WorldWideScience

Sample records for mic recovery medium

  1. Adsorption of anionic surfactants in limestone medium during oil recovery

    Energy Technology Data Exchange (ETDEWEB)

    Canbolat, Serhat; Bagci, Suat [Middle East Technical Univ., Dept. of Petroleum and Natural Gas Engineering, Ankara (Turkey)

    2004-07-15

    Foam-forming surfactant performance was evaluated by several experimental methods (interfacial tension, foam stability, corefloods) using commercial surfactants. There is considerable interest in the use of foam-forming surfactants for mobility control in water flood. To provide effective mobility control, the injected surfactant must propagate from the injection well toward the production well. One of the important parameters affecting propagation of foam-forming surfactant through the reservoir is the retention of surfactant due to its adsorption on reservoir rock. The determination of the adsorption of foam-forming surfactants in limestone reservoirs is important for the residual oil recovery efficiency. Adsorption measurements, recovery efficiencies, and surfactant and alkaline flooding experiments carried out with the representative of the selected surfactants alkaline solutions, linear alkyl benzene sulphonic acid (LABSA), sodium lauryl ether sulfate (SLES), and NaOH in a limestone medium. These surfactants were selected with respect to their foaming ability. Calibration curves formed by pH measurements were used to determine the correct adsorption amount of the used surfactants and recovery efficiency of these surfactants compared with base waterflooding. The results showed that LABSA adsorbed more than SLES in limestone reservoirs. The recovery efficiency of SLES was higher than the recovery efficiency of LABSA, and they decreased the recovery efficiency with respect to only the water injection case. (Author)

  2. MDS MIC Catalog Inputs

    Science.gov (United States)

    Johnson-Throop, Kathy A.; Vowell, C. W.; Smith, Byron; Darcy, Jeannette

    2006-01-01

    This viewgraph presentation reviews the inputs to the MDS Medical Information Communique (MIC) catalog. The purpose of the group is to provide input for updating the MDS MIC Catalog and to request that MMOP assign Action Item to other working groups and FSs to support the MITWG Process for developing MIC-DDs.

  3. Combustion for Enhanced Recovery of Light Oil at Medium Pressures

    NARCIS (Netherlands)

    Khoshnevis Gargar, N.

    2014-01-01

    Using conventional production methods, recovery percentages from oil reservoirs range from 5% for difficult oil to 50% for light oil in highly permeable homogeneous reservoirs. To increase the oil recovery factor, enhanced oil recovery (EOR) methods are used. We distinguish EOR that uses chemical

  4. Microorganisms involved in MIC

    Energy Technology Data Exchange (ETDEWEB)

    Sorensen, K. [Danish Technological Institute (Denmark)

    2011-07-01

    Microbiologically influenced corrosion (MIC) is a widespread problem that is difficult to detect and assess because of its complex mechanism. This paper presents the involvement of microorganisms in MIC. Some of the mechanisms that cause MIC include hydrogen consumption, production of acids, anode-cathode formation and electron shuttling. A classic bio-corrosive microorganism in the oil and gas industry is sulphate-reducing prokaryotes (SRP). Methanogens also increase corrosion rates in metals. Some of the phylogenetic orders detected while studying SRP and methanogens are archaeoglobales, clostridiales, methanosarcinales and methanothermococcus. There were some implications, such as growth of SRP not being correlated with growth of methanogens; methanogens were included in MIC risk assessment. A few examples are used to display how microorganisms are involved in topside corrosion and microbial community in producing wells. From the study, it can be concluded that, MIC risk assessment includes system data and empirical knowledge of the distribution and number of microorganisms in the system.

  5. Growing interest in MIC

    International Nuclear Information System (INIS)

    Crum, J.R.; Little, B.J.

    1991-01-01

    Although corrosion has not caused a major nuclear accident, it has resulted in degraded nuclear systems and components, unscheduled shut-downs and loss of productivity. From 1981 to 1988, operating and maintenance costs for nuclear plants more than doubled, while plant capacity increased by only 10%. And as nuclear plants age, service water system problems cause losses in capacity. Many corrosion failures in these systems cannot be understood, controlled or prevented using theories based on classic, abiotic corrosion mechanisms. But research has now identified microbiologically influenced corrosion (MIC - corrosion caused by the presence and activities of micro-organisms within biofilms on metals surfaces) as the cause of otherwise unexplained corrosion failures. Some prevention and control measures are examined. (author)

  6. Dataset on experimental investigation of gum arabic coated alumina nanoparticles for enhanced recovery of nigerian medium crude oil.

    Science.gov (United States)

    Orodu, Oyinkepreye D; Orodu, Kale B; Afolabi, Richard O; Dafe, Eboh A

    2018-08-01

    The dataset in this article are related to an experimental Enhanced Oil Recovery (EOR) scheme involving the use of dispersions containing Gum Arabic coated Alumina Nanoparticles (GCNPs) for Nigerian medium crude oil. The result contained in the dataset showed a 7.18% (5 wt% GCNPs), 7.81% (5 wt% GCNPs), and 5.61% (3 wt% GCNPs) improvement in the recovery oil beyond the water flooding stage for core samples A, B, and C respectively. Also, the improvement in recovery of the medium crude oil by the GCNPs dispersions when compared to Gum Arabic polymer flooding was evident in the dataset.

  7. Medium factors on anaerobic production of rhamnolipids by Pseudomonas aeruginosa SG and a simplifying medium for in situ microbial enhanced oil recovery applications.

    Science.gov (United States)

    Zhao, Feng; Zhou, Jidong; Han, Siqin; Ma, Fang; Zhang, Ying; Zhang, Jie

    2016-04-01

    Aerobic production of rhamnolipid by Pseudomonas aeruginosa was extensively studied. But effect of medium composition on anaerobic production of rhamnolipid by P. aeruginosa was unknown. A simplifying medium facilitating anaerobic production of rhamnolipid is urgently needed for in situ microbial enhanced oil recovery (MEOR). Medium factors affecting anaerobic production of rhamnolipid were investigated using P. aeruginosa SG (Genbank accession number KJ995745). Medium composition for anaerobic production of rhamnolipid by P. aeruginosa is different from that for aerobic production of rhamnolipid. Both hydrophobic substrate and organic nitrogen inhibited rhamnolipid production under anaerobic conditions. Glycerol and nitrate were the best carbon and nitrogen source. The commonly used N limitation under aerobic conditions was not conducive to rhamnolipid production under anaerobic conditions because the initial cell growth demanded enough nitrate for anaerobic respiration. But rhamnolipid was also fast accumulated under nitrogen starvation conditions. Sufficient phosphate was needed for anaerobic production of rhamnolipid. SO4(2-) and Mg(2+) are required for anaerobic production of rhamnolipid. Results will contribute to isolation bacteria strains which can anaerobically produce rhamnolipid and medium optimization for anaerobic production of rhamnolipid. Based on medium optimization by response surface methodology and ions composition of reservoir formation water, a simplifying medium containing 70.3 g/l glycerol, 5.25 g/l NaNO3, 5.49 g/l KH2PO4, 6.9 g/l K2HPO4·3H2O and 0.40 g/l MgSO4 was designed. Using the simplifying medium, 630 mg/l of rhamnolipid was produced by SG, and the anaerobic culture emulsified crude oil to EI24 = 82.5 %. The simplifying medium was promising for in situ MEOR applications.

  8. ECONOMIC POTENTIAL RECOVERY – A EUROPEAN CHALLENGE IN THE MEDIUM TERM

    Directory of Open Access Journals (Sweden)

    Rãdulescu Andrei

    2012-12-01

    Full Text Available The waves of the worst global financial and economic crisis since World War II have seriously affected the economy of the Euro Area. The first wave of the global crisis determined the worst recession in decades for the member states of the region. At present, the Monetary Union is confronted with the second wave of the crisis – the public debt problem. Despite the efforts adopted and implemented by the European policymakers over the past quarters, the sovereign debt crisis is far from over. Spain has recently become the “favourite target” of the financial markets. Among the consequences of the waves of the crisis for the Euro Area one can mention the potential output decline and the economic divergence (asymmetric evolution of member countries. In this context, the potential output recovery and the relaunch of the real economic convergence process represent the main challenges for the policymakers in the medium run. This paper analyses the evolution of potential GDP of the member countries of European Monetary Union (12. I employ the Hodrick-Prescott methodology on data from the World Bank Database. According to the results, the economic potential of the member states of the Euro Area (12 decreased to the lowest level of the past decades. At the same time, the analysis presents the differences exiting across the member states in terms of potential output. Some countries suffered an important potential output loss over the past quarters (it seems that Greece and Portugal have become asymmetric shocks in the Monetary Union. For these countries, the first wave of the global crisis transformed in a permanent shock. The decline of investments and the depreciation of human capital over the past quarters express a huge probability that potential output is going to maintain at a low level in the Euro Area over the following years. The recovery of potential GDP towards the pre-crisis levels is dependent on a higher participation rate

  9. The frequent occurrence of MIC

    Energy Technology Data Exchange (ETDEWEB)

    Graff, Matthias [Gesellschaft fuer Technische Mikrobiologie und Hygieneueberwachung - Dr. Graff und Partner, Stadtweg 9, D-38176 Wendeburg (Germany); Neubert, Volkmar [Institut fuer Materialpruefung und Werkstofftechnik Dr. Doelling und Dr. Neubert GmbH, Freiberger Strasse 1, D-38678 Clausthal-Zellerfeld (Germany)

    2004-07-01

    Microbial induced corrosion (MIC) is not as rare as many materials scientist and corrosion practitioners do believe. It is not an exotic and scarce event, but can be found frequently in many fields of corrosion research, provided that it is looked for. The reason for the relatively few descriptions of MIC cases seems to be the fact, that the microbiological approach is not widely known and applied in the world of materials science. MIC is not so much a corrosion mechanism on its own, but it enhances the corrosion rates of the 'normal' mechanisms to such an extent, that in some cases 'incredible' fast corrosion progress can be observed. The reason is the microorganisms' function as bio-catalysts: Chemical reactions, which are very slow under normal chemical conditions can be highly accelerated by living organisms. Besides that, several microorganisms do produce very corrosive substances which in natural environments do not occur without the activity of microorganisms, e. g. sulfuric or nitric acid. We want to point out, that it can be very worthy to take microbial induced corrosion into account. MIC is not the general answer for all unsolved corrosion problems, but to think about it helps in many corrosion cases as the authors had to experience. The initial indication for the presence of MIC are markedly increased corrosion rates. In the following, some of our 'lessons' are presented as short case studies: Two of them deal with steel corrosion characterized by increased corrosion rates. The third example presents corrosion damage of aluminium structures, where from a technical point of view corrosion was not expected, least of all microbial induced corrosion. (authors)

  10. Experiences on MIC monitoring by electrochemical techniques

    DEFF Research Database (Denmark)

    Cristiani, P.; Perboni, G.; Hilbert, Lisbeth Rischel

    2002-01-01

    Some results of practical experiences on the performances of electrochemical and electric MIC monitoring techniques, coming from the discussion in the Brite-Euram thematic network "MIC of industrial materials", are presented in this paper.......Some results of practical experiences on the performances of electrochemical and electric MIC monitoring techniques, coming from the discussion in the Brite-Euram thematic network "MIC of industrial materials", are presented in this paper....

  11. Colony formation by sublethally heat-injured Zygosaccharomyces rouxii as affected by solutes in the recovery medium and procedure for sterilizing medium.

    Science.gov (United States)

    Golden, D A; Beuchat, L R

    1990-01-01

    Recovery and colony formation by healthy and sublethally heat-injured cells of Zygosaccharomyces rouxii as influenced by the procedure for sterilizing recovery media (YM agar [YMA], wort agar, cornmeal agar, and oatmeal agar) were investigated. Media were supplemented with various concentrations of glucose, sucrose, glycerol, or sorbitol and sterilized by autoclaving (110 degrees C, 15 min) and by repeated treatment with steam (100 degrees C). An increase in sensitivity was observed when heat-injured cells were plated on glucose-supplemented YMA at an aw of 0.880 compared with aws of 0.933 and 0.998. Colonies which developed from unheated and heated cells on YMA at aws of 0.998 and 0.933 generally exceeded 0.5 mm in diameter within 3.5 to 4 days of incubation at 25 degrees C, whereas colonies formed on YMA at an aw of 0.880 typically did not exceed 0.5 mm in diameter until after 5.5 to 6.5 days of incubation. The number of colonies exceeding 0.5 mm in diameter which were formed by heat-injured cells on YMA at an aw of 0.880 was 2 to 3 logs less than the total number of colonies detected, i.e., on YMA at an aw of 0.933 and using no limits of exclusion based on colony diameter. A substantial portion of cells which survived heat treatment were sublethally injured as evidenced by increased sensitivity to a suboptimum aw (0.880). In no instance was recovery of Z. rouxii significantly affected by medium sterilization procedure when glucose or sorbitol was used as the aw-suppressing solute.(ABSTRACT TRUNCATED AT 250 WORDS) PMID:2403251

  12. Colony formation by sublethally heat-injured Zygosaccharomyces rouxii as affected by solutes in the recovery medium and procedure for sterilizing medium.

    Science.gov (United States)

    Golden, D A; Beuchat, L R

    1990-08-01

    Recovery and colony formation by healthy and sublethally heat-injured cells of Zygosaccharomyces rouxii as influenced by the procedure for sterilizing recovery media (YM agar [YMA], wort agar, cornmeal agar, and oatmeal agar) were investigated. Media were supplemented with various concentrations of glucose, sucrose, glycerol, or sorbitol and sterilized by autoclaving (110 degrees C, 15 min) and by repeated treatment with steam (100 degrees C). An increase in sensitivity was observed when heat-injured cells were plated on glucose-supplemented YMA at an aw of 0.880 compared with aws of 0.933 and 0.998. Colonies which developed from unheated and heated cells on YMA at aws of 0.998 and 0.933 generally exceeded 0.5 mm in diameter within 3.5 to 4 days of incubation at 25 degrees C, whereas colonies formed on YMA at an aw of 0.880 typically did not exceed 0.5 mm in diameter until after 5.5 to 6.5 days of incubation. The number of colonies exceeding 0.5 mm in diameter which were formed by heat-injured cells on YMA at an aw of 0.880 was 2 to 3 logs less than the total number of colonies detected, i.e., on YMA at an aw of 0.933 and using no limits of exclusion based on colony diameter. A substantial portion of cells which survived heat treatment were sublethally injured as evidenced by increased sensitivity to a suboptimum aw (0.880). In no instance was recovery of Z. rouxii significantly affected by medium sterilization procedure when glucose or sorbitol was used as the aw-suppressing solute.(ABSTRACT TRUNCATED AT 250 WORDS)

  13. Tree legumes in medium-term fallows: Nz fixation, nitrate recovery ...

    African Journals Online (AJOL)

    Legume effects on the fixation of atmospheric N and nitrate recovery were determined in a sub-humid, bi-modal rainfall system. Fallows improved with sesbania (Sesbania sesban) and tephrosia (Tephrosia vogellii) produced more biomass and fixed more N than those fallows improved with pigeonpea (Cajanus cajan) or ...

  14. Use of a primary isolation medium for recovery of methicillin-resistant Staphylococcus aureus.

    OpenAIRE

    Van Enk, R A; Thompson, K D

    1992-01-01

    Clinical specimens frequently contain methicillin-resistant Staphylococcus aureus (MRSA) isolates in low numbers or mixed with methicillin-susceptible staphylococci, which can obscure MRSA on nonselective media. By using an oxacillin-containing mannitol-salt-based selective and differential medium on 936 respiratory specimens, we recovered 45% more MRSA isolates (29 versus 20) than on nonselective media alone.

  15. Recovery of copper(II) and chromium(III) from nitrate medium with ...

    African Journals Online (AJOL)

    The solvent extraction of copper(II) and chromium(III) from nitrate medium with salicylideneaniline (HL) is studied as a function of various parameters: pH, concentration of salicylideneaniline, contact time and the nature of anoin (nitrate and sulfate) in aqueous phase. Chromium(III) is not extracted by salicylideneaniline ...

  16. Localized Intrathecal Delivery of Mesenchymal Stromal Cells Conditioned Medium Improves Functional Recovery in a Rat Model of Spinal Cord Injury

    Directory of Open Access Journals (Sweden)

    Dasa Cizkova

    2018-03-01

    Full Text Available It was recently shown that the conditioned medium (CM of mesenchymal stem cells can enhance viability of neural and glial cell populations. In the present study, we have investigated a cell-free approach via CM from rat bone marrow stromal cells (MScCM applied intrathecally (IT for spinal cord injury (SCI recovery in adult rats. Functional in vitro test on dorsal root ganglion (DRG primary cultures confirmed biological properties of collected MScCM for production of neurosphere-like structures and axon outgrowth. Afterwards, rats underwent SCI and were treated with IT delivery of MScCM or vehicle at postsurgical Days 1, 5, 9, and 13, and left to survive 10 weeks. Rats that received MScCM showed significantly higher motor function recovery, increase in spared spinal cord tissue, enhanced GAP-43 expression and attenuated inflammation in comparison with vehicle-treated rats. Spared tissue around the lesion site was infiltrated with GAP-43-labeled axons at four weeks that gradually decreased at 10 weeks. Finally, a cytokine array performed on spinal cord extracts after MScCM treatment revealed decreased levels of IL-2, IL-6 and TNFα when compared to vehicle group. In conclusion, our results suggest that molecular cocktail found in MScCM is favorable for final neuroregeneration after SCI.

  17. Recovery of uranium from phosphoric acid medium by polymeric composite beads encapsulating organophosphorus extractants

    Energy Technology Data Exchange (ETDEWEB)

    Singh, D.K.; Yadav, K.K.; Varshney, L.; Singh, H. [Bhabha Atomic Research Centre, Mumbai 400 085 (India)

    2013-07-01

    The present study deals with the preparation and evaluation of the poly-ethersulfone (PES) based composite beads encapsulating synergistic mixture of D2EHPA and Cyanex 923 (at 4:1 mole ratio) for the separation of uranium from phosphoric acid medium. SEM was used for the characterization of the composite materials. Addition of 1% PVA (polyvinyl alcohol) improved the internal morphology and porosity of the beads. Additionally, microscopic examination of the composite bead confirmed central coconut type cavity surrounded by porous polymer layer of the beads through which exchange of metal ions take place. Effect of various experimental variables including aqueous acidity, metal ion concentration in aqueous feed, concentration of organic extractant inside the beads, extractant to polymer ratio, liquid to solid (L/S) ratio and temperature on the extraction of uranium was studied. Increase in acidity (1-6 M), L/S ratio (1- 10), metal ion concentration (0.2-3 g/L U{sub 3}O{sub 8}) and polymer to extractant ratio (1:4 -1:10) led to decrease in extraction of uranium. At 5.5 M (comparable to wet process phosphoric acid concentration) the extraction of uranium was about 85% at L/S ratio 5. Increase in extractant concentration inside the bead resulted in enhanced extraction of metal ion. Increase in temperature in the range of 30 to 50 Celsius degrees increased the extraction, whereas further increase to 70 C degrees led to the decrease in extraction of uranium. Amongst various reagents tested, stripping of uranium was quantitative by 12% Na{sub 2}CO{sub 3} solution. Polymeric beads were found to be stable and reusable up-to 10 cycles of extraction/stripping. (authors)

  18. NICHD Microscopy and Imaging Core (MIC)

    Data.gov (United States)

    Federal Laboratory Consortium — The NICHD Microscopy and Imaging Core (MIC) is designed as a multi-user research facility providing training and instrumentation for high resolution microscopy and...

  19. Development of biological coal gasification (MicGAS Process)

    Energy Technology Data Exchange (ETDEWEB)

    Walia, D.S.; Srivastava, K.C.

    1994-10-01

    The overall goal of the project is to develop an advanced, clean coal biogasification (MicGAS) Process. The objectives of the research during FY 1993--94 were to: (1) enhance kinetics of methane production (biogasification, biomethanation) from Texas lignite (TxL) by the Mic-1 consortium isolated and developed at ARCTECH, (2) increase coal solids loading, (3) optimize medium composition, and (4) reduce retention time. A closer analysis of the results described here indicate that biomethanation of TxL at >5% solids loading is feasible through appropriate development of nutrient medium and further adaptation of the microorganisms involved in this process. Further understanding of the inhibitory factors and some biochemical manipulations to overcome those inhibitions will hasten the process considerably. Results are discussed on the following: products of biomethanation and enhance of methane production including: bacterial adaptation; effect of nutrient amendment substitutes; effects of solids loading; effect of initial pH of the culture medium; effect of hydrogen donors and carbon balance.

  20. Importance of nutritional status in recovery from acute cholecystitis: benefit from enteral nutrition supplementation including medium chain triglycerides.

    Science.gov (United States)

    Nomura, Yukinobu; Inui, Kazuo; Yoshino, Junji; Wakabayashi, Takao; Okushima, Kazumu; Kobayashi, Takashi; Miyoshi, Hironao; Nakamura, Yuta

    2007-09-01

    This study was undertaken to clarify the importance of nutritional status in patients with acute cholecystitis, and also evaluate whether they benefited from enteral nutrition supplementation, including medium-chain triglycerides (MCT), during the convalescent stage. Patients with acute cholecystitis admitted to our hospital between April 1994 and March 2002 were classified into a poor nutrition group (n=40; total serum proteinnutrition group (n=71; >5.0 g/dl). Patients with poor nutrition were significantly more elderly than those with fair nutrition, and had significantly higher serum C-reactive protein (CRP) concentrations. The two groups did not differ significantly with respect to other laboratory data, gender distribution, or medical treatment. We supplemented ordinary meals with enteral nutrition including MCT in 16 patients during the convalescent stage (MCT group). We compared their length of hospital stay and days required to recovery to pre-admission functional status for activities of daily living (ADL) with the same intervals in 16 patients without supplementation (non-MCT group) selected to match for age, gender, and fair or poor nutritional status from among 111 patients. Hospitalizations were significantly longer in the poor nutrition group (43.0+/-2.2 days) than in the fair nutrition group (27.0+/-8.2 days). Significantly more days were required to recover ADL status in the poor nutrition group (12.0+/-7.2 days) than in the fair group (9.4+/-5.2 days). Hospitalizations were significantly shorter in the MCT group (20.1+/-15 days) than in the non-MCT group (35.4+/-12.8 days). Significantly fewer days were required to recover ADL status in the MCT group (10.9+/-7 days) than in the non-MCT group (13.1+/-6.8 days). Administration of enteral nutrition including MCT during convalescence from acute cholecystitis thus appears to promote functional recovery shorten hospital stay.

  1. mics para la Disfemia

    OpenAIRE

    Pomares Puig, María Pilar

    2015-01-01

    Desde la Facultad de Educación se vienen desarrollando diversas estrategias para fomentar el uso del cómic en distintos niveles escolares y profundizar en el conocimiento del mismo y ampliar la labor de divulgación que realiza la asociación de Unicómic http://unicomic.blogspot.com, centrándonos en los aspectos didácticos. La disfemia es un trastorno de la fluidez verbal y del ritmo del habla caracterizado por disfluencias consistentes en repeticiones y prolongaciones de sonidos y dificultad p...

  2. Determination Of Appropriate Antibiotic In Bacterial Meningitis Of Children Based On MIC

    Directory of Open Access Journals (Sweden)

    Noorbakhsh S

    2005-05-01

    sensitive to PNC;Chlora;Ceftria and vanco Resistant to all drugs and high MIC for cefotaxime;CIPRO>32mic/ml. E coli: Pseudomona Aerogenosa:: Ceftriaxon>256mic/ml/ /Genta>0.038mg/ml Imipenem>32mic/ml. Klebsiella; only Sensitive to Cipro Staph .Aureous:Sensitive to Clinda;Cipro;Chlora;Resistant toCeft;PNCand Cotri Conclusion: Most type of N.meningitidis;H.inf and S.pneumonia were sensitive to many drugs. Only minority of them were resistant to Ampicillin but sensitive to chloramphenicol and vice versa. limited number of pneumococcal resistance to penicillin is medium resistance( MIC:0.1-1 .we can treat this resistant type by increasing of penicillin dosage .The others were sensitive to all drugs. Therefore ampicillin and chloramphenicol are the drug of choice in empiric treatment of bacterial meningitis after neonatal period.

  3. Ranking alloys for susceptibility to MIC

    International Nuclear Information System (INIS)

    Scott, P.J.B.; Davies, M.; Goldie, J.

    1991-01-01

    This paper reports that laboratory experiments demonstrate that alloys containing 6 to 9% Mo are susceptible to microbiologically influenced corrosion attack. They also demonstrate that corrosion behavior in batch cultures do not correlate well with standard ferric chloride and pitting potential tests of the same alloys. In recent years, there has been an increasing awareness of the incidence of plant equipment failures caused by microbiologically influenced corrosion (MIC). This has led to the search for suitable testing techniques to look for MIC, which, in turn, has expanded the list of known susceptible alloys. Faced with field failures, the normal response has been to upgrade the alloy of construction. There is, for example, a common belief that the addition of more molybdenum to austenitic stainless steels conveys immunity (or at least increased resistance) to MIC. The basis for this is an extrapolation of localized corrosion data. The supposed correlation between molybdenum content and resistance to MIC has not yet been supported by a comprehensive testing program

  4. Spectrophotometric Determination of Microamounts of Uranium previous Extraction with TBP-MIC

    International Nuclear Information System (INIS)

    Vera Palomino, J.; Palomares Delgado, F.; Petrement, J.; Fernandez Cellini, R.

    1962-01-01

    Selective extraction of uranium in nitric acid medium with a mixture of Tbp-MIC (1:10) has been achieved. Aluminium nitrate was used as salting agent. Complexing agents were added in order to avoid extraction of impurities. Extraction conditions have been studied so that extraction is almost practically complete in a single run. (Author) 19 refs

  5. Generalidades de Queratitis Micótica

    Directory of Open Access Journals (Sweden)

    Manuel Fernando Buitrago Torrado

    2013-12-01

    Full Text Available La queratitis micótica es una importante causa de discapacidad visual en los países desarrollados. En los últimos años ha aumentado su incidencia en países de regiones tropicales, relacionado con el aumento de las conductas de riesgo como el uso indiscriminado de antifúngicos y corticoides oftálmicos en la práctica médica. La confirmación del diagnóstico es necesaria, no sólo en caso de queratitis micótica, sino también en otras enfermedades oculares infecciosas para así iniciar la terapia oportuna y exacta, y evitar el uso innecesario de antimicrobianos. El pronóstico visual de los pacientes dependerá del diagnóstico temprano y el tratamiento médico oportuno

  6. Optimization of culture medium for anaerobic production of rhamnolipid by recombinant Pseudomonas stutzeri Rhl for microbial enhanced oil recovery.

    Science.gov (United States)

    Zhao, F; Mandlaa, M; Hao, J; Liang, X; Shi, R; Han, S; Zhang, Y

    2014-08-01

    Response surface methodology was employed to enhance the anaerobic production of rhamnolipid by recombinant Pseudomonas stutzeri Rhl. Glycerol is a promising carbon source used to anaerobically produce rhamnolipid. In a Plackett-Burman design, glycerol, KH2 PO4 and yeast extract were significant factors. The proposed optimized medium contained the following: 46·55 g l(-1) glycerol; 3 g l(-1) NaNO3 ; 5·25 g l(-1) K2 HPO4 ·3H2 O; 5·71 g l(-1) KH2 PO4 ; 0·40 g l(-1) MgSO4 ·7H2 O; 0·13 g l(-1) CaCl2 ; 1·0 g l(-1) KCl; 1·0 g l(-1) NaCl; and 2·69 g l(-1) yeast extract. Using this optimized medium, we obtained an anaerobic yield of rhamnolipid of 3·12 ± 0·11 g l(-1) with a 0·85-fold increase. Core flooding test results also revealed that Ps. stutzeri Rhl grown in an optimized medium enhanced the oil recovery efficiency by 15·7%, which was 6·6% higher than in the initial medium. Results suggested that the optimized medium is a promising nutrient source that could effectively mobilize oil by enhancing the in situ production of rhamnolipid. The ex situ application of rhamnolipid for microbial enhanced oil recovery (MEOR) is costly and complex in terms of rhamnolipid production, purification and transportation. Compared with ex situ applications, the in situ production of rhamnolipid in anaerobic oil reservoir is more advantageous for MEOR. This study is the first to report the anaerobic production optimization of rhamnolipid. Results showed that the optimized medium enhanced not only the anaerobic production of rhamnolipid but also crude oil recovery. © 2014 The Society for Applied Microbiology.

  7. Recovery of perchloroethylene scrubbing medium generated in the refabrication of high-temperature gas-cooled reactor fuel

    Energy Technology Data Exchange (ETDEWEB)

    Judd, M.S.; Van Cleve, J.E. Jr.; Rainey, W.T. Jr.

    1976-11-01

    During the refabrication of high-temperature gas-cooled reactor (HTGR) fuel, perchloroethylene (C/sub 2/Cl/sub 4/) is used as the nonmoderating scrubbing medium to remove condensable hydrocarbons, carbon soot, and uranium-bearing particulates from the off-gas streams. The process by which the contaminated perchloroethylene is recycled is discussed.

  8. Recovery of perchloroethylene scrubbing medium generated in the refabrication of high-temperature gas-cooled reactor fuel

    International Nuclear Information System (INIS)

    Judd, M.S.; Van Cleve, J.E. Jr.; Rainey, W.T. Jr.

    1976-11-01

    During the refabrication of high-temperature gas-cooled reactor (HTGR) fuel, perchloroethylene (C 2 Cl 4 ) is used as the nonmoderating scrubbing medium to remove condensable hydrocarbons, carbon soot, and uranium-bearing particulates from the off-gas streams. The process by which the contaminated perchloroethylene is recycled is discussed

  9. Increased cefepime MIC for enterobacteriacae clinical isolates.

    Science.gov (United States)

    Najafi, Narges; Alikhani, Ahmad; Babamahmoudi, Farhang; Davoudi, Alireza; Ghasemiyan, Roya; Aliyan, Shahriar; Shoujaiifar, Arman

    2013-01-01

    Background : Cefepime was used as empirical treatment in ventilator-associated pneumonia (VAP) induced by gram-negative and gram-positive bacteria. This study aimed to determine the antimicrobial susceptibility pattern of cefepime against microorganism causing VAP in Mazandaran, North of Iran. This study was performed on VAP patients diagnosed with clinical pulmonary infection score (CPIS) scores in ICU of two hospitals. For each patient suspected of having VAP, quantitative culture of endotracheal aspiration (QEA) was performed and MIC was determined by micro dilution test. Data were collected and analyzed. Thirty- five cases of enterobacteriaceae were isolated orderly including E coli 13, P. aeruginosa 11, Enterobacter 7 and K. pneumonia 4 cases. All the isolated E. coli, Enterobacter and Klebsiella, 54.5% of P. aeruginosa isolated were fully resistant to cefepime. The results of this study show that cefepime is not a reasonable choice for empirical treatment of nosocomial pneumonia and VAP.

  10. Microbiologically Influenced Corrosion (MIC) in the Oil and Gas Industry

    DEFF Research Database (Denmark)

    Skovhus, Torben Lund; Eckert, Rickard

    2015-01-01

    Microbiologically influenced corrosion (MIC) is a serious corrosion threat that impacts the operating integrity and reliability of assets in the oil and gas, maritime, power generation, and other industries. Yet MIC is also commonly misunderstood, leading to ineffective mitigation programs, wasted...... and implement improved mitigation strategies and thereby reduce operating risk. Our experts provide guidance in applying the latest state-of-the-art molecular microbiological methods (MMM) and industry standards to properly diagnose MIC in operating assets and on failed components. With this understanding, MIC...... can be effectively addressed as part of the overall Corrosion Management System (CMS)....

  11. Evaluation of vancomycin MIC creep in Staphylococcus aureus.

    Science.gov (United States)

    Diaz, Raquel; Ramalheira, Elmano; Afreixo, Vera; Gago, Bruno

    2017-09-01

    Vancomycin is the primary treatment for methicillin-resistant Staphylococcus aureus (MRSA). However, an increasing proportion of MRSA isolates with high minimum inhibitory concentrations (MICs) within the susceptible range (vancomycin 'MIC creep') is being observed. The aim of this study was to assess the vancomycin MIC distribution for S. aureus isolates over a period of 4 years in Centro Hospitalar Baixo Vouga (Aveiro, Portugal) and to identify differences in vancomycin MIC determined by different susceptibility testing methods. For each S. aureus isolate, the vancomycin MIC was assayed by the VITEK ® 2 automated system and the broth microdilution testing method. The results showed significant differences in vancomycin MIC by different methods (P=0.021, sign test) and did not suggest the presence of vancomycin MIC creep during the study period. Vancomycin MIC creep is a regional problem, therefore it can only be assessed through the evaluation of local susceptibility profiles, and antibiogram based on real MIC assay should be an essential element in local MRSA infection clinical management. Copyright © 2017 International Society for Chemotherapy of Infection and Cancer. Published by Elsevier Ltd. All rights reserved.

  12. RECOVERY OF COPPER(II AND CHROMIUM(III FROM NITRATE MEDIUM WITH SALICYLIDENEANILINE DISSOLVED IN 1-OCTANOL

    Directory of Open Access Journals (Sweden)

    A. Guerdouh

    2016-05-01

    Full Text Available The solvent extraction of copper(II and chromium(III from nitrate medium with salicylideneaniline (HL is studied as a function of various parameters: pH, concentration of salicylideneaniline, contact time and the nature of anoin (nitrate and sulfate in aqueous phase. Chromium(III is not extracted by salicylideneaniline  diluted in 1-octanol. Copper(II is only extracted by salicylideneaniline and it was found that the highest extractability achieved to 95% at pH 4.9, The stoichiometry of the extracted species was determined by using the method of slope analysis. Elemental analysis, UV–vis and IR-spectra were used to confirm the structure. It is found that the copper (II is extracted as CuL2.2H2O Their equilibrium constant, distribution coefficient, percentage extraction (%E and free energy are also calculated.

  13. Beyond Bushfires: Community, Resilience and Recovery - a longitudinal mixed method study of the medium to long term impacts of bushfires on mental health and social connectedness.

    Science.gov (United States)

    Gibbs, Lisa; Waters, Elizabeth; Bryant, Richard A; Pattison, Philippa; Lusher, Dean; Harms, Louise; Richardson, John; MacDougall, Colin; Block, Karen; Snowdon, Elyse; Gallagher, Hugh Colin; Sinnott, Vikki; Ireton, Greg; Forbes, David

    2013-11-04

    Natural disasters represent an increasing threat both in terms of incidence and severity as a result of climate change. Although much is known about individual responses to disasters, much less is known about the social and contextual response and how this interacts with individual trajectories in terms of mental health, wellbeing and social connectedness. The 2009 bushfires in Victoria, Australia caused much loss of life, property destruction, and community disturbance. In order to progress future preparedness, response and recovery, it is crucial to measure and understand the impact of disasters at both individual and community levels. This study aims to profile the range of mental health, wellbeing and social impacts of the Victorian 2009 bushfires over time using multiple methodologies and involving multiple community partners. A diversity of communities including bushfire affected and unaffected will be involved in the study and will include current and former residents (at the time of the Feb 2009 fires). Participants will be surveyed in 2012, 2014 and, funding permitting, in 2016 to map the predictors and outcomes of mental health, wellbeing and social functioning. Ongoing community visits, as well as interviews and focus group discussions in 2013 and 2014, will provide both contextual information and evidence of changing individual and community experiences in the medium to long term post disaster. The study will include adults, adolescents and children over the age of 5. Conducting the study over five years and focussing on the role of social networks will provide new insights into the interplay between individual and community factors and their influence on recovery from natural disaster over time. The study findings will thereby expand understanding of long term disaster recovery needs for individuals and communities.

  14. Production of poly-3-(hydroxybutyrate-co-hydroxyvalerate) by Haloferax mediterranei using rice-based ethanol stillage with simultaneous recovery and re-use of medium salts.

    Science.gov (United States)

    Bhattacharyya, Anirban; Saha, Jayeeta; Haldar, Saubhik; Bhowmic, Asit; Mukhopadhyay, Ujjal Kumar; Mukherjee, Joydeep

    2014-03-01

    Haloferax mediterranei holds promise for competitive industrial-scale production of polyhydroxyalkanoate (PHA) because cheap carbon sources can be used thus lowering production costs. Although high salt concentration in production medium permits a non-sterile, low-cost process, salt disposal after process completion is a problem as current environmental standards do not allow total dissolved solids (TDS) above 2000 mg/l in discharge water. As the first objective of this work, the waste product of rice-based ethanol industry, stillage, was used for the production of PHA by H. mediterranei in shake flasks. Utilization of raw stillage led to 71 ± 2% (of dry cell weight) PHA accumulation and 16.42 ± 0.02 g/l PHA production. The product yield coefficient was 0.35 while 0.17 g/l h volumetric productivity was attained. Simultaneous reduction of BOD5 and COD values of stillage by 83% was accomplished. The PHA was isolated by osmotic lysis of cells, purification by sodium dodecyl sulfate and organic solvents. The biopolymer was identified as poly-3-(hydroxybutyrate-co-15.4 mol%-hydroxyvalerate) (PHBV). This first report on utilization of rice-based ethanol stillage for PHBV production by H. mediterranei is currently the most cost effective. As the second objective, directional properties of decanoic acid together with temperature dependence of water solubility in decanoic acid were applied for two-stage desalination of the spent stillage medium. We report for the first time, recovery and re-use of 96% of the medium salts for PHA production thus removing the major bottleneck in the potential application of H. mediterranei for industrial production of PHBV. Final discharge water had TDS content of 670 mg/l.

  15. EBP2R - an innovative enhanced biological nutrient recovery activated sludge system to produce growth medium for green microalgae cultivation.

    Science.gov (United States)

    Valverde-Pérez, Borja; Ramin, Elham; Smets, Barth F; Plósz, Benedek Gy

    2015-01-01

    Current research considers wastewater as a source of energy, nutrients and water and not just a source of pollution. So far, mainly energy intensive physical and chemical unit processes have been developed to recover some of these resources, and less energy and resource demanding alternatives are needed. Here, we present a modified enhanced biological phosphorus removal and recovery system (referred to as EBP2R) that can produce optimal culture media for downstream micro-algal growth in terms of N and P content. Phosphorus is recovered as a P-stream by diversion of some of the effluent from the upstream anaerobic reactor. By operating the process at comparably low solids retention times (SRT), the nitrogen content of wastewater is retained as free and saline ammonia, the preferred form of nitrogen for most micro-algae. Scenario simulations were carried out to assess the capacity of the EBP2R system to produce nutrient rich organic-carbon depleted algal cultivation media of target composition. Via SRT control, the quality of the constructed cultivation media can be optimized to support a wide range of green micro-algal growth requirements. Up to 75% of the influent phosphorus can be recovered, by diverting 30% of the influent flow as a P-stream at an SRT of 5 days. Through global sensitivity analysis we find that the effluent N-to-P ratio and the P recovered are mainly dependent on the influent quality rather than on biokinetics or stoichiometry. Further research is needed to demonstrate that the system performance predicted through the model-based design can be achieved in reality. Copyright © 2014 Elsevier Ltd. All rights reserved.

  16. Engine Load Effects on the Energy and Exergy Performance of a Medium Cycle/Organic Rankine Cycle for Exhaust Waste Heat Recovery

    Directory of Open Access Journals (Sweden)

    Peng Liu

    2018-02-01

    Full Text Available The Organic Rankine Cycle (ORC has been proved a promising technique to exploit waste heat from Internal Combustion Engines (ICEs. Waste heat recovery systems have usually been designed based on engine rated working conditions, while engines often operate under part load conditions. Hence, it is quite important to analyze the off-design performance of ORC systems under different engine loads. This paper presents an off-design Medium Cycle/Organic Rankine Cycle (MC/ORC system model by interconnecting the component models, which allows the prediction of system off-design behavior. The sliding pressure control method is applied to balance the variation of system parameters and evaporating pressure is chosen as the operational variable. The effect of operational variable and engine load on system performance is analyzed from the aspects of energy and exergy. The results show that with the drop of engine load, the MC/ORC system can always effectively recover waste heat, whereas the maximum net power output, thermal efficiency and exergy efficiency decrease linearly. Considering the contributions of components to total exergy destruction, the proportions of the gas-oil exchanger and turbine increase, while the proportions of the evaporator and condenser decrease with the drop of engine load.

  17. MIC in long oil pipelines: diagnosis, treatment and monitoring

    Energy Technology Data Exchange (ETDEWEB)

    Jenneman, Gary; Harris, Jennifer; Webb, Robert [ConocoPhillips (Canada)

    2011-07-01

    The paper presents the diagnosis, treatment and monitoring of microbial influenced corrosion (MIC) in long oil pipelines. The presence of inorganic solids, bacteria, gases and organic acids in produced water in the oil pipelines causes MIC, which is hard to detect or test and it does not produce any unique type of corrosion. Chemical analysis of water from pig runs is presented in a tabular form and a graphical analysis of pig sludge solids is shown. From the biometabolite analysis, 23 putative hydrocarbon biometabolites were identified and biometabolites for the anaerobic biodegradation of aromatic HC were also detected. Operational considerations include the history of MIC in upstream pipelines, water slugging, and presence of suspended solids, among others. From microbiological, chemical, metallurgical and operational evidence it was suggested that MIC is a likely mechanism. The mitigation program is described and suggestions for successful mitigation measures include removal of oxygen sources, scale inhibitor injection, and increasing CO2 inhibitor concentration.

  18. Effect of medium composition on static and cidal activity of amphotericin B, itraconazole, voriconazole, posaconazole and terbinafine against Aspergillus fumigatus: a multicenter study.

    NARCIS (Netherlands)

    Tortorano, A.M.; Danaoui, E.; Meletiadis, J.; Mallie, M.; Viviani, M.A.; Piens, M.A.; Rigoni, A.L.; Bastide, J.M.; Grillot, R.

    2002-01-01

    The effect of the medium composition on the fungistatic (MIC) and fungicidal (MLC) activity of amphotericin B, itraconazole, voriconazole, posaconazole and terbinafine against four Aspergillus fumigatus strains has been investigated by four European laboratories. MICs were determined by broth

  19. El cómic español desde 1995

    Directory of Open Access Journals (Sweden)

    Díaz de Guereñu, Juan Manuel

    2011-09-01

    Full Text Available In the last fifteen years comic has changed dramatically in Spain. The small size of the comics industry in the Spanish market doesn’t allow comic creators to turn his job into a profession, but the medium has attained prestige, critical attention on the cultural spaces and a place in the bookstores. Those changes are the consequence of some significant facts of the period: after the extinction of former comic magazines, comic books substituted them as the first format for comics edition, and a number of critical fanzines and self-edited fanzines and magazines were published by the authors themselves. Newborn and independent smallpress, more focused on the aesthetic values than on the economic profits of comics edition, have defined the new author comic, often printed in the format of books and associated to the “graphic novel” label.

    En los últimos quince años, el cómic ha cambiado mucho en España. Aunque el escaso peso de la industria del cómic no permite a los autores vivir como profesionales, el medio ha ganado prestigio, atención crítica en las páginas culturales y un lugar en las librerías. Dichos cambios son consecuencia de algunos hechos significativos del periodo: tras la desaparición de las revistas, las sustituyeron cuadernillos o comic-books como soporte fundamental del cómic, y proliferaron revistas críticas de aficionados y fanzines o revistas autoeditadas por los autores. Nuevas editoriales, pequeñas e independientes, más atentas a los valores estéticos que a los comerciales, han definido el nuevo cómic de autor, a menudo identificado con el formato libro y la etiqueta “novela gráfica”.

  20. Operational measures for the mitigation of MIC [microbiologically influenced corrosion

    International Nuclear Information System (INIS)

    Johnson, C.J.

    1989-01-01

    Although entitled Operational Measure, this section of the workshop encompasses aspects of mitigating MIC by controlling the hydraulic characteristics of a system. In order for operational considerations outside of the chemical treatment program to be effective, the system must be designed, constructed or modified, and maintained with MIC in mind. Since other papers in these proceedings discuss in detail the proper selection of materials, chemical treatments and detection of monitoring techniques, this paper is limited to quidelines for mitigating MIC and its effects by the mechanical design, maintenance and operation of the system. The key concept behind this philosophy is the synergistic relationships among microbes and among microbes and larger biofouling organisms. If the slime formers or other marine organisms can be prevented from attaching to the components, conducive environments for attack by other species is avoided

  1. Wild-type MIC distributions for aminoglycoside and cyclic polypeptide antibiotics used for treatment of Mycobacterium tuberculosis infections.

    Science.gov (United States)

    Juréen, P; Angeby, K; Sturegård, E; Chryssanthou, E; Giske, C G; Werngren, J; Nordvall, M; Johansson, A; Kahlmeter, G; Hoffner, S; Schön, T

    2010-05-01

    The aminoglycosides and cyclic polypeptides are essential drugs in the treatment of multidrug-resistant tuberculosis, underscoring the need for accurate and reproducible drug susceptibility testing (DST). The epidemiological cutoff value (ECOFF) separating wild-type susceptible strains from non-wild-type strains is an important but rarely used tool for indicating susceptibility breakpoints against Mycobacterium tuberculosis. In this study, we established wild-type MIC distributions on Middlebrook 7H10 medium for amikacin, kanamycin, streptomycin, capreomycin, and viomycin using 90 consecutive clinical isolates and 21 resistant strains. Overall, the MIC variation between and within runs did not exceed +/-1 MIC dilution step, and validation of MIC values in Bactec 960 MGIT demonstrated good agreement. Tentative ECOFFs defining the wild type were established for all investigated drugs, including amikacin and viomycin, which currently lack susceptibility breakpoints for 7H10. Five out of seven amikacin- and kanamycin-resistant isolates were classified as susceptible to capreomycin according to the current critical concentration (10 mg/liter) but were non-wild type according to the ECOFF (4 mg/liter), suggesting that the critical concentration may be too high. All amikacin- and kanamycin-resistant isolates were clearly below the ECOFF for viomycin, and two of them were below the ECOFF for streptomycin, indicating that these two drugs may be considered for treatment of amikacin-resistant strains. Pharmacodynamic indices (peak serum concentration [Cmax]/MIC) were more favorable for amikacin and viomycin compared to kanamycin and capreomycin. In conclusion, our data emphasize the importance of establishing wild-type MIC distributions for improving the quality of drug susceptibility testing against Mycobacterium tuberculosis.

  2. Wild-Type MIC Distributions for Aminoglycoside and Cyclic Polypeptide Antibiotics Used for Treatment of Mycobacterium tuberculosis Infections▿

    Science.gov (United States)

    Juréen, P.; Ängeby, K.; Sturegård, E.; Chryssanthou, E.; Giske, C. G.; Werngren, J.; Nordvall, M.; Johansson, A.; Kahlmeter, G.; Hoffner, S.; Schön, T.

    2010-01-01

    The aminoglycosides and cyclic polypeptides are essential drugs in the treatment of multidrug-resistant tuberculosis, underscoring the need for accurate and reproducible drug susceptibility testing (DST). The epidemiological cutoff value (ECOFF) separating wild-type susceptible strains from non-wild-type strains is an important but rarely used tool for indicating susceptibility breakpoints against Mycobacterium tuberculosis. In this study, we established wild-type MIC distributions on Middlebrook 7H10 medium for amikacin, kanamycin, streptomycin, capreomycin, and viomycin using 90 consecutive clinical isolates and 21 resistant strains. Overall, the MIC variation between and within runs did not exceed ±1 MIC dilution step, and validation of MIC values in Bactec 960 MGIT demonstrated good agreement. Tentative ECOFFs defining the wild type were established for all investigated drugs, including amikacin and viomycin, which currently lack susceptibility breakpoints for 7H10. Five out of seven amikacin- and kanamycin-resistant isolates were classified as susceptible to capreomycin according to the current critical concentration (10 mg/liter) but were non-wild type according to the ECOFF (4 mg/liter), suggesting that the critical concentration may be too high. All amikacin- and kanamycin-resistant isolates were clearly below the ECOFF for viomycin, and two of them were below the ECOFF for streptomycin, indicating that these two drugs may be considered for treatment of amikacin-resistant strains. Pharmacodynamic indices (peak serum concentration [Cmax]/MIC) were more favorable for amikacin and viomycin compared to kanamycin and capreomycin. In conclusion, our data emphasize the importance of establishing wild-type MIC distributions for improving the quality of drug susceptibility testing against Mycobacterium tuberculosis. PMID:20237102

  3. Predominant MIC Mechanisms in the Oil and Gas Industry

    Science.gov (United States)

    literature, terms such as microbial corrosion, biocorrosion, microbially influenced/induced corrosion, and biodegradation are often applied. All descriptions...express that microorganisms (bacteria, archaea, and fungi) influence the corrosion process of a given material. In this chapter, an overview of the common MIC mechanisms encountered in the oil and gas industry is presented.

