WorldWideScience

Sample records for mnd tiina talvi

  1. Kauplus Mulberry - Oksana Tandit = Mulberry - Oksana Tandit store

    Index Scriptorium Estoniae

    2011-01-01

    Inglise firma Mulberry ja eesti moekunstniku Oksana Tanditi kauplusest Tallinnas Suur-Karja 2. Sisearhitektid Tiina Talvi ja Elo Pärlioja. Loetletud sisearhitektide tehtud töid. Interjööris kasutatud sepised valmistasid Tõnu Narro ja Märt Vaidla

  2. Establishing the UK DNA Bank for motor neuron disease (MND).

    Science.gov (United States)

    Smith, Lucy; Cupid, B C; Dickie, B G M; Al-Chalabi, A; Morrison, K E; Shaw, C E; Shaw, P J

    2015-07-14

    In 2003 the Motor Neurone Disease (MND) Association, together with The Wellcome Trust, funded the creation of a national DNA Bank specific for MND. It was anticipated that the DNA Bank would constitute an important resource to researchers worldwide and significantly increase activity in MND genetic research. The DNA Bank houses over 3000 high quality DNA samples, all of which were donated by people living with MND, family members and non-related controls, accompanied by clinical phenotype data about the patients. Today the primary focus of the UK MND DNA Bank still remains to identify causative and disease modifying factors for this devastating disease.

  3. Naised, kes ei oska võidelda / Tiina Tauraite

    Index Scriptorium Estoniae

    Tauraite, Tiina, 1976-

    2011-01-01

    Toimetuse intervjuu näitleja Tiina Tauraitega Sulev Keeduse filmist "Kirjad Inglile" (Eesti-Soome 2011), stsenaristid Madis Kõiv ja Sulev Keedus, produtsent Kaie-Ene Rääk. Tiina Tauraite - arhivaar Edda osatäitja

  4. Ameerikasse õpetama / Tiina Tuuling

    Index Scriptorium Estoniae

    Tuuling, Tiina

    2007-01-01

    Nõo Reaalgümnaasiumi ja Nõo Põhikooli inglise keele õpetaja Tiina Tuulingu töötamisest õpetajana USAs Pennsylvania osariigis Haverfordi Põhikoolis Fulbrighti õpetajate vahetusprogrammi raames

  5. Professor Tiina Tasmuth Helsingis

    Index Scriptorium Estoniae

    2000-01-01

    Tervisekasvatuse õppetooli professor Tiina Tasmuth osales 11.-14. juunini Helsingis toimunud rahvusvahelise konverentsi "2nd Psycho-Social Impacts of Breast Cancer" töös ning esines ettekandega teemal "Chronic post-treatment symptoms in patients with breast cancer" : [täistekst

  6. Tiina Gilli võluvad nii Ameerika kui ka Eesti / Maire Kõrvel

    Index Scriptorium Estoniae

    Kõrver, Maire, 1961-

    2009-01-01

    Fotograaf Tiina Gillist ja tema lennundusinstruktorist abikaasast James Frederick Gillist, kes elasid USA-s Seattle`is ning 2006. aastast elavad Märjamaa lähedal Rangu külas. James tegeleb maalimisega. Tiina on teinud looduse-, linna- ja lillepilte, vähem portreesid

  7. Fourier transform spectroscopy of MnH and MnD

    Science.gov (United States)

    Balfour, W. J.; Launila, O.; Klynning, L.

    Two infrared band systems, centred near 846 nm and 1060 nm in both MnH and MnD have been rotationally analysed and shown to have a common lower state. The electronic transitions lie within the quintet manifold and are here designated c 5Σ-a 5Σ and b 5Πi-a 5Σ for the 846 and 1060 nm systems, respectively. In the 846 nm system in MnH all 10 main branches have been found in the 0-0 and 1-1 bands, while in MnD the data are complete only for 0-0. Satellite branches have been identified in the 1060 nm system and all spin and Λ-type doublings have been established. The number of assigned 0-0 branches in the 1060 nm system is 35 for MnH and 37 for MnD. Molecular constants have been determined for all three states involved. Λ-doubling diagrams are presented for b 5Πi state with v = 1, 2 levels in MnH and with the v = 2 level in MnD. Local perturbations in c5Σ (v = 1) in MnH are suspected to originate from the v = 3 level of b 5Πi.

  8. Management of respiration in MND/ALS patients: an evidence based review.

    Science.gov (United States)

    Heffernan, Catherine; Jenkinson, Crispin; Holmes, Tricia; Macleod, Heidi; Kinnear, William; Oliver, David; Leigh, Nigel; Ampong, Mary-Ann

    2006-03-01

    This systematic review comprises an objective appraisal of the evidence in regard to the management of respiration in patients with motor neuron disease (MND/ALS). Studies were identified through computerised searches of 32 databases. Internet searches of websites of drug companies and MND/ALS research web sites, 'snow balling' and hand searches were also employed to locate any unpublished study or other 'grey literature' on respiration and MND/ALS. Since management of MND/ALS involves a number of health professionals and care workers, searches were made across multiple disciplines. No time frame was imposed on the search in order to increase the probability of identifying all relevant studies, although there was a final limit of March 2005. Recommendations for patient and carer-based guidelines for the clinical management of respiration for MND/ALS patients are suggested on the basis of qualitative analyses of the available evidence. However, these recommendations are based on current evidence of best practice, which largely comprises observational research and clinical opinion. There is a clear need for further evidence, in particular randomised and non-randomised controlled trials on the effects of non-invasive ventilation and additional larger scale cohort studies on the issues of initial assessment of respiratory symptoms, and management and timing of interventions.

  9. checkCIF/PLATON report Datablock: mnd

    Indian Academy of Sciences (India)

    THIS REPORT IS FOR GUIDANCE ONLY. IF USED AS PART OF A REVIEW PROCEDURE. FOR PUBLICATION, IT SHOULD NOT REPLACE THE EXPERTISE OF AN EXPERIENCED. CRYSTALLOGRAPHIC REFEREE. No syntax errors found. CIF dictionary Interpreting this report. Datablock: mnd. Bond precision:.

  10. Tiina Piisang sai preemia

    Index Scriptorium Estoniae

    2001-01-01

    III rahvusvaheline köitekunstisümpoosion 14.-21. XI Vilniuses. Avati näitus "Raamat". Preemiad: I - Anne Giordani, Prantsusmaa, II - Isabelle Poitras, Kanada, III - Tiina Piisang, ergutuspreemia - Duda Rimantas, Leedu. Eestist osalevad väljapanekul veel Silvi Kalda, Marje Kask, Külli Veelaid, Zhanna Zhuravel, Elin Kard, Piret Männa. Odette Drapeau Kanadast tutvustas kalanaha kasutamisvõimalusi raamatuköitmisel

  11. Guidelines for preclinical animal research in ALS/MND: A consensus meeting.

    Science.gov (United States)

    Ludolph, Albert C; Bendotti, Caterina; Blaugrund, Eran; Chio, Adriano; Greensmith, Linda; Loeffler, Jean-Philippe; Mead, Richard; Niessen, Heiko G; Petri, Susanne; Pradat, Pierre-Francois; Robberecht, Wim; Ruegg, Markus; Schwalenstöcker, Birgit; Stiller, Detlev; van den Berg, Leonard; Vieira, Fernando; von Horsten, Stephan

    2010-01-01

    The development of therapeutics for ALS/MND is largely based on work in experimental animals carrying human SOD mutations. However, translation of apparent therapeutic successes from in vivo to the human disease has proven difficult and a considerable amount of financial resources has been apparently wasted. Standard operating procedures (SOPs) for preclinical animal research in ALS/MND are urgently required. Such SOPs will help to establish SOPs for translational research for other neurological diseases within the next few years. To identify the challenges and to improve the research methodology, the European ALS/MND group held a meeting in 2006 and published guidelines in 2007 (1). A second international conference to improve the guidelines was held in 2009. These second and improved guidelines are dedicated to the memory of Sean F. Scott.

  12. Nagu papa soovitas, nii ka läks - tütar hakkas botaanikuks / Tiina Randlane

    Index Scriptorium Estoniae

    Randlane, Tiina, 1953-

    2012-01-01

    Samblikuteadlase Tiina Randlase lapsepõlvest ning aktiivsest tegevusest Tallinna noorte naturalistide jaamas (hilisemas loodusesõprade majas). Tiina Randlase vanemateks olid Tallinna vabariikliku psühhoneuroloogiahaigla psühhiaatrid Ellen ja Vsevolod Grüntal

  13. Kaardikogud raamatukogunduse kaardile / Tiina Kruup, Katre Riisalu

    Index Scriptorium Estoniae

    Kruup, Tiina

    2010-01-01

    15.-19. juunini 2010 toimus Euroopa Teadusraamatukogude Liidu (LIBER) kaardikoguhoidjate ühenduse 17. konverents. Kes on kaardikoguhoidja, mida kujutab endast kaardikogu ning mida arutati konverentsil - sellest vestlevad Tiina Kruup ja Katre Riisalu RR-i kunstide teabekeskusest

  14. "Meie käisime maailmameistrivõistlustel!" / Tiina Madisson

    Index Scriptorium Estoniae

    Madisson, Tiina

    2012-01-01

    Šveitsis 27.-30. oktoobril toimunud 20. ISPU IPO MMist, kus Eestit esindanud suuršnautser Maximus koos perenaise Tiina Madissoniga saavutasid rahvusvahelise teenistuskoerte eksami (IPO) teises raskusastmes kolmanda koha

  15. Kodundust tuleks õpetada teisiti / Tiina Päeva

    Index Scriptorium Estoniae

    Päeva, Tiina

    2001-01-01

    Tiina Päeva 2000. a. läbi viidud uurimistööst "Eesti noorte kodumajanduslikud oskused ja teadmised - nende tähtsus, allikad ning seotus kodumajanduse õpetamisega", milles huvitas autorit, kuidas suhtuvad Eesti noored poistele kodunduse õpetamisse ning mida Eesti noored kodumajandusest kui õppeainest arvavad

  16. Eramu Suurupis = A House in Suurupi / Tiina Mang

    Index Scriptorium Estoniae

    Mang, Tiina

    2002-01-01

    2002. a. valminud eramu projekteeris Arhitektibüroo Emil Urbel. Arhitektid Emil Urbel ja Indrek Erm, sisearhitekt Tiina Mang, konstruktor Peep Rosenberg. Projekt 2000-2001. 7 ill.: I korruse plaan, sise- ja välisvaated.Emil Urbel (arhitektibüroo).

  17. Õnn - õnnelik juhus? / Maarja Paugus ; interv. Tiina Siimets

    Index Scriptorium Estoniae

    Paugus, Maarja

    2004-01-01

    Küsimusele vastavad abikaasad Vanemuise teatri balletitantsija Maarja Paugus ja näitleja Margus Jaanovits ning muusikaõpetaja Tiina ja üldlaulu- ja tantsupeo rahvamuusikapäeva kunstiline juht Aleksander Sünter

  18. Transition probabilities and dissociation energies of MnH and MnD molecules

    International Nuclear Information System (INIS)

    Nagarajan, K.; Rajamanickam, N.

    1997-01-01

    The Frank-Condon factors (vibrational transition probabilities) and r-centroids have been evaluated by the more reliable numerical integration procedure for the bands of A-X system of MnH and MnD molecules, using a suitable potential. By fitting the Hulburt- Hirschfelder function to the experimental potential curve using correlation coefficient, the dissociation energy for the electronic ground states of MnH and MnD molecules, respectively have been estimated as D 0 0 =251±5 KJ.mol -1 and D 0 0 =312±6 KJ.mol -1 . (authors)

  19. Vtoroi plan vremeni / Tiina Abel ; interv. Nikolai Hrustaljov

    Index Scriptorium Estoniae

    Abel, Tiina, 1951-

    2007-01-01

    Näituse "Metafoor ja müüt. Kirjanduslikud ja ajaloolised motiivid 19. ja 20. sajandi vahetuse Poola kunstis" Kumu kunstimuuseumi kuraatori Tiina Abeliga näituse ettevalmistustööst, poola maalikunstist 19. sajandil, töödest näitusel

  20. From symptom onset to a diagnosis of amyotrophic lateral sclerosis/motor neuron disease (ALS/MND): experiences of people with ALS/MND and family carers - a qualitative study.

    Science.gov (United States)

    O'Brien, Mary R; Whitehead, Bridget; Jack, Barbara A; Mitchell, John Douglas

    2011-03-01

    Our objectives were to explore the personal perspectives of the diagnostic experience for people with ALS/MND and their family carers identifying issues that could impact positively or negatively on these experiences. We conducted a qualitative study with face-to-face interviews to capture experiences from 24 people with ALS/MND and 18 current family carers. Ten former family carers were also interviewed. The diagnostic experience was fraught with difficulties. There was failure to recognize the significance of some symptoms by patients, carers and primary and secondary care health professionals, which ultimately delayed diagnosis. Delivery of the diagnosis was frequently unsatisfactory despite international guidelines on the subject. Immediate post-diagnosis support often compared negatively to that provided for people with cancer. In conclusion, this study has identified a need for a more streamlined and empathetic diagnostic pathway for people with ALS/MND. Improvements to medical curricula are required to increase awareness of the condition and reduce the likelihood of diagnostic delays resulting from a failure to recognize the need for a neurological referral. Greater public awareness of the illness is also needed. Furthermore, delivery of the diagnosis should more closely adhere to established guidelines.

  1. Tiina Mang : vanalinna korter muutus visuaalselt suuremaks / Gitte Hint

    Index Scriptorium Estoniae

    Hint, Gitte

    2003-01-01

    74-ruutmeetrine vanalinna korter, mõeldud kahele inimesele, kellest üks töötab kodus. Enamik mööblist on valmistatud eritellimusel. Sisearhitekt Tiina Mang, tema kommentaarid. Ill.: plaan, 3 värv. vaadet

  2. Assessing social isolation in motor neurone disease: a Rasch analysis of the MND Social Withdrawal Scale.

    Science.gov (United States)

    Gibbons, Chris J; Thornton, Everard W; Ealing, John; Shaw, Pamela J; Talbot, Kevin; Tennant, Alan; Young, Carolyn A

    2013-11-15

    Social withdrawal is described as the condition in which an individual experiences a desire to make social contact, but is unable to satisfy that desire. It is an important issue for patients with motor neurone disease who are likely to experience severe physical impairment. This study aims to reassess the psychometric and scaling properties of the MND Social Withdrawal Scale (MND-SWS) domains and examine the feasibility of a summary scale, by applying scale data to the Rasch model. The MND Social Withdrawal Scale was administered to 298 patients with a diagnosis of MND, alongside the Hospital Anxiety and Depression Scale. The factor structure of the MND Social Withdrawal Scale was assessed using confirmatory factor analysis. Model fit, category threshold analysis, differential item functioning (DIF), dimensionality and local dependency were evaluated. Factor analysis confirmed the suitability of the four-factor solution suggested by the original authors. Mokken scale analysis suggested the removal of item five. Rasch analysis removed a further three items; from the Community (one item) and Emotional (two items) withdrawal subscales. Following item reduction, each scale exhibited excellent fit to the Rasch model. A 14-item Summary scale was shown to fit the Rasch model after subtesting the items into three subtests corresponding to the Community, Family and Emotional subscales, indicating that items from these three subscales could be summed together to create a total measure for social withdrawal. Removal of four items from the Social Withdrawal Scale led to a four factor solution with a 14-item hierarchical Summary scale that were all unidimensional, free for DIF and well fitted to the Rasch model. The scale is reliable and allows clinicians and researchers to measure social withdrawal in MND along a unidimensional construct. © 2013. Published by Elsevier B.V. All rights reserved.

  3. Fourier transform infrared emission spectra of MnH and MnD

    Science.gov (United States)

    Gordon, Iouli E.; Appadoo, Dominique R. T.; Shayesteh, Alireza; Walker, Kaley A.; Bernath, Peter F.

    2005-01-01

    Fourier transform infrared emission spectra of MnH and MnD were observed in the ground X7Σ + electronic state. The vibration-rotation bands from v = 1 → 0 to v = 3 → 2 for MnH and from v = 1 → 0 to v = 4 → 3 for MnD were recorded at an instrumental resolution of 0.0085 cm -1. Spectroscopic constants were determined for each vibrational level and equilibrium constants were found from a Dunham-type fit. The equilibrium vibrational constant ( ωe) for MnH was found to be 1546.84518(65) cm -1, the equilibrium rotational constant ( Be) is 5.6856789(103) cm -1 and the eqilibrium bond distance ( re) was determined to be 1.7308601(47) Å.

  4. Tiina Lokk: "PÖFF võiks olla Eestile väga vinge maineprojekt" / Tiina Lokk ; intervjueerinud Anneli Sihvart

    Index Scriptorium Estoniae

    Lokk, Tiina, 1955-

    2010-01-01

    14. Tallinna Pimedate Ööde Filmifestival toimub 19.11.-5.12.2010. Festivali peakorraldaja Tiina Lokk festivalist, selle sümbolist, PÖFF-i tähendusest maailma filmifestivalide seas, festivalidest Lätis, Leedus ja Venemaal, PÖFF-i rahastamisest, Eesti filmiharidusest. Tutvustatakse mängufilme: Anusha Rizvi "Peepli Live (India, 2010), Jasmila Žbanić'i "Teel" (Bosnia ja Hertsegoviina- Austria- Saksamaa- Horvaatia, 2010), Marianna Kaat'i dokumentaalfilmi "Auk nr 8" (Eesti-Ukraina, 2010)

  5. Uniaxial low cycle fatigue behavior for pre-corroded 16MND5 bainitic steel in simulated pressurized water reactor environment

    Science.gov (United States)

    Chen, Xu; Ren, Bin; Yu, Dunji; Xu, Bin; Zhang, Zhe; Chen, Gang

    2018-06-01

    The effects of uniaxial tension properties and low cycle fatigue behavior of 16MND5 bainitic steel cylinder pre-corroded in simulated pressurized water reactor (PWR) were investigated by fatigue at room temperature in air and immersion test system, scanning electron microscopy (SEM), energy disperse spectroscopy (EDS). The experimental results indicated that the corrosion fatigue lives of 16MND5 specimen were significantly affected by the strain amplitude and simulated PWR environments. The compositions of corrosion products were complexly formed in simulated PWR environments. The porous corrosion surface of pre-corroded materials tended to generate pits as a result of promoting contact area to the fresh metal, which promoted crack initiation. For original materials, the fatigue cracks initiated at inclusions imbedded in the micro-cracks. Moreover, the simulated PWR environments degraded the mechanical properties and low cycle fatigue behavior of 16MND5 specimens remarkably. Pre-corrosion of 16MND5 specimen mainly affected the plastic term of the Coffin-Manson equation.

  6. Aasta e-kursuse konkursil võitis auhinna Tiina Selke

    Index Scriptorium Estoniae

    2007-01-01

    13. märtsil lõppenud konverentsil "e-õpe e-riigis: strateegiad ja tehnoloogiad" kuulutati välja eelmise aasta parimad e-kursuste loojad. Humaniora kategoorias anti auhind ja multimeedia kasutamise eripreemia e-kursuse "Kodály metoodika" autorile, TLÜ muusikaõpetuse metoodika lektorile Tiina Selkele. e-kursuse konkurssi korraldab e-Õppe Arenduskeskus

  7. Tiina Tammetalu näitab oma uusi ja vanu maale / Andry Ervald

    Index Scriptorium Estoniae

    Ervald, Andry

    2010-01-01

    Tiina Tammetalu maalide näitused tantsukooli Noor Ballett galeriis ja Viimsi Püha Jaakobi kirikus. Viimsi Püha Jaakobi kirikus on eksponeeritud religioosne maaliseeria "Exodus" (Vana Testamendi II Moosese raamatu järgi)

  8. Mis saab ESTERMist? / Tiina Soon, Peeter Päll, Ivi Papstel ; interv. Aili Künstler

    Index Scriptorium Estoniae

    Soon, Tiina

    2008-01-01

    Eesti Õiguskeskuse loodud andmebaasist ESTERM. Vastavad EKI terminoloogiaosakonna juhataja Tiina Soon, EKI keelekorraldusosakonna vanemteadur Peeter Päll, Justiitsministeeriumi avalike suhete talituse juhataja Ivi Papstel

  9. Mälu pole ainult meil, vaid ka meie haigustel / Tiina Sarv

    Index Scriptorium Estoniae

    Sarv, Tiina, 1949-

    2007-01-01

    Pärnus toimunud Eesti arstide Astra Zeneca ABC-konverentsi märksõna oli mälu. Konverentsil esinesid professorid Endel Tulving, Alan Altraja ja Anto Raukas, dotsendid Tiina Ristimäe ja Ursel Soomets, kirjandusteadlane Rutt Hinrikus, zooloog Aleksei Turovski ning arstid Anu Ambos ja Riina Kütner

  10. 'All in the same boat'? Patient and carer attitudes to peer support and social comparison in Motor Neurone Disease (MND).

    Science.gov (United States)

    Locock, Louise; Brown, Janice B

    2010-10-01

    This paper explores attitudes to peer support among people with Motor Neurone Disease (MND) and their family carers. It reports findings from a secondary analysis of data from two UK interview studies conducted by the authors. The process of secondary analysis is reported in detail. 48 people with MND and 22 carers were interviewed in 2005-2007. The authors identified narrative extracts on peer support from their own datasets and exchanged them for independent thematic analysis. Subsequent discussion, drawing on literature on support groups and social comparison, led to an exploration of two overarching themes: valuing camaraderie and comparison, and choosing isolation. Findings suggest that social comparison theory is a useful framework for analysing attitudes to MND support groups, but that on its own it is insufficient. 'Valuing camaraderie and comparison' explains how support groups offer practical and social support, as well as beneficial opportunities for social comparison. Seeing others coping well with the condition can provide hope, while downward comparison with those worse off can also make people feel better about their own situation. However, most people are also shocked and saddened by seeing others with the condition. Tension of identity can occur when group membership starts to define the individual as 'a person with MND, rather than the person I am that happens to have MND'. Choosing isolation can be a deliberate defensive strategy, to protect oneself from witnessing one's possible future. Levels of involvement may change over time as people struggle with their changing needs and fears. Copyright © 2010 Elsevier Ltd. All rights reserved.

  11. Eesti talendid välismaale / Juko-Mart Kõlar, Tiina Jokinen, Anu Jaanson... [jt.

    Index Scriptorium Estoniae

    2011-01-01

    Küsimustele muusikute vahendamisest välismaale vastavad MTÜ Eesti Muusika Ekspordi tegevjuht Juko-Mart Kõlar, Estonian Record Productionsi tegevdirektor Tiina Jokinen, sama firma mänedžer Anu Jaanson ja Pille Lille Muusikute Toetusfondi tegevjuht Leelo Lehtla

  12. Loodusõpetuse õppekomplekt IV klassile : (ilmub 2002.a. sügiseks) / Tiina Elvisto

    Index Scriptorium Estoniae

    Elvisto, Tiina, 1957-

    2002-01-01

    Kirjastuselt Avita ilmub 2002.a. sügiseks 4. klassi bioloogia õppekomplekt, autoriteks Mart Kuurme, Vahur Laug ja Tiina Elvisto. Samadelt autoritelt, neljas kaasautor Kadri Maaste, ilmub Avitalt 2002.a. "Loodusõpetuse õpik-tööraamat 2. klassile"

  13. Comments on The Art of Collecting / Katarina Meister, Lylian Meister, Tiina Sarapu ...[jt.

    Index Scriptorium Estoniae

    2013-01-01

    6. Tallinna rakenduskunsti triennaal "Kogumise kunst" satelliitnäituse kuraator Tiina Sarapu, näitusel osalejad Katarina Meister, Lylian Meister, Marit Ilison, Krista Leesi ja Jaanus Samma ning näituse külastaja, maalikunstnik Kaido Ole näitusest ja kogumise kogemusest

  14. The Submillimeter Spectrum of MnH and MnD (X7Σ+)

    Science.gov (United States)

    Halfen, D. T.; Ziurys, L. M.

    2008-01-01

    The submillimeter-wave spectrum of the MnH and MnD radicals in their 7Σ+ ground states has been measured in the laboratory using direct absorption techniques. These species were created in the gas phase by the reaction of manganese vapor, produced in a Broida-type oven, with either H2 or D2 gas in the presence of a DC discharge. The N = 0 → 1 transition of MnH near 339 GHz was recorded, which consisted of multiple hyperfine components arising from both the manganese and hydrogen nuclear spins. The N = 2 → 3 transition of MnD near 517 GHz was measured as well, but in this case only the manganese hyperfine interactions were resolved. Both data sets were analyzed with a Hund's case b Hamiltonian, and rotational, fine structure, magnetic hyperfine, and electric quadrupole constants have been determined for the two manganese species. An examination of the magnetic hyperfine constants shows that MnH is primarily an ionic species, but has more covalent character than MnF. MnH is a good candidate species for astronomical searches with Herschel, particularly toward material associated with luminous blue variable stars.

  15. Characterizations of microstructural evolutions to heating of two 16MND5 alloys

    International Nuclear Information System (INIS)

    Vereecke, B.

    2003-01-01

    The aim of this work is to predict the risks of ruin of power plants from scenario of accidents. For that, we have to know and simulate the behaviour of material at high temperatures (600-1300 C) or more exactly, of materials of analogous composition but of different sources, constituting the vessel of a PWR reactor in 16MND5 steel. Previous studies (Vereecke and al CFM2003) have shown that the vessel steels can present in the temperature range 900-1000 C an important variability of creep behaviour and in particular of damages mechanisms (ductile or intergranular) which can radically change from a steel to another. In order to explain and model the sources of different damages, we have carried out a metallurgical study on two steels of 16MND5 type. For different kinetics of heating, have been studied: the hardnesses, the grain sizes and the thermo-electric power (TEP). This last qualitative physical measurement allows to follow in our case the dissolution of the alloy elements having precipitated, phenomenon which could be at the origin of the differences of the damage mechanisms noticed at high temperature. (O.M.)

  16. Leebe künism ja range tolerants tõid aasta õppejõu auhinna / Tiina Maripuu ; intervjueerinud Merilyn Merisalu

    Index Scriptorium Estoniae

    Maripuu, Tiina

    2012-01-01

    Peale Pärnu kolledži soome keele lektori Tiina Maripuu nimetati TÜ 2012. a. parimateks õppejõududeks Marju Lepajõe usuteaduskonnast, Ivo Leito loodus- ja tehnoloogiateaduskonnast ning Ruth Kalda arstiteaduskonnast

  17. Kahevahel : Kui hajusad on kultuuriruumi piirid? / Anna Verschik, Tiina Kirss, Mikko Lagerspetz ; intervjueerinud Daniele Monticelli, Merle Karro-Kalberg

    Index Scriptorium Estoniae

    Verschik, Anna, 1968-

    2015-01-01

    Kultuurist, kultuuriruumist, kultuuris olemisest ja sealt pärinemisest arutlevad TLÜ professori Daniele Monticelli eestvõttel TLÜ professorid Anna Verschik ja Tiina Kirss ning Turu Åbo Akadeemia professor Mikko Lagerspetz

  18. Brittle and ductile rupture of 16MND5 steel. Irradiation effect

    International Nuclear Information System (INIS)

    Al Mundheri, M.; Soulat, P.; Pineau, A.

    1986-06-01

    Toughness tests have been made on 16MND5 steel (A508Cl3 steel) - before and after irradiation at 290 0 C (3.10 19 n/cm 2 , E > 1 MeV). It is shown that toughness is lowered following the irradiation and that it is a decreasing function of the thickness of the test pieces. In parallel, tests on three geometries of entailed specimens, prepared in the non-irradiated material, have been made at different temperatures to apply the methodology of local approach of ductile-brittle rupture [fr

  19. Microstructural influence on the local behaviour of 16MND5 steel

    International Nuclear Information System (INIS)

    Sekfali, S.

    2004-06-01

    16MND5 Steel or A508 Cl3 is used for manufacture by forging of nuclear reactor vessels. This material presents a good compromise in term of tenacity and yield stress, its microstructure is mainly bainitic tempered. Because of the chemical composition local variation and process of development, this material presents microstructural heterogeneities which can locally modify the properties of damage. In particular, some zones present a martensitic microstructure. The goal of this thesis is to bring some explanations on the influence of the microstructure; more particularly, size of the crystallographic entities and their spatial distribution on the local behaviour of 16MND5 steel. Two microstructures were elaborated for this purpose, a tempered bainitic microstructure and a tempered martensitic microstructure. An experimental characterization was carried out on the two microstructures in order to determine morphology, spatial distribution of the crystallographic orientations and tensile behaviour. A deposit of micro grid was carried out on tensile specimens to determine the experimental deformation field on a beforehand EBSD analyzed zone. The determination of the tensile behaviour allowed the identification of a multi crystalline behaviour law by a reverse method using the density of dislocation on each system of slip. This behaviour law was used in simulations with a finite element method to simulate the local mechanical field of the two microstructures and to compare with the obtained experimental deformation fields. It results, a good adequacy between simulations and experiments and the description of the influence of the neighbor grain's orientation on the local behaviour. (author)

  20. Guidelines in motor neurone disease (MND)/amyotrophic lateral sclerosis (ALS)--from diagnosis to patient care.

    Science.gov (United States)

    Mitchell, J D

    2000-12-01

    This paper reviews the scope of current guidelines in motor neurone disease (MND)/amyotrophic lateral sclerosis (ALS) and examines issues which have arisen in the preparation of these documents. The review concludes with an evaluation of the impact of the guidelines which have been produced to date and looks towards potential future developments in this area.

  1. Guidelines in motor neurone disease (MND)/amyotrophic lateral sclerosis (ALS) - from diagnosis to patient care.

    Science.gov (United States)

    Mitchell, J D

    2000-12-01

    This paper reviews the scope of current guidelines in motor neurone disease (MND)/amyotrophic lateral sclerosis (ALS) and examines issues which have arisen in the preparation of these documents. The review concludes with an evaluation of the impact of the guidelines which have been produced to date and looks towards potential future developments in this area.

  2. Olympic Casino - meelelahutustööstus, kus kehtib sõjaväekord / Tiina Drui ; interv. Taivo Paju

    Index Scriptorium Estoniae

    Drui, Tiina

    2003-01-01

    Olympic Casino personalijuht Tiina Drui ettevõtte personalipoliitikast, töötajate värbamisest ja koolitamisest. Lisad: Olympic Casino põhimõtted; Küsimused, mille abil mõõta töökoha kvaliteeti. Vt. samas: Olympic Casino - 10 aastat täis

  3. Diffusion-bonded 16MND5-Inconel 690-316LN junction: elaboration and process residual stresses modeling

    International Nuclear Information System (INIS)

    Martinez, Michael

    1999-01-01

    The objective of this research thesis is, on the one hand, to elaborate and to characterise a bonded junction of 16MND5 and 316LN steels, and, on the other hand, to develop a simulation tool for the prediction of microstructures after bonding, as well as residual stresses related to this process. The author first reports the study of the use of diffusion bonding by hot isostatic pressing (HIP diffusion bonding) for the bonding of 16MND5 (steel used in French PWR vessel) and 316LN (austenitic stainless steel used in piping), in order to obtain junctions adapted to a use within PWRs. In this case, the use of an Inconel insert material appeared to be necessary to avoid stainless steel carburization. Thus, inserts in Inconel 600 and 690 have been tested. The objective has then been to develop a realistic calculation of residual stresses in this assembly. These stresses are stimulated by quenching. The author notably studied the simulation of temperature dependent phase transformations, and stress induced phase transformations. An existing model is validated and applied to HIP and quenching cycles. The last part reports the calculation of residual stresses by simulation of the mechanical response of the three-component material cooled from 900 C to room temperature and thus submitted to a loading of thermal origin (dilatation) and metallurgical origin (phase transformations in the 16MND5). The effect of carbon diffusion on mechanical properties has also been taken into account. The author discusses problems faced by existing models, and explains the choice of conventional macro-mechanical models. The three materials are supposed to have a plastic-viscoplastic behaviour with isotropic and kinematic strain hardening, and this behaviour is identified between 20 and 900 C [fr

  4. Withdrawal of ventilation at the patient's request in MND: a retrospective exploration of the ethical and legal issues that have arisen for doctors in the UK.

    Science.gov (United States)

    Phelps, Kay; Regen, Emma; Oliver, David; McDermott, Chris; Faull, Christina

    2017-06-01

    Ventilatory support has benefits including prolonging survival for respiratory failure in motor neurone disease (MND). At some point some patients may wish to stop the intervention. The National Institute of Health and Care Excellence (NICE) guidance recommends research is needed on ventilation withdrawal. There is little literature focusing on the issues doctors encounter when withdrawing ventilation at the request of a patient. To identify and explore with doctors the ethical and legal issues that they had encountered in the withdrawal of ventilation at the request of a patient with MND. A retrospective thematic analysis of interviews of 24 doctors (including palliative care, respiratory, neurology and general practice) regarding their experiences with withdrawal of ventilation support from patients with MND. Respondents found withdrawal of ventilation at the request of patients with MND to pose legal, ethical and moral challenges in five themes: ethical and legal rights to withdrawal from treatment; discussions with family; discussions with colleagues; experiences of legal advice; issues contributing to ethical complexity. Though clear about the legality of withdrawal of treatment in theory, the practice led to ethical and moral uncertainty and mixed feelings. Many respondents had experienced negative reactions from other healthcare professionals when these colleagues were unclear of the distinction between palliation of symptoms, withdrawal of treatment and assisted death. Legal, ethical and practical guidance is needed for professionals who support a patient with MND who wishes to withdraw from ventilation. Open discussion of the ethical challenges is needed as well as education and support for professionals. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  5. Tiina Tammetalu : Eesti maastikud, personifitseeritud, dokumenteeritud = Estonian landscapes, personified, documented / Andreas Trossek

    Index Scriptorium Estoniae

    Trossek, Andreas, 1980-

    2007-01-01

    Maalikunstnik Tiina Tammetalu käsitluses on Eesti maastik dokument, mida ta oma lõuenditel seeriapäraselt rekonstrueerib. 1980-ndate õpiaja maalides kandvaks muutunud kehaesteetika on kunstniku viinud läbi 90-ndate erinevate dokumentaalsete/feministlike näituseprojektide ja kolmemõõtmeliste installatsioonide ideeni, et maastik on kui kunstniku identiteet, on kui keha, on kui mälu. Viimaste aastate töödes aimub kogu seda "eestlaslikku" valulikku ajalootunnetust, need on otsekui retooriliseks vastuseks paljude jaoks korduvale küsimusele - kust oled sa tulnud?

  6. Prof. Tiina Kirsi raamatuesitlus Toronto Ülikoolis : uus ingliskeelne raamat eesti naiste elulugudest / Eda Sepp ; fotod: Eda Sepp

    Index Scriptorium Estoniae

    Sepp, Eda

    2004-01-01

    20. mail 2004 toimus Toronto Ülikooli Eesti Õppetooli juures Tiina Ann Kirsi toimetatud ja Tartu Ülikooli väljaandena 2004. a. ilmunud raamatu "She who remembers survives : interpreting Estonian women's post-soviet life stories" esitlus, kus toimetaja andis põhjaliku ülevaate teose olemusest ning eesmärkidest

  7. Tartu Ülikooli 86. aastapäeva tähistamine Torontos : "Põhjamaine järjekindlus ja hiinlase kannatus" / Tiina Ann Kirss ; fotod: V. Sarapuu

    Index Scriptorium Estoniae

    Kirss, Tiina, 1957-

    2005-01-01

    aktusega Tartu Collegéis 27. novembril 2005. Ülikooli rektor Jaak Aaviksoo analüüsis oma kõnes TÜ arenguvõimalusi ja päevamuresid, Tiina Kirss esitas sissevaate ülikooli ajalukku, muusikalises osas esinesid Kaili ja Riho Maimets

  8. Euroopa Sotsiaalfondi vahendid Eesti noortekeskustes - kasutus, tulemused ja mõju noortekeskustele ning ühiskonnale / Heidi Paabort ; kommenteerinud Kerli Kõiv, Tiina Sinijärv, Aire Pruus

    Index Scriptorium Estoniae

    Paabort, Heidi

    2013-01-01

    ESFi programmide tulemusel toimunud muutusi noorsootöös kommenteerivad Rõuge vallavalitsuse noorsootöö spetsialist Kerli Kõiv, Keila ANK ja Keila Noortekeskuse juhataja Tiina Sinijärv ja Nursi noorsootöös osaleja Aire Pruus

  9. Loode : teoloogiline mõtisklus õigeusu Kiriku pärimuse vaimus / Eesti Apostlik-Õigeusu Kiriku metropoliit,1940- Stefanus ; tõlk. Tiina Niitvägi-Hellamaa

    Index Scriptorium Estoniae

    Stefanus, Eesti Apostlik-Õigeusu Kiriku metropoliit, 1940-

    2008-01-01

    Õigeusu kiriku seisukohtadest inimloote olemuse ja õiguste küsimuste kohta. Lisatud Ateena peapiiskopi ülipühitsetud Kristoduluse tekst ajakirjast Timitkon aphieroma is ton Mitropolitin Kaissarianis Georgion loc. cit., lk. 167-171, tõlk. Tiina Niitvägi-Hellamaa

  10. Stress distribution in the 16MND5 bainitic steel. Experimental analysis and polycrystalline modelling

    International Nuclear Information System (INIS)

    Pesci, R.; Inal, K.; Berveiller, M.; Masson, R.

    2003-01-01

    The 16MND5 bainitic steel being a two-phase material (ferrite/cementite), the X-Ray Diffraction (XRD) is the most efficient tool to determine the stress states into the ferritic phase (sin 2 ψ method). The latter, coupled to the observations realized during tensile tests (specimen surface and facies), have permitted to establish criteria to describe the behavior and the damaging processes of the material on a crystallographic scale, in the lower part of the ductile-to-brittle transition region and at lower temperatures [-196 deg. C;-60 deg. C]. During the loading, the damage is observed with a Scanning Electron Microscope, while the internal stresses are determined by XRD: the stress states are less important in ferrite than in bainite (macroscopic stress), the difference not exceeding 150 MPa. A multi-scale polycrystalline model is developed concurrently with the experimental measurements: a Mori-Tanaka formulation is used to describe the elastoplastic behavior of a ferritic single crystal reinforced by cementite precipitates, while the transition to the polycrystal is achieved by a self-consistent approach. The developed modeling takes into account the temperature effects on the stress states in each phase and includes a cleavage criterion (critical value of the stress normal to [100] planes), which expresses the damage of the material: thus, it enables to predict the actual experimental behavior of the 16MND5 steel in relation to temperature, and to take into account the failure process which is fragile from -120 deg. C. Besides, it is also possible to calculate the strains of the diffracting planes, which can be compared to those measured by XRD: this enables to evaluate the heterogeneity of the strains for each crystallographic orientation. (authors)

  11. President Obama visiidi eduka kommunikatsiooni tagas põhjalik ettevalmistus / Mariann Sudakov, Tiina Ansip, Ainar Ruussaar ...[jt.] ; intervjueerinud Kertu Kärk

    Index Scriptorium Estoniae

    2014-01-01

    Eestit 3. septembril 2014 külastanud USA president Barack Obama visiidi kommunikatsioonist ja planeerimisest räägivad välisministeeriumi pressiosakonna nimel pressispetsialist Mariann Sudakov, valitsuse kommunikatsioonibüroo esindaja, valitsuse meedianõunik valitsuskommunikatsiooni direktori ülesannetes Tiina Ansip, ERR-i juhatuse liige ja ajakirjanik Ainar Ruussaar, Vabariigi Presidendi avalike suhete nõunik Toomas Sildam ning USA saatkonna pressi- ja kultuuriatašee Bradley Hurst

  12. Influence of metallurgical phase transformation on crack propagation of 15-5PH stainless steel and 16MND5 low carbon steel

    International Nuclear Information System (INIS)

    Liu, J.

    2012-01-01

    This study focuses on the effects of phase transformations on crack propagation. We want to understand the changes of fracture toughness during welding. In this work, fracture toughness is expressed by J-integral. There are many experimental methods to obtain the critical toughness JIC but they are impractical for our investigation during phase transformation. That is the reason why we have proposed a method coupling mechanical tests, digital image correlation and finite element simulation. The fracture tests are implemented on pre-cracked single edge notched plate sample which is easy for machining and heat conduct during phase transformation. The tests are conducted at different temperatures until rupture. Digital image correlation gives us the displacement information on every sample. Each test is then simulated by finite element where the fracture toughness is evaluated by the method G-Theta at the crack propagation starting moment found by potential drop method and digital image correlation technical. Two materials have been studied, 15Cr-5Ni martensitic precipitation hardening stainless steel and 16MND5 ferritic low carbon steel. For these two materials, different test temperatures were chosen before, during and after phase transformation for testing and failure characterization of the mechanical behavior. Investigation result shows that metallurgical phase transformation has an influence on fracture toughness and further crack propagation. For 15-5PH, the result of J1C shows that the as received 15-5PH has higher fracture toughness than the one at 200 C. The toughness is also higher than the original material after one cycle heat treatment probably due to some residual austenite. Meanwhile, pure austenite 15-5PH at 200 C has higher fracture toughness than pure martensitic 15-5PH at 200 C. For 16MND5, the result also proves that the phase transformation affects fracture toughness. The as received material has bigger J1C than the situation where it was heated

  13. The synthesis and crystal structures of the first rare-earth alkaline-earth selenite chlorides MNd10(SeO3)12Cl8 (M=Ca and Sr)

    International Nuclear Information System (INIS)

    Berdonosov, P.S.; Olenev, A.V.; Dolgikh, V.A.; Lightfoot, P.

    2007-01-01

    Two new alkaline-earth Nd selenite chlorides MNd 10 (SeO 3 ) 12 Cl 8 (M=Ca, Sr) were obtained using crystal growth from alkaline-earth chloride melts in quartz tubes. These new compounds crystallize in the orthorhombic system in space group C cca (no. 68). The compounds were studied by energy dispersive X-ray spectroscopy (EDX) and X-ray diffraction. It was shown that both compounds adopt the same structure type, constructed by complex [M 11 (SeO 3 ) 12 ] 8+ slabs separated by chloride anion layers perpendicular to the longest cell parameter. The SeO 3 groups show a pyramidal shape and may be described as SeO 3 E tetrahedra. Such SeO 3 groups decorate the Nd-O skeletons forming the [M 11 (SeO 3 ) 12 ] 8+ slabs. - Graphical abstract: Two new alkaline-earth Nd selenite chlorides MNd 10 (SeO 3 ) 12 Cl 8 (M=Ca, Sr) were synthesized. These structures are constructed by [M 11 (SeO 3 ) 12 ] 8+ slabs separated by chloride anion layers

  14. Microstructure and Ductility-Dip Cracking Susceptibility of Circumferential Multipass Dissimilar Weld Between 20MND5 and Z2CND18-12NS with Ni-Base Filler Metal 52

    Science.gov (United States)

    Qin, Renyao; Duan, Zhaoling; He, Guo

    2013-10-01

    The large circumferential multipass dissimilar weld between 20MND5 steel and Z2CND18-12NS stainless steel welded with FM52 filler material was investigated in terms of the diluted composition, the grain boundary precipitation, and the ductility-dip cracking (DDC) susceptibility of the weld. The diluted composition of the weld is composed of 37 to 47 pct Ni, 21 to 24 pct Cr, and 28 to 40 pct Fe, which are inhomogeneous along the depth and over the width of the deep weld. The carbon content has a distribution in the region of the surface weld from a high level (~0.20 pct) in the zone near 20MND5 steel to a normal level (~0.03 pct) in the zone near Z2CND18-12NS stainless steel. The carbon distribution is corresponding to the grain boundary carbides. The minimum threshold strains for DDC occur in the temperature range of 1223 K to 1323 K (950 °C to 1050 °C), which are 0.5, 0.35, and 0.4 pct for the root weld, middle region, and the surface weld, respectively. The dissimilar weld has the largest susceptibility to the DDC compared to the filler metal 52 and the Inconel 690.

  15. Milline kevad tuleb? / Kätlin Karik

    Index Scriptorium Estoniae

    Karik, Kätlin

    2016-01-01

    Oma kevadisi rõivakollektsioone tutvustavad Ülle Pohjanheimo, Ivo Nikkolo, Althea/Thea Pilvet, Roberta Einer, Monton, Aldo Järvsoo, Ketlin Bachmann, Riina Põldroos, Kriss Soonik, Tiina by Tiina/Tiina Talumees, Iris Janvier

  16. Investigation of the high temperature behaviour of an unsteady crack growth in 16MND5 steel and application to the calculation of vessel bottom failure in case of severe accident

    International Nuclear Information System (INIS)

    Tardif, N.

    2009-01-01

    This research thesis deals with the prediction of the failure of a pressurized water reactor under an accidental thermo-mechanical loading. This study is based on tests performed on an instrumented mock-up and on the comparison of experimental results obtained on two different 16MND15 steel grades with numerical simulation results. The test model is a tube submitted to tension and inner pressure. Temperatures, strains and pressure are measured and images are acquired by two rapid digital cameras and an infrared camera. Crack initiation and propagation conditions are acquired. Simulations are performed using finite elements and the ABAQUS code. Crack initiation and growth are modelled by a cohesive area method. Strain rates are also studied

  17. Guidelines for the preclinical in vivo evaluation of pharmacological active drugs for ALS/MND: report on the 142nd ENMC international workshop.

    Science.gov (United States)

    Ludolph, Albert C; Bendotti, Caterina; Blaugrund, Eran; Hengerer, Bastian; Löffler, Jean-Philippe; Martin, Joanne; Meininger, Vincent; Meyer, Thomas; Moussaoui, Saliha; Robberecht, Wim; Scott, Sean; Silani, Vincenzo; Van Den Berg, Leonard H

    2007-08-01

    A transgenic animal model for anterior horn cell loss was established in 1994. This model is based on the insertion of a high copy number of disease-causing human Cu/Zn SOD mutations into the intact mouse genome. It serves to establish hypotheses for the pathogenesis of anterior horn cell death, but also to test potential pharmacological approaches to therapy in human ALS. Today, more than 100 -- published and unpublished -- compounds have been tested in this animal model, a large part of them being reported as successful. However, it proved to be difficult to translate these therapeutic successes in the animal model into human trials. Also, a number of disease-modifying strategies were difficult to reproduce, even by the same group. On the other hand, the step from mice to men means a huge investment for the sponsors of clinical trials and the scientific community. Therefore, establishment of standard methods for drug testing in ALS models is mandatory. In this workshop, clinical and preclinical researchers established in the field of ALS/MND met in Holland in March 2006 in order to establish guidelines for the community for drug testing in mouse models.

  18. Puuduv paradigma : klassitsism : koopia / Linnar Priimägi

    Index Scriptorium Estoniae

    Priimägi, Linnar, 1954-

    2005-01-01

    Näitusekataloog-artiklikogumikust "Meistriteoste lummus : koopia Eestis XIX sajandil : näitus Kadrioru Kunstimuuseumis" (Tallinn : Eesti Kunstimuuseum, 2005), Peeter Lauritsa kujundusest, Tiina Abeli ja Tiina-Mall Kreemi artiklitest

  19. Tunnustame tõenduspõhise õendusabi edendajaid / Ester Öpik, Ilme Aro

    Index Scriptorium Estoniae

    Öpik, Ester

    2014-01-01

    Tunnustati meditsiiniõdesid Tiina Freimanni, Reet Urbanit, Marika Asbergi, Tiina Tõemetsa, Kersti Viitkarit ja Ireen Bruusi Eesti Õdede Liidu poolt 2011. aastani kaitstud õendusteaduslike uurimistööde eest

  20. Ilusalt lugemine ehk võistulausumine Linnateatris / Riin Aljas

    Index Scriptorium Estoniae

    Aljas, Riin

    2008-01-01

    Vabariiklikust etlejate konkursist. 4.-6. klasside arvestuses võitis Grand Prix' Markkus Pulk, laureaatideks tulid Maria Pihlak, Kenneth Norden ja Laura Elisabeth Konsand. 7.-9. klasside arvestuses võitis Grand Prix' Anna Talvi, laureaatideks tulid Liisa Saaremäel, Karmen Kozma, Riko Osila. 10.-12. klasside arvestuses võitis Grand Prix' Doris Tääker, laureaatideks tulid Jörgen Liik, Virgo Ernits ja Ilja Massalov

  1. A micro-mechanical analysis and an experimental characterisation of the behavior and the damaging processes of a 16MND5 pressure vessel steel at low temperature; Etude micromecanique et caracterisation experimentale du comportement et de l'endommagement de l'acier de cuve 16MND5 a basses temperatures

    Energy Technology Data Exchange (ETDEWEB)

    Pesci, R

    2004-06-15

    As part of an important experimental and numerical research program launched by Electricite De France on the 16MND5 pressure vessel steel, sequenced and in-situ tensile tests are realized at low temperatures [-196 C;-60 C]. They enable to associate the observation of specimens, the complete cartography of which has been made with a scanning electron microscope (damaging processes, initiation and propagation of microcracks), with the stress states determined by X-ray diffraction, in order to establish relevant criteria. All these measurements enable to supply a two-scale polycrystalline modeling of behavior and damage (Mori-Tanaka/self-consistent) which is developed concurrently with the experimental characterization. This model proves to be a very efficient one, since it correctly reproduces the influence of temperature experimentally defined: the stress state in ferrite remains less important than in bainite (the difference never exceeds 150 MPa), whereas it is much higher in cementite. The heterogeneity of strains and stresses for each crystallographic orientation is well rendered; so is cleavage fracture normal to the {l_brace}100{r_brace} planes in ferrite (planes identified by electron back scattered diffraction during an in-situ tensile test at -150 C), which occurs sooner when temperature decreases, for a constant stress of about 700 MPa in this phase. (author)

  2. "Anything that makes life's journey better." Exploring the use of digital technology by people living with motor neurone disease.

    Science.gov (United States)

    Hobson, Esther V; Fazal, Saima; Shaw, Pamela J; McDermott, Christopher J

    2017-08-01

    Our aim was to explore the attitudes of those living with motor neuron disease towards digital technology. Postal and online questionnaires surveyed 83 people with MND (pwMND) and 54 friends and family members (fMND). Five pwMND and five fMND underwent semi-structured interviews. 82% of pwMND and 87% of fMND use technology every day with iPads and laptops being the devices most commonly used. pwMND used technology to help them continue to participate in everyday activities such as socialising, entertainment and accessing the internet. The internet provided peer support and information about MND but information could be distressing or unreliable. Participants preferred information from professionals and official organisations. Participants were generally supportive of using of technology to access medical care. Barriers to technology, such as lack of digital literacy skills and upper limb dysfunction, and potential solutions were identified. More challenging barriers included language and cognitive difficulties, and the fear of becoming dependent on technology. Addressing the barriers identified in this research could help pwMND access technology. However, as healthcare delivery becomes more reliant on digital technology, care should be taken to ensure that those who are unable or unwilling to use technology continue to have their needs met in alternative ways.

  3. Heavy metals in locus ceruleus and motor neurons in motor neuron disease.

    Science.gov (United States)

    Pamphlett, Roger; Kum Jew, Stephen

    2013-12-12

    The causes of sporadic amyotrophic lateral sclerosis (SALS) and other types of motor neuron disease (MND) remain largely unknown. Heavy metals have long been implicated in MND, and it has recently been shown that inorganic mercury selectively enters human locus ceruleus (LC) and motor neurons. We therefore used silver nitrate autometallography (AMG) to look for AMG-stainable heavy metals (inorganic mercury and bismuth) in LC and motor neurons of 24 patients with MND (18 with SALS and 6 with familial MND) and in the LC of 24 controls. Heavy metals in neurons were found in significantly more MND patients than in controls when comparing: (1) the presence of any versus no heavy metal-containing LC neurons (MND 88%, controls 42%), (2) the median percentage of heavy metal-containing LC neurons (MND 9.5%, control 0.0%), and (3) numbers of individuals with heavy metal-containing LC neurons in the upper half of the percentage range (MND 75%, controls 25%). In MND patients, 67% of remaining spinal motor neurons contained heavy metals; smaller percentages were found in hypoglossal, nucleus ambiguus and oculomotor neurons, but none in cortical motor neurons. The majority of MND patients had heavy metals in both LC and spinal motor neurons. No glia or other neurons, including neuromelanin-containing neurons of the substantia nigra, contained stainable heavy metals. Uptake of heavy metals by LC and lower motor neurons appears to be fairly common in humans, though heavy metal staining in the LC, most likely due to inorganic mercury, was seen significantly more often in MND patients than in controls. The LC innervates many cell types that are affected in MND, and it is possible that MND is triggered by toxicant-induced interactions between LC and motor neurons.

