each of the models surveyed ad apply them. The results were then compared and adjusted so that there is consistency. He was later adopted an arithmetic mean to assign a fair value to the company. From this average was defined as an acceptance range, depending on the variability of results and uncertainty in the estimates.

  14. Automated main-chain model building by template matching and iterative fragment extension

    International Nuclear Information System (INIS)

    Terwilliger, Thomas C.

    2003-01-01

    A method for automated macromolecular main-chain model building is described. An algorithm for the automated macromolecular model building of polypeptide backbones is described. The procedure is hierarchical. In the initial stages, many overlapping polypeptide fragments are built. In subsequent stages, the fragments are extended and then connected. Identification of the locations of helical and β-strand regions is carried out by FFT-based template matching. Fragment libraries of helices and β-strands from refined protein structures are then positioned at the potential locations of helices and strands and the longest segments that fit the electron-density map are chosen. The helices and strands are then extended using fragment libraries consisting of sequences three amino acids long derived from refined protein structures. The resulting segments of polypeptide chain are then connected by choosing those which overlap at two or more C α positions. The fully automated procedure has been implemented in RESOLVE and is capable of model building at resolutions as low as 3.5 Å. The algorithm is useful for building a preliminary main-chain model that can serve as a basis for refinement and side-chain addition

  15. A Finite Element Model for Mechanical Analysis of LHC Main Dipole Magnet Coils

    CERN Document Server

    Pojer, Mirko; Scandale, Walter

    2007-01-01

    After years of studies and observations, the mechanical stability of the LHC main dipole magnets still remains an open issue. The robustness of these magnets has already been asserted and their reliability in operation is not far from being proven. However, anomalous mechanical behaviors sometimes observed are not yet completely understood. A finite element model, which has been recently developed at CERN, aims at providing an instrument for better explaining these anomalies. Cable modeling and contact between elements, friction and mechanical hysteresis are the key features of this model. The simulation of the hysteresis experienced by the coil during collaring, presented here, is the starting point for the representation of the whole life cycle of the dipole coil.

  16. A model for the Space Shuttle Main Engine High Pressure Oxidizer Turbopump shaft seal system

    Science.gov (United States)

    Paxson, Daniel E.

    1990-01-01

    A model of the High Pressure Oxidizer Turbopump (HPOTP) shaft seal system on the Space Shuttle Main Engine (SSME) is described. The model predicts the fluid properties and flow rates throughout this system for a number of conditions simulating failed seals. The results agree well with qualitative expectations and redline values but cannot be verified with actual data due to the lack thereof. The results indicate that each failure mode results in a unique distribution of properties throughout the seal system and can therefore be individually identified given the proper instrumentation. Furthermore, the detection process can be built on the principle of qualitative reasoning without the use of exact fluid property values. A simplified implementation of the model which does not include the slinger/labyrinth seal combination has been developed and will be useful for inclusion in a real-time diagnostic system.

  17. Comparison of effectiveness of advertising expenses during broadcasts of main hockey events

    OpenAIRE

    Kozlová, Natálie

    2017-01-01

    Title: Comparison of effectiveness of advertising expenses during broadcasts of main hockey events Objectives: The main goal of this dissertation is to compare the amount of money invested into the commercial advertisement during sport broadcasts at the ČT sport channel with viewer ratings. The used metric is a coefficient computed as a ratio between the viewer rating of the particular broadcast and the corresponding advertisement cost, normalized using Cost per Thousand method. Another goal ...

  18. Protoscolecidal Effect of Berberis vulgaris Root Extract and Its Main Compound, Berberine in Cystic Echinococcosis.

    Directory of Open Access Journals (Sweden)

    Hossein Mahmoudvand

    2014-12-01

    Full Text Available Cystic echinococcosis (CE, a zoonotic parasitic infection caused by the metacestode (larvae stage of dog tapeworm Echinococcus granulosus and recognized as a major economic and public health concern in the world. This study aimed to investigate the in vitro scolicidal effect of methanolic extract of Berberis vulgaris L. roots and its main compound, berberine against protoscoleces of hydatid cysts.For this purpose, protoscoleces were aseptically aspirated from sheep livers having hydatid cysts. Various concentrations of the methanolic extract (0.25-2 mg/ml and berberine (0.062- 0.5 mg/ml were used for 5 to 30 min. Viability of protoscoleces was confirmed by eosin exclusive test.In the present study, all of the various concentrations of the B. vulgaris methanolic extract (0.25, 0.5, 1 and 2 mg/ml and berberine (0.062, 0.125, 0.25 and 0.5 mg/ml revealed significant (P<0.05 scolicidal effects against protoscoleces of E. granulosus in a dose-dependent manner. Both berberine and methanolic extract exhibited 100% inhibition against protoscoleces of E. granulosus at the concentration of 2.0 and 0.5 mg/ml after 10 min incubation, respectively.According to the results, both B. vulgaris methanolic extract and berberine alone demonstrated high scolicidal activities against protoscoleces of hydatid cysts in low concentration and short exposure time on in vitro model. However, in vivo efficacy of B. vulgaris and berberine also requires to be evaluated using an animal model with hydatid infection.

  19. Purpose-in-Life Test: Comparison of the Main Models in Patients with Mental Disorders.

    Science.gov (United States)

    García-Alandete, Joaquín; Marco, José H; Pérez, Sandra

    2017-06-27

    The aim of this study was to compare the main proposed models for the Purpose-In-Life Test, a scale for assessing meaning in life, in 229 Spanish patients with mental disorders (195 females and 34 males, aged 13-68, M = 34.43, SD = 12.19). Confirmatory factor-analytic procedures showed that the original model of the Purpose-In-Life Test, a 20-item unidimensional scale, obtained a better fit than the other analyzed models, SBχ2(df) = 326.27(170), SBχ2/df = 1.92, TLI = .93, CFI = .94, IFI = .94, RMSEA = .063 (90% CI [.053, .074]), CAIC = -767.46, as well as a high internal consistency, (α = .90). The main conclusion is that the original version of the Purpose-In-Life shows a robust construct validity in a clinical population. However, authors recommend an in-depth psychometric analysis of the Purpose-In-Life Test among clinical population. Likewise, the importance of assessing meaning in life in order to enhance psychotherapeutic treatment is noted.

  20. Main steam line break accident simulation of APR1400 using the model of ATLAS facility

    Science.gov (United States)

    Ekariansyah, A. S.; Deswandri; Sunaryo, Geni R.

    2018-02-01

    A main steam line break simulation for APR1400 as an advanced design of PWR has been performed using the RELAP5 code. The simulation was conducted in a model of thermal-hydraulic test facility called as ATLAS, which represents a scaled down facility of the APR1400 design. The main steam line break event is described in a open-access safety report document, in which initial conditions and assumptionsfor the analysis were utilized in performing the simulation and analysis of the selected parameter. The objective of this work was to conduct a benchmark activities by comparing the simulation results of the CESEC-III code as a conservative approach code with the results of RELAP5 as a best-estimate code. Based on the simulation results, a general similarity in the behavior of selected parameters was observed between the two codes. However the degree of accuracy still needs further research an analysis by comparing with the other best-estimate code. Uncertainties arising from the ATLAS model should be minimized by taking into account much more specific data in developing the APR1400 model.

  1. The Construction of Intensive and Organized Agricultural Industrialization Model with Farmers as the Main Body

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    The current agricultural conflicts of China are analyzed and the forms and drawbacks of current agricultural industrial structure are listed.The situations for intensifying the farmland with appropriate scale are analyzed from the aspects of policy,farmers,farms and modernization of agriculture.It is pointed out that the situations for the intensive use of land are becoming mature.Taking the single pig-breeding chain as an example,the agricultural industrialization model,which takes farmers as the main body,is expounded.Besides,its functions and significance in solving "the three agriculture problems" and facilitating the modernization of agriculture are discussed.

  2. Dynamic models of reduced order of main components of a M SR

    International Nuclear Information System (INIS)

    Garcia B, F. B.; Morales S, J. B.; Polo L, M. A.; Espinosa P, G.

    2011-11-01

    The reactors of melted salts called Molten Salt Fast Reactor (MSFR), have seen a resurgence of interest in the last decade. This design is one of the six proposed for the IV generation reactors. The most active development was in the middle of 1950 and principles of 1970 in the Oak Ridge National Laboratories (ORNL). In this work the mathematician modeling of the main components in the primary and secondary circuits of a M SR is presented. In particular the dynamics of the heat exchanger is analyzed and they are considered several materials to optimize the system thermodynamically. (Author)

  3. Modeling Main Body of Overcrossing Bridge Based on Vehicle-Borne Laser Scanning Data

    Science.gov (United States)

    Chen, X.; Chen, M.; Wei, Z.; Zhong, R.

    2017-09-01

    Vehicle-borne laser scanning (VBLS) is widely used to collect urban data for various mapping and modelling systems. This paper proposes a strategy of feature extraction and 3d model reconstruction for main body of overcrossing bridges based on VBLS point clouds. As the bridges usually have a large span, and the clouds data is often affected by obstacles, we have to use round-trip cloud data to avoid missing part. To begin with, pick out the cloud of the bridge body by an interactive clip-box, and group points by scan-line, then sort the points by scanning angle on each scan line. Since the position under the vehicle have a fixed scan-angle, a virtual path can be obtained. Secondly, extract horizontal line segments perpendicular to the virtual path along adjacent scan-lines, and then cluster line segments into long line-strings, which represent the top and bottom edge. Finally, regularize the line-strings and build 3d surface model of the bridge body. Experimental studies have demonstrated its efficiency and accuracy in case of building bridge model. Modelling the stairs at the both end of the bridge will be the direction of the next step.

  4. MODELING MAIN BODY OF OVERCROSSING BRIDGE BASED ON VEHICLE-BORNE LASER SCANNING DATA

    Directory of Open Access Journals (Sweden)

    X. Chen

    2017-09-01

    Full Text Available Vehicle-borne laser scanning (VBLS is widely used to collect urban data for various mapping and modelling systems. This paper proposes a strategy of feature extraction and 3d model reconstruction for main body of overcrossing bridges based on VBLS point clouds. As the bridges usually have a large span, and the clouds data is often affected by obstacles, we have to use round-trip cloud data to avoid missing part. To begin with, pick out the cloud of the bridge body by an interactive clip-box, and group points by scan-line, then sort the points by scanning angle on each scan line. Since the position under the vehicle have a fixed scan-angle, a virtual path can be obtained. Secondly, extract horizontal line segments perpendicular to the virtual path along adjacent scan-lines, and then cluster line segments into long line-strings, which represent the top and bottom edge. Finally, regularize the line-strings and build 3d surface model of the bridge body. Experimental studies have demonstrated its efficiency and accuracy in case of building bridge model. Modelling the stairs at the both end of the bridge will be the direction of the next step.

  5. Modeling of a dependence between human operators in advanced main control rooms

    International Nuclear Information System (INIS)

    Lee, Seung Jun; Kim, Jaewhan; Jang, Seung-Cheol; Shin, Yeong Cheol

    2009-01-01

    For the human reliability analysis of main control room (MCR) operations, not only parameters such as the given situation and capability of the operators but also the dependence between the actions of the operators should be considered because MCR operations are team operations. The dependence between operators might be more prevalent in an advanced MCR in which operators share the same information using a computerized monitoring system or a computerized procedure system. Therefore, this work focused on the computerized operation environment of advanced MCRs and proposed a model to consider the dependence representing the recovery possibility of an operator error by another operator. The proposed model estimates human error probability values by considering adjustment values for a situation and dependence values for operators during the same operation using independent event trees. This work can be used to quantitatively calculate a more reliable operation failure probability for an advanced MCR. (author)

  6. A simple 2D SOC model for one of the main sources of geomagnetic disturbances: Flares

    International Nuclear Information System (INIS)

    Meirelles, M.C.; Dias, V.H.A.; Oliva, D.; Papa, A.R.R.

    2010-01-01

    We introduce a simple model for solar flares, one of the main sources of geomagnetic disturbances. We have obtained power-laws for the probability distribution functions of some relevant physical characteristics of flares which could serve as the fingerprint of a critical state at the base of such phenomena and, given that we have not introduced a fine tune mechanism, of self-organized criticality. We compare our results with some recent experimental work on the statistics of flares and analyze the possible connection of these power laws with others already found by our group in geomagnetic disturbances distributions. We also present some limitations of our model as well as possible extensions and corrections to be taken into account in future works.

  7. Modelling the Earth's Main Magnetic Field by the spinning Astrid-2 satellite

    DEFF Research Database (Denmark)

    Merayo, Jose Maria Garcia; Jørgensen, Peter Siegbjørn; Risbo, T.

    1999-01-01

    and therefore the mapping of the Earth's magnetic field may be possible. The spinning of the spacecraft about a certain axis makes the stabilisation in space possible. This fact and the well distributed data over the globe makes the magnetic data well suited for the estimation of the magnetic field model......The Swedish micro-satellite Astrid-2 was successfully launched into a near polar orbit last December 98. Despite the fact that its primary mission was the research of Auroral phenomena, the magnetic instrumentation has been designed to accomplish high resolution vector field magnetic measurements...... at the spacecraft altitude (circa 1000km). Several methods for field modelling are presented in this paper with the assumption that the direction of the spin axis is nearly constant. In any case the orientation of the magnetometer is to bedetermined simultaneously with the instrument calibration and main field...

  8. Social exposure and emotion dysregulation: Main effects in relation to nonsuicidal self-injury.

    Science.gov (United States)

    Zelkowitz, Rachel L; Porter, Andrew C; Heiman, Ellen R; Cole, David A

    2017-10-01

    We examined the relation of interpersonal and media exposure to nonsuicidal self-injury (NSSI) among 340 university students in the southeastern United States (73.5% female, M age = 19.38 years, SD = 1.15). We also assessed interactions and main effects of each exposure and emotion dysregulation in relation to NSSI, testing the social learning hypothesis of NSSI. Most participants endorsed medium to high levels of exposure to NSSI via media sources. More than one-third of participants were somewhat or very familiar with someone who engaged in NSSI. Almost half reported occasional or frequent conversations about NSSI. Both exposure forms were significantly related to NSSI history. However, hurdle regression analyses revealed that interpersonal exposure and emotion dysregulation, but not media exposure, were significantly associated with NSSI history and frequency. We did not find evidence for an emotion dysregulation-by-interpersonal-exposure interaction. We discuss implications for theoretical models of NSSI, limitations, and future directions. Copyright © 2017. Published by Elsevier Ltd.

  9. Reliability model for helicopter main gearbox lubrication system using influence diagrams

    International Nuclear Information System (INIS)

    Rashid, H.S.J.; Place, C.S.; Mba, D.; Keong, R.L.C.; Healey, A.; Kleine-Beek, W.; Romano, M.

    2015-01-01

    The loss of oil from a helicopter main gearbox (MGB) leads to increased friction between components, a rise in component surface temperatures, and subsequent mechanical failure of gearbox components. A number of significant helicopter accidents have been caused due to such loss of lubrication. This paper presents a model to assess the reliability of helicopter MGB lubricating systems. Safety risk modeling was conducted for MGB oil system related accidents in order to analyse key failure mechanisms and the contributory factors. Thus, the dominant failure modes for lubrication systems and key contributing components were identified. The Influence Diagram (ID) approach was then employed to investigate reliability issues of the MGB lubrication systems at the level of primary causal factors, thus systematically investigating a complex context of events, conditions, and influences that are direct triggers of the helicopter MGB lubrication system failures. The interrelationships between MGB lubrication system failure types were thus identified, and the influence of each of these factors on the overall MGB lubrication system reliability was assessed. This paper highlights parts of the HELMGOP project, sponsored by the European Aviation Safety Agency to improve helicopter main gearbox reliability. - Highlights: • We investigated methods to optimize helicopter MGB oil system run-dry capability. • Used Influence Diagram to assess design and maintenance factors of MGB oil system. • Factors influencing overall MGB lubrication system reliability were identified. • This globally influences current and future helicopter MGB designs

  10. Main concepts and objectives of fuel performance modelling and core development

    International Nuclear Information System (INIS)

    Lassmann, K.; O'Carroll, C.; Van de Laar, J.; Ray, I.

    1994-01-01

    The basic concepts of the fuel rod modelling was reviewed and their limitations are discussed.Three more general modelling concepts are briefly outlined: one-dimensional models versus 2-D or 3-D models; steady-state versus transient modelling; empirical versus mechanical models. The fuel rod behaviour is determined by thermal, mechanical and physical processes such as densification, swelling, gas release, irradiation damage etc. It is shown that the macroscopic behaviour of a fuel rod is to a large extent determined by the local UO 2 microstructure. Any fuel rod model must include the solution of the heat conduction equation and the principal mechanical equations i. e. equilibrium and compatibility, together with constitutive equations. The basic limitations from the different assumptions made for the solution of the governing equations are identified. It was shown that the thermal and the mechanical analysis are strongly coupled and therefore errors are propagated. The individual correlations and processes are also not error-free and in only some cases can individual errors be estimated. There is almost for all processes a good understanding of the dominating parameters but the unsolved problem is how local quantities such as pores and grain structure, stresses etc. evolve during the irradiation. Thus the wrong input data for local processes is considered as one of the main source of uncertainty. Fission gas release and swelling could not be described by the corresponding equations without introducing some free parameters. The center line predictions of two codes for FUMEX blind exercise are given. It is stated that since the D-COM exercise in 1984, fuel rod performance codes have been improved considerably and must be now considered as mature tools for further optimisation of fuel rods. 1 tab., 12 figs., 22 refs

  11. Main concepts and objectives of fuel performance modelling and core development

    Energy Technology Data Exchange (ETDEWEB)

    Lassmann, K; O` Carroll, C; Van de Laar, J; Ray, I [Commission of the European Communities, Karlsruhe (Germany). European Inst. for Transuranium Elements; Stefanova, S [Bylgarska Akademiya na Naukite, Sofia (Bulgaria). Inst. za Yadrena Izsledvaniya i Yadrena Energetika; Chantoin, P [International Atomic Energy Agency, Vienna (Austria)

    1994-12-31

    The basic concepts of the fuel rod modelling was reviewed and their limitations are discussed.Three more general modelling concepts are briefly outlined: one-dimensional models versus 2-D or 3-D models; steady-state versus transient modelling; empirical versus mechanical models. The fuel rod behaviour is determined by thermal, mechanical and physical processes such as densification, swelling, gas release, irradiation damage etc. It is shown that the macroscopic behaviour of a fuel rod is to a large extent determined by the local UO{sub 2} microstructure. Any fuel rod model must include the solution of the heat conduction equation and the principal mechanical equations i. e. equilibrium and compatibility, together with constitutive equations. The basic limitations from the different assumptions made for the solution of the governing equations are identified. It was shown that the thermal and the mechanical analysis are strongly coupled and therefore errors are propagated. The individual correlations and processes are also not error-free and in only some cases can individual errors be estimated. There is almost for all processes a good understanding of the dominating parameters but the unsolved problem is how local quantities such as pores and grain structure, stresses etc. evolve during the irradiation. Thus the wrong input data for local processes is considered as one of the main source of uncertainty. Fission gas release and swelling could not be described by the corresponding equations without introducing some free parameters. The center line predictions of two codes for FUMEX blind exercise are given. It is stated that since the D-COM exercise in 1984, fuel rod performance codes have been improved considerably and must be now considered as mature tools for further optimisation of fuel rods. 1 tab., 12 figs., 22 refs.

  12. Main modelling features of the ASTEC V2.1 major version

    International Nuclear Information System (INIS)

    Chatelard, P.; Belon, S.; Bosland, L.; Carénini, L.; Coindreau, O.; Cousin, F.; Marchetto, C.; Nowack, H.; Piar, L.; Chailan, L.

    2016-01-01

    Highlights: • Recent modelling improvements of the ASTEC European severe accident code are outlined. • Key new physical models now available in the ASTEC V2.1 major version are described. • ASTEC progress towards a multi-design reactor code is illustrated for BWR and PHWR. • ASTEC strong link with the on-going EC CESAM FP7 project is emphasized. • Main remaining modelling issues (on which IRSN efforts are now directing) are given. - Abstract: A new major version of the European severe accident integral code ASTEC, developed by IRSN with some GRS support, was delivered in November 2015 to the ASTEC worldwide community. Main modelling features of this V2.1 version are summarised in this paper. In particular, the in-vessel coupling technique between the reactor coolant system thermal-hydraulics module and the core degradation module has been strongly re-engineered to remove some well-known weaknesses of the former V2.0 series. The V2.1 version also includes new core degradation models specifically addressing BWR and PHWR reactor types, as well as several other physical modelling improvements, notably on reflooding of severely damaged cores, Zircaloy oxidation under air atmosphere, corium coolability during corium concrete interaction and source term evaluation. Moreover, this V2.1 version constitutes the back-bone of the CESAM FP7 project, which final objective is to further improve ASTEC for use in Severe Accident Management analysis of the Gen.II–III nuclear power plants presently under operation or foreseen in near future in Europe. As part of this European project, IRSN efforts to continuously improve both code numerical robustness and computing performances at plant scale as well as users’ tools are being intensified. Besides, ASTEC will continue capitalising the whole knowledge on severe accidents phenomenology by progressively keeping physical models at the state of the art through a regular feed-back from the interpretation of the current and

  13. Imitative modeling automatic system Control of steam pressure in the main steam collector with the influence on the main Servomotor steam turbine

    Science.gov (United States)

    Andriushin, A. V.; Zverkov, V. P.; Kuzishchin, V. F.; Ryzhkov, O. S.; Sabanin, V. R.

    2017-11-01

    The research and setting results of steam pressure in the main steam collector “Do itself” automatic control system (ACS) with high-speed feedback on steam pressure in the turbine regulating stage are presented. The ACS setup is performed on the simulation model of the controlled object developed for this purpose with load-dependent static and dynamic characteristics and a non-linear control algorithm with pulse control of the turbine main servomotor. A method for tuning nonlinear ACS with a numerical algorithm for multiparametric optimization and a procedure for separate dynamic adjustment of control devices in a two-loop ACS are proposed and implemented. It is shown that the nonlinear ACS adjusted with the proposed method with the regulators constant parameters ensures reliable and high-quality operation without the occurrence of oscillations in the transient processes the operating range of the turbine loads.

  14. Variational data assimilative modeling of the Gulf of Maine in spring and summer 2010

    Science.gov (United States)

    Li, Yizhen; He, Ruoying; Chen, Ke; McGillicuddy, Dennis J.

    2015-05-01

    A data assimilative ocean circulation model is used to hindcast the Gulf of Maine [GOM) circulation in spring and summer 2010. Using the recently developed incremental strong constraint 4D Variational data assimilation algorithm, the model assimilates satellite sea surface temperature and in situ temperature and salinity profiles measured by expendable bathythermograph, Argo floats, and shipboard CTD casts. Validation against independent observations shows that the model skill is significantly improved after data assimilation. The data-assimilative model hindcast reproduces the temporal and spatial evolution of the ocean state, showing that a sea level depression southwest of the Scotian Shelf played a critical role in shaping the gulf-wide circulation. Heat budget analysis further demonstrates that both advection and surface heat flux contribute to temperature variability. The estimated time scale for coastal water to travel from the Scotian Shelf to the Jordan Basin is around 60 days, which is consistent with previous estimates based on in situ observations. Our study highlights the importance of resolving upstream and offshore forcing conditions in predicting the coastal circulation in the GOM.

  15. Main Memory

    NARCIS (Netherlands)

    P.A. Boncz (Peter); L. Liu (Lei); M. Tamer Özsu

    2008-01-01

    htmlabstractPrimary storage, presently known as main memory, is the largest memory directly accessible to the CPU in the prevalent Von Neumann model and stores both data and instructions (program code). The CPU continuously reads instructions stored there and executes them. It is also called Random

  16. Ordinary Social Interaction and the Main Effect Between Perceived Support and Affect.

    Science.gov (United States)

    Lakey, Brian; Vander Molen, Randy J; Fles, Elizabeth; Andrews, Justin

    2016-10-01

    Relational regulation theory hypothesizes that (a) the main effect between perceived support and mental health primarily reflects ordinary social interaction rather than conversations about stress and how to cope with it, and (b) the extent to which a provider regulates a recipient's mental health primarily reflects the recipient's personal taste (i.e., is relational), rather than the provider's objective supportiveness. In three round-robin studies, participants rated each other on supportiveness and the quality of ordinary social interaction, as well as their own affect when interacting with each other. Samples included marines about to deploy to Afghanistan (N = 100; 150 dyads), students sharing apartments (N = 64; 96 dyads), and strangers (N = 48; 72 dyads). Perceived support and ordinary social interaction were primarily relational, and most of perceived support's main effect on positive affect was redundant with ordinary social interaction. The main effect between perceived support and affect emerged among strangers after brief text conversations, and these links were partially verified by independent observers. Findings for negative affect were less consistent with theory. Ordinary social interaction appears to be able to explain much of the main effect between perceived support and positive affect. © 2015 Wiley Periodicals, Inc.

  17. Automated main-chain model building by template matching and iterative fragment extension.

    Science.gov (United States)

    Terwilliger, Thomas C

    2003-01-01

    An algorithm for the automated macromolecular model building of polypeptide backbones is described. The procedure is hierarchical. In the initial stages, many overlapping polypeptide fragments are built. In subsequent stages, the fragments are extended and then connected. Identification of the locations of helical and beta-strand regions is carried out by FFT-based template matching. Fragment libraries of helices and beta-strands from refined protein structures are then positioned at the potential locations of helices and strands and the longest segments that fit the electron-density map are chosen. The helices and strands are then extended using fragment libraries consisting of sequences three amino acids long derived from refined protein structures. The resulting segments of polypeptide chain are then connected by choosing those which overlap at two or more C(alpha) positions. The fully automated procedure has been implemented in RESOLVE and is capable of model building at resolutions as low as 3.5 A. The algorithm is useful for building a preliminary main-chain model that can serve as a basis for refinement and side-chain addition.

  18. Internal lecture: The dawn of the Standard Model's revolution | 6 June | Main Auditorium

    CERN Multimedia

    2014-01-01

    "The dawn of the Standard Model's revolution", by Luigi di Lella and Alvaro de Rujula.   Alvaro de Rujula. 15:30 - 16:20: Lecture by Alvaro de Rujula (followed by 20 minutes of questions) Abstract In the few years around November 1974, particle physics changed very significantly and at a frantic pace. Practitioners began to get accustomed to the successful predictions of the Standard Model, which did not have many believers at that time. I shall recall the main experimental and theoretical advances, concerning in particular quarks as partons, the asymptotic freedom of QCD, charmonia and the first openly charmed particles. Career Alvaro de Rújula was at Harvard University during the Standard Model revolution. Before and after, amongst many other places, he worked at CERN.   16:40 - 17:00: Coffee break   Luigi di Lella. 17:00 - 17:50: Lecture by Luigi di Lella: Experiments at CERN in the decade 1964-1974 (followed by 20 minut...

  19. Effects of gamma-irradiation on the main nutritional composition of rape pollen

    International Nuclear Information System (INIS)

    Lu Yuan; Wang Darui; Han Denbao; Liu Deshen

    1990-01-01

    Storaged pollen is easy to be destroyed by bacterium, moulds and insects. In order to solve this problem we tried to irradiate pollen with doses of 1.5 kGy and 2.5 kGy of γ-rays and then analyse its main nutritional compositions so to find out the effects of gamma-irradiation on amino acids, protein, carbohydrate, fat, vitamines etc. The results have been showed that the above doses gamma-irradiation doesn't notably influence the main nutritional compositions of rape pollen, even if they are storaged for three or six months at 4 deg C

  20. Making Sense of Atmospheric Models and Fundamental Stellar Properties at the Bottom of the Main Sequence

    Science.gov (United States)

    Dieterich, Sergio; Henry, Todd; Jao, W.-C.; Washington, Robert; Silverstein, Michele; Winters, J.; RECONS

    2018-01-01

    We present a detailed comparison of atmospheric model predictions and photometric observations for late M and L dwarfs. We discuss which wavelength regions are best for determining the fundamental properties of these cool stellar and substellar atmospheres and use this analysis to refine the HR diagram for the hydrogen burning limit first presented in 2014. We also add several new objects to the HR diagram and find little qualitative difference in the HR diagram's overall morphology when compared to our 2014 results. The L2 dwarf 2MASS 0523-1403 remains the smallest hydrogen burning star for which we calculated a radius, thus likely indicating the end of the stellar main sequence. This work is supported by the NSF Astronomy and Astrophysics Postdoctoral Fellowship program through grant AST-1400680.

  1. The Effect of Acoustic Disturbances on the Operation of the Space Shuttle Main Engine Fuel Flowmeter

    Science.gov (United States)

    Marcu, Bogdan; Szabo, Roland; Dorney, Dan; Zoladz, Tom

    2007-01-01

    The Space Shuttle Main Engine (SSME) uses a turbine fuel flowmeter (FFM) in its Low Pressure Fuel Duct (LPFD) to measure liquid hydrogen flowrates during engine operation. The flowmeter is required to provide accurate and robust measurements of flow rates ranging from 10000 to 18000 GPM in an environment contaminated by duct vibration and duct internal acoustic disturbances. Errors exceeding 0.5% can have a significant impact on engine operation and mission completion. The accuracy of each sensor is monitored during hot-fire engine tests on the ground. Flow meters which do not meet requirements are not flown. Among other parameters, the device is screened for a specific behavior in which a small shift in the flow rate reading is registered during a period in which the actual fuel flow as measured by a facility meter does not change. Such behavior has been observed over the years for specific builds of the FFM and must be avoided or limited in magnitude in flight. Various analyses of the recorded data have been made prior to this report in an effort to understand the cause of the phenomenon; however, no conclusive cause for the shift in the instrument behavior has been found. The present report proposes an explanation of the phenomenon based on interactions between acoustic pressure disturbances in the duct and the wakes produced by the FFM flow straightener. Physical insight into the effects of acoustic plane wave disturbances was obtained using a simple analytical model. Based on that model, a series of three-dimensional unsteady viscous flow computational fluid dynamics (CFD) simulations were performed using the MSFC PHANTOM turbomachinery code. The code was customized to allow the FFM rotor speed to change at every time step according to the instantaneous fluid forces on the rotor, that, in turn, are affected by acoustic plane pressure waves propagating through the device. The results of the simulations show the variation in the rotation rate of the flowmeter

  2. Main and combined effects of musculoskeletal pain frequency and avoidant coping on sickness absence

    DEFF Research Database (Denmark)

    Christensen, Ulla; Schmidt, Lone; Hougaard, Charlotte Orsted

    2013-01-01

    Objective: Musculoskeletal pain and avoidant coping predicts sickness absence, but how these 2 predictors relate to each other is unknown. We examined the main and combined effects of musculoskeletal pain and avoidant, behavioural coping on incidence of sickness absence. Design and subjects......: Prospective cohort study of a sample of middle-aged Danes, economically active in 2006, reporting functional limitations due to musculoskeletal pain, n = 3115. Methods: Data included surveys from 2000 and 2006 and register data from 2007. Outcome was sickness absence exceeding 2 consecutive weeks in 2007....... The main effect of self-reported pain frequency and avoidant coping on sickness absence was analysed by multivariate logistic regression. The combined effect was calculated as departure from multiplicativity and by the inclusion of a product term. Results: Daily pain and use of avoidant coping were both...

  3. COSYMA: Health effects models

    International Nuclear Information System (INIS)

    Ehrhardt, J.

    1995-02-01

    As one of the main objectives of the MARIA project (''Methods for Assessing the Radiological Impact of Accidents'') initiated by the Commission of the European Communities the program package COSYMA (''COde SYstem from MARIA'') for assessing the radiological and economic off-site consequences of accidental releases of radioactive material to the atmosphere has been jointly developed by the Kernforschungszentrum Karlsruhe (KfK), FRG, and the National Radiological Protection Board (NRPB), UK. COSYMA includes models and data for assessing a broad spectrum of accident consequences, and they are implemented in independent modules. The subject of this report are those modules, which incorporate models and data for assessing individual and collective risks for deterministic and stochastic health effects. It describes the models implemented, the mathematical algorithms and the required data. Examples are given and explained for the input and output part of the modules. (orig.)

  4. High Resolution Modelling of the Congo River's Multi-Threaded Main Stem Hydraulics

    Science.gov (United States)

    Carr, A. B.; Trigg, M.; Tshimanga, R.; Neal, J. C.; Borman, D.; Smith, M. W.; Bola, G.; Kabuya, P.; Mushie, C. A.; Tschumbu, C. L.

    2017-12-01

    We present the results of a summer 2017 field campaign by members of the Congo River users Hydraulics and Morphology (CRuHM) project, and a subsequent reach-scale hydraulic modelling study on the Congo's main stem. Sonar bathymetry, ADCP transects, and water surface elevation data have been collected along the Congo's heavily multi-threaded middle reach, which exhibits complex in-channel hydraulic processes that are not well understood. To model the entire basin's hydrodynamics, these in-channel hydraulic processes must be parameterised since it is not computationally feasible to represent them explicitly. Furthermore, recent research suggests that relative to other large global rivers, in-channel flows on the Congo represent a relatively large proportion of total flow through the river-floodplain system. We therefore regard sufficient representation of in-channel hydraulic processes as a Congo River hydrodynamic research priority. To enable explicit representation of in-channel hydraulics, we develop a reach-scale (70 km), high resolution hydraulic model. Simulation of flow through individual channel threads provides new information on flow depths and velocities, and will be used to inform the parameterisation of a broader basin-scale hydrodynamic model. The basin-scale model will ultimately be used to investigate floodplain fluxes, flood wave attenuation, and the impact of future hydrological change scenarios on basin hydrodynamics. This presentation will focus on the methodology we use to develop a reach-scale bathymetric DEM. The bathymetry of only a small proportion of channel threads can realistically be captured, necessitating some estimation of the bathymetry of channels not surveyed. We explore different approaches to this bathymetry estimation, and the extent to which it influences hydraulic model predictions. The CRuHM project is a consortium comprising the Universities of Kinshasa, Rhodes, Dar es Salaam, Bristol, and Leeds, and is funded by Royal

  5. Effect of main stem pruning and fruit thinning on the postharvest conservation of melon

    Directory of Open Access Journals (Sweden)

    Rafaella M. de A. Ferreira

    Full Text Available ABSTRACT Main stem pruning and fruit thinning are cultivation practices that can influence the yield and quality of the fruit. This study aimed to evaluate the effects of main stem pruning and fruit thinning on the postharvest conservation of Charentais Banzai melons. In the field, the plants were subjected to main stem pruning and fruit thinning, with harvesting done 74 days after sowing (DAS. The fruits were transported to the laboratory where they were cleaned, characterized, and stored in a cold chamber (5 °C and 90 ± 2% RH. In the field, the experiment was designed as a split-plot using a 2 × 4 + 1 factorial design, with two levels of main stem pruning (pruned and unpruned, four levels of thinning times (42, 45, 48, and 51 DAS, and a control (unpruned and unthinned. The sub-plot consisted of storage times (0, 7, 14, 21, and 28 days, with four blocks. The preharvest treatments did not significantly influence the production characteristics of the Banzai hybrid. The treatment without pruning increased the titratable acidity of fruit, and the thinning at 51 days after sowing (DAS reduced soluble sugars. There was a decline in pulp firmness, titratable acidity, reducing sugars, and an increase in soluble solids, total soluble sugar, and non-reducing sugars during storage. Pruning the main melon stem reduced the weight loss of the fruit after 28 days of storage.

  6. Gastroprotective effect of the Mapuche crude drug Araucaria araucana resin and its main constituents.

    Science.gov (United States)

    Schmeda-Hirschmann, Guillermo; Astudillo, Luis; Rodríguez, Jaime; Theoduloz, Cristina; Yáñez, Tania

    2005-10-03

    The resin from the tree Araucaria araucana (Araucariaceae) has been used since pre-columbian times by the Mapuche amerindians to treat ulcers. The gastroprotective effect of the resin was assessed in the ethanol-HCl-induced gastric ulcer in mice showing a dose-dependent gastroprotective activity at 100, 200 and 300 mg/kg per os. The main three diterpene constituents of the resin, namely imbricatolic acid, 15-hydroxyimbricatolal and 15-acetoxyimbricatolic acid were isolated and evaluated for gastroprotective effect at doses of 50, 100 and 200 mg/kg. A dose-related gastroprotective effect with highly significant activity (PMapuche culture.

  7. A Preliminary Investigation of Maine Virtual Charter School Costs Relative to the Essential Programs and Services Funding Model

    Science.gov (United States)

    Johnson, Amy F.; Hopper, Fleur; Sloan, James E.

    2016-01-01

    In 2015, the Maine State Legislature's Joint Standing Committee on Education and Cultural Affairs commissioned the Maine Education Policy Research Institute (MEPRI) to study the state's Essential Program and Services (EPS) K-12 education funding model in relationship to the funding for Maine's two virtual charter schools. The study was initiated…

  8. Main Effect QTL with Dominance Determines Heterosis for Dynamic Plant Height in Upland Cotton

    Directory of Open Access Journals (Sweden)

    Lianguang Shang

    2016-10-01

    Full Text Available Plant height, which shows dynamic development and heterosis, is a major trait affecting plant architecture and has an indirect influence on economic yield related to biological yield in cotton. In the present study, we carried out dynamic analysis for plant height and its heterosis by quantitative trait loci (QTL mapping at multiple developmental stages using two recombinant inbred lines (RILs and their backcross progeny. At the single-locus level, 47 QTL were identified at five developmental stages in two hybrids. In backcross populations, QTL identified at an early stage mainly showed partial effects and QTL detected at a later stage mostly displayed overdominance effects. At the two-locus level, we found that main effect QTL played a more important role than epistatic QTL in the expression of heterosis in backcross populations. Therefore, this study implies that the genetic basis of plant height heterosis shows dynamic character and main effect QTL with dominance determines heterosis for plant height in Upland cotton.

  9. Evolution Models of Helium White Dwarf–Main-sequence Star Merger Remnants

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Xianfei; Bi, Shaolan [Department of Astronomy, Beijing Normal University, Beijing, 100875 (China); Hall, Philip D.; Jeffery, C. Simon, E-mail: zxf@bnu.edu.cn [Armagh Observatory, College Hill, Armagh BT61 9DG (United Kingdom)

    2017-02-01

    It is predicted that orbital decay by gravitational-wave radiation and tidal interaction will cause some close binary stars to merge within a Hubble time. The merger of a helium-core white dwarf with a main-sequence (MS) star can produce a red giant branch star that has a low-mass hydrogen envelope when helium is ignited and thus become a hot subdwarf. Because detailed calculations have not been made, we compute post-merger models with a stellar evolution code. We find the evolutionary paths available to merger remnants and find the pre-merger conditions that lead to the formation of hot subdwarfs. We find that some such mergers result in the formation of stars with intermediate helium-rich surfaces. These stars later develop helium-poor surfaces owing to diffusion. Combining our results with a model population and comparing to observed stars, we find that some observed intermediate helium-rich hot subdwarfs can be explained as the remnants of the mergers of helium-core white dwarfs with low-mass MS stars.

  10. Evolution Models of Helium White Dwarf–Main-sequence Star Merger Remnants

    International Nuclear Information System (INIS)

    Zhang, Xianfei; Bi, Shaolan; Hall, Philip D.; Jeffery, C. Simon

    2017-01-01

    It is predicted that orbital decay by gravitational-wave radiation and tidal interaction will cause some close binary stars to merge within a Hubble time. The merger of a helium-core white dwarf with a main-sequence (MS) star can produce a red giant branch star that has a low-mass hydrogen envelope when helium is ignited and thus become a hot subdwarf. Because detailed calculations have not been made, we compute post-merger models with a stellar evolution code. We find the evolutionary paths available to merger remnants and find the pre-merger conditions that lead to the formation of hot subdwarfs. We find that some such mergers result in the formation of stars with intermediate helium-rich surfaces. These stars later develop helium-poor surfaces owing to diffusion. Combining our results with a model population and comparing to observed stars, we find that some observed intermediate helium-rich hot subdwarfs can be explained as the remnants of the mergers of helium-core white dwarfs with low-mass MS stars.

  11. Acoustic Measurements of a Large Civil Transport Main Landing Gear Model

    Science.gov (United States)

    Ravetta, Patricio A.; Khorrami, Mehdi R.; Burdisso, Ricardo A.; Wisda, David M.

    2016-01-01

    Microphone phased array acoustic measurements of a 26 percent-scale, Boeing 777-200 main landing gear model with and without noise reduction fairings installed were obtained in the anechoic configuration of the Virginia Tech Stability Tunnel. Data were acquired at Mach numbers of 0.12, 0.15, and 0.17 with the latter speed used as the nominal test condition. The fully and partially dressed gear with the truck angle set at 13 degrees toe-up landing configuration were the two most extensively tested configurations, serving as the baselines for comparison purposes. Acoustic measurements were also acquired for the same two baseline configurations with the truck angle set at 0 degrees. In addition, a previously tested noise reducing, toboggan-shaped fairing was re-evaluated extensively to address some of the lingering questions regarding the extent of acoustic benefit achievable with this device. The integrated spectra generated from the acoustic source maps reconfirm, in general terms, the previously reported noise reduction performance of the toboggan fairing as installed on an isolated gear. With the recent improvements to the Virginia Tech tunnel acoustic quality and microphone array capabilities, the present measurements provide an additional, higher quality database to the acoustic information available for this gear model.

  12. Large scale multi-zone creep finite element modelling of a main steam line branch intersection

    International Nuclear Information System (INIS)

    Payten, Warwick

    2006-01-01

    A number of papers detail the non-linear creep finite element analysis of branch pieces. Predominately these models have incorporated only a single material zone representing the parent material. Multi-zone models incorporating weld material and heat affected zones have primarily been two-dimensional analyses, in part due to the large number of elements required to adequately represent all of the zones. This paper describes a non-linear creep analysis of a main steam line branch intersection using creep properties to represent the parent metal, weld metal, and heat affected zone (HAZ), the stress redistribution over 100,000 h is examined. The results show that the redistribution leads to a complex stress state, particularly at the heat affected zone. Although, there is damage on the external surface of the branch piece as expected, the results indicate that the damage would be more widespread through extensive sections of the heat affected zone. This would appear to indicate that the time between damage indications on the surface using techniques such as replication and full thickness damage may be more limited then previously expected

  13. Acoustic Modeling and Analysis for the Space Shuttle Main Propulsion System Liner Crack Investigation

    Science.gov (United States)

    Casiano, Matthew J.; Zoladz, Tom F.

    2004-01-01

    Cracks were found on bellows flow liners in the liquid hydrogen feedlines of several space shuttle orbiters in 2002. An effort to characterize the fluid environment upstream of the space shuttle main engine low-pressure fuel pump was undertaken to help identify the cause of the cracks and also provide quantitative environments and loads of the region. Part of this effort was to determine the duct acoustics several inches upstream of the low-pressure fuel pump in the region of a bellows joint. A finite element model of the complicated geometry was made using three-dimensional fluid elements. The model was used to describe acoustics in the complex geometry and played an important role in the investigation. Acoustic mode shapes and natural frequencies of the liquid hydrogen in the duct and in the cavity behind the flow liner were determined. Forced response results were generated also by applying an edgetone-like forcing to the liner slots. Studies were conducted for state conditions and also conditions assuming two-phase entrapment in the backing cavity. Highly instrumented single-engine hot fire data confirms the presence of some of the predicted acoustic modes.

  14. Retrospective analysis of main and interaction effects in genetic association studies of human complex traits

    DEFF Research Database (Denmark)

    Tan, Qihua; Christiansen, Lene; Brasch-Andersen, Charlotte

    2007-01-01

    with that of the case-only model. RESULTS: Results from our simulation study indicate that our retrospective model exhibits high power in capturing even relatively small effect with reasonable sample sizes. Application of our method to data from an association study on the catalase -262C/T promoter polymorphism...

  15. Main effects of the Earth's rotation on the stationary states of ultra-cold neutrons

    International Nuclear Information System (INIS)

    Arminjon, Mayeul

    2008-01-01

    The relativistic corrections in the Hamiltonian for a particle in a uniformly rotating frame are discussed. They are shown to be negligible in the case of ultra-cold neutrons (UCN) in the Earth's gravity. The effect, on the energy levels of UCN, of the main term due to the Earth's rotation, i.e. the angular-momentum term, is calculated. The energy shift is found proportional to the energy level itself

  16. Main Memory

    OpenAIRE

    Boncz, Peter; Liu, Lei; Özsu, M.

    2008-01-01

    htmlabstractPrimary storage, presently known as main memory, is the largest memory directly accessible to the CPU in the prevalent Von Neumann model and stores both data and instructions (program code). The CPU continuously reads instructions stored there and executes them. It is also called Random Access Memory (RAM), to indicate that load/store instructions can access data at any location at the same cost, is usually implemented using DRAM chips, which are connected to the CPU and other per...

  17. Perceived local enforcement, personal beliefs,and underage drinking: an assessment of moderating and main effects.

    Science.gov (United States)

    Lipperman-Kreda, Sharon; Paschall, Mallie J; Grube, Joel W

    2009-01-01

    Strategies to enforce underage drinking laws are aimed at reducing youth access to alcohol from commercial and social sources and deterring its possession and use. However, the processes through which enforcement strategies may affect underage drinking are not well understood. This study examined three possible processes by which perceived enforcement of underage drinking laws and personal beliefs (perceived alcohol availability, perceived harm, and personal disapproval of alcohol use) may influence alcohol use among adolescents. Survey data were obtained from 20,747 adolescents (48.3% males) in 115 school districts who participated in the 2006 Oregon Healthy Teens survey. Linear regression analyses were conducted to examine possible interactive and main effects of perceived enforcement and personal beliefs on past-30-day alcohol use. Analyses were adjusted for clustering of observations within school districts and included student demographics and age of alcohol use initiation as covariates. Statistically significant interaction effects on past-30-day alcohol use were found for perceived police enforcement and the three personal beliefs variables, indicating weaker associations between personal beliefs and past-30-day alcohol use at higher levels of perceived enforcement. Main effects of perceived enforcement and personal beliefs variables were also observed in the presence of interaction effects. Evidence for a moderating effect of perceived local enforcement on the relationships between personal beliefs and drinking behaviors suggests that the combination of individually focused prevention programs and local enforcement of underage drinking laws may have the greatest impact on underage drinking.

  18. Study of an effective structural system with rational parameters based on main energy principles

    Directory of Open Access Journals (Sweden)

    Toporkova Katerina

    2017-01-01

    Full Text Available The effective architectural and construction system with rational parameters based on main energy principles applied to construction of buildings and constructions with a small-step and large-step frames, representing the metal frame of full factory production collected in spatial system on high-strength bolts and previously strained combined prestressed concrete slabs which formed without timbering is proposed in this paper. The main constructive and technological features of the proposed frame, which allows reducing construction period, increasing working efficiency, and reducing labor intensity by using factory-made materials, quick erection of all process elements through the use of highstrength bolts is considered. The advantages of this constructive system in comparison with alternative systems are shown. The basic concepts of "rational decisions" to the design, namely, the objective of the optimal management of the structure parameters, which can not only improve its basic performance indicators, but also, and most importantly, improve operational reliability, is presented.

  19. Effect of cortex mori on pharmacokinetic profiles of main isoflavonoids from pueraria lobata in rat plasma.

    Science.gov (United States)

    Xiao, Bingxin; Sun, Zengxian; Sun, Shu Yang; Dong, Jie; Li, Yanli; Gao, Shan; Pang, Jie; Chang, Qi

    2017-09-14

    Radix pueraria (the root of pueraria lobata (Wild.) Ohwi.), which contains a class of isoflavonoids as the main active components, as well as cortex mori (the root bark of Morus alba L), which contains abundant active alkaloids, have been employed for the treatment of diabetes in traditional Chinese medicine for centuries. In previous studies, pharmacodynamic synergistic reactions have been observed in compatible application of pueraria lobata isoflavonoids extracts (PLF) and cortex mori alkaloids extracts (CME) for inhibiting α-glycosidase activity. It has also been demonstrated that PLF can effectively slow down the absorption of active alkaloid from CME, so as to produce a higher effective concentration in small intestine for depressing the elevation of postprandial blood glucose through inhibiting α-glycosidase activity. In this study, the hypoglycemic effect of PLF, CME or CME-PLF mixture (the mixture of CME and PLF at a ratio of 1:6.3) was further evaluated through in vivo glucose tolerance studies. And the effect of CME on pharmacokinetic profiles of main isoflavonoids from PLF in rat plasma was investigated to further underlie compatibility mechanism of the two herbs. Four groups of rats received an oral dose of starch solution alone or simultaneously with drugs by gavage feeding. The blood samples were collected to determine glucose concentrations by glucose oxidase method. In addition, another two groups of rats were orally administered with PLF or CME-PLF. The plasma samples were collected and assayed using an LC/MS/MS method for comparatively pharmacokinetic studies of five main isoflavonoids. For starch loading, co-administration of CME-PLF resulted in more potent inhibition effects on glucose responses compared to those by CME or PLF in rat. The isoflavonoids from PLF were rapidly absorbed, presenting similarly low concentrations in plasma. When CME was added, the C max and AUC of all the five isoflavonoids were increased. A phenomenon of double

  20. The SFR-M∗ main sequence archetypal star-formation history and analytical models

    Science.gov (United States)

    Ciesla, L.; Elbaz, D.; Fensch, J.

    2017-12-01

    The star-formation history (SFH) of galaxies is a key assumption to derive their physical properties and can lead to strong biases. In this work, we derive the SFH of main sequence (MS) galaxies and show how the peak SFH of a galaxy depends on its seed mass at, for example, z = 5. This seed mass reflects the galaxy's underlying dark matter (DM) halo environment. We show that, following the MS, galaxies undergo a drastic slow down of their stellar mass growth after reaching the peak of their SFH. According to abundance matching, these masses correspond to hot and massive DM halos which state could result in less efficient gas inflows on the galaxies and thus could be the origin of limited stellar mass growth. As a result, we show that galaxies, still on the MS, can enter the passive region of the UVJ diagram while still forming stars. The best fit to the MS SFH is provided by a right skew peak function for which we provide parameters depending on the seed mass of the galaxy. The ability of the classical analytical SFHs to retrieve the star-formation rate (SFR) of galaxies from spectral energy distribution (SED) fitting is studied. Due to mathematical limitations, the exponentially declining and delayed SFH struggle to model high SFR, which starts to be problematic at z > 2. The exponentially rising and log-normal SFHs exhibit the opposite behavior with the ability to reach very high SFR, and thus model starburst galaxies, but they are not able to model low values such as those expected at low redshift for massive galaxies. By simulating galaxies SED from the MS SFH, we show that these four analytical forms recover the SFR of MS galaxies with an error dependent on the model and the redshift. They are, however, sensitive enough to probe small variations of SFR within the MS, with an error ranging from 5 to 40% depending on the SFH assumption and redshift; but all the four fail to recover the SFR of rapidly quenched galaxies. However, these SFHs lead to an artificial

  1. Main Alkaloids of Peganum harmala L. and Their Different Effects on Dicot and Monocot Crops

    Directory of Open Access Journals (Sweden)

    Chi Zhang

    2013-02-01

    Full Text Available Alkaloids with allelopathic activity are not as well-known as other allelochemicals. Our study revealed that total alkaloids from seeds of the medicinal plant Peganum harmala L. possessed significant growth inhibitory effect on four treated plants, with dicot plants (lettuce and amaranth being more sensitive than the tested monocot plants (wheat and ryegrass. Further investigation led to the isolation of harmaline and harmine as the main active ingredients in the total alkaloids of P. harmala seeds. Harmaline exerted potent inhibitory effects on seedling growth of treated plants, especially dicots, inhibiting root elongation of lettuce and amaranth by 31% and 47% at a very low concentration (5 µg/mL, whereas harmine exhibited much weaker non-selective inhibitory effect on the plants. Considering the high yield and poor utilization of P. harmala in China, we anticipate that this plant could be exploited as an alternative weed management tool in the future.

  2. Effect of increased fuel exploitation on the main characteristics of spent WWER 440 fuel

    International Nuclear Information System (INIS)

    Zib, A.

    2001-01-01

    The article deals with the effect of a higher fuel exploitation on the main characteristics (particularly radioactivity and decay heat power) of spent WWER 440 fuel. The main characteristics were calculated by using the Origen code. The study was implemented as a three-stage process. In the first stage, the radioactivity and residual thermal power time evolution values were calculated for the 'typical fuel', i. e. fuel assembly with initial enrichment of 3.6% U-235, 3 years in reactor, and burnup of 30 MWd/kg U. In the second stage, ceteris paribus radioactivity and thermal power analyses of sensitivity to changes in the fuel burnup, initial fuel enrichment, and time in reactor were carried out for the typical fuel assembly. In the third stage, the effect of changes in all three variables was investigated for fuel assemblies possessing parameters that approach those applied at the Dukovany NPP. The effect of a higher fuel exploitation on the interim fuel storage is also mentioned. (author)

  3. Modeling of Yield Estimation for The Main Crops in Iran Based on Mechanization Index (hp ha-1

    Directory of Open Access Journals (Sweden)

    K Abbasi

    2014-09-01

    Full Text Available Agricultural mechanization is a method for transiting from traditional agriculture towards industrial and sustainable one. Due to the limitation of natural resources and increasing population we need to have economical production of agricultural crops. For reaching this destination; agricultural mechanization has a remarkable role. So it is necessary to have an extensive view for mechanization, because with the help of mechanization the agricultural inputs such as seeds, fertilizer and even water and soil can effectively be managed for an economical and sustainable production. This study has been carried out in many provinces of Iran. The data of agricultural tractors and cereal combine harvesters were firstly gathered by means of questionnaire. The tractors were categorized in four power levels of less than 45, 45 to 80, 80 to 110, and more than 110 hp. In addition, it was also carried out for cereal combine harvesters; it was in three power levels, i.e. between 100 to 110, 110 to 155 and 155 to 210 horse-power in 3 ages, i.e. less than 13, between 13 to 20, and more than 20 years. Information regarding to cultivation areas, production volume, and yield of main crops gathered from statistics of Ministry of Jihad-e-Agriculture. Then agriculture mechanization level index (hp ha-1 in each province was calculated. Four main crops including irrigated and rain-fed wheat and irrigated and rain-fed barley, which met the required criteria to be used in the model, were statistically analyzed. Correlation analysis was carried out in order to get an effective model between yield of the four main crops in Iran and agriculture mechanization level index. Pearson correlation index showed that there is a direct and significant correlation between these variables. Subsequently, outliers were identified in order to get a model with necessary efficiency to predict the yield through mechanization level index, by scatter diagram and estimating regression lines in 1

  4. Aquatic photochemistry of sulfamethazine: multivariate effects of main water constituents and mechanisms.

    Science.gov (United States)

    Li, Yingjie; Liu, Xiangliang; Zhang, Biaojun; Zhao, Qun; Ning, Ping; Tian, Senlin

    2018-03-01

    The ubiquity of sulfonamides (SAs) in natural waters requires insight into their environmental fate for ecological risk assessment. Extensive studies focused on the effect of univariate water constituents on the photochemical fate of SAs, yet the multivariate effects of water constituents in environmentally relevant concentrations on SA photodegradation are poorly understood. Here, response surface methodology was employed to explore the integrative effects of main water constituents (dissolved organic matter (DOM), NO 3 - , HCO 3 - , Cu 2+ ) on the photodegradation of a representative SA (sulfamethazine). Results showed that besides single factors, interaction of factors also significantly impacted the photodegradation. Radical scavenging experiments indicated that triplet-excited DOM ( 3 DOM*) was responsible for the enhancing effect of DOM on the photodegradation. Additionally, DOM may also quench the 3 DOM*-mediated oxidation intermediate of sulfamethazine causing the inhibiting effect of DOM-DOM interaction. We also found that HCO 3 - was oxidized by triplet-excited sulfamethazine producing CO 3 ˙ - , and the high reactivity of CO 3 ˙ - with sulfamethazine (second-order rate constant 2.2 × 10 8 M -1 s -1 ) determined by laser flash photolysis revealed the enhancing photodegradation mechanism of HCO 3 - . This study is among the first attempts to probe the photodegradation of SAs considering the integrative effects of water constituents, which is important in accurate ecological risk assessment of organic pollutants in the aquatic environment.

  5. The permeability characteristics and interaction of main components from Si-Ni-San in a MDCK epithelial cell monolayer model.

    Science.gov (United States)

    Chen, Ruonan; Shen, Chenlin; Xu, Qingqing; Liu, Yaru; Li, Bo; Huang, Cheng; Ma, Taotao; Meng, Xiaoming; Wu, Maomao; Li, Jun

    2017-07-26

    1. Si-Ni-San (SNS) possesses extensive therapeutic effects, however, the extent to which main components are absorbed and the mechanisms involved are controversial. 2. In this study, MDCK cell model was used to determine the permeability characteristics and interaction between the major components of Si-Ni-San, including saikosaponin a, paeoniflorin, naringin and glycyrrhizic acid. 3. The transport of the major components was concentration-dependent in both directions. Moreover, the transport of paeoniflorin, naringin and glycyrrhizic acid was significantly reduced at 4°C or in the presence of NaN3. Additionally, the efflux of paeoniflorin and naringin were apparently reduced in the presence of P-gp inhibitor verapamil. The transport of glycyrrhizic acid was clearly inhibited by the inhibitors of MRP2, indicating that MRP2 may be involved in the transport of glycyrrhizic acid. However, the results indicated that saikosaponin a was absorbed mainly by passive diffusion. Furthermore, the combined incubation of four major components had a powerful sorbefacient effect than a single drug used alone which may be regulated by tight junctions. 4. Taken together, our study provides useful information for pharmacological applications of Si-Ni-San and offers new insights into this ancient decoction for further researches, especially in drug synergism.

  6. Modeling of behaviour of main type personnel in Kozloduy NPP during different operational conditions

    International Nuclear Information System (INIS)

    Hristova, R.; Kalchev, B.

    2000-01-01

    The subject of this article is the personnel behavior and initiating events modeling, based on the operational experience in the NPP 'Kozloduy' initiating events reports. The development of models on qualitative information is much more difficult comparing the quantitative modeling. The modelling process is based on the artificial intelligence theory and methods including knowledge base and inference machine in the frame of logical models and semantic networks. (author)

  7. Internet advertising effectiveness measurement model

    OpenAIRE

    Marcinkevičiūtė, Milda

    2007-01-01

    The research object of the master thesis is internet advertising effectiveness measurement. The goal of the work is after making theoretical studies of internet advertising effectiveness measurement (theoretical articles, practical researches and cetera), formulate the conceptual IAEM model and examine it empirically. The main tasks of the work are: to analyze internet advertising, it’s features, purposes, spread formats, functions, advantages and disadvantages; present the effectiveness of i...