  4. Gene-specific cell labeling using MiMIC transposons.

    Science.gov (United States)

    Gnerer, Joshua P; Venken, Koen J T; Dierick, Herman A

    2015-04-30

    Binary expression systems such as GAL4/UAS, LexA/LexAop and QF/QUAS have greatly enhanced the power of Drosophila as a model organism by allowing spatio-temporal manipulation of gene function as well as cell and neural circuit function. Tissue-specific expression of these heterologous transcription factors relies on random transposon integration near enhancers or promoters that drive the binary transcription factor embedded in the transposon. Alternatively, gene-specific promoter elements are directly fused to the binary factor within the transposon followed by random or site-specific integration. However, such insertions do not consistently recapitulate endogenous expression. We used Minos-Mediated Integration Cassette (MiMIC) transposons to convert host loci into reliable gene-specific binary effectors. MiMIC transposons allow recombinase-mediated cassette exchange to modify the transposon content. We developed novel exchange cassettes to convert coding intronic MiMIC insertions into gene-specific binary factor protein-traps. In addition, we expanded the set of binary factor exchange cassettes available for non-coding intronic MiMIC insertions. We show that binary factor conversions of different insertions in the same locus have indistinguishable expression patterns, suggesting that they reliably reflect endogenous gene expression. We show the efficacy and broad applicability of these new tools by dissecting the cellular expression patterns of the Drosophila serotonin receptor gene family. © The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research.

  5. Spectrophotometric Determination of Microamounts of Uranium previous Extraction with TBP-MIC; Determinacion Espectrofotometrica de Microcantidades de Uranio previa extraccin con Metilisobutilcetona-Fosfato de Tributilo

    Energy Technology Data Exchange (ETDEWEB)

    Vera Palomino, J; Palomares Delgado, F; Petrement, J; Fernandez Cellini, R

    1962-07-01

    Selective extraction of uranium in nitric acid medium with a mixture of Tbp-MIC (1:10) has been achieved. Aluminium nitrate was used as salting agent. Complexing agents were added in order to avoid extraction of impurities. Extraction conditions have been studied so that extraction is almost practically complete in a single run. (Author) 19 refs.

  6. Wild-type MIC distributions of four fluoroquinolones active against Mycobacterium tuberculosis in relation to current critical concentrations and available pharmacokinetic and pharmacodynamic data.

    Science.gov (United States)

    Angeby, K A; Jureen, P; Giske, C G; Chryssanthou, E; Sturegård, E; Nordvall, M; Johansson, A G; Werngren, J; Kahlmeter, G; Hoffner, S E; Schön, T

    2010-05-01

    To describe wild-type distributions of the MIC of fluoroquinolones for Mycobacterium tuberculosis in relation to current critical concentrations used for drug susceptibility testing and pharmacokinetic/pharmacodynamic (PK/PD) data. A 96-stick replicator on Middlebrook 7H10 medium was used to define the MICs of ciprofloxacin, ofloxacin, moxifloxacin and levofloxacin for 90 consecutive clinical strains and 24 drug-resistant strains. The MICs were compared with routine BACTEC 460 susceptibility results and with MIC determinations in the BACTEC MGIT 960 system in a subset of strains using ofloxacin as a class representative. PK/PD data for each drug were reviewed in relation to the wild-type MIC distribution. The wild-type MICs of ciprofloxacin, ofloxacin, moxifloxacin and levofloxacin were distributed from 0.125 to 1, 0.25 to 1, 0.032 to 0.5 and 0.125 to 0.5 mg/L, respectively. The MIC data correlated well with the BACTEC 960 MGIT and BACTEC 460 results. PD indices were the most favourable for levofloxacin, followed by moxifloxacin, ofloxacin and ciprofloxacin. We propose S (susceptible) MIC data could shift the ECOFFs for ofloxacin and levofloxacin one dilution upwards. The proposed ECOFFs may be more appropriate if used as clinical breakpoints on Middlebrook 7H10 agar than the current critical concentrations of S

  7. CoMIC, the hidden dynamics of mitochondrial inner compartments.

    Science.gov (United States)

    Cho, Bongki; Sun, Woong

    2017-12-01

    Mitochondria have evolutionarily, functionally and structurally distinct outer- (OMM) and inner-membranes (IMM). Thus, mitochondrial morphology is controlled by independent but coordinated activity of fission and fusion of the OMM and IMM. Constriction and division of the OMM are mediated by endocytosis-like machineries, which include dynamin-related protein 1 with additional cytosolic vesicle scissoring machineries such as actin filament and Dynamin 2. However, structural alteration of the IMM during mitochondrial division has been poorly understood. Recently, we found that the IMM and the inner compartments undergo transient and reversible constriction prior to the OMM division, which we termed CoMIC, Constriction of Mitochondrial Inner Compartment. In this short review, we further discuss the evolutionary perspective and the regulatory mechanism of CoMIC during mitochondrial division. [BMB Reports 2017; 50(12): 597-598].

  8. Threshold SRB populations for MIC of stainless alloys

    International Nuclear Information System (INIS)

    Angell, P.; Urbanic, K.; Gendron, T.S.

    1997-12-01

    The three CANDU reactor sites on the Great Lakes exhibit differences in susceptibility to microbially influenced corrosion (MIC) of heat exchanger tubes, despite similar colonization of sulfate-reducing bacteria (SRB). Therefore, it was suspected that bacterial activity, rather than numbers, is responsible for pit initiation. Accelerated corrosion tests are being used to examine the relationship between SRB colonization and pitting activity on stainless alloy heat exchanger tubes. Experimental conditions model those of the natural systems. At present, there appears to be little correlation between bacterial numbers and pit initiation. However, there does appear to be a correlation between bacterial activity (causing a decrease in corrosion potential, as a function of sulfide production), and pit initiation. Data are being collected to develop a model to predict MIC for the CHECWORKS service water module. (author)

  9. Test methods for microbiologically influenced corrosion (MIC) in marine environments

    International Nuclear Information System (INIS)

    Little, B.; Wagner, P.; Mansfeld, F.

    1992-01-01

    Electrochemical techniques such as measurements of corrosion and redox potentials, polarization curves, polarization resistance, electrochemical impedance and electrochemical noise have been used to evaluate the impact of marine microorganisms on corrosion processes. Surface analytical techniques including microbiological culturing, scanning electron microscopy, microprobes and microelectrodes have been used to characterize metal surfaces after exposure to marine waters. A combination of electrochemical, surface analytical and microbiological techniques is the most promising approach for determining mechanisms of MIC

  10. Application of mineral insulated cable (MIC) in Tokamak fusion reactor

    International Nuclear Information System (INIS)

    Luo Tianyong; Jiang Jiaming; Cen Yishun

    2014-01-01

    To avoid the instability of plasma and achieve some experimental tasks in Tokamak fusion reactor, many in-vessel coils are designed such as the coils to mitigate the effect of Edge Localized Modes (ELMs coils) and the coils to provide vertical stabilization (VS coils). The in-vessel location presents special challenges in terms of nuclear radiation and temperature, and requires the use of mineral-insulated conductors. The in-vessel coils in ITER are designed to be Mineral-insulated Cable (MIC) with three-layer structures. The inner is hollow-core tube made by OFHC or CuCrZr, the middle is the insulation layer made by Mgo and the outer is the jacket by SS316L or Inconel 718. To control the effect of Edge Localized Modes and vertical instability of plasma, the MIC in-vessel coils shall be used in HL-2M. More details about the application of MIC in Tokamak fusion reactor will be shown in this report. (authors)

  11. Recovery of insulin sensitivity and optimal body composition after rapid weight loss in obese dogs fed a high-protein medium-carbohydrate diet.

    Science.gov (United States)

    André, A; Leriche, I; Chaix, G; Thorin, C; Burger, M; Nguyen, P

    2017-06-01

    This study investigated the effects of an experimental high-protein medium-carbohydrate diet (protein level, 46% metabolizable energy, ME). First, postprandial plasma glucose and insulin kinetics were determined in steady-state overweight/obese Beagle dogs (28%-41% excess body weight) for an experimental high-protein medium-carbohydrate diet (protein level, 46% ME) and a commercial high-carbohydrate medium-protein diet (protein level, 24%ME) in obese dogs. Secondly, all the dogs were included in a weight loss programme. They were fed the high-protein medium-carbohydrate diet, and the energy allocation was gradually reduced until they reached their optimal body weight. Insulin sensitivity and body composition were evaluated before and after weight loss using a euglycaemic-hyperinsulinaemic clamp and the deuterium oxide dilution technique respectively. For statistical analysis, linear mixed effect models were used with a significance level of 5%. Postprandial plasma glucose and insulin concentrations were substantially lower with the high-protein medium-carbohydrate diet than the high-carbohydrate medium-protein diet. These differences can be explained mainly by the difference in carbohydrate content between the two diets. Energy restriction (35% lower energy intake than in the obese state) resulted in a 2.23 ± 0.05% loss in body weight/week, and the dogs reached their optimal body weight in 12-16 weeks. Weight loss was associated with a significant increase in insulin sensitivity. The high-protein medium-carbohydrate diet allowed fat-free mass preservation despite a relatively high rate of weekly weight loss. The increase in insulin sensitivity indicated improved control of carbohydrate metabolism, possible due to weight loss and to the nature of the diet. Thus, a high-protein medium-carbohydrate diet is a good nutritional solution for managing the weight of overweight dogs. This diet may improve glycaemic control, which could be beneficial for preventing or

  12. Peran Public Speaking dalam Kegiatan Open Mic (Studi tentang Peran Public Speaking terhadap Kemampuan Comic dalam Kegiatan Open Mic Komunitas Stand Up Indo Kota Medan)

    OpenAIRE

    Rovis, Disa Yumna

    2016-01-01

    This study, entitled "The Role of Public Speaking on Open Mic Activity". The aim of the research is knowing the public speaking proses and the use of public speaking on the ability of comic on open mic activity. Public speaking theory is used for this research. Descriptive qualitative method is used in this research by nonparticipant observation tecnique through interviewing the comic. Based on this research, open mic activity uses the specific elements of public speaking. They are, the speak...

  13. Mastite micótica em ruminantes causada por leveduras

    OpenAIRE

    Spanamberg,Andréia; Sanches,Edna Maria Cavallini; Santurio,Janio Morais; Ferreiro,Laerte

    2009-01-01

    A ocorrência de casos esporádicos de mastite causados por microrganismos de origem ambiental pode ser considerada como emergente e as leveduras, os fungos leveduriformes e os filamentosos são alguns dos principais agentes envolvidos. Em relação à mastite micótica, as leveduras são freqüentemente causas de infecções da glândula mamária em animais produtores de leite. A maior parte dos casos ocorre sob a forma de surtos localizados e/ou após tratamento com antimicrobianos. Os principais gêneros...

  14. El vocabulario de las armas en micénico

    Directory of Open Access Journals (Sweden)

    Bernabé, Alberto

    2007-12-01

    Full Text Available Systematic analysis of rise, structure, and development of the words referred to weapons in Mycenaean tablets and in first Millennium Greek. The results of application of linguistic or philological methods can so be collated with ones achieved by archaeologists.

    Estudio sistemático de la creación, estructura y desarrollo del vocabulario referido a las armas en las tablillas micénicas y en el griego posterior. Los resultados obtenidos por métodos lingüísticos o filológicos pueden así ser cotejados con los logrados por la arqueología.

  15. Comparison and Recovery of Escherichia coli and Thermotolerant Coliforms in Water with a Chromogenic Medium Incubated at 41 and 44.5°C

    Science.gov (United States)

    Alonso, Jose L.; Soriano, Adela; Carbajo, Oscar; Amoros, Inmaculada; Garelick, Hemda

    1999-01-01

    This study compared the performance of a commercial chromogenic medium, CHROMagarECC (CECC), and CECC supplemented with sodium pyruvate (CECCP) with the membrane filtration lauryl sulfate-based medium (mLSA) for enumeration of Escherichia coli and non-E. coli thermotolerant coliforms (KEC). To establish that we could recover the maximum KEC and E. coli population, we compared two incubation temperature regimens, 41 and 44.5°C. Statistical analysis by the Fisher test of data did not demonstrate any statistically significant differences (P = 0.05) in the enumeration of E. coli for the different media (CECC and CECCP) and incubation temperatures. Variance analysis of data performed on KEC counts showed significant differences (P = 0.01) between KEC counts at 41 and 44.5°C on both CECC and CECCP. Analysis of variance demonstrated statistically significant differences (P = 0.05) in the enumeration of total thermotolerant coliforms (TTCs) on CECC and CECCP compared with mLSA. Target colonies were confirmed to be E. coli at a rate of 91.5% and KEC of likely fecal origin at a rate of 77.4% when using CECCP incubated at 41°C. The results of this study showed that CECCP agar incubated at 41°C is efficient for the simultaneous enumeration of E. coli and KEC from river and marine waters. PMID:10427079

  16. Recovery of Cd(II), Co(II) and Ni(II) from Chloride Medium by Solvent Extraction Using CYANEX 923 and CYANEX 272 I

    International Nuclear Information System (INIS)

    Ahmed, M.; El Dessouky, S.I.; El-Nadi, Y.A.; Daoud, J.A.; Saad, E.A.

    2008-01-01

    The paper aims to study the extraction and separation of Cd(II), Co(II) and Ni(II) from their mixtures in hydrochloric acid medium with CYANEX 923 in kerosene. Preliminary investigations showed that only Cd(II) is extracted with CYANEX 923 while Co(II) and Ni(II) are not extracted. Different parameters affecting the extraction of Cd(II) with CYANEX 923 such as hydrochloric acid, hydrogen ion, extractant and metal concentrations, temperature investigations were also investigated. The stoichiometry of the extracted metal species investigated was found to be HCdCl 3 . 2 CYANEX 923. The stripping of the extracted Cd(II) species is obtained with 0.1 M HCl solution. Co(II) was found to be extracted with CYANEX 272 at ph 5.8 leaving Ni(II) in the solution. A developed process for the sequential of Cd(II), Co(II) and Ni(II) from their mixture in hydrochloric acid medium is proposed

  17. Effect of culture medium on polymer production and temperature on recovery of polymer produced from newly identified Rhyzopus oryzae ST29

    Directory of Open Access Journals (Sweden)

    Tipparat Hongpattarakere

    2008-04-01

    Full Text Available Thermotolerant fungal isolate ST29 was identified by observing on cell morphology and molecular technique based on internal transcribed spacer (ITS gene to be Rhizopus oryzae. Among four culture media tested, the strain exhibited the highest growth in yeast malt extract (YM medium (4.87 g/l, followed by Sabouraud dextrose broth (SDB (4.25 g/l, potato dextrose broth (PDB (4.10 g/l and palm oil mill effluent (POME (3.29 g/l, respectively, after 4 days cultivation at 45oC. However, the strain was found to produce polymer only in POME medium at 45oC, but not in the three synthetic media tested. Effect of temperature on separation of the biopolymer produced by this fungal strain was studied by incubating the culture broth in water bath with temperatures in the range of room temperature to 70oC. The biopolymer was recovered by filtration, centrifugation, and precipitation by adding 4 volumes of 95% ethanol, then freeze-drying. These temperatures therefore had no influence on the biopolymer yields (5.58-5.78 g/l or on biomass yields (2.90-3.29 g/l.

  18. An accelerated electrochemical MIC test for stainless alloys

    International Nuclear Information System (INIS)

    Gendron, T.S.; Cleland, R.D.

    1994-01-01

    Previous work in our laboratory and elsewhere has suggested that MIC of stainless steels and nickel-base alloys occurs in locally anaerobic regions that support the growth of sulfate reducing bacteria (SRB). The cathodic reaction is provided by oxygen reduction at remote sites. Such a coupling between anode and cathode is difficult to reproduce in the laboratory, but can be simulated indirectly using a double electrochemical cell, as in previous work. A more realistic simulation using a single aerated electrochemical cell has now been developed, in which a second organism (P. aeruginosa) is used to provide an anoxic habitat for SRB growth and possibly a source of organic carbon, within a layer of silt. A bare alloy electrode is used as the oxygen cathode. Tests of this kind using rigorous microbiological procedures have generated pitting corrosion of several alloys in low chloride media simulating freshwater heat exchanger conditions. Similar test procedures are applicable to other environments of interest to this symposium

  19. Vancomycin AUC/MIC ratio and 30-day mortality in patients with Staphylococcus aureus bacteremia.

    Science.gov (United States)

    Holmes, Natasha E; Turnidge, John D; Munckhof, Wendy J; Robinson, J Owen; Korman, Tony M; O'Sullivan, Matthew V N; Anderson, Tara L; Roberts, Sally A; Warren, Sanchia J C; Gao, Wei; Howden, Benjamin P; Johnson, Paul D R

    2013-04-01

    A ratio of the vancomycin area under the concentration-time curve to the MIC (AUC/MIC) of ≥ 400 has been associated with clinical success when treating Staphylococcus aureus pneumonia, and this target was recommended by recently published vancomycin therapeutic monitoring consensus guidelines for treating all serious S. aureus infections. Here, vancomycin serum trough levels and vancomycin AUC/MIC were evaluated in a "real-world" context by following a cohort of 182 patients with S. aureus bacteremia (SAB) and analyzing these parameters within the critical first 96 h of vancomycin therapy. The median vancomycin trough level at this time point was 19.5 mg/liter. There was a significant difference in vancomycin AUC/MIC when using broth microdilution (BMD) compared with Etest MIC (medians of 436.1 and 271.5, respectively; P AUC/MIC of ≥ 400 using BMD was not associated with lower 30-day all-cause or attributable mortality from SAB (P = 0.132 and P = 0.273, respectively). However, an alternative vancomycin AUC/MIC of >373, derived using classification and regression tree analysis, was associated with reduced mortality (P = 0.043) and remained significant in a multivariable model. This study demonstrated that we obtained vancomycin trough levels in the target therapeutic range early during the course of therapy and that obtaining a higher vancomycin AUC/MIC (in this case, >373) within 96 h was associated with reduced mortality. The MIC test method has a significant impact on vancomycin AUC/MIC estimation. Clinicians should be aware that the current target AUC/MIC of ≥ 400 was derived using the reference BMD method, so adjustments to this target need to be made when calculating AUC/MIC ratio using other MIC testing methods.

  20. Microbial induced corrosion (MIC) on DHP copper by Desulfovibrio desulfuricans and Bacillus megaterium strains in media simulating heater waters

    International Nuclear Information System (INIS)

    Zumelzu, E.; Cabezas, C.; Schoebitz, R.; Ugarte, R.; Rodriguez, E.D.; Rios, J.

    2003-01-01

    The complexity and diversity of microbial populations in water heating systems of steam generators make it necessary to study the magnitude of the metabolic activity of bacteria and biofilm development that may lead to degradation of metal components through microbial induced corrosion (MIC). Electrolytes simulating the conditions found in heater water networks were used to induce biofilm formation on DHP copper coupons by Desulfovibrio desulfuricans DSMZ and Bacillus megaterium C10, a commercial strain and an isolate from these waters, respectively. In order to enhance their action, industrial waters enriched with the minimum nutrient content such as sodium lactate and sodium sulphite for the DSMZ strain and glucose, proteose peptone and starch for the C10 strain were employed. Biofilm formation was studied under controlled temperature, time, shaking, pH and concentrations of the media used in this study. Then, the samples were electrochemically tested in an artificial solution of sea water as control medium, based on the hypothesis that the action of an aggressive biofilm/electrolyte medium generates damaged and non-damaged areas on the metal surface, and assuming that the sea water trial can detect the latter. Hence, a higher anodic current was associated with a lower degradation of the metal surface by the action of one of the media under study. All these trials were performed along with bacterial count, scanning electron microscopy (SEM) and atomic absorption spectroscopy (AAS). Furthermore, it was possible to identify under which conditions MIC on DHP copper occurred and complex mechanisms from retention of cations to diffusion processes at the biofilm/tested media interface level were proposed. Surface corrosion by MIC took place on DHP copper; therefore, greater control on the treatment of industrial waters is highly desirable. (author)

  1. A comparison of the medium-term impact and recovery of the Pakistan floods and the Haiti earthquake: objective and subjective measures.

    Science.gov (United States)

    Weiss, William M; Kirsch, Thomas D; Doocy, Shannon; Perrin, Paul

    2014-06-01

    The 2010 Haiti earthquake and Pakistan floods were similar in their massive human impact. Although the specific events were very different, the humanitarian response to disasters is supposed to achieve the same ends. This paper contrasts the disaster effects and aims to contrast the medium-term response. In January 2011, similarly structured population-based surveys were carried out in the most affected areas using stratified cluster designs (80×20 in Pakistan and 60×20 in Haiti) with probability proportional to size sampling. Displacement persisted in Haiti and Pakistan at 53% and 39% of households, respectively. In Pakistan, 95% of households reported damage to their homes and loss of income or livelihoods, and in Haiti, the rates were 93% and 85%, respectively. Frequency of displacement, and income or livelihood loss, were significantly higher in Pakistan, whereas disaster-related deaths or injuries were significantly more prevalent in Haiti. Given the rise in disaster frequency and costs, and the volatility of humanitarian funding streams as a result of the recent global financial crisis, it is increasingly important to measure the impact of humanitarian response against the goal of a return to normalcy.

  2. Comparative antianaerobic activities of doripenem determined by MIC and time-kill analysis.

    Science.gov (United States)

    Credito, Kim L; Ednie, Lois M; Appelbaum, Peter C

    2008-01-01

    Against 447 anaerobe strains, the investigational carbapenem doripenem had an MIC 50 of 0.125 microg/ml and an MIC 90 of 1 microg/ml. Results were similar to those for imipenem, meropenem, and ertapenem. Time-kill studies showed that doripenem had very good bactericidal activity compared to other carbapenems, with 99.9% killing of 11 strains at 2x MIC after 48 h.

  3. Comparative Antianaerobic Activities of Doripenem Determined by MIC and Time-Kill Analysis▿

    Science.gov (United States)

    Credito, Kim L.; Ednie, Lois M.; Appelbaum, Peter C.

    2008-01-01

    Against 447 anaerobe strains, the investigational carbapenem doripenem had an MIC50 of 0.125 μg/ml and an MIC90 of 1 μg/ml. Results were similar to those for imipenem, meropenem, and ertapenem. Time-kill studies showed that doripenem had very good bactericidal activity compared to other carbapenems, with 99.9% killing of 11 strains at 2× MIC after 48 h. PMID:17938185

  4. Comparison of Neisseria gonorrhoeae MICs Obtained by Etest and Agar Dilution for Ceftriaxone, Cefpodoxime, Cefixime and Azithromycin.

    Science.gov (United States)

    Gose, Severin; Kong, Carol J; Lee, Yer; Samuel, Michael C; Bauer, Heidi M; Dixon, Paula; Soge, Olusegun O; Lei, John; Pandori, Mark

    2013-10-24

    We evaluated Neisseria gonorrhoeae Etest minimum inhibitory concentrations (MICs) relative to agar dilution MICs for 664 urethral isolates for ceftriaxone (CRO) and azithromycin (AZM), 351 isolates for cefpodoxime (CPD) and 315 isolates for cefixime (CFM). Etest accurately determined CPD, CFM and AZM MICs, but resulted in higher CRO MICs. © 2013. Published by Elsevier B.V. All rights reserved.

  5. High-performance computing on the Intel Xeon Phi how to fully exploit MIC architectures

    CERN Document Server

    Wang, Endong; Shen, Bo; Zhang, Guangyong; Lu, Xiaowei; Wu, Qing; Wang, Yajuan

    2014-01-01

    The aim of this book is to explain to high-performance computing (HPC) developers how to utilize the Intel® Xeon Phi™ series products efficiently. To that end, it introduces some computing grammar, programming technology and optimization methods for using many-integrated-core (MIC) platforms and also offers tips and tricks for actual use, based on the authors' first-hand optimization experience.The material is organized in three sections. The first section, "Basics of MIC", introduces the fundamentals of MIC architecture and programming, including the specific Intel MIC programming environment

  6. Prevention for possible microbiologically influenced corrosion (MIC) in RHLWE flush water system

    International Nuclear Information System (INIS)

    Hsu, T.C.; Jenkins, C.F.

    1995-01-01

    This report is in response to the request to provide a recommendation for the prevention of possible microbiologically influenced corrosion (MIC) for the RHLWE (Replacement High-Level Waste Evaporator) flush water (FW) system. The recent occurrences of MIC at DWPF prompted HLWE to evaluate the possibility of MIC occurring in this 304L stainless steel RHLWE flush water system. Concern was heightened by the fact that the well water used and the other conditions at H-Tank Farm are similar to those at DWPF. However, only one known leak has occurred in the existing 304L evaporator flush water systems in either tank farm (in 1H system), and no MIC Corrosion has been confirmed in the tank farm area. The design of the RHLWE flush water system (completed long before the occurrence of MIC at DWPF) was modeled after the existing evaporator flush water systems and did not specifically include MIC prevention considerations. Therefore, MIC prevention was not specifically considered during the design phase of this flush water system. The system is presently being installed. After an extensive evaluation, a task team concluded that the best biocide to prevent the occurrence of MIC would be NaOH at fairly low concentration. Sodium hydroxide (NaOH) is optimal in this application, because of its effectiveness, low cost, and familiarity to the Operations personnel (see Appendix A). However, it is the opinion of the task group that application should be withheld until MIC corrosion is demonstrated in the system

  7. Anti-MIC2 as a tool in examination of testicular biopsies

    DEFF Research Database (Denmark)

    Visfeldt, J; Cortes, D; Thorup, J M

    1999-01-01

    MIC2 is a pseudoautosomal gene localized on X and Y chromosomes. The MIC2 gene product is a glycoprotein expressed on the cell membranes of a number of somatic cells, including Sertoli cells of the testis, but not on the cell membranes of germ cells. In cases of cryptorchidism, a testicular biopsy...... testes which had been cultured in vitro for 7, 14 or 21 days. In all cases the immunohistochemical method with DAKO antibody to the MIC2 gene product was helpful for identification of Sertoli cells and germ cells, and we therefore recommend the use of anti-MIC2 in all testicular biopsies where...

  8. Mic it! microphones, microphone techniques, and their impact on the final mix

    CERN Document Server

    Corbett, Ian

    2014-01-01

    Capture great sound in the first place, and spend less time ""fixing it in the mix"" with Ian Corbett's Mic It! Microphones, Microphone Techniques, and Their Impact on the Final Mix. With his expert guidance, you'll quickly understand essential audio concepts as they relate to microphones and mic techniques, and learn how to apply them to your recording situation. Whether you only ever buy one microphone, are equipping a studio on a budget, or have a vast selection of great mics to use, you'll learn to better use whatever tools you have. Mic It! gives you the background to design and discover

  9. An accelerated electrochemical MIC test for stainless alloys

    International Nuclear Information System (INIS)

    Gendron, T.S.; Cleland, R.D.

    1994-11-01

    Previous work in our laboratory and elsewhere has suggested that microbially influenced corrosion (MIC) of stainless steels and nickel-base alloys occurs in locally anaerobic regions that support the growth of sulfate-reducing bacteria (SRB). The cathodic reaction is provided by oxygen reduction at remote sites. Such a coupling between anode and cathode is difficult to reproduce in the laboratory, but can be simulated indirectly using a double electrochemical cell, as in previous work. A more realistic simulation using a single aerated electrochemical cell has now been developed, in which a second organism (P. aeruginosa) is used to provide an anoxic habitat for SRB growth and possible a source of organic carbon, within a layer of silt. A bare alloy electrode is used as the oxygen cathode. Tests of this kind using rigorous microbiological procedures have generated pitting corrosion of several alloys in low chloride media simulating freshwater heat exchanger conditions. This report discusses the adaption of these procedures to study corrosion of nuclear waste containers. (author). 20 refs., 2 tabs., 7 figs

  10. ENVIRONMENTALLY BENIGN MITIGATION OF MICROBIOLOGICALLY INFLUENCED CORROSION (MIC)

    Energy Technology Data Exchange (ETDEWEB)

    John J. Kilbane II; William Bogan

    2004-01-31

    The overall program objective is to develop and evaluate environmentally benign agents or products that are effective in the prevention, inhibition, and mitigation of microbially influenced corrosion (MIC) in the internal surfaces of metallic natural gas pipelines. The goal is to develop one or more environmentally benign (a.k.a. ''green'') products that can be applied to maintain the structure and dependability of the natural gas infrastructure. The technical approach for this quarter included the fractionation of extracts prepared from several varieties of pepper plants, and using several solvents, by high performance liquid chromatography (HPLC). A preliminary determination of antimicrobial activities of the new extracts and fractions using a growth inhibition assay, and evaluation of the extracts ability to inhibit biofilm formation was also performed. The analysis of multiple extracts of pepper plants and fractions of extracts of pepper plants obtained by HPLC illustrated that these extracts and fractions are extremely complex mixtures of chemicals. Gas chromatography-mass spectrometry was used to identify the chemical constituents of these extracts and fractions to the greatest degree possible. Analysis of the chemical composition of various extracts of pepper plants has illustrated the complexity of the chemical mixtures present, and while additional work will be performed to further characterize the extracts to identify bioactive compounds the focus of efforts should now shift to an evaluation of the ability of extracts to inhibit corrosion in mixed culture biofilms, and in pure cultures of bacterial types which are known or believed to be important in corrosion.

  11. ENVIROMENTALLY BENIGN MITIGATION OF MICROBIOLOGICALLY INFLUENCED CORROSION (MIC)

    Energy Technology Data Exchange (ETDEWEB)

    J. Robert Paterek; Gemma Husmillo; Amrutha Daram; Vesna Trbovic

    2003-10-31

    The overall program objective is to develop and evaluate environmentally benign agents or products that are effective in the prevention, inhibition, and mitigation of microbially influenced corrosion (MIC) in the internal surfaces of metallic natural gas pipelines. The goal is to develop one or more environmentally benign (a.k.a. ''green'') products that can be applied to maintain the structure and dependability of the natural gas infrastructure. The technical approach for this quarter includes the application of the method of fractionation of the extracts by high performance liquid chromatography (HPLC); determination of antimicrobial activities of the new extracts and fractions using a growth inhibition assay, and evaluation of the extracts' ability to inhibit biofilm formation. We initiated the delivery system for these new biocides in the test cell and in mixtures of foam components and biocides/anti-biofilms. A total of 51 fractions collected by HPLC from crude extracts that were obtained from three varieties of Capsicum sp. (Serrano, Habanero, Chile de Arbol) were subjected to growth inhibition tests against two SRB strains, D. vulgaris and D. desulfuricans. Five fractions showed growth inhibition against both strains while seven inhibited D. desulfuricans only. The crude extracts did not show growth inhibition on both strains but were proven to be potent in preventing the formation of biofilm. Growth inhibition tests of the same set of crude extracts against Comamonas denitrificans did not show positive results. The fractions will be subjected to biofilm inhibition and dissociation assay as well. The delivery system to be evaluated first was foam. The ''foam pig'' components of surfactants and water were tested with the biocide addition. The first chemical and physical parameters to be tested were pH and surfactants. Tests using the fractionated pepper extracts are progressing rapidly. Gas chromatographic analysis

  12. Immune protection of microneme 7 (EmMIC7) against Eimeria maxima challenge in chickens.

    Science.gov (United States)

    Huang, Jingwei; Zhang, Zhenchao; Li, Menghui; Song, Xiaokai; Yan, Ruofeng; Xu, Lixin; Li, Xiangrui

    2015-10-01

    In the present study, the immune protective effects of recombinant microneme protein 7 of Eimeria maxima (rEmMIC7) and a DNA vaccine encoding this antigen (pVAX1-EmMIC7) on experimental challenge were evaluated. Two-week-old chickens were randomly divided into five groups. Experimental groups of chickens were immunized with 100 μg DNA vaccine pVAX1-MIC7 or 200 μg rEmMIC7, while control groups of chickens were injected with pVAX1 plasmid or sterile phosphate buffered saline (PBS). The results showed that the anti-EmMIC7 antibody titres in chickens of both rEmMIC7 and pVAX1-MIC7 groups were significantly higher as compared to PBS and pVAX1 control (P maxima challenge in chickens and it could be an effective antigen candidate for the development of new vaccines against E. maxima.

  13. Support for higher ciprofloxacin AUC 24/MIC targets in treating Enterobacteriaceae bloodstream infection.

    Science.gov (United States)

    Zelenitsky, Sheryl A; Ariano, Robert E

    2010-08-01

    Given concerns regarding optimal therapy for serious Gram-negative infections, the goal was to characterize the pharmacodynamics of ciprofloxacin in the context of treating bloodstream infection. Data were collected from the medical records of 178 clinical cases. Blood isolates were retrieved and ciprofloxacin MICs were measured. Forty-two cases in which ciprofloxacin was initiated within 24 h of the positive blood culture were used in the pharmacodynamic analysis. Significant factors with regard to treatment failure were low ciprofloxacin AUC(24)/MIC (P AUC(24) (P = 0.01). AUC(24)/MIC (P = 0.012) and MIC (P = 0.019) were significant variables in multivariate analyses; however, only the former remained significant (P = 0.038) after excluding two cases with ciprofloxacin-resistant isolates. An AUC(24)/MIC breakpoint of 250 was most significant, with cure rates of 91.4% (32/35) and 28.6% (2/7) in patients with values above and below this threshold, respectively (P = 0.001). The risk of ciprofloxacin treatment failure was 27.8 times (95% confidence interval, 2.1-333) greater in those not achieving an AUC(24)/MIC >or=250 (P = 0.011). Monte Carlo simulation of 5000 study subjects predicted that 0.88 of the population would achieve an AUC(24)/MIC >or=250 with standard-dose ciprofloxacin (400 mg intravenously every 12 h). This study confirms the pharmacodynamic parameters of ciprofloxacin that are important for optimizing the treatment of serious infections, particularly the benefits of achieving an AUC(24)/MIC >or=250, rather than the conventional target of >or=125. It also shows the relevance of dose selection in optimizing target attainment, with important differences among pathogens, even those with MICs within the susceptible range.

  14. Vancomycin AUC/MIC and Corresponding Troughs in a Pediatric Population.

    Science.gov (United States)

    Kishk, Omayma A; Lardieri, Allison B; Heil, Emily L; Morgan, Jill A

    2017-01-01

    Adult guidelines suggest an area under the curve/minimum inhibitory concentration (AUC/MIC) > 400 corresponds to a vancomycin trough serum concentration of 15 to 20 mg/L for methicillin-resistant Staphylococcus aureus infections, but obtaining these troughs in children are difficult. The primary objective of this study was to assess the likelihood that 15 mg/kg of vancomycin every 6 hours in a child achieves an AUC/MIC > 400. This retrospective chart review included pediatric patients >2 months to AUCs were calculated four times using three pharmacokinetic methods. A total of 36 patients with 99 vancomycin trough serum concentrations were assessed. Baseline characteristics were similar between groups. For troughs in group 1 (n = 55), the probability of achieving an AUC/MIC > 400 ranged from 16.4% to 90.9% with a median trough concentration of 11.4 mg/L, while in group 2 (n = 44) the probability of achieving AUC/MIC > 400 ranged from 15.9% to 54.5% with mean trough concentration of 9.2 mg/L. The AUC/MICs were not similar between the different pharmacokinetic methods used; however, a trapezoidal equation (Method A) yielded the highest correlation coefficient (r 2 = 0.59). When dosing every 6 hours, an AUC/MIC of 400 correlated to a trough serum concentration of 11 mg/L. The probability of achieving an AUC/MIC > 400 using only a trough serum concentration and an MIC with patients receiving 15 mg/kg every 6 hours is variable based on the method used to calculate the AUC. An AUC/MIC of 400 in children correlated to a trough concentration of 11 mg/L using a trapezoidal Method to calculate AUC.

  15. LDL electronegativa: caracterització fisico-química i biològica en individus normolipèmics i hipercolesterolèmics

    OpenAIRE

    Benítez i Gonzàlez, Sònia

    2002-01-01

    Consultable des del TDX Títol obtingut de la portada digitalitzada L'LDL electronegativa (LDL(-)) és una fracció modificada de l'LDL total present en circulació. Vàries evidències indiquen que l'LDL(-) pot presentar característiques aterogèniques, ja que se suggereix que podria estar mínimament oxidada. En la present tesi s'han estudiat les propietats de l'LDL(-) procedent d'individus normolipèmics (NL) i hipercolesterolèmics (HF). Es van avaluar els següents aspectes: 1) Característiqu...

  16. Anti-MIC2 as a tool in examination of testicular biopsies

    DEFF Research Database (Denmark)

    Visfeldt, J; Cortes, Dina; Thorup, J M

    1999-01-01

    MIC2 is a pseudoautosomal gene localized on X and Y chromosomes. The MIC2 gene product is a glycoprotein expressed on the cell membranes of a number of somatic cells, including Sertoli cells of the testis, but not on the cell membranes of germ cells. In cases of cryptorchidism, a testicular biopsy...... transverse section is lower than 1% of the lowest normal age-matched value. Besides Sertoli cells the seminiferous tubules in undescended testes contain only a few germ cells, and it may be difficult to pinpoint the germ cells in small biopsies. Especially in nonpalpable testes their number may be heavily...... reduced. A reliable identification of germ cells may also be difficult in cultures of testicular biopsies from undescended testes. Against this background, we tried the use of an immunohistochemical method with DAKO antibody to the MIC2 gene product (MIC2, 12 E7, code no. M3601) in order to obtain...

  17. Imagen popular de la ciencia transmitida por los cómics

    OpenAIRE

    Gallego Torres, Adriana Patricia

    2007-01-01

    In this work we will be centered in the critical analysis of the popular image of the science transmitted by cómics existing in the market (in the measurement that makes reference to the scientific work).

  18. Guidelines for destructive examination of potential MIC [microbiologically influenced corrosion]-related failures

    International Nuclear Information System (INIS)

    Borenstein, S.S.

    1989-01-01

    Microbiologically influenced corrosion (MIC) is recognized as a major cause of pitting corrosion failures in natural waters. In order to alleviate the problem, it is important to establish the exact cause of corrosion. If there is a possibility that the failure is due to MIC, a particularly careful failure analysis must be conducted. MIC can be misdiagnosed as attack due to conventional chloride crevice/pitting corrosion unless specialized techniques are used. Certain techniques generally must be employed, including a careful visual examination, is situ bacterial sampling of residual water, bacterial analysis for corrosion products, radiographic examinations, and metallographic examinations. Other techniques may be necessary, or may be very helpful in the analysis, including culture growth, scanning electron microscopy, and ultrasonic examinations. Metallographic examinations can reveal MIC characteristics such as selective pitting of one phase in duplex stainless steel weldments. The methods of failure analysis and their importance are addressed, including each of the steps in the nondestructive examinations and destructive analyses

  19. Balancing vancomycin efficacy and nephrotoxicity: should we be aiming for trough or AUC/MIC?

    Science.gov (United States)

    Patel, Karisma; Crumby, Ashley S; Maples, Holly D

    2015-04-01

    Sixty years later, the question that still remains is how to appropriately utilize vancomycin in the pediatric population. The Infectious Diseases Society of America published guidelines in 2011 that provide guidance for dosing and monitoring of vancomycin in adults and pediatrics. However, goal vancomycin trough concentrations of 15-20 μg/mL for invasive infections caused by methicillin-resistant Staphylococcus aureus were based primarily on adult pharmacokinetic and pharmacodynamic data that achieved an area under the curve to minimum inhibitory concentration ratio (AUC/MIC) of ≥400. Recent pediatric literature shows that vancomycin trough concentrations needed to achieve the target AUC/MIC are different than the adult goal troughs cited in the guidelines. This paper addresses several thoughts, including the role of vancomycin AUC/MIC in dosing strategies and safety monitoring, consistency in laboratory reporting, and future directions for calculating AUC/MIC in pediatrics.

  20. Expanding Banking Services to Micro, Small and Medium Enterprises and Poor Households in the Philippines

    OpenAIRE

    Lamberte, Mario B.

    2001-01-01

    This paper has reviewed existing policies and programs to encourage banks to expand their financial services to micro, small- and medium-sized enterprises (MicSMEs) and poor households. The overall policy environment for promoting microfinance in the Philippines has indeed considerably improved since 1990, and there are signs that banks have favorably responded to it. However, banks still face some constraints in expanding further their financial services to MicSMEs and poor households. This ...

  1. General technique for the integration of MIC/MMIC'S with waveguides

    Science.gov (United States)

    Geller, Bernard D. (Inventor); Zaghloul, Amir I. (Inventor)

    1987-01-01

    A technique for packaging and integrating of a microwave integrated circuit (MIC) or monolithic microwave integrated circuit (MMIC) with a waveguide uses a printed conductive circuit pattern on a dielectric substrate to transform impedance and mode of propagation between the MIC/MMIC and the waveguide. The virtually coplanar circuit pattern lies on an equipotential surface within the waveguide and therefore makes possible single or dual polarized mode structures.

  2. MIC risk in the Halfdan oil export system quantified with a DNA-based diagnostic tool

    Energy Technology Data Exchange (ETDEWEB)

    Larsen, Jan; Rasmussen, Kim; Andersen, Kenneth [Maersk Oil (Denmark); Holmkvist, Lars [DTI Oil and Gas (Denmark)

    2011-07-01

    The paper presents the risk involved due to microbial influenced corrosion (MIC) using the halfdan oil export system. With growth of assets, scale and microbial fouling, corrosion and souring have increased. Some of the consequences to operators include, safety issues and loss of production. An example of the effects caused by MIC is the Valhall platform in the Norwegian sector, which was shut down for 80 days. Some of the factors causing bacterial growth and MIC are O2, CO2, and H2S, solids. Consideration of four objectives, corrosive products, microbiological activities, microbes, and spatially associating microbes is very important for diagnosing MIC. The objective of the halfdan study was to investigate the corrosion mechanism in the oil export spool section. Observations show severe pitting inside the pipelines. Suggestions for the operator, including the risk assessment of MIC, are given along with a summary of results. It can be concluded that there is a certain need in the industry to understand and act upon MIC.

  3. Employing the effective medium approximation to model the optical properties of crystallized a-Si:H obtained by MIC

    NARCIS (Netherlands)

    Muller, T.F.G.; Knoesen, D.|info:eu-repo/dai/nl/304845841; Arendse, C.J.; Halindintwali, S.; Malgas, G.F.; Houweling, Z.S.|info:eu-repo/dai/nl/251874486; Schropp, R.E.I.|info:eu-repo/dai/nl/072502584

    2010-01-01

    Metal induced crystallization of hydrogenated amorphous silicon has been the subject of intense scrutiny in recent years. In this contribution we report on the metal-mediated-thermally induced changes of the structural and optical properties of hydrogenated amorphous silicon deposited by hot-wire

  4. A Novel and Validated Protocol for Performing MIC Tests to Determine the Susceptibility of Piscirickettsia salmonis Isolates to Florfenicol and Oxytetracycline

    Directory of Open Access Journals (Sweden)

    Sergio Contreras-Lynch

    2017-07-01

    Full Text Available This paper presents a validated protocol, using a novel, specifically formulated medium, to perform broth microdilution antimicrobial susceptibility assays of the salmonid bacterial pathogen Piscirickettsia salmonis. The minimum inhibitory concentrations (MIC for florfenicol and oxytetracycline against 58 P. salmonis isolates recovered from various outbreaks occurred in Chilean salmonid farms were determined using this protocol. Normalized resistance interpretation (NRI analysis was applied to these data to calculate appropriate protocol-specific epidemiological cut-off values. These cut-off values allow the isolates to be categorized as either fully susceptible wild type (WT members of this species, or as manifesting reduced susceptibility non-wild type (NWT. The distribution of MIC values of florfenicol was bimodal and the distribution of the normalized values for the putative WT observation had a standard deviation of 0.896 log2 μg mL-1. This analysis calculated a cut-off value of ≤0.25 μg mL-1 and categorized 33 (56% of the isolates as manifesting reduced susceptibility to florfenicol. For the oxytetracycline MIC data the NRI analysis also treated the distribution as bimodal. The distribution of the normalized values for the putative WT observation had a standard deviation of 0.951 log2 μg mL-1. This analysis gave a cut-off value of ≤0.5 μg mL-1 and categorized five isolates (9% as manifesting reduced susceptibility to oxytetracycline. The susceptibility testing protocol developed in this study was capable of generating MIC data from all the isolates tested. On the basis of the precision of the data it generated, and the degree of separation of values for WT and NWT it achieved, it is argued that this protocol has the performance characteristics necessary for it to be considered as a standard protocol.

  5. Meio semiseletivo para recuperação e quantificação de Cryptosporiopsis perennans em maçãs Semi-selective medium for recovery and quantification of Cryptosporiopsis perennans from apple fruits

    Directory of Open Access Journals (Sweden)

    Piérri Spolti

    2010-03-01

    Full Text Available A podridão "olho de boi", causada pelo fungo Cryptosporiopsis perennans, é uma das doenças de pós-colheita da macieira mais importantes no Brasil. Os objetivos deste trabalho foram desenvolver e avaliar um meio semiseletivo para a recuperação e mensuração da população epífita de C. perennans em maçãs "Fuji". A suplementação de BDA com tetraciclina, nistatina e iprodiona, nas respectivas concentrações de 12,5; 1 e 1µg p.a mL-1, proporcionou o desenvolvimento de colônias de C. perennans estatisticamente igual (P>0,05 ao observado no meio BDA. Em condições de infecção natural e em amostras pré-inoculadas com C. perennans, o meio semiseletivo permitiu detectar e quantificar a população do fungo na superfície dos frutos, além de ter inibido o crescimento de fungos leveduriformes, dematiáceos e leveduras. Em lavagens de frutos previamente inoculados, o número de conídios recuperados com o meio semiseletivo apresentou correlação (r=0,88; PBull's eye rot, caused by Cryptosporiopsis perennans, is one of the most important apple's posharvest diseases in Brazil. The aim of this research was to develop and evaluate a semi-selective media to recovery and quantification of the epiphytic population of C. perennans on the apple fruit surface. A PDA medium amended with tetracycline, nistatine and iprodione in concentrations of 12.5; 1 and 1µg i.a.mL-1, respectively, allowed the development of C. perennans colonies statistically similar (P>0.05 to those in PDA media. Nistatine concentrations higher than 1µg.mL-1 inhibited the growth of the pathogen. Under natural infection conditions and pre-inoculation with C. perennans, the media allowed the detection and quantification of the fungal population on the fruit surface without affecting C. perennans development. Number of conidia observed in pre-inoculated fruits was correlated (r=0.88; P<0.05 to inoculum concentration sprayed on the fruit surface.

  6. Analysis of the Sarcocystis neurona microneme protein SnMIC10: protein characteristics and expression during intracellular development.

    Science.gov (United States)

    Hoane, Jessica S; Carruthers, Vernon B; Striepen, Boris; Morrison, David P; Entzeroth, Rolf; Howe, Daniel K

    2003-07-01

    Sarcocystis neurona, an apicomplexan parasite, is the primary causative agent of equine protozoal myeloencephalitis. Like other members of the Apicomplexa, S. neurona zoites possess secretory organelles that contain proteins necessary for host cell invasion and intracellular survival. From a collection of S. neurona expressed sequence tags, we identified a sequence encoding a putative microneme protein based on similarity to Toxoplasma gondii MIC10 (TgMIC10). Pairwise sequence alignments of SnMIC10 to TgMIC10 and NcMIC10 from Neospora caninum revealed approximately 33% identity to both orthologues. The open reading frame of the S. neurona gene encodes a 255 amino acid protein with a predicted 39-residue signal peptide. Like TgMIC10 and NcMIC10, SnMIC10 is predicted to be hydrophilic, highly alpha-helical in structure, and devoid of identifiable adhesive domains. Antibodies raised against recombinant SnMIC10 recognised a protein band with an apparent molecular weight of 24 kDa in Western blots of S. neurona merozoites, consistent with the size predicted for SnMIC10. In vitro secretion assays demonstrated that this protein is secreted by extracellular merozoites in a temperature-dependent manner. Indirect immunofluorescence analysis of SnMIC10 showed a polar labelling pattern, which is consistent with the apical position of the micronemes, and immunoelectron microscopy provided definitive localisation of the protein to these secretory organelles. Further analysis of SnMIC10 in intracellular parasites revealed that expression of this protein is temporally regulated during endopolygeny, supporting the view that micronemes are only needed during host cell invasion. Collectively, the data indicate that SnMIC10 is a microneme protein that is part of the excreted/secreted antigen fraction of S. neurona. Identification and characterisation of additional S. neurona microneme antigens and comparisons to orthologues in other Apicomplexa could provide further insight into the

  7. Traducción de cómic americano, superhéroes y chimichangas

    OpenAIRE

    Gonzalbes Valenzuela, Carla

    2015-01-01

    El objetivo de este trabajo es estudiar el proceso de traducción de un cómic americano. Consiste de una traducción de varios fragmentos de un cómic de Marvel de Masacre (Deadpool, en inglés) y un posterior análisis de dicha traducción, en el que se comentan los problemas que han surgido, se explica la solución al problema y se justifican las decisiones tomadas L'objectiu d'aquest treball és estudiar el procés de traducció d'un còmic americà. Consisteix en la traducció de diversos fragments...

  8. El cómic en España: 1977-2007

    Directory of Open Access Journals (Sweden)

    Pablo Vergara Díaz

    2009-07-01

    Full Text Available Este artículo pretende repasar las tres últimas décadas del cómic en España. El estudio se realiza valorando la evolución de la industria del cómic, desde sus inicios durante la dictadura y su expansión con la llegada de la democracia hasta la época actual de dificultades y cambios. El auge del cómic se observa en su relevancia creciente dentro de la prensa, en la aceptación de un público que va madurando con el paso del tiempo y, sobre todo, en las ventas de una industria que tiene que adaptarse a nuevas situaciones.

  9. En el umbral. El cómic español contemporáneo

    Directory of Open Access Journals (Sweden)

    García, Santiago

    2011-09-01

    Full Text Available These days, when we talk about contemporary Spanish comics, or comics produced primarily in Spain for the Spanish market, we have to contemplate two main trends: the graphic novel and the humor comics. The fall of the traditional industry opened the door to the realization of authoral ambitions that previous generations of artists couldn’t fulfil.

