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Sample records for model includes effects

  1. Enhanced battery model including temperature effects

    NARCIS (Netherlands)

    Rosca, B.; Wilkins, S.

    2013-01-01

    Within electric and hybrid vehicles, batteries are used to provide/buffer the energy required for driving. However, battery performance varies throughout the temperature range specific to automotive applications, and as such, models that describe this behaviour are required. This paper presents a

  2. Dynamic hysteresis modeling including skin effect using diffusion equation model

    Energy Technology Data Exchange (ETDEWEB)

    Hamada, Souad, E-mail: souadhamada@yahoo.fr [LSP-IE: Research Laboratory, Electrical Engineering Department, University of Batna, 05000 Batna (Algeria); Louai, Fatima Zohra, E-mail: fz_louai@yahoo.com [LSP-IE: Research Laboratory, Electrical Engineering Department, University of Batna, 05000 Batna (Algeria); Nait-Said, Nasreddine, E-mail: n_naitsaid@yahoo.com [LSP-IE: Research Laboratory, Electrical Engineering Department, University of Batna, 05000 Batna (Algeria); Benabou, Abdelkader, E-mail: Abdelkader.Benabou@univ-lille1.fr [L2EP, Université de Lille1, 59655 Villeneuve d’Ascq (France)

    2016-07-15

    An improved dynamic hysteresis model is proposed for the prediction of hysteresis loop of electrical steel up to mean frequencies, taking into account the skin effect. In previous works, the analytical solution of the diffusion equation for low frequency (DELF) was coupled with the inverse static Jiles-Atherton (JA) model in order to represent the hysteresis behavior for a lamination. In the present paper, this approach is improved to ensure the reproducibility of measured hysteresis loops at mean frequency. The results of simulation are compared with the experimental ones. The selected results for frequencies 50 Hz, 100 Hz, 200 Hz and 400 Hz are presented and discussed.

  3. A hydrodynamic model for granular material flows including segregation effects

    Directory of Open Access Journals (Sweden)

    Gilberg Dominik

    2017-01-01

    Full Text Available The simulation of granular flows including segregation effects in large industrial processes using particle methods is accurate, but very time-consuming. To overcome the long computation times a macroscopic model is a natural choice. Therefore, we couple a mixture theory based segregation model to a hydrodynamic model of Navier-Stokes-type, describing the flow behavior of the granular material. The granular flow model is a hybrid model derived from kinetic theory and a soil mechanical approach to cover the regime of fast dilute flow, as well as slow dense flow, where the density of the granular material is close to the maximum packing density. Originally, the segregation model has been formulated by Thornton and Gray for idealized avalanches. It is modified and adapted to be in the preferred form for the coupling. In the final coupled model the segregation process depends on the local state of the granular system. On the other hand, the granular system changes as differently mixed regions of the granular material differ i.e. in the packing density. For the modeling process the focus lies on dry granular material flows of two particle types differing only in size but can be easily extended to arbitrary granular mixtures of different particle size and density. To solve the coupled system a finite volume approach is used. To test the model the rotational mixing of small and large particles in a tumbler is simulated.

  4. A hydrodynamic model for granular material flows including segregation effects

    Science.gov (United States)

    Gilberg, Dominik; Klar, Axel; Steiner, Konrad

    2017-06-01

    The simulation of granular flows including segregation effects in large industrial processes using particle methods is accurate, but very time-consuming. To overcome the long computation times a macroscopic model is a natural choice. Therefore, we couple a mixture theory based segregation model to a hydrodynamic model of Navier-Stokes-type, describing the flow behavior of the granular material. The granular flow model is a hybrid model derived from kinetic theory and a soil mechanical approach to cover the regime of fast dilute flow, as well as slow dense flow, where the density of the granular material is close to the maximum packing density. Originally, the segregation model has been formulated by Thornton and Gray for idealized avalanches. It is modified and adapted to be in the preferred form for the coupling. In the final coupled model the segregation process depends on the local state of the granular system. On the other hand, the granular system changes as differently mixed regions of the granular material differ i.e. in the packing density. For the modeling process the focus lies on dry granular material flows of two particle types differing only in size but can be easily extended to arbitrary granular mixtures of different particle size and density. To solve the coupled system a finite volume approach is used. To test the model the rotational mixing of small and large particles in a tumbler is simulated.

  5. Modeling Electric Double-Layers Including Chemical Reaction Effects

    DEFF Research Database (Denmark)

    Paz-Garcia, Juan Manuel; Johannesson, Björn; Ottosen, Lisbeth M.

    2014-01-01

    A physicochemical and numerical model for the transient formation of an electric double-layer between an electrolyte and a chemically-active flat surface is presented, based on a finite elements integration of the nonlinear Nernst-Planck-Poisson model including chemical reactions. The model works...

  6. Modeling heart rate variability including the effect of sleep stages

    Science.gov (United States)

    Soliński, Mateusz; Gierałtowski, Jan; Żebrowski, Jan

    2016-02-01

    We propose a model for heart rate variability (HRV) of a healthy individual during sleep with the assumption that the heart rate variability is predominantly a random process. Autonomic nervous system activity has different properties during different sleep stages, and this affects many physiological systems including the cardiovascular system. Different properties of HRV can be observed during each particular sleep stage. We believe that taking into account the sleep architecture is crucial for modeling the human nighttime HRV. The stochastic model of HRV introduced by Kantelhardt et al. was used as the initial starting point. We studied the statistical properties of sleep in healthy adults, analyzing 30 polysomnographic recordings, which provided realistic information about sleep architecture. Next, we generated synthetic hypnograms and included them in the modeling of nighttime RR interval series. The results of standard HRV linear analysis and of nonlinear analysis (Shannon entropy, Poincaré plots, and multiscale multifractal analysis) show that—in comparison with real data—the HRV signals obtained from our model have very similar properties, in particular including the multifractal characteristics at different time scales. The model described in this paper is discussed in the context of normal sleep. However, its construction is such that it should allow to model heart rate variability in sleep disorders. This possibility is briefly discussed.

  7. A thermal lens model including the Soret effect

    International Nuclear Information System (INIS)

    Cabrera, Humberto; Sira, Eloy; Rahn, Kareem; Garcia-Sucre, Maximo

    2009-01-01

    In this letter we generalize the thermal lens model to account for the Soret effect in binary liquid mixtures. This formalism permits the precise determination of the Soret coefficient in a steady-state situation. The theory is experimentally verified using the measured values in the ethanol/water mixtures. The time evolution of the Soret signal has been used to derive mass-diffusion times from which mass-diffusion coefficients were calculated. (Author)

  8. Modeling of Temperature-Dependent Noise in Silicon Nanowire FETs including Self-Heating Effects

    OpenAIRE

    Anandan, P.; Malathi, N.; Mohankumar, N.

    2014-01-01

    Silicon nanowires are leading the CMOS era towards the downsizing limit and its nature will be effectively suppress the short channel effects. Accurate modeling of thermal noise in nanowires is crucial for RF applications of nano-CMOS emerging technologies. In this work, a perfect temperature-dependent model for silicon nanowires including the self-heating effects has been derived and its effects on device parameters have been observed. The power spectral density as a function of thermal resi...

  9. Modeling of the Direct Current Generator Including the Magnetic Saturation and Temperature Effects

    Directory of Open Access Journals (Sweden)

    Alfonso J. Mercado-Samur

    2013-11-01

    Full Text Available In this paper the inclusion of temperature effect on the field resistance on the direct current generator model DC1A, which is valid to stability studies is proposed. First, the linear generator model is presented, after the effect of magnetic saturation and the change in the resistance value due to temperature produced by the field current are included. The comparison of experimental results and model simulations to validate the model is used. A direct current generator model which is a better representation of the generator is obtained. Visual comparison between simulations and experimental results shows the success of the proposed model, because it presents the lowest error of the compared models. The accuracy of the proposed model is observed via Modified Normalized Sum of Squared Errors index equal to 3.8979%.

  10. Modeling of Temperature-Dependent Noise in Silicon Nanowire FETs including Self-Heating Effects

    Directory of Open Access Journals (Sweden)

    P. Anandan

    2014-01-01

    Full Text Available Silicon nanowires are leading the CMOS era towards the downsizing limit and its nature will be effectively suppress the short channel effects. Accurate modeling of thermal noise in nanowires is crucial for RF applications of nano-CMOS emerging technologies. In this work, a perfect temperature-dependent model for silicon nanowires including the self-heating effects has been derived and its effects on device parameters have been observed. The power spectral density as a function of thermal resistance shows significant improvement as the channel length decreases. The effects of thermal noise including self-heating of the device are explored. Moreover, significant reduction in noise with respect to channel thermal resistance, gate length, and biasing is analyzed.

  11. Situational effects of the school factors included in the dynamic model of educational effectiveness

    Directory of Open Access Journals (Sweden)

    Bert Creemers

    2009-08-01

    Full Text Available We present results of a longitudinal study in which 50 schools, 113 classes and 2,542 Cypriot primary students participated. We tested the validity of the dynamic model of educational effectiveness and especially its assumption that the impact of school factors depends on the current situation of the school and on the type of problems/difficulties the school is facing. Reference is made to the methods used to test this assumption of the dynamic model by measuring school effectiveness in mathematics, Greek language, and religious education over two consecutive school years. The main findings are as follows. School factors were found to have situational effects. Specifically, the development of a school policy for teaching and the school evaluation of policy for teaching were found to have stronger effects in schools where the quality of teaching at classroom level was low. Moreover, time stability in the effectiveness status of schools was identified and thereby changes in the functioning of schools were found not to have a significant impact on changes in the effectiveness status of schools. Implications of the findings for the development of the dynamic model and suggestions for further research are presented.

  12. Including Finite Surface Span Effects in Empirical Jet-Surface Interaction Noise Models

    Science.gov (United States)

    Brown, Clifford A.

    2016-01-01

    The effect of finite span on the jet-surface interaction noise source and the jet mixing noise shielding and reflection effects is considered using recently acquired experimental data. First, the experimental setup and resulting data are presented with particular attention to the role of surface span on far-field noise. These effects are then included in existing empirical models that have previously assumed that all surfaces are semi-infinite. This extended abstract briefly describes the experimental setup and data leaving the empirical modeling aspects for the final paper.

  13. Situational effects of the school factors included in the dynamic model of educational effectiveness

    NARCIS (Netherlands)

    Creerners, Bert; Kyriakides, Leonidas

    We present results of a longitudinal study in which 50 schools, 113 classes and 2,542 Cypriot primary students participated. We tested the validity of the dynamic model of educational effectiveness and especially its assumption that the impact of school factors depends on the current situation of

  14. Modeling of cylindrical surrounding gate MOSFETs including the fringing field effects

    International Nuclear Information System (INIS)

    Gupta, Santosh K.; Baishya, Srimanta

    2013-01-01

    A physically based analytical model for surface potential and threshold voltage including the fringing gate capacitances in cylindrical surround gate (CSG) MOSFETs has been developed. Based on this a subthreshold drain current model has also been derived. This model first computes the charge induced in the drain/source region due to the fringing capacitances and considers an effective charge distribution in the cylindrically extended source/drain region for the development of a simple and compact model. The fringing gate capacitances taken into account are outer fringe capacitance, inner fringe capacitance, overlap capacitance, and sidewall capacitance. The model has been verified with the data extracted from 3D TCAD simulations of CSG MOSFETs and was found to be working satisfactorily. (semiconductor devices)

  15. A new model for including the effect of fly ash on biochemical methane potential.

    Science.gov (United States)

    Gertner, Pablo; Huiliñir, César; Pinto-Villegas, Paula; Castillo, Alejandra; Montalvo, Silvio; Guerrero, Lorna

    2017-10-01

    The modelling of the effect of trace elements on anaerobic digestion, and specifically the effect of fly ash, has been scarcely studied. Thus, the present work was aimed at the development of a new function that allows accumulated methane models to predict the effect of FA on the volume of methane accumulation. For this, purpose five fly ash concentrations (10, 25, 50, 250 and 500mg/L) using raw and pre-treated sewage sludge were used to calibrate the new function, while three fly ash concentrations were used (40, 150 and 350mg/L) for validation. Three models for accumulated methane volume (the modified Gompertz equation, the logistic function, and the transfer function) were evaluated. The results showed that methane production increased in the presence of FA when the sewage sludge was not pre-treated, while with pretreated sludge there is inhibition of methane production at FA concentrations higher than 50mg/L. In the calibration of the proposed function, it fits well with the experimental data under all the conditions, including the inhibition and stimulating zones, with the values of the parameters of the methane production models falling in the range of those reported in the literature. For validation experiments, the model succeeded in representing the behavior of new experiments in both the stimulating and inhibiting zones, with NRMSE and R 2 ranging from 0.3577 to 0.03714 and 0.2209 to 0.9911, respectively. Thus, the proposed model is robust and valid for the studied conditions. Copyright © 2017 Elsevier Ltd. All rights reserved.

  16. Double-gate junctionless transistor model including short-channel effects

    International Nuclear Information System (INIS)

    Paz, B C; Pavanello, M A; Ávila-Herrera, F; Cerdeira, A

    2015-01-01

    This work presents a physically based model for double-gate junctionless transistors (JLTs), continuous in all operation regimes. To describe short-channel transistors, short-channel effects (SCEs), such as increase of the channel potential due to drain bias, carrier velocity saturation and mobility degradation due to vertical and longitudinal electric fields, are included in a previous model developed for long-channel double-gate JLTs. To validate the model, an analysis is made by using three-dimensional numerical simulations performed in a Sentaurus Device Simulator from Synopsys. Different doping concentrations, channel widths and channel lengths are considered in this work. Besides that, the series resistance influence is numerically included and validated for a wide range of source and drain extensions. In order to check if the SCEs are appropriately described, besides drain current, transconductance and output conductance characteristics, the following parameters are analyzed to demonstrate the good agreement between model and simulation and the SCEs occurrence in this technology: threshold voltage (V TH ), subthreshold slope (S) and drain induced barrier lowering. (paper)

  17. CFD simulations and reduced order modeling of a refrigerator compartment including radiation effects

    International Nuclear Information System (INIS)

    Bayer, Ozgur; Oskay, Ruknettin; Paksoy, Akin; Aradag, Selin

    2013-01-01

    Highlights: ► Free convection in a refrigerator is simulated including radiation effects. ► Heat rates are affected drastically when radiation effects are considered. ► 95% of the flow energy can be represented by using one spatial POD mode. - Abstract: Considering the engineering problem of natural convection in domestic refrigerator applications, this study aims to simulate the fluid flow and temperature distribution in a single commercial refrigerator compartment by using the experimentally determined temperature values as the specified constant wall temperature boundary conditions. The free convection in refrigerator applications is evaluated as a three-dimensional (3D), turbulent, transient and coupled non-linear flow problem. Radiation heat transfer mode is also included in the analysis. According to the results, taking radiation effects into consideration does not change the temperature distribution inside the refrigerator significantly; however the heat rates are affected drastically. The flow inside the compartment is further analyzed with a reduced order modeling method called Proper Orthogonal Decomposition (POD) and the energy contents of several spatial and temporal modes that exist in the flow are examined. The results show that approximately 95% of all the flow energy can be represented by only using one spatial mode

  18. Integrated Sachs-Wolfe effect in a quintessence cosmological model: Including anisotropic stress of dark energy

    International Nuclear Information System (INIS)

    Wang, Y. T.; Xu, L. X.; Gui, Y. X.

    2010-01-01

    In this paper, we investigate the integrated Sachs-Wolfe effect in the quintessence cold dark matter model with constant equation of state and constant speed of sound in dark energy rest frame, including dark energy perturbation and its anisotropic stress. Comparing with the ΛCDM model, we find that the integrated Sachs-Wolfe (ISW)-power spectrums are affected by different background evolutions and dark energy perturbation. As we change the speed of sound from 1 to 0 in the quintessence cold dark matter model with given state parameters, it is found that the inclusion of dark energy anisotropic stress makes the variation of magnitude of the ISW source uncertain due to the anticorrelation between the speed of sound and the ratio of dark energy density perturbation contrast to dark matter density perturbation contrast in the ISW-source term. Thus, the magnitude of the ISW-source term is governed by the competition between the alterant multiple of (1+3/2xc-circumflex s 2 ) and that of δ de /δ m with the variation of c-circumflex s 2 .

  19. Modeling of Pem Fuel Cell Systems Including Controls and Reforming Effects for Hybrid Automotive Applications

    National Research Council Canada - National Science Library

    Boettner, Daisie

    2001-01-01

    .... This study develops models for a stand-alone Proton Exchange Membrane (PEM) fuel cell stack, a direct-hydrogen fuel cell system including auxiliaries, and a methanol reforming fuel cell system for integration into a vehicle performance simulator...

  20. Beam dynamics in high intensity cyclotrons including neighboring bunch effects: Model, implementation, and application

    Directory of Open Access Journals (Sweden)

    J. J. Yang (杨建俊

    2010-06-01

    Full Text Available Space-charge effects, being one of the most significant collective effects, play an important role in high intensity cyclotrons. However, for cyclotrons with small turn separation, other existing effects are of equal importance. Interactions of radially neighboring bunches are also present, but their combined effects have not yet been investigated in any great detail. In this paper, a new particle in the cell-based self-consistent numerical simulation model is presented for the first time. The model covers neighboring bunch effects and is implemented in the three-dimensional object-oriented parallel code OPAL-cycl, a flavor of the OPAL framework. We discuss this model together with its implementation and validation. Simulation results are presented from the PSI 590 MeV ring cyclotron in the context of the ongoing high intensity upgrade program, which aims to provide a beam power of 1.8 MW (CW at the target destination.

  1. Including Effects of Water Stress on Dead Organic Matter Decay to a Forest Carbon Model

    Science.gov (United States)

    Kim, H.; Lee, J.; Han, S. H.; Kim, S.; Son, Y.

    2017-12-01

    Decay of dead organic matter is a key process of carbon (C) cycling in forest ecosystems. The change in decay rate depends on temperature sensitivity and moisture conditions. The Forest Biomass and Dead organic matter Carbon (FBDC) model includes a decay sub-model considering temperature sensitivity, yet does not consider moisture conditions as drivers of the decay rate change. This study aimed to improve the FBDC model by including a water stress function to the decay sub-model. Also, soil C sequestration under climate change with the FBDC model including the water stress function was simulated. The water stress functions were determined with data from decomposition study on Quercus variabilis forests and Pinus densiflora forests of Korea, and adjustment parameters of the functions were determined for both species. The water stress functions were based on the ratio of precipitation to potential evapotranspiration. Including the water stress function increased the explained variances of the decay rate by 19% for the Q. variabilis forests and 7% for the P. densiflora forests, respectively. The increase of the explained variances resulted from large difference in temperature range and precipitation range across the decomposition study plots. During the period of experiment, the mean annual temperature range was less than 3°C, while the annual precipitation ranged from 720mm to 1466mm. Application of the water stress functions to the FBDC model constrained increasing trend of temperature sensitivity under climate change, and thus increased the model-estimated soil C sequestration (Mg C ha-1) by 6.6 for the Q. variabilis forests and by 3.1 for the P. densiflora forests, respectively. The addition of water stress functions increased reliability of the decay rate estimation and could contribute to reducing the bias in estimating soil C sequestration under varying moisture condition. Acknowledgement: This study was supported by Korea Forest Service (2017044B10-1719-BB01)

  2. Dusty Plasma Modeling of the Fusion Reactor Sheath Including Collisional-Radiative Effects

    International Nuclear Information System (INIS)

    Dezairi, Aouatif; Samir, Mhamed; Eddahby, Mohamed; Saifaoui, Dennoun; Katsonis, Konstantinos; Berenguer, Chloe

    2008-01-01

    The structure and the behavior of the sheath in Tokamak collisional plasmas has been studied. The sheath is modeled taking into account the presence of the dust 2 and the effects of the charged particle collisions and radiative processes. The latter may allow for optical diagnostics of the plasma.

  3. Effect of neurosteroids on a model lipid bilayer including cholesterol: An Atomic Force Microscopy study.

    Science.gov (United States)

    Sacchi, Mattia; Balleza, Daniel; Vena, Giulia; Puia, Giulia; Facci, Paolo; Alessandrini, Andrea

    2015-05-01

    Amphiphilic molecules which have a biological effect on specific membrane proteins, could also affect lipid bilayer properties possibly resulting in a modulation of the overall membrane behavior. In light of this consideration, it is important to study the possible effects of amphiphilic molecule of pharmacological interest on model systems which recapitulate some of the main properties of the biological plasma membranes. In this work we studied the effect of a neurosteroid, Allopregnanolone (3α,5α-tetrahydroprogesterone or Allo), on a model bilayer composed by the ternary lipid mixture DOPC/bSM/chol. We chose ternary mixtures which present, at room temperature, a phase coexistence of liquid ordered (Lo) and liquid disordered (Ld) domains and which reside near to a critical point. We found that Allo, which is able to strongly partition in the lipid bilayer, induces a marked increase in the bilayer area and modifies the relative proportion of the two phases favoring the Ld phase. We also found that the neurosteroid shifts the miscibility temperature to higher values in a way similarly to what happens when the cholesterol concentration is decreased. Interestingly, an isoform of Allo, isoAllopregnanolone (3β,5α-tetrahydroprogesterone or isoAllo), known to inhibit the effects of Allo on GABAA receptors, has an opposite effect on the bilayer properties. Copyright © 2015 Elsevier B.V. All rights reserved.

  4. An Improved Heat Budget Estimation Including Bottom Effects for General Ocean Circulation Models

    Science.gov (United States)

    Carder, Kendall; Warrior, Hari; Otis, Daniel; Chen, R. F.

    2001-01-01

    This paper studies the effects of the underwater light field on heat-budget calculations of general ocean circulation models for shallow waters. The presence of a bottom significantly alters the estimated heat budget in shallow waters, which affects the corresponding thermal stratification and hence modifies the circulation. Based on the data collected during the COBOP field experiment near the Bahamas, we have used a one-dimensional turbulence closure model to show the influence of the bottom reflection and absorption on the sea surface temperature field. The water depth has an almost one-to-one correlation with the temperature rise. Effects of varying the bottom albedo by replacing the sea grass bed with a coral sand bottom, also has an appreciable effect on the heat budget of the shallow regions. We believe that the differences in the heat budget for the shallow areas will have an influence on the local circulation processes and especially on the evaporative and long-wave heat losses for these areas. The ultimate effects on humidity and cloudiness of the region are expected to be significant as well.

  5. Effect of including decay chains on predictions of equilibrium-type terrestrial food chain models

    International Nuclear Information System (INIS)

    Kirchner, G.

    1990-01-01

    Equilibrium-type food chain models are commonly used for assessing the radiological impact to man from environmental releases of radionuclides. Usually these do not take into account build-up of radioactive decay products during environmental transport. This may be a potential source of underprediction. For estimating consequences of this simplification, the equations of an internationally recognised terrestrial food chain model have been extended to include decay chains of variable length. Example calculations show that for releases from light water reactors as expected both during routine operation and in the case of severe accidents, the build-up of decay products during environmental transport is generally of minor importance. However, a considerable number of radionuclides of potential radiological significance have been identified which show marked contributions of decay products to calculated contamination of human food and resulting radiation dose rates. (author)

  6. Numerical modelling of seawater intrusion in Shenzhen (China) using a 3D density-dependent model including tidal effects

    Science.gov (United States)

    Lu, Wei; Yang, Qingchun; Martín, Jordi D.; Juncosa, Ricardo

    2013-04-01

    During the 1990s, groundwater overexploitation has resulted in seawater intrusion in the coastal aquifer of the Shenzhen city, China. Although water supply facilities have been improved and alleviated seawater intrusion in recent years, groundwater overexploitation is still of great concern in some local areas. In this work we present a three-dimensional density-dependent numerical model developed with the FEFLOW code, which is aimed at simulating the extent of seawater intrusion while including tidal effects and different groundwater pumping scenarios. Model calibration, using waterheads and reported chloride concentration, has been performed based on the data from 14 boreholes, which were monitored from May 2008 to December 2009. A fairly good fitness between the observed and computed values was obtained by a manual trial-and-error method. Model prediction has been carried out forward 3 years with the calibrated model taking into account high, medium and low tide levels and different groundwater exploitation schemes. The model results show that tide-induced seawater intrusion significantly affects the groundwater levels and concentrations near the estuarine of the Dasha river, which implies that an important hydraulic connection exists between this river and groundwater, even considering that some anti-seepage measures were taken in the river bed. Two pumping scenarios were considered in the calibrated model in order to predict the future changes in the water levels and chloride concentration. The numerical results reveal a decreased tendency of seawater intrusion if groundwater exploitation does not reach an upper bound of about 1.32 × 104 m3/d. The model results provide also insights for controlling seawater intrusion in such coastal aquifer systems.

  7. Transverse Crack Modeling and Validation in Rotor Systems, Including Thermal Effects

    Directory of Open Access Journals (Sweden)

    N. Bachschmid

    2003-01-01

    Full Text Available This article describes a model that allows the simulation of the static behavior of a transverse crack in a horizontal rotor under the action of weight and other possible static loads and the dynamic behavior of cracked rotating shaft. The crack breathes—that is, the mechanism of the crack's opening and closing is ruled by the stress on the cracked section exerted by the external loads. In a rotor, the stresses are time-dependent and have a period equal to the period of rotation; thus, the crack periodically breathes. An original, simplified model allows cracks of various shapes to be modeled and thermal stresses to be taken into account, as they may influence the opening and closing mechanism. The proposed method was validated by using two criteria. First the crack's breathing mechanism, simulated by the model, was compared with the results obtained by a nonlinear, threedimensional finite element model calculation, and a good agreement in the results was observed. Then the proposed model allowed the development of the equivalent cracked beam. The results of this model were compared with those obtained by the three-dimensional finite element model. Also in this case, there was a good agreement in the results.

  8. A Two-Dimensional Modeling Procedure to Estimate the Loss Equivalent Resistance Including the Saturation Effect

    Directory of Open Access Journals (Sweden)

    Rosa Ana Salas

    2013-11-01

    Full Text Available We propose a modeling procedure specifically designed for a ferrite inductor excited by a waveform in time domain. We estimate the loss resistance in the core (parameter of the electrical model of the inductor by means of a Finite Element Method in 2D which leads to significant computational advantages over the 3D model. The methodology is validated for an RM (rectangular modulus ferrite core working in the linear and the saturation regions. Excellent agreement is found between the experimental data and the computational results.

  9. Transverse Crack Modeling and Validation in Rotor Systems Including Thermal Effects

    Directory of Open Access Journals (Sweden)

    N. Bachschmid

    2004-01-01

    Full Text Available In this article, a model is described that allows one to simulate the static behavior of a transversal crack in a horizontal rotor, under the action of the weight and other possible static loads and the dynamical behavior of the rotating cracked shaft. The crack “breaths,” i.e., the mechanism of opening and closing of the crack, is ruled by the stress acting on the cracked section due to the external loads; in a rotor the stress is time-depending with a period equal to the period of rotation, thus the crack “periodically breaths.” An original simplified model is described that allows cracks of different shape to be modeled and thermal stresses to be taken into account, since they may influence the opening and closing mechanism. The proposed method has been validated using two criteria. Firstly, the crack “breathing” mechanism, simulated with the model, has been compared with the results obtained by a nonlinear 3-D FEM calculation and a good agreement in the results has been observed. Secondly, the proposed model allows the development of the equivalent cracked beam. The results of this model are compared with those obtained by the above-mentioned 3-D FEM. There is a good agreement in the results, of this case as well.

  10. Finding practical phenomenological models that include both photoresist behavior and etch process effects

    Science.gov (United States)

    Jung, Sunwook; Do, Thuy; Sturtevant, John

    2015-03-01

    For more than five decades, the semiconductor industry has overcome technology challenges with innovative ideas that have continued to enable Moore's Law. It is clear that multi-patterning lithography is vital for 20nm half pitch using 193i. Multi-patterning exposure sequences and pattern multiplication processes can create complicated tolerance accounting due to the variability associated with the component processes. It is essential to ensure good predictive accuracy of compact etch models used in multipatterning simulation. New modelforms have been developed to account for etch bias behavior at 20 nm and below. The new modeling components show good results in terms of global fitness and some improved predication capability for specific features. We've also investigated a new methodology to make the etch model aware of 3D resist profiles.

  11. The Bauschinger Effect in Autofrettaged Tubes- A Comparison of Models Including the ASME Code

    National Research Council Canada - National Science Library

    Parker, Anthony

    1998-01-01

    .... For many years workers have acknowledged the probable influence of the Bauschinger effect which serves to reduce the yield strength in compression as a result of prior tensile plastic overload...

  12. Modelling the Colour of Strawberry Spread During Storage, Including Effects of Technical Variations

    Directory of Open Access Journals (Sweden)

    Kadivec Mirta

    2016-12-01

    Full Text Available The colour of freshly processed strawberry spread changes relatively rapidly from a bright red to a dull red, which then makes its appearance generally less acceptable for consumers. The colours of strawberry spreads following several processing conditions were measured under different storage conditions. Additional sugar and colorant had only slight effects on the colour decay, while exclusion of oxygen and daylight did not affect this process. The only condition that clearly maintained the freshly processed appearance was storage at 4°C. Hexagonal bottles were filled with the strawberry spreads and their colour was repeatedly measured at the six sides of the bottles, using a Minolta chroma meter. Data were analysed using non-linear indexed regression analysis based on a logistic function for the three colour aspect of a*, b* and L*. This technology allowed the determination of the variation in these data in terms of improved reliability (R2adj, >90%. It also allowed better interpretation of the processes involved. All variations in the data could be attributed to technical variation.

  13. Nonlocal continuum-based modeling of breathing mode of nanowires including surface stress and surface inertia effects

    International Nuclear Information System (INIS)

    Ghavanloo, Esmaeal; Fazelzadeh, S. Ahmad; Rafii-Tabar, Hashem

    2014-01-01

    Nonlocal and surface effects significantly influence the mechanical response of nanomaterials and nanostructures. In this work, the breathing mode of a circular nanowire is studied on the basis of the nonlocal continuum model. Both the surface elastic properties and surface inertia effect are included. Nanowires can be modeled as long cylindrical solid objects. The classical model is reformulated using the nonlocal differential constitutive relations of Eringen and Gurtin–Murdoch surface continuum elasticity formalism. A new frequency equation for the breathing mode of nanowires, including small scale effect, surface stress and surface inertia is presented by employing the Bessel functions. Numerical results are computed, and are compared to confirm the validity and accuracy of the proposed method. Furthermore, the model is used to elucidate the effect of nonlocal parameter, the surface stress, the surface inertia and the nanowire orientation on the breathing mode of several types of nanowires with size ranging from 0.5 to 4 nm. Our results reveal that the combined surface and small scale effects are significant for nanowires with diameter smaller than 4 nm.

  14. Nonlocal continuum-based modeling of breathing mode of nanowires including surface stress and surface inertia effects

    Science.gov (United States)

    Ghavanloo, Esmaeal; Fazelzadeh, S. Ahmad; Rafii-Tabar, Hashem

    2014-05-01

    Nonlocal and surface effects significantly influence the mechanical response of nanomaterials and nanostructures. In this work, the breathing mode of a circular nanowire is studied on the basis of the nonlocal continuum model. Both the surface elastic properties and surface inertia effect are included. Nanowires can be modeled as long cylindrical solid objects. The classical model is reformulated using the nonlocal differential constitutive relations of Eringen and Gurtin-Murdoch surface continuum elasticity formalism. A new frequency equation for the breathing mode of nanowires, including small scale effect, surface stress and surface inertia is presented by employing the Bessel functions. Numerical results are computed, and are compared to confirm the validity and accuracy of the proposed method. Furthermore, the model is used to elucidate the effect of nonlocal parameter, the surface stress, the surface inertia and the nanowire orientation on the breathing mode of several types of nanowires with size ranging from 0.5 to 4 nm. Our results reveal that the combined surface and small scale effects are significant for nanowires with diameter smaller than 4 nm.

  15. Tracer experiment data sets for the verification of local and meso-scale atmospheric dispersion models including topographic effects

    International Nuclear Information System (INIS)

    Sartori, E.; Schuler, W.

    1992-01-01

    Software and data for nuclear energy applications are acquired, tested and distributed by several information centres; in particular, relevant computer codes are distributed internationally by the OECD/NEA Data Bank (France) and by ESTSC and EPIC/RSIC (United States). This activity is coordinated among the centres and is extended outside the OECD area through an arrangement with the IAEA. This article proposes more specifically a scheme for acquiring, storing and distributing atmospheric tracer experiment data (ATE) required for verification of atmospheric dispersion models especially the most advanced ones including topographic effects and specific to the local and meso-scale. These well documented data sets will form a valuable complement to the set of atmospheric dispersion computer codes distributed internationally. Modellers will be able to gain confidence in the predictive power of their models or to verify their modelling skills. (au)

  16. Modelling the effect of acoustic waves on the thermodynamics and kinetics of phase transformation in a solution: Including mass transportation

    Science.gov (United States)

    Haqshenas, S. R.; Ford, I. J.; Saffari, N.

    2018-01-01

    Effects of acoustic waves on a phase transformation in a metastable phase were investigated in our previous work [S. R. Haqshenas, I. J. Ford, and N. Saffari, "Modelling the effect of acoustic waves on nucleation," J. Chem. Phys. 145, 024315 (2016)]. We developed a non-equimolar dividing surface cluster model and employed it to determine the thermodynamics and kinetics of crystallisation induced by an acoustic field in a mass-conserved system. In the present work, we developed a master equation based on a hybrid Szilard-Fokker-Planck model, which accounts for mass transportation due to acoustic waves. This model can determine the kinetics of nucleation and the early stage of growth of clusters including the Ostwald ripening phenomenon. It was solved numerically to calculate the kinetics of an isothermal sonocrystallisation process in a system with mass transportation. The simulation results show that the effect of mass transportation for different excitations depends on the waveform as well as the imposed boundary conditions and tends to be noticeable in the case of shock waves. The derivations are generic and can be used with any acoustic source and waveform.

  17. Including the effects of elastic compressibility and volume changes in geodynamical modeling of crust-lithosphere-mantle deformation

    Science.gov (United States)

    de Monserrat, Albert; Morgan, Jason P.

    2016-04-01

    Materials in Earth's interior are exposed to thermomechanical (e.g. variations in stress/pressure and temperature) and chemical (e.g. phase changes, serpentinization, melting) processes that are associated with volume changes. Most geodynamical codes assume the incompressible Boussinesq approximation, where changes in density due to temperature or phase change effect buoyancy, yet volumetric changes are not allowed, and mass is not locally conserved. Elastic stresses induced by volume changes due to thermal expansion, serpentinization, and melt intrusion should cause 'cold' rocks to brittlely fail at ~1% strain. When failure/yielding is an important rheological feature, we think it plausible that volume-change-linked stresses may have a significant influence on the localization of deformation. Here we discuss a new Lagrangian formulation for "elasto-compressible -visco-plastic" flow. In this formulation, the continuity equation has been generalised from a Boussinesq incompressible formulation to include recoverable, elastic, volumetric deformations linked to the local state of mean compressive stress. This formulation differs from the 'anelastic approximation' used in compressible viscous flow in that pressure- and temperature- dependent volume changes are treated as elastic deformation for a given pressure, temperature, and composition/phase. This leads to a visco-elasto-plastic formulation that can model the effects of thermal stresses, pressure-dependent volume changes, and local phase changes. We use a modified version of the (Miliman-based) FEM code M2TRI to run a set of numerical experiments for benchmarking purposes. Three benchmarks are being used to assess the accuracy of this formulation: (1) model the effects on density of a compressible mantle under the influence of gravity; (2) model the deflection of a visco-elastic beam under the influence of gravity, and its recovery when gravitational loading is artificially removed; (3) Modelling the stresses

  18. Finite Element Modeling and Analysis of Nonlinear Impact and Frictional Motion Responses Including Fluid—Structure Coupling Effects

    Directory of Open Access Journals (Sweden)

    Yong Zhao

    1997-01-01

    Full Text Available A nonlinear three dimensional (3D single rack model and a nonlinear 3D whole pool multi-rack model are developed for the spent fuel storage racks of a nuclear power plant (NPP to determine impacts and frictional motion responses when subjected to 3D excitations from the supporting building floor. The submerged free standing rack system and surrounding water are coupled due to hydrodynamic fluid-structure interaction (FSI using potential theory. The models developed have features that allow consideration of geometric and material nonlinearities including (1 the impacts of fuel assemblies to rack cells, a rack to adjacent racks or pool walls, and rack support legs to the pool floor; (2 the hydrodynamic coupling of fuel assemblies with their storing racks, and of a rack with adjacent racks, pool walls, and the pool floor; and (3 the dynamic motion behavior of rocking, twisting, and frictional sliding of rack modules. Using these models 3D nonlinear time history dynamic analyses are performed per the U.S. Nuclear Regulatory Commission (USNRC criteria. Since few such modeling, analyses, and results using both the 3D single and whole pool multiple rack models are available in the literature, this paper emphasizes description of modeling and analysis techniques using the SOLVIA general purpose nonlinear finite element code. Typical response results with different Coulomb friction coefficients are presented and discussed.

  19. Including the effects of filamentous bulking sludge during the simulation of wastewater treatment plants using a risk assessment model

    DEFF Research Database (Denmark)

    Flores Alsina, Xavier; Comas, J.; Rodriquez-Roda, I.

    2009-01-01

    pollution removal efficiency is observed. Also, a scenario analysis is conducted to examine i) the influence of sludge retention time (SRT), the external recirculation flow rate (Qr) and the air flow rate in the bioreactor (modelled as kLa) as factors promoting bulking sludge, and ii) the effect...

  20. Fatigue Behavior and Modeling of Additively Manufactured Ti-6Al-4V Including Interlayer Time Interval Effects

    Science.gov (United States)

    Torries, Brian; Shamsaei, Nima

    2017-12-01

    The effects of different cooling rates, as achieved by varying the interlayer time interval, on the fatigue behavior of additively manufactured Ti-6Al-4V specimens were investigated and modeled via a microstructure-sensitive fatigue model. Comparisons are made between two sets of specimens fabricated via Laser Engineered Net Shaping (LENS™), with variance in interlayer time interval accomplished by depositing either one or two specimens per print operation. Fully reversed, strain-controlled fatigue tests were conducted, with fractography following specimen failure. A microstructure-sensitive fatigue model was calibrated to model the fatigue behavior of both sets of specimens and was found to be capable of correctly predicting the longer fatigue lives of the single-built specimens and the reduced scatter of the double-built specimens; all data points fell within the predicted upper and lower bounds of fatigue life. The time interval effects and the ability to be modeled are important to consider when producing test specimens that are smaller than the production part (i.e., property-performance relationships).

  1. Modeling the Nonlinear, Strain Rate Dependent Deformation of Woven Ceramic Matrix Composites With Hydrostatic Stress Effects Included

    Science.gov (United States)

    Goldberg, Robert K.; Carney, Kelly S.

    2004-01-01

    An analysis method based on a deformation (as opposed to damage) approach has been developed to model the strain rate dependent, nonlinear deformation of woven ceramic matrix composites with a plain weave fiber architecture. In the developed model, the differences in the tension and compression response have also been considered. State variable based viscoplastic equations originally developed for metals have been modified to analyze the ceramic matrix composites. To account for the tension/compression asymmetry in the material, the effective stress and effective inelastic strain definitions have been modified. The equations have also been modified to account for the fact that in an orthotropic composite the in-plane shear stiffness is independent of the stiffness in the normal directions. The developed equations have been implemented into a commercially available transient dynamic finite element code, LS-DYNA, through the use of user defined subroutines (UMATs). The tensile, compressive, and shear deformation of a representative plain weave woven ceramic matrix composite are computed and compared to experimental results. The computed values correlate well to the experimental data, demonstrating the ability of the model to accurately compute the deformation response of woven ceramic matrix composites.

  2. Modeling the Nonlinear, Strain Rate Dependent Deformation of Shuttle Leading Edge Materials with Hydrostatic Stress Effects Included

    Science.gov (United States)

    Goldberg, Robert K.; Carney, Kelly S.

    2004-01-01

    An analysis method based on a deformation (as opposed to damage) approach has been developed to model the strain rate dependent, nonlinear deformation of woven ceramic matrix composites, such as the Reinforced Carbon Carbon (RCC) material used on the leading edges of the Space Shuttle. In the developed model, the differences in the tension and compression deformation behaviors have also been accounted for. State variable viscoplastic equations originally developed for metals have been modified to analyze the ceramic matrix composites. To account for the tension/compression asymmetry in the material, the effective stress and effective inelastic strain definitions have been modified. The equations have also been modified to account for the fact that in an orthotropic composite the in-plane shear response is independent of the stiffness in the normal directions. The developed equations have been implemented into LS-DYNA through the use of user defined subroutines (UMATs). Several sample qualitative calculations have been conducted, which demonstrate the ability of the model to qualitatively capture the features of the deformation response present in woven ceramic matrix composites.

  3. SEEPAGE MODEL FOR PA INCLUDING DRIFT COLLAPSE

    International Nuclear Information System (INIS)

    C. Tsang

    2004-01-01

    The purpose of this report is to document the predictions and analyses performed using the seepage model for performance assessment (SMPA) for both the Topopah Spring middle nonlithophysal (Tptpmn) and lower lithophysal (Tptpll) lithostratigraphic units at Yucca Mountain, Nevada. Look-up tables of seepage flow rates into a drift (and their uncertainty) are generated by performing numerical simulations with the seepage model for many combinations of the three most important seepage-relevant parameters: the fracture permeability, the capillary-strength parameter 1/a, and the percolation flux. The percolation flux values chosen take into account flow focusing effects, which are evaluated based on a flow-focusing model. Moreover, multiple realizations of the underlying stochastic permeability field are conducted. Selected sensitivity studies are performed, including the effects of an alternative drift geometry representing a partially collapsed drift from an independent drift-degradation analysis (BSC 2004 [DIRS 166107]). The intended purpose of the seepage model is to provide results of drift-scale seepage rates under a series of parameters and scenarios in support of the Total System Performance Assessment for License Application (TSPA-LA). The SMPA is intended for the evaluation of drift-scale seepage rates under the full range of parameter values for three parameters found to be key (fracture permeability, the van Genuchten 1/a parameter, and percolation flux) and drift degradation shape scenarios in support of the TSPA-LA during the period of compliance for postclosure performance [Technical Work Plan for: Performance Assessment Unsaturated Zone (BSC 2002 [DIRS 160819], Section I-4-2-1)]. The flow-focusing model in the Topopah Spring welded (TSw) unit is intended to provide an estimate of flow focusing factors (FFFs) that (1) bridge the gap between the mountain-scale and drift-scale models, and (2) account for variability in local percolation flux due to

  4. A depth-averaged debris-flow model that includes the effects of evolving dilatancy. I. physical basis

    Science.gov (United States)

    Iverson, Richard M.; George, David L.

    2014-01-01

    To simulate debris-flow behaviour from initiation to deposition, we derive a depth-averaged, two-phase model that combines concepts of critical-state soil mechanics, grain-flow mechanics and fluid mechanics. The model's balance equations describe coupled evolution of the solid volume fraction, m, basal pore-fluid pressure, flow thickness and two components of flow velocity. Basal friction is evaluated using a generalized Coulomb rule, and fluid motion is evaluated in a frame of reference that translates with the velocity of the granular phase, vs. Source terms in each of the depth-averaged balance equations account for the influence of the granular dilation rate, defined as the depth integral of ∇⋅vs. Calculation of the dilation rate involves the effects of an elastic compressibility and an inelastic dilatancy angle proportional to m−meq, where meq is the value of m in equilibrium with the ambient stress state and flow rate. Normalization of the model equations shows that predicted debris-flow behaviour depends principally on the initial value of m−meq and on the ratio of two fundamental timescales. One of these timescales governs downslope debris-flow motion, and the other governs pore-pressure relaxation that modifies Coulomb friction and regulates evolution of m. A companion paper presents a suite of model predictions and tests.

  5. A two-dimensional model of the pressing section of a paper machine including dynamic capillary effects

    KAUST Repository

    Iliev, Oleg P.

    2013-05-15

    Paper production is a problem with significant importance for society; it is also a challenging topic for scientific investigation. This study is concerned with the simulation of the pressing section of a paper machine. A two-dimensional model is developed to account for the water flow within the pressing zone. A Richards-type equation is used to describe the flow in the unsaturated zone. The dynamic capillary pressure-saturation relation is adopted for the paper production process. The mathematical model accounts for the coexistence of saturated and unsaturated zones in a multilayer computational domain. The discretization is performed by the MPFA-O method. Numerical experiments are carried out for parameters that are typical of the production process. The static and dynamic capillary pressure-saturation relations are tested to evaluate the influence of the dynamic capillary effect. © 2013 Springer Science+Business Media Dordrecht.

  6. The electric field in capacitively coupled RF discharges: a smooth step model that includes thermal and dynamic effects

    Science.gov (United States)

    Brinkmann, Ralf Peter

    2015-12-01

    The electric field in radio-frequency driven capacitively coupled plasmas (RF-CCP) is studied, taking thermal (finite electron temperature) and dynamic (finite electron mass) effects into account. Two dimensionless numbers are introduced, the ratios ε ={λ\\text{D}}/l of the electron Debye length {λ\\text{D}} to the minimum plasma gradient length l (typically the sheath thickness) and η ={ω\\text{RF}}/{ω\\text{pe}} of the RF frequency {ω\\text{RF}} to the electron plasma frequency {ω\\text{pe}} . Assuming both numbers small but finite, an asymptotic expansion of an electron fluid model is carried out up to quadratic order inclusively. An expression for the electric field is obtained which yields (i) the space charge field in the sheath, (ii) the generalized Ohmic and ambipolar field in the plasma, and (iii) a smooth interpolation for the transition in between. The new expression is a direct generalization of the Advanced Algebraic Approximation (AAA) proposed by the same author (2009 J. Phys. D: Appl. Phys. 42 194009), which can be recovered for η \\to 0 , and of the established Step Model (SM) by Godyak (1976 Sov. J. Plasma Phys. 2 78), which corresponds to the simultaneous limits η \\to 0 , ε \\to 0 . A comparison of the hereby proposed Smooth Step Model (SSM) with a numerical solution of the full dynamic problem proves very satisfactory.

  7. Model of Organic Solar Cell Photocurrent Including the Effect of Charge Accumulation at Interfaces and Non-Uniform Carrier Generation

    DEFF Research Database (Denmark)

    Torto, Lorenzo; Cester, Andrea; Rizzo, Antonio

    2017-01-01

    We developed an improved model to fit the photocurrent density versus voltage in organic solar cells. The model has been validated by fitting data from P3HT:PCBM solar cells. Our model quantitatively accounts for the band bending near the electrodes caused by charge accumulation in the active layer...

  8. Determining surface wave attenuation by modeling surface wave amplitudes including finite-frequency focusing and defocusing effects

    Science.gov (United States)

    Ma, Z.; Masters, G.

    2011-12-01

    We have developed a technique that uses cluster analysis method to efficiently measure Rayleigh wave phase and amplitude anomalies. Amplitude anomaly measurements have been made on the vertical components of all permanent stations recording LHZ data from IRIS. We currently consider earthquakes with Ms>5.5 between 1990 and 2004 and correct for source phase and magnitude according to the CMT. This technique leads to a large set of amplitude measurements at 7mHz, 10mHz, 15mHz and 20mHz. We discard data with erroneously large amplitude anomalies (|dlnA|>1) and inconsistent instrument responses and we only use earthquakes recorded by more than 30 stations. Out of about 250000 raw measurements for each frequency, about 140000 measurements are retained for inverting for attenuation structure. Similar to Dalton and Ekstrom (2006), phase and amplitude data are inverted together for phase velocity maps, attenuation maps, and source and receiver terms. However, we use the 2D finite frequency amplitude kernel of Zhou et al, (2004) to model the focusing-defocusing effects. Ray theory, which has been used to date, gives amplitude anomaly predictions which depend strongly on short wavelength structure and so are very sensitive to how phase velocity maps are smoothed. Our resulting attenuation maps show structures correlating well with surface tectonics, with high attenuation in regions of ridges, back-arc basins and western North America, and low attenuation in stable continental shields. The success of getting reasonable attenuation structures demonstrates the feasibility of applying 2D finite frequency amplitude kernel to real data.

  9. Numerical modeling of AA2024-T3 friction stir welding process for residual stress evaluation, including softening effects

    DEFF Research Database (Denmark)

    Sonne, Mads Rostgaard; Carlone, Pierpaolo; Palazzo, Gaetano S.

    2014-01-01

    In the present paper, a numerical finite element model of the precipitation hardenable AA2024-T3 aluminum alloy, consisting of a heat transfer analysis based on the Thermal Pseudo Mechanical model for heat generation, and a sequentially coupled quasi-static stress analysis is proposed. Metallurgi......In the present paper, a numerical finite element model of the precipitation hardenable AA2024-T3 aluminum alloy, consisting of a heat transfer analysis based on the Thermal Pseudo Mechanical model for heat generation, and a sequentially coupled quasi-static stress analysis is proposed...

  10. Modeling of damage in ductile cast iron – The effect of including plasticity in the graphite noduless

    DEFF Research Database (Denmark)

    Andriollo, Tito; Thorborg, Jesper; Tiedje, Niels Skat

    2015-01-01

    In the present paper a micro-mechanical model for investigating the stress-strain relation of ductile cast iron subjected to simple loading conditions is presented. The model is based on a unit cell containing a single spherical graphite nodule embedded in a uniform ferritic matrix, under the ass...

  11. Stress and Fatigue Life Modeling of Cannon Breech Closures Including Effects of Material Strength and Residual Stress

    National Research Council Canada - National Science Library

    Underwood, John

    2000-01-01

    ...; overload residual stress. Modeling of applied and residual stresses at the location of the fatigue failure site is performed by elastic-plastic finite element analysis using ABAQUS and by solid...

  12. Plasmonic modes in nanowire dimers: A study based on the hydrodynamic Drude model including nonlocal and nonlinear effects

    Science.gov (United States)

    Moeferdt, Matthias; Kiel, Thomas; Sproll, Tobias; Intravaia, Francesco; Busch, Kurt

    2018-02-01

    A combined analytical and numerical study of the modes in two distinct plasmonic nanowire systems is presented. The computations are based on a discontinuous Galerkin time-domain approach, and a fully nonlinear and nonlocal hydrodynamic Drude model for the metal is utilized. In the linear regime, these computations demonstrate the strong influence of nonlocality on the field distributions as well as on the scattering and absorption spectra. Based on these results, second-harmonic-generation efficiencies are computed over a frequency range that covers all relevant modes of the linear spectra. In order to interpret the physical mechanisms that lead to corresponding field distributions, the associated linear quasielectrostatic problem is solved analytically via conformal transformation techniques. This provides an intuitive classification of the linear excitations of the systems that is then applied to the full Maxwell case. Based on this classification, group theory facilitates the determination of the selection rules for the efficient excitation of modes in both the linear and nonlinear regimes. This leads to significantly enhanced second-harmonic generation via judiciously exploiting the system symmetries. These results regarding the mode structure and second-harmonic generation are of direct relevance to other nanoantenna systems.

  13. Seepage Model for PA Including Drift Collapse

    International Nuclear Information System (INIS)

    Li, G.; Tsang, C.

    2000-01-01

    The purpose of this Analysis/Model Report (AMR) is to document the predictions and analysis performed using the Seepage Model for Performance Assessment (PA) and the Disturbed Drift Seepage Submodel for both the Topopah Spring middle nonlithophysal and lower lithophysal lithostratigraphic units at Yucca Mountain. These results will be used by PA to develop the probability distribution of water seepage into waste-emplacement drifts at Yucca Mountain, Nevada, as part of the evaluation of the long term performance of the potential repository. This AMR is in accordance with the ''Technical Work Plan for Unsaturated Zone (UZ) Flow and Transport Process Model Report'' (CRWMS M andO 2000 [153447]). This purpose is accomplished by performing numerical simulations with stochastic representations of hydrological properties, using the Seepage Model for PA, and evaluating the effects of an alternative drift geometry representing a partially collapsed drift using the Disturbed Drift Seepage Submodel. Seepage of water into waste-emplacement drifts is considered one of the principal factors having the greatest impact of long-term safety of the repository system (CRWMS M andO 2000 [153225], Table 4-1). This AMR supports the analysis and simulation that are used by PA to develop the probability distribution of water seepage into drift, and is therefore a model of primary (Level 1) importance (AP-3.15Q, ''Managing Technical Product Inputs''). The intended purpose of the Seepage Model for PA is to support: (1) PA; (2) Abstraction of Drift-Scale Seepage; and (3) Unsaturated Zone (UZ) Flow and Transport Process Model Report (PMR). Seepage into drifts is evaluated by applying numerical models with stochastic representations of hydrological properties and performing flow simulations with multiple realizations of the permeability field around the drift. The Seepage Model for PA uses the distribution of permeabilities derived from air injection testing in niches and in the cross drift to

  14. Seepage Model for PA Including Dift Collapse

    Energy Technology Data Exchange (ETDEWEB)

    G. Li; C. Tsang

    2000-12-20

    The purpose of this Analysis/Model Report (AMR) is to document the predictions and analysis performed using the Seepage Model for Performance Assessment (PA) and the Disturbed Drift Seepage Submodel for both the Topopah Spring middle nonlithophysal and lower lithophysal lithostratigraphic units at Yucca Mountain. These results will be used by PA to develop the probability distribution of water seepage into waste-emplacement drifts at Yucca Mountain, Nevada, as part of the evaluation of the long term performance of the potential repository. This AMR is in accordance with the ''Technical Work Plan for Unsaturated Zone (UZ) Flow and Transport Process Model Report'' (CRWMS M&O 2000 [153447]). This purpose is accomplished by performing numerical simulations with stochastic representations of hydrological properties, using the Seepage Model for PA, and evaluating the effects of an alternative drift geometry representing a partially collapsed drift using the Disturbed Drift Seepage Submodel. Seepage of water into waste-emplacement drifts is considered one of the principal factors having the greatest impact of long-term safety of the repository system (CRWMS M&O 2000 [153225], Table 4-1). This AMR supports the analysis and simulation that are used by PA to develop the probability distribution of water seepage into drift, and is therefore a model of primary (Level 1) importance (AP-3.15Q, ''Managing Technical Product Inputs''). The intended purpose of the Seepage Model for PA is to support: (1) PA; (2) Abstraction of Drift-Scale Seepage; and (3) Unsaturated Zone (UZ) Flow and Transport Process Model Report (PMR). Seepage into drifts is evaluated by applying numerical models with stochastic representations of hydrological properties and performing flow simulations with multiple realizations of the permeability field around the drift. The Seepage Model for PA uses the distribution of permeabilities derived from air injection testing in

  15. An Integrated Biochemistry Laboratory, Including Molecular Modeling

    Science.gov (United States)

    Hall, Adele J. Wolfson Mona L.; Branham, Thomas R.

    1996-11-01

    ) experience with methods of protein purification; (iii) incorporation of appropriate controls into experiments; (iv) use of basic statistics in data analysis; (v) writing papers and grant proposals in accepted scientific style; (vi) peer review; (vii) oral presentation of results and proposals; and (viii) introduction to molecular modeling. Figure 1 illustrates the modular nature of the lab curriculum. Elements from each of the exercises can be separated and treated as stand-alone exercises, or combined into short or long projects. We have been able to offer the opportunity to use sophisticated molecular modeling in the final module through funding from an NSF-ILI grant. However, many of the benefits of the research proposal can be achieved with other computer programs, or even by literature survey alone. Figure 1.Design of project-based biochemistry laboratory. Modules (projects, or portions of projects) are indicated as boxes. Each of these can be treated independently, or used as part of a larger project. Solid lines indicate some suggested paths from one module to the next. The skills and knowledge required for protein purification and design are developed in three units: (i) an introduction to critical assays needed to monitor degree of purification, including an evaluation of assay parameters; (ii) partial purification by ion-exchange techniques; and (iii) preparation of a grant proposal on protein design by mutagenesis. Brief descriptions of each of these units follow, with experimental details of each project at the end of this paper. Assays for Lysozyme Activity and Protein Concentration (4 weeks) The assays mastered during the first unit are a necessary tool for determining the purity of the enzyme during the second unit on purification by ion exchange. These assays allow an introduction to the concept of specific activity (units of enzyme activity per milligram of total protein) as a measure of purity. In this first sequence, students learn a turbidimetric assay

  16. Grand unified models including extra Z bosons

    International Nuclear Information System (INIS)

    Li Tiezhong

    1989-01-01

    The grand unified theories (GUT) of the simple Lie groups including extra Z bosons are discussed. Under authors's hypothesis there are only SU 5+m SO 6+4n and E 6 groups. The general discussion of SU 5+m is given, then the SU 6 and SU 7 are considered. In SU 6 the 15+6 * +6 * fermion representations are used, which are not same as others in fermion content, Yukawa coupling and broken scales. A conception of clans of particles, which are not families, is suggested. These clans consist of extra Z bosons and the corresponding fermions of the scale. The all of fermions in the clans are down quarks except for the standard model which consists of Z bosons and 15 fermions, therefore, the spectrum of the hadrons which are composed of these down quarks are different from hadrons at present

  17. Estimates of effective elastic thickness of oceanic lithosphere using model including surface and subsurface loads and effective elastic thickness of subduction zones

    Science.gov (United States)

    Yang, A.; Yongtao, F.

    2016-12-01

    The effective elastic thickness (Te) is an important parameter that characterizes the long term strength of the lithosphere, which has great significance on understanding the mechanical properties and evolution of the lithosphere. In contrast with many controversies regarding elastic thickness of continent lithosphere, the Te of oceanic lithosphere is thought to be in a simple way that is dependent on the age of the plate. However, rescent studies show that there is no simple relationship between Te and age at time of loading for both seamounts and subduction zones. As subsurface loading is very importand and has large influence in the estimate of Te for continent lithosphere, and many oceanic features such as subduction zones also have considerable subsurface loading. We introduce the method to estimate the effective elastic thickness of oceanic lithosphere using model including surface and subsurface loads by using free-air gravity anomaly and bathymetric data, together with a moving window admittance technique (MWAT). We use the multitaper spectral estimation method to calculate the power spectral density. Through tests with synthetic subduction zone like bathymetry and gravity data show that the Te can be recovered in an accurance similar to that in the continent and there is also a trade-off between spatial resolution and variance for different window sizes. We estimate Te of many subduction zones (Peru-Chile trench, Middle America trench, Caribbean trench, Kuril-Japan trench, Mariana trench, Tonga trench, Java trench, Ryukyu-Philippine trench) with an age range of 0-160 Myr to reassess the relationship between elastic thickness and the age of the lithosphere at the time of loading. The results do not show a simple relationship between Te and age.

  18. DEVELOPMENT OF A HYDRODYNAMIC MODEL OF A HYDROCYCLONE INCLUDING THE SIMULATION OF AIR-CORE EFFECT, USING THE FINITE VOLUME METHOD

    Directory of Open Access Journals (Sweden)

    Gabriel Felipe Aguilera

    2014-07-01

    Full Text Available The hydrocyclone is one of the most used classification equipment in industry, particularly in mineral processing. Maybe its main characteristic is to be a hydrodynamic separation equipment, whereby it has a high production capability and different levels of efficiency are depending on the geometrical configuration, operational parameters and the type of material to be processed. Nevertheless, there are a few successful studies regarding the modelling and simulation of its hydrodynamic principles, because the flow behavior inside is quite complex. Most of the current models are empirical and they are not applicable to all cases and types of minerals. One of the most important problems to be solved, besides the cut size and the effect of the physical properties of the particles, is the distribution of the flow inside the hydrocyclone, because if the work of the equipment is at low slurry densities, very clear for small hydrocyclones, its mechanic behavior is a consequence of the kind of liquid used as continuous phase, being water the most common liquid. This work shows the modelling and simulation of the hydrodynamic behavior of a suspension inside a hydrocyclone, including the air core effect, through the use of finite differences method. For the developing of the model, the Reynolds Stress Model (RSM for the evaluation of turbulence, and the Volume of Fluid (VOF to study the interaction between water and air were used. Finally, the model shows to be significant for experimental data, and for different conditions of an industrial plant.

  19. Vibration of Piezoelectric Nanowires Including Surface Effects

    Directory of Open Access Journals (Sweden)

    R. Ansari

    2014-04-01

    Full Text Available In this paper, surface and piezoelectric effects on the vibration behavior of nanowires (NWs are investigated by using a Timoshenko beam model. The electric field equations and the governing equations of motion for the piezoelectric NWs are derived with the consideration of surface effects. By the exact solution of the governing equations, an expression for the natural frequencies of NWs with simply-supported boundary conditions is obtained. The effects of piezoelectricity and surface effects on the vibrational behavior of Timoshenko NWs are graphically illustrated. A comparison is also made between the predictions of Timoshenko beam model and those of its Euler-Bernoulli counterpart. Additionally, the present results are validated through comparison with the available data in the literature.

  20. BIOLOGIC AND ECONOMIC EFFECTS OF INCLUDING DIFFERENT ...

    African Journals Online (AJOL)

    The biologic and economic effects of including three agro-industrial by-products as ingredients in turkey poult diets were investigated using 48 turkey poults in a completely randomised design experiment. Diets were formulated to contain the three by-products – wheat offal, rice husk and palm kernel meal, each at 20% level ...

  1. Development of nonperturbative nonlinear optics models including effects of high order nonlinearities and of free electron plasma: Maxwell-Schrödinger equations coupled with evolution equations for polarization effects, and the SFA-like nonlinear optics model

    Science.gov (United States)

    Lorin, E.; Lytova, M.; Memarian, A.; Bandrauk, A. D.

    2015-03-01

    This paper is dedicated to the exploration of non-conventional nonlinear optics models for intense and short electromagnetic fields propagating in a gas. When an intense field interacts with a gas, usual nonlinear optics models, such as cubic nonlinear Maxwell, wave and Schrödinger equations, derived by perturbation theory may become inaccurate or even irrelevant. As a consequence, and to include in particular the effect of free electrons generated by laser-molecule interaction, several heuristic models, such as UPPE, HOKE models, etc, coupled with Drude-like models [1, 2], were derived. The goal of this paper is to present alternative approaches based on non-heuristic principles. This work is in particular motivated by the on-going debate in the filamentation community, about the effect of high order nonlinearities versus plasma effects due to free electrons, in pulse defocusing occurring in laser filaments [3-9]. The motivation of our work goes beyond filamentation modeling, and is more generally related to the interaction of any external intense and (short) pulse with a gas. In this paper, two different strategies are developed. The first one is based on the derivation of an evolution equation on the polarization, in order to determine the response of the medium (polarization) subject to a short and intense electromagnetic field. Then, we derive a combined semi-heuristic model, based on Lewenstein’s strong field approximation model and the usual perturbative modeling in nonlinear optics. The proposed model allows for inclusion of high order nonlinearities as well as free electron plasma effects.

  2. Simple suggestions for including vertical physics in oil spill models

    International Nuclear Information System (INIS)

    D'Asaro, Eric; University of Washington, Seatle, WA

    2001-01-01

    Current models of oil spills include no vertical physics. They neglect the effect of vertical water motions on the transport and concentration of floating oil. Some simple ways to introduce vertical physics are suggested here. The major suggestion is to routinely measure the density stratification of the upper ocean during oil spills in order to develop a database on the effect of stratification. (Author)

  3. Bofu-tsu-shosan, an oriental herbal medicine, exerts a combinatorial favorable metabolic modulation including antihypertensive effect on a mouse model of human metabolic disorders with visceral obesity.

    Directory of Open Access Journals (Sweden)

    Kengo Azushima

    Full Text Available Accumulating evidence indicates that metabolic dysfunction with visceral obesity is a major medical problem associated with the development of hypertension, type 2 diabetes (T2DM and dyslipidemia, and ultimately severe cardiovascular and renal disease. Therefore, an effective anti-obesity treatment with a concomitant improvement in metabolic profile is important for the treatment of metabolic dysfunction with visceral obesity. Bofu-tsu-shosan (BOF is one of oriental herbal medicine and is clinically available to treat obesity in Japan. Although BOF is a candidate as a novel therapeutic strategy to improve metabolic dysfunction with obesity, the mechanism of its beneficial effect is not fully elucidated. Here, we investigated mechanism of therapeutic effects of BOF on KKAy mice, a model of human metabolic disorders with obesity. Chronic treatment of KKAy mice with BOF persistently decreased food intake, body weight gain, low-density lipoprotein cholesterol and systolic blood pressure. In addition, both tissue weight and cell size of white adipose tissue (WAT were decreased, with concomitant increases in the expression of adiponectin and peroxisome proliferator-activated receptors genes in WAT as well as the circulating adiponectin level by BOF treatment. Furthermore, gene expression of uncoupling protein-1, a thermogenesis factor, in brown adipose tissue and rectal temperature were both elevated by BOF. Intriguingly, plasma acylated-ghrelin, an active form of orexigenic hormone, and short-term food intake were significantly decreased by single bolus administration of BOF. These results indicate that BOF exerts a combinatorial favorable metabolic modulation including antihypertensive effect, at least partially, via its beneficial effect on adipose tissue function and its appetite-inhibitory property through suppression on the ghrelin system.

  4. Health and economic benefits of reducing sugar intake in the USA, including effects via non-alcoholic fatty liver disease: a microsimulation model

    Science.gov (United States)

    Vreman, Rick A; Goodell, Alex J; Rodriguez, Luis A; Porco, Travis C; Lustig, Robert H; Kahn, James G

    2017-01-01

    Objectives Excessive consumption of added sugars in the human diet has been associated with obesity, type 2 diabetes (T2D), coronary heart disease (CHD) and other elements of the metabolic syndrome. Recent studies have shown that non-alcoholic fatty liver disease (NAFLD) is a critical pathway to metabolic syndrome. This model assesses the health and economic benefits of interventions aimed at reducing intake of added sugars. Methods Using data from US National Health Surveys and current literature, we simulated an open cohort, for the period 2015–2035. We constructed a microsimulation model with Markov chains for NAFLD (including steatosis, non-alcoholic steatohepatitis (NASH), cirrhosis and hepatocellular carcinoma (HCC)), body mass index, T2D and CHD. We assessed reductions in population disease prevalence, disease-attributable disability-adjusted life years (DALYs) and costs, with interventions that reduce added sugars consumption by either 20% or 50%. Findings The model estimated that a 20% reduction in added sugars intake will reduce prevalence of hepatic steatosis, NASH, cirrhosis, HCC, obesity, T2D and CHD. Incidence of T2D and CHD would be expected to decrease by 19.9 (95% CI 12.8 to 27.0) and 9.4 (95% CI 3.1 to 15.8) cases per 100 000 people after 20 years, respectively. A 20% reduction in consumption is also projected to annually avert 0.767 million (M) DALYs (95% CI 0.757M to 0.777M) and a total of US$10.3 billion (B) (95% CI 10.2B to 10.4B) in discounted direct medical costs by 2035. These effects increased proportionally when added sugars intake were reduced by 50%. Conclusions The decrease in incidence and prevalence of disease is similar to results in other models, but averted costs and DALYs were higher, mainly due to inclusion of NAFLD and CHD. The model suggests that efforts to reduce consumption of added sugars may result in significant public health and economic benefits. PMID:28775179

  5. DC parameter extraction of equivalent circuit model in InGaAsSb heterojunction bipolar transistors including non-ideal effects in the base region

    Science.gov (United States)

    Chang, Yang-Hua; Cheng, Zong-Tai

    2011-07-01

    This paper presents the DC parameter extraction of the equivalent circuit model in an InP-InGaAsSb double heterojunction bipolar transistor (HBT). The non-ideal collector current is modeled by a non-ideal doping distribution in the base region. Then several consequent non-ideal effects, which have always been neglected in typical HBTs, are studied using Medici device simulator. Moreover, the associated DC parameters of VBIC model are extracted accordingly. The equivalent circuit model is in good agreement with the measured data in I C- V CE characteristics.

  6. Progressive IRP Models for Power Resources Including EPP

    Directory of Open Access Journals (Sweden)

    Yiping Zhu

    2017-01-01

    Full Text Available In the view of optimizing regional power supply and demand, the paper makes effective planning scheduling of supply and demand side resources including energy efficiency power plant (EPP, to achieve the target of benefit, cost, and environmental constraints. In order to highlight the characteristics of different supply and demand resources in economic, environmental, and carbon constraints, three planning models with progressive constraints are constructed. Results of three models by the same example show that the best solutions to different models are different. The planning model including EPP has obvious advantages considering pollutant and carbon emission constraints, which confirms the advantages of low cost and emissions of EPP. The construction of progressive IRP models for power resources considering EPP has a certain reference value for guiding the planning and layout of EPP within other power resources and achieving cost and environmental objectives.

  7. Jet-calculus approach including coherence effects

    International Nuclear Information System (INIS)

    Jones, L.M.; Migneron, R.; Narayanan, K.S.S.

    1987-01-01

    We show how integrodifferential equations typical of jet calculus can be combined with an averaging procedure to obtain jet-calculus-based results including the Mueller interference graphs. Results in longitudinal-momentum fraction x for physical quantities are higher at intermediate x and lower at large x than with the conventional ''incoherent'' jet calculus. These results resemble those of Marchesini and Webber, who used a Monte Carlo approach based on the same dynamics

  8. Structural Optimization Including Centrifugal and Coriolis Effects

    Science.gov (United States)

    1988-01-01

    the desired frequency changes with excellent accuracy. MSC/ NASTRAN finite element solution sequences were modified to incorporate rotary effects. DMAP ...properties can be altered by a nonlinear change factor. These manipulations may be done by selective use of the MATMOD DMAP module. In the MSC/ NASTRAN ...Examples were carried out using the general purpose software package MSC/ NASTRAN and ADS (Automated Design Synthesis). "I OTIC copy INSpE TE 6

  9. Olkiluoto surface hydrological modelling: Update 2012 including salt transport modelling

    International Nuclear Information System (INIS)

    Karvonen, T.

