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Sample records for microbiologists providing detailed

  1. Interaction between the microbiology laboratory and clinician: what the microbiologist can provide

    DEFF Research Database (Denmark)

    Kolmos, H J

    1999-01-01

    The work of the clinical microbiologist comprises three major areas: diagnostic work in the laboratory, advice to clinicians about treatment of infected patients, and infection control. By clinical alertness, either from work in the laboratory or from clinical contacts, the microbiologist may...

  2. Importance of clinical microbiologists for U.S. healthcare infrastructure.

    Science.gov (United States)

    Carvalho, John

    2011-01-01

    Clinical microbiologists are highly skilled scientists within national hospitals and reference laboratories who diagnose patients with infections by emerging pathogens. Most advanced training for clinical microbiologists occurs at universities, where an individual can receive certification as a "Medical Laboratory Scientist" (MLS). Unfortunately, many MLS programs have closed in the United States and this has caused a shortage of clinical microbiologists at U.S. hospitals and reference laboratories. This paper explores the present crisis in MLS training and its ramifications for the emergence of antibiotic-resistant bacteria, the economics of hospitals, and the overall health of the nation, and provides resolutions for better public health policy with respect to MLS education.

  3. What is a microbiologist? A survey exploring the microbiology workforce.

    Science.gov (United States)

    Redfern, James; Verran, Joanna

    2015-12-01

    Microbiology has a long tradition of making inspirational, world-changing discovery. Microbiology now plays essential roles in many disciplines, leading to some microbiologists raising concern over the apparent loss of identity. An electronic survey was undertaken to capture the scientific identity (based on scientific discipline) of people for whom microbiology forms a part of their profession, in addition to information regarding their first degree (title, country and year in which the degree was completed) and the sector in which they currently work. A total of 447 responses were collected, representing 52 countries from which they gained their first degree. Biology was the most common first degree title (of 32 titles provided), while microbiologist was the most common scientific identity (of 26 identities provided). The data collected in this study gives a snapshot of the multidisciplinarity, specialism and evolving nature of the microbiology academic workforce. While the most common scientific identity chosen in this study was that of a microbiologist, it appears that the microbiological workforce is contributed to by a range of different disciplines, highlighting the cross-cutting, multidisciplined and essential role microbiology has within scientific endeavour. Perhaps, we should be less concerned with labels, and celebrate the success with which our discipline has delivered. © FEMS 2015. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  4. Interpretation of Blood Microbiology Results - Function of the Clinical Microbiologist.

    Science.gov (United States)

    Kristóf, Katalin; Pongrácz, Júlia

    2016-04-01

    The proper use and interpretation of blood microbiology results may be one of the most challenging and one of the most important functions of clinical microbiology laboratories. Effective implementation of this function requires careful consideration of specimen collection and processing, pathogen detection techniques, and prompt and precise reporting of identification and susceptibility results. The responsibility of the treating physician is proper formulation of the analytical request and to provide the laboratory with complete and precise patient information, which are inevitable prerequisites of a proper testing and interpretation. The clinical microbiologist can offer advice concerning the differential diagnosis, sampling techniques and detection methods to facilitate diagnosis. Rapid detection methods are essential, since the sooner a pathogen is detected, the better chance the patient has of getting cured. Besides the gold-standard blood culture technique, microbiologic methods that decrease the time in obtaining a relevant result are more and more utilized today. In the case of certain pathogens, the pathogen can be identified directly from the blood culture bottle after propagation with serological or automated/semi-automated systems or molecular methods or with MALDI-TOF MS (matrix-assisted laser desorption-ionization time of flight mass spectrometry). Molecular biology methods are also suitable for the rapid detection and identification of pathogens from aseptically collected blood samples. Another important duty of the microbiology laboratory is to notify the treating physician immediately about all relevant information if a positive sample is detected. The clinical microbiologist may provide important guidance regarding the clinical significance of blood isolates, since one-third to one-half of blood culture isolates are contaminants or isolates of unknown clinical significance. To fully exploit the benefits of blood culture and other (non- culture

  5. Socializing, networking and development: a report from the second 'Young Microbiologists Symposium on Microbe Signalling, Organization and Pathogenesis'.

    Science.gov (United States)

    Caly, Delphine L; Coulthurst, Sarah J; Geoghegan, Joan A; Malone, Jacob G; Ryan, Robert P

    2012-11-01

    In mid-June, the second Young Microbiologists Symposium took place under the broad title of 'Microbe signalling, organization and pathogenesis' on the picturesque campus of University College Cork, Ireland. The symposium attracted 150 microbiologists from 15 different countries. The key feature of this meeting was that it was specifically aimed at providing a platform for junior scientists to present their work to a broad audience. The meeting was principally supported by Science Foundation Ireland with further backing from the Society for General Microbiology, the American Society for Microbiology and the European Molecular Biology Organization. Sessions focused on microbial gene expression, biogenesis, pathogenicity and host interaction. In this MicroMeeting report, we highlight some of the most significant advances and exciting developments reported during various talks and poster presentations given by the young and talented microbiologists. © 2012 Blackwell Publishing Ltd.

  6. Sequential antimicrobial therapy: comparison of the views of microbiologists and pharmacists.

    Science.gov (United States)

    Smyth, E T; Tillotson, G S

    1998-07-01

    Sequential antimicrobial therapy (SAT) is arousing keen interest in microbiologists and pharmacists. In an attempt to obtain information from these groups regarding the use of SAT in hospitals, an anonymized postal survey was carried out. A SAT questionnaire was circulated to consultant medical microbiologists, clinical microbiologists, and heads of pharmacy departments within the British Isles. Four hundred and forty-seven microbiologists and pharmacists returned completed questionnaires, giving a response rate of 29%. Just over half of medical microbiologists (MM) and pharmacists (PH) indicated that SAT was used in their institution in respiratory medicine, geriatrics, surgery and, significantly, to a lesser degree in paediatrics. The most common infections treated were pneumonia, bronchitis and wound infection. However, there were significant differences between MM and PH, with MM favouring greater use of SAT in peritonitis (P=0.03), septicaemia (PUTI) (P<0.01), and PH favouring use in bronchitis (P<0.01). The ability to take oral fluids or a recognition of no potential absorption problems were key criteria in the decision process leading to the institution of SAT by MM and PH. Significantly more MM favoured employing criteria such as temperature <38 degrees C (P<0.01), no requirement for high tissue concentrations (P=0.02) and evidence of response to i.v. antimicrobial therapy (P<0.01) than PH. The most frequently "switched" antimicrobials were metronidazole, ciprofloxacin and co-amoxiclav. There were more than five times as many MM reporting the use of clindamycin than PH (P<0.01), whereas nearly twice as many PH cited use of cefuroxime (P<0.01). Of those hospitals not employing SAT, most MM and PH concurred that the commonest reason to institute SAT was financial, followed by convenience to patients and staff. However, more PH than MM indicated that protocols (P<0.01) and a reduction in i.v. complications (P<0.01) were important to them. In promoting SAT, MM

  7. Where do out-of-hours calls to a consultant microbiologist come from?

    LENUS (Irish Health Repository)

    Humphreys, H

    2009-08-01

    There is little in the literature about out-of-hours calls to medical microbiologists. The calls taken by a consultant medical microbiologist over a five-year period in an Irish tertiary referral hospital were reviewed. Excluding calls on weekend mornings and significant evening positive blood cultures, the mean annual number of calls on a one-in-four rota was 89 (range 70-111). Over 90% of calls were received before midnight and 51% were from specialist registrars. Medical specialties, neurosurgery and intensive care were the most common departments seeking advice. Two-thirds of calls related to the management of an individual patient, but advice on infection prevention and control is increasingly requested. Calls out-of-hours are not insignificant but little is known about how these vary between hospitals and what contribution they make to patient care.

  8. Status of women microbiologists.

    Science.gov (United States)

    Kashket, E R; Robbins, M L; Leive, L; Huang, A S

    1974-02-08

    The general picture that emerges from this study is that the woman microbiologist, upon entering the professional job market, faces (i) slower advancement; (ii) restricted extramural recognition; and (iii) fewer positions of a supervisory or administrative nature, when compared to men. Most striking is the salary differential, which increases with increasing educational level, with increasing rank, and with increasing seniority. From the beginning of her professional training, the woman microbiologist feels handicapped by lack of encouragement and proper role models. She generally receives little advice regarding her professional future and rarely feels pushed to take the most challenging position. Should she be married, she feels that her mobility is severely restricted. Even though the subjective nature of these feelings may be interpreted as projections of failure, subtle inducements for women to stay at lower levels may well exist, in addition to more objective measurements, such as lower salary levels and slower professional advancement. Despite these handicaps, professional women continue to work. As a group, they work for the same reasons that men do, they work as long and as hard as men do, and they remain at their positions as long as men do. Women and men rate themselves equally as to job performance, degree of independence, and publication rate. On the basis of this study, it should not be surprising that women professionals are less visible than men and that only a small proportion of women become what is considered successful by the usual external criteria. If women were to receive continued encouragement, scientific contact, and professional recognition at each stage of their professional lives, they would undoubtedly become more visible. The lack of encouragement and selfconfidence leading to isolation, which then leads to lack of recognition, is a vicious circle that must be broken for the woman professional. This can be done most easily for the

  9. Bioethics, bioweapons and the microbiologist.

    Science.gov (United States)

    Anaya-Velázquez, Fernando

    2002-01-01

    The analysis of behavior of man in the field of biology is carried out through bioethics, considered the science of the survival. In the microbiology, there are numerous discoveries related with pathogenic microorganisms, including those that can be used as weapons in a biological war or in an attack considered bioterrorism. The scientist involved in microbiology can participate with his knowledge in the development and improvement of bioweapons, however from the point of view of bioethics it is not acceptable that he works in an investigation related with these topics, because the defense research can evolve in offensive one. The war is an antisurvival activity, therefore it is not acceptable. In the same way, the biological weapons composed with virus, fungi or alive bacteria, or with toxins from them, neither they are morally accepted. After the terrorist attacks with anthrax in the United States in 2001, the world scientific community in the field of microbiology should show against the use of the microorganisms like bioweapons, at the time of promoting the idea that the responsible use for the microorganisms is a moral imperative for all microbiologists around the world, since the biological weapons are a threat for the human life.

  10. Comparing and Evaluating Metagenome Assembly Tools from a Microbiologist's Perspective - Not Only Size Matters!

    Directory of Open Access Journals (Sweden)

    John Vollmers

    Full Text Available With the constant improvement in cost-efficiency and quality of Next Generation Sequencing technologies, shotgun-sequencing approaches -such as metagenomics- have nowadays become the methods of choice for studying and classifying microorganisms from various habitats. The production of data has dramatically increased over the past years and processing and analysis steps are becoming more and more of a bottleneck. Limiting factors are partly the availability of computational resources, but mainly the bioinformatics expertise in establishing and applying appropriate processing and analysis pipelines. Fortunately, a large diversity of specialized software tools is nowadays available. Nevertheless, choosing the most appropriate methods for answering specific biological questions can be rather challenging, especially for non-bioinformaticians. In order to provide a comprehensive overview and guide for the microbiological scientific community, we assessed the most common and freely available metagenome assembly tools with respect to their output statistics, their sensitivity for low abundant community members and variability in resulting community profiles as well as their ease-of-use. In contrast to the highly anticipated "Critical Assessment of Metagenomic Interpretation" (CAMI challenge, which uses general mock community-based assembler comparison we here tested assemblers on real Illumina metagenome sequencing data from natural communities of varying complexity sampled from forest soil and algal biofilms. Our observations clearly demonstrate that different assembly tools can prove optimal, depending on the sample type, available computational resources and, most importantly, the specific research goal. In addition, we present detailed descriptions of the underlying principles and pitfalls of publically available assembly tools from a microbiologist's perspective, and provide guidance regarding the user-friendliness, sensitivity and reliability of

  11. A survey of time management and particular tasks undertaken by consultant microbiologists in the UK.

    Science.gov (United States)

    Riordan, Terry; Cartwright, Keith; Cunningham, Richard; Logan, Margaret; Wright, Paul

    2007-05-01

    Medical microbiology practice encompasses a diverse range of activities. Consultant medical microbiologists (CMMs) attribute widely differing priorities to, and spend differing proportions of time on various components of the job. To obtain a professional consensus on what are high-priority and low-priority activities, and to identify the time spent on low-priority activities. National survey. Many respondents felt that time spent on report authorisation and telephoning of results was excessive, whereas time spent on ward-based work was inadequate. Timesaving could also be achieved through better prioritisation of infection-control activities. CMMs should apportion their time at work focusing on high-priority activities identified through professional consensus.

  12. A survey of time management and particular tasks undertaken by consultant microbiologists in the UK

    Science.gov (United States)

    Riordan, Terry; Cartwright, Keith; Cunningham, Richard; Logan, Margaret; Wright, Paul

    2007-01-01

    Background Medical microbiology practice encompasses a diverse range of activities. Consultant medical microbiologists (CMMs) attribute widely differing priorities to, and spend differing proportions of time on various components of the job. Aim To obtain a professional consensus on what are high‐priority and low‐priority activities, and to identify the time spent on low‐priority activities. Method National survey. Results Many respondents felt that time spent on report authorisation and telephoning of results was excessive, whereas time spent on ward‐based work was inadequate. Timesaving could also be achieved through better prioritisation of infection‐control activities. Conclusion CMMs should apportion their time at work focusing on high‐priority activities identified through professional consensus. PMID:16714398

  13. Metagenomes provide valuable comparative information on soil microeukaryotes

    DEFF Research Database (Denmark)

    Jacquiod, Samuel Jehan Auguste; Stenbæk, Jonas; Santos, Susana

    2016-01-01

    has been identified. Our analyses suggest that publicly available metagenome data can provide valuable information on soil microeukaryotes for comparative purposes when handled appropriately, complementing the current view provided by ribosomal amplicon sequencing methods......., providing microbiologists with substantial amounts of accessible information. We took advantage of public metagenomes in order to investigate microeukaryote communities in a well characterized grassland soil. The data gathered allowed the evaluation of several factors impacting the community structure......, including the DNA extraction method, the database choice and also the annotation procedure. While most studies on soil microeukaryotes are based on sequencing of PCR-amplified taxonomic markers (18S rRNA genes, ITS regions), this work represents, to our knowledge, the first report based solely...

  14. [Contribution of microbiologists of Kirov City to development of penicillin and streptomycin production processes (70 years since development of technology for submerged production of first domestic antibiotics)].

    Science.gov (United States)

    Bakulin, M K; Tumanov, A S; Bakulin, V M; Kalininskiĭ, V B

    2014-01-01

    The publication is concerned with development of the technological processes for submered production of the first domestic antibiotics 70 years age. The literature data on the contribution of the microbiologists of the Kirov City and mainly the workers of the Red Army Research Institute of Epidemiology and Hygiene (nowadays Central Research Institute No. 48 of the Ministry of Defense of the Russian Federation, Kirov), to development of the manufacture processes for production of penicillin and streptomycin are reviewed.

  15. Broad-range (pan) Salmonella and Salmonella serotype typhi-specific real-time PCR assays: potential tools for the clinical microbiologist.

    Science.gov (United States)

    Farrell, John J; Doyle, Laura J; Addison, Rachel M; Reller, L Barth; Hall, Geraldine S; Procop, Gary W

    2005-03-01

    We describe broad-range salmonellae (ie, Salmonella) and Salmonella serotype Typhi-specific LightCycler (Roche Diagnostics, Indianapolis, IN) real-time polymerase chain reaction assays. We validated these with a battery of 280 bacteria, 108 of which were salmonellae representing 20 serotypes. In addition, 298 isolates from 170 clinical specimens that were suspected to possibly represent Salmonella were tested with the pan- Salmonella assay. Finally, the pan-Salmonella assay also was used to test DNA extracts from 101 archived, frozen stool specimens, 55 of which were culture-positive for salmonellae. Both assays were 100% sensitive and specific when cultured isolates of the battery were tested. The pan- Salmonella assay also characterized correctly all salmonellae on the primary isolation agar and was 96% sensitive (53/55) and 96% specific (49/51) when nucleic acid extracts from direct stool specimens were tested. These assays represent potential tools the clinical microbiologist could use to screen suspect isolates or stool specimens for Salmonella.

  16. Inequality dynamics in the workplace among microbiologists and infectious disease specialists: a qualitative study in five European countries.

    Science.gov (United States)

    Huttner, A; Cacace, M; d'Andrea, L; Skevaki, C; Otelea, D; Pugliese, F; Tacconelli, E

    2017-05-01

    To explore the social, cultural, psychological and organizational factors associated with inequality in the workplace among clinical microbiologists (CM) and infectious disease (ID) specialists in European hospitals. We analysed data from 52 interviews and five focus groups involving 82 CM/ID specialists selected from university, research or community hospitals in five countries, one each in Northern, Western, Eastern, Southeastern and Southwestern Europe. The 80 hours of recordings were transcribed, and the anonymous database coding process was cross-checked iteratively by six researchers. Inequality affects all the institutions in all the countries we looked at, denying or reducing access to professional assets with intensity and form that vary largely according to the cultural and organizational context. Discrimination is generally not explicit and uses disrespectful microbehaviours that are hard to respond to when they occur. Inequality affected also loans, distribution of research funds and gender and country representation in boards and conference faculty. Parenthood has a major impact on women's careers, as women are still mainly responsible for family care. Responses to discrimination range from reactive to surrender strategies. Our study offers an effective model for diagnosing discriminatory behaviours in a medical professional setting. Knowledge of inequality's drivers could help national ID/CM societies in collaboration with major European stakeholders to further reduce such discrimination. The effect of discrimination on the quality of healthcare in Europe needs further exploration. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

  17. Great Basin land managers provide detailed feedback about usefulness of two climate information web applications

    Directory of Open Access Journals (Sweden)

    Chad Zanocco

    Full Text Available Land managers in the Great Basin are working to maintain or restore sagebrush ecosystems as climate change exacerbates existing threats. Web applications delivering climate change and climate impacts information have the potential to assist their efforts. Although many web applications containing climate information currently exist, few have been co-produced with land managers or have incorporated information specifically focused on land managers’ needs. Through surveys and interviews, we gathered detailed feedback from federal, state, and tribal sagebrush land managers in the Great Basin on climate information web applications targeting land management. We found that a managers are searching for weather and climate information they can incorporate into their current management strategies and plans; b they are willing to be educated on how to find and understand climate related web applications; c both field and administrative-type managers want data for timescales ranging from seasonal to decadal; d managers want multiple levels of climate information, from simple summaries, to detailed descriptions accessible through the application; and e managers are interested in applications that evaluate uncertainty and provide projected climate impacts. Keywords: Great Basin, Sagebrush, Land management, Climate change, Web application, Co-production

  18. Academic Detailing with Provider Audit and Feedback Improve Prescribing Quality for Older Veterans.

    Science.gov (United States)

    Vandenberg, Ann E; Echt, Katharina V; Kemp, Lawanda; McGwin, Gerald; Perkins, Molly M; Mirk, Anna K

    2018-03-01

    Suboptimal prescribing persists as a driver of poor quality care of older veterans and is associated with risk of hospitalization and emergency department visits. We adapted a successful medication management model, Integrated Management and Polypharmacy Review of Vulnerable Elders (IMPROVE), from an urban geriatric specialty clinic to rural community-based clinics that deliver primary care. The goals were to promote prescribing quality and safety for older adults, including reduced prescribing of potentially inappropriate medications (PIMs). We augmented the original model, which involved a pharmacist-led, one-on-one medication review with high-risk older veterans, to provide rural primary care providers (PCPs) and pharmacists with educational outreach through academic detailing and tools to support safe geriatric prescribing practices, as well as individual audit and feedback on prescribing practice and confidential peer benchmarking. Twenty PCPs and 4 pharmacists at 4 rural Georgia community-based outpatient clinics participated. More than 7,000 older veterans were seen in more than 20,000 PCP encounters during the 14-month intervention period. Implementation of the IMPROVE intervention reduced PIM prescribing incidence from 9.6 new medications per 100 encounters during baseline to 8.7 after the intervention (P = .009). IMPROVE reduced PIM prevalence (proportion of encounters involving veterans who were taking at least 1 PIM) from 22.6% to 16.7% (P < .001). These approaches were effective in reducing PIMs prescribed to older veterans in a rural setting and constitute a feasible model for disseminating geriatric best practices to the primary care setting. © 2018, Copyright the Authors Journal compilation © 2018, The American Geriatrics Society.

  19. Providing detailed information about latent tuberculosis and compliance with the PPD test among healthcare workers in Israel: A randomized controlled study

    Directory of Open Access Journals (Sweden)

    Danielle Taubman

    2013-12-01

    Conclusions: Compliance for latent TB screening is low among HCWs in northeastern Israel. Providing detailed information about latent TB was not associated with increased test compliance. Understanding existing disparities in screening rates and potential barriers to latent TB screening among HCWs is important in order to move forward and successfully increase screening rates.

  20. Detailed Facility Report Data Dictionary | ECHO | US EPA

    Science.gov (United States)

    The Detailed Facility Report Data Dictionary provides users with a list of the variables and definitions that have been incorporated into the Detailed Facility Report. The Detailed Facility Report provides a concise enforcement and compliance history for a facility.

  1. Methodological Details and Full Bibliography

    Data.gov (United States)

    U.S. Environmental Protection Agency — This dataset has several components, The first part describes fully our literature review, providing details not included in the text. The second part provides all...

  2. Using public health detailing and a family-centered ecological approach to promote patient-provider-parent action for reducing childhood obesity.

    Science.gov (United States)

    Sealy, Yvette M; Zarcadoolas, Christina; Dresser, Michelle; Wedemeyer, Laura; Short, Leslie; Silver, Lynn

    2012-04-01

    This paper describes the research and development of the Obesity in Children Action Kit, a paper-based chronic disease management tool of the Public Health Detailing Program (PHD) at the New York City (NYC) Department of Health and Mental Hygiene (DOHMH). It also describes PHD's process for developing the Obesity in Children detailing campaign (targeting healthcare providers working with children aged 2-18) and its results, during which the Action Kit materials were a focal point. The campaign goals were to impact healthcare provider clinical behaviors, improve the health literacy of parents and children, instigate patient-provider-parent dialogue, and change family practices to prevent obesity. Qualitative research methods consisted of healthcare provider in-depth interviews and parent focus groups to aid campaign development. Evaluation of the Obesity in Children campaign included self-reported data on uptake and usage of clinical tools and action steps of matched assessments from 237 healthcare provider initial and follow-up visits, material stock counts, and DOHMH representative qualitative visit excerpts. Key themes identified in parent focus groups were concerns about childhood diabetes and high blood pressure, awareness of cultural pressure and our "supersize" culture, frustration with family communication around overweight and obesity, lack of knowledge about food quality and portion size, economic pressures, and the availability of healthy and nutritious foods. During the Obesity in Children campaign, six representatives reached 161 practices with 1,588 one-on-one interactions, and an additional 461 contacts were made through group presentations. After these interactions, there was a significant increase in the percentage of physicians self-reported use of key recommended practices: Use of BMI percentile-for-age to assess for overweight or obesity at every visit increased from 77% to 88% (p families to set realistic goals increased from 64% to 86% (p

  3. E-detailing: information technology applied to pharmaceutical detailing.

    Science.gov (United States)

    Montoya, Isaac D

    2008-11-01

    E-detailing can be best described as the use of information technology in the field of pharmaceutical detailing. It is becoming highly popular among pharmaceutical companies because it maximizes the time of the sales force, cuts down the cost of detailing and increases physician prescribing. Thus, the application of information technology is proving to be beneficial to both physicians and pharmaceutical companies. When e-detailing was introduced in 1996, it was limited to the US; however, numerous other countries soon adopted this novel approach to detailing and now it is popular in many developed nations. The objective of this paper is to demonstrate the rapid growth of e-detailing in the field of pharmaceutical marketing. A review of e-detailing literature was conducted in addition to personal conversations with physicians. E-detailing has the potential to reduce marketing costs, increase accessibility to physicians and offer many of the advantages of face-to-face detailing. E-detailing is gaining acceptance among physicians because they can access the information of a pharmaceutical product at their own time and convenience. However, the drug safety aspect of e-detailing has not been examined and e-detailing remains a supplement to traditional detailing and is not yet a replacement to it.

  4. 41 CFR 102-75.1225 - What details are provided in the “Notice of Availability”?

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What details are... Management Federal Property Management Regulations System (Continued) FEDERAL MANAGEMENT REGULATION REAL... information, and a date by which an interested Federal agency must respond in writing to indicate a definite...

  5. Multiple-endpoint assay provides a detailed mechanistic view of responses to herbicide exposure in Chlamydomonas reinhardtii

    International Nuclear Information System (INIS)

    Nestler, Holger; Groh, Ksenia J.; Schönenberger, René; Behra, Renata; Schirmer, Kristin; Eggen, Rik I.L.; Suter, Marc J.-F.

    2012-01-01

    The release of herbicides into the aquatic environment raises concerns about potential detrimental effects on ecologically important non-target species, such as unicellular algae, necessitating ecotoxicological risk assessment. Algal toxicity tests based on growth, a commonly assessed endpoint, are integrative, and hence do not provide information about underlying toxic mechanisms and effects. This limitation may be overcome by measuring more specific biochemical and physiological endpoints. In the present work, we developed and applied a novel multiple-endpoint assay, and analyzed the effects of the herbicides paraquat, diuron and norflurazon, each representing a specific mechanism of toxic action, on the single celled green alga Chlamydomonas reinhardtii. The endpoints added to assessment of growth were pigment content, maximum and effective photosystem II quantum yield, ATP content, esterase and oxidative activity. All parameters were measured at 2, 6 and 24 h of exposure, except for growth and pigment content, which were determined after 6 and 24 h only. Effective concentrations causing 50% of response (EC50s) and lowest observable effect concentrations (LOECs) were determined for all endpoints and exposure durations where possible. The assay provided a detailed picture of the concentration- and time-dependent development of effects elicited by the analyzed herbicides, thus improving the understanding of the underlying toxic mechanisms. Furthermore, the response patterns were unique to the respective herbicide and reflected the different mechanisms of toxicity. The comparison of the endpoint responses and sensitivities revealed that several physiological and biochemical parameters reacted earlier or stronger to disturbances than growth. Overall, the presented multiple-endpoint assay constitutes a promising basis for investigating stressor and toxicant effects in green algae.

  6. Multiple-endpoint assay provides a detailed mechanistic view of responses to herbicide exposure in Chlamydomonas reinhardtii

    Energy Technology Data Exchange (ETDEWEB)

    Nestler, Holger [Eawag, Swiss Federal Institute of Aquatic Science and Technology, Ueberlandstrasse 133, 8600 Duebendorf (Switzerland); ETH Zurich, Swiss Federal Institute of Technology, Institute of Biogeochemistry and Pollutant Dynamics, Universitaetstrasse 16, 8092 Zurich (Switzerland); Groh, Ksenia J.; Schoenenberger, Rene; Behra, Renata [Eawag, Swiss Federal Institute of Aquatic Science and Technology, Ueberlandstrasse 133, 8600 Duebendorf (Switzerland); Schirmer, Kristin [Eawag, Swiss Federal Institute of Aquatic Science and Technology, Ueberlandstrasse 133, 8600 Duebendorf (Switzerland); ETH Zurich, Swiss Federal Institute of Technology, Institute of Biogeochemistry and Pollutant Dynamics, Universitaetstrasse 16, 8092 Zurich (Switzerland); EPF Lausanne, School of Architecture, Civil and Environmental Engineering, 1015 Lausanne (Switzerland); Eggen, Rik I.L. [Eawag, Swiss Federal Institute of Aquatic Science and Technology, Ueberlandstrasse 133, 8600 Duebendorf (Switzerland); ETH Zurich, Swiss Federal Institute of Technology, Institute of Biogeochemistry and Pollutant Dynamics, Universitaetstrasse 16, 8092 Zurich (Switzerland); Suter, Marc J.-F., E-mail: suter@eawag.ch [Eawag, Swiss Federal Institute of Aquatic Science and Technology, Ueberlandstrasse 133, 8600 Duebendorf (Switzerland); ETH Zurich, Swiss Federal Institute of Technology, Institute of Biogeochemistry and Pollutant Dynamics, Universitaetstrasse 16, 8092 Zurich (Switzerland)

    2012-04-15

    The release of herbicides into the aquatic environment raises concerns about potential detrimental effects on ecologically important non-target species, such as unicellular algae, necessitating ecotoxicological risk assessment. Algal toxicity tests based on growth, a commonly assessed endpoint, are integrative, and hence do not provide information about underlying toxic mechanisms and effects. This limitation may be overcome by measuring more specific biochemical and physiological endpoints. In the present work, we developed and applied a novel multiple-endpoint assay, and analyzed the effects of the herbicides paraquat, diuron and norflurazon, each representing a specific mechanism of toxic action, on the single celled green alga Chlamydomonas reinhardtii. The endpoints added to assessment of growth were pigment content, maximum and effective photosystem II quantum yield, ATP content, esterase and oxidative activity. All parameters were measured at 2, 6 and 24 h of exposure, except for growth and pigment content, which were determined after 6 and 24 h only. Effective concentrations causing 50% of response (EC50s) and lowest observable effect concentrations (LOECs) were determined for all endpoints and exposure durations where possible. The assay provided a detailed picture of the concentration- and time-dependent development of effects elicited by the analyzed herbicides, thus improving the understanding of the underlying toxic mechanisms. Furthermore, the response patterns were unique to the respective herbicide and reflected the different mechanisms of toxicity. The comparison of the endpoint responses and sensitivities revealed that several physiological and biochemical parameters reacted earlier or stronger to disturbances than growth. Overall, the presented multiple-endpoint assay constitutes a promising basis for investigating stressor and toxicant effects in green algae.

  7. Academic detailing.

    Science.gov (United States)

    Shankar, P R; Jha, N; Piryani, R M; Bajracharya, O; Shrestha, R; Thapa, H S

    2010-01-01

    There are a number of sources available to prescribers to stay up to date about medicines. Prescribers in rural areas in developing countries however, may not able to access some of them. Interventions to improve prescribing can be educational, managerial, and regulatory or use a mix of strategies. Detailing by the pharmaceutical industry is widespread. Academic detailing (AD) has been classically seen as a form of continuing medical education in which a trained health professional such as a physician or pharmacist visits physicians in their offices to provide evidence-based information. Face-to-face sessions, preferably on an individual basis, clear educational and behavioural objectives, establishing credibility with respect to objectivity, stimulating physician interaction, use of concise graphic educational materials, highlighting key messages, and when possible, providing positive reinforcement of improved practices in follow-up visits can increase success of AD initiatives. AD is common in developed countries and certain examples have been cited in this review. In developing countries the authors have come across reports of AD in Pakistan, Sudan, Argentina and Uruguay, Bihar state in India, Zambia, Cuba, Indonesia and Mexico. AD had a consistent, small but potentially significant impact on prescribing practices. AD has much less resources at its command compared to the efforts by the industry. Steps have to be taken to formally start AD in Nepal and there may be specific hindering factors similar to those in other developing nations.

  8. CLIMB (the Cloud Infrastructure for Microbial Bioinformatics): an online resource for the medical microbiology community.

    Science.gov (United States)

    Connor, Thomas R; Loman, Nicholas J; Thompson, Simon; Smith, Andy; Southgate, Joel; Poplawski, Radoslaw; Bull, Matthew J; Richardson, Emily; Ismail, Matthew; Thompson, Simon Elwood-; Kitchen, Christine; Guest, Martyn; Bakke, Marius; Sheppard, Samuel K; Pallen, Mark J

    2016-09-01

    The increasing availability and decreasing cost of high-throughput sequencing has transformed academic medical microbiology, delivering an explosion in available genomes while also driving advances in bioinformatics. However, many microbiologists are unable to exploit the resulting large genomics datasets because they do not have access to relevant computational resources and to an appropriate bioinformatics infrastructure. Here, we present the Cloud Infrastructure for Microbial Bioinformatics (CLIMB) facility, a shared computing infrastructure that has been designed from the ground up to provide an environment where microbiologists can share and reuse methods and data.

  9. Influences on physicians' adoption of electronic detailing (e-detailing).

    Science.gov (United States)

    Alkhateeb, Fadi M; Doucette, William R

    2009-01-01

    E-detailing means using digital technology: internet, video conferencing and interactive voice response. There are two types of e-detailing: interactive (virtual) and video. Currently, little is known about what factors influence physicians' adoption of e-detailing. The objectives of this study were to test a model of physicians' adoption of e-detailing and to describe physicians using e-detailing. A mail survey was sent to a random sample of 2000 physicians practicing in Iowa. Binomial logistic regression was used to test the model of influences on physician adoption of e-detailing. On the basis of Rogers' model of adoption, the independent variables included relative advantage, compatibility, complexity, peer influence, attitudes, years in practice, presence of restrictive access to traditional detailing, type of specialty, academic affiliation, type of practice setting and control variables. A total of 671 responses were received giving a response rate of 34.7%. A total of 141 physicians (21.0%) reported using of e-detailing. The overall adoption model for using either type of e-detailing was found to be significant. Relative advantage, peer influence, attitudes, type of specialty, presence of restrictive access and years of practice had significant influences on physician adoption of e-detailing. The model of adoption of innovation is useful to explain physicians' adoption of e-detailing.

  10. The devil is in the detail: children's recollection of details about their prior experiences.

    Science.gov (United States)

    Strange, Deryn; Hayne, Harlene

    2013-01-01

    Adults sometimes report highly specific details of childhood events, including the weather, what they or others were wearing, as well as information about what they or others said or were thinking at the time. When these details are reported in the course of research they shape our theories of memory development; when they are reported in a criminal trial they influence jurors' evaluation of guilt or innocence. The key question is whether these details were encoded at the time the event took place or have been added after the fact. We addressed this question prospectively by examining the memory accounts of children. In Experiment 1 we coded the reports of 5- to 6-year-olds and 9- to 10-year-olds who had experienced a unique event. We found that spontaneous mentions of these specific details were exceedingly rare. In Experiment 2 we questioned additional children about a similar event using specific questions to extract those details. We found that 9- to 10-year-olds were able to accurately answer, while 5- to 6-year-olds had considerable difficulty. Moreover, when the younger children did respond they provided generic, forensically inadequate, information. These data have important implications for the courtroom and for current theories of memory development and childhood amnesia.

  11. The detail is dead - long live the detail!

    DEFF Research Database (Denmark)

    Larsen, Steen Nepper; Dalgaard, Kim; Kerstens, Vencent

    2018-01-01

    architecture when we look into architectural history. Too classic examples are; Adolf Loos who provoked already in 1908 with his statement; "Ornament and Crime", which contested the unconscious decorations of contemporary architects. Similarly, referring to the little need for superfluous detailing; "Less...... not change the fact that it is more important than ever to bring this 'small' architectural world to attention. Today, the construction industry is dictated by an economic management that does not leave much room for thorough studies of architectural details or visionary experiments. Today's more efficient......_Delft about the Symposium; "The Detail is Dead - Long Live the Detail". For this occasion a number of leading Danish and Northern European architects, researchers and companies were invited to discuss and suggest their 'architectural detail' and the challenges they face in today's construction. This book...

  12. Regulation No. 56/2006 Coll. of the Nuclear Regulatory Authority of the Slovak Republic dated as of January 12, 2006 on details concerning requirements for quality system documentation of authorisation holder, as well as details concerning quality requirements for nuclear installations, details concerning quality requirements for classified equipment and details concerning the scope of their approval

    International Nuclear Information System (INIS)

    2006-01-01

    This Regulation provides details of the requirements for quality system documentation holder, details of the quality requirements for nuclear installations, details concerning quality requirements for classified equipment and details of the scope of their approval. This Regulation came into force on March 1, 2006.

  13. Space Telecommunications Radio System (STRS) Architecture, Tutorial Part 2 - Detailed

    Science.gov (United States)

    Handler, Louis

    2014-01-01

    The STRS architecture detail presentation presents each requirement in the STRS Architecture Standard with some examples and supporting information. The purpose is to give a platform provider, application provider, or application integrator a better, more detailed understanding of the STRS Architecture Standard and its use.

  14. Author Details

    African Journals Online (AJOL)

    Details PDF · Vol 22, No 2 (1999) - Articles Vegetation under different tree species in Acacia woodland in the Rift Valley of Ethiopia Details PDF · Vol 22, No 2 (1999) - Articles Preliminary evaluation of Phytomyza orobanchia (Diptera: Agromyzidae) as a controller of Orobanche spp in Ethiopia Details PDF. ISSN: 2520–7997.

  15. Microbiological research and development for the food industry

    National Research Council Canada - National Science Library

    Taormina, Peter J

    2013-01-01

    "This book serves as a primer and reference for industrial food microbiologists who typically gain the information provided through on-the-job experience or from a consultant instead of in the classroom...

  16. Molecular Details of Olfactomedin Domains Provide Pathway to Structure-Function Studies.

    Directory of Open Access Journals (Sweden)

    Shannon E Hill

    detailed functional characterization of these biomedically important protein domains.

  17. Author Details

    African Journals Online (AJOL)

    Author Details. Journal Home > Advanced Search > Author Details. Log in or Register to get access to full text downloads. ... An algorithm to retrieve Land Surface Temperature using Landsat-8 Dataset Abstract PDF. ISSN: 2225-8531.

  18. Main: Clone Detail [KOME

    Lifescience Database Archive (English)

    Full Text Available Clone Detail Mapping Pseudomolecule data detail Detail information Mapping to the T...IGR japonica Pseudomolecules kome_mapping_pseudomolecule_data_detail.zip kome_mapping_pseudomolecule_data_detail ...

  19. Author Details

    African Journals Online (AJOL)

    PROMOTING ACCESS TO AFRICAN RESEARCH. AFRICAN JOURNALS ONLINE (AJOL) · Journals · Advanced Search · USING AJOL · RESOURCES. Author Details. Journal Home > Advanced Search > Author Details. Log in or Register to get access to full text downloads.

  20. A model for determining when an analysis contains sufficient detail to provide adequate NEPA coverage for a proposed action

    International Nuclear Information System (INIS)

    Eccleston, C.H.

    1994-11-01

    Neither the National Environmental Policy Act (NEPA) nor its subsequent regulations provide substantive guidance for determining the Level of detail, discussion, and analysis that is sufficient to adequately cover a proposed action. Yet, decisionmakers are routinely confronted with the problem of making such determinations. Experience has shown that no two decisionmakers are Likely to completely agree on the amount of discussion that is sufficient to adequately cover a proposed action. one decisionmaker may determine that a certain Level of analysis is adequate, while another may conclude the exact opposite. Achieving a consensus within the agency and among the public can be problematic. Lacking definitive guidance, decisionmakers and critics alike may point to a universe of potential factors as the basis for defending their claim that an action is or is not adequately covered. Experience indicates that assertions are often based on ambiguous opinions that can be neither proved nor disproved. Lack of definitive guidance slows the decisionmaking process and can result in project delays. Furthermore, it can also Lead to inconsistencies in decisionmaking, inappropriate Levels of NEPA documentation, and increased risk of a project being challenged for inadequate coverage. A more systematic and less subjective approach for making such determinations is obviously needed. A paradigm for reducing the degree of subjectivity inherent in such decisions is presented in the following paper. The model is specifically designed to expedite the decisionmaking process by providing a systematic approach for making these determination. In many cases, agencies may find that using this model can reduce the analysis and size of NEPA documents

  1. Author Details

    African Journals Online (AJOL)

    An Overview of Africa's Marine Resources: Their Utilization and Sustainable Management Details · Vol 12, No 3 (2000) - Articles EDITORIAL Ganoderma Lucidum - Paramount among Medicinal Mushrooms. Details · Vol 15, No 3 (2003) - Articles Editorial: Africa's Mushrooms: A neglected bioresource whose time has come

  2. Author Details

    African Journals Online (AJOL)

    Petrology of the Cenomanian Upper Member of the Mamfe Embayment, southwestern Cameroon Details · Vol 38, No 1 (2002) - Articles Sequence stratigraphy of Iso field, western onshore Niger Delta, Nigeria Details · Vol 39, No 2 (2003) - Articles Preliminary studies on the lithostratigraphy and depositional environment of ...

  3. Wooden houses in detail. Holzhaeuser im Detail

    Energy Technology Data Exchange (ETDEWEB)

    Ruske, W. (ed.)

    1986-01-01

    Under the serial title 'Planning and construction of wooden houses', WEKA will publish a number of books of which this is the first. Details of design and construction are presented, e.g.: Details of modern one-family houses; Fundamentals of design and hints for planning of wooden houses and compact wooden structures; Constructional ecology, wood protection, thermal insulation, sound insulation; Modular systems for domestic buildings; The 'bookshelf-type' house at the Berlin International Construction Exhibition (IBA); Experience with do-it-yourself systems. With 439 figs.

  4. Author Details

    African Journals Online (AJOL)

    Author Details. Journal Home > Advanced Search > Author Details. Log in or Register to get access to full text downloads. ... Singh, J. Vol 3, No 2 (2011) - Articles Plane waves in a rotating generalized thermo-elastic solid with voids. Abstract PDF. ISSN: 2141-2839. AJOL African Journals Online. HOW TO USE AJOL.

  5. Author Details

    African Journals Online (AJOL)

    Author Details. Journal Home > Advanced Search > Author Details. Log in or Register to get access to full text downloads. ... Vol 12 (2008) - Articles On the wave equations of shallow water with rough bottom topography. Abstract · Vol 14 (2009) - Articles Energy generation in a plant due to variable sunlight intensity

  6. Author Details

    African Journals Online (AJOL)

    Author Details. Journal Home > Advanced Search > Author Details. Log in or Register to get access to full text downloads. ... Vol 45 (2016) - Articles From vectors to waves and streams: An alternative approach to semantic maps1. Abstract PDF · Vol 48 (2017) - Articles Introduction: 'n Klein ietsie for Johan Oosthuizen

  7. Author Details

    African Journals Online (AJOL)

    Author Details. Journal Home > Advanced Search > Author Details. Log in or Register to get access to full text downloads. ... to blast loadings. Abstract PDF · Vol 9, No 3S (2017): Special Issue - Articles Experimental and numerical investigation on blast wave propagation in soil structure. Abstract PDF. ISSN: 1112-9867.

  8. The seeds and the worms: Ludwik Fleck and the early history of germ theories

    DEFF Research Database (Denmark)

    Brorson, Stig

    2006-01-01

    -scientific "proto-ideas." In 1935, Fleck proposed that the history of germ theories could be approached through his thesis on proto-ideas. His proposal, however, remained little more than a vague suggestion and was never developed in further detail. This paper introduces the concept of proto-ideas and discusses...... the central epistemological and historiographical implications of Fleck's thesis. The Fleckian approach offers an attractive alternative to positivist reconstructions of the early history of germ theories and provides a useful framework for a deeper understanding of the sociocultural background......The Polish microbiologist and philosopher of science, Ludwik Fleck (1896-1961), was a pioneer in constructivist history and philosophy of science. Based on studies in the history of syphilis, Fleck hypothesized that many established scientific facts are linked, in their development, to pre...

  9. Author Details

    African Journals Online (AJOL)

    Author Details. Journal Home > Advanced Search > Author Details. Log in or Register to get access to full text downloads. ... Iliopsoas haematoma in a rugby player. Abstract PDF · Vol 29, No 1 (2017) - Articles The use of negative pressure wave treatment in athlete recovery. Abstract PDF. ISSN: 2078-516X. AJOL African ...

  10. Author Details

    African Journals Online (AJOL)

    Author Details. Journal Home > Advanced Search > Author Details. Log in or Register to get access to full text downloads. ... No 3S (2017): Special Issue - Articles Experimental and numerical investigation on blast wave propagation in soil structure. Abstract PDF · Vol 9, No 3S (2017): Special Issue - Articles Simulation on ...

  11. Author Details

    African Journals Online (AJOL)

    Author Details. Journal Home > Advanced Search > Author Details. Log in or Register to get access to full text downloads. ... Duwa, S S. Vol 8 (2004) - Articles Lower hybrid waves instability in a velocity–sheared inhomogenous charged dust beam. Abstract · Vol 9 (2005) - Articles The slide away theory of lower hybrid bursts

  12. Author Details

    African Journals Online (AJOL)

    Author Details. Journal Home > Advanced Search > Author Details. Log in or Register to get access to full text downloads. ... The use of negative pressure wave treatment in athlete recovery. Abstract PDF · Vol 29, No 1 (2017) - Articles The prevalence, risk factors predicting injury and the severity of injuries sustained during ...

  13. Author Details

    African Journals Online (AJOL)

    Author Details. Journal Home > Advanced Search > Author Details. Log in or Register to get access to full text downloads. ... Vol 29, No 1 (2017) - Articles The use of negative pressure wave treatment in athlete recovery. Abstract PDF · Vol 29, No 1 (2017) - Articles The prevalence, risk factors predicting injury and the ...

  14. Results of Detailed Hydrologic Characterization Tests - Fiscal Year 2000

    International Nuclear Information System (INIS)

    Spane, Frank A; Thorne, Paul D; Newcomer, Darrell R

    2001-01-01

    This report provides the results of detailed hydrologic characterization tests conducted within eleven Hanford Site wells during fiscal year 2000. Detailed characterization tests performed included groundwater-flow characterization; barometric response evaluation; slug tests; single-well tracer tests; constant-rate pumping tests; and in-well, vertical flow tests. Hydraulic property estimates obtained from the detailed hydrologic tests include transmissivity; hydraulic conductivity; specific yield; effective porosity; in-well, lateral flow velocity; aquifer-flow velocity; vertical distribution of hydraulic conductivity (within the well-screen section); and in-well, vertical flow velocity. In addition, local groundwater-flow characteristics (i.e., hydraulic gradient and flow direction) were determined for four sites where detailed well testing was performed

  15. Microbiologists’ Public Engagement Views and Behaviors †

    Science.gov (United States)

    Besley, John; Kahlor, Lee Ann; Koh, Hyeseung; Copple, Jacob; Yuan, Shupei

    2018-01-01

    In this study, we present results from an extensive survey of US-based microbiologists (adults) to explore these scientists’ perceptions and behaviors related to communicating their research. Specifically, we explored the frequency with which microbiologists engage in public communication, how they evaluate their public communication experiences, and the factors associated with their willingness to engage in face-to-face and online public communication in the future. Data from a multi-wave online survey suggest that microbiologists (N = 903) are somewhat frequent communicators who derive great value from their outreach efforts. The results further suggest that social and psychological drivers of future intentions to engage with the public are consistent with the Theory of Planned Behavior (TPB). Specifically, microbiologists with more positive attitudes toward engagement were more willing to partake in direct and online communication activities. Similarly, microbiologists who believe they possess communication skills are more willing than their less efficacious colleagues to do either type of outreach. Our results also indicate that more-senior and more-active researchers are more willing to participate in direct and online engagement. Implications for communication training are discussed. PMID:29904524

  16. Author Details

    African Journals Online (AJOL)

    Author Details. Journal Home > Advanced Search > Author Details. Log in or Register to get access to full text downloads. ... Isa, M.F.M.. Vol 9, No 3S (2017): Special Issue - Articles Experimental and numerical investigation on blast wave propagation in soil structure. Abstract PDF · Vol 9, No 3S (2017): Special Issue - ...

  17. Author Details

    African Journals Online (AJOL)

    Author Details. Journal Home > Advanced Search > Author Details. Log in or Register to get access to full text downloads. ... Abstract PDF · Vol 3, No 6 (2011) - Articles Mixed convection flow and heat transfer in a vertical wavy channel containing porous and fluid layer with traveling thermal waves. Abstract PDF · Vol 3, No 8 ...

  18. Author Details

    African Journals Online (AJOL)

    Author Details. Journal Home > Advanced Search > Author Details. Log in or Register to get access to full text downloads. ... Ismail, A. Vol 9, No 3S (2017): Special Issue - Articles Investigate of wave absorption performance for oil palm frond and empty fruit bunch at 5.8 GHz. Abstract PDF · Vol 9, No 3S (2017): Special Issue ...

  19. Molecular details of secretory phospholipase A2 from flax (Linum usitatissimum L.) provide insight into its structure and function.

    Science.gov (United States)

    Gupta, Payal; Dash, Prasanta K

    2017-09-11

    Secretory phospholipase A 2 (sPLA 2 ) are low molecular weight proteins (12-18 kDa) involved in a suite of plant cellular processes imparting growth and development. With myriad roles in physiological and biochemical processes in plants, detailed analysis of sPLA 2 in flax/linseed is meagre. The present work, first in flax, embodies cloning, expression, purification and molecular characterisation of two distinct sPLA 2 s (I and II) from flax. PLA 2 activity of the cloned sPLA 2 s were biochemically assayed authenticating them as bona fide phospholipase A 2 . Physiochemical properties of both the sPLA 2 s revealed they are thermostable proteins requiring di-valent cations for optimum activity.While, structural analysis of both the proteins revealed deviations in the amino acid sequence at C- & N-terminal regions; hydropathic study revealed LusPLA 2 I as a hydrophobic protein and LusPLA 2 II as a hydrophilic protein. Structural analysis of flax sPLA 2 s revealed that secondary structure of both the proteins are dominated by α-helix followed by random coils. Modular superimposition of LusPLA 2 isoforms with rice sPLA 2 confirmed monomeric structural preservation among plant phospholipase A 2 and provided insight into structure of folded flax sPLA 2 s.

  20. Providing detailed information about latent tuberculosis and compliance with the PPD test among healthcare workers in Israel: a randomized controlled study.

    Science.gov (United States)

    Taubman, Danielle; Titler, Nava; Edelstein, Hana; Elias, Mazen; Saliba, Walid

    2013-12-01

    The compliance of screening for latent tuberculosis (TB) with the tuberculin purified protein derivative (PPD) test is very low among healthcare workers (HCWs) in Israel. This randomized controlled study uses the Health Belief Model (HBM) as a conceptual framework to examine whether providing more information about latent TB and the PPD test increases the response rate for PPD screening among HCWs. All candidate HCWs for latent TB screening were randomly allocated to one of the following two invitations to perform the PPD test: regular letter (control group, n=97), and a letter with information about latent TB and the PPD test (intervention group, n=196). 293 HCWs were included (185 nurses, and 108 physicians). Overall, 36 (12.3%) HCWs were compliant with the PPD test screening. Compliance with PPD testing in the intervention group was not statistically different from the control group, RR 0.87 (95% CI, 0.46-1.65). Compliance for latent TB screening is low among HCWs in northeastern Israel. Providing detailed information about latent TB was not associated with increased test compliance. Understanding existing disparities in screening rates and potential barriers to latent TB screening among HCWs is important in order to move forward and successfully increase screening rates. Copyright © 2013 Ministry of Health, Saudi Arabia. Published by Elsevier Ltd. All rights reserved.

  1. Research on the Hotel Image Based on the Detail Service

    Science.gov (United States)

    Li, Ban; Shenghua, Zheng; He, Yi

    Detail service management, initially developed as marketing programs to enhance customer loyalty, has now become an important part of customer relation strategy. This paper analyzes the critical factors of detail service and its influence on the hotel image. We establish the theoretical model of influencing factors on hotel image and propose corresponding hypotheses. We use applying statistical method to test and verify the above-mentioned hypotheses. This paper provides a foundation for further study of detail service design and planning issues.

  2. [Nationwide survey among institutes of microbiology in academic medicine : Is the interdisciplinary approach the right way to treat patients with urogenital infections?

    Science.gov (United States)

    Schneidewind, L; Kranz, J; Schlager, D; Pelzer, A E

    2017-06-01

    Increasing antibiotic resistance is a current and severe problem in medicine, especially in urology. Multidisciplinary antibiotic stewardship programmes are an important approach to counteract increasing resistance rates. This approach includes collaboration between urologists and microbiologists. The primary endpoint was to describe the current setting of interdisciplinary work of urologists and microbiologists in university hospitals in Germany. The secondary endpoints were the identification of problems of this interdisciplinary approach in daily routine and implications for the future in patient treatment. A newly developed, 24-item questionnaire was sent to 34 German microbiology departments at medical universities between June and October 2016; the departments were contacted up to four times. Only complete questionnaires were included in our analysis. The response rate was 50.0%. In the majority of the urological cases a microbiologist was only contacted sporadically and asked for advice, but on the other hand most of the microbiologists think that this contact and discussion about the patient is reasonable and preferable. Of the respondents, 82.4% think that with a consequent interdisciplinary approach there might be lower antibiotic resistance rates in the future. One essential problem of ideal microbial diagnostics and therapeutic advice is that the microbiologist does not receive all relevant information upon request. This might be the case in up to 76.5%. Other problems are of economic nature or shortage of manpower. Interdisciplinary patient care between urologists and microbiologists is reasonable and preferable. This approach has the potential of decreasing antibiotic resistance rates in the future.

  3. IPUMS: Detailed global data on population characteristics

    Science.gov (United States)

    Kugler, T.