    En la actualidad, cuando hablamos de cómic español contemporáneo, es decir, cuando nos referimos a cómics producidos en España y para el mercado español en primer lugar, tenemos que tener en cuenta dos corrientes principalmente: la novela gráfica y el cómic de humor. La caída de la industria tradicional ha abierto el camino para que se cumplan las aspiraciones autorales que durante décadas tuvieron muchos dibujantes españoles.

  10. Is There an Opportunity for Current Chemotherapeutics to Up-regulate MIC-A/B Ligands?

    Directory of Open Access Journals (Sweden)

    Kendel Quirk

    2017-10-01

    Full Text Available Natural killer (NK cells are critical effectors of the immune system. NK cells recognize unhealthy cells by specific ligands [e.g., MHC- class I chain related protein A or B (MIC-A/B] for further elimination by cytotoxicity. Paradoxically, cancer cells down-regulate MIC-A/B and evade NK cell’s anticancer activity. Recent data indicate that cellular-stress induces MIC-A/B, leading to enhanced sensitivity of cancer cells to NK cell-mediated cytotoxicity. In this Perspective article, we hypothesize that current chemotherapeutics at sub-lethal, non-toxic dose may promote cellular-stress and up-regulate the expression of MIC-A/B ligands to augment cancer’s sensitivity to NK cell-mediated cytotoxicity. Preliminary data from two human breast cancer cell lines, MDA-MB-231 and T47D treated with clinically relevant therapeutics such as doxorubicin, paclitaxel and methotrexate support the hypothesis. The goal of this Perspective is to underscore the prospects of current chemotherapeutics in NK cell immunotherapy, and discuss potential challenges and opportunities to improve cancer therapy.

  11. MICs of Oxazolidinones for Rhodococcus equi Strains Isolated from Humans and Animals

    OpenAIRE

    Bowersock, Terry L.; Salmon, Sarah A.; Portis, Ellen S.; Prescott, John F.; Robison, Denise A.; Ford, Charles W.; Watts, Jeffrey L.

    2000-01-01

    Eperezolid and linezolid are representatives of a new class of orally active, synthetic antimicrobial agents. The in vitro activity values (MICs) of linezolid, eperezolid, and comparator antibiotics against 102 strains of Rhodococcus equi isolated from humans and animals were determined. Linezolid was more active than eperezolid against the strains tested; premafloxacin was the most active comparator antibiotic.

  12. Imagen popular de la ciencia transmitida por los cómics

    Directory of Open Access Journals (Sweden)

    Gallego, A.P.

    2007-01-01

    Full Text Available In this work we will be centered in the critical analysis of the popular image of the science transmitted by cómics existing in the market (in the measurement that makes reference to the scientific work.

  13. Imagen popular de la ciencia transmitida por los cómics

    Directory of Open Access Journals (Sweden)

    Adriana Patricia Gallego-Torres

    2007-01-01

    Full Text Available En este trabajo nos centraremos en el análisis crítico de la imagen popular de la ciencia transmitida por los cómics existentes en el mercado (en la medida que hagan referencia al trabajo científico.

  14. MiMIC: a highly versatile transposon insertion resource for engineering Drosophila melanogaster genes

    Science.gov (United States)

    Venken, Koen J. T.; Schulze, Karen L.; Haelterman, Nele A.; Pan, Hongling; He, Yuchun; Evans-Holm, Martha; Carlson, Joseph W.; Levis, Robert W.; Spradling, Allan C.; Hoskins, Roger A.; Bellen, Hugo J.

    2011-01-01

    We demonstrate the versatility of a collection of insertions of the transposon Minos mediated integration cassette (MiMIC), in Drosophila melanogaster. MiMIC contains a gene-trap cassette and the yellow+ marker flanked by two inverted bacteriophage ΦC31 attP sites. MiMIC integrates almost at random in the genome to create sites for DNA manipulation. The attP sites allow the replacement of the intervening sequence of the transposon with any other sequence through recombinase mediated cassette exchange (RMCE). We can revert insertions that function as gene traps and cause mutant phenotypes to wild type by RMCE and modify insertions to control GAL4 or QF overexpression systems or perform lineage analysis using the Flp system. Insertions within coding introns can be exchanged with protein-tag cassettes to create fusion proteins to follow protein expression and perform biochemical experiments. The applications of MiMIC vastly extend the Drosophila melanogaster toolkit. PMID:21985007

  15. [Comparison of four MICS intraocular lenses regarding their rates of neodymium:YAG laser capsulotomy].

    Science.gov (United States)

    Spyridaki, M; Höh, H

    2010-03-01

    The aim of this study was to evaluate the incidence of posterior capsule opacification up to 50 months following 1.7-mm bimanual MICS-cataract surgery. Bimanual MICS cataract surgery was performed in 197 eyes (135 patients) via two 1.7-mm corneal incisions. Four MICS acrylic foldable IOLs were implanted: AcriSmart 48S-5, n = 54 (Acritec GmbH, Hennigsdorf, now AT.Smart 48S Carl-Zeiss-Meditec, AG, Jena, Germany), ThinLens UltraChoice 1.0, n = 53 (Technomed GmbH, Baesweiler, Germany), AcriFlex 46, n = 41 und AcriFlex 48 CSE, n = 7 (Acrimed GmbH, Berlin, now: Lentis L-303, Oculentis GmbH, Berlin, Germany) and CareFlex, n = 43 (w2o Medizintechnik AG, Bruchsal, Germany). Statistical analysis was performed using the Kaplan-Meier technique. High levels of completeness of follow-up rates were: ThinLens 96%, CareFlex 100%, AcriSmart 93%, AcriFlex 92%. The capsulotomy rate was 43.13% for ThinLens within a mean/max. follow-up period of 801/1131 days, 34.88% for CareFlex (565/872 days), 40% for AcriSmart (988/1506 days) and 15.91% for AcriFlex (728/975 days). By limiting the follow-up period to a comparable maximum of 850 days for all four IOLs, our capsulotomy rates were as follows: ThinLens 33.33%, CareFlex 32.56 %, AcriSmart 20.0% and AcriFlex 11.36%. MICS IOLs have higher capsulotomy rates than hydrophobic acrylic lenses and sharp-edged silicone lenses. In literature comparisons MICS-IOLs do not exceed the variance levels of capsulotomy rates of PMMA, hydrophilic acrylic and silicone lenses without sharp edges. Cases of decentration or luxation of MICS-IOLs following Neodym:YAG laser capsulotomy were not detected. Capsulotomy frequency with the CareFlex was statistically significantly higher in comparison to the AcriSmart (Log Rank Mantel Cox Test, p = 0.007) and AcriFlex (log rank Mantel Cox test, p = 0.002). Capsulotomy rates observed varied for the four MICS-IOL-types tested. The posterior capsule opacification frequency of the two best MICS-IOLs (AcriFlex, Acri

  16. Discrepancy in Vancomycin AUC/MIC Ratio Targeted Attainment Based upon the Susceptibility Testing in Staphylococcus aureus.

    Science.gov (United States)

    Eum, Seenae; Bergsbaken, Robert L; Harvey, Craig L; Warren, J Bryan; Rotschafer, John C

    2016-09-27

    This study demonstrated a statistically significant difference in vancomycin minimum inhibitory concentration (MIC) for Staphylococcus aureus between a common automated system (Vitek 2) and the E-test method in patients with S. aureus bloodstream infections. At an area under the serum concentration time curve (AUC) threshold of 400 mg∙h/L, we would have reached the current Infectious Diseases Society of America (IDSA)/American Society of Health System Pharmacists (ASHP)/Society of Infectious Diseases Pharmacists (SIDP) guideline suggested AUC/MIC target in almost 100% of patients while using the Vitek 2 MIC data; however, we could only generate 40% target attainment while using E-test MIC data ( p AUC of 450 mg∙h/L or greater was required to achieve 100% target attainment using either Vitek 2 or E-test MIC results.

  17. Department of Energy: MICS (Mathematical Information, and Computational Sciences Division). High performance computing and communications program

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-06-01

    This document is intended to serve two purposes. Its first purpose is that of a program status report of the considerable progress that the Department of Energy (DOE) has made since 1993, the time of the last such report (DOE/ER-0536, {open_quotes}The DOE Program in HPCC{close_quotes}), toward achieving the goals of the High Performance Computing and Communications (HPCC) Program. The second purpose is that of a summary report of the many research programs administered by the Mathematical, Information, and Computational Sciences (MICS) Division of the Office of Energy Research under the auspices of the HPCC Program and to provide, wherever relevant, easy access to pertinent information about MICS-Division activities via universal resource locators (URLs) on the World Wide Web (WWW). The information pointed to by the URL is updated frequently, and the interested reader is urged to access the WWW for the latest information.

  18. [Effectiveness of Mitral Natural Folding Plasty for Minimally Invasive Cardiac Surgery Mitral Valve Plasty (MICS MVP)].

    Science.gov (United States)

    Kondo, Shunichi; Tsuboi, Eitoshi; Rokkaku, Kyu; Irie, Yoshihito; Yokoyama, Hitoshi

    2015-01-01

    We performed 45 cases of Natural folding plasty without leaflet resection for degenerative mitral regurgitation (MR) between September 2005 and July 2014. Twenty cases of 45 were operated by right small intercostal approach (MICS). There was no operative mortality. No patient had greater than mild MR intraoperative transesophageal echocardiography. The median follow-up was 847 (19~1,747) days. One case needed a second pump run performed without complication. One patient had a reoperation performed for recurrent MR 20 months later. Natural folding plasty for degenerative MR with favorable long term out come in our results. This technique is simple and reproducible for most surgeons. Furthermore, with its simplicity and reversibility, we considered it to be suitable for MICS approach.

  19. EL ESTADO DE LA CIENCIA. INVESTIGACIÓN Y CÓMIC

    Directory of Open Access Journals (Sweden)

    Michel Matly

    2017-03-01

    Full Text Available La investigación académica sobre el cómic español y latinoamericano es un mundo pequeño, sin memoria, poco organizado e insuficientemente conocido por sus propios miembros. Al contrario de otras disciplinas científicas, existe poca tradición de colaboración, pocas dinámicas de equipo o escuelas de pensamiento identificables como tal. La capitalización de su memoria se enfrenta a dificultades, unas externas, otras internas: los cómics antiguos y descatalogados no han sido conservados en un sistema coherente de bibliotecas y son de difícil acceso; casi no existen revistas indexadas donde publicar; los mismos trabajos científicos sobre el cómic están dispersos y sin indexar, complicando el trabajo de nuevos investigadores. El crecimiento durante estas últimas décadas de dicho sector de investigación abre nuevas oportunidades y a la vez crea nuevas obligaciones. El número creciente de investigadores abre más perspectivas para potenciar núcleos de pensamiento y desarrollar colaboraciones y competiciones, bases del avance científico. Estamos también a tiempo de organizar la bibliografía científica dedicada al cómic en español. En fin, la investigación debe aprender a desarrollar puentes entre los mundos académico y no académico, para encontrar cómo desarrollar una red de publicaciones científicas digitales y beneficiarse del importante trabajo de memoria realizado a través del mundo hispanista por comunidades de apasionados que recuperan y ponen a disposición de los interesados obras antiguas hasta ahora perdidas.

  20. micROS: a morphable, intelligent and collective robot operating system.

    Science.gov (United States)

    Yang, Xuejun; Dai, Huadong; Yi, Xiaodong; Wang, Yanzhen; Yang, Shaowu; Zhang, Bo; Wang, Zhiyuan; Zhou, Yun; Peng, Xuefeng

    2016-01-01

    Robots are developing in much the same way that personal computers did 40 years ago, and robot operating system is the critical basis. Current robot software is mainly designed for individual robots. We present in this paper the design of micROS, a morphable, intelligent and collective robot operating system for future collective and collaborative robots. We first present the architecture of micROS, including the distributed architecture for collective robot system as a whole and the layered architecture for every single node. We then present the design of autonomous behavior management based on the observe-orient-decide-act cognitive behavior model and the design of collective intelligence including collective perception, collective cognition, collective game and collective dynamics. We also give the design of morphable resource management, which first categorizes robot resources into physical, information, cognitive and social domains, and then achieve morphability based on self-adaptive software technology. We finally deploy micROS on NuBot football robots and achieve significant improvement in real-time performance.

  1. Multi-Kepler GPU vs. multi-Intel MIC for spin systems simulations

    Science.gov (United States)

    Bernaschi, M.; Bisson, M.; Salvadore, F.

    2014-10-01

    We present and compare the performances of two many-core architectures: the Nvidia Kepler and the Intel MIC both in a single system and in cluster configuration for the simulation of spin systems. As a benchmark we consider the time required to update a single spin of the 3D Heisenberg spin glass model by using the Over-relaxation algorithm. We present data also for a traditional high-end multi-core architecture: the Intel Sandy Bridge. The results show that although on the two Intel architectures it is possible to use basically the same code, the performances of a Intel MIC change dramatically depending on (apparently) minor details. Another issue is that to obtain a reasonable scalability with the Intel Phi coprocessor (Phi is the coprocessor that implements the MIC architecture) in a cluster configuration it is necessary to use the so-called offload mode which reduces the performances of the single system. As to the GPU, the Kepler architecture offers a clear advantage with respect to the previous Fermi architecture maintaining exactly the same source code. Scalability of the multi-GPU implementation remains very good by using the CPU as a communication co-processor of the GPU. All source codes are provided for inspection and for double-checking the results.

  2. Fast and efficient Drosophila melanogaster gene knock-ins using MiMIC transposons.

    Science.gov (United States)

    Vilain, Sven; Vanhauwaert, Roeland; Maes, Ine; Schoovaerts, Nils; Zhou, Lujia; Soukup, Sandra; da Cunha, Raquel; Lauwers, Elsa; Fiers, Mark; Verstreken, Patrik

    2014-10-08

    Modern molecular genetics studies necessitate the manipulation of genes in their endogenous locus, but most of the current methodologies require an inefficient donor-dependent homologous recombination step to locally modify the genome. Here we describe a methodology to efficiently generate Drosophila knock-in alleles by capitalizing on the availability of numerous genomic MiMIC transposon insertions carrying recombinogenic attP sites. Our methodology entails the efficient PhiC31-mediated integration of a recombination cassette flanked by unique I-SceI and/or I-CreI restriction enzyme sites into an attP-site. These restriction enzyme sites allow for double-strand break-mediated removal of unwanted flanking transposon sequences, while leaving the desired genomic modifications or recombination cassettes. As a proof-of-principle, we mutated LRRK, tau, and sky by using different MiMIC elements. We replaced 6 kb of genomic DNA encompassing the tau locus and 35 kb encompassing the sky locus with a recombination cassette that permits easy integration of DNA at these loci and we also generated a functional LRRK(HA) knock in allele. Given that ~92% of the Drosophila genes are located within the vicinity (MiMIC element, our methodology enables the efficient manipulation of nearly every locus in the fruit fly genome without the need for inefficient donor-dependent homologous recombination events. Copyright © 2014 Vilain et al.

  3. Disaster Debris Recovery Database - Recovery

    Data.gov (United States)

    U.S. Environmental Protection Agency — The US EPA Disaster Debris Recovery Database (DDRD) promotes the proper recovery, recycling, and disposal of disaster debris for emergency responders at the federal,...

  4. Single-Event Latchup Testing of the Micrel MIC4424 Dual Power MOSFET Driver

    Science.gov (United States)

    Pellish, J. A.; Boutte, A.; Kim, H.; Phan, A.; Topper, A.

    2016-01-01

    We conducted 47 exposures of four different MIC4424 devices and did not observe any SEL or high-current events. This included worst-case conditions with a LET of 81 MeV-sq cm/mg, applied voltage of 18.5 V, a case temperature greater than 120 C, and a final fluence of 1x10(exp 7)/sq cm. We also monitored both the outputs for the presence of SETs. While the period of the 1 MHz square wave was slightly altered in some cases, no pulses were added or deleted. 1. Purpose: The purpose of this testing is to characterize the BiCMOS/DMOS Micrel MIC4424 dual, non-inverting MOSFET driver for single-event latchup (SEL) susceptibility. These data will be used for flight lot evaluation purposes. 2. Devices Tested: The MIC4423/4424/4425 family are highly reliable BiCMOS/DMOS buffer/driver MOSFET drivers. They are higher output current versions of the MIC4426/4427/4428. They can survive up to 5V of noise spiking, of either polarity, on the ground pin. They can accept, without either damage or logic upset, up to half an amp of reverse current (either polarity) forced back into their outputs. Primarily intended for driving power MOSFETs, the MIC4423/4424/4425 drivers are suitable for driving other loads (capacitive, resistive, or inductive) which require low-impedance, high peak currents, and fast switching times. Heavily loaded clock lines, coaxial cables, or piezoelectric transducers are some examples. The only known limitation on loading is that total power dissipated in the driver must be kept within the maximum power dissipation limits of the package. Five (5) parts were provided for SEL testing. We prepared four parts for irradiation and reserved one piece as an un-irradiated control. More information about the devices can be found in Table 1. The parts were prepared for testing by removing the lid from the CDIP package to expose the target die. The parts were then soldered to small copper circuit adapter boards for easy handling. These parts are fabricated in a bulk Bi

  5. The need to assay the real MIC when making the decision to eradicate Staphylococcus aureus with vancomycin

    Directory of Open Access Journals (Sweden)

    Hanna Tomczak

    2013-09-01

    Full Text Available Purpose: The aim of the study was a comparison of the MIC (minimal inhibitory concentration evaluated in the automatic system Vitek 2 and the real MIC of vancomycin by the Etest method for S. aureus strains isolated from clinical materials.Material and Methods: Over a twelve-month study period we compared the results obtained with two commercial methods – the automatic system VITEK 2 and the real MIC by Etest – for 359 strains of S. aureus isolated from clinical materials.Results: Most of the strains of S. aureus were cultured from wounds (84, the ear (60 and nose (42. MSSA (methicillin-sensitive Staphylococcus aureus was isolated in 342 cases and MRSA (methicillin-resistant Staphylococcus aureus in 17 cases. The test with the Vitek automatic method showed that vancomycin had MIC values of ≤1.0 μg/ml in more than 96�0and 2.0 μg/ml in over 3�0of cases. Using the Etest technique MIC ≤ 1.0 μg/ml was obtained in only 16.4�0of cases and values of >1.0 μg/ml in 83.6�0of cases.Discussion: In view of such big differences between the MIC values obtained with the two methods the authors suggest that the Etest method of assaying the real MIC is more useful than the automatic method.

  6. Evaluation of vancomycin MIC creep in methicillin-resistant Staphylococcus aureus infections-a systematic review and meta-analysis.

    Science.gov (United States)

    Diaz, R; Afreixo, V; Ramalheira, E; Rodrigues, C; Gago, B

    2018-02-01

    Vancomycin is currently the primary option treatment for methicillin-resistant Staphylococcus aureus (MRSA). However, an increasing number of MRSA isolates with high MICs, within the susceptible range (vancomycin MIC creep), are being reported worldwide. Resorting to a meta-analysis approach, this study aims to assess the evidence of vancomycin MIC creep. We searched for studies in the PubMed database. The inclusion criteria for study eligibility included the possibility of retrieving the reported data values of vancomycin MIC and information concerning the applied MIC methodology. The mean values of vancomycin MICs, of all 29 234 S. aureus isolates reported in the 55 studies included in the meta-analysis, were 1.23 mg/L (95% CI 1.13-1.33) and 1.20 mg/L (95% CI 1.13-1.28) determined by Etest and broth microdilution method, respectively. No significant differences were observed between these two methodologies. We found negative correlation between pooled mean/pooled proportion and time strata. We have found no evidence of the MIC creep phenomenon. Copyright © 2017 European Society of Clinical Microbiology and Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

  7. An investigation of microbial diversity in crude oil & seawater injection systems and microbiologically influenced corrosion (MIC) of linepipe steels under different exposure conditions

    Science.gov (United States)

    AlAbbas, Faisal Mohammed

    reduced the biocorrosion rate by approximately 50%. Neem significantly reduced the contribution of SRB in the corrosion process by minimizing the growth of cells, which subsequently suppressed the production of sulfide, density of sessile cells and development of biofilm. Moreover, the Neem extracts might provide an organic coating that protects the surface against the medium. The work provided by this research will expand the MIC knowledge within the oil and gas industry and will improve monitoring and prevention strategies and direct future research of MIC-related issues, such as microbial injection inhibitors aided with magnetic fields applications and environmentally friendly biocides.

  8. Macrophage inhibitory cytokine-1 (MIC-1/GDF15 slows cancer development but increases metastases in TRAMP prostate cancer prone mice.

    Directory of Open Access Journals (Sweden)

    Yasmin Husaini

    Full Text Available Macrophage inhibitory cytokine-1 (MIC-1/GDF15, a divergent member of the TGF-β superfamily, is over-expressed by many common cancers including those of the prostate (PCa and its expression is linked to cancer outcome. We have evaluated the effect of MIC-1/GDF15 overexpression on PCa development and spread in the TRAMP transgenic model of spontaneous prostate cancer. TRAMP mice were crossed with MIC-1/GDF15 overexpressing mice (MIC-1(fms to produce syngeneic TRAMP(fmsmic-1 mice. Survival rate, prostate tumor size, histopathological grades and extent of distant organ metastases were compared. Metastasis of TC1-T5, an androgen independent TRAMP cell line that lacks MIC-1/GDF15 expression, was compared by injecting intravenously into MIC-1(fms and syngeneic C57BL/6 mice. Whilst TRAMP(fmsmic-1 survived on average 7.4 weeks longer, had significantly smaller genitourinary (GU tumors and lower PCa histopathological grades than TRAMP mice, more of these mice developed distant organ metastases. Additionally, a higher number of TC1-T5 lung tumor colonies were observed in MIC-1(fms mice than syngeneic WT C57BL/6 mice. Our studies strongly suggest that MIC-1/GDF15 has complex actions on tumor behavior: it limits local tumor growth but may with advancing disease, promote metastases. As MIC-1/GDF15 is induced by all cancer treatments and metastasis is the major cause of cancer treatment failure and cancer deaths, these results, if applicable to humans, may have a direct impact on patient care.

  9. Development of biological coal gasification (MicGAS process). Final report, May 1, 1990--May 31, 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-12-31

    ARCTECH has developed a novel process (MicGAS) for direct, anaerobic biomethanation of coals. Biomethanation potential of coals of different ranks (Anthracite, bitumious, sub-bitumious, and lignites of different types), by various microbial consortia, was investigated. Studies on biogasification of Texas Lignite (TxL) were conducted with a proprietary microbial consortium, Mic-1, isolated from hind guts of soil eating termites (Zootermopsis and Nasutitermes sp.) and further improved at ARCTECH. Various microbial populations of the Mic-1 consortium carry out the multi-step MicGAS Process. First, the primary coal degraders, or hydrolytic microbes, degrade the coal to high molecular weight (MW) compounds. Then acedogens ferment the high MW compounds to low MW volatile fatty acids. The volatile fatty acids are converted to acetate by acetogens, and the methanogens complete the biomethanation by converting acetate and CO{sub 2} to methane.

  10. Application of natural antimicrobial compounds for reservoir souring and MIC prevention in offshore oil and gas production systems

    DEFF Research Database (Denmark)

    Thomsen, Mette Hedegaard; Skovhus, Torben Lund; Mashietti, Marco

    Offshore oil production facilities are subjectable to internal corrosion, potentially leading to human and environmental risk and significant economic losses. Microbiologically influenced corrosion (MIC) and reservoir souring - sulphide production by sulfate reducing microorganisms in the reservo...

  11. Antimycobacterial activity evaluation and MIC determination of liophilizated hydroalcoholic extracts of Bixa orellana L., Bixaceae

    Directory of Open Access Journals (Sweden)

    Renata B. Silva

    Full Text Available Bixa orellana is used in popular medicine against several diseases. Extracts of its fruit, root and leaf presented antimicrobial activity, while seed extract showed negative results. This study aimed at verifying the antimycobacterial activity of B. orellanalyophilized hydroalcoholic extracts over Mycobacterium tuberculosis, and determine the Minimum Inhibitory Concentration against five bacteria. Antimycobacterial activity was determined by diffusion technique, while MIC was assessed by diffusion and colorimetric analysis. MICs were 0.3, 0.5 and 0.2 mg/mL respectively, for leaf, root and stem extracts, against M. tuberculosis. Stem's extract showed 1.2 mg/mL for B. cereus, 1.53 mg/mL for S. aureusand S. typhimurium, 4.50 mg/mL for P. aeruginosaand 8.01 mg/mL for P. mirabillis.Leaf extracts showed 0.66 mg/mL for P. aeruginosa, 0.94 mg/mL for P. mirabillis, 1.88 mg/mL for S. aureus, 3.95 mg/mL for B. cereusand 8.37 mg/mL for S. typhimurium. Root's extracts showed 0.25 mg/mL for P. aeruginosa,0.31 mg/mL for S. aureus, 0.62 mg/mL for S. typhimuriumand 3.00 mg/mL for B. cereusand P. mirabillis. Leaf and stem extracts showed antimycobacterial activity. MICs were lower in colorimetric analysis than in agar diffusion. Extracts revealed bacteriostatic activity against the five bacterial.

  12. Thread-level parallelization and optimization of NWChem for the Intel MIC architecture

    Energy Technology Data Exchange (ETDEWEB)

    Shan, Hongzhang [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Williams, Samuel [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); de Jong, Wibe [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Oliker, Leonid [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2015-01-01

    In the multicore era it was possible to exploit the increase in on-chip parallelism by simply running multiple MPI processes per chip. Unfortunately, manycore processors' greatly increased thread- and data-level parallelism coupled with a reduced memory capacity demand an altogether different approach. In this paper we explore augmenting two NWChem modules, triples correction of the CCSD(T) and Fock matrix construction, with OpenMP in order that they might run efficiently on future manycore architectures. As the next NERSC machine will be a self-hosted Intel MIC (Xeon Phi) based supercomputer, we leverage an existing MIC testbed at NERSC to evaluate our experiments. In order to proxy the fact that future MIC machines will not have a host processor, we run all of our experiments in native mode. We found that while straightforward application of OpenMP to the deep loop nests associated with the tensor contractions of CCSD(T) was sufficient in attaining high performance, significant e ort was required to safely and efeciently thread the TEXAS integral package when constructing the Fock matrix. Ultimately, our new MPI+OpenMP hybrid implementations attain up to 65× better performance for the triples part of the CCSD(T) due in large part to the fact that the limited on-card memory limits the existing MPI implementation to a single process per card. Additionally, we obtain up to 1.6× better performance on Fock matrix constructions when compared with the best MPI implementations running multiple processes per card.

  13. Thread-Level Parallelization and Optimization of NWChem for the Intel MIC Architecture

    Energy Technology Data Exchange (ETDEWEB)

    Shan, Hongzhang; Williams, Samuel; Jong, Wibe de; Oliker, Leonid

    2014-10-10

    In the multicore era it was possible to exploit the increase in on-chip parallelism by simply running multiple MPI processes per chip. Unfortunately, manycore processors' greatly increased thread- and data-level parallelism coupled with a reduced memory capacity demand an altogether different approach. In this paper we explore augmenting two NWChem modules, triples correction of the CCSD(T) and Fock matrix construction, with OpenMP in order that they might run efficiently on future manycore architectures. As the next NERSC machine will be a self-hosted Intel MIC (Xeon Phi) based supercomputer, we leverage an existing MIC testbed at NERSC to evaluate our experiments. In order to proxy the fact that future MIC machines will not have a host processor, we run all of our experiments in tt native mode. We found that while straightforward application of OpenMP to the deep loop nests associated with the tensor contractions of CCSD(T) was sufficient in attaining high performance, significant effort was required to safely and efficiently thread the TEXAS integral package when constructing the Fock matrix. Ultimately, our new MPI OpenMP hybrid implementations attain up to 65x better performance for the triples part of the CCSD(T) due in large part to the fact that the limited on-card memory limits the existing MPI implementation to a single process per card. Additionally, we obtain up to 1.6x better performance on Fock matrix constructions when compared with the best MPI implementations running multiple processes per card.

  14. El cómic en la clase de ELE: una propuesta didáctica

    Directory of Open Access Journals (Sweden)

    Alonso Abal, Marina

    2012-06-01

    Full Text Available Suplemento del número 14 de marcoELE (enero - junio de 2012 La presente memoria pretende hacer una reflexión sobre el valor del cómic como herramienta pedagógica. Para ello y, como punto de partida, se plantean tres cuestiones que sirven como eje vertebrador de dicho trabajo. La primera tiene que ver con los motivos de su utilización en la clase de ELE. En dicho apartado, se tratan aspectos como el factor afectivo, lo lúdico, el humor, la interculturalidad, etc., todos ellos presentes en las tiras cómicas y que, tal y como se pone de manifiesto en el segundo bloque, en el que se analiza la finalidad de su explotación en el aula, favorecen un aprendizaje significativo en consonancia con los postulados del MCER y del PCIC. El tercer bloque pretende desarrollar de manera práctica los aspectos teóricos abordados anteriormente. Se presentan tres cómics que se utilizarán como eje central de tres secuencias de actividades, correspondientes a cada uno de los niveles del MCER (A, B, C. En cada secuencia se desarrollarán una serie de actividades para alcanzar un objetivo comunicativo concreto confirmando, así, el valor didáctico de los cómics más allá de la utilización de dicho material como actividad complementaria de revisión al final de la unidad, como una actividad aislada para practicar un determinado contenido lingüístico o como una mera distracción o una excusa para la conversación.

  15. Validitas Utrecht-Management Of Identity Commitments Scale (U-MICS) Versi Indonesia: Struktur Faktor, Invariansi Pengukuran Gender, dan Usia

    OpenAIRE

    Muttaqin, Darmawan

    2017-01-01

    The purpose of this study was to examine the psychometric properties of Indonesian version of the U-MICS, a measure three identity dimensions. Participants were 910 adolescents (12-21 years old). The Confirmatory Factor Analyses and Multi-Group Analyses were used to examine the factor structure, gender, and age measurement invariance of Indonesian version of the U-MICS. We further tested the gender and age differences using Multivariate Analysis of Variance. The results indicated that the fac...

  16. Initial steps in the microbially influenced corrosion (MIC) of metallic surfaces in a natural marine environment

    International Nuclear Information System (INIS)

    Esteso, M.A.; Estrella, C.N.; Dolores de la Rosa, M.; Martinez-Trujillo, R.; Rosales, B.M.; Podesta, J.J.

    1992-01-01

    Immersion of various metal samples in polluted seawater from Tenerife Harbor was followed by microbial attachment as an intermediate step in fouling development. The purpose of this research was to determine the initial steps in MIC by identifying the different microbial species attached to the respective metal or alloy. Image analysis was used to determine the morphologic changes in the metal surfaces. The corrosion products were determined by X-ray diffraction. The open circuit potentials were measured periodically and their variation with time used to assess the electrochemical behavior in the aforementioned marine environment

  17. Heavy Metals Pollution of Alluvial Soil in the Copşa Mică Area

    OpenAIRE

    , D. Popa; , I.M. Prundeanu; , R. Lăcătuşu

    2011-01-01

    The objective of our study was to determine the concentrations of heavy metals (Cd, Cr, Co, Cu, Mn, Ni, Pb, Zn and Fe) from soil samples, which have been previously treated with HNO3 and concentrated HClO4. The study was performed on a series of 24 soil samples and one soil profile, collected from the alluvial soil in the Copşa Mică area. The concentrations of heavy metals were determined using Atomic Absorption Spectrometry. The pH was determined by using the potentiometric method in aqueous...

  18. MIC damage in a water coolant header for remote process equipment

    International Nuclear Information System (INIS)

    Jenkins, C.F.

    1994-01-01

    Stainless steel water piping used to supply coolant for remote chemical separations equipment developed leaks during low flow conditions resulting from an extended interruption of operations. All the leaks occurred at welds in the bottom zone of the pipe, which was blanketed with silt deposits from the unfiltered well water used for cooling. Ultrasonic, radiographic, and metallographic examinations of leak sites revealed worm hole pitting adjacent to the welds. Seepage at the penetrations was strongly acidic and resulted in corrosion on the external pipe surfaces beneath brown crusty deposits which had developed. Analyses of the water and deposits suggest a strong propensity toward microbiologically influenced corrosion (MIC) and fouling

  19. Towards Porting a Real-World Seismological Application to the Intel MIC Architecture

    OpenAIRE

    V. Weinberg

    2014-01-01

    This whitepaper aims to discuss first experiences with porting an MPI-based real-world geophysical application to the new Intel Many Integrated Core (MIC) architecture. The selected code SeisSol is an application written in Fortran that can be used to simulate earthquake rupture and radiating seismic wave propagation in complex 3-D heterogeneous materials. The PRACE prototype cluster EURORA at CINECA, Italy, was accessed to analyse the MPI-performance of SeisSol on Intel Xeon Phi on both sing...

  20. El cómic en Ecuador, una historia en génesis permanente

    Directory of Open Access Journals (Sweden)

    José Daniel Santibáñez

    2012-09-01

    Full Text Available El presente artículo presenta una síntesis histórica del cómic en Ecuador y las diferentes tendencias temáticas y de uso, a través de su evolución, principalmente en los medios de información de masas. También se exponen los nombres de los cultores de este arte/medio y de los historietistas más reconocidos en el país.

  1. Application of Intel Many Integrated Core (MIC) accelerators to the Pleim-Xiu land surface scheme

    Science.gov (United States)

    Huang, Melin; Huang, Bormin; Huang, Allen H.

    2015-10-01

    The land-surface model (LSM) is one physics process in the weather research and forecast (WRF) model. The LSM includes atmospheric information from the surface layer scheme, radiative forcing from the radiation scheme, and precipitation forcing from the microphysics and convective schemes, together with internal information on the land's state variables and land-surface properties. The LSM is to provide heat and moisture fluxes over land points and sea-ice points. The Pleim-Xiu (PX) scheme is one LSM. The PX LSM features three pathways for moisture fluxes: evapotranspiration, soil evaporation, and evaporation from wet canopies. To accelerate the computation process of this scheme, we employ Intel Xeon Phi Many Integrated Core (MIC) Architecture as it is a multiprocessor computer structure with merits of efficient parallelization and vectorization essentials. Our results show that the MIC-based optimization of this scheme running on Xeon Phi coprocessor 7120P improves the performance by 2.3x and 11.7x as compared to the original code respectively running on one CPU socket (eight cores) and on one CPU core with Intel Xeon E5-2670.

  2. Optimizing the Betts-Miller-Janjic cumulus parameterization with Intel Many Integrated Core (MIC) architecture

    Science.gov (United States)

    Huang, Melin; Huang, Bormin; Huang, Allen H.-L.

    2015-10-01

    The schemes of cumulus parameterization are responsible for the sub-grid-scale effects of convective and/or shallow clouds, and intended to represent vertical fluxes due to unresolved updrafts and downdrafts and compensating motion outside the clouds. Some schemes additionally provide cloud and precipitation field tendencies in the convective column, and momentum tendencies due to convective transport of momentum. The schemes all provide the convective component of surface rainfall. Betts-Miller-Janjic (BMJ) is one scheme to fulfill such purposes in the weather research and forecast (WRF) model. National Centers for Environmental Prediction (NCEP) has tried to optimize the BMJ scheme for operational application. As there are no interactions among horizontal grid points, this scheme is very suitable for parallel computation. With the advantage of Intel Xeon Phi Many Integrated Core (MIC) architecture, efficient parallelization and vectorization essentials, it allows us to optimize the BMJ scheme. If compared to the original code respectively running on one CPU socket (eight cores) and on one CPU core with Intel Xeon E5-2670, the MIC-based optimization of this scheme running on Xeon Phi coprocessor 7120P improves the performance by 2.4x and 17.0x, respectively.

  3. Optimizing zonal advection of the Advanced Research WRF (ARW) dynamics for Intel MIC

    Science.gov (United States)

    Mielikainen, Jarno; Huang, Bormin; Huang, Allen H.

    2014-10-01

    The Weather Research and Forecast (WRF) model is the most widely used community weather forecast and research model in the world. There are two distinct varieties of WRF. The Advanced Research WRF (ARW) is an experimental, advanced research version featuring very high resolution. The WRF Nonhydrostatic Mesoscale Model (WRF-NMM) has been designed for forecasting operations. WRF consists of dynamics code and several physics modules. The WRF-ARW core is based on an Eulerian solver for the fully compressible nonhydrostatic equations. In the paper, we will use Intel Intel Many Integrated Core (MIC) architecture to substantially increase the performance of a zonal advection subroutine for optimization. It is of the most time consuming routines in the ARW dynamics core. Advection advances the explicit perturbation horizontal momentum equations by adding in the large-timestep tendency along with the small timestep pressure gradient tendency. We will describe the challenges we met during the development of a high-speed dynamics code subroutine for MIC architecture. Furthermore, lessons learned from the code optimization process will be discussed. The results show that the optimizations improved performance of the original code on Xeon Phi 5110P by a factor of 2.4x.

  4. Efficient Execution of Microscopy Image Analysis on CPU, GPU, and MIC Equipped Cluster Systems.

    Science.gov (United States)

    Andrade, G; Ferreira, R; Teodoro, George; Rocha, Leonardo; Saltz, Joel H; Kurc, Tahsin

    2014-10-01

    High performance computing is experiencing a major paradigm shift with the introduction of accelerators, such as graphics processing units (GPUs) and Intel Xeon Phi (MIC). These processors have made available a tremendous computing power at low cost, and are transforming machines into hybrid systems equipped with CPUs and accelerators. Although these systems can deliver a very high peak performance, making full use of its resources in real-world applications is a complex problem. Most current applications deployed to these machines are still being executed in a single processor, leaving other devices underutilized. In this paper we explore a scenario in which applications are composed of hierarchical data flow tasks which are allocated to nodes of a distributed memory machine in coarse-grain, but each of them may be composed of several finer-grain tasks which can be allocated to different devices within the node. We propose and implement novel performance aware scheduling techniques that can be used to allocate tasks to devices. We evaluate our techniques using a pathology image analysis application used to investigate brain cancer morphology, and our experimental evaluation shows that the proposed scheduling strategies significantly outperforms other efficient scheduling techniques, such as Heterogeneous Earliest Finish Time - HEFT, in cooperative executions using CPUs, GPUs, and MICs. We also experimentally show that our strategies are less sensitive to inaccuracy in the scheduling input data and that the performance gains are maintained as the application scales.

  5. Implementation of body area networks based on MICS/WMTS medical bands for healthcare systems.

    Science.gov (United States)

    Yuce, Mehmet R; Ho, Chee Keong

    2008-01-01

    A multi-hoping sensor network system has been implemented to monitor physiological parameters from multiple patient bodies by means of medical communication standards MICS (Medical Implant Communication Service) and WMTS (Wireless Medical Telemetry Service). Unlike the other medical sensor networks (they usually use 2.4 GHz ISM band), we used the two medical standards occupying the frequency bands that are mainly assigned to medical applications. The prototype system uses the MICS band (402-405 MHz) between the sensor nodes and a remote central control unit (CCU). And WMTS frequencies (608-614MHz) are used between the CCUs and the remote base stations allowing for a much larger range acting as an intermediate node. The sensor nodes in the prototype can measure up to four body signals (i.e. 4-channel) where one is dedicated to a continuous physiological signal such as ECC/EEG. The system includes firmware and software designs that can provide a long distance data transfer through the internet or a mobile network.

  6. MicROS-drt: supporting real-time and scalable data distribution in distributed robotic systems.

    Science.gov (United States)

    Ding, Bo; Wang, Huaimin; Fan, Zedong; Zhang, Pengfei; Liu, Hui

    A primary requirement in distributed robotic software systems is the dissemination of data to all interested collaborative entities in a timely and scalable manner. However, providing such a service in a highly dynamic and resource-limited robotic environment is a challenging task, and existing robot software infrastructure has limitations in this aspect. This paper presents a novel robot software infrastructure, micROS-drt, which supports real-time and scalable data distribution. The solution is based on a loosely coupled data publish-subscribe model with the ability to support various time-related constraints. And to realize this model, a mature data distribution standard, the data distribution service for real-time systems (DDS), is adopted as the foundation of the transport layer of this software infrastructure. By elaborately adapting and encapsulating the capability of the underlying DDS middleware, micROS-drt can meet the requirement of real-time and scalable data distribution in distributed robotic systems. Evaluation results in terms of scalability, latency jitter and transport priority as well as the experiment on real robots validate the effectiveness of this work.

  7. Epidemiological cut-off values for Flavobacterium psychrophilum MIC data generated by a standard test protocol.

    Science.gov (United States)

    Smith, P; Endris, R; Kronvall, G; Thomas, V; Verner-Jeffreys, D; Wilhelm, C; Dalsgaard, I

    2016-02-01

    Epidemiological cut-off values were developed for application to antibiotic susceptibility data for Flavobacterium psychrophilum generated by standard CLSI test protocols. The MIC values for ten antibiotic agents against Flavobacterium psychrophilum were determined in two laboratories. For five antibiotics, the data sets were of sufficient quality and quantity to allow the setting of valid epidemiological cut-off values. For these agents, the cut-off values, calculated by the application of the statistically based normalized resistance interpretation method, were ≤16 mg L(-1) for erythromycin, ≤2 mg L(-1) for florfenicol, ≤0.025 mg L(-1) for oxolinic acid (OXO), ≤0.125 mg L(-1) for oxytetracycline and ≤20 (1/19) mg L(-1) for trimethoprim/sulphamethoxazole. For ampicillin and amoxicillin, the majority of putative wild-type observations were 'off scale', and therefore, statistically valid cut-off values could not be calculated. For ormetoprim/sulphadimethoxine, the data were excessively diverse and a valid cut-off could not be determined. For flumequine, the putative wild-type data were extremely skewed, and for enrofloxacin, there was inadequate separation in the MIC values for putative wild-type and non-wild-type strains. It is argued that the adoption of OXO as a class representative for the quinolone group would be a valid method of determining susceptibilities to these agents. © 2014 John Wiley & Sons Ltd.

  8. Management and control of microbiologically influenced corrosion (MIC) in the oil and gas industry - Overview and a North Sea case study

    DEFF Research Database (Denmark)

    Skovhus, Torben Lund; Eckert, Richard B; Rodrigues, Edgar

    2017-01-01

    the oil and gas industry has seen regarding MIC research over the past decade. The paper starts out with an overview of where in the process stream MIC occurs - from the oil reservoir to the consumer. Both biotic and abiotic corrosion mechanisms are explained in the context of managing MIC using...... to manage the corrosion threat, operators commonly use models to support decision making. The models use qualitative, semi-quantitative or quantitative measures to help assess the rate of degradation caused by MIC. The paper reviews four existing models for MIC Threat Assessment and describe a new model...

  9. On the mechanism of rapid postirradiation recovery of yeast

    International Nuclear Information System (INIS)

    Glazunov, A.V.; Kapul'tsevich, Yu.G.

    1983-01-01

    Rapid postirradiation recovery of diploid yeast Saccharomyces cerevisiae is equally effective both in water and in a liquid nutrition medium. In the haploid strains, rapid recovery occurs more readily in the log phase than in the stationary phase of growth. In the diploid strains, rapid recovery is more effective in the log phase than in the stationary phase. Rapid recovery of yeast does not require an additional protein synthesis. Damages induced by UV-light are not sub ected to rapid recovery

  10. Herramienta observacional para el estudio de conductas violentas en un cómic audiovisual

    Directory of Open Access Journals (Sweden)

    Zaida Márquez

    2012-01-01

    Full Text Available Abstract This research paper presents a study which aimed to structure a system of categories for observation and description of violent behavior within an audiovisual children program, specifically in cartoons. A chapter of an audiovisual cartoon was chosen as an example. This chapter presented three main female characters in a random fashion in order to be observed by the children. Categories were established using the taxonomic criteria proposed by Anguera (2001 and were made up of various typed behaviors according to levels of response. To identify a stable behavioral pattern, some events were taken as a sample, taking into account one or several behavior registered in the observed sessions. The episode was analyzed by two observers who appreciated the material simultaneously, making two observations, registering the relevant data and contrasting opinions. The researchers determined a set of categories which expressed violent behavior such as: Nonverbal behavior, special behavior, and vocal/verbal behavior. It was concluded that there was a pattern of predominant and stable violent behavior in the cartoon observed. Resumen El presente artículo de investigación presenta un trabajo cuyo objetivo consistió en estructurar un sistema de categorías para la observación y descripción de conductas violentas en un cómic audiovisual (dibujo animado. Se seleccionó como muestra un cómic audiovisual que tiene tres personajes principales femeninos; tomándose de forma aleatoria, para su observación, uno de sus capítulos. Para el establecimiento de las categorías se escogieron como base los criterios taxonómicos propuestos por Anguera (2001, con lo cual se tipificaron las conductas que conforman cada categoría según los niveles de respuesta. Y para identificar un patrón de conducta estable se ha realizado un muestreo de eventos, usando todas las ocurrencias de una o varias conductas que se registraron en las sesiones observadas. El episodio

  11. High MICs for Vancomycin and Daptomycin and Complicated Catheter-Related Bloodstream Infections with Methicillin-Sensitive Staphylococcus aureus

    Science.gov (United States)

    Viedma, Esther; Chaves, Fernando; Lalueza, Antonio; Fortún, Jesús; Loza, Elena; Pujol, Miquel; Ardanuy, Carmen; Morales, Isabel; de Cueto, Marina; Resino-Foz, Elena; Morales-Cartagena, Alejandra; Rico, Alicia; Romero, María P.; Orellana, María Ángeles; López-Medrano, Francisco; Fernández-Ruiz, Mario; Aguado, José María

    2016-01-01

    We investigated the prognostic role of high MICs for antistaphylococcal agents in patients with methicillin-sensitive Staphylococcus aureus catheter-related bloodstream infection (MSSA CRBSI). We prospectively reviewed 83 episodes from 5 centers in Spain during April 2011–June 2014 that had optimized clinical management and analyzed the relationship between E-test MICs for vancomycin, daptomycin, oxacillin, and linezolid and development of complicated bacteremia by using multivariate analysis. Complicated MSSA CRBSI occurred in 26 (31.3%) patients; MICs for vancomycin and daptomycin were higher in these patients (optimal cutoff values for predictive accuracy = 1.5 μg/mL and 0.5 μg/mL). High MICs for vancomycin (hazard ratio 2.4, 95% CI 1.2–5.5) and daptomycin (hazard ratio 2.4, 95% CI 1.1–5.9) were independent risk factors for development of complicated MSSA CRBSI. Our data suggest that patients with MSSA CRBSI caused by strains that have high MICs for vancomycin or daptomycin are at increased risk for complications. PMID:27192097

  12. THE CHIRONOMIDAE ASSEMBLAGES IN SOMESUL MIC RIVER (ROMANIA DURING 1996 AND 1997

    Directory of Open Access Journals (Sweden)

    Maria-Monica Tudorancea

    2001-01-01

    Full Text Available The communities of Chironomidae larvae in the Gilau – Gherla sector of the Somesul Mic River (Transylvania, Romania were studied during 1996 and 1997 in order to compare their species composition and to see if their component species could be good indicators for water quality deterioration. A total of 102 species were recorded, out of which 12 are new records for the Romanian fauna. Four of these species are known only from East Asia and from the North America. Some species such as Chironomus thumi, Microcricotopus bicolor, Dicrotendipes nervosus and Dicrotendipes notatus occurred in organically enriched waters. Other species, such as Cricotopus algarum, Cricotopus bicinctus, Cricotopus tremulus and Cricotopus trifasciatus occurred in both clean and organically polluted water which indicate they are not good bioindicators for water quality deterioration.

  13. The Poincaré compactification of the MIC-Kepler problem with positive energies

    CERN Document Server

    Iwai, T

    2001-01-01

    The Poincare compactification and the symplectic reduction methods are first reviewed and then used to study the behaviour at infinity of the MIC (McIntosh-Cisneros)-Kepler problem at positive energies. The hyperbolic orbits leave the unstable equilibrium point set at infinity and tend eventually to the stable equilibrium point set at infinity. Both of these equilibrium point sets are diffeomorphic with S/sup 2/, the unit sphere in R/sup 3/. The hyperbolic orbits determine a map of the unstable equilibrium point set to the stable equilibrium point set in such a manner that the initial point (or the limit point as t to - infinity ) of an orbit is mapped to its final point (or the limit point as t to infinity ). This map is found explicitly as a rotation matrix which depends on the energy and the angular momentum of the orbits. (9 refs).