  4. Heavy metals in locus ceruleus and motor neurons in motor neuron disease

    Science.gov (United States)

    2013-01-01

    Background The causes of sporadic amyotrophic lateral sclerosis (SALS) and other types of motor neuron disease (MND) remain largely unknown. Heavy metals have long been implicated in MND, and it has recently been shown that inorganic mercury selectively enters human locus ceruleus (LC) and motor neurons. We therefore used silver nitrate autometallography (AMG) to look for AMG-stainable heavy metals (inorganic mercury and bismuth) in LC and motor neurons of 24 patients with MND (18 with SALS and 6 with familial MND) and in the LC of 24 controls. Results Heavy metals in neurons were found in significantly more MND patients than in controls when comparing: (1) the presence of any versus no heavy metal-containing LC neurons (MND 88%, controls 42%), (2) the median percentage of heavy metal-containing LC neurons (MND 9.5%, control 0.0%), and (3) numbers of individuals with heavy metal-containing LC neurons in the upper half of the percentage range (MND 75%, controls 25%). In MND patients, 67% of remaining spinal motor neurons contained heavy metals; smaller percentages were found in hypoglossal, nucleus ambiguus and oculomotor neurons, but none in cortical motor neurons. The majority of MND patients had heavy metals in both LC and spinal motor neurons. No glia or other neurons, including neuromelanin-containing neurons of the substantia nigra, contained stainable heavy metals. Conclusions Uptake of heavy metals by LC and lower motor neurons appears to be fairly common in humans, though heavy metal staining in the LC, most likely due to inorganic mercury, was seen significantly more often in MND patients than in controls. The LC innervates many cell types that are affected in MND, and it is possible that MND is triggered by toxicant-induced interactions between LC and motor neurons. PMID:24330485

  5. Amygdala TDP-43 Pathology in Frontotemporal Lobar Degeneration and Motor Neuron Disease.

    Science.gov (United States)

    Takeda, Takahiro; Seilhean, Danielle; Le Ber, Isabelle; Millecamps, Stéphanie; Sazdovitch, Véronique; Kitagawa, Kazuo; Uchihara, Toshiki; Duyckaerts, Charles

    2017-09-01

    TDP-43-positive inclusions are present in the amygdala in frontotemporal lobar degeneration (FTLD) and motor neuron disease (MND) including amyotrophic lateral sclerosis. Behavioral abnormalities, one of the chief symptoms of FTLD, could be, at least partly, related to amygdala pathology. We examined TDP-43 inclusions in the amygdala of patients with sporadic FTLD/MND (sFTLD/MND), FTLD/MND with mutation of the C9ORF72 (FTLD/MND-C9) and FTLD with mutation of the progranulin (FTLD-GRN). TDP-43 inclusions were common in each one of these subtypes, which can otherwise be distinguished on topographical and genetic grounds. Conventional and immunological stainings were performed and we quantified the numerical density of inclusions on a regional basis. TDP-43 inclusions in amygdala could be seen in 10 out of 26 sFTLD/MND cases, 5 out of 9 FTLD/MND-C9 cases, and all 4 FTLD-GRN cases. Their numerical density was lower in FTLD/MND-C9 than in sFTLD/MND and FTLD-GRN. TDP-43 inclusions were more numerous in the ventral region of the basolateral nucleus group in all subtypes. This contrast was apparent in sporadic and C9-mutated FTLD/MND, while it was less evident in FTLD-GRN. Such differences in subregional involvement of amygdala may be related to the region-specific neuronal connections that are differentially affected in FTLD/MND and FTLD-GRN. © 2017 American Association of Neuropathologists, Inc. All rights reserved.

  6. Micro-mechanical analysis and modelling of the behavior and brittle fracture of a french 16MND5 steel: role of microstructural heterogeneities; Analyse et modelisation micromecanique du comportement et de la rupture fragile de l'acier 16MND5: prise en compte des heterogeneites microstructurales

    Energy Technology Data Exchange (ETDEWEB)

    Mathieu, J.Ph

    2006-10-15

    Reactor Pressure Vessel is the second containment barrier between nuclear fuel and the environment. Electricite de France's reactors are made with french 16MND5 low-alloyed steel (equ. ASTM A508 Cl.3). Various experimental techniques (scanning electron microscopy, X-ray diffraction...) are set up in order to characterize mechanical heterogeneities inside material microstructure during tensile testing at different low temperatures [-150 C;-60 C]. Heterogeneities can be seen as the effect of both 'polycrystalline' and 'composite' microstructural features. Interphase (until 150 MPa in average between ferritic and bainitic macroscopic stress state) and intra-phase (until 100 MPa in average between ferritic orientations) stress variations are highlighted. Modelling involves micro-mechanical description of plastic glide, mean fields models and realistic three-dimensional aggregates, all put together inside a multi-scale approach. Calibration is done on macroscopic stress-strain curves at different low temperatures, and modelling reproduces experimental stress heterogeneities. This modelling allows to apply a local micro-mechanical fracture criterion for crystallographic cleavage. Deterministic computations of time to fracture for different carbides random selection provide a way to express probability of fracture for the elementary volume. Results are in good agreement with hypothesis made by local approach to fracture. Hence, the main difference is that no dependence to loading nor microstructure features is supposed for probability of fracture on the representative volume: this dependence is naturally introduced by modelling. (author)

  7. Micro-mechanical analysis and modelling of the behavior and brittle fracture of a french 16MND5 steel: role of microstructural heterogeneities

    International Nuclear Information System (INIS)

    Mathieu, J.Ph.

    2006-10-01

    Reactor Pressure Vessel is the second containment barrier between nuclear fuel and the environment. Electricite de France's reactors are made with french 16MND5 low-alloyed steel (equ. ASTM A508 Cl.3). Various experimental techniques (scanning electron microscopy, X-ray diffraction...) are set up in order to characterize mechanical heterogeneities inside material microstructure during tensile testing at different low temperatures [-150 C;-60 C]. Heterogeneities can be seen as the effect of both 'polycrystalline' and 'composite' microstructural features. Interphase (until 150 MPa in average between ferritic and bainitic macroscopic stress state) and intra-phase (until 100 MPa in average between ferritic orientations) stress variations are highlighted. Modelling involves micro-mechanical description of plastic glide, mean fields models and realistic three-dimensional aggregates, all put together inside a multi-scale approach. Calibration is done on macroscopic stress-strain curves at different low temperatures, and modelling reproduces experimental stress heterogeneities. This modelling allows to apply a local micro-mechanical fracture criterion for crystallographic cleavage. Deterministic computations of time to fracture for different carbides random selection provide a way to express probability of fracture for the elementary volume. Results are in good agreement with hypothesis made by local approach to fracture. Hence, the main difference is that no dependence to loading nor microstructure features is supposed for probability of fracture on the representative volume: this dependence is naturally introduced by modelling. (author)

  8. Nonmotor symptoms in patients suffering from motor neuron diseases

    Directory of Open Access Journals (Sweden)

    Rene Günther

    2016-07-01

    Full Text Available Background: The recently postulated disease spreading hypothesis has gained much attention, especially for Parkinson’s disease (PD. The various nonmotor symptoms (NMS in neurodegenerative diseases would be much better explained by this hypothesis than by the degeneration of disease-specific cell populations. Motor neuron disease (MND is primarily known as a group of diseases with a selective loss of motor function. Recent evidence, however, suggests disease spreading into nonmotor brain regions also in MND. The aim of this study was to comprehensively detect NMS in patients suffering from MND.Methods: We used a self-rating questionnaire including 30 different items of gastrointestinal, autonomic, neuropsychiatric and sleep complaints (NMSQuest which is an established tool in PD patients. 90 MND patients were included and compared to 96 controls.Results: In total, MND patients reported significantly higher NMS scores (median: 7 points in comparison to controls (median: 4 points. Dribbling, impaired taste/smelling, impaired swallowing, weight loss, loss of interest, sad/blues, falling and insomnia were significantly more prevalent in MND patients compared to controls. Interestingly excessive sweating was more reported in the MND group. Correlation analysis revealed an increase of total NMS score with disease progression.Conclusions: NMS in MND patients seemed to increase with disease progression which would fit with the recently postulated disease spreading hypothesis. The total NMS score in the MND group significantly exceeded the score for the control group, but only 8 of the 30 single complaints of the NMSQuest were significantly more often reported by MND patients. Dribbling, impaired swallowing, weight loss and falling could primarily be connected to motor neuron degeneration and declared as motor symptoms in MND.

  9. Non-Motor Symptoms in Patients Suffering from Motor Neuron Diseases.

    Science.gov (United States)

    Günther, René; Richter, Nicole; Sauerbier, Anna; Chaudhuri, Kallol Ray; Martinez-Martin, Pablo; Storch, Alexander; Hermann, Andreas

    2016-01-01

    The recently postulated "disease spreading hypothesis" has gained much attention, especially for Parkinson's disease (PD). The various non-motor symptoms (NMS) in neurodegenerative diseases would be much better explained by this hypothesis than by the degeneration of disease-specific cell populations. Motor neuron disease (MND) is primarily known as a group of diseases with a selective loss of motor function. However, recent evidence suggests disease spreading into non-motor brain regions also in MND. The aim of this study was to comprehensively detect NMS in patients suffering from MND. We used a self-rating questionnaire including 30 different items of gastrointestinal, autonomic, neuropsychiatric, and sleep complaints [NMS questionnaire (NMSQuest)], which is an established tool in PD patients. 90 MND patients were included and compared to 96 controls. In total, MND patients reported significantly higher NMS scores (median: 7 points) in comparison to controls (median: 4 points). Dribbling, impaired taste/smelling, impaired swallowing, weight loss, loss of interest, sad/blues, falling, and insomnia were significantly more prevalent in MND patients compared to controls. Interestingly, excessive sweating was more reported in the MND group. Correlation analysis revealed an increase of total NMS score with disease progression. NMS in MND patients seemed to increase with disease progression, which would fit with the recently postulated "disease spreading hypothesis." The total NMS score in the MND group significantly exceeded the score for the control group, but only 8 of the 30 single complaints of the NMSQuest were significantly more often reported by MND patients. Dribbling, impaired swallowing, weight loss, and falling could primarily be connected to motor neuron degeneration and declared as motor symptoms in MND.

  10. Relationship between 3-Methyl-2,4-nonanedione Concentration and Intensity of Light-induced Off-odor in Soy Bean Oil.

    Science.gov (United States)

    Sano, Takashi; Iwahashi, Maiko; Imagi, Jun; Sato, Toshiro; Yamashita, Toshiyuki; Fukusaki, Eiichiro; Bamba, Takeshi

    2016-05-01

    A beany and green off-odor is developed in soy bean oil (SBO) under light-induced oxidative conditions. 3-Methyl-2,4-nonanedione (3-MND) was inferred as the compound responsible for the off-odor. In this study, we designed a simple quantification method for 3-MND in SBO, and evaluated the relationship between the 3-MND concentration and the intensity of the off-odor. 3-MND was analyzed by GC/MS with a thermal desorption unit system. By our method, the 3-MND concentration was found to increase with storage days and the SBO content under light exposure, and there was a high correlation between the measured 3-MND concentration and the intensity of the light-induced off-odor in SBO (R = 0.9586).

  11. Nasta- ja kitkarenkaiden vertailu

    OpenAIRE

    Sairanen, Henri

    2011-01-01

    Suomen talvi-ilmasto asettaa erityisvaatimuksia henkilöautojen renkaille. Jäisillä teillä ajamiseen vaaditaan renkaalta erityisominaisuuksia, jotta sujuva ja turvallinen liikenne on mahdollista. Autoilijat käyvät jatkuvasti keskustelua siitä, kumpi rengas on parempi talviajoon, nastarengas vai kitkarengas. Työni tarkoitus oli koota yhteen eri tutkimuksissa ilmi tullutta tietoa nasta- ja kitkarenkaista ja vertailla renkaiden hyviä ja huonoja puolia. Tämä työ on toteutettu itsenäisesti per...

  12. Hanbok dreams : Korealaisen kansallispuvun inspiroima mallisto

    OpenAIRE

    Turtiainen, Salla-Maarit

    2014-01-01

    Opinnäytetyön aiheena oli malliston suunnittelu korealaisen kansallispuvun, hanbokin, inspiroimana sesongille syksy/talvi 2014–15. Malliston suunnittelun lähtökohtana on käytetty hanbokin kaavaa, mittasuhteita ja yksityiskohtia. Opinnäytetyön tavoitteena oli luoda mallisto joka saisi ihmiset kiinnostumaan tekijän mahdollisen tulevan yrityksen palveluista sekä kehittää tekijän suunnittelu- ja ompelutaitoja. Opinnäytetyössä hankittiin tietoa hanbokista, sen ominaisuuksista ja kaavoituksesta...

  13. The current perception threshold test differentiates categories of mechanical neck disorder.

    Science.gov (United States)

    Uddin, Zakir; MacDermid, Joy C; Galea, Victoria; Gross, Anita R; Pierrynowski, Michael R

    2014-07-01

    Cross-sectional discriminative analysis. To determine whether current perception threshold (CPT) can differentiate between categories of patients with mechanical neck disorders (MNDs). Neck pain is the third most common musculoskeletal disorder and affects a third of all adults each year. It can present as neck pain without musculoskeletal signs, neck pain with musculoskeletal signs but no neurological signs, or neck pain with neurological signs. CPT testing can assess altered sensory perception that may reflect neurological changes. Patients with MNDs (n = 106) were classified into 3 groups, based on a standardized musculoskeletal examination process performed by an experienced physiotherapist who was blinded to CPT scores. The 3 groups were defined as neck pain without musculoskeletal signs (MND I) (n = 60), neck pain with musculoskeletal signs (MND II) (n = 29), and neck pain with neurological signs (MND III) (n = 17). A rapid protocol of CPT testing was performed at 3 frequencies (5, 250, and 2000 Hz), using 3 dermatomal locations on the hand. A 1-way analysis of variance with post hoc comparison and effect sizes was calculated to compare the mean CPT scores between the groups. A binary logistic-regression model was used to predict probability of higher CPT in MND III and to create a receiver-operating-characteristic curve. Mean CPT differed significantly across the 3 MND groups (MND I, 9.7; MND II, 10.6; and MND III, 11.8; Pabnormal CPT in MND III had an estimated 73% sensitivity and 81% specificity; the odds ratio was 11.5 (P = .001) for the differentiation capacity of CPT between MND II and III, with a cutoff of 11. The area under the receiver-operating-characteristic curve was 0.84 (95% confidence interval: 0.72, 0.96; P<.001). CPT testing has moderate discriminatory accuracy, specificity, and sensitivity for classification of MND categories into neck pain with or without neurological signs. J Orthop Sports Phys Ther 2014;44(7):532-540. Epub 10 May 2014

  14. Two Studies on Twitter Networks and Tweet Content in Relation to Amyotrophic Lateral Sclerosis (ALS): Conversation, Information, and 'Diary of a Daily Life'.

    Science.gov (United States)

    Hemsley, Bronwyn; Palmer, Stuart

    2016-01-01

    To date, there is no research examining how adults with Amyotrophic Lateral Sclerosis (ALS) or Motor Neurone Disease (MND) and severe communication disability use Twitter, nor the use of Twitter in relation to ALS/MND beyond its use for fundraising and raising awareness. In this paper we (a) outline a rationale for the use of Twitter as a method of communication and information exchange for adults with ALS/MND, (b) detail multiple qualitative and quantitative methods used to analyse Twitter networks and tweet content in the our studies, and (c) present the results of two studies designed to provide insights on the use of Twitter by an adult with ALS/MND and by #ALS and #MND hashtag communities in Twitter. We will also discuss findings across the studies, implications for health service providers in Twitter, and directions for future Twitter research in relation to ALS/MND.

  15. Imeilus Fine 5

    Index Scriptorium Estoniae

    2017-01-01

    Vaba Lava teatrikeskuse laval esineb Fine 5 oma lavastusega "Imeilus". Tiina Ollesk ja Renee Nõmmik, tantsulavastuse autorid on koreograafid, õppejõud, lavastajad ja kogemustega tantsijad. 29. jaanuaril korraldavad Tiina Ollesk ja Renee Nõmmik Tallinna Ülikoolis kaasaegse liikumismõtlemise töötoa, mis on pühendatud lavastusele "Imeilus"

  16. A Dutch family with autosomal recessively inherited lower motor neuron predominant motor neuron disease due to optineurin mutations

    NARCIS (Netherlands)

    Beeldman, Emma; van der Kooi, Anneke J.; de Visser, Marianne; van Maarle, Merel C.; van Ruissen, Fred; Baas, Frank

    2015-01-01

    Approximately 10% of motor neuron disease (MND) patients report a familial predisposition for MND. Autosomal recessively inherited MND is less common and is most often caused by mutations in the superoxide dismutase 1 (SOD1) gene. In 2010, autosomal recessively inherited mutations in the optineurin

  17. The assessment of minor neurological dysfunction in infancy using the Touwen Infant Neurological Examination : strengths and limitations

    NARCIS (Netherlands)

    Hadders-Algra, Mijna; Heineman, Kirsten R.; Bos, Arend F.; Middelburg, Karin J.

    Aim Little is known of minor neurological dysfunction (MND) in infancy. This study aimed to evaluate the inter-assessor reliability of the assessment of MND with the Touwen Infant Neurological Examination (TINE) and the construct and predictive validity of MND in infancy. Method Inter-assessor

  18. Computational Analysis of Pharyngeal Swallowing Mechanics in Patients with Motor Neuron Disease: A Pilot Investigation.

    Science.gov (United States)

    Garand, K L; Schwertner, Ryan; Chen, Amy; Pearson, William G

    2018-04-01

    Swallowing impairment (dysphagia) is a common sequela in patients with motor neuron disease (MND). The purpose of this retrospective, observational pilot investigation was to characterize how pharyngeal swallowing mechanics are impacted in patients with MND using a comparison with healthy, non-dysphagic control group. Computational analysis of swallowing mechanics (CASM) was used to determine covariate biomechanics of pharyngeal swallowing from videofluoroscopic assessment in 15 patients with MND and 15 age- and sex-matched healthy controls. Canonical variant analysis with post hoc discriminate function analysis (DFA) was performed on coordinate data mapping functional muscle groups underlying pharyngeal swallowing. Differences in swallowing mechanics associated with group (MND; control), motor neuron predominance (upper; lower), onset (bulbar; spinal), and swallow task (thin, pudding) were evaluated and visualized. Pharyngeal swallowing mechanics differed significantly in patients with MND compared with healthy controls (D = 2.01, p mechanics by motor neuron predominance (D = 5.03, p mechanics of patients with MND differ from and are more heterogeneous than healthy controls. These findings suggest patients with MND may compensate reductions in pharyngeal shortening and tongue base retraction by extending the head and neck and increasing hyolaryngeal excursion. This work and further CASM investigations will lead to further insights into development and evaluation of targeted clinical treatments designed to prolong safe and efficient swallowing function in patients with MND.

  19. WAIS Digit Span-Based Indicators of Malingered Neurocognitive Dysfunction: Classification Accuracy in Traumatic Brain Injury

    Science.gov (United States)

    Heinly, Matthew T.; Greve, Kevin W.; Bianchini, Kevin J.; Love, Jeffrey M.; Brennan, Adrianne

    2005-01-01

    The present study determined specificity and sensitivity to malingered neurocognitive dysfunction (MND) in traumatic brain injury (TBI) for several Wechsler Adult Intelligence Scale (WAIS) Digit Span scores. TBI patients (n = 344) were categorized into one of five groups: no incentive, incentive only, suspect, probable MND, and definite MND.…

  20. Olla originaalne ja tähelepandud / Eve Sepp

    Index Scriptorium Estoniae

    Sepp, Eve

    1989-01-01

    Tuntud daamide originaalehetest - tekstiilikunstnik Anna Gerretzi Ülle Kõutsi valmistatud kõrvarõngad, disainer Helle Gansi Katrin Amose loodud rinnanõel, raamatukogudirektrissi Anne Randeli Tiina Käeseli loodud ehted, arhitekt Marka Lõokese Kadri Mälgu loodud komplekt, kunstiteadlase Krista Kodrese Tiina Käeseli loodud komplekt, grimeerija Krista Pärdi abikaasa Rein Metsa loodud ehted

  1. Communications Technology and Motor Neuron Disease: An Australian Survey of People With Motor Neuron Disease.

    Science.gov (United States)

    Mackenzie, Lynette; Bhuta, Prarthna; Rusten, Kim; Devine, Janet; Love, Anna; Waterson, Penny

    2016-01-25

    People with Motor Neuron Disease (MND), of which amyotrophic lateral sclerosis (ALS) is the most common form in adults, typically experience difficulties with communication and disabilities associated with movement. Assistive technology is essential to facilitate everyday activities, promote social support and enhance quality of life. This study aimed to explore the types of mainstream and commonly available communication technology used by people with MND including software and hardware, to identify the levels of confidence and skill that people with MND reported in using technology, to determine perceived barriers to the use of technology for communication, and to investigate the willingness of people with MND to adopt alternative modes of communication. An on-line survey was distributed to members of the New South Wales Motor Neuron Disease Association (MND NSW). Descriptive techniques were used to summarize frequencies of responses and cross tabulate data. Free-text responses to survey items and verbal comments from participants who chose to undertake the survey by telephone were analyzed using thematic analysis. Responses from 79 MND NSW members indicated that 15-21% had difficulty with speaking, writing and/or using a keyboard. Commonly used devices were desktop computers, laptops, tablets and mobile phones. Most participants (84%) were connected to the Internet and used it for email (91%), to find out more about MND (59%), to follow the news (50%) or for on-line shopping (46%). A third of respondents used Skype or its equivalent, but few used this to interact with health professionals. People with MND need greater awareness of technology options to access the most appropriate solutions. The timing for people with MND to make decisions about technology is critical. Health professionals need skills and knowledge about the application of technology to be able to work with people with MND to select the best communication technology options as early as possible

  2. MINOR NEUROLOGICAL DYSFUNCTION AFTER THE ONSET OF PUBERTY - ASSOCIATION WITH PERINATAL EVENTS

    NARCIS (Netherlands)

    SOORANILUNSING, RJ; HADDERSALGRA, M; HUISJES, HJ; TOUWEN, BCL

    In order to study the hypotheses that puberty is related to a decrease of minor neurological dysfunction (MND) and that persisting MND is associated with perinatal factors, two groups (174 normal, 172 MND) of the Groningen Perinatal Project were followed from 12 to 14 years. At 14 years almost all

  3. Multiple nuclear dots and rim-like/membranous IgG isotypes in primary biliary cirrhosis.

    Science.gov (United States)

    Muratori, Paolo; Granito, Alessandro; Ferri, Silvia; Pappas, Georgios; Volta, Umberto; Menichella, Rita; Bianchi, Francesco B; Lenzi, Marco; Muratori, Luigi

    2009-03-01

    Anti nuclear (ANA) immunomorphological patterns such as multiple nuclear dots (MND) and rim-like/membranous (RL/M) are considered highly specific but little sensitive for primary biliary cirrhosis (PBC) diagnosis. To evaluate frequency and clinical significance of MND and RL/M in PBC patients when investigated at the level of immunoglobulin G isotypes. MND and RL/M pattern have been tested in 141 PBC sera and 230 pathological controls using HEp-2 cells as substrate and anti- total IgG and individual IgG subclasses (IgG1, IgG2, IgG3, IgG4) as specific antisera. One hundred and fourteen of 141 (80%) PBC patients had RL/M or MND pattern when IgG subclasses were used as revealing reagents (vs. 34% when anti total IgG were used, p < 0.0001). The prevalent isotype was IgG1 for RL/M, and IgG2 for MND pattern. None of controls was positive. No clinical differences in terms of severity and outcome of disease have been observed in PBC patients positive for MND and RL/M when investigated with IgG isotypes. The research for RL/M and MND pattern at level of IgG isotype determines a wide gain in terms of sensitivity without a loss of specificity. In Italian PBC patients MND and RL/M pattern did not seem to characterize any subgroup of patients with a poorer prognosis.

  4. Soolopartiid Von Krahli katuse all / Kristi Eberhart

    Index Scriptorium Estoniae

    Eberhart, Kristi

    2007-01-01

    Von Krahli Teatri kolmest lavastusest: "Erki ja Tiina" (lavastaja Mart Kangro, tantsivad Erki Laur ja Tiina Tauraite), "Faust" (J. W. Goethe ainetel tekst ja lavastus Taavi Eelmaa, muusika ja laulud Chalice, osades Jarek Kasar ja Rein Pakk), "Hamletid" (William Shakespeare'i ainetel kontseptsiooni, lavastuse, koreograafia, kujunduse, valguse autor Sasha Pepeljajev, video- ja helikunstnik Taavet Jansen. Esitaja Juhan Ulfsak)

  5. Näitleja teeb vahekokkuvõtte ehk Kuidas lavastatakse aega / Katrin Ruus

    Index Scriptorium Estoniae

    Ruus, Katrin

    2006-01-01

    Von Krahli Teatri kolmest lavastusest: "Erki ja Tiina" (lavastaja Mart Kangro, tantsivad Erki Laur ja Tiina Tauraite), "Faust" (J. W. Goethe ainetel tekst ja lavastus Taavi Eelmaa, muusika ja laulud Chalice, osades Jarek Kasar ja Rein Pakk), "Hamletid" (William Shakespeare'i ainetel kontseptsiooni, lavastuse, koreograafia, kujunduse, valguse autor Sasha Pepeljajev, video- ja helikunstnik Taavet Jansen. Esitaja Juhan Ulfsak)

  6. Fotokaameraga Sotšis, Adleris ja Eesti Aiakeses / Riina Mägi

    Index Scriptorium Estoniae

    Mägi, Riina, 1957-

    2009-01-01

    Ants Paju, kunstnik Tiina Sääliku ja Tartus tegutseva Tarbatu segakoori osalemisest 13. septembril Anton-Hansen Tammsaare majamuuseumi taasavamisel Sotši lähedal külas Eesti Aiake (kohtuti ka kohalike eestlaste kooriga Sügis), kontsertidest Sotši sanatooriumides ja orelisaalis. Tiina Säälik avas Jõgeva Kultuurikeskuse galeriis reisipiltidega fotonäituse

  7. Tulge vaatama filme eesti kunstnikest!

    Index Scriptorium Estoniae

    2002-01-01

    24. V Tallinna Kunstihoones filmiprogramm: Peeter Brambat "Müütide mäss", 2002 (Lembit Sarapuust); Rühm+0 (režissöör Meelis Salujärv) "Erki Kasemets", 2002; Mari Sobolev ja Jasper Zoova "The Kids of Rock'n roll", 2000; Tiina Kolgi portreesaade "Õnne sünnipäevaks, Tiina Tammetalu"

  8. 14. II kell 14 esitletakse EKMi Rüütelkonna hoones...

    Index Scriptorium Estoniae

    2005-01-01

    Esitletakse raamatuid "Eesti kunst. 101 teost Eesti kunstimuuseumi kogudest" (autorid: Tiina Abel, Eha Komissarov, Hanno Soans, koostanud T. Abel, E. Komissarov, H. Soans ja Kädi Talvoja, kujundanud Anu Lemsalu), "Kunstnik ja tema kodu. C. T. von Neffi kunstikogu Piira ja Muuga mõisast" (koostanud Tiina Abel, kujundanud Andres Tali) ja Kiwa "Roboti tee on nihe. Salatühik"

  9. Trends in motor neuron disease: association with latitude and air lead levels in Spain.

    Science.gov (United States)

    Santurtún, Ana; Villar, Alejandro; Delgado-Alvarado, Manuel; Riancho, Javier

    2016-08-01

    Motor neuron diseases (MND) are a group of disorders characterized by motor neuron degeneration. Among them, amyotrophic lateral sclerosis (ALS) is by far the most common in adulthood. This paper assesses the trend and geographical pattern in MND incidence in Spain and the possible air lead levels effect on this pathology. To confirm this concept, we performed a retrospective analysis of the deaths due to MND in Spain during 2000 and 2013, determined the geographical differences, and explored the relationship between MND and the air levels of lead. Overall, between 2000 and 2013, 11,355 people died in Spain because of MND. Disease mortality significantly increased in recent years (2007-2013) when compared with the first time of the period. Spearman's rank correlation coefficient also showed a statistically significant positive trend (CC = 0.824, p = 0.0002). Among people over 65 years, mortality rates were higher in Northern provinces. Moreover, we found a significant association of MND mortality with higher air lead levels (CC = 0.457, p = 0.01). Our study confirms that MND mortality is increasing in Spain, with a significant latitude gradient, which suggests an important role of environmental exposures. This ecological study suggests that air lead levels may be implicated in ALS pathogenesis.

  10. Hematological Parameters and the State of Liver Cells of Rats After Oral Administration of Aflatoxin B1 Alone and Together with Nanodiamonds

    Directory of Open Access Journals (Sweden)

    Baron AV

    2010-01-01

    Full Text Available Abstract Hematological parameters and the state of liver cells of rats were examined in vivo after the animals received aflatoxin B1 (AfB1 alone and together with modified nanodiamonds (MND synthesized by detonation. The rats that had received the MND hydrosol had elevated leukocyte levels, mainly due to higher granulocyte counts and somewhat increased monocyte counts compared to control rats. Hematological parameters of the rats that had received AfB1 alone differed from those of the control rats in another way: total white blood cell counts were significantly lower due to the decreased lymphocyte counts. In rats that had consumed AfB1 with the MND hydrosol, changes in hematological parameters were less pronounced than in rats that had consumed either AfB1 or MND. Electron microscopy showed that hepatocytes of the rats that had received the MND hydrosol or AfB1 with the MND hydrosol contained elevated levels of lipid inclusions and lysosomes. Hyperplasia of the smooth endoplasmic reticulum (EPR was revealed in liver specimens of the rats that had received AfB1. Results of the study suggest the conclusion about mutual mitigation of the effects of nanoparticles and the mycotoxin on rats blood and liver cells after AfB1 has adsorbed on MND.

  11. Motor Neurone Disease: Disability Profile and Service Needs in an Australian Cohort

    Science.gov (United States)

    Ng, Louisa; Talman, Paul; Khan, Fary

    2011-01-01

    Motor neurone disease (MND) places considerable burden upon patients and caregivers. This is the first study, which describes the disability profile and healthcare needs for persons with MND (pwMND) in an Australian sample from the perspective of the patients and caregivers to identify current gaps in the knowledge and service provision. A…

  12. Effect of Furan Fatty Acids and 3-Methyl-2,4-nonanedione on Light-Induced Off-Odor in Soybean Oil.

    Science.gov (United States)

    Sano, Takashi; Okabe, Ryo; Iwahashi, Maiko; Imagi, Jun; Sato, Toshiro; Yamashita, Toshiyuki; Fukusaki, Eiichiro; Bamba, Takeshi

    2017-03-15

    Soybean oil is one of the most widely consumed vegetable oils. However, under photooxidative conditions, this oil develops a beany and green off-odor through a mechanism that has not yet been elucidated. Upon photooxidation, 3-methyl-2,4-nonanedione (3-MND) produces a strong aroma. In this study, the effect of furan fatty acids and 3-MND on odor reversion in soybean oil was investigated. Our findings suggest that the observed light-induced off-odor was likely attributable to the furan fatty acids present in the oil through the generation of 3-MND. While 3-MND may not be directly responsible for the development of light-induced off-odor, this compound appears to be involved because off-odor was detected in canola oil samples containing added 3-MND. In addition, in the present work, 3-hydroxy-3-methyl-2,4-nonanedione, which is derived from 3-MND, was identified for the first time in light-exposed soybean oil and shown to be one of the compounds responsible for odor reversion.

  13. Tagasivaade T-le / Riin Kübarsepp

    Index Scriptorium Estoniae

    Kübarsepp, Riin, 1978-

    2002-01-01

    Tiina Tammetalu 2001. a. loodud Imaginaarse Muuseumi projekt "Elav klassika. Rühm T & Guest Stars. Teosed eelmisest sajandist ja tänapäevast" 14. VI-14. VII Haapsalu Linnagaleriis. Väljas on Vilen Künnapu, Raoul Kurvitza, Lilian Mosolaineni, Urmas Muru, Peeter Pere, Tiina Tammetalu, August Künnapu ja Ken Saani maalid ning Mihkel Muti raamat "Elu allikad" (2002)

  14. Cerebrospinal fluid neurofilament light concentration in motor neuron disease and frontotemporal dementia predicts survival.

    Science.gov (United States)

    Skillbäck, Tobias; Mattsson, Niklas; Blennow, Kaj; Zetterberg, Henrik

    2017-08-01

    To aid diagnostics, patient stratification and studies seeking to find treatments for the related diseases motor neuron disease (MND) and frontotemporal dementia (FTD), there is a need to establish a way to assess disease severity and the amount of ongoing neurodegeneration. Previous studies have suggested that cerebrospinal fluid (CSF) neurofilament light (NFL) may serve this purpose. We cross-referenced the Swedish mortality registry with the laboratory database at Sahlgrenska University Hospital to produce a dataset of CSF NFL concentrations and mortality information for 715 MND patients, 87 FTD patients, and 107 healthy controls. Biomarker concentrations were analysed in relation to recorded cause of death and time of death. MND patients had significantly higher CSF NFL concentrations than FTD patients. Both groups had significantly higher concentrations than the healthy controls (mean 709% increase in MND and 307% increase in FTD). Higher concentrations of CSF NFL were associated with shorter survival in both MND and FTD. The results of this study strengthen the notion of CSF NFL as a useful tool for determining disease intensity in MND and FTD patients. Further studies in patient cohorts with clinically subtyped and genetically classified diagnoses are needed.

  15. Genetic epidemiology of motor neuron disease-associated variants in the Scottish population.

    Science.gov (United States)

    Black, Holly A; Leighton, Danielle J; Cleary, Elaine M; Rose, Elaine; Stephenson, Laura; Colville, Shuna; Ross, David; Warner, Jon; Porteous, Mary; Gorrie, George H; Swingler, Robert; Goldstein, David; Harms, Matthew B; Connick, Peter; Pal, Suvankar; Aitman, Timothy J; Chandran, Siddharthan

    2017-03-01

    Genetic understanding of motor neuron disease (MND) has evolved greatly in the past 10 years, including the recent identification of association between MND and variants in TBK1 and NEK1. Our aim was to determine the frequency of pathogenic variants in known MND genes and to assess whether variants in TBK1 and NEK1 contribute to the burden of MND in the Scottish population. SOD1, TARDBP, OPTN, TBK1, and NEK1 were sequenced in 441 cases and 400 controls. In addition to 44 cases known to carry a C9orf72 hexanucleotide repeat expansion, we identified 31 cases and 2 controls that carried a loss-of-function or pathogenic variant. Loss-of-function variants were found in TBK1 in 3 cases and no controls and, separately, in NEK1 in 3 cases and no controls. This study provides an accurate description of the genetic epidemiology of MND in Scotland and provides support for the contribution of both TBK1 and NEK1 to MND susceptibility in the Scottish population. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

  16. Elu koos loodusega / Ell-Maaja Randküla

    Index Scriptorium Estoniae

    Randküla, Ell-Maaja, 1939-2016

    2005-01-01

    Villa Harjumaal Viimsi vallas Miidurannas. Arhitekt Emil Urbel. Sisekujundus: Katrin Vaikla, Argo Vaikla, Tiina Teng, AS Vaikla Disain. Villa pälvis Eesti Sisearhitektide Liidu 2004. a. aastapreemia. Argo ja Katrin Vaiklast, AS Vaikla Disain tähtsamad tööd. Tiina Tengist, tema erialasest tegevusest. Liis Lindverest, tema tähtsamad tööd. Ill.: 3 plaani, 11 värv. vaadet

  17. Mn-doped near-infrared quantum dots as multimodal targeted probes for pancreatic cancer imaging

    Science.gov (United States)

    Yong, Ken-Tye

    2009-01-01

    This work presents a novel approach to producing manganese (Mn)-doped quantum dots (Mnd-QDs) emitting in the near-infrared (NIR). Surface functionalization of Mnd-QDs with lysine makes them stably disperse in aqueous media and able to conjugate with targeting molecules. The nanoparticles were structurally and compositionally characterized and maintained a high photoluminescence quantum yield and displayed paramagnetism in water. The receptor-mediated delivery of bioconjugated Mnd-QDs into pancreatic cancer cells was demonstrated using the confocal microscopy technique. Cytotoxicity of Mnd-QDs on live cells has been evaluated. The NIR-emitting characteristic of the QDs has been exploited to acquire whole animal body imaging with high contrast signals. In addition, histological and blood analysis of mice have revealed that no long-term toxic effects arise from MnD-QDs. These studies suggest multimodal Mnd-QDs have the potentials as probes for early pancreatic cancer imaging and detection.

  18. Patterns of Weakness, Classification of Motor Neuron Disease, and Clinical Diagnosis of Sporadic Amyotrophic Lateral Sclerosis.

    Science.gov (United States)

    Statland, Jeffrey M; Barohn, Richard J; McVey, April L; Katz, Jonathan S; Dimachkie, Mazen M

    2015-11-01

    When approaching a patient with suspected motor neuron disease (MND), the pattern of weakness on examination helps distinguish MND from other diseases of peripheral nerves, the neuromuscular junction, or muscle. MND is a clinical diagnosis supported by findings on electrodiagnostic testing. MNDs exist on a spectrum, from a pure lower motor neuron to mixed upper and lower motor neuron to a pure upper motor neuron variant. Amyotrophic lateral sclerosis (ALS) is a progressive mixed upper and lower motor neuron disorder, most commonly sporadic, which is invariably fatal. This article describes a pattern approach to identifying MND and clinical features of sporadic ALS. Copyright © 2015 Elsevier Inc. All rights reserved.

  19. Kohderyhmäskenaarioita miesten jalkine- ja vaatemalliston suunnittelulle ja toteutukselle

    OpenAIRE

    Turunen, Niina

    2013-01-01

    Opinnäytetyön aiheena oli kohderyhmän määritys sekä jalkine- ja vaatemalliston suunnittelu potentiaalisen kohderyhmän näkökulmasta. Opinnäytetyössä selvitettiin kohderyhmä kahden suunnittelijan yhteistyönä suunnitellulle miesten jalkine- ja vaatemallistolle syys-talvi 2013 - 2014 -sesongille. Opinnäytetyön tavoitteena oli suunnitella ensimmäinen yhteinen kahden suunnittelijan mallisto yhteistyössä Hämeen ammattikorkeakoulun tekstiilin pääaineopiskelijan Laura Lepistön kanssa. Opinnäytetyö...

  20. Racial differences in motor neuron disease.

    Science.gov (United States)

    Gundogdu, Betul; Al-Lahham, Tawfiq; Kadlubar, Fred; Spencer, Horace; Rudnicki, Stacy A

    2014-03-01

    Our objective was to compare and contrast clinical features of black and white patients seen in the UAMS ALS/Motor Neuron Disease (MND) clinic from January 2001 to December 2010. Death certificate information was reviewed to determine race of Arkansans who died of ALS/MND between 1999 and 2006. We used a retrospective chart review of patients with ALS/MND seen at least once in our clinic and reviewed state death certificate data. Results showed that from 1999 to 2006, 466 Arkansas deaths were attributed (immediate or contributory) to ALS/MND; 17 (3.6%) were black, four (0.9%) other, and 445 (95.5%) white. During this period, the proportion of black Arkansans was 17%. From 2001 to 2010, we saw 330 patients with ALS/MND: 30 (9.1%) black, six (1.8%) other, 294 (89.1%) white. Average onset age for whites was 58.1 + 12.4 years, for blacks 52.8 + 13.0 (p = 0.038). Gender, onset site, time from symptom onset to first clinic visit and initial vital capacity were similar between the groups. Initial ALSFRS-R was 37.5 + 7.2 for whites and 30.8 + 8.5 (p = 0.004) for blacks. A first or second degree relative with ALS/MND was reported by 8.1% of whites and by none of the black patients (p = 0.15). Riluzole, PEG and non-invasive ventilation use was similar between the groups. Median tracheostomy-free survival was 36 months for white and 40 months for black patients (p = 0.475). In conclusion, although blacks appear relatively spared from ALS/MND, they present at an earlier age and are functionally worse at their first visit. Investigating the genetic make-up of blacks with the disease may help identify genes that modify risk of developing ALS/MND.

  1. Racial differences in motor neuron disease

    Science.gov (United States)

    GUNDOGDU, BETUL; AL-LAHHAM, TAWFIQ; SPENCER, HORACE; RUDNICKI, STACY A.

    2014-01-01

    Our objective was to compare and contrast clinical features of black and white patients seen in the UAMS ALS/Motor Neuron Disease (MND) clinic from January 2001 to December 2010. Death certificate information was reviewed to determine race of Arkansans who died of ALS/MND between 1999 and 2006. We used a retrospective chart review of patients with ALS/MND seen at least once in our clinic and reviewed state death certificate data. Results showed that from 1999 to 2006, 466 Arkansas deaths were attributed (immediate or contributory) to ALS/MND; 17 (3.6%) were black, four (0.9%) other, and 445 (95.5%) white. During this period, the proportion of black Arkansans was 17%. From 2001 to 2010, we saw 330 patients with ALS/MND: 30 (9.1%) black, six (1.8%) other, 294 (89.1%) white. Average onset age for whites was 58.1 ± 12.4 years, for blacks 52.8 ± 13.0 (p = 0.038). Gender, onset site, time from symptom onset to first clinic visit and initial vital capacity were similar between the groups. Initial ALSFRS-R was 37.5 ± 7.2 for whites and 30.8 ± 8.5 (p = 0.004) for blacks. A first or second degree relative with ALS/MND was reported by 8.1% of whites and by none of the black patients (p = 0.15). Riluzole, PEG and non-invasive ventilation use was similar between the groups. Median tracheostomy-free survival was 36 months for white and 40 months for black patients (p = 0.475). In conclusion, although blacks appear relatively spared from ALS/MND, they present at an earlier age and are functionally worse at their first visit. Investigating the genetic make-up of blacks with the disease may help identify genes that modify risk of developing ALS/MND. PMID:24067242

  2. A Temporal Association between Accumulated Petrol (Gasoline Lead Emissions and Motor Neuron Disease in Australia

    Directory of Open Access Journals (Sweden)

    Mark A. S. Laidlaw

    2015-12-01

    Full Text Available Background: The age standardised death rate from motor neuron disease (MND has increased from 1.29 to 2.74 per 100,000, an increase of 112.4% between 1959 and 2013. It is clear that genetics could not have played a causal role in the increased rate of MND deaths over such a short time span. We postulate that environmental factors are responsible for this rate increase. We focus on lead additives in Australian petrol as a possible contributing environmental factor. Methods: The associations between historical petrol lead emissions and MND death trends in Australia between 1962 and 2013 were examined using linear regressions. Results: Regression results indicate best fit correlations between a 20 year lag of petrol lead emissions and age-standardised female death rate (R2 = 0.86, p = 4.88 × 10−23, male age standardised death rate (R2 = 0.86, p = 9.4 × 10−23 and percent all cause death attributed to MND (R2 = 0.98, p = 2.6 × 10−44. Conclusion: Legacy petrol lead emissions are associated with increased MND death trends in Australia. Further examination of the 20 year lag between exposure to petrol lead and the onset of MND is warranted.

  3. [Removal Kinetics and Mechanism of Aniline by Manganese-oxide-modified Diatomite].

    Science.gov (United States)

    Xiao, Shao-dan; Liu, Lu; Jiang, Li-ying; Chen, Jian-meng

    2015-06-01

    A novel rapid green one-step method was developed for the preparation of manganese modified diatomite (Mn-D) by treating roasted diatomite with an acidic permanganate solution. The effects of calcination temperature and mass ratio of KMnO4 and diatomite (p) on aniline removal efficiency of Mn-D were investigated. The removal kinetics and mechanism of aniline by Mn-D were also discussed. The results showed that when the optimal calcination temperature was 450 degrees C, p was 1.6, and the loading amounts of δ-MnO2 was 0.82 g x g(-1), Mn-D had a great performance for aniline removal, and more than 80% of aniline was adsorbed within 10 minutes, accompanied with the release of Mn2+. In acidic conditions, the adsorption process on Mn-D followed pseudo-second-order and was mainly controlled by intra-particle diffusion. The best fitting of the experimental adsorption data was given by the Freundlich equation. Gas chromatograph-mass spectrometer was applied to identify the reaction intermediates at different times, and azobenzene was found to be the main reaction intermediate in the degradation system. Based on the above observations, the possible degradation pathway of aniline by Mn-D was proposed.

  4. Feasibility, acceptability, and potential effectiveness of dignity therapy for people with motor neurone disease.

    Directory of Open Access Journals (Sweden)

    Brenda Bentley

    Full Text Available BACKGROUND: Motor neurone disease (MND practice guidelines suggest developing interventions that will promote hope, meaning, and dignity to alleviate psychological distress, but very little research has been done. This study begins to address this need by exploring the use of dignity therapy with people with MND. Dignity therapy is a brief psychotherapy that promotes hope, meaning and dignity, and enhances the end of life for people with advanced cancer. The aims of this study are to assess the feasibility, acceptability, and potential effectiveness of dignity therapy for people with MND. METHODS/DESIGN: This cross-sectional feasibility study used a one-group pre-test post-test design with 29 people diagnosed with MND. Study participants completed the following self-report questionnaires: Herth Hope Index, FACIT-sp, Patient Dignity Inventory, ALS Assessment Questionnaire, ALS Cognitive Behavioural Screen, and a demographic and health history questionnaire. Acceptability was measured with a 25-item feedback questionnaire. Feasibility was assessed by examining the length of time taken to complete dignity therapy and how symptoms common in MND affected the intervention. Generalised linear mixed models and reliable change scores were used to analyse the data. RESULTS: There were no significant pre-test post-test changes for hopefulness, spirituality or dignity on the group level, but there were changes in hopefulness on the individual level. The results of the feedback questionnaire indicates dignity therapy is highly acceptable to people with MND, who report benefits similar to those in the international randomised controlled trial on dignity therapy, a population who primarily had end-stage cancer. Benefits include better family relationships, improved sense of self and greater acceptance. Dignity therapy with people with MND is feasible if the therapist can overcome time and communication difficulties. CONCLUSIONS: Dignity therapy for people with

  5. Saaremaa XX sajandil

    Index Scriptorium Estoniae

    2000-01-01

    Järg Jan/8;11;15;20;27 Feb/1;10;12;17;19;29 Mar/4;7;11;14;21;25;29;30 Apr/1;8;12;27 May/3;6;11;19;26;30 Jun/3;6;16;21;22 Jul/25 Aug/4;11;18;26 Sep/9;16;22;29 Oct/6;10;21;27 Nov/7;11;17;22 Dec/12 Sündmustest Saaremaal. Artiklite autorid: Raul Salumäe, Marko Püüa, Endel Püüa, Külli Rikas, Maret Soorsk, Olavi Pesti, Bruno Pao, Sirje Azarov, Tõnu Talvi

  6. The Effectiveness of Prophylactic Modified Neck Dissection for Reducing the Development of Lymph Node Recurrence of Papillary Thyroid Carcinoma.

    Science.gov (United States)

    Ito, Yasuhiro; Miyauchi, Akira; Kudo, Takumi; Kihara, Minoru; Fukushima, Mitsuhiro; Miya, Akihiro

    2017-09-01

    The most frequent recurrence site of papillary thyroid carcinoma (PTC) is the cervical lymph nodes. The introduction of an electric linear probe for use with ultrasonography in 1996 improved preoperative lateral neck evaluations. Before 2006, however, our hospital routinely performed prophylactic modified neck dissection (p-MND) for N0 or N1a PTCs >1 cm to prevent node recurrence. In 2006, we changed our policy and the indications for p-MND to PTCs >3 cm and/or with significant extrathyroid extension. Here, we retrospectively compared lymph node recurrence-free survival between PTCs with/without p-MND. We examined the cases of N0 or N1 and M0 PTC patients who underwent initial surgery in 1992-2012. To compare lymph node recurrence-free survival between patients who did/did not undergo p-MND, we divided these patients into three groups (excluding those whose surgery was in 2006): the 2045 patients whose surgery was performed in 1992-1996 (Group 1), the 2989 with surgery between 1997 (post-introduction of ultrasound electric linear probes) and 2005 (Group 2), and the 5332 operated on in 2007-2012 (Group 3). The p-MND performance rate of Group 3 (9%) was much lower than that of Group 1 (80%), but the lymph node recurrence-free survival of the former was significantly better, probably due to differences in clinical features and neck evaluations by ultrasound between the two groups. Our analysis of the patients aged Abolishing routine p-MND for PTCs in 2006 did not decrease lymph node recurrence-free survival, probably due to improved ultrasound preoperative neck evaluations and clinical feature changes. Selective p-MND for high-risk cases improved lymph node recurrence-free survival.

  7. The TiM system: developing a novel telehealth service to improve access to specialist care in motor neurone disease using user-centered design.

    Science.gov (United States)

    Hobson, Esther V; Baird, Wendy O; Partridge, Rebecca; Cooper, Cindy L; Mawson, Susan; Quinn, Ann; Shaw, Pamela J; Walsh, Theresa; Wolstenholme, Daniel; Mcdermott, Christopher J

    2018-08-01

    Attendance at a specialist multidisciplinary motor neurone disease (MND) clinic is associated with improved survival and may also improve quality of life and reduce hospital admissions. However, patients struggle to travel to clinic and may experience difficulties between clinic visits that may not be addressed in a timely manner. We wanted to explore how we could improve access to specialist MND care. We adopted an iterative, user-centered co-design approach, collaborating with those with experience of providing and receiving MND care including patients, carers, clinicians, and technology developers. We explored the unmet needs of those living with MND, how they might be met through service redesign and through the use of digital technologies. We developed a new digital solution and performed initial testing with potential users including clinicians, patients, and carers. We used these findings to develop a telehealth system (TiM) using an Android app into which patients and carers answer a series of questions about their condition on a weekly basis. The questions aim to capture all the physical, emotional, and social difficulties associated with MND. This information is immediately uploaded to the internet for review by the MND team. The data undergoes analysis in order to alert clinicians to any changes in a patient or carer's condition. We describe the benefits of developing a novel digitally enabled service underpinned by participatory design. Future trials must evaluate the feasibility and acceptability of the TiM system within a clinical environment.

  8. Myonuclear domain size and myosin isoform expression in muscle fibres from mammals representing a 100,000-fold difference in body size.

    Science.gov (United States)

    Liu, Jing-Xia; Höglund, Anna-Stina; Karlsson, Patrick; Lindblad, Joakim; Qaisar, Rizwan; Aare, Sudhakar; Bengtsson, Ewert; Larsson, Lars

    2009-01-01

    This comparative study of myonuclear domain (MND) size in mammalian species representing a 100,000-fold difference in body mass, ranging from 25 g to 2500 kg, was undertaken to improve our understanding of myonuclear organization in skeletal muscle fibres. Myonuclear domain size was calculated from three-dimensional reconstructions in a total of 235 single muscle fibre segments at a fixed sarcomere length. Irrespective of species, the largest MND size was observed in muscle fibres expressing fast myosin heavy chain (MyHC) isoforms, but in the two smallest mammalian species studied (mouse and rat), MND size was not larger in the fast-twitch fibres expressing the IIA MyHC isofom than in the slow-twitch type I fibres. In the larger mammals, the type I fibres always had the smallest average MND size, but contrary to mouse and rat muscles, type IIA fibres had lower mitochondrial enzyme activities than type I fibres. Myonuclear domain size was highly dependent on body mass in the two muscle fibre types expressed in all species, i.e. types I and IIA. Myonuclear domain size increased in muscle fibres expressing both the beta/slow (type I; r = 0.84, P fast IIA MyHC isoform (r = 0.90; P muscle fibre type, independent of species. However, myosin isoform expression is not the sole protein determining MND size, and other protein systems, such as mitochondrial proteins, may be equally or more important determinants of MND size.

  9. Exploring the Role of PGC-1α in Defining Nuclear Organisation in Skeletal Muscle Fibres.

    Science.gov (United States)

    Ross, Jacob A; Pearson, Adam; Levy, Yotam; Cardel, Bettina; Handschin, Christoph; Ochala, Julien

    2017-06-01

    Muscle fibres are multinucleated cells, with each nucleus controlling the protein synthesis in a finite volume of cytoplasm termed the myonuclear domain (MND). What determines MND size remains unclear. In the present study, we aimed to test the hypothesis that the level of expression of the transcriptional coactivator PGC-1α and subsequent activation of the mitochondrial biogenesis are major contributors. Hence, we used two transgenic mouse models with varying expression of PGC-1α in skeletal muscles. We isolated myofibres from the fast twitch extensor digitorum longus (EDL) and slow twitch diaphragm muscles. We then membrane-permeabilised them and analysed the 3D spatial arrangements of myonuclei. In EDL muscles, when PGC-1α is over-expressed, MND volume decreases; whereas, when PGC-1α is lacking, no change occurs. In the diaphragm, no clear difference was noted. This indicates that PGC-1α and the related mitochondrial biogenesis programme are determinants of MND size. PGC-1α may facilitate the addition of new myonuclei in order to reach MND volumes that can support an increased mitochondrial density. J. Cell. Physiol. 232: 1270-1274, 2017. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  10. Sorption of Cr(III) ion from aqueous solution by two kinds of modified diatomite.