    2013-11-01

    Posiva Oy is responsible for implementing a final disposal program for spent nuclear fuel of its owners Teollisuuden Voima Oyj and Fortum Power and Heat Oy. The spent nuclear fuel is planned to be disposed at a depth of about 400-450 meters in the crystalline bedrock at the Olkiluoto site. Leakages located at or close to spent fuel repository may give rise to the upconing of deep highly saline groundwater and this is a concern with regard to the performance of the tunnel backfill material after the closure of the tunnels. Therefore a salt transport sub-model was added to the Olkiluoto surface hydrological model (SHYD). The other improvements include update of the particle tracking algorithm and possibility to estimate the influence of open drillholes in a case where overpressure in inflatable packers decreases causing a hydraulic short-circuit between hydrogeological zones HZ19 and HZ20 along the drillhole. Four new hydrogeological zones HZ056, HZ146, BFZ100 and HZ039 were added to the model. In addition, zones HZ20A and HZ20B intersect with each other in the new structure model, which influences salinity upconing caused by leakages in shafts. The aim of the modelling of long-term influence of ONKALO, shafts and repository tunnels provide computational results that can be used to suggest limits for allowed leakages. The model input data included all the existing leakages into ONKALO (35-38 l/min) and shafts in the present day conditions. The influence of shafts was computed using eight different values for total shaft leakage: 5, 11, 20, 30, 40, 50, 60 and 70 l/min. The selection of the leakage criteria for shafts was influenced by the fact that upconing of saline water increases TDS-values close to the repository areas although HZ20B does not intersect any deposition tunnels. The total limit for all leakages was suggested to be 120 l/min. The limit for HZ20 zones was proposed to be 40 l/min: about 5 l/min the present day leakages to access tunnel, 25 l/min from

  10. Mathematical model for predicting topographical properties of poly (ε-caprolactone) melt electrospun scaffolds including the effects of temperature and linear transitional speed

    International Nuclear Information System (INIS)

    Ko, Junghyuk; Mohtaram, Nima Khadem; Willerth, Stephanie M; Jun, Martin B G; Lee, Patrick C

    2015-01-01

    Melt electrospinning can be used to fabricate various fibrous biomaterial scaffolds with a range of mechanical properties and varying topographical properties for different applications such as tissue scaffold and filtration and etc, making it a powerful technique. Engineering the topography of such electrospun microfibers can be easily done by tuning the operational parameters of this process. Recent experimental studies have shown promising results for fabricating various topographies, but there is no body of work that focuses on using mathematical models of this technique to further understand the effect of operational parameters on these properties of microfiber scaffolds. In this study, we developed a novel mathematical model using numerical simulations to demonstrate the effect of temperature, feed rate and flow rate on controlling topographical properties such as fiber diameter of these spun fibrous scaffolds. These promising modelling results are also compared to our previous and current experimental results. Overall, we show that our novel mathematical model can predict the topographical properties affected by key operational parameters such as change in temperature, flow rate and feed rate, and this model could serve as a promising strategy for the controlling of topographical properties of such structures for different applications. (paper)

  11. Effects of Obstacles on the Dynamics of Kinesins, Including Velocity and Run Length, Predicted by a Model of Two Dimensional Motion.

    Directory of Open Access Journals (Sweden)

    Woochul Nam

    Full Text Available Kinesins are molecular motors which walk along microtubules by moving their heads to different binding sites. The motion of kinesin is realized by a conformational change in the structure of the kinesin molecule and by a diffusion of one of its two heads. In this study, a novel model is developed to account for the 2D diffusion of kinesin heads to several neighboring binding sites (near the surface of microtubules. To determine the direction of the next step of a kinesin molecule, this model considers the extension in the neck linkers of kinesin and the dynamic behavior of the coiled-coil structure of the kinesin neck. Also, the mechanical interference between kinesins and obstacles anchored on the microtubules is characterized. The model predicts that both the kinesin velocity and run length (i.e., the walking distance before detaching from the microtubule are reduced by static obstacles. The run length is decreased more significantly by static obstacles than the velocity. Moreover, our model is able to predict the motion of kinesin when other (several motors also move along the same microtubule. Furthermore, it suggests that the effect of mechanical interaction/interference between motors is much weaker than the effect of static obstacles. Our newly developed model can be used to address unanswered questions regarding degraded transport caused by the presence of excessive tau proteins on microtubules.

  12. Up-scaling of a two-phase flow model including gravity effect in geological heterogeneous media: application to CO2 sequestration

    International Nuclear Information System (INIS)

    Ngo, Tri-Dat

    2016-01-01

    This work deals with the mathematical modeling and the numerical simulation of the migration under gravity and capillarity effects of the supercritical CO 2 injected into a geological heterogeneous sequestration site. The simulations are performed with the code DuMux. Particularly, we consider the up-scaling, from the cell scale to the reservoir scale, of a two-phase (CO 2 -brine) flow model within a periodic stratified medium made up of horizontal low permeability barriers, continuous or discontinuous. The up-scaling is done by the two-scale asymptotic method. First, we consider perfectly layered media. An homogenized model is developed and validated by numerical simulation for different values of capillary number and the incident flux of CO 2 . The homogenization method is then applied to the case of a two-dimensional medium made up of discontinuous layers. Due to the gravity effect, the CO 2 accumulates under the low permeability layers, which leads to a non-standard local mathematical problem. This stratification is modeled using the gravity current approach. This approach is then extended to the case of semi-permeable strata taking into account the capillarity. The up-scaled model is compared with numerical simulations for different types of layers, with or without capillary pressure, and its limit of validity is discussed in each of these cases. The final part of this thesis is devoted to the study of the parallel computing performances of the code DuMux to simulate the injection and migration of CO 2 in three-dimensional heterogeneous media (layered periodic media, fluvial media and reservoir model SPE 10). (author) [fr

  13. Estimation of torque on mechanical heart valves due to magnetic resonance imaging including an estimation of the significance of the Lenz effect using a computational model

    Energy Technology Data Exchange (ETDEWEB)

    Robertson, Neil M. [44 Ardgowan Street, Greenock PA16 8EL (United Kingdom). E-mail: neil.robertson at physics.org; Diaz-Gomez, Manuel [Plaza Alcalde Horacio Hermoso, 2, 3-A 41013 Seville (Spain). E-mail: manolo-diaz at latinmail.com; Condon, Barrie [Department of Clinical Physics, Institute of Neurological Sciences, Glasgow G51 4TF (United Kingdom). E-mail: barrie.condon at udcf.gla.ac.uk

    2000-12-01

    Mitral and aortic valve replacement is a procedure which is common in cardiac surgery. Some of these replacement valves are mechanical and contain moving metal parts. Should the patient in whom such a valve has been implanted be involved in magnetic resonance imaging, there is a possible dangerous interaction between the moving metal parts and the static magnetic field due to the Lenz effect. Mathematical models of two relatively common forms of single-leaflet valves have been derived and the magnitude of the torque which opposes the motion of the valve leaflet has been calculated for a valve disc of solid metal. In addition, a differential model of a ring-strengthener valve type has been considered to determine the likely significance of the Lenz effect in the context of the human heart. For common magnetic field strengths at present, i.e. 1 to 2 T, the effect is not particularly significant. However, there is a marked increase in back pressure as static magnetic field strength increases. There are concerns that, since field strengths in the range 3 to 4 T are increasingly being used, the Lenz effect could become significant. At 5 to 10 T the malfunction of the mechanical heart valve could cause the heart to behave as though it is diseased. For unhealthy or old patients this could possibly prove fatal. (author)

  14. Microfluidic System Simulation Including the Electro-Viscous Effect

    Science.gov (United States)

    Rojas, Eileen; Chen, C. P.; Majumdar, Alok

    2007-01-01

    This paper describes a practical approach using a general purpose lumped-parameter computer program, GFSSP (Generalized Fluid System Simulation Program) for calculating flow distribution in a network of micro-channels including electro-viscous effects due to the existence of electrical double layer (EDL). In this study, an empirical formulation for calculating an effective viscosity of ionic solutions based on dimensional analysis is described to account for surface charge and bulk fluid conductivity, which give rise to electro-viscous effect in microfluidics network. Two dimensional slit micro flow data was used to determine the model coefficients. Geometry effect is then included through a Poiseuille number correlation in GFSSP. The bi-power model was used to calculate flow distribution of isotropically etched straight channel and T-junction microflows involving ionic solutions. Performance of the proposed model is assessed against experimental test data.

  15. Modeling the fields of magneto-optical devices, including fringe field effects and higher order multipole contributions, with application to charged particle optics

    Directory of Open Access Journals (Sweden)

    R. M. G. M. Trines

    2001-06-01

    Full Text Available A new method for the calculation of the magnetic field of beam guiding elements is presented. The method relates the calculation to measurement data of the magnetic field in a direct way. It can be applied to single beam guiding elements as well as to clusters of elements. The presented description of the magnetic field differs from the classical approach in that it does not rely on power series approximations. It is also both divergence free and curl free, and takes fringe field effects up to any desired order into account. In the field description, pseudodifferential operators described by Bessel functions are used to obtain the various multipole contributions. Magnetic field data on a two-dimensional surface, e.g., a cylindrical surface or median plane, serve as input for the calculation of the three-dimensional magnetic field. A boundary element method is presented to fit the fields to a discrete set of field data, obtained, for instance, from field measurements, on the two-dimensional surface. Relative errors in the field approximation do not exceed the maximal relative errors in the input data. Methods for incorporating the obtained field in both analytical and numerical computation of transfer functions are outlined. Applications include easy calculation of the transfer functions of clusters of beam guiding elements and of generalized field gradients for any multipole contribution up to any order.

  16. Stochastic modelling of two-phase flows including phase change

    International Nuclear Information System (INIS)

    Hurisse, O.; Minier, J.P.

    2011-01-01

    Stochastic modelling has already been developed and applied for single-phase flows and incompressible two-phase flows. In this article, we propose an extension of this modelling approach to two-phase flows including phase change (e.g. for steam-water flows). Two aspects are emphasised: a stochastic model accounting for phase transition and a modelling constraint which arises from volume conservation. To illustrate the whole approach, some remarks are eventually proposed for two-fluid models. (authors)

  17. Application of a model of plastic porous materials including void shape effects to the prediction of ductile failure under shear-dominated loadings

    DEFF Research Database (Denmark)

    Morin, Léo; Leblond, Jean Baptiste; Tvergaard, Viggo

    2016-01-01

    , a numerical implementation of the model is proposed and incorporated into the SYSTUS® and ABAQUS® finite element programmes (through some freely available UMAT (Leblond, 2015) in the second case). Second, the implementation in SYSTUS® is used to simulate previous "numerical experiments" of Tvergaard...

  18. New modeling of reflection interference contrast microscopy including polarization and numerical aperture effects: application to nanometric distance measurements and object profile reconstruction.

    Science.gov (United States)

    Theodoly, O; Huang, Z-H; Valignat, M-P

    2010-02-02

    We have developed a new and improved optical model of reflection interference contrast microscopy (RICM) to determine with a precision of a few nanometers the absolute thickness h of thin films on a flat surface in immersed conditions. The model takes into account multiple reflections between a planar surface and a multistratified object, finite aperture illumination (INA), and, for the first time, the polarization of light. RICM intensity I is typically oscillating with h. We introduce a new normalization procedure that uses the intensity extrema of the same oscillation order for both experimental and theoretical intensity values and permits us to avoid significant error in the absolute height determination, especially at high INA. We also show how the problem of solution degeneracy can be solved by taking pictures at two different INA values. The model is applied to filled polystyrene beads and giant unilamellar vesicles of radius 10-40 microm sitting on a glass substrate. The RICM profiles I(h) can be fitted for up to two to three oscillation orders, and extrema positions are correct for up to five to seven oscillation orders. The precision of the absolute distance and of the shape of objects near a substrate is about 5 nm in a range from 0 to 500 nm, even under large numerical aperture conditions. The method is especially valuable for dynamic RICM experiments and with living cells where large illumination apertures are required.

  19. Including investment risk in large-scale power market models

    DEFF Research Database (Denmark)

    Lemming, Jørgen Kjærgaard; Meibom, P.

    2003-01-01

    can be included in large-scale partial equilibrium models of the power market. The analyses are divided into a part about risk measures appropriate for power market investors and a more technical part about the combination of a risk-adjustment model and a partial-equilibrium model. To illustrate...... the analyses quantitatively, a framework based on an iterative interaction between the equilibrium model and a separate risk-adjustment module was constructed. To illustrate the features of the proposed modelling approach we examined how uncertainty in demand and variable costs affects the optimal choice...

  20. Generalized fluid theory including non-Maxwellian kinetic effects

    Science.gov (United States)

    Izacard, Olivier

    2017-04-01

    The results obtained by the plasma physics community for the validation and the prediction of turbulence and transport in magnetized plasmas come mainly from the use of very central processing unit (CPU)-consuming particle-in-cell or (gyro)kinetic codes which naturally include non-Maxwellian kinetic effects. To date, fluid codes are not considered to be relevant for the description of these kinetic effects. Here, after revisiting the limitations of the current fluid theory developed in the 19th century, we generalize the fluid theory including kinetic effects such as non-Maxwellian super-thermal tails with as few fluid equations as possible. The collisionless and collisional fluid closures from the nonlinear Landau Fokker-Planck collision operator are shown for an arbitrary collisionality. Indeed, the first fluid models associated with two examples of collisionless fluid closures are obtained by assuming an analytic non-Maxwellian distribution function (e.g. the INMDF (Izacard, O. 2016b Kinetic corrections from analytic non-Maxwellian distribution functions in magnetized plasmas. Phys. Plasmas 23, 082504) that stands for interpreted non-Maxwellian distribution function). One of the main differences with the literature is our analytic representation of the distribution function in the velocity phase space with as few hidden variables as possible thanks to the use of non-orthogonal basis sets. These new non-Maxwellian fluid equations could initiate the next generation of fluid codes including kinetic effects and can be expanded to other scientific disciplines such as astrophysics, condensed matter or hydrodynamics. As a validation test, we perform a numerical simulation based on a minimal reduced INMDF fluid model. The result of this test is the discovery of the origin of particle and heat diffusion. The diffusion is due to the competition between a growing INMDF on short time scales due to spatial gradients and the thermalization on longer time scales. The results

  1. Including spatial data in nutrient balance modelling on dairy farms

    Science.gov (United States)

    van Leeuwen, Maricke; van Middelaar, Corina; Stoof, Cathelijne; Oenema, Jouke; Stoorvogel, Jetse; de Boer, Imke

    2017-04-01

    The Annual Nutrient Cycle Assessment (ANCA) calculates the nitrogen (N) and phosphorus (P) balance at a dairy farm, while taking into account the subsequent nutrient cycles of the herd, manure, soil and crop components. Since January 2016, Dutch dairy farmers are required to use ANCA in order to increase understanding of nutrient flows and to minimize nutrient losses to the environment. A nutrient balance calculates the difference between nutrient inputs and outputs. Nutrients enter the farm via purchased feed, fertilizers, deposition and fixation by legumes (nitrogen), and leave the farm via milk, livestock, manure, and roughages. A positive balance indicates to which extent N and/or P are lost to the environment via gaseous emissions (N), leaching, run-off and accumulation in soil. A negative balance indicates that N and/or P are depleted from soil. ANCA was designed to calculate average nutrient flows on farm level (for the herd, manure, soil and crop components). ANCA was not designed to perform calculations of nutrient flows at the field level, as it uses averaged nutrient inputs and outputs across all fields, and it does not include field specific soil characteristics. Land management decisions, however, such as the level of N and P application, are typically taken at the field level given the specific crop and soil characteristics. Therefore the information that ANCA provides is likely not sufficient to support farmers' decisions on land management to minimize nutrient losses to the environment. This is particularly a problem when land management and soils vary between fields. For an accurate estimate of nutrient flows in a given farming system that can be used to optimize land management, the spatial scale of nutrient inputs and outputs (and thus the effect of land management and soil variation) could be essential. Our aim was to determine the effect of the spatial scale of nutrient inputs and outputs on modelled nutrient flows and nutrient use efficiencies

  2. Two-dimensional analysis of motion artifacts, including flow effects

    International Nuclear Information System (INIS)

    Litt, A.M.; Brody, A.S.; Spangler, R.A.; Scott, P.D.

    1990-01-01

    The effects of motion on magnetic resonance images have been theoretically analyzed for the case of a point-like object in simple harmonic motion and for other one-dimensional trajectories. The authors of this paper extend this analysis to a generalized two-dimensional magnetization with an arbitrary motion trajectory. The authors provide specific solutions for the clinically relevant cases of the cross-sections of cylindrical objects in the body, such as the aorta, which has a roughly one-dimensional, simple harmonic motion during respiration. By extending the solution to include inhomogeneous magnetizations, the authors present a model which allows the effects of motion artifacts and flow artifacts to be analyzed simultaneously

  3. Neutrinos from Cosmic Accelerators including Magnetic Field and Flavor Effects

    Directory of Open Access Journals (Sweden)

    Walter Winter

    2012-01-01

    Full Text Available We review the particle physics ingredients affecting the normalization, shape, and flavor composition of astrophysical neutrinos fluxes, such as different production modes, magnetic field effects on the secondaries (muons, pions, and kaons, and flavor mixing, where we focus on pγ interactions. We also discuss the interplay with neutrino propagation and detection, including the possibility to detect flavor and its application in particle physics, and the use of the Glashow resonance to discriminate pγ from pp interactions in the source. We illustrate the implications on fluxes and flavor composition with two different models: (1 the target photon spectrum is dominated by synchrotron emission of coaccelerated electrons and (2 the target photon spectrum follows the observed photon spectrum of gamma-ray bursts. In the latter case, the multimessenger extrapolation from the gamma-ray fluence to the expected neutrino flux is highlighted.

  4. Parton recombination model including resonance production. RL-78-040

    International Nuclear Information System (INIS)

    Roberts, R.G.; Hwa, R.C.; Matsuda, S.

    1978-05-01

    Possible effects of resonance production on the meson inclusive distribution in the fragmentation region are investigated in the framework of the parton recombination model. From a detailed study of the data on vector-meson production, a reliable ratio of the vector-to-pseudoscalar rates is determined. Then the influence of the decay of the vector mesons on the pseudoscalar spectrum is examined, and the effect found to be no more than 25% for x > 0.5. The normalization of the non-strange antiquark distributions are still higher than those in a quiescent proton. The agreement between the calculated results and data remain very good. 36 references

  5. Including lateral interactions into microkinetic models of catalytic reactions

    DEFF Research Database (Denmark)

    Hellman, Anders; Honkala, Johanna Karoliina

    2007-01-01

    In many catalytic reactions lateral interactions between adsorbates are believed to have a strong influence on the reaction rates. We apply a microkinetic model to explore the effect of lateral interactions and how to efficiently take them into account in a simple catalytic reaction. Three differ...... different approximations are investigated: site, mean-field, and quasichemical approximations. The obtained results are compared to accurate Monte Carlo numbers. In the end, we apply the approximations to a real catalytic reaction, namely, ammonia synthesis....

  6. Exclusive queueing model including the choice of service windows

    Science.gov (United States)

    Tanaka, Masahiro; Yanagisawa, Daichi; Nishinari, Katsuhiro

    2018-01-01

    In a queueing system involving multiple service windows, choice behavior is a significant concern. This paper incorporates the choice of service windows into a queueing model with a floor represented by discrete cells. We contrived a logit-based choice algorithm for agents considering the numbers of agents and the distances to all service windows. Simulations were conducted with various parameters of agent choice preference for these two elements and for different floor configurations, including the floor length and the number of service windows. We investigated the model from the viewpoint of transit times and entrance block rates. The influences of the parameters on these factors were surveyed in detail and we determined that there are optimum floor lengths that minimize the transit times. In addition, we observed that the transit times were determined almost entirely by the entrance block rates. The results of the presented model are relevant to understanding queueing systems including the choice of service windows and can be employed to optimize facility design and floor management.

  7. Extending PSA models including ageing and asset management - 15291

    International Nuclear Information System (INIS)

    Martorell, S.; Marton, I.; Carlos, S.; Sanchez, A.I.

    2015-01-01

    This paper proposes a new approach to Ageing Probabilistic Safety Assessment (APSA) modelling, which is intended to be used to support risk-informed decisions on the effectiveness of maintenance management programs and technical specification requirements of critical equipment of Nuclear Power Plants (NPP) within the framework of the Risk Informed Decision Making according to R.G. 1.174 principles. This approach focuses on the incorporation of not only equipment ageing but also effectiveness of maintenance and efficiency of surveillance testing explicitly into APSA models and data. This methodology is applied to a motor-operated valve of the auxiliary feed water system (AFWS) of a PWR. This simple example of application focuses on a critical safety-related equipment of a NPP in order to evaluate the risk impact of considering different approaches to APSA and the combined effect of equipment ageing and maintenance and testing alternatives along NPP design life. The risk impact of several alternatives in maintenance strategy is discussed

  8. A geometrically exact Cosserat shell-model including size effects, avoiding degeneracy in the thin shell limit. Part I: Formal dimensional reduction for elastic plates and existence of minimizers for positive Cosserat couple modulus

    Science.gov (United States)

    Neff, P.

    2004-10-01

    This contribution is concerned with a consistent formal dimensional reduction of a previously introduced finite-strain three-dimensional Cosserat micropolar elasticity model to the two-dimensional situation of thin plates and shells. Contrary to the direct modelling of a shell as a Cosserat surface with additional directors, we obtain the shell model from the Cosserat bulk model which already includes a triad of rigid directors. The reduction is achieved by assumed kinematics, quadratic through the thickness. The three-dimensional transverse boundary conditions can be evaluated analytically in terms of the assumed kinematics and determines exactly two appearing coefficients in the chosen ansatz. Further simplifications with subsequent analytical integration through the thickness determine the reduced model in a variational setting. The resulting membrane energy turns out to be a quadratic, elliptic, first order, non degenerate energy in contrast to classical approaches. The bending contribution is augmented by a curvature term representing an additional stiffness of the Cosserat model and the corresponding system of balance equations remains of second order. The lateral boundary conditions for simple support are non-standard. The model includes size-effects, transverse shear resistance, drilling degrees of freedom and accounts implicitly for thickness extension and asymmetric shift of the midsurface. The formal thin shell “membrane” limit without classical h 3-bending term is non-degenerate due to the additional Cosserat curvature stiffness and control of drill rotations. In our formulation, the drill-rotations are strictly related to the size-effects of the bulk model and not introduced artificially for numerical convenience. Upon linearization with zero Cosserat couple modulus μ_c = 0 we recover the well known infinitesimal-displacement Reissner-Mindlin model without size-effects and without drill-rotations. It is shown that the dimensionally reduced

  9. Magnetic properties of nickel halide hydrates including deuteration effects

    Energy Technology Data Exchange (ETDEWEB)

    DeFotis, G.C., E-mail: gxdefo@wm.edu [Chemistry Department, College of William & Mary, Williamsburg, VA, 23187 United States (United States); Van Dongen, M.J.; Hampton, A.S.; Komatsu, C.H.; Trowell, K.T.; Havas, K.C.; Davis, C.M.; DeSanto, C.L. [Chemistry Department, College of William & Mary, Williamsburg, VA, 23187 United States (United States); Hays, K.; Wagner, M.J. [Chemistry Department, George Washington University, Washington, DC, 20052 United States (United States)

    2017-01-01

    Magnetic measurements on variously hydrated nickel chlorides and bromides, including deuterated forms, are reported. Results include locations and sizes of susceptibility maxima, T{sub max} and χ{sub max}, ordering temperatures T{sub c}, Curie constants and Weiss theta in the paramagnetic regime, and primary and secondary exchange interactions from analysis of low temperature data. For the latter a 2D Heisenberg model augmented by interlayer exchange in a mean-field approximation is applied. Magnetization data to 16 kG as a function of temperature show curvature and hysteresis characteristics quite system dependent. For four materials high field magnetization data to 70 kG at 2.00 K are also obtained. Comparison is made with theoretical relations for spin-1 models. Trends are apparent, primarily that T{sub max} of each bromide hydrate is less than for the corresponding chloride, and that for a given halide nD{sub 2}O (n=1 or 2) deuterates exhibit lesser T{sub max} than do nH{sub 2}O hydrates. A monoclinic unit cell determined from powder X-ray diffraction data on NiBr{sub 2}·2D{sub 2}O is different from and slightly larger than that of NiBr{sub 2}·2H{sub 2}O. This provides some rationale for the difference in magnetic properties between these. - Highlights: • The magnetism of Ni(II) chloride and bromide dihydrates and monohydrates is studied. • Effects of replacing H{sub 2}O by D{sub 2}O are examined for both hydration states and both halides. • Exchange interactions in bromides are weaker than in corresponding chlorides. • Exchange interactions are weaker in D{sub 2}O than in corresponding H{sub 2}O containing systems. • The unit cell of NiBr{sub 2}·2D{sub 2}O is different from and slightly larger than that of NiBr{sub 2}·2H{sub 2}O.

  10. Homogenization of long fiber reinforced composites including fiber bending effects

    DEFF Research Database (Denmark)

    Poulios, Konstantinos; Niordson, Christian Frithiof

    2016-01-01

    of the reinforcing fibers is captured by higher order strain terms, resulting in an accurate representation of the micro-mechanical behavior of the composite. Numerical examples show that the accuracy of the proposed model is very close to a non-homogenized finite-element model with an explicit discretization......This paper presents a homogenization method, which accounts for intrinsic size effects related to the fiber diameter in long fiber reinforced composite materials with two independent constitutive models for the matrix and fiber materials. A new choice of internal kinematic variables allows...... to maintain the kinematics of the two material phases independent from the assumed constitutive models, so that stress-deformation relationships, can be expressed in the framework of hyper-elasticity and hyper-elastoplasticity for the fiber and the matrix materials respectively. The bending stiffness...

  11. Single-Phase Bundle Flows Including Macroscopic Turbulence Model

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Seung Jun; Yoon, Han Young [KAERI, Daejeon (Korea, Republic of); Yoon, Seok Jong; Cho, Hyoung Kyu [Seoul National University, Seoul (Korea, Republic of)

    2016-05-15

    To deal with various thermal hydraulic phenomena due to rapid change of fluid properties when an accident happens, securing mechanistic approaches as much as possible may reduce the uncertainty arising from improper applications of the experimental models. In this study, the turbulence mixing model, which is well defined in the subchannel analysis code such as VIPRE, COBRA, and MATRA by experiments, is replaced by a macroscopic k-e turbulence model, which represents the aspect of mathematical derivation. The performance of CUPID with macroscopic turbulence model is validated against several bundle experiments: CNEN 4x4 and PNL 7x7 rod bundle tests. In this study, the macroscopic k-e model has been validated for the application to subchannel analysis. It has been implemented in the CUPID code and validated against CNEN 4x4 and PNL 7x7 rod bundle tests. The results showed that the macroscopic k-e turbulence model can estimate the experiments properly.

  12. LTRACK: Beam-transport calculation including wakefield effects

    International Nuclear Information System (INIS)

    Chan, K.C.D.; Cooper, R.K.

    1988-01-01

    LTRACK is a first-order beam-transport code that includes wakefield effects up to quadrupole modes. This paper will introduce the readers to this computer code by describing the history, the method of calculations, and a brief summary of the input/output information. Future plans for the code will also be described

  13. Infliximab, adalimumab and golimumab for treating moderately to severely active ulcerative colitis after the failure of conventional therapy (including a review of TA140 and TA262): clinical effectiveness systematic review and economic model.

    Science.gov (United States)

    Archer, Rachel; Tappenden, Paul; Ren, Shijie; Martyn-St James, Marrissa; Harvey, Rebecca; Basarir, Hasan; Stevens, John; Carroll, Christopher; Cantrell, Anna; Lobo, Alan; Hoque, Sami

    2016-05-01

    Ulcerative colitis (UC) is the most common form of inflammatory bowel disease in the UK. UC can have a considerable impact on patients' quality of life. The burden for the NHS is substantial. To evaluate the clinical effectiveness and safety of interventions, to evaluate the incremental cost-effectiveness of all interventions and comparators (including medical and surgical options), to estimate the expected net budget impact of each intervention, and to identify key research priorities. Peer-reviewed publications, European Public Assessment Reports and manufacturers' submissions. The following databases were searched from inception to December 2013 for clinical effectiveness searches and from inception to January 2014 for cost-effectiveness searches for published and unpublished research evidence: MEDLINE, EMBASE, Cumulative Index to Nursing and Allied Health Literature, The Cochrane Library including the Cochrane Systematic Reviews Database, Cochrane Controlled Trials Register, Database of Abstracts of Reviews of Effects, the Health Technology Assessment database and NHS Economic Evaluation Database; ISI Web of Science, including Science Citation Index, and the Conference Proceedings Citation Index-Science and Bioscience Information Service Previews. The US Food and Drug Administration website and the European Medicines Agency website were also searched, as were research registers, conference proceedings and key journals. A systematic review [including network meta-analysis (NMA)] was conducted to evaluate the clinical effectiveness and safety of named interventions. The health economic analysis included a review of published economic evaluations and the development of a de novo model. Ten randomised controlled trials were included in the systematic review. The trials suggest that adult patients receiving infliximab (IFX) [Remicade(®), Merck Sharp & Dohme Ltd (MSD)], adalimumab (ADA) (Humira(®), AbbVie) or golimumab (GOL) (Simponi(®), MSD) were more likely to

  14. Global atmospheric model for mercury including oxidation by bromine atoms

    Directory of Open Access Journals (Sweden)

    C. D. Holmes

    2010-12-01

    Full Text Available Global models of atmospheric mercury generally assume that gas-phase OH and ozone are the main oxidants converting Hg0 to HgII and thus driving mercury deposition to ecosystems. However, thermodynamic considerations argue against the importance of these reactions. We demonstrate here the viability of atomic bromine (Br as an alternative Hg0 oxidant. We conduct a global 3-D simulation with the GEOS-Chem model assuming gas-phase Br to be the sole Hg0 oxidant (Hg + Br model and compare to the previous version of the model with OH and ozone as the sole oxidants (Hg + OH/O3 model. We specify global 3-D Br concentration fields based on our best understanding of tropospheric and stratospheric Br chemistry. In both the Hg + Br and Hg + OH/O3 models, we add an aqueous photochemical reduction of HgII in cloud to impose a tropospheric lifetime for mercury of 6.5 months against deposition, as needed to reconcile observed total gaseous mercury (TGM concentrations with current estimates of anthropogenic emissions. This added reduction would not be necessary in the Hg + Br model if we adjusted the Br oxidation kinetics downward within their range of uncertainty. We find that the Hg + Br and Hg + OH/O3 models are equally capable of reproducing the spatial distribution of TGM and its seasonal cycle at northern mid-latitudes. The Hg + Br model shows a steeper decline of TGM concentrations from the tropics to southern mid-latitudes. Only the Hg + Br model can reproduce the springtime depletion and summer rebound of TGM observed at polar sites; the snowpack component of GEOS-Chem suggests that 40% of HgII deposited to snow in the Arctic is transferred to the ocean and land reservoirs, amounting to a net deposition flux to the Arctic of 60 Mg a−1. Summertime events of depleted Hg0 at Antarctic sites due to subsidence are much better simulated by

  15. Two improvements to the dynamic wake meandering model: including the effects of atmospheric shear on wake turbulence and incorporating turbulence build-up in a row of wind turbines

    DEFF Research Database (Denmark)

    Keck, Rolf-Erik; de Mare, Martin Tobias; Churchfield, Matthew J.

    2015-01-01

    The dynamic wake meandering (DWM) model is an engineering wake model designed to physically model the wake deficit evolution and the unsteady meandering that occurs in wind turbine wakes. The present study aims at improving two features of the model: The effect of the atmospheric boundary layer s...

  16. Plasmon modes of metallic nanowires including quantum nonlocal effects

    Energy Technology Data Exchange (ETDEWEB)

    Moradi, Afshin, E-mail: a.moradi@kut.ac.ir [Department of Engineering Physics, Kermanshah University of Technology, Kermanshah, Iran and Department of Nano Sciences, Institute for Studies in Theoretical Physics and Mathematics (IPM), Tehran (Iran, Islamic Republic of)

    2015-03-15

    The properties of electrostatic surface and bulk plasmon modes of cylindrical metallic nanowires are investigated, using the quantum hydrodynamic theory of plasmon excitation which allows an analytical study of quantum tunneling effects through the Bohm potential term. New dispersion relations are obtained for each type of mode and their differences with previous treatments based on the standard hydrodynamic model are analyzed in detail. Numerical results show by considering the quantum effects, as the value of wave number increases, the surface modes are slightly red-shifted first and then blue-shifted while the bulk modes are blue-shifted.

  17. Thematic report: Macroeconomic models including specifically social and environmental aspects

    OpenAIRE

    Kratena, Kurt

    2015-01-01

    WWWforEurope Deliverable No. 8, 30 pages A significant reduction of the global environmental consequences of European consumption and production activities are the main objective of the policy simulations carried out in this paper. For this purpose three different modelling approaches have been chosen. Two macroeconomic models following the philosophy of consistent stock-flow accounting for the main institutional sectors (households, firms, banks, central bank and government) are used for...

  18. Identifying Clusters with Mixture Models that Include Radial Velocity Observations

    Science.gov (United States)

    Czarnatowicz, Alexis; Ybarra, Jason E.

    2018-01-01

    The study of stellar clusters plays an integral role in the study of star formation. We present a cluster mixture model that considers radial velocity data in addition to spatial data. Maximum likelihood estimation through the Expectation-Maximization (EM) algorithm is used for parameter estimation. Our mixture model analysis can be used to distinguish adjacent or overlapping clusters, and estimate properties for each cluster.Work supported by awards from the Virginia Foundation for Independent Colleges (VFIC) Undergraduate Science Research Fellowship and The Research Experience @Bridgewater (TREB).

  19. Unsteady panel method for complex configurations including wake modeling

    CSIR Research Space (South Africa)

    Van Zyl, Lourens H

    2008-01-01

    Full Text Available The calculation of unsteady air loads is an essential step in any aeroelastic analysis. The subsonic doublet lattice method (DLM) is used extensively for this purpose due to its simplicity and reliability. The body models available with the popular...

  20. Double-photoionization of helium including quadrupole radiation effects

    Energy Technology Data Exchange (ETDEWEB)

    Colgan, James [Los Alamos National Laboratory; Ludlow, J A [AUBURN UNIV; Lee, Teck - Ghee [AUBURN UNIV; Pindzola, M S [AUBURN UNIV; Robicheaux, F [AUBURN UNIV

    2009-01-01

    Non-perturbative time-dependent close-coupling calculations are carried out for the double photoionization of helium including both dipole and quadrupole radiation effects. At a photon energy of 800 eV, accessible at CUlTent synchrotron light sources, the quadrupole interaction contributes around 6% to the total integral double photoionization cross section. The pure quadrupole single energy differential cross section shows a local maxima at equal energy sharing, as opposed to the minimum found in the pure dipole single energy differential cross section. The sum of the pure dipole and pure quadrupole single energy differentials is insensitive to non-dipole effects at 800 eV. However, the triple differential cross section at equal energy sharing of the two ejected electrons shows strong non-dipole effects due to the quadrupole interaction that may be experimentally observable.

  1. A stochastic model of gene expression including splicing events

    OpenAIRE

    Penim, Flávia Alexandra Mendes

    2014-01-01

    Tese de mestrado, Bioinformática e Biologia Computacional, Universidade de Lisboa, Faculdade de Ciências, 2014 Proteins carry out the great majority of the catalytic and structural work within an organism. The RNA templates used in their synthesis determines their identity, and this is dictated by which genes are transcribed. Therefore, gene expression is the fundamental determinant of an organism’s nature. The main objective of this thesis was to develop a stochastic computational model a...

  2. Aeroelastic modal dynamics of wind turbines including anisotropic effects

    DEFF Research Database (Denmark)

    Skjoldan, Peter Fisker

    and the computationally efficient implicit Floquet analysis in anisotropic conditions. The tool is validated against system identifications with the partial Floquet method on the nonlinear BHawC model of a 2.3 MW wind turbine. System identification results show that nonlinear effects on the 2.3 MW turbine in most cases....... These harmonics appear in calculated frequency responses of the turbine. Extreme wind shear changes the modal damping when the flow is separated due to an interaction between the periodic mode shape and the local aerodynamic damping influenced by a periodic variation in angle of attack....

  3. Double folding model including the Pauli exclusion principle

    International Nuclear Information System (INIS)

    Gridnev, K.A.; Soubbotin, V.B.; Oertzen, W. von; Bohlen, H.G.; Vinas, X.

    2002-01-01

    A new method to incorporate the Pauli principle into the double folding approach to the heavy ion potential is proposed. It is shown that in order to take into account the Pauli blocking a redefinition of the density matrices of the free isolated nuclei must be one. A solution to the self-consistent incorporation of the Pauli-blocking effects in the mean-field nucleus-nucleus potential is obtained in the Thomas-Fermi approximation [ru

  4. Double-folding model including the Pauli exclusion principle

    International Nuclear Information System (INIS)

    Gridnev, K.A.; Soubbotin, V.B.; Oertzen, W. von; Bohlen, H.G.; Vinas, X.

    2002-01-01

    A new method for incorporating the Pauli exclusion principle into the double-folding approach to the heavy-ion potential is proposed. The description of the exchange terms at the level of the semiclassical one-body density matrix is used. It is shown that, in order to take into account Pauli blocking properly, the density matrices of free isolated nuclei must be redefined. A solution to the self-consistent incorporation of Pauli blocking effects in the mean-field nucleus-nucleus potential is obtained in the Thomas-Fermi approximation

  5. Enhanced UWB Radio Channel Model for Short-Range Communication Scenarios Including User Dynamics

    DEFF Research Database (Denmark)

    Kovacs, Istvan Zsolt; Nguyen, Tuan Hung; Eggers, Patrick Claus F.

    2005-01-01

    channel model represents an enhancement of the existing IEEE 802.15.3a/4a PAN channel model, where antenna and user-proximity effects are not included. Our investigations showed that significant variations of the received wideband power and time-delay signal clustering are possible due the human body...

  6. Shunted Piezoelectric Vibration Damping Analysis Including Centrifugal Loading Effects

    Science.gov (United States)

    Min, James B.; Duffy, Kirsten P.; Provenza, Andrew J.

    2011-01-01

    Excessive vibration of turbomachinery blades causes high cycle fatigue problems which require damping treatments to mitigate vibration levels. One method is the use of piezoelectric materials as passive or active dampers. Based on the technical challenges and requirements learned from previous turbomachinery rotor blades research, an effort has been made to investigate the effectiveness of a shunted piezoelectric for the turbomachinery rotor blades vibration control, specifically for a condition with centrifugal rotation. While ample research has been performed on the use of a piezoelectric material with electric circuits to attempt to control the structural vibration damping, very little study has been done regarding rotational effects. The present study attempts to fill this void. Specifically, the objectives of this study are: (a) to create and analyze finite element models for harmonic forced response vibration analysis coupled with shunted piezoelectric circuits for engine blade operational conditions, (b) to validate the experimental test approaches with numerical results and vice versa, and (c) to establish a numerical modeling capability for vibration control using shunted piezoelectric circuits under rotation. Study has focused on a resonant damping control using shunted piezoelectric patches on plate specimens. Tests and analyses were performed for both non-spinning and spinning conditions. The finite element (FE) shunted piezoelectric circuit damping simulations were performed using the ANSYS Multiphysics code for the resistive and inductive circuit piezoelectric simulations of both conditions. The FE results showed a good correlation with experimental test results. Tests and analyses of shunted piezoelectric damping control, demonstrating with plate specimens, show a great potential to reduce blade vibrations under centrifugal loading.

  7. Aeroelastic modal dynamics of wind turbines including anisotropic effects

    Energy Technology Data Exchange (ETDEWEB)

    Fisker Skjoldan, P.

    2011-03-15

    Several methods for aeroelastic modal analysis of a rotating wind turbine are developed and used to analyse the modal dynamics of two simplified models and a complex model in isotropic and anisotropic conditions. The Coleman transformation is used to enable extraction of the modal frequencies, damping, and periodic mode shapes of a rotating wind turbine by describing the rotor degrees of freedom in the inertial frame. This approach is valid only for an isotropic system. Anisotropic systems, e.g., with an unbalanced rotor or operating in wind shear, are treated with the general approaches of Floquet analysis or Hill's method which do not provide a unique reference frame for observing the modal frequency, to which any multiple of the rotor speed can be added. This indeterminacy is resolved by requiring that the periodic mode shape be as constant as possible in the inertial frame. The modal frequency is thus identified as the dominant frequency in the response of a pure excitation of the mode observed in the inertial frame. A modal analysis tool based directly on the complex aeroelastic wind turbine code BHawC is presented. It uses the Coleman approach in isotropic conditions and the computationally efficient implicit Floquet analysis in anisotropic conditions. The tool is validated against system identifications with the partial Floquet method on the nonlinear BHawC model of a 2.3 MW wind turbine. System identification results show that nonlinear effects on the 2.3 MW turbine in most cases are small, but indicate that the controller creates nonlinear damping. In isotropic conditions the periodic mode shape contains up to three harmonic components, but in anisotropic conditions it can contain an infinite number of harmonic components with frequencies that are multiples of the rotor speed. These harmonics appear in calculated frequency responses of the turbine. Extreme wind shear changes the modal damping when the flow is separated due to an interaction between

  8. Potential energy surface for ? dissociation including spin-orbit effects

    Science.gov (United States)

    Siebert, Matthew R.; Aquino, Adelia J. A.; de Jong, Wibe A.; Granucci, Giovanni; Hase, William L.

    2012-10-01

    Previous experiments [J. Phys. Chem. A 116, 2833 (2012)] have studied the dissociation of 1,2-diiodoethane radical cation ( ? ) and found a one-dimensional distribution of translational energy, an odd finding considering most product relative translational energy distributions are two-dimensional. The goal of this study is to obtain an accurate understanding of the potential energy surface (PES) topology for the unimolecular decomposition reaction ? → C2H4I+ + I•. This is done through comparison of many single-reference electronic structure methods, coupled-cluster single-point (energy) calculations, and multi-reference energy calculations used to quantify spin-orbit (SO) coupling effects. We find that the structure of the ? reactant has a substantial effect on the role of the SO coupling on the reaction energy. Both the BHandH and MP2 theories with an ECP/6-31++G** basis set, and without SO coupling corrections, provide accurate models for the reaction energetics. MP2 theory gives an unsymmetric structure with different C-I bond lengths, resulting in a SO energy for ? similar to that for the product I-atom and a negligible SO correction to the reaction energy. In contrast, DFT gives a symmetric structure for ? , similar to that of the neutral C2H4I2 parent, resulting in a substantial SO correction and increasing the reaction energy by 6.0-6.5 kcalmol-1. Also, we find that, for this system, coupled-cluster single-point energy calculations are inaccurate, since a small change in geometry can lead to a large change in energy.

  9. Evaluation of fatigue data including reactor water environmental effects

    International Nuclear Information System (INIS)

    Rosinski, S.T.; Nickell, R.E.; Van Der Sluys, W.A.; Yukawa, S.

    2002-01-01

    Laboratory data have been gathered in the past decade indicating a significant reduction in component fatigue life when reactor water environmental effects are experimentally simulated. However, these laboratory data have not been supported by nuclear power plant component operating experience. The laboratory data under simulated operating conditions are being used to support arguments for revising the design-basis fatigue curves in the ASME Code Section III, Division 1, for Class 1 components. A thorough review of available laboratory fatigue data and their applicability to actual component operating conditions was performed. The evaluation divided the assembly, review and assessment of existing laboratory fatigue data and its applicability to plant operating conditions into four principal tasks: (1) review of available laboratory data relative to thresholds for environmental parameters, such as temperature, reactor water oxidation potential, strain rate, strain amplitude, reactor water flow rate, and component metal sulfur content; (2) determination of the relevance of the laboratory data to actual plant operating conditions; (3) review of laboratory S-N data curve-fitting models; and (4) assessment of existing ASME Code Section III Class 1 margins This paper summarizes the results of the data review. In addition, recommendations are made for additional laboratory testing intended to improve the applicability of laboratory test results under simulated reactor water environmental conditions. (authors)

  10. Mathematical modeling of the hypothalamic–pituitary–adrenal gland (HPA) axis, including hippocampal mechanisms

    DEFF Research Database (Denmark)

    Andersen, Morten; Vinther, Frank; Ottesen, Johnny T.

    2013-01-01

    This paper presents a mathematical model of the HPA axis. The HPA axis consists of the hypothalamus, the pituitary and the adrenal glands in which the three hormones CRH, ACTH and cortisol interact through receptor dynamics. Furthermore, it has been suggested that receptors in the hippocampus have...... an influence on the axis.A model is presented with three coupled, non-linear differential equations, with the hormones CRH, ACTH and cortisol as variables. The model includes the known features of the HPA axis, and includes the effects from the hippocampus through its impact on CRH in the hypothalamus...

  11. Impact on total population health and societal cost, and the implication on the actual cost-effectiveness of including tumour necrosis factor-α antagonists in management of ankylosing spondylitis: a dynamic population modelling study.

    Science.gov (United States)

    Tran-Duy, An; Boonen, Annelies; van de Laar, Mart A F J; Severens, Johan L

    2015-01-01

    Sequential treatment of ankylosing spondylitis (AS) that includes tumour necrosis factor-α antagonists (anti-TNF agents) has been applied in most of the Western countries. Existing cost-effectiveness (CE) models almost exclusively presented the incremental CE of anti-TNF agents using a closed cohort while budget impact studies are mainly lacking. Notwithstanding, information on impact on total population health and societal budget as well as on actual incremental CE for a given decision time span are important for decision makers. This study aimed at quantifying, for different decision time spans starting from January 1, 2014 in the Dutch society, (1) impact of sequential drug treatment strategies without and with inclusion of anti-TNF agents (Strategies 1 and 2, respectively) on total population health and societal cost, and (2) the actual incremental CE of Strategy 2 compared to Strategy 1. Dynamic population modelling was used to capture total population health and cost, and the actual incremental CE. Distinguishing the prevalent AS population on January 1, 2014 and the incident AS cohorts in the subsequent 20 years, the model tracked individually an actual number of AS patients until death or end of the simulation time. During the simulation, data on patient characteristics, history of drug use, costs and health at discrete time points were generated. In Strategy 1, five nonsteroidal anti-inflammatory drugs (NSAIDs) were available but anti-TNF agents withdrawn. In Strategy 2, five NSAIDs and two anti-TNF agents continued to be available. The predicted size of the prevalent AS population in the Dutch society varied within the range of 67,145-69,957 with 44-46 % of the patients receiving anti-TNF agents over the period 2014-2034. The use of anti-TNF agents resulted in an increase in the annual drug costs (168.54-205.28 million Euros), but at the same time caused a decrease in the annual productivity costs (12.58-31.21 million Euros) and in annual costs of

  12. Microscopic description of production cross sections including deexcitation effects

    Science.gov (United States)

    Sekizawa, Kazuyuki

    2017-07-01

    Background: At the forefront of the nuclear science, production of new neutron-rich isotopes is continuously pursued at accelerator laboratories all over the world. To explore the currently unknown territories in the nuclear chart far away from the stability, reliable theoretical predictions are inevitable. Purpose: To provide a reliable prediction of production cross sections taking into account secondary deexcitation processes, both particle evaporation and fission, a new method called TDHF+GEMINI is proposed, which combines the microscopic time-dependent Hartree-Fock (TDHF) theory with a sophisticated statistical compound-nucleus deexcitation model, GEMINI++. Methods: Low-energy heavy ion reactions are described based on three-dimensional Skyrme-TDHF calculations. Using the particle-number projection method, production probabilities, total angular momenta, and excitation energies of primary reaction products are extracted from the TDHF wave function after collision. Production cross sections for secondary reaction products are evaluated employing GEMINI++. Results are compared with available experimental data and widely used grazing calculations. Results: The method is applied to describe cross sections for multinucleon transfer processes in 40Ca+124Sn (Ec .m .≃128.54 MeV ), 48Ca+124Sn (Ec .m .≃125.44 MeV ), 40Ca+208Pb (Ec .m .≃208.84 MeV ), 58Ni+208Pb (Ec .m .≃256.79 MeV ), 64Ni+238U (Ec .m .≃307.35 MeV ), and 136Xe+198Pt (Ec .m .≃644.98 MeV ) reactions at energies close to the Coulomb barrier. It is shown that the inclusion of secondary deexcitation processes, which are dominated by neutron evaporation in the present systems, substantially improves agreement with the experimental data. The magnitude of the evaporation effects is very similar to the one observed in grazing calculations. TDHF+GEMINI provides better description of the absolute value of the cross sections for channels involving transfer of more than one proton, compared to the grazing

  13. Infliximab, adalimumab and golimumab for treating moderately to severely active ulcerative colitis after the failure of conventional therapy (including a review of TA140 and TA262): clinical effectiveness systematic review and economic model.

    OpenAIRE

    Archer, R.; Tappenden, P.; Ren, S.; Martyn-St James, M.; Harvey, R.; Basarir, H.; Stevens, J.; Carroll, C.; Cantrell, A.; Lobo, A.; Hoque, S.

    2016-01-01

    BACKGROUND: Ulcerative colitis (UC) is the most common form of inflammatory bowel disease in the UK. UC can have a considerable impact on patients' quality of life. The burden for the NHS is substantial. OBJECTIVES: To evaluate the clinical effectiveness and safety of interventions, to evaluate the incremental cost-effectiveness of all interventions and comparators (including medical and surgical options), to estimate the expected net budget impact of each intervention, and to identify key re...

  14. Transient motion of hypersonic vehicles including time history effects

    Science.gov (United States)

    Hui, W. H.; Van Roessel, H. J.

    1985-01-01

    An analytic method is developed for calculating the transient pitching motion of a wedge in hypersonic flow, taking into account fully the interaction between its motion and the unsteady air flow passing it. The effects of past motion history on the present state of motion are shown to be caused by the wave reflection from the bow shock. In the Newtonian limit they are equivalent to that of an added moment of inertia. The time history effects generally tend to decrease the damping, rendering the oscillatory motion more persistent. Numerical examples are given.

  15. Aerodynamic heating of ballistic missile including the effects of gravity

    Indian Academy of Sciences (India)

    The aerodynamic heating of a ballistic missile due to only convection is analysed taking into consideration the effects of gravity. The amount of heat transferred to the wetted area and to the nose region has been separately determined, unlike A Miele's treatise without consideration of gravity. The peak heating ratesto the ...

  16. Aerodynamic heating of ballistic missile including the effects of gravity

    Indian Academy of Sciences (India)

    Abstract. The aerodynamic heating of a ballistic missile due to only convection is analysed taking into consideration the effects of gravity. The amount of heat transferred to the wetted area and to the nose region has been separately determined, unlike A Miele's treatise without consideration of gravity. The peak heating rates ...

  17. Aerodynamic heating of ballistic missile including the effects of gravity

    Indian Academy of Sciences (India)

    http://www.ias.ac.in/article/fulltext/sadh/025/05/0463-0473. Keywords. Aerodynamic heating; ballistic missile; gravity; flat-earth. Abstract. The aerodynamic heating of a ballistic missile due to only convection is analysed taking into consideration the effects of gravity. The amount of heat transferred to the wetted area and to the ...

  18. Dipole model analysis of highest precision HERA data, including very low Q2's

    International Nuclear Information System (INIS)

    Luszczak, A.; Kowalski, H.

    2016-12-01

    We analyse, within a dipole model, the final, inclusive HERA DIS cross section data in the low χ region, using fully correlated errors. We show, that these highest precision data are very well described within the dipole model framework starting from Q 2 values of 3.5 GeV 2 to the highest values of Q 2 =250 GeV 2 . To analyze the saturation effects we evaluated the data including also the very low 0.35including this region show a preference of the saturation ansatz.

  19. BALANCED SCORECARDS EVALUATION MODEL THAT INCLUDES ELEMENTS OF ENVIRONMENTAL MANAGEMENT SYSTEM USING AHP MODEL

    Directory of Open Access Journals (Sweden)

    Jelena Jovanović

    2010-03-01

    Full Text Available The research is oriented on improvement of environmental management system (EMS using BSC (Balanced Scorecard model that presents strategic model of measurem ents and improvement of organisational performance. The research will present approach of objectives and environmental management me trics involvement (proposed by literature review in conventional BSC in "Ad Barska plovi dba" organisation. Further we will test creation of ECO-BSC model based on business activities of non-profit organisations in order to improve envir onmental management system in parallel with other systems of management. Using this approach we may obtain 4 models of BSC that includ es elements of environmen tal management system for AD "Barska plovidba". Taking into acc ount that implementation and evaluation need long period of time in AD "Barska plovidba", the final choice will be based on 14598 (Information technology - Software product evaluation and ISO 9126 (Software engineering - Product quality using AHP method. Those standards are usually used for evaluation of quality software product and computer programs that serve in organisation as support and factors for development. So, AHP model will be bas ed on evolution criteria based on suggestion of ISO 9126 standards and types of evaluation from two evaluation teams. Members of team & will be experts in BSC and environmental management system that are not em ployed in AD "Barska Plovidba" organisation. The members of team 2 will be managers of AD "Barska Plovidba" organisation (including manage rs from environmental department. Merging results based on previously cr eated two AHP models, one can obtain the most appropriate BSC that includes elements of environmental management system. The chosen model will present at the same time suggestion for approach choice including ecological metrics in conventional BSC model for firm that has at least one ECO strategic orientation.

  20. Improvement of prediction ability for genomic selection of dairy cattle by including dominance effects.

    Directory of Open Access Journals (Sweden)

    Chuanyu Sun

    Full Text Available Dominance may be an important source of non-additive genetic variance for many traits of dairy cattle. However, nearly all prediction models for dairy cattle have included only additive effects because of the limited number of cows with both genotypes and phenotypes. The role of dominance in the Holstein and Jersey breeds was investigated for eight traits: milk, fat, and protein yields; productive life; daughter pregnancy rate; somatic cell score; fat percent and protein percent. Additive and dominance variance components were estimated and then used to estimate additive and dominance effects of single nucleotide polymorphisms (SNPs. The predictive abilities of three models with both additive and dominance effects and a model with additive effects only were assessed using ten-fold cross-validation. One procedure estimated dominance values, and another estimated dominance deviations; calculation of the dominance relationship matrix was different for the two methods. The third approach enlarged the dataset by including cows with genotype probabilities derived using genotyped ancestors. For yield traits, dominance variance accounted for 5 and 7% of total variance for Holsteins and Jerseys, respectively; using dominance deviations resulted in smaller dominance and larger additive variance estimates. For non-yield traits, dominance variances were very small for both breeds. For yield traits, including additive and dominance effects fit the data better than including only additive effects; average correlations between estimated genetic effects and phenotypes showed that prediction accuracy increased when both effects rather than just additive effects were included. No corresponding gains in prediction ability were found for non-yield traits. Including cows with derived genotype probabilities from genotyped ancestors did not improve prediction accuracy. The largest additive effects were located on chromosome 14 near DGAT1 for yield traits for both

  1. Performance Tests of Snow-Related Variables Over the Tibetan Plateau and Himalayas Using a New Version of NASA GEOS-5 Land Surface Model that Includes the Snow Darkening Effect

    Science.gov (United States)

    Yasunari, Tppei J.; Lau, K.-U.; Koster, Randal D.; Suarez, Max; Mahanama, Sarith; Dasilva, Arlindo M.; Colarco, Peter R.

    2011-01-01

    The snow darkening effect, i.e. the reduction of snow albedo, is caused by absorption of solar radiation by absorbing aerosols (dust, black carbon, and organic carbon) deposited on the snow surface. This process is probably important over Himalayan and Tibetan glaciers due to the transport of highly polluted Atmospheric Brown Cloud (ABC) from the Indo-Gangetic Plain (IGP). This effect has been incorporated into the NASA Goddard Earth Observing System model, version 5 (GEOS-5) atmospheric transport model. The Catchment land surface model (LSM) used in GEOS-5 considers 3 snow layers. Code was developed to track the mass concentration of aerosols in the three layers, taking into account such processes as the flushing of the compounds as liquid water percolates through the snowpack. In GEOS-5, aerosol emissions, transports, and depositions are well simulated in the Goddard Chemistry Aerosol Radiation and Transport (GO CART) module; we recently made the connection between GOCART and the GEOS-5 system fitted with the revised LSM. Preliminary simulations were performed with this new system in "replay" mode (i.e., with atmospheric dynamics guided by reanalysis) at 2x2.5 degree horizontal resolution, covering the period 1 November 2005 - 31 December 2009; we consider the final three years of simulation here. The three simulations used the following variants of the LSM: (1) the original Catchment LSM with a fixed fresh snowfall density of 150 kg m-3 ; (2) the LSM fitted with the new snow albedo code, used here without aerosol deposition but with changes in density formulation and melting water effect on snow specific surface area, (3) the LSM fitted with the new snow albedo code as same as (2) but with fixed aerosol deposition rates (computed from GOCART values averaged over the Tibetan Plateau domain [Ion.: 60-120E; lat.: 20-50N] during March-May 2008) applied to all grid points at every time step. For (2) and (3), the same setting on the fresh snowfall density as in (1

  2. A New Circuit Model for Spin-Torque Oscillator Including Perpendicular Torque of Magnetic Tunnel Junction

    Directory of Open Access Journals (Sweden)

    Hyein Lim

    2013-01-01

    Full Text Available Spin-torque oscillator (STO is a promising new technology for the future RF oscillators, which is based on the spin-transfer torque (STT effect in magnetic multilayered nanostructure. It is expected to provide a larger tunability, smaller size, lower power consumption, and higher level of integration than the semiconductor-based oscillators. In our previous work, a circuit-level model of the giant magnetoresistance (GMR STO was proposed. In this paper, we present a physics-based circuit-level model of the magnetic tunnel junction (MTJ-based STO. MTJ-STO model includes the effect of perpendicular torque that has been ignored in the GMR-STO model. The variations of three major characteristics, generation frequency, mean oscillation power, and generation linewidth of an MTJ-STO with respect to the amount of perpendicular torque, are investigated, and the results are applied to our model. The operation of the model was verified by HSPICE simulation, and the results show an excellent agreement with the experimental data. The results also prove that a full circuit-level simulation with MJT-STO devices can be made with our proposed model.

  3. Improving weather predictability by including land-surface model parameter uncertainty

    Science.gov (United States)

    Orth, Rene; Dutra, Emanuel; Pappenberger, Florian

    2016-04-01

    The land surface forms an important component of Earth system models and interacts nonlinearly with other parts such as ocean and atmosphere. To capture the complex and heterogenous hydrology of the land surface, land surface models include a large number of parameters impacting the coupling to other components of the Earth system model. Focusing on ECMWF's land-surface model HTESSEL we present in this study a comprehensive parameter sensitivity evaluation using multiple observational datasets in Europe. We select 6 poorly constrained effective parameters (surface runoff effective depth, skin conductivity, minimum stomatal resistance, maximum interception, soil moisture stress function shape, total soil depth) and explore their sensitivity to model outputs such as soil moisture, evapotranspiration and runoff using uncoupled simulations and coupled seasonal forecasts. Additionally we investigate the possibility to construct ensembles from the multiple land surface parameters. In the uncoupled runs we find that minimum stomatal resistance and total soil depth have the most influence on model performance. Forecast skill scores are moreover sensitive to the same parameters as HTESSEL performance in the uncoupled analysis. We demonstrate the robustness of our findings by comparing multiple best performing parameter sets and multiple randomly chosen parameter sets. We find better temperature and precipitation forecast skill with the best-performing parameter perturbations demonstrating representativeness of model performance across uncoupled (and hence less computationally demanding) and coupled settings. Finally, we construct ensemble forecasts from ensemble members derived with different best-performing parameterizations of HTESSEL. This incorporation of parameter uncertainty in the ensemble generation yields an increase in forecast skill, even beyond the skill of the default system. Orth, R., E. Dutra, and F. Pappenberger, 2016: Improving weather predictability by

  4. A High-Rate, Single-Crystal Model including Phase Transformations, Plastic Slip, and Twinning

    Energy Technology Data Exchange (ETDEWEB)

    Addessio, Francis L. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States). Theoretical Division; Bronkhorst, Curt Allan [Los Alamos National Lab. (LANL), Los Alamos, NM (United States). Theoretical Division; Bolme, Cynthia Anne [Los Alamos National Lab. (LANL), Los Alamos, NM (United States). Explosive Science and Shock Physics Division; Brown, Donald William [Los Alamos National Lab. (LANL), Los Alamos, NM (United States). Materials Science and Technology Division; Cerreta, Ellen Kathleen [Los Alamos National Lab. (LANL), Los Alamos, NM (United States). Materials Science and Technology Division; Lebensohn, Ricardo A. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States). Materials Science and Technology Division; Lookman, Turab [Los Alamos National Lab. (LANL), Los Alamos, NM (United States). Theoretical Division; Luscher, Darby Jon [Los Alamos National Lab. (LANL), Los Alamos, NM (United States). Theoretical Division; Mayeur, Jason Rhea [Los Alamos National Lab. (LANL), Los Alamos, NM (United States). Theoretical Division; Morrow, Benjamin M. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States). Materials Science and Technology Division; Rigg, Paulo A. [Washington State Univ., Pullman, WA (United States). Dept. of Physics. Inst. for Shock Physics

    2016-08-09

    An anisotropic, rate-­dependent, single-­crystal approach for modeling materials under the conditions of high strain rates and pressures is provided. The model includes the effects of large deformations, nonlinear elasticity, phase transformations, and plastic slip and twinning. It is envisioned that the model may be used to examine these coupled effects on the local deformation of materials that are subjected to ballistic impact or explosive loading. The model is formulated using a multiplicative decomposition of the deformation gradient. A plate impact experiment on a multi-­crystal sample of titanium was conducted. The particle velocities at the back surface of three crystal orientations relative to the direction of impact were measured. Molecular dynamics simulations were conducted to investigate the details of the high-­rate deformation and pursue issues related to the phase transformation for titanium. Simulations using the single crystal model were conducted and compared to the high-­rate experimental data for the impact loaded single crystals. The model was found to capture the features of the experiments.

  5. Performance tests of snow-related variables over the Tibetan Plateau and Himalayas using a new version of NASA GEOS-5 land surface model that includes the snow darkening effect

    Science.gov (United States)

    Yasunari, T. J.; Lau, W. K.; Koster, R. D.; Suarez, M.; Mahanama, S. P.; da Silva, A.; Colarco, P. R.

    2011-12-01

    The snow darkening effect, i.e. the reduction of snow albedo, is caused by absorption of solar radiation by absorbing aerosols (dust, black carbon, and organic carbon) deposited on the snow surface. This process is probably important over Himalayan and Tibetan glaciers due to the transport of highly polluted Atmospheric Brown Cloud (ABC) from the Indo-Gangetic Plain (IGP). This effect has been incorporated into the NASA Goddard Earth Observing System model, version 5 (GEOS-5) atmospheric transport model. The Catchment land surface model (LSM) used in GEOS-5 considers 3 snow layers. Code was developed to track the mass concentration of aerosols in the three layers, taking into account such processes as the flushing of the compounds as liquid water percolates through the snowpack. In GEOS-5, aerosol emissions, transports, and depositions are well simulated in the Goddard Chemistry Aerosol Radiation and Transport (GOCART) module; we recently made the connection between GOCART and the GEOS-5 system fitted with the revised LSM. Preliminary simulations were performed with this new system in "replay" mode (i.e., with atmospheric dynamics guided by reanalysis) at 2x2.5 degree horizontal resolution, covering the period 1 November 2005 - 31 December 2009; we consider the final three years of simulation here. The three simulations used the following variants of the LSM: (1) the original Catchment LSM with a fixed fresh snowfall density of 150 kg m-3; (2) the LSM fitted with the new snow albedo code, used here without aerosol deposition but with changes in density formulation and melting water effect on snow specific surface area, (3) the LSM fitted with the new snow albedo code as same as (2) but with fixed aerosol deposition rates (computed from GOCART values averaged over the Tibetan Plateau domain [lon.: 60-120E; lat.: 20-50N] during March-May 2008) applied to all grid points at every time step. For (2) and (3), the same setting on the fresh snowfall density as in (1) was

  6. A numerical model including PID control of a multizone crystal growth furnace

    Science.gov (United States)

    Panzarella, Charles H.; Kassemi, Mohammad

    1992-01-01

    This paper presents a 2D axisymmetric combined conduction and radiation model of a multizone crystal growth furnace. The model is based on a programmable multizone furnace (PMZF) designed and built at NASA Lewis Research Center for growing high quality semiconductor crystals. A novel feature of this model is a control algorithm which automatically adjusts the power in any number of independently controlled heaters to establish the desired crystal temperatures in the furnace model. The control algorithm eliminates the need for numerous trial and error runs previously required to obtain the same results. The finite element code, FIDAP, used to develop the furnace model, was modified to directly incorporate the control algorithm. This algorithm, which presently uses PID control, and the associated heat transfer model are briefly discussed. Together, they have been used to predict the heater power distributions for a variety of furnace configurations and desired temperature profiles. Examples are included to demonstrate the effectiveness of the PID controlled model in establishing isothermal, Bridgman, and other complicated temperature profies in the sample. Finally, an example is given to show how the algorithm can be used to change the desired profile with time according to a prescribed temperature-time evolution.

  7. A 3D model of the oculomotor plant including the pulley system

    Science.gov (United States)

    Viegener, A.; Armentano, R. L.

    2007-11-01

    Early models of the oculomotor plant only considered the eye globes and the muscles that move them. Recently, connective tissue structures have been found enveloping the extraocular muscles (EOMs) and firmly anchored to the orbital wall. These structures act as pulleys; they determine the functional origin of the EOMs and, in consequence, their effective pulling direction. A three dimensional model of the oculomotor plant, including pulleys, has been developed and simulations in Simulink were performed during saccadic eye movements. Listing's law was implemented based on the supposition that there exists an eye orientation related signal. The inclusion of the pulleys in the model makes this assumption plausible and simplifies the problem of the plant noncommutativity.

  8. Mechanics of damping for fiber composite laminates including hygro-thermal effects

    Science.gov (United States)

    Saravanos, D. A.; Chamis, Christos C.

    1989-01-01

    An integrated mechanics theory was developed for the modeling of composite damping from the micromechanics to the laminate level. Simplified, design oriented equations based on hysteretic damping are presented for on-axis plies, off-axis plies, and laminates including the effect of temperature, moisture, and interply hysteretic damping. The temperature rise within vibrating composite laminates resulting from strain energy dissipation is also modeled, and their coupled hygro-thermo-mechanical response is predicted. The method correlates well with reported damping measurements. Application examples illustrate the effect of various ply, laminate, and hygro-thermal parameters on the overall damping performance of composite laminates.

  9. Health Promotion Behavior of Chinese International Students in Korea Including Acculturation Factors: A Structural Equation Model.

    Science.gov (United States)

    Kim, Sun Jung; Yoo, Il Young

    2016-03-01

    The purpose of this study was to explain the health promotion behavior of Chinese international students in Korea using a structural equation model including acculturation factors. A survey using self-administered questionnaires was employed. Data were collected from 272 Chinese students who have resided in Korea for longer than 6 months. The data were analyzed using structural equation modeling. The p value of final model is .31. The fitness parameters of the final model such as goodness of fit index, adjusted goodness of fit index, normed fit index, non-normed fit index, and comparative fit index were more than .95. Root mean square of residual and root mean square error of approximation also met the criteria. Self-esteem, perceived health status, acculturative stress and acculturation level had direct effects on health promotion behavior of the participants and the model explained 30.0% of variance. The Chinese students in Korea with higher self-esteem, perceived health status, acculturation level, and lower acculturative stress reported higher health promotion behavior. The findings can be applied to develop health promotion strategies for this population. Copyright © 2016. Published by Elsevier B.V.

  10. The Lag Model, a Turbulence Model for Wall Bounded Flows Including Separation

    Science.gov (United States)

    Olsen, Michael E.; Coakley, Thomas J.; Kwak, Dochan (Technical Monitor)

    2001-01-01

    A new class of turbulence model is described for wall bounded, high Reynolds number flows. A specific turbulence model is demonstrated, with results for favorable and adverse pressure gradient flowfields. Separation predictions are as good or better than either Spalart Almaras or SST models, do not require specification of wall distance, and have similar or reduced computational effort compared with these models.