  14. Influence of subinhibitory-concentration (sub-MIC Cefetoxime on biofilm formation. SEM study of ESBL-producing Salmonella typhi

    Directory of Open Access Journals (Sweden)

    Rahul Narasanna, Manjunath Chavadi, Ajaykumar Oli

    2017-06-01

    Full Text Available Objectives: In the present study, we have analyzed ESBL-producing S. typhi’s capability in forming a significant amount of biofilm on plastic and glass surface, and the influence of cefetoxime on biofilm development at subinhibitory (Sub-MIC concentration. Methods: Nine strains of cefetoxime-mediated ESBL-producing S. typhi were used in the study. S. typhi formed biofilm on plastic and glass materials; it was demonstrated using micro titre plate (MTP and standard test tube methods. Comparative study of the influence of cefetoxime on biofilm formation in its MIC (128 µg/ml and at sub-MIC (64 µg/ml was demonstrated by microtitre plate method. The biofilm production was observed in SEM images, statistical analysis (ANOVA showed significant increase in cell surface and volume due to the influence of Cefetoxime. Results: Of the nine selected isolates, two S. typhi strains, namely BST 51 and BST 130, produced relatively strong biofilm in the presence of cefetoxime at sub-MIC level (64 µg/ml, comparatively weak biofilm formation at MIC level (128 µg/ml. Typical morphological changes were observed in cefetoxime-resistant strains, S. typhi BST 51 and BST 130, in comparison to cefetoxime-sensitive strain S. typhi BST 63 used as a control. We found an increase in surface and volume of a cell in response to cefetoxime and statistical data (ANOVA proved that resistant strains were significantly different from control strains. Conclusion: The above study clearly shows that cefetoxime at sub-MIC level efficiently induces biofilm formation and promotes changes in morphology of the cell. J Microbiol Infect Dis 2017; 7(2: 67-75

  15. Recovery Spirituality

    Directory of Open Access Journals (Sweden)

    Ernest Kurtz

    2015-01-01

    Full Text Available There is growing interest in Alcoholics Anonymous (A.A. and other secular, spiritual, and religious frameworks of long-term addiction recovery. The present paper explores the varieties of spiritual experience within A.A., with particular reference to the growth of a wing of recovery spirituality promoted within A.A. It is suggested that the essence of secular spirituality is reflected in the experience of beyond (horizontal and vertical transcendence and between (connection and mutuality and in six facets of spirituality (Release, Gratitude, Humility, Tolerance, Forgiveness, and a Sense of Being-at-home shared across religious, spiritual, and secular pathways of addiction recovery. The growing varieties of A.A. spirituality (spanning the “Christianizers” and “Seculizers” reflect A.A.’s adaptation to the larger diversification of religious experience and the growing secularization of spirituality across the cultural contexts within which A.A. is nested.

  16. The Relationship Between Vancomycin Trough Concentrations and AUC/MIC Ratios in Pediatric Patients: A Qualitative Systematic Review.

    Science.gov (United States)

    Tkachuk, Stacey; Collins, Kyle; Ensom, Mary H H

    2018-04-01

    In adults, the area under the concentration-time curve (AUC) divided by the minimum inhibitory concentration (MIC) is associated with better clinical and bacteriological response to vancomycin in patients with methicillin-resistant Staphylococcus aureus who achieve target AUC/MIC ≥ 400. This target is often extrapolated to pediatric patients despite the lack of similar evidence. The impracticalities of calculating the AUC in practice means vancomycin trough concentrations are used to predict the AUC/MIC. This review aimed to determine the relationship between vancomycin trough concentrations and AUC/MIC in pediatric patients. We searched the MEDLINE and Embase databases, the Cochrane Database of Systematic Reviews, and the Cochrane Central Register of Controlled Trials using the medical subject heading (MeSH) terms vancomycin and AUC and pediatric* or paediatric*. Articles were included if they were published in English and reported a relationship between vancomycin trough concentrations and AUC/MIC. Of 122 articles retrieved, 11 met the inclusion criteria. One trial reported a relationship between vancomycin trough concentrations, AUC/MIC, and clinical outcomes but was likely underpowered. Five studies found troughs 6-10 mg/l were sufficient to attain an AUC/MIC > 400 in most general hospitalized pediatric patients. One study in patients undergoing cardiothoracic surgery found a trough of 18.4 mg/l achieved an AUC/MIC > 400. Two oncology studies reported troughs ≥ 15 mg/l likely attained an AUC/MIC ≥ 400. In critical care patients: one study found a trough of 9 mg/l did not attain the AUC/MIC target; another found 7 mg/l corresponded to an AUC/MIC of 400. Potential vancomycin targets varied based on the population studied but, for general hospitalized pediatric patients, troughs of 6-10 mg/l are likely sufficient to achieve AUC/MIC ≥ 400. For MIC ≥ 2 mg/l, higher troughs are likely necessary to achieve an AUC/MIC ≥ 400. More

  17. Vehicle recovery and towing guideline

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-01-15

    This guideline was developed to provide light and medium duty vehicles operators in the oil and gas industry with a set of best practices for avoiding injury and damage during the recovery of stuck vehicles. The aim of the guideline was to increase awareness of safety issues and promote the safe usage of the vehicles by personnel throughout the petroleum industry and to establish minimum standards of practice for vehicle recovery. The guideline included a step-by-step guide for pulling out a vehicle with a recovery strap as well as vehicle-mounted winch procedures. Pre-job checklists for both procedures were provided. Issues related to the strength rating of vehicle tow hooks and hitch receivers were discussed, as well as some of the hazards associated with steep terrains and heavy mud. The guideline also included recommendations for a vehicle recovery kit with instructions on vehicle recovery, a recovery strap, a recovery hitch and shackle, a collapsible shovel, traffic cones and reflector flares, and a heavy blanket and gloves. 7 refs., 2 tabs., 13 figs.

  18. Minimal inhibitory concentration (MIC determination of disinfectant and/or sterilizing agents

    Directory of Open Access Journals (Sweden)

    Priscila Gava Mazzola

    2009-06-01

    Full Text Available Due to the growing number of outbreaks of infection in hospital and nurseries, it becomes essential to set up a sanitation program that indicates that the appropriate chemical agent was chosen for application in the most effective way. Validating the effectiveness of decontamination and disinfection is an important and often challenging task. In order to study and compare the behavior of selected microorganisms, they were submitted to minimal inhibitory concentration (MIC. The MIC intervals, which reduced bacteria populations over 6 log10, were: 59 to 156 mg/L of quaternary ammonium compounds (QACs; 63 to 10000 mg/L of chlorhexidine; 1375 to 3250 mg/L of glutaraldehyde; 39 to 246 mg/L of formaldehyde; 43750 to 87500 mg/L of ethanol; 1250 to 6250 mg/L of iodine in polyvinyl-pyrolidone complexes, 150 to 4491 mg/L of chlorine-releasing-agents (CRAs and 469 to 2500 mg/L of hydrogen peroxide. Chlorhexidine showed non inhibitory activity over germinating spores. A. calcoaceticus showed resistance to the majority of the agents tested, followed by E. cloacae and S. marcescens.Devido ao número crescente de surtos de infecção hospitalar, torna-se proeminente o estabelecimento de um programa de sanitização que liste os agentes químicos a serem empregados e o modo de aplicação mais efetivo. Validação da eficácia de descontaminação é uma tarefa ao mesmo tempo importante e desafiadora. Para estudar e comparar o comportamento dos microrganismos selecionados foram realizados ensaios de concentração inibitória mínima (CIM. A CIM capaz de reduzir o bioburden inicial (>6 log10 foi: 59 - 156 mg/L de quartenários de amônia; 63 - 10000 mg/L de clorexidina, 1375 - 3250 mg/mL de glutaraldeído, 39 - 246 mg/L de formaldeído, 43750 - 87500 mg/L de etanol 1250 - 6250 mg/L de PVPI, 150 - 4491 mg/L de compostos liberadores de cloro e 469 -2500 mg/L de peróxido de hidrogênio.

  19. [Severe diarrhea after the original well-functioning percutaneous endoscopic gastrostomy tube was replaced by a Mic-Key button].

    Science.gov (United States)

    Jensen, Susanne Wigh; Eriksen, Jan; Kristensen, Kurt

    2006-03-06

    We report two cases of colocutaneous fistula as a complication of percutaneous endoscopic gastrostomy (PEG) in small children. Both children developed severe osmotic diarrhoea immediately after the original PEG tube was replaced by a Mic-Key button which subsequently migrated to the colon.

  20. Overexpression of MicA induces production of OmpC-enriched outer membrane vesicles that protect against Salmonella challenge.

    Science.gov (United States)

    Choi, Hyun-Il; Kim, Moonjeong; Jeon, Jinseong; Han, Jin Kwan; Kim, Kwang-Sun

    2017-08-26

    Outer membrane vesicles (OMVs) derived from bacteria are promising candidates for subunit vaccines. Stresses that modulate the composition of outer membrane proteins (OMPs) are important for OMV synthesis. Small RNAs (sRNAs) expressed in response to stress regulate OMPs, although the mechanism underlying sRNA-mediated OMV biogenesis and its utility for developing vaccine platforms remains to be elucidated. Here, we characterized the role of a sRNA, MicA, which regulates OmpA, a major OMP involved in both production of OMVs and reactive immunity against Salmonella challenge. A Salmonella strain overexpressing MicA generated more OMVs than a control strain. In addition, OmpC was the major component of MicA-derived OMV proteins. MicA-derived OMVs induced Th1- and Th17-type immune responses in vitro and reduced Salmonella-mediated lethality in a mouse model. Thus, OmpA-regulatory sRNA-derived OMVs may facilitate production of Salmonella-protective vaccines. Copyright © 2017 Elsevier Inc. All rights reserved.

  1. Relationship between the clinical efficacy and AUC/MIC of intravenous ciprofloxacin in Japanese patients with intraabdominal infections.

    Science.gov (United States)

    Ohki, Emiko; Yamagishi, Yuka; Mikamo, Hiroshige

    2013-10-01

    The efficacy of fluoroquinolones (FQs) correlates with the pharmacokinetic/pharmacodynamic (PK-PD) parameter, AUC/MIC. To our knowledge, however, no prospective studies have reported the relationship between FQ efficacy and PK-PD parameters in intraabdominal infection; therefore, we prospectively investigated the relationship between the efficacy of intravenous ciprofloxacin (CPFX IV) and PK-PD parameters. The study included 16 patients diagnosed with peritonitis between 2006 and 2008: 14 patients infected with a single organism and 2 patients infected with more than one organism. Each patient was treated with CPFX IV (300 mg twice daily). The response rate was 56% (9 responders and 7 non-responders). Non-responders were infected with Escherichia coli, Pseudomonas aeruginosa, and Bacteroides fragilis (6 patients were infected with a single organism and 1 with more than one organism). Plasma drug concentrations were measured 1 h and 2 or 4 h after administration of CPFX IV. AUC for 24 h (AUC(0-24))/MIC values was calculated. The range of AUC(0-24)/MIC values in responders [95.3-3628.4 (geometric mean, 521.6)] was significantly different from that in non-responders [7.0-45.2 (geometric mean, 16.5)] (p = 0.001). The target AUC/MIC value of CPFX IV would be considered to be 45-95 in patients with peritonitis.

  2. Un nuevo enfoque para la explotación del cómic en E/LE

    Directory of Open Access Journals (Sweden)

    Consuelo Escudero Medina

    2012-08-01

    Full Text Available En esta ocasión, nos hemos decantado por trabajar con el cómic.  Los elementos que configuran este material favorecen sobre todo la motivación del alumno, puesto que no le son ajenos, existen en su cultura.

  3. El aprovechamiento del cómic como herramienta didáctica desde el enfoque comunicativo

    Directory of Open Access Journals (Sweden)

    Isabel García Martínez

    2015-10-01

    Full Text Available El cómic es un recurso que, en muchos casos, se utiliza de modo anecdótico en el aula y con una función puramente de entretenimiento, sin dar muchas veces la importancia que se merece a lo que muchos consideran el noveno arte. Esta experiencia práctica pretende mostrar la idoneidad y la versatilidad de este medio narrativo en el aula de español como lengua extranjera. Tras un breve acercamiento teórico al uso del cómic en el aula de E/LE, se presentan los resultados de un análisis previo sobre la presencia de cómics en los manuales de E/LE. Las diferentes aplicaciones didácticas que se presentan, dirigidas a diferentes niveles que oscilan desde el nivel B1 hasta el C2, suplen las carencias detectadas en el mencionado análisis, utilizan cómics españoles e hispanoamericanos, y fomentan el uso de las TIC y los álbumes completos.

  4. Un nuevo enfoque para la explotación del cómic en E/LE

    Directory of Open Access Journals (Sweden)

    Consuelo Escudero Medina

    2007-01-01

    Full Text Available En esta ocasión, nos hemos decantado por trabajar con el cómic. Los elementos que configuran este material favorecen sobre todo la motivación del alumno, puesto que no le son ajenos, existen en su cultura.

  5. Ceftaroline efficacy against high-MIC clinical Staphylococcus aureus isolates in an in vitro hollow-fibre infection model.

    Science.gov (United States)

    Singh, Renu; Almutairi, Mashal; Alm, Richard A; Lahiri, Sushmita D; San Martin, Maryann; Chen, April; Ambler, Jane E

    2017-10-01

    The current CLSI and EUCAST clinical susceptible breakpoint for 600 mg q12h dosing of ceftaroline (active metabolite of ceftaroline fosamil) for Staphylococcus aureus is ≤1 mg/L. Efficacy data for S. aureus infections with ceftaroline MIC ≥2 mg/L are limited. This study was designed to generate in-depth pharmacokinetic/pharmacodynamics (PK/PD) understanding of S. aureus isolates inhibited by ≥ 2 mg/L ceftaroline using an in vitro hollow-fibre infection model (HFIM). The PK/PD target of ceftaroline was investigated against 12 diverse characterized clinical MRSA isolates with ceftaroline MICs of 2 or 4 mg/L using q8h dosing for 24 h. These isolates carried substitutions in the penicillin-binding domain (PBD) and/or the non-PBD. Additionally, PD responses of mutants with ceftaroline MICs ranging from 2 to 32 mg/L were evaluated against the mean 600 mg q8h human-simulated dose over 72 h. The mean stasis, 1 log10-kill and 2 log10-kill PK/PD targets were 29%, 32% and 35% f T>MIC, respectively. In addition, these data suggest that the PK/PD target for MRSA is not impacted by the presence of substitutions in the non-PBD commonly found in isolates with ceftaroline MIC values of ≤ 2 mg/L. HFIM studies with 600 mg q8h dosing demonstrated a sustained long-term bacterial suppression for isolates with ceftaroline MICs of 2 and 4 mg/L. Overall, efficacy was demonstrated against a diverse collection of clinical isolates using HFIM indicating the utility of 600 mg ceftaroline fosamil for S. aureus isolates with MIC ≤4 mg/L using q8h dosing. © The Author 2017. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  6. UNC-Utah NA-MIC Framework for DTI Fiber Tract Analysis

    Directory of Open Access Journals (Sweden)

    Audrey Rose Verde

    2014-01-01

    Full Text Available Diffusion tensor imaging has become an important modality in the field ofneuroimaging to capture changes in micro-organization and to assess white matterintegrity or development. While there exists a number of tractography toolsets,these usually lack tools for preprocessing or to analyze diffusion properties alongthe fiber tracts. Currently, the field is in critical need of a coherent end-to-endtoolset for performing an along-fiber tract analysis, accessible to non-technicalneuroimaging researchers. The UNC-Utah NA-MIC DTI framework represents acoherent, open source, end-to-end toolset for atlas fiber tract based DTI analysisencompassing DICOM data conversion, quality control, atlas building, fibertractography, fiber parameterization, and statistical analysis of diffusionproperties. Most steps utilize graphical user interfaces (GUI to simplifyinteraction and provide an extensive DTI analysis framework for non-technicalresearchers/investigators. We illustrate the use of our framework on a smallsample, cross sectional neuroimaging study of 8 healthy 1-year-old children fromthe Infant Brain Imaging Study (IBIS Network. In this limited test study, weillustrate the power of our method by quantifying the diffusion properties at 1year of age on the genu and splenium fiber tracts.

  7. UNC-Utah NA-MIC framework for DTI fiber tract analysis.

    Science.gov (United States)

    Verde, Audrey R; Budin, Francois; Berger, Jean-Baptiste; Gupta, Aditya; Farzinfar, Mahshid; Kaiser, Adrien; Ahn, Mihye; Johnson, Hans; Matsui, Joy; Hazlett, Heather C; Sharma, Anuja; Goodlett, Casey; Shi, Yundi; Gouttard, Sylvain; Vachet, Clement; Piven, Joseph; Zhu, Hongtu; Gerig, Guido; Styner, Martin

    2014-01-01

    Diffusion tensor imaging has become an important modality in the field of neuroimaging to capture changes in micro-organization and to assess white matter integrity or development. While there exists a number of tractography toolsets, these usually lack tools for preprocessing or to analyze diffusion properties along the fiber tracts. Currently, the field is in critical need of a coherent end-to-end toolset for performing an along-fiber tract analysis, accessible to non-technical neuroimaging researchers. The UNC-Utah NA-MIC DTI framework represents a coherent, open source, end-to-end toolset for atlas fiber tract based DTI analysis encompassing DICOM data conversion, quality control, atlas building, fiber tractography, fiber parameterization, and statistical analysis of diffusion properties. Most steps utilize graphical user interfaces (GUI) to simplify interaction and provide an extensive DTI analysis framework for non-technical researchers/investigators. We illustrate the use of our framework on a small sample, cross sectional neuroimaging study of eight healthy 1-year-old children from the Infant Brain Imaging Study (IBIS) Network. In this limited test study, we illustrate the power of our method by quantifying the diffusion properties at 1 year of age on the genu and splenium fiber tracts.

  8. Extension of the AMBER molecular dynamics software to Intel's Many Integrated Core (MIC) architecture

    Science.gov (United States)

    Needham, Perri J.; Bhuiyan, Ashraf; Walker, Ross C.

    2016-04-01

    We present an implementation of explicit solvent particle mesh Ewald (PME) classical molecular dynamics (MD) within the PMEMD molecular dynamics engine, that forms part of the AMBER v14 MD software package, that makes use of Intel Xeon Phi coprocessors by offloading portions of the PME direct summation and neighbor list build to the coprocessor. We refer to this implementation as pmemd MIC offload and in this paper present the technical details of the algorithm, including basic models for MPI and OpenMP configuration, and analyze the resultant performance. The algorithm provides the best performance improvement for large systems (>400,000 atoms), achieving a ∼35% performance improvement for satellite tobacco mosaic virus (1,067,095 atoms) when 2 Intel E5-2697 v2 processors (2 ×12 cores, 30M cache, 2.7 GHz) are coupled to an Intel Xeon Phi coprocessor (Model 7120P-1.238/1.333 GHz, 61 cores). The implementation utilizes a two-fold decomposition strategy: spatial decomposition using an MPI library and thread-based decomposition using OpenMP. We also present compiler optimization settings that improve the performance on Intel Xeon processors, while retaining simulation accuracy.

  9. Implementation of an Agent-Based Parallel Tissue Modelling Framework for the Intel MIC Architecture

    Directory of Open Access Journals (Sweden)

    Maciej Cytowski

    2017-01-01

    Full Text Available Timothy is a novel large scale modelling framework that allows simulating of biological processes involving different cellular colonies growing and interacting with variable environment. Timothy was designed for execution on massively parallel High Performance Computing (HPC systems. The high parallel scalability of the implementation allows for simulations of up to 109 individual cells (i.e., simulations at tissue spatial scales of up to 1 cm3 in size. With the recent advancements of the Timothy model, it has become critical to ensure appropriate performance level on emerging HPC architectures. For instance, the introduction of blood vessels supplying nutrients to the tissue is a very important step towards realistic simulations of complex biological processes, but it greatly increased the computational complexity of the model. In this paper, we describe the process of modernization of the application in order to achieve high computational performance on HPC hybrid systems based on modern Intel® MIC architecture. Experimental results on the Intel Xeon Phi™ coprocessor x100 and the Intel Xeon Phi processor x200 are presented.

  10. Chelsea Boys: paradigmas sexuales de un cómic queer

    Directory of Open Access Journals (Sweden)

    Rafael Manuel Mérida Jiménez

    2009-01-01

    Full Text Available Más allá del barrio neoyorquino que da título a este serie de volúmenes –aunque en diálogo tanto con su realidad como con sus representaciones anteriores, como Rear Window, dónde se presenta ya como espacio sexualizado–; y más allá del estereotipo gay que la misma expresión representa, Chelsea Boys aparece como un espacio de ruptura de clichés. En el contexto del cómic gay norteamericano que se repasa en este artículo, constituye una propuesta plural, donde la universalidad de las situaciones que representa superan tanto el localismo como la rigidez estereotípica de algunas creaciones anteriores. En él emerge una comunidad queer a través de cuya representación se plantean cuestiones cruciales en y para la/s realidad/es gays.

  11. [Efficacy of a multidisciplinary care management program for patients admitted at hospital because of heart failure (ProMIC)].

    Science.gov (United States)

    Domingo, Cristina; Aros, Fernando; Otxandategi, Agurtzane; Beistegui, Idoia; Besga, Ariadna; Latorre, Pedro María

    2018-02-26

    To assess the efficacy of the ProMIC, multidisciplinary program for patients admitted at hospital because of heart failure (HF) programme, in reducing the HF-related readmission rate. Quasi-experimental research with control group. Twelve primary health care centres and 3 hospitals from the Basque Country. Aged 40 years old or above patients admitted for HF with a New York Heart Association functional class II to IV. Patients in the intervention group carried out the ProMIC programme, a structured clinical intervention based on clinical guidelines and on the chronic care model. Control group received usual care. The rate of readmission for HF and health-related quality of life RESULTS: One hundred fifty five patients were included in ProMIC group and 129 in control group. 45 rehospitalisation due to heart failure happened in ProMIC versus 75 in control group (adjusted hazard ratio=0.59, CI 95%: 0.36-0.98; P=.049). There were significant differences in specific quality of life al 6 months. No significant differences were found in rehospitalisation due to all causes, due to cardiovascular causes, visits to emergency room, mortality, the combined variable of these events, the functional capacity or quality of life at 12 months of follow up. ProMIC reduces significantly heart failure rehospitalisation and improve quality of life al 6 months of follow up. No significant differences were found in the rests of variables. Copyright © 2018 The Authors. Publicado por Elsevier España, S.L.U. All rights reserved.

  12. The ciprofloxacin target AUC : MIC ratio is not reached in hospitalized patients with the recommended dosing regimens.

    Science.gov (United States)

    Haeseker, Michiel; Stolk, Leo; Nieman, Fred; Hoebe, Christian; Neef, Cees; Bruggeman, Cathrien; Verbon, Annelies

    2013-01-01

    The aim of this study was to determine the ciprofloxacin serum concentrations in hospitalized patients and to determine which percentage reached the efficacy target of AUC : MIC > 125. Additionally, the influence of demographic anthropomorphic and clinical parameters on the pharmacokinetics and pharmacodynamics of ciprofloxacin were investigated. In serum of 80 hospitalized patients ciprofloxacin concentrations were measured with reverse phase high performance liquid chromatography with fluorescence detection. The ciprofloxacin dose was 400-1200 mg day(-1) i.v. in two or three doses depending on renal function and causative bacteria. Pharmacokinetic parameters were calculated with maximum a posteriori Bayesian estimation (MW\\PHARM 3.60). A two compartment open model was used. Mean (± SD) age was 66 (± 17) years, the mean clearance corrected for bodyweight was 0.24 l h(-1) kg(-1) and the mean AUC was 49 mg l(-1) h. Ciprofloxacin clearance and thus AUC were associated with both age and serum creatinine. Of all patients, 21% and 75% of the patients, did not reach the proposed ciprofloxacin AUC : MIC > 125 target with MICs of 0.25 and 0.5 mg l(-1), respectively. A computer simulated increase in the daily dose from 800 mg to 1200 mg, decreased these percentages to 1% and 37%, respectively. A substantial proportion of the hospitalized patients did not reach the target ciprofloxacin AUC : MIC and are suboptimally dosed with recommended doses. Taking into account the increasing resistance to ciprofloxacin worldwide, a ciprofloxacin dose of 1200 mg i.v. daily in patients with normal renal function is necessary to reach the targeted AUC : MIC > 125. © 2012 The Authors. British Journal of Clinical Pharmacology © 2012 The British Pharmacological Society.

  13. Damage Recovery in Carrara Marble

    Science.gov (United States)

    Meyer, G.; Brantut, N.; Mitchell, T. M.; Meredith, P. G.

    2017-12-01

    We investigate the effect of confining pressure on the recovery of elastic wave velocities following deformation episodes in Carrara Marble. Dry Carrara Marble cores were deformed in the ductile regime (Pc = 40 MPa) up to 3% axial strain. After deformation, samples were held at constant stress conditions for extended periods of time (5-8 days) whilst continuously recording volumetric strain and seismic wave velocities. The velocity data were used to invert for microcrack densities using an effective medium approach. Finally, thin sections were produced to characterise the microstructures after recovery. During deformation, elastic wave speeds decreased with increasing strain by more than 30% of the value for the intact rock due to the formation of distributed microcracks. Under constant hydrostatic pressure, wave speeds progressively recovered 12-90% of the initial drop, depending on the applied confining pressure. In contrast, the strain recovery (deformation towards the initial shape of the sample) during holding time is negligible (of the order of 10-4). Tests performed under nonhydrostatic (triaxial) stress conditions during recovery showed some time-dependent creep deformation together with very significant recovery of wave velocities. The recovery is interpreted as a progressive reduction in crack density within the sample. The process is highly dependent on confining pressure, which favours it. We propose that the driving process for wave speed recovery is the time-dependent increase of contact area between crack surfaces due to the formation and growth of asperity contacts. We develop a micromechanical model for crack closure driven by asperity creep, which shows a good fit to the experimental data. Most of the recovery is achieved in the initial few hours, implying it is the fastest recovery or healing process, and thus occurs prior to any chemical healing or mineral precipitation. Our data corroborate field observations of post-seismic fault behavior.

  14. Selective medium for culture of Mycoplasma hyopneumoniae.

    Science.gov (United States)

    Cook, Beth S; Beddow, Jessica G; Manso-Silván, Lucía; Maglennon, Gareth A; Rycroft, Andrew N

    2016-11-15

    The fastidious porcine respiratory pathogen Mycoplasma hyopneumoniae has proven difficult to culture since it was first isolated in 1965. A reliable solid medium has been particularly challenging. Moreover, clinical and pathological samples often contain the fast-growing M. hyorhinis which contaminates and overgrows M. hyopneumoniae in primary culture. The aim of this study was to optimise the culture medium for recovery of M. hyopneumoniae and to devise a medium for selection of M. hyopneumoniae from clinical samples also containing M. hyorhinis. The solid medium devised by Niels Friis was improved by use of Purified agar and incorporation of DEAE-dextran. Addition of glucose or neutralization of acidity in liquid medium with NaOH did not improve the final yield of viable organisms or alter the timing of peak viability. Analysis of the relative susceptibility of M. hyopneumoniae and M. hyorhinis strains to four antimicrobials showed that M. hyopneumoniae is less susceptible than M. hyorhinis to kanamycin. This was consistent in all UK and Danish strains tested. A concentration of 2μg/ml of kanamycin selectively inhibited the growth of all M. hyorhinis tested, while M. hyopneumoniae was able to grow. This forms the basis of an effective selective culture medium for M. hyopneumoniae. Copyright © 2016 The Authors. Published by Elsevier B.V. All rights reserved.

  15. Serum levels of human MIC-1/GDF15 vary in a diurnal pattern, do not display a profile suggestive of a satiety factor and are related to BMI

    DEFF Research Database (Denmark)

    Tsai, Vicky Wang-Wei; Macia, Laurence; Feinle-Bisset, Christine

    2015-01-01

    The TGF-b superfamily cytokine MIC-1/GDF15 circulates in the blood of healthy humans. Its levels rise substantially in cancer and other diseases and this may sometimes lead to development of an anorexia/cachexia syndrome. This is mediated by a direct action of MIC-1/GDF15 on feeding centres...

  16. Clustering, haplotype diversity and locations of MIC-3: a unique root-specific defense-related gene family in upland cotton (Gossypium hirsutum L.)

    Science.gov (United States)

    MIC-3-related genes of cotton (Gossypium spp.) were identified and shown to have root-specific expression, associated with pathogen defense-related function and specifically increased expression in root-knot nematode (RKN) resistant plants after nematode infection. Here we cloned and sequenced MIC-...

  17. Stellar Winds and Dust Avalanches in the AU Mic Debris Disk

    Energy Technology Data Exchange (ETDEWEB)

    Chiang, Eugene; Fung, Jeffrey, E-mail: echiang@astro.berkeley.edu, E-mail: jeffrey.fung@berkeley.edu [Department of Astronomy, University of California at Berkeley, Campbell Hall, Berkeley, CA 94720-3411 (United States)

    2017-10-10

    We explain the fast-moving, ripple-like features in the edge-on debris disk orbiting the young M dwarf AU Mic. The bright features are clouds of submicron dust repelled by the host star’s wind. The clouds are produced by avalanches: radial outflows of dust that gain exponentially more mass as they shatter background disk particles in collisional chain reactions. The avalanches are triggered from a region a few au across—the “avalanche zone”—located on AU Mic’s primary “birth” ring at a true distance of ∼35 au from the star but at a projected distance more than a factor of 10 smaller: the avalanche zone sits directly along the line of sight to the star, on the side of the ring nearest Earth, launching clouds that disk rotation sends wholly to the southeast, as observed. The avalanche zone marks where the primary ring intersects a secondary ring of debris left by the catastrophic disruption of a progenitor up to Varuna in size, less than tens of thousands of years ago. Only where the rings intersect are particle collisions sufficiently violent to spawn the submicron dust needed to seed the avalanches. We show that this picture works quantitatively, reproducing the masses, sizes, and velocities of the observed escaping clouds. The Lorentz force exerted by the wind’s magnetic field, whose polarity reverses periodically according to the stellar magnetic cycle, promises to explain the observed vertical undulations. The timescale between avalanches, about 10 yr, might be set by time variability of the wind mass loss rate or, more speculatively, by some self-regulating limit cycle.

  18. Optical Coronagraphic Spectroscopy of AU Mic: Evidence of Time Variable Colors?

    Science.gov (United States)

    Lomax, Jamie R.; Wisniewski, John P.; Roberge, Aki; Donaldson, Jessica K.; Debes, John H.; Malumuth, Eliot M.; Weinberger, Alycia J.

    2018-02-01

    We present coronagraphic long slit spectra of AU Mic’s debris disk taken with the STIS instrument aboard the Hubble Space Telescope. Our spectra are the first spatially-resolved, scattered light spectra of the system’s disk, which we detect at projected distances between approximately 10 and 45 au. Our spectra cover a wavelength range between 5200 and 10200 Å. We find that the color of AU Mic’s debris disk is bluest at small (12–17 au) projected separations. These results both confirm and quantify the findings qualitatively noted by Krist et al. and are different than IR observations that suggested a uniform blue or gray color as a function of projected separation in this region of the disk. Unlike previous literature, which reported that the color of AU Mic’s disk became increasingly more blue as a function of projected separation beyond ∼30 au, we find the disk’s optical color between 35 and 45 au to be uniformly blue on the southeast side of the disk and decreasingly blue on the northwest side. We note that this apparent change in disk color at larger projected separations coincides with several fast, outward moving “features” that are passing through this region of the southeast side of the disk. We speculate that these phenomenon might be related and that the fast moving features could be changing the localized distribution of sub-micron-sized grains as they pass by, thereby reducing the blue color of the disk in the process. We encourage follow-up optical spectroscopic observations of AU Mic to both confirm this result and search for further modifications of the disk color caused by additional fast moving features propagating through the disk.

  19. Análisis de los problemas expresivos del cómic

    Directory of Open Access Journals (Sweden)

    José Luís RODRÍGUEZ BELTRÁN

    2009-11-01

    Full Text Available RESUMEN: Se plantea en este artículo una aproximación a los códigos específicos del cómic que busca principalmente determinar algunas de las relaciones existentes entre los mismos. No se busca, por lo tanto, definir cada uno de estos códigos, tarea ya realizada en numerosos trabajos más extensos que el presente artículo, sino buscar claves que permitan entender por qué algunas historietas presentan una narración fluida y otras, en cambio, resultan de lectura difícil y poco clara. El proceso que se siguió a este efecto fue la realización de un estudio estadístico sobre una muestra de cómics "de calidad". Los criterios para la selección de la muestra residieron fundamentalmente en la eliminación de subproductos, con la intención de dejar aisladas una serie de historietas narradas con efectividad. A continuación, una vez definida la muestra, se trató de convertir en variables bipolares todo aquello que, a juicio del autor y de las referencias consultadas, fuera de importancia como código específico o elemento significativo en una narración de viñetas. El resultado arroja cierta luz sobre la conveniencia o no de usar determinados recursos de modo conjunto, y podría resultar útil como marco de referencia flexible para aquellos interesados en conocer la gramática del cómic más allá de sus elementos constitutivos mínimos.ABSTRACT: This article sets forth an approach to the specific codes of the comic, in which the main aim is to determine some of the relationships existing between them. The objective is thus not to define each one of these codes - a task already performed in numerous studies, more extensive than this article, - but to find keys that will enable us to understand why some comic strips have a fluent series of incidents and others, on the contrary, are difficult to read and not very clear. The process foliowed for this purpose was that of carrying out a statistical study of a sample of "quality" comics. The

  20. Potentials of plasma NGAL and MIC-1 as biomarker(s in the diagnosis of lethal pancreatic cancer.

    Directory of Open Access Journals (Sweden)

    Sukhwinder Kaur

    Full Text Available Pancreatic cancer (PC is lethal malignancy with very high mortality rate. Absence of sensitive and specific marker(s is one of the major factors for poor prognosis of PC patients. In pilot studies using small set of patients, secreted acute phase proteins neutrophil gelatinase associated lipocalin (NGAL and TGF-β family member macrophage inhibitory cytokine-1 (MIC-1 are proposed as most potential biomarkers specifically elevated in the blood of PC patients. However, their performance as diagnostic markers for PC, particularly in pre-treatment patients, remains unknown. In order to evaluate the diagnostic efficacy of NGAL and MIC-1, their levels were measured in plasma samples from patients with pre-treatment PC patients (n = 91 and compared it with those in healthy control (HC individuals (n = 24 and patients with chronic pancreatitis (CP, n = 23. The diagnostic performance of these two proteins was further compared with that of CA19-9, a tumor marker commonly used to follow PC progression. The levels of all three biomarkers were significantly higher in PC compared to HCs. The mean (± standard deviation, SD plasma NGAL, CA19-9 and MIC-1 levels in PC patients was 111.1 ng/mL (2.2, 219.2 U/mL (7.8 and 4.5 ng/mL (4.1, respectively. In comparing resectable PC to healthy patients, all three biomarkers were found to have comparable sensitivities (between 64%-81% but CA19-9 and NGAL had a higher specificity (92% and 88%, respectively. For distinguishing resectable PC from CP patients, CA19-9 and MIC-1 were most specific (74% and 78% respectively. CA19-9 at an optimal cut-off of 54.1 U/ml is highly specific in differentiating resectable (stage 1/2 pancreatic cancer patients from controls in comparison to its clinical cut-off (37.1 U/ml. Notably, the addition of MIC-1 to CA19-9 significantly improved the ability to distinguish resectable PC cases from CP (p = 0.029. Overall, MIC-1 in combination with CA19-9 improved the diagnostic

  1. Efecto del EcoMic® en la emergencia de plántulas de Jatropha curcas (Nota Técnica Effect of EcoMic® on the emergence of Jatropha curcas seedlings (Technical Note

    Directory of Open Access Journals (Sweden)

    Yolai Noda

    2012-12-01

    Full Text Available Con el objetivo de estudiar el efecto del EcoMic® en la emergencia de las plántulas de Jatropha curcas, se hizo una prueba de observación en el laboratorio de análisis químico de la Estación Experimental de Pastos y Forrajes «Indio Hatuey». Se usaron semillas recién cosechadas, en dos tratamientos: semillas inoculadas con EcoMic® (T1, y sin inóculo (T2, con cuatro réplicas de 100 semillas cada una. Se utilizó un diseño totalmente aleatorizado y se realizaron 15 observaciones (a los 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15 y 16 días de emergencia. Las medias se compararon a través de un análisis descriptivo. El efecto del T1 fue notable durante todo el período; a partir del cuarto día se observaron 45 plántulas emergidas, lo que representó el 11,2% del total de las tratadas con este biofertilizante, y el último día del estudio había emergido el 96,2%. En el T2 no se observaron plántulas emergidas en ningún momento. Se concluye que el EcoMic® ejerció un efecto positivo en la emergencia de las plántulas de J. curcas al ser utilizado como inóculo en condiciones de laboratorio. Se recomienda realizar estudios pregerminativos para determinar la dormancia en la semilla de Jatropha, teniendo en cuenta el empleo del EcoMic® como uno de los tratamientos.In order to study the effect of EcoMic® on the emergence of Jatropha curcas seedlings, an observation test was conducted in the laboratory of chemical analysis of the Experimental Station of Pastures and Forages «Indio Hatuey». Newly-harvested seeds were used, in two treatments: seeds inoculated with EcoMic® (T1, and without inoculation (T2, with four replications of 100 seeds each. A completely randomized design was used and 15 observations were made (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15 and 16 days after emergence. The means were compared through a descriptive analysis. The effect of T1 was remarkable throughout the period; since the fourth day 45

  2. Concept medium programme

    DEFF Research Database (Denmark)

    Bjerrum, Peter

    2005-01-01

    The present essay is an attempt to determine the architectural project of the 21st century in relation to a modern conception of space as the medium of architecture, and of sociality as its program......The present essay is an attempt to determine the architectural project of the 21st century in relation to a modern conception of space as the medium of architecture, and of sociality as its program...

  3. Serum Levels of Human MIC-1/GDF15 Vary in a Diurnal Pattern, Do Not Display a Profile Suggestive of a Satiety Factor and Are Related to BMI.

    Directory of Open Access Journals (Sweden)

    Vicky Wang-Wei Tsai

    Full Text Available The TGF-b superfamily cytokine MIC-1/GDF15 circulates in the blood of healthy humans. Its levels rise substantially in cancer and other diseases and this may sometimes lead to development of an anorexia/cachexia syndrome. This is mediated by a direct action of MIC-1/GDF15 on feeding centres in the hypothalamus and brainstem. More recent studies in germline gene deleted mice also suggest that this cytokine may play a role in physiological regulation of energy homeostasis. To further characterize the role of MIC-1/GDF15 in physiological regulation of energy homeostasis in man, we have examined diurnal and food associated variation in serum levels and whether variation in circulating levels relate to BMI in human monozygotic twin pairs. We found that the within twin pair differences in serum MIC-1/GDF15 levels were significantly correlated with within twin pair differences in BMI, suggesting a role for MIC-1/GDF15 in the regulation of energy balance in man. MIC-1/GDF15 serum levels altered slightly in response to a meal, but comparison with variation its serum levels over a 24 hour period suggested that these changes are likely to be due to bimodal diurnal variation which can alter serum MIC-1/GDF15 levels by about plus or minus 10% from the mesor. The lack of a rapid and substantial postprandial increase in MIC-1/GDF15 serum levels suggests that MIC1/GDF15 is unlikely to act as a satiety factor. Taken together, our findings suggest that MIC-1/GDF15 may be a physiological regulator of energy homeostasis in man, most probably due to actions on long-term regulation of energy homeostasis.

  4. In Vitro Activity of Ertapenem versus Ceftriaxone against Neisseria gonorrhoeae Isolates with Highly Diverse Ceftriaxone MIC Values and Effects of Ceftriaxone Resistance Determinants: Ertapenem for Treatment of Gonorrhea?

    Science.gov (United States)

    Golparian, Daniel; Limnios, Athena; Whiley, David; Ohnishi, Makoto; Lahra, Monica M.; Tapsall, John W.

    2012-01-01

    Clinical resistance to the currently recommended extended-spectrum cephalosporins (ESCs), the last remaining treatment options for gonorrhea, is being reported. Gonorrhea may become untreatable, and new treatment options are crucial. We investigated the in vitro activity of ertapenem, relative to ceftriaxone, against N. gonorrhoeae isolates and the effects of ESC resistance determinants on ertapenem. MICs were determined using agar dilution technique or Etest for international reference strains (n = 17) and clinical N. gonorrhoeae isolates (n = 257), which included the two extensively drug-resistant (XDR) strains H041 and F89 and additional isolates with high ESC MICs, clinical ESC resistance, and other types of clinical high-level and multidrug resistance (MDR). Genetic resistance determinants for ESCs (penA, mtrR, and penB) were sequenced. In general, the MICs of ertapenem (MIC50 = 0.032 μg/ml; MIC90 = 0.064 μg/ml) paralleled those of ceftriaxone (MIC50 = 0.032 μg/ml; MIC90 = 0.125 μg/ml). The ESC resistance determinants mainly increased the ertapenem MIC and ceftriaxone MIC at similar levels. However, the MIC ranges for ertapenem (0.002 to 0.125 μg/ml) and ceftriaxone (gonorrhea, particularly for the currently identified ESC-resistant cases and possibly in a dual antimicrobial therapy regimen. However, further knowledge regarding the genetic determinants (and their evolution) conferring resistance to both antimicrobials, and clear correlates between genetic and phenotypic laboratory parameters and clinical treatment outcomes, is essential. PMID:22547617

  5. APD Properties and Recovery from Radiation Damage

    CERN Document Server

    Baccaro, Stefania; Caruso, S; Cavallari, Francesca; Dafinei, Ioan; Diemoz, Marcella; Emeliantchik, Igor; Festinesi, Armando; Longo, Egidio; Montecchi, Marco; Organtini, Giovanni; Rosi, G

    1997-01-01

    Avalanche photodiodes will be used to detect scintillation light from PWO crystals in the CMS electromagnetic calorimeter. Properties of Hamamatsu APD are reported special attention has been devoted to the study of radiation hardness and room temperature annealing. We found a fast recovery with a time constant of 1.3 days a medium fast recovery with a lifetime of the order of 10 days and indication of a third component with very long time constant of the order of 300 days.

  6. Cómo, cuándo y por qué hicimos un cómic bollo

    Directory of Open Access Journals (Sweden)

    Gema Arquero (Project Manager

    2009-01-01

    Full Text Available Este artículo traza un recorrido por distintos aspectos que desempeñaron un papel destacado en la génesis del cómic Salidas de Emergencia. Sus autoras explican la importancia que su situación personal y el contexto político de la España de 2005 tuvieron en la decisión de iniciar su proyecto creativo, situándonos a la vez en las coordenadas culturales en que éste se inscribe. Con ello, también se lleva a cabo un repaso por distintos productos culturales de temática lésbica, con el que se ponen en evidencia las particularidades de este cómic.

  7. Sucralose Increases Antimicrobial Resistance and Stimulates Recovery of Escherichia coli Mutants.

    Science.gov (United States)

    Qu, Yilin; Li, Rongyan; Jiang, Mingshan; Wang, Xiuhong

    2017-07-01

    Because of heavy use of antimicrobials, antimicrobial resistance in bacteria has become of great concern. The effect of some widely used food additives such as sucralose on bacteria in the gut and the environment has also drawn increasing attention. In this study, we investigated the interaction between antimicrobials and sucralose impacting antimicrobial resistance and mutation of Escherichia coli (E. coli). To examine antimicrobial resistance and mutation frequency, different subinhibitory concentrations of sucralose were added to cultures of E.coli BW25113 that were then treated with antimicrobials, oxolinic acid, or moxifloxacin. Then the E.coli were assayed for bacterial survival and recovery of mutants resistant to an unrelated antimicrobial, rifampicin. Pre-treatment of E.coli BW25113 with 1/2 minimal inhibitory concentration (MIC) of sucralose increased the survival rate in oxolinic acid or moxifloxacin. A 1/3 MIC of sucralose increased rifampicin-resistant mutation rate of E.coli BW25113 after 72 h, while rifampicin-resistant mutation rate was increased when co-treated with 1/8 MIC, 1/4 MIC, 1/3 MIC sucralose, and oxolinic acid after 24 h. Sucralose can increase the antimicrobial resistance and mutation frequency of E.coli to some antimicrobials.

  8. Postantibiotic effect and postantibiotic sub-MIC effect of LTX-109 and mupirocin on Staphylococcus aureus blood isolates.

    Science.gov (United States)

    Saravolatz, L D; Pawlak, J; Martin, H; Saravolatz, S; Johnson, L; Wold, H; Husbyn, M; Olsen, W M

    2017-11-01

    The development of new synthetic antimicrobial peptides like LTX-109 provides a new class of drugs for the treatment of Staphylococcus aureus infections. We evaluated LTX-109 and mupirocin for pharmacodynamic parameters against 10 methicillin-resistant S. aureus isolates. The postantibiotic effect (PAE) is defined as the length of time that bacterial growth is suppressed following a brief exposure to an antibiotic. We also determined the sub-MIC effect (SME) which measures the direct effect of subinhibitory levels on strains that have not previously been exposed to antibiotics. The postantibiotic sub-MIC effect (PA-SME) is a combination of the PAE and SME. LTX-109 had an average PAE of 5·51 h vs 1·04 h for mupirocin. The PA-SME of LTX-109 ranged from 2·51 to 9·33 h as the concentration increased from 0·2 to 0·4 times the minimal inhibitory concentration (MIC). The PA-SME range for mupirocin was 0·93-2·58 h. LTX-109, as compared to mupirocin, demonstrated prolonged time of effect for these pharmacodynamic parameters, which supports persistent activity for several hours after the drug is no longer present or is below the MIC. The pharmacodynamic parameters studied here suggest that LTX-109 is less likely than mupirocin to generate resistance to S. aureus. Resistant bacterial infections continue to be a challenge for clinicians. Identification of antibiotics with pharmacodynamic advantages may be beneficial in the treatment of these infections. An antibiotic with a longer postantibiotic effect may be able to be administered less frequently resulting in improved adherence. In this study, a new synthetic antimicrobial peptide, LTX-109, demonstrated a more prolonged time for LTX-109 than mupirocin against methicillin-resistant Staphylococcus aureus. © 2017 The Society for Applied Microbiology.

  9. Webgrafia al voltant del ciberplagi. Referències a la xarxa sobre el ciberplagi acadèmic

    Directory of Open Access Journals (Sweden)

    Jaume Sureda

    2008-12-01

    Full Text Available En aquest article es proporcionen les fonts de documentació que hi ha a internet i que poden aportar al lector que hi estigui interessat un coneixement més profund de qualsevol de les cares, les arestes i els vèrtexs del polièdric fenomen del plagi acadèmic entre l'alumnat. Text complet (PDFDossier complet (PDF

  10. Optimizing the updated Goddard shortwave radiation Weather Research and Forecasting (WRF) scheme for Intel Many Integrated Core (MIC) architecture

    Science.gov (United States)

    Mielikainen, Jarno; Huang, Bormin; Huang, Allen H.-L.

    2015-05-01

    Intel Many Integrated Core (MIC) ushers in a new era of supercomputing speed, performance, and compatibility. It allows the developers to run code at trillions of calculations per second using the familiar programming model. In this paper, we present our results of optimizing the updated Goddard shortwave radiation Weather Research and Forecasting (WRF) scheme on Intel Many Integrated Core Architecture (MIC) hardware. The Intel Xeon Phi coprocessor is the first product based on Intel MIC architecture, and it consists of up to 61 cores connected by a high performance on-die bidirectional interconnect. The co-processor supports all important Intel development tools. Thus, the development environment is familiar one to a vast number of CPU developers. Although, getting a maximum performance out of Xeon Phi will require using some novel optimization techniques. Those optimization techniques are discusses in this paper. The results show that the optimizations improved performance of the original code on Xeon Phi 7120P by a factor of 1.3x.

  11. Measuring coverage in MNCH: tracking progress in health for women and children using DHS and MICS household surveys.

    Directory of Open Access Journals (Sweden)

    Attila Hancioglu

    Full Text Available Household surveys are the primary data source of coverage indicators for children and women for most developing countries. Most of this information is generated by two global household survey programmes-the USAID-supported Demographic and Health Surveys (DHS and the UNICEF-supported Multiple Indicator Cluster Surveys (MICS. In this review, we provide an overview of these two programmes, which cover a wide range of child and maternal health topics and provide estimates of many Millennium Development Goal indicators, as well as estimates of the indicators for the Countdown to 2015 initiative and the Commission on Information and Accountability for Women's and Children's Health. MICS and DHS collaborate closely and work through interagency processes to ensure that survey tools are harmonized and comparable as far as possible, but we highlight differences between DHS and MICS in the population covered and the reference periods used to measure coverage. These differences need to be considered when comparing estimates of reproductive, maternal, newborn, and child health indicators across countries and over time and we discuss the implications of these differences for coverage measurement. Finally, we discuss the need for survey planners and consumers of survey results to understand the strengths, limitations, and constraints of coverage measurements generated through household surveys, and address some technical issues surrounding sampling and quality control. We conclude that, although much effort has been made to improve coverage measurement in household surveys, continuing efforts are needed, including further research to improve and refine survey methods and analytical techniques.

  12. LiF Reduces MICs of Antibiotics against Clinical Isolates of Gram-Positive and Gram-Negative Bacteria

    Directory of Open Access Journals (Sweden)

    H. C. Syed

    2012-01-01

    Full Text Available Antibiotic resistance is an ever-growing problem yet the development of new antibiotics has slowed to a trickle, giving rise to the use of combination therapy to eradicate infections. The purpose of this study was to evaluate the combined inhibitory effect of lithium fluoride (LiF and commonly used antimicrobials on the growth of the following bacteria: Enterococcus faecalis, Staphyloccoccus aureus, Escherichia coli, Pseudomonas aeruginosa, Acinetobacter baumannii, Klebsiella pneumoniae, Serratia marcescens, and Streptococcus pneumoniae. The in vitro activities of ceftazidime, sulfamethoxazole-trimethoprim, streptomycin, erythromycin, amoxicillin, and ciprofloxacin, doxycycline, alone or combined with LiF were performed by microdilution method. MICs were determined visually following 18–20 h of incubation at 37°C. We observed reduced MICs of antibiotics associated with LiF ranging from two-fold to sixteen-fold. The strongest decreases of MICs observed were for streptomycin and erythromycin associated with LiF against Acinetobacter baumannii and Streptococcus pneumoniae. An eight-fold reduction was recorded for streptomycin against S. pneumoniae whereas an eight-fold and a sixteen-fold reduction were obtained for erythromycin against A. baumannii and S. pneumoniae. This suggests that LiF exhibits a synergistic effect with a wide range of antibiotics and is indicative of its potential as an adjuvant in antibiotic therapy.