    2017-12-01

    Many new and exciting sources of data on human population distributions based on remote sensing, mobile technology, and other mechanisms are becoming available. These new data sources often provide fine scale spatial and/or temporal resolution. However, they typically focus on the location of population, with little or no information on population characteristics. The large and growing collection of data available through the IPUMS family of products complements datasets that provide spatial and temporal detail but little attribute detail by providing the full depth of characteristics covered by population censuses, including demographic, household structure, economic, employment, education, and housing characteristics. IPUMS International provides census microdata for 85 countries. Microdata provide the responses to every census question for each individual in a sample of households. Microdata identify the sub-national geographic unit in which a household is located, but for confidentiality reasons, identified units must include a minimum population, typically 20,000 people. Small-area aggregate data often describe much smaller geographic units, enabling study of detailed spatial patterns of population characteristics. However the structure of aggregate data tables is highly heterogeneous across countries, census years, and even topics within a given census, making these data difficult to work with in any systematic way. A recently funded project will assemble small-area aggregate population and agricultural census data published by national statistical offices. Through preliminary work collecting and cataloging over 10,000 tables, we have identified a small number of structural families that can be used to organize the many different structures. These structural families will form the basis for software tools to document and standardize the tables for ingest into a common database. Both the microdata and aggregate data are made available through IPUMS Terra

  4. Detailed design report for an operational phase panel-closure system

    International Nuclear Information System (INIS)

    1996-01-01

    Under contract to Westinghouse Electric Corporation (Westinghouse), Waste Isolation Division (WID), IT Corporation has prepared a detailed design of a panel-closure system for the Waste Isolation Pilot Plant (WIPP). Preparation of this detailed design of an operational-phase closure system is required to support a Resource Conservation and Recovery Act (RCRA) Part B permit application and a non-migration variance petition. This report describes the detailed design for a panel-closure system specific to the WIPP site. The recommended panel-closure system will adequately isolate the waste-emplacement panels for at least 35 years. This report provides detailed design and material engineering specifications for the construction, emplacement, and interface-grouting associated with a panel-closure system at the WIPP repository, which would ensure that an effective panel-closure system is in place for at least 35 years. The panel-closure system provides assurance that the limit for the migration of volatile organic compounds (VOC) will be met at the point of compliance, the WIPP site boundary. This assurance is obtained through the inherent flexibility of the panel-closure system

  5. Coordination and resource-related difficulties encountered by Quebec's public health specialists and infectious diseases/medical microbiologists in the management of A (H1N1 - a mixed-method, exploratory survey

    Directory of Open Access Journals (Sweden)

    Nhan Charles

    2012-02-01

    Full Text Available Abstract Background In Quebec, the influenza A (H1N1 pandemic was managed using a top-down style that left many involved players with critical views and frustrations. We aimed to describe physicians' perceptions - infectious diseases specialists/medical microbiologists (IDMM and public health/preventive medicine specialists (PHPMS - in regards to issues encountered with the pandemics management at the physician level and highlight suggested improvements for future healthcare emergencies. Methods In April 2010, Quebec IDMM and PHPMS physicians were invited to anonymously complete a web-based learning needs assessment. The survey included both open-ended and multiple-choice questions. Descriptive statistics were used to report on the frequency distribution of multiple choice responses whereas thematic content analysis was used to analyse qualitative data generated from the survey and help understand respondents' experience and perceptions with the pandemics. Results Of the 102 respondents, 85.3% reported difficulties or frustrations in their practice during the pandemic. The thematic analysis revealed two core themes describing the problems experienced in the pandemic management: coordination and resource-related difficulties. Coordination issues included communication, clinical practice guidelines, decision-making, roles and responsibilities, epidemiological investigation, and public health expert advisory committees. Resources issues included laboratory resources, patient management, and vaccination process. Conclusion Together, the quantitative and qualitative data suggest a need for improved coordination, a better definition of roles and responsibilities, increased use of information technologies, merged communications, and transparency in the decisional process. Increased flexibility and less contradiction in clinical practice guidelines from different sources and increased laboratory/clinical capacity were felt critical to the proper

  6. Results of Detailed Hydrologic Characterization Tests—Fiscal and Calendar Year 2005

    Energy Technology Data Exchange (ETDEWEB)

    Spane, Frank A.; Newcomer, Darrell R.

    2008-02-27

    This report provides the results of detailed hydrologic characterization tests conducted within selected Hanford Site wells during fiscal and calendar year 2005. Detailed characterization tests performed included groundwater-flow characterization, barometric response evaluation, slug tests, in-well vertical groundwater-flow assessments, and a single-well tracer and constant-rate pumping test. Hydraulic property estimates obtained from the detailed hydrologic tests include hydraulic conductivity, transmissivity, specific yield, effective porosity, in-well lateral and vertical groundwater-flow velocity, aquifer groundwater-flow velocity, and depth-distribution profiles of hydraulic conductivity. In addition, local groundwater-flow characteristics (i.e., hydraulic gradient and flow direction) were determined for a site where detailed well testing was performed. Results obtained from these tests provide hydrologic information that supports the needs of Resource Conservation and Recovery Act waste management area characterization as well as sitewide groundwater monitoring and modeling programs. These results also reduce the uncertainty of groundwater-flow conditions at selected locations on the Hanford Site.

  7. Medicare Referring Provider DMEPOS PUF

    Data.gov (United States)

    U.S. Department of Health & Human Services — This dataset, which is part of CMSs Medicare Provider Utilization and Payment Data, details information on Durable Medical Equipment, Prosthetics, Orthotics and...

  8. Family physicians' perceptions of academic detailing: a quantitative and qualitative study

    Directory of Open Access Journals (Sweden)

    O'Connor Nicolette

    2007-10-01

    Full Text Available Abstract Background The efficacy of academic detailing in changing physicians' knowledge and practice has been the subject of many primary research publications and systematic reviews. However, there is little written about the features of academic detailing that physicians find valuable or that affect their use of it. The goal of our project was to explore family physicians' (FPs perceptions of academic detailing and the factors that affect their use of it. Methods We used 2 methods to collect data, a questionnaire and semi-structured telephone interviews. We mailed questionnaires to all FPs in the Dalhousie Office of Continuing Medical Education database and analyzed responses of non-users and users of academic detailing. After a preliminary analysis of questionnaire data, we conducted semi-structured interviews with 7 FPs who did not use academic detailing and 17 who did use it. Results Overall response rate to the questionnaire was 33% (289/869. Response rate of non-users of academic detailing was 15% (60/393, of users was 48% (229/476. The 3 factors that most encouraged use of academic detailing were the topics selected, the evidence-based approach adopted, and the handout material. The 3 factors that most discouraged the use of academic detailing were spending office time doing CME, scheduling time to see the academic detailer, and having CME provided by a non-physician. Users of academic detailing rated it as being more valuable than other forms of CME. Generally, interview data confirmed questionnaire data with the exception that interview informants did not view having CME provided by a non-physician as a barrier. Interview informants mentioned that the evidence-based approach adopted by academic detailing had led them to more critically evaluate information from other CME programs, pharmaceutical representatives, and journal articles, but not advice from specialists. Conclusion Users of academic detailing highly value its educational

  9. 29 CFR 403.3 - Form of annual financial report-detailed report.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 2 2010-07-01 2010-07-01 false Form of annual financial report-detailed report. 403.3... LABOR LABOR-MANAGEMENT STANDARDS LABOR ORGANIZATION ANNUAL FINANCIAL REPORTS § 403.3 Form of annual financial report—detailed report. Every labor organization shall, except as expressly provided otherwise in...

  10. A detailed BWR recirculation loop model for RELAP

    Energy Technology Data Exchange (ETDEWEB)

    Araiza-Martínez, Enrique, E-mail: enrique.araiza@inin.gob.mx; Ortiz-Villafuerte, Javier, E-mail: javier.ortiz@inin.gob.mx; Castillo-Durán, Rogelio, E-mail: rogelio.castillo@inin.gob.mx

    2017-01-15

    Highlights: • A new detailed BWR recirculation loop model was developed for RELAP. • All jet pumps, risers, manifold, suction and control valves, and recirculation pump are modeled. • Model is tested against data from partial blockage of two jet pumps. • For practical applications, simulation results showed good agreement with available data. - Abstract: A new detailed geometric model of the whole recirculation loop of a BWR has been developed for the code RELAP. This detailed model includes the 10 jet pumps, 5 risers, manifold, suction and control valves, and the recirculation pump, per recirculation loop. The model is tested against data from an event of partial blockage at the entrance nozzle of one jet pump in both recirculation loops. For practical applications, simulation results showed good agreement with data. Then, values of parameters considered as figure of merit (reactor power, dome pressure, core flow, among others) for this event are compared against those from the common 1 jet pump per loop model. The results show that new detailed model led to a closer prediction of the reported power change. The detailed recirculation loop model can provide more reliable boundary condition data to a CFD models for studies of, for example, flow induced vibration, wear, and crack initiation.

  11. Air barrier details: How effective are they

    Energy Technology Data Exchange (ETDEWEB)

    A project was initiated to measure the air leakage through three typical details in wood frame walls: the header joist, electric outlets, and window openings. Three construction methods were tested: the poly approach, where a sealed internal polyethylene sheet and caulking provide the air barrier; an external air barrier approach using a continuous vapor permeable membrane sandwiched between two layers of external wall sheathing; and the airtight drywall approach (ADA), where the interior gypsum board finish along with framing and gaskets are the air barrier. Twelve sample panels using each of the three details were built using each of the construction approaches. A traditional wood-frame wall construction detail, with no effort made to create a continuous air barrier, was also built and tested for comparison. The samples were put in a test chamber so that air pressures could create infiltration or exfiltration through the panel under loads similar to those due to wind action. Measurements were made at several stages during construction of each sample to see the effect of different components on the air leakage. Overall, all but the traditional samples and the ADA electrical outlet panel exceeded the current tightness standards for glass and aluminum curtain walls. All three approaches could meet the airtightness standards of the R-2000 program. The total air leakage calculated for each approach is under 20% of that in traditional construction. Of the details tested, window detailing offers the greatest potential for increasing overall airtightness compared to traditional methods. 1 ref., 2 figs., 1 tab.

  12. Microbiologists Just Want to Have Fun

    Directory of Open Access Journals (Sweden)

    Heather M. Seitz

    2012-09-01

    Full Text Available Review of: Non-technical online microbial resources that entertain, engage, and promote microbiology thorugh music, comics, and gaming. Resources include Food Safety Music, Pandemic 2, Microbe Kombat, and The Great Flu.

  13. On Detailing in Contemporary Architecture

    DEFF Research Database (Denmark)

    Kristensen, Claus; Kirkegaard, Poul Henning

    2010-01-01

    Details in architecture have a significant influence on how architecture is experienced. One can touch the materials and analyse the detailing - thus details give valuable information about the architectural scheme as a whole. The absence of perceptual stimulation like details and materiality...... / tactility can blur the meaning of the architecture and turn it into an empty statement. The present paper will outline detailing in contemporary architecture and discuss the issue with respect to architectural quality. Architectural cases considered as sublime piece of architecture will be presented...

  14. Infections and their control: a historical perspective Swb Newsom Infections and their control: a historical perspective Sage/Infection Prevention Society £17.95 235pp 9781849204538 1849204535 [Formula: see text].

    Science.gov (United States)

    2010-10-27

    BILL NEWSOM, an eminent, but now retired, medical microbiologist, provides a personal but engaging review of infections and our attempts to control them. it is a fascinating social history of what has become an essential service, and Newsom highlights the need to be aware of past struggles and avoid repeating mistakes.

  15. Author Details

    African Journals Online (AJOL)

    Journal Home > Advanced Search > Author Details. Log in or Register ... (2013) - Articles Technical Note: Development of a Photobioreactor for Microalgae Culture ... Design, Construction and Evaluation of Motorized Okra Slicer Abstract PDF ...

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    Journal Home > Advanced Search > Author Details. Log in or Register to ... No 1 (2014) - Articles Knowledge and Attitudes towards Basic Cardiopulmonary Resuscitation (CPR) among Community Nurses in Remo Area of Ogun State, Nigeria

  17. Author Details

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    Journal Home > Advanced Search > Author Details ... Design and Implementation of an M/M/1 Queuing Model Algorithm and its Applicability in ... Vehicle Identification Technology to Intercept Small Arms and Ammunition on Nigeria Roads

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    Journal Home > Advanced Search > Author Details. Log in or ... The prevention of mother-to-child HIV transmission programme and infant feeding practices ... Evaluation of a diagnostic algorithm for smear-negative pulmonary tuberculosis in ...

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    Journal Home > Advanced Search > Author Details. Log in or Register to get ... Optical bus of centralized relay protection and automation system of medium voltage switchgear for data collection and transmission. Abstract PDF. ISSN: 1112- ...

  20. Medicare Referring Provider DMEPOS PUF CY2013

    Data.gov (United States)

    U.S. Department of Health & Human Services — This dataset, which is part of CMSs Medicare Provider Utilization and Payment Data, details information on Durable Medical Equipment, Prosthetics, Orthotics and...

  1. Revisiting the Seductive Details Effect in Multimedia Learning: Context-Dependency of Seductive Details

    Science.gov (United States)

    Ozdemir, Devrim; Doolittle, Peter

    2015-01-01

    The purpose of this study was to investigate the effects of context-dependency of seductive details on recall and transfer in multimedia learning environments. Seductive details were interesting yet irrelevant sentences in the instructional text. Two experiments were conducted. The purpose of Experiment 1 was to identify context-dependent and…

  2. Clinical microbiology during the Vietnam War.

    Science.gov (United States)

    Washington, Michael; Brown, Matthew; Palys, Thomas; Tyner, Stuart; Bowden, Robert

    2009-11-01

    During the period of 1965-1968, over two dozen Army microbiologists were deployed to various locations in Southeast Asia in support of the Vietnam War. Their role was to serve both a clinical laboratory mission/function at the mobile Army surgical hospital and mobile laboratory level as well as to perform research roles in all of the facilities. They were essential to the formulation of medical intelligence as well as to the practice of operational medicine in the deployed environment. The results of their laboratory investigations provided commanders and military physicians with critical medical information for patient care, outbreak investigation, and forensic analysis. As with many soldiers in support of the infantry and armor combat forces, most of the work occurs behind the scenes and their contributions are often left out of the historical literature. This article presents a brief overview of microbiology performed by Army microbiologists during the Vietnam War.

  3. Author Details

    African Journals Online (AJOL)

    Radwan M.D, Mona Ahmed. Vol 12, No 1 (2000) - Articles RELAPSING REMITTING MULTIPLE SCLEROSIS: CT AND MRI IMAGING VS CLINICAL FINDINGIN THE DIAGNOSIS AND DETERMINATION OF DISEASE ACTIVITY. Details. ISSN: 1110-5607. AJOL African Journals Online. HOW TO USE AJOL... for Researchers ...

  4. Recent developments in the detailed modelling of power house environmental conditions using GOTHIC

    International Nuclear Information System (INIS)

    Wong, R.C.; Fluke, R.J.; Yim, K.; Rossitter, B.G.

    1997-01-01

    Environmental qualification of safety equipment in the powerhouse requires detailed information on the predicted harsh conditions that can arise following a steam line break. Although lumped parameter codes provide quick assessments of global conditions, the results are unsatisfactory because the spatial detail needed to evaluate specific equipment, or indeed to optimize and confirm the design adequacy of mitigating features, is not available. To overcome these problems, new models have been developed to provide detailed three-dimensional information using the GOTHIC code. Furthermore, new animated graphical displays help the designer visualize and fully comprehend the buoyancy driven steam flow within the powerhouse. This has lead to quick optimization of the placement, size and opening time of the emergency venting system, thereby mitigating the conditions for which safety equipment must be qualified. This has resulted in significant cost savings for the environmental qualification programme. (author)

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    African Journals Online (AJOL)

    Green, J.M.. Vol 10, No 1 (2001) - Articles Information from Radio Telemetry on movements and exploitation of naturalized Rainbow trout, Oncorhynchus mykiss (Walbaum), in Kenya cold water streams. Details. ISSN: 0002-0036. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians ...

  6. Adapting Bioretention Construction Details to Local Practices in Finland

    Directory of Open Access Journals (Sweden)

    Outi Tahvonen

    2018-01-01

    Full Text Available Bioretention is a method of storm water management that includes several processes following the natural hydrological cycle. Bioretention, or variations of it, include rain gardens and bioswales, infiltrates, filtrates, evapotranspirates, and help to store and manage storm water run-off. A bioretention cell retains water, removes pollutants, and provides water elements for urban green areas. Although bioretention is a promising method for multifunctional storm water management, its construction details should not be copied from other climatic areas. A direct application may dismiss local conditions, materials, and construction practices. This study aimed to adapt construction details for bioretention to Finnish local practices and conditions and to formulate bioretention constructions that balance water, soil, and vegetation. First, construction details were reviewed, then local adaptations were applied, and finally, the application and two variations of growing media in two construction depths were tested in a test field in Southern Finland. Sandy growing media allowed the efficient retention of water during the first year, but failed to provide vital growth. The use of topsoil and compost in the growing media improved growth, but held high electrical conductivity after infiltration. All the experimental cells in the test field showed activity during the melting periods, both during winter and spring. If bioretention plays a multifunctional role in urban design and engineered ecology, the design parameters should not only focus on storm water quantity, but also on quality management and vegetation growth.

  7. Author Details

    African Journals Online (AJOL)

    Aderinokun, GA. Vol 9, No 1 (1999) - Articles Relative Influence Of Sociodemographic Variables On Oral Health And Habits Of Some Nigerian School Children Abstract · Vol 9, No 4 (1999) - Articles Oral health services in Nigeria Details. ISSN: 0189-2657. AJOL African Journals Online. HOW TO USE AJOL.

  8. Author Details

    African Journals Online (AJOL)

    Development of a trap to contaminate variegated grasshoppers (Zonocerus variegatus L.) (Orthoptera: Pyrgomorphidae) with Metarrhyzium flavo-viride Gams & Rozsypal in the field. Details · Vol 40, No 1 (2007) - Articles Yam pests in the Ashanti and Brong Ahafo regions of Ghana: A study of farmers\\' indigenous technical ...

  9. Author Details

    African Journals Online (AJOL)

    Geotechnical properties of lateritic soil developed over quartz schist in Ishara area, south western Nigeria Details · Vol 44, No 1 (2008) - Articles Comparative study of the influence of cement and lime stabilization on geotechnical properties of lateritic soil derived from pegmatite in Ago-Iwoye area, southwestern Nigeria

  10. Author Details

    African Journals Online (AJOL)

    SAMA, G. Vol 2 (2002): Supplement - Articles A Longitudinal Study of the Role of T Cell subset, Th1/Th2 cytokines and antiplasmodial antibodies in uncomplicated Malaria in a Village Population Chronically Exposed to Plasmodium falciparum Malaria. Details PDF · AJOL African Journals Online. HOW TO USE AJOL.

  11. Author Details

    African Journals Online (AJOL)

    KOUONTCHOU, Samuel. Vol 2 (2002): Supplement - Articles Prevalence of Multiple Concomitant Intestinal Parasitic Infections in Simbok a Malaria Endemic Village in Cameroon. Details PDF · Vol 2 (2002): Supplement - Articles A Longitudinal Study of the Role of T Cell subset, Th1/Th2 cytokines and antiplasmodial ...

  12. Author Details

    African Journals Online (AJOL)

    ALAKE, J. Vol 2 (2002): Supplement - Articles A Longitudinal Study of the Role of T Cell subset, Th1/Th2 cytokines and antiplasmodial antibodies in uncomplicated Malaria in a Village Population Chronically Exposed to Plasmodium falciparum Malaria. Details PDF · AJOL African Journals Online. HOW TO USE AJOL.

  13. Author Details

    African Journals Online (AJOL)

    A Preliminary Investigation of Relative Frequency of Undiagnosed and Previously Diagnosed Hypertension Before First Stroke in a Lagos Hospital Abstract · Vol 9, No 4 (1999) - Articles Localised tetanus in Lagos, Nigeria Details · Vol 9, No 4 (1999) - Articles Stroke with localised infarction of Wernicke's Area misdiagnosed ...

  14. Author Details

    African Journals Online (AJOL)

    Journal Home > Advanced Search > Author Details. Log in or Register to get access to full text ... Abstract · Vol 17 (2010) - Articles Investigating The Travelling Wave Solution For an SIR Endemic Disease Model With No Disease Related Death (When The Spatial Spread Of The Susceptible Is Not Negligible). Abstract.

  15. Author Details

    African Journals Online (AJOL)

    Rakotonirina, Alice. Vol 2, No 2 (2002) - Articles Effect of the decoction of rhizomes of Cyperus articulatus on bicuculline-, N-methyl-D-aspartate- and strychnine-induced behavioural excitation and convulsions in mice. Details PDF · AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians ...

  16. Pharmaceutical crystallography: is there a devil in the details?

    DEFF Research Database (Denmark)

    Bond, A. D.

    2012-01-01

    Modern instruments for small-molecule crystallography continue to become more sophisticated and more automated. This technical progress provides a basis for frontier research in chemical and pharmaceutical crystallography, but it also encourages analytical crystallographers to become more...... are presented for pharmaceutical compounds, and the potential importance of the "details" in pharmaceutical crystallography is discussed....

  17. Author Details

    African Journals Online (AJOL)

    NENTY, N. JOHNSON. Vol 7, No 3 (2001) - Articles Common errors and perfomance of students in junior secondary mathematics certificate examinations in Cross River State, Nigeria Details PDF. ISSN: 1118-0579. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's ...

  18. Author Details

    African Journals Online (AJOL)

    QUAKYI, A.I.. Vol 2 (2002): Supplement - Articles A Longitudinal Study of the Role of T Cell subset, Th1/Th2 cytokines and antiplasmodial antibodies in uncomplicated Malaria in a Village Population Chronically Exposed to Plasmodium falciparum Malaria. Details PDF · AJOL African Journals Online. HOW TO USE AJOL.

  19. Author Details

    African Journals Online (AJOL)

    Admasu, Assefa. Vol 22, No 2 (1999) - Articles Preliminary evaluation of Phytomyza orobanchia (Diptera: Agromyzidae) as a controller of Orobanche spp in Ethiopia Details PDF. ISSN: 2520–7997. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL ...

  20. Author Details

    African Journals Online (AJOL)

    Journal Home > Advanced Search > Author Details. Log in or Register to get access to full text downloads. ... Obtaining the green's function for electromagnetic waves propagating in layered in-homogeneous thin film media of spherical particles on a substrate. Abstract · Vol 20, No 2 (2008) - Articles solution growth and ...

  1. Author Details

    African Journals Online (AJOL)

    Lema, VM. Vol 80, No 9 (2003): - Articles Fournier's gangrene complicating vasectomy. Details PDF · Vol 86, No 6 (2009) - Articles Therapeutic misconception and clinical trials in sub-saharan Africa: A review. Abstract PDF · Vol 86, No 11 (2009) - Articles HIV/AIDS and pregnancy-related deaths in Blantyre, Malawi

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    African Journals Online (AJOL)

    Motabagani, MA. Vol 80, No 9 (2003): - Articles Anomalies of the renal, phrenic and suprarenal arteries: Case Report Details PDF · Vol 81, No 3 (2004): - Articles Morphological study of the uncommon rectus sterni muscle in German cadavers. Abstract PDF. ISSN: 0012-835X. AJOL African Journals Online. HOW TO USE ...

  3. Author Details

    African Journals Online (AJOL)

    Ibeabuchi, NM. Vol 10, No 3 (2000) - Articles Comparison of the effects of Methylsalicylate Cream with cryotherapy on delayed onset muscle soreness. Details · Vol 22, No 2 (2012) - Articles X-ray Pelvimetry And Labour Outcome In Term Pregnancy In A Rural Nigerian Population Abstract. ISSN: 0189-2657. AJOL African ...

  4. Raising the Bar for Microbiologists | IDRC - International ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2010-12-09

    Dec 9, 2010 ... We hope to create a new nurturing environment where research can flourish and ... out with diagnostics, determining the frequency and number of cases. ... Bridging the gap between farmers and supermarkets in Nicaragua.

  5. Mathematical modeling provides kinetic details of the human immune response to vaccination

    Directory of Open Access Journals (Sweden)

    Dustin eLe

    2015-01-01

    Full Text Available With major advances in experimental techniques to track antigen-specific immune responses many basic questions on the kinetics of virus-specific immunity in humans remain unanswered. To gain insights into kinetics of T and B cell responses in human volunteers we combine mathematical models and experimental data from recent studies employing vaccines against yellow fever and smallpox. Yellow fever virus-specific CD8 T cell population expanded slowly with the average doubling time of 2 days peaking 2.5 weeks post immunization. Interestingly, we found that the peak of the yellow fever-specific CD8 T cell response is determined by the rate of T cell proliferation and not by the precursor frequency of antigen-specific cells as has been suggested in several studies in mice. We also found that while the frequency of virus-specific T cells increases slowly, the slow increase can still accurately explain clearance of yellow fever virus in the blood. Our additional mathematical model describes well the kinetics of virus-specific antibody-secreting cell and antibody response to vaccinia virus in vaccinated individuals suggesting that most of antibodies in 3 months post immunization are derived from the population of circulating antibody-secreting cells. Taken together, our analysis provides novel insights into mechanisms by which live vaccines induce immunity to viral infections and highlight challenges of applying methods of mathematical modeling to the current, state-of-the-art yet limited immunological data.

  6. Mathematical modeling provides kinetic details of the human immune response to vaccination.

    Science.gov (United States)

    Le, Dustin; Miller, Joseph D; Ganusov, Vitaly V

    2014-01-01

    With major advances in experimental techniques to track antigen-specific immune responses many basic questions on the kinetics of virus-specific immunity in humans remain unanswered. To gain insights into kinetics of T and B cell responses in human volunteers we combined mathematical models and experimental data from recent studies employing vaccines against yellow fever and smallpox. Yellow fever virus-specific CD8 T cell population expanded slowly with the average doubling time of 2 days peaking 2.5 weeks post immunization. Interestingly, we found that the peak of the yellow fever-specific CD8 T cell response was determined by the rate of T cell proliferation and not by the precursor frequency of antigen-specific cells as has been suggested in several studies in mice. We also found that while the frequency of virus-specific T cells increased slowly, the slow increase could still accurately explain clearance of yellow fever virus in the blood. Our additional mathematical model described well the kinetics of virus-specific antibody-secreting cell and antibody response to vaccinia virus in vaccinated individuals suggesting that most of antibodies in 3 months post immunization were derived from the population of circulating antibody-secreting cells. Taken together, our analysis provided novel insights into mechanisms by which live vaccines induce immunity to viral infections and highlighted challenges of applying methods of mathematical modeling to the current, state-of-the-art yet limited immunological data.

  7. Author Details

    African Journals Online (AJOL)

    Brown, Duncan. Vol 16, No 2 (2002): Continental Africans & the Question of Identity - Articles Environment and Identity: Douglas Livingstone's A Littoral Zone Details. ISSN: 0256-004. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's ...

  8. Author Details

    African Journals Online (AJOL)

    SONUGA, F A. Vol 6, No 1 (2000) - Articles Geophysical investigation of Karkarku earthdam embankment. Details. ISSN: 1118-0579. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of Use · Contact AJOL ...

  9. Author Details

    African Journals Online (AJOL)

    Journal Home > Advanced Search > Author Details. Log in or Register to get access to full text downloads. ... Vol 8 (2004) - Articles Further on stokes expansions for the finite amplitude water waves. Abstract · Vol 11 (2007) - Articles On the effects of wave steepness on higher order Stokes waves. Abstract. ISSN: 1116-4336.

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    African Journals Online (AJOL)

    Focho, DA. Vol 2, No 1 (2002) - Articles Observations on the Meiotic Process in the African Pest Grasshopper Taphronota thaelephora Stal. (Orthoptera : Pyrgomorphidae) Details PDF · AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's ...

  11. Monte Carlo methods beyond detailed balance

    NARCIS (Netherlands)

    Schram, Raoul D.; Barkema, Gerard T.|info:eu-repo/dai/nl/101275080

    2015-01-01

    Monte Carlo algorithms are nearly always based on the concept of detailed balance and ergodicity. In this paper we focus on algorithms that do not satisfy detailed balance. We introduce a general method for designing non-detailed balance algorithms, starting from a conventional algorithm satisfying

  12. Author Details

    African Journals Online (AJOL)

    McCarthy, Greg. Vol 15, No 1 (2001): Media Freedom and Human Rights - Articles Caught between Empires: Ambivalence in Australian Films Details. ISSN: 0256-004. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and ...

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    African Journals Online (AJOL)

    Ligthelm, A.A.. Vol 5, No 2 (2001) - Articles Community attitudes towards Casinos and the estimated magnitude of problem gambling The Mpumalanga case. Details PDF. ISSN: 1027-4332. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's ...

  14. Author Details

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    Comarof, Jean. Vol 1999, No 3-4 (1999) - Articles Alien-Nation: Zombies, Immigrants and Millennial Capitalism Details. ISSN: 0850-8712. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of Use · Contact ...

  15. Author Details

    African Journals Online (AJOL)

    Njubi, Francis. Vol 15, No 1 (2001): Media Freedom and Human Rights - Articles New Media, Old Struggles: Pan Africanism, Anti-racism and Information Technology Details. ISSN: 0256-004. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's ...

  16. Author Details

    African Journals Online (AJOL)

    Journal Home > Advanced Search > Author Details. Log in or Register to get access to full text downloads. ... Okeke, EO. Vol 10 (2006) - Articles Analysis of Stokes waves theory as a diffusion problem. Abstract · Vol 11 (2007) - Articles On the impact of wave-current on Stokes waves. Abstract. ISSN: 1116-4336. AJOL African ...

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    African Journals Online (AJOL)

    Love, Alison. Vol 29, No 2 (2002) - Articles Policy-makers, the Press and Politics: Reporting a Public Policy Document Details. ISSN: 0379-0622. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of Use ...

  18. Author Details

    African Journals Online (AJOL)

    Idowu, OO. Vol 8, No 1 (2003) - Articles Evaluation of Different Substrates and Combinations on the Growth of Pleurotus pulmonarius (Fries) Quelet (Sajor-caju) Details. ISSN: 1118-2733. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's ...

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    African Journals Online (AJOL)

    Odigie, IP. Vol 10, No 4 (2000) - Articles High dose vitamin E administration attenuates hypertensin in 2-Kidney 1 Clip Goldblatt hypertensive rats. Details. ISSN: 0189-2657. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms ...

  20. Author Details

    African Journals Online (AJOL)

    Warnorff, DK. Vol 13, No 4 (2001) - Articles Development of a scoring system for the diagnosis of tuberculous lymphadenitis. Details PDF. ISSN: 1995-7262. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions ...

  1. A detailed phylogeny for the Methanomicrobiales

    Science.gov (United States)

    Rouviere, P.; Mandelco, L.; Winker, S.; Woese, C. R.

    1992-01-01

    The small subunit rRNA sequence of twenty archaea, members of the Methanomicrobiales, permits a detailed phylogenetic tree to be inferred for the group. The tree confirms earlier studies, based on far fewer sequences, in showing the group to be divided into two major clusters, temporarily designated the "methanosarcina" group and the "methanogenium" group. The tree also defines phylogenetic relationships within these two groups, which in some cases do not agree with the phylogenetic relationships implied by current taxonomic names--a problem most acute for the genus Methanogenium and its relatives. The present phylogenetic characterization provides the basis for a consistent taxonomic restructuring of this major methanogenic taxon.

  2. The Devil Is in the Details: Evidence from the GED on the Role of Examination System Details in Determining Who Passes. NCSALL Reports #16.

    Science.gov (United States)

    Tyler, John H.; Murnane, Richard J.; Willett, John B.

    A study used data from a long-standing examination system, the General Educational Development (GED) certificate, to illustrate that the details of examination systems have marked impacts on the number of test takers who obtain the desired credential and on the racial/ethnic composition of passers. Data provided by the Florida Department of…

  3. Author Details

    African Journals Online (AJOL)

    EKPA, O. D.. Vol 7, No 2 (2001) - Articles Variental differences AND polymorphism in palm oil: a case study of palm oils blended with coconut oil. Details PDF. ISSN: 1118-0579. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners ...

  4. Author Details

    African Journals Online (AJOL)

    Kioni, P N. Vol 9, No 1 (2007) - Articles Detailed structure of pipe flow with water hammer oscillations. Abstract. ISSN: 1561-7645. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of Use · Contact AJOL ...

  5. Author Details

    African Journals Online (AJOL)

    Legwaila, GM. Vol 12 (2003) - Articles Review of sweet sorghum: a potential cash and forage crop in Botswana Details. ISSN: 1021-0873. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of Use · Contact ...

  6. Author Details

    African Journals Online (AJOL)

    Akum, ZE. Vol 1, No 3 (2001) - Articles Basic home range characteristics for the conservation of the African grey parrot in the Korup national park, Cameroon Details PDF · AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms ...

  7. Author Details

    African Journals Online (AJOL)

    Bobcokono, Irene Yatabene. Vol 1, No 1 (2001) - Articles Utilisation du papier filtre dans la gestion de programme de lute contre le SIDA au Cameroun Details PDF · AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and ...

  8. Author Details

    African Journals Online (AJOL)

    Erasmus, GJ. Vol 1, No 1 (2001) - Articles Genetic parameter estimates for growth traits in purebred Gudali and two-breed synthetic Wakwa beef cattle in a tropical environment. Details PDF · AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's ...

  9. The Effects of Seductive Details in an Inflatable Planetarium

    Science.gov (United States)

    Gillette, Sean

    Astronomy is becoming a forgotten science, which is evident by its relatively low enrollment figures compared to biology, chemistry, and physics. A portable inflatable planetarium brings relevance back to astronomy and offers support to students and educators by simulating realistic astronomical environments. This study sought to determine if learning is improved in an inflatable planetarium by adhering to the design principles of the cognitive theory of multimedia learning (CTML), specifically the coherence principle, in an authentic classroom. Two groups of 5th grade students of similar ability were purposefully assigned using a 1-teacher-to-many-students format with mean lesson lengths of 34 minutes. The experimental group was differentiated with seductive details, defined as interesting but irrelevant facts that can distract learning. The control group ( n = 28), with seductive details excluded, outperformed the experimental group (n = 28), validating the coherence principle and producing a Cohen's effect size of medium practical significance (d = 0.4). These findings suggest that CTML, when applied to planetarium instruction, does increase student learning and that seductive details do have a negative effect on learning. An adult training project was created to instruct educators on the benefits of CTML in astronomy education. This study leads to positive social change by highlighting astronomy education while providing educators with design principles of CTML in authentic settings to maximize learning, aid in the creation of digital media (astronomical simulations/instructional lessons for planetariums) and provide valuable training for owners of inflatable planetariums with the eventual goal of increasing student enrollment of astronomy courses at the local level.

  10. Bionanomaterials for skin regeneration

    CERN Document Server

    Leonida, Mihaela D

    2016-01-01

    This book gives a concise overview of bionanomaterials with applications for skin regeneration. The advantages and challenges of nanoscale materials are covered in detail, giving a basic view of the skin structure and conditions that require transdermal or topical applications. Medical applications, such as wound healing, care for burns, skin disease, and cosmetic care, such as aging of the skin and photodamage, and how they benefit from bionanomaterials, are described in detail. A final chapter is devoted to the ethical and social issues related to the use of bionanomaterials for skin regeneration. This is an ideal book for researchers in materials science, medical scientists specialized in dermatology, and cosmetic chemists working in formulations. It can also serve as a reference for nanotechnologists, dermatologists, microbiologists, engineers, and polymer chemists, as well as students studying in these fields.

  11. Bacterial-Fungal Interactions: Hyphens between Agricultural, Clinical, Environmental, and Food Microbiologists

    Science.gov (United States)

    Frey-Klett, P.; Burlinson, P.; Deveau, A.; Barret, M.; Tarkka, M.; Sarniguet, A.

    2011-01-01

    Summary: Bacteria and fungi can form a range of physical associations that depend on various modes of molecular communication for their development and functioning. These bacterial-fungal interactions often result in changes to the pathogenicity or the nutritional influence of one or both partners toward plants or animals (including humans). They can also result in unique contributions to biogeochemical cycles and biotechnological processes. Thus, the interactions between bacteria and fungi are of central importance to numerous biological questions in agriculture, forestry, environmental science, food production, and medicine. Here we present a structured review of bacterial-fungal interactions, illustrated by examples sourced from many diverse scientific fields. We consider the general and specific properties of these interactions, providing a global perspective across this emerging multidisciplinary research area. We show that in many cases, parallels can be drawn between different scenarios in which bacterial-fungal interactions are important. Finally, we discuss how new avenues of investigation may enhance our ability to combat, manipulate, or exploit bacterial-fungal complexes for the economic and practical benefit of humanity as well as reshape our current understanding of bacterial and fungal ecology. PMID:22126995

  12. DNS with detailed and tabulated chemistry of engine relevant igniting systems

    NARCIS (Netherlands)

    Bekdemir, C.; Somers, L.M.T.; Goey, de L.P.H.

    2014-01-01

    Developments in modern engine technology are moving towards a regime with fuel injection uncoupled from combustion. Auto-ignition is an essential characteristic in these systems. The accurate prediction of this chemical process is of paramount importance. Tabulation techniques can provide a detailed

  13. Devil in the details? Developmental dyslexia and visual long-term memory for details.

    Science.gov (United States)

    Huestegge, Lynn; Rohrßen, Julia; van Ermingen-Marbach, Muna; Pape-Neumann, Julia; Heim, Stefan

    2014-01-01

    Cognitive theories on causes of developmental dyslexia can be divided into language-specific and general accounts. While the former assume that words are special in that associated processing problems are rooted in language-related cognition (e.g., phonology) deficits, the latter propose that dyslexia is rather rooted in a general impairment of cognitive (e.g., visual and/or auditory) processing streams. In the present study, we examined to what extent dyslexia (typically characterized by poor orthographic representations) may be associated with a general deficit in visual long-term memory (LTM) for details. We compared object- and detail-related visual LTM performance (and phonological skills) between dyslexic primary school children and IQ-, age-, and gender-matched controls. The results revealed that while the overall amount of LTM errors was comparable between groups, dyslexic children exhibited a greater portion of detail-related errors. The results suggest that not only phonological, but also general visual resolution deficits in LTM may play an important role in developmental dyslexia.

  14. Strengthening of competence planning truss through instructional media development details

    Science.gov (United States)

    Handayani, Sri; Nurcahyono, M. Hadi

    2017-03-01

    Competency-Based Learning is a model of learning in which the planning, implementation, and assessment refers to the mastery of competencies. Learning in lectures conducted in the framework for comprehensively realizing student competency. Competence means the orientation of the learning activities in the classroom must be given to the students to be more active learning, active search for information themselves and explore alone or with friends in learning activities in pairs or in groups, learn to use a variety of learning resources and printed materials, electronic media, as well as environment. Analysis of learning wooden structure known weakness in the understanding of the truss detail. Hence the need for the development of media that can provide a clear picture of what the structure of the wooden horses and connection details. Development of instructional media consisted of three phases of activity, namely planning, production and assessment. Learning Media planning should be tailored to the needs and conditions necessary to provide reinforcement to the mastery of competencies, through the table material needs. The production process of learning media is done by using hardware (hardware) and software (software) to support the creation of a medium of learning. Assessment of the media poduk yan include feasibility studies, namely by subject matter experts, media experts, while testing was done according to the student's perception of the product. The results of the analysis of the materials for the instructional aspects of the results obtained 100% (very good) and media analysis for the design aspects of the media expressed very good with a percentage of 88.93%. While the analysis of student perceptions expressed very good with a percentage of 84.84%. Media Learning Truss Details feasible and can be used in the implementation of learning wooden structure to provide capacity-building in planning truss

  15. Clinical professional governance for detailed clinical models.

    Science.gov (United States)

    Goossen, William; Goossen-Baremans, Anneke

    2013-01-01

    This chapter describes the need for Detailed Clinical Models for contemporary Electronic Health Systems, data exchange and data reuse. It starts with an explanation of the components related to Detailed Clinical Models with a brief summary of knowledge representation, including terminologies representing clinic relevant "things" in the real world, and information models that abstract these in order to let computers process data about these things. Next, Detailed Clinical Models are defined and their purpose is described. It builds on existing developments around the world and accumulates in current work to create a technical specification at the level of the International Standards Organization. The core components of properly expressed Detailed Clinical Models are illustrated, including clinical knowledge and context, data element specification, code bindings to terminologies and meta-information about authors, versioning among others. Detailed Clinical Models to date are heavily based on user requirements and specify the conceptual and logical levels of modelling. It is not precise enough for specific implementations, which requires an additional step. However, this allows Detailed Clinical Models to serve as specifications for many different kinds of implementations. Examples of Detailed Clinical Models are presented both in text and in Unified Modelling Language. Detailed Clinical Models can be positioned in health information architectures, where they serve at the most detailed granular level. The chapter ends with examples of projects that create and deploy Detailed Clinical Models. All have in common that they can often reuse materials from earlier projects, and that strict governance of these models is essential to use them safely in health care information and communication technology. Clinical validation is one point of such governance, and model testing another. The Plan Do Check Act cycle can be applied for governance of Detailed Clinical Models

  16. The Engaged Microbiologist: Bringing the Microbiological Sciences to the K-12 Community.

    Science.gov (United States)

    Westenberg, David J

    2016-03-01

    Exposing K-12 students to cutting edge science that impacts their daily lives can bring classroom lessons to life. Citizen-science projects are an excellent way to bring high-level science to the classroom and help satisfy one of the cornerstone concepts of the Next Generation Science Standards (NGSS), "engaging in practices that scientists and engineers actually use." This can be a daunting task for teachers who may lack the background or resources to integrate these projects into the classroom. This is where scientific societies such as the American Society for Microbiology (ASM) can play a critical role. ASM encourages its members to engage with the K-12 community by providing networking opportunities and resources for ASM members and K-12 teachers to work together to bring microbiology into the classroom. Journal of Microbiology & Biology Education.

  17. The Engaged Microbiologist: Bringing the Microbiological Sciences to the K–12 Community

    Directory of Open Access Journals (Sweden)

    David J. Westenberg

    2015-12-01

    Full Text Available Exposing K–12 students to cutting edge science that impacts their daily lives can bring classroom lessons to life. Citizen-science projects are an excellent way to bring high-level science to the classroom and help satisfy one of the cornerstone concepts of the Next Generation Science Standards (NGSS, “engaging in practices that scientists and engineers actually use.” This can be a daunting task for teachers who may lack the background or resources to integrate these projects into the classroom. This is where scientific societies such as the American Society for Microbiology (ASM can play a critical role. ASM encourages its members to engage with the K–12 community by providing networking opportunities and resources for ASM members and K–12 teachers to work together to bring microbiology into the classroom.

  18. Devil in the Details? Developmental Dyslexia and Visual Long-Term Memory for Details

    Directory of Open Access Journals (Sweden)

    Lynn eHuestegge

    2014-07-01

    Full Text Available Cognitive theories on causes of developmental dyslexia can be divided into language-specific and general accounts. While the former assume that words are special in that associated processing problems are rooted in language-related cognition (e.g., phonology deficits, the latter propose that dyslexia is rather rooted in a general impairment of cognitive (e.g., visual and/or auditory processing streams. In the present study, we examined to what extent dyslexia (typically characterized by poor orthographic representations may be associated with a general deficit in visual long-term memory for details. We compared object- and detail-related visual long-term memory performance (and phonological skills between dyslexic primary school children and IQ-, age- and gender-matched controls. The results revealed that while the overall amount of long-term memory errors was comparable between groups, dyslexic children exhibited a greater portion of detail-related errors. The results suggest that not only phonological, but also general visual resolution deficits in long-term memory may play an important role in developmental dyslexia.

  19. Template Assembly for Detailed Urban Reconstruction

    KAUST Repository

    Nan, Liangliang

    2015-05-04

    We propose a new framework to reconstruct building details by automatically assembling 3D templates on coarse textured building models. In a preprocessing step, we generate an initial coarse model to approximate a point cloud computed using Structure from Motion and Multi View Stereo, and we model a set of 3D templates of facade details. Next, we optimize the initial coarse model to enforce consistency between geometry and appearance (texture images). Then, building details are reconstructed by assembling templates on the textured faces of the coarse model. The 3D templates are automatically chosen and located by our optimization-based template assembly algorithm that balances image matching and structural regularity. In the results, we demonstrate how our framework can enrich the details of coarse models using various data sets.

  20. Exploring Architectural Details Through a Wearable Egocentric Vision Device.

    Science.gov (United States)

    Alletto, Stefano; Abati, Davide; Serra, Giuseppe; Cucchiara, Rita

    2016-02-17

    Augmented user experiences in the cultural heritage domain are in increasing demand by the new digital native tourists of 21st century. In this paper, we propose a novel solution that aims at assisting the visitor during an outdoor tour of a cultural site using the unique first person perspective of wearable cameras. In particular, the approach exploits computer vision techniques to retrieve the details by proposing a robust descriptor based on the covariance of local features. Using a lightweight wearable board, the solution can localize the user with respect to the 3D point cloud of the historical landmark and provide him with information about the details at which he is currently looking. Experimental results validate the method both in terms of accuracy and computational effort. Furthermore, user evaluation based on real-world experiments shows that the proposal is deemed effective in enriching a cultural experience.

  1. Exploring Architectural Details Through a Wearable Egocentric Vision Device

    Directory of Open Access Journals (Sweden)

    Stefano Alletto

    2016-02-01

    Full Text Available Augmented user experiences in the cultural heritage domain are in increasing demand by the new digital native tourists of 21st century. In this paper, we propose a novel solution that aims at assisting the visitor during an outdoor tour of a cultural site using the unique first person perspective of wearable cameras. In particular, the approach exploits computer vision techniques to retrieve the details by proposing a robust descriptor based on the covariance of local features. Using a lightweight wearable board, the solution can localize the user with respect to the 3D point cloud of the historical landmark and provide him with information about the details at which he is currently looking. Experimental results validate the method both in terms of accuracy and computational effort. Furthermore, user evaluation based on real-world experiments shows that the proposal is deemed effective in enriching a cultural experience.

  2. Factors Affecting Two Types of Memory Specificity: Particularization of Episodes and Details.

    Science.gov (United States)

    Willén, Rebecca M; Granhag, Pär Anders; Strömwall, Leif A

    2016-01-01

    Memory for repeated events is relevant to legal investigations about repeated occurrences. We investigated how two measures of specificity (number of events referred to and amount of detail reported about the events) were influenced by interviewees' age, number of experienced events, interviewer, perceived unpleasantness, and memory rehearsal. Transcribed narratives consisting of over 40.000 utterances from 95 dental patients, and the corresponding dental records, were studied. Amount of detail was measured by categorizing the utterances as generic, specific, or specific-extended. We found that the two measures were affected differently by all five factors. For instance, number of experienced events positively influenced number of referred events but had no effect on amount of detail provided about the events. We make suggestions for future research and encourage reanalysis of the present data set and reuse of the material.

  3. Factors Affecting Two Types of Memory Specificity: Particularization of Episodes and Details.

    Directory of Open Access Journals (Sweden)

    Rebecca M Willén

    Full Text Available Memory for repeated events is relevant to legal investigations about repeated occurrences. We investigated how two measures of specificity (number of events referred to and amount of detail reported about the events were influenced by interviewees' age, number of experienced events, interviewer, perceived unpleasantness, and memory rehearsal. Transcribed narratives consisting of over 40.000 utterances from 95 dental patients, and the corresponding dental records, were studied. Amount of detail was measured by categorizing the utterances as generic, specific, or specific-extended. We found that the two measures were affected differently by all five factors. For instance, number of experienced events positively influenced number of referred events but had no effect on amount of detail provided about the events. We make suggestions for future research and encourage reanalysis of the present data set and reuse of the material.

  4. A detailed study of the generation of optically detectable watermarks using the logistic map

    International Nuclear Information System (INIS)

    Mooney, Aidan; Keating, John G.; Heffernan, Daniel M.

    2006-01-01

    A digital watermark is a visible, or preferably invisible, identification code that is permanently embedded in digital media, to prove owner authentication and provide protection for documents. Given the interest in watermark generation using chaotic functions a detailed study of one chaotic function for this purpose is performed. In this paper, we present an approach for the generation of watermarks using the logistic map. Using this function, in conjunction with seed management, it is possible to generate chaotic sequences that may be used to create highpass or lowpass digital watermarks. In this paper we provide a detailed study on the generation of optically detectable watermarks and we provide some guidelines on successful chaotic watermark generation using the logistic map, and show using a recently published scheme, how care must be taken in the selection of the function seed

  5. Template Assembly for Detailed Urban Reconstruction

    KAUST Repository

    Nan, Liangliang; Wonka, Peter; Ghanem, Bernard; Jiang, Caigui

    2015-01-01

    Structure from Motion and Multi View Stereo, and we model a set of 3D templates of facade details. Next, we optimize the initial coarse model to enforce consistency between geometry and appearance (texture images). Then, building details are reconstructed

  6. Capturing Fine Details Involving Low-Cost Sensors -a Comparative Study

    Science.gov (United States)

    Rehany, N.; Barsi, A.; Lovas, T.

    2017-11-01

    Capturing the fine details on the surface of small objects is a real challenge to many conventional surveying methods. Our paper discusses the investigation of several data acquisition technologies, such as arm scanner, structured light scanner, terrestrial laser scanner, object line-scanner, DSLR camera, and mobile phone camera. A palm-sized embossed sculpture reproduction was used as a test object; it has been surveyed by all the instruments. The result point clouds and meshes were then analyzed, using the arm scanner's dataset as reference. In addition to general statistics, the results have been evaluated based both on 3D deviation maps and 2D deviation graphs; the latter allows even more accurate analysis of the characteristics of the different data acquisition approaches. Additionally, own-developed local minimum maps were created that nicely visualize the potential level of detail provided by the applied technologies. Besides the usual geometric assessment, the paper discusses the different resource needs (cost, time, expertise) of the discussed techniques. Our results proved that even amateur sensors operated by amateur users can provide high quality datasets that enable engineering analysis. Based on the results, the paper contains an outlook to potential future investigations in this field.

  7. Detail in architecture: Between arts & crafts

    Science.gov (United States)

    Dulencin, Juraj

    2016-06-01

    Architectural detail represents an important part of architecture. Not only can it be used as an identifier of a specific building but at the same time enhances the experience of the realized project. Within it lie the signs of a great architect and clues to understanding his or her way of thinking. It is therefore the central topic of a seminar offered to architecture students at the Brno University of Technology. During the course of the semester-long class the students acquaint themselves with atypical architectural details of domestic and international architects by learning to read them, understand them and subsequently draw them by creating architectural blueprints. In other words, by general analysis of a detail the students learn theoretical thinking of its architect who, depending on the nature of the design, had to incorporate a variety of techniques and crafts. Students apply this analytical part to their own architectural detail design. The methodology of the seminar consists of experiential learning by project management and is complemented by a series of lectures discussing a diversity of details as well as materials and technologies required to implement it. The architectural detail design is also part of students' bachelors thesis, therefore, the realistic nature of their blueprints can be verified in the production process of its physical counterpart. Based on their own documentation the students choose the most suitable manufacturing process whether it is supplied by a specific technology or a craftsman. Students actively participate in the production and correct their design proposals in real scale with the actual material. A student, as a future architect, stands somewhere between a client and an artisan, materializes his or her idea and adjusts the manufacturing process so that the final detail fulfills aesthetic consistency and is in harmony with its initial concept. One of the very important aspects of the design is its economic cost, an

  8. Detailed inelastic analysis of an LMFBR pipeline

    International Nuclear Information System (INIS)

    Hibbitt, H.D.; Leung, E.K.; Ohalla, A.K.

    1982-01-01

    The paper describes detailed inelastic analyses of a large diameter, thin walled pipeline configuration typical of liquid metal cooled reactor primary piping, subject to thermal shock, with intermediate periods of creep hold time. Three such analyses are compared. Two of these analyses are performed with recently developed elements based on a combination of Fourier and polynomial interpolation to describe the deformation of the pipe. One of these two analyses includes continuous deformation of the pipe wall between each elbow and the adjacent straight pipe segments, while the other neglects such ''end effects'' on the elbow deformation. The third analysis is based on a modified axi-symmetric shell element for modeling the elbows (neglecting and effects). The results thus provide an assessment of the relative cost and importance of including consideration of end effects in modeling a realistic piping system, as well as providing a similar comparison between the two basic deforming section pipe models (Fourier/polynomial versus modified axi-symmetric shells)

  9. Ecolo Watt. Ecologic comparison of electricity providers

    International Nuclear Information System (INIS)

    2007-09-01

    As consumers now can choose their electricity provider, Greenpeace proposes Ecolo Watt, a system which assesses the different providers, more particularly in terms of protection of the environment. This document first describes the electricity market liberalisation (principle, market opening process, a shake-up of the French electric landscape, obligations for the providers). It presents the green electricity market (original guarantees, the questionable system of green certificates, and the Eve label). It describes the methodology adopted for the Ecolo Watt comparative assessment: assessment criteria, final mark. It presents the ranking of electricity providers while analysing their energy mix, their energy policy, their energy service and sales policy, the quality and transparency of information). Detailed results are presented for each operator

  10. A guide to utilization of the microbiology laboratory for diagnosis of infectious diseases: 2013 recommendations by the Infectious Diseases Society of America (IDSA) and the American Society for Microbiology (ASM)(a).