  8. Gastrointestinal effects of Nigella sativa and its main constituent, thymoquinone: a review

    Directory of Open Access Journals (Sweden)

    Farzaneh Shakeri

    2016-01-01

    Full Text Available Gastrointestinal (GI diseases affect a large number of people all over the world. Uncontrolled acid secretion and occurrence of gastric ulcers are common disorders of GI tract which pose serious problems to human health. Many synthetic drugs have been used to treat GI disorders but a definite cure has not been discovered so far and the available medications cause several side effects. Nigella sativa (N. sativa (Ranunculacea has several therapeutic effects which are attributed to its constituents like nigellicine, nigellidine, thymoquinone, dithymoquinone, thymol and carvacrol. Several beneficial pharmacological properties of this plant such as anti-oxidant, anti-bacterial, anti-histaminic, anti-hypertensive, hypoglycemic, anti-fungal, anti-inflammatory, anti-cancer and immunomodulatory effects were reported and different therapeutic properties such as reliving bronchial asthma, jaundice, hydrophobia, paralysis, conjunctivitis, piles, skin diseases, anorexia, headache, dysentery, infections, obesity, back pain, hypertension and gastrointestinal problems, have been described for the seeds of N. sativa and its oil. The present review provides a detailed summery of scientific researches regarding gastrointestinal effect of N. sativa and its main constituent, thymoquinone.

  9. Cost-effectiveness of the stream-gaging program in Maine; a prototype for nationwide implementation

    Science.gov (United States)

    Fontaine, Richard A.; Moss, M.E.; Smath, J.A.; Thomas, W.O.

    1984-01-01

    This report documents the results of a cost-effectiveness study of the stream-gaging program in Maine. Data uses and funding sources were identified for the 51 continuous stream gages currently being operated in Maine with a budget of $211,000. Three stream gages were identified as producing data no longer sufficiently needed to warrant continuing their operation. Operation of these stations should be discontinued. Data collected at three other stations were identified as having uses specific only to short-term studies; it is recommended that these stations be discontinued at the end of the data-collection phases of the studies. The remaining 45 stations should be maintained in the program for the foreseeable future. The current policy for operation of the 45-station program would require a budget of $180,300 per year. The average standard error of estimation of streamflow records is 17.7 percent. It was shown that this overall level of accuracy at the 45 sites could be maintained with a budget of approximately $170,000 if resources were redistributed among the gages. A minimum budget of $155,000 is required to operate the 45-gage program; a smaller budget would not permit proper service and maintenance of the gages and recorders. At the minimum budget, the average standard error is 25.1 percent. The maximum budget analyzed was $350,000, which resulted in an average standard error of 8.7 percent. Large parts of Maine's interior were identified as having sparse streamflow data. It was determined that this sparsity be remedied as funds become available.

  10. Percutaneous Coronary Intervention of Left Main Disease: Pre- and Post-EXCEL (Evaluation of XIENCE Everolimus Eluting Stent Versus Coronary Artery Bypass Surgery for Effectiveness of Left Main Revascularization) and NOBLE (Nordic-Baltic-British Left Main Revascularization Study) Era.

    Science.gov (United States)

    Park, Duk-Woo; Park, Seung-Jung

    2017-06-01

    For nearly half a century, coronary artery bypass grafting has been the standard treatment for patients with obstructive left main coronary artery (LMCA) disease. However, there has been considerable evolution in the field of percutaneous coronary intervention, and especially, percutaneous coronary intervention for LMCA disease has been rapidly expanded with adoption of drug-eluting stents. Some, but not all randomized trials, have shown that percutaneous coronary intervention with drug-eluting stents might be a suitable alternative for selected patients with LMCA disease instead of bypass surgery. However, none of previous trials involving early-generation drug-eluting stents was sufficiently powered and comparative trials using contemporary drug-eluting stents were limited. Recently, primary results of 2 new trials of EXCEL (Evaluation of XIENCE Everolimus Eluting Stent Versus Coronary Artery Bypass Surgery for Effectiveness of Left Main Revascularization) and NOBLE (Nordic-Baltic-British Left Main Revascularization Study) were reported. However, these trials showed conflicting results, which might pose uncertainty on the optimal revascularization strategy for LMCA disease. In this article, with the incorporation of a key review on evolution of LMCA treatment, we summarize the similarity or disparity of the EXCEL and NOBLE trials, focus on how they relate to previous trials in the field, and finally speculate on how the treatment strategy may be changed or recommended for LMCA treatment. © 2017 American Heart Association, Inc.

  11. Effects of Chlorophenoxy Herbicides and Their Main Transformation Products on DNA Damage and Acetylcholinesterase Activity

    Directory of Open Access Journals (Sweden)

    Sofia Benfeito

    2014-01-01

    Full Text Available Persistent pesticide transformation products (TPs are increasingly being detected among different environmental compartments, including groundwater and surface water. However, there is no sufficient experimental data on their toxicological potential to assess the risk associated with TPs, even if their occurrence is known. In this study, the interaction of chlorophenoxy herbicides (MCPA, mecoprop, 2,4-D and dichlorprop and their main transformation products with calf thymus DNA by UV-visible absorption spectroscopy has been assessed. Additionally, the toxicity of the chlorophenoxy herbicides and TPs was also assessed evaluating the inhibition of acetylcholinesterase activity. On the basis of the results found, it seems that AChE is not the main target of chlorophenoxy herbicides and their TPs. However, the results found showed that the transformation products displayed a higher inhibitory activity when compared with the parent herbicides. The results obtained in the DNA interaction studies showed, in general, a slight effect on the stability of the double helix. However, the data found for 4-chloro-2-methyl-6-nitrophenol suggest that this transformation product can interact with DNA through a noncovalent mode.

  12. Modeling of Camembert-type cheese mass loss in a ripening chamber: main biological and physical phenomena.

    Science.gov (United States)

    Hélias, A; Mirade, P-S; Corrieu, G

    2007-11-01

    A model of the mass loss of Camembert-type cheese was established with data obtained from 2 experimental ripening trials carried out in 2 pilot ripening chambers. During these experiments, a cheese was continuously weighed and the relative humidity, temperature, oxygen, and carbon dioxide concentrations in the ripening chamber were recorded online. The aim was to establish a simple but accurate model that would predict cheese mass changes according to available online measurements. The main hypotheses were that 1) the cheese water activity was constant during ripening, 2) the respiratory activity of the microflora played a major role by inducing heat production, combined with important water evaporation, 3) the temperature gradient existing inside the cheese was negligible, and the limiting phenomenon was the convective transfer. The water activity and the specific heat of the cheeses were assessed by offline measurements. The others parameters in the model were obtained from the literature. This dynamic model was built with 2 state variables: the cheese mass and the surface temperature of the cheese. In this way, only the heat transfer coefficient had to be fitted, and it was strongly determined by the airflow characteristics close to the cheeses. Model efficiency was illustrated by comparing the estimated and measured mass and the mass loss rate for the 2 studied runs; the relative errors were less than 1.9 and 3.2% for the mass loss and the mass loss rate, respectively. The dynamic effects of special events, such as room defrosting or changes in chamber relative humidity, were well described by the model, especially in terms of kinetics (mass loss rates).

  13. Effect of Generalized Uncertainty Principle on Main-Sequence Stars and White Dwarfs

    Directory of Open Access Journals (Sweden)

    Mohamed Moussa

    2015-01-01

    Full Text Available This paper addresses the effect of generalized uncertainty principle, emerged from different approaches of quantum gravity within Planck scale, on thermodynamic properties of photon, nonrelativistic ideal gases, and degenerate fermions. A modification in pressure, particle number, and energy density are calculated. Astrophysical objects such as main-sequence stars and white dwarfs are examined and discussed as an application. A modification in Lane-Emden equation due to a change in a polytropic relation caused by the presence of quantum gravity is investigated. The applicable range of quantum gravity parameters is estimated. The bounds in the perturbed parameters are relatively large but they may be considered reasonable values in the astrophysical regime.

  14. Sand and gravel mining: effects on ground water resources in Hancock county, Maine, USA

    Science.gov (United States)

    Peckenham, John M.; Thornton, Teresa; Whalen, Bill

    2009-01-01

    Based on this preliminary study, existing sand and gravel mining regulations (in Maine, USA) can be inferred to provide some protection to water resources. Sand and gravel deposits are important natural resources that have dual uses: mining for construction material and pumping for drinking water. How the mining of sand and gravel affects aquifers and change aquifer vulnerability to contamination is not well documented. Mining regulations vary greatly by state and local jurisdiction. This study test metrics to measure the effectiveness of mining regulations. The sand and gravel aquifer system studied is covered with former and active gravel pits to nearly 25% of its areal extent. Data from homeowner interviews and field measurements found scant evidence of changes in water quantity. Water quality analyses collected from springs, streams, ponds and wells indicate that the aquifer was vulnerable to contamination by chloride and nitrate. However, water quality changes can not be related directly to mining activities.

  15. Ab initio effective core potentials for molecular calculations. Potentials for main group elements Na to Bi

    International Nuclear Information System (INIS)

    Wadt, W.R.; Hay, P.J.

    1985-01-01

    A consistent set of ab initio effective core potentials (ECP) has been generated for the main group elements from Na to Bi using the procedure originally developed by Kahn. The ECP's are derived from all-electron numerical Hartree--Fock atomic wave functions and fit to analytical representations for use in molecular calculations. For Rb to Bi the ECP's are generated from the relativistic Hartree--Fock atomic wave functions of Cowan which incorporate the Darwin and mass--velocity terms. Energy-optimized valence basis sets of (3s3p) primitive Gaussians are presented for use with the ECP's. Comparisons between all-electron and valence-electron ECP calculations are presented for NaF, NaCl, Cl 2 , Cl 2 - , Br 2 , Br 2 - , and Xe 2 + . The results show that the average errors introduced by the ECP's are generally only a few percent

  16. Effects of main actor, outcome and affect on biased braking speed judgments

    Directory of Open Access Journals (Sweden)

    Ola Svenson

    2012-05-01

    Full Text Available Subjects who judged speed in a driving scenario overestimated how fast they could decelerate when speeding compared to when keeping within the speed limit (Svenson, 2009. The purpose of the present studies were to replicate studies conducted in Europe with subjects in the U.S., to study the influence of speed unit (kph vs. mph, affective reactions to outcome (collision and identity of main actor (driver on braking speed judgments. The results replicated the European findings and the outcome affective factor (passing a line/killing a child and the actor factor (subject/driver in general had significant effects on judgments of braking speed. The results were related to psychological theory and applied implications were discussed.

  17. Fluid elastic instability analysis of 1/6th experimental model of PFBR main vessel cooling circuit

    International Nuclear Information System (INIS)

    Jalaldeen, S.; Ravi, R.; Chellapandi, P.; Bhoje, S.B.

    1993-01-01

    In reactor assembly of Prototype Fast Breeder Reactor (PFBR), the main vessel (MV) temperature is kept below creep range i.e. less than 427 deg C by way of diverting a small fraction of core flow from the cold pool and sent through the passage between main vessel and an outer cylindrical baffle to cool the vessel. The sodium coning from this, is collected by another inner baffle and then returned to cold pool again. This system is termed as MV cooling circuit. The outer and inner baffles form feeding and restitution collectors respectively. The sodium from the feeding collector flows over the outer baffle and falls through a height of about 0.5 m before impacting on the free surface of sodium in the restitution collector. The fall of sodium may become a source of vibration of the baffles. Such vibrations have been already noted in case of SPX-I during its commissioning stage. For PFBR, the theoretical analysis was done to assess the fluid-elastic instability risks and stability charts were obtained. By this, it was concluded that the operating point (flow rate and fall height) lies within the stable zone. In order to confirm the above analysis results, a series of experiments were proposed. One preliminary experiment on 1/16 th model of MV cooling circuit has been completed. This model has also been analysed theoretically for the fluid- elastic instability, the theoretical analysis involves 2 stage computations. In the first stage, free vibration analysis with fluid structure interaction (FSI) effect for experimental model has been done using INCA (CASTEM 1985) code and all the mode shapes including sloshing are extracted. In the second stage the instability analysis is performed with the free vibration results from INCA. For the instability computations, a code WEIR has been written based on Aita's instability criteria [Aita.S. 1986

  18. Effectiveness of experimental system in children’s mastering of main manual motor skills

    Directory of Open Access Journals (Sweden)

    L. L. Galamandjuk

    2015-07-01

    Full Text Available Purpose: determine effectiveness of simulated system of pre-school age children motor functioning’s preventive development for mastering of main movements for manual skills. Material: in the research five years’ children (control group n=150 and experimental group n=120 participated. Results: it was determined that transition from uncomfortable to comfortable for a child conditions of exercises’ fulfillment facilitates quicker formation of required motor program. It is connected with the fact that, independent on orientation of manual motor asymmetry progressing of semi-spheres’ interaction takes place. This interaction is an important condition of increasing of child functioning’s effectiveness in different aspects. Achievement of such result was also facilitated by physical exercises, which children practiced at home. Functioning of physical culture instructor and kindergarten teachers was also important: they formed parents’ conscious position concerning importance of such trainings; recommended effective means and methods. Conclusions: application of the offered system ensures much better result than traditional approach to this problem. It is one of keys to prevention of negative tendencies in development of pre-school age children.

  19. A review of Neuropharmacology Effects of Nigella sativa and Its Main Component, Thymoquinone.

    Science.gov (United States)

    Javidi, Soheila; Razavi, Bibi Marjan; Hosseinzadeh, Hossein

    2016-08-01

    Neuropharmacology is the scientific study of drug effect on nervous system. In the last few years, different natural plants and their active constituents have been used in neurological therapy. The availability, lower price, and less toxic effects of herbal medicines compared with synthetic agents make them as simple and excellent choice in the treatment of nervous diseases. Nigella sativa, which belongs to the botanical family of Ranunculaceae, is a widely used medicinal plant all over the world. In traditional and modern medicines several beneficial properties have been attributed to N. sativa and its main component, thymoquinone (TQ). In this review, various studies in scientific databases regarding the neuropharmacological aspects of N. sativa and TQ have been introduced. Results of these studies showed that N. sativa and TQ have several properties including anticonvulsant, antidepressant, anxiolytic, anti-ischemic, analgesic, antipsychotic, and memory enhancer. Furthermore, its protective effects against neurodegenerative diseases such as Alzheimer, Parkinson and multiple sclerosis have been discussed. Although there are many studies indicating the beneficial actions of this plant in nervous system, the number of research projects relating to the human reports is rare. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  20. EVOLUTION OF THE MAIN MODELS OF INTEGRATED MARKETING COMMUNICATIONS WHO HAVE THE ROLE TO INFLUENCE CONSUMER BUYING BEHAVIOR

    Directory of Open Access Journals (Sweden)

    OANCEA OLIMPIA ELENA MIHAELA

    2015-03-01

    Full Text Available The models of integrated marketing communication have become today a very useful tool, that can provide companies a sustainable competitive advantage. The integrated marketing communication identifies with today's market dynamics and learn organizations how easy it can be to prosper in an environment where there are produced changes in an alarming way. In an economy with a strong competition character, organizations must capitalize integrated marketing communication in a way more efficiently, for to ensure the creation and maintenance of longterm relationships with current and potential customers. A product or a brand exist in the consumer's mind there not only because of experience with it, but also due to the medium and long term effects on that a message built on base the wishes, expectations or consumer preferences is transmitted simultaneously through as many tools of communication. Building and managing relationships with consumers can have a direct and positive effect on efficiency of the results of communication of a company. Changes in the business environment, along with technological innovation, increasing consumer sophistication and changes in marketing communications practices, have led organizations to seek to improve relationships with their consumers, and to strive to deliver consistent messages to all stakeholders - consumers, employees, company partners, the state, local governments, suppliers - across a wide range of integrated marketing communications channels.Therefore, the purpose of this article is to identify and analyze the main models of integrated marketing communication that can influence the consumer behaviour.

  1. Monte Carlo modeling and analyses of YALINA-booster subcritical assembly part 1: analytical models and main neutronics parameters

    International Nuclear Information System (INIS)

    Talamo, A.; Gohar, M. Y. A.; Nuclear Engineering Division

    2008-01-01

    This study was carried out to model and analyze the YALINA-Booster facility, of the Joint Institute for Power and Nuclear Research of Belarus, with the long term objective of advancing the utilization of accelerator driven systems for the incineration of nuclear waste. The YALINA-Booster facility is a subcritical assembly, driven by an external neutron source, which has been constructed to study the neutron physics and to develop and refine methodologies to control the operation of accelerator driven systems. The external neutron source consists of Californium-252 spontaneous fission neutrons, 2.45 MeV neutrons from Deuterium-Deuterium reactions, or 14.1 MeV neutrons from Deuterium-Tritium reactions. In the latter two cases a deuteron beam is used to generate the neutrons. This study is a part of the collaborative activity between Argonne National Laboratory (ANL) of USA and the Joint Institute for Power and Nuclear Research of Belarus. In addition, the International Atomic Energy Agency (IAEA) has a coordinated research project benchmarking and comparing the results of different numerical codes with the experimental data available from the YALINA-Booster facility and ANL has a leading role coordinating the IAEA activity. The YALINA-Booster facility has been modeled according to the benchmark specifications defined for the IAEA activity without any geometrical homogenization using the Monte Carlo codes MONK and MCNP/MCNPX/MCB. The MONK model perfectly matches the MCNP one. The computational analyses have been extended through the MCB code, which is an extension of the MCNP code with burnup capability because of its additional feature for analyzing source driven multiplying assemblies. The main neutronics parameters of the YALINA-Booster facility were calculated using these computer codes with different nuclear data libraries based on ENDF/B-VI-0, -6, JEF-2.2, and JEF-3.1

  2. Monte Carlo modeling and analyses of YALINA-booster subcritical assembly part 1: analytical models and main neutronics parameters.

    Energy Technology Data Exchange (ETDEWEB)

    Talamo, A.; Gohar, M. Y. A.; Nuclear Engineering Division

    2008-09-11

    This study was carried out to model and analyze the YALINA-Booster facility, of the Joint Institute for Power and Nuclear Research of Belarus, with the long term objective of advancing the utilization of accelerator driven systems for the incineration of nuclear waste. The YALINA-Booster facility is a subcritical assembly, driven by an external neutron source, which has been constructed to study the neutron physics and to develop and refine methodologies to control the operation of accelerator driven systems. The external neutron source consists of Californium-252 spontaneous fission neutrons, 2.45 MeV neutrons from Deuterium-Deuterium reactions, or 14.1 MeV neutrons from Deuterium-Tritium reactions. In the latter two cases a deuteron beam is used to generate the neutrons. This study is a part of the collaborative activity between Argonne National Laboratory (ANL) of USA and the Joint Institute for Power and Nuclear Research of Belarus. In addition, the International Atomic Energy Agency (IAEA) has a coordinated research project benchmarking and comparing the results of different numerical codes with the experimental data available from the YALINA-Booster facility and ANL has a leading role coordinating the IAEA activity. The YALINA-Booster facility has been modeled according to the benchmark specifications defined for the IAEA activity without any geometrical homogenization using the Monte Carlo codes MONK and MCNP/MCNPX/MCB. The MONK model perfectly matches the MCNP one. The computational analyses have been extended through the MCB code, which is an extension of the MCNP code with burnup capability because of its additional feature for analyzing source driven multiplying assemblies. The main neutronics parameters of the YALINA-Booster facility were calculated using these computer codes with different nuclear data libraries based on ENDF/B-VI-0, -6, JEF-2.2, and JEF-3.1.

  3. Overview of the Main Theories on the Economic Effects of Public Indebtedness

    Directory of Open Access Journals (Sweden)

    Irina Bilan

    2016-05-01

    Full Text Available The paper briefly reviews the main theories formulated over time on the economic effects of public indebtedness, with the aim to highlight their common and divergent points, the arguments they rely upon, as well as their relevance, given the current economic environment. Three major views are considered, namely the classical one, the Keynesian one and the view of neoliberal economists (monetarist economists and representatives of the school of rational expectations. The comparative approach of the different views allowed us to shape some criteria of decision which may prove useful for public policymakers in formulating public debt policies conducive to economic growth: public indebtedness should not become common practice but be reserved for those situations in which the economy is confronted with unusual phenomena, such as economic downturns; borrowed resources should be used especially on those destinations which create added value in the economy, such as public investment; public debt should not accumulate at a fast pace and should be kept within reasonable limits, to avoid possible side effects on economic growth.

  4. Cost Effectiveness of ASHRAE Standard 90.1-2013 for the State of Maine

    Energy Technology Data Exchange (ETDEWEB)

    Hart, Philip R. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Athalye, Rahul A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Xie, YuLong [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Zhuge, Jing Wei [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Halverson, Mark A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Loper, Susan A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Rosenberg, Michael I. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Richman, Eric E. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2015-12-01

    Moving to the ASHRAE Standard 90.1-2013 (ASHRAE 2013) edition from Standard 90.1-2010 (ASHRAE 2010) is cost-effective for the State of Maine. The table below shows the state-wide economic impact of upgrading to Standard 90.1-2013 in terms of the annual energy cost savings in dollars per square foot, additional construction cost per square foot required by the upgrade, and life-cycle cost (LCC) per square foot. These results are weighted averages for all building types in all climate zones in the state, based on weightings shown in Table 4. The methodology used for this analysis is consistent with the methodology used in the national cost-effectiveness analysis. Additional results and details on the methodology are presented in the following sections. The report provides analysis of two LCC scenarios: Scenario 1, representing publicly-owned buildings, considers initial costs, energy costs, maintenance costs, and replacement costs—without borrowing or taxes. Scenario 2, representing privately-owned buildings, adds borrowing costs and tax impacts.

  5. Models of cognitive behavior in nuclear power plant personnel. A feasibility study: main report. Volume 2

    International Nuclear Information System (INIS)

    Woods, D.D.; Roth, E.M.; Hanes, L.F.

    1986-07-01

    This report contains the results of a feasibility study to determine if the current state of models human cognitive activities can serve as the basis for improved techniques for predicting human error in nuclear power plants emergency operations. Based on the answer to this questions, two subsequent phases of research are planned. Phase II is to develop a model of cognitive activities, and Phase III is to test the model. The feasibility study included an analysis of the cognitive activities that occur in emergency operations and an assessment of the modeling concepts/tools available to capture these cognitive activities. The results indicated that a symbolic processing (or artificial intelligence) model of cognitive activities in nuclear power plants is both desirable and feasible. This cognitive model can be built upon the computational framework provided by an existing artificial intelligence system for medical problem solving called Caduceus. The resulting cognitive model will increase the capability to capture the human contribution to risk in probabilistic risk assessments studies. Volume I summarizes the major findings and conclusions of the study. Volume II provides a complete description of the methods and results, including a synthesis of the cognitive activities that occur during emergency operations, and a literature review on cognitive modeling relevant to nuclear power plants. 112 refs., 10 figs

  6. Demographic Characteristics of a Maine Woodcock Population and Effects of Habitat Management

    Science.gov (United States)

    Dwyer, T.J.; Sepik, G.F.; Derleth, E.L.; McAuley, D.G.

    1988-01-01

    A population of American woodcock (Scolopax minor) was studied on a 3,401-ha area of the Moosehorn National Wildlife Refuge in northeastern Maine from 1976 through 1985. During 1976-83, from 4 to 64 clearcuts were created each year, opening up large contiguous blocks of forest. A combination of mist nets, ground traps, nightlighting techniques, and trained dogs were used to capture and band 1,884 birds during the first 5 years. Capture and recapture data (totaling 3,009 observations) were used with both demographically closed and open population models to estimate population size and, for open population models, summer survival. Flying young, especially young males, represented the greatest proportion of all captures; analysis showed that young males were more prone to capture than young females. Male courtship began about 24 March each year, usually when there was still snow in wooded areas. Males ~2 years old dominated singing grounds during April each year, but this situation changed and first-year males dominated singing grounds in May. Singing males shifted from older established singing grounds to new clearcuts soon after we initiated forest management. Many males were subdominant at singing grounds despite an abundance of unoccupied openings. Three hundred adult females were captured and, except for 1978, the majority were ~2 years old. The year in which female homing rate was lowest(1979) was preceded by the year with the largest number of l-year-old brood female captures and a summer drought. Summer survival of young was lowest in 1978 and was attributed to summer drought. The year 1979 had an abnormally cool and wet spring, and was the poorest for production of young. Capture ratios of young-to-adult females obtained by nightlighting could be used to predict production on our study area. Closed population model estimates did not seem to fit either young or adult data sets well. Instead, a partially open capture-recapture model that allowed death but no

  7. Hospitality Invites Sociability, Which Builds Cohesion: a Model for the Role of Main Streets in Population Mental Health.

    Science.gov (United States)

    Izenberg, Jacob M; Fullilove, Mindy Thompson

    2016-04-01

    The aim of this study was to investigate the contribution of main streets to community social cohesion, a factor important to health. Prior work suggests that casual contact in public space, which we call "sociability," facilitates more sustained social bonds in the community. We appropriate the term "hospitality" to describe a main street's propensity to support a density of such social interactions. Hospitality is a result of the integrity and complex contents of the main street and surrounding area. We examine this using a typology we term "box-circle-line" to represent the streetscape (the box), the local neighborhood (the circle), and the relationship to the regional network of streets (the line). Through field visits to 50 main streets in New Jersey and elsewhere, and a systematic qualitative investigation of main streets in a densely interconnected urban region (Essex County, New Jersey), we observed significant variation in main street hospitality, which generally correlated closely with sociability. Physical elements such as street wall, neighborhood elements such as connectivity, inter-community elements such as access and perceived welcome, and socio-political elements such as investment and racial discrimination were identified as relevant to main street hospitality. We describe the box-circle-line as a theoretical model for main street hospitality that links these various factors and provides a viable framework for further research into main street hospitality, particularly with regard to geographic health disparities.

  8. Triggering the Activation of Main-belt Comets: The Effect of Porosity

    Science.gov (United States)

    Haghighipour, N.; Maindl, T. I.; Schäfer, C. M.; Wandel, O. J.

    2018-03-01

    It has been suggested that the comet-like activity of Main-belt comets (MBCs) is due to the sublimation of sub-surface water-ice that is exposed when these objects are impacted by meter-sized bodies. We recently examined this scenario and showed that such impacts can, in fact, excavate ice and present a plausible mechanism for triggering the activation of MBCs. However, because the purpose of that study was to prove the concept and identify the most viable ice-longevity model, the porosity of the object and the loss of ice due to the heat of impact were ignored. In this paper, we extend our impact simulations to porous materials and account for the loss of ice due to an impact. We show that for a porous MBC, impact craters are deeper, reaching to ∼15 m, implying that if the activation of MBCs is due to the sublimation of sub-surface ice, this ice has to be within the top 15 m of the object. Results also indicate that the loss of ice due to the heat of impact is negligible, and the re-accretion of ejected ice is small. The latter suggests that the activities of current MBCs are most probably from multiple impact sites. Our study also indicates that for sublimation from multiple sites to account for the observed activity of the currently known MBCs, the water content of MBCs (and their parent asteroids) needs to be larger than the values traditionally considered in models of terrestrial planet formation.

  9. A study on discrete event dynamic model for nuclear operations of main feed water pump

    International Nuclear Information System (INIS)

    Bae, J. C.; Choi, J. I.

    2000-01-01

    A major objective of the study is to propose a supervisory control algorithm based on the discrete event dynamic system (DEDS) model and apply it to the automation of nuclear operations. The study is motivated by the suitability of the DEDS model for simulation of man-made control action and the potential of the DEDS based supervisory control algorithm for enhanced licensibility, when implemented in nuclear plants, through design transparency due to strong analytic backgrounds. The DEDS model can analytically show the robust stability of the proposed supervisory controller providing design transparency for enhanced licensibility when implemented in nuclear operations

  10. Molecules and Models The molecular structures of main group element compounds

    CERN Document Server

    Haaland, Arne

    2008-01-01

    This book provides a systematic description of the molecular structures and bonding in simple compounds of the main group elements with particular emphasis on bond distances, bond energies and coordination geometries. The description includes the structures of hydrogen, halogen and methyl derivatives of the elements in each group, some of these molecules are ionic, some polar covalent. The survey of molecules whose structures conform to well-established trends is followed byrepresentative examples of molecules that do not conform. We also describe electron donor-acceptor and hydrogen bonded co

  11. Potential effects of climate change on the distribution range of the main silicate sinker of the Southern Ocean.

    Science.gov (United States)

    Pinkernell, Stefan; Beszteri, Bánk

    2014-08-01

    Fragilariopsis kerguelensis, a dominant diatom species throughout the Antarctic Circumpolar Current, is coined to be one of the main drivers of the biological silicate pump. Here, we study the distribution of this important species and expected consequences of climate change upon it, using correlative species distribution modeling and publicly available presence-only data. As experience with SDM is scarce for marine phytoplankton, this also serves as a pilot study for this organism group. We used the maximum entropy method to calculate distribution models for the diatom F. kerguelensis based on yearly and monthly environmental data (sea surface temperature, salinity, nitrate and silicate concentrations). Observation data were harvested from GBIF and the Global Diatom Database, and for further analyses also from the Hustedt Diatom Collection (BRM). The models were projected on current yearly and seasonal environmental data to study current distribution and its seasonality. Furthermore, we projected the seasonal model on future environmental data obtained from climate models for the year 2100. Projected on current yearly averaged environmental data, all models showed similar distribution patterns for F. kerguelensis. The monthly model showed seasonality, for example, a shift of the southern distribution boundary toward the north in the winter. Projections on future scenarios resulted in a moderately to negligibly shrinking distribution area and a change in seasonality. We found a substantial bias in the publicly available observation datasets, which could be reduced by additional observation records we obtained from the Hustedt Diatom Collection. Present-day distribution patterns inferred from the models coincided well with background knowledge and previous reports about F. kerguelensis distribution, showing that maximum entropy-based distribution models are suitable to map distribution patterns for oceanic planktonic organisms. Our scenario projections indicate

  12. Bar Harbor, Maine 1/3 Arc-second MWH Coastal Digital Elevation Model

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA's National Geophysical Data Center (NGDC) is building high-resolution digital elevation models (DEMs) for select U.S. coastal regions. These integrated...

  13. Bar Harbor, Maine 1/3 Arc-second NAVD 88 Coastal Digital Elevation Model

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA's National Geophysical Data Center (NGDC) is building high-resolution digital elevation models (DEMs) for select U.S. coastal regions. These integrated...

  14. The Study of Main and Interactive Effects of Attachment Dimension and Basic Personality Characteristics in Borderline Traits

    Directory of Open Access Journals (Sweden)

    Ali Mohammadzadeh

    2012-10-01

    Full Text Available Background: There are models of the development of personality disorders which include individual differences in attachment relationships as causal factors contributed in explanation of these phenomena. The dimensional view of personality disorders represents these conditions as extreme variants of normal personality continua. This study investigated main and interactional effects of attachment styles and personality traits in relation to borderline characteristics. Materials and Methods: The current study was conducted in expo fact context. Randomly selected 603 participants (134 male  469 female from Tabriz Payam-e-Noor, Tarbait Moallem of Azarbaijan and Sarab Payam-e-Noor university students took part in this research. Participants answered to Borderline Personality Inventory (BPI, Eysenck Personality Questionnaire Revised, Short form (EPQ-RS and Adult Attachment Inventory (AAI. Data were analyzed using two way analysis of variance method.Results: Results indicate main effects of attachment styles and personality traits, so, individual with ambivalent insecure attachment experience more intensity of borderline traits than individual with avoidant insecure and secure attachments. Individual with high psychoticim and neuroticism traits experience more intensity of borderline characteristics than individual with extraversion personality traits. Also, there are no interactional effects of attachment styles and personality traits in relation to borderline characteristics. Conclusion: These findings reiterate contribution of childhood risk factors in developing borderline personality disorder, especially in children with emotionally vulnerability.

  15. Personality Characteristics, Job Stressors, and Job Satisfaction: Main and Interaction Effects on Psychological and Physical Health Conditions of Italian Schoolteachers.

    Science.gov (United States)

    Zurlo, Maria Clelia; Pes, Daniela; Capasso, Roberto

    2016-08-01

    The study proposed an application of the transactional model of stress in teaching elaborated by Travers and Cooper in 1996, and aimed to investigate the influence of personality characteristics (coping strategies, type A behaviors), situational characteristics (sources of pressure), and perceived job satisfaction in the prediction of teachers' psychophysical health conditions. The Italian version of the Teacher Stress Questionnaire was administered to 621 teachers. Logistic regression was used to evaluate significant main and interaction effects of personality characteristics, situational characteristics, and perceived job satisfaction on teachers' self-reported psychophysical health conditions. The findings highlighted specific coping strategies (focused on the problem, on innovation, and on hobbies and pastimes) and dimensions of job satisfaction (related to intrinsic aspects of job and to employee relations) buffering the negative effects of several job stressors. Type A behaviors and coping strategies focused on mobilized social support, suppression of stress, and not confronting the situation had main and interactions with negative effects on psychophysical health. Findings confirmed the necessity to run multi-factor research to analyze the different combinations of individual and situational variables implicated in negative health outcomes and to highlight the most significant buffering or increasing associations. © The Author(s) 2016.

  16. ON THE RELIABILITY OF STELLAR AGES AND AGE SPREADS INFERRED FROM PRE-MAIN-SEQUENCE EVOLUTIONARY MODELS

    International Nuclear Information System (INIS)

    Hosokawa, Takashi; Offner, Stella S. R.; Krumholz, Mark R.

    2011-01-01

    We revisit the problem of low-mass pre-main-sequence stellar evolution and its observational consequences for where stars fall on the Hertzsprung-Russell diagram (HRD). In contrast to most previous work, our models follow stars as they grow from small masses via accretion, and we perform a systematic study of how the stars' HRD evolution is influenced by their initial radius, by the radiative properties of the accretion flow, and by the accretion history, using both simple idealized accretion histories and histories taken from numerical simulations of star cluster formation. We compare our numerical results to both non-accreting isochrones and to the positions of observed stars in the HRD, with a goal of determining whether both the absolute ages and the age dispersions inferred from non-accreting isochrones are reliable. We show that non-accreting isochrones can sometimes overestimate stellar ages for more massive stars (those with effective temperatures above ∼3500 K), thereby explaining why non-accreting isochrones often suggest a systematic age difference between more and less massive stars in the same cluster. However, we also find the only way to produce a similar overestimate for the ages of cooler stars is if these stars grow from ∼0.01 M sun seed protostars that are an order of magnitude smaller than predicted by current theoretical models, and if the size of the seed protostar correlates systematically with the final stellar mass at the end of accretion. We therefore conclude that, unless both of these conditions are met, inferred ages and age spreads for cool stars are reliable, at least to the extent that the observed bolometric luminosities and temperatures are accurate. Finally, we note that the time dependence of the mass accretion rate has remarkably little effect on low-mass stars' evolution on the HRD, and that such time dependence may be neglected for all stars except those with effective temperatures above ∼4000 K.

  17. Genome scan for nonadditive heterotic trait loci reveals mainly underdominant effects in Saccharomyces cerevisiae.

    Science.gov (United States)

    Laiba, Efrat; Glikaite, Ilana; Levy, Yael; Pasternak, Zohar; Fridman, Eyal

    2016-04-01

    The overdominant model of heterosis explains the superior phenotype of hybrids by synergistic allelic interaction within heterozygous loci. To map such genetic variation in yeast, we used a population doubling time dataset of Saccharomyces cerevisiae 16 × 16 diallel and searched for major contributing heterotic trait loci (HTL). Heterosis was observed for the majority of hybrids, as they surpassed their best parent growth rate. However, most of the local heterozygous loci identified by genome scan were surprisingly underdominant, i.e., reduced growth. We speculated that in these loci adverse effects on growth resulted from incompatible allelic interactions. To test this assumption, we eliminated these allelic interactions by creating hybrids with local hemizygosity for the underdominant HTLs, as well as for control random loci. Growth of hybrids was indeed elevated for most hemizygous to HTL genes but not for control genes, hence validating the results of our genome scan. Assessing the consequences of local heterozygosity by reciprocal hemizygosity and allele replacement assays revealed the influence of genetic background on the underdominant effects of HTLs. Overall, this genome-wide study on a multi-parental hybrid population provides a strong argument against single gene overdominance as a major contributor to heterosis, and favors the dominance complementation model.

  18. Effect of humates in diet of dairy cows on the raw milk main components

    Directory of Open Access Journals (Sweden)

    Miroslava Potůčková

    2017-01-01

    Full Text Available The effect of supplemental humic substances (HS on the main milk components was investigated. A total of 10 dairy cows (Czech pied cattle, crossbred Czech pied cattle ´ Ayrshire and crossbred Czech pied cattle ´ Red Holstein were tested. Animals were randomly divided into 2 groups, control (C and experimental (E. Animals fed the same feed mixture and group E was additionally supplemented with HS (200 mg.kg-1 of product Humafit prepared from the Sakhalin Leonardite. The experimental period took 3 months. Cows were milked twice a day. The milk composition (lactose, fat, crude protein, pure protein and casein of every cow was monitored on days 0, 14, 28, 42, 56, 70 and 84 of the experiment. Pure protein content was determined by Kjeldahl method, other components were analysed using an infrared analyserMilkoScan FT 120. It was found that the crude protein, pure protein and casein content in milk of group E significantly (p <0.05 increased from the 56th day of the experimental period. Differences of the protein fraction contents in group C and of the dry matter, non-fat dry matter, lactose and fat content in both groups were non-significant (p <0.05.Higher protein and especially casein content in milk could be very important for the cheesemaking as it could increase the cheese yield. Normal 0 21 false false false CS X-NONE X-NONE

  19. Polymer Main-Chain Substitution Effects on the Efficiency of Nonfullerene BHJ Solar Cells

    KAUST Repository

    Firdaus, Yuliar; Maffei, Luna Pratali; Cruciani, Federico; Mü ller, Michael A.; Liu, Shengjian; Lopatin, Sergei; Wehbe, Nimer; Ngongang Ndjawa, Guy Olivier; Amassian, Aram; Laquai, Fré dé ric; Beaujuge, Pierre

    2017-01-01

    “Nonfullerene” acceptors are proving effective in bulk heterojunction (BHJ) solar cells when paired with selected polymer donors. However, the principles that guide the selection of adequate polymer donors for high-efficiency BHJ solar cells with nonfullerene acceptors remain a matter of some debate and, while polymer main-chain substitutions may have a direct influence on the donor–acceptor interplay, those effects should be examined and correlated with BHJ device performance patterns. This report examines a set of wide-bandgap polymer donor analogues composed of benzo[1,2-b:4,5-b′]dithiophene (BDT), and thienyl ([2H]T) or 3,4-difluorothiophene ([2F]T) motifs, and their BHJ device performance pattern with the nonfullerene acceptor “ITIC”. Studies show that the fluorine- and ring-substituted derivative PBDT(T)[2F]T largely outperforms its other two polymer donor counterparts, reaching power conversion efficiencies as high as 9.8%. Combining several characterization techniques, the gradual device performance improvements observed on swapping PBDT[2H]T for PBDT[2F]T, and then for PBDT(T)[2F]T, are found to result from (i) notably improved charge generation and collection efficiencies (estimated as ≈60%, 80%, and 90%, respectively), and (ii) reduced geminate recombination (being suppressed from ≈30%, 25% to 10%) and bimolecular recombination (inferred from recombination rate constant comparisons). These examinations will have broader implications for further studies on the optimization of BHJ solar cell efficiencies with polymer donors and a wider range of nonfullerene acceptors.

  20. Polymer Main-Chain Substitution Effects on the Efficiency of Nonfullerene BHJ Solar Cells

    KAUST Repository

    Firdaus, Yuliar

    2017-07-21

    “Nonfullerene” acceptors are proving effective in bulk heterojunction (BHJ) solar cells when paired with selected polymer donors. However, the principles that guide the selection of adequate polymer donors for high-efficiency BHJ solar cells with nonfullerene acceptors remain a matter of some debate and, while polymer main-chain substitutions may have a direct influence on the donor–acceptor interplay, those effects should be examined and correlated with BHJ device performance patterns. This report examines a set of wide-bandgap polymer donor analogues composed of benzo[1,2-b:4,5-b′]dithiophene (BDT), and thienyl ([2H]T) or 3,4-difluorothiophene ([2F]T) motifs, and their BHJ device performance pattern with the nonfullerene acceptor “ITIC”. Studies show that the fluorine- and ring-substituted derivative PBDT(T)[2F]T largely outperforms its other two polymer donor counterparts, reaching power conversion efficiencies as high as 9.8%. Combining several characterization techniques, the gradual device performance improvements observed on swapping PBDT[2H]T for PBDT[2F]T, and then for PBDT(T)[2F]T, are found to result from (i) notably improved charge generation and collection efficiencies (estimated as ≈60%, 80%, and 90%, respectively), and (ii) reduced geminate recombination (being suppressed from ≈30%, 25% to 10%) and bimolecular recombination (inferred from recombination rate constant comparisons). These examinations will have broader implications for further studies on the optimization of BHJ solar cell efficiencies with polymer donors and a wider range of nonfullerene acceptors.

  1. Establishment of land model at the Shika Nuclear Power Plant. Mainly, on rock board classification

    International Nuclear Information System (INIS)

    Katagawa, Hideki; Hashimoto, Toru; Hirano, Shuji

    1999-01-01

    In order to grasp engineering properties of basic land of constructions, there is rock board classification as a method to classify whole of rock board to some groups considerable to be nearly equal on its properties. Among the method, various methods in response to its aim and characteristics are devised, and for a classification to hard rock board, the Denken type rock board classification considering degree of weathering to its main element and so forth are well known. The basic rock board of the Shika Nuclear Power Plant is composed of middle and hard types of rock, and its weathering is limited to its shallow portion, most of which are held at fresh condition. For such land, a new classification standard in response to characteristics of land was established. Here were introduced on a progress to establish a new classification standard, its application results and rock board properties. (G.K.)

  2. Effects of the Pressurized Water Reactor Main Steam Line Break Location on the Blowdown Loading

    International Nuclear Information System (INIS)

    Jo, Jong Chull; Kang, Soon Ho; Chan, Won Joon

    2016-01-01

    The thermal hydraulic analysis has been performed generally using a simple lumped model or one dimensional numerical model. However, those models have limitations in predicting the transient variations of the steam velocity, pressure and hydrodynamic load at a local point and the most conservative condition. Furthermore, it cannot be confirmed if the blowdown loads predicted by either of the models are conservative to evaluate every part of the SG internal structures. In this study, the transient hydraulic response of the SG secondary side to the MSLB case where the pipe break is assumed to occur at the SG outlet nozzle end, another weld point on the MSL, was numerically simulated using a CFD code. The present CFD calculation results was compared with those in ref. to investigate the effect of break location (friction loss) on the blowdown load in the SG secondary side. The result shows that the friction loss along the steam line span between the SG nozzle end and the MSIV would cause reduction in steam velocity disturbance or dynamic pressure. It implies that the consequence of the MSLB at the SG nozzle end would be much severer that those of other MSLB cases where the break locations are far from the SG. Therefore, to assure a conservative safety evaluation of the SG structural integrity, the blowdown loading on the SG internal structures including tubes during a MSLB accident in terms of the transient steam velocity, dynamic pressure and decompression wave fluctuations should be assessed for the MSLB case where the break is assumed to occur at the SG nozzle end.

  3. Effects of the Pressurized Water Reactor Main Steam Line Break Location on the Blowdown Loading

    Energy Technology Data Exchange (ETDEWEB)

    Jo, Jong Chull; Kang, Soon Ho; Chan, Won Joon [KAERI, Daejeon (Korea, Republic of)

    2016-05-15

    The thermal hydraulic analysis has been performed generally using a simple lumped model or one dimensional numerical model. However, those models have limitations in predicting the transient variations of the steam velocity, pressure and hydrodynamic load at a local point and the most conservative condition. Furthermore, it cannot be confirmed if the blowdown loads predicted by either of the models are conservative to evaluate every part of the SG internal structures. In this study, the transient hydraulic response of the SG secondary side to the MSLB case where the pipe break is assumed to occur at the SG outlet nozzle end, another weld point on the MSL, was numerically simulated using a CFD code. The present CFD calculation results was compared with those in ref. to investigate the effect of break location (friction loss) on the blowdown load in the SG secondary side. The result shows that the friction loss along the steam line span between the SG nozzle end and the MSIV would cause reduction in steam velocity disturbance or dynamic pressure. It implies that the consequence of the MSLB at the SG nozzle end would be much severer that those of other MSLB cases where the break locations are far from the SG. Therefore, to assure a conservative safety evaluation of the SG structural integrity, the blowdown loading on the SG internal structures including tubes during a MSLB accident in terms of the transient steam velocity, dynamic pressure and decompression wave fluctuations should be assessed for the MSLB case where the break is assumed to occur at the SG nozzle end.

  4. The effect of using a fungicide along with bactericide in the main ...

    African Journals Online (AJOL)

    quarternized compounds), and a fungicide (2-thiocyanomethylthio benzothiazole based) commonly used in Turkish leather industry were chosen. The bactericides were added into the main soaking float with and without different concentrations of fungicide. In each trial, liquor samples were taken at the end of the main ...

  5. Predicting forest dieback in Maine, USA: a simple model based on soil frost and drought

    Science.gov (United States)

    Allan N.D. Auclair; Warren E. Heilman; Blondel. Brinkman

    2010-01-01

    Tree roots of northern hardwoods are shallow rooted, winter active, and minimally frost hardened; dieback is a winter freezing injury to roots incited by frost penetration in the absence of adequate snow cover and exacerbated by drought in summer. High soil water content greatly increases conductivity of frost. We develop a model based on the sum of z-scores of soil...

  6. Refining the model of barrier island formation along a paraglacial coast in the Gulf of Maine

    Science.gov (United States)

    Hein, Christopher J.; FitzGerald, Duncan M.; Carruthers, Emily A.; Stone, Byron D.; Barnhardt, Walter A.; Gontz, Allen M.

    2012-01-01

    Details of the internal architecture and local geochronology of Plum Island, the longest barrier in the Gulf of Maine, have refined our understanding of barrier island formation in paraglacial settings. Ground-penetrating radar and shallow-seismic profiles coupled with sediment cores and radiocarbon dates provide an 8000-year evolutionary history of this barrier system in response to changes in sediment sources and supply rates as well as variability in the rate of sea-level change. The barrier sequence overlies tills of Wisconsinan and Illinoian glaciations as well as late Pleistocene glaciomarine clay deposited during the post-glacial sea-level highstand at approximately 17 ka. Holocene sediment began accumulating at the site of Plum Island at 7–8 ka, in the form of coarse fluvial channel-lag deposits related to the 50-m wide erosional channel of the Parker River that carved into underlying glaciomarine deposits during a lower stand of sea level. Plum Island had first developed in its modern location by ca. 3.6 ka through onshore migration and vertical accretion of reworked regressive and lowstand deposits. The prevalence of southerly, seaward-dipping layers indicates that greater than 60% of the barrier lithosome developed in its modern location through southerly spit progradation, consistent with a dominantly longshore transport system driven by northeast storms. Thinner sequences of northerly, landward-dipping clinoforms represent the northern recurve of the prograding spit. A 5–6-m-thick inlet-fill sequence was identified overlying the lower stand fluvial deposit; its stratigraphy captures events of channel migration, ebb-delta breaching, onshore bar migration, channel shoaling and inlet infilling associated with the migration and eventual closure of the inlet. This inlet had a maximum cross-sectional area of 2800 m2 and was active around 3.5–3.6 ka. Discovery of this inlet suggests that the tidal prism was once larger than at present. Bay infilling

  7. Aqueous photochemical degradation of hydroxylated PAHs: Kinetics, pathways, and multivariate effects of main water constituents

    Energy Technology Data Exchange (ETDEWEB)

    Ge, Linke; Na, Guangshui [Key Laboratory for Ecological Environment in Coastal Areas (SOA), National Marine Environmental Monitoring Center, Dalian 116023 (China); Chen, Chang-Er [Lancaster Environment Centre, Lancaster University, Lancaster LA1 4YQ (United Kingdom); Li, Jun [Key Laboratory for Ecological Environment in Coastal Areas (SOA), National Marine Environmental Monitoring Center, Dalian 116023 (China); College of Marine Science, Shanghai Ocean University, Shanghai 201306 (China); Ju, Maowei; Wang, Ying; Li, Kai [Key Laboratory for Ecological Environment in Coastal Areas (SOA), National Marine Environmental Monitoring Center, Dalian 116023 (China); Zhang, Peng, E-mail: pzhang@nmemc.org.cn [Key Laboratory for Ecological Environment in Coastal Areas (SOA), National Marine Environmental Monitoring Center, Dalian 116023 (China); Yao, Ziwei [Key Laboratory for Ecological Environment in Coastal Areas (SOA), National Marine Environmental Monitoring Center, Dalian 116023 (China)

    2016-03-15

    PAHs. • Hydroxylated PAHs intrinsically photodegrade fast in sunlit surface waters. • Reaction types and transformation pathways of 9-Hydroxyfluorene were clarified. • Photolysis kinetics was affected by multivariate effects of main water constituents. • The photomodified toxicity of 9-Hydroxyfluorene was examined using Vibrio fischeri.

  8. Regulation models for district heating. Main report; Denmark; Reguleringsmodeller for fjernvarmen. Hovedrapport

    Energy Technology Data Exchange (ETDEWEB)

    2012-02-15

    With regard to choice of model for the regulation of district heating prices the report points out that a detailed analysis of a cost+ model could be considered. Such an analysis could provide further definition of the extended right to recoup the investment for heating companies, the shaping of the possibility of recognition of opportunity costs and the fixed cost allocation, and the clarified definition of necessary costs. The report also suggests that a price cap regulation or a completely free pricing in the entire sector is hardly appropriate forms of regulation. The report's analysis clearly shows that the choice of price regulation in the heat sector has impact on the incentives in terms of investment, green conversion, etc. It also appears that the different regulatory models have very different advantages and disadvantages, and lessons learned from other sectors and abroad show that changing price regulation rules can be a difficult and lengthy process with unintended consequences along the way. (LN)

  9. Wildfire risk for main vegetation units in a biodiversity hotspot: modeling approach in New Caledonia, South Pacific.

    Science.gov (United States)

    Gomez, Céline; Mangeas, Morgan; Curt, Thomas; Ibanez, Thomas; Munzinger, Jérôme; Dumas, Pascal; Jérémy, André; Despinoy, Marc; Hély, Christelle

    2015-01-01

    Wildfire has been recognized as one of the most ubiquitous disturbance agents to impact on natural environments. In this study, our main objective was to propose a modeling approach to investigate the potential impact of wildfire on biodiversity. The method is illustrated with an application example in New Caledonia where conservation and sustainable biodiversity management represent an important challenge. Firstly, a biodiversity loss index, including the diversity and the vulnerability indexes, was calculated for every vegetation unit in New Caledonia and mapped according to its distribution over the New Caledonian mainland. Then, based on spatially explicit fire behavior simulations (using the FLAMMAP software) and fire ignition probabilities, two original fire risk assessment approaches were proposed: a one-off event model and a multi-event burn probability model. The spatial distribution of fire risk across New Caledonia was similar for both indices with very small localized spots having high risk. The patterns relating to highest risk are all located around the remaining sclerophyll forest fragments and are representing 0.012% of the mainland surface. A small part of maquis and areas adjacent to dense humid forest on ultramafic substrates should also be monitored. Vegetation interfaces between secondary and primary units displayed high risk and should represent priority zones for fire effects mitigation. Low fire ignition probability in anthropogenic-free areas decreases drastically the risk. A one-off event associated risk allowed localizing of the most likely ignition areas with potential for extensive damage. Emergency actions could aim limiting specific fire spread known to have high impact or consist of on targeting high risk areas to limit one-off fire ignitions. Spatially explicit information on burning probability is necessary for setting strategic fire and fuel management planning. Both risk indices provide clues to preserve New Caledonia hot spot of

  10. Main Quality Attributes of Monoclonal Antibodies and Effect of Cell Culture Components

    Science.gov (United States)

    Torkashvand, Fatemeh; Vaziri, Behrouz

    2017-05-01

    The culture media optimization is an inevitable part of upstream process development in therapeutic monoclonal antibodies (mAbs) production. The quality by design (QbD) approach defines the assured quality of the final product through the development stage. An important step in QbD is determination of the main quality attributes. During the media optimization, some of the main quality attributes such as glycosylation pattern, charge variants, aggregates, and low-molecular-weight species, could be significantly altered. Here, we provide an overview of how cell culture medium components affects the main quality attributes of the mAbs. Knowing the relationship between the culture media components and the main quality attributes could be successfully utilized for a rational optimization of mammalian cell culture media for industrial mAbs production.

  11. Effective radium concentration across the Main Central Thrust in the Nepal Himalayas

    International Nuclear Information System (INIS)

    Girault, Frederic; Perrier, Frederic; Gajurel, Ananta Prasad; Bhattarai, Mukunda; Koirala, Bharat Prasad; Bollinger, Laurent; Fort, Monique; France-Lanord, Christian

    2012-01-01

    Effective radium concentration (EC(Ra)) of 622 rock samples from 6 different sites in the Nepal Himalayas was measured in the laboratory using radon accumulation experiments. These sites, located from Lower Dolpo in Western Nepal to Eastern Nepal, are divided into 9 transects which cut across the Main Central Thrust zone (MCT zone) separating low-grade metamorphic Lesser Himalayan Sequence (LHS) units to the south and higher-grade metamorphic Greater Himalayan Sequence (GHS) units to the north. This boundary remains difficult to define and is the subject of numerous debates. EC(Ra) values range from 0.03 ± 0.03 to 251.6 ± 4.0 Bq kg -1 , and appear to be representative of the formation and clearly related to the local lithology. For example, for the Upper Trisuli and Langtang Valleys site in Central Nepal, the most studied place with 350 available EC(Ra) values, LHS rocks are characterized by a mean value of 5.3 ± 1.3 Bq kg -1 while GHS rocks of Formations I and II show significantly lower values with a mean value of 0.69 ± 0.11 Bq kg -1 , thus leading to a LHS/GHS EC(Ra) ratio of 7.8 ± 2.2. This behavior was systematically confirmed by other transects (ratio of 7.9 ± 2.2 in all other sites), with a threshold ECRa value, separating LHS from GHS, of 0.8 Bq kg -1 , thus bringing forward a novel method to characterize, within the MCT shear zone, which rocks belong to the GHS and LHS units. In addition, Ulleri augen gneiss, belonging to LHS rocks, occurred in several transects and were characterized by high EC(Ra) values (17.9 ± 4.3 Bq kg -1 ), easy to distinguish from the GHS gneisses, characterized by low EC(Ra) values at the bottom of the GHS, thus providing a further argument to locate the MCT. The measurement of EC(Ra) data, thus, provides a cost-effective method which can be compared with neodymium isotopic anomalies or estimates of the peak metamorphic temperature. This study, therefore, shows that the measurements of EC(Ra) provides additional information

  12. THE MODEL OF IDENTIFICATION OF THE PROBLEM MAIN CAUSE SET OF VARIATION

    Directory of Open Access Journals (Sweden)

    Nenad Miric

    2008-06-01

    Full Text Available The term Lean has been widely used in today's product manufacturing and service delivery environments. In its fundamental nature the Lean Philosophy continuously strives for elimination of any kind of waste that exists in such environments. There are six basic strategies [1] related to the Lean Philosophy: Workplace Safety & Order & Cleanliness, JIT production, Six Sigma Quality, Empowered Teams, Visual Management and Pursuit of Perfection. On the journey of sustaining the lean supporting strategies there are many problems, or opportunities as Lean Practitioners call them. The value of some strategies highly depends on the efficiency of the problem solving techniques used to overcome the emerging issues. JIT production is difficult to imagine without a system that supports a high level of operational readiness with equipment uptime above 98%. Six Sigma level of quality, even when built into a product or system design, still undergoes the challenges of day to day operations and the variability brought with it. This variability is the source of waste and lean systems culture strives for continuous reduction of it. Empowered Teams properly trained to recognize the real cause of the problems and their Pursuit of Perfection culture are one of the corner stones of Lean Philosophy sustainability. Their ability to work with Problem Solvers and understand the difference between the "cure of the symptoms" approach versus "problem root cause identification" is one of the distinctions between Lean and Mass operations. Among the series of Statistical Engineering To ols this paper will show one of the techniques that proved to be powerful in the identification of the Set of Variation that contains the Main Cause of the new problems that arise in daily operations. This technique is called Multi - Vari. Multi - Vari is th e statistical engineering method used to analyze the set of data acquired in an organized manner. The set could be analyzed graphically or

  13. Intestinal Transportations of Main Chemical Compositions of Polygoni Multiflori Radix in Caco-2 Cell Model

    Directory of Open Access Journals (Sweden)

    Jie Yu

    2014-01-01

    Full Text Available Context. Polygoni Multiflori Radix (PMR is originated from the root of Polygonum multiflorum Thunb. and used in oriental countries for centuries. However, little researches pay close attention to the absorption of its major constituents. Objective. Transepithelial transport of TSG, RL, PL, and four anthraquinones is carried out. Materials and Methods. Caco-2 cell monolayer, which represented a well-established model for the study of intestinal transport of nutrients and xenobiotics, was used in this paper. Results. The apparent permeability coefficients (Papp in the Caco-2 cell monolayers were TSG (2.372 × 10−9 < EG (2.391 × 10−9 < EN (2.483 × 10−9 < PL (4.917 × 10−9 < RN (1.707 × 10−8 < RL (1.778 × 10−8 < AE (1.952 × 10−8. Thus, RN, RL, and AE were considered partly absorbed, while other constituents were hardly absorbed. Discussion and Conclusion. Glycosides showed poor permeabilities than aglycones. In the meantime, TSG and EN gave out poor recovery rates in this assay, which indicated that TSG and EN may accumulate or metabolise in the Caco-2 cells. In silico prediction indicated that Gibbs energy (r=0.751, p<0.05 and heat of form (r=0.701, p<0.05 were strongly positively correlated with Papp.