  13. De los cómics a la cinematografía = From Comics to Cinematography

    Directory of Open Access Journals (Sweden)

    Román Gubern Garriga-Nogués

    2015-06-01

    Full Text Available Desde una perspectiva multidisciplinar nos sumergimos en la Historia del Arte para bucear en los antecedentes del cómic y, a partir de ahí, seguir a lo largo del tiempo la interacción que ha existido entre éste y los grandes medios de difusión de imágenes y de creación de iconos visuales: pintura, fotografía y especialmente el cine. Analiza el paso de la imagen estática a la imagen en movimiento tanto en la alta cultura como en la cultura popular y como todas estas artes visuales se han interrelacionado y retroalimentado, mucho más aún en la actualidad. Un largo recorrido que tiene por objeto rastrear los procesos, la dinámica y la evolución que existe alrededor de la viñeta desde sus orígenes ancestrales hasta el mundo del cine, sus semejanzas y sus diferencias, su interactividad y, sobre todo la influencia y los nexos existentes entre uno y otro en la búsqueda y desarrollo de un lenguaje plástico narrativo.From a multidisciplinary perspective we immerse ourselves into the History of Art, to dive into the background of the history of comics and, from there, to follow along the way the interaction that has existed between this and the main media that are specialized in images and creating visual icons, painting, photography and especially the cinema. It analyses the step from the static image to the moving image, in both high culture and popular culture, and shows how all these visual arts have been interrelating and have nurtured themselves, even more so nowadays. A long journey that aims to track the processes, the dynamic and the evolution that exist around the vignette from their ancestral origins to the cinematic world, their similarities and their differences, its interactivity and especially the influence and links between one another in the pursuit and development of a narrative visual language.

  14. The Interstellar Medium

    CERN Document Server

    Lequeux, James

    2005-01-01

    Describing interstellar matter in our galaxy in all of its various forms, this book also considers the physical and chemical processes that are occurring within this matter. The first seven chapters present the various components making up the interstellar matter and detail the ways that we are able to study them. The following seven chapters are devoted to the physical, chemical and dynamical processes that control the behaviour of interstellar matter. These include the instabilities and cloud collapse processes that lead to the formation of stars. The last chapter summarizes the transformations that can occur between the different phases of the interstellar medium. Emphasizing methods over results, "The Interstellar Medium" is written for graduate students, for young astronomers, and also for any researchers who have developed an interest in the interstellar medium.

  15. Optical recording medium

    International Nuclear Information System (INIS)

    Andriech, A.; Bivol, V.; Tridukh, G.; Tsiuleanu, D.

    2002-01-01

    The invention relates of the micro- and optoelectronics, computer engineering ,in particular, to tjhe optical information media and may be used in hilography. Summary of the invention consists in that the optical image recording medium, containing a dielectric substrates, onto one surface of which there are placed in series a transparent electricity conducting layer, a photo sensitive recording layer of chalcogenic glass and a thin film electrode of aluminium, is provided with an optically transparent protective layer, applied into the thin film electrode. The result of the invention consists in excluding the dependence of chemical processes course into the medium upon environmental conditions

  16. The anorectic actions of the TGFβ cytokine MIC-1/GDF15 require an intact brainstem area postrema and nucleus of the solitary tract.

    Directory of Open Access Journals (Sweden)

    Vicky Wang-Wei Tsai

    Full Text Available Macrophage inhibitory cytokine-1 (MIC-1/GDF15 modulates food intake and body weight under physiological and pathological conditions by acting on the hypothalamus and brainstem. When overexpressed in disease, such as in advanced cancer, elevated serum MIC-1/GDF15 levels lead to an anorexia/cachexia syndrome. To gain a better understanding of its actions in the brainstem we studied MIC-1/GDF15 induced neuronal activation identified by induction of Fos protein. Intraperitoneal injection of human MIC-1/GDF15 in mice activated brainstem neurons in the area postrema (AP and the medial (m portion of the nucleus of the solitary tract (NTS, which did not stain with tyrosine hydroxylase (TH. To determine the importance of these brainstem nuclei in the anorexigenic effect of MIC-1/GDF15, we ablated the AP alone or the AP and the NTS. The latter combined lesion completely reversed the anorexigenic effects of MIC-1/GDF15. Altogether, this study identified neurons in the AP and/or NTS, as being critical for the regulation of food intake and body weight by MIC-1/GDF15.

  17. Macrophage Inhibitory Cytokine-1 (MIC-1 as A Biomarker for Diagnosis 
and Prognosis of Stage I-II Non-small Cell Lung Cancer

    Directory of Open Access Journals (Sweden)

    Yuning LIU

    2016-04-01

    Full Text Available Background and objective Increased macrophage inhibitory cytokine-1 (MIC-1, member of transforming growth factor-β (TGF-β superfamily, was found in patients serum with epithelial tumors. Therefore, our aim was to delineate the diagnostic and prognostic value of serum MIC-1 in patients with stage I-II non-small cell lung cancer (NSCLC. Methods A total of 152 consecutive patients with stage I–II NSCLC were prospectively enrolled and underwent follow up after total resection of tumor. Serum MIC-1 level was detected in lung cancer patients by ELISA, 48 benign pulmonary disease patients and 105 healthy controls, and was correlated with clinical features and prognosis of patients. Results The level of MIC-1 of NSCLC patients was significantly higher than that of controls (P<0.001 and benign pulmonary disease patients (P<0.001. A threshold of 1,000 pg/mL could be used to diagnose early-stage NSCLC with 70.4% sensitivity and 99.0% specificity. The level of MIC-1 was associated with elder age (P=0.001, female (P=0.03 and T2 (P=0.022. A threshold of 1,465 pg/mL could identify patients with early poor outcome with 72.2% sensitivity and 66.1% specificity. The overall 3-year survival rate in patients with high level of MIC-1 (≥1,465 pg/mL was significantly lower than that of patients with low MIC-1 level (77.6% vs 94.8%. Multivariable Cox regression revealed that a high level of MIC-1 was an independent risk factor for compromised overall survival (HR=3.37, 95%CI: 1.09-10.42, P=0.035. Conclusion High level of serum MIC-1 could be served as a potential biomarker for diagnosis and poorer outcome in patients with early-stage NSCLC.

  18. Disaster Debris Recovery Database - Recovery

    Science.gov (United States)

    The US EPA Region 5 Disaster Debris Recovery Database includes public datasets of over 6,000 composting facilities, demolition contractors, transfer stations, landfills and recycling facilities for construction and demolition materials, electronics, household hazardous waste, metals, tires, and vehicles in the states of Illinois, Indiana, Iowa, Kentucky, Michigan, Minnesota, Missouri, North Dakota, Ohio, Pennsylvania, South Dakota, West Virginia and Wisconsin.In this update, facilities in the 7 states that border the EPA Region 5 states were added to assist interstate disaster debris management. Also, the datasets for composters, construction and demolition recyclers, demolition contractors, and metals recyclers were verified and source information added for each record using these sources: AGC, Biocycle, BMRA, CDRA, ISRI, NDA, USCC, FEMA Debris Removal Contractor Registry, EPA Facility Registry System, and State and local listings.

  19. Comparrisson of MICs of ceftioufur and other antimicrobial agents against bacterial pathogens of swine from the United States, Canada and Denmark

    DEFF Research Database (Denmark)

    Salmon, S.A.; Watts, J.L.; Case, C.A.

    1995-01-01

    , sulfamethazine, trimethoprim-sulfadiazine (1:19), erythromycin, lincomycin, spectinomycin, lincomycin-spectinomycin (1:8), tilmicosin, and tetracycline. Tilmicosin was only tested against the U.S. isolates. Overall, ceftiofur and enrofloxacin were the most active antimicrobial agents tested against all isolates.......0 and 8.0 mu g/ml, respectively). However, this compound was not active against the remaining U.S. isolates (MIC(90)s, >64.0 mu g/ml), Differences in the MICs from one country to another were not detected with enrofloxacin, ceftiofur, or lincomycin for the strains tested, but variations in the MICs...

  20. Comparison of EUCAST and CLSI Reference Microdilution MICs of Eight Antifungal Compounds for Candida auris and Associated Tentative Epidemiological Cutoff Values

    DEFF Research Database (Denmark)

    Arendrup, M. C.; Prakash, Anupam; Meletiadis, Joseph

    2017-01-01

    ) and lowest for isavuconazole and anidulafungin (58%/76% to 75% within ±1/±2 dilutions). We found that 90.2%/100% of the isolates were amphotericin B susceptible based on CLSI/EUCAST methods, respectively (i.e., with MICs of ≤1 mg/liter), and 100%/97.6% were fluconazole nonsusceptible by CLSI/EUCAST (MICs > 2......, the estimated ECOFFs were dependent on the method applied for voriconazole (1 to 32) and isavuconazole (0.125 to 4). CLSI and EUCAST MICs were remarkably similar and confirmed uniform fluconazole resistance and variable acquired resistance to the other agents....

  1. Roentgen contrast medium

    International Nuclear Information System (INIS)

    Tamborski, C.

    1989-01-01

    The patent deals with a roentgen contrast medium containing a perfluorinebrominealkylether of the formula C m F 2m+1 OC n F 2n Br dispersed in water, preferentially in the presence of a non-ionic dispersing agent such as a fluorinated amidoaminoxide. 2 tabs

  2. Radon in geological medium

    Energy Technology Data Exchange (ETDEWEB)

    Hricko, J [GEOCOMPLEX, a.s., Bratislava (Slovakia)

    1996-12-31

    The paper presented deals with behavior of the radon in geological medium and with some results of the radon survey in Bratislava and Kosice regions. 1) The a{sub v} has been detected in the holes 0.80 m deep. The density of observations - 3 reference areas (one represents 20 stations) per 1 km{sup 2}. The radon risk maps in 1:25000 and 1:50000 scales have been compiled. The 56.8% of the project area lies in low radon risk, 37.6% in medium radon risk and 5.6% in high radon risk. Follow-up monitoring of the equivalent volume radon activity (EVRA) at the flats, located in the areas with high radon risk of the surface layer, has showed values several times higher than Slovak limits (Marianka, Raca, Vajnory). The evidence that neotectonic is excellent medium for rising up emanation to the subsurface layer, is shown on the map. The tectonic zone of Liscie udolie in Bratislava-Karlova Ves area has been clearly detected by profile radon survey (a{sub v} > 50 kBq/m{sup 3}). 2) At present, northern half of the area of Kosice in question was covered by radon survey. The low and medium radon risks have been observed here, while localities with high radon risk are small in extent. The part of radon risk and soil permeability map from northern Kosice area is shown. (J.K.) 3 figs., 2 refs.

  3. Radon in geological medium

    International Nuclear Information System (INIS)

    Hricko, J.

    1995-01-01

    The paper presented deals with behavior of the radon in geological medium and with some results of the radon survey in Bratislava and Kosice regions. 1) The a v has been detected in the holes 0.80 m deep. The density of observations - 3 reference areas (one represents 20 stations) per 1 km 2 . The radon risk maps in 1:25000 and 1:50000 scales have been compiled. The 56.8% of the project area lies in low radon risk, 37.6% in medium radon risk and 5.6% in high radon risk. Follow-up monitoring of the equivalent volume radon activity (EVRA) at the flats, located in the areas with high radon risk of the surface layer, has showed values several times higher than Slovak limits (Marianka, Raca, Vajnory). The evidence that neotectonic is excellent medium for rising up emanation to the subsurface layer, is shown on the map. The tectonic zone of Liscie udolie in Bratislava-Karlova Ves area has been clearly detected by profile radon survey (a v > 50 kBq/m 3 ). 2) At present, northern half of the area of Kosice in question was covered by radon survey. The low and medium radon risks have been observed here, while localities with high radon risk are small in extent. The part of radon risk and soil permeability map from northern Kosice area is shown. (J.K.) 3 figs., 2 refs

  4. Les etapes d’édification de la fortification de Horodca Mică

    Directory of Open Access Journals (Sweden)

    Octavian Munteanu

    2013-12-01

    Full Text Available La fortification Horodca Mică est située dans la zone centrale de l'espace pruto-dniesterien, aux environs des sources de la rivière Botna, et elle est devenue objet des recherches systématiques depuis 2006. Plusieurs des résultats obtenus depuis cette date on été publiés entre temps. On compte parmi ceux-ci une étude concernant les éléments défensifs de la forteresse, où l'on a mis en avant l'hypothèse d'une fortification par étapes, du promontoire, alternées avec des destructions périodiques. Au départ, on avait plus insisté sur la première phase d'édification du système défensif, en décrivant ses éléments constitutifs, les techniques utilisées dans le processus d'édification, mais aussi l'évolution de la fortification même, jusqu'au dévastateur incendie qui a écroulé la construction défensive. Dans cet article on a repris le débat portant sur le système défensif. L'hypothèse sur laquelle on se fonde admet l'existence de trois autres phases de refortification du même espace, suite à la première destruction. Pour l'argumentaire de ce point de vue on s'est proposé de présenter dans un premier temps, le tableau des observations objectives, enregistrées sur le terrain, et dans un deuxième temps, partant de ces observations, offrir une explication de la vision que nous avons construit. Cette analyse porte y compris sur les modalités d'édification du système défensif dans chacune des phases identifiées, sur les techniques et matériaux utilisés, ainsi que des raisonnements concernant les repères chronologiques. On est donc d'avis que dans ces phases ultérieures de fortification du promontoire, a été procédé de la même manière que dans la première : un fossé a été creusé (en réalité c'est l'ancien qui a été étendu en largeur, derrière a été montée une palissade complexe, en bois (sur le sommet même de la vague constituée suite à l'écroulement de la construction de la phase

  5. Antimicrobial evaluation of new metallic complexes with xylitol active against P. aeruginosa and C. albicans: MIC determination, post-agent effect and Zn-uptake.

    Science.gov (United States)

    Santi, E; Facchin, G; Faccio, R; Barroso, R P; Costa-Filho, A J; Borthagaray, G; Torre, M H

    2016-02-01

    Xylitol (xylH5) is metabolized via the pentose pathway in humans, but it is unsuitable as an energy source for many microorganisms where it produces a xylitol-induced growth inhibition and disturbance in protein synthesis. For this reason, xylitol is used in the prophylaxis of several infections. In the search of better antimicrobial agents, new copper and zinc complexes with xylitol were synthesized and characterized by analytical and spectrosco pic methods: Na2[Cu3(xylH−4)2]·NaCl·4.5H2O (Cu-xyl) and [Zn4(xylH−4)2(H2O)2]·NaCl·3H2O (Zn-xyl). Both copper and zinc complexes presented higher MIC against Pseudomona aeruginosa than the free xylitol while two different behaviors were found against Candida albicans depending on the complex. The growth curves showed that Cu-xyl presented lower activity than the free ligand during all the studied period. In the case of Znxyl the growth curves showed that the inhibition of the microorganism growth in the first stage was equivalent to that of xylitol but in the second stage (after 18 h) Zn-xyl inhibited more. Besides, the PAE (post agent effect)obtained for Zn-xyl and xyl showed that the recovery from the damage of microbial cells had a delay of 14 and 13 h respectively. This behavior could be useful in prophylaxis treatments for infectious diseases where it is important that the antimicrobial effect lasts longer. With the aim to understand the microbiological activities the analysis of the particle size, lipophilicity and Zn uptake was performed.

  6. El cómic como fuente histórica : el falso testimonio de Tintín en el Congo Belga

    Directory of Open Access Journals (Sweden)

    Óscar Gual Boronat

    2011-01-01

    Full Text Available A través del estudio de la obra Tintin au Congo del dibujante belga Hergé, tratamos de probar la capacidad del cómic para ser utilizado como fuente histórica. La actual definición de fuente puede englobarlo perfectamente pero es necesaria una demostración práctica. Tras contextualizar dicha historieta pasamos a realizar una lectura atenta de la misma, así como de sus aspectos más polémicos, para a continuación describir el proceso de trabajo del propio Hergé y las influencias de su entorno. Por último, entraremos a debatir cuál es el origen de la historieta como medio y cuál es el método de análisis a la hora de interrogarla históricamente.Through the study of the Belgian cartoonist Hergé's work Tintin au Congo we try to test the ability of comics to be used as a historical source. The current source definition can cover it very well but requires a practical demonstration. After we contextualize this story we make a careful reading of it and of its most controversial features, then we describe the process of Hergé's own work and the influences of their environment. Finally we enter into a discussion about which is the origin of comics as a medium and which is the method of analysis when questioning historically.

  7. Dielectric recovery mechanism of pressurized carbon dioxide at liquid and supercritical phases

    Science.gov (United States)

    Tanoue, Hiroyuki; Furusato, Tomohiro; Imamichi, Takahiro; Ota, Miyuki; Katsuki, Sunao; Akiyama, Hidenori

    2015-09-01

    Estimates of dielectric recovery rates of supercritical (SC) and liquid carbon dioxide (CO2) were derived with focus on highly-repetitive pulsed power switching mediums. Calculated results suggest that recovery time of SC and liquid CO2 are approximately 50 times shorter than that of water and oils. Prior to 10 µs after breakdown, recovery rates in neither SC nor liquid CO2 reached 100%, though the recovery rate in SC CO2 was higher than that of liquid CO2. To examine causes of recovery rate differences, each dielectric recovery process in SC and liquid CO2 was observed by laser shadowgraph technique. These shadowgraph images suggest two factors explaining dielectric recovery rate differences between these medium conditions: 1) thermodynamic property differences between medium conditions, and 2) differences in the low density region recovery mechanism.

  8. 3D-Spiral Small Antenna Design and Realization for Biomedical Telemetry in the MICS band

    Directory of Open Access Journals (Sweden)

    A. K. Skrivervik

    2009-12-01

    Full Text Available This work presents the design and realization procedure of small implantable antenna for biotelemetry applications. The radiator occupies a volume smaller than 3 cm3 (without its biocompatible insulation, is well matched within the Medical Implanted Communications System band and shows an adequate gain (-28.5 dB while introduced in the appropriate equivalent body medium. The latter is a homogeneous phantom with muscle dielectric properties. A prototype has been manufactured and measurements agree with theoretical predictions. Particular attention is paid to the building requirements such as the presence of glue. Specific Absorption Rate (SAR distribution has been computed evaluating the maximum power deliverable to the antenna in order to respect the regulated SAR limitation.

  9. Sobre el plagi acadèmic a Europa. Un enfocament analític basat en quatre estudis

    Directory of Open Access Journals (Sweden)

    Vanja Pupovac

    2008-12-01

    Full Text Available Amb el desenvolupament de les tecnologies de la informació i la comunicació (TIC, el plagi esdevé un problema cada cop més greu en la comunitat acadèmica. Segons els estudis sobre el plagi acadèmic elaborats en universitats de quatre països europeus diferents, l'índex de plagi entre els estudiants és considerablement alt i els estudiants majoritàriament passen per alt o permeten el plagi per la manca de coneixement, la manca de conseqüències o simplement perquè les TIC fan que el plagi sigui fàcil de cometre. Les conclusions dels estudis que es presenten en aquest article indiquen que cal introduir polítiques estrictes contra el plagi a les universitats. Pensem que s'hauria de captar l'atenció del públic sobre el problema del plagi, que s'hauria de debatre en altes esferes i que s'haurien d'aplicar mesures efectives contra el plagi. L'abast del plagi entre estudiants i les seves actituds envers el plagi reben influències de l'entorn cultural i també per l'escenari acadèmic. En comunitats multiculturals, com ara la comunitat europea, és necessari investigar i comparar el comportament acadèmic a diferents països per a establir estàndards equivalents en l'ensenyament arreu d'Europa. Text complet (PDFDossier complet (PDF

  10. Concept medium program

    DEFF Research Database (Denmark)

    Bjerrum, Peter

    2003-01-01

    The present essays is an attempt to dertermine the architecural project of the 21st century in realation to a modern conception of space as the medium of architecture, and of society as its program. This attempt adopts the internal point of view of an architect in describing a modern architectural...... project within the framework: concept - program, these notions being concieved as spatial representations primarily and immediately "given" to architecture....

  11. Field experiences using acrolein (2-propenal) for control of SRB and MIC in an offshore production flowline and onshore production facility in Western Australia

    Energy Technology Data Exchange (ETDEWEB)

    Shield, M.; Charlesworth, M.; Paakkonen, S.

    2006-03-15

    Acrolein, 2-propenal, was evaluated as a microbiocide for control of sulphate-reducing bacteria (SRB) in a sub-sea pipeline and an onshore process plant operated by ChevronTexaco Australia Pty Ltd (CVX) in the North West Shelf (NWS) of Australia. An initial trial compared the efficacy of acrolein with that of a glutaraldehyde, quaternary amine blend (GQB) for control of SRB implicated in microbiologically induced corrosion (MIC) of the sub-sea pipeline. Based on improved performance, acrolein subsequently replaced the GQB for routine microbiocide treatment of the pipeline. In addition, a plant trial assessed the impact of acrolein supplementation of the existing tetrakishydroxy-methyl phosphonium sulphate (THPS) microbiocide programme for control of SRB in process plant operations. This paper overviews both the pipeline and plant trials as well as the programme implementation of acrolein microbiocide for routine pipeline treatment. In addition to an improved performance and safety profile, complete conversion of the microbiocide programme to acrolein is projected to result in direct savings of 40%, with further potential for secondary operational cost savings. on behalf of Ampol and Caltex; and, in 1964, the company discovered oil in commercial quantities on Barrow Island (BWI) off the North West Shelf of Australia. Today, CVX continues hydrocarbon production operations on BWI with over 300 million barrels produced since inception. BWI volumes have been augmented since 1989 through hydrocarbon recovery operations near Thevenard Island (TVI), a small island located 25 km north-north west of Onslow. To date, more than 146 million barrels have been processed through facilities on TVI. With the process plant covering only a small corner of the island, the majority of land mass on TVI is classified as a nature reserve for the protection of plants and animals. Important wildlife found on the island include green and flatback turtles that nest on the islands beaches. In

  12. Dual Regulation of the Small RNA MicC and the Quiescent Porin OmpN in Response to Antibiotic Stress in Escherichia coli

    Directory of Open Access Journals (Sweden)

    Sushovan Dam

    2017-12-01

    Full Text Available Antibiotic resistant Gram-negative bacteria are a serious threat for public health. The permeation of antibiotics through their outer membrane is largely dependent on porin, changes in which cause reduced drug uptake and efficacy. Escherichia coli produces two major porins, OmpF and OmpC. MicF and MicC are small non-coding RNAs (sRNAs that modulate the expression of OmpF and OmpC, respectively. In this work, we investigated factors that lead to increased production of MicC. micC promoter region was fused to lacZ, and the reporter plasmid was transformed into E. coli MC4100 and derivative mutants. The response of micC–lacZ to antimicrobials was measured during growth over a 6 h time period. The data showed that the expression of micC was increased in the presence of β-lactam antibiotics and in an rpoE depleted mutant. Interestingly, the same conditions enhanced the activity of an ompN–lacZ fusion, suggesting a dual transcriptional regulation of micC and the quiescent adjacent ompN. Increased levels of OmpN in the presence of sub-inhibitory concentrations of chemicals could not be confirmed by Western blot analysis, except when analyzed in the absence of the sigma factor σE. We suggest that the MicC sRNA acts together with the σE envelope stress response pathway to control the OmpC/N levels in response to β-lactam antibiotics.

  13. Comparative Effectiveness of Vancomycin Versus Daptomycin for MRSA Bacteremia With Vancomycin MIC >1 mg/L: A Multicenter Evaluation.

    Science.gov (United States)

    Moise, Pamela A; Culshaw, Darren L; Wong-Beringer, Annie; Bensman, Joyce; Lamp, Kenneth C; Smith, Winter J; Bauer, Karri; Goff, Debra A; Adamson, Robert; Leuthner, Kimberly; Virata, Michael D; McKinnell, James A; Chaudhry, Saira B; Eskandarian, Romic; Lodise, Thomas; Reyes, Katherine; Zervos, Marcus J

    2016-01-01

    Clinical studies comparing vancomycin with alternative therapy for methicillin-resistant Staphylococcus aureus (MRSA) bacteremia are limited. The objective of this study was to compare outcomes of early daptomycin versus vancomycin treatment for MRSA bacteremia with high vancomycin MICs in a geographically diverse multicenter evaluation. This nationwide, retrospective, multicenter (N = 11), matched, cohort study compared outcomes of early daptomycin with vancomycin for MRSA bloodstream infection (BSI) with vancomycin MICs 1.5 to 2 µg/mL. Matching variables, based on propensity regression analysis, included age, intensive care unit (ICU), and type of BSI. Outcomes were as follows: (1) composite failure (60-day all-cause mortality, 7-day clinical or microbiologic failure, 30-day BSI relapse, or end-of-treatment failure (EOT; discontinue/change daptomycin or vancomycin because of treatment failure or adverse event]); (2) nephrotoxicity; and (2) day 4 BSI clearance. A total of 170 patients were included. The median (interquartile range) age was 60 years (50-74); the median (range) Acute Physiology and Chronic Health Evaluation II score was 15 (10-18); 31% were in an ICU; and 92% had an infectious disease consultation. BSI types included endocarditis/endovascular (39%), extravascular (55%), and central catheter (6%). The median daptomycin dose was 6 mg/kg, and the vancomycin trough level was 17 mg/L. Overall composite failure was 35% (59 of 170): 15% due to 60-day all-cause mortality, 14% for lack of clinical or microbiologic response by 7 days, and 17% due to failure at end of therapy (discontinue/change because of treatment failure or adverse event). Predictors of composite failure according to multivariate analysis were age >60 years (odds ratio, 3.7; P day 4 bacteremia clearance rates for immunocompromised patients (n = 26) (94% vs 56% for daptomycin vs vancomycin; P = 0.035). Results from this multicenter study provide, for the first time, a geographically diverse

  14. System i Disaster Recovery Planning

    CERN Document Server

    Dolewski, Richard

    2008-01-01

    Mapping out all the preparations necessary for an effective disaster recovery plan and its safeguard-a continuous maintenance program-this guide is aimed at IT managers of small and medium businesses. The opening section covers the initial steps of auditing vulnerability, ranking essential IT functions, and reviewing the storage of tape backups, with the following discussion focused on the elements of the plan itself. The plan includes a mission statement, a definition of disaster, the assignment of staff to teams, methods of compensating for human error, and standards for documenting the step

  15. Performance Analysis of GFDL's GCM Line-By-Line Radiative Transfer Model on GPU and MIC Architectures

    Science.gov (United States)

    Menzel, R.; Paynter, D.; Jones, A. L.

    2017-12-01

    Due to their relatively low computational cost, radiative transfer models in global climate models (GCMs) run on traditional CPU architectures generally consist of shortwave and longwave parameterizations over a small number of wavelength bands. With the rise of newer GPU and MIC architectures, however, the performance of high resolution line-by-line radiative transfer models may soon approach those of the physical parameterizations currently employed in GCMs. Here we present an analysis of the current performance of a new line-by-line radiative transfer model currently under development at GFDL. Although originally designed to specifically exploit GPU architectures through the use of CUDA, the radiative transfer model has recently been extended to include OpenMP in an effort to also effectively target MIC architectures such as Intel's Xeon Phi. Using input data provided by the upcoming Radiative Forcing Model Intercomparison Project (RFMIP, as part of CMIP 6), we compare model results and performance data for various model configurations and spectral resolutions run on both GPU and Intel Knights Landing architectures to analogous runs of the standard Oxford Reference Forward Model on traditional CPUs.

  16. Ecosystem Considerations for Postdisaster Recovery: Lessons from China, Pakistan, and Elsewhere for Recovery Planning in Haiti

    Directory of Open Access Journals (Sweden)

    Susan A. Mainka

    2011-03-01

    Full Text Available As the world joins forces to support the people of Haiti on their long road of recovery following the January 2010 earthquake, plans and strategies should take into consideration past experiences from other postdisaster recovery efforts with respect to integrating ecosystem considerations. Sound ecosystem management can both support the medium and long-term needs for recovery as well as help to buffer the impacts of future extreme natural events, which for Haiti are likely to include both hurricanes and earthquakes. An additional challenge will be to include the potential impacts of climate change into ecosystem management strategies.

  17. Management and control of microbiologically influenced corrosion (MIC) in the oil and gas industry-Overview and a North Sea case study.

    Science.gov (United States)

    Skovhus, Torben Lund; Eckert, Richard B; Rodrigues, Edgar

    2017-08-20

    Microbiologically influenced corrosion (MIC) is the terminology applied where the actions of microorganisms influence the corrosion process. In literature, terms such as microbial corrosion, biocorrosion, microbially influenced/induced corrosion, and biodegradation are often applied. MIC research in the oil and gas industry has seen a revolution over the past decade, with the introduction of molecular microbiological methods: (MMM) as well as new industry standards and procedures of sampling biofilm and corrosion products from the process system. This review aims to capture the most important trends the oil and gas industry has seen regarding MIC research over the past decade. The paper starts out with an overview of where in the process stream MIC occurs - from the oil reservoir to the consumer. Both biotic and abiotic corrosion mechanisms are explained in the context of managing MIC using a structured corrosion management (CM) approach. The corrosion management approach employs the elements of a management system to ensure that essential corrosion control activities are carried out in an effective, sustainable, well-planned and properly executed manner. The 3-phase corrosion management approach covering of both biotic and abiotic internal corrosion mechanisms consists of 1) corrosion assessment, 2) corrosion mitigation and 3) corrosion monitoring. Each of the three phases are described in detail with links to recent field cases, methods, industry standards and sampling protocols. In order to manage the corrosion threat, operators commonly use models to support decision making. The models use qualitative, semi-quantitative or quantitative measures to help assess the rate of degradation caused by MIC. The paper reviews four existing models for MIC Threat Assessment and describe a new model that links the threat of MIC in the oil processing system located on an offshore platform with a Risk Based Inspection (RBI) approach. A recent field case highlights and explains

  18. DENSE MEDIUM CYCLONE OPTIMIZATON

    Energy Technology Data Exchange (ETDEWEB)

    Gerald H. Luttrell; Chris J. Barbee; Peter J. Bethell; Chris J. Wood

    2005-06-30

    Dense medium cyclones (DMCs) are known to be efficient, high-tonnage devices suitable for upgrading particles in the 50 to 0.5 mm size range. This versatile separator, which uses centrifugal forces to enhance the separation of fine particles that cannot be upgraded in static dense medium separators, can be found in most modern coal plants and in a variety of mineral plants treating iron ore, dolomite, diamonds, potash and lead-zinc ores. Due to the high tonnage, a small increase in DMC efficiency can have a large impact on plant profitability. Unfortunately, the knowledge base required to properly design and operate DMCs has been seriously eroded during the past several decades. In an attempt to correct this problem, a set of engineering tools have been developed to allow producers to improve the efficiency of their DMC circuits. These tools include (1) low-cost density tracers that can be used by plant operators to rapidly assess DMC performance, (2) mathematical process models that can be used to predict the influence of changes in operating and design variables on DMC performance, and (3) an expert advisor system that provides plant operators with a user-friendly interface for evaluating, optimizing and trouble-shooting DMC circuits. The field data required to develop these tools was collected by conducting detailed sampling and evaluation programs at several industrial plant sites. These data were used to demonstrate the technical, economic and environmental benefits that can be realized through the application of these engineering tools.

  19. Refrigeration waste heat recovery

    Energy Technology Data Exchange (ETDEWEB)

    1983-03-01

    UK Super A Stores was built in 1972 and is part of a small indoor shopping complex linked together by a heated mall. The store has a public floor area of approximately 1,232 m{sup 2} (13,261 ft.{sup 2}) and sells the usual variety of food produce including a large selection of frozen foods. There are five lengths of refrigerated display cabinets with a total area of approximately 78 m{sup 2}. There are also some frozen food storage rooms at the back of the store. This report provides a description of a waste heat recovery system within a medium sized food store. It details how the waste heat that is produced by the conventional frozen food display cabinets, can be reused by the store's space heating system. Recommended uses for this waste heat include: diverting to the loading bays which would make the reheat coil unnecessary, diverting to the front of the shop, and heating the adjacent shopping mall. The CREDA (Conservation and Renewable Energy Demonstration Assistance) program contributed $17,444 towards the total project cost of $30,444. The project was initiated by the store owner, who is now realizing a lower annual fuel consumption, with the resulting financial savings. 11 figs., 1 tab.

  20. Rapid Isolation and Susceptibility Testing of Leptospira spp. Using a New Solid Medium, LVW Agar

    Science.gov (United States)

    Wuthiekanun, Vanaporn; Amornchai, Premjit; Paris, Daniel H.; Langla, Sayan; Thaipadunpanit, Janjira; Chierakul, Wirongrong; Smythe, Lee D.; White, Nicholas J.; Day, Nicholas P. J.; Peacock, Sharon J.

    2013-01-01

    Pathogenic Leptospira spp., the causative agents of leptospirosis, are slow-growing Gram-negative spirochetes. Isolation of Leptospira from clinical samples and testing of antimicrobial susceptibility are difficult and time-consuming. Here, we describe the development of a new solid medium that facilitates more-rapid growth of Leptospira spp. and the use of this medium to evaluate the Etest's performance in determining antimicrobial MICs to drugs in common use for leptospirosis. The medium was developed by evaluating the effects of numerous factors on the growth rate of Leptospira interrogans strain NR-20157. These included the type of base agar, the concentration of rabbit serum (RS), and the concentration and duration of CO2 incubation during the initial period of culture. The highest growth rate of NR-20157 was achieved using a Noble agar base supplemented with 10% RS (named LVW agar), with an initial incubation at 30°C in 5% CO2 for 2 days prior to continuous culture in air at 30°C. These conditions were used to develop the Etest for three species, L. interrogans (NR-20161), L. kirschnerii (NR-20327), and L. borgpetersenii (NR-20151). The MICs were read on day 7 for all samples. The Etest was then performed on 109 isolates of pathogenic Leptospira spp. The MIC90 values for penicillin G, doxycycline, cefotaxime, ceftriaxone, and chloramphenicol were 0.64 units/ml and 0.19, 0.047, 0.5, and 2 μg/ml, respectively. The use of LVW agar, which enables rapid growth, isolation of single colonies, and simple antimicrobial susceptibility testing for Leptospira spp., provides an opportunity for new areas of fundamental and applied research. PMID:23114772

  1. Mastite micótica em ruminantes causada por leveduras Mycotic mastitis in ruminants caused by yeasts

    Directory of Open Access Journals (Sweden)

    Andréia Spanamberg

    2009-02-01

    Full Text Available A ocorrência de casos esporádicos de mastite causados por microrganismos de origem ambiental pode ser considerada como emergente e as leveduras, os fungos leveduriformes e os filamentosos são alguns dos principais agentes envolvidos. Em relação à mastite micótica, as leveduras são freqüentemente causas de infecções da glândula mamária em animais produtores de leite. A maior parte dos casos ocorre sob a forma de surtos localizados e/ou após tratamento com antimicrobianos. Os principais gêneros envolvidos são Candida e Cryptococcus, além de outros como Geotrichum, Pichia e Trichosporon. O objetivo do trabalho é revisar os aspectos gerais sobre a mastite micótica causada por leveduras e fungos leveduriformes, tais como etiologia, causas predisponentes, patogenicidade, diagnóstico, tratamento e profilaxia por meio de uma abordagem cronológica dos primeiros relatos, mas com enfoque principal nos resultados descritos recentemente na literatura veterinária nacional e internacional. O controle da mastite micótica é fundamentado em métodos preventivos, como adequado manejo da ordenha, correta higienização dos equipamentos e das instalações, com a finalidade de reduzir o número de animais acometidos, além de garantir a qualidade e a inocuidade dos produtos lácteos.The veterinary literature registers sporadic cases of infections caused by environmental microorganisms in which the main agents involved are yeasts, yeasts-like and filamentous fungi. In relation to dairy animals, the yeasts are more frequently incriminated as the aetiological agents of mycotic mastitis. Most cases occur under the form of localized outbreaks and / or after treatment with antimicrobial agents. The main genera involved in mastitis are Candida and Cryptococcus, besides others such as Geotrichum, Pichia and Trichosporon. The purpose of this review is to point out the main aspects of mastitis caused by yeasts and yeast-like fungi, such as etiology

  2. Elemental and Isotopic Analysis of Uranium Oxide an NIST Glass Standards by FEMTOSECOND-LA-ICP-MIC-MS

    International Nuclear Information System (INIS)

    Ebert, Chris; Zamzow, Daniel S.; McBay, Eddie H.; Bostick, Debra A.; Bajic, Stanley J.; Baldwin, David P.; Houk, R.S.

    2009-01-01

    The objective of this work was to test and demonstrate the analytical figures of merit of a femtosecond-laser ablation (fs-LA) system coupled with an inductively coupled plasma-multi-ion collector-mass spectrometer (ICP-MIC-MS). The mobile fs-LA sampling system was designed and assembled at Ames Laboratory and shipped to Oak Ridge National Laboratory (ORNL), where it was integrated with an ICP-MIC-MS. The test period of the integrated systems was February 2-6, 2009. Spatially-resolved analysis of particulate samples is accomplished by 100-shot laser ablation using a fs-pulsewidth laser and monitoring selected isotopes in the resulting ICP-MS transient signal. The capability of performing high sensitivity, spatially resolved, isotopic analyses with high accuracy and precision and with virtually no sample preparation makes fs-LA-ICP-MIC-MS valuable for the measurement of actinide isotopes at low concentrations in very small samples for nonproliferation purposes. Femtosecond-LA has been shown to generate particles from the sample that are more representative of the bulk composition, thereby minimizing weaknesses encountered in previous work using nanosecond-LA (ns-LA). The improvement of fs- over ns-LA sampling arises from the different mechanisms for transfer of energy into the sample in these two laser pulse-length regimes. The shorter duration fs-LA pulses induce less heating and cause less damage to the sample than the longer ns pulses. This results in better stoichiometric sampling (i.e., a closer correlation between the composition of the ablated particles and that of the original solid sample), which improves accuracy for both intra- and inter-elemental analysis. The primary samples analyzed in this work are (a) solid uranium oxide powdered samples having different 235 U to 238 U concentration ratios, and (b) glass reference materials (NIST 610, 612, 614, and 616). Solid uranium oxide samples containing 235 U in depleted, natural, and enriched abundances were

  3. Uso del EcoMic® y el producto bioactivo Pectimorf® en el establecimiento de dos especies forrajeras Use of EcoMic® and the bioactive product Pectimorf® in the establishment of two forage species

    Directory of Open Access Journals (Sweden)

    Gertrudis Pentón

    2011-09-01

    Full Text Available Con el objetivo de evaluar el efecto de EcoMic®, Pectimorf® y/o su combinación en el establecimiento de las especies forrajeras Morus alba L. (morera y Sorghum bicolor L. (sorgo, se realizaron dos experimentos. El primero se hizo con M. alba, inoculada o no con HMA, y se evaluaron las variables del rendimiento y la supervivencia de las plantas a los 90 y 240 días. El experimento con S. bicolor se realizó durante 30 días a partir de la siembra, y se evaluó la germinación de las semillas y las variables del rendimiento a los 7, 15 y 30 días. Los tratamientos fueron: testigo, inoculación con HMA, imbibición en Pectimorf, y su combinación. Se empleó un diseño en bloques al azar, con tres repeticiones. Se obtuvo respuesta de la morera a la inoculación con HMA a los 90 días de establecimiento, en términos de peso verde de las raicillas y las raíces, que triplicaron los resultados del testigo. A los 240 días las plantas inoculadas duplicaron el rendimiento del testigo y no hubo diferencias significativas en la supervivencia, en el incremento de biomasa comestible por unidad de área foliar, ni en la relación del sistema asimilativo por unidad de biomasa comestible. En el sorgo, el empleo combinado del Pectimorf® y el EcoMic® produjo un aumento significativo, respecto al testigo, en la germinación de las semillas a los 30 días (89 vs 58%, la altura efectiva (4,04 vs 3,55 cm, el grosor de la base del tallo (0,18 vs 0,15 cm, el área del limbo, el número de hojas abiertas (4 vs 3 y el largo de las hojas. Se concluye que los productos EcoMic® y Pectimorf®, así como su combinación constituyen una alternativa efectiva para el establecimiento de las especies forrajeras estudiadas.In order to evaluate the effect of EcoMic®, Pectimorf® and/or their combination on the establishment of the forage species Morus alba L. (mulberry and Sorghum bicolor L. (sorghum, two trials were conducted. The first one was done with M. alba

  4. Computation as Medium

    DEFF Research Database (Denmark)

    Jochum, Elizabeth Ann; Putnam, Lance

    2017-01-01

    Artists increasingly utilize computational tools to generate art works. Computational approaches to art making open up new ways of thinking about agency in interactive art because they invite participation and allow for unpredictable outcomes. Computational art is closely linked...... to the participatory turn in visual art, wherein spectators physically participate in visual art works. Unlike purely physical methods of interaction, computer assisted interactivity affords artists and spectators more nuanced control of artistic outcomes. Interactive art brings together human bodies, computer code......, and nonliving objects to create emergent art works. Computation is more than just a tool for artists, it is a medium for investigating new aesthetic possibilities for choreography and composition. We illustrate this potential through two artistic projects: an improvisational dance performance between a human...

  5. Spiegel. Medium. Kunst

    DEFF Research Database (Denmark)

    Kacunko, Slavko

    of this kind as the marks of a meta-complex of method out of which new models of the image continually arise. The waxing intangibility of proliferating images be they of the mind, in dreams, through gestures, and the equally rampant growth of microstructuring in allocations of knowledge lay a challenge before...... to research. As a void in the apprehension of the world, the mirror obtained a scholarly perspective and the more so in areas beyond its own qualities as a medium, i.e. in images and metaphor, the paradigms of all research looking to image and text. This investigation sets out to comprehend paradoxes......, and space (albeit no expanse) is there to consider the methodological pros and cons of such a selective approach. Even in this synopsis, it has to be and can be stated that what makes for the affinities between psychological, literary and image-research approaches in research on the mirror is the shared...

  6. The diffuse interstellar medium

    Science.gov (United States)

    Cox, Donald P.

    1990-01-01

    The last 20 years of the efforts to understand the diffuse ISM are reviewed, with recent changes of fundamental aspects being highlighted. Attention is given to the interstellar pressure and its components, the weight of the ISM, the midplane pressure contributions, and pressure contributions at 1 kpc. What velocity dispersions, cosmic ray pressure, and magnetic field pressure that can be expected for a gas in a high magnetic field environment is addressed. The intercloud medium is described, with reference to the work of Cox and Slavin (1989). Various caveats are discussed and a number of areas for future investigation are identified. Steps that could be taken toward a successful phase segregation model are discussed.

  7. Plasma MIC-1 correlates with systemic inflammation but is not an independent determinant of nutritional status or survival in oesophago-gastric cancer.

    Science.gov (United States)

    Skipworth, R J E; Deans, D A C; Tan, B H L; Sangster, K; Paterson-Brown, S; Brown, D A; Hunter, M; Breit, S N; Ross, J A; Fearon, K C H

    2010-02-16

    Macrophage inhibitory cytokine-1(MIC-1) is a potential modulator of systemic inflammation and nutritional depletion, both of which are adverse prognostic factors in oesophago-gastric cancer (OGC). Plasma MIC-1, systemic inflammation (defined as plasma C-reactive protein (CRP) of > or =10 mg l(-1) or modified Glasgow prognostic score (mGPS) of > or =1), and nutritional status were assessed in newly diagnosed OGC patients (n=293). Healthy volunteers (n=35) served as controls. MIC-1 was elevated in patients (median=1371 pg ml(-1); range 141-39 053) when compared with controls (median=377 pg ml(-1); range 141-3786; Pgastric tumours (median=1592 pg ml(-1); range 141-12 643) showed higher MIC-1 concentrations than patients with junctional (median=1337 pg ml(-1); range 383-39 053) and oesophageal tumours (median=1180 pg ml(-1); range 258-31 184; P=0.015). Patients showed a median weight loss of 6.4% (range 0.0-33.4%), and 42% of patients had an mGPS of > or =1 or plasma CRP of > or =10 mg l(-1) (median=9 mg l(-1); range 1-200). MIC-1 correlated positively with disease stage (r(2)=0.217; Pnutritional status or survival in OGC.

  8. Evaluation of protective effect of multiantigenic DNA vaccine encoding MIC3 and ROP18 antigen segments of Toxoplasma gondii in mice.

    Science.gov (United States)

    Qu, Daofeng; Han, Jianzhong; Du, Aifang

    2013-07-01

    The high incidence and severe damage caused by Toxoplasma gondii infection clearly indicates the need for the development of a vaccine. In this study, we evaluated the immune responses and protection against toxoplasmosis by immunizing ICR mice with a multiantigenic DNA vaccine. To develop the multiantigenic vaccine, two T. gondii antigens, MIC3 and ROP18, selected on the basis of previous studies were chosen. ICR mice were immunized subcutaneously with PBS, empty pcDNA3.1 vector, pMIC3, pROP18, and pROP18-MIC3, respectively. The results of lymphocyte proliferation assay, cytokine, and antibody determinations showed that mice immunized with pROP18-MIC3 elicited stronger humoral and Th1-type cellular immune responses than those immunized with single-gene plasmids, empty plasmid, or phosphate-buffered saline. After a lethal challenge with the highly virulent T. gondii RH strain, a prolonged survival time in pROP18-MIC3-immunized mice was observed in comparison to control groups. Our study indicates that the introduction of multiantigenic DNA vaccine is more powerful and efficient than single-gene vaccine, and deserves further evaluation and development.

  9. Are Vancomycin Trough Concentrations of 15 to 20 mg/L Associated With Increased Attainment of an AUC/MIC ≥ 400 in Patients With Presumed MRSA Infection?

    Science.gov (United States)

    Hale, Cory M; Seabury, Robert W; Steele, Jeffrey M; Darko, William; Miller, Christopher D

    2017-06-01

    To determine whether there is an association between higher vancomycin trough concentrations and attainment of a calculated area under the concentration-time curve (AUC)/minimum inhibitory concentration (MIC) ≥400. A retrospective analysis was conducted among vancomycin-treated adult patients with a positive methicillin-resistant Staphylococcus aureus (MRSA) culture. Attainment of a calculated AUC/MIC ≥400 was compared between patients with troughs in the reference range of 15 to 20 mg/L and those with troughs in the following ranges: 20 mg/L. Nephrotoxicity was assessed as a secondary outcome based on corrected average vancomycin troughs over 10 days of treatment. Overall, 226 patients were reviewed and 100 included. Relative to troughs ≥10, patients with vancomycin troughs AUC/MIC ≥400 (odds ratio [OR] 0.27, 95% confidence interval [CI]: 0.01-0.75). No difference was found in the attainment of an AUC/MIC ≥400 in patients with troughs of 10 to 14.9 mg/L and >20 mg/L when compared to patients with troughs of 15 to 20 mg/L. The mean corrected average vancomycin trough was higher in patients developing nephrotoxicity compared to those who did not (19.5 vs 14.5 mg/L, P AUC/MIC target relative to troughs of 10 to 14.9 mg/L but may increase nephrotoxicity risk.

  10. Postantibiotic effects and postantibiotic sub-MIC effects of tilmicosin, erythromycin and tiamulin on erythromycin-resistant Streptococcus suis

    Directory of Open Access Journals (Sweden)

    Liping Wang

    2009-12-01

    Full Text Available The postantibiotic effects (PAEs and postantibiotic sub-MIC effects (PA SMEs of tilmicosin, erythromycin and tiamulin on erythromycin-susceptible and erythromycin-resistant strains of Streptococcus suis (M phenotype were investigated in vitro. Tilmicosin and tiamulin induced significantly longer PAE and PA SME against both erythromycin-susceptible and erythromycin-resistant strains than did erythromycin. The durations of PAE and PA SMEs were proportional to the concentrations of drugs used for exposure. The PA SMEs were substantially longer than PAEs on S. suis (P<0.05 regardless of the antimicrobial used for exposure. The results indicated that the PAE and PA SME could help in the design of efficient control strategies for infection especially caused by erythromycin-resistant S. suis and that they may provide additional valuable information for the rational drug use in clinical practice.

  11. Postantibiotic effects and postantibiotic sub-MIC effects of tilmicosin, erythromycin and tiamulin on erythromycin-resistant Streptococcus suis.

    Science.gov (United States)

    Wang, Liping; Zhang, Yuanshu

    2009-10-01

    The postantibiotic effects (PAEs) and postantibiotic sub-MIC effects (PA SMEs) of tilmicosin, erythromycin and tiamulin on erythromycin-susceptible and erythromycin-resistant strains of Streptococcus suis (M phenotype) were investigated in vitro. Tilmicosin and tiamulin induced significantly longer PAE and PA SME against both erythromycin-susceptible and erythromycin-resistant strains than did erythromycin. The durations of PAE and PA SMEs were proportional to the concentrations of drugs used for exposure. The PA SMEs were substantially longer than PAEs on S. suis (P<0.05) regardless of the antimicrobial used for exposure. The results indicated that the PAE and PA SME could help in the design of efficient control strategies for infection especially caused by erythromycin-resistant S. suis and that they may provide additional valuable information for the rational drug use in clinical practice.