  11. BioModels: expanding horizons to include more modelling approaches and formats.

    Science.gov (United States)

    Glont, Mihai; Nguyen, Tung V N; Graesslin, Martin; Hälke, Robert; Ali, Raza; Schramm, Jochen; Wimalaratne, Sarala M; Kothamachu, Varun B; Rodriguez, Nicolas; Swat, Maciej J; Eils, Jurgen; Eils, Roland; Laibe, Camille; Malik-Sheriff, Rahuman S; Chelliah, Vijayalakshmi; Le Novère, Nicolas; Hermjakob, Henning

    2018-01-04

    BioModels serves as a central repository of mathematical models representing biological processes. It offers a platform to make mathematical models easily shareable across the systems modelling community, thereby supporting model reuse. To facilitate hosting a broader range of model formats derived from diverse modelling approaches and tools, a new infrastructure for BioModels has been developed that is available at http://www.ebi.ac.uk/biomodels. This new system allows submitting and sharing of a wide range of models with improved support for formats other than SBML. It also offers a version-control backed environment in which authors and curators can work collaboratively to curate models. This article summarises the features available in the current system and discusses the potential benefit they offer to the users over the previous system. In summary, the new portal broadens the scope of models accepted in BioModels and supports collaborative model curation which is crucial for model reproducibility and sharing. © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

  12. A generalized model for optimal transport of images including dissipation and density modulation

    KAUST Repository

    Maas, Jan

    2015-11-01

    © EDP Sciences, SMAI 2015. In this paper the optimal transport and the metamorphosis perspectives are combined. For a pair of given input images geodesic paths in the space of images are defined as minimizers of a resulting path energy. To this end, the underlying Riemannian metric measures the rate of transport cost and the rate of viscous dissipation. Furthermore, the model is capable to deal with strongly varying image contrast and explicitly allows for sources and sinks in the transport equations which are incorporated in the metric related to the metamorphosis approach by Trouvé and Younes. In the non-viscous case with source term existence of geodesic paths is proven in the space of measures. The proposed model is explored on the range from merely optimal transport to strongly dissipative dynamics. For this model a robust and effective variational time discretization of geodesic paths is proposed. This requires to minimize a discrete path energy consisting of a sum of consecutive image matching functionals. These functionals are defined on corresponding pairs of intensity functions and on associated pairwise matching deformations. Existence of time discrete geodesics is demonstrated. Furthermore, a finite element implementation is proposed and applied to instructive test cases and to real images. In the non-viscous case this is compared to the algorithm proposed by Benamou and Brenier including a discretization of the source term. Finally, the model is generalized to define discrete weighted barycentres with applications to textures and objects.

  13. A multiscale model for glioma spread including cell-tissue interactions and proliferation.

    Science.gov (United States)

    Engwer, Christian; Knappitsch, Markus; Surulescu, Christina

    2016-04-01

    Glioma is a broad class of brain and spinal cord tumors arising from glia cells, which are the main brain cells that can develop into neoplasms. They are highly invasive and lead to irregular tumor margins which are not precisely identifiable by medical imaging, thus rendering a precise enough resection very difficult. The understanding of glioma spread patterns is hence essential for both radiological therapy as well as surgical treatment. In this paper we propose a multiscale model for glioma growth including interactions of the cells with the underlying tissue network, along with proliferative effects. Our current accounting for two subpopulations of cells to accomodate proliferation according to the go-or-grow dichtomoty is an extension of the setting in [16]. As in that paper, we assume that cancer cells use neuronal fiber tracts as invasive pathways. Hence, the individual structure of brain tissue seems to be decisive for the tumor spread. Diffusion tensor imaging (DTI) is able to provide such information, thus opening the way for patient specific modeling of glioma invasion. Starting from a multiscale model involving subcellular (microscopic) and individual (mesoscale) cell dynamics, we perform a parabolic scaling to obtain an approximating reaction-diffusion-transport equation on the macroscale of the tumor cell population. Numerical simulations based on DTI data are carried out in order to assess the performance of our modeling approach.

  14. Modelling Mediterranean agro-ecosystems by including agricultural trees in the LPJmL model

    Science.gov (United States)

    Fader, M.; von Bloh, W.; Shi, S.; Bondeau, A.; Cramer, W.

    2015-11-01

    In the Mediterranean region, climate and land use change are expected to impact on natural and agricultural ecosystems by warming, reduced rainfall, direct degradation of ecosystems and biodiversity loss. Human population growth and socioeconomic changes, notably on the eastern and southern shores, will require increases in food production and put additional pressure on agro-ecosystems and water resources. Coping with these challenges requires informed decisions that, in turn, require assessments by means of a comprehensive agro-ecosystem and hydrological model. This study presents the inclusion of 10 Mediterranean agricultural plants, mainly perennial crops, in an agro-ecosystem model (Lund-Potsdam-Jena managed Land - LPJmL): nut trees, date palms, citrus trees, orchards, olive trees, grapes, cotton, potatoes, vegetables and fodder grasses. The model was successfully tested in three model outputs: agricultural yields, irrigation requirements and soil carbon density. With the development presented in this study, LPJmL is now able to simulate in good detail and mechanistically the functioning of Mediterranean agriculture with a comprehensive representation of ecophysiological processes for all vegetation types (natural and agricultural) and in a consistent framework that produces estimates of carbon, agricultural and hydrological variables for the entire Mediterranean basin. This development paves the way for further model extensions aiming at the representation of alternative agro-ecosystems (e.g. agroforestry), and opens the door for a large number of applications in the Mediterranean region, for example assessments of the consequences of land use transitions, the influence of management practices and climate change impacts.

  15. Mathematical Model of Thyristor Inverter Including a Series-parallel Resonant Circuit

    Directory of Open Access Journals (Sweden)

    Miroslaw Luft

    2008-01-01

    Full Text Available The article presents a mathematical model of thyristor inverter including a series-parallel resonant circuit with theaid of state variable method. Maple procedures are used to compute current and voltage waveforms in the inverter.

  16. Mathematical model of thyristor inverter including a series-parallel resonant circuit

    OpenAIRE

    Luft, M.; Szychta, E.

    2008-01-01

    The article presents a mathematical model of thyristor inverter including a series-parallel resonant circuit with the aid of state variable method. Maple procedures are used to compute current and voltage waveforms in the inverter.

  17. Mathematical Model of Thyristor Inverter Including a Series-parallel Resonant Circuit

    OpenAIRE

    Miroslaw Luft; Elzbieta Szychta

    2008-01-01

    The article presents a mathematical model of thyristor inverter including a series-parallel resonant circuit with theaid of state variable method. Maple procedures are used to compute current and voltage waveforms in the inverter.

  18. Handbook of Modeling for Circuit Analysis Including Radiation Effects

    Science.gov (United States)

    1979-05-01

    Gererally, a single value of r’ oetween. rCSAT ,nd r3 is chosen.C,;ORMAL 1, "- OPE - r- r CNORPIAL#, CSAT / IC VCE Figure Iii-22. Method of DPtrrmiring rc III...integrated circuit testers or from custom teAt apparatus such as described in appendix 3 of reference VI-7. 1) Offset Voltage- a) By Measurement Offset voltage

  19. Refrigerant Performance Evaluation Including Effects of Transport Properties and Optimized Heat Exchangers.

    Science.gov (United States)

    Brignoli, Riccardo; Brown, J Steven; Skye, H; Domanski, Piotr A

    2017-08-01

    Preliminary refrigerant screenings typically rely on using cycle simulation models involving thermodynamic properties alone. This approach has two shortcomings. First, it neglects transport properties, whose influence on system performance is particularly strong through their impact on the performance of the heat exchangers. Second, the refrigerant temperatures in the evaporator and condenser are specified as input, while real-life equipment operates at imposed heat sink and heat source temperatures; the temperatures in the evaporator and condensers are established based on overall heat transfer resistances of these heat exchangers and the balance of the system. The paper discusses a simulation methodology and model that addresses the above shortcomings. This model simulates the thermodynamic cycle operating at specified heat sink and heat source temperature profiles, and includes the ability to account for the effects of thermophysical properties and refrigerant mass flux on refrigerant heat transfer and pressure drop in the air-to-refrigerant evaporator and condenser. Additionally, the model can optimize the refrigerant mass flux in the heat exchangers to maximize the Coefficient of Performance. The new model is validated with experimental data and its predictions are contrasted to those of a model based on thermodynamic properties alone.

  20. Atmosphere-soil-vegetation model including CO2 exchange processes: SOLVEG2

    International Nuclear Information System (INIS)

    Nagai, Haruyasu

    2004-11-01

    A new atmosphere-soil-vegetation model named SOLVEG2 (SOLVEG version 2) was developed to study the heat, water, and CO 2 exchanges between the atmosphere and land-surface. The model consists of one-dimensional multilayer sub-models for the atmosphere, soil, and vegetation. It also includes sophisticated processes for solar and long-wave radiation transmission in vegetation canopy and CO 2 exchanges among the atmosphere, soil, and vegetation. Although the model usually simulates only vertical variation of variables in the surface-layer atmosphere, soil, and vegetation canopy by using meteorological data as top boundary conditions, it can be used by coupling with a three-dimensional atmosphere model. In this paper, details of SOLVEG2, which includes the function of coupling with atmosphere model MM5, are described. (author)

  1. Exergoeconomic performance optimization for a steady-flow endoreversible refrigeration model including six typical cycles

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Lingen; Kan, Xuxian; Sun, Fengrui; Wu, Feng [College of Naval Architecture and Power, Naval University of Engineering, Wuhan 430033 (China)

    2013-07-01

    The operation of a universal steady flow endoreversible refrigeration cycle model consisting of a constant thermal-capacity heating branch, two constant thermal-capacity cooling branches and two adiabatic branches is viewed as a production process with exergy as its output. The finite time exergoeconomic performance optimization of the refrigeration cycle is investigated by taking profit rate optimization criterion as the objective. The relations between the profit rate and the temperature ratio of working fluid, between the COP (coefficient of performance) and the temperature ratio of working fluid, as well as the optimal relation between profit rate and the COP of the cycle are derived. The focus of this paper is to search the compromised optimization between economics (profit rate) and the utilization factor (COP) for endoreversible refrigeration cycles, by searching the optimum COP at maximum profit, which is termed as the finite-time exergoeconomic performance bound. Moreover, performance analysis and optimization of the model are carried out in order to investigate the effect of cycle process on the performance of the cycles using numerical example. The results obtained herein include the performance characteristics of endoreversible Carnot, Diesel, Otto, Atkinson, Dual and Brayton refrigeration cycles.

  2. Combining prior knowledge with data driven modeling of a batch distillation column including start-up

    NARCIS (Netherlands)

    van Lith, PF; Betlem, BHL; Roffel, B

    2003-01-01

    This paper presents the development of a simple model which describes the product quality and production over time of an experimental batch distillation column, including start-up. The model structure is based on a simple physical framework, which is augmented with fuzzy logic. This provides a way

  3. Including operational data in QMRA model: development and impact of model inputs.

    Science.gov (United States)

    Jaidi, Kenza; Barbeau, Benoit; Carrière, Annie; Desjardins, Raymond; Prévost, Michèle

    2009-03-01

    A Monte Carlo model, based on the Quantitative Microbial Risk Analysis approach (QMRA), has been developed to assess the relative risks of infection associated with the presence of Cryptosporidium and Giardia in drinking water. The impact of various approaches for modelling the initial parameters of the model on the final risk assessments is evaluated. The Monte Carlo simulations that we performed showed that the occurrence of parasites in raw water was best described by a mixed distribution: log-Normal for concentrations > detection limit (DL), and a uniform distribution for concentrations risks significantly. The mean annual risks for conventional treatment are: 1.97E-03 (removal credit adjusted by log parasite = log spores), 1.58E-05 (log parasite = 1.7 x log spores) or 9.33E-03 (regulatory credits based on the turbidity measurement in filtered water). Using full scale validated SCADA data, the simplified calculation of CT performed at the plant was shown to largely underestimate the risk relative to a more detailed CT calculation, which takes into consideration the downtime and system failure events identified at the plant (1.46E-03 vs. 3.93E-02 for the mean risk).

  4. Thermal histories of chondrules in solar nebula shocks, including the effect of molecular line cooling

    Science.gov (United States)

    Morris, Melissa A.

    Chondrules are millimeter-sized, silicate (mostly ferromagnesian) igneous spheres found within chondritic meteorites. They are some of the oldest materials in our Solar System, having formed within a few million years of its birth. Chondrules were melted at high temperature (over 1800 K), while they were free-floating objects in the early solar nebula. Their petrology and chemistry constrain their formation, especially their thermal histories. Chondrules provide some of the most powerful constraints on conditions in the solar nebula. Models in which chondrule precursors melted by passage through solar nebula shocks are very promising, and meet most constraints on chondrule formation in broad brush. However, these models have been lacking in some of the relevant physics. Previous shock models have used incorrect approximations to the input radiation boundary condition, and the opacity of solids has been treated simply. Most important, a proper treatment of cooling due to molecular line emission has not been included. In this thesis, the shock model is significantly improved in order to determine if it remains consistent with observational constraints. The appropriate boundary condition for the input radiation and the proper method for calculation of the opacity of solids are determined, and a complete treatment of molecular line cooling due to water is included. Previous estimates of the effect of line cooling predicted chondrule cooling rates in excess of 10,000 K per hour. However, once molecular line cooling due to water was incorporated into the full shock model, it was found that line cooling has a minimal effect on the thermal histories of gas and chondrules. This behavior is attributed mostly to the thermal buffering of the gas due to hydrogen dissociation and recombination, which tends to keep the gas temperature at approximately 2000 K until the column densities of water become optically thick to line emission. Chondrule cooling rates in the range of 10

  5. Transient Response Dynamic Module Modifications to Include Static and Kinetic Friction Effects

    Science.gov (United States)

    Misel, J. E.; Nenno, S. B.; Takahashi, D.

    1984-01-01

    A methodology that supports forced transient response dynamic solutions when both static and kinetic friction effects are included in a structural system model is described. Modifications that support this type of nonlinear transient response solution are summarized for the transient response dynamics (TRD) NASTRAN module. An overview of specific modifications for the NASTRAN processing subroutines, INITL, TRD1C, and TRD1D, are described with further details regarding inspection of nonlinear input definitions to define the type of nonlinear solution required, along with additional initialization requirements and specific calculation subroutines to successfully solve the transient response problem. The extension of the basic NASTRAN nonlinear methodology is presented through several stages of development to the point where constraint equations and residual flexibility effects are introduced into the finite difference Newmark-Beta recurrsion formulas. Particular emphasis is placed on cost effective solutions for large finite element models such as the Space Shuttle with friction degrees of freedom between the orbiter and payloads mounted in the cargo bay. An alteration to the dynamic finite difference equations of motion is discussed, which allows one to include friction effects at reasonable cost for large structural systems such as the Space Shuttle. Data are presented to indicate the possible impact of transient friction loads to the payload designer for the Space Shuttle. Transient response solution data are also included, which compare solutions without friction forces and those with friction forces for payloads mounted in the Space Shuttle cargo bay. These data indicate that payload components can be sensitive to friction induced loads.

  6. Modification of TOUGH2 to Include the Dusty Gas Model for Gas Diffusion; TOPICAL

    International Nuclear Information System (INIS)

    WEBB, STEPHEN W.

    2001-01-01

    The GEO-SEQ Project is investigating methods for geological sequestration of CO(sub 2). This project, which is directed by LBNL and includes a number of other industrial, university, and national laboratory partners, is evaluating computer simulation methods including TOUGH2 for this problem. The TOUGH2 code, which is a widely used code for flow and transport in porous and fractured media, includes simplified methods for gas diffusion based on a direct application of Fick's law. As shown by Webb (1998) and others, the Dusty Gas Model (DGM) is better than Fick's Law for modeling gas-phase diffusion in porous media. In order to improve gas-phase diffusion modeling for the GEO-SEQ Project, the EOS7R module in the TOUGH2 code has been modified to include the Dusty Gas Model as documented in this report. In addition, the liquid diffusion model has been changed from a mass-based formulation to a mole-based model. Modifications for separate and coupled diffusion in the gas and liquid phases have also been completed. The results from the DGM are compared to the Fick's law behavior for TCE and PCE diffusion across a capillary fringe. The differences are small due to the relatively high permeability (k= 10(sup -11) m(sup 2)) of the problem and the small mole fraction of the gases. Additional comparisons for lower permeabilities and higher mole fractions may be useful

  7. Numerical Acoustic Models Including Viscous and Thermal losses: Review of Existing and New Methods

    DEFF Research Database (Denmark)

    Andersen, Peter Risby; Cutanda Henriquez, Vicente; Aage, Niels

    2017-01-01

    This work presents an updated overview of numerical methods including acoustic viscous and thermal losses. Numerical modelling of viscothermal losses has gradually become more important due to the general trend of making acoustic devices smaller. Not including viscothermal acoustic losses...... in such numerical computations will therefore lead to inaccurate or even wrong results. Both, Finite Element Method (FEM) and Boundary Element Method (BEM), formulations are available that incorporate these loss mechanisms. Including viscothermal losses in FEM computations can be computationally very demanding, due...... and BEM method including viscothermal dissipation are compared and investigated....

  8. Direct-phase-variable model of a synchronous reluctance motor including all slot and winding harmonics

    International Nuclear Information System (INIS)

    Obe, Emeka S.; Binder, A.

    2011-01-01

    A detailed model in direct-phase variables of a synchronous reluctance motor operating at mains voltage and frequency is presented. The model includes the stator and rotor slot openings, the actual winding layout and the reluctance rotor geometry. Hence, all mmf and permeance harmonics are taken into account. It is seen that non-negligible harmonics introduced by slots are present in the inductances computed by the winding function procedure. These harmonics are usually ignored in d-q models. The machine performance is simulated in the stator reference frame to depict the difference between this new direct-phase model including all harmonics and the conventional rotor reference frame d-q model. Saturation is included by using a polynomial fitting the variation of d-axis inductance with stator current obtained by finite-element software FEMAG DC (registered) . The detailed phase-variable model can yield torque pulsations comparable to those obtained from finite elements while the d-q model cannot.

  9. Prediction of Broadband Shock-Associated Noise Including Propagation Effects Originating NASA

    Science.gov (United States)

    Miller, Steven; Morris, Philip J.

    2012-01-01

    An acoustic analogy is developed based on the Euler equations for broadband shock-associated noise (BBSAN) that directly incorporates the vector Green s function of the linearized Euler equations and a steady Reynolds-Averaged Navier-Stokes solution (SRANS) to describe the mean flow. The vector Green s function allows the BBSAN propagation through the jet shear layer to be determined. The large-scale coherent turbulence is modeled by two-point second order velocity cross-correlations. Turbulent length and time scales are related to the turbulent kinetic energy and dissipation rate. An adjoint vector Green s function solver is implemented to determine the vector Green s function based on a locally parallel mean flow at different streamwise locations. The newly developed acoustic analogy can be simplified to one that uses the Green s function associated with the Helmholtz equation, which is consistent with a previous formulation by the authors. A large number of predictions are generated using three different nozzles over a wide range of fully-expanded jet Mach numbers and jet stagnation temperatures. These predictions are compared with experimental data from multiple jet noise experimental facilities. In addition, two models for the so-called fine-scale mixing noise are included in the comparisons. Improved BBSAN predictions are obtained relative to other models that do not include propagation effects.

  10. High Bypass Ratio Jet Noise Reduction and Installation Effects Including Shielding Effectiveness

    Science.gov (United States)

    Thomas, Russell H.; Czech, Michael J.; Doty, Michael J.

    2013-01-01

    An experimental investigation was performed to study the propulsion airframe aeroacoustic installation effects of a separate flow jet nozzle with a Hybrid Wing Body aircraft configuration where the engine is installed above the wing. Prior understanding of the jet noise shielding effectiveness was extended to a bypass ratio ten application as a function of nozzle configuration, chevron type, axial spacing, and installation effects from additional airframe components. Chevron types included fan chevrons that are uniform circumferentially around the fan nozzle and T-fan type chevrons that are asymmetrical circumferentially. In isolated testing without a pylon, uniform chevrons compared to T-fan chevrons showed slightly more low frequency reduction offset by more high frequency increase. Phased array localization shows that at this bypass ratio chevrons still move peak jet noise source locations upstream but not to nearly the extent, as a function of frequency, as for lower bypass ratio jets. For baseline nozzles without chevrons, the basic pylon effect has been greatly reduced compared to that seen for lower bypass ratio jets. Compared to Tfan chevrons without a pylon, the combination with a standard pylon results in more high frequency noise increase and an overall higher noise level. Shielded by an airframe surface 2.17 fan diameters from nozzle to airframe trailing edge, the T-fan chevron nozzle can produce reductions in jet noise of as much as 8 dB at high frequencies and upstream angles. Noise reduction from shielding decreases with decreasing frequency and with increasing angle from the jet inlet. Beyond an angle of 130 degrees there is almost no noise reduction from shielding. Increasing chevron immersion more than what is already an aggressive design is not advantageous for noise reduction. The addition of airframe control surfaces, including vertical stabilizers and elevon deflection, showed only a small overall impact. Based on the test results, the best

  11. Clarifying the use of aggregated exposures in multilevel models: self-included vs. self-excluded measures.

    Directory of Open Access Journals (Sweden)

    Etsuji Suzuki

    Full Text Available Multilevel analyses are ideally suited to assess the effects of ecological (higher level and individual (lower level exposure variables simultaneously. In applying such analyses to measures of ecologies in epidemiological studies, individual variables are usually aggregated into the higher level unit. Typically, the aggregated measure includes responses of every individual belonging to that group (i.e. it constitutes a self-included measure. More recently, researchers have developed an aggregate measure which excludes the response of the individual to whom the aggregate measure is linked (i.e. a self-excluded measure. In this study, we clarify the substantive and technical properties of these two measures when they are used as exposures in multilevel models.Although the differences between the two aggregated measures are mathematically subtle, distinguishing between them is important in terms of the specific scientific questions to be addressed. We then show how these measures can be used in two distinct types of multilevel models-self-included model and self-excluded model-and interpret the parameters in each model by imposing hypothetical interventions. The concept is tested on empirical data of workplace social capital and employees' systolic blood pressure.Researchers assume group-level interventions when using a self-included model, and individual-level interventions when using a self-excluded model. Analytical re-parameterizations of these two models highlight their differences in parameter interpretation. Cluster-mean centered self-included models enable researchers to decompose the collective effect into its within- and between-group components. The benefit of cluster-mean centering procedure is further discussed in terms of hypothetical interventions.When investigating the potential roles of aggregated variables, researchers should carefully explore which type of model-self-included or self-excluded-is suitable for a given situation

  12. Clarifying the use of aggregated exposures in multilevel models: self-included vs. self-excluded measures.

    Science.gov (United States)

    Suzuki, Etsuji; Yamamoto, Eiji; Takao, Soshi; Kawachi, Ichiro; Subramanian, S V

    2012-01-01

    Multilevel analyses are ideally suited to assess the effects of ecological (higher level) and individual (lower level) exposure variables simultaneously. In applying such analyses to measures of ecologies in epidemiological studies, individual variables are usually aggregated into the higher level unit. Typically, the aggregated measure includes responses of every individual belonging to that group (i.e. it constitutes a self-included measure). More recently, researchers have developed an aggregate measure which excludes the response of the individual to whom the aggregate measure is linked (i.e. a self-excluded measure). In this study, we clarify the substantive and technical properties of these two measures when they are used as exposures in multilevel models. Although the differences between the two aggregated measures are mathematically subtle, distinguishing between them is important in terms of the specific scientific questions to be addressed. We then show how these measures can be used in two distinct types of multilevel models-self-included model and self-excluded model-and interpret the parameters in each model by imposing hypothetical interventions. The concept is tested on empirical data of workplace social capital and employees' systolic blood pressure. Researchers assume group-level interventions when using a self-included model, and individual-level interventions when using a self-excluded model. Analytical re-parameterizations of these two models highlight their differences in parameter interpretation. Cluster-mean centered self-included models enable researchers to decompose the collective effect into its within- and between-group components. The benefit of cluster-mean centering procedure is further discussed in terms of hypothetical interventions. When investigating the potential roles of aggregated variables, researchers should carefully explore which type of model-self-included or self-excluded-is suitable for a given situation, particularly

  13. A new wall function boundary condition including heat release effect for supersonic combustion flows

    International Nuclear Information System (INIS)

    Gao, Zhen-Xun; Jiang, Chong-Wen; Lee, Chun-Hian

    2016-01-01

    Highlights: • A new wall function including heat release effect is theoretically derived. • The new wall function is a unified form holding for flows with/without combustion. • The new wall function shows good results for a supersonic combustion case. - Abstract: A new wall function boundary condition considering combustion heat release effect (denoted as CWFBC) is proposed, for efficient predictions of skin friction and heat transfer in supersonic combustion flows. Based on a standard flow model including boundary-layer combustion, the Shvab–Zeldovich coupling parameters are introduced to derive a new velocity law-of-the-wall including the influence of combustion. For the temperature law-of-the-wall, it is proposed to use the enthalpy–velocity relation, instead of the Crocco–Busemann equation, to eliminate explicit influence of chemical reactions. The obtained velocity and temperature law-of-the-walls constitute the CWFBC, which is a unified form simultaneously holding for single-species, multi-species mixing and multi-species reactive flows. The subsequent numerical simulations using this CWFBC on an experimental case indicate that the CWFBC could accurately reflect the influences on the skin friction and heat transfer by the chemical reactions and heat release, and show large improvements compared to previous WFBC. Moreover, the CWFBC can give accurate skin friction and heat flux for a coarse mesh with y + up to 200 for the experimental case, except for slightly larger discrepancy of the wall heat flux around ignition position.

  14. The No-Core Gamow Shell Model: Including the continuum in the NCSM

    CERN Document Server

    Barrett, B R; Michel, N; Płoszajczak, M

    2015-01-01

    We are witnessing an era of intense experimental efforts that will provide information about the properties of nuclei far from the line of stability, regarding resonant and scattering states as well as (weakly) bound states. This talk describes our formalism for including these necessary ingredients into the No-Core Shell Model by using the Gamow Shell Model approach. Applications of this new approach, known as the No-Core Gamow Shell Model, both to benchmark cases as well as to unstable nuclei will be given.

  15. Conceptualizing a Dynamic Fall Risk Model Including Intrinsic Risks and Exposures.

    Science.gov (United States)

    Klenk, Jochen; Becker, Clemens; Palumbo, Pierpaolo; Schwickert, Lars; Rapp, Kilan; Helbostad, Jorunn L; Todd, Chris; Lord, Stephen R; Kerse, Ngaire

    2017-11-01

    Falls are a major cause of injury and disability in older people, leading to serious health and social consequences including fractures, poor quality of life, loss of independence, and institutionalization. To design and provide adequate prevention measures, accurate understanding and identification of person's individual fall risk is important. However, to date, the performance of fall risk models is weak compared with models estimating, for example, cardiovascular risk. This deficiency may result from 2 factors. First, current models consider risk factors to be stable for each person and not change over time, an assumption that does not reflect real-life experience. Second, current models do not consider the interplay of individual exposure including type of activity (eg, walking, undertaking transfers) and environmental risks (eg, lighting, floor conditions) in which activity is performed. Therefore, we posit a dynamic fall risk model consisting of intrinsic risk factors that vary over time and exposure (activity in context). eHealth sensor technology (eg, smartphones) begins to enable the continuous measurement of both the above factors. We illustrate our model with examples of real-world falls from the FARSEEING database. This dynamic framework for fall risk adds important aspects that may improve understanding of fall mechanisms, fall risk models, and the development of fall prevention interventions. Copyright © 2017 AMDA – The Society for Post-Acute and Long-Term Care Medicine. Published by Elsevier Inc. All rights reserved.

  16. The Watts-Strogatz network model developed by including degree distribution: theory and computer simulation

    International Nuclear Information System (INIS)

    Chen, Y W; Zhang, L F; Huang, J P

    2007-01-01

    By using theoretical analysis and computer simulations, we develop the Watts-Strogatz network model by including degree distribution, in an attempt to improve the comparison between characteristic path lengths and clustering coefficients predicted by the original Watts-Strogatz network model and those of the real networks with the small-world property. Good agreement between the predictions of the theoretical analysis and those of the computer simulations has been shown. It is found that the developed Watts-Strogatz network model can fit the real small-world networks more satisfactorily. Some other interesting results are also reported by adjusting the parameters in a model degree-distribution function. The developed Watts-Strogatz network model is expected to help in the future analysis of various social problems as well as financial markets with the small-world property

  17. Nonlinear flow model of multiple fractured horizontal wells with stimulated reservoir volume including the quadratic gradient term

    Science.gov (United States)

    Ren, Junjie; Guo, Ping

    2017-11-01

    The real fluid flow in porous media is consistent with the mass conservation which can be described by the nonlinear governing equation including the quadratic gradient term (QGT). However, most of the flow models have been established by ignoring the QGT and little work has been conducted to incorporate the QGT into the flow model of the multiple fractured horizontal (MFH) well with stimulated reservoir volume (SRV). This paper first establishes a semi-analytical model of an MFH well with SRV including the QGT. Introducing the transformed pressure and flow-rate function, the nonlinear model of a point source in a composite system including the QGT is linearized. Then the Laplace transform, principle of superposition, numerical discrete method, Gaussian elimination method and Stehfest numerical inversion are employed to establish and solve the seepage model of the MFH well with SRV. Type curves are plotted and the effects of relevant parameters are analyzed. It is found that the nonlinear effect caused by the QGT can increase the flow capacity of fluid flow and influence the transient pressure positively. The relevant parameters not only have an effect on the type curve but also affect the error in the pressure calculated by the conventional linear model. The proposed model, which is consistent with the mass conservation, reflects the nonlinear process of the real fluid flow, and thus it can be used to obtain more accurate transient pressure of an MFH well with SRV.

  18. Including an ocean carbon cycle model into iLOVECLIM (v1.0)

    NARCIS (Netherlands)

    Bouttes, N.; Roche, D.M.V.A.P.; Mariotti, V.; Bopp, L.

    2015-01-01

    The atmospheric carbon dioxide concentration plays a crucial role in the radiative balance and as such has a strong influence on the evolution of climate. Because of the numerous interactions between climate and the carbon cycle, it is necessary to include a model of the carbon cycle within a

  19. An imprecise Dirichlet model for Bayesian analysis of failure data including right-censored observations

    International Nuclear Information System (INIS)

    Coolen, F.P.A.

    1997-01-01

    This paper is intended to make researchers in reliability theory aware of a recently introduced Bayesian model with imprecise prior distributions for statistical inference on failure data, that can also be considered as a robust Bayesian model. The model consists of a multinomial distribution with Dirichlet priors, making the approach basically nonparametric. New results for the model are presented, related to right-censored observations, where estimation based on this model is closely related to the product-limit estimator, which is an important statistical method to deal with reliability or survival data including right-censored observations. As for the product-limit estimator, the model considered in this paper aims at not using any information other than that provided by observed data, but our model fits into the robust Bayesian context which has the advantage that all inferences can be based on probabilities or expectations, or bounds for probabilities or expectations. The model uses a finite partition of the time-axis, and as such it is also related to life-tables

  20. MEMLS3&a: Microwave Emission Model of Layered Snowpacks adapted to include backscattering

    Directory of Open Access Journals (Sweden)

    M. Proksch

    2015-08-01

    Full Text Available The Microwave Emission Model of Layered Snowpacks (MEMLS was originally developed for microwave emissions of snowpacks in the frequency range 5–100 GHz. It is based on six-flux theory to describe radiative transfer in snow including absorption, multiple volume scattering, radiation trapping due to internal reflection and a combination of coherent and incoherent superposition of reflections between horizontal layer interfaces. Here we introduce MEMLS3&a, an extension of MEMLS, which includes a backscatter model for active microwave remote sensing of snow. The reflectivity is decomposed into diffuse and specular components. Slight undulations of the snow surface are taken into account. The treatment of like- and cross-polarization is accomplished by an empirical splitting parameter q. MEMLS3&a (as well as MEMLS is set up in a way that snow input parameters can be derived by objective measurement methods which avoid fitting procedures of the scattering efficiency of snow, required by several other models. For the validation of the model we have used a combination of active and passive measurements from the NoSREx (Nordic Snow Radar Experiment campaign in Sodankylä, Finland. We find a reasonable agreement between the measurements and simulations, subject to uncertainties in hitherto unmeasured input parameters of the backscatter model. The model is written in Matlab and the code is publicly available for download through the following website: http://www.iapmw.unibe.ch/research/projects/snowtools/memls.html.

  1. Steady-state analysis of activated sludge processes with a settler model including sludge compression.

    Science.gov (United States)

    Diehl, S; Zambrano, J; Carlsson, B

    2016-01-01

    A reduced model of a completely stirred-tank bioreactor coupled to a settling tank with recycle is analyzed in its steady states. In the reactor, the concentrations of one dominant particulate biomass and one soluble substrate component are modelled. While the biomass decay rate is assumed to be constant, growth kinetics can depend on both substrate and biomass concentrations, and optionally model substrate inhibition. Compressive and hindered settling phenomena are included using the Bürger-Diehl settler model, which consists of a partial differential equation. Steady-state solutions of this partial differential equation are obtained from an ordinary differential equation, making steady-state analysis of the entire plant difficult. A key result showing that the ordinary differential equation can be replaced with an approximate algebraic equation simplifies model analysis. This algebraic equation takes the location of the sludge-blanket during normal operation into account, allowing for the limiting flux capacity caused by compressive settling to easily be included in the steady-state mass balance equations for the entire plant system. This novel approach grants the possibility of more realistic solutions than other previously published reduced models, comprised of yet simpler settler assumptions. The steady-state concentrations, solids residence time, and the wastage flow ratio are functions of the recycle ratio. Solutions are shown for various growth kinetics; with different values of biomass decay rate, influent volumetric flow, and substrate concentration. Copyright © 2015 Elsevier Ltd. All rights reserved.

  2. TS Fuzzy Model-Based Controller Design for a Class of Nonlinear Systems Including Nonsmooth Functions

    DEFF Research Database (Denmark)

    Vafamand, Navid; Asemani, Mohammad Hassan; Khayatiyan, Alireza

    2018-01-01

    criterion, new robust controller design conditions in terms of linear matrix inequalities are derived. Three practical case studies, electric power steering system, a helicopter model and servo-mechanical system, are presented to demonstrate the importance of such class of nonlinear systems comprising......This paper proposes a novel robust controller design for a class of nonlinear systems including hard nonlinearity functions. The proposed approach is based on Takagi-Sugeno (TS) fuzzy modeling, nonquadratic Lyapunov function, and nonparallel distributed compensation scheme. In this paper, a novel...... TS modeling of the nonlinear dynamics with signum functions is proposed. This model can exactly represent the original nonlinear system with hard nonlinearity while the discontinuous signum functions are not approximated. Based on the bounded-input-bounded-output stability scheme and L₁ performance...

  3. A roller chain drive model including contact with guide-bars

    DEFF Research Database (Denmark)

    Pedersen, Sine Leergaard; Hansen, John Michael; Ambrósio, J. A. C.

    2004-01-01

    as continuous force. The model of the roller-chain drive now proposed departs from an earlier model where two contact/impact methods are proposed to describe the contact between the rollers of the chain and the teeth of the sprockets. These different formulations are based on unilateral constraints....... In the continuous force method the roller-sprocket contact, is represented by forces applied on each seated roller and in the respective sprocket teeth. These forces are functions of the pseudo penetrations between roller and sprocket, impacting velocities and a restitution coefficient. In the continuous force......A model of a roller chain drive is developed and applied to the simulation and analysis of roller chain drives of large marine diesel engines. The model includes the impact with guide-bars that are the motion delimiter components on the chain strands between the sprockets. The main components...

  4. Prospects for genetically modified non-human primate models, including the common marmoset.

    Science.gov (United States)

    Sasaki, Erika

    2015-04-01

    Genetically modified mice have contributed much to studies in the life sciences. In some research fields, however, mouse models are insufficient for analyzing the molecular mechanisms of pathology or as disease models. Often, genetically modified non-human primate (NHP) models are desired, as they are more similar to human physiology, morphology, and anatomy. Recent progress in studies of the reproductive biology in NHPs has enabled the introduction of exogenous genes into NHP genomes or the alteration of endogenous NHP genes. This review summarizes recent progress in the production of genetically modified NHPs, including the common marmoset, and future perspectives for realizing genetically modified NHP models for use in life sciences research. Copyright © 2015 Elsevier Ireland Ltd and the Japan Neuroscience Society. All rights reserved.

  5. Can a one-layer optical skin model including melanin and inhomogeneously distributed blood explain spatially resolved diffuse reflectance spectra?

    Science.gov (United States)

    Karlsson, Hanna; Pettersson, Anders; Larsson, Marcus; Strömberg, Tomas

    2011-02-01

    Model based analysis of calibrated diffuse reflectance spectroscopy can be used for determining oxygenation and concentration of skin chromophores. This study aimed at assessing the effect of including melanin in addition to hemoglobin (Hb) as chromophores and compensating for inhomogeneously distributed blood (vessel packaging), in a single-layer skin model. Spectra from four humans were collected during different provocations using a twochannel fiber optic probe with source-detector separations 0.4 and 1.2 mm. Absolute calibrated spectra using data from either a single distance or both distances were analyzed using inverse Monte Carlo for light transport and Levenberg-Marquardt for non-linear fitting. The model fitting was excellent using a single distance. However, the estimated model failed to explain spectra from the other distance. The two-distance model did not fit the data well at either distance. Model fitting was significantly improved including melanin and vessel packaging. The most prominent effect when fitting data from the larger separation compared to the smaller separation was a different light scattering decay with wavelength, while the tissue fraction of Hb and saturation were similar. For modeling spectra at both distances, we propose using either a multi-layer skin model or a more advanced model for the scattering phase function.

  6. Global Reference Atmospheric Models, Including Thermospheres, for Mars, Venus and Earth

    Science.gov (United States)

    Justh, Hilary L.; Justus, C. G.; Keller, Vernon W.

    2006-01-01

    This document is the viewgraph slides of the presentation. Marshall Space Flight Center's Natural Environments Branch has developed Global Reference Atmospheric Models (GRAMs) for Mars, Venus, Earth, and other solar system destinations. Mars-GRAM has been widely used for engineering applications including systems design, performance analysis, and operations planning for aerobraking, entry descent and landing, and aerocapture. Preliminary results are presented, comparing Mars-GRAM with measurements from Mars Reconnaissance Orbiter (MRO) during its aerobraking in Mars thermosphere. Venus-GRAM is based on the Committee on Space Research (COSPAR) Venus International Reference Atmosphere (VIRA), and is suitable for similar engineering applications in the thermosphere or other altitude regions of the atmosphere of Venus. Until recently, the thermosphere in Earth-GRAM has been represented by the Marshall Engineering Thermosphere (MET) model. Earth-GRAM has recently been revised. In addition to including an updated version of MET, it now includes an option to use the Naval Research Laboratory Mass Spectrometer Incoherent Scatter Radar Extended Model (NRLMSISE-00) as an alternate thermospheric model. Some characteristics and results from Venus-GRAM and Earth-GRAM thermospheres are also presented.

  7. Path-integral isomorphic Hamiltonian for including nuclear quantum effects in non-adiabatic dynamics

    Science.gov (United States)

    Tao, Xuecheng; Shushkov, Philip; Miller, Thomas F.

    2018-03-01

    We describe a path-integral approach for including nuclear quantum effects in non-adiabatic chemical dynamics simulations. For a general physical system with multiple electronic energy levels, a corresponding isomorphic Hamiltonian is introduced such that Boltzmann sampling of the isomorphic Hamiltonian with classical nuclear degrees of freedom yields the exact quantum Boltzmann distribution for the original physical system. In the limit of a single electronic energy level, the isomorphic Hamiltonian reduces to the familiar cases of either ring polymer molecular dynamics (RPMD) or centroid molecular dynamics Hamiltonians, depending on the implementation. An advantage of the isomorphic Hamiltonian is that it can easily be combined with existing mixed quantum-classical dynamics methods, such as surface hopping or Ehrenfest dynamics, to enable the simulation of electronically non-adiabatic processes with nuclear quantum effects. We present numerical applications of the isomorphic Hamiltonian to model two- and three-level systems, with encouraging results that include improvement upon a previously reported combination of RPMD with surface hopping in the deep-tunneling regime.

  8. Highly accurate spectral retardance characterization of a liquid crystal retarder including Fabry-Perot interference effects

    Energy Technology Data Exchange (ETDEWEB)

    Vargas, Asticio [Departamento de Ciencias Físicas, Universidad de La Frontera, Temuco (Chile); Center for Optics and Photonics, Universidad de Concepción, Casilla 4016, Concepción (Chile); Mar Sánchez-López, María del [Instituto de Bioingeniería, Universidad Miguel Hernández, 03202 Elche (Spain); García-Martínez, Pascuala [Departament d' Òptica, Universitat de València, 45100 Burjassot (Spain); Arias, Julia; Moreno, Ignacio [Departamento de Ciencia de Materiales, Óptica y Tecnología Electrónica, Universidad Miguel Hernández, 03202 Elche (Spain)

    2014-01-21

    Multiple-beam Fabry-Perot (FP) interferences occur in liquid crystal retarders (LCR) devoid of an antireflective coating. In this work, a highly accurate method to obtain the spectral retardance of such devices is presented. On the basis of a simple model of the LCR that includes FP effects and by using a voltage transfer function, we show how the FP features in the transmission spectrum can be used to accurately retrieve the ordinary and extraordinary spectral phase delays, and the voltage dependence of the latter. As a consequence, the modulation characteristics of the device are fully determined with high accuracy by means of a few off-state physical parameters which are wavelength-dependent, and a single voltage transfer function that is valid within the spectral range of characterization.

  9. Transient performances analysis of wind turbine system with induction generator including flux saturation and skin effect

    DEFF Research Database (Denmark)

    Li, H.; Zhao, B.; Han, L.

    2010-01-01

    In order to analyze correctly the effect of different models for induction generators on the transient performances of large wind power generation, Wind turbine driven squirrel cage induction generator (SCIG) models taking into account both main and leakage flux saturation and skin effect were...

  10. The Prediction of Broadband Shock-Associated Noise Including Propagation Effects

    Science.gov (United States)

    Miller, Steven; Morris, Philip J.

    2011-01-01

    An acoustic analogy is developed based on the Euler equations for broadband shock- associated noise (BBSAN) that directly incorporates the vector Green's function of the linearized Euler equations and a steady Reynolds-Averaged Navier-Stokes solution (SRANS) as the mean flow. The vector Green's function allows the BBSAN propagation through the jet shear layer to be determined. The large-scale coherent turbulence is modeled by two-point second order velocity cross-correlations. Turbulent length and time scales are related to the turbulent kinetic energy and dissipation. An adjoint vector Green's function solver is implemented to determine the vector Green's function based on a locally parallel mean flow at streamwise locations of the SRANS solution. However, the developed acoustic analogy could easily be based on any adjoint vector Green's function solver, such as one that makes no assumptions about the mean flow. The newly developed acoustic analogy can be simplified to one that uses the Green's function associated with the Helmholtz equation, which is consistent with the formulation of Morris and Miller (AIAAJ 2010). A large number of predictions are generated using three different nozzles over a wide range of fully expanded Mach numbers and jet stagnation temperatures. These predictions are compared with experimental data from multiple jet noise labs. In addition, two models for the so-called 'fine-scale' mixing noise are included in the comparisons. Improved BBSAN predictions are obtained relative to other models that do not include the propagation effects, especially in the upstream direction of the jet.

  11. Surface potential based modeling of charge, current, and capacitances in DGTFET including mobile channel charge and ambipolar behaviour

    Science.gov (United States)

    Jain, Prateek; Yadav, Chandan; Agarwal, Amit; Chauhan, Yogesh Singh

    2017-08-01

    We present a surface potential based analytical model for double gate tunnel field effect transistor (DGTFET) for the current, terminal charges, and terminal capacitances. The model accounts for the effect of the mobile charge in the channel and captures the device physics in depletion as well as in the strong inversion regime. The narrowing of the tunnel barrier in the presence of mobile charges in the channel is incorporated via modeling of the inverse decay length, which is constant under channel depletion condition and bias dependent under inversion condition. To capture the ambipolar current behavior in the model, tunneling at the drain junction is also included. The proposed model is validated against TCAD simulation data and it shows close match with the simulation data.

  12. Producing high-accuracy lattice models from protein atomic coordinates including side chains.

    Science.gov (United States)

    Mann, Martin; Saunders, Rhodri; Smith, Cameron; Backofen, Rolf; Deane, Charlotte M

    2012-01-01

    Lattice models are a common abstraction used in the study of protein structure, folding, and refinement. They are advantageous because the discretisation of space can make extensive protein evaluations computationally feasible. Various approaches to the protein chain lattice fitting problem have been suggested but only a single backbone-only tool is available currently. We introduce LatFit, a new tool to produce high-accuracy lattice protein models. It generates both backbone-only and backbone-side-chain models in any user defined lattice. LatFit implements a new distance RMSD-optimisation fitting procedure in addition to the known coordinate RMSD method. We tested LatFit's accuracy and speed using a large nonredundant set of high resolution proteins (SCOP database) on three commonly used lattices: 3D cubic, face-centred cubic, and knight's walk. Fitting speed compared favourably to other methods and both backbone-only and backbone-side-chain models show low deviation from the original data (~1.5 Å RMSD in the FCC lattice). To our knowledge this represents the first comprehensive study of lattice quality for on-lattice protein models including side chains while LatFit is the only available tool for such models.

  13. Modeling and analysis of the affinity filtration process, including broth feeding, washing, and elution steps.

    Science.gov (United States)

    He, L Z; Dong, X Y; Sun, Y

    1998-01-01

    Affinity filtration is a developing protein purification technique that combines the high selectivity of affinity chromatography and the high processing speed of membrane filtration. In this work a lumped kinetic model was developed to describe the whole affinity filtration process, including broth feeding, contaminant washing, and elution steps. Affinity filtration experiments were conducted to evaluate the model using bovine serum albumin as a model protein and a highly substituted Blue Sepharose as an affinity adsorbent. The model with nonadjustable parameters agreed fairly to the experimental results. Thus, the performance of the affinity filtration in processing a crude broth containing contaminant proteins was analyzed by computer simulations using the lumped model. The simulation results show that there is an optimal protein loading for obtaining the maximum recovery yield of the desired protein with a constant purity at each operating condition. The concentration of a crude broth is beneficial in increasing the recovery yield of the desired protein. Using a constant amount of the affinity adsorbent, the recovery yield can be enhanced by decreasing the solution volume in the stirred tank due to the increase of the adsorbent weight fraction. It was found that the lumped kinetic model was simple and useful in analyzing the whole affinity filtration process.

  14. COSYMA: Health effects models

    International Nuclear Information System (INIS)

    Ehrhardt, J.

    1995-02-01

    As one of the main objectives of the MARIA project (''Methods for Assessing the Radiological Impact of Accidents'') initiated by the Commission of the European Communities the program package COSYMA (''COde SYstem from MARIA'') for assessing the radiological and economic off-site consequences of accidental releases of radioactive material to the atmosphere has been jointly developed by the Kernforschungszentrum Karlsruhe (KfK), FRG, and the National Radiological Protection Board (NRPB), UK. COSYMA includes models and data for assessing a broad spectrum of accident consequences, and they are implemented in independent modules. The subject of this report are those modules, which incorporate models and data for assessing individual and collective risks for deterministic and stochastic health effects. It describes the models implemented, the mathematical algorithms and the required data. Examples are given and explained for the input and output part of the modules. (orig.)

  15. Model for safety reports including descriptive examples; Mall foer saekerhetsrapporter med beskrivande exempel

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-12-01

    Several safety reports will be produced in the process of planning and constructing the system for disposal of high-level radioactive waste in Sweden. The present report gives a model, with detailed examples, of how these reports should be organized and what steps they should include. In the near future safety reports will deal with the encapsulation plant and the repository. Later reports will treat operation of the handling systems and the repository.

  16. Results of including geometric nonlinearities in an aeroelastic model of an F/A-18

    Science.gov (United States)

    Buttrill, Carey S.

    1989-01-01

    An integrated, nonlinear simulation model suitable for aeroelastic modeling of fixed-wing aircraft has been developed. While the author realizes that the subject of modeling rotating, elastic structures is not closed, it is believed that the equations of motion developed and applied herein are correct to second order and are suitable for use with typical aircraft structures. The equations are not suitable for large elastic deformation. In addition, the modeling framework generalizes both the methods and terminology of non-linear rigid-body airplane simulation and traditional linear aeroelastic modeling. Concerning the importance of angular/elastic inertial coupling in the dynamic analysis of fixed-wing aircraft, the following may be said. The rigorous inclusion of said coupling is not without peril and must be approached with care. In keeping with the same engineering judgment that guided the development of the traditional aeroelastic equations, the effect of non-linear inertial effects for most airplane applications is expected to be small. A parameter does not tell the whole story, however, and modes flagged by the parameter as significant also need to be checked to see if the coupling is not a one-way path, i.e., the inertially affected modes can influence other modes.

  17. Collisional-radiative model including recombination processes for W27+ ion★

    Science.gov (United States)

    Murakami, Izumi; Sasaki, Akira; Kato, Daiji; Koike, Fumihiro

    2017-10-01

    We have constructed a collisional-radiative (CR) model for W27+ ions including 226 configurations with n ≤ 9 and ł ≤ 5 for spectroscopic diagnostics. We newly include recombination processes in the model and this is the first result of extreme ultraviolet spectrum calculated for recombining plasma component. Calculated spectra in 40-70 Å range in ionizing and recombining plasma components show similar 3 strong lines and 1 line weak in recombining plasma component at 45-50 Å and many weak lines at 50-65 Å for both components. Recombination processes do not contribute much to the spectrum at around 60 Å for W27+ ion. Dielectronic satellite lines are also minor contribution to the spectrum of recombining plasma component. Dielectronic recombination (DR) rate coefficient from W28+ to W27+ ions is also calculated with the same atomic data in the CR model. We found that larger set of energy levels including many autoionizing states gave larger DR rate coefficients but our rate agree within factor 6 with other works at electron temperature around 1 keV in which W27+ and W28+ ions are usually observed in plasmas. Contribution to the Topical Issue "Atomic and Molecular Data and their Applications", edited by Gordon W.F. Drake, Jung-Sik Yoon, Daiji Kato, and Grzegorz Karwasz.

  18. The total assessment profile, volume 2. [including societal impact, cost effectiveness, and economic analysis

    Science.gov (United States)

    Leininger, G.; Jutila, S.; King, J.; Muraco, W.; Hansell, J.; Lindeen, J.; Franckowiak, E.; Flaschner, A.

    1975-01-01

    Appendices are presented which include discussions of interest formulas, factors in regionalization, parametric modeling of discounted benefit-sacrifice streams, engineering economic calculations, and product innovation. For Volume 1, see .

  19. Modeling the distribution of ammonia across Europe including bi-directional surface–atmosphere exchange

    Directory of Open Access Journals (Sweden)

    R. J. Wichink Kruit

    2012-12-01

    Full Text Available A large shortcoming of current chemistry transport models (CTM for simulating the fate of ammonia in the atmosphere is the lack of a description of the bi-directional surface–atmosphere exchange. In this paper, results of an update of the surface–atmosphere exchange module DEPAC, i.e. DEPosition of Acidifying Compounds, in the chemistry transport model LOTOS-EUROS are discussed. It is shown that with the new description, which includes bi-directional surface–atmosphere exchange, the modeled ammonia concentrations increase almost everywhere, in particular in agricultural source areas. The reason is that by using a compensation point the ammonia lifetime and transport distance is increased. As a consequence, deposition of ammonia and ammonium decreases in agricultural source areas, while it increases in large nature areas and remote regions especially in southern Scandinavia. The inclusion of a compensation point for water reduces the dry deposition over sea and allows reproducing the observed marine background concentrations at coastal locations to a better extent. A comparison with measurements shows that the model results better represent the measured ammonia concentrations. The concentrations in nature areas are slightly overestimated, while the concentrations in agricultural source areas are still underestimated. Although the introduction of the compensation point improves the model performance, the modeling of ammonia remains challenging. Important aspects are emission patterns in space and time as well as a proper approach to deal with the high concentration gradients in relation to model resolution. In short, the inclusion of a bi-directional surface–atmosphere exchange is a significant step forward for modeling ammonia.

  20. Including policy and management in socio-hydrology models: initial conceptualizations

    Science.gov (United States)

    Hermans, Leon; Korbee, Dorien

    2017-04-01

    Socio-hydrology studies the interactions in coupled human-water systems. So far, the use of dynamic models that capture the direct feedback between societal and hydrological systems has been dominant. What has not yet been included with any particular emphasis, is the policy or management layer, which is a central element in for instance integrated water resources management (IWRM) or adaptive delta management (ADM). Studying the direct interactions between human-water systems generates knowledges that eventually helps influence these interactions in ways that may ensure better outcomes - for society and for the health and sustainability of water systems. This influence sometimes occurs through spontaneous emergence, uncoordinated by societal agents - private sector, citizens, consumers, water users. However, the term 'management' in IWRM and ADM also implies an additional coordinated attempt through various public actors. This contribution is a call to include the policy and management dimension more prominently into the research focus of the socio-hydrology field, and offers first conceptual variables that should be considered in attempts to include this policy or management layer in socio-hydrology models. This is done by drawing on existing frameworks to study policy processes throughout both planning and implementation phases. These include frameworks such as the advocacy coalition framework, collective learning and policy arrangements, which all emphasis longer-term dynamics and feedbacks between actor coalitions in strategic planning and implementation processes. A case about longter-term dynamics in the management of the Haringvliet in the Netherlands is used to illustrate the paper.

  1. Modelling of Water Cooled Fuel Including Design Basis and Severe Accidents. Proceedings of a Technical Meeting

    International Nuclear Information System (INIS)

    2015-11-01

    The demands on nuclear fuel have recently been increasing, and include transient regimes, higher discharge burnup and longer fuel cycles. This has resulted in an increase of loads on fuel and core internals. In order to satisfy these demands while ensuring compliance with safety criteria, new national and international programmes have been launched and advanced modelling codes are being developed. The Fukushima Daiichi accident has particularly demonstrated the need for adequate analysis of all aspects of fuel performance to prevent a failure and also to predict fuel behaviour were an accident to occur.This publication presents the Proceedings of the Technical Meeting on Modelling of Water Cooled Fuel Including Design Basis and Severe Accidents, which was hosted by the Nuclear Power Institute of China (NPIC) in Chengdu, China, following the recommendation made in 2013 at the IAEA Technical Working Group on Fuel Performance and Technology. This recommendation was in agreement with IAEA mid-term initiatives, linked to the post-Fukushima IAEA Nuclear Safety Action Plan, as well as the forthcoming Coordinated Research Project (CRP) on Fuel Modelling in Accident Conditions. At the technical meeting in Chengdu, major areas and physical phenomena, as well as types of code and experiment to be studied and used in the CRP, were discussed. The technical meeting provided a forum for international experts to review the state of the art of code development for modelling fuel performance of nuclear fuel for water cooled reactors with regard to steady state and transient conditions, and for design basis and early phases of severe accidents, including experimental support for code validation. A round table discussion focused on the needs and perspectives on fuel modelling in accident conditions. This meeting was the ninth in a series of IAEA meetings, which reflects Member States’ continuing interest in nuclear fuel issues. The previous meetings were held in 1980 (jointly with

  2. A Simple Model of Fields Including the Strong or Nuclear Force and a Cosmological Speculation

    Directory of Open Access Journals (Sweden)

    David L. Spencer

    2016-10-01

    Full Text Available Reexamining the assumptions underlying the General Theory of Relativity and calling an object's gravitational field its inertia, and acceleration simply resistance to that inertia, yields a simple field model where the potential (kinetic energy of a particle at rest is its capacity to move itself when its inertial field becomes imbalanced. The model then attributes electromagnetic and strong forces to the effects of changes in basic particle shape. Following up on the model's assumption that the relative intensity of a particle's gravitational field is always inversely related to its perceived volume and assuming that all black holes spin, may create the possibility of a cosmic rebound where a final spinning black hole ends with a new Big Bang.

  3. A structural model for the in vivo human cornea including collagen-swelling interaction.

    Science.gov (United States)

    Cheng, Xi; Petsche, Steven J; Pinsky, Peter M

    2015-08-06

    A structural model of the in vivo cornea, which accounts for tissue swelling behaviour, for the three-dimensional organization of stromal fibres and for collagen-swelling interaction, is proposed. Modelled as a binary electrolyte gel in thermodynamic equilibrium, the stromal electrostatic free energy is based on the mean-field approximation. To account for active endothelial ionic transport in the in vivo cornea, which modulates osmotic pressure and hydration, stromal mobile ions are shown to satisfy a modified Boltzmann distribution. The elasticity of the stromal collagen network is modelled based on three-dimensional collagen orientation probability distributions for every point in the stroma obtained by synthesizing X-ray diffraction data for azimuthal angle distributions and second harmonic-generated image processing for inclination angle distributions. The model is implemented in a finite-element framework and employed to predict free and confined swelling of stroma in an ionic bath. For the in vivo cornea, the model is used to predict corneal swelling due to increasing intraocular pressure (IOP) and is adapted to model swelling in Fuchs' corneal dystrophy. The biomechanical response of the in vivo cornea to a typical LASIK surgery for myopia is analysed, including tissue fluid pressure and swelling responses. The model provides a new interpretation of the corneal active hydration control (pump-leak) mechanism based on osmotic pressure modulation. The results also illustrate the structural necessity of fibre inclination in stabilizing the corneal refractive surface with respect to changes in tissue hydration and IOP. © 2015 The Author(s).

  4. Static aeroelastic analysis including geometric nonlinearities based on reduced order model

    Directory of Open Access Journals (Sweden)

    Changchuan Xie

    2017-04-01

    Full Text Available This paper describes a method proposed for modeling large deflection of aircraft in nonlinear aeroelastic analysis by developing reduced order model (ROM. The method is applied for solving the static aeroelastic and static aeroelastic trim problems of flexible aircraft containing geometric nonlinearities; meanwhile, the non-planar effects of aerodynamics and follower force effect have been considered. ROMs are computational inexpensive mathematical representations compared to traditional nonlinear finite element method (FEM especially in aeroelastic solutions. The approach for structure modeling presented here is on the basis of combined modal/finite element (MFE method that characterizes the stiffness nonlinearities and we apply that structure modeling method as ROM to aeroelastic analysis. Moreover, the non-planar aerodynamic force is computed by the non-planar vortex lattice method (VLM. Structure and aerodynamics can be coupled with the surface spline method. The results show that both of the static aeroelastic analysis and trim analysis of aircraft based on structure ROM can achieve a good agreement compared to analysis based on the FEM and experimental result.

  5. A satellite relative motion model including J_2 and J_3 via Vinti's intermediary

    Science.gov (United States)

    Biria, Ashley D.; Russell, Ryan P.

    2018-03-01

    Vinti's potential is revisited for analytical propagation of the main satellite problem, this time in the context of relative motion. A particular version of Vinti's spheroidal method is chosen that is valid for arbitrary elliptical orbits, encapsulating J_2, J_3, and generally a partial J_4 in an orbit propagation theory without recourse to perturbation methods. As a child of Vinti's solution, the proposed relative motion model inherits these properties. Furthermore, the problem is solved in oblate spheroidal elements, leading to large regions of validity for the linearization approximation. After offering several enhancements to Vinti's solution, including boosts in accuracy and removal of some singularities, the proposed model is derived and subsequently reformulated so that Vinti's solution is piecewise differentiable. While the model is valid for the critical inclination and nonsingular in the element space, singularities remain in the linear transformation from Earth-centered inertial coordinates to spheroidal elements when the eccentricity is zero or for nearly equatorial orbits. The new state transition matrix is evaluated against numerical solutions including the J_2 through J_5 terms for a wide range of chief orbits and separation distances. The solution is also compared with side-by-side simulations of the original Gim-Alfriend state transition matrix, which considers the J_2 perturbation. Code for computing the resulting state transition matrix and associated reference frame and coordinate transformations is provided online as supplementary material.

  6. Including fluid shear viscosity in a structural acoustic finite element model using a scalar fluid representation

    Science.gov (United States)

    Cheng, Lei; Li, Yizeng; Grosh, Karl

    2013-01-01

    An approximate boundary condition is developed in this paper to model fluid shear viscosity at boundaries of coupled fluid-structure system. The effect of shear viscosity is approximated by a correction term to the inviscid boundary condition, written in terms of second order in-plane derivatives of pressure. Both thin and thick viscous boundary layer approximations are formulated; the latter subsumes the former. These approximations are used to develop a variational formation, upon which a viscous finite element method (FEM) model is based, requiring only minor modifications to the boundary integral contributions of an existing inviscid FEM model. Since this FEM formulation has only one degree of freedom for pressure, it holds a great computational advantage over the conventional viscous FEM formulation which requires discretization of the full set of linearized Navier-Stokes equations. The results from thick viscous boundary layer approximation are found to be in good agreement with the prediction from a Navier-Stokes model. When applicable, thin viscous boundary layer approximation also gives accurate results with computational simplicity compared to the thick boundary layer formulation. Direct comparison of simulation results using the boundary layer approximations and a full, linearized Navier-Stokes model are made and used to evaluate the accuracy of the approximate technique. Guidelines are given for the parameter ranges over which the accurate application of the thick and thin boundary approximations can be used for a fluid-structure interaction problem. PMID:23729844

  7. Modelling of bypass transition including the pseudolaminar part of the boundary layer

    Energy Technology Data Exchange (ETDEWEB)

    Prihoda, J.; Hlava, T. [Ceska Akademie Ved, Prague (Czech Republic). Inst. of Thermomechanics; Kozel, K. [Ceske Vysoke Uceni Technicke, Prague (Czech Republic). Faculty of Mechanical Engineering

    1999-12-01

    The boundary-layer transition in turbomachinery is accelerated by a number of parameters, especially by the free-stream turbulence. This so-called bypass transition is usually modelled by means of one-equation or two-equation turbulence models based on turbulent viscosity. Using of transport equations for turbulent energy and for dissipation rate in these models is questionable before the onset of the last stage of the transition, i.e. before the formation of turbulent spots. Used approximations of production and turbulent diffusion are the weak points of turbulence models with turbulent viscosity in the pseudolaminar boundary layer, as the Boussinesq assumption on turbulent viscosity is not fulfilled in this part of the boundary layer. In order to obtain a more reliable prediction of the transitional boundary layer, Mayle and Schulz (1997) proposed for the solution of pseudolaminar boundary layer a special `laminar-kinetic-energy` equation based on the analysis of laminar boundary layer in flows with velocity fluctuations. The effect of production and turbulent diffusion on the development of turbulent energy in the pseudolaminar boundary layer was tested using a two-layer turbulence model. (orig.)

  8. Modelling of bypass transition including the pseudolaminar part of the boundary layer

    Energy Technology Data Exchange (ETDEWEB)

    Prihoda, J.; Hlava, T. (Ceska Akademie Ved, Prague (Czech Republic). Inst. of Thermomechanics); Kozel, K. (Ceske Vysoke Uceni Technicke, Prague (Czech Republic). Faculty of Mechanical Engineering)

    1999-01-01

    The boundary-layer transition in turbomachinery is accelerated by a number of parameters, especially by the free-stream turbulence. This so-called bypass transition is usually modelled by means of one-equation or two-equation turbulence models based on turbulent viscosity. Using of transport equations for turbulent energy and for dissipation rate in these models is questionable before the onset of the last stage of the transition, i.e. before the formation of turbulent spots. Used approximations of production and turbulent diffusion are the weak points of turbulence models with turbulent viscosity in the pseudolaminar boundary layer, as the Boussinesq assumption on turbulent viscosity is not fulfilled in this part of the boundary layer. In order to obtain a more reliable prediction of the transitional boundary layer, Mayle and Schulz (1997) proposed for the solution of pseudolaminar boundary layer a special 'laminar-kinetic-energy' equation based on the analysis of laminar boundary layer in flows with velocity fluctuations. The effect of production and turbulent diffusion on the development of turbulent energy in the pseudolaminar boundary layer was tested using a two-layer turbulence model. (orig.)

  9. 76 FR 23812 - Reliability and Continuity of Communications Networks, Including Broadband Technologies; Effects...

    Science.gov (United States)

    2011-04-28

    ...] Reliability and Continuity of Communications Networks, Including Broadband Technologies; Effects on Broadband...: Effects on Broadband Communications Networks of Damage or Failure of Network Equipment or Severe Overload... Docket 10-92 (Effects on Broadband Communications Networks of Damage or Failure of Network Equipment or...

  10. Modeling radiation dosimetry to predict cognitive outcomes in pediatric patients with CNS embryonal tumors including medulloblastoma

    International Nuclear Information System (INIS)

    Merchant, Thomas E.; Kiehna, Erin N.; Li Chenghong; Shukla, Hemant; Sengupta, Saikat; Xiong Xiaoping; Gajjar, Amar; Mulhern, Raymond K.

    2006-01-01

    Purpose: Model the effects of radiation dosimetry on IQ among pediatric patients with central nervous system (CNS) tumors. Methods and Materials: Pediatric patients with CNS embryonal tumors (n = 39) were prospectively evaluated with serial cognitive testing, before and after treatment with postoperative, risk-adapted craniospinal irradiation (CSI) and conformal primary-site irradiation, followed by chemotherapy. Differential dose-volume data for 5 brain volumes (total brain, supratentorial brain, infratentorial brain, and left and right temporal lobes) were correlated with IQ after surgery and at follow-up by use of linear regression. Results: When the dose distribution was partitioned into 2 levels, both had a significantly negative effect on longitudinal IQ across all 5 brain volumes. When the dose distribution was partitioned into 3 levels (low, medium, and high), exposure to the supratentorial brain appeared to have the most significant impact. For most models, each Gy of exposure had a similar effect on IQ decline, regardless of dose level. Conclusions: Our results suggest that radiation dosimetry data from 5 brain volumes can be used to predict decline in longitudinal IQ. Despite measures to reduce radiation dose and treatment volume, the volume that receives the highest dose continues to have the greatest effect, which supports current volume-reduction efforts

  11. General hypothesis and shell model for the synthesis of semiconductor nanotubes, including carbon nanotubes

    Science.gov (United States)

    Mohammad, S. Noor

    2010-09-01

    Semiconductor nanotubes, including carbon nanotubes, have vast potential for new technology development. The fundamental physics and growth kinetics of these nanotubes are still obscured. Various models developed to elucidate the growth suffer from limited applicability. An in-depth investigation of the fundamentals of nanotube growth has, therefore, been carried out. For this investigation, various features of nanotube growth, and the role of the foreign element catalytic agent (FECA) in this growth, have been considered. Observed growth anomalies have been analyzed. Based on this analysis, a new shell model and a general hypothesis have been proposed for the growth. The essential element of the shell model is the seed generated from segregation during growth. The seed structure has been defined, and the formation of droplet from this seed has been described. A modified definition of the droplet exhibiting adhesive properties has also been presented. Various characteristics of the droplet, required for alignment and organization of atoms into tubular forms, have been discussed. Employing the shell model, plausible scenarios for the formation of carbon nanotubes, and the variation in the characteristics of these carbon nanotubes have been articulated. The experimental evidences, for example, for the formation of shell around a core, dipole characteristics of the seed, and the existence of nanopores in the seed, have been presented. They appear to justify the validity of the proposed model. The diversities of nanotube characteristics, fundamentals underlying the creation of bamboo-shaped carbon nanotubes, and the impurity generation on the surface of carbon nanotubes have been elucidated. The catalytic action of FECA on growth has been quantified. The applicability of the proposed model to the nanotube growth by a variety of mechanisms has been elaborated. These mechanisms include the vapor-liquid-solid mechanism, the oxide-assisted growth mechanism, the self

  12. Changes and variations in online and offline communication patterns : Including peer effects

    NARCIS (Netherlands)

    Hage, Eveline; Noseleit, Florian

    2015-01-01

    The impact of online communication on offline communication has received considerable research attention. Yet predominantly single level studies yield conflicting research findings and lack theoretical foundation. This study deviates from previous studies by developing a peer effect model rooted in

  13. A curved multi-component aerosol hygroscopicity model framework: Part 2 – Including organic compounds

    Directory of Open Access Journals (Sweden)

    D. O. Topping

    2005-01-01

    Full Text Available This paper describes the inclusion of organic particulate material within the Aerosol Diameter Dependent Equilibrium Model (ADDEM framework described in the companion paper applied to inorganic aerosol components. The performance of ADDEM is analysed in terms of its capability to reproduce the behaviour of various organic and mixed inorganic/organic systems using recently published bulk data. Within the modelling architecture already described two separate thermodynamic models are coupled in an additive approach and combined with a method for solving the Kohler equation in order to develop a tool for predicting the water content associated with an aerosol of known inorganic/organic composition and dry size. For development of the organic module, the widely used group contribution method UNIFAC is employed to explicitly deal with the non-ideality in solution. The UNIFAC predictions for components of atmospheric importance were improved considerably by using revised interaction parameters derived from electro-dynamic balance studies. Using such parameters, the model was found to adequately describe mixed systems including 5–6 dicarboxylic acids, down to low relative humidity conditions. By comparison with electrodynamic balance data, it was also found that the model was capable of capturing the behaviour of aqueous aerosols containing Suwannee River Fulvic acid, a structure previously used to represent the functionality of complex oxidised macromolecules often found in atmospheric aerosols. The additive approach for modelling mixed inorganic/organic systems worked well for a variety of mixtures. As expected, deviations between model predictions and measurements increase with increasing concentration. Available surface tension models, used in evaluating the Kelvin term, were found to reproduce measured data with varying success. Deviations from experimental data increased with increased organic compound complexity. For components only slightly

  14. A curved multi-component aerosol hygroscopicity model framework: Part 2 Including organic compounds

    Science.gov (United States)

    Topping, D. O.; McFiggans, G. B.; Coe, H.

