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Sample records for mini implant system

  1. Systemic levels of metallic ions released from orthodontic mini-implants.

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    de Morais, Liliane Siqueira; Serra, Glaucio Guimarães; Albuquerque Palermo, Elisabete Fernandes; Andrade, Leonardo Rodrigues; Müller, Carlos Alberto; Meyers, Marc André; Elias, Carlos Nelson

    2009-04-01

    Orthodontic mini-implants are a potential source of metallic ions to the human body because of the corrosion of titanium (Ti) alloy in body fluids. The purpose of this study was to gauge the concentration of Ti, aluminum (Al), and vanadium (V), as a function of time, in the kidneys, livers, and lungs of rabbits that had Ti-6Al-4V alloy orthodontic mini-implants placed in their tibia. Twenty-three New Zealand rabbits were randomly divided into 4 groups: control, 1 week, 4 weeks, and 12 weeks. Four orthodontic mini-implants were placed in the left proximal tibia of 18 rabbits. Five control rabbits had no orthodontic mini-implants. After 1, 4, and 12 weeks, the rabbits were killed, and the selected tissues were extracted and prepared for analysis by graphite furnace atomic absorption spectrophotometry. Low amounts of Ti, Al, and V were detectable in the 1-week, 4-weeks, and 12-weeks groups, confirming that release of these metals from the mini-implants occurs, with diffusion and accumulation in remote organs. Despite the tendency of ion release when using the Ti alloy as orthodontic mini-implants, the amounts of metals detected were significantly below the average intake of these elements through food and drink and did not reach toxic concentrations.

  2. A Mini-review on the Effect of Mini-implants on Contemporary Orthodontic Science.

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    Nosouhian, Saeid; Rismanchian, Mansour; Sabzian, Roya; Shadmehr, Elham; Badrian, Hamid; Davoudi, Amin

    2015-01-01

    The purpose of this literature review was to screen the valuable published articles regarding to the impacts of mini-implants on orthodontic science, briefly. The searching category was performed on the Pubmed using MeSH words such as "dental (mini) implants, orthodontic anchorage procedures, and orthodontic appliances." After preliminary sketch, they were grouped as follow: Those evaluating (a) common appliances for providing orthodontic anchorage, (b) biomechanical details of mini-implants and their insertion, (c) clinical application of mini-implants for orthognathic treatments, (d) limitations and possible complications. In conclusion, mini-implant evolved the orthodontic treatment plans and compromised the required orthognathic surgery. Malocclusion treatment and pure orthodontic or orthopedic movements in the three-dimensions have become recently possible by using mini-implant to provide skeletal anchorage.

  3. Why are mini-implants lost: The value of the implantation technique!

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    Romano, Fabio Lourenço; Consolaro, Alberto

    2015-01-01

    The use of mini-implants have made a major contribution to orthodontic treatment. Demand has aroused scientific curiosity about implant placement procedures and techniques. However, the reasons for instability have not yet been made totally clear. The aim of this article is to establish a relationship between implant placement technique and mini-implant success rates by means of examining the following hypotheses: 1) Sites of poor alveolar bone and little space between roots lead to inadequate implant placement; 2) Different sites require mini-implants of different sizes! Implant size should respect alveolar bone diameter; 3) Properly determining mini-implant placement site provides ease for implant placement and contributes to stability; 4) The more precise the lancing procedures, the better the implant placement technique; 5) Self-drilling does not mean higher pressures; 6) Knowing where implant placement should end decreases the risk of complications and mini-implant loss. PMID:25741821

  4. Paradigm shifts in orthodontic treatment with mini-implant anchorage

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    Johnny Joung-Lin Liaw

    2015-01-01

    Full Text Available After the applications of mini-implant anchorage, the envelope of orthodontic treatment was expanded and some treatment modes were changed because of more predictable tooth movement with empowered anchorage. The author tried to share his experience of TADs applications for clarifying the paradigm shifts of orthodontic treatment assisted with the mini-implant anchorage.

  5. Intrusão dentária utilizando mini-implantes Orthodontic intrusion with mini-implant anchorage

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    Telma Martins de Araújo

    2008-10-01

    Full Text Available INTRODUÇÃO: dentre os diversos tipos de movimentos dentários induzidos ortodonticamente, o de intrusão é, sem dúvida, um dos mais difíceis de serem conseguidos. A mecânica intrusiva convencional, apesar de viável, é complexa, no que diz respeito ao controle de seus efeitos colaterais. Isso, em grande parte, refere-se à dificuldade em se obter uma ancoragem satisfatória. Neste contexto, os mini-implantes, por oferecerem efetiva ancoragem esquelética, têm se mostrado de extrema valia para os ortodontistas, tornando a intrusão, tanto de dentes anteriores quanto posteriores, um procedimento cada vez mais simples, do ponto de vista mecânico. OBJETIVO: pretende-se, então, neste artigo, descrever e demonstrar, clinicamente, as diversas possibilidades de utilização dos mini-implantes como recurso de ancoragem para o movimento de intrusão.INTRODUCTION: Among all different varieties of orthodontically induced tooth movement, intrusion is, without doubt, one of the most difficult movements to be reached. Conventional intrusive biomechanics, although possible, may lead to undesirable side-effects. These events, in most cases, are related to the difficulty in obtaining an efficient anchorage unit. Then, mini-implants, because of their high success rates of effective skeletal anchorage, are valuable devices to orthodontists, transforming the intrusion movement, both at the anterior and the posterior regions, a more and more uncomplicated biomechanical procedure. AIM: to describe and show, clinically, different ways of using mini-implants as an anchorage system to intrusion movement.

  6. Restoration of congenitally missing maxillary lateral incisors using mini implants.

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    Collins, Ron

    2013-11-01

    In this author's opinion, the advent of mini implants, or small diameter implants (SDIs) as they are more frequently being called, is becoming in many situations a viable alternative to the more traditional root form implants. They offer advantages of less cost, a more simplified placement technique, usually faster healing times, and generally less post-operative complications. A case presentation is given to demonstrate their usage for a narrow ridge application to restore congenitally missing maxillary lateral incisors.

  7. Mini-Implants, Mega Solutions: A Case Series.

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    Kumari, Pooja; Verma, Mahesh; Sainia, Vikrant; Gupta, Ankur; Gupta, Rekha; Gill, Shubhra

    2016-12-01

    Dental implants have evolved as a standard of care for replacement of missing teeth. Though this treatment modality promises a high level of patient satisfaction and success, it cannot be performed in all cases. Apart from medically compromised patients, implant use is also restricted whenever there is limited available bone volume at the edentulous site. An example includes the mandibular incisor, the maxillary lateral incisor region, and other sites with reduced interdental spacing and atrophic edentulous maxillary and mandibular ridges. Bone volume at some of these sites can be increased by suitable augmentation procedure for placement of a regular diameter implant (3.75 to 4.2 mm). But many a times such procedure cannot be undertaken either due to financial constraint, risk of subjecting the patient to additional surgical procedure, added time factor, or guarded prognosis of the grafted site. In such cases, mini-implants can be used. In this case series, mini-implants (2.5 to 3 mm) were used to replace teeth in all mouth quadrants and to retain a mandibular overdenture in a compromised case. The implants served well at all the sites with minimal bone loss and a high level of patient satisfaction. Mini-implants hold the potential to serve as an alternate to regular diameter implants in certain situations. Preferably they should be used in multiples to retain fixed dental prostheses and might serve as an efficient, low-cost solution for retaining overdentures in selected cases.

  8. Distalization of maxillary molars using a lever arm and mini-implant.

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    Gurgel, Júlio de Araújo; Pinzan-Vercelino, Célia Regina Maio; Bramante, Fausto Silva; Rivera, Alan Poy

    2013-01-01

    This article describes the orthodontic treatment of a young woman with a Class II malocclusion and maxillomandibular prognathism. One orthodontic mini- implant was placed in the posterior area of the palate to provide anchorage for?a transpalatal arch. The force for molar distalization was applied using an elastic chain from the lever arm inserted on the transpalatal arch to the mini-implant. Two sliding jigs were applied buccally as a complement for Class II malocclusion correction. This system created an efficient mechanotherapy for maxillary molar distalization. The active treatment period was 19 months. Normal overjet and reduction of maxillomandibular prognathism were obtained, and labial balance was improved.

  9. Evaluation of Stability of Surface-Treated Mini-Implants in Diabetic Rabbits

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    Nam-Hee Oh

    2014-01-01

    Full Text Available Introduction. The purpose of this study was to investigate effects of surface treatment of mini-implants in diabetes-induced rabbits by comparing osseointegration around mini-implants. Methods. Twelve New Zealand white rabbits were divided into two groups (alloxan-induced diabetic group and control group. A total of 48 mini-implants were placed after four weeks of diabetic induction. 24 mini-implants were surface-treated with SLA (sandblasted with large grit, and acid etched and the remaining 24 mini-implants had smooth surfaces. Four weeks after placement, 32 mini-implants were removed from 4 control and 4 diabetic rabbits. Insertion and removal torques were measured. The remaining 16 mini-implants from the two groups were histomorphometrically analyzed. Results. Maximum insertion torque showed no difference between diabetic and control groups, but total insertion energy was higher in control group. In surface-treated mini-implants, maximum removal torque was higher in both diabetic and control groups. Bone-implant contact (BIC was increased in the control group when compared to the diabetic group. Surface-treated group had higher BIC than smooth surface group in both control and diabetic groups. However, there was no significantly statistical difference. Conclusions. Type 1 diabetes mellitus and surface treatment method of mini-implant affected primary stability of mini-implants. In addition, the use of orthodontic mini-implants in a diabetic patient is likely to show results similar to the healthy patient.

  10. Nanostructured severe plastic deformation processed titanium for orthodontic mini-implants.

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    Serra, Glaucio; Morais, Liliane; Elias, Carlos Nelson; Semenova, Irina P; Valiev, Ruslan; Salimgareeva, Gulnaz; Pithon, Matheus; Lacerda, Rogério

    2013-10-01

    Titanium mini-implants have been successfully used as anchorage devices in Orthodontics. Commercially pure titanium (cpTi) was recently replaced by Ti-6Al-4V alloy as the mini-implant material base due to the higher strength properties of the alloy. However, the lower corrosion resistance and the lower biocompatibility have been lowering the success rate of Ti-6Al-4V mini-implants. Nanostructured titanium (nTi) is commercially pure titanium that was nanostructured by a specific technique of severe plastic deformation. It is bioinert, does not contain potentially toxic or allergic additives, and has higher specific strength properties than any other titanium applied in medical implants. The higher strength properties associated to the higher biocompatibility make nTi potentially useful for orthodontic mini-implant applications, theoretically overcoming cpTi and Ti-6Al-4V mini-implants. The purposes of the this work were to process nTi, to mechanically compare cpTi, Ti-6Al-4V, and nTi mini-implants by torque test, and to evaluate both the surface morphology and the fracture surface characteristics of them by SEM. Torque test results showed significant increase in the maximum torque resistance of nTi mini-implants when compared to cpTi mini-implants, and no statistical difference between Ti-6Al-4V and nTi mini-implants. SEM analysis demonstrated smooth surface morphology and transgranular fracture aspect for nTi mini-implants. Since nanostructured titanium mini-implants have mechanical properties comparable to titanium alloy mini-implants, and biocompatibility comparable to commercially pure titanium mini-implants, it is suggestive that nanostructured titanium can replace Ti-6Al-4V alloy as the material base for mini-implants.

  11. Buccal cortical bone thickness on CBCT for mini-implant

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    Goo, Jong Gook; Lim, Sung Hoon; Lee, Byoung Jin; Kim, Jae Duk [School of Dentistry, Chosun University, Gwangju (Korea, Republic of)

    2010-12-15

    Cortical bone thickness is one of the important factor in mini-implant stability. This study was performed to investigate the buccal cortical bone thickness at every interdental area as an aid in planning mini-implant placement. Two-dimensional slices at every interdental area were selected from the cone-beam computed tomography scans of 20 patients in third decade. Buccal cortical bone thickness was measured at 2, 4, and 6 mm levels from the alveolar crest in the interdental bones of posterior regions of both jaws using the plot profile function of Ez3D2009TM (Vatech, Yongin, Korea). The results were analyzed using by Mann-Whitney test. Buccal cortical bone was thicker in the mandible than in the maxilla. The thickness increased with further distance from the alveolar crest in the maxilla and with coming from the posterior to anterior region in the mandible (p?0.01). The maximum CT value showed an increasing tendency with further distance from the alveolar crest and with coming from posterior to anterior region in both jaws. Interdental buccal cortical bone thickness varied in both jaws, however our study showed a distinct tendency. We expect that these results could be helpful for the selection and preparation of mini-implant sites.

  12. Osseointegration of standard and mini dental implants: a histomorphometric comparison.

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    Dhaliwal, Jagjit S; Albuquerque, Rubens F; Murshed, Monzur; Feine, Jocelyne S

    2017-12-01

    Mini dental implants (MDIs) are becoming increasingly popular for rehabilitation of edentulous patients because of their several advantages. However, there is a lack of evidence on the osseointegration potential of the MDIs. The objective of the study was to histomorphometrically evaluate and compare bone apposition on the surface of MDIs and standard implants in a rabbit model. Nine New Zealand white rabbits were used for the study to meet statistical criteria for adequate power. Total 18 3M(™)ESPE(™) MDIs and 18 standard implants (Ankylos(®) Friadent, Dentsply) were inserted randomly into the tibia of rabbits (four implants per rabbit); animals were sacrificed after a 6-week healing period. The specimens were retrieved en bloc and preserved in 10% formaldehyde solution. Specimens were prepared for embedding in a light cure acrylic resin (Technovit 9100). The most central sagittal histological sections (30-40 μm thick) were obtained using a Leica SP 1600 saw microtome. After staining, the Leica DM2000 microscope was used, the images were captured using Olympus DP72 camera and associated software. Bone implant contact (BIC) was measured using Infinity Analyze software. All implants were osseointegrated. Histologic measures show mineralized bone matrix in intimate contact with the implant surface in both groups. The median BIC was 57.5% (IQR 9.0) in the MDI group and 55.0% (IQR 4.5) in the control group (P > 0.05, Mann-Whitney test). There were no statistical differences in osseointegration at 6 weeks between MDIs and standard implants in rabbit tibias. Based on these results, it is concluded that osseointegration of MDIs is similar to that of standard implants.

  13. Caracterização de mini-implantes utilizados na ancoragem ortodôntica Characterization of the mini-implants used to orthodontic anchorage

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    Luciana Rougemont Squeff

    2008-10-01

    Full Text Available INTRODUÇÃO: o diâmetro reduzido do mini-implante, e a decorrente facilidade na sua inserção, minimizam a possibilidade de erro do operador e de contato entre a rosca do mini-implante e a raiz dentária. Entretanto, o risco de fratura da peça aumenta à medida que seu diâmetro é diminuído. MÉTODOS: neste trabalho foram analisados quatro produtos de marcas nacionais (INP, SIN, Conexão e Neodente e um de marca alemã (Mondeal, com o objetivo de identificar características importantes para o bom desempenho deste recurso como acessório de ancoragem. Foram observados composição e design das peças e realizado o ensaio mecânico de torque até a fratura (estudo in vitro, cujos valores foram submetidos à análise de variância (ANOVA e teste de Tukey. RESULTADOS: os resultados mostraram que todos os mini-implantes testados estão aptos à utilização clínica como reforço de ancoragem ortodôntica.INTRODUCTION: The reduced diameter of the mini-implants and the simplicity of the technique could minimize the operator mistake's possibility and avoid the contact between the thread of the screw and the dental root. In spite of that, it increases the fracture risk because of the diameter's decrease. METHODS: At the present work, mini-implants from five different trade marks, four Brazilian systems (INP, SIN, Conexão and Neodente and a German system (Mondeal were studied to identify important characteristics of this anchorage accessory, like composition, design and resistance to the insertion torque (in vitro. The values obtained from the mechanical torque test were submitted to variance analysis (ANOVA and Tukey's test. RESULTS: All studied groups presented good results and are recommended to orthodontic clinic use.

  14. Pullout strengths of orthodontic palatal mini-implants tested in vitro

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    Ju-Hui Wu

    2011-12-01

    Conclusion: The pullout strengths of mini-implants were significantly greater than normal orthodontic forces. Moreover, no significant correlation was found between the insertion torque and pullout strength.

  15. Does the design of mini slings anchoring systems really matter? A biomechanical comparison between Mini Arc™ and Ophira™.

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    Santos-Souza, R; Rodrigues-Palma, P C; Goulart-Fernandes-Dias, F; Teixeira-Siniscalchi, R; Zanettini-Riccetto, C L

    2016-11-01

    Currently, a sling implant is the standard treatment for stress urinary incontinence in women. To be effective, they require an adequate anchoring system. The aim of this study is compare biomechanical features of fixation systems of two mini slings models available on the market (Ophira™ and Mini Arc™) through a tensile test. Anchoring devices of each sling were surgically implanted in abdominal wall of 15 rats divided into three groups of five animals which were arranged according to the date of post implant euthanasia on 7, 14 and 30 days. Abdominal walls of rats were extracted on bloc containing the anchoring system and were submitted to a tensile strength test to measure the maximum load and elongation until device avulsion from the tissue. The results were compared using Student test t and a 5% cut off was considered significant. The Ophira™ mini sling fixation system demanded a greater maximum load and developed a longer stretch for avulsion from the implanted site at all moments evaluated (p value less than 0.05). There were significant differences in fixation patterns of the anchoring systems, which were exclusively related to their designs. The Ophira™ mini sling fixation device provided better fixation to the abdominal wall of rats compared to the Mini Arc™ device, even in the late post implant period. Copyright © 2016 AEU. Publicado por Elsevier España, S.L.U. All rights reserved.

  16. Intrusão dentária utilizando mini-implantes Orthodontic intrusion with mini-implant anchorage

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    Telma Martins de Araújo; Mauro Henrique Andrade Nascimento; Fernanda Catharino Menezes Franco; Marcos Alan Vieira Bittencourt

    2008-01-01

    INTRODUÇÃO: dentre os diversos tipos de movimentos dentários induzidos ortodonticamente, o de intrusão é, sem dúvida, um dos mais difíceis de serem conseguidos. A mecânica intrusiva convencional, apesar de viável, é complexa, no que diz respeito ao controle de seus efeitos colaterais. Isso, em grande parte, refere-se à dificuldade em se obter uma ancoragem satisfatória. Neste contexto, os mini-implantes, por oferecerem efetiva ancoragem esquelética, têm se mostrado de extrema valia para os or...

  17. Comparative Clinical Study of Conventional Dental Implants and Mini Dental Implants for Mandibular Overdentures: A Randomized Clinical Trial.

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    Aunmeungtong, Weerapan; Kumchai, Thongnard; Strietzel, Frank P; Reichart, Peter A; Khongkhunthian, Pathawee

    2017-04-01

    Dental implant-retained overdentures have been chosen as the treatment of choice for complete mandibular removable dentures. Dental implants, such as mini dental implants, and components for retaining overdentures, are commercially available. However, comparative clinical studies comparing mini dental implants and conventional dental implants using different attachment for implant-retained overdentures have not been well documented. To compare the clinical outcomes of using two mini dental implants with Equator(®) attachments, four mini dental implants with Equator attachments, or two conventional dental implants with ball attachments, by means of a randomized clinical trial. Sixty patients received implant-retained mandibular overdentures in the interforaminal region. The patients were divided into three groups. In Groups 1 and 2, two and four mini dental implants, respectively, were placed and immediately loaded by overdentures, using Equator(®) attachments. In Group 3, conventional implants were placed. After osseointegration, the implants were loaded by overdentures, using ball attachments. The study distribution was randomized and double-blinded. Outcome measures included changes in radiological peri-implant bone level from surgery to 12 months postinsertion, prosthodontic complications and patient satisfaction. The cumulative survival rate in the three clinical groups after one year was 100%. There was no significant difference (p dental implants with Equator attachments. However, there was a significant difference in marginal bone loss and patient satisfaction between those receiving mini dental implants with Equator attachments and conventional dental implants with ball attachments. The marginal bone resorption in Group 3 was significantly higher than in Groups 1 and 2 (p dental implants can be immediately used successfully for retaining lower complete dentures, as shown after a 1-year follow up. © 2016 Wiley Periodicals, Inc.

  18. Systematic review of mini-implant displacement under orthodontic loading

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    Manuel Nienkemper; Jörg Handschel; Dieter Drescher

    2014-01-01

    A growing number of studies have reported that mini-implants do not remain in exactly the same position during treatment, although they remain stable. The aim of this review was to collect data regarding primary displacement immediately straight after loading and secondary displacement over time. A systematic review was performed to investigate primary and secondary displacement. The amount and type of displacement were recorded. A total of 27 studies were included. Sixteen in vitro studies or studies using finite element analysis addressed primary displacement, and nine clinical studies and two animal studies addressed secondary displacement. Significant primary displacement was detected (6.4-24.4 mm) for relevant orthodontic forces (0.5-2.5 N). The mean secondary displacement ranged from 0 to 2.7 mm for entire mini-implants. The maximum values for each clinical study ranged from 1.0 to 4.1 mm for the head, 1.0 to 1.5 for the body and 1.0 to 1.92 mm for the tail part. The most frequent type of movement was controlled tipping or bodily movement. Primary displacement did not reach a clinically significant level. However, clinicians can expect relevant secondary displacement in the direction of force. Consequently, decentralized insertion within the inter-radicular space, away from force direction, might be favourable. More evidence is needed to provide quantitative recommendations.

  19. Direct aortic transcatheter valve implantation via mini-thoracotomy using the Medtronic CoreValve.

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    Bruschi, Giuseppe; Botta, Luca; De Marco, Federico; Colombo, Paola; Nonini, Sandra; Klugmann, Silvio; Martinelli, Luigi

    2013-01-01

    Transcatheter aortic valve implantation using the Medtronic CoreValve is a well-established procedure. Although previously carried out only through the common femoral artery, today it is possible to perform the procedure through different arterial alternative access sites. A direct aortic approach through the ascending aorta could be carried out via a right anterior mini-thoracotomy in the second intercostal space. The pericardium is opened to expose the aorta. Two purse-string sutures are then placed on the ascending aorta and a standard retrograde CoreValve implantation is performed with the standard delivery system. Advantages, contraindications, surgical technique and results are discussed.

  20. Finite element analysis of different loading conditions for implant-supported overdentures supported by conventional or mini implants.

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    Solberg, K; Heinemann, F; Pellikaan, P; Keilig, L; Stark, H; Bourauel, C; Hasan, I

    2017-03-10

    The effect of implants' number on overdenture stability and stress distribution in edentulous mandible, implants and overdenture was numerically investigated for implant-supported overdentures. Three models were constructed. Overdentures were connected to implants by means of ball head abutments and rubber ring. In model 1, the overdenture was retained by two conventional implants; in model 2, by four conventional implants; and in model 3, by five mini implants. The overdenture was subjected to a symmetrical load at an angle of 20 degrees to the overdenture at the canine regions and vertically at the first molars. Four different loading conditions with two total forces (120, 300 N) were considered for the numerical analysis. The overdenture displacement was about 2.2 times higher when five mini implants were used rather than four conventional implants. The lowest stress in bone bed was observed with four conventional implants. Stresses in bone were reduced by 61% in model 2 and by 6% in model 3 in comparison to model 1. The highest stress was observed with five mini implants. Stresses in implants were reduced by 76% in model 2 and 89% increased in model 3 compared to model 1. The highest implant displacement was observed with five mini implants. Implant displacements were reduced by 29% in model 2, and increased by 273% in model 3 compared to model 1. Conventional implants proved better stability for overdenture than mini implants. Regardless the type and number of implants, the stress within the bone and implants are below the critical limits.

  1. Reasons for mini-implants failure: choosing installation site should be valued!

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    Alberto Consolaro

    2014-04-01

    Full Text Available Mini-implant loss is often associated with physical and mechanical aspects that result from choosing an inappropriate placement site. It is worth highlighting that: a Interdental alveolar bone crests are flexible and deformable. For this reason, they may not offer the ideal absolute anchorage. The more cervical the structures, the more delicate they are, thus offering less physical support for mini-implant placement; b Alveolar bone crests of triangular shape are more deformable, whereas those of rectangular shape are more flexible; c The bases of the alveolar processes of the maxilla and the mandible are not flexible, for this reason, they are more likely to receive mini-implants; d The more cervical a mini-implant is placed, the higher the risk of loss; the more apical a mini-implant is placed, the better its prognosis will be; e 3D evaluations play a major role in planning the use of mini-implants. Based on the aforementioned considerations, the hypotheses about mini-implant loss are as follows: 1 Deflection of maxillary and mandibular alveolar processes when mini-implants are more cervically placed; 2 Mini-implants placed too near the periodontal ligament, with normal intra-alveolar tooth movement; 3 Low bone density, low thickness and low alveolar bone volume; 4 Low alveolar cortical bone thickness; 5 Excessive pressure inducing trabecular bone microfracture; 6 Sites of higher anatomical weakness in the mandible and the maxilla; 7 Thicker gingival tissue not considered when choosing the mini-implant.

  2. Biomechanics and load resistance of small-diameter and mini dental implants: a review of literature.

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    Hasan, Istabrak; Bourauel, Christoph; Mundt, Torsten; Stark, Helmut; Heinemann, Friedhelm

    2014-02-01

    In recent years, the application of small-diameter and mini dental implants to support removable and fixed prosthesis has dramatically increased. However, the success of these implants under functional biting forces and the reaction of the bone around them need to be analyzed. This review was aimed to present studies that deal with the fatigue life of small-diameter and mini dental implants under normal biting force, and their survival rate. The numerical and experimental studies concluded that an increase in the risk of bone damage or implant failure may be assumed in critical clinical situations and implants with dental implants over 5 years was 98.3-99.4%.

  3. Mini-implantes ortodônticos como auxiliares da fase de retração anterior Orthodontic mini-implants assisting the anterior retraction phase

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    Carlo Marassi; Cesar Marassi

    2008-01-01

    INTRODUÇÃO: os mini-implantes ortodônticos se estabeleceram como um importante método de ancoragem e vêm auxiliando os ortodontistas nas várias etapas do tratamento ortodôntico, eliminando, em grande parte, a necessidade de colaboração dos pacientes e tornando os resultados mais previsíveis. OBJETIVO: este artigo descreve os principais aspectos do uso dos mini-implantes como auxiliares da fase de retração anterior, trazendo considerações sobre suas indicações, quantidade de movimentação dos d...

  4. Mini-implantes ortodônticos como auxiliares da fase de retração anterior Orthodontic mini-implants assisting the anterior retraction phase

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    Carlo Marassi

    2008-10-01

    Full Text Available INTRODUÇÃO: os mini-implantes ortodônticos se estabeleceram como um importante método de ancoragem e vêm auxiliando os ortodontistas nas várias etapas do tratamento ortodôntico, eliminando, em grande parte, a necessidade de colaboração dos pacientes e tornando os resultados mais previsíveis. OBJETIVO: este artigo descreve os principais aspectos do uso dos mini-implantes como auxiliares da fase de retração anterior, trazendo considerações sobre suas indicações, quantidade de movimentação dos dentes anteriores, os vetores de força de retração, o controle vertical, o posicionamento dos mini-implantes, os tipos de apoio na região anterior e a força a ser utilizada. São citados os sítios de instalação mais usados para a retração anterior e abordados fatores que deverão ser controlados durante o fechamento de espaço. Por fim, são citadas algumas considerações clínicas sobre o uso dos mini-implantes nessa importante fase do tratamento ortodôntico.INTRODUCTION: The use of orthodontic mini-implants has settled as an important anchorage method and is aiding the orthodontists in the several stages of the treatment, largely eliminating the need of patients' compliance, and turning the results more predictable. AIM: This article describes the main aspects of the use of mini-implants as auxiliaries on the retraction phase of the anterior teeth, bringing considerations about their indications, amount of movement of the anterior teeth, the vectors of retraction force, the vertical control and evaluation of the incisors vestibulolingual tipping, the positioning of the mini-implants, the support types in the anterior area and the force to be applied. The placement sites best used for the anterior retraction are mentioned, and the factors that should be controlled during the space closure are approached. Lastly, some clinical considerations on the use of mini-implants in such important phase of the orthodontic treatment are

  5. Mini-implants in the palatal slope – a retrospective analysis of implant survival and tissue reaction

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    Ziebura Thomas

    2012-11-01

    Full Text Available Abstract Background To identify insertion procedure and force application related complications in Jet Screw (JS type mini-implants when inserted in the palatal slope. Methods Setting and Sample Population: The Department of Orthodontics, the University Hospital Münster. Forty-one consecutively started patients treated using mini-implants in the palatal slope. In this retrospective study, 66 JS were evaluated. Patient records were used to obtain data on the mode of utilization and complications. Standardized photographs overlayed with a virtual grid served to test the hypothesis that deviations from the recommended insertion site or the type of mechanics applied might be related to complications regarding bleeding, gingival overgrowth or implant failure. Results Two implants (3% were lost, and two implants (3%, both loaded with a laterally directed force, exhibited loosening while still serving for anchorage. Complications that required treatment did not occur, the most severe problem observed being gingival proliferation which was attributable neither to patients’ age nor to applied mechanics or deviations from the ideal implant position. Conclusions The JS mini-implant is reliable for sagittal and vertical movements or anchorage purposes. Laterally directed forces might be unfavorable. The selection of implant length as well as the insertion procedure should account for the possibility of gingival overgrowth.

  6. Effect of Recycling Protocol on Mechanical Strength of Used Mini-Implants

    Directory of Open Access Journals (Sweden)

    Sérgio Estelita

    2014-01-01

    Full Text Available Purpose. This study evaluated the influence of recycling process on the torsional strength of mini-implants. Materials and Methods. Two hundred mini-implants were divided into 4 groups with 50 screws equally distributed in five diameters (1.3 to 1.7 mm: control group (CG: unused mini-implants, G1: mini-implants inserted in pig iliac bone and removed, G2: same protocol of group 1 followed by sonication for cleaning and autoclave sterilization, and G3: same insertion protocol of group 1 followed by sonication for cleaning before and after sandblasting (Al2O3-90 µ and autoclave sterilization. G2 and G3 mini-implants were weighed after recycling process to evaluate weight loss (W. All the screws were broken to determine the fracture torque (FT. The influence of recycling process on FT and W was evaluated by ANOVA, Mann-Whitney, and multiple linear regression analysis. Results. FT was not influenced by recycling protocols even when sandblasting was added. Sandblasting caused weight loss due to abrasive mechanical stripping of screw surface. Screw diameter was the only variable that affected FT. Conclusions. Torsional strengths of screws that underwent the recycling protocols were not changed. Thus, screw diameter choice can be a more critical step to avoid screw fracture than recycling decision.

  7. Stabilization of mandibular complete dentures by four mini implants: Impact on masticatory function.

    Science.gov (United States)

    Batisse, C; Bonnet, G; Bessadet, M; Veyrune, J L; Hennequin, M; Peyron, M A; Nicolas, E

    2016-07-01

    The frequent instability of mandibular removable complete dentures causes an alteration of mastication. An innovative therapeutic strategy involves placing four symphyseal mini implants. This study aimed at assessing the development of masticatory parameters and the impact on quality of life in subjects that underwent this procedure. Eleven edentulous subjects (mean age 72±11 years) with unstable mandibular complete dentures were followed-up before (T0) and two - three months after (T1) mini implant setting. Physiological parameters (number of cycles, duration of sequence and frequency of mastication) during the mastication of food models and the bolus median particle size (d50) of carrot were evaluated at each time. Quality of life was assessed at T0 and T1 using the Global Oral Health Assessment Index (GOHAI). Parametric tests were used to test relationships between mastication, quality of life variations and mini implant setting, and to compare each parameter mean value at times T0 and T1. More subjects were able to chew carrot after setting the mini implants (8 subjects compared to 4 at T0). This improvement was accompanied by changes in kinematic parameters when chewing carrots, soft and hard model food, and by an improvement of their quality of life. However, the particle size values observed in the bolus remained higher than for normal dentate subjects (9.2±2.8mm). These results indicated that the placement of mini implants as retentive elements for mandibular full dentures had a positive impact on patients' masticatory function and quality of life. The placement of mini implants has a positive impact on the masticatory function and oral health quality of life. The results suggest that this alternative procedure can be used as a treatment option for patients unable to receive conventional implants. Copyright © 2016 Elsevier Ltd. All rights reserved.

  8. [Mini-implants: pushing the limits of traditional orthodontics].

    Science.gov (United States)

    Ellouze, Skander

    2008-03-01

    With the introduction during the last years of new tools such as low friction braces, skeletal anchorage, and especially mini screws, the tremendous evolution of lingual orthodontics, orthodontic care has evolved at a rhythm never known before. Using various clinical examples, the author shows the tremendous impact of the use of mini screws in a great number of treatments, producing particularly favourable facial changes, often going beyond the usual limits of orthodontic treatments.

  9. Use of Orthodontic Mini-Implants for Maxillomandibular Fixation in Mandibular Fracture

    Science.gov (United States)

    Pires, Mario Sergio Medeiros; Reinhardt, Leandro Calcagno; Antonello, Guilherme de Marco; Torres do Couto, Ricardo

    2011-01-01

    Orthodontic appliances for skeletal anchorage are becoming increasingly more common in clinical practice. Similarly, different terms such as mini-implants, microimplants, and miniscrews have been used. There is a wide array of appliances currently on the market, in different designs and sizes, diameters, degree of titanium purity, and surface treatment. These appliances have been used for a variety of indications, including tooth retraction, intrusion, and traction. This study aimed to report the clinical case of a 19-year-old patient with a fractured mandible and to propose a novel use of mini-implants: the perioperative placement of mini-implants as anchors for maxillomandibular fixation steel wire ligatures. We concluded that this appliance provides an effective maxillomandibular fixation in patients with mandibular fracture, with little increase in the cost of surgery. PMID:23205173

  10. Changes in biting forces with implant-supported overdenture in the lower jaw: A comparison between conventional and mini implants in a pilot study.

    Science.gov (United States)

    Hasan, I; Madarlis, C; Keilig, L; Dirk, C; Weber, A; Bourauel, C; Heinemann, F

    2016-11-01

    The biting ability of patients improves noticeably after receiving implant-supported overdentures in comparison to conventional complete dentures. However, the change of biting with such treatment concepts has been quantitatively investigated in only a limited number of studies. The aim of the present study has been to measure the biting forces of edentulous patients with complete dentures and after receiving implant-supported overdentures. A total of 26 edentulous patients were included. Ten patients received two to four conventional implants (control group, Ø3.3-3.7mm, L11-13mm) and 16 patients received four to five mini implants (study group, Ø1.8-2.4mm, L13-15mm) inserted in the mandibular interforaminal region. All patients received a lower overdenture with ball/rubber ring attachments and a complete denture for the maxilla. The biting forces were measured using Prescale pressure sheets type low before the insertion of implants and after receiving implant-supported overdenture. The measured sheets were later scanned and analysed using FPD-8010E software. The range of biting forces before the insertion of implants was 80N-122N for the control group and 66-88N for the study group. After the insertion of implants, the range of biting forces increased to 167N-235N for the control group and to 81N-138N for the study group. However, the increase in biting forces after the insertion of implants was not significant for either group. No significant difference was obtained between the two implant systems. The biting forces improved after insertion of implants regardless of which implant system was used. However, the degree of improvement is noticeably related to the original bone quality of the mandible at the insertion regions of implants.

  11. Mini-implants for direct or indirect orthodontic anchorage

    NARCIS (Netherlands)

    Ren, Yijin

    2009-01-01

    DATA SOURCES: Studies were sourced using Medline, the Cochrane Library and hand searches of key orthodontic journals. STUDY SELECTION: The review was restricted to peer-review articles (randomised controlled studies, prospective clinical studies and retrospective clinical studies) dealing with mini-

  12. Optimal area of lateral mass mini-screws implanted in plated cervical laminoplasty: a radiography anatomy study.

    Science.gov (United States)

    Chen, Hua; Li, Huibo; Deng, Yuxiao; Rong, Xin; Gong, Quan; Li, Tao; Song, Yueming; Liu, Hao

    2017-04-01

    Lateral mass mini-screws used in plated cervical laminoplasty might penetrate into facet joints. The objective is to observe this complication incidence and to identify the optimal areas for 5- and 7-mm-long mini-screws to implant on lateral mass. 47 patients who underwent plated cervical laminoplasty were included. The optimal area for mini-screws implanting was set according to pre-operative 3D CT reconstruction data. Then, each posterior-lateral mass surface was divided into three regions: 7-mm region, 5-mm region, and dangerous area. The mini-screw implanted region was recorded. Post-operative CT images were used to identify whether the mini-screws penetrated into facet joints. 235 mini-plates and 470 lateral mass mini-screws were used in the study. 117 (24.9%) mini-screws penetrated 88 (37.4%) facet joints. The 5-mm-long mini-screw optimal area occupied the upper 72, 65, 65, 64, and 65 % area of the posterior-lateral mass surface for C3-7, while the 7-mm-long mini-screw optimal area encompassed the upper 54, 39, 40, 33, and 32 %. Only 7-mm-long mini-screws were used to fix the plate to the lateral mass. 4 of 240 mini-screws in 7-mm region, 67 of the 179 mini-screws in 5-mm region, and 46 of the 51 mini-screws in dangerous region penetrated into the facet joint. The differences in the rate of facet joint penetration related to region were statistically significant (P areas we proposed may help guide the mini-screw implantation positions.

  13. Comparison of topical and infiltration anesthesia for orthodontic mini-implant placement

    Science.gov (United States)

    Valieri, Matheus Miotello; de Freitas, Karina Maria Salvatore; Valarelli, Fabricio Pinelli; Cançado, Rodrigo Hermont

    2014-01-01

    Objective To compare the acceptability and effectiveness of topical and infiltration anesthesia for placement of mini-implants used as temporary anchorage devices. Methods The sample comprised 40 patients, 17 males and 23 females, whose mean age was 26 years old and who were all undergoing orthodontic treatment and in need for anchorage reinforcement. Mini-implants were bilaterally placed in the maxilla of all individuals, with infiltration anesthesia on one side and topical anesthesia on the other. These 40 patients completed two questionnaires, one before and another after mini-implant placement and pain was measured through a visual analog scale (VAS). The data collected were analyzed using descriptive statistics and the measurements of pain were compared by means of the non-parametric test of Mann-Whitney. Results It was found that 60% of patients felt more comfortable with the use of topical anesthesia for mini-implant placement; 72.5% of patients described the occurrence of pressure during placement of the anchorage device as the most unpleasant sensation of the entire process; 62.5% of patients felt more pain with the use of topical anesthesia. Conclusion It was concluded that patients had less pain with the use of infiltration anesthesia, and also preferred this type of anesthetic. PMID:24945517

  14. Comparison of topical and infiltration anesthesia for orthodontic mini-implant placement

    Directory of Open Access Journals (Sweden)

    Matheus Miotello Valieri

    2014-04-01

    Full Text Available Objective: To compare the acceptability and effectiveness of topical and infiltration anesthesia for placement of mini-implants used as temporary anchorage devices. Methods: The sample comprised 40 patients, 17 males and 23 females, whose mean age was 26 years old and who were all undergoing orthodontic treatment and in need for anchorage reinforcement. Mini-implants were bilaterally placed in the maxilla of all individuals, with infiltration anesthesia on one side and topical anesthesia on the other. These 40 patients completed two questionnaires, one before and another after mini-implant placement and pain was measured through a visual analog scale (VAS. The data collected were analyzed using descriptive statistics and the measurements of pain were compared by means of the non-parametric test of Mann-Whitney. Results: It was found that 60% of patients felt more comfortable with the use of topical anesthesia for mini-implant placement; 72.5% of patients described the occurrence of pressure during placement of the anchorage device as the most unpleasant sensation of the entire process; 62.5% of patients felt more pain with the use of topical anesthesia. Conclusion: It was concluded that patients had less pain with the use of infiltration anesthesia, and also preferred this type of anesthetic.

  15. Investigation of bacteremia induced by removal of orthodontic mini-implants

    NARCIS (Netherlands)

    Livas, Christos; Delli, Konstantina; Karapsias, Stergios; Pandis, Nikolaos; Ren, Yijin

    The aim of this study was to investigate potential occurrence of bacteremia in orthodontic patients after removal of miniscrews.The study group comprised 30 healthy subjects (17 males, 13 females) with a mean age of 24.1 years treated with self-ligating fixed appliances and mini-implant anchorage.

  16. Mini implant supported molar tubes: A novel method for attaching the molar tubes

    Directory of Open Access Journals (Sweden)

    Nitin V Muralidhar

    2017-01-01

    Full Text Available Banding or bonding procedures have been the only means of attaching molar tubes onto the permanent molar teeth till date in the field of orthodontics. This clinical innovation aims to include the use of mini implant for the purpose of attaching the molar tubes thereby eliminating the iatrogenic effects of banding and bonding of the teeth.

  17. Selective use of hand and forearm muscles during mini-implant insertion: a natural torquimeter.

    Science.gov (United States)

    Estelita, Sérgio; Janson, Guilherme; Chiqueto, Kelly; Ferreira, Eduardo; Janson, Marcos

    2012-12-01

    To compare maximum torque produced by different muscular groups and its influence on mini-implant insertion torque and fracture prevention. A prospective study involving in vivo and in vitro laboratory experiments. Eighty-seven professionals were evaluated for maximum torque produced using a screwdriver with combined action between thumb and index fingers [maximum digital torque (MDT)] and by forearm supination movement [maximum brachial torque (MBT)]. Ninety mini-implants distributed over nine different diameters and twenty commercially available mini-implants of two different diameters and trademarks were fractured to determine the fracture torque (FT). The fracture resistance index (FRI) was obtained from: FRI_MDT = FT/MDT and FRI_MBT = FT/MBT. The analysis of variance (ANOVA) and t tests were used to compare the groups. MDT was smaller than MBT and both were smaller in females. FT increased for each 0·1 mm of diameter increment. FRI_MDT was greater than FRI_MBT for all diameters. FRI_MDT>1 was found when the diameter was greater than or equal to 1·5 mm. FRI_MBT>1 occurred with diameters equal or greater than 1·7 mm for females and 1·8 mm for males. The 1.5 mm and 1.6 mm diameter of commercially available and mini-implants presented FRI_MBT1. Digital torque was 42% smaller than brachial torque, and it was mechanically safer and biologically more compatible, allowing fracture prevention of 1·5 mm or thicker mini-implant diameter due to insertion torque limitation at 15 N/cm.

  18. Immediately loaded mini dental implants as overdenture retainers: 1-Year cohort study of implant stability and peri-implant marginal bone level.

    Science.gov (United States)

    Šćepanović, Miodrag; Todorović, Aleksandar; Marković, Aleksa; Patrnogić, Vesna; Miličić, Biljana; Moufti, Adel M; Mišić, Tijana

    2015-05-01

    This 1-year cohort study investigated stability and peri-implant marginal bone level of immediately loaded mini dental implants used to retain overdentures. Each of 30 edentulous patients received 4 mini dental implants (1.8 mm × 13 mm) in the interforaminal mandibular region. The implants were immediately loaded with pre-made overdentures. Outcome measures included implant stability and bone resorption. Implant stability was measured using the Periotest Classic(®) device immediately after placement and on the 3rd and 6th weeks and the 4th, 6th and 12th months postoperatively. The peri-implant marginal bone level (PIBL) was evaluated at the implant's mesial and distal sides from the polished platform to the marginal crest. Radiographs were taken using a tailored film holder to reproducibly position the X-ray tube at the 6th week, 4th and 12th months postoperatively. The primary stability (Periotest value, PTV) measured -0.27 ± 3.41 on a scale of -8 to + 50 (lower PTV reflects higher stability). The secondary stability decreased significantly until week 6 (mean PTV = 7.61 ± 7.05) then increased significantly reaching (PTV = 6.17 ± 6.15) at 12 months. The mean PIBL measured -0.40 mm after 1 year of functional loading, with no statistically significant differences at the various follow-ups (p = 0.218). Mini dental implants placed into the interforaminal region could achieve a favorable primary stability for immediate loading. The follow-up Periotest values fluctuated, apparently reflecting the dynamics of bone remodeling, with the implants remaining clinically stable (98.3%) after 1 year of function. The 1-year bone resorption around immediately loaded MDIs is within the clinically acceptable range for standard implants. Copyright © 2014 Elsevier GmbH. All rights reserved.

  19. New approach towards mini dental implants and small-diameter implants: an option for long-term prostheses.

    Science.gov (United States)

    Gleiznys, Alvydas; Skirbutis, Gediminas; Harb, Ali; Barzdziukaite, Ingrida; Grinyte, Ieva

    2012-01-01

    BACKGROUND. Mini dental implants (MDI) and small diameter implants (SDI) have been extensively used as temporary or orthodontic anchorage; however there have been studies that proved their availability as a mean for long term prosthodontics. Our aim was to review the indications, advantages of MDI and SDI, and their long-term survival. METHODS. Computerized searches were conducted for clinical studies between year 2000 and 2011 that involved either implants with 3.3 mm diameter or less, used in prosthodontics; or provided a follow up of MDI or SDI duration of at least 4 months following implant placement including survival rate data. All studies about implants used in orthodontics were excluded. The range of available MDI and SDI has been found in cataloges of the companies: 3M ESPE IMTEC, Bicon Dental, Zimmer, Implant Direct, Intra lock, Hiossen, Simpler Implant, KAT Implants, OCO Biomedical, American Dental Implant. RESULTS. 41 studies meeting the above criteria were selected, 22 out of them reviewed survival rates of MDI and SDI. The follow up duration varried from 4 months to 8 years with survival rates between 91.17 and 100%. Nevertheless, the companies showed a big variety of MDI and SDI provided in the market for long term prostheses. CONCLUSIONS. Implants with small diameters can be used successfully in a variety of clinical situations. Less surgical time, less postoperative pain, ability of direct loading after surgery with no harm to bone and cost effectiveness are the advantages. The reduced surface implants require correct treatment planning so that the loading force would not cause bone loss or implant failure. MDI and SDI show high survival rates, but special cautions for bone quality and good oral hygiene should be maintained.

  20. Metallurgical Behavior of Ti-6Al-4V Alloy Mini-Implants as a Temporary Anchorage Device in Orthodontics Applications

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    Mendoza-Bravo Ivan

    2014-01-01

    Full Text Available The application of mini implants as a temporary anchorage device in orthodontics is a new technique that allows the movement of teeth in an efficient and predictable way. Although they have started to be used in Germany, Japan and South Korea, there is still the need to analyze and diffuse the advantages this procedure can offer over the traditional techniques. The objective of this research work was to analyze the integrity of Ti-6Al-4V mini implants temporary employed for 4 months on three patients as an anchorage device. The mini implants were analyzed by means of electron scanning microscopy in order to determine superficial and microstructural changes as well as the interaction with human tissue. Results showed the presence of wear on the thread zone caused during the insertion into the maxilar bone. The adherence of organic tissue was also observed on two mini-implants.

  1. Mini-implant-borne Pendulum B appliance for maxillary molar distalisation: design and clinical procedure.

    Science.gov (United States)

    Wilmes, Benedict; Katyal, Vandana; Drescher, Dieter

    2014-11-01

    A treatment objective of upper molar distalisation may often be required during the correction of a malocclusion. Distalisation is not only indicated for the management of Class II patients, but also for Class III surgery patients who require decompensation in the upper arch if upper incisor retrusion is needed. Unfortunately, most conventional intra-oral devices for non-compliance maxillary molar distalisation experience anchorage loss. A Pendulum type of appliance and a mini-implant-borne distalisation mechanism have been designed which can be inserted at chair-side, without a prior laboratory procedure and immediately after mini-implant placement. For re-activation purposes, a distal screw may be added to the Pendulum B appliance.

  2. Analysis on the stress of the bone surrounding mini-implant with different diameters and lengths under torque.

    Science.gov (United States)

    Lu, Yingjuan; Chang, Shaohai; Ye, Jiantao; Ye, Yushan; Yu, Yansong

    2015-01-01

    The purpose of this study is to compare the stress of the bone around the mini-implant under the two kinds of force: the composite force which contains torque and traditional single force. There were 96 finite element models formed by the combination of mini-implant and bone, with diameters of 1.2 mm, 1.6 mm, 2.0 mm and corresponding length being 6 mm, 8 mm, 10 mm, 12 mm, respectively. Each size corresponded to 8 models. Group SF (each size n=4) was loaded with 200 g single force, while Group CF (each size n=4) was loaded with composite force which contained 6N mm torque and 200 g single force. The maximum equivalent stress (Max EQS) of the bone surrounding mini implant with different loading directions was calculated, and the relationship of force direction, diameter and length was also evaluated. The Max EQS of Group CF was higher than that of Group SF. The effect of force direction on the stress was related to the diameter of mini implant, but had nothing to do with its length. The Max EQS of the cortical bone around mini implant in Group CF was higher (Pdifference (P>0.05) between Group SF and Group CF in terms of bone stress when the diameter of mini implant was 1.6 mm or 2.0 mm. In our study, it is demonstrated that the diameter of mini-implant is better to be larger than 1.2 mm when a mini-implant is used in a torque control of tooth. The impact of this feature in the clinical setting needs to be verified.

  3. The ASTRI Mini-Array Software System

    CERN Document Server

    ,

    2013-01-01

    ASTRI ("Astrofisica con Specchi a Tecnologia Replicante Italiana") is a Flagship Project financed by the Italian Ministry of Education, University and Research, and led by INAF, the Italian National Institute of Astrophysics. Main goals of the ASTRI project are the realization of an end-to-end prototype of a Small Size Telescope (SST) for the Cherenkov Telescope Array (CTA) in a dual-mirror configuration (SST-2M) and, subsequently, of a mini-array composed of a few SST-2M telescopes to be placed at the final CTA Southern Site. Here we present the main features of the Mini-Array Software System (MASS) that has a central role in the success of the ASTRI Project and will also serve as a prototype for the CTA software system. The MASS will provide a set of tools to prepare an observing proposal, to perform the observations specified therein (monitoring and controlling all the hardware components of each telescope), to analyze the acquired data online and to store/retrieve all the data products to/from the archive...

  4. Velocity control of mini-UAV using a helmet system

    OpenAIRE

    Téllez-Guzmán, J. J.; Gomez-Balderas, Jose-Ernesto; Marchand, Nicolas; Castillo, Pedro; Colmenares Vazquez, J; Álvarez-Muñoz, J. U.; Dumon, Jonathan

    2015-01-01

    International audience; The usage of a helmet to command a mini-unmanned aerial vehicle (mini-UAV), is a telepresence system that connects the operator to the vehicle. This paper proposes a system which remotely allows the connection of a pilot's head motion and the 3D movements of a mini-UAVs. Two velocity control algorithms have been tested in order to manipulate the system. Results demonstrate that these movements can be used as reference inputs of the controller of the mini-UAV.

  5. Dental Implant Systems

    Science.gov (United States)

    Oshida, Yoshiki; Tuna, Elif B.; Aktören, Oya; Gençay, Koray

    2010-01-01

    Among various dental materials and their successful applications, a dental implant is a good example of the integrated system of science and technology involved in multiple disciplines including surface chemistry and physics, biomechanics, from macro-scale to nano-scale manufacturing technologies and surface engineering. As many other dental materials and devices, there are crucial requirements taken upon on dental implants systems, since surface of dental implants is directly in contact with vital hard/soft tissue and is subjected to chemical as well as mechanical bio-environments. Such requirements should, at least, include biological compatibility, mechanical compatibility, and morphological compatibility to surrounding vital tissues. In this review, based on carefully selected about 500 published articles, these requirements plus MRI compatibility are firstly reviewed, followed by surface texturing methods in details. Normally dental implants are placed to lost tooth/teeth location(s) in adult patients whose skeleton and bony growth have already completed. However, there are some controversial issues for placing dental implants in growing patients. This point has been, in most of dental articles, overlooked. This review, therefore, throws a deliberate sight on this point. Concluding this review, we are proposing a novel implant system that integrates materials science and up-dated surface technology to improve dental implant systems exhibiting bio- and mechano-functionalities. PMID:20480036

  6. Dental Implant Systems

    Directory of Open Access Journals (Sweden)

    Yoshiki Oshida

    2010-04-01

    Full Text Available Among various dental materials and their successful applications, a dental implant is a good example of the integrated system of science and technology involved in multiple disciplines including surface chemistry and physics, biomechanics, from macro-scale to nano-scale manufacturing technologies and surface engineering. As many other dental materials and devices, there are crucial requirements taken upon on dental implants systems, since surface of dental implants is directly in contact with vital hard/soft tissue and is subjected to chemical as well as mechanical bio-environments. Such requirements should, at least, include biological compatibility, mechanical compatibility, and morphological compatibility to surrounding vital tissues. In this review, based on carefully selected about 500 published articles, these requirements plus MRI compatibility are firstly reviewed, followed by surface texturing methods in details. Normally dental implants are placed to lost tooth/teeth location(s in adult patients whose skeleton and bony growth have already completed. However, there are some controversial issues for placing dental implants in growing patients. This point has been, in most of dental articles, overlooked. This review, therefore, throws a deliberate sight on this point. Concluding this review, we are proposing a novel implant system that integrates materials science and up-dated surface technology to improve dental implant systems exhibiting bio- and mechano-functionalities.

  7. Influência da largura do septo inter-radicular sobre a estabilidade dos mini-implantes Influence of inter-root septum width on mini-implant stability

    Directory of Open Access Journals (Sweden)

    Mariana Pracucio Gigliotti

    2011-04-01

    Full Text Available OBJETIVO: este estudo teve como objetivo avaliar a influência da largura do septo inter-radicular no local de inserção de mini-implantes autoperfurantes sobre o grau de estabilidade desses dispositivos de ancoragem. MÉTODOS: a amostra consistiu de 40 mini-implantes inseridos entre as raízes do primeiro molar e segundo pré-molar superiores de 21 pacientes, com o intuito de fornecer ancoragem para retração anterior. A largura do septo no local de inserção (LSI foi mensurada nas radiografias pós-cirúrgicas e, sob esse aspecto, os mini-implantes foram divididos em dois grupos: grupo 1 (áreas críticas, LSI3mm. A estabilidade dos mini-implantes foi avaliada mensalmente pela quantificação do grau de mobilidade e a partir dessa variável foi calculada a proporção de sucesso. Avaliou-se também: a quantidade de placa, altura de inserção, grau de sensibilidade e período de observação. RESULTADOS: os resultados obtidos demonstraram que não houve diferença estatisticamente significativa para o grau de mobilidade e proporção de sucesso entre os mini-implantes inseridos em septos de largura mesiodistal crítica e não crítica. A proporção de sucesso total encontrada foi de 90% e nenhuma variável demonstrou estar relacionada ao insucesso dos mini-implantes. No entanto, observou-se maior sensibilidade nos pacientes cujos mini-implantes apresentavam mobilidade, e que a falha desses dispositivos de ancoragem ocorria logo após sua inserção. CONCLUSÃO: a largura do septo inter-radicular no local de inserção não interferiu na estabilidade dos mini-implantes autoperfurantes avaliados neste estudo.OBJECTIVE: The purpose of this study was to evaluate the influence of the inter-radicular septum width in the insertion site of self-drilling mini-implants on the stability degree of these anchorage devices. METHODS: The sample consisted of 40 mini-implants inserted in the inter-radicular septum between maxillary second premolars and

  8. Primary Stability of Self-Drilling and Self-Tapping Mini-Implant in Tibia of Diabetes-Induced Rabbits

    Directory of Open Access Journals (Sweden)

    Jea-Beom Park

    2014-01-01

    Full Text Available Objective. This study aimed to evaluate effects of type 1 diabetes mellitus and mini-implant placement method on the primary stability of mini-implants by comparing mechanical stability and microstructural/histological differences. Methods. After 4 weeks of diabetic induction, 48 mini-implants (24 self-tapping and 24 self-drilling implants were placed on the tibia of 6 diabetic and 6 normal rabbits. After 4 weeks, the rabbits were sacrificed. Insertion torque, removal torque, insertion energy, and removal energy were measured with a surgical engine on 8 rabbits. Remaining 4 rabbits were analyzed by microcomputed tomography (micro-CT and bone histomorphometry. Results. Total insertion energy was higher in self-drilling groups than self-tapping groups in both control and diabetic groups. Diabetic groups had more trabecular separation in bone marrow than the control groups in both SD and ST groups. Micro-CT analysis showed deterioration of bone quality in tibia especially in bone marrow of diabetic rabbits. However, there was no statistically significant correlation between self-drilling and self-tapping group for the remaining measurements in both control and diabetic groups. Conclusions. Type 1 diabetes mellitus and placement method of mini-implant did not affect primary stability of mini-implants.

  9. Customized SmartPeg for measurement of resonance frequency of mini dental implants.

    Science.gov (United States)

    Dhaliwal, Jagjit Singh; Albuquerque, Rubens F; Fakhry, Ali; Kaur, Sukhbir; Feine, Jocelyne S

    2017-12-01

    One-piece narrow diameter implants (NDIs) have been recommended as "Single-tooth replacements in the anterior zones, single posterior, multiple-unit fixed dental prosthesis (FDP), edentulous jaws to be rehabilitated with FDP, and edentulous jaws rehabilitation with overdentures in situations with reduced mesiodistal space or reduced ridge width." (ITI consensus 2013). Since NDIs can be immediately loaded, it is important to be able to carry out stability testing. We developed and validated a customized SmartPeg for this type of implant to measure the Implant Stability Quotient (ISQ). The ISQ of mini dental implants (MDIs) was measured and compared with the stability of standard and in a rabbit model. The aim of the study is to test the feasibility of a customized SmartPeg for resonance frequency measurement of single-piece mini dental implants and to compare primary stability of a standard and the mini dental implant (3M™ESPE™ MDI) in a rabbit model after 6 weeks of healing. Eight New Zealand white rabbits were used for the study. The protocol was approved by the McGill University Animal Ethics Review Board. Sixteen 3M™ESPE™ MDI and equal number of standard implants (Ankylos® Friadent, Dentsply) were inserted into the tibia/femur of the rabbits and compared. Each rabbit randomly received two 3M™ESPE™ MDI and two Ankylos® implants in each leg. ISQ values were measured with the help of an Osstell ISQ device using custom-made SmartPegs for the MDIs and implant-specific SmartPegs™ (Osstell) for the Ankylos®. Measurements were obtained both immediately following implant placement surgery and after a 6-week healing period. Each reading was taken thrice and their average compared using Wilcoxon matched pairs signed-rank tests. The median ISQ and interquartile range (IQR) values were 53.3 (8.3) at insertion and 60.5 (5.5) at 6 weeks for the 3M™ESPE™MDI and, respectively, 58.5 (4.75) and 65.5 (9.3) for the Ankylos® implant. These values also indicate

  10. Insertion torque versus mechanical resistance of mini-implants inserted in different cortical thickness

    Science.gov (United States)

    Santos, Renata de Faria; Ruellas, Antonio Carlos de Oliveira; Fernandes, Daniel Jogaib; Elias, Carlos Nelson

    2014-01-01

    Objective This study aimed to measure insertion torque, tip mechanical resistance to fracture and transmucosal neck of mini-implants (MI) (Conexão Sistemas de PróteseT), as well as to analyze surface morphology. Methods Mechanical tests were carried out to measure the insertion torque of MIs in different cortical thicknesses, and tip mechanical resistance to fracture as well as transmucosal neck of MIs. Surface morphology was assessed by scanning electron microscopy (SEM) before and after the mechanical tests. Results Values of mechanical resistance to fracture (22.14 N.cm and 54.95 N.cm) were higher and statistically different (P 0.05) to torsional fracture in the tip of MI (22.14 N.cm) when 3 mm cortical thickness (16.11 N.cm) and dense bone (23.95 N.cm) were used. Torsional fracture of the transmucosal neck (54.95 N.cm) was higher and statistically different (P implants tested presented adequate surface morphology. The resistance of mini-implants to fracture safely allows placement in 1 and 2-mm cortical thickness. However, in 3-mm cortical thickness and dense bones, pre-drilling with a bur is recommended before insertion. PMID:25162571

  11. Surface analysis of an encapsulation membrane after its implantation in mini-pigs

    Energy Technology Data Exchange (ETDEWEB)

    Henry, Marie [Universite Catholique de Louvain, PCPM, Croix du Sud 1, B1348 Louvain-La-Neuve (Belgium); Ulrichs, Karin [University of Wuerzburg Hospital (Germany); Moskalenko, Vasily [University of Wuerzburg Hospital (Germany); Bonneau, Michel [Institut National de la Recherche Agronomique, Paris (France); Kang, Chantal [Institut National de la Recherche Agronomique, Paris (France); Belcourt, Alain [Centre Europeen d' Etude du Diabete, Strasbourg (France); Bertrand, Patrick [Universite Catholique de Louvain, PCPM, Croix du Sud 1, B1348 Louvain-La-Neuve (Belgium)

    2007-03-01

    The biocompatibility of membranes aiming at being a part of a bioartificial pancreas has been tested. For that purpose, we have studied a polycarbonate membrane surface after its implantation in mini-pigs. The membranes were made hydrophilic by an argon plasma surface treatment followed by a dipping in a hydrophilic polymer solution. Two polymers were tested: polyvinylpyrrolidone (PVP) and hydroxypropylmethylcellulose (HPMC). To test their biocompatibility, an encapsulation device for pig Langerhans islets, with external membranes treated as described above, was implanted in different mini-pigs. The pigs received no further treatment. The devices were explanted after in vivo exposure and the membranes were analysed by XPS (x-ray photoelectron spectroscopy) and ToF-SIMS (time-of-flight secondary ion mass spectrometry). After this time, the substrate with the PVP or HPMC treatment was still detected on the different samples. The surface treatment signal, however, was attenuated. This is explained by the detection of other components partly covering the surface. XPS and ToF-SIMS analyses revealed the presence of biological molecules on the two faces of the membrane: the outside face in contact with the biological environment and the inside face in contact with the device. ToF-SIMS images show the inhomogeneity of the biological molecules on the membrane surface. In conclusion, biological molecules adhered to the encapsulation membrane surface after implantation but the surface treatments remained unaltered.

  12. Intrusão dentária utilizando mini-implantes

    OpenAIRE

    de Araújo, Telma Martins; Nascimento, Mauro Henrique Andrade; Franco,Fernanda Catharino Menezes; Bittencourt,Marcos Alan Vieira

    2008-01-01

    P. 36-48,set./out. INTRODUÇÃO: dentre os diversos tipos de movimentos dentários induzidos ortodonticamente, o de intrusão é, sem dúvida, um dos mais difíceis de serem conseguidos. A mecânica intrusiva convencional, apesar de viável, é complexa, no que diz respeito ao controle de seus efeitos colaterais. Isso, em grande parte, refere-se à dificuldade em se obter uma ancoragem satisfatória. Neste contexto, os mini-implantes, por oferecerem efetiva ancoragem esquelética, têm se mostrado de ex...

  13. Grau de aceitação de mini-implantes por pacientes em tratamento ortodôntico: estudo preliminar The mini-implants acceptance rate by patients in orthodontic treatments: a preliminary study

    Directory of Open Access Journals (Sweden)

    Larissa Bustamante Capucho Brandão

    2008-10-01

    Full Text Available OBJETIVOS: os mini-implantes atualmente representam um grande avanço na Ortodontia, por proporcionarem máxima ancoragem com o mínimo de cooperação dos pacientes. No entanto, ainda existem algumas dúvidas quanto ao uso destes dispositivos temporários de ancoragem no que se refere, principalmente, aos aspectos psicológicos de aceitação pelos pacientes durante o tratamento ortodôntico. METODOLOGIA: dez pacientes adultos, portadores de má oclusão de Classe I, com biprotrusão, que foram submetidos a tratamento ortodôntico com a colocação de quatro mini-implantes nos arcos dentários, entre os primeiros molares e segundos pré-molares superiores e inferiores, responderam a um questionário, com o objetivo de avaliar as condições de aceitação dos mini-implantes. RESULTADOS: as respostas indicaram que a maioria dos pacientes aceitou prontamente o procedimento, estavam satisfeitos e recomendariam para outros pacientes (90%, enquanto 50% tiveram alguma preocupação com os procedimentos cirúrgicos e os outros 50% não relataram nenhum desconforto. O tempo médio de tolerância a partir da colocação foi de 3 dias e a maioria tolerou os implantes durante todo o tratamento ortodôntico. CONCLUSÕES: pôde-se concluir que os mini-implantes foram aceitos de forma positiva pela maioria dos pacientes submetidos ao tratamento ortodôntico.OBJECTIVE: Actually, mini-implants as anchorage resources have been spotlight in Orthodontics, providing maximum anchorage with minimum patient's cooperation. However, there are still some restrictions regarding the use of these temporary anchorage devices, and among these, the psychological aspects and the patient's acceptance, which still not properly evaluated. METHODS: Ten adults patients, with Class I biprotrusion malocclusion, that were submitted to orthodontic treatment with the implantation of four mini-implants, in the dental arches, among upper and lower first molar and second premolar teeth, in

  14. Camouflage of Severe Skeletal Class II Gummy Smile Patient Treated Nonsurgically with Mini Implants

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    Irfan Qamruddin

    2014-01-01

    Full Text Available Skeletal class II has always been a challenge in orthodontics and often needs assistance of surgical orthodontics in nongrowing patients when it presents with severe discrepancy. Difficulty increases more when vertical dysplasia is also associated with sagittal discrepancy. The advent of mini implants in orthodontics has broadened the spectrum of camouflage treatment. This case report presents a 16-year-old nongrowing girl with severe class II because of retrognathic mandible, and anterior dentoalveolar protrusion sagittally and vertically resulted in severe overjet of 13 mm and excessive display of incisors and gums. Both maxillary central incisors were trimmed by general practitioner few years back to reduce visibility. Treatment involved use of micro implant for retraction and intrusion of anterior maxillary dentoalveolar segment while lower incisors were proclined to obtain normal overjet, and overbite and pleasing soft tissue profile. Smile esthetics was further improved with composite restoration of incisal edges of both central incisors.

  15. Mini-Implants in the Anchorage Armamentarium: New Paradigms in the Orthodontics

    Directory of Open Access Journals (Sweden)

    Masaru Yamaguchi

    2012-01-01

    Full Text Available Paradigms have started to shift in the orthodontic world since the introduction of mini-implants in the anchorage armamentarium. Various forms of skeletal anchorage, including miniscrews and miniplates, have been reported in the literature. Recently, great emphasis has been placed on the miniscrew type of temporary anchorage device (TAD. These devices are small, are implanted with a relatively simple surgical procedure, and increase the potential for better orthodontic results. Therefore, miniscrews not only free orthodontists from anchorage-demanding cases, but they also enable clinicians to have good control over tooth movement in 3 dimensions. The miniplate type also produces significant improvements in treatment outcomes and has widened the spectrum of orthodontics. The purpose of this paper is to update clinicians on the current concepts and versatile uses and clinical applications of skeletal anchorage in orthodontics.

  16. Mini-Implants in the Anchorage Armamentarium: New Paradigms in the Orthodontics

    Science.gov (United States)

    Yamaguchi, Masaru; Inami, Toshihiro; Ito, Ko; Kasai, Kazutaka; Tanimoto, Yasuhiro

    2012-01-01

    Paradigms have started to shift in the orthodontic world since the introduction of mini-implants in the anchorage armamentarium. Various forms of skeletal anchorage, including miniscrews and miniplates, have been reported in the literature. Recently, great emphasis has been placed on the miniscrew type of temporary anchorage device (TAD). These devices are small, are implanted with a relatively simple surgical procedure, and increase the potential for better orthodontic results. Therefore, miniscrews not only free orthodontists from anchorage-demanding cases, but they also enable clinicians to have good control over tooth movement in 3 dimensions. The miniplate type also produces significant improvements in treatment outcomes and has widened the spectrum of orthodontics. The purpose of this paper is to update clinicians on the current concepts and versatile uses and clinical applications of skeletal anchorage in orthodontics. PMID:22719763

  17. Pathological impairments induced by interstitial implantation of 125I Seeds in spinal canal of banna mini-pigs

    Directory of Open Access Journals (Sweden)

    Yang Zuozhang

    2012-03-01

    Full Text Available Abstract Background Use a banna mini-pig to set up 125I implantation model, and investigate the consequence of radiation-related impairments. Methods In present study, 125I seeds were implanted into spinal canal of T13 level of spine in banna mini-pigs. After operation, the pigs were raised up to 8 months, behavior changes were recorded within this period. After 8 months, spinal cords were collected for pathological analysis. Results In this study, a 125I brachytherapy animal model had been successfully established, in the model group, the banna pigs' Tarlov scale decreased from 5 to 2.57 ± 0.36, significant cellular impairments were noted by pathological analysis. Conclusions Without any protection and operation improvement, 125I implantation can cause serious histological impairments and moving difficulty for banna mini-pigs; this present research provides an alternative tool to study spinal 125I brachytherapy.

  18. Stability of smooth and rough mini-implants: clinical and biomechanical evaluation - an in vivostudy

    Directory of Open Access Journals (Sweden)

    Giselle Naback Lemes Vilani

    2015-10-01

    Full Text Available Objective: To compare in vivo orthodontic mini-implants (MI of smooth (machined and rough (acid etched surfaces, assessing primary and secondary stability.Methods:Thirty-six (36 MI were inserted in the mandibles of six (6 dogs. Each animal received six (6 MI. In the right hemiarch, three (3 MI without surface treatment (smooth were inserted, whereas in the left hemiarch, another three (3 MI with acid etched surfaces (rough were inserted. The two distal MI in each hemiarch received an immediate load of 1.0 N for 16 weeks, whereas the MI in the mesial extremity was not subject to loading. Stability was measured by insertion and removal torque, initial and final mobility and by inter mini-implant distance.Results:There was no statistical behavioral difference between smooth and rough MI. High insertion torque and reduced initial mobility were observed in all groups, as well as a reduction in removal torques in comparison with insertion torque. Rough MI presented higher removal torque and lower final mobility in comparison to smooth MI. MI did not remain static, with displacement of rough MI being smaller in comparison with smooth MI, but with no statistical difference.Conclusions:MI primary stability was greater than stability measured at removal. There was no difference in stability between smooth and rough MI when assessing mobility, displacement and insertion as well as removal torques.

  19. Mesialização de molares com ancoragem em mini-implantes Mesial movement of molars with mini-implants anchorage

    Directory of Open Access Journals (Sweden)

    Marcos Janson

    2008-10-01

    Full Text Available INTRODUÇÃO: é muito comum, na rotina do consultório odontológico, especialmente em Ortodontia, o paciente, após avaliar o plano de tratamento proposto, questionar sobre a possibilidade de fechamento de espaços presentes, ocasionados pela perda de dentes permanentes. O ortodontista, frente a essa questão, tem que avaliar diversos fatores, tais como a má oclusão presente, a integridade do osso e das raízes, o tempo de tratamento e a geometria do posicionamento dentário, que é o que permite avaliar se, com o fechamento dos espaços e, conseqüentemente, a perda de ancoragem dos segmentos anteriores, a finalização estará de acordo com os ideais que regem a especialidade. Com o advento dos mini-implantes, as possibilidades desta abordagem terapêutica aumentaram, pois o efeito adverso da perda de ancoragem pode ser eliminado e, com isso, o paciente pode ser beneficiado. No entanto, os outros fatores envolvidos, assim como a mecânica do movimento, requerem especial atenção. OBJETIVOS: no presente artigo serão abordados os fatores envolvidos neste tipo de tratamento, o raciocínio na tomada de decisões e os detalhes importantes que devem ser observados durante a condução da mecânica, ilustrados com casos clínicos.INTRODUCTION: It's routine, especially at the orthodontic office, the patient, after the assessment of the proposed treatment plan, answer about the possibility of closing their edentulous spaces caused by missed permanent teeth. In these situations, several factors must be evaluated, like the present malocclusion, the bone and roots integrity, the treatment time and the geometry of teeth positioning, that is what permits to assess if the loss of anchorage from the anterior segments, during the space closure, would permit the occlusion to end within the orthodontic ideals. With the mini-implants, the possibilities of this therapeutic approach have been improved, since the adverse effects are eliminated with the

  20. Comportamiento metalúrgico de mini implantes de Ti-6Al-4V como anclaje temporal en aplicaciones de ortodoncia

    OpenAIRE

    Ivan Mendoza-Bravo; José Antonio Arias-González; Doris Ivette Villalobos-Vera; Héctor Ruiz-Reyes

    2014-01-01

    El uso de mini implantes como sistema de anclaje temporal en ortodoncia, es una técnica relativamente nueva que permite el movimiento de los dientes de una manera eficiente y predecible. A pesar de que se han empezado a utilizar en diversos países como Alemania, Japón y Corea del Sur, aún existe la necesidad de analizar y dar a conocer las ventajas de este procedimiento sobre los tratamientos tradicionales. En este trabajo se analizó la integridad de mini implantes fabricados de una aleación ...