  14. Oxidative Stress Implications in the Affective Disorders: Main Biomarkers, Animal Models Relevance, Genetic Perspectives, and Antioxidant Approaches.

    Science.gov (United States)

    Balmus, Ioana Miruna; Ciobica, Alin; Antioch, Iulia; Dobrin, Romeo; Timofte, Daniel

    2016-01-01

    The correlation between the affective disorders and the almost ubiquitous pathological oxidative stress can be described in a multifactorial way, as an important mechanism of central nervous system impairment. Whether the obvious changes which occur in oxidative balance of the affective disorders are a part of the constitutive mechanism or a collateral effect yet remains as an interesting question. However it is now clear that oxidative stress is a component of these disorders, being characterized by different aspects in a disease-dependent manner. Still, there are a lot of controversies regarding the relevance of the oxidative stress status in most of the affective disorders and despite the fact that most of the studies are showing that the affective disorders development can be correlated to increased oxidative levels, there are various studies stating that oxidative stress is not linked with the mood changing tendencies. Thus, in this minireview we decided to describe the way in which oxidative stress is involved in the affective disorders development, by focusing on the main oxidative stress markers that could be used mechanistically and therapeutically in these deficiencies, the genetic perspectives, some antioxidant approaches, and the relevance of some animal models studies in this context.

  15. Effects of a Tree Diagram on Students' Comprehension of Main Ideas in an Expository Text with Multiple Themes.

    Science.gov (United States)

    Guri-Rozenblit, Sarah

    1989-01-01

    Examines the effect of a tree diagram on college students' comprehension of main ideas in a social sciences expository text. Concludes that the tree diagram significantly improved comprehension of main ideas and relations between elements, irrespective of the students' initial verbal and visual aptitudes. (RS)

  16. Vulnerability and risk evaluation of agricultural nitrogen pollution for Hungary's main aquifer using DRASTIC and GLEAMS models.

    Science.gov (United States)

    Leone, A; Ripa, M N; Uricchio, V; Deák, J; Vargay, Z

    2009-07-01

    In recent years, the significant improvement in point source depuration technologies has highlighted problems regarding, in particular, phosphorus and nitrogen pollution of surface and groundwater caused by agricultural non-point (diffuse) sources (NPS). Therefore, there is an urgent need to determine the relationship between agriculture and chemical and ecological water quality. This is a worldwide problem, but it is particularly relevant in countries, such as Hungary, that have recently become members of the European Community. The Italian Foreign Ministry has financed the PECO (Eastern Europe Countries Project) projects, amongst which is the project that led to the present paper, aimed at agricultural sustainability in Hungary, from the point of view of NPS. Specifically, the aim of the present work has been to study nitrates in Hungary's main aquifer. This study compares a model showing aquifer intrinsic vulnerability to pollution (using the DRASTIC parameter method; Aller et al. [Aller, L., Truman, B., Leher, J.H., Petty, R.J., 1986. DRASTIC: A Standardized System for Evaluating Ground Water Pollution Potential Using Hydrogeologic Settings. US NTIS, Springfield, VA.]) with a field-scale model (GLEAMS; Knisel [Knisel, W.G. (Ed.), 1993. GLEAMS--Groudwater Leaching Effects of Agricultural Management Systems, Version 3.10. University of Georgia, Coastal Plain Experimental Station, Tifton, GA.]) developed to evaluate the effects of agricultural management systems within and through the plant root zone. Specifically, GLEAMS calculates nitrate nitrogen lost by runoff, sediment and leachate. Groundwater monitoring probes were constructed for the project to measure: (i) nitrate content in monitored wells; (ii) tritium (3H) hydrogen radioisotope, as a tool to estimate the recharge conditions of the shallow groundwater; (iii) nitrogen isotope ratio delta15N, since nitrogen of organic and inorganic origin can easily be distinguished. The results obtained are satisfactory

  17. A network analysis of the Chinese medicine Lianhua-Qingwen formula to identify its main effective components.

    Science.gov (United States)

    Wang, Chun-Hua; Zhong, Yi; Zhang, Yan; Liu, Jin-Ping; Wang, Yue-Fei; Jia, Wei-Na; Wang, Guo-Cai; Li, Zheng; Zhu, Yan; Gao, Xiu-Mei

    2016-02-01

    Chinese medicine is known to treat complex diseases with multiple components and multiple targets. However, the main effective components and their related key targets and functions remain to be identified. Herein, a network analysis method was developed to identify the main effective components and key targets of a Chinese medicine, Lianhua-Qingwen Formula (LQF). The LQF is commonly used for the prevention and treatment of viral influenza in China. It is composed of 11 herbs, gypsum and menthol with 61 compounds being identified in our previous work. In this paper, these 61 candidate compounds were used to find their related targets and construct the predicted-target (PT) network. An influenza-related protein-protein interaction (PPI) network was constructed and integrated with the PT network. Then the compound-effective target (CET) network and compound-ineffective target network (CIT) were extracted, respectively. A novel approach was developed to identify effective components by comparing CET and CIT networks. As a result, 15 main effective components were identified along with 61 corresponding targets. 7 of these main effective components were further experimentally validated to have antivirus efficacy in vitro. The main effective component-target (MECT) network was further constructed with main effective components and their key targets. Gene Ontology (GO) analysis of the MECT network predicted key functions such as NO production being modulated by the LQF. Interestingly, five effective components were experimentally tested and exhibited inhibitory effects on NO production in the LPS induced RAW 264.7 cell. In summary, we have developed a novel approach to identify the main effective components in a Chinese medicine LQF and experimentally validated some of the predictions.

  18. EMBIO - The Danish Energy Agency's model for economic and environmental evaluation of bio-fuels. Main report

    International Nuclear Information System (INIS)

    1997-01-01

    A methodological concept is established for a life-cycle based model which can be used for socio- and private economic and environmental assessment of automotive bio-fuels. The calculation method must be able to calculate socio-economic, energy, environmental, and other consequences by alternative productions and uses of bio-fuels in a way that makes it possible to compare advantages and disadvantages across alternative production technologies. Furthermore it must be possible to perform private cost-benefit calculations from the model. The model must also be able to evaluate specific bio-fuel project, and therefore the method has been developed in close interaction with analyses of two bio-fuel projects. The main emphasis in the development of the model has been put on the relation between CO 2 reduction and economics. One main result of the model analyses is therefore the calculated shadow price for the CO 2 reduction which expresses the socio-economic costs per ton saved CO 2 . The socio-economic analyses of the model do not include a monetary account of other environmental impacts than the CO 2 emission or other relevant consequences like impacts on employment, balance of payments etc. Thus the socio-economic analyses cannot be the only decision basis for assessing bio-fuel projects. The other environmental aspects are treated only briefly. The model may, however, very easily be extended to a more formalized account of these other aspects. The model may be used for specific experimental projects and for implementation of large full-scale projects. The model development has been limited to use of bio-fuels in the transportation sector. The model may, however, also be used for evaluating bio-fuels in general or other biomass-based energy use in other sectors. (LN) 113 refs

  19. The effects of improvement of the main shaft on the operating conditions of the Agnew turbine

    Energy Technology Data Exchange (ETDEWEB)

    Yassi, Y. [Iranian Research Organization for Science and Technology (IROST), Tehran (Iran)

    2009-10-15

    Agnew turbine is a 45 axial flow Kaplan type micro hydro. The turbine was designed by an ex-lecturer of the Univ. of Glasgow, to operate without guide vanes. Later due to a joint research program between the Iranian Research Organization for Science and Technology (IROST) and the Univ. of Glasgow it was developed to operate under low head and limited flow potentials in Iran. The original design of the main shaft of the turbine was supported by a bearing housing consisting of three bearings outside the main casing, leaving the rest of the shaft, hub and the runner without any supports inside the turbine.Later a suitable support near the runner and inside the casing was designed and installed. Standard turbine tests showed considerable improvements in operating characteristics of the turbine due to these design modifications. This paper presents details of these improvements and the related outcomes. (author)

  20. The effects of improvement of the main shaft on the operating conditions of the Agnew turbine

    International Nuclear Information System (INIS)

    Yassi, Y.

    2009-01-01

    Agnew turbine is a 45 deg. axial flow Kaplan type micro hydro. The turbine was designed by an ex-lecturer of the University of Glasgow, to operate without guide vanes. Later due to a joint research program between the Iranian Research Organization for Science and Technology (IROST) and the University of Glasgow it was developed to operate under low head and limited flow potentials in Iran. The original design of the main shaft of the turbine was supported by a bearing housing consisting of three bearings outside the main casing, leaving the rest of the shaft, hub and the runner without any supports inside the turbine .Later a suitable support near the runner and inside the casing was designed and installed. Standard turbine tests showed considerable improvements in operating characteristics of the turbine due to these design modifications. This paper presents details of these improvements and the related outcomes.

  1. Effects of Layering Milling Technology on Distribution of Green Wheat Main Physicochemical Parameters

    OpenAIRE

    Tian, Shuang-Qi; Li, Yong-Heng; Chen, Zhi-Cheng; Qiao, Yong-Feng

    2017-01-01

    With layered milling flour technology, the efficiency of the nutrient distribution and hardness was demonstrated with the green and normal wheat separation milling. The results showed that the total content of amino acid in green wheat was 8.3%–13.0% higher compared to the common wheat. Comparing the main nutriments Se, Fe, and Ca between green wheat and common wheat, the results showed that different milling treatment methods are capable of separating the different wheat flour from endosperm...

  2. The effect of a local source on the composition of precipitation in south-central Maine

    Science.gov (United States)

    Scott D. Boyce; Samuel S. Butcher

    1976-01-01

    Bulk precipitation samples were collected from ten sites in south-central Maine during the period 18 June to 30 September 1974. Data from the chemical analyses of the precipitation were used to determine regional deposition patterns of the ionic constituents. Acidic pH values ranging from 3.8 to 5.0 are characteristic of the region, but relatively alkaline pH values of...

  3. Effects of main traits of sweet sorghum irradiated by carbon ions

    International Nuclear Information System (INIS)

    Li Wenjian; He Jingyu; Liu Qingfang; Yu Lixia; Dong Xicun

    2009-01-01

    To investigate the influence of carbon ion irradiation on important agronomic characters of sweet sorghum, dry seeds of Sweet Sorghum BJ0601 and BJ0602 were irradiated by 100 MeV/u 12 C +6 ion beam to different doses at Heavy Ion Accelerator National Laboratory in Lanzhou (HIANLL). When matured, the main traits of sweet sorghum were measured. The correlation coefficient of five main agronomic characters, i.e. number of node, plant height, stalk diameter, sugar content and stem weight per plant, were analyzed using the SPSS 13.0 software. The results indicated that the obvious influence of sweet sorghum irradiated by carbon ion beam was observed. In addition, the correlation of main traits was studied. This study may provide rudimental data to select novel variety of sweet sorghum suited for fuel ethanol production. In addition, the average of sugar content of early mutant BJ0601-1 is higher than BJ0601 in M2, and the sugar content of sweet sorghum may be improved by carbon ion beam irradiation. (authors)

  4. Main findings

    International Nuclear Information System (INIS)

    2014-01-01

    Licensing regimes vary from country to country. When the license regime involves several regulators and several licenses, this may lead to complex situations. Identifying a leading organisation in charge of overall coordination including preparation of the licensing decision is a useful practice. Also, if a stepwise licensing process is implemented, it is important to fix in legislation decisions and/or time points and to identify the relevant actors. There is considerable experience in civil and mining engineering that can be applied when constructing a deep geological disposal facility. Specific challenges are, however, the minimization of disturbances to the host rock and the understanding of its long-term behavior. Construction activities may affect the geo-hydraulic and geochemical properties of the various system components which are important safety features of the repository system. Clearly defined technical specifications and an effective quality management plan are important in ensuring successful repository implementation which is consistent with safety requirements. Monitoring plan should also be defined in advance. The regulatory organization should prepare itself to the licensing review before construction by allocating sufficient resources. It should increase its competence, e.g., by interacting early with the implementer and through its own R and D. This will allow the regulator to define appropriate technical conditions associated to the construction license and to elaborate a relevant inspection plan of the construction work. After construction, obtaining the operational license is the most important and crucial step. Main challenges include (a) establishing sufficient confidence so that the methods for closing the individual disposal units comply with the safety objectives and (b) addressing the issue of ageing of materials during a 50-100 years operational period. This latter challenge is amplified when reversibility/retrievability is required

  5. Effects of main-sequence mass loss on the turnoff ages of globular clusters

    International Nuclear Information System (INIS)

    Guzik, J.A.

    1989-01-01

    Willson, Bowen, and Struck-Marcell have proposed that globular cluster main-sequence turnoff ages can be reconciled with the lower ages of the Galaxy and universe deduced from other methods by incorporating an epoch of early main-sequence mass-loss by stars of spectral types A through early-F. The proposed mass loss is pulsation-driven, and facilitated by rapid rotation. This paper presents stellar evolution calculations of Pop. II (Z = 0.001) mass-losing stars of initial mass 0.8 to 1.6 M circle dot , with exponentially-decreasing mass loss rates of e-folding times 0.5 to 2.0 Gyr, evolving to a final mass of 0.7 M circle dot . The calculations indicate that a globular cluster with apparent turnoff age 18 Gyr could have an actual age as low as ∼12 Gyr. Observational implications that may help to verify the hypothesis, e.g. low C/N abundance ratios among red giants following first dredge-up, blue stragglers, red giant deficiencies, and signatures in cluster mass/luminosity functions, are also discussed.25 refs., 4 figs., 3 tabs

  6. Temperature factors effect on occurrence of stress corrosion cracking of main gas pipeline

    Science.gov (United States)

    Nazarova, M. N.; Akhmetov, R. R.; Krainov, S. A.

    2017-10-01

    The purpose of the article is to analyze and compare the data in order to contribute to the formation of an objective opinion on the issue of the growth of stress corrosion defects of the main gas pipeline. According to available data, a histogram of the dependence of defects due to stress corrosion on the distance from the compressor station was constructed, and graphs of the dependence of the accident density due to stress corrosion in the winter and summer were also plotted. Data on activation energy were collected and analyzed in which occurrence of stress corrosion is most likely constructed, a plot of activation energy versus temperature is plotted, and the process of occurrence of stress corrosion by the example of two different grades of steels under the action of different temperatures was analyzed.

  7. Effects of aging and service wear on main steam isolation valves and valve operators

    International Nuclear Information System (INIS)

    Clark, R.L.

    1996-03-01

    In recent years main steam isolation valve (MSIV operating problems have resulted in significant operational transients (e.g., spurious reactor trips, steam generator dry out, excessive valve seat leakage), increased cost, and decreased plant availability. A key ingredient to an engineering-oriented reliability improvement effort is a thorough understanding of relevant historical experience. A detailed review of historical failure data available through the Institute of Nuclear Power Operation's Nuclear Plant Reliability Data System has been conducted for several types of MSIVs and valve operators for both boiling-water reactors and pressurized-water reactors. The focus of this review is on MSIV failures modes, actuator failure modes, consequences of failure on plant operations, method of failure detection, and major stressors affecting both valves and valve operators

  8. Results of 3-dimensional structural FE-modeling of the coil end-regions of the LHC main dipoles

    CERN Document Server

    Hoeck, U; Schillo, M; Perini, D; Siegel, N

    2000-01-01

    The transition region between the straight part and the ends of the coils of the LHC model and prototype dipole magnets are often identified as the origin of training quenches. In order to study how the discontinuities in the material properties of these regions affect coil pre-stress and possibly gain more insight in the quench behavior, a program was set up at CERN to analyze by 3D-FEM these particular regions. The ACCEL team, who performed a similar analysis for the main quadrupoles of the Superconducting Supercollider SSC, is entrusted with this program. In this paper we report on the results of 3D-modeling and analysis of the coil return end region, including the complete coil mass, of a 1-m single bore model magnet. This magnet represents all relevant features of the "two-in-one" LHC main dipole design concerning the winding configuration, the collar pack, the yoke, and the outer shell representing the He-vessel. The transition region between coil ends and straight section is modeled by slicing the magn...

  9. Effectiveness of Emittance Bumps in the NLC and US Cold LC Main Linear Accelerators (LCC-0138)

    International Nuclear Information System (INIS)

    Tenenbaum, P

    2004-01-01

    We report on a series of studies on the effectiveness of closed orbit bumps in the linacs of the NLC and the USColdLC. In the first study, emittance dilutions of a pure-wakefield or pure-dispersion character are introduced in each linac, and a set of emittance bumps is tested to determine the most effective bump location in the linac, and the net effectiveness. In the second study, a more realistic set of dilutions are introduced and the wakefield bumps used in the first study are applied

  10. THEORETICAL FEATURES REGARDING THE EVOLUTION OVER TIME OF THE MAIN COMMUNICATION MODELS USED FOR THE STUDY OF MASS COMMUNICATION

    Directory of Open Access Journals (Sweden)

    Irina IOSUB

    2016-06-01

    Full Text Available In the context of increasingly accelerated development of technology and particularly of the Internet, mass communication acquires new meanings. This article proposes a brief theoretical approach to the study of mass communication as it was treated in the specific literature of the 50s and 60s, when there was little talk about new technologies. However, many features identified since then still retain their topicality and for this reason it is interesting to note the evolution over time of the main communication models that were and some of them still are used for the study of mass communication. They are relevant to the context in which a complete study of mass communication is required, not only from the perspective of the present, but also from the period in which it was outlined. Thus, this article is divided into three main sections: the first part represents the meaning of communication in a general sense, so that the second part to represent the mass communication process and its characteristics, and the last part to represent the main models of communication in the order in which they have occurred, and especially aiming at new features that each of them brought.

  11. The effect of using a fungicide along with bactericide in the main ...

    African Journals Online (AJOL)

    STORAGESEVER

    2008-11-05

    Nov 5, 2008 ... bacterial growth occurred on the media. Key words: Leather industry, soaking process, bacteria number, fungi number ... production. Then, they are ..... The effect of conservation defects on the suede quality of double- face.

  12. Towards the sustainable management of thuya (Tetraclinis articulata (Vahl.) Mast.) forests in Tunisia: models for main tree attributes

    Energy Technology Data Exchange (ETDEWEB)

    Calama, R.; Sanchez-Gonzalez, M.; Garchi, S.; Ammari, Y.; Canellas, I.; Tahar, S.

    2012-11-01

    The thuya (Tetraclinis articulata (Vahl.) Mast.) forests are one of the most important ecosystems in semiarid environments in north-western Africa, providing important economic profit and social services to local populations. However, lack of tools aiding sustainable management of these forests is detected. In the present work models for the main tree attributes as total height, crown diameter, height to crown base and stem form are developed for the species, using data from a net of plots installed in JbelLattrech region, in the NE Tunisia. Presented models allow characterizing the actual state and timber production of forests by using variables measured in typical forest inventories and conform a preliminary step for the future development of dynamic growth models. (Author) 18 refs.

  13. Development of a model of the main turbine of the CNLV for RELAP/SCAPSIM 3.4

    International Nuclear Information System (INIS)

    Mendoza M, R.; Ortiz V, J.; Araiza M, E.

    2011-11-01

    With the objective of simulating the plant balance of the nuclear power plant of Laguna Verde (CNLV), was developed a simplified model of the turbine of high pressure and turbines of low pressure to be integrated to the model of the NSSS that is used in the code RELAP/SCDAPSIM Mod. 3.4, with the purpose of simulating the stationary state and transitory events to conditions of 2027 MWt. In the first part of this work a brief description of the main turbine of the CNLV is given. Later on, the developed model is described to be used in the mentioned code. At the end, the results of the code executions are presented as well as the comparisons against the nominal values of the CNLV in stationary state, to the indicated power. (Author)

  14. Biocidal effects of Piper hispidinervum (Piperaceae) essential oil and synergism among its main components.

    Science.gov (United States)

    Andrés, M F; Rossa, G E; Cassel, E; Vargas, R M F; Santana, O; Díaz, C E; González-Coloma, A

    2017-11-01

    In this study we evaluated the effect of a pressure gradient (1-2 atm) in the extraction and composition of the essential oil (EO) of Piper hispidinervum by steam distillation. We also evaluated the insect antifeedant effects (Spodoptera littoralis, Leptinotarsa decemlineata, Myzus persicae and Rhopalosiphum padi) and nematicidal activity (Meloidogyne javanica) of the oils, their major components and their synergistic interactions. Safrole was the major component (78-81%) followed by terpinolene (5-9%). The EOs tested were effective insect antifeedants. Safrole, explained most of the insect antifeedant action of P. hispidinervum EOs. When safrole and terpinolene were tested in binary combinations, low ratios of safrole improved the antifeedant effects of terpinolene. P. hispidinervum EOs caused higher mortality of M. javanica juveniles than their major components. In binary combinations, low ratios of terpinolene increased the nematicidal effects of safrole. The EO treatment strongly suppressed nematode egg hatching and juvenile infectivity. P. hispidinervum EOs affected the germination of S. lycopersicum and L. sativa mostly at 24 h of treatment, being L. sativa the most sensitive. Safrole moderately affected germination and root growth of L. sativa, S. lycopersicum and L. perenne. Terpinolene only affected S. lycopersicum root growth. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. Effect of functionalization of boron nitride flakes by main group metal clusters on their optoelectronic properties

    Science.gov (United States)

    Chakraborty, Debdutta; Chattaraj, Pratim Kumar

    2017-10-01

    The possibility of functionalizing boron nitride flakes (BNFs) with some selected main group metal clusters, viz. OLi4, NLi5, CLi6, BLI7 and Al12Be, has been analyzed with the aid of density functional theory (DFT) based computations. Thermochemical as well as energetic considerations suggest that all the metal clusters interact with the BNF moiety in a favorable fashion. As a result of functionalization, the static (first) hyperpolarizability (β ) values of the metal cluster supported BNF moieties increase quite significantly as compared to that in the case of pristine BNF. Time dependent DFT analysis reveals that the metal clusters can lower the transition energies associated with the dominant electronic transitions quite significantly thereby enabling the metal cluster supported BNF moieties to exhibit significant non-linear optical activity. Moreover, the studied systems demonstrate broad band absorption capability spanning the UV-visible as well as infra-red domains. Energy decomposition analysis reveals that the electrostatic interactions principally stabilize the metal cluster supported BNF moieties.

  16. Some Biochemical Effects Of a Mainly Fruit Diet In Man | Meyer ...

    African Journals Online (AJOL)

    The effect of a nut-supplemented fruit diet on glucose tolerance, insulin secretion, plasma proteins and plasma lipids of human volunteers was investigated. The results suggest that, at least for the period covered by the experiment and under the prevailing conditions, the diet was adequate with respect to the parameters ...

  17. FEM Computations Concerning the Effect of Friction in Two LHC Main Dipole Structures

    CERN Document Server

    Bajko, M; Perini, D

    2000-01-01

    The mechanical behaviour of a dipole structure is considered when also friction is taken into account, studying its effect on different components and in different conditions. In particular the difference in behavior between a structure with aluminium collars and one with austenitic steel ones was studied.

  18. On long-term effects of the Chernobyl accident in the German Federal main waterways

    International Nuclear Information System (INIS)

    Mundschenk, H.

    1992-01-01

    The long-term effects are demonstrated (CS-137) and the expected radiation exposure on the pathways 'drinking water' and 'spoil field' for rather conservative assumptions estimated. The aim of the measurements performed is explained in detail and the interpretation problems of various sediment data discussed thoroughly. (orig./HP) [de

  19. Impact of Maine's Medicaid drug formulary change on non-Medicaid markets: spillover effects of a restrictive drug formulary.

    Science.gov (United States)

    Wang, Y Richard; Pauly, Mark V; Lin, Y Aileen

    2003-10-01

    Market penetration of HMOs affect physician practice styles for non-HMO patients. To study the impact of a restrictive Medicaid drug formulary on prescribing patterns for other patients, ie, so-called spillover effects. A before-and-after, 3-state comparison study. On January 1, 2001, Maine's Medicaid program implemented a restrictive drug formulary for the proton pump inhibitor class, with pantoprazole as the only preferred drug. The Medicaid and non-Medicaid market shares of pantoprazole in Maine (vs New Hampshire and Vermont and among Maine physicians with different Medicaid share of practice. After 3 months, the market share of pantoprazole in Maine (vs 2 control states) increased 79% among Medicaid prescriptions (vs 1%-2%), 10% among cash prescriptions (vs 3%), and 7% among other third-party payer prescriptions (vs 1%). The market shares increased more among Maine physicians with a higher Medicaid share of practice (high vs middle vs low [market]: 16% vs 8% vs 5% [cash]; 11% vs 5% vs 4% [other third-party payers]). Linear regression results indicate that practicing medicine in Maine leads to a 72% increase in pantoprazole share among Medicaid prescriptions (P markets, with somewhat stronger effects in the cash market.

  20. ASTEC V2 severe accident integral code main features, current V2.0 modelling status, perspectives

    International Nuclear Information System (INIS)

    Chatelard, P.; Reinke, N.; Arndt, S.; Belon, S.; Cantrel, L.; Carenini, L.; Chevalier-Jabet, K.; Cousin, F.; Eckel, J.; Jacq, F.; Marchetto, C.; Mun, C.; Piar, L.

    2014-01-01

    The severe accident integral code ASTEC, jointly developed since almost 20 years by IRSN and GRS, simulates the behaviour of a whole nuclear power plant under severe accident conditions, including severe accident management by engineering systems and procedures. Since 2004, the ASTEC code is progressively becoming the reference European severe accident integral code through in particular the intensification of research activities carried out in the frame of the SARNET European network of excellence. The first version of the new series ASTEC V2 was released in 2009 to about 30 organizations worldwide and in particular to SARNET partners. With respect to the previous V1 series, this new V2 series includes advanced core degradation models (issued from the ICARE2 IRSN mechanistic code) and necessary extensions to be applicable to Gen. III reactor designs, notably a description of the core catcher component to simulate severe accidents transients applied to the EPR reactor. Besides these two key-evolutions, most of the other physical modules have also been improved and ASTEC V2 is now coupled to the SUNSET statistical tool to make easier the uncertainty and sensitivity analyses. The ASTEC models are today at the state of the art (in particular fission product models with respect to source term evaluation), except for quenching of a severely damage core. Beyond the need to develop an adequate model for the reflooding of a degraded core, the main other mean-term objectives are to further progress on the on-going extension of the scope of application to BWR and CANDU reactors, to spent fuel pool accidents as well as to accidents in both the ITER Fusion facility and Gen. IV reactors (in priority on sodium-cooled fast reactors) while making ASTEC evolving towards a severe accident simulator constitutes the main long-term objective. This paper presents the status of the ASTEC V2 versions, focussing on the description of V2.0 models for water-cooled nuclear plants

  1. Main directions of providing of industrial enterprises effective development and conditions of their choice

    Directory of Open Access Journals (Sweden)

    Y. V. Zhuravlev

    2016-01-01

    Full Text Available Difficulties in managing the effective development of an industrial enterprise is largely due to the lack of complex tools to measure it, which is aggravated by the lack of identification of the factors that affect the food industry enterprises. In the article, we investigated directions of providing of industrial enterprises effective development and determined conditions of their choice depending on organizational assets and enterprise’s added value dynamics. For every possible combination, we offered certain mechanism of effective development: internal – by means of enterprise’s self-potential activation, and external – by means of deep, moderate or shallow integration. Deep integration means full merger of the enterprise and is recommended in case of critical level of enterprise’s potential. Moderate integration is implemented by purchase of controlling block of shares and is carried out in case of critical or high enterprise’s potential combined with growth of added value. Shallow integration can be used in any combination of resources and added value and is implemented on a contractual basis without institutional and legal change. The concept of directions of providing of industrial enterprises development, that we worked out, is of applicable character and can be used by industrial enterprises regardless field and specific character of industry. Implementation of offered measures will provide industrial enterprises effective development, which will help to form organizational assets base of Russian economics, which is a powerful driver of modernization of Russian industrial enterprises and economics as a whole.

  2. The effects of storms and storm-generated currents on sand beaches in Southern Maine, USA

    Science.gov (United States)

    Hill, H.W.; Kelley, J.T.; Belknap, D.F.; Dickson, S.M.

    2004-01-01

    Storms are one of the most important controls on the cycle of erosion and accretion on beaches. Current meters placed in shoreface locations of Saco Bay and Wells Embayment, ME, recorded bottom currents during the winter months of 2000 and 2001, while teams of volunteers profiled the topography of nearby beaches. Coupling offshore meteorological and beach profile data made it possible to determine the response of nine beaches in southern Maine to various oceanographic and meteorological conditions. The beaches selected for profiling ranged from pristine to completely developed and permitted further examination of the role of seawalls on the response of beaches to storms. Current meters documented three unique types of storms: frontal passages, southwest storms, and northeast storms. In general, the current meter results indicate that frontal passages and southwest storms were responsible for bringing sediment towards the shore, while northeast storms resulted in a net movement of sediment away from the beach. During the 1999-2000 winter, there were a greater percentage of frontal passages and southwest storms, while during the 2000-2001 winter, there were more northeast storms. The sediment that was transported landward during the 1999-2000 winter was reworked into the berm along moderately and highly developed beaches during the next summer. A northeast storm on March 5-6, 2001, resulted in currents in excess of 1 m s-1 and wave heights that reached six meters. The storm persisted over 10 high tides and caused coastal flooding and property damage. Topographic profiles made before and after the storm demonstrate that developed beaches experienced a loss of sediment volume during the storm, while sediment was redistributed along the profile on moderately developed and undeveloped beaches. Two months after the storm, the profiles along the developed beaches had not reached their pre-storm elevation. In comparison, the moderately developed and undeveloped beaches

  3. [The workplace-based learning: a main paradigm of an effective continuing medical education].

    Science.gov (United States)

    Lelli, Maria Barbara

    2010-01-01

    On the strength of the literature analysis and the Emilia-Romagna Region experience, we suggest a reflection on the workplace-based learning that goes beyond the analysis of the effectiveness of specific didactic methodologies and aspects related to Continuing Medical Education. Health education and training issue is viewed from a wider perspective, that integrates the three learning dimensions (formal, non formal and informal). In such a perspective the workplace-based learning becomes an essential paradigm to reshape the explicit knowledge conveyed in formal context and to emphasize informal contexts where innovation is generated.

  4. Main pumps lost incident in the nuclear power plant Atucha I. Modelling with RELAP5/MOD3.2

    International Nuclear Information System (INIS)

    Ventura, M.A.; Rosso, R.D.

    1998-01-01

    Time evolution of natural circulation in the nuclear power plant Atucha I (CNA-I), in a main pumps lost incident because of the lost of external power feed, is analyzed. It leads to a strong stop transient, without an important blow down, from a forced nominal flow to a natural circulation one. The results are obtained from RELAP5/MOD3.2 code's modeling. The study is based on the refrigeration conditions analysis, during the first minutes of the reactor out of service. Previously to the transient, work had been done to obtain the plant steady state, with design parameters in operation conditions at 100 % of power. The object is that the actual plant state would be represented. In this way, each plant part (steam generators, reactor, pressurizer, pumps) had been modeled in separated form with the appropriate boundary conditions, to be used in the whole circuit simulation. The developed model, had been validated making use of the comparison between the values obtained to the principal thermodynamic parameters with the plant recorded values, in the same incident. The results are satisfactory in a way. On the other hand, it has suggested some modeling changes. The RELAP5/MOD3.2 capability to model the thermodynamic phenomena in a PHWR plant has been verified when, according to the mentioned incident, the flow pass from a nominal forced flow, to one which is governed by natural circulation, still with the CNA-I untypical design conditions. (author) [es

  5. Investigation of the 2006 Alexandrium fundyense Bloom in the Gulf of Maine: In situ Observations and Numerical Modeling.

    Science.gov (United States)

    Li, Yizhen; He, Ruoying; McGillicuddy, Dennis J; Anderson, Donald M; Keafer, Bruce A

    2009-09-30

    In situ observations and a coupled bio-physical model were used to study the germination, initiation, and development of the Gulf of Maine (GOM) Alexandrium fundyense bloom in 2006. Hydrographic measurements and comparisons with GOM climatology indicate that 2006 was a year with normal coastal water temperature, salinity, current and river runoff conditions. A. fundyense cyst abundance in bottom sediments preceding the 2006 bloom was at a moderate level compared to other recent annual cyst survey data. We used the coupled bio-physical model to hindcast coastal circulation and A. fundyense cell concentrations. Field data including water temperature, salinity, velocity time series and surface A. fundyense cell concentration maps were applied to gauge the model's fidelity. The coupled model is capable of reproducing the hydrodynamics and the temporal and spatial distributions of A. fundyense cell concentration reasonably well. Model hindcast solutions were further used to diagnose physical and biological factors controlling the bloom dynamics. Surface wind fields modulated the bloom's horizontal and vertical distribution. The initial cyst distribution was found to be the dominant factor affecting the severity and the interannual variability of the A. fundyense bloom. Initial cyst abundance for the 2006 bloom was about 50% of that prior to the 2005 bloom. As the result, the time-averaged gulf-wide cell concentration in 2006 was also only about 60% of that in 2005. In addition, weaker alongshore currents and episodic upwelling-favorable winds in 2006 reduced the spatial extent of the bloom as compared with 2005.

  6. 2D and 3D Models of Convective Turbulence and Oscillations in Intermediate-Mass Main-Sequence Stars

    Science.gov (United States)

    Guzik, Joyce Ann; Morgan, Taylor H.; Nelson, Nicholas J.; Lovekin, Catherine; Kitiashvili, Irina N.; Mansour, Nagi N.; Kosovichev, Alexander

    2015-08-01

    We present multidimensional modeling of convection and oscillations in main-sequence stars somewhat more massive than the sun, using three separate approaches: 1) Applying the spherical 3D MHD ASH (Anelastic Spherical Harmonics) code to simulate the core convection and radiative zone. Our goal is to determine whether core convection can excite low-frequency gravity modes, and thereby explain the presence of low frequencies for some hybrid gamma Dor/delta Sct variables for which the envelope convection zone is too shallow for the convective blocking mechanism to drive g modes; 2) Using the 3D planar ‘StellarBox’ radiation hydrodynamics code to model the envelope convection zone and part of the radiative zone. Our goals are to examine the interaction of stellar pulsations with turbulent convection in the envelope, excitation of acoustic modes, and the role of convective overshooting; 3) Applying the ROTORC 2D stellar evolution and dynamics code to calculate evolution with a variety of initial rotation rates and extents of core convective overshooting. The nonradial adiabatic pulsation frequencies of these nonspherical models will be calculated using the 2D pulsation code NRO of Clement. We will present new insights into gamma Dor and delta Sct pulsations gained by multidimensional modeling compared to 1D model expectations.

  7. Towards a new generation of flow and transport models for the Aespoe Hard Rock Laboratory. Main results from the project Aespoe models 2005

    International Nuclear Information System (INIS)

    Svensson, Urban; Vidstrand, Patrik; Neretnieks, Ivars; Wallin, Bill

    2008-05-01

    This report constitutes the outcome of a project called 'Aespoe models 2005'. The main objective of the project has been to provide a first step towards a new generation of numerical models of flow and transport, for the Aespoe HRL. In order to achieve this goal, work has been carried out along three parallel lines; discussion of basic concepts, compilation and analysis of data and model applications. A number of sub tasks are reported as appendices in the report. In fact, these appendices represent the main achievements of the project: an analysis of fracture properties, compilation of isotope and chemical data, dispersion and mixing in fractured rocks and model results. The conclusion of the project is that significant contributions to a new generation of Aespoe models have been obtained. It has further been demonstrated that working numerical simulations are up and running. Recommendations are provided for the continued work

  8. Towards a new generation of flow and transport models for the Aespoe Hard Rock Laboratory. Main results from the project Aespoe models 2005

    Energy Technology Data Exchange (ETDEWEB)

    Svensson, Urban (ed.) (Computer-aided Fluid Engineering AB (CFE AB), SE-602 10 Norrkoeping (Sweden)); Vidstrand, Patrik (Bergab AB, Goeteborg (Sweden)); Neretnieks, Ivars (Dept. of Chemical Engineering and Technology, Royal Inst. of Technology, Stockholm (Sweden)); Wallin, Bill (Geokema, Lidingoe (Sweden))

    2008-05-15

    This report constitutes the outcome of a project called 'Aespoe models 2005'. The main objective of the project has been to provide a first step towards a new generation of numerical models of flow and transport, for the Aespoe HRL. In order to achieve this goal, work has been carried out along three parallel lines; discussion of basic concepts, compilation and analysis of data and model applications. A number of sub tasks are reported as appendices in the report. In fact, these appendices represent the main achievements of the project: an analysis of fracture properties, compilation of isotope and chemical data, dispersion and mixing in fractured rocks and model results. The conclusion of the project is that significant contributions to a new generation of Aespoe models have been obtained. It has further been demonstrated that working numerical simulations are up and running. Recommendations are provided for the continued work

  9. Evaluation of main control room habitability in Japanese LWR (2). Evaluation for applicability of existing atmospheric dispersion models to building wake dispersion by using wind tunnel experiment

    International Nuclear Information System (INIS)

    Fukuda, Ryo; Fujita, Yuko; Yoneda, Jiro; Okabayashi, Kazuki; Tabuse, Shigehiko; Watada, Masayuki

    2009-01-01

    It is necessary to predict the concentration field behind the containment vessel building for the evaluation of main control room habitability in case of the emergency. The concentration field behind the building is very complicated phenomena and the exact prediction of concentration would be very difficult even if philosophical numerical simulation was used. Instead the simple and analytical prediction models (ARCON96, Gifford and Murphy-Campe etc.) have been used for the assessment of main control room habitability. In order to evaluate the previous models, the wind tunnel experiment was carried out. Recent regulatory models of ADMS4 developed by UK-CERC and AERMOD by US-EPA were also compared with this experimental data. Only both the containment vessel and reactor buildings of the typical PWR plant was scaled in 1/200 and the atmospheric stability C-D between C and D of Pasquill-Gifford categories was reproduced as a neutral condition in the wind tunnel experiment. In the wind experiment, the meandering effect for 1 hour was taken into consideration by the so-called overlapping method that a scaled model in the test section of a wind tunnel was rotated. By the rotation of the scaled model, wind directional fluctuations were relatively generated in the test section. The model was rotated at a various speed which was inversely proportional to each frequency of occurrence of a wind direction. Tracer gas was sampled during the rotation of the building model. As a result, we got the 1 hr.-averaged concentration taking a meandering effect into consideration. In this experiment, it is assumed that the frequency distribution of wind direction is Gaussian and horizontal plume width for 1 hr. was expanded to about 1.8 times of plume width based on Pasquill-Gifford chart by 1/5 power law due to the meandering effect. From the experiment, it was found as follows; It seems that meandering effect was not important in the near field behind a building, because strong

  10. Effect of a venotonic agent on the main arteries and veins during a 5 day HDT

    Science.gov (United States)

    Roumy, Jerome; Herault, Stephane; Tobal, Nathalie; Besnard, Stephane; Arbeille, Philippe

    2001-08-01

    Objective: To evaluate the cardiac, arterial and venous effect of a venotonic drug (Cirkan « Ck å) administrated orally daily to 6 subjects in HDT position during 5 days. These subjects underwent a second 5d HDT without Ck treatment one month later. Pre and post HDT the subjects were submitted to a stand test. Method: The cardiovascular parameters were measured by echography and Doppler. Results and discussion: The Cirkan treatment contributed to reduce the increase in cerebral resistance, and to maintain the lower limb resistance at a higher level than on controls. It reduces the vein section at the extremities (Jugular, femoral) and in the central vein system connected to the right heart (sub hepatics). On the other hand it increases the portal vein section which means that the blood stagnation at the splanchnic level is increased. Despite these arterial and venous significant modifications the clinical and ECG and Blood pressure response to the Stand test was similar in both groups.

  11. Leading change: a three-dimensional model of nurse leaders' main tasks and roles during a change process.

    Science.gov (United States)

    Salmela, Susanne; Eriksson, Katie; Fagerström, Lisbeth

    2012-02-01

    This paper is a report of a qualitative study which explored how nurse leaders described and understood their main tasks and roles during a change process. During a database search for literature, no actual research that highlighted the main tasks and roles of nurse leaders during a change process was found. Earlier research has indicated the need for different leadership styles and the importance of strategies and values. In-depth interviews with 17 nurse leaders took place in 2004. A phenomenological-hermeneutical approach was used for data analysis. The findings resulted in a model of leading change in health care that focuses on good patient care and consists of three dimensions: leading relationships, leading processes and leading a culture. In addition to leading relationships and processes, nurse leaders, as role models, greatly impact caring culture and its inherent ethical behaviour, especially about the responsibility for achieving good patient care. Nurse leaders are also instrumental in leading ward culture. Nurse leaders need guidance and knowledge of what is expected of them during a structural change process. They play different roles by directing, guiding, motivating, supporting and communicating without losing their cultural ethos of caring and use various leadership styles to bring about actual change, which, in turn, requires learning so that the thought patterns, values and attitudes of personnel can be changed. © 2011 Blackwell Publishing Ltd.

  12. Dopaminergic, Serotonergic, and Oxytonergic Candidate Genes Associated with Infant Attachment Security and Disorganization? In Search of Main and Interaction Effects

    Science.gov (United States)

    Luijk, Maartje P. C. M.; Roisman, Glenn I.; Haltigan, John D.; Tiemeier, Henning; Booth-LaForce, Cathryn; van IJzendoorn, Marinus H.; Belsky, Jay; Uitterlinden, Andre G.; Jaddoe, Vincent W. V.; Hofman, Albert; Verhulst, Frank C.; Tharner, Anne; Bakermans-Kranenburg, Marian J.

    2011-01-01

    Background and methods: In two birth cohort studies with genetic, sensitive parenting, and attachment data of more than 1,000 infants in total, we tested main and interaction effects of candidate genes involved in the dopamine, serotonin, and oxytocin systems ("DRD4", "DRD2", "COMT", "5-HTT", "OXTR") on attachment security and disorganization.…

  13. Application of the reliability theory on the analysis of the effects of sbwr' main control console maintenance

    International Nuclear Information System (INIS)

    Widagdo, S.

    1997-01-01

    Maintenance activities on the main control console, which is a primary element of the man-machine interface system, are a source of concern. this concern has been arisen since the main control function is the central part to observe and control the reactor operation. the paper will discuss a study of the effects of main control console maintenance activity upon the operability of SBWR. the first step is learning the SBWR main control room design in order to know its monitoring and controlling capability and then makes an assumption of maintenance requirement followed by an evaluation of the effects of the maintenance activity. it is assumed that 2 years or equivalent to 17.520 hours are the reference time for one cycle operation of SBWR. the aim is to identify any adverse effects and eliminate or minimize them through design improvements. the evaluation method used here is the reability theory R(t) = e sup-λt. Based on the result of the evaluation can be concluded that there are no negative effects of maintenance activity upon the operability of the SBWR

  14. Studing the Influence of Six Main Industrial Losses on Overall Equipment Effectiveness in Cold Rolling Unit of Mobarakeh Steel Complex

    Directory of Open Access Journals (Sweden)

    seyed Akbar Nilipour Tabatabaei

    2011-03-01

    Full Text Available Overall Equipment Effectiveness (OEE is a key indicator and a basis for evaluating the effectiveness of equipments as well as assessing the effectiveness of the Total Productive Maintenance (TPM system. This indicator together with overall equipment performance can be used in production lines such as steel production. The aim of this article is to study the influence of six main industrial losses on the OEE indicator . For this purpose, the OEE has been calculated in the cold rolling production lines of Mobarakeh Steel Complex the gap between production lines and the global industrial standards has been studied the causes of production system inefficiency has been investigated and the effectiveness of TPM system, equipments' bottlenecks and the influence of the main industry losses on OEE have been studied. The findings imply that the influence of the variation of availability and performance rates on OEE is high, while the influence of the variation of quality rate on OEE is not considerable.

  15. MAIN ABSTRACTS

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    Reflection on Some Issues Regarding the System of Socialism with Chinese Characteristics Zhang Xingmao The establishment of the system of socialism with Chinese characteristics, as the symbol of China's entry into the socialist society with Chinese characteristics, is the significant development of Marist theory of social formation. The Chinese model is framed and defined by the socialist system with Chinese characteristics, therefore the study of different levels and aspects of the Chinese model should be related to the relevant Chinese system to guarantee a scientific interpretation. Under the fundamental system of socialism, the historical and logical starting point of the formation of socialism with Chinese characteristics lies in eliminating the private ownership first and then allowing the existence and rapid development of the non-public sectors of the economy. With the gradual establishment and on the basis of the basic economic system in the preliminary stage of Socialism, and with the adaptive adjustments in the economic, political, cultural, and social systems, the socialist system with Chinese characteristics is gradually formed.

  16. The ability of general circulation models to simulate tropical cyclones and their precursors over the North Atlantic main development region

    Energy Technology Data Exchange (ETDEWEB)

    Daloz, Anne Sophie; Chauvin, Fabrice [Groupe de Modelisation Grande Echelle et Climat, CNRM-GAME, Meteo-France, Toulouse Cedex 1 (France); Walsh, Kevin [University of Melbourne, School of Earth Sciences, Melbourne, VIC (Australia); Lavender, Sally; Abbs, Deborah [CSIRO Atmospheric and Marine Research, Aspendale, VIC (Australia); Roux, Frank [Universite de Toulouse and Centre National de la Recherche Scientifique, Laboratoire d' Aerologie, Toulouse (France)

    2012-10-15

    The ability of General Circulation Models (GCMs) to generate Tropical Cyclones (TCs) over the North Atlantic Main Development Region (MDR; 10-20 N, 20-80 W; Goldenberg and Shapiro in J Clim 9:1169-1187, 1996) is examined through a subset of ocean-atmosphere coupled simulations from the World Climate Research Programme (WCRP) Coupled Model Intercomparison Project phase 3 (CMIP3) multimodel data set and a high-resolution (0.5 ) Sea Surface Temperature (SST)-forced simulation from the Australian Conformal-Cubic Atmospheric Model GCM. The results are compared with National Center for Environmental Prediction (NCEP-2) and European Center for Medium Range Weather Forecasts Re-Analysis (ERA-40) reanalyses over a common period from 1980 to 1998. Important biases in the representation of the TC activity are encountered over the MDR. This study emphasizes the strong link in the GCMs between African Easterly Waves (AEWs) and TC activity in this region. However, the generation of AEWs is not a sufficient condition alone for the models to produce TCs. Precipitation over the Sahel, especially rainfall over the Fouta Djallon highlands (cf. Fig. 1), is playing a role in the generation of TCs over the MDR. The influence of large-scale fields such as SST, vertical wind shear and tropospheric humidity on TC genesis is also examined. The ability of TC genesis indices, such as the Genesis Potential Index and the Convective Yearly Genesis Potential, to represent TC activity over the MDR in simulations at low to high spatial resolutions is analysed. These indices are found to be a reasonable method for comparing cyclogenesis in different models, even though other factors such as AEW activity should also be considered. (orig.)

  17. Studies and analyses of the space shuttle main engine. Failure information propagation model data base and software

    Science.gov (United States)

    Tischer, A. E.

    1987-01-01

    The failure information propagation model (FIPM) data base was developed to store and manipulate the large amount of information anticipated for the various Space Shuttle Main Engine (SSME) FIPMs. The organization and structure of the FIPM data base is described, including a summary of the data fields and key attributes associated with each FIPM data file. The menu-driven software developed to facilitate and control the entry, modification, and listing of data base records is also discussed. The transfer of the FIPM data base and software to the NASA Marshall Space Flight Center is described. Complete listings of all of the data base definition commands and software procedures are included in the appendixes.

  18. Effects of CYP2C19 polymorphism on the pharmacokinetics of lansoprazole and its main metabolites in healthy Chinese subjects.

    Science.gov (United States)

    Zhang, Dan; Wang, Xiaolin; Yang, Man; Wang, Guocai; Liu, Huichen

    2011-06-01

    The aim of the study was to determine the pharmacokinetics of lansoprazole and its main metabolites (5'-hydroxy lansoprazole and lansoprazole sulphone) after administration of enteric-coated tablet in healthy Chinese subjects classified by CYP2C19 genotypes, and evaluate the effects of CYP2C19 genotypes on the pharmacokinetics of the three compounds. A single oral dose of 30 mg lansoprazole was administrated to 24 healthy Chinese male volunteers in different CYP2C19 genotype groups. Blood samples were collected from pre-dose up to 14-h post-dose. Plasma concentration of lansoprazole and its main metabolites were quantified by liquid chromatography-tandem mass spectrometry. CYP2C19 polymorphism had significant effects on the pharmacokinetics of lansoprazole and its main metabolites. The differences in the pharmacokinetics between CYP2C19 extensive metabolizers (Ems) (homo-EMs and hete-EMs) and PMs were more significant for lansoprazole sulphone than for 5'-hydroxy lansoprazole. The results indicate that the monitoring of lansoprazole and its main metabolites in plasma at the time-points in the elimination phase for lansoprazole could reflect the activity of CYP2C19. Simultaneously monitored with lansoprazole sulphone, lansoprazole might be a useful probe drug for CYP2C19.

  19. Training effectiveness evaluation model

    International Nuclear Information System (INIS)

    Penrose, J.B.

    1993-01-01

    NAESCO's Training Effectiveness Evaluation Model (TEEM) integrates existing evaluation procedures with new procedures. The new procedures are designed to measure training impact on organizational productivity. TEEM seeks to enhance organizational productivity through proactive training focused on operation results. These results can be identified and measured by establishing and tracking performance indicators. Relating training to organizational productivity is not easy. TEEM is a team process. It offers strategies to assess more effectively organizational costs and benefits of training. TEEM is one organization's attempt to refine, manage and extend its training evaluation program

  20. The Missing Main Effect of Welfare State Regimes: A Replication of ‘Social Policy Responsiveness in Developed Democracies’ by Brooks and Manza

    Directory of Open Access Journals (Sweden)

    Nate Breznau

    2015-08-01

    Full Text Available This article reports the results of a replication of Brooks and Manza's "Social Policy Responsiveness in Developed Democracies" published in 2006 in the American Sociological Review. The article finds that Brooks and Manza utilized an interaction term but excluded the main effect of one of the interacted variables. This model specification has specific implications: statistically, that the omitted main effect variable has no correlation with the residual error term from their regression; theoretically speaking, this means that all unobserved historical, cultural, and other characteristics that distinguish liberal democratic welfare regimes from others can be accounted for with a handful of quantitative measures. Using replicated data, this article finds that the Brooks and Manza models fail these assumptions. A sensitivity analysis using more than 800 regressions with different configurations of variables confirms this. In 99.5 percent of the cases, addition of the main effect removes Brooks and Manza's empirical findings completely. A theoretical discussion illuminates why these findings are not surprising. This article provides a reminder that models and theories are coterminous, each implied by the other.

  1. Ecotoxicological effects extrapolation models

    Energy Technology Data Exchange (ETDEWEB)

    Suter, G.W. II

    1996-09-01

    One of the central problems of ecological risk assessment is modeling the relationship between test endpoints (numerical summaries of the results of toxicity tests) and assessment endpoints (formal expressions of the properties of the environment that are to be protected). For example, one may wish to estimate the reduction in species richness of fishes in a stream reach exposed to an effluent and have only a fathead minnow 96 hr LC50 as an effects metric. The problem is to extrapolate from what is known (the fathead minnow LC50) to what matters to the decision maker, the loss of fish species. Models used for this purpose may be termed Effects Extrapolation Models (EEMs) or Activity-Activity Relationships (AARs), by analogy to Structure-Activity Relationships (SARs). These models have been previously reviewed in Ch. 7 and 9 of and by an OECD workshop. This paper updates those reviews and attempts to further clarify the issues involved in the development and use of EEMs. Although there is some overlap, this paper does not repeat those reviews and the reader is referred to the previous reviews for a more complete historical perspective, and for treatment of additional extrapolation issues.

  2. The effects of precipitation, river discharge, land use and coastal circulation on water quality in coastal Maine.

    Science.gov (United States)

    Tilburg, Charles E; Jordan, Linda M; Carlson, Amy E; Zeeman, Stephan I; Yund, Philip O

    2015-07-01

    Faecal pollution in stormwater, wastewater and direct run-off can carry zoonotic pathogens to streams, rivers and the ocean, reduce water quality, and affect both recreational and commercial fishing areas of the coastal ocean. Typically, the closure of beaches and commercial fishing areas is governed by the testing for the presence of faecal bacteria, which requires an 18-24 h period for sample incubation. As water quality can change during this testing period, the need for accurate and timely predictions of coastal water quality has become acute. In this study, we: (i) examine the relationship between water quality, precipitation and river discharge at several locations within the Gulf of Maine, and (ii) use multiple linear regression models based on readily obtainable hydrometeorological measurements to predict water quality events at five coastal locations. Analysis of a 12 year dataset revealed that high river discharge and/or precipitation events can lead to reduced water quality; however, the use of only these two parameters to predict water quality can result in a number of errors. Analysis of a higher frequency, 2 year study using multiple linear regression models revealed that precipitation, salinity, river discharge, winds, seasonality and coastal circulation correlate with variations in water quality. Although there has been extensive development of regression models for freshwater, this is one of the first attempts to create a mechanistic model to predict water quality in coastal marine waters. Model performance is similar to that of efforts in other regions, which have incorporated models into water resource managers' decisions, indicating that the use of a mechanistic model in coastal Maine is feasible.

  3. Main types of environmental pollution the contributory causes, the effects on environment and the suggested remedial measures

    International Nuclear Information System (INIS)

    Hussain, M.

    1995-01-01

    In this article the main types of environmental pollution, the contributory causes, the effects on environment and suggested remedial measures have been described. The fundamental types of environmental pollution are land pollution, water pollution and air pollution. Many artificial and natural factors contribute towards land pollution. Several remedial measures have suggested in this article, some of them are provision of clean water by municipal agencies, toxic wastes or nuclear wastes should not disposed off in the sea. (A.B.)

  4. Modeling and Analysis of Queuing Systems in Banks A case study of Ghana Commercial Bank Ltd. Kumasi Main Branch

    Directory of Open Access Journals (Sweden)

    Wallace Agyei

    2015-07-01

    Full Text Available Abstract Queues are common sight of many banks in Ghana. The obvious implication of customers waiting in long and winding queues could result to prolonged discomfort and economic cost to them however increasing the service rate will require additional number of tellers which implies extra cost to management. This study therefore attempts to find the trade-off between minimizing the total economic cost waiting cost and service cost and the provision of a satisfactory and reasonably shortest possible time of service to customers in order to assist management of the bank in deciding the optimal number of tellers needed. Data for this study was collected at the Ghana Commercial Bank Ltd Kumasi Main Branch for one month through observations interviews and by administering of questionnaire and was formulated as multi-server single line queuing model. The data was analyzed using TORA optimization Software as well as using descriptive method of analysis. The performance measures of different queuing systems were evaluated and analyzed. The results of the analysis showed using a five teller system was better than a four or a six-teller system in terms of average waiting time and thetotal economic cost hence the study recommends that the management should adopt a five teller model to reduce total economic costs and increase customer satisfaction.

  5. Geophysical modeling of the northern Appalachian Brompton-Cameron, Central Maine, and Avalon terranes under the New Jersey Coastal Plain

    Science.gov (United States)

    Maguire, T.J.; Sheridan, R.E.; Volkert, R.A.

    2004-01-01

    A regional terrane map of the New Jersey Coastal Plain basement was constructed using seismic, drilling, gravity and magnetic data. The Brompton-Cameron and Central Maine terranes were coalesced as one volcanic island arc terrane before obducting onto Laurentian, Grenville age, continental crust in the Taconian orogeny [Rankin, D.W., 1994. Continental margin of the eastern United States: past and present. In: Speed, R.C., (Ed.), Phanerozoic Evolution of North American Continent-Ocean Transitions. DNAG Continent-Ocean Transect Volume. Geological Society of America, Boulder, Colorado, pp. 129-218]. Volcanic island-arc rocks of the Avalon terrane are in contact with Central Maine terrane rocks in southern Connecticut where the latter are overthrust onto the Brompton-Cameron terrane, which is thrust over Laurentian basement. Similarities of these allochthonous island arc terranes (Brompton-Cameron, Central Maine, Avalon) in lithology, fauna and age suggest that they are faulted segments of the margin of one major late Precambrian to early Paleozoic, high latitude peri-Gondwana island arc designated as "Avalonia", which collided with Laurentia in the early to middle Paleozoic. The Brompton Cameron, Central Maine, and Avalon terranes are projected as the basement under the eastern New Jersey Coastal Plain based on drill core samples of metamorphic rocks of active margin/magmatic arc origin. A seismic reflection profile across the New York Bight traces the gentle dipping (approximately 20 degrees) Cameron's Line Taconian suture southeast beneath allochthonous Avalon and other terranes to a 4 sec TWTT depth (approximately 9 km) where the Avalonian rocks are over Laurentian crust. Gentle up-plunge (approximately 5 degrees) projections to the southwest bring the Laurentian Grenville age basement and the drift-stage early Paleozoic cover rocks to windows in Burlington Co. at approximately 1 km depth and Cape May Co. at approximately 2 km depths. The antiformal Shellburne

  6. Ecological niche model of Phlebotomus perniciosus, the main vector of canine leishmaniasis in north-eastern Italy

    Directory of Open Access Journals (Sweden)

    Manuela Signorini

    2014-11-01

    Full Text Available With respect to the epidemiology of leishmaniasis, it is crucial to take into account the ecoclimatic and environ- mental characteristics that influence the distribution patterns of the vector sand fly species. It is also important to consider the possible impact of on-going climate changes on the emergence of this disease. In order to map the potential distribu- tion of Phlebotomus perniciosus, the main vector species of canine leishmaniasis in north-eastern Italy, geographical information systems tools, ecological niche models (ENM and remotely sensed environmental data were applied for a retrospective analysis of an entomological survey conducted in north-eastern Italy over 12 years. Sand fly trapping was conducted from 2001 to 2012 in 175 sites in the provinces of Veneto, Friuli-Venezia Giulia and Trentino-Alto Adige. We developed a predictive model of potential distribution of P. perniciosus using the maximum entropy algorithm software, based on seasonal normalized difference vegetation index, day and night land surface temperature, the Corine land cover 2006, a digital elevation model (GTOPO30 and climate layers obtained from the WorldClim database. The MaxEnt pre- diction found the more suitable habitat for P. perniciosus to be hilly areas (100-300 m above the mean sea level charac- terised by temperate climate during the winter and summer seasons, high winter vegetation cover and moderate rainfall during the activity season of vector sand fly. ENM provided a greater understanding of the geographical distribution and ecological requirements of P. perniciosus in the study area, which can be applied for the development of future surveil- lance strategies.