    2005-05-01

    This paper describes the inclusion of organic particulate material within the Aerosol Diameter Dependent Equilibrium Model (ADDEM) framework described in the companion paper applied to inorganic aerosol components. The performance of ADDEM is analysed in terms of its capability to reproduce the behaviour of various organic and mixed inorganic/organic systems using recently published bulk data. Within the modelling architecture already described two separate thermodynamic models are coupled in an additive approach and combined with a method for solving the Kohler equation in order to develop a tool for predicting the water content associated with an aerosol of known inorganic/organic composition and dry size. For development of the organic module, the widely used group contribution method UNIFAC is employed to explicitly deal with the non-ideality in solution. The UNIFAC predictions for components of atmospheric importance were improved considerably by using revised interaction parameters derived from electro-dynamic balance studies. Using such parameters, the model was found to adequately describe mixed systems including 5-6 dicarboxylic acids, down to low relative humidity conditions. By comparison with electrodynamic balance data, it was also found that the model was capable of capturing the behaviour of aqueous aerosols containing Suwannee River Fulvic acid, a structure previously used to represent the functionality of complex oxidised macromolecules often found in atmospheric aerosols. The additive approach for modelling mixed inorganic/organic systems worked well for a variety of mixtures. As expected, deviations between model predictions and measurements increase with increasing concentration. Available surface tension models, used in evaluating the Kelvin term, were found to reproduce measured data with varying success. Deviations from experimental data increased with increased organic compound complexity. For components only slightly soluble in water

  15. A biologically inspired neural model for visual and proprioceptive integration including sensory training.

    Science.gov (United States)

    Saidi, Maryam; Towhidkhah, Farzad; Gharibzadeh, Shahriar; Lari, Abdolaziz Azizi

    2013-12-01

    Humans perceive the surrounding world by integration of information through different sensory modalities. Earlier models of multisensory integration rely mainly on traditional Bayesian and causal Bayesian inferences for single causal (source) and two causal (for two senses such as visual and auditory systems), respectively. In this paper a new recurrent neural model is presented for integration of visual and proprioceptive information. This model is based on population coding which is able to mimic multisensory integration of neural centers in the human brain. The simulation results agree with those achieved by casual Bayesian inference. The model can also simulate the sensory training process of visual and proprioceptive information in human. Training process in multisensory integration is a point with less attention in the literature before. The effect of proprioceptive training on multisensory perception was investigated through a set of experiments in our previous study. The current study, evaluates the effect of both modalities, i.e., visual and proprioceptive training and compares them with each other through a set of new experiments. In these experiments, the subject was asked to move his/her hand in a circle and estimate its position. The experiments were performed on eight subjects with proprioception training and eight subjects with visual training. Results of the experiments show three important points: (1) visual learning rate is significantly more than that of proprioception; (2) means of visual and proprioceptive errors are decreased by training but statistical analysis shows that this decrement is significant for proprioceptive error and non-significant for visual error, and (3) visual errors in training phase even in the beginning of it, is much less than errors of the main test stage because in the main test, the subject has to focus on two senses. The results of the experiments in this paper is in agreement with the results of the neural model

  16. Empirical Validation of a Thermal Model of a Complex Roof Including Phase Change Materials

    Directory of Open Access Journals (Sweden)

    Stéphane Guichard

    2015-12-01

    Full Text Available This paper deals with the empirical validation of a building thermal model of a complex roof including a phase change material (PCM. A mathematical model dedicated to PCMs based on the heat apparent capacity method was implemented in a multi-zone building simulation code, the aim being to increase the understanding of the thermal behavior of the whole building with PCM technologies. In order to empirically validate the model, the methodology is based both on numerical and experimental studies. A parametric sensitivity analysis was performed and a set of parameters of the thermal model has been identified for optimization. The use of the generic optimization program called GenOpt® coupled to the building simulation code enabled to determine the set of adequate parameters. We first present the empirical validation methodology and main results of previous work. We then give an overview of GenOpt® and its coupling with the building simulation code. Finally, once the optimization results are obtained, comparisons of the thermal predictions with measurements are found to be acceptable and are presented.

  17. Habitability of super-Earth planets around other suns: models including Red Giant Branch evolution.

    Science.gov (United States)

    von Bloh, W; Cuntz, M; Schröder, K-P; Bounama, C; Franck, S

    2009-01-01

    The unexpected diversity of exoplanets includes a growing number of super-Earth planets, i.e., exoplanets with masses of up to several Earth masses and a similar chemical and mineralogical composition as Earth. We present a thermal evolution model for a 10 Earth-mass planet orbiting a star like the Sun. Our model is based on the integrated system approach, which describes the photosynthetic biomass production and takes into account a variety of climatological, biogeochemical, and geodynamical processes. This allows us to identify a so-called photosynthesis-sustaining habitable zone (pHZ), as determined by the limits of biological productivity on the planetary surface. Our model considers solar evolution during the main-sequence stage and along the Red Giant Branch as described by the most recent solar model. We obtain a large set of solutions consistent with the principal possibility of life. The highest likelihood of habitability is found for "water worlds." Only mass-rich water worlds are able to realize pHZ-type habitability beyond the stellar main sequence on the Red Giant Branch.

  18. Analysis of electronic models for solar cells including energy resolved defect densities

    Energy Technology Data Exchange (ETDEWEB)

    Glitzky, Annegret

    2010-07-01

    We introduce an electronic model for solar cells including energy resolved defect densities. The resulting drift-diffusion model corresponds to a generalized van Roosbroeck system with additional source terms coupled with ODEs containing space and energy as parameters for all defect densities. The system has to be considered in heterostructures and with mixed boundary conditions from device simulation. We give a weak formulation of the problem. If the boundary data and the sources are compatible with thermodynamic equilibrium the free energy along solutions decays monotonously. In other cases it may be increasing, but we estimate its growth. We establish boundedness and uniqueness results and prove the existence of a weak solution. This is done by considering a regularized problem, showing its solvability and the boundedness of its solutions independent of the regularization level. (orig.)

  19. Including sugar cane in the agro-ecosystem model ORCHIDEE-STICS

    Science.gov (United States)

    Valade, A.; Vuichard, N.; Ciais, P.; Viovy, N.

    2010-12-01

    With 4 million ha currently grown for ethanol in Brazil only, approximately half the global bioethanol production in 2005 (Smeets 2008), and a devoted land area expected to expand globally in the years to come, sugar cane is at the heart of the biofuel debate. Indeed, ethanol made from biomass is currently the most widespread option for alternative transportation fuels. It was originally promoted as a carbon neutral energy resource that could bring energy independence to countries and local opportunities to farmers, until attention was drawn to its environmental and socio-economical drawbacks. It is still not clear to which extent it is a solution or a contributor to climate change mitigation. Dynamic Global Vegetation models can help address these issues and quantify the potential impacts of biofuels on ecosystems at scales ranging from on-site to global. The global agro-ecosystem model ORCHIDEE describes water, carbon and energy exchanges at the soil-atmosphere interface for a limited number of natural and agricultural vegetation types. In order to integrate agricultural management to the simulations and to capture more accurately the specificity of crops' phenology, ORCHIDEE has been coupled with the agronomical model STICS. The resulting crop-oriented vegetation model ORCHIDEE-STICS has been used so far to simulate temperate crops such as wheat, corn and soybean. As a generic ecosystem model, each grid cell can include several vegetation types with their own phenology and management practices, making it suitable to spatial simulations. Here, ORCHIDEE-STICS is altered to include sugar cane as a new agricultural Plant functional Type, implemented and parametrized using the STICS approach. An on-site calibration and validation is then performed based on biomass and flux chamber measurements in several sites in Australia and variables such as LAI, dry weight, heat fluxes and respiration are used to evaluate the ability of the model to simulate the specific

  20. Numerical models of single- and double-negative metamaterials including viscous and thermal losses

    DEFF Research Database (Denmark)

    Cutanda Henriquez, Vicente; Sánchez-Dehesa, José

    2017-01-01

    Negative index acoustic metamaterials are artificial structures made of subwavelength units arranged in a lattice, whose effective acoustic parameters, bulk modulus and mass density, can be negative. In these materials, sound waves propagate inside the periodic structure, assumed rigid, showing...... extraordinary properties. We are interested in two particular cases: a double-negative metamaterial, where both parameters are negative at some frequencies, and a single-negative metamaterial with negative bulk modulus within a broader frequency band. In previous research involving the double-negative...... detailed understanding on how viscous and thermal losses affect the setups at different frequencies. The modeling of a simpler single-negative metamaterial also broadens this overview. Both setups have been modeled with quadratic BEM meshes. Each sample, scaled at two different sizes, has been represented...

  1. Web-accessible molecular modeling with Rosetta: The Rosetta Online Server that Includes Everyone (ROSIE).

    Science.gov (United States)

    Moretti, Rocco; Lyskov, Sergey; Das, Rhiju; Meiler, Jens; Gray, Jeffrey J

    2018-01-01

    The Rosetta molecular modeling software package provides a large number of experimentally validated tools for modeling and designing proteins, nucleic acids, and other biopolymers, with new protocols being added continually. While freely available to academic users, external usage is limited by the need for expertise in the Unix command line environment. To make Rosetta protocols available to a wider audience, we previously created a web server called Rosetta Online Server that Includes Everyone (ROSIE), which provides a common environment for hosting web-accessible Rosetta protocols. Here we describe a simplification of the ROSIE protocol specification format, one that permits easier implementation of Rosetta protocols. Whereas the previous format required creating multiple separate files in different locations, the new format allows specification of the protocol in a single file. This new, simplified protocol specification has more than doubled the number of Rosetta protocols available under ROSIE. These new applications include pK a determination, lipid accessibility calculation, ribonucleic acid redesign, protein-protein docking, protein-small molecule docking, symmetric docking, antibody docking, cyclic toxin docking, critical binding peptide determination, and mapping small molecule binding sites. ROSIE is freely available to academic users at http://rosie.rosettacommons.org. © 2017 The Protein Society.

  2. Evaluation of European air quality modelled by CAMx including the volatility basis set scheme

    Directory of Open Access Journals (Sweden)

    G. Ciarelli

    2016-08-01

    Full Text Available Four periods of EMEP (European Monitoring and Evaluation Programme intensive measurement campaigns (June 2006, January 2007, September–October 2008 and February–March 2009 were modelled using the regional air quality model CAMx with VBS (volatility basis set approach for the first time in Europe within the framework of the EURODELTA-III model intercomparison exercise. More detailed analysis and sensitivity tests were performed for the period of February–March 2009 and June 2006 to investigate the uncertainties in emissions as well as to improve the modelling of organic aerosol (OA. Model performance for selected gas phase species and PM2.5 was evaluated using the European air quality database AirBase. Sulfur dioxide (SO2 and ozone (O3 were found to be overestimated for all the four periods, with O3 having the largest mean bias during June 2006 and January–February 2007 periods (8.9 pbb and 12.3 ppb mean biases respectively. In contrast, nitrogen dioxide (NO2 and carbon monoxide (CO were found to be underestimated for all the four periods. CAMx reproduced both total concentrations and monthly variations of PM2.5 for all the four periods with average biases ranging from −2.1 to 1.0 µg m−3. Comparisons with AMS (aerosol mass spectrometer measurements at different sites in Europe during February–March 2009 showed that in general the model overpredicts the inorganic aerosol fraction and underpredicts the organic one, such that the good agreement for PM2.5 is partly due to compensation of errors. The effect of the choice of VBS scheme on OA was investigated as well. Two sensitivity tests with volatility distributions based on previous chamber and ambient measurements data were performed. For February–March 2009 the chamber case reduced the total OA concentrations by about 42 % on average. In contrast, a test based on ambient measurement data increased OA concentrations by about 42 % for the same period bringing

  3. Molecular Modeling of Aerospace Polymer Matrices Including Carbon Nanotube-Enhanced Epoxy

    Science.gov (United States)

    Radue, Matthew S.

    -functionalresins) are simulated with embedded CNT to understand how the affinity to nanoparticles affects the mechanical response. Multiscale modeling techniques are then employed to translate the molecular phenomena observed to predict the behavior of realistic composites. The effective stiffness of hybrid composites are predicted for CNT/epoxy composites with randomly oriented CNTs, for CF/CNT/epoxy systems with aligned CFs and randomly oriented CNTs, and for woven CF/CNT/epoxy fabric with randomly oriented CNTs. The results indicate that in the CNT/epoxy systems the epoxy type has a significant influence on the elastic properties. For the CF/CNT/epoxy hybrid composites, the axial modulus is highly influenced by CF concentration, while the transverse modulus is primarily affected by the CNT weight fraction.

  4. A curved multi-component aerosol hygroscopicity model framework: 2 Including organics

    Science.gov (United States)

    Topping, D. O.; McFiggans, G. B.; Coe, H.

    2004-12-01

    This paper describes the inclusion of organic particulate material within the Aerosol Diameter Dependent Equilibrium Model (ADDEM) framework described in the companion paper applied to inorganic aerosol components. The performance of ADDEM is analysed in terms of its capability to reproduce the behaviour of various organic and mixed inorganic/organic systems using recently published bulk data. Within the modelling architecture already described two separate thermodynamic models are coupled in an additive approach and combined with a method for solving the Köhler equation in order to develop a tool for predicting the water content associated with an aerosol of known inorganic/organic composition and dry size. For development of the organic module, the widely used group contribution method UNIFAC is employed to explicitly deal with the non-ideality in solution. The UNIFAC predictions for components of atmospheric importance were improved considerably by using revised interaction parameters derived from electro-dynamic balance studies. Using such parameters, the model was found to adequately describe mixed systems including 5-6 dicarboxylic acids, down to low relative humidity conditions. The additive approach for modelling mixed inorganic/organic systems worked well for a variety of mixtures. As expected, deviations between predicted and measured data increase with increasing concentration. Available surface tension models, used in evaluating the Kelvin term, were found to reproduce measured data with varying success. Deviations from experimental data increased with increased organic compound complexity. For components only slightly soluble in water, significant deviations from measured surface tension depression behaviour were predicted with both model formalisms tested. A Sensitivity analysis showed that such variation is likely to lead to predicted growth factors within the measurement uncertainty for growth factor taken in the sub-saturated regime. Greater

  5. Coupled modeling of land hydrology–regional climate including human carbon emission and water exploitation

    Directory of Open Access Journals (Sweden)

    Zheng-Hui Xie

    2017-06-01

    Full Text Available Carbon emissions and water use are two major kinds of human activities. To reveal whether these two activities can modify the hydrological cycle and climate system in China, we conducted two sets of numerical experiments using regional climate model RegCM4. In the first experiment used to study the climatic responses to human carbon emissions, the model were configured over entire China because the impacts of carbon emissions can be detected across the whole country. Results from the first experiment revealed that near-surface air temperature may significantly increase from 2007 to 2059 at a rate exceeding 0.1 °C per decade in most areas across the country; southwestern and southeastern China also showed increasing trends in summer precipitation, with rates exceeding 10 mm per decade over the same period. In summer, only northern China showed an increasing trend of evapotranspiration, with increase rates ranging from 1 to 5 mm per decade; in winter, increase rates ranging from 1 to 5 mm per decade were observed in most regions. These effects are believed to be caused by global warming from human carbon emissions. In the second experiment used to study the effects of human water use, the model were configured over a limited region—Haihe River Basin in the northern China, because compared with the human carbon emissions, the effects of human water use are much more local and regional, and the Haihe River Basin is the most typical region in China that suffers from both intensive human groundwater exploitation and surface water diversion. We incorporated a scheme of human water regulation into RegCM4 and conducted the second experiment. Model outputs showed that the groundwater table severely declined by ∼10 m in 1971–2000 through human groundwater over-exploitation in the basin; in fact, current conditions are so extreme that even reducing the pumping rate by half cannot eliminate the groundwater depletion cones observed in the area

  6. A Hydrological Concept including Lateral Water Flow Compatible with the Biogeochemical Model ForSAFE

    Directory of Open Access Journals (Sweden)

    Giuliana Zanchi

    2016-03-01

    Full Text Available The study presents a hydrology concept developed to include lateral water flow in the biogeochemical model ForSAFE. The hydrology concept was evaluated against data collected at Svartberget in the Vindeln Research Forest in Northern Sweden. The results show that the new concept allows simulation of a saturated and an unsaturated zone in the soil as well as water flow that reaches the stream comparable to measurements. The most relevant differences compared to streamflow measurements are that the model simulates a higher base flow in winter and lower flow peaks after snowmelt. These differences are mainly caused by the assumptions made to regulate the percolation at the bottom of the simulated soil columns. The capability for simulating lateral flows and a saturated zone in ForSAFE can greatly improve the simulation of chemical exchange in the soil and export of elements from the soil to watercourses. Such a model can help improve the understanding of how environmental changes in the forest landscape will influence chemical loads to surface waters.

  7. Expanded rock blast modeling capabilities of DMC{_}BLAST, including buffer blasting

    Energy Technology Data Exchange (ETDEWEB)

    Preece, D.S. [Sandia National Labs., Albuquerque, NM (United States); Tidman, J.P.; Chung, S.H. [ICI Explosives (Canada)

    1996-12-31

    A discrete element computer program named DMC{_}BLAST (Distinct Motion Code) has been under development since 1987 for modeling rock blasting. This program employs explicit time integration and uses spherical or cylindrical elements that are represented as circles in 2-D. DMC{_}BLAST calculations compare favorably with data from actual bench blasts. The blast modeling capabilities of DMC{_}BLAST have been expanded to include independently dipping geologic layers, top surface, bottom surface and pit floor. The pit can also now be defined using coordinates based on the toe of the bench. A method for modeling decked explosives has been developed which allows accurate treatment of the inert materials (stemming) in the explosive column and approximate treatment of different explosives in the same blasthole. A DMC{_}BLAST user can specify decking through a specific geologic layer with either inert material or a different explosive. Another new feature of DMC{_}BLAST is specification of an uplift angle which is the angle between the normal to the blasthole and a vector defining the direction of explosive loading on particles adjacent to the blasthole. A buffer (choke) blast capability has been added for situations where previously blasted material is adjacent to the free face of the bench preventing any significant lateral motion during the blast.

  8. Recent Progress on Labfit: a Multispectrum Analysis Program for Fitting Lineshapes Including the Htp Model and Temperature Dependence

    Science.gov (United States)

    Cich, Matthew J.; Guillaume, Alexandre; Drouin, Brian; Benner, D. Chris

    2017-06-01

    Multispectrum analysis can be a challenge for a variety of reasons. It can be computationally intensive to fit a proper line shape model especially for high resolution experimental data. Band-wide analyses including many transitions along with interactions, across many pressures and temperatures are essential to accurately model, for example, atmospherically relevant systems. Labfit is a fast multispectrum analysis program originally developed by D. Chris Benner with a text-based interface. More recently at JPL a graphical user interface was developed with the goal of increasing the ease of use but also the number of potential users. The HTP lineshape model has been added to Labfit keeping it up-to-date with community standards. Recent analyses using labfit will be shown to demonstrate its ability to competently handle large experimental datasets, including high order lineshape effects, that are otherwise unmanageable.

  9. Modelling and control of a microgrid including photovoltaic and wind generation

    Science.gov (United States)

    Hussain, Mohammed Touseef

    Extensive increase of distributed generation (DG) penetration and the existence of multiple DG units at distribution level have introduced the notion of micro-grid. This thesis develops a detailed non-linear and small-signal dynamic model of a microgrid that includes PV, wind and conventional small scale generation along with their power electronics interfaces and the filters. The models developed evaluate the amount of generation mix from various DGs for satisfactory steady state operation of the microgrid. In order to understand the interaction of the DGs on microgrid system initially two simpler configurations were considered. The first one consists of microalternator, PV and their electronics, and the second system consists of microalternator and wind system each connected to the power system grid. Nonlinear and linear state space model of each microgrid are developed. Small signal analysis showed that the large participation of PV/wind can drive the microgrid to the brink of unstable region without adequate control. Non-linear simulations are carried out to verify the results obtained through small-signal analysis. The role of the extent of generation mix of a composite microgrid consisting of wind, PV and conventional generation was investigated next. The findings of the smaller systems were verified through nonlinear and small signal modeling. A central supervisory capacitor energy storage controller interfaced through a STATCOM was proposed to monitor and enhance the microgrid operation. The potential of various control inputs to provide additional damping to the system has been evaluated through decomposition techniques. The signals identified to have damping contents were employed to design the supervisory control system. The controller gains were tuned through an optimal pole placement technique. Simulation studies demonstrate that the STATCOM voltage phase angle and PV inverter phase angle were the best inputs for enhanced stability boundaries.

  10. Mathematical modeling of HIV prevention measures including pre-exposure prophylaxis on HIV incidence in South Korea.

    Science.gov (United States)

    Kim, Sun Bean; Yoon, Myoungho; Ku, Nam Su; Kim, Min Hyung; Song, Je Eun; Ahn, Jin Young; Jeong, Su Jin; Kim, Changsoo; Kwon, Hee-Dae; Lee, Jeehyun; Smith, Davey M; Choi, Jun Yong

    2014-01-01

    Multiple prevention measures have the possibility of impacting HIV incidence in South Korea, including early diagnosis, early treatment, and pre-exposure prophylaxis (PrEP). We investigated how each of these interventions could impact the local HIV epidemic, especially among men who have sex with men (MSM), who have become the major risk group in South Korea. A mathematical model was used to estimate the effects of each these interventions on the HIV epidemic in South Korea over the next 40 years, as compared to the current situation. We constructed a mathematical model of HIV infection among MSM in South Korea, dividing the MSM population into seven groups, and simulated the effects of early antiretroviral therapy (ART), early diagnosis, PrEP, and combination interventions on the incidence and prevalence of HIV infection, as compared to the current situation that would be expected without any new prevention measures. Overall, the model suggested that the most effective prevention measure would be PrEP. Even though PrEP effectiveness could be lessened by increased unsafe sex behavior, PrEP use was still more beneficial than the current situation. In the model, early diagnosis of HIV infection was also effectively decreased HIV incidence. However, early ART did not show considerable effectiveness. As expected, it would be most effective if all interventions (PrEP, early diagnosis and early treatment) were implemented together. This model suggests that PrEP and early diagnosis could be a very effective way to reduce HIV incidence in South Korea among MSM.

  11. Description and Application of A Model of Seepage under A Weir Including Mechanical Clogging

    Directory of Open Access Journals (Sweden)

    Sroka Zbigniew

    2014-07-01

    Full Text Available The paper discusses seepage flow under a damming structure (a weir in view of mechanical clogging in a thin layer at the upstream site. It was assumed that in this layer flow may be treated as one-dimensional (perpendicular to the layer, while elsewhere flow was modelled as two-dimensional. The solution in both zones was obtained in the discrete form using the finite element method and the Euler method. The effect of the clogging layer on seepage flow was modelled using the third kind boundary condition. Seepage parameters in the clogging layer were estimated based on laboratory tests conducted by Skolasińska [2006]. Typical problem was taken to provide simulation and indicate how clogging affects the seepage rate and other parameters of the flow. Results showed that clogging at the upstream site has a significant effect on the distribution of seepage velocity and hydraulic gradients. The flow underneath the structure decreases with time, but these changes are relatively slow.

  12. Extending Galactic Habitable Zone Modeling to Include the Emergence of Intelligent Life.

    Science.gov (United States)

    Morrison, Ian S; Gowanlock, Michael G

    2015-08-01

    Previous studies of the galactic habitable zone have been concerned with identifying those regions of the Galaxy that may favor the emergence of complex life. A planet is deemed habitable if it meets a set of assumed criteria for supporting the emergence of such complex life. In this work, we extend the assessment of habitability to consider the potential for life to further evolve to the point of intelligence--termed the propensity for the emergence of intelligent life, φI. We assume φI is strongly influenced by the time durations available for evolutionary processes to proceed undisturbed by the sterilizing effects of nearby supernovae. The times between supernova events provide windows of opportunity for the evolution of intelligence. We developed a model that allows us to analyze these window times to generate a metric for φI, and we examine here the spatial and temporal variation of this metric. Even under the assumption that long time durations are required between sterilizations to allow for the emergence of intelligence, our model suggests that the inner Galaxy provides the greatest number of opportunities for intelligence to arise. This is due to the substantially higher number density of habitable planets in this region, which outweighs the effects of a higher supernova rate in the region. Our model also shows that φI is increasing with time. Intelligent life emerged at approximately the present time at Earth's galactocentric radius, but a similar level of evolutionary opportunity was available in the inner Galaxy more than 2 Gyr ago. Our findings suggest that the inner Galaxy should logically be a prime target region for searches for extraterrestrial intelligence and that any civilizations that may have emerged there are potentially much older than our own.

  13. Renovation and Strengthening of Wooden Beams With CFRP Bands Including the Rheological Effects

    Directory of Open Access Journals (Sweden)

    Kula Krzysztof

    2016-09-01

    Full Text Available The paper presents a work analysis of wooden beams reinforced with glued composite bands from the top and resin inclusions, taking into account the rheology of materials. The paper presents numerical model of the multimaterial beam work including rheological phenomena described by linear equations of viscoelasticity. For the construction of this model one used MES SIMULIA ABAQUS environment in which were prepared its own procedures containing rheological models. The calculation results were compared with the literature data. One has done an analysis of the advisability of the use of CFRP reinforcements bands in terms of rheological phenomena.

  14. Dynamic behavior of a rotating delaminated composite beam including rotary inertia and shear deformation effects

    Directory of Open Access Journals (Sweden)

    Ramazan-Ali Jafari-Talookolaei

    2015-09-01

    Full Text Available A finite element (FE model is developed to study the free vibration of a rotating laminated composite beam with a single delamination. The rotary inertia and shear deformation effects, as well as the bending–extension, bending–twist and extension–twist coupling terms are taken into account in the FE model. Comparison between the numerical results of the present model and the results published in the literature verifies the validity of the present model. Furthermore, the effects of various parameters, such as delamination size and location, fiber orientation, hub radius, material anisotropy and rotating speed, on the vibration of the beam are studied in detail. These results provide useful information in the study of the free vibration of rotating delaminated composite beams.

  15. Analytical linear energy transfer model including secondary particles: calculations along the central axis of the proton pencil beam

    International Nuclear Information System (INIS)

    Marsolat, F; De Marzi, L; Mazal, A; Pouzoulet, F

    2016-01-01

    In proton therapy, the relative biological effectiveness (RBE) depends on various types of parameters such as linear energy transfer (LET). An analytical model for LET calculation exists (Wilkens’ model), but secondary particles are not included in this model. In the present study, we propose a correction factor, L sec , for Wilkens’ model in order to take into account the LET contributions of certain secondary particles. This study includes secondary protons and deuterons, since the effects of these two types of particles can be described by the same RBE-LET relationship. L sec was evaluated by Monte Carlo (MC) simulations using the GATE/GEANT4 platform and was defined by the ratio of the LET d distributions of all protons and deuterons and only primary protons. This method was applied to the innovative Pencil Beam Scanning (PBS) delivery systems and L sec was evaluated along the beam axis. This correction factor indicates the high contribution of secondary particles in the entrance region, with L sec values higher than 1.6 for a 220 MeV clinical pencil beam. MC simulations showed the impact of pencil beam parameters, such as mean initial energy, spot size, and depth in water, on L sec . The variation of L sec with these different parameters was integrated in a polynomial function of the L sec factor in order to obtain a model universally applicable to all PBS delivery systems. The validity of this correction factor applied to Wilkens’ model was verified along the beam axis of various pencil beams in comparison with MC simulations. A good agreement was obtained between the corrected analytical model and the MC calculations, with mean-LET deviations along the beam axis less than 0.05 keV μm −1 . These results demonstrate the efficacy of our new correction of the existing LET model in order to take into account secondary protons and deuterons along the pencil beam axis. (paper)

  16. Intestinal bacterial overgrowth includes potential pathogens in the carbohydrate overload models of equine acute laminitis.

    Science.gov (United States)

    Onishi, Janet C; Park, Joong-Wook; Prado, Julio; Eades, Susan C; Mirza, Mustajab H; Fugaro, Michael N; Häggblom, Max M; Reinemeyer, Craig R

    2012-10-12

    Carbohydrate overload models of equine acute laminitis are used to study the development of lameness. It is hypothesized that a diet-induced shift in cecal bacterial communities contributes to the development of the pro-inflammatory state that progresses to laminar failure. It is proposed that vasoactive amines, protease activators and endotoxin, all bacterial derived bioactive metabolites, play a role in disease development. Questions regarding the oral bioavailability of many of the bacterial derived bioactive metabolites remain. This study evaluates the possibility that a carbohydrate-induced overgrowth of potentially pathogenic cecal bacteria occurs and that bacterial translocation contributes toward the development of the pro-inflammatory state. Two groups of mixed-breed horses were used, those with laminitis induced by cornstarch (n=6) or oligofructan (n=6) and non-laminitic controls (n=8). Cecal fluid and tissue homogenates of extra-intestinal sites including the laminae were used to enumerate Gram-negative and -positive bacteria. Horses that developed Obel grade2 lameness, revealed a significant overgrowth of potentially pathogenic Gram-positive and Gram-negative intestinal bacteria within the cecal fluid. Although colonization of extra-intestinal sites with potentially pathogenic bacteria was not detected, results of this study indicate that cecal/colonic lymphadenopathy and eosinophilia develop in horses progressing to lameness. It is hypothesized that the pro-inflammatory state in carbohydrate overload models of equine acute laminitis is driven by an immune response to the rapid overgrowth of Gram-positive and Gram-negative cecal bacterial communities in the gut. Further equine research is indicated to study the immunological response, involving the lymphatic system that develops in the model. Copyright © 2012 Elsevier B.V. All rights reserved.

  17. Evaluation of plant-wide WWTP control strategies including the effects of filamentous bulking sludge

    DEFF Research Database (Denmark)

    Flores Alsina, Xavier; Comas, J.S.; Rodríguez Roda, I.

    2009-01-01

    Model No. 2 (BSM2). In a second series of simulations the parameters of the secondary settler model in the BSM2 are automatically changed on the basis of an on-line calculated risk of filamentous bulking, in order to mimic the effect of growth of filamentous bacteria in the plant. The results...... concentration in both return and waste flow, less biomass in the bioreactors and a reduction of the TSS removal efficiency. The control alternatives using a TSS controller substantially increase the food to microorganisms (F/M) ratio in the bioreactor, thereby reducing both risk and effects of bulking sludge...

  18. Comparison of lead isotopes with source apportionment models, including SOM, for air particulates

    International Nuclear Information System (INIS)

    Gulson, Brian; Korsch, Michael; Dickson, Bruce; Cohen, David; Mizon, Karen; Michael Davis, J.

    2007-01-01

    We have measured high precision lead isotopes in PM 2.5 particulates from a highly-trafficked site (Mascot) and rural site (Richmond) in the Sydney Basin, New South Wales, Australia to compare with isotopic data from total suspended particulates (TSP) from other sites in the Sydney Basin and evaluate relationships with source fingerprints obtained from multi-element PM 2.5 data. The isotopic data for the period 1998 to 2004 show seasonal peaks and troughs that are more pronounced in the rural site for the PM 2.5 .samples but are consistent with the TSP. The Self Organising Map (SOM) method has been applied to the multi-element PM 2.5 data to evaluate its use in obtaining fingerprints for comparison with standard statistical procedures (ANSTO model). As seasonal effects are also significant for the multi-element data, the SOM modelling is reported as site and season dependent. At the Mascot site, the ANSTO model exhibits decreasing 206 Pb/ 204 Pb ratios with increasing contributions of fingerprints for 'secondary smoke' (industry), 'soil', 'smoke' and 'seaspray'. Similar patterns were shown by SOM winter fingerprints for both sites. At the rural site, there are large isotopic variations but for the majority of samples these are not associated with increased contributions from the main sources with the ANSTO model. For two winter sampling times, there are increased contributions from 'secondary industry', 'smoke', 'soil' and seaspray with one time having a source or sources of Pb similar to that of Mascot. The only positive relationship between increasing 206 Pb/ 204 Pb ratio and source contributions is found at the rural site using the SOM summer fingerprints, both of which show a significant contribution from sulphur. Several of the fingerprints using either model have significant contributions from black carbon (BC) and/or sulphur (S) that probably derive from diesel fuels and industrial sources. Increased contributions from sources with the SOM summer

  19. Dynamic Analysis of Thick Plates Including Deep Beams on Elastic Foundations Using Modified Vlasov Model

    Directory of Open Access Journals (Sweden)

    Korhan Ozgan

    2013-01-01

    Full Text Available Dynamic analysis of foundation plate-beam systems with transverse shear deformation is presented using modified Vlasov foundation model. Finite element formulation of the problem is derived by using an 8-node (PBQ8 finite element based on Mindlin plate theory for the plate and a 2-node Hughes element based on Timoshenko beam theory for the beam. Selective reduced integration technique is used to avoid shear locking problem for the evaluation of the stiffness matrices for both the elements. The effect of beam thickness, the aspect ratio of the plate and subsoil depth on the response of plate-beam-soil system is analyzed. Numerical examples show that the displacement, bending moments and shear forces are changed significantly by adding the beams.

  20. On the modelling of semi-insulating GaAs including surface tension and bulk stresses

    Energy Technology Data Exchange (ETDEWEB)

    Dreyer, W.; Duderstadt, F.

    2004-07-01

    Necessary heat treatment of single crystal semi-insulating Gallium Arsenide (GaAs), which is deployed in micro- and opto- electronic devices, generate undesirable liquid precipitates in the solid phase. The appearance of precipitates is influenced by surface tension at the liquid/solid interface and deviatoric stresses in the solid. The central quantity for the description of the various aspects of phase transitions is the chemical potential, which can be additively decomposed into a chemical and a mechanical part. In particular the calculation of the mechanical part of the chemical potential is of crucial importance. We determine the chemical potential in the framework of the St. Venant-Kirchhoff law which gives an appropriate stress/strain relation for many solids in the small strain regime. We establish criteria, which allow the correct replacement of the St. Venant-Kirchhoff law by the simpler Hooke law. The main objectives of this study are: (i) We develop a thermo-mechanical model that describes diffusion and interface motion, which both are strongly influenced by surface tension effects and deviatoric stresses. (ii) We give an overview and outlook on problems that can be posed and solved within the framework of the model. (iii) We calculate non-standard phase diagrams, i.e. those that take into account surface tension and non-deviatoric stresses, for GaAs above 786 C, and we compare the results with classical phase diagrams without these phenomena. (orig.)

  1. Application of a new combined model including radiological indicators to predict difficult airway in patients undergoing surgery for cervical spondylosis.

    Science.gov (United States)

    Xu, Mao; Li, Xiaoxi; Wang, Jun; Guo, Xiangyang

    2014-01-01

    Airway management is crucial in clinical anesthesia. Many complications associated with airway management result from unexpected difficult airway, but predicting a difficult airway is a major challenge. We investigated the efficacy of a new combined model including radiological indicators to predict difficult airway in patients undergoing surgery for cervical spondylosis, a population with a high incidence of difficult airway. We randomly enrolled 303 patients scheduled for elective surgery for cervical spondylosis at Peking University Third Hospital between August 2012 and March 2013. Preoperatively, patients were evaluated for difficult airway according to a clinical index and parameters on lateral cervical radiographs and magnetic resonance images. Difficult airway was defined as Cormack-Lehane grades III-IV. Logistic regression was used to identify a combined (clinical and radiological) model for difficult airway. A receiver operating characteristic (ROC) curve was used to describe the effectiveness of prediction. We identified three clinical predictive factors using the ROC curve: mouth opening, sternomental distance, and neck mobility. We created a clinical model using three factors: gender, age, and mouth opening, with odds ratios (OR) of 0.370, 1.034, and 0.358, respectively. Using the clinical and radiological parameters, we formulated a combined model with five risk factors: gender, mouth opening, atlanto-occipital gap, the angle from the second to sixth cervical vertebraes in the neutral position, and the angle difference of d (the angle between the laryngeal axis and the epiglottic axis) from the neutral position to extension (OR: 0.107, 0.355, 0.846, 1.057, and 0.952, respectively). The sensitivity and specificity of the combined model were 80.0% and 65.7%, respectively, and the ROC curve confirmed that the combined model was better than any single clinical predictor and the clinical model. The efficacy of the combined model including both clinical and

  2. Predictive simulations and optimization of nanowire field-effect PSA sensors including screening

    KAUST Repository

    Baumgartner, Stefan

    2013-05-03

    We apply our self-consistent PDE model for the electrical response of field-effect sensors to the 3D simulation of nanowire PSA (prostate-specific antigen) sensors. The charge concentration in the biofunctionalized boundary layer at the semiconductor-electrolyte interface is calculated using the propka algorithm, and the screening of the biomolecules by the free ions in the liquid is modeled by a sensitivity factor. This comprehensive approach yields excellent agreement with experimental current-voltage characteristics without any fitting parameters. Having verified the numerical model in this manner, we study the sensitivity of nanowire PSA sensors by changing device parameters, making it possible to optimize the devices and revealing the attributes of the optimal field-effect sensor. © 2013 IOP Publishing Ltd.

  3. A comparison of different ways of including baseline counts in negative binomial models for data from falls prevention trials.

    Science.gov (United States)

    Zheng, Han; Kimber, Alan; Goodwin, Victoria A; Pickering, Ruth M

    2018-01-01

    A common design for a falls prevention trial is to assess falling at baseline, randomize participants into an intervention or control group, and ask them to record the number of falls they experience during a follow-up period of time. This paper addresses how best to include the baseline count in the analysis of the follow-up count of falls in negative binomial (NB) regression. We examine the performance of various approaches in simulated datasets where both counts are generated from a mixed Poisson distribution with shared random subject effect. Including the baseline count after log-transformation as a regressor in NB regression (NB-logged) or as an offset (NB-offset) resulted in greater power than including the untransformed baseline count (NB-unlogged). Cook and Wei's conditional negative binomial (CNB) model replicates the underlying process generating the data. In our motivating dataset, a statistically significant intervention effect resulted from the NB-logged, NB-offset, and CNB models, but not from NB-unlogged, and large, outlying baseline counts were overly influential in NB-unlogged but not in NB-logged. We conclude that there is little to lose by including the log-transformed baseline count in standard NB regression compared to CNB for moderate to larger sized datasets. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  4. Evolution of the continental upper mantle : numerical modelling of thermo-chemical convection including partial melting

    NARCIS (Netherlands)

    de Smet, J.H.

    1999-01-01

    This thesis elaborates on the evolution of the continental upper mantle based on numerical modelling results. The descriptive and explanatory basis is formed by a numerical thermo-chemical convection model. The model evolution starts in the early Archaean about 4 billion years ago. The model follows

  5. Evolution of the continental upper mantle : numerical modelling of thermo-chemical convection including partial melting

    NARCIS (Netherlands)

    Smet, J.H. de

    1999-01-01

    This thesis elaborates on the evolution of the continental upper mantle based on numerical modelling results. The descriptive and explanatory basis is formed by a numerical thermo-chemical convection model. The model evolution starts in the early Archaean about 4 billion years ago. The model

  6. A Thermal Evolution Model of the Earth Including the Biosphere, Continental Growth and Mantle Hydration

    Science.gov (United States)

    Höning, D.; Spohn, T.

    2014-12-01

    By harvesting solar energy and converting it to chemical energy, photosynthetic life plays an important role in the energy budget of Earth [2]. This leads to alterations of chemical reservoirs eventually affecting the Earth's interior [4]. It further has been speculated [3] that the formation of continents may be a consequence of the evolution life. A steady state model [1] suggests that the Earth without its biosphere would evolve to a steady state with a smaller continent coverage and a dryer mantle than is observed today. We present a model including (i) parameterized thermal evolution, (ii) continental growth and destruction, and (iii) mantle water regassing and outgassing. The biosphere enhances the production rate of sediments which eventually are subducted. These sediments are assumed to (i) carry water to depth bound in stable mineral phases and (ii) have the potential to suppress shallow dewatering of the underlying sediments and crust due to their low permeability. We run a Monte Carlo simulation for various initial conditions and treat all those parameter combinations as success which result in the fraction of continental crust coverage observed for present day Earth. Finally, we simulate the evolution of an abiotic Earth using the same set of parameters but a reduced rate of continental weathering and erosion. Our results suggest that the origin and evolution of life could have stabilized the large continental surface area of the Earth and its wet mantle, leading to the relatively low mantle viscosity we observe at present. Without photosynthetic life on our planet, the Earth would be geodynamical less active due to a dryer mantle, and would have a smaller fraction of continental coverage than observed today. References[1] Höning, D., Hansen-Goos, H., Airo, A., Spohn, T., 2014. Biotic vs. abiotic Earth: A model for mantle hydration and continental coverage. Planetary and Space Science 98, 5-13. [2] Kleidon, A., 2010. Life, hierarchy, and the

  7. One Dimensional Analysis Model of a Condensing Spray Chamber Including Rocket Exhaust Using SINDA/FLUINT and CEA

    Science.gov (United States)

    Sakowski, Barbara; Edwards, Daryl; Dickens, Kevin

    2014-01-01

    Modeling droplet condensation via CFD codes can be very tedious, time consuming, and inaccurate. CFD codes may be tedious and time consuming in terms of using Lagrangian particle tracking approaches or particle sizing bins. Also since many codes ignore conduction through the droplet and or the degradating effect of heat and mass transfer if noncondensible species are present, the solutions may be inaccurate. The modeling of a condensing spray chamber where the significant size of the water droplets and the time and distance these droplets take to fall, can make the effect of droplet conduction a physical factor that needs to be considered in the model. Furthermore the presence of even a relatively small amount of noncondensible has been shown to reduce the amount of condensation [Ref 1]. It is desirable then to create a modeling tool that addresses these issues. The path taken to create such a tool is illustrated. The application of this tool and subsequent results are based on the spray chamber in the Spacecraft Propulsion Research Facility (B2) located at NASA's Plum Brook Station that tested an RL-10 engine. The platform upon which the condensation physics is modeled is SINDAFLUINT. The use of SINDAFLUINT enables the ability to model various aspects of the entire testing facility, including the rocket exhaust duct flow and heat transfer to the exhaust duct wall. The ejector pumping system of the spray chamber is also easily implemented via SINDAFLUINT. The goal is to create a transient one dimensional flow and heat transfer model beginning at the rocket, continuing through the condensing spray chamber, and finally ending with the ejector pumping system. However the model of the condensing spray chamber may be run independently of the rocket and ejector systems detail, with only appropriate mass flow boundary conditions placed at the entrance and exit of the condensing spray chamber model. The model of the condensing spray chamber takes into account droplet

  8. A phantom model demonstration of tomotherapy dose painting delivery, including managed respiratory motion without motion management

    Energy Technology Data Exchange (ETDEWEB)

    Kissick, Michael W; Mo Xiaohu; McCall, Keisha C; Mackie, Thomas R [Department of Medical Physics, Wisconsin Institutes for Medical Research, 111 Highland Avenue, University of Wisconsin-Madison, Madison, WI 53705 (United States); Schubert, Leah K [Radiation Oncology Department, University of Nebraska Medical Center, Omaha, NE 68198 (United States); Westerly, David C, E-mail: mwkissick@wisc.ed [Department of Radiation Oncology, University of Colorado Denver, Aurora, CO 80045 (United States)

    2010-05-21

    The aim of the study was to demonstrate a potential alternative scenario for accurate dose-painting (non-homogeneous planned dose) delivery at 1 cm beam width with helical tomotherapy (HT) in the presence of 1 cm, three-dimensional, intra-fraction respiratory motion, but without any active motion management. A model dose-painting experiment was planned and delivered to the average position (proper phase of a 4DCT scan) with three spherical PTV levels to approximate dose painting to compensate for hypothetical hypoxia in a model lung tumor. Realistic but regular motion was produced with the Washington University 4D Motion Phantom. A small spherical Virtual Water(TM) phantom was used to simulate a moving lung tumor inside of the LUNGMAN(TM) anthropomorphic chest phantom to simulate realistic heterogeneity uncertainties. A piece of 4 cm Gafchromic EBT(TM) film was inserted into the 6 cm diameter sphere. TomoTherapy, Inc., DQA(TM) software was used to verify the delivery performed on a TomoTherapy Hi-Art II(TM) device. The dose uncertainty in the purposeful absence of motion management and in the absence of large, low frequency drifts (periods greater than the beam width divided by the couch velocity) or randomness in the breathing displacement yields very favorable results. Instead of interference effects, only small blurring is observed because of the averaging of many breathing cycles and beamlets and the avoidance of interference. Dose painting during respiration with helical tomotherapy is feasible in certain situations without motion management. A simple recommendation is to make respiration as regular as possible without low frequency drifting. The blurring is just small enough to suggest that it may be acceptable to deliver without motion management if the motion is equal to the beam width or smaller (at respiration frequencies) when registered to the average position.

  9. A phantom model demonstration of tomotherapy dose painting delivery, including managed respiratory motion without motion management

    International Nuclear Information System (INIS)

    Kissick, Michael W; Mo Xiaohu; McCall, Keisha C; Mackie, Thomas R; Schubert, Leah K; Westerly, David C

    2010-01-01

    The aim of the study was to demonstrate a potential alternative scenario for accurate dose-painting (non-homogeneous planned dose) delivery at 1 cm beam width with helical tomotherapy (HT) in the presence of 1 cm, three-dimensional, intra-fraction respiratory motion, but without any active motion management. A model dose-painting experiment was planned and delivered to the average position (proper phase of a 4DCT scan) with three spherical PTV levels to approximate dose painting to compensate for hypothetical hypoxia in a model lung tumor. Realistic but regular motion was produced with the Washington University 4D Motion Phantom. A small spherical Virtual Water(TM) phantom was used to simulate a moving lung tumor inside of the LUNGMAN(TM) anthropomorphic chest phantom to simulate realistic heterogeneity uncertainties. A piece of 4 cm Gafchromic EBT(TM) film was inserted into the 6 cm diameter sphere. TomoTherapy, Inc., DQA(TM) software was used to verify the delivery performed on a TomoTherapy Hi-Art II(TM) device. The dose uncertainty in the purposeful absence of motion management and in the absence of large, low frequency drifts (periods greater than the beam width divided by the couch velocity) or randomness in the breathing displacement yields very favorable results. Instead of interference effects, only small blurring is observed because of the averaging of many breathing cycles and beamlets and the avoidance of interference. Dose painting during respiration with helical tomotherapy is feasible in certain situations without motion management. A simple recommendation is to make respiration as regular as possible without low frequency drifting. The blurring is just small enough to suggest that it may be acceptable to deliver without motion management if the motion is equal to the beam width or smaller (at respiration frequencies) when registered to the average position.

  10. Regional modelling of future African climate north of 15S including greenhouse warming and land degradation

    Energy Technology Data Exchange (ETDEWEB)

    Paeth, H. [Geographical Institute, University of Wuerzburg, Am Hubland, 97074 Wuerzburg (Germany); Thamm, H.P. [Geographical Institute, University of Bonn, Bonn (Germany)

    2007-08-15

    Previous studies have highlighted the crucial role of land degradation in tropical African climate. This effect urgently has to be taken into account when predicting future African climate under enhanced greenhouse conditions. Here, we present time slice experiments of African climate until 2025, using a high-resolution regional climate model. A supposable scenario of future land use changes, involving vegetation loss and soil degradation, is prescribed simultaneously with increasing greenhouse-gas concentrations in order to detect, where the different forcings counterbalance or reinforce each other. This proceeding allows us to define the regions of highest vulnerability with respect to future freshwater availability and food security in tropical and subtropical Africa and may provide a decision basis for political measures. The model simulates a considerable reduction in precipitation amount until 2025 over most of tropical Africa, amounting to partly more than 500 mm (20-40% of the annual sum), particularly in the Congo Basin and the Sahel Zone. The change is strongest in boreal summer and basically reflects the pattern of maximum vegetation cover during the seasonal cycle. The related change in the surface energy fluxes induces a substantial near-surface warming by up to 7C. According to the modified temperature gradients over tropical Africa, the summer monsoon circulation intensifies and transports more humid air masses into the southern part of West Africa. This humidifying effect is overcompensated by a remarkable decrease in surface evaporation, leading to the overall drying tendency over most of Africa. Extreme daily rainfall events become stronger in autumn but less intense in spring. Summer and autumn appear to be characterized by more severe heat waves over Subsaharan West Africa. In addition, the Tropical Easterly Jet is weakening, leading to enhanced drought conditions in the Sahel Zone. All these results suggest that the local impact of land

  11. Approach to include load sequence effects in the design of an offshore wind turbine substructure

    NARCIS (Netherlands)

    Dragt, R.C.; Allaix, D.L.; Maljaars, J.; Tuitman, J.T.; Salman, Y.; Otheguy, M.E.

    2017-01-01

    Fatigue is one of the main design drivers for offshore wind substructures. Using Fracture Mechanics methods, load sequence effects such as crack growth retardation due to large load peaks can be included in the fatigue damage estimation. Due to the sequence dependency, a method is required that

  12. Bending of I-beam with the transvers shear effect included – FEM calculated

    Energy Technology Data Exchange (ETDEWEB)

    Grygorowicz, Magdalena; Lewiński, Jerzy [Poznan University of Technology, Institute of Applied Mechanics ul. Jana Pawła II No. 24, 60-138 Poznań POLAND (Poland)

    2016-06-08

    The paper is devoted to three-point bending of an I-beam with include of transvers shear effect. Numerical calculations were conducted independently with the use of the SolidWorks system and the multi-purpose software package ANSYS The results of FEM study conducted with the use of two systems were compared and presented in tables and figures.

  13. Spectral interferometry including the effect of transparent thin films to measure distances and displacements

    International Nuclear Information System (INIS)

    Hlubina, P.

    2004-01-01

    A spectral-domain interferometric technique is applied for measuring mirror distances and displacements in a dispersive Michelson interferometer when the effect of transparent thin films coated onto the interferometer beam splitter and compensator is known. We employ a low-resolution spectrometer in two experiments with different amounts of dispersion in a Michelson interferometer that includes fused-silica optical sample. Knowing the thickness of the optical sample and the nonlinear phase function of the thin films, the positions of the interferometer mirror are determined precisely by a least-squares fitting of the theoretical spectral interferograms to the recorded ones. We compare the results of the processing that include and do not include the effect of transparent thin films (Author)

  14. Effect of including liquid vinasse in the diet of rabbits on growth performance

    Directory of Open Access Journals (Sweden)

    Maria Cristina de Oliveira

    2013-04-01

    Full Text Available The effects of liquid vinasse (LV in the diet for growing rabbits on performance, carcass yield and intestinal morphometry were assessed. Eighty New Zealand white rabbits were used in a randomized block design with five treatments (LV inclusion at 0, 25, 50, 75 and 100 g/kg diet and four replications. There was no effect of the treatment on final weight, daily weight gain, mortality rate and carcass yield characteristics. The daily intakes of feed, dry matter, crude protein and energy and feed conversion decreased linearly with increase in LV in the diet. Including LV affected the duodenum crypt depth and the ilium villus perimeter and height linearly and affected the duodenum villus perimeter, height and the absorption surfaces and ilium crypt depth and absorption surface quadratically. There was no effect of including LV on jejunum morphometry. Vinasse can be used to feed growing rabbits at up to 87.8 g per kilogram of diet.

  15. Optimization of piezoelectric cantilever energy harvesters including non-linear effects

    International Nuclear Information System (INIS)

    Patel, R; McWilliam, S; Popov, A A

    2014-01-01

    This paper proposes a versatile non-linear model for predicting piezoelectric energy harvester performance. The presented model includes (i) material non-linearity, for both substrate and piezoelectric layers, and (ii) geometric non-linearity incorporated by assuming inextensibility and accurately representing beam curvature. The addition of a sub-model, which utilizes the transfer matrix method to predict eigenfrequencies and eigenvectors for segmented beams, allows for accurate optimization of piezoelectric layer coverage. A validation of the overall theoretical model is performed through experimental testing on both uniform and non-uniform samples manufactured in-house. For the harvester composition used in this work, the magnitude of material non-linearity exhibited by the piezoelectric layer is 35 times greater than that of the substrate layer. It is also observed that material non-linearity, responsible for reductions in resonant frequency with increases in base acceleration, is dominant over geometric non-linearity for standard piezoelectric harvesting devices. Finally, over the tested range, energy loss due to damping is found to increase in a quasi-linear fashion with base acceleration. During an optimization study on piezoelectric layer coverage, results from the developed model were compared with those from a linear model. Unbiased comparisons between harvesters were realized by using devices with identical natural frequencies—created by adjusting the device substrate thickness. Results from three studies, each with a different assumption on mechanical damping variations, are presented. Findings showed that, depending on damping variation, a non-linear model is essential for such optimization studies with each model predicting vastly differing optimum configurations. (paper)

  16. Including Overweight or Obese Students in Physical Education: A Social Ecological Constraint Model

    Science.gov (United States)

    Li, Weidong; Rukavina, Paul

    2012-01-01

    In this review, we propose a social ecological constraint model to study inclusion of overweight or obese students in physical education by integrating key concepts and assumptions from ecological constraint theory in motor development and social ecological models in health promotion and behavior. The social ecological constraint model proposes…

  17. ETM documentation update – including modelling conventions and manual for software tools

    DEFF Research Database (Denmark)

    Grohnheit, Poul Erik

    , it summarises the work done during 2013, and it also contains presentations for promotion of fusion as a future element in the electricity generation mix and presentations for the modelling community concerning model development and model documentation – in particular for TIAM collaboration workshops....

  18. Serverification of Molecular Modeling Applications: The Rosetta Online Server That Includes Everyone (ROSIE)

    Science.gov (United States)

    Conchúir, Shane Ó.; Der, Bryan S.; Drew, Kevin; Kuroda, Daisuke; Xu, Jianqing; Weitzner, Brian D.; Renfrew, P. Douglas; Sripakdeevong, Parin; Borgo, Benjamin; Havranek, James J.; Kuhlman, Brian; Kortemme, Tanja; Bonneau, Richard; Gray, Jeffrey J.; Das, Rhiju

    2013-01-01

    The Rosetta molecular modeling software package provides experimentally tested and rapidly evolving tools for the 3D structure prediction and high-resolution design of proteins, nucleic acids, and a growing number of non-natural polymers. Despite its free availability to academic users and improving documentation, use of Rosetta has largely remained confined to developers and their immediate collaborators due to the code’s difficulty of use, the requirement for large computational resources, and the unavailability of servers for most of the Rosetta applications. Here, we present a unified web framework for Rosetta applications called ROSIE (Rosetta Online Server that Includes Everyone). ROSIE provides (a) a common user interface for Rosetta protocols, (b) a stable application programming interface for developers to add additional protocols, (c) a flexible back-end to allow leveraging of computer cluster resources shared by RosettaCommons member institutions, and (d) centralized administration by the RosettaCommons to ensure continuous maintenance. This paper describes the ROSIE server infrastructure, a step-by-step ‘serverification’ protocol for use by Rosetta developers, and the deployment of the first nine ROSIE applications by six separate developer teams: Docking, RNA de novo, ERRASER, Antibody, Sequence Tolerance, Supercharge, Beta peptide design, NCBB design, and VIP redesign. As illustrated by the number and diversity of these applications, ROSIE offers a general and speedy paradigm for serverification of Rosetta applications that incurs negligible cost to developers and lowers barriers to Rosetta use for the broader biological community. ROSIE is available at http://rosie.rosettacommons.org. PMID:23717507

  19. Microwave effective surface impedance of structures including a high-Tc superconducting film

    International Nuclear Information System (INIS)

    Hartemann, P.

    1992-01-01

    The microwave effective surface impedances of different stacks made of high-temperature superconducting films, dielectric materials and bulk normal metals were computed. The calculations were based on the two-fluid model of superconductors and the conventional transmission line theory. These effective impedances are compared to the calculated intrinsic surface impedances of the stacked superconducting films. The considered superconducting material has been the oxide YBa 2 Cu 3 O 7 epitaxially grown on crystalline substrates (MgO, LaAlO 3 , SrTiO 3 ), the film thickness ranging from a few nm to 1μm. Discrepancies between the effective surface resistances or reactances and the corresponding intrinsic values were determined at 10 GHz for non resonant or resonant structures. At resonance the surface resistance discrepancy exhibits a sharp peak which reaches 10 4 or more in relative value according to the geometry and the used materials. Obviously the effective surface reactance shows also huge variations about the resonance and may be negative. Moreover geometries allowing to obtain an effective resistance smaller than the film intrinsic value have been found. The effects of the resonance phenomenon on the electromagnetic wave reflectivity and reflection phase shift are investigated. Therefore the reported theoretical results demonstrate that the effective surface impedance of YBCO films with a thickness smaller than 500 nm can be very different from the intrinsic film impedance according to the structures. (Author). 3 refs., 10 figs., 2 tabs

  20. Thermodynamic Analysis of TEG-TEC Device Including Influence of Thomson Effect

    Science.gov (United States)

    Feng, Yuanli; Chen, Lingen; Meng, Fankai; Sun, Fengrui

    2018-01-01

    A thermodynamic model of a thermoelectric cooler driven by thermoelectric generator (TEG-TEC) device is established considering Thomson effect. The performance is analyzed and optimized using numerical calculation based on non-equilibrium thermodynamic theory. The influence characteristics of Thomson effect on the optimal performance and variable selection are investigated by comparing the condition with and without Thomson effect. The results show that Thomson effect degrades the performance of TEG-TEC device, it decreases the cooling capacity by 27 %, decreases the coefficient of performance (COP) by 19 %, decreases the maximum cooling temperature difference by 11 % when the ratio of thermoelectric elements number is 0.6, the cold junction temperature of thermoelectric cooler (TEC) is 285 K and the hot junction temperature of thermoelectric generator (TEG) is 450 K. Thomson effect degrades the optimal performance of TEG-TEC device, it decreases the maximum cooling capacity by 28 % and decreases the maximum COP by 28 % under the same junction temperatures. Thomson effect narrows the optimal variable range and optimal working range. In the design of the devices, limited-number thermoelectric elements should be more allocated appropriately to TEG when consider Thomson effect. The results may provide some guidelines for the design of TEG-TEC devices.

  1. Relationship of sea level muon charge ratio to primary composition including nuclear target effects

    Science.gov (United States)

    Goned, A.; Shalaby, M.; Salem, A. M.; Roushdy, M.

    1985-01-01

    The discrepancy between the muon charge ratio observed at low energies and that calculated using pp data is removed by including nuclear target effects. Calculations at high energies show that the primary iron spectrum is expected to change slope from 2 to 2.2 to 2.4 to 2.5 for energies approx. 4 x 10 to the 3 GeV/nucleon if scaling features continue to the highest energies.

  2. A model for firm-specific strategic wisdom : including illustrations and 49 guiding questions

    NARCIS (Netherlands)

    van Straten, Roeland Peter

    2017-01-01

    This PhD thesis provides an answer to the question ‘How may one think strategically’. It does so by presenting a new prescriptive ‘Model for Firm-Specific Strategic Wisdom’. This Model aims to guide any individual strategist in his or her thinking from a state of firm-specific ‘ignorance’ to a state

  3. Complete Loss and Thermal Model of Power Semiconductors Including Device Rating Information

    DEFF Research Database (Denmark)

    Ma, Ke; Bahman, Amir Sajjad; Beczkowski, Szymon

    2015-01-01

    models, only the electrical loadings are focused and treated as design variables, while the device rating is normally pre-defined by experience with limited design flexibility. Consequently, a more complete loss and thermal model is proposed in this paper, which takes into account not only the electrical...

  4. Numerical models of single- and double-negative metamaterials including viscous and thermal losses

    DEFF Research Database (Denmark)

    Cutanda Henriquez, Vicente; Sánchez-Dehesa, José

    2017-01-01

    detailed understanding on how viscous and thermal losses affect the setups at different frequencies. The modeling of a simpler single-negative metamaterial also broadens this overview. Both setups have been modeled with quadratic BEM meshes. Each sample, scaled at two different sizes, has been represented...

  5. PTAC: a computer program for pressure-transient analysis, including the effects of cavitation. [LMFBR

    Energy Technology Data Exchange (ETDEWEB)

    Kot, C A; Youngdahl, C K

    1978-09-01

    PTAC was developed to predict pressure transients in nuclear-power-plant piping systems in which the possibility of cavitation must be considered. The program performs linear or nonlinear fluid-hammer calculations, using a fixed-grid method-of-characteristics solution procedure. In addition to pipe friction and elasticity, the program can treat a variety of flow components, pipe junctions, and boundary conditions, including arbitrary pressure sources and a sodium/water reaction. Essential features of transient cavitation are modeled by a modified column-separation technique. Comparisons of calculated results with available experimental data, for a simple piping arrangement, show good agreement and provide validation of the computational cavitation model. Calculations for a variety of piping networks, containing either liquid sodium or water, demonstrate the versatility of PTAC and clearly show that neglecting cavitation leads to erroneous predictions of pressure-time histories.

  6. Gasification of biomass in a fixed bed downdraft gasifier--a realistic model including tar.

    Science.gov (United States)

    Barman, Niladri Sekhar; Ghosh, Sudip; De, Sudipta

    2012-03-01

    This study presents a model for fixed bed downdraft biomass gasifiers considering tar also as one of the gasification products. A representative tar composition along with its mole fractions, as available in the literature was used as an input parameter within the model. The study used an equilibrium approach for the applicable gasification reactions and also considered possible deviations from equilibrium to further upgrade the equilibrium model to validate a range of reported experimental results. Heat balance was applied to predict the gasification temperature and the predicted values were compared with reported results in literature. A comparative study was made with some reference models available in the literature and also with experimental results reported in the literature. Finally a predicted variation of performance of the gasifier by this validated model for different air-fuel ratio and moisture content was also discussed. Copyright © 2011 Elsevier Ltd. All rights reserved.

  7. Design and modeling of an advanced marine machinery system including waste heat recovery and removal of sulphur oxides

    DEFF Research Database (Denmark)

    Frimann Nielsen, Rasmus; Haglind, Fredrik; Larsen, Ulrik

    2014-01-01

    the efficiency of machinery systems. The wet sulphuric acid process is an effective way of removing flue gas sulphur oxides from land-based coal-fired power plants. Moreover, organic Rankine cycles (ORC) are suitable for heat to power conversion for low temperature heat sources. This paper describes the design...... and modeling of a highly efficient machinery system which includes the removal of exhaust gas sulphur oxides. The system consists of a two-stroke diesel engine, the wet sulphuric process for sulphur removal, a conventional steam Rankine cycle and an ORC. Results of numerical modeling efforts suggest...... that an ORC placed after the conventional waste heat recovery system is able to extract the sulphuric acid from the exhaust gas, while at the same time increase the combined cycle thermal efficiency by 2.6%. The findings indicate that the technology has potential in marine applications regarding both energy...

  8. A viscoplastic model including anisotropic damage for the time dependent behaviour of rock

    Science.gov (United States)

    Pellet, F.; Hajdu, A.; Deleruyelle, F.; Besnus, F.

    2005-08-01

    This paper presents a new constitutive model for the time dependent mechanical behaviour of rock which takes into account both viscoplastic behaviour and evolution of damage with respect to time. This model is built by associating a viscoplastic constitutive law to the damage theory. The main characteristics of this model are the account of a viscoplastic volumetric strain (i.e. contractancy and dilatancy) as well as the anisotropy of damage. The latter is described by a second rank tensor. Using this model, it is possible to predict delayed rupture by determining time to failure, in creep tests for example. The identification of the model parameters is based on experiments such as creep tests, relaxation tests and quasi-static tests. The physical meaning of these parameters is discussed and comparisons with lab tests are presented. The ability of the model to reproduce the delayed failure observed in tertiary creep is demonstrated as well as the sensitivity of the mechanical response to the rate of loading. The model could be used to simulate the evolution of the excavated damage zone around underground openings.

  9. Potential transformation of trace species including aircraft exhaust in a cloud environment. The `Chedrom model`

    Energy Technology Data Exchange (ETDEWEB)

    Ozolin, Y.E.; Karol, I.L. [Main Geophysical Observatory, St. Petersburg (Russian Federation); Ramaroson, R. [Office National d`Etudes et de Recherches Aerospatiales (ONERA), 92 - Chatillon (France)

    1997-12-31

    Box model for coupled gaseous and aqueous phases is used for sensitivity study of potential transformation of trace gases in a cloud environment. The rate of this transformation decreases with decreasing of pH in droplets, with decreasing of photodissociation rates inside the cloud and with increasing of the droplet size. Model calculations show the potential formation of H{sub 2}O{sub 2} in aqueous phase and transformation of gaseous HNO{sub 3} into NO{sub x} in a cloud. This model is applied for exploration of aircraft exhausts evolution in plume inside a cloud. (author) 10 refs.

  10. A Two-Account Life Insurance Model for Scenario-Based Valuation Including Event Risk

    DEFF Research Database (Denmark)

    Jensen, Ninna Reitzel; Schomacker, Kristian Juul

    2015-01-01

    Using a two-account model with event risk, we model life insurance contracts taking into account both guaranteed and non-guaranteed payments in participating life insurance as well as in unit-linked insurance. Here, event risk is used as a generic term for life insurance events, such as death......, disability, etc. In our treatment of participating life insurance, we have special focus on the bonus schemes “consolidation” and “additional benefits”, and one goal is to formalize how these work and interact. Another goal is to describe similarities and differences between participating life insurance...... and unit-linked insurance. By use of a two-account model, we are able to illustrate general concepts without making the model too abstract. To allow for complicated financial markets without dramatically increasing the mathematical complexity, we focus on economic scenarios. We illustrate the use of our...

  11. A Lumped Thermal Model Including Thermal Coupling and Thermal Boundary Conditions for High Power IGBT Modules

    DEFF Research Database (Denmark)

    Bahman, Amir Sajjad; Ma, Ke; Blaabjerg, Frede

    2018-01-01

    Detailed thermal dynamics of high power IGBT modules are important information for the reliability analysis and thermal design of power electronic systems. However, the existing thermal models have their limits to correctly predict these complicated thermal behavior in the IGBTs: The typically used...... thermal model based on one-dimensional RC lumps have limits to provide temperature distributions inside the device, moreover some variable factors in the real-field applications like the cooling and heating conditions of the converter cannot be adapted. On the other hand, the more advanced three......-dimensional thermal models based on Finite Element Method (FEM) need massive computations, which make the long-term thermal dynamics difficult to calculate. In this paper, a new lumped three-dimensional thermal model is proposed, which can be easily characterized from FEM simulations and can acquire the critical...

  12. Advanced Modeling of Ramp Operations including Departure Status at Secondary Airports, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — This project addresses three modeling elements relevant to NASA's IADS research and ATD-2 project, two related to ramp operations at primary airports and one related...

  13. Extending the Scope of the Acculturation/Pidginization Model to Include Cognition.

    Science.gov (United States)

    Schumann, John H.

    1990-01-01

    Examines five cognitive models for second-language acquisition (SLA) and assesses how each might account for the Pidginized interlanguage found in the early stages of second-language acquisition. (23 references) (JL)

  14. An integrated computable general equilibrium model including multiple types and uses of water

    OpenAIRE

    Luckmann, Jonas Jens

    2015-01-01

    Water is a scarce resource in many regions of the world and competition for water is an increasing problem. To countervail this trend policies are needed regulating supply and demand for water. As water is used in many economic activities, water related management decisions usually have complex implications. Economic simulation models have been proven useful to ex-ante assess the consequences of policy changes. Specifically, Computable General Equilibrium (CGE) models are very suitable to ana...

  15. A comprehensive approach to the design of ethanol supply chains including carbon trading effects.

    Science.gov (United States)

    Giarola, Sara; Shah, Nilay; Bezzo, Fabrizio

    2012-03-01

    The optimal design of biofuels production systems is a key component in the analysis of the environmental and economic performance of new sustainable transport systems. In this paper a general mixed integer linear programming modelling framework is developed to assess the design and planning of a multi-period and multi-echelon bioethanol upstream supply chain under market uncertainty. The optimisation design process of biofuels production systems aims at selecting the best biomass and technologies options among several alternatives according to economic and environmental (global warming potential) performance. A key feature in the proposed approach is the acknowledgement of an economic value to the overall GHG emissions, which is implemented through an emissions allowances trading scheme. The future Italian biomass-based ethanol production is adopted as a case study. Results show the effectiveness of the model as a decision making-tool to steer long-term decisions and investments. Copyright © 2011 Elsevier Ltd. All rights reserved.

  16. Including sugar cane in the agro-ecosystem model ORCHIDEE-STICS: calibration and validation

    Science.gov (United States)

    Valade, A.; Vuichard, N.; Ciais, P.; Viovy, N.

    2011-12-01

    Sugarcane is currently the most efficient bioenergy crop with regards to the energy produced per hectare. With approximately half the global bioethanol production in 2005, and a devoted land area expected to expand globally in the years to come, sugar cane is at the heart of the biofuel debate. Dynamic global vegetation models coupled with agronomical models are powerful and novel tools to tackle many of the environmental issues related to biofuels if they are carefully calibrated and validated against field observations. Here we adapt the agro-terrestrial model ORCHIDEE-STICS for sugar cane simulations. Observation data of LAI are used to evaluate the sensitivity of the model to parameters of nitrogen absorption and phenology, which are calibrated in a systematic way for six sites in Australia and La Reunion. We find that the optimal set of parameters is highly dependent on the sites' characteristics and that the model can reproduce satisfactorily the evolution of LAI. This careful calibration of ORCHIDEE-STICS for sugar cane biomass production for different locations and technical itineraries provides a strong basis for further analysis of the impacts of bioenergy-related land use change on carbon cycle budgets. As a next step, a sensitivity analysis is carried out to estimate the uncertainty of the model in biomass and carbon flux simulation due to its parameterization.

  17. Simplification and Validation of a Spectral-Tensor Model for Turbulence Including Atmospheric Stability

    Science.gov (United States)

    Chougule, Abhijit; Mann, Jakob; Kelly, Mark; Larsen, Gunner C.