  1. Peri-implant biomechanical responses to standard, short-wide, and mini implants supporting single crowns under axial and off-axial loading (an in vitro study).

    Science.gov (United States)

    Kheiralla, Lamia Sayed; Younis, Jihan Farouk

    2014-02-01

    This study compared the biomechanical responses of 3 single crowns supported by 3 different implants under axial and off-axial loading. A standard implant (3.75 mm diameter, 13 mm length), a mini implant (3 mm diameter, 13 mm length), and a short-wide implant (5.7 mm diameter, 8 mm length) were embedded in epoxy resin by the aid of a surveyor to ensure their parallelism. Each implant supported a full metal crown made of Ni-Cr alloy with standardized dimensions. Strain gauges and finite element analysis (FEA) were used to measure the strain induced under axial and off-axial functional loads of 300 N. Results showed that mini implants recorded the highest microstrains, under both axial and off-axial loading. All implants showed a considerable increase in strain values under off-axial loading. Standard and short-wide implants proved to be preferable in supporting crowns, as the standard implant showed the lowest strains under axial and off-axial loading using FEA simulation, while the short-wide implant showed the lowest strains under nonaxial loading using strain gauge analysis.

  2. Venous Obstruction Following Pacemaker or Implantable Cardioverter-Defibrillator Implantation, Mini Review

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    Mohammad Ali Akbarzadeh

    2016-08-01

    Full Text Available Venous obstruction is relatively frequent following permanent pacemaker or implantable cardioverter-defibrillator (ICD implantation. However, most of them are asymptomatic. Although the exact risk factor for this complication is not known, number of leads, heart failure and infection may prone the patient to this complication. The goal standard for detection of vein stenosis is venography; however, ultrasound sonography has an acceptable accuracy. Anticoagulant therapy may be considered for symptomatic patients. For device upgrading, non-functional leads removal, venoplasty and rarely surgical treatment may be indicated.

  3. Mini-RPV Launch System Conceptual Study

    Science.gov (United States)

    1978-12-01

    are needed to produce total launch forces sufficient to launch mini-RPV’s. 4. Votta , F. A. Jr.;THE THEORY AND DESIGN OF LONG DEFLECTION, CONSTANT...Amendment 1, 29 September 1966. 4. Votta , F. A., Jr., THE THEORY AND DESIGN OF LONG DEFLECTION, CONSTANT FORCE SPRING ELEMENTS, Transactions of the ASME

  4. Immediate versus delayed loading of strategic mini dental implants for the stabilization of partial removable dental prostheses: a patient cluster randomized, parallel-group 3-year trial.

    Science.gov (United States)

    Mundt, Torsten; Al Jaghsi, Ahmad; Schwahn, Bernd; Hilgert, Janina; Lucas, Christian; Biffar, Reiner; Schwahn, Christian; Heinemann, Friedhelm

    2016-07-30

    Acceptable short-term survival rates (>90 %) of mini-implants (diameter implants as strategic abutments for a better retention of partial removable dental prosthesis (PRDP) are not available. The purpose of this study is to test the hypothesis that immediately loaded mini-implants show more bone loss and less success than strategic mini-implants with delayed loading. In this four-center (one university hospital, three dental practices in Germany), parallel-group, controlled clinical trial, which is cluster randomized on patient level, a total of 80 partially edentulous patients with unfavourable number and distribution of remaining abutment teeth in at least one jaw will receive supplementary min-implants to stabilize their PRDP. The mini-implant are either immediately loaded after implant placement (test group) or delayed after four months (control group). Follow-up of the patients will be performed for 36 months. The primary outcome is the radiographic bone level changes at implants. The secondary outcome is the implant success as a composite variable. Tertiary outcomes include clinical, subjective (quality of life, satisfaction, chewing ability) and dental or technical complications. Strategic implants under an existing PRDP are only documented for standard-diameter implants. Mini-implants could be a minimal invasive and low cost solution for this treatment modality. The trial is registered at Deutsches Register Klinischer Studien (German register of clinical trials) under DRKS-ID: DRKS00007589 ( www.germanctr.de ) on January 13(th), 2015.

  5. Bone stress for a mini-implant close to the roots of adjacent teeth--3D finite element analysis.

    Science.gov (United States)

    Motoyoshi, M; Ueno, S; Okazaki, K; Shimizu, N

    2009-04-01

    This study aimed to evaluate stress in the bone when an orthodontic mini-implant is close to the roots of adjacent teeth using finite element models (FEMs), and to investigate the causes of the high implant failure rate in the mandible. Four FEMs were used: the implant touches nothing; the implant touches the surface of the periodontal membrane; part of the screw thread is embedded in the periodontal membrane; and the implant touches the root. The effect of cortical bone thickness was evaluated using values of 1, 2 and 3 mm. Maximum stress value and stress distribution on the bone elements was determined. Maximum stress on the bone increased when the mini-implant was close to the root. When the implant touched the root, stress increased to 140 MPa or more, and bone resorption could be predicted. Stress was higher for a cortical bone thickness of 2 mm than for other thicknesses. Cortical bone 2 mm thick had a higher risk for bone resorption. A mandible with an average cortical bone thickness of 2 mm may have a higher risk for implant loosening than a maxilla with the same degree of root proximity, which may be related to the lower success rate in the mandible.

  6. Orthodontic Protocol Using Mini-Implant for Class II Treatment in Patient with Special Needs

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    Fernando Pedrin Carvalho Ferreira

    2016-01-01

    Full Text Available Improving facial and dental appearance and social interaction are the main factors for special needs (SN patients to seek orthodontic treatment. The cooperation of SN patients and their parents is crucial for treatment success. Objective. To show through a case report the satisfactory results, both functional and esthetic, in patients with intellectual disability, congenital nystagmus, and severe scoliosis. Materials Used. Pendulum device with mini-implants as anchorage unit. Results. Improvement of facial and dental esthetics, correction of Class II malocclusion, and no root resorption shown in the radiographic follow-up. Conclusion. Knowing the limitations of SN patients, having a trained team, motivating and counting on the cooperation of parents and patients, and employing quick and low-cost orthodontic therapy have been shown to be the essential factors for treatment success.

  7. Clinical and radiological investigations of mandibular overdentures supported by conventional or mini-dental implants: A 2-year prospective follow-up study.

    Science.gov (United States)

    Temizel, Sonay; Heinemann, Friedhelm; Dirk, Cornelius; Bourauel, Christoph; Hasan, Istabrak

    2017-02-01

    Conventional dental implants are not applicable in the mandibular interforaminal region if bone volume is limited. Mini-dental implants offer an alternative means of supporting mandibular overdentures in a narrow residual ridge, without additional surgery. The purpose of this nonrandomized clinical trial was to compare the ability of mini-dental implants with that of conventional dental implants in supporting mandibular overdentures during a 2-year clinical follow-up. Bone quality, bone resorption, implant stability, and oral health were assessed radiographically. A total of 32 participants with edentulism were included. Twenty-two participants (99 implants) received 4 to 5 mini-dental implants (diameter: 1.8-2.4 mm; length: 13-15 mm, study group), and 10 participants (35 implants) received 2 to 4 conventional dental implants (diameter: 3.3-3.7 mm; length: 11-13 mm, control group). The selection of the participants in the study or control group was based on the available bone volume in the mandible. The selection was not randomized. The density of cortical bone thickness was measured in Hounsfield units (HU) from computed tomography data, and patients were followed for 2 years. The participants were examined 3, 6, 12, and 24 months after surgery. Primary stability immediately after the insertion of dental implants (Periotest), secondary stability 6 months after implantation, modified plaque, bleeding on probing indices, and probing depth were measured and analyzed statistically (α=.05). The mean HU value 6 months after implantation in the participants who received mini-dental implants was significantly (P=.035) higher (1250 HU) than that in the participants who received conventional dental implants (1100 HU). The probing depths around the conventional dental implants (1.6 and 1.8 mm, respectively) were significantly higher than those around the mini-dental implants (1.3 and 1.2 mm, respectively) 12 and 24 months after surgery, respectively (Pdental implants were

  8. Avaliação da densidade óssea para instalação de mini-implantes Bone density assessment for mini-implants positioning

    Directory of Open Access Journals (Sweden)

    Marlon Sampaio Borges

    2010-12-01

    Full Text Available INTRODUÇÃO: além da espessura da cortical óssea e da largura dos espaços inter-radiculares, a densidade óssea é fator primordial para a eficiência dos mini-implantes usados como recurso de ancoragem. OBJETIVO: nesse estudo, pretendeu-se avaliar a densidade óssea alveolar e basal maxilar e mandibular, em unidades Hounsfield (HU. MÉTODOS: em onze arquivos de imagens tomográficas computadorizadas Cone-Beam, de indivíduos adultos, foram obtidas 660 medidas das densidades ósseas alveolar (corticais vestibular e lingual, do osso medular e basal (maxilar e mandibular. Os valores foram obtidos através do software Mimics 10.01 (Materialise, Bélgica. RESULTADOS: maxila - a densidade da cortical vestibular na faixa de osso alveolar variou de 438 a 948HU, e a lingual de 680 a 950HU; já o osso medular variou de 207 a 488HU; a densidade da cortical vestibular na faixa de osso basal apresentou uma variação de 672 a 1380HU e o osso medular de 186 a 420HU. Mandíbula - a variação do osso na cortical vestibular na faixa de osso alveolar foi de 782 a 1610HU, na cortical lingual alveolar de 610 a 1301HU, e na medular de 224 a 538; a densidade na área basal foi de 1145 a 1363HU na cortical vestibular, e de 184 a 485HU na medular. CONCLUSÕES: a maior densidade óssea na maxila foi observada entre pré-molares na cortical alveolar vestibular. A tuberosidade maxilar foi a região com menor densidade óssea. A densidade óssea na mandíbula foi maior do que na maxila, e observou-se um acréscimo progressivo de anterior para posterior e de alveolar para basalINTRODUCTION: The cortical thickness, the interradicular spaces width and bone density are the key factors for the efficiency of mini-implants as anchorage resources. OBJECTIVES: The objective was to assess the alveolar and basal bone density in maxilla and mandible in Hounsfield units (HU. METHODS: From eleven files of adults computed tomography images were obtained 660 measurements of bone

  9. The influence of direct laser metal sintering implants on the early stages of osseointegration in diabetic mini-pigs.

    Science.gov (United States)

    Tan, Naiwen; Liu, Xiangwei; Cai, Yanhui; Zhang, Sijia; Jian, Bo; Zhou, Yuchao; Xu, Xiaoru; Ren, Shuai; Wei, Hongbo; Song, Yingliang

    2017-01-01

    High failure rates of oral implants have been reported in diabetic patients due to the disruption of osseointegration. The aim of this study was to investigate whether direct laser metal sintering (DLMS) could improve osseointegration in diabetic animal models. Surface characterizations were carried out on two types of implants. Cell morphology and the osteogenic-related gene expression of MG63 cells were observed under conditions of DLMS and microarc oxidation (MAO). A diabetes model in mini-pigs was established by intravenous injection of streptozotocin (150 mg/kg), and a total of 36 implants were inserted into the mandibular region. Micro-computed tomography (micro-CT) and histologic evaluations were performed 3 and 6 months after implantation. The Ra (the average of the absolute height of all points) of MAO surface was 2.3±0.3 µm while the DLMS surface showed the Ra of 27.4±1.1 µm. The cells on DLMS implants spread out more podia than those on MAO implants through cell morphology analysis. Osteogenic-related gene expression was also dramatically increased in the DLMS group. Obvious improvement was observed in the micro-CT and Van Gieson staining analyses of DLMS implants compared with MAO at 3 months, although this difference disappeared by 6 months. DLMS implants showed a higher bone-implant contact percentage (33.2%±11.2%) at 3 months compared with MAO group (18.9%±7.3%) while similar results were showed at 6 months between DLMS group (42.8%±10.1%) and MAO group (38.3%±10.8%). The three-dimensional environment of implant surfaces with highly porous and fully interconnected channel and pore architectures can improve cell spreading and accelerate the progress of osseointegration in diabetic mini-pigs.

  10. Thermal modeling of a mini rotor-stator system

    NARCIS (Netherlands)

    Dikmen, Emre; Hoogt, van der Peter; Boer, de André; Aarts, Ronald; Jonker, Ben

    2009-01-01

    In this study the temperature increase and heat dissipation in the air gap of a cylindrical mini rotor stator system has been analyzed. A simple thermal model based on lumped parameter thermal networks has been developed. With this model the temperature dependent air properties for the fluid-rotor i

  11. The use of mini-implants in en masse retraction for the treatment of bimaxillary dentoalveolar protrusion

    Science.gov (United States)

    Aljhani, Ali; Zawawi, Khalid H.

    2009-01-01

    This case report describes the treatment of a 22-year-old girl who had incompetent lips with severe bimaxillary dentoalveolar protrusion. The treatment of choice for such patients is usually extraction of four first premolars and retraction of the anterior teeth. To maintain the extraction space, maximum anchorage is required. Mini-implants were used to provide maximum anchorage for obtaining a good facial profile. PMID:24151405

  12. Real Time Imaging of Biomarkers in the Parkinson's Brain Using Mini-Implantable Biosensors. II. Pharmaceutical Therapy with Bromocriptine

    OpenAIRE

    Patricia A. Broderick; Kolodny, Edwin H.

    2009-01-01

    We used Neuromolecular Imaging (NMI) and trademarked BRODERICK PROBE® mini-implantable biosensors, to selectively and separately detect neuro-transmitters in vivo, on line, within seconds in the dorsal striatal brain of the Parkinson’s Disease (PD) animal model. We directly compared our results derived from PD to the normal striatal brain of the non-Parkinson’s Disease (non-PD) animal. This advanced biotechnology enabled the imaging of dopamine (DA), serotonin (5-HT), homovanillic acid (HVA) ...

  13. Real Time Imaging of Biomarkers in the Parkinson's Brain Using Mini-Implantable Biosensors. II. Pharmaceutical Therapy with Bromocriptine

    OpenAIRE

    Patricia A. Broderick; Kolodny, Edwin H.

    2009-01-01

    We used Neuromolecular Imaging (NMI) and trademarked BRODERICK PROBE® mini-implantable biosensors, to selectively and separately detect neurotransmitters in vivo, on line, within seconds in the dorsal striatal brain of the Parkinson’s Disease (PD) animal model. We directly compared our results derived from PD to the normal striatal brain of the non-Parkinson’s Disease (non-PD) animal. This advanced biotechnology enabled the imaging of dopamine (DA), serotonin (5-HT), homovanillic acid (HVA) a...

  14. Geospatial Analysis of Photovoltaic Mini-Grid System Performance

    Directory of Open Access Journals (Sweden)

    Thomas Huld

    2017-02-01

    Full Text Available We present a geographic information system (GIS-based tool for estimating the performance of photovoltaic (PV mini-grid system over large geographical areas. The methodology consists of geospatial analysis and mapping of the energy output and reliability of PV mini-grid system. The algorithm uses a combination of hourly solar radiation data from satellites combined with measured data on PV module and battery performance and estimated electricity consumption data. The methods also make it possible to optimize the PV array and battery storage size for a given location. Results are presented for an area covering Africa and most of Southern and Central Asia. We also investigate the effects of using Li-ion batteries instead of the traditional lead-acid batteries. The use of our spatial analysis as decision support tool could help governments, local authorities and non-governmental organizations to investigate the suitability of PV mini-grids for electrification of regions where access to electricity is lacking. In this way it is possible to identify areas where PV mini-grids are most suitable.

  15. Immediate loading of mandibular overdentures supported by one-piece, direct metal laser sintering mini-implants: a short-term prospective clinical study.

    Science.gov (United States)

    Mangano, Francesco G; Caprioglio, Alberto; Levrini, Luca; Farronato, Davide; Zecca, Piero A; Mangano, Carlo

    2015-02-01

    Only a few studies have dealt with immediately loaded, unsplinted mini-implants supporting ball attachment-retained mandibular overdentures (ODs). The aim of this study is to evaluate treatment outcomes of ball attachment-retained mandibular ODs supported by one-piece, unsplinted, immediately loaded, direct metal laser sintering (DMLS) mini-implants. Over a 4-year period (2009 to 2012), all patients referred to the Dental Clinic, University of Varese, and to a private practice for treatment with mandibular ODs were considered for inclusion in this study. Each patient received three or four DMLS mini-implants. Immediately after implant placement, a mandibular OD was connected to the implants. At each annual follow-up session, clinical and radiographic parameters were assessed, including the following outcome measures: 1) implant failures; 2) peri-implant marginal bone loss; and 3) complications. Statistical analysis was conducted using a life-table analysis. A total of 231 one-piece DMLS mini-implants were inserted in 62 patients. After 4 years of loading, six implants failed, giving an overall cumulative survival rate of 96.9%. The mean distance between the implant shoulder and the first visible bone-to-implant contact was 0.38 ± 0.25 and 0.62 ± 0.20 mm at the 1- and 4-year follow-up examinations, respectively. An incidence of 6.0% of biologic complications was reported; prosthetic complications were more frequent (12.9%). Within the limits of this study, it can be concluded that the immediate loading of one-piece, unsplinted, DMLS titanium mini-implants by means of ball attachment-supported mandibular ODs is a successful treatment procedure. Long-term follow-up studies are needed to confirm these results.

  16. Support for designing waste sorting systems: A mini review.

    Science.gov (United States)

    Rousta, Kamran; Ordoñez, Isabel; Bolton, Kim; Dahlén, Lisa

    2017-08-01

    This article presents a mini review of research aimed at understanding material recovery from municipal solid waste. It focuses on two areas, waste sorting behaviour and collection systems, so that research on the link between these areas could be identified and evaluated. The main results presented and the methods used in the articles are categorised and appraised. The mini review reveals that most of the work that offered design guidelines for waste management systems was based on optimising technical aspects only. In contrast, most of the work that focused on user involvement did not consider developing the technical aspects of the system, but was limited to studies of user behaviour. The only clear consensus among the articles that link user involvement with the technical system is that convenient waste collection infrastructure is crucial for supporting source separation. This mini review reveals that even though the connection between sorting behaviour and technical infrastructure has been explored and described in some articles, there is still a gap when using this knowledge to design waste sorting systems. Future research in this field would benefit from being multidisciplinary and from using complementary methods, so that holistic solutions for material recirculation can be identified. It would be beneficial to actively involve users when developing sorting infrastructures, to be sure to provide a waste management system that will be properly used by them.

  17. Comparison of Anchorage Pattern under Two Types of Orthodontic Mini- Implant Loading During Retraction in Type A Anchorage Cases

    Science.gov (United States)

    Khan, B. Imran; Mandava, Prasad; Reddy, G. Vivek; Nettam, Venkatesh; Bhavikati, Venkat Naidu

    2016-01-01

    Introduction The orthodontic mini-screws are the mainstay of direct skeletal anchorage which requires minimal compliance and provides maximal anchorage control. However, the timing of initiation of orthodontic loading of these mini-screws is not clearly established in the available studies. Aim The purpose of this study was to determine the reciprocal effects on mini-screw implant with immediate loading in comparison to that of delayed loading during retraction. Materials and Methods The prospective clinical study included a sample of 25 orthodontic patients in the age range of 18-25 years. All the cases were of bi-maxillary proclination with Type-A anchorage demands. All the first premolars were indicated for extraction. A split mouth technique for each patient was utilized by loading mini-implant immediately after its placement on one side and the opposite side implant was loaded after a time lag of two weeks post-insertion. Retraction force of 150g was applied for three months on each side. The displacement of the head and tail of the implant, molar anterior tooth retraction was measured on Orthopantomograph (OPG) taken at T1 (initial) and T2 (after three months). A grid method with each 1mm magnified to 500 pixels was superimposed on OPG and the relative displacements were evaluated. Student’s unpaired ‘t’ test was used for comparison between left and right side and paired ‘t’ test for the parameters on the same side. The p-value equal to or less than 0.05 was taken as statistically significant. Results The mean displacement of head of the implant on the immediate loading is 0.57mm where as the tail exhibited 0.75 mm. The head and tail of the implant on the delayed loading displaced by 0.35mm and 0.38mm respectively, on an average when data was analysed. Significant difference between the two types of loading was noted. Conclusion Delayed loading is beneficial as compared to immediate loading during extraction space closure. PMID:27891469

  18. Bone cutting capacity and osseointegration of surface-treated orthodontic mini-implants

    Science.gov (United States)

    Kim, Ho-Young

    2016-01-01

    Objective The objective of the study was to evaluate the practicality and the validity of different surface treatments of self-drilling orthodontic mini-implants (OMIs) by comparing bone cutting capacity and osseointegration. Methods Self-drilling OMIs were surface-treated in three ways: Acid etched (Etched), resorbable blasting media (RBM), partially resorbabla balsting media (Hybrid). We compared the bone cutting capacity by measuring insertion depths into artificial bone (polyurethane foam). To compare osseointegration, OMIs were placed in the tibia of 25 rabbits and the removal torque value was measured at 1, 2, 4, and 8 weeks after placement. The specimens were analyzed by optical microscopy, scanning electron microscopy (SEM), and energy dispersive X-ray spectroscopy (EDS). Results The bone cutting capacity of the etched and hybrid group was lower than the machined (control) group, and was most inhibited in the RBM group (p < 0.05). At 4 weeks, the removal torque in the machined group was significantly decreased (p < 0.05), but was increased in the etched group (p < 0.05). In the hybrid group, the removal torque significantly increased at 2 weeks, and was the highest among all measured values at 8 weeks (p < 0.05). The infiltration of bone-like tissue surface was evaluated by SEM, and calcium and phosphorus were detected via EDS only in the hybrid group. Conclusions Partial RBM surface treatment (hybrid type in this study) produced the most stable self-drilling OMIs, without a corresponding reduction in bone cutting capacity. PMID:27896213

  19. Evaluation of cortical bone thickness of mandible with cone beam computed tomography for orthodontic mini implant installation

    Directory of Open Access Journals (Sweden)

    Seyed Hossein Moslemzade

    2014-07-01

    Full Text Available Background: Achieving maximum anchorage without movement of the teeth in anchorage unit has been a great challenge in orthodontics and the success of the treatment plan highly depends on it. In this case, using orthodontic mini-implants can make a huge difference. The objective of this retrospective study was to measure thickness of cortical bone at prospective mini-implant placement sites in mandible in order to understand stability aspects of mini-implant placement by using cone-beam computed tomography (CBCT images. Materials and Methods: Initial 3-dimensional images of 40 adult patients were studied. The cortical bone thickness was obtained at the alveolar processes from canine to second molar at 5 different vertical levels from the cementoenamel junction (CEJ. To determine the cortical bone thickness, tangent lines were drawn buccolingually to the roots in axial section and a third line was drawn from the middle of these two lines, and the cortical bone thickness was measured where the third line crossed the buccal cortex.   Results: Mandibular and buccal cortical bone thicknesses were 0.79 to 2.49 mm, respectively. There was a statistically significant increase from the CEJ to the apex (P<0.001, while this increase was not statically significant at interdental area of teeth #3 and #4. Comparing the 4 mm section in all sites showed significant increase from anterior to posterior. Conclusion: Based on our results, the cortical bone thickness mostly follows a pattern and depends on the interradicular site rather than individual differences.     Key words: Cone-beam computed tomography; orthodontic anchorage procedures

  20. Quantitative evaluation of maxillary interradicular bone with cone-beam computed tomography for bicortical placement of orthodontic mini-implants.

    Science.gov (United States)

    Yang, Lei; Li, Feifei; Cao, Meng; Chen, Hong; Wang, Xi; Chen, Xuepeng; Yang, Le; Gao, Weiran; Petrone, Joseph F; Ding, Yin

    2015-06-01

    The purpose of this study was to propose a protocol for safe bicortical placement of mini-implants by measuring the interradicular spaces of the maxillary teeth and the bone quality. Cone-beam computed tomography data were obtained from 50 adults. Three-dimensional reconstructions and measurements were made with SimplantPro software (Materialise, Leuven, Belgium). For each interradicular site, the bone thicknesses and interradicular distances at the planes 1.5, 3, 6, and 9 mm above the cementoenamel junction were measured. Standard bone units were defined to evaluate the influences of bone density and the different placement patterns on the stability of the mini-implants. The safe interradicular sites in the maxilla for bicortical placement of 1.5-mm-diameter mini-implants were in all planes between the first and second premolars, and between the second premolar and the first molar. The safe palatal sites were between the first and second molars, and the safe labial sites of the 9-mm plane were between the central incisors, and between the lateral incisor and the canine. The safe buccal sites of the 6- and 9-mm planes were between the first and second molars, and the safe buccal sites of the 3-, 6-, and 9-mm planes were between the canine and the first premolar. Most bone thicknesses were from 8 to 12 mm. The optimal placement angle between the second premolar and the first molar was 58°. Bicortical placement could have more standard bone units than unicortical placement in the maxilla. Bicortical placement would be more stable in the maxilla. For the site between the molars, special care should be taken at a plane higher than 6 mm to prevent maxillary sinus penetration. The most favorable interradicular area in the maxilla was between the second premolar and the first molar. Copyright © 2015 American Association of Orthodontists. Published by Elsevier Inc. All rights reserved.

  1. MiniMAX: miniature, mobile, agile, x-ray system

    Science.gov (United States)

    Watson, Scott A.; Cunningham, Gwynneth; Gonzales, Samuel

    2012-06-01

    We present a unique, lightweight, compact, low-cost, x-ray imager: MiniMAX (Miniature, Mobile, Agile, X-ray). This system, which exploits the best aspects of Computed Radiography (CR) and Digital Radiography (DR) technology, weighs less than 6lbs, fits into a 6" diameter x 16" long carbon-fiber tube, and is constructed almost entirely from offthe- shelf components. MiniMAX is suitable for use in weld inspection, archaeology, homeland security, and veterinary medicine. While quantum limited for MeV radiography, the quantum-efficiency is too low for routine medical use. Formats include: 4"x6", 8"x12", or 16"x24" and can be readily displayed on the camera back, using a pocket projector, or on a tablet computer. In contrast to a conventional, flying-spot scanner, MiniMAX records a photostimulated image from the entire phosphor at once using a bright, red LED flash filtered through an extremely efficient (OD>9) dichroic filter.

  2. The ASTRI/CTA mini-array software system

    Science.gov (United States)

    Tosti, Gino; Schwarz, Joseph; Antonelli, Lucio Angelo; Trifoglio, Massimo; Catalano, Osvaldo; Maccarone, Maria Concetta; Leto, Giuseppe; Gianotti, Fulvio; Canestrari, Rodolfo; Giro, Enrico; Fiorini, Mauro; La Palombara, Nicola; Pareschi, Giovanni; Stringhetti, Luca; Vercellone, Stefano; Conforti, Vito; Tanci, Claudio; Bruno, Pietro; Grillo, Alessandro; Testa, Vincenzo; di Paola, Andrea; Gallozzi, Stefano

    2014-07-01

    ASTRI (Astrofisica con Specchi a Tecnologia Replicante Italiana) is a Flagship Project financed by the Italian Ministry of Education, University and Research, and led by INAF, the Italian National Institute of Astrophysics. The main goals of the ASTRI project are the realization of an end-to-end prototype of a Small Size Telescope (SST) for the Cherenkov Telescope Array (CTA) in a dual- mirror configuration (SST-2M) and, subsequently, of a mini-array comprising seven SST-2M telescopes. The mini-array will be placed at the final CTA Southern Site, which will be part of the CTA seed array, around which the whole CTA observatory will be developed. The Mini-Array Software System (MASS) will provide a comprehensive set of tools to prepare an observing proposal, to perform the observations specified therein (monitoring and controlling all the hardware components of each telescope), to analyze the acquired data online and to store/retrieve all the data products to/from the archive. Here we present the main features of the MASS and its first version, to be tested on the ASTRI SST-2M prototype that will be installed at the INAF observing station located at Serra La Nave on Mount Etna in Sicily.

  3. Treatment of Class II malocclusion with bialveolar protrusion by means of unusual extractions and anchorage mini-implant

    Directory of Open Access Journals (Sweden)

    Jong-Moon Chae

    2012-10-01

    Full Text Available INTRODUCTION: Patients with dental Class II bialveolar protrusion are generally treated by extracting the four first premolars or two first and two second premolars, and retracting the anterior teeth. This case report describes the treatment of an adult patient with bialveolar protrusion, a Class II canine and molar relationship, and lip protrusion. METHODS: In this patient, the maxillary right second molar (1.7 had to be extracted due to extensive caries. To create sufficient space to retract the anterior teeth, the maxillary right posterior teeth were distalized with a maxillary posterior mini-implant (1.2~1.3 mm in diameter, 10 mm long, which was placed into the maxillary tuberosity area and allowed an en masse retraction of the maxillary anterior teeth. RESULTS: Overall, mini-implant can provide anchorage to produce a good facial profile even without additional premolar extraction in cases of dental Class II bialveolar protrusion with the hopeless second molar. CONCLUSION: The total treatment period was 42 months and the results were acceptable for 34 months after debonding.INTRODUÇÃO: os pacientes com Classe II e biprotrusão alveolar são, geralmente, tratados com extração de quatro primeiros pré-molares ou dois primeiros e dois segundos pré-molares, e retração dos dentes anteriores. Este relato de caso descreve o tratamento de um paciente adulto com biprotrusão alveolar, relação de caninos e de molares em Classe II e protrusão labial. MÉTODOS: nesse paciente, o segundo molar superior direito precisou ser extraído devido a cáries extensas. Para criar espaço suficiente para retração dos dentes anteriores, os dentes posterossuperiores direitos foram distalizados com um mini-implante posterossuperior (1,2 ~ 1,3mm de diâmetro, 10mm de comprimento, que foi colocado na área da tuberosidade maxilar e permitiu uma retração em massa dos dentes anteriores. RESULTADOS: em geral, mini-implantes podem fornecer ancoragem para

  4. Mini dental implants for long-term fixed and removable prosthetics: a retrospective analysis of 2514 implants placed over a five-year period.

    Science.gov (United States)

    Shatkin, Todd E; Shatkin, Samuel; Oppenheimer, Benjamin D; Oppenheimer, Adam J

    2007-02-01

    Over the past decade, endosseous implants of increasingly smaller diameters have been introduced into the field of dentistry. Small diameter implants (SDIs) are generally 2.75 mm to 3.3 mm in diameter. They are frequently used in cases of limited alveolar anatomy Mini dental implants (MDIs) are smaller than their SDI counterparts, with diameters ranging from 1.8 mm to 2.4 mm. They are suitable for long-term use-a task for which the device was approved by the Food and Drug Administration. The following study describes the authors' experience with MDIs under this indication. Over a 5-year period, 2514 MDIs were placed in 531 patients. The mean duration of follow-up was 2.9 years. The implants supported fixed (1278) and removable prostheses (1236), with nearly equal placement in the mandible and maxilla (1256 and 1258, respectively). The overall implant survival was 94.2%. Based on a Cox proportional hazards model, statistically significant predictors of failure include use in removable prostheses (hazard ratio = 4.28), the posterior maxilla (3.37), atrophic bone (3.32), and cigarette smokers (2.28). Implant failures (145) were attributed to mobility with or without suppuration (19% vs 81%, respectively). The mean failure time for these implants was approximately 6.4 months (193+/-42 days). This temporally correlates with the osseointegration period. A learning curve was established for this procedure, and implant survival improved with placement experience. Based on these results, the authors have devised treatment guidelines for the use of MDIs in long-term fixed and removable prostheses. MDIs are not a panacea; however, proper training enables the general dentist to successfully implement MDIs into clinical practice.

  5. Audel water well pumps and systems mini-ref

    CERN Document Server

    Woodson, Roger D

    2011-01-01

    Introducing an Audel ""Mini-Ref"" for tradespeople working on water well pumps and pumping systems Water well pumps are used everywhere, with installations numbering in the millions. It's hard to believe that no one has written a small field book that covers these pieces of equipment. Finally, here's a great handy guide is for anyone who needs to know how these pumps work, how to troubleshoot problems unique to this type of piping system, and how to make common repairs for both above ground and submersible pumps. It contains vital and specific references applicable to a wide range of

  6. Eastern Cape hybrid mini-grid systems - a case study

    CSIR Research Space (South Africa)

    Szewczuk, S

    2010-05-01

    Full Text Available -GRID SYSTEMS A CASE STUDY WIND POWER AFRICA 2010 S Szewczuk CSIR May 2010 PRESENTATION OUTLINE • Rationale for Projects • Renewable Energy for Rural Electrification in E Cape • Integrated Energy/Economic Framework • Hybrid mini-grid energy systems... • Impact of research work RATIONALE FOR OFF-GRID PROJECTS • Poverty Reduction: • Sustainable economic and social benefits • Meeting of Millennium Development Goals • Appropriate technology choice: • 500 million African people without access to modern...

  7. Patient’s perception on mini-screws used for molar distalization = Percepção dos pacientes quanto ao uso de mini-implantes para distalização de molares

    Directory of Open Access Journals (Sweden)

    Blaya, Micéli Beck Guimarães

    2010-01-01

    Conclusão: Os mini-implantes foram bem aceitos pelos pacientes e foram eficientes para a distalização de molares quando utilizados em associação com o tratamento ortodôntico para correção da maloclusão de Classe II

  8. Correction of a severe skeletal Class II occlusion with a fixed functional appliance anchored on mini-implants: a patient report.

    Science.gov (United States)

    Gandedkar, Narayan H; Revankar, Ameet V; Ganeshkar, Sanjay V

    2010-01-01

    This report describes the treatment of a patient with a severe skeletal Angle Class II occlusion with a 14-mm overjet, crowding, and protrusion of the mandibular anterior teeth. The Class II relationship was caused mainly by a short corpus of the mandible. A fixed functional appliance was directly anchored on mini-implants, which were inserted in the mandible. A significant amount of mandibular advancement was achieved, with no protrusion of the mandibular anterior teeth. Facial esthetics improved considerably. This is the first patient report to demonstrate that mini-implants can be applied to anchor fixed functional appliances. The rationale to use mini-implants with fixed functional appliances and the potential benefits of this procedure are discussed. © 2010 BY QUINTESSENCE PUBLISHING CO, INC.

  9. REHABILITATION OF PATIENTS WITH PERIODONTALLY-AFFECTED BONE SUPPORT BY THE MINI-INVASIVE APPLICATION OF DENTAL IMPLANTS

    Directory of Open Access Journals (Sweden)

    Diana RADU-GHICA

    2013-03-01

    while, in the posterior one, of –0.14 ± 0.07mm. Conclusions. The osteointegration ratio of the implants inserted in two surgical times, without flaps’ departure (97.92%, is not different from that of osteointegration in cases of their installation with flaps’ departure (98.05%. The secondary stability of the installed implants, without the creation of mucoperiostal flaps, even if insignificant (p > 0.05, exceeds the one of the implants installed by standard methods. Consequently, implants’ osteointegration may be successfully obtained even by their insertion through a mini-invasive method – involving two surgical times, with no departure of the mucoperiostal flaps.

  10. Computer system design description for the spare pump mini-dacs data acquisition and control system

    Energy Technology Data Exchange (ETDEWEB)

    Vargo, G.F. Jr.

    1994-09-29

    The attached document outlines the computer software design for the mini data acquisition and control system (DACS), that supports the testing of the spare pump for Tank 241-SY-101, at the maintenance and storage facility (MASF).

  11. Osseointegration of KrF laser hydroxylapatite films on Ti6A14V alloy by mini-pigs: loaded osseointegration of dental implants

    Science.gov (United States)

    Dostalova, Tatjana; Jelinek, Miroslav; Himmlova, Lucia; Grivas, Christos

    1999-05-01

    Aim of study was to evaluate osseointegration of the KrF laser hydroxyapatite coated titanium alloy Ti6Al4V dental implants. For deposition KrF excimer laser in stainless- steel deposition chamber was used. Thickness of HA films were round 1 μm . Mini-pigs were used in this investigation. Implants were placed vertically into the lower jaw. After 14 weeks unloaded osseointegration the metal ceramic crowns were inserted. the experimental animals were sacrificed (1 year post insertion). The vertical position of implants was controlled with a radiograph. Microscopical sections were cut and ground. Sections were viewed using microscope with CCD camera. 1 year osseointegration in lower jaw confirmed by all implants presence of newly formed bone around the all implants. Laser-deposited coating the layer of fibrous connective tissue was seen only seldom. In the control group (titamium implant without cover) the fibrous connective tissue was seen between implant and newly formed bone.

  12. MiniSAR: a miniature, lightweight, low cost, scalable SAR system

    NARCIS (Netherlands)

    Steeghs, T.P.H.; Halsema, D. van; Hoogeboom, P.

    2001-01-01

    TNO-FEL is developing a miniature, lightweight, low cost, and scalable SAR/MTI system called 'MiniSAR'. The MiniSAR system will be unique in its size and architecture. Initially the demonstrator system will be integrated in a two-seater motorglider platform. Wherever possible,

  13. Laser-treated stainless steel mini-screw implants: 3D surface roughness, bone-implant contact, and fracture resistance analysis.

    Science.gov (United States)

    Kang, He-Kyong; Chu, Tien-Min; Dechow, Paul; Stewart, Kelton; Kyung, Hee-Moon; Liu, Sean Shih-Yao

    2016-04-01

    This study investigated the biomechanical properties and bone-implant intersurface response of machined and laser surface-treated stainless steel (SS) mini-screw implants (MSIs). Forty-eight 1.3mm in diameter and 6mm long SS MSIs were divided into two groups. The control (machined surface) group received no surface treatment; the laser-treated group received Nd-YAG laser surface treatment. Half in each group was used for examining surface roughness (Sa and Sq), surface texture, and facture resistance. The remaining MSIs were placed in the maxilla of six skeletally mature male beagle dogs in a randomized split-mouth design. A pair with the same surface treatment was placed on the same side and immediately loaded with 200 g nickel-titanium coil springs for 8 weeks. After killing, the bone-implant contact (BIC) for each MSI was calculated using micro computed tomography. Analysis of variance model and two-sample t test were used for statistical analysis with a significance level of P laser-treated group compared with the machined group (P Laser treatment increased surface roughness without compromising fracture resistance. Despite increasing surface roughness, laser treatment did not improve BIC. Overall, it appears that medical grade SS has the potential to be substituted for titanium alloy MSIs. © The Author 2015. Published by Oxford University Press on behalf of the European Orthodontic Society. All rights reserved. For permissions, please email: journals.permissions@oup.com.

  14. Choice of Treatment Plan Based on Root Canal Therapy versus Extraction and Implant Placement: A Mini Review.

    Science.gov (United States)

    Parirokh, Masoud; Zarifian, Ahmadreza; Ghoddusi, Jamileh

    2015-01-01

    Case selection and treatment plan are important aspects of endodontic treatment. Dentists should organize the treatment plan based on their knowledge, abilities, skills and more importantly the patients' preference and dentition. Indubitably, the treatment plan for each patient is exclusive and "tailor-made" and cannot be used for all patients. Dentists' selfestimation of their abilities opens up treatment options; however, in difficult or complicated cases it is advisable to refer to a specialist. Currently, one of the most challenging aspects in dentistry is the choice between extraction and placement of implant (EPI) instead of a complicated root canal treatment (RCT). Overemphasis on one treatment plan while neglecting other options, not only mislead the dentist but also impose unnecessary charges to the patients. This mini-review compares RCT to EPI from various aspects to help practitioners in routine decision making.

  15. Development of standardised control and connection systems for mini grid applications

    Energy Technology Data Exchange (ETDEWEB)

    Roberts, D.

    2002-07-01

    Dulas Ltd undertook a project to develop the application of standard grid connection equipment for use by small-scale hydroelectric systems in a mini-grid (or isolated grid) environment. The mini-grid system has greatest potential in developing countries where there is no well-established distribution system. The study was conducted on two small hydro generators which could be connected to form a mini grid with the addition of some generator control and protection equipment and a controllable load system. It was demonstrated that standard control units can be used to connect hydro generators to a mini-grid and maintain the mini-grid system control provided small variations in system frequency can be tolerated. The study was part of the DTI New and Renewable Energy Programme.

  16. The influence of the number and the type of magnetic attachment on the retention of mandibular mini implant overdenture

    Science.gov (United States)

    2017-01-01

    PURPOSE The aim of this study was to compare the retention of mini implant overdenture by the number, the type of magnetic attachment, and the directions of applied dislodging force. MATERIALS AND METHODS The experimental groups were designed by the number and type of magnetic attachment. Twenty samples were tested with Magden implants. Each attachment was composed of the magnet assembly in overdenture sample and the abutment keeper in a mandibular model. Dislodging forces were applied to the overdenture samples (50.0 mm/min) in 3 directions. The loading was repeated 10 times in each direction. The values of dislodging force were analyzed statistically using SPSS at 95% level of confidence. RESULTS The retentive force of group 2 was greater than that of group 1 in both types of attachment in every direction (P < .05). Oblique retentive force of flat type magnetic attachment was higher than that of cushion type attachment in both groups (P < .05). In group 1, oblique retentive force showed the highest and anterior-posterior retentive force showed the lowest value in both attachment types (P < .05). In group 2, both types of attachment showed the lowest retentive force with anteriorposterior direction of dislodging force (P <.05). CONCLUSION Proper retentive properties for implant overdenture were obtained, regardless of the number and type of magnetic attachment. In both types of magnetic attachment, the greater retentive force was attained with more implants. Oblique retentive force of flat type magnetic attachment was greater than that of cushion type. Among all subgroups, anterior-posterior retentive force was the lowest among three different directions of dislodging force. PMID:28243387

  17. Choice of a dental implant system.

    Science.gov (United States)

    Hunt, Peter R; Gartner, Judith L; Norkin, Frederic J

    2005-04-01

    Many dentists are bewildered by the intricacies and complexities of dental implants. They are constantly besieged by product advertisements and can find it difficult to choose which systems to work with. Some dentists are so intimidated by the subject that they choose to avoid getting involved with implants and instead stick to traditional tooth replacement systems. By breaking implants down into 4 main components, the body, collar, connection, and restorative post, it is easier to understand the structure and function of dental implants. Each portion should be designed to achieve certain objectives. Once these structural components are understood, it is easier to compare and contrast differing implant systems.

  18. Data Acquisition and Image Reconstruction Systems from the miniPET Scanners to the CARDIOTOM Camera

    Science.gov (United States)

    Valastván, I.; Imrek, J.; Hegyesi, G.; Molnár, J.; Novák, D.; Bone, D.; Kerek, A.

    2007-11-01

    Nuclear imaging devices play an important role in medical diagnosis as well as drug research. The first and second generation data acquisition systems and the image reconstruction library developed provide a unified hardware and software platform for the miniPET-I, miniPET-II small animal PET scanners and for the CARDIOTOM™.

  19. Deviation between navigated and final 3-dimensional implant position in mini-invasive unicompartmental knee arthroplasty

    Science.gov (United States)

    2012-01-01

    Background and purpose Unicompartmental knee arthroplasty (UKA) is an established method of treating isolated gonartrosis. Modern techniques such as computer-assisted surgery (CAS) and minimally invasive surgery (MIS) are attractive complementary methods to UKA. However, the positioning of the components remains a concern. Thus, we performed a prospective study to assess whether there was deviation between the navigated implant position and the final implant position. Patients and methods We performed UKA with MIS and CAS in 13 patients. By comparing intraoperative navigation data with postoperative computed tomography (CT) measurements, we calculated the deviation between the computer-assisted implant position and the final 3-D implant position of the femoral and tibial components. Results The computer-assisted placement of the femoral and tibial component showed adequate position and consistent results regarding flexion-extension and varus-valgus. However, regarding rotation there was a large variation and 6 of 10 patients were outside the target range for both the femoral component and the tibial component. Interpretation Difficulties in assessing anatomical landmarks with the CAS in combination with MIS might be a reason for the poor rotational alignment of the components. PMID:23043273

  20. The Biolink Implantable Telemetry System

    Science.gov (United States)

    Betancourt-Zamora, Rafael J.

    1999-01-01

    Most biotelemetry applications deal with the moderated data rates of biological signals. Few people have studied the problem of transcutaneous data transmission at the rates required by NASA's Life Sciences-Advanced BioTelemetry System (LS-ABTS). Implanted telemetry eliminate the problems associated with wire breaking the skin, and permits experiments with awake and unrestrained subjects. Our goal is to build a low-power 174-216MHz Radio Frequency (RF) transmitter suitable for short range biosensor and implantable use. The BioLink Implantable Telemetry System (BITS) is composed of three major units: an Analog Data Module (ADM), a Telemetry Transmitter Module (TTM), and a Command Receiver Module (CRM). BioLink incorporates novel low-power techniques to implement a monolithic digital RF transmitter operating at 100kbps, using quadrature phase shift keying (QPSK) modulation in the 174-216MHz ISM band. As the ADM will be specific for each application, we focused on solving the problems associated with a monolithic implementation of the TTM and CRM, and this is the emphasis of this report. A system architecture based on a Frequency-Locked Loop (FLL) Frequency Synthesizer is presented, and a novel differential frequency that eliminates the need for a frequency divider is also shown. A self sizing phase modulation scheme suitable for low power implementation was also developed. A full system-level simulation of the FLL was performed and loop filter parameters were determined. The implantable antenna has been designed, simulated and constructed. An implant package compatible with the ABTS requirements is also being proposed. Extensive work performed at 200MHz in 0.5um complementary metal oxide semiconductors (CMOS) showed the feasibility of integrating the RF transmitter circuits in a single chip. The Hajimiri phase noise model was used to optimize the Voltage Controlled Oscillator (VCO) for minimum power consumption. Two test chips were fabricated in a 0.5pm, 3V CMOS

  1. Assessment of stability of orthodontic mini-implants under orthodontic loading: A computed tomography study

    Directory of Open Access Journals (Sweden)

    Kamlesh Kumar Garg

    2015-01-01

    Conclusion: Miniscrews are a stable anchorage for orthodontic tooth movement but do not remain absolutely stationary like an endosseous implant throughout orthodontic loading although miniscrews might move according to placement site, orthodontic loading, and inflammation of peri-implant tissue. Waiting period between miniscrews placement and orthodontic loading does not significantly affect the miniscrew mobility so immediate loading can be recommended. To prevent hitting any vital organs because of miniscrew mobility, it is recommended that they can be placed in a nontooth-bearing area that has no foramen, major nerves, or blood vessel pathway, or in a tooth-bearing area allowing a 1.5 mm safety clearance between the miniscrew and dental root.

  2. Implant-Prosthetic Rehabilitation in Bilateral Agenesis of Maxillary Lateral Incisors with a Mini Split Crest

    Directory of Open Access Journals (Sweden)

    M. M. Figliuzzi

    2016-01-01

    Full Text Available The reported clinical case describes the surgical procedure of ridge augmentation by using a “split crest” technique with a partial thickness flap and a subsequent implant-prosthetic rehabilitation aimed at treating a bilateral agenesis of the upper lateral incisors. In such cases with vestibule-palatal and mesial-distal scarce bone thicknesses associated with the need of a proper functional and aesthetic rehabilitation, the split crest technique is particularly suitable. In the case we reported, because of the poor bone thicknesses, we performed a minimally invasive split crest which allowed a correct insertion of the fixtures. This technique allowed us to achieve an optimal functional and aesthetic rehabilitation; moreover, we obtained a good emergency profile, ensuring the vitality of the close teeth and ensuring a good primary stability and the following osseointegration of dental implants.

  3. Correction of deep overbite and gummy smile by using a mini-implant with a segmented wire in a growing Class II Division 2 patient.

    Science.gov (United States)

    Kim, Tae-Woo; Kim, Hyewon; Lee, Shin-Jae

    2006-11-01

    A boy, aged 10.5 years, with a Class II molar relationship and a very deep overbite, complaining of a gummy smile and anterior crowding, was treated nonextraction with a mini-implant and Twin-block and edgewise fixed appliances. Severely extruded and retroclined maxillary incisors were intruded and proclined with a nickel-titanium closed-coil spring anchored to a mini-implant and segmented wires; this resolved the gummy smile and deep overbite efficiently without extruding the maxillary molars or opening the mandible. The mandibular incisors were proclined without direct orthodontic force during intrusion of the maxillary incisors; this helped the nonextraction treatment of mandibular incisor crowding. The Twin-block appliance with high-pull headgear promoted mandibular growth, restrained maxillary growth, and changed the canine and molar relationship from Class II to Class I. The patient's overbite and overjet were overtreated, and, 1 year postretention, the patient maintained a good overbite and overjet.

  4. Camouflage of a high-angle skeletal Class II open-bite malocclusion in an adult after mini-implant failure during treatment.

    Science.gov (United States)

    Franzotti Sant'Anna, Eduardo; Carneiro da Cunha, Amanda; Paludo Brunetto, Daniel; Franzotti Sant'Anna, Claudia

    2017-03-01

    The treatment of skeletal anterior open-bite malocclusion requires complex orthodontic planning that considers its multifactorial etiology, treatment limitations, and high relapse rates. This case report illustrates a successful treatment approach for a skeletal high-angle Class II malocclusion in an adult with a severe open bite. The treatment consisted of a high-pull headgear therapy after mini-implants failure during fixed orthodontic therapy. Adequate esthetics and function were achieved. Despite its low probability, the unexpected event of mini-implant loosening during complex treatments should be considered. Therefore, classic orthodontic mechanics should be established, especially when treating patients for whom invasive procedures such as miniplates or orthognathic surgery are not available options.

  5. The MiniPET: a didactic PET system

    Science.gov (United States)

    Pedro, R.; Silva, J.; Gurriana, L.; Silva, J. M.; Maio, A.; Soares Augusto, J.

    2013-03-01

    The MiniPET project aims to design and build a small PET system. It consists of two 4 × 4 matrices of 16 LYSO scintillator crystals and two PMTs with 16 channels resulting in a low cost system with the essential functionality of a clinical PET instrument. It is designed to illustrate the physics of the PET technique and to provide a didactic platform for the training of students and nuclear imaging professionals as well as for scientific outreach. The PET modules can be configured to test for the coincidence of 511 keV gamma rays. The model has a flexible mechanical setup [1] and can simulate 14 diferent ring geometries, from a configuration with as few as 18 detectors per ring (ring radius phi=51 mm), up to a geometry with 70 detectors per ring (phi=200 mm). A second version of the electronic system [2] allowed measurement and recording of the energy deposited in 4 detector channels by photons from a 137Cs radioactive source and by photons resulting of the annihilation of positrons from a 22Na radioactive source. These energy spectra are used for detector performance studies, as well as angular dependency studies. In this paper, the mechanical setup, the front-end high-speed analog electronics, the digital acquisition and control electronics implemented in a FPGA, as well as the data-transfer interface between the FPGA board and a host PC are described. Recent preliminary results obtained with the 4 active channels in the prototype are also presented.

  6. System design description for ``Mini-DACS`` data acquisition and control system

    Energy Technology Data Exchange (ETDEWEB)

    Ermi, A.M.

    1996-10-01

    This document describes the computer software design and associated hardware for the Mini-DACS (Data Acquisition and Control System) in support of testing the second spare pump (HMR-3) for tank 241SY101. The testing of HMR-3 was conducted at the Maintenance and Storage Facility (MASF).

  7. The Role of HCG in Implantation: A Mini-Review of Molecular and Clinical Evidence

    Science.gov (United States)

    Makrigiannakis, Antonis; Vrekoussis, Thomas; Zoumakis, Emmanouel; Kalantaridou, Sophia N.; Jeschke, Udo

    2017-01-01

    Embryo implantation is a complex process involving continuous molecular cross-talk between the embryo and the decidua. One of the key molecules during this process is human chorionic gonadotropin (HCG). HCG effectively modulates several metabolic pathways within the decidua contributing to endometrial receptivity. Herein, a brief overview of the molecular mechanisms regulated by HCG is presented. Furthermore, we summarize the existing evidence regarding the clinical impact on reproductive outcomes after endometrial priming with HCG prior to embryo transfer. Although promising, further evidence is needed to clarify the protocol that would lead to beneficial outcomes. PMID:28629172

  8. Modern power systems product guide: small, mini and micro hydro power (up to 25 MWe)

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    1990-07-01

    The product guide presented gives names and addresses of worldwide manufacturers of small, mini amd micro hydropower plants. Details of turbine type, configuration and performance, power output, generator drive and control system are tabulated. (UK).

  9. Real Time Imaging of Biomarkers in the Parkinson's Brain Using Mini-Implantable Biosensors. II. Pharmaceutical Therapy with Bromocriptine

    Directory of Open Access Journals (Sweden)

    Patricia A. Broderick

    2009-12-01

    Full Text Available We used Neuromolecular Imaging (NMI and trademarked BRODERICK PROBE® mini-implantable biosensors, to selectively and separately detect neurotransmitters in vivo, on line, within seconds in the dorsal striatal brain of the Parkinson’s Disease (PD animal model. We directly compared our results derived from PD to the normal striatal brain of the non-Parkinson’s Disease (non-PD animal. This advanced biotechnology enabled the imaging of dopamine (DA, serotonin (5-HT, homovanillic acid (HVA a metabolite of DA, L-tryptophan (L-TP a precursor to 5-HT and peptides, dynorphin A 1-17 (Dyn A and somatostatin (somatostatin releasing inhibitory factor (SRIF. Each neurotransmitter and neurochemical was imaged at a signature electroactive oxidation/half-wave potential in dorsal striatum of the PD as compared with the non-PD animal. Both endogenous and bromocriptine-treated neurochemical profiles in PD and non-PD were imaged using the same experimental paradigm and detection sensitivities. Results showed that we have found significant neurotransmitter peptide biomarkers in the dorsal striatal brain of endogenous and bromocriptine-treated PD animals. The peptide biomarkers were not imaged in dorsal striatal brain of non-PD animals, either endogenously or bromocriptine-treated. These findings provide new pharmacotherapeutic strategies for PD patients. Thus, our findings are highly applicable to the clinical treatment of PD.

  10. Hybrid coating on a magnesium alloy for minimizing the localized degradation for load-bearing biodegradable mini-implant applications

    Energy Technology Data Exchange (ETDEWEB)

    Kannan, M. Bobby, E-mail: bobby.mathan@jcu.edu.au; Liyanaarachchi, S.

    2013-10-01

    The effect of a hybrid coating, calcium phosphate (CaP) + polylactic acid (PLA), on a magnesium alloy on its in vitro degradation (general and localized) behaviour was studied for potential load-bearing biodegradable mini-implant applications. CaP was coated on a magnesium alloy, AZ91, using an electrochemical deposition method. A spin coating method was used to coat PLA on the CaP coated alloy. In vitro degradation performance of the alloy with hybrid coating was evaluated using electrochemical impedance spectroscopy (EIS) in simulated body fluid (SBF). The EIS results showed that the hybrid coating enhanced the degradation resistance of the alloy by more than two-order of magnitude as compared to the bare alloy and one-order of magnitude higher than that of the CaP coated alloy, after 1 h exposure in simulated body fluid (SBF). Long-term (48 h) EIS results also confirmed that the hybrid coating performed better than the bare alloy and the CaP coated alloy. Importantly, the hybrid coating improved the localized degradation resistance of the alloy significantly, which is critical for better in service mechanical integrity. - Highlights: • A hybrid coating (CaP + PLA) was applied on a magnesium-based alloy. • The hybrid coating enhanced the in vitro degradation resistance of the alloy. • Localized degradation resistance was also improved by the hybrid coating.

  11. Stress distribution in implant-supported prostheses using different connection systems and cantilever lengths: digital photoelasticity.

    Science.gov (United States)

    Goiato, Marcelo Coelho; Shibayama, Ricardo; Gennari Filho, Humberto; de Medeiros, Rodrigo Antonio; Pesqueira, Aldiéris Alves; dos Santos, Daniela Micheline; de Araújo, Cleudmar Amaral

    2016-01-01

    Photoelastic analysis was used to evaluate the biomechanical behaviour of implant-supported, double-screwed crowns with different connection systems and cantilever lengths. Three models were made in PL-2 photoelastic resin and divided into six groups, on the basis of the implant connection system (external hexagon [EH] or Morse taper [MT]), type of abutment (Mini Pilar [Neodent, Curitiba, Paraná, Brazil] or "UCLA") and number of crowns in the cantilever (one or two). The implant-prosthesis unit was placed in a circular polariscope. Occlusal surfaces of the crowns were subjected to 100-N loads in the axial and oblique (45°) directions in a universal testing machine (EMIC). Generated stresses were recorded and analysed qualitatively in a graphics program (Adobe Photoshop). Under axial loading, all of the groups had similar numbers of fringes, which were increased when the crowns were subjected to oblique loading. The highest number of fringes was found during oblique loading in the EH + Mini Pilar group. In conclusion, although the type of implant connection system did not have a direct influence on the stress distribution for axial loading, the cantilever length did have a direct influence on stress distribution. Models with two crowns in the cantilever showed more stress, with a greater concentration of force on the cervical part of the implant.

  12. RAPID MANUFACTURING SYSTEM OF ORTHOPEDIC IMPLANTS

    Science.gov (United States)

    Relvas, Carlos; Reis, Joana; Potes, José Alberto Caeiro; Fonseca, Fernando Manuel Ferreira; Simões, José Antonio Oliveira

    2015-01-01

    This study, aimed the development of a methodology for rapid manufacture of orthopedic implants simultaneously with the surgical intervention, considering two potential applications in the fields of orthopedics: the manufacture of anatomically adapted implants and implants for bone loss replacement. This work innovation consists on the capitation of the in situ geometry of the implant by direct capture of the shape using an elastomeric material (polyvinylsiloxane) which allows fine detail and great accuracy of the geometry. After scanning the elastomeric specimen, the implant is obtained by machining using a CNC milling machine programmed with a dedicated CAD/CAM system. After sterilization, the implant is able to be placed on the patient. The concept was developed using low cost technology and commercially available. The system has been tested in an in vivo hip arthroplasty performed on a sheep. The time increase of surgery was 80 minutes being 40 minutes the time of implant manufacturing. The system developed has been tested and the goals defined of the study achieved enabling the rapid manufacture of an implant in a time period compatible with the surgery time. PMID:27004181

  13. A high-resolution mini-microscope system for wireless real-time monitoring.

    Science.gov (United States)

    Wang, Zongjie; Boddeda, Akash; Parker, Benjamin; Samanipour, Roya; Ghosh, Sanjoy; Menard, Frederic; Kim, Keekyoung

    2017-09-04

    Compact, cost-effective and high-performance microscope that enables the real-time imaging of cells and lab-on-a-chip devices is highly demanded for cell biology and biomedical engineering. This paper aims to present the design and application of an inexpensive wireless mini-microscope with resolution up to 2592 × 1944 pixels and speed up to 90 fps. The mini-microscope system was built on a commercial embedded system (Raspberry Pi). We modified a camera module and adopted an inverse dual lens system to obtain the clear field of view and appropriate magnification for tens of micrometer objects. The system was capable of capturing time-lapse images and transferring image data wirelessly. The entire system can be operated wirelessly and cordlessly in a conventional cell culturing incubator. The developed mini-microscope was used to monitor the attachment and proliferation of NIH-3T3 and HEK 293 cells inside an incubator for 50 hours. In addition, the mini-microscope was used to monitor a droplet generation process in a microfluidic device. The high-quality images captured by the mini-microscope enabled us an automated analysis of experimental parameters. The successful applications prove the great potential of the developed mini-microscope for monitoring various biological samples and microfluidic devices. This paper presents the design of a high resolution mini-microscope system that enables the wireless real-time imaging of cells inside the incubator. This system has been verified to be a useful tool to obtain high-quality images and videos for the automated quantitative analysis of biological samples and lab-on-a-chip devices in the long term.

  14. Bone-to-implant contact after maxillary sinus floor augmentation with Bio-Oss and autogenous bone in different ratios in mini pigs

    DEFF Research Database (Denmark)

    Jensen, Thomas; Schou, Søren; Gundersen, Hans Jørgen Gottlieb

    2013-01-01

    OBJECTIVES: The objective was to test the hypotheses: (i) no differences in bone-to-implant contact formation, and (ii) no differences between the use of autogenous mandibular or iliac bone grafts, when autogenous bone, Bio-Oss mixed with autogenous bone, or Bio-Oss is used as graft...... for the maxillary sinus floor augmentation. MATERIAL AND METHODS: Bilateral sinus floor augmentation was performed in 40 mini pigs with: (A) 100% autogenous bone, (B) 75% autogenous bone and 25% Bio-Oss, (C) 50% autogenous bone and 50% Bio-Oss, (D) 25% autogenous bone and 75% Bio-Oss, or (E) 100% Bio......-Oss. Autogenous bone was harvested from the iliac crest or the mandible and the graft composition was selected at random and placed concomitant with the implant placement. The animals were euthanized 12 weeks after surgery. Bone-to-implant contact was estimated by stereological methods and summarized as median...

  15. Effect of pre-drilling on intraosseous temperature during self-drilling mini-implant placement in a porcine mandible model.

    Science.gov (United States)

    Gurdán, Zsuzsanna; Vajta, László; Tóth, Ákos; Lempel, Edina; Joób-Fancsaly, Árpád; Szalma, József

    2017-03-31

    This in vitro study investigated intraos seous heat production during insertion, with and without pre-drilling, of a self-drilling orthodontic mini-implant. To measure temperature changes and drilling times in pig ribs, a special testing apparatus was used to examine new and worn pre-drills at different speeds. Temperatures were measured during mini-implant placement with and without pre-drilling. The average intraosseous temperature increase during manual mini-implant insertion was similar with and without pre-drilling (11.8 ± 2.1°C vs. 11.3 ± 2.4°C, respectively; P = 0.707). During pre-drilling the mean temperature increase for new drills was 2.1°C at 100 rpm, 2.3°C at 200 rpm, and 7.6°C at 1,200 rpm. Temperature increases were significantly higher for worn drills at the same speeds (2.98°C, 3.0°C, and 12.3°C, respectively), while bone temperatures at 100 and 200 rpm were similar for new and worn drills (P = 0.345 and 0.736, respectively). Baseline bone temperature was approximated within 30 s after drilling in most specimens. Drilling time at 100 rpm was 2.1 ± 0.9 s, but was significantly shorter at 200 rpm (1.1 ± 0.2 s) and 1,200 rpm (0.1 ± 0.03 s). Pre-drilling did not decrease intraosseous temperatures. In patients for whom pre-drilling is indicated, speeds of 100 or 200 rpm are recommended, at least 30 s after pilot drilling.

  16. High performance mini-gas chromatography-flame ionization detector system based on micro gas chromatography column

    Science.gov (United States)

    Zhu, Xiaofeng; Sun, Jianhai; Ning, Zhanwu; Zhang, Yanni; Liu, Jinhua

    2016-04-01

    Monitoring Volatile organic compounds (VOCs) was a very important measure for preventing environmental pollution, therefore, a mini gas chromatography (GC) flame ionization detector (FID) system integrated with a mini H2 generator and a micro GC column was developed for environmental VOC monitoring. In addition, the mini H2 generator was able to make the system explode from far away due to the abandoned use of a high pressure H2 source. The experimental result indicates that the fabricated mini GC FID system demonstrated high repeatability and very good linear response, and was able to rapidly monitor complicated environmental VOC samples.

  17. Design and Performance Evaluation of a UWB Communication and Tracking System for Mini-AERCam

    Science.gov (United States)

    Barton, Richard J.

    2005-01-01

    NASA Johnson Space Center (JSC) is developing a low-volume, low-mass, robotic free-flying camera known as Mini-AERCam (Autonomous Extra-vehicular Robotic Camera) to assist the International Space Station (ISS) operations. Mini-AERCam is designed to provide astronauts and ground control real-time video for camera views of ISS. The system will assist ISS crewmembers and ground personnel to monitor ongoing operations and perform visual inspections of exterior ISS components without requiring extravehicular activity (EAV). Mini-AERCam consists of a great number of subsystems. Many institutions and companies have been involved in the R&D for this project. A Mini-AERCam ground control system has been studied at Texas A&M University [3]. The path planning and control algorithms that direct the motions of Mini-AERCam have been developed through the joint effort of Carnegie Mellon University and the Texas Robotics and Automation Center [5]. NASA JSC has designed a layered control architecture that integrates all functions of Mini-AERCam [8]. The research described in this report is part of a larger effort focused on the communication and tracking subsystem that is designed to perform three major tasks: 1. To transmit commands from ISS to Mini-AERCam for control of robotic camera motions (downlink); 2. To transmit real-time video from Mini-AERCam to ISS for inspections (uplink); 3. To track the position of Mini-AERCam for precise motion control. The ISS propagation environment is unique due to the nature of the ISS structure and multiple RF interference sources [9]. The ISS is composed of various truss segments, solar panels, thermal radiator panels, and modules for laboratories and crew accommodations. A tracking system supplemental to GPS is desirable both to improve accuracy and to eliminate the structural blockage due to the close proximity of the ISS which could at times limit the number of GPS satellites accessible to the Mini-AERCam. Ideally, the tracking system will

  18. Ankylosed maxillary incisor with severe root resorption treated with a single-tooth dento-osseous osteotomy, vertical alveolar distraction osteogenesis, and mini-implant anchorage.

    Science.gov (United States)

    Senışık, Neslihan Ebru; Koçer, Gülperi; Kaya, Bulem Üreyen

    2014-09-01

    Dentoalveolar ankylosis interferes with the vertical growth of the alveolar process, which can lead to an open bite, an unesthetic smile, and occlusal disharmony. This case report presents a new treatment protocol for an ankylosed tooth with severe root resorption using a combined surgical orthodontic management protocol involving a single-tooth dento-osseous osteotomy and vertical alveolar distraction osteogenesis with intraoral elastics and mini-implant anchorage. After distraction and active orthodontic treatment, the patient's anterior open bite was corrected. A Class I dental relationship was achieved, overjet was decreased, and a normal incisor relationship was obtained.

  19. Fluid dynamic design and analysis of a highly loaded Centrifugal rotor for mini orc power systems

    NARCIS (Netherlands)

    Vitale, S.; Pini, M.; Ghidoni, A.; Colonna di Paliano, P.

    2015-01-01

    Organic Rankine Cycle (ORC) power systems are a well-established technology for the conversion of thermal energy sources in the small-to-medium power range. In the last few years, efforts have been devoted to the development of mini ORC (mORC) power systems (5- 30 kWe) for waste heat recovery from t

  20. Fluid dynamic design and analysis of a highly loaded Centrifugal rotor for mini orc power systems

    NARCIS (Netherlands)

    Vitale, S.; Pini, M.; Ghidoni, A.; Colonna di Paliano, P.

    2015-01-01

    Organic Rankine Cycle (ORC) power systems are a well-established technology for the conversion of thermal energy sources in the small-to-medium power range. In the last few years, efforts have been devoted to the development of mini ORC (mORC) power systems (5- 30 kWe) for waste heat recovery from

  1. Development of a multiparticulate system containing enteric-release mini-tablets of omeprazole

    Directory of Open Access Journals (Sweden)

    Volnei Jose Tondo Filho

    2014-09-01

    Full Text Available The main aim of this study was to develop a multiparticulate system containing mini-tablets of omeprazole formulated with an enteric polymer with pH-dependent solubility. Pre-formulation studies showed good flow and compaction capacity, leading to the production ofhigh quality mini-tablets. The mini-tablets were coated in a fluidized bed with hydroxypropylmethylcellulose /Eudragit(r L30D55 and packed into hard gelatin capsules. The dissolution profile showed gastro-resistance and zero-order kinetics. The dissolution profile for the formulation containing lactose as the diluent and coated with 12% (tablet weight gain of polymer was similar to that ofthe reference drug.

  2. A Mini-Electrochemical System with Integrated Micropipet Tip and Pencil Graphite Electrode for Measuring Cytotoxicity.

    Science.gov (United States)

    Wu, Dong-Mei; Guo, Xiao-Ling; Wang, Qian; Li, Jin-Lian; Cui, Ji-Wen; Zhou, Shi; Hao, Su-E

    2017-01-01

    A novel mini-electrochemical system has been developed for evaluating cytotoxicity of anticancer drugs based on trace cell samples. The mini-electrochemical system was integrated by using pencil graphite modified with threonine as working electrode, an Ag/AgCl reference electrode and a micropipet tip as electrochemical cell. The mini-electrochemical system dramatically reduces sample volumes from 500 μL in a traditional electrochemical system to 10 μL, and exhibits excellent electrocatalytic activity toward oxidation of purine from MCF-7 cells due to increased sensitivity provided by threonine. Moreover, the relationship between peak current and the cell concentration in the range from 3.0 × l0(3) to 7.0 × l0(6) cells/mL was studied, and a nonlinear exponential relationship between them was established over a wide concentration range. In evaluating the effect of anticancer drugs on cell viability, the results of drug cytotoxicity test based on cyclophosphamide were in close agreement with classical 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium (MTT) assays. The proposed device is so simple, cheap, and easy to operate that it could be applied to single-use applications. The mini-electrochemical system proved to be a useful tool and can be applied to electrochemical studies of cancer cells as well as other biological samples such as proteins and DNA.

  3. MARGINS mini-lessons: A tour of the Mariana Subduction System (Invited)

    Science.gov (United States)

    Goodliffe, A. M.; Oakley, A.

    2009-12-01

    MARGINS mini-lessons provide an efficient way to quickly move cutting edge MARGINS research into the university classroom. Instructors who are not necessarily familiar with the MARGINS program can easily use mini-lessons in a variety of educational settings. The mini-lesson described herein is centered on bathymetric and multi-channel seismic data collected during a 2003 NSF-MARGINS funded marine geophysical survey in the Mariana Basin. Designed as an approximately sixty minute lecture segment, the lesson covers both the techniques used to collect marine geophysical data and a description of the geology of the system. All geological provinces are included, from the subducting Pacific Plate in the east to the remnant arc in the west. Representative seismic lines and bathymetric images are presented for each province, along with a description of key processes including deformation of the subducting plate, serpentinite mud volcanism, forearc faulting, potentially tsunamigenic landslides, arc volcanism, and backarc spreading. The Mariana subduction system mini-lesson requires a computer with an internet connection, powerpoint, Google Earth, and a web-browser. Questions are embedded in the powerpoint presentation that can be adapted to a specific interactive response system as needed. Optimally the lesson should be used in parallel with a GeoWall. A 3-dimensional ArcScene visualization of the Mariana system is available for download through the MARGINS mini-lessons web site. Such visualizations are particularly effective in helping students understand complex three-dimensional systems. If presented in a computer lab students will benefit from being able to explore the Mariana system using tools such as GeoMapApp.