    Science.gov (United States)

    Li, Er; Zeng, Xiangying

    2012-01-01

    Raw diatomite modified by microemulsion (DMM) and manganese oxide (MnD) were used for the removal of Cr(III) ions from aqueous solution. The characteristics and performance of these two types of modified diatomite on Cr(III) ion adsorption were compared. The results indicate that the Cr(III) ion adsorption capacities of diatomite were considerably improved after modifications by manganese oxide (MnO) and microemulsion. The surface area of MnD was increased because of the formation of MnO on the diatomite surface, and that of DMM was promoted owing to the existence of the hydrolyzed aromatic acid. Because of the stronger surface ionized function, the adsorption performance of Cr(III) ions in DMM was better than that in MnD. Within the experimental range of pH (i.e. 2.2-6.3), the Cr(III) ion removal of DMM (35-70%) was higher than that of MnD (33-59%) owing to the different electrostatic forces between the Cr(III) ion and the surface of the modified diatomite. The Cr(III) ion removal in MnD and DMM was improved with the increase of synthetic solution concentration in volumes from 0 to 2,500 mL.

  11. TDP-43 pathology in familial frontotemporal dementia and motor neuron disease without Progranulin mutations.

    NARCIS (Netherlands)

    Seelaar, H.; Schelhaas, H.J.; Azmani, A.; Kusters, B.; Rosso, S.; Majoor-Krakauer, D.F.; Rijik, M.C. de; Rizzu, P.; Brummelhuis, M. Ten; Doorn, P.A. van; Kamphorst, W.; Willemsen, R.; Swieten, J. van

    2007-01-01

    Frontotemporal dementia is accompanied by motor neuron disease (FTD + MND) in approximately 10% of cases. There is accumulating evidence for a clinicopathological overlap between FTD and MND based on observations of familial aggregation and neuropathological findings of ubiquitin-positive neuronal

  12. TDP-43 pathology in familial frontotemporal dementia and motor neuron disease without Progranulin mutations

    NARCIS (Netherlands)

    H. Seelaar (Harro); H. Jurgen Schelhaas; A. Azmani (Asma); B. Küsters (Benno); S.M. Rosso (Sonia); D.F. Majoor-Krakauer (Danielle); M.C. de Rijik (Maarten); P. Rizzu (Patrizia); M. ten Brummelhuis (Ming); P.A. van Doorn (Pieter); W. Kamphorst (Wouter); R. Willemsen (Rob); J.C. van Swieten (John)

    2007-01-01

    textabstractFrontotemporal dementia is accompanied by motor neuron disease (FTD + MND) in ∼10% of cases. There is accumulating evidence for a clinicopathological overlap between FTD and MND based on observations of familial aggregation and neuropathological findings of ubiquitin-positive neuronal

  13. Is dignity therapy feasible to enhance the end of life experience for people with motor neurone disease and their family carers?

    Directory of Open Access Journals (Sweden)

    Bentley Brenda

    2012-09-01

    Full Text Available Abstract Background Development of interventions that address psychosocial and existential distress in people with motor neurone disease (MND or that alleviate caregiver burden in MND family carers have often been suggested in the research literature. Dignity therapy, which was developed to reduce psychosocial and existential distress at the end of life, has been shown to benefit people dying of cancer and their families. These results may not be transferable to people with MND. The objectives of this study are to assess the feasibility, acceptability and potential effectiveness of dignity therapy to enhance the end of life experience for people with motor neurone disease and their family carers. Methods/design This is a cross-sectional study utilizing a single treatment group and a pre/post test design. The study population will comprise fifty people diagnosed with MND and their nominated family carers. Primarily quantitative outcomes will be gathered through measures assessed at baseline and at approximately one week after the intervention. Outcomes for participants include hopefulness, spirituality and dignity. Outcomes for family carers include perceived caregiver burden, hopefulness and anxiety/depression. Feedback and satisfaction with the intervention will be gathered through a questionnaire. Discussion This detailed research will explore if dignity therapy has the potential to enhance the end of life experience for people with MND and their family carers, and fill a gap for professionals who are called on to address the spiritual, existential and psychosocial needs of their MND patients and families. Trial registration ACTRN Trial Number: ACTRN12611000410954

  14. Comparison of Performance of the VIP and WMT in a Criminal Forensic Sample.

    Science.gov (United States)

    Fazio, Rachel L; Denney, Robert L

    2018-01-24

    To compare the efficacy of the Validity Indicator Profile (VIP) and Word Memory Test (WMT) in a criminal forensic population. Potential participants included 225 male evaluees from a maximum-security Federal prison referred for neuropsychological evaluation for either forensic purposes or for suspected neurocognitive dysfunction as part of a medical evaluation. Examinees were included in the analysis if administered the VIP (Verbal, Nonverbal, or both tests) and WMT along with at least two other freestanding PVTs; 74 satisfied these criteria. Participants were then categorized as having probable Malingered Neurocognitive Dysfunction (+MND) if they failed at least two freestanding validity indicators, negative for MND (-MND) if they passed all indicators, and Possible MND (pMND) if they failed one indicator. Groups were very demographically similar. There were significant differences in WMT scores and distribution of VIP profiles across groups. Whether using traditional or investigative cut scores, and whether using the WMT with or without consideration of a GMIP profile, the WMT demonstrated superior sensitivity and specificity on nearly every comparison. The VIP, when interpreted in the traditional fashion, and the WMT with GMIP, both had more than adequate psychometric properties when used with criminal forensic evaluees, strengthening the body of literature supporting their use for these types of evaluations. Counting a positive on either of the VIP subtests as an indication of +MND improves the psychometric properties of the VIP slightly, although the WMT had the better overall classification accuracy. © The Author(s) 2018. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  15. Decision-making and referral processes for patients with motor neurone disease: a qualitative study of GP experiences and evaluation of a new decision-support tool.

    Science.gov (United States)

    Baxter, Susan; McDermott, Christopher J

    2017-05-08

    The diagnosis of motor neurone disease (MND) is known to be challenging and there may be delay in patients receiving a correct diagnosis. This study investigated the referral process for patients who had been diagnosed with MND, and whether a newly-developed tool (The Red Flags checklist) might help General Practitioners (GPs) in making referral decisions. We carried out interviews with GPs who had recently referred a patient diagnosed with MND, and interviews/surveys with GPs who had not recently referred a patient with suspected MND. We collected data before the Red Flags checklist was introduced; and again one year later. We analysed the data to identify key recurring themes. Forty two GPs took part in the study. The presence of fasciculation was the clinical feature that most commonly led to consideration of a potential MND diagnosis. GPs perceived that their role was to make onward referrals rather than attempting to make a diagnosis, and delays in correct diagnosis tended to occur at the specialist level. A quarter of participants had some awareness of the newly-developed tool; most considered it useful, if incorporated into existing systems. While fasciculation is the most common symptom associated with MND, other bulbar, limb or respiratory features, together with progression should be considered. There is a need for further research into how decision-support tools should be designed and provided, in order to best assist GPs with referral decisions. There is also a need for further work at the level of secondary care, in order that referrals made are re-directed appropriately.

  16. Record linkage between hospital discharges and mortality registries for motor neuron disease case ascertainment for the Spanish National Rare Diseases Registry.

    Science.gov (United States)

    Ruiz, Elena; Ramalle-Gómara, Enrique; Quiñones, Carmen

    2014-06-01

    Our objective was to analyse the coverage of hospital discharge data and the mortality registry (MR) of La Rioja to ascertain motor neuron disease (MND) cases to be included in the Spanish National Rare Diseases Registry. MND cases that occurred in La Rioja during the period 1996-2011 were selected from hospital discharge data and the MR by means of the International Classification of Diseases. Review of the medical histories was carried out to confirm the causes of death reported. Characteristics of the population with MND were analysed. A total of 133 patients with MND were detected in La Rioja during the period 1996-2011; 30.1% were only recorded in the hospital discharges data, 12.0% only in the MR, and 57.9% were recorded by both databases. Medical records revealed a miscoding of patients who had been diagnosed with progressive supranuclear palsy but were recorded in the MR with an MND code. In conclusion, the hospital discharges data and the MR appear to be complementary and are valuable databases for the Spanish National Rare Diseases Registry when MNDs are properly codified. Nevertheless, it would be advisable to corroborate the validity of the MR as data source since the miscoding of progressive supranuclear palsy has been corrected.

  17. Being Yourself and Thinking About the Future in People With Motor Neuron Disease: A Grounded Theory of Self-care Processes.

    Science.gov (United States)

    Bassola, Barbara; Sansone, Valeria Ada; Lusignani, Maura

    2018-06-01

    Self-care is a crucial aspect in the management of people with motor neuron disease (MND). Nurses and healthcare professionals must know the processes used by patients in performing self-care to identify problems and help them. Decision-making processes, self-understanding, and political and social support influence the self-care process in chronic diseases. Little is known about the self-care process in MND. The aim of this study was to gain insight on the self-care processes in people with MND. A grounded theory method was chosen for this study. Data from interviews were gathered, and a simultaneous comparative analysis was conducted to identify categories and codes. Twenty-one people with spinal muscular atrophy and amyotrophic lateral sclerosis participated in the study. Five categories were identified as grounded in the data. The process starts from "being yourself in the care," and it develops thanks to "growing and changing" and with a "thinking about the future" approach. "Family role" and "you and who helps you" categories affect the process itself. The self-care process in people with MND is not seen in a daily perspective but changes with the evolution of the disease. For the growing patients with MND, changing, accepting and controlling the disease while deciding autonomously are the foundations of the process.

  18. Interactions of Aging, Overload, and Creatine Supplementation in Rat Plantaris Muscle

    Directory of Open Access Journals (Sweden)

    Mark D. Schuenke

    2011-01-01

    Full Text Available Attenuation of age-related sarcopenia by creatine supplementation has been equivocal. In this study, plantaris muscles of young (Y; 5m and aging (A; 24m Fisher 344 rats underwent four weeks of either control (C, creatine supplementation (Cr, surgical overload (O, or overload plus creatine (OCr. Creatine alone had no effect on muscle fiber cross-sectional area (CSA or heat shock protein (HSP70 and increased myonuclear domain (MND only in young rats. Overload increased CSA and HSP70 content in I and IIA fibers, regardless of age, and MND in IIA fibers of YO rats. CSA and MND increased in all fast fibers of YOCr, and CSA increased in I and IIA fibers of AOCr. OCR did not alter HSP70, regardless of age. MND did not change in aging rats, regardless of treatment. These data indicate creatine alone had no significant effect. Creatine with overload produced no additional hypertrophy relative to overload alone and attenuated overload-induced HSP70 expression.

  19. Structural and functional brain signatures of C9orf72 in motor neuron disease.

    Science.gov (United States)

    Agosta, Federica; Ferraro, Pilar M; Riva, Nilo; Spinelli, Edoardo Gioele; Domi, Teuta; Carrera, Paola; Copetti, Massimiliano; Falzone, Yuri; Ferrari, Maurizio; Lunetta, Christian; Comi, Giancarlo; Falini, Andrea; Quattrini, Angelo; Filippi, Massimo

    2017-09-01

    This study investigated structural and functional magnetic resonance imaging abnormalities in hexanucleotide repeat expansion in chromosome 9 open reading frame 72 (C9orf72) motor neuron disease (MND) relative to disease severity-matched sporadic MND cases. We enrolled 19 C9orf72 and 67 disease severity-matched sporadic MND patients, and 22 controls. Sporadic cases were grouped in patients with: no cognitive/behavioral deficits (sporadic-motor); same patterns of cognitive/behavioral impairment as C9orf72 cases (sporadic-cognitive); shorter disease duration versus other sporadic groups (sporadic-early). C9orf72 patients showed cerebellar and thalamic atrophy versus all sporadic cases. All MND patients showed motor, frontal, and temporoparietal cortical thinning and motor and extramotor white matter damage versus controls, independent of genotype and presence of cognitive impairment. Compared with sporadic-early, C9orf72 patients revealed an occipital cortical thinning. C9orf72 patients had enhanced visual network functional connectivity versus sporadic-motor and sporadic-early cases. Structural cerebellar and thalamic damage and posterior cortical alterations are the brain magnetic resonance imaging signatures of C9orf72 MND. Frontotemporal cortical and widespread white matter involvement are likely to be an effect of the disease evolution rather than a C9orf72 marker. Copyright © 2017 Elsevier Inc. All rights reserved.

  20. The MY NASA DATA Project: Preparing Future Earth and Environmental Scientists, and Future Citizens

    Science.gov (United States)

    Chambers, L. H.; Phelps, C. S.; Phipps, M.; Holzer, M.; Daugherty, P.; Poling, E.; Vanderlaan, S.; Oots, P. C.; Moore, S. W.; Diones, D. D.

    2008-12-01

    For the past 5 years, the MY NASA DATA (MND) project at NASA Langley has developed and adapted tools and materials aimed at enabling student access to real NASA Earth science satellite data. These include web visualization tools including Google Earth capabilities, but also GPS and graphing calculator exercises, Excel spreadsheet analyses, and more. The project team, NASA scientists, and over 80 classroom science teachers from around the country, have created over 85 lesson plans and science fair project ideas that demonstrate NASA satellite data use in the classroom. With over 150 Earth science parameters to choose from, the MND Live Access Server enables scientific inquiry on numerous interconnected Earth and environmental science topics about the Earth system. Teachers involved in the project report a number of benefits, including networking with other teachers nationwide who emphasize data collection and analysis in the classroom, as well as learning about other NASA resources and programs for educators. They also indicate that the MND website enhances the inquiry process and facilitates the formation of testable questions by students (a task that is typically difficult for students to do). MND makes science come alive for students because it allows them to develop their own questions using the same data scientists use. MND also provides educators with a rich venue for science practice skills, which are often overlooked in traditional curricula as teachers concentrate on state and national standards. A teacher in a disadvantaged school reports that her students are not exposed to many educational experiences outside the classroom. MND allows inner city students to be a part of NASA directly. They are able to use the same information that scientists are using and this gives them inspiration. In all classrooms, the MND microsets move students out of their local area to explore global data and then zoom back into their homes realizing that they are a part of the

  1. Spatially complex distribution of dissolved manganese in a fjord as revealed by high-resolution in situ sensing using the autonomous underwater vehicle Autosub.

    Science.gov (United States)

    Statham, P J; Connelly, D P; German, C R; Brand, T; Overnell, J O; Bulukin, E; Millard, N; McPhail, S; Pebody, M; Perrett, J; Squire, M; Stevenson, P; Webb, A

    2005-12-15

    Loch Etive is a fjordic system on the west coast of Scotland. The deep waters of the upper basin are periodically isolated, and during these periods oxygen is lost through benthic respiration and concentrations of dissolved manganese increase. In April 2000 the autonomous underwater vehicle (AUV) Autosub was fitted with an in situ dissolved manganese analyzer and was used to study the spatial variability of this element together with oxygen, salinity, and temperature throughout the basin. Six along-loch transects were completed at either constant height above the seafloor or at constant depth below the surface. The ca. 4000 in situ 10-s-average dissolved Mn (Mnd) data points obtained provide a new quasi-synoptic and highly detailed view of the distribution of manganese in this fjordic environment not possible using conventional (water bottle) sampling. There is substantial variability in concentrations (600 nM) and distributions of Mnd. Surface waters are characteristically low in Mnd reflecting mixing of riverine and marine end-member waters, both of which are low in Mnd. The deeper waters are enriched in Mnd, and as the water column always contains some oxygen, this must reflect primarily benthic inputs of reduced dissolved Mn. However, this enrichment of Mnd is spatially very variable, presumably as a result of variability in release of Mn coupled with mixing of water in the loch and removal processes. This work demonstrates how AUVs coupled with chemical sensors can reveal substantial small-scale variability of distributions of chemical species in coastal environments that would not be resolved by conventional sampling approaches. Such information is essential if we are to improve our understanding of the nature and significance of the underlying processes leading to this variability.

  2. Progressive Apraxia of Speech as a Sign of Motor Neuron Disease

    Science.gov (United States)

    Duffy, Joseph R.; Peach, Richard K.; Strand, Edythe A.

    2007-01-01

    Purpose: To document and describe in detail the occurrence of apraxia of speech (AOS) in a group of individuals with a diagnosis of motor neuron disease (MND). Method: Seven individuals with MND and AOS were identified from among 80 patients with a variety of neurodegenerative diseases and AOS (J. R. Duffy, 2006). The history, presenting…

  3. NEUROBEHAVIORAL RELATIONSHIPS AND PUBERTY - ANOTHER TRANSFORMATION

    NARCIS (Netherlands)

    SOORANILUNSING, RJ

    In a follow-up study of the Groningen Perinatal Project (GPP) on minor neurological dysfunction (MND) at 12 and 14 years the onset of puberty appeared to play a role. The children were selected on the presence (n = 185) and absence (n = 185) of MND at 9 years. Puberty was defined by the presence of

  4. Selective impairment of verb processing associated with pathological changes in Brodmann areas 44 and 45 in the motor neurone disease-dementia-aphasia syndrome.

    Science.gov (United States)

    Bak, T H; O'Donovan, D G; Xuereb, J H; Boniface, S; Hodges, J R

    2001-01-01

    We report six patients with clinically diagnosed and electrophysiologically confirmed motor neurone disease (MND), in whom communication problems were an early and dominant feature. All patients developed a progressive non-fluent aphasia culminating in some cases in complete mutism. In five cases, formal testing revealed deficits in syntactic comprehension. Comprehension and production of verbs were consistently more affected those that of nouns and this effect remained stable upon subsequent testing, despite overall deterioration. The classical signs of MND, including wasting, fasciculations and severe bulbar symptoms, occurred over the following 6-12 months. The behavioural symptoms ranged from mild anosognosia to personality change implicating frontal-lobe dementia. In three cases, post-mortem examination has confirmed the clinical diagnosis of MND-dementia. In addition to the typical involvement of motor and premotor cortex, particularly pronounced pathological changes were observed in the Brodmann areas 44 (Broca's area) and 45. The finding of a selective impairment of verb/action processing in association with the dementia/aphasia syndrome of MND suggests that the neural substrate underlying verb representation is strongly connected to anterior cortical motor systems.

  5. Symptomatic treatments for amyotrophic lateral sclerosis/motor neuron disease.

    Science.gov (United States)

    Ng, Louisa; Khan, Fary; Young, Carolyn A; Galea, Mary

    2017-01-10

    Motor neuron disease (MND), which is also known as amyotrophic lateral sclerosis (ALS), causes a wide range of symptoms but the evidence base for the effectiveness of the symptomatic treatment therapies is limited. To summarise the evidence from Cochrane Systematic Reviews of all symptomatic treatments for MND. We searched the Cochrane Database of Systematic Reviews (CDSR) on 15 November 2016 for systematic reviews of symptomatic treatments for MND. We assessed the methodological quality of the included reviews using the Assessment of Multiple Systematic Reviews (AMSTAR) tool and the GRADE approach. We followed standard Cochrane study (review) selection and data extraction procedures. We reported findings narratively and in tables. We included nine Cochrane Systematic Reviews of interventions to treat symptoms in people with MND. Three were empty reviews with no included randomised controlled trials (RCTs); however, all three reported on non-RCT evidence and the remaining six included mostly one or two studies. We deemed all of the included reviews of high methodological quality. Drug therapy for painThere is no RCT evidence in a Cochrane Systematic Review exploring the efficacy of drug therapy for pain in MND. Treatment for crampsThere is evidence (13 RCTs, N = 4012) that for the treatment of cramps in MND, compared to placebo:- memantine and tetrahydrocannabinol (THC) are probably ineffective (moderate-quality evidence);- vitamin E may have little or no effect (low-quality evidence); and- the effects of L-threonine, gabapentin, xaliproden, riluzole, and baclofen are uncertain as the evidence is either very low quality or the trial specified the outcome but did not report numerical data.The review reported adverse effects of riluzole, but it is not clear whether other interventions had adverse effects. Treatment for spasticityIt is uncertain whether an endurance-based exercise programme improved spasticity or quality of life, measured at three months after the

  6. Incidence of and risk factors for Motor Neurone Disease in UK women: a prospective study

    Directory of Open Access Journals (Sweden)

    Doyle Pat

    2012-05-01

    Full Text Available Abstract Background Motor neuron disease (MND is a severe neurodegenerative disease with largely unknown etiology. Most epidemiological studies are hampered by small sample sizes and/or the retrospective collection of information on behavioural and lifestyle factors. Methods 1.3 million women from the UK Million Women Study, aged 56 years on average at recruitment, were followed up for incident and/or fatal MND using NHS hospital admission and mortality data. Adjusted relative risks were calculated using Cox regression models. Findings During follow-up for an average of 9·2 years, 752 women had a new diagnosis of MND. Age-specific rates increased with age, from 1·9 (95% CI 1·3 – 2·7 to 12·5 (95% CI 10·2 – 15·3 per 100,000 women aged 50–54 to 70–74, respectively, giving a cumulative risk of diagnosis with the disease of 1·74 per 1000 women between the ages of 50 and 75 years. There was no significant variation in risk of MND with region of residence, socio-economic status, education, height, alcohol use, parity, use of oral contraceptives or hormone replacement therapy. Ever-smokers had about a 20% greater risk than never smokers (RR 1·19 95% CI 1·02 to 1·38, p = 0·03. There was a statistically significant reduction in risk of MND with increasing body mass index (pfor trend = 0·009: obese women (body mass index, 30 kg/m2 or more had a 20% lower risk than women of normal body mass index (20 to 2(RR 0·78 95% CI 0·65-0·94; p = 0·03. This effect persisted after exclusion of the first three years of follow-up. Interpretation MND incidence in UK women rises rapidly with age, and an estimated 1 in 575 women are likely to be affected between the ages of 50 and 75 years. Smoking slightly increases the risk of MND, and adiposity in middle age is associated with a lower risk of the disease.

  7. Juhatuse aruanne : esitatud aastakoosolekul 28. veebruaril 2002 / Krista Talvi

    Index Scriptorium Estoniae

    Talvi, Krista, 1948-

    2002-01-01

    Ka EARist: juhatuse aseesinaine K. Kaugver, liige S. Lauring Vaska; mainitud A. Normak, A. Limberg, K. Bobrov, T. Reimo, M. Aasmets; liigitamise ja märksõnastamise toimkonna (eesotsas A.-M. Kirsel) ja raamatuvarade kaitse töörühma (eesotsas A. Veinberg) tööst; EARis ja EARi töötajate kaasabil toimunud üritustest

  8. Eesti Raamatukoguhoidjate Ühingu tegevusest 2002. aastal / Krista Talvi

    Index Scriptorium Estoniae

    Talvi, Krista, 1948-

    2003-01-01

    Ka EARis 2002. a. toimunust; mainitud ka EARi töötajaid : lk. 155, 157, 167 K. Kaugver; lk. 155 J. Kaps; lk. 160, 165 T. Reimo, lk. 164 A.-M. Kirsel; lk. 164, 167 M. Aasmets; lk. 165 A. Valmas; lk. 165 A. Kruus

  9. Kultuuripärandita pole pärandit / Krista Talvi

    Index Scriptorium Estoniae

    Talvi, Krista, 1948-

    2013-01-01

    30. juulist kuni 1. augustini 2013 toimus Kultuuriministeeriumi, Rahvusraamatukogu ja Sillamäe Keskraamatukogu ühisettevõtmisena rahvaraamatukogude suvelaager "Raamatukogu on kutuuripärandi kandja"

  10. Kus me kange bestseller? / Peeter Künstler

    Index Scriptorium Estoniae

    Künstler, Peeter, 1958-2009

    2000-01-01

    Arvustus: Uustulnd, Lembit. Kiikhobune Antverpenist. Tallinn : Varrak, 1999 ; Tiidenberg, Ants. Vietnam-transiit Tallinn : SE & JS, 1999 ; Tamman, Tiina. Tihe udu Tallinnas. Tallinn : Perioodika, 2000

  11. Tiina Tammetalu vahemerelised akvarellid / tekst ja akvarellid Tiina Tammetalu

    Index Scriptorium Estoniae

    Tammetalu, Tiina, 1961-

    2012-01-01

    Akvarellid "Sain Jean Cap Ferrat", "Viinamarjaväli. Minu kodus, tugitooli kohal", "Paradiisiaed. Villa et Jardins Eprussi de Rothscild", "Belle Air. 700 meetri kõrgusel õhus", "Kaatriga Saint Tropez`i", "Õnnistatud maa. Caesarea, Akko, Haifa" autori kommentaaridega

  12. Experiences and reflections of patients with motor neuron disease on breaking the news in a two-tiered appointment: a qualitative study.

    Science.gov (United States)

    Seeber, Antje A; Pols, A Jeannette; Hijdra, Albert; Grupstra, Hepke F; Willems, Dick L; de Visser, Marianne

    2016-02-02

    Breaking bad news should be fine-tuned to the individual patient, contain intelligible information, include emotional support and offer a tailor-made treatment plan. To achieve this goal in motor neuron disease (MND), neurologists of the amyotrophic lateral sclerosis (ALS) centre Amsterdam deliver the message on 2 separate visits within 14 days. To evaluate how patients with MND react to and view disclosure of the diagnosis, in this 2-tiered approach. Non-participating observations and in-depth interviews with patients were conducted in 1 tertiary ALS referral centre. Qualitative analysis consisted of inductive analysis of observation reports and verbatim typed out interviews. 10 2-tiered appointments were observed and 21 Dutch patients with MND interviewed. They experienced the straightforward message to be suffering from a fatal disease as devastating, yet unavoidable. The prospect of a short-term second appointment offered structure for the period immediately following the diagnosis. The time between appointments provided the opportunity for a first reorientation on their changed perspective on their life. The second appointment allowed for detailed discussions about various aspects of MND and a tailor-made treatment plan. The 2-tiered approach fits well with the way in which Dutch patients with MND process the disclosure of their diagnosis, gather information and handle the changed perspective on their life. It may serve as a model for other life-limiting diseases. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  13. Frontotemporal lobar degeneration with ubiquitin pathology: an autopsy case presenting with semantic dementia and upper motor neuron signs with a clinical course of 19 years.

    Science.gov (United States)

    Yokota, Osamu; Tsuchiya, Kuniaki; Itoh, Yoshinori; Ishizu, Hideki; Akiyama, Haruhiko; Ikeda, Manabu; Kuzuhara, Shigeki; Otomo, Eiichi

    2006-12-01

    We report a case of a right-handed 74-year-old man who showed semantic dementia with a disease duration of 19 years. He initially presented with excessive use of pronouns and semantic paraphasia at the age of 55 years. Impairment of object recognition developed 5 years after the onset. Face recognition impairment and stereotypic behaviors developed 11 years after onset, and pyramidal signs 2 years before death. Pathological examination disclosed circumscribed severe atrophy in not only the bilateral temporal tips but also in the left precentral gyrus and pars opercularis in a motor speech field. Pyramidal tract involvement and loss of Betz cells were also evident. On the other hand, neurons in the anterior horns and hypoglossal nuclei were spared in number, although astrocytes were mildly proliferated. Ubiquitin-positive lesions were observed in the hippocampus, and frontal and temporal cortices. Neither Bunina bodies nor Pick bodies were present. These features clinically fit the international diagnostic criteria of semantic dementia and, histopathologically, frontotemporal lobar degeneration with motor neuron disease (FTLD-MND). This case suggests that (1) the distribution of cortical lesions associated with language disturbance is not uniform in FTLD-MND. It may be that only some cases of FTLD with ubiquitin pathology develop semantic dementia despite the high incidence of language disturbance, and (2) the precentral gyrus can be severely affected in FTLD-MND. After reviewing previous cases of FTLD-MND with a clinical course of more than 10 years, we also noticed that (3) FTLD-MND cases with a long disease duration often show upper motor neuron-predominant involvement.

  14. Determinants of accepting non-invasive ventilation treatment in motor neurone disease: a quantitative analysis at point of need.

    Science.gov (United States)

    Cousins, Rosanna; Ando, Hikari; Thornton, Everard; Chakrabarti, Biswajit; Angus, Robert; Young, Carolyn

    2013-01-01

    Objectives : Motor neurone disease (MND) progressively damages the nervous system causing wasting to muscles, including those used for breathing. There is robust evidence that non-invasive ventilation (NIV) relieves respiratory symptoms and improves quality of life in MND. Nevertheless, about a third of those who would benefit from NIV decline the treatment. The purpose of the study was to understand this phenomenon. Design : A cross-sectional quantitative analysis. Methods : Data including age, sex, MND symptomatology, general physical and mental health and psychological measures were collected from 27 patients and their family caregivers at the point of being offered ventilatory support based on physiological markers. Results : Quantitative analyses indicated no difference in patient characteristics or symptomatology between those who tolerated ( n  = 17) and those who declined ( n  = 10) NIV treatment. A comparison of family caregivers found no differences in physical or mental health or in caregiving distress, emphasising that this was high in both groups; however, family caregivers supporting NIV treatment were significantly more resilient, less neurotic and less anxious than family caregivers who did not. Regression analyses, forcing MND symptoms to enter the equation first, found caregiver resilience:commitment the strongest predictor of uptake of NIV treatment adding 22% to the 56% explained variance. Conclusion : Patients who tolerated NIV treatment had family caregivers who cope through finding meaning and purpose in their situation. Psychological support and proactive involvement for family caregivers in the management of the illness situation is indicated if acceptance of NIV treatment is to be maximised in MND.

  15. Kirjastusuudiseid

    Index Scriptorium Estoniae

    2007-01-01

    Uutest kunstiraamatutest "Meistriteoste lummus. Koopia 19. sajandil" (koostaja Tiina-Mall Kreem), "Priit Pärn" (koostaja Eha Komissarov), "Henn Roode. Modernist saatuse kiuste" (koostaja Kädi Talvoja)

  16. Ülemaaline ilulugejate 15. võistulausumine

    Index Scriptorium Estoniae

    2008-01-01

    Vabariiklikust etlejate konkursist. 4.-6. klasside arvestuses võitis Grand Prix'i Markkus Pulk, laureaatideks tulid Maria Pihlak, Kenneth Norden ja Laura Elisabeth Konsand. Eripreemiad said Laura Oolup, Maria Zaitseva, žürii aitähi said Sander Aavik ja Liisa Lutter. 7.-9. klasside arvestuses võitis Grand Prix' Anna Talvi, laureaatideks tulid Liisa Saaremäel, Karmen Kozma, Riko Osila. Eripreemiad said Indrek Jõe, Eliise Seedre, žürii aitähi sai Kirke Algma. 10.-12. klasside arvestuses võitis Grand Prix' Doris Tääker, laureaatideks tulid Jörgen Liik, Virgo Ernits ja Ilja Massalov. eripreemiad said Marian Heinat ja Kadri Toomsalu. Kuressaare Gümnaasiumi õpilasžürii preemiad läksid Kenneth Nordenile, Riko Osilale ja Doris Tääkerile

  17. Jaapani animafilmid vallutavad kinod / Signe Sillasoo

    Index Scriptorium Estoniae

    Sillasoo, Signe

    2009-01-01

    Kolmas Jaapani animafilmifestival (JAFF) toimub 3.-12. aprillini Tallinna kinos Sõprus ja 6.-15. aprillini Tartus Athena keskuses. Tutvustab pressiesindaja Tiina Savi, lisatud kinos Sõprus linastuvate filmide programm

  18. Euroopa temaatika intrigeerib ja harib / Imbi Leevand

    Index Scriptorium Estoniae

    Leevand, Imbi

    2008-01-01

    ERÜ kooliraamatukogude sektsiooni teabepäevast "Kooliraamatukogu - aken Euroopasse", kus esinesid ettekandega ka TLÜ algõpetuse õppetooli lastekirjanduse dotsent Mare Müürsepp ja Tiina Sulg Tartu Linnaraamatukogust

  19. Milliseid mõtteid tekitas konverents "Tsensuur meedias ja kunstis"? / Jonas Valatkevicius, Jevgeni Tsymbal, Mark Soosaar...[jt.] ; interv. Grete Naaber

    Index Scriptorium Estoniae

    2000-01-01

    Küsimusele vastavad Vilniuse kunstikeskuse kuraator Jonas Valatkevicius, Moskva filmirežissöör Jevgeni Tsymbal, Mark Soosaar, Albaania kunstigalerii juhataja Gezim Qendro, BBC ajakirjanik Tiina Tamman

  20. Kui kaugel on Peruu? / Ricardo Mateo Durand

    Index Scriptorium Estoniae

    Durand, Ricardo Mateo

    2002-01-01

    Peruu Vabariigi aukonsul Eestis Ricardo Mateo Durand Eesti-Portugali diplomaatilistest suhetest, Eesti viisa hankimise raskustest Peruus, Lõuna-Ameerikast. Vt. samas Tiina Maiberg "Välisministeerium loodab saata Peruusse aukonsuli"

  1. "Ametniku soovitussõnastik" / Tuuli Rehemaa

    Index Scriptorium Estoniae

    Rehemaa, Tuuli, 1974-

    2014-01-01

    Tutvustus: Ametniku soovitussõnastik [Võrguteavik] / Eesti Keele Instituut ; koostanud ja toimetanud Tiina Paet, Tuuli Rehemaa, Argo Mund. Tallinn : Eesti Keele Sihtasutus, 2014. - http://www.eki.ee/dict/ametnik/

  2. Nutritional advice and treatment by dietitians to patients with amyotrophic lateral sclerosis/motor neurone disease: a survey of current practice in England, Wales, Northern Ireland and Canada.

    Science.gov (United States)

    Rio, A; Cawadias, E

    2007-02-01

    The management of amyotrophic lateral sclerosis/motor neurone disease (ALS/MND) has shifted from an attitude of nihilism to treatments that prolong survival and offer hope. Nutrition is an integral component of ALS/MND care requiring coordination among acute and community multi-disciplinary teams (MDT). Evidence-based nutrition guidelines exist for this patient group but their use among dietitians is unknown. The aim of this study was to survey the knowledge, practice and guideline use of dietitians working in ALS/MND centres/clinics across England, Wales, Northern Ireland (EWNI) and Canada. Dietetic contact details were obtained from the Motor Neurone Disease Association (MNDA) and the ALS Society of Canada (ALSSC) websites. Telephone interviews were conducted with 23 dietitians using a standardized questionnaire. Multi-disciplinary team membership was high (78%). Only 22% dietitians had >4-years experience in ALS/MND care. Dietitians reported using body weight, percentage weight loss (PWL) and body mass index (BMI) to assess nutritional status. Equations used to estimate energy and protein requirements differed. Most frequent dietary advice was high calorie, texture modification and prescription nutritional supplements. Artificial nutrition and hydration (ANH) was discussed when patients developed dysphagia, energy intake was inadequate, weight loss of 10% or forced vital capacity (FVC) was reduced. A percutaneous endoscopic gastrostomy (PEG) service was available at all clinics/centres. Nutritional assessment techniques and dietary advice should be standardized. Dietetic collaboration at national and international level is recommended to reduce professional isolation. Training and support in ALS/MND nutrition should be made available as part of post-dietetic registration. Further dietetic research is required to stimulate nutritional care.

  3. Analysis on energy consumption of drying process for dried Chinese noodles

    International Nuclear Information System (INIS)

    Wang, Zhenhua; Zhang, Yingquan; Zhang, Bo; Yang, Fuguang; Yu, Xiaolei; Zhao, Bo; Wei, Yimin

    2017-01-01

    Highlights: • Energy analysis of a tunnel dryer for dried Chinese noodles is completed. • Energy saving performance of dryers with different inlet air was compared. • MND was developed and evaluated, and the efficiency and throughput was improved. - Abstract: Drying is an important operation during the production of dried Chinese noodles, and the energy consumption from drying accounts for approximately 60% of the total energy consumption during the manufacturing process. To investigate the energy consumption and throughput of dryers for dried Chinese noodles, experiments were conducted using a new 130-m long tunnel dryer with two lines of noodles (ND) and an old 60-m long tunnel dryer with five lines of noodles (OD). The energy saving effects of a modified new 130-m long tunnel dryer (MND), which was only modified through the inclusion of automatic control for temperature and humidity without any modifications to the oil heater or ND dryer structure, were also compared. The energy saving effect was determined from the enthalpy difference between the inlet and outlet humid air of the ND and MND. Finally, the MND was found to be better than ND in terms of energy efficiency and throughput, and trends for the future of noodle drying were discussed.

  4. Electrospinning of Nanodiamond-Modified Polysaccharide Nanofibers with Physico-Mechanical Properties Close to Natural Skins

    Directory of Open Access Journals (Sweden)

    Mina Mahdavi

    2016-07-01

    Full Text Available Electrospinning of biopolymers has gained significant interest for the fabrication of fibrous mats for potential applications in tissue engineering, particularly for wound dressing and skin regeneration. In this study, for the first time, we report successful electrospinning of chitosan-based biopolymers containing bacterial cellulous (33 wt % and medical grade nanodiamonds (MND (3 nm; up to 3 wt %. Morphological studies by scanning electron microscopy showed that long and uniform fibers with controllable diameters from 80 to 170 nm were prepared. Introducing diamond nanoparticles facilitated the electrospinning process with a decrease in the size of fibers. Fourier transform infrared spectroscopy determined hydrogen bonding between the polymeric matrix and functional groups of MND. It was also found that beyond 1 wt % MND, percolation networks of nanoparticles were formed which affected the properties of the nanofibrous mats. Uniaxial tensile testing of the woven mats determined significant enhancement of the strength (from 13 MPa to 25 MP by dispersion of 1 wt % MND. The hydrophilicity of the mats was also remarkably improved, which was favorable for cell attachment. The water vapor permeability was tailorable in the range of 342 to 423 µg·Pa−1·s−1·m−1. The nanodiamond-modified mats are potentially suitable for wound healing applications.

  5. Electrospinning of Nanodiamond-Modified Polysaccharide Nanofibers with Physico-Mechanical Properties Close to Natural Skins

    Science.gov (United States)

    Mahdavi, Mina; Mahmoudi, Nafiseh; Rezaie Anaran, Farzad; Simchi, Abdolreza

    2016-01-01

    Electrospinning of biopolymers has gained significant interest for the fabrication of fibrous mats for potential applications in tissue engineering, particularly for wound dressing and skin regeneration. In this study, for the first time, we report successful electrospinning of chitosan-based biopolymers containing bacterial cellulous (33 wt %) and medical grade nanodiamonds (MND) (3 nm; up to 3 wt %). Morphological studies by scanning electron microscopy showed that long and uniform fibers with controllable diameters from 80 to 170 nm were prepared. Introducing diamond nanoparticles facilitated the electrospinning process with a decrease in the size of fibers. Fourier transform infrared spectroscopy determined hydrogen bonding between the polymeric matrix and functional groups of MND. It was also found that beyond 1 wt % MND, percolation networks of nanoparticles were formed which affected the properties of the nanofibrous mats. Uniaxial tensile testing of the woven mats determined significant enhancement of the strength (from 13 MPa to 25 MP) by dispersion of 1 wt % MND. The hydrophilicity of the mats was also remarkably improved, which was favorable for cell attachment. The water vapor permeability was tailorable in the range of 342 to 423 µg·Pa−1·s−1·m−1. The nanodiamond-modified mats are potentially suitable for wound healing applications. PMID:27399726

  6. Electrospinning of Nanodiamond-Modified Polysaccharide Nanofibers with Physico-Mechanical Properties Close to Natural Skins.

    Science.gov (United States)

    Mahdavi, Mina; Mahmoudi, Nafiseh; Rezaie Anaran, Farzad; Simchi, Abdolreza

    2016-07-07

    Electrospinning of biopolymers has gained significant interest for the fabrication of fibrous mats for potential applications in tissue engineering, particularly for wound dressing and skin regeneration. In this study, for the first time, we report successful electrospinning of chitosan-based biopolymers containing bacterial cellulous (33 wt %) and medical grade nanodiamonds (MND) (3 nm; up to 3 wt %). Morphological studies by scanning electron microscopy showed that long and uniform fibers with controllable diameters from 80 to 170 nm were prepared. Introducing diamond nanoparticles facilitated the electrospinning process with a decrease in the size of fibers. Fourier transform infrared spectroscopy determined hydrogen bonding between the polymeric matrix and functional groups of MND. It was also found that beyond 1 wt % MND, percolation networks of nanoparticles were formed which affected the properties of the nanofibrous mats. Uniaxial tensile testing of the woven mats determined significant enhancement of the strength (from 13 MPa to 25 MP) by dispersion of 1 wt % MND. The hydrophilicity of the mats was also remarkably improved, which was favorable for cell attachment. The water vapor permeability was tailorable in the range of 342 to 423 µg·Pa(-1)·s(-1)·m(-1). The nanodiamond-modified mats are potentially suitable for wound healing applications.

  7. Ungari ja eesti kõrvallauset kõrvutav väitekiri / János Pusztay

    Index Scriptorium Estoniae

    Pusztay, János, 1948-

    2014-01-01

    Arvustus: Tiina Rüütmaa. Kontrastiivne ülevaade kõneviisisüsteemist ungari ja eesti kõrvallauses. Tartu : Tartu Ülikooli Kirjastus, 2014. (Dissertationes philologiae Uralicae Universitatis Tartuensis ; 13)

  8. Ruti raamat ja Jaakobi redel / Anu Saluäär

    Index Scriptorium Estoniae

    Saluäär, Anu, 1948-

    2006-01-01

    Arvustus: Ruti raamat : artikleid, lugusid ja mälestusi : pühendusteos Rutt Hinrikusele : 7.05.2006 / [koostanud Sirje Olesk ja Janika Kronberg ; toimetanud Tiina Saluvere]. Tartu : Eesti Kirjandusmuuseum, 2006

  9. Kuni 21. III on Tartu Kunstimajas vaadata Eesti Nahakunstnike Liidu näitust "Nahk on ruumis"

    Index Scriptorium Estoniae

    2004-01-01

    Kujundaja Tea Tammelaan. Osalevad Tiiu Tulev, Pille Kivihall, Rete Kalder, Ulla Torop, Tiina Piisang, Rutt Maantoa jt. Eksponeeritakse ka jaapanlannast animatsioonikunstniku Maya Jonesho eesti köitekunstnikega koos tehtud filmi

  10. Data Redistribution through MY NASA DATA: Striving to bring authentic NASA data into education

    Science.gov (United States)

    Lewis, P. M.; Oostra, D.; Oots, P.; Chambers, L. H.; Moore, S.; Crecelius, S.; Taylor, J.

    2012-12-01

    The Mentoring and inquirY using NASA Data on Atmospheric and Earth science for Teachers and Amateurs (MY NASA DATA or MND) project was launched in 2004 to bring authentic data into K-12 education. The MND website features a Live Access Server (LAS), an open source tool which allows users to customize data sets to suit their individual needs, choosing from among 200 global Level 3 data sets. Approximately 120 lesson plans that utilize the available parameters are offered to help teachers and students get started with data exploration. Grade appropriate data documentation is also provided (with continual efforts to improve it to better meet the needs of this target audience). Through inquiry and lesson utilization, educators have several connection points to the data. As classrooms shift to problem-based and inquiry learning, the need for a data visualizer/server increases. Through numerous and growing connections to NASA satellite missions, and with access to data as a built-in feature, MND effectively fills this niche to provide a first level of data re-use that is friendly to the K-12 community. Offering a wide variety of data sets allows MND to support many science topics within the K-12 curriculum while extending the use of scientific data from NASA Earth science satellites. Lessons, created by educators across the country, allow MND to connect with the classroom teacher and to meet their data needs. As technology continues to evolve, a second level of data re-use becomes both interesting and possible. Thus, the MND team is now exploring new web and mobile platforms that can be built and distributed on an accelerated time cycle to keep up with information technology developments. With implementation of these new platforms come challenges in promoting new items to the education community, the public, and other potential users. Included in the list of challenges are: ever-evolving technology, prediction of the market, web/mobile platforms, and time-to-market for

  11. Killustatud toetusvõimalused panevad ettevõtja eri asutuste vahet jooksma / Merike Lees

    Index Scriptorium Estoniae

    Lees, Merike, 1976-

    2004-01-01

    Ettevõtluse Arendamise Sihtasutus, Põllumajanduse Registrite ja Informatsiooni Amet, konsultatsioonifirma BDA Estonia ning maakondlikud arenduskeskused jagavad toetusvõimaluste kohta erinevat informatsiooni. Kommenteerivad Kadri Ugand, Piret Arusaar, Heli Raamets ja Tiina Tarma

  12. Rutiinivabad reklaamikatlad : jänkudest, kaladest, lauajalgpallist ja golfist rääkimata / Maris Takk

    Index Scriptorium Estoniae

    Takk, Maris

    2009-01-01

    Reklaamibüroo Tank kontorist endise Baltika õmblustsehhi ruumides (sisearhitekt Tiina Teng-Tamme). Reklaamibüroo Age McCann bürooruumidest Rotermanni kvartali Jahulaos (arhitekt Tomomi Hayashi, sisearhitekt Kerli Lepp)

  13. ÜRO Lastefond toetab Memme Musi eest võitlejaid / Sirje Pärismaa

    Index Scriptorium Estoniae

    Pärismaa, Sirje, 1958-

    2003-01-01

    Riigikogu liige, UNICEF-i Eesti president Elle Kull ning haridus- ja teadusministeeriumi järelevalvetalituse peainspektor Tiina Peterson kohtusid Räpina vallavanema Inge Hirmoga, kes on lasteaia Memme Musi sulgemise poolt

  14. [Marge Rennit. Eesti muuseumid / Estonian museums] / Tapio Mäkeläinen

    Index Scriptorium Estoniae

    Mäkeläinen, Tapio

    2009-01-01

    Tutvustus: Eesti muuseumid = Estonian museums / [Eesti Muuseumiühing ; koostaja Marge Rennit ; tõlkija Tiina Mällo ; toimetaja Ivi Tammaru ; eessõna: Piret Õunapuu ; kujundaja Marek Allvee]. Tallinn : Oomen, 2008

  15. Fine 5 kolib Kumu lavale

    Index Scriptorium Estoniae

    2006-01-01

    Kumu kunstimuuseumi auditooriumis toimub 21. veebruaril Fine 5 kaasaegse tantsu etendus "Panus". Esinevad Tiina Ollesk, Irina Pähn, žonglöör Dimitri Kruus, disainer Rain Saukas ja muusik Mattias Siitan

  16. Fine 5 tantsib Bachi järgi

    Index Scriptorium Estoniae

    2016-01-01

    Tantsuteater Fine 5 toob lavale lavastuse "HTK ehk hästi treenitud klaviir". Teos on loodud J.S. Bachi "Hästitempereeritud klaviiri" (HTK) esimese osa muusikale. Koreograafid Tiina Ollesk ja Renee Nõmmik

  17. Fine 5 hoiab tantsu taset kõrgel / Anu Jürisson

    Index Scriptorium Estoniae

    Jürisson, Anu, 1977-

    2015-01-01

    Eesti teatri aastaauhindade galal tantsuauhinna pälvinud tantsuteatri Fine 5 lavastusest "...and Blue", selgitusi jagavad tantsuteatri lavastajad-koreograafid Renee Nõmmik ja Tiina Ollesk. Ka Eesti professionaalse nüüdistantsu hetkeseisust

  18. Vana vimm lõi Maltal välja / Katrin Pauts

    Index Scriptorium Estoniae

    Pauts, Katrin, 1977-

    2003-01-01

    President Arnold Rüütli Malta riigivisiidi ajal ütles presidendi protokolliülem Andrei Birov välisministeeriumi protokolliosakonna juhatajale Tiina Nirgile "Fuck you!". Riigivisiit Malta Vabariiki 1.-3.10.2003

  19. Vanad ja noored koos - kas pereidüll või tülide tallermaa / Tea Raidsalu ; kommenteerinud Meelike Saarna

    Index Scriptorium Estoniae

    Raidsalu, Tea

    2016-01-01

    Mitme põlvkonna kooselamise plussidest ja miinustest. Selgitusi jagavad ka Tallinna Ülikooli Humanitaarteaduste instituudi vanemteadur Marju Kõivupuu ja Tallinna Ülikooli Eesti Demograafia keskuse nooremteadur ja SHARE Eesti projektijuht Tiina Tambaum

  20. "Las näitlejannad mängivad. Ülevoolavalt" / Ott Karulin

    Index Scriptorium Estoniae

    Karulin, Ott, 1980-

    2009-01-01

    Rakvere Teatri lavastusest Jean Genet "Toatüdrukud", lavastaja Hendrik Toompere, kunstnik Ervin Õunapuu, osatäitjad Ülle Lichtfeldt, Tiina Mälberg ja Anneli Rahkema. Esietendus 5. juunil Rakvere Pangamajas

  1. Relationships between myonuclear domain size and fibre properties in the muscles of Thoroughbred horses.

    Science.gov (United States)

    Kawai, M; Kuwano, A; Hiraga, A; Miyata, H

    2010-11-01

    The myonuclear domain (MND) is the region of cytoplasm governed by a single myonucleus. Myonuclear domain size is an important factor for muscle fibre plasticity because each myonucleus has limitations in the capacity of protein synthesis. Previous studies have demonstrated that differences in MND size exist in different fibre types in several species, including horses. To understand the basic mechanism of muscle plasticity, the relationships between MND size, muscle fibre type population and metabolic properties of skeletal muscles throughout the whole body in Thoroughbred horses were examined. Post mortem samples were taken from 20 muscles in 3 Thoroughbred horses aged 3-5 years of age. Fibre type population was determined on serial cross sections of each muscle sample, stained for monoclonal antibodies to each myosin heavy chain isoform. Oxidative (succinic dehydrogenase; SDH) and glycolytic (phosphofructokinase; PFK) enzyme activities were determined spectrophotometrically in each muscle sample. Furthermore, 30 single fibres were isolated from each muscle under stereomicroscopy and then fibre volume and myonuclear number for a given length analysed under confocal microscopy. The MND size of each single fibre was measured after normalisation of sarcomere length to 2.8 µm by staining with membrane-specific dye. Immunohistochemical staining indicated that soleus, vastus lateralis and gluteus medius muscles had the highest percentage of type I, IIa and IIx muscle fibre, respectively. Biochemical analysis indicated highest activities of SDH and PFK in diaphragm and longissimus lumborum muscles, respectively. MNDs were largest in the splenius muscle and smallest in the soleus and masseter muscles. Myonuclear domain size is significantly related to type I muscle fibre population, but not to SDH activities of the muscles. The MND size of muscle fibre depends on fibre type population rather than mitochondrial enzyme activities. © 2010 EVJ Ltd.