  7. [Effect of air pollution on respiratory health in school-aged children in the main urban area of Chongqing, China].

    Science.gov (United States)

    Fan, Ming-Yue; Tang, Xu; Huang, Wei; Dai, Hua; Liu, Xing-Can; Xia, Yin-Yin; Meng, Pan; Zhang, Rui-Yuan; Guo, Yu-Ming; Cheng, Shu-Qun

    2017-04-01

    To investigate the effect of air pollution on respiratory health in school-aged children in the main urban area of Chongqing, China. The main urban area of Chongqing was divided into polluted area and clean area according to the air pollution data shown on the Environmental Protection Agency Website of Chongqing between 2010 and 2015. A cluster sampling method was used to select 695 third- or fourth-grade children from 2 primary schools in the clean or polluted area as study subjects, with 313 children from the clean area and 382 children from the polluted area. Pulmonary function was examined for all children and a standard American epidemiological questionnaire (ATS-DLD-78-C) was used to investigate the prevalence of respiratory diseases and symptoms. Compared with the clean area, the polluted area had significantly higher concentrations of inhalable particles (PM 10 ), fine particulate matter (PM 2.5 ), and nitric oxide (NO X ) (Ppolluted area had significantly higher risks of cough (OR=1.644), cough during cold (OR=1.596), expectoration during cold (OR=2.196), persistent expectoration (OR=1.802), and wheezing (OR=2.415). The boys and girls in the clean area had significantly higher forced vital capacity and forced expiratory volume in one second than those in the polluted area (PAir pollution in the main urban area of Chongqing is associated with the increased prevalence of respiratory symptoms in school-aged children and has certain effect on children's pulmonary function.

  8. Main Geomagnetic Field Models from Oersted and Magsat Data Via a Rigorous General Inverse Theory with Error Bounds

    Science.gov (United States)

    Backus, George E.

    1999-01-01

    The purpose of the grant was to study how prior information about the geomagnetic field can be used to interpret surface and satellite magnetic measurements, to generate quantitative descriptions of prior information that might be so used, and to use this prior information to obtain from satellite data a model of the core field with statistically justifiable error estimates. The need for prior information in geophysical inversion has long been recognized. Data sets are finite, and faithful descriptions of aspects of the earth almost always require infinite-dimensional model spaces. By themselves, the data can confine the correct earth model only to an infinite-dimensional subset of the model space. Earth properties other than direct functions of the observed data cannot be estimated from those data without prior information about the earth. Prior information is based on what the observer already knows before the data become available. Such information can be "hard" or "soft". Hard information is a belief that the real earth must lie in some known region of model space. For example, the total ohmic dissipation in the core is probably less that the total observed geothermal heat flow out of the earth's surface. (In principle, ohmic heat in the core can be recaptured to help drive the dynamo, but this effect is probably small.) "Soft" information is a probability distribution on the model space, a distribution that the observer accepts as a quantitative description of her/his beliefs about the earth. The probability distribution can be a subjective prior in the sense of Bayes or the objective result of a statistical study of previous data or relevant theories.

  9. Vimang (Mangifera indica L. extract) induces permeability transition in isolated mitochondria, closely reproducing the effect of mangiferin, Vimang's main component.

    Science.gov (United States)

    Pardo-Andreu, Gilberto L; Dorta, Daniel Junqueira; Delgado, René; Cavalheiro, Renata A; Santos, Antonio C; Vercesi, Anibal E; Curti, Carlos

    2006-02-01

    Mitochondrial permeability transition (MPT) is a Ca(2+)-dependent, cyclosporin A (CsA)-sensitive, non-selective inner membrane permeabilization process. It is often associated with apoptotic cell death, and is induced by a wide range of agents or conditions, usually involving reactive oxygen species (ROS). In this study, we demonstrated that Mangifera indica L. extract (Vimang), in the presence of 20 microM Ca(2+), induces MPT in isolated rat liver mitochondria, assessed as CsA-sensitive mitochondrial swelling, closely reproducing the same effect of mangiferin, the main component of the extract, as well as MPT-linked processes like oxidation of membrane protein thiols, mitochondrial membrane potential dissipation and Ca(2+) release from organelles. The flavonoid catechin, the second main component of Vimang, also induces MPT, although to a lesser extent; the minor, but still representative Vimang extract components, gallic and benzoic acids, show respectively, low and high MPT inducing abilities. Nevertheless, following exposure to H(2)O(2)/horseradish peroxidase, the visible spectra of these compounds does not present the same changes previously reported for mangiferin. It is concluded that Vimang-induced MPT closely reproduces mangiferin effects, and proposed that this xanthone is the main agent responsible for the extract's MPT inducing ability, by the action on mitochondrial membrane protein thiols of products arising as a consequence of the mangiferin's antioxidant activity. While this effect would oppose the beneficial effect of Vimang's antioxidant activity, it could nevertheless benefit cells exposed to over-production of ROS as occurring in cancer cells, in which triggering of MPT-mediated apoptosis may represent an important defense mechanism to their host.

  10. Development of staffing evaluation principle for advanced main control room and the effect on situation awareness and mental workload

    International Nuclear Information System (INIS)

    Lin, Chiuhsiang Joe; Hsieh, Tsung-Ling; Lin, Shiau-Feng

    2013-01-01

    Highlights: • A staffing evaluation principle was developed for the advanced main control room. • The principle proposed to improve situation awareness and mental workload. • The principle has good validity that was examined by experimental design. - Abstract: Situation awareness and mental workload, both of which influence operator performance in the advanced main control room of a nuclear power plant, can be affected by staffing level. The key goal of staffing is to ensure the proper number of personnel to support plant operations and events. If the staffing level is not adaptive, the operators may have low situation awareness and an excessive mental workload, which lead to human error. Accordingly, this study developed a staffing evaluation principle based on CPM-GOMS modeling for operations in the advanced main control room. A within-subject experiment was designed to examine the validity of the staffing evaluation principle. The results indicated that the situation awareness, mental workload, and operating performance of the staffing level determined by the staffing evaluation principle was significantly better than that of the non-evaluated staffing level; thus, the validity of the staffing evaluation technique is acceptable. The implications of the findings of this study on managerial practice are discussed

  11. Development of staffing evaluation principle for advanced main control room and the effect on situation awareness and mental workload

    Energy Technology Data Exchange (ETDEWEB)

    Lin, Chiuhsiang Joe, E-mail: cjoelin@mail.ntust.edu.tw [Department of Industrial Management, National Taiwan University of Science and Technology, 43, Section 4, Keelung Road, Taipei 10607, Taiwan (China); Hsieh, Tsung-Ling, E-mail: bm1129@gmail.com [Institute of Nuclear Energy Research, 1000, Wenhua Road, Chiaan Village, Lungtan 32546, Taiwan (China); Lin, Shiau-Feng, E-mail: g9602411@cycu.edu.tw [Department of Industrial Engineering, Chung-Yuan Christian University, 200, Chung Pei Road, Chung-Li 32023, Taiwan (China)

    2013-12-15

    Highlights: • A staffing evaluation principle was developed for the advanced main control room. • The principle proposed to improve situation awareness and mental workload. • The principle has good validity that was examined by experimental design. - Abstract: Situation awareness and mental workload, both of which influence operator performance in the advanced main control room of a nuclear power plant, can be affected by staffing level. The key goal of staffing is to ensure the proper number of personnel to support plant operations and events. If the staffing level is not adaptive, the operators may have low situation awareness and an excessive mental workload, which lead to human error. Accordingly, this study developed a staffing evaluation principle based on CPM-GOMS modeling for operations in the advanced main control room. A within-subject experiment was designed to examine the validity of the staffing evaluation principle. The results indicated that the situation awareness, mental workload, and operating performance of the staffing level determined by the staffing evaluation principle was significantly better than that of the non-evaluated staffing level; thus, the validity of the staffing evaluation technique is acceptable. The implications of the findings of this study on managerial practice are discussed.

  12. A study on the evaluation of vibration effect and the development of vibration reduction method for Wolsung unit 1 main steam piping

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Hyun; Kim, Yeon Whan [Korea Electric Power Corp. (KEPCO), Taejon (Korea, Republic of). Research Center; Kim, Tae Ryong; Park, Jin Ho [Korea Atomic Energy Research Inst., Daeduk (Korea, Republic of)

    1996-08-01

    The main steam piping of nuclear power plant which runs between steam generator and high pressure turbine has been experienced to have a severe effect on the safe operation of the plant due to the vibration induced by the steam flowing inside the piping. The imposed cyclic loads by the vibration could result in the degradation of the related structures such as connection parts between main instruments, valves, pipe supports and building. The objective of the study is to reduce the vibration level of Wolsung nuclear power plant unit 1 main steam pipeline by analyzing vibration characteristics of the piping, identifying sources of the vibration and developing a vibration reduction method .The location of the maximum vibration is piping between the main steam header and steam chest .The stress level was found to be within the allowable limit .The main vibration frequency was found to be 4{approx}6 Hz which is the same as the natural frequency from model test .A vibration reduction method using pipe supports of energy absorbing type(WEAR)is selected .The measured vibration level after WEAR installation was reduced about 36{approx}77% in displacement unit (author). 36 refs., 188 figs.

  13. Maine's Employability Skills Program

    Science.gov (United States)

    McMahon, John M.; Wolffe, Karen E.; Wolfe, Judy; Brooker, Carrie

    2013-01-01

    This Practice Report describes the development and implementation of the "Maine Employability Skills Program," a model employment program developed by the Maine Division for the Blind and Visually Impaired (DBVI). The program was designed to support the efforts of the chronically unemployed or underemployed. These consumers were either…

  14. State-of-the-art of wind turbine design codes: main features overview for cost-effective generation

    Energy Technology Data Exchange (ETDEWEB)

    Molenaar, D-P.; Dijkstra, S. [Delft University of Technology (Netherlands). Mechanical Engineering Systems and Control Group

    1999-07-01

    For successful large-scale application of wind energy, the price of electricity generated by wind turbines should decrease. Model-based control can be important since it has the potential to reduce fatigue loads, while simultaneously maintaining a desired amount of energy production. The controller synthesis, however, requires a mathematical model describing the most important dynamics of the complete wind turbine. In the wind energy community there is a wide variety in codes used to model a wind turbine's dynamic behaviour or to carry out design calculations. In this paper, the main features of the state-of-the-art wind turbine design codes have been investigated in order to judge the appropriateness of using one of these for the modeling, identification and control of flexible, variable speed wind turbines. It can be concluded that, although the sophistication of the design codes has increased enormously over the last two decades, they are, in general, not suitable for the design, and easy implementation of optimal operating strategies.

  15. Reactivity of main components and substituent distribution in esterified sugarcane bagasse prepared by effective solid phase reaction.

    Science.gov (United States)

    Gan, Tao; Zhang, Yanjuan; Chen, Yane; Hu, Huayu; Yang, Mei; Huang, Zuqiang; Chen, Dong; Huang, Aimin

    2018-02-01

    Three main components of lignocellulose (cellulose, hemicellulose, and lignin isolated from sugarcane bagasse (SCB)) as well as holocellulose and SCB were modified with maleic acid by mechanical activation (MA)-assisted solid phase reaction (MASPR) technology. The order of reactivity was found to be lignin>hemicellulose>cellulose. The amorphous structure of lignin and hemicellulose mainly attributed to their better reactivity, and the modified lignin could reach a maximum degree of esterification (DE) of 93.45%. MA improved the accessibility and reactivity of cellulose, as the DE of modified cellulose gradually increased with milling time and reached the maximum value of 57.30% at 120min, which had significant effect on structure changes and DE of modified holocellulose and SCB. MA enhanced the esterification of all three components in lignocellulose with relatively high substituent distribution in them, and maleated SCB with a maximum DE of 64.17% was successfully prepared by this simple, green, and effective MASPR technology. Copyright © 2017 Elsevier Ltd. All rights reserved.

  16. Effect of Indigenous Pseudomonas sp. and Bacillus sp. Strains on Yield and Main Chemical Growth Parameters of Radicchio

    Directory of Open Access Journals (Sweden)

    Stanojković-Sebić Aleksandra

    2018-03-01

    Full Text Available Pseudomonas sp. and Bacillus sp. belong to plant growth promoting rhizobacteria which are able to colonize the plants roots and stimulate growth. In this study, the effect of two indigenous plant growth promoting rhizobacterial strains Pseudomonas sp. Q4 and Bacillus sp. Q10 and their mixture (mix Q4+Q10 on content of the main chemical growth parameters (nitrogen, phosphorus, potassium, calcium and magnesium and the yield of dry biomass of radicchio (Cichorium spp. var. rossa di treviso aerial parts and root, was investigated. The study was carried out with stagnosol type of soil in pot experiments under semi-controlled conditions in the Institute of Soil Science (Belgrade, in the period from July to October in 2013. Phosphorus was determined by spectrophotometer, potassium - by flame emission photometry and total nitrogen and carbon - using elemental CNS analyzer, while calcium and magnesium were determined by AAS. The data on yield of both aerial parts and root dry biomass of radicchio showed that its treatment with Q4 and Q10 strains, as well as with their mixture, caused noticeably increase in this parameter in relation to the control, whereby the strain Q4 was more effective for aerial parts, while mix Q4+Q10 - for roots. The obtained data on the studied chemical parameters of radicchio root and aerial parts were in total accordance with their yield. Concluding, studied strains have a potential in promoting the biomass yield and main chemical growth parameters of both aerial parts and root of radicchio.

  17. SOME THEORETICAL MODELS EXPLAINING ADVERTISING EFFECTS

    Directory of Open Access Journals (Sweden)

    Vasilica Magdalena SOMEŞFĂLEAN

    2014-06-01

    Full Text Available Persuade clients is still the main focus of the companies, using a set of methods and techniques designed to influence their behavior, in order to obtain better results (profits over a longer period of time. Since the late nineteenth - early twentieth century, the american E.St.Elmo Lewis, considered a pioneer in advertising and sales, developed the first theory, AIDA model, later used by marketers and advertisers to develop a marketing communications strategy. Later studies have developed other models that are the main subject of this research, which explains how and why persuasive communication works, to understand why some approaches are effective and others are not.

  18. Model Verification and Validation Concepts for a Probabilistic Fracture Assessment Model to Predict Cracking of Knife Edge Seals in the Space Shuttle Main Engine High Pressure Oxidizer

    Science.gov (United States)

    Pai, Shantaram S.; Riha, David S.

    2013-01-01

    Physics-based models are routinely used to predict the performance of engineered systems to make decisions such as when to retire system components, how to extend the life of an aging system, or if a new design will be safe or available. Model verification and validation (V&V) is a process to establish credibility in model predictions. Ideally, carefully controlled validation experiments will be designed and performed to validate models or submodels. In reality, time and cost constraints limit experiments and even model development. This paper describes elements of model V&V during the development and application of a probabilistic fracture assessment model to predict cracking in space shuttle main engine high-pressure oxidizer turbopump knife-edge seals. The objective of this effort was to assess the probability of initiating and growing a crack to a specified failure length in specific flight units for different usage and inspection scenarios. The probabilistic fracture assessment model developed in this investigation combined a series of submodels describing the usage, temperature history, flutter tendencies, tooth stresses and numbers of cycles, fatigue cracking, nondestructive inspection, and finally the probability of failure. The analysis accounted for unit-to-unit variations in temperature, flutter limit state, flutter stress magnitude, and fatigue life properties. The investigation focused on the calculation of relative risk rather than absolute risk between the usage scenarios. Verification predictions were first performed for three units with known usage and cracking histories to establish credibility in the model predictions. Then, numerous predictions were performed for an assortment of operating units that had flown recently or that were projected for future flights. Calculations were performed using two NASA-developed software tools: NESSUS(Registered Trademark) for the probabilistic analysis, and NASGRO(Registered Trademark) for the fracture

  19. Effects of light quality on main health-promoting compounds and antioxidant capacity of Chinese kale sprouts.

    Science.gov (United States)

    Qian, Hongmei; Liu, Tianyu; Deng, Mingdan; Miao, Huiying; Cai, Congxi; Shen, Wangshu; Wang, Qiaomei

    2016-04-01

    The effects of different light qualities, including white, red and blue lights, on main health-promoting compounds and antioxidant capacity of Chinese kale sprouts were investigated using light-emitting diodes (LEDs) as a light source. Our results showed that blue light treatment significantly decreased the content of gluconapin, the primary compound for bitter flavor in shoots, while increased the glucoraphanin content in roots. Moreover, the maximum content of vitamin C was detected in the white-light grown sprouts and the highest levels of total phenolic and anthocyanins, as well as the strongest antioxidant capacity were observed in blue-light grown sprouts. Taken together, the application of a colorful light source is a good practice for improvement of the consumers' acceptance and the nutritional phtyochemicals of Chinese kale sprouts. Copyright © 2015 Elsevier Ltd. All rights reserved.

  20. Effect of main inclusions on crack initiation in bearing steel in the very high cycle fatigue regime

    Science.gov (United States)

    Gu, Chao; Bao, Yan-ping; Gan, Peng; Wang, Min; He, Jin-shan

    2018-06-01

    This work aims to investigate the effect of main inclusions on crack initiation in bearing steel in the very high cycle fatigue (VHCF) regime. The size and type of inclusions in the steel were quantitatively analyzed, and VHCF tests were performed. Some fatigue cracks were found to be initiated in the gaps between inclusions (Al2O3, MgO-Al2O3) and the matrix, while other cracks originated from the interior of inclusions (TiN, MnS). To explain the related mechanism, the tessellated stresses between inclusions and the matrix were calculated and compared with the yield stress of the matrix. Results revealed that the inclusions could be classified into two types under VHCF; of these two, only one type could be regarded as holes. Findings in this research provide a better understanding of how inclusions affect the high cycle fatigue properties of bearing steel.

  1. Studying the effect of a variation in the main parameters on stability of homogeneous earth dams using design experiment

    Directory of Open Access Journals (Sweden)

    Lakehal Rida

    2017-09-01

    Full Text Available Deterministic approaches such as the limit equilibrium method (LEM especially Bishop modified method has been traditionally used to evaluate the stability of embankment dams. However, the uncertainty associated with the material properties necessitates the use of the probabilistic method to account the sensitivity of this uncertainty on the response of the deterministic approaches. In this study, the authors propose the application of design experiment, especially central composite design (CCD to determine the effects of independent uncertain parameters on the response of stability. A second-order polynomial model with cross terms is used to create an approximating function referred to as response surface for the implicit limit state surface, for which the input data were provided by stability analyses of different heights of homogeneous earth dams (10 m, 20 m, and 30 m with a depth ratio of DH = 1.5 and a circular slip surface using the Bishop modified limit equilibrium method. The proposed models obtained from this application represent higher prediction accuracy. The study of the effect of geotechnical parameters (material properties of embankment on safety factor show the importance of individual factors in level of linear effect with a positive effect of c’ or φ’ and a negative effect of H, γd, γsat and significant influence of two-factors interaction, the effect of c’ highly dependent on H, β, γd and φ’. Moreover, the effect of φ’ is dependent on the values of H and β. Lastly, the optimization of safety factor with respect to the range of values of material properties was made, and two failures modes are discussed which are (φ’, c’ reduction and γd increase.

  2. RIMAPS characterization of a surface in the variable aperture fracture model and determination of the main paths for water flow

    International Nuclear Information System (INIS)

    Fuentes, Nestor O.

    2003-01-01

    To understand the real incidence of fracture geometry in the unsteady behavior of flowing water channels, the RIMAPS (Rotated Image with Maximum Average Power Spectrum) technique is used to determine the main directions of these channels. This new characterization technique works on digitized images obtained from the surfaces under study. The present work presents the results of a comparison between the flow directions predicted by RIMAPS and the real channels directions observed in a laboratory experiment. A perfect accordance was verified between the directions obtained in both cases. It can be concluded from these results that geometrical characteristics of a fracture surface determine the main path directions for water flow. (author)

  3. RESEARCH OF THE HIGH HARMONICS INDIVIDUAL BLADE CONTROL EFFECT ON VIBRATIONS CAUSED BY THE HELICOPTER MAIN ROTOR THRUST

    OpenAIRE

    2016-01-01

    The paper presents numerical results analysis of main rotor vibration due to helicopter main rotor thrust pulsation.The calculation method, the object of research and numerical research results with the aim to reduce the amplitude of the vibrations transmitted to the hub from the helicopters main rotor by the individual blade control in azimuth by the installation angle of blades cyclic changes are set out in the article. The individual blades control law for a five-blade main rotor based on ...

  4. Cold flow testing of the Space Shuttle Main Engine alternate turbopump development high pressure fuel turbine model

    Science.gov (United States)

    Gaddis, Stephen W.; Hudson, Susan T.; Johnson, P. D.

    1992-01-01

    NASA's Marshall Space Flight Center has established a cold airflow turbine test program to experimentally determine the performance of liquid rocket engine turbopump drive turbines. Testing of the SSME alternate turbopump development (ATD) fuel turbine was conducted for back-to-back comparisons with the baseline SSME fuel turbine results obtained in the first quarter of 1991. Turbine performance, Reynolds number effects, and turbine diagnostics, such as stage reactions and exit swirl angles, were investigated at the turbine design point and at off-design conditions. The test data showed that the ATD fuel turbine test article was approximately 1.4 percent higher in efficiency and flowed 5.3 percent more than the baseline fuel turbine test article. This paper describes the method and results used to validate the ATD fuel turbine aerodynamic design. The results are being used to determine the ATD high pressure fuel turbopump (HPFTP) turbine performance over its operating range, anchor the SSME ATD steady-state performance model, and validate various prediction and design analyses.

  5. Blooms of the Toxic Dinoflagellate Alexandrium fundyense in the Gulf of Maine: Investigations Using a Physical-Biological Model

    National Research Council Canada - National Science Library

    Stock, Charles

    2005-01-01

    .... In this thesis, a biological model of the A. fundyense life cycle developed from laboratory and field data is combined with a circulation model to test hypothesis concerning the factors governing...

  6. An international review of the main cost-effectiveness drivers of virtual colonography versus conventional colonoscopy for colorectal cancer screening: is the tide changing due to adherence?

    Science.gov (United States)

    Kriza, Christine; Emmert, Martin; Wahlster, Philip; Niederländer, Charlotte; Kolominsky-Rabas, Peter

    2013-11-01

    The majority of recent cost-effectiveness reviews concluded that computerised tomographic colonography (CTC) is not a cost-effective colorectal cancer (CRC) screening strategy yet. The objective of this review is to examine cost-effectiveness of CTC versus optical colonoscopy (COL) for CRC screening and identify the main drivers influencing cost-effectiveness due to the emergence of new research. A systematic review was conducted for cost-effectiveness studies comparing CTC and COL as a screening tool and providing outcomes in life-years saved, published between January 2006 and November 2012. Nine studies were included in the review. There was considerable heterogeneity in modelling complexity and methodology. Different model assumptions and inputs had large effects on resulting cost-effectiveness of CTC and COL. CTC was found to be dominant or cost-effective in three studies, assuming the most favourable scenario. COL was found to be not cost effective in one study. CTC has the potential to be a cost-effective CRC screening strategy when compared to COL. The most important assumptions that influenced the cost-effectiveness of CTC and COL were related to CTC threshold-based reporting of polyps, CTC cost, CTC sensitivity for large polyps, natural history of adenoma transition to cancer, AAA parameters and importantly, adherence. There is a strong need for a differential consideration of patient adherence and compliance to CTC and COL. Recent research shows that laxative-free CTC screening has the potential to become a good alternative screening method for CRC as it can improve patient uptake of screening. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

  7. An international review of the main cost-effectiveness drivers of virtual colonography versus conventional colonoscopy for colorectal cancer screening: Is the tide changing due to adherence?

    Energy Technology Data Exchange (ETDEWEB)

    Kriza, Christine, E-mail: Christine.kriza@uk-erlangen.de [Interdisciplinary Centre for Health Technology Assessment and Public Health, University of Erlangen-Nuremberg, National BMBF-Cluster of Excellence, “Medical Technologies - Medical Valley EMN”, Schwabachanlage 6, 91054 Erlangen (Germany); Emmert, Martin, E-mail: Martin.Emmert@fau.de [School of Business and Economics, Institute of Management, University of Erlangen-Nuremberg, Lange Gasse 20, 90403 Nuremberg (Germany); Wahlster, Philip, E-mail: Philip.wahlster@uk-erlangen.de [Interdisciplinary Centre for Health Technology Assessment and Public Health, University of Erlangen-Nuremberg, National BMBF-Cluster of Excellence, “Medical Technologies - Medical Valley EMN”, Schwabachanlage 6, 91054 Erlangen (Germany); Niederländer, Charlotte, E-mail: Charlotte.niederlaender@uk-erlangen.de [Interdisciplinary Centre for Health Technology Assessment and Public Health, University of Erlangen-Nuremberg, National BMBF-Cluster of Excellence, “Medical Technologies - Medical Valley EMN”, Schwabachanlage 6, 91054 Erlangen (Germany); Kolominsky-Rabas, Peter, E-mail: Peter.kolominsky@uk-erlangen.de [Interdisciplinary Centre for Health Technology Assessment and Public Health, University of Erlangen-Nuremberg, National BMBF-Cluster of Excellence, “Medical Technologies - Medical Valley EMN”, Schwabachanlage 6, 91054 Erlangen (Germany)

    2013-11-01

    Objectives: The majority of recent cost-effectiveness reviews concluded that computerised tomographic colonography (CTC) is not a cost-effective colorectal cancer (CRC) screening strategy yet. The objective of this review is to examine cost-effectiveness of CTC versus optical colonoscopy (COL) for CRC screening and identify the main drivers influencing cost-effectiveness due to the emergence of new research. Methods: A systematic review was conducted for cost-effectiveness studies comparing CTC and COL as a screening tool and providing outcomes in life-years saved, published between January 2006 and November 2012. Results: Nine studies were included in the review. There was considerable heterogeneity in modelling complexity and methodology. Different model assumptions and inputs had large effects on resulting cost-effectiveness of CTC and COL. CTC was found to be dominant or cost-effective in three studies, assuming the most favourable scenario. COL was found to be not cost effective in one study. Conclusions: CTC has the potential to be a cost-effective CRC screening strategy when compared to COL. The most important assumptions that influenced the cost-effectiveness of CTC and COL were related to CTC threshold-based reporting of polyps, CTC cost, CTC sensitivity for large polyps, natural history of adenoma transition to cancer, AAA parameters and importantly, adherence. There is a strong need for a differential consideration of patient adherence and compliance to CTC and COL. Recent research shows that laxative-free CTC screening has the potential to become a good alternative screening method for CRC as it can improve patient uptake of screening.

  8. An international review of the main cost-effectiveness drivers of virtual colonography versus conventional colonoscopy for colorectal cancer screening: Is the tide changing due to adherence?

    International Nuclear Information System (INIS)

    Kriza, Christine; Emmert, Martin; Wahlster, Philip; Niederländer, Charlotte; Kolominsky-Rabas, Peter

    2013-01-01

    Objectives: The majority of recent cost-effectiveness reviews concluded that computerised tomographic colonography (CTC) is not a cost-effective colorectal cancer (CRC) screening strategy yet. The objective of this review is to examine cost-effectiveness of CTC versus optical colonoscopy (COL) for CRC screening and identify the main drivers influencing cost-effectiveness due to the emergence of new research. Methods: A systematic review was conducted for cost-effectiveness studies comparing CTC and COL as a screening tool and providing outcomes in life-years saved, published between January 2006 and November 2012. Results: Nine studies were included in the review. There was considerable heterogeneity in modelling complexity and methodology. Different model assumptions and inputs had large effects on resulting cost-effectiveness of CTC and COL. CTC was found to be dominant or cost-effective in three studies, assuming the most favourable scenario. COL was found to be not cost effective in one study. Conclusions: CTC has the potential to be a cost-effective CRC screening strategy when compared to COL. The most important assumptions that influenced the cost-effectiveness of CTC and COL were related to CTC threshold-based reporting of polyps, CTC cost, CTC sensitivity for large polyps, natural history of adenoma transition to cancer, AAA parameters and importantly, adherence. There is a strong need for a differential consideration of patient adherence and compliance to CTC and COL. Recent research shows that laxative-free CTC screening has the potential to become a good alternative screening method for CRC as it can improve patient uptake of screening

  9. Protective effect of thymoquinone, the main component of Nigella Sativa, against diazinon cardio-toxicity in rats.

    Science.gov (United States)

    Danaei, Gholam Hassan; Memar, Bahram; Ataee, Ramin; Karami, Mohammad

    2018-04-12

    Several studies have shown that oxidative stress and cell damage can occur at very early stages of diazinon (DZN) exposure. The present study was designed to determine the beneficial effect of thymoquinone (Thy), the main component of Nigella sativa (black seed or black cumin), against DZN cardio-toxicity in rats. In the present experimental study, 48 male Wistar rats were randomly divided into six groups: control (corn oil gavages), DZN gavages (20 mg/kg/day), Thy gavages (10 mg/kg/day) and Thy + DVN gavages (2.5, 5 and 10 mg/kg/day). Treatments were continued for 28 days, then the animals were anesthetized by ether and superoxide dismutase (SOD), catalase (CAT), glutathione S-transferase (GST), lactate dehydrogenize (LDH) and glutathione peroxide (GPX) activity was evaluated. In addition, glutathione (GSH) and malondialdehyde (MDA) the heart tissue and creatinephosphokinase-MB (CPK-MB) and troponin (TPI) levels and cholinesterase activity in the blood were evaluated. DZN-induced oxidative damage and elevated the levels of the cardiac markers CK-MB, TPI, MDA and LDH and decreased SOD, CAT and cholinesterase activity and GSH level compared with the control group. Treatment with Thy reduced DZN cardio-toxicity and cholinesterase activity. The success of Thy supplementation against DZN toxicity can be attributed to the antioxidant effects of its constituents. Administration of Thy as a natural antioxidant decreased DZN cardio-toxicity and improved cholinesterase activity in rats through the mechanism of free radical scavenging.

  10. Cost-effectiveness analysis of main diagnosis tools in women with overactive bladder. Clinical history, micturition diary and urodynamic study.

    Science.gov (United States)

    López-Fando, L; Carracedo, D; Jiménez, M; Gómez de Vicente, J M; Martínez, L; Gómez-Cañizo, C; Gómez, V; Burgos, F J

    2015-01-01

    The aim of the present clinical research is to analyze, in the light of the best scientific evidence, the performance and the cost of the main diagnostic tools for overactive bladder (OAB). It is an exploratory transversal study in which 199 women diagnosed of OAB between 2006 and 2008 were selected and underwent to following prospective analyses: physical examination, urine analysis, micturition diary (MD) and urodynamic study (UDS). A percentage of 80% was assumed as highly sensitive and a diagnostic difference among tests of 10% would be considered clinically relevant. Tests' sensitivity for diagnosis of OAB was statistically established by two ways: isolated and combined. Besides, the direct and indirect costs of these tests performance were conducted. Cost-effectiveness study of clinical history (CH), MD and US for the diagnosis of OAB was performed. Overall sensitivity for OAB diagnosis is low for the 3 tests used in isolated way, whilst the combination of any two tests shows good overall sensitivity. The combination of CH and MD has appeared as the most cost-effective alternative to OAB diagnosis. For OAB diagnosis, CH-DM combination shows the same sensitivity than the association of either of them with the UDS, but unlike to these, it shows the lowest cost. Copyright © 2013 AEU. Publicado por Elsevier España, S.L.U. All rights reserved.

  11. Perceptions of healthcare professionals regarding the main challenges and barriers to effective hospital infection control in Mongolia: a qualitative study

    Directory of Open Access Journals (Sweden)

    Ider Bat-Erdene

    2012-07-01

    Full Text Available Abstract Background It is not fully understood why healthcare decision-makers of developing countries often give low priority to infection control and why they are unable to implement international guidelines. This study aimed to identify the main perceived challenges and barriers that hinder the effective implementation of infection control programmes in Mongolia. Methods In 2008, qualitative research involving 4 group and 55 individual interviews was conducted in the capital city of Mongolia and two provincial centres. Results A total of 87 health professionals participated in the study, including policy and hospital-level managers, doctors, nurses and infection control practitioners. Thematic analysis revealed a large number of perceived challenges and barriers to the formulation and implementation of infection control policy. These challenges and barriers were complex in nature and related to poor funding, suboptimal knowledge and attitudes, and inadequate management. The study results suggest that the availability of infection control policy and guidelines, and the provision of specific recommendations for low-resource settings, do not assure effective implementation of infection control programmes. Conclusions The current infection control system in Mongolia is likely to remain ineffective unless the underlying barriers and challenges are adequately addressed. Multifaceted interventions with logistical, educational and management components that are specific to local circumstances need to be designed and implemented in Mongolia. The importance of international peer support is highlighted.

  12. The roles of resilience and childhood trauma history: main and moderating effects on postpartum maternal mental health and functioning.

    Science.gov (United States)

    Sexton, Minden B; Hamilton, Lindsay; McGinnis, Ellen W; Rosenblum, Katherine L; Muzik, Maria

    2015-03-15

    Recently postpartum women participated to investigate main and moderating influences of resilience and childhood history of maltreatment on posttraumatic stress disorder (PTSD), major depressive disorder (MDD), parental sense of mastery, and family functioning. At 4-months postpartum, 214 mothers (145 with a history of childhood abuse or neglect) completed interviews assessing mental health symptoms, positive functioning, resilience and trauma history. Multiple and moderated linear regression with the Connor-Davidson Resilience Scale (CD-RISC) and Childhood Trauma Questionnaires (CTQ) were conducted to assess for main and moderating effects. Resilience, childhood trauma severity, and their interaction predicted postpartum PTSD and MDD. In mothers without childhood maltreatment, PTSD was absent irrespective of CD-RISC scores. However, for those with the highest quartile of CTQ severity, 8% of those with highest resilience in contrast with 58% of those with lowest CD-RISC scores met PTSD diagnostic criteria. Similar, in those with highest resilience, no mothers met criteria for postpartum MDD, irrespective of childhood trauma, while for those with lowest quartile of resilience, 25% with lowest CTQ severity and 68% of those with highest CTQ severity were depressed. The CD-RISC, but not the CTQ, was predictive of postpartum sense of competence. The CD-RISC and the CTQ were predictive of postpartum family functioning, though no moderating influence of resilience on childhood trauma was found. Resilience is associated with reduced psychopathology and improved wellbeing in all mothers. It further serves as a buffer against psychiatric symptoms following childhood trauma. Such findings may assist in identification of those at greatest risk of adverse functioning postpartum, utilization of resilience-enhancing intervention may benefit perinatal wellness, and reduce intergenerational transmission of risk. Copyright © 2015 Elsevier B.V. All rights reserved.

  13. In Vitro Inhibitory Effect of Berberis vulgaris (Berberidaceae) and Its Main Component, Berberine against Different Leishmania Species.

    Science.gov (United States)

    Mahmoudvand, Hossein; Sharififar, Fariba; Sharifi, Iraj; Ezatpour, Behrouz; Fasihi Harandi, Majid; Makki, Mahsa Sadat; Zia-Ali, Naser; Jahanbakhsh, Sareh

    2014-03-01

    Leishmaniasis has been identified as a major public health problem in tropical and sub-tropical countries. The present study was aimed to investigate antileishmanial effects of various extracts of Berberis vulgaris also its active compoenent, berberine against Leishmania tropica and L. infantum species on in vitro experiments. In this study in vitro antileishmanial activity of various extracts of B. vulgaris also its active compoenent, berberine against promastigote and amastigote stages of L. tropica and L. infantum was evaluated, using MTT assay and in a macrophage model, respectively. Furthermore, infectivity rate and cytotoxicity effects of B. vulgaris and berberine in murine macrophage cells were investigated. The findings of optical density (OD) and IC50 indicated that B. vulgaris particulary berberine significantly (P<0.05) inhibited the growth rate of promastigote stage of L.tropica and L.infantum in comparison to meglumine antimoniate (MA). In addition, B. vulgaris and berberine significantly (P<0.05) decreased the mean number of amastigotes in each macrophage as compared with positive control. In the evaluation of cytotoxicity effects, it could be observed that berberine as compared with B. vulgaris exhibited more cytotoxicity against murine macrophages. Results also showed that when parasites were pre-incubated with B. vulgaris their ability to infect murine macrophages was significantly decreased. B.vulgaris particularly berberine exhibited potent in vitro leishmanicidal effects against L. tropica and L.infantum. Further works are required to evaluate the antileishmanial effects of B.vulgaris on Leishmania species using clinical settings.

  14. Development and evaluation of a meteorological model system for assessing the effect of environmental measures on climate and air quality. Vol. 1: Main part and appendices 1 through 5. Final report; Entwicklung und Evaluierung eines meteorologischen Modellsystems zur Folgenabschaetzung von Umwelteingriffen auf Klima und Luftqualitaet. Bd. 1: Hauptteil und Anhaenge 1 bis 5. Abschlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    Bigalke, K. [METCON Umweltmeteorologische Beratung, Pinneberg (Germany); Schluenzen, K.H. [Hamburg Univ. (Germany). Meteorologisches Inst.

    2001-09-01

    The project focused on the development of a low-cost planning tool for authorities and consulting engineers which meets the envisaged national quality standards (VDI standards). The program system METRAS{sup +} consists of four components for preparation, implementation and quality assurance of mesoscale model calculations, all under Windows. The program system will not be commercialized; instead, it will be made available to interested users at a small fee by the Meteorological Institute of Hamburg University. [German] Ziel war die Bereitstellung eines kostenguenstigen Planungsinstrumentes fuer Behoerden und Beratungsunternehmen, das geplante nationale Qualitaetsnormen (VDI-Richtlinie) erfuellt. Vergleichbare Modelle existieren bislang nur im wissenschaftlichen Bereich, sind kaum qualitaetsgesichert und werden u.a. aus wirtschaftlichen Erwaegungen nur in Ausnahmefaellen eingesetzt. Das Programmsystem METRAS{sup +} setzt sich aus vier Programmkomponenten zusammen, die der Vorbereitung, Durchfuehrung und Qualitaetssicherung mesoskaliger Modellrechnungen dienen. Alle Programmkomponenten laufen unter einer gemeinsamen, anwenderfreundlichen Windowsoberflaeche. Um die breite Anwendung qualifizierter Untersuchungsmethoden im Umweltconsulting zu foerdern, ist geplant, METRAS{sup +} nicht kommerziell zu vertreiben und das Programmsystem interessierten Anwendern gegen einen geringen Kostenbeitrag zur Verfuegung zu stellen. Vertrieb und Oeffentlichkeitsarbeit sollen vom Meteorologischen Institut der Universitaet Hamburg geleistet werden. (orig.)

  15. Biophysical models of radiobiological effects

    International Nuclear Information System (INIS)

    Obaturov, G.M.

    1984-01-01

    Models of radiation effect on biological structures and objects are presented. Physical and molecular models based on target theory and DNA or chromosome injuries, respectively, and reparation ''saturation'' theory, are considered

  16. The effects of virtual reality displays on visual attention and detection of signals performance for main control room training

    International Nuclear Information System (INIS)

    Lin Shiaufeng; Lin Chiuhsiang Joe; Wang Rouwen; Yang Lichen; Yang Chihwei; Cheng Tsungchieh; Wang Jyhgang

    2011-01-01

    The nuclear power plant (NPP) mainly serve the purpose to provide low-cost and stable electricity for the people, but this purpose must be dependent upon the premise of 'safety first.' The reason for this is that the occurrence of nuclear power plant accidents could cause catastrophic damage to the people, property, society, and the environment. Therefore, training in superior and high reliability system is very important in accident prevention. In recent years, the Virtual Reality (VR) technology advances very fast as well as the technology for e-learning environment. VR systems have been applied for education, safety training of NPP and flying simulators. In particular, VR is an interactive and reactive technology; it allows users to interact and navigate with objects in the virtual environment. Development of VR and simulation techniques contributes to an accurate and immersive training environment for NPP operators. Main Control Room (MCR) training simulator based on VR is a more cost effective and efficient alternative to traditional simulator based training methods. The VR simulation for MCR training is a complex task. Since VR not only reinforces the visual presentation of the training materials but also provides ways to interact with the training system, it becomes more flexible and possibly more powerful in the training system. In the VR training system, the MCR operators may use just one display to view the wide range of the real world displays. The field of view (FOV) will be different from the real MCR environment in which many displays exist for the operators to view. Thus operator's immersion and visual attention will be reduced. This is the problem of MCR virtual training compared with the traditional simulator based training systems. Therefore, improving the operator's visual attention and the detection of signals in VR training system is a very important issue. This investigation intends to contribute in assessing benefits of visual attention and

  17. Revised nonstochastic health effects models

    International Nuclear Information System (INIS)

    Yaniv, S.S.; Scott, B.R.

    1991-01-01

    In 1989, the U.S. Nuclear Regulatory Commission (NRC) published a revision of the 1985 report, Health Effects Models for Nuclear Power Plant Accident Consequence Analysis, NUREG/CR-4214, that included models for early occurring and continuing nonstochastic effects, cancers and thyroid nodules, and genetic effects. This paper discusses specific models for lethality from early occurring and continuing effects. For brevity, hematopoietic-syndrome lethality is called hematopoietic death; pulmonary-syndrome lethality is called pulmonary death; and gastrointestinal syndrome lethality is called gastrointestinal death. Two-parameter Weibull risk functions are recommended for estimating the risk of hematopoietic, pulmonary, or gastrointestinal death. The risks are obtained indirectly by using hazard functions; as a result, this type of approach has been called hazard-function modeling and the models generated are called hazard-function models. In the 1989 NUREG/CR-4214 report, changes were made in the parameter values for a number of effects, and the models used to estimate hematopoietic and pulmonary deaths were substantially revised. Upper and lower estimates of model parameters are provided for all early health effects models. In this paper, we discuss the 1989 models for hematopoietic and pulmonary deaths, highlighting the differences between the 1989 and 1985 models. In addition, we give the reasons for which the 1985 models were modified

  18. Secondary radiation damage as the main cause for unexpected volume effects: A histopathologic study of the parotid gland

    International Nuclear Information System (INIS)

    Konings, Antonius W.T.; Faber, Hette; Cotteleer, Femmy; Vissink, Arjan; Coppes, Rob P.

    2006-01-01

    Purpose: To elucidate with a histopathological study the mechanism of region-dependent volume effects in the partly irradiated parotid gland of the rat. Methods and Materials: Wistar rats were locally X-irradiated with collimators with conformal radiation portals for 100% volume and 50% cranial/caudal partial volumes. Single doses up to 40 Gy were applied. Parotid saliva samples were collected, and the three lobes of the parotid gland were examined individually on the macro- and micromorphologic level up to 1 year after irradiation. Results: Dose-dependent loss of gland weight was observed 1 year after total or partial X-irradiation. Weight loss of the glands correlated very well with loss of secretory function. Irradiating the cranial 50% volume (implicating a shielded lateral lobe) resulted in substantially more damage in terms of weight loss and loss of secretory function than 50% caudal irradiation (shielding the ventral and dorsal lobe). Histologic examinations of the glands 1 year after irradiation revealed that the shielded lateral lobe was severely affected, in contrast to the shielded ventral and dorsal lobes. Time studies showed that irradiation of the cranial 50% volume caused late development of secondary damage in the shielded lateral lobe, becoming manifest between 240 and 360 days after irradiation. The possible clinical significance of this finding is discussed. Conclusion: It is concluded that the observed region-dependent volume effect for late function loss in the rat parotid gland after partial irradiation is mainly caused by secondary events in the shielded lateral lobe. The most probable first step (primary radiation event) in the development of this secondary damage is radiation exposure to the hilus region (located between the ventral and dorsal lobe). By injuring major excretory ducts and supply routes for blood and nerves in this area, the facility system necessary for proper functioning of the nonexposed lateral lobe is seriously affected

  19. Safeguards system effectiveness modeling

    International Nuclear Information System (INIS)

    Bennett, H.A.; Boozer, D.D.; Chapman, L.D.; Daniel, S.L.; Engi, D.; Hulme, B.L.; Varnado, G.B.

    1976-01-01

    A general methodology for the comparative evaluation of physical protection system effectiveness at nuclear facilities is presently under development. The approach is applicable to problems of sabotage or theft at fuel cycle facilities. The overall methodology and the primary analytic techniques used to assess system effectiveness are briefly outlined

  20. Safeguards system effectiveness modeling

    International Nuclear Information System (INIS)

    Boozer, D.D.; Hulme, B.L.; Daniel, S.L.; Varnado, G.B.; Bennett, H.A.; Chapman, L.D.; Engi, D.

    1976-09-01

    A general methodology for the comparative evaluation of physical protection system effectiveness at nuclear facilities is presently under development. The approach is applicable to problems of sabotage or theft at fuel cycle facilities. In this paper, the overall methodology and the primary analytic techniques used to assess system effectiveness are briefly outlined

  1. Safeguards system effectiveness modeling

    International Nuclear Information System (INIS)

    Bennett, H.A.; Boozer, D.D.; Chapman, L.D.; Daniel, S.L.; Engi, D.; Hulme, B.L.; Varnado, G.B.

    1976-01-01

    A general methodology for the comparative evaluation of physical protection system effectiveness at nuclear facilities is presently under development. The approach is applicable to problems of sabotage or theft at fuel cycle facilities. In this paper, the overall methodology and the primary analytic techniques used to assess system effectiveness are briefly outlined

  2. A multiclass vehicular dynamic traffic flow model for main roads and dedicated lanes/roads of multimodal transport network

    Energy Technology Data Exchange (ETDEWEB)

    Sossoe, K.S., E-mail: kwami.sossoe@irt-systemx.fr [TECHNOLOGICAL RESEARCH INSTITUTE SYSTEMX (France); Lebacque, J-P., E-mail: jean-patrick.lebacque@ifsttar.fr [UPE/IFSTTAR-COSYS-GRETTIA (France)

    2015-03-10

    We present in this paper a model of vehicular traffic flow for a multimodal transportation road network. We introduce the notion of class of vehicles to refer to vehicles of different transport modes. Our model describes the traffic on highways (which may contain several lanes) and network transit for pubic transportation. The model is drafted with Eulerian and Lagrangian coordinates and uses a Logit model to describe the traffic assignment of our multiclass vehicular flow description on shared roads. The paper also discusses traffic streams on dedicated lanes for specific class of vehicles with event-based traffic laws. An Euler-Lagrangian-remap scheme is introduced to numerically approximate the model’s flow equations.

  3. How to Sell SaaS: A Model for Main Factors of Marketing and Selling Software-as-a-Service

    OpenAIRE

    Tyrväinen, Pasi; Selin, Joona

    2011-01-01

    Software-as-a-Service providers have been growing fast while the contemporary research literature has neglected analysis of their business-critical marketing and sales processes. In this paper we collect the key factors characterizing how to market and sell SaaS to business customers into an eight dimensional model. We also use an explorative multi-case study to observe six SaaS providers and validate the model. The interviewed providers emphasized use of the Internet for ma...

  4. Anticancer Effect of Ginger Extract against Pancreatic Cancer Cells Mainly through Reactive Oxygen Species-Mediated Autotic Cell Death

    Science.gov (United States)

    Akimoto, Miho; Iizuka, Mari; Kanematsu, Rie; Yoshida, Masato; Takenaga, Keizo

    2015-01-01

    The extract of ginger (Zingiber officinale Roscoe) and its major pungent components, [6]-shogaol and [6]-gingerol, have been shown to have an anti-proliferative effect on several tumor cell lines. However, the anticancer activity of the ginger extract in pancreatic cancer is poorly understood. Here, we demonstrate that the ethanol-extracted materials of ginger suppressed cell cycle progression and consequently induced the death of human pancreatic cancer cell lines, including Panc-1 cells. The underlying mechanism entailed autosis, a recently characterized form of cell death, but not apoptosis or necroptosis. The extract markedly increased the LC3-II/LC3-I ratio, decreased SQSTM1/p62 protein, and enhanced vacuolization of the cytoplasm in Panc-1 cells. It activated AMPK, a positive regulator of autophagy, and inhibited mTOR, a negative autophagic regulator. The autophagy inhibitors 3-methyladenine and chloroquine partially prevented cell death. Morphologically, however, focal membrane rupture, nuclear shrinkage, focal swelling of the perinuclear space and electron dense mitochondria, which are unique morphological features of autosis, were observed. The extract enhanced reactive oxygen species (ROS) generation, and the antioxidant N-acetylcystein attenuated cell death. Our study revealed that daily intraperitoneal administration of the extract significantly prolonged survival (P = 0.0069) in a peritoneal dissemination model and suppressed tumor growth in an orthotopic model of pancreatic cancer (P < 0.01) without serious adverse effects. Although [6]-shogaol but not [6]-gingerol showed similar effects, chromatographic analyses suggested the presence of other constituent(s) as active substances. Together, these results show that ginger extract has potent anticancer activity against pancreatic cancer cells by inducing ROS-mediated autosis and warrants further investigation in order to develop an efficacious candidate drug. PMID:25961833

  5. Anticancer Effect of Ginger Extract against Pancreatic Cancer Cells Mainly through Reactive Oxygen Species-Mediated Autotic Cell Death.

    Directory of Open Access Journals (Sweden)

    Miho Akimoto

    Full Text Available The extract of ginger (Zingiber officinale Roscoe and its major pungent components, [6]-shogaol and [6]-gingerol, have been shown to have an anti-proliferative effect on several tumor cell lines. However, the anticancer activity of the ginger extract in pancreatic cancer is poorly understood. Here, we demonstrate that the ethanol-extracted materials of ginger suppressed cell cycle progression and consequently induced the death of human pancreatic cancer cell lines, including Panc-1 cells. The underlying mechanism entailed autosis, a recently characterized form of cell death, but not apoptosis or necroptosis. The extract markedly increased the LC3-II/LC3-I ratio, decreased SQSTM1/p62 protein, and enhanced vacuolization of the cytoplasm in Panc-1 cells. It activated AMPK, a positive regulator of autophagy, and inhibited mTOR, a negative autophagic regulator. The autophagy inhibitors 3-methyladenine and chloroquine partially prevented cell death. Morphologically, however, focal membrane rupture, nuclear shrinkage, focal swelling of the perinuclear space and electron dense mitochondria, which are unique morphological features of autosis, were observed. The extract enhanced reactive oxygen species (ROS generation, and the antioxidant N-acetylcystein attenuated cell death. Our study revealed that daily intraperitoneal administration of the extract significantly prolonged survival (P = 0.0069 in a peritoneal dissemination model and suppressed tumor growth in an orthotopic model of pancreatic cancer (P < 0.01 without serious adverse effects. Although [6]-shogaol but not [6]-gingerol showed similar effects, chromatographic analyses suggested the presence of other constituent(s as active substances. Together, these results show that ginger extract has potent anticancer activity against pancreatic cancer cells by inducing ROS-mediated autosis and warrants further investigation in order to develop an efficacious candidate drug.

  6. Bioavailable soil P as a main key for sustainable agriculture: its functional model determined using isotopic tracers

    Energy Technology Data Exchange (ETDEWEB)

    Fardeau, J.C.; Guiraud, G.; Marol, C.

    1994-12-31

    Sustainable agriculture is defined in many ways. In all of them, two main complementary concepts appear: this agriculture must firstly satisfy the human needs of foods for the present and secondly must not compromise the ability for the future generations to meet their needs. Therefore, concerning P, the sustainability in an ecosystem can be maintained if, and only if: (i) bioavailable soil P is not a limiting factor of crop yields in the considered conditions; (ii) all the parameters describing the available soil P will be unmodified each time that P is simultaneously taken by crops and returned to soils; (iii) P inputs and outputs must be without negative consequences on environment. Whatever the ecosystem, P nutrition can be described in terms of fluxes of P between soil and plant roots. The isotopic exchange method gives informations not only on bioavailable soil P but also on potential fluxes of P between soil and soil-solution. As roots take phosphorus in the soil solution it is concluded that this method can be used to predict not only potential P uptake by plants or crops in native soils but also the contribution to crop nutrition of a P application in soil. Isotopic tracers of P seem to be, at the present time, the simplest tool useful to describe, with a high accuracy, the main link of P cycle in sustainable agriculture: the bioavailable soil P. (authors). 9 refs., 1 fig., 1 tab. (authors).

  7. Bioavailable soil P as a main key for sustainable agriculture: its functional model determined using isotopic tracers

    International Nuclear Information System (INIS)

    Fardeau, J.C.; Guiraud, G.; Marol, C.

    1994-01-01

    Sustainable agriculture is defined in many ways. In all of them, two main complementary concepts appear: this agriculture must firstly satisfy the human needs of foods for the present and secondly must not compromise the ability for the future generations to meet their needs. Therefore, concerning P, the sustainability in an ecosystem can be maintained if, and only if: (i) bioavailable soil P is not a limiting factor of crop yields in the considered conditions; (ii) all the parameters describing the available soil P will be unmodified each time that P is simultaneously taken by crops and returned to soils; (iii) P inputs and outputs must be without negative consequences on environment. Whatever the ecosystem, P nutrition can be described in terms of fluxes of P between soil and plant roots. The isotopic exchange method gives informations not only on bioavailable soil P but also on potential fluxes of P between soil and soil-solution. As roots take phosphorus in the soil solution it is concluded that this method can be used to predict not only potential P uptake by plants or crops in native soils but also the contribution to crop nutrition of a P application in soil. Isotopic tracers of P seem to be, at the present time, the simplest tool useful to describe, with a high accuracy, the main link of P cycle in sustainable agriculture: the bioavailable soil P. (authors). 9 refs., 1 fig., 1 tab. (authors)

  8. In Vitro Inhibitory Effect of Berberis vulgaris (Berberidaceae and Its Main Component, Berberine against Different Leishmania Species.

    Directory of Open Access Journals (Sweden)

    Hossein Mahmoudvand

    2014-03-01

    Full Text Available Leishmaniasis has been identified as a major public health problem in tropical and sub-tropical countries. The present study was aimed to investigate antileishmanial effects of various extracts of Berberis vulgaris also its active compoenent, berberine against Leishmania tropica and L. infantum species on in vitro experiments.In this study in vitro antileishmanial activity of various extracts of B. vulgaris also its active compoenent, berberine against promastigote and amastigote stages of L. tropica and L. infantum was evaluated, using MTT assay and in a macrophage model, respectively. Furthermore, infectivity rate and cytotoxicity effects of B. vulgaris and berberine in murine macrophage cells were investigated.The findings of optical density (OD and IC50 indicated that B. vulgaris particulary berberine significantly (P<0.05 inhibited the growth rate of promastigote stage of L.tropica and L.infantum in comparison to meglumine antimoniate (MA. In addition, B. vulgaris and berberine significantly (P<0.05 decreased the mean number of amastigotes in each macrophage as compared with positive control. In the evaluation of cytotoxicity effects, it could be observed that berberine as compared with B. vulgaris exhibited more cytotoxicity against murine macrophages. Results also showed that when parasites were pre-incubated with B. vulgaris their ability to infect murine macrophages was significantly decreased.B.vulgaris particularly berberine exhibited potent in vitro leishmanicidal effects against L. tropica and L.infantum. Further works are required to evaluate the antileishmanial effects of B.vulgaris on Leishmania species using clinical settings.

  9. Urban Flooding Analysis Using Radar Rainfall Data and 2-D Hydrodynamic Model: A Pilot Study of Back Cover Area, Portland, Maine

    Energy Technology Data Exchange (ETDEWEB)

    Yan, Eugene [Argonne National Lab. (ANL), Argonne, IL (United States); Pierce, Julia [Argonne National Lab. (ANL), Argonne, IL (United States); Mahat, Vinod [Argonne National Lab. (ANL), Argonne, IL (United States); Jared, Alissa [Argonne National Lab. (ANL), Argonne, IL (United States); Collis, Scott [Argonne National Lab. (ANL), Argonne, IL (United States); Verner, Duane [Argonne National Lab. (ANL), Argonne, IL (United States); Wall, Thomas [Argonne National Lab. (ANL), Argonne, IL (United States)

    2016-11-01

    This project is a part of the Regional Resiliency Assessment Program, led by the Department of Homeland Security, to address flooding hazards of regional significance for Portland, Maine. The pilot study was performed by Argonne National Laboratory to identify differences in spatial rainfall distributions between the radar-derived and rain-gauge rainfall datasets and to evaluate their impacts on urban flooding. The flooding impact analysis utilized a high-resolution 2-dimensional (2-D) hydrodynamic model (15 ft by 15 ft) incorporating the buildings, streets, stream channels, hydraulic structures, an existing city storm drain system, and assuming a storm surge along the coast coincident with a heavy rainfall event. Two historical storm events from April 16, 2007, and September 29, 2015, were selected for evaluation. The radar-derived rainfall data at a 200-m resolution provide spatially-varied rainfall patterns with a wide range of intensities for each event. The resultant maximum flood depth using data from a single rain gauge within the study area could be off (either under- or over-estimated) by more than 10% in the 2007 storm and more than 60% in the 2015 storm compared to the radar-derived rainfall data. The model results also suggest that the inundation area with a flow depth at or greater than 0.5 ft could reach 11% (2007 storm) and 17% (2015 storm) of the total study area, respectively. The lowland areas within the neighborhoods of North Deering, East Deering, East and West Baysides and northeastern Parkside, appear to be more vulnerable to the flood hazard in both storm events. The high-resolution 2-D hydrodynamic model with high-resolution radar-derived rainfall data provides an excellent tool for detailed urban flood analysis and vulnerability assessment. The model developed in this study could be potentially used to evaluate any proposed mitigation measures and optimize their effects in the future for Portland, ME.

  10. Biophysical models of radiobiological effects

    International Nuclear Information System (INIS)

    Obaturov, G.M.