  4. Genotype by Environment Effects on Potato Mini-Tuber Seed Production in an Aeroponics System

    Directory of Open Access Journals (Sweden)

    Julián F. Mateus-Rodriguez

    2014-11-01

    Full Text Available In order to evaluate the environmental effect on plant development and mini-tuber production of a diverse group of potato genotypes grown under an aeroponic system, a G × E interaction experiment was carried out in greenhouses located at CIP’s experimental stations in La Molina (Lima and Huancayo (Junín. Five contrasting environments were set-up and evaluated. A combined Analysis of Variance was performed for the variables “days to tuber set”, “days to senescence” and “plant height”. An Additive Main Effects and Multiplicative Interaction (AMMI Analysis was performed for yield variables: mini-tuber “weight” and “number of mini-tubers” per plant. There was a high variation in all the responses to the treatments. “Days to tuber set” was influenced by genetic responses, temperature and greenhouse Photosynthetically Active Radiation intensity. Considerable increases in the length of the vegetative cycle and plant height were recorded for all genotypes, and these were particularly notable in the warmer coastal environments. AMMI analysis showed that yield variables were primarily influenced by the genotypic effect followed by the genotype by environment interaction effect. The Venturana variety (T2 was the best performing genotype with a total average mini-tuber “weight” of 644 g per plant while the Chucmarina variety (T1 performed best for the variable “number of mini-tubers” with an overall average of 60.2 mini-tubers per plant. Both showed stability across different environments for these variables. The advanced clones T3 (395434.1, T5 (397077.16 and T6 (397073.16 showed stability for yield variables, but their performance was below the overall average of the trial. It is recommended that the environment and management should ideally be tailored to the genotype as this will result in significant yield gains.

  5. Pembuatan Gigi Tiruan Lengkap Obturator Rahang atas pada Kasus Kelas III Arammany dengan Penguat Mini Dental Implant untuk Protesa Rahang Bawah

    Directory of Open Access Journals (Sweden)

    F. Wihan Pradana

    2011-06-01

    Full Text Available Latar belakang. Kasus Edentulous dengan defek maksilofasial pada geriatri merupakan kasus yang komplek dan menyangkut estetika serta fungsi rongga mulut. Penggunaan hollow bulb dan implant untuk memberikan retensi merupakan alternatif cara yang dapat digunakan dalam perawatan defek maksilofasial dan sisa lingir alveolar yang tipis. Tujuan. dari pembuatan protesa GTL ini ialah untuk mengembalikan fungsi pencernaan rongga mulut sehingga dapat mengembalikan kemampuan mencerna dan mengolah makanan. Pembuatan GTL diupayakan untuk dapat retentif dan stabil sehingga protesa dapat bermanfaat sebagai instrumen rehabilitatif dalam rongga mulut. Kasus. Pasien laki-Iaki usia 70 tahun datang ke klinik prostodonsia FKG UGM dengan keluhan gigi tiruan lengkap yang longgar dan tidak dapat berfungsi dengan baik sehingga makanan dan minuman dapat keluar dari hidung melalui lubang di area palatum yang timbul kurang lebih 2 bulan sebelum datang ke RSGM. Penanganan. Setelah dilakukan proses bedah pengangkatan tumor oleh Onkologis selanjutnya dilakukan perencanaan pembuatan GTL. Paska operasi pasien mengenakan GTL sementara dari GTL lama pasien yang diperbaiki. Proses selanjutnya ialah pembuatan GTL baru untuk mengganti GTL lama yang rusak. Setelah GTL selesai dibuat, dilakukan insersi dan dilanjutkan dengan pemasangan mini dental implant untuk rahang bawah. Satu minggu berikutnya dilakukan pemasangan metal housing implant pada fitting surface gigi tiruan lengkap rahang bawah sehingga implant dan gigi tiruan menjadi satu kesatuan gigi tiruan lengkap  dengan dukungan implant. Kesimpulan. Kontrol2 minggu dan satu bulan menunjukan implant masih stabil dan tidak ada keluhan pada pasien. Pasien dapat menggunakan gigi tiruannya untuk makan dan minum. Dari pemeriksaan subjektif diketanui bahwa dan makanan ataupun minuman tidak lagi keluar melalui hidung pasien.

  6. Use of totally implantable vascular access port with mini-invasive Seldinger technique in 12 dogs undergoing chemotherapy.

    Science.gov (United States)

    Valentini, Fabio; Fassone, Flavia; Pozzebon, Andrea; Gavazza, Alessandra; Lubas, George

    2013-02-01

    Vascular access ports (VPAs) are totally implantable devices designed to provide repeated access to the vascular system. Port access is performed by percutaneous needle insertion using a noncoring needle. VAPs have been placed in 12 dogs affected by different tumors and needing long lasting chemotherapy. Using the non-invasive Seldinger technique a silicone catheter was inserted from the jugular vein up to the junction of the cranial vena cava and the right atrium. The catheter then was connected to the port previously placed in a subcutaneous pocket over the scapula. 7/12 dogs showed no clinical complications. Port was removed in 4/12 dogs for post-operative complications as fistula formation (n.2) and infection/mal-position (n.2). One patient had mild complications shortly after implantation. VPAs were left in site until the death in the rest of patients. VAPs are useful for dogs undergoing long-lasting chemotherapy protocols as these devices allow peripheral veins to be spared and not seriously damaged for repeated infusion of vesicant drugs. In most cases VPAs are well tolerated and may be left in site for several months.

  7. The High-Level Interface Definitions in the ASTRI/CTA Mini Array Software System (MASS)

    Science.gov (United States)

    Conforti, V.; Tosti, G.; Schwarz, J.; Bruno, P.; Cefal‘A, M.; Paola, A. D.; Gianotti, F.; Grillo, A.; Russo, F.; Tanci, C.; Testa, V.; Antonelli, L. A.; Canestrari, R.; Catalano, O.; Fiorini, M.; Gallozzi, S.; Giro, E.; Palombara, N. L.; Leto, G.; Maccarone, M. C.; Pareschi, G.; Stringhetti, L.; Trifoglio, M.; Vercellone, S.; Astri Collaboration; Cta Consortium

    2015-09-01

    ASTRI (Astrofisica con Specchi a Tecnologia Replicante Italiana) is a Flagship Project funded by the Italian Ministry of Education, University and Research, and led by INAF, the Italian National Institute of Astrophysics. Within this framework, INAF is currently developing an end-to-end prototype, named ASTRI SST-2M, of a Small Size Dual-Mirror Telescope for the Cherenkov Telescope Array, CTA. A second goal of the project is the realization of the ASTRI/CTA mini-array, which will be composed of seven SST-2M telescopes placed at the CTA Southern Site. The ASTRI Mini Array Software System (MASS) is designed to support the ASTRI/CTA mini-array operations. MASS is being built on top of the ALMA Common Software (ACS) framework, which provides support for the implementation of distributed data acquisition and control systems, and functionality for log and alarm management, message driven communication and hardware devices management. The first version of the MASS system, which will comply with the CTA requirements and guidelines, will be tested on the ASTRI SST-2M prototype. In this contribution we present the interface definitions of the MASS high level components in charge of the ASTRI SST-2M observation scheduling, telescope control and monitoring, and data taking. Particular emphasis is given to their potential reuse for the ASTRI/CTA mini-array.

  8. Implantable intraocular pressure monitoring systems: Design considerations

    KAUST Repository

    Arsalan, Muhammad

    2013-12-01

    Design considerations and limitations of implantable Intraocular Pressure Monitoring (IOPM) systems are presented in this paper. Detailed comparison with the state of the art is performed to highlight the benefits and challenges of the proposed design. The system-on-chip, presented here, is battery free and harvests energy from incoming RF signals. This low-cost design, in standard CMOS process, does not require any external components or bond wires to function. This paper provides useful insights to the designers of implantable wireless sensors in terms of design choices and associated tradeoffs. © 2013 IEEE.

  9. Implant positioning system using mutual inductance.

    Science.gov (United States)

    Zou, You; O'Driscoll, Stephen

    2012-01-01

    Surgical placement of implantable medical devices (IMDs) has limited precision and post-implantation the device can move over time. Accurate knowledge of the position of IMDs allows better interpretation of data gathered by the devices and may allow wireless power to be focused on the IMD thereby increasing power transfer efficiency. Existing positioning methods require device sizes and/or power consumptions which exceed the limits of in-vivo mm-sized IMDs applications. This paper describes a novel implant positioning system which replaces the external transmitting (TX) coil of a wireless power transfer link by an array of smaller coils, measures the mutual inductance between each coil in the TX array and the implanted receiving (RX) coil, and uses the spatial variation in those mutual inductances to estimate the location of the implanted device. This method does not increase the hardware or power consumption in the IMD. Mathematical analysis and electromagnetic simulations are presented which explain the theory underlying this scheme and show its feasibility. A particle swarm based algorithm is used to estimate the position of the RX coil from the measured mutual inductance values. MATLAB simulations show the positioning estimation accuracy on the order of 1 mm.

  10. Experimental and computational determination of the hydrodynamics of mini vessel dissolution testing systems.

    Science.gov (United States)

    Wang, Bing; Armenante, Piero M

    2016-08-20

    Mini vessel dissolution testing systems consist of a small-scale 100-mL vessel with a small paddle impeller, similar to the USP Apparatus 2, and are typically utilized when only small amounts of drug product are available during drug development. Despite their common industrial use, mini vessels have received little attention in the literature. Here, Computational Fluid Dynamics (CFD) was used to predict velocity profiles, flow patterns, and strain rate distribution in a mini vessel at different agitation speeds. These results were compared with experimental velocity measurements obtained with Particle Image Velocimetry (PIV). Substantial agreement was observed between CFD results and PIV data. The flow is strongly dominated by the tangential velocity component. Secondary flows consist of vertical upper and lower recirculation loops above and below the impeller. A low recirculation zone was observed in the lower part of the vessel. The radial and axial velocities in the region just below the impeller are very small especially in the innermost core zone below the paddle, where tablet dissolution occurs. Increasing agitation speed reduces the radius of this zone, which is always present at any speed, and only modestly increases the tangential flow intensity, with significant implication for dissolution testing in mini vessels.

  11. Electrochemical behavior of dental implant system before andafter clinical use

    Institute of Scientific and Technical Information of China (English)

    Chae-Heon CHUNG; Hee-Jung KIM; Yong-Tae JEONG; Mee-Kyoung SON; Yong-Hoon JEONG; Han-Cheol CHOE

    2009-01-01

    Electrochemical behavior of dental implant system before and after clinical use (in vivo and in vitro) was researched by using abutment and titanium fixture. To simulate an oral environment, the samples of clinically used and non-used implant systems as a working electrode were exposed to artificial saliva at (36.5±1) ℃. Electrochemical tests were carried out using a potentiostat. After electrochemical test, the corrosion morphology of each sample was investigated by FE-SEM and EDS. The corrosion potential and pitting potential of clinically used implant system are lower than those of non-used implant system, and clinically used implant system exhibits a lower range of passivation, indicating a less degree of inherent resistance against chloride ion. The polarization resistance decreases in the case of clinically used implant system, whereas, Rp for clinically non-used implant system increases compared with clinically used implant system.

  12. Design of mini-multi-gas monitoring system based on IR absorption

    Science.gov (United States)

    Tan, Qiu-lin; Zhang, Wen-dong; Xue, Chen-yang; Xiong, Ji-jun; Ma, You-chun; Wen, Fen

    2008-07-01

    In this paper, a novel non-dispersive infrared ray (IR) gas detection system is described. Conventional devices typically include several primary components: a broadband source (usually an incandescent filament), a rotating chopper shutter, a narrow-band filter, a sample tube and a detector. But we mainly use the mini-multi-channel detector, electrical modulation means and mini-gas-cell structure. To solve the problems of gas accidents in coal mines, and for family safety that results from using gas, this new IR detection system with integration, miniaturization and non-moving parts has been developed. It is based on the principle that certain gases absorb infrared radiation at specific (and often unique) wavelengths. The infrared detection optics principle used in developing this system is mainly analyzed. The idea of multi-gas detection is introduced and guided through the analysis of the single-gas detection. Through researching the design of cell structure, a cell with integration and miniaturization has been devised. By taking a single-chip microcomputer (SCM) as intelligence handling, the functional block diagram of a gas detection system is designed with the analyzing and devising of its hardware and software system. The way of data transmission on a controller area network (CAN) bus and wireless data transmission mode is explained. This system has reached the technology requirement of lower power consumption, mini-volume, wide measure range, and is able to realize multi-gas detection.

  13. Systemic alendronate treatment improves fixation of press-fit implants: a canine study using nonloaded implants

    DEFF Research Database (Denmark)

    Jensen, Thomas B; Bechtold, Joan E; Chen, Xinqian

    2007-01-01

    of alendronate treatment. Bone ongrowth (bone in contact with implant surface) was estimated using the linear intercept technique and shear strength was calculated as the slope on a load-displacement curve. For the press fit implants, alendronate treatment significantly increased bone ongrowth from 24% to 29...... early implant stability is an important predictor of longevity, systemic alendronate treatment could be an important clinical tool to positively influence the early stages of implant incorporation. Udgivelsesdato: 2007-Jun...

  14. Mini drug pump for ophthalmic use.

    Science.gov (United States)

    Saati, Saloomeh; Lo, Ronalee; Li, Po-Ying; Meng, Ellis; Varma, Rohit; Humayun, Mark S

    2010-03-01

    To evaluate the feasibility of developing a novel mini drug pump for ophthalmic use. Using principles of microelectromechanical systems engineering, a mini drug pump was fabricated. The pumping mechanism is based on electrolysis and the pump includes a drug refill port as well as a check valve to control drug delivery. Drug pumps were tested first on the bench-top and then after implantation in rabbits. For the latter, we implanted 4 elliptical (9.9 x 7.7 x 1.8 mm) non-electrically active pumps into 4 rabbits. The procedure is similar to implantation of a glaucoma aqueous drainage device. To determine the ability to refill and also the patency of the cannula, at intervals of 4-6 weeks after implantation, we accessed the drug reservoir with a transconjunctival needle and delivered approximately as low as 1 microL of trypan blue solution (0.06%) into the anterior chamber. Animals were followed by slit lamp examination, photography, and fluorescein angiography. Bench-top testing showed 2.0 microL/min delivery when using 0.4 mW of power for electrolysis. One-way valves showed reliable opening pressures of 470 mmHg. All implanted devices refilled at 4-6 weeks intervals for 4-6 months. No infection was seen. No devices extruded. No filtering bleb formed over the implant. A prototype ocular mini drug pump was built, implanted, and refilled. Such a platform needs more testing to determine the long term biocompatibility of an electrically-controlled implanted pump. Testing with various pharmacological agents is needed to determine its ultimate potential for ophthalmic use.

  15. Workshop Goals: Mini-workshop on RHIC Rf system

    Energy Technology Data Exchange (ETDEWEB)

    Hahn, H. [Brookhaven National Lab. (BNL), Upton, NY (United States)

    1988-07-11

    The objectives of this study are to: review rf system requirements; review cavity and amplifier hardware; establish basis for revised CDR text and cost estimate; and provide a written summary and technical notes.

  16. Mini Solar and Sea Current Power Generation System

    Science.gov (United States)

    Almenhali, Abdulrahman; Alshamsi, Hatem; Aljunaibi, Yaser; Almussabi, Dheyab; Alshehhi, Ahmed; Hilal, Hassan Bu

    2017-07-01

    The power demand in United Arab Emirates is increased so that there is a consistent power cut in our region. This is because of high power consumption by factories and also due to less availability of conventional energy resources. Electricity is most needed facility for the human being. All the conventional energy resources are depleting day by day. So we have to shift from conventional to non-conventional energy resources. In this the combination of two energy resources is takes place i.e. wind and solar energy. This process reviles the sustainable energy resources without damaging the nature. We can give uninterrupted power by using hybrid energy system. Basically this system involves the integration of two energy system that will give continuous power. Solar panels are used for converting solar energy and wind turbines are used for converting wind energy into electricity. This electrical power can utilize for various purpose. Generation of electricity will be takes place at affordable cost. This paper deals with the generation of electricity by using two sources combine which leads to generate electricity with affordable cost without damaging the nature balance. The purpose of this project was to design a portable and low cost power system that combines both sea current electric turbine and solar electric technologies. This system will be designed in efforts to develop a power solution for remote locations or use it as another source of green power.

  17. Effects of Dental Implant-abutment Interfaces on the Reliability of Implant Systems

    Directory of Open Access Journals (Sweden)

    Zhang Xiao

    2016-01-01

    Full Text Available In this paper, by analyzing the effects of two different kinds of implant-abutment connection interfaces under the same working condition on the mechanical and fatigue performances of the implant system as well as on the surrounding bones, we intend to study such effects on the reliability of the implants and provide a theoretical basis for the design and clinical application of dental implant systems. For the purpose, we adopt a 3-D modeling method to establish the model, and use FEA (finite element analysis to carry out static mechanic and fatigue analysis on the implant system and its surrounding bones; then we make the two implant systems, and carry out fatigue tests on a dynamic fatigue testing machine to verify the FEA results. After comparing the results from the two different systems, we find that the stress distribution and fatigue safety factor of the system which has deeper axial matching of the taper connection are better than those of the other system, that is to say, between the two major elements of a implant system, the axial length of the connecting taper and the size of the hexagon, the former has greater effects than the latter. When the axial matching is deeper, the stress distribution of the implant system will be better, the fatigue safety factor will be higher, and the implant system will be more reliable.

  18. CLINICAL CONSIDERATIONS OF DENTAL IMPLANT SYSTEM IN IMMEDIATE LOADING IMPLANT CASES

    Directory of Open Access Journals (Sweden)

    Carolina Damayanti Marpaung

    2015-06-01

    Full Text Available Immediate loading of dental implant has been researched intensively in the development of Branemark’s early concept of 2 stages implant placement. This was embarked from both patients and practiitioner’s convenience towards a simpler protocol and shorter time frame. Many recent researchers later found that micromotions derived from occlusal loading for a certain degree, instead of resulting a fibrous tissue encapsulation, can enhance the osseointegration process. Dental Implant system enhancement towards maximizing the primary stability held a key factor in Branemark’s concept development. Surgical protocol and implant design was found to give a significant contribution to the prognosis of immediate-loading implants.

  19. [Design and application of implantable medical device information management system].

    Science.gov (United States)

    Cao, Shaoping; Yin, Chunguang; Zhao, Zhenying

    2013-03-01

    Through the establishment of implantable medical device information management system, with the aid of the regional joint sharing of resources, we further enhance the implantable medical device traceability management level, strengthen quality management, control of medical risk.

  20. Development of a mini-mobile digital radiography system by using wireless smart devices.

    Science.gov (United States)

    Jeong, Chang-Won; Joo, Su-Chong; Ryu, Jong-Hyun; Lee, Jinseok; Kim, Kyong-Woo; Yoon, Kwon-Ha

    2014-08-01

    The current technologies that trend in digital radiology (DR) are toward systems using portable smart mobile as patient-centered care. We aimed to develop a mini-mobile DR system by using smart devices for wireless connection into medical information systems. We developed a mini-mobile DR system consisting of an X-ray source and a Complementary Metal-Oxide Semiconductor (CMOS) sensor based on a flat panel detector for small-field diagnostics in patients. It is used instead of the systems that are difficult to perform with a fixed traditional device. We also designed a method for embedded systems in the development of portable DR systems. The external interface used the fast and stable IEEE 802.11n wireless protocol, and we adapted the device for connections with Picture Archiving and Communication System (PACS) and smart devices. The smart device could display images on an external monitor other than the monitor in the DR system. The communication modules, main control board, and external interface supporting smart devices were implemented. Further, a smart viewer based on the external interface was developed to display image files on various smart devices. In addition, the advantage of operators is to reduce radiation dose when using remote smart devices. It is integrated with smart devices that can provide X-ray imaging services anywhere. With this technology, it can permit image observation on a smart device from a remote location by connecting to the external interface. We evaluated the response time of the mini-mobile DR system to compare to mobile PACS. The experimental results show that our system outperforms conventional mobile PACS in this regard.

  1. Characterization of a mini-channel heat exchanger for a heat pump system

    Science.gov (United States)

    Arteconi, A.; Giuliani, G.; Tartuferi, M.; Polonara, F.

    2014-04-01

    In this paper a mini-channel aluminum heat exchanger used in a reversible heat pump is presented. Mini-channel finned heat exchangers are getting more and more interest for refrigeration systems, especially when compactness and low refrigerant charge are desired. Purpose of this paper was to characterize the mini-channel heat exchanger used as evaporator in terms of heat transfer performance and to study the refrigerant distribution in the manifold. The heat exchanger characterization was performed experimentally by means of a test rig built up for this purpose. It is composed of an air-to-air heat pump, air channels for the external and internal air circulation arranged in a closed loop, measurement sensors and an acquisition system. The overall heat transfer capacity was assessed. Moreover, in order to characterize the flow field of the refrigerant in the manifold of the heat exchanger, a numerical investigation of the fluid flow by means of CFD was performed. It was meant to evaluate the goodness of the present design and to identify possible solutions for the future improvement of the manifold design.

  2. Mini-Warriors: Microelectromechanical Systems: A Munitions Revolution

    Science.gov (United States)

    2014-02-01

    typically contains $1,000 worth of conventional accelerometers and gyroscopes . An equivalent MEMS device, costing $20, can be directly substituted in...accelerometers and gyroscopes . An equivalent MEMS device, costing $20, can be directly substituted in this platform. This represents a 50x subsystem cost reduction.” ...or MEMS , are increasingly found in systems we use daily, replacing larger, heavier, and less reliable components at lower costs. They are freeing

  3. Mini-scleral Contact Lens for Management of Poor Visual Outcomes after Intrastromal Corneal Ring Segments Implantation in Keratoconus

    Science.gov (United States)

    Alipour, Fatemeh; Rahimi, Firoozeh; Hashemian, Mohammad Naser; Ajdarkosh, Zahra; Roohipoor, Ramak; Mohebi, Masoumeh

    2016-01-01

    Purpose: To evaluate the feasibility and efficacy of mini-scleral design (MSD) contact lenses to treat keratoconus patients who were unsatisfied with the results of corneal inlay. Methods: In this prospective interventional case series, 9 eyes of 6 keratoconus patients who were unsatisfied with the results of corneal inlay were fitted with MSD contact lenses. Demographic data, uncorrected visual acuity (UCVA), best spectacle-corrected visual acuity (BSCVA), and higher order aberrations (HOAs) were evaluated before contact lens fitting. Corrected visual acuity by placing the MSD contact lens with or without over-refraction, and HOAs were measured one hour after contact lens fitting. One month after contact lens wearing, corrected visual acuity by placing the MSD contact lens with over-refraction and possible contact lens related problems were assessed. Ocular comfort and contact lens handling problems were asked in follow-up visits. The data was analyzed using descriptive statistical tests. Results: Nine eyes of 6 patients were successfully fitted with the mini-scleral lens. Fitting was ideal in 7 eyes and acceptable in 2 eyes. Mean corrected visual acuity by placing the MSD lens without over-refraction was 0.09 (range, 0.00-0.15) LogMAR which was significantly better than the mean BSCVA of 0.38 (range, 0.2-0.6) LogMAR (P = 0.007). The mean root mean square (RMS) of third-order coma and trefoil significantly decreased after MSD contact lens fitting (P = 0.012 and P = 0.015, respectively); however, changes in the fourth-order spherical aberration were not statistically significant (P = 0.336). Conclusion: Mini-scleral contact lenses may be helpful in the management of visually unsatisfied patients after corneal inlay. PMID:27621780

  4. Mini gamma camera, camera system and method of use

    Science.gov (United States)

    Majewski, Stanislaw; Weisenberger, Andrew G.; Wojcik, Randolph F.

    2001-01-01

    A gamma camera comprising essentially and in order from the front outer or gamma ray impinging surface: 1) a collimator, 2) a scintillator layer, 3) a light guide, 4) an array of position sensitive, high resolution photomultiplier tubes, and 5) printed circuitry for receipt of the output of the photomultipliers. There is also described, a system wherein the output supplied by the high resolution, position sensitive photomultipiler tubes is communicated to: a) a digitizer and b) a computer where it is processed using advanced image processing techniques and a specific algorithm to calculate the center of gravity of any abnormality observed during imaging, and c) optional image display and telecommunications ports.

  5. Vertical osteoconductivity of sputtered hydroxyapatite-coated mini titanium implants after dura mater elevation: Rabbit calvarial model.

    Science.gov (United States)

    Wang, Xin; Zakaria, Osama; Madi, Marwa; Kasugai, Shohei

    2015-01-01

    This study evaluated the quantity and quality of newly formed vertical bone induced by sputtered hydroxyapatite-coated titanium implants compared with sandblasted acid-etched implants after dura mater elevation. Hydroxyapatite-coated and non-coated implants (n = 20/group) were used and divided equally into two groups. All implants were randomly placed into rabbit calvarial bone (four implants for each animal) emerging from the inferior cortical layer, displacing the dura mater 3 mm below the original bone. Animals were sacrificed at 4 (n = 5) and 8 (n = 5) weeks post-surgery. Vertical bone height and area were analyzed histologically and radiographically below the original bone. Vertical bone formation was observed in both groups. At 4 and 8 weeks, vertical bone height reached a significantly higher level in the hydroxyapatite compared with the non-coated group (p Vertical bone area was significantly larger in the hydroxyapatite compared with the non-coated group at 4 and 8 weeks (p vertical bone formation can be induced by dura mater elevation and sputtered hydroxyapatite coating can enhance vertical bone formation.

  6. Perioperative Systemic Inflammatory Response following Robot-Assisted Laparoscopic Cystectomy vs. Open Mini-Laparotomy Cystectomy

    DEFF Research Database (Denmark)

    Skjold Kingo, Pernille; Palmfeldt, Johan; Nørregaard, Rikke

    2017-01-01

    INTRODUCTION: Surgeries, such as radical cystectomy (RC), induce a systemic inflammatory response (SIR). SIR plays an important role in controlling the human immune system. This study aims at comparing the SIR in robot-assisted laparoscopic cystectomy (RALC) to open mini-laparotomy cystectomy (OMC...... with intracorporeal UD (RALC-IUD; n = 9) was performed. Blood samples were obtained preoperatively (PREOP), immediately after surgery (POD0), 24 (POD1) and 48 h (POD2) postoperatively. Clinical parameters were collected from medical records. RESULTS: Estimated blood loss and blood transfusion volume was higher in OMC...

  7. Measurement of volatilized mercury by a mini-system: a simple, reliable and reproducible technique

    Directory of Open Access Journals (Sweden)

    Cursino Luciana

    2003-01-01

    Full Text Available A simple and easy new technique for volatilized mercury determination in biological systems was developed. This technique is fast and sensitive and can overcome the problems that arise due to the extremely low readings during the measurements and reproducibility in biological material (bacteria. It measures directly the volatilized metallic mercury of bacteria by means of a chemical adsorbent in a coupled mini-system, as a modified technique for mercury in air analysis. It is potentially of interest to the bioremediation and bacterial mercury resistance communities

  8. Bacterial Leakage and Microgap along Implant-Abutment Connection in Three Different Implant Systems

    Directory of Open Access Journals (Sweden)

    Farshad Bajoghli

    2016-11-01

    Full Text Available A microgap between implant and abutment connection can act as a bacterial source and cause inflammation, even endanger Osseointegration and subsequently change clinical and histological parameters. The goal of this study was to evaluate the microgap and microbial leakage of implant-abutment connection in three different implant systems. In this experimental study, 28 implants in 3 groups (10 Zimmer with conical connection of 8 degrees, 10 Dentium with conical connection of 11 degrees, 8 Test implants with conical connection of 16 degrees were used. Microleakage of Escherichia coli was assessed at intervals of 5, 24, 48 hours and 2 weeks. Microgap was measured at 4 random points by scanning electron microscope. Data were analysed by Spss version 22 and kruskal-Wallis, Mann-Whitney, Chi- square, Kaplan- Meier tests. (α=0.5 Mean microgap was 4.8μm (±2.2 in Zimmer group, 3.1μm (±1.4 in Implantium group and 16.9μm (±8.7 in test group. After 2 weeks from start of the study, 20 percent of Zimmer and Dentium implants and 25 percent of test implant showed microleakage. Microleakage between Zimmer and Dentium implants was not significant; however, there was a significant difference between test implant and other groups. Microbial leakage was observed in all three implant systems. Although; there were differences in microgap between three groups, Microbial leakage was not statistically significant.

  9. CLINICAL CONSIDERATIONS OF DENTAL IMPLANT SYSTEM IN IMMEDIATE LOADING IMPLANT CASES

    OpenAIRE

    2015-01-01

    Immediate loading of dental implant has been researched intensively in the development of Branemark’s early concept of 2 stages implant placement. This was embarked from both patients and practiitioner’s convenience towards a simpler protocol and shorter time frame. Many recent researchers later found that micromotions derived from occlusal loading for a certain degree, instead of resulting a fibrous tissue encapsulation, can enhance the osseointegration process. Dental Implant system enhance...

  10. The Mini-Balance Evaluation Systems Test (Mini-BESTest) Demonstrates Higher Accuracy in Identifying Older Adult Participants With History of Falls Than Do the BESTest, Berg Balance Scale, or Timed Up and Go Test.

    Science.gov (United States)

    Yingyongyudha, Anyamanee; Saengsirisuwan, Vitoon; Panichaporn, Wanvisa; Boonsinsukh, Rumpa

    2016-01-01

    Balance deficits a significant predictor of falls in older adults. The Balance Evaluation Systems Test (BESTest) and the Mini-Balance Evaluation Systems Test (Mini-BESTest) are tools that may predict the likelihood of a fall, but their capabilities and accuracies have not been adequately addressed. Therefore, this study aimed at examining the capabilities of the BESTest and Mini-BESTest for identifying older adult with history of falls and comparing the participants with history of falls identification accuracy of the BESTest, Mini-BESTest, Berg Balance Scale (BBS), and the Timed Up and Go Test (TUG) for identifying participants with a history of falls. Two hundred healthy older adults with a mean age of 70 years were classified into participants with and without history of fall groups on the basis of their 12-month fall history. Their balance abilities were assessed using the BESTest, Mini-BESTest, BBS, and TUG. An analysis of the resulting receiver operating characteristic curves was performed to calculate the area under the curve (AUC), sensitivity, specificity, cutoff score, and posttest accuracy of each. The Mini-BESTest showed the highest AUC (0.84) compared with the BESTest (0.74), BBS (0.69), and TUG (0.35), suggesting that the Mini-BESTest had the highest accuracy in identifying older adult with history of falls. At the cutoff score of 16 (out of 28), the Mini-BESTest demonstrated a posttest accuracy of 85% with a sensitivity of 85% and specificity of 75%. The Mini-BESTest had the highest posttest accuracy, with the others having results of 76% (BESTest), 60% (BBS), and 65% (TUG). The Mini-BESTest is the most accurate tool for identifying older adult with history of falls compared with the BESTest, BBS, and TUG.

  11. A control system of a mini survey facility for photometric monitoring

    Science.gov (United States)

    Tsutsui, Hironori; Yanagisawa, Kenshi; Izumiura, Hideyuki; Shimizu, Yasuhiro; Hanaue, Takumi; Ita, Yoshifusa; Ichikawa, Takashi; Komiyama, Takahiro

    2016-08-01

    We have built a control system for a mini survey facility dedicated to photometric monitoring of nearby bright (Kdome and a small (30-mm aperture) wide-field (5 × 5 sq. deg. field of view) infrared (1.0-2.5 microns) camera on an equatorial fork mount, as well as power sources and other associated equipment. All the components other than the camera are controlled by microcomputerbased I/O boards that were developed in-house and are in many of the open-use instruments in our observatory. We present the specifications and configuration of the facility hardware, as well as the structure of its control software.

  12. Genotype by Environment Effects on Potato Mini-Tuber Seed Production in an Aeroponics System

    OpenAIRE

    Julián F. Mateus-Rodriguez; Stef de Haan; Alfredo Rodríguez-Delfín

    2014-01-01

    In order to evaluate the environmental effect on plant development and mini-tuber production of a diverse group of potato genotypes grown under an aeroponic system, a G × E interaction experiment was carried out in greenhouses located at CIP’s experimental stations in La Molina (Lima) and Huancayo (Junín). Five contrasting environments were set-up and evaluated. A combined Analysis of Variance was performed for the variables “days to tuber set”, “days to senescence” and “plant height”. An Ad...

  13. Distalization of maxillary arch and correction of Class II with mini-implants: A report of two cases

    Directory of Open Access Journals (Sweden)

    Pawankumar Dnyandeo Tekale

    2015-01-01

    Full Text Available This article reports the successful use of mini-screws in the maxilla to treat two patients of age 21-year and 17-year-old girls. Both the patients had a skeletal Class II malocclusion with protrusive maxillary teeth and angels Class II mal-occlusion. Temporary anchorage devices (TADs in the posterior dental region between maxillary second premolar and maxillary first molar teeth on both sides were used as anchorage for the retraction and intrusion of her maxillary anterior teeth. Those appliances, combined with a compensatory curved maxillary archwire, eliminated spacing, deep bite, forwardly placed and proclined upper front teeth and the protrusive profile, corrected the molar relationship from Class II to Class I. With no extra TADs in the anterior region for intrusion, the treatment was workable and simple. The patient received a satisfactory occlusion and an attractive smile. This technique requires minimal compliance and is particularly useful for correcting Class II patients with protrusive maxillary front teeth and dental deep bite.

  14. a Mini Multi-Gas Detection System Based on Infrared Principle

    Science.gov (United States)

    Zhijian, Xie; Qiulin, Tan

    2006-12-01

    To counter the problems of gas accidents in coal mines, family safety resulted from using gas, a new infrared detection system with integration and miniaturization has been developed. The infrared detection optics principle used in developing this system is mainly analyzed. The idea that multi gas detection is introduced and guided through analyzing single gas detection is got across. Through researching the design of cell structure, the cell with integration and miniaturization has been devised. The way of data transmission on Controller Area Network (CAN) bus is explained. By taking Single-Chip Microcomputer (SCM) as intelligence handling, the functional block diagram of gas detection system is designed with its hardware and software system analyzed and devised. This system designed has reached the technology requirement of lower power consumption, mini-volume, big measure range, and able to realize multi-gas detection.

  15. REFINED MODEL OF THE OPTICAL SYSTEM FOR SPACE MINI-VEHICLES WITH LASER PROPULSION

    Directory of Open Access Journals (Sweden)

    M. S. Egorov

    2015-09-01

    Full Text Available Simulation results for on-board optical system of a space mini-vehicle with laser propulsion are presented. This system gives the possibility for receiving theremote laser radiation power independently of a system telescope mutual orientation to the vehicle orbiting direction. The on-board optical system is designed with the use of such optical elements as optical hinges and turrets. The system incorporates the optical switch that is a special optical system adapting optically both receiving telescope and laser propulsion engines. Modeling and numerical simulation of the system have been performed with the use of ZEMAX software (Radiant Ltd. The object matter of calculations lied in size definition of system optical elements, requirements to accuracy of their manufacturing and reciprocal adjusting to achieve an efficient radiation energy delivery to laser propulsion engine. Calculations have been performed with account to the limitations on the mini-vehicle mass, its overall dimensions, and radiation threshold density of the optical elements utilized. The requirements to the laser beam quality at the entrance aperture of laser propulsion engine have been considered too. State-of-the-art optical technologies make it possible to manufacture space reflectors made of CO-115M glassceramics with weight-reducing coefficient of 0.72 and the radiation threshold of 5 J/cm2 for the radiation with a 1.064 microns wavelength at 10-20 ns pulse duration. The optimal diameter of a receiving telescope primary mirror has been 0.5 m when a coordinated transmitting telescope diameter is equal to 1 m. This provides the reception of at least 84% of laser energy. The main losses of radiation energy are caused by improper installation of receiving telescope mirrors and by in-process errors arising at manufacturing the telescope mirrors with a parabolic surface. It is shown that requirements to the in-process admissible errors for the on-board optical system elements

  16. Integrating Low-Cost Mems Accelerometer Mini-Arrays (mama) in Earthquake Early Warning Systems

    Science.gov (United States)

    Nof, R. N.; Chung, A. I.; Rademacher, H.; Allen, R. M.

    2016-12-01

    Current operational Earthquake Early Warning Systems (EEWS) acquire data with networks of single seismic stations, and compute source parameters assuming earthquakes to be point sources. For large events, the point-source assumption leads to an underestimation of magnitude, and the use of single stations leads to large uncertainties in the locations of events outside the network. We propose the use of mini-arrays to improve EEWS. Mini-arrays have the potential to: (a) estimate reliable hypocentral locations by beam forming (FK-analysis) techniques; (b) characterize the rupture dimensions and account for finite-source effects, leading to more reliable estimates for large magnitudes. Previously, the high price of multiple seismometers has made creating arrays cost-prohibitive. However, we propose setting up mini-arrays of a new seismometer based on low-cost (<$150), high-performance MEMS accelerometer around conventional seismic stations. The expected benefits of such an approach include decreasing alert-times, improving real-time shaking predictions and mitigating false alarms. We use low-resolution 14-bit Quake Catcher Network (QCN) data collected during Rapid Aftershock Mobilization Program (RAMP) in Christchurch, NZ following the M7.1 Darfield earthquake in September 2010. As the QCN network was so dense, we were able to use small sub-array of up to ten sensors spread along a maximum area of 1.7x2.2 km2 to demonstrate our approach and to solve for the BAZ of two events (Mw4.7 and Mw5.1) with less than ±10° error. We will also present the new 24-bit device details, benchmarks, and real-time measurements.

  17. KINETICS STUDY ON KETOPROFEN RELEASE FROM MINI TABLETS AND MULTI-COMPARTMENT SYSTEMS.

    Science.gov (United States)

    Stawarski, Tomasz; Sieradzki, Edmund; Gałecka, Emilia; Binek, Karolina

    2016-01-01

    Thanks to multi-compartment systems it is possible to modify drug release. Two types of mini tablets containing 12.5 mg of ketoprofen were made: mini tablets of immediate (IR) and sustained (SR) release. Some of the tablets of immediate release were coated with an enteric coating, thereby obtaining a delayed release effect (IRc). For each tablet type, release profiles were tested in three media: 0.1 M HCl, phosphate buffer pH 4.5 and phosphate buffer pH 6.8. Based on the obtained results, three appropriate multi-compartment models have been constructed and tested. The factor limiting the amount of available ketoprofen at the absorption place is pH of the environment. It was observed that the increase in pH caused the increase of ketoprofen solubility. Constructed multi-compartment systems allowed to change the composition and the dose of medicinal substances easily. Thanks to this it is possible to adjust the release profile of the active substance to the individual patient, which meets the expectations of personalized medicine.

  18. Modified Titanium Implant as a Gateway to the Human Body: The Implant Mediated Drug Delivery System

    Directory of Open Access Journals (Sweden)

    Young-Seok Park

    2014-01-01

    Full Text Available The aim of this study was to investigate the efficacy of a proposed new implant mediated drug delivery system (IMDDS in rabbits. The drug delivery system is applied through a modified titanium implant that is configured to be implanted into bone. The implant is hollow and has multiple microholes that can continuously deliver therapeutic agents into the systematic body. To examine the efficacy and feasibility of the IMDDS, we investigated the pharmacokinetic behavior of dexamethasone in plasma after a single dose was delivered via the modified implant placed in the rabbit tibia. After measuring the plasma concentration, the areas under the curve showed that the IMDDS provided a sustained release for a relatively long period. The result suggests that the IMDDS can deliver a sustained release of certain drug components with a high bioavailability. Accordingly, the IMDDS may provide the basis for a novel approach to treating patients with chronic diseases.

  19. The first light of Mini-MegaTORTORA wide-field monitoring system

    CERN Document Server

    Biryukov, A; Karpov, S; Bondar, S; Ivanov, E; Katkova, E; Perkov, A; Sasyuk, V

    2014-01-01

    Here we describe the first light of the novel 9-channel wide-field optical monitoring system with sub-second temporal resolution, Mini-MegaTORTORA, which is being tested now at Special Astrophysical Observatory on Russian Caucasus. The system is able to observe the sky simultaneously in either wide (~900 square degrees) or narrow (~100 square degrees) fields of view, either in clear light or with any combination of color (Johnson B, V or R) polarimetric filters installed, with exposure times ranging from 100 ms to 100 s. The primary goal of the system is the detection of rapid -- with sub-second characteristic time-scales -- optical transients, but it may be also used for studying the variability of the sky objects on longer time scales.

  20. [Effects of irrigation fluid absorption on system during mini-percutaneous nephrolithotomy].

    Science.gov (United States)

    Li, Jiong-Ming; Liang, Ming; Wang, Guang; Liu, Jian-He; Chen, Jian; Jiang, Yong-Ming; Zhang, Jing-Song; Jia, Wan-Jian; Zhang, Hai-Yan

    2009-02-15

    To determine the effects of irrigation fluid absorption on system hemodynamics, fluid-electrolyte and hormone during mini-percutaneous nephrolithotomy. In this study 128 patients with renal calculus or calculus of superior ureter from January 2007 to February 2008 were collected. Hemoglobin (Hb), hematocrit (Hct), plasma osmotic pressure (POP), fluid-electrolyte, serum creatinine (Cre), renin, angiotensin II and aldosterone were determined before and after operation. Heart rate (HR), mean arterial blood pressure (MAP) and oxygen saturation (SPO(2)) were recorded dynamically every 30 min. The HR speeded up accompanied with the irrigation time. When compared with before operation, POP, Cl(-), renin and Cre were significantly increased after operation; Hb, Hct and K(+) were significantly decreased after operation; MAP, SPO(2), Na(+), aldosterone and angiotensin II did not change significantly after operation. No serious surgery-related complication occurred in all patients. Irrigation fluid is absorbed during mini-percutaneous nephrolithotomy. The absorption amount is positively correlated with irrigation time. Changes of hemodynamics, fluid-electrolyte balance and renin may be caused by the irrigation fluid absorption.

  1. Mini-med school for Aboriginal youth: experiential science outreach to tackle systemic barriers

    Directory of Open Access Journals (Sweden)

    Rita I. Henderson

    2015-12-01

    Full Text Available Introduction: Addressing systemic barriers experienced by low-income and minority students to accessing medical school, the University of Calgary's Cumming School of Medicine has spearheaded a year-round, mini-med school outreach initiative for Aboriginal students. Method: Junior and senior high school youth generally attend the half-day program in classes or camps of 15–25, breaking into small groups for multisession activities. Undergraduate medical education students mentor the youth in stations offering experiential lessons in physical examination, reading x-rays, and anatomy. All resources from the medical school are offered in-kind, including a pizza lunch at midday, whereas community partners organize transportation for the attendees. Results: Opening the medical school and its resources to the community offers great benefits to resource-constrained schools often limited in terms of science education resources. The model is also an effort to address challenges among the medical professions around attracting and retaining students from underserved populations. Conclusion: The prospect of increasing admission rates and successful completion of medical education among students from marginalized communities poses a real, though difficult-to-measure, possibility of increasing the workforce most likely to return to and work in such challenging contexts. A mini-medical school for Aboriginal youth highlights mutual, long-term benefit for diverse partners, encouraging medical educators and community-based science educators to explore the possibilities for deepening partnerships in their own regions.

  2. Micro- and nano-fabricated implantable drug-delivery systems

    OpenAIRE

    Meng, Ellis; Hoang, Tuan

    2012-01-01

    Implantable drug-delivery systems provide new means for achieving therapeutic drug concentrations over entire treatment durations in order to optimize drug action. This article focuses on new drug administration modalities achieved using implantable drug-delivery systems that are enabled by micro- and nano-fabrication technologies, and microfluidics. Recent advances in drug administration technologies are discussed and remaining challenges are highlighted.

  3. Exotic encounters with dental implants: managing complications with unidentified systems.

    Science.gov (United States)

    Mattheos, N; Janda, M Schittek

    2012-06-01

    As the application of dental implants increases worldwide, so is the number of technical and biological complications that general dental practitioners will be called to manage, while maintaining implant patients. In addition, the greater patient mobility encountered today combined with a growing trend of 'dental implant tourism' will very often result in situations where the dentist is requested to deal with complications in implants placed elsewhere and which sometimes might be of an 'exotic' system one cannot directly recognize. Such a situation can pose significant challenges to even experienced clinicians. The challenges are not only in the scientific field, but often include professional and ethical implications. This case report will discuss strategies for the management of implant complications in cases of unidentified implant systems. Critical factors in such situations would be the clinician's experience and special training, the correct radiographic technique, as well as access to the appropriate tools and devices.

  4. A Guidebook on Grid Interconnection and Islanded Operation of Mini-Grid Power Systems Up to 200 kW

    Energy Technology Data Exchange (ETDEWEB)

    Greacen, Chris [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Engel, Richard [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Quetchenbach, Thomas [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2013-04-01

    A Guidebook on Grid Interconnection and Islanded Operation of Mini-Grid Power Systems Up to 200 kW is intended to help meet the widespread need for guidance, standards, and procedures for interconnecting mini-grids with the central electric grid as rural electrification advances in developing countries, bringing these once separate power systems together. The guidebook aims to help owners and operators of renewable energy mini-grids understand the technical options available, safety and reliability issues, and engineering and administrative costs of different choices for grid interconnection. The guidebook is intentionally brief but includes a number of appendices that point the reader to additional resources for indepth information. Not included in the scope of the guidebook are policy concerns about “who pays for what,” how tariffs should be set, or other financial issues that are also paramount when “the little grid connects to the big grid.”

  5. Experimental investigation of commercial small diameter dental implants in porcine mandibular segments.

    Science.gov (United States)

    Hasan, Istabrak; Heinemann, Friedhelm; Schwegmann, Monika; Keilig, Ludger; Stark, Helmut; Bourauel, Christoph

    2017-02-01

    Small diameter (mini) dental implants have become more popular in recent years as alternatives to classical implant treatment in clinical cases with critical bony situations. However, an in-depth scientific analysis of the mechanical and biomechanical effects of small diameter implants has not yet been published. The aim of the present study was to investigate experimentally different commercial mini implants by measuring their displacements under immediate loading. Twelve commercially available mini implants were measured. Implants were inserted into porcine mandibular segments and loaded by means of a predefined displacement of 0.5 mm of the loading system. The implants were loaded at an angle of 30° to the implant long axis using the self-developed biomechanical hexapod measurement system. Implant displacements were registered. The experimental results were compared to the numerical ones from a previous study. Measured implant displacements were within the range of 39-194 μm. A large variation in the displacements was obtained among the different implant systems due to the different designs and thread profiles. Comparing experimental and numerical results, the displacements that were obtained numerically were within the range of 79-347 μm. The different commercial mini implants showed acceptable primary stability and could be loaded immediately after their insertion.

  6. Meteor observations with Mini-Mega-TORTORA wide-field monitoring system

    Science.gov (United States)

    Karpov, S.; Orekhova, N.; Beskin, G.; Biryukov, A.; Bondar, S.; Ivanov, E.; Katkova, E.; Perkov, A.; Sasyuk, V.

    2016-12-01

    Here we report on the results of meteor observations with 9-channel Mini-Mega-TORTORA (MMT-9) optical monitoring system with the wide field and high temporal resolution. During the first 1.5 years of operation more than 90 thousands of meteors have been detected, at a rate of 300-350 per night, with durations from 0.1 to 2.5 seconds and angular velocities up to 38 degrees per second. The faintest detected meteors have peak brightnesses about 10 mag, while the majority have them ranging from 4 to 8 mag. Some of the meteors have been observed in BVR filters simultaneously. Color variations along the trail for them have been determined. The parameters of the detected meteors have been published online. The database also includes data from 10 thousands of meteors detected by our previous FAVOR camera during 2006-2009.

  7. Avoider robot design to dim the fire with dt basic mini system

    CERN Document Server

    Prasetyo, Eri; Prabowo, Bumi Prabu

    2008-01-01

    Avoider robot is mean robot who is designed to avoid the block in around. Except that, this robot is also added by an addition application to dim the fire. This robot is made with ultrasonic sensor PING. This sensor is set on the front, right and left from robot. This sensor is used robot to look for the right street, so that robot can walk on. After the robot can look for the right street, next accomplished the robot is looking for the fire in around. And the next, dim the fire with fan. This robot is made with basic stamp 2 micro-controller. And that micro-controller can be found in dt-basic mini system module. This robot is made with servo motor on the right and left side, which is used to movement.

  8. Municipal Solid Waste Management using Geographical Information System aided methods: a mini review.

    Science.gov (United States)

    Khan, Debishree; Samadder, Sukha Ranjan

    2014-11-01

    Municipal Solid Waste Management (MSWM) is one of the major environmental challenges in developing countries. Many efforts to reduce and recover the wastes have been made, but still land disposal of solid wastes is the most popular one. Finding an environmentally sound landfill site is a challenging task. This paper addresses a mini review on various aspects of MSWM (suitable landfill site selection, route optimization and public acceptance) using the Geographical Information System (GIS) coupled with other tools. The salient features of each of the integrated tools with GIS are discussed in this paper. It is also addressed how GIS can help in optimizing routes for collection of solid wastes from transfer stations to disposal sites to reduce the overall cost of solid waste management. A detailed approach on performing a public acceptance study of a proposed landfill site is presented in this study. The study will help municipal authorities to identify the most effective method of MSWM.

  9. Mini tomato production in organic system under greenhouse with partial control of meteorological elements

    Directory of Open Access Journals (Sweden)

    Haroldo F. de Araujo

    Full Text Available ABSTRACT The objective of this research was to evaluate the meteorological elements of the environments and the production components of mini tomato crop in organic system in different forms of cultivation, biofertilizer doses and technological levels of protected environments. The research was conducted in completely randomized design in a 3 x 2 x 5 factorial scheme, corresponding to three greenhouses (A - climatized, B - mobile screen and C - fixed screen, two forms of cultivation (pots and beds and five doses of a commercial biofertilizer (0, 50, 100, 150 and 200% of dose indicated, with five replicates. The treatments affected the analyzed variables, except for biofertilizer doses and interaction of treatments. Air temperature was unchanged among the environments and the mean and minimum relative humidity were within the control range in the climatized greenhouse. The greenhouse with mobile screen showed the best production results for the cultivation in beds and the biofertilizer doses were indifferent for all treatments.

  10. Pulmonary vein isolation using the Rhythmia mapping system: Verification of intracardiac signals using the Orion mini-basket catheter.

    Science.gov (United States)

    Anter, Elad; Tschabrunn, Cory M; Contreras-Valdes, Fernando M; Li, Jianqing; Josephson, Mark E

    2015-09-01

    During pulmonary vein isolation (PVI), a circular lasso catheter is positioned at the junction between the left atrium (LA) and the pulmonary vein (PV) to confirm PVI. The Rhythmia mapping system uses the Orion mini-basket catheter with 64 electrodes instead of the lasso catheter. However, its feasibility to determine PVI has not been studied. The purpose of this study was to compare signals between the mini-basket and lasso catheters at the LA-PV junction. In 12 patients undergoing PVI using Rhythmia, the mini-basket and lasso catheters were placed simultaneously at the LA-PV junction for baseline and post-PVI signal assessment. Pacing from both catheters was performed to examine the presence of exit block. At baseline, recordings of LA and PV potentials were concordant in all PVs. However, after PVI, concordance between the catheters was only 68%. Discordance in all cases resulted from loss of PV potentials on the lasso catheter with persistence of PV potentials on the mini-basket catheter. In 9 of 13 PVs (69%), these potentials represented true PV potentials that were exclusively recorded with the smaller and closely spaced mini-basket electrodes. In the other 4 PVs (31%), these potentials originated from neighboring structures and resulted in underestimation of PVI. The use of the mini-basket catheter alone is sufficient to determine PVI. While it improves recording of PV potentials after incomplete ablation, it is also associated with frequent recording of "PV-like" potentials originating from neighboring structures. In these cases, pacing maneuvers are helpful to determine PVI and avoid excessive ablation. Copyright © 2015 Heart Rhythm Society. Published by Elsevier Inc. All rights reserved.

  11. Cranial implant design using augmented reality immersive system.

    Science.gov (United States)

    Ai, Zhuming; Evenhouse, Ray; Leigh, Jason; Charbel, Fady; Rasmussen, Mary

    2007-01-01

    Software tools that utilize haptics for sculpting precise fitting cranial implants are utilized in an augmented reality immersive system to create a virtual working environment for the modelers. The virtual environment is designed to mimic the traditional working environment as closely as possible, providing more functionality for the users. The implant design process uses patient CT data of a defective area. This volumetric data is displayed in an implant modeling tele-immersive augmented reality system where the modeler can build a patient specific implant that precisely fits the defect. To mimic the traditional sculpting workspace, the implant modeling augmented reality system includes stereo vision, viewer centered perspective, sense of touch, and collaboration. To achieve optimized performance, this system includes a dual-processor PC, fast volume rendering with three-dimensional texture mapping, the fast haptic rendering algorithm, and a multi-threading architecture. The system replaces the expensive and time consuming traditional sculpting steps such as physical sculpting, mold making, and defect stereolithography. This augmented reality system is part of a comprehensive tele-immersive system that includes a conference-room-sized system for tele-immersive small group consultation and an inexpensive, easily deployable networked desktop virtual reality system for surgical consultation, evaluation and collaboration. This system has been used to design patient-specific cranial implants with precise fit.

  12. Evolution of implantable and insertable drug delivery systems.

    Science.gov (United States)

    Kleiner, Lothar W; Wright, Jeremy C; Wang, Yunbing

    2014-05-10

    The paper describes the development of implantable and insertable drug delivery systems (IDDS) from their early stage in the 1960s until the current stage in the 2010s. It gives a detailed summary of non-degradable and biodegradable systems and their applications in different areas such as vascular disease treatment, birth control, cancer treatment, and eye disease treatment. It also describes the development of various implantable pump systems and some other atypical IDDS, the challenges and the future of IDDS.

  13. Mini-UAV based sensory system for measuring environmental variables in greenhouses.

    Science.gov (United States)

    Roldán, Juan Jesús; Joossen, Guillaume; Sanz, David; del Cerro, Jaime; Barrientos, Antonio

    2015-02-02

    This paper describes the design, construction and validation of a mobile sensory platform for greenhouse monitoring. The complete system consists of a sensory system on board a small quadrotor (i.e., a four rotor mini-UAV). The goals of this system include taking measures of temperature, humidity, luminosity and CO2 concentration and plotting maps of these variables. These features could potentially allow for climate control, crop monitoring or failure detection (e.g., a break in a plastic cover). The sensors have been selected by considering the climate and plant growth models and the requirements for their integration onboard the quadrotor. The sensors layout and placement have been determined through a study of quadrotor aerodynamics and the influence of the airflows from its rotors. All components of the system have been developed, integrated and tested through a set of field experiments in a real greenhouse. The primary contributions of this paper are the validation of the quadrotor as a platform for measuring environmental variables and the determination of the optimal location of sensors on a quadrotor.

  14. Mini-UAV Based Sensory System for Measuring Environmental Variables in Greenhouses

    Science.gov (United States)

    Roldán, Juan Jesús; Joossen, Guillaume; Sanz, David; del Cerro, Jaime; Barrientos, Antonio

    2015-01-01

    This paper describes the design, construction and validation of a mobile sensory platform for greenhouse monitoring. The complete system consists of a sensory system on board a small quadrotor (i.e., a four rotor mini-UAV). The goals of this system include taking measures of temperature, humidity, luminosity and CO2 concentration and plotting maps of these variables. These features could potentially allow for climate control, crop monitoring or failure detection (e.g., a break in a plastic cover). The sensors have been selected by considering the climate and plant growth models and the requirements for their integration onboard the quadrotor. The sensors layout and placement have been determined through a study of quadrotor aerodynamics and the influence of the airflows from its rotors. All components of the system have been developed, integrated and tested through a set of field experiments in a real greenhouse. The primary contributions of this paper are the validation of the quadrotor as a platform for measuring environmental variables and the determination of the optimal location of sensors on a quadrotor. PMID:25648713

  15. Mini-UAV Based Sensory System for Measuring Environmental Variables in Greenhouses

    Directory of Open Access Journals (Sweden)

    Juan Jesús Roldán

    2015-02-01

    Full Text Available This paper describes the design, construction and validation of a mobile sensory platform for greenhouse monitoring. The complete system consists of a sensory system on board a small quadrotor (i.e., a four rotor mini-UAV. The goals of this system include taking measures of temperature, humidity, luminosity and CO2 concentration and plotting maps of these variables. These features could potentially allow for climate control, crop monitoring or failure detection (e.g., a break in a plastic cover. The sensors have been selected by considering the climate and plant growth models and the requirements for their integration onboard the quadrotor. The sensors layout and placement have been determined through a study of quadrotor aerodynamics and the influence of the airflows from its rotors. All components of the system have been developed, integrated and tested through a set of field experiments in a real greenhouse. The primary contributions of this paper are the validation of the quadrotor as a platform for measuring environmental variables and the determination of the optimal location of sensors on a quadrotor.

  16. Prediction of druggable proteins using machine learning and systems biology: a mini-review

    Directory of Open Access Journals (Sweden)

    Gaurav eKandoi

    2015-12-01

    Full Text Available The emergence of -omics technologies has allowed the collection of vast amounts of data on biological systems. Although the pace of such collection has been exponential, the impact of these data remains small on many critical biomedical applications such as drug development. Limited resources, high costs and low hit-to-lead ratio have led researchers to search for more cost effective methodologies. A possible alternative is to incorporate computational methods of potential drug target prediction early during drug discovery workflow. Computational methods based on systems approaches have the advantage of taking into account the global properties of a molecule not limited to its sequence, structure or function. Machine learning techniques are powerful tools that can extract relevant information from massive and noisy data sets. In recent years the scientific community has explored the combined power of these fields to propose increasingly accurate and low cost methods to propose interesting drug targets. In this mini-review, we describe promising approaches based on the simultaneous use of systems biology and machine learning to access gene and protein druggability. Moreover, we discuss the state-of-the-art of this emerging and interdisciplinary field, discussing data sources, algorithms and the performance of the different methodologies. Finally, we indicate interesting avenues of research and some remaining open challenges.

  17. Study on Mini Re-Entry System Using Deployable Membrane Aeroshell

    Science.gov (United States)

    Koyama, Masashi; Suzuki, Kojiro; Imamura, Osamu; Yamada, Kazuhiko

    An aeroshell made from membrane material have an advantage of reduction in the aerodynamic heating, because its small mass and large area enable us to make the low-ballistic-coefficient flight, in which the vehicle decelerates at very high altitude with low atmospheric density. In this paper, we propose a new concept of mini re-entry system for small satellites. This vehicle is called "FEATHER" (Flexible Expanded Aeroshell with Tiny payload Harness for Entry and Recovery). "FEATHER" is a novel re-entry and recovery system, featuring the autonomous aeroshell deployment, the low-ballistic-coefficient re-entry with less severe aerodynamicc heating and so on. FEATHER is composed of the membrane aeroshell made from the high-temperature cloth called ZYLON®, an outer frame made of Shape Memory Alloy (SMA) and a payload. When the aeroshell receives the aerodynamic heating, the temperature of SMA frame rises and restores the circular shape as memorized beforehand. Then the membrane aeroshell is automatically deployed. Therefore the vehicle can achieve the low-ballistic-coefficient flight with a drastic reduction in the aerodynamic heating without any additional sensors, controllers and actuators. The preliminary studies made on FEATHER system so far including the hypersonic wind tunnel experiments are presented in this paper.

  18. Remote powering and data communication for implanted biomedical systems

    CERN Document Server

    Kilinc, Enver Gurhan; Maloberti, Franco

    2016-01-01

    This book describes new circuits and systems for implantable biomedical applications and explains the design of a batteryless, remotely-powered implantable micro-system, designed for long-term patient monitoring.  Following new trends in implantable biomedical applications, the authors demonstrate a system which is capable of efficient, remote powering and reliable data communication.  Novel architecture and design methodologies are used to transfer power with a low-power, optimized inductive link and data is transmitted by a reliable communication link.  Additionally, an electro-mechanical solution is presented for tracking and monitoring the implantable system, while the patient is mobile.  ·         Describes practical example of an implantable batteryless biomedical system; ·         Analyzes and compares various energy harvesting and power transfer methods; ·         Describes design of remote powering link and data communication of the implantable system, comparing differe...

  19. Benchmarking Further Single Board Computers for Building a Mini Supercomputer for Simulation of Telecommunication Systems

    Directory of Open Access Journals (Sweden)

    Gábor Lencse

    2016-01-01

    Full Text Available Parallel Discrete Event Simulation (PDES with the conservative synchronization method can be efficiently used for the performance analysis of telecommunication systems because of their good lookahead properties. For PDES, a cost effective execution platform may be built by using single board computers (SBCs, which offer relatively high computation capacity compared to their price or power consumption and especially to the space they take up. A benchmarking method is proposed and its operation is demonstrated by benchmarking ten different SBCs, namely Banana Pi, Beaglebone Black, Cubieboard2, Odroid-C1+, Odroid-U3+, Odroid-XU3 Lite, Orange Pi Plus, Radxa Rock Lite, Raspberry Pi Model B+, and Raspberry Pi 2 Model B+. Their benchmarking results are compared to find out which one should be used for building a mini supercomputer for parallel discrete-event simulation of telecommunication systems. The SBCs are also used to build a heterogeneous cluster and the performance of the cluster is tested, too.

  20. Systemic Assessment of Patients Undergoing Dental Implant ...

    African Journals Online (AJOL)

    Background: Procedure‑related and patient‑related factors influence the prognosis of dental implants ... Results: Out of 51, 29 patients were males while 22 were females, with ratio of 1.32:1. ... difference of average STAI‑State subscore before and after the surgery was ... bleeding, swelling, bruising, pain, and tenderness to.

  1. Design, Development and Testing of the Miniature Autonomous Extravehicular Robotic Camera (Mini AERCam) Guidance, Navigation and Control System

    Science.gov (United States)

    Wagenknecht, J.; Fredrickson, S.; Manning, T.; Jones, B.

    2003-01-01

    Engineers at NASA Johnson Space Center have designed, developed, and tested a nanosatellite-class free-flyer intended for future external inspection and remote viewing of human spaceflight activities. The technology demonstration system, known as the Miniature Autonomous Extravehicular Robotic Camera (Mini AERCam), has been integrated into the approximate form and function of a flight system. The primary focus has been to develop a system capable of providing external views of the International Space Station. The Mini AERCam system is spherical-shaped and less than eight inches in diameter. It has a full suite of guidance, navigation, and control hardware and software, and is equipped with two digital video cameras and a high resolution still image camera. The vehicle is designed for either remotely piloted operations or supervised autonomous operations. Tests have been performed in both a six degree-of-freedom closed-loop orbital simulation and on an air-bearing table. The Mini AERCam system can also be used as a test platform for evaluating algorithms and relative navigation for autonomous proximity operations and docking around the Space Shuttle Orbiter or the ISS.

  2. Report on a 2009 mini-demonstration of the ARG-US Radio Frequency Identification (RFID) system in transportation.

    Energy Technology Data Exchange (ETDEWEB)

    Tsai, H.; Chen, K.; Jusko, M.; Craig, B.; Liu, Y.; Decision and Information Sciences

    2009-11-23

    The Packaging Certification Program (PCP) of the U.S. Department of Energy (DOE) Environmental Management (EM), Office of Packaging and Transportation (EM-14), has developed a radio frequency identification (RFID) tracking and monitoring system for the management of nuclear materials during storage and transportation. The system, developed by the PCP team at Argonne National Laboratory, consists of hardware (Mk-series sensor tags, fixed and handheld readers, form factor for multiple drum types, seal integrity sensors, and enhanced battery management), software (application programming interface, ARG-US software for local and remote/web applications, secure server and database management), and cellular/satellite communication interfaces for vehicle tracking and item monitoring during transport. The ability of the above system to provide accurate, real-time tracking and monitoring of the status of multiple, certified containers of nuclear materials has been successfully demonstrated in a week-long, 1,700-mile DEMO performed in April 2008. While the feedback from the approximately fifty (50) stakeholders who participated in and/or observed the DEMO progression were very positive and encouraging, two major areas of further improvements - system integration and web application enhancement - were identified in the post-DEMO evaluation. The principal purpose of the MiniDemo described in this report was to verify these two specific improvements. The MiniDemo was conducted on August 28, 2009. In terms of system integration, a hybrid communication interface - combining the RFID item-monitoring features and a commercial vehicle tracking system by Qualcomm - was developed and implemented. In the MiniDemo, the new integrated system worked well in reporting tag status and vehicle location accurately and promptly. There was no incompatibility of components. The robust commercial communication gear, as expected, helped improve system reliability. The MiniDemo confirmed that system

  3. Report on a 2009 mini-demonstration of the ARG-US Radio Frequency Identification (RFID) system in transportation.

    Energy Technology Data Exchange (ETDEWEB)

    Tsai, H.; Chen, K.; Jusko, M.; Craig, B.; Liu, Y.; Decision and Information Sciences

    2009-11-23

    The Packaging Certification Program (PCP) of the U.S. Department of Energy (DOE) Environmental Management (EM), Office of Packaging and Transportation (EM-14), has developed a radio frequency identification (RFID) tracking and monitoring system for the management of nuclear materials during storage and transportation. The system, developed by the PCP team at Argonne National Laboratory, consists of hardware (Mk-series sensor tags, fixed and handheld readers, form factor for multiple drum types, seal integrity sensors, and enhanced battery management), software (application programming interface, ARG-US software for local and remote/web applications, secure server and database management), and cellular/satellite communication interfaces for vehicle tracking and item monitoring during transport. The ability of the above system to provide accurate, real-time tracking and monitoring of the status of multiple, certified containers of nuclear materials has been successfully demonstrated in a week-long, 1,700-mile DEMO performed in April 2008. While the feedback from the approximately fifty (50) stakeholders who participated in and/or observed the DEMO progression were very positive and encouraging, two major areas of further improvements - system integration and web application enhancement - were identified in the post-DEMO evaluation. The principal purpose of the MiniDemo described in this report was to verify these two specific improvements. The MiniDemo was conducted on August 28, 2009. In terms of system integration, a hybrid communication interface - combining the RFID item-monitoring features and a commercial vehicle tracking system by Qualcomm - was developed and implemented. In the MiniDemo, the new integrated system worked well in reporting tag status and vehicle location accurately and promptly. There was no incompatibility of components. The robust commercial communication gear, as expected, helped improve system reliability. The MiniDemo confirmed that system

  4. Generating thermal energy and electric power by yourself. Heating system modernization with a mini dual-purpose power plant; Waerme und Strom selbst erzeugen. Heizungsmodernisierung mit Mini-BHKW

    Energy Technology Data Exchange (ETDEWEB)

    Meissner, H. [Powerplus Technologies GmbH, Gera (Germany)

    2008-03-15

    Mini dual-purpose power plants offer many advantages to the customer by means of reduced primary energy consumoption, reduced CO{sub 2} emission and considerable savings of energy costs. The following contribution describes the balance in the one-family house of the Gross family and what heating systems master craftsman Keijo Sprogoetook into consideration when he executed this modernization task. (orig.)

  5. Mini-Raft Backpack Development.

    Science.gov (United States)

    1983-01-01

    AD-R14i 301 MINI-RAFT BACKPACK DEVELOPMENT(U) NAVAL AIRil IIIDEVELOPMENT CENTER WARMINSTER PA AIRCRAFT AND CREW SYSTEMS TECHNOLOGY DIRECTORATE G P...GOVT ACCESSION NO. 3. RECIPIENT’S CATALOG NUMBER NADC-83097-60 4. TITLE (and Sublitle) S. TYPE OF REPORT & PERIOD COVERED MINI-RAFT BACKPACK ...number) Mini-Raft, Backpack , Mini-Boat, Life Raft, One !-an, Vee Bottom RW" 24. ABSTRACT (Contnue on revere eld* i necessary and Identify by block number

  6. Alstom launches new mini hydro range

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    LSTOM POWER HYDRO has announced the launch of a complete mini hydro solution. Named Mini-Aqua, the product has been developed to integrate the hydro turbine, generator and control system in a single and optimised product.

  7. miniPixD: a compact sample analysis system which combines X-ray imaging and diffraction

    Science.gov (United States)

    Moss, Robert; Crews, Chiaki; Wilson, Matthew; Speller, Robert

    2017-02-01

    This paper introduces miniPixD: a new, compact system that utilises transmission X-ray imaging and X-ray diffraction (XRD) to locate and identify materials of interest within an otherwise opaque volume. The system and the embodied techniques have utility in security screening, medical diagnostics, non-destructive testing (NDT) and quality assurance (QA). This paper outlines the design of the system including discussion on the choice of components and presents some data from relevant samples which are compared to other energy dispersive and angular dispersive XRD techniques.

  8. A mini-electrochemical system integrated micropipet tip and pencil graphite electrode for detection of anticancer drug sensitivity in vitro.

    Science.gov (United States)

    Guo, Xiaoling; Wang, Qian; Li, Jinlian; Cui, Jiwen; Zhou, Shi; Hao, Sue; Wu, Dongmei

    2015-02-15

    Developing a reliable and cost-effective miniaturized electroanalysis tool is of vital importance for cell electrochemical analysis. In this work, a novel mini-electrochemical system has been constructed for trace detection of cell samples. The mini-electrochemical system was constructed by integrating a pencil graphite modified by threonine (PT/PGE) as working electrode, an Ag/AgCl (Sat'd) as reference electrode, platinum wire as counter electrode and a micropipet tip as electrochemical cell. The mini-electrochemical system not only saved dramatically usage of samples from 500 μL in traditional electrochemical system to 10 μL, but also possessed an adjustable active surface area by changing the length of PT/PGE immersed into the cell suspension from 3mm to 15 mm, and the linear equation was ipa = 2.25 l-2.64 (R(2) = 0.990). The system was successfully used in detection of MCF-7 cells, and a nonlinear exponent relationship between peak current and the cell number range from 3.0 × l0(3) to 7.0 × l0(6) cells mL(-1) was established firstly with the index equation ipa = 59.557 e (-C/1.709)-71.486 (R(2) = 0.954). Finally, the system was used for evaluating the sensitivity of cyclophosphamide on MCF-7 cell, and the result was corresponded well with that of MTT assay. The proposed system is sufficiently simple, cheap and easy operated, and could be applied in electrochemical detection of other biological samples.

  9. 微种植体支抗治疗开唇露齿的相关牙根吸收的研究%Root resorption of patients used mini-implant anchorage to treat poor lip seal

    Institute of Scientific and Technical Information of China (English)

    陈馨; 王林; 沈小波; 冯兴梅

    2013-01-01

    Objective:To evaluate the outcome and factors of root resorption in patients who used mini-implant to treat poor lip seal. Methods: Eighteen subjects(age 12-23 years) with poor lip seal were allocated in the study. The patients all had maxillary dentoalveolar protrusion and extrated two first premolars. They were divided into two groups:A group (mini-implant anchorage) 9 patients and B group (regular anchorage) 9 patients. A group used 3 implants and B group used Nance plate for the treatment. The length of incisors was measured in record model , panoramic and cephalometric radiograph. Results: Root resorption was found in both group. The degree of the root resorption in mini-implant anchorage group was higher than that in reg-ular anchorage (P<0.05). Conclusions:Root resorption was found in all of the patients with poor lip seal. The use of mini-implant anchorage will lead more root resorption. The force chose and early imaging examination should be noticed during the treatment.%目的:探讨使用微种植体支抗辅助治疗开唇露齿后牙根吸收的状况及相关因素。方法:选取18例开唇露齿采取正畸治疗的患者,年龄12~23岁,上颌或双颌前突,前牙唇倾,上颌均拔除第一前磨牙。分为实验组(种植支抗)9例和对照组(传统支抗)9例,实验组使用前后牙区共3枚种植钉支抗系统,对照组使用Nance托。正畸前后制取模型及拍摄全景片,头颅定位侧位片,测量相关指标并进行分析。结果:两组患者的上中切牙牙根均明显吸收,微种植支抗组大于传统支抗组(P<0.01)。结论:治疗开唇露齿的患者,前牙内收压低后均有不同程度的牙根吸收,使用微种植体支抗会更明显,治疗期间需注意力量控制及影像监测。

  10. Macrokinetic calculation of the ignition of a solid-fuel charge of glycidyl azide polymer in the mini-engine of a microelectromechanical system

    Science.gov (United States)

    Fut'ko, S. I.; Ermolaeva, E. M.; Dobrego, K. V.; Bondarenko, V. P.; Dolgii, L. N.