  2. EBSCO infopäev Tallinnas / Marika Meltsas

    Index Scriptorium Estoniae

    Meltsas, Marika

    2008-01-01

    16. aprillil 2008 toimus Tallinnas EBSCO (Elton B. Stephens Company) infopäev, kus maailma suurim elektrooniliste ja trükiajakirjade vahendaja tutvustas oma tooteid ja teenuseid Eesti raamatukogudele. Kommentaar korraldajalt Tiina Nurmilt

  3. Edasi loodusesse! Aga kuhu? / Riina Oruaas

    Index Scriptorium Estoniae

    Oruaas, Riina

    2007-01-01

    Tantsulavastustest: Oksana Titova, Päär Pärenson ja Juhan Ulfsak "Roots", Kaja Kanni sooloetendus "There are Laika dogs living in Estonia", Tiina Mölder, Kaja Kann ja Bush Hartshor "Naine ja Hunt"

  4. Treeneri abiga edukaks / Kärt Ulman

    Index Scriptorium Estoniae

    Ulman, Kärt

    2007-01-01

    Coach ehk isiklik nõustaja on pühendunud oma kliendile, tagab tema arengu ja parema toimetuleku. Kommenteerivad Judith F. Chusid, Arthur Clancy, Asko Talu, Tiina Merkuljeva. Lisa: Coachingþu rahvusvaheline taust

  5. Kolmesaja aasta tagune kroonika sai raamatuks / Meeli Pärtelpoeg

    Index Scriptorium Estoniae

    Pärtelpoeg, Meeli, 1965-

    2006-01-01

    Rmt.: Jõelähtme kirik ja kogudus 18. sajandi esimesel poolel. Pastor Heinrich Christopher Wrede ja tema ametijärglaste kroonikamärkmed / transkribeerinud, tõlkinud ja kommenteerinud Tiina Kala. Tallinn : Muinsuskaitseamet, 2006

  6. Eesti ropendavad diplomaadid

    Index Scriptorium Estoniae

    2003-01-01

    Presidendi kantselei protokolliülem Andrei Birov ütles president Arnold Rüütli Malta riigivisiidi ajal välisministeeriumi protokolliosakonna juhataja Tiina Nirgile "Fuck you!". Riigivisiit Malta Vabariiki 1.-3.10.2003

  7. Koolisõidust Valgevenes / Eva-Maria Vint-Warmington

    Index Scriptorium Estoniae

    Vint-Warmington, Eva-Maria

    2013-01-01

    Ratsaspordi korraldusest Valgevenes, Valgevene Vabariiklikust Olümpia Ratsaspordi ja Hobusearetuskeskusest ehk Ratomka ratsakeskusest ning seal toimunud CDI3* / CDIJ / CDIYH võistlustest, kus osalesid ka Eesti sportlased Dina Ellermann ja Tiina Kuusman

  8. A metabolomic comparison of mouse models of the Neuronal Ceroid Lipofuscinoses

    Energy Technology Data Exchange (ETDEWEB)

    Salek, Reza M.; Pears, Michael R. [University of Cambridge, Department of Biochemistry and Cambridge Systems Biology Centre (United Kingdom); Cooper, Jonathan D. [King' s College London, Pediatric Storage Disorders Laboratory, Department of Neuroscience, Institute of Psychiatry (United Kingdom); Mitchison, Hannah M. [Royal Free and University College Medical School, Department of Paediatrics and Child Health (United Kingdom); Pearce, David A. [Sanford School of Medicine of the University of South Dakota, Department of Pediatrics (United States); Mortishire-Smith, Russell J. [Johnson and Johnson PR and D (Belgium); Griffin, Julian L., E-mail: jlg40@mole.bio.cam.ac.uk [University of Cambridge, Department of Biochemistry and the Cambridge Systems Biology Centre (United Kingdom)

    2011-04-15

    The Neuronal Ceroid Lipofuscinoses (NCL) are a group of fatal inherited neurodegenerative diseases in humans distinguished by a common clinical pathology, characterized by the accumulation of storage body material in cells and gross brain atrophy. In this study, metabolic changes in three NCL mouse models were examined looking for pathways correlated with neurodegeneration. Two mouse models; motor neuron degeneration (mnd) mouse and a variant model of late infantile NCL, termed the neuronal ceroid lipofuscinosis (nclf) mouse were investigated experimentally. Both models exhibit a characteristic accumulation of autofluorescent lipopigment in neuronal and non neuronal cells. The NMR profiles derived from extracts of the cortex and cerebellum from mnd and nclf mice were distinguished according to disease/wildtype status. In particular, a perturbation in glutamine and glutamate metabolism, and a decrease in {gamma}-amino butyric acid (GABA) in the cerebellum and cortices of mnd (adolescent mice) and nclf mice relative to wildtype at all ages were detected. Our results were compared to the Cln3 mouse model of NCL. The metabolism of mnd mice resembled older (6 month) Cln3 mice, where the disease is relatively advanced, while the metabolism of nclf mice was more akin to younger (1-2 months) Cln3 mice, where the disease is in its early stages of progression. Overall, our results allowed the identification of metabolic traits common to all NCL subtypes for the three animal models.

  9. A metabolomic comparison of mouse models of the Neuronal Ceroid Lipofuscinoses

    International Nuclear Information System (INIS)

    Salek, Reza M.; Pears, Michael R.; Cooper, Jonathan D.; Mitchison, Hannah M.; Pearce, David A.; Mortishire-Smith, Russell J.; Griffin, Julian L.

    2011-01-01

    The Neuronal Ceroid Lipofuscinoses (NCL) are a group of fatal inherited neurodegenerative diseases in humans distinguished by a common clinical pathology, characterized by the accumulation of storage body material in cells and gross brain atrophy. In this study, metabolic changes in three NCL mouse models were examined looking for pathways correlated with neurodegeneration. Two mouse models; motor neuron degeneration (mnd) mouse and a variant model of late infantile NCL, termed the neuronal ceroid lipofuscinosis (nclf) mouse were investigated experimentally. Both models exhibit a characteristic accumulation of autofluorescent lipopigment in neuronal and non neuronal cells. The NMR profiles derived from extracts of the cortex and cerebellum from mnd and nclf mice were distinguished according to disease/wildtype status. In particular, a perturbation in glutamine and glutamate metabolism, and a decrease in γ-amino butyric acid (GABA) in the cerebellum and cortices of mnd (adolescent mice) and nclf mice relative to wildtype at all ages were detected. Our results were compared to the Cln3 mouse model of NCL. The metabolism of mnd mice resembled older (6 month) Cln3 mice, where the disease is relatively advanced, while the metabolism of nclf mice was more akin to younger (1-2 months) Cln3 mice, where the disease is in its early stages of progression. Overall, our results allowed the identification of metabolic traits common to all NCL subtypes for the three animal models.

  10. Kuidas möödus 2012. aasta komplekteerimises? / Külli Karu, Rutt Enok, Kaili Õunapuu-Seidelberg ... [jt.

    Index Scriptorium Estoniae

    2013-01-01

    Vastavad Külli Karu Tallinna Keskraamatukogust, Rutt Enok Harju Maakonnaraamatukogust, Kaili Õunapuu-Seidelberg Lääne-Virumaa Keskraamatukogust, Tiina Talvet Rapla Keskraamatukogust, Toivo Ärtis Kambja raamatukogust ning kultuuriministeeriumi raamatukogunõunik Meeli Veskus

  11. Fine 5 Eesti tantsuväljal / Iiris Viirpalu

    Index Scriptorium Estoniae

    Viirpalu, Iiris, 1992-

    2017-01-01

    Nüüdistantsuteatril Fine 5 täitub tänavu 25. tegutsemisaasta. Fine 5 käekirjast. Vestlusest Fine 5 tantsuteatri ja -kooli kauaaegsete kunstiliste juhtide Renee Nõmmiku ja Tiina Olleskiga Eesti tantsukunstist

  12. Leil on kõva! : dokumentaalne lugemisdraama neljas pildis. Volüüm 2 / Madis Jürgen

    Index Scriptorium Estoniae

    Jürgen, Madis, 1962-

    1999-01-01

    Miks tahavad poliitikud Sauna tänavale teatrit? Tegelased: Krista Siilats, Jaan Tamm, Signe Kivi, Jüri Kuuskemaa, Margus Allikmaa, Krista Kodres, Kalev Kallo, Tiina Mägi, Silvi Lindma-Pihlak, Eino Baskin, Mart Laar.

  13. TiSSA eelkonverents doktorantidele Tallinnas / Koidu Saame

    Index Scriptorium Estoniae

    Saame, Koidu

    2010-01-01

    Tallinna Ülikoolis toimunud TiSSA doktorantide eelkonverentsist 22.-24. aug. 2010.a. Doktorantide ettekannetest. Esinesid: Hans-Uwe Otto, Andriy Yuryev, Tiina Naarits, Ivar Tröner, Koidu Saame, Maija Jäppinen, Janissa Miettinen

  14. Sissejuhatus sõnavõlur Tolkieni juurde / Neeme Korv

    Index Scriptorium Estoniae

    Korv, Neeme, 1974-

    2003-01-01

    Carpenter, Humphrey. J. R. R. Tolkien : elulugu / inglise keelest tõlkinud Tiina Randus.Tallinn : Tänapäev, 2002 ; Day, David. Tolkieni entsüklopeedia / inglise keelest tõlkinud Marek Laane. Tallinn : Varrak, 2002

  15. Номинанты на премию Oscar в мире моды / Бритт Розен

    Index Scriptorium Estoniae

    Розен, Бритт, 1968-

    2009-01-01

    Eesti moeauhinna Kuldnõel nominendid 2008 on moekunstnikud Tiina Talumees, Liivia Leškin, Liisi Eesmaa ja Aldo Järvsoo. Nominentide uuemast moeloomingust. Kuldnõela galaetendus toimub 6. märtsil 2009 Viru keskuses

  16. Suicide in patients with motor neuron disease

    DEFF Research Database (Denmark)

    Bak, Søren; Stenager, E N; Stenager, Egon

    1994-01-01

    The aim of the present study was to assess, through an epidemiological study, whether suicide risk is increased in patients with motor neuron disease (MND). The study involved 116 patients with MND. In the study period 92 patients died, 47 males and 45 females. No patients committed suicide....... The number of expected suicides was 0.27 for males and 0.12 for females, a total of 0.38. The difference between observed and expected suicides was not statistically significant for males and females....

  17. Quantification of brain metabolites in amyotrophic lateral sclerosis by localized proton magnetic resonance spectroscopy

    DEFF Research Database (Denmark)

    Gredal, O; Rosenbaum, S; Topp, S

    1997-01-01

    We performed proton magnetic resonance spectroscopy (1H-MRS) in patients with motor neuron disease (MND) to determine the absolute in vivo concentrations in the brain of the metabolites N-acetyl aspartate (NAA), choline (Cho), and creatine (Cr/PCr). We examined the spectra acquired from a 20 x 20 x...... subjects. We estimated the concentrations of the metabolites using the water signal as an internal standard. The concentrations of Cho and Cr/PCr in both brain regions, as well as the concentration of NAA in the cerebellum, were unaltered in the MND patients compared with the controls. Only MND patients...... with both upper and lower motor neuron signs had a significantly decreased concentration of NAA (9.13 +/- 0.28 mM, mean +/- SEM) in the primary motor cortex when compared with healthy controls (10.03 +/- 0.22 mM). In conclusion, the slightly decreased concentration of NAA in the primary motor cortex from...

  18. Direct Sensing of Nutrients via a LAT1-like Transporter in Drosophila Insulin-Producing Cells

    Directory of Open Access Journals (Sweden)

    Gérard Manière

    2016-09-01

    Full Text Available Dietary leucine has been suspected to play an important role in insulin release, a hormone that controls satiety and metabolism. The mechanism by which insulin-producing cells (IPCs sense leucine and regulate insulin secretion is still poorly understood. In Drosophila, insulin-like peptides (DILP2 and DILP5 are produced by brain IPCs and are released in the hemolymph after leucine ingestion. Using Ca2+-imaging and ex vivo cultured larval brains, we demonstrate that IPCs can directly sense extracellular leucine levels via minidiscs (MND, a leucine transporter. MND knockdown in IPCs abolished leucine-dependent changes, including loss of DILP2 and DILP5 in IPC bodies, consistent with the idea that MND is necessary for leucine-dependent DILP release. This, in turn, leads to a strong increase in hemolymph sugar levels and reduced growth. GDH knockdown in IPCs also reduced leucine-dependent DILP release, suggesting that nutrient sensing is coupled to the glutamate dehydrogenase pathway.

  19. Finger extension weakness and downbeat nystagmus motor neuron disease syndrome: A novel motor neuron disorder?

    Science.gov (United States)

    Delva, Aline; Thakore, Nimish; Pioro, Erik P; Poesen, Koen; Saunders-Pullman, Rachel; Meijer, Inge A; Rucker, Janet C; Kissel, John T; Van Damme, Philip

    2017-12-01

    Disturbances of eye movements are infrequently encountered in motor neuron diseases (MNDs) or motor neuropathies, and there is no known syndrome that combines progressive muscle weakness with downbeat nystagmus. To describe the core clinical features of a syndrome of MND associated with downbeat nystagmus, clinical features were collected from 6 patients. All patients had slowly progressive muscle weakness and wasting in combination with downbeat nystagmus, which was clinically most obvious in downward and lateral gaze. Onset was in the second to fourth decade with finger extension weakness, progressing to other distal and sometimes more proximal muscles. Visual complaints were not always present. Electrodiagnostic testing showed signs of regional motor axonal loss in all patients. The etiology of this syndrome remains elusive. Because finger extension weakness and downbeat nystagmus are the discriminating clinical features of this MND, we propose the name FEWDON-MND syndrome. Muscle Nerve 56: 1164-1168, 2017. © 2017 The Authors Muscle & Nerve Published by Wiley Periodicals, Inc.

  20. Efficacy of kinesiology tape versus postural correction exercises on neck disability and axioscapular muscles fatigue in mechanical neck dysfunction: A randomized blinded clinical trial.

    Science.gov (United States)

    El-Abd, Aliaa M; Ibrahim, Abeer R; El-Hafez, Haytham M

    2017-04-01

    Mechanical neck dysfunction (MND), with axioscapular muscles fatigue, is highly prevalent worldwide. While postural correction is commonly used for its treatment, efficacy of kinesiology tape (KT) has received considerable attention. To determine the effectiveness of KT versus correction exercises on neck disability, and axioscapular muscles fatigue in MND patients. 46 MND patients were randomly assigned into 1 of 2 groups receiving 4 weeks treatment of either KT or correction exercises. Neck disability and axioscapular muscles fatigue as median frequency of electromyography (EMG-MF) were measured pre and post treatment. Group-by-time interaction was not significant in the multivariable test. Post hoc tests revealed that KT produced more disability reduction than the postural exercises. However, there was no significant interaction for EMG-MF. KT has been found to be more effective than postural exercises to reduce neck disability. However, both modalities have similar effects to reduce axioscapular muscles fatigue. Copyright © 2016 Elsevier Ltd. All rights reserved.

  1. Riho Pätsi Koolimuusika Fond austab uusi laureaate / Inge Raudsepp

    Index Scriptorium Estoniae

    Raudsepp, Inge

    2009-01-01

    4. septembril saavad Riho Pätsi Koolimuusika Fond laureaaditiitli muusikaõpetaja Koidu Ilmjärv, tšellopedagoog Mart Laas, helilooja Mart Siimer, dirigent Jüri-Ruut Kangur, Tallinna Ülikooli muusikaosakonna juhataja Tiina Selke

  2. Hans Christian Andersen 200

    Index Scriptorium Estoniae

    2005-01-01

    Hollandi lasteraamatute autorist ja illustraatorist Max Velthuijs'ist (1923-2005). H.C. Anderseni 200. sünniaastapäevale pühendatud lasteraamatunäitusest Rahvusraamatukogus. Eksponeeritakse ka Tiina Reinsalu akvarelle raamatule "Ööbik"

  3. Bingo! / Tiina Tammet

    Index Scriptorium Estoniae

    Tammet, Tiina, 1971-

    2005-01-01

    Diarmuid Gavin Design'i kujundatud Rahvuslik Loteriiaed (The National Lottery Garden) Chelsea aiandusnäitusel. Rohelisi toone täiendavad värvilised metallist pallid. Kõrgete metallvarbade otsas moodustavad pallid värvika õielaine, aia eesosas saab neist pergola. Pallid vooderdavad ka mullikujulist aiapaviljoni. Aia teostas Sean Cunningham. 3 värv. ill

  4. Asepresident / Tiina Kaalep

    Index Scriptorium Estoniae

    Kaalep, Tiina, 1964-

    2003-01-01

    Ilmunud ka: Den za Dnjom 4. juuli lk. 12-13, Hiiu Leht 8. juuli lk. 4-5. Autor kirjutab presidendi kantseleis valitsevast õhkkonnast ja suhetest töötajate ning kantselei direktori Tarmo Männi vahel

  5. Blogid Rapla maakonna rahvaraamatukogudes / Maie Jakobson

    Index Scriptorium Estoniae

    Jakobson, Maie

    2009-01-01

    Rapla maakonna raamatukoguhoidjate arvamus ajaveebi pidamisest, eelnevatest koolitustest. Arvamust avaldavad: Helve Lehtmaa Laukna raamatukogust, Ilme Säde Käru ramatukogust, Tiina Vaher ja Maie Kalmiste Kehtna raamatukogust, Irma Robam Vahastu raamatukogust ning Mariina Madisson Lelle raamatukogust

  6. Nii loodi fond Mälestus / Linda Järve

    Index Scriptorium Estoniae

    Järve, Linda, 1946-

    2003-01-01

    12. dets. 2002.a. kirjutasid sihtasutuse Eesti Rahvuskultuuri Fond nõukogu esimees Eri Klas ja Tallinna noorte klubi Kodulinn juhataja Tiina Mägi alla lepingule, millega pandi alus Eesti Rahvuskultuuri Fondi uuele nimelisele allfondile Mälestus

  7. [Raamat] / Kaja Tiisel

    Index Scriptorium Estoniae

    Tiisel, Kaja

    2007-01-01

    Rets. rmt.: Jõelähtme kirik ja kogudus 18. sajandi esimesel poolel. Pastor Heinrich Christopher Wrede ja tema ametijärglaste kroonikamärkmed. Transkribeerinud, tõlkinud ja kommenteerinud Tiina Kala. Tallinn : Muinsuskaitseamet, 2006. 420 lk.

  8. The National Representation Beauty Contest / Karolina Łabowicz-Dymanus

    Index Scriptorium Estoniae

    Łabowicz-Dymanus, Karolina

    2011-01-01

    Näitus "The Art of Estonia - Adapting Modernity / Provocations and Confrontations" Szczecini Rahvusmuuseumis kuni 27.veebr. 2011 ja Varssavi Rahvusmuuseumis kuni 04. juulini 2011. Kumu Kunstimuuseumi korraldatud näituse kuraatorid Tiina Abel ja Eha Komissarov

  9. Therapeutical aspect of trichomoniasis

    Directory of Open Access Journals (Sweden)

    Vukićević Jelica

    2003-01-01

    Full Text Available Trichomoniasis is frequent, parasitic and sexually transmitted infection of genitourinary tract. It is treated by metronidazole (5-nitroimidazole according to protocol recommended by Center for Disease Control (CDC formerly called: Communicable Disease Center [19]. The resistance of Trichomonas vaginalis (TV strains to metronidazole (MND was described in USA in 1960, and later on in many European countries [8, 9, 10, 11, 12, 13]. In these cases, due to persistent trichomonas infection, it is necessary to repeat MND treatment with moderate modification of dose and/or length of its application. Nevertheless, oncogenic and toxic effects of MND have to be taken into consideration. OBJECT The aim of this study was to investigate and analyze the incidence of TV in STD and lower susceptibility of certain TV strains to MND were analyzed. MATERIAL AND METHODS In three-year period (1999-2001 612 patients (244 females and 368 males suspected of STD were examined clinically and microbiologically at the Institute of Dermatovenereology in Belgrade. The patients detected for TV were treated according to CDC protocol. The affected were considered cured if there was no manifest clinical infection, and no TV verified by microbiological test. Results TV was isolated in 216 patients (35.29 % of all subjects. Trichomonas infection was found in 90 (36.88 % out of 244 tested females and in 126 (32.34 % of 368 males. Clinically manifested infection, with extensive urethral and vaginal secretion, was recorded in 161 patients, while the asymptomatic form was found in 55 subjects. This result indicates the predominance of manifested trichomonas infections (75.54 % of cases. The difference of distribution of clinical forms of trichomoniasis, in relation to sex, was not statistically significant (c2=0.854; p>0.05. The patients with verified trichomonas infection were treated by metronidazole according to CDC protocol. The recommended therapeutical scheme consisted of three

  10. Fine 5 lavastab Venemaal

    Index Scriptorium Estoniae

    2013-01-01

    Tantsuteatru Fine 5 koreograafid Tiina Ollesk ja Rene Nõmmik toovad Jekaterinburgis välja lavastuse "... and Red", esitajaks Venemaa nimekas nüüdistantsutrupp Provintsialnõje Tantsõ. Lavastuses kõlab Taavo Remmeli kontrabassiimprovisatsioon "12.12.2006"

  11. Kui koolist saab villand / Aivi Pargi

    Index Scriptorium Estoniae

    Pargi, Aivi, 1950-

    2004-01-01

    Mitme riigi pedagoogid leiavad, et põhikoolieas kooli pooleli jätmine on uus sotsiaalne nähtus, mida saab ennetada õpetajatele uusi oskusi andes ning vanematega koostööd tehes. Kommenteerivad Riina Veidenbaum, Tiina Kivirand

  12. Volta alale kerkib uhke elurajoon / Ann-Marii Nergi

    Index Scriptorium Estoniae

    Nergi, Ann-Marii

    2011-01-01

    Põhja-Tallinnas asuva Volta kvartali detailplaneeringu eskiis on linnavalitsuses kooskõlastatud. Volta kvartali ideekonkursi võitis Soome arhitektibüroo AW². Detailplaneeringu koostaja, ConArte AB juhatuse liikme Tiina Vilbergi ja AS-i Volta tegevdirektori Aivar Reiviku kommentaarid

  13. Swiss Property kontor = Offices of Swiss Property / kommenteerinud Tõnis Sõõrumaa

    Index Scriptorium Estoniae

    2015-01-01

    Swiss Property kontoriruumid Tallinnas Rotermanni 8. Sisekujunduse autorid Kätlin Ölluk, Tiina Kesküla, Katy Seppel, Aet Kiivet, Liina Rohtlaan, Marita Mätas, Lilian Esing, Kristin Boginski (Swiss Property); arhitektid Yoko Azukawa, Hanno Grossschmidt, Tomomi Hayashi

  14. Eesti oopereid Nargen-festivalil / Evi Arujärv

    Index Scriptorium Estoniae

    Arujärv, Evi, 1953-

    2011-01-01

    Timo Steineri ooperist "Kask pead", libretist Maarja Kangro, lavastaja Mart Koldits, dirigent Tõnu Kaljuste ja Anti Marguste mini mono-ooperite A. H. Tammsaare, August Kitzbergi ja Oskar Lutsu tekstidele "Andreses monoloogid", "Tiina monoloogid", "Arno monoloogid", dirigent Tõnu Kaljuste,

  15. 90-aastane Tallinna Polütehnikum - ainus omataoline / Sirje Tohver

    Index Scriptorium Estoniae

    Tohver, Sirje

    2005-01-01

    Polütehnikumi vilistlastest õpetajate (Heiki Tähis, Andres Ojalill, Jüri Jakubovitš, Hugo Tartlan, Hergi Kruusimaa, Tiina Karja, Priit Kalman, Ardi Priks, Jaan Kuus, Jüri Puhang, Vello Vanem, Rein Kask, Kalle Sammal, Ain Saaret) meenutusi

  16. Koolis möödunud festival eelistas lapsi / Merit Kask, Liisi Poll

    Index Scriptorium Estoniae

    Kask, Merit

    2003-01-01

    Lõppenud Pärnu XVII dokumentaal- ja antropoloogiafilmide festivalist. Lisaks avaldavad oma arvamust rahvusvahelise žürii esimees John Russel Taylor, žürii liige Tiina Lokk ja eesti dokumentaalfilmide žürii esimees Tõnis Kask. Lisatud auhinnasaajate nimekiri

  17. Arstide koolitus vaakumis / Triin Tabur

    Index Scriptorium Estoniae

    Tabur, Triin

    2014-01-01

    Arstide täienduskoolituse fondi tulumaksusoodustustega ühenduste nimekirjast välja jätmine on arstide erialase täienduskoolituse välismaal jätnud stipendiumiteta. Selgitusi jagavad Katrin Rehemaa, Margus Viigimaa, Tiina Sats ja Toomas Pruunsild

  18. Mozarti kadunud autograaf võtab publiku ees kuju / Riina Luik

    Index Scriptorium Estoniae

    Luik, Riina, 1962-

    2011-01-01

    Eesti Ajaloomuuseumis asuvast Mozarti autograafist 27. klaverikontserdi B-duur käsikirjast. Tiina Õuna uurimistööst Mozarti noodikäsikirja teekonna Viinist Tallinna uurimisel. 30. septembril Estonia kontserdisaalis toimuvast kontserdist, kus ettekandele tuleb ka 27. klaverikontsert

  19. Moodsad näidisasumid : Weissenhof & Maasika-Vaarika : näitus Eesti Arhitektuurimuuseumis 21. 04.-20. 05. 2001 / Triin Ojari

    Index Scriptorium Estoniae

    Ojari, Triin, 1974-

    2001-01-01

    Karin Kirschi ja Tiina Tammeti koostatud näituse põhjal 1927. a. Stuttgarti rajatud Weissenhofi väikemajade elamurajoonist (arhitektid Walter Gropius, Bruno Taut, Le Corbusier jt.) ja 1931-1932 Tallinnasse ehitatud Maasika-Vaarika tänava asumit

  20. Tallinlased kostitavad Euroopa filmitähti / Andreas Sepp

    Index Scriptorium Estoniae

    Sepp, Andreas

    2010-01-01

    Eesti-poolne korraldaja Ave Ungro projektist "Kino kiikab kööki", mille raames kostitavad Tallinna kodud Euroopa Filmiakadeemia gala külalisi. EFA külalist võõrustavast kunstnik Andres Lõost ja kino "Sõprus" loovjuhist Tiina Savist

  1. "Ega need loteriivõidud meile taevast alla ei kuku" : Eesti Kooli jõulupidu pole enem mägede taga / Katrin Käärik ; foto: Katrin Käärik

    Index Scriptorium Estoniae

    Käärik, Katrin, 1950-

    2006-01-01

    lapsevanemad Tiina Baugus-Hörnstam, Aime Mölder ja Mart Klaar on need, kes on võtnud Stockholmi Eesti Kooli jõululoterii korraldamise töö ja rõõmu endi kanda. Annetamise võimalustest ja tähtaegadest

  2. Noorteprogramm "Angelika! Angelika!" / Helemall Piirfeldt

    Index Scriptorium Estoniae

    Piirfeldt, Helemall

    2005-01-01

    2005. a. mais Kadrioru Kunstimuuseumis näituse "Šveitsi muusa. Angelika Kauffmann (1741-1807)" raames toimunud noorteprogrammist "Angelika! Angelika!", mida juhendasid moekunstnik Sirje Märjamaa ja muuseumipedagoog Helemall Piirfeldt. Moeetenduse lavastas Tiina Makarov, konsultant oli grimmikunstnik Anu Konze

  3. Fine5 tantsuteater võitis Vitebskis teise preemia

    Index Scriptorium Estoniae

    2006-01-01

    22. - 26. XI Valgevenes toimunud kaasaegse koreograafia konkursil "International Festival of Modern Choreography" võitsid Laura Kvelstein ja Dmitri Kruus lühiteostega "1 spot, 2 shadows" teise preemia. Konkursi raames toimunud meistriklasse juhendas Fine5 koreograaf Tiina Ollesk

  4. Roman Toi kaks suurt armastust : muusika ja Eesti / Elle Puusaag ; foto: V. Sarapuu

    Index Scriptorium Estoniae

    Puusaag, Elle, 1945-2017

    2007-01-01

    Toronto Eesti Maja kristallsaalis toimunud pidulikust õhtust 5. detsembril: maestro Roman Toi mälestusteraamatu esitlusest. Rets. rmt.: Toi, Roman. Kaunimad laulud pühendan sull' : Roman Toi mälestused/toimetaja Tiina Sarv. Toronto : Viljandi : T. Sarv, 2007

  5. Tallinna Tehnikakõrgkooli Arhitektuuri Instituudi rahvusvaheline töötuba 8.-12. september 2008

    Index Scriptorium Estoniae

    2009-01-01

    Töötoa "Linnamaastik / Roheline Tallinn" teemad: "Tuukri park", "Vanalinna bastionite rohevöönd", "Teatriväljak", juhendajad: maastikuarhitekt Günter Nagel (Saksamaa), arhitektid Irina Raud ja Katrin Vannas, maastikuarhitekt Tiina Tuulik . Osalesid 4. kursuse arhitektuuri eriala tudengid

  6. Moodulitest komplekteeritav diivan Black = A modular sofa called Black

    Index Scriptorium Estoniae

    2007-01-01

    Autor Tiina Mang pälvis diivanikomplekti Black eest Eesti Sisearhitektide Liidu 2006. a. esemepreemia. T. Mangist, objektid, kuhu on valitud T. Mangi projekteeritud mööblit, näitused. 3 värv. vaadet, foto T. Mangist

  7. В Нарве можно будет посмотреть удостоенный эстонской театральной премии спектакль / Рене Ныммик ; интервьюировала Тийа Линнард

    Index Scriptorium Estoniae

    Ныммик, Рене

    2015-01-01

    Narva kultuurimajas Rugodiv näeb Fine5 tantsuteatri lavastust "...and blue", mis võitis tänavu Eesti teatriauhinna. Etenduse koreograafideks ja lavastajateks on Tiina Ollesk ja Rene Nõmmik, keda on palutud lavastama ka Venemaale. Intervjuu Rene Nõmmikuga

  8. Narvas näeb Eesti tantsuauhinna võitnud tantsulavastust / Rene Nõmmik ; intervjueerinud Tiia Linnart

    Index Scriptorium Estoniae

    Nõmmik, Rene, 1962-

    2015-01-01

    Narva kultuurimajas Rugodiv näeb Fine5 tantsuteatri lavastust "...and blue", mis võitis tänavu Eesti teatriauhinna. Etenduse koreograafideks ja lavastajateks on Tiina Ollesk ja Rene Nõmmik, keda on palutud lavastama ka Venemaale. Intervjuu Rene Nõmmikuga

  9. Fonoloogiast piiblitõlkeni. Mati Hindi juubelikogumik / Reili Argus

    Index Scriptorium Estoniae

    Argus, Reili, 1967-

    2012-01-01

    Tutvustus: Pühendusteos emeriitprofessor Mati Hindi 75. sünnipäevaks / koostanud ja toimetanud Reili Argus, Annika Hussar ja Tiina Rüütmaa. Tallinn : Tallinna Ülikool, 2012. (Tallinna Ülikooli eesti keele ja kultuuri instituudi toimetised ; 14)

  10. Monkey Business toetab shimpansit / Sergo Selder

    Index Scriptorium Estoniae

    Selder, Sergo

    2004-01-01

    Moeturg teeb show'd Reval Park Hotelli & Casino heategevusüritusel. Osalevad tuntud tegijad Tiina Talumees Pärni, Triin Randloo, Kris Soonik ja noored moekunstnikud Triin Kärblane, Janina Pasti, Jana Einard. Kampaania on Tallinna loomaaia shimpansi Pino toetuseks

  11. Prediction of cleavage crack propagation and arrest in a nuclear pressure vessel steel (16MND5) under thermal shock

    International Nuclear Information System (INIS)

    Yang, Xiaoyu

    2015-01-01

    The purpose of this PhD study is to predict the propagation and arrest of cleavage cracks in a French PWR vessel steel (16MND5). This is accomplished through use of a local criterion based on the critical stress calculated ahead of crack tip. Previous work has shown that fracture mechanism was cleavage associated with the ductile shear zone between the different planes of cracking. Thus, the critical stress at crack tip depends on stain rate. This thesis consists of numerical optimization, identification and validation of a local criterion based on experiments which have complex thermomechanical loads. The criterion accounts for various crack paths, deepening the knowledge about micro mechanisms during crack propagation in order to justify the established criterion. Criterion identification was carried out by using numerical simulations of tension tests performed on CT (Compact Tension) specimens at four different temperatures (-150 C, -125 C, -100 C and -75 C). The eXtended Finite Element Method (X-FEM) was used in CAST3M FE software to model dynamic crack propagation and arrest. The analysis results in 2D and 3D showed that the critical stress at crack tip increased with the inelastic strain rate. Therefore, a criterion based on the critical stress was established. An analytical model was developed to justify the identified criterion. The critical stress given by the local criterion was considered as the sum of the critical cleavage stress and the stress generated by the deformation of ligaments behind the crack tip. In order to quantify this phenomenon, measurements of ligaments' characteristics have been performed on fracture surfaces and on cross-sections of the specimens. The stress profile of the crack lips generated by ligaments was calculated by modeling of multi-cracks on specimen's cross-section. The contribution of stress generated by ligaments to the critical stress at crack tip was obtained with this method, and then the analytical model of

  12. Eesti tants ühines Dogma-manifestiga / Tiit Tuumalu

    Index Scriptorium Estoniae

    Tuumalu, Tiit, 1971-

    2001-01-01

    "1=3 õige või vale" (idee autor ja lavastaja Jarmo Karing), kunstnik Liina Tepand, esietendus 1. märtsil Tartu Teatrilaboris; "1973. Võrrand kolme muutuja ja ühe puudujaga" ( idee autor Tiina Mölder), esietendus 1. aprillil Mustpeade Majas

  13. Lugupeetud emakeeleõpetaja! / Martin Ehala

    Index Scriptorium Estoniae

    Ehala, Martin, 1963-

    2006-01-01

    Tutvustatakse eesti keele õpikuid: Ehala, Martin. Eesti keele struktuur. Tallinn, 2001 ; Ehala, Martin. Kirjutamise kunst. Tallinn, 2000 ; Ehala, Martin. Eesti kirjakeel. Tallinn, 2002 ; Madisso, Maia. Keele- ja tekstiharjutusi abiturientidele. Tallinn, 2002 ; Ehala, Martin ; Veismann, Tiina jt. Noor keelekasutaja. Tallinn, 2005

  14. Eesti Lähimineviku Okupatsioonide Muuseumi arhitektuurivõistlus : okupatsiooni igaveseks jäädvustamiseks = Architectural Competition of the Museum of Recent Past Occupations in Estonia : for Eternal Remembrance of the Occupation / Leonhard Lapin

    Index Scriptorium Estoniae

    Lapin, Leonhard, 1947-

    2001-01-01

    Zürii koosseis, võistlusest, võidutööst. Preemiad: I - Indrek Peil, Siiri Vallner; II - Tiina Teng, Peeter Loo; III - Reio Avaste; ostud - Andres Kask ning Markus Kaasik, Kalle Komissarov, Andres Ojari, Indrek Tiigi ja Ilmar Valdur. 5 ill.

  15. Neoimpressionismi klassikud Kumus / Ragne Nukk

    Index Scriptorium Estoniae

    Nukk, Ragne, 1984-

    2010-01-01

    Näitus "Neoimpressionismi jälgedes. Mägi ja Finch" Kumu Kunstimuuseumis 12. septembrini 2010. Kuraator Tiina Abel, kujundaja Inga Heamägi. Eksponeeritakse Soome muuseumide kogudesse kuuluvaid prantsuse maalikunstnike töid ja eesti kunstnike teoseid. Lühidalt neoimpressionismist

  16. Pärnu muuseumis näeb vammuseid ja pesu / Karin Klaus

    Index Scriptorium Estoniae

    Klaus, Karin

    2009-01-01

    Näitus "Meie vammus" Pärnu Muuseumis, koostaja Ülli Kont. Viljandi Muuseumi rändnäitus "Need" Pärnu Muuseumis, koostajad Tiina Jürgen, Ebe-Triin Arros, Lüüli Kiik, Herki Helves. Näitused on avatud 12. septembrini

  17. Voltage-Gated Potassium Channel Antibodies in Slow-Progression Motor Neuron Disease.

    Science.gov (United States)

    Godani, Massimiliano; Zoccarato, Marco; Beronio, Alessandro; Zuliani, Luigi; Benedetti, Luana; Giometto, Bruno; Del Sette, Massimo; Raggio, Elisa; Baldi, Roberta; Vincent, Angela

    2017-01-01

    The spectrum of autoimmune neurological diseases associated with voltage-gated potassium channel (VGKC)-complex antibodies (Abs) ranges from peripheral nerve disorders to limbic encephalitis. Recently, low titers of VGKC-complex Abs have also been reported in neurodegenerative disorders, but their clinical relevance is unknown. The aim of the study was to explore the prevalence of VGKC-complex Abs in slow-progression motor neuron disease (MND). We compared 11 patients affected by slow-progression MND with 9 patients presenting typical progression illness. Sera were tested for VGKC-complex Abs by radioimmunoassay. The distribution of VGKC-complex Abs was analyzed with the Mann-Whitney U test. The statistical analysis showed a significant difference between the mean values in the study and control groups. A case with long-survival MND harboring VGKC-complex Abs and treated with intravenous immunoglobulins is described. Although VGKC-complex Abs are not likely to be pathogenic, these results could reflect the coexistence of an immunological activation in patients with slow disease progression. © 2016 S. Karger AG, Basel.

  18. Attitudes towards euthanasia and physician-assisted suicide among Pakistani and Indian doctors: A survey

    Directory of Open Access Journals (Sweden)

    Syed Qamar Abbas

    2008-01-01

    Full Text Available Aim: This study attempts to assess the attitude of Pakistani and Indian doctors to euthanasia and physician-assisted suicide. Methods: We used a questionnaire survey that included one case history of a patient with cancer and another of one suffering from motor neurone disease (MND. Results: Fifty-two of 100 doctors from Pakistan returned the completed questionnaires. Eight of the 52 (15.3% doctors agreed with the concept of euthanasia being an acceptable option for the patient with MND. Six of the 52 (11.5% supported a similar approach for the cancer patient. From India, 60/100 doctors returned the completed questionnaires. Sixteen of the 60 (26.6% doctors supported euthanasia as an option for the patient with MND whereas 15 (25% supported a similar option for the cancer patient. Conclusion: We conclude that only a minority of the doctors support euthanasia. This group belongs to a younger age group. In Pakistan, they were more likely to be males. The religion of the doctors did not appear to be a determining factor.

  19. Esimene erialane täienduskoolitus toimus sada aastat tagasi / Krista Talvi

    Index Scriptorium Estoniae

    Talvi, Krista, 1948-

    2013-01-01

    18. aprillil 2013 tähistati TÜ Viljandi Kultuuriakadeemias seminariga "Koolitajalt koolitajale" 100. aasta möödumist erialase täienduskoolituse algusest ning ERÜ koolituse toimkonna 25. aastapäeva

  20. A self-care, problem-solving and mindfulness intervention for informal caregivers of people with motor neurone disease: A pilot study.

    Science.gov (United States)

    Ugalde, Anna; Mathers, Susan; Hennessy Anderson, Nicole; Hudson, Peter; Orellana, Liliana; Gluyas, Cathy

    2018-04-01

    Informal caregivers of people with motor neurone disease (MND) take on an extensive role. Caregivers are at increased risk of experiencing psychological distress and burden, yet, there is a lack of intervention programmes to support them. The aim of this study was to investigate the feasibility and acceptability of a therapeutic group intervention promoting self-care, problem-solving and mindfulness to informal caregivers of people with MND. Pilot study that utilised a one-arm pre- and post-design. Acceptability of the intervention was assessed 2 weeks post intervention with a questionnaire designed specifically for this study. Feasibility was assessed with consent, adherence and reasons for non-participation, refusal and attrition. Participants completed baseline and follow-up (6-week post intervention) questionnaires for psychological morbidity, burden, problem-solving, mindfulness and preparedness. Settings/participants: Caregivers of people with a diagnosis of MND within the past 12 months who were 18 years or older; who could speak, read and write in English and who were attending a progressive neurological diseases clinic were eligible. A total of 13 caregivers participated in one of three group intervention sessions which were focused on self-care, problem-solving and mindfulness. The intervention appeared to be feasible and acceptable. All participants stated that they would recommend the intervention to others. The group format appeared to be highly valued. There was no significant change in measures between pre-intervention and 6 weeks post intervention. This pilot serves as an initial step for examining interventions for MND caregivers, with the hope of identifying effective, efficient and sustainable strategies to best support this group.

  1. Predictive value of general movements' quality in low-risk infants for minor neurological dysfunction and behavioural problems at preschool age.

    Science.gov (United States)

    Bennema, Anne N; Schendelaar, Pamela; Seggers, Jorien; Haadsma, Maaike L; Heineman, Maas Jan; Hadders-Algra, Mijna

    2016-03-01

    General movement (GM) assessment is a well-established tool to predict cerebral palsy in high-risk infants. Little is known on the predictive value of GM assessment in low-risk populations. To assess the predictive value of GM quality in early infancy for the development of the clinically relevant form of minor neurological dysfunction (complex MND) and behavioral problems at preschool age. Prospective cohort study. A total of 216 members of the prospective Groningen Assisted Reproductive Techniques (ART) cohort study were included in this study. ART did not affect neurodevelopmental outcome of these relatively low-risk infants born to subfertile parents. GM quality was determined at 2 weeks and 3 months. At 18 months and 4 years, the Hempel neurological examination was used to assess MND. At 4 years, parents completed the Child Behavior Checklist; this resulted in the total problem score (TPS), internalizing problem score (IPS), and externalizing problem score (EPS). Predictive values of definitely (DA) and mildly (MA) abnormal GMs were calculated. DA GMs at 2 weeks were associated with complex MND at 18 months and atypical TPS and IPS at 4 years (all ppredictive value of DA GMs at 2 weeks were rather low (13%-60%); specificity and negative predictive value were excellent (92%-99%). DA GMs at 3 months occurred too infrequently to calculate prediction. MA GMs were not associated with outcome. GM quality as a single predictor for complex MND and behavioral problems at preschool age has limited clinical value in children at low risk for developmental disorders. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  2. Pritjagatelnõje aromatõ zolotoi oseni / Britt Rosen

    Index Scriptorium Estoniae

    Rosen, Britt, 1968-

    2008-01-01

    2008. a. sügise moeparfüümidest. Naisteparfüümi Lancome Magnifique loojad on Olivier Cresp ja Jacques Cavallier. Dsquared esimese naistelõhna She Wood autorid on kanada moedisainerid kaksikvennad Dean ja Dan Caten. Kommenteerivad Anu Merila ja Tiina Talumees

  3. Suvised mööndused kontoririietele / Sigrid Tappo

    Index Scriptorium Estoniae

    Tappo, Sigrid

    2005-01-01

    Audiitorteenuseid pakkuva AS-i Deloitte Audit Eesti töötajate suvisest kontoririietusest. Eesti Kunstiakadeemia moedisaini osakonna dotsent Jüri Siim ning Estonian Business Schooli suhtekorralduse ja ärijuhtimise õppejõud Tiina Tshatshua tutvustavad nõudeid suvisele töörõivastusele

  4. 101 riigikogulast said valijalt ehmatava liputervituse / Tuuli Koch

    Index Scriptorium Estoniae

    Koch, Tuuli

    2006-01-01

    Ilmunud ka: Postimees : na russkom jazõke 4. sept. lk. 4. Valija Tiina Talts saatis presidendivalimiste esimese päeva hommikul parlamendiliikmetele kirja, mille juurde oli ümber disainitud Eesti lipp. Vastused saatsid neli saadikut, nende hulgas Mait Klaassen, Jaak Allik, Janno Reiljan

  5. Blogi näitab vingemaid kontoreid / Kristiina Viiron

    Index Scriptorium Estoniae

    Viiron, Kristiina, 1971-

    2010-01-01

    Veebiagentuuri Okia Blogi inspiratsioonirubriigi "Disainisahtel" artikliseeria pealkirjaga "Inspireeriv töökeskkond" tutvustab välismaiseid büroode sisekujundusi, reklaamiagentuuri Tank ja veebiagentuuri Okia ühist kontorit Tallinnas Baltika kvartalis (sisekujundus Tiina Teng) ja teisi loova sisekujundusega büroosid Eestis

  6. Peterburis maandusid tulnukad - Rasmus Merivoo juhatab vägesid! / Kristiina Davidjants

    Index Scriptorium Estoniae

    Davidjants, Kristiina, 1974-

    2008-01-01

    Peterburis Eesti-Vene koostöös sündiva mängufilmi "Buratino" võtetel. Režissöör on Rasmus Merivoo, nimiosas Mikk Nurga, Carabas Barabasi rollis Jaan Rekkor, operaator Aleksandr Kornejev, Eestipoolsed produtsendid Mati Sepping ja Tiina Lokk

  7. Hudozhnik i jego dom

    Index Scriptorium Estoniae

    2004-01-01

    Näituse "Kunstnik ja tema kodu. C. T. von Neffi kunstikogu Piira ja Muuga mõisast" raames Väliskunsti Muuseumis toimunud konverentsi "19. sajandi keskpaiga kunstiruum" ettekannetest. Esinesid Jevgenia Kiritshenko, Juri Gudõmenko, Ants Hein, Kadi Polli, Veronika Bogdan, Ingrida Raudsepa, Tiina Abel

  8. Täna toimub Kadrioru lossis väliskunsti muuseumis...

    Index Scriptorium Estoniae

    2004-01-01

    Näituse "Kunstnik ja tema kodu. C. T. von Neffi kunstikogu Piira ja Muuga mõisast" raames toimuva ettekannete päeva "19. sajandi keskpaiga kunstiruum" kava. Esinevad Jevgenia Kiritshenko, Juri Gudõmenko, Ants Hein, Kadi Polli, Veronika Bogdan, Ingrida Raudsepa, Tiina Abel

  9. Avastatud klaas / Kai Lobjakas

    Index Scriptorium Estoniae

    Lobjakas, Kai, 1975-

    2006-01-01

    Euroopa kõrgkoolide klaasieriala üliõpilaste tööde näitus "Discovery / Avastusretk" Kullo galeriis kuni 19. V. Rahvusvahelise ürituse korraldajaks oli EKA klaasikunsti osakond eesotsas Mare Saare ja Tiina Sarapuga. Pikemalt Ave Maseri tööst "Maandumine"

  10. Koopia. Koopia? Koopia! / Anne Untera

    Index Scriptorium Estoniae

    Untera, Anne, 1951-

    2006-01-01

    Eesti Kunstimuuseumi näitusest "Meistriteoste lummus. Koopia Eestis 19. sajandil" ja satelliitnäitusest "Laurits ja Laurentsius. Meistriteoste varjus". 3. aprillil 2006. a. toimunud konverentsist - Dorothee von Hellermanni, Mai Levini, Tiina-Mall Kreemi, Juta Keevalliku, Inge Kuke ja Bärbel Kovalevski ettekannetest

  11. Kas internet muudab meid rumalamaks? / Liis Kängsepp

    Index Scriptorium Estoniae

    Kängsepp, Liis, 1981-

    2012-01-01

    Raamatust: Carr, Nicholas. Triiv madalikule : mida Internet meie ajuga teeb / tõlkija Tiina Randus. Tallinn : Äripäev, 2012. (Äripäeva raamat). Ka intervjuu Tallinna Ülikooli dotsendi Kristjan Pordiga raamatus esitatud väidetest interneti mõjust inimesele

  12. Alfred Kongo, intiimse maalilaadi meister / Juta Kivimäe

    Index Scriptorium Estoniae

    Kivimäe, Juta, 1952-

    2001-01-01

    Alfred Kongost, tema loomingust. A. Kongo 95. sünniaastapäeva tähistav näitus Adamson-Ericu muuseumis 10. X-11. XI ja 9. XI toimub mälestusteõhtu. Näha saab Tiina Pargi 1984. a. filmi A. Kongost

  13. Kas töötukassa soovitab lapsed CV-st välja jätta? / Mari Kodres

    Index Scriptorium Estoniae

    Kodres, Mari

    2010-01-01

    Karjäärinõustaja Tiina Saare väitel selgus vestlusest töötukassa ühe konsultandiga, et töötukassa klientidel soovitatakse lapsi elulookirjeldusse mitte märkida. Töötukassa nõustamisteenuste ala teenustejuhi Lana Randaru selgitus

  14. Kunst ja käsitöö Eesti hapras filmiühiskonnas ehk Kes määrab rahva maitse / Tarmo Teder

    Index Scriptorium Estoniae

    Teder, Tarmo, 1958-

    2002-01-01

    Probleemidest eesti filmikunstis ja -tootmises kõnelevad produtsent ja režissöör Peeter Urbla, filmikriitik Tiina Lokk, režissöör, stsenarist ja filmikriitik Andres Maimik ning režissöörid Marko Raat ja Rainer Sarnet

  15. Numerical modelling of Charpy-V notch test by local approach to fracture. Application to an A508 steel in the ductile-brittle transition range; Modelisation de l'essai Charpy par l'approche locale de la rupture. Application au cas de l'acier 16MND5 dans le domaine de transition

    Energy Technology Data Exchange (ETDEWEB)

    Tanguy, B

    2001-07-15

    Ferritic steels present a transition of the rupture mode which goes progressively of a brittle rupture (cleavage) to a ductile rupture when the temperature increases. The following of the difference of the transition temperature of the PWR vessel steel by the establishment of toughness curves makes of the Charpy test an integrating part of the monitoring of the French PWR reactors. In spite of the advantages which are adapted to it in particular its cost, the Charpy test does not allow to obtain directly a variable which characterizes a crack propagation resistance as for instance the toughness used for qualifying the mechanical integrity of a structure. This work deals with the establishment of the through impact strength-toughness in the transition range of the vessel steel: 16MND5 from a non-empirical approach based on the local approach of the rupture. The brittle rupture is described by the Beremin model (1983), which allows to describe the dispersion inherent in this rupture mode. The description of the brittle fissure is carried out by the GTN model (1984) and by the Rousselier model (1986). This last model has been modified in order to obtain a realistic description of the brittle damage in the case of fast solicitations and of local heating. The method proposed to determine the parameters of the damage models depends only of tests on notched specimens and of the inclusion data of the material. The behaviour is described by an original formulation parametrized in temperature which allows to describe all the tests carried out in this study. Before using this methodology, an experimental study of the behaviour and of the rupture modes of the steel 16MND5 has been carried out. From the toughness tests carried out in quasi-static and dynamical conditions, it has been revealed that this steel does not present important unwedging of its toughness curve due to the velocity effect. In the transition range, local heating of about 150 C have been measured in the root

  16. Molecular nonlinear dynamics and protein thermal uncertainty quantification

    Science.gov (United States)

    Xia, Kelin; Wei, Guo-Wei

    2014-01-01

    This work introduces molecular nonlinear dynamics (MND) as a new approach for describing protein folding and aggregation. By using a mode system, we show that the MND of disordered proteins is chaotic while that of folded proteins exhibits intrinsically low dimensional manifolds (ILDMs). The stability of ILDMs is found to strongly correlate with protein energies. We propose a novel method for protein thermal uncertainty quantification based on persistently invariant ILDMs. Extensive comparison with experimental data and the state-of-the-art methods in the field validate the proposed new method for protein B-factor prediction. PMID:24697365

  17. 运动神经元病%Motor Neuron Disease

    Institute of Scientific and Technical Information of China (English)

    蒋雨平

    2014-01-01

    Motor neuron disease (MND) represents a group of sporadic or genetic neurodegenerative diseases which principally affect the motor neurons and result in progressive paralysis and death. The epidemiology, genetics, clinical manifestation, diagnostic criteria of MND were reviewed.%运动神经元病是一组散发或遗传的神经变性病。主要累及运动神经元,病程进展而死亡。文中就其临床表现和诊断标准、流行病学和遗传学进行综述。

  18. Kuidas tõlkida Kumu-hoonet kunsti keelde ehk kunstiehitus versus kunst = How to translate the Kumu building into the language of art or artistic architecture versus art / Liina Siib

    Index Scriptorium Estoniae

    Siib, Liina

    2006-01-01

    Kumu näitusekujundaja tähelepanekuid maja ja ekspositsiooni vahelistest seostest. Kumu põhiekspositsioonide kujundajad: Liina Siib (Eesti kunst 18. sajandist kuni 1944. aastani, kuraator Tiina Abel) ning Terje Kallast ja Urmas Luure (Eesti kunst 1945-1991, kuraatorid Eha Komissarov ja Kädi Talvoja)

  19. Mida sina täna õppisid? / Veikko Täär, Ain Aaviksoo, Ingrid Tõniste ... [jt.

    Index Scriptorium Estoniae

    2012-01-01

    Oma õppimistest ja tulevikuplaanidest räägivad näitleja ja ettevõtja Veikko Täär, tervishoiuteadlane Ain Aaviksoo, tegevjuht Ingrid Tõniste, TV3 avalike suhete juht ja uudisteankur Anneli Adermann, arenduskonsultant Anu Puusaag, personaaltreener Katrin Pärt ja loodusarst Tiina Keldrima

  20. Veerandfinalist Kaia Kanepi : hoidke mulle veel kord pöialt! / Jaan Jürine

    Index Scriptorium Estoniae

    Jürine, Jaan, 1946-

    2008-01-01

    Täna kordub French Openil seitsme aasta tagune noorte finaal Kaia Kanepi ja Svetlana Kuznetsovaga. Kommenteerivad suusakahevõistluse olümpiavõitja Allar Levandi, kümnevõistluse olümpiavõitja Riigikogu liige Erki Nool ja TC Reval Ladiesi tenniseklubi juht Tiina Mõis

  1. Kasutamata potensiaal saatkondade arhitektuuris / Andro Mänd

    Index Scriptorium Estoniae

    Mänd, Andro

    2008-01-01

    USA ja Põhjamaade suunast saatkonnahoonete arhitektuuris. Soome saatkonnahoonest (Mikko Heikkinen, Markku Komonen, 1994) Washingtonis, Põhjamaade (Taani, Islandi, Norra, Rootsi, Soome) saatkonnakompleksist (Alfred Berger, Tiina Parkkinen, 1999) Berliinis, Rootsi saatkonnahoonest (Gert Wingardh, Tomas Hansen, 2006) Washingtonis. Eesti uutest Riia ja Pekingi saatkonnahoonetest, ruumiprogrammist, konkursi tingimustest