    Science.gov (United States)

    Baron, Ellen Jo; Miller, J Michael; Weinstein, Melvin P; Richter, Sandra S; Gilligan, Peter H; Thomson, Richard B; Bourbeau, Paul; Carroll, Karen C; Kehl, Sue C; Dunne, W Michael; Robinson-Dunn, Barbara; Schwartzman, Joseph D; Chapin, Kimberle C; Snyder, James W; Forbes, Betty A; Patel, Robin; Rosenblatt, Jon E; Pritt, Bobbi S

    2013-08-01

    The critical role of the microbiology laboratory in infectious disease diagnosis calls for a close, positive working relationship between the physician and the microbiologists who provide enormous value to the health care team. This document, developed by both laboratory and clinical experts, provides information on which tests are valuable and in which contexts, and on tests that add little or no value for diagnostic decisions. Sections are divided into anatomic systems, including Bloodstream Infections and Infections of the Cardiovascular System, Central Nervous System Infections, Ocular Infections, Soft Tissue Infections of the Head and Neck, Upper Respiratory Infections, Lower Respiratory Tract infections, Infections of the Gastrointestinal Tract, Intraabdominal Infections, Bone and Joint Infections, Urinary Tract Infections, Genital Infections, and Skin and Soft Tissue Infections; or into etiologic agent groups, including Tickborne Infections, Viral Syndromes, and Blood and Tissue Parasite Infections. Each section contains introductory concepts, a summary of key points, and detailed tables that list suspected agents; the most reliable tests to order; the samples (and volumes) to collect in order of preference; specimen transport devices, procedures, times, and temperatures; and detailed notes on specific issues regarding the test methods, such as when tests are likely to require a specialized laboratory or have prolonged turnaround times. There is redundancy among the tables and sections, as many agents and assay choices overlap. The document is intended to serve as a reference to guide physicians in choosing tests that will aid them to diagnose infectious diseases in their patients.

  11. Executive summary: a guide to utilization of the microbiology laboratory for diagnosis of infectious diseases: 2013 recommendations by the Infectious Diseases Society of America (IDSA) and the American Society for Microbiology (ASM)(a).

    Science.gov (United States)

    Baron, Ellen Jo; Miller, J Michael; Weinstein, Melvin P; Richter, Sandra S; Gilligan, Peter H; Thomson, Richard B; Bourbeau, Paul; Carroll, Karen C; Kehl, Sue C; Dunne, W Michael; Robinson-Dunn, Barbara; Schwartzman, Joseph D; Chapin, Kimberle C; Snyder, James W; Forbes, Betty A; Patel, Robin; Rosenblatt, Jon E; Pritt, Bobbi S

    2013-08-01

    The critical role of the microbiology laboratory in infectious disease diagnosis calls for a close, positive working relationship between the physician and the microbiologists who provide enormous value to the health care team. This document, developed by both laboratory and clinical experts, provides information on which tests are valuable and in which contexts, and on tests that add little or no value for diagnostic decisions. Sections are divided into anatomic systems, including Bloodstream Infections and Infections of the Cardiovascular System, Central Nervous System Infections, Ocular Infections, Soft Tissue Infections of the Head and Neck, Upper Respiratory Infections, Lower Respiratory Tract infections, Infections of the Gastrointestinal Tract, Intraabdominal Infections, Bone and Joint Infections, Urinary Tract Infections, Genital Infections, and Skin and Soft Tissue Infections; or into etiologic agent groups, including Tickborne Infections, Viral Syndromes, and Blood and Tissue Parasite Infections. Each section contains introductory concepts, a summary of key points, and detailed tables that list suspected agents; the most reliable tests to order; the samples (and volumes) to collect in order of preference; specimen transport devices, procedures, times, and temperatures; and detailed notes on specific issues regarding the test methods, such as when tests are likely to require a specialized laboratory or have prolonged turnaround times. There is redundancy among the tables and sections, as many agents and assay choices overlap. The document is intended to serve as a reference to guide physicians in choosing tests that will aid them to diagnose infectious diseases in their patients.

  12. Why healthcare providers merge.

    Science.gov (United States)

    Postma, Jeroen; Roos, Anne-Fleur

    2016-04-01

    In many OECD countries, healthcare sectors have become increasingly concentrated as a result of mergers. However, detailed empirical insight into why healthcare providers merge is lacking. Also, we know little about the influence of national healthcare policies on mergers. We fill this gap in the literature by conducting a survey study on mergers among 848 Dutch healthcare executives, of which 35% responded (resulting in a study sample of 239 executives). A total of 65% of the respondents was involved in at least one merger between 2005 and 2012. During this period, Dutch healthcare providers faced a number of policy changes, including increasing competition, more pressure from purchasers, growing financial risks, de-institutionalisation of long-term care and decentralisation of healthcare services to municipalities. Our empirical study shows that healthcare providers predominantly merge to improve the provision of healthcare services and to strengthen their market position. Also efficiency and financial reasons are important drivers of merger activity in healthcare. We find that motives for merger are related to changes in health policies, in particular to the increasing pressure from competitors, insurers and municipalities.

  13. Practical Approaches for Detecting Selection in Microbial Genomes

    OpenAIRE

    Hedge, Jessica; Wilson, Daniel J.

    2016-01-01

    Microbial genome evolution is shaped by a variety of selective pressures. Understanding how these processes occur can help to address important problems in microbiology by explaining observed differences in phenotypes, including virulence and resistance to antibiotics. Greater access to whole-genome sequencing provides microbiologists with the opportunity to perform large-scale analyses of selection in novel settings, such as within individual hosts. This tutorial aims to guide researchers th...

  14. School Survey on Crime and Safety (SSOCS) 2000 Public-Use Data Files, User's Manual, and Detailed Data Documentation. [CD-ROM].

    Science.gov (United States)

    National Center for Education Statistics (ED), Washington, DC.

    This CD-ROM contains the raw, public-use data from the 2000 School Survey on Crime and Safety (SSOCS) along with a User's Manual and Detailed Data Documentation. The data are provided in SAS, SPSS, STATA, and ASCII formats. The User's Manual and the Detailed Data Documentation are provided as .pdf files. (Author)

  15. Groundwater movements around a repository. Phase 1, State of the art and detailed study plan

    International Nuclear Information System (INIS)

    Lindblom, U.

    1977-02-01

    The report was prepared as the first phase of a study of the groundwater movements around a repository for spent nuclear fuel in the precambrian bedrock of Sweden. The objectives of these studies are to provide a state of the art review of groundwater slow in the region of a repository in granitic rock, in order to provide a basis for long term containment assessments and to prepare a detailed study plan for the continuation of the project. The different processes affecting the groundwater situation for containment are given. A state of the art review of the fluid flow, geochemical, heat transfer and rock mechanics processes as they relate to containment is presented. A detailed study plan to provide a comprehensive assessment of the hydrogeological regime around the repository during its lifetime is also presented. The groundwater flow fields will provide a basis for subsequent long term containment studies. (L.B.)

  16. Characterization and monitoring of host immune responses to infectious agents: what a future for microbiological diagnostics?

    Directory of Open Access Journals (Sweden)

    Riccardo Dolcetti

    2009-06-01

    Full Text Available Our knowledge on the mechanisms underlying microbial pathogenesis and host-microbe interactions has greatly improved over the last decade. In particular, the development of new and specific analytical methods has allowed the detailed characterization of innate and adaptive immune responses against clinically relevant microbial infections. Immunogenetic studies are continuously providing new insights on the genetic bases of individual differences in susceptibility to specific pathogens and most of the genetic markers identified so far include polymorphisms in genes controlling both innate and adaptive immune responses. Moreover, new standardized T cell assays allow reliable and reproducible evaluations of T cell phenotype and functions (i.e.: ELISPOT, including the identification of distinct functional signatures that are associated with the control of the infection.Although the number of these assays currently used in clinical practice is limited, a considerable increase is foreseen for the near future.This perspective constitutes an unprecedented opportunity for Clinical Microbiologists, who may now develop and apply integrated microbiologic/immunologic assays that may be useful for a more precise diagnostic definition and a more accurate clinical monitoring of the disease.

  17. Boosting flood warning schemes with fast emulator of detailed hydrodynamic models

    Science.gov (United States)

    Bellos, V.; Carbajal, J. P.; Leitao, J. P.

    2017-12-01

    Floods are among the most destructive catastrophic events and their frequency has incremented over the last decades. To reduce flood impact and risks, flood warning schemes are installed in flood prone areas. Frequently, these schemes are based on numerical models which quickly provide predictions of water levels and other relevant observables. However, the high complexity of flood wave propagation in the real world and the need of accurate predictions in urban environments or in floodplains hinders the use of detailed simulators. This sets the difficulty, we need fast predictions that meet the accuracy requirements. Most physics based detailed simulators although accurate, will not fulfill the speed demand. Even if High Performance Computing techniques are used (the magnitude of required simulation time is minutes/hours). As a consequence, most flood warning schemes are based in coarse ad-hoc approximations that cannot take advantage a detailed hydrodynamic simulation. In this work, we present a methodology for developing a flood warning scheme using an Gaussian Processes based emulator of a detailed hydrodynamic model. The methodology consists of two main stages: 1) offline stage to build the emulator; 2) online stage using the emulator to predict and generate warnings. The offline stage consists of the following steps: a) definition of the critical sites of the area under study, and the specification of the observables to predict at those sites, e.g. water depth, flow velocity, etc.; b) generation of a detailed simulation dataset to train the emulator; c) calibration of the required parameters (if measurements are available). The online stage is carried on using the emulator to predict the relevant observables quickly, and the detailed simulator is used in parallel to verify key predictions of the emulator. The speed gain given by the emulator allows also to quantify uncertainty in predictions using ensemble methods. The above methodology is applied in real

  18. Process of Integrating Screening and Detailed Risk-based Modeling Analyses to Ensure Consistent and Scientifically Defensible Results

    International Nuclear Information System (INIS)

    Buck, John W.; McDonald, John P.; Taira, Randal Y.

    2002-01-01

    To support cleanup and closure of these tanks, modeling is performed to understand and predict potential impacts to human health and the environment. Pacific Northwest National Laboratory developed a screening tool for the United States Department of Energy, Office of River Protection that estimates the long-term human health risk, from a strategic planning perspective, posed by potential tank releases to the environment. This tool is being conditioned to more detailed model analyses to ensure consistency between studies and to provide scientific defensibility. Once the conditioning is complete, the system will be used to screen alternative cleanup and closure strategies. The integration of screening and detailed models provides consistent analyses, efficiencies in resources, and positive feedback between the various modeling groups. This approach of conditioning a screening methodology to more detailed analyses provides decision-makers with timely and defensible information and increases confidence in the results on the part of clients, regulators, and stakeholders

  19. Escape rate for nonequilibrium processes dominated by strong non-detailed balance force

    Science.gov (United States)

    Tang, Ying; Xu, Song; Ao, Ping

    2018-02-01

    Quantifying the escape rate from a meta-stable state is essential to understand a wide range of dynamical processes. Kramers' classical rate formula is the product of an exponential function of the potential barrier height and a pre-factor related to the friction coefficient. Although many applications of the rate formula focused on the exponential term, the prefactor can have a significant effect on the escape rate in certain parameter regions, such as the overdamped limit and the underdamped limit. There have been continuous interests to understand the effect of non-detailed balance on the escape rate; however, how the prefactor behaves under strong non-detailed balance force remains elusive. In this work, we find that the escape rate formula has a vanishing prefactor with decreasing friction strength under the strong non-detailed balance limit. We both obtain analytical solutions in specific examples and provide a derivation for more general cases. We further verify the result by simulations and propose a testable experimental system of a charged Brownian particle in electromagnetic field. Our study demonstrates that a special care is required to estimate the effect of prefactor on the escape rate when non-detailed balance force dominates.

  20. Equipment for welding of details and joints of plastic pipes in work shop conditions and at pipelines

    International Nuclear Information System (INIS)

    Doronin, V.A.

    1988-01-01

    A range of welding machines for operation in workshop conditions and at pipelines is presented. Set of welding equipment for mobile shop, producing prototypes, and mobile facility are developed. In 1989 they will provide the whole operation cycle of production and mounting of details and units of plastic tubes and will enable to organize the centralized production of welded and shaped details in the branch, thus excluding the shortage of these details. 8 refs.; 6 figs.; 2 tabs

  1. Detailed α -decay study of 180Tl

    Science.gov (United States)

    Andel, B.; Andreyev, A. N.; Antalic, S.; Barzakh, A.; Bree, N.; Cocolios, T. E.; Comas, V. F.; Diriken, J.; Elseviers, J.; Fedorov, D. V.; Fedosseev, V. N.; Franchoo, S.; Ghys, L.; Heredia, J. A.; Huyse, M.; Ivanov, O.; Köster, U.; Liberati, V.; Marsh, B. A.; Nishio, K.; Page, R. D.; Patronis, N.; Seliverstov, M. D.; Tsekhanovich, I.; Van den Bergh, P.; Van De Walle, J.; Van Duppen, P.; Venhart, M.; Vermote, S.; Veselský, M.; Wagemans, C.

    2017-11-01

    A detailed α -decay spectroscopy study of 180Tl has been performed at ISOLDE (CERN). Z -selective ionization by the Resonance Ionization Laser Ion Source (RILIS) coupled to mass separation provided a high-purity beam of 180Tl. Fine-structure α decays to excited levels in the daughter 176Au were identified and an α -decay scheme of 180Tl was constructed based on an analysis of α -γ and α -γ -γ coincidences. Multipolarities of several γ -ray transitions deexciting levels in 176Au were determined. Based on the analysis of reduced α -decay widths, it was found that all α decays are hindered, which signifies a change of configuration between the parent and all daughter states.

  2. Biosafety Education and Training Programs for Ukrainian Microbiologists

    International Nuclear Information System (INIS)

    Pushkina, V.; Volyansky, A.; Popova, N.

    2007-01-01

    In the period of the Soviet Union Ukrainian Mechnikov Anti-Plaque Research Institute was one of the main bases of centralized training for laboratory diagnosis of especially dangerous infections. Not only specialists, but medical technicians were obligatory trained. In training programs special attention was paid to the safety regime in accurate work out of practical manipulations in investigational classical methods (cultivating technique, pipeting, animals' infection and dissection, etc.), protective clothes usage, anti-epidemic measures use at different accidents. This approach gave effective results not only in laboratories but also during field work (natural plaque foci investigations, etc.) and at emergencies. Recently in world practice to increase the level of biosafety technical equipment and devices are developed and used very intensively. During training maximal time is paid to their mastering. At such training biosafety practically depends on safe and reliable work of engineer-technical systems. At present in Ukrainian Anti-Plaque Institute with the support of Canadian Government Training Centre on biosafety and biodefense for specialists of Ukraine and FSU countries is being organized. Teaching programs will include complex study of hand manipulations and modern technical means knowledge. To our mind such initial training had to be available for all specialists of BSL 1-2 microbiological laboratories of any subordination. For this goal all kinds of programs will be developed. Such complex approach will promote to decrease biological risks in microbiological laboratories and prevent infectious agents import from working territories.(author)

  3. Encouraging creativity and employability skills in undergraduate microbiologists.

    Science.gov (United States)

    Verran, Joanna

    2010-02-01

    Key skills such as communication and critical thinking are essential for today's microbiology graduate. There are many opportunities within the undergraduate curriculum to help students to use, develop and appreciate their own unique set of skills. This article describes personal experiences of research-led teaching at Manchester Metropolitan University (UK) which have been used successfully to encourage creativity and other employability skills in both large and smaller classroom settings, and through individual student project work. (c) 2009 Elsevier Ltd. All rights reserved.

  4. AmWeb: a novel interactive web tool for antimicrobial resistance surveillance, applicable to both community and hospital patients.

    Science.gov (United States)

    Ironmonger, Dean; Edeghere, Obaghe; Gossain, Savita; Bains, Amardeep; Hawkey, Peter M

    2013-10-01

    Antimicrobial resistance (AMR) is recognized as one of the most significant threats to human health. Local and regional AMR surveillance enables the monitoring of temporal changes in susceptibility to antibiotics and can provide prescribing guidance to healthcare providers to improve patient management and help slow the spread of antibiotic resistance in the community. There is currently a paucity of routine community-level AMR surveillance information. The HPA in England sponsored the development of an AMR surveillance system (AmSurv) to collate local laboratory reports. In the West Midlands region of England, routine reporting of AMR data has been established via the AmSurv system from all diagnostic microbiology laboratories. The HPA Regional Epidemiology Unit developed a web-enabled database application (AmWeb) to provide microbiologists, pharmacists and other stakeholders with timely access to AMR data using user-configurable reporting tools. AmWeb was launched in the West Midlands in January 2012 and is used by microbiologists and pharmacists to monitor resistance profiles, perform local benchmarking and compile data for infection control reports. AmWeb is now being rolled out to all English regions. It is expected that AmWeb will become a valuable tool for monitoring the threat from newly emerging or currently circulating resistant organisms and helping antibiotic prescribers to select the best treatment options for their patients.

  5. Generation and memory for contextual detail.

    Science.gov (United States)

    Mulligan, Neil W

    2004-07-01

    Generation enhances item memory but may not enhance other aspects of memory. In 12 experiments, the author investigated the effect of generation on context memory, motivated in part by the hypothesis that generation produces a trade-off in encoding item and contextual information. Participants generated some study words (e.g., hot-c__) and read others (e.g., hot-cold). Generation consistently enhanced item memory but did not enhance context memory. More specifically, generation disrupted context memory for the color of the target word but did not affect context memory for location, background color, and cue-word color. The specificity of the negative generation effect in context memory argues against a general item-context trade-off. A processing account of generation meets greater success. In addition, the results provide no evidence that generation enhances recollection of contextual details. Copyright 2004 APA, all rights reserved

  6. Fatigue-Prone Details in Steel Bridges

    Directory of Open Access Journals (Sweden)

    Mohsen Heshmati

    2012-11-01

    Full Text Available This paper reviews the results of a comprehensive investigation including more than 100 fatigue damage cases, reported for steel and composite bridges. The damage cases are categorized according to types of detail. The mechanisms behind fatigue damage in each category are identified and studied. It was found that more than 90% of all reported damage cases are of deformation-induced type and generated by some kind of unintentional or otherwise overlooked interaction between different load-carrying members or systems in the bridge. Poor detailing, with unstiffened gaps and abrupt changes in stiffness at the connections between different members were also found to contribute to fatigue cracking in many details.

  7. Detailed Soils 24K

    Data.gov (United States)

    Kansas Data Access and Support Center — This data set is a digital soil survey and is the most detailed level of soil geographic data developed by the National Cooperative Soil Survey. The information was...

  8. Calibrating Detailed Chemical Analysis of M dwarfs

    Science.gov (United States)

    Veyette, Mark; Muirhead, Philip Steven; Mann, Andrew; Brewer, John; Allard, France; Homeier, Derek

    2018-01-01

    The ability to perform detailed chemical analysis of Sun-like F-, G-, and K-type stars is a powerful tool with many applications including studying the chemical evolution of the Galaxy, assessing membership in stellar kinematic groups, and constraining planet formation theories. Unfortunately, complications in modeling cooler stellar atmospheres has hindered similar analysis of M-dwarf stars. Large surveys of FGK abundances play an important role in developing methods to measure the compositions of M dwarfs by providing benchmark FGK stars that have widely-separated M dwarf companions. These systems allow us to empirically calibrate metallicity-sensitive features in M dwarf spectra. However, current methods to measure metallicity in M dwarfs from moderate-resolution spectra are limited to measuring overall metallicity and largely rely on astrophysical abundance correlations in stellar populations. In this talk, I will discuss how large, homogeneous catalogs of precise FGK abundances are crucial to advancing chemical analysis of M dwarfs beyond overall metallicity to direct measurements of individual elemental abundances. I will present a new method to analyze high-resolution, NIR spectra of M dwarfs that employs an empirical calibration of synthetic M dwarf spectra to infer effective temperature, Fe abundance, and Ti abundance. This work is a step toward detailed chemical analysis of M dwarfs at a similar precision achieved for FGK stars.

  9. Crowdsourcing detailed flood data

    Science.gov (United States)

    Walliman, Nicholas; Ogden, Ray; Amouzad*, Shahrzhad

    2015-04-01

    Over the last decade the average annual loss across the European Union due to flooding has been 4.5bn Euros, but increasingly intense rainfall, as well as population growth, urbanisation and the rising costs of asset replacements, may see this rise to 23bn Euros a year by 2050. Equally disturbing are the profound social costs to individuals, families and communities which in addition to loss of lives include: loss of livelihoods, decreased purchasing and production power, relocation and migration, adverse psychosocial effects, and hindrance of economic growth and development. Flood prediction, management and defence strategies rely on the availability of accurate information and flood modelling. Whilst automated data gathering (by measurement and satellite) of the extent of flooding is already advanced it is least reliable in urban and physically complex geographies where often the need for precise estimation is most acute. Crowdsourced data of actual flood events is a potentially critical component of this allowing improved accuracy in situations and identifying the effects of local landscape and topography where the height of a simple kerb, or discontinuity in a boundary wall can have profound importance. Mobile 'App' based data acquisition using crowdsourcing in critical areas can combine camera records with GPS positional data and time, as well as descriptive data relating to the event. This will automatically produce a dataset, managed in ArcView GIS, with the potential for follow up calls to get more information through structured scripts for each strand. Through this local residents can provide highly detailed information that can be reflected in sophisticated flood protection models and be core to framing urban resilience strategies and optimising the effectiveness of investment. This paper will describe this pioneering approach that will develop flood event data in support of systems that will advance existing approaches such as developed in the in the UK

  10. A detailed cost analysis of in vitro fertilization and intracytoplasmic sperm injection treatment.

    NARCIS (Netherlands)

    Bouwmans, C.A.; Lintsen, A.M.E.; Eijkemans, M.J.; Habbema, J.D.F.; Braat, D.D.M.; Hakkaart, L.

    2008-01-01

    OBJECTIVE: To provide detailed information about costs of in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) treatment stages and to estimate the cost per IVF and ICSI treatment cycle and ongoing pregnancy. DESIGN: Descriptive micro-costing study. SETTING: Four Dutch IVF

  11. Recovering and Preventing Loss of Detailed Memory: Differential Rates of Forgetting for Detail Types in Episodic Memory

    Science.gov (United States)

    Sekeres, Melanie J.; Bonasia, Kyra; St-Laurent, Marie; Pishdadian, Sara; Winocur, Gordon; Grady, Cheryl; Moscovitch, Morris

    2016-01-01

    Episodic memories undergo qualitative changes with time, but little is known about how different aspects of memory are affected. Different types of information in a memory, such as perceptual detail, and central themes, may be lost at different rates. In patients with medial temporal lobe damage, memory for perceptual details is severely impaired,…

  12. Integration of snow management practices into a detailed snow pack model

    Science.gov (United States)

    Spandre, Pierre; Morin, Samuel; Lafaysse, Matthieu; Lejeune, Yves; François, Hugues; George-Marcelpoil, Emmanuelle

    2016-04-01

    The management of snow on ski slopes is a key socio-economic and environmental issue in mountain regions. Indeed the winter sports industry has become a very competitive global market although this economy remains particularly sensitive to weather and snow conditions. The understanding and implementation of snow management in detailed snowpack models is a major step towards a more realistic assessment of the evolution of snow conditions in ski resorts concerning past, present and future climate conditions. Here we describe in a detailed manner the integration of snow management processes (grooming, snowmaking) into the snowpack model Crocus (Spandre et al., Cold Reg. Sci. Technol., in press). The effect of the tiller is explicitly taken into account and its effects on snow properties (density, snow microstructure) are simulated in addition to the compaction induced by the weight of the grooming machine. The production of snow in Crocus is carried out with respect to specific rules and current meteorological conditions. Model configurations and results are described in detail through sensitivity tests of the model of all parameters related to snow management processes. In-situ observations were carried out in four resorts in the French Alps during the 2014-2015 winter season considering for each resort natural, groomed only and groomed plus snowmaking conditions. The model provides realistic simulations of the snowpack properties with respect to these observations. The main uncertainty pertains to the efficiency of the snowmaking process. The observed ratio between the mass of machine-made snow on ski slopes and the water mass used for production was found to be lower than was expected from the literature, in every resort. The model now referred to as "Crocus-Resort" has been proven to provide realistic simulations of snow conditions on ski slopes and may be used for further investigations. Spandre, P., S. Morin, M. Lafaysse, Y. Lejeune, H. François and E. George

  13. Making detailed predictions makes (some) predictions worse

    Science.gov (United States)

    Kelly, Theresa F.

    In this paper, we investigate whether making detailed predictions about an event makes other predictions worse. Across 19 experiments, 10,895 participants, and 415,960 predictions about 724 professional sports games, we find that people who made detailed predictions about sporting events (e.g., how many hits each baseball team would get) made worse predictions about more general outcomes (e.g., which team would win). We rule out that this effect is caused by inattention or fatigue, thinking too hard, or a differential reliance on holistic information about the teams. Instead, we find that thinking about game-relevant details before predicting winning teams causes people to give less weight to predictive information, presumably because predicting details makes information that is relatively useless for predicting the winning team more readily accessible in memory and therefore incorporated into forecasts. Furthermore, we show that this differential use of information can be used to predict what kinds of games will and will not be susceptible to the negative effect of making detailed predictions.

  14. Radioactive contamination mapping system detailed design report

    International Nuclear Information System (INIS)

    Bauer, R.G.; O'Callaghan, P.B.

    1996-08-01

    The Hanford Site's 100 Area production reactors released radioactively and chemically contaminated liquids into the soil column. The primary source of the contaminated liquids was reactor coolant and various waste waters released from planned liquid discharges, as well as pipelines, pipe junctions, and retention basins leaking into the disposal sites. Site remediation involves excavating the contaminated soils using conventional earthmoving techniques and equipment, treating as appropriate, transporting the soils, and disposing the soils at ERDF. To support remediation excavation, disposal, and documentation requirements, an automated radiological monitoring system was deemed necessary. The RCMS (Radioactive Contamination Mapping System) was designed to fulfill this need. This Detailed Design Report provides design information for the RCMS in accordance with Bechtel Hanford, Inc. Engineering Design Project Instructions

  15. The detailed balance requirement and general empirical formalisms for continuum absorption

    Science.gov (United States)

    Ma, Q.; Tipping, R. H.

    1994-01-01

    Two general empirical formalisms are presented for the spectral density which take into account the deviations from the Lorentz line shape in the wing regions of resonance lines. These formalisms satisfy the detailed balance requirement. Empirical line shape functions, which are essential to provide the continuum absorption at different temperatures in various frequency regions for atmospheric transmission codes, can be obtained by fitting to experimental data.

  16. Investigating the Interaction of Graphic Organizers and Seductive Details: Can a Graphic Organizer Mitigate the Seductive-Details Effect?

    Science.gov (United States)

    Rowland-Bryant, Emily; Skinner, Christopher H.; Skinner, Amy L.; Saudargas, Richard; Robinson, Daniel H.; Kirk, Emily R.

    2009-01-01

    The interaction between seductive details (SD) and a graphic organizer (GO) was investigated. Undergraduate students (n = 207) read a target-material passage about Freud's psychosexual stages. Depending on condition, the participants also read a biographical paragraph (SD-only), viewed a graphic organizer that linked the seductive details to the…

  17. Key Features of Academic Detailing: Development of an Expert Consensus Using the Delphi Method.

    Science.gov (United States)

    Yeh, James S; Van Hoof, Thomas J; Fischer, Michael A

    2016-02-01

    Academic detailing is an outreach education technique that combines the direct social marketing traditionally used by pharmaceutical representatives with unbiased content summarizing the best evidence for a given clinical issue. Academic detailing is conducted with clinicians to encourage evidence-based practice in order to improve the quality of care and patient outcomes. The adoption of academic detailing has increased substantially since the original studies in the 1980s. However, the lack of standard agreement on its implementation makes the evaluation of academic detailing outcomes challenging. To identify consensus on the key elements of academic detailing among a group of experts with varying experiences in academic detailing. This study is based on an online survey of 20 experts with experience in academic detailing. We used the Delphi process, an iterative and systematic method of developing consensus within a group. We conducted 3 rounds of online surveys, which addressed 72 individual items derived from a previous literature review of 5 features of academic detailing, including (1) content, (2) communication process, (3) clinicians targeted, (4) change agents delivering intervention, and (5) context for intervention. Nonrespondents were removed from later rounds of the surveys. For most questions, a 4-point ordinal scale was used for responses. We defined consensus agreement as 70% of respondents for a single rating category or 80% for dichotomized ratings. The overall survey response rate was 95% (54 of 57 surveys) and nearly 92% consensus agreement on the survey items (66 of 72 items) by the end of the Delphi exercise. The experts' responses suggested that (1) focused clinician education offering support for clinical decision-making is a key component of academic detailing, (2) detailing messages need to be tailored and provide feasible strategies and solutions to challenging cases, and (3) academic detailers need to develop specific skill sets

  18. Performance evaluation of contrast-detail in full field digital mammography systems using ideal (Hotelling) observer vs. conventional automated analysis of CDMAM images for quality control of contrast-detail characteristics.

    Science.gov (United States)

    Delakis, Ioannis; Wise, Robert; Morris, Lauren; Kulama, Eugenia

    2015-11-01

    The purpose of this work was to evaluate the contrast-detail performance of full field digital mammography (FFDM) systems using ideal (Hotelling) observer Signal-to-Noise Ratio (SNR) methodology and ascertain whether it can be considered an alternative to the conventional, automated analysis of CDMAM phantom images. Five FFDM units currently used in the national breast screening programme were evaluated, which differed with respect to age, detector, Automatic Exposure Control (AEC) and target/filter combination. Contrast-detail performance was analysed using CDMAM and ideal observer SNR methodology. The ideal observer SNR was calculated for input signal originating from gold discs of varying thicknesses and diameters, and then used to estimate the threshold gold thickness for each diameter as per CDMAM analysis. The variability of both methods and the dependence of CDMAM analysis on phantom manufacturing discrepancies also investigated. Results from both CDMAM and ideal observer methodologies were informative differentiators of FFDM systems' contrast-detail performance, displaying comparable patterns with respect to the FFDM systems' type and age. CDMAM results suggested higher threshold gold thickness values compared with the ideal observer methodology, especially for small-diameter details, which can be attributed to the behaviour of the CDMAM phantom used in this study. In addition, ideal observer methodology results showed lower variability than CDMAM results. The Ideal observer SNR methodology can provide a useful metric of the FFDM systems' contrast detail characteristics and could be considered a surrogate for conventional, automated analysis of CDMAM images. Copyright © 2015 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.

  19. Technology-enabled academic detailing: computer-mediated education between pharmacists and physicians for evidence-based prescribing.

    Science.gov (United States)

    Ho, Kendall; Nguyen, Anne; Jarvis-Selinger, Sandra; Novak Lauscher, Helen; Cressman, Céline; Zibrik, Lindsay

    2013-09-01

    recruitment was very low for the cross over groups, we analyzed the results in two groups instead: AD only and TEAD only. 354 sessions were conducted (AD=161, TEAD=193). Of these, complete data were available for 300 sessions, which were included in analysis (AD=133, TEAD=167). On average, TEAD sessions were 49min long, and AD sessions 81min long. Overall, physicians enjoyed both modalities of academic detailing (AD and TEAD) because they received information that both reinforced their existing diabetes knowledge and also provided new prescribing insights and approaches. The results suggest that TEAD is an acceptable alternative to AD for providing physicians advice about prescribing. TEAD is more time efficient, facilitates effective knowledge exchange and interprofessional collaboration, and can reach those physicians virtually where face-to-face AD is not possible or practical. Due to logistics, physicians were allocated, rather than randomized, to receive AD and/or TEAD. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

  20. External details revisited - A new taxonomy for coding 'non-episodic' content during autobiographical memory retrieval.

    Science.gov (United States)

    Strikwerda-Brown, Cherie; Mothakunnel, Annu; Hodges, John R; Piguet, Olivier; Irish, Muireann

    2018-04-24

    Autobiographical memory (ABM) is typically held to comprise episodic and semantic elements, with the vast majority of studies to date focusing on profiles of episodic details in health and disease. In this context, 'non-episodic' elements are often considered to reflect semantic processing or are discounted from analyses entirely. Mounting evidence suggests that rather than reflecting one unitary entity, semantic autobiographical information may contain discrete subcomponents, which vary in their relative degree of semantic or episodic content. This study aimed to (1) review the existing literature to formally characterize the variability in analysis of 'non-episodic' content (i.e., external details) on the Autobiographical Interview and (2) use these findings to create a theoretically grounded framework for coding external details. Our review exposed discrepancies in the reporting and interpretation of external details across studies, reinforcing the need for a new, consistent approach. We validated our new external details scoring protocol (the 'NExt' taxonomy) in patients with Alzheimer's disease (n = 18) and semantic dementia (n = 13), and 20 healthy older Control participants and compared profiles of the NExt subcategories across groups and time periods. Our results revealed increased sensitivity of the NExt taxonomy in discriminating between ABM profiles of patient groups, when compared to traditionally used internal and external detail metrics. Further, remote and recent autobiographical memories displayed distinct compositions of the NExt detail types. This study is the first to provide a fine-grained and comprehensive taxonomy to parse external details into intuitive subcategories and to validate this protocol in neurodegenerative disorders. © 2018 The British Psychological Society.

  1. Kinetic energy budget details

    Indian Academy of Sciences (India)

    Abstract. This paper presents the detailed turbulent kinetic energy budget and higher order statistics of flow behind a surface-mounted rib with and without superimposed acoustic excitation. Pattern recognition technique is used to determine the large-scale structure magnitude. It is observed that most of the turbulence ...

  2. A new debate for Turkish physicians: e-detailing.

    Science.gov (United States)

    Ventura, Keti; Baybars, Miray; Dedeoglu, Ayla Ozhan

    2012-01-01

    The study presents an empirical analysis of the attitudes of Turkish physicians towards e-detailing practices compared to face-to-face detailing. The findings reveal that although physicians have positive attitudes toward e-detailing, on some points they are still undecided and/or have doubts. The structural model revealed that affect, convenience, and informative content influence their attitude in a positive manner, whereas the personal interaction was found to be a negative factor. Physicians' age and frequency of calls received from representatives are moderators. The present study can be seen as an addition to pharmaceutical marketing, an underresearched study field in Turkey, and e-detailing particularly.

  3. Impacts of Outer Continental Shelf (OCS) development on recreation and tourism. Volume 3. Detailed methodology

    Energy Technology Data Exchange (ETDEWEB)

    1987-04-01

    The final report for the project is presented in five volumes. This volume, Detailed Methodology Review, presents a discussion of the methods considered and used to estimate the impacts of Outer Continental Shelf (OCS) oil and gas development on coastal recreation in California. The purpose is to provide the Minerals Management Service with data and methods to improve their ability to analyze the socio-economic impacts of OCS development. Chapter II provides a review of previous attempts to evaluate the effects of OCS development and of oil spills on coastal recreation. The review also discusses the strengths and weaknesses of different approaches and presents the rationale for the methodology selection made. Chapter III presents a detailed discussion of the methods actually used in the study. The volume contains the bibliography for the entire study.

  4. Perspectives on Providing And Receiving Preventive Health Care From Primary Care Providers and Their Patients With Mental Illnesses.

    Science.gov (United States)

    Stumbo, Scott P; Yarborough, Bobbi Jo H; Yarborough, Micah T; Green, Carla A

    2018-01-01

    Individuals with mental illnesses have higher morbidity rates and reduced life expectancy compared to the general population. Understanding how patients and providers perceive the need for prevention, as well as the barriers and beliefs that may contribute to insufficient care, are important for improving service delivery tailored to this population. Cross-sectional; mixed methods. An integrated health system and a network of federally qualified health centers and safety net clinics. Interviews (n = 30) and surveys (n = 249) with primary care providers. Interviews (n = 158) and surveys (n = 160) with patients diagnosed with schizophrenia, bipolar, anxiety, or major depressive disorders. Semi-structured interviews and surveys. Thematic analysis for qualitative data; frequencies for quantitative data. More than half (n = 131, 53%) of clinicians believed patients with mental illnesses care less about preventive care than the general population, yet 88% (n = 139) of patients reported interest in improving health. Most providers (n = 216, 88%) lacked confidence that patients with mental illnesses would follow preventive recommendations; 82% (n = 129) of patients reported they would try to change lifestyles if their doctor recommended. Clinicians explained that their perception of patients' chaotic lives and lack of interest in preventive care contributed to their fatalistic attitudes on care delivery to this population. Clinicians and patients agreed on substantial need for additional support for behavior changes. Clinicians reported providing informational support by keeping messages simple; patients reported a desire for more detailed information on reasons to complete preventive care. Patients also detailed the need for assistive and tangible support to manage behavioral health changes. Our results suggest a few clinical changes could help patients complete preventive care recommendations and improve health behaviors: improving clinician-patient collaboration on

  5. Detailed measurements of deformation in the excavation disturbed zone

    International Nuclear Information System (INIS)

    Thompson, P.M.; Martino, J.B.; Spinney, M.H.

    1993-01-01

    An excavation damage extensometer (EDEX) is described. It was designed to enable detailed small-scale deformation measurements to be made in the excavation disturbed zone (EDZ) around a tunnel opening in stressed rock. Its use in the Mine-by Experiment in unfractured granitic rock at the Underground Research Laboratory (Manitoba) is described. The results obtained from an array of eight EDEX installations are presented. These demonstrate how the EDEX can be used to provide data on the EDZ which is supplementary to that obtained by larger scale borehole extensometers and a acoustic emission/micro-seismic monitoring system. (4 figures, 5 references) (UK)

  6. Visual Memory : The Price of Encoding Details

    NARCIS (Netherlands)

    Nieuwenstein, Mark; Kromm, Maria

    2017-01-01

    Studies on visual long-term memory have shown that we have a tremendous capacity for remembering pictures of objects, even at a highly detailed level. What remains unclear, however, is whether encoding objects at such a detailed level comes at any cost. In the current study, we examined how the

  7. Three Latin Phonological Details

    DEFF Research Database (Denmark)

    Olsen, Birgit Anette

    2006-01-01

    The present paper deals with three minor details of Latin phonology: 1) the development of the initial sequence *u¿l¿-, where it is suggested that an apparent vacillation between ul- and vol-/vul- represents sandhi variants going back to the proto-language, 2) the adjectives ama¯rus ‘bitter' and ...

  8. Memory for details with self-referencing.

    Science.gov (United States)

    Serbun, Sarah J; Shih, Joanne Y; Gutchess, Angela H

    2011-11-01

    Self-referencing benefits item memory, but little is known about the ways in which referencing the self affects memory for details. Experiment 1 assessed whether the effects of self-referencing operate only at the item, or general, level or whether they also enhance memory for specific visual details of objects. Participants incidentally encoded objects by making judgements in reference to the self, a close other (one's mother), or a familiar other (Bill Clinton). Results indicate that referencing the self or a close other enhances both specific and general memory. Experiments 2 and 3 assessed verbal memory for source in a task that relied on distinguishing between different mental operations (internal sources). The results indicate that self-referencing disproportionately enhances source memory, relative to conditions referencing other people, semantic, or perceptual information. We conclude that self-referencing not only enhances specific memory for both visual and verbal information, but can also disproportionately improve memory for specific internal source details.

  9. Detailed description of an SSAC at the facility level for a low-enriched uranium conversion and fuel fabrication facility

    International Nuclear Information System (INIS)

    Jones, R.J.

    1984-09-01

    Some States have expressed a need for more detailed guidance with regard to the technical elements in the design and operation of SSACs for both the national and the international objectives. To meet this need the present document has been prepared, describing the technical elements of an SSAC in considerable detail. The purpose of this document is therefore, to provide a detailed description of a system for the accounting for and control of nuclear material in a model low enriched uranium conversion and fuel fabrication facility which can be used by a facility operator to establish his own system in a way which will provide the necessary information for compliance with a national system for nuclear material accounting and control and for the IAEA to carry out its safeguards responsibilities

  10. The need for European professional standards and the challenges facing clinical microbiology.

    Science.gov (United States)

    Humphreys, H; Nagy, E; Kahlmeter, G; Ruijs, G J H M

    2010-06-01

    Microorganisms spread across national boundaries and the professional activities of clinical (medical) microbiologists are critical in minimising their impact. Clinical microbiologists participate in many activities, e.g. diagnosis, antibiotic therapy, and there is a need for a set of professional standards for Europe with a common curriculum, to build upon the current strengths of the specialty and to facilitate the free movement of specialists within the European Union. Such standards will also better highlight the important contribution of clinical microbiologists to healthcare. There is a move to larger centralised microbiology laboratories often located off-site from an acute hospital, driven by the concentration of resources, amalgamation of services, outsourcing of diagnostics, automation, an explosion in the range of staff competencies and accreditation. Large off-site centralised microbiology laboratories are often distant to the patient and may not facilitate the early detection of microbial spread. Ultimately, the needs of patients and the public are paramount in deciding on the future direction of clinical microbiology. Potential conflicts between integration on an acute hospital site and centralisation can be resolved by a common set of professional standards and a team-based approach that puts patients first.

  11. Generalized detailed balance theory of solar cells

    Energy Technology Data Exchange (ETDEWEB)

    Kirchartz, Thomas

    2009-12-12

    The principle of detailed balance is the requirement that every microscopic process in a system must be in equilibrium with its inverse process, when the system itself is in thermodynamic equilibrium. This detailed balance principle has been of special importance for photovoltaics, since it allows the calculation of the limiting efficiency of a given solar cell by defining the only fundamental loss process as the radiative recombination of electron/hole pairs followed by the emission of a photon. In equilibrium, i.e. in the dark and without applied voltage, the absorbed and emitted photon flux must be equal due to detailed balance. This equality determines the radiative recombination from absorption and vice versa. While the classical theory of photovoltaic efficiency limits by Shockley and Queisser considers only one detailed balance pair, namely photogeneration and radiative recombination, the present work extends the detailed balance principle to any given process in the solar cell. Applying the detailed balance principle to the whole device leads to two major results, namely (i) a model that is compatible with the Shockley-Queisser efficiency limit for efficient particle transport, while still being able to describe non-ideal and non-linear solar cells, and (ii) an analytical relation between electroluminescent emission and photovoltaic action of a diode that is applied to a variety of different solar cells. This thesis presents several variations of a detailed balance model that are applicable to different types of solar cells. Any typical inorganic solar cell is a mainly bipolar device, meaning that the current is carried by electrons and holes. The detailed balance model for pn-type and pin-type bipolar solar cells is therefore the most basic incorporation of a detailed balance model. The only addition compared to the classical diode theory or compared to standard one-dimensional device simulators is the incorporation of photon recycling, making the model

  12. Detailed oil spill contingency analysis in establishment of preparedness plans for exploration drilling in environmentally sensitive areas: an integrated management process

    Energy Technology Data Exchange (ETDEWEB)

    Spikkerud, Cathrine S.; Skeie, Geir Morten; Brude, Odd Willy; Gravir, Gjermund [DNV Managing Risk, Oslo (Norway)

    2008-07-01

    This paper describes the integrated management process leading up to a dynamic oil spill preparedness plan based on detailed analysis of oil spill contingency requirements and environmental risk in environmentally sensitive areas. Starting with a detailed environmental risk and oil spill contingency analysis, oil spill preparedness plans are developed. These plans are generic for the area possibly affected by an oil spill, and are developed in detail for environmental 'hot spots' that are highly challenging in terms of oil spill response. The detailed plans make use of detailed data sets on shoreline substrate sensitivities and cleanup methodology, photographic inventory, logistical issues and access to real-time incident data for important areas. This detailed approach ensures sufficient knowledge about the sensitive area in advance to provide fast and correct strategic and tactical operational recovery decisions. A final element of the integrated process is a web based GIS, providing all parties involved with one common situation overview, ensuring that the facts remain in focus throughout the operation and that those responsible for informing stake-holders have access to correct and timely updated information. (author)

  13. Older adults report moderately more detailed autobiographical memories.

    Science.gov (United States)

    Gardner, Robert S; Mainetti, Matteo; Ascoli, Giorgio A

    2015-01-01

    Autobiographical memory (AM) is an essential component of the human mind. Although the([A-z]+) amount and types of subjective detail (content) that compose AMs constitute important dimensions of recall, age-related changes in memory content are not well characterized. Previously, we introduced the Cue-Recalled Autobiographical Memory test (CRAM; see http://cramtest.info), an instrument that collects subjective reports of AM content, and applied it to college-aged subjects. CRAM elicits AMs using naturalistic word-cues. Subsequently, subjects date each cued AM to a life period and count the number of remembered details from specified categories (features), e.g., temporal detail, spatial detail, persons, objects, and emotions. The current work applies CRAM to a broad range of individuals (18-78 years old) to quantify the effects of age on AM content. Subject age showed a moderately positive effect on AM content: older compared with younger adults reported ∼16% more details (∼25 vs. ∼21 in typical AMs). This age-related increase in memory content was similarly observed for remote and recent AMs, although content declined with the age of the event among all subjects. In general, the distribution of details across features was largely consistent among younger and older adults. However, certain types of details, i.e., those related to objects and sequences of events, contributed more to the age effect on content. Altogether, this work identifies a moderate age-related feature-specific alteration in the way life events are subjectively recalled, among an otherwise stable retrieval profile.

  14. Older adults report moderately more detailed autobiographical memories

    Directory of Open Access Journals (Sweden)

    Robert S Gardner

    2015-05-01

    Full Text Available Autobiographical memory (AM is an essential component of the human mind. Although the amount and types of subjective detail (content that compose AMs constitute important dimensions of recall, age-related changes in memory content are not well characterized. Previously, we introduced the Cue-Recalled Autobiographical Memory test (CRAM; see http://cramtest.info, an instrument that collects subjective reports of AM content, and applied it to college-aged subjects. CRAM elicits AMs using naturalistic word-cues. Subsequently, subjects date each cued AM to a life period and count the number of remembered details from specified categories (features, e.g., temporal detail, spatial detail, persons, objects, and emotions. The current work applies CRAM to a broad range of individuals (18-78 years old to quantify the effects of age on AM content. Subject age showed a moderately positive effect on AM content: older compared with younger adults reported ~16% more details (~25 vs. ~21 in typical AMs. This age-related increase in memory content was similarly observed for remote and recent AMs, although content declined with the age of the event among all subjects. In general, the distribution of details across features was largely consistent among younger and older adults. However, certain types of details, i.e., those related to objects and sequences of events, contributed more to the age effect on content. Altogether, this work identifies a moderate age-related feature-specific alteration in the way life events are subjectively recalled, among an otherwise stable retrieval profile.

  15. Local address and emergency contact details

    CERN Multimedia

    2013-01-01

    The HR Department would like to remind members of the personnel that they are responsible for ensuring that their personal data concerning local address and preferred emergency contact details remains valid and up-to-date.   Both are easily accessible via the links below: Local address: https://edh.cern.ch/Document/Personnel/LocalAddressChange   Emergency contacts: https://edh.cern.ch/Document/Personnel/EC   Please take a few minutes to check your details and modify if necessary. Thank you in advance. HR Department Head Office

  16. Is the truth in the details? Extended narratives help distinguishing false "memories" from false "reports".

    Science.gov (United States)

    Sjödén, Björn; Granhag, Pär Anders; Ost, James; Roos Af Hjelmsäter, Emma

    2009-06-01

    The present study examined the effects of fantasy proneness on false "reports" and false "memories", of existent and non-existent footage of a public event. We predicted that highly fantasy prone individuals would be more likely to stand by their initial claim of having seen a film of the event than low fantasy prone participants when prompted for more details about their experiences. Eighty creative arts students and 80 other students were asked whether they had seen CCTV footage preceding the attack on Swedish foreign minister Anna Lindh up to, and including, non-existent footage of the actual moment of the attack. If affirmative, they were probed for extended narratives of what they claimed to have seen. Overall, 64% of participants provided a false "report" by answering yes to the initial question. Of these, 30% provided no explicit details of the attack, and a further 15% retracted their initial answer in their narratives. This left 19% of the sample who appeared to have false "memories" because they provided explicit details of the actual moment of the attack. Women scored higher than men and art students scored higher than other students on fantasy proneness, but there was no effect on levels of false reporting or false "memory". Memories were rated more vivid and clear for existent compared to non-existent aspects of the event. In sum, these data suggest a more complex relationship between memory distortions and fantasy proneness than previously observed.

  17. Memory's aging echo: age-related decline in neural reactivation of perceptual details during recollection.

    Science.gov (United States)

    McDonough, Ian M; Cervantes, Sasha N; Gray, Stephen J; Gallo, David A

    2014-09-01

    Episodic memory decline is a hallmark of normal cognitive aging. Here, we report the first event-related fMRI study to directly investigate age differences in the neural reactivation of qualitatively rich perceptual details during recollection. Younger and older adults studied pictures of complex scenes at different presentation durations along with descriptive verbal labels, and these labels subsequently were used during fMRI scanning to cue picture recollections of varying perceptual detail. As expected from prior behavioral work, the two age groups subjectively rated their recollections as containing similar amounts of perceptual detail, despite objectively measured recollection impairment in older adults. In both age groups, comparisons of retrieval trials that varied in recollected detail revealed robust activity in brain regions previously linked to recollection, including hippocampus and both medial and lateral regions of the prefrontal and posterior parietal cortex. Critically, this analysis also revealed recollection-related activity in visual processing regions that were active in an independent picture-perception task, and these regions showed age-related reductions in activity during recollection that cannot be attributed to age differences in response criteria. These fMRI findings provide new evidence that aging reduces the absolute quantity of perceptual details that are reactivated from memory, and they help to explain why aging reduces the reliability of subjective memory judgments. Copyright © 2014 Elsevier Inc. All rights reserved.

  18. A model for determining the scope and level of detail that is appropriate for a programmatic EIS

    International Nuclear Information System (INIS)

    Eccleston, C.H.

    1995-03-01

    Since the inception of the National Environmental Policy Act (NEPA), no definitive guidance has been established for determining the scope of topics and issues, or the level of detail suitable for presentation within a Programmatic Environmental Impact Statement (P-EIS). Lacking such guidance, an inordinate amount of time and resources can be expended in determining the scope that is most appropriately addressed within a P-EIS versus the more detailed scope that is best reserved for lower-tier documents. Faced with this predicament, agencies often err on the side of including too much detail, resulting in P-EISs that are over bloated and unnecessarily complex. Moreover, lack of definitive guidance leads to a great deal of inconsistency in the preparation of P-EISs among federal agency programs. A paradigm for assisting decisionmakers in making such determinations is presented below. This model expedites the preparation of P-EISs by providing a consistent and systematic approach for determining the scope and level of detail that is most appropriately addressed at the programmatic level. In many cases, the model provides agencies with an effective tool for managing and streamlining the NEPA process by de-scoping needless and unnecessary issues from the scope of a P-EIS

  19. Look@NanoSIMS--a tool for the analysis of nanoSIMS data in environmental microbiology.

    Science.gov (United States)

    Polerecky, Lubos; Adam, Birgit; Milucka, Jana; Musat, Niculina; Vagner, Tomas; Kuypers, Marcel M M

    2012-04-01

    We describe an open-source freeware programme for high throughput analysis of nanoSIMS (nanometre-scale secondary ion mass spectrometry) data. The programme implements basic data processing and analytical functions, including display and drift-corrected accumulation of scanned planes, interactive and semi-automated definition of regions of interest (ROIs), and export of the ROIs' elemental and isotopic composition in graphical and text-based formats. Additionally, the programme offers new functions that were custom-designed to address the needs of environmental microbiologists. Specifically, it allows manual and automated classification of ROIs based on the information that is derived either from the nanoSIMS dataset itself (e.g. from labelling achieved by halogen in situ hybridization) or is provided externally (e.g. as a fluorescence in situ hybridization image). Moreover, by implementing post-processing routines coupled to built-in statistical tools, the programme allows rapid synthesis and comparative analysis of results from many different datasets. After validation of the programme, we illustrate how these new processing and analytical functions increase flexibility, efficiency and depth of the nanoSIMS data analysis. Through its custom-made and open-source design, the programme provides an efficient, reliable and easily expandable tool that can help a growing community of environmental microbiologists and researchers from other disciplines process and analyse their nanoSIMS data. © 2012 Society for Applied Microbiology and Blackwell Publishing Ltd.