    2011-11-01

    The process of ignition of the solid fuel from glycidyl azide polymer in the mini-engine of a microelectromechanical system has been considered. Macrokinetic calculations of the self-ignition temperature of the fuel and the induction period for different heat transfer conditions have been made. On the basis of the critical thermal flux determination, recommendations on the choice of the minimum power and size of the thermistor in the igniter of the solid-fuel mini-engine have been formulated.

  11. Construction of two fluorescence-labeled non-combined DNA index system miniSTR multiplex systems to analyze degraded DNA samples in the Chinese Han Population.

    Science.gov (United States)

    Bai, Xue; Li, Shujin; Cong, Bin; Li, Xia; Guo, Xia; He, Lujun; Ye, Jian; Pei, Li

    2010-09-01

    MiniSTR loci have been demonstrated to be an effective approach in recovering genetic information from degraded specimens, because of the reduced PCR amplicon sizes which improved the PCR efficiency. Eight non-combined DNA index system miniSTR loci suitable for the Chinese Han Population were analyzed in 300 unrelated Chinese Han individuals using two novel five fluorescence-labeled miniSTR multiplex systems(multiplex I: D10S1248, D2S441, D1S1677 and D9S2157; multiplex II: D9S1122, D10S1435, D12ATA63, D2S1776 and Amelogenin). The allele frequency distribution and forensic parameters in the Chinese Han Population were reported in this article. The Exact Test demonstrated that all loci surveyed here were found to be no deviation from Hardy-Weinberg equilibrium. The accumulated power of discrimination and power of exclusion for the eight loci were 0.999999992 and 0.98, respectively. The highly degraded DNA from artificially degraded samples and the degraded forensic case work samples was assessed with the two miniSTR multiplex systems, and the results showed that the systems were quite effective.

  12. Wireless energizing system for an automated implantable sensor

    Energy Technology Data Exchange (ETDEWEB)

    Swain, Biswaranjan; Nayak, Praveen P.; Kar, Durga P.; Bhuyan, Satyanarayan; Mishra, Laxmi P. [Department of Electronics and Instrumentation Engineering, Siksha ‘O’ Anusandhan University, Bhubaneswar 751030 (India)

    2016-07-15

    The wireless drive of an automated implantable electronic sensor has been explored for health monitoring applications. The proposed system comprises of an automated biomedical sensing system which is energized through resonant inductive coupling. The implantable sensor unit is able to monitor the body temperature parameter and sends back the corresponding telemetry data wirelessly to the data recoding unit. It has been observed that the wireless power delivery system is capable of energizing the automated biomedical implantable electronic sensor placed over a distance of 3 cm from the power transmitter with an energy transfer efficiency of 26% at the operating resonant frequency of 562 kHz. This proposed method ensures real-time monitoring of different human body temperatures around the clock. The monitored temperature data have been compared with a calibrated temperature measurement system to ascertain the accuracy of the proposed system. The investigated technique can also be useful for monitoring other body parameters such as blood pressure, bladder pressure, and physiological signals of the patient in vivo using various implantable sensors.

  13. Wireless energizing system for an automated implantable sensor

    Science.gov (United States)

    Swain, Biswaranjan; Nayak, Praveen P.; Kar, Durga P.; Bhuyan, Satyanarayan; Mishra, Laxmi P.

    2016-07-01

    The wireless drive of an automated implantable electronic sensor has been explored for health monitoring applications. The proposed system comprises of an automated biomedical sensing system which is energized through resonant inductive coupling. The implantable sensor unit is able to monitor the body temperature parameter and sends back the corresponding telemetry data wirelessly to the data recoding unit. It has been observed that the wireless power delivery system is capable of energizing the automated biomedical implantable electronic sensor placed over a distance of 3 cm from the power transmitter with an energy transfer efficiency of 26% at the operating resonant frequency of 562 kHz. This proposed method ensures real-time monitoring of different human body temperatures around the clock. The monitored temperature data have been compared with a calibrated temperature measurement system to ascertain the accuracy of the proposed system. The investigated technique can also be useful for monitoring other body parameters such as blood pressure, bladder pressure, and physiological signals of the patient in vivo using various implantable sensors.

  14. SpaceCube Mini

    Science.gov (United States)

    Lin, Michael; Petrick, David; Geist, Alessandro; Flatley, Thomas

    2012-01-01

    This version of the SpaceCube will be a full-fledged, onboard space processing system capable of 2500+ MIPS, and featuring a number of plug-andplay gigabit and standard interfaces, all in a condensed 3x3x3 form factor [less than 10 watts and less than 3 lb (approximately equal to 1.4 kg)]. The main processing engine is the Xilinx SIRF radiation- hardened-by-design Virtex-5 FX-130T field-programmable gate array (FPGA). Even as the SpaceCube 2.0 version (currently under test) is being targeted as the platform of choice for a number of the upcoming Earth Science Decadal Survey missions, GSFC has been contacted by customers who wish to see a system that incorporates key features of the version 2.0 architecture in an even smaller form factor. In order to fulfill that need, the SpaceCube Mini is being designed, and will be a very compact and low-power system. A similar flight system with this combination of small size, low power, low cost, adaptability, and extremely high processing power does not otherwise exist, and the SpaceCube Mini will be of tremendous benefit to GSFC and its partners. The SpaceCube Mini will utilize space-grade components. The primary processing engine of the Mini is the Xilinx Virtex-5 SIRF FX-130T radiation-hardened-by-design FPGA for critical flight applications in high-radiation environments. The Mini can also be equipped with a commercial Xilinx Virtex-5 FPGA with integrated PowerPCs for a low-cost, high-power computing platform for use in the relatively radiation- benign LEOs (low-Earth orbits). In either case, this version of the Space-Cube will weigh less than 3 pounds (.1.4 kg), conform to the CubeSat form-factor (10x10x10 cm), and will be low power (less than 10 watts for typical applications). The SpaceCube Mini will have a radiation-hardened Aeroflex FPGA for configuring and scrubbing the Xilinx FPGA by utilizing the onboard FLASH memory to store the configuration files. The FLASH memory will also be used for storing algorithm and

  15. In vivo determination of aluminum, cobalt, chromium, copper, nickel, titanium and vanadium in oral mucosa cells from orthodontic patients with mini-implants by Inductively coupled plasma-mass spectrometry (ICP-MS).

    Science.gov (United States)

    Martín-Cameán, Ana; Jos, Angeles; Puerto, Maria; Calleja, Ana; Iglesias-Linares, Alejandro; Solano, Enrique; Cameán, Ana M

    2015-10-01

    Miniscrews are used as orthodontic anchorage devices in the dentistry clinical practice but the in vivo metallic release from these structures has been not previously investigated. The aim of this study was to determine the content of Al, Co, Cr, Cu, Ni, Ti and V in oral mucosa cells of control subjects, patients under orthodontic treatment and with both, orthodontic treatment and miniscrew, in order to know the contribution of these mini-implants to the total metallic content. ICP-MS measurements revealed the following ascending order: Cr

  16. Comparative Experimental Analysis of the Thermal Performance of Evacuated Tube Solar Water Heater Systems With and Without a Mini-Compound Parabolic Concentrating (CPC Reflector(C < 1

    Directory of Open Access Journals (Sweden)

    Yuehong Su

    2012-04-01

    Full Text Available Evacuated tube solar water heater systems are widely used in China due to their high thermal efficiency, simple construction requirements, and low manufacturing costs. CPC evacuated tube solar water heaters with a geometrical concentration ratio C of less than one are rare. A comparison of the experimental rig of evacuated tube solar water heater systems with and without a mini-CPC reflector was set up, with a series of experiments done in Hefei (31°53'N, 117°15'E, China. The first and second laws of thermodynamics were used to analyze and contrast their thermal performance. The water in the tank was heated from 26.9 to 55, 65, 75, 85, and 95 °C. Two types of solar water heater systems were used, and the data gathered for two days were compared. The results show that when attaining low temperature water, the evacuated tube solar water heater system without a mini-CPC reflector has higher thermal and exergy efficiencies than the system with a mini-CPC reflector, including the average and immediate values. On the other hand, when attaining high temperature water, the system with a mini-CPC reflector has higher thermal and exergy efficiencies than the other one. The comparison presents the advantages of evacuated tube solar water heater systems with and without a mini-CPC reflector, which can be offered as a reference when choosing which solar water system to use for actual applications.

  17. MiniSTR multiplex systems based on non-CODIS loci for analysis of degraded DNA samples.

    Science.gov (United States)

    Asamura, H; Fujimori, S; Ota, M; Fukushima, H

    2007-11-15

    We describe two short amplicon autosomal short tandem repeat (miniSTR) quadruplex systems for eight loci D1S1171, D2S1242, D3S1545, D4S2366, D12S391, D16S3253, D20S161, and D21S1437, unlinked from the combined DNA index system (non-CODIS) loci, using newly designed primer sets. The results of an assay of 411 Japanese individuals showed that polymerase chain reaction (PCR) products within the eight loci were less than 150bp in size, without the seven additional bases for adenylation. The frequency distributions in the loci showed no deviations from Hardy-Weinberg equilibrium expectations. The accumulated power of discrimination and power of exclusion for the eight loci were 0.9999999991 and 0.998, respectively. For assay of highly degraded DNA, including artificially degraded samples and the degraded forensic casework samples assessed with the present miniSTR quadruplex systems, the systems proved quite effective in analyzing degraded DNA.

  18. Implantação de um mini-pacs (sistema de arquivamento e distribuição de imagens em hospital universitário Mini-PACS (picture archiving and communication system implementation at a university hospital

    Directory of Open Access Journals (Sweden)

    Paulo Mazzoncini de Azevedo-Marques

    2001-08-01

    Full Text Available Este trabalho apresenta a implementação de um mini-PACS (sistema de arquivamento e comunicação de imagens que está sendo estruturado junto ao Serviço de Radiodiagnóstico do Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo, como parte do projeto de um serviço de radiologia digital ("filmless".This paper describes the implementation of a mini-PACS (picture archiving and communication system at a university hospital ("Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo", as a component of a project for a filmless radiology facility.

  19. Unpack, plug in, ready? A mini solar system can be connected to any outlet - but this alone is not sufficient; Auspacken, einstecken, fertig? Eine Mini-Solaranlage kann an jede Steckdose angeschlossen werden - doch das allein reicht nicht

    Energy Technology Data Exchange (ETDEWEB)

    Siemer, Jochen

    2013-05-15

    ''Guerrilla Solar'' is the keyword: mini photovoltaic systems of one or two modules and a micro-inverter one can stand on the balcony or wherever there's room and simply connects to the power outlet. The idea is not new, but an acceptable technical solution with the current standards in Germany is difficult. Both - technology and standards - need to be improved. [German] ''Guerilla Solar'' heisst das Schlagwort: Mini-Photovoltaikanlagen aus einem oder zwei Modulen und einem Kleinst-Wechselrichter, die man sich auf den Balkon stellt oder wo sonst gerade Platz ist und einfach an die Steckdose anschliesst. Die Idee ist nicht neu, doch eine mit den in Deutschland geltenden Normen vertraegliche technische Loesung gestaltet sich schwierig. Beides - Technik und Normen - ist verbesserungswuerdig.

  20. Systemic drug delivery systems for bone tissue regeneration- a mini review.

    Science.gov (United States)

    Xinluan, Wang; Yuxiao, Lai; Helena, Ng HueiLeng; Zhijun, Yang; Ling, Qin

    2015-01-01

    Musculoskeletal metabolic diseases such as osteoporosis have become the major public health problems worldwide in our aging society. Pharmaceutical therapy is one of the approaches to prevent and treat related medical conditions. Most of the clinically used anti-osteoporotic drugs are administered systemically and have demonstrated some side effects in non-skeletal tissues. One of the innovative approaches to prevent potential adverse effects is the development of bone-targeting drug delivery technologies that not only minimizes the systemic toxicity but also improves the pharmacokinetic profile and therapeutic efficacy of chemical drugs. This paper reviews the currently available bone targeting drug delivery systems with emphasis as bone-targeting moieties, including the bonesurface- site-specific (bone formation dominant or bone resorption dominant) and cell-specific moieties. In addition, the connections of drug-bone-targeting moieties-carrier are also summarized, and the newly developed liposomes and nanoparticles are discussed for their potential use and main challenges in delivering therapeutic agents to bone tissue. As a rapid-developing biotechnology, systemic bonetargeting delivery system is promising but still in its infancy where challenges are ahead of us, including the stability and the toxicity issues, especially to fulfill the regulatory requirement to realize bench-to-bedside translation. Newly developed biomaterials and technologies with potential for safer and more effective drug delivery require multidisciplinary collaborations with preclinical and clinical scientists that are essential to facilitate their clinical applications.

  1. Experimental Study of Single Phase Flow in a Closed-Loop Cooling System with Integrated Mini-Channel Heat Sink

    Directory of Open Access Journals (Sweden)

    Lei Ma

    2016-06-01

    Full Text Available The flow and heat transfer characteristics of a closed-loop cooling system with a mini-channel heat sink for thermal management of electronics is studied experimentally. The heat sink is designed with corrugated fins to improve its heat dissipation capability. The experiments are performed using variable coolant volumetric flow rates and input heating powers. The experimental results show a high and reliable thermal performance using the heat sink with corrugated fins. The heat transfer capability is improved up to 30 W/cm2 when the base temperature is kept at a stable and acceptable level. Besides the heat transfer capability enhancement, the capability of the system to transfer heat for a long distance is also studied and a fast thermal response time to reach steady state is observed once the input heating power or the volume flow rate are varied. Under different input heat source powers and volumetric flow rates, our results suggest potential applications of the designed mini-channel heat sink in cooling microelectronics.

  2. Implant survivorship analysis after minimally invasive sacroiliac joint fusion using the iFuse Implant System®

    Directory of Open Access Journals (Sweden)

    Cher DJ

    2015-11-01

    Full Text Available Daniel J Cher,1 W Carlton Reckling,2 Robyn A Capobianco1 1Department of Clinical Affairs, SI-BONE, Inc., 2Department of Medical Affairs, SI-BONE, Inc., San Jose, CA, USA Introduction: Surgical revision rate is a key outcome with all permanent implants. The iFuse Implant System® is a permanent implant used to perform minimally invasive sacroiliac joint fusion. The purpose of this study is to determine the surgical revision rate after sacroiliac joint fusion surgery with this system. Methods: Using two internal sources of information, revision surgeries were identified and linked to index surgeries. The likelihood of revision surgery was calculated using the Kaplan–Meier life table approach. Predictors of revision were explored. Results: Four-year survivorship free from implant revision was 96.46%. Revision rate did not differ by sex and was lower for age >65. In all, 24% of revisions occurred within the first 30 days after surgery; 63.5% occurred within year 1. Implant survivorship has improved annually since the device was introduced in 2009. Conclusion: The survivorship rate with this implant is high and improving; the rate is somewhat higher than total hip replacement but lower than that of lumbar spine procedures. Keywords: safety, sacroiliac joint fusion, iFuse Implant System, revision

  3. Three Filtered Vacuum Arc Plasma Sources Deposition & Implantation System

    Institute of Scientific and Technical Information of China (English)

    WU Xian-ying; ZHANG Hui-xing; LI Qiang

    2004-01-01

    A deposition & implantation system, which includes three filtered vacuum arc plasma sources, has been built. Vacuum arc discharge is used to produce high-density metal plasma; Curved magnetic filtering technique is used to transfer the plasma into out-of-sight vacuum chamber and reduce macro-particles from the vacuum arc plasma in order to drastically reduce the macro-particles contamination of the films. The up to 30 kV negative bias applied to the target can be used for ion implantation in order to improve the film adhesion; or for ion sputtering to clear the substrate surface. The 0 to 300 V negative bias can be used to adjust the ion energy which forming films. The system is designed for various thin films synthesizing, such as single-layer, compound layer, multi-layer films. It's principle, components and applications are described in the literature.

  4. Mini-MegaTORTORA wide-field monitoring system with sub-second temporal resolution: observation of transient events

    Science.gov (United States)

    Karpov, S.; Beskin, G.; Biryukov, A.; Bondar, S.; Ivanov, E.; Katkova, E.; Perkov, A.; Sasyuk, V.

    2016-06-01

    Here we present a summary of first years of operation and first results of a novel 9-channel wide-field optical monitoring system with sub-second temporal resolution, Mini-MegaTORTORA (MMT-9), which is in operation now at Special Astrophysical Observatory on Russian Caucasus. The system is able to observe the sky simultaneously in either wide (~900 square degrees) or narrow (~100 square degrees) fields of view, either in clear light or with any combination of color (Johnson-Cousins B, V or R) and polarimetric filters installed, with exposure times ranging from 0.1 s to hundreds of seconds. The real-time system data analysis pipeline performs automatic detection of rapid transient events, both near-Earth and extragalactic. The objects routinely detected by MMT include faint meteors and artificial satellites. The pipeline for a longer time scales variability analysis is still in development.

  5. Mini-Mega-TORTORA wide-field monitoring system with sub-second temporal resolution: first year of operation

    Science.gov (United States)

    Karpov, S.; Beskin, G.; Biryukov, A.; Bondar, S.; Ivanov, E.; Katkova, E.; Perkov, A.; Sasyuk, V.

    2016-12-01

    Here we present the summary of first years of operation and the first results of a novel 9-channel wide-field optical monitoring system with sub-second temporal resolution, Mini-Mega-TORTORA (MMT-9), which is in operation now at Special Astrophysical Observatory on Russian Caucasus. The system is able to observe the sky simultaneously in either wide (˜900 square degrees) or narrow (˜100 square degrees) fields of view, either in clear light or with any combination of color (Johnson-Cousins B, V or R) and polarimetric filters installed, with exposure times ranging from 0.1 s to hundreds of seconds. The real-time system data analysis pipeline performs automatic detection of rapid transient events, both near-Earth and extragalactic. The objects routinely detected by MMT include faint meteors and artificial satellites. The pipeline for a longer time scales variability analysis is still in development.

  6. Observations of transient events with Mini-MegaTORTORA wide-field monitoring system with sub-second temporal resolution

    Science.gov (United States)

    Karpov, S.; Beskin, G.; Biryukov, A.; Bondar, S.; Ivanov, E.; Katkova, E.; Orekhova, N.; Perkov, A.; Sasyuk, V.

    2017-07-01

    Here we present the summary of first years of operation and the first results of a novel 9-channel wide-field optical monitoring system with sub-second temporal resolution, Mini-MegaTORTORA (MMT-9), which is in operation now at Special Astrophysical Observatory on Russian Caucasus. The system is able to observe the sky simultaneously in either wide (900 square degrees) or narrow (100 square degrees) fields of view, either in clear light or with any combination of color (Johnson-Cousins B, V or R) and polarimetric filters installed, with exposure times ranging from 0.1 s to hundreds of seconds.The real-time system data analysis pipeline performs automatic detection of rapid transient events, both near-Earth and extragalactic. The objects routinely detected by MMT also include faint meteors and artificial satellites.

  7. Mini-MegaTORTORA Wide-Field Monitoring System with Subsecond Temporal Resolution: Observation of Transient Events

    Science.gov (United States)

    Karpov, S.; Beskin, G.; Biryukov, A.; Bondar, S.; Ivanov, E.; Katkova, E.; Orekhova, N.; Perkov, A.; Sasyuk, V.

    2017-06-01

    Here we present the summary of first years of operation and the first results of a novel 9-channel wide-field optical monitoring system with sub-second temporal resolution, Mini-MegaTORTORA (MMT-9), which is in operation now at Special Astrophysical Observatory on Russian Caucasus. The system is able to observe the sky simultaneously in either wide (˜900 square degrees) or narrow (˜100 square degrees) fields of view, either in clear light or with any combination of color (Johnson-Cousins B, V or R) and polarimetric filters installed, with exposure times ranging from 0.1 s to hundreds of seconds.The real-time system data analysis pipeline performs automatic detection of rapid transient events, both near-Earth and extragalactic. The objects routinely detected by MMT include faint meteors and artificial satellites.

  8. Deviation between navigated and final 3-dimensional implant position in mini-invasive unicompartmental knee arthroplasty: a pilot study in 13 patients.

    Science.gov (United States)

    Martinez-Carranza, Nicolas; Weidenhielm, Lars; Crafoord, Joakim; Hedström, Margareta

    2012-12-01

    Unicompartmental knee arthroplasty (UKA) is an established method of treating isolated gonartrosis. Modern techniques such as computer-assisted surgery (CAS) and minimally invasive surgery (MIS) are attractive complementary methods to UKA. However, the positioning of the components remains a concern. Thus, we performed a prospective study to assess whether there was deviation between the navigated implant position and the final implant position. We performed UKA with MIS and CAS in 13 patients. By comparing intraoperative navigation data with postoperative computed tomography (CT) measurements, we calculated the deviation between the computer-assisted implant position and the final 3-D implant position of the femoral and tibial components. The computer-assisted placement of the femoral and tibial component showed adequate position and consistent results regarding flexion-extension and varus-valgus. However, regarding rotation there was a large variation and 6 of 10 patients were outside the target range for both the femoral component and the tibial component. Difficulties in assessing anatomical landmarks with the CAS in combination with MIS might be a reason for the poor rotational alignment of the components.

  9. Primary fixation of mini slings: a comparative biomechanical study in vivo

    Directory of Open Access Journals (Sweden)

    Paulo Palma

    2012-04-01

    Full Text Available INTRODUCTION AND OBJECTIVES: The mini sling concept for stress urinary incontinence is an anatomical approach that involves placing a midurethral low-tension tape anchored to the obturator internus muscles bilaterally. They overcome the blind passage of long needles and all the related complications. There are many different devices available and because these are outpatient procedures, primary fixation plays an important role in the outcome. The objective is to evaluate the primary fixation of the various devices of attachment of the commercially available mini-slings through biomechanical tests. MATERIALS AND METHODS: A total of 45 Wistar rats were divided in 3 groups of 15 rats each. They underwent 5 subcutaneous implantation of different mini slings and one polipropilene mesh (control, as follows: TVT-Secur® (Gynecare, USA, Type 1 polypropylene mesh (control; Ophira Mini Sling System® (Promedon, Argentina, Tissue Fixation System® (TFS PTY, Australia, Zipper Sling® and "T device" (Prosurg, USA. The abdominal wall was removed on bloc at different times after implant for biomechanical evaluation, which consisted in application of unidirectional force to the extremity of the fixation system or mesh, until it was completely removed from the tissue using a tension meter (Nexygen 3.0 Universal Testing Machine - LLOYD Instruments. The force was measured in Newtons (N. RESULTS: There was significant difference in the resistance to extraction among the different fixation systems. At 7 days the Ophira Mini Sling System® presented the best fixation and "T dispositive" the worst. CONCLUSION: Ophira mini sling System® presented the best primary fixation at 7º, 14º and 30º days. The impact of this feature in the clinical setting needs to be verified.

  10. A clinical cephalometric study of mini-implant anchorage for en-masse retraction of eight maxillary anterior teeth%微种植体辅助整体内收上前牙段的头影测量

    Institute of Scientific and Technical Information of China (English)

    张华; 麦志辉; 卢红飞; 艾虹; 文冲

    2011-01-01

    目的:研究微种植体支抗在矫治上颌前突病例中整体内收上前牙段的应用.方法:选择5例上颌前突患者,拔除第二前磨牙,采用直丝弓矫治技术,辅以微种植体支抗同时整体内收前牙段(6个前牙及2个第一前磨牙),通过X线头影测量分析,观察矫治前后上颌骨软硬组织的变化.结果:上颌骨的变化轻微;切牙平均内收(4.6±1.5)mm,压低(0.8±1.1)mm,根尖后移(1.7±1.4)mm,切牙与腭平面的夹角减少(6.8±3.5)度;支抗磨牙水平前移(0.5±0.3)mm,没有出现明显的颌向伸长;上唇突度减少(2.0±0.9)mm,鼻唇角增大(3±2.4)度.结论:微种植体能提供稳定的支抗,同时整体内收上前牙段,最大限度避免支抗的丧失,改善上唇突度.%Aim: To Study the efficiency of mini-implants as intraoral anchorage units for en-masse retraction of the 6 maxillary anterior teeth and 2 first premolars after the second premolars are extracted. Methods: Five patients requiring high anchorage after extraction of the maxillary second premolars were selected for this study. Straight wire appliance and mini-implants were used for en-masse retraction, Horizontal , vertical, and angular positions of the maxillary ? Rst molar and central incisor were evaluated ceph-alometrically before and after orthodontic retraction. Results; The edge of upper incisors were retracted (4. 6 ±1. 5)mm and intruded (0. 8 ±1. L)mm, the root apex moved distally (1. 7 ± 1.4)mm. The maxillary first molars showed mesial movement of (0. 5 ±0. 3)mm. The nasolabial angle increased (3 ±2.4)° and the angle between upper incisor and PP-plane decreased (6. 8 ± 3. 5 ) °. Conclusion: Mini-implants are efficient for intraoral anchorage reinforcement for en-masse retraction and intrusion of maxillary anterior teeth.

  11. Retention systems for extraoral maxillofacial prosthetic implants: a critical review.

    Science.gov (United States)

    Cobein, M V; Coto, N P; Crivello Junior, O; Lemos, J B D; Vieira, L M; Pimentel, M L; Byrne, H J; Dias, R B

    2017-05-25

    We describe the techniques available for retention of implant-supported prostheses: bar-clips, O-rings, and magnets. We present reported preferences and, although this is limited by the heterogeneity of methods used and patients studied, we hope we have identified the best retention systems for maxillofacial prosthetic implants. If practitioners know the advantages and disadvantages of each system, they can choose the most natural and comfortable prosthesis. We searched the PubMed and Scopus databases, and restricted our search to papers published 2001-13. MeSH terms used were Maxillofacial prosthesis and Craniofacial prosthesis OR Craniofacial prostheses. We found a total of 2630 papers, and after duplicates had been removed we analysed the rest and found 25 papers for review. Of these, 12 were excluded because they were case reports or non-systematic reviews. Of the remaining 13, 10 described group analyses and seemed appropriate to find practitioner's choices, as cited in the abstract (n=1611 prostheses). Three papers did not mention the type of prosthetic connection used, so were excluded. The most popular choices for different conditions were analysed, though the sites and retention systems were not specified in all 10 papers. The bar-clip system was the most used in auricular (6/10 papers) and nasal prostheses (4/10). For the orbital region, 6/10 favoured magnets. Non-osseointegrated mechanical or adhesive retention techniques are the least expensive and have no contraindications. When osseointegrated implants are possible, each facial region has a favoured system. The choice of system is influenced by two factors: standard practice and the abilities of the maxillofacial surgeon and maxillofacial prosthetist. Copyright © 2017 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

  12. Effects of implant system, impression technique, and impression material on accuracy of the working cast.

    Science.gov (United States)

    Wegner, Kerstin; Weskott, Katharina; Zenginel, Martha; Rehmann, Peter; Wöstmann, Bernd

    2013-01-01

    This in vitro study aimed to identify the effects of the implant system, impression technique, and impression material on the transfer accuracy of implant impressions. The null hypothesis tested was that, in vitro and within the parameters of the experiment, the spatial relationship of a working cast to the placement of implants is not related to (1) the implant system, (2) the impression technique, or (3) the impression material. A steel maxilla was used as a reference model. Six implants of two different implant systems (Standard Plus, Straumann; Semados, Bego) were fixed in the reference model. The target variables were: three-dimensional (3D) shift in all directions, implant axis direction, and rotation. The target variables were assessed using a 3D coordinate measuring machine, and the respective deviations of the plaster models from the nominal values of the reference model were calculated. Two different impression techniques (reposition/pickup) and four impression materials (Aquasil Ultra, Flexitime, Impregum Penta, P2 Magnum 360) were investigated. In all, 80 implant impressions for each implant system were taken. Statistical analysis was performed using multivariate analysis of variance. The implant system significantly influenced the transfer accuracy for most spatial dimensions, including the overall 3D shift and implant axis direction. There was no significant difference between the two implant systems with regard to rotation. Multivariate analysis of variance showed a significant effect on transfer accuracy only for the implant system. Within the limits of the present study, it can be concluded that the transfer accuracy of the intraoral implant position on the working cast is far more dependent on the implant system than on the selection of a specific impression technique or material.

  13. Ion beam system for implanting industrial products of various shapes

    Science.gov (United States)

    Denholm, A. S.; Wittkower, A. B.

    1985-01-01

    Implantation of metals and ceramics with ions of nitrogen and other species has improved surface properties such as friction, wear and corrosion in numerous industrial applications. Zymet has built a production machine to take advantage of this process which can implant a 2 × 10 17 ions/cm 2 dose of nitrogen ions into a 20 cm × 20 cm area in about 30 min using a 100 keV beam. Treatment is accomplished by mounting the product on a cooled, tiltable, turntable which rotates continuously, or is indexed in 15° steps to expose different surfaces in fixed position. Product cooling is accomplished by using a chilled eutectic metal to mount and grip the variously shaped objects. A high voltage supply capable of 10 mA at 100 kV is used, and the equipment is microcomputer controlled via serial light links. All important machine parameters are presented in sequenced displays on a CRT. Uniformity of treatment and accumulated dose are monitored by a Faraday cup system which provides the microprocessor with data for display of time to completion on the process screen. For routine implants the operator requires only two buttons; one for chamber vacuum control, and the other for process start and stop.

  14. Wearable Wireless Telemetry System for Implantable BioMEMS Sensors

    Science.gov (United States)

    Simons, Rainee N.; Miranda, Felix A.; Wilson, Jeffrey D.; Simons, Renita E.

    2008-01-01

    Telemetry systems of a type that have been proposed for the monitoring of physiological functions in humans would include the following subsystems: Surgically implanted or ingested units that would comprise combinations of microelectromechanical systems (MEMS)- based sensors [bioMEMS sensors] and passive radio-frequency (RF) readout circuits that would include miniature loop antennas. Compact radio transceiver units integrated into external garments for wirelessly powering and interrogating the implanted or ingested units. The basic principles of operation of these systems are the same as those of the bioMEMS-sensor-unit/external-RFpowering- and-interrogating-unit systems described in "Printed Multi-Turn Loop Antennas for Biotelemetry" (LEW-17879-1) NASA Tech Briefs, Vol. 31, No. 6 (June 2007), page 48, and in the immediately preceding article, "Hand-Held Units for Short-Range Wireless Biotelemetry" (LEW-17483-1). The differences between what is reported here and what was reported in the cited prior articles lie in proposed design features and a proposed mode of operation. In a specific system of the type now proposed, the sensor unit would comprise mainly a capacitive MEMS pressure sensor located in the annular region of a loop antenna (more specifically, a square spiral inductor/ antenna), all fabricated as an integral unit on a high-resistivity silicon chip. The capacitor electrodes, the spiral inductor/antenna, and the conductor lines interconnecting them would all be made of gold. The dimensions of the sensor unit have been estimated to be about 110.4 mm. The external garment-mounted powering/ interrogating unit would include a multi-turn loop antenna and signal-processing circuits. During operation, this external unit would be positioned in proximity to the implanted or ingested unit to provide for near-field, inductive coupling between the loop antennas, which we have as the primary and secondary windings of an electrical transformer.

  15. Totally implantable hearing system: Five-year hearing results.

    Science.gov (United States)

    Shohet, Jack A; Kraus, Eric M; Catalano, Peter J; Toh, Elizabeth

    2017-04-13

    1) To provide long-term hearing outcome measures of a totally implantable hearing system (implant) and compare to the baseline unaided (BLU) and baseline aided (BLA) conditions, and 2) discuss relevant safety measures. Prospective, nonrandomized, multicenter, single-subject-as-own-control design. Fifty-one subjects with mild to severe sensorineural hearing loss were implanted between 2008 and 2009 and enrolled in this postmarket approval study in the setting of private and hospital-based practices. Forty-nine of these subjects completed the 5-year study, which included annual follow-ups. Primary effectiveness endpoints were speech reception threshold (SRT) and word recognition scores at 50 dB (WRS50s). Secondary effectiveness endpoints were WRSs and the Abbreviated Profile of Hearing Aid Benefit (APHAB) scores. Adverse Device Effects (ADEs) and Serious Adverse Device Effects (SADEs) reported during the study period and a comparison of bone conduction scores are submitted as safety measures. Compared to the BLA condition, 1) SRT scores were improved at every annual follow-up; 2) WRS50s were better in 49%, and the same in 41% at the 5-year follow-up; 3) WRSs were improved by 17% at the 5-year follow-up; and 4) APHAB scores were improved in most subscales at every annual follow-up. There were three SADEs in three subjects and 15 ADEs in 11 subjects. Bone conduction scores increased by 3.7 dB at the 5-year follow-up. Average battery life was 4.9 years. The implant compared favorably to the subjects' hearing aid throughout the 5-year period in all of the areas measured and was found to be safe. 2b Laryngoscope, 2017. © 2017 The American Laryngological, Rhinological and Otological Society, Inc.

  16. Renewable rural electrification. Sustainability assessment of mini-hybrid off-grid technological systems in the African context

    Energy Technology Data Exchange (ETDEWEB)

    Brent, Alan Colin [Resource Based Sustainable Development, Natural Resources and the Environment, CSIR, Stellenbosch (South Africa); Graduate School of Technology Management, University of Pretoria (South Africa); Rogers, David E. [Energy and Processes, Material Science and Manufacturing, CSIR, Pretoria (South Africa)

    2010-01-15

    The investigation summarised in this paper applied a sustainability assessment methodology on a renewable energy technological system in a rural village project that was commissioned by the South African Department of Minerals and Energy. The project comprised of wind, solar and lead-acid battery energy storage technologies that were implemented as a mini-hybrid off-grid electrification system for the village. The sustainability assessment methodology predicts the outcomes of such interventions by way of a learning model using discipline experts in the fields of economics, sociology, ecosystem sustainability, institutional governance, and the physics and chemistry of energy conversion processes. The comparison of the project's outcomes with a South African sustainable development framework shows that the specific village renewable off-grid electrification system is not viable. The main reason is that charges for electricity supply costs in village grids are too high for available subsidies; the economies of scale for renewable energy supply technologies favour national grids. The failure of the integrated system may also be attributable to the complexity of the social-institutional sub-system, which resulted in uncertainty for project planners and system designers, and the lack of resilience of the technological system to demands from the socio-economic and institutional sub-systems. Policy-related recommendations are made accordingly. (author)

  17. ROOTING MINI-CUTTINGS OF Paulownia fortunei var. mikado DERIVED FROM CLONAL MINI-GARDEN1

    Directory of Open Access Journals (Sweden)

    Carlos André Stuepp

    2015-06-01

    Full Text Available ABSTRACTWe aimed to evaluate the technical efficiency of mini-cuttings technique on vegetative propagation of Paulownia fortunei (Seem. Hemsl. var. Mikado, as well as the possible existence of anatomical barriers to its rooting. Therefore, plants originated from cuttings formed the mini-stumps and, consequently the clonal mini-garden, which was conducted in semi-hydroponic system. We evaluated the survival of mini-stumps and sprouts production for five successive collects, the percentage of mini-cuttings rooting and their anatomical description. The mini-cuttings were prepared with about 6 to 8 cm in length and two leaves reduced by about 50% in the upper third, being remained an area of, approximately 78 cm2 (10 cm diameter. The mini-cuttings were placed in tubes of 53 cm3, with substrate formed with fine vermiculite and carbonized rice hulls (1:1 v/v and rooted in acclimatized greenhouse. After 30 days we evaluated the percentage of rooted mini-cuttings, radicial vigor (number and length of roots / mini-cutting, callus formation, emission of new shoots and maintenance of the original leaves. The mini-stumps showed 100% survival after five collects and an average production of 76-114 mini-cuttings/m2/month and rooting ranged from 70 to 90%. Mini-cuttings technique is efficient in to propagate adult propagules of the species and there are not anatomical barriers preventing roots emission.

  18. Hybrid mini-grid systems – electricity for communities not connected to the national electricity grid based on renewable energy resources

    CSIR Research Space (South Africa)

    Szewczuk, S

    2008-11-01

    Full Text Available Africa’s first hybrid mini-grid energy system at the Hluleka Nature Reserve on the Wild Coast of the Eastern Cape province of South Africa. This paper describes the three-year investigative project in the Eastern Cape province, the formulation...

  19. Estudio de la osteointegración y posibles alteraciones provocadas por el empleo de implantes dentales en hueso inmaduro. Estudio experimental en mini pigs

    OpenAIRE

    2016-01-01

    El empleo de implantes dentales se ha convertido en práctica habitual en la odontología humana actual, siendo su empleo cada vez más frecuente. Esto es debido tanto a los buenos resultados, como a la reducción de costes de esta técnica, lo que permite un mayor acceso al público general. El cerdo ha sido utilizado como modelo experimental en muchos trabajos de investigación, tanto en medicina humana como veterinaria. Hay multitud de artículos publicados que hacen referencia a su utilización en...

  20. Cutaneous and systemic hypersensitivity reactions to metallic implants

    DEFF Research Database (Denmark)

    Basko-Plluska, Juliana L; Thyssen, Jacob P; Schalock, Peter C

    2011-01-01

    ) following the insertion of intravascular stents, dental implants, cardiac pacemakers, or implanted gynecologic devices. Despite repeated attempts by researchers and clinicians to further understand this difficult area of medicine, the association between metal sensitivity and cutaneous allergic reactions...

  1. Integrated electronic system for implantable sensory NFC tag.

    Science.gov (United States)

    Zaher, Ali; Saersten, Joar; Nguyen, Thanh Trung; Hafliger, Philipp

    2015-01-01

    We have designed the complete electronic system for an implanted sensory NFC-A tag (type 1) that monitors a physiological parameter, e.g. blood glucose, dehydration, bladder pressure, to name some of the target applications that we pursue. The tag is meant to be implanted under the skin and is powered by an NFC reader held close to it, such as a smart phone or a smart watch. The electronic system consists of a sensor front-end, ADC, NFC-A transceiver and NFC power harvester. In its present status, the physical layer of the communication and the power harvester have been implemented on one ASIC, and the sensor front-end and ADC on another, while the digital circuits realizing the higher level NFC protocol have been implemented on an FPGA. Simulations and a few preliminary test results are presented in this paper. The ultimate goal after thorough testing of this first prototype is to integrate all of these modules on a single ASIC.

  2. Cost comparison of individual and mini grid photovoltaic systems for rural electrification; Comparacao de custos entre sistemas fotovoltaicos individuais e minicentrais fotovoltaicas para eletrificacao rural

    Energy Technology Data Exchange (ETDEWEB)

    Soares, Guilherme Fleury Wanderley; Vieira, Leonardo dos Santos Reis; Galdino, Marco Antonio Esteves [Centro de Pesquisas de Energia Eletrica (CEPEL), Rio de Janeiro, RJ (Brazil)], Emails: fleury@cepel.br, lsrv@cepel.br, marcoag@cepel.br; Olivieri, Marta Maria de Almeida; Borges, Eduardo Luis de Paula; Carvalho, Claudio Monteiro de; Lima, Alex Artigiani Neves [Centrais Eletricas Brasileiras S.A. (ELETROBRAS), Rio de Janeiro, RJ (Brazil)], Emails: martaolivieri@eletrobras.com, eduardo_borges@eletrobras.com, claudio.carvalho@eletrobras.com, alex.lima@eletrobras.com

    2010-07-01

    A cost comparison for individual and mini grid photovoltaic systems is made regarding the use of these systems for rural electrification in Northern Brazil. The estimates for maintenance costs were based on existing experience for individual systems already operating in the region. A comparison was also made between modified automotive lead acid batteries commonly used in photovoltaic systems in Brazil and the much more expensive OPzS tubular types. The results of these evaluations show that the maintenance costs are expected to be lower in the case of the mini grids than in individual systems. This is because for a given number of houses to be supplied with electrical energy, they use a smaller number of components subject to failures, like inverters and charge controllers. OPzS batteries are expected to compensate for their higher prices if their predicted operating lifetime can be confirmed under the practical conditions envisaged. (author)

  3. A pragmatic performance reporting approach for describing PV Hybrid systems within mini-grids. Work in progress from IEA's PVPS Task 11 Act. 31

    Energy Technology Data Exchange (ETDEWEB)

    Swingler, Andrew [Schneider Electric, Burnaby, BC (Canada). Renewable Energies Business

    2010-07-01

    Reviewers of available PV hybrid system and mini-grid case studies are often limited to information detailing the size of the main system components (PV, battery and generator) and perhaps some historical anecdotes recalling major maintenance activities. While this enables rapid insight into the capital cost and perhaps the overall reliability of the system, this information communicates little in the way of system performance from a levelized cost of electricity and GHG emissions point of view - or what can be considered 'the business' perspective. Key system performance information must be available to effectively communicate operational system performance so system operators or perspective customers. Activity 31 of the IEA's PVPS Task 11 looks at how performance reporting can be useful, why it is often absent and what can be done to improve the current situation. This paper reviews some past work in the area of data acquisition and performance calculation used for describing PV Hybrid and mini-grid systems. In particular the IEC 61724 PV performance monitoring standard and results from the 'Benchmarking RE Components and Systems' project are considered. Ultimately, a stripped-down, easier-to-implement and flexible method for monitoring and reporting on key performance indicators is proposed based, in part, on the prior literature. The proposed framework is then used to briefly discuss the performance of two monitored PV hybrid mini-grid examples. (orig.)

  4. Subcutaneous Achilles tendon rupture: A comparison between open technique and mini-invasive tenorrhaphy with Achillon(®) suture system.

    Science.gov (United States)

    Daghino, W; Enrietti, E; Sprio, A E; di Prun, N Barbasetti; Berta, G N; Massè, A

    2016-11-01

    Surgical management of Achilles tendon rupture is still controversial: open techniques have a higher rate of soft tissue complications but a lower incidence of re-rupture than percutaneous tenorrhaphies. The aim of our retrospective study was to analyze and compare clinical and functional results in patients treated with either the conventional open or minimally invasive suture treatment with the Achillon(®) system. A retrospective review of 140 patients was performed; 72 were treated with open tenorrhaphy, 68 with the minimally invasive Achillon(®) suture system. With a comparable re-rupture rate, there was a statistically significant reduction in surgical time, incidence of minor complications, time required to return to sport activities and return to work in the minimally invasive group. Achillon(®) mini-invasive suture system is a reliable tool for the Achilles tendon ruptures, able to reduce the incidence of soft tissues complications if compared to the classic open tenorrhaphy, while maintaining strength of the suture and leading to superimposed functional outcomes. Copyright © 2016 Elsevier Ltd. All rights reserved.

  5. Perioperative Systemic Inflammatory Response following Robot-Assisted Laparoscopic Cystectomy vs. Open Mini-Laparotomy Cystectomy: A Prospective Study.

    Science.gov (United States)

    Skjold Kingo, Pernille; Palmfeldt, Johan; Nørregaard, Rikke; Borre, Michael; Jensen, Jørgen Bjerggaard

    2017-07-01

    Surgeries, such as radical cystectomy (RC), induce a systemic inflammatory response (SIR). SIR plays an important role in controlling the human immune system. This study aims at comparing the SIR in robot-assisted laparoscopic cystectomy (RALC) to open mini-laparotomy cystectomy (OMC) with a urinary diversion (UD). Comparison was based on immunologic markers of SIR, thus quantifying the degree of tissue trauma. Forty-two male patients underwent RC with an ileal conduit. Either OMC RC (OMC; n = 20), RALC with extracorporeal UD (RALC-EUD; n = 13), or RALC with intracorporeal UD (RALC-IUD; n = 9) was performed. Blood samples were obtained preoperatively (PREOP), immediately after surgery (POD0), 24 (POD1) and 48 h (POD2) postoperatively. Clinical parameters were collected from medical records. Estimated blood loss and blood transfusion volume was higher in OMC (p's OMC (p = 0.016). IL-10 level was higher at POD0 (p = 0.029) and POD1 (p = 0.038) in OMC vs. RALC-EUD. MCP-1 levels for RALC-IUD were significantly lower compared to RALC-EUD (p = 0.027). This study found that postoperative SIR was overall less pronounced in RALC, thus depicting reduced tissue trauma. No major clinical differences between RALC-IUD and -EUD were found. © 2017 S. Karger AG, Basel.

  6. Nickel-induced systemic contact dermatitis and intratubal implants: the baboon syndrome revisited.

    Science.gov (United States)

    Bibas, Nathalie; Lassere, Jacques; Paul, Carle; Aquilina, Christian; Giordano-Labadie, Françoise

    2013-01-01

    Permanent sterilization using intratubal implants is becoming increasingly popular worldwide. We report the first case of a 40-year-old woman presenting a systemic contact dermatitis due to nickel-containing intratubal implants: the Essure system. The diagnosis was confirmed with positive patch test result for nickel and total clearance of dermatitis after removing the implants that contain a metallic spiral of nitinol (alloy of 55% nickel and 45% titanium). Systemic contact dermatitis to the intratubal implants could be explained by the corrosion of nitinol after implantation resulting in the release of nickel. In the literature, no similar case has been reported despite the introduction of intratubal implants since 2002. Dermatologists and gynecologists need to be aware of this type of complication. In practice, a thorough assessment for possible nickel contact dermatitis in a woman undergoing sterilization with Essure is recommended. Preoperative patch testing must be carried out if there is any doubt.

  7. Outcome analysis in 3,160 implantations of radiologically guided placements of totally implantable central venous port systems

    Energy Technology Data Exchange (ETDEWEB)

    Teichgraeber, Ulf K.M. [Charite University Hospital, Department of Radiology, Berlin (Germany); Charite Universitaetsmedizin Berlin, Institut fuer Diagnostische und Interventionelle Radiologie, Berlin (Germany); Kausche, Stephan; Nagel, Sebastian N.; Gebauer, Bernhard [Charite University Hospital, Department of Radiology, Berlin (Germany)

    2011-06-15

    In this retrospective study the success and complication rates after radiologically guided port catheter implantation were evaluated. Between 2000 and 2008, 3,160 port catheter systems were implanted in our interventional suite. All interventions were imaging guided. The puncture of the preferably right internal jugular vein (IJV) was ultrasound-assisted and the catheter tip position was controlled with fluoroscopy. Catheter indwelling time and rates of periprocedural, early and late complications were evaluated. 922,599 catheter days (mean, 292 days; range, 0-2,704 days) were documented. The implantation was successful in 3,153 (99.8%) cases. A total of 374 (11.8%; 0.41/1,000 catheter days) adverse events were recorded. Of these, 42 (1.33%) were periprocedural complications. 86 (3.3%; 0.09/1,000 catheter days) early and 246 (9.4%; 0.27/1,000 catheter days) late onset complications occurred after port implantation. The most common complications were blood stream infection (n = 134; 5.1%; 0.15/1,000 catheter days), catheter-induced venous thrombosis (n = 97; 3.7%; 0.11/1,000 catheter days) and catheter migration (n = 34; 1.3%; 0.04/1,000 catheter days). A total of 193 (6.1%) port explantations were required. Ultrasound guided port implantation via the IJV results in low periprocedural complication rates. (orig.)

  8. Mini lathe machine converted to CNC

    Directory of Open Access Journals (Sweden)

    Alexandru Morar

    2012-06-01

    Full Text Available This paper presents the adaptation of a mechanical mini-lathing machine to a computerized numerical control (CNC lathing machine. This machine is composed of a ASIST mini-lathe and a two-degrees-of-freedom XZ stage designed specifically for this application. The whole system is controlled from a PC using adequate CNC control software.

  9. The Mini Space Farm—A Food Regenerative System in the Long-term Manned Space Mission.

    Science.gov (United States)

    Zhang, Mao

    In this invention we propose rearing six types of small animals which are mainly insects, all the biological wastes (bio-waste) in the space human life environment, including the human and animal feces, inedible parts of the plants and animals, food bits and other bio-wastes,can be feedstuff for rearing these six small animals, each one can recycle and digest the specific wastes to be their nourishing biomass. The biomass of these six animals, combine with the inedible parts of the space plants, will further be used as feedstuff for feeding edible animals of poultry, aquatics, amphibians, even the livestock. The meat, egg and milk from these edible animals are taken as human's animal food. Here we name these animals are as Edible Animal (EA), these six small animals are as Recycling Animals (RA). The water and nutrition left in the residues after rearing the RA can be recycled again by other RA or used to fertilize the space plants. The appropriate space plants include both terrestrial and aquatic species, such as vegetable,grain,feeding plant,edible algae and germs,also be cultivated as vegetarian food which have already successfully developed by NASA and other countries. These RA have strong reproduction ability, short life cycle, rich of nutrition, and can be easily reared in high densities with high efficiency in microgravity. Like the RA, the EA and space plants, they can be continuously reared in cages,boxes and water tanks as the solid manner, their optimal growth temperature and the humidity are same with RA, so they can be fed in the same cabin. Rearing RA, EA and plants together can provide a self-sustaining food system with minimum volume, weight, energy, labor and cost, which is the basis for realizing mini space farm in long term manned space missions. In this way, two kinds of mini space farm models have been designed: A cabin model to be used on ISS and flight craft functioning within a microgravity environment, and a greenhouse model to be used on

  10. Dental implants in the diabetic patient: systemic and rehabilitative considerations.

    Science.gov (United States)

    Michaeli, Eli; Weinberg, Ido; Nahlieli, Oded

    2009-09-01

    Diabetes mellitus is the most prevalent endocrine disease, comprising the third highest cause of disability and morbidity in the Western world. In the past, implant placement was contraindicated in diabetic patients because of increased risk for implant failure and infection. Publications in recent years have shown success rates for dental implants in diabetic patients resembling those of the general population. Other studies, in diabetic patients, as well as in animal models, have shown an increased risk for implant failure. These results raise the question of whether diabetic patients are suitable for dental implant rehabilitation. This article reviews the literature and presents the factors used in assessing the severity of diabetes and its complications, as well as the considerations for rehabilitation planning in these patients. Integration of these factors by the dentist dictates whether as well as what type of implant-supported restoration should be preformed.

  11. Ion implantation system and process for ultrasensitive determination of target isotopes

    Energy Technology Data Exchange (ETDEWEB)

    Farmer, III, Orville T.; Liezers, Martin

    2016-09-13

    A system and process are disclosed for ultrasensitive determination of target isotopes of analytical interest in a sample. Target isotopes may be implanted in an implant area on a high-purity substrate to pre-concentrate the target isotopes free of contaminants. A known quantity of a tracer isotope may also be implanted. Target isotopes and tracer isotopes may be determined in a mass spectrometer. The present invention provides ultrasensitive determination of target isotopes in the sample.

  12. Influence of platelet-rich plasma on dental implants. Osseointegration in well-controlled diabetic patients.

    Science.gov (United States)

    Malik, A; Shaari, R; Rahman, S A; Aljuboori, M J

    2012-12-01

    The purpose of this study is to evaluate the effect of platelet-rich plasma (PRP) on the osseointegration of dental implants in diabetic patients. A split-mouth design was employed in all 14 patients, with each patient receiving two mini implants. A PRP-coated mini implant was installed in one quadrant as a trial and a plain mini implant was added in the opposite quadrant to serve as a control. Radiographic evaluation was done at 3, 6, and 9 weeks after implant placement. Radiographic density is measured at five points around the implants, repeatedly. Results showed no statistically significant difference between the two groups of implants. The minimally invasive mini implants successfully maintained integration at the end of 9 weeks. There were no cases of implant failure. The results of this study suggest that platelet-rich plasma implant coating has no significant effect in reducing the time for mini implant osseointegration in diabetic patients.

  13. Techno-economic analysis of a hybrid mini-grid system for Fiji islands

    Energy Technology Data Exchange (ETDEWEB)

    Lal, Sandeep; Raturi, Atul [Univ. of South Pacific, Suva (Fiji). School of Engineering and Physics

    2012-07-01

    The Pacific Island Countries constantly struggle with the challenges of high petroleum dependence for their electricity production and lack of adequate energy services. It is possible to alleviate the energy poverty by utilizing abundant renewable energy resources available in the region. The objective of this work is to investigate the feasibility of a wind/solar photovoltaic/diesel generator-based hybrid power system in a remote location in Fiji islands. We used the Hybrid Optimisation Model for Electric Renewables (HOMER) software to simulate the system and perform system optimisation analysis. The system characteristics were studied in terms of optimal configuration, net present cost and the cost of energy. An entirely renewable energy-based configuration is feasible if 10% annual capacity shortage is allowed, while for a scenario with no capacity shortage, addition of a diesel generator is necessary. The addition of renewable energy components results in greenhouse gas reduction which could be used for carbon trading. (orig.)

  14. Intraoperative implant rod three-dimensional geometry measured by dual camera system during scoliosis surgery.

    Science.gov (United States)

    Salmingo, Remel Alingalan; Tadano, Shigeru; Abe, Yuichiro; Ito, Manabu

    2016-05-12

    Treatment for severe scoliosis is usually attained when the scoliotic spine is deformed and fixed by implant rods. Investigation of the intraoperative changes of implant rod shape in three-dimensions is necessary to understand the biomechanics of scoliosis correction, establish consensus of the treatment, and achieve the optimal outcome. The objective of this study was to measure the intraoperative three-dimensional geometry and deformation of implant rod during scoliosis corrective surgery.A pair of images was obtained intraoperatively by the dual camera system before rotation and after rotation of rods during scoliosis surgery. The three-dimensional implant rod geometry before implantation was measured directly by the surgeon and after surgery using a CT scanner. The images of rods were reconstructed in three-dimensions using quintic polynomial functions. The implant rod deformation was evaluated using the angle between the two three-dimensional tangent vectors measured at the ends of the implant rod.The implant rods at the concave side were significantly deformed during surgery. The highest rod deformation was found after the rotation of rods. The implant curvature regained after the surgical treatment.Careful intraoperative rod maneuver is important to achieve a safe clinical outcome because the intraoperative forces could be higher than the postoperative forces. Continuous scoliosis correction was observed as indicated by the regain of the implant rod curvature after surgery.

  15. Mini-review: high rate algal ponds, flexible systems for sustainable wastewater treatment.

    Science.gov (United States)

    Young, P; Taylor, M; Fallowfield, H J

    2017-06-01

    Over the last 20 years, there has been a growing requirement by governments around the world for organisations to adopt more sustainable practices. Wastewater treatment is no exception, with many currently used systems requiring large capital investment, land area and power consumption. High rate algal ponds offer a sustainable, efficient and lower cost option to the systems currently in use. They are shallow, mixed lagoon based systems, which aim to maximise wastewater treatment by creating optimal conditions for algal growth and oxygen production-the key processes which remove nitrogen and organic waste in HRAP systems. This design means they can treat wastewater to an acceptable quality within a fifth of time of other lagoon systems while using 50% less surface area. This smaller land requirement decreases both the construction costs and evaporative water losses, making larger volumes of treated water available for beneficial reuse. They are ideal for rural, peri-urban and remote communities as they require minimum power and little on-site management. This review will address the history of and current trends in high rate algal pond development and application; a comparison of their performance with other systems when treating various wastewaters; and discuss their potential for production of added-value products. Finally, the review will consider areas requiring further research.

  16. The locomotor system as seen in Brazilian scientific journals: a mini review

    Directory of Open Access Journals (Sweden)

    Mauricio Rocha e Silva

    2010-01-01

    Full Text Available OBJECTIVE: To make recent selected publications on the locomotor system available to the readership of Clinics. METHOD: A general survey of articles published in selected Brazilian journals was inspected and 91 articles were critically analyzed. They were categorized and briefly described. A final summary of themes is reproduced here. RESULTS: Papers fall into two main categories: articular and muscular pathology and therapeutics; medical sports. A number of papers are not classifiable under these headings. CONCLUSION: The locomotor system has been extensively analyzed and discussed in the Brazilian scientific press in recent years. Not surprisingly, knee and ankle pathology, soccer and running are dominant themes.

  17. A fully integrated microbattery for an implantable microelectromechanical system

    Energy Technology Data Exchange (ETDEWEB)

    Albano, F. [Department of Material Science Engineering, University of Michigan, Ann Arbor, MI 48109 (United States); Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI 48109 (United States); Lin, Y.S.; Blaauw, D.; Sylvester, D.M. [Department of Electrical Engineering and Computer Science, University of Michigan, Ann Arbor, MI 48109 (United States); Wise, K.D. [Department of Electrical Engineering and Computer Science, University of Michigan, Ann Arbor, MI 48109 (United States); Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109 (United States); Sastry, A.M. [Department of Material Science Engineering, University of Michigan, Ann Arbor, MI 48109 (United States); Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109 (United States); Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI 48109 (United States)

    2008-12-01

    The Wireless Integrated Microsystems Engineering Research Center's Intraocular Sensor (WIMS-ERC IOS) was studied as a model system for an integrated, autonomous implantable device. In the present study, we had four objectives: (1) select and designing an optimized power supply for the WIMS-IOS; (2) develop a fabrication technique allowing small scale, low-cost, and integrable fabrication for CMOS systems, and experimentally demonstrate a microscopic power source; (3) map capacity and lifetime of several fabricated microbatteries; (4) determine the effects of miniaturization on capacity, lifetime and device architecture. Physical vapor deposition (PVD) was used to deposit thin layers ({<=}1 {mu}m) of metal sequentially onto glass substrates (SiO{sub 2}, as used in the device). To map the influence of size over cell capacity and cycle life, we fabricated and tested five stand-alone cells using a Solartron {sup registered} 1470E battery tester and a Maccor {sup registered} 4000 series tester. A sixth battery was fabricated to investigate the effects of system integration, variable discharge rate and size reduction simultaneously. The highest experimental capacity among the larger cells O(cm{sup 2}) was 100 {mu}Ah, achieved by IOS-C-1 at 250 {mu}A (1.4 C) discharge. Among O(mm{sup 2}) cells, IOS-M-1 achieved the highest capacity (2.75 {mu}Ah, {proportional_to}76% of theoretical) at 2.5 {mu}A discharge (0.7 C rate). (author)

  18. Design and implementation of a embedded USB MiniHost system%一种嵌入式USB MiniHost系统设计与实现

    Institute of Scientific and Technical Information of China (English)

    梁宝娟; 孙少波

    2012-01-01

    设计并实现了一个嵌入式USB主机系统的硬件和软件,用于解决USB设备不能脱离PC主机的问题。并在设计的硬件和软件基础上利用嵌入式C语言编制了具有USBHost功能通用固件库。并利用这个固件库实现一个具有并口到USB接口的打印转换器。%A embedded USB host system is designed, including hardware and software to solve the problem that embedded systems are not able to make use of USB devices. Programmed a common firmware library with USB host function using embedded C language And illustrates how to fulfill the USB device class program with a USB printer is the target device to be used.

  19. Output mini-max control for polynomial systems: analysis and applications

    Science.gov (United States)

    Jiménez-Lizárraga, Manuel; Basin, Michael V.; Rodríguez Carreón, Victoria Celeste; Rodríguez Ramírez, Pablo Cesar

    2014-09-01

    This paper presents a solution to a robust optimal regulation problem for a nonlinear polynomial system affected by parametric and matched uncertainties, which is based only on partial state information. The parameters describing the dynamics of the nonlinear polynomial plant depend on a vector of unknown parameters, which belongs to a finite parametric set, and the application of a certain control input is associated with the worst or least favourable value of the unknown parameter. A high-order sliding mode state reconstructor is designed for the nonlinear plant in such a way that the previously designed control can be applied for a system with incomplete information. Additionally, the matched uncertainty is also compensated by means of the same output-based regulator. The obtained algorithm is applied to control an uncertain nonlinear inductor circuit of the third order and a mechanical pendulum of the third order, successfully verifying the effectiveness of the developed approach.

  20. Mini-review: novel non-destructivein situbiofilm characterization techniques in membrane systems

    KAUST Repository

    Valladares Linares, R.

    2016-05-12

    Membrane systems are commonly used in the water industry to produce potable water and for advanced wastewater treatment. One of the major drawbacks of membrane systems is biofilm formation (biofouling), which results in an unacceptable decline in membrane performance. Three novel in situ biofouling characterization techniques were assessed: (i) optical coherence tomography (OCT), (ii) planar optodes, and (iii) nuclear magnetic resonance (NMR). The first two techniques were assessed using a biofilm grown on the surface of nanofiltration (NF) membranes using a transparent membrane fouling simulator that accurately simulates spiral wound modules, modified for in situ biofilm imaging. For the NMR study, a spiral wound reverse osmosis membrane module was used. Results show that these techniques can provide information to reconstruct the biofilm accurately, either with 2-D (OCT, planar optodes and NMR), or 3-D (OCT and NMR) scans. These non-destructive tools can elucidate the interaction of hydrodynamics and mass transport on biofilm accumulation in membrane systems. Oxygen distribution in the biofilm can be mapped and linked to water flow and substrate characteristics; insights on the effect of crossflow velocity, flow stagnation, and feed spacer presence can be obtained, and in situ information on biofilm structure, thickness, and spatial distribution can be quantitatively assessed. The combination of these novel non-destructive in situ biofilm characterization techniques can provide real-time observation of biofilm formation at the mesoscale. The information obtained with these tools could potentially be used for further improvement in the design of membrane systems and operational parameters to reduce impact of biofouling on membrane performance. © 2016 Balaban Desalination Publications. All rights reserved.

  1. MINI-REVIEW: SYSTEMIC LUPUS ERYTHEMATOSUS AND DEFICIENCIES OF EARLY COMPONENTS OF THE COMPLEMENT CLASSICAL PATHWAY

    Directory of Open Access Journals (Sweden)

    Lourdes eIsaac

    2016-02-01

    Full Text Available The complement system plays an important role in the innate and acquired immune response against pathogens. It consists of more than 30 proteins found in soluble form or attached to cell membranes. Most complement proteins circulate in inactive forms and can be sequentially activated by the Classical, Alternative or Lectin Pathways. Biological functions such as opsonization, removal of apoptotic cells, adjuvant function, activation of B lymphocytes, degranulation of mast cells and basophils, solubilization and clearance of immune complex and cell lysis are dependent on complement activation. Although the activation of the complement system is important to avoid infections, it also can contribute to the inflammatory response triggered by immune complex deposition in tissues in auto-immune diseases. Paradoxically, the deficiency of early complement proteins from the Classical Pathway is strongly associated with development of systemic lupus erythematous (SLE - mainly C1q deficiency (93% and C4 deficiency (75%. The aim of this review is to focus on the deficiencies of early components of the Classical Pathway (C1q, C1r, C1s, C4, C2 proteins in SLE patients.

  2. The Influence of Palatable Diets in Reward System Activation: A Mini Review

    Directory of Open Access Journals (Sweden)

    Isabel Cristina de Macedo

    2016-01-01

    Full Text Available The changes in eating patterns that have occurred in recent decades are an important cause of obesity. Food intake and energy expenditure are controlled by a complex neural system involving the hypothalamic centers and peripheral satiety system (gastrointestinal and pancreatic hormones. Highly palatable and caloric food disrupts appetite regulation; however, palatable foods induce pleasure and reward. The cafeteria diet is such a palatable diet and has been shown consistently to increase body weight and induce hyperplasia in animal obesity models. Moreover, palatable high-fat foods (such as those of the cafeteria diet can induce addiction-like deficits in brain reward function and are considered to be an important source of motivation that might drive overeating and contribute to the development of obesity. The mechanism of neural adaptation triggered by palatable foods is similar to those that have been reported for nondrug addictions and long-term drug use. Thus, this review attempts to describe the potential mechanisms that might lead to highly palatable diets, such as the cafeteria diet, triggering addiction, or compulsion through the reward system.

  3. Artrodese da coluna lombossacra com o implante A-Systems Lumbosacral column arthtodesis with a system's implant

    Directory of Open Access Journals (Sweden)

    Afrane Serdeira

    2004-12-01

    Full Text Available Foram avaliados 40 pacientes com espondilolistese e instabilidade lombossacra: 13 pacientes do tipo ístmica-lítica, 19 do tipo degenerativa, 2 pacientes do tipo traumática, 1 tipo do patológica, e 5 do tipo cirúrgica, nos quais foram realizadas 40 artrodeses da coluna lombossacra com enxerto ósseo e fixação metálica com o implante A-Systems. A avaliação dos pacientes foi realizada clínica e radiograficamente, nos períodos pré-operatório, pós-operatório imediato e pós-operatório tardio. O tempo de acompanhamento clínico máximo foi de 46 meses, o mínimo de 10 meses, obtendo-se um acompanhamento médio de 11 meses. A avaliação global tanto do ponto vista do paciente como da equipe médica mostrou que: 36 (90% dos pacientes obtiveram bom resultado; três pacientes (7,5% apresentaram melhora em relação ao pré-operatório e um paciente (2,5% não obteve melhora. Vinte e nove pacientes (72,5% tiveram sua capacidade de trabalho normalizada, nove (22,5% pacientes tiveram sua capacidade melhorada em 75% e dois (5% pacientes tiveram a capacidade melhorada em 50%. Vinte e um pacientes (52,5% tiveram o índice de Prolo aumentado entre 9 e 10 (excelente; 14 (35% tiveram índice de Prolo aumentado para 7 e 8 (bom; em 5 (12,5% o índice ficou entre 5 e 6 (regular e nenhum paciente teve índice 2, 3 ou 4 (mau. O tempo médio de retorno para as atividades normais variou de três a doze meses, com uma média de sete meses. Em comparação com métodos similares relatados pela literatura, o implante mostrou-se tão eficiente quanto eles, com as vantagens da simplicidade, da possibilidade de ser usado em vários níveis e da rigidez após montado.Lumbosacral column arthrodesis with bone graft and metallic fixation (A-Systems implant was carried out in 40 patients with spondylolisthesis and lumbosacral instability of the following types: isthmic-lytic in 13, degenerative in 19, traumatic in 2, pathological in 1, and surgical in 5

  4. Replacing worn overdenture abutments of an unknown implant system by using laser welding: a clinical report.

    Science.gov (United States)

    Mohunta, Vrinda V; Stevenson, James A; Lee, Damian J

    2014-09-01

    This clinical report describes a procedure for replacing worn ball abutments with low-profile resilient abutments by using laser welding when the implant system for a mandibular implant-supported overdenture could not be identified. Copyright © 2014 Editorial Council for the Journal of Prosthetic Dentistry. Published by Elsevier Inc. All rights reserved.

  5. An implantable thermoresponsive drug delivery system based on Peltier device.

    Science.gov (United States)

    Yang, Rongbing; Gorelov, Alexander V; Aldabbagh, Fawaz; Carroll, William M; Rochev, Yury

    2013-04-15

    Locally dropping the temperature in vivo is the main obstacle to the clinical use of a thermoresponsive drug delivery system. In this paper, a Peltier electronic element is incorporated with a thermoresponsive thin film based drug delivery system to form a new drug delivery device which can regulate the release of rhodamine B in a water environment at 37 °C. Various current signals are used to control the temperature of the cold side of the Peltier device and the volume of water on top of the Peltier device affects the change in temperature. The pulsatile on-demand release profile of the model drug is obtained by turning the current signal on and off. The work has shown that the 2600 mAh power source is enough to power this device for 1.3 h. Furthermore, the excessive heat will not cause thermal damage in the body as it will be dissipated by the thermoregulation of the human body. Therefore, this simple novel device can be implanted and should work well in vivo.

  6. Sucrose esters as natural surfactants in drug delivery systems--a mini-review.

    Science.gov (United States)

    Szűts, Angéla; Szabó-Révész, Piroska

    2012-08-20

    Sucrose esters (SEs) are widely used in the food and cosmetic industries and there has recently been great interest in their applicability in different pharmaceutical fields. They are natural and biodegradable excipients with well-known emulsifying and solubilizing behavior. Currently the most common pharmaceutical applications of SEs are for the enhancement of drug dissolution and drug absorption/permeation, and in controlled-release systems. Although the number of articles on SEs is continuously increasing, they have not yet been widely used in the pharmaceutical industry. The aim of this review is to discuss and summarize some of the findings and applications of SEs in different areas of drug delivery. The article highlights the main properties of SEs and focuses on their use in pharmaceutical technology and on their regulatory and toxicological status. Copyright © 2012 Elsevier B.V. All rights reserved.

  7. Mini-channel evaporator/heat pipe assembly for a chip cooling vapor compression refrigeration system

    Energy Technology Data Exchange (ETDEWEB)

    Ribeiro, Guilherme B.; Barbosa, Jader R. Jr.; Prata, Alvaro T. [Polo - Research Laboratories for Emerging Technologies in Cooling and Thermophysics, Department of Mechanical Engineering, Campus Universitario, Trindade, Federal University of Santa Catarina, Florianopolis, SC 88040900 (Brazil)

    2010-11-15

    We investigate a novel evaporator design for a small-scale refrigeration system whose function is to assist the existing heat pipe technology currently used in chip cooling of portable computers. A heat transfer model for the evaporator/heat pipe assembly was devised specifically for sizing the evaporator in order to keep the chip surface temperature below a certain value. A prototype was tested with R-600a at saturation temperatures of 45 and 55 C, mass flow rates between 0.5 and 1.5 kg h{sup -1} and heat transfer rates between 30 and 60 W. The experimental results demonstrated that the average refrigerant-side heat transfer coefficient is more sensitive to a change in the refrigerant mass flux than to changes in the saturation temperature and heat transfer rate. The agreement between the calculated heat transfer coefficient and the data was within {+-}10% for the conditions evaluated. (author)

  8. Implant Surface Temperature Changes during Er:YAG Laser Irradiation with Different Cooling Systems.

    Directory of Open Access Journals (Sweden)

    Abbas Monzavi

    2014-04-01

    Full Text Available Peri-implantitis is one of the most common reasons for implant failure. Decontamination of infected implant surfaces can be achieved effectively by laser irradiation; although the associated thermal rise may cause irreversible bone damage and lead to implant loss. Temperature increments of over 10ºC during laser application may suffice for irreversible bone damage.The purpose of this study was to evaluate the temperature increment of implant surface during Er:YAG laser irradiation with different cooling systems.Three implants were placed in a resected block of sheep mandible and irradiated with Er:YAG laser with 3 different cooling systems namely water and air spray, air spray alone and no water or air spray. Temperature changes of the implant surface were monitored during laser irradiation with a K-type thermocouple at the apical area of the fixture.In all 3 groups, the maximum temperature rise was lower than 10°C. Temperature changes were significantly different with different cooling systems used (P<0.001.Based on the results, no thermal damage was observed during implant surface decontamination by Er:YAG laser with and without refrigeration. Thus, Er:YAG laser irradiation can be a safe method for treatment of periimplantitis.

  9. Enzyme Stability and Activity in Non-Aqueous Reaction Systems: A Mini Review

    Directory of Open Access Journals (Sweden)

    Shihui Wang

    2016-02-01

    Full Text Available Enormous interest in biocatalysis in non-aqueous phase has recently been triggered due to the merits of good enantioselectivity, reverse thermodynamic equilibrium, and no water-dependent side reactions. It has been demonstrated that enzyme has high activity and stability in non-aqueous media, and the variation of enzyme activity is attributed to its conformational modifications. This review comprehensively addresses the stability and activity of the intact enzymes in various non-aqueous systems, such as organic solvents, ionic liquids, sub-/super-critical fluids and their combined mixtures. It has been revealed that critical factors such as Log P, functional groups and the molecular structures of the solvents define the microenvironment surrounding the enzyme molecule and affect enzyme tertiary and secondary structure, influencing enzyme catalytic properties. Therefore, it is of high importance for biocatalysis in non-aqueous media to elucidate the links between the microenvironment surrounding enzyme surface and its stability and activity. In fact, a better understanding of the correlation between different non-aqueous environments and enzyme structure, stability and activity can contribute to identifying the most suitable reaction medium for a given biotransformation.