  2. Moda vernulas v Tallin / Marina Poltavtseva

    Index Scriptorium Estoniae

    Poltavtseva, Marina

    2005-01-01

    Tallinnas Viru Keskuses toimuvast moeürituste sarjast FIBIT. Keskne sündmus on Kuldnõela nominentide Katrin Kuldma, Tiina Talumehe, Thea Pilveti ja Evelin Lille kollektsioonide esitamine. Lisas "Primetshai marku!" juttu moekunstnik Oksana Tanditi uuest kollektsioonist, mida näidatakse ka Viru keskuses

  3. Gericault, Monet ja Dufy Kumus / Harry Liivrand

    Index Scriptorium Estoniae

    Liivrand, Harry, 1961-

    2009-01-01

    Prantsusmaalt Lille'i Kunstimuuseumi kogudest pärinev 19. sajandi ja 20. sajandi I poole maastikumaali väljapanek "Normandia maalijad" Kumu Kunstimuuseumis 16. oktoobrist 10. jaanuarini 2010. Näituse koostaja Alain Tapié ja kuraator Tiina Abel. Nimetatud eksponeeritavate tööde autoreid

  4. Mida teha varemetega? / Epp Lankots

    Index Scriptorium Estoniae

    Lankots, Epp, 1976-

    2002-01-01

    1. ja 2. IV Tallinnas toimunud rahvusvahelise konverentsi "Varemed. Vahemerest Läänemereni" teisest konverentsipäevast, mis keskendus varemetele Tallinnas (Jaani seek, Rotermanni kvartal, Harju tänav, tselluloosikombinaat). Tiina-Mall Kreemi eestvedamisel Väliskunsti muuseumi korraldatud noortenäitusest "Elu varemete keskel"

  5. INES 2000 ja Läänemere ülikool / Annika Tenno

    Index Scriptorium Estoniae

    Tenno, Annika

    2000-01-01

    Läänemere Ülikooli programmiga (The Baltic University Programme) seotud õppejõududel oli võimalus osaleda INES 2000 konverentsil Stockholmis 14.-18. juunil̀2000, peateemaks "Challenges for Science and Engineering in the 21st Century". Tallinna Pedagoogikaülikooli esindajaks oli Tiina Elvisto

  6. Samblikud astusid sammu õppurile lähemale / Juhani Püttsepp

    Index Scriptorium Estoniae

    Püttsepp, Juhani, 1964-

    2010-01-01

    Rahvusvahelise haridusprojekti KeyToNature raames valminud e-samblikumäärajast Android OSil töötavatele mobiiltelefonidele "Eesti epifüütsed suursamblikud", mille loojateks on Tartu ülikooli botaanikud Tiina Randlane ja Andres Saag ning IT-spetsialist Marko Peterson koos itaalia kolleegidega

  7. 16. oktoobril 2005 Kõik valima! : [luuletused

    Index Scriptorium Estoniae

    2005-01-01

    Sisu: Inna Feldbach. "Tegin vahtralehdedele põletusmatust..." ; Katrin Väli. Ülesanne: vrais ou faut ; Karl Martin Sinijärv. Monkey Doodle ehk Kommarid? Kahju... ; Andra Teede. Suurte siniste silmade maa ; Tiina Saar. Valijale ; Kohutav keskerakohuke / tundmatu netifolklorist ; Julius Ürt. Etteütlus

  8. Numerical modelling of Charpy-V notch test by local approach to fracture. Application to an A508 steel in the ductile-brittle transition range; Modelisation de l'essai Charpy par l'approche locale de la rupture. Application au cas de l'acier 16MND5 dans le domaine de transition

    Energy Technology Data Exchange (ETDEWEB)

    Tanguy, B

    2001-07-15

    Ferritic steels present a transition of the rupture mode which goes progressively of a brittle rupture (cleavage) to a ductile rupture when the temperature increases. The following of the difference of the transition temperature of the PWR vessel steel by the establishment of toughness curves makes of the Charpy test an integrating part of the monitoring of the French PWR reactors. In spite of the advantages which are adapted to it in particular its cost, the Charpy test does not allow to obtain directly a variable which characterizes a crack propagation resistance as for instance the toughness used for qualifying the mechanical integrity of a structure. This work deals with the establishment of the through impact strength-toughness in the transition range of the vessel steel: 16MND5 from a non-empirical approach based on the local approach of the rupture. The brittle rupture is described by the Beremin model (1983), which allows to describe the dispersion inherent in this rupture mode. The description of the brittle fissure is carried out by the GTN model (1984) and by the Rousselier model (1986). This last model has been modified in order to obtain a realistic description of the brittle damage in the case of fast solicitations and of local heating. The method proposed to determine the parameters of the damage models depends only of tests on notched specimens and of the inclusion data of the material. The behaviour is described by an original formulation parametrized in temperature which allows to describe all the tests carried out in this study. Before using this methodology, an experimental study of the behaviour and of the rupture modes of the steel 16MND5 has been carried out. From the toughness tests carried out in quasi-static and dynamical conditions, it has been revealed that this steel does not present important unwedging of its toughness curve due to the velocity effect. In the transition range, local heating of about 150 C have been measured in the root

  9. Gurmee, kiirtoit ja koduköök läbisegi / Heie Treier

    Index Scriptorium Estoniae

    Treier, Heie, 1963-

    2006-01-01

    Rahvusvahelisest joonistuste näitusest "Improvisatsioon" Tallinna Kunstihoones. Oma töid eksponeerivad Tõnis Vint, Evald Okas, Lembit Sarapuu, Aili Vahtrapuu, Albert Gulk, Ülle Marks, Anu Kalm, Vive Tolli, Inga Heamägi, Evi Tihemets, Mare Vint, Maria-Kristiina Ulas, Kuzja Zverev, Tiina Tammetalu jt

  10. Klaas ja mõis / Maie-Ann Raun

    Index Scriptorium Estoniae

    Raun, Maie-Ann, 1938-

    2007-01-01

    Klaasikunstinäitus "Ringkäik" Albu mõisas, kuraatorid Virve Kiil, Kati Kerstna, Kairi Orgusaar. Eksponeeritakse Tiina Sarapu, Mare Saare, Eeva Käsperi, Kai Kiudsoo-Värvi, Pilvi Ojamaa, Merle Bukoveci, Kalli Seina, Viivi-Ann Keerdo, Liisi Junolaineni, Kristiina Uslari, Ivo Lille töid

  11. Kuus, kes kuidagi kokku ei saa / Veiko Märka

    Index Scriptorium Estoniae

    Märka, Veiko, 1964-

    1999-01-01

    Arvustus: Merca [Jääger, Merle]. Vana libu hommik; Ruitlane, Olavi. Inemise sisu; Contra [Konnula, Margus]. Päike ja lamp; Ilves, Aapo. Üks pedajas; Pai, Tiina. Armastab mõrvatud haldjaid; Tamme, Villu. Sorlimeki plät. Kõik : Tartu : Eesti Kostabi $eltsi Kaasaegse Kirjanduse Keskus, 1998

  12. Näitused

    Index Scriptorium Estoniae

    1998-01-01

    Rahvusraamatukogu - Eesti Vabariigi 80. aastapäevale pühendatud näitused, Kristjan Raua majamuuseum - Tiina Käeseli ehtenäitus "Traat tõmbab", Niguliste kiriku Antoniuse kabel - Sally Stuudio näitus "Vapp kohtub vapiga Nigulistes", Tervishoiumuuseum - ungari kunstniku Gyula Madarasz'i akvarellinäitus

  13. Eesti Kunstiakadeemia tootedisaini eriala magistritööde kaitsmised 3. juulil...

    Index Scriptorium Estoniae

    2001-01-01

    Kaitsmisele tulevad tööd: Liis Ira "Säästev tootearendus ja tekstiilide recycling" (juh. Tiina Laurila); Ruth-Helene Kaasiku "Energiasäästmisvõimalused välisvalgustuses" (juh. Arvo Pärenson); Maria Pukk'i "Linnainventari kohereerumine vahelduvates maastikes" - "Green Way" (juh. A. Pärenson).

  14. Enesetapp helesinisel ekraanil / Margit Tõnson

    Index Scriptorium Estoniae

    Tõnson, Margit, 1978-

    2008-01-01

    Telemängudest, televisiooni võimalikust mõjust inimeste vaimsele tervisele, emotsionaalsele heaolule. Telemängust "Tõehetk", mis ka Eestis on vaadatavuse edetabelites esikohal (Kanal 2). Oma arvamuse ütlevad artiklis "Mis sa oskad kosta?" kirjanik Jan Kaus, ajakirjanik Tiina Kaalep ja sotsioloog Airi-Alina Allaste

  15. Tantsuteater ütleb oma ruumidele hüvasti / Andres Laasik

    Index Scriptorium Estoniae

    Laasik, Andres, 1960-2016

    2011-01-01

    Tantsuteatri Fine 5 uuest tantsulavastusest "Enne kui minna, ma ütlen", mis tähistab teatri sunnitud lahkumist Tallinnas Lai t. 9 asuvatest ruumidest. Tantsuteatri Fine 5 eestvedajad Tiina Ollesk ja René Nõmmik Lai t. 9 asuva hoone seisukorrast, sinna kolimisest, teatrist, uute ruumide otsingust

  16. "The word was sung, the word was bound" / Lester Capon

    Index Scriptorium Estoniae

    Capon, Lester, 1951-

    2010-01-01

    4. rahvusvaheline köitekunsti näitus-konkurss "Scripta manent" Eesti Tarbekunsti- ja Disainimuuseumis 9. jaanuarini 2011. Köita tuli Veljo Tormise "Lauldud sõna". Jeff Clementsi, Katinka Keusi (Holland), Lolita Grabauskiene-Tarbunaite (Leedu), Tiina Piisangu, Maila Käose, Ruuda Maarandi töödest

  17. Neli vaadet banaanile / Evelin Lagle, Heili Einasto

    Index Scriptorium Estoniae

    Lagle, Evelin, 1986-

    2010-01-01

    Kahest tantsulavastusest: "Kaks naist köögis, banaanist rääkimata", koreograafid ja esitajad Kaja Lindal ja Mari Mägi, esietendus 14. oktoobril 2010 Kanuti gildi saalis ning "Neli vaadet", lavastaja Maret Mursa, tantsijad Rene Nõmmik ja Tiina Ollesk, esietendus 15. oktoobril NO99s

  18. Aldo Järvsoo: kirivööd ma ei lõigu / Tiiu Laks

    Index Scriptorium Estoniae

    Laks, Tiiu, 1984-

    2009-01-01

    Eesti 2008. aasta parim moekunstnik ja auhinna Kuldnõel omanik on Aldo Järvsoo, tema kollektsioonist "Virve". Lühidalt auhinna teiste nominentide Liisi Eesmaa, Tiina Talumehe ja Liivia Leškini kollektsioonidest. Võidukollektsiooni saab 15. märtsini vaadata Tallinna Kaubamaja Naistemaailmas paikneval näitusepinnal

  19. Naismaalijate abstraktsioon ja empaatia / Reet Varblane

    Index Scriptorium Estoniae

    Varblane, Reet, 1952-

    2003-01-01

    Tartu Kunstimajas näitus "Abstraktsioon ja empaatia. Kristiina Kaasik, Lola Liivat, Helina Loid (sünd. 1982), Tiiu Pallo-Vaik, Mall Paris, Anne Parmasto, Mari Roosvalt, Sirje Runge, Tiina Tammetalu, Margi Vähi (sünd. 1975)". Kuraator ja väljapaneku kujundaja Reet Varblane

  20. Why don't they accept non-invasive ventilation?: insight into the interpersonal perspectives of patients with motor neurone disease.

    Science.gov (United States)

    Ando, Hikari; Williams, Carl; Angus, Robert M; Thornton, Everard W; Chakrabarti, Biswajit; Cousins, Rosanna; Piggin, Lucy H; Young, Carolyn A

    2015-05-01

    Although non-invasive ventilation (NIV) can benefit survival and quality of life, it is rejected by a substantial proportion of people with motor neurone disease (MND). The aim of this study was to understand why some MND patients decline or withdraw from NIV. Nine patients with MND (male = 7, mean age = 67 years) participated in this study. These patients, from a cohort of 35 patients who were offered NIV treatment to support respiratory muscle weakness, did not participate in NIV treatment when it was clinically appropriate. Semi-structured interviews and interpretative phenomenological analysis (IPA) were employed to explore these patient's experience of MND and their thoughts and understanding of NIV treatment. Using IPA, four themes were identified: preservation of the self, negative perceptions of NIV, negative experience with health care services, and not needing NIV. Further analysis identified the fundamental issue to be the maintenance of perceived self, which was interpreted to consist of the sense of autonomy, dignity, and quality of life. The findings indicate psychological reasons for disengagement with NIV. The threat to the self, the sense of loss of control, and negative views of NIV resulting from anxiety were more important to these patients than prolonging life in its current form. These findings suggest the importance of understanding the psychological dimension involved in decision-making regarding uptake of NIV and a need for sensitive holistic evaluation if NIV is declined. Statement of contribution What is already known on this subject? Non-invasive ventilation is widely used as an effective symptomatic therapy in MND, yet about a third of patients decline the treatment. Psychological disturbance generated by NIV use leads to negative experiences of the treatment. Decision-making about treatment potentials is complex and unique to each individual affected by perceived impact of disease. What does this study add? A decision concerning

  1. Ahp2 (Hop2) function in Arabidopsis thaliana (Ler) is required for stabilization of close alignment and synaptonemal complex formation except for the two short arms that contain nucleolus organizer regions.

    Science.gov (United States)

    Stronghill, P; Pathan, N; Ha, H; Supijono, E; Hasenkampf, C

    2010-08-01

    A cytological comparative analysis of male meiocytes was performed for Arabidopsis wild type and the ahp2 (hop2) mutant with emphasis on ahp2's largely uncharacterized prophase I. Leptotene progression appeared normal in ahp2 meiocytes; chromosomes exhibited regular axis formation and assumed a typical polarized nuclear organization. In contrast, 4',6'-diamidino-2-phenylindole-stained ahp2 pachytene chromosome spreads demonstrated a severe reduction in stabilized pairing. However, transmission electron microscopy (TEM) analysis of sections from meiocytes revealed that ahp2 chromosome axes underwent significant amounts of close alignment (44% of total axis). This apparent paradox strongly suggests that the Ahp2 protein is involved in the stabilization of homologous chromosome close alignment. Fluorescent in situ hybridization in combination with Zyp1 immunostaining revealed that ahp2 mutants undergo homologous synapsis of the nucleolus-organizer-region-bearing short arms of chromosomes 2 and 4, despite the otherwise "nucleus-wide" lack of stabilized pairing. The duration of ahp2 zygotene was significantly prolonged and is most likely due to difficulties in chromosome alignment stabilization and subsequent synaptonemal complex formation. Ahp2 and Mnd1 proteins have previously been shown, "in vitro," to form a heterodimer. Here we show, "in situ," that the Ahp2 and Mnd1 proteins are synchronous in their appearance and disappearance from meiotic chromosomes. Both the Ahp2 and Mnd1 proteins localize along the chromosomal axis. However, localization of the Ahp2 protein was entirely foci-based whereas Mnd1 protein exhibited an immunostaining pattern with some foci along the axis and a diffuse staining for the rest of the chromosome.

  2. In silico analysis of β-mannanases and β-mannosidase from Aspergillus flavus and Trichoderma virens UKM1

    Science.gov (United States)

    Yee, Chai Sin; Murad, Abdul Munir Abdul; Bakar, Farah Diba Abu

    2013-11-01

    A gene encoding an endo-β-1,4-mannanase from Trichoderma virens UKM1 (manTV) and Aspergillus flavus UKM1 (manAF) was analysed with bioinformatic tools. In addition, A. flavus NRRL 3357 genome database was screened for a β-mannosidase gene and analysed (mndA-AF). These three genes were analysed to understand their gene properties. manTV and manAF both consists of 1,332-bp and 1,386-bp nucleotides encoding 443 and 461 amino acid residues, respectively. Both the endo-β-1,4-mannanases belong to the glycosyl hydrolase family 5 and contain a carbohydrate-binding module family 1 (CBM1). On the other hand, mndA-AF which is a 2,745-bp gene encodes a protein sequence of 914 amino acid residues. This β-mannosidase belongs to the glycosyl hydrolase family 2. Predicted molecular weight of manTV, manAF and mndA-AF are 47.74 kDa, 49.71 kDa and 103 kDa, respectively. All three predicted protein sequences possessed signal peptide sequence and are highly conserved among other fungal β-mannanases and β-mannosidases.

  3. Diaphragm pacing and noninvasive respiratory management of amyotrophic lateral sclerosis/motor neuron disease.

    Science.gov (United States)

    Mahajan, Kedar R; Bach, John Robert; Saporito, Lou; Perez, Nick

    2012-12-01

    Although it is known that continuous noninvasive ventilation (CNIV) can prolong life in amyotrophic lateral sclerosis/motor neuron disease (ALS/MND), in this study we explore similar claims for diaphragm pacing (DP). NIV and DP users' vital capacities (VCs) over time and duration of NIV and CNIV dependence were analyzed for 354 non-DP and 8 DP ALS/MND patients. Patients had a higher rate of monthly VC decline before NIV use (5.1 ± 7.6%) than during NIV use (2.5 ± 3.6%) (P NIV for 19.9 ± 27.6 months until tracheostomy/death, whereas 113 others used it for 10.9 ± 10.5 months until CNIV dependence for another 12.8 ± 16.2 months. After placement, 7 DP users were CNIV dependent in 8.0 ± 7.0 months, whereas 6 underwent tracheostomy/died in 18.2 ± 13.7 months. CNIV prolonged the survival of 113 of the 354 non-DP and 6 DP ALS/MND patients by 12.8 and 10.2 months, respectively. DP provided no benefit on VC or mechanical ventilation-free survival. Copyright © 2012 Wiley Periodicals, Inc.

  4. Experience of long-term use of non-invasive ventilation in motor neuron disease: an interpretative phenomenological analysis.

    Science.gov (United States)

    Ando, Hikari; Chakrabarti, Biswajit; Angus, Robert M; Cousins, Rosanna; Thornton, Everard W; Young, Carolyn A

    2014-03-01

    Although non-invasive ventilation (NIV) can promote quality of life in motor neuron disease (MND), previous studies have disregarded the impact of progression of illness. This study explored how patients' perceptions of NIV treatment evolve over time and how this was reflected in their adherence to NIV. Five patients with MND (male=4, mean age=59 years), from a bigger cohort who were prospectively followed, had multiple post-NIV semistructured interviews, covering more than 12 months, along with ventilator interaction data. The transcribed phenomenological data were analysed using qualitative methodology. Three themes emerged: experience of NIV, influence on attitudes and perceived impact of NIV on prognosis. The ventilator interaction data identified regular use of NIV by four participants who each gave positive account of their experience of NIV treatment, and irregular use by one participant who at interview revealed a negative attitude to NIV treatment and in whom MND induced feelings of hopelessness. This exploratory study suggests that a positive coping style, adaptation and hope are key factors for psychological well-being and better adherence to NIV. More studies are needed to determine these relationships.

  5. Study on antioxidant experiment on forged steel tube sheet and tube hole for steam generator

    International Nuclear Information System (INIS)

    Zong Hai; Wang Detai; Ding Yang

    2012-01-01

    Antioxidant experiment on forged steel tube sheet and tube hole for steam generator was studied and the influence of different simulated heat treatments on the antioxidant performance of tube sheet and tube hole was made. The influence of different antioxidant methods on the size of tube hole was drawn. Furthermore, the change of size and weight of 18MnD5 forged steel tube sheet on the condition of different simulated heat treatments was also studied. The analytical results have proved reference information for the use of 18MnD5 material and for key processes of processing tube hole and wearing and expanding U-style tube. (authors)

  6. Kavatsedes kaminat / Tiina Kolk

    Index Scriptorium Estoniae

    Kolk, Tiina

    2007-01-01

    AET Arhitektide arhitekt Priit Hamer kaminate paigaldamisest, avatud koldega kaminast, klaasuksega ahjust, õhkkütte- ehk malmsüdamega kaminast, gaasikaminast ja valmiskaminatest, kamina sobitumisest ruumikujundusega

  7. Tulipunktis tootekunst / Tiina Kolk

    Index Scriptorium Estoniae

    Kolk, Tiina

    2008-01-01

    Muljeid disainimessilt "100% Design London". Eesti disainiauhinna Bruno pälvisid Mare Kelpman kollektsiooniga ""Light & Stripes" ning Tarmo Luisk valgusallikaga "Led Stick". Kommenteerivad Ilona Gurjanova, Heikki Zoova, Kaire Kemp-Tishler

  8. Hullutav hortensia / Tiina Kolk

    Index Scriptorium Estoniae

    Kolk, Tiina, 1956-

    2016-01-01

    Põhja-Ameerikast ning Ida- ja Kagu-Aasiast pärit hortensia perekond on ligi 75-liigiline. Eesti aedades on levinud püstise ja koonilise õisikuga aedhortensia Hydrangea paniculata ja ümarakujulise õisikuga puishortensia Hydrangea arborescens. Vestlusest Sadevälja aiandustalu perenaise Jana Proosiga

  9. Helsingisse kunstireisile! / Tiina Kolk

    Index Scriptorium Estoniae

    Kolk, Tiina

    2016-01-01

    Soome tekstiilikunstniku Kirsti Rantaneni vaipade ja ruumiinstallatsioonide näitus Helsingi Disainimuuseumis. Itaalia maalikunstniku Amadeo Modigliani loomingu näitus Helsingis Ateneumis. Jaapani kunstniku Yayoi Kusama loomingu näitus "In Infinity" Helsingi kunstimuuseumis HAM

  10. Õigus / Tiina Kala

    Index Scriptorium Estoniae

    Kala, Tiina, 1967-

    2008-01-01

    Käsikirjalistest allikatest (Lübecki õigus = Jus Lubicense 1257 ; Lübecki õigus = Das lübische Recht 1282 ; Lübecki õigus : raehärrade valimise ja vannutamise kord = Das lübische Recht : Ordnung für die Wahl und Beeidigung der Ratsherren 13.-16. saj. ; Lübecki õigus : Tallinna privileegid : das lübische Recht : Privilegien der Stadt Reval 14. saj. ; Kuningas Magnus Erikssoni linnaõigus = Kung Magnus Erikssons stadslag 15. saj. ; Vendi linnade mereõigus = Seerecht der wendischen Städte 1482 ; Lübecki õigus = Das lübische Recht 1511) Tallinna Linnaarhiivis ja Eesti Ajaloomuuseumis

  11. Kolm põnevat raamatut / Kristiina Ehin

    Index Scriptorium Estoniae

    Ehin, Kristiina, 1977-

    2003-01-01

    Coelho, Paulo. Palverännak: maagi päevik : [romaan] / tõlkinud Kadre Vaik, Tiina Ristimets. [Tallinn] : Philos, 2002 ; Lescuyer, Jean ; Benchelah, Mehdi. Palverännak Jeruusalemma / prantsuse keelest tõlkinud Jaanus Õunpuu. Tallinn : Olion, 2001 ; Kureishi, Hanif. Lähedus : [romaan] / tõlkinud Aet Varik. [Tallinn] : Huma, 2002

  12. IFLA 39. aastakongress Baltimaades / Peep Moorast

    Index Scriptorium Estoniae

    Moorast, Peep

    2002-01-01

    Rahvusvaheline maastikuarhitektide föderatsiooni IFLA 39. kongress deviisiga "Muutused maastikus" Baltimaades 7.-13. X 2002. Kongressi peakorterist Riias korraldati väljasõite Lätisse, Eestisse ja Leetu. Eesti Põllumajandusülikoolis sümpoosionil esinesid Eestist Tiina Tammet ja Peeter Vassiljev. Eestile esitati kutse astuda IFLA liikmeks

  13. Cannes tõi peo Rumeenia õuele / Merit Kask

    Index Scriptorium Estoniae

    Kask, Merit

    2007-01-01

    Cannes'i filmifestivalil jagati auhindu.Kuldse Palmioksa sai rumeenlase Christian Mungiu "4 kuud, 3 nädalat ja 2 päeva". Ka programmi "Vaatenurk" peaauhinna sai rumeenlane Christian Nemescu ("California Dreamin'"). Lisatud auhinnatute nimekiri, peagi Eesti kinolevisse jõudvate Cannes'i filmide nimekiri ning Tiina Loki kommentaar

  14. Lugu, mis ütles / Kairi Prints

    Index Scriptorium Estoniae

    Prints, Kairi, 1977-

    2011-01-01

    Tantsuteatri Fine 5 tantsulavastusest "Enne kui minna, ma ütlen". Esietendus 24. detsembril Tallinnas lai tänav 9. Fine 5 Laia tänava stuudiost lahkumise spetsiaalse lavastuse lõid Fine 5 koreograafid ja asutajad Tiina Ollesk ja Rene Nõmmik, lavastuses osalevad nad ise koos seitsme tantsijaga

  15. Eesti palus "Fuck you!" pärast andeks

    Index Scriptorium Estoniae

    2003-01-01

    Eesti vabandas Malta ees president Arnold Rüütli riigivisiidi ajal aset leidnud ropendamise pärast. Presidendi kantselei protokolliülem Andrei Birov ütles välisministeeriumi protokolliosakonna peadirektorile Tiina Nirgile tüli käigus: "Fuck you!". Riigivisiit Malta Vabariiki 1.-3.10.2003

  16. Suur rahvusvaheline välisbalti arhiivide konverents südasuvises Tartus / Mai Raud-Pähn ; fotod Madis Laas

    Index Scriptorium Estoniae

    Raud-Pähn, Mai, 1920-

    2006-01-01

    Ettekannetega esinesid: Tiiu Kravtsev, Riina Reinvelt, Juta Kivimäe, Piret Noorhani, Merike Kiipus, Anu Korb, Anne Valmas, Mihkel Volt, Mare Rand, Inga Kuljus, Enn Mainla, Roland Weiler, Teas Tanner, Tiina Kirss, Jüri Kivimäe, Enda-Mai Michelson-Holland, Andrae, Carl Göran, Katrin Meerits ja Maie Barrow

  17. Eesti kirjandussuve nägu / Barbi Pilvre

    Index Scriptorium Estoniae

    Pilvre, Barbi, 1963-

    2000-01-01

    Raud, Rein. Pisiasjad, mis omavd tähtsust. Tln. : Tuum, 2000; Kender, Kaur. Ebanormaalne. Tln. : Eks, 2000; Õunapuu, Ervin. Väike palveraamat. Tln. : Umara, 2000 ; Hellerma, Kärt. Kassandra. Tln. : Hotger, 2000 ; Park, Eeva. Pääse karussellile. Tln. ; Huma, 2000 ; Tammann, Tiina. Tihe udu Tallinnas. Tln. : Perioodika, 2000

  18. Saare jonniga idealist / Lemmi Kann

    Index Scriptorium Estoniae

    Kann, Lemmi

    2008-01-01

    Maxima OÜ tegevjuhist Margus Pärnast. Lisad: Elulugu; Tasub teada. Kommenteerivad: TOP Auto juhatuse esimees Felor Pärnpuu, Sales-Star ASi juhatuse esimees Tiina Aas, psühhiaater Jüri Ennet ning ASi Mobec müügijuht Kaido Sumberg. Vt. samas: Karmi käega õppejõud Pärn

  19. Kodust kehakinnitust Amanda Puhvetist / Vivika Veski

    Index Scriptorium Estoniae

    Veski, Vivika

    2007-01-01

    Psühhiaater Tiina Keldrimale kuuluvast Amanda Puhvetist Üdruma külas Läänemaal. Endisele kauplusehoonele ehitati juurde torn, mille I korrusel on ehtekunstnik Maarja Jõevee Käsitöökuur. Ruumid sisustati vana mööbli ja vanavaraga. Sisearhitekt Martti Ruus. 6 värv. vaadet

  20. Art Loft Berliini südames / Dagmar Reinolt

    Index Scriptorium Estoniae

    Reinolt, Dagmar

    2015-01-01

    Berliini südames asub Saksa arhitektuuribüroo Eike Beckeri poolt loodud kümnekorruseline mängulise fassaadiga hoone. Eesti sisearhitektid Tiina Kesküla, Kätlin Ölluk ja Katy Seppel on loonud sealsetesse korteritesse hubase interjööri. Artiklis on vaatluse all üks korteritest - galeriikorter

  1. Videvikuvaevused ja kehakaemused / Kairi Prints

    Index Scriptorium Estoniae

    Prints, Kairi, 1977-

    2011-01-01

    Nüüdistanstulavastusest "Penombre" ("Videvik"), lavastaja stsenarist, koreograaf ja esitaja Rosalba Torres Guerrero, video autor, stsenarist ja esitaja Lucas Racasse. Etendused 2. ja 3. augustil NO99 Põhuteatris. Tallinna Ülikooli kaasaegse tantsu dotsent ja tantsuteatri Fine5 koreograaf Tiina Ollesk selgitab Rosalba Torres Guerrero liikumise tausta ja tähendust

  2. Millal laps tööle panna? / Kristiina Illak

    Index Scriptorium Estoniae

    Illak, Kristiina

    2007-01-01

    Mõni hakkab raha teenima õige varakult, teine ajab tööl käimata ülikooli lõpuni läbi. Kumb tee on õigem? Lapse töötamise ja kooli kõrvalt töötamise üle arutlevad Katrin Peitre, Toomas Kibus, Lynn Veski ja Tiina Laanem

  3. Lavater ja Goethe / Linnar Priimägi

    Index Scriptorium Estoniae

    Priimägi, Linnar, 1954-

    2016-01-01

    Arvustus: Lavateri näoraamat : valgustusajastu pilk inimesele ja kunstile : toetudes Johann Caspar Lavateri menuteosele "Füsiognoomilisi fragmente inimesetundmise ja ligimesearmastuse edendamiseks" (1775-1778) / koostanud, kommenteerinud ja toimetanud Anu Allikvee ja Tiina-Mall Kreem ; fragmentide tõlge: Katrin Kaugver. Tallinn : Eesti Kunstimuuseum, Mikkeli Muuseum ; Tallinna Ülikool, Akadeemiline Raamatukogu. 2015

  4. Supporting wellbeing in motor neurone disease for patients, carers, social networks, and health professionals: A scoping review and synthesis.

    Science.gov (United States)

    Harris, Melanie; Thomas, Geoff; Thomas, Mary; Cafarella, Paul; Stocks, Allegra; Greig, Julia; McEvoy, R Doug

    2018-04-01

    ABSTRACTObjective:Disease management in motor neurone disease (MND) is focused on preserving quality of life. However, the emphasis has so far been on physical symptoms and functioning and not psychosocial wellbeing. MND affects the wellbeing of carers, of family and social network members, and of healthcare providers, as well as of the patients. We therefore aimed to assess and synthesize the knowledge about maximizing MND-related psychosocial wellbeing across all these groups. We used a systematic search and selection process to assess the scope of the literature along with a narrative synthesis of recent high-quality reviews. The original studies were mainly observational studies of patients and, to a lesser extent, of carers. There were few interventional studies, mainly of patients. There were very few studies of any type on wellbeing in their wider social network or in healthcare professionals. All the review literature looked at MND patient or carer wellbeing, with some covering both. No reviews were found of wellbeing in other family members, patients' social networks, or their healthcare professionals. The reviews demonstrated wellbeing problems for patients linked to psychosocial issues. Carer wellbeing is also compromised. Psychotherapies, social supports, improved decision supports, and changes to healthcare delivery are among the suggested strategies for improved patient and carer wellbeing, but no proven interventions were identified for either. Early access to palliative care, also not well-tested but recommended, is poorly implemented. Work on interventions to deal with well-established wellbeing problems for patients and carers is now a research priority. Explicit use of current methods for patient and public involvement and for design and testing of interventions provide a toolkit for this research. Observational research is needed in other groups. There is a potential in considering needs across patients' social networks rather than looking

  5. Identifying who will benefit from non-invasive ventilation in amyotrophic lateral sclerosis/motor neurone disease in a clinical cohort.

    Science.gov (United States)

    Berlowitz, David J; Howard, Mark E; Fiore, Julio F; Vander Hoorn, Stephen; O'Donoghue, Fergal J; Westlake, Justine; Smith, Anna; Beer, Fiona; Mathers, Susan; Talman, Paul

    2016-03-01

    Respiratory failure is associated with significant morbidity and is the predominant cause of death in motor neurone disease/amyotrophic lateral sclerosis (MND/ALS). This study aimed to determine the effect of non-invasive ventilatory (NIV) support on survival and pulmonary function decline across MND/ALS phenotypes. Cohort recruited via a specialist, multidisciplinary clinic. Patients were categorised into four clinical phenotypes (ALS, flail arm, flail leg and primary lateral sclerosis) according to site of presenting symptom and the pattern of upper versus lower motor neurone involvement. NIV was initiated according to current consensus practice guidelines. Between 1991 and 2011, 1198 patients diagnosed with ALS/MND were registered. 929 patients (77.5%) fulfilled the selection criteria and their data were analysed. Median tracheostomy free survival from symptom onset was 28 months in NIV-treated patients compared to 15 months in untreated (Univariate Cox regression HR=0.61 (0.51 to 0.73), pNIV persisted when the model was adjusted for age, gender, riluzole and percutaneous endoscopic gastrostomy use (HR=0.72 (0.60 to 0.88, p=0.001). In contrast with the only randomised controlled trial, NIV statistically significantly increased survival by 19 months in those with ALS-bulbar onset (Univariate HR=0.50 (0.36 to 0.70), multivariate HR=0.59 (0.41 to 0.83)). These data confirm that NIV improves survival in MND/ALS. The overall magnitude of benefit is 13 months and was largest in those with ALS-bulbar disease. Future research should explore the optimal timing of NIV initiation within phenotypes in order to optimise respiratory function, quality of life and survival. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  6. EMG analysis in 78 cases with motor neuron disease

    Institute of Scientific and Technical Information of China (English)

    Zhang Qiubin

    2000-01-01

    This paper analysed the FMGs of 78 cases with the motor neuron disease(MND). The EMG of all patients showed following characteristics that the average duration of wave prolonged, the average voltage increased and it was found that fibrillation and fasciculatton potentials appeared spontaneously. The fibrillation potential of ENG waa related to course of disease. In the patients whose course of disease was short, the fibri llation potential increased obviously, while in the cases of chronic MND, It usually decreased. The motor nerve conduction velocity of most pa tients (41%) reduced, however, the sensory nerve conduction velocity was normal but two. We reviewed some references about EMG of the motor neuron disease and discussed their characteristics and mechanism

  7. Marilyn Monroe eluloost keisri hullu kannatusteni / Gert Kiiler

    Index Scriptorium Estoniae

    Kiiler, Gert

    2006-01-01

    Ugala uut hooaega tutvustavad lavastajad. Jaak Allik ja Peeter Tammearu lavastavad Jaan Krossi romaani "Keisri hull" järgi samanimelise näidendi, Priit Võigemast Igor Bauersma "norway.today", Kristi Teemusk omakirjutatu järgi lastelavastuse "Kes päästab koletise?" ja Kalju Komissarov Eppu Nuotio, Tiina Brännare muusikali "Marilyn"

  8. Ajalugu ja ajaloo peegeldused / Harry Liivrand

    Index Scriptorium Estoniae

    Liivrand, Harry, 1961-

    2005-01-01

    Tiina Tammetalu ja Lilian Mosolaineni ühisnäitus Hobusepea galeriis, Leonhard Lapini näitus "Looming aastatest 1971-1973" Eesti Panga kuppelsaalis, Liina Siibi näitus "Marlowe" Tallinna Linnagaleriis, Ly Lestbergi näitus "Kusagil mujal" Jaani seegi muuseumis, näitus "Ernö Koch. Ungari kunstnik Eestis" Ungari Instituudi galeriis

  9. Sõprusest ja armastusest / Kristi Paap

    Index Scriptorium Estoniae

    Paap, Kristi

    2011-01-01

    Eesti, läti ja leedu keraamikanäitus "Družba narodov ehk rahvaste sõprus" Eesti Tarbekunsti- ja Disainimuuseumis 10. aprillini 2011. 15 osalejat loetletud. Domilė Ragauskaitė (Leedu), Tõnis Kriisa, Ingrid Alliku ja Tiina Kaljuste töödest. Leo Rohlini fragmentaarium " Nokturn" Tallinnas galeriis Hop 22. veebr. 2011

  10. Ekspert kritiseerib riigiasutuste tööd / Risto Berendson

    Index Scriptorium Estoniae

    Berendson, Risto, 1975-

    2009-01-01

    Tallinna Tehnikaülikooli avaliku halduse instituudi õppetooli juhataja Tiina Randma Liivi eksperthinnangust selgus, et riigiametite töö ei ole täisväärtuslik, kuna ei tehta koostööd teiste asutustega ning ametnikud kardavad oma otsustes võtta vastutust. Arvamus ka Aivar Sõerdilt. Lisa: Väljavõtteid eksperthinnangust

  11. Vana mõisahoone ärkas elule / Heli Salong

    Index Scriptorium Estoniae

    Salong, Heli, 1958-

    2008-01-01

    Muhus asuva Pädaste mõisa peahoone avamist tähistati kultuuriprogrammiga. Kohal viibisid ka president Toomas Hendrik Ilves ja proua Evelin Ilves. Juuresoleval fotol Muhu kooliõpetaja Tiina Saar, mõisaomanikud Martin Breuer ja Imre Sooäär ning proua Evelin Ilves härrastemaja linti läbi lõikamas

  12. Reisipakkumine - Grand Tour Itaalias / Mai Levin

    Index Scriptorium Estoniae

    Levin, Mai, 1942-

    2009-01-01

    Tiina Abeli koostatud ja Urmas Viigi kujundatud näitus "Grand Tour. Eesti kunstnikud Itaalias" Kumu Kunstimuuseumis 05. aprillini. Loetletud eksponeeritud tööde autoreid. Näitus annab ülevaate, kes siinsetest kunstnikest 19. sajandi algusest kuni 1930ndate aastateni Itaalias käisid ja kuidas see nende loomingut mõjutas

  13. Big and small women facing small culture / Reet Varblane

    Index Scriptorium Estoniae

    Varblane, Reet, 1952-

    1999-01-01

    Feministlik kunst Eestis alates 1994. aastast. Näitustest EST. FEM, Kood-eks, Private Views. Videod. Fotoinstallatsioonid. Tuntumad kunstnikud: Mare Tralla, Ene-Liis Semper, Mari Laanemets, Eve Kiiler, Tiina Tammetalu, Kai Kaljo, Ly Lestberg, Liina Siib jt. Kunstnike rühmitused: F.F.F.F. Teemad: ema, väike naine, keha. 6 illustratsiooni

  14. Differential regional cerebral glucose metabolism in clinical syndromes of frontotemporal lobar degeneration: a study with FDG PET

    International Nuclear Information System (INIS)

    Park, J. M.; Cho, S. S.; Na, D. L.; Lee, K. H.; Choi, Y.; Choe, Y. S.; Kim, B. T.; Kim, S. E.

    2001-01-01

    Frontotemporal lobar degeneration( FTLD) is the third most common dementia, following Alzheimer's disease and Lewy body disease. Four prototypic neurobehavioral syndromes can be produced by FTLD: frontotemporal dementia (FTD), frontotemporal dementia with motor neuron disease (MND), semantic dementia (SD), and progressive aphasia (PA). We investigated patterns of metabolic impairment in patient with FTLD presented with four different clinical syndromes. We analysed glucose metabolic patterns on FDG PET images obtained from 34 patients with a clinical diagnosis of FTLD (19 FTD, 6 MND, 6 SD, and 3 PA, according to a consensus criteria for clinical syndromes associated with FTLD) and 7 age-matched healthy controls using SPM99. Patients with FTD had metabolic deficit in the left frontal cortex and bilateral anterior temporal cortex. Hypometabolism in the bilateral premotor are was shown in patients with MND. Patients with SD had metabolic deficit in the left posterior temporal cortex including Wernicke's area, while hypometabolism in the bilateral inferior frontal gyrus including Broca's area and left angular gyrus was seen in patients with PA. These metabolic patterns were well correlated with clinical features of FTLD syndromes. These data provide a biochemical basis of clinical classification of FTLD. FDG PET may help evaluate and classify patients with FTLD

  15. Regional cerebral glucose metabolism in frontotemporal lobar degeneration

    International Nuclear Information System (INIS)

    Park, J.M.; Cho, S.S.; Lee, K.-H.; Choi, Y.; Choe, Y.S.; Kim, B.-T.; Kim, S.E.; Kwon, J.C.; Na, D.L.

    2002-01-01

    Purpose: Frontotemporal lobar degeneration (FTLD) is the third most common cause of dementia, following Alzheimer's disease and Lewy body disease. Four prototypic neuro behavioral syndromes can be produced by FTLD: frontotemporal dementia (FTD), frontotemporal dementia with motor neuron disease (MND), semantic dementia (SD), and progressive aphasia (PA). We investigated patterns of metabolic impairment in patients with FTLD presented with four different clinical syndromes. Methods: We analyzed glucose metabolic patterns on FDG PET images obtained from 34 patients with a clinical diagnosis of FTLD (19 FTD, 6 MND, 6 SD, and 3 PA, according to a consensus criteria for clinical syndromes associated with FTLD) and 7 age-matched healthy controls using SPM99. Results: Patients with FTD had metabolic deficit in the left frontal cortex and bilateral anterior temporal cortex. Hypometabolism in the bilateral pre-motor area was shown in patients with MND. Patients with SD had metabolic deficit in the left posterior temporal cortex including Wernicke's area, while hypometabolism in the bilateral inferior frontal gyrus including Broca's area and left angular gyrus was seen in patients with PA. These metabolic patterns were well correlated with clinical and neuropsychological features of FTLD syndromes. Conclusion: These data provide a biochemical basis of clinical classification of FTLD. FDG PET may help evaluate and classify patients with FTLD

  16. Differential regional cerebral glucose metabolism in clinical syndromes of frontotemporal lobar degeneration: a study with FDG PET

    Energy Technology Data Exchange (ETDEWEB)

    Park, J. M.; Cho, S. S.; Na, D. L.; Lee, K. H.; Choi, Y.; Choe, Y. S.; Kim, B. T.; Kim, S. E. [College of Medicine, Sungkyunkwan Univ., Seoul (Korea, Republic of)

    2001-07-01

    Frontotemporal lobar degeneration( FTLD) is the third most common dementia, following Alzheimer's disease and Lewy body disease. Four prototypic neurobehavioral syndromes can be produced by FTLD: frontotemporal dementia (FTD), frontotemporal dementia with motor neuron disease (MND), semantic dementia (SD), and progressive aphasia (PA). We investigated patterns of metabolic impairment in patient with FTLD presented with four different clinical syndromes. We analysed glucose metabolic patterns on FDG PET images obtained from 34 patients with a clinical diagnosis of FTLD (19 FTD, 6 MND, 6 SD, and 3 PA, according to a consensus criteria for clinical syndromes associated with FTLD) and 7 age-matched healthy controls using SPM99. Patients with FTD had metabolic deficit in the left frontal cortex and bilateral anterior temporal cortex. Hypometabolism in the bilateral premotor are was shown in patients with MND. Patients with SD had metabolic deficit in the left posterior temporal cortex including Wernicke's area, while hypometabolism in the bilateral inferior frontal gyrus including Broca's area and left angular gyrus was seen in patients with PA. These metabolic patterns were well correlated with clinical features of FTLD syndromes. These data provide a biochemical basis of clinical classification of FTLD. FDG PET may help evaluate and classify patients with FTLD.

  17. Aasta parimad interjöörid / Mart Kalm

    Index Scriptorium Estoniae

    Kalm, Mart, 1961-

    2005-01-01

    Eesti Sisearhitektide Liidu aastapreemiad 2004. Võidutööd: Tartu Mänguasjamuuseum (Tea Tammelaan, Krista Lepland, Malle Jürgenson, OÜ Laika, Belka & Strelka); Emil Urbeli projekteeritud kastvilla Miidurannas (Argo Vaikla, Katrin Vaikla, Tiina Teng); Georg Ots Spa hotell Kuressaares (Liisi Murula, Raili Paling). Esemepreemia pälvis Toivo Raidmetsa tool "John", tegevuspreemia sai Maile Grünberg

  18. DVD-d / Andres Laasik

    Index Scriptorium Estoniae

    Laasik, Andres, 1960-2016

    2007-01-01

    Kolm mängufilmide DVD-d : ameerika mängufilm "Kahe tule vahel" ("Departed"; režissöör Martin Scorsese; 2006), inglise mängufilm "Hea aasta" ("A Good Year"; režissöör Ridley Scott; 2006) ja eesti kokandusfilm "10 erinevat liharooga", kus toiduvalmistamist juhivad Madis Milling ja Tiina Kimmel (2007)

  19. Itaalia kunstipärandinäitus Eestis

    Index Scriptorium Estoniae

    2004-01-01

    21. IV-23. V Eesti Kunstimuuseumi Rüütelkonna hoones näitus "Itaalia majoolika kuldajastud. Meistriteoseid Rooma Riiklikust Antiikkunsti Galeriist". Näitusele esitatud majoolikanõud ja keraamilised plaadid on valminud XIII-XIX sajandil. Kuraator Marisa Zaccagnini, näituse ettevalmistamist EKM-s kureeris Tiina Abel. 8. ja 15. V tutvustab Inge Teder majoolikat, selle dekoori ja koolkondi

  20. Kas sinul on juba pääsukesed kõhus? / Maris Meiessaar

    Index Scriptorium Estoniae

    Meiessaar, Maris

    2007-01-01

    Tallinna Ülikooli reklaami ja imagoloogia eriala tudengid osalesid projektis The Pitch, et leida ideed Eesti toidu ja seda tähistava pääsukese logo reklaamimiseks. Võistluse võitis projekt "Kõhu tunne", autoriteks Birgit Jõgeva, Mariliis Lill, Liina Karo, Helen Kask ja Markko Toppi. Võistlust kommenteerib TLÜ reklaami ja meedia osakonna juhataja Tiina Hiob

  1. Modernismi ja rahvusluse vahel / Juta Kivimäe

    Index Scriptorium Estoniae

    Kivimäe, Juta, 1952-

    1998-01-01

    Kolme Balti riigi maailmasõdadevahelist kunstiajalugu käsitlev konverents "Modernity and Identity : Art 1918-1939" 22.-23. okt. Kaunases M. K. Chiurlionise kunstimuuseumis. Esinesid Jolita Muleviciute, Pille Väljataga, Eduards Klavinsh, Osvaldas Daugelis, Tiina Abel, Juta Kivimäe, Anne Lõugas, Sergei Fauchereau (möödunudkevadisest suurnäitusest 1930ndate Euroopa kunstist Pariisi Linna Kunstimuuseumis)

  2. Sirbi tegijad läbi aegade

    Index Scriptorium Estoniae

    2004-01-01

    Toimetaja asetäitjad: Katrin Kivimaa, Reet Varblane jt. Kunst, arhitektuur: Alo Hoidre, Boris Lukats, Ressi Kaera, Jaak Olep, Ike Volkov, Mirjam Peil, Tiina Käesel, Katrin Kivimaa, Vappu Vabar, Reet Varblane, Mari Laaniste. Kunstnikud (arvutikujundus): Tõnu Soo, Ann Gornischeff, Gädvi Kuklase, Piia Ruber. Fotograafid: Solomon Rosenfeldt, Endel Köster, Kalju Suur, Arno Saar, Teet Malsroos

  3. Tallinna ülikoolil on 16 uut doktorit

    Index Scriptorium Estoniae

    2007-01-01

    Aasta jooksul on Tallinna Ülikoolis doktorikraadi kaitsnud 16 inimest. Humanitaarteaduste doktoriteks promoveeritakse Inna Adamson, Maris Saagpakk, Anne Lange, Julia Tofantšuk, Janis Ešots ja Grigori Utgof; kasvatusteaduste doktoriteks Veronika Nagel, Eve Eisenschmidt, Tuuli Oder, Kristina Nugin, Inga Mutso, Tiina Selke ja Boriss Bazanov; loodusteaduste doktoriks Tiit Maran; ning sotsiaalteaduste doktoriteks Signe Dobelniece ja Marge Unt

  4. Safe and Effective Gene Therapy for Murine Wiskott-Aldrich Syndrome Using an Insulated Lentiviral Vector

    Directory of Open Access Journals (Sweden)

    Swati Singh

    2017-03-01

    Full Text Available Wiskott-Aldrich syndrome (WAS is a life-threatening immunodeficiency caused by mutations within the WAS gene. Viral gene therapy to restore WAS protein (WASp expression in hematopoietic cells of patients with WAS has the potential to improve outcomes relative to the current standard of care, allogeneic bone marrow transplantation. However, the development of viral vectors that are both safe and effective has been problematic. While use of viral transcriptional promoters may increase the risk of insertional mutagenesis, cellular promoters may not achieve WASp expression levels necessary for optimal therapeutic effect. Here we evaluate a self-inactivating (SIN lentiviral vector combining a chromatin insulator upstream of a viral MND (MPSV LTR, NCR deleted, dl587 PBS promoter driving WASp expression. Used as a gene therapeutic in Was−/− mice, this vector resulted in stable WASp+ cells in all hematopoietic lineages and rescue of T and B cell defects with a low number of viral integrations per cell, without evidence of insertional mutagenesis in serial bone marrow transplants. In a gene transfer experiment in non-human primates, the insulated MND promoter (driving GFP expression demonstrated long-term polyclonal engraftment of GFP+ cells. These observations demonstrate that the insulated MND promoter safely and efficiently reconstitutes clinically effective WASp expression and should be considered for future WAS therapy.

  5. Lapsepõlve igavesed armid / Aita Kivi

    Index Scriptorium Estoniae

    Kivi, Aita, 1954-

    2001-01-01

    Sisu : Tiia Kriisa. Võõras; Tove Ditlevsen. Lapsepõlve tänav; Tiina Tamman. Õie teekond; Elizabeth Kim. Kümme tuhat muret; Charles Bukowski. Postkontor; Charles Bukowski. Naised; Aarne Ruben. Volta annab kaeblikku vilet; Robyn Sisman. Lihtsalt sõbrad; Charlotte Bingham. Tähetolm; Spencer Johnson. Kes näppas minu juustu?; Jean Webster. Kallis vaenlane; Christoph Gann. Raoul Wallenberg

  6. Elav klassika - happy

    Index Scriptorium Estoniae

    2002-01-01

    14. VI esitleb Imaginaarne Muuseum Haapsalu linnagaleriis Rühm T & Guest Starsi teoseid eelmisest sajandist ja tänapäevast. Tiina Tammetalu koostatud ja kureeritud näitusel osalevad Vilen Künnapu, Raoul Kurtvitz, Lilian Mosolainen, Urmas Muru, Peeter Pere, T. Tammetalu, August Künnapu & Mihkel Mutt, kes esitleb interdistsiplinaarset teost "Kriitik Horriman" ja üliõpilasromaani "Elu allikad"

  7. Baltimaade klaasikunstil on arenguruumi, vajaka jääb võimalustest / Mare Saare

    Index Scriptorium Estoniae

    Saare, Mare, 1955-

    2008-01-01

    Rahvusvaheline klaasinäitus "Vitrum Balticum IV" ("Balti klaas IV") Kaunases kuni 7. XII. Esindatud on Eesti (Kai Kiudsoo-Värv, Eeva Käsper, Ivo Lill, Kairi Orgusaar, Mare Saare, Maret Sarapu, Tiina Sarapu), Läti, Leedu ja Soome klaasikunstnikud. 14. XI rahvusvaheline seminar Läänemeremaade klaasikunsti arengukäigust 21. sajandil kunstiakadeemias. Näituse ja seminari kuraator kunstiteadlane Raimonda Kogelyte-Simanatiene

  8. Eesti ajaloolaste ülemaailmne auhind : dr. Artur Puksovi auhind 2003 / Helmut Piirimäe

    Index Scriptorium Estoniae

    Piirimäe, Helmut, 1930-

    2003-01-01

    Laureaadid: Enn Küng (monograafia "Rootsi majanduspoliitika Narva kaubanduse küsimuses 17. sajandi teisel poolel"); Anti Selart (monograafia "Liivimaa ja Vene 13. sajandil. Uurimus poliitilisest ajaloost"); Tiina Kala (raamat "Euroopa kirjakultuur hiliskeskaegsetes õppetekstides. Tallinna dominiiklase David Sliperi taskuraamat"); Juhan Kreem (monograafia "The Town and Its Lord: Reval and the Teutonic Order"); Andres Tvauri (monograafia "Muinas- Tartu Uurimus Tartu muinaslinnuse ja asula asustusajaloost")

  9. Kas õpetajad on teie kaudu tööd otsinud? / Natalija Gansen, Merit Laan, Ilmar Kütt... [jt.

    Index Scriptorium Estoniae

    2010-01-01

    Küsimusele vastavad: Eesti töötukassa Tallinna ja Harjumaa osakonna teenusekonsultant Natalija Gansen, Eesti töötukassa Viljandimaa osakonna juhataja Merit Laan, Viljandi maavalitsuse haridus- ja sotsiaalosakonna juhataja Ilmar Kütt, CV-Online Estonia OÜ värbamisspetsialist Ivika Born, Lääne-Viru maavalitsuse haridus- ja sotsiaalosakonna vanemspetsialist Tiina Halling ja Valga maavalitsuse haridus- ja kultuuritalituse juhataja Kalle Vister

  10. Teadlased: Pere peaks õpetama eakale digiühiskonnas pensionil olemist / Marju Himma

    Index Scriptorium Estoniae

    Himma, Marju

    2017-01-01

    Iga kahe aasta tagant küsitlevad Tallinna ülikooli rahvastikuteadlased enam kui 6000 üle 50-aastast eesti elanikku. SHARE nime kandev eakateuuring tunneb praegu käimas olevas küsitluslaines huvi inimese lapsepõlve, töö ja lähisuhete vastu. Selgitusi jagavad TLÜ Eesti demograafia keskuse juhataja Luule Sakkeus ja SHARE uuringu projektijuht Tiina Tambaum

  11. Trichtlinnburg tõi esile asjad, mida turist ei näe / Liina Siib

    Index Scriptorium Estoniae

    Siib, Liina

    2005-01-01

    Ajaloolise linnaruumi säilitamist ja arendamist uuriva Euroopa kultuuriprojekti Trichtlinnburg (TLB) Tallinnas toimunud kunstiprojektidest. Sanja Ivekovici video "(If) I Lived Here", Silja Saarepuu ja Villu Plingi objekt "Plats", Anna-Karin Stjerlofi näidispostkaardid, Jüri Ojaveri projekt "Pääsla", Tiina Tammetalu projekt "Seirajad", Katrin Essensoni ja Helen Becki performance'id, David Bate'i fotosari, TLB jalutuskäigud Tallinnas

  12. Üks uks Eesti ja Jaapani vahel : köitekunst kohtub animatsiooniga / Maarja Undusk

    Index Scriptorium Estoniae

    Undusk, Maarja

    2003-01-01

    Eestis viibiv jaapanlanna Maya Yonesho (sünd. 1965) hakkab tegema stipendiaadifilmi "Üks uks". Raamat-uksed teevad valmis eesti nahakunstnikud Külli Grünbach, Rene Haljasmäe, Pille Kivihall, Helen Maran-Poll, Lennart Mänd, Tiina Piisang, Jane Rannamets ja Maarja Undusk. Filmi muusika autor Sven Grünberg. M. Yonesho juhendas nahakunstnik Kadri Halliku diplomitööd

  13. 28. detsembrini on Tallinna keskraamatukogu peahoone näitusesaalis...