  20. Detailed 3D models of the induced electric field of transcranial magnetic stimulation coils

    Energy Technology Data Exchange (ETDEWEB)

    Salinas, F S; Lancaster, J L; Fox, P T [Research Imaging Center, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229 (United States)

    2007-05-21

    Previous models neglected contributions from current elements spanning the full geometric extent of wires in transcranial magnetic stimulation (TMS) coils. A detailed account of TMS coil wiring geometry is shown to provide significant improvements in the accuracy of electric field (E-field) models. Modeling E-field dependence based on the TMS coil's wire width, height, shape and number of turns clearly improved the fit of calculated-to-measured E-fields near the coil body. Detailed E-field models were accurate up to the surface of the coil body (within 0.5% of measured) where simple models were often inadequate (up to 32% different from measured)

  1. Detailed 3D models of the induced electric field of transcranial magnetic stimulation coils

    International Nuclear Information System (INIS)

    Salinas, F S; Lancaster, J L; Fox, P T

    2007-01-01

    Previous models neglected contributions from current elements spanning the full geometric extent of wires in transcranial magnetic stimulation (TMS) coils. A detailed account of TMS coil wiring geometry is shown to provide significant improvements in the accuracy of electric field (E-field) models. Modeling E-field dependence based on the TMS coil's wire width, height, shape and number of turns clearly improved the fit of calculated-to-measured E-fields near the coil body. Detailed E-field models were accurate up to the surface of the coil body (within 0.5% of measured) where simple models were often inadequate (up to 32% different from measured)

  2. GIS-assisted spatial analysis for urban regulatory detailed planning: designer's dimension in the Chinese code system

    Science.gov (United States)

    Yu, Yang; Zeng, Zheng

    2009-10-01

    By discussing the causes behind the high amendments ratio in the implementation of urban regulatory detailed plans in China despite its law-ensured status, the study aims to reconcile conflict between the legal authority of regulatory detailed planning and the insufficient scientific support in its decision-making and compilation by introducing into the process spatial analysis based on GIS technology and 3D modeling thus present a more scientific and flexible approach to regulatory detailed planning in China. The study first points out that the current compilation process of urban regulatory detailed plan in China employs mainly an empirical approach which renders it constantly subjected to amendments; the study then discusses the need and current utilization of GIS in the Chinese system and proposes the framework of a GIS-assisted 3D spatial analysis process from the designer's perspective which can be regarded as an alternating processes between the descriptive codes and physical design in the compilation of regulatory detailed planning. With a case study of the processes and results from the application of the framework, the paper concludes that the proposed framework can be an effective instrument which provides more rationality, flexibility and thus more efficiency to the compilation and decision-making process of urban regulatory detailed plan in China.

  3. A structurally detailed finite element human head model for simulation of transcranial magnetic stimulation.

    Science.gov (United States)

    Chen, Ming; Mogul, David Jeffery

    2009-04-30

    Computational studies of the head utilizing finite element models (FEMs) have been used to investigate a wide variety of brain-electromagnetic (EM) field interaction phenomena including magnetic stimulation of the head using transcranial magnetic stimulation (TMS), direct electric stimulation of the brain for electroconvulsive therapy, and electroencephalography source localization. However, no human head model of sufficient complexity for studying the biophysics under these circumstances has been developed which utilizes structures at both the regional and cellular levels and provides well-defined smooth boundaries between tissues of different conductivities and orientations. The main barrier for building such accurate head models is the complex modeling procedures that include 3D object reconstruction and optimized meshing. In this study, a structurally detailed finite element model of the human head was generated that includes details to the level of cerebral gyri and sulci by combining computed tomography and magnetic resonance images. Furthermore, cortical columns that contain conductive processes of pyramidal neurons traversing the neocortical layers were included in the head model thus providing structure at or near the cellular level. These refinements provide a much more realistic model to investigate the effects of TMS on brain electrophysiology in the neocortex.

  4. Review of the International Thermonuclear Experimental Reactor (ITER) detailed design report

    International Nuclear Information System (INIS)

    1997-01-01

    Dr. Martha Krebs, Director, Office of Energy Research at the US Department of Energy (DOE), wrote to the Fusion Energy Sciences Advisory Committee (FESAC), in letters dated September 23 and November 6, 1996, requesting that FESAC review the International Thermonuclear Experimental Reactor (ITER) Detailed Design Report (DDR) and provide its view of the adequacy of the DDR as part of the basis for the United States decision to enter negotiations with the other interested Parties regarding the terms and conditions for an agreement for the construction, operations, exploitation and decommissioning of ITER. The letter from Dr. Krebs, referred to as the Charge Letter, provided context for the review and a set of questions of specific interest

  5. Review of the International Thermonuclear Experimental Reactor (ITER) detailed design report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-04-18

    Dr. Martha Krebs, Director, Office of Energy Research at the US Department of Energy (DOE), wrote to the Fusion Energy Sciences Advisory Committee (FESAC), in letters dated September 23 and November 6, 1996, requesting that FESAC review the International Thermonuclear Experimental Reactor (ITER) Detailed Design Report (DDR) and provide its view of the adequacy of the DDR as part of the basis for the United States decision to enter negotiations with the other interested Parties regarding the terms and conditions for an agreement for the construction, operations, exploitation and decommissioning of ITER. The letter from Dr. Krebs, referred to as the Charge Letter, provided context for the review and a set of questions of specific interest.

  6. Understanding brains: details, intuition, and big data.

    Science.gov (United States)

    Marder, Eve

    2015-05-01

    Understanding how the brain works requires a delicate balance between the appreciation of the importance of a multitude of biological details and the ability to see beyond those details to general principles. As technological innovations vastly increase the amount of data we collect, the importance of intuition into how to analyze and treat these data may, paradoxically, become more important.

  7. Understanding Brains: Details, Intuition, and Big Data

    OpenAIRE

    Marder, Eve

    2015-01-01

    Understanding how the brain works requires a delicate balance between the appreciation of the importance of a multitude of biological details and the ability to see beyond those details to general principles. As technological innovations vastly increase the amount of data we collect, the importance of intuition into how to analyze and treat these data may, paradoxically, become more important.

  8. Understanding brains: details, intuition, and big data.

    Directory of Open Access Journals (Sweden)

    Eve Marder

    2015-05-01

    Full Text Available Understanding how the brain works requires a delicate balance between the appreciation of the importance of a multitude of biological details and the ability to see beyond those details to general principles. As technological innovations vastly increase the amount of data we collect, the importance of intuition into how to analyze and treat these data may, paradoxically, become more important.

  9. Development of a system to provide diagnostics-while-drilling.

    Energy Technology Data Exchange (ETDEWEB)

    Wise, Jack LeRoy; Jacobson, Ronald David; Finger, John Travis; Mansure, Arthur James; Knudsen, Steven Dell

    2003-06-01

    This report describes development of a system that provides high-speed, real-time downhole data while drilling. Background of the project, its benefits, major technical challenges, test planning, and test results are covered by relatively brief descriptions in the body of the report, with some topics presented in more detail in the attached appendices.

  10. Presentations provided

    International Nuclear Information System (INIS)

    Hashemian, H.; Beverly, D.

    1998-01-01

    The following topics covered in detail at the workshop included: temperature instrumentation; pressure instrumentation; in-situ calibration and response time testing of RTDs and pressure transmitters; on-line performance monitoring and preventive maintenance of critical equipment; automated measurement of critical parameters; nuclear power plant infrastructure, management and Quality Assurance issues and recent developments for WWER and RBMK reactors. Conclusions drawn were: aging can adversely affect the performance of nuclear plant pressure transmitters; current testing interval of once in every fuel cycle is adequate for aging management; in-situ response time measurements and on-line calibration testing methods have been developed and validated for nuclear plant pressure transmitters; NUREG/CR-5851 should be taken into account for details of aging research on pressure transmitters

  11. Presentations provided

    Energy Technology Data Exchange (ETDEWEB)

    Hashemian, H; Beverly, D [Analysis and Measurement Services Corp., Knoxville, TN (United States)

    1999-12-31

    The following topics covered in detail at the workshop included: temperature instrumentation; pressure instrumentation; in-situ calibration and response time testing of RTDs and pressure transmitters; on-line performance monitoring and preventive maintenance of critical equipment; automated measurement of critical parameters; nuclear power plant infrastructure, management and Quality Assurance issues and recent developments for WWER and RBMK reactors. Conclusions drawn were: aging can adversely affect the performance of nuclear plant pressure transmitters; current testing interval of once in every fuel cycle is adequate for aging management; in-situ response time measurements and on-line calibration testing methods have been developed and validated for nuclear plant pressure transmitters; NUREG/CR-5851 should be taken into account for details of aging research on pressure transmitters

  12. Evaluation of poison information services provided by a new poison information center.

    Science.gov (United States)

    Churi, Shobha; Abraham, Lovin; Ramesh, M; Narahari, M G

    2013-01-01

    The aim of this study is to assess the nature and quality of services provided by poison information center established at a tertiary-care teaching hospital, Mysore. This was a prospective observational study. The poison information center was officially established in September 2010 and began its functioning thereafter. The center is equipped with required resources and facility (e.g., text books, Poisindex, Drugdex, toll free telephone service, internet and online services) to provide poison information services. The poison information services provided by the center were recorded in documentation forms. The documentation form consists of numerous sections to collect information on: (a) Type of population (children, adult, elderly or pregnant) (b) poisoning agents (c) route of exposure (d) type of poisoning (intentional, accidental or environmental) (e) demographic details of patient (age, gender and bodyweight) (f) enquirer details (background, place of call and mode of request) (g) category and purpose of query and (h) details of provided service (information provided, mode of provision, time taken to provide information and references consulted). The nature and quality of poison information services provided was assessed using a quality assessment checklist developed in accordance with DSE/World Health Organization guidelines. Chi-Square test (χ(2)). A total of 419 queries were received by the center. A majority (n = 333; 79.5%) of the queries were asked by the doctors to provide optimal care (n = 400; 95.5%). Most of the queries were received during ward rounds (n = 201; 48.0%), followed by direct access (n = 147; 35.1%). The poison information services were predominantly provided through verbal communication (n = 352; 84.0%). Upon receipt of queries, the required service was provided immediately (n = 103; 24.6%) or within 10-20 min (n = 296; 70.6%). The queries were mainly related to intentional poisoning (n = 258; 64.5%), followed by accidental poisoning

  13. Consumer Airfare Report: Table 5 - Detailed Fare Information For Highest and Lowest Fare Markets Under 750 Miles

    Data.gov (United States)

    Department of Transportation — Provides detailed fare information for highest and lowest fare markets under 750 miles. For a more complete explanation, please read the introductory information at...

  14. Practical Approaches for Detecting Selection in Microbial Genomes.

    Science.gov (United States)

    Hedge, Jessica; Wilson, Daniel J

    2016-02-01

    Microbial genome evolution is shaped by a variety of selective pressures. Understanding how these processes occur can help to address important problems in microbiology by explaining observed differences in phenotypes, including virulence and resistance to antibiotics. Greater access to whole-genome sequencing provides microbiologists with the opportunity to perform large-scale analyses of selection in novel settings, such as within individual hosts. This tutorial aims to guide researchers through the fundamentals underpinning popular methods for measuring selection in pathogens. These methods are transferable to a wide variety of organisms, and the exercises provided are designed for researchers with any level of programming experience.

  15. Active solar distillation - A detailed review

    Energy Technology Data Exchange (ETDEWEB)

    Sampathkumar, K.; Pitchandi, P. [Department of Mechanical Engineering, Tamilnadu College of Engineering, Coimbatore 641659, Tamilnadu (India); Arjunan, T.V. [Department of Automobile Engineering, PSG College of Technology, Coimbatore 641004, Tamilnadu (India); Senthilkumar, P. [Department of Mechanical Engineering, KSR College of Engineering, Tiruchengode 637215, Tamilnadu (India)

    2010-08-15

    All over the world, access to potable water to the people are narrowing down day by day. Most of the human diseases are due to polluted or non-purified water resources. Even today, under developed countries and developing countries face a huge water scarcity because of unplanned mechanism and pollution created by manmade activities. Water purification without affecting the ecosystem is the need of the hour. In this context, many conventional and non-conventional techniques have been developed for purification of saline water. Among these, solar distillation proves to be both economical and eco-friendly technique particularly in rural areas. Many active distillation systems have been developed to overcome the problem of lower distillate output in passive solar stills. This article provides a detailed review of different studies on active solar distillation system over the years. Thermal modelling was done for various types of active single slope solar distillation system. This review would also throw light on the scope for further research and recommendations in active solar distillation system. (author)

  16. Healthcare quality management in Switzerland--a survey among providers.

    Science.gov (United States)

    Kaderli, Reto; Pfortmueller, Carmen A; Businger, Adrian P

    2012-04-27

    In the last decade assessing the quality of healthcare has become increasingly important across the world. Switzerland lacks a detailed overview of how quality management is implemented and of its effects on medical procedures and patients' concerns. This study aimed to examine the systematics of quality management in Switzerland by assessing the providers and collected parameters of current quality initiatives. In summer 2011 we contacted all of the medical societies in Switzerland, the Federal Office of Public Health, the Swiss Medical Association (FMH) and the head of Swiss medical insurance providers, to obtain detailed information on current quality initiatives. All quality initiatives featuring standardised parameter assessment were included. Of the current 45 initiatives, 19 were powered by medical societies, five by hospitals, 11 by non-medical societies, two by the government, two by insurance companies or related institutions and six by unspecified institutions. In all, 24 medical registers, five seals of quality, five circles of quality, two self-assessment tools, seven superior entities, one checklist and one combined project existed. The cost of treatment was evaluated by four initiatives. A data report was released by 24 quality initiatives. The wide variety and the large number of 45 recorded quality initiatives provides a promising basis for effective healthcare quality management in Switzerland. However, an independent national supervisory authority should be appointed to provide an effective review of all quality initiatives and their transparency and coordination.

  17. Nuclear Weak Rates and Detailed Balance in Stellar Conditions

    Energy Technology Data Exchange (ETDEWEB)

    Misch, G. Wendell, E-mail: wendell@sjtu.edu, E-mail: wendell.misch@gmail.com [Department of Physics and Astronomy, Shanghai Jiao Tong University, 800 Dong Chuan Road, Shanghai 200240 (China)

    2017-07-20

    Detailed balance is often invoked in discussions of nuclear weak transitions in astrophysical environments. Satisfaction of detailed balance is rightly touted as a virtue of some methods of computing nuclear transition strengths, but I argue that it need not necessarily be strictly obeyed in astrophysical environments, especially when the environment is far from weak equilibrium. I present the results of shell model calculations of nuclear weak strengths in both charged-current and neutral-current channels at astrophysical temperatures, finding some violation of detailed balance. I show that a slight modification of the technique to strictly obey detailed balance has little effect on the reaction rates associated with these strengths under most conditions, though at high temperature the modified technique in fact misses some important strength. I comment on the relationship between detailed balance and weak equilibrium in astrophysical conditions.

  18. Neuroinflammation: the devil is in the details.

    Science.gov (United States)

    DiSabato, Damon J; Quan, Ning; Godbout, Jonathan P

    2016-10-01

    There is significant interest in understanding inflammatory responses within the brain and spinal cord. Inflammatory responses that are centralized within the brain and spinal cord are generally referred to as 'neuroinflammatory'. Aspects of neuroinflammation vary within the context of disease, injury, infection, or stress. The context, course, and duration of these inflammatory responses are all critical aspects in the understanding of these processes and their corresponding physiological, biochemical, and behavioral consequences. Microglia, innate immune cells of the CNS, play key roles in mediating these neuroinflammatory responses. Because the connotation of neuroinflammation is inherently negative and maladaptive, the majority of research focus is on the pathological aspects of neuroinflammation. There are, however, several degrees of neuroinflammatory responses, some of which are positive. In many circumstances including CNS injury, there is a balance of inflammatory and intrinsic repair processes that influences functional recovery. In addition, there are several other examples where communication between the brain and immune system involves neuroinflammatory processes that are beneficial and adaptive. The purpose of this review is to distinguish different variations of neuroinflammation in a context-specific manner and detail both positive and negative aspects of neuroinflammatory processes. In this review, we will use brain and spinal cord injury, stress, aging, and other inflammatory events to illustrate the potential harm and benefits inherent to neuroinflammation. Context, course, and duration of the inflammation are highly important to the interpretation of these events, and we aim to provide insight into this by detailing several commonly studied insults. This article is part of the 60th anniversary supplemental issue. © 2016 International Society for Neurochemistry.

  19. A Detailed Study of Rocky Planetary Material in the Hyades

    Science.gov (United States)

    Farihi, Jay

    2017-08-01

    The Hyades is the nearest open cluster, relatively young, and containing numerous A-type stars. Its youth, distance, and metallicity make it an ideal site to study planet formation around 2-3 Msun stars, and in a dynamically challenging environment.During our HST COS Snapshot, we discovered the ongoing accretion of Si-rich and C-deficient material in two white dwarf Hyads. The lower limit Si/C ratios determined from these 400s exposures indicate the material is more C-depleted than in chondritic meteorites, the most primitive rocks in the Solar System. Our 2013 Keck discovery of metal pollution in a third Hyades white dwarf indicates that planet formation is common in the cluster. Together, these three stars indicate that substantial minor bodies persist at several AU or more, and provide an unprecedented opportunity for a detailed study of rocky exoplanet precursors in a cluster environment.We propose to obtain detailed abundances of the planetary debris at these three polluted Hyads, which requires a modest investment of observatory time. The mass ratios between C, O, Mg, and Si are accurate indicators of the temperature and orbital regions where the parent bodies formed, their water and volatile contents. We will also detect Al and Fe, which are key indicators of differentiation and giant impacts among planetary embryos.Our proposed observations will provide legacy value for planet formation models, and especially those in cluster enviroments. These observations cannot be done from the ground or at optical or longer wavelengths, and must be carried out by HST in the ultraviolet.

  20. Detailed balance and reciprocity in solar cells

    Energy Technology Data Exchange (ETDEWEB)

    Kirchartz, Thomas; Rau, Uwe [IEF5-Photovoltaik, Forschungszentrum Juelich, 52425 Juelich (Germany)

    2008-12-15

    The limiting efficiency of photovoltaic devices follows from the detailed balance of absorption and emission of a diode according to the Shockley-Queisser theory. However, the principle of detailed balance has more implications for the understanding of photovoltaic devices than only defining the efficiency limit. We show how reciprocity relations between carrier collection and dark carrier injection, between electroluminescence emission and photovoltaic quantum efficiency and between open circuit voltage and light emitting diode quantum efficiency all follow from the principle of detailed balance. We also discuss the validity range of the Shockley-Queisser limit and the reciprocity relations. Discussing the validity of the reciprocity relations helps to deepen the understanding of photovoltaic devices and allows us to identify interrelationships between the superposition principle, the diode ideality and the reciprocity relations. (copyright 2008 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)

  1. 42 CFR 401.118 - Deletion of identifying details.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false Deletion of identifying details. 401.118 Section 401.118 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN... Deletion of identifying details. When CMS publishes or otherwise makes available an opinion or order...

  2. Can quantum coherent solar cells break detailed balance?

    International Nuclear Information System (INIS)

    Kirk, Alexander P.

    2015-01-01

    Carefully engineered coherent quantum states have been proposed as a design attribute that is hypothesized to enable solar photovoltaic cells to break the detailed balance (or radiative) limit of power conversion efficiency by possibly causing radiative recombination to be suppressed. However, in full compliance with the principles of statistical mechanics and the laws of thermodynamics, specially prepared coherent quantum states do not allow a solar photovoltaic cell—a quantum threshold energy conversion device—to exceed the detailed balance limit of power conversion efficiency. At the condition given by steady-state open circuit operation with zero nonradiative recombination, the photon absorption rate (or carrier photogeneration rate) must balance the photon emission rate (or carrier radiative recombination rate) thus ensuring that detailed balance prevails. Quantum state transitions, entropy-generating hot carrier relaxation, and photon absorption and emission rate balancing are employed holistically and self-consistently along with calculations of current density, voltage, and power conversion efficiency to explain why detailed balance may not be violated in solar photovoltaic cells

  3. Derivation of Markov processes that violate detailed balance

    Science.gov (United States)

    Lee, Julian

    2018-03-01

    Time-reversal symmetry of the microscopic laws dictates that the equilibrium distribution of a stochastic process must obey the condition of detailed balance. However, cyclic Markov processes that do not admit equilibrium distributions with detailed balance are often used to model systems driven out of equilibrium by external agents. I show that for a Markov model without detailed balance, an extended Markov model can be constructed, which explicitly includes the degrees of freedom for the driving agent and satisfies the detailed balance condition. The original cyclic Markov model for the driven system is then recovered as an approximation at early times by summing over the degrees of freedom for the driving agent. I also show that the widely accepted expression for the entropy production in a cyclic Markov model is actually a time derivative of an entropy component in the extended model. Further, I present an analytic expression for the entropy component that is hidden in the cyclic Markov model.

  4. Understanding ensemble protein folding at atomic detail

    International Nuclear Information System (INIS)

    Wallin, Stefan; Shakhnovich, Eugene I

    2008-01-01

    Although far from routine, simulating the folding of specific short protein chains on the computer, at a detailed atomic level, is starting to become a reality. This remarkable progress, which has been made over the last decade or so, allows a fundamental aspect of the protein folding process to be addressed, namely its statistical nature. In order to make quantitative comparisons with experimental kinetic data a complete ensemble view of folding must be achieved, with key observables averaged over the large number of microscopically different folding trajectories available to a protein chain. Here we review recent advances in atomic-level protein folding simulations and the new insight provided by them into the protein folding process. An important element in understanding ensemble folding kinetics are methods for analyzing many separate folding trajectories, and we discuss techniques developed to condense the large amount of information contained in an ensemble of trajectories into a manageable picture of the folding process. (topical review)

  5. Factors influencing detail detectability in radiologic imaging

    International Nuclear Information System (INIS)

    Gurvich, A.M.

    1985-01-01

    The detectability of various details is estimated quantitatively from the essential technical parameters of the imaging system and additional influencing factors including viewing of the image. The analysis implies the formation of the input radiation distribution (contrast formation, influence of kVp). Noise, image contrast (gamma), modulation transfer function and contrast threshold of the observer are of different influence on details of different size. Thus further optimization of imaging systems and their adaption to specific imaging tasks are facilitated

  6. Contribution to a Theory of Detailed Design

    DEFF Research Database (Denmark)

    Mortensen, Niels Henrik

    1999-01-01

    It has been recognised, that literature actually do not propose a theory of detailed design. In this paper a theory contribution is proposed, linking part design to organ design and allowing a type of functional reasoning. The proposed theory satisfies our need for explaining the nature of a part...... structure, for support of synthesis of part structure, i.e. detailed design, and our need for digital modelling of part structures.The aim of this paper is to contribute to a design theory valid for detailed design. The proposal is based upon the theory's ability to explain the nature of machine parts...... and assemblies, to support the synthesis of parts and to allow the modelling, especially digital modelling of a part structure. The contribution is based upon Theory of Technical Systems, Hubka, and the Domain Theory, Andreasen. This paper is based on a paper presented at ICED 99, Mortensen, but focus...

  7. 49 CFR 7.6 - Deletion of identifying detail.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false Deletion of identifying detail. 7.6 Section 7.6... To Be Made Public by DOT § 7.6 Deletion of identifying detail. Whenever it is determined to be... the deletion will accompany the record published or made available for inspection. ...

  8. Recent advances in biochemical and molecular diagnostics for the rapid detection of antibiotic-resistant Enterobacteriaceae: a focus on ß-lactam resistance.

    Science.gov (United States)

    Decousser, Jean-Winoc; Poirel, Laurent; Nordmann, Patrice

    2017-04-01

    The rapid detection of resistance is a challenge for clinical microbiologists who wish to prevent deleterious individual and collective consequences such as (i) delaying efficient antibiotic therapy, which worsens the survival rate of the most severely ill patients, or (ii) delaying the isolation of the carriers of multidrug-resistant bacteria and promoting outbreaks; this last consequence is of special concern, and there are an increasing number of approaches and market-based solutions in response. Areas covered: From simple, cheap biochemical tests to whole-genome sequencing, clinical microbiologists must select the most adequate phenotypic and genotypic tools to promptly detect and confirm β-lactam resistance from cultivated bacteria or from clinical specimens. Here, the authors review the published literature from the last 5 years about the primary technical approaches and commercial laboratory reagents for these purposes, including molecular, biochemical and immune assays. Furthermore, the authors discuss their intrinsic and relative performance, and we challenge their putative clinical impact. Expert commentary: Until the availability of fully automated wet and dry whole genome sequencing solutions, microbiologists should focus on inexpensive biochemical tests for cultured isolates or monomicrobial clinical specimen and on using the expensive molecular PCR-based strategies for the targeted screening of complex biological environments.

  9. Expanding the Availability of Lightweight Aluminum Alloy Armor Plate Procured from Detailed Military Specifications

    Science.gov (United States)

    Doherty, Kevin; Squillacioti, Richard; Cheeseman, Bryan; Placzankis, Brian; Gallardy, Denver

    For many years, the range of aluminum alloys for armor plate applications obtainable in accordance with detailed military specifications was very limited. However, the development of improved aluminum alloys for aerospace and other applications has provided an opportunity to modernize the Army portfolio for ground vehicle armor applications. While the benefits of offering additional alloy choices to vehicle designers is obvious, the process of creating detailed military specifications for armor plate applications is not trivial. A significant amount of material and testing is required to develop the details required by an armor plate specification. Due to the vast number of material programs that require standardization and with a limited amount of manpower and funds as a result of Standardization Reform in 1995, one typically requires a need statement from a vehicle program office to justify and sponsor the work. This presentation will focus on recent aluminum alloy armor plate specifications that have added capability to vehicle designers' selection of armor materials that offer possible benefits such as lower cost, higher strength, better ballistic and corrosion resistance, improved weldability, etc.

  10. Details and justifications for the MAP concept specification for acceleration above 63 GeV

    Energy Technology Data Exchange (ETDEWEB)

    Berg, J. Scott [Brookhaven National Lab. (BNL), Upton, NY (United States). Collider-Accelerator Dept.

    2014-02-28

    The Muon Accelerator Program (MAP) requires a concept specification for each of the accelerator systems. The Muon accelerators will bring the beam energy from a total energy of 63 GeV to the maximum energy that will fit on the Fermilab site. Justifications and supporting references are included, providing more detail than will appear in the concept specification itself.

  11. Preference for Well-Balanced Saliency in Details Cropped from Photographs

    Science.gov (United States)

    Abeln, Jonas; Fresz, Leonie; Amirshahi, Seyed Ali; McManus, I. Chris; Koch, Michael; Kreysa, Helene; Redies, Christoph

    2016-01-01

    Photographic cropping is the act of selecting part of a photograph to enhance its aesthetic appearance or visual impact. It is common practice with both professional (expert) and amateur (non-expert) photographers. In a psychometric study, McManus et al. (2011b) showed that participants cropped photographs confidently and reliably. Experts tended to select details from a wider range of positions than non-experts, but other croppers did not generally prefer details that were selected by experts. It remained unclear, however, on what grounds participants selected particular details from a photograph while avoiding other details. One of the factors contributing to cropping decision may be visual saliency. Indeed, various saliency-based computer algorithms are available for the automatic cropping of photographs. However, careful experimental studies on the relation between saliency and cropping are lacking to date. In the present study, we re-analyzed the data from the studies by McManus et al. (2011a,b), focusing on statistical image properties. We calculated saliency-based measures for details selected and details avoided during cropping. As expected, we found that selected details contain regions of higher saliency than avoided details on average. Moreover, the saliency center-of-mass was closer to the geometrical center in selected details than in avoided details. Results were confirmed in an eye tracking study with the same dataset of images. Interestingly, the observed regularities in cropping behavior were less pronounced for experts than for non-experts. In summary, our results suggest that, during cropping, participants tend to select salient regions and place them in an image composition that is well-balanced with respect to the distribution of saliency. Our study contributes to the knowledge of perceptual bottom-up features that are germane to aesthetic decisions in photography and their variability in non-experts and experts. PMID:26793086

  12. Detailed Balance Limit of Efficiency of Broadband-Pumped Lasers.

    Science.gov (United States)

    Nechayev, Sergey; Rotschild, Carmel

    2017-09-13

    Broadband light sources are a wide class of pumping schemes for lasers including LEDs, sunlight and flash lamps. Recently, efficient coupling of broadband light to high-quality micro-cavities has been demonstrated for on-chip applications and low-threshold solar-pumped lasers via cascade energy transfer. However, the conversion of incoherent to coherent light comes with an inherent price of reduced efficiency, which has yet to be assessed. In this paper, we derive the detailed balance limit of efficiency of broadband-pumped lasers and discuss how it is affected by the need to maintain a threshold population inversion and thermodynamically dictated minimal Stokes' shift. We show that lasers' slope efficiency is analogous to the nominal efficiency of solar cells, limited by thermalisation losses and additional unavoidable Stokes' shift. The lasers' power efficiency is analogous to the detailed balance limit of efficiency of solar cells, affected by the cavity mirrors and impedance matching factor, respectively. As an example we analyze the specific case of solar-pumped sensitized Nd 3+ :YAG-like lasers and define the conditions to reach their thermodynamic limit of efficiency. Our work establishes an upper theoretical limit for the efficiency of broadband-pumped lasers. Our general, yet flexible model also provides a way to incorporate other optical and thermodynamic losses and, hence, to estimate the efficiency of non-ideal broadband-pumped lasers.

  13. A detailed spectroscopic study of an Italian fresco

    International Nuclear Information System (INIS)

    Barilaro, Donatella; Crupi, Vincenza; Majolino, Domenico; Barone, Germana; Ponterio, Rosina

    2005-01-01

    In the present work we characterized samples of plasters and pictorial layers taken from a fresco in the Acireale Cathedral. The fresco represents the Coronation of Saint Venera, patron saint of this Ionian town. By performing a detailed spectroscopic analysis of the plaster preparation layer by Fourier-transform infrared (FTIR) spectroscopy and x-ray diffraction (XRD), and of the painting layer by FTIR and confocal Raman microspectroscopy, scanning electron microscopy+energy dispersive x-ray spectroscopy, and XRD, we were able to identify the pigments and the binders present. In particular, Raman investigation was crucial to the characterization of the pigments thanks to the high resolution of the confocal apparatus used. It is worth stressing that the simultaneous use of complementary techniques was able to provide more complete information for the conservation of the artifact we studied

  14. Temperature Measurements of Dense Plasmas by Detailed Balance

    International Nuclear Information System (INIS)

    Holl, A; Redmer, R; Ropke, G; Reinholz, H; Thiele, R; Fortmann, C; Forster, E; Cao, L; Tschentscher, T; Toleikis, S; Glenzer, S H

    2006-01-01

    Plasmas at high electron densities of n e = 10 20 - 10 26 cm -3 and moderate temperatures T e = 1 - 20 eV are important for laboratory astrophysics, high energy density science and inertial confinement fusion. These plasmas are usually referred to as Warm Dense Matter (WDM) and are characterized by a coupling parameter of Λ ∼> 1 where correlations become important. The characterization of such plasmas is still a challenging task due to the lack of direct measurement techniques for temperatures and densities. They propose to measure the Thomson scattering spectrum of vacuum-UV radiation off density fluctuations in the plasma. Collective Thomson scattering provides accurate data for the electron temperature applying first principles. Further, this method takes advantage of the spectral asymmetry resulting from detailed balance and is independent of collisional effects in these dense systems

  15. Detail Enhancement for Infrared Images Based on Propagated Image Filter

    Directory of Open Access Journals (Sweden)

    Yishu Peng

    2016-01-01

    Full Text Available For displaying high-dynamic-range images acquired by thermal camera systems, 14-bit raw infrared data should map into 8-bit gray values. This paper presents a new method for detail enhancement of infrared images to display the image with a relatively satisfied contrast and brightness, rich detail information, and no artifacts caused by the image processing. We first adopt a propagated image filter to smooth the input image and separate the image into the base layer and the detail layer. Then, we refine the base layer by using modified histogram projection for compressing. Meanwhile, the adaptive weights derived from the layer decomposition processing are used as the strict gain control for the detail layer. The final display result is obtained by recombining the two modified layers. Experimental results on both cooled and uncooled infrared data verify that the proposed method outperforms the method based on log-power histogram modification and bilateral filter-based detail enhancement in both detail enhancement and visual effect.

  16. Detailed measurements of structure functions from nucleons and nuclei

    CERN Multimedia

    2002-01-01

    The experiment will study deep inelastic muon nucleon scattering in a wide range of $Q^{2}$(1-200 (GeV/c)$^{2}$) and $x(0.005-0.75)$. The main aims of the experiment are: \\\\\\\\ a) Detailed measurements of the nuclear dependence of the structure function $F_{2}^{A}$, of $R = \\sigma_/\\sigma_{T}$ and of the cross-section for $J/\\psi$ production. They will provide a basis for the understanding of the EMC effect: the modification of quark and gluon distributions due to the nuclear environment. \\\\b) A simultaneous high luminosity measurement of the structure function $F_{2}$ on hydrogen and deuterium. This will provide substantially improved accuracy in the knowledge of the neutron structure function $F_{2}^{n}$, of $F_{2}^{p}-F_{2}^{n}$ and $F_{2}^{n}/F_{2}^{p}$ and their $Q^{2}$ dependence. Furthermore, the data will allow a determination of the strong coupling constant $\\alpha_{S}(Q^{2})$ with reduced experimental and theoretical uncertainties as well as of the ratio of the down to up quark distributions in the v...

  17. Detailed observations of the source of terrestrial narrowband electromagnetic radiation

    Science.gov (United States)

    Kurth, W. S.

    1982-01-01

    Detailed observations are presented of a region near the terrestrial plasmapause where narrowband electromagnetic radiation (previously called escaping nonthermal continuum radiation) is being generated. These observations show a direct correspondence between the narrowband radio emissions and electron cyclotron harmonic waves near the upper hybrid resonance frequency. In addition, electromagnetic radiation propagating in the Z-mode is observed in the source region which provides an extremely accurate determination of the electron plasma frequency and, hence, density profile of the source region. The data strongly suggest that electrostatic waves and not Cerenkov radiation are the source of the banded radio emissions and define the coupling which must be described by any viable theory.

  18. Doris A. Betancourt, Ph.D.

    Science.gov (United States)

    Request an environmental microbiologist. Her current research deals with screening indoor biocontaminutesants. She is responsible for the identification and characterization of mold, bacteria, and their metabolites in indoor environments.

  19. Post Entitlement Management Information - Detail Database

    Data.gov (United States)

    Social Security Administration — Contains data that supports the detailed and aggregate receipt, pending and clearance data, as well as other strategic and tactical MI for many Title II and Title...

  20. End region detailing of pretensioned concrete bridge girders : [summary].

    Science.gov (United States)

    2013-03-01

    Introduction of the Florida-I Beam (FIB) in 2009 renewed interest in prestressed concrete beam design, especially end region details. In this study, University of Florida researchers examined construction detailing at the FIB end region.

  1. A Content Analysis of Officer Perceptions of Detailing.

    Science.gov (United States)

    1981-03-01

    answer was "No Way"! Told me needs of service were in Philippine Island CNSG WESTPAC as OPS, three year tour. I wrote letter saying O.K. Was detailed as...off to them as it has to be least preferred of all tasks...personnel detailer. 2 I regret the tardiness of this reply - New Zealand is a long way

  2. The smallest cells pose the biggest problems: high-performance computing and the analysis of metagenome sequence data

    International Nuclear Information System (INIS)

    Edwards, R A

    2008-01-01

    New high-throughput DNA sequencing technologies have revolutionized how scientists study the organisms around us. In particular, microbiology - the study of the smallest, unseen organisms that pervade our lives - has embraced these new techniques to characterize and analyze the cellular constituents and use this information to develop novel tools, techniques, and therapeutics. So-called next-generation DNA sequencing platforms have resulted in huge increases in the amount of raw data that can be rapidly generated. Argonne National Laboratory developed the premier platform for the analysis of this new data (mg-rast) that is used by microbiologists worldwide. This paper uses the accounting from the computational analysis of more than 10,000,000,000 bp of DNA sequence data, describes an analysis of the advanced computational requirements, and suggests the level of analysis that will be essential as microbiologists move to understand how these tiny organisms affect our every day lives. The results from this analysis indicate that data analysis is a linear problem, but that most analyses are held up in queues. With sufficient resources, computations could be completed in a few hours for a typical dataset. These data also suggest execution times that delimit timely completion of computational analyses, and provide bounds for problematic processes

  3. Supercapacitor to Provide Ancillary Services: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Muljadi, Eduard [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Gevorgian, Vahan [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Luo, Yusheng [Idaho National Laboratory; Mohanpurkar, M. [Idaho National Laboratory; Hovsapian, R. [Idaho National Laboratory; Koritarov, V. [Argonne National Laboratory

    2017-10-09

    Supercapacitor technology has reached a level of maturity as a viable energy storage option available to support a modern electric power system grid; however, its application is still limited because of its energy capacity and the cost of the commercial product. In this paper, we demonstrate transient models of supercapacitor energy storage plants operating in coordination with run-of-the-river (ROR), doubly-fed induction generator hydropower plants (HPP) using a system control concept and architecture developed. A detailed transient model of a supercapacitor energy storage device is coupled with the grid via a three-phase inverter/rectifier and bidirectional DC-DC converter. In addition, we use a version of a 14-bus IEEE test case that includes the models of the supercapacitor energy storage device, ROR HPPs, and synchronous condensers that use the rotating synchronous generators of retired coal-powered plants. The purpose of the synchronous condensers is to enhance the system stability by providing voltage and reactive power control, provide power system oscillations damping, and maintain system inertia at secure levels. The control layer provides coordinated, decentralized operation of distributed ROR HPPs and energy storage as aggregate support to power system operations.

  4. Kaptive Web: User-Friendly Capsule and Lipopolysaccharide Serotype Prediction for Klebsiella Genomes.

    Science.gov (United States)

    Wick, Ryan R; Heinz, Eva; Holt, Kathryn E; Wyres, Kelly L

    2018-06-01

    As whole-genome sequencing becomes an established component of the microbiologist's toolbox, it is imperative that researchers, clinical microbiologists, and public health professionals have access to genomic analysis tools for the rapid extraction of epidemiologically and clinically relevant information. For the Gram-negative hospital pathogens such as Klebsiella pneumoniae , initial efforts have focused on the detection and surveillance of antimicrobial resistance genes and clones. However, with the resurgence of interest in alternative infection control strategies targeting Klebsiella surface polysaccharides, the ability to extract information about these antigens is increasingly important. Here we present Kaptive Web, an online tool for the rapid typing of Klebsiella K and O loci, which encode the polysaccharide capsule and lipopolysaccharide O antigen, respectively. Kaptive Web enables users to upload and analyze genome assemblies in a web browser. The results can be downloaded in tabular format or explored in detail via the graphical interface, making it accessible for users at all levels of computational expertise. We demonstrate Kaptive Web's utility by analyzing >500 K. pneumoniae genomes. We identify extensive K and O locus diversity among 201 genomes belonging to the carbapenemase-associated clonal group 258 (25 K and 6 O loci). The characterization of a further 309 genomes indicated that such diversity is common among the multidrug-resistant clones and that these loci represent useful epidemiological markers for strain subtyping. These findings reinforce the need for rapid, reliable, and accessible typing methods such as Kaptive Web. Kaptive Web is available for use at http://kaptive.holtlab.net/, and the source code is available at https://github.com/kelwyres/Kaptive-Web. Copyright © 2018 Wick et al.

  5. Practical Approaches for Detecting Selection in Microbial Genomes.

    Directory of Open Access Journals (Sweden)

    Jessica Hedge

    2016-02-01

    Full Text Available Microbial genome evolution is shaped by a variety of selective pressures. Understanding how these processes occur can help to address important problems in microbiology by explaining observed differences in phenotypes, including virulence and resistance to antibiotics. Greater access to whole-genome sequencing provides microbiologists with the opportunity to perform large-scale analyses of selection in novel settings, such as within individual hosts. This tutorial aims to guide researchers through the fundamentals underpinning popular methods for measuring selection in pathogens. These methods are transferable to a wide variety of organisms, and the exercises provided are designed for researchers with any level of programming experience.

  6. News in livestock research - use of Omics-technologies to study the microbiota in the gastrointestinal tract of farm animals.

    Science.gov (United States)

    Deusch, Simon; Tilocca, Bruno; Camarinha-Silva, Amélia; Seifert, Jana

    2015-01-01

    Technical progress in the field of next-generation sequencing, mass spectrometry and bioinformatics facilitates the study of highly complex biological samples such as taxonomic and functional characterization of microbial communities that virtually colonize all present ecological niches. Compared to the structural information obtained by metagenomic analyses, metaproteomic approaches provide, in addition, functional data about the investigated microbiota. In general, integration of the main Omics-technologies (genomics, transcriptomics, proteomics and metabolomics) in live science promises highly detailed information about the specific research object and helps to understand molecular changes in response to internal and external environmental factors. The microbial communities settled in the mammalian gastrointestinal tract are essential for the host metabolism and have a major impact on its physiology and health. The microbiotas of livestock like chicken, pig and ruminants are becoming a focus of interest for veterinaries, animal nutritionists and microbiologists. While pig is more often used as an animal model for human-related studies, the rumen microbiota harbors a diversity of enzymes converting complex carbohydrates into monomers which bears high potential for biotechnological applications. This review will provide a general overview about the recent Omics-based research of the microbiota in livestock including its major findings. Differences concerning the results of pre-Omics-approaches in livestock as well as the perspectives of this relatively new Omics-platform will be highlighted.

  7. Developments in remote sensing technology enable more detailed urban flood risk analysis.

    Science.gov (United States)

    Denniss, A.; Tewkesbury, A.

    2009-04-01

    Spaceborne remote sensors have been allowing us to build up a profile of planet earth for many years. With each new satellite launched we see the capabilities improve: new bands of data, higher resolution imagery, the ability to derive better elevation information. The combination of this geospatial data to create land cover and usage maps, all help inform catastrophe modelling systems. From Landsat 30m resolution to 2.44m QuickBird multispectral imagery; from 1m radar data collected by TerraSAR-X which enables rapid tracking of the rise and fall of a flood event, and will shortly have a twin satellite launched enabling elevation data creation; we are spoilt for choice in available data. However, just what is cost effective? It is always a question of choosing the appropriate level of input data detail for modelling, depending on the value of the risk. In the summer of 2007, the cost of the flooding in the UK was approximately £3bn and affected over 58,000 homes and businesses. When it comes to flood risk, we have traditionally considered rising river levels and surge tides, but with climate change and variations in our own construction behaviour, there are other factors to be taken into account. During those summer 2007 events, the Environment Agency suggested that around 70% of the properties damaged were the result of pluvial flooding, where high localised rainfall events overload localised drainage infrastructure, causing widespread flooding of properties and infrastructure. To create a risk model that is able to simulate such an event requires much more accurate source data than can be provided from satellite or radar. As these flood events cause considerable damage within relatively small, complex urban environments, therefore new high resolution remote sensing techniques have to be applied to better model these events. Detailed terrain data of England and Wales, plus cities in Scotland, have been produced by combining terrain measurements from the latest

  8. Statistical Analysis of Detailed 3-D CFD LES Simulations with Regard to CCV Modeling

    Directory of Open Access Journals (Sweden)

    Vítek Oldřich

    2016-06-01

    Full Text Available The paper deals with statistical analysis of large amount of detailed 3-D CFD data in terms of cycle-to-cycle variations (CCVs. These data were obtained by means of LES calculations of many consecutive cycles. Due to non-linear nature of Navier-Stokes equation set, there is a relatively significant CCV. Hence, every cycle is slightly different – this leads to requirement to perform statistical analysis based on ensemble averaging procedure which enables better understanding of CCV in ICE including its quantification. The data obtained from the averaging procedure provides results on different space resolution levels. The procedure is applied locally, i.e., in every cell of the mesh. Hence there is detailed CCV information on local level – such information can be compared with RANS simulations. Next, volume/mass averaging provides information at specific locations – e.g., gap between electrodes of a spark plug. Finally, volume/mass averaging of the whole combustion chamber leads to global information which can be compared with experimental data or results of system simulation tools (which are based on 0-D/1-D approach.

  9. DAGAL: Detailed Anatomy of Galaxies

    Science.gov (United States)

    Knapen, Johan H.

    2017-03-01

    The current IAU Symposium is closely connected to the EU-funded network DAGAL (Detailed Anatomy of Galaxies), with the final annual network meeting of DAGAL being at the core of this international symposium. In this short paper, we give an overview of DAGAL, its training activities, and some of the scientific advances that have been made under its umbrella.

  10. CMHC research project: Testing of air barrier construction details, II: Report

    Energy Technology Data Exchange (ETDEWEB)

    1993-01-01

    Air leakage control through the building envelope of wood framed houses is more important than ever. The leakage of air is controlled by the air barrier system. There are several new technologies to construct an air barrier system for the building envelope. These are the Poly Approach, the Air Drywall Approach and the EASE system. The development of these systems was undertaken primarily by the building community without significant research and development. The purpose of this study was to determine the actual performance of several different types of construction details for each of the different approaches. Each of these details was designed and constructed using one of the air barrier methods and tested in the laboratory. The test details included the sill plate, the partition wall, the stair stringer, the electrical outlets, the bathtub detail, the plumbing stack detail, the metal chimney detail, the bathroom fan detail and the EASE wall system.

  11. Applied Genomics of Foodborne Pathogens

    DEFF Research Database (Denmark)

    and customized source of information designed for and accessible to microbiologists interested in applying cutting-edge genomics in food safety and public health research. This book fills this void with a well-selected collection of topics, case studies, and bioinformatics tools contributed by experts......This book provides a timely and thorough snapshot into the emerging and fast evolving area of applied genomics of foodborne pathogens. Driven by the drastic advance of whole genome shot gun sequencing (WGS) technologies, genomics applications are becoming increasingly valuable and even essential...... at the forefront of foodborne pathogen genomics research....

  12. Severn Barrage project. Detailed report - V. 5

    Energy Technology Data Exchange (ETDEWEB)

    1989-01-01

    Prior to the present programme of work, the effects which a tidal power barrage would have on the region, during both construction and operation, had not been studied in detail. This volume of the Detailed Report therefore represents a significant extension of work into these aspects of the Severn Barrage Project. In the Regional Study, a number of benefits have been identified, some of which may represent net benefits nationally. The economic assessment of both regional and national benefits and costs is presented. The second part of this volume reports on the work done on the Legal Background for the Project. (author).

  13. Detailed Debunking of Denial

    Science.gov (United States)

    Enting, I. G.; Abraham, J. P.

    2012-12-01

    The disinformation campaign against climate science has been compared to a guerilla war whose tactics undermine the traditional checks and balances of science. One comprehensive approach has to been produce archives of generic responses such as the websites of RealClimate and SkepticalScience. We review our experiences with an alternative approach of detailed responses to a small number of high profile cases. Our particular examples were Professor Ian Plimer and Christopher Monckton, the Third Viscount Monckton of Brenchley, each of whom has been taken seriously by political leaders in our respective countries. We relate our experiences to comparable examples such as John Mashey's analysis of the Wegman report and the formal complaints about Lomborg's "Skeptical Environmentalist" and Durkin's "Great Global Warming Swindle". Our two approaches used contrasting approaches: an on-line video of a lecture vs an evolving compendium of misrepresentations. Additionally our approaches differed in the emphasis. The analysis of Monckton concentrated on the misrepresentation of the science, while the analysis of Plimer concentrated on departures from accepted scientific practice: fabrication of data, misrepresentation of cited sources and unattributed use of the work of others. Benefits of an evolving compendium were the ability to incorporate contributions from members of the public who had identified additional errors and the scope for addressing new aspects as they came to public attention. `Detailed debunking' gives non-specialists a reference point for distinguishing non-science when engaging in public debate.

  14. Detailed Characterization of Nearshore Processes During NCEX

    Science.gov (United States)

    Holland, K.; Kaihatu, J. M.; Plant, N.

    2004-12-01

    Recent technology advances have allowed the coupling of remote sensing methods with advanced wave and circulation models to yield detailed characterizations of nearshore processes. This methodology was demonstrated as part of the Nearshore Canyon EXperiment (NCEX) in La Jolla, CA during Fall 2003. An array of high-resolution, color digital cameras was installed to monitor an alongshore distance of nearly 2 km out to depths of 25 m. This digital imagery was analyzed over the three-month period through an automated process to produce hourly estimates of wave period, wave direction, breaker height, shoreline position, sandbar location, and bathymetry at numerous locations during daylight hours. Interesting wave propagation patterns in the vicinity of the canyons were observed. In addition, directional wave spectra and swash / surf flow velocities were estimated using more computationally intensive methods. These measurements were used to provide forcing and boundary conditions for the Delft3D wave and circulation model, giving additional estimates of nearshore processes such as dissipation and rip currents. An optimal approach for coupling these remotely sensed observations to the numerical model was selected to yield accurate, but also timely characterizations. This involved assimilation of directional spectral estimates near the offshore boundary to mimic forcing conditions achieved under traditional approaches involving nested domains. Measurements of breaker heights and flow speeds were also used to adaptively tune model parameters to provide enhanced accuracy. Comparisons of model predictions and video observations show significant correlation. As compared to nesting within larger-scale and coarser resolution models, the advantages of providing boundary conditions data using remote sensing is much improved resolution and fidelity. For example, rip current development was both modeled and observed. These results indicate that this approach to data-model coupling

  15. Visualizing Tensor Normal Distributions at Multiple Levels of Detail.

    Science.gov (United States)

    Abbasloo, Amin; Wiens, Vitalis; Hermann, Max; Schultz, Thomas

    2016-01-01

    Despite the widely recognized importance of symmetric second order tensor fields in medicine and engineering, the visualization of data uncertainty in tensor fields is still in its infancy. A recently proposed tensorial normal distribution, involving a fourth order covariance tensor, provides a mathematical description of how different aspects of the tensor field, such as trace, anisotropy, or orientation, vary and covary at each point. However, this wealth of information is far too rich for a human analyst to take in at a single glance, and no suitable visualization tools are available. We propose a novel approach that facilitates visual analysis of tensor covariance at multiple levels of detail. We start with a visual abstraction that uses slice views and direct volume rendering to indicate large-scale changes in the covariance structure, and locations with high overall variance. We then provide tools for interactive exploration, making it possible to drill down into different types of variability, such as in shape or orientation. Finally, we allow the analyst to focus on specific locations of the field, and provide tensor glyph animations and overlays that intuitively depict confidence intervals at those points. Our system is demonstrated by investigating the effects of measurement noise on diffusion tensor MRI, and by analyzing two ensembles of stress tensor fields from solid mechanics.

  16. Meet EPA researcher Dawn King

    Science.gov (United States)

    Research microbiologist Dawn King works in EPA’s National Exposure Research Laboratory where she identifies and assesses the health risk of microbial pathogens in water. This is her researchers at work profile.

  17. Detailed site characterization for final disposal of spent fuel in Finland - Case study Loviisa

    International Nuclear Information System (INIS)

    Anttila, P.; Ahokas, H.; Ruotsalainen, P.; Cosma, C.; Keskinen, J.; Hinkkanen, H.; Rouhiainen, P.; Oehberg, A.