  12. Mathematical model for the growth of P. aeruginosa and four mutator strains in sub-MIC concentration of Ciprofloxacin

    DEFF Research Database (Denmark)

    Philipsen, Kirsten Riber; Christiansen, Lasse Engbo; Madsen, Henrik

    growing under sub-MIC Ciprofloxacin concentration (0.1 μg/ml), in order to describe the growth pattern under the presence of antibiotic. Data available for the modelling process is bioscreen measurements of the bacterial content as a function of time for each bacteria strain growing in LB media...... is that the presence of antibiotic results in selection of mutators in the lungs of CF patients, as these bacteria has a higher fitness under the presence of antibiotics. The goal of this study is to model the growth of P. aeruginosa and four different mutator strains (PAO1 mutT, mutY, mutM and mutM-mutY mutants) when......P. aeruginosa causes very critical and complicated infections, for which treatment is strongly dependent on successful antibiotic treatment. Therefore the evolution of antibiotic resistant P. aeruginosa does have serious consequences. Cystic fibrosis (CF) is characterized by the chronic P...

  13. Accuracy of the Thermo Fisher Scientific (Sensititre™) dry-form broth microdilution MIC product when testing ceftaroline.

    Science.gov (United States)

    Jones, Ronald N; Holliday, Nicole M; Critchley, Ian A

    2015-04-01

    Ceftaroline, the active metabolite of the ceftaroline fosamil pro-drug, was the first advanced-spectrum cephalosporin with potent activity against methicillin-resistant Staphylococcus aureus to be approved by the US Food and Drug Administration for acute bacterial skin and skin structure infections. After 4 years of clinical use, few ceftaroline commercial susceptibility testing devices other than agar diffusion methods (disks and stable gradient) are available. Here, we validate a broth microdilution product (Sensititre™; Thermo Fisher Scientific, Cleveland, OH, USA) that achieved 99.2% essential agreement (manual and automated reading) and 95.3-100.0% categorical agreement, with high reproducibility (98.0-100.0%). Sensititre™ MIC values for ceftaroline, however, were slightly skewed toward an elevated value (0.5 × log2 dilution step), greatest when testing for streptococci and Enterobacteriaceae. Copyright © 2015 Elsevier Inc. All rights reserved.

  14. Performance of a 100V Half-Bridge MOSFET Driver, Type MIC4103, Over a Wide Temperature Range

    Science.gov (United States)

    Patterson, Richard L.; Hammoud, Ahmad

    2011-01-01

    The operation of a high frequency, high voltage MOSFET (metal-oxide semiconductor field-effect transistors) driver was investigated over a wide temperature regime that extended beyond its specified range. The Micrel MIC4103 is a 100V, non-inverting, dual driver that is designed to independently drive both high-side and low-side N-channel MOSFETs. It features fast propagation delay times and can drive 1000 pF load with 10ns rise times and 6 ns fall times [1]. The device consumes very little power, has supply under-voltage protection, and is rated for a -40 C to +125 C junction temperature range. The floating high-side driver of the chip can sustain boost voltages up to 100 V. Table I shows some of the device manufacturer s specification.

  15. Performance of a radio link between a base station and a medical implant utilising the MICS standard.

    Science.gov (United States)

    Johansson, Anders J

    2004-01-01

    Modern medical implants are of increasing complexity and with that, the need for fast and flexible communication with them grows. A wireless system is preferable and an inductive link is the most commonly used. But it has the drawback of a very short range, essentially limited to having the external transceiver touching the patient. The Medical Implant Communication System, MICS, is a standard aimed at improving the communication distance. It operates at a higher frequency band between 402 MHz and 405 MHz. We have by simulations and measurements investigated the channel properties of this band and calculated the link performance for a typical implant application. The result is a link speed between a base station and a bedridden patient of 600 kbit bits per second with a bit error rate of 2% in the downlink to the implant and 1 % in the uplink to the base station. Conclusions on the necessary complexity of the base station are also given.

  16. La rentabilidad del cómic en la enseñanza de la cultura en E/LE

    Directory of Open Access Journals (Sweden)

    Jaume Brines Gandía

    2012-08-01

    Full Text Available El presente trabajo trata sobre el uso del cómic como recurso didáctico en la clase de E/LE para enseñar cultura. Aunque la cultura en la clase de E/LE muchas veces pasa desapercibida, constituye un excelente instrumento para la enseñanza de la lengua extranjera y, sobre todo, para que el futuro aprendiente sepa cómo, cuándo y de qué modo usar la lengua. Antes de desarrollar la presente experiencia práctica, es necesario que tratemos el término cultura y las distintas acepciones que supone.

  17. La rentabilidad del cómic en la enseñanza de la cultura en E/LE

    Directory of Open Access Journals (Sweden)

    Jaume Brines Gandía

    2012-01-01

    Full Text Available El presente trabajo trata sobre el uso del cómic como recurso didáctico en la clase de E/LE para enseñar cultura. Aunque la cultura en la clase de E/LE muchas veces pasa desapercibida, constituye un excelente instrumento para la enseñanza de la lengua extranjera y, sobre todo, para que el futuro aprendiente sepa cómo, cuándo y de qué modo usar la lengua. Antes de desarrollar la presente experiencia práctica, es necesario que tratemos el término cultura y las distintas acepciones que supone.

  18. Energy-Efficient and Comfortable Buildings through Multivariate Integrated Control (ECoMIC)

    Energy Technology Data Exchange (ETDEWEB)

    Birru, Dagnachew [Philips Electronics North America Corporation, Andover, MA (United States); Wen, Yao-Jung [Philips Electronics North America Corporation, Andover, MA (United States); Rubinstein, Francis M. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Clear, Robert D. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2013-10-28

    developed control technology were evaluated and verified through both simulations and testbed implementations. Simulations coupling a DOE medium office reference building in EnergyPlus building simulation software and a prototype controller in Matlab were performed. During summer time in a mixed-humid climate zone, the simulations revealed reductions of 27% and 42% in electric lighting load and cooling load, respectively, when compared to an advanced base case with daylight dimming and blinds automatically tilted to block direct sun. Two single-room testbeds were established. The testbed at Philips Lighting business building (Rosemont, IL) was designed for quantifying energy performance of integrated controls. This particular implementation achieved 40% and 79% savings on lighting and HVAC energy, respectively, compared to a relatively simple base case operated on predefined schedules. While the resulting energy savings was very encouraging, it should be noted that there may be several caveats associated with it. 1) The test was run during late spring and early summer, and the savings numbers might not be directly used to extrapolate the annual energy savings. 2) Due to the needs for separate control and metering of the small-scale demonstrator within a large building, the HVAC system, hence the corresponding savings, did not represent a typical energy code-compliant design. 3) The light level in the control case was regulated at a particular setpoint, which was lower than then the full-on light level in the base case, and the savings resulted from tuning down the light level to the setpoint was not attributable to the contribution of the developed technology. The testbed at the Lawrence Berkeley National Laboratory (Berkeley, CA) specifically focused on glare control integration, and has demonstrated the feasibility and capability of the glare detection and prevention technique. While the short one-month test in this testbed provided a functional indication of the

  19. CONSIDERAȚII TEORETICO-METODOLOGICE PRIVIND DESFĂȘURAREA AUTOEDUCAȚIEI ȘCOLARULUI MIC

    Directory of Open Access Journals (Sweden)

    Natalia POPA

    2017-07-01

    Full Text Available Analiza literaturii de specialitate, observațiile noastre, rezultatele chestionării și ale conversației cu cadrele didactice demonstrează posibilitățile realizării unei auto/educații de calitate și necesitatea depunerii unui efort intelectual și moral-volitiv atât din partea elevilor, cât și a părinților și pedagogilor în direcția autoinstruirii, autoeducației și învățării pe parcursul vieții. În acest sens a fost elaborată matricea achizițiilor principale ale școlarului mic, care orientează adulții în direcția strategiilor ce pot fi aplicate în stimularea autoeducației școlarului mic.THEORETICAL AND METHODOLOGICAL CONSIDERATIONS ON UNFOLDING PRIMARY SCHOOL CHILDREN SELF-EDUCATIONThe literature analysis, our observations, results of questioning and conversation with teachers demonstrate the possibilities of achieving quality self/education and the need to make an intellectual and moral-volitional effort, both from students, parents and teachers towards self-training, self-education and lifelong learning. In this respect, the matrix of main achievements of small pupil, guiding adults towards strategies that can be applied to stimulate self-education primary school children has been developed.

  20. Recovery from schizophrenia and the recovery model.

    Science.gov (United States)

    Warner, Richard

    2009-07-01

    The recovery model refers to subjective experiences of optimism, empowerment and interpersonal support, and to a focus on collaborative treatment approaches, finding productive roles for user/consumers, peer support and reducing stigma. The model is influencing service development around the world. This review will assess whether optimism about outcome from serious mental illness and other tenets of the recovery model are borne out by recent research. Remission of symptoms has been precisely defined, but the definition of 'recovery' is a more diffuse concept that includes such factors as being productive and functioning independently. Recent research and a large, earlier body of data suggest that optimism about outcome from schizophrenia is justified. A substantial proportion of people with the illness will recover completely and many more will regain good social functioning. Outcome is better for people in the developing world. Mortality for people with schizophrenia is increasing but is lower in the developing world. Working appears to help people recover from schizophrenia, and recent advances in vocational rehabilitation have been shown to be effective in countries with differing economies and labor markets. A growing body of research supports the concept that empowerment is an important component of the recovery process. Key tenets of the recovery model - optimism about recovery from schizophrenia, the importance of access to employment and the value of empowerment of user/consumers in the recovery process - are supported by the scientific research. Attempts to reduce the internalized stigma of mental illness should enhance the recovery process.

  1. Nuevos lenguajes para nuevas tecnologías. El cómic, una publicación electrónica de entretenimiento

    Directory of Open Access Journals (Sweden)

    Lic. Virginia Luzón Fernández

    1999-01-01

    Full Text Available Hasta hoy día el cómic ha sido concebido como un medio narrativo de comunicación social que comprende gráficos y textos con un desarrollo secuencial y una narrativa interna. Ha estado relacionado con unos códigos particulares y una serie de convenciones expresivas, como los globos. Pero, el cómic de papel que leíamos, coleccionábamos e incluso algunos veneraban, está dejando paso a un nuevo tipo de cómic que nace con el desarrollo de las nuevas tecnologías y encaja a la perfección en la que denominamos, no sólo sociedad de la información, sino también nueva sociedad de la velocidad.

  2. Heart Attack Recovery FAQs

    Science.gov (United States)

    ... recommendations to make a full recovery. View an animation of a heart attack . Heart Attack Recovery Questions ... Support Network Popular Articles 1 Understanding Blood Pressure Readings 2 Sodium and Salt 3 Heart Attack Symptoms ...

  3. Water Recovery Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The AES Water Recovery Project (WRP) is advancing environmental control and life support systems water recovery technologies to support human exploration beyond low...

  4. EPA Recovery Mapper

    Data.gov (United States)

    U.S. Environmental Protection Agency — The EPA Recovery Mapper is an Internet interactive mapping application that allows users to discover information about every American Recovery and Reinvestment Act...

  5. E. coli encoding blaNDM-5 associated with community-acquired UTI cases with unusual MIC creep like phenomenon against Imipenem.

    Science.gov (United States)

    Gajamer, Varsha Rani; Bhattacharjee, Amitabha; Paul, Deepjyoti; Deshamukhya, Chandrayee; Singh, Ashish Kr; Pradhan, Nilu; Tiwari, Hare Krishna

    2018-05-15

    Carbapenemase-producing Escherichia coli are of major clinical concern. The present study aimed to identify NDM-5 producing E.coli associated with community-acquired urinary tract infection, co-harboring ESBL genes and a pattern of imipenem MIC creep. A total of 973 urine samples were collected from females of age between 18-49 diagnosed with UTI. Isolates were identified by standard microbiological procedures. Presence of bla NDM and ESBL genes was determined by PCR assay and sequencing.PCR based replicon typing was performed. Plasmid stability of all bla producers and their transformants study were analyzed by serial passages and MIC creep phenomenon was analysed by studying revertants. Among 34 bla NDM-5 positive E.coli isolates, 21 isolates co harbored bla CTX-M-15 , followed by multiple combinations of genes. The study revealed diverse types of plasmids type viz; HI1, I1, FIA+FIB, FIA and Y. The strains showed progressive plasmid loss after 31 passages.Twenty-eight isolates mostly had MIC value of 0.5μg/ml and 1μg/ml against imipenem, ertapenem and meropenem. However, on studying the MIC creep activity; the MIC was found elevated from 0.5ug/ml to 64μg/ml and from 1μg/ml to 128μg/ml. While analyzing the revertants, MIC of most of the NDM positive isolates was reduced to 16μg/ml after the 30th serial passages. This study observed a unique phenotype of NDM producers which is not been reported earlier. In the current study, the observed phenomenon poses a global threat as these pathogens may evade phenotypic screening by routine laboratories. Copyright © 2018. Published by Elsevier Ltd.

  6. mic como instrumento didáctico. La narración gráfica en ámbito universitario

    OpenAIRE

    Baile López, Eduard; Maestre-Brotons, Antoni; Ortiz Hernández, Francisco Javier; Rovira-Collado, José; Pomares Puig, María Pilar; Soler-Quílez, Guillermo; Villaverde Pérez, Abel; Bernabé Gallardo, Carlos; Rovira Collado, Joan Miquel; Sánchez Verdú, Ramón; Serna-Rodrigo, Rocío; Vidal Martín-Toledano, Jesús

    2016-01-01

    Mediante la red 3489, se ha pretendido dar, tal como ya se hizo en la convocatòria anterior de Redes de la UA, presencia académica a la labor de estudio y difusión sobre las posibilidades didácticas del cómic que se viene desarrollando desde los núcleos de Unicómic y CLUECA. En este sentido, la memoria pretende ser testimonio del trabajo investigador y docente llevado a cabo por los diversos miembros en el curso académico 2015-2016. A nuestro juicio, hacer recuento del camino recorrido es con...

  7. Evaluation of MIC Strip Isavuconazole test for susceptibility testing of wild-type and non-wild-type Aspergillus fumigatus isolates

    DEFF Research Database (Denmark)

    Arendrup, Maiken Cavling; Verweij, Paul; Nielsen, Henrik Vedel

    2017-01-01

    We evaluated the MIC Strip Isavuconazole test against EUCAST E.Def 9.3 by using 40 wild-type and 39 CYP51A mutant Aspergillus fumigatus strains. The strip full inhibition endpoint (FIE) and 80% growth inhibition endpoint were determined by two independent readers, reader 1 (R1) and R2. The essent......We evaluated the MIC Strip Isavuconazole test against EUCAST E.Def 9.3 by using 40 wild-type and 39 CYP51A mutant Aspergillus fumigatus strains. The strip full inhibition endpoint (FIE) and 80% growth inhibition endpoint were determined by two independent readers, reader 1 (R1) and R2...

  8. Recovery from mental illness

    DEFF Research Database (Denmark)

    Petersen, Kirsten Schultz; Friis, Vivi Soegaard; Haxholm, Birthe Lodahl

    2015-01-01

    Mental health services strive to implement a recovery-oriented approach to rehabilitation. Little is known about service users' perception of the recovery approach. The aim is to explore the service user's perspectives on facilitators and barriers associated with recovery. Twelve residents living...

  9. Improving sample recovery

    International Nuclear Information System (INIS)

    Blanchard, R.J.

    1995-09-01

    This Engineering Task Plan (ETP) describes the tasks, i.e., tests, studies, external support and modifications planned to increase the recovery of the recovery of the waste tank contents using combinations of improved techniques, equipment, knowledge, experience and testing to better the recovery rates presently being experienced

  10. Development of novel Alicyclobacillus spp. isolation medium.

    Science.gov (United States)

    Chang, S; Kang, D-H

    2005-01-01

    To develop a new isolation medium with higher recovery rates of Alicyclobacillus spp. SK agar was developed with optimized incubation temperature, pH, acidulant, Tween 80 concentration and divalent cation addition. Results indicate that detection of Alicyclobacillus spp. by SK agar was significantly higher (P > 0.05) than those obtained by K agar, orange serum agar, and potato dextrose agar. Current media used for Alicyclobacillus spp. isolation still resulted in high numbers of false negative products. The sensitivity of SK agar to Alicyclobacillus spp. allows detection of low numbers of Alicyclobacillus spp. and also provides a more higher isolation results compared with currently used media. SK agar will be useful to the fruit juice industry to obtain more accurate numbers of contaminant Alicyclobacillus spp. With this media, false negative samples can be reduced, and the likelihood of exported products being rejected can be greatly reduced.

  11. Predicting functional recovery after acute ankle sprain.

    Directory of Open Access Journals (Sweden)

    Sean R O'Connor

    Full Text Available Ankle sprains are among the most common acute musculoskeletal conditions presenting to primary care. Their clinical course is variable but there are limited recommendations on prognostic factors. Our primary aim was to identify clinical predictors of short and medium term functional recovery after ankle sprain.A secondary analysis of data from adult participants (N = 85 with an acute ankle sprain, enrolled in a randomized controlled trial was undertaken. The predictive value of variables (age, BMI, gender, injury mechanism, previous injury, weight-bearing status, medial joint line pain, pain during weight-bearing dorsiflexion and lateral hop test recorded at baseline and at 4 weeks post injury were investigated for their prognostic ability. Recovery was determined from measures of subjective ankle function at short (4 weeks and medium term (4 months follow ups. Multivariate stepwise linear regression analyses were undertaken to evaluate the association between the aforementioned variables and functional recovery.Greater age, greater injury grade and weight-bearing status at baseline were associated with lower function at 4 weeks post injury (p<0.01; adjusted R square=0.34. Greater age, weight-bearing status at baseline and non-inversion injury mechanisms were associated with lower function at 4 months (p<0.01; adjusted R square=0.20. Pain on medial palpation and pain on dorsiflexion at 4 weeks were the most valuable prognostic indicators of function at 4 months (p< 0.01; adjusted R square=0.49.The results of the present study provide further evidence that ankle sprains have a variable clinical course. Age, injury grade, mechanism and weight-bearing status at baseline provide some prognostic information for short and medium term recovery. Clinical assessment variables at 4 weeks were the strongest predictors of recovery, explaining 50% of the variance in ankle function at 4 months. Further prospective research is required to highlight the factors

  12. Battleground Energy Recovery Project

    Energy Technology Data Exchange (ETDEWEB)

    Bullock, Daniel [USDOE Gulf Coast Clean Energy Application Center, Woodlands, TX (United States)

    2011-12-31

    In October 2009, the project partners began a 36-month effort to develop an innovative, commercial-scale demonstration project incorporating state-of-the-art waste heat recovery technology at Clean Harbors, Inc., a large hazardous waste incinerator site located in Deer Park, Texas. With financial support provided by the U.S. Department of Energy, the Battleground Energy Recovery Project was launched to advance waste heat recovery solutions into the hazardous waste incineration market, an area that has seen little adoption of heat recovery in the United States. The goal of the project was to accelerate the use of energy-efficient, waste heat recovery technology as an alternative means to produce steam for industrial processes. The project had three main engineering and business objectives: Prove Feasibility of Waste Heat Recovery Technology at a Hazardous Waste Incinerator Complex; Provide Low-cost Steam to a Major Polypropylene Plant Using Waste Heat; and Create a Showcase Waste Heat Recovery Demonstration Project.

  13. Mesons in the nuclear Medium

    CERN Document Server

    Kotulla, M

    2006-01-01

    We discuss recent experimental results on the modification of hadron properties in a nuclear medium. Particular emphasis is placed on an $\\omega$ production experiment performed by the CBELSA/TAPS collaboration at the ELSA accelerator. The data shows a smaller $\\omega$ meson mass together with a significant increase of its width in the nuclear medium.

  14. [Evaluation of the methodological quality of the Rémic (microbiology guidelines - bacteriology and mycology) of the Société française de microbiologie].

    Science.gov (United States)

    Fonfrède, Michèle; Couaillac, Jean Paul; Augereau, Christine; De Moüy, Danny; Lepargneur, Jean Pierre; Szymanowicz, Anton; Watine, Joseph

    2011-01-01

    We have evaluated the methodological quality of the Rémic (microbiology guidelines - bacteriology and mycology) of the Société française de microbiologie (edition2007), using to AGREE criteria, which are consensual at an international level, in particular at the the World Health Organisation (WHO) and at the European Union. The methodological quality of the Rémic appears to be sub-optimal. These shortcomings in quality are mainly observed in AGREE domain n° 5 (applicability), in AGREE item n° 5 (patients' opinions were not considered), and in AGREE item n° 23 (conflicts of interest were not declared). The users of the Rémic must be aware of these few methodological shortcomings in order for them to be careful before they put its recommendation in practice. In conclusion, we advise the editors of the Rémic to insert at least a methodological chapter in their next edition.

  15. National and gender measurement invariance of the Utrecht-Management of Identity Commitments Scale (U-MICS) : A 10-nation study with university students

    NARCIS (Netherlands)

    Crocetti, E.; Cieciuch, J.; Gao, C.-H.; Klimstra, T.A.; Lin, C.-L.; Mena de Matos, P.; Morsünbül, U.; Negru, O.; Sugimura, K.; Zimmermann, G.; Meeus, W.H.J.

    2015-01-01

    The purpose of this study was to examine the psychometric properties of the Utrecht-Management of Identity Commitments Scale (U-MICS), a self-report measure aimed at assessing identity processes of commitment, in-depth exploration, and reconsideration of commitment. We tested its factor structure in

  16. National and Gender Measurement Invariance of the Utrecht-Management of Identity Commitments Scale (U-MICS) : A 10-Nation Study With University Students

    NARCIS (Netherlands)

    Crocetti, Elisabetta; Cieciuch, Jan; Gao, Cheng Hai; Klimstra, Theo; Lin, Ching Ling; Matos, Paula Mena; Morsünbül, Ümit; Negru, Oana; Sugimura, Kazumi; Zimmermann, Grégoire; Meeus, Wim

    2015-01-01

    The purpose of this study was to examine the psychometric properties of the Utrecht-Management of Identity Commitments Scale (U-MICS), a self-report measure aimed at assessing identity processes of commitment, in-depth exploration, and reconsideration of commitment. We tested its factor structure in

  17. Brief report: The Utrecht-Management of Identity Commitments Scale (U-MICS): Gender and age measurement invariance and convergent validity of the Turkish version

    NARCIS (Netherlands)

    Morsunbul, Umit; Crocetti, Elisabetta; Cok, Figen; Meeus, Wim

    2014-01-01

    The purpose of this study was to evaluate the factor structure and convergent validity of the Turkish version of the Utrecht-Management of Identity Commitments Scale (U-MICS). Participants were 1201 (59.6% females) youth aged between 12 and 24 years (Mage=17.53 years, SDage=3.25). Results indicated

  18. Brief report: The Utrecht-Management of Identity Commitments Scale (U-MICS) : Gender and age measurement invariance and convergent validity of the Turkish version

    NARCIS (Netherlands)

    Morsunbul, Umit; Crocetti, Elisabetta; Cok, Figen; Meeus, W.H.J.

    2014-01-01

    The purpose of this study was to evaluate the factor structure and convergent validity of the Turkish version of the Utrecht-Management of Identity Commitments Scale (U-MICS). Participants were 1201 (59.6% females) youth aged between 12 and 24 years (Mage = 17.53 years, SDage = 3.25). Results

  19. Rhodium, iridium and nickel complexes with a 1,3,5-triphenylbenzene tris-MIC ligand. Study of the electronic properties and catalytic activities

    Directory of Open Access Journals (Sweden)

    Carmen Mejuto

    2015-12-01

    Full Text Available The coordination versatility of a 1,3,5-triphenylbenzene-tris-mesoionic carbene ligand is illustrated by the preparation of complexes with three different metals: rhodium, iridium and nickel. The rhodium and iridium complexes contained the [MCl(COD] fragments, while the nickel compound contained [NiCpCl]. The preparation of the tris-MIC (MIC = mesoionic carbene complex with three [IrCl(CO2] fragments, allowed the estimation of the Tolman electronic parameter (TEP for the ligand, which was compared with the TEP value for a related 1,3,5-triphenylbenzene-tris-NHC ligand. The electronic properties of the tris-MIC ligand were studied by cyclic voltammetry measurements. In all cases, the tris-MIC ligand showed a stronger electron-donating character than the corresponding NHC-based ligands. The catalytic activity of the tri-rhodium complex was tested in the addition reaction of arylboronic acids to α,β-unsaturated ketones.

  20. AUC/MIC Pharmacodynamic Target Is Not a Good Predictor of Vancomycin Efficacy in Methicillin-Resistant Staphylococcus aureus Experimental Endocarditis.

    Science.gov (United States)

    Castañeda, Ximena; García-de-la-Mària, Cristina; Gasch, Oriol; Pericas, Juan M; Armero, Yolanda; Soy, Dolors; García-González, Javier; Falces, Carlos; Ninot, Salvador; Almela, Manel; Ambrosioni, Juan; Quintana, Eduardo; Vidal, Barbara; Fuster, David; Llopis, Jaume; Soto, Sara; Moreno, Asuncion; Marco, Francesc; Miró, Jose M

    2017-06-01

    The aim of this in vivo study was to compare the efficacy of vancomycin at standard doses (VAN-SD) to that of VAN at adjusted doses (VAN-AD) in achieving a VAN area under the curve/MIC ratio (AUC/MIC) of ≥400 against three methicillin-resistant Staphylococcus aureus (MRSA) strains with different microdilution VAN MICs in an experimental endocarditis model. The valve vegetation bacterial counts after 48 h of VAN therapy were compared, and no differences were observed between the two treatment groups for any of the three strains tested. Overall, for VAN-SD and VAN-AD, the rates of sterile vegetations were 15/45 (33.3%) and 21/49 (42.8%) ( P = 0.343), while the medians (interquartile ranges [IQRs]) for log 10 CFU/g of vegetation were 2 (0 to 6.9) and 2 (0 to 4.5) ( P = 0.384), respectively. In conclusion, this VAN AUC/MIC pharmacodynamic target was not a good predictor of vancomycin efficacy in MRSA experimental endocarditis. Copyright © 2017 American Society for Microbiology.

  1. Luces y sombras de la amazona de cómic Wonder Woman, la mujer maravilla = Lights and shadows of the comic Wonderwoman

    Directory of Open Access Journals (Sweden)

    M.ª Inmaculada Concepción Marfil Díaz

    2015-06-01

    Full Text Available La mujer constituye una parte determinante que sustenta el tejido social de todas las culturas y, sin embargo, no ha sido protagonista principal en el mundo del cómic de superhéroes. Pero hay excepciones, como Wonder Woman, la Mujer Maravilla. ¿Qué sucede con este personaje que forma trinidad con Batman y Superman sin apenas resonancia en el universo del cómic? ¿Qué relación existe entre el mito y el cómic? ¿Quién crea esta superheroina? Este trabajo es una aproximación al mito de las amazonas junto a la evolución de este personaje de cómic norteamericano.Even though women are crucial to the sustainability of the social fabric in every culture, they have not been the main protagonists in the world of Comic Superheroes. There are, of course, exceptions such as Wonder Woman but, who is this character that, in spite of forming a trinity with Batman and Superman, has hardly had any relevance in the universe of Comics? What is the relationship between the myth and the comic? Who created this Superheroine? This work intends to shed a light on the myth of the Amazons as well as on the evolution of this American comic character.

  2. Characterisation of Ferrosilicon Dense Medium Separation Material

    International Nuclear Information System (INIS)

    Waanders, F. B.; Mans, A.

    2003-01-01

    Ferrosilicon is used in the dense medium separation of iron ore at Kumba resources, Sishen, South Africa. Due to high cost and losses that occur during use, maximum recovery by means of magnetic separation is aimed for. The purpose of this project was to determine the characteristics of the unused Fe-Si and then to characterise the changes that occur during storage and use thereof. Scanning electron microscopy was used to determine the composition of each sample, whilst Moessbauer spectroscopy yielded a two-sextet spectrum with hyperfine magnetic field strengths of 20 and 31 T, respectively, for the fresh samples. Additional hematite oxide peaks appeared in the Moessbauer spectra after use of the Fe-Si over a length of time, but this did not result in a dramatic degradation of the medium. No definite changes occurred during correct storage methods. It was, however, found that the biggest loss of Fe-Si was due to the abrasion of the particles, which resulted in the formation of an oxihydroxide froth, during the process.

  3. Novel approaches to microbial enhancement of oil recovery.

    Science.gov (United States)

    Kryachko, Yuriy

    2018-01-20

    Microbially enhanced oil recovery (MEOR) was shown to be feasible in a number of laboratory experiments and field trials. However, it has not been widely used in the oil industry because necessary conditions cannot always be easily established in an oil reservoir. Novel approaches to MEOR, which are based on newly discovered biosurfactant-mediated MEOR-mechanisms, are discussed in this review. Particularly, the possibility of combining MEOR with chemical enhancement of oil recovery in heterogeneous oil reservoirs, which involves rock surface wettability shifts and emulsion inversions, is discussed. In wider (centimeter/millimeter-scale) rock pores, the activity of (bio)surfactants and microbial cells attached to oil may allow releasing trapped oil blobs through oil-in-water emulsification. After no more oil can be emulsified, the addition of alkali or surfactants, which turn rock surface oil-wet, may help release oil droplets trapped in narrow (micrometer-scale) pores through coalescence of the droplets and water-in-oil emulsification. Experiments demonstrating the possibility of (bio)surfactant-mediated enhancement of immiscible gas-driven oil recovery are also reviewed. Interestingly, very low (bio)surfactant concentrations were shown to be needed for enhancement of immiscible gas-driven oil recovery. Some possible side effects of MEOR, such as unintended bioplugging and microbially influenced corrosion (MIC), are discussed as well. Crown Copyright © 2017. Published by Elsevier B.V. All rights reserved.

  4. Resolved Dual-Frequency Observations of the Debris Disk Around AU Mic: Strengths of Bodies in the Collisional Cascade

    Science.gov (United States)

    Carter, Evan; Hughes, A. Meredith; Daley, Cail; Flaherty, Kevin; Pan, Margaret; Schlichting, Hilke; Chiang, Eugene; MacGregor, Meredith Ann; Wilner, David; Dent, Bill; Carpenter, John; Andrews, Sean; Moor, Attila; Kospal, Agnes

    2018-01-01

    Debris disks are hallmarks of mature planetary systems, with second-generation dust produced via collisions between pluto-like planetesimals. The vertical structure of a debris disk encodes unique information about the dynamical state of the system, particularly at millimeter wavelengths where gravitational effects dominate over the effects of stellar radiation. We present 450 μm Atacama Large Millimeter/sub-millimeter Array (ALMA) observations of the edge-on debris disk around AU Mic, a nearby (d = 9.91 ± 0.10 pc) M1-type star. The 0.3'' angular resolution of the data allows us to spatially resolve the scale height of the disk, complementing previous observations at a wavelength of 1.3 mm. By resolving the vertical structure of the disk at these two widely-separated frequencies, we are able to spatially resolve the spectral index and study variations in the grain size distribution as a function of disk radius. The comparison of scale heights for two different wavelengths and therefore particle sizes also constrains the velocity dispersion as a function of grain size, which allows us to probe the strengths of bodies in the collisional cascade for the first time outside the Solar System.

  5. A library of MiMICs allows tagging of genes and reversible, spatial and temporal knockdown of proteins in Drosophila

    Science.gov (United States)

    Nagarkar-Jaiswal, Sonal; Lee, Pei-Tseng; Campbell, Megan E; Chen, Kuchuan; Anguiano-Zarate, Stephanie; Cantu Gutierrez, Manuel; Busby, Theodore; Lin, Wen-Wen; He, Yuchun; Schulze, Karen L; Booth, Benjamin W; Evans-Holm, Martha; Venken, Koen JT; Levis, Robert W; Spradling, Allan C; Hoskins, Roger A; Bellen, Hugo J

    2015-01-01

    Here, we document a collection of ∼7434 MiMIC (Minos Mediated Integration Cassette) insertions of which 2854 are inserted in coding introns. They allowed us to create a library of 400 GFP-tagged genes. We show that 72% of internally tagged proteins are functional, and that more than 90% can be imaged in unfixed tissues. Moreover, the tagged mRNAs can be knocked down by RNAi against GFP (iGFPi), and the tagged proteins can be efficiently knocked down by deGradFP technology. The phenotypes associated with RNA and protein knockdown typically correspond to severe loss of function or null mutant phenotypes. Finally, we demonstrate reversible, spatial, and temporal knockdown of tagged proteins in larvae and adult flies. This new strategy and collection of strains allows unprecedented in vivo manipulations in flies for many genes. These strategies will likely extend to vertebrates. DOI: http://dx.doi.org/10.7554/eLife.05338.001 PMID:25824290

  6. El cómic en la enseñanza del español como lengua extranjera

    Directory of Open Access Journals (Sweden)

    Jorge Catalá Carrasco

    2007-01-01

    Full Text Available La experiencia práctica que voy a relatar pretende mostrar las posibilidades que el cómic tiene, como producto cultural, dentro de las clases de español para extranjeros. Mi relación con las clases de español como lengua extranjera (E/LE se ciñe a estudiantes universitarios de un nivel avanzado, esto es, aquellos que han cursado las clases básicas de gramática y quieren profundizar en la lengua y la cultura hispánicas. Dentro de este marco es donde encuadro la presente experiencia. Los estudiantes con los que he trabajado provienen, en su mayoría, de The University of Georgia en los EE.UU. y cursan un semestre en Valencia (España para perfeccionar el idioma. Mi relación profesional con esta universidad norteamericana data de hace más de 4 años, primero como profesor asistente de español en los EE.UU. y luego como coordinador y profesor dentro del programa académico UGA en España, en Valencia.

  7. El cómic en la enseñanza del español como lengua extranjera

    Directory of Open Access Journals (Sweden)

    Jorge Catalá Carrasco

    2012-08-01

    Full Text Available La experiencia práctica que voy a relatar pretende mostrar las posibilidades que el cómic tiene, como producto cultural, dentro de las clases de español para extranjeros. Mi relación con las clases de español como lengua extranjera (E/LE se ciñe a estudiantes universitarios de un nivel avanzado, esto es,  aquellos que han cursado las clases básicas de gramática y quieren profundizar en la lengua y la cultura hispánicas. Dentro de este marco es donde encuadro la presente experiencia. Los estudiantes con los que he trabajado provienen, en su mayoría, de The University of Georgia en los EE.UU. y cursan un semestre en Valencia (España para perfeccionar el idioma. Mi relación profesional con esta universidad norteamericana data de hace más de 4 años, primero como profesor asistente de español en los EE.UU. y luego como  coordinador y profesor dentro del programa académico UGA en España, en Valencia.

  8. La intertextualidad en el cine de Álex de la Iglesia:El caso del cómic

    Directory of Open Access Journals (Sweden)

    Neftalí Pérez Franco

    2010-10-01

    Full Text Available Este artículo repasa la influencia del tebeo en las películas del director vasco, Alex de la Iglesia, cuyas primeras obras artísticas se deben a su condición de joven autor de historietas. El cine de este cineasta está marcado por claras reminiscencias provenientes de las viñetas: los superhéroes patéticos de Acción mutante se mueven por un contexto futurista muy del cómic de ciencia ficción; el humor estereotipado y los personajes grotescos del tebeo de la editorial Bruguera inundan todas sus comedias; o también son destacables los diversos homenajes narrativos o estéticos a la escuela franco-belga de Hergé y Goscinny. Esta fuerte influencia recorre toda su filmografía desde la mencionada ópera prima Acción mutante, hasta Crimen Ferpecto, pasando por títulos como El día de la bestia, Perdita Durango, Muertos de risa o La comunidad, hasta convertirse en un autor abanderado del fenómeno freak que marca tendencia en el cine español.

  9. El discurso político del Cómic sobre el pasado nacional. Tres lecturas del Siglo de Oro.

    Directory of Open Access Journals (Sweden)

    Isabelle Touton

    2012-07-01

    Full Text Available Este artículo se propone mostrar cómo la representación del pasado en el cómic, por medio de opciones estéticas y de recursos específicos a este arte, conlleva como cualquier relectura una dimensión política no siempre explícita. Para ello, nos hemos centrado en la reelaboración de tres “lugares de memoria” del Siglo de Oro (la España y la figura de Felipe II; los tercios de Flandes en tiempos de Felipe IV; Santa Teresa de Jesús en tres obras con objetivos, tonos, modalidades formales y dimensiones plásticas bastante alejados unos de otros: Felipe II (1999 de Antonio Hernández Palacios; El capitán Alatriste (2005, adaptación de la primera novela del ciclo de Pérez-Reverte, con guión Carlos Giménez y dibujos de Joan Mundet, y La vie passionnée de Thérèse d’Avila (1980 de la historietista francesa Claire Brétécher.

  10. Quantitative Recovery of Aeromonas hydrophila from Nsukka Sewage

    African Journals Online (AJOL)

    Sewage samples were analyzed for the recovery of Aeromonas hydrophila. The pH of the samples ranged from 8.2 - 9.6 and the temperature from 20.0 – 28.7. Samples were enriched in alkaline peptone water medium (pH 8.4) before plating on different selective media. Media tested for the recovery of Aeromonas ...

  11. Intel Many Integrated Core (MIC) architecture optimization strategies for a memory-bound Weather Research and Forecasting (WRF) Goddard microphysics scheme

    Science.gov (United States)

    Mielikainen, Jarno; Huang, Bormin; Huang, Allen H.

    2014-10-01

    The Goddard cloud microphysics scheme is a sophisticated cloud microphysics scheme in the Weather Research and Forecasting (WRF) model. The WRF is a widely used weather prediction system in the world. It development is a done in collaborative around the globe. The Goddard microphysics scheme is very suitable for massively parallel computation as there are no interactions among horizontal grid points. Compared to the earlier microphysics schemes, the Goddard scheme incorporates a large number of improvements. Thus, we have optimized the code of this important part of WRF. In this paper, we present our results of optimizing the Goddard microphysics scheme on Intel Many Integrated Core Architecture (MIC) hardware. The Intel Xeon Phi coprocessor is the first product based on Intel MIC architecture, and it consists of up to 61 cores connected by a high performance on-die bidirectional interconnect. The Intel MIC is capable of executing a full operating system and entire programs rather than just kernels as the GPU do. The MIC coprocessor supports all important Intel development tools. Thus, the development environment is familiar one to a vast number of CPU developers. Although, getting a maximum performance out of MICs will require using some novel optimization techniques. Those optimization techniques are discusses in this paper. The results show that the optimizations improved performance of the original code on Xeon Phi 7120P by a factor of 4.7x. Furthermore, the same optimizations improved performance on a dual socket Intel Xeon E5-2670 system by a factor of 2.8x compared to the original code.

  12. Anorexia-cachexia syndrome in hepatoma tumour-bearing rats requires the area postrema but not vagal afferents and is paralleled by increased MIC-1/GDF15.

    Science.gov (United States)

    Borner, Tito; Arnold, Myrtha; Ruud, Johan; Breit, Samuel N; Langhans, Wolfgang; Lutz, Thomas A; Blomqvist, Anders; Riediger, Thomas

    2017-06-01

    The cancer-anorexia-cachexia syndrome (CACS) negatively affects survival and therapy success in cancer patients. Inflammatory mediators and tumour-derived factors are thought to play an important role in the aetiology of CACS. However, the central and peripheral mechanisms contributing to CACS are insufficiently understood. The area postrema (AP) and the nucleus tractus solitarii are two important brainstem centres for the control of eating during acute sickness conditions. Recently, the tumour-derived macrophage inhibitory cytokine-1 (MIC-1) emerged as a possible mediator of cancer anorexia because lesions of these brainstem areas attenuated the anorectic effect of exogenous MIC-1 in mice. Using a rat hepatoma tumour model, we examined the roles of the AP and of vagal afferents in the mediation of CACS. Specifically, we investigated whether a lesion of the AP (APX) or subdiaphragmatic vagal deafferentation (SDA) attenuate anorexia, body weight, muscle, and fat loss. Moreover, we analysed MIC-1 levels in this tumour model and their correlation with tumour size and the severity of the anorectic response. In tumour-bearing sham-operated animals mean daily food intake significantly decreased. The anorectic response was paralleled by a significant loss of body weight and muscle mass. APX rats were protected against anorexia, body weight loss, and muscle atrophy after tumour induction. In contrast, subdiaphragmatic vagal deafferentation did not attenuate cancer-induced anorexia or body weight loss. Tumour-bearing rats had substantially increased MIC-1 levels, which positively correlated with tumour size and cancer progression and negatively correlated with food intake. These findings demonstrate the importance of the AP in the mediation of cancer-dependent anorexia and body weight loss and support a pathological role of MIC-1 as a tumour-derived factor mediating CACS, possibly via an AP-dependent action. © 2016 The Authors. Journal of Cachexia, Sarcopenia and Muscle

  13. Recovery and money management.

    Science.gov (United States)

    Rowe, Michael; Serowik, Kristin L; Ablondi, Karen; Wilber, Charles; Rosen, Marc I

    2013-06-01

    Social recovery and external money management are important approaches in contemporary mental health care, but little research has been done on the relationship between the two or on application of recovery principles to money management for people at risk of being assigned a representative payee or conservator. Out of 49 total qualitative interviews, 25 transcripts with persons receiving Social Security insurance or Social Security disability insurance who were at risk of being assigned a money manager were analyzed to assess the presence of recognized recovery themes. The recovery principles of self-direction and responsibility were strong themes in participant comments related to money management. Money management interventions should incorporate peoples' recovery-related motivations to acquire financial management skills as a means to direct and assume responsibility for one's finances. Staff involved in money management should receive training to support client's recovery-related goals. (PsycINFO Database Record (c) 2013 APA, all rights reserved).

  14. Coupling of MIC-3 overexpression with the chromosomes 11 and 14 root-knot nematode (RKN) (Meloidogyne incognita) resistance QTLs provides insights into the regulation of the RKN resistance response in Upland cotton (Gossypium hirsutum).

    Science.gov (United States)

    Wubben, Martin J; Callahan, Franklin E; Jenkins, Johnie N; Deng, Dewayne D

    2016-09-01

    Genetic analysis of MIC-3 transgene with RKN resistance QTLs provides insight into the resistance regulatory mechanism and provides a framework for testing additional hypotheses. Resistance to root-knot nematode (RKN) (Meloidogyne incognita) in Upland cotton (Gossypium hirsutum) is mediated by two major quantitative trait loci (QTL) located on chromosomes 11 and 14. The MIC-3 (Meloidogyne Induced Cotton3) protein accumulates specifically within the immature galls of RKN-resistant plants that possess these QTLs. Recently, we showed that MIC-3 overexpression in an RKN-susceptible cotton genotype suppressed RKN egg production but not RKN-induced root galling. In this study, the MIC-3 overexpression construct T-DNA in the single-copy transgenic line '14-7-1' was converted into a codominant molecular marker that allowed the marker assisted selection of F2:3 cotton lines, derived from a cross between 14-7-1 and M-240 RNR, having all possible combinations of the chromosomes 11 and 14 QTLs with and without the MIC-3 overexpression construct. Root-knot nematode reproduction (eggs g(-1) root) and severity of RKN-induced root galling were assessed in these lines. We discovered that the addition of MIC-3 overexpression suppressed RKN reproduction in lines lacking both resistance QTLs and in lines having only the chromosome 14 QTL, suggesting an additive effect of the MIC-3 construct with this QTL. In contrast, MIC-3 overexpression did not improve resistance in lines having the single chromosome 11 QTL or in lines having both resistance QTLs, suggesting an epistatic interaction between the chromosome 11 QTL and the MIC-3 construct. Overexpression of MIC-3 did not affect the severity of RKN-induced root galling regardless of QTL genotype. These data provide new insights into the relative order of action of the chromosomes 11 and 14 QTLs and their potential roles in regulating MIC-3 expression as part of the RKN resistance response.

  15. Pions in the nuclear medium

    International Nuclear Information System (INIS)

    Chanfray, G.

    1996-07-01

    We discuss various aspects of pion physics in the nuclear medium. We first study s-wave pion-nucleus interaction in connection with chiral symmetry restoration and quark condensate in the nuclear medium. We then address the question of p-wave pion-nucleus interaction and collective pionic modes in nuclei and draw the consequences for in medium ππ correlations especially in the scalar-isoscalar channel. We finally discuss the modification of the rho meson mass spectrum at finite density and/or temperature in connection with relativistic heavy ion collisions

  16. Tenth oil recovery conference

    International Nuclear Information System (INIS)

    Sleeper, R.

    1993-01-01

    The Tertiary Oil Recovery Project is sponsored by the State of Kansas to introduce Kansas producers to the economic potential of enhanced recovery methods for Kansas fields. Specific objectives include estimation of the state-wide tertiary oil resource, identification and evaluation of the most applicable processes, dissemination of technical information to producers, occasional collaboration on recovery projects, laboratory studies on Kansas applicable processes, and training of students and operators in tertiary oil recovery methods. Papers have been processed separately for inclusion on the data base

  17. Medium modifications of vector mesons

    International Nuclear Information System (INIS)

    Pant, L.M.

    2004-01-01

    The omega photoproduction in nuclear medium with the ELSA facility at Bonn and the present status of the HADES collaboration to investigate the in-medium hadron properties in proton, heavy ions and hadron induced reactions at GSI, Darmstadt are presented. Efforts are under way to utilise the electron beam at Indore for experimental hadron physics in order to step into the intermediate energy nuclear physics regime. The skeletal outline of the high energy electron beam now available at CAT, Indore is discussed

  18. Medium effects in direct reactions

    International Nuclear Information System (INIS)

    Karakoc, M; Bertulani, C

    2013-01-01

    We discuss medium corrections of the nucleon-nucleon (NN) cross sections and their influence on direct reactions at intermediate energies ≳50 MeV/nucleon. The results obtained with free NN cross sections are compared with those obtained with a geometrical treatment of Pauli-blocking and Dirac-Bruecker methods. We show that medium corrections may lead to sizable modifications for collisions at intermediate energies and that they are more pronounced in reactions involving weakly bound nuclei.

  19. Feasibility of direct electrochemical recovery of fission platinoids (Ru, Rh, Pd) from nitric acid solution

    International Nuclear Information System (INIS)

    Jayakumar, M.; Venkatesan, K.A.; Srinivasan, T.G.; Vasudeva Rao, P.R.

    2010-01-01

    Electrodeposition behavior of ruthenium, rhodium and palladium from nitric acid medium at various applied potentials was studied at stainless steel electrode and the results on the recovery of these fission platinoids are reported in this paper. (author)

  20. Plasma MIC-1 and PAPP-a levels are decreased among women presenting to an early pregnancy assessment unit, have fetal viability confirmed but later miscarry.

    Directory of Open Access Journals (Sweden)

    Tu'uhevaha J Kaitu'u-Lino

    Full Text Available We have recently shown first trimester Macrophage inhibitory cytokine-1 (MIC-1 and Pregnancy Associated Plasma Protein-A (PAPP-A serum concentrations are depressed among asymptomatic women destined to miscarry. Here we examined whether plasma levels of MIC-1 and PAPP-A are depressed among women presenting to an Early Pregnancy Assessment Unit (EPAU, noted to have a confirmed viable fetus, but subsequently miscarry.We performed a prospective cohort study, recruiting 462 women in the first trimester presenting to EPAU and had fetal viability confirmed by ultrasound. We obtained plasma samples on the same day and measured MIC-1, PAPP-A and human chorionic gonadotrophin (hCG, grouping the cohort according to whether they later miscarried or not. To correct for changes in analyte levels across gestation, we expressed the data as Multiples of the normal Median (MoMs.We recruited 462 participants presenting to EPAU at 5-12 weeks gestation. Most (80% presented with symptoms of threatened miscarriage (e.g. abdominal pain, vaginal bleeding. 34 (7.4% subsequently miscarried. Median plasma MIC-1 levels among those who miscarried were 50% of those with ongoing pregnancies (Miscarriage cohort MoM 0.50 (25(th-75(th centiles: 0.29-1.33 vs ongoing pregnancies MoM 1.00 (0.65-1.38; p=0.0025. Median plasma PAPP-A MoMs among those who miscarried was 0.57 (0.00-1.12, significantly lower than those with ongoing pregnancies (MoMs 1.00 (0.59-1.59; p=0.036. Plasma hCG levels were also significantly depressed among those who miscarried compared to those with ongoing pregnancies. However, the performance of MIC-1 as a diagnostic marker to predict miscarriage in this cohort was modest, and not improved with the addition of hCG.MIC-1 and PAPP-A levels are significantly depressed in women presenting to EPAU with ultrasound evidence of fetal viability, but later miscarry. While they are unlikely to be useful as predictive biomarkers in this clinical setting, they probably play

  1. Imaging resilience and recovery in alcohol dependence.

    Science.gov (United States)

    Charlet, Katrin; Rosenthal, Annika; Lohoff, Falk W; Heinz, Andreas; Beck, Anne

    2018-05-09

    Resilience and recovery are of increasing importance in the field of alcohol dependence (AD). This paper describes how imaging studies in man can be used to assess the neurobiological correlates of resilience and, if longitudinal, of disease trajectories, progression rates and markers for recovery to inform treatment and prevention options. Original articles on recovery and resilience in alcohol addiction and its neurobiological correlates were identified from 'PubMed' and have been analyzed and condensed within a systematic literature review. Findings deriving from (f)MRI and PET studies have identified links between increased resilience and less task-elicited neural activation within the basal ganglia, and benefits of heightened neural prefrontal cortex (PFC) engagement regarding resilience in a broader sense, namely resilience against relapse in early abstinence of AD. Furthermore, findings consistently propose at least partial recovery of brain glucose metabolism and executive and general cognitive functioning, as well as structural plasticity effects throughout the brain of alcohol-dependent patients during the course of short, medium and long-term abstinence, even when patients only lowered their alcohol consumption to a moderate level. Additionally, specific factors were found that appear to influence these observed brain recovery processes in AD, e.g. genotype-dependent neuronal (re)growth, gender-specific neural recovery effects, critical interfering effects of psychiatric comorbidities, additional smoking or marijuana influences, or adolescent alcohol abuse. Neuroimaging research has uncovered neurobiological markers that appear to be linked to resilience and improved recovery capacities that are furthermore influenced by various factors such as gender or genetics. Consequently, future system-oriented approaches may help to establish a broad neuroscience-based research framework for alcohol dependence. This article is protected by copyright. All rights

  2. Illness management and recovery

    DEFF Research Database (Denmark)

    Dalum, Helle Stentoft; Waldemar, Anna Kristine; Korsbek, Lisa

    2018-01-01

    OBJECTIVE: Illness Management and Recovery (IMR) is a psychosocial intervention with a recovery-oriented approach. The program has been evaluated in different settings; however evidence for the effects of IMR is still deficient. The aim of this trial was to investigate the benefits and harms...