    Index Scriptorium Estoniae

    2002-01-01

    Assisi Franciscuse "Päikeselaulule" pühendatud näitus, mis on osa 2002. a. Itaalias Assisis ja Macaretas toimunud II rahvusvahelisest raamatuköitekunsti näituskonkursist, kus Eestist olid 100 medaliga autasustaud kunstniku hulgas Urve Kolde, Kaia Lukats, Esta Voss ja Tiina Piisang, 200 äramärgitud köite autorite seas 18 kunstnikku. Näituse kujundas Tiia Eikholm

  14. Üks raamat mitmes kuues

    Index Scriptorium Estoniae

    2003-01-01

    Kuressaare linnuse kaitsetornis avati Assisi Franciscuse "Päikeselaulule" pühendatud näitus, mis on osa 2002. a. Itaalias Assisis ja Macaretas toimunud II rahvusvahelisest raamatuköitekunsti näituskonkursist, kus Eestist olid 100 medaliga autasustaud kunstniku hulgas Urve Kolde, Kaia Lukats, Esta Voss ja Tiina Piisang, 200 äramärgitud köite autorite seas 18 kunstnikku

  15. Kas olete mõelnud välismaal õpetamisele? / Edward Kess, Helen Oppar, Sergei Ptšjolkin ... [jt.

    Index Scriptorium Estoniae

    2011-01-01

    Küsimusele vastavad Tallinna 37. keskkooli eesti keele ja kirjanduse õpetaja Edward Kess, Varstu keskkooli loodusainete õpetaja Helen Oppar, Tallinna Mustjõe gümnaasiumi füüsikaõpetaja Sergei Ptšjolkin, Sürgavere põhikooli muusikaõpetaja Helve Tähis, Nõo reaalgümnaasiumi inglise keele õpetaja Tiina Tuuling ning Rahumäe põhikooli matemaatikaõpetaja Kadri Hiob

  16. Kuni 13. III saab Y-galeriis vaadata EKA avatud akadeemia näitust "Lavastused ja interpretatsioonid"

    Index Scriptorium Estoniae

    2005-01-01

    Stseenid modellidega on lavastanud Tiina Tammetalu, maalinud-interpreteerinud üliõpilased Ulvi Kuldkepp, Margit Maksing, Liis-Theresia Ulman, (Margus) Soho Fond, Ian Oja, Alissa Didõk-Riikjärv ja Monika Sorokina. Väljapaneku on kujundanud T. Tammetalu ja U. Kuldkepp. Projekt "Happy" on T. Tammetalu kureeritav näitusesari, mis tutvustab tema juhendamisel tehtud üliõpilaste töid

  17. Põhiharidus kolmandal aastatuhandel / Tiina Annus

    Index Scriptorium Estoniae

    Annus, Tiina

    2003-01-01

    Poliitikauuringute Keskuse PRAXIS hariduspoliitika programmi direktor leiab, et kolmanda aastatuhande mõtteviis hariduses tähendab õppija vajaduste ja soovide esiplaanile asetamist ning õpetaja asumist nõustaja ja abistaja rolli. Skeem: Üleminek oskustepõhiselt teadmuspõhisele majandusele. Tabelid. Diagramm: Erinevate vanuserühmade haridustase rahvaloenduse andmeil (31. märts 2000, %-des)

  18. Lähme, naised / Tiina Kuuler

    Index Scriptorium Estoniae

    Kuuler, Tiina, 1969-

    2008-01-01

    Muusikasündmustest: võrokeelse laulu- ja rahvapeo peakontsert "Uma Pido" 31. mail Kubija laululaval, "Türi kevadfest" 30. maist 1. juunini Türil, "Paljassaare RockFest" 31. mail Tallinnas Paljassaare põik 14 sisehoovis, Raplamaa laulu- ja tantsupidu "Mis maa see on" 31. mail ja ansamblite Metsatöll ja Vägilased kontsert 1. juunil Mahtra sõjaväljal, "Vanalinnapäevad" Tallinnas 2.-8. juunil, Lastekaitsepäeva heategevuskontsert 1. juunil Tartus, "Nõmme Kevad" 30. mail Tallinnas Nõmmel Lunastaja kirikus (esinevad Tallinna Muusikakeskkooli kammerkoor ja solistid), Bob Dylan 4. juunil Saku Suurhallis, Punklaulupeo warmup 30. mail Rock Cafes, rocklaulja Sebastian Bach 6. juunil Pirita kloostris

  19. Lähme, naised / Tiina Kuuler

    Index Scriptorium Estoniae

    Kuuler, Tiina, 1969-

    2008-01-01

    Muusikasündmustest: Koit Toome laulab Jaak Joala lauldud laule 25. juulist 31. juulini Eesti kirikutes, "Smilers ETV Live" (kaastegev Üle-Eestilise Noorte Sümfooniaorkestri oktett) 25. juulil Elva laululaval, 27. juulil Keila laululaval ja 31. juulil Pärnu kõlakojas, rahvalauliku Virve Kösteri suvetuur "Mere pidu!" 30. juulil Sõru rannas, 31. juulil Haapsalu piiskopilinnuses, 1. aug. Pärnu vallikäärus ja 2. aug. Tartu Antoniuse õuel, kontsert "Muusa puudutus" 1. aug. Pärnus Ammende villas, festival "Viljandi Folk" 25.-27. juulini, "Airport Jam" 1. ja 2. aug. Kiltsi lennuväljal, "Klaaspärlimäng" Tartu Jaani kirikus 26. juulil, Mustpeade majas Tallinnas 27. juulil, "James Bondi gala" 1. aug. Põltsamaa lossi hoovis, "Ooper Tallinna raekojas" 25. juulil, Saaremaa ooperipäevad 25. juulil Kuressaare lossi ooperimajas, "Hoffmani lood" 26. juulil Kuressaare lossi ooperimajas, "Hullumisstseene kvaliteetooperitest" 27. juulil ja 3. aug. Pärnu vanalinna õues

  20. Lähme, naised / Tiina Kuuler

    Index Scriptorium Estoniae

    Kuuler, Tiina, 1969-

    2008-01-01

    Muusikasündmustest: Rebecca "Inglite pisarad" 10. apr. Tallinnas Toompeal Nelipühi kirikus, "Puhkpilliorkester Tartu 60" 6. apr. Vanemuise kontserdimajas, Singer-Vinger 4. apr. Tallinnas Rock Cafés, "Kolumbus Kris 21" 11. apr. Rock Cafés, "Rock & Roll City" 5. apr. Rock Cafés, Voiceboys 4. apr. Vanemuise kontserdimajas, 5. apr. Jõhvi kontserdimajas ja 6. apr. Estonia kontserdisaalis, "The Musigue Bazaar" 4. apr. Tartus baaris Tige Tikker, Clubarena sünnipäev 4. apr. Tallinnas Mustpeade majas (vt. www.clubarena.com)

  1. Lähme, naised / Tiina Kuuler

    Index Scriptorium Estoniae

    Kuuler, Tiina, 1969-

    2008-01-01

    Muusikasündmustest: Jääboileri kontsert 22. veebr. Tartus Genialistide klubis, "EV 90: Palju õnne, Eesti!" (esinevad Kuressaare lauljad ja rahvatantsijad, tantsuks ansambel Anna Minna) 23. veebr. Kuressaare kultuurikeskuses, Metsatöllu sünnipäev 23. veebr. Tallinnas klubis Woodstock, Etnosari: Vägilased 27. veebr. Estonia Talveaias, Zemfira 23. veebr. Eesti Näituste messikeskuses, Winterfest 22. veebr. Tallinnas Kultuurikatlas, Marju Länik 27. veebr. Türi kultuurimajas, Chris Rea 23. veebr. Tallinnas Saku Suurhallis

  2. Arhitektuurivõistlused 2001 / Tiina Tammet

    Index Scriptorium Estoniae

    Tammet, Tiina, 1971-

    2001-01-01

    Samas "Europan 6" (I preemia Tallinnas: H. Götz, S. Lippardt, M. Jensch ja Tartus: J. Vuorinen, E. Kangas; II preemia Viinis: S. Vallner, O. Kadarik, K. Koov, R. Valner), Narva keskosa planeeringu (I - I. Raukas, T. Tammis, T. Teedumäe), Pärnu vanalinna põhikooli juurdeehituse (II - O. Kadarik, M. Tüür), Pärnu Kontserdimaja (I - H. Grossschmidt, K. Koov, K. Nõmm), Tallinna 21. keskkooli renoveerimise (I - R. Järg, T. Korb), Eesti lähimineviku okupatsioonide muuseumi (I - S. Vallner, I. Peil), Võru Võidu väljaku pargi kujunduse (I-II - P. Müüripeal; V. Tomiste ja V. Valk), nukuteatri sisekujunduse (I - R. Kotov, A. Kõresaar), Eurovisiooni lavakujunduse (I - H. Ermel, A. Nurmela, Ü. Mark) arhitektuurivõistluse tulemused.

  3. 4 talu lilleralli / Tiina Kolk

    Index Scriptorium Estoniae

    Kolk, Tiina, 1956-

    2015-01-01

    Karla külas Harjumaal Kose vallas tegid neli aiandustalu (Roosoja, Roogoja, Pearnahansu ja Sadevälja) 1. aug. väravad valla ja tutvustasid ringkäikudel huvitavaid taimi. Võõrustajad jagasid näpunäiteid roosi, elulõnga, kukerpuu ja aedhortensia kasvatamiseks

  4. Lähme, naised / Tiina Kuuler

    Index Scriptorium Estoniae

    Kuuler, Tiina, 1969-

    2008-01-01

    Muusikasündmustest: "TRE Supershow" 8. veebr. Tartus A Le Coqi Spordimajas, Tõnis Mägi ja Co 6. veebr. Häädemeeste Miikaeli kirikus, Pille Lille Muusikute Toetusfondi Galakontsert 6. veebr. Estonia kontserdisaalis, muusikal "Lumivalgeke ja 7 pöialpoissi" 3. j 10. veebr. Rahvusooperis Estonia, kontsertetendus "Väike Versailles" 2. veebr. ja 3. märtsil Estonias, "Mustlasvanker" 5. veebr. Estonias, Eesti Vabariigi 90. sünnipäevale pühendatud kontsertõhtust 7. veebr. Kuressaare Kultuurikeskuses, kontserdist "Vivaldi "Aastaajad"" 1. veebr. Pärnu Kontserdimajas ja 2. veebr. Jõhvi Kontserdimajas

  5. Lähme, naised / Tiina Kuuler

    Index Scriptorium Estoniae

    Kuuler, Tiina, 1969-

    2008-01-01

    Muusikasündmustest: "Koolilõpupidu" 23. mail Tallinnas Rock Cafés, Valeri Leontjev 26. mail Tallinna Linnahallis, Malang Cissokho 27. mail Tartus Athena keskuses, idamaine pidu "Bazaar" 24. mail Tallinnas teatris NO99, ansamblid Röövel Ööbik, Honey Power ja Lack of Eoins 23. mail ja muusikafestival "Regiöö 2008" 24. mail Tartus Genialistide klubis, Jäneda aia- ja lillepäevad koos simmanitega (esinevad ansamblid Hellad Velled ja PS Troika), Viljandimaa laulupüha ja tantsupidu 24. mail, rahvakultuuripidu Kirde Killad 31. maist 1. juunini Mäetaguse mõisas

  6. Lugemiseks mõeldud / Tiina Tammer

    Index Scriptorium Estoniae

    Tammer, Tiina, 1960-

    2005-01-01

    Tutvustus: Käo, Henno. Väike rüütel Rikardo ; Raud, Piret. Ernesto küülikud ; Kass, Kristiina. Kasper ja viis tarka kassi ; Vaiksoo, Jaanus. Lumemöll ; Made, Reet. Veli Oliver (Tallinn : Tänapäev) - 2004. a. lastejutuvõistluse "Minu esimene raamat" auhinnatud tööd. Neljapäeval, 3. märtsil esitletakse kolme viimast Eesti Lastekirjanduse Teabekeskuses. Vt. ka sõnum: Postimees, 1. märts, lk. 14

  7. Lähme, naised / Tiina Kuuler

    Index Scriptorium Estoniae

    Kuuler, Tiina, 1969-

    2008-01-01

    Muusikasündmustest: Volbriöö peod 30. apr. Tallinnas, Tõrvas, Tartus ja Rakveres, ansambli Köök, ETV tütarlastekoori ja G. Otsa nim. Tallinna Muusikakooli bigbändi kontsert 29. apr. Viljandis Pärimusmuusika Aidas, löökpillimuusika 25. apr. Viljandis Pärimusmuusika Aidas, ürituses "Cabaret Derrida" 25. apr. Tallinnas Kultuurikatlas ja 30. apr. Tartus Sadamateatris, Anne Veski soolokontsert 1. mail Tallinna Linnahallis, kontsert "Anarhy in the Est 2008" 1. mail Tartus, Tshellokvartett C-JAM 26. apr. Vihterpalu mõisas, öölaulupidu 28. apr. Tartu kevadpäevade raames Kassitoome nõlvadel, No Smoking Orchestra 26. apr. Tallinnas Club Von Überblingenis, löökpillimängijate showgrupp Trash.dk 25. apr. Pärnu kontserdimajas ja 26. apr. Vanemuise kontserdimajas

  8. Two Close Ones / Tiina Sarapu

    Index Scriptorium Estoniae

    Sarapu, Tiina

    2006-01-01

    Tallinna IV tarbekunstitriennaalist "Kaks lähedast" Eesti Tarbekunsti- ja Disainimuuseumis 18.03-21.05.2006. Esimese preemia said Kersti Laanmaa ja Tiit Rammul rühmitusest MUKI, teise preemia Caro Bärtling ja Piret Valk. Aukülaliseks inglise ehtekunstnik Wendy Ramshaw oma ehtesarjaga "Picasso's Ladies". Näituse kujundas 3+1 Arhitektid

  9. Katherine Brooke'ist / Tiina Lepiste

    Index Scriptorium Estoniae

    Lepiste, Tiina

    2007-01-01

    Ameerika teleseriaali "Vaprad ja ilusad" ("The Bold and the Beautiful") osatäitja Katherine Kelly Lang (Brooke). Artikli aluseks on Soap Opera Weekly ajakirjaniku Linda Susmani vestlus näitlejannaga

  10. Lähme, naised / Tiina Kuuler

    Index Scriptorium Estoniae

    Kuuler, Tiina, 1969-

    2008-01-01

    Muusikasündmustest: "Peipsimaa kultuuripäevad" 1.-2. aug. Mustvee kultuurikeskuses, Mõisaküla kodukandipäevad" 1.-2. aug. Mõisakülas, "Kapa festival" 2. ja 3. aug. Kohilas Tohisoo pargis, "Heamuusika 2008" 1.- ja 2. aug. Võrtsjärve kaldal Ulgel, "Pillipiknik" 2. aug. Põlvamaal Süvahavval Kalmatemäel, "Marko Matvere merelaulud" 2. aug. Tartus Lodjakojas, Leigo Järvemuusika festival 2. augustil, Katalaani rahvusfestival 2. ja 3. aug. Tallinnas Raekoja platsil, "Viru Folk"8.-10. aug. Käsmus

  11. Apteekrite aed Londonis / Tiina Tammet

    Index Scriptorium Estoniae

    Tammet, Tiina, 1971-

    2012-01-01

    Chelsea lillenäituse kõrval eksisteerivast põneva ajaloo ja taimekollektsiooniga Chelsea Physic Garden'ist - ravimtaimeaiast, kus taimetarkusi õppinud aastasadade jooksul nii apteekrid kui ka meditsiinitudengid

  12. Interdistsiplinaarne, rahvusvaheline / Tiina Käesel

    Index Scriptorium Estoniae

    Käesel, Tiina, 1943-

    2011-01-01

    8. Kaunase tekstiilibiennaalist. Lähemalt Laima Oržekauskienė, Jolanta Šmidtienė, Máximo Laura (Peruu) töödest, Leedu projektist "Tagasikeritud ajalugu". Lühidalt Eesti kollektsioonist satelliitnäituste seas. Läti Kunstiakadeemia 90. aastapäevale ja tekstiilikateedri 50. aastapäevale pühendatud vaibakunsti näitusest Riias

  13. Lähme, naised / Tiina Kuuler

    Index Scriptorium Estoniae

    Kuuler, Tiina, 1969-

    2008-01-01

    Muusikasündmustest: "Levimuusikapäevad" 24.-27. apr. Tartus Genialistide klubis Lutsu teatrimajas, "Peda Folk" 22. apr. Tallinnas Kultuurikatlas (Põhja pst 27a), etnosari "Sotto Voce" 23. apr. Estonia Talveaias, kontsert "Sotspop 2008" 26. apr. Tallinna linnahallis, Jüripäeva kontsert 23. apr. Tallinna Jaani kirikus, Bonzo ja Tõun "Soojad laulud" 18. apr. Pirita Vaba Aja Keskuses, The Suni uue plaadi esitlus 19. apr. Tallinnas Rock Cafes

  14. Lähme, naised / Tiina Kuuler

    Index Scriptorium Estoniae

    Kuuler, Tiina, 1969-

    2008-01-01

    Muusikasündmustest: Rahvusooper Estonia koostöös Nukuteatri ning Teatri- ja Muusikamuuseumiga kutsub lapsi kolmepäevastesse laagritesse kahe nädala jooksul ajavahemikus 9.-20. juunini (vt. www. junior.opera.ee), ansambel "Skriimsilm" 16. mail Tallinnas Rock Cafes, Eesti Kontserdi hooaja lõpp-kontserdid (esineb Helsingi Filharmoonia orkester) 16. mail Jõhvi kontserdimajas ja 17. mail Pärnu kontserdimajas, Puccini gala 16. mail Tallinnas Vene teatris, Backstreet Boys 19. mail Tallinnas Saku Suurhallis, "Küünikontsert: Liisi Koikson" 17. mail Kuusalu vallas Kolgaküla küünis, Busta Rhymes 18. mail Tallinnas Club von Überblingenis

  15. Lähme, naised / Tiina Kuuler

    Index Scriptorium Estoniae

    Kuuler, Tiina, 1969-

    2008-01-01

    Muusikasündmustest: "Flamenkofantaasiad" 2. mail Jõhvi kontserdimajas, "Frank Sinatra gala" 6. mail Vanemuise kontserdisaalis, 7. mail Pärnu kontserdimajas ja 9. mail Tallinna Linnahallis, Brides in Bloom 2. mail Tallinnas Rock Cafes, Demis Roussos 6. mail Saku Suurhallis, Vaiko Epilk ja Eliit heliplaadi "3: Kosmoseodüsseia" esitluskontsert 8. mail Rock Cafés, Chalice'i ja Jürmo Eespere trio kontserdist 6. mail Estonia Talveaias, Ultima Thule, Evergreen 86, Groundhog Day rokk-kontserdil 2. mail Tartus Vabaduse puiesteel

  16. Keelatud viljad kunstihoones / Tiina Kolk

    Index Scriptorium Estoniae

    Kolk, Tiina

    2005-01-01

    Näitusest "Maalimine keelatud/No painting" Tallinna Kunstihoones. Rahvusvahelisel näitusel esinevad kunstnikud Itaaliast, Lätist, Rootsist, Saksamaalt, Soomest, Suurbritanniast, Eestist. Kuraator Anders Härm

  17. Lähme, naised / Tiina Kuuler

    Index Scriptorium Estoniae

    Kuuler, Tiina, 1969-

    2008-01-01

    Muusikasündmustest: rockansamblite Sõpruse Puiestee, Dirty Diana ja Shotgun Suicide peost 15. veebr. Rock Cafés, folklooripeost Pärnus Rääma Nooruse majas, klubi Woodstocki 5. sünnipäeva tähistamisest 15. ja 16. veebr., Ultima Thule kontserdist 15. veebr. Tartu Rockiklubis, festivalist "Eesti teater Estonias"16.-23. veebr.Rahvusooperis Estonia, kontsertidest "Küünlavalgel" 19.-21. veebr. Tallinna Matkamajas, prantsuse duo 2G Kevadjazzil 2008 15. veebr. Tartus Athena keskuses, Raadio Elmari juubelipeost 22. veebr. Pärnu kuursaalis, rootsi bändi Soilwork ja Path Of No Return kontserdist 20. veebr. Tallinnas Rock Cafés

  18. 4 maja lugu / Tiina Kolk

    Index Scriptorium Estoniae

    Kolk, Tiina

    2006-01-01

    Keskaegses kaupmeheelamus Lai tänav 23 paikneb Tallinna Linnateater (taastamistööde juht Teddy Böckler). Endisesse raadiotehasesse Punane RET Tallinnas on ehitatud Sampo panga peakontor (arhitektid Jüri Okas ja Marika Lõoke). Tartus Munga tänaval Eesti Panga Tartu majas (arhitektid Arnold Matteus ja Karl Burman, uue ruumiprogrammi kavandajad Uko Künnap ja Aivar Roosaar) asub Eesti Vabariigi Haridusministeerium. Pärnus endises Herman Leopold Ammende eramus (Peterburi arhitektuuribüroo Mieritz & Gerassimov, renoveeris Aivar Roosaar) asub hotell

  19. Lähme, naised / Tiina Kuuler

    Index Scriptorium Estoniae

    Kuuler, Tiina, 1969-

    2008-01-01

    Muusikasündmustest: ansambli Metsatöll heliplaadi "Iivakivi" esitluskontsertidest 7. märtsil Tallinnas klubis Hollywood ja 8. märtsil Tartu Sadamateatris, Ultima Thule sünnipäevakontserdist 7. märtsil Tallinnas Rock Cafés, Jäääär 8. märtsil Rock Cafés, Koit Toome ja Uku Suviste 12. märtsil Pärnu kontserdimajas, Kuninglik kvintett 8. märtsil Kiviõli rahvamajas, "Naerata nüüd jälle sa" (Maarja-Liis Ilus, Alen Veziko, Margus Vaher, Andre Hein, Raimondo Laikre) 9. märtsil Vanemuise kontserdimajas, "Kaunimad... su elus" (ansambel Kaunimate Aastate Vennaskond) 7. märtsil Jõhvi kontserdimajas, 8. märtsil Vanemuise kontserdimajas ja 9. märtsil Pärnu kontserdimajas, Tarmo ja Toomas Urb 8. märtsil Viljandi kultuurimajas, Koit Toome 7. märtsil Tartu Jaani kirikus, Noorkuu naistepäevakontsert 8. märtsil Rakvere spordihallis, Eesti heliloojate armastuslaulud ETV tütarlastekoori esituses 8. märtsil Jõhvi kontserdimajas, Brides in Bloom + DJ Kahurid 8. märtsil Tallinnas klubis Woodstock, Richard Clayderman 11. märtsil Estonia kontserdisaalis

  20. Reinold Korner, linnakirjutaja / Tiina Kala

    Index Scriptorium Estoniae

    Kala, Tiina

    2006-01-01

    Tallinna keskaegsete kirjutajate isikutest. Nende tööst : keskaegsetest linnaraamatutest, märkmeteraamatutest, pärandi- ja rendiseraamatutest, arveraamatutest, kodanikeraamatust ja muudest dokumentidest. Kirjutaja elatisest. Reinold Korner oli Lübeckist pärit vaimulik. Tema tööst Tallinna raekirjutajana. Reinold Korneri varaloendist ja testamendist

  1. Ag/MnO₂ Nanorod as Electrode Material for High-Performance Electrochemical Supercapacitors.

    Science.gov (United States)

    Guo, Zengcai; Guan, Yuming; Dai, Chengxiang; Mu, Jingbo; Che, Hongwei; Wang, Guangshuo; Zhang, Xiaoliang; Zhang, Zhixiao; Zhang, Xiliang

    2018-07-01

    A one-dimensional hierarchical Ag nanoparticle (AgNP)/MnO2 nanorod (MND) nanocomposite was synthesized by combining a simple solvothermal method and a facile reduction approach in situ. Owing to its high electrical conductivity, the resulting AgNP/MND nanocomposite displayed a high specific capacitance of 314 F g-1 at a current density of 2 A g-1, which was much higher than that of pure MNDs (178 F g-1). Resistances of the electrolyte (Rs) and charge transportation (Rct) of the nanocomposite were much lower than that of pure MNDs. Moreover, the nanocomposite exhibited outstanding long-term cycling ability (9% loss of initial capacity after 1000 cycles). These results indicated that the nanocomposite could serve as a promising and useful electrode material for future energy-storage applications.

  2. Minor neurological dysfunction and cognition in 9-year-olds born at term

    NARCIS (Netherlands)

    Kikkert, Hedwig K; de Jong, Corina; Hadders-Algra, Mijna

    BACKGROUND: In children with developmental disorders, motor problems often co-occur with cognitive difficulties. Associations between specific cognitive deficits underlying learning problems and minor neurological dysfunction (MND) are still unknown. AIMS: To assess associations between specific

  3. My NASA Data

    Data.gov (United States)

    National Aeronautics and Space Administration — MY NASA DATA (MND) is a tool that allows anyone to make use of satellite data that was previously unavailable.Through the use of MND’s Live Access Server (LAS) a...

  4. Multimodal structural MRI in the diagnosis of motor neuron diseases.

    Science.gov (United States)

    Ferraro, Pilar M; Agosta, Federica; Riva, Nilo; Copetti, Massimiliano; Spinelli, Edoardo Gioele; Falzone, Yuri; Sorarù, Gianni; Comi, Giancarlo; Chiò, Adriano; Filippi, Massimo

    2017-01-01

    This prospective study developed an MRI-based method for identification of individual motor neuron disease (MND) patients and test its accuracy at the individual patient level in an independent sample compared with mimic disorders. 123 patients with amyotrophic lateral sclerosis (ALS), 44 patients with predominantly upper motor neuron disease (PUMN), 20 patients with ALS-mimic disorders, and 78 healthy controls were studied. The diagnostic accuracy of precentral cortical thickness and diffusion tensor (DT) MRI metrics of corticospinal and motor callosal tracts were assessed in a training cohort and externally proved in a validation cohort using a random forest analysis. In the training set, precentral cortical thickness showed 0.86 and 0.89 accuracy in differentiating ALS and PUMN patients from controls, while DT MRI distinguished the two groups from controls with 0.78 and 0.92 accuracy. In ALS vs controls, the combination of cortical thickness and DT MRI metrics (combined model) improved the classification pattern (0.91 accuracy). In the validation cohort, the best accuracy was reached by DT MRI (0.87 and 0.95 accuracy in ALS and PUMN vs mimic disorders). The combined model distinguished ALS and PUMN patients from mimic syndromes with 0.87 and 0.94 accuracy. A multimodal MRI approach that incorporates motor cortical and white matter alterations yields statistically significant improvement in accuracy over using each modality separately in the individual MND patient classification. DT MRI represents the most powerful tool to distinguish MND from mimic disorders.

  5. Multimodal structural MRI in the diagnosis of motor neuron diseases

    Directory of Open Access Journals (Sweden)

    Pilar M. Ferraro

    2017-01-01

    Full Text Available This prospective study developed an MRI-based method for identification of individual motor neuron disease (MND patients and test its accuracy at the individual patient level in an independent sample compared with mimic disorders. 123 patients with amyotrophic lateral sclerosis (ALS, 44 patients with predominantly upper motor neuron disease (PUMN, 20 patients with ALS-mimic disorders, and 78 healthy controls were studied. The diagnostic accuracy of precentral cortical thickness and diffusion tensor (DT MRI metrics of corticospinal and motor callosal tracts were assessed in a training cohort and externally proved in a validation cohort using a random forest analysis. In the training set, precentral cortical thickness showed 0.86 and 0.89 accuracy in differentiating ALS and PUMN patients from controls, while DT MRI distinguished the two groups from controls with 0.78 and 0.92 accuracy. In ALS vs controls, the combination of cortical thickness and DT MRI metrics (combined model improved the classification pattern (0.91 accuracy. In the validation cohort, the best accuracy was reached by DT MRI (0.87 and 0.95 accuracy in ALS and PUMN vs mimic disorders. The combined model distinguished ALS and PUMN patients from mimic syndromes with 0.87 and 0.94 accuracy. A multimodal MRI approach that incorporates motor cortical and white matter alterations yields statistically significant improvement in accuracy over using each modality separately in the individual MND patient classification. DT MRI represents the most powerful tool to distinguish MND from mimic disorders.

  6. Uus Tants 7 / Mikko Orpana

    Index Scriptorium Estoniae

    Orpana, Mikko

    2005-01-01

    Tallinnas 2005. aasta märtsikuus toimunud tantsufestifalist "Uus tants 7". Pikemalt peatutakse Mart Kangro lavastusel "Out of Functions" ning Oksana Titova ja Taavet Janseni lavastusel "The Last Hairy", aga juttu on ka Renate Valme teosest "Mesta", samuti Tiina Olleski ja Rene Nõmmiku "Body Experience Time", Katrin Essensoni ja Taavi Eelmaa "The Thoughts with Manus" ja Krõõt Juuraku "Artistic Approach 3. I"

  7. Eesti keha kate / Milla Mägi

    Index Scriptorium Estoniae

    Mägi, Milla, 1949-

    2005-01-01

    Konkursist "Eesti keha kate", mille eesmärk oli ärgitada tegema moodsaid rõivaid rahvakunsti ja rahvusliku käsitöötraditsiooni vaimus. I preemia - Liisa Murdvee kangastelgedel kootud kaltsumaterjalist mantel ja jakk, II - Tiina Reeseni rahvuslik komplekt emale ja tütrele, V - Eve Sisa tikandiga korsett, "Kodukolde" auhind - Aide Leit-Lepmetsa Haapsalu pitsi motiividel pruutkleit. 6 värv. ill

  8. Eesti disain / Silvia Pärmann

    Index Scriptorium Estoniae

    Pärmann, Silvia

    2014-01-01

    Ahti Grünbergi ja Tõnis Kalve mööbliseeria Derelict. Maile Grünbergi disainitud toolid ja laud Madis. Taniel Kolpakovi kaubamärgile Rough Bloom disainitud köögimööbel. Kaubamärgi Varm Country uus kollektsioon Basic no 2. Kersti Laanmaa keraamilised teekannud Kiviaeg ja Jänes kapsas. Tiina Mangi kavandatud diivan Sik-Sak. Tõnis Vellama valgustimudel AET27

  9. PÖFF-i alafestivalid lükati käima

    Index Scriptorium Estoniae

    2010-01-01

    14. korda toimuva Pimedate Ööde Filmifestivali tänavune fookus on soome filmidel ja Euroopa filmiauhindade nominentide töödel. PÖFF-i põhiprogrammi tutvustab peakorraldaja Tiina Lokk, tudengi- ja lühifilmide festivali Sleepwalkers kava festivali juht Helen Vinogradov, animafilmide festivali Animated Dreams kava programmijuht Heilika Pikkov, laste- ja noortefilmide festivali Just Film kava festivali juht Mikk Granström

  10. Aasta parimad interjöörid muutsid vana trendikaks / Piret Tali

    Index Scriptorium Estoniae

    Tali, Piret, 1972-

    2001-01-01

    Eesti Sisearhitektide Liidu aastapreemiad: eramu sisekujunduse preemia - Tüüne-Kristin Vaikla ja Urmas Vaikla, meelelahutusliku interjööri preemia - kohvik "Pegasus" (Gert Sarv, Margus Tammik, Tarvo H. Varres osaühisusest Front Arhitektid), ajaloolise interjööri preemia - Tallinna Reaalkooli renoveerimisprojekt Tiina Lõhmuse juhtimisel, unikaaleseme preemia - Leila Pärtelpoja kujundatud riigikogu esimehe puhkeruumi mööbel Toompeal. Nimetatud žürii koosseis

  11. Värvi triumf / Mai Levin

    Index Scriptorium Estoniae

    Levin, Mai, 1942-

    2010-01-01

    Näitus "Neoimpressionismi jälgedes. Mägi ja Finch" Kumu Kunstimuuseumis 12. septembrini 2010. Kuraator Tiina Abel, kuraatori abi Liisa Kaljula, kujundaja Inga Heamägi. Puäntillismi mõjust, Konrad Mäe pöördumisest täppiva laadi poole. Inglise päritolu belgia-soome kunstniku Alfred William Finchi avastamisest. Prantsuse ja eesti kunstnike töödest näitusel

  12. Amyotrophic lateral sclerosis or not: Keys for the diagnosis.

    Science.gov (United States)

    Lenglet, T; Camdessanché, J-P

    2017-05-01

    Amyotrophic lateral sclerosis (ALS) is a degenerative motor neuron disease (MND) which prognosis is poor. Early diagnosis permit to set up immediately adapted treatment and cares. Available diagnostic criteria are based on the detection of both central and peripheral motor neuron injury in bulbar, cervical, thoracic and lumbar regions. Electrodiagnostic (EDX) tests are the key tools to identify peripheral motor neuron involvement. Needle examination records abnormal activities at rest, and looks for neurogenic pattern during muscle contraction. Motor unit potentials morphology is modified primary to recruitment. Motor evoked potentials remain the test of choice to identify impairment of central motor neurons. In the absence of diagnostic biomarker of ALS and among essential investigations of suspected MND, a careful clinical and neurophysiological work-up is essential to rule out the differential diagnosis. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  13. Neurological condition assessed with the Hempel examination and cognition and behaviour at 4 years

    NARCIS (Netherlands)

    Schendelaar, Pamela; Seggers, Jorien; Heineman, Maas Jan; Hadders-Algra, Mijna

    Aim: To investigate associations between neurological condition, assessed with the Hempel examination, in terms of minor neurological dysfunction (MND) and neurological optimality, and cognition and behaviour at 4 years. Study design: Cross-sectional analyses within a prospective, assessor-blinded

  14. Pain in Neurodegenerative Disease : Current Knowledge and Future Perspectives

    NARCIS (Netherlands)

    de Tommaso, Marina; Arendt-Nielsen, Lars; Defrin, Ruth; Kunz, Miriam; Pickering, Gisele; Valeriani, Massimiliano

    2016-01-01

    Neurodegenerative diseases are going to increase as the life expectancy is getting longer. The management of neurodegenerative diseases such as Alzheimer's disease (AD) and other dementias, Parkinson's disease (PD) and PD related disorders, motor neuron diseases (MND), Huntington's disease (HD),

  15. Aerobic exercise and congnitive behavioural therapy in ALS: optimzing quality of life

    NARCIS (Netherlands)

    van der Lans-van Groenestijn, A.C.

    2017-01-01

    Amyotrophic lateral sclerosis (ALS) is a fatal progressive adult-onset neurodegenerative motor neuron disease (MND). In the absence of an effective treatment, ALS care focuses on symptom treatment, optimizing functioning (daily activities and social participation) and maintaining quality of life

  16. Perekond on kolmes kohas / Ave Randviir

    Index Scriptorium Estoniae

    Randviir, Ave, 1981-

    2006-01-01

    Tallinn Pride 2006 kultuurinädala raames Viru keskuses samasooliste paaride suhteid kujutav maalinäitus "Meie oleme perekond". Esinevad Tiina Tammetalu, Lilian Mosolainen ja Pille Neeve. Samanimeline näitus Cafe Angel'is Chintis Lundgreni ja Heikki-Erich Merila töödest ning kinos Sõprus kunstnike ühenduse Infotankistid (Anu Vahtra, Reimo Võsa-Tangsoo, Katrin Tees, Maris Mändel, Taavi Suits, Sulo Kallas, Piret Räni) fotonäitus

  17. Digitaalisen markkinointiviestinnän mahdollisuudet : Case Kelloliike EA Lahti Oy

    OpenAIRE

    Harmaala, Tiina

    2011-01-01

    TIIVISTELMÄ Harmaala, Tiina. 2011. Digitaalisen markkinointiviestinnän mahdollisuudet – Case Kelloliike EA Lahti Oy. Opinnäytetyö. Kemi-Tornion ammattikorkeakoulu. Kaupan ja kulttuurin toimiala. Sivuja 62. Opinnäytetyön tavoitteena on Kelloliike EA Lahti Oy:n digitaalisen markkinointiviestinnän suunnittelu. Tutkimuksessa tarkastelen digitaalista markkinointiviestintää integroidun markkinointiviestinnän näkökulmasta. Tutkimuksen tarkoituksena on selvittää toimeksiantajalle sen markkino...

  18. Põlvkondade triloogia Von Krahli teatris / Hedi-Liis Toome

    Index Scriptorium Estoniae

    Toome, Hedi-Liis

    2010-01-01

    Von Krahli teatri lavastustest: William Shakespeare "Kuningas Lear", mängib Viljandi Kultuuriakadeemia 8. lend, lavastaja Peeter Jalakas (esietendus 30. jaan. 2010); "The End" - autorid, lavastajad ja näitlejad: Mari Abel, Tiina Tauraite, Riina Maidre, Erki Laur, Taavi Eelmaa, Juhan Ulfsak (esietendus 19. märts 2010); "Mehed lumes" Peter Freucheni jutustuse "Olavi lugu" ainetel lavastanud Mart Koldits ja Kristjan Sarv, kes ka ise mängivad (17. aprill 2010)

  19. Inspiratsiooni lätetel Amsterdamis : kuhu püüelda ja millest hoiduda... / Eve Koha

    Index Scriptorium Estoniae

    Koha, Eve

    2002-01-01

    Ülemaailmse klaasikunsti ühingu Glass Art Society 32. aastakonverentsist Amsterdamis 30. V-2. VI. Eestist osalesid Viivi-Ann Keerdo, Eve Koha, Kai Koppel, Eeva Käsper-Lennuk, Ivo Lill ja Tiina Sarapu. Näitusel "Young and Hot, European Emerging Artists" esindasid Eestit E. Käsper-Lennuk ja T. Sarapu. Elutööpreemiad ameeriklasele Fritz Dreisbachile (sünd. 1941) ja taanlasele Finn Lynggaardile (sünd. 1939)

  20. Motor neuron disease: the impact of decreased speech intelligibility ...

    African Journals Online (AJOL)

    Background: The onset of motor neuron disease (MND), a neurodegenerative disease, results in physical and communication disabilities that impinge on an individual's ability to remain functionally independent. Multiple aspects of the marital relationship are affected by the continuously changing roles and responsibilities.

  1. Handwriting, visuomotor integration, and neurological condition at school age

    NARCIS (Netherlands)

    van Hoorn, Jessika F.; Maathuis, Carel G. B.; Peters, Lieke H. J.; Hadders-Algra, Mijna

    2010-01-01

    Aim The study investigated the relationships between handwriting, visuomotor integration, and neurological condition. We paid particular attention to the presence of minor neurological dysfunction (MND). Method Participants were 200 children (131 males, 69 females; age range 8-13y) of whom 118

  2. Test-retest, inter-assessor and intra-assessor reliability of the modified Touwen examination

    NARCIS (Netherlands)

    Peters, Lieke H. J.; Maathuis, Karel G. B.; Kouw, Eva; Hamming, Marjolein; Hadders-Algra, Mijna

    Interest in the Touwen examination (1979) for the assessment of minor neurological dysfunction (MND) is growing. However, information on psychometric properties of this assessment is scarce. Therefore the present study aimed at assessing the test's test-retest, inter- and intra-assessor reliability.

  3. Kutsega raamatukoguhoidjate read täienevad : kokkuvõte kutse taotlemisest 2016. a / Krista Talvi

    Index Scriptorium Estoniae

    Talvi, Krista, 1948-

    2016-01-01

    Raamatukoguhoidja kutsestandardi tase 8 omistati Tiiu Reimole, kes on töötanud raamatukogus ja olnud õppejõud ning töötab praegu Tallinna Ülikooli Akadeemilises Raamatukogus Eesti retrospektiivse rahvusbibliograafia keskuses

  4. Clinical profile of motor neuron disease patients with lower urinary tract symptoms and neurogenic bladder.

    Science.gov (United States)

    Vázquez-Costa, Juan Francisco; Arlandis, Salvador; Hervas, David; Martínez-Cuenca, Esther; Cardona, Fernando; Pérez-Tur, Jordi; Broseta, Enrique; Sevilla, Teresa

    2017-07-15

    Lower urinary tract symptoms (LUTS) are frequent in motor neuron disease (MND) patients, but clinical factors related to them are unknown. We describe differences in LUTS among MND phenotypes and their relationship with other clinical characteristics, including prognosis. For this study, we collected clinical data of a previously published cohort of patients diagnosed with classical amyotrophic lateral sclerosis (cALS), progressive muscular atrophy (PMA) or primary lateral sclerosis (PLS) with and without LUTS. Familial history was recorded and the C9ORF72 expansion was analysed in the entire cohort. Patients were followed-up for survival until August 2016. Fifty-five ALS patients (37 cALS, 10 PMA and 8 PLS) were recruited. Twenty-four reported LUTS and neurogenic bladder (NB) could be demonstrated in nine of them. LUTS were not influenced by age, phenotype, disability, cognitive or behavioural impairment, or disease progression, but female sex appeared to be a protective factor (OR=0.39, p=0.06). Neither family history nor the C9ORF72 expansion was linked to LUTS or NB. In the multivariate analysis, patients reporting LUTS early in the disease course tended to show poorer survival. In this study, LUTS appear to be more frequent in male MND patients, but are not related to age, clinical or genetic characteristics. When reported early, LUTS could be a sign of rapid disease spread and poor prognosis. Further prospective longitudinal and neuroimaging studies are warranted to confirm this hypothesis. Copyright © 2017 Elsevier B.V. All rights reserved.

  5. Studies on motor neuron disease with cranial magnetic resonance imaging

    Energy Technology Data Exchange (ETDEWEB)

    Mitsui, Yoshiyuki; Takahashi, Mitsuo; Nakamura, Yusaku; Kitaguchi, Masataka; Yagi, Yuji (Kinki Univ., Osaka (Japan). School of Medicine)

    1992-05-01

    The present study was performed to examine the pyramidal tracts of the brain in both 51 normal subjects (21 male and 30 female subjects; mean age of 43.5[+-]16.1 years) and 12 patients with motor neuron disease (6 male and 6 female patients; mean age of 57.4[+-]7.9 years), using the magnetic resonance imaging (MRI). The 12 patients with motor neuron disease (MND) comprised 7 suffering from spinal progressive muscular atrophy (SPMA) and 5 from amyotrophic lateral sclerosis (ALS). The MRI used in this study was of both short spin echo and long spin echo sequence. Of the 52 normal subjects, 24 of them (47%) had the T2 prolonged small areas (high signal intensity areas) at the posterior limb of internal capsule. These findings were not found in the normal subjects over fifty years old. No similar finding was detected in the pyramidal tracts except the posterior limb of internal capsule. On the other hand, 8 patients with MND (67%) proved to have the high signal intensity areas in the pyramidal tracts. Moreover, these high intensity areas were extended from the crus cerebri to corona radiata in 7 patients (58%). In all patients with ALS, these areas were extended in whole areas of the pyramidal tracts, and the similar findings were also found in two patients with SPMA. These findings were demonstrated to be more extensive than those in the normal subjects. The results thus obtained warrant us to conclude that cranial MRI is useful to detect the degeneration of the pyramidal tracts of MND patients. (author).

  6. CSF glial markers correlate with survival in amyotrophic lateral sclerosis.

    Science.gov (United States)

    Süssmuth, S D; Sperfeld, A D; Hinz, A; Brettschneider, J; Endruhn, S; Ludolph, A C; Tumani, H

    2010-03-23

    In neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), CSF biomarkers are increasingly studied to evaluate their relevance for differential diagnosis, disease progression, and understanding of pathophysiologic processes. To identify a biomarker profile of neuronal and glial CSF proteins to discriminate ALS from other motor neuron diseases (MND) and to assess whether baseline levels of CSF measures in ALS are associated with the course of the disease. A total of 122 consecutive subjects with MND were included in this cross-sectional study (ALS, n = 75; lower motor neuron syndrome, n = 39; upper motor neuron diseases, n = 8). Clinical follow-up included 76 patients. We determined baseline levels of protein tau and astroglial S100beta in CSF and microglial sCD14 in CSF and serum in relation to diagnosis, duration of disease, and survival. CSF tau was significantly elevated in ALS and upper motor neuron diseases as compared to lower motor neuron diseases and controls. CSF S100beta levels were significantly lower in lower motor neuron diseases as compared to other MND. CSF concentrations of S100beta and sCD14 correlated with the survival time in patients with ALS. In motor neuron diseases, CSF tau elevation indicates the degeneration of upper motor neurons, while S100 beta and sCD14 may indicate the activation of CNS glial cells. Because S100beta and sCD14 concentrations correlate with survival in amyotrophic lateral sclerosis (ALS), we suppose that the combination of both markers may be useful to obtain prognostic information in patients with ALS.

  7. Quality of general movements and the development of minor neurological dysfunction at toddler and school age

    NARCIS (Netherlands)

    Hadders-Algra, M; Mavinkurve-Groothuis, AMC; Stremmelaar, EF; Martijn, A; Butcher, PR; Groen, S.E

    Objective: To evaluate the reliability of assessing infants' general movements (GMs) using a new classification and its validity in predicting complex minor neurological dysfunction (MND) at toddler and at school age. Design: Prospective study of two groups of infants, each consisting of a mix of

  8. TDP-43 in Familial and Sporadic Frontotemporal Lobar Degeneration with Ubiquitin Inclusions

    NARCIS (Netherlands)

    Cairns, Nigel J.; Neumann, Manuela; Bigio, Eileen H.; Holm, Ida E.; Troost, Dirk; Hatanpaa, Kimmo J.; Foong, Chan; White, Charles L.; Schneider, Julie A.; Kretzschmar, Hans A.; Carter, Deborah; Taylor-Reinwald, Lisa; Paulsmeyer, Katherine; Strider, Jeffrey; Gitcho, Michael; Goate, Alison M.; Morris, John C.; Mishrall, Manjari; Kwong, Linda K.; Stieber, Anna; Xu, Yan; Forman, Mark S.; Trojanowski, John Q.; Lee, Virginia M.-Y.; Mackenzie, Ian R. A.