  10. Mini Review: circular RNAs as potential clinical biomarkers for disorders in the central nervous system

    Directory of Open Access Journals (Sweden)

    Dan eLu

    2016-04-01

    Full Text Available Circular RNAs (circRNAs are a type of noncoding RNAs (ncRNAs, produced in eukaryotic cells during post-transcriptional processes. They are more stable than linear RNAs, and possess spatio-temporal properties. CircRNAs do not distribute equally in the neuronal compartments in the brain, but largely enriched in the synapses. These ncRNA species can be used as potential clinical biomarkers in complex disorders of the central nervous system (CNS, which is supported by recent findings. For example, ciRS-7 was found to be a natural microRNAs sponge for miRNA-7 and regulate Parkinson’s disease (PD/ Alzheimer’s disease (AD-related genes; circPAIP2 is an intron-retaining circRNA which upregulates memory-related parental genes PAIP2 to affect memory development through PABP reactivation. The quantity of circRNAs carry important messages, either when they are inside the cells, or in circulation, or in exosomes released from synaptoneurosomes and endothelial. In addition, small molecules such as microRNAs and microvesicles can pass through the blood-brain barrier (BBB and get into blood. For clinical applications, the study population needs to be phenotypically well-defined. CircRNAs may be combined with other biomarkers and imaging tools to improve the diagnostic power.

  11. Cutaneous and systemic hypersensitivity reactions to metallic implants

    DEFF Research Database (Denmark)

    Basko-Plluska, Juliana L; Thyssen, Jacob P; Schalock, Peter C

    2011-01-01

    Cutaneous reactions to metal implants, orthopedic or otherwise, are well documented in the literature. The first case of a dermatitis reaction over a stainless steel fracture plate was described in 1966. Most skin reactions are eczematous and allergic in nature, although urticarial, bullous......, and vasculitic eruptions may occur. Also, more complex immune reactions may develop around the implants, resulting in pain, inflammation, and loosening. Nickel, cobalt, and chromium are the three most common metals that elicit both cutaneous and extracutaneous allergic reactions from chronic internal exposure......) following the insertion of intravascular stents, dental implants, cardiac pacemakers, or implanted gynecologic devices. Despite repeated attempts by researchers and clinicians to further understand this difficult area of medicine, the association between metal sensitivity and cutaneous allergic reactions...

  12. A system architecture, processor, and communication protocol for secure implants

    NARCIS (Netherlands)

    C. Strydis (Christos); R.M. Seepers (Robert); P. Peris-Lopez (Pedro); D. Siskos (Dimitrios); I. Sourdis (Ioannis)

    2013-01-01

    textabstractSecure and energy-efficient communication between Implantable Medical Devices (IMDs) and authorized external users is attracting increasing attention these days. However, there currently exists no systematic approach to the problem, while solutions from neighboring fields, such as

  13. Cutaneous and systemic hypersensitivity reactions to metallic implants

    DEFF Research Database (Denmark)

    Basko-Plluska, Juliana L; Thyssen, Jacob P; Schalock, Peter C

    2011-01-01

    ) following the insertion of intravascular stents, dental implants, cardiac pacemakers, or implanted gynecologic devices. Despite repeated attempts by researchers and clinicians to further understand this difficult area of medicine, the association between metal sensitivity and cutaneous allergic reactions......Cutaneous reactions to metal implants, orthopedic or otherwise, are well documented in the literature. The first case of a dermatitis reaction over a stainless steel fracture plate was described in 1966. Most skin reactions are eczematous and allergic in nature, although urticarial, bullous......, and vasculitic eruptions may occur. Also, more complex immune reactions may develop around the implants, resulting in pain, inflammation, and loosening. Nickel, cobalt, and chromium are the three most common metals that elicit both cutaneous and extracutaneous allergic reactions from chronic internal exposure...

  14. Prosthodontic maintenance requirements of implant-retained overdentures using the locator attachment system.

    Science.gov (United States)

    Vere, Joe; Hall, Derek; Patel, Raj; Wragg, Phillip

    2012-01-01

    The aim of this study was to investigate the prosthodontic maintenance requirements of patients rehabilitated with maxillary and mandibular implant-retained overdentures using the Locator Attachment System by retrospectively reviewing case records. Fifty patients made 112 unplanned return visits over a 3-year period. The most common reasons for returning were denture adjustments (n = 45), inadequate retention (n = 39), and loosening of the implant abutments (n = 14). Implant-retained overdentures using the Locator Attachment System have comparable prosthodontic maintenance requirements to other attachment systems. Problems associated with these prostheses are usually simple to resolve chairside.

  15. Artery Soft-Tissue Modelling for Stent Implant Training System

    Directory of Open Access Journals (Sweden)

    Giovanni Aloisio

    2004-08-01

    Full Text Available Virtual reality technology can be utilised to provide new systematic training methods for surgical procedures. Our aim is to build a simulator that allows medical students to practice the coronary stent implant procedure and avoids exposing patients to risks. The designed simulation system consists of a virtual environment and a haptic interface, in order to provide both the visualization of the coronary arteries and the tactile and force feedback generated during the interactions of the surgical instruments in the virtual environment. Since the arteries are soft tissues, their shape may change during an operation; for this reason physical modelling of the organs is necessary to render their behaviour under the influence of surgeon's instruments. The idea is to define a model that computes the displacement of the tissue versus time; from the displacement it is possible to calculate the response of the tissue to the surgical tool external stimuli. Information about tools displacements and tissue responses are also used to graphically model the artery wall and virtual surgical instrument deformations generated as a consequence of their coming into contact. In order to obtain a realistic simulation, the Finite Element Method has been used to model the soft tissues of the artery, using linear elasticity to reduce computational time and speed up interaction rates.

  16. Systemic assessment of patients undergoing dental implant surgeries: A trans- and post-operative analysis

    Directory of Open Access Journals (Sweden)

    Sanjay Byakodi

    2017-01-01

    Full Text Available Background: Procedure-related and patient-related factors influence the prognosis of dental implants to a major extent. Hence, we aimed to evaluate and analyze various systemic factors in patients receiving dental implants. Materials and Methods: Fifty-one patients were included in the study, in which a total of 110 dental implants were placed. Complete examination of the subjects was done before and after placement of dental implants. Implant surgery was planned, and osseointegrated dental implants were placed in the subjects. Postoperative evaluation of the dental implant patients was done after 3 weeks. Anxiety levels were determined using State-Trait Anxiety Inventory (STAI questionnaire on the surgery day and after 1 week of surgery. The participant describes how they feel at the moment by responding to twenty items as follows: (1 absolutely not, (2 slightly, (3 somewhat, or (4 very much. All the results were recorded and statistical analyzed by SPSS software. Results: Out of 51, 29 patients were males while 22 were females, with ratio of 1.32:1. Female patients' mean age was 50.18 years while male patients' mean age was 52.71 years, with statistically nonsignificant difference between them. Functional rehabilitation was the main purpose of choosing dental implants in more than 90% of the subjects. Diameter of 3.75 mm was the shortest implants to be placed in the present study, whereas in terms of length, 8.5 mm was the shortest length of dental implant used in the present study. Tooth area in which maximum implants were placed in our study was 36 tooth region. Maximum implants were placed in Type II bone quality (n = 38. Implants installed in the mandible were clamped more efficiently than implants placed in the maxilla (P < 0.001. The difference of average STAI-State subscore before and after the surgery was statistically significant (P < 0.05; significant. Conclusion: Mandibular dental implants show more clamping (torque than maxillary

  17. Chromosomal insertion of the entire Escherichia coli lactose operon, into two strains of Pseudomonas, using a modified mini-Tn5 delivery system

    DEFF Research Database (Denmark)

    Hansen, L. H.; Sørensen, S. J.; Jensen, Lars Bogø

    1997-01-01

    delivery system (de Lorenzo et al., 1990; Herrero et al., 1990), which integrates cloned DNA fragments at random sites on the chromosome of the recipient bacteria in single copies. This has resulted in: (a) the making of two useful low copy-number cloning vectors both with extensive multi-cloning regions...... into the P. fluorescens chromosome giving P. fluorescens the ability to grow on lactose; (d) evidence from Southern blotting that contradicts the assumption that the mini-Tn5 delivery system always creates one-copy inserts. These improvements allow insertion of large DNA fragments encoding highly expressed...

  18. Clinical and radiological results of patients treated with three treatment modalities for overdentures on implants of the ITI (R) Dental Implant System - A randomized controlled clinical trial

    NARCIS (Netherlands)

    Wismeijer, D; van Waas, MAJ; Mulder, J; Vermeeren, JIJF; Kalk, W

    1999-01-01

    In a randomized controlled clinical trial carried out at the Ignatius teaching hospital in Breda, The Netherlands, 110 edentulous patients with severe mandibular bone loss were treated with implants of the ITI(R) Dental Implant System using 3 different treatment strategies: a mandibular overdenture

  19. Clinical and radiological results of patients treated with three treatment modalities for overdentures on implants of the ITI (R) Dental Implant System - A randomized controlled clinical trial

    NARCIS (Netherlands)

    Wismeijer, D; van Waas, MAJ; Mulder, J; Vermeeren, JIJF; Kalk, W

    In a randomized controlled clinical trial carried out at the Ignatius teaching hospital in Breda, The Netherlands, 110 edentulous patients with severe mandibular bone loss were treated with implants of the ITI(R) Dental Implant System using 3 different treatment strategies: a mandibular overdenture

  20. The Thoratec system implanted as a modified total artificial heart: the Bad Oeynhausen technique.

    Science.gov (United States)

    Arusoglu, Latif; Reiss, Nils; Morshuis, Michiel; Schoenbrodt, Michael; Hakim-Meibodi, Kavous; Gummert, Jan

    2010-12-01

    The CardioWest™ total artificial heart (SynCardia Systems, Tuscon, AZ, USA) is the only FDA-approved total artificial heart determined as a bridge to human heart transplantation for patients dying of biventricular heart failure. Implantation provides immediate hemodynamic restoration and clinical stabilization, leading to end-organ recovery and thus eventually allowing cardiac transplantation. Occasionally, implantation of a total artificial heart is not feasible for anatomical reasons. For this patient group, we have developed an alternative technique using the paracorporeal Thoratec biventricular support system (Thoratec, Pleasanton, CA, USA) as a modified total artificial heart. A detailed description of the implantation technique is presented.

  1. Clinical experience with an implanted closed-loop insulin delivery system

    National Research Council Canada - National Science Library

    Eric Renard

    2008-01-01

    ...: The Long-Term Sensor System® project assessed the feasibility of glucose control by the combined implantation of a pump for peritoneal insulin delivery and a central intravenous glucose sensor, connected physically by...

  2. Implant overdenture and Locator system in edentulous patient with severely resorbed mandible - a case report.

    Science.gov (United States)

    Ionescu, Camelia; Gălbinaşu, Bogdan Mihai; Manolea, Horia; Pătraşcu, Ion

    2014-01-01

    Clinical studies have revealed that the main objective of implants in the edentulous jaw is to provide support for fixed prostheses or to stabilize complete dentures. Various attachment systems were developed for universal use in partially and completely edentulous patients such as clasps, cone-shape telescope copings, magnets, bar systems, locators. The aim of this case report is to present the Locator attachment that does not use the splinting of implants. Four implants were placed in the foraminal region and the Locator attachment system was used to connect overdentures to mandibular dental implants. The results proved that the Locator attachment system offers the possibility to obtain a higher retention and an improved stability for overdentures in edentulous patients with a severely resorbed mandible and lack of vertical space between the arches.

  3. Embellecimiento facial con el "sistema matriz de implante mandibular": abordaje endoscópico Facial beauty "mandibular matrix implant system": endoscopic access

    Directory of Open Access Journals (Sweden)

    O. M. Ramírez

    2007-09-01

    del implante, una infección (tratada con irrigación antibiótica y succión, sin necesidad de cambiar el implante y un paciente que precisó remodelación del tamaño del implante. Aunque inicialmente este método se publicó en el año 2000 como técnica mediante abordaje abierto con incisiones intraorales, actualmente recomendamos el método endoscópico, con el cual hemos realizado más de 100 intervenciones, por ser más ventajoso en términos de riesgo de infección. El Sistema Matriz de Implante Mandibular es altamente exitoso por el nivel de satisfacción de los pacientes, la evolución postoperatoria favorable y las expectativas estéticas logradas.One of the most frequent aesthetic problems and of a difficult correction that affects the lower third of the face is the disharmony between the soft tissues and the underlying skeletal support. A loss of volume or a genetically small mandible affects the aesthetics and function of the mouth, chin, and neck. The limitations of the conventional techniques and the limited aesthetic results obtained with those motivated the author to develop a system of implants and a technique of three-dimensional remodeling of the mandible. This system is called Mandibular Matrix Implant System. The Mandibular Matrix Implant System consists of several units, an articulated wraparound geniomandibular implant and two wraparound gonial angle implants, one for each side. A prejowl implant can be integrated in the system as an additional implant as overlay or as a replacement for the chin implant. The implants are made of biocompatible high density porous polyethylene that allows his reshaping and adaptation to the aesthetic needs of every patient. In addition they assemble perfectly to the bony surface of the mandible. It is indicated primarily for the beautification of the facial framework. It can be performed as a separated procedure or in combination with a facial rejuvenation. It is also used in edentulous patients or in those with

  4. Quality Assurance Framework for Mini-Grids

    Energy Technology Data Exchange (ETDEWEB)

    Esterly, Sean; Baring-Gould, Ian; Booth, Samuel

    2017-05-04

    To address the root challenges of providing quality power to remote consumers through financially viable mini-grids, the Global Lighting and Energy Access Partnership (Global LEAP) initiative of the Clean Energy Ministerial and the U.S. Department of Energy teamed with the National Renewable Energy Laboratory (NREL) and Power Africa to develop a Quality Assurance Framework (QAF) for isolated mini-grids. The framework addresses both alternating current (AC) and direct current (DC) mini-grids, and is applicable to renewable, fossil-fuel, and hybrid systems.

  5. Implant Surface Temperature Changes during Er:YAG Laser Irradiation with Different Cooling Systems.

    Science.gov (United States)

    Monzavi, Abbas; Shahabi, Sima; Fekrazad, Reza; Behruzi, Roohollah; Chiniforush, Nasim

    2014-03-01

    Peri-implantitis is one of the most common reasons for implant failure. Decontamination of infected implant surfaces can be achieved effectively by laser irradiation; although the associated thermal rise may cause irreversible bone damage and lead to implant loss. Temperature increments of over 10ºC during laser application may suffice for irreversible bone damage. The purpose of this study was to evaluate the temperature increment of implant surface during Er:YAG laser irradiation with different cooling systems. Three implants were placed in a resected block of sheep mandible and irradiated with Er:YAG laser with 3 different cooling systems namely water and air spray, air spray alone and no water or air spray. Temperature changes of the implant surface were monitored during laser irradiation with a K-type thermocouple at the apical area of the fixture. In all 3 groups, the maximum temperature rise was lower than 10°C. Temperature changes were significantly different with different cooling systems used (Plaser with and without refrigeration. Thus, Er:YAG laser irradiation can be a safe method for treatment of periimplantitis.

  6. A complete data and power telemetry system utilizing BPSK and LSK signaling for biomedical implants.

    Science.gov (United States)

    Sonkusale, Sameer; Luo, Zhenying

    2008-01-01

    In this paper, a prototype of a telemetry system for battery-less biological implant is implemented, which demonstrates both wireless power delivery and duplex wireless data communication. BPSK (Binary Phase Shift Keying) modulation is used for the data transmission from the external controller to the implant and LSK (Load Shift Keying) modulation is used for the reverse data transmission from the implant to the external controller. Power is being delivered wirelessly to the implant through the energy contained in the incoming BPSK data signal. This implant system contains a novel single chip realization of low power BPSK demodulator architecture, which provides considerable power savings compared to prior art. The demodulator occupies 0.1mm(2) area and consumes 5mW power from a 3.3V power supply. A sensitive board level LSK receiver for data transmitted from implant to the external reader has been proposed. External BPSK transmitter consists of a class-E power amplifier that serves the dual purpose of a data transmitter and wireless power delivery. In summary, a very low power bidirectional power and data telemetry system for biological implants based on BPSK and LSK signaling is proposed.

  7. Energy Efficiency and Reliability in Wireless Biomedical Implant Systems

    CERN Document Server

    Abouei, Jamshid; Plataniotis, Konstantinos N; Pasupathy, Subbarayan

    2011-01-01

    The use of wireless implant technology requires correct delivery of the vital physiological signs of the patient along with the energy management in power-constrained devices. Toward these goals, we present an augmentation protocol for the physical layer of the Medical Implant Communications Service (MICS) with focus on the energy efficiency of deployed devices over the MICS frequency band. The present protocol uses the rateless code with the Frequency Shift Keying (FSK) modulation scheme to overcome the reliability and power cost concerns in tiny implantable sensors due to the considerable attenuation of propagated signals across the human body. In addition, the protocol allows a fast start-up time for the transceiver circuitry. The main advantage of using rateless codes is to provide an inherent adaptive duty-cycling for power management, due to the flexibility of the rateless code rate. Analytical results demonstrate that an 80% energy saving is achievable with the proposed protocol when compared to the IE...

  8. [Implant fixation strength and osseointegration following systemic administration of recombinant factor XIII and factor XIII concentrate. Animal experiment with implant fixation strength and osseointegration of porous surface implants].

    Science.gov (United States)

    Kienapfel, H; Wilke, A; Dörner, P; Jürgensen, R; Prinz, H; Hettel, A; Swain, R; Griss, P

    1995-01-01

    30 cylindrical commercially pure titanium fiber porous coated Ti6A14V implants were inserted press-fit into the proximal humeral portion of 30 sheep humeri to determine the systemic effect of recombinant factor XIII and placenta-derived factor XIII concentrate on bone ingrowth and on strength of fixation. For both the recombinant factor XIII and the factor XIII concentrate group the volume fraction of bone ingrowth and the strength of fixation was higher when compared with the control specimens. However the difference was only significant for the factor XIII concentrate group.

  9. Clinical evaluation of a novel dental implant system as single implants under immediate loading conditions - 4-month post-loading results from a multicentre randomised controlled trial.

    Science.gov (United States)

    Esposito, Marco; Trullenque-Eriksson, Anna; Blasone, Rodolfo; Malaguti, Giuliano; Gaffuri, Cristiano; Caneva, Marco; Minciarelli, Armando; Luongo, Giuseppe

    To evaluate the safety and clinical effectiveness of a novel dental implant system (GENESIS Implant System, Keystone Dental, Massachusetts, USA) using another dental implant system by the same manufacturer as a control (PRIMA Implant System, Keystone Dental). A total of 53 patients requiring at least two single crowns had their sites randomised according to a split-mouth design to receive both implant systems at six centres. If implants could be placed with a torque superior to 40 Ncm they were to be loaded immediately with provisional crowns, otherwise after 3 months of submerged healing. Provisional crowns were replaced by definitive crowns 4 months after initial loading, when the follow-up period for the initial part of this study was completed. Outcome measures were crown/implant failures, complications, pink esthetic score (PES), peri-implant marginal bone level changes, plaque score, marginal bleeding, patients and preference of the clinician. In total 53 PRIMA and 53 GENESIS implants were placed. Three patients dropped out but all of the remaining patients were followed up to 4-months post-loading. No PRIMA implant failed whereas four GENESIS implants failed. Only two complications were reported for PRIMA implants. There were no statistically significant differences for crown/implant failures (difference in proportions = 0.080; P (McNemar test) = 0.125) and complications (difference in proportions = -0.04; P (McNemar test) = 0.500) between the implant systems. There were no differences at 4-months post-loading for plaque (difference = -0.54, 95% CI: -3.01 to 1.93; P (Paired t-test) = 0.660), marginal bleeding (difference = -3.8, 95% CI: -7.63 to 0.019; P (Paired t-test) = 0.051), PES (difference = 0.47, 95% CI: -0.56 to 1.50; P (Paired t-test) = 0.365) and marginal bone level changes (difference in mm = -0.04, 95% CI: -0.33 to 0.26; P (Paired t-test) = 0.795). The majority of the patients (46) had no

  10. Characteristics of implant-CAD/CAM abutment connections of two different internal connection systems.

    Science.gov (United States)

    Sumi, T; Braian, M; Shimada, A; Shibata, N; Takeshita, K; Vandeweghe, S; Coelho, P G; Wennerberg, A; Jimbo, R

    2012-05-01

    Titanium or zirconium computer-aided design/computer-aided manufacturing abutments are now widely used for aesthetic implant treatments; however, information regarding microscopic structural differences that may influence the biological and mechanical outcomes of different implant systems is limited. Therefore, the characteristics of different connection systems were investigated. Optical microscopic observation and scanning electron microscopy showed different characteristics of two internal systems, namely the Astra Tech and the Replace Select system, and for different materials. The scanning electron microscopic observation showed for the Astra Tech that the implant-abutment interface seemed to be completely sealed for both titanium and zirconium abutments, both horizontally and sagittally; however, the first implant-abutment contact was below the fixture top, creating a microgap, and fixtures connected with titanium abutments showed significantly larger values (23·56μm±5·44 in width, and 168·78μm±30·39 in depth, P0·70), creating an inverted microgap. Thus, microscopy evaluation of two commonly used internal systems connected to titanium or zirconium abutments showed that the implant-abutment interface was perfectly sealed under no-loading conditions. However, an inverted microgap was seen in both systems, which may result in bacterial accumulation as well as alteration of stress distribution at the implant-abutment interface.

  11. Adjunctive Systemic and Local Antimicrobial Therapy in the Surgical Treatment of Peri-implantitis: A Randomized Controlled Clinical Trial.

    Science.gov (United States)

    Carcuac, O; Derks, J; Charalampakis, G; Abrahamsson, I; Wennström, J; Berglundh, T

    2016-01-01

    The aim of the present randomized controlled clinical trial was to investigate the adjunctive effect of systemic antibiotics and the local use of chlorhexidine for implant surface decontamination in the surgical treatment of peri-implantitis. One hundred patients with severe peri-implantitis were recruited. Surgical therapy was performed with or without adjunctive systemic antibiotics or the local use of chlorhexidine for implant surface decontamination. Treatment outcomes were evaluated at 1 y. A binary logistic regression analysis was used to identify factors influencing the probability of treatment success, that is, probing pocket depth ≤5 mm, absence of bleeding/suppuration on probing, and no additional bone loss. Treatment success was obtained in 45% of all implants but was higher in implants with a nonmodified surface (79%) than those with a modified surface (34%). The local use of chlorhexidine had no overall effect on treatment outcomes. While adjunctive systemic antibiotics had no impact on treatment success at implants with a nonmodified surface, a positive effect on treatment success was observed at implants with a modified surface. The likelihood for treatment success using adjunctive systemic antibiotics in patients with implants with a modified surface, however, was low. As the effect of adjunctive systemic antibiotics depended on implant surface characteristics, recommendations for their use in the surgical treatment of peri-implantitis should be based on careful assessments of the targeted implant (ClinicalTrials.gov NCT01857804).

  12. 种植体与横腭杆支抗对减数正畸患者临床疗效影响的比较%An efficacy comparison between mini-screw implant and transpalatal arch on dentofacial morphology in extraction cases

    Institute of Scientific and Technical Information of China (English)

    刘月华; 刘晶; 李强; 丁王辉

    2009-01-01

    lusions As orthodontic anchorage, mini-screw implants were different from TPA. Mini-acrew implant could not only retract the upper incisors but also slightly intrude upper incisors and upper molars.%74±2.66)mm,上唇突点后移(4.61±2.00)mm;矫治后横腭杆支抗组上切牙腭向移动(4.59±1.78)mm,伸长(0.93±1.77)mm,上颌第一磨牙近中移动(1.65±1.87)mm,伸长(0.52±1.59)mm,上唇突点后移(3.07±2.02)mm;两组差异均有统计学意义(P<0.05).结论 种植体支抗的作用明显强于横腭杆支抗,种植体不仅能大幅度内收前牙,改善侧貌,有效压低上切牙以利于矫正深覆胎、露龈笑,还可压低上颌磨牙.

  13. Processing of microCT implant-bone systems images using Fuzzy Mathematical Morphology

    Science.gov (United States)

    Bouchet, A.; Colabella, L.; Omar, S.; Ballarre, J.; Pastore, J.

    2016-04-01

    The relationship between a metallic implant and the existing bone in a surgical permanent prosthesis is of great importance since the fixation and osseointegration of the system leads to the failure or success of the surgery. Micro Computed Tomography is a technique that helps to visualize the structure of the bone. In this study, the microCT is used to analyze implant-bone systems images. However, one of the problems presented in the reconstruction of these images is the effect of the iron based implants, with a halo or fluorescence scattering distorting the micro CT image and leading to bad 3D reconstructions. In this work we introduce an automatic method for eliminate the effect of AISI 316L iron materials in the implant-bone system based on the application of Compensatory Fuzzy Mathematical Morphology for future investigate about the structural and mechanical properties of bone and cancellous materials.

  14. Numerical estimation of heat distribution from the implantable battery system of an undulation pump LVAD.

    Science.gov (United States)

    Okamoto, Eiji; Makino, Tsutomu; Nakamura, Masatoshi; Tanaka, Shuji; Chinzei, Tsuneo; Abe, Yusuke; Isoyama, Takashi; Saito, Itsuro; Mochizuki, Shu-ichi; Imachi, Kou; Inoue, Yusuke; Mitamura, Yoshinori

    2006-01-01

    We have been developing an implantable battery system using three series-connected lithium ion batteries having an energy capacity of 1,800 mAh to drive an undulation pump left ventricular assist device. However, the lithium ion battery undergoes an exothermic reaction during the discharge phase, and the temperature rise of the lithium ion battery is a critical issue for implantation usage. Heat generation in the lithium ion battery depends on the intensity of the discharge current, and we obtained a relationship between the heat flow from the lithium ion battery q(c)(I) and the intensity of the discharge current I as q(c)(I) = 0.63 x I (W) in in vitro experiments. The temperature distribution of the implantable battery system was estimated by means of three-dimentional finite-element method (FEM) heat transfer analysis using the heat flow function q(c)(I), and we also measured the temperature rise of the implantable battery system in in vitro experiments to conduct verification of the estimation. The maximum temperatures of the lithium ion battery and the implantable battery case were measured as 52.2 degrees C and 41.1 degrees C, respectively. The estimated result of temperature distribution of the implantable battery system agreed well with the measured results using thermography. In conclusion, FEM heat transfer analysis is promising as a tool to estimate the temperature of the implantable lithium ion battery system under any pump current without the need for animal experiments, and it is a convenient tool for optimization of heat transfer characteristics of the implantable battery system.

  15. A system architecture, processor, and communication protocol for secure implants

    NARCIS (Netherlands)

    C. Strydis (Christos); R.M. Seepers (Robert); P. Peris-Lopez (Pedro); D. Siskos (Dimitrios); I. Sourdis (Ioannis)

    2013-01-01

    textabstractSecure and energy-efficient communication between Implantable Medical Devices (IMDs) and authorized external users is attracting increasing attention these days. However, there currently exists no systematic approach to the problem, while solutions from neighboring fields, such as wirele

  16. 120-kV ion-implantation system

    Energy Technology Data Exchange (ETDEWEB)

    Bhatia, M.S.; Bhattacharya, P.K.; Gaonkar, S.; Kansara, M.J.; Sarma, N.; Wagh, A.G.

    1980-01-01

    A compact and versatile heavy ion accelerator has been constructed for the uniform implantation of wafers with beams of microamperes and acceleration voltages of up to 120 keV. The mass analysis of the ion beam is carried out within the high voltage terminal at an energy of 10 keV after beam formation and focussing by an Extractor-cum-Einzel lens. The electromagnet utilized for this was of 14/sup 0/ bending angle. Acceleration is provided by a modified insulated core transformer of five sections operating on three phase power input. Provision is made for the implantation of either single targets and for the batch implantation of up to 36 wafers at a time. The ion source is a Nielsen type in which evaporation and ionization are achieved by the impact of thermionic electrons from a hot filament. It is capable of delivering currents in the microampere range for most of the elements and accepts liquid, solid and gaseous charges. While the facility enables implants of a wide range of doses, species and energies, it is mainly used for boron and phosphorous doping in semiconductors. Electrostatic scanning in two dimensions ensures maximum uniformity. All controls are operated at ground potential and are easily accessible.

  17. Simple, quick, and efficient implant placement jig

    Directory of Open Access Journals (Sweden)

    Nikhil Narayan Pai

    2015-01-01

    Full Text Available Implants have become an inherent part of everyday orthodontic practice, but unlike prosthodontic implants, their placement and insertion into narrow interradicular spaces for orthodontic purposes remain a tricky and challenging part to most clinicians. An innovative and clinically useful method has been described here for safe and easy insertion of mini-implants.

  18. The KineSpring® Knee Implant System: an implantable joint-unloading prosthesis for treatment of medial knee osteoarthritis

    Directory of Open Access Journals (Sweden)

    Clifford AG

    2013-05-01

    Full Text Available Anton G Clifford,1 Stefan M Gabriel,1 Mary O’Connell,1 David Lowe,1 Larry E Miller,2,3 Jon E Block31Moximed, Inc, Hayward, CA, USA; 2Miller Scientific Consulting, Inc, Arden, NC, USA; 3The Jon Block Group, San Francisco, CA, USAAbstract: Symptomatic medial compartment knee osteoarthritis (OA is the leading cause of musculoskeletal pain and disability in adults. Therapies intended to unload the medial knee compartment have yielded unsatisfactory results due to low patient compliance with conservative treatments and high complication rates with surgical options. There is no widely available joint-unloading treatment for medial knee OA that offers clinically important symptom alleviation, low complication risk, and high patient acceptance. The KineSpring® Knee Implant System (Moximed, Inc, Hayward, CA, USA is a first-of-its-kind, implantable, extra-articular, extra-capsular prosthesis intended to alleviate knee OA-related symptoms by reducing medial knee compartment loading while overcoming the limitations of traditional joint-unloading therapies. Preclinical and clinical studies have demonstrated excellent prosthesis durability, substantial reductions in medial compartment and total joint loads, and clinically important improvements in OA-related pain and function. The purpose of this report is to describe the KineSpring System, including implant characteristics, principles of operation, indications for use, patient selection criteria, surgical technique, postoperative care, preclinical testing, and clinical experience. The KineSpring System has potential to bridge the gap between ineffective conservative treatments and irreversible surgical interventions for medial compartment knee OA.Keywords: KineSpring, knee, medial, osteoarthritis, prosthesis

  19. Monte Carlo studies of positron implantation in elemental metallic and multilayer systems

    Energy Technology Data Exchange (ETDEWEB)

    Ghosh, V.J.; Welch, D.O.; Lynn, K.G.

    1992-01-01

    We have used a Monte Carlo computer code developed at Brookhaven [sup 1,2] to study the implantation profiles of 1-10 keV positrons incident on a wide range of semi-infinite metals and multilayer systems. Our Monte Carlo program accounts for elastic scattering as well as inelastic scattering from core and valence electrons, and includes the excitation of plasmons. The implantation profiles of positrons in many metals as well as Pd/Al, and Al/Co/Si multilayers are presented. Scaling relations and closed-form expressions representing he implantation profiles are also discussed.

  20. Monte Carlo studies of positron implantation in elemental metallic and multilayer systems

    Energy Technology Data Exchange (ETDEWEB)

    Ghosh, V.J.; Welch, D.O.; Lynn, K.G.

    1992-12-01

    We have used a Monte Carlo computer code developed at Brookhaven {sup 1,2} to study the implantation profiles of 1-10 keV positrons incident on a wide range of semi-infinite metals and multilayer systems. Our Monte Carlo program accounts for elastic scattering as well as inelastic scattering from core and valence electrons, and includes the excitation of plasmons. The implantation profiles of positrons in many metals as well as Pd/Al, and Al/Co/Si multilayers are presented. Scaling relations and closed-form expressions representing he implantation profiles are also discussed.

  1. Mini-guide til DGNB

    DEFF Research Database (Denmark)

    Larsen, Tine Steen

    Guiden giver et kort indblik i formålet med de enkelte kriterier i en DGNB- bæredygtighedsvurdering, samt i hvordan der kan måles på kriterierne. Mini-guiden tager afsæt i systemet for certificering af Nybyggede kontor-og erhvervsbyggerier, som er det første og grundlæggende system i DGNB, som al...

  2. Fiscal 1999 achievement report on regional consortium research and development project. Regional consortium research and development in its 1st year (Research for development of high-performance mini-scale manufacturing system for very small precision machine parts); 1999 nendo kogata seimitsu kiki buhin'yo kokino mini seisan system no kaihatsu kenkyu seika hokokusho. 1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    Research and development is conducted of a flexible manufacturing system which uses mini-scale production cells capable of dealing with environmental and energy conservation problems, to be operated for the manufacture of small quantities of multiple kinds of goods. The concept of total system is that work pieces fall within the dimensions 15mm diameter times 50mm in length and that 14 kinds of cells be built out of 36 kinds of units. A control system chart is prepared, in which the units, the cells, and the whole are to be allotted to their respective control units according to their functions. In the development and designing of units to constitute mini-scale production cells and functional elements for them, problems to arise from miniaturization are considered, miniaturized tool rests are designed, built-in motor type main shafts are designed, and it is now expected that cylinder grinding cells will roughly satisfy the target dimensions and weight. In the development and fabrication of mini-scale production cells and units, cylinder grinding stone spindle units, traverse table units, grinding cell control devices, etc., are fabricated. (NEDO)

  3. Implantable power generation system utilizing muscle contractions excited by electrical stimulation.

    Science.gov (United States)

    Sahara, Genta; Hijikata, Wataru; Tomioka, Kota; Shinshi, Tadahiko

    2016-06-01

    An implantable power generation system driven by muscle contractions for supplying power to active implantable medical devices, such as pacemakers and neurostimulators, is proposed. In this system, a muscle is intentionally contracted by an electrical stimulation in accordance with the demands of the active implantable medical device for electrical power. The proposed system, which comprises a small electromagnetic induction generator, electrodes with an electrical circuit for stimulation and a transmission device to convert the linear motion of the muscle contractions into rotational motion for the magneto rotor, generates electrical energy. In an ex vivo demonstration using the gastrocnemius muscle of a toad, which was 28 mm in length and weighed 1.3 g, the electrical energy generated by the prototype exceeded the energy consumed for electrical stimulation, with the net power being 111 µW. It was demonstrated that the proposed implantable power generation system has the potential to replace implantable batteries for active implantable medical devices. © IMechE 2016.

  4. Infrared Thermographic Assessment of Cooling Effectiveness in Selected Dental Implant Systems

    Directory of Open Access Journals (Sweden)

    Karol Kirstein

    2016-01-01

    Full Text Available The excessive temperature fluctuations during dental implant site preparation may affect the process of bone-implant osseointegration. In the presented studies, we aimed to assess the quality of cooling during the use of 3 different dental implant systems (BEGO®, NEO BIOTECH®, and BIOMET 3i®. The swine rib was chosen as a study model. The preparation of dental implant site was performed with the use of 3 different speeds of rotation (800, 1,200, and 1,500 rpm and three types of cooling: with saline solution at room temperature, with saline solution cooled down to 3°C, and without cooling. A statistically significant difference in temperature fluctuations was observed between BEGO and NEO BIOTECH dental systems when cooling with saline solution at 3°C was used (22.3°C versus 21.8°C. In case of all three evaluated dental implant systems, the highest temperature fluctuations occurred when pilot drills were used for implant site preparation. The critical temperature, defined in the available literature, was exceeded only in case of pilot drills (of all 3 systems used at rotation speed of 1,500 rpm without cooling.

  5. [A case of percutaneous coronary intervention after transfemoral implantation of a medtronic CoreValve System].

    Science.gov (United States)

    Corcione, Nicola; Ferraro, Paolo; Polimeno, Michele; Messina, Stefano; de Rosa, Vincenzo; Giordano, Arturo

    2011-12-01

    The association between aortic valve disease and coronary atherosclerosis is common. In the recent era of transcatheter aortic valve implantation there is little experience with coronary artery intervention after valve implantation. We report a case of a 80-year-old male who underwent successful coronary artery intervention few months after a Medtronic CoreValve System percutaneous implantation for severe aortic valve stenosis. Verification of the position of the used wires (crossing from inside the self expanding frame) is of utmost importance before proceeding to coronary intervention. In this case, crossing the aortic valve, coronary angiography and percutaneous coronary intervention were successfully performed. In conclusion, percutaneous coronary intervention in patients with previous Medtronic CoreValve System implantation is feasible and safe.

  6. Complication incidence of two implant systems up to six years: a comparison between internal and external connection implants.

    Science.gov (United States)

    Chae, Sung-Wook; Kim, Young-Sung; Lee, Yong-Moo; Kim, Won-Kyung; Lee, Young-Kyoo; Kim, Su-Hwan

    2015-02-01

    This study was conducted to compare the cumulative survival rates (CSRs) and the incidence of postloading complications (PLCs) between a bone-level internal connection system (ICS-BL) and an external connection system (ECS). The medical records of patients treated with either a ICS-BL or ECS between 2007 and 2010 at Asan Medical Center were reviewed. PLCs were divided into two categories: biological and technical. Biological complications included >4 mm of probing pocket depth, thread exposure in radiographs, and soft tissue complications, whereas technical complications included chipping of the veneering material, fracture of the implant, fracture of the crown, loosening or fracture of the abutment or screw, loss of retention, and loss of access hole filling material. CSRs were determined by a life-table analysis and compared using the log-rank chi-square test. The incidence of PLC was compared with the Pearson chi-squared test. A total of 2,651 implants in 1,074 patients (1,167 ICS-BLs in 551 patients and 1,484 ECSs in 523 patients) were analyzed. The average observation periods were 3.4 years for the ICS-BLs and 3.1 years for the ECSs. The six-year CSR of all implants was 96.1% (94.9% for the ICS-BLs and 97.1% for the ECSs, P=0.619). Soft tissue complications were more frequent with the ECSs (P=0.005) and loosening or fracture of the abutment or screw occurred more frequently with the ICS-BLs (P<0.001). Within the limitations of this study, the ICS-BL was more prone to technical complications while the ECS was more vulnerable to biological complications.

  7. Long-term implant prognosis in patients with and without a history of chronic periodontitis: a 10-year prospective cohort study of the ITI Dental Implant System.

    Science.gov (United States)

    Karoussis, Ioannis K; Salvi, Giovanni E; Heitz-Mayfield, Lisa J A; Brägger, Urs; Hämmerle, Christoph H F; Lang, Niklaus P

    2003-06-01

    The aim of this 10-year study was to compare the failure, success and complication rates between patients having lost their teeth due to periodontitis or other reasons. Fifty-three patients who received 112 hollow screw implants (HS) of the ITI Dental Implant System were divided into two groups: group A - eight patients with 21 implants having lost their teeth due to chronic periodontitis; group B - forty five patients with 91 implants without a history of periodontitis. One and 10 years after surgical placement, clinical and radiographic parameters were assessed. The incidences of peri-implantitis were noticed over the 10 years of regular supportive periodontal therapy. Success criteria at 10 years were set at: pocket probing depth (PPD) periodontitis (group A) was 90.5%, while for the group with no past history of periodontitis (group B) it was 96.5%. Group A had a significantly higher incidence of peri-implantitis than group B (28.6% vs. 5.8%). With the success criteria set, 52.4% in group A and 79.1% of the implants in group B were successful. With a threshold set at PPD periodontitis demonstrated lower survival rates and more biological complications than patients with implants replacing teeth lost due to reasons other than periodontitis during a 10-year maintenance period. Furthermore, setting of thresholds for success criteria is crucial to the reporting of success rates.

  8. Design analysis of an implant and antenna system by using Taguchi method

    Science.gov (United States)

    Celik, Nevin; Turgut, Emre; Bayazit, Yilmaz

    2017-08-01

    In present study, to investigate the thermal effects of the rechargeable neuromodulation implants (an implant and antenna together) in the body, a numerical analysis is performed by using commercial software ANSYS. Since it is well established that both the antenna and the implant generate heat, both of these heat sources may increase the tissue temperature in the subcutaneous zone and may also increase the temperature in the deeper tissue. Therefore, the sizes and heat generation amounts of the implant-antenna system gain great importance and a parametric evaluation that shows the effects of the design parameters on the temperature becomes necessary. For this aim, an optimization study is performed. The runs of the numerical simulations are determined by well-known design analysis method, namely Taguchi and the parametric evaluation of the study is carried out by Analysis of Variance (ANOVA) method. The design parameters considered are; (i) heat generated by the antenna q a (50, 52 and 54 W/m2), (ii) heat generated by the implant q i (30 and 35 W/m2), (iii) thickness of the implant t i (9, 11, and 13 mm) and finally (iv) the radius of the antenna R a (31, 35, 39 mm). The results showed that higher antenna radii result in higher temperatures in the tissue, whilst the least effective design parameter on the temperature is the heat generation of the implant.

  9. Dental Implant Placement using C-arm CT Real Time Imaging System: A Case Report.

    Science.gov (United States)

    Rajkumar, B; Boruah, Lalit C; Thind, Amandeep; Jain, Gaurav; Gupta, Shilpi

    2014-12-01

    C-arm computed tomography (CT) is a new and innovative imaging technique. In combination with two-dimensional fluoroscopic or radiographic imaging, information provided by three-dimensional C-arm real time imaging can be valuable for therapy planning, guidance and outcome assessment in dental implant placement. This paper reports a case of two dental implant placement using Artis zee C-arm CT system first time in field of implantology.

  10. MiniBooNE

    Energy Technology Data Exchange (ETDEWEB)

    Mahn, Kendall Brianna Mcconnel; /Columbia U.

    2007-03-01

    MiniBooNE is a short baseline neutrino experiment designed to confirm or refute the LSND observed excess of electron anti neutrinos in a muon anti neutrino beam. The experimental setup, data samples, and oscillation fit method are discussed. Although the result was not public at the time of the talk, MiniBooNE has since published results, which are discussed briefly as well.

  11. Orthodontic Anchorage Implants: State-of-the-art

    DEFF Research Database (Denmark)

    Melsen, Birte

    2007-01-01

    The limits of an orthodontic treatment are often set by the lack of suitable anchorage. The mini-implant is used where conventional anchorage cannot be applied and not as a replacement for conventional anchorage. In patients with lack of teeth and reduced periodontium, skeletal anchorage allows...... will improve the reconstruction possibilities. The mini-implant has widened the orthodontic possibilities....

  12. The MiniCLEAN Experiment

    Science.gov (United States)

    Wang, Jui-Jen (Ryan); Gold, Michael; Miniclean Collaboration

    2017-01-01

    The MiniCLEAN (Cryogenic Low-Energy Astrophysics with Noble liquid) dark matter experiment will exploit a single-phase liquid argon detector instrumented with 92 photomultiplier tubes placed in the cryogen with 4- π coverage of a 500 kg (150 kg) target (fiducial) mass. The detector design strategy emphasizes scalability to target masses of order 10 tons or more. It is designed also for a liquid neon target that allows for an independent verification of signal and background and a test of the expected dependence of the WIMP-nucleus interaction rate. For MiniCLEAN, PMT stability and calibration are essential. The Light-Emitting Diode (LED) based light injection system provide single photon for the calibration which can be performed in near real-time, providing a continuous monitor on the condition of the detector. This talk will summarize the status of detector and upcoming commissioning at SNOLAB in Sudbury, Canada.

  13. Replace种植系统在即刻种植中的临床应用研究%Clinical application of Replace implant system in the immediate implantation

    Institute of Scientific and Technical Information of China (English)

    张庆元; 张兆强; 张清彬; 刘佳钰

    2012-01-01

    目的:评价Replace种植系统应用于即刻种植的临床效果.方法:收集2006年2月~2008年2月期间具有即刻种植适应症的28例患者,行Replace种植系统植入术,术后3~6个月根据临床和影像学结果行二期手术及上部结构修复,随访观察18~36个月(平均15个月).结果:共植入47枚种植体,其中45枚获得成功,在随访期内无明显并发症,种植体负重后第1年牙槽骨吸收水平<1 mm.1例糖尿病患者2枚种植体于二期修复后7周脱落,成功率为95.74%(45/47).种植体周围龈炎4枚,烤瓷冠崩瓷2枚.结论:Replace即刻种植可缩短患者缺牙时间,减缓牙槽嵴吸收,患者满意度较高,但必须严格掌握适应症.%Objective: To evaluate the clinical effect of Replace implant system in application of the immediate implantation. Method:The Replace implant system was implanted in 28 patients who adapted to immediate implantation during February in 2006 to February in 2008. The dental implant rehabilitation was administered 3-6 months after the implant surgery in accordance lo the clinical and radiographic parameters. The clinical effect was followed up over 18-36 months (average IS months). Result:45 of all the 47 implants were successive and without obvious complication in the follow-up period t the absorption level of alveolar bone was less than I mm in the first year after rehabilitation. 2 implants embedded in the patient with diabetes dropped 7 weeks after the rehabilitation. The success rate was 95.74 % (45 / 47). There were 4 implants involved with peri-implant mucositis and 2 metal-porcelain full crowns yielded ceramic chipping. Conclusion: Immediate implantation with the Replace system could shorten the anodonlia time and slow down the absorption pace of alveolar bone. Patients were highly satisfied with the immediate implantation, However.the indication must be controlled strictly.

  14. A bone quality-based implant system: a preliminary report of stage I & stage II.

    Science.gov (United States)

    Misch, C E; Hoar, J; Beck, G; Hazen, R; Misch, C M

    1998-01-01

    A system is introduced in which dental implants are specifically designed for containment within four different categories of bone densities. The sizes and the textured surfaces that accompany the gradations of lengths and diameters are standardized for each bone type. A modified thread design focuses on compression of bone rather than on shear, and the geometry of the entire implant body reflects features that are concurrent with a "platform effect." Having been tested by means of finite element analysis and initial animal studies, the results are provided herein for the placement of 364 consecutive implants in five clinical centers on human patients, with surgical survival results of 98.9 percent overall. The initial clinical report of these implants indicates that all bone densities may have similar initial survival rates.

  15. Security Risks, Low-tech User Interfaces, and Implantable Medical Devices: A Case Study with Insulin Pump Infusion Systems

    Energy Technology Data Exchange (ETDEWEB)

    Paul, Nathanael R [ORNL; Kohno, Tadayoshi [University of Washington, Seattle

    2012-01-01

    Portable implantable medical device systems are playing a larger role in modern health care. Increasing attention is now being given to the wireless control interface of these systems. Our position is that wireless security in portable implantable medical device systems is just a part of the overall system security, and increased attention is needed to address low-tech security issues.

  16. A novel amorphous calcium phosphate drug-eluting stent:its biocompatibility after implantation into mini-swine coronary artery%新型纳米材料无定形磷酸钙药物支架置入小型猪冠状动脉后的生物相容性

    Institute of Scientific and Technical Information of China (English)

    谭峥; 李莉; 马燚

    2016-01-01

    BACKGROUND:As previously reported, poly-L-lactic acid stents have been mostly used as coronary artery stents, but this stent has a lack of early support force and produces some acidic products that wil induce local vascular inflammatory reactions. OBJECTIVE:To explore the biocompatibility of a novel amorphous calcium phosphate drug-eluting stent, after implantation into mini-swine coronary artery. METHODS:Twenty mini-swine were randomly equivalently divided into observation group and control group. The right femoral arteries of animals were separated layer by layer and the new type of biodegradable stent and poly-L-lactic acid stent were implanted, respectively. RESULTS AND CONCLUSION:The vessel lumes in the two groups were smooth and unobstructed showed by coronary artery angiography immediately after implantation. At 4 weeks after implantation, the coronary angiography showed the patency of vessel lumens with no stent thrombosis and stenosis in both two groups. The C-reactive protein levels in the two groups had no significant differences before and 4 weeks after stent implantation. At 4 weeks after implantation, the number of lymphocytes and inflammatory score in the observation group were significantly higher than those in the control group, but the neointimal area and percentage of stenosis area had no significant difference between the two groups. These results indicate that the novel amorphous calcium phosphate drug-eluting stent after implantation into mini-swine coronary artery has good biocompatibility.%背景:以往冠状动脉植入支架大多为聚左旋乳酸,但存在早期支撑力不足的问题,且会产生一定的酸性产物,导致血管局部出现炎性反应。  目的:探讨新型纳米材料无定形磷酸钙药物支架置入小型猪冠状动脉后的生物相容性。  方法:20只小型猪随机等分为观察组和对照组,对动物右侧股动脉予以逐层分离,分别置入新型生物全降解支架和

  17. 微型种植体支抗辅助牵引成骨重建上颌骨部分缺损的效果评估%Mini-screw implant anchorage-assisted distraction osteogenesis for reconstruction of partial maxillary defect

    Institute of Scientific and Technical Information of China (English)

    冯贻苗; 沈国芳; 房兵; 毛丽霞; 娄新田

    2009-01-01

    PURPOSE:To evaluate the usefulness of self-made distraction osteogenesis instrument by orthodontic technique and mini-screw implant anchorage-assisted distraction osteogenesis(DO) to reconstruct partial maxillary defects. METHODS: Eight patients suffering from partial maxillary defects were selected. Their ages ranged from 19 to 43 years and the average age was 33.2 years. There were 5 males. After a special instrument was fabricated, elastic force trifocal distraction was performed by mini-implant borne aneborage. Three months later the implants were implanted in the two distracted region and the prosthetic restorations were finished finally. RESULTS: In the areas of distraction osteogenesis, ossifications were fine and alveolar bones were completed. The partial maxillary defects were repaired with the implant technique and the prosthodontie technique, and favourable occlusion was obtained. CONCLUSION: Combined orthodontic and DO techniques can reconstruct partial maxillary defect successfully and restore the complicated anatomical contour of the maxilla, especially the dental-alveolar bone.%目的:评价正畸技术自制牵引成骨装置及微型种植体支抗辅助弹力牵引重建上颌骨部分缺损的疗效.方法:选择5例上颌骨部分缺损病例,均为男性,年龄19~43岁,平均33.2岁.制作特殊的牵引装置.采用微型种植体支抗辅助支持的弹力牵引方式,进行三焦点式牵引成骨.3个月后,在两侧牵引区植入种植体,进行牙列修复.结果:骨缺损区牵引成骨后成骨良好,形成完整的牙槽嵴,可应用种植和托牙技术进行牙列修复,恢复良好的咬合关系.结论:对上颌骨部分骨缺损病例,可应用正畸技术和牵引成骨技术联合治疗,以恢复颌骨复杂的解剖结构,尤其是牙槽嵴,为牙列修复提供必备的条件.

  18. Walking after incomplete spinal cord injury using an implanted FES system: a case report.

    Science.gov (United States)

    Hardin, Elizabeth; Kobetic, Rudi; Murray, Lori; Corado-Ahmed, Michelle; Pinault, Gilles; Sakai, Jonathan; Bailey, Stephanie Nogan; Ho, Chester; Triolo, Ronald J

    2007-01-01

    Implanted functional electrical stimulation (FES) systems for walking are experimentally available to individuals with incomplete spinal cord injury (SCI); however, data on short-term therapeutic and functional outcomes are limited. The goal of this study was to quantify therapeutic and functional effects of an implanted FES system for walking after incomplete cervical SCI. After robotic-assisted treadmill training and overground gait training maximized his voluntary function, an individual with incomplete SCI (American Spinal Injury Association grade C, cervical level 6-7) who could stand volitionally but not step was surgically implanted with an 8-channel receiver stimulator and intramuscular electrodes. Electrodes were implanted bilaterally, recruiting iliopsoas, vastus intermedius and lateralis, tensor fasciae latae, tibialis anterior, and peroneus longus muscles. Twelve weeks of training followed limited activity post-surgery. Customized stimulation patterns addressed gait deficits via an external control unit. The system was well-tolerated and reliable. After the 12-week training, maximal walking distance increased (from 14 m to 309 m), maximal walking speed was 10 times greater (from 0.02 m/s to 0.20 m/s), and physiological cost index was 5 times less (from 44.4 beats/m to 8.6 beats/m). Voluntary locomotor function was unchanged. The implanted FES system was well-tolerated, reliable, and supplemented function, allowing the participant limited community ambulation. Physiological effort decreased and maximal walking distance increased dramatically over 12 weeks.

  19. The validity and responsiveness of the Chinese version of the mini-Balance Evaluation Systems Test%简易平衡评定系统测试量表的效度与敏感度研究

    Institute of Scientific and Technical Information of China (English)

    陈长香; 王云龙; 马素慧; 窦娜; 李丹

    2015-01-01

    目的 探讨简易平衡评定系统测试(mini-BESTest)量表的效度及敏感度.方法 由2名专业人员对符合入选标准的208例脑卒中患者进行mini-BESTest及Berg平衡量表(BBS)测试,采用Pearson相关分析、配对t检验和描述性统计方法对数据进行处理.结果 mini-BESTest每项条目与其所在维度相关系数范围为0.782 ~0.934(P <0.05),mini-BESTest与BBS总分及各维度得分的相关系数范围为0.682~0.873(P<0.05);康复训练2周后,mini-BESTest总分、4个维度得分和BBS总分均显著提高(P<0.05);miniBESTest总分无天花板效应和地板效应,预订姿势调整、方位觉维度有轻微天花板效应,姿势反应维度有轻微地板效应,但优于BBS.结论 mini-BESTest量表具有较好的内容效度、效标效度及敏感度,可在脑卒中患者的康复评价中应用、推广.%Objective To evaluate the validity and responsiveness of the Chinese version of the miniBalance Evaluation Systems Test(mini-BESTest).Methods A total of 208 stroke patients were evaluated by 2 professionals using both mini-BESTest and Berg balance scale (BBS).All data were analyzed using Pearson correlation,t-test and descriptive statistical analysis.Results Significant correlation was observed between each entry of the mini-BESTest and its domain,with correlation coefficients ranging from 0.78 to 0.93 (P < 0.05).The scores of whole assessment and the three related domains were significantly correlated between mini-BESTest and BBS results,the correlation coefficients ranging from 0.68 to 0.87 (P < 0.05).After 2 weeks of treatment,there was significant improvement in each domain and in the total assessment score (P < 0.05).No floor or ceiling effects were observed in the total mini-BESTest scores,but there was a slight ceiling effect in the anticipatory and sensory orientation domains,and a slight floor effect in the reactive postural control domain.Conclusion The mini-BESTest has good validity and

  20. Miniature Coplanar Implantable Antenna on Thin and Flexible Platform for Fully Wireless Intracranial Pressure Monitoring System

    Directory of Open Access Journals (Sweden)

    M. Waqas A. Khan

    2017-01-01

    Full Text Available Minimally invasive approach to intracranial pressure monitoring is desired for long-term diagnostics. The monitored pressure is transmitted outside the skull through an implant antenna. We present a new miniature (6 mm × 5 mm coplanar implant antenna and its integration on a sensor platform to establish a far-field data link for the sensor readout at distances of 0.5 to 1 meter. The implant antenna was developed using full-wave electromagnetic simulator and measured in a liquid phantom mimicking the dielectric properties of the human head. It achieved impedance reflection coefficient better than −10 dB from 2.38 GHz to 2.54 GHz which covers the targeted industrial, scientific, and medical band. Experiments resulted in an acceptable peak gain of approximately −23 dBi. The implant antenna was submerged in the liquid phantom and interfaced to a 0.5 mW voltage controlled oscillator. To verify the implant antenna performance as a part of the ICP monitoring system, we recorded the radiated signal strength using a spectrum analyzer. Using a half-wavelength dipole as the receiving antenna, we captured approximately −58.7 dBm signal at a distance of 1 m from the implant antenna which is well above for the reader with sensitivity of −80 dBm.

  1. The Safety of MR Conditional Cochlear Implant at 1.5 Tesla Magnetic Resonance Imaging System.

    Science.gov (United States)

    Takahashi, Daisuke; Ogura, Akio; Hayashi, Norio; Seino, Shinya; Kawai, Ryosuke; Matsuda, Tsuyoshi; Doi, Tsukasa; Tsuchihashi, Toshio

    2016-08-01

    In magnetic resonance imaging (MRI) examination of the patients with the cochlear implant, only limited data have a mention for safety information in the instruction manual supplied by the manufacturers. Therefore, imaging operators require more detailed safety information for implant device. We conducted detailed examination about displacement force, torque, and demagnetizing of the cochlear implant magnet based on American Society for Testing and Materials (ASTM) standard using the PULSAR and CONCERTO (MED-EL) with 1.5 tesla MRI system. As a result, the displacement force and the torque of the implant magnet were less than the numerical values descried in the manual. Therefore, these have almost no effect on the body under the condition described in a manual. In addition, the demagnetizing factor of the cochlear implant magnet occurred by a change magnetic field. The demagnetization depended on the direction of a line of magnetic force of the static magnetic field and the implant magnet. In conclusion, the operator must warn the position of the patients on inducing in the magnet room.

  2. A morphological analysis on the osteocytic lacunar canalicular system in bone surrounding dental implants.

    Science.gov (United States)

    Haga, Maiko; Nozawa-Inoue, Kayoko; Li, Minqi; Oda, Kimimitsu; Yoshie, Sumio; Amizuka, Norio; Maeda, Takeyasu

    2011-06-01

    Osseointegration is the most preferable interface of dental implants and newly formed bone. However, the cavity preparation for dental implants often gives rise to empty lacunae or pyknotic osteocytes in bone surrounding the dental implant. This study aimed to examine the chronological alternation of osteocytes in the bone surrounding the titanium implants using a rat model. The distribution of the osteocytic lacunar canalicular system (OLCS) in bone around the titanium implants was examined by silver impregnation according to Bodian's staining. We also performed double staining for alkaline phosphatase (ALP) and tartrate-resistant acid phosphatase (TRAP), as well as immunohistochemistry for fibroblast growth factor (FGF) 23--a regulator for the serum concentration of phosphorus--and sclerostin, which has been shown to inhibit osteoblastic activities. Newly formed bone and the injured bone at the early stage exhibited an irregularly distributed OLCS and a few osteocytes positive for sclerostin or FGF23, therefore indicating immature bone. Osteocytes in the surrounding bone from Day 20 to Month 2 came to reveal an intense immunoreactivity for sclerostin. Later on, the physiological bone remodeling gradually replaced such immature bone into a compact profile bearing a regularly arranged OLCS. As the bone was remodeled, FGF23 immunoreactivity became more intense, but sclerostin became less so in the well-arranged OLCS. In summary, it seems likely that OLCS in the bone surrounding the dental implants is damaged by cavity formation, but later gradually recovers as bone remodeling takes place, ultimately inducing mature bone. Copyright © 2011 Wiley-Liss, Inc.

  3. Approaches and Challenges of Engineering Implantable Microelectromechanical Systems (MEMS Drug Delivery Systems for in Vitro and in Vivo Applications

    Directory of Open Access Journals (Sweden)

    Ken-Tye Yong

    2012-11-01

    Full Text Available Despite the advancements made in drug delivery systems over the years, many challenges remain in drug delivery systems for treating chronic diseases at the personalized medicine level. The current urgent need is to develop novel strategies for targeted therapy of chronic diseases. Due to their unique properties, microelectromechanical systems (MEMS technology has been recently engineered as implantable drug delivery systems for disease therapy. This review examines the challenges faced in implementing implantable MEMS drug delivery systems in vivo and the solutions available to overcome these challenges.

  4. Implantable Microimagers

    Directory of Open Access Journals (Sweden)

    Jun Ohta

    2008-05-01

    Full Text Available Implantable devices such as cardiac pacemakers, drug-delivery systems, and defibrillators have had a tremendous impact on the quality of live for many disabled people. To date, many devices have been developed for implantation into various parts of the human body. In this paper, we focus on devices implanted in the head. In particular, we describe the technologies necessary to create implantable microimagers. Design, fabrication, and implementation issues are discussed vis-à-vis two examples of implantable microimagers; the retinal prosthesis and in vivo neuro-microimager. Testing of these devices in animals verify the use of the microimagers in the implanted state. We believe that further advancement of these devices will lead to the development of a new method for medical and scientific applications.

  5. The Pathology of Orthopedic Implant Failure Is Mediated by Innate Immune System Cytokines

    Directory of Open Access Journals (Sweden)

    Stefan Landgraeber

    2014-01-01

    Full Text Available All of the over 1 million total joint replacements implanted in the US each year are expected to eventually fail after 15–25 years of use, due to slow progressive subtle inflammation at the bone implant interface. This inflammatory disease state is caused by implant debris acting, primarily, on innate immune cells, that is, macrophages. This slow progressive pathological bone loss or “aseptic loosening” is a potentially life-threatening condition due to the serious complications in older people (>75 yrs of total joint replacement revision surgery. In some people implant debris (particles and ions from metals can influence the adaptive immune system as well, giving rise to the concept of metal sensitivity. However, a consensus of studies agrees that the dominant form of this response is due to innate reactivity by macrophages to implant debris where both danger (DAMP and pathogen (PAMP signalling elicit cytokine-based inflammatory responses. This paper discusses implant debris induced release of the cytokines and chemokines due to activation of the innate (and the adaptive immune system and the subsequent formation of osteolysis. Different mechanisms of implant-debris reactivity related to the innate immune system are detailed, for example, danger signalling (e.g., IL-1β, IL-18, IL-33, etc., toll-like receptor activation (e.g., IL-6, TNF-α, etc., apoptosis (e.g., caspases 3–9, bone catabolism (e.g., TRAP5b, and hypoxia responses (Hif1-α. Cytokine-based clinical and basic science studies are in progress to provide diagnosis and therapeutic intervention strategies.

  6. The results of cataract nigra cases operated with the mini-nuc technique.

    Science.gov (United States)

    Yuzbasioglu, Erdal; Helvacioglu, Firat; Tugcu, Betul; Terzi, Nazire; Keskinbora, Kadircan

    2009-12-01

    The purpose of this study was to evaluate the efficacy and safety of the mini-nuc technique for the removal of brunescent and black cataracts. A prospective study was carried out in 33 eyes of 33 patients with cataract nigra operated with the mini-nuc technique between April 2002 and June 2003. Slit-lamp examinations, intraocular pressure (IOP) measurements, and best-corrected visual acuity (BCVA) were assessed pre- and postoperatively. Accompanying systemic diseases were noted. Intraoperative and postoperative complications were evaluated. Unilateral eyes of 33 patients (18 male [54.5%], 15 female [45.5%]) aged between 65 and 90 years (mean 72 years) were operated with the mini-nuc technique. Preoperative BCVA values varied between light perception and 0.2 in the Snellen chart. Intraocular lenses (IOL) were implanted into all of the patients (27 in-the-bag [81.8%], four to sulcus [12.1%], and two with scleral fixation [6.1%]). During the surgery, five patients (15.15%) had zonular dialysis and two (6.1%) had posterior capsule rupture and vitreous loss. Postoperatively, three (9.1%) rises in IOP, two (6.1%) hyphema, and one (3%) IOL subluxation were observed. At the first day visit, the mean of the uncorrected visual acuities (UCVA) was 0.5 in the Snellen chart. At the third month visit, the mean BCVA was observed to be 0.8. The residual mean astigmatism was 0.75 D against the rule. The mini-nuc technique was effective in removing brunescent and black cataracts with a low rate of serious complications. The mini-nuc technique, which is also performed with a small incision and without sutures, might be an alternative to phacoemulsification in cases of cataract nigra.

  7. Phonological systems of pediatric cochlear implant users: The acquisition of voicing

    Science.gov (United States)

    Chin, Steven B.; Oglesbee, Eric N.; Kirk, Andrew K.; Krug, Joseph E.

    2005-04-01

    Although cochlear implants are primarily auditory prostheses, they have also demonstrated their usefulness as aids to speech production and the acquisition of spoken language in children. This presentation reports on research currently being conducted at the Indiana University Medical Center on the development of phonological systems by children with five or more years of cochlear implant use in English-speaking environments. Characteristics of the feature [voice] will be examined in children with cochlear implants and in two comparison groups: adults with normal hearing and children with normal hearing. Specific aspects of voicing to be discussed include characteristic error patterns, phonetic implementation of the voicing contrast, and phonetic implementation of neutralization of the voicing contrast. Much of the evidence obtained thus far indicates that voicing acquisition in children with cochlear implants is not radically different from that of children with normal hearing. Many differences between the systems of children with cochlear implants and the ambient system thus appear to reflect the children's age as much as their hearing status. [Work supported by grants from the National Institutes of Health to Indiana University: R01DC005594 and R03DC003852.

  8. Periodontal ligament formation around different types of dental titanium implants. I. The self-tapping screw type implant system

    DEFF Research Database (Denmark)

    Warrer, K; Karring, T; Gotfredsen, K

    1993-01-01

    The aim of this study was to determine if a periodontal ligament can form around self-tapping, screw type titanium dental implants. Implants were inserted in contact with the periodontal ligament of root tips retained in the mandibular jaws of 7 monkeys. In each side of the mandible, 1 premolar......, a periodontal ligament can form on self-tapping, screw type titanium dental implants in areas where a void is present between the surrounding bone and the implant at the time of insertion....... and 2 molars were removed in such a manner that in approximately half the cases, the root tips were retained. Following healing, the experimental areas were examined on radiographs, and sites were selected for the insertion of the implants, so that every second implant would have a close contact...

  9. Casework testing of the multiplex kits AmpFlSTR SEfiler Plus PCR amplification kit (AB), PowerPlex S5 System (Promega) and AmpFlSTR MiniFiler PCR amplification kit (AB).

    Science.gov (United States)

    Müller, Kathrin; Sommerer, Thomas; Miltner, Erich; Schneider, Harald; Wiegand, Peter

    2010-04-01

    The short tandem repeat (STR) kits SEfiler Plus (D3S1358, FGA, D8S1179, D18S51, D21S11, TH01, VWA, SE33, D2S1338, D16S539, D19S433 and Amelogenin), PowerPlex S5 System (D18S51, D8S1179, TH01, FGA and Amelogenin) and MiniFiler (D13S317, D7S820, Amelogenin, D2S1338, D21S11, D16S539, D18S51, CSF1PO and FGA) were comparatively tested for their robustness and sensitivity. About 50 stains with highly degraded DNA and little DNA quantity served as examination material (e.g., hair with a telogen root, bones, degraded saliva stains on drinking vessels and skin cell mixtures). The PowerPlex S5 with five German DNA database (DAD) systems and the MiniFiler kit with four topical DAD systems and further STR markers show reduced amplicon lengths. The SEfiler Plus kit represents no MiniSTR multiplex, but contains the nine current DAD systems and further three systems D2S1338, D16S539 and D19S433, which are the potential expansion markers for the German DNA database. We have found on the basis of our comparative stain investigations, that the SEfiler Plus kit was less sensitive than the PowerPlex S5 and the MiniFiler kits. The MiniFiler and the PowerPlex S5 kit showed comparatively high sensitivity. Especially in analysing skin cell mixtures, the MiniFiler kit showed larger differences with regard to the performance of the fluorescent dyes/primer concentration co-ordination than the PowerPlex S5. The SEfiler Plus kit generated - just as both MiniSTR kits - relative robust typing results, but there appeared an increased sensitivity for 'allelic drop-outs' and 'imbalances'. Since the SEfiler Plus kit was not planned as MiniSTR concept, 'allelic drop-outs' were observed, as expected, more frequent in typing stains with degraded DNA and little DNA quantity, especially in the long polymerase chain reaction (PCR) products (e.g., D18S51).

  10. Periodontal ligament formation around different types of dental titanium implants. I. The self-tapping screw type implant system

    DEFF Research Database (Denmark)

    Warrer, K; Karring, T; Gotfredsen, K

    1993-01-01

    The aim of this study was to determine if a periodontal ligament can form around self-tapping, screw type titanium dental implants. Implants were inserted in contact with the periodontal ligament of root tips retained in the mandibular jaws of 7 monkeys. In each side of the mandible, 1 premolar......, a periodontal ligament can form on self-tapping, screw type titanium dental implants in areas where a void is present between the surrounding bone and the implant at the time of insertion....

  11. Mini Courses Without Maxi Headaches

    Science.gov (United States)

    Carhart, R. David; Carney, Loretta

    1974-01-01

    "The Principal," a publication of the School Administration Association of New York State, contains this article clarifying goals for the organizational change involved in instituting mini courses and providing suggestions for successful mini course implementation. (JH)

  12. Systemic antibiotics and the risk of superinfection in peri-implantitis.

    Science.gov (United States)

    Verdugo, Fernando; Laksmana, Theresia; Uribarri, Agurne

    2016-04-01

    Peri-implantitis has emerged in the last few years as a complication difficult to resolve. The etiopathogenesis consensus is mainly attributed to bacteria. Following the preferred reporting items for systematic reviews and meta-analysis (PRISMA) guidelines, a PubMed/Medline literature search was performed using the US National Library of Medicine database up to 2015 to analyze available scientific data on the rationale and risk of superinfection associated to systemic antimicrobials in human peri-implant disease. A hand search was also conducted on relevant medical and microbiology journals. The methodological index for non-randomized studies (MINORS) was independently assessed for quality on the selected papers. Proposed combined therapies use broad-spectrum antibiotics to halt the disease progression. A major associated risk, particularly when prescribed empirically without microbiological follow-up, is the undetected development of superinfections and overgrowth of opportunistic pathogens difficult to eradicate. Peri-implant superinfections with opportunistic bacteria, yeast and viruses, are plausible risks associated to the use of systemic antibiotics in immunocompetent individuals. Lack of microbiological follow-up and antibiotic susceptibility testing may lead to ongoing microbial challenges that exacerbate the disease progression. The increased proliferation of antimicrobial resistance, modern implant surface topography and indiscriminative empiric antibiotic regimens may promote the escalation of peri-implant disease in years to come. A personalized 3-month supportive therapy may help prevent risks by sustaining a normal ecological balance, decreasing specific pathogen proportions and maintaining ideal plaque control. Copyright © 2015 Elsevier Ltd. All rights reserved.

  13. Implementation of wireless power transfer and communications for an implantable ocular drug delivery system.

    Science.gov (United States)

    Tang, T B; Smith, S; Flynn, B W; Stevenson, J T M; Gundlach, A M; Reekie, H M; Murray, A F; Renshaw, D; Dhillon, B; Ohtori, A; Inoue, Y; Terry, J G; Walton, A J

    2008-09-01

    A wireless power transfer and communication system based on near-field inductive coupling has been designed and implemented. The feasibility of using such a system to remotely control drug release from an implantable drug delivery system is addressed. The architecture of the wireless system is described and the signal attenuation over distance in both water and phosphate buffered saline is studied. Additionally, the health risk due to exposure to radio frequency (RF) radiation is examined using a biological model. The experimental results demonstrate that the system can trigger the release of drug within 5 s, and that such short exposure to RF radiation does not produce any significant (system could replace a chemical battery in an implantable system, eliminating the risks associated with battery failure and leakage and also allowing more compact designs for applications such as drug delivery.

  14. Mini mental state examination

    DEFF Research Database (Denmark)

    Kørner, Ejnar Alex; Lauritzen, Lise; Wang, August;

    2008-01-01

    INTRODUCTION: The Mini Mental State Examination (MMSE) is widely used in Denmark, but often in non-validated versions. In 2000 a cross-sectional workgroup decided on a new common version of the MMSE with a corresponding manual, which is validated for the first time in the present study. MATERIALS...

  15. Mini Project Programming Exams

    DEFF Research Database (Denmark)

    Nørmark, Kurt; Thomsen, Lone Leth; Torp, Kristian

    2008-01-01

    A number of different types of final programming exams used or considered at the Department of Computer Science, Aalborg University, are identified and analyzed. Based on this analysis, a new type of programming exam is introduced called a Mini Project Programming (MIP) exam. MIP is a group-based...... of MIP is how to detect fraud....

  16. Electrostatic acceleration and deflection system for modification of semiconductor materials in laser-produced ion implantation

    Science.gov (United States)

    Rosinski, M.; Parys, P.; Wolowski, J.; Gasior, P.; Pisarek, M.