    2018-02-01

    A spectral-tensor model of non-neutral, atmospheric-boundary-layer turbulence is evaluated using Eulerian statistics from single-point measurements of the wind speed and temperature at heights up to 100 m, assuming constant vertical gradients of mean wind speed and temperature. The model has been previously described in terms of the dissipation rate ɛ , the length scale of energy-containing eddies L , a turbulence anisotropy parameter Γ, the Richardson number Ri, and the normalized rate of destruction of temperature variance η _θ ≡ ɛ _θ /ɛ . Here, the latter two parameters are collapsed into a single atmospheric stability parameter z / L using Monin-Obukhov similarity theory, where z is the height above the Earth's surface, and L is the Obukhov length corresponding to Ri,η _θ. Model outputs of the one-dimensional velocity spectra, as well as cospectra of the streamwise and/or vertical velocity components, and/or temperature, and cross-spectra for the spatial separation of all three velocity components and temperature, are compared with measurements. As a function of the four model parameters, spectra and cospectra are reproduced quite well, but horizontal temperature fluxes are slightly underestimated in stable conditions. In moderately unstable stratification, our model reproduces spectra only up to a scale ˜ 1 km. The model also overestimates coherences for vertical separations, but is less severe in unstable than in stable cases.

  18. A Novel Mean-Value Model of the Cardiovascular System Including a Left Ventricular Assist Device.

    Science.gov (United States)

    Ochsner, Gregor; Amacher, Raffael; Schmid Daners, Marianne

    2017-06-01

    Time-varying elastance models (TVEMs) are often used for simulation studies of the cardiovascular system with a left ventricular assist device (LVAD). Because these models are computationally expensive, they cannot be used for long-term simulation studies. In addition, their equilibria are periodic solutions, which prevent the extraction of a linear time-invariant model that could be used e.g. for the design of a physiological controller. In the current paper, we present a new type of model to overcome these problems: the mean-value model (MVM). The MVM captures the behavior of the cardiovascular system by representative mean values that do not change within the cardiac cycle. For this purpose, each time-varying element is manually converted to its mean-value counterpart. We compare the derived MVM to a similar TVEM in two simulation experiments. In both cases, the MVM is able to fully capture the inter-cycle dynamics of the TVEM. We hope that the new MVM will become a useful tool for researchers working on physiological control algorithms. This paper provides a plant model that enables for the first time the use of tools from classical control theory in the field of physiological LVAD control.

  19. North American Natural Gas Supply Forecast: The Hubbert Method Including the Effects of Institutions

    OpenAIRE

    Reynolds, Douglas B.; Kolodziej, Marek

    2009-01-01

    In this article, the U.S. and southern Canadian natural gas supply market is considered. An important model for oil and natural gas supply is the Hubbert curve. Not all regions of the world are producing oil or natural gas following a Hubbert curve, even when price and market conditions are accounted for. One reason is that institutions are affecting supply. We investigate the possible effects of oil and gas market institutions in North America on natural gas supply. A multi-cycle Hubbert cur...

  20. Including crystal structure attributes in machine learning models of formation energies via Voronoi tessellations

    Science.gov (United States)

    Ward, Logan; Liu, Ruoqian; Krishna, Amar; Hegde, Vinay I.; Agrawal, Ankit; Choudhary, Alok; Wolverton, Chris

    2017-07-01

    While high-throughput density functional theory (DFT) has become a prevalent tool for materials discovery, it is limited by the relatively large computational cost. In this paper, we explore using DFT data from high-throughput calculations to create faster, surrogate models with machine learning (ML) that can be used to guide new searches. Our method works by using decision tree models to map DFT-calculated formation enthalpies to a set of attributes consisting of two distinct types: (i) composition-dependent attributes of elemental properties (as have been used in previous ML models of DFT formation energies), combined with (ii) attributes derived from the Voronoi tessellation of the compound's crystal structure. The ML models created using this method have half the cross-validation error and similar training and evaluation speeds to models created with the Coulomb matrix and partial radial distribution function methods. For a dataset of 435 000 formation energies taken from the Open Quantum Materials Database (OQMD), our model achieves a mean absolute error of 80 meV/atom in cross validation, which is lower than the approximate error between DFT-computed and experimentally measured formation enthalpies and below 15% of the mean absolute deviation of the training set. We also demonstrate that our method can accurately estimate the formation energy of materials outside of the training set and be used to identify materials with especially large formation enthalpies. We propose that our models can be used to accelerate the discovery of new materials by identifying the most promising materials to study with DFT at little additional computational cost.

  1. Including shielding effects in application of the TPCA method for detection of embedded radiation sources.

    Energy Technology Data Exchange (ETDEWEB)

    Johnson, William C.; Shokair, Isaac R.

    2011-12-01

    Conventional full spectrum gamma spectroscopic analysis has the objective of quantitative identification of all the radionuclides present in a measurement. For low-energy resolution detectors such as NaI, when photopeaks alone are not sufficient for complete isotopic identification, such analysis requires template spectra for all the radionuclides present in the measurement. When many radionuclides are present it is difficult to make the correct identification and this process often requires many attempts to obtain a statistically valid solution by highly skilled spectroscopists. A previous report investigated using the targeted principal component analysis method (TPCA) for detection of embedded sources for RPM applications. This method uses spatial/temporal information from multiple spectral measurements to test the hypothesis of the presence of a target spectrum of interest in these measurements without the need to identify all the other radionuclides present. The previous analysis showed that the TPCA method has significant potential for automated detection of target radionuclides of interest, but did not include the effects of shielding. This report complements the previous analysis by including the effects of spectral distortion due to shielding effects for the same problem of detection of embedded sources. Two examples, one with one target radionuclide and the other with two, show that the TPCA method can successfully detect shielded targets in the presence of many other radionuclides. The shielding parameters are determined as part of the optimization process using interpolation of library spectra that are defined on a 2D grid of atomic numbers and areal densities.

  2. Kinetic modelling of anaerobic hydrolysis of solid wastes, including disintegration processes

    Energy Technology Data Exchange (ETDEWEB)

    García-Gen, Santiago [Department of Chemical Engineering, Institute of Technology, University of Santiago de Compostela, 15782 Santiago de Compostela (Spain); Sousbie, Philippe; Rangaraj, Ganesh [INRA, UR50, Laboratoire de Biotechnologie de l’Environnement, Avenue des Etangs, Narbonne F-11100 (France); Lema, Juan M. [Department of Chemical Engineering, Institute of Technology, University of Santiago de Compostela, 15782 Santiago de Compostela (Spain); Rodríguez, Jorge, E-mail: jrodriguez@masdar.ac.ae [Department of Chemical Engineering, Institute of Technology, University of Santiago de Compostela, 15782 Santiago de Compostela (Spain); Institute Centre for Water and Environment (iWater), Masdar Institute of Science and Technology, PO Box 54224 Abu Dhabi (United Arab Emirates); Steyer, Jean-Philippe; Torrijos, Michel [INRA, UR50, Laboratoire de Biotechnologie de l’Environnement, Avenue des Etangs, Narbonne F-11100 (France)

    2015-01-15

    Highlights: • Fractionation of solid wastes into readily and slowly biodegradable fractions. • Kinetic coefficients estimation from mono-digestion batch assays. • Validation of kinetic coefficients with a co-digestion continuous experiment. • Simulation of batch and continuous experiments with an ADM1-based model. - Abstract: A methodology to estimate disintegration and hydrolysis kinetic parameters of solid wastes and validate an ADM1-based anaerobic co-digestion model is presented. Kinetic parameters of the model were calibrated from batch reactor experiments treating individually fruit and vegetable wastes (among other residues) following a new protocol for batch tests. In addition, decoupled disintegration kinetics for readily and slowly biodegradable fractions of solid wastes was considered. Calibrated parameters from batch assays of individual substrates were used to validate the model for a semi-continuous co-digestion operation treating simultaneously 5 fruit and vegetable wastes. The semi-continuous experiment was carried out in a lab-scale CSTR reactor for 15 weeks at organic loading rate ranging between 2.0 and 4.7 g VS/L d. The model (built in Matlab/Simulink) fit to a large extent the experimental results in both batch and semi-continuous mode and served as a powerful tool to simulate the digestion or co-digestion of solid wastes.

  3. HIV Model Parameter Estimates from Interruption Trial Data including Drug Efficacy and Reservoir Dynamics

    Science.gov (United States)

    Luo, Rutao; Piovoso, Michael J.; Martinez-Picado, Javier; Zurakowski, Ryan

    2012-01-01

    Mathematical models based on ordinary differential equations (ODE) have had significant impact on understanding HIV disease dynamics and optimizing patient treatment. A model that characterizes the essential disease dynamics can be used for prediction only if the model parameters are identifiable from clinical data. Most previous parameter identification studies for HIV have used sparsely sampled data from the decay phase following the introduction of therapy. In this paper, model parameters are identified from frequently sampled viral-load data taken from ten patients enrolled in the previously published AutoVac HAART interruption study, providing between 69 and 114 viral load measurements from 3–5 phases of viral decay and rebound for each patient. This dataset is considerably larger than those used in previously published parameter estimation studies. Furthermore, the measurements come from two separate experimental conditions, which allows for the direct estimation of drug efficacy and reservoir contribution rates, two parameters that cannot be identified from decay-phase data alone. A Markov-Chain Monte-Carlo method is used to estimate the model parameter values, with initial estimates obtained using nonlinear least-squares methods. The posterior distributions of the parameter estimates are reported and compared for all patients. PMID:22815727

  4. A Model for the Design of Puzzle-Based Games Including Virtual and Physical Objects

    Science.gov (United States)

    Melero, Javier; Hernandez-Leo, Davinia

    2014-01-01

    Multiple evidences in the Technology-Enhanced Learning domain indicate that Game-Based Learning can lead to positive effects in students' performance and motivation. Educational games can be completely virtual or can combine the use of physical objects or spaces in the real world. However, the potential effectiveness of these approaches…

  5. Modeling of the dynamics of wind to power conversion including high wind speed behavior

    DEFF Research Database (Denmark)

    Litong-Palima, Marisciel; Bjerge, Martin Huus; Cutululis, Nicolaos Antonio

    2016-01-01

    This paper proposes and validates an efficient, generic and computationally simple dynamic model for the conversion of the wind speed at hub height into the electrical power by a wind turbine. This proposed wind turbine model was developed as a first step to simulate wind power time series...... speed shutdowns and restarts are represented as on–off switching rules that govern the output of the wind turbine at extreme wind speed conditions. The model uses the concept of equivalent wind speed, estimated from the single point (hub height) wind speed using a second-order dynamic filter...... measurements available from the DONG Energy offshore wind farm Horns Rev 2. Copyright © 2015 John Wiley & Sons, Ltd....

  6. An extended TRANSCAR model including ionospheric convection: simulation of EISCAT observations using inputs from AMIE

    Directory of Open Access Journals (Sweden)

    P.-L. Blelly

    2005-02-01

    Full Text Available The TRANSCAR ionospheric model was extended to account for the convection of the magnetic field lines in the auroral and polar ionosphere. A mixed Eulerian-Lagrangian 13-moment approach was used to describe the dynamics of an ionospheric plasma tube. In the present study, one focuses on large scale transports in the polar ionosphere. The model was used to simulate a 35-h period of EISCAT-UHF observations on 16-17 February 1993. The first day was magnetically quiet, and characterized by elevated electron concentrations: the diurnal F2 layer reached as much as 1012m-3, which is unusual for a winter and moderate solar activity (F10.7=130 period. An intense geomagnetic event occurred on the second day, seen in the data as a strong intensification of the ionosphere convection velocities in the early afternoon (with the northward electric field reaching 150mVm-1 and corresponding frictional heating of the ions up to 2500K. The simulation used time-dependent AMIE outputs to infer flux-tube transports in the polar region, and to provide magnetospheric particle and energy inputs to the ionosphere. The overall very good agreement, obtained between the model and the observations, demonstrates the high ability of the extended TRANSCAR model for quantitative modelling of the high-latitude ionosphere; however, some differences are found which are attributed to the precipitation of electrons with very low energy. All these results are finally discussed in the frame of modelling the auroral ionosphere with space weather applications in mind.

  7. An extended TRANSCAR model including ionospheric convection: simulation of EISCAT observations using inputs from AMIE

    Directory of Open Access Journals (Sweden)

    P.-L. Blelly

    2005-02-01

    Full Text Available The TRANSCAR ionospheric model was extended to account for the convection of the magnetic field lines in the auroral and polar ionosphere. A mixed Eulerian-Lagrangian 13-moment approach was used to describe the dynamics of an ionospheric plasma tube. In the present study, one focuses on large scale transports in the polar ionosphere. The model was used to simulate a 35-h period of EISCAT-UHF observations on 16-17 February 1993. The first day was magnetically quiet, and characterized by elevated electron concentrations: the diurnal F2 layer reached as much as 1012m-3, which is unusual for a winter and moderate solar activity (F10.7=130 period. An intense geomagnetic event occurred on the second day, seen in the data as a strong intensification of the ionosphere convection velocities in the early afternoon (with the northward electric field reaching 150mVm-1 and corresponding frictional heating of the ions up to 2500K. The simulation used time-dependent AMIE outputs to infer flux-tube transports in the polar region, and to provide magnetospheric particle and energy inputs to the ionosphere. The overall very good agreement, obtained between the model and the observations, demonstrates the high ability of the extended TRANSCAR model for quantitative modelling of the high-latitude ionosphere; however, some differences are found which are attributed to the precipitation of electrons with very low energy. All these results are finally discussed in the frame of modelling the auroral ionosphere with space weather applications in mind.

  8. Modelling of safety barriers including human and organisational factors to improve process safety

    DEFF Research Database (Denmark)

    Markert, Frank; Duijm, Nijs Jan; Thommesen, Jacob

    2013-01-01

    Assessment Methodology for IndustrieS, see Salvi et al 2006). ARAMIS employs the bow-tie approach to modelling hazardous scenarios, and it suggests the outcome of auditing safety management to be connected to a semi-quantitative assessment of the quality of safety barriers. ARAMIS discriminates a number...... of safety barrier (passive, automated, or involving human action). Such models are valuable for many purposes, but are difficult to apply to more complex situations, as the influences are to be set individually for each barrier. The approach described in this paper is trying to improve the state...

  9. Laboratory Studies of the Reactive Chemistry and Changing CCN Properties of Secondary Organic Aerosol, Including Model Development

    Energy Technology Data Exchange (ETDEWEB)

    Scot Martin

    2013-01-31

    The chemical evolution of secondary-organic-aerosol (SOA) particles and how this evolution alters their cloud-nucleating properties were studied. Simplified forms of full Koehler theory were targeted, specifically forms that contain only those aspects essential to describing the laboratory observations, because of the requirement to minimize computational burden for use in integrated climate and chemistry models. The associated data analysis and interpretation have therefore focused on model development in the framework of modified kappa-Koehler theory. Kappa is a single parameter describing effective hygroscopicity, grouping together several separate physicochemical parameters (e.g., molar volume, surface tension, and van't Hoff factor) that otherwise must be tracked and evaluated in an iterative full-Koehler equation in a large-scale model. A major finding of the project was that secondary organic materials produced by the oxidation of a range of biogenic volatile organic compounds for diverse conditions have kappa values bracketed in the range of 0.10 +/- 0.05. In these same experiments, somewhat incongruently there was significant chemical variation in the secondary organic material, especially oxidation state, as was indicated by changes in the particle mass spectra. Taken together, these findings then support the use of kappa as a simplified yet accurate general parameter to represent the CCN activation of secondary organic material in large-scale atmospheric and climate models, thereby greatly reducing the computational burden while simultaneously including the most recent mechanistic findings of laboratory studies.

  10. Non-kinematic Flux-transport Dynamos Including the Effects of Diffusivity Quenching

    Energy Technology Data Exchange (ETDEWEB)

    Ichimura, Chiaki; Yokoyama, Takaaki [Department of Earth and Planetary Science, The University of Tokyo, Hongo, Bunkyo-ku, Tokyo 113-0033 (Japan)

    2017-04-10

    Turbulent magnetic diffusivity is quenched when strong magnetic fields suppress turbulent motion in a phenomenon known as diffusivity quenching. Diffusivity quenching can provide a mechanism for amplifying magnetic field and influencing global velocity fields through Lorentz force feedback. To investigate this effect, we conducted mean field flux-transport dynamo simulations that included the effects of diffusivity quenching in a non-kinematic regime. We found that toroidal magnetic field strength is amplified by up to approximately 1.5 times in the convection zone as a result of diffusivity quenching. This amplification is much weaker than that in kinematic cases as a result of Lorentz force feedback on the system’s differential rotation. While amplified toroidal fields lead to the suppression of equatorward meridional flow locally near the base of the convection zone, large-scale equatorward transport of magnetic flux via meridional flow, which is the essential process of the flux-transport dynamo, is sustainable in our calculations.

  11. Effect on lamb meat quality of including thyme (Thymus zygis ssp. gracilis) leaves in ewes' diet.

    Science.gov (United States)

    Nieto, Gema; Díaz, Pedro; Bañón, Sancho; Garrido, María Dolores

    2010-05-01

    The aim of this study was to investigate the effect of including thyme leaves (TL) in the diet of pregnant sheep on the sensorial characteristics, bacterial spoilage and oxidative stability of lamb meat stored in modified atmosphere (70% O(2):30% CO(2)). For this, thirty-six sheep were randomly assigned to three groups: control (basal diet), T(1) (3.7% thyme leaves), T(2) (7.5% thyme leaves). Meat spoilage (TV, PSY, MY, ENT, and LA), TBARS, CIELAB coordinates, metmyoglobin and the sensory characteristics of fresh lamb meat were analyzed on days 0, 7, 14 and 21. The presence of antioxidant compounds in the diet containing TL delayed (Pmeat. In general, this effect was more pronounced at the higher level of TL (7.5%). High Pearson's correlation coefficients were found between the sensory attributes, CIELAB coordinates and TBARS. Copyright (c) 2009 Elsevier Ltd. All rights reserved.

  12. The economic production lot size model extended to include more than one production rate

    DEFF Research Database (Denmark)

    Larsen, Christian

    2005-01-01

    We study an extension of the economic production lot size model, where more than one production rate can be used during a cycle. Moreover, the production rates, as well as their corresponding runtimes are decision variables. We decompose the problem into two subproblems. First, we show that all...

  13. The economic production lot size model extended to include more than one production rate

    DEFF Research Database (Denmark)

    Larsen, Christian

    2001-01-01

    We study an extension of the economic production lot size model, where more than one production rate can be used during a cycle. Moreover, the production rates, as well as their corresponding runtimes are decision variables. First, we show that all production rates should be choosen in the interval...

  14. Description of the new version 4.0 of the tritium model UFOTRI including user guide

    International Nuclear Information System (INIS)

    Raskob, W.

    1993-08-01

    In view of the future operation of fusion reactors the release of tritium may play a dominant role during normal operation as well as after accidents. Because of its physical and chemical properties which differ significantly from those of other radionuclides, the model UFOTRI for assessing the radiological consequences of accidental tritium releases has been developed. It describes the behaviour of tritium in the biosphere and calculates the radiological impact on individuals and the population due to the direct exposure and by the ingestion pathways. Processes such as the conversion of tritium gas into tritiated water (HTO) in the soil, re-emission after deposition and the conversion of HTO into organically bound tritium, are considered. The use of UFOTRI in its probabilistic mode shows the spectrum of the radiological impact together with the associated probability of occurrence. A first model version was established in 1991. As the ongoing work on investigating the main processes of the tritium behaviour in the environment shows up new results, the model has been improved in several points. The report describes the changes incorporated into the model since 1991. Additionally provides the up-dated user guide for handling the revised UFOTRI version which will be distributed to interested organizations. (orig.) [de

  15. Extending the formal model of a spatial data infrastructure to include volunteered geographical information

    CSIR Research Space (South Africa)

    Cooper, Antony K

    2011-07-01

    Full Text Available -to-date VGI, have led to the integration of VGI into some SDIs. Therefore it is necessary to rethink our formal model of an SDI to accommodate VGI. We started our rethinking process with the SDI stakeholders in an attempt to establish which changes...

  16. Loss and thermal model for power semiconductors including device rating information

    DEFF Research Database (Denmark)

    Ma, Ke; Bahman, Amir Sajjad; Beczkowski, Szymon

    2014-01-01

    pre-defined by experience with poor design flexibility. Consequently a more complete loss and thermal model is proposed in this paper, which takes into account not only the electrical loading but also the device rating as input variables. The quantified correlation between the power loss, thermal...

  17. Social Rationality as a Unified Model of Man (Including Bounded Rationality)

    NARCIS (Netherlands)

    Lindenberg, Siegwart

    2001-01-01

    In 1957, Simon published a collection of his essays under the title of “Models of Man: Social and Rational”. In the preface, he explains the choice for this title: All of the essays “are concerned with laying foundations for a science of man that will comfortably accommodate his dual nature as a

  18. Simple vibration modeling of structural fuzzy with continuous boundary by including two-dimensional spatial memory

    DEFF Research Database (Denmark)

    Friis, Lars; Ohlrich, Mogens

    2008-01-01

    is considered as one or more fuzzy substructures that are known in some statistical sense only. Experiments have shown that such fuzzy substructures often introduce a damping in the master which is much higher than the structural losses account for. A special method for modeling fuzzy substructures with a one...

  19. Modeling the elastic behavior of ductile cast iron including anisotropy in the graphite nodules

    DEFF Research Database (Denmark)

    Andriollo, Tito; Thorborg, Jesper; Hattel, Jesper Henri

    2016-01-01

    by means of a 3D periodic unit cell model. In this respect, an explicit procedure to enforce both periodic displacement and periodic traction boundary conditions in ABAQUS is presented, and the importance of fulfilling the traction continuity conditions at the unit cell boundaries is discussed. It is shown...

  20. Adaptive fuzzy neural network control design via a T-S fuzzy model for a robot manipulator including actuator dynamics.

    Science.gov (United States)

    Wai, Rong-Jong; Yang, Zhi-Wei

    2008-10-01

    This paper focuses on the development of adaptive fuzzy neural network control (AFNNC), including indirect and direct frameworks for an n-link robot manipulator, to achieve high-precision position tracking. In general, it is difficult to adopt a model-based design to achieve this control objective due to the uncertainties in practical applications, such as friction forces, external disturbances, and parameter variations. In order to cope with this problem, an indirect AFNNC (IAFNNC) scheme and a direct AFNNC (DAFNNC) strategy are investigated without the requirement of prior system information. In these model-free control topologies, a continuous-time Takagi-Sugeno (T-S) dynamic fuzzy model with online learning ability is constructed to represent the system dynamics of an n-link robot manipulator. In the IAFNNC, an FNN estimator is designed to tune the nonlinear dynamic function vector in fuzzy local models, and then, the estimative vector is used to indirectly develop a stable IAFNNC law. In the DAFNNC, an FNN controller is directly designed to imitate a predetermined model-based stabilizing control law, and then, the stable control performance can be achieved by only using joint position information. All the IAFNNC and DAFNNC laws and the corresponding adaptive tuning algorithms for FNN weights are established in the sense of Lyapunov stability analyses to ensure the stable control performance. Numerical simulations and experimental results of a two-link robot manipulator actuated by dc servomotors are given to verify the effectiveness and robustness of the proposed methodologies. In addition, the superiority of the proposed control schemes is indicated in comparison with proportional-differential control, fuzzy-model-based control, T-S-type FNN control, and robust neural fuzzy network control systems.

  1. A catchment-scale groundwater model including sewer pipe leakage in an urban system

    Science.gov (United States)

    Peche, Aaron; Fuchs, Lothar; Spönemann, Peter; Graf, Thomas; Neuweiler, Insa

    2016-04-01

    Keywords: pipe leakage, urban hydrogeology, catchment scale, OpenGeoSys, HYSTEM-EXTRAN Wastewater leakage from subsurface sewer pipe defects leads to contamination of the surrounding soil and groundwater (Ellis, 2002; Wolf et al., 2004). Leakage rates at pipe defects have to be known in order to quantify contaminant input. Due to inaccessibility of subsurface pipe defects, direct (in-situ) measurements of leakage rates are tedious and associated with a high degree of uncertainty (Wolf, 2006). Proposed catchment-scale models simplify leakage rates by neglecting unsaturated zone flow or by reducing spatial dimensions (Karpf & Krebs, 2013, Boukhemacha et al., 2015). In the present study, we present a physically based 3-dimensional numerical model incorporating flow in the pipe network, in the saturated zone and in the unsaturated zone to quantify leakage rates on the catchment scale. The model consists of the pipe network flow model HYSTEM-EXTAN (itwh, 2002), which is coupled to the subsurface flow model OpenGeoSys (Kolditz et al., 2012). We also present the newly developed coupling scheme between the two flow models. Leakage functions specific to a pipe defect are derived from simulations of pipe leakage using spatially refined grids around pipe defects. In order to minimize computational effort, these leakage functions are built into the presented numerical model using unrefined grids around pipe defects. The resulting coupled model is capable of efficiently simulating spatially distributed pipe leakage coupled with subsurficial water flow in a 3-dimensional environment. References: Boukhemacha, M. A., Gogu, C. R., Serpescu, I., Gaitanaru, D., & Bica, I. (2015). A hydrogeological conceptual approach to study urban groundwater flow in Bucharest city, Romania. Hydrogeology Journal, 23(3), 437-450. doi:10.1007/s10040-014-1220-3. Ellis, J. B., & Revitt, D. M. (2002). Sewer losses and interactions with groundwater quality. Water Science and Technology, 45(3), 195

  2. Including Antenna Models in Microwave Imaging for Breast-Cancer Screening

    DEFF Research Database (Denmark)

    Rubæk, Tonny; Meincke, Peter

    2006-01-01

    Microwave imaging is emerging as a tool for screening for breast cancer, but the lack of methods for including the characteristics of the antennas of the imaging systems in the imaging algorithms limits their performance. In this paper, a method for incorporating the full antenna characteristics...

  3. Effects of Low Light on Agronomic and Physiological Characteristics of Rice Including Grain Yield and Quality

    Directory of Open Access Journals (Sweden)

    Qi-hua LIU

    2014-09-01

    Full Text Available Light intensity is one of the most important environmental factors that determine the basic characteristics of rice development. However, continuously cloudy weather or rainfall, especially during the grain-filling stage, induces a significant loss in yield and results in poor grain quality. Stress caused by low light often creates severe meteorological disasters in some rice-growing regions worldwide. This review was based on our previous research and related research regarding the effects of low light on rice growth, yield and quality as well as the formation of grain, and mainly reviewed the physiological metabolism of rice plants, including characteristics of photosynthesis, activities of antioxidant enzymes in rice leaves and key enzymes involved in starch synthesis in grains, as well as the translocations of carbohydrate and nitrogen. These characteristics include various grain yield and rice quality components (milling and appearance as well as cooking, eating and nutritional qualities under different rates of shading imposed at the vegetative or reproductive stages of rice plants. Furthermore, we discussed why grain yield and quality are reduced under the low light environment. Next, we summarized the need for future research that emphasizes methods can effectively improve rice grain yield and quality under low light stress. These research findings can provide a beneficial reference for rice cultivation management and breeding program in low light environments.

  4. Paint Pavement Marking Performance Prediction Model That Includes the Impacts of Snow Removal Operations

    Science.gov (United States)

    2011-03-01

    Hypothesized that snow plows wear down mountain road pavement markings. 2007 Craig et al. -Edge lines degrade slower than center/skip lines 2007...retroreflectivity to create the models. They discovered that paint pavement markings last 80% longer on Portland Cement Concrete than Asphalt Concrete at low AADT...retroreflectivity, while yellow markings lost 21%. Lu and Barter attributed the sizable degradation to snow removal, sand application, and studded

  5. An earth outgoing longwave radiation climate model. II - Radiation with clouds included

    Science.gov (United States)

    Yang, Shi-Keng; Smith, G. Louis; Bartman, Fred L.

    1988-01-01

    The model of the outgoing longwave radiation (OLWR) of Yang et al. (1987) is modified by accounting for the presence of clouds and their influence on OLWR. Cloud top temperature was adjusted so that the calculation agreed with NOAA scanning radiometer measurements. Cloudy sky cases were calculated for global average, zonal average, and worldwide distributed cases. The results were found to agree well with satellite observations.

  6. Modelling topical photodynamic therapy treatment including the continuous production of Protoporphyrin IX

    Science.gov (United States)

    Campbell, C. L.; Brown, C. T. A.; Wood, K.; Moseley, H.

    2016-11-01

    Most existing theoretical models of photodynamic therapy (PDT) assume a uniform initial distribution of the photosensitive molecule, Protoporphyrin IX (PpIX). This is an adequate assumption when the prodrug is systematically administered; however for topical PDT this is no longer a valid assumption. Topical application and subsequent diffusion of the prodrug results in an inhomogeneous distribution of PpIX, especially after short incubation times, prior to light illumination. In this work a theoretical simulation of PDT where the PpIX distribution depends on the incubation time and the treatment modality is described. Three steps of the PpIX production are considered. The first is the distribution of the topically applied prodrug, the second in the conversion from the prodrug to PpIX and the third is the light distribution which affects the PpIX distribution through photobleaching. The light distribution is modelled using a Monte Carlo radiation transfer model and indicates treatment depths of around 2 mm during daylight PDT and approximately 3 mm during conventional PDT. The results suggest that treatment depths are not only limited by the light penetration but also by the PpIX distribution.

  7. Three-Dimensional Orbits of Earth Satellites, Including Effects of Earth Oblateness and Atmospheric Rotation

    Science.gov (United States)

    Nielsen, Jack N.; Goodwin, Frederick K.; Mersman, William A.

    1958-01-01

    The principal purpose of the present paper is to present sets of equations which may be used for calculating complete trajectories of earth satellites from outer space to the ground under the influence of air drag and gravity, including oblateness effects, and to apply these to several examples of entry trajectories starting from a circular orbit. Equations of motion, based on an "instantaneous ellipse" technique, with polar angle as independent variable, were found suitable for automatic computation of orbits in which the trajectory consists of a number of revolutions. This method is suitable as long as the trajectory does not become nearly vertical. In the terminal phase of the trajectories, which are nearly vertical, equations of motion in spherical polar coordinates with time as the independent variable were found to be more suitable. In the first illustrative example the effects of the oblateness component of the earth's gravitational field and of atmospheric rotation were studied for equatorial orbits. The satellites were launched into circular orbits at a height of 120 miles, an altitude sufficiently high that a number of revolutions could be studied. The importance of the oblateness component of the earth's gravitational field is shown by the fact that a satellite launched at circular orbital speed, neglecting oblateness, has a perigee some 67,000 feet lower when oblateness forces are included in the equations of motion than when they are not included. Also, the loss in altitude per revolution is double that of a satellite following an orbit not subject to oblateness. The effect of atmospheric rotation on the loss of altitude per revolution was small. As might be surmised, the regression of the line of nodes as predicted by celestial mechanics is unchanged when drag is included. It is clear that the inclination of the orbital plane to the equator will be relatively unaffected by drag for no atmospheric rotation since the drag lies in the orbital plane in

  8. Turbulent inflow and wake of a marine hydrokinetic turbine, including effects of wave motion

    Science.gov (United States)

    Dewhurst, Toby; Rowell, Matthew; Decew, Judson; Baldwin, Ken; Swift, Rob; Wosnik, Martin

    2012-11-01

    A research program to investigate the spatio-temporal structure of turbulent flows relevant to marine hydrokinetic (MHK) energy conversion, including turbulent inflow and turbine wakes, has been initiated at UNH. A scale model MHK turbine was deployed from a floating platform at two open water tidal energy test sites, one sheltered (Great Bay Estuary, NH) and one exposed (Muskeget Channel, MA). The inflow upstream of the turbine under test was characterized using an acoustic Doppler Velocimeter (ADV) and an acoustic Doppler current profiler (ADCP), which vary considerably in temporal and spatial resolution as well as practical applicability in this environment. The turbine was operated at previously determined peak efficiency for a given tidal current. The wake of the turbine was measured with a second, traversing ADV during ramp-up and at peak tidal current velocities, at two to six shroud diameters downstream. An inertial motion unit installed near the turbine hub is used to correct for platform motion. A platform-mounted wave-staff and an independently taut-moored pressure sensor were used to measure wave climate. Together, these data are used to validate theoretical and tank model results for utilizing surface-based platforms for MHK turbine deployments.

  9. Hamiltonian and Lagrangian dynamics of charged particles including the effects of radiation damping

    Science.gov (United States)

    Qin, Hong; Burby, Joshua; Davidson, Ronald; Fisch, Nathaniel; Chung, Moses

    2015-11-01

    The effects of radiation damping (radiation reaction) on accelerating charged particles in modern high-intensity accelerators and high-intensity laser beams have becoming increasingly important. Especially for electron accelerators and storage rings, radiation damping is an effective mechanism and technique to achieve high beam luminosity. We develop Hamiltonian and Lagrangian descriptions of the classical dynamics of a charged particle including the effects of radiation damping in the general electromagnetic focusing channels encountered in accelerators. The direct connection between the classical Hamiltonian and Lagrangian theories and the more fundamental QED description of the synchrotron radiation process is also addressed. In addition to their theoretical importance, the classical Hamiltonian and Lagrangian theories of the radiation damping also enable us to numerically integrate the dynamics using advanced structure-preserving geometric algorithms. These theoretical developments can also be applied to runaway electrons and positrons generated during the disruption or startup of tokamak discharges. This research was supported by the U.S. Department of Energy (DE-AC02-09CH11466).

  10. porewater chemistry experiment at Mont Terri rock laboratory. Reactive transport modelling including bacterial activity

    International Nuclear Information System (INIS)

    Tournassat, Christophe; Gaucher, Eric C.; Leupin, Olivier X.; Wersin, Paul

    2010-01-01

    Document available in extended abstract form only. An in-situ test in the Opalinus Clay formation, termed pore water Chemistry (PC) experiment, was run for a period of five years. It was based on the concept of diffusive equilibration whereby traced water with a composition close to that expected in the formation was continuously circulated and monitored in a packed off borehole. The main original focus was to obtain reliable data on the pH/pCO 2 of the pore water, but because of unexpected microbially- induced redox reactions, the objective was then changed to elucidate the biogeochemical processes happening in the borehole and to understand their impact on pH/pCO 2 and pH in the low permeability clay formation. The biologically perturbed chemical evolution of the PC experiment was simulated with reactive transport models. The aim of this modelling exercise was to develop a 'minimal-' model able to reproduce the chemical evolution of the PC experiment, i.e. the chemical evolution of solute inorganic and organic compounds (organic carbon, dissolved inorganic carbon etc...) that are coupled with each other through the simultaneous occurrence of biological transformation of solute or solid compounds, in-diffusion and out-diffusion of solute species and precipitation/dissolution of minerals (in the borehole and in the formation). An accurate description of the initial chemical conditions in the surrounding formation together with simplified kinetics rule mimicking the different phases of bacterial activities allowed reproducing the evolution of all main measured parameters (e.g. pH, TOC). Analyses from the overcoring and these simulations evidence the high buffer capacity of Opalinus clay regarding chemical perturbations due to bacterial activity. This pH buffering capacity is mainly attributed to the carbonate system as well as to the clay surfaces reactivity. Glycerol leaching from the pH-electrode might be the primary organic source responsible for

  11. Able but unintelligent: including positively stereotyped black subgroups in the stereotype content model.

    Science.gov (United States)

    Walzer, Amy S; Czopp, Alexander M

    2011-01-01

    The stereotype content model (SCM) posits that warmth and competence are the key components underlying judgments about social groups. Because competence can encompass different components (e.g., intelligence, talent) different group members may be perceived to be competent for different reasons. Therefore, we believe it may be important to specify the type of competence being assessed when examining perceptions of groups that are positively stereotyped (i.e., Black athletes and musical Blacks). Consistent with the SCM, these subgroups were perceived as high in competence-talent but not in competence-intelligence and low in warmth. Both the intelligence and talent frame of competence fit in the SCM's social structural hypothesis.

  12. Statistical methodology for discrete fracture model - including fracture size, orientation uncertainty together with intensity uncertainty and variability

    International Nuclear Information System (INIS)

    Darcel, C.; Davy, P.; Le Goc, R.; Dreuzy, J.R. de; Bour, O.

    2009-11-01

    the other, addresses the issue of the nature of the transition. We develop a new 'mechanistic' model that could help in modeling why and where this transition can occur. The transition between both regimes would occur for a fracture length of 1-10 m and even at a smaller scale for the few outcrops that follow the self-similar density model. A consequence for the disposal issue is that the model that is likely to apply in the 'blind' scale window between 10-100 m is the self-similar model as it is defined for large-scale lineaments. The self-similar model, as it is measured for some outcrops and most lineament maps, is definitely worth being investigated as a reference for scales above 1-10 m. In the rest of the report, we develop a methodology for incorporating uncertainty and variability into the DFN modeling. Fracturing properties arise from complex processes which produce an intrinsic variability; characterizing this variability as an admissible variation of model parameter or as the division of the site into subdomains with distinct DFN models is a critical point of the modeling effort. Moreover, the DFN model encompasses a part of uncertainty, due to data inherent uncertainties and sampling limits. Both effects must be quantified and incorporated into the DFN site model definition process. In that context, all available borehole data including recording of fracture intercept positions, pole orientation and relative uncertainties are used as the basis for the methodological development and further site model assessment. An elementary dataset contains a set of discrete fracture intercepts from which a parent orientation/density distribution can be computed. The elementary bricks of the site, from which these initial parent density distributions are computed, rely on the former Single Hole Interpretation division of the boreholes into sections whose local boundaries are expected to reflect - locally - geology and fracturing properties main characteristics. From that

  13. Third-order transfer matrices calculated for an electrostatic toroidal sector condenser including fringing-field effects

    CERN Document Server

    Mordik, S N

    2002-01-01

    The third-order transfer matrices are calculated for an electrostatic toroidal sector condenser using a rigorously conserved matrix method that implies the conservation of the beam phase volume at each step in the calculations. The transfer matrices (matrizants) obtained, include the fringing-field effect due to the stray fields. In the case of a rectangular distribution of the field components along the optical axis, the analytical expressions for all aberration coefficients, including the dispersion ones, are derived accurate to the third-order terms. In simulations of real fields with the stray field width other than zero, a smooth distribution of the field components is used for which similar aberration coefficients were calculated by means of the conserved numerical method . It has been found that for a smooth model, as the stray field width tends to zero, the aberration coefficients approach the corresponding aberration values in the rectangular model.

  14. Multiple Crack Growth Prediction in AA2024-T3 Friction Stir Welded Joints, Including Manufacturing Effects

    DEFF Research Database (Denmark)

    Carlone, Pierpaolo; Citarella, Roberto; Sonne, Mads Rostgaard

    2016-01-01

    boundary element method (FEM-DBEM) procedure, coupling the welding process simulation to the subsequent crack growth assessment, is proposed and applied to simulate multiple crack propagation, with allowance for manufacturing effects. The friction stir butt welding process of the precipitation hardened AA......2024-T3 alloy was simulated using a thermo-mechanical FEM model to predict the process induced residual stress field and material softening. The computed stress field was transferred to a DBEM environment and superimposed to the stress field produced by a remote fatigue traction load applied...... on a notched specimen. The whole procedure was finally tested comparing simulation outcomes with experimental data. The good agreement obtained highlights the predictive capability of the method. The influence of the residual stress distribution on crack growth and the mutual interaction between propagating...

  15. Effects of embedment including slip and separation on seismic SSI response of a nuclear reactor building

    International Nuclear Information System (INIS)

    Saxena, Navjeev; Paul, D.K.

    2012-01-01

    Highlights: ► Both the slip and separation of reactor base reduce with increase in embedment. ► The slip and separation become insignificant beyond 1/4 and 1/2 embedment respectively. ► The stresses in reactor reduce significantly upto 1/4 embedment. ► The stress reduction with embedment is more pronounced in case of tensile stresses. ► The modeling of interface is important beyond 1/8 embedment as stresses are underestimated otherwise. - Abstract: The seismic response of nuclear reactor containment building considering the effects of embedment, slip and separation at soil–structure interface requires modeling of the soil, structure and interface altogether. Slip and separation at the interface causes stress redistribution in the soil and the structure around the interface. The embedment changes the dynamic characteristics of the soil–structure system. Consideration of these aspects allows capturing the realistic response of the structure, which has been a research gap and presented here individually as well as taken together. Finite element analysis has been carried out in time domain to attempt the highly nonlinear problem. The study draws important conclusions useful for design of nuclear reactor containment building.

  16. North american natural gas supply forecast: the Hubbert method including the effects of institutions

    International Nuclear Information System (INIS)

    Reynolds, D. B.; Kolodziej, M.

    2009-01-01

    In this article, the U.S. and southern Canadian natural gas supply market is considered. An important model for oil and natural gas supply is the Hubbert curve. Not all regions of the world are producing oil or natural gas following a Hubbert curve, even when price and market conditions are accounted for. One reason is that institutions are affecting supply. We investigate the possible effects of oil and gas market institutions in North America on natural gas supply. A multi-cycle Hubbert curve with inflection points similar to the Soviet Union's oil production multi-cycle Hubbert curve is used to determine North American natural gas discovery rates and to analyze how market specific institutions caused the inflection points. In addition, we analyze the latest shale natural gas projections critically. While currently, unconventional resources of natural gas suggest that North American natural gas production will increase without bound, the model here suggests a peak in North American natural gas supplies could happen in 2013. (author)

  17. North American Natural Gas Supply Forecast: The Hubbert Method Including the Effects of Institutions

    Directory of Open Access Journals (Sweden)

    Marek Kolodziej

    2009-05-01

    Full Text Available In this article, the U.S. and southern Canadian natural gas supply market is considered. An important model for oil and natural gas supply is the Hubbert curve. Not all regions of the world are producing oil or natural gas following a Hubbert curve, even when price and market conditions are accounted for. One reason is that institutions are affecting supply. We investigate the possible effects of oil and gas market institutions in North America on natural gas supply. A multi-cycle Hubbert curve with inflection points similar to the Soviet Union’s oil production multi-cycle Hubbert curve is used to determine North American natural gas discovery rates and to analyze how market specific institutions caused the inflection points. In addition, we analyze the latest shale natural gas projections critically. While currently, unconventional resources of natural gas suggest that North American natural gas production will increase without bound, the model here suggests a peak in North American natural gas supplies could happen in 2013.

  18. Modelled hydraulic redistribution by sunflower (Helianthus annuus L.) matches observed data only after including night-time transpiration.

    Science.gov (United States)

    Neumann, Rebecca B; Cardon, Zoe G; Teshera-Levye, Jennifer; Rockwell, Fulton E; Zwieniecki, Maciej A; Holbrook, N Michele

    2014-04-01

    The movement of water from moist to dry soil layers through the root systems of plants, referred to as hydraulic redistribution (HR), occurs throughout the world and is thought to influence carbon and water budgets and ecosystem functioning. The realized hydrologic, biogeochemical and ecological consequences of HR depend on the amount of redistributed water, whereas the ability to assess these impacts requires models that correctly capture HR magnitude and timing. Using several soil types and two ecotypes of sunflower (Helianthus annuus L.) in split-pot experiments, we examined how well the widely used HR modelling formulation developed by Ryel et al. matched experimental determination of HR across a range of water potential driving gradients. H. annuus carries out extensive night-time transpiration, and although over the last decade it has become more widely recognized that night-time transpiration occurs in multiple species and many ecosystems, the original Ryel et al. formulation does not include the effect of night-time transpiration on HR. We developed and added a representation of night-time transpiration into the formulation, and only then was the model able to capture the dynamics and magnitude of HR we observed as soils dried and night-time stomatal behaviour changed, both influencing HR. © 2013 John Wiley & Sons Ltd.

  19. Including temperature in a wavefunction description of the dynamics of the quantum Rabi model

    Science.gov (United States)

    Werther, Michael; Grossmann, Frank

    2018-01-01

    We present a wavefunction methodology to account for finite temperature initial conditions in the quantum Rabi model. The approach is based on the Davydov Ansatz together with a statistical sampling of the canonical harmonic oscillator initial density matrix. Equations of motion are gained from a variational principle and numerical results are compared to those of the thermal Hamiltonian approach. For a system consisting of a single spin and a single oscillator and for moderate coupling strength, we compare our new results with full quantum ones as well as with other Davydov-type results based on alternative sampling/summation strategies. All of these perform better than the ones based on the thermal Hamiltonian approach. The best agreement is shown by a Boltzmann weighting of individual eigenstate propagations. Extending this to a bath of many oscillators will, however, be very demanding numerically. The use of any one of the investigated stochastic sampling approaches will then be favorable.

  20. Robust and Adaptive OMR System Including Fuzzy Modeling, Fusion of Musical Rules, and Possible Error Detection

    Directory of Open Access Journals (Sweden)

    Bloch Isabelle

    2007-01-01

    Full Text Available This paper describes a system for optical music recognition (OMR in case of monophonic typeset scores. After clarifying the difficulties specific to this domain, we propose appropriate solutions at both image analysis level and high-level interpretation. Thus, a recognition and segmentation method is designed, that allows dealing with common printing defects and numerous symbol interconnections. Then, musical rules are modeled and integrated, in order to make a consistent decision. This high-level interpretation step relies on the fuzzy sets and possibility framework, since it allows dealing with symbol variability, flexibility, and imprecision of music rules, and merging all these heterogeneous pieces of information. Other innovative features are the indication of potential errors and the possibility of applying learning procedures, in order to gain in robustness. Experiments conducted on a large data base show that the proposed method constitutes an interesting contribution to OMR.

  1. Energy-based fatigue model for shape memory alloys including thermomechanical coupling

    Science.gov (United States)

    Zhang, Yahui; Zhu, Jihong; Moumni, Ziad; Van Herpen, Alain; Zhang, Weihong

    2016-03-01

    This paper is aimed at developing a low cycle fatigue criterion for pseudoelastic shape memory alloys to take into account thermomechanical coupling. To this end, fatigue tests are carried out at different loading rates under strain control at room temperature using NiTi wires. Temperature distribution on the specimen is measured using a high speed thermal camera. Specimens are tested to failure and fatigue lifetimes of specimens are measured. Test results show that the fatigue lifetime is greatly influenced by the loading rate: as the strain rate increases, the fatigue lifetime decreases. Furthermore, it is shown that the fatigue cracks initiate when the stored energy inside the material reaches a critical value. An energy-based fatigue criterion is thus proposed as a function of the irreversible hysteresis energy of the stabilized cycle and the loading rate. Fatigue life is calculated using the proposed model. The experimental and computational results compare well.

  2. Areal rainfall estimation using moving cars - computer experiments including hydrological modeling

    Science.gov (United States)

    Rabiei, Ehsan; Haberlandt, Uwe; Sester, Monika; Fitzner, Daniel; Wallner, Markus

    2016-09-01

    The need for high temporal and spatial resolution precipitation data for hydrological analyses has been discussed in several studies. Although rain gauges provide valuable information, a very dense rain gauge network is costly. As a result, several new ideas have emerged to help estimating areal rainfall with higher temporal and spatial resolution. Rabiei et al. (2013) observed that moving cars, called RainCars (RCs), can potentially be a new source of data for measuring rain rate. The optical sensors used in that study are designed for operating the windscreen wipers and showed promising results for rainfall measurement purposes. Their measurement accuracy has been quantified in laboratory experiments. Considering explicitly those errors, the main objective of this study is to investigate the benefit of using RCs for estimating areal rainfall. For that, computer experiments are carried out, where radar rainfall is considered as the reference and the other sources of data, i.e., RCs and rain gauges, are extracted from radar data. Comparing the quality of areal rainfall estimation by RCs with rain gauges and reference data helps to investigate the benefit of the RCs. The value of this additional source of data is not only assessed for areal rainfall estimation performance but also for use in hydrological modeling. Considering measurement errors derived from laboratory experiments, the result shows that the RCs provide useful additional information for areal rainfall estimation as well as for hydrological modeling. Moreover, by testing larger uncertainties for RCs, they observed to be useful up to a certain level for areal rainfall estimation and discharge simulation.

  3. ECO: a generic eutrophication model including comprehensive sediment-water interaction.

    Science.gov (United States)

    Smits, Johannes G C; van Beek, Jan K L

    2013-01-01

    The content and calibration of the comprehensive generic 3D eutrophication model ECO for water and sediment quality is presented. Based on a computational grid for water and sediment, ECO is used as a tool for water quality management to simulate concentrations and mass fluxes of nutrients (N, P, Si), phytoplankton species, detrital organic matter, electron acceptors and related substances. ECO combines integral simulation of water and sediment quality with sediment diagenesis and closed mass balances. Its advanced process formulations for substances in the water column and the bed sediment were developed to allow for a much more dynamic calculation of the sediment-water exchange fluxes of nutrients as resulting from steep concentration gradients across the sediment-water interface than is possible with other eutrophication models. ECO is to more accurately calculate the accumulation of organic matter and nutrients in the sediment, and to allow for more accurate prediction of phytoplankton biomass and water quality in response to mitigative measures such as nutrient load reduction. ECO was calibrated for shallow Lake Veluwe (The Netherlands). Due to restoration measures this lake underwent a transition from hypertrophic conditions to moderately eutrophic conditions, leading to the extensive colonization by submerged macrophytes. ECO reproduces observed water quality well for the transition period of ten years. The values of its process coefficients are in line with ranges derived from literature. ECO's calculation results underline the importance of redox processes and phosphate speciation for the nutrient return fluxes. Among other things, the results suggest that authigenic formation of a stable apatite-like mineral in the sediment can contribute significantly to oligotrophication of a lake after a phosphorus load reduction.

  4. Modeling information technology effectiveness

    OpenAIRE

    Aleksander Lotko

    2005-01-01

    Numerous cases of systems not bringing expected results cause that investments in information technology are treated more and more carefully and are not privileged amongst others. This gives rise to the need for applying costs–effect calculations. Modeling IT effectiveness is a procedure which helps to bring system complexity under control. By using proper measures it is possible to perform an objective investment appraisal for projects under consideration. In the paper, a framework of method...

  5. Numerical analysis of trajectories and aberrations of a Wien filter including the effect of fringing fields

    Science.gov (United States)

    Kato, Makoto; Tsuno, Katsushige

    1990-12-01

    Trajectory equations of a stigmatic Wien filter including the effects of unmatched fringing fields are formulated, and an optimum shape with minimum geometrical aberrations is described. A low-aberration Wien filter is realized under the following conditions: (1) electric and magnetic fields satisfy the orthogonal relation even in the off-axial region, and (2) gap lengths between electrodes and magnetic poles are the same for achieving the balancing condition of electric and magnetic forces in fringing regions. The former condition can be realized by both fields with finite but the same hexapole components; this fact enables us to design a filter with simplified geometry that fulfills the latter condition simultaneously. It is shown that a large deflection of trajectories and resultant aberrations appear if the gap lengths are set to be different.

  6. Triple Active Antiretroviral Regimen Including Enfuvirtide Via the Biojector is Effective and Safe

    Directory of Open Access Journals (Sweden)

    Mona Loutfy

    2007-01-01

    Full Text Available For full HIV virological suppression, three fully active antiretroviral agents are required. New drug classes should be included to ensure that agents are fully active. The addition of enfuvirtide and efavirenz to the present patient’s new antiretroviral regimen ensured that two fully active agents were in use in the setting of a moderate degree of nucleoside resistance and a high level of protease resistance, and where non-nucleoside reverse transcriptase inhibitors were still fully active. Both viral load and CD4 count responded favourably to this regimen. The patient received support from physicians and clinic staff in the introduction and use of enfuvirtide. To reduce injection site reactions, a needle-free injection system (Biojector proved effective.

  7. Effects of Cannabis Use on Human Behavior, Including Cognition, Motivation, and Psychosis: A Review.

    Science.gov (United States)

    Volkow, Nora D; Swanson, James M; Evins, A Eden; DeLisi, Lynn E; Meier, Madeline H; Gonzalez, Raul; Bloomfield, Michael A P; Curran, H Valerie; Baler, Ruben

    2016-03-01

    With a political debate about the potential risks and benefits of cannabis use as a backdrop, the wave of legalization and liberalization initiatives continues to spread. Four states (Colorado, Washington, Oregon, and Alaska) and the District of Columbia have passed laws that legalized cannabis for recreational use by adults, and 23 others plus the District of Columbia now regulate cannabis use for medical purposes. These policy changes could trigger a broad range of unintended consequences, with profound and lasting implications for the health and social systems in our country. Cannabis use is emerging as one among many interacting factors that can affect brain development and mental function. To inform the political discourse with scientific evidence, the literature was reviewed to identify what is known and not known about the effects of cannabis use on human behavior, including cognition, motivation, and psychosis.

  8. Two phase formation of massive elliptical galaxies: study through cross-correlation including spatial effect

    Science.gov (United States)

    Modak, Soumita; Chattopadhyay, Tanuka; Chattopadhyay, Asis Kumar

    2017-11-01

    Area of study is the formation mechanism of the present-day population of elliptical galaxies, in the context of hierarchical cosmological models accompanied by accretion and minor mergers. The present work investigates the formation and evolution of several components of the nearby massive early-type galaxies (ETGs) through cross-correlation function (CCF), using the spatial parameters right ascension (RA) and declination (DEC), and the intrinsic parameters mass (M_{*}) and size. According to the astrophysical terminology, here these variables, namely mass, size, RA and DEC are termed as parameters, whereas the unknown constants involved in the kernel function are called hyperparameters. Throughout this paper, the parameter size is used to represent the effective radius (Re). Following Huang et al. (2013a), each nearby ETG is divided into three parts on the basis of its Re value. We study the CCF between each of these three components of nearby massive ETGs and the ETGs in the high redshift range, 0.5work (De et al. 2014) suggesting other possibilities for the formation of the outermost part. A probable cause of this improvement is the inclusion of the spatial effects in addition to the other parameters in the study.

  9. Stress analysis of fuel claddings with axial fins including creep effects

    International Nuclear Information System (INIS)

    Krieg, R.

    1977-01-01

    For LMFBR fuel claddings with axial fins the stress and strain fields are calculated which may be caused by internal pressure, differential thermal expansion and irradiation induced differential swelling. To provide an appropriate description of the cladding material it is assumed that the total strain is the sum of a linear elastic and a creep term, where the latter one includes the thermal as well as the irradiation induced creep. First the linear elastic problem is treated by a semi-analytical method leading to a bipotential equation for Airys' stress function. Solving this equation analytically means that the field equations valid within the cladding are satisfied exactly. By applying a combined point matching- least square-method the boundary conditions could be satisfied approximately such that in most cases the remaining error is within the uncertainty range of the loading conditions. Then the nonlinear problem which includes creep is approximated by a sequence of linear elastic solutions with time as parameter. The accumulated creep strain is treated here as an imposed strain field. To study the influence of different effects such as fin shape, temperature region, irradiation induced creep and swelling or internal pressure, a total of eleven cases with various parameter variations are investigated. The results are presented graphically in the following forms: stress and strain distributions over the cladding cross section for end of life conditions and boundary stresses and strains versus time. (Auth.)

  10. Thymoquinone causes multiple effects, including cell death, on dividing plant cells.

    Science.gov (United States)

    Hassanien, Sameh E; Ramadan, Ahmed M; Azeiz, Ahmed Z Abdel; Mohammed, Rasha A; Hassan, Sabah M; Shokry, Ahmed M; Atef, Ahmed; Kamal, Khalid B H; Rabah, Samar; Sabir, Jamal S M; Abuzinadah, Osama A; El-Domyati, Fotouh M; Martin, Gregory B; Bahieldin, Ahmed

    2013-01-01

    Thymoquinone (TQ) is a major constituent of Nigella sativa oil with reported anti-oxidative activity and anti-inflammatory activity in animal cells. It also inhibits proliferation and induces programmed cell death (apoptosis) in human skin cancer cells. The present study sought to detect the influence of TQ on dividing cells of three plant systems and on expression of Bcl2-associated athanogene-like (BAG-like) genes that might be involved during the process of cell death. BAG genes are known for the regulation of diverse physiological processes in animals, including apoptosis, tumorigenesis, stress responses, and cell division. Synthetic TQ at 0.1mg/mL greatly reduced wheat seed germination rate, whereas 0.2mg/mL completely inhibited germination. An Evans blue assay revealed moderate cell death in the meristematic zone of Glycine max roots after 1h of TQ treatment (0.2mg/mL), with severe cell death occurring in this zone after 2h of treatment. Light microscopy of TQ-treated (0.2mg/mL) onion hairy root tips for 1h revealed anti-mitotic activity and also cell death-associated changes, including nuclear membrane disruption and nuclear fragmentation. Transmission electron microscopy of TQ-treated cells (0.2mg/mL) for 1h revealed shrinkage of the plasma membrane, leakage of cell lysate, degradation of cell walls, enlargement of vacuoles and condensation of nuclei. Expression of one BAG-like gene, previously associated with cell death, was induced 20 min after TQ treatment in Glycine max root tip cells. Thus, TQ has multiple effects, including cell death, on dividing plant cells and plants may serve as a useful system to further investigate the mechanisms underlying the response of eukaryotic cells to TQ. © 2013. Published by Elsevier SAS.

  11. Enduring effects of severe developmental adversity, including nutritional deprivation, on cortisol metabolism in aging Holocaust survivors.

    Science.gov (United States)

    Yehuda, Rachel; Bierer, Linda M; Andrew, Ruth; Schmeidler, James; Seckl, Jonathan R

    2009-06-01

    In animal models, early life exposure to major environmental challenges such as malnutrition and stress results in persisting cardiometabolic, neuroendocrine and affective effects. While such effects have been associated with pathogenesis, the widespread occurrence of 'developmental programming' suggests it has adaptive function. Glucocorticoids may mediate 'programming' and their metabolism is known to be affected by early life events in rodents. To examine these relationships in humans, cortisol metabolism and cardiometabolic disease manifestations were examined in Holocaust survivors in relation to age at exposure and affective dysfunction, notably lifetime posttraumatic stress disorder (PTSD). Fifty-one Holocaust survivors and 22 controls without Axis I disorder collected 24-h urine samples and were evaluated for psychiatric disorders and cardiometabolic diagnoses. Corticosteroids and their metabolites were assayed by gas chromatography-mass spectroscopy (GC-MS); cortisol was also measured by radioimmunoassay (RIA). Holocaust survivors showed reduced cortisol by RIA, and decreased levels of 5alpha-tetrahydrocortisol (5alpha-THF) and total glucocorticoid production by GC-MS. The latter was associated with lower cortisol metabolism by 5alpha-reductase and 11beta-hydroxysteroid dehydrogenase (11beta-HSD) type-2. The greatest decrements were associated with earliest age of Holocaust exposure and less severe PTSD symptomatology. Cardiometabolic manifestations were associated with decreased 11beta-HSD-2 activity. In controls, 5alpha-reductase was positively associated with trauma-related symptoms (i.e., to traumatic exposures unrelated to the Holocaust). Extreme malnutrition and related stress during development is associated with long-lived alterations in specific pathways of glucocorticoid metabolism. These effects may be adaptive and link with lower risks of cardiometabolic and stress-related disorders in later life.

  12. Improvement in genetic evaluation of female fertility in dairy cattle using multiple-trait models including milk production traits

    DEFF Research Database (Denmark)

    Sun, C; Madsen, P; Lund, M S

    2010-01-01

    This study investigated the improvement in genetic evaluation of fertility traits by using production traits as secondary traits (MILK = 305-d milk yield, FAT = 305-d fat yield, and PROT = 305-d protein yield). Data including 471,742 records from first lactations of Denmark Holstein cows, covering...... (DATAC1, which only contained the first crop daughters) for proven bulls. In addition, the superiority of the models was evaluated by expected reliability of EBV, calculated from the prediction error variance of EBV. Based on these criteria, the models combining milk production traits showed better model...... stability and predictive ability than single-trait models for all the fertility traits, except for nonreturn rate within 56 d after first service. The stability and predictive ability for the model including MILK or PROT were similar to the model including all 3 milk production traits and better than...

  13. PTA-1 computer program for treating pressure transients in hydraulic networks including the effect of pipe plasticity

    International Nuclear Information System (INIS)

    Youngdahl, C.K.; Kot, C.A.

    1977-01-01

    Pressure pulses in the intermediate sodium system of a liquid-metal-cooled fast breeder reactor, such as may originate from a sodium/water reaction in a steam generator, are propagated through the complex sodium piping network to system components such as the pump and intermediate heat exchanger. To assess the effects of such pulses on continued reliable operation of these components and to contribute to system designs which result in the mitigation of these effects, Pressure Transient Analysis (PTA) computer codes are being developed for accurately computing the transmission of pressure pulses through a complicated fluid transport system, consisting of piping, fittings and junctions, and components. PTA-1 provides an extension of the well-accepted and verified fluid hammer formulation for computing hydraulic transients in elastic or rigid piping systems to include plastic deformation effects. The accuracy of the modeling of pipe plasticity effects on transient propagation has been validated using results from two sets of Stanford Research Institute experiments. Validation of PTA-1 using the latter set of experiments is described briefly. The comparisons of PTA-1 computations with experiments show that (1) elastic-plastic deformation of LMFBR-type piping can have a significant qualitative and quantitative effect on pressure pulse propagation, even in simple systems; (2) classical fluid-hammer theory gives erroneous results when applied to situations where piping deforms plastically; and (3) the computational model incorporated in PTA-1 for predicting plastic deformation and its effect on transient propagation is accurate

  14. Landau quantized dynamics and spectra for group-VI dichalcogenides, including a model quantum wire

    Science.gov (United States)

    Horing, Norman J. M.

    2017-06-01

    This work is concerned with the derivation of the Green's function for Landau-quantized carriers in the Group-VI dichalcogenides. In the spatially homogeneous case, the Green's function is separated into a Peierls phase factor and a translationally invariant part which is determined in a closed form integral representation involving only elementary functions. The latter is expanded in an eigenfunction series of Laguerre polynomials. These results for the retarded Green's function are presented in both position and momentum representations, and yet another closed form representation is derived in circular coordinates in terms of the Bessel wave function of the second kind (not to be confused with the Bessel function). The case of a quantum wire is also addressed, representing the quantum wire in terms of a model one-dimensional δ (x ) -potential profile. This retarded Green's function for propagation directly along the wire is determined exactly in terms of the corresponding Green's function for the system without the δ (x ) -potential, and the Landau quantized eigenenergy dispersion relation is examined. The thermodynamic Green's function for the dichalcogenide carriers in a normal magnetic field is formulated here in terms of its spectral weight, and its solution is presented in a momentum/integral representation involving only elementary functions, which is subsequently expanded in Laguerre eigenfunctions and presented in both momentum and position representations.

  15. Landau quantized dynamics and spectra for group-VI dichalcogenides, including a model quantum wire

    Directory of Open Access Journals (Sweden)

    Norman J. M. Horing

    2017-06-01

    Full Text Available This work is concerned with the derivation of the Green’s function for Landau-quantized carriers in the Group-VI dichalcogenides. In the spatially homogeneous case, the Green’s function is separated into a Peierls phase factor and a translationally invariant part which is determined in a closed form integral representation involving only elementary functions. The latter is expanded in an eigenfunction series of Laguerre polynomials. These results for the retarded Green’s function are presented in both position and momentum representations, and yet another closed form representation is derived in circular coordinates in terms of the Bessel wave function of the second kind (not to be confused with the Bessel function. The case of a quantum wire is also addressed, representing the quantum wire in terms of a model one-dimensional δ(x-potential profile. This retarded Green’s function for propagation directly along the wire is determined exactly in terms of the corresponding Green’s function for the system without the δ(x-potential, and the Landau quantized eigenenergy dispersion relation is examined. The thermodynamic Green’s function for the dichalcogenide carriers in a normal magnetic field is formulated here in terms of its spectral weight, and its solution is presented in a momentum/integral representation involving only elementary functions, which is subsequently expanded in Laguerre eigenfunctions and presented in both momentum and position representations.

  16. Statistical methodology for discrete fracture model - including fracture size, orientation uncertainty together with intensity uncertainty and variability

    Energy Technology Data Exchange (ETDEWEB)

    Darcel, C. (Itasca Consultants SAS (France)); Davy, P.; Le Goc, R.; Dreuzy, J.R. de; Bour, O. (Geosciences Rennes, UMR 6118 CNRS, Univ. def Rennes, Rennes (France))

    2009-11-15

    the lineament scale (k{sub t} = 2) on the other, addresses the issue of the nature of the transition. We develop a new 'mechanistic' model that could help in modeling why and where this transition can occur. The transition between both regimes would occur for a fracture length of 1-10 m and even at a smaller scale for the few outcrops that follow the self-similar density model. A consequence for the disposal issue is that the model that is likely to apply in the 'blind' scale window between 10-100 m is the self-similar model as it is defined for large-scale lineaments. The self-similar model, as it is measured for some outcrops and most lineament maps, is definitely worth being investigated as a reference for scales above 1-10 m. In the rest of the report, we develop a methodology for incorporating uncertainty and variability into the DFN modeling. Fracturing properties arise from complex processes which produce an intrinsic variability; characterizing this variability as an admissible variation of model parameter or as the division of the site into subdomains with distinct DFN models is a critical point of the modeling effort. Moreover, the DFN model encompasses a part of uncertainty, due to data inherent uncertainties and sampling limits. Both effects must be quantified and incorporated into the DFN site model definition process. In that context, all available borehole data including recording of fracture intercept positions, pole orientation and relative uncertainties are used as the basis for the methodological development and further site model assessment. An elementary dataset contains a set of discrete fracture intercepts from which a parent orientation/density distribution can be computed. The elementary bricks of the site, from which these initial parent density distributions are computed, rely on the former Single Hole Interpretation division of the boreholes into sections whose local boundaries are expected to reflect - locally - geology

  17. Models for effective prevention.

    Science.gov (United States)

    Perry, C L; Kelder, S H

    1992-07-01

    The social influence models do provide some optimism for primary prevention efforts. Prevention programs appear most effective when 1) the target behavior of the intervention has received increasing societal disapproval (such as cigarette smoking), 2) multiple years of behavioral health education are planned, and 3) community-wide involvement or mass media complement a school-based peer-led program (45,46). Short-term programs and those involving alcohol use have had less favorable outcomes. Future research in primary prevention should address concerns of high-risk groups and high-risk countries, such as lower income populations in the United States or countries that have large adolescent homeless populations. The utilization of adolescent leaders for program dissemination might be particularly critical in these settings. A second major and global concern should focus upon alcohol use and alcohol-related problems. In many communities adolescent alcohol use is normative and even adult supported. Thus, young people are getting quite inconsistent messages on alcohol from their schools, from TV, from peers, and from parents. This inconsistency may translate into many tragic and avoidable deaths for young people. Clearly, in the area of alcohol-related problems, community-wide involvement may be necessary. A third direction for prevention research should involve issues of norms, access, and enforcement including policy interventions, such as involve the availability of cigarette vending machines or the ease of under-age buying or levels of taxation. These methods affect adolescents more acutely since their financial resources, for the most part, are more limited. These policy level methods also signify to adolescents what adults consider appropriate.(ABSTRACT TRUNCATED AT 250 WORDS)

  18. Piping failure analysis for the Korean nuclear piping including the effect of in-service inspection

    Energy Technology Data Exchange (ETDEWEB)

    Choi, S.Y. [Korea Atomic Energy Research Inst.(KAERI), Daejeon (Korea); Choi, Y.H. [Korea Inst. of Nuclear Safety(KINS), Daejeon (Korea)

    2004-07-01

    The purposes of this paper are to perform piping failure analysis for the failed safety class piping in Korean nuclear power plants(NPPs) and evaluate the effect of an in-service inspection(ISI) on the piping failure probability. For data collection, a database for piping failure events was constructed with 135 data fields including population data, event data, and service history data. A total of 6 kinds of events with 25 failure cases up to June 30, 2003 were identified from Korean NPPs. The failed systems were main feedwater system, CVCS, primary sampling system, essential service water system, and CANDU purification system. Piping failure analyses such as evaluation of the impact on nuclear safety and piping integrity and the root cause analysis were performed and the piping failure frequencies for the failed piping were calculated by using population data. The result showed that although the integrity was not maintained in the failed piping, the safety of the plants was maintained for all the events. And the root causes of the events were analyzed as FAC, vibration, thermal fatigue, corrosion, and/or an improper weld joint. The piping failure frequencies ranged from 6.08E-5/Cr-Yr to 1.15E-3/Cr-Yr for the events. According to the ASME Code sec. XI requirements, the small bore piping less than the nominal diameter of 4 inch is exempt from ISI. There, however, were many piping failures reported in the small bore piping. The effect of ISI considering the pipe size on the piping failure probability was investigated by using the Win-PRAISE program based on probabilistic fracture mechanics. The results showed that there is no significant difference between the small and large bore piping from the viewpoint of the ISI effect on the piping failure probability. It means that ISI for a small bore piping is recommended as well as the large bore piping. (orig.)