    1998-01-01

    The spent fuel from the Finnish nuclear power plants will be disposed of in the Finnish bedrock. Pos iva Oy is responsible for the site selection programme carried out in accordance with the governmental decisions. Preliminary site investigations were made in five areas in 1987-1992. Based on the results, three areas, Romuvaara in Kuhmo, Kivetty in Aeaenekoski and Olkiluoto in Eurajoki, were selected for the detailed site characterization in 1993-2000. The final site will be selected by the end of the year 2000. The interim reporting of the detailed studies of the three areas was made in 1996. In 1997, the island of Haestholmen, as the host to the Loviisa NPP, was included as a fourth candidate site in the programme for the detailed site investigations. The goal is to characterize this site also in detail by the end of 2000 to attain the same level of knowledge as available from the three other sites. The background information existing from the studies made for the construction of the repository for the low-and intermediate-level wastes will create a good basis to reach the target. The research programme for the detailed site characterization has mainly been focused on groundwater flow and geochemistry due to their importance in terms of long-term safety of the repository. Equipment and methodology development by Posiva has introduced new tools that provide more accurate data on relevant parameters than the ones used in previous stages of site characterization. The programme also contains studies for additional information of the structural and geological properties of the bedrock towards the depth. Also predictive modelling has been made for evaluating the relevance of the assumptions made. The methods applied in the site characterization have comprised, e.g., geological mapping, deep core drilling, groundwater sampling and analyzing, hydraulic testing and geophysical measurements

  18. Detailed site characterization for final disposal of spent fuel in Finland - Case study Loviisa

    Energy Technology Data Exchange (ETDEWEB)

    Anttila, P. [IVO Power Engineering Ltd. (Finland); Ahokas, H.; Ruotsalainen, P. [Fintact Oy (Finland); Cosma, C.; Keskinen, J. [Vibrometric Oy (Finland); Hinkkanen, H. [Posiva Oy (Finland); Rouhiainen, P. [PRG-Tec Oy (Finland); Oehberg, A. [Saanio and Riekkola Consulting Engineers (Finland)

    1998-09-01

    The spent fuel from the Finnish nuclear power plants will be disposed of in the Finnish bedrock. Pos iva Oy is responsible for the site selection programme carried out in accordance with the governmental decisions. Preliminary site investigations were made in five areas in 1987-1992. Based on the results, three areas, Romuvaara in Kuhmo, Kivetty in Aeaenekoski and Olkiluoto in Eurajoki, were selected for the detailed site characterization in 1993-2000. The final site will be selected by the end of the year 2000. The interim reporting of the detailed studies of the three areas was made in 1996. In 1997, the island of Haestholmen, as the host to the Loviisa NPP, was included as a fourth candidate site in the programme for the detailed site investigations. The goal is to characterize this site also in detail by the end of 2000 to attain the same level of knowledge as available from the three other sites. The background information existing from the studies made for the construction of the repository for the low-and intermediate-level wastes will create a good basis to reach the target. The research programme for the detailed site characterization has mainly been focused on groundwater flow and geochemistry due to their importance in terms of long-term safety of the repository. Equipment and methodology development by Posiva has introduced new tools that provide more accurate data on relevant parameters than the ones used in previous stages of site characterization. The programme also contains studies for additional information of the structural and geological properties of the bedrock towards the depth. Also predictive modelling has been made for evaluating the relevance of the assumptions made. The methods applied in the site characterization have comprised, e.g., geological mapping, deep core drilling, groundwater sampling and analyzing, hydraulic testing and geophysical measurements 23 refs, 4 figs

  19. Detailed geologic modeling of a turbidity reservoir interval at the Mars discovery

    Energy Technology Data Exchange (ETDEWEB)

    Mahaffie, M.J.; Chapin, M.A. [Shell Exploration and Production Technology Co. (United States); Henry, W.A. [Shell Offshore, Inc. (United States)

    1995-12-31

    Detailed reservoir architecture studies using high resolution seismic data coupled with geologic and seismic inversion modeling have been used to evaluate a major hydrocarbon bearing turbidite reservoir found within Prospect Mars. Early interpretations of this interval, based on lower frequency (40 Hz) seismic data, indicated the presence of a single, laterally continuous event covering an area nearly 3 miles square ({approx} 5200 acres). Correlations from well control supported the notion that this seismic event comprised a series of continuous sheet sands exhibiting a high degree of lateral continuity and connectivity. However pressure data taken during fluid sampling of the reservoir suggested the possibility of discontinuities not observed within the resolution of the seismic data. Seismic reprocessing enhancements to increase frequency content revealed the presence of multiple stratigraphic features not previously recognized. Detailed seismic mapping using loop-level seismic attributes and seismic inversion studies constrained by geologic models provide a more realistic depiction of the environment of deposition and improve reservoir simulation modeling for this stratigraphic interval. (author). 3 figs

  20. Madagascar’s Mangroves: Quantifying Nation-Wide and Ecosystem Specific Dynamics, and Detailed Contemporary Mapping of Distinct Ecosystems

    Directory of Open Access Journals (Sweden)

    Trevor G. Jones

    2016-01-01

    Full Text Available Mangrove ecosystems help mitigate climate change, are highly biodiverse, and provide critical goods and services to coastal communities. Despite their importance, anthropogenic activities are rapidly degrading and deforesting mangroves world-wide. Madagascar contains 2% of the world’s mangroves, many of which have undergone or are starting to exhibit signs of widespread degradation and deforestation. Remotely sensed data can be used to quantify mangrove loss and characterize remaining distributions, providing detailed, accurate, timely and updateable information. We use USGS maps produced from Landsat data to calculate nation-wide dynamics for Madagascar’s mangroves from 1990 to 2010, and examine change more closely by partitioning the national distribution in to primary (i.e., >1000 ha ecosystems; with focus on four Areas of Interest (AOIs: Ambaro-Ambanja Bays (AAB, Mahajamba Bay (MHJ, Tsiribihina Manombolo Delta (TMD and Bay des Assassins (BdA. Results indicate a nation–wide net-loss of 21% (i.e., 57,359 ha from 1990 to 2010, with dynamics varying considerably among primary mangrove ecosystems. Given the limitations of national-level maps for certain localized applications (e.g., carbon stock inventories, building on two previous studies for AAB and MHJ, we employ Landsat data to produce detailed, contemporary mangrove maps for TMD and BdA. These contemporary, AOI-specific maps provide improved detail and accuracy over the USGS national-level maps, and are being applied to conservation and restoration initiatives through the Blue Ventures’ Blue Forests programme and WWF Madagascar West Indian Ocean Programme Office’s work in the region.

  1. Guide to dataflow supercomputing basic concepts, case studies, and a detailed example

    CERN Document Server

    Milutinovic, Veljko; Trifunovic, Nemanja; Giorgi, Roberto

    2015-01-01

    This unique text/reference describes an exciting and novel approach to supercomputing in the DataFlow paradigm. The major advantages and applications of this approach are clearly described, and a detailed explanation of the programming model is provided using simple yet effective examples. The work is developed from a series of lecture courses taught by the authors in more than 40 universities across more than 20 countries, and from research carried out by Maxeler Technologies, Inc. Topics and features: presents a thorough introduction to DataFlow supercomputing for big data problems; revie

  2. Salt Block I test: experimental details and comparison with theory. Final report

    International Nuclear Information System (INIS)

    Duffey, T.A.

    1980-02-01

    A series of laboratory experiments has been completed at Sandia Laboratories to provide an understanding of the steady state and transient thermal response of a large salt block containing an internal heat source. In this report, details of the experimental program are presented along with results of related efforts, such as thermal conductivity experiments, done in support of the heater experiments (Salt Block I). Finite element temperature field predictions, both transient and steady state, are performed utilizing the COYOTE nonlinear heat conduction program. Comparisons of experimental and theoretical results are generally quite good

  3. Detailed description of an SSAC at the facility level for research reactors

    International Nuclear Information System (INIS)

    Jones, R.J.

    1984-09-01

    The purpose of this document is to provide a detailed description of a system for the accounting for and control of nuclear material in a research reactor facility which can be used by a facility operator to establish his own system to comply with a national system for nuclear material accounting and control and to facilitate application of IAEA safeguards. The scope of this document is limited to descriptions of the following SSAC elements: (1) Nuclear Material Measurements; (2) Measurement Quality; (3) Records and Reports; (4) Physical Inventory Taking; (5) Material Balance Closing

  4. Preliminary evaluation of crisis-relocation fallout-shelter options. Volume 2. Detailed analysis

    International Nuclear Information System (INIS)

    Santini, D.J.; Clinch, J.M.; Davis, F.H.; Hill, L.G.; Lynch, E.P.; Tanzman, E.A.; Wernette, D.R.

    1982-12-01

    This report presents a preliminary, detailed evaluation of various shelter options for use if the President orders crisis relocation of the US urban population because of strong expectation of a nuclear war. The availability of livable shelter space at 40 ft 2 per person (congregate-care space) by state is evaluated. Options are evaluated for construction of fallout shelters allowing 10 ft 2 per person - such shelters are designed to provide 100% survival at projected levels of radioactive fallout. The FEMA concept of upgrading existing buildings to act as fallout shelters can, in principle, provide adequate shelter throughout most of the US. Exceptions are noted and remedies proposed. In terms of upgrading existing buildings to fallout shelter status, great benefits are possible by turning away from a standard national approach and adopting a more site-specific approach. Existing FEMA research provides a solid foundation for successful crisis relocation planning, but the program can be refined by making suitable modifications in its locational, engineering, and institutionally specific elements

  5. Airborne gamma-ray spectrometer and magnetometer survey, Durango C, Colorado. Final report Volume II A. Detail area

    International Nuclear Information System (INIS)

    1983-01-01

    Geology of Durango C detail area, radioactive mineral occurrences in Colorado, and geophysical data interpretation are included in this report. Eight appendices provide: stacked profiles, geologic histograms, geochemical histograms, speed and altitude histograms, geologic statistical tables, magnetic and ancillary profiles, and test line data

  6. Exploring new models in all detail with SARAH

    CERN Document Server

    Staub, Florian

    2015-01-01

    I give an overview about the features the Mathematica package SARAH provides to study new models. In general, SARAH can handle a wide range of models beyond the MSSM coming with additional chiral superfields, extra gauge groups, or distinctive features like Dirac gaugino masses. All of these models can be implemented in a compact form in SARAH and are easy to use: SARAH extracts all analytical properties of the given model like two-loop renormalization group equations, tadpole equations, mass matrices and vertices. Also one- and two-loop corrections to tadpoles and self-energies can be obtained. For numerical calculations SARAH can be interfaced to other tools to get the mass spectrum, to check flavour or dark matter constraints, and to test the vacuum stability, or to perform collider studies. In particular, the interface to SPheno allows a precise prediction of the Higgs mass in a given model comparable to MSSM precision by incorporating the important two-loop corrections. I show in great detail at the exam...

  7. A detailed gravimetric geoid from North America to Eurasia

    Science.gov (United States)

    Vincent, S. F.; Strange, W. E.; Marsh, J. G.

    1972-01-01

    A detailed gravimetric geoid of the United States, North Atlantic, and Eurasia, which was computed from a combination of satellite derived and surface gravity data, is presented. The precision of this detailed geoid is + or - 2 to + or - 3 m in the continents but may be in the range of 5 to 7 m in those areas where data is sparse. Comparisons of the detailed gravimetric geoid with results of Rapp, Fischer, and Rice for the United States, Bomford in Europe, and Heiskanen and Fischer in India are presented. Comparisons are also presented with geoid heights from satellite solutions for geocentric station coordinates in North America, the Caribbean, and Europe.

  8. Testing for detailed balance in a financial market

    Science.gov (United States)

    Fiebig, H. R.; Musgrove, D. P.

    2015-06-01

    We test a historical price-time series in a financial market (the NASDAQ 100 index) for a statistical property known as detailed balance. The presence of detailed balance would imply that the market can be modeled by a stochastic process based on a Markov chain, thus leading to equilibrium. In economic terms, a positive outcome of the test would support the efficient market hypothesis, a cornerstone of neo-classical economic theory. In contrast to the usage in prevalent economic theory the term equilibrium here is tied to the returns, rather than the price-time series. The test is based on an action functional S constructed from the elements of the detailed balance condition and the historical data set, and then analyzing S by means of simulated annealing. Checks are performed to verify the validity of the analysis method. We discuss the outcome of this analysis.

  9. Detailed sectional anatomy of the spine

    International Nuclear Information System (INIS)

    Rauschning, W.

    1985-01-01

    Morphologic studies on the human spine constitute a special challenge because of the spine's complex topographic anatomy and the intimate relationship between the supporting skeleton and the contiguous soft tissues (muscles, discs, joint capsules) as well as the neurovascular contents of the spinal canal and intervertebral foramina. The improving resolution and multiplanar image reformatting capabilities of modern CT scanners call for accurate anatomic reference material. Such anatomic images should be available without distortion, in natural colors, and in considerable detail. The images should present the anatomy in the correct axial, sagittal, and coronal planes and should also be sufficiently closely spaced so as to follow the thin cuts of modern CT scanners. This chapter details one of several recent attempts to correlate gross anatomy with the images depicted by high-resolution CT. The methods of specimen preparation, sectioning, and photographing have been documented elsewhere

  10. 5 CFR 370.107 - Details to small business concerns.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Details to small business concerns. 370... INFORMATION TECHNOLOGY EXCHANGE PROGRAM § 370.107 Details to small business concerns. (a) The head of each... organizations in each calendar year, at least 20 percent are to small business concerns, in accordance with 5 U...

  11. Detailed modeling of mountain wave PSCs

    Directory of Open Access Journals (Sweden)

    S. Fueglistaler

    2003-01-01

    Full Text Available Polar stratospheric clouds (PSCs play a key role in polar ozone depletion. In the Arctic, PSCs can occur on the mesoscale due to orographically induced gravity waves. Here we present a detailed study of a mountain wave PSC event on 25-27 January 2000 over Scandinavia. The mountain wave PSCs were intensively observed by in-situ and remote-sensing techniques during the second phase of the SOLVE/THESEO-2000 Arctic campaign. We use these excellent data of PSC observations on 3 successive days to analyze the PSCs and to perform a detailed comparison with modeled clouds. We simulated the 3-dimensional PSC structure on all 3 days with a mesoscale numerical weather prediction (NWP model and a microphysical box model (using best available nucleation rates for ice and nitric acid trihydrate particles. We show that the combined mesoscale/microphysical model is capable of reproducing the PSC measurements within the uncertainty of data interpretation with respect to spatial dimensions, temporal development and microphysical properties, without manipulating temperatures or using other tuning parameters. In contrast, microphysical modeling based upon coarser scale global NWP data, e.g. current ECMWF analysis data, cannot reproduce observations, in particular the occurrence of ice and nitric acid trihydrate clouds. Combined mesoscale/microphysical modeling may be used for detailed a posteriori PSC analysis and for future Arctic campaign flight and mission planning. The fact that remote sensing alone cannot further constrain model results due to uncertainities in the interpretation of measurements, underlines the need for synchronous in-situ PSC observations in campaigns.

  12. Spent fuel characteristics provided by the CDB: An update

    International Nuclear Information System (INIS)

    Notz, K.J.; Salmon, R.; Welch, T.D.; Reich, W.J.; Moore, R.S.

    1992-01-01

    The Characteristics Data Base (CDB) task provides OCRWM with the detailed technical characteristics of potential repository wastes, which consist primarily of commercial spent nuclear fuel, but also includes other spent fuel (and also high-level and miscellaneous wastes). A major revision of the original CDB report and PC data bases has just been completed under formal QA peer review guidelines and Revision 1 is ready to be issued. This paper describes the classification scheme developed for LWR fuel assemblies and the five PC data bases for LWR spent fuel, which provide data on quantities, assemblies, radiological properties, non-fuel assembly hardware, and serial numbers. The future role of other (i.e., non-LWR) spent fuel is also cited

  13. Airborne gamma-ray spectrometer and magnetometer survey, Durango D, Colorado. Final report Volume II A. Detail area

    International Nuclear Information System (INIS)

    1983-01-01

    This volume contains geology of the Durango D detail area, radioactive mineral occurrences in Colorado, and geophysical data interpretation. Eight appendices provide: stacked profiles, geologic histograms, geochemical histograms, speed and altitude histograms, geologic statistical tables, geochemical statistical tables, magnetic and ancillary profiles, and test line data

  14. Association Between Academic Medical Center Pharmaceutical Detailing Policies and Physician Prescribing.

    Science.gov (United States)

    Larkin, Ian; Ang, Desmond; Steinhart, Jonathan; Chao, Matthew; Patterson, Mark; Sah, Sunita; Wu, Tina; Schoenbaum, Michael; Hutchins, David; Brennan, Troyen; Loewenstein, George

    2017-05-02

    In an effort to regulate physician conflicts of interest, some US academic medical centers (AMCs) enacted policies restricting pharmaceutical representative sales visits to physicians (known as detailing) between 2006 and 2012. Little is known about the effect of these policies on physician prescribing. To analyze the association between detailing policies enacted at AMCs and physician prescribing of actively detailed and not detailed drugs. The study used a difference-in-differences multivariable regression analysis to compare changes in prescribing by physicians before and after implementation of detailing policies at AMCs in 5 states (California, Illinois, Massachusetts, Pennsylvania, and New York) that made up the intervention group with changes in prescribing by a matched control group of similar physicians not subject to a detailing policy. Academic medical center implementation of policies regulating pharmaceutical salesperson visits to attending physicians. The monthly within-drug class market share of prescriptions written by an individual physician for detailed and nondetailed drugs in 8 drug classes (lipid-lowering drugs, gastroesophageal reflux disease drugs, diabetes drugs, antihypertensive drugs, hypnotic drugs approved for the treatment of insomnia [sleep aids], attention-deficit/hyperactivity disorder drugs, antidepressant drugs, and antipsychotic drugs) comparing the 10- to 36-month period before implementation of the detailing policies with the 12- to 36-month period after implementation, depending on data availability. The analysis included 16 121 483 prescriptions written between January 2006 and June 2012 by 2126 attending physicians at the 19 intervention group AMCs and by 24 593 matched control group physicians. The sample mean market share at the physician-drug-month level for detailed and nondetailed drugs prior to enactment of policies was 19.3% and 14.2%, respectively. Exposure to an AMC detailing policy was associated with a

  15. GEOMETRIC MODELLING OF TREE ROOTS WITH DIFFERENT LEVELS OF DETAIL

    Directory of Open Access Journals (Sweden)

    J. I. Guerrero Iñiguez

    2017-09-01

    Full Text Available This paper presents a geometric approach for modelling tree roots with different Levels of Detail, suitable for analysis of the tree anchoring, potentially occupied underground space, interaction with urban elements and damage produced and taken in the built-in environment. Three types of tree roots are considered to cover several species: tap root, heart shaped root and lateral roots. Shrubs and smaller plants are not considered, however, a similar approach can be considered if the information is available for individual species. The geometrical approach considers the difficulties of modelling the actual roots, which are dynamic and almost opaque to direct observation, proposing generalized versions. For each type of root, different geometric models are considered to capture the overall shape of the root, a simplified block model, and a planar or surface projected version. Lower detail versions are considered as compatibility version for 2D systems while higher detail models are suitable for 3D analysis and visualization. The proposed levels of detail are matched with CityGML Levels of Detail, enabling both analysis and aesthetic views for urban modelling.

  16. Geometric Modelling of Tree Roots with Different Levels of Detail

    Science.gov (United States)

    Guerrero Iñiguez, J. I.

    2017-09-01

    This paper presents a geometric approach for modelling tree roots with different Levels of Detail, suitable for analysis of the tree anchoring, potentially occupied underground space, interaction with urban elements and damage produced and taken in the built-in environment. Three types of tree roots are considered to cover several species: tap root, heart shaped root and lateral roots. Shrubs and smaller plants are not considered, however, a similar approach can be considered if the information is available for individual species. The geometrical approach considers the difficulties of modelling the actual roots, which are dynamic and almost opaque to direct observation, proposing generalized versions. For each type of root, different geometric models are considered to capture the overall shape of the root, a simplified block model, and a planar or surface projected version. Lower detail versions are considered as compatibility version for 2D systems while higher detail models are suitable for 3D analysis and visualization. The proposed levels of detail are matched with CityGML Levels of Detail, enabling both analysis and aesthetic views for urban modelling.

  17. How do providers discuss the results of pediatric exome sequencing with families?

    Science.gov (United States)

    Walser, Sarah A; Werner-Lin, Allison; Mueller, Rebecca; Miller, Victoria A; Biswas, Sawona; Bernhardt, Barbara A

    2017-09-01

    This study provides preliminary data on the process and content of returning results from exome sequencing offered to children through one of the Clinical Sequencing Exploratory Research (CSER) projects. We recorded 25 sessions where providers returned diagnostic and secondary sequencing results to families. Data interpretation utilized inductive thematic analysis. Typically, providers followed a results report and discussed diagnostic findings using technical genomic and sequencing concepts. We identified four provider processes for returning results: teaching genetic concepts; assessing family response; personalizing findings; and strengthening patient-provider relationships. Sessions should reflect family interest in medical management and next steps, and minimize detailed genomic concepts. As the scope and complexity of sequencing increase, the traditional information-laden counseling model requires revision.

  18. Dynamical twisted mass fermions with light quarks. Simulation and analysis details

    Energy Technology Data Exchange (ETDEWEB)

    Boucaud, P. [Paris-11 Univ., 91 - Orsay (France). Lab. de Physique Theorique; Dimopoulos, P. [Rome-2 Univ. (Italy). Dipt. di Fisica; Farchioni, F. [Muenster Univ. (DE). Inst. fuer Theoretische Physik] (and others)

    2008-03-15

    In a recent paper (2007) we presented precise lattice QCD results of our European Twisted Mass Collaboration (ETMC). They were obtained by employing two mass-degenerate flavours of twisted mass fermions at maximal twist. In the present paper we give details on our simulations and the computation of physical observables. In particular, we discuss the problem of tuning to maximal twist, the techniques we have used to compute correlators and error estimates. In addition, we provide more information on the algorithm used, the autocorrelation times and scale determination, the evaluation of disconnected contributions and the description of our data by means of chiral perturbation theory formulae. (orig.)

  19. Dynamical twisted mass fermions with light quarks. Simulation and analysis details

    International Nuclear Information System (INIS)

    Boucaud, P.; Dimopoulos, P.; Farchioni, F.

    2008-03-01

    In a recent paper (2007) we presented precise lattice QCD results of our European Twisted Mass Collaboration (ETMC). They were obtained by employing two mass-degenerate flavours of twisted mass fermions at maximal twist. In the present paper we give details on our simulations and the computation of physical observables. In particular, we discuss the problem of tuning to maximal twist, the techniques we have used to compute correlators and error estimates. In addition, we provide more information on the algorithm used, the autocorrelation times and scale determination, the evaluation of disconnected contributions and the description of our data by means of chiral perturbation theory formulae. (orig.)

  20. Results of availability imposed configuration details developed for K-DEMO

    Energy Technology Data Exchange (ETDEWEB)

    Brown, Tom, E-mail: tbrown@pppl.gov [Princeton Plasma Physics Laboratory, Princeton, NJ 08543 (United States); Titus, Peter; Brooks, Art; Zhang, Han; Neilson, Hutch [Princeton Plasma Physics Laboratory, Princeton, NJ 08543 (United States); Im, Kihak; Kim, Keeman [National Fusion Research Institute, Daejeon 305-806 (Korea, Republic of)

    2016-11-01

    The Korean fusion demonstration reactor (K-DEMO) has completed a two year study looking at key Tokamak components and configuration options in preparation of a conceptual design phase. A key part of a device configuration centers on defining an arrangement that enhances the ability to reach high availability values by defining design solutions that foster simplified maintenance operations. To maximize the size and minimize the number of in-vessel components enlarged TF coils were defined that incorporate a pair of windings within each coil to mitigate pressure drop issues and to reduce the cost of the coils. A semi-permanent shield structure was defined to develop labyrinth interfaces between double-null plasma contoured shield modules, provide an entity to align blanket components and provide support against disruption loads—with a load path that equilibrates blanket, TF and PF loads through a base structure. Blanket piping services and auxiliary systems that interface with in-vessel components have played a major role in defining the overall device arrangement—concept details will be presented along with general arrangement features and preliminary results obtained from disruption analysis.

  1. Pharmaceutical drug detailing in primary care: extent and methods

    DEFF Research Database (Denmark)

    Schramm, Jesper

    The dimension and methods of pharmaceutical marketing towards 47 danish general practitioners is described. Conclusions: Pharmaceutical drug detailing possesses a huge potential to influence the prescription pattern of GP's.......The dimension and methods of pharmaceutical marketing towards 47 danish general practitioners is described. Conclusions: Pharmaceutical drug detailing possesses a huge potential to influence the prescription pattern of GP's....

  2. Bolivia-Brazil gas line route detailed

    International Nuclear Information System (INIS)

    Anon.

    1992-01-01

    This paper reports that state oil companies of Brazil and Bolivia have signed an agreement outlining the route for a 2,270 km pipeline system to deliver natural gas from Bolivian fields to Southeast Brazil. The two sides currently are negotiating details about construction costs as well as contract volumes and prices. Capacity is projected at 283-565 MMcfd. No official details are available, but Roberto Y. Hukai, a director of the Sao Paulo engineering company Jaako Poyry/Technoplan, estimates transportation cost of the Bolivian gas at 90 cents/MMBTU. That would be competitive with the price of gas delivered to the Sao Paulo gas utility Comgas, he the. Brazil's Petroleos Brasileiro SA estimates construction of the pipeline on the Brazilian side alone with cost $1.2-1.4 billion. Bolivia's Yacimientos Petroliferos Fiscales Bolivianos (YPFB) is negotiating with private domestic and foreign investors for construction of the Bolivian portion of the project

  3. Airborne gamma-ray spectrometer and magnetometer survey, Durango A, Colorado. Final report Volume II A. Detail area

    International Nuclear Information System (INIS)

    1983-01-01

    This volume contains geology of the Durango A detail area, radioactive mineral occurences in Colorado, and geophysical data interpretation. Eight appendices provide the following: stacked profiles, geologic histograms, geochemical histograms, speed and altitude histograms, geologic statistical tables, geochemical statistical tables, magnetic and ancillary profiles, and test line data

  4. Conceptual Elements: A Detailed Framework to Support and Assess Student Learning of Biology Core Concepts

    Science.gov (United States)

    Cary, Tawnya; Branchaw, Janet

    2017-01-01

    The Vision and Change in Undergraduate Biology Education: Call to Action report has inspired and supported a nationwide movement to restructure undergraduate biology curricula to address overarching disciplinary concepts and competencies. The report outlines the concepts and competencies generally but does not provide a detailed framework to guide the development of the learning outcomes, instructional materials, and assessment instruments needed to create a reformed biology curriculum. In this essay, we present a detailed Vision and Change core concept framework that articulates key components that transcend subdisciplines and scales for each overarching biological concept, the Conceptual Elements (CE) Framework. The CE Framework was developed using a grassroots approach of iterative revision and incorporates feedback from more than 60 biologists and undergraduate biology educators from across the United States. The final validation step resulted in strong national consensus, with greater than 92% of responders agreeing that each core concept list was ready for use by the biological sciences community, as determined by scientific accuracy and completeness. In addition, we describe in detail how educators and departments can use the CE Framework to guide and document reformation of individual courses as well as entire curricula. PMID:28450444

  5. Legionnaires’ Disease and Compost

    Centers for Disease Control (CDC) Podcasts

    2017-09-27

    Dr. Brian Raphael, a CDC research microbiologist, discusses Legionella bacteria in compost.  Created: 9/27/2017 by National Center for Emerging and Zoonotic Infectious Diseases (NCEZID).   Date Released: 9/27/2017.

  6. 2295-IJBCS-Article-Sylvester Okorondu

    African Journals Online (AJOL)

    hp

    Int. J. Biol. Chem. Sci. 9(2): 1038-1049, April 2015. ISSN 1997-342X (Online), ISSN 1991-8631 (Print) .... method of generating energy (electricity) from wastewater. ..... methods applied in this work. ... Microbiologists, Environmental Engineers.

  7. 16 CFR 1750.5 - Detailed requirements.

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Detailed requirements. 1750.5 Section 1750.5 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION REFRIGERATOR SAFETY ACT REGULATIONS STANDARD FOR... directed perpendicularly to the plane of the door and applied anywhere along the latch edge of the inside...

  8. Use of Academic Detailing With Audit and Feedback to Improve Antipsychotic Pharmacotherapy.

    Science.gov (United States)

    Brunette, Mary F; Cotes, Robert O; de Nesnera, Alexander; McHugo, Gregory; Dzebisashvili, Nino; Xie, Haiyi; Bartels, Stephen J

    2018-06-08

    Second-generation antipsychotics vary in their propensity to cause serious cardiometabolic side effects. In addition, use of two or more antipsychotics (polypharmacy) may lead to additive side effects and has not been shown to be consistently more effective than monotherapy. This study examined the use of academic detailing with audit and feedback to improve antipsychotic prescribing practices, including antipsychotic polypharmacy and utilization of medication with high or low risk of cardiometabolic side effects ("high risk" or "low risk," respectively). Four intervention sessions were provided over two years to psychiatric care providers at community mental health centers. Segmented regression within the general estimating equation model framework used Medicaid pharmacy claims to examine prescribing patterns before and after the intervention among all beneficiaries (67,721 person-months) over a five-year period. After the intervention, 10.9% of beneficiaries with antipsychotic claims were on polypharmacy, compared with 13.1% before the invention. Use of high-risk and low-risk antipsychotics did not change. The final adjusted polypharmacy model showed that antipsychotic polypharmacy decreased among young adults and adults ages 40 or older compared with beneficiaries ages 30-39 (β=-.02, p=.04, and β=-.02, p=.007, respectively). The raw proportion of beneficiaries on high- and low-risk agents did not change, although final adjusted models demonstrated changes in use of high- and low-risk agents by diagnosis and risk group. Polypharmacy decreased among young and older adults after academic detailing with audit and feedback. Although further research is needed, this low-intensity intervention may help mental health systems reduce antipsychotic polypharmacy.

  9. APT Blanket Detailed Bin Model Based on Initial Plate-Type Design -3D FLOWTRAN-TF Model

    International Nuclear Information System (INIS)

    Hamm, L.L.

    1998-01-01

    This report provides background information for a series of reports documenting accident scenario simulations for the Accelerator Production of Tritium (APT) blanket heat removal systems. The simulations were performed in support of the Preliminary Safety Analysis Report for the APT. This report gives a brief description of the FLOWTRAN-TF code which was used for detailed blanket bin modeling

  10. Specificity and detail in autobiographical memory: Same or different constructs?

    Science.gov (United States)

    Kyung, Yoonhee; Yanes-Lukin, Paula; Roberts, John E

    2016-01-01

    Research on autobiographical memory has focused on whether memories are coded as specific (i.e., describe a single event that happened at a particular time and place). Although some theory and research suggests that the amount of detail in autobiographical memories reflects a similar underlying construct as memory specificity, past research has not investigated whether these variables converge. Therefore, the present study compared the proportion of specific memories and the amount of detail embedded in memory responses to cue words. Results demonstrated that memory detail and proportion of specific memories were not correlated with each other and showed different patterns of association with other conceptually relevant variables. When responses to neutral cue words were examined in multiple linear and logistic regression analyses, the proportion of specific memories uniquely predicted less depressive symptoms, low emotional avoidance, lower emotion reactivity, better executive control and lower rumination, whereas the amount of memory detail uniquely predicted the presence of depression diagnosis, as well as greater depressive symptoms, subjective stress, emotion reactivity and rumination. Findings suggest that the ability to retrieve specific memories and the tendency to retrieve detailed personal memories reflect different constructs that have different implications in the development of emotional distress.

  11. Optoelectronic pH Meter: Further Details

    Science.gov (United States)

    Jeevarajan, Antony S.; Anderson, Mejody M.; Macatangay, Ariel V.

    2009-01-01

    A collection of documents provides further detailed information about an optoelectronic instrument that measures the pH of an aqueous cell-culture medium to within 0.1 unit in the range from 6.5 to 7.5. The instrument at an earlier stage of development was reported in Optoelectronic Instrument Monitors pH in a Culture Medium (MSC-23107), NASA Tech Briefs, Vol. 28, No. 9 (September 2004), page 4a. To recapitulate: The instrument includes a quartz cuvette through which the medium flows as it is circulated through a bioreactor. The medium contains some phenol red, which is an organic pH-indicator dye. The cuvette sits between a light source and a photodetector. [The light source in the earlier version comprised red (625 nm) and green (558 nm) light-emitting diodes (LEDs); the light source in the present version comprises a single green- (560 nm)-or-red (623 nm) LED.] The red and green are repeatedly flashed in alternation. The responses of the photodiode to the green and red are processed electronically to obtain the ratio between the amounts of green and red light transmitted through the medium. The optical absorbance of the phenol red in the green light varies as a known function of pH. Hence, the pH of the medium can be calculated from the aforesaid ratio.

  12. Detailed Safety Review of Anthrax Vaccine Adsorbed

    National Research Council Canada - National Science Library

    2001-01-01

    To date, 18 human studies have assessed the safety of anthrax vaccination. These studies, some stretching back almost 50 years, reported adverse events after vaccination in varying degrees of detail...

  13. Detailed Electrochemical Characterisation of Large SOFC Stacks

    DEFF Research Database (Denmark)

    Mosbæk, Rasmus Rode; Hjelm, Johan; Barfod, R.

    2012-01-01

    application of advanced methods for detailed electrochemical characterisation during operation. An operating stack is subject to steep compositional gradients in the gaseous reactant streams, and significant temperature gradients across each cell and across the stack, which makes it a complex system...... Fuel Cell A/S was characterised in detail using electrochemical impedance spectroscopy. An investigation of the optimal geometrical placement of the current probes and voltage probes was carried out in order to minimise measurement errors caused by stray impedances. Unwanted stray impedances...... are particularly problematic at high frequencies. Stray impedances may be caused by mutual inductance and stray capacitance in the geometrical set-up and do not describe the fuel cell. Three different stack geometries were investigated by electrochemical impedance spectroscopy. Impedance measurements were carried...

  14. Think Fungus

    Centers for Disease Control (CDC) Podcasts

    2013-09-23

    Dr. Mary Brandt, a CDC research microbiologist, discusses the impact of fungal infections.  Created: 9/23/2013 by National Center for Emerging and Zoonotic Infectious Diseases (NCEZID).   Date Released: 9/24/2013.

  15. Invasive Meningococcal Men Y Disease

    Centers for Disease Control (CDC) Podcasts

    2012-04-18

    Dr. Leonard Mayer, a public health microbiologist at CDC, discusses invasive meningococcal disease.  Created: 4/18/2012 by National Center for Emerging and Zoonotic Infectious Diseases (NCEZID).   Date Released: 4/23/2012.

  16. Detailed Physical Trough Model for NREL's Solar Advisor Model: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Wagner, M. J.; Blair, N.; Dobos, A.

    2010-10-01

    Solar Advisor Model (SAM) is a free software package made available by the National Renewable Energy Laboratory (NREL), Sandia National Laboratory, and the US Department of Energy. SAM contains hourly system performance and economic models for concentrating solar power (CSP) systems, photovoltaic, solar hot-water, and generic fuel-use technologies. Versions of SAM prior to 2010 included only the parabolic trough model based on Excelergy. This model uses top-level empirical performance curves to characterize plant behavior, and thus is limited in predictive capability for new technologies or component configurations. To address this and other functionality challenges, a new trough model; derived from physical first principles was commissioned to supplement the Excelergy-based empirical model. This new 'physical model' approaches the task of characterizing the performance of the whole parabolic trough plant by replacing empirical curve-fit relationships with more detailed calculations where practical. The resulting model matches the annual performance of the SAM empirical model (which has been previously verified with plant data) while maintaining run-times compatible with parametric analysis, adding additional flexibility in modeled system configurations, and providing more detailed performance calculations in the solar field, power block, piping, and storage subsystems.

  17. Study on detailed geological modelling for fluvial sandstone reservoir in Daqing oil field

    Energy Technology Data Exchange (ETDEWEB)

    Zhao Hanqing; Fu Zhiguo; Lu Xiaoguang [Institute of Petroleum Exploration and Development, Daqing (China)

    1997-08-01

    Guided by the sedimentation theory and knowledge of modern and ancient fluvial deposition and utilizing the abundant information of sedimentary series, microfacies type and petrophysical parameters from well logging curves of close spaced thousands of wells located in a large area. A new method for establishing detailed sedimentation and permeability distribution models for fluvial reservoirs have been developed successfully. This study aimed at the geometry and internal architecture of sandbodies, in accordance to their hierarchical levels of heterogeneity and building up sedimentation and permeability distribution models of fluvial reservoirs, describing the reservoir heterogeneity on the light of the river sedimentary rules. The results and methods obtained in outcrop and modem sedimentation studies have successfully supported the study. Taking advantage of this method, the major producing layers (PI{sub 1-2}), which have been considered as heterogeneous and thick fluvial reservoirs extending widely in lateral are researched in detail. These layers are subdivided into single sedimentary units vertically and the microfacies are identified horizontally. Furthermore, a complex system is recognized according to their hierarchical levels from large to small, meander belt, single channel sandbody, meander scroll, point bar, and lateral accretion bodies of point bar. The achieved results improved the description of areal distribution of point bar sandbodies, provide an accurate and detailed framework model for establishing high resolution predicting model. By using geostatistic technique, it also plays an important role in searching for enriched zone of residual oil distribution.

  18. Study on Detailing Design of Precast Concrete Frame Structure

    Science.gov (United States)

    Lida, Tian; Liming, Li; Kang, Liu; Jiao, Geng; Ming, Li

    2018-03-01

    Taking a certain precast concrete frame structure as an example, this paper introduces the general procedures and key points in detailing design of emulative cast-in-place prefabricated structure from the aspects of structural scheme, precast element layout, shop drawing design and BIM 3D modelling. This paper gives a practical solution for the detailing design of precast concrete frame structure under structural design codes in China.

  19. Cleaner combustion developing detailed chemical kinetic models

    CERN Document Server

    Battin-Leclerc, Frédérique; Simmie, John M

    2013-01-01

    This book describes the reactive chemistry of minor pollutants within extensively validated detailed mechanisms for traditional fuels, and also for innovative surrogates, describing the complex chemistry of new, environmentally important bio-fuels.

  20. Preliminary evaluation of crisis-relocation fallout-shelter options. Volume 2. Detailed analysis

    Energy Technology Data Exchange (ETDEWEB)

    Santini, D.J.; Clinch, J.M.; Davis, F.H.; Hill, L.G.; Lynch, E.P.; Tanzman, E.A.; Wernette, D.R.

    1982-12-01

    This report presents a preliminary, detailed evaluation of various shelter options for use if the President orders crisis relocation of the US urban population because of strong expectation of a nuclear war. The availability of livable shelter space at 40 ft/sup 2/ per person (congregate-care space) by state is evaluated. Options are evaluated for construction of fallout shelters allowing 10 ft/sup 2/ per person - such shelters are designed to provide 100% survival at projected levels of radioactive fallout. The FEMA concept of upgrading existing buildings to act as fallout shelters can, in principle, provide adequate shelter throughout most of the US. Exceptions are noted and remedies proposed. In terms of upgrading existing buildings to fallout shelter status, great benefits are possible by turning away from a standard national approach and adopting a more site-specific approach. Existing FEMA research provides a solid foundation for successful crisis relocation planning, but the program can be refined by making suitable modifications in its locational, engineering, and institutionally specific elements.

  1. 46 CFR 160.013-3 - Materials, workmanship, and construction details.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Materials, workmanship, and construction details. 160.013-3 Section 160.013-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) EQUIPMENT... materials, workmanship, and construction details shall be in substantial compliance with the provisions of...

  2. Unrevealing culture-negative severe sepsis

    OpenAIRE

    de Prost, Nicolas; Razazi, Keyvan; Brun-Buisson, Christian

    2013-01-01

    Sepsis involves a wide array of sources and microorganisms, only a fraction of which are microbiologically documented. Culture-negative sepsis poses special diagnostic challenges to both clinicians and microbiologists and further questions the validity of sepsis definitions.

  3. Genetic programming in microorganisms

    Energy Technology Data Exchange (ETDEWEB)

    Hopwood, D A

    1981-11-01

    Formerly, when microbiologists had only existing organisms at their disposal whose characteristics could only be changed randomly by genetic experiments, they used to dream of programmed genetic changes. This dream has come true with modern genetic engineering.

  4. Detailed description of an SSAC at the facility level for research laboratory facilities

    International Nuclear Information System (INIS)

    Jones, R.J.

    1985-08-01

    The purpose of this document is to provide a detailed description of a system for the accounting for and control of nuclear material in a research laboratory facility which can be used by a facility operator to establish his own system to comply with a national system for nuclear material accounting and control and to facilitate application of IAEA safeguards. The scope of this document is limited to descriptions of the following SSAC elements: (1) Nuclear Material Measurements; (2) Measurement Quality; (3) Records and Reports; (4) Physical Inventory Taking; (5) Material Balance Closing

  5. Detailed Design Documentation, without the Pain

    Science.gov (United States)

    Ramsay, C. D.; Parkes, S.

    2004-06-01

    Producing detailed forms of design documentation, such as pseudocode and structured flowcharts, to describe the procedures of a software system:(1) allows software developers to model and discuss their understanding of a problem and the design of a solution free from the syntax of a programming language,(2) facilitates deeper involvement of non-technical stakeholders, such as the customer or project managers, whose influence ensures the quality, correctness and timeliness of the resulting system,(3) forms comprehensive documentation of the system for its future maintenance, reuse and/or redeployment.However, such forms of documentation require effort to create and maintain.This paper describes a software tool which is currently being developed within the Space Systems Research Group at the University of Dundee which aims to improve the utility of, and the incentive for, creating detailed design documentation for the procedures of a software system. The rationale for creating such a tool is briefly discussed, followed by a description of the tool itself, a summary of its perceived benefits, and plans for future work.

  6. Stream sediment detailed geochemical survey for Marysvale, Utah

    International Nuclear Information System (INIS)

    Butz, T.R.; Vreeland, J.L.; Bard, C.S.; Helgerson, R.N.; Grimes, J.G.; Pritz, P.M.

    1980-01-01

    Results of the Marysvale detailed geochemical survey are reported. Field and laboratory data are presented for 397 stream sediment samples and 160 radiometric readings. Statistical and areal distributions of uranium and possible uranium-related variables are displayed. A generalized geologic map of the area is provided, and pertinent geologic factors which may be of significance in evaluating the potential for uranium mineralization are briefly discussed. Stream sediments containing significant amounts of soluble uranium (greater than or equal to 16.93 ppM) occur in numerous areas, the most prevalent being in the western portion of the survey area, within and surrounding the Mount Belknap Caldera. Thorium, beryllium, cerium, manganese, molybdenum, niobium, potassium, yttrium, zinc, and zirconium occur in concentrations greater than or equal to 84th percentile in many sediment samples taken from within and surrounding the Mount Belknap Caldera. The uranium and related variables are associated with highly silicic intrusions and extrusions of the Mount Belknap Volcanics, as well as hydrothermal activity which has occurred in the Marysvale volcanic field

  7. An exposure-response database for detailed toxicity data

    International Nuclear Information System (INIS)

    Woodall, George M.

    2008-01-01

    Risk assessment for human health effects often depends on evaluation of toxicological literature from a variety of sources. Risk assessors have limited resources for obtaining raw data, performing follow-on analyses or initiating new studies. These constraints must be balanced against a need to improve scientific credibility through improved statistical and analytical methods that optimize the use of available information. Computerized databases are used in toxicological risk assessment both for storing data and performing predictive analyses. Many systems provide primarily either bibliographic information or summary factual data from toxicological studies; few provide adequate information to allow application of dose-response models. The Exposure-Response database (ERDB) described here fills this gap by allowing entry of sufficiently detailed information on experimental design and results for each study, while limiting data entry to the most relevant. ERDB was designed to contain information from the open literature to support dose-response assessment and allow a high level of automation in performance of various types of dose-response analyses. Specifically, ERDB supports emerging analytical approaches for dose-response assessment, while accommodating the diverse nature of published literature. Exposure and response data are accessible in a relational multi-table design, with closely controlled standard fields for recording values and free-text fields to describe unique aspects of the study. Additional comparative analyses are made possible through summary tables and graphic representations of the data contained within ERDB

  8. Description of the detailed Functional Architecture of the Frequency and Voltage control solution (functional and information layer)

    DEFF Research Database (Denmark)

    Caerts, Chris; Rikos, Evangelos; Syed, Mazheruddin

    2017-01-01

    This D4.2 document provides the description of the detailed functional architecture of the selected solutions that will be implemented and tested. This is documented by combining a function-based IEC 62559 Use Case description with an SGAM mapping of these functions and the interactions among...... these functions on the Function and Information layer....

  9. Generic Reliability-Based Inspection Planning for Fatigue Sensitive Details

    DEFF Research Database (Denmark)

    Sørensen, John Dalsgaard; Straub, Daniel; Faber, Michael Havbro

    2005-01-01

    of fatigue sensitive details in fixed offshore steel jacket platforms and FPSO ship structures. Inspection and maintenance activities are planned such that code based requirements to the safety of personnel and environment for the considered structure are fulfilled and at the same time such that the overall......The generic approach for planning of in-service NDT inspections is extended to cover the case where the fatigue load is modified during the design lifetime of the structure. Generic reliability-based inspection planning has been developed as a practical approach to perform inspection planning...... expected costs for design, inspections, repairs and failures are minimized. The method is based on the assumption of “no-finds” of cracks during inspections. Each fatigue sensitive detail is categorized according to their type of details (SN curves), FDF values, RSR values, inspection, repair and failure...

  10. 'Gatekeeper' unit defeats legionella.

    Science.gov (United States)

    Wolters, Jo

    2007-03-01

    Legionella presents an ongoing cause for concern in any sector where duty of care responsibilities prevail. Jo Wolters, microbiologist and sector head of TA-Aqua+ at Tour & Andersson, describes a recently developed method of legionella prevention and control.

  11. Pulsed-field Gel Electrophoresis for Salmonella Infection Surveillance, Texas, USA, 2007

    Centers for Disease Control (CDC) Podcasts

    This podcast describes monitoring of the use of pulsed-field gel electrophoresis for Salmonella surveillance in Houston, Texas. CDC microbiologist Peter Gerner-Smidt discusses the importance of the PulseNet national database in surveillance of food-borne infections.

  12. Combined preliminary–detailed design of wind turbines

    Directory of Open Access Journals (Sweden)

    P. Bortolotti

    2016-05-01

    Full Text Available This paper is concerned with the holistic optimization of wind turbines. A multi-disciplinary optimization procedure is presented that marries the overall sizing of the machine in terms of rotor diameter and tower height (often termed “preliminary design” with the detailed sizing of its aerodynamic and structural components. The proposed combined preliminary–detailed approach sizes the overall machine while taking into full account the subtle and complicated couplings that arise due to the mutual effects of aerodynamic and structural choices. Since controls play a central role in dictating performance and loads, control laws are also updated accordingly during optimization. As part of the approach, rotor and tower are sized simultaneously, even in this case capturing the mutual effects of one component over the other due to the tip clearance constraint. The procedure, here driven by detailed models of the cost of energy, results in a complete aero-structural design of the machine, including its associated control laws. The proposed methods are tested on the redesign of two wind turbines, a 2.2 MW onshore machine and a large 10 MW offshore one. In both cases, the optimization leads to significant changes with respect to the initial baseline configurations, with noticeable reductions in the cost of energy. The novel procedures are also exercised on the design of low-induction rotors for both considered wind turbines, showing that they are typically not competitive with conventional high-efficiency rotors.

  13. Supercomputing Centers and Electricity Service Providers

    DEFF Research Database (Denmark)

    Patki, Tapasya; Bates, Natalie; Ghatikar, Girish

    2016-01-01

    from a detailed, quantitative survey-based analysis and compare the perspectives of the European grid and SCs to the ones of the United States (US). We then show that contrary to the expectation, SCs in the US are more open toward cooperating and developing demand-management strategies with their ESPs......Supercomputing Centers (SCs) have high and variable power demands, which increase the challenges of the Electricity Service Providers (ESPs) with regards to efficient electricity distribution and reliable grid operation. High penetration of renewable energy generation further exacerbates...... this problem. In order to develop a symbiotic relationship between the SCs and their ESPs and to support effective power management at all levels, it is critical to understand and analyze how the existing relationships were formed and how these are expected to evolve. In this paper, we first present results...

  14. Exploring Service-led Growth Trajectories for Analytical Equipment Providers

    DEFF Research Database (Denmark)

    Raja, Jawwad; Frandsen, Thomas; Mouritsen, Jan

    2016-01-01

    This paper examines the dilemmas encountered by advanced analytical equipment providers in developing service-led growth strategies to expand their business in pursuit of more attractive revenue models. It does so by adopting a case based research approach. The findings detail the capabilities...... and solutions-in different contexts, with a view to expanding markets and developing solution based business models, are discussed. It is argued that analytical equipment providers encounter dilemmas as managing these different trajectories implies different needs in terms of the technological sophistication...... of equipment required. This does not necessarily imply that one context is less complex than the other, but rather suggests that the role of integration is qualitatively different and that the relationship between product and service varies when developing solutions in these different arenas....

  15. Collaborative recall of details of an emotional film.

    Science.gov (United States)

    Wessel, Ineke; Zandstra, Anna Roos E; Hengeveld, Hester M E; Moulds, Michelle L

    2015-01-01

    Collaborative inhibition refers to the phenomenon that when several people work together to produce a single memory report, they typically produce fewer items than when the unique items in the individual reports of the same number of participants are combined (i.e., nominal recall). Yet, apart from this negative effect, collaboration may be beneficial in that group members remove errors from a collaborative report. Collaborative inhibition studies on memory for emotional stimuli are scarce. Therefore, the present study examined both collaborative inhibition and collaborative error reduction in the recall of the details of emotional material in a laboratory setting. Female undergraduates (n = 111) viewed a film clip of a fatal accident and subsequently engaged in either collaborative (n = 57) or individual recall (n = 54) in groups of three. The results show that, across several detail categories, collaborating groups recalled fewer details than nominal groups. However, overall, nominal recall produced more errors than collaborative recall. The present results extend earlier findings on both collaborative inhibition and error reduction to the recall of affectively laden material. These findings may have implications for the applied fields of forensic and clinical psychology.

  16. RARE OCCURRENCE OF HETEROTROPHIC BACTERIA WITH PATHOGENIC POTENTIAL IN POTABLE WATER

    Science.gov (United States)

    Since the discovery of Legionella pneumophila, an opportunistic pathogen that is indigenous to water, microbiologists have speculated that there may be other opportunistic pathogens among the numerous heterotrophic bacteria found in potable water. The USEPA developed a series of...

  17. Detailed clinical models: a review.

    Science.gov (United States)

    Goossen, William; Goossen-Baremans, Anneke; van der Zel, Michael

    2010-12-01

    Due to the increasing use of electronic patient records and other health care information technology, we see an increase in requests to utilize these data. A highly level of standardization is required during the gathering of these data in the clinical context in order to use it for analyses. Detailed Clinical Models (DCM) have been created toward this purpose and several initiatives have been implemented in various parts of the world to create standardized models. This paper presents a review of DCM. Two types of analyses are presented; one comparing DCM against health care information architectures and a second bottom up approach from concept analysis to representation. In addition core parts of the draft ISO standard 13972 on DCM are used such as clinician involvement, data element specification, modeling, meta information, and repository and governance. SIX INITIATIVES WERE SELECTED: Intermountain Healthcare, 13606/OpenEHR Archetypes, Clinical Templates, Clinical Contents Models, Health Level 7 templates, and Dutch Detailed Clinical Models. Each model selected was reviewed for their overall development, involvement of clinicians, use of data types, code bindings, expressing semantics, modeling, meta information, use of repository and governance. Using both a top down and bottom up approach to comparison reveals many commonalties and differences between initiatives. Important differences include the use of or lack of a reference model and expressiveness of models. Applying clinical data element standards facilitates the use of conceptual DCM models in different technical representations.

  18. ACCOUNTING TREATMENTS USED FOR ACCOUNTING SERVICES PROVIDERS

    Directory of Open Access Journals (Sweden)

    ŢOGOE GRETI DANIELA

    2014-08-01

    Full Text Available The theme of our research is the ways of keeping accounting entities that are the object of the provision of services in the accounting profession. This paper aims to achieve a parallel between the ways of organizing financial records - accounting provided by freelancers and companies with activity in the financial - accounting. The first step in our scientific research is to establish objectives chosen area of scientific knowledge. Our scientific approach seeks to explain through a thorough and detailed approach as different sides (conceptual and practical looking projections of accounting issues related to regulatory developments and practices in the field. This paper addresses various concepts, accounting treatments, and books and accounting documents used both freelancers in providing accounting services and legal persons authorized accounting profession. In terms of methodology and research perspective, the whole scientific approach combined with quantitative and qualitative research theoretical perspective (descriptive-conceptual with practice perspective (empirical analyzing the main contributions of various authors (Romanian and foreign to knowledge in the field. Following the survey believe that the amendments to the national legislation will support entities providing accounting services, by cutting red tape on Administrative Burdens, and consequently will increase profitability and increase service quality.

  19. THULE: A detailed description

    International Nuclear Information System (INIS)

    Terry, M.J.

    1964-07-01

    This report describes the THULE scheme of lattice physics calculation which has been developed in FORTRAN for the IBM 7090. This scheme predicts the neutron flux over energy and space, for many groups and regions, together with reactivity and reaction rate edits for both a single lattice cell and a reactor core. This report describes in detail the input requirements for the THULE programme which forms the main part of the scheme. Brief descriptions of the 7090 programmes TED 6 and NOAH are included as appendices. TED 6 will produce the THULE edits from a WDSN output tape and NOAH is a version of the METHUSELAH programme which contains many of the THULE edits and will also produce input cards for THULE. (author)

  20. Measurement and control of detailed electronic properties in a single molecule break junction.

    Science.gov (United States)

    Wang, Kun; Hamill, Joseph; Zhou, Jianfeng; Guo, Cunlan; Xu, Bingqian

    2014-01-01

    The lack of detailed experimental controls has been one of the major obstacles hindering progress in molecular electronics. While large fluctuations have been occurring in the experimental data, specific details, related mechanisms, and data analysis techniques are in high demand to promote our physical understanding at the single-molecule level. A series of modulations we recently developed, based on traditional scanning probe microscopy break junctions (SPMBJs), have helped to discover significant properties in detail which are hidden in the contact interfaces of a single-molecule break junction (SMBJ). For example, in the past we have shown that the correlated force and conductance changes under the saw tooth modulation and stretch-hold mode of PZT movement revealed inherent differences in the contact geometries of a molecular junction. In this paper, using a bias-modulated SPMBJ and utilizing emerging data analysis techniques, we report on the measurement of the altered alignment of the HOMO of benzene molecules with changing the anchoring group which coupled the molecule to metal electrodes. Further calculations based on Landauer fitting and transition voltage spectroscopy (TVS) demonstrated the effects of modulated bias on the location of the frontier molecular orbitals. Understanding the alignment of the molecular orbitals with the Fermi level of the electrodes is essential for understanding the behaviour of SMBJs and for the future design of more complex devices. With these modulations and analysis techniques, fruitful information has been found about the nature of the metal-molecule junction, providing us insightful clues towards the next step for in-depth study.