    1987-01-01

    Radiobiological effect models at different organization levels, developed by the author, are presented. Classification and analysis of concepts and biophysical models at molecular, genetic and cellular levels, developed by Soviet and foreign authors in comparison to inherent models, are conducted from the viewpoint of system approach to radiobiological processes and of modelling principles. Models are compared with each other, limits of their applicability and drawbacks are determined. Evaluation of the model truthfulness is conducted according to a number of criteria, ways of further investigations and experimental examination of some models are proposed

  11. Effects assessment of 10 functioning years on the main components of the molten salt PCS experimental facility of ENEA

    Science.gov (United States)

    Gaggioli, Walter; Di Ascenzi, Primo; Rinaldi, Luca; Tarquini, Pietro; Fabrizi, Fabrizio

    2016-05-01

    In the frame of the Solar Thermodynamic Laboratory, ENEA has improved CSP Parabolic Trough technologies by adopting new advanced solutions for linear tube receivers and by implementing a binary mixture of molten salt (60% NaNO3 and 40% KNO3) [1] as both heat transfer fluid and heat storage medium in solar field and in storage tanks, thus allowing the solar plants to operate at high temperatures up to 550°C. Further improvements have regarded parabolic mirror collectors, piping and process instrumentation. All the innovative components developed by ENEA, together with other standard parts of the plant, have been tested and qualified under actual solar operating conditions on the PCS experimental facility at the ENEA Casaccia Research Center in Rome (Italy). The PCS (Prova Collettori Solari, i.e. Test of Solar Collectors) facility is the main testing loop built by ENEA and it is unique in the world for what concerns the high operating temperature and the fluid used (mixture of molten salt). It consists in one line of parabolic trough collectors (test section of 100 m long life-size solar collectors) using, as heat transfer fluid, the aforesaid binary mixture of molten salt up to 10 bar, at high temperature in the range 270° and 550°C and a flow rate up to 6.5 kg/s. It has been working since early 2004 [2] till now; it consists in a unique closed loop, and it is totally instrumented. In this paper the effects of over ten years qualification tests on the pressurized tank will be presented, together with the characterization of the thermal losses of the piping of the molten salt circuit, and some observations performed on the PCS facility during its first ten years of operation.

  12. The Effects of Xiangqing Anodyne Spray on Treating Acute Soft-Tissue Injury Mainly Depend on Suppressing Activations of AKT and p38 Pathways

    Directory of Open Access Journals (Sweden)

    Shudong Wang

    2016-01-01

    Full Text Available Objectives. In the present study we try to elucidate the mechanism of Xiangqing anodyne spray (XQAS effects on acute soft-tissue injury (STI. Methods. Acute STI model was established by hammer blow in the rat hind leg muscle. Within 8 hours, instantly after modeling and per 2-hour interval repeated topical applications with or without XQAS, CP or IH ethanol extracts spray (CPS and IHS were performed, respectively; muscle swelling rate and inflammation-related biochemical parameters, muscle histological observation, and mRNA and protein expression were then examined. Results. XQAS dose-dependently suppressed STI-caused muscle swelling, proinflammatory mediator productions, and oxidative stress as well as severe pathological changes in the injured muscle tissue. Moreover, CPS mainly by blocking p38 activation while IHS majorly by blocking AKT activation led to cytoplastic IκBα degradation with NF-κB p65 translocated into the nucleus. There are synergistic effects between CP and IH components in the XQAS on preventing from acute STI with suppressing IκBα degradation, NF-κB p65 translocation, and subsequent inflammation and oxidative stress-related abnormality. Conclusion. Marked effects of XQAS on treating acute STI are ascribed to strong anti-inflammatory and antioxidative actions with a reasonable combination of CP active components, blocking p38-NF-κB pathway activated, and IH active components, blocking AKT-NF-κB pathway activated.

  13. Combining hydrologic and groundwater modelling to characterize a regional aquifer system within a rift setting (Gidabo River Basin, Main Ethiopian Rift)

    Science.gov (United States)

    Birk, Steffen; Mechal, Abraham; Wagner, Thomas; Dietzel, Martin; Leis, Albrecht; Winkler, Gerfried; Mogessie, Aberra

    2016-04-01

    heads measured in 72 wells. To account for the incomplete knowledge of the aquifer system several model set-ups differing in the number of transmissivity zones as well as in the implementation of fault zones, rivers, and model boundaries were evaluated using information criteria. The general pattern of the hydraulic-head distribution resulting from the plausible model set-ups agrees reasonably well with that obtained from the observations. Likewise the simulated baseflow is similar (though slightly higher) to that obtained by baseflow separation from measured discharge. The estimated transmissivity increases from the highland (in the order of 10-100 m²/day) toward the rift floor (in the order of 100-1000 m²/day). Although the rift-floor aquifers are mainly (65%) supplied by recharge from precipitation, groundwater flow from the highland (mountain block recharge) is found to provide a significant contribution (35%). At present, less than 1% of the groundwater flow is abstracted by pumping wells, suggesting a high potential for groundwater development both in the highland and the rift floor. With regard to the rift floor, potential effects of climate change on groundwater resources deserve further investigation, as the hydrological model suggests a high sensitivity of groundwater recharge to changes of precipitation and air temperature particularly within this part of the watershed.

  14. Development of a Probabilistic Tornado Wind Hazard Model for the Continental United States Volume I: Main Report

    International Nuclear Information System (INIS)

    Boissonnade, A; Hossain, Q; Kimball, J

    2000-01-01

    Since the mid-l980's, assessment of the wind and tornado risks at the Department of Energy (DOE) high and moderate hazard facilities has been based on the straight wind/tornado hazard curves given in UCRL-53526 (Coats, 1985). These curves were developed using a methodology that utilized a model, developed by McDonald, for severe winds at sub-tornado wind speeds and a separate model, developed by Fujita, for tornado wind speeds. For DOE sites not covered in UCRL-53526, wind and tornado hazard assessments are based on the criteria outlined in DOE-STD-1023-95 (DOE, 1996), utilizing the methodology in UCRL-53526; Subsequent to the publication of UCRL53526, in a study sponsored by the Nuclear Regulatory Commission (NRC), the Pacific Northwest Laboratory developed tornado wind hazard curves for the contiguous United States, NUREG/CR-4461 (Ramsdell, 1986). Because of the different modeling assumptions and underlying data used to develop the tornado wind information, the wind speeds at specified exceedance levels, at a given location, based on the methodology in UCRL-53526, are different than those based on the methodology in NUREG/CR-4461. In 1997, Lawrence Livermore National Laboratory (LLNL) was funded by the DOE to review the current methodologies for characterizing tornado wind hazards and to develop a state-of-the-art wind/tornado characterization methodology based on probabilistic hazard assessment techniques and current historical wind data. This report describes the process of developing the methodology and the database of relevant tornado information needed to implement the methodology. It also presents the tornado wind hazard curves obtained from the application of the method to DOE sites throughout the contiguous United States

  15. Analysis of the main dosimetric peak of Al2O3:C compounds with a model of interacting traps

    International Nuclear Information System (INIS)

    Ortega, F.; Marcazzó, J.; Molina, P.; Santiago, M.; Lester, M.; Henniger, J.; Caselli, E.

    2013-01-01

    The glow curve of Al 2 O 3 :C compounds has been analyzed by employing a model consisting of two active traps, thermally disconnected traps and one recombination centre. The analysis takes into account interaction among traps and the thermal quenching of the thermoluminescent emission. - Highlights: • Glow curves of Al 2 O 3 :C for two doses have been analysed taking into account interactions among traps. • The system of differential equations describing the kinetics has been uncoupled. • The new system of equations takes into account equations without derivatives. • The algorithm used will not become stiff. • The kinetics parameters obtained do not depend on the dose

  16. Modeling Reaction Control System Effects on Mars Odyssey

    National Research Council Canada - National Science Library

    Hanna, Jill

    2002-01-01

    ...) simulations to determine rotational motion of the spacecraft. The main objective of this study was to assess the reaction control system models and their effects on the atmospheric flight of Odyssey...

  17. Investigation of the effect of solubility increase at the main absorption site on bioavailability of BCS class II drug (risperidone) using liquisolid technique.

    Science.gov (United States)

    Khames, Ahmed

    2017-11-01

    BCS class II drugs usually suffer inadequate bioavailability as dissolution step is the absorption rate limiting step. In this work, the effect of solubility increase at the main absorption site for these drugs was investigated using risperidone as a drug model. Liquisolid technique was applied to prepare risperidone per-oral tablets of high dissolution rate at intestinal pH (6.8) using versatile nonionic surfactants of high solubilizing ability [Transcutol HP, Labrasol and Labrasol/Labrafil (1:1) mixture] as liquid vehicles at different drug concentrations (10-30%) and fixed (R). The prepared liquisolid tablets were fully evaluated and the dissolution rate at pH 6.8 was investigated. The formulae that showed significantly different release rate were selected and subjected to mathematical modeling using DE 25 , MDT and similarity factor (f2). Depending on mathematical modeling results, formula of higher dissolution rate was subjected to solid state characterization using differential scanning calorimetric (DSC), infrared spectroscopy (IR) and X-ray diffraction (XRD). Finally, the drug bioavailability was studied in comparison to conventional tablets in rabbits. Results showed that liquisolid tablet prepared using Labrasol/Labrafil (1:1) mixture as liquid vehicle containing 10% risperidone is a compatible formula with law drug crystallinity and higher dissolution rate (100% in 25 min). The drug bioavailability was significantly increased in comparison to the conventional tablets (1441.711 μg h/mL and 137.518 μg/mL in comparison to 321.011 μg h/mL and 38.673 μg/mL for AUC and Cp max , respectively). This led to the conclusion that liquisolid technique was efficiently improved drug solubility and solubility increase of BCS class II drugs at their main absorption site significantly increases their bioavailability.

  18. Emission of hydrogen sulfide (H2S) at a waterfall in a sewer: study of main factors affecting H2S emission and modeling approaches.

    Science.gov (United States)

    Jung, Daniel; Hatrait, Laetitia; Gouello, Julien; Ponthieux, Arnaud; Parez, Vincent; Renner, Christophe

    2017-11-01

    Hydrogen sulfide (H 2 S) represents one of the main odorant gases emitted from sewer networks. A mathematical model can be a fast and low-cost tool for estimating its emission. This study investigates two approaches to modeling H 2 S gas transfer at a waterfall in a discharge manhole. The first approach is based on an adaptation of oxygen models for H 2 S emission at a waterfall and the second consists of a new model. An experimental set-up and a statistical data analysis allowed the main factors affecting H 2 S emission to be studied. A new model of the emission kinetics was developed using linear regression and taking into account H 2 S liquid concentration, waterfall height and fluid velocity at the outlet pipe of a rising main. Its prediction interval was estimated by the residual standard deviation (15.6%) up to a rate of 2.3 g H 2 S·h -1 . Finally, data coming from four sampling campaigns on sewer networks were used to perform simulations and compare predictions of all developed models.

  19. Investigation of natural levels of radon-222 in groundwater in Maine for assessment of related health effects

    International Nuclear Information System (INIS)

    Hess, C.T.; Casparius, R.E.; Norton, S.A.; Brutsaert, W.F.

    1980-01-01

    We have used an inexpensive radon ( 222 Rn) measurement method using liquid scintillation counting to remeasure potable water from 10 sites near Raymond, Maine, to determine the accuracy and reproducibility of earlier measurements. Duplication or triplication of samples shows a high degree of reproducibility for the liquid scintillation method. A hypothesis emerged from analysis of the measured values of 222 Rn near Raymond, Maine, that high values (50,000 to 200,000 pCi/liter) are associated with granite. This was shown to be correct for several large areas of granite such as the Sebago, Lucern, Waldo, and Waldoboro granites. The presence of high 222 Rn concentrations in granite areas hundreds of kilometers from the Raymond area shows that the high 222 Rn levels in water are a statewide and perhaps a regional problem rather than a western Maine problem

  20. Associations of social support and stress with postpartum maternal mental health symptoms: Main effects, moderation, and mediation.

    Science.gov (United States)

    Schwab-Reese, Laura M; Schafer, Ellen J; Ashida, Sato

    2017-07-01

    Poor maternal mental health during the postpartum period can have significant effects on the health of mothers, infants, and families. The findings from cross-sectional studies suggest that stress and social support are related to maternal mental health. This study contributes to the literature through the use of longitudinal data, and examines moderation and mediation among these factors. In 2012-2013, mothers completed surveys assessing stress, social support, and depressive and anxiety symptoms following birth (n = 125), and 3 months (n = 110) and 6 months (n = 99) after birth. The authors examined temporal associations, moderation, and mediation of social support on the relationship between stress and postpartum depressive and anxiety symptoms using modified Poisson regression models and the counterfactual approach to mediation. Current levels of stress and social support were associated with depressive and anxiety symptoms, both independently and when considered together at multiple time points. Social support did not strongly moderate or mediate the relationships between stress and maternal mental health. Interventions to reduce current perceptions of stress and increase social support for mothers during the postpartum period may help improve maternal mental health symptoms. Efforts are needed to assess the current needs of mothers continuously.

  1. Effect of 3-year education in the Main Fire Service School on the fitness level of students

    Directory of Open Access Journals (Sweden)

    Andrzej Tomczak

    2017-12-01

    Speed endurance (anaerobic-aerobic is a capability which decreased among the students in the subsequent years. Because this capability highly correlates with activities that a fire-fighter will perform during rescue operations, it should be treated as a matter of priority during physical education classes in the Main Fire Service School.

  2. Impact of 900 MHz electromagnetic field exposure on main male reproductive hormone levels: a Rattus norvegicus model

    Science.gov (United States)

    Sepehrimanesh, Masood; Saeb, Mehdi; Nazifi, Saeed; Kazemipour, Nasrin; Jelodar, Gholamali; Saeb, Saeedeh

    2014-09-01

    This work analyzes the effects of radiofrequency-electromagnetic field (RF-EMF) exposure on the reproductive system of male rats, assessed by measuring circulating levels of FSH, LH, inhibin B, activin B, prolactin, and testosterone. Twenty adult male Sprague-Dawley rats (180 ± 10 g) were exposed to 900 MHz RF-EMF in four equal separated groups. The duration of exposure was 1, 2, and 4 h/day over a period of 30 days and sham-exposed animals were kept under the same environmental conditions as the exposed group except with no RF-EMF exposure. Before the exposure, at 15 and 30 days of exposure, determination of the abovementioned hormone levels was performed using ELISA. At the end of the experiment, FSH and LH values of the long time exposure (LTE) group were significantly higher than the sham-exposed group ( p reproductive hormone levels are disturbed as a result of RF-EMF exposure and it may possibly affect reproductive functions. However, testosterone and inhibin B concentrations as a fertility marker and spermatogenesis were decreased significantly.

  3. RESEARCH OF THE HIGH HARMONICS INDIVIDUAL BLADE CONTROL EFFECT ON VIBRATIONS CAUSED BY THE HELICOPTER MAIN ROTOR THRUST

    Directory of Open Access Journals (Sweden)

    2016-01-01

    Full Text Available The paper presents numerical results analysis of main rotor vibration due to helicopter main rotor thrust pulsation.The calculation method, the object of research and numerical research results with the aim to reduce the amplitude of the vibrations transmitted to the hub from the helicopters main rotor by the individual blade control in azimuth by the installation angle of blades cyclic changes are set out in the article. The individual blades control law for a five-blade main rotor based on the blade frequencies is made. It allows reducing the vibration from thrust. Research takes into account the main rotor including and excluding the blade flapping motion. The minimal vibrations regime is identified.Numerical study of variable loads caused by unsteady flow around the main rotor blades at high relative speeds of flight, which transmitted to the rotor hub, is made. The scheme of a thin lifting surface and the rotor vortex theory are used for simulation of the aerodynamic loads on blades. Non - uniform loads caused by the thrust, decomposed on the blade harmonic and its overtones. The largest values of deviation from the mean amplitude thrust are received. The analysis of variable loads with a traditional control system is made. Algorithms of higher harmonics individual blade control capable of reducing the thrust pulsation under the average value of thrust are developed.Numerical research shows that individual blade control of high harmonics reduces variable loads. The necessary change in the blade installation is about ± 0,2 degree that corresponds to the maximum displacement of the additional con- trol stick is about 1 mm.To receive the overall picture is necessary to consider all six components of forces and moments. Control law with own constants will obtained for each of them. It is supposed, that each of six individual blade control laws have an impact on other components. Thus, the problem reduces to the optimization issue. The

  4. Bio-effectiveness of the main flavonoids of Achillea millefolium in the pathophysiology of neurodegenerative disorders- a review

    Directory of Open Access Journals (Sweden)

    Fatemeh Ayoobi

    2017-06-01

    Full Text Available The Achillea millefolium L. (Yarrow is a common herb which is widely being used, worldwide. Achillea is being used for treatment of many disorders since centuries. It is considered safe for supplemental use and flavonoids such as kaempferol, luteolin and apigenin are of main constituents present in Achillea. Most of both antioxidant and anti-inflammatory properties of this herb have been attributed to its flavonoid content. Oxidative and inflammatory processes play important roles in pathogenesis of neurodegenerative diseases. Present review was aimed to review the latest literature evidences regarding application of Achillea and/or its three main flavonoid constituents on epilepsy, Alzheimer's disease, multiple sclerosis, Parkinson's disease and stroke.

  5. Studies of the quality and cost-effectiveness of a novel conceptof open-die forged powerplant main shaft

    Directory of Open Access Journals (Sweden)

    P. Skubisz

    2015-04-01

    Full Text Available An innovatory concept of open-die forging of windmill main shaft is described. Comparative study of the new technology based on the concept of cogging hollow shaft on mandrel featuring material savings and higher quality of a finished part versus traditional production chain of this component is presented, indicating benefits and technological setbacks of industrial implementation. Results of industrial sampling aided with numerical simulation form guidelines for technological realization.

  6. Evolution models of helium white dwarf-main-sequence star merger remnants: the mass distribution of single low-mass white dwarfs

    Science.gov (United States)

    Zhang, Xianfei; Hall, Philip D.; Jeffery, C. Simon; Bi, Shaolan

    2018-02-01

    It is not known how single white dwarfs with masses less than 0.5Msolar -- low-mass white dwarfs -- are formed. One way in which such a white dwarf might be formed is after the merger of a helium-core white dwarf with a main-sequence star that produces a red giant branch star and fails to ignite helium. We use a stellar-evolution code to compute models of the remnants of these mergers and find a relation between the pre-merger masses and the final white dwarf mass. Combining our results with a model population, we predict that the mass distribution of single low-mass white dwarfs formed through this channel spans the range 0.37 to 0.5Msolar and peaks between 0.45 and 0.46Msolar. Helium white dwarf--main-sequence star mergers can also lead to the formation of single helium white dwarfs with masses up to 0.51Msolar. In our model the Galactic formation rate of single low-mass white dwarfs through this channel is about 8.7X10^-3yr^-1. Comparing our models with observations, we find that the majority of single low-mass white dwarfs (<0.5Msolar) are formed from helium white dwarf--main-sequence star mergers, at a rate which is about $2$ per cent of the total white dwarf formation rate.

  7. Kriging with mixed effects models

    Directory of Open Access Journals (Sweden)

    Alessio Pollice

    2007-10-01

    Full Text Available In this paper the effectiveness of the use of mixed effects models for estimation and prediction purposes in spatial statistics for continuous data is reviewed in the classical and Bayesian frameworks. A case study on agricultural data is also provided.

  8. Development and quantitative effect estimation of an integrated decision support system to aid operator's cognitive activities for NPP advanced main control rooms

    International Nuclear Information System (INIS)

    Lee, Seung Jun

    2007-02-01

    As digital and computer technologies have grown, human-machine interfaces (HMIs) have evolved. In safety critical systems, especially in nuclear power plants (NPPs), HMIs are important for reducing operational costs, for reducing the number of necessary operators, and for reducing the probability of accident occurrence. Efforts have been made to improve main control room (MCR) interface design and to develop automation or support systems to ensure convenient operation and maintenance. In this paper, an integrated decision support system to aid the cognitive activities of operators is proposed for advanced MCRs in future NPPs. The proposed system supports not merely a particular task, but also the entire operation process based on a human cognitive process model. It supports the operator's entire cognitive process by integrating decision support systems that support each cognitive activity. In this paper, the operator's operation processes are analyzed based on a human cognitive process model and appropriate support systems that support each activity of the human cognitive process are suggested. Two decision support systems were developed in this paper. The first one is the fault diagnosis advisory system (FDAS) which detects faults and diagnoses them. The FDAS provides a list of possible faults and expected causes to operators. It was implemented using two kinds of neural networks for more reliable diagnosis results. The second system is the multifunctional operator support system for operation guidance, which includes the FDAS and the operation guidance system. The operation guidance system is to prevent operator's commission errors and omission errors. Furthermore, the effect of the proposed system was estimated because to evaluate decision support systems in order to validate their efficiency is as important as to design highly reliable decision support systems. The effect estimations were performed theoretically and experimentally. The Bayesian

  9. SagE induces highly effective protective immunity against Streptococcus iniae mainly through an immunogenic domain in the extracellular region.

    Science.gov (United States)

    Sun, Yun; Sun, Li; Xing, Ming-qing; Liu, Chun-sheng; Hu, Yong-hua

    2013-11-12

    Streptococcus iniae is a Gram-positive bacterium and a severe pathogen of a wide range of farmed fish. S. iniae possesses a virulence-associated streptolysin S cluster composed of several components, one of which is SagE. SagE a transmembrane protein with one major extracellular region named ECR. This study aimed to develop a SagE-based DNA candidate vaccine against streptococcosis and examine the immunoprotective mechanism of the vaccine. We constructed a DNA vaccine, pSagE, based on the sagE gene and examined its immunological property in a Japanese flounder (Paralichthys olivaceus) model. The results showed that at 7 days post-vaccination, expression of SagE at transcription and translation levels was detected in the tissues of the vaccinated fish. After challenge with S. iniae at one and two months post-vaccination, pSagE-vaccinated fish exhibited relative percent survival (RPS) of 95% and 88% respectively. Immunological analysis showed that (i) pSagE significantly upregulated the expression of a wide range of immune genes, (ii) pSagE induced the production of specific serum antibodies that bound whole-cell S. iniae, and (iii) treatment of S. iniae with pSagE-induced antibodies blocked bacterial invasion of host cells. To localize the immunoprotective domain of SagE, the ECR-expressing DNA vaccine pSagEECR was constructed. Immunization analysis showed that flounder vaccinated with pSagEECR exhibited a RPS of 68%, and that pSagEECR induced serum antibody production and immune gene expression in a manner similar to, though to lower magnitudes than, those induced by pSagE. We in this study developed a DNA vaccine, pSagE, which induces highly protective immunity against S. iniae. The protective effect of pSagE is probably due to its ability to elicit systemic immune response, in particular that of the humoral branch, which leads to production of specific serum antibodies that impair bacterial infection. These results add insights to the immunoprotective mechanism

  10. Simulation of the Quantity, Variability, and Timing of Streamflow in the Dennys River Basin, Maine, by Use of a Precipitation-Runoff Watershed Model

    Science.gov (United States)

    Dudley, Robert W.

    2008-01-01

    The U.S. Geological Survey (USGS), in cooperation with the Maine Department of Marine Resources Bureau of Sea Run Fisheries and Habitat, began a study in 2004 to characterize the quantity, variability, and timing of streamflow in the Dennys River. The study included a synoptic summary of historical streamflow data at a long-term streamflow gage, collecting data from an additional four short-term streamflow gages, and the development and evaluation of a distributed-parameter watershed model for the Dennys River Basin. The watershed model used in this investigation was the USGS Precipitation-Runoff Modeling System (PRMS). The Geographic Information System (GIS) Weasel was used to delineate the Dennys River Basin and subbasins and derive parameters for their physical geographic features. Calibration of the models used in this investigation involved a four-step procedure in which model output was evaluated against four calibration data sets using computed objective functions for solar radiation, potential evapotranspiration, annual and seasonal water budgets, and daily streamflows. The calibration procedure involved thousands of model runs and was carried out using the USGS software application Luca (Let us calibrate). Luca uses the Shuffled Complex Evolution (SCE) global search algorithm to calibrate the model parameters. The SCE method reliably produces satisfactory solutions for large, complex optimization problems. The primary calibration effort went into the Dennys main stem watershed model. Calibrated parameter values obtained for the Dennys main stem model were transferred to the Cathance Stream model, and a similar four-step SCE calibration procedure was performed; this effort was undertaken to determine the potential to transfer modeling information to a nearby basin in the same region. The calibrated Dennys main stem watershed model performed with Nash-Sutcliffe efficiency (NSE) statistic values for the calibration period and evaluation period of 0.79 and 0

  11. Evaluation of acoustic resonance at branch section in main steam line. Part 1. Effects of steam wetness on acoustic resonance

    International Nuclear Information System (INIS)

    Uchiyama, Yuta; Morita, Ryo

    2011-01-01

    The power uprating of the nuclear power plant (NPP) is conducted in United States, EU countries and so on, and also is planned in Japan. However, the degradation phenomena such as flow-induced vibration and wall thinning may increase or expose in the power uprate condition. In U.S. NPP, the dryer had been damaged by high cycle fatigue due to acoustic-induced vibration under a 17% extended power uprating (EPU) condition. This is caused by acoustic resonance at the stub pipes of safety relief valves (SRVs) in the main steam lines (MSL). Increased velocity by uprating excites the pressure fluctuations and makes large amplitude resonance. To evaluate the acoustic resonance at the stub pipes of SRVs in actual BWR, it is necessary to clarify the acoustic characteristics in steam flow. Although there are several previous studies about acoustic resonance, most of them are not steam flow but air flow. Therefore in this study, to investigate the acoustic characteristics in steam flow, we conducted steam flow experiments in each dry and wet steam conditions, and also nearly saturated condition. We measured pressure fluctuation at the top of the single stub pipe and in main steam piping. As a result, acoustic resonance in dry steam flow could be evaluated as same as that in air flow. It is clarified that resonance amplitude of fluctuating pressure at the top of the stub pipe in wet steam was reduced to one-tenth compared with that in dry. (author)

  12. A main sequence for quasars

    Science.gov (United States)

    Marziani, Paola; Dultzin, Deborah; Sulentic, Jack W.; Del Olmo, Ascensión; Negrete, C. A.; Martínez-Aldama, Mary L.; D'Onofrio, Mauro; Bon, Edi; Bon, Natasa; Stirpe, Giovanna M.

    2018-03-01

    The last 25 years saw a major step forward in the analysis of optical and UV spectroscopic data of large quasar samples. Multivariate statistical approaches have led to the definition of systematic trends in observational properties that are the basis of physical and dynamical modeling of quasar structure. We discuss the empirical correlates of the so-called “main sequence” associated with the quasar Eigenvector 1, its governing physical parameters and several implications on our view of the quasar structure, as well as some luminosity effects associated with the virialized component of the line emitting regions. We also briefly discuss quasars in a segment of the main sequence that includes the strongest FeII emitters. These sources show a small dispersion around a well-defined Eddington ratio value, a property which makes them potential Eddington standard candles.

  13. A Main Sequence for Quasars

    Directory of Open Access Journals (Sweden)

    Paola Marziani

    2018-03-01

    Full Text Available The last 25 years saw a major step forward in the analysis of optical and UV spectroscopic data of large quasar samples. Multivariate statistical approaches have led to the definition of systematic trends in observational properties that are the basis of physical and dynamical modeling of quasar structure. We discuss the empirical correlates of the so-called “main sequence” associated with the quasar Eigenvector 1, its governing physical parameters and several implications on our view of the quasar structure, as well as some luminosity effects associated with the virialized component of the line emitting regions. We also briefly discuss quasars in a segment of the main sequence that includes the strongest FeII emitters. These sources show a small dispersion around a well-defined Eddington ratio value, a property which makes them potential Eddington standard candles.

  14. Parameterization of the InVEST Crop Pollination Model to spatially predict abundance of wild blueberry (Vaccinium angustifolium Aiton) native bee pollinators in Maine, USA

    Science.gov (United States)

    Groff, Shannon C.; Loftin, Cynthia S.; Drummond, Frank; Bushmann, Sara; McGill, Brian J.

    2016-01-01

    Non-native honeybees historically have been managed for crop pollination, however, recent population declines draw attention to pollination services provided by native bees. We applied the InVEST Crop Pollination model, developed to predict native bee abundance from habitat resources, in Maine's wild blueberry crop landscape. We evaluated model performance with parameters informed by four approaches: 1) expert opinion; 2) sensitivity analysis; 3) sensitivity analysis informed model optimization; and, 4) simulated annealing (uninformed) model optimization. Uninformed optimization improved model performance by 29% compared to expert opinion-informed model, while sensitivity-analysis informed optimization improved model performance by 54%. This suggests that expert opinion may not result in the best parameter values for the InVEST model. The proportion of deciduous/mixed forest within 2000 m of a blueberry field also reliably predicted native bee abundance in blueberry fields, however, the InVEST model provides an efficient tool to estimate bee abundance beyond the field perimeter.

  15. Development and application of an entrainment model for the PWR U-tube steam generators for main steam line break analysis

    International Nuclear Information System (INIS)

    Song, Dong-Soo; Park, Young-Chan

    2004-01-01

    The purpose of this paper is to present the analyses that were performed to develop and use an entrainment model for pressurized water reactor U-tube steam generators (SG) for main steam line break (MSLB) analyses. The entrainment model was developed using the RETRAN-3D computer program, and the model was benchmarked against experimental data of moisture carryover during a simulated MSLB accident. The application methodology was also developed to incorporate into the MSLB mass and energy release calculations for Kori Unit 1. This methodology utilizes LOFTRAN and RETRAN-3D codes in an iterative sequence of cases in which the LOFTRAN nuclear steam supply system model provides boundary conditions for the RETRAN-3D broken loop steam generator model, and the RETRAN-3D model provides the entrainment data that is input back into the LOFTRAN model. FORTRAN programs were developed to facilitate the sequencing of these iterative calculations. As a result of applying the entrainment model to Kori Unit 1, the temperature calculated inside Containment during MSLB accident using the CONTEMP-LT computer program decreased by about 25degC. Consequently this entrainment model provides a significant benefit by decreasing the temperature envelop for environment qualification as well as decreasing the peak Containment pressure. (author)

  16. Automation based on knowledge modeling theory and its applications in engine diagnostic systems using Space Shuttle Main Engine vibrational data. M.S. Thesis

    Science.gov (United States)

    Kim, Jonnathan H.

    1995-01-01

    Humans can perform many complicated tasks without explicit rules. This inherent and advantageous capability becomes a hurdle when a task is to be automated. Modern computers and numerical calculations require explicit rules and discrete numerical values. In order to bridge the gap between human knowledge and automating tools, a knowledge model is proposed. Knowledge modeling techniques are discussed and utilized to automate a labor and time intensive task of detecting anomalous bearing wear patterns in the Space Shuttle Main Engine (SSME) High Pressure Oxygen Turbopump (HPOTP).

  17. Effective modelling of acoustofluidic devices

    DEFF Research Database (Denmark)

    Ley, Mikkel Wennemoes Hvitfeld

    , and 3) acoustic streaming patterns in the devices considered in model 2). 1) We derive an effective model for numerical studies of hydrodynamic particle-particle interactions in microfluidic high-concentration suspensions. A suspension of microparticles placed in a microfluidic channel and influenced......, and of the momentum transfer between the particles and the suspension. 2) We derive a full 3D numerical model for the coupled acoustic fields in mm-sized water-filled glass capillaries, calculating pressure field in the liquid coupled to the displacement field of the glass channel, taking into account mixed standing...... for the acoustic field in glass capillary devices derived in 2), we make an effective model for calculating the acoustic streaming velocity in 3D. To do this, we use recent analytical results that allows calculation of the acoustic streaming field resulting from channel-wall oscillations in any direction...

  18. Integrating urban recharge uncertainty into standard groundwater modeling practice: A case study on water main break predictions for the Barton Springs segment of the Edwards Aquifer, Austin, Texas

    Science.gov (United States)

    Sinner, K.; Teasley, R. L.

    2016-12-01

    Groundwater models serve as integral tools for understanding flow processes and informing stakeholders and policy makers in management decisions. Historically, these models tended towards a deterministic nature, relying on historical data to predict and inform future decisions based on model outputs. This research works towards developing a stochastic method of modeling recharge inputs from pipe main break predictions in an existing groundwater model, which subsequently generates desired outputs incorporating future uncertainty rather than deterministic data. The case study for this research is the Barton Springs segment of the Edwards Aquifer near Austin, Texas. Researchers and water resource professionals have modeled the Edwards Aquifer for decades due to its high water quality, fragile ecosystem, and stakeholder interest. The original case study and model that this research is built upon was developed as a co-design problem with regional stakeholders and the model outcomes are generated specifically for communication with policy makers and managers. Recently, research in the Barton Springs segment demonstrated a significant contribution of urban, or anthropogenic, recharge to the aquifer, particularly during dry period, using deterministic data sets. Due to social and ecological importance of urban water loss to recharge, this study develops an evaluation method to help predicted pipe breaks and their related recharge contribution within the Barton Springs segment of the Edwards Aquifer. To benefit groundwater management decision processes, the performance measures captured in the model results, such as springflow, head levels, storage, and others, were determined by previous work in elicitation of problem framing to determine stakeholder interests and concerns. The results of the previous deterministic model and the stochastic model are compared to determine gains to stakeholder knowledge through the additional modeling

  19. Effects of 3,4-methylenedioxymethamphetamine (MDMA) and its main metabolites on cardiovascular function in conscious rats.

    Science.gov (United States)

    Schindler, Charles W; Thorndike, Eric B; Blough, Bruce E; Tella, Srihari R; Goldberg, Steven R; Baumann, Michael H

    2014-01-01

    The cardiovascular effects produced by 3,4-methylenedioxymethamphetamine (MDMA; 'Ecstasy') contribute to its acute toxicity, but the potential role of its metabolites in these cardiovascular effects is not known. Here we examined the effects of MDMA metabolites on cardiovascular function in rats. Radiotelemetry was employed to evaluate the effects of s.c. administration of racemic MDMA and its phase I metabolites on BP, heart rate (HR) and locomotor activity in conscious male rats. MDMA (1-20 mg·kg(-1)) produced dose-related increases in BP, HR and activity. The peak effects on HR occurred at a lower dose than peak effects on BP or activity. The N-demethylated metabolite, 3,4-methylenedioxyamphetamine (MDA), produced effects that mimicked those of MDMA. The metabolite 3,4-dihydroxymethamphetamine (HHMA; 1-10 mg·kg(-1)) increased HR more potently and to a greater extent than MDMA, whereas 3,4-dihydroxyamphetamine (HHA) increased HR, but to a lesser extent than HHMA. Neither dihydroxy metabolite altered motor activity. The metabolites 4-hydroxy-3-methoxymethamphetamine (HMMA) and 4-hydroxy-3-methoxyamphetamine (HMA) did not affect any of the parameters measured. The tachycardia produced by MDMA and HHMA was blocked by the β-adrenoceptor antagonist propranolol. Our results demonstrate that HHMA may contribute significantly to the cardiovascular effects of MDMA in vivo. As such, determining the molecular mechanism of action of HHMA and the other hydroxyl metabolites of MDMA warrants further study. Published 2013. This article is a U.S. Government work and is in the public domain in the USA.

  20. The effect of small specimen volume on the deformation of Zircaloy-4 PWR cladding under mainly convective cooling by steam

    International Nuclear Information System (INIS)

    Oakden, M.M.; Reynolds, A.E.

    1983-01-01

    Creep rupture tests were performed in flowing steam on single rod specimens of 17x17 type PWR Zircaloy-4 cladding 460 mm long. They were tested at temperatures between 640 deg.C and 985 deg.C with internal pressures in the range 1.00-9.65 MPa (gauge) (145-1400 lb/in 2 ). The internal free volume was limited to 2.9 ml. Axially extended 'carrot' shaped deformations were produced, the range of temperatures and pressures over which these occurred was found to be similar to that observed in previous tests conducted with a much larger free volume. The main result of limiting the internal volume was that straining of the specimens was accompanied by a more rapid drop in the internal pressure than occurred previously, and which reduced the extent of the deformation compared with that seen in the earlier work. However, diametral strains in excess of 33% were observed which would result in mechanical interaction of neighbouring bulges if this occurred in a multi-rod array. (author)

  1. Main conditions and effectiveness of gas fuel use for powering of dual fuel IC self-ignition engine

    Directory of Open Access Journals (Sweden)

    Stefan POSTRZEDNIK

    2015-09-01

    Full Text Available Internal combustion engines are fuelled mostly with liquid fuels (gasoline, diesel. Nowadays the gaseous fuels are applied as driving fuel of combustion engines. In case of spark ignition engines the liquid fuel (petrol can be totally replaced by the gas fuels. This possibility in case of compression engines is essentially restricted through the higher self-ignition temperatures of the combustible gases in comparison to classical diesel oil. Solution if this problem can be achieved by using of the dual fuel system, where for ignition of the prepared fuel gas - air mixture a specified amount of the liquid fuel (diesel oil should be additionally injected into the combustion chamber. For assurance that the combustion process proceeds without mistakes and completely, some basic conditions should be satisfied. In the frame of this work, three main aspects of this problem are taken into account: a. filling efficiency of the engine, b. stoichiometry of the combustion, c. performance of mechanical parameters (torque, power. A complex analysis of these conditions has been done and some achieved important results are presented in the paper.

  2. Effect of main injection timing for controlling the combustion phasing of a homogeneous charge compression ignition engine using a new dual injection strategy

    International Nuclear Information System (INIS)

    Das, Pranab; Subbarao, P.M.V.; Subrahmanyam, J.P.

    2015-01-01

    Highlights: • A new dual injection concept is developed by minimum geometry modification. • The occurrence of combustion parameters strongly depend on main injection timing. • At higher load, premixed equivalence ratio dominates over main injection timing. • Retarded of main injection timing tends to retard combustion phasing. • Slightly retarded main injection timing is recommended to avoid intense knocking. - Abstract: Homogeneous charge compression ignition combustion of diesel fuel is implemented using a novel dual injection strategy. A new experimental technique is developed to modify a single cylinder direct injection diesel engine to run on homogeneous combustion mode. Effect of main injection timing is investigated covering a range from 26 to 8 crank angle degrees before top dead center with an interval of 3°. Retarded main injection timing is identified as a control strategy for delaying combustion phasing and a means of controlled combustion phasing of direct injection homogeneous charge compression ignition combustion. Two load conditions were investigated and it was observed that at higher load, start of combustion depends more on fuel air equivalence ratio than main injection timing, whereas at low load, it significantly varies with varying main injection timing. Significant improvements in smoke and oxides of nitrogen emissions are observed when compared with the baseline conventional combustion. By studying different combustion parameters, it is observed that there is an improvement in performance and emissions with marginal loss in thermal efficiency when the main injection timing is 20° before top dead center. This is identified as the optimum main injection timing for such homogeneous combustion under the same operating condition

  3. Conflict-Specific Aging Effects Mainly Manifest in Early Information Processing Stages-An ERP Study with Different Conflict Types.

    Science.gov (United States)

    Korsch, Margarethe; Frühholz, Sascha; Herrmann, Manfred

    2016-01-01

    Aging is usually accompanied by alterations of cognitive control functions such as conflict processing. Recent research suggests that aging effects on cognitive control seem to vary with degree and source of conflict, and conflict specific aging effects on performance measures as well as neural activation patterns have been shown. However, there is sparse information whether and how aging affects different stages of conflict processing as indicated by event related potentials (ERPs) such as the P2, N2 and P3 components. In the present study, 19 young and 23 elderly adults performed a combined Flanker conflict and stimulus-response-conflict (SRC) task. Analysis of the reaction times (RTs) revealed an increased SRC related conflict effect in elderly. ERP analysis furthermore demonstrated an age-related increase of the P2 amplitude in response to the SRC task. In addition, elderly adults exhibited an increased P3 amplitude modulation induced by incongruent SRC and Flanker conflict trials.

  4. ACTIVE GALACTIC NUCLEI AS MAIN CONTRIBUTORS TO THE ULTRAVIOLET IONIZING EMISSIVITY AT HIGH REDSHIFTS: PREDICTIONS FROM A Λ-CDM MODEL WITH LINKED AGN/GALAXY EVOLUTION

    International Nuclear Information System (INIS)

    Giallongo, E.; Menci, N.; Fiore, F.; Castellano, M.; Fontana, A.; Grazian, A.; Pentericci, L.

    2012-01-01

    We have evaluated the contribution of the active galactic nuclei (AGN) population to the ionization history of the universe based on a semi-analytic model of galaxy formation and evolution in the cold dark matter cosmological scenario. The model connects the growth of black holes and of the ensuing AGN activity to galaxy interactions. In the model we have included a self-consistent physical description of the escape of ionizing UV photons; this is based on the blast-wave model for the AGN feedback we developed in a previous paper to explain the distribution of hydrogen column densities in AGNs of various redshifts and luminosities, due to absorption by the host galaxy gas. The model predicts UV luminosity functions for AGNs that are in good agreement with those derived from the observations especially at low and intermediate redshifts (z ∼ 3). At higher redshifts (z > 5), the model tends to overestimate the data at faint luminosities. Critical biases in both the data and in the model are discussed to explain such apparent discrepancies. The predicted hydrogen photoionization rate as a function of redshift is found to be consistent with that derived from the observations. All of the above suggests that we should reconsider the role of the AGNs as the main driver of the ionization history of the universe.

  5. Stochastic strong motion generation using slip model of 21 and 22 May 1960 mega-thrust earthquakes in the main cities of Central-South Chile

    Science.gov (United States)

    Ruiz, S.; Ojeda, J.; DelCampo, F., Sr.; Pasten, C., Sr.; Otarola, C., Sr.; Silva, R., Sr.

    2017-12-01

    In May 1960 took place the most unusual seismic sequence registered instrumentally. The Mw 8.1, Concepción earthquake occurred May, 21, 1960. The aftershocks of this event apparently migrated to the south-east, and the Mw 9.5, Valdivia mega-earthquake occurred after 33 hours. The structural damage produced by both events is not larger than other earthquakes in Chile and lower than crustal earthquakes of smaller magnitude. The damage was located in the sites with shallow soil layers of low shear wave velocity (Vs). However, no seismological station recorded this sequence. For that reason, we generate synthetic acceleration times histories for strong motion in the main cities affected by these events. We use 155 points of vertical surface displacements recopiled by Plafker and Savage in 1968, and considering the observations of this authors and local residents we separated the uplift and subsidence information associated to the first earthquake Mw 8.1 and the second mega-earthquake Mw 9.5. We consider the elastic deformation propagation, assume realist lithosphere geometry, and compute a Bayesian method that maximizes the probability density a posteriori to obtain the slip distribution. Subsequently, we use a stochastic method of generation of strong motion considering the finite fault model obtained for both earthquakes. We considered the incidence angle of ray to the surface, free surface effect and energy partition for P, SV and SH waves, dynamic corner frequency and the influence of site effect. The results show that the earthquake Mw 8.1 occurred down-dip the slab, the strong motion records are similar to other Chilean earthquake like Tocopilla Mw 7.7 (2007). For the Mw 9.5 earthquake we obtain synthetic acceleration time histories with PGA values around 0.8 g in cities near to the maximum asperity or that have low velocity soil layers. This allows us to conclude that strong motion records have important influence of the shallow soil deposits. These records

  6. Cost-effectiveness of trastuzumab in metastatic breast cancer: mainly a matter of price in the EU?

    Science.gov (United States)

    Garattini, Livio; van de Vooren, Katelijne; Curto, Alessandro

    2015-02-01

    Trastuzumab (TR), a monoclonal antibody approved by EMA in 2000 and one of the first examples of "targeted therapy", is indicated to treat human epidermal growth factor receptor 2 (HER2) positive breast cancer. TR, whose patent will expire in 2015 in Europe, has been judged positively for reimbursement by most public authorities in the EU. Here we critically review the existing evidence on TR in metastatic breast cancer (MBC), in line with the multidisciplinary health technology assessment (HTA) approach, to assess whether the existing evidence supports TR positive reimbursement decisions taken in MBC by EU health authorities. We did a literature search for the main HTA topics (efficacy, quality of life and ethics) on the PubMed international database (2000-2013). Then, we did a specific literature search to select the full economic evaluations (FEEs) conducted in EU countries focused on TR as first-line innovative therapy in MBC. We retrieved scant evidence in the literature to support TR reimbursement in MBC. We found only two clinical trials and their results were unclear because of the large proportion of patients who crossed over. Moreover, the quality of methods was poor in all four European FEEs selected. This example of HTA exercise on a mature monoclonal antibody in a specific indication casts doubts on how often the reimbursement decisions taken by EU health authorities in emotional pathologies like cancer are rational. These decisions should at least be reconsidered periodically on the basis of the latest evidence. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  7. Effects of Swertia japonica extract and its main compound swertiamarin on gastric emptying and gastrointestinal motility in mice.

    Science.gov (United States)

    Kimura, Yoshiyuki; Sumiyoshi, Maho

    2011-09-01

    The Swertia japonica is used clinically as a remedy for gastrointestinal symptoms in Japan. We examined the effects of a S. japonica and swertiamarin on gastric emptying and gastrointestinal motility in atropine-, dopamine-, and 5-hydroxytryptamine (5-HT)-treated mice. All three preparations inhibited reductions in gastric emptying and gastrointestinal motility induced by dopamine (1mg/kg, intraperitoneal injection, ip). Neither the powder, swertiamarin, nor itopride had any effect on the reductions in gastric emptying and gastrointestinal motility caused by 5-HT (4 mg/kg, ip). These findings suggest that the powder and swertiamarin stimulate gastric emptying and gastrointestinal motility by inhibiting the dopamine D(2) receptor. Copyright © 2011 Elsevier B.V. All rights reserved.

  8. Estimation of placental and lactational transfer and tissue distribution of atrazine and its main metabolites in rodent dams, fetuses, and neonates with physiologically based pharmacokinetic modeling

    Energy Technology Data Exchange (ETDEWEB)

    Lin, Zhoumeng [Department of Physiology and Pharmacology, College of Veterinary Medicine, University of Georgia, Athens, GA 30602 (United States); Interdisciplinary Toxicology Program, University of Georgia, Athens, GA 30602 (United States); Fisher, Jeffrey W. [Division of Biochemical Toxicology, National Center for Toxicological Research, Food and Drug Administration, Jefferson, AR 72079 (United States); Wang, Ran [Center for Environmental Health Sciences, Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS 39762 (United States); Institute of Food Safety, Jiangsu Academy of Agricultural Sciences, Nanjing 210014 (China); Ross, Matthew K. [Center for Environmental Health Sciences, Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS 39762 (United States); Filipov, Nikolay M., E-mail: filipov@uga.edu [Department of Physiology and Pharmacology, College of Veterinary Medicine, University of Georgia, Athens, GA 30602 (United States); Interdisciplinary Toxicology Program, University of Georgia, Athens, GA 30602 (United States)

    2013-11-15

    Atrazine (ATR) is a widely used chlorotriazine herbicide, a ubiquitous environmental contaminant, and a potential developmental toxicant. To quantitatively evaluate placental/lactational transfer and fetal/neonatal tissue dosimetry of ATR and its major metabolites, physiologically based pharmacokinetic models were developed for rat dams, fetuses and neonates. These models were calibrated using pharmacokinetic data from rat dams repeatedly exposed (oral gavage; 5 mg/kg) to ATR followed by model evaluation against other available rat data. Model simulations corresponded well to the majority of available experimental data and suggest that: (1) the fetus is exposed to both ATR and its major metabolite didealkylatrazine (DACT) at levels similar to maternal plasma levels, (2) the neonate is exposed mostly to DACT at levels two-thirds lower than maternal plasma or fetal levels, while lactational exposure to ATR is minimal, and (3) gestational carryover of DACT greatly affects its neonatal dosimetry up until mid-lactation. To test the model's cross-species extrapolation capability, a pharmacokinetic study was conducted with pregnant C57BL/6 mice exposed (oral gavage; 5 mg/kg) to ATR from gestational day 12 to 18. By using mouse-specific parameters, the model predictions fitted well with the measured data, including placental ATR/DACT levels. However, fetal concentrations of DACT were overestimated by the model (10-fold). This overestimation suggests that only around 10% of the DACT that reaches the fetus is tissue-bound. These rodent models could be used in fetal/neonatal tissue dosimetry predictions to help design/interpret early life toxicity/pharmacokinetic studies with ATR and as a foundation for scaling to humans. - Highlights: • We developed PBPK models for atrazine in rat dams, fetuses, and neonates. • We conducted pharmacokinetic (PK) study with atrazine in pregnant mice. • Model predictions were in good agreement with experimental rat and mouse PK data

  9. Estimation of placental and lactational transfer and tissue distribution of atrazine and its main metabolites in rodent dams, fetuses, and neonates with physiologically based pharmacokinetic modeling

    International Nuclear Information System (INIS)

    Lin, Zhoumeng; Fisher, Jeffrey W.; Wang, Ran; Ross, Matthew K.; Filipov, Nikolay M.

    2013-01-01

    Atrazine (ATR) is a widely used chlorotriazine herbicide, a ubiquitous environmental contaminant, and a potential developmental toxicant. To quantitatively evaluate placental/lactational transfer and fetal/neonatal tissue dosimetry of ATR and its major metabolites, physiologically based pharmacokinetic models were developed for rat dams, fetuses and neonates. These models were calibrated using pharmacokinetic data from rat dams repeatedly exposed (oral gavage; 5 mg/kg) to ATR followed by model evaluation against other available rat data. Model simulations corresponded well to the majority of available experimental data and suggest that: (1) the fetus is exposed to both ATR and its major metabolite didealkylatrazine (DACT) at levels similar to maternal plasma levels, (2) the neonate is exposed mostly to DACT at levels two-thirds lower than maternal plasma or fetal levels, while lactational exposure to ATR is minimal, and (3) gestational carryover of DACT greatly affects its neonatal dosimetry up until mid-lactation. To test the model's cross-species extrapolation capability, a pharmacokinetic study was conducted with pregnant C57BL/6 mice exposed (oral gavage; 5 mg/kg) to ATR from gestational day 12 to 18. By using mouse-specific parameters, the model predictions fitted well with the measured data, including placental ATR/DACT levels. However, fetal concentrations of DACT were overestimated by the model (10-fold). This overestimation suggests that only around 10% of the DACT that reaches the fetus is tissue-bound. These rodent models could be used in fetal/neonatal tissue dosimetry predictions to help design/interpret early life toxicity/pharmacokinetic studies with ATR and as a foundation for scaling to humans. - Highlights: • We developed PBPK models for atrazine in rat dams, fetuses, and neonates. • We conducted pharmacokinetic (PK) study with atrazine in pregnant mice. • Model predictions were in good agreement with experimental rat and mouse PK data.

  10. Modeling Incoherent Electron Cloud Effects

    International Nuclear Information System (INIS)

    Vay, Jean-Luc; Benedetto, E.; Fischer, W.; Franchetti, G.; Ohmi, K.; Schulte, D.; Sonnad, K.; Tomas, R.; Vay, J.-L.; Zimmermann, F.; Rumolo, G.; Pivi, M.; Raubenheimer, T.

    2007-01-01

    Incoherent electron effects could seriously limit the beam lifetime in proton or ion storage rings, such as LHC, SPS, or RHIC, or blow up the vertical emittance of positron beams, e.g., at the B factories or in linear-collider damping rings. Different approaches to modeling these effects each have their own merits and drawbacks. We describe several simulation codes which simplify the descriptions of the beam-electron interaction and of the accelerator structure in various different ways, and present results for a toy model of the SPS. In addition, we present evidence that for positron beams the interplay of incoherent electron-cloud effects and synchrotron radiation can lead to a significant increase in vertical equilibrium emittance. The magnitude of a few incoherent e+e- scattering processes is also estimated. Options for future code development are reviewed

  11. Are Quantum Models for Order Effects Quantum?

    Science.gov (United States)

    Moreira, Catarina; Wichert, Andreas

    2017-12-01

    The application of principles of Quantum Mechanics in areas outside of physics has been getting increasing attention in the scientific community in an emergent disciplined called Quantum Cognition. These principles have been applied to explain paradoxical situations that cannot be easily explained through classical theory. In quantum probability, events are characterised by a superposition state, which is represented by a state vector in a N-dimensional vector space. The probability of an event is given by the squared magnitude of the projection of this superposition state into the desired subspace. This geometric approach is very useful to explain paradoxical findings that involve order effects, but do we really need quantum principles for models that only involve projections? This work has two main goals. First, it is still not clear in the literature if a quantum projection model has any advantage towards a classical projection. We compared both models and concluded that the Quantum Projection model achieves the same results as its classical counterpart, because the quantum interference effects play no role in the computation of the probabilities. Second, it intends to propose an alternative relativistic interpretation for rotation parameters that are involved in both classical and quantum models. In the end, instead of interpreting these parameters as a similarity measure between questions, we propose that they emerge due to the lack of knowledge concerned with a personal basis state and also due to uncertainties towards the state of world and towards the context of the questions.

  12. Main extracts and hypolipidemic effects of the Bauhinia racemosa Lam. leaf extract in HFD-fed hamsters.

    Science.gov (United States)

    Sashidhara, Koneni V; Singh, Suriya P; Srivastava, Anuj; Puri, Anju

    2013-01-01

    The lipid lowering effects of ethanolic extract (BR) obtained from leaves of Bauhinia racemosa on hyperlipidemic hamsters were examined. BR showed significant lowering of lipid profile at a dose of 250 mg kg(-1) body-wt of hamster. Chloroform fraction (F2) obtained from BR showed pronounced activity at lower dose of 100 mg kg(-1). F2 gave two most active fractions (L and T) whose chromatographic separations led to the isolation of constituents 1-5, which are being reported for the first time from this natural source. The results of activity profile of the plant were found to be better than the standard drug lovastatin.

  13. Photoaggregation of crystallins (main proteins of eye lens) under the effect of XeCl laser radiation

    Science.gov (United States)

    Soustov, Lev V.; Chelnokov, Evgeny V.; Bityurin, Nikita M.; Kiselev, A. L.; Nemov, V. V.; Sergeev, Yu. V.; Ostrovsky, Michail A.

    2004-07-01

    UV light is one of primary factors associated with cataract formation in the eye lens. α-, β-, γ-Crystallins maintain lens transparency, and damage to these proteins plays a major role in cataract formation. The effect of XeCl laser radiation (308 nm) on βL-crystallin solution is studied. The strong dependence of protein aggregation kinetics on both laser fluence (w) and repetition rate (F) is investigated. The kinetics features are similar to those of carbonic anhydrase photoaggregation studied previously.

  14. Modeling the Effect of Oil Price on Global Fertilizer Prices

    NARCIS (Netherlands)

    P-Y. Chen (Ping-Yu); C-L. Chang (Chia-Lin); C-C. Chen (Chi-Chung); M.J. McAleer (Michael)

    2010-01-01

    textabstractThe main purpose of this paper is to evaluate the effect of crude oil price on global fertilizer prices in both the mean and volatility. The endogenous structural breakpoint unit root test, the autoregressive distributed lag (ARDL) model, and alternative volatility models, including the

  15. Diallel analysis of corn for special use as corn grits: determining the main genetic effects for corn gritting ability.

    Science.gov (United States)

    Conrado, T V; Scapim, C A; Bignotto, L S; Pinto, R J B; Freitas, I L J; Amaral, A T; Pinheiro, A C

    2014-08-26

    Corn grits are used for various purposes such as flakes, snacks, livestock feed, hominy, extruded products, beer, etc. The grit size proportion varies according to the hybrid, and thus, once the use of the grits is linked to the particle size, determining the genetic effects is essential to develop hybrids for any specific use. For this purpose a complete diallel series of crosses, involving eight parents, was performed near Maringá, PR, Brazil. The objective of this study was to evaluate the general (GCA) and specific (SCA) combining abilities of 28 progeny for selection of hybrids for breeding programs and extraction of inbred lines for hybrid development. The response variables, such as plant height, ear insertion height, crop stand, grain yield, and grits, small grits and bran production, were gauged and appraised for each of the 28 progeny. The trait effects and GCA were significant for all response variables, while for SCA, only grain yield and crop stand showed significance (P < 0.05), according to Griffing (1955) analysis. A significant weak negative partial correlation was found between grain yield and grits conversion. In relation to the hybrid selection for breeding programs, the parent IAC Nelore was highly recommended for recurrent selection and the hybrids IPR 119 x HT 392 and IAC Nelore x HD 332 for the extraction of pure lines for hybrid development.

  16. Phenological models to predict the main flowering phases of olive ( Olea europaea L.) along a latitudinal and longitudinal gradient across the Mediterranean region

    Science.gov (United States)

    Aguilera, Fátima; Fornaciari, Marco; Ruiz-Valenzuela, Luis; Galán, Carmen; Msallem, Monji; Dhiab, Ali Ben; la Guardia, Consuelo Díaz-de; del Mar Trigo, María; Bonofiglio, Tommaso; Orlandi, Fabio

    2015-05-01

    The aim of the present study was to develop pheno-meteorological models to explain and forecast the main olive flowering phenological phases within the Mediterranean basin, across a latitudinal and longitudinal gradient that includes Tunisia, Spain, and Italy. To analyze the aerobiological sampling points, study periods from 13 years (1999-2011) to 19 years (1993-2011) were used. The forecasting models were constructed using partial least-squares regression, considering both the flowering start and full-flowering dates as dependent variables. The percentages of variance explained by the full-flowering models (mean 84 %) were greater than those explained by the flowering start models (mean 77 %). Moreover, given the time lag from the North African areas to the central Mediterranean areas in the main olive flowering dates, the regional full-flowering predictive models are proposed as the most useful to improve the knowledge of the influence of climate on the olive tree floral phenology. The meteorological parameters related to the previous autumn and both the winter and the spring seasons, and above all the temperatures, regulate the reproductive phenology of olive trees in the Mediterranean area. The mean anticipation of flowering start and full flowering for the future period from 2081 to 2100 was estimated at 10 and 12 days, respectively. One question can be raised: Will the olive trees located in the warmest areas be northward displaced or will they be able to adapt their physiology in response to the higher temperatures? The present study can be considered as an approach to design more detailed future bioclimate research.

  17. Evolution models of helium white dwarf--main-sequence star merger remnants: the mass distribution of single low-mass white dwarfs

    OpenAIRE

    Zhang, Xianfei; Hall, Philip D.; Jeffery, C. Simon; Bi, Shaolan

    2017-01-01

    It is not known how single white dwarfs with masses less than 0.5Msolar -- low-mass white dwarfs -- are formed. One way in which such a white dwarf might be formed is after the merger of a helium-core white dwarf with a main-sequence star that produces a red giant branch star and fails to ignite helium. We use a stellar-evolution code to compute models of the remnants of these mergers and find a relation between the pre-merger masses and the final white dwarf mass. Combining our results with ...