    2010-10-01

    To optimize the efficiency of laser ion implantation technology, it is advisable to properly select the laser beam characteristics (i.e. power density, target illumination geometry, etc.). In many applications, it is important to select a specific range of ion energy to implant the ions at a given depth and at a given density. To make it possible, the electrostatic system for acceleration and deflection of low-energy laser-produced ions can be used. This contribution provides a description of the experiments aimed at the implantation of Ge ions from a narrow energy band onto SiO2/Si substrates, which were conducted at IPPLM. As the source of irradiation, we used a Nd:YAG up to 10 Hz laser system with pulse duration of 3.5 ns and pulse energy ∼ 0.5 J, which gave a power density of 1010 W/cm2. The ion stream parameters were measured using the time-of-fight method. The laser-produced ions passing through the diaphragm have been accelerated in the system of electrodes. Due to the electrostatic field configuration provided by the electrode system and a diaphragm located at the axis of the system, the selected ions were focussed at the area of interest to increase implantation density. The accelerating voltage, the distance of the diaphragm from the target, the diaphragm diameter and the gap width between electrodes were changed for choosing the desired parameters of the ion stream.

  17. Investigation of Self-Assembly Processes for Chitosan-Based Coagulant-Flocculant Systems: A Mini-Review

    Directory of Open Access Journals (Sweden)

    Savi Bhalkaran

    2016-09-01

    Full Text Available The presence of contaminants in wastewater poses significant challenges to water treatment processes and environmental remediation. The use of coagulation-flocculation represents a facile and efficient way of removing charged particles from water. The formation of stable colloidal flocs is necessary for floc aggregation and, hence, their subsequent removal. Aggregation occurs when these flocs form extended networks through the self-assembly of polyelectrolytes, such as the amine-based polysaccharide (chitosan, which form polymer “bridges” in a floc network. The aim of this overview is to evaluate how the self-assembly process of chitosan and its derivatives is influenced by factors related to the morphology of chitosan (flocculant and the role of the solution conditions in the flocculation properties of chitosan and its modified forms. Chitosan has been used alone or in conjunction with a salt, such as aluminum sulphate, as an aid for the removal of various waterborne contaminants. Modified chitosan relates to grafted anionic or cationic groups onto the C-6 hydroxyl group or the amine group at C-2 on the glucosamine monomer of chitosan. By varying the parameters, such as molecular weight and the degree of deacetylation of chitosan, pH, reaction and settling time, dosage and temperature, self-assembly can be further investigated. This mini-review places an emphasis on the molecular-level details of the flocculation and the self-assembly processes for the marine-based biopolymer, chitosan.

  18. Laser-Modified Surface Enhances Osseointegration and Biomechanical Anchorage of Commercially Pure Titanium Implants for Bone-Anchored Hearing Systems.

    Science.gov (United States)

    Shah, Furqan A; Johansson, Martin L; Omar, Omar; Simonsson, Hanna; Palmquist, Anders; Thomsen, Peter

    2016-01-01

    Osseointegrated implants inserted in the temporal bone are a vital component of bone-anchored hearing systems (BAHS). Despite low implant failure levels, early loading protocols and simplified procedures necessitate the application of implants which promote bone formation, bone bonding and biomechanical stability. Here, screw-shaped, commercially pure titanium implants were selectively laser ablated within the thread valley using an Nd:YAG laser to produce a microtopography with a superimposed nanotexture and a thickened surface oxide layer. State-of-the-art machined implants served as controls. After eight weeks' implantation in rabbit tibiae, resonance frequency analysis (RFA) values increased from insertion to retrieval for both implant types, while removal torque (RTQ) measurements showed 153% higher biomechanical anchorage of the laser-modified implants. Comparably high bone area (BA) and bone-implant contact (BIC) were recorded for both implant types but with distinctly different failure patterns following biomechanical testing. Fracture lines appeared within the bone ~30-50 μm from the laser-modified surface, while separation occurred at the bone-implant interface for the machined surface. Strong correlations were found between RTQ and BIC and between RFA at retrieval and BA. In the endosteal threads, where all the bone had formed de novo, the extracellular matrix composition, the mineralised bone area and osteocyte densities were comparable for the two types of implant. Using resin cast etching, osteocyte canaliculi were observed directly approaching the laser-modified implant surface. Transmission electron microscopy showed canaliculi in close proximity to the laser-modified surface, in addition to a highly ordered arrangement of collagen fibrils aligned parallel to the implant surface contour. It is concluded that the physico-chemical surface properties of laser-modified surfaces (thicker oxide, micro- and nanoscale texture) promote bone bonding which

  19. Local and systemic changes associated with long-term, percutaneous, static implantation with titanium alloys in rhesus macaques (Macaca mulatta)

    Energy Technology Data Exchange (ETDEWEB)

    Frydman, Galit F.; Marini, Robert P.; Bakthavatchalu, Vasudevan; Biddle, Kathleen; Muthupalani, Sureshkumar; Vanderburg, Charles R.; Lai, Barry; Bendapudi, Pavan K.; Tompkins, Ronald G.; Fox, James G.

    2017-04-01

    Metal alloys are frequently used as implant materials in veterinary medicine. Recent studies suggest that many types of metal alloys may induce both local and systemic inflammatory responses. In this study, 37 rhesus macaques with long-term skull-anchored percutaneous titanium alloy implants (0-14 years duration) were evaluated for changes in their hematology, coagulation and serum chemistry profiles. Negative controls (n=28) did not have implants. All of the implanted animals were on IACUC-approved protocols and were not implanted for the purpose of this study. Animals with implants had significantly higher plasma D-dimer and lower antithrombin III concentrations compared with nonimplanted animals (p-values < 0.05). Additionally, animals with implants had significantly higher globulin, and lower albumin and calcium concentrations compared with nonimplanted animals (p-values < 0.05). Many of these changes were positively correlated with duration of implantation as well as the number of implants. Chronic bacterial infection was observed on the skin around many of the implant sites, and within deeper tissues. Representative histopathology around the implant site of two implanted animals revealed chronic suppurative to pyogranulomatous inflammation extending from the skin to the dura mater. X-ray fluorescence microscopy of tissue biopsies from the implant site of the same two animals revealed significant increases in free metal ions within the tissue, including titanium and iron. Free metal ions persisted in the tissues up to 6 months postexplant. These results suggest that long-term skull-anchored percutaneous titanium alloy implants results in localized inflammation, chronic infection, and leaching of metal ions into local tissues.

  20. Suitability of gas flare locations for Mini Gas-To-Liquid Technology ...

    African Journals Online (AJOL)

    Sultan

    Site suitability analysis for Mini Gas-to-liquid (MiniGTL) deployment was carried out for gas flaring ( GF) .... Petroleum Company (Kahle Intelligence ... the pipeline in tapping the vast gas resources of .... decision support system to identify sites.

  1. In-situ forming composite implants for periodontitis treatment: How the formulation determines system performance.

    Science.gov (United States)

    Do, M P; Neut, C; Metz, H; Delcourt, E; Mäder, K; Siepmann, J; Siepmann, F

    2015-01-01

    Periodontitis is the primary cause of tooth loss in adults and a very wide-spread disease. Recently, composite implants, based on a drug release rate controlling polymer and an adhesive polymer, have been proposed for an efficient local drug treatment. However, the processes involved in implant formation and the control of drug release in these composite systems are complex and the relationships between the systems' composition and the implants' performance are yet unclear. In this study, advanced characterization techniques (e.g., electron paramagnetic resonance, EPR) were applied to better understand the in-situ forming implants based on: (i) different types of poly(lactic-co-glycolic acid) (PLGA) as drug release rate controlling polymers; (ii) hydroxypropyl methylcellulose (HPMC) as adhesive polymer; and (iii) doxycycline or metronidazole as drugs. Interestingly, HPMC addition to shorter chain PLGA slightly slows down drug release, whereas in the case of longer chain PLGA the release rate substantially increases. This opposite impact on drug release was rather surprising, since the only difference in the formulations was the polymer molecular weight of the PLGA. Based on the physico-chemical analyses, the underlying mechanisms could be explained as follows: since longer chain PLGA is more hydrophobic than shorter chain PLGA, the addition of HPMC leads to a much more pronounced facilitation of water penetration into the system (as evidenced by EPR). This and the higher polymer lipophilicity result in more rapid PLGA precipitation and a more porous inner implant structure. Consequently, drug release is accelerated. In contrast, water penetration into formulations based on shorter chain PLGA is rather similar in the presence and absence of HPMC and the resulting implants are much less porous than those based on longer chain PLGA. Copyright © 2015 Elsevier B.V. All rights reserved.

  2. EX-VIVO DESIGN EVALUATION OF AN IMPLANTABLE BLOOD PORT SYSTEM

    NARCIS (Netherlands)

    HOEKSTRA, A; ELSTRODT, JM

    1995-01-01

    A prototype of a totally implantable vascular catheter-port system was evaluated on its design using three animals of different species. The catheter was placed either intravenously or intra-arterially, and connected to the port which was retained outside the body. Parameters used for design evaluat

  3. Effects of an alert system on implantable cardioverter defibrillator-related anxiety

    DEFF Research Database (Denmark)

    Duru, Firat; Dorian, Paul; Favale, Stefano

    2010-01-01

    Implantable cardioverter defibrillators (ICD) can prevent sudden cardiac death by delivering high-energy shocks in patients at risk of life-threatening ventricular tachyarrhythmias. Patients may be anxious about receiving inappropriate shocks in case of device or lead system malfunction, or about...

  4. Clinical experience with a novel subcutaneous implantable defibrillator system in a single center

    NARCIS (Netherlands)

    L. Dabiri Abkenari (Lara); D.A.M.J. Theuns (Dominic); S.D.A. Valk (Suzanne); Y. van Belle (Yves); N. de Groot (Natasja); D. Haitsma (David); A. Muskens-Heemskerk (Agnes); T. Szili-Torok (Tamas); L.J.L.M. Jordaens (Luc)

    2011-01-01

    textabstractBackground: Implantable cardioverter-defibrillators (ICDs) reduce mortality in both primary and secondary prevention, but are associated with substantial short- and long-term morbidity. A totally subcutaneous ICD (S-ICD) system has been developed. We report the initial clinical

  5. The systemic inflammatory response syndrome predicts short-term outcome after transapical transcatheter aortic valve implantation

    NARCIS (Netherlands)

    Rettig, Thijs C D; Rigter, Sander; Nijenhuis, Vincent J.; Van Kuijk, Jan Peter; Ten Berg, Jurriën M.; Heijmen, Robin H.; Van De Garde, Ewoudt M W; Noordzij, Peter G.

    2015-01-01

    Objective Despite the minimally invasive nature of transcatheter aortic valve implantation (TAVI), the incidence of acute kidney injury (AKI) and mortality is of major concern. Several studies showed that outcome was influenced by the systemic inflammatory response syndrome (SIRS) in patients underg

  6. Evaluation of biofouling for implantable micro dialysis system.

    Science.gov (United States)

    Ota, T; To, N; Kanno, Y; Miki, N

    2016-08-01

    Implantable artificial kidney can drastically improve the quality of life of the renal disease patients. In previous study, our group has developed a multi-layered micro dialysis device which is composed of micro stainless steel channels and nano-porous polyethersulfone (PES) membranes. The device conducts hemofiltration without dialysis fluids, which is advantageous in miniaturization. We investigated the water-permeability of the PES membrane through in vivo experiments using rat model of renal disease for 5 hours and verified the effectiveness of the device. We investigated the permeability of PES membrane via in vitro experiments for 24 days. Biofouling on the PES membrane was found and caused deterioration of dialysis performance of the membrane. In this research, we investigated the biofouling such as thrombus, coagulation and protein adhesion on the sidewall of the micro fluidic channels. We investigated the micro fluidic channel geometry and surface condition associated with the processing methods. Conducting in vitro experiment for 7 days, biofouling was found to be mainly caused by the surface conditions. The mirror surface formed by electrolytic etching could substantially prevent biofouling.

  7. Enclosed Electronic System for Force Measurements in Knee Implants

    Directory of Open Access Journals (Sweden)

    David Forchelet

    2014-08-01

    Full Text Available Total knee arthroplasty is a widely performed surgical technique. Soft tissue force balancing during the operation relies strongly on the experience of the surgeon in equilibrating tension in the collateral ligaments. Little information on the forces in the implanted prosthesis is available during surgery and post-operative treatment. This paper presents the design, fabrication and testing of an instrumented insert performing force measurements in a knee prosthesis. The insert contains a closed structure composed of printed circuit boards and incorporates a microfabricated polyimide thin-film piezoresistive strain sensor for each condylar compartment. The sensor is tested in a mechanical knee simulator that mimics in-vivo conditions. For characterization purposes, static and dynamic load patterns are applied to the instrumented insert. Results show that the sensors are able to measure forces up to 1.5 times body weight with a sensitivity fitting the requirements for the proposed use. Dynamic testing of the insert shows a good tracking of slow and fast changing forces in the knee prosthesis by the sensors.

  8. Fabrication of Co/CoO Exchange Bias System by Ion Implantation and Its Magnetic Properties

    Institute of Scientific and Technical Information of China (English)

    FA Tao; XIANG Qing-Pei; YAO Shu-De

    2009-01-01

    We use ion implantation as a new approach to build an anti-ferromagnetic(AFM)cluster embedded exchange bias(EB)system.Co film with thickness of 130nm is deposited on the Si(111)substrate using magnetron sputtering,60keV O~+ is chosen to implanted into the Co film to form CoO AFM clusters coupling with Co matrix at the interface.By measuring the hysteresis loop after Reid-cooling,significant shifts of loop along the applied field are confirmed.When increasing the implantation dose to 2×10~(17)/cm~2 and annealed samples in N2 atmosphere,we obtain the highest HEB to 458 Oe.

  9. Flexible multi-electrode array with integrated bendable CMOS-chip for implantable systems.

    Science.gov (United States)

    Winkin, N; Mokwa, W

    2012-01-01

    Micro-electrodes and micro-electrode arrays (MEAs) for stimulating neurons or recording action potentials are widely used in medical applications or biological research. For medical implants in many applications like brain implants or retinal implants there is a need for flexible MEAs with a large area and a large number of stimulation electrodes. In this work a flexible MEA with an embedded flexible silicon dummy CMOS-chip facing these challenges has been designed, manufactured and characterized. This approach offers the possibility by connecting and addressing several of these MEAs via a bus system, to increase the number and the density of electrodes significantly. This paper describes the design and fabrication process. Results on the mechanical and electrical behavior will be given and possible improvements for medical applications by this novel approach will be discussed.

  10. Depth of valve implantation, conduction disturbances and pacemaker implantation with CoreValve and CoreValve Accutrak system for Transcatheter Aortic Valve Implantation, a multi-center study.

    Science.gov (United States)

    Lenders, Guy D; Collas, Valérie; Hernandez, José Maria; Legrand, Victor; Danenberg, Haim D; den Heijer, Peter; Rodrigus, Inez E; Paelinck, Bernard P; Vrints, Christiaan J; Bosmans, Johan M

    2014-10-20

    Transcatheter Aortic Valve Implantation (TAVI) is now considered an indispensable treatment strategy in high operative risk patients with severe, symptomatic aortic stenosis. However, conduction disturbances and the need for Permanent Pacemaker (PPM) implantation after TAVI with the CoreValve prosthesis still remain frequent. We aimed to evaluate the implantation depth, the incidence and predictors of new conduction disturbances, and the need for PPM implantation within the first month after TAVI, using the new Accutrak CoreValve delivery system (ACV), compared to the previous generation CoreValve (non-ACV). In 5 experienced TAVI-centers, a total of 120 consecutive non-ACV and 112 consecutive ACV patients were included (n=232). The mean depth of valve implantation (DVI) was 8.4±4.0 mm in the non-ACV group and 7.1±4.0 mm in the ACV group (p=0.034). The combined incidence of new PPM implantation and new LBBB was 71.2% in the non-ACV group compared to 50.5% in the ACV group (p=0.014). DVI (p=0.002), first degree AV block (p=0.018) and RBBB (p<0.001) were independent predictors of PPM implantation. DVI (p<0.001) and pre-existing first degree AV-block (p=0.021) were identified as significant predictors of new LBBB. DVI is an independent predictor of TAVI-related conduction disturbances and can be reduced by using the newer CoreValve Accutrak delivery system, resulting in a significantly lower incidence of new LBBB and new PPM implantation. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  11. Análisis microestructural de cinco sistemas de implantes de titanio comercialmente puro Microstructural analysis of five commercially pure titanium implant systems

    Directory of Open Access Journals (Sweden)

    S. Olate

    2010-04-01

    Full Text Available Hoy en día existe un gran número de empresas fabricantes de implantes así como diferentes tipos de implantes, lo que ha llevado a la diversificación en las técnicas de producción, no siempre asociados a una mejor calidad. El objetivo de este estudio fue identificar y tipificar cinco implantes de titanio comercialmente puro. Se utilizó un estudio descriptivo, doble ciego, para estudiar 15 muestras de implantes de 5 empresas comerciales. Cada implante fue removido de su transporte manteniendo sus características originales. Cada grupo fue de cinco implantes, nombrados con las letras A, B, C, D y E. el análisis incluyó metalografia, microscopia electrónica con sistema de microanálisis (SEM-EDS y finalmente, un analizador de imágenes. Implamed® y Master Screw® mostraron granos de menor tamaño. En microfotografías, todos exhibieron picos de titanio, carbono y oxígeno. Implamed® mostró también acero, sodio, magnesio, silicona, potasio e inclusiones de calcio. Todas las muestras mostraron buena finalización. Las variaciones observadas no serían suficientes para interferir en el proceso de oseointegración, no obstante las inclusiones de metal deben ser estudiadas detalladamente en sus efectos a largo plazo.Nowadays there is a great number of manufacturers and types of implants which has led to several techniques in their production, not always associated with better quality. The aim of this research was identify and typify five commercially pure titanium implant systems. A double-blind, descriptive trial was used with the selection of 15 samples from 5 different manufacturers. Each implant was removed from its package keeping its original characteristics. Five implant groups of 3 elements each were formed and named A, B, C, D, and E. The analyses included metallography, scanning electron microscopy with a microanalysis system (SEM-EDS and, finally, an image analyzer. Implamed® and Master Screw® showed smaller grain sizes. In

  12. Quality Assurance Framework for Mini-Grids

    Energy Technology Data Exchange (ETDEWEB)

    Baring-Gould, Ian [National Renewable Energy Lab. (NREL), Golden, CO (United States); Burman, Kari [National Renewable Energy Lab. (NREL), Golden, CO (United States); Singh, Mohit [National Renewable Energy Lab. (NREL), Golden, CO (United States); Esterly, Sean [National Renewable Energy Lab. (NREL), Golden, CO (United States); Mutiso, Rose [US Department of Energy, Washington, DC (United States); McGregor, Caroline [US Department of Energy, Washington, DC (United States)

    2016-11-01

    Providing clean and affordable energy services to the more than 1 billion people globally who lack access to electricity is a critical driver for poverty reduction, economic development, improved health, and social outcomes. More than 84% of populations without electricity are located in rural areas where traditional grid extension may not be cost-effective; therefore, distributed energy solutions such as mini-grids are critical. To address some of the root challenges of providing safe, quality, and financially viable mini-grid power systems to remote customers, the U.S. Department of Energy (DOE) teamed with the National Renewable Energy Laboratory (NREL) to develop a Quality Assurance Framework (QAF) for isolated mini-grids. The QAF for mini-grids aims to address some root challenges of providing safe, quality, and affordable power to remote customers via financially viable mini-grids through two key components: (1) Levels of service: Defines a standard set of tiers of end-user service and links them to technical parameters of power quality, power availability, and power reliability. These levels of service span the entire energy ladder, from basic energy service to high-quality, high-reliability, and high-availability service (often considered 'grid parity'); (2) Accountability and performance reporting framework: Provides a clear process of validating power delivery by providing trusted information to customers, funders, and/or regulators. The performance reporting protocol can also serve as a robust monitoring and evaluation tool for mini-grid operators and funding organizations. The QAF will provide a flexible alternative to rigid top-down standards for mini-grids in energy access contexts, outlining tiers of end-user service and linking them to relevant technical parameters. In addition, data generated through implementation of the QAF will provide the foundation for comparisons across projects, assessment of impacts, and greater confidence that

  13. Improving performance via mini-applications.

    Energy Technology Data Exchange (ETDEWEB)

    Crozier, Paul Stewart; Thornquist, Heidi K.; Numrich, Robert W. (University of Minnesota, Minneapolis, MN); Williams, Alan B.; Edwards, Harold Carter; Keiter, Eric Richard; Rajan, Mahesh; Willenbring, James M.; Doerfler, Douglas W.; Heroux, Michael Allen

    2009-09-01

    Application performance is determined by a combination of many choices: hardware platform, runtime environment, languages and compilers used, algorithm choice and implementation, and more. In this complicated environment, we find that the use of mini-applications - small self-contained proxies for real applications - is an excellent approach for rapidly exploring the parameter space of all these choices. Furthermore, use of mini-applications enriches the interaction between application, library and computer system developers by providing explicit functioning software and concrete performance results that lead to detailed, focused discussions of design trade-offs, algorithm choices and runtime performance issues. In this paper we discuss a collection of mini-applications and demonstrate how we use them to analyze and improve application performance on new and future computer platforms.

  14. Variable-temperature sample system for ion implantation at -192 to +500/sup 0/C

    Energy Technology Data Exchange (ETDEWEB)

    Fuller, C.T.

    1978-04-01

    A variable-temperature sample system based on exchange-gas coupling was developed for ion-implantation use. The sample temperature can be controlled from -192/sup 0/C to +500/sup 0/C with rapid cooling. The system also has provisions for focusing and alignment of the ion beam, electron suppression, temperature monitoring, sample current measuring, and cryo-shielding. Design considerations and operating characteristics are discussed. 5 figures.

  15. Experimental Validation of an Optical System for Interrogation of Dermally-Implanted Microparticle Sensors

    OpenAIRE

    2009-01-01

    Dermally-implanted microparticle sensors are being developed for on-demand monitoring of blood sugar levels. For these to be deployed in vivo, a matched opto-electronic system for delivery of excitation, collection and analysis of escaping fluorescent signal is needed. Previous studies predicted the characteristics of fluorescence from microparticle sensors to facilitate design of hardware system. Based on the results of simulations, we designed and constructed the optical part of this opto-e...

  16. DNA mini-barcodes.

    Science.gov (United States)

    Hajibabaei, Mehrdad; McKenna, Charly

    2012-01-01

    Conventional DNA barcoding uses an approximately 650 bp DNA barcode of the mitochondrial gene COI for species identification in animal groups. Similar size fragments from chloroplast genes have been proposed as barcode markers for plants. While PCR amplification and sequencing of a 650 bp fragment is consistent in freshly collected and well-preserved specimens, it is difficult to obtain a full-length barcode in older museum specimens and samples which have been preserved in formalin or similar DNA-unfriendly preservatives. A comparable issue may prevent effective DNA-based authentication and testing in processed biological materials, such as food products, pharmaceuticals, and nutraceuticals. In these cases, shorter DNA sequences-mini-barcodes-have been robustly recovered and shown to be effective in identifying majority of specimens to a species level. Furthermore, short DNA regions can be utilized via high-throughput sequencing platforms providing an inexpensive and comprehensive means of large-scale species identification. These properties of mini-barcodes, coupled with the availability of standardized and universal primers make mini-barcodes a feasible option for DNA barcode analysis in museum samples and applied diagnostic and environmental biodiversity analysis.

  17. Aquatic modules for bioregenerative life support systems: Developmental aspects based on the space flight results of the C.E.B.A. Mini Module

    Science.gov (United States)

    Bluem, S. V.

    The Closed Equilibrated Biological Aquatic System (C.E.B.A.S.) is an artificial aquatic ecosystem which contains teleost fishes, water snails, ammonia oxidizing bacteria and edible non-gravitropic water plants. It serves as a model for aquatic food production modules which are not seriously affected by microgravity and other space conditions. Its space flight version, the so-called C.E.B.AS. MINI-MODULE was already successfully tested in the STS-89 and STS 90 (NEUROLAB) missions.- I will be flown a third time in space with the STS 107 mission in July 2002. All- results obtained so far in space indicate that the basic concept of the system is more than suitable to drive forward its development. The C.E.B.A.S. MINI-MODULE is located within a middeck locker whith limited the space for additional components. These technical limitations allow only some modifications which lead to a maximum experiment time span of 120 days which is not long enough for the demanded scientifically essential multi-generation-experiments. This first necessary step is the development of "harvesting devices" for the different organisms. In the limited space of the plant bioreactor a high biomass production leads to self- shadowing effects which results in an uncontrolled degradation and increased oxygen consum ption by microorganisms which will endanger the fishes and snails. It was shown already that the latter reproduce excellently in space and that the reproductive functions of the fishes are not affected. Although the parent - offspring- cannibalism of the used ovoviviparous fish species (Xiphophorus helleri) serves as a regulating factor in population dynamics an uncontrolled snail reproduction will also induce an increased ox gen consumption per se and a high ammonia concentrationy in the water. If harvesting locks can be handled by astronauts in, e. g., 4w e e k- intervals their construction is not very difficult and basic technical solutions are already developed. The second problem is

  18. Aquatic modules for bioregenerative life support systems: Developmental aspects based on the space flight results of the C.E.B.A.S. mini-module

    Science.gov (United States)

    Blüm, V.

    The Closed Equilibrated Biological Aquatic System (C.E.B.A.S.) is an artificial aquatic ecosystem which contains teleost fishes, water snails, ammonia oxidizing bacteria and edible non-gravitropic water plants. It serves as a model for aquatic food production modules which are not seriously affected by microgravity and other space conditions. Its space flight version, the so-called C.E.B.A.S. MINI-MODULE was already successfidly tested in the STS-89 and STS-90 (NEUROLAB) missions. It will be flown a third time in space with the STS-107 mission in January 2003. All results obtained so far in space indicate that the basic concept of the system is more than suitable to drive forward its development. The C.E.B.A.S. MINI-MODULE is located within a middeck locker with limited space for additional components. These technical limitations allow only some modifications which lead to a maximum experiment time span of 120 days which is not long enough for scientifically essential multi-generation-experiments. The first necessary step is the development of "harvesting devices" for the different organisms. In the limited space of the plant bioreactor a high biomass production leads to self-shadowing effects which results in an uncontrolled degradation and increased oxygen consumption by microorganisms which will endanger the fishes and snails. It was shown already that the latter reproduce excellently in space and that the reproductive functions of the fish species are not affected. Although the parent-offspring-cannibalism of the ovoviviparous fish species ( Xiphophorus helleri) serves as a regulating factor in population dynamics an uncontrolled snail reproduction will also induce an increased oxygen consumption per se and a high ammonia concentration in the water. If harvesting locks can be handled by astronauts in, e. g., 4-week intervals their construction is not very difficult and basic technical solutions are already developed. The second problem is the feeding of the

  19. Present status of MiniGRAIL

    NARCIS (Netherlands)

    Ackermann, R.; Benzaim, Y.; Frossati, G.; Gottardi, L.; Karbalai-Sadegh, A.; Reincke, W.; Shumack, A.; Usenko, O.; Waard, de A.; Flokstra, J.; Podt, M.; Bassan, M.; Coccia, E.; Fafone, V.; Minenkov, Y.; Moleti, A.; Pallottino, G.V.; Rocchi, A.; Visco, M.

    2005-01-01

    The latest results of the measurements on the vibration isolation system of MiniGRAIL at room temperature as well as an overview of the results of the ultra-cryogenic tests with the dilution refrigerator are presented. Two types of capacitive transducers have been developed and tested separately in

  20. A detection system for charged-particle decay studies with a continuous-implantation method

    Energy Technology Data Exchange (ETDEWEB)

    Sun, L.J. [China Institute of Atomic Energy, Beijing 102413 (China); Xu, X.X., E-mail: xuxinxing@ciae.ac.cn [China Institute of Atomic Energy, Beijing 102413 (China); Lin, C.J., E-mail: cjlin@ciae.ac.cn [China Institute of Atomic Energy, Beijing 102413 (China); Wang, J.S. [Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000 (China); Fang, D.Q. [Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800 (China); Li, Z.H. [School of Physic and State Key Laboratory of Nuclear Physics and Technology, Peking University, Beijing 100871 (China); Wang, Y.T. [Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800 (China); Li, J. [School of Physic and State Key Laboratory of Nuclear Physics and Technology, Peking University, Beijing 100871 (China); Yang, L.; Ma, N.R. [China Institute of Atomic Energy, Beijing 102413 (China); Wang, K. [Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800 (China); Zang, H.L. [School of Physic and State Key Laboratory of Nuclear Physics and Technology, Peking University, Beijing 100871 (China); Wang, H.W.; Li, C.; Shi, C.Z.; Nie, M.W.; Li, X.F.; Li, H. [Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800 (China); Ma, J.B.; Ma, P. [Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000 (China); and others

    2015-12-21

    A new detection system with high detection efficiency and low detection threshold has been developed for charged-particle decay studies, including β-delayed proton, α decay or direct proton emission from proton-rich nuclei. The performance was evaluated by using the β-delayed proton emitter {sup 24}Si produced by projectile fragmentation at the First Radioactive Ion Beam Line in Lanzhou. Under a continuous-beam mode, the isotopes of interest were implanted into two double-sided silicon strip detectors, where the subsequent decays were measured and correlated to the preceding implantations by using position and time information. The system allows us to measure protons with energies down to about 200 keV without obvious β background in the proton spectrum. Further application of the detection system can be extended to the measurements of β-delayed proton decay and the direct proton emission of more exotic proton-rich nuclei.

  1. 微型种植体支抗压低犬切牙移动过程中牙周牙根骨性组织的变化%Histological changes of tooth root and periodontal tissue during mini-implant anchorage for incisor intrusion in dogs

    Institute of Scientific and Technical Information of China (English)

    葛振林; 卢嘉静; 祁涛; 田佳灵; 杨彩霞

    2011-01-01

    BACKGROUND: Tooth intrusion easily leads to root resorption. Previous studies regarding orthodontic treatment-caused tooth root resorption or retrospective clinical studies based on X-ray films have great errors in outcome evaluation because of intrusion force which cannot be precisely controlled. OBJECTIVE: This study established dog models of mini-implant anchorage for incisor intrusion to observe the histological changes of tooth root and periodontal tissue and to evaluate the feasibility and safety of mini-implant anchorage for incisor intrusion. METHODS: Nine dogs were assigned to one control group (n = 1) and four experimental groups per time to sacrifice (1, 2, 4 and 12 weeks; n = 2 dogs for each experimental group). No force was added to the control group. In the experimental groups, mini-implant as an anchorage was placed in the buccal alveoli between maxillary second and third incisors on each side. A traction force of 100 g was imposed to each side to intrude the maxillary first and second incisors on each side. At 1, 2, 3, and 4 weeks (traction force was imposed for 4 weeks and after withdrawal of extraction force, mini-implant was retained in place for 8 weeks), dogs were sacrificed. The first and second incisors together with gingival and alveolar bone were completely resected to prepare histological specimens. Following hematoxylin-eosin staining, histological changes of tooth root and periodontal tissue were observed. RESULTS AND CONCLUSION: Compared with the control group, in the 1-week group, histological changes were primarily at the root tip and alveolar ridge crest, alveolar bone and cementum were absorbed and peridental membrane presented glassy degeneration in local region; in the 2-week group, bone resorption degree and range were obviously enlarged, and bone resorption developed from root tip, root middle part to cervical part; in the 4-week group, bone resorption was still active and the glassy degeneration of peridental membrane

  2. Development of a flow chamber system for the reproducible in vitro analysis of biofilm formation on implant materials

    Science.gov (United States)

    Rath, Henryke; Stumpp, Sascha Nico; Stiesch, Meike

    2017-01-01

    Since the introduction of modern dental implants in the 1980s, the number of inserted implants has steadily increased. Implant systems have become more sophisticated and have enormously enhanced patients’ quality of life. Although there has been tremendous development in implant materials and clinical methods, bacterial infections are still one of the major causes of implant failure. These infections involve the formation of sessile microbial communities, called biofilms. Biofilms possess unique physical and biochemical properties and are hard to treat conventionally. There is a great demand for innovative methods to functionalize surfaces antibacterially, which could be used as the basis of new implant technologies. Present, there are few test systems to evaluate bacterial growth on these surfaces under physiological flow conditions. We developed a flow chamber model optimized for the assessment of dental implant materials. As a result it could be shown that biofilms of the five important oral bacteria Streptococcus gordonii, Streptococcus oralis, Streptococcus salivarius, Porphyromonas gingivalis, and Aggregatibacter actinomycetemcomitans, can be reproducibly formed on the surface of titanium, a frequent implant material. This system can be run automatically in combination with an appropriate microscopic device and is a promising approach for testing the antibacterial effect of innovative dental materials. PMID:28187188

  3. A power-efficient communication system between brain-implantable devices and external computers.

    Science.gov (United States)

    Yao, Ning; Lee, Heung-No; Chang, Cheng-Chun; Sclabassi, Robert J; Sun, Mingui

    2007-01-01

    In this paper, we propose a power efficient communication system for linking a brain-implantable device to an external system. For battery powered implantable devices, the processor and the transmitter power should be reduced in order to both conserve battery power and reduce the health risks associated with transmission. To accomplish this, a joint source-channel coding/decoding system is devised. Low-density generator matrix (LDGM) codes are used in our system due to their low encoding complexity. The power cost for signal processing within the implantable device is greatly reduced by avoiding explicit source encoding. Raw data which is highly correlated is transmitted. At the receiver, a Markov chain source correlation model is utilized to approximate and capture the correlation of raw data. A turbo iterative receiver algorithm is designed which connects the Markov chain source model to the LDGM decoder in a turbo-iterative way. Simulation results show that the proposed system can save up to 1 to 2.5 dB on transmission power.

  4. 微耕机标准体系的内涵分析及其发展对策%On Connotation Analysis and Development Countermeasures of the Mini-Tiller Standard System

    Institute of Scientific and Technical Information of China (English)

    彭彬; 杨玲; 杨明金; 郭孟报; 叶进; 陈建

    2014-01-01

    Mini-tiller standard system development has positive influence on the production and industry development of mini-tiller.The following regulations have been detailed in the mini-tiller standard system at present in that the items are related to “mini”feature (dimension and scale),to “tilling”feature (tilling quality)and“machine”feature (production quality),to requirements of sign,package,transport and stor-age of the mini-tiller,and to mini-tiller repair technology.Main problems for the standard system are as follows:standard system is not complete;standard content is not perfect;standard terminology is not uni-fied;cutter parameter is not practical;and standard formulation and revision lag behind.Therefore,de-partments in charge of agricultural machinery should pay high attention to the development of mini-tiller standard system,organize and assort with the related factors to further perfect standard content,empha-size the renew and revision of the standard system,and strengthen the popularization and application of the system.%微耕机标准体系建设对微耕机产品生产和产业发展起到十分积极的作用。目前,微耕机标准体系规定了微耕机的“微”(尺寸规格)、“耕”(作业质量)、“机”(产品质量)等方面的内容,以及微耕机的标志、包装、运输和贮存条件及微耕机的修理技术,但还存在标准体系不完整、标准内容不完善、标准术语不统一、刀具参数不具体、标准制定和修订工作滞后等问题,今后农业机械主管部门应高度重视微耕机标准体系建设,组织和协调有关力量进一步完善标准体系内容,注重对标准体系适时补充修订,并加强标准体系的推广应用。

  5. A wireless power transmission system for implantable devices in freely moving rodents.

    Science.gov (United States)

    Eom, Kyungsik; Jeong, Joonsoo; Lee, Tae Hyung; Kim, Jinhyung; Kim, Junghoon; Lee, Sung Eun; Kim, Sung June

    2014-08-01

    Reliable wireless power delivery for implantable devices in animals is highly desired for safe and effective experimental use. Batteries require frequent replacement; wired connections are inconvenient and unsafe, and short-distance inductive coupling requires the attachment of an exterior transmitter to the animal's body. In this article, we propose a solution by which animals with implantable devices can move freely without attachments. Power is transmitted using coils attached to the animal's cage and is received by a receiver coil implanted in the animal. For a three-dimensionally uniform delivery of power, we designed a columnar dual-transmitter coil configuration. A resonator-based inductive link was adopted for efficient long-range power delivery, and we used a novel biocompatible liquid crystal polymer substrate as the implantable receiver device. Using this wireless power delivery system, we obtain an average power transfer efficiency of 15.2% (minimum efficiency of 10% and a standard deviation of 2.6) within a cage of 15×20×15 cm3.

  6. Flexible, Polarization-Diverse UWB Antennas for Implantable Neural Recording Systems.

    Science.gov (United States)

    Bahrami, Hadi; Mirbozorgi, S Abdollah; Ameli, Reza; Rusch, Leslie A; Gosselin, Benoit

    2016-02-01

    Implanted antennas for implant-to-air data communications must be composed of material compatible with biological tissues. We design single and dual-polarization antennas for wireless ultra-wideband neural recording systems using an inhomogeneous multi-layer model of the human head. Antennas made from flexible materials are more easily adapted to implantation; we investigate both flexible and rigid materials and examine performance trade-offs. The proposed antennas are designed to operate in a frequency range of 2-11 GHz (having S11 below -10 dB) covering both the 2.45 GHz (ISM) band and the 3.1-10.6 GHz UWB band. Measurements confirm simulation results showing flexible antennas have little performance degradation due to bending effects (in terms of impedance matching). Our miniaturized flexible antennas are 12 mm×12 mm and 10 mm×9 mm for single- and dual-polarizations, respectively. Finally, a comparison is made of four implantable antennas covering the 2-11 GHz range: 1) rigid, single polarization, 2) rigid, dual polarization, 3) flexible, single polarization and 4) flexible, dual polarization. In all cases a rigid antenna is used outside the body, with an appropriate polarization. Several advantages were confirmed for dual polarization antennas: 1) smaller size, 2) lower sensitivity to angular misalignments, and 3) higher fidelity.

  7. Dose perturbation in the presence of metallic implants: treatment planning system versus Monte Carlo simulations

    Science.gov (United States)

    Wieslander, Elinore; Knöös, Tommy

    2003-10-01

    An increasing number of patients receiving radiation therapy have metallic implants such as hip prostheses. Therefore, beams are normally set up to avoid irradiation through the implant; however, this cannot always be accomplished. In such situations, knowledge of the accuracy of the used treatment planning system (TPS) is required. Two algorithms, the pencil beam (PB) and the collapsed cone (CC), are implemented in the studied TPS. Comparisons are made with Monte Carlo simulations for 6 and 18 MV. The studied materials are steel, CoCrMo, Orthinox® (a stainless steel alloy and registered trademark of Stryker Corporation), TiAlV and Ti. Monte Carlo simulated depth dose curves and dose profiles are compared to CC and PB calculated data. The CC algorithm shows overall a better agreement with Monte Carlo than the PB algorithm. Thus, it is recommended to use the CC algorithm to get the most accurate dose calculation both for the planning target volume and for tissues adjacent to the implants when beams are set up to pass through implants.

  8. Application of high-throughput mini-bioreactor system for systematic scale-down modeling, process characterization, and control strategy development.

    Science.gov (United States)

    Janakiraman, Vijay; Kwiatkowski, Chris; Kshirsagar, Rashmi; Ryll, Thomas; Huang, Yao-Ming

    2015-01-01

    High-throughput systems and processes have typically been targeted for process development and optimization in the bioprocessing industry. For process characterization, bench scale bioreactors have been the system of choice. Due to the need for performing different process conditions for multiple process parameters, the process characterization studies typically span several months and are considered time and resource intensive. In this study, we have shown the application of a high-throughput mini-bioreactor system viz. the Advanced Microscale Bioreactor (ambr15(TM) ), to perform process characterization in less than a month and develop an input control strategy. As a pre-requisite to process characterization, a scale-down model was first developed in the ambr system (15 mL) using statistical multivariate analysis techniques that showed comparability with both manufacturing scale (15,000 L) and bench scale (5 L). Volumetric sparge rates were matched between ambr and manufacturing scale, and the ambr process matched the pCO2 profiles as well as several other process and product quality parameters. The scale-down model was used to perform the process characterization DoE study and product quality results were generated. Upon comparison with DoE data from the bench scale bioreactors, similar effects of process parameters on process yield and product quality were identified between the two systems. We used the ambr data for setting action limits for the critical controlled parameters (CCPs), which were comparable to those from bench scale bioreactor data. In other words, the current work shows that the ambr15(TM) system is capable of replacing the bench scale bioreactor system for routine process development and process characterization.

  9. A CHANDRA-VLA INVESTIGATION OF THE X-RAY CAVITY SYSTEM AND RADIO MINI-HALO IN THE GALAXY CLUSTER RBS 797

    Energy Technology Data Exchange (ETDEWEB)

    Doria, Alberto [Argelander-Institut fuer Astronomie, Auf dem Huegel 71, D-53121 Bonn (Germany); Gitti, Myriam; Brighenti, Fabrizio [Dipartimento di Astronomia, Universita di Bologna, via Ranzani 1, Bologna 40127 (Italy); Ettori, Stefano [Astronomical Observatory of Bologna-INAF, via Ranzani 1, I-40127 Bologna (Italy); Nulsen, Paul E. J.; McNamara, Brian R. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States)

    2012-07-01

    We present a study of the cavity system in the galaxy cluster RBS 797 based on Chandra and Very Large Array (VLA) data. RBS 797 (z = 0.35) is one of the most distant galaxy clusters in which two pronounced X-ray cavities have been discovered. The Chandra data confirm the presence of a cool core and indicate a higher metallicity along the cavity directions. This is likely due to the active galactic nucleus outburst, which lifts cool metal-rich gas from the center along the cavities, as seen in other systems. We find indications that the cavities are hotter than the surrounding gas. Moreover, the new Chandra images show bright rims contrasting with the deep, X-ray deficient cavities. The likely cause is that the expanding 1.4 GHz radio lobes have displaced the gas, compressing it into a shell that appears as bright cool arms. Finally, we show that the large-scale radio emission detected with our VLA observations may be classified as a radio mini-halo, powered by the cooling flow, as it nicely follows the trend P{sub radio} versus P{sub CF} predicted by the reacceleration model.

  10. A Chandra - VLA Investigation of the X-ray Cavity System and Radio Mini-Halo in the Galaxy Cluster RBS 797

    CERN Document Server

    Doria, Alberto; Ettori, Stefano; Brighenti, Fabrizio; Nulsen, Paul E J; McNamara, Brian R

    2012-01-01

    We present a study of the cavity system in the galaxy cluster RBS 797 based on Chandra and VLA data. RBS 797 (z = 0.35), is one of the most distant galaxy clusters in which two pronounced X-ray cavities have been discovered. The Chandra data confirm the presence of a cool core and indicate an higher metallicity along the cavity directions. This is likely due to the AGN outburst, which lifts cool metal-rich gas from the center along the cavities, as seen in other systems. We find indications that the cavities are hotter than the surrounding gas. Moreover, the new Chandra images show bright rims contrasting with the deep, X-ray deficient cavities. The likely cause is that the expanding 1.4 GHz radio lobes have displaced the gas, compressing it into a shell that appears as bright cool arms. Finally we show that the large-scale radio emission detected with our VLA observations may be classified as a radio mini-halo, powered by the cooling flow (CF), as it nicely follows the trend P_radio vs. P_CF predicted by the...

  11. A remote monitoring system for patients with implantable ventricular assist devices with a personal handy phone system.

    Science.gov (United States)

    Okamoto, E; Shimanaka, M; Suzuki, S; Baba, K; Mitamura, Y

    1999-01-01

    The usefulness of a remote monitoring system that uses a personal handy phone for artificial heart implanted patients was investigated. The type of handy phone used in this study was a personal handy phone system (PHS), which is a system developed in Japan that uses the NTT (Nippon Telephone and Telegraph, Inc.) telephone network service. The PHS has several advantages: high-speed data transmission, low power output, little electromagnetic interference with medical devices, and easy locating of patients. In our system, patients have a mobile computer (Toshiba, Libretto 50, Kawasaki, Japan) for data transmission control between an implanted controller and a host computer (NEC, PC-9821V16) in the hospital. Information on the motor rotational angle (8 bits) and motor current (8 bits) of the implanted motor driven heart is fed into the mobile computer from the implanted controller (Hitachi, H8/532, Yokohama, Japan) according to 32-bit command codes from the host computer. Motor current and motor rotational angle data from inside the body are framed together by a control code (frame number and parity) for data error checking and correcting at the receiving site, and the data are sent through the PHS connection to the mobile computer. The host computer calculates pump outflow and arterial pressure from the motor rotational angle and motor current values and displays the data in real-time waveforms. The results of this study showed that accurate data on motor rotational angle and current could be transmitted from the subjects while they were walking or driving a car to the host computer at a data transmission rate of 9600 bps. This system is useful for remote monitoring of patients with an implanted artificial heart.

  12. Accuracy of needle implantation in brachytherapy using a medical AR system: a phantom study

    Science.gov (United States)

    Wesarg, Stefan; Firle, Evelyn A.; Schwald, Bernd; Seibert, Helmut; Zogal, Pawel; Roeddiger, Sandra

    2004-05-01

    Brachytherapy is the treatment method of choice for patients with a tumor relapse after a radiation therapy with external beams or tumors in regions with sensitive surrounding organs-at-risk, e. g. prostate tumors. The standard needle implantation procedure in brachytherapy uses pre-operatively acquired image data displayed as slices on a monitor beneath the operation table. Since this information allows only a rough orientation for the surgeon, the position of the needles has to be verified repeatedly during the intervention. Within the project Medarpa a transparent display being the core component of a medical Augmented Reality (AR) system has been developed. There, pre-operatively acquired image data is displayed together with the position of the tracked instrument allowing a navigated implantation of the brachytherapy needles. The surgeon is enabled to see the anatomical information as well as the virtual instrument in front of the operation area. Thus, the Medarpa system serves as "window into the patient". This paper deals with the results of first clinical trials of the system. Phantoms have been used for evaluating the achieved accuracy of the needle implantation. This has been done by comparing the output of the system (instrument positions relative to the phantom) with the real positions of the needles measured by means of a verification CT scan.

  13. Ultrasound guided implantation of chest port systems via the lateral subclavian vein; Die sonographisch gezielte Implantation von Portkathetersystemen ueber die laterale Vena subclavia

    Energy Technology Data Exchange (ETDEWEB)

    Zaehringer, M.; Hilgers, J.; Krueger, K.; Strohe, D.; Bangard, C.; Neumann, L.; Lackner, K. [Inst. fuer Radiologische Diagnostik, Univ. zu Koeln (Germany); Warm, M. [Gynaekologie, Univ. zu Koeln (Germany); Reiser, M. [Medizinische Klinik I, Univ. zu Koeln (Germany); Toex, U. [Medizinische Klinik IV, Univ. zu Koeln (Germany)

    2006-03-15

    Purpose: Retrospective analysis of the success and complication rates of chest port implantation via the lateral subclavian vein. Materials and methods: Between January 2003 and June 2004, the lateral subclavian vein in 271 patients (186 women, 85 men, mean age 53.2 years) was punctured guided by ultrasound. This access was used to insert a port system, and the catheter tip was placed at the cavoatrial junction. The port reservoir was implanted in a subcutaneous infraclavicular pocket and fixed to the fascia of the pectoralis muscle. Indications for port implantation were chemotherapy (n=239), total parenteral nutrition (n=2) and intravenous medication (n=30). The patient follow-up was mainly performed either by the oncology division of the department of gynecology or by the department of internal medicine. Results: A chest port catheter system was successfully implanted in all patients. The catheter remained in place for a mean duration of 269.4 days (SD 192.3 days). No complications occurred during implantation. In the post-interventional period, 6 catheter dysfunctions were found (thrombotic 0.09 per 1000 catheter days; mechanic 0.05 per 1000 catheter days). While one local infection occurred in the early post-interventional period, 3 local and 15 systemic infections were independent of the port catheter placement (0.39 per 1000 catheter days). The rate of port catheter explantations due to dysfunction or infection was 0.07 per 1000 catheter days. Conclusion: Ultrasound-guided puncture of the lateral subclavian vein is a safe procedure for the insertion of central venous port catheter systems and had a very low complication rate in our study. For further evaluation of our port placement technique, prospective studies compared to placement through the internal jugular vein are necessary. (orig.)

  14. 3-Coil resonance-based wireless power transfer system for implantable electronic

    KAUST Repository

    Yi, Ying

    2013-05-01

    This paper presents a 3-coil resonance-based wireless power transfer (R-WPT) system using a single layer of inductor coil windings, in a pancake configuration, in order to obtain a compact system for implantable electronic applications. A theoretical analysis and experimental measurements in terms of quality factor Q and power transfer efficiency (PTE), was done. Our proposed 3-coil scheme can achieve a high PTE with a resonance frequency of 2.46 MHz over a transfer distance of up to 30 mm, by using two 15-mm radius implant coils. The achieved experimental PTE is more than 85%at a 5 mm separation distance, and about 50% PTE at a distance of 20 mm. © 2013 IEEE.

  15. An image guidance system for positioning robotic cochlear implant insertion tools

    Science.gov (United States)

    Bruns, Trevor L.; Webster, Robert J.

    2017-03-01

    Cochlear implants must be inserted carefully to avoid damaging the delicate anatomical structures of the inner ear. This has motivated several approaches to improve the safety and efficacy of electrode array insertion by automating the process with specialized robotic or manual insertion tools. When such tools are used, they must be positioned at the entry point to the cochlea and aligned with the desired entry vector. This paper presents an image guidance system capable of accurately positioning a cochlear implant insertion tool. An optical tracking system localizes the insertion tool in physical space while a graphical user interface incorporates this with patient- specific anatomical data to provide error information to the surgeon in real-time. Guided by this interface, novice users successfully aligned the tool with an mean accuracy of 0.31 mm.

  16. Gummy smile correction by intruding upper incisors with mini-screw implant: an esthetic evaluation by the golden facial mask%黄金比例面具对种植体支抗压低上切牙改善露龈笑的美学评价初探

    Institute of Scientific and Technical Information of China (English)

    柳大为; 周彦恒; 李韵仪

    2010-01-01

    Objective To use a golden facial mask to classify the gummy smile and then to evaluate the effectiveness of correction gummy smile by intruding upper incisors and canines with mini-screw implants. Methods Sixteen female and 1 male gummy smile patients with an age range of 16-40 years, 26. 2 years on average, were involved in the study. The mini-screw implants were inserted buccally between upper lateral incisors and canines on both sides for intruding upper incisors together with fixed appliance. The golden facial mask was introduced to analyze the frontal view of smile pre- and post-treatment. Results Gummy smile of all patients involved in the study was reduced by intruding upper incisors and canines, and the average period for intruding about 9. 8 months. According to the analysis of the golden facial mask, the reasons of gummy smile in different patients were different before treatment. However, the lips, teeth and gingiva were almost coincident with the golden facial mask after treatment. Conclusions Analyzing the relationship among lip, teeth and gingiva by the golden facial mask, the inprovement of gummy smile by using mini-screw implants to intrude the upper incisors can be evaluated.%目的 利用黄金比例面具对露龈笑进行分类,并评价使用种植体支抗压低上切牙后患者露龈笑的改善程度,探讨种植体支抗压低上切牙治疗露龈笑过程中唇-齿-龈关系的变化趋势.方法 选择17例露龈笑患者,女性16例,男性1例,年龄16~40岁,平均26.2岁.于上颌侧切牙和尖牙间唇侧植入微螺钉种植体支抗压低上切牙,在Photoshop软件中将正面微笑黄金比例面具标准化模板与治疗前后的正面微笑像重叠,比较治疗前后正面微笑像唇、齿、龈在黄金比例面具相应区域内所占比例的变化,定性分析并评价露龈笑的改善程度.结果 17例患者的上切牙均被成功压低,露龈笑明显改善,疗程平均9.8个月.通过黄金比例面具分析发

  17. Comparative study of clinic effects of segmental archs and mini-implants for orthodontic anchorage on orthodontic canine distalization%片段弓与微种植体支抗拉尖牙向远中的临床应用对比研究

    Institute of Scientific and Technical Information of China (English)

    徐晓静; 沈云娟; 秦燕军

    2012-01-01

    Objective To compare the clinic effects of segmental archs and mini-implants for orthodontic anchorage on orthodontic canine distalization. Methods 60 cases of dental crowding, whose four first premolars were extracted and canine distalization was needed according to the treatment protocol, were randomly divided into 2 groups. Mini-implants were used in the cases in experimental group as orthodontic anchorage to move canine distally, and segmental archs were used in the control cases. The distances of canine dis-talizalion and the angles of anchorage molar inclination in 60 cases were measured and compared. Results The mean velocity of canine distalizalion in the experimental group was (1.428 ±0.072) mm/month,which was faster than(l. 137 ±0.081)mm/month in the control group. The degree of molar inclination (1.27 ±0.18) in the experimental group was less than that in the control group (1.91 ±0.13). Statistic analysis showed that there were significant differences. Conclusions The mini-implants for orthodontic anchorage can move the canine faster and control the anchorage molar better than the segmental arch.%目的 比较片段弓技术和微种植体支抗在拉尖牙向远中的临床应用效果.方法 60例牙列拥挤,双侧对称拔除第一前磨牙且需将尖牙拉向远中的患者,随机分为2组,试验组尖牙远移时应用微种植体作为支抗,对照组则使用片段弓技术远移尖牙,测量尖牙向远中移动的距离以及磨牙近中倾斜的程度.结果 试验组尖牙移动的速率为(1.428±0.072)mm/月,快于对照组(1.137±0.081)mm/月;试验组磨牙近中倾斜程度为(1.27±0.18)°,小于对照组(1.91±0.13)°.经统计学检验差异均有显著性(P<0.05).结论 使用微种植体支抗拉尖牙向远中在牙齿移动速率以及控制磨牙近中倾斜等方面优于片段弓技术.

  18. Encapsulated Cellular Implants for Recombinant Protein Delivery and Therapeutic Modulation of the Immune System

    Directory of Open Access Journals (Sweden)

    Aurélien Lathuilière

    2015-05-01

    Full Text Available Ex vivo gene therapy using retrievable encapsulated cellular implants is an effective strategy for the local and/or chronic delivery of therapeutic proteins. In particular, it is considered an innovative approach to modulate the activity of the immune system. Two recently proposed therapeutic schemes using genetically engineered encapsulated cells are discussed here: the chronic administration of monoclonal antibodies for passive immunization against neurodegenerative diseases and the local delivery of a cytokine as an adjuvant for anti-cancer vaccines.

  19. An Implantable Cardiovascular Pressure Monitoring System with On-Chip Antenna and RF Energy Harvesting

    Directory of Open Access Journals (Sweden)

    Yu-Chun Liu

    2015-08-01

    Full Text Available An implantable wireless system with on-chip antenna for cardiovascular pressure monitor is studied. The implantable device is operated in a batteryless manner, powered by an external radio frequency (RF power source. The received RF power level can be sensed and wirelessly transmitted along with blood pressure signal for feedback control of the external RF power. The integrated electronic system, consisting of a capacitance-to-voltage converter, an adaptive RF powering system, an RF transmitter and digital control circuitry, is simulated using a TSMC 0.18 μm CMOS technology. The implanted RF transmitter circuit is combined with a low power voltage-controlled oscillator resonating at 5.8 GHz and a power amplifier. For the design, the simulation model is setup using ADS and HFSS software. The dimension of the antenna is 1 × 0.6 × 4.8 mm3 with a 1 × 0.6 mm2 on-chip circuit which is small enough to place in human carotid artery.

  20. Design of a Customized Multipurpose Nano-Enabled Implantable System for In-Vivo Theranostics

    Directory of Open Access Journals (Sweden)

    Esteve Juanola-Feliu

    2014-10-01

    Full Text Available The first part of this paper reviews the current development and key issues on implantable multi-sensor devices for in vivo theranostics. Afterwards, the authors propose an innovative biomedical multisensory system for in vivo biomarker monitoring that could be suitable for customized theranostics applications. At this point, findings suggest that cross-cutting Key Enabling Technologies (KETs could improve the overall performance of the system given that the convergence of technologies in nanotechnology, biotechnology, micro&nanoelectronics and advanced materials permit the development of new medical devices of small dimensions, using biocompatible materials, and embedding reliable and targeted biosensors, high speed data communication, and even energy autonomy. Therefore, this article deals with new research and market challenges of implantable sensor devices, from the point of view of the pervasive system, and time-to-market. The remote clinical monitoring approach introduced in this paper could be based on an array of biosensors to extract information from the patient. A key contribution of the authors is that the general architecture introduced in this paper would require minor modifications for the final customized bio-implantable medical device.

  1. Biocompatible medical implant materials with binding sites for a biodegradable drug-delivery system

    Directory of Open Access Journals (Sweden)

    Al-Dubai H

    2011-10-01

    Full Text Available Haifa Al-Dubai1, Gisela Pittner1, Fritz Pittner1, Franz Gabor21Max F Perutz Laboratories, Department of Biochemistry, University of Vienna, Vienna, Austria; 2Department of Pharmaceutical Technology and Biopharmaceutics, Faculty of Life Sciences, University of Vienna, Vienna, AustriaAbstract: Feasibility studies have been carried out for development of a biocompatible coating of medical implant materials allowing the binding of biodegradable drug-delivery systems in a way that their reloading might be possible. These novel coatings, able to bind biodegradable nanoparticles, may serve in the long run as drug carriers to mediate local pharmacological activity. After biodegradation of the nanoparticles, the binding sites could be reloaded with fresh drug-delivering particles. As a suitable receptor system for the nanoparticles, antibodies are anchored. The design of the receptor is of great importance as any bio- or chemorecognitive interaction with other components circulating in the blood has to be avoided. Furthermore, the binding between receptor and the particles has to be strong enough to keep them tightly bound during their lifetime, but on the other hand allow reloading after final degradation of the particles. The nanoparticles suggested as a drug-delivery system for medical implants can be loaded with different pharmaceuticals such as antibiotics, growth factors, or immunosuppressives. This concept may enable the changing of medication, even after implantation of the medical device, if afforded by patients’ needs.Keywords: antibody immobilization, biocompatible coating, chitosan nanoparticles, drug targeting, medical device

  2. Breast Implants

    Science.gov (United States)

    ... Medical Procedures Implants and Prosthetics Breast Implants Breast Implants Share Tweet Linkedin Pin it More sharing options Linkedin Pin it Email Print Breast implants are medical devices that are implanted under the ...

  3. Utility of the NavX® Electroanatomic Mapping System for Permanent Pacemaker Implantation in a Pregnant Patient with Chagas Disease

    Directory of Open Access Journals (Sweden)

    Alejandro Velasco, MD

    2013-01-01

    Full Text Available Chagas disease is a highly prevalent zoonosis in Mexico, Central, and South America. Early cardiac involvement is one of the most serious complications of this disease, and conduction disturbances may occur at an early age. We describe a young pregnant woman with Chagas disease and a high degree atrioventricular block, who required implantation of a permanent dual chamber pacemaker. Using an electroanatomic navigation EnSite NavX® system the pacemaker was successfully implanted with minimal fluoroscopic exposure. This case demonstrates the safety and feasibility of using an electroanatomic navigation system to guide permanent pacemaker implantation minimizing x-ray exposure in pregnant patients.

  4. Materials directed to implants for repairing Central Nervous System

    Energy Technology Data Exchange (ETDEWEB)

    Canillas, M.; Moreno-Burriel, B.; Chinarro, E.

    2014-07-01

    Central Nervous System (CNS) can be damaged by a wide range of injuries and disorders which entail permanent disability in some cases. Moreover, CNS repairing process presents some complications. The natural repair mechanism, which consists on the glial scar formation, is triggered by the inflammatory process. Molecules delivered during these processes, inflammation and glial scar formation as well as oxygen and glucose deficiencies due to the injury, create an inhibitory environment for axon regeneration and remyelination which is known as secondary injury. Biomaterials are taking up an even more important role in repairing CNS. Physicochemical properties of some ceramic materials have inspired different applications to repair CNS as substrates, electrodes or molecule vehicles. Based on their biocompatibility, capability to neutralize reactive species involved in the inflammatory processes and their versatile processing to obtain scaffolds with different shapes and sizes, ceramics are a succulent offer in nervous tissue engineering. Furthermore, their possibilities have been increased with polymeric-ceramics composites development, which have given rise to new interesting horizon. (Author)

  5. A configurable realtime DWT-based neural data compression and communication VLSI system for wireless implants.

    Science.gov (United States)

    Yang, Yuning; Kamboh, Awais M; Mason, Andrew J

    2014-04-30

    This paper presents the design of a complete multi-channel neural recording compression and communication system for wireless implants that addresses the challenging simultaneous requirements for low power, high bandwidth and error-free communication. The compression engine implements discrete wavelet transform (DWT) and run length encoding schemes and offers a practical data compression solution that faithfully preserves neural information. The communication engine encodes data and commands separately into custom-designed packet structures utilizing a protocol capable of error handling. VLSI hardware implementation of these functions, within the design constraints of a 32-channel neural compression implant, is presented. Designed in 0.13μm CMOS, the core of the neural compression and communication chip occupies only 1.21mm(2) and consumes 800μW of power (25μW per channel at 26KS/s) demonstrating an effective solution for intra-cortical neural interfaces.

  6. Adaptive evolution at immune system genes and deep pregnancy implantation in primates.

    Science.gov (United States)

    Civetta, Alberto

    2015-01-01

    A major evolutionary change in the lineage ancestral to humans, chimpanzee and gorilla (HCG) has been the embedding of the embryo into maternal tissue. Thus, the first layer of cells (trophoblast) to differentiate after fertilization must adapt to invade the uterus. Such event would likely leave signatures of positive selection at genes with roles in embryo implantation. Here, 163 pregnancy implantation genes are tested for evidence of adaptive diversification in the ancestral lineage to HCG. Two immune system genes, HLA-E and KIR2DL4 showed evidence of positive selection. Some of the positive selected sites involve amino acid substitution with predicted damaging effects on protein function, thus highlighting the possibility of antagonistic pleiotropic effects. Selection at a gene coding for a receptor expressed in uterine cells (KIR) that interacts with trophoblast human leukocyte antigen (HLA) genes suggests a main role for immunological adaptations in embryo deep invasion of the maternal endometrium. Copyright © 2014 Elsevier Inc. All rights reserved.

  7. Knee Osteoarthritis Treatment with the KineSpring Knee Implant System: A Report of Two Cases

    Directory of Open Access Journals (Sweden)

    David A. Hayes

    2012-01-01

    Full Text Available Osteoarthritis (OA is a leading cause of disability in middle-aged and older adults with the prevalence expected to increase by 40% by 2025. This dramatic projected increase in OA reflects, in large part, the alarming obesity epidemic. Indeed, it is now well understood that abnormal loading across the knee joint due to malalignment and/or excessive weight gain is responsible for accelerating OA progression. Consequently, there is a therapeutic need for alternative knee OA treatments that directly address joint overload to fill the gap between ineffective conservative care and invasive joint-modifying surgical procedures. We describe two cases that presented with bilateral knee OA resistant to conservative treatments, each with one knee previously and unsuccessfully treated with high tibial osteotomy to improve alignment and the contralateral knee successfully treated with a joint-preserving, load-absorbing implant (KineSpring Knee Implant System.

  8. Improvement in fetal DNA extraction from maternal plasma. Evaluation of the NucliSens Magnetic Extraction system and the QIAamp DSP Virus Kit in comparison with the QIAamp DNA Blood Mini Kit

    DEFF Research Database (Denmark)

    Clausen, Frederik Banch; Krog, Grethe Risum; Rieneck, Klaus

    2007-01-01

    Prenatal diagnostic assays have been developed using free fetal DNA circulating in the maternal blood of pregnant women. Efficient DNA extraction is crucial for a robust analysis. To improve fetal DNA yield, we tested two manual extraction methods--the NucliSens Magnetic Extraction (NMAG) system...... and the QIAamp DSP Virus Kit (QDSP)--against our current standard method, the widely used QIAamp DNA Blood Mini Kit (QDNA)....

  9. An Implanted Closed-loop Chip System for Heart Rate Control: System Design and Effects in Conscious Rats.

    Science.gov (United States)

    Zhou, Yuxuan; Yuan, Yuan; Gao, Juan; Yang, Ling; Zhang, Feng; Zhu, Guoqing; Gao, Xingya

    2010-03-01

    To evaluate the efficiency of an implanted chip system for the control of heart rate (HR). The HR was recorded in six conscious Sprague-Dawley (SD) rats. An implanted chip system was designed to regulate the HR by stimulating the right cervical vagus nerve according to the feedback of real time HR. Each rat was subjected to 30-min regulation and 30-min recovery. The change of HR during the regulation period was compared with the control. The ECG was recorded during the experiment for 24 h. The ECG signals were successfully recorded during the experiment. The HR was significantly decreased during the period of regulation compared with control (-79.3 ±34.5, P chip system can regulate the HR to a designated set point.

  10. Estudio de asociación entre enfermedades sistémicas y el fracaso de implantes dentales Study of association between systemic diseases and dental implant failure

    Directory of Open Access Journals (Sweden)

    J Domínguez

    2013-04-01

    , genero y el habito de fumar.Since the beginning of oral implant surgery it has been recommended to exclude or limit certain patients with health issues or smoking habits. The chronic non-communicable diseases are not considered an absolute contraindication to the use of oral implants, but the type of disease should be evaluated in detail, as a potential risk that could affect the process of osseointegration. There are certain systemic conditions, such as osteoporosis, cardiovascular disease, diabetes mellitus, and hypothyroidism, as well as the habit of smoking, that affect the success, survival or failure of the implants. The purpose of the investigation is to determine whether there is an association between the failure of dental implants and systemic diseases in the population of patients undergoing dental implant surgery of San José de Santiago de Chile Hospital. We conducted a retrospective observational study and the variables studied were systemic diseases (osteoporosis, hypertension, diabetes, and hypothyroidism and the criteria used to assess the health of implants were those of the International Congress of Oral Implantology of Pisa, where "failure" is the term used for implants requiring removal or that were already lost. These variables were recorded from the clinical record and during a clinical examination, in a data collection sheet. This allowed to describe variables and their distribution, and then to analyze the data to find statistically valid evidence. For this study we can conclude that the analysis of each of the variables such as systemic hypertension or ASA II, have an association with the failure of dental implants, but not osteoporosis, hypothyroidism, diabetes, age, nutritional status, gender and cigarette smoking.

  11. XIVE种植体即刻植入即刻负重的临床观察%Clinical Evaluation of XIVE Implants System in Immediate Implantation after Trauma

    Institute of Scientific and Technical Information of China (English)

    宣永华; 张卫群; 马泉生

    2011-01-01

    Objective: To investigate the clinical efficacy of XIVE implants system in immediate implantation, which in the traumatical maxillary anterior. Methods: A total of 26 patients were selected for the study, the fresh sockets were implanted with XIVE implants( torque ≥ 35 Ncm) system after the traumatically extraction of 32 teeth, and received immediate restoration at the same time. The final restora- tion were performed on average 4~5 months postoperatively. The clinical and radiography measures were used for 1, 2 and 4 months. Results: Among 32 implants, there were only 2 implants lost after operation, the others were good. Conclusion: The method of immediate implantation which take place in the traumatically area is feasible. This method can avoid bone tissue absorption,while remain soft and hard tissue mophorlogy, and reduce the period oftreatment.%目的:评价XIVE种植体在上颌外伤前牙区即刻种植即刻负重修复的临床效果.方法:对26例前牙区单颗或多颗无法保留的外伤残根拔除后,即刻植入 XIVE 种植体,并即刻负重修复.种植体扭矩控制在35Ncm 左右,初期稳定性良好.平均四到五个月后行永久修复.在植入后l、2、4 个月对其进行临床及影像学检查.结果:32枚种植体有2枚种植体2周后出现松动,一个月后脱落,其余30枚均在预期时间内形成良好骨性愈合,最终完成修复.结论:上颌前牙区单颗或多颗牙外伤,残根无法保留者,行即刻种植即刻负重修复是可行.早期种植修复有利于减缓牙槽骨的吸收,保留软硬组织的形态,缩短疗程.

  12. The Modern Mini-Computer in Laboratory Automation

    Science.gov (United States)

    Castellan, N. John, Jr.

    1975-01-01

    A report of the growth and present status of the mini-computer based, time sharing laboratory at the University of Indiana, which describes the system hardware, software, and applications in psychological experimentation. (EH)

  13. Materials directed to implants for repairing Central Nervous System

    Directory of Open Access Journals (Sweden)

    Canillas, M.

    2014-12-01

    Full Text Available Central Nervous System (CNS can be damaged by a wide range of injuries and disorders which entail permanent disability in some cases. Moreover, CNS repairing process presents some complications. The natural repair mechanism, which consists on the glial scar formation, is triggered by the inflammatory process. Molecules delivered during these processes, inflammation and glial scar formation as well as oxygen and glucose deficiencies due to the injury, create an inhibitory environment for axon regeneration and remyelination which is known as “secondary injury”. Biomaterials are taking up an even more important role in repairing CNS. Physicochemical properties of some ceramic materials have inspired different applications to repair CNS as substrates, electrodes or molecule vehicles. Based on their biocompatibility, capability to neutralize reactive species involved in the inflammatory processes and their versatile processing to obtain scaffolds with different shapes and sizes, ceramics are a succulent offer in nervous tissue engineering. Furthermore, their possibilities have been increased with polymeric-ceramics composites development, which have given rise to new interesting horizon.Existen diferentes tipos de lesiones o desordenes del Sistema Nervioso Central (SNC que pueden provocar graves secuelas e incluso en algunos casos una discapacidad permanente. Además, el proceso de reparación del SNC tiene algunas complicaciones. El mecanismo natural de reacción a una lesión, el cual consiste en la formación de una cicatriz glial, es desencadenado por un proceso inflamatorio. Las moléculas liberadas durante estos procesos, la inflamación y formación de la cicatriz glial, así como la deficiencia en oxígeno y glucosa debidos a la lesión, crean un ambiente que inhibe la regeneración axonal creando la llamada “lesión secundaria”. Los biomateriales están adquiriendo un papel cada vez más importante en la reparación de SNC. Las

  14. Impact of systemic diseases on oral health related quality of life after implant-prosthodontic rehabilitation

    Directory of Open Access Journals (Sweden)

    Tina Pretnar

    2014-08-01

    Full Text Available Background: Implant-prosthodontic rehabilitation improves oral health related quality of life (OHRQoL, but the presence of systemic diseases can also affect the well-being of an individual.The study was carried out to determine the relationship between systemic diseases and OHRQoL after implant-prosthodontic rehabilitation on the basis of psychometric testing by a standardized questionnaire »Oral Health Impact Profile« (OHIP.Methods: 130 patients, who received one to eight Ankylos® implants (on average 2.6 ± 1.8 were included in this retrospective study in which all aspects of the OHRQoL construct were evaluated with a Slovenian version of the OHIP questionnaire. Data on all present systemic diseases were obtained from the existing health records. Dental status and dental restorations were identified on the basis of orthopantomographic images.Results: The majority of subjects had a cardiovascular disease (N = 37; 28.5 %, followed by a headache (N = 15, 11.5 %, allergies and asthma (n = 13, 10 %, and a rheumatic disease (N = 11, 8.5 %. Only osteoporosis was statistically significantly related to OHRQoL after implant-prosthodontic rehabilitation (p = 0.024. The best multiple linear regression model for the summary score for the questionnaire »Oral Health Impact Profile« for Slovenia (OHIP, and taking into account gender and age as confounding factors, included the number of remaining teeth and the presence of osteoporosis (p = 0.003, adjusted R2 = 0.104.Conclusions: The total number of remaining teeth in the oral cavity (p = 0.031, the presence of osteoporosis (p = 0.024, and taking into account the subject’s gender and age, are the most important clinical factors that affect the functioning of the SGS as well as psychosocial behavior of the patients after an implant-prosthodontic rehabilitation (adjusted R2 = 0.104. Other systemic diseases (cardiovascular disease, headache, allergies and

  15. Remote monitoring of implantable cardioverter-defibrillators. Problems and implications using a telemonitoring system.