    2007-01-01

    TAR DNA-binding protein 43 (TDP-43) is a major pathological protein of sporadic and familial frontotemporal lobar degeneration with ubiquitin-positive, tau-negative inclusions (FTLD-U) with or without motor neuron disease (MND). Thus, TDP-43 defines a novel class of neurodegenerative diseases called

  9. Eesti proosa 2007 - kultuuri ja tsivilisatsiooni vahel / Peeter Helme

    Index Scriptorium Estoniae

    Helme, Peeter, 1978-

    2010-01-01

    2007. a. ilmunud proosaraamatutest: Tiina Laanemi "Väikesed vanamehed", Ene Mihkelsoni "Katkuhaud", Toomas Vindi "Mäluauguga naine", Vahur Afanasjevi "Kaadrid otsustavad", Armin Kõomäe "Nägu, mis jäi üle" (ilmus 2006. a.), Jaan Kaplinski "Seesama jõgi", Tõnu Õnnepalu "Flandria päevik", Maimu Bergi "Unustatud inimesed", Mehis Heinsaare "Rändaja õnn", Mihkel Muti "Siseemigrant", Aarne Biini "Linna valitsemine", Ivar Silla "Tantsiv linn" ja Epp Annuse "Sina, Matilda"

  10. Villa Miidurannas = Villa in Miiduranna / Triin Ojari

    Index Scriptorium Estoniae

    Ojari, Triin, 1974-

    2004-01-01

    Maja on kolmest küljest suletud kast, lahtine on vaid merepoolne külg, pälvis 2003. a. parima betoonehitise preemia. Projekteerija: AB Emil Urbel. Autor Emil Urbel, kaasa töötas Indrek Erm. Sisekujundus: Katrin ja Argo Vaikla, Tiina Teng (Vaikla Disain). Konstruktor TA Konsult. Projekt 2001, valmis 2004. Üldpind: 528 mø. Ill.: I, II ja III korruse plaan, 3 välis- ja 5 sisevaadet, värv

  11. 18. II avati Jõgeva kultuurikeskuses... / Hele Tallinn

    Index Scriptorium Estoniae

    Tallinn, Hele

    2005-01-01

    Koos Tartu naiskoori Laulikud kontserdiga avati nahaköitekunsti näitus "Assisi Franciscuse "Päikeselaul" ehk "Ülemlaul loojale"", mis on osa 2002. a. Itaalias Assisis ja Macaretas toimunud II rahvusvahelisest raamatuköitekunsti näituskonkursist. Eestist pääses 100 medaliga autasustatud meistri hulka Urve Kolde, Kaia Lukats, Tiina Piisang ja Esta Voss. 200 äramärgitud töö hulgas on 18 eesti autori tööd

  12. Renessanslik vetemäng / Tiina Tammet

    Index Scriptorium Estoniae

    Tammet, Tiina, 1971-

    2009-01-01

    Rooma lähedal Tivoli linnakeses asuvast Itaalia 16. sajandi renessansiaegse palee ja aiakunsti pärlist Villa d'Este, mis on UNESCO maailmapärandi nimekirjas. Pargi ja palee arhitektid Pirro Ligorio ja Alberto Galvani, purskkaevude autoriks skulptor Gianlorenzo Bernini

  13. "Marilyn" korjas õunad endale / Tiina Sarv

    Index Scriptorium Estoniae

    Sarv, Tiina, 1949-

    2007-01-01

    Ugala tiigi ääres jagati 21. juunil Kuldõuna nime kandvaid publikupreemiaid. Kuldõuna laureaadid on "Marilyni" lavastaja Kalju Komissarov, kujundaja Jaak Vaus, nimosatäitja Hilje Murel ning lavastuses "Kolm klaasikest kirsiviina" silma paistnud näitleja Aarne Soro

  14. Naiste poliitilise esindatuse edendamine / Tiina Laur

    Index Scriptorium Estoniae

    Laur, Tiina

    2003-01-01

    EL-i projekti " EL laienemine, sotsiaalne sugu ja valitsemine" (EGG) raames läbiviidud intervjuude baasil tehtud analüüs naiste suhtumisest sookvootidesse, naiste poliitilisse aktiivsusesse ja viimase edendamisse. Tabelid: Valimas käinute sooline osakaal, %; Naiste osakaal kandidaatide ja valituks osutunute seas, 1992-2003

  15. Ilusad, otstarbekad ja nutikad / Tiina Kolk

    Index Scriptorium Estoniae

    Kolk, Tiina

    2011-01-01

    Konkursi "Eesti parimad interjöörid ja disain 2010" võidutööd: ADM Interactive'i bürooruumid (Ühiskondliku interjööri preemia), kohvik Supelsaksad (Söögikoha interjööri preemia), välinäitus "Eesti kirjanik karikatuuris" (Näituse ja installatsiooni kujunduse preemia), Kihnu muuseum (Ajaloolise interjööri preemia). Nimetatud võidutööde autorid ja žürii koosseis. Nominentide töödest on avatud Arhitektuuri- ja Disainigaleriis 31. maini näitus

  16. Noored vabatahtlikud Võrumaa lasteaias / Tiina Vapper

    Index Scriptorium Estoniae

    Vapper, Tiina, 1955-

    2014-01-01

    Võru Punamütsikese lasteaia liitumisest Euroopa Noored programmiga. Sel aastal töötavad lasteaias Charlotte Clatot Prantsusmaalt ja Sushanik Ghazaryan Armeeniast, eelmisel aastal Marcus Paetzold Saksamaalt

  17. Väitekiri Itaalia reisikirjadest / Tiina Kirss

    Index Scriptorium Estoniae

    Kirss, Tiina, 1957-

    2009-01-01

    Arvustus: Kõvamees, Anneli. Itaalia Eesti reisikirjades: Karl Ristikivi "Itaalia capriccio" ja Aimée Beekmani "Plastmassist südamega madonna". Tallinn : Tallinna Ülikooli Kirjastus, 2008. (Tallinna Ülikooli humanitaarteaduste dissertatsioonid ; 21)

  18. Millist perepoliitikat me vajame? / Tiina Veismann

    Index Scriptorium Estoniae

    Veismann,Tiina, 1967-

    2003-01-01

    Autori arvates ei saa vanemahüvitis jääda ainsaks perepoliitiliseks meetmeks, sest sellega ei ole kõrvaldatud kõik lastekasvatusega seotud raskused ja lahendatud motivatsiooniprobleemi. Diagramm: Kulu lapse kohta

  19. Tartu Ülikool raamatukogus / Tiina Tammet

    Index Scriptorium Estoniae

    Tammet, Tiina, 1971-

    2005-01-01

    Kuni 13 II näitus "R.A.I.S.K." (Radikaalne Agiteeriv Intrigeeriv Sotsiaalne Kunst). Krutskilist ökokunsti teevad Infotankistid, Puhas Rõõm, Piret Räni, Maris Suits, Katrin Tees, Anu Vahtra, Mart Viljus, Ivika Kivi & Sulo Kallas, Taavi Suits, Kai Herkel ja Henry van Noordenburg

  20. Maailma majandusse suurkontsernide kaudu / Tiina Hakman

    Index Scriptorium Estoniae

    Hakman, Tiina

    1996-01-01

    Maailma suurfirmade esindused Eestis: Ericsson, ABB, Coca-Cola, McDonalds, Bristol-Meyers Squibb, Neste, Shell. Ilmunud ka: Molodjozh Estonii, 6. aug. 1996, lk. 3; Russkaja Gazeta, 27. aug. 1996, lk. 3

  1. Mis koolilapsel õnneks vaja? / Tiina Jõgeda

    Index Scriptorium Estoniae

    Jõgeda, Tiina, 1962-

    2011-01-01

    Koolielu vaimse tervise konverentsil Tallinnas tehti kokkuvõtteid SEYLE (Saving and Empowering Young Lives in Europe) projekti raames läbi viidud uuringust. Kaheteistkümnes riigis uuriti nii õpilaste kui ka õpetajate eluga rahulolu. Eesti näitajate võrdlus teiste riikidaga

  2. PÖFF kasvatab meeskonda / Tiina Sarv

    Index Scriptorium Estoniae

    Sarv, Tiina, 1949-

    2006-01-01

    9. mail sõlmisid Tartu Ülikooli Viljandi Kultuuriakadeemia ja Tallinna Pimedate Ööde Filmifestival Viljandis koostöölepingu, mille alusel hakkavad akadeemia tudengid tegema PÖFF-il õppepraktikat

  3. PÖFF kasvatab meeskonda / Tiina Sarv

    Index Scriptorium Estoniae

    Sarv, Tiina, 1949-

    2006-01-01

    9. mail sõlmisid Viljandi Kultuuriakadeemia ja Tallinna Pimedate Ööde Filmifestival Viljandis koostöölepingu, mille põhjal hakkavad akadeemia kultuurikorralduse ja teatrikunsti visuaaltehnoloogia tudengid tegema PÖFF-il õppepraktikat

  4. Šoti kunstnik Tallinnas / Tiina Tammet

    Index Scriptorium Estoniae

    Tammet, Tiina, 1971-

    1998-01-01

    9. veebruarist Draakoni galeriis avatud šoti kunstniku Charles Cusick Smithi (1957) tööde näitusest. Glasgow's sündinud kunstnik ja disainer on pühendanud end teatrile. 12. veebr. "Estonias" esietendunud M. Murdmaa "Romeo ja Julia" on Smithi kujundatud. Ka kunstniku vabalooming on inspireeritud teatrist.

  5. Agenda 21 / Tiina Gaškov

    Index Scriptorium Estoniae

    Gaškov, Tiina

    2000-01-01

    Kuidas säästva eluviisi põhimõtteid ellu viia, sellega on tegelnud PHARE INTERREG õpilaste keskkonnaprojekt "3+3". Projekti elluviijateks olid koos Soome partneritega täiendusõppekeskuse Teave töörühm eesotsas Ene Kalmuse ja Karl Kaasikoviga. "3+3" tähendab, et koostööd, koolitust, kogemustevahetust hakkasid arendama kolm maakonda Eestist (Ida- ja Lääne-Viru- ning Jõgevamaa) ja Soomest Ita-Uusimaa, Kymenlaakso ja Päijät-Häme

  6. Hea haridus vajab stabiilsust / Tiina Oraste

    Index Scriptorium Estoniae

    Oraste, Tiina

    2008-01-01

    Seadusest, mis annab koolidirektoritele tagasi tähtajatu töölepingu. Ilmunud ka Sakala 16. aprill 2008, lk. 2, pealkiri kujul: stabiilsuses peitub arengujõud ; Meie Maa 16. aprill 2008, lk. 2 ; Nädaline 17. aprill 2008, lk. 4 ; Vooremaa 17. aprill 2008, lk. 2 ; Elva Postipoiss 19. aprill 2008, lk. 4 Järva Teataja 19. aprill 2008, lk. 2 ; Koit 24. aprill 2008, lk. 6

  7. Risk factors for motor neuron diseases : genes, environment and lifestyle

    NARCIS (Netherlands)

    Sutedja, N.A.

    2010-01-01

    The main focus of this thesis is to identify susceptibility factors in diseases affecting the motor neuron: both motor neuron disease (MND), in which primarily the cell body is affected, and multifocal motor neuropathy (MMN), in which primarily the axon is affected, are covered. Due to its

  8. Rare genetic variation in UNC13A may modify survival in amyotrophic lateral sclerosis

    NARCIS (Netherlands)

    Gaastra, Benjamin; Shatunov, Aleksey; Pulit, Sara; Jones, Ashley R; Sproviero, William; Gillett, Alexandra; Chen, Zhongbo; Kirby, Janine; Fogh, Isabella; Powell, John F; Leigh, P Nigel; Morrison, Karen E; Shaw, Pamela J; Shaw, Christopher E; van den Berg, Leonard H; Veldink, Jan H; Lewis, Cathryn M; Al-Chalabi, Ammar

    2016-01-01

    Our objective was to identify whether rare genetic variation in amyotrophic lateral sclerosis (ALS) candidate survival genes modifies ALS survival. Candidate genes were selected based on evidence for modifying ALS survival. Each tail of the extreme 1.5% of survival was selected from the UK MND DNA

  9. The Genetics of Monogenic Frontotemporal Dementia

    Directory of Open Access Journals (Sweden)

    Leonel T. Takada

    Full Text Available ABSTRACTAround 10-15% of patients diagnosed with frontotemporal dementia (FTD have a positive family history for FTD with an autosomal dominant pattern of inheritance. Since the identification of mutations in MAPT(microtubuleassociated protein tau gene in 1998, over 10 other genes have been associated with FTD spectrum disorders, discussed in this review. Along with MAPT, mutations in GRN(progranulin and C9orf72(chromosome 9 open reading frame 72 are the most commonly identified in FTD cohorts. The association of FTD and motor neuron disease (MND can be caused by mutations in C9orf72and other genes, such as TARDBP(TAR DNA-binding protein, FUS(fused in sarcoma, UBQLN2(ubiquilin 2. Multisystem proteinopathy is a complex phenotype that includes FTD, Paget disease of the bone, inclusion body myopathy and MND, and can be due to mutations in VCP(valosing containing protein and other recently identified genes.

  10. Design and implementation of a hybrid MPI-CUDA model for the Smith-Waterman algorithm.

    Science.gov (United States)

    Khaled, Heba; Faheem, Hossam El Deen Mostafa; El Gohary, Rania

    2015-01-01

    This paper provides a novel hybrid model for solving the multiple pair-wise sequence alignment problem combining message passing interface and CUDA, the parallel computing platform and programming model invented by NVIDIA. The proposed model targets homogeneous cluster nodes equipped with similar Graphical Processing Unit (GPU) cards. The model consists of the Master Node Dispatcher (MND) and the Worker GPU Nodes (WGN). The MND distributes the workload among the cluster working nodes and then aggregates the results. The WGN performs the multiple pair-wise sequence alignments using the Smith-Waterman algorithm. We also propose a modified implementation to the Smith-Waterman algorithm based on computing the alignment matrices row-wise. The experimental results demonstrate a considerable reduction in the running time by increasing the number of the working GPU nodes. The proposed model achieved a performance of about 12 Giga cell updates per second when we tested against the SWISS-PROT protein knowledge base running on four nodes.

  11. An Exploratory Study of Software Cost Estimating at the Electronic Systems Division.

    Science.gov (United States)

    1976-07-01

    action’. to improve the software cost Sestimating proces., While thin research was limited to the M.nD onvironment, the same types of problema may exist...Methods in Social Science. Now York: Random House, 1969. 57. Smith, Ronald L. Structured Programming Series (Vol. XI) - Estimating Software Project

  12. A Framework for Failure? The Impact of Short Tour Lengths and Separate National Command and Control on British Operational Art and Coalition Warfare in Iraq, 2003-2009

    Science.gov (United States)

    2013-12-10

    frame the problem.54 This is a clear example of cognitive dissonance and highlights the intellectual confusion that had emerged in senior British...to explicitly express complete satisfaction with PJHQ and the command and control framework) came from LTG Riley, CG MND (SE) from Dec 04-Jun 05: LTG

  13. Studies on motor neuron disease with cranial magnetic resonance imaging

    International Nuclear Information System (INIS)

    Mitsui, Yoshiyuki; Takahashi, Mitsuo; Nakamura, Yusaku; Kitaguchi, Masataka; Yagi, Yuji

    1992-01-01

    The present study was performed to examine the pyramidal tracts of the brain in both 51 normal subjects (21 male and 30 female subjects; mean age of 43.5±16.1 years) and 12 patients with motor neuron disease (6 male and 6 female patients; mean age of 57.4±7.9 years), using the magnetic resonance imaging (MRI). The 12 patients with motor neuron disease (MND) comprised 7 suffering from spinal progressive muscular atrophy (SPMA) and 5 from amyotrophic lateral sclerosis (ALS). The MRI used in this study was of both short spin echo and long spin echo sequence. Of the 52 normal subjects, 24 of them (47%) had the T2 prolonged small areas (high signal intensity areas) at the posterior limb of internal capsule. These findings were not found in the normal subjects over fifty years old. No similar finding was detected in the pyramidal tracts except the posterior limb of internal capsule. On the other hand, 8 patients with MND (67%) proved to have the high signal intensity areas in the pyramidal tracts. Moreover, these high intensity areas were extended from the crus cerebri to corona radiata in 7 patients (58%). In all patients with ALS, these areas were extended in whole areas of the pyramidal tracts, and the similar findings were also found in two patients with SPMA. These findings were demonstrated to be more extensive than those in the normal subjects. The results thus obtained warrant us to conclude that cranial MRI is useful to detect the degeneration of the pyramidal tracts of MND patients. (author)

  14. Kiviõli linnaväljaku avalik arhitektuurivõistlus = Kiviõli town square open architecture competition / Tiit Sild

    Index Scriptorium Estoniae

    Sild, Tiit, 1977-

    2006-01-01

    Arhitektuurivõistluse eesmärgist, premeeritud töödest. Tulemused: I preemia - Tiina Skolimowski, Kai Süda, Risto Parve, töö "Figuur", II - Karli Luik, Ralf Lõoke, Maarja Kask (AB Salto), töö "Saarestik", III - Jaak-Adam Looveer, Toomas Paaver, Lauri Saar, Indrek Järve, Tõnu Laanemäe (AB Paik Arhitektid), töö "Mult", ergutuspreemia - Ott Kadarik, Villem Tomiste, Mihkel Tüür, Kaiko Kivi, Krista Saluveer (AB Kosmos), töö "Sammal"

  15. ID-pilet teeb Tallinnas võidukäiku / Anneli Lepp

    Index Scriptorium Estoniae

    Lepp, Anneli

    2006-01-01

    Vt. ka Postimees : na russkom jazõke 12. jaan. lk 3. Tallinna transpordiameti peaökonomisti Mart Moosuse sõnul moodustas ID-pilet 60,7% ühistranspordi piletituludest, Tartus oli vastav näitaja aga alla 1%. Tartut teenindava bussifirma AS Connex Eesti finantsjuht Tiina Telling peab suure erinevuse põhjuseks asjaolu, et Tallinnas on ID-pilet paberpiletist 40-88% soodsam, Tartus hinnavahe aga puudub või on lausa negatiivne ID-pileti kahjuks. Lisa: ID-pilet

  16. Short Outlines of Books by Estonian authors / Rutt Hinrikus

    Index Scriptorium Estoniae

    Hinrikus, Rutt, 1946-

    2007-01-01

    Tutvustus: Miljutina, Tamara. Inimesed minu elus. Tallinn : Varrak, 2007 ; Soosaar, Enn. Isa ja aeg. Tallinn : Kultuurileht, 2007. (Loomingu Raamatukogu ; 5) ; Paju, Imbi. Tõrjutud mälestused. Tallinn : Eesti Entsüklopeediakirjastus, 2007 ; Kaplinski, Jaan. Seesama jõgi. Tallinn : Vagabund, 2007 ; Laanem, Tiina. Väikesed vanamehed. Tallinn : Eesti Päevalehe Kirjastus, 2007 ; Vaarandi, Debora. Aastad ja päevad. Tallinn : Tänapäev, 2006 ; Berg, Maimu. Unustatud inimesed. Tallinn : Tuum, 2007 ; Heinsaar, Mehis. Rändaja õnn. Tallinn : Verb, 2007

  17. Virtuaalitodellisuus matkailumarkkinoinnin välineenä: konseptin muotoilu Clarion Hotelille

    OpenAIRE

    Riihimäki, Marjut

    2016-01-01

    Tämän työn aiheena on suunnitella konsepti virtuaalilasien käyttöympäristöksi Clarion-hotelliketjun markkinoinnin tarpeisiin. Opinnäytetyön toimeksiantaja on Turbiini Yrityskiihdyttämö ja ohjaajanani toimii Turbiinin advisor Tiina Vuorio. Tavoitteena on ensin tutustua olemassaoleviin teknologioihin ja tuotantotapoihin sekä keskustella alan toimijoiden kanssa ja soveltaa saatua tietoa konseptin suunnittelussa. Tämä työ perustelee, miksi etenkin matkailualalla VR-markki- nointiin tulisi tutustu...

  18. Meie nominendid

    Index Scriptorium Estoniae

    2005-01-01

    Areeni kultuuripreemia žürii tutvustab nominente: kunstikoguja Jaan Manitski, fotograaf Peeter Laurits, lavastaja Ain Mäeots, maalikunstnik Peeter Mudist, fotograaf Tiit Lepp, graafik Kristjan Mändmaa, metallikunstnik Ivar Kaasik, arhitekt Arne Maasik, PÖFFi korraldaja Tiina Lokk, tantsumanager Priit Raud, teatrijuht, lavastaja Peeter Jalakas, režissöör Mark Soosaar, lavastaja Tiit Ojasoo, kirjanikud Jaan Kaplinski, Hando Runnel, ajaloolane Magnus Ilmjärv, muusik Aivar Tõnso, disainer Lazer, helilooja Rein Fuks, hip hop ansambel Toe Tag

  19. ERKÜ valimiste tulemused

    Index Scriptorium Estoniae

    2006-01-01

    8. aprilli koosolekul kinnitas valimiste peakomitee XIX Esinduskogu liikmed: Mati Kõiva, Ylo Anson, Juhan Simonson, Airi Vaga, Gilda M. Karu, Taavo Virkhaus, Marju Rink-Abel, Markus Vaga, Eric Suuberg, Endel Reinpõld, Jaak Juhansoo, Ülle Ederma, Lya Karm, Heino Jõgis, Kersti Linask, Jaak Rakfeldt, Erik Puskar, Jüri Linask, Viiu Vanderer, Andres Kurrik, Mati Valdek Laan, Ilmar Vanderer, Henno Uus, Jüri Tults, Urmas Wompa, Astrid Jaanson, Jüri Virkus, Lilian G. G. Bein, Tiina Harris, Tõnu Vanderer

  20. Tarbekunsti- ja Disainimuuseum taas avatud

    Index Scriptorium Estoniae

    2005-01-01

    2. VI avati rekonstrueeritud muuseumihoone. Rekonstrueerimisprojekti autorid: Arhitektuuriagentuuri arhitekt Inga Raukas, sisearhitekt Monika Löve. Ehitustööd: Rihti Projekt. Avatud nahakunstinäitus "Järjehoidja" (kuraator Airi Ligi, kujundaja Siiri Nõva, näha saab ka nahakunsti üliõpilaste töid; filmiprogramm: Maya Yonesho "Üks uks", "Ecce libri" Pille Kivihallist, Tiina Piisangust ja Maarja Unduskist) ja rahvusvaheline köitekunstinäitus "Scripta manent III. Maailma parim asi", kujundaja Lennart Mänd

  1. Millimeter Wave Attenuation in Moist Air: Laboratory Measurements and Analysis.

    Science.gov (United States)

    1984-03-01

    generation of incoherent noise, Mnd wavelengths. (e) scintillitions due to random fluctuations of the medium in space and time. The array of mathematical ...calculations are for observations in the zenith direction free air is very empty. The molecular radius r -1.5 x ICI-4 Lem. groud lvel Coaic aditio of

  2. Amyotrophic lateral sclerosis presenting with orthopnea in a patient with COPD and obstructive sleep apnea

    Directory of Open Access Journals (Sweden)

    T.L.N. Swamy

    2011-01-01

    Full Text Available Amyotrophic lateral sclerosis (ALS, also known as motor neuron disease (MND is a relentlessly progressive neurological disorder causing peripheral muscular weakness and resultant respiratory failure. In this article, we report a case of ALS with chronic obstructive pulmonary disease (COPD and obstructive sleep apnea (OSA with orthopnea as initial symptoms.

  3. Review of Indigenous Health Curriculum in Nutrition and Dietetics at One Australian University: An Action Research Study

    Science.gov (United States)

    Wilson, Annabelle M.; Mehta, Kaye; Miller, Jacqueline; Yaxley, Alison; Thomas, Jolene; Jackson, Kathryn; Wray, Amanda; Miller, Michelle D.

    2015-01-01

    This article describes a review undertaken in 2012-2013 by Nutrition and Dietetics, Flinders University, to assess the Indigenous health curriculum of the Bachelor of Nutrition and Dietetics (BND) and Masters of Nutrition and Dietetics (MND). An action research framework was used to guide and inform inquiry. This involved four stages, each of…

  4. Mutant ApoA-1 Amyloidosis in a Family of Five Siblings With Motor Neuron Disease and Dementia

    DEFF Research Database (Denmark)

    Vrethema, Magnus; Mucchiano, Gerd Ingrid

    2011-01-01

    We present a family of fi ve siblings in which three brothers died of motor neuron disease (MND) and in two of them concomitant with dementia. A fourth brother died of myocardial infarction and was found to have extensive aortic intimal apolipoprotein A-1 (ApoA-1) derived amyloid deposits and apo...

  5. Handwriting, Visuomotor Integration, and Neurological Condition at School Age

    Science.gov (United States)

    Van Hoorn, Jessika F.; Maathuis, Carel G. B.; Peters, Lieke H. J.; Hadders-Algra, Mijna

    2010-01-01

    Aim: The study investigated the relationships between handwriting, visuomotor integration, and neurological condition. We paid particular attention to the presence of minor neurological dysfunction (MND). Method : Participants were 200 children (131 males, 69 females; age range 8-13y) of whom 118 received mainstream education (mean age 10y 5mo, SD…

  6. Tendentsid sisearhitektuuris : Eesti Sisearhitektide Liidu aastapreemiad 2004 / Maris Kerge

    Index Scriptorium Estoniae

    Kerge, Maris

    2005-01-01

    ESL aastapreemid 2004: kodu interjöör - villa Miidurannas, Katrin ja Argo Vaikla, Tiina Teng, Vaikla Disain, projekti juhtimine: Ahti Väin; ühiskondlik interjöör - SPA Hotell Georg Ots Kuressaares, Liisi Murula, Raili Paling, KOKO Arhitektid; ajalooline interjöör - Tartu Mänguasjamuuseum, Tea Tammelaan, Krista Lepland, Malle Jürgenson, Laika, Belka & Strelka; vormipreemia seeriatoode - tool "John", Toivo Raidmets, tootja OÜ Toivo; tegevuspreemia - Disaini- ja Arhitektuurigalerii asutamise ja käigushoidmise eest, Maile Grünberg. Nominentide loetelu

  7. ANTI-DISCRIMINATORY PRACTICE AND COMMUNITY DEVELOPMENT : A case study of a clubhouse community

    OpenAIRE

    Louko, Tiina

    2011-01-01

    Louko, Tiina. Anti-discriminatory practice and community development - A case study of a clubhouse community. Järvenpää, Spring 2011, 54 p. Diaconia University of Applied Sciences, Diak South Järvenpää. Degree Programme in Social Services. Bachelor´s Degree in Social Services. This study was conducted in the context of Eastern Helsinki Clubhouse, which is a community for mental health rehabilitees. The purpose of the research was to describe the clubhouse community from the aspects o...

  8. Prantsuse pidu Berliinis / Tiit Tuumalu

    Index Scriptorium Estoniae

    Tuumalu, Tiit, 1971-

    2001-01-01

    Euroopa Filmiakadeemia auhinnatseremooniast. Parim film - prantslaste "Amélie", parim režissöör - sama filmi looja Jean-Pierre Jeunet ning parim operaator Bruno Delbonnel on samuti sama filmi oma. Parim naisnäitleja on prantslanna Isabelle Huppert austerlase Michael Haneke filmist "Klaveriõpetaja" ja meesnäitleja Ben Kingsley Suurbritannia-Hispaania ühistöös "Seksikas tõbras". Tiina Loki sõnul näeb enamikku neist filmidest ka praegu käimasoleval Pimedate Ööde Filmifestivalil

  9. Transition from the adiabatic to the sudden limit in core-electron photoemission

    Science.gov (United States)

    Hedin, Lars; Michiels, John; Inglesfield, John

    1998-12-01

    Experimental results for core-electron photoemission Jk(ω) are often compared with the one-electron spectral function Ac(ɛk-ω), where ω is the photon energy, ɛk is the photoelectron energy, and the optical transition matrix elements are taken as constant. Since Jk(ω) is nonzero only for ɛk>0, we must actually compare it with Ac(ɛk-ω)θ(ɛk). For metals Ac(ω) is known to have a quasiparticle (QP) peak with an asymmetric power-law [theories of Mahan, Nozières, de Dominicis, Langreth, and others (MND)] singularity due to low-energy particle-hole excitations. The QP peak starts at the core-electron energy ɛc, and is followed by an extended satellite (shakeup) structure at smaller ω. For photon energies ω just above threshold, ωth=-ɛc, Ac(ɛk-ω)θ(ɛk) as a function of ɛk (ω constant) is cut just behind the quasiparticle peak, and neither the tail of the MND line nor the plasmon satellites are present. The sudden (high-energy) limit is given by a convolution of Ac(ω) and a loss function, i.e., by the Berglund-Spicer two-step expression. Thus Ac(ω) alone does not give the correct photoelectron spectrum, neither at low nor at high energies. We present an extension of the quantum-mechanical (QM) models developed earlier by Inglesfield, and by Bardyszewski and Hedin to calculate Jk(ω). It includes recoil and damping, as well as shakeup effects and extrinsic losses, is exact in the high-energy limit, and allows calculations of Jk(ω) including the MND line and multiple plasmon losses. The model, which involves electrons coupled to quasibosons, is motivated by detailed arguments. As an illustration we have made quantitative calculations for a semi-infinite jellium with the density of aluminum metal and an embedded atom. The coupling functions (fluctuation potentials) between the electron and the quasibosons are related to the random-phase-approximation dielectric function, and different levels of approximations are evaluated numerically. The differences

  10. Influence of extractable soil manganese on oxidation capacity of different soils in Korea

    Science.gov (United States)

    Chon, Chul-Min; Kim, Jae Gon; Lee, Gyoo Ho; Kim, Tack Hyun

    2008-08-01

    We examined the relationship between soil oxidation capacity and extractable soil manganese, iron oxides, and other soil properties. The Korean soils examined in this study exhibited low to medium Cr oxidation capacities, oxidizing 0.00-0.47 mmol/kg, except for TG-4 soils, which had the highest capacity for oxidizing added Cr(III) [>1.01 mmol/kg of oxidized Cr(VI)]. TG and US soils, with high Mn contents, had relatively high oxidation capacities. The Mn amounts extracted by dithionite-citrate-bicarbonate (DCB) (Mnd), NH2OH·HCl (Mnh), and hydroquinone (Mnr) were generally very similar, except for the YS1 soils, and were well correlated. Only small proportions of either total Mn or DCB-extractable Mn were extracted by NH2OH·HCl and hydroquinone in the YS1 soils, suggesting inclusion of NH2OH·HCl and hydroquinone-resistant Mn oxides, because these extractants are weaker reductants than DCB. No Cr oxidation test results were closely related to total Mn concentrations, but Mnd, Mnh, and Mnr showed a relatively high correlation with the Cr tests ( r = 0.655-0.851; P Mnh were better correlated with the Cr oxidation tests than was the Mnr concentration, suggesting that the oxidation capacity of our soil samples can be better explained by Mnd and Mnh than by Mnr. The first component in principal components analysis indicated that extractable soil Mn was a main factor controlling net Cr oxidation in the soils. Total soil Mn, Fe oxides, and the clay fraction are crucial for predicting the mobility of pollutants and heavy metals in soils. The second principal component indicated that the presence of Fe oxides in soils had a significant relationship with the clay fraction and total Mn oxide, and was also related to heavy-metal concentrations (Zn, Cd, and Cu, but not Pb).

  11. Age-Related Uptake of Heavy Metals in Human Spinal Interneurons.

    Directory of Open Access Journals (Sweden)

    Roger Pamphlett

    Full Text Available Toxic heavy metals have been implicated in the loss of spinal motoneurons in amyotrophic lateral sclerosis/motor neuron disease (ALS/MND. Motoneuron loss in the spinal anterior horn is severe in ALS/MND at the time of death, making this tissue unsuitable for examination. We therefore examined spinal cords of people without muscle weakness to look for any presence of heavy metals that could make these neurons susceptible to damage. Spinal cord samples from 50 individuals aged 1-95 y who had no clinical or histopathological evidence of spinal motoneuron loss were studied. Seven μm formalin-fixed paraffin-embedded sections were stained for heavy metals with silver nitrate autometallography (AMGHM which detects intracellular mercury, silver or bismuth. Neurons in the spinal cord were classified as interneurons or α-motoneurons based on their site and cell body diameter. Spinal interneurons containing heavy metals were present in 8 of 24 people (33% aged 61-95 y, but not at younger ages. These AMGHM interneurons were most numerous in the lumbar spinal cord, with moderate numbers in the caudal cervical cord, few in the rostral cervical cord, and almost none in the thoracic cord. All people with AMGHM interneurons had occasional AMGHM staining in α-motoneurons as well. In one man AMGHM staining was present in addition in dorsomedial nucleus and sensory neurons. In conclusion, heavy metals are present in many spinal interneurons, and in a few α-motoneurons, in a large proportion of older people. Damage to inhibitory interneurons from toxic metals in later life could result in excitotoxic injury to motoneurons and may underlie motoneuron injury or loss in conditions such as ALS/MND, multiple sclerosis, sarcopenia and calf fasciculations.

  12. Vpx overcomes a SAMHD1-independent block to HIV reverse transcription that is specific to resting CD4 T cells.

    Science.gov (United States)

    Baldauf, Hanna-Mari; Stegmann, Lena; Schwarz, Sarah-Marie; Ambiel, Ina; Trotard, Maud; Martin, Margarethe; Burggraf, Manja; Lenzi, Gina M; Lejk, Helena; Pan, Xiaoyu; Fregoso, Oliver I; Lim, Efrem S; Abraham, Libin; Nguyen, Laura A; Rutsch, Frank; König, Renate; Kim, Baek; Emerman, Michael; Fackler, Oliver T; Keppler, Oliver T

    2017-03-07

    Early after entry into monocytes, macrophages, dendritic cells, and resting CD4 T cells, HIV encounters a block, limiting reverse transcription (RT) of the incoming viral RNA genome. In this context, dNTP triphosphohydrolase SAM domain and HD domain-containing protein 1 (SAMHD1) has been identified as a restriction factor, lowering the concentration of dNTP substrates to limit RT. The accessory lentiviral protein X (Vpx) proteins from the major simian immunodeficiency virus of rhesus macaque, sooty mangabey, and HIV-2 (SIVsmm/SIVmac/HIV-2) lineage packaged into virions target SAMHD1 for proteasomal degradation, increase intracellular dNTP pools, and facilitate HIV cDNA synthesis. We find that virion-packaged Vpx proteins from a second SIV lineage, SIV of red-capped mangabeys or mandrills (SIVrcm/mnd-2), increased HIV infection in resting CD4 T cells, but not in macrophages, and, unexpectedly, acted in the absence of SAMHD1 degradation, dNTP pool elevation, or changes in SAMHD1 phosphorylation. Vpx rcm/mnd-2 virion incorporation resulted in a dramatic increase of HIV-1 RT intermediates and viral cDNA in infected resting CD4 T cells. These analyses also revealed a barrier limiting HIV-1 infection of resting CD4 T cells at the level of nuclear import. Single amino acid changes in the SAMHD1-degrading Vpx mac239 allowed it to enhance early postentry steps in a Vpx rcm/mnd-2-like fashion. Moreover, Vpx enhanced HIV-1 infection of SAMHD1-deficient resting CD4 T cells of a patient with Aicardi-Goutières syndrome. These results indicate that Vpx, in addition to SAMHD1, overcomes a previously unappreciated restriction for lentiviruses at the level of RT that acts independently of dNTP concentrations and is specific to resting CD4 T cells.

  13. The Effects of Motor Neurone Disease on Language: Further Evidence

    Science.gov (United States)

    Bak, Thomas H.; Hodges, John R.

    2004-01-01

    It might sound surprising that Motor Neurone Disease (MND), regarded still by many as the very example of a neurodegenerative disease affecting selectively the motor system and sparing the sensory functions as well as cognition, can have a significant influence on language. In this article we hope to demonstrate that language dysfunction is not…

  14. Synthèse: Revue des Sciences et de la Technologie - Vol 17 (2008)

    African Journals Online (AJOL)

    Modélisation numérique d'un phénomène mécanique (TRIP) induit par une transformation martensitique dans l'acier 16MND5 · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. S Mefta, L Taleb, F Barbe, F Sidoroff, 73-84 ...

  15. Mechanical cough augmentation techniques in amyotrophic lateral sclerosis/motor neuron disease

    OpenAIRE

    Rafiq, M.K.; Bradburn, M.; Mustfa, N.; Mcdermott, C.J.; Annane, D.

    2016-01-01

    © 2016 The Cochrane Collaboration.This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess the effects of mechanical insufflator/exsufflator (MI-E) and the breath-stacking technique for reducing morbidity and mortality and enhancing quality of life in people with amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND).

  16. [History of hereditary motor and sensory neuropathy with proximal dominant involvement (HMSN-P)].

    Science.gov (United States)

    Takashima, Hiroshi

    2013-01-01

    We established a new disease autosomal dominant hereditary motor and sensory neuropathy with proximal dominant involvement (HMSNP) in 1997, in Okinawa, Japan. This disease is characterized by proximal dominant neurogenic atrophy with fasciculations, painful muscle cramp, obvious sensory nerve involvement, areflexia, high incidence of elevated creatine kinase levels, hyperlipidemia and hyperglycemia. (MIM %604484). HMSNP is so called or HMSNO (HMSN OKINAWA type),. These clinical features resembled those of Kennedy-Alter-Sung syndrome. Most HMSNP patients have severe muscle atrophy and finally the tracheostomy and artificial ventilation are required. Therefore, we initially thought to classify HMSNP into a subtype of motor neuron disease (MND) like familial amyotrophic lateral sclerosis (FALS) or spinal muscular atrophy (SMA). However, the general consensus for MND was no sensory involvement. Therefore, as the disease showed severe sensory involvement, we categorized HMSNP in subtype of HMSN at that time. We also reported the pathology of HMSNP, showing severely decreased anterior horn cells, decreased posterior horn cells, and loss of posterior funiculus in the spinal cord.

  17. Therapeutic opportunities and challenges of induced pluripotent stem cells-derived motor neurons for treatment of amyotrophic lateral sclerosis and motor neuron disease

    Institute of Scientific and Technical Information of China (English)

    Manoj Kumar Jaiswal

    2017-01-01

    Amyotrophic lateral sclerosis (ALS) and motor neuron diseases (MNDs) are progressive neurodegenera-tive diseases that affect nerve cells in the brain affecting upper and lower motor neurons (UMNs/LMNs), brain stem and spinal cord.The clinical phenotype is characterized by loss of motor neurons (MNs), mus-cular weakness and atrophy eventually leading to paralysis and death due to respiratory failure within 3–5 years after disease onset. No effective treatment or cure is currently available that halts or reverses ALS and MND except FDA approved drug riluzole that only modestly slows the progression of ALS in some patients. Recent advances in human derived induced pluripotent stem cells have made it possible for the first time to obtain substantial amounts of human cells to recapitulate in vitro"disease in dish"and test some of the underlying pathogenetic mechanisms involved in ALS and MNDs. In this review, I discussed the opportunities and challenges of induced pluropotent stem cells-derived motor neurons for treatment of ALS and MND patients with special emphasis on their implications in finding a cure for ALS and MNDs.

  18. Therapeutic opportunities and challenges of induced pluripotent stem cells-derived motor neurons for treatment of amyotrophic lateral sclerosis and motor neuron disease.

    Science.gov (United States)

    Jaiswal, Manoj Kumar

    2017-05-01

    Amyotrophic lateral sclerosis (ALS) and motor neuron diseases (MNDs) are progressive neurodegenerative diseases that affect nerve cells in the brain affecting upper and lower motor neurons (UMNs/LMNs), brain stem and spinal cord. The clinical phenotype is characterized by loss of motor neurons (MNs), muscular weakness and atrophy eventually leading to paralysis and death due to respiratory failure within 3-5 years after disease onset. No effective treatment or cure is currently available that halts or reverses ALS and MND except FDA approved drug riluzole that only modestly slows the progression of ALS in some patients. Recent advances in human derived induced pluripotent stem cells have made it possible for the first time to obtain substantial amounts of human cells to recapitulate in vitro " disease in dish " and test some of the underlying pathogenetic mechanisms involved in ALS and MNDs. In this review, I discussed the opportunities and challenges of induced pluropotent stem cells-derived motor neurons for treatment of ALS and MND patients with special emphasis on their implications in finding a cure for ALS and MNDs.

  19. Rupther: a simulation approach applied to a PWR vessel failure during a severe accident

    International Nuclear Information System (INIS)

    Mongabure, Ph.; Nicolas, L.; Devos, J.

    2000-01-01

    The Rupther program (Rupture Under Thermal Conditions) is a part of the international researches on severe accidents in the PWR type reactors. The aim of the program is the definition of failure simulation validated by experimental data on vessel steel 16MND5 mechanical properties. The paper presents the program and the first results. (A.L.B.)

  20. Negotiating the Nation in History: the Swedish State Approval Scheme for Textbooks and Teaching Aids from 1945 to 1983

    Science.gov (United States)

    Elmersjö, Henrik Åström

    2016-01-01

    This article explores the discussions concerning history textbooks that occurred within the Swedish State Approval Scheme for Textbooks (Statens läroboksnämnd) from 1945 to 1983. By focusing on the negotiation of nationhood and the process of textbook approval as an arena for the renegotiation of ways in which history was taught in schools, the…

  1. Kolleegist parem / Andres Kurg

    Index Scriptorium Estoniae

    Kurg, Andres, 1975-

    2006-01-01

    Eesti Sisearhitektide Liidu aastapreemiad 2005: parima ühiskondliku interjööri preemia võitis Pääsküla raamatukogu (Katrin Kaevats, Urmas Muru, Peeter Pere), näitusekujunduse preemia sai Maanteemuuseum (Krista Lepland, Malle Jürgenson, Tea Tammelaan, OÜ Laika, Belka & Strelka), ajaloolise interjööri preemia läks renoveeritud Estonia teatrile (Juta Lember, Aulo Padar), publitsistikapreemia sai Leila Pärtelpoja raamat "Pööningul", teise ühiskondliku ruumi preemia võitis TTP ärihoone Pirital (Meelis Press). Kommentaar Tiina Jõgedalt

  2. Selgusid isamaaliste laulude konkursi võitjad

    Index Scriptorium Estoniae

    2007-01-01

    Eesti Kooriühingu ja kultuuriseltsi Hirvepark korraldatud laulukonkursi võitjad: Sirje Kaasiku laul "Tahan presidendiks" (I preemia laste- ja poistekooride kategoorias), Riine Pajusaare "Õnnelaul" ja "Lambad on kadunud" (II preemia), Alo Ritsingu "Rivilaul" ja Sirje Kaasiku "Ema nimed" (III preemia); segakooride kategoorias Urmas Sisaski "Eestlastele" ja Tiina Kiilaspea "Tähediamendid" (II preemia), Siiri Kaasik "Armastus on suurim" (III preemia); meeskoorilauludest Alo Ritsingu "Mu laul" (II preemia), "Teretus" ja "Kojuigatsus" (III preemia), Erki Meisteri "Roimar" (III preemia), naiskoori de kategoorias Alo Ritsingu "Kevad kumiseb" (III preemia),

  3. Kividraakonid ja kuuvärav / Tiina Tammet

    Index Scriptorium Estoniae

    Tammet, Tiina, 1971-

    2004-01-01

    Hiina aiast. Filosoofilisest tagamaast, aiast kui maailmamudelist, majast ja aiast, kividraakonitest ning igavese elu taimedest. Illustratsiooniks 13 fotot Austraalias Sydneys asuvast Sõpruse aiast (Chinese Garden of Friendship), mis on üks suuremaid hiinlaste poolt loodud aedu väljaspool Hiinat

  4. Paremad preemiatega pärjatud / Tiina Kolk

    Index Scriptorium Estoniae

    Kolk, Tiina

    2008-01-01

    Eesti Sisearhitektide Liidu 2007. aasta preemiad pälvisid: Tartu Lotte lasteaia interjöör (sisearhitektid Malle Jürgenson, Krista Lepland, disainerid Sirli Ehari, Tea Tammelaan); Tartu rokibaar Underground (arhitekt Margus Mänd); Tallinna hotell Telegraaf (sisearhitektid Külli Salum, Riina Harik); Sakubü bürooruumid (sisearhitektid Urmo Vaikla, Tüüne-Kristin Vaikla); Andres Labi ja Janno Roosi disainitud valgusti Labak

  5. Raamat väikerahvaste terminoloogiast / Tiina Leemets

    Index Scriptorium Estoniae

    Leemets, Tiina

    1994-01-01

    Rahvusvahelise terminoloogiainstituudi IITF-i väljaande "Terminology Science and Research" väikekeelte terminoloogia olukorrale pühendatud erinumbrist (nr. 2/1991), kus käsitletakse eesti (Tiiu Erelt, Henn Saari), läti, leedu, ukraina, lapi, islandi, mänksi, iiri, katalaani ja baski oskuskeelt

  6. Uus kodulehekülg avatud! / Tiina Veldi

    Index Scriptorium Estoniae

    Veldi, Tiina

    2001-01-01

    20. märtsil 2001. a. avati Tallinna Pedagoogikaülikooli uus kodulehekülg. Avamisele eelnes aastapikkune koostöö TPÜ ja All Web Industry vahel, kes on uue kodulehekülje kujunduse ja tehnilise teostuse autor

  7. Põhikool gümnaasiumist lahku? / Tiina Annus

    Index Scriptorium Estoniae

    Annus, Tiina, 1948-

    2005-01-01

    Põhikooli ja gümnaasiumiastme lahutamine tähendaks seda, et kaob põhjus varajasteks koolikatseteks, kasvaks lapsevanemate nõudlikkus, väheneks klassikursuse kordajate ning koolist väljalangejate arv. Põhikooli ja gümnaasiumi lahutades loodaks üks eeldus tugevate maakoolide püsimajäämiseks

  8. Kaitseliit loeb torud üle / Tiina Kaalep

    Index Scriptorium Estoniae

    Kaalep, Tiina, 1964-

    1998-01-01

    31. 03. 1997. a. Kaitseliidu ülema käskkirjast nr. 125, mille kohaselt kaitseliitlaste isiklikud relvad tuleb arvele võtta teenistusrelvadena. Postimehe küsimusele vastavad Kaitseliidu ülem kolonelleitnant Lui Jaanson, Kaitseliidu Saaremaa maleva pealik leitnant Mati Vendel, Kaitseliidu Jõgeva maleva pealik leitnant Ants Nurk

  9. Keskkonnasõbralik väikeaed / Tiina Tammet

    Index Scriptorium Estoniae

    Tammet, Tiina, 1971-

    2004-01-01

    Aiakujundaja Stephen Firthi rajatud ökoloogiline aed "After the Lawn" 2004. a. Chelsea aiandusnäitusel. Aiamajake on ehitatud vanadest palkidest ja põrandalaudadest, katus on kaetud kanarbikuga. Istumiskoht on sillutatud kasutatud kiviplaatidega. 4 ill

  10. Värviküllane elujanu / Tiina Tammet

    Index Scriptorium Estoniae

    Tammet, Tiina, 1971-

    2004-01-01

    Suurbritannia Vähiuuringute keskusele loodud Elu Aed 2004. a. Chelsea aiandusnäitusel. Aia kujundasid Jane Hudson & Erik de Maeijer. Mosaiiktee autor Maggy Howarth. Soojades toonides külluslik lilleaed sisendab elujõudu, vabadust ja energiat. 4 ill

  11. DOCOMOMO cream. Modernismi valitud palad / Tiina Tammet

    Index Scriptorium Estoniae

    Tammet, Tiina, 1971-

    2000-01-01

    Raamatust:The modern movement in architecture : selections from the DOCOMOMO registers. Toimetajad Dennis Sharp ja Chaterine Cooke. Rotterdam : Publishers, 2000. Eesti funktsionalismist on teinud kokkuvõtte Piret Lindpere ja Mart Kalm

  12. Tagasi looduse ja inimese juurde / Tiina Abel

    Index Scriptorium Estoniae

    Abel, Tiina, 1951-

    2010-01-01

    Kunstipoliitika ja ametlik kunst. Heroiline alastuse motiiv. 1937. aasta Pariisi maailmanäitus. Väitlused kunsti rahvuslikkuse ja eesti stiili üle. Kunstikool ja kunstiühing Pallas. Prantsuse orientatsiooni süvenemine. Kaks Prantsuse kunstikultuuri manifestatsiooni

  13. 451° Fahrenheiti Eesti moodi / Tiina Tammer

    Index Scriptorium Estoniae

    Tammer, Tiina, 1960-

    2013-01-01

    451° Fahrenheiti on temperatuur, mille juures paber süttib ja põleb. Eestis üle aasta toimunud klaperjaht raamatute, raamatukogude ja kirjastajate ümber paneb küsima: kes tõmbab lõpuks tikku ja süütab esimese raamatu? Autor otsib küsimusele vastuseid

  14. "Scripta" üldpilt on muljetavaldav / Tiina Kolk

    Index Scriptorium Estoniae

    Kolk, Tiina

    2005-01-01

    Rahvusvahelisest köitenäitusest "Scripta manet III" Eesti Tarbekunsti- ja Disainimuuseumis. Osaleb 130 kunstnikku 17 riigist. Näitusega kaasneval konkursil pälvisid Kuldraamatu auhinna eesti kunstnikud Külli Grünbach-Sein, Kaire Olt ja Jaana Päeva

  15. Kontserdid ja etendused toimuvad ikkagi / Tiina Kangro

    Index Scriptorium Estoniae

    Kangro, Tiina, 1961-

    2007-01-01

    Idamaise muusika festivalist "Orient" 2.-8. maini Tallinnas. Edasilükkunud kontsertidest: Vene rockansambli Zemfira kontsert Rock Cafes toimub 28. mail, Filharmoonia Kammerkoori kontsert "Õhtu Arvo Pärdiga" Niguliste kirikus 18. mail. Briti ansambli Pet Shop Bousi kontsert 2. mail, Saxoni kontsert 3. mail

  16. Möödus vaikselt / Tiina Käesel

    Index Scriptorium Estoniae

    Käesel, Tiina, 1943-

    2001-01-01

    Tallinna rakenduskunsti triennaalist 2000 "Omand" Tarbekunstimuuseumis. Kontseptsioon-kujundus: Ketli Tiitsar, Kaire Rannik, Berit Teeäär, Kristi Paap (F.F.F.F.). Paremaid esinejaid. Peaauhind - Eija Mustonen (Soome), auhinnad - Audrius Janushonis (Leedu), Claus Domine Hansen (Taani), Tarbekunstimuuseumi ostuauhind - Aigi Orav, grupi F.F.F.F. auhind - Monika Järg

  17. ISATT konverents: teooria kohtub praktikaga / Tiina Anspal

    Index Scriptorium Estoniae

    Anspal, Tiina

    2015-01-01

    Hariduse koostööpäevade raames toimunud rahvusvahelisest konverentsist, mille eesmärgiks oli tutvustada hariduspraktikale oluliste uuringute tulemusi ja aidata tõstatada koolipraktikast tulenevaid uurimist vajavaid teemasid

  18. ETV katuse all keedeti salaseepi / Tiina Jõgeda

    Index Scriptorium Estoniae

    Jõgeda, Tiina, 1962-

    2011-01-01

    Rahvusringhäälingu (ERR) tootmisteenistuse juhataja Janno-Hans Arro, kes seoses pettustega vallandati augustis ERR-ist, valmistas mitu aastat ette suurejoonelist kodumaist teleseriaali. Seriaali filmiti sel suvel Madeiral. Põhjendustest, miks ETV seda ära osta ei taha

  19. Esimene GSM-võrk Radiolinjal / Tiina Kass

    Index Scriptorium Estoniae

    Kass, Tiina

    2004-01-01

    Ilmunud ka: Delovõje Vedomosti : Infotehnologija 21. apr. lk. 1. Mobiilsideoperaatori Radiolinja Eesti AS-i juht Ants Viira ettevõtte asutamisest 1994. aastal, GSM-võrgu avamisest ja konkurentsist EMT AS-iga. Lisa: Radiolinja kõnehind pole 10 aastaga kuigivõrd muutunud. Vt. samas: Suhkru ja metalliärikad olid esimesed mobiiliomanikud

  20. Majad moodsalt tänavalt / Tiina Tammet

    Index Scriptorium Estoniae

    Tammet, Tiina, 1971-

    2001-01-01

    1927. a. Stuttgarti ehitatud Weissenhofi elamugrupist (Le Corbusier, P. Jeanneret, J. J. P. Oud, M. Stam, W. Gropius, P. Behrens, M. ja B. Taut jt.) ja 1933. a. valminud Vaarika-Maasika t. asumist (A. Volberg, E. J. Kuusik, E. Jacoby, E. Lohk, F. de Vries). Näitus "Moodsad näidisasumid: Weissenhof & Maasika-Vaarika" Rotermanni soolalaos.

  1. Pilkupüüdvad portreed / Tiina Kolk

    Index Scriptorium Estoniae

    Kolk, Tiina

    2010-01-01

    Tutvustatakse järgmisi portreemaale: Johann Köler "Ella von Shultz-Adajewsky portree" (1868), Paul Raud "Autoportree kaabuga" (1900), Ants Laikmaa "Marie Underi portree" (1904), Adamson-Eric "Johannes Semperi portree" (1927), Nikolai Triik "Kunstnik Konrad Mäe portree" (1908)

  2. Põhja-Eesti kirikuelu arengujooni 13.-14. sajandil : millisesse vaimulikku keskkonda tekkis Pirita klooster? / Tiina Kala ; tõlk. Tiina Randviir

    Index Scriptorium Estoniae

    Kala, Tiina

    2007-01-01

    Tallinna piiskopkonna teke ja Põhja-Eesti kirikuelu Taani ajal ning muudatused seoses Põhja-Eesti müügiga Saksa Ordule, millega kaasnesid ordu võimuga seonduvad probleemid - vastuolud ordu ja Liivimaa piiskopkonna vahel, piiskoppide pärinevuse nõue ordu ridadest, kiriku õiguste ja võimaluste piiramine, interdikti kehtestamine ordualadele paavsti poolt pärast Jüriöö ülestõusu

  3. Naisjuhtidega ettevõtete TOP 70

    Index Scriptorium Estoniae

    2003-01-01

    Naisjuhtidega ettevõtete TOP 70. Käibe TOP 30. Käibe kasvu TOP 30. Kasumi TOP 30. Kasumi kasvu TOP 30. Rentaabluse TOP 30. Omakapitali tootlikkuse TOP 30. Nais- ja meesjuhtidega ettevõtted 2001. aasta 500 edukama ettevõtte hulgas. Naistegevjuhtidega firmade TOP 2001 ja 2002. Riigi- ja kohaliku omavalitsuse asutuste naisjuhtide TOP 20. Riigi- ja kohaliku omavalitsuse asutuste eelarve TOP 20. Riigi- ja kohaliku omavalitsuse asutuste töötajate arvu TOP 20. Naistegevjuhtidega firmade osakaal 2001. aastal. Riigi- ja kohaliku omavalitsuse asutuste naisjuhtide aastapalga TOP 20. Kommenteerib Tiina Raitviir.

  4. Eesti proosa 2007 - kultuuri ja tsivilisatsiooni vahel / Peeter Helme

    Index Scriptorium Estoniae

    Helme, Peeter, 1978-

    2008-01-01

    Ülevaade 2007. aasta eesti proosast. Käsitletakse järgimisi autoreid ja nende teoseid: Ene Mihkelson "Katkuhaud", Jaan Kaplinski "Seesama jõgi", Toomas Vint "Mäluauguga naine", Mehis Heinsaar "Rändaja õnn", Maimu Berg "Unustatud inimesed", Mihkel Mutt "Siseemigrant", Vahur Afanasjev "Kaadrid otsustavad", Epp Annus "Sina, Matilda", Ivar Sild "Tantsiv linn", Tiina Laanem "Väikesed vanamehed", Olle Lauli "Niguliste õpilased", Aarne Biin "Linna valitsemine", Jaan Aps ja Joonas Sildre "Hinglõõm". Ka Armin Kõomäe loomingust. Artikli aluseks on Eesti Kirjanduse Seltsi 2007. a. eesti kirjanduse ülevaatekoosolekul peetud ettekanne

  5. Girls Only : kerho tyttöydestä 11-12-vuotiaille tytöille

    OpenAIRE

    Alanen, Tiina; Virtanen, Linda

    2013-01-01

    TIIVISTELMÄ Alanen, Tiina & Virtanen, Linda. Girls Only – kerho tyttöydestä 11–12-vuotiaille tytöille. Diak Etelä, Helsinki, kevät 2013, 61 s., 8 liitettä. Diakonia-ammattikorkeakoulu. Hoitotyön koulutusohjelma Diakonisen hoitotyön suuntautumisvaihtoehto. Sairaanhoitaja (AMK) – diakonissa. Tämän opinnäytetyön tavoitteena on edistää varhaisnuorten tyttöjen terveyttä kristillisessä ympäristössä sekä ideoida uusia menetelmiä seurakunnan var-haisnuorisotyöhön. Hanke toteutettiin työel...