  1. Medicare Provider Data - Hospice Providers

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Hospice Utilization and Payment Public Use File provides information on services provided to Medicare beneficiaries by hospice providers. The Hospice PUF...

  2. Hiring appropriate providers for different populations: acute care nurse practitioners.

    Science.gov (United States)

    Haut, Cathy; Madden, Maureen

    2015-06-01

    Acute care nurse practitioners, prepared as providers for a variety of populations of patients, continue to make substantial contributions to health care. Evidence indicates shorter stays, higher satisfaction among patients, increased work efficiency, and higher quality outcomes when acute care nurse practitioners are part of unit- or service-based provider teams. The Consensus Model for APRN Regulation: Licensure, Accreditation, Certification, and Education outlines detailed guidelines for matching nurse practitioners' education with certification and practice by using a population-focused algorithm. Despite national support for the model, nurse practitioners and employers continue to struggle with finding the right fit. Nurse practitioners often use their interest and previous nursing experience to apply for an available position, and hospitals may not understand preparation or regulations related to matching the appropriate provider to the work environment. Evidence and regulatory guidelines indicate appropriate providers for population-focused positions. This article presents history and recommendations for hiring acute care nurse practitioners as providers for different populations of patients. ©2015 American Association of Critical-Care Nurses.

  3. Application of Detailed Chemical Kinetics to Combustion Instability Modeling

    Science.gov (United States)

    2016-01-04

    Clearance Number 15692 Clearance Date 12/3/2015 14. ABSTRACT A comparison of a single step global reaction and the detailed GRI -Mech 1.2 for combustion...comparison of a single step global reaction and the detailed GRI -Mech 1.2 for com- bustion instability modeling in a methane-fueled longitudinal-mode...methane as the fuel. We use the GRI -Mech 1.2 kinetics mechanism for methane oxidation.11 The GRI -Mech 1.2 was chosen over 2.11 because the only

  4. Structural concepts and details for seismic design

    International Nuclear Information System (INIS)

    Johnson, M.W.; Smietana, E.A.; Murray, R.C.

    1991-01-01

    As a part of the DOE Natural Phenomena Hazards Program, a new manual has been developed, entitled UCRL-CR-106554, open-quotes Structural Concepts and Details for Seismic Design.close quotes This manual describes and illustrates good practice for seismic-resistant design

  5. Engineering of obligate intracellular bacteria: progress, challenges and paradigms

    Science.gov (United States)

    Over twenty years have passed since the first report of genetic manipulation of an obligate intracellular bacterium. Through progress interspersed by bouts of stagnation, microbiologists and geneticists have developed approaches to genetically manipulate obligates. A brief overview of the current ge...

  6. Bacteria and Archaea in acidic environments and a key to morphological identification

    Science.gov (United States)

    Robbins, E.I.

    2000-01-01

    Natural and anthropogenic acidic environments are dominated by bacteria and Archaea. As many as 86 genera or species have been identified or isolated from pH morphological characteristics, habitat information and a key for light microscope identification for the non-microbiologist.

  7. Monitoring the potential introduction of the Swedish Chlamydia trachomatis variant (swCT) in the Netherlands

    NARCIS (Netherlands)

    Morré, S. A.; Catsburg, A.; de Boer, M.; Spaargaren, J.; de Vries, H. J. C.; Schirm, J.; Savelkoul, P. H. M.; van Steenbergen, J.; Swaan, C.

    2007-01-01

    This report describes the actions of public health experts in cooperation with specialists in sexually transmitted diseases (STD), epidemiologists and (molecular) microbiologists to investigate the possible introduction of the swCT variant in the Netherlands: 1. Investigating trends in CT

  8. Understanding the behavior of foodborne pathogens in the food chain

    DEFF Research Database (Denmark)

    Rantsiou, Kalliopi; Mataragas, Marios; Jespersen, Lene

    2011-01-01

    In recent years and with the significant advancements in instrumentation for molecular biology methods, the focus of food microbiologists, dealing with pathogenic microorganisms in foods, is shifting. Scientists specifically aim at elucidating the effect that the food composition, as well...

  9. Trajectory control sensor engineering model detailed test objective

    Science.gov (United States)

    Dekome, Kent; Barr, Joseph Martin

    1991-01-01

    The concept employed in an existing Trajectory Control Sensor (TCS) breadboard is being developed into an engineering model to be considered for flight on the Shuttle as a Detailed Test Objective (DTO). The sensor design addresses the needs of Shuttle/SSF docking/berthing by providing relative range and range rate to 1500 meters as well as the perceived needs of AR&C by relative attitude measurement over the last 100 meters. Range measurement is determined using a four-tone ranging technique. The Doppler shift on the highest frequency tone will be used to provide direct measurement of range rate. Bearing rate and attitude rates will be determined through back differencing of bearing and attitude, respectively. The target consists of an isosceles triangle configuration of three optical retroreflectors, roughly one meter and one-half meter in size. After target acquisition, the sensor continually updates the positions of the three retros at a rate of about one hertz. The engineering model is expected to weigh about 25 pounds, consume 25-30 watts, and have an envelope of about 1.25 cubic feet. The following concerns were addressed during the presentation: are there any concerns with differentiating attitude and bearing to get attitude and bearing rates? Since the docking scenario has low data bandwidth, back differencing is a sufficient approximation of a perfect differentiator for this application. Could range data be obtained if there were no retroreflectors on the target vehicle? Possibly, but only at close range. It would be dependent on target characteristics.

  10. Terry Turbopump Expanded Operating Band Full-Scale Component and Basic Science Detailed Test Plan - Final.

    Energy Technology Data Exchange (ETDEWEB)

    Osborn, Douglas [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Solom, Matthew [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-02-01

    This document details the milestone approach to define the true operating limitations (margins) of the Terry turbopump systems used in the nuclear industry for Milestone 3 (full-scale component experiments) and Milestone 4 (Terry turbopump basic science experiments) efforts. The overall multinational-sponsored program creates the technical basis to: (1) reduce and defer additional utility costs, (2) simplify plant operations, and (3) provide a better understanding of the true margin which could reduce overall risk of operations.

  11. Detailed numerical simulations of laser cooling processes

    Science.gov (United States)

    Ramirez-Serrano, J.; Kohel, J.; Thompson, R.; Yu, N.

    2001-01-01

    We developed a detailed semiclassical numerical code of the forces applied on atoms in optical and magnetic fields to increase the understanding of the different roles that light, atomic collisions, background pressure, and number of particles play in experiments with laser cooled and trapped atoms.

  12. Detailed description of an SSAC at the facility level for light water moderated (off-load refueled) power reactor facilities

    International Nuclear Information System (INIS)

    Jones, R.J.

    1985-03-01

    This report is intended to provide the technical details of an effective State Systems of Accounting for and Control of Nuclear Material (SSAC) which Member States may use, if they wish, to establish and maintain their SSACs. It is expected that systems designed along the lines described would be effective in meeting the objectives of both national and international systems for nuclear material accounting and control. This document accordingly provides a detailed description of a system for the accounting for and control of nuclear material in an off-load refueled light water moderated power reactor facility which can be used by a facility operator to establish his own system to comply with a national system for nuclear material accounting and control and to facilitate application of IAEA safeguards. The scope of this document is limited to descriptions of the following elements: (1) Nuclear Material Measurements; (2) Measurement Quality; (3) Records and Reports; (4) Physical Inventory Taking; (5) Material Balance Closing

  13. Mathematical Model of Induction Heating Processes in Axial Symmetric Inductor-Detail Systems

    Directory of Open Access Journals (Sweden)

    Maik Streblau

    2014-05-01

    Full Text Available The wide variety of models for analysis of processes in the inductor-detail systems makes it necessary to summarize them. This is a difficult task because of the variety of inductor-detail system configurations. This paper aims to present a multi physics mathematical model for complex analysis of electromagnetic and thermal fields in axial symmetric systems inductor-detail.

  14. Analysis of local influences in structural details of the bridges

    Directory of Open Access Journals (Sweden)

    Adam RUDZIK

    2015-03-01

    Full Text Available The article analyses the problems of local influences in structural details of bridges as the critical locations, whose damages or excessive force may directly affect the safety of users. These analyses are shown on selected examples. Presented is the example of local changes in the forms of proper vibrations in the node of the truss bridge that can be used in expert issues concerning the causes of damages. The second example are the changes in stresses in the stay cable anchorage element including the nonlinear material models. Models of this type can be successfully used by engineers as they allow for analysis of selected structural details without the need for detailed mapping of the entire structure, but only a selected section.

  15. Incorporation of detailed eye model into polygon-mesh versions of ICRP-110 reference phantoms.

    Science.gov (United States)

    Nguyen, Thang Tat; Yeom, Yeon Soo; Kim, Han Sung; Wang, Zhao Jun; Han, Min Cheol; Kim, Chan Hyeong; Lee, Jai Ki; Zankl, Maria; Petoussi-Henss, Nina; Bolch, Wesley E; Lee, Choonsik; Chung, Beom Sun

    2015-11-21

    The dose coefficients for the eye lens reported in ICRP 2010 Publication 116 were calculated using both a stylized model and the ICRP-110 reference phantoms, according to the type of radiation, energy, and irradiation geometry. To maintain consistency of lens dose assessment, in the present study we incorporated the ICRP-116 detailed eye model into the converted polygon-mesh (PM) version of the ICRP-110 reference phantoms. After the incorporation, the dose coefficients for the eye lens were calculated and compared with those of the ICRP-116 data. The results showed generally a good agreement between the newly calculated lens dose coefficients and the values of ICRP 2010 Publication 116. Significant differences were found for some irradiation cases due mainly to the use of different types of phantoms. Considering that the PM version of the ICRP-110 reference phantoms preserve the original topology of the ICRP-110 reference phantoms, it is believed that the PM version phantoms, along with the detailed eye model, provide more reliable and consistent dose coefficients for the eye lens.

  16. Satisfying the needs of Japanese cancer patients: a comparative study of detailed and standard informed consent documents.

    Science.gov (United States)

    Sato, Keiko; Watanabe, Toru; Katsumata, Noriyuki; Sato, Tosiya; Ohashi, Yasuo

    2014-02-01

    Simplified informed consent forms have been successful in improving patient satisfaction and decreasing patient anxiety. However, unsolved problems remain about whether these documents improve comprehension and satisfaction of patients with standard literacy skills. s To investigate whether a detailed consent form explaining the key elements of informed consent, in comparison to a standard consent form, would increase the comprehension and satisfaction of adult cancer patients. Patients who were eligible for the National Surgical Adjuvant Study of Breast Cancer (protocol 01(N-SAS/BC-01)) were randomly selected to receive one of the following four versions: detailed document with graphics, detailed document without graphics, standard document with graphics, and standard document without graphics. The forms were written in plain language from the patients' point of view. A total of 85 patients were administered questionnaires via interview to assess levels of comprehension, satisfaction, and anxiety. Patients demonstrated a strong understanding of information regarding treatment and research. Patient comprehension did not differ significantly between the detailed document arms and the standard document arms. Patient satisfaction level increased according to the amount of information presented in the consent form; most patients preferred the detailed document with graphics. Anxiety and accrual rates in the parent study were not affected by informed consent procedures. Findings were limited to adults who had standard literacy skills and may not be generalizable to a population with lower literacy. Informed consent can be a significant experience for a population with standard literacy skills, as long as the document is easily comprehensible. Such information should be provided in a format that corresponds with patient needs, education levels, and preferences.

  17. Framework programme for detailed characterisation in connection with construction and operation of a final repository for spent nuclear fuel

    Energy Technology Data Exchange (ETDEWEB)

    2010-10-15

    This report presents a programme for the detailed investigations planned to be applied during construction and operation of the repository for spent nuclear fuel at Forsmark. The report is part of SKB's application according to the Nuclear Activities Act. The detailed investigations shall provide relevant data on and site-descriptive models for the bedrock, soil deposits and eco-system of the site in order to facilitate a step-wise design and construction of the final repository. This shall be implemented in a manner that all demands on long-term safety are fulfilled, including accurate documentation of the construction work, and so that assessments of the environmental impact of the repository can be made. For the operational phase, the detailed investigations should also provide support to the deposition process with related decisions, thereby enabling fulfilment of the design premises for the siting and construction of deposition tunnels and deposition holes, as well as for deposition of canisters, and for the subsequent backfilling and closure of the repository. The Observational Method will be applied during the construction of the repository. This method entails establishing in advance acceptable limits of behaviour regarding selected geoscientific parameters and preparing a plan with measures to keep the outcome within these limits. Predictions of expected rock properties are established for each tunnel section. The outcome after excavation is compared with the acceptable range of outcomes. Information from detailed characterization will be of essential importance for application of the Observational Method and for adapting the repository to the prevailing rock properties. SKB has for the past several decades developed methods for site characterisation, applying both above- and underground investigation techniques. Experiences from this work, put into practice during the site investigations, has resulted in a solid knowledge and understanding of the

  18. Featured Image: New Detail in the Toothbrush Cluster

    Science.gov (United States)

    Kohler, Susanna

    2018-01-01

    This spectacular composite (click here for the full image) reveals the galaxy cluster 1RXS J0603.3+4214, known as the Toothbrush cluster due to the shape of its most prominent radio relic. Featured in a recent publication led by Kamlesh Rajpurohit (Thuringian State Observatory, Germany), this image contains new Very Large Array (VLA) 1.5-GHz observations (red) showing the radio emission within the cluster. This is composited with a Chandra view of the X-ray emitting gas of the cluster (blue) and an optical image of the background from Subaru data. The new deep VLA data totaling 26 hours of observations provides a detailed look at the complex structure within the Toothbrush relic, revealing enigmatic filaments and twists (see below). This new data will help us to explore the possible merger history of this cluster, which is theorized to have caused the unusual shapes we see today. For more information, check out the original article linked below.High resolution VLA 12 GHz image of the Toothbrush showing the complex, often filamentary structures. [Rajpurohit et al. 2018]CitationK. Rajpurohit et al 2018 ApJ 852 65. doi:10.3847/1538-4357/aa9f13

  19. Characteristics of physicians targeted by the pharmaceutical industry to participate in e-detailing.

    Science.gov (United States)

    Alkhateeb, Fadi M; Khanfar, Nile M; Doucette, William R; Loudon, David

    2009-01-01

    Electronic detailing (e-detailing) has been introduced in the last few years by the pharmaceutical industry as a new communication channel through which to promote pharmaceutical products to physicians. E-detailing involves using digital technology, such as Internet, video conferencing, and interactive voice response, by which drug companies target their marketing efforts toward specific physicians with pinpoint accuracy. A mail survey of 671 Iowa physicians was used to gather information about the physician characteristics and practice setting characteristics of those who are usually targeted by pharmaceutical companies to participate in e-detailing. A model is developed and tested to explain firms' targeting strategy for targeting physicians for e-detailing.

  20. Simulation of flame-vortex interaction using detailed and reduced

    Energy Technology Data Exchange (ETDEWEB)

    Hilka, M. [Gaz de France (GDF), 75 - Paris (France); Veynante, D. [Ecole Centrale de Paris, Laboratoire EM2C. CNRS, 92 - Chatenay-Malabry (France); Baum, M. [CERFACS (France); Poinsot, T.J. [Centre National de la Recherche Scientifique (CNRS), 45 - Orleans-la-Source (France). Institut de Mecanique des Fluides de Toulouse

    1996-12-31

    The interaction between a pair of counter-rotating vortices and a lean premixed CH{sub 4}/O{sub 2}/N{sub 2} flame ({Phi} = + 0.55) has been studied by direct numerical simulations using detailed and reduced chemical reaction schemes. Results from the complex chemistry simulation are discussed with respect to earlier experiments and differences in the simulations using detailed and reduces chemistry are investigated. Transient evolutions of the flame surface and the total heat release rate are compared and modifications in the evolution of the local flame structure are displayed. (authors) 22 refs.

  1. Diagnostic microbiology in veterinary dermatology: present and future

    DEFF Research Database (Denmark)

    Guardabassi, Luca; Damborg, Peter; Stamm, Ivonne

    2017-01-01

    the identification (ID) and antimicrobial susceptibility testing (AST) of key pathogens in veterinary dermatology. Methods The Study Group for Veterinary Microbiology (ESGVM) of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) identified scientific, technological, educational...... not adequately equipped to run up-to-date clinical microbiologic diagnostic tests. Conclusions and clinical importance ESGVM recommends the use of laboratories employing mass spectrometry for ID and broth micro-dilution for AST, and offering assistance by expert microbiologists on pre- and post-analytical issues......Background The microbiology laboratory can be perceived as a service provider rather than an integral part of the healthcare team. Objectives The aim of this review is to discuss the current challenges of providing a state-of-the-art diagnostic veterinary microbiology service including...

  2. Detailed Structural Analysis of Critical Wendelstein 7-X Magnet System Components

    International Nuclear Information System (INIS)

    Egorov, K.

    2006-01-01

    The Wendelstein 7-X (W7-X) stellarator experiment is presently under construction and assembly in Greifswald, Germany. The goal of the experiment is to verify that the stellarator magnetic confinement concept is a viable option for a fusion reactor. The complex W7-X magnet system requires a multi-level approach to structural analysis for which two types of finite element models are used: Firstly, global models having reasonably coarse meshes with a number of simplifications and assumptions, and secondly, local models with detailed meshes of critical regions and elements. Widely known sub-modelling technique with boundary conditions extracted from the global models is one of the approaches for local analysis with high assessment efficiency. In particular, the winding pack (WP) of the magnet coils is simulated in the global model as a homogeneous orthotropic material with effective mechanical characteristic representing its real composite structure. This assumption allows assessing the whole magnet system in terms of general structural factors like forces and moments on the support elements, displacements of the main components, deformation and stress in the coil casings, etc. In a second step local models with a detailed description of more critical WP zones are considered in order to analyze their internal components like conductor jackets, turn insulation, etc. This paper provides an overview of local analyses of several critical W7-X magnet system components with particular attention on the coil winding packs. (author)

  3. 9RU2 Radiological protection, attention to the detail-EPU

    International Nuclear Information System (INIS)

    Padilla C, I.

    2008-01-01

    To optimize times and movements in a reload project of nuclear fuel in a nuclear plant, where they are programmed more three thousand maintenance activities, modifications, monitoring and inspection in a smaller period to 30 days, and additionally to optimize the individual and collective dose in the same one, turn out to be important challenges where the used strategies must be accompanied of a deep knowledge of the installation in the radiological sense and of the spaces conceptualized in the time. The attention to the detail makes possible that the objectives are fulfilled. During the shutdown of reload 9 of Unit 2 (9RU2) of the nuclear power plant of Laguna Verde, the attention in detail applied in the critical points allowed a saving of dose of 0.7 Sv-person and one deviation of the goal of only +0.85% (smaller to 1% of the goal established like 2 challenge of Sv-person). Analysis of times, movements and training to develop skills in inspection activities in service that requires intervention in the external surface of the reactor vessel to examine the condition of welds, allowed reducing times of execution of 12 to 2 hours. Analysis of the environment and attention to the detail are techniques that allowed optimizing dose in 9RU2 and they were used in the project Power Increase. In this work the strategies of the surroundings and attention in detail applied in 9RU2 would appear and detail attention in the increase of power in the reload 13 Unit 1. (Author)

  4. Forgotten antibiotics: an inventory in Europe, the United States, Canada, and Australia.

    NARCIS (Netherlands)

    Pulcini, C.; Bush, K.; Craig, W.A.; Frimodt-Moller, N.; Grayson, M.L.; Mouton, J.W.; Turnidge, J.; Harbarth, S.; Gyssens, I.C.J.

    2012-01-01

    In view of the alarming spread of antimicrobial resistance in the absence of new antibiotics, this study aimed at assessing the availability of potentially useful older antibiotics. A survey was performed in 38 countries among experts including hospital pharmacists, microbiologists, and infectious

  5. Forgotten antibiotics

    DEFF Research Database (Denmark)

    Pulcini, Céline; Bush, Karen; Craig, William A

    2012-01-01

    In view of the alarming spread of antimicrobial resistance in the absence of new antibiotics, this study aimed at assessing the availability of potentially useful older antibiotics. A survey was performed in 38 countries among experts including hospital pharmacists, microbiologists, and infectious...

  6. New tools for comparing microscopy images : Quantitative analysis of cell types in Bacillus subtilis

    NARCIS (Netherlands)

    van Gestel, Jordi; Vlamakis, Hera; Kolter, Roberto

    2015-01-01

    Fluorescence microscopy is a method commonly used to examine individual differences between bacterial cells, yet many studies still lack a quantitative analysis of fluorescence microscopy data. Here we introduce some simple tools that microbiologists can use to analyze and compare their microscopy

  7. Interactive 3D audio: Enhancing awareness of details in immersive soundscapes?

    DEFF Research Database (Denmark)

    Schmidt, Mikkel Nørgaard; Schwartz, Stephen; Larsen, Jan

    2012-01-01

    Spatial audio and the possibility of interacting with the audio environment is thought to increase listeners' attention to details in a soundscape. This work examines if interactive 3D audio enhances listeners' ability to recall details in a soundscape. Nine different soundscapes were constructed...

  8. Detailed services in a spatial data infrastructure from the computation viewpoint

    CSIR Research Space (South Africa)

    Cooper, Antony K

    2009-11-01

    Full Text Available the detailed services that are performed within each of these components, and the roles played by these components in the different phases of establishing and using an SDI. The matrix of these detailed services is too large for inclusion in this conference...

  9. Health care providers: a missing link in understanding acceptability of the female condom.

    Science.gov (United States)

    Mantell, Joanne E; West, Brooke S; Sue, Kimberly; Hoffman, Susie; Exner, Theresa M; Kelvin, Elizabeth; Stein, Zena A

    2011-02-01

    Health care providers can play a key role in influencing clients to initiate and maintain use of the female condom, an underused method for HIV/STI and pregnancy prevention. In 2001-2002, based on semistructured interviews with 78 health care providers from four types of settings in New York City, we found that most providers had seen the female condom, but they had not used it and did not propose the method to clients. They lacked details about the method-when to insert it, where it can be obtained, and its cost. Gender of provider, provider level of training, and setting appeared to influence their attitudes. Unless and until provider training on the female condom is greatly improved, broader acceptance of this significant public health contribution to preventing HIV/AIDS and unwanted pregnancy will not be achieved.

  10. Cybercom Chief Details U.S. Cyber Threats

    Science.gov (United States)

    Security Robots Lasers RSS Feed Cybercom Chief Details U.S. Cyber Threats - December 2, 2014 Navy Adm . Rogers, the commander of U.S. Cyber Command, director of the National Security Agency and chief of the Framework for Cyber Sharing But before Cybercom can help commercial companies deal with cyber criminals and

  11. Detailed 3-D nuclear analysis of ITER outboard blanket modules

    Energy Technology Data Exchange (ETDEWEB)

    Bohm, Tim, E-mail: tdbohm@wisc.edu [Fusion Technology Institute, University of Wisconsin-Madison, Madison, WI (United States); Davis, Andrew; Sawan, Mohamed; Marriott, Edward; Wilson, Paul [Fusion Technology Institute, University of Wisconsin-Madison, Madison, WI (United States); Ulrickson, Michael; Bullock, James [Formerly, Fusion Technology, Sandia National Laboratories, Albuquerque, NM (United States)

    2015-10-15

    Highlights: • Nuclear analysis was performed on detailed CAD models placed in a 40 degree model of ITER. • The regions examined include BM09, the upper ELM coil region (BM11–13), the neutral beam (NB) region (BM13–16), and BM18. • The results show that VV nuclear heating exceeds limits in the NB and upper ELM coil regions. • The results also show that the level of He production in parts of BM18 exceeds limits. • These calculations are being used to modify the design of the ITER blanket modules. - Abstract: In the ITER design, the blanket modules (BM) provide thermal and nuclear shielding for the vacuum vessel (VV), magnets, and other components. We used the CAD based DAG-MCNP5 transport code to analyze detailed models inserted into a 40 degree partially homogenized ITER global model. The regions analyzed include BM09, BM16 near the heating neutral beam injection (HNB) region, BM11–13 near the upper ELM coil region, and BM18. For the BM16 HNB region, the VV nuclear heating behind the NB region exceeds the design limit by up to 80%. For the BM11–13 region, the nuclear heating of the VV exceeds the design limit by up to 45%. For BM18, the results show that He production does not meet the limit necessary for re-welding. The results presented in this work are being used by the ITER Organization Blanket and Tokamak Integration groups to modify the BM design in the cases where limits are exceeded.

  12. Detailed 3-D nuclear analysis of ITER outboard blanket modules

    International Nuclear Information System (INIS)

    Bohm, Tim; Davis, Andrew; Sawan, Mohamed; Marriott, Edward; Wilson, Paul; Ulrickson, Michael; Bullock, James

    2015-01-01

    Highlights: • Nuclear analysis was performed on detailed CAD models placed in a 40 degree model of ITER. • The regions examined include BM09, the upper ELM coil region (BM11–13), the neutral beam (NB) region (BM13–16), and BM18. • The results show that VV nuclear heating exceeds limits in the NB and upper ELM coil regions. • The results also show that the level of He production in parts of BM18 exceeds limits. • These calculations are being used to modify the design of the ITER blanket modules. - Abstract: In the ITER design, the blanket modules (BM) provide thermal and nuclear shielding for the vacuum vessel (VV), magnets, and other components. We used the CAD based DAG-MCNP5 transport code to analyze detailed models inserted into a 40 degree partially homogenized ITER global model. The regions analyzed include BM09, BM16 near the heating neutral beam injection (HNB) region, BM11–13 near the upper ELM coil region, and BM18. For the BM16 HNB region, the VV nuclear heating behind the NB region exceeds the design limit by up to 80%. For the BM11–13 region, the nuclear heating of the VV exceeds the design limit by up to 45%. For BM18, the results show that He production does not meet the limit necessary for re-welding. The results presented in this work are being used by the ITER Organization Blanket and Tokamak Integration groups to modify the BM design in the cases where limits are exceeded.

  13. Accumulating and remembering the details of neutral and emotional natural scenes.

    Science.gov (United States)

    Melcher, David

    2010-01-01

    In contrast to our rich sensory experience with complex scenes in everyday life, the capacity of visual working memory is thought to be quite limited. Here our memory has been examined for the details of naturalistic scenes as a function of display duration, emotional valence of the scene, and delay before test. Individual differences in working memory and long-term memory for pictorial scenes were examined in experiment 1. The accumulation of memory for emotional scenes and the retention of these details in long-term memory were investigated in experiment 2. Although there were large individual differences in performance, memory for scene details generally exceeded the traditional working memory limit within a few seconds. Information about positive scenes was learned most quickly, while negative scenes showed the worst memory for details. The overall pattern of results was consistent with the idea that both short-term and long-term representations are mixed together in a medium-term 'online' memory for scenes.

  14. Customer assessment of long-term care pharmacy provider services.

    Science.gov (United States)

    Clark, Thomas R

    2008-09-01

    Assess performance of long-term care pharmacy providers on key services offered to nursing facilities. Cross-sectional; nursing facility team. Random phone survey of nursing facility team members. 485 nursing facility team members (practicing in nursing facilities, interacting with > or = 1 consultant pharmacist); 46 members excluded, unable to identify facility's pharmacy provider. Directors of nursing, medical directors, and administrators were asked to rate long-term care pharmacy provider performance of eight commonly offered pharmacy services. All groups evaluated pharmacy provider performance of these services using a five-point scale. Results are broken down by employer type. Average rating for eight pharmacy services was 3.64. Top two services: "Labeling medications accurately" ranked in top 1-2 services for all groups (combined rating of 3.97) and "Provides medication administration system" ranked in top 1-3 services for all groups (combined rating of 3.95). One service, "Provides educational inservices," ranked lowest for all groups (combined rating of 3.54). In general, when looking at the eight services in combination for all providers, all services were ranked between Good and Very Good (average score of 3.64). Therefore, while the pharmacy provider is performing above average for these services, there is room for improvement in all of these services. These results can be used as a benchmark. Detailed data results and sample surveys are available online at www.ascp.com/supplements. These surveys can be used by the pharmacy provider to solicit assessments from their own facilities on these services.

  15. Detailed model for practical pulverized coal furnaces and gasifiers

    Energy Technology Data Exchange (ETDEWEB)

    Philips, S.D.; Smoot, L.D.

    1989-08-01

    The need to improve efficiency and reduce pollutant emissions commercial furnaces has prompted energy companies to search for optimized operating conditions and improved designs in their fossil-fuel burning facilities. Historically, companies have relied on the use of empirical correlations and pilot-plant data to make decisions about operating conditions and design changes. The high cost of collecting data makes obtaining large amounts of data infeasible. The main objective of the data book is to provide a single source of detailed three-dimensional combustion and combustion-related data suitable for comprehensive combustion model evaluation. Five tasks were identified as requirements to achieve the main objective. First, identify the types of data needed to evaluate comprehensive combustion models, and establish criteria for selecting the data. Second, identify and document available three-dimensional combustion data related to pulverized coal combustion. Third, collect and evaluate three-dimensional data cases, and select suitable cases based on selection criteria. Fourth, organize the data sets into an easy-to-use format. Fifth, evaluate and interpret the nature and quality of the data base. 39 refs., 15 figs., 14 tabs.

  16. Optical versus radiographic magnification for fine-detail skeletal radiography

    International Nuclear Information System (INIS)

    Genant, H.K.; Doi, K.; Mall, J.C.

    1974-01-01

    Fine detail radiographic techniques for peripheral skeletal imaging have gained wide clinical acceptance. In this study, the imaging properties and clinical applications of the optical magnification technique, which employs fine-grain industrial film and a large focal spot, have been compared quantitatively and qualitatively with those of three slow screen-film techniques, namely, contact exposure with a large focal spot, 2X radiographic magnification with a 0.3 mm focal spot, and 4X radiographic magnification with a 50 μ focal spot. The modulation transfer functions (MTFs) of the recording systems and focal spots have been obtained and film sensitometry has been performed. Clinical comparisons for patients with metabolic, arthritic, and neoplastic skeletal disorders have been made. The results illustrate the superiority of the optical magnification technique over contact or 2X magnification techniques using slow screen-film systems. If a microfocus tube is used, however, direct radiographic magnification may provide images comparable in resolution, noise, and contrast to those made with the optical magnification technique, and at lower radiation exposure to the patient. (U.S.)

  17. Revisiting the concept level of detail in 3D city modelling

    NARCIS (Netherlands)

    Biljecki, F.; Zhao, J.; Stoter, J.E.; Ledoux, H.

    2013-01-01

    This review paper discusses the concept of level of detail in 3D city modelling, and is a first step towards a foundation for a standardised definition. As an introduction, a few level of detail specifications, outlooks and approaches are given from the industry. The paper analyses the general

  18. Moderating the Seductive Details Effect in Multimedia Learning with Note-Taking

    Science.gov (United States)

    Wang, Zhe; Sundararajan, Narayankripa; Adesope, Olusola O.; Ardasheva, Yuliya

    2017-01-01

    Although the seductive details effect, a phenomenon where interesting but irrelevant pictures impede comprehension, is well documented, studies examining ways of moderating its detrimental impact on learning remain few. The present study examined the effect of note-taking on the seductive details effect. Chinese undergraduate participants (N = 91)…

  19. ADVANCING THE PROCESSING TECHNOLOGIES OF THE DETAILS OF CONSTRUCTION MACHINERY AND EQUIPMENT

    Directory of Open Access Journals (Sweden)

    Burlachenko Oleg Vasil’evich

    2016-03-01

    Full Text Available On the contemporary stage on the development and advancement of processing technologies of machine and equipment details it is necessary to find a complex solution to the problem of their performance characteristics. This solution supposes the development of specific methods providing and advancing some specific index of performance efficiency (often regardless of real coupling state and the creation and implementation of the technologies having complex physical and technical impacts on the contact combination. The novelty of processing methods is determined by all the components of the technological system, each of which has its own novelty or creates the novelty of the system as a whole due to definite non-traditional combination of the known components. The system of improving the existing and creating new methods and technological processes of manufacturing the products is considered. The mechanical, physical and chemical effects on the work surface in case of specific kinematics of tool path and the workpieces during operation, and also the wear of engine cylinders are analyzed. The authors offer a technology of obtaining nonporous hot-stamped powder alloys with higher strength properties of the outer surface and high plastic properties of core. The unity of the processes of power, temperature and other effects on the working surface of details during their manufacture and operation is established.

  20. When to ask male adolescents to provide semen sample for fertility preservation?

    OpenAIRE

    Dabaja, Ali A.; Wosnitzer, Matthew S.; Bolyakov, Alexander; Schlegel, Peter N.; Paduch, Darius A.

    2014-01-01

    Background Fertility preservation in adolescents undergoing sterilizing radiation and/or chemotherapy is the standard of care in oncology. The opportunity for patients to provide a semen sample by ejaculation is a critical issue in adolescent fertility preservation. Methods Fifty males with no medical or sexual developmental abnormalities were evaluated. The subjects were screened for evidence of orgasmic, erectile, and ejaculatory dysfunction. A detailed sexual development history was obtain...

  1. CDC WONDER: Detailed Mortality - Underlying Cause of Death

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Detailed Mortality - Underlying Cause of Death data on CDC WONDER are county-level national mortality and population data spanning the years 1999-2009. Data are...

  2. End region detailing of pretensioned concrete bridge girders.

    Science.gov (United States)

    2013-03-01

    End region detailing has significant effect on the serviceability, behavior, and capacity of pretensioned concrete girders. : In this project, experimental and analytical research programs were conducted to evaluate and quantify the effects of : diff...

  3. What is adaptation by natural selection? Perspectives of an experimental microbiologist.

    Science.gov (United States)

    Lenski, Richard E

    2017-04-01

    Ever since Darwin, the role of natural selection in shaping the morphological, physiological, and behavioral adaptations of animals and plants across generations has been central to understanding life and its diversity. New discoveries have shown with increasing precision how genetic, molecular, and biochemical processes produce and express those organismal features during an individual's lifetime. When it comes to microorganisms, however, understanding the role of natural selection in producing adaptive solutions has historically been, and sometimes continues to be, contentious. This tension is curious because microbes enable one to observe the power of adaptation by natural selection with exceptional rigor and clarity, as exemplified by the burgeoning field of experimental microbial evolution. I trace the development of this field, describe an experiment with Escherichia coli that has been running for almost 30 years, and highlight other experiments in which natural selection has led to interesting dynamics and adaptive changes in microbial populations.

  4. The Turn the Tables Technique (T[cube]): A Program Activity to Provide Group Facilitators Insight into Teen Sexual Behaviors and Beliefs

    Science.gov (United States)

    Sclafane, Jamie Heather; Merves, Marni Loiacono; Rivera, Angelic; Long, Laura; Wilson, Ken; Bauman, Laurie J.

    2012-01-01

    The Turn the Tables Technique (T[cube]) is an activity designed to provide group facilitators who lead HIV/STI prevention and sexual health promotion programs with detailed and current information on teenagers' sexual behaviors and beliefs. This information can be used throughout a program to tailor content. Included is a detailed lesson plan of…

  5. Detailed field test of yaw-based wake steering

    DEFF Research Database (Denmark)

    Fleming, P.; Churchfield, M.; Scholbrock, A.

    2016-01-01

    production. In the first phase, a nacelle-mounted scanning lidar was used to verify wake deflection of a misaligned turbine and calibrate wake deflection models. In the second phase, these models were used within a yaw controller to achieve a desired wake deflection. This paper details the experimental......This paper describes a detailed field-test campaign to investigate yaw-based wake steering. In yaw-based wake steering, an upstream turbine intentionally misaligns its yaw with respect to the inflow to deflect its wake away from a downstream turbine, with the goal of increasing total power...... design and setup. All data collected as part of this field experiment will be archived and made available to the public via the U.S. Department of Energy’s Atmosphere to Electrons Data Archive and Portal....

  6. Increased accuracy in mineral and hydrogeophysical modelling of HTEM data via detailed description of system transfer function and constrained inversion

    DEFF Research Database (Denmark)

    Viezzoli, Andrea; Christiansen, Anders Vest; Auken, Esben

    This paper aims at providing more insight into the parameters that need to be modelled during inversion of Helicopter TEM data for accurate modelling, both for hydrogeophysical and exploration applications. We use synthetic data to show in details the effect, both in data and in model space...

  7. Detailed Sensory Memory, Sloppy Working Memory

    OpenAIRE

    Sligte, Ilja G.; Vandenbroucke, Annelinde R. E.; Scholte, H. Steven; Lamme, Victor A. F.

    2010-01-01

    Visual short-term memory (VSTM) enables us to actively maintain information in mind for a brief period of time after stimulus disappearance. According to recent studies, VSTM consists of three stages - iconic memory, fragile VSTM, and visual working memory - with increasingly stricter capacity limits and progressively longer lifetimes. Still, the resolution (or amount of visual detail) of each VSTM stage has remained unexplored and we test this in the present study. We presented people with a...

  8. Plant-microbe and plant-insect interactions meet common grounds

    NARCIS (Netherlands)

    Schenk, P.; McGrath, K.C.; Lorito, M.; Pieterse, C.M.J.

    2008-01-01

    Plant–microbe and plant–insect interactions are of global importance for agriculture and of high interest to many plant scientists, microbiologists and entomologists. Traditionally, plant–microbe and plant–insect interactions have been looked at as two separate issues, but in recent years it has

  9. MEMS and the microbe

    NARCIS (Netherlands)

    Ingham, C.J.; Vlieg, J.E.T.V.H.

    2008-01-01

    In recent years, relatively simple MEMS fabrications have helped accelerate our knowledge of the microbial cell. Current progress and challenges in the application of lab-on-a-chip devices to the viable microbe are reviewed. Furthermore, the degree to which microbiologists are becoming the engineers

  10. Human Factors Considerations in New Nuclear Power Plants: Detailed Analysis.

    Energy Technology Data Exchange (ETDEWEB)

    OHara,J.; Higgins, J.; Brown, W.; Fink, R.

    2008-02-14

    This Nuclear Regulatory Commission (NRC) sponsored study has identified human-performance issues in new and advanced nuclear power plants. To identify the issues, current industry developments and trends were evaluated in the areas of reactor technology, instrumentation and control technology, human-system integration technology, and human factors engineering (HFE) methods and tools. The issues were organized into seven high-level HFE topic areas: Role of Personnel and Automation, Staffing and Training, Normal Operations Management, Disturbance and Emergency Management, Maintenance and Change Management, Plant Design and Construction, and HFE Methods and Tools. The issues where then prioritized into four categories using a 'Phenomena Identification and Ranking Table' methodology based on evaluations provided by 14 independent subject matter experts. The subject matter experts were knowledgeable in a variety of disciplines. Vendors, utilities, research organizations and regulators all participated. Twenty issues were categorized into the top priority category. This Brookhaven National Laboratory (BNL) technical report provides the detailed methodology, issue analysis, and results. A summary of the results of this study can be found in NUREG/CR-6947. The research performed for this project has identified a large number of human-performance issues for new control stations and new nuclear power plant designs. The information gathered in this project can serve as input to the development of a long-term strategy and plan for addressing human performance in these areas through regulatory research. Addressing human-performance issues will provide the technical basis from which regulatory review guidance can be developed to meet these challenges. The availability of this review guidance will help set clear expectations for how the NRC staff will evaluate new designs, reduce regulatory uncertainty, and provide a well-defined path to new nuclear power plant

  11. Quality system target on a detail design activity irradiator ISG 500

    International Nuclear Information System (INIS)

    Reinhard Pardede

    2010-01-01

    Currently, an engineering team of Nuclear Equipment Engineering Center PRPN has been beening technology innovation detail design of Irradiator ISG 500, then enter continuing to a construction phase. A schedule detail design still being not finish yet. The installation of Irradiator ISG 500 will be used to preservative the result of agricultural product in Indonesia. It is known as an export commodity and row material for food. However, its quality need some improvements in order to meet internal and foreign consumer standard. To enhance a quality system in detail design phase has already used ISO 9001: 2008 on clausul-7: Product Realization-design. It also needs a radioactive regulation Bapeten-Indonesian Nuclear Energy Surveillance Agency compliance with IAEA GS-R 3: 2006 as well. Scope of activity design is Instrumentation and Control system; Mechanical- Electrical; Radiation and Safety and Dosimetry; Civil Structured; Quality Assurance and Technoeconomic. Technology Innovating be applied to achieved economics through Costumer and Market Focused. Gamma irradiation of Irradiator ISG 500 can be used to improve hygienic quality in terms of technological as well as economical aspects. Technology innovation fit with the state of the arts right now. Assessment should be done base not only internal audit but also monitoring and surveillance as well. By application of a Quality System on detail design activity hopefully to enhance quality on detail design, construction, more over irradiator operation. (author)

  12. Talent in autism: hyper-systemizing, hyper-attention to detail and sensory hypersensitivity.

    Science.gov (United States)

    Baron-Cohen, Simon; Ashwin, Emma; Ashwin, Chris; Tavassoli, Teresa; Chakrabarti, Bhismadev

    2009-05-27

    We argue that hyper-systemizing predisposes individuals to show talent, and review evidence that hyper-systemizing is part of the cognitive style of people with autism spectrum conditions (ASC). We then clarify the hyper-systemizing theory, contrasting it to the weak central coherence (WCC) and executive dysfunction (ED) theories. The ED theory has difficulty explaining the existence of talent in ASC. While both hyper-systemizing and WCC theories postulate excellent attention to detail, by itself excellent attention to detail will not produce talent. By contrast, the hyper-systemizing theory argues that the excellent attention to detail is directed towards detecting 'if p, then q' rules (or [input-operation-output] reasoning). Such law-based pattern recognition systems can produce talent in systemizable domains. Finally, we argue that the excellent attention to detail in ASC is itself a consequence of sensory hypersensitivity. We review an experiment from our laboratory demonstrating sensory hypersensitivity detection thresholds in vision. We conclude that the origins of the association between autism and talent begin at the sensory level, include excellent attention to detail and end with hyper-systemizing.

  13. Interactive tele-education applied to a distant clinical microbiology specialization university course.

    Science.gov (United States)

    Andreazzi, Denise B; Rossi, Flávia; Wen, Chao L

    2011-09-01

    The microbiology laboratory provides a strategic support for infectious disease diagnosis and also alerts the medical community about bacterial resistance to antibiotics. The microbiologists' training is a challenge in Brazil, a country with an extensive territory, a diverse population, and disparity of resource allocation. The aim of this study was to implement an interactive tele-educational course in clinical microbiology to reach distant laboratory workers and to improve their professional skills. The course scientific content was defined according to competences associated, distributed in 560 h, with laboratory practices (knowledge matrix-contextual education). The 11-module course structure comprised 70% distance learning, 22% on campus (integrated modules), and 8% monographs. The group included 7 physicians and 21 microbiologists from 20 different Brazilian cities. The time flexibility and location were the two main reasons for student participation, thus decreasing absences to the workplace, different from the traditional teaching methodologies. The group performance was measured by monthly evaluations, and 1 year postcourse, the researcher visited their workplace. There was significant improvement in microbiological practices performed before compared with after group participation. Therefore, 76.9% of laboratory practices were modified because of the knowledge acquired in the course. Students showed behavioral changes in relation to performance in infection control as well as on the dissemination of their knowledge. This specialization course using distance education did not compromise the quality. This educational methodology represents an alternative to teach clinical microbiology to laboratory workers from remote hospitals, as a nationwide continuing educational strategy.

  14. SCOWLP: a web-based database for detailed characterization and visualization of protein interfaces

    Directory of Open Access Journals (Sweden)

    Schroeder Michael

    2006-03-01

    substantially the description of protein interfaces by adding detailed interface information of peptidic-ligands and solvent to the existing protein-protein interaction databases. SCOWLP may be of interest to many structural bioinformaticians. It provides a platform for automatic global mapping of protein interfaces at atomic level, representing a useful tool for classification of protein interfaces, protein binding comparative studies, reconstruction of protein complexes and understanding protein networks. The web-server with the database and its additional summary tables used for our analysis are available at http://www.scowlp.org.

  15. Detailed leak detection test plan and schedule for the Oak Ridge National Laboratory LLLW active tanks

    International Nuclear Information System (INIS)

    Douglas, D.G.; Maresca, J.W. Jr.

    1993-03-01

    This document provides a detailed leak detection test plan and schedule for leak testing many of the tanks that comprise the active portion of the liquid low-level waste (LLLW) system at the Oak Ridge National Laboratory (ORNL). This plan was prepared in response to the requirements of the Federal Facility Agreement (FFA) between the US Department of Energy (DOE) and two other agencies, the US Environmental Protection Agency (EPA) and the Tennessee Department of Environment and Conservation (TDEC)

  16. Terry Turbopump Expanded Operating Band Full-Scale Component and Basic Science Detailed Test Plan-Revision 2

    Energy Technology Data Exchange (ETDEWEB)

    Solom, Matthew [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Severe Accident Analysis Dept.; Ross, Kyle [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Severe Accident Analysis Dept.; Cardoni, Jeffrey N. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Severe Accident Analysis Dept.; Osborn, Douglas [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Severe Accident Analysis Dept.

    2017-08-01

    This document details the milestone approach to define the true operating limitations (margins) of the Terry turbopump systems used in the nuclear industry for Milestone 3 (full-scale component experiments) and Milestone 4 (Terry turbopump basic science experiments) efforts. The overall multinational-sponsored program creates the technical basis to: (1) reduce and defer additional utility costs, (2) simplify plant operations, and (3) provide a better understanding of the true margin which could reduce overall risk of operations.

  17. Acceleration of Convergence to Equilibrium in Markov Chains by Breaking Detailed Balance

    Science.gov (United States)

    Kaiser, Marcus; Jack, Robert L.; Zimmer, Johannes

    2017-07-01

    We analyse and interpret the effects of breaking detailed balance on the convergence to equilibrium of conservative interacting particle systems and their hydrodynamic scaling limits. For finite systems of interacting particles, we review existing results showing that irreversible processes converge faster to their steady state than reversible ones. We show how this behaviour appears in the hydrodynamic limit of such processes, as described by macroscopic fluctuation theory, and we provide a quantitative expression for the acceleration of convergence in this setting. We give a geometrical interpretation of this acceleration, in terms of currents that are antisymmetric under time-reversal and orthogonal to the free energy gradient, which act to drive the system away from states where (reversible) gradient-descent dynamics result in slow convergence to equilibrium.

  18. New details emerge from the Einstein files

    CERN Multimedia

    Overbye, D

    2002-01-01

    For many years the FBI spied on Einstein. New details of this surveilance are emerging in "The Einstein File: J. Edgar Hoover's Secret War Against the World's Most Famous Scientist," by Fred Jerome, who sued the government with the help of the Public Citizen Litigation Group to obtain a less censored version of the file (1 page).

  19. Verifying detailed fluctuation relations for discrete feedback-controlled quantum dynamics

    Science.gov (United States)

    Camati, Patrice A.; Serra, Roberto M.

    2018-04-01

    Discrete quantum feedback control consists of a managed dynamics according to the information acquired by a previous measurement. Energy fluctuations along such dynamics satisfy generalized fluctuation relations, which are useful tools to study the thermodynamics of systems far away from equilibrium. Due to the practical challenge to assess energy fluctuations in the quantum scenario, the experimental verification of detailed fluctuation relations in the presence of feedback control remains elusive. We present a feasible method to experimentally verify detailed fluctuation relations for discrete feedback control quantum dynamics. Two detailed fluctuation relations are developed and employed. The method is based on a quantum interferometric strategy that allows the verification of fluctuation relations in the presence of feedback control. An analytical example to illustrate the applicability of the method is discussed. The comprehensive technique introduced here can be experimentally implemented at a microscale with the current technology in a variety of experimental platforms.

  20. Some technical details concerning a new method of gravimetric-seismic inversion

    DEFF Research Database (Denmark)

    Strykowski, Gabriel

    1999-01-01

    In this paper a number of technical details related to a new method of gravimetric-seismic inversion, which is still under development, are explained. Although the present contribution aims on providing general statements on how to formulate and solve complex gravimetric-seismic modeling; problems......, the inspiration comes from the practical modeling problems in the area of Jutland peninsula (Denmark). More specifically, the methodological aspects of the proposed inversion method are illustrated on a problem of 3D modeling of the intra crustal intrusion associated with the Silkeborg Gravity High. The existing...... refraction seismic profile locates the source of the anomaly in depths 10 km - 18 km. In an earlier publication, (Strykowski, 1998), and for the same test area, a method of complex geological stripping is described. The present contribution is a continuation of this paper in the direction of inversion...

  1. Implementation of a next-generation electronic nursing records system based on detailed clinical models and integration of clinical practice guidelines.

    Science.gov (United States)

    Min, Yul Ha; Park, Hyeoun-Ae; Chung, Eunja; Lee, Hyunsook

    2013-12-01

    The purpose of this paper is to describe the components of a next-generation electronic nursing records system ensuring full semantic interoperability and integrating evidence into the nursing records system. A next-generation electronic nursing records system based on detailed clinical models and clinical practice guidelines was developed at Seoul National University Bundang Hospital in 2013. This system has two components, a terminology server and a nursing documentation system. The terminology server manages nursing narratives generated from entity-attribute-value triplets of detailed clinical models using a natural language generation system. The nursing documentation system provides nurses with a set of nursing narratives arranged around the recommendations extracted from clinical practice guidelines. An electronic nursing records system based on detailed clinical models and clinical practice guidelines was successfully implemented in a hospital in Korea. The next-generation electronic nursing records system can support nursing practice and nursing documentation, which in turn will improve data quality.

  2. Detailed Performance of the Outer Tracker at LHCb

    CERN Document Server

    Tuning, N

    2014-01-01

    The LHCb Outer Tracker is a gaseous detector covering an area of 5x6m2 with 12 double layers of straw tubes. Based on data of the first LHC running period from 2010 to 2012, the performance in terms of the single hit resolution and efficiency are presented. Details on the ionization length and subtle effects regarding signal reflections and the subsequent time-walk correction are given. The efficiency to detect a hit in the central half of the straw is estimated to be 99.2%, and the position resolution is determined to be approximately 200 um, depending on the detailed implementation of the internal alignment of individual detector modules. The Outer Tracker received a dose in the hottest region corresponding to 0.12 C/cm, and no signs of gain deterioration or other ageing effects are observed.

  3. Organic preservation of fossil musculature with ultracellular detail.

    Science.gov (United States)

    McNamara, Maria; Orr, Patrick J; Kearns, Stuart L; Alcalá, Luis; Anadón, Pere; Peñalver-Mollá, Enrique

    2010-02-07

    The very labile (decay-prone), non-biomineralized, tissues of organisms are rarely fossilized. Occurrences thereof are invaluable supplements to a body fossil record dominated by biomineralized tissues, which alone are extremely unrepresentative of diversity in modern and ancient ecosystems. Fossil examples of extremely labile tissues (e.g. muscle) that exhibit a high degree of morphological fidelity are almost invariably replicated by inorganic compounds such as calcium phosphate. There is no consensus as to whether such tissues can be preserved with similar morphological fidelity as organic remains, except when enclosed inside amber. Here, we report fossilized musculature from an approximately 18 Myr old salamander from lacustrine sediments of Ribesalbes, Spain. The muscle is preserved organically, in three dimensions, and with the highest fidelity of morphological preservation yet documented from the fossil record. Preserved ultrastructural details include myofilaments, endomysium, layering within the sarcolemma, and endomysial circulatory vessels infilled with blood. Slight differences between the fossil tissues and their counterparts in extant amphibians reflect limited degradation during fossilization. Our results provide unequivocal evidence that high-fidelity organic preservation of extremely labile tissues is not only feasible, but likely to be common. This is supported by the discovery of similarly preserved tissues in the Eocene Grube Messel biota.

  4. Improving GRADE evidence tables part 3: detailed guidance for explanatory footnotes supports creating and understanding GRADE certainty in the evidence judgments

    NARCIS (Netherlands)

    Santesso, Nancy; Carrasco-Labra, Alonso; Langendam, Miranda; Brignardello-Petersen, Romina; Mustafa, Reem A.; Heus, Pauline; Lasserson, Toby; Opiyo, Newton; Kunnamo, Ilkka; Sinclair, David; Garner, Paul; Treweek, Shaun; Tovey, David; Akl, Elie A.; Tugwell, Peter; Brozek, Jan L.; Guyatt, Gordon; Schünemann, Holger J.

    2016-01-01

    The Grading of Recommendations Assessment, Development and Evaluation (GRADE) is widely used and reliable and accurate for assessing the certainty in the body of health evidence. The GRADE working group has provided detailed guidance for assessing the certainty in the body of evidence in systematic

  5. Improving GRADE evidence tables part 3 : Detailed guidance for explanatory footnotes supports creating and understanding GRADE certainty in the evidence judgments

    NARCIS (Netherlands)

    Santesso, Nancy; Carrasco-Labra, Alonso; Langendam, Miranda; Brignardello-Petersen, Romina; Mustafa, Reem A.; Heus, Pauline; Lasserson, Toby; Opiyo, Newton; Kunnamo, Ilkka; Sinclair, David; Garner, Paul; Treweek, Shaun; Tovey, David; Akl, Elie A.; Tugwell, Peter; Brozek, Jan L.; Guyatt, Gordon; Schünemann, Holger J.