    Science.gov (United States)

    Siebermair, J; Clauss, S; Martens, E; Schuessler, F; Oversohl, N; Haserueck, N; Estner, H L; Kääb, S; Wakili, R

    2015-04-01

    The rising number of implantable devices has led to an increase in device-related workload, e.g., regular interrogation follow-up visits. Telemonitoring systems for implantable cardioverter-defibrillators (ICDs) seem to be a promising tool for reducing workload and costs, and they have the potential of optimizing patient care. However, issues such as practical functionality of ICD telemonitoring in daily routine may affect its broad implementation. The objective of this study was to evaluate potential problems during the implementation of a telemonitoring system, Medtronic CareLink™ (CL™) with respect to the installation and data transmission process. A total of 159 patients with ICDs who were equipped with the CL™ system were evaluated and followed up for 16 months regarding the success rate of the first data transmission via the telemonitoring system. In this cohort, a high rate of nontransmission of 23.9 % was observed after the 16-month follow-up. A detailed interview of these patients (no transmission) revealed that the main reasons for failed transmissions were due to the patients' loss of interest in the concept (approximately 50 %) as well as technical problems (approximately 25 %) with setting up the system. These results indicate that telemonitoring systems bear potential problems and that the evaluation of patient motivation and technical support options seems to play an important role in establishing the functionality of these systems.

  16. Comparison of SAGS I vs. SAGS II delivery systems in emerging implantation technologies

    Science.gov (United States)

    Despres, Joseph; Sweeney, Joseph

    2012-11-01

    The International Fire Code has classified Subatmospheric Gas Delivery Systems (SAGS) technologies into two main categories: SAGS Type I and SAGS Type II systems. SAGS Type I delivery systems both store and deliver gases at subatmospheric pressures. An example of this technology is ATMI's Safe Delivery Source (SDS®) adsorbent based cylinder. SAGS Type II delivery systems store fluids at high pressure and utilize mechanical devices internal to the cylinder to deliver the gas at subatmospheric pressures. Typical mechanical devices used to enable subatmospheric delivery are either set point regulators or mechanical capillary based systems. This paper focuses on how these delivery systems perform against the unique requirements of traditional beam line ion implantation as well as solar and flat panel applications. Specifically, data are provided showing the capability of these systems with respect to flow rate, residual gas left within the cylinder, and cylinder end-point flow and delivery pressure dynamics.

  17. Systemic Sclerosis and Silicone Breast Implant: A Case Report and Review of the Literature

    Directory of Open Access Journals (Sweden)

    Antonios Psarras

    2014-01-01

    Full Text Available Environmentally induced systemic sclerosis is a well-recognized condition, which is correlated with exposure to various chemical compounds or drugs. However, development of scleroderma-like disease after exposure to silicone has always been a controversial issue and, over time, it has triggered spirited debate whether there is a certain association or not. Herein, we report the case of a 35-year-old female who developed Raynaud’s phenomenon and, finally, systemic sclerosis shortly after silicone breast implantation surgery.

  18. Mini-DIAL system measurements coupled with multivariate data analysis to identify TIC and TIM simulants: preliminary absorption database analysis.

    Science.gov (United States)

    Gaudio, P.; Malizia, A.; Gelfusa, M.; Martinelli, E.; Di Natale, C.; Poggi, L. A.; Bellecci, C.

    2017-01-01

    Nowadays Toxic Industrial Components (TICs) and Toxic Industrial Materials (TIMs) are one of the most dangerous and diffuse vehicle of contamination in urban and industrial areas. The academic world together with the industrial and military one are working on innovative solutions to monitor the diffusion in atmosphere of such pollutants. In this phase the most common commercial sensors are based on “point detection” technology but it is clear that such instruments cannot satisfy the needs of the smart cities. The new challenge is developing stand-off systems to continuously monitor the atmosphere. Quantum Electronics and Plasma Physics (QEP) research group has a long experience in laser system development and has built two demonstrators based on DIAL (Differential Absorption of Light) technology could be able to identify chemical agents in atmosphere. In this work the authors will present one of those DIAL system, the miniaturized one, together with the preliminary results of an experimental campaign conducted on TICs and TIMs simulants in cell with aim of use the absorption database for the further atmospheric an analysis using the same DIAL system. The experimental results are analysed with standard multivariate data analysis technique as Principal Component Analysis (PCA) to develop a classification model aimed at identifying organic chemical compound in atmosphere. The preliminary results of absorption coefficients of some chemical compound are shown together pre PCA analysis.

  19. A wireless transmission system powered by an enzyme biofuel cell implanted in an orange.

    Science.gov (United States)

    MacVittie, Kevin; Conlon, Tyler; Katz, Evgeny

    2015-12-01

    A biofuel cell composed of catalytic electrodes made of "buckypaper" modified with PQQ-dependent glucose dehydrogenase and FAD-dependent fructose dehydrogenase on the anode and with laccase on the cathode was used to activate a wireless information transmission system. The cathode/anode pair was implanted in orange pulp extracting power from its content (glucose and fructose in the juice). The open circuit voltage, Voc, short circuit current density, jsc, and maximum power produced by the biofuel cell, Pmax, were found as ca. 0.6 V, ca. 0.33 mA·cm(-2) and 670 μW, respectively. The voltage produced by the biofuel cell was amplified with an energy harvesting circuit and applied to a wireless transmitter. The present study continues the research line where different implantable biofuel cells are used for the activation of electronic devices. The study emphasizes the biosensor and environmental monitoring applications of implantable biofuel cells harvesting power from natural sources, rather than their biomedical use.

  20. Implante con el sistema de reparación herniaria inguinal de prolene (Prolene hernia system

    Directory of Open Access Journals (Sweden)

    José Goderich Lalán

    2002-04-01

    Full Text Available Se realizó un estudio clinicodescriptivo y prospectivo del seguimiento de 21 pacientes a los que se les realizó implante sistema de reparación herniaria inguinal de prolene en hernias inguinales, reproducidas entre el 15 de octubre de 1998 y el 31 de marzo de 1999, con el objetivo de evaluar sus resultados. En todos los casos se utilizó el método de cirugía de corta estadía, anestesia local y sedación o espinal y antibioticoterapia profiláctica. En el seguimiento a muy corto plazo no se reportan recidivas y ninguna complicación posoperatoria. Más de la mitad de los pacientes había recibido más de 2 operaciones. La media de edad fue 49 años y el sexo predominante el masculino. La técnica que se utilizó para implante fue la recomendada por los fabricantesA clinical descriptive and prospective study of the follow-up of 21 patients who received implant of the Prolene inguinal hernia repair system in inguinal hernias reproduced between October l5th, 1998, and March 31st, 1999, was conducted aimed at evaluating the results. The short-stay surgery method, local anesthesia and sedation, or spinal anesthesia and prophylactic antibiotic therapy were used in all cases. No relapses or postoperative complications were reported in a very short-term follow-up. More than half of the patients had undergone more than 2 operations. Average age was 49 and there was a predominance of males. The technique used for the implant was the one recommended by the manufacturers

  1. 单片机在微型飞行器增稳系统中的应用%Applications of Single Chip Micyoco in Mini Air Vehicle's Stability Augmentation System

    Institute of Scientific and Technical Information of China (English)

    陈皓生; 李疆

    2001-01-01

    The stability augmentation system(SAS) is important in mini air vehicle's control system. Mini air vehicle's SAS should be small and light.The digital SAS can meet this request.The component of digital SAS are Single Chip Micyoco(SCM) and assistant circuit,but the most simple digital SAS can be realized by a single SCM.So it is very important to mini air vehicle's SAS design.%增稳系统在微型飞行器的控制系统中起到非常重要的作用。微型飞行器的增稳系统除了要实现增稳算法外,还要求系统的体积小、重量轻。数字式的增稳系统能很好地满足这些要求。数字式增稳系统的构成主要是单片机和外围电路,而最简单的数字控制系统可以只用一片单片机实现,这将极大地减小数字系统的体积和重量,而且便于增稳系统算法的选择和调试,对于微型飞行器的设计有极其重要的意义。

  2. First permanent human implant of the Stimulus Router System, a novel neuroprosthesis: preliminary testing of a polarity reversing stimulation technique.

    Science.gov (United States)

    Gan, Liu Shi; Ravid, Einat N; Kowalczewski, Jan; Gauthier, Michel; Olson, Jaret; Morhart, Michael; Prochazka, Arthur

    2011-01-01

    Neuroprostheses (NPs) are electrical stimulators that help to restore sensory or motor functions lost as a result of neural damage. The Stimulus Router System (SRS) is a new type of NP developed in our laboratory. The system uses fully implanted, passive leads to "capture" and "route" some of the current flowing between pairs of surface electrodes to the vicinity of the target nerves, hence eliminating the need for an implanted stimulator. In June 2008, 3 SRS leads were implanted in a tetraplegic man for restoration of grasp and release. To reduce the size of the external wristlet and thereby optimize usability, we recently implemented a polarity reversing stimulation technique that allowed us to eliminate a reference electrode. Selective activation of three target muscles was achieved by switching the polarities of the stimulus current delivered between pairs of surface electrodes located over the pick-up terminals of the implanted leads and reducing the amplitude of the secondary phases of the stimulus pulses.

  3. An implantable ENG detector with in-system velocity selective recording (VSR) capability.

    Science.gov (United States)

    Clarke, Chris; Rieger, Robert; Schuettler, Martin; Donaldson, Nick; Taylor, John

    2017-06-01

    Detection and classification of electroneurogram (ENG) signals in the peripheral nervous system can be achieved by velocity selective recording (VSR) using multi-electrode arrays. This paper describes an implantable VSR-based ENG recording system representing a significant development in the field since it is the first system of its type that can record naturally evoked ENG and be interfaced wirelessly using a low data rate transcutaneous link. The system consists of two CMOS ASICs one of which is placed close to the multi-electrode cuff array (MEC), whilst the other is mounted close to the wireless link. The digital ASIC provides the signal processing required to detect selectively ENG signals based on velocity. The design makes use of an original architecture that is suitable for implantation and reduces the required data rate for transmission to units placed outside the body. Complete measured electrical data from samples of the ASICs are presented that show that the system has the capability to record signals of amplitude as low as 0.5 μV, which is adequate for the recording of naturally evoked ENG. In addition, measurements of electrically evoked ENG from the explanted sciatic nerves of Xenopus Laevis frogs are presented.

  4. Sulfamethazine degradation in water by the VUV/UV process: Kinetics, mechanism and antibacterial activity determination based on a mini-fluidic VUV/UV photoreaction system.

    Science.gov (United States)

    Li, Mengkai; Wang, Chen; Yau, Miaoling; Bolton, James R; Qiang, Zhimin

    2017-01-01

    A mini-fluidic VUV/UV photoreaction system (MVPS) was developed in our previous study, and it was demonstrated as a powerful tool for studies on pollutant degradation by the VUV/UV process. In this study, we investigated the VUV/UV photodegradation of sulfamethazine (SMN), one of the most frequently detected antibiotics in the environment. The determination methods of photochemical kinetic parameters (e.g., photon fluence-based rate constant and quantum yield) were developed based on the MVPS. The photon fluence-based reaction rate constants for SMN degradation by UV alone and VUV/UV processes were determined as 0.07 × 10(3) and 4.11 × 10(3) m(2) einstein(-1), respectively, while their quantum yields were calculated as 0.019 and 0.369, respectively. The second-order reaction rate constant between hydroxyl radical (HO(•)) and SMN was determined to be 8.9 × 10(9) M(-1) s(-1) in VUV/UV irradiation experiments, which were conducted without addition of any other chemical. The pH effect on the SMN degradation by the VUV/UV process arose principally from SMN and HO speciation. In addition, six byproducts were identified and the potential degradation pathways of SMN including hydroxylation and SO2 elimination were proposed. The antibacterial activity of the SMN solution, assessed by the growth inhibition tests of Escherichia coli, decreased by about 80% after VUV/UV treatment up to a photon fluence of 3.58 × 10(-3) einstein m(-2). This study has developed methods for the determination of photochemical kinetic parameters using the newly developed MVPS and has demonstrated that the VUV/UV process is an effective technology to remove sulfonamide antibiotics in water.

  5. Experimental study on cyclosporine A drug delivery system in prevention of posterior capsule opacification after intraocular lens implantation in rabbits

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Objective To study the effect of cyclosporine A drug delivery system (CsA-DDS) on the prevention of posterior capsule opacification (PCO) after experimental intraocular lens implantation in rabbit eyes. Methods Twenty healthy New Zealand white rabbits, whose left eyes and right eyes were used respectively as experiment eyes and controls, were subjected to extracapsular lens extraction and artificial lens implantation. During the operation, CsA-DDS with poly (lactideco-glycolide) as carriers or empty DDS was...

  6. Extreme Agility Micro Aerial Vehicle - Control of Hovering Maneuvers for a Mini-Aerial Vehicle with an Onboard Autopilot System

    Science.gov (United States)

    2011-02-01

    montré que les commandes d’accélérateur ont compensé les effets des ailerons par une fonction d’anticipation, réduit l’erreur de tenue d’altitude à...expérimentales ont montré que les commandes d’accélérateur qui ont été compensées pour les effets des ailerons par une fonction d’anticipation, a réduit l’erreur...with a predictive error method found in the pro- cess identification tool from the Matlab system identification toolbox. A sampling time of 0.05 s was

  7. An Implantation and Detection System for Spectroscopy of 22,24Si

    Institute of Scientific and Technical Information of China (English)

    孙立杰; 马南茹; 王康; 臧宏亮; 王宏伟; 李琛; 施晨钟; 聂茂武; 李秀芳; 李贺; 马军兵; 徐新星; 马朋; 金仕纶; 黄美容; 白真; 王建国; 杨峰; 贾会明; 张焕乔; 刘祖华; 包鹏飞; 林承键; 王东玺; 吴振东; 杨彦云; 陈志强; 苏俊; 谌阳平; 周远杰; 马维虎; 陈杰; 王建松; 方德清; 李智焕; 王玉廷; 李晶; 杨磊

    2016-01-01

    A new decay detection system with high detection efficiency and low detection threshold has been developed for charged-particle decay studies, including β-delayed proton, α decay or direct proton emission from proton-rich nuclei. The detection system was tested by using theβ-delayed proton emitter 24Si and was commissioned in the decay study of 22Si produced by projectile fragmentation at the First Radioactive Ion Beam Line in Lanzhou. Under a continuous-beam mode, the isotopes of interest were implanted into two double-sided silicon strip detectors, where the subsequent decays were measured and correlated to the preceding implantations by using position and time information. The system allows to measure protons with energies down to about 200 keV without obvious β background in the proton spectrum. Further application of the detection system can be extended to the measurements ofβ-delayed proton decay and the direct proton emission of other exotic proton-rich nuclei.

  8. A Wireless Magnetic Resonance Energy Transfer System for Micro Implantable Medical Sensors

    Directory of Open Access Journals (Sweden)

    Tianyang Yang

    2012-07-01

    Full Text Available Based on the magnetic resonance coupling principle, in this paper a wireless energy transfer system is designed and implemented for the power supply of micro-implantable medical sensors. The entire system is composed of the in vitro part, including the energy transmitting circuit and resonant transmitter coils, and in vivo part, including the micro resonant receiver coils and signal shaping chip which includes the rectifier module and LDO voltage regulator module. Transmitter and receiver coils are wound by Litz wire, and the diameter of the receiver coils is just 1.9 cm. The energy transfer efficiency of the four-coil system is greatly improved compared to the conventional two-coil system. When the distance between the transmitter coils and the receiver coils is 1.5 cm, the transfer efficiency is 85% at the frequency of 742 kHz. The power transfer efficiency can be optimized by adding magnetic enhanced resonators. The receiving voltage signal is converted to a stable output voltage of 3.3 V and a current of 10 mA at the distance of 2 cm. In addition, the output current varies with changes in the distance. The whole implanted part is packaged with PDMS of excellent biocompatibility and the volume of it is about 1 cm3.

  9. MINI John Cooper Works Convertible

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    这辆名字巨长的迷你古巴其实和MINI CooperS没什么太大区别,最大的不同点就是MINI John Cooper Works Convertible采用软顶敞篷,而动力部分则是由John Cooper Works精心调校的那台1.6L排量双涡轮增压发动机.这台发动机与MINI Challenge赛车上使用的完全相同,拥有211hp和280Nm的动力输出。

  10. Cross-cultural adaptation and analysis of the psychometric properties of the Balance Evaluation Systems Test and MiniBESTest in the elderly and individuals with Parkinson's disease: application of the Rasch model

    Directory of Open Access Journals (Sweden)

    Angelica C. Maia

    2013-06-01

    Full Text Available BACKGROUND: Older adults and individuals with neurological problems such as Parkinson's disease (PD exhibit balance deficits that might impair their mobility and independence. The assessment of balance must be useful in identifying the presence of instability and orient interventions. OBJECTIVE: To translate and perform a cross-cultural adaptation of the Balance Evaluation Systems Test (BESTest and MiniBESTest to Brazilian Portuguese and analyze its psychometric properties. METHOD: The tests were translated and adapted to Portuguese according to a standard method and then subjected to a test-retest reliability assessment (10 older adults; 10 individuals with PD. The psychometric properties were assessed by the Rasch model (35 older adults; 35 individuals with PD. RESULTS: The reliability coefficient of the tests relative to the items and subjects varied from 0.91 and 0.98, which is indicative of the stability and reproducibility of the measures. In the BESTest, the person (4.19 and item (5.36 separation index established six balance ability levels and seven levels of difficulty, respectively. In the MiniBESTest, the person (3.16 and item (6.41 separation index established four balance ability levels and nine levels of difficulty, respectively. Two items in the BESTest did not fit with the model expectations, but the construct validity was not compromised. No item in the MiniBESTest was erratic. CONCLUSIONS: The results corroborate the diagnostic and screening functions of the BESTest and MiniBESTest, respectively, and indicate that the Brazilian versions exhibit adequate reliability, construct validity, response stability, and capacity to distinguish among various balance ability levels in older adults and individuals with PD.

  11. Virtual Reality in Health System: Beyond Entertainment. A Mini-Review on the Efficacy of VR During Cancer Treatment.

    Science.gov (United States)

    Chirico, Andrea; Lucidi, Fabio; De Laurentiis, Michele; Milanese, Carla; Napoli, Alessandro; Giordano, Antonio

    2016-02-01

    Virtual reality (VR), a computer-generated virtual environment, has been increasingly used in the entertainment world becoming a very new evolving field, but VR technology has also found a variety of applications in the biomedical field. VR can offer to subjects a safe environment within which to carry on different interventions ranging from the rehabilitation of discharged patients directly at home, to the support of hospitalized patients during different procedures and also of oncological inpatient subjects. VR appears as a promising tool for support and monitoring treatments in cancer patients influencing psychological and physiological functions. The aim of this systematic review is to provide an overview of all the studies that used VR intervention on cancer patients and analyze their main findings. Nineteen studies across nearly a thousand articles were identified that explored effects of VR interventions on cancer patients. Although these studies varied greatly in setting and design, this review identified some overarching themes. Results found that VR improved patients' emotional well-being, and diminished cancer-related psychological symptoms. The studies explored various relevant variables including different types of settings (i.e., during chemotherapy, during pain procedures, during hospitalization). Here, we point to the need of a global and multi-disciplinary approach aimed at analyzing the effects of VR taking advantage of the new technology systems like biosensors as well as electroencephalogram monitoring pre, during, and after intervention. Devoting more attention to bio-physiological variables, standardized procedures, extending duration to longitudinal studies and adjusting for motion sickness related to VR treatment need to become standard of this research field. © 2015 Wiley Periodicals, Inc.

  12. An implantable, designed-for-human-use peripheral nerve stimulation and recording system for advanced prosthetics.

    Science.gov (United States)

    Lachapelle, John R; Bjune, Caroline K; Kindle, Alexander L; Czarnecki, Andrew; Burns, John R; Grainger, Julianne E; Segura, Carlos A; Nugent, Brian D; Sriram, Tirunelveli S; Parks, Philip D; Keefer, Edward; Cheng, Jonathan

    2016-08-01

    Complex suture prostheses that deliver sensory and position feedback require a more sophisticated integration with the human user. Here a micro-size active implantable system that provides many-degree-of-freedom neural feedback in both sensory stimulation and motor control is shown, as one potential human-use solution in DARPA's HAPTIX program. Various electrical and mechanical challenge and solutions in meeting both sensory /motor performance as well as ISO 14708 FDA-acceptable human use in an aspirin-size active implementation are discussed.

  13. Superradiance by mini black holes with mirror

    OpenAIRE

    Lee, Jong-Phil

    2011-01-01

    The superradiant scattering of massive scalar particles by a rotating mini black hole is investigated. Imposing the mirror boundary condition, the system becomes the so called black-hole bomb where the rotation energy of the black hole is transferred to the scattered particle exponentially with time. Bulk emissions as well as brane emissions are considered altogether. It is found that the largest effects are expected for the brane emission of lower angular modes with lighter mass and larger a...

  14. Penile Implants

    Science.gov (United States)

    ... the discussion with your doctor. Types of penile implants There are two main types of penile implants: ... might help reduce the risk of infection. Comparing implant types When choosing which type of penile implant ...

  15. Functional brain fluorescence plurimetry in rat by implantable concatenated CMOS imaging system.

    Science.gov (United States)

    Kobayashi, Takuma; Masuda, Hiroyuki; Kitsumoto, Chikara; Haruta, Makito; Motoyama, Mayumi; Ohta, Yasumi; Noda, Toshihiko; Sasagawa, Kiyotaka; Tokuda, Takashi; Shiosaka, Sadao; Ohta, Jun

    2014-03-15

    Measurement of brain activity in multiple areas simultaneously by minimally invasive methods contributes to the study of neuroscience and development of brain machine interfaces. However, this requires compact wearable instruments that do not inhibit natural movements. Application of optical potentiometry with voltage-sensitive fluorescent dye using an implantable image sensor is also useful. However, the increasing number of leads required for the multiple wired sensors to measure larger domains inhibits natural behavior. For imaging broad areas by numerous sensors without excessive wiring, a web-like sensor that can wrap the brain was developed. Kaleidoscopic potentiometry is possible using the imaging system with concatenated sensors by changing the alignment of the sensors. This paper describes organization of the system, evaluation of the system by a fluorescence imaging, and finally, functional brain fluorescence plurimetry by the sensor. The recorded data in rat somatosensory cortex using the developed multiple-area imaging system compared well with electrophysiology results.

  16. Implantable Heart Aid

    Science.gov (United States)

    1984-01-01

    CPI's human-implantable automatic implantable defibrillator (AID) is a heart assist system, derived from NASA's space circuitry technology, that can prevent erratic heart action known as arrhythmias. Implanted AID, consisting of microcomputer power source and two electrodes for sensing heart activity, recognizes onset of ventricular fibrillation (VF) and delivers corrective electrical countershock to restore rhythmic heartbeat.

  17. Low-Gain, Low-Noise Integrated Neuronal Amplifier for Implantable Artifact-Reduction Recording System

    Directory of Open Access Journals (Sweden)

    Abdelhamid Benazzouz

    2013-09-01

    Full Text Available Brain neuroprostheses for neuromodulation are being designed to monitor the neural activity of the brain in the vicinity of the region being stimulated using a single macro-electrode. Using a single macro-electrode, recent neuromodulation studies show that recording systems with a low gain neuronal amplifier and successive amplifier stages can reduce or reject stimulation artifacts. These systems were made with off-the-shelf components that are not amendable for future implant design. A low-gain, low-noise integrated neuronal amplifier (NA with the capability of recording local field potentials (LFP and spike activity is presented. In vitro and in vivo characterizations of the tissue/electrode interface, with equivalent impedance as an electrical model for recording in the LFP band using macro-electrodes for rodents, contribute to the NA design constraints. The NA occupies 0.15 mm2 and dissipates 6.73 µW, and was fabricated using a 0.35 µm CMOS process. Test-bench validation indicates that the NA provides a mid-band gain of 20 dB and achieves a low input-referred noise of 4 µVRMS. Ability of the NA to perform spike recording in test-bench experiments is presented. Additionally, an awake and freely moving rodent setup was used to illustrate the integrated NA ability to record LFPs, paving the pathway for future implantable systems for neuromodulation.

  18. Mini-Membrane Evaporator for Contingency Spacesuit Cooling

    Science.gov (United States)

    Makinen, Janice V.; Bue, Grant C.; Campbell, Colin; Petty, Brian; Craft, Jesse; Lynch, William; Wilkes, Robert; Vogel, Matthew

    2015-01-01

    The next-generation Advanced Extravehicular Mobility Unit (AEMU) Portable Life Support System (PLSS) is integrating a number of new technologies to improve reliability and functionality. One of these improvements is the development of the Auxiliary Cooling Loop (ACL) for contingency crewmember cooling. The ACL is a completely redundant, independent cooling system that consists of a small evaporative cooler--the Mini Membrane Evaporator (Mini-ME), independent pump, independent feedwater assembly and independent Liquid Cooling Garment (LCG). The Mini-ME utilizes the same hollow fiber technology featured in the full-sized AEMU PLSS cooling device, the Spacesuit Water Membrane Evaporator (SWME), but Mini-ME occupies only approximately 25% of the volume of SWME, thereby providing only the necessary crewmember cooling in a contingency situation. The ACL provides a number of benefits when compared with the current EMU PLSS contingency cooling technology, which relies upon a Secondary Oxygen Vessel; contingency crewmember cooling can be provided for a longer period of time, more contingency situations can be accounted for, no reliance on a Secondary Oxygen Vessel (SOV) for contingency cooling--thereby allowing a reduction in SOV size and pressure, and the ACL can be recharged-allowing the AEMU PLSS to be reused, even after a contingency event. The first iteration of Mini-ME was developed and tested in-house. Mini-ME is currently packaged in AEMU PLSS 2.0, where it is being tested in environments and situations that are representative of potential future Extravehicular Activities (EVA's). The second iteration of Mini-ME, known as Mini-ME2, is currently being developed to offer more heat rejection capability. The development of this contingency evaporative cooling system will contribute to a more robust and comprehensive AEMU PLSS.

  19. Mini-Split Heat Pumps Multifamily Retrofit Feasibility Study

    Energy Technology Data Exchange (ETDEWEB)

    Dentz, J.; Podorson, D.; Varshney, K.

    2014-05-01

    Mini-split heat pumps can provide space heating and cooling in many climates and are relatively affordable. These and other features make them potentially suitable for retrofitting into multifamily buildings in cold climates to replace electric resistance heating or other outmoded heating systems. This report investigates the suitability of mini-split heat pumps for multifamily retrofits. Various technical and regulatory barriers are discussed and modeling was performed to compare long-term costs of substituting mini-splits for a variety of other heating and cooling options. A number of utility programs have retrofit mini-splits in both single family and multifamily residences. Two such multifamily programs are discussed in detail.

  20. Accuracy and precision of targeting using frameless stereotactic system in deep brain stimulator implantation surgery

    Directory of Open Access Journals (Sweden)

    Mayur Sharma

    2014-01-01

    Full Text Available Objectives: To assess the accuracy of targeting using NexFrame frameless targeting system during deep brain stimulation (DBS surgery. Materials and Methods: Fifty DBS leads were implanted in 33 patients using the NexFrame (Medtronic, Minneapolis, MN targeting system. Postoperative thin cut CT scans were used for lead localization. X, Y, Z coordinates of the tip of the lead were calculated and compared with the intended target coordinates to assess the targeting error. Comparative frame-based data set was obtained from randomly selected 33 patients during the same period that underwent 65 lead placements using Leksell stereotactic frame. Euclidean vector was calculated for directional error. Multivariate analysis of variance was used to compare the accuracy between two systems. Results: The mean error of targeting using frameless system in medio-lateral plane was 1.4 mm (SD ± 1.3, in antero-posterior plane was 0.9 mm (SD ± 1.0 and in supero-inferior plane Z was 1.0 mm (SD ± 0.9. The mean error of targeting using frame-based system in medio-lateral plane was 1.0 mm (SD ± 0.7, in antero-posterior plane was 0.9 mm (SD ± 0.5 and in supero-inferior plane Z was 0.7 mm (SD ± 0.6. The error in targeting was significantly more (P = 0.03 in the medio-lateral plane using the frameless system as compared to the frame-based system. Mean targeting error in the Euclidean directional vector using frameless system was 2.2 (SD ± 1.6 and using frame-based system was 1.7 (SD ± 0.6 (P = 0.07. There was significantly more error in the first 25 leads placed using the frameless system than the second 25 leads (P = 0.0015. Conclusion: The targeting accuracy of the frameless system was lower as compared to frame-based system in the medio-lateral direction. Standard deviations (SDs were higher using frameless system as compared to the frame-based system indicating lower accuracy of this system. Error in targeting should be considered while using frameless

  1. Evaluating the bending response of two osseointegrated transfemoral implant systems using 3D digital image correlation.

    Science.gov (United States)

    Thompson, Melanie L; Backman, David; Branemark, Rickard; Mechefske, Chris K

    2011-05-01

    Osseointegrated transfemoral implants have been introduced as a prosthetic solution for above knee amputees. They have shown great promise, providing an alternative for individuals who could not be accommodated by conventional, socket-based prostheses; however, the occurrence of device failures is of concern. In an effort to improve the strength and longevity of the device, a new design has been proposed. This study investigates the mechanical behavior of the new taper-based assembly in comparison to the current hex-based connection for osseointegrated transfemoral implant systems. This was done to better understand the behavior of components under loading, in order to optimize the assembly specifications and improve the useful life of the system. Digital image correlation was used to measure surface strains on two assemblies during static loading in bending. This provided a means to measure deformation over the entire sample and identify critical locations as the assembly was subjected to a series of loading conditions. It provided a means to determine the effects of tightening specifications and connection geometry on the material response and mechanical behavior of the assemblies. Both osseoinegrated assemblies exhibited improved strength and mechanical performance when tightened to a level beyond the current specified tightening torque of 12 N m. This was shown by decreased strain concentration values and improved distribution of tensile strain. Increased tightening torque provides an improved connection between components regardless of design, leading to increased torque retention, decreased peak tensile strain values, and a more gradual, primarily compressive distribution of strains throughout the assembly.

  2. A wirelessly controlled implantable LED system for deep brain optogenetic stimulation

    Directory of Open Access Journals (Sweden)

    Mark A. Rossi

    2015-02-01

    Full Text Available In recent years optogenetics has rapidly become an essential technique in neuroscience. Its temporal and spatial specificity, combined with efficacy in manipulating neuronal activity, are especially useful in studying the behavior of awake behaving animals. Conventional optogenetics, however, requires the use of lasers and optic fibers, which can place considerable restrictions on behavior. Here we combined a wirelessly controlled interface and small implantable light-emitting diode (LED that allows flexible and precise placement of light source to illuminate any brain area. We tested this wireless LED system in vivo, in transgenic mice expressing channelrhodopsin-2 in striatonigral neurons expressing D1-like dopamine receptors. In all mice tested, we were able to elicit movements reliably. The frequency of twitches induced by high power stimulation is proportional to the frequency of stimulation. At lower power, contraversive turning was observed. Moreover, the implanted LED remains effective over 50 days after surgery, demonstrating the long-term stability of the light source. Our results show that the wireless LED system can be used to manipulate neural activity chronically in behaving mice without impeding natural movements.

  3. Single-stage implantation in the atrophic alveolar ridge of the mandible with the Norian skeletal repair system.

    Science.gov (United States)

    Hölzle, Frank; Bauer, Florian; Kesting, Marco R; Mücke, Thomas; Deppe, Herbert; Wolff, Klaus-Dietrich; Swaid, Sami

    2011-10-01

    Dental implants have played a part in rehabilitation of the jaws for more than 40 years, but in some cases they alone are inadequate because of extreme alveolar resorption. Correction may necessitate a two-stage procedure with additional interventions. We have made a preliminary study of the use of the Norian skeletal repair system (SRS), a carbonated calcium phosphate bone cement used to augment the alveolar ridge as a single-stage procedure, with the placement of implants. Ten edentulous patients with insufficient vertical bone in the interforaminal area were treated. After a horizontal osteotomy and crestal mobilisation of the alveolar ridge, implants were placed through the crestal part and fixed in the basal part of the mandible. Norian SRS was used to fill the gap created. The prostheses were inserted 3 months later. Forty implants were inserted. The follow up period was 60 months, and no fractures or dislocations developed. One of the implants was lost and there was one wound dehiscence, but no surgical intervention or revision was necessary. Radiographs showed good consolidation of the bony structure in all cases. We have described a reliable, single-stage procedure for augmentation and implantation in a highly atrophic alveolar crest. A 98% survival is comparable with those of other techniques. Further clinical trials are necessary to replicate these promising results.

  4. Flux Emissions of SO2 and NO2 Measured at the Tula Industrial Complex (Mexico) during MCMA 2006 Field Campaign using a Mini-DOAS System

    Science.gov (United States)

    Sosa, G.; Rivera, C.; Wöhrnschimmel, H.; de Foy, B.; Johansson, M.; Molina, L. T.

    2007-05-01

    The Tula industrial zone is located 60 km northeast from the Mexico City Metropolitan Area (MCMA), in the Hidalgo State in México. This region is known as the Tula-Vito-Apasco industrial corridor, where a number of industries are located. According to the latest information from the environmental authority, about 313,000 ton/year of SO2 and 40,000 ton/year of NOx are released in this region. The Miguel Hidalgo refinery (MHR) and the Francisco Pérez Ríos power plant (FPRPP) are the main emitters, contributing almost 90% of SO2 and 80% of NOx from the total emission inside the Hidalgo State. Other industries such as cement plants, open-sky mines and agricultural activities are also responsible for important emissions of particulat matter (PM) into the atmosphere and soil erosion. This highly industrialized region is thought to influence the air quality in the MCMA, where in some occasions SO2 concentrations in the north part of the city have exceeded the Mexican air quality standard (130 ppb as a 24 hour average), which could not be attributed to irregular operations of industries located in the surrounding area. To address the question of emissions from the refinery and the power plant, the total fluxes of SO2 and NO2 were determined by measurements of their respective integrated vertical column in the neighborhood of the Tula industrial zone, using a Mini-DOAS system. These measurements were carried out as part of the MCMA-2006/MILAGRO Field Campaign, from March 24th to April 18th 2006. Meteorological measurements at the height of the plume dispersion were also determined using pilot balloons and radiosondes techniques. The experimental data were complemented by model simulations. Forward Lagrangian stochastic trajectories were calculated to simulate the plume using FLEXPART in combination with meso-scale meteorological simulations with MM5. The experimental data set was used to evaluate model performance. The simulations were used as an additional estimate of

  5. Clinical research on segmental invisible technique with mini-implant for en-masse retraction of maxillary anterior teeth%片段隐形矫治器结合微种植体内收上前牙的临床研究

    Institute of Scientific and Technical Information of China (English)

    金丽飞; 黄一慧; 弓国梁; 林新平

    2016-01-01

    Objective To evaluate the clinical efficiency of segmental invisible technique with mini-implant for en-masse retraction of maxillary anterior teeth on the aspect of vertical and torque in the treatment of bimaxillary protrusion. Methods Twelve subjects with upper dental alveolar bone protrusion were selected for this study. Arch-dimension variables were evaluated by cephalometric and dental models before and after orthodontic retraction. All data were analyzed by SPSS 20. 0 software. Results For vertical control, U1E-PP was increased by 0. 78 mm, U1AP-PP was decreased by 0. 29 mm, while the change of U1CR-PP showed no significant difference ( P>0. 05). For sagittal control, all the anterior teeth showed a decreased torque with canine displaying uprighting. Conclusion Segmen-tal invisible technique with mini-implant is efficient in the vertical and torque control of anterior teeth in the treatment of bimaxillary protrusion, and it can demonstrate invisible and aesthetic orthodontic effects.%目的:评估片段隐形矫治器结合微种植体矫治前突患者时对上前牙垂直向和转矩方面的控制效果。方法选取12例双牙槽前突患者,通过测量治疗前后X线头颅定位侧位片上颌前牙矢状向与垂直向的变化值,以及模型上的转矩变化值,使用SPSS 20.0软件进行统计分析。结果治疗后上切牙切缘至腭平面距离U1E-PP增加0.78 mm,上切牙根尖点至腭平面距离U1AP-PP减小0.29 mm,上切牙阻抗中心至腭平面距离U1CR-PP的变化无统计学差异(P>0.05),上切牙阻抗中心的位置基本不变;治疗后的上前牙转矩值减少,尖牙出现直立趋势。结论片段隐形矫治技术治疗前突患者对其上前牙的垂直向和转矩控制较好,总体获得了良好的治疗效果,并且在治疗期间充分发挥了隐形、美观的矫治效果。

  6. Calibration of {sup 90}Sr+{sup 90}Y chemical applicators using a mini extrapolation chamber as reference system;Calibracao de aplicadores clinicos de {sup 90}Sr+{sup 90}Y utilizando uma mini-camera de extrapolacao como sistema de referencia

    Energy Technology Data Exchange (ETDEWEB)

    Antonio, Patricia L.; Caldas, Linda V.E. [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil); Oliveira, Mercia L. [Centro Regional de Ciencias Nucleares do Nordeste (CRCN-NE/CNEN-PE), Recife, PE (Brazil)

    2009-07-01

    {sup 90}Sr + {sup 90}Y clinical applicators are beta radiation sources utilized in several radiotherapy Brazilian clinics, although don't be more manufactured. These sources are employed in brachytherapy procedures for the treatment of superficial lesions of skin and eyes. International recommendations and previous works determine that dermatological and ophthalmic applicators shall be calibrated periodically, and one of the methods for their calibration consists of the use of an extrapolation chamber. In this work, a method of calibration of {sup 90}Sr + {sup 90}Y clinical applicators was applied using a mini-extrapolation chamber of plane window, developed at the Calibration Laboratory at IPEN, as a reference system. The results obtained were considered satisfactory, when compared with the results given in the calibration certificates of the sources. (author)

  7. Testing the retention of attachments for implant overdentures - validation of an original force measurement system.

    Science.gov (United States)

    Fromentin, O; Lassauzay, C; Abi Nader, S; Feine, J; de Albuquerque Junior, R F

    2010-01-01

    The aim of this study was to validate an original portable device to measure attachment retention of implant overdentures both in the lab and in clinical settings. The device was built with a digital force measurement gauge (Imada) secured to a vertical wheel stand associated with a customized support to hold and position the denture in adjustable angulations. Sixteen matrix and patrix cylindrical stud attachments (Locator) were randomly assigned as in vitro test specimens. Attachment abutments were secured in an implant analogue hung to the digital force gauge or to the load cell of a traction machine used as the gold standard (Instron Universal Testing Machine). Matrices were secured in a denture duplicate attached to the customized support, permitting reproducibility of their position on both pulling devices. Attachment retention in the axial direction was evaluated by measuring maximum dislodging force or peak load during five consecutive linear dislodgments of each attachment on both devices. After a wear simulation, retention was measured again at several time periods. The peak load measurements with the customized Imada device were similar to those obtained with the gold standard Instron machine. These findings suggest that the proposed portable device can provide accurate information on the retentive properties of attachment systems for removable dental prostheses.

  8. Longitudinal hemodynamic measurements in swine heart failure using a fully implantable telemetry system.

    Directory of Open Access Journals (Sweden)

    Jenny S Choy

    Full Text Available Chronic monitoring of heart rate, blood pressure, and flow in conscious free-roaming large animals can offer considerable opportunity to understand the progression of cardiovascular diseases and can test new diagnostics and therapeutics. The objective of this study was to demonstrate the feasibility of chronic, simultaneous measurement of several hemodynamic parameters (left ventricular pressure, systemic pressure, blood flow velocity, and heart rate using a totally implantable multichannel telemetry system in swine heart failure models. Two solid-state blood pressure sensors were inserted in the left ventricle and the descending aorta for pressure measurements. Two Doppler probes were placed around the left anterior descending (LAD and the brachiocephalic arteries for blood flow velocity measurements. Electrocardiographic (ECG electrodes were attached to the surface of the left ventricle to monitor heart rate. The telemeter body was implanted in the right side of the abdomen under the skin for approximately 4 to 6 weeks. The animals were subjected to various heart failure models, including volume overload (A-V fistula, n = 3, pressure overload (aortic banding, n = 2 and dilated cardiomyopathy (pacing-induced tachycardia, n = 3. Longitudinal changes in hemodynamics were monitored during the progression of the disease. In the pacing-induced tachycardia animals, the systemic blood pressure progressively decreased within the first 2 weeks and returned to baseline levels thereafter. In the aortic banding animals, the pressure progressively increased during the development of the disease. The pressure in the A-V fistula animals only showed a small increase during the first week and remained stable thereafter. The results demonstrated the ability of this telemetry system of long-term, simultaneous monitoring of blood flow, pressure and heart rate in heart failure models, which may offer significant utility for understanding cardiovascular disease

  9. A mini-UAV VTOL Platform for Surveying Applications

    Directory of Open Access Journals (Sweden)

    Kuldeep Rawat

    2014-05-01

    Full Text Available In this paper we discuss implementation of a mini-Unmanned Aerial Vehicle (UAV vertical take-off and landing (VTOL platform for surveying activities related to highway construction. Recent advances in sensor and communication technologies have allowed scaling sizes of unmanned aerial platforms, and explore them for tasks that are economical and safe over populated or inhabited areas. In highway construction the capability of mini-UAVs to survey in hostile and/or hardly accessible areas can greatly reduce human risks. The project focused on developing a cost effective, remotely controlled, fuel powered mini-UAV VTOL (helicopter platform with certain payload capacity and configuration and demonstrated its use in surveying and monitoring activities required for highway planning and construction. With an on-board flight recorder global positioning system (GPS device, memory storage card, telemetry, inertial navigation sensors, and a video camera the mini-UAV can record flying coordinates and relay live video images to a remote ground receiver and surveyor. After all necessary integration and flight tests were done the mini-UAV helicopter was tested to operate and relay video from the areas where construction was underway. The mini-UAV can provide a platform for a range of sensors and instruments that directly support the operational requirements of transportation sector.

  10. Spurious RF signals emitted by mini-UAVs

    Science.gov (United States)

    Schleijpen, Ric (H. M. A.); Voogt, Vincent; Zwamborn, Peter; van den Oever, Jaap

    2016-10-01

    This paper presents experimental work on the detection of spurious RF emissions of mini Unmanned Aerial Vehicles (mini-UAV). Many recent events have shown that mini-UAVs can be considered as a potential threat for civil security. For this reason the detection of mini-UAVs has become of interest to the sensor community. The detection, classification and identification chain can take advantage of different sensor technologies. Apart from the signatures used by radar and electro-optical sensor systems, the UAV also emits RF signals. These RF signatures can be split in intentional signals for communication with the operator and un-intentional RF signals emitted by the UAV. These unintentional or spurious RF emissions are very weak but could be used to discriminate potential UAV detections from false alarms. The goal of this research was to assess the potential of exploiting spurious emissions in the classification and identification chain of mini-UAVs. It was already known that spurious signals are very weak, but the focus was on the question whether the emission pattern could be correlated to the behaviour of the UAV. In this paper experimental examples of spurious RF emission for different types of mini-UAVs and their correlation with the electronic circuits in the UAVs will be shown

  11. Use of Implantable Venous Port Systems in the Treatment of Children with Orphan Diseases (Mucopolysaccharidosis and Pompe Disease: Case Series

    Directory of Open Access Journals (Sweden)

    M. Yu. Rykov

    2015-01-01

    Full Text Available Many orphan diseases in children require life-long and regular intravenous enzyme replacement therapy. The article describes the first Russian practice of implanting venous port systems in 12 patients with type I and II mucopolysaccharidosis and Pompe disease (6 months to 17 years old to create long-term venous access. Currently, implantable venous port systems are used in 9 (75% of 12 patients. 4 cases of thrombosis are observed in 3 patients. All of them have been successfully treated. 1 patient had a rotation of the port camera with a membrane facing downwards due to violation of an implantation technique. The camera was adjusted during the second operation.

  12. Fixed Implant Supported Rehabilitation of Partially Edentulous Posterior Maxilla in a Patient With Systemic Scleroderma: A Case Report.

    Science.gov (United States)

    Baptist, Benjamin A

    2016-02-01

    Systemic Scleroderma (SSc) is an autoimmune disease that affects connective tissue, resulting in hardening skin, reduced vascular perfusion, gingival fibrosis, enlarged periodontal ligament, xerostomia, and trigeminal neuralgia. Secondary effects, including reduced oral opening and reduced manual dexterity may exacerbate the primary effects. Severe bone loss and premature tooth loss are common eventualities of SSc. Removable prosthetics can be a tedious option for these patients as the progression of the disease often leads to the impossibility of obtaining minimal standards of care, including stability, retention, and hygienic maintainability. Implant treatment of patients with Systemic Scleroderma is poorly documented, and common medications used to treat SSc have been considered relative contraindications to the prescription of dental implant therapy. This report describes 1 case after 2 years in function, where dental implants were successfully utilized to offer definitive fixed rehabilitation to a patient with SSc.

  13. Electroanalysis of tetracycline using nickel-implanted boron-doped diamond thin film electrode applied to flow injection system.

    Science.gov (United States)

    Treetepvijit, Surudee; Chuanuwatanakul, Suchada; Einaga, Yasuaki; Sato, Rika; Chailapakult, Orawon

    2005-05-01

    The electrochemical analysis of tetracycline was investigated using nickel-implanted boron-doped diamond thin film electrode by cyclic voltammetry and amperometry with a flow injection system. Cyclic voltammetry was used to study the electrochemical oxidation of tetracycline. Comparison experiments were carried out using as-deposited boron-doped diamond thin film electrode (BDD). Nickel-implanted boron-doped diamond thin film electrode (Ni-DIA) provided well-resolved oxidation irreversible cyclic voltammograms. The current signals were higher than those obtained using the as-deposited BDD electrode. Results using nickel-implanted boron-doped diamond thin film electrode in flow injection system coupled with amperometric detection are presented. The optimum potential for tetracycline was 1.55 V versus Ag/AgCl. The linear range of 1.0 to 100 microM and the detection limit of 10 nM were obtained. In addition, the application for drug formulation was also investigated.

  14. THE RESULTS OF MECHANICAL HEART SUPPORT SYSTEMS «INCOR» IMPLANTATION

    Directory of Open Access Journals (Sweden)

    A. M. Cherniavskiy

    2013-01-01

    Full Text Available The aim of investigation isestimation of mechanical heart support system «INCOR» implantation efficacy. Materials and methods. The Institute of Circulation Pathology has clinical experience of mechanical circulatory support systems «INCOR» (Berlin Heart AG implantation in 12 patients (10 men and 2 women with severe heart failure during the period from November 2006 to October 2012. The main indication for the use of mechanical support of the left ventricle was a left ventricular failure with marked dilatation of the left heart: end-diastolic volume (EDV, LV – 283 ± 58 ml, end-systolic volume (ESV – 233 ± 57 ml, ejection fraction (EF – 16 ± 7%, with preserved function of the right ventricle (RV (RV ejection fraction 35 ± 12%. Results. All patients showed a significant improvement in central hemodynamics in early postoperative period, reducing the volume of the heart chambers: LV EDV from 283 ± 58 to 183 ± 94 ml; LV ESV with 234 ± 57 to 157 ± 65 ml, increased right ventricular ejection fraction (RV EF (from 35 ± 12 to 43 ± 17%. Improve the function of the right ventricle oc- curred mainly due to the expense of left ventricular unloading and pulmonary circulation. In addition, there was a significant improvement in clinical status of patients – regression of symptoms of heart failure, a recovery of the liver and kidney function. Despite the ongoing anticoagulation and antiplatelet therapy under constant parameters of coagulation, there was some complications. Uterine bleeding occurred in 1 patient (16.6%, which required the abolition of anticoagulants and antiplatelet, uterine artery embolization, and as a result has led to thrombosis and stop system «INCOR». Four patients (33.3% had severe thromboembolic complications – acute cerebrovascular accident (CVA. In 1 patient (8% there was a hemorrhagic stroke due to rupture of intracerebral aneurysms with a breakthrough into the lateral ventricle of the brain. In 3 patients (25

  15. A comparative evaluation of implant supported zirconia framework gap of two CAD/CAM systems

    Directory of Open Access Journals (Sweden)

    Narges Ameri

    2016-11-01

    computer-aided manufacturing (CAM systems (AmannGirrbach and Zirkonzahn. Materials and Methods: The master model of 3-unit FDP was made of two implant abutments (AmannGirrbach and Zirkonzahn from canine to second premolar. Twelve frameworks were manufactured using each fabricating system from semi-sintered zirconia blanks, which had to be sintered for final density after milling. After manufacturing, the absolute marginal discrepancy in each abutment were determined by means of Video Measurement System (VMS. The data were analyzed, using independent and paired t test (P=0.05. Results: For the premolar abutment, the absolute marginal discrepancy of frameworks fabricated by AmannGirrbach system was significantly greater than those of the other system (P=0.005. There was no significant difference between the marginal discrepancy of canine and premolar abutments (P>0.05. Conclusion: Within the limitations of this study, it could be concluded that the marginal fit of zirconia FDPs was significantly dependent on the CAD/CAM system used, but the abutment size was not an effective factor.

  16. Design and optimization of a 3-coil resonance-based wireless power transfer system for biomedical implants

    KAUST Repository

    Yi, Ying

    2014-09-01

    This paper presents a resonance-based wireless power transfer system using a single layer of inductor coil windings, in a pancake configuration, in order to obtain a compact system for implantable electronic applications. We theoretically analyzed the system and characterized it by measuring its inductance, self-resonant frequency, and quality factor Q. In our resonance-based wireless power transfer prototype, we proposed a 3-coil system, using two 15-mm radius implantable coils, with a resonance frequency of 6.76MHz. This system can effectively transfer power for a distance of up to 50mm. Moreover, our proposed 3-coil system can achieve a high Q-factor and has a comparable power transfer efficiency (PTE) to previously reported works about 3-coil and 4-coil systems. The experimental PTE can achieve 82.4% at a separation distance of 20mm and more than 10% PTE at a distance of 40mm.

  17. Reconstitution of the central nervous system during salamander tail regeneration from the implanted neurospheres.

    Science.gov (United States)

    McHedlishvili, Levan; Mazurov, Vladimir; Tanaka, Elly M

    2012-01-01

    Urodele amphibians such as axolotl are well known for their regenerative potential of the damaged central nervous system structures. Upon tail amputation, neural stem cells behind the amputation plane undergo self-renewing divisions and contribute to the functional spinal cord in the newly formed regenerate. The neural stem cells, harboring this potential, can be isolated from the animal and cultured under the suspension conditions. After 2-3 weeks in vitro they will proliferate and form the floating aggregates of the spherical shape, so-called neurospheres. Reimplanted back into the animal, the neurospheres can efficiently integrate in the spinal cord lesion and contribute to the following spinal cord regeneration events. Here we demonstrate the unique method of the axolotl tail spinal cord regeneration from the implanted neurosphere.

  18. Mandibular two-implant overdentures: three-year prosthodontic maintenance using the locator attachment system.

    Science.gov (United States)

    Mackie, Andrew; Lyons, Karl; Thomson, W Murray; Payne, Alan G T

    2011-01-01

    Limited clinical research identifies prosthodontic maintenance requirements of mandibular overdentures using the Locator attachment system. Sixty-five edentulous participants received complete maxillary dentures opposing mandibular two-implant overdentures with either Locator nylon (n = 21), Southern plastic (n = 24), or Straumann gold (n = 20) matrices. Prosthodontic maintenance was recorded prospectively for 3 years using defined categories. Over the 3-year period, a mean 3.52 ± 4.8, 2.08 ± 1.9, and 5.5 ± 4.2 maintenance events occurred for Locator, Southern, and Straumann participants, respectively. Prosthodontic success rates of 90% in the Locator nylon group, 88% in the Southern plastic group, and 75% in the Straumann gold group were achieved. Int J Prosthodont 2011;24:328-331.

  19. A comparative analysis of the accuracy of implant transfer impressions using the Ankylos® system

    OpenAIRE

    Haubold, Henrik

    2010-01-01

    A follow-up long term prognosis of an implant retained superstructure depends heavily in an exact and precise fitting. In order to achieve this precise fitting the impression must ?register? the exact position of the implants in the oral cavity. This procedure seems to be the critical factor for the fitting precision of the implantsupported superstructure. The objective of this study was measuring the influence of different parameters to transfer precision of implant positions using the...

  20. Surviving the Consolidation Crunch through the Use of a Mini Computer.

    Science.gov (United States)

    Clark, Donald W.

    1978-01-01

    Consolidation of Central Washington University's computing capability to an off-campus state service center and the use of mini computers on campus is discussed. The mini computer system is cost effective and provides an efficient on-line interactive student information system for the small and medium size institution. (BH)

  1. Functional biocompatibility testing of silicone breast implants and a novel classification system based on surface roughness.

    Science.gov (United States)

    Barr, S; Hill, E W; Bayat, A

    2017-06-27

    Increasing numbers of women undergo breast implantation for cosmetic and reconstructive purposes. Contracture of the fibrous capsule, which encases the implant leads to significant pain and reoperation. Texture, wettability and the cellular reaction to implant surfaces are poorly understood determinants of implant biocompatibility. The aim of this study was to evaluate the in-vitro characteristics of a range of commercial available implants using a macrophage based assay of implant biocompatibility and a quantitative assessment of wettability and texture. Thirteen commercially available surfaces were subjected to wettability and texture characterisation using scanning and laser confocal microscopy. THP-1 macrophages were cultured on their surfaces and assessed using Integrin αV immunocytochemistry, SEM and RT-PCR for the expression of TNF-Alpha, IL-6, IL-10 and a cytokine array for the production of TNF-alpha, IL-10, IL-1RA and IL1β; important indicators of inflammation and macrophage polarization. Textured surfaces can be accurately sub-categorized dependent upon roughness and re-entrant features into four main types (macro, micro, meso and nano-textured surfaces). Significant (P based on roughness and present a macrophage based assay of breast implant biocompatibility with a quantitative assessment of implant wettability and texture. The breast implant surface-cell interaction is variable and sufficient to alter healing response and capsular contracture fate in-vivo. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

  2. Implant overdenture using a locator bar system by drill and tapping technique in a mandible edentulous patient: a case report.

    Science.gov (United States)

    Kim, Min-Su; Yoon, Mi-Jung; Huh, Jung-Bo; Jeon, Young-Chan; Jeong, Chang-Mo

    2012-05-01

    Various options have been introduced for the selection of implant overdenture attachments. Attachment wear due to the repeated insertion and removal of dentures has caused problems such as decreased retention and the requirement for suprastructure remanufacturing. In these cases, a Locator bar system was applied using the drill and tapping technique to achieve total retrievability. In a 55-year-old female patient who showed three degrees of mobility in most of her teeth due to severe alveolar bone loss, a complete denture in the maxilla and an implant supported type overdenture in the mandible were planned after extracting all the remaining teeth. Six implants were placed from canine region to the distal molar region, and the locator was connected to the milled bar using the drill and tapping technique. For a 61-year-old female edentulous patient who complained of poor retention with old denture, a complete denture in the maxilla and an implant-tissue supported type overdenture in the mandible were planned. Four implants were placed in front of mental foramen, and the Locator was also connected to the Hader bar using the drill and tapping technique. With this technique, female parts can be easily replaced, and retention can be continuously maintained.

  3. [Mandibular bone tissue regeneration after the introduction of the implantation system performed on the basis of carbon composite material].

    Science.gov (United States)

    Chetvertnykh, V A; Loginova, N P; Astashina, N B; Rogozhnikov, G I; Rapekta, S I

    2013-01-01

    The purpose of this study was to investigate the processes of regeneration of bone tissue after the introduction of new implant systems. In the experiment, performed on 10 male pigs of Landras breed aged 50-55 days and weighing 17-18.5 kg, the time course of histological changes was studied in the area of mandibular regeneration after the formation of tissue defect and the introduction of the implant of a proposed construction. Morphological analysis of the experimental results 90, 180 and 270 days after the operation demonstrated the process of reparative regeneration of damaged bone along implant-bone block boundaries. Bone repair proceeded through the stage of formation of the woven bone with its progressive substitution by the lamellar bone, with the maintenance of the shape, size and symmetry of the damaged organ.

  4. Otimização do tratamento ortodôntico utilizando o Centrex System para retração dos dentes anteriores

    OpenAIRE

    José Kleber Soares de Meireles; Weber Ursi

    2012-01-01

    INTRODUCTION: In the end of 90's the adoption of mini-implants as Anchorage allowed a paradigm change influencing even the way of thinking orthodontic mechanics. The overlapping of the specialties of Orthodontics and Implantology started with orthodontic preparations for prosthetic implants insertion, aroused with the use of palatal implants and late with the introduction of mini-implants. The improvement of mini-implants insertion technique with the appearing of self-drilling screws has allo...

  5. Dental Implants.

    Science.gov (United States)

    Griggs, Jason A

    2017-10-01

    Systematic reviews of literature over the period between 2008 and 2017 are discussed regarding clinical evidence for the factors affecting survival and failure of dental implants. The factors addressed include publication bias, tooth location, insertion torque, collar design, implant-abutment connection design, implant length, implant width, bone augmentation, platform switching, surface roughness, implant coatings, and the use of ceramic materials in the implant body and abutment. Copyright © 2017 Elsevier Inc. All rights reserved.

  6. Estudio del espesor de la mucosa del trígono retromolar con el objetivo de facilitar la planificación de mini implantes en la región

    OpenAIRE

    Alves, Nilton [UNESP; Nascimento, Carlos Manuel de Oliveira

    2012-01-01

    The retromolar triangle is a triangular area located in the mandible, posteriorly to the last molar. This region, due its thickness and bone density, is widely used for the installation of devices that provide an anchorage system for the movement of the lower molars. The aim of this research is to provide morphometric data of the mucosa thickness of the retromolar triangle. Twenty-five patients of portuguese nationality, with indication for extraction of the impacted lower third molar (right ...

  7. Low-Power, 8-Channel EEG Recorder and Seizure Detector ASIC for a Subdermal Implantable System.

    Science.gov (United States)

    Do Valle, Bruno G; Cash, Sydney S; Sodini, Charles G

    2016-12-01

    EEG remains the mainstay test for the diagnosis and treatment of patients with epilepsy. Unfortunately, ambulatory EEG systems are far from ideal for patients who have infrequent seizures. These systems only last up to 3 days and if a seizure is not captured during the recordings, a definite diagnosis of the patient's condition cannot be given. This work aims to address this need by proposing a subdermal implantable, eight-channel EEG recorder and seizure detector that has two modes of operation: diagnosis and seizure counting. In the diagnosis mode, EEG is continuously recorded until a number of seizures are recorded. In the seizure counting mode, the system uses a low-power algorithm to track the number of seizures a patient has, providing doctors with a reliable count to help determine medication efficacy or other clinical endpoint. An ASIC that implements the EEG recording and seizure detection algorithm was designed and fabricated in a 0.18 μm CMOS process. The ASIC includes eight EEG channels and is designed to minimize the system's power and size. The result is a power-efficient analog front end that requires 2.75 μW per channel in diagnosis mode and 0.84 μW per channel in seizure counting mode. Both modes have an input referred noise of approximately 1.1 μVrms.

  8. Sustained systemic delivery of green tea polyphenols by polymeric implants significantly diminishes benzo[a]pyrene-induced DNA adducts.

    Science.gov (United States)

    Cao, Pengxiao; Vadhanam, Manicka V; Spencer, Wendy A; Cai, Jian; Gupta, Ramesh C

    2011-06-20

    The polyphenolics in green tea are believed to be the bioactive components. However, poor bioavailability following ingestion limits their efficacy in vivo. In this study, polyphenon E (poly E), a standardized green tea extract, was administered by sustained-release polycaprolactone implants (two, 2-cm implants; 20% drug load) grafted subcutaneously or via drinking water (0.8% w/v) to female S/D rats. Animals were treated with continuous low dose of benzo[a]pyrene (BP) via subcutaneous polymeric implants (2 cm; 10% load) and euthanized after 1 and 4 weeks. Analysis of lung DNA by (32)P-postlabeling resulted in a statistically significant reduction (50%; p = 0.023) of BP-induced DNA adducts in the implant group; however, only a modest (34%) but statistically insignificant reduction occurred in the drinking water group at 1 week. The implant delivery system also showed significant reduction (35%; p = 0.044) of the known BP diolepoxide-derived DNA adduct after 4 weeks. Notably, the total dose of poly E administered was >100-fold lower in the implant group than the drinking water group (15.7 versus 1,632 mg, respectively). Analysis of selected phase I, phase II, and nucleotide excision repair enzymes at both mRNA and protein levels showed no significant modulation by poly E, suggesting that the reduction in the BP-induced DNA adducts occurred presumably due to known scavenging of the antidiolepoxide of BP by the poly E catechins. In conclusion, our study demonstrated that sustained systemic delivery of poly E significantly reduced BP-induced DNA adducts in spite of its poor bioavailability following oral administration.

  9. The impact of glucocorticosteroids administered for systemic diseases on the osseointegration and survival of dental implants placed without bone grafting-A retrospective study in 31 patients.

    Science.gov (United States)

    Petsinis, Vassilis; Kamperos, Georgios; Alexandridi, Foteini; Alexandridis, Konstantinos

    2017-08-01

    To evaluate the impact of glucocorticosteroids, administered for the treatment of systemic diseases, on the osseointegration and survival of dental implants placed without bone grafting. A retrospective study was conducted in search of patients treated with dental implants while receiving glucocorticosteroid therapy for various systemic diseases. In these cases, a conventional two-stage surgical protocol was used, without bone regeneration procedures. The osseointegration was clinically and radiographically tested at the uncovering of the implants. The follow-up after loading was set at a minimum of 3 years. A total of 31 patients were included in the study. Of the 105 dental implants placed, 104 were osseointegrated (99%). No bone absorption was radiographically noted at the uncovering of the osseointegrated implants. All of the osseointegrated implants were successfully loaded for the prosthetic restoration. The mean follow-up period after loading was 71 months, with an implant survival rate of 99%. Glucocorticosteroid intake for systemic diseases does not have a significant impact on the osseointegration and the 3-year survival of dental implants placed with a conventional two-stage surgical protocol and without bone grafting. Therefore, it should not be considered a contraindication for dental implant placement. Copyright © 2017 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.

  10. Development of an 8 miniSTR and Amelogenin fluorescent-multiplex system%荧光标记8个miniSTR及Amelogenin复合扩增体系的建立

    Institute of Scientific and Technical Information of China (English)

    刘超; 冯冬亮; 刘长晖

    2011-01-01

    目的 建立非CODIS系统miniSTR以及Amelogenin基因座的荧光复合扩增体系.方法 筛选8个多态性高的非CODIS系统miniSTR基因座(D20S1082、D6S474、D12ATA63、D9S1122、D2S1776、D1S1627、D3S4529、D2S441),并结合Amelogenin基因座设计荧光标记引物,优化反应条件,建立复合扩增体系.应用该体系对204份广州地区汉族血样,30个家系样本,及30份降解检材进行检测.结果 建立的荧光标记8个miniSTR及Amelogenin复合扩增体系分型结果明确,稳定性好,且所有片段长度均少于200bp,提高了降解检材的分型成功率.在广州汉族人群的累积个人识别率为0.999 999 93,累积非父排除率为0.992 287.结论 构建的miniSTR荧光复合扩增体系,操作简便,分型准确,重复性好,对降解检材有效,易于在法医实验室推广应用,可对现有试剂盒起补充作用.%Objective To develop a fluorescent multiplex system of 8 non-CODIS miniSTR and Amelogenin for forensic purpose.Methods Eight highly polymorphic non-CODIS miniSTR loci, D20S1082, D6S474,D12ATA63, D9S1122, D2S1776, D1S1627, D3S4529 and D2S441 were selected, and a fluorescent multiplex system including these loci and the genderspeeifie Amelogenin was developed through redesigning primers,labeling fluorescence dye, and optimizing experiment conditions.204 randomly selected individuals of Guangzhou Han population, members of 30 families and 30 degraded samples were genotyped using this system.Results Tested by the new multiplex system,all the loci can generate stable and full profiles with amplieons less than 200bp in size, which resulted in art increased overall typing success rate for degraded DNA samples.The cumulative power of discrimination and probability of exclusion were 0.999 999 93 and 0.992 287 respectively in Guangzhou Han population.Conclusion The established fluorescent multiplex system was robust, sensitive and stable, and is of high value in forensic application.It can serve as a new

  11. Assessment of SAR and thermal changes near a cochlear implant system for mobile phone type exposures.

    Science.gov (United States)

    McIntosh, Robert L; Iskra, Steve; McKenzie, Raymond J; Chambers, John; Metzenthen, Bill; Anderson, Vitas

    2008-01-01

    A cochlear implant system is a device used to enable hearing in people with severe hearing loss and consists of an internal implant and external speech processor. This study considers the effect of scattered radiofrequency fields when these persons are subject to mobile phone type exposure. A worst-case scenario is considered where the antenna is operating at nominal full power, the speech processor is situated behind the ear using a metallic hook, and the antenna is adjacent to the hook and the internal ball electrode. The resultant energy deposition and thermal changes were determined through numerical modelling. With a 900 MHz half-wave dipole antenna producing continuous-wave (CW) 250 mW power, the maximum 10 g averaged SAR was 1.31 W/kg which occurred in the vicinity of the hook and the ball electrode. The maximum temperature increase was 0.33 degrees C in skin adjacent to the hook. For the 1800 MHz antenna, operating at 125 mW, the maximum 10 g averaged SAR was 0.93 W/kg in the pinna whilst the maximum temperature change was 0.16 degrees C. The analysis predicts that the wearer complies with the radiofrequency safety limits specified by the International Commission on Non-Ionizing Radiation Protection (ICNIRP), the Institute of Electrical and Electronics Engineers (IEEE), and the Australian Radiation Protection and Nuclear Safety Agency (ARPANSA) for 900 and 1800 MHz mobile phone type exposure and thus raises no cause for concern. The resultant temperature increase is well below the maximum rise of 1 degrees C recommended by ICNIRP. Effects in the cochlea were insignificant.

  12. Immediate Implants: Clinical Guidelines for Esthetic Outcomes

    Directory of Open Access Journals (Sweden)

    Mohammad A. Javaid

    2016-06-01

    Full Text Available Research has shown that tooth loss results in morphological changes in alveolar ridge that may influence the subsequent implant placement. Immediate implant placement was introduced as a possible means to limit bone resorption and reduce the number of surgical procedures following tooth extraction. Histological and clinical evidence from human clinical studies showing efficacy of immediate implants has come to light over the last decade or so. However, immediate implant placement is a challenging surgical procedure and requires proper case selection and surgical technique. Furthermore, there appears to be a lack of clinical guidelines for immediate implant placement case selection. Therefore, the aim of this mini-review is to analyze critical evidence from human studies in order to establish clinical guidelines which may help clinicians in case selection when considering immediate implant placement protocol.

  13. Systemic Assessment of Calcium and Phosphorus Level after Implantation of Porous Iron in Rats

    Science.gov (United States)

    Siallagan, S. F.; Amelia, F.; Utami, N. D.; Ulum, M. F.; Boediono, A.; Estuningsih, S.; Hermawan, H.; Noviana, D.

    2017-07-01

    One of important aspects in bone healing process is physiological level of calcium (Ca), and phosphorus (P) that can be altered by implantation of biodegradable porous iron. Therefore, this study aims to investigate the concentration of Ca, P and Ca/P ratio in the peripheral blood during the implantation period up to 4 months. Forty adult male Sprague Dawley rats were used and divided into 3 groups receiving different pore size of iron implants (pore size 450, 580, 800μm) and one group of sham. The implants (5x2x0.5mm) were inserted into flat bone defects at latero-medial of femoral bone. Blood sample was taken from ventral tail artery before and after 4 month of implantation. Calcium and P concentrations in the blood were determined by BA-88A Semi-Auto Chemistry Analyzer. Results showed that concentration of Ca and P are slightly higher after implantation than before implantation, except for the 450μm group. The Ca/P ratio before and after implantation was increased in the sham group, and decreased in the 450 and 800μm groups. Concentration of Ca, P and Ca/P ratio insignificantly change between before and 4 months after surgery in some groups.

  14. Operative technique for insertion of a totally implantable system for venous access.

    Science.gov (United States)

    Sterchi, J M; Fulks, D; Cruz, J; Paschold, E

    1986-10-01

    A totally implantable venous access device is described and a step by step technique for implanting the device is given. Among 203 patients in whom the technique has been used, thrombosis of the subclavian or jugular vein has occurred in only three. There have been no pulmonary complications, and only three devices have been removed because of infection.

  15. Parameters of passive fit using a new technique to mill implant-supported superstructures: an in vitro study of a novel three-dimensional force measurement-misfit method.

    Science.gov (United States)

    Tahmaseb, Ali; van de Weijden, J J; Mercelis, Peter; De Clerck, Renaat; Wismeijer, Daniel

    2010-01-01

    The objectives of this study are to describe, in vitro, a novel technique to measure the misfit of digitally designed and manufactured implant-supported frameworks according to a new concept based on computer-guided surgery in combination with previously placed mini-implants. Also, the digitally created framework and an impression-based milled structure were compared using strain gauge measurements. Acrylic resin and plaster models were prepared to represent the edentulous mandible. After insertion of three mini-implants in the acrylic resin model, a cone-beam computed tomographic scan was performed. The data were imported to planning software, where six implants were virtually inserted. A drill guide and titanium framework were designed and milled using a fully digital computer-aided design/computer-assisted machining protocol. Six implants were inserted using the drill guide attached to the mini-implants. After an impression was made of the acrylic resin model with six implants, the second model (plaster model) was prepared. A second milled titanium structure was fabricated following optical scanning of the acrylic resin model. Strain gauge measurements were done on both structures attached to both models. To validate the results, a high-accuracy industrial optical scanning system was used to capture all connection geometry and the measurements were compared. The accuracy of the digital superstructures was 19, 22, and 10 Microm with standard deviations (SD) of 19.2 (17.9), 21.5 (28.3), and 10.3 (10.1) Microm for the x-, y-, and z-axes, respectively. For the impression-based superstructure the measured misfit was 11, 20, and 17 Microm, with SD 11.8 (10.5), 19.7 (11.7), and 16.7 (8.2) Microm for the x-, y-, and z-axes, respectively. The misfit of the digitally designed and produced superstructure on the digitally planned and inserted implants was clinically insignificant.

  16. Mini-Med School Planning Guide

    Science.gov (United States)

    National Institutes of Health, Office of Science Education, 2008

    2008-01-01

    Mini-Med Schools are public education programs now offered by more than 70 medical schools, universities, research institutions, and hospitals across the nation. There are even Mini-Med Schools in Ireland, Malta, and Canada! The program is typically a lecture series that meets once a week and provides "mini-med students" information on some of the…

  17. Multicultural Mini-Units. Elementary.

    Science.gov (United States)

    Flora, Sherrill B.

    The teaching mini-units in this teacher's guide are designed for use with elementary level students. Thematic study units are given for each of the following countries or continents: Africa, Australia, Brazil, Canada, China, England, France, Germany, Greece, India, Israel, Italy, Japan, Mexico, Netherlands, Russia, Spain, Sweden, Thailand, and the…

  18. Multicultural Mini-Units. Elementary.

    Science.gov (United States)

    Flora, Sherrill B.

    The teaching mini-units in this teacher's guide are designed for use with elementary level students. Thematic study units are given for each of the following countries or continents: Africa, Australia, Brazil, Canada, China, England, France, Germany, Greece, India, Israel, Italy, Japan, Mexico, Netherlands, Russia, Spain, Sweden, Thailand, and the…

  19. Development of implantable hemodialysis system using PES membranes with high water-permeability.

    Science.gov (United States)

    To, N; Sanada, I; Ito, H; Morita, S; Kanno, Y; Miki, N

    2015-08-01

    This paper presents development of high water-permeable dialysis membranes. We proposed the system that does not use dialysis fluid for the implantable micro dialysis treatment and development of such membranes is crucial. We developed micro dialysis system composed by nanoporous membranes and microfluidic channels in our prior work. The membranes were made of nanoporous polyethersulfone (PES), which was not water-permeable. By not using dialysate, our device can be simplified because the pumps and storage tanks for the dialysis fluid are not necessary. This treatment is termed as hemofiltration. We measured the water permeability of PES membrane with respect to the concentrations of the PES, the additives, and the solvents in the casting solution. We could find the membranes with sufficiently high water permeability through in vitro experiments using a syringe pomp and whole cow blood, and the membrane had enough mechanical strength. We conducted experiments with multi-layered device in in vitro and in vivo using rats, where the system was connected to the vein and artery. We successfully collected the filtrate beyond target line, which was set by a medical doctor, without any leakage of blood from the device. The results verified that the filtration device can be scaled-up by increasing a number of the layer. We connected the device to a rat for 5h. It was verified the device maintained almost constant water permeability beyond our target line.