  19. Cooling Strategies for Vane Leading Edges in a Syngas Environment Including Effects of Deposition and Turbulence

    Energy Technology Data Exchange (ETDEWEB)

    Ames, Forrest [Univ. of North Dakota, Grand Forks, ND (United States); Bons, Jeffrey [Univ. of North Dakota, Grand Forks, ND (United States)

    2014-09-30

    The Department of Energy has goals to move land based gas turbine systems to alternate fuels including coal derived synthetic gas and hydrogen. Coal is the most abundant energy resource in the US and in the world and it is economically advantageous to develop power systems which can use coal. Integrated gasification combined cycles are (IGCC) expected to allow the clean use of coal derived fuels while improving the ability to capture and sequester carbon dioxide. These cycles will need to maintain or increase turbine entry temperatures to develop competitive efficiencies. The use of coal derived syngas introduces a range of potential contaminants into the hot section of the gas turbine including sulfur, iron, calcium, and various alkali metals. Depending on the effectiveness of the gas clean up processes, there exists significant likelihood that the remaining materials will become molten in the combustion process and potentially deposit on downstream turbine surfaces. Past evidence suggests that deposition will be a strong function of increasing temperature. Currently, even with the best gas cleanup processes a small level of particulate matter in the syngas is expected. Consequently, particulate deposition is expected to be an important consideration in the design of turbine components. The leading edge region of first stage vanes most often have higher deposition rates than other areas due to strong fluid acceleration and streamline curvature in the vicinity of the surface. This region remains one of the most difficult areas in a turbine nozzle to cool due to high inlet temperatures and only a small pressure ratio for cooling. The leading edge of a vane often has relatively high heat transfer coefficients and is often cooled using showerhead film cooling arrays. The throat of the first stage nozzle is another area where deposition potentially has a strongly adverse effect on turbine performance as this region meters the turbine inlet flow. Based on roughness

  20. Spectral element modelling of seismic wave propagation in visco-elastoplastic media including excess-pore pressure development

    Science.gov (United States)

    Oral, Elif; Gélis, Céline; Bonilla, Luis Fabián; Delavaud, Elise

    2017-12-01

    Numerical modelling of seismic wave propagation, considering soil nonlinearity, has become a major topic in seismic hazard studies when strong shaking is involved under particular soil conditions. Indeed, when strong ground motion propagates in saturated soils, pore pressure is another important parameter to take into account when successive phases of contractive and dilatant soil behaviour are expected. Here, we model 1-D seismic wave propagation in linear and nonlinear media using the spectral element numerical method. The study uses a three-component (3C) nonlinear rheology and includes pore-pressure excess. The 1-D-3C model is used to study the 1987 Superstition Hills earthquake (ML 6.6), which was recorded at the Wildlife Refuge Liquefaction Array, USA. The data of this event present strong soil nonlinearity involving pore-pressure effects. The ground motion is numerically modelled for different assumptions on soil rheology and input motion (1C versus 3C), using the recorded borehole signals as input motion. The computed acceleration-time histories show low-frequency amplification and strong high-frequency damping due to the development of pore pressure in one of the soil layers. Furthermore, the soil is found to be more nonlinear and more dilatant under triaxial loading compared to the classical 1C analysis, and significant differences in surface displacements are observed between the 1C and 3C approaches. This study contributes to identify and understand the dominant phenomena occurring in superficial layers, depending on local soil properties and input motions, conditions relevant for site-specific studies.

  1. In vitro effectiveness of Castellani solution including various ingredients against different microorganisms

    Directory of Open Access Journals (Sweden)

    Şükran Çopur

    2013-09-01

    Full Text Available Objective: As the external auditory canal is a moisturearea, it facilitates the growth of bacteria and fungi. Infectionsand inflammation due to Staphylococcus aureus,Pseudomonas aeruginosa, Aspergillus spp. and Candidaalbicans can develop in this area. Classical Castellanisolution including boric acid, fenol, fucsin, resorcinol, acetone,and alcohol is used for external ear tract infectionsdue to fungi and bacteria, and also for the superficial dermatophytoses,and eczematous dermatitis of the externalear tract infections.The purpose of this study is to investigate of the in vitroeffectiveness of classical Castellani solution and its differentformulations with different dilutions against the standardyeast and bacteria strains.Methods: C. albicans ATCC 10231, C. krusei ATCC6258, C. dubliniensis CD 36, C. guilliermondii ATCC6260, C. parapsilosis ATCC22019, E. coli ATCC 25922,P. aeruginosa ATCC 27853, MRSA ATCC 43300, Staphylococcusaureus ATCC 25923, and S. epidermidis ATCC12228 strains were included in the study. Broth microdilutionmethod was used for each microorganism and Castellaniformulation. The tests are repeated at least twice.Results: The inhibitory concentration of classical Castellanisolution against bacteria and fungi is 1/64-1/256,1/32-1/64 for fuchsin free solution, 1/32-1/128 for boricacid-free solution and, 1/64-1/128 for resorcinol-free solution.Conclusions: As a conclusion we think that the classicalCastellani solution and its different formulations at variousdilutions may be effective antimicrobial agents for differentpatient populations. J Clin Exp Invest 2013; 4 (3:302-305Key words: Castellani solution, antimicrobial activity, in vitro

  2. Pancreatic Response to Gold Nanoparticles Includes Decrease of Oxidative Stress and Inflammation In Autistic Diabetic Model

    Directory of Open Access Journals (Sweden)

    Manar E. Selim

    2015-01-01

    Full Text Available Background: Gold nanoparticles (AuNPs have a wide range of applications in various fields. This study provides an understanding of the modulatory effects of AuNPs on an antioxidant system in male Wistar diabetic rats with autism spectrum disorder (ASD. Normal littermates fed by control mothers were injected with citrate buffer alone and served as normal, untreated controls controlin this study. Diabetes mellitus (DM was induced by administering a single intraperitoneal injection of streptozotocin (STZ (100 mg/kg to the pups of (ND diabetic group, which had been fasted overnight. Autistic pups from mothers that had received a single intraperitoneal injection of 600 mg/kg sodium valproate on day 12.5 after conception were randomly divided into 2 groups (n 2 7/group as follow; administering single intraperitoneal injection of streptozotocin (STZ ( (100 mg/kg to the overnight fasted autistic pups of (AD autistic diabetic group. The treatment was started on the 5th day after STZ injection with the same dose as in group II and it was considered as 1st day of treatment with gold nanoparticles for 7 days to each rat of (group IV treated autistic diabetic group(TAD at a dosage of 2.5 mg/kg. b. wt. Results: At this dose of administration AuNPs, the activities of hepatic superoxide dismutase (SOD, glutathione peroxidase (GPx, and catalase were greater in group TAD compared with the control group (P 0.05 in the liver of autistic diabetic AuNPs -supplemented rats, whereas reduced glutathione was markedly higher than in control rats, especially after administration of AuNPs. Moreover, the kidney functions in addition to the fat profile scoring supported the protective potential of that dose of AuNPs. The beta cells revealed euchromatic nuclei with no evidence of separation of nuclear membrane. Conclusions: Our results showed that AuNPs improved many of the oxidative stress parameters (SOD, GPx and, CAT, plasma antioxidant capacity (ORAC and lipid profile

  3. Optical potentials derived from microscopic separable interactions including binding and recoil effects

    International Nuclear Information System (INIS)

    Siciliano, E.R.; Walker, G.E.

    1976-01-01

    We first consider a projectile scattering from a nucleon bound in a fixed potential. A separable Galilean invariant projectile-nucleon interaction is adopted. Without using the fixed scatterer approximation or using closure on the intermediate target nucleon states we obtain various forms for the projectile-bound nucleon t matrix. Effects due to intermediate target excitation and nucleon recoil are discussed. By making the further approximations of closure and fixed scatterers we make connection with the work of previous authors. By generalizing to projectile interaction with several bound nucleons and examining the appropriate multiple scattering series we identify the optical potential for projectile elastic scattering from the many-body system. Different optical potentials are obtained for different projectile-bound nucleon t matrices, and we study the differences predicted by these dissimilar optical potentials for elastic scattering. In a model problem, we study pion-nucleus elastic scattering and compare the predictions obtained by adopting procedures used by (1) Landau, Phatak, and Tabakin and (2) Piepho-Walker to the predictions obtained in a less restrictive, but computationally difficult treatment

  4. Theory of energy harvesting from heartbeat including the effects of pleural cavity and respiration

    Science.gov (United States)

    Zhang, Yangyang; Lu, Bingwei; Lü, Chaofeng; Feng, Xue

    2017-11-01

    Self-powered implantable devices with flexible energy harvesters are of significant interest due to their potential to solve the problem of limited battery life and surgical replacement. The flexible electronic devices made of piezoelectric materials have been employed to harvest energy from the motion of biological organs. Experimental measurements show that the output voltage of the device mounted on porcine left ventricle in chest closed environment decreases significantly compared to the case of chest open. A restricted-space deformation model is proposed to predict the impeding effect of pleural cavity, surrounding tissues, as well as respiration on the efficiency of energy harvesting from heartbeat using flexible piezoelectric devices. The analytical solution is verified by comparing theoretical predictions to experimental measurements. A simple scaling law is established to analyse the intrinsic correlations between the normalized output power and the combined system parameters, i.e. the normalized permitted space and normalized electrical load. The results may provide guidelines for optimization of in vivo energy harvesting from heartbeat or the motions of other biological organs using flexible piezoelectric energy harvesters.

  5. Effects of Hot Streak and Phantom Cooling on Heat Transfer in a Cooled Turbine Stage Including Particulate Deposition

    Energy Technology Data Exchange (ETDEWEB)

    Bons, Jeffrey [The Ohio State Univ., Columbus, OH (United States); Ameri, Ali [The Ohio State Univ., Columbus, OH (United States)

    2016-01-08

    The objective of this research effort was to develop a validated computational modeling capability for the characterization of the effects of hot streaks and particulate deposition on the heat load of modern gas turbines. This was accomplished with a multi-faceted approach including analytical, experimental, and computational components. A 1-year no cost extension request was approved for this effort, so the total duration was 4 years. The research effort succeeded in its ultimate objective by leveraging extensive experimental deposition studies complemented by computational modeling. Experiments were conducted with hot streaks, vane cooling, and combinations of hot streaks with vane cooling. These studies contributed to a significant body of corporate knowledge of deposition, in combination with particle rebound and deposition studies funded by other agencies, to provide suitable conditions for the development of a new model. The model includes the following physical phenomena: elastic deformation, plastic deformation, adhesion, and shear removal. It also incorporates material property sensitivity to temperature and tangential-normal velocity rebound cross-dependencies observed in experiments. The model is well-suited for incorporation in CFD simulations of complex gas turbine flows due to its algebraic (explicit) formulation. This report contains model predictions compared to coefficient of restitution data available in the open literature as well as deposition results from two different high temperature turbine deposition facilities. While the model comparisons with experiments are in many cases promising, several key aspects of particle deposition remain elusive. The simple phenomenological nature of the model allows for parametric dependencies to be evaluated in a straightforward manner. This effort also included the first-ever full turbine stage deposition model published in the open literature. The simulations included hot streaks and simulated vane cooling

  6. Quantum three-body reaction dynamics including the geometric phase effect

    International Nuclear Information System (INIS)

    Wu, Y.S.M.

    1992-01-01

    Accurate quantum mechanical reactive scattering calculations within the framework of symmetrized hyperspherical coordinate techniques are presented for several processes involving collisions of an electron with a hydrogen atom and an atom with a diatomic molecule in three-dimensional space, and the collinear collision of an atom with a diatomic molecule. In addition to the interest of the processes themselves, the results are compared with previous experimental and theoretical results in such a way as to provide tests of the general usefulness of the methods used. The general theory for the calculation of accurate differential cross sections in the reactive collision of an atom with a diatomic molecule including the geometric phase effect in three-dimensional space is described. This methodology has permitted, for the first time, the calculation of integral and differential cross sections over a significantly larger range of collision energies (up to 2.6 eV total energy) than previously possible for the system H + H 2 . The authors present numerical solutions of the quantum mechanical streamlines of probability current density for collinear atom-diatom reactions. It is used to study the barrier height dependence of dynamics on the Cl + HCl reaction

  7. Representation-free description of light-pulse atom interferometry including non-inertial effects

    Energy Technology Data Exchange (ETDEWEB)

    Kleinert, Stephan, E-mail: stephan.kleinert@uni-ulm.de [Institut für Quantenphysik and Center for Integrated Quantum Science and Technology (IQST), Universität Ulm, Albert-Einstein-Allee 11, D-89081 Ulm (Germany); Kajari, Endre; Roura, Albert [Institut für Quantenphysik and Center for Integrated Quantum Science and Technology (IQST), Universität Ulm, Albert-Einstein-Allee 11, D-89081 Ulm (Germany); Schleich, Wolfgang P. [Institut für Quantenphysik and Center for Integrated Quantum Science and Technology (IQST), Universität Ulm, Albert-Einstein-Allee 11, D-89081 Ulm (Germany); Texas A& M University Institute for Advanced Study (TIAS), Institute for Quantum Science and Engineering (IQSE) and Department of Physics and Astronomy, Texas A& M University College Station, TX 77843-4242 (United States)

    2015-12-30

    Light-pulse atom interferometers rely on the wave nature of matter and its manipulation with coherent laser pulses. They are used for precise gravimetry and inertial sensing as well as for accurate measurements of fundamental constants. Reaching higher precision requires longer interferometer times which are naturally encountered in microgravity environments such as drop-tower facilities, sounding rockets and dedicated satellite missions aiming at fundamental quantum physics in space. In all those cases, it is necessary to consider arbitrary trajectories and varying orientations of the interferometer set-up in non-inertial frames of reference. Here we provide a versatile representation-free description of atom interferometry entirely based on operator algebra to address this general situation. We show how to analytically determine the phase shift as well as the visibility of interferometers with an arbitrary number of pulses including the effects of local gravitational accelerations, gravity gradients, the rotation of the lasers and non-inertial frames of reference. Our method conveniently unifies previous results and facilitates the investigation of novel interferometer geometries.

  8. Combining prior knowledge with data-driven modeling of a batch distillation column including start-up

    NARCIS (Netherlands)

    van Lith, P.F.; van Lith, Pascal F.; Betlem, Bernardus H.L.; Roffel, B.

    2003-01-01

    This paper presents the development of a simple model which describes the product quality and production over time of an experimental batch distillation column, including start-up. The model structure is based on a simple physical framework, which is augmented with fuzzy logic. This provides a way

  9. Training effectiveness evaluation model

    International Nuclear Information System (INIS)

    Penrose, J.B.

    1993-01-01

    NAESCO's Training Effectiveness Evaluation Model (TEEM) integrates existing evaluation procedures with new procedures. The new procedures are designed to measure training impact on organizational productivity. TEEM seeks to enhance organizational productivity through proactive training focused on operation results. These results can be identified and measured by establishing and tracking performance indicators. Relating training to organizational productivity is not easy. TEEM is a team process. It offers strategies to assess more effectively organizational costs and benefits of training. TEEM is one organization's attempt to refine, manage and extend its training evaluation program

  10. Importance of including small-scale tile drain discharge in the calibration of a coupled groundwater-surface water catchment model

    DEFF Research Database (Denmark)

    Hansen, Anne Lausten; Refsgaard, Jens Christian; Christensen, Britt Stenhøj Baun

    2013-01-01

    the catchment. In this study, a coupled groundwater-surface water model based on the MIKE SHE code was developed for the 4.7 km2 Lillebæk catchment in Denmark, where tile drain flow is a major contributor to the stream discharge. The catchment model was calibrated in several steps by incrementally including...... the observation data into the calibration to see the effect on model performance of including diverse data types, especially tile drain discharge. For the Lillebæk catchment, measurements of hydraulic head, daily stream discharge, and daily tile drain discharge from five small (1–4 ha) drainage areas exist....... The results showed that including tile drain data in the calibration of the catchment model improved its general performance for hydraulic heads and stream discharges. However, the model failed to correctly describe the local-scale dynamics of the tile drain discharges, and, furthermore, including the drain...

  11. Effects of Adiponectin Including Reduction of Androstenedione Secretion and Ovarian Oxidative Stress Parameters In Vivo.

    Directory of Open Access Journals (Sweden)

    Fabio V Comim

    Full Text Available Adiponectin is the most abundantly produced human adipokine with anti-inflammatory, anti-oxidative, and insulin-sensitizing properties. Evidence from in vitro studies has indicated that adiponectin has a potential role in reproduction because it reduces the production of androstenedione in bovine theca cells in vitro. However, this effect on androgen production has not yet been observed in vivo. The current study evaluated the effect of adiponectin on androstenedione secretion and oxidative stress parameters in a rodent model. Seven-week-old female Balb/c mice (n = 33, previously treated with equine gonadotropin chorionic, were assigned to one of four different treatments: Group 1, control (phosphate-buffered saline; Group 2, adiponectin 0.1 μg/mL; Group 3, adiponectin 1.0 μg/mL; Group 4, adiponectin 5.0 μg/mL. After 24 h, all animals were euthanized and androstenedione levels were measured in the serum while oxidative stress markers were quantified in whole ovary tissue. Female mice treated with adiponectin exhibited a significant reduction (about 60% in serum androstenedione levels in comparison to controls. Androstenedione levels decreased from 0.78 ± 0.4 ng/mL (mean ± SD in controls to 0.28 ± 0.06 ng/mL after adiponectin (5 μg/mL treatment (P = 0.01. This change in androgen secretion after 24 hours of treatment was associated with a significant reduction in the expression of CYP11A1 and STAR (but not CYP17A1. In addition, ovarian AOPP product levels, a direct product of protein oxidation, decreased significantly in adiponectin-treated mice (5 μg/mL; AOPP (mean ± SD decreased to 4.3 ± 2.1 μmol/L in comparison with that of the controls (11.5 ± 1.7 μmol/L; P = 0.0003. Our results demonstrated for the first time that acute treatment with adiponectin reduced the levels of a direct oxidative stress marker in the ovary as well as decreased androstenedione serum levels in vivo after 24 h.

  12. Experimental Investigation of Cross-Flow Axis Marine Hydrokinetic Turbines, Including Effects of Waves and Turbulence

    Science.gov (United States)

    Wosnik, M.; Bachant, P.

    2011-12-01

    A new test bed for Marine Hydrokinetic (MHK) turbines at the Center for Ocean Renewable Energy at the University of New Hampshire (UNH-CORE) was used to evaluate the performance of different cross-flow axis hydrokinetic turbines, and investigate the effects of waves and turbulence on these devices. The test bed was designed and built to operate in the UNH tow and wave tank, which has a cross section of 3.67m (width) x 2.44m (depth). In the present configuration, tow speeds of up to 3 m/s can be achieved for smaller turbine models, and up to 1.5 m/s for large turbine models with low gear ratio. It features a flap style wave maker at one end that is capable of producing waves with 1-5 s periods up to 0.4 m wave height. Turbine thrust (drag) and mechanical power output (torque, angular velocity) were measured at tow speeds of 0.6-1.5 m/s for two cross-flow axis MHK turbines: a Gorlov Helical Turbine (GHT) and a Lucid spherical turbine (LST). Both were provided by Lucid Energy Technologies, LLP, and have frontal areas of 1.3 (GHT) and 1.0 (LST) square meters, respectively. GHT performance was also measured in progressive waves of various periods, grid turbulence, and in the wake of a cylinder, installed upstream at various cross-stream locations. Overall, the GHT performs with higher power and thrust (drag) coefficients than the LST. A 2nd law efficiency, or kinetic exergy efficiency, was defined to calculate what fraction of the kinetic energy removed from the flow is converted to usable shaft work by each turbine. The exergy efficiency varies with tip speed ratio but approaches 90% for the optimum operating conditions for each turbine. The fraction of kinetic energy removed from the fluid that is not converted to shaft work is redistributed into turbulent kinetic energy in the wake. Quantifying the kinetic energy flowing out of the turbine is important for modeling of environmental transport processes and for predicting performance when turbines are used in arrays

  13. Ecotoxicological effects extrapolation models

    Energy Technology Data Exchange (ETDEWEB)

    Suter, G.W. II

    1996-09-01

    One of the central problems of ecological risk assessment is modeling the relationship between test endpoints (numerical summaries of the results of toxicity tests) and assessment endpoints (formal expressions of the properties of the environment that are to be protected). For example, one may wish to estimate the reduction in species richness of fishes in a stream reach exposed to an effluent and have only a fathead minnow 96 hr LC50 as an effects metric. The problem is to extrapolate from what is known (the fathead minnow LC50) to what matters to the decision maker, the loss of fish species. Models used for this purpose may be termed Effects Extrapolation Models (EEMs) or Activity-Activity Relationships (AARs), by analogy to Structure-Activity Relationships (SARs). These models have been previously reviewed in Ch. 7 and 9 of and by an OECD workshop. This paper updates those reviews and attempts to further clarify the issues involved in the development and use of EEMs. Although there is some overlap, this paper does not repeat those reviews and the reader is referred to the previous reviews for a more complete historical perspective, and for treatment of additional extrapolation issues.

  14. Modeling, Vicarious Learning, and Basic Needs: Helping All Children (Including Gifted Children) Recover From an Incendiary Political Season

    Science.gov (United States)

    Cross, Tracy L.

    2017-01-01

    This column examines the recent political campaign and possible effects on gifted and talented students. Using psychological theories, the author describes ways that adults can interpret the events and model appropriate American values.

  15. Simulation of Spread of African Swine Fever, Including the Effects of Residues from Dead Animals

    DEFF Research Database (Denmark)

    Hisham Beshara Halasa, Tariq; Boklund, Anette; Bøtner, Anette

    2016-01-01

    the subclinical stage and are fully infectious during the clinical stage. ASF virus (ASFV) infection through residues of dead animals in the slurries was also modeled in an exponentially fading-out pattern. Low and high transmission rates for ASFV were tested in the model. Robustness analysis was carried out......To study the spread of African swine fever (ASF) within a pig unit and the impact of unit size on ASF spread, a simulation model was created. In the model, an animal can be in one of the following stages: susceptible, latent, subclinical, clinical, or recovered. Animals can be infectious during...... in order to study the impact of uncertain parameters on model predictions. The results showed that the disease may fade out within the pig unit without a major outbreak. Furthermore, they showed that spread of ASFV is dependent on the infectiousness of subclinical animals and the residues of dead animals...

  16. Modeling quantization effects in field effect transistors

    CERN Document Server

    Troger, C

    2001-01-01

    Numerical simulation in the field of semiconductor device development advanced to a valuable, cost-effective and flexible facility. The most widely used simulators are based on classical models, as they need to satisfy time and memory constraints. To improve the performance of field effect transistors such as MOSFETs and HEMTs these devices are continuously scaled down in their dimensions. Consequently the characteristics of such devices are getting more and more determined by quantum mechanical effects arising from strong transversal fields in the channel. In this work an approach based on a two-dimensional electron gas is used to describe the confinement of the carriers. Quantization is considered in one direction only. For the derivation of a one-dimensional Schroedinger equation in the effective mass framework a non-parabolic correction for the energy dispersion due to Kane is included. For each subband a non-parabolic dispersion relation characterized by subband masses and subband non-parabolicity coeffi...

  17. The Benefits of Including Clinical Factors in Rectal Normal Tissue Complication Probability Modeling After Radiotherapy for Prostate Cancer

    International Nuclear Information System (INIS)

    Defraene, Gilles; Van den Bergh, Laura; Al-Mamgani, Abrahim; Haustermans, Karin; Heemsbergen, Wilma; Van den Heuvel, Frank; Lebesque, Joos V.

    2012-01-01

    Purpose: To study the impact of clinical predisposing factors on rectal normal tissue complication probability modeling using the updated results of the Dutch prostate dose-escalation trial. Methods and Materials: Toxicity data of 512 patients (conformally treated to 68 Gy [n = 284] and 78 Gy [n = 228]) with complete follow-up at 3 years after radiotherapy were studied. Scored end points were rectal bleeding, high stool frequency, and fecal incontinence. Two traditional dose-based models (Lyman-Kutcher-Burman (LKB) and Relative Seriality (RS) and a logistic model were fitted using a maximum likelihood approach. Furthermore, these model fits were improved by including the most significant clinical factors. The area under the receiver operating characteristic curve (AUC) was used to compare the discriminating ability of all fits. Results: Including clinical factors significantly increased the predictive power of the models for all end points. In the optimal LKB, RS, and logistic models for rectal bleeding and fecal incontinence, the first significant (p = 0.011–0.013) clinical factor was “previous abdominal surgery.” As second significant (p = 0.012–0.016) factor, “cardiac history” was included in all three rectal bleeding fits, whereas including “diabetes” was significant (p = 0.039–0.048) in fecal incontinence modeling but only in the LKB and logistic models. High stool frequency fits only benefitted significantly (p = 0.003–0.006) from the inclusion of the baseline toxicity score. For all models rectal bleeding fits had the highest AUC (0.77) where it was 0.63 and 0.68 for high stool frequency and fecal incontinence, respectively. LKB and logistic model fits resulted in similar values for the volume parameter. The steepness parameter was somewhat higher in the logistic model, also resulting in a slightly lower D 50 . Anal wall DVHs were used for fecal incontinence, whereas anorectal wall dose best described the other two endpoints. Conclusions

  18. Accurate inspiral-merger-ringdown gravitational waveforms for nonspinning black-hole binaries including the effect of subdominant modes

    Science.gov (United States)

    Mehta, Ajit Kumar; Mishra, Chandra Kant; Varma, Vijay; Ajith, Parameswaran

    2017-12-01

    We present an analytical waveform family describing gravitational waves (GWs) from the inspiral, merger, and ringdown of nonspinning black-hole binaries including the effect of several nonquadrupole modes [(ℓ=2 ,m =±1 ),(ℓ=3 ,m =±3 ),(ℓ=4 ,m =±4 ) apart from (ℓ=2 ,m =±2 )]. We first construct spin-weighted spherical harmonics modes of hybrid waveforms by matching numerical-relativity simulations (with mass ratio 1-10) describing the late inspiral, merger, and ringdown of the binary with post-Newtonian/effective-one-body waveforms describing the early inspiral. An analytical waveform family is constructed in frequency domain by modeling the Fourier transform of the hybrid waveforms making use of analytical functions inspired by perturbative calculations. The resulting highly accurate, ready-to-use waveforms are highly faithful (unfaithfulness ≃10-4- 10-2 ) for observation of GWs from nonspinning black-hole binaries and are extremely inexpensive to generate.

  19. A finite element model of the lower limb during stance phase of gait cycle including the muscle forces.

    Science.gov (United States)

    Diffo Kaze, Arnaud; Maas, Stefan; Arnoux, Pierre-Jean; Wolf, Claude; Pape, Dietrich

    2017-12-07

    Results of finite element (FE) analyses can give insight into musculoskeletal diseases if physiological boundary conditions, which include the muscle forces during specific activities of daily life, are considered in the FE modelling. So far, many simplifications of the boundary conditions are currently made. This study presents an approach for FE modelling of the lower limb for which muscle forces were included. The stance phase of normal gait was simulated. Muscle forces were calculated using a musculoskeletal rigid body (RB) model of the human body, and were subsequently applied to a FE model of the lower limb. It was shown that the inertial forces are negligible during the stance phase of normal gait. The contact surfaces between the parts within the knee were modelled as bonded. Weak springs were attached to the distal tibia for numerical reasons. Hip joint reaction forces from the RB model and those from the FE model were similar in magnitude with relative differences less than 16%. The forces of the weak spring were negligible compared to the applied muscle forces. The maximal strain was 0.23% in the proximal region of the femoral diaphysis and 1.7% in the contact zone between the tibia and the fibula. The presented approach based on FE modelling by including muscle forces from inverse dynamic analysis of musculoskeletal RB model can be used to perform analyses of the lower limb with very realistic boundary conditions. In the present form, this model can be used to better understand the loading, stresses and strains of bones in the knee area and hence to analyse osteotomy fixation devices.

  20. Global stability for infectious disease models that include immigration of infected individuals and delay in the incidence

    Directory of Open Access Journals (Sweden)

    Chelsea Uggenti

    2018-03-01

    Full Text Available We begin with a detailed study of a delayed SI model of disease transmission with immigration into both classes. The incidence function allows for a nonlinear dependence on the infected population, including mass action and saturating incidence as special cases. Due to the immigration of infectives, there is no disease-free equilibrium and hence no basic reproduction number. We show there is a unique endemic equilibrium and that this equilibrium is globally asymptotically stable for all parameter values. The results include vector-style delay and latency-style delay. Next, we show that previous global stability results for an SEI model and an SVI model that include immigration of infectives and non-linear incidence but not delay can be extended to systems with vector-style delay and latency-style delay.

  1. A practical kinetic model that considers endproduct inhibition in anaerobic digestion processes by including the equilibrium constant.

    Science.gov (United States)

    Hoh, C Y; Cord-Ruwisch, R

    1996-09-05

    The classical Michaelis-Menten model is widely used as the basis for modeling of a number of biological systems. As the model does not consider the inhibitory effect of endproducts that accumulate in virtually all bioprocesses, it is often modified to prevent the overestimation of reaction rates when products have accumulated. Traditional approaches of model modification use the inclusion of irreversible, competitive, and noncompetitive inhibition factors. This article demonstrates that these inhibition factors are insufficient to predict product inhibition of reactions that are close the dynamic equilibrium. All models investigated were found to violate thermodynamic laws as they predicted positive reaction rates for reactions that were endergonic due to high endproduct concentrations. For modeling of biological processes that operate close to the dynamic equilibrium (e.g., anaerobic processes), it is critical to prevent the prediction of positive reaction rates when the reaction has already reached the dynamic equilibrium. This can be achieved by using a reversible kinetic model. However, the major drawback of the reversible kinetic model is the large number of empirical parameters it requires. These parameters are difficult to determine and prone to experimental error. For this reason, the reversible model is not practical in the modeling of biological processes.This article uses the fundamentals of steady-state kinetics and thermodynamics to establish an equation for the reversible kinetic model that is of practical use in bio-process modeling. The behavior of this equilibrium-based model is compared with Michaelis-Menten-based models that use traditional inhibition factors. The equilibrium-based model did not require any empirical inhibition factor to correctly predict when reaction rates must be zero due to the free energy change being zero. For highly exergonic reactions, the equilibrium-based model did not deviate significantly from the Michaelis

  2. Including load sequence effects in the fatigue damage estimation of an offshore wind turbine substructure

    NARCIS (Netherlands)

    Dragt, R.C.; Maljaars, J.; Tuitman, J.T.; Salman, Y.; Otheguy, M.E.

    2016-01-01

    Retardation is a load sequence effect, which causes a reduced fatigue crack growth rate after an overload is encountered. Retardation can be cancelled when the overload is followed by an underload. The net effect is beneficial to the fatigue lifetime of Offshore Wind Turbines (OWTs). To be able to

  3. A novel method of including Landau level mixing in numerical studies of the quantum Hall effect

    International Nuclear Information System (INIS)

    Wooten, Rachel; Quinn, John; Macek, Joseph

    2013-01-01

    Landau level mixing should influence the quantum Hall effect for all except the strongest applied magnetic fields. We propose a simple method for examining the effects of Landau level mixing by incorporating multiple Landau levels into the Haldane pseudopotentials through exact numerical diagonalization. Some of the resulting pseudopotentials for the lowest and first excited Landau levels will be presented

  4. Including cetaceans in multi-species assessment models using strandings data: why, how and what can we do about it?

    Directory of Open Access Journals (Sweden)

    Camilo Saavedra

    2014-07-01

    Full Text Available Single-species models have been commonly used to assess fish stocks in the past. Since these models have relatively simple data requirements, they sometimes provide the only tool available to assess the status of a stock when data are not enough to develop more complex models. However, these models have been criticized for several reasons since they provide reference points independently for each species assessed ignoring their interactions. For example, several studies suggest that even more substantial reductions in fishing mortality may be necessary to ensure MSY is reached when taking into consideration multiespecies interactions. Therefore, and as Pauly et al. (1998 stated, single-species analysis may mislead researchers and managers into neglecting the gear and trophic interactions which ultimately determine stocks long-term yields and ecosystem health. Ecosystem or multispecies models offer a number of advantages over single-species models. As stated in the workshop “Incorporating ecosystem considerations into stock assessments and management advice” (Mace, 2000 two general improvements are: a better appreciation of the fishing on ecosystem structure and function, and a better appreciation of the need to consider de value of marine ecosystems for functions other than harvesting fish. As disadvantages, multispecies models are statistically complex and include trophic relationships requiring more information (e.g. good estimations of biological parameters of each species and generally a full quantification of the diet sometimes available though the analysis of stomach contents. To reduce the number of species and therefore the amount of information needed, Minimum Realistic Models (MRMs represent an intermediate level of complexity, where only the subset of the ecosystem, important for the issue under consideration, is modeled. This approach offers the advantage of allowing a refinement of our estimates and can help answer more targeted

  5. A new simulation model estimates micronutrient levels to include in fortified blended foods used in food aid programs.

    Science.gov (United States)

    Fleige, Lisa E; Sahyoun, Nadine R; Murphy, Suzanne P

    2010-02-01

    Current micronutrient levels in Public Law 480 fortified blended foods (FBF) may not be appropriate for all food aid beneficiaries, particularly infants and/or young children and pregnant and/or lactating women. A simulation model was developed to determine the micronutrient fortification levels to include in FBF for food aid programs with the goal of reducing the risk of inadequate micronutrient intakes without exceeding the tolerable upper intake level (UL) for any recipient group. For each micronutrient, the age and gender group with the highest daily Recommended Nutrient Intake (RNI) relative to energy requirement was identified and the effect of providing different percentages of that RNI (66, 75, and 100%) was simulated. In this modeling exercise, we also examined consumption of the FBF at 25 (the usual level), 50, and 100% of daily energy requirement. Results indicated that 2 FBF products are needed: a complementary food for age 6-36 mo and a supplementary food for the older groups. Both of the FBF could be fortified to supply at least 75% of the RNI to all groups, without exceeding the UL for most nutrients, if consumed at 25% of the energy requirement. Even if consumed at 50% of energy requirements, mean intakes of most micronutrients would not exceed the UL, although at 100% of the energy requirement, several micronutrients were undesirably high. We conclude that fortifying an FBF to provide 75% of the RNI would be appropriate for most micronutrients, but this level of fortification would not be appropriate for long-term consumption of the FBF at 100% of the energy requirements.

  6. Routing strategy including time and carbon dioxide emissions : effects on network performance

    NARCIS (Netherlands)

    Zhang, Fan; Chen, Y.; Goni Ros, B.; GAO, Jian; Knoop, V.L.

    2016-01-01

    Traffic congestion leads to delays and increased carbon dioxide (CO2) emissions. Traffic management measures such as providing information on environmental route costs have been proposed to mitigate congestion. Multi-criteria routing dynamic traffic assignment (MCR-DTA) models are needed to evaluate

  7. Regular smokeless tobacco use is not a reliable predictor of smoking onset when psychosocial predictors are included in the model.

    Science.gov (United States)

    O'Connor, Richard J; Flaherty, Brian P; Quinio Edwards, Beth; Kozlowski, Lynn T

    2003-08-01

    Tomar analyzed the CDC's Teenage Attitudes and Practices Survey (TAPS) and reported smokeless tobacco may act as a starter product for or gateway to cigarettes. Regular smokeless tobacco users at baseline were said to be 3.45 times more likely than never users of smokeless tobacco to become cigarette smokers after 4 years (95% CI=1.84-6.47). However, this analysis did not take into account well-known psychosocial predictors of smoking initiation. We reanalyzed TAPS to assess whether including psychosocial predictors of smoking affected the smokeless tobacco gateway effect. Experimenting with smoking, OR=2.09 (95% CI=1.51-2.90); below average school performance, OR=9.32 (95% CI=4.18-20.77); household members smoking, OR=1.49 (95% CI=1.13-1.95); frequent depressive symptoms, OR=2.19 (95% CI=1.25-3.84); fighting, OR=1.48 (95% CI=1.08-2.03); and motorcycle riding, OR=1.42 (95% CI=1.06-1.91) diminished the effect of both regular, OR=1.68 (95% CI=.83-3.41), and never regular smokeless tobacco use, OR=1.41 (95% CI=.96-2.05), to be statistically unreliable. Analyzing results from a sample of true never smokers (never a single puff) showed a similar pattern of results. Our results indicate that complex multivariate models are needed to evaluate recruitment to smoking and single factors that are important in that process. Tomar's analysis should not be used as reliable evidence that smokeless tobacco may be a starter product for cigarettes.

  8. Model Selection and Evaluation Based on Emerging Infectious Disease Data Sets including A/H1N1 and Ebola

    Directory of Open Access Journals (Sweden)

    Wendi Liu

    2015-01-01

    Full Text Available The aim of the present study is to apply simple ODE models in the area of modeling the spread of emerging infectious diseases and show the importance of model selection in estimating parameters, the basic reproduction number, turning point, and final size. To quantify the plausibility of each model, given the data and the set of four models including Logistic, Gompertz, Rosenzweg, and Richards models, the Bayes factors are calculated and the precise estimates of the best fitted model parameters and key epidemic characteristics have been obtained. In particular, for Ebola the basic reproduction numbers are 1.3522 (95% CI (1.3506, 1.3537, 1.2101 (95% CI (1.2084, 1.2119, 3.0234 (95% CI (2.6063, 3.4881, and 1.9018 (95% CI (1.8565, 1.9478, the turning points are November 7,November 17, October 2, and November 3, 2014, and the final sizes until December 2015 are 25794 (95% CI (25630, 25958, 3916 (95% CI (3865, 3967, 9886 (95% CI (9740, 10031, and 12633 (95% CI (12515, 12750 for West Africa, Guinea, Liberia, and Sierra Leone, respectively. The main results confirm that model selection is crucial in evaluating and predicting the important quantities describing the emerging infectious diseases, and arbitrarily picking a model without any consideration of alternatives is problematic.

  9. Deliverable 4.2: Methodology for including specific biological effects and pathogen aspects into LCA

    DEFF Research Database (Denmark)

    Larsen, Henrik Fred; Olsen, Stig Irving; Hauschild, Michael Zwicky

    2009-01-01

    .e. endocrine disruptors) and the possibilities and relevance of including impact categories on land use and site-specific assessments have been addressed. Further, the special problems on how to deal with land fill and how to do normalization and weighting of impact potentials are also dealt with. The problem...

  10. Sedimentation-diffusion equilibrium of binary mixtures of charged colloids including volume effects

    NARCIS (Netherlands)

    Biesheuvel, P.M.; Lyklema, J.

    2005-01-01

    We describe the sedimentation-diffusion equilibrium of binary mixtures of charged colloids in the presence of small ions and for non-dilute conditions, by extending the work of Biben and Hansen (1994 J. Phys.: Condens. Matter 6 A345). For a monocomponent system, they included a Carnahan-Starling

  11. Pfirsch-Tasso versus standard approaches in the plasma stability theory including the resistive wall effects

    Science.gov (United States)

    Pustovitov, V. D.

    2017-11-01

    The study is devoted to theoretical description of plasma stability in toroidal fusion systems with a resistive wall. Its aim is elimination of contradictions between the models recently developed for the resistive wall mode analysis and the Pfirsch-Tasso approach originated from the paper published in 1971 [D. Pfirsch and H. Tasso, Nucl. Fusion 11, 259 (1971)]. The main relations have been given there without detailed proofs. Here, a missing chain of derivations is restored and earlier unknown limitations that restrict the applicability of the Pfirsch-Tasso energy principle are established. Its replacement valid in a wider area is proposed. The new result is free from the constraints implicitly imposed in the Pfirsch-Tasso procedure and can be used with any plasma model (not necessarily ideal) and for arbitrary perturbations. The proposed extensions allow applications for analysis of the rotational stabilization and optimization of the ITER scenarios.

  12. Mathematical multi-scale model of the cardiovascular system including mitral valve dynamics. Application to ischemic mitral insufficiency

    Science.gov (United States)

    2011-01-01

    Background Valve dysfunction is a common cardiovascular pathology. Despite significant clinical research, there is little formal study of how valve dysfunction affects overall circulatory dynamics. Validated models would offer the ability to better understand these dynamics and thus optimize diagnosis, as well as surgical and other interventions. Methods A cardiovascular and circulatory system (CVS) model has already been validated in silico, and in several animal model studies. It accounts for valve dynamics using Heaviside functions to simulate a physiologically accurate "open on pressure, close on flow" law. However, it does not consider real-time valve opening dynamics and therefore does not fully capture valve dysfunction, particularly where the dysfunction involves partial closure. This research describes an updated version of this previous closed-loop CVS model that includes the progressive opening of the mitral valve, and is defined over the full cardiac cycle. Results Simulations of the cardiovascular system with healthy mitral valve are performed, and, the global hemodynamic behaviour is studied compared with previously validated results. The error between resulting pressure-volume (PV) loops of already validated CVS model and the new CVS model that includes the progressive opening of the mitral valve is assessed and remains within typical measurement error and variability. Simulations of ischemic mitral insufficiency are also performed. Pressure-Volume loops, transmitral flow evolution and mitral valve aperture area evolution follow reported measurements in shape, amplitude and trends. Conclusions The resulting cardiovascular system model including mitral valve dynamics provides a foundation for clinical validation and the study of valvular dysfunction in vivo. The overall models and results could readily be generalised to other cardiac valves. PMID:21942971

  13. Mathematical multi-scale model of the cardiovascular system including mitral valve dynamics. Application to ischemic mitral insufficiency

    Directory of Open Access Journals (Sweden)

    Moonen Marie

    2011-09-01

    Full Text Available Abstract Background Valve dysfunction is a common cardiovascular pathology. Despite significant clinical research, there is little formal study of how valve dysfunction affects overall circulatory dynamics. Validated models would offer the ability to better understand these dynamics and thus optimize diagnosis, as well as surgical and other interventions. Methods A cardiovascular and circulatory system (CVS model has already been validated in silico, and in several animal model studies. It accounts for valve dynamics using Heaviside functions to simulate a physiologically accurate "open on pressure, close on flow" law. However, it does not consider real-time valve opening dynamics and therefore does not fully capture valve dysfunction, particularly where the dysfunction involves partial closure. This research describes an updated version of this previous closed-loop CVS model that includes the progressive opening of the mitral valve, and is defined over the full cardiac cycle. Results Simulations of the cardiovascular system with healthy mitral valve are performed, and, the global hemodynamic behaviour is studied compared with previously validated results. The error between resulting pressure-volume (PV loops of already validated CVS model and the new CVS model that includes the progressive opening of the mitral valve is assessed and remains within typical measurement error and variability. Simulations of ischemic mitral insufficiency are also performed. Pressure-Volume loops, transmitral flow evolution and mitral valve aperture area evolution follow reported measurements in shape, amplitude and trends. Conclusions The resulting cardiovascular system model including mitral valve dynamics provides a foundation for clinical validation and the study of valvular dysfunction in vivo. The overall models and results could readily be generalised to other cardiac valves.

  14. Effect of including damage at the tissue level in the nonlinear homogenisation of trabecular bone.

    Science.gov (United States)

    Levrero-Florencio, Francesc; Manda, Krishnagoud; Margetts, Lee; Pankaj, Pankaj

    2017-10-01

    Being able to predict bone fracture or implant stability needs a proper constitutive model of trabecular bone at the macroscale in multiaxial, non-monotonic loading modes. Its macroscopic damage behaviour has been investigated experimentally in the past, mostly with the restriction of uniaxial cyclic loading experiments for different samples, which does not allow for the investigation of several load cases in the same sample as damage in one direction may affect the behaviour in other directions. Homogenised finite element models of whole bones have the potential to assess complicated scenarios and thus improve clinical predictions. The aim of this study is to use a homogenisation-based multiscale procedure to upscale the damage behaviour of bone from an assumed solid phase constitutive law and investigate its multiaxial behaviour for the first time. Twelve cubic specimens were each submitted to nine proportional strain histories by using a parallel code developed in-house. Evolution of post-elastic properties for trabecular bone was assessed for a small range of macroscopic plastic strains in these nine load cases. Damage evolution was found to be non-isotropic, and both damage and hardening were found to depend on the loading mode (tensile, compression or shear); both were characterised by linear laws with relatively high coefficients of determination. It is expected that the knowledge of the macroscopic behaviour of trabecular bone gained in this study will help in creating more precise continuum FE models of whole bones that improve clinical predictions.

  15. NASTRAN thermal analyzer: Theory and application including a guide to modeling engineering problems, volume 2. [sample problem library guide

    Science.gov (United States)

    Jackson, C. E., Jr.

    1977-01-01

    A sample problem library containing 20 problems covering most facets of Nastran Thermal Analyzer modeling is presented. Areas discussed include radiative interchange, arbitrary nonlinear loads, transient temperature and steady-state structural plots, temperature-dependent conductivities, simulated multi-layer insulation, and constraint techniques. The use of the major control options and important DMAP alters is demonstrated.

  16. Quantum Effect in a Diode Included Nonlinear Inductance-Capacitance Mesoscopic Circuit

    International Nuclear Information System (INIS)

    Yan Zhanyuan; Zhang Xiaohong; Ma Jinying

    2009-01-01

    The mesoscopic nonlinear inductance-capacitance circuit is a typical anharmonic oscillator, due to diodes included in the circuit. In this paper, using the advanced quantum theory of mesoscopic circuits, which based on the fundamental fact that the electric charge takes discrete value, the diode included mesoscopic circuit is firstly studied. Schroedinger equation of the system is a four-order difference equation in p-circumflex representation. Using the extended perturbative method, the detail energy spectrum and wave functions are obtained and verified, as an application of the results, the current quantum fluctuation in the ground state is calculated. Diode is a basis component in a circuit, its quantization would popularize the quantum theory of mesoscopic circuits. The methods to solve the high order difference equation are helpful to the application of mesoscopic quantum theory.

  17. Quantified, Interactive Simulation of AMCW ToF Camera Including Multipath Effects.

    Science.gov (United States)

    Bulczak, David; Lambers, Martin; Kolb, Andreas

    2017-12-22

    In the last decade, Time-of-Flight (ToF) range cameras have gained increasing popularity in robotics, automotive industry, and home entertainment. Despite technological developments, ToF cameras still suffer from error sources such as multipath interference or motion artifacts. Thus, simulation of ToF cameras, including these artifacts, is important to improve camera and algorithm development. This paper presents a physically-based, interactive simulation technique for amplitude modulated continuous wave (AMCW) ToF cameras, which, among other error sources, includes single bounce indirect multipath interference based on an enhanced image-space approach. The simulation accounts for physical units down to the charge level accumulated in sensor pixels. Furthermore, we present the first quantified comparison for ToF camera simulators. We present bidirectional reference distribution function (BRDF) measurements for selected, purchasable materials in the near-infrared (NIR) range, craft real and synthetic scenes out of these materials and quantitatively compare the range sensor data.

  18. Electron density in reasonably real metallic surfaces, including interchange and correlation effects

    International Nuclear Information System (INIS)

    Moraga, L.A.; Martinez, G.

    1981-01-01

    By means of a new method, the electron density in a jellium surface is calculated taking in account interchange and correlation effects; reproducing, in this way, the Lang and Kohn results. The new method is self-consistent but not iterative and hence is possible extend it to the solution of the same problem in more reasonably real metallic surfaces. (L.C.) [pt

  19. The cost-effectiveness of gestational diabetes screening including prevention of type 2 diabetes

    DEFF Research Database (Denmark)

    Marseille, Elliot; Lohse, Nicolai; Jiwani, Aliya

    2013-01-01

    Gestational diabetes mellitus (GDM) is associated with elevated risks of perinatal complications and type 2 diabetes mellitus, and screening and intervention can reduce these risks. We quantified the cost, health impact and cost-effectiveness of GDM screening and intervention in India and Israel,...

  20. Proceedings of the second US-USSR symposium: air pollution effects on vegetation including forest ecosystems

    Science.gov (United States)

    Reginald D. Noble; Juri L Martin; Keith F., eds. Jensen; Keith F. Jensen

    1989-01-01

    To commemorate the 10th year of cooperation between the US-USSR in the field of environmental protection, a symposium was organized, the major objectives of which were to acquaint US-USSR scientists with project accomplishments; to promote understanding of the nature of environmental problems that relate to air pollution effect on vegetation on a more global scale; to...

  1. Electromagnetic field nonuniformities in large area, high-frequency capacitive plasma reactors, including electrode asymmetry effects

    International Nuclear Information System (INIS)

    Sansonnens, L; Howling, A A; Hollenstein, Ch

    2006-01-01

    Electromagnetic wave propagation effects can give rise to important limitations for processing uniformity in large area, radio-frequency (rf) capacitive plasma reactors. The electromagnetic wavefield solution is derived for a capacitive, high-frequency, cylindrical reactor with symmetric or asymmetric electrode areas containing a uniform plasma slab. It is shown that only two distinct electromagnetic modes are necessary and sufficient to determine the electromagnetic fields everywhere within the reactor except close to the sidewalls. The first mode gives rise to the interelectrode rf voltage standing wave effect associated with high frequencies in large area reactors, and the second mode gives rise to the telegraph effect associated with asymmetric electrode areas, which necessitates the redistribution of rf current along the plasma to maintain rf current continuity. This work gives a unified treatment of both effects which have previously been studied separately, experimentally and theoretically, in the literature. The equivalent circuit of each mode is also derived from its respective dispersion relation. Examples of this electromagnetic wavefield solution show that both modes can cause nonuniformity of the plasma rf potential, depending on the reactor geometry, excitation frequency and plasma permittivity and sheath width, which has consequences for large-area plasma processing

  2. Psychophysiological effects of an iTBS modulated virtual reality challenge including participants with spider phobia.

    Science.gov (United States)

    Notzon, S; Deppermann, S; Fallgatter, A; Diemer, J; Kroczek, A; Domschke, K; Zwanzger, P; Ehlis, A-C

    2015-12-01

    Preliminary evidence suggests beneficial effects of transcranial magnetic stimulation (TMS) on anxiety. The objective of this study was to investigate the effects of intermittent theta burst stimulation (iTBS) as a form of TMS on acute anxiety provoked by a virtual reality (VR) scenario. Participants with spider phobia (n=41) and healthy controls (n=42) were exposed to a spider scenario in VR after one session of iTBS over the prefrontal cortex or sham treatment. Participants with spider phobia reacted with more anxiety compared to healthy controls. Their heart rate and skin conductance increased compared to baseline. Contrary to expectations, iTBS did not influence these reactions, but modulated heart rate variability (HRV). Sympathetic influence on HRV showed an increase in the active iTBS group only. This study does not support the idea of beneficial effects of a single session of iTBS on anxiety, although other protocols or repeated sessions might be effective. Copyright © 2015 Elsevier B.V. All rights reserved.

  3. A review of cell-scale multiphase flow modeling, including water management, in polymer electrolyte fuel cells

    International Nuclear Information System (INIS)

    Andersson, M.; Beale, S.B.; Espinoza, M.; Wu, Z.; Lehnert, W.

    2016-01-01

    on the transport processes inside the porous GDL are extensively discussed. The selection of a computational approach, for the two-phase flow within a GDL or GC, for example, should be based on the computational resources available, concerns about time and scale (microscale, cell scale, stack scale or system scale), as well as accuracy requirements. One important feature, included in some computational approaches, is the possibility to track the front between the liquid and the gas phases. To build a PEFC model, one must make a large number of assumptions. Some assumptions have a negligible effect on the results and reliability of the model. However, other assumptions may significantly affect the result. It is strongly recommended in any modeling paper to clearly state the assumptions being implemented, for others to be able to judge the work. It is important to note that a large fraction of the expressions that presently are used to describe the transport processes inside PEFC GDLs were originally developed to describe significantly different systems, such as sand or rocks. Moreover, the flow pattern maps and pressure drop correlations of two phase flow in micro channels may not be applicable for GCs due to one side wall being porous, with the resulting interaction between the GDL and GC.

  4. Including sheath effects in the interpretation of planar retarding potential analyzer's low-energy ion data.

    Science.gov (United States)

    Fisher, L E; Lynch, K A; Fernandes, P A; Bekkeng, T A; Moen, J; Zettergren, M; Miceli, R J; Powell, S; Lessard, M R; Horak, P

    2016-04-01

    The interpretation of planar retarding potential analyzers (RPA) during ionospheric sounding rocket missions requires modeling the thick 3D plasma sheath. This paper overviews the theory of RPAs with an emphasis placed on the impact of the sheath on current-voltage (I-V) curves. It then describes the Petite Ion Probe (PIP) which has been designed to function in this difficult regime. The data analysis procedure for this instrument is discussed in detail. Data analysis begins by modeling the sheath with the Spacecraft Plasma Interaction System (SPIS), a particle-in-cell code. Test particles are traced through the sheath and detector to determine the detector's response. A training set is constructed from these simulated curves for a support vector regression analysis which relates the properties of the I-V curve to the properties of the plasma. The first in situ use of the PIPs occurred during the MICA sounding rocket mission which launched from Poker Flat, Alaska in February of 2012. These data are presented as a case study, providing valuable cross-instrument comparisons. A heritage top-hat thermal ion electrostatic analyzer, called the HT, and a multi-needle Langmuir probe have been used to validate both the PIPs and the data analysis method. Compared to the HT, the PIP ion temperature measurements agree with a root-mean-square error of 0.023 eV. These two instruments agree on the parallel-to-B plasma flow velocity with a root-mean-square error of 130 m/s. The PIP with its field of view aligned perpendicular-to-B provided a density measurement with an 11% error compared to the multi-needle Langmuir Probe. Higher error in the other PIP's density measurement is likely due to simplifications in the SPIS model geometry.

  5. Adult vaccination strategies for the control of pertussis in the United States: an economic evaluation including the dynamic population effects.

    Directory of Open Access Journals (Sweden)

    Laurent Coudeville

    Full Text Available BACKGROUND: Prior economic evaluations of adult and adolescent vaccination strategies against pertussis have reached disparate conclusions. Using static approaches only, previous studies failed to analytically include the indirect benefits derived from herd immunity as well as the impact of vaccination on the evolution of disease incidence over time. METHODS: We assessed the impact of different pertussis vaccination strategies using a dynamic compartmental model able to consider pertussis transmission. We then combined the results with economic data to estimate the relative cost-effectiveness of pertussis immunization strategies for adolescents and adults in the US. The analysis compares combinations of programs targeting adolescents, parents of newborns (i.e. cocoon strategy, or adults of various ages. RESULTS: In the absence of adolescent or adult vaccination, pertussis incidence among adults is predicted to more than double in 20 years. Implementing an adult program in addition to childhood and adolescent vaccination either based on 1 a cocoon strategy and a single booster dose or 2 a decennial routine vaccination would maintain a low level of pertussis incidence in the long run for all age groups (respectively 30 and 20 cases per 100,000 person years. These strategies would also result in significant reductions of pertussis costs (between -77% and -80% including additional vaccination costs. The cocoon strategy complemented by a single booster dose is the most cost-effective one, whereas the decennial adult vaccination is slightly more effective in the long run. CONCLUSIONS: By providing a high level of disease control, the implementation of an adult vaccination program against pertussis appears to be highly cost-effective and often cost-saving.

  6. 3-D MDT with spherical targets by bilinear interpolation for determining blood velocity profiles including the vessel wall effect

    Science.gov (United States)

    Choomphon-anomakhun, Natthaphon; Natenapit, Mayuree

    2018-02-01

    A numerical simulation of three-dimensional (3-D) implant assisted-magnetic drug targeting (IA-MDT) using ferromagnetic spherical targets, including the effect from the vessel wall on the blood flow, is presented. The targets were implanted within arterioles and subjected to an externally uniform applied magnetic field in order to increase the effectiveness of targeting magnetic drug carrier particles (MDCPs). The capture area (As) of the MDCPs was determined by inspection of the particle trajectories simulated from the particle equations of motion. The blood flow velocities at any particle position around the target were obtained by applying bilinear interpolation to the numerical blood velocity data. The effects on As of the type of ferromagnetic materials in the targets and MDCPs, average blood flow rates, mass fraction of the ferromagnetic material in the MDCPs, average radii of MDCPs (Rp) and the externally applied magnetic field strength (μ0H0) were evaluated. Furthermore, the appropriate μ0H0 and Rp for the IA-MDT design is suggested. In the case of the SS409 target and magnetite MDCPs, dimensionless capture areas ranging from 4.1- to 12.4 and corresponding to particle capture efficiencies of 31-94% were obtained with Rp ranging from 100- to 500 nm, weight fraction of 80%, μ0H0 of 0.6 T and an average blood flow rate of 0.01 ms-1. In addition, the more general 3-D modelling of IA-MDT in this work is applicable to IA-MDT using spherical targets implanted within blood vessels for both laminar and potential blood flows including the wall effect.

  7. Microwave frequency electromagnetic fields (EMFs) produce widespread neuropsychiatric effects including depression.

    Science.gov (United States)

    Pall, Martin L

    2016-09-01

    Non-thermal microwave/lower frequency electromagnetic fields (EMFs) act via voltage-gated calcium channel (VGCC) activation. Calcium channel blockers block EMF effects and several types of additional evidence confirm this mechanism. Low intensity microwave EMFs have been proposed to produce neuropsychiatric effects, sometimes called microwave syndrome, and the focus of this review is whether these are indeed well documented and consistent with the known mechanism(s) of action of such EMFs. VGCCs occur in very high densities throughout the nervous system and have near universal roles in release of neurotransmitters and neuroendocrine hormones. Soviet and Western literature shows that much of the impact of non-thermal microwave exposures in experimental animals occurs in the brain and peripheral nervous system, such that nervous system histology and function show diverse and substantial changes. These may be generated through roles of VGCC activation, producing excessive neurotransmitter/neuroendocrine release as well as oxidative/nitrosative stress and other responses. Excessive VGCC activity has been shown from genetic polymorphism studies to have roles in producing neuropsychiatric changes in humans. Two U.S. government reports from the 1970s to 1980s provide evidence for many neuropsychiatric effects of non-thermal microwave EMFs, based on occupational exposure studies. 18 more recent epidemiological studies, provide substantial evidence that microwave EMFs from cell/mobile phone base stations, excessive cell/mobile phone usage and from wireless smart meters can each produce similar patterns of neuropsychiatric effects, with several of these studies showing clear dose-response relationships. Lesser evidence from 6 additional studies suggests that short wave, radio station, occupational and digital TV antenna exposures may produce similar neuropsychiatric effects. Among the more commonly reported changes are sleep disturbance/insomnia, headache, depression

  8. Electron Beam Adjustment in PLATO RTS 2 Including the Effect of Air Gaps

    CERN Document Server

    Lopes, M C; Trindade, A; Rodrigues, P; Peralta, L

    2002-01-01

    Background and Purpose: Beam characterization for electron dose calculations in PLATO RTS 2 treatment planning system requires the tuning of two adjustment parameters: sqx (the initial angular spread) and FMCS (a "fudge" multiple Coulomb scattering parameter). This work provides a set of suggestions to optimise electron dose calculations with PLATO, taking into account the effect of air gaps between the electron applicator and the patient skin. Material and Methods: Two adjustment criteria have been followed: one which uses just one input data set corresponding to the standard (null) air gap and another one that takes into account the whole range of clinically used distances between the electron applicator and the patient surface. The adjusted values of sqx were compared with experimental data and GEANT3 Monte Carlo code results. A systematic study has been carried out of the effect of both adjustment parameters on electron dose calculations in water. Comparisons of dose distributions and point dose values ha...

  9. Lattice Thermal Conductivity of Polyethylene Molecular Crystals from First-Principles Including Nuclear Quantum Effects.

    Science.gov (United States)

    Shulumba, Nina; Hellman, Olle; Minnich, Austin J

    2017-11-03

    Molecular crystals such as polyethylene are of intense interest as flexible thermal conductors, yet their intrinsic upper limits of thermal conductivity remain unknown. Here, we report a study of the vibrational properties and lattice thermal conductivity of a polyethylene molecular crystal using an ab initio approach that rigorously incorporates nuclear quantum motion and finite temperature effects. We obtain a thermal conductivity along the chain direction of around 160  W m^{-1} K^{-1} at room temperature, providing a firm upper bound for the thermal conductivity of this molecular crystal. Furthermore, we show that the inclusion of quantum nuclear effects significantly impacts the thermal conductivity by altering the phase space for three-phonon scattering. Our computational approach paves the way for ab initio studies and computational material discovery of molecular solids free of any adjustable parameters.

  10. Including children with autism in general education classrooms. A review of effective strategies.

    Science.gov (United States)

    Harrower, J K; Dunlap, G

    2001-10-01

    Children with autism can benefit from participation in inclusive classroom environments, and many experts assert that inclusion is a civil right and is responsible for nurturing appropriate social development. However, most children with autism require specialized supports to experience success in these educational contexts. This article provides a review of the empirical research that has addressed procedures for promoting successful inclusion of students with autism. Strategies reviewed include antecedent manipulations, delayed contingencies, self-management, peer-mediated interventions, and other approaches that have been demonstrated in the literature to be useful. The article concludes with a discussion of future research needs.

  11. Brain function and glucocorticoids in obesity and type 2 diabetes including effects of lifestyle interventions

    OpenAIRE

    Stomby, Andreas

    2015-01-01

    Background Obesity and associated metabolic dysregulation are linked to impaired cognitive function and alterations in brain structure, which increases the risk of age-related dementia. Increased glucocorticoid (GC) exposure may be a potential mediator of these negative effects on the brain. Methods and results In paper 1, we tested the relationship between cortisol levels, brain morphology and cognitive function in 200 women and men. Salivary cortisol levels were negatively related to cortic...

  12. pH-Free Measurement of Relative Acidities, Including Isotope Effects.

    Science.gov (United States)

    Perrin, Charles L

    2017-01-01

    A powerful pH-free multicomponent NMR titration method can measure relative acidities, even of closely related compounds, with excellent accuracy. The history of the method is presented, along with details of its implementation and a comparison with earlier NMR titrations using a pH electrode. Many of its areas of applicability are described, especially equilibrium isotope effects. The advantages of the method, some practical considerations, and potential pitfalls are considered. © 2017 Elsevier Inc. All rights reserved.

  13. Heat transfer behavior including thermal wake effects in forced air cooling of arrays of rectangular blocks

    International Nuclear Information System (INIS)

    Sridhar, S.; Faghri, M.; Lessmann, R.C.

    1990-01-01

    Experiments have been carried out to study thermal wake effects in arrays of rectangular blocks encountered in electronic equipment. Data were obtained for a series of channel heights and flow velocities. The temperature rise due to wake effects behind a single heated module was found to be fairly independent of the channel height and the position of the heated block, for a given approach velocity. The adiabatic temperature rise data for a module due to a heated element immediately upstream of it for different inter-module spacings were found to correlate well in terms of a new parameter called the surface packing density. This paper reports that it was reported by the authors in an earlier paper that both the adiabatic heat transfer coefficient nd pressure-drop data for regular in-line arrays correlated well in terms of a composite geometric parameter called the column packing density. These experiments have been extended to a higher Reynolds number. Empirical correlations are presented here for friction factor and Nusselt number in terms of the volume packing density, and for the thermal wake effects in terms of the surface packing density. Data from literature for arrays with widely different geometric parameters are shown to agree with these correlations

  14. Quantified, Interactive Simulation of AMCW ToF Camera Including Multipath Effects

    Directory of Open Access Journals (Sweden)

    David Bulczak

    2017-12-01

    Full Text Available In the last decade, Time-of-Flight (ToF range cameras have gained increasing popularity in robotics, automotive industry, and home entertainment. Despite technological developments, ToF cameras still suffer from error sources such as multipath interference or motion artifacts. Thus, simulation of ToF cameras, including these artifacts, is important to improve camera and algorithm development. This paper presents a physically-based, interactive simulation technique for amplitude modulated continuous wave (AMCW ToF cameras, which, among other error sources, includes single bounce indirect multipath interference based on an enhanced image-space approach. The simulation accounts for physical units down to the charge level accumulated in sensor pixels. Furthermore, we present the first quantified comparison for ToF camera simulators. We present bidirectional reference distribution function (BRDF measurements for selected, purchasable materials in the near-infrared (NIR range, craft real and synthetic scenes out of these materials and quantitatively compare the range sensor data.

  15. A graphic approach to include dissipative-like effects in reversible thermal cycles

    Science.gov (United States)

    Gonzalez-Ayala, Julian; Arias-Hernandez, Luis Antonio; Angulo-Brown, Fernando

    2017-05-01

    Since the decade of 1980's, a connection between a family of maximum-work reversible thermal cycles and maximum-power finite-time endoreversible cycles has been established. The endoreversible cycles produce entropy at their couplings with the external heat baths. Thus, this kind of cycles can be optimized under criteria of merit that involve entropy production terms. Meanwhile the relation between the concept of work and power is quite direct, apparently, the finite-time objective functions involving entropy production have not reversible counterparts. In the present paper we show that it is also possible to establish a connection between irreversible cycle models and reversible ones by means of the concept of "geometric dissipation", which has to do with the equivalent role of a deficit of areas between some reversible cycles and the Carnot cycle and actual dissipative terms in a Curzon-Ahlborn engine.

  16. Anti-diabetic effects including diabetic nephropathy of anti-osteoporotic trace minerals on diabetic mice.

    Science.gov (United States)

    Maehira, Fusako; Ishimine, Nau; Miyagi, Ikuko; Eguchi, Yukinori; Shimada, Katsumasa; Kawaguchi, Daisuke; Oshiro, Yoshihide

    2011-04-01

    In our previous study to evaluate the effects of soluble silicon (Si) on bone metabolism, Si and coral sand (CS) as a natural Si-containing material suppressed peroxisome proliferator-activated receptor γ (PPARγ), which regulates both glucose and bone metabolism and increases adipogenesis at the expense of osteogenesis, leading to bone loss. In this study, we investigated the anti-diabetic effects of bone-seeking elements, Si and stable strontium (Sr), and CS as a natural material containing these elements using obese diabetic KKAy mice. Weanling male mice were fed diets containing 1% Ca supplemented with CaCO(3) as the control and CS, and diets supplemented with 50 ppm Si or 750 ppm Sr to control diet for 56 d. The mRNA expressions related to energy expenditure in the pancreas and kidney were quantified by real-time polymerase chain reaction. At the end of feeding, plasma glucose, insulin, leptin, and adiponectin levels decreased significantly in three test groups, while pancreatic PPARγ and adiponectin mRNA expression levels increased significantly toward the normal level, improving the glucose sensitivity of β-cells and inducing a significant decrease in insulin expression. The renal PPARγ, PPARα, and adiponectin expression levels, histologic indices of diabetic glomerulopathy, and plasma indices of renal function were also improved significantly in the test groups. Taken together, anti-osteoporotic trace minerals, Si and Sr, and CS containing them showed novel anti-diabetic effects of lowering blood glucose level, improving the tolerance to insulin, leptin, and adiponectin, and reducing the risk of glomerulopathy through modulation of related gene expression in the pancreas and kidney. Copyright © 2011 Elsevier Inc. All rights reserved.

  17. Multiple Crack Growth Prediction in AA2024-T3 Friction Stir Welded Joints, Including Manufacturing Effects

    DEFF Research Database (Denmark)

    Carlone, Pierpaolo; Citarella, Roberto; Sonne, Mads Rostgaard

    2016-01-01

    A great deal of attention is currently paid by several industries toward the friction stir welding process to realize lightweight structures. Within this aim, the realistic prediction of fatigue behavior of welded assemblies is a key factor. In this work an integrated finite element method - dual...... boundary element method (FEM-DBEM) procedure, coupling the welding process simulation to the subsequent crack growth assessment, is proposed and applied to simulate multiple crack propagation, with allowance for manufacturing effects. The friction stir butt welding process of the precipitation hardened AA...

  18. Path-integral calculation of the second virial coefficient including intramolecular flexibility effects

    Energy Technology Data Exchange (ETDEWEB)

    Garberoglio, Giovanni, E-mail: garberoglio@fbk.eu [Interdisciplinary Laboratory for Computational Science (LISC), FBK-CMM and University of Trento, via Sommarive 18, I-38123 Povo (Italy); Jankowski, Piotr [Department of Quantum Chemistry, Faculty of Chemistry, Nicolaus Copernicus University, Gagarina 7, PL-87-100 Toruń (Poland); Szalewicz, Krzysztof [Department of Physics and Astronomy, University of Delaware, Newark, Delaware 19716 (United States); Harvey, Allan H. [Applied Chemicals and Materials Division, National Institute of Standards and Technology, 325 Broadway, Boulder, Colorado 80305-3337 (United States)

    2014-07-28

    We present a path-integral Monte Carlo procedure for the fully quantum calculation of the second molecular virial coefficient accounting for intramolecular flexibility. This method is applied to molecular hydrogen (H{sub 2}) and deuterium (D{sub 2}) in the temperature range 15–2000 K, showing that the effect of molecular flexibility is not negligible. Our results are in good agreement with experimental data, as well as with virials given by recent empirical equations of state, although some discrepancies are observed for H{sub 2} between 100 and 200 K.

  19. Specialists meeting on properties of primary circuit structural materials including environmental effects

    International Nuclear Information System (INIS)

    1977-01-01

    The Specialists Meeting on Properties of Primary Circuit Structural Materials of LMFBRs covered the following topics: overview of materials program in different countries; mechanical properties of materials in air; fracture mechanics studies - component related activities; impact of environmental influences on mechanical properties; relationship of material properties and design methods. The purpose of the meeting was to provide a forum for exchange of information on structural materials behaviour in primary circuit of fast breeder reactors. Special emphasis was placed on environmental effects such as influence of sodium and irradiation on mechanical properties of reactor materials

  20. Treatment effects in the prostate including those associated with traditional and emerging therapies.

    Science.gov (United States)

    Evans, Andrew J; Ryan, Paul; Van derKwast, Theodorus

    2011-07-01

    Classic treatment options for prostate cancer consist of radical prostatectomy, antiandrogen (or hormonal) therapy, and radiation therapy. Hormonal and radiation therapy, in particular, have well known, often profound effects on the histologic appearance of benign prostate tissue and prostatic carcinoma. The tissue changes induced by these treatments have been comprehensively described in several sources. Novel therapies ranging from focal ablative treatments to highly targeted molecular therapies are beginning to emerge and pathologists will play a central role in documenting the effects of these treatments on normal and malignant prostate tissue. It is therefore important that pathologists have access to basic treatment information and a solid working knowledge of the morphologic changes induced by these therapies. This will ensure accurate interpretation and reporting of posttreatment prostate specimens. This review is based on a presentation given by Dr A. Evans at the International Society of Urological Pathology Companion Society Meeting (Hot Topics in Urological Pathology) at The United States Canadian Academy of Pathology Meeting in Washington DC on March 20, 2010. This review will cover the histopathologic features seen in benign prostate tissue and prostatic carcinoma seen following: hormonal therapy, radiation therapy, ablative therapies such as vascular-targeted photodynamic therapy, interstitial laser thermotherapy, and high-intensity focussed ultrasound. An emphasis is placed on these specific modalities as they are currently in use as primary, salvage, or investigational therapy in the treatment of prostate cancer.