  18. Space Shuttle Main Engine Low Pressure Oxidizer Turbo-Pump Inducer Dynamic Environment Characterization through Water Model and Hot-Fire Testing

    Science.gov (United States)

    Arellano, Patrick; Patton, Marc; Schwartz, Alan; Stanton, David

    2006-01-01

    The Low Pressure Oxidizer Turbopump (LPOTP) inducer on the Block II configuration Space Shuttle Main Engine (SSME) experienced blade leading edge ripples during hot firing. This undesirable condition led to a minor redesign of the inducer blades. This resulted in the need to evaluate the performance and the dynamic environment of the redesign, relative to the current configuration, as part of the design acceptance process. Sub-scale water model tests of the two inducer configurations were performed, with emphasis on the dynamic environment due to cavitation induced vibrations. Water model tests were performed over a wide range of inlet flow coefficient and pressure conditions, representative of the scaled operating envelope of the Block II SSME, both in flight and in ground hot-fire tests, including all power levels. The water test hardware, facility set-up, type and placement of instrumentation, the scope of the test program, specific test objectives, data evaluation process and water test results that characterize and compare the two SSME LPOTP inducers are discussed. In addition, dynamic characteristics of the two water models were compared to hot fire data from specially instrumented ground tests. In general, good agreement between the water model and hot fire data was found, which confirms the value of water model testing for dynamic characterization of rocket engine turbomachinery.

  19. Artificial Aging Effects on Cryogenic Fracture Toughness of the Main Structural Alloy for the Super Lightweight Tank

    Science.gov (United States)

    Chen, P. S.; Stanton, W. P.

    2002-01-01

    In 1996, Marshall Space Flight Center developed a multistep heating rate-controlled (MSRC) aging technique that significantly enhanced cryogenic fracture toughness (CFT) and reduced the statistical spread of fracture toughness values in alloy 2195 by controlling the location and size of strengthening precipitate T1. However, it could not be readily applied to flight-related hardware production, primarily because large-scale production furnaces are unable to maintain a heating rate of 0.6 C (1 F)/hr. In August 1996, a new program was initiated to determine whether the MSRC aging treatment could be further modified to facilitate its implementation to flight hardware production. It was successfully redesigned into a simplified two-step aging treatment consisting of 132 C (270 F)/20 hr + 138 C (280 F)/40 hr. Results indicated that two-step aging can achieve the same yield strength levels as those produced by conventional aging while providing greatly improved ductility. Two-step aging proved to be very effective at enhancing CFT, enabling previously rejected materials to meet simulated service requirements. Cryogenic properties are improved by controlling T1 nucleation and growth so that they are promoted in the matrix and suppressed in the subgrain boundaries.

  20. Effects of stored feed cropping systems and farm size on the profitability of Maine organic dairy farm simulations.

    Science.gov (United States)

    Hoshide, A K; Halloran, J M; Kersbergen, R J; Griffin, T S; DeFauw, S L; LaGasse, B J; Jain, S

    2011-11-01

    United States organic dairy production has increased to meet the growing demand for organic milk. Despite higher prices received for milk, organic dairy farmers have come under increasing financial stress due to increases in concentrated feed prices over the past few years, which can make up one-third of variable costs. Market demand for milk has also leveled in the last year, resulting in some downward pressure on prices paid to dairy farmers. Organic dairy farmers in the Northeast United States have experimented with growing different forage and grain crops to maximize on-farm production of protein and energy to improve profitability. Three representative organic feed systems were simulated using the integrated farm system model for farms with 30, 120, and 220 milk cows. Increasing intensity of equipment use was represented by organic dairy farms growing only perennial sod (low) to those with corn-based forage systems, which purchase supplemental grain (medium) or which produce and feed soybeans (high). The relative profitability of these 3 organic feed systems was strongly dependent on dairy farm size. From results, we suggest smaller organic dairy farms can be more profitable with perennial sod-based rather than corn-based forage systems due to lower fixed costs from using only equipment associated with perennial forage harvest and storage. The largest farm size was more profitable using a corn-based system due to greater economies of scale for growing soybeans, corn grain, winter cereals, and corn silages. At an intermediate farm size of 120 cows, corn-based forage systems were more profitable if perennial sod was not harvested at optimum quality, corn was grown on better soils, or if milk yield was 10% higher. Delayed harvest decreased the protein and energy content of perennial sod crops, requiring more purchased grain to balance the ration and resulting in lower profits. Corn-based systems were less affected by lower perennial forage quality, as corn silage

  1. Species Composition of Sand Flies (Diptera: Psychodidae) and Modeling the Spatial Distribution of Main Vectors of Cutaneous Leishmaniasis in Hormozgan Province, Southern Iran.

    Science.gov (United States)

    Hanafi-Bojd, Ahmad Ali; Khoobdel, Mehdi; Soleimani-Ahmadi, Moussa; Azizi, Kourosh; Aghaei Afshar, Abbas; Jaberhashemi, Seyed Aghil; Fekri, Sajjad; Safari, Reza

    2018-02-28

    Cutaneous Leishmaniasis (CL) is one of the main neglected vector-borne diseases in the Middle East, including Iran. This study aimed to map the spatial distribution and species composition of sand flies in Hormozgan Province and to predict the best ecological niches for main CL vectors in this area. A database that included all earlier studies on sand flies in Hormozgan Province was established. Sand flies were also collected from some localities across the province. Prediction maps for main vectors were developed using MaxEnt model. A total of 27 sand fly species were reported from the study area. Phlebotomus papatasi Scopoli, Phlebotomus sergenti s.l. Parrot, Phlebotomus alexandri Sinton, Sergentomyia sintoni Pringle, Sergentomyia clydei Sinton, Sergentomyia tiberiadis Adler, and Sergentomyia baghdadis Adler (Diptera: Psychodidae) had the widest distribution range. The probability of their presence as the main vectors of CL was calculated to be 0.0003-0.9410 and 0.0031-0.8880 for P. papatasi and P. sergenti s.l., respectively. The best ecological niches for P. papatasi were found in the central south, southeast, and a narrow area in southwest, whereas central south to northern area had better niches for P. sergenti s.l. The endemic areas are in Bandar-e Jask, where transmission occurs, whereas in Bastak, the cases were imported from endemic foci of Fars province. In conclusion, proven and suspected vectors of CL and VL were recorded in this study. Due to the existence of endemic foci of CL, and favorite ecological niches for its vectors, there is potential risk of emerging CL in new areas.

  2. Trampoline Effect: Observations and Modeling

    Science.gov (United States)

    Guyer, R.; Larmat, C. S.; Ulrich, T. J.

    2009-12-01

    The Iwate-Miyagi earthquake at site IWTH25 (14 June 2008) had large, asymmetric at surface vertical accelerations prompting the sobriquet trampoline effect (Aoi et. al. 2008). In addition the surface acceleration record showed long-short waiting time correlations and vertical-horizontal acceleration correlations. A lumped element model, deduced from the equations of continuum elasticity, is employed to describe the behavior at this site in terms of a surface layer and substrate. Important ingredients in the model are the nonlinear vertical coupling between the surface layer and the substrate and the nonlinear horizontal frictional coupling between the surface layer and the substrate. The model produces results in qualitative accord with observations: acceleration asymmetry, Fourier spectrum, waiting time correlations and vertical acceleration-horizontal acceleration correlations. [We gratefully acknowledge the support of the U. S. Department of Energy through the LANL/LDRD Program for this work].

  3. Comparison of Farm Structures, Success Factors, Obstacles, Clients’ Expectations and Policy Wishes of Urban Farming’s Main Business Models in North Rhine-Westphalia, Germany

    Directory of Open Access Journals (Sweden)

    Bernd Pölling

    2016-05-01

    Full Text Available Low-cost specialization, differentiation, and diversification are common business models of urban farms in developed countries. Similarities and differences between them as well as detailed insights into specific farm characteristics are widely absent in scientific discourses. This paper compares farm structures, success factors, obstacles, clients’ expectations, and policy wishes between specialized, differentiated, and diversified farms as well as diversifiers into agriculture. A standardized questionnaire was used for 21 personal in-depth farm interviews located in metropolitan areas of North Rhine-Westphalia, Germany. Being located in a metropolitan area is the most often named Unique Selling Proposition (USP. This is also mentioned as most important success factor followed by sociability and personal contact to clients, which both underpin the importance of direct producer-consumer linkages in urban settings. Additionally, it is assumed that a single food criterion is not sufficient to be successful, but several have to be merged to meet clients’ expectations. In terms of marketing, differentiated and diversified farmers prefer a multi-channel approach, while specialized farmers and diversifiers into agriculture focus mainly on one specific channel. While both specialized farmers and diversifiers into agriculture cultivate smaller areas of farmland, the latter one offers the greatest number of jobs including those outside agricultural production. The findings obtained are expected to support farms and agricultural advisory services in individual decision making of future business development strategies and increase knowledge of urban farming’s main business models.

  4. Toy models for wrapping effects

    International Nuclear Information System (INIS)

    Penedones, Joao; Vieira, Pedro

    2008-01-01

    The anomalous dimensions of local single trace gauge invariant operators in N = 4 supersymmetric Yang-Mills theory can be computed by diagonalizing a long range integrable Hamiltonian by means of a perturbative asymptotic Bethe ansatz. This formalism breaks down when the number of fields of the composite operator is smaller than the range of the Hamiltonian which coincides with the order in perturbation theory at study. We analyze two spin chain toy models which might shed some light on the physics behind these wrapping effects. One of them, the Hubbard model, is known to be closely related to N = 4 SYM. In this example, we find that the knowledge of the effective spin chain description is insufficient to reconstruct the finite size effects of the underlying electron theory. We compute the wrapping corrections for generic states and relate them to a Luscher like approach. The second toy models are long range integrable Hamiltonians built from the standard algebraic Bethe ansatz formalism. This construction is valid for any symmetry group. In particular, for non-compact groups it exhibits an interesting relation between wrapping interactions and transcendentality.

  5. A systematic review and checklist presenting the main challenges for health economic modeling in personalized medicine: towards implementing patient-level models.

    Science.gov (United States)

    Degeling, Koen; Koffijberg, Hendrik; IJzerman, Maarten J

    2017-02-01

    The ongoing development of genomic medicine and the use of molecular and imaging markers in personalized medicine (PM) has arguably challenged the field of health economic modeling (HEM). This study aims to provide detailed insights into the current status of HEM in PM, in order to identify if and how modeling methods are used to address the challenges described in literature. Areas covered: A review was performed on studies that simulate health economic outcomes for personalized clinical pathways. Decision tree modeling and Markov modeling were the most observed methods. Not all identified challenges were frequently found, challenges regarding companion diagnostics, diagnostic performance, and evidence gaps were most often found. However, the extent to which challenges were addressed varied considerably between studies. Expert commentary: Challenges for HEM in PM are not yet routinely addressed which may indicate that either (1) their impact is less severe than expected, (2) they are hard to address and therefore not managed appropriately, or (3) HEM in PM is still in an early stage. As evidence on the impact of these challenges is still lacking, we believe that more concrete examples are needed to illustrate the identified challenges and to demonstrate methods to handle them.

  6. A systematic review and checklist presenting the main challenges for health economic modeling in personalized medicine : towards implementing patient-level models

    NARCIS (Netherlands)

    Degeling, Koen; Koffijberg, Hendrik; IJzerman, Maarten Joost

    2017-01-01

    Introduction: The ongoing development of genomic medicine and the use of molecular and imaging markers in personalized medicine (PM) has arguably challenged the field of health economic modeling (HEM). This study aims to provide detailed insights into the current status of HEM in PM, in order to

  7. Modeling quantization effects in field effect transistors

    International Nuclear Information System (INIS)

    Troger, C.

    2001-06-01

    Numerical simulation in the field of semiconductor device development advanced to a valuable, cost-effective and flexible facility. The most widely used simulators are based on classical models, as they need to satisfy time and memory constraints. To improve the performance of field effect transistors such as MOSFETs and HEMTs these devices are continuously scaled down in their dimensions. Consequently the characteristics of such devices are getting more and more determined by quantum mechanical effects arising from strong transversal fields in the channel. In this work an approach based on a two-dimensional electron gas is used to describe the confinement of the carriers. Quantization is considered in one direction only. For the derivation of a one-dimensional Schroedinger equation in the effective mass framework a non-parabolic correction for the energy dispersion due to Kane is included. For each subband a non-parabolic dispersion relation characterized by subband masses and subband non-parabolicity coefficients is introduced and the parameters are calculated via perturbation theory. The method described in this work has been implemented in a software tool that performs a self-consistent solution of Schroedinger- and Poisson-equation for a one-dimensional cut through a MOS structure or heterostructure. The calculation of the carrier densities is performed assuming Fermi-Dirac statistics. In the case of a MOS structure a metal or a polysilicon gate is considered and an arbitrary gate bulk voltage can be applied. This allows investigating quantum mechanical effects in capacity calculations, to compare the simulated data with measured CV curves and to evaluate the results obtained with a quantum mechanical correction for the classical electron density. The behavior of the defined subband parameters is compared to the value of the mass and the non-parabolicity coefficient from the model due to Kane. Finally the presented characterization of the subbands is applied

  8. Pre-treatment growth and IGF-I deficiency as main predictors of response to growth hormone therapy in neural models

    Directory of Open Access Journals (Sweden)

    Urszula Smyczyn´ska

    2018-01-01

    Full Text Available Mathematical models have been applied in prediction of growth hormone treatment effectiveness in children since the end of 1990s. Usually they were multiple linear regression models; however, there are also examples derived by empirical non-linear methods. Proposed solution consists in application of machine learning technique – artificial neural networks – to analyse this problem. This new methodology, contrary to previous ones, allows detection of both linear and non-linear dependencies without assuming their character a priori. The aims of this work included: development of models predicting separately growth during 1st year of treatment and final height as well as identification of important predictors and in-depth analysis of their influence on treatment’s effectiveness. The models were derived on the basis of clinical data of 272 patients treated for at least 1 year, 133 of whom have already attained final height. Starting from models containing 17 and 20 potential predictors, respectively for 1st year and final height model, we were able to reduce their number to 9 and 10. Basing on the final models, IGF-I concentration and earlier growth were indicated as belonging to most important predictors of response to GH therapy, while results of GH secretion tests were automatically excluded as insignificant. Moreover, majority of the dependencies were observed to be non-linear, thus using neural networks seems to be reasonable approach despite it being more complex than previously applied methods.

  9. Shaking table test of a base isolated model in main control room of nuclear power plant using LRB (lead rubber bearing)

    International Nuclear Information System (INIS)

    Ham, K. W.; Lee, K. J.; Suh, Y. P.

    2005-01-01

    LRB(Lead Rubber Bearing) is a widely used isolation system which is installed between equipment and foundation to reduce seismic vibration from ground. LRB is consist of bearings which are resistant to lateral motion and torsion and has a high vertical stiffness. For that reason, several studies are conducted to apply LRB to the nuclear power plant. In this study, we designed two types of main control floor systems (type I, type II) and a number of shaking table tests with and without isolation system were conducted to evaluate floor isolation effectiveness of LRB

  10. Better models are more effectively connected models

    Science.gov (United States)

    Nunes, João Pedro; Bielders, Charles; Darboux, Frederic; Fiener, Peter; Finger, David; Turnbull-Lloyd, Laura; Wainwright, John

    2016-04-01

    The concept of hydrologic and geomorphologic connectivity describes the processes and pathways which link sources (e.g. rainfall, snow and ice melt, springs, eroded areas and barren lands) to accumulation areas (e.g. foot slopes, streams, aquifers, reservoirs), and the spatial variations thereof. There are many examples of hydrological and sediment connectivity on a watershed scale; in consequence, a process-based understanding of connectivity is crucial to help managers understand their systems and adopt adequate measures for flood prevention, pollution mitigation and soil protection, among others. Modelling is often used as a tool to understand and predict fluxes within a catchment by complementing observations with model results. Catchment models should therefore be able to reproduce the linkages, and thus the connectivity of water and sediment fluxes within the systems under simulation. In modelling, a high level of spatial and temporal detail is desirable to ensure taking into account a maximum number of components, which then enables connectivity to emerge from the simulated structures and functions. However, computational constraints and, in many cases, lack of data prevent the representation of all relevant processes and spatial/temporal variability in most models. In most cases, therefore, the level of detail selected for modelling is too coarse to represent the system in a way in which connectivity can emerge; a problem which can be circumvented by representing fine-scale structures and processes within coarser scale models using a variety of approaches. This poster focuses on the results of ongoing discussions on modelling connectivity held during several workshops within COST Action Connecteur. It assesses the current state of the art of incorporating the concept of connectivity in hydrological and sediment models, as well as the attitudes of modellers towards this issue. The discussion will focus on the different approaches through which connectivity

  11. Measurement of Hydrologic Streamflow Metrics and Estimation of Streamflow with Lumped Parameter Models in a Managed Lake System, Sebago Lake, Maine

    Science.gov (United States)

    Reeve, A. S.; Martin, D.; Smith, S. M.

    2013-12-01

    Surface waters within the Sebago Lake watershed (southern Maine, USA) provide a variety of economically and intrinsically valuable recreational, commercial and environmental services. Different stakeholder groups for the 118 km2 Sebago Lake and surrounding watershed advocate for different lake and watershed management strategies, focusing on the operation of a dam at the outflow from Sebago Lake. While lake level in Sebago Lake has been monitored for over a century, limited data is available on the hydrologic processes that drive lake level and therefore impact how dam operation (and other changes to the region) will influence the hydroperiod of the lake. To fill this information gap several tasks were undertaken including: 1) deploying data logging pressure transducers to continuously monitor stream stage in nine tributaries, 2) measuring stream discharge at these sites to create rating curves for the nine tributaries, and using the resulting continuous discharge records to 3) calibrate lumped parameter computer models based on the GR4J model, modified to include a degree-day snowmelt routine. These lumped parameter models have been integrated with a simple lake water-balance model to estimate lake level and its response to different scenarios including dam management strategies. To date, about three years of stream stage data have been used to estimate stream discharge in all monitored tributaries (data collection is ongoing). Baseflow separation indices (BFI) for 2010 and 2011 using the USGS software PART and the Eckhart digital filter in WHAT range from 0.80-0.86 in the Crooked River and Richmill Outlet,followed by Northwest (0.75) and Muddy (0.53-0.56) Rivers, with the lowest BFI measured in Sticky River (0.41-0.56). The BFI values indicate most streams have significant groundwater (or other storage) inputs. The lumped parameter watershed model has been calibrated for four streams (Nash-Sutcliffe = 0.4 to 0.9), with the other major tributaries containing

  12. Effects of pilot injection parameters on low temperature combustion diesel engines equipped with solenoid injectors featuring conventional and rate-shaped main injection

    International Nuclear Information System (INIS)

    D’Ambrosio, S.; Ferrari, A.

    2016-01-01

    Highlights: • The influence of the principal pilot injection parameters is discussed for low-temperature combustion systems. • Swirl-sweep and dwell-time sweep results are combined to analyze soot emissions. • The pilot injection effects are investigated in injection profiles featuring rate-shaped main injections. - Abstract: The potential of pilot injection has been assessed on a low-temperature combustion diesel engine for automotive applications, which was characterized by a reduced compression-ratio, high EGR rates and postponed main injection timings. Dwell time sweeps have been carried out for pilot injections with distinct energizing times under different representative steady-state working conditions of the medium load and speed area of the New European Driving Cycle. The results of in-cylinder analyses of the pressure, heat-release rate, temperature and emissions are presented. Combustion noise has been shown to decrease significantly when the pilot injected mass increases, while it is scarcely affected by the dwell time between the pilot and main injections. The HC, CO and fuel consumption trends, with respect to both the pilot injection dwell time and mass, are in line with those of conventional combustion systems, and in particular decreasing trends occur as the pilot injection energizing time is increased. Furthermore, a reduced sensitivity of NO_x emissions to both dwell time and pilot injected mass has been found, compared to conventional combustion systems. Finally, it has been observed that soot emissions diminish as the energizing time is shortened, and their dependence on dwell time is influenced to a great extent by the presence of local zones with reduced air-to-fuel ratios within the cylinder. A combined analysis of the results of swirl sweeps and dwell time sweeps is here proposed as a methodology for the detection of any possible interference between pilot combustion burned gases and the main injected fuel. The effect of pilot

  13. Atomic Models for Motional Stark Effects Diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Gu, M F; Holcomb, C; Jayakuma, J; Allen, S; Pablant, N A; Burrell, K

    2007-07-26

    We present detailed atomic physics models for motional Stark effects (MSE) diagnostic on magnetic fusion devices. Excitation and ionization cross sections of the hydrogen or deuterium beam traveling in a magnetic field in collisions with electrons, ions, and neutral gas are calculated in the first Born approximation. The density matrices and polarization states of individual Stark-Zeeman components of the Balmer {alpha} line are obtained for both beam into plasma and beam into gas models. A detailed comparison of the model calculations and the MSE polarimetry and spectral intensity measurements obtained at the DIII-D tokamak is carried out. Although our beam into gas models provide a qualitative explanation for the larger {pi}/{sigma} intensity ratios and represent significant improvements over the statistical population models, empirical adjustment factors ranging from 1.0-2.0 must still be applied to individual line intensities to bring the calculations into full agreement with the observations. Nevertheless, we demonstrate that beam into gas measurements can be used successfully as calibration procedures for measuring the magnetic pitch angle through {pi}/{sigma} intensity ratios. The analyses of the filter-scan polarization spectra from the DIII-D MSE polarimetry system indicate unknown channel and time dependent light contaminations in the beam into gas measurements. Such contaminations may be the main reason for the failure of beam into gas calibration on MSE polarimetry systems.

  14. Downscaling, 2-way Nesting, and Data Assimilative Modeling in Coastal and Shelf Waters of the U.S. Mid-Atlantic Bight and Gulf of Maine

    Science.gov (United States)

    Wilkin, J.; Levin, J.; Lopez, A.; Arango, H.

    2016-02-01

    Coastal ocean models that downscale output from basin and global scale models are widely used to study regional circulation at enhanced resolution and locally important ecosystem, biogeochemical, and geomorphologic processes. When operated as now-cast or forecast systems, these models offer predictions that assist decision-making for numerous maritime applications. We describe such a system for shelf waters of the Mid-Atlantic Bight (MAB) and Gulf of Maine (GoM) where the MARACOOS and NERACOOS associations of U.S. IOOS operate coastal ocean observing systems that deliver a dense observation set using CODAR HF-radar, autonomous underwater glider vehicles (AUGV), telemetering moorings, and drifting buoys. Other U.S. national and global observing systems deliver further sustained observations from moorings, ships, profiling floats, and a constellation of satellites. Our MAB and GoM re-analysis and forecast system uses the Regional Ocean Modeling System (ROMS; myroms.org) with 4-dimensional Variational (4D-Var) data assimilation to adjust initial conditions, boundary conditions, and surface forcing in each analysis cycle. Data routinely assimilated include CODAR velocities, altimeter satellite sea surface height (with coastal corrections), satellite temperature, in situ CTD data from AUGV and ships (NMFS Ecosystem Monitoring voyages), and all in situ data reported via the WMO GTS network. A climatological data assimilative analysis of hydrographic and long-term mean velocity observations specifies the regional Mean Dynamic Topography that augments altimeter sea level anomaly data and is also used to adjust boundary condition biases that would otherwise be introduced in the process of downscaling from global models. System performance is described with respect to the impact of satellite, CODAR and in situ observations on analysis skill. Results from a 2-way nested modeling system that adds enhanced resolution over the NSF OOI Pioneer Array in the central MAB are also

  15. Racial/ethnic variations in the main and buffering effects of ethnic and nonethnic supports on depressive symptoms among five ethnic immigrant groups in Toronto.

    Science.gov (United States)

    Kim, Il-Ho; Noh, Samuel

    2016-01-01

    This study examined variations in the main and buffering effects of ethnic and nonethnic social support on depressive symptoms associated with discrimination among five immigrant groups in Toronto. Data were taken from the Toronto Study of Settlement and Health, a cross-sectional survey of adult immigrants from five ethnic communities (Vietnamese, Ethiopian, Iranian, Korean, and Irish) in Toronto. A total of 900 surveys were collected through face-to-face interviews conducted between April and September 2001. Significant ethnic variations were observed in the effects of both ethnic and nonethnic social supports on discrimination-related depressive symptoms. Regarding the main effect, ethnic social support was significantly stronger for Iranian, Ethiopian, and Korean immigrants than for Irish immigrants. The benefits of nonethnic support were stronger for Iranian immigrants compared to the effect found in the Irish sample. With respect to stress-buffering or stress-moderating effects of social support, ethnic support was significant in all ethnic groups, except the Vietnamese group. Nonethnic support aggravated the negative impact of discrimination on depressive symptoms in the Irish group, but exerted a stress-buffering effect in the Iranian group. Overall, social supports received from fellow ethnic group members had significant main effects (suppressing depressive symptoms) and stress-buffering effects and were most pronounced in the minority ethnic immigrant groups of Ethiopians, Koreans, and Iranians. The effects were least evident among the Vietnamese and Irish. Evidence for the stress-suppressing and stress-buffering role of cross-ethnic group supports was unclear, and even inverted among Irish immigrants. Empirical evidence from the current study seems to support the sociocultural similarity hypothesis of social support.

  16. Main Memory DBMS

    NARCIS (Netherlands)

    P.A. Boncz (Peter); L. Liu (Lei); M. Tamer Özsu

    2008-01-01

    htmlabstractA main memory database system is a DBMS that primarily relies on main memory for computer data storage. In contrast, normal database management systems employ hard disk based persisntent storage.

  17. Adjust of the residuals of the Arima model by means of the analysis of the residuals of the explanatory variables by means of the analysis of main components

    International Nuclear Information System (INIS)

    Bernal Suarez, Nestor Ricardo; Montealegre Bocanegra, Jose Edgar

    2000-01-01

    Based on the previous knowledge and understanding of the causality relationships between the fields of surface temperature of the Pacific and North and South tropical Atlantic oceans and rainfall behaviour in Colombia, we purport to model those relations with a (statistical) transfer model. This work is aimed at improving the adjustment of the model for the monthly mean rainfall registered in Funza (nearby the Capital Bogota). The residues of ARIMA models with six explanatory variables may contribute some percentage to the explanation of the total variability of rainfall as a consequence of their interrelationship. Such effect can be represented as a summary of the six variables, which can be achieved with principal components, taking into account that they are not mutually dependent, since they are white noise time series

  18. A Simulation-Based Linear Fractional Programming Model for Adaptable Water Allocation Planning in the Main Stream of The Songhua River Basin, China

    Directory of Open Access Journals (Sweden)

    Qiang Fu

    2018-05-01

    Full Text Available The potential influence of natural variations in a climate system on global warming can change the hydrological cycle and threaten current strategies of water management. A simulation-based linear fractional programming (SLFP model, which integrates a runoff simulation model (RSM into a linear fractional programming (LFP framework, is developed for optimal water resource planning. The SLFP model has multiple objectives such as benefit maximization and water supply minimization, balancing water conflicts among various water demand sectors, and addressing complexities of water resource allocation system. Lingo and Excel programming solutions were used to solve the model. Water resources in the main stream basin of the Songhua River are allocated for 4 water demand sectors in 8 regions during two planning periods under different scenarios. Results show that the increase or decrease of water supply to the domestic sector is related to the change in population density at different regions in different target years. In 2030, the water allocation in the industrial sector decreased by 1.03–3.52% compared with that in 2020, while the water allocation in the environmental sector increased by 0.12–1.29%. Agricultural water supply accounts for 54.79–77.68% of total water supply in different regions. These changes in water resource allocation for various sectors were affected by different scenarios in 2020; however, water resource allocation for each sector was relatively stable under different scenarios in 2030. These results suggest that the developed SLFP model can help to improve the adjustment of water use structure and water utilization efficiency.

  19. Principales modelos de liderazgo: su significación en el ámbito universitario Main leadership models: its importance in university field

    Directory of Open Access Journals (Sweden)

    Martha Lorena Figueroa Soledispa

    2012-12-01

    Full Text Available El artículo tiene entre sus propósitos valorar los modelos y teorías que han tenido una influencia determinante en el proceso de superación en liderazgo docente, y cómo ello influye en la labor que desarrollan los docentes universitarios para el logro de un rol transformador en su actividad. A través de la historia en este campo son muchos los modelos que han surgido, que han sido utilizados y puestos de moda en algunos momentos por diversas razones. Ante la variedad de los mismos vienen preguntas ineludibles acerca de cuál es el modelo más adecuado o más utilizado cuando de liderazgo docente se trata.The main purpose of this article is to briefly assess the models and theories that have had a determining influence on the bettering process in teaching leadership, and the way it influences the job developed by university teaching personnel, specifically designed to achieve a transformer role of their activity. Through history, there have been many models that have come up, have been used, and have come back into fashion in different moments and for several reasons in this field. In view of their variety, unavoidable questions have come up, about the most suitable or used model when dealing with teaching leadership.

  20. Agronomic effect of empty fruit bunches compost, anorganic fertilizer and endophytic microbes in oil palm main nursery used Ganoderma endemic soil

    Science.gov (United States)

    Hanum, H.; Lisnawita; Tantawi, A. R.

    2018-02-01

    Using of Ganoderma endemic soil in oil palm main nursery is not recomended because produce bad quality seedling. The application of organic and anorganic fertilizer and endophytic microbes are the alternative for solving the problem. The objective of this research is to evaluate the effect of empty fruit bunches compost, anorganic fertilizer and endophytic microbes on growth of oil palm seedling in main nursery. This research used factorial randomized block design. The first factor was combination of empty fruit bunches compost and anorganic fertilizer, The second factor was endophytic microbes consisting of Trichoderma and Aspergillus. The results showed that interaction effect of the both treatment factor used increased growth of seedling in third and fourth month after application. The best growth of seedling was on the treatment of empty fruit bunches compost combined with anorganic fertilizer 150% recommended dosage and Trichoderma viride.

  1. Experimental soil warming effects on CO2 and CH4 flux from a low elevation spruce-fir forest soil in Maine, USA

    Science.gov (United States)

    Lindsey E. Rustad; Ivan J. Fernandez

    1998-01-01

    The effect of soil warming on CO2 and CH4 flux from a spruce-fir forest soil was evaluated at the Howland Integrated Forest Study site in Maine, USA from 1993 to 1995. Elevated soil temperatures (~5 °C) were maintained during the snow-free season (May-November) in replicated 15 × 15-m plots using electric cables buried 1-2...

  2. 3-D thermal analysis using finite difference technique with finite element model for improved design of components of rocket engine turbomachines for Space Shuttle Main Engine SSME

    Science.gov (United States)

    Sohn, Kiho D.; Ip, Shek-Se P.

    1988-01-01

    Three-dimensional finite element models were generated and transferred into three-dimensional finite difference models to perform transient thermal analyses for the SSME high pressure fuel turbopump's first stage nozzles and rotor blades. STANCOOL was chosen to calculate the heat transfer characteristics (HTCs) around the airfoils, and endwall effects were included at the intersections of the airfoils and platforms for the steady-state boundary conditions. Free and forced convection due to rotation effects were also considered in hollow cores. Transient HTCs were calculated by taking ratios of the steady-state values based on the flow rates and fluid properties calculated at each time slice. Results are presented for both transient plots and three-dimensional color contour isotherm plots; they were also converted into universal files to be used for FEM stress analyses.

  3. THE EFFECT OF DIFFERENT OPTIONS OF BLADES MAIN ROTOR ON THE X-SHAPED TAIL ROTOR OF THE MI-171 LL

    Directory of Open Access Journals (Sweden)

    Valery A. Ivchin

    2018-01-01

    Full Text Available This paper describes the effect of different rotor blades on the X-shaped tail rotor of the Mi-171 LL, observed conducting flight tests. The tests were carried out on the same helicopter in the similar atmospheric conditions.The objective of the tests was the comparison of flight performance of two sets of rotor blades of the helicopter Mi-171 LL. However, materials test revealed a difference in the angles of the tail rotor at different MRs with the same takeoff weight.The authors are grateful to I.G. Peskov, S.R. Zamula and A.I. Orlov for assistance in carrying out this work and the preparation of this article.Noted that the helicopter takeoff weight when hovering out of ground effect in ISA with blades from polymer composite materials (PCM exceeds the takeoff weight of the helicopter with the serial blades in the nominal mode of the engine operation at ~ 750kg, in the takeoff mode at ~ 700kg.Knowing the altitude and climatic characteristics of the engine, the obtained dependence allows to determine the balancing value of jрв on hovering at different combinations of pressure altitude and outside air temperature for a given speed of the main rotor (MR.It follows from the work that when the same value Nпр(95/nнвпр3 or Nfact the balancing values of jрв for the helicopter with the main rotor blades from the PCM is less than for the helicopters with serial blades by 0.5…0.9°. The difference in the angles of the tail rotor increases with growing of Nепр(95/nнвпр3 (Nfact. Perhaps this is caused by different induction effect of the main rotor on the tail rotor to the MR from PCM and the serial ones.As follows from the materials, the thrust of the main rotor with blades from PCM with the same engine power is more in comparison with the serial blades. Consequently inductive speeds of the main rotor are more and the angles of the tail rotor are less. It can be assumed that a large induced velocity of the main rotor increases the thrust

  4. The applicability of CFD to simulate and study the mixing process and the thermo-hydraulic consequences of a main steam line break in PWR model

    Directory of Open Access Journals (Sweden)

    Farkas Istvan

    2017-01-01

    Full Text Available This paper focuses on the validation and applicability of CFD to simulate and analyze the thermo-hydraulic consequences of a main steam line break. Extensive validation data come from experiments performed using the Rossendorf coolant mixing model facility. For the calculation, the range of 9 to 12 million hexahe¬dral cells was constructed to capture all details in the interrogation domain in the system. The analysis was performed by running a time-dependent calculation, Detailed analyses were made at different cross-sections in the system to evaluate not only the value of the maximum and minimum temperature, but also the loca¬tion and the time at which it occurs during the transient which is considered to be indicator for the quality of mixing in the system. CFD and experimental results were qualitatively compared; mixing in the cold legs with emergency core cooling systems was overestimated. This could be explained by the sensitivity to the bound¬ary conditions. In the downcomer, the experiments displayed higher mixing: by our assumption this related to the dense measurement grid (they were not modelled. The temperature distribution in the core inlet plane agreed with the measurement results. Minor deviations were seen in the quantitative comparisons: the maximum temperature difference was 2ºC.

  5. Propuesta de un modelo de gestión de mantenimiento y sus principales herramientas de apoyo Proposal of a maintenance management model and its main support tools

    Directory of Open Access Journals (Sweden)

    Pablo Viveros

    2013-04-01

    Full Text Available Este artículo presenta un modelo para la gestión integral del mantenimiento, teniendo en consideración la característica de mejora continua en el tiempo. A modo de introducción y contextualización, se explica la importancia que tiene la alineación de objetivos a todo nivel organizacional para lograr la integración y correcta gestión de la unidad de mantenimiento. El modelo a presentar se compone de siete principales etapas, las cuales deben desarrollarse progresivamente según el escenario actual de la organización, haciendo énfasis en la gestión y optimización sostenida en el tiempo de procesos asociados a la planificación, programación y ejecución del mantenimiento. Adicionalmente, el modelo presentado complementa herramientas de apoyo para el desarrollo e implementación de las etapas, y características operacionales reales, las cuales podrían afectar el desempeño de la unidad de mantenimiento. Finalmente, se presentan algunas consideraciones generales y respectivas conclusiones.This paper presents a model for the integrated management of maintenance, taking into account features of continuous improvement over time. As an introduction and contextualization, it explains the importance of aligning organizational goals at all levels in order to achieve proper integration and management of the maintenance unit. The present model consists of seven main stages, which must be progressively implemented depending on the current scenario of the organization, focusing on management and sustained over time optimization of processes related to planning, programming and maintenance execution. Additionally, the model presented is supported by tools to develop and implement the stages, and provides a real operational context of the industrial maintenance management; which may affect performance. Finally, we present some general considerations and conclusions.

  6. Modeling of the Yarkovsky and YORP effects

    Science.gov (United States)

    Rozitis, B.

    2014-07-01

    The Yarkovsky and YORP effects are now widely regarded to be fundamental mechanisms, in addition to collisions and gravitational forces, which drive the dynamical and physical evolution of small asteroids in the Solar System [1]. They are caused by the net force and torque resulting from the asymmetric reflection and thermal re-radiation of sunlight from an asteroid's surface. The net force (Yarkovsky effect) causes the asteroid's orbit to drift outwards or inwards depending on whether the asteroid is a prograde or retrograde rotator. The first direct measurement of Yarkovsky orbital drift was achieved by sensitive radar-ranging on the near-Earth asteroid (NEA) (6489) Golevka in 2003 [2]. The net torque (YORP effect) changes the asteroid's rotation rate and the direction of its spin axis. It can cause an asteroid to spin faster or slower depending on the shape asymmetry, and the first direct measurement of the YORP rotational acceleration was achieved by lightcurve observations on NEA (54509) YORP in 2007 [3]. Since these first direct detections, the Yarkovsky orbital drift has been detected in several tens of NEAs [4,5], and the YORP rotational acceleration has been detected in four more NEAs [6--9]. Indirect evidence of the action of these two effects has also been seen in the populations of NEAs [10], small main-belt asteroids [11], and asteroid families [12]. Modeling of these effects allows further insights into the properties of detected asteroids to be gained, such as the bulk density, obliquity, and surface thermal properties. Recently, high-precision astrometric observations of the Yarkovsky orbital drift of PHA (101955) Bennu were combined with suitable models informed by thermal-infrared observations to derive a bulk density with an uncertainty comparable to that of in-situ spacecraft investigations [13]. Also, the recent YORP effect detection in (25143) Itokawa was combined with a model utilizing the highly detailed Hayabusa-derived shape model to infer

  7. Modeling the Constructs Contributing to the Effectiveness of Marketing Lecturers

    Science.gov (United States)

    Sweeney, Arthur D. P.; Morrison, Mark D.; Jarratt, Denise; Heffernan, Troy

    2009-01-01

    Student evaluation of teaching has been examined in higher education research for over 70 years but there are gaps in our knowledge about the contribution, and relationships between, the relevant constructs. Recent literature encourages researchers to test multivariate models of Teaching Effectiveness. Seven main constructs known to influence…

  8. Effects of Increasing Doses of UV-B on Main Phenolic Acids Content, Antioxidant Activity and Estimated Biomass in Lavandin (Lavandula x intermedia).

    Science.gov (United States)

    Usano-Alemany, Jaime; Panjai, Lachinee

    2015-07-01

    Lavandin is a well-known aromatic plant cultivated mainly for its valuable essential oil. Nonetheless, little attention has been paid so far to the quantification of other natural products such as polyphenols. Accordingly, we examined the effect of increasing doses of UV-B radiation on the main phenolic content, antioxidant activity and estimated biomass of one year old lavandin pots compared with pots grown outdoors. Significantly higher total phenolic content and concentration of main polyphenols have been found in outdoor plants. Rosmarinic acid has been described as the major phenolic compound in methanolic extracts (max. 25.9 ± 9.7 mg/g(-1) DW). Furthermore, we found that increasing doses of UV-B promote the plant growth of this species as well as the accumulation of phenolic compounds although with less antioxidant capacity in scavenging DPPH radicals. On the other hand, our results showed a remarkable variability among individual plants regarding the content of major phenolic acids. The application of UV-B doses during plant growth could be a method to promote biomass in this species along with the promotion of higher content of valuable secondary metabolites.

  9. Effect of SPL (Spent Pot Liner) and its main components on root growth, mitotic activity and phosphorylation of Histone H3 in Lactuca sativa L.

    Science.gov (United States)

    Freitas, Aline Silva; Fontes Cunha, Isabela Martinez; Andrade-Vieira, Larissa Fonseca; Techio, Vânia Helena

    2016-02-01

    Spent Pot Liner (SPL) is a solid waste from the aluminum industry frequently disposed of in industrial landfills; it can be leached and contaminate the soil, sources of drinking water and plantations, and thus may pose a risk to human health and to ecosystems. Its composition is high variable, including cyanide, fluoride and aluminum salts, which are highly toxic and environmental pollutants. This study evaluated the effect of SPL and its main components on root growth and the mitosis of Lactuca sativa, by investigating the mechanisms of cellular and chromosomal alterations with the aid of immunolocalization. To this end, newly emerged roots of L. sativa were exposed to SPL and its main components (solutions of cyanide, fluoride and aluminum) and to calcium chloride (control) for 48h. After this, root length was measured and cell cycle was examined by means of conventional cytogenetics and immunolocalization. Root growth was inhibited in the treatments with SPL and aluminum; chromosomal and nuclear alterations were observed in all treatments. The immunolocalization evidenced normal dividing cells with regular temporal and spatial distribution of histone H3 phosphorylation at serine 10 (H3S10ph). However, SPL and its main components inhibited the phosphorylation of histone H3 at serine 10, inactivated pericentromeric regions and affected the cohesion of sister chromatids, thus affecting the arrangement of chromosomes in the metaphase plate and separation of chromatids in anaphase. In addition, these substances induced breaks in pericentromeric regions, characterized as fragile sites. Copyright © 2015 Elsevier Inc. All rights reserved.

  10. How Effective is Social Media as the Main Marketing Tool for Small and Medium-Sized Enterprises? : Case: WeLoveSpain

    OpenAIRE

    Al-Sadani, Abdulwahab

    2015-01-01

    The thesis will study the effectiveness of social media marketing as the main marketing tool for an SME. Social media has shown significant growth in popularity lately, both in the public and personal use as well as in the business world. Companies are acknowledging the potential of social media and realizing slowly that it seems that it will not be a passing trend. For an SME this could potentially mean good news. The general idea is that social media marketing could potentially be fairly in...

  11. Turbine main engines

    CERN Document Server

    Main, John B; Herbert, C W; Bennett, A J S

    1965-01-01

    Turbine Main Engines deals with the principle of operation of turbine main engines. Topics covered include practical considerations that affect turbine design and efficiency; steam turbine rotors, blades, nozzles, and diaphragms; lubricating oil systems; and gas turbines for use with nuclear reactors. Gas turbines for naval boost propulsion, merchant ship propulsion, and naval main propulsion are also considered. This book is divided into three parts and begins with an overview of the basic mode of operation of the steam turbine engine and how it converts the pressure energy of the ingoing ste

  12. Is cost-effectiveness analysis preferred to severity of disease as the main guiding principle in priority setting in resource poor settings? The case of Uganda

    Directory of Open Access Journals (Sweden)

    Norheim Ole

    2004-01-01

    Full Text Available Abstract Introduction Several studies carried out to establish the relative preference of cost-effectiveness of interventions and severity of disease as criteria for priority setting in health have shown a strong preference for severity of disease. These preferences may differ in contexts of resource scarcity, as in developing countries, yet information is limited on such preferences in this context. Objective This study was carried out to identify the key players in priority setting in health and explore their relative preference regarding cost-effectiveness of interventions and severity of disease as criteria for setting priorities in Uganda. Design 610 self-administered questionnaires were sent to respondents at national, district, health sub-district and facility levels. Respondents included mainly health workers. We used three different simulations, assuming same patient characteristics and same treatment outcome but with varying either severity of disease or cost-effectiveness of treatment, to explore respondents' preferences regarding cost-effectiveness and severity. Results Actual main actors were identified to be health workers, development partners or donors and politicians. This was different from what respondents perceived as ideal. Above 90% of the respondents recognised the importance of both severity of disease and cost-effectiveness of intervention. In the three scenarios where they were made to choose between the two, a majority of the survey respondents assigned highest weight to treating the most severely ill patient with a less cost-effective intervention compared to the one with a more cost-effective intervention for a less severely ill patient. However, international development partners in in-depth interviews preferred the consideration of cost-effectiveness of intervention. Conclusions In a survey among health workers and other actors in priority setting in Uganda, we found that donors are considered to have more say than

  13. Modeling Temporal Behavior of Awards Effect on Viewership of Movies

    KAUST Repository

    Altaf, Basmah

    2017-04-22

    The “rich get richer” effect is well-known in recommendation system. Popular items are recommended more, then purchased more, resulting in becoming even more popular over time. For example, we observe in Netflix data that awarded movies are more popular than non-awarded movies. Unlike other work focusing on making fair/neutralized recommendation, in this paper, we target on modeling the effect of awards on the viewership of movies. The main challenge of building such a model is that the effect on popularity changes over time with different intensity from movie to movie. Our proposed approach explicitly models the award effects for each movie and enables the recommendation system to provide a better ranked list of recommended movies. The results of an extensive empirical validation on Netflix and MovieLens data demonstrate the effectiveness of our model.

  14. Effects of the Natural β-Carboline Alkaloid Harmine, a Main Constituent of Ayahuasca, in Memory and in the Hippocampus: A Systematic Literature Review of Preclinical Studies.

    Science.gov (United States)

    Dos Santos, Rafael G; Hallak, Jaime E C

    2017-01-01

    Harmine is a natural β-carboline alkaloid found in several botanical species, such as the Banisteriopsis caapi vine used in the preparation of the hallucinogenic beverage ayahuasca and the seeds of Syrian rue (Peganum harmala). Preclinical studies suggest that harmine may have neuroprotective and cognitive-enhancing effects, and retrospective/observational investigations of the mental health of long-term ayahuasca users suggest that prolonged use of this harmine-rich hallucinogen is associated with better neuropsychological functioning. Thus, in order to better investigate these possibilities, we performed a systematic literature review of preclinical studies analyzing the effects of harmine on hippocampal neurons and in memory-related behavioral tasks in animal models. We found two studies involving hippocampal cell cultures and nine studies using animal models. Harmine administration was associated with neuroprotective effects such as reduced excitotoxicity, inflammation, and oxidative stress, and increased brain-derived neurotrophic factor (BDNF) levels. Harmine also improved memory/learning in several animal models. These effects seem be mediated by monoamine oxidase or acetylcholinesterase inhibition, upregulation of glutamate transporters, decreases in reactive oxygen species, increases in neurotrophic factors, and anti-inflammatory effects. The neuroprotective and cognitive-enhancing effects of harmine should be further investigated in both preclinical and human studies.

  15. Maine highway safety plan

    Science.gov (United States)

    2010-01-01

    Each September 1, the MeBHS must provide NHTSA a comprehensive plan to reduce : traffic crashes and resulting deaths, injuries and property damage. The Highway Safety : Plan (HSP) serves as Maines application for available federal funds for these ...

  16. Maine Field Station

    Data.gov (United States)

    Federal Laboratory Consortium — In 2000 NOAA's National Marine Fisheries Service established the Maine Field Station in Orono, ME to have more direct involvement in the conservation of the living...

  17. Modelling irradiation effect of EUROFER

    International Nuclear Information System (INIS)

    Boutard, J.-L.; Dudarev, S.; Victoria, M.

    2006-01-01

    In fusion power reactor, the properties that controlled the behaviour of materials are affected at the atom scale: (i) the crystalline structure is locally destroyed where a displacement cascade occurs, (ii) the chemical bond is affected by transmutation products such as He and H, (iii) an radiation induced microstructure will take place due the diffusion of these point defects and impurities EFDA has launched a programme since 2002 to develop and validate modelling tools to predict the radiation effects in the reference ferritic martensitic steel Eurofer. Up to now, the effort has been devoted (i) to validate the multi-scale modelling approach based on ab-initio energetics map of point defects and He, (iii) to develop inter-atomic potentials for Molecular Dynamics simulation of displacement cascades and dislocation dynamics. Formation and migration energies and diffusion mechanisms of small vacancy (n< ) and interstitial clusters (n< ) were computed with the ab-initio code SIESTA and used to successfully predict via Kinetic Monte Carlo the experimental recovery stages of radiation damage in ultra high purity Fe. A complete He and point defect energetics mapping was ab-initio determined in Fe-C and used to reproduce via Rate Theory He-desorption from pre-implanted specimens. A developed '' magnetic '' potential is capable of transferring the magnetic properties of Fe due to the 3d-electron correlation to the scale of the Molecular Dynamics. An inter-atomic potential is being developed to reproduce the thermodynamics of the Fe-Cr system. The program will now be devoted (i) to develop atom-scale reference kinetic methods to predict the phase - stability of the Fe-Cr thermally and under irradiation (ii) to predict at the atom scale the core structure and dynamics of screw dislocation and their collective behaviour at the meso-scale, using Discrete Dislocation Dynamics (iii) to validate at the relevant scale using the multi-beam CEA-CNRS facility JANNUS. JANNUS allows

  18. Maine's forests 2008

    Science.gov (United States)

    George L. McCaskill; William H. McWilliams; Charles J. Barnett; Brett J. Butler; Mark A. Hatfield; Cassandra M. Kurtz; Randall S. Morin; W. Keith Moser; Charles H. Perry; Christopher W. Woodall

    2011-01-01

    The second annual inventory of Maine's forests was completed in 2008 after more than 3,160 forested plots were measured. Forest land occupies almost 17.7 million acres, which represents 82 percent of the total land area of Maine. The dominant forest-type groups are maple/beech/yellow birch, spruce/fir, white/red/jack pine, and aspen/white birch. Statewide volume...

  19. Maine Forests 2013

    Science.gov (United States)

    George L. McCaskill; Thomas Albright; Charles J. Barnett; Brett J. Butler; Susan J. Crocker; Cassandra M. Kurtz; William H. McWilliams; Patrick D. Miles; Randall S. Morin; Mark D. Nelson; Richard H. Widmann; Christopher W. Woodall

    2016-01-01

    The third 5-year annualized inventory of Maine's forests was completed in 2013 after more than 3170 forested plots were measured. Maine contains more than 17.6 million acres of forest land, an area that has been quite stable since 1960, covering more than 82 percent of the total land area. The number of live trees greater than 1 inch in diameter are approaching 24...

  20. ANALISIS OF THE INFLUENCE OF THE MAIN PARAMETERS AND CONDITION OF WORK OF AIRCRAFT CESN ON THE EFFICENCY OF THEIR USE METHODS OF MATHEMATICAL MODELING

    Directory of Open Access Journals (Sweden)

    Vladimir I. Troitsky

    2018-01-01

    Full Text Available The article describes the results of the numerical experiments on the mathematical model of the correlation-extreme navigation system (CESN of the aircraft (LA using microwave radiation of the earth's cover. The aim of the numerical experiments was the analysis of the influence of the main parameters (characteristics of the radiometer and antenna, a means of reviewing the space, parameters of the current image and the reference image, methods for image processing (algorithms for image correlation, conditions of the equipment operation (the speed and altitude of aircraft, the evolution of media on the efficiency of CESN. The experiments were carried out with the fields of the underlying surface of three types-with an artificially synthesized map (CLAIM containing several objects of different thermal contrast; with a homogeneous random field (OSP, with fragments of a digital map object structure (TSKOS of real surface area of the earth. As a result of numerical experiments the author studied the influence on exactness characteristics of CESN navigation parameters (bank angles, pitch, yaw, flight altitude and speed, the noise of the radiometer, the pattern width, the width of the review sector, mis-scaling and angular misalignment of the current and reference images. Comparison of different methods of surface scanning was made based on the simulation results. During the experiments, the variation of one of the parameters with respect to the base variants of the parameters was carried out and the values and variances of errors of the CESN were estimated. All three main methods of beam scanning (longitudinal with a multi-beam radiometer, conical and transverse were considered. The operation of the maximum search was made up of two procedures: searching for the global maximum area of the correlation matrix by enumerating all matrix entries and refining the location of the true maximum point by quadratic interpolation of the function. The

  1. [Carbon storage of forest vegetation and allocation for main forest types in the east of Da-xing'an Mountains based on additive biomass model].

    Science.gov (United States)

    Peng, Wei; Dong, Li Hu; Li, Feng Ri

    2016-12-01

    Based on the biomass investigation data of main forest types in the east of Daxing'an Mountains, the additive biomass models of 3 main tree species were developed and the changes of carbon storage and allocation of forest community of tree layer, shrub layer, herb layer and litter layer from different forest types were discussed. The results showed that the carbon storage of tree layer, shrub layer, herb layer and litter layer for Rhododendron dauricum-Larix gmelinii forest was 71.00, 0.34, 0.05 and 11.97 t·hm -2 , respectively. Similarly, the carbon storage of the four layers of Ledum palustre-L. gmelinii forest was 47.82, 0.88, 0, 5.04 t·hm -2 , 56.56, 0.44, 0.04, 8.72 t·hm -2 for R. dauricum-mixed forest of L. gmelinii-Betula platyphylla, 46.21, 0.66, 0.07, 6.16 t·hm -2 for L. palustre-mixed forest of L. gmelinii-B. platyphylla, 40.90, 1.37, 0.04, 3.67 t·hm -2 for R. dauricum-B. platyphylla forest, 36.28, 1.12, 0.18, 4.35 t·hm -2 for L. palustre-B. platyphylla forest. The carbon storage of forest community for the understory vegetation of R. dauricum was higher than that of the forest with L. palustre. In the condition of similar circumstances for the understory, the order of carbon storage for forest community was L. gmelinii forest > the mixed forest of L. gmelinii-B. platyphylla > B. platyphylla forest. The carbon storage of different forest types was different with the order of R. dauricum-L. gmelinii forest (83.36 t·hm -2 )> R. dauricum-mixed forest of L. gmelinii-B. platyphylla (65.76 t·hm -2 ) > L. palustre-L. gmelinii forest (53.74 t·hm -2 )> L. palustre-mixed forest of L. gmelinii-B. platyphylla (53.10 t·hm -2 )> R. dauricum-B. platyphylla forest (45.98 t·hm -2 ) > L. palustre-B. platyphylla forest (41.93 t·hm -2 ). The order of carbon storage for the vertical distribution in forest communities with diffe-rent forest types was the tree layer (85.2%-89.0%) > litter layer (8.0%-14.4%) > shrub layer (0.4%-2.7%) > herb layer (0-0.4%).

  2. Autoconceito dos professores: principais factores usando modelos de Análise de Dados Multivariada Teachers' self-concept: finding main factors and clusters by EDA models

    Directory of Open Access Journals (Sweden)

    Vitor Franco

    2008-01-01

    Full Text Available O autoconceito tem sido considerado uma dimensão muito importante da personalidade do professor, da sua prática e do seu desenvolvimento pessoal (MARKUS; WURF, 1987; SIMÕES, 2001. A investigação que apresentamos foi efectuada com 281 professores de Ciências da Natureza, do terceiro ciclo do Ensino Básico, em Portugal, usando o ICAC- Inventário Clínico do Auto Conceito (VAZ-SERRA, 1986. Na análise dos dados obtidos foram usados diferentes métodos de Análise Multivariada, apresentando-se os resultados da análise factorial de correspondências e nos modelos de classificação hierárquica baseados no coeficiente de afinidade. Os resultados obtidos: 1 confirmam a importância de dois grandes factores presentes no Autoconceito: aceitação social e auto-eficácia; 2 caracterizam estes principais factores no que se refere ao Autoconceito clínico dos professores; 3 mostram como esses factores são determinantes na forma como cada professor constroi o seu autoconceito.The self-concept has been considered as a very important dimension on teacher's personality, practice and development (MARKUS; WURF, 1987;SIMÕES, 2001. The present research concerns a sample of 281 teachers of Natural Science of the Third Cycle of Basic Education from Portugal that responded to the I.C.A.C. - Self-Concept Clinical Inventory (VAZ-SERRA, 1986. In the analysis of the questionnaires different multivariate data analysis methods have been used. This paper describes some results issued from correspondence analysis and hierarchical clustering models based on the affinity coefficient. The results obtained: 1 confirm the importance of two general main factors / types which are present in self-concept: social acceptance and self-efficiency; 2 characterise these main factors when teachers'clinical self-concept is concerned and 3 show how determinant these factors are for the building of self-concept that allow us to differentiate teachers.

  3. Modelling the effect of land use change on hydrological model ...

    African Journals Online (AJOL)

    Modelling the effect of land use change on hydrological model parameters via linearized calibration method in the upstream of Huaihe River Basin, China. ... is presented, based on the analysis of the problems of the objective function of the ...