  6. Amelie võlus elurõõmuga / Kristjan Jaak Kangur

    Index Scriptorium Estoniae

    Kangur, Kristjan Jaak

    2001-01-01

    Euroopa Filmiakadeemia auhinnatseremooniast. Parim film - prantslaste "Amélie", parim režissöör - sama filmi looja Jean-Pierre Jeunet ning parim operaator Bruno Delbonnel on samuti sama filmi oma. Elutöö auhinna sai koomikute rühmitus Monty Python. Parim naisnäitleja on prantslanna Isabelle Huppert austerlase Michael Haneke filmist "Klaveriõpetaja" ja meesnäitleja Ben Kingsley Suurbritannia-Hispaania ühistöös "Seksikas tõbras". Tiina Loki sõnul näeb enamikku neist filmidest ka praegu käimasoleval Pimedate Ööde Filmifestivalil

  7. Oskusteabe tarbekunsti-tiritamm / Lylian Meister

    Index Scriptorium Estoniae

    Meister, Lylian, 1966-

    2009-01-01

    Tallinna 5. rakenduskunsti triennaalist. Peanäitus "Know how" Eesti Tarbekunsti- ja Disainimuuseumis kuni 21. 02. 2010 (kuraator Kärt Maran, kujundajad: Ott Kadarik, Tuuli Aule). Kolm võrdset preemiat said Marta Boan (Hispaania), autorite kollektiiv Jaan Evart (Eesti), Julian Hagen (Austria) ja Daniel Maarleveld (Holland) ning Kieren Jones (Suurbritannia). Satelliitnäitused: "EKA Know How. See on imelihtne?" (kuraatorid: Eeva Käsper, Tiina Sarapu) Eesti Kunstiakadeemia galeriis 12. 11.-10. 12. 2009, "Praktiline Kunst ja Kodu" (kuraator Kai Lobjakas, kujundaja Mikk Heinsoo) Hobusepea galeriis 14.-23. 11. 2009

  8. Balti-Kanada uuringute konverents

    Index Scriptorium Estoniae

    2000-01-01

    11. novembril toimus Vilniuse ülikoolis NACSi poolt organiseeritud rahvusvaheline Balti-Kanada uuringute konverents "Rediscovering Canada", mille plenaaristungi võtmekõnelejate seas esinesid Peter McKellac (Kanada suursaadik Balti riikides), professor John Erik Fossum (Põhjamaade Kanada Assotsiatsiooni president) ja Janice Kulyk Keefer (Kanada kirjanik, Guelphi ülikooli professor). Kaheksa töösektsiooni seas enim vastukajasid tekitanud kanada kirjanduse töögrupis esines ettekandega "Estonian Diaspora Writers in the Canadian Literary Context" TPÜ maailmakirjanduse professor Tiina Aunin. Assotsiatsiooni järgmine konverents toimub 2002. aastal Stockholmis : [täistekst

  9. Yritystoiminnan laajentaminen Kissakahvila Purnauskiksessa : opas yrittäjälle

    OpenAIRE

    Lehmus, Ida-Rebecka

    2016-01-01

    Tämä opinnäytetyö on tehty toimeksiantona Kissakahvila Purnauskiksen yrittäjälle, Tiina Aaltoselle. Kissakahvila Purnauskiksen toimintaa aiotaan laajentaa Ouluun, joten työssä keskitytään teemoihin laajennustoimiin liittyen. Työn painopisteen kartoittami-seksi tehtiin alkuselvitys yrittäjän kanssa tämän tarpeista ja toiveista. Päätökset lopulli-sesta laajentamistavasta, aikataulusta ja rahoituskeinoista ovat vielä kesken, joten työn rajaus oli kirjoittajan päätettävissä. Opinnäytetyön tar...

  10. Hamilton Park Care Facility, Balrothery, Balbriggan, Co. Dublin.

    LENUS (Irish Health Repository)

    Galvin, Miriam

    2018-01-27

    Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease (MND), is a debilitating terminal condition. Informal caregivers are key figures in ALS care provision. The physical, psychological and emotional impact of providing care in the home requires appropriate assistance and support. The objective of this analysis is to explore the needs of informal ALS caregivers across the caregiving course.

  11. Estimating the ROI on Implementation of RFID at the Ammunition Storage Warehouse and the 40th Supply Depot: KVA as a Methodology

    Science.gov (United States)

    2009-12-01

    Balanced Scorecard CAPM Capital Asset Pricing Model DIS Defense Information System DoD Department of...Measurement Tool (PMT) is the Balanced Scorecard (BSC) based on critical success factors and key performance indicators. The MND has referred to Jung’s...authors can replicate the methodology for multiple projects to generate a portfolio of projects. Similar to the Capital Asset Pricing Model ( CAPM ) or

  12. Needs of informal caregivers across the caregiving course in amyotrophic lateral sclerosis: a qualitative analysis.

    LENUS (Irish Health Repository)

    Galvin, Miriam

    2018-01-27

    Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease (MND), is a debilitating terminal condition. Informal caregivers are key figures in ALS care provision. The physical, psychological and emotional impact of providing care in the home requires appropriate assistance and support. The objective of this analysis is to explore the needs of informal ALS caregivers across the caregiving course.

  13. Structure and DNA-binding of meiosis-specific protein Hop2

    Science.gov (United States)

    Zhou, Donghua; Moktan, Hem; Pezza, Roberto

    2014-03-01

    Here we report structure elucidation of the DNA binding domain of homologous pairing protein 2 (Hop2), which is important to gene diversity when sperms and eggs are produced. Together with another protein Mnd1, Hop2 enhances the strand invasion activity of recombinase Dmc1 by over 30 times, facilitating proper synapsis of homologous chromosomes. However, the structural and biochemical bases for the function of Hop2 and Mnd1 have not been well understood. As a first step toward such understanding, we recently solved the structure for the N-terminus of Hop2 (1-84) using solution NMR. This fragment shows a typical winged-head conformation with recognized DNA binding activity. DNA interacting sites were then investigated by chemical shift perturbations in a titration experiment. Information of these sites was used to guide protein-DNA docking with MD simulation, revealing that helix 3 is stably lodged in the DNA major groove and that wing 1 (connecting strands 2 and 3) transiently comes in contact with the minor groove in nanosecond time scale. Mutagenesis analysis further confirmed the DNA binding sites in this fragment of the protein.

  14. 75 FR 12802 - Notice of Availability of Calendar Year 2011 Competitive Grant Funds

    Science.gov (United States)

    2010-03-17

    ... administering Federal funds provided for civil legal services to low-income people. LSC hereby announces the...-2, NNM-4 New York NY-9 North Dakota ND-3, MND, NND-3 Ohio OH-20, OH-18, OH-21, OH-23, MOH Oklahoma NOK-1 Pennsylvania PA-1, PA-24, MPA Puerto Rico PR-2 South Dakota SD-2, SD-4, MSD, NSD-1 Tennessee TN...

  15. A mixed methods evaluation of the maternal-newborn dashboard in Ontario: dashboard attributes, contextual factors, and facilitators and barriers to use: a study protocol.

    Science.gov (United States)

    Dunn, Sandra; Sprague, Ann E; Grimshaw, Jeremy M; Graham, Ian D; Taljaard, Monica; Fell, Deshayne; Peterson, Wendy E; Darling, Elizabeth; Harrold, JoAnn; Smith, Graeme N; Reszel, Jessica; Lanes, Andrea; Truskoski, Carolyn; Wilding, Jodi; Weiss, Deborah; Walker, Mark

    2016-05-04

    There are wide variations in maternal-newborn care practices and outcomes across Ontario. To help institutions and care providers learn about their own performance, the Better Outcomes Registry & Network (BORN) Ontario has implemented an audit and feedback system, the Maternal-Newborn Dashboard (MND), for all hospitals providing maternal-newborn care. The dashboard provides (1) near real-time feedback, with site-specific and peer comparison data about six key performance indicators; (2) a visual display of evidence-practice gaps related to the indicators; and (3) benchmarks to provide direction for practice change. This study aims to evaluate the effects of the dashboard, dashboard attributes, contextual factors, and facilitation/support needs that influence the use of this audit and feedback system to improve performance. The objectives of this study are to (1) evaluate the effect of implementing the dashboard across Ontario; (2) explore factors that potentially explain differences in the use of the MND among hospitals; (3) measure factors potentially associated with differential effectiveness of the MND; and (4) identify factors that predict differences in hospital performance. A mixed methods design includes (1) an interrupted time series analysis to evaluate the effect of the intervention on six indicators, (2) key informant interviews with a purposeful sample of directors/managers from up to 20 maternal-newborn care hospitals to explore factors that influence the use of the dashboard, (3) a provincial survey of obstetrical directors/managers from all maternal-newborn hospitals in the province to measure factors that influence the use of the dashboard, and (4) a multivariable generalized linear mixed effects regression analysis of the indicators at each hospital to quantitatively evaluate the change in practice following implementation of the dashboard and to identify factors most predictive of use. Study results will provide essential data to develop knowledge

  16. HIV associated neurocognitive disorders (HAND in Malawian adults and effect on adherence to combination anti-retroviral therapy: a cross sectional study.

    Directory of Open Access Journals (Sweden)

    Christine M Kelly

    Full Text Available Little is known about the prevalence and burden of HIV associated neurocognitive disorder (HAND among patients on combination antiretroviral therapy (cART in sub-Saharan Africa. We estimated the prevalence of HAND in adult Malawians on cART and investigated the relationship between HAND and adherence to cART.HIV positive adults in Blantyre, Malawi underwent a full medical history, neurocognitive test battery, depression score, Karnofsky Performance Score and adherence assessment. The Frascati criteria were used to diagnose HAND and the Global Deficit Score (GDS was also assessed. Blood was drawn for CD4 count and plasma nevirapine and efavirenz concentrations. HIV negative adults were recruited from the HIV testing clinic to provide normative scores for the neurocognitive battery.One hundred and six HIV positive patients, with median (range age 39 (18-71 years, 73% female and median (range CD4 count 323.5 (68-1039 cells/µl were studied. Symptomatic neurocognitive impairment was present in 15% (12% mild neurocognitive disorder [MND], 3% HIV associated dementia [HAD]. A further 55% fulfilled Frascati criteria for asymptomatic neurocognitive impairment (ANI; however factors other than neurocognitive impairment could have confounded this estimate. Neither the symptomatic (MND and HAD nor asymptomatic (ANI forms of HAND were associated with subtherapeutic nevirapine/efavirenz concentrations, adjusted odds ratio 1.44 (CI. 0.234, 8.798; p = 0.696 and aOR 0.577 (CI. 0.09, 3.605; p = 0.556 respectively. All patients with subtherapeutic nevirapine/efavirenz levels had a GDS of less than 0.6, consistent with normal neurocognition.Fifteen percent of adult Malawians on cART had a diagnosis of MND or HAD. Subtherapeutic drug concentrations were found exclusively in patients with normal neurocognitive function suggesting HAND did not affect cART adherence. Further study of HAND requires more robust locally derived normative neurocognitive values and

  17. Pedigree with frontotemporal lobar degeneration – motor neuron disease and Tar DNA binding protein-43 positive neuropathology: genetic linkage to chromosome 9

    Directory of Open Access Journals (Sweden)

    Loy Clement T

    2008-08-01

    Full Text Available Abstract Background Frontotemporal lobar degeneration (FTLD represents a clinically, pathologically and genetically heterogenous neurodegenerative disorder, often complicated by neurological signs such as motor neuron-related limb weakness, spasticity and paralysis, parkinsonism and gait disturbances. Linkage to chromosome 9p had been reported for pedigrees with the neurodegenerative disorder, frontotemporal lobar degeneration (FTLD and motor neuron disease (MND. The objective in this study is to identify the genetic locus in a multi-generational Australian family with FTLD-MND. Methods Clinical review and standard neuropathological analysis of brain sections from affected pedigree members. Genome-wide scan using microsatellite markers and single nucleotide polymorphism fine mapping. Examination of candidate genes by direct DNA sequencing. Results Neuropathological examination revealed cytoplasmic deposition of the TDP-43 protein in three affected individuals. Moreover, we identify a family member with clinical Alzheimer's disease, and FTLD-Ubiquitin neuropathology. Genetic linkage and haplotype analyses, defined a critical region between markers D9S169 and D9S1845 on chromosome 9p21. Screening of all candidate genes within this region did not reveal any novel genetic alterations that co-segregate with disease haplotype, suggesting that one individual carrying a meiotic recombination may represent a phenocopy. Re-analysis of linkage data using the new affection status revealed a maximal two-point LOD score of 3.24 and a multipoint LOD score of 3.41 at marker D9S1817. This provides the highest reported LOD scores from a single FTLD-MND pedigree. Conclusion Our reported increase in the minimal disease region should inform other researchers that the chromosome 9 locus may be more telomeric than predicted by published recombination boundaries. Moreover, the existence of a family member with clinical Alzheimer's disease, and who shares the disease

  18. Effects of regular physical activity on anthropometric and functional parameters in young and old women

    Directory of Open Access Journals (Sweden)

    Sebastião Gobbi

    2001-12-01

    Full Text Available The aim of the present study was to verify the strength levels and the arm cross-sectional-area (AMB of young and old women who practice physical activity regularly. Thirty female subjects were selected and distributed into two groups: young (G1 and old (G2. They were evaluated on maximal voluntary strength of elbow flexor muscle by 1RM (one-maximal repetition test (“biceps curl”, and the AMB, through the measures of arm circumference (CB and triceps skinfold (DCTr, which were then used with the equation proposed by Frisancho (1984: AMB (cm2 = [(CB - pDCTr2 / 4p] - 6.5, in both dominant (MD and non dominant (MND arms. Strength (kg and AMB (cm2 were analyzed by ANOVA to a significance level of 5%. The G2 strength level was significantly (p RESUMO O presente estudo teve como objetivo verificar os níveis de força e a área muscular do braço (AMB de mulheres jovens e idosas praticantes de atividade física regular. Para isso foram selecionados 30 sujeitos do sexo feminino, distribuídos em dois grupos: jovem (G1 e idoso (G2. Avaliou-se a força voluntária máxima dos músculos flexores do cotovelo pelo teste de 1RM (repetição máxima exercício “rosca unilateral” , e a AMB, através das medidas de circunferência de braço (CB e dobra cutânea tricipital (DCTr, que posteriormente foram incluídas na equação proposta por Frisancho (1984: AMB (cm = [(CB - pDCTr2 / 4p] - 6.5, em ambos os membros dominante (MD e não dominante (MND. Os valores de força (em kg e AMB (em cm2 foram analisados por ANOVA com nível de significância pré-estabelecido em 5%. O nível de força do G2 foi significativamente (p<0,01 menor que G1, tanto no MD quanto no MND. Em relação à AMB, o MND de G2 mostrou-se maior que G1, o que não ocorreu com o MD. A partir da análise dos resultados, concluiu-se que apesar do envelhecimento, a prática regular de atividade física pode prevenir a perda de massa muscular (MM. Contudo, a capacidade para gerar for

  19. Põnevat Saaremaa Muuseumis : (Kuressaare linnuses)

    Index Scriptorium Estoniae

    2002-01-01

    Kati Haarakalju ruunimärkidega objektide näitus "Hing" 18. VI-15. VII. Rootsi Riikliku Ajaloomuuseumi rändnäitus "Viikingid idakaares" 8. V-30. VI. Rõivad Narva Muuseumi ajalooliste kostüümide teatri kollektsioonist, Fideelia maalid 7.-28. VII. Ago Ruusi fotonäitus "Mina ja sina" 30. juunini. Eduard Tüüri karikatuurid "Tervislikud jamad" 1.-28. VII. Hans Fjällströmi puust intarsiatehnikas pildid Põhja-Rootsist 11. VI-6. VII. Ehalill Halliste gobelään "Valge valgus" ja Ene Parsi lapitööd 5.-30 VI. Tiina Tammetalu maalid 3.-28. VII

  20. ESL aastapreemia 2006 žürii koosoleku protokoll : 4. aprill 2007 = ESL annual prize 2006 official minutes of the meeting of the jury : April 4th 2007

    Index Scriptorium Estoniae

    2007-01-01

    2006. a. ühiskondliku interjööri preemia Hannelore Pihlakule ja Kristi Lentsile Viimsi koolimaja interjööride eest, ajaloolise interjööri preemia Lembit Andres Torgile firma Koger & Partnerid kontori interjööride eest Fahle majas, näitusekujunduse preemia Mari Kurismaale ja Mari Kaljustele Kumu Kunstimuuseumis eksponeeritud Felicie Ropsi loomingu näituse "Eros ja Surm" kujunduse ja graafilise kujunduse eest, büroo interjööri preemia Taavi Aunrele Velvet Creative Alliance bürooruumide interjööride eest, esemepreemia Tiina Mangile diivanikomplekti Black eest. Žürii koosseis lk. 8

  1. The I-tese Letter - Number 16 Summer 2012. Itese Days 2010

    International Nuclear Information System (INIS)

    Behar, Christophe; Bigot, Bernard; Bennouna, Samia; Dautremont, Severine; Devezeaux, Jean-Guy; Koljonen, Tiina; Legee, Frederic; Percebois, Jacques; Thais, Francoise

    2012-01-01

    This issue contains contributions made during a meeting. The authors addressed the technological perspectives for to-morrow and after-to-morrow energy mixes (Bernard Bigot, CEA), the de-carbonated energy mix for to-morrow (Christophe Behar, CEA), the issue of to-morrow's energy mix (I-tese), methods and criteria to be used for energy prospective studies (Jacques Percebois), the economic impacts of the Fukushima accident (Frederic Legee, Samia Bennouna, Severine Dautremont and Francoise Thais, I-tese), why and how the transition to low carbon energy systems calls for multilevel perspectives and new analysis methodologies (Tiina Koljonen, VTT)

  2. TÜ, TPÜ ja EHI uusi magistreid / Eda Tursk, Hille Roots, Heidi Meier

    Index Scriptorium Estoniae

    Tursk, Eda

    2004-01-01

    Tartu ülikooli eesti ja soome-ugri keeleteaduse osakonnas ning kirjanduse ja rahvaluule osakonnas kaitsesid 2003.a. magistritööd Niina Aasmäe, Piret Voll, Larissa Degel, Reet Hendrikson, Tiina Pai, Petar Kehayov, Anna Baidullina, Katrin Ennus, Kristi Jõesaar, Ell Vahtramäe, Lauri Sommer, Andreas Kalkun, Mirjam Hinrikus, Kristel Nõlvak. Tallinna Pedagoogikaülikoolis kaitsesid 2003.a. magistritööd Sirje Nootre, Merike Mägedi, Tiiu Koovit, Heidi Meier, Jaanika Stackhouse, Lilian Ossi, Annika Vamper, Marika Mikkor, Piret Õunapuu, Helin Puksand, Taimi Rosenberg. Eesti Humanitaarinstituudis kaitses 2003.a. magistritööd Merilin Miljan

  3. Armastan, Sind Eestimaa / Toivo Kallas

    Index Scriptorium Estoniae

    Kallas, Toivo

    2007-01-01

    Laulupidudel esitatud isamaalistest lauludest. Kultuuriselts Hirvepark ja Eesti Kooriühing on ellu kutsunud isamaaliste koorilaulude konkursi, II konkursi võitjad olid Sirje Kaasiku laul "Tahan presidendiks" (I preemia laste- ja poistekooride kategoorias), Riine Pajusaare "Õnnelaul" ja "Lambad on kadunud" (II preemia), Alo Ritsingu "Rivilaul" ja Sirje Kaasiku "Ema nimed" (III preemia); segakooride kategoorias Urmas Sisaski "Eestlastele" ja Tiina Kiilaspea "Tähediamendid" (II preemia), Sirje Kaasik "Armastuse ülemlaul" (III preemia); meeskoorilauludest Alo Ritsingu "Teretus" ja "Kojuigatsus" (III preemia), Erki Meisteri "Roimar" (III preemia), naiskooride kategoorias Alo Ritsingu "Kevad kumiseb" (III preemia). Kontserdist 18. veebr. Estonia kontserdisaalis

  4. Milliseid erialaseid teadmisi ja oskusi olete kasutanud oma praeguses ametis? : vastavad infoteaduse eriala vilistlased / interv. Hela Ojasaar, Margot Mahlapuu

    Index Scriptorium Estoniae

    2005-01-01

    Vastavad: EV Presidendi Kantselei direktori asetäitja, üldosakonna juhataja Riina Roomet, Mahtra Talurahvamuuseumi direktor Tiia-Helle Schmitte, EBS-i raamatukogu juhataja Eda Pihu, Euroopa Liidu asjade komisjoni nõunik (Riigikogu) Külli Kask, Kultuuriministeeriumi raamatukogunõunik Meeli Veskus, Võrumaa Keskraamatukogu direktor Inga Kuljus, Lääne Maakonna Keskraamatukogu direktor Ilme Sepp, Riigiarhiivi direktor Marge Tiidus, kirjastuse Pilgrim juht Tiina Ristimets, Tallinna Keskraamatukogu direktor Kaie Holm, Eesti ENIC/NARIC Keskuse infospetsialist Liia Tüür, Eesti Rahvusraamatukogu direktor Tiiu Valm, Tartu Ülikooli Raamatukogu teenindusdirektor Mare-Nelli Ilus, Viljandi Kultuuriakadeemia raamatukogunduse ja infoteaduste osakonna juhataja Ilmar Vaaro

  5. Electron correlation effects in the half-metallic NiMnSb within a cluster-perturbation approach with ab-initio parameters

    Directory of Open Access Journals (Sweden)

    H. Allmaier

    2008-06-01

    Full Text Available  Using a combination of electronic-structure and many-body calculations, we investigate correlations effects in the halfmetallic ferromagnet NiMnSb. A realistic many-body Hamiltonian, containing only Mn-d orbitals shows the importance of non-quasiparticle states just above the Fermi level. Our results suggest that for a better description of low energy states around Fermi level, Ni-d orbitals should be explicitly included.

  6. Sialorrhoea: How to Manage a Frequent Complication of Motor Neuron Disease

    OpenAIRE

    Andrea Pellegrini; Christian Lunetta; Carlo Ferrarese; Lucio Tremolizzo

    2015-01-01

    Sialorrhoea, the unintentional loss of saliva through the mouth, is the frequent complication of neurological disorders affecting strength or coordination of oropharyngeal muscles, such as motor neuron disease/amyotrophic lateral sclerosis (MND/ALS) or Parkinson’s disease. Sialorrhoea might affect up to 42% of ALS patients, with almost half of them having poorly managed symptoms. Sialorrhoea can impair patients’ social life, while dermatological complications, such as skin rashes, may arise d...

  7. Finding Effective Responses Against Cyber Attacks for Divided Nations

    Science.gov (United States)

    2015-12-01

    Coordination Center LTE Long Term Evolution MAC Media Access Control MCRC Master Control and Reporting Center MEI Ministry of Electronics...satellites that aid Internet connections. Individual users can access the Internet via not only a wired connection up to 1 Gbps, but also by 4G LTE ...operate air-gapped intranets with security measures such as cryptographic modules that correspond to security levels. The MND does maintain the public

  8. Studentõ vidjat Gorholl krasotshnõm / Tiina Rekand

    Index Scriptorium Estoniae

    Rekand, Tiina, 1985-

    2007-01-01

    Tallinna Tehnikakõrgkooli arhitektuuritudengite ideid Tallinna Linnahalli atraktiivsemaks muutmiseks. Juhendas külalisõppejõud Pekingist arhitekt Chi Ti-nan. Kommenteerib tudeng Johanna Jüssi. Õpikojas valminud installatsioone eksponeeriti Linnahalli ümbruses ja nende põhjal loodud fotonäitust näidati Linnahallis ja Linnavalitsuse infosaalis

  9. Rändavad piirid : postkolonialismi võimalused / Tiina Kirss

    Index Scriptorium Estoniae

    Kirss, Tiina, 1957-

    2001-01-01

    Postkolonialism: interdistsiplinaarne uurimissuund, mis tegeleb peamiselt "kolmanda maailma" pärisrahvaste kirjanduste ja kultuuridega. Ka postkolonialismi uurimismeetodite kasutamise võimalustest eesti kirjandusteaduses

  10. Koosolek süvendab ühtekuuluvustunnet / Tiina Kilkson

    Index Scriptorium Estoniae

    Kilkson, Tiina

    2005-01-01

    AS-i Invicta turundusjuht Urmas Pail ja Sideameti klienditeeninduse osakonna juhataja Marge Ensling koosolekute läbiviimisest oma ettevõttes. Lisad: Ajakavast tuleb rangelt kinni pidada; Kõik strateegilised ideed aruta koosolekul läbi; Koosolekule kutsuge vaid asjasse puutuvad inimesed. Vt. ka lk. 15: Karl Multer. Telefonikoosolek aitab hoida töötajate aega kokku. Lisa: Parema tulemuse nimel tuleb valida rahulikum tempo

  11. Pestalozzi programmiga Horvaatias õppimas / Tiina Saamot, Kadri Malin

    Index Scriptorium Estoniae

    Saamot, Tiina

    2010-01-01

    Pestalozzi on Euroopa nõukogu programm, mis pakub koolitust hariduse valdkonnas töötavatele professionaalidele. Zagrebis 17.–20. maini toimunud koolitusest, mille teemaks oli tegevusuuring (action research)

  12. Three Women in Quest of Narrative / Tiina Kirss

    Index Scriptorium Estoniae

    Kirss, Tiina, 1957-

    2008-01-01

    Epp Annuse romaanist "Sina, Matilda" (Tallinn : Tuum, 2007), Kärt Hellermaa novellikogust "Ma armastasin David Copperfieldi" (Tallinn : Tuum, 2007) ja Kristiina Ehini lühiproosakogust "Pillipuhujanaine ja pommipanijanaine" (Tallinn : Huma, 2006)

  13. Üks kordaläinud joonistuskonkurss / Tiina Vapper

    Index Scriptorium Estoniae

    Vapper, Tiina, 1955-

    2014-01-01

    Jäätisetootja Balbiino jäätisepaberi kujundamise konkursist. Lasteaialastel ja põhikooliõpilastel oli võimalus ise välja mõelda „Minu jäätise” jäätisepaber. Konkursi võitis kolmeaastane Pauline Tanis Tallinna Nurmenuku lasteaiast õpetaja Reena Uusmetsa juhendamisel

  14. "Beverly Hills 90210" : kes mida teeb / Tiina Lepiste

    Index Scriptorium Estoniae

    Lepiste, Tiina

    2003-01-01

    Aaron Spellingu produtseeritud ja 2000. aastal lõpetatud menuseriaalis "Beverly Hills 90210" osalenud näitlejate edaspidisest elust seoses plaaniga teha täispikk mängufilm "10 Year High School Reunion"

  15. Rahva lennukirg kindlustas käibe / Tiina Kolk

    Index Scriptorium Estoniae

    Kolk, Tiina

    2003-01-01

    Toitlustusettevõtete TOP 30 2. koht. Lennufirmade reisijaid toitlustav Airo Catering Services Eesti OÜ kuulub osaliselt maailma pardatoitlustust hõlmava LSG Sky Chefs-i kontserni. Ettevõtte pearaamatupidaja Reet Savisikk viitab majandusnäitajate sõltuvusele lennureisijate arvust ning tutvustab pardatoitlustamise põhimõtteid, personali koolitust ja rahvusvahelist koostööd. Kommenteerivad Erki Urva ja Ain Alvela. Vt. samas: Airo Catering Services Eesti OÜ; Näidismenüü Londoni-reisil

  16. Kas pangalaen või kolmas laps? / Tiina Oraste

    Index Scriptorium Estoniae

    Oraste, Tiina

    2007-01-01

    Ilmunud ka:: Järva Teataja, 1. nov. 2007, lk. 2; Sakala, 1. nov. 2007, lk. 2; Valgamaalane, 1. nov. 2007, lk. 2; Lääne Elu, 1. nov. 2007, lk. 2; Vooremaa, 1. nov. 2007, lk. 2; Hiiu Leht, 2. nov. 2007, lk. 2; Harju Ekspress, 2. nov. 2007, lk. 6; Kuulutaja, 2. nov. 2007, lk. 4; Koit, 3. nov. 2007, lk. 6; Oma Saar, 6. nov. 2007, lk. 5; Sõnumitooja, 7. nov. 2007, lk. 2; Vali Uudised, 7. nov. 2007, lk. 2; Türi Rahvaleht, 16. nov. 2007, lk. 4. Autor selgitab majandus- ja kommunikatsiooniminister Juhan Partsi ettepanekut, et riik peaks aitama eluasemelaenu tagasimaksmisel mitmelapselisi perekondi

  17. Eesti arhitektuur trügis maailmakaardile / Tiina Kolk

    Index Scriptorium Estoniae

    Kolk, Tiina

    2004-01-01

    Neli eesti arhitektide projekteeritud hoonet on pääsenud kunstikirjastuse Phaidon raamatusse "The Phaidon Atlas of Contemporary World Architecture": Indrek Allmanni paariselamu Luccas, Martin Aunini eramu Orro Tabasalus, Indrek Näki Neiseri tööstushoone ja büroo 3+1 arhitektide Villa V. 3+1 arhitektid Markus Kaasik, Andres Ojari, Ilmar Valdur ja Inga Raukas esindavad ka Leedumaad Eesti saatkonnahoonega Vilniuses. 4 ill

  18. Näitus pakub vaadet eri maailmadesse / Tiina Sarv

    Index Scriptorium Estoniae

    Sarv, Tiina, 1949-

    2006-01-01

    Omapärane rahvusvaheline kunstinäitus Viljandis Kondase keskuses. Psühhiaatrilistele patsientidele tuge pakkuva ühingu Singel juhi Linda Luhse kutsel on oma tööd Viljandisse toonud Kashtshenko-nimelise Peterburi 1. Psühhiaatriahaigla kunstistuudio. Lisaks on väljas Viljandi kunstiharrastajate tööd

  19. Florence Nightingale'i medal / tõlk. Tiina Vilberg

    Index Scriptorium Estoniae

    1999-01-01

    Medal on asutatud 16. mail 1912 inglise halastajaõe Florence Nightingale'i mälestuseks, kelle omakasupüüdmatu töö haavatute eest hoolitsemisel Krimmi sõjas juhtis haigeravi täiesti uutele radadele

  20. Lõunamaa kunstnik imetleb Eesti valgeid pilvi / Tiina Sarv

    Index Scriptorium Estoniae

    Sarv, Tiina, 1949-

    2003-01-01

    Jutuajamine Bakuu teatri YUG peakunstniku, maalija ja karikaturisti Rashid Sherifiga tema elust ja loomingust. Ugala fuajees oli ka tema siidimaalide näitus. Rashid Sherif on Ugalas 20. septembril esietenduva "Dekameroni" kunstnik

  1. Uuenenud linnaruum Kopenhaageni näitel / Tiina Tammer

    Index Scriptorium Estoniae

    Tammer, Tiina, 1960-

    1998-01-01

    Kopenhaageni väljakute ئ Rõdhuspladsen, Gammeltorv/Nytorv, Amagertorv, Otto Maensteds Plads, Jarmers Plads ئ kujundusest. Näitus 'Kopenhaagen ئ järjepidevuse kontseptsioonid' Eesti Arhitektuurimuuseumis Rotermanni soolalaos

  2. Ajamasin kerib tagasi! / Tiina Lokk ; intervjueerinud Jaan Ruus

    Index Scriptorium Estoniae

    Lokk, Tiina, 1955-

    2009-01-01

    13. Pimedate Ööde filmifestivali peakorraldaja eelseisva festivali ava- ja lõpufilmist - ameeriklase Marc Webb'i "(500) päeva armastust" alguseks ja venelase Valeri Todorovski "Moevennad" lõpetamiseks

  3. Eestlased kiidavad Jeltsinit / Kärt Karpa, Tiina Joosu

    Index Scriptorium Estoniae

    Karpa, Kärt, 1973-

    2000-01-01

    Vene presidendi Boriss Jeltsini tõusud ja langused. A. Rüütel, E. Savisaar, A. Aasmäe, J. Kahn kommenteerivad kohtumisi tagasiastunud presidendiga. Vt. samas K. Karpa art. Kallas näeb Putini tõusus õukonna intriigi, kus ka T.H. Ilves, A. Tarand ja S. Kallas kommenteerivad B. Jeltsini tagasiastumist

  4. Divadlo on teater, Nitra on linn / Tiina Talts

    Index Scriptorium Estoniae

    Talts, Tiina

    2006-01-01

    Rahvusvahelisest teatrifestivalist "Divadelna Nitra" ("Teatraalne Nitra") Slovakkias 22. - 27. septembrini. Lühidalt lavastustest Georg Brüchner "Woyzeck" (Wojciech Boguslawski teater, Poola, lavastaja Maja Kleczewska); Thomas Bernhard "Before retirement" (Slovakkia teater Astorka-Korzo'90, lavastaja Juraj Nvota); Tatjana Tolstaja "Sonja" (Läti Riia Uus Teater, lavastaja Alvis Hermanis); Michel Houllebecq "Platform" (Belgia NTGent, lavastaja Johan Simons); William Shakespeare "Richard III" (Tšehhi Rahvusteater, lavastaja Michal Docekal); Neil LaBute "The shape of things" (Slovakkia Andrej Bagari Teater, lavastajad Roman Olekshak ja Maja Hrieshik); Rainald Goetz-Martin Heidegger "The consolation of the country path" (Tšehhi kodanike ühendus Mezery, lavastaja Miroslav Bambushek); Mark Ravenhill "Product" (Inglismaa Paines Plough, lavastaja Ravenhill); Anton Tshehhov "Ivanov" (Slovakkia Kammerteater, lavastaja Roman Polak)

  5. Kolmest Tallinna Ülikooli Humboldti stipendiaadist / Tiina Tamkivi

    Index Scriptorium Estoniae

    Tamkivi, Tiina

    2014-01-01

    Tallinna Ülikooli külastas jaanuaris teadlasi toetava fondi Alexander von Humboldt Stiftung president ja Berliini Tehnikaülikooli keemiaprofessor Helmut Schwarz. Tallinna Ülikoolist on Humboldti stipendiumi pälvinud kolm teadlast - professor Peeter Järvelaid, ajaloolane Juhan Kreem ja kunstiajaloolane Kersti Markus, kes lisavad artiklis ka omapoolsed selgitused

  6. Lutshim dizaineram vrutshenõ premii Bruno / Tiina Kolk

    Index Scriptorium Estoniae

    Kolk, Tiina

    2008-01-01

    26. septembril tehti Arhitektuuri- ja disainigaleriis teatavaks Eesti disainiauhinna Bruno võitjad. Parima tootedisaini preemia sai Mare Kelpman, parima disainiprojekti eest sai preemia Tarmo Luisk ja eeskujuliku design management'i eest sai preemia ByRoller. Rahvusvahelisse žürii koosseis. Kommenteerib Ilona Gurjanova

  7. Kui tegelikkusest on kõrini / Tiina Väljaste

    Index Scriptorium Estoniae

    Väljaste, Tiina, 1964-

    2008-01-01

    Eesti, läti ja leedu nüüdiskunsti näitus Pariisi kunstikeskuses Cité Internationale des Arts. Eesti väljapaneku kuraator on Aili Vahtrapuu. Pikemalt Jüri Ojaveri installatsioonist "Kirves ja kuu", Urmas Viigi graafilis-tekstilisest karusaagast. Nimetatud teisi osalejaid

  8. Sonya Smith ja telenovela-äri / Tiina Lepiste

    Index Scriptorium Estoniae

    Lepiste, Tiina

    2006-01-01

    Telenovelade ärist ja fenomenist. Ka Venetsueela päritolu näitlejannast Sonya Smithist seriaalis "Armastuse jõud". Sama: Teleleht, 17. Jul. 2006, nr. 28, lk. 6-7 : ill pealkirjaga "Seebiäri vohab ja õitseb"

  9. Outcomes of physical therapy, speech pathology, and occupational therapy for people with motor neuron disease: a systematic review.

    Science.gov (United States)

    Morris, Meg E; Perry, Alison; Bilney, Belinda; Curran, Andrea; Dodd, Karen; Wittwer, Joanne E; Dalton, Gregory W

    2006-09-01

    This article describes a systematic review and critical evaluation of the international literature on the effects of physical therapy, speech pathology, and occupational therapy for people with motor neuron disease (PwMND). The results were interpreted using the framework of the International Classification of Functioning, Disability and Health. This enabled us to summarize therapy outcomes at the level of body structure and function, activity limitations, participation restrictions, and quality of life. Databases searched included MEDLINE, PUBMED, CINAHL, PSYCInfo, Data base of Abstracts of Reviews of Effectiveness (DARE), The Physiotherapy Evidence data base (PEDro), Evidence Based Medicine Reviews (EMBASE), the Cochrane database of systematic reviews, and the Cochrane Controlled Trials Register. Evidence was graded according to the Harbour and Miller classification. Most of the evidence was found to be at the level of "clinical opinion" rather than of controlled clinical trials. Several nonrandomized small group and "observational studies" provided low-level evidence to support physical therapy for improving muscle strength and pulmonary function. There was also some evidence to support the effectiveness of speech pathology interventions for dysarthria. The search identified a small number of studies on occupational therapy for PwMND, which were small, noncontrolled pre-post-designs or clinical reports.

  10. New trace element determinations in the fingernails of ALS patients

    Energy Technology Data Exchange (ETDEWEB)

    Van Dalsem, D.J.; Ehmann, W.D. [Univ. of Kentucky, Lexington, KY (United States); Robinson, L. [Oak Ridge National Laboratory, TN (United States)

    1996-12-31

    Amyotrophic lateral sclerosis (ALS) afflicts 2 of every 100,000 people in the United States each year. A well-known example of ALS today is Stephen Hawking. He is a theoretical physicist, the author of A Brief History of Time, and is virtually immobilized by ALS. Diseases that cause progressive paralysis because of motor neuron degeneration in the central nervous system are termed motor neuron disorders (MND). Amyotrophic lateral sclerosis is a common form of MND. Pain-free, progressive muscular weakness is the most common clinical symptom. There is chronic weakness with atrophy of the affected muscles by the time the disease is diagnosed. Atrophy eventually results in wheelchair confinement and then only bed without the ability to speak or swallow. Death often occurs as a result of respiratory problems. Unlike other neurodegenerative diseases, in ALS the patient`s bladder and bowel control, eye movement, and mental faculties are preserved. The question today is whether or not certain trace elements are involved in the etiology or pathogenesis of ALS. A collaborative study was undertaken by the University of Kentucky and Oak Ridge National Laboratory (ORNL) using neutron activation analysis (NAA) to study trace element concentrations in ALS patients fingernails to determine if there existed statistically significant imbalances.

  11. FTLD-TDP with motor neuron disease, visuospatial impairment and a progressive supranuclear palsy-like syndrome: broadening the clinical phenotype of TDP-43 proteinopathies. A report of three cases

    Directory of Open Access Journals (Sweden)

    Holmerová Iva

    2011-05-01

    Full Text Available Abstract Background Frontotemporal lobar degeneration with ubiquitin and TDP-43 positive neuronal inclusions represents a novel entity (FTLD-TDP that may be associated with motor neuron disease (FTLD-MND; involvement of extrapyramidal and other systems has also been reported. Case presentation We present three cases with similar clinical symptoms, including Parkinsonism, supranuclear gaze palsy, visuospatial impairment and a behavioral variant of frontotemporal dementia, associated with either clinically possible or definite MND. Neuropathological examination revealed hallmarks of FTLD-TDP with major involvement of subcortical and, in particular, mesencephalic structures. These cases differed in onset and progression of clinical manifestations as well as distribution of histopathological changes in the brain and spinal cord. Two cases were sporadic, whereas the third case had a pathological variation in the progranulin gene 102 delC. Conclusions Association of a "progressive supranuclear palsy-like" syndrome with marked visuospatial impairment, motor neuron disease and early behavioral disturbances may represent a clinically distinct phenotype of FTLD-TDP. Our observations further support the concept that TDP-43 proteinopathies represent a spectrum of disorders, where preferential localization of pathogenetic inclusions and neuronal cell loss defines clinical phenotypes ranging from frontotemporal dementia with or without motor neuron disease, to corticobasal syndrome and to a progressive supranuclear palsy-like syndrome.

  12. Adult-onset Alexander disease, associated with a mutation in an alternative GFAP transcript, may be phenotypically modulated by a non-neutral HDAC6 variant.

    Science.gov (United States)

    Melchionda, Laura; Fang, Mingyan; Wang, Hairong; Fugnanesi, Valeria; Morbin, Michela; Liu, Xuanzhu; Li, Wenyan; Ceccherini, Isabella; Farina, Laura; Savoiardo, Mario; D'Adamo, Pio; Zhang, Jianguo; Costa, Alfredo; Ravaglia, Sabrina; Ghezzi, Daniele; Zeviani, Massimo

    2013-05-01

    We studied a family including two half-siblings, sharing the same mother, affected by slowly progressive, adult-onset neurological syndromes. In spite of the diversity of the clinical features, characterized by a mild movement disorder with cognitive impairment in the elder patient, and severe motor-neuron disease (MND) in her half-brother, the brain Magnetic Resonance Imaging (MRI) features were compatible with adult-onset Alexander's disease (AOAD), suggesting different expression of the same, genetically determined, condition. Since mutations in the alpha isoform of glial fibrillary acidic protein, GFAP-α, the only cause so far known of AOAD, were excluded, we applied exome Next Generation Sequencing (NGS) to identify gene variants, which were then functionally validated by molecular characterization of recombinant and patient-derived cells. Exome-NGS revealed a mutation in a previously neglected GFAP isoform, GFAP-ϵ, which disrupts the GFAP-associated filamentous cytoskeletal meshwork of astrocytoma cells. To shed light on the different clinical features in the two patients, we sought for variants in other genes. The male patient had a mutation, absent in his half-sister, in X-linked histone deacetylase 6, a candidate MND susceptibility gene. Exome-NGS is an unbiased approach that not only helps identify new disease genes, but may also contribute to elucidate phenotypic expression.

  13. Predictors of activity and participation across neurodegenerative conditions: a comparison of people with motor neurone disease, multiple sclerosis and Parkinson's disease.

    Science.gov (United States)

    Morley, David; Dummett, Sarah; Kelly, Laura; Fitzpatrick, Ray; Jenkinson, Crispin

    2018-02-17

    Comparisons between neurological conditions have the potential to inform service providers by identifying particular areas of difficulty experienced by affected individuals. This study aimed to identify predictors of activity and participation in people with motor neurone disease (MND), people with multiple sclerosis (MS) and people with Parkinson's Disease (PD). The Oxford Participation and Activities Questionnaire (Ox-PAQ) and Medical Outcomes Study 36-Item Short Form Survey (MOS SF-36) were administered by postal survey to 386 people with a confirmed diagnosis of MND, MS or PD. Data analyses focused on stepwise regression analyses in order to identify predictors of activity and participation in the three conditions assessed. Three hundred and thirty four participants completed the survey, a response rate of 86.5%. Regression analyses identified multiple predictors of activity and participation dependent on Ox-PAQ domain and disease group, the most prominent being social and physical functioning as measured by the MOS SF-36. Results indicate that the physical and social consequences of neurological illness are of greatest relevance to people experiencing the conditions assessed. Whilst the largely inevitable physical implications of disease take hold, emphasis should be placed on the avoidance of social withdrawal and isolation, and the maintenance of social engagement should become a significant priority.

  14. Systematic review of non-invasive positive pressure ventilation for chronic respiratory failure.

    Science.gov (United States)

    Hannan, Liam M; Dominelli, Giulio S; Chen, Yi-Wen; Darlene Reid, W; Road, Jeremy

    2014-02-01

    This systematic review examined the effect of non-invasive positive pressure ventilation (NIPPV) on patient reported outcomes (PROs) and survival for individuals with or at risk of chronic respiratory failure (CRF). Randomised controlled trials (RCTs) and prospective non-randomised studies in those treated with NIPPV for CRF were identified from electronic databases, reference lists and grey literature. Diagnostic groups included in the review were amyotrophic lateral sclerosis/motor neuron disease (ALS/MND), Duchenne muscular dystrophy (DMD), restrictive thoracic disease (RTD) and obesity hypoventilation syndrome (OHS). Eighteen studies were included and overall study quality was weak. Those with ALS/MND had improved somnolence and fatigue as well as prolonged survival with NIPPV. For OHS, improvements in somnolence and fatigue, dyspnoea and sleep quality were demonstrated, while for RTD, measures of dyspnoea, sleep quality, physical function and health, mental and emotional health and social function improved. There was insufficient evidence to form conclusions regarding the effect of NIPPV for those with DMD. This review has demonstrated that NIPPV influences PROs differently depending on the underlying cause of CRF. These findings may provide assistance to patients and clinicians to determine the relative costs and benefits of NIPPV therapy and also highlight areas in need of further research. Copyright © 2013 Elsevier Ltd. All rights reserved.

  15. iPSC-Based Models to Unravel Key Pathogenetic Processes Underlying Motor Neuron Disease Development

    Directory of Open Access Journals (Sweden)

    Irene Faravelli

    2014-10-01

    Full Text Available Motor neuron diseases (MNDs are neuromuscular disorders affecting rather exclusively upper motor neurons (UMNs and/or lower motor neurons (LMNs. The clinical phenotype is characterized by muscular weakness and atrophy leading to paralysis and almost invariably death due to respiratory failure. Adult MNDs include sporadic and familial amyotrophic lateral sclerosis (sALS-fALS, while the most common infantile MND is represented by spinal muscular atrophy (SMA. No effective treatment is ccurrently available for MNDs, as for the vast majority of neurodegenerative disorders, and cures are limited to supportive care and symptom relief. The lack of a deep understanding of MND pathogenesis accounts for the difficulties in finding a cure, together with the scarcity of reliable in vitro models. Recent progresses in stem cell field, in particular in the generation of induced Pluripotent Stem Cells (iPSCs has made possible for the first time obtaining substantial amounts of human cells to recapitulate in vitro some of the key pathogenetic processes underlying MNDs. In the present review, recently published studies involving the use of iPSCs to unravel aspects of ALS and SMA pathogenesis are discussed with an overview of their implications in the process of finding a cure for these still orphan disorders.

  16. Chemical Genetic Screens for TDP-43 Modifiers and ALS Drug Discovery

    Science.gov (United States)

    2015-03-01

    Champagne , and Pierre Drapeau. 25th international symposium on ALS/MND (5-7 December 2014) Patten SA, Vaccaro A, Drapeau P, Kabashi E, Parker JA...transgenic mice produced with TDP- 43 genomic fragments. Brain 134, 2610-2626 (2011). 6 Kabashi, E., Champagne , N., Brustein, E. & Drapeau, P. In the...swim of things: recent insights to neurogenetic disorders from zebrafish. Trends Genet 26, 373-381 (2010). 7 Kabashi, E., Brustein, E., Champagne , N

  17. Correlations of volcanic ash texture with explosion earthquakes from vulcanian eruptions at Sakurajima volcano, Japan

    Science.gov (United States)

    Miwa, T.; Toramaru, A.; Iguchi, M.

    2009-07-01

    We compare the texture of volcanic ash with the maximum amplitude of explosion earthquakes ( Aeq) for vulcanian eruptions from Sakurajima volcano. We analyze the volcanic ash emitted by 17 vulcanian eruptions from 1974 to 1987. Using a stereoscopic microscope, we classify the glassy particles into smooth surface particles (S-type particles) and non-smooth surface particles (NS-type particles) according to their surface conditions—gloss or non-gloss appearance—as an indicator of the freshness of the particles. S-type particles are further classified into V-type particles (those including vesicles) and NV-type particles (those without vesicles) by means of examinations under a polarized microscopic of polished thin sections. Cross-correlated examinations against seismological data show that: 1) the number fraction of S-type particles (S-fraction) has a positive correlation with Aeq, 2) the number ratio of NV-type particles to V-type particles (the N/V number ratio) has a positive correlation with Aeq, and 3) for explosions accompanied with BL-type earthquake swarms, the N/V number ratio has a negative correlation with the duration of the BL-Swarms. BL-Swarms refer to the phenomenon of numerous BL-type earthquakes occurring within a few days, prior to an increase in explosive activity [Kamo, K., 1978. Some phenomena before the summit crater eruptions at Sakura-zima volcano. Bull. Volcanol. Soc. Japan., 23, 53-64]. The positive correlation between the N/V number ratio and Aeq could indicate that a large amount of separated gas from fresh magma results in a large Aeq. Plagioclase microlite textual analysis of NV-type particles from five explosive events without BL-Swarms shows that the plagioclase microlite number density (MND) and the L/ W (length/width) ratio have a positive correlation with Aeq. A comparison between textural data (MND, L/ W ratio, crystallinity) and the result of a decompression-induced crystallization experiment [Couch, S., Sparks, R

  18. Medida da velocidade de condução nervosa motora em praticantes de três diferentes modalidades esportivas

    Directory of Open Access Journals (Sweden)

    Luís Paulo Nogueira Cabral Borges

    2013-10-01

    Full Text Available INTRODUÇÃO: Estudos da condução nervosa têm sido focados para o público em geral, porém não para atletas, havendo carência de informações sobre medidas da velocidade de condução nervosa motora (VCNM em indivíduos treinados, especialmente quando diferentes esportes são comparados. OBJETIVO: Medir a VCNM do nervo mediano e fibular comum, em três grupos de modalidades esportivas. Métodos: Foram analisados: um grupo de meio-fundistas (Gmf, n = 6, um grupo de velocistas (Gvel, n = 4 e um grupo de jogadores de handebol (Ghan, n = 5 e comparados com um grupo controle (Gcon, n = 9. Cada voluntário foi submetido a um único exame, no qual foram obtidos os dados para calcular a VCNM dos membros inferiores do Gmf e do Gvel, dos membros superiores do Ghan, e membros superiores e inferiores do Gcon. Os dados da pesquisa apresentaram distribuição normal e variâncias homogêneas, assim, utilizamos o teste t de Student para amostras independentes na comparação das médias da VCNM dos grupos de atletas com as do Gcon e as do Gvel com as do Gmf (comparações intergrupo. O teste t pareado foi usado para comparar as médias da VCNM entre membro dominante (Md e membro não dominante (Mnd (comparações intragrupo. RESULTADOS: Na análise intergrupo foram encontradas diferenças significativas nas comparações entre o Gvel e o Gcon e entre o Gmf e o Gcon (diferença apenas nas comparações entre os Md's. Por outro lado, a análise intragrupo, exibiu diferença significativa apenas nas comparações entre Md e Mnd do Ghan. CONCLUSÃO: O estudo sugere que a VCNM é beneficiada pelo esforço físico, principalmente em esportes com uso predominante dos membros inferiores, e que a maior utilização de um membro superior sobre outro pode levar a diferença significativa nos valores da VCNM do Md e Mnd.

  19. Multidecadal trends in the nesting phenology of Pacific and Atlantic leatherback turtles are associated with population demography

    OpenAIRE

    Robinson, Nathan J.; Valentine, Sara E.; Santidrián Tomillo, Pilar; Saba, Vincent S.; Spotila, James R.; Paladino, Frank V.

    2013-01-01

    Knowledge of the mechanisms influencing phenology can provide insights into the adaptability of species to climate change. Here, we investigated the factors influencing multidecadal trends in the nesting phenology of the leatherback turtle Dermochelys coriacea at Playa Grande, Costa Rica, in the eastern Pacific Ocean and at Sandy Point, US Virgin Islands, in the western Atlantic Ocean. Between 1993 and 2013, the median nesting date (MND) at Playa Grande occurred later, at a rate of ~0.3 d yr-...

  20. United States Air Force Statistical Digest, Fiscal Year 1976 and Transition Quarter (TQ). 31st Edition

    Science.gov (United States)

    1977-04-30

    JMM JMP JPB JlO J11 KBD KBK KCF KCG KCK KCM KCQ KDB KDC KDF KDM KDQ KDR KEA KEB KEC KFB KFC KFS KFU KGL KGM KGN KGX KHD KND LBM LED MBK ITEM DESCRIPTION...KDF KD1’! KDQ KDR KEA KEB KEC KFC KFS KFU KGL KGM KGN KGX KHO KND LBI’ LED MBK MBN 1’!CE MCF MOB MEA MEB MEC MGX MND RBC RED SFJ SFK YFB 474 475 490