  1. NLO QCD+EW predictions for HV and HV +jet production including parton-shower effects

    Science.gov (United States)

    Granata, F.; Lindert, J. M.; Oleari, C.; Pozzorini, S.

    2017-09-01

    We present the first NLO QCD+EW predictions for Higgs boson production in association with a ℓν ℓ or ℓ + ℓ - pair plus zero or one jets at the LHC. Fixed-order NLO QCD+EW calculations are combined with a QCD+QED parton shower using the recently developed resonance-aware method in the POWHEG framework. Moreover, applying the improved MiNLO technique to Hℓν ℓ +jet and Hℓ + ℓ - +jet production at NLO QCD+EW, we obtain predictions that are NLO accurate for observables with both zero or one resolved jet. This approach permits also to capture higher-order effects associated with the interplay of EW corrections and QCD radiation. The behavior of EW corrections is studied for various kinematic distributions, relevant for experimental analyses of Higgsstrahlung processes at the 13 TeV LHC. Exact NLO EW corrections are complemented with approximate analytic formulae that account for the leading and next-to-leading Sudakov logarithms in the high-energy regime. In the tails of transverse-momentum distributions, relevant for analyses in the boosted Higgs regime, the Sudakov approximation works well, and NLO EW effects can largely exceed the ten percent level. Our predictions are based on the POWHEG BOX RES+OpenLoops framework in combination with the Pythia 8.1 parton shower.

  2. Gender differences in episodic memory and visual working memory including the effects of age.

    Science.gov (United States)

    Pauls, Franz; Petermann, Franz; Lepach, Anja Christina

    2013-01-01

    Analysing the relationship between gender and memory, and examining the effects of age on the overall memory-related functioning, are the ongoing goals of psychological research. The present study examined gender and age group differences in episodic memory with respect to the type of task. In addition, these subgroup differences were also analysed in visual working memory. A sample of 366 women and 330 men, aged between 16 and 69 years of age, participated in the current study. Results indicate that women outperformed men on auditory memory tasks, whereas male adolescents and older male adults showed higher level performances on visual episodic and visual working memory measures. However, the size of gender-linked effects varied somewhat across age groups. Furthermore, results partly support a declining performance on episodic memory and visual working memory measures with increasing age. Although age-related losses in episodic memory could not be explained by a decreasing verbal and visuospatial ability with age, women's advantage in auditory episodic memory could be explained by their advantage in verbal ability. Men's higher level visual episodic memory performance was found to result from their advantage in visuospatial ability. Finally, possible methodological, biological, and cognitive explanations for the current findings are discussed.

  3. Comprehensive study in the inhibitory effect of berberine on gene transcription, including TATA box.

    Science.gov (United States)

    Wang, Yugang; Kheir, Michael M; Chai, Yushuang; Hu, Jun; Xing, Dongming; Lei, Fan; Du, Lijun

    2011-01-01

    Berberine (BBR) is an established natural DNA intercalator with numerous pharmacological functions. However, currently there are neither detailed reports concerning the distribution of this alkaloid in living cells nor reports concerning the relationship between BBR's association with DNA and the function of DNA. Here we report that the distribution of BBR within the nucleus can be observed 30 minutes after drug administration, and that the content of berberine in the nucleus peaks at around 4 µmol, which is twelve hours after drug administration. The spatial conformation of DNA and chromatin was altered immediately after their association with BBR. Moreover, this association can effectively suppress the transcription of DNA in living cell systems and cell-free systems. Electrophoretic mobility shift assays (EMSA) demonstrated further that BBR can inhibit the association between the TATA binding protein (TBP) and the TATA box in the promoter, and this finding was also attained in living cells by chromatin immunoprecipitation (ChIP). Based on results from this study, we hypothesize that berberine can suppress the transcription of DNA in living cell systems, especially suppressing the association between TBP and the TATA box by binding with DNA and, thus, inhibiting TATA box-dependent gene expression in a non-specific way. This novel study has significantly expanded the sphere of knowledge concerning berberine's pharmacological effects, beginning at its paramount initial interaction with the TATA box.

  4. Development of a CFD Model Including Tree's Drag Parameterizations: Application to Pedestrian's Wind Comfort in an Urban Area

    Science.gov (United States)

    Kang, G.; Kim, J.

    2017-12-01

    This study investigated the tree's effect on wind comfort at pedestrian height in an urban area using a computational fluid dynamics (CFD) model. We implemented the tree's drag parameterization scheme to the CFD model and validated the simulated results against the wind-tunnel measurement data as well as LES data via several statistical methods. The CFD model underestimated (overestimated) the concentrations on the leeward (windward) walls inside the street canyon in the presence of trees, because the CFD model can't resolve the latticed cage and can't reflect the concentration increase and decrease caused by the latticed cage in the simulations. However, the scalar pollutants' dispersion simulated by the CFD model was quite similar to that in the wind-tunnel measurement in pattern and magnitude, on the whole. The CFD model overall satisfied the statistical validation indices (root normalized mean square error, geometric mean variance, correlation coefficient, and FAC2) but failed to satisfy the fractional bias and geometric mean bias due to the underestimation on the leeward wall and overestimation on the windward wall, showing that its performance was comparable to the LES's performance. We applied the CFD model to evaluation of the trees' effect on the pedestrian's wind-comfort in an urban area. To investigate sensory levels for human activities, the wind-comfort criteria based on Beaufort wind-force scales (BWSs) were used. In the tree-free scenario, BWS 4 and 5 (unpleasant condition for sitting long and sitting short, respectively) appeared in the narrow spaces between buildings, in the upwind side of buildings, and the unobstructed areas. In the tree scenario, BWSs decreased by 1 3 grade inside the campus of Pukyong National University located in the target area, which indicated that trees planted in the campus effectively improved pedestrian's wind comfort.

  5. Possible Simple Structures of the Universe to Include General Relativity Effects

    Directory of Open Access Journals (Sweden)

    Corneliu BERBENTE

    2017-12-01

    Full Text Available The general relativity describes the universe properties, the gravity playing a fundamental role. One uses a metric tensor in a Riemann space, g  , which should be in agreement with a mass (or energy tensor in order to satisfy the Einstein equation of the general relativity [1]. This equation contains the Ricci curvature as well. In general, applications are done considering that a chosen metric is valid without region limits. In fact, the density of the energy whose distribution is however unknown is variable in universe; therefore, the metrics need to be adapted to different regions. For this reason one suggests to start with a simple, average mass-energy distribution that could represent in a first step the actual universe. This suggestion is in agreement with the symmetrical distribution of equal spheres existing in a model of the early universe given by one of the authors. Two kinds of distribution are given. The possibility of black holes formation is studied and a criterion is given.

  6. Specificity of psychomotor reactions in the conditions of support deprivation including effects of countermeasures

    Science.gov (United States)

    Nichiporuk, Igor; Ivanov, Oleg

    Activity of the cosmonaut demands high level of psychomotor reactions (PMR) which can vary during space flight under the influences of psychophysiological state’s variability and unusual inhabitancy that causes the necessity of PMR estimation’s inclusion into quality monitoring of capacity for work (CW). A main objective of research was a study of features of visual-motor reactions (VMR) and elements of CW of the person within simulation of microgravity effects via 7-day dry immersion (DI) in healthy male-volunteers 20-35 years old. The experimental data were received which testified to peculiarities of VMR and recognition of simple figures of main colors of a visible spectrum (red, green, blue, the RGB-standard) in the conditions of the DI characterized by support deprivation and decreased proprioceptive afferentation - in a control series and in a series with use of mioelectrostimulation as a countermeasure.

  7. Bifurcation of space-charge wave in a plasma waveguide including the wake potential effect

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Myoung-Jae [Department of Physics and Research Institute for Natural Sciences, Hanyang University, Seoul 04763 (Korea, Republic of); Jung, Young-Dae, E-mail: ydjung@hanyang.ac.kr [Department of Applied Physics and Department of Bionanotechnology, Hanyang University, Ansan, Kyunggi-Do 15588, South Korea and Department of Physics, Applied Physics, and Astronomy, Rensselaer Polytechnic Institute, 110 8th Street, Troy, New York 12180-3590 (United States)

    2016-09-15

    The wake potential effects on the propagation of the space-charge dust ion-acoustic wave are investigated in a cylindrically bounded dusty plasma with the ion flow. The results show that the wake potential would generate the double frequency modes in a cylindrically bounded dusty plasma. It is found that the upper mode of the wave frequency with the root of higher-order is smaller than that with the root of lower-order in intermediate wave number domains. However, the lower mode of the scaled wave frequency with the root of higher-order is found to be greater than that with the root of lower-order. It is found that the influence in the order of the root of the Bessel function on the wave frequency of the space-charge dust-ion-acoustic wave in a cylindrically confined dusty plasma decreases with an increase in the propagation wave number. It is also found that the double frequency modes increase with increasing Mach number due to the ion flow in a cylindrical dusty plasma. In addition, it is found that the upper mode of the group velocity decreases with an increase in the scaled radius of the plasma cylinder. However, it is shown that the lower mode of the scaled group velocity of the space-charge dust ion acoustic wave increases with an increase in the radius of the plasma cylinder. The variation of the space-charge dust-ion-acoustic wave due to the wake potential and geometric effects is also discussed.

  8. Estimating eligibility for lung cancer screening in an Australian cohort, including the effect of spirometry.

    Science.gov (United States)

    Manners, David; Hui, Jennie; Hunter, Michael; James, Alan; Knuiman, Matthew W; McWilliams, Annette; Mulrennan, Siobhain; Musk, Arthur W Bill; Brims, Fraser Jh

    2016-06-20

    To estimate the proportion of ever-smokers who are eligible for lung cancer screening in an Australian cohort, and to evaluate the effect of spirometry in defining chronic obstructive pulmonary disease (COPD) when assessing screening eligibility. Cross-sectional study of 3586 individuals aged 50-68 years who live in the Busselton Shire of Western Australia. Proportion of ever-smokers eligible for lung cancer screening based on United States Preventive Services Task Force (USPSTF) criteria, and PLCOm2012 lung cancer risk > 1.5%. The effect of using self-reported COPD, symptoms consistent with COPD, or spirometry to define COPD for screening eligibility according to the PLCOm2012 criteria. Of ever-smokers aged 55-68 years, 254 (20.1%) would be eligible for screening according to USPSTF criteria; fewer would be eligible according to PLCOm2012 criteria (225, 17.9%; P = 0.004). This is equivalent to 8.9-10.0% of the total population aged 55-68 years, which suggests about 450 000 individuals in Australia may be eligible for lung cancer screening. The proportions of eligible participants were not significantly different whether spirometry results or symptoms consistent with COPD were used to determine PLCOm2012 risk. The proportion of ever-smokers in this population who were eligible for lung cancer screening was 17.9-20.1%. Using symptoms to define COPD is an appropriate surrogate measure for spirometry when determining the presence of COPD in this population. There are significant challenges for policy makers on how to identify and recruit these eligible individuals from the wider population.

  9. Isogeometric analysis of free-form Timoshenko curved beams including the nonlinear effects of large deformations

    Science.gov (United States)

    Hosseini, Seyed Farhad; Hashemian, Ali; Moetakef-Imani, Behnam; Hadidimoud, Saied

    2018-03-01

    In the present paper, the isogeometric analysis (IGA) of free-form planar curved beams is formulated based on the nonlinear Timoshenko beam theory to investigate the large deformation of beams with variable curvature. Based on the isoparametric concept, the shape functions of the field variables (displacement and rotation) in a finite element analysis are considered to be the same as the non-uniform rational basis spline (NURBS) basis functions defining the geometry. The validity of the presented formulation is tested in five case studies covering a wide range of engineering curved structures including from straight and constant curvature to variable curvature beams. The nonlinear deformation results obtained by the presented method are compared to well-established benchmark examples and also compared to the results of linear and nonlinear finite element analyses. As the nonlinear load-deflection behavior of Timoshenko beams is the main topic of this article, the results strongly show the applicability of the IGA method to the large deformation analysis of free-form curved beams. Finally, it is interesting to notice that, until very recently, the large deformations analysis of free-form Timoshenko curved beams has not been considered in IGA by researchers.

  10. Extensions of the Rosner-Colditz breast cancer prediction model to include older women and type-specific predicted risk.

    Science.gov (United States)

    Glynn, Robert J; Colditz, Graham A; Tamimi, Rulla M; Chen, Wendy Y; Hankinson, Susan E; Willett, Walter W; Rosner, Bernard

    2017-08-01

    A breast cancer risk prediction rule previously developed by Rosner and Colditz has reasonable predictive ability. We developed a re-fitted version of this model, based on more than twice as many cases now including women up to age 85, and further extended it to a model that distinguished risk factor prediction of tumors with different estrogen/progesterone receptor status. We compared the calibration and discriminatory ability of the original, the re-fitted, and the type-specific models. Evaluation used data from the Nurses' Health Study during the period 1980-2008, when 4384 incident invasive breast cancers occurred over 1.5 million person-years. Model development used two-thirds of study subjects and validation used one-third. Predicted risks in the validation sample from the original and re-fitted models were highly correlated (ρ = 0.93), but several parameters, notably those related to use of menopausal hormone therapy and age, had different estimates. The re-fitted model was well-calibrated and had an overall C-statistic of 0.65. The extended, type-specific model identified several risk factors with varying associations with occurrence of tumors of different receptor status. However, this extended model relative to the prediction of any breast cancer did not meaningfully reclassify women who developed breast cancer to higher risk categories, nor women remaining cancer free to lower risk categories. The re-fitted Rosner-Colditz model has applicability to risk prediction in women up to age 85, and its discrimination is not improved by consideration of varying associations across tumor subtypes.

  11. Interpretation of vector magnetograph data including magneto-optic effects. Pt. 1

    International Nuclear Information System (INIS)

    West, E.A.; Hagyard, J.; National Aeronautics and Space Administration, Huntsville, AL

    1983-01-01

    In this paper, the presence of Faraday rotation in measurements of orientation of a sunspot's transvese magnetic field is investigated. Using observations obtained with the Marshall Space Flight Center's (MSFC) vector magnetograph, the derived vector magnetic field of a simple, symmetric sunspot is used to calculate the degree of Faraday rotation in the azimuth of the transverse field as a function of wavelength from analytical expressions for the Stokes parameters. These results are then compared with the observed rotation of the field's azimuth which is derived from observations at different wavelengths within the Fe sub(I) 5250 A spectral line. From these comparisons, we find: the observed rotation of the azimuth is simulated to a reasonable degree by the theoretical formulations if the line-formation parameter eta 0 is varied over the sunspot; these variations in eta 0 are substantiated by the line-intensity data; for the MSFC system, Faraday rotation can be neglected for field strengths less than 1800 G and field inclinations greater than 45 0 ; to minimize the effects of Faraday rotation in sunspot umbrae, MSFC magnetograph measurements must be made in the far wings of the Zeeman-sensitive spectral line. (orig.)

  12. VERB-4D simulations of Earths inner magnetosphere: Ring-current-to-radiation-belt electrons including adiabatic effects in a realistic magnetic field

    Science.gov (United States)

    Kellerman, Adam; Shprits, Yuri; Drozdov, Alexander; Aseeve, Nikita

    2016-04-01

    The Versatile Electron Radiation Belt 4D (VERB-4D) code models the dynamics of ring-current to radiation-belt electrons in Earth's magnetosphere. The code has been developed further to include a realistic magnetic field model, which allows one to model MLT-dependent adiabatic effects, in addition to other processes. Initial results are presented for storm- and non-storm time periods, demonstrating the role which adiabatic variations play on the observed electron dynamics.

  13. Probabilistic and deterministic soil structure interaction analysis including ground motion incoherency effects

    Energy Technology Data Exchange (ETDEWEB)

    Elkhoraibi, T., E-mail: telkhora@bechtel.com; Hashemi, A.; Ostadan, F.

    2014-04-01

    Soil-structure interaction (SSI) is a major step for seismic design of massive and stiff structures typical of the nuclear facilities and civil infrastructures such as tunnels, underground stations, dams and lock head structures. Currently most SSI analyses are performed deterministically, incorporating limited range of variation in soil and structural properties and without consideration of the ground motion incoherency effects. This often leads to overestimation of the seismic response particularly the In-Structure-Response Spectra (ISRS) with significant impositions of design and equipment qualification costs, especially in the case of high-frequency sensitive equipment at stiff soil or rock sites. The reluctance to incorporate a more comprehensive probabilistic approach is mainly due to the fact that the computational cost of performing probabilistic SSI analysis even without incoherency function considerations has been prohibitive. As such, bounding deterministic approaches have been preferred by the industry and accepted by the regulatory agencies. However, given the recently available and growing computing capabilities, the need for a probabilistic-based approach to the SSI analysis is becoming clear with the advances in performance-based engineering and the utilization of fragility analysis in the decision making process whether by the owners or the regulatory agencies. This paper demonstrates the use of both probabilistic and deterministic SSI analysis techniques to identify important engineering demand parameters in the structure. A typical nuclear industry structure is used as an example for this study. The system is analyzed for two different site conditions: rock and deep soil. Both deterministic and probabilistic SSI analysis approaches are performed, using the program SASSI, with and without ground motion incoherency considerations. In both approaches, the analysis begins at the hard rock level using the low frequency and high frequency hard rock

  14. Sound propagation in narrow tubes including effects of viscothermal and turbulent damping with application to charge air coolers

    Science.gov (United States)

    Knutsson, Magnus; Åbom, Mats

    2009-02-01

    Charge air coolers (CACs) are used on turbocharged internal combustion engines to enhance the overall gas-exchange performance. The cooling of the charged air results in higher density and thus volumetric efficiency. It is also important for petrol engines that the knock margin increases with reduced charge air temperature. A property that is still not very well investigated is the sound transmission through a CAC. The losses, due to viscous and thermal boundary layers as well as turbulence, in the narrow cooling tubes result in frequency dependent attenuation of the transmitted sound that is significant and dependent on the flow conditions. Normally, the cross-sections of the cooling tubes are neither circular nor rectangular, which is why no analytical solution accounting for a superimposed mean flow exists. The cross-dimensions of the connecting tanks, located on each side of the cooling tubes, are large compared to the diameters of the inlet and outlet ducts. Three-dimensional effects will therefore be important at frequencies significantly lower than the cut-on frequencies of the inlet/outlet ducts. In this study the two-dimensional finite element solution scheme for sound propagation in narrow tubes, including the effect of viscous and thermal boundary layers, originally derived by Astley and Cummings [Wave propagation in catalytic converters: Formulation of the problem and finite element scheme, Journal of Sound and Vibration 188 (5) (1995) 635-657] is used to extract two-ports to represent the cooling tubes. The approximate solutions for sound propagation, accounting for viscothermal and turbulent boundary layers derived by Dokumaci [Sound transmission in narrow pipes with superimposed uniform mean flow and acoustic modelling of automobile catalytic converters, Journal of Sound and Vibration 182 (5) (1995) 799-808] and Howe [The damping of sound by wall turbulent shear layers, Journal of the Acoustical Society of America 98 (3) (1995) 1723-1730], are

  15. Effects of vitamins, including vitamin A, on HIV/AIDS patients.

    Science.gov (United States)

    Mehta, Saurabh; Fawzi, Wafaie

    2007-01-01

    increase lymphoid cell differentiation, which leads to an increase in CCR5 receptors. These receptors are essential for attachment of HIV to the lymphocytes and therefore, an increase in their number is likely to increase HIV replication. Vitamin A supplementation in HIV-infected children, on the other hand, has been associated with protective effects against mortality and morbidity, similar to that seen in HIV-negative children. The risk for lower respiratory tract infection and severe watery diarrhea has been shown to be lower in HIV-infected children supplemented with vitamin A. All-cause mortality and AIDS-related deaths have also been found to be lower in vitamin A-supplemented HIV-infected children. The benefits of multivitamin supplementation, particularly vitamins B, C, and E, have been more consistent across studies. Multivitamin supplementation in HIV-infected pregnant mothers has been shown to reduce the incidence of adverse pregnancy outcomes such as fetal loss and low birth weight. It also has been shown to decrease rates of MTCT among women who have poor nutritional or immunologic status. Further, multivitamin supplementation reduces the rate of HIV disease progression among patients in early stage of disease, thus delaying the need for ART by prolonging the pre-ART stage. In brief, there is no evidence to recommend vitamin A supplementation of HIV-infected pregnant women; however, periodic vitamin A supplementation of HIV-infected infants and children is beneficial in reducing all-cause mortality and morbidity and is recommended. Similarly, multivitamin supplementation of people infected with HIV, particularly pregnant women, is strongly suggested.

  16. Unified model to the Tungsten inert Gas welding process including the cathode, the plasma and the anode

    International Nuclear Information System (INIS)

    Brochard, M.

    2009-06-01

    During this work, a 2D axially symmetric model of a TIG arc welding process had been developed in order to predict for given welding parameters, the needed variables for a designer of welded assembly: the heat input on the work piece, the weld pool geometry,... The developed model, using the Cast3M finite elements software, deals with the physical phenomena acting in each part of the process: the cathode, the plasma, the work piece with a weld pool, and the interfaces between these parts. To solve this model, the thermohydraulics equations are coupled with the electromagnetic equations that are calculated in part using the least squares finite element method. The beginning of the model validation consisted in comparing the results obtained with the ones available in the scientific literature. Thus, this step points out the action of each force in the weld pool, the contribution of each heat flux in the energy balance. Finally, to validate the model predictiveness, experimental and numerical sensitivity analyses were conducted using a design of experiments approach. The effects of the process current, the arc gap and the electrode tip angle on the weld pool geometry and the energy transferred to the work piece and the arc efficiency were studied. The good agreement obtained by the developed model for these outputs shows the good reproduction of the process physics. (author)

  17. Cost-Effectiveness of Including a Nurse Specialist in the Treatment of Urinary Incontinence in Primary Care in the Netherlands.

    Directory of Open Access Journals (Sweden)

    K M Holtzer-Goor

    Full Text Available Incontinence is an important health problem. Effectively treating incontinence could lead to important health gains in patients and caregivers. Management of incontinence is currently suboptimal, especially in elderly patients. To optimise the provision of incontinence care a global optimum continence service specification (OCSS was developed. The current study evaluates the costs and effects of implementing this OCSS for community-dwelling patients older than 65 years with four or more chronic diseases in the Netherlands.A decision analytic model was developed comparing the current care pathway for urinary incontinence in the Netherlands with the pathway as described in the OCSS. The new care strategy was operationalised as the appointment of a continence nurse specialist (NS located with the general practitioner (GP. This was assumed to increase case detection and to include initial assessment and treatment by the NS. The analysis used a societal perspective, including medical costs, containment products (out-of-pocket and paid by insurer, home care, informal care, and implementation costs.With the new care strategy a QALY gain of 0.005 per patient is achieved while saving €402 per patient over a 3 year period from a societal perspective. In interpreting these findings it is important to realise that many patients are undetected, even in the new care situation (36%, or receive care for containment only. In both of these groups no health gains were achieved.Implementing the OCSS in the Netherlands by locating a NS in the GP practice is likely to reduce incontinence, improve quality of life, and reduce costs. Furthermore, the study also highlighted that various areas of the continence care process lack data, which would be valuable to collect through the introduction of the NS in a study setting.

  18. Analysis of Two Stroke Marine Diesel Engine Operation Including Turbocharger Cut-Out by Using a Zero-Dimensional Model

    Directory of Open Access Journals (Sweden)

    Cong Guan

    2015-06-01

    Full Text Available In this article, the operation of a large two-stroke marine diesel engine including various cases with turbocharger cut-out was thoroughly investigated by using a modular zero-dimensional engine model built in MATLAB/Simulink environment. The model was developed by using as a basis an in-house modular mean value engine model, in which the existing cylinder block was replaced by a more detailed one that is capable of representing the scavenging ports-cylinder-exhaust valve processes. Simulation of the engine operation at steady state conditions was performed and the derived engine performance parameters were compared with the respective values obtained by the engine shop trials. The investigation of engine operation under turbocharger cut-out conditions in the region from 10% to 50% load was carried out and the influence of turbocharger cut-out on engine performance including the in-cylinder parameters was comprehensively studied. The recommended schedule for the combination of the turbocharger cut-out and blower activation was discussed for the engine operation under part load conditions. Finally, the influence of engine operating strategies on the annual fuel savings, CO2 emissions reduction and blower operating hours for a Panamax container ship operating at slow steaming conditions is presented and discussed.

  19. Poroviscoelastic finite element model including continuous fiber distribution for the simulation of nanoindentation tests on articular cartilage.

    Science.gov (United States)

    Taffetani, M; Griebel, M; Gastaldi, D; Klisch, S M; Vena, P

    2014-04-01

    Articular cartilage is a soft hydrated tissue that facilitates proper load transfer in diarthroidal joints. The mechanical properties of articular cartilage derive from its structural and hierarchical organization that, at the micrometric length scale, encompasses three main components: a network of insoluble collagen fibrils, negatively charged macromolecules and a porous extracellular matrix. In this work, a constituent-based constitutive model for the simulation of nanoindentation tests on articular cartilage is presented: it accounts for the multi-constituent, non-linear, porous, and viscous aspects of articular cartilage mechanics. In order to reproduce the articular cartilage response under different loading conditions, the model considers a continuous distribution of collagen fibril orientation, swelling, and depth-dependent mechanical properties. The model's parameters are obtained by fitting published experimental data for the time-dependent response in a stress relaxation unconfined compression test on adult bovine articular cartilage. Then, model validation is obtained by simulating three independent experimental tests: (i) the time-dependent response in a stress relaxation confined compression test, (ii) the drained response of a flat punch indentation test and (iii) the depth-dependence of effective Poisson's ratio in a unconfined compression test. Finally, the validated constitutive model has been used to simulate multiload spherical nanoindentation creep tests. Upon accounting for strain-dependent tissue permeability and intrinsic viscoelastic properties of the collagen network, the model accurately fits the drained and undrained curves and time-dependent creep response. The results show that depth-dependent tissue properties and glycosaminoglycan-induced tissue swelling should be accounted for when simulating indentation experiments. Copyright © 2013 Elsevier Ltd. All rights reserved.

  20. 50 CFR 23.15 - How may I travel internationally with my personal or household effects, including tourist souvenirs?

    Science.gov (United States)

    2010-10-01

    ... personal or household effects, including tourist souvenirs? 23.15 Section 23.15 Wildlife and Fisheries..., including tourist souvenirs? (a) Purpose. Article VII(3) of the Treaty recognizes a limited exemption for... if one of the following applies: (1) The Management Authority of the importing, exporting, or re...

  1. A quasi-static algorithm that includes effects of characteristic time scales for simulating failures in brittle materials

    KAUST Repository

    Liu, Jinxing

    2013-04-24

    When the brittle heterogeneous material is simulated via lattice models, the quasi-static failure depends on the relative magnitudes of Telem, the characteristic releasing time of the internal forces of the broken elements and Tlattice, the characteristic relaxation time of the lattice, both of which are infinitesimal compared with Tload, the characteristic loading period. The load-unload (L-U) method is used for one extreme, Telem << Tlattice, whereas the force-release (F-R) method is used for the other, Telem T lattice. For cases between the above two extremes, we develop a new algorithm by combining the L-U and the F-R trial displacement fields to construct the new trial field. As a result, our algorithm includes both L-U and F-R failure characteristics, which allows us to observe the influence of the ratio of Telem to Tlattice by adjusting their contributions in the trial displacement field. Therefore, the material dependence of the snap-back instabilities is implemented by introducing one snap-back parameter γ. Although in principle catastrophic failures can hardly be predicted accurately without knowing all microstructural information, effects of γ can be captured by numerical simulations conducted on samples with exactly the same microstructure but different γs. Such a same-specimen-based study shows how the lattice behaves along with the changing ratio of the L-U and F-R components. © 2013 The Author(s).

  2. Rating of Included Trials on the Efficacy–Effectiveness Spectrum : development of a new tool for systematic reviews

    NARCIS (Netherlands)

    Wieland, L. Susan; Berman, Brian M.; Altman, Douglas G.; Barth, Jürgen; Bouter, Lex M.; D'Adamo, Christopher R.; Linde, Klaus; Moher, David; Mullins, C. Daniel; Treweek, Shaun; Tunis, Sean; van der Windt, Danielle A.; Zwarenstein, Merrick; Witt, Claudia

    2017-01-01

    Background and Objective Randomized trials may be designed to provide evidence more strongly related to efficacy or effectiveness of an intervention. When systematic reviews are used to inform clinical or policy decisions, it is important to know the efficacy–effectiveness nature of the included

  3. The Evaporation and Survival of Cluster Galaxy Coronae. I. The Effectiveness of Isotropic Thermal Conduction Including Saturation

    Energy Technology Data Exchange (ETDEWEB)

    Vijayaraghavan, Rukmani; Sarazin, Craig, E-mail: rukmani@virginia.edu [Department of Astronomy, University of Virginia, 530 McCormick Rd., Charlottesville, VA 22904 (United States)

    2017-05-20

    We simulate the evolution of cluster galaxy hot interstellar medium (ISM) gas that is a result of the effects of ram pressure and thermal conduction in the intracluster medium (ICM). At the density and temperature of the ICM, the mean free paths of ICM electrons are comparable to the sizes of galaxies, therefore electrons can efficiently transport heat that is due to thermal conduction from the hot ICM to the cooler ISM. Galaxies consisting of dark matter halos and hot gas coronae are embedded in an ICM-like “wind tunnel” in our simulations. In this paper, we assume that thermal conduction is isotropic and include the effects of saturation. We find that as heat is transferred from the ICM to the ISM, the cooler denser ISM expands and evaporates. This process is significantly faster than gas loss due to ram pressure stripping; for our standard model galaxy, the evaporation time is 160 Myr, while the ram pressure stripping timescale is 2.5 Gyr. Thermal conduction also suppresses the formation of shear instabilities, and there are no stripped ISM tails since the ISM evaporates before tails can form. Observations of long-lived X-ray emitting coronae and ram pressure stripped X-ray tails in galaxies in group and cluster environments therefore require that thermal conduction is suppressed or offset by some additional physical process. The most likely process is anisotropic thermal conduction that is due to magnetic fields in the ISM and ICM, which we simulate and study in the next paper in this series.

  4. The Evaporation and Survival of Cluster Galaxy Coronae. I. The Effectiveness of Isotropic Thermal Conduction Including Saturation

    International Nuclear Information System (INIS)

    Vijayaraghavan, Rukmani; Sarazin, Craig

    2017-01-01

    We simulate the evolution of cluster galaxy hot interstellar medium (ISM) gas that is a result of the effects of ram pressure and thermal conduction in the intracluster medium (ICM). At the density and temperature of the ICM, the mean free paths of ICM electrons are comparable to the sizes of galaxies, therefore electrons can efficiently transport heat that is due to thermal conduction from the hot ICM to the cooler ISM. Galaxies consisting of dark matter halos and hot gas coronae are embedded in an ICM-like “wind tunnel” in our simulations. In this paper, we assume that thermal conduction is isotropic and include the effects of saturation. We find that as heat is transferred from the ICM to the ISM, the cooler denser ISM expands and evaporates. This process is significantly faster than gas loss due to ram pressure stripping; for our standard model galaxy, the evaporation time is 160 Myr, while the ram pressure stripping timescale is 2.5 Gyr. Thermal conduction also suppresses the formation of shear instabilities, and there are no stripped ISM tails since the ISM evaporates before tails can form. Observations of long-lived X-ray emitting coronae and ram pressure stripped X-ray tails in galaxies in group and cluster environments therefore require that thermal conduction is suppressed or offset by some additional physical process. The most likely process is anisotropic thermal conduction that is due to magnetic fields in the ISM and ICM, which we simulate and study in the next paper in this series.

  5. Safeguards system effectiveness modeling

    International Nuclear Information System (INIS)

    Bennett, H.A.; Boozer, D.D.; Chapman, L.D.; Daniel, S.L.; Engi, D.; Hulme, B.L.; Varnado, G.B.

    1976-01-01

    A general methodology for the comparative evaluation of physical protection system effectiveness at nuclear facilities is presently under development. The approach is applicable to problems of sabotage or theft at fuel cycle facilities. The overall methodology and the primary analytic techniques used to assess system effectiveness are briefly outlined

  6. Safeguards system effectiveness modeling

    International Nuclear Information System (INIS)

    Bennett, H.A.; Boozer, D.D.; Chapman, L.D.; Daniel, S.L.; Engi, D.; Hulme, B.L.; Varnado, G.B.

    1976-01-01

    A general methodology for the comparative evaluation of physical protection system effectiveness at nuclear facilities is presently under development. The approach is applicable to problems of sabotage or theft at fuel cycle facilities. In this paper, the overall methodology and the primary analytic techniques used to assess system effectiveness are briefly outlined

  7. Expansion Hamiltonian model for a diatomic molecule adsorbed on a surface: Vibrational states of the CO/Cu(100) system including surface vibrations

    Energy Technology Data Exchange (ETDEWEB)

    Meng, Qingyong, E-mail: mengqingyong@dicp.ac.cn [State Key Laboratory of Molecular Reaction Dynamics, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Zhongshan Road 457, 116023 Dalian (China); Meyer, Hans-Dieter, E-mail: hans-dieter.meyer@pci.uni-heidelberg.de [Theoretische Chemie, Physikalisch-Chemisches Institut, Ruprecht-Karls Universität Heidelberg, Im Neuenheimer Feld 229, D-69120 Heidelberg (Germany)

    2015-10-28

    Molecular-surface studies are often done by assuming a corrugated, static (i.e., rigid) surface. To be able to investigate the effects that vibrations of surface atoms may have on spectra and cross sections, an expansion Hamiltonian model is proposed on the basis of the recently reported [R. Marquardt et al., J. Chem. Phys. 132, 074108 (2010)] SAP potential energy surface (PES), which was built for the CO/Cu(100) system with a rigid surface. In contrast to other molecule-surface coupling models, such as the modified surface oscillator model, the coupling between the adsorbed molecule and the surface atoms is already included in the present expansion SAP-PES model, in which a Taylor expansion around the equilibrium positions of the surface atoms is performed. To test the quality of the Taylor expansion, a direct model, that is avoiding the expansion, is also studied. The latter, however, requests that there is only one movable surface atom included. On the basis of the present expansion and direct models, the effects of a moving top copper atom (the one to which CO is bound) on the energy levels of a bound CO/Cu(100) system are studied. For this purpose, the multiconfiguration time-dependent Hartree calculations are carried out to obtain the vibrational fundamentals and overtones of the CO/Cu(100) system including a movable top copper atom. In order to interpret the results, a simple model consisting of two coupled harmonic oscillators is introduced. From these calculations, the vibrational levels of the CO/Cu(100) system as function of the frequency of the top copper atom are discussed.

  8. Comprehensive capacitance-voltage analysis including quantum effects for high-k interfaces on germanium and other alternative channel materials

    Science.gov (United States)

    Anwar, Sarkar R. M.

    High mobility alternative channel materials to silicon are critical to the continued scaling of metal oxide semiconductor (MOS) devices. However, before they can be incorporated into advanced devices, some major issues need to be solved. The high mobility materials suffer from lower allowable thermal budgets compared to Si (before desorption and defect formation becomes an issue) and the absence of a good quality native oxide has further increased the interest in the use of high-k dielectrics. However, the high interface state density and high electric fields at these semiconductor/high-k interfaces can significantly impact the capacitance-voltage (C-V) profile, and current C-V modeling software cannot account for these effects. This in turn affects the parameters extracted from the C-V data of the high mobility semiconductor/high-k interface, which are crucial to fully understand the interface properties and expedite process development. To address this issue, we developed a model which takes into account quantum corrections which can be applied to a number of these alternative channel materials including SixGe1-x, Ge, InGaAs, and GaAs. The C-V simulation using this QM correction model is orders of magnitude faster compared to a full band Schrodinger-Poisson solver. The simulated C-V is directly benchmarked to a self consistent Schrodinger-Poisson solution for each bulk semiconductor material, and from the benchmarking process the QM correction parameters are extracted. The full program, C-V Alternative Channel Extraction (CV ACE), incorporates a quantum mechanical correction model, along with the interface state density model, and can extract device parameters such as equivalent oxide thickness (EOT), doping density and flat band voltage (Vfb) as well as the interface state density profile using multiple measurements performed at different frequencies and temperatures, simultaneously. The program was used to analyze experimentally measured C-V profiles and the

  9. A Self-consistent Model of the Coronal Heating and Solar Wind Acceleration Including Compressible and Incompressible Heating Processes

    Science.gov (United States)

    Shoda, Munehito; Yokoyama, Takaaki; Suzuki, Takeru K.

    2018-02-01

    We propose a novel one-dimensional model that includes both shock and turbulence heating and qualify how these processes contribute to heating the corona and driving the solar wind. Compressible MHD simulations allow us to automatically consider shock formation and dissipation, while turbulent dissipation is modeled via a one-point closure based on Alfvén wave turbulence. Numerical simulations were conducted with different photospheric perpendicular correlation lengths {λ }0, which is a critical parameter of Alfvén wave turbulence, and different root-mean-square photospheric transverse-wave amplitudes δ {v}0. For the various {λ }0, we obtain a low-temperature chromosphere, high-temperature corona, and supersonic solar wind. Our analysis shows that turbulence heating is always dominant when {λ }0≲ 1 {Mm}. This result does not mean that we can ignore the compressibility because the analysis indicates that the compressible waves and their associated density fluctuations enhance the Alfvén wave reflection and therefore the turbulence heating. The density fluctuation and the cross-helicity are strongly affected by {λ }0, while the coronal temperature and mass-loss rate depend weakly on {λ }0.

  10. Hydraulic Model for Drinking Water Networks, Including Household Connections; Modelo hidraulico para redes de agua potable con tomas domiciliarias

    Energy Technology Data Exchange (ETDEWEB)

    Guerrero Angulo, Jose Oscar [Universidad Autonoma de Sinaloa (Mexico); Arreguin Cortes, Felipe [Instituto Mexicano de Tecnologia del Agua, Jiutepec, Morelos (Mexico)

    2002-03-01

    This paper presents a hydraulic simulation model for drinking water networks, including elements that are currently not considered household connections, spatially variable flowrate distribution pipelines, and tee secondary network. This model is determined by solving the equations needed for a conventional model following an indirect procedure for the solution of large equations systems. Household connection performance is considered as dependent of water pressure and the way in which users operate the taps of such intakes. This approach allows a better a acquaintance with the drinking water supply networks performance as well as solving problems that demand a more precise hydraulic simulation, such as water quality variations, leaks in networks, and the influence of home water tanks as regulating devices. [Spanish] Se presenta un modelo de simulacion hidraulica para redes de agua potable en el cual se incluyen elementos que no se toman en cuenta actualmente, como las tomas domiciliarias, los tubos de distribucion con gastos espacialmente variado y la red secundaria, resolviendo el numero de ecuaciones que seria necesario plantear en un modelo convencional mediante un procedimiento indirecto para la solucion de grandes sistemas de ecuaciones. En las tomas domiciliarias se considera que su funcionamiento depende de las presiones y la forma en que los usuarios operan las llaves de las mismas. Este planteamiento permite conocer mejor el funcionamiento de las redes de abastecimiento de agua potable y solucionar problemas que requieren de una simulacion hidraulica mas precisa, como el comportamiento de la calidad del agua, las fugas en las redes y la influencia reguladora de los tinacos de las casas.

  11. Anisotropic damage model for concrete including unilateral effects: application to numerical simulation of confinement vessels; Modelisation de l'endommagement anisotrope du beton avec prise en compte de l'effet unilateral: application a la simulation des enceintes de confinement nucleaires

    Energy Technology Data Exchange (ETDEWEB)

    Godard, V

    2005-01-15

    The behaviour of concrete, considered as isotropic for a sound material, becomes anisotropic and unilateral as soon as microcracks are initiated. Concrete also shows a different behaviour in tension than in compression. However, isotropic models, which are more simple and time costless, are still widely used for industrial applications. An anisotropic and unilateral model, with few parameters, is thus proposed in the present work, which enhances the accuracy of the description of concrete's behaviour, while remaining suitable for industrial studies. The validation of the model is based on experimental results. Numerical simulations of structures are also proposed, among which one concerns a representative volume of a confinement vessel. Finally, a non local theory is investigated to overcome the problems induced by strain localisation. (author)

  12. Dynamic experiments with high bisphenol-A concentrations modelled with an ASM model extended to include a separate XOC degrading microorganism

    DEFF Research Database (Denmark)

    Lindblom, Erik Ulfson; Press-Kristensen, Kåre; Vanrolleghem, P.A.

    2009-01-01

    with the endocrine disrupting XOC bisphenol-A (BPA) in an activated sludge process with real wastewater were used to hypothesize an ASM-based process model including aerobic growth of a specific BPA-degrading microorganism and sorption of BPA to sludge. A parameter estimation method was developed, which...

  13. Modelling the residual stresses and microstructural evolution in Friction Stir Welding of AA2024-T3 including the Wagner-Kampmann precipitation model

    DEFF Research Database (Denmark)

    Sonne, Mads Rostgaard; Hattel, Jesper Henri

    In this work, a numerical finite element model for friction stir welding of 2024-T3 aluminum alloy, consisting of a heat transfer analysis and a sequentially coupled quasi-static stress analysis is proposed. Metallurgical softening of the material is properly considered and included...

  14. Design and modeling of an advanced marine machinery system including waste heat recovery and removal of sulphur oxides

    DEFF Research Database (Denmark)

    Frimann Nielsen, Rasmus; Haglind, Fredrik; Larsen, Ulrik

    2013-01-01

    of the machinery system. The wet sulphuric acid process has shown to be an effective way of removing sulphur oxides from flue gas of land-based coal fired power plants. Moreover, organic Rankine cycles are suitable for heat to power conversion for low temperature heat sources. This paper is aimed at designing...... consists of a two-stroke diesel engine, the wet sulphuric process for sulphur removal and an advanced waste heat recovery system including a conventional steam Rankine cycle and an organic Rankine cycle. The results are compared with those of a state-of-the-art machinery system featuring a two......-stroke diesel engine and a conventional waste heat recovery system. The results suggest that an organic Rankine cycle placed after the conventional waste heat recovery system is able to extract the sulphuric acid from the exhaust gas, while at the same time increase power generation from waste heat by 32...

  15. Effects of Leisure Education Programme Including Sportive Activities on Perceived Freedom in Leisure of Adolescents with Intellectual Disabilities

    Science.gov (United States)

    Ertuzun, Ezgi

    2015-01-01

    The objective of this experimental study is to determine the effect of leisure education programme including sportive activities on the perceived freedom in leisure of adolescents with mild intellectual disabilities. The research was designed with an experimental group (n = 37) and a control group (n = 34), and was conducted among a total of 71…

  16. INCLUDING RISK IN ECONOMIC FEASIBILITY ANALYSIS:A STOCHASTIC SIMULATION MODEL FOR BLUEBERRY INVESTMENT DECISIONS IN CHILE

    Directory of Open Access Journals (Sweden)

    GERMÁN LOBOS

    2015-12-01

    Full Text Available ABSTRACT The traditional method of net present value (NPV to analyze the economic profitability of an investment (based on a deterministic approach does not adequately represent the implicit risk associated with different but correlated input variables. Using a stochastic simulation approach for evaluating the profitability of blueberry (Vaccinium corymbosum L. production in Chile, the objective of this study is to illustrate the complexity of including risk in economic feasibility analysis when the project is subject to several but correlated risks. The results of the simulation analysis suggest that the non-inclusion of the intratemporal correlation between input variables underestimate the risk associated with investment decisions. The methodological contribution of this study illustrates the complexity of the interrelationships between uncertain variables and their impact on the convenience of carrying out this type of business in Chile. The steps for the analysis of economic viability were: First, adjusted probability distributions for stochastic input variables (SIV were simulated and validated. Second, the random values of SIV were used to calculate random values of variables such as production, revenues, costs, depreciation, taxes and net cash flows. Third, the complete stochastic model was simulated with 10,000 iterations using random values for SIV. This result gave information to estimate the probability distributions of the stochastic output variables (SOV such as the net present value, internal rate of return, value at risk, average cost of production, contribution margin and return on capital. Fourth, the complete stochastic model simulation results were used to analyze alternative scenarios and provide the results to decision makers in the form of probabilities, probability distributions, and for the SOV probabilistic forecasts. The main conclusion shown that this project is a profitable alternative investment in fruit trees in

  17. Thomas Kuhn's 'Structure of Scientific Revolutions' applied to exercise science paradigm shifts: example including the Central Governor Model.

    Science.gov (United States)

    Pires, Flávio de Oliveira; de Oliveira Pires, Flávio

    2013-07-01

    According to Thomas Kuhn, the scientific progress of any discipline could be distinguished by a pre-paradigm phase, a normal science phase and a revolution phase. The science advances when a scientific revolution takes place after silent period of normal science and the scientific community moves ahead to a paradigm shift. I suggest there has been a recent change of course in the direction of the exercise science. According to the 'current paradigm', exercise would be probably limited by alterations in either central command or peripheral skeletal muscles, and fatigue would be developed in a task-dependent manner. Instead, the central governor model (GCM) has proposed that all forms of exercise are centrally-regulated, the central nervous system would calculate the metabolic cost required to complete a task in order to avoid catastrophic body failure. Some have criticized the CGM and supported the traditional interpretation, but recently the scientific community appears to have begun an intellectual trajectory to accept this theory. First, the increased number of citations of articles that have supported the CGM could indicate that the community has changed the focus. Second, relevant journals have devoted special editions to promote the debate on subjects challenged by the CGM. Finally, scientists from different fields have recognized mechanisms included in the CGM to understand the exercise limits. Given the importance of the scientific community in demarcating a Kuhnian paradigm shift, I suggest that these three aspects could indicate an increased acceptance of a centrally-regulated effort model, to understand the limits of exercise.

  18. Model of spur processes in aqueous radiation chemistry including spur overlap and a novel initial hydrated electron distribution

    International Nuclear Information System (INIS)

    Short, D.R.

    1980-01-01

    Results are presented from computer calculations based upon an improved diffusion-kinetic model of the spur which includes a novel initial distribution for the hydrated electron and an approximate mathematical treatment of the overlap of spurs in three dimensions. Experimental data for the decay of the hydrated electron and hydroxyl radical before one in electron-pulse-irradated, solute-free and air-free water are fit wihtin experimental uncertainty by adjustment of the initial spatial distributions of spur intermediates and the average energy deposited in the spur. Using the same values of these parameters, the hydrated electron decay is computed for times from 1 ps 10 μs after the radiatio pulse. The results of such calcuations for various conditions of pulse dose and concentrations of scavengers of individual primary chemical species in the spur are compared with corresponding experimental data obtained predominantly from water and aqueous solutions irradiated with 10 to 15 MeV electron pulses. Very good agreement between calculated and experimental hydrated electron decay in pure water is observed for the entire time range studied when a pulse dose of approximately 7900 rads is modeled, but the calcuated and experimental curves are observed to deviate for times greater than 10 ns nanoseconds when low pulse doses and low scavenger concentrations are considered. It is shown that this deviation is experimental and calculated hydrated electron decay cannot be explained by assuming the presence of a hydrated electron scavenging impurity nor by employing a distribution of nearest neighbor interspur distances to refine the overlap approximation

  19. The clinical obesity maintenance model: an integration of psychological constructs including mood, emotional regulation, disordered overeating, habitual cluster behaviours, health literacy and cognitive function.

    Science.gov (United States)

    Raman, Jayanthi; Smith, Evelyn; Hay, Phillipa

    2013-01-01

    Psychological distress and deficits in executive functioning are likely to be important barriers to effective weight loss maintenance. The purpose of this paper is twofold. First, in the light of recent evidence in the fields of neuropsychology and obesity, particularly on the deficits in the executive function in overweight and obese individuals, a conceptual and theoretical framework of obesity maintenance is introduced by way of a clinical obesity maintenance model (COMM). It is argued that psychological variables, that of habitual cluster Behaviors, emotional dysregulation, mood, and health literacy, interact with executive functioning and impact on the overeating/binge eating behaviors of obese individuals. Second, cognizant of this model, it is argued that the focus of obesity management should be extended to include a broader range of maintaining mechanisms, including but not limited to cognitive deficits. Finally, a discussion on potential future directions in research and practice using the COMM is provided.

  20. The Clinical Obesity Maintenance Model: An Integration of Psychological Constructs including Mood, Emotional Regulation, Disordered Overeating, Habitual Cluster Behaviours, Health Literacy and Cognitive Function

    Directory of Open Access Journals (Sweden)

    Jayanthi Raman

    2013-01-01

    Full Text Available Psychological distress and deficits in executive functioning are likely to be important barriers to effective weight loss maintenance. The purpose of this paper is twofold. First, in the light of recent evidence in the fields of neuropsychology and obesity, particularly on the deficits in the executive function in overweight and obese individuals, a conceptual and theoretical framework of obesity maintenance is introduced by way of a clinical obesity maintenance model (COMM. It is argued that psychological variables, that of habitual cluster Behaviors, emotional dysregulation, mood, and health literacy, interact with executive functioning and impact on the overeating/binge eating behaviors of obese individuals. Second, cognizant of this model, it is argued that the focus of obesity management should be extended to include a broader range of maintaining mechanisms, including but not limited to cognitive deficits. Finally, a discussion on potential future directions in research and practice using the COMM is provided.

  1. Quantifying the Earthquake Clustering that Independent Sources with Stationary Rates (as Included in Current Risk Models) Can Produce.

    Science.gov (United States)

    Fitzenz, D. D.; Nyst, M.; Apel, E. V.; Muir-Wood, R.

    2014-12-01

    The recent Canterbury earthquake sequence (CES) renewed public and academic awareness concerning the clustered nature of seismicity. Multiple event occurrence in short time and space intervals is reminiscent of aftershock sequences, but aftershock is a statistical definition, not a label one can give an earthquake in real-time. Aftershocks are defined collectively as what creates the Omori event rate decay after a large event or are defined as what is taken away as "dependent events" using a declustering method. It is noteworthy that depending on the declustering method used on the Canterbury earthquake sequence, the number of independent events varies a lot. This lack of unambiguous definition of aftershocks leads to the need to investigate the amount of clustering inherent in "declustered" risk models. This is the task we concentrate on in this contribution. We start from a background source model for the Canterbury region, in which 1) centroids of events of given magnitude are distributed using a latin-hypercube lattice, 2) following the range of preferential orientations determined from stress maps and focal mechanism, 3) with length determined using the local scaling relationship and 4) rates from a and b values derived from the declustered pre-2010 catalog. We then proceed to create tens of thousands of realizations of 6 to 20 year periods, and we define criteria to identify which successions of events in the region would be perceived as a sequence. Note that the spatial clustering expected is a lower end compared to a fully uniform distribution of events. Then we perform the same exercise with rates and b-values determined from the catalog including the CES. If the pre-2010 catalog was long (or rich) enough, then the computed "stationary" rates calculated from it would include the CES declustered events (by construction, regardless of the physical meaning of or relationship between those events). In regions of low seismicity rate (e.g., Canterbury before

  2. Effective modelling of acoustofluidic devices

    DEFF Research Database (Denmark)

    Ley, Mikkel Wennemoes Hvitfeld

    , and 3) acoustic streaming patterns in the devices considered in model 2). 1) We derive an effective model for numerical studies of hydrodynamic particle-particle interactions in microfluidic high-concentration suspensions. A suspension of microparticles placed in a microfluidic channel and influenced...... and travelling waves as well as absorption. We model the connective tubing at the outlets, either as being free reflecting surfaces or perfect absorbers of outgoing acoustic waves, and we make an effective description of the mechanical actuation of the attached piezoelectric transducer. 3) Using the model...

  3. Development of a fluidized bed agglomeration modeling methodology to include particle-level heterogeneities in ash chemistry and granular physics

    Science.gov (United States)

    Khadilkar, Aditi B.

    The utility of fluidized bed reactors for combustion and gasification can be enhanced if operational issues such as agglomeration are mitigated. The monetary and efficiency losses could be avoided through a mechanistic understanding of the agglomeration process and prediction of operational conditions that promote agglomeration. Pilot-scale experimentation prior to operation for each specific condition can be cumbersome and expensive. So the development of a mathematical model would aid predictions. With this motivation, the study comprised of the following model development stages- 1) development of an agglomeration modeling methodology based on binary particle collisions, 2) study of heterogeneities in ash chemical composition and gaseous atmosphere, 3) computation of a distribution of particle collision frequencies based on granular physics for a poly-disperse particle size distribution, 4) combining the ash chemistry and granular physics inputs to obtain agglomerate growth probabilities and 5) validation of the modeling methodology. The modeling methodology comprised of testing every binary particle collision in the system for sticking, based on the extent of dissipation of the particles' kinetic energy through viscous dissipation by slag-liquid (molten ash) covering the particles. In the modeling methodology developed in this study, thermodynamic equilibrium calculations are used to estimate the amount of slag-liquid in the system, and the changes in particle collision frequencies are accounted for by continuously tracking the number density of the various particle sizes. In this study, the heterogeneities in chemical composition of fuel ash were studied by separating the bulk fuel into particle classes that are rich in specific minerals. FactSage simulations were performed on two bituminous coals and an anthracite to understand the effect of particle-level heterogeneities on agglomeration. The mineral matter behavior of these constituent classes was studied

  4. Numerical modeling and experimental validation of the acoustic transmission of aircraft's double-wall structures including sound package

    Science.gov (United States)

    Rhazi, Dilal

    In the field of aeronautics, reducing the harmful effects of acoustics constitutes a major concern at the international level and justifies the call for further research, particularly in Canada where aeronautics is a key economic sector, which operates in a context of global competition. Aircraft sidewall structure is usually of a double wall construction with a curved ribbed metallic skin and a lightweight composite or sandwich trim separated by a cavity filled with a noise control treatment. The latter is of a great importance in the transport industry, and continues to be of interest in many engineering applications. However, the insertion loss noise control treatment depends on the excitation of the supporting structure. In particular, Turbulent Boundary Layer is of interest to several industries. This excitation is difficult to simulate in laboratory conditions, given the prohibiting costs and difficulties associated with wind tunnel and in-flight tests. Numerical simulation is the only practical way to predict the response to such excitations and to analyze effects of design changes to the response to such excitation. Another kinds of excitations encountered in industrial are monopole, rain on the Roof and diffuse acoustic field. Deterministic methods can calculate in each point the spectral response of the system. Most known are numerical methods such as finite elements and boundary elements methods. These methods generally apply to the low frequency where modal behavior of the structure dominates. However, the high limit of calculation in frequency of these methods cannot be defined in a strict way because it is related to the capacity of data processing and to the nature of the studied mechanical system. With these challenges in mind, and with limitations of the main numerical codes on the market, the manufacturers have expressed the need for simple models immediately available as early as the stage of preliminary drafts. This thesis represents an attempt

  5. Laurentian Great Lakes Phytoplankton and Their Water Quality Characteristics, Including a Diatom-Based Model for Paleoreconstruction of Phosphorus

    Science.gov (United States)

    Reavie, Euan D.; Heathcote, Adam J.; Shaw Chraïbi, Victoria L.

    2014-01-01

    Recent shifts in water quality and food web characteristics driven by anthropogenic impacts on the Laurentian Great Lakes warranted an examination of pelagic primary producers as tracers of environmental change. The distributions of the 263 common phytoplankton taxa were related to water quality variables to determine taxon-specific responses that may be useful in indicator models. A detailed checklist of taxa and their environmental optima are provided. Multivariate analyses indicated a strong relationship between total phosphorus (TP) and patterns in the diatom assemblages across the Great Lakes. Of the 118 common diatom taxa, 90 (76%) had a directional response along the TP gradient. We further evaluated a diatom-based transfer function for TP based on the weighted-average abundance of taxa, assuming unimodal distributions along the TP gradient. The r2 between observed and inferred TP in the training dataset was 0.79. Substantial spatial and environmental autocorrelation within the training set of samples justified the need for further model validation. A randomization procedure indicated that the actual transfer function consistently performed better than functions based on reshuffled environmental data. Further, TP was minimally confounded by other environmental variables, as indicated by the relatively large amount of unique variance in the diatoms explained by TP. We demonstrated the effectiveness of the transfer function by hindcasting TP concentrations using fossil diatom assemblages in a Lake Superior sediment core. Passive, multivariate analysis of the fossil samples against the training set indicated that phosphorus was a strong determinant of historical diatom assemblages, verifying that the transfer function was suited to reconstruct past TP in Lake Superior. Collectively, these results showed that phytoplankton coefficients for water quality can be robust indicators of Great Lakes pelagic condition. The diatom-based transfer function can be used in

  6. Analysis of quantum ballistic electron transport in ultrasmall silicon devices including space-charge and geometric effects

    Science.gov (United States)

    Laux, S. E.; Kumar, A.; Fischetti, M. V.

    2004-05-01

    A two-dimensional device simulation program which self consistently solves the Schrödinger and Poisson equations with current flow is described in detail. Significant approximations adopted in this work are the absence of scattering and a simple six-valley, parabolic band structure for silicon. A modified version of the quantum transmitting boundary method is used to describe open boundary conditions permitting current flow in device solutions far from equilibrium. The continuous energy spectrum of the system is discretized by temporarily imposing two different forms of closed boundary conditions, resulting in energies which sample the density-of-states and establish the wave function normalization conditions. These standing wave solutions ("normal modes") are decomposed into their traveling wave constituents, each of which represents injection from only one of the open boundary contacts ("traveling eigencomponents"). These current-carrying states are occupied by a drifted Fermi distribution associated with their injecting contact and summed to form the electron density in the device. Holes are neglected in this calculation. The Poisson equation is solved on the same finite element computational mesh as the Schrödinger equation; devices of arbitrary geometry can be modeled. Computational performance of the program including characterization of a "Broyden+Newton" algorithm employed in the iteration for self consistency is described. Device results are presented for a narrow silicon resonant tunneling diode (RTD) and many variants of idealized silicon double-gate field effect transistors (DGFETs). The RTD results show two resonant conduction peaks, each of which demonstrates hysteresis. Three 7.5 nm channel length DGFET structures with identical intrinsic device configurations but differing access geometries (straight, taper and "dog bone") are studied and found to have differing current flows owing to quantum-mechanical reflection in their access regions

  7. Simulation of spatially varying ground motions including incoherence, wave‐passage and differential site‐response effects

    DEFF Research Database (Denmark)

    Konakli, Katerina; Der Kiureghian, Armen

    2012-01-01

    A method is presented for simulating arrays of spatially varying ground motions, incorporating the effects of incoherence, wave passage, and differential site response. Non‐stationarity is accounted for by considering the motions as consisting of stationary segments. Two approaches are developed...... of multiply‐supported structures. In the second approach, simulated motions are conditioned on the segmented record itself and exhibit increasing variance with distance from the site of the observation. For both approaches, example simulated motions are presented for an existing bridge model employing two...... alternatives for modeling the local soil response: i) idealizing each soil‐column as a single‐degree‐of‐freedom oscillator, and ii) employing the theory of vertical wave propagation in a single soil layer over bedrock. The selection of parameters in the simulation procedure and their effects...

  8. Automatic Parameter Extraction Technique for MOS Structures by C-V Characterization Including the Effects of Interface States

    Science.gov (United States)

    Ryazantsev, D. V.; Grudtsov, V. P.

    2016-10-01

    An automatic MOS structure parameter extraction algorithm accounting for quantum effects has been developed and applied in the semiconductor device analyzer Agilent B1500A. Parameter extraction is based on matching the experimental C-V data with numerical modeling results. The algorithm is used to extract the parameters of test MOS structures with ultrathin gate dielectrics. The applicability of the algorithm for the determination of distribution function of DOS and finding the donor defect level in silicon is shown.

  9. Automatic Parameter Extraction Technique for MOS Structures by C-V Characterization Including the Effects of Interface States

    Directory of Open Access Journals (Sweden)

    Ryazantsev D. V.

    2016-10-01

    Full Text Available An automatic MOS structure parameter extraction algorithm accounting for quantum effects has been developed and applied in the semiconductor device analyzer Agilent B1500A. Parameter extraction is based on matching the experimental C-V data with numerical modeling results. The algorithm is used to extract the parameters of test MOS structures with ultrathin gate dielectrics. The applicability of the algorithm for the determination of distribution function of DOS and finding the donor defect level in silicon is shown.

  10. Modelling the long-term consequences of a hypothetical dispersal of radioactivity in an urban area including remediation alternatives

    DEFF Research Database (Denmark)

    Thiessen, K.M.; Andersson, Kasper Grann; Batandjieva, B.

    2009-01-01

    The Urban Remediation Working Group of the International Atomic Energy Agency's EMRAS (Environmental Modelling for Radiation Safety) program was organized to address issues of remediation assessment modelling for urban areas contaminated with dispersed radionuclides. The present paper describes t...

  11. The importance of including dynamic social networks when modeling epidemics of airborne infections: does increasing complexity increase accuracy?

    OpenAIRE

    Blower, Sally; Go, Myong-Hyun

    2011-01-01

    Abstract Mathematical models are useful tools for understanding and predicting epidemics. A recent innovative modeling study by Stehle and colleagues addressed the issue of how complex models need to be to ensure accuracy. The authors collected data on face-to-face contacts during a two-day conference. They then constructed a series of dynamic social contact networks, each of which was used to model an epidemic generated by a fast-spreading airborne pathogen. Intriguingly, Stehle and colleagu...

  12. Assessment of commercially available energy-efficient room air conditioners including models with low global warming potential (GWP) refrigerants

    Energy Technology Data Exchange (ETDEWEB)

    Shah, N. K. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Park, W. Y. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Gerke, B. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2017-08-30

    , the highest-efficiency RAC models employ the low-GWP refrigerants R-32 or R-290. • RACs are available in most regions and worldwide that surpass the highest efficiency levels recognized by labeling programs. • Fixed-speed RACs using high-GWP and ozone-depleting R-22 refrigerant still dominate the market in many emerging economies. There is significant scope to improve RAC efficiency and transition to low-GWP refrigerants using commercially available technology and to design market-transformation programs for high-efficiency, low-GWP equipment including standards, labeling, procurement, and incentive programs.

  13. Convex reformulation of biologically-based multi-criteria intensity-modulated radiation therapy optimization including fractionation effects.

    Science.gov (United States)

    Hoffmann, Aswin L; den Hertog, Dick; Siem, Alex Y D; Kaanders, Johannes H A M; Huizenga, Henk

    2008-11-21

    Finding fluence maps for intensity-modulated radiation therapy (IMRT) can be formulated as a multi-criteria optimization problem for which Pareto optimal treatment plans exist. To account for the dose-per-fraction effect of fractionated IMRT, it is desirable to exploit radiobiological treatment plan evaluation criteria based on the linear-quadratic (LQ) cell survival model as a means to balance the radiation benefits and risks in terms of biologic response. Unfortunately, the LQ-model-based radiobiological criteria are nonconvex functions, which make the optimization problem hard to solve. We apply the framework proposed by Romeijn et al (2004 Phys. Med. Biol. 49 1991-2013) to find transformations of LQ-model-based radiobiological functions and establish conditions under which transformed functions result in equivalent convex criteria that do not change the set of Pareto optimal treatment plans. The functions analysed are: the LQ-Poisson-based model for tumour control probability (TCP) with and without inter-patient heterogeneity in radiation sensitivity, the LQ-Poisson-based relative seriality s-model for normal tissue complication probability (NTCP), the equivalent uniform dose (EUD) under the LQ-Poisson model and the fractionation-corrected Probit-based model for NTCP according to Lyman, Kutcher and Burman. These functions differ from those analysed before in that they cannot be decomposed into elementary EUD or generalized-EUD functions. In addition, we show that applying increasing and concave transformations to the convexified functions is beneficial for the piecewise approximation of the Pareto efficient frontier.

  14. Multibody Dynamics of a Fluid Power Radial Piston Motor Including Transient Hydrodynamic Pressure Models of Lubricating Gaps

    DEFF Research Database (Denmark)

    Johansen, Per; Rømer, Daniel; Andersen, Torben Ole

    2014-01-01

    The increasing interest in hydraulic transmissions in wind and wave energy applications has created an incentive for the development of high efficiency fluid power machinery. Modeling and analysis of fluid power machinery loss mechanisms are necessary in order to accommodate this demand. At present...... fully coupled thermo-elastic models has been used to simulate and study loss mechanisms in various tribological interfaces. Consequently, a reasonable focus of further development is to couple the interface models and the rigid body mechanics of fluid power machinery. The focus of the current paper...... is a multibody dynamics model of a radial piston fluid power motor, which connects the rigid bodies through models of the transient hydrodynamic lubrication pressure in the joint clearance. A finite volume approach is used to model the pressure dynamics of the fluid film lubrication. The model structure...

  15. The effect of coverings, including plastic bags and wraps, on mortality and morbidity in preterm and full-term neonates

    OpenAIRE

    Oatley, H K; Blencowe, H; Lawn, J E

    2016-01-01

    Neonatal hypothermia is an important risk factor for mortality and morbidity, and is common even in temperate climates. We conducted a systematic review to determine whether plastic coverings, used immediately following delivery, were effective in reducing the incidence of mortality, hypothermia and morbidity. A total of 26 studies (2271 preterm and 1003 term neonates) were included. Meta-analyses were conducted as appropriate. Plastic wraps were associated with a reduction in hypothermia in ...

  16. The effect on climate change impacts for building products when including the timing of greenhouse gas emissions

    Science.gov (United States)

    Richard D Bergman

    2012-01-01

    Greenhouse gases (GHGs) trap infrared radiation emitting from the Earth’s surface to generate the “greenhouse effect” thus keeping the planet warm. Many natural activities including rotting vegetation emit GHGs such as carbon dioxide to produce this natural affect. However, in the last 200 years or so, human activity has increased the atmospheric concentrations of GHGs...

  17. Dynamic experiments with high bisphenol-A concentrations modelled with an ASM model extended to include a separate XOC degrading microorganism.

    Science.gov (United States)

    Lindblom, Erik; Press-Kristensen, Kåre; Vanrolleghem, Peter A; Mikkelsen, Peter S; Henze, Mogens

    2009-07-01

    The perspective of this work is to develop a model, which can be used to better understand and optimize wastewater treatment plants that are able to remove xenobiotic organic compounds (XOCs) in combination with removal of traditional pollutants. Results from dynamic experiments conducted with the endocrine disrupting XOC bisphenol-A (BPA) in an activated sludge process with real wastewater were used to hypothesize an ASM-based process model including aerobic growth of a specific BPA-degrading microorganism and sorption of BPA to sludge. A parameter estimation method was developed, which simultaneously utilizes steady-state background concentrations and dynamic step response data, as well as conceptual simplifications of the plant configuration. Validation results show that biodegradation of BPA is sensitive to operational conditions before and during the experiment and that the proposed model structure is capable of capturing important characteristics of the observed BPA removal, thus increasing the potential for generalizing knowledge obtained from plant specific experiments.

  18. Models of low-mass helium white dwarfs including gravitational settling, thermal and chemical diffusion, and rotational mixing

    Science.gov (United States)

    Istrate, A. G.; Marchant, P.; Tauris, T. M.; Langer, N.; Stancliffe, R. J.; Grassitelli, L.

    2016-10-01

    A large number of extremely low-mass helium white dwarfs (ELM WDs) have been discovered in recent years. The majority of them are found in close binary systems suggesting they are formed either through a common-envelope phase or via stable mass transfer in a low-mass X-ray binary (LMXB) or a cataclysmic variable (CV) system. Here, we investigate the formation of these objects through the LMXB channel with emphasis on the proto-WD evolution in environments with different metallicities. We study for the first time the combined effects of rotational mixing and element diffusion (e.g. gravitational settling, thermal and chemical diffusion) on the evolution of proto-WDs and on the cooling properties of the resulting WDs. We present state-of-the-art binary stellar evolution models computed with MESA for metallicities of Z = 0.02, 0.01, 0.001 and 0.0002, producing WDs with masses between 0.16-0.45 M⊙. Our results confirm that element diffusion plays a significant role in the evolution of proto-WDs that experience hydrogen shell flashes. The occurrence of these flashes produces a clear dichotomy in the cooling timescales of ELM WDs, which has important consequences e.g. for the age determination of binary millisecond pulsars. In addition, we confirm that the threshold mass at which this dichotomy occurs depends on metallicity. Rotational mixing is found to counteract the effect of gravitational settling in the surface layers of young, bloated ELM proto-WDs and therefore plays a key role in determining their surface chemical abundances, I.e. the observed presence of metals in their atmospheres. We predict that these proto-WDs have helium-rich envelopes through a significant part of their lifetime. This is of great importance as helium is a crucial ingredient in the driving of the κ-mechanism suggested for the newly observed ELM proto-WD pulsators. However, we find that the number of hydrogen shell flashes and, as a result, the hydrogen envelope mass at the beginning of

  19. The consequences of including non-additive effects on the genetic evaluation of harvest body weight in Coho salmon (Oncorhynchus kisutch

    Directory of Open Access Journals (Sweden)

    Neira Roberto

    2010-06-01

    Full Text Available Abstract Background In this study, we used different animal models to estimate genetic and environmental variance components on harvest weight in two populations of Oncorhynchus kisutch, forming two classes i.e. odd- and even-year spawners. Methods The models used were: additive, with and without inbreeding as a covariable (A + F and A respectively; additive plus common environmental due to full-sib families and inbreeding (A + C + F; additive plus parental dominance and inbreeding (A + D + F; and a full model (A + C + D + F. Genetic parameters and breeding values obtained by different models were compared to evaluate the consequences of including non-additive effects on genetic evaluation. Results Including inbreeding as a covariable did not affect the estimation of genetic parameters, but heritability was reduced when dominance or common environmental effects were included. A high heritability for harvest weight was estimated in both populations (even = 0.46 and odd = 0.50 when simple additive models (A + F and A were used. Heritabilities decreased to 0.21 (even and 0.37 (odd when the full model was used (A + C + D + F. In this full model, the magnitude of the dominance variance was 0.19 (even and 0.06 (odd, while the magnitude of the common environmental effect was lower than 0.01 in both populations. The correlation between breeding values estimated with different models was very high in all cases (i.e. higher than 0.98. However, ranking of the 30 best males and the 100 best females per generation changed when a high dominance variance was estimated, as was the case in one of the two populations (even. Conclusions Dominance and common environmental variance may be important components of variance in harvest weight in O. kisutch, thus not including them may produce an overestimation of the predicted response; furthermore, genetic evaluation was seen to be partially affected, since the ranking of selected animals changed with the inclusion of

  20. Estimation of hull girder vertical bending moments including non-linear and flexibility effects using closed form expressions

    DEFF Research Database (Denmark)

    Pedersen, Preben Terndrup; Jensen, Jørgen Juncher

    2009-01-01

    -induced loads are evaluated for specific operational profiles. Non-linearity in the wave bending moment is modeled using results derived from a second-order strip theory and water entry solutions for wedge type sections. Hence, bow flare slamming is accounted for through a momentum type of approach....... The stochastic properties of this non-linear response are calculated through a monotonic Hermite transformation. In addition, the impulse loading due to e.g. bottom slamming or a rapid change in bow flare is included using a modal expansion in the two lowest vertical vibration modes. These whipping vibrations...