    Background The Grading of Recommendations Assessment, Development and Evaluation (GRADE) is widely used and reliable and accurate for assessing the certainty in the body of health evidence. The GRADE working group has provided detailed guidance for assessing the certainty in the body of evidence in

  6. Detailed description of an SSAC at the facility level for mixed oxide fuel fabrication facilities

    International Nuclear Information System (INIS)

    Jones, R.J.

    1985-09-01

    The purpose of this document is to provide a detailed description of a system for the accounting for and control of nuclear material in a mixed oxide fuel fabrication facility which can be used by a facility operator to establish his own system to comply with a national system for nuclear material accounting and control and to facilitate application of IAEA safeguards. The scope of this document is limited to descriptions of the following SSAC elements: (1) Nuclear Material Measurements; (2) Measurement Quality; (3) Records and Reports; (4) Physical Inventory Taking; (5) Material Balance Closing

  7. Detailed bathymetric surveys in the central Indian Basin

    Digital Repository Service at National Institute of Oceanography (India)

    Kodagali, V.N.; KameshRaju, K.A.; Ramprasad, T.; George, P.; Jaisankar, S.

    Over 420,000 line kilometers of echo-sounding data was collected in the Central Indian Basin. This data was digitized, merged with navigation data and a detailed bathymetric map of the Basin was prepared. The Basin can be broadly classified...

  8. Worldwide Emerging Environmental Issues Affecting the U.S. Military. September 2008 Report

    Science.gov (United States)

    2008-09-01

    Techniques 8.1.1 Fluorescent Sensor Bacteria Offer Fast Pollutant Detection Jan Van der Meer, an environmental microbiologist at the University of Lausanne...Lebanon Compensations for War Damages The Lebanese newspaper Al- Akhbar reported that UN Secretary-General Ban Ki-moon will submit a motion to the

  9. Fulltext PDF

    Indian Academy of Sciences (India)

    Unknown

    In recent times, newly emerging infectious diseases and their causative agents have become the focus of intense investigations by medical researchers and microbiologists, particularly virologists, since many of the causative organisms are viruses. One such disease which has created so much fear world wide is severe ...

  10. Search Results | Page 810 | IDRC - International Development ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 8091 - 8100 of 8491 ... Bringing research to farmers' fields in Malawi: Lizzie Shumba (Malawi). Research in Action. -. Raising the Bar for Microbiologists. Research in Action. -. The human consequences of animal health. Research in Action. Water. About WaDImena. Research in Action. -. Putting medical knowledge at ...

  11. Save Energy Now Assessments Results 2008 Detailed Report

    Energy Technology Data Exchange (ETDEWEB)

    Wright, Anthony L [ORNL; Martin, Michaela A [ORNL; Nimbalkar, Sachin U [ORNL; Quinn, James [U.S. Department of Energy; Glatt, Ms. Sandy [DOE Industrial Technologies Program; Orthwein, Mr. Bill [U.S. Department of Energy

    2010-09-01

    independently replicate the assessment process at the company's other facilities. Another important element of the Save Energy Now assessment process is the follow-up process used to identify how many of the recommended savings opportunities from individual assessments have been implemented in the industrial plants. Plant personnel involved with the Save Energy Now assessments are contacted 6 months, 12 months, and 24 months after individual assessments are completed to determine implementation results. A total of 260 Save Energy Now assessments were successfully completed in calendar year 2008. This means that a total of 718 assessments were completed in 2006, 2007, and 2008. As of July 2009, we have received a total of 239 summary reports from the ESAs that were conducted in year 2008. Hence, at the time that this report was prepared, 680 final assessment reports were completed (200 from year 2006, 241 from year 2007, and 239 from year 2008). The total identified potential cost savings from these 680 assessments is $1.1 billion per year, including natural gas savings of about 98 TBtu per year. These results, if fully implemented, could reduce CO{sub 2} emissions by about 8.9 million metric tons annually. When this report was prepared, data on implementation of recommended energy and cost savings measures from 488 Save Energy Now assessments were available. For these 488 plants, measures saving a total of $147 million per year have been implemented, measures that will save $169 million per year are in the process of being implemented, and plants are planning implementation of measures that will save another $239 million per year. The implemented recommendations are already achieving total CO{sub 2} reductions of about 1.8 million metric tons per year. This report provides a summary of the key results for the Save Energy Now assessments completed in 2008; details of the 6-month, 12-month, and 24-month implementation results obtained to date; and an evaluation of these

  12. Pictorial Detail and Recall in Adults and Children.

    Science.gov (United States)

    Ritchey, Gary H.

    1982-01-01

    Specific comparisons for a categorized set of items indicated that recall of detailed drawings and outlines was superior to recall of words. For an uncategorized set, outlines were recalled significantly better than pictures and both were recalled better than words. (Author/PN)

  13. Detail-enhanced multimodality medical image fusion based on gradient minimization smoothing filter and shearing filter.

    Science.gov (United States)

    Liu, Xingbin; Mei, Wenbo; Du, Huiqian

    2018-02-13

    In this paper, a detail-enhanced multimodality medical image fusion algorithm is proposed by using proposed multi-scale joint decomposition framework (MJDF) and shearing filter (SF). The MJDF constructed with gradient minimization smoothing filter (GMSF) and Gaussian low-pass filter (GLF) is used to decompose source images into low-pass layers, edge layers, and detail layers at multiple scales. In order to highlight the detail information in the fused image, the edge layer and the detail layer in each scale are weighted combined into a detail-enhanced layer. As directional filter is effective in capturing salient information, so SF is applied to the detail-enhanced layer to extract geometrical features and obtain directional coefficients. Visual saliency map-based fusion rule is designed for fusing low-pass layers, and the sum of standard deviation is used as activity level measurement for directional coefficients fusion. The final fusion result is obtained by synthesizing the fused low-pass layers and directional coefficients. Experimental results show that the proposed method with shift-invariance, directional selectivity, and detail-enhanced property is efficient in preserving and enhancing detail information of multimodality medical images. Graphical abstract The detailed implementation of the proposed medical image fusion algorithm.

  14. Are medical articles highlighting detailed statistics more cited?

    Directory of Open Access Journals (Sweden)

    Mike Thelwall

    2015-06-01

    Full Text Available When conducting a literature review, it is natural to search for articles and read their abstracts in order to select papers to read fully. Hence, informative abstracts are important to ensure that research is read. The description of a paper's methods may help to give confidence that a study is of high quality. This article assesses whether medical articles that mention three statistical methods, each of which is arguably indicative of a more detailed statistical analysis than average, are more highly cited. The results show that medical articles mentioning Bonferroni corrections, bootstrapping and effect size tend to be 7%, 8% and 15% more highly ranked for citations than average, respectively. Although this is consistent with the hypothesis that mentioning more detailed statistical techniques generate more highly cited research, these techniques may also tend to be used in more highly cited areas of Medicine.

  15. Detailed GEANT description of the SDC central calorimeters

    International Nuclear Information System (INIS)

    Glagolev, V.V.; Li, W.

    1994-01-01

    This article represents the very detailed simulation model of the SDC central calorimeters and some results which were obtained using that model. The central calorimeters structure was coded on the GEANT 3.15 base in the frame of the SDCSIM environment. The SDCSIM is the general shell for simulation of the SDC set-up. The calorimeters geometry has been coded according to the FNAL and ANL engineering drawings and engineering data file. SDC central calorimeters detailed description is extremely useful for different simulation tasks, for fast simulation program parameters tuning, for different geometry especially studying (local response nonuniformity from bulkheads in the e.m. calorimeter and from coil supports and many others) and for the interpretation of the experimental data from the calorimeters. This simulation model is very useful for tasks of the test beam modules calorimeter calibration and for calorimeter in situ calibration. 3 refs., 8 figs

  16. Addition of generic medication vouchers to a pharmacist academic detailing program: effects on the generic dispensing ratio in a physician-hospital organization.

    Science.gov (United States)

    Bhargava, Vinay; Greg, Mark E; Shields, Mark C

    2010-01-01

    Generic dispensing ratio (GDR) is an important measure of efficiency in pharmacy benefit management. A few studies have examined the effects of academic detailing or generic drug samples on GDR. On July 1, 2007, a physician-hospital organization (PHO) with a pay-for-performance incentive for generic utilization initiated a pilot generic medication voucher program that augmented its existing pharmacist-led academic detailing efforts. No published studies have examined the role of generic medication vouchers in promoting generic drug utilization. To determine if supplementing an existing academic detailing initiative in a PHO with a generic medication voucher program would be more effective in increasing the GDR compared with academic detailing alone. The intervention took place over the 9-month period from July 1, 2007, through March 31, 2008. Vouchers provided patients with the first fill of a 30-day supply of a generic drug at no cost to the patient for 8 specific generic medications obtained through a national community pharmacy chain. The study was conducted in a PHO composed of 7 hospitals and approximately 2,900 physicians (900 primary care providers [PCPs] and 2,000 specialists). Of the approximately 300 PCP practices, 21 practices with at least 2 physicians each were selected on the basis of high prescription volume (more than 500 pharmacy claims for the practice over a 12-month pre-baseline period) and low GDR (practice GDR less than 55% in the 12-month pre-baseline period). These 21 practices were then randomized to a control group of academic detailing alone or the intervention group that received academic detailing plus generic medication vouchers. One of 10 intervention groups declined to participate, and 2 of 11 control groups dropped out of the PHO. GDR was calculated monthly for all pharmacy claims including the 8 voucher medications. GDR was defined as the ratio of the total number of paid generic pharmacy claims divided by the total number of paid

  17. Detailed Chemical Kinetic Modeling of Hydrazine Decomposition

    Science.gov (United States)

    Meagher, Nancy E.; Bates, Kami R.

    2000-01-01

    The purpose of this research project is to develop and validate a detailed chemical kinetic mechanism for gas-phase hydrazine decomposition. Hydrazine is used extensively in aerospace propulsion, and although liquid hydrazine is not considered detonable, many fuel handling systems create multiphase mixtures of fuels and fuel vapors during their operation. Therefore, a thorough knowledge of the decomposition chemistry of hydrazine under a variety of conditions can be of value in assessing potential operational hazards in hydrazine fuel systems. To gain such knowledge, a reasonable starting point is the development and validation of a detailed chemical kinetic mechanism for gas-phase hydrazine decomposition. A reasonably complete mechanism was published in 1996, however, many of the elementary steps included had outdated rate expressions and a thorough investigation of the behavior of the mechanism under a variety of conditions was not presented. The current work has included substantial revision of the previously published mechanism, along with a more extensive examination of the decomposition behavior of hydrazine. An attempt to validate the mechanism against the limited experimental data available has been made and was moderately successful. Further computational and experimental research into the chemistry of this fuel needs to be completed.

  18. Detailed radon emanation mapping in Northern Latium

    International Nuclear Information System (INIS)

    Aumento, F.

    1993-01-01

    Detailed radon surveys over 5,000 km 2 of Northern Latium, covering the northern part of the volcanic province of Central Italy, commenced in the mid eighties as part of a geothermal exploration programme; the surveys have subsequently been continued and amplified with environmental protection in mind. The area is now covered by ground emission maps, radon levels in water supplies, emissions from the different lithologies and concentrations in houses. The high uraniferous content of the volcanics, the porous nature of the ubiquitous pyroclastics, and active geothermal systems in the area combine to convey to ground level high concentrations of radon. The emissions show strong lateral variations which are geologically and tectonically controlled, such that only detailed surveys reveal the extent and locations of anomalous radon emanations. Unfortunately, long ago towns often developed in strategic locations. For Northern Latium this means on volcanic highs formed by faulted tuff blocks, two geological features associated with particularly high radon emissions. As a result, in contrast to the low average indoor radon concentrations for the greater part of Italy, in some of these town the average values exceed 450 Bq/m 3 . (author). 1 fig

  19. Regional and Detailed Survey for Radon Activities in Soil-Gas and Groundwater in the Okchon Zone, Korea

    Science.gov (United States)

    Je, H.-K.; Chon, H.-T.

    2012-04-01

    The Okchon zone in Korea provides a typical example of natural geological materials enriched in potentially toxic elements including uranium which is parent nuclide for radon gas. For the purpose of radon radioactivity risk assessment, making the map of radon risk grade from Okchon zone, regional and detailed field surveys were carried out during 3 years. The study area is located in the central part of Korea, called the Okchon zone (about 5,100 km2), which occur in a 80km wide, northeast-trending belt that extends across the Korean Peninsula. The Okchon zone is underlain by metasedimentary rocks of unknown age that are composed mainly of black slate, phyllite, shale, and limestone. The three research areas (defined as Boeun, Chungju, and Nonsan) for detailed survey were selected from the results of regional survey. Results of detailed radon survey indicated a wide range of radon activities for soil-gases (148-1,843 pCi/L) and ground waters (23-5,540 pCi/L). About 15 percent of soil-gas samples exceeded 1,000 pCi/L and 84 percent of ground water samples exceeded the MCL (maximum contaminant level) of drinking water, 300 pCi/L, which proposed by U.S. Environmental Protection Agency in 1999. For detailed survey, radon activities of soil-gas and ground water were classified as bedrock geology, based on 1/50,000 geological map and field research. For soil-gas measurements, mean values of radon activity from black slate-shale (789 pCi/L) were highest among the other base rocks. And for groundwater measurements, mean value of radon activities were decreased in the order of granite (1,345 pCi/L) > black shale-slate (915 pCi/L) > metasediments (617 pCi/L). Result of indoor radon measurement from detailed survey areas showed that about 50% of houses exceeded the indoor guideline, 4 pCi/L. For the radon risk assessment in indoor environment showed that probability of lung cancer risk from the houses located on the granite base rock (3.0×10-2) was highest among the other

  20. The Soleil detailed pre-project report

    International Nuclear Information System (INIS)

    1999-01-01

    The aim of the joint CNRS/CEA Soleil project was to develop a facility equipped with several synchrotron radiation sources and their associated experimental devices in order to answer the estimated research needs in this domain for the 20 to 30 forthcoming years. This document is the detailed pre-project. It describes the studies carried out and relative to the infrastructures and buildings, to the accelerators and light sources (storage ring, injector, radiation production), to the program of experiments, to the computer science aspects, and to the administrative and organisational aspects. (J.S.)

  1. Ebolavirus Database: Gene and Protein Information Resource for Ebolaviruses

    Directory of Open Access Journals (Sweden)

    Rayapadi G. Swetha

    2016-01-01

    Full Text Available Ebola Virus Disease (EVD is a life-threatening haemorrhagic fever in humans. Even though there are many reports on EVD, the protein precursor functions and virulent factors of ebolaviruses remain poorly understood. Comparative analyses of Ebolavirus genomes will help in the identification of these important features. This prompted us to develop the Ebolavirus Database (EDB and we have provided links to various tools that will aid researchers to locate important regions in both the genomes and proteomes of Ebolavirus. The genomic analyses of ebolaviruses will provide important clues for locating the essential and core functional genes. The aim of EDB is to act as an integrated resource for ebolaviruses and we strongly believe that the database will be a useful tool for clinicians, microbiologists, health care workers, and bioscience researchers.

  2. MIV project: Simulator detailed design and integration for the EUROSIM

    DEFF Research Database (Denmark)

    Thuesen, Gøsta; Parisch, Manlio; Jørgensen, John Leif

    1997-01-01

    Under the ESA contract #11453/95/NL/JG(SC), aiming at assessing the feasibility of Rendez-vous and docking of unmanned spacecrafts, a reference mission scenario was defined. This report describes the detailed code developed for the contract, the code module interface and the interface to the EURO......Under the ESA contract #11453/95/NL/JG(SC), aiming at assessing the feasibility of Rendez-vous and docking of unmanned spacecrafts, a reference mission scenario was defined. This report describes the detailed code developed for the contract, the code module interface and the interface...

  3. Publications | Page 334 | IDRC - International Development ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 3331 - 3340 of 6381 ... Raising the Bar for Microbiologists. Dr Ana Sanchez was educated in Sweden and now lives and works in Canada, but she has never forgotten Honduras, where she was born. Today a Community Health Sciences professor at Brock University, she works with Dr Lourdes.

  4. Publications | Page 335 | IDRC - International Development ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Results 3341 - 3350 of 6384 ... Raising the Bar for Microbiologists. Dr Ana Sanchez was educated in Sweden and now lives and works in Canada, but she has never forgotten Honduras, where she was born. Today a Community Health Sciences professor at Brock University, she works with Dr Lourdes.

  5. Prof. T. S. Sadasivan | History | About IASc | Indian Academy of ...

    Indian Academy of Sciences (India)

    Career: Univ. of Lucknow, Dept. of Botany: Demonstrator 40-41; Fruit and Vegetable Preservation Lab., Lyaupur: Microbiologist 41-44; Univ. of Madras, Centre for Ad-vanced Studies in Botany: Director/Prof. 44-73; CSIR, Plant-based Lab.: Consultant 73-76; Birbal Sahni Professor, Lucknow 77-80; Vidyashram, Kodaikanal: ...

  6. The Architectural and Technical Consequences of Different Window Details in a Danish Passive House

    DEFF Research Database (Denmark)

    Brunsgaard, Camilla; Heiselberg, Per; Jensen, Rasmus Lund

    2008-01-01

     This paper focuses on a study of window details from "The Comfort Houses" in relation to "traditional" Danish construction solutions. The aim is to evaluate different ways of solving a window detail and to identify both architectural and technical consequences. It is important to investigate bot...... aspects of a detail because the best technical solution might not be the best architectural solution. A proposal from "The Comfort Houses" - a brick passive house, will be used as a basis....... This paper focuses on a study of window details from "The Comfort Houses" in relation to "traditional" Danish construction solutions. The aim is to evaluate different ways of solving a window detail and to identify both architectural and technical consequences. It is important to investigate both...

  7. 20 CFR 422.604 - Request for detailed information.

    Science.gov (United States)

    2010-04-01

    ... Section 422.604 Employees' Benefits SOCIAL SECURITY ADMINISTRATION ORGANIZATION AND PROCEDURES... whom you have premium responsibility, you may request detailed information as to the work histories of... error (as defined in § 422.602) and request review of the assignment if you have not already requested...

  8. Detail study of SiC MOSFET switching characteristics

    DEFF Research Database (Denmark)

    Li, Helong; Munk-Nielsen, Stig

    2014-01-01

    This paper makes detail study of the latest SiC MOSFETs switching characteristics in relation to gate driver maximum current, gate resistance, common source inductance and parasitic switching loop inductance. The switching performance of SiC MOSFETs in terms of turn on and turn off voltage...

  9. Implementation of a Detailed List of Subject Headings on Mormons and Mormonism within the Library of Congress Subject Heading System.

    Science.gov (United States)

    Birkinshaw, Scott B.; Chang, Stella

    Libraries in Utah have collected large numbers of materials on Mormonism and related topics and have a need to provide more detailed subject headings for these materials which the Library of Congress has lumped together under "Mormons and Mormonism." A list of subject headings which was developed for this purpose by a Committee of the…

  10. Analysis of the current–voltage curves and saturation currents in burner-stabilised premixed flames with detailed ion chemistry and transport models

    KAUST Repository

    Belhi, Memdouh

    2018-05-22

    Current-voltage, or i–V, curves are used in combustion to characterise the ionic structure of flames. The objective of this paper is to develop a detailed modelling framework for the quantitative prediction of the i–V curves in methane/air flames. Ion and electron transport coefficients were described using methods appropriate for charged species interactions. An ionic reaction mechanism involving cations, anions and free electrons was used, together with up-to-date rate coefficients and thermodynamic data. Because of the important role of neutral species in the ion production process, its prediction by the detailed AramcoMech 1.4 mechanism was optimised by using available experimental measurements. Model predictions were evaluated by comparing to i–V curves measured in atmospheric-pressure, premixed, burner-stabilised flames. A detailed evaluation of the reliability of ion kinetic and transport parameters adopted was performed. The model provides good quantitative agreement with experimental data for various conditions.

  11. Detailed analysis of the KAERI nTOF facility

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jong Woon; Lee, Young Ouk [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2016-06-15

    A project for building a neutron time-of-flight (nTOF) facility is progressing. We expect that the construction will start in early 2016. Before that, a detailed simulation based on the current architectural drawings was performed to optimize the performance of our facility. Currently, several parts had been modified or changed from the original design to reflect requirements such as the layout of the electron beam line, shape of the vacuum chamber producing a neutron beam, and the underground layout of the nTOF facility. Detailed analysis for these modifications has been done with MCNP simulation. An overview of our photo-neutron source and KAERI nTOF facility were introduced. The numerical simulations for heat deposition, source term, and radiation shielding of KAERI nTOF facility were performed and the results are discussed. We are expecting that the construction of the KAERI nTOF facility will start in early 2016, and these results will be used as basic data.

  12. PROVIDING R-TREE SUPPORT FOR MONGODB

    Directory of Open Access Journals (Sweden)

    L. Xiang

    2016-06-01

    Full Text Available Supporting large amounts of spatial data is a significant characteristic of modern databases. However, unlike some mature relational databases, such as Oracle and PostgreSQL, most of current burgeoning NoSQL databases are not well designed for storing geospatial data, which is becoming increasingly important in various fields. In this paper, we propose a novel method to provide R-tree index, as well as corresponding spatial range query and nearest neighbour query functions, for MongoDB, one of the most prevalent NoSQL databases. First, after in-depth analysis of MongoDB’s features, we devise an efficient tabular document structure which flattens R-tree index into MongoDB collections. Further, relevant mechanisms of R-tree operations are issued, and then we discuss in detail how to integrate R-tree into MongoDB. Finally, we present the experimental results which show that our proposed method out-performs the built-in spatial index of MongoDB. Our research will greatly facilitate big data management issues with MongoDB in a variety of geospatial information applications.

  13. Providing R-Tree Support for Mongodb

    Science.gov (United States)

    Xiang, Longgang; Shao, Xiaotian; Wang, Dehao

    2016-06-01

    Supporting large amounts of spatial data is a significant characteristic of modern databases. However, unlike some mature relational databases, such as Oracle and PostgreSQL, most of current burgeoning NoSQL databases are not well designed for storing geospatial data, which is becoming increasingly important in various fields. In this paper, we propose a novel method to provide R-tree index, as well as corresponding spatial range query and nearest neighbour query functions, for MongoDB, one of the most prevalent NoSQL databases. First, after in-depth analysis of MongoDB's features, we devise an efficient tabular document structure which flattens R-tree index into MongoDB collections. Further, relevant mechanisms of R-tree operations are issued, and then we discuss in detail how to integrate R-tree into MongoDB. Finally, we present the experimental results which show that our proposed method out-performs the built-in spatial index of MongoDB. Our research will greatly facilitate big data management issues with MongoDB in a variety of geospatial information applications.

  14. Automatic generation of medium-detailed 3D models of buildings based on CAD data

    NARCIS (Netherlands)

    Dominguez-Martin, B.; Van Oosterom, P.; Feito-Higueruela, F.R.; Garcia-Fernandez, A.L.; Ogayar-Anguita, C.J.

    2015-01-01

    We present the preliminary results of a work in progress which aims to obtain a software system able to automatically generate a set of diverse 3D building models with a medium level of detail, that is, more detailed that a mere parallelepiped, but not as detailed as a complete geometric

  15. Detailed anatomy of the abducens nerve in the lateral rectus muscle.

    Science.gov (United States)

    Nam, Yong Seok; Kim, In-Beom; Shin, Sun Young

    2017-10-01

    The aims of this study were to elucidate the detailed anatomy of the abducens nerve in the lateral rectus muscle (LRM) and the intramuscular innervation pattern using Sihler staining. In this cohort study, 32 eyes of 16 cadavers were assessed. Dissection was performed from the LRM origin to its insertion. The following distances were measured: from LRM insertion to the bifurcation point of the abducens nerve, from LRM insertion to the entry site of the superior branch or inferior branch, from the upper border of the LRM to the entry site of the superior branch, from the lower border of LRM to the entry site of inferior branch, and the widths of the main trunk and superior and inferior branches. The single trunk of the abducens nerve divided into two branches 37 mm from insertion of the LRM, and 22 of 32 (68.8%) orbits showed only two superior and inferior branches with no subdivision. The superior branch entered the LRM more anteriorly (P = 0.037) and the superior branch was thinner than the inferior branch (P = 0.040). The most distally located intramuscular nerve ending was observed at 52.9 ± 3.5% of the length of each muscle. Non-overlap between the superior and inferior intramuscular arborization of the nerve was detected in 27 of 32 cases (84.4%). Five cases (15.6%) showed definite overlap of the superior and inferior zones. This study revealed the detailed anatomy of the abducens nerve in the LRM and provides helpful information to understand abducens nerve palsy. Clin. Anat. 30:873-877, 2017. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

  16. Analysis of Detailed Energy Audits and Energy Use Measures of University Buildings

    Directory of Open Access Journals (Sweden)

    Kęstutis Valančius

    2011-12-01

    Full Text Available The paper explains the results of a detailed energy audit of the buildings of Vilnius Gediminas Technical University. Energy audits were performed with reference to the international scientific project. The article presents the methodology and results of detailed measurements of energy balance characteristics.Article in Lithuanian

  17. An alternative approach to contrast-detail testing of X-ray image intensifier systems

    International Nuclear Information System (INIS)

    Kotre, C.J.; Marshall, N.W.; Faulkner, K.

    1992-01-01

    The difficulties of making the results of threshold contrast-detail diameter tests on X-ray image intensifier systems consistent with published performance standards are discussed. The current approach to contrast-detail testing is described and an alternative method intended to give greater consistency for all image intensifier input field diameters proposed. The current and alternative test conditions are compared on two image intensifier systems. The results obtained show that the contrast-detail curves for image intensifier systems with a wide range of input field diameters can be effectively normalized to be directly comparable to a common reference standard by applying the proposed alternative test conditions. The implications of this result on the interpretation of the contrast-detail test are discussed. (author)

  18. Fabrication details for wire wrapped fuel assembly components

    International Nuclear Information System (INIS)

    Bosy, B.J.

    1978-09-01

    Extensive hydraulic testing of simulated LMFBR blanket and fuel assemblies is being carried out under this MIT program. The fabrication of these test assemblies has involved development of manufacturing procedures involving the wire wrapped pins and the flow housing. The procedures are described in detail in the report

  19. Detailed IR aperture measurements

    CERN Document Server

    Bruce, Roderik; Garcia Morales, Hector; Giovannozzi, Massimo; Hermes, Pascal Dominik; Mirarchi, Daniele; Quaranta, Elena; Redaelli, Stefano; Rossi, Carlo; Skowronski, Piotr Krzysztof; Wretborn, Sven Joel; CERN. Geneva. ATS Department

    2016-01-01

    MD 1673 was carried out on October 5 2016, in order to investigate in more detail the available aperture in the LHC high-luminosity insertions at 6.5 TeV and β∗=40 cm. Previous aperture measurements in 2016 during commissioning had shown that the available aperture is at the edge of protection, and that the aperture bottleneck at β∗=40 cm in certain cases is found in the separation plane instead of in the crossing plane. Furthermore, the bottlenecks were consistently found in close to the upstream end of Q3 on the side of the incoming beam, and not in Q2 on the outgoing beam as expected from calculations. Therefore, this MD aimed at measuring IR1 and IR5 separately (at 6.5 TeV and β∗=40 cm, for 185 µrad half crossing angle), to further localize the bottlenecks longitudinally using newly installed BLMs, investigate the difference in aperture between Q2 and Q3, and to see if any aperture can be gained using special orbit bumps.

  20. Detailed balance of the Feynman micromotor

    Science.gov (United States)

    Abbott, Derek; Davis, Bruce R.; Parrondo, Juan M. R.

    1999-09-01

    One existing implication of micromotors is that they can be powered by rectifying non-equilibrium thermal fluctuations or mechanical vibrations via the so-called Feynman- micromotor. An example of mechanical rectification is found in the batteryless wristwatch. The original concept was described in as early as 1912 by Smoluchowski and was later revisited in 1963 by Feynman, in the context of rectifying thermal fluctuations to obtain useful motion. It has been shown that, although rectification is impossible at equilibrium, it is possible for the Feynman-micromotor to perform work under non-equilibrium conditions. These concepts can now be realized by MEMS technology and may have exciting implications in biomedicine - where the Feynman- micromotor can be used to power a smart pill, for example. Previously, Feynman's analysis of the motor's efficiency has been shown to be flawed by Parrondo and Espanol. We now show there are further problems in Feynman's treatment of detailed balance. In order to design and understand this device correctly, the equations of detailed balance must be found. Feynman's approach was to use probabilities based on energies and we show that this is problematic. In this paper, we demonstrate corrected equations using level crossing probabilities instead. A potential application of the Feynman-micromotor is a batteryless nanopump that consists of a small MEMS chip that adheres to the skin of a patient and dispense nanoliter quantities of medication. Either mechanical or thermal rectification via a Feynman- micromotor, as the power source, is open for possible investigation.

  1. Utilization of a clinical microbiology service at a Cambodian paediatric hospital and its impact on appropriate antimicrobial prescribing.

    Science.gov (United States)

    Fox-Lewis, Shivani; Pol, Sreymom; Miliya, Thyl; Day, Nicholas P J; Turner, Paul; Turner, Claudia

    2018-02-01

    Antimicrobial resistance threatens human health worldwide. Antimicrobial misuse is a major driver of resistance. Promoting appropriate antimicrobial use requires an understanding of how clinical microbiology services are utilized, particularly in resource-limited settings. To assess the appropriateness of antimicrobial prescribing and the factors affecting utilization of the established clinical microbiology service (CMS). The CMS comprises the microbiology laboratory, clinical microbiologists (infection doctors) and antimicrobial treatment guidelines. This mixed-methods study was conducted at a non-governmental Cambodian paediatric hospital. Empirical and post-culture antimicrobial prescriptions were reviewed from medical records. The random sample included 10 outpatients per week in 2016 (retrospective) and 20 inpatients per week for 4 weeks in the medical, neonatal and intensive care wards (prospective). Post-culture prescriptions were assessed in patients with positive blood and cerebrospinal fluid cultures from 1 January 2014 to 31 December 2016. Focus group discussions and semi-structured interviews with clinicians explored barriers and facilitators to use of the CMS. Only 31% of outpatients were prescribed empirical antimicrobials. Post-culture prescriptions (394/443, 89%) were more likely to be appropriate than empirical prescriptions (447/535, 84%), based on treatment guidelines, microbiology advice and antimicrobial susceptibility test results (P = 0.015). Being comprehensive, accessible and trusted enabled CMS utilization. Clinical microbiologists provided a crucial human interface between the CMS and physicians. The main barriers were a strong clinical hierarchy and occasional communication difficulties. Antimicrobial prescribing in this hospital was largely appropriate. A culturally appropriate human interface linking the laboratory and physicians is essential in providing effective microbiology services and ensuring appropriate antimicrobial

  2. Remembering the Specific Visual Details of Presented Objects: Neuroimaging Evidence for Effects of Emotion

    Science.gov (United States)

    Kensinger, Elizabeth A.; Schacter, Daniel L.

    2007-01-01

    Memories can be retrieved with varied amounts of visual detail, and the emotional content of information can influence the likelihood that visual detail is remembered. In the present fMRI experiment (conducted with 19 adults scanned using a 3T magnet), we examined the neural processes that correspond with recognition of the visual details of…

  3. Generalized procedures for determining inspection sample sizes (related to quantitative measurements). Vol. 1: Detailed explanations

    International Nuclear Information System (INIS)

    Jaech, J.L.; Lemaire, R.J.

    1986-11-01

    Generalized procedures have been developed to determine sample sizes in connection with the planning of inspection activities. These procedures are based on different measurement methods. They are applied mainly to Bulk Handling Facilities and Physical Inventory Verifications. The present report attempts (i) to assign to appropriate statistical testers (viz. testers for gross, partial and small defects) the measurement methods to be used, and (ii) to associate the measurement uncertainties with the sample sizes required for verification. Working papers are also provided to assist in the application of the procedures. This volume contains the detailed explanations concerning the above mentioned procedures

  4. Utilization of Large Scale Surface Models for Detailed Visibility Analyses

    Science.gov (United States)

    Caha, J.; Kačmařík, M.

    2017-11-01

    This article demonstrates utilization of large scale surface models with small spatial resolution and high accuracy, acquired from Unmanned Aerial Vehicle scanning, for visibility analyses. The importance of large scale data for visibility analyses on the local scale, where the detail of the surface model is the most defining factor, is described. The focus is not only the classic Boolean visibility, that is usually determined within GIS, but also on so called extended viewsheds that aims to provide more information about visibility. The case study with examples of visibility analyses was performed on river Opava, near the Ostrava city (Czech Republic). The multiple Boolean viewshed analysis and global horizon viewshed were calculated to determine most prominent features and visibility barriers of the surface. Besides that, the extended viewshed showing angle difference above the local horizon, which describes angular height of the target area above the barrier, is shown. The case study proved that large scale models are appropriate data source for visibility analyses on local level. The discussion summarizes possible future applications and further development directions of visibility analyses.

  5. Urban scale air quality modelling using detailed traffic emissions estimates

    Science.gov (United States)

    Borrego, C.; Amorim, J. H.; Tchepel, O.; Dias, D.; Rafael, S.; Sá, E.; Pimentel, C.; Fontes, T.; Fernandes, P.; Pereira, S. R.; Bandeira, J. M.; Coelho, M. C.

    2016-04-01

    The atmospheric dispersion of NOx and PM10 was simulated with a second generation Gaussian model over a medium-size south-European city. Microscopic traffic models calibrated with GPS data were used to derive typical driving cycles for each road link, while instantaneous emissions were estimated applying a combined Vehicle Specific Power/Co-operative Programme for Monitoring and Evaluation of the Long-range Transmission of Air Pollutants in Europe (VSP/EMEP) methodology. Site-specific background concentrations were estimated using time series analysis and a low-pass filter applied to local observations. Air quality modelling results are compared against measurements at two locations for a 1 week period. 78% of the results are within a factor of two of the observations for 1-h average concentrations, increasing to 94% for daily averages. Correlation significantly improves when background is added, with an average of 0.89 for the 24 h record. The results highlight the potential of detailed traffic and instantaneous exhaust emissions estimates, together with filtered urban background, to provide accurate input data to Gaussian models applied at the urban scale.

  6. Author Details

    African Journals Online (AJOL)

    Rich, E. Vol 107, No 5 (2017) - Articles Codeine misuse and dependence in South Africa: Perspectives of addiction treatment providers. Abstract PDF. ISSN: 0256-95749. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms ...

  7. Probabilistic Model for Fatigue Crack Growth in Welded Bridge Details

    DEFF Research Database (Denmark)

    Toft, Henrik Stensgaard; Sørensen, John Dalsgaard; Yalamas, Thierry

    2013-01-01

    In the present paper a probabilistic model for fatigue crack growth in welded steel details in road bridges is presented. The probabilistic model takes the influence of bending stresses in the joints into account. The bending stresses can either be introduced by e.g. misalignment or redistribution...... of stresses in the structure. The fatigue stress ranges are estimated from traffic measurements and a generic bridge model. Based on the probabilistic models for the resistance and load the reliability is estimated for a typical welded steel detail. The results show that large misalignments in the joints can...

  8. Detailed behavioral modeling of bang-bang phase detectors

    DEFF Research Database (Denmark)

    Jiang, Chenhui; Andreani, Pietro; Keil, U. D.

    2006-01-01

    In this paper, the metastability of current-mode logic (CML) latches and flip-flops is studied in detail. Based on the results of this analysis, a behavioral model of bang-bang phase detectors (BBPDs) is proposed, which is able to reliably capture the critical deadzone effect. The impact of jitter...

  9. Satellite telemetry of Afrotropical ducks: methodological details and ...

    African Journals Online (AJOL)

    Despite widespread and increasing use of solarpowered satellite transmitters to tag wild birds, there are few published articles that detail how transmitters should be attached to different species and even fewer assessments of the overall field success of telemetry projects. The scarcity of this information makes it difficult to ...

  10. A detailed study of FDIRC prototype with waveform digitizing electronics in cosmic ray telescope using 3D tracks

    Science.gov (United States)

    Nishimura, K.; Dey, B.; Aston, D.; Leith, D. W. G. S.; Ratcliff, B.; Roberts, D.; Ruckman, L.; Shtol, D.; Varner, G. S.; Va'vra, J.

    2013-02-01

    We present a detailed study of a novel Cherenkov imaging detector called the Focusing DIRC (FDIRC) with waveform digitizing electronics. In this study, the FDIRC prototype has been instrumented with seven Hamamatsu H-8500 MaPMTs. Waveforms from 384 pixels are digitized with waveform sampling electronics based on the BLAB2 ASIC, operating at a sampling speed of ∼2.5 GSa/s. The FDIRC prototype was tested in a large cosmic ray telescope (CRT) providing 3D muon tracks with ∼1.5 mrad angular resolution and muon energy of Emuon> 1.6 GeV. In this study we provide a detailed analysis of the tails in the Cherenkov angle distribution as a function of various variables, compare experimental results with simulation, and identify the major contributions to the tails. We demonstrate that to see the full impact of these tails on the Cherenkov angle resolution, it is crucial to use 3D tracks, and have a full understanding of the role of reconstruction ambiguities. These issues could not be fully explored in previous FDIRC studies where the beam was perpendicular to the quartz radiator bars. This work is relevant for the final FDIRC prototype of the PID detector at SuperB, which will be tested this year in the CRT setup.

  11. A Detailed Study of FDIRC Prototype with Waveform Digitizing Electronics in Cosmic Ray Telescope Using 3D Tracks

    International Nuclear Information System (INIS)

    Nishimura, K.; Dey, B.; Aston, D.; Leith, D.W.G.S.; Ratcliff, B.; Roberts, D.; Ruckman, L.; Shtol, D.; Varner, G.S.; Va'vra, J.

    2012-01-01

    We present a detailed study of a novel Cherenkov imaging detector called the Focusing DIRC (FDIRC) with waveform digitizing electronics. In this test study, the FDIRC prototype has been instrumented with seven Hamamatsu H-8500 MaPMTs. Waveforms from ∼450 pixels are digitized with waveform sampling electronics based on the BLAB2 ASIC, operating at a sampling speed of ∼2.5 GSa/s. The FDIRC prototype was tested in a large cosmic ray telescope (CRT) providing 3D muon tracks with ∼1.5 mrad angular resolution and muon energy of E muon > 1.6 GeV. In this study we provide a detailed analysis of the tails in the Cherenkov angle distribution as a function of various variables, compare experimental results with simulation, and identify the major contributions to the tails. We demonstrate that to see the full impact of these tails on the Cherenkov angle resolution, it is crucial to use 3D tracks, and have a full understanding of the role of ambiguities. These issues could not be fully explored in previous FDIRC studies where the beam was perpendicular to the quartz radiator bars. This work is relevant for the final FDIRC prototype of the PID detector at SuperB, which will be tested this year in the CRT setup.

  12. Author Details

    African Journals Online (AJOL)

    Kruger, HB. Vol 29, No 1 (2004) - Articles Addressing domestic violence: to what extent does the law provide effective measures? Abstract. ISSN: 0258-252X. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions ...

  13. James Bernard Russell: Scholar, collaborator, mentor

    Science.gov (United States)

    At the time of his untimely death in 2009, ARS scientist Dr. James B. Russell had established himself as the premier rumen microbiologist of his generation. Dr. Russell’s many contributions to the field, including much of the early work on the Cornell Net Carbohydrate System model, were the product ...

  14. An examination of the association between interviewer question type and story-grammar detail in child witness interviews about abuse.

    Science.gov (United States)

    Feltis, Brooke B; Powell, Martine B; Snow, Pamela C; Hughes-Scholes, Carolyn H

    2010-06-01

    This study compared the effects of open-ended versus specific questions, and various types of open-ended questions, in eliciting story-grammar detail in child abuse interviews. The sample included 34 police interviews with child witnesses aged 5-15 years (M age=9 years, 9 months). The interviewers' questions and their relative sub-types were classified according to definitions reported in the child interview training literature. The children's responses were classified according to the proportion of story grammar and the prevalence of individual story grammar elements as defined by Stein and Glenn (1979). Open-ended questions were more effective at eliciting story grammar than specific questions. This finding was revealed across three age groups, two interview phases and irrespective of how question effectiveness was measured. However, not all types of open-ended questions were equally effective. Open-ended questions that encouraged a broad response, or asked the child to elaborate on a part of their account, elicited more story-grammar detail compared to open-ended questions that requested clarification of concepts or descriptions of the next (or another) activity or detail within a sequence. This study demonstrates that children's ability to provide story-grammar detail is maximised when there is minimal prompting from the interviewer. Given the association between story grammar production and victim credibility, greater guidance is warranted in interviewer training programs in relation to the effects and administration of different types of open-ended questions. Copyright 2010 Elsevier Ltd. All rights reserved.

  15. Author Details

    African Journals Online (AJOL)

    Falokade, O A. Vol 8 (2006) - Articles Providing For The Gifted And Talented Children With Disability In Nigeria: A Rethink Abstract. ISSN: 1119-7056. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of Use ...

  16. Selection of detailed items for periodic safety review on PWR radwaste management system

    Energy Technology Data Exchange (ETDEWEB)

    Sung, K. B.; Ahn, Y. S.; Park, Y. S.; Kim, S. H.; Kim, J. T. [Korea Hydric and Nuclear Power Company, Taejon (Korea, Republic of)

    2003-10-01

    Selection of detailed-items for Periodic Safety Review on PWR radwaste management system, the main component could be faithfully clarified according to the purpose of establishment on each system and basic purpose. It is proper to select detailed-items those of radioactivities in the reactor coolant activity levels and the released volume of liquid and gaseous radioactive material on safety performance. It's also proper to select solid radwaste production quantities as detailed-item that it would be predict the next ten years trends after PSR.

  17. Determinants of patient loyalty to healthcare providers: An integrative review.

    Science.gov (United States)

    Zhou, Wei-Jiao; Wan, Qiao-Qin; Liu, Cong-Ying; Feng, Xiao-Lin; Shang, Shao-Mei

    2017-08-01

    Patient loyalty is key to business success for healthcare providers and also for patient health outcomes. This study aims to identify determinants influencing patient loyalty to healthcare providers and propose an integrative conceptual model of the influencing factors. PubMed, CINAHL, OVID, ProQuest and Elsevier Science Direct databases were searched. Publications about determinants of patient loyalty to health providers were screened, and 13 articles were included. Date of publication, location of the research, sample details, objectives and findings/conclusions were extracted for 13 articles. Thirteen studies explored eight determinants: satisfaction, quality, value, hospital brand image, trust, commitment, organizational citizenship behavior and customer complaints. The integrated conceptual model comprising all the determinants demonstrated the significant positive direct impact of quality on satisfaction and value, satisfaction on trust and commitment, trust on commitment and loyalty, and brand image on quality and loyalty. This review identifies and models the determinants of patient loyalty to healthcare providers. Further studies are needed to explore the influence of trust, commitment, and switching barriers on patient loyalty. © The Author 2017. Published by Oxford University Press in association with the International Society for Quality in Health Care. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com

  18. Implementing academic detailing for breast cancer screening in underserved communities

    Directory of Open Access Journals (Sweden)

    Ashford Alfred R

    2007-12-01

    Full Text Available Abstract Background African American and Hispanic women, such as those living in the northern Manhattan and the South Bronx neighborhoods of New York City, are generally underserved with regard to breast cancer prevention and screening practices, even though they are more likely to die of breast cancer than are other women. Primary care physicians (PCPs are critical for the recommendation of breast cancer screening to their patients. Academic detailing is a promising strategy for improving PCP performance in recommending breast cancer screening, yet little is known about the effects of academic detailing on breast cancer screening among physicians who practice in medically underserved areas. We assessed the effectiveness of an enhanced, multi-component academic detailing intervention in increasing recommendations for breast cancer screening within a sample of community-based urban physicians. Methods Two medically underserved communities were matched and randomized to intervention and control arms. Ninety-four primary care community (i.e., not hospital based physicians in northern Manhattan were compared to 74 physicians in the South Bronx neighborhoods of the New York City metropolitan area. Intervention participants received enhanced physician-directed academic detailing, using the American Cancer Society guidelines for the early detection of breast cancer. Control group physicians received no intervention. We conducted interviews to measure primary care physicians' self-reported recommendation of mammography and Clinical Breast Examination (CBE, and whether PCPs taught women how to perform breast self examination (BSE. Results Using multivariate analyses, we found a statistically significant intervention effect on the recommendation of CBE to women patients age 40 and over; mammography and breast self examination reports increased across both arms from baseline to follow-up, according to physician self-report. At post-test, physician

  19. Increased interestingness of extraneous details in a multimedia science presentation leads to decreased learning.

    Science.gov (United States)

    Mayer, Richard E; Griffith, Emily; Jurkowitz, Ilana T N; Rothman, Daniel

    2008-12-01

    In Experiment 1, students received an illustrated booklet, PowerPoint presentation, or narrated animation that explained 6 steps in how a cold virus infects the human body. The material included 6 high-interest details mainly about the role of viruses in sex or death (high group) or 6 low-interest details consisting of facts and health tips about viruses (low group). The low group outperformed the high group across all 3 media on a subsequent test of problem-solving transfer (d = .80) but not retention (d = .05). In Experiment 2, students who studied a PowerPoint lesson explaining the steps in how digestion works performed better on a problem-solving transfer test if the lesson contained 7 low-interest details rather than 7 high-interest details (d = .86), but the groups did not differ on retention (d = .26). In both experiments, as the interestingness of details was increased, student understanding decreased (as measured by transfer). Results are consistent with a cognitive theory of multimedia learning, in which highly interesting details sap processing capacity away from deeper cognitive processing of the core material during learning. PsycINFO Database Record (c) 2008 APA, all rights reserved.

  20. Detailed balance theory of excitonic and bulk heterojunction solar cells

    Science.gov (United States)

    Kirchartz, Thomas; Mattheis, Julian; Rau, Uwe

    2008-12-01

    A generalized solar cell model for excitonic and classical bipolar solar cells describes the combined transport and interaction of electrons, holes, and excitons in accordance with the principle of detailed balance. Conventional inorganic solar cells, single-phase organic solar cells and bulk heterojunction solar cells, i.e., nanoscale mixtures of two organic materials, are special cases of this model. For high mobilities, the compatibility with the principle of detailed balance ensures that our model reproduces the Shockley-Queisser limit irrespective of how the energy transport is achieved. For less ideal devices distinct differences become visible between devices that are described by linear differential equations and those with nonlinear effects, such as a voltage-dependent collection in bipolar p-i-n -type devices. These differences in current-voltage characteristics are also decisive for the validity of the reciprocity theorem between photovoltaic quantum efficiency and electroluminescent emission. Finally, we discuss the effect of band offset at the heterointerface in a bulk heterojunction cell and the effect of the average distances between these heterointerfaces on the performance of a solar cell in order to show how our detailed balance model includes also these empirically important quantities.

  1. 34 CFR 5.16 - Deletion of identifying details.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Deletion of identifying details. 5.16 Section 5.16 Education Office of the Secretary, Department of Education AVAILABILITY OF INFORMATION TO THE PUBLIC PURSUANT TO PUB. L. 90-23 (Eff. until 7-14-10) What Records Are Available § 5.16 Deletion of identifying...

  2. Level of detail in 3D city models

    NARCIS (Netherlands)

    Biljecki, F.

    2017-01-01

    The concept of level of detail (LOD) describes the content of 3D city models and it plays an essential role during their life cycle. On one hand it comes akin to the concepts of scale in cartography and LOD in computer graphics, on the other hand it is a standalone concept that requires attention.

  3. Energy Provider: Delivered Energy Efficiency: A global stock-taking based on case studies

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2013-06-01

    In 2011 the IEA and the Regulatory Assistance Project (RAP) took on a work programme focused on the role of energy providers in delivering energy efficiency to end-users. This work was part of the IEA’s contribution to the PEPDEE Task Group, which falls under the umbrella of the International Partnership on Energy Efficiency Cooperation (IPEEC). In addition to organizing regional dialogues between governments, regulators, and energy providers, the PEPDEE work stream conducted global stock-takings of regulatory mechanisms adopted by governments to obligate or encourage energy providers to delivery energy savings and the energy savings activities of energy providers. For its part the IEA conducted a global review of energy provider-delivered energy savings programmes. The IEA reached out to energy providers to identify the energy savings activities they engaged in. Some 250 energy saving activities were considered, and 41 detailed case studies spanning 18 countries were developed. Geographic balance was a major consideration, and much effort was expended identifying energy provider-delivered energy savings case studies from around the world. Taken together these case studies represent over USD 1 billion in annual spending, or about 8% of estimated energy provider spending on energy efficiency.

  4. Development of a global computable general equilibrium model coupled with detailed energy end-use technology

    International Nuclear Information System (INIS)

    Fujimori, Shinichiro; Masui, Toshihiko; Matsuoka, Yuzuru

    2014-01-01

    Highlights: • Detailed energy end-use technology information is considered within a CGE model. • Aggregated macro results of the detailed model are similar to traditional model. • The detailed model shows unique characteristics in the household sector. - Abstract: A global computable general equilibrium (CGE) model integrating detailed energy end-use technologies is developed in this paper. The paper (1) presents how energy end-use technologies are treated within the model and (2) analyzes the characteristics of the model’s behavior. Energy service demand and end-use technologies are explicitly considered, and the share of technologies is determined by a discrete probabilistic function, namely a Logit function, to meet the energy service demand. Coupling with detailed technology information enables the CGE model to have more realistic representation in the energy consumption. The proposed model in this paper is compared with the aggregated traditional model under the same assumptions in scenarios with and without mitigation roughly consistent with the two degree climate mitigation target. Although the results of aggregated energy supply and greenhouse gas emissions are similar, there are three main differences between the aggregated and the detailed technologies models. First, GDP losses in mitigation scenarios are lower in the detailed technology model (2.8% in 2050) as compared with the aggregated model (3.2%). Second, price elasticity and autonomous energy efficiency improvement are heterogeneous across regions and sectors in the detailed technology model, whereas the traditional aggregated model generally utilizes a single value for each of these variables. Third, the magnitude of emissions reduction and factors (energy intensity and carbon factor reduction) related to climate mitigation also varies among sectors in the detailed technology model. The household sector in the detailed technology model has a relatively higher reduction for both energy

  5. Detailed observations of NGC 4151 with IUE

    International Nuclear Information System (INIS)

    Bromage, G.E.; Boksenberg, A.; Clavel, J.

    1984-12-01

    A detailed analysis is presented of the ultraviolet (lambdalambda 1150-3200 A) absorption spectrum of the NGC 4151 Seyfert nucleus. The IUE data base consisted of high dispersion (Δlambda approx. 0.2 A) spectra at 5 epochs, and 137 low dispersion (Δlambda approx. 4-8 A) spectra at 31 epochs from 1978 February to 1980 May, together with further low dispersion data in 1980-81 with NGC 4151 in a very faint quiescent state. (author)

  6. Detailed design of product oriented manufacturing systems

    OpenAIRE

    Silva, Sílvio Carmo; Alves, Anabela Carvalho

    2006-01-01

    This paper presents a procedure for the detailed design and redesign of manufacturing systems within a framework of constantly fitting production system configuration to the varying production needs of products. With such an approach is achieved the design of Product Oriented Manufacturing Systems – POMS. This approach is in opposition to the fitting, before hand, of a production system to all products within a company. In this case is usual to adopt a Function Oriented Manufactur...

  7. Direct numerical simulations of reacting flows with detailed chemistry using many-core/GPU acceleration

    KAUST Repository

    Herná ndez Pé rez, Francisco E.; Mukhadiyev, Nurzhan; Xu, Xiao; Sow, Aliou; Lee, Bok Jik; Sankaran, Ramanan; Im, Hong G.

    2018-01-01

    A new direct numerical simulation (DNS) code for multi-component gaseous reacting flows has been developed at KAUST, with the state-of-the-art programming model for next generation high performance computing platforms. The code, named KAUST Adaptive Reacting Flows Solver (KARFS), employs the MPI+X programming, and relies on Kokkos for “X” for performance portability to multi-core, many-core and GPUs, providing innovative software development while maintaining backward compatibility with established parallel models and legacy code. The capability and potential of KARFS to perform DNS of reacting flows with large, detailed reaction mechanisms is demonstrated with various model problems involving ignition and turbulent flame propagations with varying degrees of chemical complexities.

  8. Detail design of a 10.4-m stretched-membrane dish. Phase 2, Final report

    Energy Technology Data Exchange (ETDEWEB)

    1994-01-01

    This report describes efforts conducted under Tasks 3 and 4 of the second phase of the project to develop a single-element stretched-membrane dish concept to reduce the cost of a high-performance concentrating solar collector. We completed the detailed design for such a collector suitable to drive a 25-kWe Stirling motor generator. The design includes the collectors, optical element, the drive, and support systems. The aperture of the optical element was sized to provide the required energy to the engine based on test data and analytical models of the concentrator receiver, and engine. The design of the optical element was improved based on experience gained from the design, fabrication, and testing of several prototypes.