  4. Effect of hydrogen peroxide on the main kinetic parameters of ATP hydrolysis by ouabain sensitive Na+, K+-ATP-ase in spermatozoa of infertile men

    Directory of Open Access Journals (Sweden)

    Р. В. Фафула

    2017-12-01

    Full Text Available Background: It is known that Na+,K+-ATP-ase plays important role in physiology of spermatozoa including their motility. Na+,K+-ATP-ase is one of the targets for reactive oxygen species. Hyperproduction of reactive oxygen species can damage sperm cells and it is considered to be as one of the mechanisms of male infertility. Objectives: To evaluate the H2O2 effect on the main kinetic parameters of ATP hydrolysis by ouabain-sensitive Na+,K+-ATPase of spermatozoa of fertile (normozoospermia and infertility men (asthenozoospermia. Materials and methods: Na+, K+-ATP-ase activity was determined spectrophotometrically by production of Pi. Concentration dependencies ware linearized in Lineweaver-Burk plot. Results: Effective inhibitory effect of H2O2 on ouabain-sensitive Na+,K+-ATP-ase activity of sperm cells of fertile and infertile men was demonstrated. The effects of H2O2 on the main kinetic parameters of the ATP hydrolysis with the involvement of Na+, K+-ATP-ase was studied. In the whole range of studied concentrations of ATP the Na+, K+-ATP-ase activity of spermatozoa of fertile and infertile men was reduced in the presence of H2O2 in the incubation medium. However, the optimal activity of the Na+, K+-ATP-ase activity of sperm cells in both normozoospermic and asthenozoospermic men was observed in the presence of 5 mM ATP in the incubation medium. By linearization of concentration curves in Lineweaver-Burk plot the main kinetic parameters of Na+, K+-activated, Mg2+-dependent ATP hydrolysis in the sperm cells of fertile and infertile men were determined. Under the effect of H2O2, the affinity constant of enzyme to ATP in normozoospermic and asthenozoospermic men increases several times. The initial maximum rate of ATP hydrolysis was significantly reduced only in the spermatozoa of fertile men with normozoospermia. Conclusions: Under conditions of H2O2-induced oxidative stress the inhibition of ouabain-sensitive Na+,K+-ATP-ase activity in sperm cells

  5. OECD/NEZ Main Steam Line Break Benchmark Problem Exercise I Simulation Using the SPACE Code with the Point Kinetics Model

    International Nuclear Information System (INIS)

    Kim, Yohan; Kim, Seyun; Ha, Sangjun

    2014-01-01

    The Safety and Performance Analysis Code for Nuclear Power Plants (SPACE) has been developed in recent years by the Korea Nuclear Hydro and Nuclear Power Co. (KHNP) through collaborative works with other Korean nuclear industries. The SPACE is a best-estimated two-phase three-field thermal-hydraulic analysis code to analyze the safety and performance of pressurized water reactors (PWRs). The SPACE code has sufficient features to replace outdated vendor supplied codes and to be used for the safety analysis of operating PWRs and the design of advanced reactors. As a result of the second phase of the development, the 2.14 version of the code was released through the successive various V and V works. The topical reports on the code and related safety analysis methodologies have been prepared for license works. In this study, the OECD/NEA Main Steam Line Break (MSLB) Benchmark Problem Exercise I was simulated as a V and V work. The results were compared with those of the participants in the benchmark project. The OECD/NEA MSLB Benchmark Problem Exercise I was simulated using the SPACE code. The results were compared with those of the participants in the benchmark project. Through the simulation, it was concluded that the SPACE code can effectively simulate PWR MSLB accidents

  6. Research progress of Tribulus terrestris composition and main pharmaco-logic effects%蒺藜成分及主要药理作用研究进展

    Institute of Scientific and Technical Information of China (English)

    候爽; 陈长军; 杨博; 于飞飞; 崔晓莉; 孟雨; 田洪艳; 李质馨

    2014-01-01

    Traditional Chinese medicine (TCM) Tribulus terrestris contains a variety of important biological active substances, such as saponins, flavonoids and other compounds, which has many pharmacological effects. Modern medi-cal research indicates that Tribulus terrestris can remarkably delay senescence, reduce blood glucose and blood lipid, strengthen sexual function and enhance the sex hormones in the human body, etc. And it has good curative effects for cancer, high blood pressure, bacteria and fungal infections, diabetes and etc. This article mainly discusses the research progress on Tribulus terrestris composition and its main pharmacological activities in recent years.%中药蒺藜中含有多种重要的生物活性物质如皂苷类、黄酮类等的化合物,具有众多的药理作用。现代医学研究证明,蒺藜具有显著的抗衰老、降血糖、降血脂、性强壮及提高人体中性激素含量等的作用,对肿瘤、高血压、细菌真菌感染、糖尿病等均有较好疗效。本文主要对近年来中药蒺藜成分及主要药理作用研究进展进行综述。

  7. Effects of growing location on the production of main active components and antioxidant activity of Dasiphora fruticosa (L.) Rydb. by chemometric methods.

    Science.gov (United States)

    Liu, Wei; Wang, Dongmei; Hou, Xiaogai; Yang, Yueqin; Xue, Xian; Jia, Qishi; Zhang, Lixia; Zhao, Wei; Yin, Dongxue

    2018-05-17

    Traditional Chinese medicine (TCM) plays a very important role in the health system of China. The content and activity of active component are main indexes that evaluate the quality of TCM, however they may vary with environmental factors in their growing locations. In this study, effects of environmental factors on the contents of active components and antioxidant activity of Dasiphora fruticosa from the five main production areas of China were investigated. The contents of tannin, total flavonoid and rutin were determined and varied within the range of 7.65-10.69%, 2.30-5.39% and 0.18-0.81%, respectively. Antioxidant activity was determined by DPPH assay, with the DPPH IC 50 values ranged from 8.791 to 32.534μg mL -1 . In order to further explore the cause of these significant geographical variations, the chemometric methods including correlation analysis, principal component analysis, gray correlation analysis, and path analysis were conducted. The results showed environmental factors had significant effect on the active component contents and antioxidant activity. Rapidly available phosphorus (RAP) and rapidly available nitrogen (RAN) were common dominant factors, and a significant positive correlation was observed between RAP and active components and antioxidant activity (Pcomponents and strong antioxidant activity, Bange in Tibet and Geermu in Qinghai Province was selected as a favorable growing location, respectively. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

  8. Main sequence mass loss

    International Nuclear Information System (INIS)

    Brunish, W.M.; Guzik, J.A.; Willson, L.A.; Bowen, G.

    1987-01-01

    It has been hypothesized that variable stars may experience mass loss, driven, at least in part, by oscillations. The class of stars we are discussing here are the δ Scuti variables. These are variable stars with masses between about 1.2 and 2.25 M/sub θ/, lying on or very near the main sequence. According to this theory, high rotation rates enhance the rate of mass loss, so main sequence stars born in this mass range would have a range of mass loss rates, depending on their initial rotation velocity and the amplitude of the oscillations. The stars would evolve rapidly down the main sequence until (at about 1.25 M/sub θ/) a surface convection zone began to form. The presence of this convective region would slow the rotation, perhaps allowing magnetic braking to occur, and thus sharply reduce the mass loss rate. 7 refs

  9. Comparison of Power Generating Systems Using Feedback Effect Modeling

    International Nuclear Information System (INIS)

    Kim, Seong Ho; Kim, Kil Yoo; Kim, Tae Woon

    2005-01-01

    Comparative assessment of various power systems can be treated as a multicriteria decision-making (MCDM) problem. In reality, there is interdependence among decision elements (e.g., decision goal, decision criteria, and decision alternatives). In our previous work, using an analytic hierarchy process (AHP) technique, a comprehensive assessment framework for national power systems has been developed. It was assumed in the AHP modeling that there is no interdependence among decision elements. In the present work, one of interdependence phenomena, feedback effect, is investigated in the context of network structures instead of one-way directional tree structures. Moreover, attitudes of decision-makers can be incorporated into the feedback effect modeling. The main objectives of this work are to develop a feedback effect modeling using an analytic network process (ANP) technique and to demonstrate the feedback effect using a numerical example in comparison to the hierarchy model

  10. [Ecological effects of wheat-oilseed rape intercropping combined with methyl salicylate release on Sitobion avenae and its main natural enemies].

    Science.gov (United States)

    Dong, Jie; Liu, Ying-Jie; Li, Pei-Ling; Lin, Fang-Jing; Chen, Ju-Lian; Liu, Yong

    2012-10-01

    In order to explore the effects of wheat-oilseed rape intercropping in combining with methyl salicylate (MeSA) release on Sitobion avenae and its main natural enemies, a field experiment was conducted at the Tai'an Experimental Station of Shandong Agricultural University in East China from October 2008 to June 2010 to study the temporal dynamics of S. avenae and its main natural enemies as well as the ecological control effect on the aphid. In the plots of intercropping combined with MeSA release, the S. avenae apterae population reached a peak about 12 d in advance of the control, but the peak value was significantly lower than that of the control. The average annual number of S. avenae apterae per 100 wheat tillers decreased in the order of wheat monoculture > wheat-oilseed rape intercropping > MeSA release > wheat-oilseed rape intercropping combined with MeSA release. Moreover, the total number of ladybeetles was the highest in the plots of intercropping combined with MeSA release. The population densities of aphid parasitoids reached a peak about 10 d in advance of the control, which could play a significant role in controlling S. avenae at the filling stage of wheat. Taking the biological control index (BCI) as a quantitative indicator, and with the ladybeetles and parasitoids as the dominant control factors in fields, it was observed that wheat-oilseed rape intercropping combined with MeSA release could suppress the population increase of S. avenae apterae effectively from the heading to filling stages of wheat.

  11. Main: FBB2 [TP Atlas

    Lifescience Database Archive (English)

    Full Text Available ion of the c-ring - A subunit packing model of E. coli c-ring has been proposed - The main chain secondary s...tructure of thermophile c-ring has been obtained ATP synthase is a general term for an enzyme that can synth

  12. Comparison of branch and distally focused main renal artery denervation using two different radio-frequency systems in a porcine model.

    Science.gov (United States)

    Mahfoud, Felix; Pipenhagen, Catherine A; Boyce Moon, L; Ewen, Sebastian; Kulenthiran, Saarraaken; Fish, Jeffrey M; Jensen, James A; Virmani, Renu; Joner, Michael; Yahagi, Kazuyuki; Tsioufis, Costas; Böhm, Michael

    2017-08-15

    Anatomic placement of lesions may impact efficacy of radio-frequency (RF) catheter renal denervation (RDN). However, it is unclear if it is necessary to perform treatments post bifurcation with systems that may provide deeper penetration to achieve successful RDN. Sixteen domestic swine (n=16) were randomly assigned to 4 groups: 1) 8 lesions created in the branch arteries using the Spyral catheter (SP8); 2) 8 lesions created in the branch arteries plus 4 lesions created in the main artery using the SP catheter (SP12); 3) 8 lesions created in the main artery using the EnligHTN catheter with the distal position as close as possible to the bifurcation (EN8); and 4) 12 lesions created in the main artery using the EN catheter with the distal position as close as possible to the bifurcation (EN12). Each arm showed statistically significant changes in kidney norepinephrine (NE, ng/g) between treated kidneys vs. untreated contralateral control. There were no statistically significant differences in tissue NE% reductions across each arm based on catheter, anatomic location, & number of lesions (p=0.563): EN8 -74±34%, EN12 -95±3%, SP8 -76±16%, SP12 -82±17% (p=0.496). A total of 46 lesions were measured for lesion depth: EN main (3.3±2.8mm) vs. SP branch (2.0±1.0mm, p=0.039), SP main (2.9±1.6mm) vs. SP branch (p=0.052), and EN main vs. SP main (p=0.337). Distally-focused main renal artery treatment using the EN system appears to be equally efficacious in reducing tissue NE levels compared with SP treatment in the branches plus main renal arteries, advocating for device-specific procedure execution. Copyright © 2017 Elsevier B.V. All rights reserved.

  13. Evaluation of the Use of Different Solvents to Extract the Four Main Components of Yinqiaosan and Their In Vitro Inhibitory Effects on Influenza-A Virus

    Directory of Open Access Journals (Sweden)

    Xuefeng Wang

    2010-04-01

    Full Text Available High-performance liquid chromatography coupled with an ultraviolet detector was used to quantitatively determine the amount of caffeoylquinic acid, arctium lappa glycoside, aurantiamarin and forsythin present in five solvent extracts (water, 30% ethanol, 50% ethanol, 70% ethanol and 95% ethanol of Yinqiaosan (YQS. The calibration curves of the four components were linear (r2 > 0.998 over the concentration range of 0.9–151.5 μg/mL. This method showed good repeatability with relative standard deviations of less than 2.9% and mean recoveries of 91.3–100.5%. We established the relative amounts of each of the four main ingredients in YQS for all five solvent extracts. The direct inhibitory effects of the five YQS extracts on influenza-A virus in vitro and the therapeutic effects on infected embryonated hen eggs were evaluated. YQS extracted in 50% ethanol and used at concentrations of 500mg/mL and 250mg/mL exerted the greatest therapeutic effect in infected embryonated hen eggs and was significantly superior to ribavirin (p < 0.05. Therefore, the 50% ethanol extract of YQS seems to be the most effective for the inhibition of influenza-A virus. Based on these results, further studies are warranted to evaluate the use of YQS extracts as a possible therapy for influenza.

  14. A Departmental Cost-Effectiveness Model.

    Science.gov (United States)

    Holleman, Thomas, Jr.

    In establishing a departmental cost-effectiveness model, the traditional cost-effectiveness model was discussed and equipped with a distant and deflation equation for both benefits and costs. Next, the economics of costing was examined and program costing procedures developed. Then, the model construct was described as it was structured around the…

  15. The Main Determinants of Improvement of Model of Educational Training of Specialists in the Field of PR Based on Competency Approach

    Directory of Open Access Journals (Sweden)

    Andrii Kyrychok

    2017-07-01

    Full Text Available Modern approaches to the study of issue of PR-experts training require rethinking in order to identify new prospects of improvement and development in training of specialists in public relations. An important aspect is that Ukraine has recently moved to training format, based on acquiring of knowledge necessary for professional life by students. This applies, in particular, to specialists in public relations. The key aspect is to determine the set of skills of PR-specialist meant to be acquired by him during study. Another important point is the transition to the European three-level educational model, aimed at democratization and improvement of the process of acquiring of necessary skills by specialists. The essential transformation should be done in the field of PR-education in order to allow experts, at every level of education (Bachelor-Master-PhD, to receive only a clearly defined and systematic set of skills. The author carried out the content analysis of educational training programs in the field of PR for the purpose of discipline component, the principles of programming and knowledge, acquired at each educational level. Investigated data was systematized, analysed and recommendations on principles of development of effective three-level model of training for experts in public relations at the university were given.

  16. Distress after a psychosocial cancer rehabilitation course. Main effects and effect modification in a randomised trial at 12 months of follow-up

    DEFF Research Database (Denmark)

    Ross, Lone; Rottmann, Nina; Andersen, Klaus K.

    2015-01-01

    within the past two years who had completed primary treatment were randomised to a six-day, multidimensional residential rehabilitation course or to standard care. Of these, 208 patients received the allocated intervention and 244 received the allocated control condition and were included in the analyses....... Patients in both groups completed questionnaires at baseline and at one, six and 12 months of follow-up, including the 'Profile of Mood States short form', the 'General Self-efficacy' scale and a question on emotional support. At 12 months of follow-up, 179 participants in the intervention group and 195...... programmes may not be effective in the treatment of distress. During the past few decades, studies of psychotherapy or psycho-education in cancer patients have shown small to moderate effects. More focused rehabilitation programmes may be more effective....

  17. FERMILAB: Main Injector

    International Nuclear Information System (INIS)

    Anon.

    1993-01-01

    The Fermilab Main Injector (FMI) project is the centerpiece of the Laboratory's Fermilab III programme for the 1990s. Designed to support a luminosity of at least 5x10 31 cm -2 s -1 in the Tevatron collider, it will also provide new capabilities for rare neutral kaon decay and neutrino oscillation studies. The Fermilab Main Injector 8-150 GeV synchrotron is designed to replace the existing Main Ring which seriously limits beam intensities for the Tevatron and the antiproton production target. The project has passed several significant milestones and is now proceeding rapidly towards construction. The project received a $11.65M appropriation in 1992 and has been given $15M for the current fiscal year. Through the Energy Systems Acquisition Advisory Board (ESAAB) process, the US Department of Energy (DoE) has authorized funds for construction of the underground enclosure and service building where the Main Injector will touch the Tevatron, and to the preparation of bids for remaining project construction

  18. FERMILAB: Main Injector

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    1993-06-15

    The Fermilab Main Injector (FMI) project is the centerpiece of the Laboratory's Fermilab III programme for the 1990s. Designed to support a luminosity of at least 5x10{sup 31} cm{sup -2} s{sup -1} in the Tevatron collider, it will also provide new capabilities for rare neutral kaon decay and neutrino oscillation studies. The Fermilab Main Injector 8-150 GeV synchrotron is designed to replace the existing Main Ring which seriously limits beam intensities for the Tevatron and the antiproton production target. The project has passed several significant milestones and is now proceeding rapidly towards construction. The project received a $11.65M appropriation in 1992 and has been given $15M for the current fiscal year. Through the Energy Systems Acquisition Advisory Board (ESAAB) process, the US Department of Energy (DoE) has authorized funds for construction of the underground enclosure and service building where the Main Injector will touch the Tevatron, and to the preparation of bids for remaining project construction.

  19. Main facts 1995

    International Nuclear Information System (INIS)

    1996-01-01

    This report presents the main facts of the studies carried out by the Direction des Etudes et Recherches (DER) of Electricite de France: new applications of electricity, classical and nuclear thermal power plants, electrical equipment, environment protection, monitoring and plants operations

  20. Main designations and attributions

    International Nuclear Information System (INIS)

    2010-01-01

    The chapter presents the main designations and attributions of the LNMRI - Brazilian National Laboratory of Metrology of Ionizing Radiation, the Cooperative Center in Radiation Protection and Medical Preparations for Accidents with Radiation; the Treaty for fully banning of nuclear tests and the Regional Center for Training of IAEA

  1. Maine Bouguer Gravity Grid

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — A 2 kilometer Bouguer anomaly grid for the state of Maine. Number of columns is 197 and number of rows is 292. The order of the data is from the lower left to the...

  2. Main facts 1993

    International Nuclear Information System (INIS)

    1994-01-01

    This report presents the main facts of the studies carried out by the Direction des Etudes et Recherches (DER) of Electricite de France: new applications of electricity, classical and nuclear thermal power plants, electrical equipment, environment protection, network analysis, information and informatic equipment

  3. MOS modeling hierarchy including radiation effects

    International Nuclear Information System (INIS)

    Alexander, D.R.; Turfler, R.M.

    1975-01-01

    A hierarchy of modeling procedures has been developed for MOS transistors, circuit blocks, and integrated circuits which include the effects of total dose radiation and photocurrent response. The models were developed for use with the SCEPTRE circuit analysis program, but the techniques are suitable for other modern computer aided analysis programs. The modeling hierarchy permits the designer or analyst to select the level of modeling complexity consistent with circuit size, parametric information, and accuracy requirements. Improvements have been made in the implementation of important second order effects in the transistor MOS model, in the definition of MOS building block models, and in the development of composite terminal models for MOS integrated circuits

  4. Possible effects of the Worldwide production of ethanol in two of the main countries that imports corn. South Korea and Mexico

    Directory of Open Access Journals (Sweden)

    Saúl Martínez González

    2010-01-01

    Full Text Available South Korea is the second largest importer of corn and Mexico is the third. Although the corn has its origin in this country, since 1994 Mexico has become one of the major importers in the world. This essay examines the possible economic implications for Mexico and Korea for the increased production of ethanol from corn. The analysis parts of the close relationship of three interconnected problems, which are at the root of the current energy crisis: global warming, oil crisis and biofuel production. This is causing a global food crisis. The production of ethanol from corn is emerging as an alternative that may address global warming and attacking the alleged shortage of oil, which has resulted in rising prices. The point in discussion is what are the possible effects of policies to induce the production of biofuels (ethanol on the main importers of corn. That’s why the current status of the ethanol industry is analyzed, whose main protagonists on the world stage are the United States and Brazil. Then we made a brief analysis of the market of corn. Finally, based on the foregoing, we reflect on the possible implications it might have on the development of food production of etanol.

  5. Caspase-Mediated Anti-Apoptotic Effect of Ginsenoside Rg5, a Main Rare Ginsenoside, on Acetaminophen-Induced Hepatotoxicity in Mice.

    Science.gov (United States)

    Wang, Zi; Hu, Jun-Nan; Yan, Meng-Han; Xing, Jing-Jing; Liu, Wen-Cong; Li, Wei

    2017-10-25

    Frequent overdose of acetaminophen (APAP) is one of the most common and important incentives of acute hepatotoxicity. Prior to this work, our research group confirmed that black ginseng (Panax ginseng, BG) showed powerful protective effects on APAP-induced ALI. However, it is not clear which kind of individual ginsenoside from BG plays such a liver protection effect. The objective of the current investigation was to evaluate whether ginsenoside Rg5 (G-Rg5) protected against APAP-induced hepatotoxicity and the involved action mechanisms. Mice were administrated with G-Rg5 at two dosages of 10 or 20 mg/kg for 7 consecutive days. After the last treatment, all of the animals that received a single intraperitoneal injection of APAP (250 mg/kg) showed severe liver toxicity after 24 h, and the liver protection effects of G-Rg5 were examined. The results clearly indicated that pretreatment with G-Rg5 remarkably inhibited the production of serum tumor necrosis factor (TNF-α) and interleukin-1β (IL-1β) compared with the APAP group. Meanwhile, G-Rg5 decreased the hepatic malondialdehyde (MDA) content, the protein expression levels of 4-hydroxynonenal (4-HNE) and cytochrome P450 2E1 (CYP2E1) in the liver tissues. G-Rg5 decreased APAP caused the hepatic overexpression of cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS). Furthermore, analysis of immunohistochemistry and Western blotting also indicated that G-Rg5 pretreatment inhibited activation of apoptotic pathways mainly via increasing the expression of Bcl-2 protein, decreasing the expression of Bax protein, proliferating cell nuclear antigen (PCNA), cytochrome c, caspase-3, caspase-8, and caspase-9. Liver histopathological observation provided further evidence that pretreatment with G-Rg5 could significantly inhibit hepatocyte necrosis, inflammatory cell infiltration, and apoptosis caused by APAP. In conclusion, the present study clearly demonstrates that G-Rg5 exerts a liver protection effect against

  6. The differential susceptibility to media effects model

    NARCIS (Netherlands)

    Valkenburg, P.M.; Peter, J.

    2013-01-01

    In this theoretical article, we introduce the Differential Susceptibility to Media Effects Model (DSMM), a new, integrative model to improve our understanding of media effects. The DSMM organizes, integrates, and extends the insights developed in earlier microlevel media-effects theories. It

  7. Elicitation effect of Saccharomyces cerevisiae yeast extract on main health-promoting compounds and antioxidant and anti-inflammatory potential of butter lettuce (Lactuca sativa L.).

    Science.gov (United States)

    Złotek, Urszula; Świeca, Michał

    2016-05-01

    This paper presents a study on changes in the main phytochemical levels and antioxidant and anti-inflammatory activity of lettuce caused by different doses and times of application of yeast extracts. Elicitation with yeast extract caused an increase in the total phenolic compounds and chlorophyll content, which varied according to the dose and time of spraying, but it did not have a positive impact on vitamin C, flavonoid and carotenoid content in lettuce. The best effect was achieved by double spraying with 1% yeast extract and by single spraying with 0.1% yeast extract. The increase in phytochemical content was positively correlated with the antioxidant and anti-inflammatory activity of the studied lettuce leaves. Chicoric acid seems to be the major contributor to these antioxidant activities. Yeast extract may be used as a natural, environmentally friendly and safe elicitor for improving the health-promoting qualities of lettuce. © 2015 Society of Chemical Industry. © 2015 Society of Chemical Industry.

  8. Field and laboratory tests of etched track detectors for 222Rn: summer-vs-winter variations and tightness effects in Maine houses

    International Nuclear Information System (INIS)

    Hess, C.T.; Fleischer, R.L.; Turner, L.G.

    1985-01-01

    Effects of tightness of homes of bedrock character on indoor 222 Rn concentrations were sought in 70 homes in the state of Maine by means of four 6- to 8-month-long surveys over a 1.5-yr period. Laboratory experiments were also performed that document the reliability of the track etching system used for the measurements. In this survey the Rn in tight homes was on the average 3.5 times that in drafty ones, and areas with granitic bedrock led to homes having 2.3 times the Rn as for homes on chlorite-biotite-rich bedrock. Winter-to-summer ratios ranged from 0.5-7, and averaged 1.5, implying that surveys of individual homes require a full year of monitoring

  9. A Systematic Review of the Processes Underlying the Main and the Buffering Effect of Social Support on the Experience of Pain.

    Science.gov (United States)

    Che, Xianwei; Cash, Robin; Ng, Sin Ki; Fitzgerald, Paul; Fitzgibbon, Bernadette M

    2018-04-24

    This review aimed to explore the processes that underlie the main and the buffering effect of social support on decreased pain experience. The systematic review was conducted according to the PRISMA guidelines. Online databases of PubMed and PsycINFO were searched for peer-reviewed articles using keywords (("social support", OR "interpersonal", OR "social presence", OR "spouse", OR "couple", OR "marriage") AND "pain"). Articles were included if they examined the cognitive or behavioural processes linking social support to any aspects of reduced pain experience. The database search identified 38 studies, of which 33 were cognitive-behavioural studies and 5 were neurobiological. Cognitive-behavioural studies generated a total of 57 findings of the analgesic influence of social support. This effect was further categorized as social support decreasing the adverse influence of pain-related stress (28/44 findings), reappraising pain-related stress (7/9 findings), and facilitating coping attempts (2/4 findings). Of the 5 neurobiological studies, the influence of social support on pain reduction was associated with reduced neural and physiological stress systems in response to painful stimuli. This review presents evidence that the stress-buffering effect is more often able to account for the relationship between social support and pain experience. Moreover, findings suggest the critical significance of stress appraisal and attenuated stress systems in linking social support to aspects of reduced pain experience. Findings implicate the role of integrating perceived support and intimacy in support-oriented interventional trials for chronic pain.

  10. Rapid determination of retinoic acid and its main isomers in plasma by second-order high-performance liquid chromatography data modeling.

    Science.gov (United States)

    Teglia, Carla M; Cámara, María S; Goicoechea, Héctor C

    2014-12-01

    This paper reports the development of a method based on high-performance liquid chromatography (HPLC) coupled to second-order data modeling with multivariate curve resolution-alternating least-squares (MCR-ALS) for quantification of retinoic acid and its main isomers in plasma in only 5.5 min. The compounds retinoic acid (RA), 13-cis-retinoic acid, 9-cis-retinoic acid, and 9,13-di-cis-retinoic acid were partially separated by use of a Poroshell 120 EC-C18 (3.0 mm × 30 mm, 2.7 μm particle size) column. Overlapping not only among the target analytes but also with the plasma interferents was resolved by exploiting the second-order advantage of the multi-way calibration. A validation study led to the following results: trueness with recoveries of 98.5-105.9 % for RA, 95.7-110.1 % for 13-cis-RA, 97.1-110.8 % for 9-cis-RA, and 99.5-110.9 % for 9,13-di-cis-RA; repeatability with RSD of 3.5-3.1 % for RA, 3.5-1.5 % for 13-cis-RA, 4.6-2.7 % for 9-cis-RA, and 5.2-2.7 % for 9,13-di-cis-RA (low and high levels); and intermediate precision (inter-day precision) with RSD of 3.8-3.0 % for RA, 2.9-2.4 % for 13-cis-RA, 3.6-3.2 % for 9,13-di-cis-RA, and 3.2-2.9 % for 9-cis-RA (low and high levels). In addition, a robustness study revealed the method was suitable for monitoring patients with dermatological diseases treated with pharmaceutical products containing RA and 13-cis-RA.

  11. ⁹⁹mTc pyrene derivative complex causes double-strand breaks in dsDNA mainly through cluster-mediated indirect effect in aqueous solution.

    Directory of Open Access Journals (Sweden)

    Wei-Ju Chung

    Full Text Available Radiation therapy for cancer patients works by ionizing damage to nuclear DNA, primarily by creating double-strand breaks (DSB. A major shortcoming of traditional radiation therapy is the set of side effect associated with its long-range interaction with nearby tissues. Low-energy Auger electrons have the advantage of an extremely short effective range, minimizing damage to healthy tissue. Consequently, the isotope ⁹⁹mTc, an Auger electron source, is currently being studied for its beneficial potential in cancer treatment. We examined the dose effect of a pyrene derivative ⁹⁹mTc complex on plasmid DNA by using gel electrophoresis in both aqueous and methanol solutions. In aqueous solutions, the average yield per decay for double-strand breaks is 0.011±0.005 at low dose range, decreasing to 0.0005±0.0003 in the presence of 1 M dimethyl sulfoxide (DMSO. The apparent yield per decay for single-strand breaks (SSB is 0.04±0.02, decreasing to approximately a fifth with 1 M DMSO. In methanol, the average yield per decay of DSB is 0.54±0.06 and drops to undetectable levels in 2 M DMSO. The SSB yield per decay is 7.2±0.2, changing to 0.4±0.2 in the presence of 2 M DMSO. The 95% decrease in the yield of DSB in DMSO indicates that the main mechanism for DSB formation is through indirect effect, possibly by cooperative binding or clustering of intercalators. In the presence of non-radioactive ligands at a near saturation concentration, where radioactive Tc compounds do not form large clusters, the yield of SSB stays the same while the yield of DSB decreases to the value in DMSO. DSBs generated by ⁹⁹mTc conjugated to intercalators are primarily caused by indirect effects through clustering.

  12. ⁹⁹mTc pyrene derivative complex causes double-strand breaks in dsDNA mainly through cluster-mediated indirect effect in aqueous solution.

    Science.gov (United States)

    Chung, Wei-Ju; Cui, Yujia; Huang, Feng-Yun J; Tu, Tzu-Hui; Yang, Tzu-Sen; Lo, Jem-Mau; Chiang, Chi-Shiun; Hsu, Ian C

    2014-01-01

    Radiation therapy for cancer patients works by ionizing damage to nuclear DNA, primarily by creating double-strand breaks (DSB). A major shortcoming of traditional radiation therapy is the set of side effect associated with its long-range interaction with nearby tissues. Low-energy Auger electrons have the advantage of an extremely short effective range, minimizing damage to healthy tissue. Consequently, the isotope ⁹⁹mTc, an Auger electron source, is currently being studied for its beneficial potential in cancer treatment. We examined the dose effect of a pyrene derivative ⁹⁹mTc complex on plasmid DNA by using gel electrophoresis in both aqueous and methanol solutions. In aqueous solutions, the average yield per decay for double-strand breaks is 0.011±0.005 at low dose range, decreasing to 0.0005±0.0003 in the presence of 1 M dimethyl sulfoxide (DMSO). The apparent yield per decay for single-strand breaks (SSB) is 0.04±0.02, decreasing to approximately a fifth with 1 M DMSO. In methanol, the average yield per decay of DSB is 0.54±0.06 and drops to undetectable levels in 2 M DMSO. The SSB yield per decay is 7.2±0.2, changing to 0.4±0.2 in the presence of 2 M DMSO. The 95% decrease in the yield of DSB in DMSO indicates that the main mechanism for DSB formation is through indirect effect, possibly by cooperative binding or clustering of intercalators. In the presence of non-radioactive ligands at a near saturation concentration, where radioactive Tc compounds do not form large clusters, the yield of SSB stays the same while the yield of DSB decreases to the value in DMSO. DSBs generated by ⁹⁹mTc conjugated to intercalators are primarily caused by indirect effects through clustering.

  13. Effect Displays in R for Generalised Linear Models

    Directory of Open Access Journals (Sweden)

    John Fox

    2003-07-01

    Full Text Available This paper describes the implementation in R of a method for tabular or graphical display of terms in a complex generalised linear model. By complex, I mean a model that contains terms related by marginality or hierarchy, such as polynomial terms, or main effects and interactions. I call these tables or graphs effect displays. Effect displays are constructed by identifying high-order terms in a generalised linear model. Fitted values under the model are computed for each such term. The lower-order "relatives" of a high-order term (e.g., main effects marginal to an interaction are absorbed into the term, allowing the predictors appearing in the high-order term to range over their values. The values of other predictors are fixed at typical values: for example, a covariate could be fixed at its mean or median, a factor at its proportional distribution in the data, or to equal proportions in its several levels. Variations of effect displays are also described, including representation of terms higher-order to any appearing in the model.

  14. Renovating the Main Building

    CERN Multimedia

    CERN Bulletin

    2010-01-01

    CERN's "Main Building" is exactly that. The Organization's central hub, with hundreds of staff and visitors passing through its doors every day, will soon be getting a well-earned facelift. Refurbishment work will proceed in phases, starting with the Salle des Pas Perdus, the concourse between the Council Chamber and the Main Auditorium. By the end of August, informal seating areas will be installed, electronic display panels will provide practical information and improved sound insulation will enhance conditions in the auditoria and surrounding meeting rooms.   In light green the area that will undergo the facelift. Work will start in July. The ground floor is home to the entrance to Restaurant No. 1, the bank, the post office, the travel agent, the Users Office, the Staff Association, the notice boards etc. Step up to the first floor to access CERN's largest lecture theatre, the Council Chamber and its "Pas Perdus" lobby. Everyone who works at or visits CERN i...

  15. Fermilab Main Injector plan

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    1990-07-15

    The Fermilab Main Injector is the centrepiece of the 'Fermilab III' scheme to significantly upgrade the Laboratory's existing accelerator complex. The new accelerator is designed to provide increased particle beam levels to boost the collision rate in the Tevatron proton-antiproton collider (luminosity in excess of 5 x 10{sup 31} per sq cm per s) and, if approved, would provide increased flexibility in all areas of high energy physics research.

  16. Fermilab Main Injector plan

    International Nuclear Information System (INIS)

    Anon.

    1990-01-01

    The Fermilab Main Injector is the centrepiece of the 'Fermilab III' scheme to significantly upgrade the Laboratory's existing accelerator complex. The new accelerator is designed to provide increased particle beam levels to boost the collision rate in the Tevatron proton-antiproton collider (luminosity in excess of 5 x 10 31 per sq cm per s) and, if approved, would provide increased flexibility in all areas of high energy physics research

  17. Maine coast winds

    Energy Technology Data Exchange (ETDEWEB)

    Avery, Richard

    2000-01-28

    The Maine Coast Winds Project was proposed for four possible turbine locations. Significant progress has been made at the prime location, with a lease-power purchase contract for ten years for the installation of turbine equipment having been obtained. Most of the site planning and permitting have been completed. It is expect that the turbine will be installed in early May. The other three locations are less suitable for the project, and new locations are being considered.

  18. Project evaluation: main characteristics

    OpenAIRE

    Moutinho, Nuno

    2010-01-01

    — The evaluation process of real investment projects must consider not only the traditional financial approach, but also non-financial aspects. Non financial analysis can provide additional relevant information about projects. We investigate financial and non-financial areas most relevant in project appraisal. We present main critical success factors and areas of analysis that lead to the perception of project success. Finally, companies are segmented to verify its financial and non-financial...

  19. Marketing Maine Tablestock Potatoes

    OpenAIRE

    Berney, Gerald; Grajewski, Gregory; Hinman, Don; Prater, Marvin E.; Taylor, April

    2010-01-01

    The Marketing Services Division of USDA’s Agricultural Marketing Service (AMS) was asked by USDA’s Agricultural Research Service (ARS) National Program Leader and ARS’s New England Soil and Water Research Laboratory personnel to help with existing efforts to assist Maine fresh potato farmers in their search for alternative marketing strategies, and reverse the recent decline in the profitability of their operations. ARS researchers previously had conducted an exhaustive study defining possibl...

  20. Mapping distribution and thickness of supraglacial debris in the Central Karakoram National Park: main features and implications to model glacier meltwater

    Science.gov (United States)

    Minora, Umberto; Mayer, Christoph; Bocchiola, Daniele; D'Agata, Carlo; Maragno, Davide; Lambrecht, Astrid; Vuillermoz, Elisa; smiraglia, claudio; diolaiuti, guglielmina

    2014-05-01

    Supraglacial debris plays a not negligible role in controlling magnitude and rates of buried ice melt (Østrem, 1959; Mattson et al., 1993). Knowledge on rock debris is essential to model ice melt (and consequently meltwater discharge) upon wide glacierized areas, as melt rates are mainly driven by debris thickness variability. This is particularly important for the Pamir-Himalaya-Karakoram area (PHK), where debris-covered glaciers are frequent (Smiraglia et al., 2007; Scherler et al., 2011) and where melt water from glaciers supports agriculture and hydropower production. By means of remote sensing techniques and field data, supraglacial debris can be detected, and then quantified in area and thickness. Supervised classifications of satellite imagery can be used to map debris on glaciers. They use different algorithms to cluster an image based on its pixel values, and Region Of Interests (ROIs) previously selected by the human operator. This can be used to obtain a supraglacial debris mask by which surface extension can be calculated. Moreover, kinetic surface temperature data derived from satellites (such as ASTER and Landsat), can be used to quantify debris thicknesses (Mihalcea et al., 2008). Ground Control Points (GCPs) are essential to validate the obtained debris thicknesses. We took the Central Karakoram National Park (CKNP) as a representative sample for PHK area. The CKNP is 12,000 km2 wide, with more than 700 glaciers, mostly debris covered (Minora et al., 2013). Among those we find some of the widest glaciers of the World (e.g: Baltoro). To improve the knowledge on these glaciers and to better model their melt and water discharge we proceeded as follows. Firstly we ran a Supervised Maximum Likelihood (SML) classification on 2001 and 2010 Landsat images to detect debris presence and distribution. Secondly we analyzed kinetic surface temperature (from Landsat) to map debris depth. This latter attempt took also advantage from field data of debris thickness

  1. A Strategic Systems Model for Effective Recruiting

    National Research Council Canada - National Science Library

    Woolever, Daniel

    2003-01-01

    .... After introducing a model for effective and efficient recruiting, this Strategic Research Project describes the Air Force recruiting organizational structure, management processes and practices...

  2. Modeling of Pressure Effects in HVDC Cables

    DEFF Research Database (Denmark)

    Szabo, Peter; Hassager, Ole; Strøbech, Esben

    1999-01-01

    A model is developed for the prediction of pressure effects in HVDC mass impregnatedcables as a result of temperature changes.To test the model assumptions, experiments were performed in cable like geometries.It is concluded that the model may predict the formation of gas cavities.......A model is developed for the prediction of pressure effects in HVDC mass impregnatedcables as a result of temperature changes.To test the model assumptions, experiments were performed in cable like geometries.It is concluded that the model may predict the formation of gas cavities....

  3. The Effects of Modeling and Behavior Rehearsal in Assertive Training with Adolescents.

    Science.gov (United States)

    Parr, Gerald D.; Lundquist, Gerald

    The effects of modeling and rehearsal in counseling nonassertive adolescents were examined by randomly assigning subjects (Ss) to one of five treatment groups: modeling plus rehearsal (MR), modeling only (M), rehearsal only (R), placebo control (P), or delayed-treatment control (C). Significant (p < .05) main effects for treatment were found on…

  4. Residential Energy Efficiency Potential: Maine

    Energy Technology Data Exchange (ETDEWEB)

    Wilson, Eric J [National Renewable Energy Laboratory (NREL), Golden, CO (United States)

    2017-11-02

    Energy used by Maine single-family homes that can be saved through cost-effective improvements. Prepared by Eric Wilson and Noel Merket, NREL, and Erin Boyd, U.S. Department of Energy Office of Energy Policy and Systems Analysis.

  5. Modeling the effects of labeling

    DEFF Research Database (Denmark)

    Juhl, Hans Jørn; Fjord, Thomas Ahle; Poulsen, Carsten Stig

    A new approach to evaluate the consequences of labeling is presented and applied to test the potential effect of a label on fresh fish. Labeling effects on quality perceptions and overall quality are studied. The empirical study is based on an experimental design and nearly 500 respondents...

  6. Preventive effect of dipeptidyl peptidase-4 inhibitor on atherosclerosis is mainly attributable to incretin's actions in nondiabetic and diabetic apolipoprotein E-null mice.

    Directory of Open Access Journals (Sweden)

    Michishige Terasaki

    confers a substantial anti-atherosclerotic effect in both nondiabetic and diabetic mice, mainly via the action of the two incretins. However, the partial attenuation of atherosclerotic lesions by the dual incretin receptor antagonists in diabetic mice implies that vildagliptin confers a partial anti-atherogenic effect beyond that from the incretins.

  7. Effects of two main metabolites of sulphate-reducing bacteria on the corrosion of Q235 steels in 3.5 wt.% NaCl media

    International Nuclear Information System (INIS)

    Bao, Qi; Zhang, Dun; Lv, Dandan; Wang, Peng

    2012-01-01

    Highlights: ► Extracellular polymeric substances have been isolated from a batch culture of sulphate-reducing bacteria successfully. ► Sulphide and extracellular polymeric substances have triggered distinct electrochemical characteristics. ► ATR-IR analysis has confirmed the Fe 2+ -complexing capability of extracellular polymeric substances. ► In situ AFM results show extracellular polymeric substances can form a densely packed film on Q235 steels. ► The adsorbed extracellular polymeric substances film has protected the Q235 steels to a certain degree. - Abstract: The electrochemical corrosion behaviour of Q235 steels in 3.5 wt.% NaCl solutions with sulphide and extracellular polymeric substances (EPS), the two main metabolites of sulphate-reducing bacteria, was separately investigated through potentiodynamic polarisation and electrochemical impedance spectroscopy. Either sulphide or EPS increased the anodic current density by nearly one order of magnitude and negatively shifted the corrosion potential. The effects of EPS at the initial stage of corrosion may be ascribed to the Fe 2+ -complexing capability and the quickly adsorbed film. Moreover, the feeble protective effect of EPS after 16 d of immersion was observed through scanning electron microscopy.

  8. [Effect of NH4(+) -N/NO3(-)-N ratio in applied supplementary fertilizer on nitrogen metabolism and main chemical composition of Pinellia ternata].

    Science.gov (United States)

    Hu, Long-Jiao; Wang, Kang-Cai; Li, Can-Wen

    2013-07-01

    To study the effect of nitrogen forms on nitrogen metabolism and main chemical composition of Pinellia ternate. Through the soilless cultivation experiment and based at the same nitrogen level and different NH4(+) -N/NO3(-) -N ratios, nitrate reductase (NR) activity, glutamine synthetase (GS) activity, the content of nitrate nitrogen and ammonium nitrogen in different parts of P. ternate were determined. The contents of total alkaloid, free total organic acids and guanosine in the tuber were determined. The yield of bulbil and tuber was calculated. The test results showed that, with the NH4(+) -N/NO3(-) -N ratio increasing, the activity of nitrate reductase decreased, the content of nitrate nitrogen in the leaves, petioles and tuber increasing initially, then decreased, and the content of nitrate nitrogen in the root decreased. Meanwhile, with the NH4(+) -N/NO3(-) -N ratio increasing, the activity of glutamine synthetase in the leaves, petioles and root increased, the activity of glutamine synthetase in the tuber increasing initially, then decreased. The contents of ammonium nitrogen in the leaves, tuber and root increased initially, then decreased, and the contents of ammonium nitrogen in the petioles increased with the NH4(+)(-N/NO3(-)-N ratio increasing. The yield of bulbil and tuber were the highest at the NH4(+)-N/NO3(-) -N ratio of 75: 25. The content of total alkaloid and guanosine in the tuber were the highest at the NH4(+)-N/NO3(-) -N ratio of 0: 100, and the contents were 0.245% and 0.0197% respectively. With the NH4(+)-N/NO3(-) -N ratio of 50: 50, the content of free total organic acids was the highest, it reached 0.7%, however, the content of free total organic acids was the lowest at the NH4(+) -N/NO3(-) -N ratio of 0: 100. Nitrogen fertilization significant influences the nitrogen metabolism, the yield and main chemical composition of P. ternate.

  9. Using model analyses and surface-atmosphere exchange measurements from the Howland AmeriFlux Site in Maine, USA, to improve understanding of forest ecosystem C cycling

    Energy Technology Data Exchange (ETDEWEB)

    Hollinger, David Y.; Davidson, Eric A.; Richardson, Andrew D.; Dail, D. B.; Scott, N.

    2013-03-25

    Summary of research carried out under Interagency Agreement DE-AI02-07ER64355 with the USDA Forest Service at the Howland Forest AmeriFlux site in central Maine. Includes a list of publications resulting in part or whole from this support.

  10. Fire Health Main

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This model combines stand density index (SDI), basal area loss, drought stress, and insect and disease surveys using an equal weight overlay. SDI determines the...

  11. Summary of main points

    International Nuclear Information System (INIS)

    2006-01-01

    In conjunction with its 6. annual meeting, the WPDD in close co-operation with the FSC held a Topical session on 'Stakeholder Involvement in Decommissioning' on November 14, 2005. The session was attended by 36 participants totally representing 14 NEA member countries and 2 international organisations. Two keynote addresses were given at the Topical Session. The first one treated of what is needed for robust decisions and how to bring all stakeholders into the debate. In the second keynote address a summary was made on what have been said on stakeholder involvement in decommissioning during earlier meetings of the WPDD. The main part of the session was then devoted to views from different stakeholders regarding their role and their involvement. This part contained viewpoints from local communities (Kaevlinge in Sweden and Port Hope in Canada), authorities (Scottish Executive and CSNC) and operators (EDF from France and EWN from Germany). Case studies from the decommissioning of Dounrey in the UK and from Trojan and Main Yankee in the USA were presented in the end part of the Topical session followed by a summary and lessons learnt report by the Rapporteur. A detailed programme of the Topical session can be seen in Appendix 1

  12. Effects of clary sage oil and its main components, linalool and linalyl acetate, on the plasma membrane of Candida albicans: an in vivo EPR study.

    Science.gov (United States)

    Blaskó, Ágnes; Gazdag, Zoltán; Gróf, Pál; Máté, Gábor; Sárosi, Szilvia; Krisch, Judit; Vágvölgyi, Csaba; Makszin, Lilla; Pesti, Miklós

    2017-02-01

    The effects of clary sage (Salvia sclarea L.) oil (CS-oil), and its two main components, linalool (Lol) and linalyl acetate (LA), on cells of the eukaryotic human pathogen yeast Candida albicans were studied. Dynamic and thermodynamic properties of the plasma membrane were investigated by electron paramagnetic resonance (EPR) spectroscopy, with 5-doxylstearic acid (5-SASL) and 16-SASL as spin labels. The monitoring of the head group regions with 5-SASL revealed break-point frequency decrease in a temperature dependent manner of the plasma membrane between 9.55 and 13.15 °C in untreated, in CS-oil-, Lol- and LA-treated membranes. The results suggest a significant increase in fluidity of the treated plasma membranes close to the head groups. Comparison of the results observed with the two spin labels demonstrated that CS-oil and LA induced an increased level of fluidization at both depths of the plasma membrane. Whereas Lol treatment induced a less (1 %) ordered bilayer organization in the superficial regions and an increased (10 %) order of the membrane leaflet in deeper layers. Acute toxicity tests and EPR results indicated that both the apoptotic and the effects exerted on the plasma membrane fluidity depended on the composition and chemical structure of the examined materials. In comparison with the control, treatment with CS-oil, Lol or LA induced 13.0, 12.3 and 26.4 % loss respectively, of the metabolites absorbing at 260 nm, as a biological consequence of the plasma membrane fluidizing effects. Our results confirmed that clary sage oil causes plasma membrane perturbations which leads to cell apoptosis process.

  13. Temporal evolution of ultrafine particles and of alveolar deposited surface area from main indoor combustion and non-combustion sources in a model room.

    Science.gov (United States)

    Manigrasso, Maurizio; Vitali, Matteo; Protano, Carmela; Avino, Pasquale

    2017-11-15

    Aerosol number size distributions, PM mass concentrations, alveolar deposited surface areas (ADSAs) and VOC concentrations were measured in a model room when aerosol was emitted by sources frequently encountered in indoor environments. Both combustion and non-combustion sources were considered. The most intense aerosol emission occurred when combustion sources were active (as high as 4.1×10 7 particlescm -3 for two meat grilling sessions; the first with exhaust ventilation, the second without). An intense spike generation of nucleation particles occurred when appliances equipped with brush electric motors were operating (as high as 10 6 particlescm -3 on switching on an electric drill). Average UFP increments over the background value were highest for electric appliances (5-12%) and lowest for combustion sources (as low as -24% for tobacco cigarette smoke). In contrast, average increments in ADSA were highest for combustion sources (as high as 3.2×10 3 μm 2 cm -3 for meat grilling without exhaust ventilation) and lowest for electric appliances (20-90μm 2 cm -3 ). The health relevance of such particles is associated to their ability to penetrate cellular structures and elicit inflammatory effects mediated through oxidative stress in a way dependent on their surface area. The highest VOC concentrations were measured (PID probe) for cigarette smoke (8ppm) and spray air freshener (10ppm). The highest PM mass concentration (PM 1 ) was measured for citronella candle burning (as high as 7.6mgm -3 ). Copyright © 2017 Elsevier B.V. All rights reserved.

  14. TRIGA reactor main systems

    International Nuclear Information System (INIS)

    Boeck, H.; Villa, M.

    2007-01-01

    This module describes the main systems of low power (<2 MW) and higher power (≥2 MW) TRIGA reactors. The most significant difference between the two is that forced reactor cooling and an emergency core cooling system are generally required for the higher power TRIGA reactors. However, those TRIGA reactors that are designed to be operated above 3 MW also use a TRIGA fuel that is specifically designed for those higher power outputs (3 to 14 MW). Typical values are given for the respective systems although each TRIGA facility will have unique characteristics that may only be determined by the experienced facility operators. Due to the inherent wide scope of these research reactor facilities construction and missions, this training module covers those systems found at most operating TRIGA reactor facilities but may also discuss non-standard equipment that was found to be operationally useful although not necessarily required. (author)

  15. ReliefSeq: a gene-wise adaptive-K nearest-neighbor feature selection tool for finding gene-gene interactions and main effects in mRNA-Seq gene expression data.

    Directory of Open Access Journals (Sweden)

    Brett A McKinney

    Full Text Available Relief-F is a nonparametric, nearest-neighbor machine learning method that has been successfully used to identify relevant variables that may interact in complex multivariate models to explain phenotypic variation. While several tools have been developed for assessing differential expression in sequence-based transcriptomics, the detection of statistical interactions between transcripts has received less attention in the area of RNA-seq analysis. We describe a new extension and assessment of Relief-F for feature selection in RNA-seq data. The ReliefSeq implementation adapts the number of nearest neighbors (k for each gene to optimize the Relief-F test statistics (importance scores for finding both main effects and interactions. We compare this gene-wise adaptive-k (gwak Relief-F method with standard RNA-seq feature selection tools, such as DESeq and edgeR, and with the popular machine learning method Random Forests. We demonstrate performance on a panel of simulated data that have a range of distributional properties reflected in real mRNA-seq data including multiple transcripts with varying sizes of main effects and interaction effects. For simulated main effects, gwak-Relief-F feature selection performs comparably to standard tools DESeq and edgeR for ranking relevant transcripts. For gene-gene interactions, gwak-Relief-F outperforms all comparison methods at ranking relevant genes in all but the highest fold change/highest signal situations where it performs similarly. The gwak-Relief-F algorithm outperforms Random Forests for detecting relevant genes in all simulation experiments. In addition, Relief-F is comparable to the other methods based on computational time. We also apply ReliefSeq to an RNA-Seq study of smallpox vaccine to identify gene expression changes between vaccinia virus-stimulated and unstimulated samples. ReliefSeq is an attractive tool for inclusion in the suite of tools used for analysis of mRNA-Seq data; it has power to

  16. Effective potential models for hadrons

    International Nuclear Information System (INIS)

    Lucha, W.

    1995-12-01

    The aim of these lectures is to give a self-contained introduction to nonrelativistic potential models, to their formulation as well as to their possible applications. At the price of some lack of (in a mathematical sense) rigorous derivations, we try to give a feeling and understanding for the simplest conceivable method to extract the explicit form of the forces acting between quarks from the interplay between experimental observations and theoretical considerations. According to this spirit, we demonstrate, in detail, how to obtain the underlying Hamiltonian and how to determine the Lorentz structure of the quark-(anti-)quark interaction potential from well-established experimental facts. (author)

  17. Investigation of the effect of tribulus terrestris extract on the main biochemical and haematological indices of the blood in guinea fowls (Numida meleagris

    Directory of Open Access Journals (Sweden)

    Christo CHRISTEV

    2011-07-01

    Full Text Available The aim of the present research was to investigate the effect of Bulgarian additive Vemoherb-T (dry extract of the annual plant Tribulus terrestris – L, produced by Vemo 99 Ltd Company, Sofia on main biochemical characteristics and hematological parameters of the blood in guinea fowl (Numida meleagris. An experiment was carried out with 30 Pearl-gray Guinea fowl (32 weeks old, distributed in two groups – a control and an experimental, 12 female and 3 male each. All birds were fed the same mixture for breeder guinea fowl. Vemoherb-T was supplemented to the compound feed of the experimental group in a daily dose of 10 mg/kg body weight for a period of 12 weeks. The tested product decreased significantly the levels of total triglycerides (P < 0.05, total cholesterol (P <0.01 and glucose (P < 0.01; P < 0.001 in male and female birds respectively in the blood serum. It was established significantly higher total protein- ((P < 0.001 and calcium (P<0.01 values in the blood serum of the treated birds. The addition of Vemoherb-T increased significantly hemoglobin level, the number of erythrocytes and leukocytes and decreased the number of eosinophils in guinea fowl from the both sexes.

  18. Characterization of a clock based on coherent population trapping in a thermal cesium vapor. Main effects that may affect its mid- and long-term frequency stability

    International Nuclear Information System (INIS)

    Kozlova, Olga

    2013-01-01

    This thesis describes a Cs - buffer gas vapor cell atomic clock based on coherent population trapping (CPT), and the main frequency shifts affecting its mid- and long-term stability. The developed atomic clock based on CPT uses two original techniques: a so-called double-Λ scheme for the CPT-resonance excitation and a temporal Ramsey interrogation technique, which produce a high contrast and narrow resonances with reduced light shift dependence. Generally, the mid and long term stability of the vapor cell atomic clock is limited by the collisional shift induced by alkali-buffer gas collisions and the light shift (or the effects depending on the laser intensity). We report on the study of the collisional shift of Cs clock frequency in the presence of Ne, N 2 or Ar buffer gas, and its temperature dependence. The coefficient values of this dependence for these three buffer gases were revealed (some of them for the first time), allowing us to realise a cell with optimal combination of buffer gases to cancel the temperature dependence around the working temperature. Following the study of the signal amplitude and the coherence relaxation rate the optimal values for such parameters as interrogation cycle, magnetic field, cell temperature, pressure of the buffer gas mixture, etc. were found for the chosen cell. The investigation on the light shift and the effects depending on the laser intensity allowed us to determine the most sensitive parameters (laser intensity ratio, temperature) and to implement the required stabilizations in order to better control them. Finally, the mid- and long-term clock frequency stability was improved by a factor 40, reaching 2.5 10 -14 at 1 hour. (author)

  19. Standard Model Effective Potential from Trace Anomalies

    Directory of Open Access Journals (Sweden)

    Renata Jora

    2018-01-01

    Full Text Available By analogy with the low energy QCD effective linear sigma model, we construct a standard model effective potential based entirely on the requirement that the tree level and quantum level trace anomalies must be satisfied. We discuss a particular realization of this potential in connection with the Higgs boson mass and Higgs boson effective couplings to two photons and two gluons. We find that this kind of potential may describe well the known phenomenology of the Higgs boson.

  20. Modelling of Size Effect with Regularised Continua

    Directory of Open Access Journals (Sweden)

    H. Askes

    2004-01-01

    Full Text Available A nonlocal damage continuum and a viscoplastic damage continuum are used to model size effects. Three-point bending specimens are analysed, whereby a distinction is made between unnotched specimens, specimens with a constant notch and specimens with a proportionally scaled notch. Numerical finite element simulations have been performed for specimen sizes in a range of 1:64. Size effects are established in terms of nominal strength and compared to existing size effect models from the literature. 

  1. Chemical composition of Galla chinensis extract and the effect of its main component(s) on the prevention of enamel demineralization in vitro

    NARCIS (Netherlands)

    Huang, X.L.; Liu, M.D.; Li, J.Y.; Zhou, X.D.; ten Cate, J.M.

    2012-01-01

    To determine the chemical composition of Galla chinensis extract (GCE) by several analysis techniques and to compare the efficacy of GCE and its main component(s) in inhibition of enamel demineralization, for the development of future anticaries agents, main organic composition of GCE was

  2. Neuroprotective Properties of the Standardized Extract from Camellia sinensis (Green Tea and Its Main Bioactive Components, Epicatechin and Epigallocatechin Gallate, in the 6-OHDA Model of Parkinson’s Disease

    Directory of Open Access Journals (Sweden)

    Natália Bitu Pinto

    2015-01-01

    Full Text Available Camellia sinensis (green tea is largely consumed, mainly in Asia. It possesses several biological effects such as antioxidant and anti-inflammatory properties. The objectives were to investigate the neuroprotective actions of the standardized extract (CS, epicatechin (EC and epigallocatechin gallate (EGCG, on a model of Parkinson’s disease. Male Wistar rats were divided into SO (sham-operated controls, untreated 6-OHDA-lesioned and 6-OHDA-lesioned treated for 2 weeks with CS (25, 50, or 100 mg/kg, EC (10 mg/kg, or EGCG (10 mg/kg groups. One hour after the last administration, animals were submitted to behavioral tests and euthanized and their striata and hippocampi were dissected for neurochemical (DA, DOPAC, and HVA and antioxidant activity determinations, as well as immunohistochemistry evaluations (TH, COX-2, and iNOS. The results showed that CS and catechins reverted behavioral changes, indicating neuroprotection manifested as decreased rotational behavior, increased locomotor activity, antidepressive effects, and improvement of cognitive dysfunction, as compared to the untreated 6-OHDA-lesioned group. Besides, CS, EP, and EGCG reversed the striatal oxidative stress and immunohistochemistry alterations. These results show that the neuroprotective effects of CS and its catechins are probably and in great part due to its powerful antioxidant and anti-inflammatory properties, pointing out their potential for the prevention and treatment of PD.

  3. The effects of a local moderate tsunami in the Dover Strait on the French and English main harbors of the English Channel

    Science.gov (United States)

    Clément, Cécile; Gailler, Audrey; Heinrich, Philippe; Hélène, Hébert; Loevenbruck, Anne

    2017-04-01

    The Dover Strait is regularly shaken by small to moderate earthquakes which can be felt in the nearby cities Boulogne-Sur-Mer, Calais, Dover and Folkestone. Three destructive events have been documented during the Middle Ages including 1580 Dover Strait earthquake which has been largely felt in London. The isoseimal map of this main event shows a maximum MSK paleointensity of VIII in Calais and VII in Dover [Neilson et al 1984; Melville et al. 1996]. The Dover Strait has been studied using seismic-reflection method [Garcia-Moreno et al. 2014], seafloor sampling, boreholes and gravity anomaly [Everaerts and Mansy 2001], yet the actual tectonic context of the area stays hard to understand because of the lack of recent seafloor deformation and of large recent seismic events. Among other things the occurrence of a tsunamigenic earthquake is not totally impossible [Roger and Gunnell 2011]. We propose several numerical simulations of tsunamis where the seismic scenari are chosen according to the latest fault activity study of the area [Garcia-Moreno et al. 2014]. We used strike-slip and normal mechanisms for magnitudes ranging from 6.0 to 7.0. The propagation of the tsunamis from the source to the French an English coasts is made using a bathymetry with a grid step of 20m realized by the SHOM (Service Hydrographique et Océanographique de la Marine) within the TANDEM project. Using synthetic gauges, we measure the water elevation prediction at the entrance of the main harbours. We push the investigation further for the case of Boulogne-Sur-Mer where the available topography-bathymetry map has a grid step of 10m. This fine bathymetry map enables to modelize the bassins and the embankments inside the harbor and thus to study the resonance of the site. Moreover Boulogne harbor is equipped with a maregraph that we use to compare the synthetic data with real water height registration. Using maregraph recording of rough sea or storm, we are able to evaluate the relevance of

  4. Effects of social intervention on detection and efficacy of treatment for arterial hypertension. Main results of the Polish Four Cities Programme.