  1. Modeling, Simulation, and Control of a Solar Electric Propulsion Vehicle in Near-Earth Vicinity Including Solar Array Degradation

    Science.gov (United States)

    Witzberger, Kevin (Inventor); Hojnicki, Jeffery (Inventor); Manzella, David (Inventor)

    2016-01-01

    Modeling and control software that integrates the complexities of solar array models, a space environment, and an electric propulsion system into a rigid body vehicle simulation and control model is provided. A rigid body vehicle simulation of a solar electric propulsion (SEP) vehicle may be created using at least one solar array model, at least one model of a space environment, and at least one model of a SEP propulsion system. Power availability and thrust profiles may be determined based on the rigid body vehicle simulation as the SEP vehicle transitions from a low Earth orbit (LEO) to a higher orbit or trajectory. The power availability and thrust profiles may be displayed such that a user can use the displayed power availability and thrust profiles to determine design parameters for an SEP vehicle mission.

  2. Pattern dynamics and filamentation of femtosecond terawatt laser pulses in air including the higher-order Kerr effects.

    Science.gov (United States)

    Huang, T W; Zhou, C T; He, X T

    2013-05-01

    Plasma defocusing and higher-order Kerr effects on multiple filamentation and pattern formation of ultrashort laser pulse propagation in air are investigated. Linear analyses and numerical results show that these two saturable nonlinear effects can destroy the coherent evolution of the laser field, and small-scale spatial turbulent structures rapidly appear. For the two-dimensional case, numerical simulations show that blow-up-like solutions, spatial chaos, and pseudorecurrence can appear at higher laser intensities if only plasma defocusing is included. These complex patterns result from the stochastic evolution of the higher- or shorter-wavelength modes of the laser light spectrum. From the viewpoint of nonlinear dynamics, filamentation can be attributed to the modulational instability of these spatial incoherent localized structures. Furthermore, filament patterns associated with multiphoton ionization of the air molecules with and without higher-order Kerr effects are compared.

  3. A Mechanistic Model of Botrytis cinerea on Grapevines That Includes Weather, Vine Growth Stage, and the Main Infection Pathways

    Science.gov (United States)

    González-Domínguez, Elisa; Caffi, Tito; Ciliberti, Nicola; Rossi, Vittorio

    2015-01-01

    A mechanistic model for Botrytis cinerea on grapevine was developed. The model, which accounts for conidia production on various inoculum sources and for multiple infection pathways, considers two infection periods. During the first period (“inflorescences clearly visible” to “berries groat-sized”), the model calculates: i) infection severity on inflorescences and young clusters caused by conidia (SEV1). During the second period (“majority of berries touching” to “berries ripe for harvest”), the model calculates: ii) infection severity of ripening berries by conidia (SEV2); and iii) severity of berry-to-berry infection caused by mycelium (SEV3). The model was validated in 21 epidemics (vineyard × year combinations) between 2009 and 2014 in Italy and France. A discriminant function analysis (DFA) was used to: i) evaluate the ability of the model to predict mild, intermediate, and severe epidemics; and ii) assess how SEV1, SEV2, and SEV3 contribute to epidemics. The model correctly classified the severity of 17 of 21 epidemics. Results from DFA were also used to calculate the daily probabilities that an ongoing epidemic would be mild, intermediate, or severe. SEV1 was the most influential variable in discriminating between mild and intermediate epidemics, whereas SEV2 and SEV3 were relevant for discriminating between intermediate and severe epidemics. The model represents an improvement of previous B. cinerea models in viticulture and could be useful for making decisions about Botrytis bunch rot control. PMID:26457808

  4. Processes in healthcare teams that include nurse practitioners: what do patients and families perceive to be effective?

    Science.gov (United States)

    Kilpatrick, Kelley; Jabbour, Mira; Fortin, Chantal

    2016-03-01

    To explore patient and family perceptions of team effectiveness of teams those include nurse practitioners in acute and primary care. Nurse practitioners provide safe and effective care. Patients are satisfied with the care provided by nurse practitioners. Research examining patient and family perceptions of team effectiveness following the implementation of nurse practitioners in teams is lacking. A descriptive qualitative design was used. We used purposeful sampling to identify participants in four clinical specialties. We collected data from March 2014-January 2015 using semi-structured interviews and demographic questionnaires. Content analysis was used. Descriptive statistics were generated. Participants (n = 49) believed that the teams were more effective after the implementation of a nurse practitioner and this was important to them. They described processes that teams with nurse practitioners used to effectively provide care. These processes included improved communication, involvement in decision-making, cohesion, care coordination, problem-solving, and a focus on the needs of patients and families. Participants highlighted the importance of interpersonal team dynamics. A human approach, trust, being open to discussion, listening to patient and family concerns and respect were particularly valued by participants. Different processes emerged as priorities when data were examined by speciality. However, communication, trust and taking the time to provide care were the most important processes. The study provides new insights into the views of patients and families and micro-level processes in teams with nurse practitioners. The relative importance of each process varied according to the patient's health condition. Patients and providers identified similar team processes. Future research is needed to identify how team processes influence care outcomes. The findings can support patients, clinicians and decision-makers to determine the processes to focus on to

  5. An integrated mathematical model for chemical oxygen demand (COD) removal in moving bed biofilm reactors (MBBR) including predation and hydrolysis.

    Science.gov (United States)

    Revilla, Marta; Galán, Berta; Viguri, Javier R

    2016-07-01

    An integrated mathematical model is proposed for modelling a moving bed biofilm reactor (MBBR) for removal of chemical oxygen demand (COD) under aerobic conditions. The composite model combines the following: (i) a one-dimensional biofilm model, (ii) a bulk liquid model, and (iii) biological processes in the bulk liquid and biofilm considering the interactions among autotrophic, heterotrophic and predator microorganisms. Depending on the values for the soluble biodegradable COD loading rate (SCLR), the model takes into account a) the hydrolysis of slowly biodegradable compounds in the bulk liquid, and b) the growth of predator microorganisms in the bulk liquid and in the biofilm. The integration of the model and the SCLR allows a general description of the behaviour of COD removal by the MBBR under various conditions. The model is applied for two in-series MBBR wastewater plant from an integrated cellulose and viscose production and accurately describes the experimental concentrations of COD, total suspended solids (TSS), nitrogen and phosphorous obtained during 14 months working at different SCLRs and nutrient dosages. The representation of the microorganism group distribution in the biofilm and in the bulk liquid allow for verification of the presence of predator microorganisms in the second reactor under some operational conditions. Copyright © 2016 Elsevier Ltd. All rights reserved.

  6. Effects of surfactant mixtures, including Corexit 9527, on bacterial oxidation of acetate and alkanes in crude oil

    Energy Technology Data Exchange (ETDEWEB)

    Bruheim, P.; Bredholt, H.; Eimhjellen, K. [Norwegian Univ. of Science and Technology, Trondheim (Norway). Dept. of Biotechnology

    1999-04-01

    Mixtures of nonionic and anionic surfactants, including Corexit 9527, were tested to determine their effects on bacterial oxidation of acetate and alkanes in crude oil by cells pregrown on these substrates. Corexit 9527 inhibited oxidation of the alkanes in crude oil by Acinetobacter calcoaceticus ATCC 31012, while Span 80, a Corexit 9527 constituent, markedly increased the oil oxidation rate. Another Corexit 9257 constituent, the negatively charged dioctyl sulfosuccinate (AOT), strongly reduced the oxidation rate. The combination of Span 80 and AOT increased the rate, but not as much as Span 80 alone increased it, which tentatively explained the negative effect of Corexit 9527. The results of acetate uptake and oxidation experiments indicated that the nonionic surfactants interacted with the acetate uptake system while the anionic surfactant interacted with the oxidation system of the bacteria. The overall effect of Corexit 9527 on alkane oxidation by A. calcoaceticus ATCC 31012 thus seems to be the sum of the independent effects of the individual surfactants in the surfactant mixture. When Rhodococcus sp. strain 094 was used, the alkane oxidation rate decreased to almost zero in the presence of a mixture of Tergitol 15-S-7 and AOT even though the Tergitol 15-S-7 surfactant increased the alkane oxidation rate and AOT did not affect it. This indicated that there was synergism between the two surfactants rather than an additive effect like that observed for A. calcoaceticus ATCC 31012.

  7. Effects of Lactobacillus salivarius, Lactobacillus reuteri, and Pediococcus acidilactici on the nematode Caenorhabditis elegans include possible antitumor activity.

    Science.gov (United States)

    Fasseas, Michael K; Fasseas, Costas; Mountzouris, Konstantinos C; Syntichaki, Popi

    2013-03-01

    This study examined the effects of three lactic acid bacteria (LAB) strains on the nematode Caenorhabditis elegans. Lactobacillus salivarius, Lactobacillus reuteri, and Pediococcus acidilactici were found to inhibit the development and growth of the worm. Compared to Escherichia coli used as the control, L. reuteri and P. acidilactici reduced the lifespan of wild-type and short-lived daf-16 worms. On the contrary, L. salivarius extended the lifespan of daf-16 worms when used live, but reduced it as UV-killed bacteria. The three LAB induced the expression of genes involved in pathogen response and inhibited the growth of tumor-like germ cells, without affecting DAF16 localization or increasing corpse cells. Our results suggest the possible use of C. elegans as a model for studying the antitumor attributes of LAB. The negative effects of these LAB strains on the nematode also indicate their potential use against parasitic nematodes.

  8. Including irrigation in niche modelling of the invasive wasp Vespula germanica (Fabricius) improves model fit to predict potential for further spread.

    Science.gov (United States)

    de Villiers, Marelize; Kriticos, Darren J; Veldtman, Ruan

    2017-01-01

    The European wasp, Vespula germanica (Fabricius) (Hymenoptera: Vespidae), is of Palaearctic origin, being native to Europe, northern Africa and Asia, and introduced into North America, Chile, Argentina, Iceland, Ascension Island, South Africa, Australia and New Zealand. Due to its polyphagous nature and scavenging behaviour, V. germanica threatens agriculture and silviculture, and negatively affects biodiversity, while its aggressive nature and venomous sting pose a health risk to humans. In areas with warmer winters and longer summers, queens and workers can survive the winter months, leading to the build-up of large nests during the following season; thereby increasing the risk posed by this species. To prevent or prepare for such unwanted impacts it is important to know where the wasp may be able to establish, either through natural spread or through introduction as a result of human transport. Distribution data from Argentina and Australia, and seasonal phenology data from Argentina were used to determine the potential distribution of V. germanica using CLIMEX modelling. In contrast to previous models, the influence of irrigation on its distribution was also investigated. Under a natural rainfall scenario, the model showed similarities to previous models. When irrigation is applied, dry stress is alleviated, leading to larger areas modelled climatically suitable compared with previous models, which provided a better fit with the actual distribution of the species. The main areas at risk of invasion by V. germanica include western USA, Mexico, small areas in Central America and in the north-western region of South America, eastern Brazil, western Russia, north-western China, Japan, the Mediterranean coastal regions of North Africa, and parts of southern and eastern Africa.

  9. Including irrigation in niche modelling of the invasive wasp Vespula germanica (Fabricius improves model fit to predict potential for further spread.

    Directory of Open Access Journals (Sweden)

    Marelize de Villiers

    Full Text Available The European wasp, Vespula germanica (Fabricius (Hymenoptera: Vespidae, is of Palaearctic origin, being native to Europe, northern Africa and Asia, and introduced into North America, Chile, Argentina, Iceland, Ascension Island, South Africa, Australia and New Zealand. Due to its polyphagous nature and scavenging behaviour, V. germanica threatens agriculture and silviculture, and negatively affects biodiversity, while its aggressive nature and venomous sting pose a health risk to humans. In areas with warmer winters and longer summers, queens and workers can survive the winter months, leading to the build-up of large nests during the following season; thereby increasing the risk posed by this species. To prevent or prepare for such unwanted impacts it is important to know where the wasp may be able to establish, either through natural spread or through introduction as a result of human transport. Distribution data from Argentina and Australia, and seasonal phenology data from Argentina were used to determine the potential distribution of V. germanica using CLIMEX modelling. In contrast to previous models, the influence of irrigation on its distribution was also investigated. Under a natural rainfall scenario, the model showed similarities to previous models. When irrigation is applied, dry stress is alleviated, leading to larger areas modelled climatically suitable compared with previous models, which provided a better fit with the actual distribution of the species. The main areas at risk of invasion by V. germanica include western USA, Mexico, small areas in Central America and in the north-western region of South America, eastern Brazil, western Russia, north-western China, Japan, the Mediterranean coastal regions of North Africa, and parts of southern and eastern Africa.

  10. Modelling of evaporation in a sparse millet crop using a two-source model including sensible heat advection within the canopy

    Science.gov (United States)

    Lund, M. R.; Soegaard, H.

    2003-09-01

    During two successive growing seasons meteorological measurements were made in a pearl millet field in the Sahel to investigate the evaporation process in relation to crop growth. The evaporation was measured by eddy correlation and simulated using the Shuttleworth Wallace (SW) model [Q. J. R. Meteorol. Soc. 111 (1985) 839-855]. To take sun height and multi-layer scattering into account a radiation balance model was formulated. The model indicates that partitioning of the net radiation between the vegetation and the soil may be estimated ( r2=0.94) from the fraction of diffuse radiation, the leaf area index and an attenuation coefficient, but that the attenuation coefficient may not be similar in different locations. To solve the SW-model with respect to the soil resistance an iterative solution was employed with the total evaporation estimated from the Bowen-ratio calculated from eddy correlation measurements. The procedure made it possible to derive stable estimates of soil resistance at soil evaporation rates down to 25 W m -2. The soil resistance was found to be in accordance with evaporation through a dry surface layer. The SW-model indicates, that advection of sensible heat from the dry soil to the plants, increases transpiration considerably. This will cause management techniques, such as mulching and dry farming, aimed at reducing soil evaporation to be less effective than might be anticipated. The effects of raising the leaf area index to improve the microclimate is discussed in relation to management of the available water and crop security.

  11. Power flow modeling of Back-to-Back STATCOM: Comprehensive simulation studies including PV curves and PQ circles

    Directory of Open Access Journals (Sweden)

    Ahmet Mete Vural

    2017-09-01

    Full Text Available Power flow study in a power network embedded with FACTS device requires effort in program coding. Moreover, Newton-Raphson method should be modified by embedding injected power components into the algorithm. In this study, we have proposed a method for modeling of one of the newest FACTS concepts in power flow study without program coding or modification of existing Newton-Raphson algorithm. Real and reactive power injections for each voltage source converter of Back-to-Back Static Synchronous Compensator (BtB-STATCOM are PI regulated to their desired steady-state values. With this respect, reactive power injection of each voltage source converter as well as real power transfer among them can be assigned as control constraint. Operating losses are also taken into account in the proposed modeling approach. Furthermore, proposed model can be easily modified for the modeling of conventional STATCOM having only one voltage source converter or two STATCOMs operating independently. The proposed modeling approach is verified in PSCAD through a number of simulation scenarios in BtB-STATCOM and STATCOM embedded power systems, namely 1-Machine 4-Bus system and 3-Machine 7-Bus system. PV curves of local buses compensated by BtB-STATCOM and STATCOM are presented and compared. Steady-state performance of BtB-STATCOM and STATCOM is also compared in power flow handling.

  12. Improved performance of hybrid photovoltaic-trigeneration systems over photovoltaic-cogen systems including effects of battery storage

    International Nuclear Information System (INIS)

    Nosrat, Amir H.; Swan, Lukas G.; Pearce, Joshua M.

    2013-01-01

    Recent work has proposed that hybridization of residential-scale cogeneration with roof-mounted solar PV (photovoltaic) arrays can increase the PV penetration level in ideal situations by a factor of five. In regions where there is a significant cooling load PV-cogen hybrid systems could be coupled to an absorption chiller to utilize waste heat from the cogen unit. In order to investigate realistic (non-ideal) loads that such a hybrid system would need to service, a new numerical simulation called PVTOM (PV-trigeneration optimization model) was created and coupled to the results of the established CHREM (Canadian Hybrid Residential End-Use Energy and Emissions Model). In this paper, PVTOM is applied to representative houses in select Canadian regions, which experience cooling loads, to assess the fuel utilization efficiency and reduction in greenhouse gas emissions from hybrid PV-cogen and trigen systems in comparison with conventional systems. Results of the optimization runs are provided and the efficacy of PV-cogen and PV-trigen systems is discussed. Both PV-trigen and PV-cogen systems have demonstrated to be more effective at reducing emissions when compared to the current combination of centralized power plants and household heating technologies in some regions. -- Highlights: ► Hybridization of cogeneration with solar photovoltaics (PV) increases PV penetration. ► PV-cogen hybrid systems could be coupled to an absorption chiller to use waste heat. ► Numerical simulation of PVTOM (PV-trigeneration optimization model) was developed. ► Coupled to CHREM (Canadian Hybrid Residential End-Use Energy and Emissions Model). ► Results of the optimization runs show the efficacy of PV-cogen and PV-trigen systems.

  13. A moving boundary problem and orthogonal collocation in solving a dynamic liquid surfactant membrane model including osmosis and breakage

    Directory of Open Access Journals (Sweden)

    E.C. Biscaia Junior

    2001-06-01

    Full Text Available A dynamic kinetic-diffusive model for the extraction of metallic ions from aqueous liquors using liquid surfactant membranes is proposed. The model incorporates undesirable intrinsic phenomena such as swelling and breakage of the emulsion globules that have to be controlled during process operation. These phenomena change the spatial location of the chemical reaction during the course of extraction, resulting in a transient moving boundary problem. The orthogonal collocation method was used to transform the partial differential equations into an ordinary differential equation set that was solved by an implicit numerical routine. The model was found to be numerically stable and reliable in predicting the behaviour of zinc extraction with acidic extractant for long residence times.

  14. Description of premixing with the MC3D code including molten jet behavior modeling. Comparison with FARO experimental results

    Energy Technology Data Exchange (ETDEWEB)

    Berthoud, G.; Crecy, F. de; Meignen, R.; Valette, M. [CEA-G, DRN/DTP/SMTH, 17 rue des Martyrs, 38054 Grenoble Cedex 9 (France)

    1998-01-01

    The premixing phase of a molten fuel-coolant interaction is studied by the way of mechanistic multidimensional calculation. Beside water and steam, corium droplet flow and continuous corium jet flow are calculated independent. The 4-field MC3D code and a detailed hot jet fragmentation model are presented. MC3D calculations are compared to the FARO L14 experiment results and are found to give satisfactory results; heat transfer and jet fragmentation models are still to be improved to predict better final debris size values. (author)

  15. Toward including the effect of manufacturing processes in the pre-estimated losses of the switched reluctance motor

    Directory of Open Access Journals (Sweden)

    Eyhab El-Kharahi

    2015-03-01

    Full Text Available The estimation of losses plays a key role in the process of building any electrical machine. How to estimate those losses while designing any machine; by obtaining the characteristic of the electrical steel from the catalogue and calculate the losses. However, this way is inaccurate since the electrical steel performs several manufacturing processes during the process of building any machine, which affects directly the magnetic property of the electrical steel and accordingly the characteristic of the electrical steel will be affected. That means the B–H curve of the steel that was obtained from the catalogue will be changed. Moreover, during loading and rotating the machine, some important changes occur to the B–H characteristic of the electrical steel such as the stress on the laminated iron. Accordingly, the pre-estimated losses are completely far from the actual losses because they were estimated based on the data of the electrical steel obtained from the catalogue. So in order to estimate the losses precisely significant factors of the manufacturing processes must be included. The paper introduces the systematic estimation of the losses including the effect of one of the manufacturing factors. Similarly, any other manufacturing factor can be included in the pre-designed losses estimations.

  16. Including sorption to black carbon in modelling bioaccumulation of polycyclic aromatic hydrocarbons: Uncertainty analysis and comparison with field data

    NARCIS (Netherlands)

    Hauck, M.; Hendriks, A.J.; Huijbregts, M.J.A.; Koelmans, A.A.; Heuvel-Greve, van den M.J.; Moermond, C.T.A.; Veltman, K.; Vethaak, A.D.

    2007-01-01

    Model estimations of bioaccumulation of polycyclic aromatic hydrocarbons (PAHs) have been higher than field or laboratory data. This has been explained by strong sorption to black carbon (BC). In this paper, eight previously published bioaccumulation datasets were reinterpreted in terms of

  17. 2D Numerical Modelling of the Resin Injection Pultrusion Process Including Experimental Resin Kinetics and Temperature Validation

    DEFF Research Database (Denmark)

    Rasmussen, Filip Salling; Sonne, Mads Rostgaard; Larsen, Martin

    In the present study, a two-dimensional (2D) transient Eulerian thermo-chemical analysis of a carbon fibre epoxy thermosetting Resin Injection Pultrusion (RIP) process is carried out. The numerical model is implemented using the well known unconditionally stable Alternating Direction Implicit (ADI...... inside the composite profile are validated by comparison with experimental measurements and good agreement is found....

  18. A Numerical Model of an Acoustic Metamaterial Using the Boundary Element Method Including Viscous and Thermal Losses

    DEFF Research Database (Denmark)

    Cutanda Henriquez, Vicente; Andersen, Peter Risby; Jensen, Jakob Søndergaard

    2016-01-01

    In recent years, boundary element method (BEM) and finite element method (FEM) implementations of acoustics in fluids with viscous and thermal losses have been developed. They are based on the linearized Navier–Stokes equations with no flow. In this paper, such models with acoustic losses are app...

  19. Application Of A New Semi-Empirical Model For Forming Limit Prediction Of Sheet Material Including Superposed Loads Of Bending And Shearing

    Science.gov (United States)

    Held, Christian; Liewald, Mathias; Schleich, Ralf; Sindel, Manfred

    2010-06-01

    The use of lightweight materials offers substantial strength and weight advantages in car body design. Unfortunately such kinds of sheet material are more susceptible to wrinkling, spring back and fracture during press shop operations. For characterization of capability of sheet material dedicated to deep drawing processes in the automotive industry, mainly Forming Limit Diagrams (FLD) are used. However, new investigations at the Institute for Metal Forming Technology have shown that High Strength Steel Sheet Material and Aluminum Alloys show increased formability in case of bending loads are superposed to stretching loads. Likewise, by superposing shearing on in plane uniaxial or biaxial tension formability changes because of materials crystallographic texture. Such mixed stress and strain conditions including bending and shearing effects can occur in deep-drawing processes of complex car body parts as well as subsequent forming operations like flanging. But changes in formability cannot be described by using the conventional FLC. Hence, for purpose of improvement of failure prediction in numerical simulation codes significant failure criteria for these strain conditions are missing. Considering such aspects in defining suitable failure criteria which is easy to implement into FEA a new semi-empirical model has been developed considering the effect of bending and shearing in sheet metals formability. This failure criterion consists of the combination of the so called cFLC (combined Forming Limit Curve), which considers superposed bending load conditions and the SFLC (Shear Forming Limit Curve), which again includes the effect of shearing on sheet metal's formability.

  20. Application Of A New Semi-Empirical Model For Forming Limit Prediction Of Sheet Material Including Superposed Loads Of Bending And Shearing

    International Nuclear Information System (INIS)

    Held, Christian; Liewald, Mathias; Schleich, Ralf; Sindel, Manfred

    2010-01-01

    The use of lightweight materials offers substantial strength and weight advantages in car body design. Unfortunately such kinds of sheet material are more susceptible to wrinkling, spring back and fracture during press shop operations. For characterization of capability of sheet material dedicated to deep drawing processes in the automotive industry, mainly Forming Limit Diagrams (FLD) are used. However, new investigations at the Institute for Metal Forming Technology have shown that High Strength Steel Sheet Material and Aluminum Alloys show increased formability in case of bending loads are superposed to stretching loads. Likewise, by superposing shearing on in plane uniaxial or biaxial tension formability changes because of materials crystallographic texture. Such mixed stress and strain conditions including bending and shearing effects can occur in deep-drawing processes of complex car body parts as well as subsequent forming operations like flanging. But changes in formability cannot be described by using the conventional FLC. Hence, for purpose of improvement of failure prediction in numerical simulation codes significant failure criteria for these strain conditions are missing. Considering such aspects in defining suitable failure criteria which is easy to implement into FEA a new semi-empirical model has been developed considering the effect of bending and shearing in sheet metals formability. This failure criterion consists of the combination of the so called cFLC (combined Forming Limit Curve), which considers superposed bending load conditions and the SFLC (Shear Forming Limit Curve), which again includes the effect of shearing on sheet metal's formability.

  1. The Effects of including a replacement questionnaire in the first follow-up to an industrial population

    DEFF Research Database (Denmark)

    Mortensen, Peter Stendahl

    2006-01-01

    was identical in all cases. The study compared the impact on response rates, costs, timeliness and quality. The response rate between the first and second reminders was significantly higher in the replacement group, but the second reminder evens out most of this difference. In addition, logistic-regression......  This study reports on a field experiment in which the effects of manipulating the contents of the first reminder in an industrial survey were investigated. Every second non-responding company received a replacement questionnaire with the first mailed reminder, while the second reminder...... models revealed significant differences in the reaction from different industries and regions. For the replacement group, the cost/response rate was 20% higher and the marginal cost per extra response was four times that of the responses to the first mailing. However, the questionnaires were returned...

  2. Potential of the Galaxy from the Besançon galaxy model including non-axisymmetric components: Preliminary results

    Science.gov (United States)

    Fernández-Trincado, J. G.; Robin, A. C.; Bienaymé, O.; Reylé, C.; Valenzuela, O.; Pichardo, B.

    2014-07-01

    In this contributed poster we present a preliminary attempt to compute a non-axisymmetric potential together with previous axisymmetric potential of the Besançon galaxy model. The contribution by non-axisymmetric components are modeled by the superposition of inhomogeneous ellipsoids to approximate the triaxial bar and superposition of homogeneous oblate spheroids for a stellar halo, possibly triaxial. Finally, we have computed the potential and force field for these non-axisymmetric components in order to constraint the total mass of the Milky Way. We present preliminary results for the rotation curve and the contribution of the bar to it. This approach will allow future studies of dynamical constraints from comparisons of kinematical simulations with upcoming surveys such as RAVE, BRAVA, APOGEE, and GAIA in the near future. More details, are presented in https://gaia.ub.edu/Twiki/pub/GREATITNFC/ProgramFinalconference/Poster_JG.Fern%e1ndez.pdf.

  3. State Token Petri Net modeling method for formal verification of computerized procedure including operator's interruptions of procedure execution flow

    International Nuclear Information System (INIS)

    Kim, Yun Goo; Seong, Poong Hyun

    2012-01-01

    The Computerized Procedure System (CPS) is one of the primary operating support systems in the digital Main Control Room. The CPS displays procedure on the computer screen in the form of a flow chart, and displays plant operating information along with procedure instructions. It also supports operator decision making by providing a system decision. A procedure flow should be correct and reliable, as an error would lead to operator misjudgement and inadequate control. In this paper we present a modeling for the CPS that enables formal verification based on Petri nets. The proposed State Token Petri Nets (STPN) also support modeling of a procedure flow that has various interruptions by the operator, according to the plant condition. STPN modeling is compared with Coloured Petri net when they are applied to Emergency Operating Computerized Procedure. A converting program for Computerized Procedure (CP) to STPN has been also developed. The formal verification and validation methods of CP with STPN increase the safety of a nuclear power plant and provide digital quality assurance means that are needed when the role and function of the CPS is increasing.

  4. Coupled physical/biogeochemical modeling including O2-dependent processes in the Eastern Boundary Upwelling Systems: application in the Benguela

    Directory of Open Access Journals (Sweden)

    E. Gutknecht

    2013-06-01

    Full Text Available The Eastern Boundary Upwelling Systems (EBUS contribute to one fifth of the global catches in the ocean. Often associated with Oxygen Minimum Zones (OMZs, EBUS represent key regions for the oceanic nitrogen (N cycle. Important bioavailable N loss due to denitrification and anammox processes as well as greenhouse gas emissions (e.g, N2O occur also in these EBUS. However, their dynamics are currently crudely represented in global models. In the climate change context, improving our capability to properly represent these areas is crucial due to anticipated changes in the winds, productivity, and oxygen content. We developed a biogeochemical model (BioEBUS taking into account the main processes linked with EBUS and associated OMZs. We implemented this model in a 3-D realistic coupled physical/biogeochemical configuration in the Namibian upwelling system (northern Benguela using the high-resolution hydrodynamic ROMS model. We present here a validation using in situ and satellite data as well as diagnostic metrics and sensitivity analyses of key parameters and N2O parameterizations. The impact of parameter values on the OMZ off Namibia, on N loss, and on N2O concentrations and emissions is detailed. The model realistically reproduces the vertical distribution and seasonal cycle of observed oxygen, nitrate, and chlorophyll a concentrations, and the rates of microbial processes (e.g, NH4+ and NO2− oxidation, NO3− reduction, and anammox as well. Based on our sensitivity analyses, biogeochemical parameter values associated with organic matter decomposition, vertical sinking, and nitrification play a key role for the low-oxygen water content, N loss, and N2O concentrations in the OMZ. Moreover, the explicit parameterization of both steps of nitrification, ammonium oxidation to nitrate with nitrite as an explicit intermediate, is necessary to improve the representation of microbial activity linked with the OMZ. The simulated minimum oxygen

  5. Stochastic dynamic simulation modeling including multitrait genetics to estimate genetic, technical, and financial consequences of dairy farm reproduction and selection strategies.

    Science.gov (United States)

    Kaniyamattam, K; Elzo, M A; Cole, J B; De Vries, A

    2016-10-01

    The objective of this study was to develop a daily stochastic dynamic dairy simulation model that included multitrait genetics and to evaluate the effects of reduced genetic models and various reproduction and selection strategies on the genetic, technical, and financial performance of a dairy herd. The 12 correlated genetic traits included in the 2014 lifetime net merit (NM$) index were modeled for each animal. For each animal, a true breeding value (TBV) for each trait was calculated as the average of the sire's and dam's TBV, plus a fraction of the inbreeding and Mendelian sampling variability. Similarly, an environmental component for each trait was calculated and was partitioned into a permanent and a daily (temporary) effect. The combined TBV and environmental effects were converted into the phenotypic performance of each animal. Hence, genetics and phenotypic performances were associated. Estimated breeding values (EBV) were also simulated. Genetic trends for each trait for the service sire were based on expected trends in US Holsteins. Surplus heifers were culled based on various ranking criteria to maintain a herd size of 1,000 milking cows. In the first 8 scenarios, culling of surplus heifers was either random or based on the EBV of NM$. Four different genetic models, depending on the presence or absence of genetic trends or genetic and environmental correlations, or both, were evaluated to measure the effect of excluding multitrait genetics on animal performance. In the last 5 scenarios, the full genetic model was used and culling of surplus heifers was either random or based on the EBV of NM$ or the EBV of milk. Sexed semen use and reliability of the EBV were also varied. Each scenario was simulated for 15yr into the future. Results showed that genetic models without all 12 genetic trends and genetic and environmental correlations provided biased estimates of the genetic, technical, and financial performance of the dairy herd. Average TBV of NM$ of all

  6. Measured Properties of Turbulent Premixed Flames for Model Assessment, Including Burning Velocities, Stretch Rates, and Surface Densities (Postprint)

    Science.gov (United States)

    2006-10-01

    conditions was stabilized on a large two-dimensional slot Bunsen burner . It was found that the turbulent burning velocity of Bunsen flames depends...burning velocity of Bunsen flames are inadequate because they should include two additional parameters: mean velocity Ū and burner width W. These...corru- gated) flame with well-defined boundary conditions was stabilized on a large two-dimensional slot Bunsen burner . It was found that the turbulent

  7. Including the Copenhagen Adduction Exercise in the FIFA 11+ Provides Missing Eccentric Hip Adduction Strength Effect in Male Soccer Players

    DEFF Research Database (Denmark)

    Harøy, Joar; Thorborg, Kristian; Serner, Andreas

    2017-01-01

    BACKGROUND: The FIFA 11+ was developed as a complete warm-up program to prevent injuries in soccer players. Although reduced hip adduction strength is associated with groin injuries, none of the exercises included in the FIFA 11+ seem to specifically target hip adduction strength. PURPOSE......: To investigate the effect on eccentric hip adduction strength of the FIFA 11+ warm-up program with or without the Copenhagen adduction exercise. STUDY DESIGN: Randomized controlled trial; Level of evidence, 1. METHODS: We recruited 45 eligible players from 2 U19 elite male soccer teams. Players were randomized...... into 2 groups; 1 group carried out the standard FIFA 11+ program, while the other carried out the FIFA 11+ but replaced the Nordic hamstring exercise with the Copenhagen adduction exercise. Both groups performed the intervention 3 times weekly for 8 weeks. Players completed eccentric strength and sprint...

  8. Modeling Incoherent Electron Cloud Effects

    International Nuclear Information System (INIS)

    Vay, Jean-Luc; Benedetto, E.; Fischer, W.; Franchetti, G.; Ohmi, K.; Schulte, D.; Sonnad, K.; Tomas, R.; Vay, J.-L.; Zimmermann, F.; Rumolo, G.; Pivi, M.; Raubenheimer, T.

    2007-01-01

    Incoherent electron effects could seriously limit the beam lifetime in proton or ion storage rings, such as LHC, SPS, or RHIC, or blow up the vertical emittance of positron beams, e.g., at the B factories or in linear-collider damping rings. Different approaches to modeling these effects each have their own merits and drawbacks. We describe several simulation codes which simplify the descriptions of the beam-electron interaction and of the accelerator structure in various different ways, and present results for a toy model of the SPS. In addition, we present evidence that for positron beams the interplay of incoherent electron-cloud effects and synchrotron radiation can lead to a significant increase in vertical equilibrium emittance. The magnitude of a few incoherent e+e- scattering processes is also estimated. Options for future code development are reviewed

  9. Enhanced Precision of the New Hologic Horizon Model Compared With the Old Discovery Model Is Less Evident When Fewer Vertebrae Are Included in the Analysis.

    Science.gov (United States)

    McNamara, Elizabeth A; Kilim, Holly P; Malabanan, Alan O; Whittaker, LaTarsha G; Rosen, Harold N

    The International Society for Clinical Densitometry guidelines recommend using locally derived precision data for spine bone mineral densities (BMDs), but do not specify whether data derived from L1-L4 spines correctly reflect the precision for spines reporting fewer than 4 vertebrae. Our experience suggested that the decrease in precision with successively fewer vertebrae is progressive as more vertebrae are excluded and that the precision for the newer Horizon Hologic model might be better than that for the previous model, and we sought to quantify. Precision studies were performed on Hologic densitometers by acquiring spine BMD in fast array mode twice on 30 patients, according to International Society for Clinical Densitometry guidelines. This was done 10 different times on various Discovery densitometers, and once on a Horizon densitometer. When 1 vertebral body was excluded from analysis, there was no significant deterioration in precision. When 2 vertebrae were excluded, there was a nonsignificant trend to poorer precision, and when 3 vertebrae were excluded, there was significantly worse precision. When 3 or 4 vertebrae were reported, the precision of the spine BMD measurement was significantly better on the Hologic Horizon than on the Discovery, but the difference in precision between densitometers narrowed and was no longer significant when 1 or 2 vertebrae were reported. The results suggest that (1) the measurement of in vivo spine BMD on the new Hologic Horizon densitometer is significantly more precise than on the older Discovery model; (2) the difference in precision between the Horizon and Discovery models decreases as fewer vertebrae are included; (3) the measurement of spine BMD is less precise as more vertebrae are excluded, but still quite reasonable even when only 1 vertebral body is included; and (4) when 3 vertebrae are reported, L1-L4 precision data can reasonably be used to report significance of changes in BMD. When 1 or 2 vertebrae are

  10. SU-E-J-215: Onboard Split PET Including the Effects of Attenuation, Scatter, and Random Events

    Energy Technology Data Exchange (ETDEWEB)

    Darwish, N [Rush University Medical Center, Chicago, IL (United States); Kao, C [The University of Chicago, Chicago, IL (United States); Thomadsen, B; Mackie, T [University of Wisconsin, Madison, WI (United States)

    2014-06-01

    Purpose: Positron emission tomography (PET) using split PET geometry was investigated as an on-board system for functional imaging and PET marker tracking, specifically with tomotherapy. The open dual ring PET would allow measurement of both inter and intra-fractional variation, improving the delineation of tumor volume at any stage in the radiation treatment delivery process. We present results from data obtained using Monte Carlo simulations including the effects of attenuation, random events, and scatter. Methods: PET design was accomplished via Monte Carlo simulations with GATE, the Geant4 Application for Emission Tomography. Images were reconstructed using Software for Image Reconstruction (STIR) with a fully 3D ordered subset expectation maximization (OSEM) image reconstruction technique. Results: Monte Carlo simulations of the split PET geometry indicate that including physical factors that degrade image quality such as attenuation, random events, and scatter still prove the feasibility of near real-time PET for both inter and intra-fractional radiation delivery. The image quality of scan times under 1 minute reveals that it is possible to utilize PET scanning and reconstruction during the treatment session intrafractionally. GATE also simulates the depth information but does not correct obliqueness of the path of line of response so the data is much more realistic than the data obtained with ray tracing. Conclusion: Onboard split PET with TomoTherapy can generate quality images under 1 minute scan times without the need to correct for attenuation, scatter, random events, or depth information of the interaction.

  11. Modeling gamma-ray burst observations by Fermi and MAGIC including attenuation due to diffuse background light

    OpenAIRE

    Gilmore, Rudy C.; Prada, Francisco; Primack, Joel R.

    2009-01-01

    Gamma rays from extragalactic sources are attenuated by pair-production interactions with diffuse photons of the extragalactic background light (EBL). Gamma-ray bursts (GRBs) are a source of high-redshift photons above 10 GeV, and could be therefore useful as a probe of the evolving UV background radiation. In this paper, we develop a simple phenomenological model for the number and redshift distribution of gamma-ray bursts that can be seen at GeV energies with the Fermi satellite and MAGIC a...

  12. Search for Non-Standard Model Behavior, including CP Violation, in Higgs Production and Decay to $ZZ^{*}$

    CERN Document Server

    Webster, Jordan

    This thesis presents an ATLAS study of the tensor structure characterizing the interaction of the scalar Higgs boson with two $Z$ bosons. The measurement is based on $25~\\textrm{fb}^{-1}$ of proton-proton collision data produced at the Large Hadron Collider with center of mass energy equal to 7 and $8~\\textrm{TeV}$. Nine discriminant observables in the four lepton final state are used to search for CP-odd and CP-even components in the Lagrangian beyond those of the Standard Model. These are represented by $(\\tilde{\\kappa}_{AVV}/\\kappa_{SM})\\tan\\alpha$ and $\\tilde{\\kappa}_{HVV}/\\kappa_{SM}$, respectively. Both of these parameters are found to be consistent with their predicted Standard Model values of zero. Values outside the intervals $-3.24<(\\tilde{\\kappa}_{AVV}/\\kappa_{SM})\\tan\\alpha<0.91$ and $-0.82<\\tilde{\\kappa}_{HVV}/\\kappa_{SM}<0.87$ are excluded at 95\\% confidence level. These results are combined with a search for the same structure in the interaction of the Higgs with pairs of $W$ boson...

  13. Segment Tracking via a Spatiotemporal Linking Process including Feedback Stabilization in an n-D Lattice Model

    Directory of Open Access Journals (Sweden)

    Florentin Wörgötter

    2009-11-01

    Full Text Available Model-free tracking is important for solving tasks such as moving-object tracking and action recognition in cases where no prior object knowledge is available. For this purpose, we extend the concept of spatially synchronous dynamics in spin-lattice models to the spatiotemporal domain to track segments within an image sequence. The method is related to synchronization processes in neural networks and based on superparamagnetic clustering of data. Spin interactions result in the formation of clusters of correlated spins, providing an automatic labeling of corresponding image regions. The algorithm obeys detailed balance. This is an important property as it allows for consistent spin-transfer across subsequent frames, which can be used for segment tracking. Therefore, in the tracking process the correct equilibrium will always be found, which is an important advance as compared with other more heuristic tracking procedures. In the case of long image sequences, i.e., movies, the algorithm is augmented with a feedback mechanism, further stabilizing segment tracking.

  14. Three dimensional model for particle saltation close to stream beds, including a detailed description of the particle interaction with turbulence and inter-particle collisions

    KAUST Repository

    Moreno, Pablo M.

    2011-05-19

    We present in this paper a new three-dimensional (3-D) model for bed-load sediment transport, based on a Lagrangian description. We analyze generalized sub-models for the velocities after collision and the representation of the bed-roughness. The free-flight sub-model includes the effect of several forces, such as buoyancy, drag, virtual mass, lift, Basset and Magnus, and also addresses the particle rotation. A recent methodology for saving computational time in the Basset force is also employed. The sub-models for the post-collision velocity and rotation are based on the conservation of linear and angular momentum during the collision with the bed. We develop a new 3-D representation for the bed roughness by using geometric considerations. In order to address the interaction of particles with the turbulent flow, we tracked the particles through a computed turbulent velocity field for a smooth flat plate. This velocity field was used as a surrogate of the 3-D turbulent conditions close to the bed in streams. We first checked that the basic turbulence statistics for this velocity field could be used to approximate those in an open-channel flow. We then analyzed the interaction of the sediment and the turbulence for a single and multiple particles. We compared numerical results with experimental data obtained by Niño and García (1998b). We show that model predictions are in good agreement with existing data, in the sand size range. © 2011 ASCE.

  15. Spectral element modelling of wave propagation in isotropic and anisotropic shell-structures including different types of damage

    International Nuclear Information System (INIS)

    Schulte, R T; Fritzen, C-P; Moll, J

    2010-01-01

    During the last decades, guided waves have shown great potential for Structural Health Monitoring (SHM) applications. These waves can be excited and sensed by piezoelectric elements that can be permanently attached onto a structure offering online monitoring capability. However, the setup of wave based SHM systems for complex structures may be very difficult and time consuming. For that reason there is a growing demand for efficient simulation tools providing the opportunity to design wave based SHM systems in a virtual environment. As usually high frequency waves are used, the associated short wavelength leads to the necessity of a very dense mesh, which makes conventional finite elements not well suited for this purpose. Therefore in this contribution a flat shell spectral element approach is presented. By including electromechanical coupling a SHM system can be simulated entirely from actuator voltage to sensor voltage. Besides a comparison to measured data for anisotropic materials including delamination, a numerical example of a more complex, stiffened shell structure with debonding is presented.

  16. Analytic model for the long-term evolution of circular Earth satellite orbits including lunar node regression

    Science.gov (United States)

    Zhu, Ting-Lei; Zhao, Chang-Yin; Zhang, Ming-Jiang

    2017-04-01

    This paper aims to obtain an analytic approximation to the evolution of circular orbits governed by the Earth's J2 and the luni-solar gravitational perturbations. Assuming that the lunar orbital plane coincides with the ecliptic plane, Allan and Cook (Proc. R. Soc. A, Math. Phys. Eng. Sci. 280(1380):97, 1964) derived an analytic solution to the orbital plane evolution of circular orbits. Using their result as an intermediate solution, we establish an approximate analytic model with lunar orbital inclination and its node regression be taken into account. Finally, an approximate analytic expression is derived, which is accurate compared to the numerical results except for the resonant cases when the period of the reference orbit approximately equals the integer multiples (especially 1 or 2 times) of lunar node regression period.

  17. OBLIMAP 2.0: a fast climate model–ice sheet model coupler including online embeddable mapping routines

    Directory of Open Access Journals (Sweden)

    T. J. Reerink

    2016-11-01

    Full Text Available This paper accompanies the second OBLIMAP open-source release. The package is developed to map climate fields between a general circulation model (GCM and an ice sheet model (ISM in both directions by using optimal aligned oblique projections, which minimize distortions. The curvature of the surfaces of the GCM and ISM grid differ, both grids may be irregularly spaced and the ratio of the grids is allowed to differ largely. OBLIMAP's stand-alone version is able to map data sets that differ in various aspects on the same ISM grid. Each grid may either coincide with the surface of a sphere, an ellipsoid or a flat plane, while the grid types might differ. Re-projection of, for example, ISM data sets is also facilitated. This is demonstrated by relevant applications concerning the major ice caps. As the stand-alone version also applies to the reverse mapping direction, it can be used as an offline coupler. Furthermore, OBLIMAP 2.0 is an embeddable GCM–ISM coupler, suited for high-frequency online coupled experiments. A new fast scan method is presented for structured grids as an alternative for the former time-consuming grid search strategy, realising a performance gain of several orders of magnitude and enabling the mapping of high-resolution data sets with a much larger number of grid nodes. Further, a highly flexible masked mapping option is added. The limitation of the fast scan method with respect to unstructured and adaptive grids is discussed together with a possible future parallel Message Passing Interface (MPI implementation.

  18. The albino chick as a model for studying ocular developmental anomalies, including refractive errors, associated with albinism.

    Science.gov (United States)

    Rymer, Jodi; Choh, Vivian; Bharadwaj, Shrikant; Padmanabhan, Varuna; Modilevsky, Laura; Jovanovich, Elizabeth; Yeh, Brenda; Zhang, Zhan; Guan, Huanxian; Payne, W; Wildsoet, Christine F

    2007-10-01

    Albinism is associated with a variety of ocular anomalies including refractive errors. The purpose of this study was to investigate the ocular development of an albino chick line. The ocular development of both albino and normally pigmented chicks was monitored using retinoscopy to measure refractive errors and high frequency A-scan ultrasonography to measure axial ocular dimensions. Functional tests included an optokinetic nystagmus paradigm to assess visual acuity, and flash ERGs to assess retinal function. The underlying genetic abnormality was characterized using a gene microarray, PCR and a tyrosinase assay. The ultrastructure of the retinal pigment epithelium (RPE) was examined using transmission electron microscopy. PCR confirmed that the genetic abnormality in this line is a deletion in exon 1 of the tyrosinase gene. Tyrosinase gene expression in isolated RPE cells was minimally detectable, and there was minimal enzyme activity in albino feather bulbs. The albino chicks had pink eyes and their eyes transilluminated, reflecting the lack of melanin in all ocular tissues. All three main components, anterior chamber, crystalline lens and vitreous chamber, showed axial expansion over time in both normal and albino animals, but the anterior chambers of albino chicks were consistently shallower than those of normal chicks, while in contrast, their vitreous chambers were longer. Albino chicks remained relatively myopic, with higher astigmatism than the normally pigmented chicks, even though both groups underwent developmental emmetropization. Albino chicks had reduced visual acuity yet the ERG a- and b-wave components had larger amplitudes and shorter than normal implicit times. Developmental emmetropization occurs in the albino chick but is impaired, likely because of functional abnormalities in the RPE and/or retina as well as optical factors. In very young chicks the underlying genetic mutation may also contribute to refractive error and eye shape abnormalities.

  19. Migration of antioxidants from polylactic acid films, a parameter estimation approach: Part I - A model including convective mass transfer coefficient.

    Science.gov (United States)

    Samsudin, Hayati; Auras, Rafael; Burgess, Gary; Dolan, Kirk; Soto-Valdez, Herlinda

    2018-03-01

    A two-step solution based on the boundary conditions of Crank's equations for mass transfer in a film was developed. Three driving factors, the diffusion (D), partition (K p,f ) and convective mass transfer coefficients (h), govern the sorption and/or desorption kinetics of migrants from polymer films. These three parameters were simultaneously estimated. They provide in-depth insight into the physics of a migration process. The first step was used to find the combination of D, K p,f and h that minimized the sums of squared errors (SSE) between the predicted and actual results. In step 2, an ordinary least square (OLS) estimation was performed by using the proposed analytical solution containing D, K p,f and h. Three selected migration studies of PLA/antioxidant-based films were used to demonstrate the use of this two-step solution. Additional parameter estimation approaches such as sequential and bootstrap were also performed to acquire a better knowledge about the kinetics of migration. The proposed model successfully provided the initial guesses for D, K p,f and h. The h value was determined without performing a specific experiment for it. By determining h together with D, under or overestimation issues pertaining to a migration process can be avoided since these two parameters are correlated. Copyright © 2017 Elsevier Ltd. All rights reserved.

  20. Modeling a novel CCHP system including solar and wind renewable energy resources and sizing by a CC-MOPSO algorithm

    International Nuclear Information System (INIS)

    Soheyli, Saman; Shafiei Mayam, Mohamad Hossein; Mehrjoo, Mehri

    2016-01-01

    Highlights: • Considering renewable energy resources as the main prime movers in CCHP systems. • Simultaneous application of FEL and FTL by optimizing two probability functions. • Simultaneous optimization the equipment and penalty factors by CC-MOPSO algorithm. • Reducing fuel consumption and pollution up to 263 and 353 times, respectively. - Abstract: Due to problems, such as, heat losses of equipment, low energy efficiency, increasing pollution and the fossil fuels consumption, combined cooling, heating, and power (CCHP) systems have attracted lots of attention during the last decade. In this paper, for minimizing fossil fuel consumption and pollution, a novel CCHP system including photovoltaic (PV) modules, wind turbines, and solid oxide fuel cells (SOFC) as the prime movers is considered. Moreover, in order to minimize the excess electrical and heat energy production of the CCHP system and so reducing the need for the local power grid and any auxiliary heat production system, following electrical load (FEL) and following thermal load (FTL) operation strategies are considered, simultaneously. In order to determine the optimal number of each system component and also set the penalty factors in the used penalty function, a co-constrained multi objective particle swarm optimization (CC-MOPSO) algorithm is applied. Utilization of the renewable energy resources, the annual total cost (ATC) and the CCHP system area are considered as the objective functions. It also includes constraints such as, loss of power supply probability (LPSP), loss of heat supply probability (LHSP), state of battery charge (SOC), and the number of each CCHP component. A hypothetical hotel in Kermanshah, Iran is conducted to verify the feasibility of the proposed system. 10 wind turbines, 430 PV modules, 11 SOFCs, 106 batteries and 2 heat storage tanks (HST) are numerical results for the spring as the best season in terms of decreasing cost and fuel consumption. Comparing the results

  1. A predator-prey model with a holling type I functional response including a predator mutual interference

    Science.gov (United States)

    Seo, G.; DeAngelis, D.L.

    2011-01-01

    The most widely used functional response in describing predator-prey relationships is the Holling type II functional response, where per capita predation is a smooth, increasing, and saturating function of prey density. Beddington and DeAngelis modified the Holling type II response to include interference of predators that increases with predator density. Here we introduce a predator-interference term into a Holling type I functional response. We explain the ecological rationale for the response and note that the phase plane configuration of the predator and prey isoclines differs greatly from that of the Beddington-DeAngelis response; for example, in having three possible interior equilibria rather than one. In fact, this new functional response seems to be quite unique. We used analytical and numerical methods to show that the resulting system shows a much richer dynamical behavior than the Beddington-DeAngelis response, or other typically used functional responses. For example, cyclic-fold, saddle-fold, homoclinic saddle connection, and multiple crossing bifurcations can all occur. We then use a smooth approximation to the Holling type I functional response with predator mutual interference to show that these dynamical properties do not result from the lack of smoothness, but rather from subtle differences in the functional responses. ?? 2011 Springer Science+Business Media, LLC.

  2. Effect on attendance by including focused information on spirometry in preventive health checks: study protocol for a randomized controlled trial.

    Science.gov (United States)

    Ørts, Lene Maria; Løkke, Anders; Bjerregaard, Anne-Louise; Maindal, Helle Terkildsen; Sandbæk, Annelli

    2016-12-01

    Early detection of lung diseases can help to reduce their severity. Lung diseases are among the most frequently occurring and serious diseases worldwide; nonetheless, many patients remain undiagnosed. Preventive health checks including spirometry can detect lung diseases at early stages; however, recruitment for health checks remains a challenge, and little is known about what motivates the attendance. The aim of the study is to examine whether focused information on spirometry in the invitation compared to general information will impact the attendance rate in preventive health checks. This randomized, controlled trial tests the effect of information on spirometry embedded in the Check your Health Preventive Program (CHPP). The CHPP is an open-label, household cluster-randomized, controlled trial offering a preventive health check to 30- to -49-year-olds in a Danish municipality from 2012 to 2017 (n = 26,216). During 2015-2016, 4356 citizens aged 30-49 years will be randomized into two groups. The intervention group receives an invitation which highlights the value and contents of spirometry as part of a health check and information about lung diseases. The comparison group receives a standard invitation containing practical information and specifies the contents of the general health check. Outcomes are (1) differences in attendance rates measured by the proportion of citizens attending each of the two study groups and (2) proportion of persons at risk defined by smoking status and self-reported lung symptoms in the study groups. The proportion of participants with abnormal spirometry assessed at the preventive health check will be compared between the two study groups. The results from the present study will inform future recruitment strategies to health checks. The developed material on content, value, and information about lung disease is feasible and transferable to other populations, making it easy to implement if effective. ClinicalTrials.gov: NCT

  3. The effect of slurry treatment including ozonation on odorant reduction measured by in-situ PTR-MS

    Science.gov (United States)

    Liu, Dezhao; Feilberg, Anders; Adamsen, Anders P. S.; Jonassen, Kristoffer E. N.

    2011-07-01

    The emission of odorous compounds from intensive pig production facilities is a nuisance for neighbors. Slurry ozonation for odor abatement has previously been demonstrated in laboratory scale. In this study, the effect of slurry ozonation (combined with solid-liquid pre-separation and acidification) on emissions of odorous compounds was tested in an experimental full-scale growing pig facility using Proton-Transfer-Reaction Mass Spectrometry (PTR-MS) for online analysis of odorants. The measurements were performed to gain a better understanding of the effects of ozone treatment on emissions odorous compounds and to identify potential options for optimization of ozone treatment. The compounds monitored included volatile sulfur compounds, amine, carboxylic acids, ketones, phenols and indoles. Measurements were performed during nearly a one-month period in summertime. The compounds with the highest concentrations observed in the ventilation exhaust duct were acetic acid, hydrogen sulfide, propanoic acid and butanoic acid. The compounds with the highest removal efficiencies were hydrogen sulfide, 3-methyl-indole, phenol and acetic acid. Based on odor threshold values, methanethiol, butanoic acid, 4-methylphenol, hydrogen sulfide and C 5 carboxylic acids are estimated to contribute significantly to the odor nuisance. Emissions of odorous compounds were observed to be strongly correlated with temperature with the exception of hydrogen sulfide. Emission peaks of sulfur compounds were seen during slurry handling activities. Discharging of the slurry pit led to reduced hydrogen sulfide emissions, but emissions of most other odorants were not affected. The results indicate that emissions of odorants other than hydrogen sulfide mainly originate from sources other than the treated slurry, which limits the potential for further optimization. The PTR-MS measurements are demonstrated to provide a quantitative, accurate and detailed evaluation of ozone treatment for emission

  4. Ab initio effective core potentials including relativistic effects and their application to the electronic structure calculations of heavy atoms and molecules

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Y.S.

    1977-11-01

    The effects of the 4f shell of electrons and the relativity of valence electrons are compared. The effect of 4f shell (lanthanide contraction) is estimated from the numerical Hartree-Fock (HF) calculations of pseudo-atoms corresponding to Hf, Re, Au, Hg, Tl, Pb and Bi without 4f electrons and with atomic numbers reduced by 14. The relativistic effect estimated from the numerical Dirac-Hartree-Fock (DHF) calculations of those atoms is comparable in the magnitude with that of the 4f shell of electrons. Both are larger for 6s than for 5d or 6p electrons. The various relativistic effects on valence electrons are discussed in detail to determine the proper level of the approximation for the valence electron calculations of systems with heavy elements. An effective core potential system has been developed for heavy atoms in which relativistic effects are included in the effective potentials.

  5. Integrating Effects-Based and Attrition-Based Modeling

    National Research Council Canada - National Science Library

    DeGregorio, Edward A; Janssen, Raymond A; Wagenhals, Lee W; Messier, Richard H

    2004-01-01

    .... Modeling the NCW EBO process attempts to codify the belief structure and reasoning of adversaries and their cause-effect relationships with US and coalition actions, including mitigating undesired effects...

  6. Off-target effects of sulforaphane include the derepression of long terminal repeats through histone acetylation events.

    Science.gov (United States)

    Baier, Scott R; Zbasnik, Richard; Schlegel, Vicki; Zempleni, Janos

    2014-06-01

    Sulforaphane is a naturally occurring isothiocyanate in cruciferous vegetables. Sulforaphane inhibits histone deacetylases, leading to the transcriptional activation of genes including tumor suppressor genes. The compound has attracted considerable attention in the chemoprevention of prostate cancer. Here we tested the hypothesis that sulforaphane is not specific for tumor suppressor genes but also activates loci such as long terminal repeats (LTRs), which might impair genome stability. Studies were conducted using chemically pure sulforaphane in primary human IMR-90 fibroblasts and in broccoli sprout feeding studies in healthy adults. Sulforaphane (2.0 μM) caused an increase in LTR transcriptional activity in cultured cells. Consumption of broccoli sprouts (34, 68 or 102 g) by human volunteers caused a dose dependent elevation in LTR mRNA in circulating leukocytes, peaking at more than a 10-fold increase. This increase in transcript levels was associated with an increase in histone H3 K9 acetylation marks in LTR 15 in peripheral blood mononuclear cells from subjects consuming sprouts. Collectively, this study suggests that sulforaphane has off-target effects that warrant further investigation when recommending high levels of sulforaphane intake, despite its promising activities in chemoprevention. Copyright © 2014 Elsevier Inc. All rights reserved.

  7. Degeneration of retinal on bipolar cells induced by serum including autoantibody against TRPM1 in mouse model of paraneoplastic retinopathy.

    Directory of Open Access Journals (Sweden)

    Shinji Ueno

    Full Text Available The paraneoplastic retinopathies (PRs are a group of eye diseases characterized by a sudden and progressive dysfunction of the retina caused by an antibody against a protein in a neoplasm. Evidence has been obtained that the transient receptor potential melastatin 1 (TRPM1 protein was one of the antigens for the autoantibody against the ON bipolar cells in PR patients. However, it has not been determined how the autoantibody causes the dysfunction of the ON bipolar cells. We hypothesized that the antibody against TRPM1 in the serum of patients with PR causes a degeneration of retinal ON bipolar cells. To test this hypothesis, we injected the serum from the PR patient, previously shown to contain anti-TRPM1 antibodies by westerblot, intravitreally into mice and examined the effects on the retina. We found that the electroretinograms (ERGs of the mice were altered acutely after the injection, and the shape of the ERGs resembled that of the patient with PR. Immunohistochemical analysis of the eyes injected with the serum showed immunoreactivity against bipolar cells only in wild-type animals and not in TRPM1 knockout mice,consistent with the serum containing anti-TRPM1 antibodies. Histology also showed that some of the bipolar cells were apoptotic by 5 hours after the injection in wild type mice, but no bipolar cell death was found in TRPM1 knockout mice, . At 3 months, the inner nuclear layer was thinner and the amplitudes of the ERGs were still reduced. These results indicate that the serum of a patient with PR contained an antibody against TRPM1 caused an acute death of retinal ON bipolar cells of mice.

  8. Gyrofluid turbulence models with kinetic effects

    Energy Technology Data Exchange (ETDEWEB)

    Dorland, W.; Hammett, G.W.

    1992-12-01

    Nonlinear gyrofluid equations are derived by taking moments of the nonlinear, electrostatic gyrokinetic equation. The principal model presented includes evolution equations for the guiding center n, u[parallel], T[parallel], and T[perpendicular] along with an equation expressing the quasineutrality constraint. Additional evolution equations for higher moments are derived which may be used if greater accuracy is desired. The moment hierarchy is closed with a Landau-damping model which is equivalent to a multi-pole approximation to the plasma dispersion function, extended to include finite Larmor radius effects. In particular, new dissipative, nonlinear terms are found which model the perpendicular phase-mixing of the distribution function along contours of constant electrostatic potential. These FLR phase-mixing'' terms introduce a hyperviscosity-like damping [proportional to] k[sub [perpendicular

  9. Better models are more effectively connected models

    Science.gov (United States)

    Nunes, João Pedro; Bielders, Charles; Darboux, Frederic; Fiener, Peter; Finger, David; Turnbull-Lloyd, Laura; Wainwright, John

    2016-04-01

    The concept of hydrologic and geomorphologic connectivity describes the processes and pathways which link sources (e.g. rainfall, snow and ice melt, springs, eroded areas and barren lands) to accumulation areas (e.g. foot slopes, streams, aquifers, reservoirs), and the spatial variations thereof. There are many examples of hydrological and sediment connectivity on a watershed scale; in consequence, a process-based understanding of connectivity is crucial to help managers understand their systems and adopt adequate measures for flood prevention, pollution mitigation and soil protection, among others. Modelling is often used as a tool to understand and predict fluxes within a catchment by complementing observations with model results. Catchment models should therefore be able to reproduce the linkages, and thus the connectivity of water and sediment fluxes within the systems under simulation. In modelling, a high level of spatial and temporal detail is desirable to ensure taking into account a maximum number of components, which then enables connectivity to emerge from the simulated structures and functions. However, computational constraints and, in many cases, lack of data prevent the representation of all relevant processes and spatial/temporal variability in most models. In most cases, therefore, the level of detail selected for modelling is too coarse to represent the system in a way in which connectivity can emerge; a problem which can be circumvented by representing fine-scale structures and processes within coarser scale models using a variety of approaches. This poster focuses on the results of ongoing discussions on modelling connectivity held during several workshops within COST Action Connecteur. It assesses the current state of the art of incorporating the concept of connectivity in hydrological and sediment models, as well as the attitudes of modellers towards this issue. The discussion will focus on the different approaches through which connectivity

  10. Cost-effectiveness of hematopoietic stem cell mobilization strategies including plerixafor in multiple myeloma and lymphoma patients.

    Science.gov (United States)

    Tichopád, Aleš; Vítová, Veronika; Kořístek, Zdeněk; Lysák, Daniel

    2013-12-01

    Peripheral blood stem cells (PBSCs) are preferred source of hematopoietic stem cells for autologous transplantation. Mobilization of PBSCs using chemotherapy and/or granulocyte colony-stimulating factor (G-CSF) however fails in around 20%. Combining G-CSF with plerixafor increases the mobilizations success. We compared cost-effectiveness of following schemes: the use of plerixafor "on demand" (POD) during the first mobilization in all patients with inadequate response, the remobilization with plerixafor following failure of the first standard mobilization (SSP), and the standard (re)mobilization scheme without plerixafor (SSNP). Decision tree models populated with data from a first-of-a-kind patient registry in six Czech centers (n = 93) were built to compare clinical benefits and direct costs from the payer's perspective. The success rates and costs for POD, SSP and SSNP mobilizations were; 94.9%, $7,197; 94.7%, $8,049; 84.7%, $5,991, respectively. The direct cost per successfully treated patient was $7,586, $8,501, and $7,077, respectively. The cost of re-mobilization of a poor mobilizer was $5,808 with G-CSF only and $16,755 if plerixafor was added. The total cost of plerixafor "on-demand" in the sub-cohort of poor mobilizers was $17,120. Generally, plerixafor improves the mobilization success by 10% and allows an additional patient to be successfully mobilized for incremental $11,803. Plerixafor is better and cheaper if used "on demand" than within a subsequent remobilization. Copyright © 2013 Wiley Periodicals, Inc.

  11. Mathematical model for gyroscope effects

    Science.gov (United States)

    Usubamatov, Ryspek

    2015-05-01

    Gyroscope effects are used in many engineering calculations of rotating parts, and a gyroscope is the basic unit of numerous devices and instruments used in aviation, space, marine and other industries. The primary attribute of a gyroscope is a spinning rotor that persists in maintaining its plane of rotation, creating gyroscope effects. Numerous publications represent the gyroscope theory using mathematical models based on the law of kinetic energy conservation and the rate of change in angular momentum of a spinning rotor. Gyroscope theory still attracts many researchers who continue to discover new properties of gyroscopic devices. In reality, gyroscope effects are more complex and known mathematical models do not accurately reflect the actual motions. Analysis of forces acting on a gyroscope shows that four dynamic components act simultaneously: the centrifugal, inertial and Coriolis forces and the rate of change in angular momentum of the spinning rotor. The spinning rotor generates a rotating plane of centrifugal and Coriols forces that resist the twisting of the spinning rotor with external torque applied. The forced inclination of the spinning rotor generates inertial forces, resulting in precession torque of a gyroscope. The rate of change of the angular momentum creates resisting and precession torques which are not primary one in gyroscope effects. The new mathematical model for the gyroscope motions under the action of the external torque applied can be as base for new gyroscope theory. At the request of the author of the paper, this corrigendum was issued on 24 May 2016 to correct an incomplete Table 1 and errors in Eq. (47) and Eq. (48).

  12. A statistical model for estimation of fish density including correlation in size, space, time and between species from research survey data

    DEFF Research Database (Denmark)

    Nielsen, J. Rasmus; Kristensen, Kasper; Lewy, Peter

    2014-01-01

    Trawl survey data with high spatial and seasonal coverage were analysed using a variant of the Log Gaussian Cox Process (LGCP) statistical model to estimate unbiased relative fish densities. The model estimates correlations between observations according to time, space, and fish size and includes...

  13. The effects of rotator cuff tears, including shoulders without pain, on activities of daily living in the general population.

    Science.gov (United States)

    Nakajima, Daisuke; Yamamoto, Atsushi; Kobayashi, Tsutomu; Osawa, Toshihisa; Shitara, Hitoshi; Ichinose, Tsuyoshi; Takasawa, Eiji; Takagishi, Kenji

    2012-03-01

    Few reports have so far evaluated the possible restrictions of activities of daily living (ADL) in patients with asymptomatic rotator cuff tears (RCTs). The purpose of this study was to examine the effects of RCTs, including shoulders without pain, on ADL in the general population. We performed medical checkups on 462 individuals (924 shoulders). All participants completed a questionnaire regarding their background and medical history. We then assessed their shoulder functions with the Simple Shoulder Test (SST) and performed US (US) examinations of both shoulders to diagnose RCTs. We divided participants into tear and nontear groups and performed statistical analysis to compare total SST scores and each SST item between groups. Furthermore, we performed the same examinations for participants identified as having shoulders without pain. Among participants, those in the tear group showed significantly lower total SST scores than those in the nontear group. After examining each SST item, a significant difference was observed regarding the ability to sleep comfortably and to lift 3.6 kg to shoulder level. In shoulders without pain, the tear group showed significantly lower total SST scores than the nontear group. A significant difference was observed only regarding the ability to lift 3.6 kg to shoulder level. In the general population, ADL were restricted in participants with RCTs; they experienced night pain in the shoulder and muscle weakness during shoulder elevation. Furthermore, participants with RCTs, even if the condition itself did not induce any pain, tended to experience muscle weakness during shoulder elevation, thus resulting in restrictions of ADL.

  14. Biologically based multistage modeling of radiation effects

    Energy Technology Data Exchange (ETDEWEB)

    William Hazelton; Suresh Moolgavkar; E. Georg Luebeck

    2005-08-30

    This past year we have made substantial progress in modeling the contribution of homeostatic regulation to low-dose radiation effects and carcinogenesis. We have worked to refine and apply our multistage carcinogenesis models to explicitly incorporate cell cycle states, simple and complex damage, checkpoint delay, slow and fast repair, differentiation, and apoptosis to study the effects of low-dose ionizing radiation in mouse intestinal crypts, as well as in other tissues. We have one paper accepted for publication in ''Advances in Space Research'', and another manuscript in preparation describing this work. I also wrote a chapter describing our combined cell-cycle and multistage carcinogenesis model that will be published in a book on stochastic carcinogenesis models edited by Wei-Yuan Tan. In addition, we organized and held a workshop on ''Biologically Based Modeling of Human Health Effects of Low dose Ionizing Radiation'', July 28-29, 2005 at Fred Hut