  9. The hands in metabolic skeletal diseases 1. A method of high-detailed contact radiography

    International Nuclear Information System (INIS)

    Shotemor, Sh.Sh.; Tret'yakov, A.E.

    1982-01-01

    A method of high-detailed contact radiography of the hands consists in the the screenless x-ray on the fine grained technical film employing microfocus with consecutive optical enlargement of the appearance. Various specimens of home-made tecinical film have been tried, the best results were obtained with the PT-5 film type (an opportunity of 7-fold optical magnification without interfering effect of the emulsion granularity). The method provides for a significant diagnostic advantage, affording to reveal minimal manifestations of subperiosteal, intracortical, and enosteal bone tissue resorption, as well as tiny calcinates in soft tissues. Pathological bone disorders were discovered in 63 out of 142 examined patients, suspected of metabolic diseases of the skeleton [ru

  10. Direct numerical simulations of reacting flows with detailed chemistry using many-core/GPU acceleration

    KAUST Repository

    Hernández Pérez, Francisco E.

    2018-03-29

    A new direct numerical simulation (DNS) code for multi-component gaseous reacting flows has been developed at KAUST, with the state-of-the-art programming model for next generation high performance computing platforms. The code, named KAUST Adaptive Reacting Flows Solver (KARFS), employs the MPI+X programming, and relies on Kokkos for “X” for performance portability to multi-core, many-core and GPUs, providing innovative software development while maintaining backward compatibility with established parallel models and legacy code. The capability and potential of KARFS to perform DNS of reacting flows with large, detailed reaction mechanisms is demonstrated with various model problems involving ignition and turbulent flame propagations with varying degrees of chemical complexities.

  11. Devil's in the (diffuse) detail

    International Nuclear Information System (INIS)

    Welberry, R.

    2006-07-01

    X-ray crystallography is an important workhorse in the world of solid-state chemistry. However, while it's a powerful tool in determining the average structure in a crystal lattice, conventional crystallography is very limited when it comes to understanding nano-scale disorder within that crystal structure. And when it comes to understanding the properties of many important materials, the devil is in the detail. X-ray diffraction is still one of the keys to understanding this finer scale structure but using it requires a capacity to read between the lines - to understand the diffuse diffraction that most crystallography ignores. Scientists at the Research School of Chemistry are leading the world in this field. Their work on modelling nano-scaled disorder using diffuse diffraction is opening up new possibilities in understanding and modifying many of our most important materials

  12. Routine use of point-of-care tests: usefulness and application in clinical microbiology.

    Science.gov (United States)

    Clerc, O; Greub, G

    2010-08-01

    Point-of-care (POC) tests offer potentially substantial benefits for the management of infectious diseases, mainly by shortening the time to result and by making the test available at the bedside or at remote care centres. Commercial POC tests are already widely available for the diagnosis of bacterial and viral infections and for parasitic diseases, including malaria. Infectious diseases specialists and clinical microbiologists should be aware of the indications and limitations of each rapid test, so that they can use them appropriately and correctly interpret their results. The clinical applications and performance of the most relevant and commonly used POC tests are reviewed. Some of these tests exhibit insufficient sensitivity, and should therefore be coupled to confirmatory tests when the results are negative (e.g. Streptococcus pyogenes rapid antigen detection test), whereas the results of others need to be confirmed when positive (e.g. malaria). New molecular-based tests exhibit better sensitivity and specificity than former immunochromatographic assays (e.g. Streptococcus agalactiae detection). In the coming years, further evolution of POC tests may lead to new diagnostic approaches, such as panel testing, targeting not just a single pathogen, but all possible agents suspected in a specific clinical setting. To reach this goal, the development of serology-based and/or molecular-based microarrays/multiplexed tests will be needed. The availability of modern technology and new microfluidic devices will provide clinical microbiologists with the opportunity to be back at the bedside, proposing a large variety of POC tests that will allow quicker diagnosis and improved patient care.

  13. Numerical models: Detailing and simulation techniques aimed at comparison with experimental data, support to test result interpretation

    International Nuclear Information System (INIS)

    Lin Chiwen

    2001-01-01

    This part of the presentation discusses the modelling details required and the simulation techniques available for analyses, facilitating the comparison with the experimental data and providing support for interpretation of the test results. It is organised to cover the following topics: analysis inputs; basic modelling requirements for reactor coolant system; method applicable for reactor cooling system; consideration of damping values and integration time steps; typical analytic models used for analysis of reactor pressure vessel and internals; hydrodynamic mass and fluid damping for the internal analysis; impact elements for fuel analysis; and PEI theorem and its applications. The intention of these topics is to identify the key parameters associated with models of analysis and analytical methods. This should provide proper basis for useful comparison with the test results

  14. DETAILED MODELLING OF CHARGING BEHAVIOUR OF SMART SOLAR TANKS

    DEFF Research Database (Denmark)

    Fan, Jianhua; Andersen, Elsa; Furbo, Simon

    2010-01-01

    The charging behaviour of smart solar tanks for solar combisystems for one-family houses is investigated with detailed Computational Fluid Dynamics (CFD) modelling and Particle Image Velocimetry (PIV) measurements. The smart solar tank can be charged with a variable auxiliary volume fitted...... or by an electric heating element in a side-arm mounted on the side of the tank. Detailed CFD models of the smart tanks are built with different mesh densities in the tank and in the side-arm. The thermal conditions of the tank during charging are calculated with the CFD models. The fluid flow and temperature...... by the mesh densities, the distribution of computational cells, the physical model and time steps used in the simulations. The findings of the investigations will be used as guidance for creation of CFD models for optimal design of smart solar tanks....

  15. Community Renewable Energy Deployment Provides Replicable Examples of Clean Energy Projects (Fact Sheet)

    Energy Technology Data Exchange (ETDEWEB)

    2012-09-01

    This fact sheet describes the U.S. Department of Energy's Community Renewable Energy Deployment (CommRE) program, which is a more than $20 million effort funded through the American Recovery and Reinvestment Act of 2009, to promote investment in clean energy solutions and provide real-life examples for other local governments, campuses, and small utilities to replicate. Five community-based renewable energy projects received funding from DOE through the CommRE and their progress is detailed.

  16. Staphylococcus aureus: molecular and clinical aspects

    National Research Council Canada - National Science Library

    Ala'Aldeen, Dlawer A. A; Hiramatsu, Keiichi

    2004-01-01

    ... Lecturer position in 1994 at the Division of Microbiology in Nottingham's University Hospital. He trained in clinical microbiology, obtained MRCPath and became a consultant microbiologist in the same hospital, being promoted to Reader in 1997 and Professor in 2002. He teaches clinical microbiology to undergraduate and postgraduate students and is the fo...

  17. Federal Funds for Research and Development. Fiscal Years 1982, 1983, and 1984. Volume XXXII. Detailed Statistical Tables. Surveys of Science Resources Series.

    Science.gov (United States)

    National Science Foundation, Washington, DC. Div. of Science Resources Studies.

    Detailed statistical tables on federal funds for research and development (R&D) are provided in this document. Tables are organized into the following sections: research, development, and R&D plant; R&D--agency, character of work, and performer; total research--agency, performer, and field of science; basic research--agency, performer,…

  18. Building a semantic web-based metadata repository for facilitating detailed clinical modeling in cancer genome studies.

    Science.gov (United States)

    Sharma, Deepak K; Solbrig, Harold R; Tao, Cui; Weng, Chunhua; Chute, Christopher G; Jiang, Guoqian

    2017-06-05

    Detailed Clinical Models (DCMs) have been regarded as the basis for retaining computable meaning when data are exchanged between heterogeneous computer systems. To better support clinical cancer data capturing and reporting, there is an emerging need to develop informatics solutions for standards-based clinical models in cancer study domains. The objective of the study is to develop and evaluate a cancer genome study metadata management system that serves as a key infrastructure in supporting clinical information modeling in cancer genome study domains. We leveraged a Semantic Web-based metadata repository enhanced with both ISO11179 metadata standard and Clinical Information Modeling Initiative (CIMI) Reference Model. We used the common data elements (CDEs) defined in The Cancer Genome Atlas (TCGA) data dictionary, and extracted the metadata of the CDEs using the NCI Cancer Data Standards Repository (caDSR) CDE dataset rendered in the Resource Description Framework (RDF). The ITEM/ITEM_GROUP pattern defined in the latest CIMI Reference Model is used to represent reusable model elements (mini-Archetypes). We produced a metadata repository with 38 clinical cancer genome study domains, comprising a rich collection of mini-Archetype pattern instances. We performed a case study of the domain "clinical pharmaceutical" in the TCGA data dictionary and demonstrated enriched data elements in the metadata repository are very useful in support of building detailed clinical models. Our informatics approach leveraging Semantic Web technologies provides an effective way to build a CIMI-compliant metadata repository that would facilitate the detailed clinical modeling to support use cases beyond TCGA in clinical cancer study domains.

  19. Visual long-term memory has a massive storage capacity for object details.

    Science.gov (United States)

    Brady, Timothy F; Konkle, Talia; Alvarez, George A; Oliva, Aude

    2008-09-23

    One of the major lessons of memory research has been that human memory is fallible, imprecise, and subject to interference. Thus, although observers can remember thousands of images, it is widely assumed that these memories lack detail. Contrary to this assumption, here we show that long-term memory is capable of storing a massive number of objects with details from the image. Participants viewed pictures of 2,500 objects over the course of 5.5 h. Afterward, they were shown pairs of images and indicated which of the two they had seen. The previously viewed item could be paired with either an object from a novel category, an object of the same basic-level category, or the same object in a different state or pose. Performance in each of these conditions was remarkably high (92%, 88%, and 87%, respectively), suggesting that participants successfully maintained detailed representations of thousands of images. These results have implications for cognitive models, in which capacity limitations impose a primary computational constraint (e.g., models of object recognition), and pose a challenge to neural models of memory storage and retrieval, which must be able to account for such a large and detailed storage capacity.

  20. Anaerobic Microbial Degradation of Hydrocarbons: From Enzymatic Reactions to the Environment.

    Science.gov (United States)

    Rabus, Ralf; Boll, Matthias; Heider, Johann; Meckenstock, Rainer U; Buckel, Wolfgang; Einsle, Oliver; Ermler, Ulrich; Golding, Bernard T; Gunsalus, Robert P; Kroneck, Peter M H; Krüger, Martin; Lueders, Tillmann; Martins, Berta M; Musat, Florin; Richnow, Hans H; Schink, Bernhard; Seifert, Jana; Szaleniec, Maciej; Treude, Tina; Ullmann, G Matthias; Vogt, Carsten; von Bergen, Martin; Wilkes, Heinz

    2016-01-01

    Hydrocarbons are abundant in anoxic environments and pose biochemical challenges to their anaerobic degradation by microorganisms. Within the framework of the Priority Program 1319, investigations funded by the Deutsche Forschungsgemeinschaft on the anaerobic microbial degradation of hydrocarbons ranged from isolation and enrichment of hitherto unknown hydrocarbon-degrading anaerobic microorganisms, discovery of novel reactions, detailed studies of enzyme mechanisms and structures to process-oriented in situ studies. Selected highlights from this program are collected in this synopsis, with more detailed information provided by theme-focused reviews of the special topic issue on 'Anaerobic biodegradation of hydrocarbons' [this issue, pp. 1-244]. The interdisciplinary character of the program, involving microbiologists, biochemists, organic chemists and environmental scientists, is best exemplified by the studies on alkyl-/arylalkylsuccinate synthases. Here, research topics ranged from in-depth mechanistic studies of archetypical toluene-activating benzylsuccinate synthase, substrate-specific phylogenetic clustering of alkyl-/arylalkylsuccinate synthases (toluene plus xylenes, p-cymene, p-cresol, 2-methylnaphthalene, n-alkanes), stereochemical and co-metabolic insights into n-alkane-activating (methylalkyl)succinate synthases to the discovery of bacterial groups previously unknown to possess alkyl-/arylalkylsuccinate synthases by means of functional gene markers and in situ field studies enabled by state-of-the-art stable isotope probing and fractionation approaches. Other topics are Mo-cofactor-dependent dehydrogenases performing O2-independent hydroxylation of hydrocarbons and alkyl side chains (ethylbenzene, p-cymene, cholesterol, n-hexadecane), degradation of p-alkylated benzoates and toluenes, glycyl radical-bearing 4-hydroxyphenylacetate decarboxylase, novel types of carboxylation reactions (for acetophenone, acetone, and potentially also benzene and

  1. Increasing organ donation rates by revealing recipient details to families of potential donors.

    Science.gov (United States)

    Shaw, David; Gardiner, Dale

    2018-02-01

    Many families refuse to consent to donation from their deceased relatives or over-rule the consent given before death by the patient, but giving families more information about the potential recipients of organs could reduce refusal rates. In this paper, we analyse arguments for and against doing so, and conclude that this strategy should be attempted. While it would be impractical and possibly unethical to give details of actual potential recipients, generic, realistic information about the people who could benefit from organs should be provided to families before they make a decision about donation or attempt to over-rule it. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  2. Reserving by detailed conditioning on individual claim

    Science.gov (United States)

    Kartikasari, Mujiati Dwi; Effendie, Adhitya Ronnie; Wilandari, Yuciana

    2017-03-01

    The estimation of claim reserves is an important activity in insurance companies to fulfill their liabilities. Recently, reserving method of individual claim have attracted a lot of interest in the actuarial science, which overcome some deficiency of aggregated claim method. This paper explores the Reserving by Detailed Conditioning (RDC) method using all of claim information for reserving with individual claim of liability insurance from an Indonesian general insurance company. Furthermore, we compare it to Chain Ladder and Bornhuetter-Ferguson method.

  3. Detail, Facture, and Colour in the Architecture of Polish Single-Family Houses after 1989

    Science.gov (United States)

    Sztafrowski, Marek

    2017-10-01

    The article presents single-family houses architecture transformations since 1989, with particularly close attention paid to the significance of detail, facture, and colour. The article presents the architecture as an art of designing and building facilities with both use and aesthetic value, an art of shaping space and building forms. Architectural work should correspond to the intended function, technique, economic and aesthetic requirements, thus shaping all elements of human immediate environment, both inside and outside of the building. Architecture of the building is perceived as form, structure, and function, as well as detail, facture, and colour. Facture and colour are created through materials used for external finishes. The solid of the building is noticed first while looking at the building, then the finishes detail such as colour, facture, and detail. Materials for external finishes are commonly selected for their aesthetic value equally with their technical characteristics. The detail was always a characteristic element of style. However, currently the fashion for details can be observed, the fashion for usage of materials for external finishes and inter-connected with that colour and facture. The architecture of Polish single-family houses underwent considerable metamorphosis after system change of 1989 - from destitute in form, devoid in detail and colour socmodernism, to architecture extremely varied in terms of form, utilised structures, materials, and detail. Hence, appearance of the phenomenon called fashion can be observed in the architecture, understood as constant changeability, seeking novelty, and creation based on opinion-forming centres. The architectural fashion consists of form, function, structure, building materials, detail, facture, and colour trends, e.g. after rejecting socmodernism, steep roofs characteristic for single-family houses trend started. After 1989, initially individual single-family house projects were created; however

  4. Effects of emotional context on memory for details: the role of attention.

    Science.gov (United States)

    Kim, Johann Sung-Cheul; Vossel, Gerhard; Gamer, Matthias

    2013-01-01

    It was repeatedly demonstrated that a negative emotional context enhances memory for central details while impairing memory for peripheral information. This trade-off effect is assumed to result from attentional processes: a negative context seems to narrow attention to central information at the expense of more peripheral details, thus causing the differential effects in memory. However, this explanation has rarely been tested and previous findings were partly inconclusive. For the present experiment 13 negative and 13 neutral naturalistic, thematically driven picture stories were constructed to test the trade-off effect in an ecologically more valid setting as compared to previous studies. During an incidental encoding phase, eye movements were recorded as an index of overt attention. In a subsequent recognition phase, memory for central and peripheral details occurring in the picture stories was tested. Explicit affective ratings and autonomic responses validated the induction of emotion during encoding. Consistent with the emotional trade-off effect on memory, encoding context differentially affected recognition of central and peripheral details. However, contrary to the common assumption, the emotional trade-off effect on memory was not mediated by attentional processes. By contrast, results suggest that the relevance of attentional processing for later recognition memory depends on the centrality of information and the emotional context but not their interaction. Thus, central information was remembered well even when fixated very briefly whereas memory for peripheral information depended more on overt attention at encoding. Moreover, the influence of overt attention on memory for central and peripheral details seems to be much lower for an arousing as compared to a neutral context.

  5. CMHC [Canada Mortgage and Housing Corporation] research project: Testing of air barrier construction details 2

    Energy Technology Data Exchange (ETDEWEB)

    1993-03-31

    Air leakage control through the building envelope of wood framed houses is more important than ever. This is because owners expect better temperature control, higher indoor humidity in winter, low energy consumption and building durability. The leakage of air is controlled by the air barrier system. There are several new technologies to construct an air barrier system for the building envelope. These are the Poly Approach, the Air Drywall Approach (ADA) and the EASE system. The development of these systems was undertaken primarily by the building community without significant research and development. While it is believed that these methods improve airtightness it is not known if the improvement is marginal or significant. A study was conducted to determine actual performace of several different types of construction details for each of the different approaches. Each of these details was designed and constructed using one of the air barrier methods and tested in the laboratory. The test details included sill plate, the partition wall, the stair stringer, the electrical outlets, the bathtub detail, the plumbing stack detail, the metal chimney detail, the bathroom fan detail and the EASE wall system. The test results revealed that the Poly, ADA and EASE approaches reduce air leakage by a factor of six, if applied with a modest degree of workmanship. Further, certain Poly details are to be reconsidered because they lack adequate support against design wind load pressures. 37 figs., 12 tabs.

  6. Using ecological zones to increase the detail of Landsat classifications

    Science.gov (United States)

    Fox, L., III; Mayer, K. E.

    1981-01-01

    Changes in classification detail of forest species descriptions were made for Landsat data on 2.2 million acres in northwestern California. Because basic forest canopy structures may exhibit very similar E-M energy reflectance patterns in different environmental regions, classification labels based on Landsat spectral signatures alone become very generalized when mapping large heterogeneous ecological regions. By adding a seven ecological zone stratification, a 167% improvement in classification detail was made over the results achieved without it. The seven zone stratification is a less costly alternative to the inclusion of complex collateral information, such as terrain data and soil type, into the Landsat data base when making inventories of areas greater than 500,000 acres.

  7. KNOW YOUR NEIGHBORHOOD: A DETAILED MODEL ATMOSPHERE ANALYSIS OF NEARBY WHITE DWARFS

    Energy Technology Data Exchange (ETDEWEB)

    Giammichele, N.; Bergeron, P. [Kitt Peak National Observatory, National Optical Astronomy Observatory, which is operated by the Association of Universities for Research in Astronomy (AURA) under cooperative agreement with the National Science Foundation (United States); Dufour, P., E-mail: noemi.giammichele@astro.umontreal.ca, E-mail: pierre.bergeron@astro.umontreal.ca, E-mail: patrick.dufour@astro.umontreal.ca [Departement de Physique, Universite de Montreal, C.P. 6128, Succ. Centre-Ville, Montreal, Quebec H3C 3J7 (Canada)

    2012-04-01

    We present improved atmospheric parameters of nearby white dwarfs lying within 20 pc of the Sun. The aim of the current study is to obtain the best statistical model of the least-biased sample of the white dwarf population. A homogeneous analysis of the local population is performed combining detailed spectroscopic and photometric analyses based on improved model atmosphere calculations for various spectral types including DA, DB, DC, DQ, and DZ stars. The spectroscopic technique is applied to all stars in our sample for which optical spectra are available. Photometric energy distributions, when available, are also combined to trigonometric parallax measurements to derive effective temperatures, stellar radii, as well as atmospheric compositions. A revised catalog of white dwarfs in the solar neighborhood is presented. We provide, for the first time, a comprehensive analysis of the mass distribution and the chemical distribution of white dwarf stars in a volume-limited sample.

  8. Routing the asteroid surface vehicle with detailed mechanics

    Science.gov (United States)

    Yu, Yang; Baoyin, He-Xi

    2014-06-01

    The motion of a surface vehicle on/above an irregular object is investigated for a potential interest in the insitu explorations to asteroids of the solar system. A global valid numeric method, including detailed gravity and geomorphology, is developed to mimic the behaviors of the test particles governed by the orbital equations and surface coupling effects. A general discussion on the surface mechanical environment of a specified asteroid, 1620 Geographos, is presented to make a global evaluation of the surface vehicle's working conditions. We show the connections between the natural trajectories near the ground and differential features of the asteroid surface, which describes both the good and bad of typical terrains from the viewpoint of vehicles' dynamic performances. Monte Carlo simulations are performed to take a further look at the trajectories of particles initializing near the surface. The simulations reveal consistent conclusions with the analysis, i.e., the open-field flat ground and slightly concave basins/valleys are the best choices for the vehicles' dynamical security. The dependence of decending trajectories on the releasing height is studied as an application; the results show that the pole direction (where the centrifugal force is zero) is the most stable direction in which the shift of a natural trajectory will be well limited after landing. We present this work as an example for pre-analysis that provides guidance to engineering design of the exploration site and routing the surface vehicles.

  9. The effect of giving detailed information about intravenous radiopharmaceutical administration on the anxiety level of patients who request more information

    International Nuclear Information System (INIS)

    Kaya, E.; Ciftci, I.; Demirel, R.; Gecici, O.; Cigerci, Y.

    2010-01-01

    Nuclear medicine procedures use radiopharmaceuticals, which produce radiation and potential adverse reactions, albeit at a low rate. It is the patient's ethical, legal, and medical right to be informed of the potential side effects of procedures applied to them. Our purpose was to determine the effect of providing information about intravenous radiopharmaceutical administration on the anxiety level of patients who request more information. This study was completed in two separate Nuclear Medicine Departments. The study included 620 (247 M, 373 F) patients who had been referred for myocardial perfusion, bone, dynamic renal, and thyroid scintigraphic examinations. The patients were divided into two groups according to whether they requested more information or not. Group 1 consisted of 388 patients who wanted to receive more information about the procedure, while Group 2 consisted of 232 patients who did not request additional information. The State-Trait Anxiety Inventory (STAI-S and STAI-T) was used to determine a patient's anxiety level. After simple information was given, state and trait anxiety levels were measured in both groups. We gave detailed information to the patients in Group 1 and then measured state anxiety again. Detailed information included an explanation of the radiopharmaceutical risk and probable side effects due to the scan procedure. There was no statistical difference between Groups 1 and 2 in STAI-T or STAI-S scores after simple information was given (p=0.741 and p=0.945, respectively). The mean value of STAI-S score was increased after the provision of detailed information and there was a statistically significant difference between after simple information STAI-S and after detailed information STAI-S (p<0.001). The STAI-S score was increased in 246 patients and decreased in 110 patients after detailed information, while there was no change in 32 patients. After detailed information, the greatest increase in STAI-S score was seen in the

  10. The Gut Microbiome Feelings of the Brain: A Perspective for Non-Microbiologists

    Directory of Open Access Journals (Sweden)

    Aaron Lerner

    2017-10-01

    Full Text Available Objectives: To comprehensively review the scientific knowledge on the gut–brain axis. Methods: Various publications on the gut–brain axis, until 31 July 2017, were screened using the Medline, Google, and Cochrane Library databases. The search was performed using the following keywords: “gut-brain axis”, “gut-microbiota-brain axis”, “nutrition microbiome/microbiota”, “enteric nervous system”, “enteric glial cells/network”, “gut-brain pathways”, “microbiome immune system”, “microbiome neuroendocrine system” and “intestinal/gut/enteric neuropeptides”. Relevant articles were selected and reviewed. Results: Tremendous progress has been made in exploring the interactions between nutrients, the microbiome, and the intestinal, epithelium–enteric nervous, endocrine and immune systems and the brain. The basis of the gut–brain axis comprises of an array of multichannel sensing and trafficking pathways that are suggested to convey the enteric signals to the brain. These are mediated by neuroanatomy (represented by the vagal and spinal afferent neurons, the neuroendocrine–hypothalamic–pituitary–adrenal (HPA axis (represented by the gut hormones, immune routes (represented by multiple cytokines, microbially-derived neurotransmitters, and finally the gate keepers of the intestinal and brain barriers. Their mutual and harmonious but intricate interaction is essential for human life and brain performance. However, a failure in the interaction leads to a number of inflammatory-, autoimmune-, neurodegenerative-, metabolic-, mood-, behavioral-, cognitive-, autism-spectrum-, stress- and pain-related disorders. The limited availability of information on the mechanisms, pathways and cause-and-effect relationships hinders us from translating and implementing the knowledge from the bench to the clinic. Implications: Further understanding of this intricate field might potentially shed light on novel preventive and therapeutic strategies to combat these disorders. Nutritional approaches, microbiome manipulations, enteric and brain barrier reinforcement and sensing and trafficking modulation might improve physical and mental health outcomes.

  11. Detailed modeling of superconducting magnetic energy storage (SMES) system

    NARCIS (Netherlands)

    Chen, L.; Liu, Y.; Arsoy, A.B.; Ribeiro, P.F.; Steurer, M.; Iravani, M.R.

    2006-01-01

    This paper presents a detailed model for simulation of a Superconducting Magnetic Energy Storage (SMES) system. SMES technology has the potential to bring real power storage characteristic to the utility transmission and distribution systems. The principle of SMES system operation is reviewed in

  12. EPA Enforcement and Compliance History Online: Water Effluent Charts Details

    Data.gov (United States)

    U.S. Environmental Protection Agency — Detailed Discharge Monitoring Report (DMR) data supporting effluent charts for one Clean Water Act discharge permit. Includes effluent parameters, amounts discharged...

  13. Multi-sparse dictionary colorization algorithm based on the feature classification and detail enhancement

    Science.gov (United States)

    Yan, Dan; Bai, Lianfa; Zhang, Yi; Han, Jing

    2018-02-01

    For the problems of missing details and performance of the colorization based on sparse representation, we propose a conceptual model framework for colorizing gray-scale images, and then a multi-sparse dictionary colorization algorithm based on the feature classification and detail enhancement (CEMDC) is proposed based on this framework. The algorithm can achieve a natural colorized effect for a gray-scale image, and it is consistent with the human vision. First, the algorithm establishes a multi-sparse dictionary classification colorization model. Then, to improve the accuracy rate of the classification, the corresponding local constraint algorithm is proposed. Finally, we propose a detail enhancement based on Laplacian Pyramid, which is effective in solving the problem of missing details and improving the speed of image colorization. In addition, the algorithm not only realizes the colorization of the visual gray-scale image, but also can be applied to the other areas, such as color transfer between color images, colorizing gray fusion images, and infrared images.

  14. Understanding the Anatomy of the Upper Face When Providing Aesthetic Injection Treatments.

    Science.gov (United States)

    Hotta, Tracey A

    2016-01-01

    Advanced rejuvenation procedures for the upper face are becoming increasingly popular for aesthetic providers but are considered a high-risk treatment area for dermal filler/contouring products. Risks may range from bruising, which is manageable, to blindness, most often irreversible. Detailed comprehension of the facial anatomy is imperative when performing aesthetic injections including neuromodulators and dermal filler/contouring products. Understanding the location and function of the muscles, as well as landmarking the blood vessels and nerves, will assist the aesthetic provider to perform safe, confident injection procedures. This article focuses on the upper face anatomy as identified by the author's cadaveric dissections and includes the treatment areas of the frontalis, temporalis, and glabellar complex. The author's next article for the Plastic Surgical Nursing journal will focus on the periorbital area.

  15. Numerical optimization of conical flow waveriders including detailed viscous effects

    Science.gov (United States)

    Bowcutt, Kevin G.; Anderson, John D., Jr.; Capriotti, Diego

    1987-01-01

    A family of optimized hypersonic waveriders is generated and studied wherein detailed viscous effects are included within the optimization process itself. This is in contrast to previous optimized waverider work, wherein purely inviscid flow is used to obtain the waverider shapes. For the present waveriders, the undersurface is a streamsurface of an inviscid conical flowfield, the upper surface is a streamsurface of the inviscid flow over a tapered cylinder (calculated by the axisymmetric method of characteristics), and the viscous effects are treated by integral solutions of the boundary layer equations. Transition from laminar to turbulent flow is included within the viscous calculations. The optimization is carried out using a nonlinear simplex method. The resulting family of viscous hypersonic waveriders yields predicted high values of lift/drag, high enough to break the L/D barrier based on experience with other hypersonic configurations. Moreover, the numerical optimization process for the viscous waveriders results in distinctly different shapes compared to previous work with inviscid-designed waveriders. Also, the fine details of the viscous solution, such as how the shear stress is distributed over the surface, and the location of transition, are crucial to the details of the resulting waverider geometry. Finally, the moment coefficient variations and heat transfer distributions associated with the viscous optimized waveriders are studied.

  16. Detailed description of an SSAC at the facility level for on-load refueled power reactor facilities

    International Nuclear Information System (INIS)

    Jones, R.J.

    1985-11-01

    The purpose of this document is to provide a detailed description of a system for the accounting for and control of nuclear material in an on-load refueled power reactor facility which can be used by a facility operator to establish his own system to comply with a national system for nuclear material accounting and control and to facilitate application of IAEA safeguards. The scope of this document is limited to descriptions of the following SSAC elements: (1) Nuclear Material Measurements; (2) Measurement Quality; (3) Records and Reports; (4) Physical Inventory Taking; (5) Material Balance Closing

  17. A Comprehensive Survey of Preclinical Microbiology Curricula Among US Medical Schools.

    Science.gov (United States)

    Melber, Dora J; Teherani, Arianne; Schwartz, Brian S

    2016-07-15

    A strong foundational understanding of microbiology is crucial for the 21st century physician. Given recent major advances in medical microbiology, curricular changes will likely be needed. Before transforming curricula, we must first obtain a comprehensive understanding of contemporary medical student microbiology education. We disseminated a 38-question survey to microbiology course directors and curriculum deans at 142 US medical schools accredited by the Liason Committee on Medical Education. Survey questions focused on course leadership, curricular structure, course content, and educator perceptions about microbiology education locally and nationally. One hundred and four (73%) of 142 schools completed the survey. Ninety-four (90%) schools identified a course director. Of these, 48% were led by microbiologists alone, 23% co-led by a microbiologist and a clinician, 20% by a clinician alone, and 8% by a laboratory medicine physician with or without a co-director. At 55 (53%) schools, the curricula were organized in a single block or course and at 47 (45%) it was integrated into other curricula. Areas of emerging importance, such as antimicrobial stewardship, global health, infection control, and the microbiome, were addressed at 66%, 65%, 64%, and 47% of institutions, respectively. Respondents reported the following concerns: challenges integrating microbiology into other courses, reduced total teaching hours, and difficulty balancing basic and clinical science topics. Preclinical microbiology course directors report significant challenges in meeting the needs of changing curriculum structure and content. Enhanced local collaboration between microbiologists and clinicians, as well as national collaboration among relevant societies to design best practices and support research, may be strategies for future success. © The Author 2016. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e

  18. It's in the details: The role of selective discussion in forgetting of children's autobiographical memories.

    Science.gov (United States)

    Glynn, Ruth; Salmon, Karen; Low, Jason

    2018-03-01

    This experiment investigated whether retrieval-induced forgetting (RIF) would be found in children's self-generated autobiographical memory recall. An adapted version of the RIF paradigm for adults' autobiographical memories was administered to 8- and 9-year-old children (N = 65). We hypothesized that RIF would be found in terms of both number of memories recalled and amount of memory detail reported. The relationship between memory detail at the retrieval practice phase and RIF magnitude was also investigated. Consistent with hypotheses, RIF was found for both the number of memories recalled and the amount of memory detail reported. In addition, memory detail at retrieval practice was associated with increased RIF magnitude. Findings extend the current literature in three ways. First, they indicate that selective discussion of autobiographical events with children can cause forgetting of similar non-discussed events. Second, even when these non-discussed events are recalled, they contain sparser memory detail. Finally, when events are selectively discussed in greater detail, forgetting of similar non-discussed events occurs to a greater extent. Copyright © 2017 Elsevier Inc. All rights reserved.

  19. Frequency and Therapeutic Outcomes of Culture Positive Invasive ...

    African Journals Online (AJOL)

    From May 2012 to July 2013, all cases from consults sent to the clinical microbiologists for review and patients with positive samples were identified from the mycology laboratory registers. Hospital based frequency of Invasive Fungal Infections was 42.5%. Patients' ages ranged from 5 days to 71 years with a median of 29 ...

  20. Public Health Implications of Cysticercosis Acquired in the United States

    Centers for Disease Control (CDC) Podcasts

    2011-01-06

    In this podcast, Dr. Patricia Wilkins, a research microbiologist at CDC, discusses an infection caused by the larvae of taenia solium, the pork tapeworm.  Created: 1/6/2011 by National Center for Emerging and Zoonotic Infectious Diseases (NCEZID); National Center for Immunization and Respiratory Diseases (NCIRD).   Date Released: 1/6/2011.

  1. Cryptosporidium Infections Among Children in Peru

    Centers for Disease Control (CDC) Podcasts

    Cryptosporidium is a waterborne bacteria that can cause severe diarrhea and vomiting. In this podcast, Dr. Vita Cama, CDC microbiologist, discusses an article in the October 2008 issue of Emerging Infectious Diseases. The paper examines Cryptosporidium infections among children in Peru, including the number of infections, symptoms experienced, and what species of Crypto were responsible.

  2. Automated leak localization performance without detailed demand distribution data

    NARCIS (Netherlands)

    Moors, Janneke; Scholten, L.; van der Hoek, J.P.; den Besten, J.

    2018-01-01

    Automatic leak localization has been suggested to reduce the time and personnel efforts needed to localize
    (small) leaks. Yet, the available methods require a detailed demand distribution model for successful
    calibration and good leak localization performance. The main aim of this work was

  3. In Situ Analysis of Bacterial Lipopeptide Antibiotics by Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging.

    Science.gov (United States)

    Debois, Delphine; Ongena, Marc; Cawoy, Hélène; De Pauw, Edwin

    2016-01-01

    Matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI MSI) is a technique developed in the late 1990s enabling the two-dimensional mapping of a broad variety of biomolecules present at the surface of a sample. In many applications including pharmaceutical studies or biomarker discovery, the distribution of proteins, lipids or drugs, and metabolites may be visualized within tissue sections. More recently, MALDI MSI has become increasingly applied in microbiology where the versatility of the technique is perfectly suited to monitor the metabolic dynamics of bacterial colonies. The work described here is focused on the application of MALDI MSI to map secondary metabolites produced by Bacilli, especially lipopeptides, produced by bacterial cells during their interaction with their environment (bacteria, fungi, plant roots, etc.). This chapter addresses the advantages and challenges that the implementation of MALDI MSI to microbiological samples entails, including detailed protocols on sample preparation (from both microbiologist and mass spectrometrist points of view), matrix deposition, and data acquisition and interpretation. Lipopeptide images recorded from confrontation plates are also presented.

  4. Detailed kinetic modeling study of n-pentanol oxidation

    KAUST Repository

    Heufer, Karl Alexander; Sarathy, Mani; Curran, Henry J.; Davis, Alexander C.; Westbrook, Charles K.; Pitz, William J.

    2012-01-01

    To help overcome the world's dependence upon fossil fuels, suitable biofuels are promising alternatives that can be used in the transportation sector. Recent research on internal combustion engines shows that short alcoholic fuels (e.g., ethanol or n-butanol) have reduced pollutant emissions and increased knock resistance compared to fossil fuels. Although higher molecular weight alcohols (e.g., n-pentanol and n-hexanol) exhibit higher reactivity that lowers their knock resistance, they are suitable for diesel engines or advanced engine concepts, such as homogeneous charge compression ignition (HCCI), where higher reactivity at lower temperatures is necessary for engine operation. The present study presents a detailed kinetic model for n-pentanol based on modeling rules previously presented for n-butanol. This approach was initially validated using quantum chemistry calculations to verify the most stable n-pentanol conformation and to obtain C-H and C-C bond dissociation energies. The proposed model has been validated against ignition delay time data, speciation data from a jet-stirred reactor, and laminar flame velocity measurements. Overall, the model shows good agreement with the experiments and permits a detailed discussion of the differences between alcohols and alkanes. © 2012 American Chemical Society.

  5. Detailed kinetic modeling study of n-pentanol oxidation

    KAUST Repository

    Heufer, Karl Alexander

    2012-10-18

    To help overcome the world\\'s dependence upon fossil fuels, suitable biofuels are promising alternatives that can be used in the transportation sector. Recent research on internal combustion engines shows that short alcoholic fuels (e.g., ethanol or n-butanol) have reduced pollutant emissions and increased knock resistance compared to fossil fuels. Although higher molecular weight alcohols (e.g., n-pentanol and n-hexanol) exhibit higher reactivity that lowers their knock resistance, they are suitable for diesel engines or advanced engine concepts, such as homogeneous charge compression ignition (HCCI), where higher reactivity at lower temperatures is necessary for engine operation. The present study presents a detailed kinetic model for n-pentanol based on modeling rules previously presented for n-butanol. This approach was initially validated using quantum chemistry calculations to verify the most stable n-pentanol conformation and to obtain C-H and C-C bond dissociation energies. The proposed model has been validated against ignition delay time data, speciation data from a jet-stirred reactor, and laminar flame velocity measurements. Overall, the model shows good agreement with the experiments and permits a detailed discussion of the differences between alcohols and alkanes. © 2012 American Chemical Society.

  6. Corridor consultations and the medical microbiological record: is patient safety at risk?

    Science.gov (United States)

    Heard, S R; Roberts, C; Furrows, S J; Kelsey, M; Southgate, L

    2003-01-01

    The performance procedures of the General Medical Council are aimed at identifying seriously deficient performance in a doctor. The performance procedures require the medical record to be of a standard that enables the next doctor seeing the patient to give adequate care based on the available information. Setting standards for microbiological record keeping has proved difficult. Over one fifth of practising medical microbiologists (including virologists) in the UK (139 of 676) responded to a survey undertaken by the working group developing the performance procedures for microbiology, to identify current practice and to develop recommendations for agreement within the profession about the standards of the microbiological record. The cumulative frequency for the surveyed recording methods used indicated that at various times 65% (90 of 139) of respondents used a daybook, 62% (86 of 139) used the back of the clinical request card, 57% (79 of 139) used a computer record, and 22% (30 of 139) used an index card system to record microbiological advice, suggesting wide variability in relation to how medical microbiologists maintain clinical records. PMID:12499432

  7. Multi -omics and metabolic modelling pipelines: challenges and tools for systems microbiology.

    Science.gov (United States)

    Fondi, Marco; Liò, Pietro

    2015-02-01

    Integrated -omics approaches are quickly spreading across microbiology research labs, leading to (i) the possibility of detecting previously hidden features of microbial cells like multi-scale spatial organization and (ii) tracing molecular components across multiple cellular functional states. This promises to reduce the knowledge gap between genotype and phenotype and poses new challenges for computational microbiologists. We underline how the capability to unravel the complexity of microbial life will strongly depend on the integration of the huge and diverse amount of information that can be derived today from -omics experiments. In this work, we present opportunities and challenges of multi -omics data integration in current systems biology pipelines. We here discuss which layers of biological information are important for biotechnological and clinical purposes, with a special focus on bacterial metabolism and modelling procedures. A general review of the most recent computational tools for performing large-scale datasets integration is also presented, together with a possible framework to guide the design of systems biology experiments by microbiologists. Copyright © 2015. Published by Elsevier GmbH.

  8. Integration of microbiological, epidemiological and next generation sequencing technologies data for the managing of nosocomial infections

    Directory of Open Access Journals (Sweden)

    Matteo Brilli

    2018-02-01

    Full Text Available At its core, the work of clinical microbiologists consists in the retrieving of a few bytes of information (species identification; metabolic capacities; staining and antigenic properties; antibiotic resistance profiles, etc. from pathogenic agents. The development of next generation sequencing technologies (NGS, and the possibility to determine the entire genome for bacterial pathogens, fungi and protozoans will likely introduce a breakthrough in the amount of information generated by clinical microbiology laboratories: from bytes to Megabytes of information, for a single isolate. In parallel, the development of novel informatics tools, designed for the management and analysis of the so-called Big Data, offers the possibility to search for patterns in databases collecting genomic and microbiological information on the pathogens, as well as epidemiological data and information on the clinical parameters of the patients. Nosocomial infections and antibiotic resistance will likely represent major challenges for clinical microbiologists, in the next decades. In this paper, we describe how bacterial genomics based on NGS, integrated with novel informatic tools, could contribute to the control of hospital infections and multi-drug resistant pathogens.

  9. [Respiratory infections caused by slow-growing bacteria: Nocardia, Actinomyces, Rhodococcus].

    Science.gov (United States)

    Eschapasse, E; Hussenet, C; Bergeron, A; Lebeaux, D

    2017-06-01

    Pneumonia caused by slow-growing bacteria is rare but sometimes severe. These infections share many similarities such as several differential diagnoses, difficulties to identify the pathogen, the importance of involving the microbiologist in the diagnostic investigation and the need for prolonged antibiotic treatment. However, major differences distinguish them: Nocardia and Rhodococcus infect mainly immunocompromised patients while actinomycosis also concerns immunocompetent patients; the severity of nocardioses is related to their hematogenous spread while locoregional extension by contiguity makes the gravity of actinomycosis. For these diseases, molecular diagnostic tools are essential, either to obtain a species identification and guide treatment in the case of nocardiosis or to confirm the diagnosis from a biological sample. Treatment of these infections is complex due to: (1) the limited data in the literature; (2) the need for prolonged treatment of several months; (3) the management of toxicities and drug interactions for the treatment of Nocardia and Rhodococcus. Close cooperation between pneumonologists, infectious disease specialists and microbiologists is essential for the management of these patients. Copyright © 2017 SPLF. Published by Elsevier Masson SAS. All rights reserved.

  10. Ocean Observing at Axial Seamount: Details of the Current OOI-RSN Design Within the Context of the April 2011 Eruption

    Science.gov (United States)

    Proskurowski, G.; Kelley, D. S.; Fundis, A. T.; Kawka, O.; Denny, G. F.; Delaney, J. R.

    2011-12-01

    In 2013, the NSF's Ocean Observatories Initiative (OOI) will deploy 22 instrument suites within the caldera of Axial Seamount as part of the cabled observatory component implemented by the Regional Scale Nodes (RSN) at the University of Washington. The cabled infrastructure will initially provide Axial caldera with a total of 8kW of power and 11Gbps of data bandwidth. Only an approximate 20% fraction will be used by "core instrumentation"-instrumentation supported and maintained by OOI-RSN. Thus, the OOI provided infrastructure is highly, and readily, expandable to include community-generated instrumention once the system is commissioned and begins operations in early 2015. Here we present the details of the current design of the cabled observatory at Axial Seamount, including locations of instruments, data products, and sampling rates placed in the context of meter scale resolution bathymetry and down-looking photomosaics of the experimental sites. The April 2011 Axial eruption is a demonstration of the importance of transmitting seismic, video, and vent fluid chemistry information in real-time. The eruptive event, or series of events, in April 2011 went undetected until a series of ROV/AUV cruises, planned separately and years in advance, made observations to discover, confirm, and detail the transformation to Axial (see Chadwick et al., this session). What transpired during, and shortly after, the eruption will remain largely unknown, as the initial extraordinary fluxes of heat, chemistry and biology will have decayed in the intervening three and a half months. Here we detail the response capabilities of the OOI-RSN cabled observatory to a future eruptive event under two scenarios-as built, and an expanded version using existing technology.

  11. Imaging by Electrochemical Scanning Tunneling Microscopy and Deconvolution Resolving More Details of Surfaces Nanomorphology

    DEFF Research Database (Denmark)

    Andersen, Jens Enevold Thaulov

    observed in high-resolution images of metallic nanocrystallites may be effectively deconvoluted, as to resolve more details of the crystalline morphology (see figure). Images of surface-crystalline metals indicate that more than a single atomic layer is involved in mediating the tunneling current......Upon imaging, electrochemical scanning tunneling microscopy (ESTM), scanning electrochemical micro-scopy (SECM) and in situ STM resolve information on electronic structures and on surface topography. At very high resolution, imaging processing is required, as to obtain information that relates...... to crystallographic-surface structures. Within the wide range of new technologies, those images surface features, the electrochemical scanning tunneling microscope (ESTM) provides means of atomic resolution where the tip participates actively in the process of imaging. Two metallic surfaces influence ions trapped...

  12. Detailed thermal-hydraulic computation into a containment building

    Energy Technology Data Exchange (ETDEWEB)

    Caruso. A.; Flour, I.; Simonin, O. [EDF/LNH, Chatou (France); Cherbonnel, C [EDF/SEPTEN, Villeurbanne (France)

    1995-09-01

    This paper deals with numerical predictions of the influence of water sprays upon stratifications into a containment building using a two-dimensional two-phase flow code. Basic equations and closure assumptions are briefly presented. A test case in a situation involving spray evaporation is first detailed to illustrate the validation step. Then results are presented for a compressible recirculating flow into a containment building with condensation phenomena.

  13. A detailed family history of myocardial infarction and risk of myocardial infarction

    DEFF Research Database (Denmark)

    Ranthe, Mattis Flyvholm; Petersen, Jonathan Aavang; Bundgård, Henning

    2015-01-01

    of cardiovascular medications. CONCLUSION: A detailed family history, particularly number of affected first- and second-degree relatives, contributes meaningfully to risk assessment, especially in middle-aged persons. Future studies should test for potential improvement of risk algorithm prediction using detailed......BACKGROUND: Family history of myocardial infarction (MI) is an independent risk factor for MI. Several genetic variants are associated with increased risk of MI and family history of MI in a first-degree relative doubles MI risk. However, although family history of MI is not a simple dichotomous...... risk factor, the impact of specific, detailed family histories has not received much attention, despite its high clinical relevance. We examined risk of MI by MIs in first- and second-degree relatives and by number and age of affected relatives. METHODS AND FINDINGS: Using Danish national registers, we...

  14. Detailed Balance of Thermalization Dynamics in Rydberg-Atom Quantum Simulators.

    Science.gov (United States)

    Kim, Hyosub; Park, YeJe; Kim, Kyungtae; Sim, H-S; Ahn, Jaewook

    2018-05-04

    Dynamics of large complex systems, such as relaxation towards equilibrium in classical statistical mechanics, often obeys a master equation that captures essential information from the complexities. Here, we find that thermalization of an isolated many-body quantum state can be described by a master equation. We observe sudden quench dynamics of quantum Ising-like models implemented in our quantum simulator, defect-free single-atom tweezers in conjunction with Rydberg-atom interaction. Saturation of their local observables, a thermalization signature, obeys a master equation experimentally constructed by monitoring the occupation probabilities of prequench states and imposing the principle of the detailed balance. Our experiment agrees with theories and demonstrates the detailed balance in a thermalization dynamics that does not require coupling to baths or postulated randomness.

  15. Detailed Balance of Thermalization Dynamics in Rydberg-Atom Quantum Simulators

    Science.gov (United States)

    Kim, Hyosub; Park, YeJe; Kim, Kyungtae; Sim, H.-S.; Ahn, Jaewook

    2018-05-01

    Dynamics of large complex systems, such as relaxation towards equilibrium in classical statistical mechanics, often obeys a master equation that captures essential information from the complexities. Here, we find that thermalization of an isolated many-body quantum state can be described by a master equation. We observe sudden quench dynamics of quantum Ising-like models implemented in our quantum simulator, defect-free single-atom tweezers in conjunction with Rydberg-atom interaction. Saturation of their local observables, a thermalization signature, obeys a master equation experimentally constructed by monitoring the occupation probabilities of prequench states and imposing the principle of the detailed balance. Our experiment agrees with theories and demonstrates the detailed balance in a thermalization dynamics that does not require coupling to baths or postulated randomness.

  16. Victory Has a Thousand Fathers: Detailed Counterinsurgency Case Studies

    Science.gov (United States)

    2010-01-01

    Fathers: Detailed Counterinsurgency Case Studies There was more progress toward a peace agreement in 1999 when Nelson Mandela was designated as...mediator for the conflict. While Mandela still failed to bring the rebel groups to the table, he was able to negotiate an agreement among the political

  17. Detailed Structural Analyses of KOH Activated Carbon from Waste Coffee Beans

    Science.gov (United States)

    Takahata, Tomokazu; Toda, Ikumi; Ono, Hiroki; Ohshio, Shigeo; Akasaka, Hiroki; Himeno, Syuji; Kokubu, Toshinori; Saitoh, Hidetoshi

    2009-11-01

    The relationship of the detailed structural change of KOH activated carbon and hydrogen storage ability was investigated in activated carbon materials fabricated from waste coffee beans. The specific surface area of porous carbon materials calculated from N2 adsorption isotherms stood at 2070 m2/g when the weight ratio of KOH to carbon materials was 5:1, and pore size was in the range of approximately 0.6 to 1.1 nm as micropores. In the structural analysis, X-ray diffraction analysis and Raman spectroscopy indicated structural change in these carbon materials through KOH activation. The order of the graphite structure changed to a smaller scale with this activation. It is theorized that specific surface area increased using micropores provided by carbon materials developed from the descent of the graphite structure. Hydrogen storage ability improved with these structural changes, and reached 0.6 wt % at 2070 m2/g. These results suggest that hydrogen storage ability is conferred by the chemical effect on graphite of carbon materials.

  18. Poor methodological detail precludes experimental repeatability and hampers synthesis in ecology.

    Science.gov (United States)

    Haddaway, Neal R; Verhoeven, Jos T A

    2015-10-01

    Despite the scientific method's central tenets of reproducibility (the ability to obtain similar results when repeated) and repeatability (the ability to replicate an experiment based on methods described), published ecological research continues to fail to provide sufficient methodological detail to allow either repeatability of verification. Recent systematic reviews highlight the problem, with one example demonstrating that an average of 13% of studies per year (±8.0 [SD]) failed to report sample sizes. The problem affects the ability to verify the accuracy of any analysis, to repeat methods used, and to assimilate the study findings into powerful and useful meta-analyses. The problem is common in a variety of ecological topics examined to date, and despite previous calls for improved reporting and metadata archiving, which could indirectly alleviate the problem, there is no indication of an improvement in reporting standards over time. Here, we call on authors, editors, and peer reviewers to consider repeatability as a top priority when evaluating research manuscripts, bearing in mind that legacy and integration into the evidence base can drastically improve the impact of individual research reports.

  19. Detailed analysis of polybrominated biphenyl congeners in bird eggs from Norway

    International Nuclear Information System (INIS)

    Vetter, Walter; Recke, Roland von der; Herzke, Dorte; Nygard, Torgeir

    2008-01-01

    Individual eggs of six species of birds from Norway representing different food chains were analysed for residues of polybrominated biphenyls (PBBs). In all species, the residue pattern was dominated by hexaBBs. The dominating congeners were PBB 153, PBB 154, and PBB 155. Whereas PBB 153 is present in technical hexabromobiphenyl, PBB 154 and PBB 155 are formed by the reductive debromination of decabromobiphenyl. This was evidenced by the detection of several heptaBBs and octaBBs all of which are typical degradation intermediates of PBB 209. Hepta- and octaBBs were more than one order of magnitude less abundant than the hexaBBs. The second most prevailing homologue group was pentaBBs. The most relevant pentabrominated isomers were PBB 99 and PBB 101. Concentrations of the three hexaBBs - PBB 153, PBB 154, and PBB 155 - amounted to 1.3-13 ng/g wet weight or 3-23% of the contamination with polybrominated diphenyl ethers. - We provide for the first time detailed information on the PBB congeners present in eggs of bird of prey, and quantified three hexabromo congeners

  20. Towards a common disability assessment framework: theoretical and methodological issues for providing public services and benefits using ICF.

    Science.gov (United States)

    Francescutti, Carlo; Frattura, Lucilla; Troiano, Raffaella; Gongolo, Francesco; Martinuzzi, Andrea; Sala, Marina; Meucci, Paolo; Raggi, Alberto; Russo, Emanuela; Buffoni, Mara; Gorini, Giovanna; Conclave, Mario; Petrangeli, Agostino; Solipaca, Alessandro; Leonardi, Matilde

    2009-01-01

    To report on the preliminary results of an Italian project on the implementation of an ICF-based protocol for providing public services and benefits for persons with disabilities. The UN Convention on the Rights of persons with disabilities (UNC) was mapped to the ICF, and core elements were implemented in an ICF-based evaluation protocol. A person-environment interaction classification (PEIC) tree was also developed for defining evaluation outputs. The PEIC and the ICF-based protocol are the guideline and the data interpretation source, respectively, for providing public services and benefits. They enable to assign persons to different services, from surveillance and monitoring to facilitator provision or sustain over time, to barrier removal or to the reorganisation of environmental factors provision. A detailed description of the target intervention is made available through the implementation of a protocol, which points out the effect of personal support and other environmental factors. The detailed description of functioning and disability provided by our methodology can help policy makers and administrators in decision making, on the basis of a description of real needs, and in targeting person-tailored interventions.