  3. Disidencia sexual en el cómic alemán contemporáneo: el caso de Ralf König

    OpenAIRE

    Saxe, Facundo

    2016-01-01

    Este trabajo aborda la representación de la sexualidad disidente en el cómic alemán contemporáneo. Se analiza la obra del autor alemán Ralf König desde una perspectiva propia de los estudios queer y la disidencia de sexo-género. A través de un recorrido crítico se conceptualiza la figura del autor en su campo cultural y su proyección vinculada a las sexualidades disidentes en Europa y a la tradición del cómic en Alemania. Como caso paradigmático se realiza un análisis textual d...

  4. Flares on dMe stars: IUE and optical observations of At Mic, and comparison of far-ultraviolet stellar and solar flares

    International Nuclear Information System (INIS)

    Bromage, G.E.; Phillips, K.J.H.; Dufton, P.L.; Kingston, A.E.

    1986-01-01

    The paper concerns observations of a large flare event on the dMe star At Mic, detected by the International Ultraviolet Explorer. The far-ultraviolet spectra of the flare is compared with those of other stellar flares, and also with a large solar flare recorded by the Skylab mission in 1973. The quiescent-phase optical and ultraviolet spectrum of the same dMe flare star is discussed. (U.K.)

  5. Minimum inhibitory (MIC) and minimum microbicidal concentration (MMC) of polihexanide and triclosan against antibiotic sensitive and resistant Staphylococcus aureus and Escherichia coli strains

    Science.gov (United States)

    Assadian, Ojan; Wehse, Katrin; Hübner, Nils-Olaf; Koburger, Torsten; Bagel, Simone; Jethon, Frank; Kramer, Axel

    2011-01-01

    Background: An in-vitro study was conducted investigating the antimicrobial efficacy of polihexanide and triclosan against clinical isolates and reference laboratory strains of Staphylococcus aureus and Escherichia coli. Methods: The minimal inhibitory concentration (MIC) and the minimal microbicidal concentration (MMC) were determined following DIN 58940-81 using a micro-dilution assay and a quantitative suspension test following EN 1040. Polihexanide was tested in polyethylene glycol 4000, triclosan in aqueous solutions. Results: Against all tested strains the MIC of polihexanide ranged between 1–2 µg/mL. For triclosan the MICs varied depending on strains ranging between 0.5 µg/mL for the reference strains and 64 µg/mL for two clinical isolates. A logRF >5 without and logRF >3 with 0.2% albumin burden was achieved at 0.6 µg/mL triclosan. One exception was S. aureus strain H-5-24, where a triclosan concentration of 0.6 µg/mL required 1 minute without and 10 minutes with albumin burden to achieve the same logRFs. Polihexanide achieved a logRF >5 without and logRF >3 with albumin burden at a concentration of 0.6 µg/mL within 30 sec. The exception was the North-German epidemic MRSA strain, were an application time of 5 minutes was required. Conclusion: The clinical isolates of E. coli generally showed higher MICs against triclosan, both in the micro-dilution assay as well in the quantitative suspension test than comparable reference laboratory strains. For polihexanide and triclosan strain dependant susceptibility was shown. However, both antimicrobial compounds are effective when used in concentrations common in practice. PMID:22242087

  6. Tratamiento quirúrgico de un aneurisma micótico en paciente con riñón en herradura por vía retroperitoneal

    Directory of Open Access Journals (Sweden)

    Ricardo Muñoz-García

    2013-01-01

    Full Text Available Presentamos el caso de un paciente de 73 años diagnosticado de un aneurisma de aorta abdominal micótico que presenta un riñón en herradura. El paciente fue intervenido por vía retroperitoneal, realizándose resección del aneurisma, con postoperatorio irregular, pero finalmente siendo dado de alta sin incidencias y asintomático.

  7. The Widely Used ATB FUNGUS 3 Automated Readings in China and Its Misleading High MICs of Candida spp. to Azoles: Challenges for Developing Countries' Clinical Microbiology Labs

    OpenAIRE

    Zhang, Li; Wang, He; Xiao, Meng; Kudinha, Timothy; Mao, Lei-Li; Zhao, Hao-Ran; Kong, Fanrong; Xu, Ying-Chun

    2014-01-01

    The rapid development in the clinical microbiology diagnostic assays presents more challenges for developing countries than for the developed world, especially in the area of test validation before the introduction of new tests. Here we report on the misleading high MICs of Candida spp. to azoles using the ATB FUNGUS 3 (bioMérieux, La Balme-les Grottes, France) with automated readings in China to highlight the dangers of introducing a diagnostic assay without validation. ATB FUNGUS 3 is the m...

  8. Assessing the Accuracy of High Resolution Digital Surface Models Computed by PhotoScan® and MicMac® in Sub-Optimal Survey Conditions

    Directory of Open Access Journals (Sweden)

    Marion Jaud

    2016-06-01

    Full Text Available For monitoring purposes and in the context of geomorphological research, Unmanned Aerial Vehicles (UAV appear to be a promising solution to provide multi-temporal Digital Surface Models (DSMs and orthophotographs. There are a variety of photogrammetric software tools available for UAV-based data. The objective of this study is to investigate the level of accuracy that can be achieved using two of these software tools: Agisoft PhotoScan® Pro and an open-source alternative, IGN© MicMac®, in sub-optimal survey conditions (rugged terrain, with a large variety of morphological features covering a range of roughness sizes, poor GPS reception. A set of UAV images has been taken by a hexacopter drone above the Rivière des Remparts, a river on Reunion Island. This site was chosen for its challenging survey conditions: the topography of the study area (i involved constraints on the flight plan; (ii implied errors on some GPS measurements; (iii prevented an optimal distribution of the Ground Control Points (GCPs and; (iv was very complex to reconstruct. Several image processing tests are performed with different scenarios in order to analyze the sensitivity of each software package to different parameters (image quality, numbers of GCPs, etc.. When computing the horizontal and vertical errors within a control region on a set of ground reference targets, both methods provide rather similar results. A precision up to 3–4 cm is achievable with these software packages. The DSM quality is also assessed over the entire study area comparing PhotoScan DSM and MicMac DSM with a Terrestrial Laser Scanner (TLS point cloud. PhotoScan and MicMac DSM are also compared at the scale of particular features. Both software packages provide satisfying results: PhotoScan is more straightforward to use but its source code is not open; MicMac is recommended for experimented users as it is more flexible.

  9. Multicenter evaluation of MIC distributions for epidemiologic cutoff value definition to detect amphotericin B, posaconazole, and itraconazole resistance among the most clinically relevant species of Mucorales.

    Science.gov (United States)

    Espinel-Ingroff, A; Chakrabarti, A; Chowdhary, A; Cordoba, S; Dannaoui, E; Dufresne, P; Fothergill, A; Ghannoum, M; Gonzalez, G M; Guarro, J; Kidd, S; Lass-Flörl, C; Meis, J F; Pelaez, T; Tortorano, A M; Turnidge, J

    2015-03-01

    Clinical breakpoints (CBPs) have not been established for the Mucorales and any antifungal agent. In lieu of CBPs, epidemiologic cutoff values (ECVs) are proposed for amphotericin B, posaconazole, and itraconazole and four Mucorales species. Wild-type (WT) MIC distributions (organisms in a species-drug combination with no detectable acquired resistance mechanisms) were defined with available pooled CLSI MICs from 14 laboratories (Argentina, Australia, Canada, Europe, India, Mexico, and the United States) as follows: 10 Apophysomyces variabilis, 32 Cunninghamella bertholletiae, 136 Lichtheimia corymbifera, 10 Mucor indicus, 123 M. circinelloides, 19 M. ramosissimus, 349 Rhizopus arrhizus, 146 R. microsporus, 33 Rhizomucor pusillus, and 36 Syncephalastrum racemosum isolates. CLSI broth microdilution MICs were aggregated for the analyses. ECVs comprising ≥95% and ≥97.5% of the modeled populations were as follows: amphotericin B ECVs for L. corymbifera were 1 and 2 μg/ml, those for M. circinelloides were 1 and 2 μg/ml, those for R. arrhizus were 2 and 4 μg/ml, and those for R. microsporus were 2 and 2 μg/ml, respectively; posaconazole ECVs for L. corymbifera were 1 and 2, those for M. circinelloides were 4 and 4, those for R. arrhizus were 1 and 2, and those for R. microsporus were 1 and 2, respectively; both itraconazole ECVs for R. arrhizus were 2 μg/ml. ECVs may aid in detecting emerging resistance or isolates with reduced susceptibility (non-WT MICs) to the agents evaluated. Copyright © 2015, American Society for Microbiology. All Rights Reserved.

  10. Characterization of diode valve in medium voltage dc/dc converter for wind turbines

    DEFF Research Database (Denmark)

    Dincan, Catalin Gabriel; Kjær, Philip Carne

    2016-01-01

    This paper proposes a methodology for characterization of medium voltage (MV), medium frequency (MF) rectifier diode valve. The intended application is for 10MW dc/dc converters used in DC offshore wind turbines. Sensitivity to semiconductor component parameter variation, snubber component tolera...... tolerance, influence of temperature and stray capacitance are analyzed. It is concluded that the largest impact on sensitivity is given by reverse recovery charge variation and differences of temperature between adjacent devices....

  11. Anorexia-cachexia and obesity treatment may be two sides of the same coin: role of the TGF-b superfamily cytokine MIC-1/GDF15.

    Science.gov (United States)

    Tsai, V W W; Lin, S; Brown, D A; Salis, A; Breit, S N

    2016-02-01

    Anorexia-cachexia associated with cancer and other diseases is a common and often fatal condition representing a large area of unmet medical need. It occurs most commonly in advanced cancer and is probably a consequence of molecules released by tumour cells, or tumour-associated interstitial or immune cells. These may then act directly on muscle to cause atrophy and/or may cause anorexia, which then leads to loss of both fat and lean mass. Although the aetiological triggers for this syndrome are not well characterized, recent data suggest that MIC-1/GDF15, a transforming growth factor-beta superfamily cytokine produced in large amounts by cancer cells and as a part of other disease processes, may be an important trigger. This cytokine acts on feeding centres in the hypothalamus and brainstem to cause anorexia leading to loss of lean and fat mass and eventually cachexia. In animal studies, the circulating concentrations of MIC-1/GDF15 required to cause this syndrome are similar to those seen in patients with advanced cancer, and at least some epidemiological studies support an association between MIC-1/GDF15 serum levels and measures of nutrition. This article will discuss its mechanisms of central appetite regulation, and the available data linking this action to anorexia-cachexia syndromes that suggest it is a potential target for therapy of cancer anorexia-cachexia and conversely may also be useful for the treatment of severe obesity.

  12. National and Gender Measurement Invariance of the Utrecht-Management of Identity Commitments Scale (U-MICS): A 10-Nation Study With University Students.

    Science.gov (United States)

    Crocetti, Elisabetta; Cieciuch, Jan; Gao, Cheng-Hai; Klimstra, Theo; Lin, Ching-Ling; Matos, Paula Mena; Morsünbül, Ümit; Negru, Oana; Sugimura, Kazumi; Zimmermann, Grégoire; Meeus, Wim

    2015-12-01

    The purpose of this study was to examine the psychometric properties of the Utrecht-Management of Identity Commitments Scale (U-MICS), a self-report measure aimed at assessing identity processes of commitment, in-depth exploration, and reconsideration of commitment. We tested its factor structure in university students from a large array of cultural contexts, including 10 nations located in Europe (i.e., Italy, the Netherlands, Poland, Portugal, Romania, and Switzerland), Middle East (i.e., Turkey), and Asia (i.e., China, Japan, and Taiwan). Furthermore, we tested national and gender measurement invariance. Participants were 6,118 (63.2% females) university students aged from 18 to 25 years (Mage = 20.91 years). Results indicated that the three-factor structure of the U-MICS fitted well in the total sample, in each national group, and in gender groups. Furthermore, national and gender measurement invariance were established. Thus, the U-MICS can be fruitfully applied to study identity in university students from various Western and non-Western contexts. © The Author(s) 2015.

  13. Chulos y novios en viñetas. Cómo dedicarse al cómic (gay y no morir en el intento

    Directory of Open Access Journals (Sweden)

    Sebas Martín (autor de cómics

    2009-01-01

    Full Text Available Vivir del cómic es, de por sí, un imposible, pero las dificultades se acrecientan si el objetivo de un autor es dedicarse al cómic gay. En este artículo de cariz autobiográfico, se relatan los obstáculos y los éxitos que han marcado la trayectoria profesional de su autor, desde sus inicios, en los años 80, como creador de un fanzine, hasta la proliferación de proyectos que marcan los 2000. Con todo, se traza un recorrido por el panorama cultural e ideológico de la España de las últimas décadas, a través del cual asistimos a la lenta pero constante superación de los prejuicios que aún hoy rodean tanto el género del cómic como el mundo gay.

  14. STUDY OF THE ISOLATES OF SUSPECTED VAP, PREVALENCE OF THE DIFFERENT ORGANISMS AND MIC PATTERNS IN A TERTIARY CARE HOSPITAL

    Directory of Open Access Journals (Sweden)

    Swagnik Roy

    2017-01-01

    Full Text Available BACKGROUND The development of nosocomial infections mostly ventilator-associated pneumonia due to prolonged stay in the ICUs varies grossly in different outcomes including increased morbidity and mortality. The American Thoracic Society (ATS guidelines recommend that quantitative cultures can be performed on ETA or samples collected either bronchoscopically or nonbronchosopically. 1 More importantly, recent small trials have repeatedly shown that there is no advantage of bronchoscopic cultures over quantitative endotracheal aspirate. 2,3,4 Detection of causative organisms and their antibiotic MIC determination is absolutely necessary to initiate the specific antibiotic with appropriate dose thereby reducing the adverse effects of inadequate antibiotic treatment on the patient prognosis. MATERIALS AND METHODS The prospective study was carried out during the period from August 2012 to January 2015 in Department of Microbiology from the samples those were received as a routine culture from VAP suspected patients from the ICU. There were 373 samples from which 123 were culture positives. Inclusion criteria were all the patients 18 years and more age group who were intubated in mechanical ventilator and others were excluded in the study. Clinical Pulmonary Infection Score (CPIS was given to each patient included in the study on daily basis. CPIS of greater than six was used as diagnostic criteria for VAP. 5 Clinically diagnosed ventilator-associated pneumonia were observed and clinical parameters were recorded from their medical records and bedside charts. All patients with clinical and radiological signs suggestive of pneumonia on admission. Endotracheal aspirate was collected by using a 22-inch Romsons suction catheter. Chest vibration or percussion for 10 mins. was used. Only 1 ETA sample was collected from each patient and was immediately taken to the laboratory for processing. RESULTS Klebsiella pneumonia was isolated 39.02%, Pseudomonas

  15. Properties of the nuclear medium

    International Nuclear Information System (INIS)

    Baldo, M; Burgio, G F

    2012-01-01

    We review our knowledge on the properties of the nuclear medium that have been studied, over many years, on the basis of many-body theory, laboratory experiments and astrophysical observations. Throughout the presentation particular emphasis is placed on the possible relationship and links between the nuclear medium and the structure of nuclei, including the limitations of such an approach. First we consider the realm of phenomenological laboratory data and astrophysical observations and the hints they can give on the characteristics that the nuclear medium should possess. The analysis is based on phenomenological models, that however have a strong basis on physical intuition and an impressive success. More microscopic models are also considered, and it is shown that they are able to give invaluable information on the nuclear medium, in particular on its equation of state. The interplay between laboratory experiments and astrophysical observations is particularly stressed, and it is shown how their complementarity enormously enriches our insights into the structure of the nuclear medium. We then introduce the nucleon–nucleon interaction and the microscopic many-body theory of nuclear matter, with a critical discussion about the different approaches and their results. The Landau–Fermi liquid theory is introduced and briefly discussed, and it is shown how fruitful it can be in discussing the macroscopic and low-energy properties of the nuclear medium. As an illustrative example, we discuss neutron matter at very low density, and it is shown how it can be treated within the many-body theory. The general bulk properties of the nuclear medium are reviewed to indicate at which stage of our knowledge we stand, taking into account the most recent developments both in theory and experiments. A section is dedicated to the pairing problem. The connection with nuclear structure is then discussed, on the basis of the energy density functional method. The possibility of

  16. Energy recovery from wastes

    International Nuclear Information System (INIS)

    De Stefanis, P.

    1999-01-01

    In this paper are reported analysis of some energy recovery form wastes plants. In this work are considered materials and energy flows, environmental impacts and related treatment costs and financial resources [it

  17. Recovery Audit Program

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Recovery Audit Programs mission is to identify and correct Medicare improper payments through the efficient detection and collection of overpayments made on...

  18. FEMA Disaster Recovery Centers

    Data.gov (United States)

    Department of Homeland Security — This is a search site for FEMA's Disaster Recovery Centers (DRC). A DRC is a readily accessible facility or mobile office set up by FEMA where applicants may go for...

  19. Spatially Dispersed Employee Recovery

    DEFF Research Database (Denmark)

    Hvass, Kristian Anders; Torfadóttir, Embla

    2014-01-01

    Employee recovery addresses either employee well-being or management's practices in aiding employees in recovering themselves following a service failure. This paper surveys the cabin crew at a small, European, low-cost carrier and investigates employees' perceptions of management practices to aid...... personnel achieve service recovery. Employee recovery within service research often focuses on front-line employees that work in a fixed location, however a contribution to the field is made by investigating the recovery of spatially dispersed personnel, such as operational personnel in the transport sector......, who have a work place away from a fixed or central location and have minimal management contact. Results suggest that the support employees receive from management, such as recognition, information sharing, training, and strategic awareness are all important for spatially dispersed front...

  20. Recovery Action Mapping Tool

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Recovery Action Mapping Tool is a web map that allows users to visually interact with and query actions that were developed to recover species listed under the...

  1. Waste heat recovery for offshore applications

    DEFF Research Database (Denmark)

    Pierobon, Leonardo; Kandepu, Rambabu; Haglind, Fredrik

    2012-01-01

    vary in the range 20-30%. There are several technologies available for onshore gas turbines (and low/medium heat sources) to convert the waste heat into electricity. For offshore applications it is not economical and practical to have a steam bottoming cycle to increase the efficiency of electricity...... production, due to low gas turbine outlet temperature, space and weight restrictions and the need for make-up water. A more promising option for use offshore is organic Rankine cycles (ORC). Moreover, several oil and gas platforms are equipped with waste heat recovery units to recover a part of the thermal...... energy in the gas turbine off-gas using heat exchangers, and the recovered thermal energy acts as heat source for some of the heat loads on the platform. The amount of the recovered thermal energy depends on the heat loads and thus the full potential of waste heat recovery units may not be utilized...

  2. Incineration with energy recovery

    Energy Technology Data Exchange (ETDEWEB)

    Mahoney, T.G.

    1986-02-01

    Motherwell Bridge Tacol Ltd. operate a 'Licence Agreement' with Deutsche Babcock Anlagen of Krefeld, West Germany, for the construction of Municipal Refuse Incineration plant and Industrial Waste plant with or without the incorporation of waste heat recovery equipment. The construction in the UK of a number of large incineration plants incorporating the roller grate incinerator unit is discussed. The historical background, combustion process, capacity, grate details, refuse analysis and use as fuel, heat recovery and costs are outlined.

  3. 1 Medium Regiment, (SAHA), SAA

    African Journals Online (AJOL)

    Scientia Militaria: South African Journal of Military Studies. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 16, No 4 (1986) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register. 1 Medium Regiment, (S.A.H.A.), ...

  4. Hadron photoproduction at medium energy

    International Nuclear Information System (INIS)

    Dainton, J.B.

    1985-04-01

    Results from measurements of multibody photoproduction at medium incident photon energy (2.8 to 4.8 GeV) are presented and discussed. Particular emphasis is placed on topics which are not well understood and which therefore motivate experiments with the upgraded electron accelerator and storage ring ELSA at the University of Bonn, FR Germany. (author)

  5. Animal Locomotion in Different Mediums

    Indian Academy of Sciences (India)

    Wetlands are repositories of unique biodiversity. Wetlandorganisms are well adapted to their habitat, lying at theinterface of aquatic and terrestrial environments. In order tounderstand their adaptations in a better way, it is essential tograsp the basic properties of the medium in which variousorganisms live. This is attempted ...

  6. Holographic Renormalization in Dense Medium

    International Nuclear Information System (INIS)

    Park, Chanyong

    2014-01-01

    The holographic renormalization of a charged black brane with or without a dilaton field, whose dual field theory describes a dense medium at finite temperature, is investigated in this paper. In a dense medium, two different thermodynamic descriptions are possible due to an additional conserved charge. These two different thermodynamic ensembles are classified by the asymptotic boundary condition of the bulk gauge field. It is also shown that in the holographic renormalization regularity of all bulk fields can reproduce consistent thermodynamic quantities and that the Bekenstein-Hawking entropy is nothing but the renormalized thermal entropy of the dual field theory. Furthermore, we find that the Reissner-Nordström AdS black brane is dual to a theory with conformal matter as expected, whereas a charged black brane with a nontrivial dilaton profile is mapped to a theory with nonconformal matter although its leading asymptotic geometry still remains as AdS space

  7. Medium modifications with recoil polarization

    Energy Technology Data Exchange (ETDEWEB)

    Brand, J.F.J. van den [Nationaal Instituut voor Kernfysica en Hoge Energiefysica, Amsterdam (Netherlands); Ent, R. [CEBAF, Newport News, VA (United States)

    1994-04-01

    The authors show that the virtual Compton scattering process allows for a precise study of the off-shell electron-nucleon vertex. In a separable model, they show the sensitivity to new unconstrained structure functions of the nucleon, beyond the usual Dirac and Pauli form factors. In addition, they show the sensitivity to bound nucleon form factors using the reaction 4He({rvec e},e{prime},{rvec p}){sup 3}H. A nucleon embedded in a nucleus represents a complex system. Firstly, the bound nucleon is necessarily off-shell and in principle a complete understanding of the dynamical structure of the nucleon is required in order to calculate its off-shell electromagnetic interaction. Secondly, one faces the possibility of genuine medium effects, such as for example quark-exchange contributions. Furthermore, the electromagnetic coupling to the bound nucleon is dependent on the nuclear dynamics through the self-energy of the nucleon in the nuclear medium.

  8. Medium modifications with recoil polarization

    International Nuclear Information System (INIS)

    Brand, J.F.J. van den; Ent, R.

    1994-01-01

    The authors show that the virtual Compton scattering process allows for a precise study of the off-shell electron-nucleon vertex. In a separable model, they show the sensitivity to new unconstrained structure functions of the nucleon, beyond the usual Dirac and Pauli form factors. In addition, they show the sensitivity to bound nucleon form factors using the reaction 4He(rvec e,e',rvec p) 3 H. A nucleon embedded in a nucleus represents a complex system. Firstly, the bound nucleon is necessarily off-shell and in principle a complete understanding of the dynamical structure of the nucleon is required in order to calculate its off-shell electromagnetic interaction. Secondly, one faces the possibility of genuine medium effects, such as for example quark-exchange contributions. Furthermore, the electromagnetic coupling to the bound nucleon is dependent on the nuclear dynamics through the self-energy of the nucleon in the nuclear medium

  9. Moellerella wisconsensis: identification, natural antibiotic susceptibility and its dependency on the medium applied.

    Science.gov (United States)

    Stock, Ingo; Falsen, Enevold; Wiedemann, Bernd

    2003-01-01

    The present study establishes a data compilation on biochemical features and natural antibiotic susceptibilities of Moellerella wisconsensis strains. 17 moellerellae isolated from humans (n = 11), food (n = 5) and water (n = 1) were tested. Identification was carried out using two commercially available systems and conventional tests. MIC determinations of 74 antibiotics were performed applying a microdilution procedure in Cation-adjusted Mueller Hinton broth and IsoSensitest broth. M. wisconsensis was naturally sensitive to doxycycline, minocycline, all tested aminoglycosides, numerous beta-lactams, all fluoroquinolones, folate-pathway inhibitors, chloramphenicol and nitrofurantoin. Natural resistance was found with oxacillin, penicillin G, all tested macrolides, lincomycin, streptogramins, ketolides, glycopeptides, fusidic acid, linezolid and rifampicin. Medium-dependent differences in susceptibility affecting clinical assessment criteria were seen with tetracycline, clindamycin and fosfomycin. From the data of the present study it is possible that some moellerellae are misidentified as Klebsiella pneumoniae subsp. ozaenae.

  10. Medium Theory and Social Systems

    DEFF Research Database (Denmark)

    Tække, Jesper

      the  possibility  for  observation both of a social micro and a social macro level from a medium perspective. In the next  section  the paper  frames  the macro  level by  a  tentative  synthesis of  the medium  theory  and  the  sociological systems theory briefly describing a socio......-evolutionary process where new media alter  the societal capacity to handle complexity  in  time and space.  In  this section it becomes probable  that  by  means  of  different  media,  social  systems  give  different  possibilities  for  actual  social  performance.  In a way,  social  systems  themselves can be......  seen as medium  for  formation. Finally  the  paper  takes  the micro  level  perspective  by  applying  the  theory  to  newsgroups,  interpreting  them as self-organizing interactive systems giving a differentiated and diversified scope for social  inclusion.  ...

  11. Absence of methylation of a CpG-rich region at the 5' end of the MIC2 gene on the active X, the inactive X, and the Y chromosome

    International Nuclear Information System (INIS)

    Goodfellow, P.J.; Mondello, C.; Darling, S.M.; Pym, B.; Little, P.; Goodfellow, P.N.

    1988-01-01

    The authors have identified and characterized a Hpa II tiny fragment (HTF) island associated with the promoter region of the pseudoautosomal gene MIC2. The MIC2 HTF island is unmethylated on both the active and inactive X chromosome and is similarly unmethylated on the Y chromosome. Unlike the majority of genes borne on the X chromosome, MIC2 fails to undergo X chromosome inactivation. HTF islands associated with X chromosome-liked genes that are inactivated are highly methylated on the inactive or transcriptionally silent homologue. The failure of MIC2 to undergo X chromosome inactivation correlates with the lack of methylation of HTF island at the 5' end of the gene. These results provide further evidence that DNA methylation plays an important role in the phenomenon of X chromosome inactivation

  12. Ecological recovery in ERA

    DEFF Research Database (Denmark)

    EFSA Scientific Committee (Scientific Committee); Topping, Christopher John

    2016-01-01

    knowledge and data retrieved from the literature. Finally, the information presented in this opinion was reviewed by experts from the relevant EFSA Panels, European risk assessment bodies and through an open consultation requesting input from stakeholders. A conceptual framework was developed to address...... recognises the importance of more integrated ERAs considering both the local and landscape scales, as well as the possible co-occurrence of multiple potential stressors that fall under the remit of EFSA, which are important when addressing ecological recovery. In this scientific opinion, the Scientific...... Committee gathered scientific knowledge on the potential for the recovery of non-target organisms for the further development of ERA. Current EFSA guidance documents and opinions were reviewed on how ecological recovery is addressed in ERA schemes. In addition, this scientific opinion is based on expert...

  13. Recovery of personal neglect.

    Science.gov (United States)

    Iosa, Marco; Guariglia, Cecilia; Matano, Alessandro; Paolucci, Stefano; Pizzamiglio, Luigi

    2016-12-01

    Extrapersonal unilateral spatial neglect after stroke is associated to a poor rehabilitation outcome. Minor attention has been paid to the recovery of personal neglect, to its relationship with the recovery of extrapersonal neglect and of independency in activities of daily living. The present study aims at evaluating whether there is an association between recovery of extrapersonal and personal neglect. The secondary aim was to investigate if personal neglect may affect the effectiveness of neurorehabilitation in patients with subacute stroke. Observational study. Neurorehabilitation Hospital in Rome, Italy, inpatients. A sample of 49 patients with unilateral spatial neglect resulting from right ischemic cerebral infarction was enrolled in this study, divided into three subgroups according to the presence and the degree of personal neglect, and evaluated pre and postneurorehabilitation. Personal neglect was evaluated using Zoccolotti and Judica's Scale, extrapersonal neglect using Letter Cancellation Test, Barrage Test, Sentence Reading Test and Wundt-Jastrow Area Illusion Test. Barthel Index (BI), Rivermead Mobility Index, and Canadian Neurological Scale were also administered. Results showed the following: 1) recovery of personal neglect was not significantly correlated with that of extrapersonal neglect, despite both the disorders were ameliorated after a "non-specific" rehabilitation treatment; 2) personal neglect per se was not an additional negative prognostic factor in the rehabilitation findings. Our results suggested that the recoveries of the two types of neglect are independent from each other, and that the presence of personal neglect does not imply significant additional problems to the functional outcomes. Our study highlighted the need of novel tools to assess the presence and to improve the recovery of personal neglect.

  14. Medium energy ion scattering (MEIS)

    International Nuclear Information System (INIS)

    Dittmann, K.; Markwitz, A.

    2009-01-01

    This report gives an overview about the technique and experimental study of medium energy ion scattering (MEIS) as a quantitative technique to determine and analyse the composition and geometrical structure of crystalline surfaces and near surface-layers by measuring the energy and yield of the backscattered ions. The use of a lower energy range of 50 to 500 keV accelerated ions impinging onto the target surface and the application of a high-resolution electrostatic energy analyser (ESA) makes medium energy ion scattering spectroscopy into a high depth resolution and surface-sensitive version of RBS with less resulting damage effects. This report details the first steps of research in that field of measurement technology using medium energetic backscattered ions detected by means of a semiconductor radiation detector instead of an ESA. The study of medium energy ion scattering (MEIS) has been performed using the 40 keV industrial ion implanter established at GNS Sciences remodelled with supplementary high voltage insulation for the ion source in order to apply voltages up to 45 kV, extra apertures installed in the beamline and sample chamber in order to set the beam diameter accurately, and a semiconductor radiation detector. For measurement purposes a beam of positive charged helium ions accelerated to an energy of about 80 keV has been used impinging onto target surfaces of lead implanted into silicon (PbSi), scandium implanted into aluminium (ScAl), aluminium foil (Al) and glassy carbon (C). First results show that it is possible to use the upgraded industrial implanter for medium energy ion scattering. The beam of 4 He 2+ with an energy up to 88 keV has been focussed to 1 mm in diameter. The 5 nA ion beam hit the samples under 2 x 10 -8 mbar. The results using the surface barrier detector show scattering events from the samples. Cooling of the detector to liquid nitrogen temperatures reduced the electronic noise in the backscattering spectrum close to zero. A

  15. TU-AB-BRC-10: Modeling of Radiotherapy Linac Source Terms Using ARCHER Monte Carlo Code: Performance Comparison of GPU and MIC Computing Accelerators

    International Nuclear Information System (INIS)

    Liu, T; Lin, H; Xu, X; Su, L; Shi, C; Tang, X; Bednarz, B

    2016-01-01

    Purpose: (1) To perform phase space (PS) based source modeling for Tomotherapy and Varian TrueBeam 6 MV Linacs, (2) to examine the accuracy and performance of the ARCHER Monte Carlo code on a heterogeneous computing platform with Many Integrated Core coprocessors (MIC, aka Xeon Phi) and GPUs, and (3) to explore the software micro-optimization methods. Methods: The patient-specific source of Tomotherapy and Varian TrueBeam Linacs was modeled using the PS approach. For the helical Tomotherapy case, the PS data were calculated in our previous study (Su et al. 2014 41(7) Medical Physics). For the single-view Varian TrueBeam case, we analytically derived them from the raw patient-independent PS data in IAEA’s database, partial geometry information of the jaw and MLC as well as the fluence map. The phantom was generated from DICOM images. The Monte Carlo simulation was performed by ARCHER-MIC and GPU codes, which were benchmarked against a modified parallel DPM code. Software micro-optimization was systematically conducted, and was focused on SIMD vectorization of tight for-loops and data prefetch, with the ultimate goal of increasing 512-bit register utilization and reducing memory access latency. Results: Dose calculation was performed for two clinical cases, a Tomotherapy-based prostate cancer treatment and a TrueBeam-based left breast treatment. ARCHER was verified against the DPM code. The statistical uncertainty of the dose to the PTV was less than 1%. Using double-precision, the total wall time of the multithreaded CPU code on a X5650 CPU was 339 seconds for the Tomotherapy case and 131 seconds for the TrueBeam, while on 3 5110P MICs it was reduced to 79 and 59 seconds, respectively. The single-precision GPU code on a K40 GPU took 45 seconds for the Tomotherapy dose calculation. Conclusion: We have extended ARCHER, the MIC and GPU-based Monte Carlo dose engine to Tomotherapy and Truebeam dose calculations.

  16. TU-AB-BRC-10: Modeling of Radiotherapy Linac Source Terms Using ARCHER Monte Carlo Code: Performance Comparison of GPU and MIC Computing Accelerators

    Energy Technology Data Exchange (ETDEWEB)

    Liu, T; Lin, H; Xu, X [Rensselaer Polytechnic Institute, Troy, NY (United States); Su, L [John Hopkins University, Baltimore, MD (United States); Shi, C [Saint Vincent Medical Center, Bridgeport, CT (United States); Tang, X [Memorial Sloan Kettering Cancer Center, West Harrison, NY (United States); Bednarz, B [University of Wisconsin, Madison, WI (United States)

    2016-06-15

    Purpose: (1) To perform phase space (PS) based source modeling for Tomotherapy and Varian TrueBeam 6 MV Linacs, (2) to examine the accuracy and performance of the ARCHER Monte Carlo code on a heterogeneous computing platform with Many Integrated Core coprocessors (MIC, aka Xeon Phi) and GPUs, and (3) to explore the software micro-optimization methods. Methods: The patient-specific source of Tomotherapy and Varian TrueBeam Linacs was modeled using the PS approach. For the helical Tomotherapy case, the PS data were calculated in our previous study (Su et al. 2014 41(7) Medical Physics). For the single-view Varian TrueBeam case, we analytically derived them from the raw patient-independent PS data in IAEA’s database, partial geometry information of the jaw and MLC as well as the fluence map. The phantom was generated from DICOM images. The Monte Carlo simulation was performed by ARCHER-MIC and GPU codes, which were benchmarked against a modified parallel DPM code. Software micro-optimization was systematically conducted, and was focused on SIMD vectorization of tight for-loops and data prefetch, with the ultimate goal of increasing 512-bit register utilization and reducing memory access latency. Results: Dose calculation was performed for two clinical cases, a Tomotherapy-based prostate cancer treatment and a TrueBeam-based left breast treatment. ARCHER was verified against the DPM code. The statistical uncertainty of the dose to the PTV was less than 1%. Using double-precision, the total wall time of the multithreaded CPU code on a X5650 CPU was 339 seconds for the Tomotherapy case and 131 seconds for the TrueBeam, while on 3 5110P MICs it was reduced to 79 and 59 seconds, respectively. The single-precision GPU code on a K40 GPU took 45 seconds for the Tomotherapy dose calculation. Conclusion: We have extended ARCHER, the MIC and GPU-based Monte Carlo dose engine to Tomotherapy and Truebeam dose calculations.

  17. Arquetipos iconográficos femeninos en el cómic y la animación japonesa para adolescentes masculinos

    OpenAIRE

    López Rodríguez, Francisco Javier; García Pacheco, Juan A.

    2011-01-01

    El cómic japonés (manga) y la animación japonesa (anime) son poderosas industrias culturales que, progresivamente, se han ido expandiendo internacionalmente. A medida que estas obras han ido llegando a los mercados occidentales, la atención de los investigadores se ha fijado en las particularidades expresivas, narrativas y culturales de estos productos. La investigación en género relacionada con el manga y el anime se ha centrado principalmente en las obras destinadas a un público femenino y,...

  18. Pathobiological implications of the expression of EGFR, pAkt, NF-κB and MIC-1 in prostate cancer stem cells and their progenies.

    Directory of Open Access Journals (Sweden)

    Murielle Mimeault

    Full Text Available The progression of prostate cancers (PCs to locally invasive, androgen-independent and metastatic disease states is generally associated with treatment resistance and disease relapse. The present study was undertaken to establish the possibility of using a combination of specific oncogenic products, including epidermal growth factor receptor (EGFR, pAkt, nuclear factor-kappaB (NF-κB and macrophage inhibitory cytokine-1 (MIC-1 as biomarkers and therapeutic targets for optimizing the management of patients with localized PC at earlier disease stages. The immunohistochemical and immunofluorescence data have revealed that the expression levels of EGFR, Ser(473-pAkt, NF-κB p65 and MIC-1 proteins were significantly enhanced in the same subset of 76 cases of prostatic adenocarcinoma specimens during the disease progression and these biomarkers were expressed in a small subpopulation of CD133(+ PC cells and the bulk tumor mass of CD133(- PC cells. Importantly, all of these biomarkers were also overexpressed in 80-100% of 30 PC metastasis bone tissue specimens. Moreover, the results have indicated that the EGF-EGFR signaling pathway can provide critical functions for the self-renewal of side population (SP cells endowed with stem cell-like features from highly invasive WPE1-NB26 cells. Of therapeutic interest, the targeting of EGFR, pAkt, NF-κB or MIC-1 was also effective at suppressing the basal and EGF-promoted prostasphere formation by SP WPE1-NB26 cells, inducing disintegration of SP cell-derived prostaspheres and decreasing the viability of SP and non-SP WPE1-NB26 cell fractions. Also, the targeting of these oncogenic products induced the caspase-dependent apoptosis in chemoresistant SP WPE1-NB26 cells and enhanced their sensibility to the cytotoxic effects induced by docetaxel. These findings suggest that the combined use of EGFR, pAkt, NF-κB and/or MIC-1 may represent promising strategies for improving the accuracy of current diagnostic and

  19. Perspectivas de la niñez adulta: El cómic como espacio de denuncia desde la marginalidad de sus personajes

    OpenAIRE

    Ana Merino

    2010-01-01

    Este artículo analiza la representación de la niñez en varios cómics iberoamericanos: Mafalda de Quino, Paracuellos de Carlos Jiménez y Socorro de Miguel Rep. En ellos se articula la infancia desde una perspectiva adulta y crítica con la sociedad mostrando una dimensión comprometida que interpela al lector. This article analyzes the representation of childhood in several Latin American comics: Mafalda by Quino, Paracuellos by Carlos Jiménez, and Socorro by Miguel Rep. In these comics, infancy...

  20. Perspectivas de la niñez adulta: el cómic como espacio de denuncia desde la marginalidad de sus personajes

    OpenAIRE

    Merino, Ana

    2010-01-01

    Este artículo analiza la representación de la niñez en varios cómics iberoamericanos: mafalda de quino, paracuellos de carlos jiménez y socorro de miguel rep. En ellos se articula la infancia desde una perspectiva adulta y crítica con la sociedad mostrand This article analyzes the representation of childhood in several latin american comics: mafalda by quino, paracuellos by carlos jiménez, and socorro by miguel rep. In these comics, infancy is articulated from an adult angle critical with ...

  1. Recovery in aluminium

    DEFF Research Database (Denmark)

    Gundlach, Carsten

    2006-01-01

    In the present thesis the development of a unique experimental method for volume characterisation of individual embedded crystallites down to a radius of 150 nm is presented. This method is applied to in-situ studies of recovery in aluminium. The method is an extension of 3DXRD microscopy, an X...... are represented as strings. To identify the strings a combination of a 5D connected component type algorithm and multi-peak fitting was found to be superior. The first use of the method was a study of recovery of a deformed aluminium alloy (AA1050). The aluminium alloy was deformed by cold rolling to a thickness...

  2. Orimulsion containment and recovery

    International Nuclear Information System (INIS)

    Sommerville, M.

    1999-01-01

    This paper focuses on the need for examination of Orimulsion fuel and its spill behaviour in the light of the anticipated increase in consumption of this fuel which comprises bitumen dispersed in water with addition of a small amount of surfactant. The behaviour and fate of Orimulsion at sea, and observations from experimental and sea trials are examined. The identification of spill control techniques, spill detection, the predictive modeling of the spill and response, sub-surface plume measurement, and containment and deflection are considered. Recovery of the bitumen produced from an Orimulsion spill, combined containment and recovery, dispersed Orimulsion, and beach cleaning are addressed. The properties of Orimulsion are tabulated. (UK)

  3. Recovery of vanadium oxide

    International Nuclear Information System (INIS)

    Bates, C.P.; Clark, N.E.

    1985-01-01

    This invention relates to the recovery of vanadium oxide from molten metal. The invention provides a method for recovering vanadium oxide from molten metal, which includes passing oxygen and at least one coolant gas or shroud into the molten metal by way of at least one elongate lance. The invention also provides an arrangement for the recovery of vanadium oxide from molten metal, which includes at least one elongate lance extending into the molten metal. The lance is provided with at least one elongate bore extending therethrough. Means are provided to allow at least oxygen and at least one coolant gas to pass through the lance and into the molten metal

  4. Ventilation with heat recovery

    DEFF Research Database (Denmark)

    Tommerup, Henrik M.; Svendsen, Svend

    2005-01-01

    This paper presents the experiences from the use of ventilation with heat recovery in several experimental single-family houses developed and built within the last four years to meet the new Danish energy requirements of 2005. Included are descriptions of the ventilation system components...... and the main functional demands as well as measurements of the thermal efficiency, electricity consumptions and building air tightness. The paper addresses the aspects of minimizing the heat loss from the duct system and the heat recovery unit (when placed in an unheated attic space) in order to obtain...

  5. JLAB Hurricane recovery

    International Nuclear Information System (INIS)

    A. Hutton; D. Arenius; J. Benesch; S. Chattopadhyay; E. F. Daly; O. Garza; R. Kazimi; R. Lauzi; L. Merminga; W. Merz; R. Nelson; W. Oren; M. Poelker; P. Powers; J. Preble; V. Ganni; C. R. Reece; R. Rimmer; M. Spata; S. Suhring

    2004-01-01

    Hurricane Isabel, originally a Category 5 storm, arrived at Jefferson Lab on September 18, 2003 with winds of only 75 mph, creating little direct damage to the infrastructure. However, electric power was lost for four days allowing the superconducting cryomodules to warm up and causing a total loss of the liquid helium. The subsequent recovery of the cryomodules and the impact of the considerable amount of opportunistic preventive maintenance provides important lessons for all accelerator complexes, not only those with superconducting elements. The details of how the recovery process was structured and the resulting improvement in accelerator availability will be discussed in detail

  6. La representación icónica y narrativa de la mujer en el cómic japonés masculino: el shounen manga y el horror manga

    Directory of Open Access Journals (Sweden)

    Juan A. García Pacheco

    2012-06-01

    Full Text Available El cómic japonés (Manga es un importante medio de comunicación en su país de origen y, gracias su progresiva expansión internacional, en muchos países occidentales. Gran parte de los estudios de género realizados sobre el cómic japonés se han centrado en las obras dirigidas a una audiencia femenina. El presente artículo analiza un área menos abordada como es la representación de la mujer en el cómic japonés masculino, la cual es estudiada a través de dos métodos de análisis (iconográfico y narrativo en dos tipos de cómics bien definidos en sus características como son el cómic de acción y aventura para adolescentes masculinos (shounen manga y el cómic de terror (horror manga para el público adulto.

  7. Medium Effects on Minimum Inhibitory Concentrations of Nylon-3 Polymers against E. coli

    Science.gov (United States)

    Choi, Heejun; Chakraborty, Saswata; Liu, Runhui; Gellman, Samuel H.; Weisshaar, James C.

    2014-01-01

    Minimum inhibitory concentrations (MICs) against E. coli were measured for three nylon-3 polymers using Luria-Bertani broth (LB), brain-heart infusion broth (BHI), and a chemically defined complete medium (EZRDM). The polymers differ in the ratio of hydrophobic to cationic subunits. The cationic homopolymer is inert against E. coli in BHI and LB, but becomes highly potent in EZRDM. A mixed hydrophobic/cationic polymer with a hydrophobic t-butylbenzoyl group at its N-terminus is effective in BHI, but becomes more effective in EZRDM. Supplementation of EZRDM with the tryptic digest of casein (often found in LB) recapitulates the LB and BHI behavior. Additional evidence suggests that polyanionic peptides present in LB and BHI may form electrostatic complexes with cationic polymers, decreasing activity by diminishing binding to the anionic lipopolysaccharide layer of E. coli. In contrast, two natural antimicrobial peptides show no medium effects. Thus, the use of a chemically defined medium helps to reveal factors that influence antimicrobial potency of cationic polymers and functional differences between these polymers and evolved antimicrobial peptides. PMID:25153714

  8. Sticking to the “Factual.” Man Ray’s Le Retour à la raison (1923, Marcel Duchamp’s Anémic cinéma (1924–26 and Peter Tscherkassky’s Dream Work (2001

    Directory of Open Access Journals (Sweden)

    Gabriele Jutz

    2014-07-01

    Full Text Available The present article seeks to show that, for the Dadaists, film was an unsatisfying medium because as a technically reproduced artifact it counteracted Dada’s sense of immediacy. The focus of my text revolves around the notion of “facticity” inspired by Wieland Herzfelde, for whom Dada represented a reaction to all attempts at disavowing the “factual.” Manifestations of Dada, such as the readymade, live performance, collage, photomontage and not least the photogram, attest to a radically new understanding of realism in art, adhering to an “anti-mimetic concept of realism” (Elsaesser. As I will argue, Dada did not capitulate to film, but made a ‘compromise,’ by exploring different strategies to reinsert the “factual“ into this medium of reproduction. This could be done by (1 turning a screening into a live performance, (2 eliciting a bodily reaction in the spectator, (3 experimenting with hand-made, camera-less devices of film making, and (4 calling to mind the material existence of the cinematic apparatus. What these strategies have in common is to minimalize (although not necessarily to abolish the distance between “reality” and its representation in order to maintain film’s initial tactility, as described by Walter Benjamin in “The Work of Art in the Age of Mechanical Reproduction.” Man Ray’s Le Retour à la raison (1923 and Marcel Duchamp’s Anémic cinéma (1924–26 are prototypes of the Dadaist ‘compromise.’ A similar impetus can be found in a more recent example, Dream Work (2001, the third part of Peter Tscherkassky’s CinemaScope-Trilogy, which explicitly refers to the early days of French experimental film. What these three films, despite their differences, have in common, is to privilege a certain immediacy (be it during the moment of production or during the moment of reception and to include an element of tactility, usually absent from cinematic works.

  9. Electrodeposition of ruthenium, rhodium and palladium from nitric acid and ionic liquid media: Recovery and surface morphology of the deposits

    Energy Technology Data Exchange (ETDEWEB)

    Jayakumar, M.; Venkatesan, K.A.; Sudha, R. [Fuel Chemistry Division, Indira Gandhi Centre for Atomic Research, Kalpakkam, Tamil Nadu 603102 (India); Srinivasan, T.G., E-mail: tgs@igcar.gov.com [Fuel Chemistry Division, Indira Gandhi Centre for Atomic Research, Kalpakkam, Tamil Nadu 603102 (India); Vasudeva Rao, P.R. [Fuel Chemistry Division, Indira Gandhi Centre for Atomic Research, Kalpakkam, Tamil Nadu 603102 (India)

    2011-07-15

    Research highlights: {yields} Platinum group metals are man-made noble metals. {yields} Electrochemical recovery of fission platinoids. {yields} Recovery from nitric acid medium. {yields} Recovery from ionic liquid medium. {yields} Platinoids with exotic surface morphologies. - Abstract: Electrodeposition is a promising technique for the recovery of platinum group metals with unique surface morphologies. The electrodeposition of palladium, ruthenium and rhodium from aqueous nitric acid, and non-aqueous 1-butyl-3-methylimidazolium chloride ionic liquid medium was studied at stainless steel electrode. The surface morphology and elemental composition of the resultant deposit were probed by scanning electron microscopy (SEM) and energy dispersive X-ray (EDS) analysis. Deposits with diverse surface morphologies and metal compositions were obtained by varying the composition of the electrolytic medium and applied potential. The results demonstrate the possibility of tailoring the morphologies of PGMs by controlling the composition and potential needed for electrodeposition.