  20. First clinical implant of the VentrAssist left ventricular assist system as destination therapy for end-stage heart failure.

    Science.gov (United States)

    Esmore, Donald S; Kaye, David; Salamonsen, Robert; Buckland, Mark; Rowland, Michael; Negri, Justin; Rowley, Yvonne; Woodard, John; Begg, John R; Ayre, Peter; Rosenfeldt, Franklin L

    2005-08-01

    The VentrAssist device left ventricular assist system, designed for permanent implantation, is a novel centrifugal pump with a hydrodynamically suspended rotor. The first human implant was into a 72-year-old man with New York Heart Association (NYHA) class IV heart failure due to idiopathic dilated cardiomyopathy. The implant and recovery were uneventful, and the patient survives at 17 months, is NYHA class II, and lives at home. This device shows promise in end-stage heart failure for permanent implantation and bridge to transplantation.

  1. Mini gas turbines. Study related to energy efficient cogeneration applications for new cogeneration markets; Mini gasturbiner. Udredning vedr. energieffektive kraftvarmeapplikationer til nye kraftvarmemarkeder

    Energy Technology Data Exchange (ETDEWEB)

    Mikkelsen, J.B.; Weel Hansen, M.; Aastrupgaard, N.P.

    2000-12-01

    The aim of the project is to investigate, design and increase the energy efficiency in new cogeneration/cooling systems, which are based on new developed mini gas turbines. Hereby cogeneration can primarily based on natural gas and bio-fuels be distributed to new market segments. The advantages of mini gas turbines (electric power output 20 - 250 kW) are that they have only one rotating part, are simple and small and ought to have a low specific plant price, as they are mass-produced and represent a further development based on turbo-chargers equipped with high speed generators. By means of recuperation even in small plants relatively high electric efficiency of over 30% are obtained. The biggest advantage is, however, very low operating cost, high level of reliability and small environmental impacts. Therefore, it is expected that the technology could have a large impact on new markets for small and medium-sized enterprises, resulting in renewed large-scale conversion to cogeneration. In the present project the varias conditions related to the following are investigated: 1) Use of mini gas turbine as oil-/gas burner. 2) Simple cogeneration plant with recuperation gas turbine. 3) Mini gas turbines in cogeneration/refrigerating plants for supermarkets. 4) Mini gas turbines for drying plants. 5) VOC destruction in mini gas turbines. 6) Direct driven compressors. 7) Conditions related to part load. 8) The economy of the different mini gas turbine applications. 9) Environmental issues by use of mini gas turbines. (EHS)

  2. Irradiation influence on Mylar and Makrofol induced by argon ions in a plasma immersion ion implantation system

    Energy Technology Data Exchange (ETDEWEB)

    Hassan, A. [Accelerators & Ion Sources Department, Nuclear Research Center, Atomic Energy Authority, P.O. 13759, Cairo (Egypt); El-Saftawy, A.A., E-mail: aama1978@yahoo.com [Accelerators & Ion Sources Department, Nuclear Research Center, Atomic Energy Authority, P.O. 13759, Cairo (Egypt); Aal, S.A. Abd El [Central Lab. for Elemental & Isotopic Analysis, Nuclear Research Center, Atomic Energy Authority, P.O. 13759, Cairo (Egypt); Ghazaly, M. El [Physiology Department, College of Medicine, Taif University, P.O. 888, Taif (Saudi Arabia); Physics Department, Faculty of Science, Zagazig University, P.O. 44519, Zagazig (Egypt)

    2015-08-30

    Highlights: • A home-built plasma immersion ion implantation system was tested in modifying surfaces. • Wettability modifications within the energy range 10 keV implantation are not investigated elsewhere, up to our knowledge. • The wettability of Mylar and Makrofol surface was enhanced by the dual effect of ion implantation and plasma treatment. • The improved wettability was found to depend on both surface roughness and chemistry. • The adhesive bonding and surface energy of the polymers are improved. - Abstract: Mylar and Makrofol polycarbonate polymers were irradiated by Ar ions in a plasma immersion ion implantation (PIII) system. The surface wettability of both polymers was investigated by employing the contact angle method. The measured contact angles were found to depend on the surface layer properties. Good wetting surfaces were found to depend not only on surface roughness but also on its chemistry that analyzed by Fourier transform infrared (FTIR) spectroscopy. Surfaces topography and roughness was investigated and correlated to their surface energy which studied with the aid of acid-base model for evaluating the improvement of surface wettability after irradiation. PIII improves polymers surface properties efficiently in a controllable way.

  3. Modulation of the maternal immune system by the pre-implantation embryo

    Directory of Open Access Journals (Sweden)

    Walker Caroline G

    2010-08-01

    Full Text Available Abstract Background A large proportion of pregnancy losses occur during the pre-implantation period, when the developing embryo is elongating rapidly and signalling its presence to the maternal system. The molecular mechanisms that prevent luteolysis and support embryo survival within the maternal environment are not well understood. To gain a more complete picture of these molecular events, genome-wide transcriptional profiles of reproductive day 17 endometrial tissue were determined in pregnant and cyclic Holstein-Friesian dairy cattle. Results Microarray analyses revealed 1,839 and 1,189 differentially expressed transcripts between pregnant and cyclic animals (with ≥ 1.5 fold change in expression; P-value Conclusion The maternal immune system actively surveys the uterine environment during early pregnancy. The embryo modulates this response inducing the expression of endometrial molecules that suppress the immune response and promote maternal tolerance to the embryo. During this period of local immune suppression, genes of the innate immune response (in particular, antimicrobial genes may function to protect the uterus against infection.

  4. Indicators of soil quality in the implantation of no-till system with winter crops

    Directory of Open Access Journals (Sweden)

    Marco Antonio Nogueira

    Full Text Available We assessed the effect of different winter crops on indicators of soil quality related to C and N cycling and C fractions in a Rhodic Kandiudult under no-till system at implantation, during two growing seasons, in Londrina PR Brazil. The experimental design was randomized blocks with split-plot in time arrangement, with four replications. The parcels were the winter crops: multicropping of cover crops with black oat (Avena strigosa, hairy vetch (Vicia villosa and fodder radish (Raphanus sativus; sunflower (Heliantus annuus intercropped with Urochloa ruziziensis; corn (Zea mays intercropped with Urochloa; and corn; fodder radish; or wheat (Triticum aestivum as sole crops. The subplots were the years: 2008 and 2009. Determinations consisted of total organic C, labile and resistant C, total N, microbial biomass C and N, the C/N ratio of soil organic matter, and the microbial quotient (qMic, besides microbiological and biochemical attributes, assessed only in 2009. The attributes significantly changed with the winter crops, especially the multicropping of cover crops and fodder radish, as well as effect of years. Despite stimulating the microbiological/biochemical activity, fodder radish cropping decreased the soil C in the second year, likewise the wheat cropping. The multicropping of cover crops in winter is an option for management in the establishment of no-till system, which contributes to increase the concentrations of C and stimulate the soil microbiological/biochemical activity.

  5. PreImplantation factor (PIF*) regulates systemic immunity and targets protective regulatory and cytoskeleton proteins.

    Science.gov (United States)

    Barnea, Eytan R; Hayrabedyan, Soren; Todorova, Krassimira; Almogi-Hazan, Osnat; Or, Reuven; Guingab, Joy; McElhinney, James; Fernandez, Nelson; Barder, Timothy

    2016-07-01

    Secreted by viable embryos, PIF is expressed by the placenta and found in maternal circulation. It promotes implantation and trophoblast invasion, achieving systemic immune homeostasis. Synthetic PIF successfully transposes endogenous PIF features to non-pregnant immune and transplant models. PIF affects innate and activated PBMC cytokines and genes expression. We report that PIF targets similar proteins in CD14+, CD4+ and CD8+ cells instigating integrated immune regulation. PIF-affinity chromatography followed by mass-spectrometry, pathway and heatmap analysis reveals that SET-apoptosis inhibitor, vimentin, myosin-9 and calmodulin are pivotal for immune regulation. PIF acts on macrophages down-stream of LPS (lipopolysaccharide-bacterial antigen) CD14/TLR4/MD2 complex, targeting myosin-9, thymosin-α1 and 14-3-3eta. PIF mainly targets platelet aggregation in CD4+, and skeletal proteins in CD8+ cells. Pathway analysis demonstrates that PIF targets and regulates SET, tubulin, actin-b, and S100 genes expression. PIF targets systemic immunity and has a short circulating half-life. Collectively, PIF targets identified; protective, immune regulatory and cytoskeleton proteins reveal mechanisms involved in the observed efficacy against immune disorders. Copyright © 2016 Elsevier GmbH. All rights reserved.

  6. Development of data communication system with ultra high frequency radio wave for implantable artificial hearts.

    Science.gov (United States)

    Tsujimura, Shinichi; Yamagishi, Hiroto; Sankai, Yoshiyuki

    2009-01-01

    In order to minimize infection risks of patients with artificial hearts, wireless data transmission methods with electromagnetic induction or light have been developed. However, these methods tend to become difficult to transmit data if the external data transmission unit moves from its proper position. To resolve this serious problem, the purpose of this study is to develop a prototype wireless data communication system with ultra high frequency radio wave and confirm its performance. Due to its high-speed communication rate, low power consumption, high tolerance to electromagnetic disturbances, and secure wireless communication, we adopted Bluetooth radio wave technology for our system. The system consists of an internal data transmission unit and an external data transmission unit (53 by 64 by 16 mm, each), and each has a Bluetooth module (radio field intensity: 4 dBm, receiver sensitivity: -80 dBm). The internal unit also has a micro controller with an 8-channel 10-bit A/D converter, and the external unit also has a RS-232C converter. We experimented with the internal unit implanted into pig meat, and carried out data transmission tests to evaluate the performance of this system in tissue thickness of up to 3 mm. As a result, data transfer speeds of about 20 kbps were achieved within the communication distance of 10 m. In conclusion, we confirmed that the system can wirelessly transmit the data from the inside of the body to the outside, and it promises to resolve unstable data transmission due to accidental movements of an external data transmission unit.

  7. Mini-Tn7 transposons for site-specific tagging of bacteria with fluorescent proteins

    DEFF Research Database (Denmark)

    Lambertsen, L.; Sternberg, Claus; Molin, Søren

    2004-01-01

    The mini-Tn7 transposon system is a convenient tool for site-specific tagging of bacteria in which the tagging DNA is inserted at a unique and neutral chromosomal site. We have expanded the panel of mini-Tn7 delivery plasmids expressing different fluorescent proteins (stable and unstable) from th...

  8. Validity of a short clinical interview for psychiatric diagnosis : the mini-SCAN

    NARCIS (Netherlands)

    Nienhuis, F. J.; van de Willige, G.; Rijnders, C. A. Th.; de Jonge, P.; Wiersma, D.

    2010-01-01

    Background To promote clinical application of the Schedules for Clinical Assessment in Neuropsychiatry (SCAN) system a shorter version (the mini-SCAN) was devised. Its psychometric properties were unknown. Aims To establish the validity and practical properties of the mini-SCAN. Method One hundred a

  9. Validity of a short clinical interview for psychiatric diagnosis: the mini-SCAN.

    NARCIS (Netherlands)

    Nienhuis, F.J.; Willige, G. van de; Rijnders, C.A.T.; Jonge, P. de; Wiersma, D.

    2010-01-01

    BACKGROUND: To promote clinical application of the Schedules for Clinical Assessment in Neuropsychiatry (SCAN) system a shorter version (the mini-SCAN) was devised. Its psychometric properties were unknown. AIMS: To establish the validity and practical properties of the mini-SCAN. METHOD: One hundre

  10. Mini AERCam Inspection Robot for Human Space Missions

    Science.gov (United States)

    Fredrickson, Steven E.; Duran, Steve; Mitchell, Jennifer D.

    2004-01-01

    The Engineering Directorate of NASA Johnson Space Center has developed a nanosatellite-class free-flyer intended for future external inspection and remote viewing of human spacecraft. The Miniature Autonomous Extravehicular Robotic Camera (Mini AERCam) technology demonstration unit has been integrated into the approximate form and function of a flight system. The spherical Mini AERCam free flyer is 7.5 inches in diameter and weighs approximately 10 pounds, yet it incorporates significant additional capabilities compared to the 35 pound, 14 inch AERCam Sprint that flew as a Shuttle flight experiment in 1997. Mini AERCam hosts a full suite of miniaturized avionics, instrumentation, communications, navigation, imaging, power, and propulsion subsystems, including digital video cameras and a high resolution still image camera. The vehicle is designed for either remotely piloted operations or supervised autonomous operations including automatic stationkeeping and point-to-point maneuvering. Mini AERCam is designed to fulfill the unique requirements and constraints associated with using a free flyer to perform external inspections and remote viewing of human spacecraft operations. This paper describes the application of Mini AERCam for stand-alone spacecraft inspection, as well as for roles on teams of humans and robots conducting future space exploration missions.

  11. Spinal shape modulation in a porcine model by a highly flexible and extendable non-fusion implant system

    NARCIS (Netherlands)

    Wessels, Martijn; Hekman, Edsko E. G.; Kruyt, Moyo C.; Castelein, Rene M.; Homminga, Jasper J.; Verkerke, Gijsbertus J.

    2016-01-01

    In vivo evaluation of scoliosis treatment using a novel approach in which two posterior implants are implanted: XSLAT (eXtendable implant correcting Scoliosis in LAT bending) and XSTOR (eXtendable implant correcting Scoliosis in TORsion). The highly flexible and extendable implants use only small, b

  12. Single surgical procedure combining epicardial pacemaker implantation and subsequent extraction of the infected pacing system for pacemaker-dependent patients.

    Science.gov (United States)

    Amraoui, Sana; Barandon, Laurent; Whinnett, Zachary; Ploux, Sylvain; Labrousse, Louis; Denis, Arnaud; Oses, Pierre; Ritter, Philippe; Haissaguerre, Michel; Bordachar, Pierre

    2013-08-01

    Management of pacemaker infection in pacing-dependent patients is often challenging. Typically, temporary pacing is used while antibiotic therapy is given for a number of days before reimplantation of a new endocardial system. This results in a prolonged hospital stay and complications associated with temporary pacing. In this study, we examine the feasibility of performing a single combined procedure of epicardial pacemaker implantation followed by system extraction. One hundred consecutive infected pacemaker-dependent patients underwent implantation of 2 epicardial ventricular leads and were converted to a ventricular demand pacing system. The infected pacing system was then extracted during the same procedure. Patients were followed up for 12 months. Significant pericardial bleeding developed during the procedure in 3 patients. The presence of the pericardial drain positioned during the implantation of the epicardial pacing system meant that cardiac tamponade did not occur, allowing surgical repair with sternotomy to be carried out under stable hemodynamic conditions. Two of these 100 patients died in the 30-day postoperative period; 1 death was due to septic shock and 1 to pulmonary distress. Median 1-year epicardial pacing thresholds were stable and excellent (1.4 ± 0.9 volts). However, 1 of the 2 leads developed increased thresholds in 6 patients, which led to the exclusive use of other ventricular lead. A single combined procedure of surgical epicardial pacemaker implantation and pacemaker system extraction appears to be a safe and effective method for managing pacemaker-dependent patients with infected pacemakers. Copyright © 2013 The American Association for Thoracic Surgery. Published by Mosby, Inc. All rights reserved.

  13. Summer Mini Atomiade June 2016

    CERN Multimedia

    Staff Association

    2016-01-01

    The Mini Atomiade are coming to CERN! Members of Clubs supported by the CERN Staff Association and in conjunction with ASCERI (Association of the Sports Communities of the European Research Institutes) will be organising the summer games at the beginning of June. ASCERI aims to contribute to a united Europe through regular sports meetings, bringing together members of public Research Institutes at European level. The Association's members come from over 40 Research Institutes spanning 16 countries. Numerous sports and leisure activities are represented at regular events and each tournament is organised by a different research institute. Clubs in conjunction with the CERN Staff Association have sent teams to previous winter and summer games and now, the CERN Club’s Coordination Committee (CCC) has now taken on the challenge of organising a Mini Atomiade from Friday June 3rd to Monday June 6th 2016 in Divonne-les-Bains. The games are made up of four different tournaments/competitions: Small Fi...

  14. A programmable energy efficient readout chip for a multiparameter highly integrated implantable biosensor system

    Science.gov (United States)

    Nawito, M.; Richter, H.; Stett, A.; Burghartz, J. N.

    2015-11-01

    In this work an Application Specific Integrated Circuit (ASIC) for an implantable electrochemical biosensor system (SMART implant, Stett et al., 2014) is presented. The ASIC drives the measurement electrodes and performs amperometric measurements for determining the oxygen concentration, potentiometric measurements for evaluating the pH-level as well as temperature measurements. A 10-bit pipeline analog to digital (ADC) is used to digitize the acquired analog samples and is implemented as a single stage to reduce power consumption and chip area. For pH measurements, an offset subtraction technique is employed to raise the resolution to 12-bits. Charge integration is utilized for oxygen and temperature measurements with the capability to cover current ranges between 30 nA and 1 μA. In order to achieve good performance over a wide range of supply and process variations, internal reference voltages are generated from a programmable band-gap regulated circuit and biasing currents are supplied from a wide-range bootstrap current reference. To accommodate the limited available electrical power, all components are designed for low power operation. Also a sequential operation approach is applied, in which essential circuit building blocks are time multiplexed between different measurement types. All measurement sequences and parameters are programmable and can be adjusted for different tissues and media. The chip communicates with external unites through a full duplex two-wire Serial Peripheral Interface (SPI), which receives operational instructions and at the same time outputs the internally stored measurement data. The circuit has been fabricated in a standard 0.5-μm CMOS process and operates on a supply as low as 2.7 V. Measurement results show good performance and agree with circuit simulation. It consumes a maximum of 500 μA DC current and is clocked between 500 kHz and 4 MHz according to the measurement parameters. Measurement results of the on-chip ADC show a

  15. Comparison of Retentive Force in Four Attachment Systems in Implant- Supported Overdenture of the Lower Arch

    Directory of Open Access Journals (Sweden)

    Ahmadzadeh A.

    2012-06-01

    Full Text Available tement of Problem: Along with the rapid population growth in recent decades, there has been an increase in the number of edentulous patients who have complications with conventional denture. This entails the use of dentures, such as implant overdenture, which are more efficacious. Purpose: The purpose of this study is to compare four types of different attachm-ent systems; two prefabricated and two castable attachments. Materials and Method: A model of lower edentulous arch was constructed out of dental stone. Two parallel implants were placed in the canine region. A single cast metal chrome cobalt framework was fabricated to provide reinforcement for experimental overdentures and it splinted the two attachments on the cast. To conduct this study, four groups with six numbers of attachments in each group (superflex ball, locator, castable ball on bar, castable bar were selected. All the samples were put in a Universal Testing Machine and a tension force with the speed of 50 mm/ min was exerted to separate the framework from the cast. The tension force was recorded and the first two prefabricated attachments (superflex ball and locator were compared with the second two castable attachments (ball on bar, castable bar.Results: The findings of this study revealed that retention force of castable ball on bar was greater than the other three attachments (35.31±3.14N. With regard to the strength of retentive force, superflex ball took the second place (33.33± 3.11 N and locator (20.90± 3.74N and castable bar (14.74± 1.15N took the third and the forth places, respectively ( p >0.001. Conclusion: The retentive force of castable ball on bar was similar to that of superflex ball. Therefore, the use of this cheap attachment; castable ball on bar, is preferred to its prefabricated counterparts. The retentive force of this kind of attachment is greater than expensive locators. The retentive force of castable bar was similar to that of locator, although

  16. Mini-Rocket User Guide

    Science.gov (United States)

    2007-08-01

    Missile Research , Development, and Engineering Center and Ray Sells DESE Research , Inc. 315 Wynn Drive Huntsville, AL 35805 August 2007...with the minirock command, you are prompted for a filename: Mini-Rocket v1.01 by Ray Sells, DESE Research , Inc. Input file: - Output is printed...nancv.bucher@us.army.mil Commander, U.S. Army ARDEC Picatinny Arsenal, NJ 07806-5000 ATTN: AMSRD-AR-AIS -SA DESE Research , Inc. 3 15 Wynn Drive

  17. Introduction to Mini Muon Tracker

    Energy Technology Data Exchange (ETDEWEB)

    Borozdin, Konstantin N. [Los Alamos National Laboratory

    2012-08-13

    Using a mini muon tracker developed at the Los Alamos National Laboratory we performed experiments of simple landscapes of various materials, including TNT, 9501, lead, tungsten, aluminium, and water. Most common scenes are four two inches thick step wedges of different dimensions: 12-inch x 12-inch, 12-inch x 9-inch, 12-inch x 6-inch, and 12-inch x 3-inch; and a one three inches thick hemisphere of lead with spherical hollow, and a similar full lead sphere.

  18. Assessment of an implant-skin interface scoring system for external skeletal fixation of dogs.

    Science.gov (United States)

    McDonald-Lynch, Mischa B; Marcellin-Little, Denis J; Roe, Simon C; Lascelles, B Duncan X; Trumpatori, Brian J; Griffith, Emily H

    2015-11-01

    OBJECTIVE To assess intraobserver repeatability and interobserver and in vivo versus photographic agreement of a scoring system for the implant-skin interface (ISI) of external skeletal fixation (ESF). SAMPLE 42 photographs of ISIs from 18 dogs for interobserver agreement and intraobserver repeatability and 27 photographs of ISIs from 6 dogs for in vivo versus photograph agreement. PROCEDURES An ISI inflammation scoring system was developed. It included scales for 6 metrics (erythema, drainage amount, drainage type, swelling, hair loss or lack of hair regrowth, and granulation tissue). Photographs of the ISI of ESF were obtained by use of a standard protocol and evaluated to determine intraobserver repeatability and interobserver agreement (Cronbach α; 4 raters) of the ISI score. Agreement between in vivo and photographic ISI scores (2 raters) and correlation between median scores across metrics were evaluated. RESULTS 42 photographs met the inclusion criteria. Overall intraclass correlation coefficients ranged from 0.922 to 0.975. Interobserver overall Cronbach α ranged from 0.835 to 0.943. For in vivo versus photographic assessment, 27 ISIs in 6 dogs and their photographs were evaluated. The Cronbach α for both raters ranged from 0.614 to 0.938. Overall, the Cronbach α ranged from 0.725 to 0.932. Mean photographic scores were greater than mean in vivo scores for each metric. Pearson correlation coefficients ranged from 0.221 to 0.923. Erythema, swelling, and granulation were correlated with all other metrics. CONCLUSIONS AND CLINICAL RELEVANCE In this study, an ISI scoring system used in this study had high repeatability and agreement and may therefore be considered for use in clinical situations. Photographic scores were not equivalent to in vivo scores and should not be used interchangeably.

  19. Improvement of the insertion axis for cochlear implantation with a robot-based system.

    Science.gov (United States)

    Torres, Renato; Kazmitcheff, Guillaume; De Seta, Daniele; Ferrary, Evelyne; Sterkers, Olivier; Nguyen, Yann

    2017-02-01

    It has previously reported that alignment of the insertion axis along the basal turn of the cochlea was depending on surgeon' experience. In this experimental study, we assessed technological assistances, such as navigation or a robot-based system, to improve the insertion axis during cochlear implantation. A preoperative cone beam CT and a mastoidectomy with a posterior tympanotomy were performed on four temporal bones. The optimal insertion axis was defined as the closest axis to the scala tympani centerline avoiding the facial nerve. A neuronavigation system, a robot assistance prototype, and software allowing a semi-automated alignment of the robot were used to align an insertion tool with an optimal insertion axis. Four procedures were performed and repeated three times in each temporal bone: manual, manual navigation-assisted, robot-based navigation-assisted, and robot-based semi-automated. The angle between the optimal and the insertion tool axis was measured in the four procedures. The error was 8.3° ± 2.82° for the manual procedure (n = 24), 8.6° ± 2.83° for the manual navigation-assisted procedure (n = 24), 5.4° ± 3.91° for the robot-based navigation-assisted procedure (n = 24), and 3.4° ± 1.56° for the robot-based semi-automated procedure (n = 12). A higher accuracy was observed with the semi-automated robot-based technique than manual and manual navigation-assisted (p robot-based system reduces both the error and the variability of the alignment with a defined optimal axis.

  20. Image-guided smart laser system for precision implantation of cells in cartilage

    Science.gov (United States)

    Katta, Nitesh; Rector, John A.; Gardner, Michael R.; McElroy, Austin B.; Choy, Kevin C.; Crosby, Cody; Zoldan, Janet; Milner, Thomas E.

    2017-03-01

    State-of-the-art treatment for joint diseases like osteoarthritis focus on articular cartilage repair/regeneration by stem cell implantation therapy. However, the technique is limited by a lack of precision in the physician's imaging and cell deposition toolkit. We describe a novel combination of high-resolution, rapid scan-rate optical coherence tomography (OCT) alongside a short-pulsed nanosecond thulium (Tm) laser for precise cell seeding in cartilage. The superior beam quality of thulium lasers and wavelength of operation 1940 nm offers high volumetric tissue removal rates and minimizes the residual thermal footprint. OCT imaging enables targeted micro-well placement, precise cell deposition, and feature contrast. A bench-top system is constructed using a 15 W, 1940 nm, nanosecond-pulsed Tm fiber laser (500 μJ pulse energy, 100 ns pulse duration, 30kHz repetition rate) for removing tissue, and a swept source laser (1310 ± 70 nm, 100 kHz sweep rate) for OCT imaging, forming a combined Tm/OCT system - a "smart laser knife". OCT assists the smart laser knife user in characterizing cartilage to inform micro-well placement. The Tm laser creates micro-wells (2.35 mm diameter length, 1.5 mm width, 300 μm deep) and micro-incisions (1 mm wide, 200 μm deep) while OCT image-guidance assists and demonstrates this precision cutting and cell deposition with real-time feedback. To test micro-well creation and cell deposition protocol, gelatin phantoms are constructed mimicking cartilage optical properties and physiological structure. Cell viability is then assessed to illustrate the efficacy of the hydrogel deposition. Automated OCT feedback is demonstrated for cutting procedures to avoid important surface/subsurface structures. This bench-top smart laser knife system described here offers a new image-guided approach to precise stem cell seeding that can enhance the efficacy of articular cartilage repair.

  1. Development of a wireless intra-ocular pressure monitoring system for incorporation into a therapeutic glaucoma drainage implant

    Science.gov (United States)

    Kakaday, Tarun; Plunkett, Malcolm; McInnes, Steven; Li, Jim S. Jimmy; Voelcker, Nicolas H.; Craig, Jamie E.

    2008-12-01

    Glaucoma is a common cause of blindness. Wireless, continuous monitoring of intraocular pressure (IOP) is an important, unsolved goal in managing glaucoma. An IOP monitoring system incorporated into a glaucoma drainage implant (GDI) overcomes the design complexity associated with incorporating a similar system in a more confined space within the eye. The device consists of a micro-electro-mechanical systems (MEMS) based capacitive pressure sensor integrated with an inductor printed directly onto a polyimide printed circuit board (PCB). The device is designed to be incorporated onto the external plate of a therapeutic GDI. The resonance frequency changes as a function of IOP, and is tracked remotely using a spectrum analyzer. A theoretical model for the reader antenna was developed to enable maximal inductive coupling with the IOP sensor implant. Pressure chamber tests indicate that the sensor implant has adequate sensitivity in the IOP range with excellent reproducibility over time. Additionally, we show that sensor sensitivity does not change significantly after encapsulation with polydimethylsiloxane (PDMS) to protect the device from fluid environment. In vitro experiments showed that the signal measured wirelessly through sheep corneal and scleral tissue was adequate indicating potential for using the system in human subjects.

  2. Preoperative parameters and their prognostic value in amyotrophic lateral sclerosis patients undergoing implantation of a diaphragm pacing stimulation system

    Directory of Open Access Journals (Sweden)

    Aydin Sanli

    2017-01-01

    Full Text Available Introduction: Amyotrophic lateral sclerosis (ALS is a progressive neuromuscular disease with devastating and fatal respiratory complications. Diaphragm pacing stimulation (DPS is a treatment option in diaphragm insufficient ALS patients. Ventilatory insufficiency depending on diaphragmatic failure is treated by the present study aimed to investigate prognostic value of preoperative clinical and functional characteristics of ALS patients undergoing implantation of a DPS system and to determine appropriate indications for the DPS system. Methods: The study included 34 ALS patients implanted with DPS system. All patients underwent multidisciplinary and laboratory evaluations before the surgery. The laboratory examinations included pulmonary function tests and arterial blood gas analysis. Survival rates were recorded in a 2-year follow-up after the surgery. Results: Twenty-eight of 34 patients with ALS survived after a 2-year follow-up. These patients were younger than those who died and had the disease for a longer time; however, the differences were not significant. Both right and left hemidiaghragms were thicker in the survived patients (P < 0.0001 for each. Pulmonary function tests revealed no significant differences between the patients who survived. Arterial blood gas analysis demonstrated lower partial pressure of carbon dioxide in the survived patients (P = 0.025. Conclusions: DPS implantation was more efficacious in ALS patients with mild respiratory failure and thicker diaphragm. Predictors of long-term effectiveness of DPS system are needed to be addressed by large-scale studies.

  3. 时尚着,运动着——MINI Cooper S & MINI Cooper S Clubman

    Institute of Scientific and Technical Information of China (English)

    于英钊

    2008-01-01

    <正>在成功地推出MINI Cooper和MINI Cooper Clubman车型后,宝马中国将MINI的顶级车型Cooper S引入中国大陆市场。不久前,MINI Cooper S和MINI Cooper S Clubman在上海联袂登场,使MINI品牌产品系列更加丰富。作为车系中的高端车型, MINI Cooper S和MINI Cooper S Clubman价格不菲,售价分别为人民币385,000元和410,000元。

  4. Construction of Mini-PACS based on free software in basic hospitals%基于免费软件的基层医院Mini-PACS构建

    Institute of Scientific and Technical Information of China (English)

    吴杰; 王树峰

    2013-01-01

    Objective To construct Mini-PACS based on free software in basic hospitals. Methods The Mini-PACS was constructed by using free software of dcm4chePACS and Xiphoid and connecting with CT, DR, MR in the Department of Radiology. Results The Mini-PACS system constructed is stable, which realized the share of imaging data in the Department of Radiology. Conclusion Mini-PACS system based on free software could fulfill the need of the Department of Radiology in basic hospitals.%目的 利用免费PACS软件在基层医院自建Mini-PACS系统.方法 应用免费软件dcm4chePACS与Xiphoid,连接基层医院放射科CT、DR、MR等数字化影像设备,构建Mini-PACS.结果 实现了放射科影像资料的共享,系统运行稳定.结论 应用免费dcm4chePACS与Xiphoid构建Mini-PACS系统,可满足基层医院放射科需要.

  5. Cyborg mini-trainer.

    Science.gov (United States)

    Mosso, José L; Nieto, Jesus J; Carbajal, Manuel F; Marmolejo, Jorge; Ochoa, Enrique; De La Fuente, Mireya; Almazan, Andrew; Obrador, Tomas

    2009-01-01

    We present the smallest surgical trainer with a total weight of 400 gr, built in aluminum of 25 cm large and 24 cm wide, and 23 cm high. It's a system integrated by a small and open module, a lamp and a microcamera connected to a Head Mounted display. It holds two endoscopic instruments, and items to make knots or sutures and enhance visual-motor coordination. The vision we got is by a small microcamera displayed to a Head Mounted Display HMD. This surgical trainer is the smallest in the worldwide, easy to install, and easy to carry.

  6. Cooling down MiniGRAIL to milli-Kelvin temperatures

    NARCIS (Netherlands)

    de Waard, A.; de Waard, A.; Gottardi, L.; Bassan, M.; Coccia, E.; Fafone, V.; Flokstra, Jakob; Karbalai-Sadegh, A.; Minenkov, Y.; Moleti, A.; Pallottino, G.V.; Podt, M.; Pors, B.J.; Reincke, W; Rocchi, A.; Shumack, A.; Srinivas, S.; Visco, M.; Frossati, G.

    2004-01-01

    The latest developments in the construction of the ultra-cryogenic spherical detector MiniGRAIL are presented. The room temperature part of the vibration isolation system was improved and provided with an attenuation of about 60 dB around 3 kHz. The transfer function of the cryogenic stages gave abo

  7. Ductless Mini-Split Heat Pump Comfort Evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Roth, K.; Sehgal, N.; Akers, C.

    2013-03-01

    Field tests were conducted in two homes in Austin, TX to evaluate the comfort performance of ductless mini-split heat pumps (DMSHPs), measuring temperature and relative humidity measurements in four rooms in each home before and after retrofitting a central HVAC system with DMSHPs.

  8. Cooling down MiniGRAIL to milli-Kelvin temperatures

    NARCIS (Netherlands)

    Waard, de A.; Gottardi, L.; Bassan, M.; Coccia, E.; Fafone, V.; Flokstra, J.; Karbalai-Sadegh, A.; Minenkov, Y.; Moleti, A.; Pallottino, G.V.; Podt, M.; Pors, B.J.; Reincke, W.; Rocchi, A.; Shumack, A.; Srinivas, S.; Visco, M.; Frossati, G.

    2004-01-01

    The latest developments in the construction of the ultra-cryogenic spherical detector MiniGRAIL are presented. The room temperature part of the vibration isolation system was improved and provided with an attenuation of about 60 dB around 3 kHz. The transfer function of the cryogenic stages gave abo

  9. Teeth movement in denture and implant-supported prosthesis influenced by microwave flask systems

    Science.gov (United States)

    Consani, Rafael L.X.; Sonehara, Leonardo G.; Mesquita, Marcelo F.; Barão, Valentim A.R.; Caetano, Conrado R.

    2015-01-01

    Background/Aims This study evaluated the teeth movement in maxillary dentures and mandibular implantsupported prostheses processed by microwave flasks. Methods A model mounted on articulator was used to manufacture Co-Cr frameworks. Pins were placed for measurements on the incisal edge of upper and lower central incisors (I), buccal cusp of first upper and lower premolars (PM), and mesiobuccal cusps of upper and lower second molars (M). Distances I-I (incisor to incisor), PM-PM (premolar to premolar), M-M (molar to molar), RI-RM (right incisor to right molar), and LI-LM (left incisor to left molar) were measured before and after processing using a microscope (0.0005 mm). Vertical misfit between abutment and implant platform was evaluated for regions A (left distal implant), B (left median implant), C (medial implant), D (right median implant), and E (right distal implant) in predetermined labial and lingual sites. Prostheses were divided into groups G1 – conventional flask, and G2 – experimental HH flask. Acrylic resin was microwaved at 1400 W (30% for 3 min, 0% for 3 min, and 60% for 3 min). Horizontal teeth displacement and vertical misfit between abutment and implant platform were considered before and after procedures. Data were submitted to three-way ANOVA and Tukey's test (α = 0.05). Results Except for M-M distance, the teeth showed displacements without statistical difference for prosthesis and flask factors. There was no significant difference for vertical misfit values for both flasks. Conclusion Diferente flasks did not cause significant changes in the teeth displacement, except for M-M. Vertical misfit values were not influenced by the flasks. PMID:26605143

  10. Cochlear Implant

    Directory of Open Access Journals (Sweden)

    Mehrnaz Karimi

    1992-04-01

    Full Text Available People with profound hearing loss are not able to use some kinds of conventional amplifiers due to the nature of their loss . In these people, hearing sense is stimulated only when the auditory nerve is activated via electrical stimulation. This stimulation is possible through cochlear implant. In fact, for the deaf people who have good mental health and can not use surgical and medical treatment and also can not benefit from air and bone conduction hearing aids, this device is used if they have normal central auditory system. The basic parts of the device included: Microphone, speech processor, transmitter, stimulator and receiver, and electrode array.

  11. In vivo evaluation of an implantable portal pump system for augmenting liver perfusion.

    Science.gov (United States)

    Jiao, L R; Seifalian, A M; Davidson, B R; Habib, N

    2000-08-01

    Increasing portal inflow in cirrhosis using a mechanical pump reduces portal venous pressure and improves liver function. A pump has been developed for portal vein implantation in human cirrhosis. This study describes the initial in vivo evaluation in a porcine model. Five Large White pigs underwent laparotomy and exposure of the liver. Flow in the hepatic artery, portal vein and hepatic microcirculation was monitored continuously. Hepatic tissue oxygenation was measured by near-infrared spectroscopy. After baseline measurements the pump was inserted into the portal vein. Pump flow rate was then increased stepwise to 50 per cent over the baseline value for a period of 2 h. The pump was then stopped for 20 min and left in situ while continuing to collect systemic and hepatic haemodynamic data. The animal was killed and biopsies for histological examination were taken from the liver, small intestine and spleen. The baseline total hepatic blood flow was 626(39) ml/min; the hepatic artery supplied 18.4(2.1) per cent and the portal vein 81.6(2.1) per cent. The pump was inserted successfully in all animals without surgical complications. During surgical insertion of the pump, the temporary portal vein occlusion resulted in a significant rise in hepatic artery blood flow (22(3) per cent; P Portal vein flow was augmented by pumping; there was a significant correlation between the pump motor speed and portal vein flow (P oxygenation (P portal vein. Portal venous blood flow can be increased up to 50 per cent with a resultant increase in flow in the hepatic microcirculation and hepatic oxygenation and without adverse effects on either hepatic or systemic haemodynamics.

  12. Injection Molding of Titanium Alloy Implant For Biomedical Application Using Novel Binder System Based on Palm Oil Derivatives

    Directory of Open Access Journals (Sweden)

    R. Ibrahim

    2010-01-01

    Full Text Available Problem statement: Titanium alloy (Ti6Al4V has been widely used as an implant for biomedical application. In this study, the implant had been fabricated using high technology of Powder Injection Molding (PIM process due to the cost effective technique for producing small, complex and precision parts in high volume compared with conventional method through machining. Approach: Through PIM, the binder system is one of the most important criteria in order to successfully fabricate the implants. Even though, the binder system is a temporary, but failure in the selection and removal of the binder system will affect on the final properties of the sintered parts. Therefore, the binder system based on palm oil derivative which is palm stearin had been formulated and developed to replace the conventional binder system. Results: The rheological studies of the mixture between the powder and binders system had been determined properly in order to be successful during injection into injection molding machine. After molding, the binder held the particles in place. The binder system had to be removed completely through debinding step. During debinding step, solvent debinding and thermal pyrolysis had been used to remove completely of the binder system. The debound part was then sintered to give the required physical and mechanical properties. The in vitro biocompatibility also was tested using Neutral Red (NR and mouse fibroblast cell lines L-929 for the direct contact assay. Conclusion: The results showed that the properties of the final sintered parts fulfill the Standard Metal Powder Industries Federation (MPIF 35 for PIM parts except for tensile strength and elongation due to the formation of titanium carbide. The in vitro biocompatibility on the extraction using mouse fibroblast cell line L-929 by means of NR assays showed non toxic for the sintered specimen titanium alloy parts.

  13. Accuracy of a newly developed cone-beam computerized tomography-aided surgical guidance system for dental implant placement: an ex vivo study.

    Science.gov (United States)

    Murat, Sema; Kamburoğlu, Kivanç; Özen, Tuncer

    2012-12-01

    The aim of the present study was to measure the accuracy of the cone-beam computerized tomography (CBCT)- aided StentCad Beyond surgical guidance system and to compare bone-supported and tooth/bone-supported guidance by using this system in dental implant placement ex vivo. Five cadaver mandibles were scanned using an Iluma CBCT scanner. After scanning, DICOM slices were transferred to the StentCad Beyond implant simulation software, which was used for preoperative implant planning. Using the StentCad Beyond guidance system, 9 implant drills were inserted using a bone-supported guidance system and 11 using a tooth/bone-supported guidance system. Mandibles were scanned again and these data were transferred to the StentCad Beyond software. Pre- and postoperative information was superimposed using the Rhinoceros version 4 software program, and deviations between planned and actual drill positions were calculated for each implant. In addition, differences between bone-supported and tooth/bone-supported guidance systems were analyzed by t-test, with a significance level of P .05); however, statistically significant differences between groups were found in mean horizontal coronal deviation (P = .016) and mean horizontal apical deviation (P = .047). The StentCad Beyond system was found to be a reliable guide for placing implants ex vivo.

  14. Review of Strategies and Technologies for Demand-Side Management on Isolated Mini-Grids

    Energy Technology Data Exchange (ETDEWEB)

    Harper, Meg [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2013-03-01

    This review provides an overview of strategies and currently available technologies used for demandside management (DSM) on mini-grids throughout the world. For the purposes of this review, mini-grids are defined as village-scale electricity distribution systems powered by small local generation sources and not connected to a main grid.1 Mini-grids range in size from less than 1 kW to several hundred kW of installed generation capacity and may utilize different generation technologies, such as micro-hydro, biomass gasification, solar, wind, diesel generators, or a hybrid combination of any of these. This review will primarily refer to AC mini-grids, though much of the discussion could apply to DC grids as well. Many mini-grids include energy storage, though some rely solely on real-time generation.

  15. Cochlear Implants

    Science.gov (United States)

    A cochlear implant is a small, complex electronic device that can help to provide a sense of sound. People who are ... of-hearing can get help from them. The implant consists of two parts. One part sits on ...

  16. Cochlear Implants

    Science.gov (United States)

    ... imaging (MRI) scans, to evaluate your inner ear anatomy. Cochlear implant surgery Cochlear implant surgery is usually performed as an outpatient procedure under general anesthesia. An incision is made behind the ear ...

  17. Model Documentation for the MiniCAM

    Energy Technology Data Exchange (ETDEWEB)

    Brenkert, Antoinette L.; Smith, Steven J.; Kim, Son H.; Pitcher, Hugh M.

    2003-07-17

    The MiniCAM, short for the Mini-Climate Assessment Model, is an integrated assessment model of moderate complexity focused on energy and agriculture sectors. The model produces emissions of greenhouse gases (carbon dioxide, methane and nitrous oxide) and other radiatively important substances such as sulfur dioxide. Through incorporation of the simple climate model MAGICC, the consequences of these emissions for climate change and sea-level rise can be examined. The MiniCAM is designed to be fast and flexible.

  18. Mini-mast CSI testbed user's guide

    Science.gov (United States)

    Tanner, Sharon E.; Pappa, Richard S.; Sulla, Jeffrey L.; Elliott, Kenny B.; Miserentino, Robert; Bailey, James P.; Cooper, Paul A.; Williams, Boyd L., Jr.; Bruner, Anne M.

    1992-01-01

    The Mini-Mast testbed is a 20 m generic truss highly representative of future deployable trusses for space applications. It is fully instrumented for system identification and active vibrations control experiments and is used as a ground testbed at NASA-Langley. The facility has actuators and feedback sensors linked via fiber optic cables to the Advanced Real Time Simulation (ARTS) system, where user defined control laws are incorporated into generic controls software. The object of the facility is to conduct comprehensive active vibration control experiments on a dynamically realistic large space structure. A primary goal is to understand the practical effects of simplifying theoretical assumptions. This User's Guide describes the hardware and its primary components, the dynamic characteristics of the test article, the control law implementation process, and the necessary safeguards employed to protect the test article. Suggestions for a strawman controls experiment are also included.

  19. Contracted Nose after Silicone Implantation: A New Classification System and Treatment Algorithm

    Science.gov (United States)

    Kim, Yong Kyu; Shin, Seungho; Kim, Joo Heon

    2017-01-01

    Background Silicone implants are frequently used in augmentation rhinoplasty in Asians. A common complication of silicone augmentation rhinoplasty is capsular contracture. This is similar to the capsular contracture after augmentation mammoplasty, but a classification for secondary contracture after augmentation rhinoplasty with silicone implants has not yet been established, and treatment algorithms by grade or severity have yet to be developed. Methods Photographs of 695 patients who underwent augmentation rhinoplasty with a silicone implant from May 2001 to May 2015 were analyzed. The mean observation period was 11.4 months. Of the patients, 81 were male and 614 were female, with a mean age of 35.9 years. Grades were assigned according to postoperative appearance. Grade I was a natural appearance, as if an implant had not been inserted. Grade II was an unnatural lateral margin of the implant. Clearly identifiable implant deviation was classified as grade III, and short nose deformation was grade IV. Results Grade I outcomes were found in 498 patients (71.7%), grade II outcomes in 101 (14.5%), grade III outcomes in 75 (10.8%), and grade IV outcomes in 21 patients (3.0%). Revision surgery was indicated for the 13.8% of all patients who had grade III or IV outcomes. Conclusions It is important to clinically classify the deformations due to secondary contracture after surgery and to establish treatment algorithms to improve scientific communication among rhinoplasty surgeons. In this study, we suggest guidelines for the clinical classification of secondary capsular contracture after augmentation rhinoplasty, and also propose a treatment algorithm. PMID:28194349

  20. High capacity implantable data recorders: system design and experience in canines and Denning black bears.

    Science.gov (United States)

    Laske, Timothy G; Harlow, Henry J; Werder, Jon C; Marshall, Mark T; Iaizzo, Paul A

    2005-11-01

    Implantable medical devices have increasingly large capacities for storing patient data as a diagnostic aid and to allow patient monitoring. Although these devices can store a significant amount of data, an increased ability for data storage was required for chronic monitoring in recent physiological studies. Novel high capacity implantable data recorders were designed for use in advanced physiological studies of canines and free-ranging black bears. These hermitically sealed titanium encased recorders were chronically implanted and programmed to record intrabody broadband electrical activity to monitor electrocardiograms and electromyograms, and single-axis acceleration to document relative activities. Changes in cardiac T-wave morphology were characterized in the canines over a 6 month period, providing new physiological data for the design of algorithms and filtering schemes that could be employed to avoid inappropriate implantable defibrillator shocks. Unique characteristics of bear hibernation physiology were successfully identified in the black bears, including: heart rate, respiratory rate, gross body movement, and shiver An unanticipated high rejection rate of these devices occurred in the bears, with five of six being externalized during the overwintering period, including two devices implanted in the peritoneal cavity. High capacity implantable data recorders were designed and utilized for the collection of long-term physiological data in both laboratory and extreme field environments. The devices described were programmable to accommodate the diverse research protocols. Additionally, we have described substantial differences in the response of two species to a common device. Variations in the foreign body response of different mammals must be identified and taken into consideration when choosing tissue-contacting materials in the application of biomedical technology to physiologic research.

  1. Contracted Nose after Silicone Implantation: A New Classification System and Treatment Algorithm

    Directory of Open Access Journals (Sweden)

    Yong Kyu Kim

    2017-01-01

    Full Text Available BackgroundSilicone implants are frequently used in augmentation rhinoplasty in Asians. A common complication of silicone augmentation rhinoplasty is capsular contracture. This is similar to the capsular contracture after augmentation mammoplasty, but a classification for secondary contracture after augmentation rhinoplasty with silicone implants has not yet been established, and treatment algorithms by grade or severity have yet to be developed.MethodsPhotographs of 695 patients who underwent augmentation rhinoplasty with a silicone implant from May 2001 to May 2015 were analyzed. The mean observation period was 11.4 months. Of the patients, 81 were male and 614 were female, with a mean age of 35.9 years. Grades were assigned according to postoperative appearance. Grade I was a natural appearance, as if an implant had not been inserted. Grade II was an unnatural lateral margin of the implant. Clearly identifiable implant deviation was classified as grade III, and short nose deformation was grade IV.ResultsGrade I outcomes were found in 498 patients (71.7%, grade II outcomes in 101 (14.5%, grade III outcomes in 75 (10.8%, and grade IV outcomes in 21 patients (3.0%. Revision surgery was indicated for the 13.8% of all patients who had grade III or IV outcomes.ConclusionsIt is important to clinically classify the deformations due to secondary contracture after surgery and to establish treatment algorithms to improve scientific communication among rhinoplasty surgeons. In this study, we suggest guidelines for the clinical classification of secondary capsular contracture after augmentation rhinoplasty, and also propose a treatment algorithm.

  2. iPad mini for dummies

    CERN Document Server

    Baig, Edward C

    2014-01-01

    Find out why the iPad mini has never been bigger This new edition of iPad mini For Dummies covers all the latest tips and tricks for getting an even bigger bang out of your iPad mini. Presented in full-color and written in the straightforward but fun language that has defined the For Dummies brand for more than twenty years, this friendly guide walks you through the multitouch interface, going online, getting connected, packing your iPad mini with apps, games, e-books, photos, music, and movies, synchronizing your data, texting with iMessage, working with Siri, importing pictures and launching

  3. Mini-atlas of the marmoset brain.

    Science.gov (United States)

    Senoo, Aya; Tokuno, Hironobu; Watson, Charles

    2015-04-01

    A mini-atlas of the brain is designed to help students and young researchers who are not familiar with neuroanatomy. In the mini-atlas, a limited number of important nuclei and fiber tracts are shown on a small number of brain sections from posterior end to the anterior end of the brain. The first mini-atlas was introduced for the rat brain (Watson et al., 2010). Here we present a mini-atlas of the common marmoset (Callithrix jaccus), which is one of representative experimental primates for modern neuroscience. We further discuss the differences of brain structures between rodents and primates.

  4. A novel shaft-less double suction mini pump

    Institute of Scientific and Technical Information of China (English)

    NISHI; Michihiro

    2010-01-01

    A novel double suction shaft-less mini pump was developed for heat control of small energy systems in this study.The mini pump impeller with an exit diameter of 40 mm was combined with the motor rotor supported by the hybrid dynamic bearing.The specific speed of the pump was 125 min-1 m3 min-1 m.The hydraulic performance of the pump was investigated experimen-tally under four rotational speeds.From the test results,it was recognized that the pump could provide a flow discharge of 5 L/min and head of 1.5 m,which are applicable for the heat control system of a 3 kW fuel cell.A three-dimensional turbulent flow simulation in the pump was also conducted near the design point.The numerical results showed that the average hydraulic performance of the mini pump was predicted reasonably.From the internal flow simulation,it was revealed that the favorable inflow condition upstream of impeller inlet could be attained by applying the double suction shaft-less design for the mini pump.

  5. Moroccan colloquial Arabic version of the Mini International Neuropsychiatric Interview (MINI): qualitative and quantitative validation.

    Science.gov (United States)

    Kadri, N; Agoub, M; El Gnaoui, S; Alami, Kh Mchichi; Hergueta, T; Moussaoui, D

    2005-03-01

    The validation of mini international neuropsychiatric interview (MINI) into Moroccan Colloquial Arabic language demonstrated good psychometric properties. The concordance between translated MINI's and expert diagnoses was good with kappa values greater than 0.80. The reliability inter-rater and test-retest were excellent with kappa values above 0.80 and 0.90, respectively.

  6. Teach yourself visually Mac Mini

    CERN Document Server

    Hart-Davis, Guy

    2012-01-01

    The perfect how-to guide for visual learners Apple?s Mac Mini packs a powerful punch is in a small package, including both HDMI and Thunderbolt ports plus the acclaimed OS X. But if you want to get the very most from all this power and versatility, be sure to get this practical visual guide. With full-color, step-by-step instructions as well as screenshots and illustrations on every page, it clearly shows you how to accomplish tasks rather than burying you in pages of text. Discover helpful visuals and how-tos on the OS, hardware specs, Launchpad, the App Store, multimedia capabilities (such

  7. A short-term clinical evaluation of effectiveness of the fixed implantation of Ankylos implant system with multiple crowns%Ankylos种植系统多牙固定修复短期临床疗效评价

    Institute of Scientific and Technical Information of China (English)

    郭照中; 张恒; 杨旭; 周婷婷; 刘学

    2012-01-01

    目的 评价Ankylos种植体用于固定修复多牙缺失的临床应用效果.方法 临床选择21例多牙缺失患者完成Ankylos 68枚种植体进行潜入式种植手术,部分骨量不足的患者,同期使用膜引导骨再生术、上颌窦内提升术或上颌窦外提升术.Ⅱ期手术两周后,按照常规方法完成金钯合金烤瓷冠修复.术后随访,检查修复体与基台的稳定性,种植体周围牙龈组织的健康状况;通过X线检查观察骨组织的吸收情况及基台的密合程度;调查患者对种植义齿咀嚼、美观功能的主观满意度.种植后及义齿修复后的临床观察期为1~2.5年.结果 冠桥修复后,1例患者的1枚种植体在种植修复后1个月时,发生种植体周围炎;1例在修复后1年烤瓷冠崩瓷;其余种植体均稳定,无明显骨吸收,种植体基台界面密合,牙龈组织健康.按种植成功标准,修复成功66枚,成功率97.1%;失败2枚,占2.9%.结论 Ankylos种植体用于多牙缺失的固定修复具有良好的临床效果.%Objective To evaluate the clinical effects of Ankylos implant system to restore the loss of more than one teeth. Methods Totally, 21 cases with loss of more than one teeth were investigated, and a total of 68 implants were placed from January, 2008 to May, 2010. All the patients had undergone routinely two-stage surgery. When patients showed deficient alveolar ridge, guided bone regeneration (GBR), osteotome sinus floor elevation, lateral antroslomy surgery with simultaneous placement of implants were applied. They were restored with platinum eeramic crowns. All implants were followed up, and records were kept about stability of the implants and abutments, conditions of the surrounding soft tissues, sealability of implant abutment junction, the marginal bone loss through X-ray checking, satisfaction of the patients to mastication, and other aspects of the restorations. The follow- up time was 1-2.5 years. Results Among all of the

  8. Quality control of system of imaging for rectal ultrasound for implants seed prostate low rate; Control de calidad del sistem de imagen por ecografia rectal para implantes de semillas de prostata de baja tasa

    Energy Technology Data Exchange (ETDEWEB)

    Luquero Llopis, N.; Ferrer Gracia, C.; Huertas Martinez, C.; Huerga Cabrerizo, C.; Corredoira Silva, E.; Serrada Hierro, A.

    2013-07-01

    In this work, the objective is the evaluation of the image system used in implants of prostate of low rate held at our hospital, for maximum control on the placement of the seeds in the patient and therefore carried out dosimetry. (Author)

  9. Analog Integrated Circuit and System Design for a Compact, Low-Power Cochlear Implant

    NARCIS (Netherlands)

    Ngamkham, W.

    2015-01-01

    Cochlear Implants (CIs) are prosthetic devices that restore hearing in profoundly deaf patients by bypassing the damaged parts of the inner ear and directly stimulating the remaining auditory nerve fibers in the cochlea with electrical pulses. This thesis describs the electronic circuit design of va

  10. The effects of low dose chemotherapy for advanced hepatocellular carcinoma through percutaneously implanted intra-arterial port system

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Hyun Seok; Won, Je Hwan; Yoo, Byung Moo; Kim, Young Soo; Cho, Sung Won [Ajou Univ. College of Medicine, Suwon (Korea, Republic of); Park, Dong Won [Suwon Medical Center, Suwon (Korea, Republic of)

    2001-07-01

    To investigate the effects of low-dose FP (5-Fluorouracil[5FU]+Cispatin[CDDP]) therapy through a percutaneously implanted intra-arterial port system in patients with advanced hepatocellular carcinoma (HCC). Twenty-five patients with advanced HCCs and portal vein thrombosis, or large HCCs which were unresectable or for which transarterial chemoembolization was thought to be ineffective, underwent intra-arterial port implantation. The mean maxinal diameter of these tumors was 13.7 (range, 5-21.5) cm, and they were located at the right lobe (n=18), the left lobe(n=3), or throughout the liver (n=4). Tumor thrombosis was detected in the main (n=14), right (n=3) and left portal vein(n=1), the right portal vein and inferior vena cava(n=2), and the inferior vena cava(n=1). The four others patients had no portal vein thrombosis. All intra-arterial port implantations were performed percutaneously in the angiographic ward through the right or left common femoral artery. The port chamber was implanted in the inguinal area and fixed using histoacryl. For intra-arterial chemotherapy, 5-FU (250 mg/day) and CDDP (10 mg/day) were used for five days every four weeks. In order to observe changes in tumor size, follow-up CT scanning was performed every two months. Implantation of the port system was successful in all cases, and patients underwent between one and eleven (mena, 3.9) sessions of chemotherapy. Port-and catheter-related complications, namely dislodgement of the catheter(n=2), wound infection(n=2), migration of the coil(n=1) and catheter occlusion(n=1) occurred in six patients (24%), and chemotherapy-related complications, namely liver failure(n=3) and gastric ulcer bleeding(n=1), in four (16%). A complete response, i. e. the disappearance of tumor thrombosis of the portal vein, was achieved in one patient (4%), a partial response in three (12%), and a minor response in four (16%); the overall response rate was 32% and the mean survival period was 7.6 months. Low-dose FP

  11. Photovoltaic energy mini-generation: Future perspectives for Portugal

    Energy Technology Data Exchange (ETDEWEB)

    Carvalho, Duarte [Physics Department, University of Evora, R. Romao Ramalho, 59, 7000-671 Evora (Portugal); Wemans, Joao [WS Energia SA, Taguspark Edificio Tecnologia II, Pav. 46, 2740-257 Porto Salvo (Portugal); Lima, Joao [Agropower, Moinho de Pisoes, Santana do Campo, 7040-130 Arraiolos (Portugal); Malico, Isabel, E-mail: imbm@uevora.pt [Physics Department, University of Evora, R. Romao Ramalho, 59, 7000-671 Evora (Portugal); IDMEC/IST, Technical University of Lisbon, Mechanical Engineering Department, Av. Rovisco Pais, 1049-001 Lisbon (Portugal)

    2011-09-15

    This paper evaluates the benefits of developing the mini-generation PV market in Portugal. It presents the legal framework and current status of the Portuguese PV electricity sector, and compares the country to other European nations: France, Germany, Greece, Italy, Spain and the United Kingdom. A model that combines PVGIS with a self-developed financial tool is used to assess the feasibility of a 150 kW mini-generation system using five different technologies: fixed mount, single-axis tracking, double-axis tracking, low concentration and medium concentration (MCPV). The profitability of the mini-generation systems in the seven countries studied is calculated and compared. According to this analysis, MCPV and, of the conventional technologies, the single-axis tracking systems are the most profitable technologies. Despite the attractiveness of the current Portuguese feed-in tariffs and of the abundant solar resource, investors are discouraged and the country's PV market is far from mature. Specific mini-generation regulations should focus on a fast and transparent licensing procedure and should promote the access to financing. This would attract new investments, which would result in the growth of the PV electricity produced, and would help Portugal to meet its European Union Renewable Energy targets. - Highlights: > This work promotes the development of a mini-generation PV market in Portugal. > The Portuguese current status and legal framework is compared to other EU countries. > The profitability of 5 different PV technologies is compared for 7 European countries. > The Portuguese growth potential for PV energy is still big. > Portugal, due to its radiation levels, presents excellent investment opportunities.

  12. Balloon-expanding stent and delivery system for transcatheter aortic valve implantation:An animal study

    Institute of Scientific and Technical Information of China (English)

    Xiang Chen; Fei-Yu Wang; Guo-Jun Chu; Yu-Feng Zhu; Hong-Wen Tan; Xian-Xian Zhao; Yong-Wen Qin; Jun-Bo Ge

    2015-01-01

    Objective: To evaluate the feasibility and satefy of transcatheter aortic valve implantation in animals by using a new balloon-expanding valved stent. Methods: The balloon-expandable stent is made from cobalt-based alloy material and designed with a tubular, slotted structure. Fresh bovine pericardium was treated, sutured and fixed on the balloon-expandable stent. Ten healthy sheep (five males and five females), weighing an average of (25.16 ± 1.83) kg, were selected to undergo transcatheter implantation of the valve stents. The function of the valve stent was evaluated by angiography, echocardiography, and histology six months after the procedure. Results: Of the ten experimental sheep, two sheep died during the operation because the higher position of the artificial valve affected the opening of the coronary artery. We successfully implanted the aortic valve stent in other eight sheep;however, one sheep died of heart failure two weeks after the operation due to the lower position of the valve stent. The valve stents were implanted in the desired position in seven sheep. Ascending aortic angiographic and autoptic findings immediately after the operation confirmed the satisfactory location and function of the valved stent. Echocardiography, angiography, and histology at six post-operative months confirmed the satisfactory location and function of the valve stent. Conclusion: We successfully implanted our new valve stent as a replacement of native aortic valve via the transcatheter route with satisfactory outcome. Copyright © 2015, Chinese Medical Association Production. Production and hosting by Elsevier B.V. on behalf of KeAi Communications Co., Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

  13. Emergency and elective implantation of covered stent systems in iatrogenic arterial injuries

    Energy Technology Data Exchange (ETDEWEB)

    Goltz, J.P.; Kickuth, R. [Universitaetsklinikum Wuerzburg (Germany). Inst. fuer Roentgendiagnostik; Bastuerk, P.; Hoppe, H.; Triller, J. [Universitaetsspital Bern (Switzerland). Inst. fuer Diagnostische, Interventionelle und Paediatrische Radiologie

    2011-07-15

    Purpose: To evaluate the effectiveness and safety of covered stents for the management of iatrogenic arterial injury. Materials and Methods: Between 03/1998 and 12/2009, 31 patients underwent selective covered stent implantation after iatrogenic arterial injury. 12/31 of these patients (38.7 %) were hemodynamically unstable. Six different endovascular covered stent types were utilized. The primary endpoints of this study were technical and clinical success and rates of minor and major complications. Results: Initial angiograms demonstrated active extravasation in 19 (61.3 %) patients and pseudoaneurysms in 12 (38.7 %) patients. The following sites of bleeding origin were detected: axillary artery, subclavian artery, common iliac artery, external iliac artery, internal iliac artery, common femoral artery, superficial femoral artery, popliteal and fibular artery, femoro-popliteal and popliteo-crural bypasses, common hepatic artery, aberrant hepatic artery, cystic and gastroduodenal artery. In all patients bleeding was effectively controlled by covered stent implantation resulting in an immediate technical success of 100 %. Clinical success attributed to covered stent implantation was documented in 30 of the 31 patients (96.8 %). Major complications included death in four patients (11.1 %), acute thrombosis with arm ischemia in one patient (2.8 %) and stent fracture with associated pseudoaneurysm in another patient (2.8 %). In 2/31 patients (6.5 %) covered stent failure was detected and successfully treated by implantation of a second covered stent. Conclusion: Emergency and elective implantation of covered stents may be used for minimally invasive and effective management of iatrogenic arterial injury. (orig.)

  14. Experimental study on cyclosporine A drug delivery system in prevention of posterior capsule opacification after intraocular lens implantation in rabbits

    Institute of Scientific and Technical Information of China (English)

    Pei Cheng; Sun Naixue

    2008-01-01

    Objective To study the effect of cyclosporine A drug delivery system (CsA-DDS) on the prevention of posterior capsule opacification (PCO) after experimental intraocular lens implantation in rabbit eyes. Methods Twenty healthy New Zealand white rabbits, whose left eyes and right eyes were used respectively as experiment eyes and controls, were subjected to extracapsular lens extraction and artificial lens implantation. During the operation, CsA-DDS with poly (lactideco-glycolide) as carriers or empty DDS was implanted in the capsular bag for the experimental eyes and controls respectively. After the operation, anterior chamber reaction, intraocular pressure (IOP) and CsA concentration were monitored and twelve weeks after the operation, the eyes were extracted for histopathological and morphological examinations. Results There were no differences between the two groups in conjunctival congestion,IOP change and anterior chamber reaction. PCO was less severe in the experimental eyes than in the controls. Light microscopy revealed that posterior capsular membrane in the experimental eyes was slick, with no obvious proliferation,whereas in the controls, there were lens epithelial cell proliferation and cortex regeneration of different degrees.Morphological examination with electron microscope showed that in the experimental eyes, lens epithelial cells did not function actively and apoptosis occurred, whereas in the controls, epithelial cells presented active function. No marked ultrastructural changes were found in either group. Conclusion Cs-DDS can inhibit PCO after intraocular lens implantation in rabbit eyes and does not have toxic effects on the surrounding ocular tissues. Therefore, it has a good potential for clinical use in prevention of PCO.

  15. Pacemaker dependency after transcatheter aortic valve implantation with the self-expanding Medtronic CoreValve System.

    Science.gov (United States)

    van der Boon, Robert M A; Van Mieghem, Nicolas M; Theuns, Dominic A; Nuis, Rutger-Jan; Nauta, Sjoerd T; Serruys, Patrick W; Jordaens, Luc; van Domburg, Ron T; de Jaegere, Peter P T

    2013-09-30

    To determine pacemaker (PM) dependency at follow-up visit in patients who underwent new permanent pacemaker implantation (PPI) following transcatheter aortic valve implantation (TAVI). Single center prospective observational study including 167 patients without previous PM implantation who underwent TAVI with the self-expanding Medtronic CoreValve System (MCS) between November 2005 and February 2011. PM dependency was defined by the presence of a high degree atrioventricular block (HDAVB; second [AV2] and third degree [AV3B]), or a slow (<30 bpm) or absent ventricular escape rhythm during follow-up PM interrogation. A total of 36 patients (21.6%) received a new PM following TAVI. The indication for PM was AV2B (n=2, 5.6%), AV3B (n=28, 77.8%), postoperative symptomatic bradycardia (n=3, 8.3%), brady-tachy syndrome (n=1, 2.8%), atrial fibrilation with slow response (n=1, 2.8%) and left bundle branch block (n=1, 2.8%). Long term follow-up was complete for all patients and ranged from 1 to 40 months (median (IQR): 11.5 (5.0-18.0 months). Of those patients with a HDAVB, 16 out of the 30 patients (53.3%) were PM independent at follow-up visit (complete or partial resolution of the AV conduction abnormality). Overall, 20 out of the 36 patients (55.6%) who received a new PM following TAVI were PM independent at follow-up. Partial and even complete resolution of peri-operative AV conduction abnormalities after MCS valve implantation occurred in more than half of the patients. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  16. MUSIC AND COCHLEAR IMPLANTS

    Institute of Scientific and Technical Information of China (English)

    Mao Yitao; Xu Li

    2013-01-01

    Currently, most people with modern multichannel cochlear implant systems can understand speech in qui-et environment very well. However, studies in recent decades reported a lack of satisfaction in music percep-tion with cochlear implants. This article reviews the literature on music ability of cochlear implant users by presenting a systematic outline of the capabilities and limitations of cochlear implant recipients with regard to their music perception as well as production. The review also evaluates the similarities and differences be-tween electric hearing and acoustic hearing regarding music perception. We summarize the research results in terms of the individual components of music (e.g., rhythm, pitch, and timbre). Finally, we briefly intro-duce the vocal singing of prelingually-deafened children with cochlear implants as evaluated by acoustic measures.

  17. Mini-cutting of Eucalyptus benthamii: effect of the genotype, IBA, zinc, boron and shoots collection

    Directory of Open Access Journals (Sweden)

    Gilvano Ebling Brondani

    2014-03-01

    Full Text Available The aim of this study was to evaluate the induction of adventitious rooting in Eucalyptus benthamii mini-cuttings regarding to genotype, Zn and B concentrations, shoot collections and IBA application. Shoots for the mini-cuttings confection were collected from mini-stumps fertigated with nutrient solutions containing different concentrations of Zn and B (S1 - free of Zn and B, S2 - 0.5 mg L-1 Zn, S3 - 0.5 mg L-1 B, S4 - 0.5 mg L-1 Zn and B, S5 - 1.0 mg L-1 Zn and B, S6 - 2.0 mg L-1 Zn and B. The basal portion of the mini-cuttings was immersed for 10 s in a solution containing 2,000 mg L-1IBA. A free IBA solution was used as control. The mini-cuttings survival in greenhouse, shade-house and in full sun area were evaluated. In full sun area, only the rooted mini-cuttings were evaluated, and of these, the total length of the root system was measured. The adventitious rooting of Eucalyptus benthamii mini-cuttings depended of the genotype, Zn and B concentrations, shoots collections and IBA application. In general, the adventitious rooting percentage was low, and the genotypes were considered difficult to propagation by mini-cuttings technique. The mini-cuttings collected of mini-stumps fertigated with nutrient solutions S5 (1.0 mg L-1 Zn and B and S6 (2.0 mg L-1 Zn and B associated with the presence of IBA in the concentration of 2,000 mg L-1 presented the greater adventitious rooting percentage.

  18. Cyclic distillation technology - A mini-review

    DEFF Research Database (Denmark)

    Bîldea, Costin Sorin; Pătruţ, Cătălin; Jørgensen, Sten Bay;

    2016-01-01

    Process intensification in distillation systems has received much attention during the past decades, with the aim of increasing both energy and separation efficiency. Various techniques, such as internal heat-integrated distillation, membrane distillation, rotating packed bed, dividing-wall columns...... and reactive distillation were studied and reported in literature. All these techniques employ the conventional continuous counter-current contact of vapor and liquid phases. Cyclic distillation technology is based on an alternative operating mode using separate phase movement which leads to key practical...... advantages in both chemical and biochemical processes. This article provides a mini-review of cyclic distillation technology. The topics covered include the working principle, design and control methods, main benefits and limitations as well as current industrial applications. Cyclic distillation can...

  19. CLINICAL APPLICATION OF IMMEDIATE IMPLANT PLACEMENT OF ZIMMER DENTAL IMPLANT SYSTEM IN THE MOLAR REGIONS%Zimmer种植系统在后牙即刻种植的临床应用研究

    Institute of Scientific and Technical Information of China (English)

    容明灯; 张雪洋; 刘卫平; 卢海宾; 李少冰; 罗维; 苏媛; 黄雁红; 金爱琼

    2014-01-01

    Objective To observe the clinical effects of the immediate implant placement of Zimmer dental implant system in the molar regions.Methods 14 cases with a total of 19 molar teeth to be scheduled for immediate implant were se-lected to be treated with Zimmer dental implant system .17 of the 19 molar teeth were simultaneously operated with GBR tech-nique.The upper structure was repaired with Palladium PFM porcelain crown after the postoperative phase I of 4~6 months and postoperative phase II of 2 weeks.Results All the 19 dental implants were well combined and were stable in the follow-ing 12 months.Conclusion A good osseointegration is obtained in the molar teeth with Zimmer dental implant system .Cor-rectly dealing with the soft and hard tissues in the process of immediate implant of molar teeth shortens the period of treat-ment, and repairs the bone tissue defects around the original lost teeth and the surrounding gingival tissue form.The immedi-ate implant should be applied properly in the molar teeth .%目的:观察Zimmer种植体在后牙区即刻种植的临床效果。方法选择14例19颗后牙区即刻种植病例,采用Zimmer种植系统,其中17颗同时行GBR 技术,Ⅰ期术后4~6个月,Ⅱ期术后2周,上部结构采用钯金烤瓷冠修复。结果19颗种植体骨结合良好,追踪12个月,种植体稳存。结论 Zimmer 在后牙区采用即刻种植可以取得良好的骨结合。在后牙区即刻种植手术过程中,正确的软硬组织处理可以在缩短疗程的同时,良好的恢复了原缺失牙周围的骨组织缺损及周围牙龈组织形态。在后牙区即刻种植时,应选择恰当的适应症,避免盲目即刻种植。

  20. Dental Implant Surgery

    Science.gov (United States)

    ... here to find out more. Dental Implant Surgery Dental Implant Surgery Dental implant surgery is, of course, surgery, ... here to find out more. Dental Implant Surgery Dental Implant Surgery Dental implant surgery is, of course, surgery, ...