    Science.gov (United States)

    Zdrojewski, Tomasz; Głuszek, Jerzy; Posadzy-Małaczyńska, Anna; Drygas, Wojciech; Ornoch-Tabedzka, Małgorzata; Januszko, Wiktor; Tykarski, Andrzej; Dylewicz, Piotr; Kwaśniewska, Magdalena; Krupa-Wojciechowska, Barbara; Wyrzykowski, Bogdan

    2004-12-01

    Cardiovascular diseases are the main cause of death in the adult Polish population. Beside lipid disorders and cigarette smoking, hypertension represents the most important risk factor leading to cardiovascular complications. Representative studies conducted in Poland in 1994-2002 showed that in 2002 the number of respondents in the survey who stated they knew their own blood pressure values dropped by 3.5 million, compared with 1994. This decrease was predominantly seen in small towns and in the countryside. Preventive programmes should therefore be addressed mainly to the most vulnerable communities. Modern methods of social marketing may play a substantial role in the creation of a healthy lifestyle. The aim of the Polish Four Cities Programme (PP4M), conducted in 2000-2001, was to develop the most effective methods of detection of and improvement in treatment for hypertension among the residents of small towns and rural areas. One of the programme tasks was to compare the effectiveness of a standard medical screening intervention with a similar approach combined with the use of social marketing methods.Methods. The programme was conducted by an interdisciplinary team in three small Polish towns -- Kartuzy, Oborniki Wlkp. and Braniewo, as well as in one of the districts of a large city Łódź -- Olechów. Medical intervention combined with social marketing (community intervention) took place in Oborniki Wlkp. whereas the residents of Kartuzy and Łódź were subjected only to the traditional medical intervention. Braniewo served as a control location -- neither medical nor community intervention was implemented. Community intervention with elements of social marketing consisted of a three-month, intensive education and information campaign, initiated four weeks prior to the start of medical intervention. Epidemiological situation was assessed in all the four cities before and after the completion of the preventive interventions (screening), using representative

  5. Optimal Portfolios in Wishart Models and Effects of Discrete Rebalancing on Portfolio Distribution and Strategy Selection

    OpenAIRE

    Li, Zejing

    2012-01-01

    This dissertation is mainly devoted to the research of two problems - the continuous-time portfolio optimization in different Wishart models and the effects of discrete rebalancing on portfolio wealth distribution and optimal portfolio strategy.

  6. Timing and mechanisms for the deposition of the glaciomarine mud in and around the Gulf of Maine: A discussion of alternative models

    Science.gov (United States)

    Oldale, Robert N.

    1989-01-01

    Glaciomarine mud in the Gulf of Maine, characterized by rhythmic seismic layers that mimic the morphology of the underlying surface, is composed of subequal amounts of silt and clay, variable amounts of sand, and sparse gravel-sized clasts. The mud is Wisconsinan in age and was deposited during the retreat of the last ice sheet. A beginning date of 38 ka, proposed by King and Fader (1986) in their chronology of the last deglaciation, is considered too old. An alternative chronology, more consistent with the continental record to the west, is proposed here. ln this interpretation, deposition ofglaciomarine mud began about 18 ka when the late Wisconsinan ice retreated from Georges Bank, Great South Channel, and Northeast Channel and ended around 11 ka, when meltwater ceased to enter the Gulf of Maine. Basal-till melt-out from an ice shelf and bergs as the source of the glaciomarine mud, also proposed by King and Fader (1986), is thought to be inconsistent with the volume, widespread rhythmic bedding, and low stone content of the deposit. More likely the source of the glaciomarine mud was rock-flour-laden meltwater that entered the sea along the grounding line of a calving glacier or by way of subaerial meltwater streams. The rock flour was then dispersed by sediment plumes and was deposited when the sediment fell to the sea floor, aided by flocculation and biological agglutination. Rhythmic layers within the glaciomarine mud could represent annual cyclic sedimentation (varves) or cyclic events of lesser duration.

  7. The opposition effect in Saturn's main rings as seen by Cassini ISS: 4. Correlations of the surge morphology with surface albedos and VIMS spectral properties

    Science.gov (United States)

    Déau, Estelle; Dones, Luke; Mishchenko, Michael I.; West, Robert A.; Helfenstein, Paul; Hedman, Matt M.; Porco, Carolyn C.

    2018-05-01

    In this paper, we continue our analysis of the saturnian ring opposition effect seen by Cassini ISS. The ring opposition effect is a peak in the rings' reflectivity caused as the directions from a spot on the rings to the observer and to the light source, respectively, converge toward zero degrees. So far, the exact origin of the ring's opposition effect is still a matter of debate. In our previous work (Déau, et al., 2013, Icarus, 226, 591-603), we compared the opposition effect morphology with the rings' optical depth and found that only the slope of the linear part of the rings' phase curves was strongly correlated with the optical depth. We interpreted this as an indication of the predominant role of interparticle shadowing at moderate phase angles (α ∼ 10-40o). More recently (Déau, 2015, Icarus, 253, 311-345), we showed that interparticle shadowing cannot explain the behavior at low phase angles (α Journal Letters, 711, L71-L74). We find that the opposition surge morphology is strongly correlated with the water ice band depth and the regolith albedo. We interpret this finding as an indication that coherent backscattering plays a role in affecting both the water ice band depths and the opposition surge at low phase angles (α < 1o). As the regolith albedo and spectral properties are related to the grain size, porosity, roughness, and composition, we try to assess which of these regolith properties are preponderant in coherent backscattering. Our study is able to narrow down the parameter space of these properties, whose values allow a good match between the angular width predicted by models of coherent backscattering and the width of the observed peak.

  8. Investigation of the Effect of Rice Wine on the Metabolites of the Main Components of Herbal Medicine in Rat Urine by Ultrahigh-Performance Liquid Chromatography-Quadrupole/Time-of-Flight Mass Spectrometry: A Case Study on Cornus officinalis

    Directory of Open Access Journals (Sweden)

    Gang Cao

    2013-01-01

    Full Text Available Ultrahigh-performance liquid chromatography-quadrupole/time-of-flight mass spectrometry (UPLC-QTOF/MS was developed for rapid and sensitive analysis of the effect of rice wine on the metabolites of the main components of herbal medicine in rat urine. Using Cornus officinalis as a model of herbal medicine, the metabolite profiles of crude and processed (steaming the crude drug presteeped in rice wine Cornus officinalis extracts in rat urine were investigated. The metabolites of Cornus officinalis were identified by using dynamic adjustment of the fragmentor voltage to produce structure-relevant fragment ions. In this work, we identified the parent compounds and metabolites of crude and processed Cornus officinalis in rats. In total, three parent compounds and seventeen new metabolites of Cornus officinalis were found in rats. The contents of the parent compounds and metabolites in vivo varied significantly after intragastric (i.g. administration of aqueous extracts of crude and processed Cornus officinalis. Data from this study suggests that UPLC-QTOF/MS could be used as a potential tool for uncovering the effects of excipients found in the metabolites of the main components of herbal medicine, in vivo, to predict and discover the processing mechanisms of herbal medicine.

  9. EFFECT OF METALLICITY ON THE EVOLUTION OF THE HABITABLE ZONE FROM THE PRE-MAIN SEQUENCE TO THE ASYMPTOTIC GIANT BRANCH AND THE SEARCH FOR LIFE

    Energy Technology Data Exchange (ETDEWEB)

    Danchi, William C. [Exoplanets and Stellar Astrophysics Laboratory, NASA Goddard Space Flight Center, Code 667, Greenbelt, MD 20771 (United States); Lopez, Bruno, E-mail: william.c.danchi@nasa.gov, E-mail: bruno.lopez@oca.eu [Observatoire de la Cote d' Azur, Laboratoire Lagrange UMR 7293, BP 4229, F-06034 Nice Cedex 4 (France)

    2013-05-20

    During the course of stellar evolution, the location and width of the habitable zone changes as the luminosity and radius of the star evolves. The duration of habitability for a planet located at a given distance from a star is greatly affected by the characteristics of the host star. A quantification of these effects can be used observationally in the search for life around nearby stars. The longer the duration of habitability, the more likely it is that life has evolved. The preparation of observational techniques aimed at detecting life would benefit from the scientific requirements deduced from the evolution of the habitable zone. We present a study of the evolution of the habitable zone around stars of 1.0, 1.5, and 2.0 M{sub Sun} for metallicities ranging from Z = 0.0001 to Z = 0.070. We also consider the evolution of the habitable zone from the pre-main sequence until the asymptotic giant branch is reached. We find that metallicity strongly affects the duration of the habitable zone for a planet as well as the distance from the host star where the duration is maximized. For a 1.0 M{sub Sun} star with near solar metallicity, Z = 0.017, the duration of the habitable zone is >10 Gyr at distances 1.2-2.0 AU from the star, whereas the duration is >20 Gyr for high-metallicity stars (Z = 0.070) at distances of 0.7-1.8 AU, and {approx}4 Gyr at distances of 1.8-3.3 AU for low-metallicity stars (Z = 0.0001). Corresponding results have been obtained for stars of 1.5 and 2.0 solar masses.

  10. Main and interactive effects of emotion dysregulation and HIV symptom severity on quality of life among persons living with HIV/AIDS.

    Science.gov (United States)

    Brandt, Charles P; Jardin, Charles; Sharp, Carla; Lemaire, Chad; Zvolensky, Michael J

    2017-04-01

    HIV symptoms are associated with a poorer quality of life (QOL) among persons living with HIV/AIDS (PLWHA). Yet, there is little understanding of emotional factors that impact the relation between HIV symptom severity and QOL. The present study examined the main and interactive effects of emotion dysregulation and HIV symptom severity on multiple indices of QOL, including physical (impact of physical problems related to HIV), psychological (frequency of negative feelings), independence (necessity of medical treatment to function in daily life), social (feelings of acceptance), environmental (satisfaction with living conditions and medical care), and spiritual (fear of the future and death) among a sample of 74 PLWHA. Participants (72.9% male; mean age = 48.24, SD = 7.85) were recruited from AIDS Service Organizations in the United States. Results indicated that higher HIV symptom severity is significantly associated with lower physical and independence QOL, whereas higher emotion dysregulation is significantly associated with lower scores on all measured aspects of QOL. Additionally, results indicated that the interaction of emotion dysregulation and HIV symptom severity was significantly associated with both physical and environmental QOL. The form of the observed significant interactions indicated that HIV symptom severity was related to poorer QOL among those with lower (versus higher) emotion dysregulation. The present findings indicate that emotion dysregulation is related to QOL among PLWHA and may interact with HIV symptom severity to negatively impact certain aspects of QOL. Given the profound impact that HIV has on QOL, this finding is important in understanding these relations mechanistically, and may be important in the development of novel psychological treatment strategies.

  11. EFFECT OF METALLICITY ON THE EVOLUTION OF THE HABITABLE ZONE FROM THE PRE-MAIN SEQUENCE TO THE ASYMPTOTIC GIANT BRANCH AND THE SEARCH FOR LIFE

    International Nuclear Information System (INIS)

    Danchi, William C.; Lopez, Bruno

    2013-01-01

    During the course of stellar evolution, the location and width of the habitable zone changes as the luminosity and radius of the star evolves. The duration of habitability for a planet located at a given distance from a star is greatly affected by the characteristics of the host star. A quantification of these effects can be used observationally in the search for life around nearby stars. The longer the duration of habitability, the more likely it is that life has evolved. The preparation of observational techniques aimed at detecting life would benefit from the scientific requirements deduced from the evolution of the habitable zone. We present a study of the evolution of the habitable zone around stars of 1.0, 1.5, and 2.0 M ☉ for metallicities ranging from Z = 0.0001 to Z = 0.070. We also consider the evolution of the habitable zone from the pre-main sequence until the asymptotic giant branch is reached. We find that metallicity strongly affects the duration of the habitable zone for a planet as well as the distance from the host star where the duration is maximized. For a 1.0 M ☉ star with near solar metallicity, Z = 0.017, the duration of the habitable zone is >10 Gyr at distances 1.2-2.0 AU from the star, whereas the duration is >20 Gyr for high-metallicity stars (Z = 0.070) at distances of 0.7-1.8 AU, and ∼4 Gyr at distances of 1.8-3.3 AU for low-metallicity stars (Z = 0.0001). Corresponding results have been obtained for stars of 1.5 and 2.0 solar masses.

  12. Scientists' internal models of the greenhouse effect

    Science.gov (United States)

    Libarkin, J. C.; Miller, H.; Thomas, S. R.

    2013-12-01

    A prior study utilized exploratory factor analysis to identify models underlying drawings of the greenhouse effect made by entering university freshmen. This analysis identified four archetype models of the greenhouse effect that appear within the college enrolling population. The current study collected drawings made by 144 geoscientists, from undergraduate geoscience majors through professionals. These participants scored highly on a standardized assessment of climate change understanding and expressed confidence in their understanding; many also indicated that they teach climate change in their courses. Although geoscientists held slightly more sophisticated greenhouse effect models than entering freshmen, very few held complete, explanatory models. As with freshmen, many scientists (44%) depict greenhouse gases in a layer in the atmosphere; 52% of participants depicted this or another layer as a physical barrier to escaping energy. In addition, 32% of participants indicated that incoming light from the Sun remains unchanged at Earth's surface, in alignment with a common model held by students. Finally, 3-20% of scientists depicted physical greenhouses, ozone, or holes in the atmosphere, all of which correspond to non-explanatory models commonly seen within students and represented in popular literature. For many scientists, incomplete models of the greenhouse effect are clearly enough to allow for reasoning about climate change. These data suggest that: 1) better representations about interdisciplinary concepts, such as the greenhouse effect, are needed for both scientist and public understanding; and 2) the scientific community needs to carefully consider how much understanding of a model is needed before necessary reasoning can occur.

  13. Cooked meat products made of coarsely ground pork: the main bacterial strains of bacterial flora, their heat resistance and effect on spoilage

    Directory of Open Access Journals (Sweden)

    Esko Petäjä

    1993-09-01

    Full Text Available This study was conducted to investigate the bacterial flora of the surface layer and the core of meat products made of coarsely ground pork at the moment of spoilage when stored at 7°C or 4°C. The dominating strains were isolated, their heat resistance was studied in APT-broth, on APT-agar and in coarsely ground cured pork, and their growth after heating and effect on spoilage were followed in coarsely ground cured pork. The first signs of spoilage appeared in the surface layer of the products. The strains were coccoid lactic acid bacteria with counts ranging from 3,5 to 7.8 log cfu (colony forming units/g. They survived only accidentally after heating for 15 minutes at 72°C in APT-broth. The core of the products contained only coccoid lactic acid bacteria or only pseudomonads or both as the main bacterial strains. The counts ranged from 2.6 to 6.0 log cfu/g. Most of the strains isolated from the core survived after heating for 30 minutes at 72°C in APT-broth in at least three tests out of six. The most noticeable result of the study was the occurence of heat-resistant pseudomonads in the core. It must be pointed out that all pseudomonads found survived after heating for 60 minutes at 72°C in APT-broth, and often after heating for 15 minutes at 72°C in coarsely ground cured pork (core 72°C. The cfu number of the two most heat-resistant streptococcus strains decreased only 1 log unit over 15 minutes at 72°C in coarsely ground cured pork. The numbers of inoculated pseudomonads decreased but those of streptococci rose by a maximum of 1 log unit when the experimental porks were kept at 4°C after heating. This indicates that streptococci and pseudomonads probably do not constitute a serious spoilage factor in cooked meat products, but spoilage is generally effected by bacteria which have contaminated the surface layer of the products after heat treatment.

  14. Modelling the response of yields and tissue C : N to changes in atmospheric CO2 and N management in the main wheat regions of western Europe

    DEFF Research Database (Denmark)

    Olin, S.; Schurgers, Guy; Lindeskog, M.

    2015-01-01

    increase the model performance compared to an earlier version of the model that does not account for these interactions. For these simulations, we also demonstrate an implementation of N fertilisation timing for areas where this information is not available. This feature is crucial when accounting...... (DVMs) aim to accurately represent both natural vegetation and managed land, not only from a carbon cycle perspective but increasingly so also for a wider range of processes including crop yields. We present here the extended version of the DVM LPJ-GUESS that accounts for N limitation in crops...... production, tissue C to N ratios (C: N) and phenology. To test the model’s applicability for larger regions, simulations are subsequently performed that cover the wheatdominated regions of western Europe. When compared to regional yield statistics, the inclusion of C–N dynamics in the model substantially...

  15. Large breast size as a risk factor for late adverse effects of breast radiotherapy: Is residual dose inhomogeneity, despite 3D treatment planning and delivery, the main explanation?

    International Nuclear Information System (INIS)

    Goldsmith, Christy; Haviland, Joanne; Tsang, Yat; Sydenham, Mark; Yarnold, John

    2011-01-01

    Background and Purpose: Large breast size is associated with an increased risk of late adverse effects after breast conservation surgery and radiotherapy, even when 3D dosimetry is used. The purpose of this study is to test the hypothesis that residual dose inhomogeneity is sufficient to explain the association. Methods: Patients previously treated after breast conservation surgery with whole breast radiotherapy using 3D dosimetry and followed up in the UK FAST hypofractionation trial were selected for this analysis. The residual level of dose inhomogeneity across the whole breast treatment volume was used to test for association between residual dosimetry and post-treatment change in breast appearance at 2 years post-radiotherapy. Results: At 2 years, 201/279 (72%) of women had no change in photographic breast appearance, 61 (22%) had mild change and 17 (6%) had marked change. Breast size and dosimetry were both significantly associated with late effects in univariate analyses, but only breast size remained an independent significant risk factor for change in breast appearance when included in a multiple regression model together with other prognostic factors (p = 0.006 for trend). Conclusion: Large-breasted women are more likely to suffer change in breast size and shape after whole breast radiotherapy delivered using 3D dosimetry, but residual dose inhomogeneity is insufficient to explain the association.

  16. Decomposition of radiational effects of model feedbacks

    International Nuclear Information System (INIS)

    Ellsaesser, H.W.; MacCracken, M.C.; Potter, G.L.; Mitchell, C.S.

    1981-08-01

    Three separate doubled CO 2 experiments with the statistical dynamic model are used to illustrate efforts to study the climate dynamics, feedbacks, and interrelationships of meteorological parameters by decomposing and isolating their individual effects on radiation transport

  17. Suppression of inflammatory reactions by terpinen-4-ol, a main constituent of tea tree oil, in a murine model of oral candidiasis and its suppressive activity to cytokine production of macrophages in vitro.

    Science.gov (United States)

    Ninomiya, Kentaro; Hayama, Kazumi; Ishijima, Sanae A; Maruyama, Naho; Irie, Hiroshi; Kurihara, Junichi; Abe, Shigeru

    2013-01-01

    The onset of oral candidiasis is accompanied by inflammatory symptoms such as pain in the tongue, edema or tissue damage and lowers the quality of life (QOL) of the patient. In a murine oral candidiasis model, the effects were studied of terpinen-4-ol (T-4-ol), one of the main constituents of tea tree oil, Melaleuca alternifolia, on inflammatory reactions. When immunosuppressed mice were orally infected with Candida albicans, their tongues showed inflammatory symptoms within 24 h after the infection, which was monitored by an increase of myeloperoxidase activity and macrophage inflammatory protein-2 in their tongue homogenates. Oral treatment with 50 µL of 40 mg/mL terpinen-4-ol 3h after the Candida infection clearly suppressed the increase of these inflammatory parameters. In vitro analysis of the effects of terpinen-4-ol on cytokine secretion of macrophages indicated that 800 µg/mL of this substance significantly inhibited the cytokine production of the macrophages cultured in the presence of heat-killed C. albicans cells. Based on these findings, the role of the anti-inflammatory action of T-4-ol in its therapeutic activity against oral candidiasis was discussed.

  18. Intergenerational modelling of the greenhouse effect

    OpenAIRE

    Spash, Clive L.

    1994-01-01

    A major implication of global climate change is that future generations will suffer severe damages while the current generation benefits. In this paper a model is developed to analyze the potential need for mitigating the adverse impacts of the greenhouse effect on efficiency grounds. The model characterises basic transfers, investigate the effect of greenhouse emissions, and analyze exogenous and endogenous uncertainty. The first (or current) generation faces the problem of dividing availabl...

  19. Effective operator treatment of the Lipkin model

    International Nuclear Information System (INIS)

    Abraham, K.J.; Vary, J.P.

    2004-01-01

    We analyze the Lipkin model in the strong coupling limit using effective operator techniques. We present both analytical and numerical results for low energy effective Hamiltonians. We investigate the reliability of various approximations used to simplify the nuclear many body problem, such as the cluster approximation. We demonstrate, in explicit examples, certain limits to the validity of the cluster approximation but caution that these limits may be particular to this model where the interactions are of unlimited range

  20. Modeling the ocean effect of geomagnetic storms

    DEFF Research Database (Denmark)

    Olsen, Nils; Kuvshinov, A.

    2004-01-01

    At coastal sites, geomagnetic variations for periods shorter than a few days are strongly distorted by the conductivity of the nearby sea-water. This phenomena, known as the ocean (or coast) effect, is strongest in the magnetic vertical component. We demonstrate the ability to predict the ocean...... if the oceans are considered. Our analysis also indicates a significant local time asymmetry (i.e., contributions from spherical harmonics other than P-I(0)), especially during the main phase of the storm....

  1. THE VIRTUAL UNIVERSITY MODEL AS THE MAIN PLATFORM FOR IMPLEMENTATION OF PROFESSIONAL RETRAINING PROGRAM FOR TEACHERS BY THE EXMPLE OF SYRIAN VIRTUAL UNIVERSITY

    Directory of Open Access Journals (Sweden)

    K. O. Prosyukova

    2014-09-01

    Full Text Available The interest in virtual education has recently increased in educational environment. Researchers in their scientific activity are focused on the benefits of the “virtual university” or “virtual college” models. But the range of a “virtuality” concept is too wide: some researchers recognize all information technologies in education as virtual means, while the others are looking for the ways to replace education in its general meaning with virtual educational space. The problem of virtual education is also relevant because the application area is boundless: school education, secondary professional education, higher education, training and retraining programs. Thus virtual education is able to become not only the innovative educational model, but also a possible solution to the problem of continuing education. One of the most successful examples in this field is the example of Syrian Virtual University, which has become the pioneer in virtual education in the Middle East region.

  2. A Proposal Of Simulation Model Of A Wind-Steering System For Sailing Yachts, Based On Single-Stage Servo-Pendulum Coupled With Main Rudder

    Directory of Open Access Journals (Sweden)

    Piętak Andrzej

    2015-04-01

    Full Text Available The aim of this study was to investigate possible application of fast design prototyping methods for wind-steering systems used in offshore sailing yachts. The development of such methods would help to speed up the construction work and reduce the scope of necessary experimental research, prior to implementation of the system. In the present work, based on an analysis of existing designs of windvane systems, a preliminary selection of the system configuration has been undertaken, in terms of a compromise between efficiency, performance, and design complexity. Construction design of a single-stage, servo – pendulum system, has been developed by using the Autodesk Inventor design package. Next, based on the design data, a simulation model of the system, has been produced by using Matlab - Simulink software and SimMechanics library. The model was further verified in terms of kinematics mapping with the use of Matlab visualization tools.

  3. Finite element prediction of the swift effect based on Taylor-type polycrystal plasticity models

    OpenAIRE

    Duchene, Laurent; Delannay, L.; Habraken, Anne

    2004-01-01

    This paper describes the main concepts of the stress-strain interpolation model that has been implemented in the non-linear finite element code Lagamine. This model consists in a local description of the yield locus based on the texture of the material through the full constraints Taylor’s model. The prediction of the Swift effect is investigated: the influence of the texture evolution is shown up. The LAMEL model is also investigated for the Swift effect prediction. Peer reviewed

  4. Coupling age-structured stock assessment and fish bioenergetics models: a system of time-varying models for quantifying piscivory patterns during the rapid trophic shift in the main basin of Lake Huron

    Science.gov (United States)

    He, Ji X.; Bence, James R.; Madenjian, Charles P.; Pothoven, Steven A.; Dobiesz, Norine E.; Fielder, David G.; Johnson, James E.; Ebener, Mark P.; Cottrill, Adam R.; Mohr, Lloyd C.; Koproski, Scott R.

    2015-01-01

    We quantified piscivory patterns in the main basin of Lake Huron during 1984–2010 and found that the biomass transfer from prey fish to piscivores remained consistently high despite the rapid major trophic shift in the food webs. We coupled age-structured stock assessment models and fish bioenergetics models for lake trout (Salvelinus namaycush), Chinook salmon (Oncorhynchus tshawytscha), walleye (Sander vitreus), and lake whitefish (Coregonus clupeaformis). The model system also included time-varying parameters or variables of growth, length–mass relations, maturity schedules, energy density, and diets. These time-varying models reflected the dynamic connections that a fish cohort responded to year-to-year ecosystem changes at different ages and body sizes. We found that the ratio of annual predation by lake trout, Chinook salmon, and walleye combined with the biomass indices of age-1 and older alewives (Alosa pseudoharengus) and rainbow smelt (Osmerus mordax) increased more than tenfold during 1987–2010, and such increases in predation pressure were structured by relatively stable biomass of the three piscivores and stepwise declines in the biomass of alewives and rainbow smelt. The piscivore stability was supported by the use of alternative energy pathways and changes in relative composition of the three piscivores. In addition, lake whitefish became a new piscivore by feeding on round goby (Neogobius melanostomus). Their total fish consumption rivaled that of the other piscivores combined, although fish were still a modest proportion of their diet. Overall, the use of alternative energy pathways by piscivores allowed the increases in predation pressure on dominant diet species.

  5. Magnetoelastic effect in an exchange model

    International Nuclear Information System (INIS)

    Vallejo, E.

    2009-01-01

    The effect of the interplay between magnetism, charge ordering and lattice distortion within a like double and super-exchange model is studied in low-dimensional systems. An important magnetoelastic effect that leads to a lattice contraction is presented in conjunction with an analytical minimization for a three-site one-dimensional model. The model is discussed in connection with the magnetism, charge ordering and the contraction of the rungs experimentally observed within the three-leg ladders (3LL) present in the oxyborate Fe 3 O 2 BO 3

  6. Nanoparticles affect PCR primarily via surface interactions with PCR components: using amino-modified silica-coated magnetic nanoparticles as a main model

    Science.gov (United States)

    Nanomaterials have been widely reported to affect the polymerase chain reaction (PCR). However, many studies in which these effects were observed were not comprehensive, and many of the proposed mechanisms have been primarily speculative. In this work, we used amino-modified silica-coated magnetic n...

  7. Random effects models in clinical research

    NARCIS (Netherlands)

    Cleophas, T. J.; Zwinderman, A. H.

    2008-01-01

    BACKGROUND: In clinical trials a fixed effects research model assumes that the patients selected for a specific treatment have the same true quantitative effect and that the differences observed are residual error. If, however, we have reasons to believe that certain patients respond differently

  8. Modelling synergistic effects of appetite regulating hormones

    DEFF Research Database (Denmark)

    Schmidt, Julie Berg; Ritz, Christian

    2016-01-01

    We briefly reviewed one definition of dose addition, which is applicable within the framework of generalized linear models. We established how this definition of dose addition corresponds to effect addition in case only two doses per compound are considered for evaluating synergistic effects. The....... The link between definitions was exemplified for an appetite study where two appetite hormones were studied....

  9. A Markov model for planning and permitting offshore wind energy: A case study of radio-tracked terns in the Gulf of Maine, USA.

    Science.gov (United States)

    Cranmer, Alexana; Smetzer, Jennifer R; Welch, Linda; Baker, Erin

    2017-05-15

    Quantifying and managing the potential adverse wildlife impacts of offshore wind energy is critical for developing offshore wind energy in a sustainable and timely manner, but poses a significant challenge, particularly for small marine birds that are difficult to monitor. We developed a discrete-time Markov model of seabird movement around a colony site parameterized by automated radio telemetry data from common terns (Sterna hirundo) and Arctic terns (S. paradisaea), and derived impact functions that estimate the probability of collision fatality as a function of the distance and bearing of wind turbines from a colony. Our purpose was to develop and demonstrate a new, flexible tool that can be used for specific management and wind-energy planning applications when adequate data are available, rather than inform wind-energy development at this site. We demonstrate how the tool can be used 1) in marine spatial planning exercises to quantitatively identify setback distances under development scenarios given a risk threshold, 2) to examine the ecological and technical trade-offs of development alternatives to facilitate negotiation between objectives, and 3) in the U.S. National Environmental Policy Act (NEPA) process to estimate collision fatality under alternative scenarios. We discuss model limitations and data needs, and highlight opportunities for future model extension and development. We present a highly flexible tool for wind energy planning that can be easily extended to other central place foragers and data sources, and can be updated and improved as new monitoring data arises. Copyright © 2017 Elsevier Ltd. All rights reserved.

  10. Detector of Optical Vortices as the Main Element of the System of Data Transfer: Principles of Operation, Numerical Model, and Influence of Noise and Atmospheric Turbulence

    Directory of Open Access Journals (Sweden)

    Valerii Aksenov

    2012-01-01

    Full Text Available The method is proposed of optical vortex topological charge detection along with a design of a corresponding detector. The developed technique is based on measurements of light field intensity. Mathematical model simulating performance of the detector is described in the paper, and results of numerical experiments are presented which illustrate recognition of a vortex in a turbulent medium and in the presence of amplitude and phase noise in the registered radiation. Influence of shifts of the system optical axis on precision of registration is also considered in the paper.

  11. Two-dimensional sigma models: modelling non-perturbative effects of gauge theories

    International Nuclear Information System (INIS)

    Novikov, V.A.; Shifman, M.A.; Vainshtein, A.I.; Zakharov, V.I.

    1984-01-01

    The review is devoted to a discussion of non-perturbative effects in gauge theories and two-dimensional sigma models. The main emphasis is put on supersymmetric 0(3) sigma model. The instanton-based method for calculating the exact Gell-Mann-Low function and bifermionic condensate is considered in detail. All aspects of the method in simplifying conditions are discussed. The basic points are: the instanton measure from purely classical analysis; a non-renormalization theorem in self-dual external fields; existence of vacuum condensates and their compatibility with supersymmetry

  12. Atmospheric greenhouse effect - simple model; Atmosfaerens drivhuseffekt - enkel modell

    Energy Technology Data Exchange (ETDEWEB)

    Kanestroem, Ingolf; Henriksen, Thormod

    2011-07-01

    The article shows a simple model for the atmospheric greenhouse effect based on consideration of both the sun and earth as 'black bodies', so that the physical laws that apply to them, may be used. Furthermore, explained why some gases are greenhouse gases, but other gases in the atmosphere has no greenhouse effect. But first, some important concepts and physical laws encountered in the article, are repeated. (AG)

  13. Effects of a community-oriented obesity prevention programme on indicators of body fatness in preschool and primary school children. Main results from the IDEFICS study.

    Science.gov (United States)

    De Henauw, S; Huybrechts, I; De Bourdeaudhuij, I; Bammann, K; Barba, G; Lissner, L; Mårild, S; Molnár, D; Moreno, L A; Pigeot, I; Tornaritis, M; Veidebaum, T; Verbestel, V; Ahrens, W

    2015-12-01

    Childhood obesity is a major public health concern but evidence-based approaches to tackle this epidemic sustainably are still lacking. The Identification and prevention of Dietary- and lifestyle-induced health EFfects In Children and infantS (IDEFICS) study investigated the aetiology of childhood obesity and developed a primary prevention programme. Here, we report on the effects of the IDEFICS intervention on indicators of body fatness. The intervention modules addressed the community, school and parental level, focusing on diet, physical activity and stress-related lifestyle factors. A cohort of 16,228 children aged 2-9.9 years - about 2000 per country - was equally divided over intervention and control regions. (Participating countries were Sweden, Germany, Estonia, Hungary, Cyprus, Italy, Spain and Belgium.) We compared the prevalence of overweight/obesity and mean values of body mass index z-score, per cent body fat and waist-to-height ratio over 2 years of follow-up. Mixed models adjusting for age and socioeconomic status of the parents and with an additional random effect for country accounted for the clustered study design. The prevalence of overweight and obesity increased in both the intervention and control group from 18.0% at baseline to 22.9% at follow-up in the control group and from 19.0% to 23.6% in the intervention group. The difference in changes between control and intervention was not statistically significant. For the cohort as a whole, the changes in indicators of body fatness did not show any clinically relevant differences between the intervention and control groups. Changes in favour of intervention treatment in some indicators were counterbalanced by changes in favour of the control group in some other indicators. Over the 2-year-observation period, the IDEFICS primary prevention programme for childhood obesity has not been successful in reducing the prevalence of overweight and obesity nor in improving indicators of body fatness in

  14. Mixed-effects regression models in linguistics

    CERN Document Server

    Heylen, Kris; Geeraerts, Dirk

    2018-01-01

    When data consist of grouped observations or clusters, and there is a risk that measurements within the same group are not independent, group-specific random effects can be added to a regression model in order to account for such within-group associations. Regression models that contain such group-specific random effects are called mixed-effects regression models, or simply mixed models. Mixed models are a versatile tool that can handle both balanced and unbalanced datasets and that can also be applied when several layers of grouping are present in the data; these layers can either be nested or crossed.  In linguistics, as in many other fields, the use of mixed models has gained ground rapidly over the last decade. This methodological evolution enables us to build more sophisticated and arguably more realistic models, but, due to its technical complexity, also introduces new challenges. This volume brings together a number of promising new evolutions in the use of mixed models in linguistics, but also addres...

  15. Kovacs effect in solvable model glasses

    International Nuclear Information System (INIS)

    Aquino, Gerardo; Leuzzi, Luca; Nieuwenhuizen, Theo M

    2006-01-01

    The Kovacs protocol, based on the temperature shift experiment originally conceived by A.J. Kovacs and applied on glassy polymers, is implemented in an exactly solvable model with facilitated dynamics. This model is based on interacting fast and slow modes represented respectively by spherical spins and harmonic oscillator variables. Due to this fundamental property and to slow dynamics, the model reproduces the characteristic nonmonotonic evolution known as the 'Kovacs effect', observed in polymers, spin glasses, in granular materials and models of molecular liquids, when similar experimental protocols are implemented

  16. Kovacs effect in solvable model glasses

    Science.gov (United States)

    Aquino, Gerardo; Leuzzi, Luca; Nieuwenhuizen, Theo M.

    2006-05-01

    The Kovacs protocol, based on the temperature shift experiment originally conceived by A.J. Kovacs and applied on glassy polymers [1], is implemented in an exactly solvable model with facilitated dynamics. This model is based on interacting fast and slow modes represented respectively by spherical spins and harmonic oscillator variables. Due to this fundamental property and to slow dynamics, the model reproduces the characteristic nonmonotonic evolution known as the ''Kovacs effect'', observed in polymers, spin glasses, in granular materials and models of molecular liquids, when similar experimental protocols are implemented.

  17. “Green” fuel tax on private transportation services and subsidies to electric energy. A model-based assessment for the main European countries

    International Nuclear Information System (INIS)

    Bartocci, Anna; Pisani, Massimiliano

    2013-01-01

    This paper evaluates the environmental and macroeconomic implications for France, Germany, Italy and Spain of taxing motor vehicle fuels for private transportation, a sector not subject to the Emissions Trading System, so as to reduce taxes on electricity consumption and increase subsidies to renewable sources of electricity generation. The assessment is based on a dynamic general equilibrium model calibrated for each of the four countries. The results suggest that the measures posited will reduce carbon dioxide emissions in the transportation sector and favor the development of electricity generation from renewable sources, thus limiting the growth of emissions from electricity generation. The measures do not jeopardize economic activity. The results are robust whether implementation is unilateral in one country or simultaneous throughout the EU. - Highlights: • The European Union's Agenda 2020 calls for member countries to reduce greenhouse gas emissions and increase renewable energy. • We evaluate implications in the EU of taxing fuels for private transportation, reducing taxes on electricity and increase subsidies to renewable sources of electricity. • The assessment is based on a dynamic general equilibrium model. • The measures reduce emissions, in particular in the transportation sector, favor electricity generation from renewable sources and do not jeopardize economic activity

  18. Effect of potato used as a trap crop on potato cyst nematodes and other soil pathogens and on the growth of a subsequent main potato crop

    NARCIS (Netherlands)

    Scholte, K.

    2000-01-01

    A field experiment in which main-crop potatoes were grown every other year was conducted on a sandy soil from 1994 to 1999. The aim of the experiment was to control soil-borne pathogens of potato with ecologically sound methods. Potato grown as a trap crop from the end of April to the end of June (8

  19. Modeling bubble condenser containment with computer code COCOSYS: post-test calculations of the main steam line break experiment at ELECTROGORSK BC V-213 test facility

    International Nuclear Information System (INIS)

    Lola, I.; Gromov, G.; Gumenyuk, D.; Pustovit, V.; Sholomitsky, S.; Wolff, H.; Arndt, S.; Blinkov, V.; Osokin, G.; Melikhov, O.; Melikhov, V.; Sokoline, A.

    2005-01-01

    Containment of the WWER-440 Model 213 nuclear power plant features a Bubble Condenser, a complex passive pressure suppression system, intended to limit pressure rise in the containment during accidents. Due to lack of experimental evidence of its successful operation in the original design documentation, the performance of this system under accidents with ruptures of large high-energy pipes of the primary and secondary sides remains a known safety concern for this containment type. Therefore, a number of research and analytical studies have been conducted by the countries operating WWER-440 reactors and their Western partners in the recent years to verify Bubble Condenser operation under accident conditions. Comprehensive experimental research studies at the Electrogorsk BC V-213 test facility, commissioned in 1999 in Electrogorsk Research and Engineering Centre (EREC), constitute essential part of these efforts. Nowadays this is the only operating large-scale facility enabling integral tests on investigation of the Bubble Condenser performance. Several large international research projects, conducted at this facility in 1999-2003, have covered a spectrum of pipe break accidents. These experiments have substantially improved understanding of the overall system performance and thermal hydraulic phenomena in the Bubble Condenser Containment, and provided valuable information for validating containment codes against experimental results. One of the recent experiments, denoted as SLB-G02, has simulated steam line break. The results of this experiment are of especial value for the engineers working in the area of computer code application for WWER-440 containment analyses, giving an opportunity to verify validity of the code predictions and identify possibilities for model improvement. This paper describes the results of the post-test calculations of the SLB-G02 experiment, conducted as a joint effort of GRS, Germany and Ukrainian technical support organizations for

  20. Partitioning of the water budget in the main river basins in High Mountain Asia with GRACE, model output, and other observations.

    Science.gov (United States)

    Velicogna, I.; Ciraci, E.; Grogan, D. S.; Lammers, R. B.

    2017-12-01

    Access to freshwater is important as world populations grow, especially in High Mountain Asia, where glaciers are a significant component of the freshwater resources, particularly in summer. Glaciers are sensitive to climate perturbations and affected by climate change. Our understanding of the contribution of glacier runoff to specific watersheds, and projections of glacier runoff in a warming climate, are critical to inform decisions, management and policy development. Here, we quantify changes in glacier mass balance in HMA using GRACE data and determine their contribution to river basin hydrology. We use GRACE data to estimate the HMA glacier mass mas balance and compare the results with changes in total water storage (TWS) for the major watersheds in the HMA regions. We designed ad-hoc mascon configurations to calculate the upstream glacier change in mass balance and contribution to major river basins water supply, determined appropriate corrections and uncertainties for the signal and evaluated the results via comparison with the Water Balance Model (WBM) output and other data (re-analysis data and satellite-derived precipitation and evapotranspiration). Most of the glacier loss is from the Himalaya region (Himalaya, Hengduan Shan S and E Tibet), whereas the western sectors (E and W Tien Shan; and Hindu Kush, Karakoram, W Kunlun, Pamir, Hissar Alay) experienced smaller losses but with larger interannual variability driven by changes in the westerly-driven winter precipitation. For the Indus basin, to evaluate the glacier contribution to the total water budget, we examine the contribution of the upper basin to the lower basin TWS change. Over the Upper Indus basin, we find that the seasonal decline in total water storage between May and September averages 88 Gt during 2002-2012. TRMM cumulative precipitation amounts to 119 Gt, leaving a runoff and evapotranspiration component of 207 Gt. This estimate compares well with an estimate for the WBM modeled runoff of

  1. Monitoring and modelling of thermo-hydro-mechanical processes - main results of a heater experiment at the Mont Terri underground rock laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Ingeborg, G.; Alheid, H.J. [BGR - Federal Institute for Geosciences and Natural Resources, Hannover (Germany); Jockwerz, N. [Gesellschaft fur Anlagen- und Reaktorsicherheit (GRS) - Final Repository Research Division, Braunschweig (Germany); Mayor, J.C. [ENRESA - Empresa Nacional des Residuos Radioactivos, Madrid (Spain); Garcia-Siner, J.L. [AITEMIN -Asociacion para la Investigacion y Desarrollo Industrial de los Recursos Naturales, Madrid, (Spain); Alonso, E. [CIMNE - Centre Internacional de Metodos Numerics en Ingenyeria, UPC, Barcelona (Spain); Weber, H.P. [NAGRA - National Cooperative for the Disposal of Radioactive Waste, Wettingen (Switzerland); Plotze, M. [ETHZ - Swiss Federal Institute of Technology Zurich, IGT, Zurich, (Switzerland); Klubertanz, G. [COLENCO Power Engineering Ltd., Baden (Switzerland)

    2005-07-01

    The long-term safety of permanent underground repositories relies on a combination of engineered and geological barriers, so that the interactions between the barriers in response to conditions expected in a high-level waste repository need to be identified and fully understood. Co-financed by the European Community, a heater experiment was realized on a pilot plant scale at the underground laboratory in Mont Terri, Switzerland. The experiment was accompanied by an extensive programme of continuous monitoring, experimental investigations on-site as well as in laboratories, and numerical modelling of the coupled thermo-hydro-mechanical processes. Heat-producing waste was simulated by a heater element of 10 cm diameter, held at a constant surface temperature of 100 C. The heater element (length 2 m) operated in a vertical borehole of 7 m depth at 4 to 6 m depth. It was embedded in a geotechnical barrier of pre-compacted bentonite blocks (outer diameter 30 cm) that were irrigated for 35 months before the heating phase (duration 18 months) began. The host rock is a highly consolidated stiff Jurassic clay stone (Opalinus Clay). After the heating phase, the vicinity of the heater element was explored by seismic, hydraulic, and geotechnical tests to investigate if the heating had induced changes in the Opalinus Clay. Additionally, rock mechanic specimens were tested in the laboratory. Finally, the experiment was dismantled to provide laboratory specimens of post - heating buffer and host rock material. The bentonite blocks were thoroughly wetted at the time of the dismantling. The volume increase amounted to 5 to 9% and was thus below the bentonite potential. Geo-electrical measurements showed no decrease of the water content in the vicinity of the heater during the heating phase. Decreasing energy input to the heater element over time suggests hence, that the bentonite dried leading to a decrease of its thermal conductivity. Gas release during the heating period occurred

  2. Development of Dynamic Environmental Effect Calculation Model

    International Nuclear Information System (INIS)

    Jeong, Chang Joon; Ko, Won Il

    2010-01-01

    The short-term, long-term decay heat, and radioactivity are considered as main environmental parameters of SF and HLA. In this study, the dynamic calculation models for radioactivity, short-term decay heat, and long-term heat load of the SF are developed and incorporated into the Doneness code. The spent fuel accumulation has become a major issue for sustainable operation of nuclear power plants. If a once-through fuel cycle is selected, the SF will be disposed into the repository. Otherwise, in case of fast reactor or reuse cycle, the SF will be reprocessed and the high level waste will be disposed

  3. [Simulating climate change effect on aboveground carbon sequestration rates of main broadleaved trees in the Xiaoxing'an Mountains area, Northeast China].

    Science.gov (United States)

    Ma, Jun; Bu, Rencang; Deng, Hua-Wei; Hu, Yuan-Man; Qin, Qin; Han, Feng-Lin

    2014-09-01

    LANDIS Pro 7.0 model was used to simulate the dynamics of aboveground biomass of ten broadleaved tree species in the Xiao Xing' an Mountains area under current and various climate change scenarios from 2000 to 2200, and carbon content coefficients (CCCs) were coupled to cal- culate the aboveground carbon sequestration rates (ACSRs) of these species. The results showed that in the initial year of simulation, the biomasses and their proportions of Fraxinus mandshurica, Phellodendron amurense, Quercus mongolica, Ulmus propinqua, and Acer mono were relatively low, while those of Betula costata, Betula platyphylla, and Populus davidiana were higher. A trend of rise after decline occurred in ACSR for pioneer species in the mid and late periods of simulation years, but ACSRs for the other broadleaved tree species were considerably complex. The ACSRs of Q. mongolica and Tilla amurensis fluctuated in the ranges of -0.05-0.25 t · hm(-2) · 10 a(-1) and 0.16-1.29 t · hm(-2) · 10 a(-1) in simulation years, respectively. The ACSRs of F. mandshurica, U. propinqua, A. mono, and B. costata showed a trend of decline after rise in late simulation years. There were significant differences in ACSR for P. amurense and B. davurica among various climate change scenarios in the periods of 2050-2100 and 2150-2200, while no significant difference in ACSR for the other species would be detected. Difference of sensitivity of various species in ACSR for future climate scenarios in the Small Khingan Mountains area existed. However, the un- certainty of future climates would not yield significant difference in ACSR for most broadleaved tree species. Moreover, a time lag would exist in the process of climate change effects on temperate forest's ACSR.

  4. Anti-inflammatory and antiedematogenic activity of the Ocimum basilicum essential oil and its main compound estragole: In vivo mouse models.

    Science.gov (United States)

    Rodrigues, Lindaiane Bezerra; Oliveira Brito Pereira Bezerra Martins, Anita; Cesário, Francisco Rafael Alves Santana; Ferreira E Castro, Fyama; de Albuquerque, Thaís Rodrigues; Martins Fernandes, Maria Neyze; Fernandes da Silva, Bruno Anderson; Quintans Júnior, Lucindo José; da Costa, José Galberto Martins; Melo Coutinho, Henrique Douglas; Barbosa, Roseli; Alencar de Menezes, Irwin Rose

    2016-09-25

    The genus Ocimum are used in cooking, however, their essential oils are utilized in traditional medicine as aromatherapy. The present study was carried out to investigate the chemical composition and systemic anti-inflammatory activity of the Ocimum basilicum essential oil (EOOB) and its major component estragole, as well as its possible mechanisms of action. The Ocimum basilicum essential oil was obtained by hydrodistillation and analyzed by GC-MS. The anti-inflammatory action was verified using acute and chronic in vivo tests as paw edema, peritonitis, and vascular permeability and granulomatous inflammation model. The anti-inflammatory mechanism of action was analyzed by the participation of histamine and arachidonic acid pathways. The chemical profile analysis identified fourteen components present in the essential oil, within them: estragole (60.96%). The in vivo test results show that treatment with EOOB (100 and 50 mg/kg) and estragole (60 and 30 mg/kg) significantly reduced paw edema induced by carrageenan and dextran. The smallest doses of EOOB (50 mg/kg) and estragole (30 mg/kg) showed efficacy in the reduction of paw edema induced by histamine and arachidonic acid, vascular permeability inhibition and leukocyte emigration in the peritoneal fluid. Theses doses were capable of reducing the chronic inflammatory process. The results observed between the EOOB and estragole demonstrate efficacy in anti-inflammatory activity, however, the essential oil is more efficacious in the acute and chronic anti-inflammatory action. This study confirms the therapeutic potential of this plant and reinforces the validity of its use in popular medicine. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  5. ANSYS Modeling of Hydrostatic Stress Effects

    Science.gov (United States)

    Allen, Phillip A.

    1999-01-01

    Classical metal plasticity theory assumes that hydrostatic pressure has no effect on the yield and postyield behavior of metals. Plasticity textbooks, from the earliest to the most modem, infer that there is no hydrostatic effect on the yielding of metals, and even modem finite element programs direct the user to assume the same. The object of this study is to use the von Mises and Drucker-Prager failure theory constitutive models in the finite element program ANSYS to see how well they model conditions of varying hydrostatic pressure. Data is presented for notched round bar (NRB) and "L" shaped tensile specimens. Similar results from finite element models in ABAQUS are shown for comparison. It is shown that when dealing with geometries having a high hydrostatic stress influence, constitutive models that have a functional dependence on hydrostatic stress are more accurate in predicting material behavior than those that are independent of hydrostatic stress.

  6. Tissue Acoustoelectric Effect Modeling From Solid Mechanics Theory.

    Science.gov (United States)

    Song, Xizi; Qin, Yexian; Xu, Yanbin; Ingram, Pier; Witte, Russell S; Dong, Feng

    2017-10-01

    The acoustoelectric (AE) effect is a basic physical phenomenon, which underlies the changes made in the conductivity of a medium by the application of focused ultrasound. Recently, based on the AE effect, several biomedical imaging techniques have been widely studied, such as ultrasound-modulated electrical impedance tomography and ultrasound current source density imaging. To further investigate the mechanism of the AE effect in tissue and to provide guidance for such techniques, we have modeled the tissue AE effect using the theory of solid mechanics. Both bulk compression and thermal expansion of tissue are considered and discussed. Computation simulation shows that the muscle AE effect result, conductivity change rate, is 3.26×10 -3 with 4.3-MPa peak pressure, satisfying the theoretical value. Bulk compression plays the main role for muscle AE effect, while thermal expansion makes almost no contribution to it. In addition, the AE signals of porcine muscle are measured at different focal positions. With the same magnitude order and the same change trend, the experiment result confirms that the simulation result is effective. Both simulation and experimental results validate that tissue AE effect modeling using solid mechanics theory is feasible, which is of significance for the further development of related biomedical imaging techniques.

  7. Mortise terrorism on the main pipelines

    Science.gov (United States)

    Komarov, V. A.; Nigrey, N. N.; Bronnikov, D. A.; Nigrey, A. A.

    2018-01-01

    The research aim of the work is to analyze the effectiveness of the methods of physical protection of main pipelines proposed in the article from the "mortise terrorism" A mathematical model has been developed that made it possible to predict the dynamics of "mortise terrorism" in the short term. An analysis of the effectiveness of physical protection methods proposed in the article to prevent unauthorized impacts on the objects under investigation is given. A variant of a video analytics system has been developed that allows detecting violators with recognition of the types of work they perform at a distance of 150 meters in conditions of complex natural backgrounds and precipitation. Probability of detection is 0.959.

  8. Generalized Born Models of Macromolecular Solvation Effects

    Science.gov (United States)

    Bashford, Donald; Case, David A.

    2000-10-01

    It would often be useful in computer simulations to use a simple description of solvation effects, instead of explicitly representing the individual solvent molecules. Continuum dielectric models often work well in describing the thermodynamic aspects of aqueous solvation, and approximations to such models that avoid the need to solve the Poisson equation are attractive because of their computational efficiency. Here we give an overview of one such approximation, the generalized Born model, which is simple and fast enough to be used for molecular dynamics simulations of proteins and nucleic acids. We discuss its strengths and weaknesses, both for its fidelity to the underlying continuum model and for its ability to replace explicit consideration of solvent molecules in macromolecular simulations. We focus particularly on versions of the generalized Born model that have a pair-wise analytical form, and therefore fit most naturally into conventional molecular mechanics calculations.

  9. Main challenges of residential areas

    Directory of Open Access Journals (Sweden)

    Oana Luca

    2017-06-01

    Full Text Available The present article is a position paper aiming to initiate a professional debate related to the aspects related to the urban dysfunctions leading to the wear of the residential areas. The paper proposes a definition of the wear process, identify the main causes leading to its occurrence and propose a number of solutions to neutralise the dysfunctions. The three wearing phases of residential areas components are emphasized, exploring their lifecycle. In order to perform the study of urban wear, the status of the residential areas components can be established and monitored, and also the variables of the function that can mathematically model the specific wear process may be considered. The paper is considered a first step for the model adjustment, to be tested and validated in the following steps. Based on the mathematical method and model, there can be created, in a potential future research, the possibility of determining the precarity degree for residential areas/neighbourhoods and cities, by minimising the subjective component of the analyses preceding the decision for renovation or regeneration.

  10. [Effects of wheat-oilseed rape intercropping and methyl salicylate application on the spatial distributions of Sitobion avenae and its main natural enemies].

    Science.gov (United States)

    Dong, Jie; Liu, Ying-Jie; Wang, Guang; Liu, Yong

    2012-07-01

    A field investigation was conducted on the spatial distributions of Sitobion avenae and its main natural enemies under wheat-oilseed rape intercropping and methyl salicylate application. With the development of wheat plant, an alternation from aggregation to uniform was observed in the spatial distribution of S. avenae under the intercropping and methyl salicylate application, being more obvious under the interaction of the two practices. The spatial distribution of S. avenae natural enemies was in accordance with that of the aphid. These results could be used for the reference of sampling investigation and forecast of wheat aphid and its natural enemies in field.

  11. Disorder effects in the t-J model

    International Nuclear Information System (INIS)

    Caprara, S.; De Palo, S.; Castellani, C.; Di Castro, C.; Grilli, M.

    1995-01-01

    We investigate the effects of disorder in the single-band t-J model, mainly devoting our analysis to the superconducting phases with d-wave or s-wave symmetry. We present evidence that, in the presence of strong correlation with reduced bandwidth and Van Hove singularity in the density of states, a self-consistent approach for the self-energy associated to the impurities is required. Numerical estimates of the reduction of the critical temperature with disorder are given. When a constant imaginary part of the self-energy is taken, avoiding self-consistency, the reduction of the critical temperature is overestimated

  12. A single quark effective potential model

    International Nuclear Information System (INIS)

    Bodmann, B.E.J.; Vasconcellos, C.A.Z.

    1994-01-01

    In the present work we construct a radial spherical symmetric single quark potential model for the nucleon, consistent with asymptotic freedom and confinement. The quark mass enters as potential parameter and that way induces indirectly an isospin dependence in the interaction. As a consequence, a contribution to the negative charge square radius of the neutron arises an an effect of the quark core, which simulates an isospin symmetry breaking effect in the nucleon due to strong interaction. (author)

  13. Application of Hierarchical Linear Models/Linear Mixed-Effects Models in School Effectiveness Research

    Science.gov (United States)

    Ker, H. W.

    2014-01-01

    Multilevel data are very common in educational research. Hierarchical linear models/linear mixed-effects models (HLMs/LMEs) are often utilized to analyze multilevel data nowadays. This paper discusses the problems of utilizing ordinary regressions for modeling multilevel educational data, compare the data analytic results from three regression…

  14. Random effect selection in generalised linear models

    DEFF Research Database (Denmark)

    Denwood, Matt; Houe, Hans; Forkman, Björn

    We analysed abattoir recordings of meat inspection codes with possible relevance to onfarm animal welfare in cattle. Random effects logistic regression models were used to describe individual-level data obtained from 461,406 cattle slaughtered in Denmark. Our results demonstrate that the largest...

  15. Modelling vocal anatomy's significant effect on speech

    NARCIS (Netherlands)

    de Boer, B.

    2010-01-01

    This paper investigates the effect of larynx position on the articulatory abilities of a humanlike vocal tract. Previous work has investigated models that were built to resemble the anatomy of existing species or fossil ancestors. This has led to conflicting conclusions about the relation between

  16. COMSOL modelling of the acoustoelastic effect

    International Nuclear Information System (INIS)

    Watson, N J; Hazlehurst, T; Povey, M J W; Drennan, A; Seaman, P

    2015-01-01

    Many structural components are subjected to either constant or temporal mechanical loads, such as a suspension bridge bolts and rail tracks. Methods are required to accurately and efficiently measure the stresses experienced by these components to ensure they can continue to operate in an effective and safe manner. Acoustic techniques can be used to monitor the stress in a solid material via the acoustoelastic effect. This is the stress dependence of the acoustic velocity in an elastic media. This work develops a multiphysics computational model to study the acoustoelastic effect in a three point bending system. A simple linear relationship was utilised to represent the stress effect on the acoustic velocity. The simulation results were compared with experimental results and the same general trend was observed. An increase in applied load resulted in a greater difference between the time of flight of two transducers at the top and bottom of a component and perpendicular to the applied load. However, there were quantitative differences between the model and the experiment. The model was used to investigate different ultrasound transducer location and operating frequency, highlighting the benefit of modelling tools for the design of acoustic equipment

  17. Effective models for excitons in carbon nanotubes

    DEFF Research Database (Denmark)

    Cornean, Horia; Duclos, Pierre; Ricaud, Benjamin

    We analyse the low lying spectrum of a model of excitons in carbon nanotubes. Consider two particles with a Coulomb self-interaction, placed on an infinitely long cylinder. If the cylinder radius becomes small, the low lying spectrum is well described by a one-dimensional effective Hamiltonian...

  18. BUSINESS MODELS FOR INCREASING TECHNOLOGICAL TRANSFER EFFECTIVENESS

    Directory of Open Access Journals (Sweden)

    Simina FULGA

    2016-05-01

    Full Text Available The present paper is devoted to analyze the appropriate recommendations to increase the effectiveness of technology transfer organizations (centers from ReNITT, by using the specific instruments of Business Model Canvas, associated to the technological transfer value chain for the value added services addressed to their clients and according to a continuously improved competitive strategy over competition analysis.

  19. Main approaches to the study of loss

    Directory of Open Access Journals (Sweden)

    Burina E. A.

    2016-07-01

    Full Text Available this article presents the main approaches to the concepts of grief and loss study. The article describes the contribution of E. Lindemann, Z. Freud, J. Bowlby, F.E. Vasiluk, and E. Kubler-Ross. The research also contains the main forms of grief and some stadial models within the scope of problematics.

  20. Reception in Chile of the United Nations Commission on International Trade Law Model Law on Cross-Border Insolvency: Brief analysis of the center of main interests of the debtor as a new connecting factor

    Directory of Open Access Journals (Sweden)

    Jeremy Daniel Levy Morchio

    2015-12-01

    Full Text Available This article analyze the United Nations Commission on International Trade Law (UNCITRAL Model Law on Cross-border Insolvency and its incorporation into national law by means of the entry into force of the new Law of Insolvency and Re-entrepreneurship, paying special attention to the concept of center of main interests of the debtor, as a new factor of connection between jurisdictions. For this, we will begin with the situation of cross-border insolvency in Chile prior to the new law, will analyze the origin, structure and objectives of the model law and the way in which was introduced in Chile, to finally study the concept of center of main interests of the debtor.