  10. Behaviour Recovery. Second Edition

    Science.gov (United States)

    Rogers, Bill

    2004-01-01

    This second edition of Behaviour Recovery puts emphasis on teaching behaviour concerning children with emotional and behavioural disorders (EBD). These children have many factors in their lives that affect their behaviour over which schools have limited control. This book acknowledges the challenge and explores the practical realities, options and…

  11. Oil spill recovery technology

    International Nuclear Information System (INIS)

    Nash, J.; Cooper, W.; Nee, V.; Nigim, H.

    1992-01-01

    Current deficiencies in oil spill cleanup processes have resulted in research and development of new cleanup technologies at the University of Notre Dame. Emphasis on reducing, reusing and recycling equipment and waste at a cleanup site has prompted advances in oil recovery technology as well as improvement in sorbent materials. (author)

  12. Heat Recovery System

    Science.gov (United States)

    1984-01-01

    Ball Metal's design of ducting and controls for series of roof top heat exchangers was inspired by Tech Briefs. Heat exchangers are installed on eight press and coating lines used to decorate sheet metal. The heat recovery system provides an estimated energy savings of more than $250,000 per year.

  13. Cost Recovery Through Depreciation.

    Science.gov (United States)

    Forrester, Robert T.; Wesolowski, Leonard V.

    1983-01-01

    The approach of adopting depreciation rather than use allowance in order to recover more accurately the cost of college buildings and equipment used on federal projects is considered. It is suggested that depreciation will offer most colleges and universities a higher annual recovery rate, and an opportunity for better facilities planning. For…

  14. Sludge recovery apparatus

    International Nuclear Information System (INIS)

    Marmo, A.R.

    1979-01-01

    Sludge recovery machine comprising a hollow centrifuge, a vertical pipe for feeding in a liquid containing sludge and a sliding rake pressing against the internal wall of the centrifuge to dislodge and move the sludge, a power drive for spinning the centrifuge at high speed and a rotating drying table to take the sludge and dry it [fr

  15. Collegiate Recovery Programs

    Science.gov (United States)

    Harris, Kitty S.; Kimball, Thomas G.; Casiraghi, Ann M.; Maison, Sara J.

    2014-01-01

    More than ever, people are seeking substance use disorder treatment during the adolescent and young adult stages of development. Developmentally, many of these young adults new to recovery are in the process of making career decisions that may require attendance at a college or university. However, the collegiate environment is not conducive to a…

  16. Accretion from an inhomogeneous medium

    International Nuclear Information System (INIS)

    Livio, M.; Soker, N.; Koo, M. de; Savonije, G.J.

    1986-01-01

    The problem of accretion by a compact object from an inhomogeneous medium is studied in the general γnot=1 case. The mass accretion rate is found to decrease with increasing γ. The rate of accretion of angular momentum is found to be significantly lower than the rate at which angular momentum is deposited into the Bondi-Hoyle, symmetrical, accretion cylinder. The consequences of the results are studied for the cases of neutron stars accreting from the winds of early-type companions and white dwarfs and main-sequence stars accreting from winds of cool giants. (author)

  17. A Heterogeneous Medium Analytical Benchmark

    International Nuclear Information System (INIS)

    Ganapol, B.D.

    1999-01-01

    A benchmark, called benchmark BLUE, has been developed for one-group neutral particle (neutron or photon) transport in a one-dimensional sub-critical heterogeneous plane parallel medium with surface illumination. General anisotropic scattering is accommodated through the Green's Function Method (GFM). Numerical Fourier transform inversion is used to generate the required Green's functions which are kernels to coupled integral equations that give the exiting angular fluxes. The interior scalar flux is then obtained through quadrature. A compound iterative procedure for quadrature order and slab surface source convergence provides highly accurate benchmark qualities (4- to 5- places of accuracy) results

  18. Charmed hadrons in nuclear medium

    International Nuclear Information System (INIS)

    Tolos, L.; Gamermann, D.; Molina, R.; Nieves, J.; Oset, E.; Garcia-Recio, C.; Ramos, A.

    2010-01-01

    We study the properties of charmed hadrons in dense matter within a coupled-channel approach which accounts for Pauli blocking effects and meson self-energies in a self-consistent manner. We analyze the behaviour in this dense environment of dynamically-generated baryonic resonances as well as the open-charm meson spectral functions. We discuss the implications of the in-medium properties of open-charm mesons on the D s0 (2317) and the predicted X(3700) scalar resonances. (authors)

  19. Development of brachytherapy medium doserate

    International Nuclear Information System (INIS)

    Atang Susila; Ari Satmoko; Ahmad Rifai; Kristiyanti

    2010-01-01

    Brachytherapy has proven to be an effective treatment for different types of cancers and it become a common treatment modality in most radiotherapy clinics. PRPN has had experience in development of Low Dose Rate Brachytherapy for cervix cancer treatment. However the treatment process using LDR device needs 5 hours in time that the patient feel uncomfort. Therefore PRPN develops Medium Dose Rate Brachytherapy with radiation activity not more than 5 Currie. The project is divided into two stages. Purchasing of TPS software and TDS design are held in 2010, and the construction will be in 2011. (author)

  20. Application of Intel Many Integrated Core (MIC) architecture to the Yonsei University planetary boundary layer scheme in Weather Research and Forecasting model

    Science.gov (United States)

    Huang, Melin; Huang, Bormin; Huang, Allen H.

    2014-10-01

    The Weather Research and Forecasting (WRF) model provided operational services worldwide in many areas and has linked to our daily activity, in particular during severe weather events. The scheme of Yonsei University (YSU) is one of planetary boundary layer (PBL) models in WRF. The PBL is responsible for vertical sub-grid-scale fluxes due to eddy transports in the whole atmospheric column, determines the flux profiles within the well-mixed boundary layer and the stable layer, and thus provide atmospheric tendencies of temperature, moisture (including clouds), and horizontal momentum in the entire atmospheric column. The YSU scheme is very suitable for massively parallel computation as there are no interactions among horizontal grid points. To accelerate the computation process of the YSU scheme, we employ Intel Many Integrated Core (MIC) Architecture as it is a multiprocessor computer structure with merits of efficient parallelization and vectorization essentials. Our results show that the MIC-based optimization improved the performance of the first version of multi-threaded code on Xeon Phi 5110P by a factor of 2.4x. Furthermore, the same CPU-based optimizations improved the performance on Intel Xeon E5-2603 by a factor of 1.6x as compared to the first version of multi-threaded code.

  1. Brief report: the Utrecht-Management of Identity Commitments Scale (U-MICS): gender and age measurement invariance and convergent validity of the Turkish version.

    Science.gov (United States)

    Morsunbul, Umit; Crocetti, Elisabetta; Cok, Figen; Meeus, Wim

    2014-08-01

    The purpose of this study was to evaluate the factor structure and convergent validity of the Turkish version of the Utrecht-Management of Identity Commitments Scale (U-MICS). Participants were 1201 (59.6% females) youth aged between 12 and 24 years (M(age) = 17.53 years, SD(age) = 3.25). Results indicated that the three-factor model consisting of commitment, in-depth exploration, and reconsideration of commitment provided a very good fit to the data and applied equally well to boys and girls as well as to three age groups (early adolescents, middle adolescents, and emerging adults). Significant relations between identity processes and self-concept clarity, personality, internalizing and externalizing problem behaviors, and parental relationships supported convergent validity. Thus, the Turkish version of U-MICS is a reliable tool for assessing identity in Turkish-speaking respondents. Copyright © 2014 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.

  2. Adaptation of the Utrecht-Management of Identity Commitments Scale (U-MICS) to the measurement of the parental identity domain.

    Science.gov (United States)

    Piotrowski, Konrad

    2018-04-01

    The present studies examined the psychometric properties of the Utrecht-Management of Identity Commitments Scale (U-MICS) adapted to the measurement of identity formation in the parental identity domain. As the parental identity domain has only been studied within the neo-Eriksonian approach to a very limited extent, the aim of these studies was to prepare a short, valid and reliable tool for the measurement of parental identity in order to fill this gap. The associations of commitment, in-depth exploration and reconsideration of commitment in the parental domain with well-being and with other identity constructs were analyzed. The results showed that parental identity formation is associated with mothers' satisfaction with life and trait anxiety and with identity formation in other areas as well. The initial results suggest that the adapted version of the U-MICS is a valid and reliable measure that can be used in future studies on parental identity formation. © 2017 The Author. Scandinavian Journal of Psychology published by Scandinavian Psychological Associations and John Wiley & Sons Ltd.

  3. Short forms of the Utrecht-Management of Identity Commitments Scale (U-MICS) with the domains of job, romantic relationship, and region.

    Science.gov (United States)

    Schubach, Elisabeth; Zimmermann, Julia; Noack, Peter; Neyer, Franz J

    2017-01-01

    The U-MICS is a self-report questionnaire designed to assess the identity dimensions from a domain-specific perspective. The present study reports on the development of a short-form version for the domains of job and romantic relationship in young adults from Germany and extends this scale to include the domain of region (n Sample1  = 95, 84% female, mean age 22.45 years; n Sample2  = 1,795, 71% female, mean age 24.53 years). We found the short form to possess adequate psychometric properties and to demonstrate a factor structure congruent to the long-form version. Regarding validity, the small correlations across domains within dimensions support a domain-specific approach to identity. The associations between the different identity domains with personality traits are similar, indicating a consistent pattern of convergent validity for all domains. We conclude that "region" provides a valuable complement to the established domains that can all be reliably assessed with the U-MICS-Short Form. Copyright © 2016 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.

  4. SOLUTION FOR ICHTHYOFAUNA MIGRATION UPSTREAM- DOWNSTREAM OF THE TWO SPILLWAYS LOCATED NEAR MANASTUR DAM ON THE SOMESUL MIC RIVER IN THE CLUJ NAPOCA CITY (ROMÂNIA

    Directory of Open Access Journals (Sweden)

    Razvan VOICU

    2015-06-01

    Full Text Available Longitudinal connectivity represent the way in which organisms move the energy and material exchanges located throughout the water. Fragmentation the longitudinal connectivity of watercourses caused by dams or other hydrotechnical constructions represent a major impact on sediment transport, hydrological regime, downstream moving and biota migration. The hydromorphological elements (river continuity, as well as chemical, biological, physicochemical elements characterize the ecological status of rivers.Migratory fish species: nase (Chondrostoma nasus - protected by Bern Convention - Appendix III and barbel (Barbus barbus - rare species, protected Habitats Directive (Annex V, annex 4A of Low nr.462 and Red List of RBDD are blocked but the Hydrotechnical constructions (discharge sills, dams etc located across the watercourse Somes Mic River. One of the important think of this system is the gravitational fall of water. This solution will lead to the restoration of the longitudinal connection of the Someşul Mic River in the Manastur neighborhood. România is part of the European Union and it has the obligation to implement the provisions of the Water Framework Directive 2000/60/EC, transposed into Romanian legislation by the Water Law 107/1996 as supplemented and amended (Act 310/2004. This engineering solution for fish fauna migration upstream – downstream of the spillways supports the Water Framework Directive 2000/60/EC, transposed into Romanian legislation by the Water Law 107/1996 as supplemented and amended (Act 310/2004.

  5. Liberalismo vs. neo-fascismo: perspectiva sociosemiótica y análisis político del cómic Guerra Civil

    Directory of Open Access Journals (Sweden)

    Liber Daniel Cuñarro Conde

    2014-01-01

    Full Text Available La presente investigación analiza desde una perspectiva sociosemiótica y política algunos de los aspectos más relevantes del cómic Guerra Civil de Marvel como expresión de los eventos del 11 de septiembre de 2001 en los Estados Unidos de América. Dicho texto se examina desde los enfoques postulados por Greimas (1966 y Eco (1993. A tal efecto se ha seleccionado un corpus concreto, constituido por los siete ejemplares que representan la historia principal de la serie titulada Civil War, en su lenguaje original. Para lograr la comprensión del programa narrativo del cómic, este estudio proporciona el antetexto y la información pertinente para hacer posible una interpretación de los elementos políticos e ideológicos de la Guerra Civil de Marvel, su relación con la representación alegórica de los hechos históricos y su textualización como expresión simbólica de la sociedad contemporánea.

  6. Liberalismo vs. neo-fascismo: perspectiva sociosemiótica y análisis político del cómic Guerra Civil

    Directory of Open Access Journals (Sweden)

    Liber Daniel Cuñarro Conde

    2014-01-01

    Full Text Available La presente investigación analiza desde una perspectiva socios emiótica y política algunos de los aspectos más relevantes del cómic Guerra Civil de Marvel como expresión de los eventos del 11 de septiembre de 2001 en los Estados Unidos de América. Dicho texto se examina desde los enfoques postulados por Greimas (1966 y Eco (1993. A tal efecto se ha seleccionado un corpus concreto, constituido por los siete ejemplares que representan la historia principal de la serie titulada Civil War, en su lenguaje original. Para lograr la comprensión del programa narrativo del cómic, este estudio proporciona el ante texto y la información pertinente para hacer posible una interpretación de los elementos políticos e ideológicos de la Guerra Civil de Marvel, su relación con la representación alegórica de los hechos históricos y su textualización como expresión simbólica de la sociedad contemporánea.

  7. Thermoelectric Waste Heat Recovery Program for Passenger Vehicles

    Energy Technology Data Exchange (ETDEWEB)

    Jovovic, Vladimir [Gentherm Incorporated, Azusa, CA (United States)

    2015-12-31

    Gentherm began work in October 2011 to develop a Thermoelectric Waste Energy Recovery System for passenger vehicle applications. Partners in this program were BMW and Tenneco. Tenneco, in the role of TIER 1 supplier, developed the system-level packaging of the thermoelectric power generator. As the OEM, BMW Group demonstrated the TEG system in their vehicle in the final program phase. Gentherm demonstrated the performance of the TEG in medium duty and heavy duty vehicles. Technology developed and demonstrated in this program showed potential to reduce fuel consumption in medium and heavy duty vehicles. In light duty vehicles it showed more modest potential.

  8. Medium modification of fragmentation functions

    International Nuclear Information System (INIS)

    Nezza, Pasquale Di

    2007-01-01

    Deep Inelastic Scattering is the cleanest process to investigate the space-time evolution of the hadronization. This was studied by the influence of the nuclear medium on lepto-production of hadrons at the Hermes experiment at DESY in semi-inclusive DIS of 27.6 GeV positrons off deuterium, nitrogen, krypton and xenon targets. The differential multiplicity for heavy targets relative to that of deuterium has been measured for the first time for various identified hadrons (φ + , φ - , φ 0 , k + , k - , p and anti-p) as a function of the virtual photon energy ?, the fraction z of this energy transferred to the hadron, and the hadron transverse momentum squared p 2 t . The distribution of the hadron transverse momentum is broadened towards high p 2 t in the nuclear medium, in a manner resembling the Cronin effect observed in collisions of heavy ions and protons with nuclei. The pt -broadening results give also important information about the pre-hadron formation time. Moreover, by studying the hadron attenuation of the leading and sub-leading hadrons, we report, for the first time, the possibility to better understand the hadron absorption and the energy loss contributions to the attenuation mechanism. (Author)

  9. Gravitational lensing in plasmic medium

    Energy Technology Data Exchange (ETDEWEB)

    Bisnovatyi-Kogan, G. S., E-mail: gkogan@iki.rssi.ru; Tsupko, O. Yu., E-mail: tsupko@iki.rssi.ru [Russian Academy of Sciences, Space Research Institute (Russian Federation)

    2015-07-15

    The influence of plasma on different effects of gravitational lensing is reviewed. Using the Hamiltonian approach for geometrical optics in a medium in the presence of gravity, an exact formula for the photon deflection angle by a black hole (or another body with a Schwarzschild metric) embedded in plasma with a spherically symmetric density distribution is derived. The deflection angle in this case is determined by the mutual combination of different factors: gravity, dispersion, and refraction. While the effects of deflection by the gravity in vacuum and the refractive deflection in a nonhomogeneous medium are well known, the new effect is that, in the case of a homogeneous plasma, in the absence of refractive deflection, the gravitational deflection differs from the vacuum deflection and depends on the photon frequency. In the presence of a plasma nonhomogeneity, the chromatic refractive deflection also occurs, so the presence of plasma always makes gravitational lensing chromatic. In particular, the presence of plasma leads to different angular positions of the same image if it is observed at different wavelengths. It is discussed in detail how to apply the presented formulas for the calculation of the deflection angle in different situations. Gravitational lensing in plasma beyond the weak deflection approximation is also considered.

  10. Unsaturated medium hydrocarbons pollution evaluation

    International Nuclear Information System (INIS)

    Di Luise, G.

    1991-01-01

    When the so called porous unsaturated medium, that's the vertical subsoil section between both the ground and water-table level, is interested by a hydrocarbons spill, the problem to evaluate the pollution becomes difficult: considering, essentially, the natural coexistence in it of two fluids, air and water, and the interactions between them. This paper reports that the problems tend to increase when a third fluid, the pollutant, immiscible with water, is introduced into the medium: a three-phases flow, which presents several analogies with the flow conditions present in an oil-reservoir, will be established. In such a situation, it would be very useful to handle the matter by the commonly used parameters in the oil reservoirs studies such as: residual saturation, relative permeability, phases mobility, to derive a first semiquantitative estimation of the pollution. The subsoil pollution form hydrocarbons agents is one of the worldwide more diffused causes of contamination: such events are generally referable to two main effects: accidental (oil pipeline breakdowns, e.g.), and continuous (underground tanks breaks, industrial plants leakages, e.g.)

  11. Is the intercloud medium pervasive

    International Nuclear Information System (INIS)

    Heiles, C.

    1980-01-01

    We consider the pervasiveness of the ''not strongly absorbing'' (NSA) H I gas, which is the intercloud medium in steady state theories of the interstellar medium. We study the question by analyzing wide emission components in nearby gas, and the absence of absorption components in distant gas. We conclude that the NSA material is deficient in the immediately local solar vicinity. In nearby regions it contains 38% of the interstellar H I; it is generally pervasive and often has internal motions which greatly increase its velocity dispersion above the 5 km s -1 minimum value. It contains large holes, perhaps ranging up to 400 pc diameter, which probably occupy 10--20% of the volume. In distant regions the NSA material seems to be pervasive outside 8 kpc galactic radius. For galactic radii between 8 and 10 kpc its thickness agrees with previous determinations of 370 pc for nearby regions. Outside 10 kpc the thickness increases dramatically. Inside 8 kpc there are no data

  12. How Does the Medium Affect the Message?

    Science.gov (United States)

    Dommermuth, William P.

    1974-01-01

    This experimental comparison of the advertising effectiveness of television, movies, radio, and print finds no support for McLuhan's idea that television is a "cool" medium and movies are a "hot" medium. (RB)

  13. A differential medium for the enumeration of the spoilage yeast Zygosaccharomyces bailii in wine.

    Science.gov (United States)

    Schuller, D; Côrte-Real, M; Leão, C

    2000-11-01

    A collection of yeasts, isolated mostly from spoiled wines, was used in order to develop a differential medium for Zygosaccharomyces bailii. The 118 selected strains of 21 species differed in their origin and resistance to preservatives and belonged to the genera Pichia, Torulaspora, Dekkera, Debaryomyces, Saccharomycodes, Issatchenkia, Kluyveromyces, Kloeckera, Lodderomyces, Schizosaccharomyces, Rhodotorula, Saccharomyces, and Zygosaccharomyces. The design of the culture medium was based on the different ability of the various yeast species to grow in a mineral medium with glucose and formic acid (mixed-substrate medium) as the only carbon and energy sources and supplemented with an acid-base indicator. By manipulating the concentration of the acid and the sugar it was possible to select conditions where only Z. bailii strains gave rise to alkalinization, associated with a color change of the medium (positive response). The final composition of the mixed medium was adjusted as a compromise between the percentage of recovery and selectivity for Z. bailii. This was accomplished by the use of pure or mixed cultures of the yeast strains and applying the membrane filtration methodology. The microbiological analysis of two samples of contaminated Vinho Verde showed that the new medium can be considered as a differential medium to distinguish Z. bailii from other contaminating yeasts, having potential application in the microbiological control of wines and probably other beverages and foods.

  14. 27 CFR 19.914 - Medium plants.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Medium plants. 19.914... OF THE TREASURY LIQUORS DISTILLED SPIRITS PLANTS Distilled Spirits For Fuel Use Permits § 19.914 Medium plants. Any person wishing to establish a medium plant shall make application for and obtain in...

  15. Mapping of moveout in a TTI medium

    KAUST Repository

    Stovas, A.; Alkhalifah, Tariq Ali

    2012-01-01

    To compute moveout in a transversely isotropic medium with tilted symmetry axis is a very complicated problem. We propose to split this problem into two parts. First, to compute the moveout in a corresponding VTI medium. Second, to map the computed moveout to a TTI medium.

  16. Disaster Debris Recovery Database - Landfills

    Data.gov (United States)

    U.S. Environmental Protection Agency — The US EPA Disaster Debris Recovery Database (DDRD) promotes the proper recovery, recycling, and disposal of disaster debris for emergency responders at the federal,...

  17. A Bridge to Recovery

    Directory of Open Access Journals (Sweden)

    Rebecca M. Loya

    2015-02-01

    Full Text Available Sexual violence can trigger adverse economic events for survivors, including increased expenses and decreased earnings. Using interview data, this exploratory study examines how access to assets (liquid assets, familial financial assistance, and homeownership affects survivors’ economic well-being during recovery. In keeping with asset theory, liquid assets and familial assistance can help offset post-assault expenses and facilitate access to services. Homeownership, meanwhile, appears to have mixed effects on survivors’ economic well-being. These findings suggest that the economic costs of sexual violence can burden survivors with fewer financial resources more heavily than those who own significant assets. As such, these findings shift the focus toward a dimension of inequality in recovery from sexual violence that is often overlooked in research and that may have implications for public policy and victim services.

  18. Recovery of uranium values

    International Nuclear Information System (INIS)

    Rowden, G.A.

    1982-01-01

    A process is provided for the recovery of uranium from an organic extractant phase containing an amine. The extractant phase is contacted in a number of mixing stages with an acidic aqueous stripping phase containing sulphate ions, and the phases are passed together through a series of mixing stages while maintaining a dispersion of droplets of one phase in the other. Uranium is precipitated from the final stage by raising the pH. An apparatus having several mixing chambers is described

  19. Sludge recovery apparatus

    International Nuclear Information System (INIS)

    Marmo, A.R.

    1979-01-01

    An improved design of a sludge recovery apparatus used in the fabrication of nuclear fuel is described. This apparatus provides for automatic separation of sludge from the grinder coolant, drying of the sludge into a flowable powder and transfer of the dry powder to a salvage container. It can be constructed to comply with criticality-safe-geometry requirements and to obviate need for operating personnel in its immediate vicinity. (UK)

  20. Recovery From Comorbidity

    Directory of Open Access Journals (Sweden)

    Mathew Carter

    2013-11-01

    Full Text Available Comorbidity among mood, anxiety, and alcohol disorders is common and burdensome, affecting individuals, families, and public health. A systematic and integrative review of the literature across disciplines and research methodologies was performed. Supradisciplinary approaches were applied to the review and the ensuing critical appraisal. Definitions, measurement, and estimation are controversial and inconstant. Recovery from comorbidity cannot be easily extricated from a sociocultural milieu. Methodological challenges in quantitative and qualitative research and across disciplines are many and are discussed. The evidence supporting current treatments is sparse and short-term, and modalities operating in isolation typically fail. People easily fall into the cracks between mental health and addiction services. Clinicians feel untrained and consumers bear the brunt of this: Judgmental and moralistic interactions persist and comorbidity is unrecognized in high-risk populations. Competing historical paradigms of mental illness and addiction present a barrier to progress and reductionism is an impediment to care and an obstacle to the integration and interpretation of research. What matters to consumers is challenging to quantify but worth considering: Finding employment, safe housing, and meaning are crucial to recovery. Complex social networks and peer support in recovery are important but poorly understood. The focus on modalities of limited evidence or generalizability persists in literature and practice. We need to consider different combinations of comorbidity, transitions as opposed to dichotomies of use or illness, and explore the long-term view and emic perspectives.

  1. Medium-size nuclear plants

    International Nuclear Information System (INIS)

    Vogelweith, L.; Lavergne, J.C.; Martinot, G.; Weiss, A.

    1977-01-01

    CEA (TECHNICATOME) has developed a range of pressurized water reactors of the type ''CAS compact'' which are adapted to civil ship propulsion, or to electric power production, combined possibly with heat production, up to outputs equivalent to 125 MWe. Nuclear plants equipped with these reactors are suitable to medium-size electric networks. Among the possible realizations, two types of plants are mentioned as examples: 1) Floating electron-nuclear plants; and 2) Combined electric power and desalting plants. The report describes the design characteristics of the different parts of a 125 MWe unit floating electro-nuclear plant: nuclear steam system CAS 3 G, power generating plant, floating platform for the whole plant. The report gives attention to the different possibilities according to site conditions (the plant can be kept floating, in a natural or artificial basin, it can be put aground, ...) and to safety and environment factors. Such unit can be used in places where there is a growing demand in electric power and fresh water. The report describes how the reactor, the power generating plant and multiflash distillation units of an electric power-desalting plant can be combined: choice of the ratio water output/electric power output, thermal cycle combination, choice of the gain ratio, according to economic considerations, and to desired goal of water output. The report analyses also some technical options, such as: choice of the extraction point of steam used as heat supply of the desalting station (bleeding a condensation turbine, or recovering steam at the exhaust of a backpressure turbine), design making the system safe. Lastly, economic considerations are dealt with: combining the production of fresh water and electric power provides usually a much better energy balance and a lower cost for both products. Examples are given of some types of installations which combine medium-size reactors with fresh water stations yielding from 10000 to 120000 m 3 per day

  2. Autoras contemporáneas en la historieta española. Revisión de la etiqueta ‘cómic femenino’

    Directory of Open Access Journals (Sweden)

    Cortijo, Adela

    2011-09-01

    Full Text Available This article, whose title is so generic, does not intend to be an exhaustive and historiographic list of women authoring contemporary Spanish comics. A priori, the deficiencies of the global label “woman comic” are questioned and the representative work of a group of draftswomen and scriptwriters is shown, since the 1980 decade (Madriz, El Cairo and El Víbora to nowadays publications: Laura Pérez-Vernetti, Ana Juan, Ana Miralles, Sonia Pulido and Clara- Tanit. These authors are linked by a generational bond and offer a series of sights, paintstrokes, subjects and diverse plastic styles. The woman production phenomenon is observed along with its reception in ad hoc-collections published by some publishing houses through retrospectives, symposium and exhibitions which are still alerting about the so needed visibility. At the same time, both the atraction and the tendency towards the drawing art and equally the links between comic made by women and the concept related to the author comic, literature and egotistic tales are studied too.

    Este artículo, de título tan genérico, no pretende ser un listado exhaustivo e historiográfico de autoras de historieta contemporánea española. En esta aproximación se cuestionan a priori las deficiencias de la etiqueta global de “cómic femenino”, y se muestra el trabajo representativo de una serie de dibujantes y guionistas mujeres, desde los años ochenta (desde Madriz, El Cairo y El Víbora hasta la actualidad: Laura Pérez-Vernetti, Ana Juan, Ana Miralles, Sonia Pulido y Clara-Tanit. Autoras que se hilvanan en un hilo generacional y que ofrecen una explosión de miradas, de trazos, temas y estilos plásticos distintos. Se observa el fenómeno de la producción femenina y su recepción a través de colecciones ad hoc de algunas casas de edición, de retrospectivas, coloquios y exposiciones, que siguen alertando de la necesidad de una visibilidad

  3. La imagen y el texto en Le Photographe: una reflexión sobre fotoperiodismo, cómics y traducción

    Directory of Open Access Journals (Sweden)

    Sabrina Moura Aragao

    2016-11-01

    Full Text Available Este trabajo analiza cómo se produce el conocimiento del otro, es decir, del extranjero, a partir de la imagen y del texto en la traducción al portugués de Brasil del cómic francés “Le Photographe”. La obra está compuesta por dibujos, de Emmanuel Guibert, y de fotografías realizadas por Didier Levèfre que narran el trabajo de los Médicos Sin Fronteras durante la guerra en Afganistán a mediados de los años 1980. La obra fue publicada por primera vez en Francia en 2003 y en Brasil en 2006. Le Photographe constituye un rico material para el análisis gracias a la simultaneidad de discursos: el periodístico y el del cómic, al mismo tiempo que también propicia una reflexión sobre el proceso de traducción, ya que la obra intenta representar una cultura extranjera – la afgana – para franceses (en el contexto original y para brasileños (en el contexto de la traducción, lo que produce distintas representaciones y forma identidades culturales sobre aquel pueblo en los dos contextos de lectura de la obra. De esta manera, en el transcurso de la lectura del original a la traducción se construyen distintos tipos de conocimiento. Cuando analizamos Le Photographe, que se vale de un discurso periodístico y documental con las fotografías y la narración de los hechos de la guerra, nos vemos ante la construcción de “realidades”, y el periodismo tiene, para el sentido común, el poder de mostrar lo “real”. Nos interesa, entonces, investigar y discutir la formación de representaciones de la alteridad y de la “realidad” en el ámbito de los estudios de la traducción de cómics, observando la relación entre imagen y texto propio de este lenguaje y de qué manera el texto original y el traducido contribuyen, o no, para la formación de nuevas identidades culturales acerca del pueblo afgano.

  4. Tattoo: a multifaceted medium of communication

    Directory of Open Access Journals (Sweden)

    Christian Wymann

    2010-11-01

    Full Text Available This article suggests the systems theoretical distinction of form/medium as a useful tool for distinguishing social phenomena that might look as if they stem from the same process. This is shown to be the case for the tattoo and tattooing. The tattoo is conceived as a medium of communication through which different forms of communication emerge. Tattooing is one of these forms of communication that shapes the medium in a particular way. The current article sheds a special light on its intricate, communicational constellation, for which the concept of parallax is suggested. Law, medicine and cosmetics as other forms of communication use the medium of tattoo in their own way as well. The form/medium distinction allows us to grasp these different forms of communication, while it shows that they share the tattoo as medium. The article’s ultimate goal is to illustrate that the tattoo figures as a multifaceted medium of communication.

  5. Postirradiation recovery dependent on the uvr-1 Locus in Bacillus subtilis

    International Nuclear Information System (INIS)

    Hadden, C.T.

    1976-01-01

    A mutant (uvr-1) of Bacillus subtilis that is deficient in excision of ultraviolet (uv)-induced pyrimidine dimers from deoxyribonucleic acid (DNA) shows a marked increase in ability to survive uv irradiation when plated on amino acid-supplemented agar medium compared with its survival ability when plated on nutrient agar. Since the extent of killing depends on the richness of the plating medium, the effect is considered to be one of growth-dependent lethality. Irradiated stationary phase uvr-1 cells, incubated in liquid medium lacking amino acids required for growth, recover from this sensitivity to rich medium within 3 to 4 h after irradiation. Recovery is greatly reduced in the absence of glucose or in the presence of NaCN, athough it is not completely eliminated. Exponentially growing cells have a limited ability to recover from sensitivity to rich medium. Growth-dependent lethality can also occur in liquid medium. In nutrient broth the ability of irradiated stationary-phase uvr-1 cells to form colonies on defined agar medium decreases during postirradiation incubation, but treatment with chloramphenicol inhibits the loss of colony-forming ability. Recovery from sensitivity to rich media is inhibited by caffeine but not by 6-(p-hydroxyphenylazo)-uracil, an inhibitor of DNA replication. Alkaline sucrose gradient profiles show that conditions allowing recovery also favor maintaining intact DNA strands, whereas DNA strand breakage or degradation is associated with loss of viability

  6. Medium-Based Design: Extending a Medium to Create an Exploratory Learning Environment

    Science.gov (United States)

    Rick, Jochen; Lamberty, K. K.

    2005-01-01

    This article introduces "medium-based" design -- an approach to creating "exploratory learning environments" using the method of "extending a medium". First, the characteristics of exploratory learning environments and medium-based design are described and grounded in related work. Particular attention is given to "extending a medium" --…

  7. WASTE HEAT RECOVERY IN HEAT PUMP SYSTEMS: SOLUTION TO REDUCE GLOBAL WARMING

    Directory of Open Access Journals (Sweden)

    Y. Baradey

    2015-11-01

    Full Text Available Energy conversion technologies, where waste heat recovery systems are included, have received significant attention in recent years due to reasons that include depletion of fossil fuel, increasing oil prices, changes in climatic conditions, and global warming. For low temperature applications, there are many sources of thermal waste heat, and several recovery systems and potential useful applications have been proposed by researchers [1-4]. In addition, many types of equipment are used to recover waste thermal energy from different systems at low, medium, and high temperature applications, such as heat exchangers, waste heat recovery boiler, thermo-electric generators, and recuperators. In this paper, the focus is on waste heat recovery from air conditioners, and an efficient application of these energy resources. Integration of solar energy with heat pump technologies and major factors that affect the feasibility of heat recovery systems have been studied and reviewed as well. KEYWORDS: waste heat recovery; heat pump.

  8. Combinatorial effect of mutagenesis and medium component optimization on Bacillus amyloliquefaciens antifungal activity and efficacy in eradicating Botrytis cinerea.

    Science.gov (United States)

    Masmoudi, Fatma; Ben Khedher, Saoussen; Kamoun, Amel; Zouari, Nabil; Tounsi, Slim; Trigui, Mohamed

    2017-04-01

    This work is directed towards Bacillus amyloliquefaciens strain BLB371 metabolite production for biocontrol of fungal phytopathogens. In order to maximise antifungal metabolite production by this strain, two approaches were combined: random mutagenesis and medium component optimization. After three rounds of mutagenesis, a hyper active mutant, named M3-7, was obtained. It produces 7 fold more antifungal metabolites (1800AU/mL) than the wild strain in MC medium. A hybrid design was applied to optimise a new medium to enhance antifungal metabolite production by M3-7. The new optimized medium (35g/L of peptone, 32.5g/L of sucrose, 10.5g/L of yeast extract, 2.4g/L of KH 2 PO 4 , 1.3g/L of MgSO 4 and 23mg/L of MnSO 4 ) achieved 1.62 fold enhancement in antifungal compound production (3000AU/mL) by this mutant, compared to that achieved in MC medium. Therefore, combinatory effect of these two approaches (mutagenesis and medium component optimization) allowed 12 fold improvement in antifungal activity (from 250UA/mL to 3000UA/mL). This improvement was confirmed against several phytopathogenic fungi with an increase of MIC and MFC over than 50%. More interestingly, a total eradication of gray mold was obtained on tomato fruits infected by Botrytis cinerea and treated by M3-7, compared to those treated by BLB371. From the practical point of view, combining random mutagenesis and medium optimization could be considered as an excellent tool for obtaining promising biological products useful against phytopathogenic fungi. Copyright © 2017 Elsevier GmbH. All rights reserved.

  9. Competições e festivais na Grécia Pré-Helênica: as evidências minóico-micênicas

    OpenAIRE

    Ana Claudia Torralvo

    1997-01-01

    O que conhecemos das competições desportivas e dos festivais durante a Idade do Bronze na Grécia e no Egeu chegou até nós através das imagens representadas sobre os mais diversos suportes, como os afrescos, os relevos, a glíptica e outras manifestações da arte desse período. Neles percebemos algumas atividades físicas que podem caracterizar práticas desportivas: a luta corporal, praticada com luvas de couro, e a corrida, ambas comuns ao universo minóico-micênico. Já a tauromaquia ou salto do ...

  10. Attempt to validate breakpoint MIC values estimated from pharmacokinetic data obtained during oxolinic acid therapy of winter ulcer disease in Atlantic salmon ( Salmo salar )

    DEFF Research Database (Denmark)

    Coyne, R.; Bergh, Ø.; Samuelsen, O.

    2004-01-01

    Concentrations of oxolinic acid (OXA) were measured in the plasma, muscle, liver, and kidney of 48 Atlantic salmons (Salmo salar) 1 day after the end of an oral administration. OXA was administered over a period of 13 days to control an outbreak of winter ulcer disease in a commercial marine farm...... administration of OXA. A numerical description of the concentration of the antimicrobial agent achieved in therapy is necessary to determine the resistance or sensitivity of the bacteria involved in the infection. The degree of fish-to-fish variation in the concentrations of OXA, both within the healthy fish...... a useful parameter for describing the concentrations of agents achieved during therapy. The plasma data from this investigation were used to estimate clinically relevant breakpoint minimum inhibitory concentration (MIC) values. The validity of these breakpoint values was discussed with reference...

  11. Entornos tecnológicos en el discurso del cómic japonés: Akira, Dragon Head y Gantz

    Directory of Open Access Journals (Sweden)

    Manuel García Pérez

    2017-10-01

    Full Text Available El estudio de los contenidos de algunos cómics japoneses puede conducirnos al conocimiento de motivos, temas y estructuras recurrentes. El miedo al Apocalipsis y el recelo al milenarismo forman parte de la aventura literaria de muchas obras Manga donde el texto descriptivo y el texto cinematográfico operan juntos para producir esta clase de sensaciones que el receptor asume como premonitorias. Este recurso explica el miedo también a un entorno tecnológico que ha convertido las democracias reales en una clase de democracias virtuales donde los negocios y los lobbies dominan el caudal de la opinión pública

  12. Perspectivas de la niñez adulta: El cómic como espacio de denuncia desde la marginalidad de sus personajes

    Directory of Open Access Journals (Sweden)

    Ana Merino

    2010-01-01

    Full Text Available Este artículo analiza la representación de la niñez en varios cómics iberoamericanos: Mafalda de Quino, Paracuellos de Carlos Jiménez y Socorro de Miguel Rep. En ellos se articula la infancia desde una perspectiva adulta y crítica con la sociedad mostrando una dimensión comprometida que interpela al lector. This article analyzes the representation of childhood in several Latin American comics: Mafalda by Quino, Paracuellos by Carlos Jiménez, and Socorro by Miguel Rep. In these comics, infancy is articulated from an adult angle critical with society, showing a dimension of commitment appealing to their readership.

  13. Umbilical Cable Recovery Load Analysis

    Institute of Scientific and Technical Information of China (English)

    YAN Shu-wang; JIA Zhao-lin; FENG Xiao-wei; LI Shi-tao

    2013-01-01

    Umbilical cable is a kind of integrated subsea cable widely used in the exploration and exploitation of oil and gas field.The severe ocean environment makes great challenges to umbilical maintenance and repair work.Damaged umbilical is usually recovered for the regular operation of the offshore production system.Analysis on cables in essence is a two-point boundary problem.The tension load at the mudline must be known first,and then the recovery load and recovery angle on the vessel can be solved by use of catenary equation.The recovery analysis also involves umbilicalsoil interaction and becomes more complicated.Calculation methods for recovery load of the exposed and buried umbilical are established and the relationship between the position of touch down point and the recovery load as well as the recovery angle and recovery load are analyzed.The analysis results provide a theoretical reference for offshore on-deck operation.

  14. Determination of the minimum inhibitory concentration (MIC and mutant prevention concentration (MPC of selected antimicrobials in bovine and swine Pasteurella multocida, Escherichia coli, and Staphylococcus aureus isolates

    Directory of Open Access Journals (Sweden)

    Kateřina Nedbalcová

    2015-01-01

    Full Text Available We compared the values of the minimum inhibitory concentration (MIC and mutant prevention concentration (MPC values ​​of three antimicrobial agents for 72 bovine isolates of Pasteurella multocida, 80 swine isolates of P. multocida, 80 bovine isolates of Escherichia coli, 80 swine isolates of E. coli, and 80 isolates of Staphylococcus aureus from bovine mastitis. The ratio of MIC90​​/MPC90 which limited mutant selection window (MSW was ≤ 0.12/4 mg/l for enrofloxacin, 0.5/≥ 64 mg/l for florfenicol and 4/≥ 128 mg/l for tulathromycin in bovine P. multocida isolates, ≤ 0.12/2 mg/l for enrofloxacin, 0.5/≥ 64 mg/l for florfenicol and 4/≥ 128 mg/l for tulathromycin in swine P. multocida isolates, 1/16 mg/l for enrofloxacin, 8/≥ 64 mg/l for florfenicol and 8/≥ 128 mg/l for tulathromycin in bovine E. coli isolates, 0.5/16 mg/l for enrofloxacin, ≥ 64/≥ 64 mg/l for florfenicol and 8/≥ 128 mg/l for tulathromycin in swine E. coli isolates, and 0.25/16 mg/l for enrofloxacin, 4/≥ 64 mg/l for florfenicol and 4/≥ 128 mg/l for tulathromycin in S. aureus isolates. These findings indicate that the dosage of antimicrobial agents to achieve serum concentration equal to or higher than MPC could reduce selection of resistant bacterial subpopulation.

  15. Dreams of a New Medium

    Directory of Open Access Journals (Sweden)

    Aden Evens

    2009-01-01

    Full Text Available Problematic at best, the desire for a transparent interface nevertheless drives much of digital culture and technology. But not the Web; or at least, not Web 1.0. Thoroughly commercialized, comfortably parsed into genres, serving billions of pages of predigested content to passive consumers, the World Wide Web as developed in the '90s unabashedly embraces its role as medium. While so many digital technologies work to hide their mediacy--drawing in the user with a total simulated sensorium, dematerializing the resistances of size and weight, untangling the knots of cables tying user to machine and machine to cubicle, minimizing the interface--Web 1.0 proudly clings to the browser as a glaring reminder of its medial character. While Web 2.0 has not forsaken the browser altogether, it nevertheless seems to offer a different sort of mediation. Arising alongside the atomization of browser functions, the ubiquitization of connectivity, and the coincidence of producer and user, Web 2.0 retains the form of a medium while reaching for the experiential logic of immediacy. This is not the immediacy of the transparent interface; rather, Web 2.0 effects an immediate relationship between the individual and culture. The interface does not disappear, but its mediacy is subsumed under the general form of cultural participation. Focusing on the "version upgrade" from Web 1.0 to 2.0, this essay will explore the implications for mediacy of this transition, noting that the fantasy of immediacy which drives Web 2.0 is layered and complex. The typical account of immediacy proposes to eliminate the interface and so construct a virtual reality (VR. But Web 2.0 mostly sidesteps the virtual, propelled instead by a fantasy of intuition in which the Web already knows what you want because it is you. Crucially, fantasies about the digital are effective: the computer's futurity inhabits our world, finding its expression in politics, advertising, budgeting, strategic planning

  16. Research of fluidized medium treatment

    International Nuclear Information System (INIS)

    Chishiro, Ryo; Higashi, Tatsuhiro; Yamazaki, Seiichiro

    2002-03-01

    The activity coefficient of uranium fluoride in fluoride was determined by a cyclic voltammetry and equilibrium potential measurement. The kind of uranium compound in NaF-AlF 3 -Al 2 O 3 -F 4 system was determined by the cyclic voltammetry. With reducing from U(3) to U(0) by the reduction reaction during uranium precipitation, the activity coefficient of UF 3 in cryolite fused salt with uranium metal and uranium fluoride was measured by the electron motive force (EMF) method. The results showed that the redox potential of uranium is almost same value of aluminum, so that, both uranium and aluminum are collected by electrolytic recovery, because the concentration of aluminum is higher than uranium in the fused salt. It is necessary to add the after-treatment such as distillation. Alumina was soluble in fluoride molten salt and oxidized uranium fluoride to uranium oxide. The results showed separation and collection of uranium is possible, because uranium oxide was not soluble and precipitated in fluoride molten salt. (S.Y.)

  17. Selection of culture medium and conditions for the production of ...

    African Journals Online (AJOL)

    defined medium–A, defined medium-B, synthetic medium, rich medium and industrial medium) showed that the synthetic medium yielded maximum yeast biomass (12.8 g/LDCW) followed by rich medium (11.7 g/L DCW) and defined medium B ...

  18. Pyrochemical recovery of actinides

    International Nuclear Information System (INIS)

    Laidler, J.J.

    1993-01-01

    This report discusses an important advantage of the Integral Fast Reactor (IFR) which is its ability to recycle fuel in the process of power generation, extending fuel resources by a considerable amount and assuring the continued viability of nuclear power stations by reducing dependence on external fuel supplies. Pyroprocessing is the means whereby the recycle process is accomplished. It can also be applied to the recovery of fuel constituents from spent fuel generated in the process of operation of conventional light water reactor power plants, offering the means to recover the valuable fuel resources remaining in that material

  19. Pyrochemical recovery of actinides

    Energy Technology Data Exchange (ETDEWEB)

    Laidler, J.J.

    1993-03-01

    This report discusses an important advantage of the Integral Fast Reactor (IFR) which is its ability to recycle fuel in the process of power generation, extending fuel resources by a considerable amount and assuring the continued viability of nuclear power stations by reducing dependence on external fuel supplies. Pyroprocessing is the means whereby the recycle process is accomplished. It can also be applied to the recovery of fuel constituents from spent fuel generated in the process of operation of conventional light water reactor power plants, offering the means to recover the valuable fuel resources remaining in that material.

  20. Pyrochemical recovery of actinides

    Energy Technology Data Exchange (ETDEWEB)

    Laidler, J.J.

    1993-01-01

    This report discusses an important advantage of the Integral Fast Reactor (IFR) which is its ability to recycle fuel in the process of power generation, extending fuel resources by a considerable amount and assuring the continued viability of nuclear power stations by reducing dependence on external fuel supplies. Pyroprocessing is the means whereby the recycle process is accomplished. It can also be applied to the recovery of fuel constituents from spent fuel generated in the process of operation of conventional light water reactor power plants, offering the means to recover the valuable fuel resources remaining in that material.

  1. Recovery of hydrocarbon oils

    Energy Technology Data Exchange (ETDEWEB)

    1941-02-10

    A process is disclosed for recovery of hydrocarbon oils, especially lubricating oils or diesel oils, through pressure hydrogenation of distillation, extraction of hydrogenation products from coal or coaly materials or from oils such as mineral oils or tars in liquid phase by use in a reaction vessel of fixed-bed catalysts, characterized in that as starting material is employed material which has been freed of asphaltic and resinous material by hydrogenation refining, vacuum-steam distillation, treatment with hydrogen-rich hydrocarbons (hydroforming), or sulfuric acid.

  2. Waste heat recovery system

    International Nuclear Information System (INIS)

    Phi Wah Tooi

    2010-01-01

    Full text: The Konzen in-house designed anaerobic digester system for the POME (Palm Oil Mill Effluent) treatment process is one of the registered Clean Development Mechanism (CDM) projects in Malaysia. It is an organic wastewater treatment process which achieves excellent co-benefits objectives through the prevention of water pollution and reduction of greenhouse gas emissions, which is estimated to be 40,000 to 50,000 t-CO 2 per year. The anaerobic digester was designed in mesophile mode with temperature ranging from 37 degree Celsius to 45 degree Celsius. A microorganisms growth is optimum under moderately warm temperature conditions. The operating temperature of the anaerobic digester needs to be maintained constantly. There are two waste heat recovery systems designed to make the treatment process self-sustaining. The heat recovered will be utilised as a clean energy source to heat up the anaerobic digester indirectly. The first design for the waste heat recovery system utilises heat generated from the flue gas of the biogas flaring system. A stainless steel water tank with an internal water layer is installed at the top level of the flare stack. The circulating water is heated by the methane enriched biogas combustion process. The second design utilizes heat generated during the compression process for the biogas compressor operation. The compressed biogas needs to be cooled before being recycled back into the digester tank for mixing purposes. Both the waste heat recovery systems use a design which applies a common water circulation loop and hot water tank to effectively become a closed loop. The hot water tank will perform both storage and temperature buffer functions. The hot water is then used to heat up recycled sludge from 30 degree Celsius to 45 degree Celsius with the maximum temperature setting at 50 degree Celsius. The recycled sludge line temperature will be measured and monitored by a temperature sensor and transmitter, which will activate the

  3. The interstellar medium in galaxies

    CERN Document Server

    1997-01-01

    It has been more than five decades ago that Henk van de Hulst predicted the observability of the 21-cm line of neutral hydrogen (HI ). Since then use of the 21-cm line has greatly improved our knowledge in many fields and has been used for galactic structure studies, studies of the interstellar medium (ISM) in the Milky Way and other galaxies, studies of the mass distribution of the Milky Way and other galaxies, studies of spiral struc­ ture, studies of high velocity gas in the Milky Way and other galaxies, for measuring distances using the Tully-Fisher relation etc. Regarding studies of the ISM, there have been a number of instrumen­ tal developments over the past decade: large CCD's became available on optical telescopes, radio synthesis offered sensitive imaging capabilities, not only in the classical 21-cm HI line but also in the mm-transitions of CO and other molecules, and X-ray imaging capabilities became available to measure the hot component of the ISM. These developments meant that Milky Way was n...

  4. Studies in medium energy physics

    International Nuclear Information System (INIS)

    Green, A.; Hoffmann, G.W.; McDonough, J.; Purcell, M.J.; Ray, R.L.; Read, D.E.; Worn, S.D.

    1991-12-01

    This document constitutes the (1991--1992) technical progress report and continuation proposal for the ongoing medium energy nuclear physics research program supported by the US Department of Energy through special Research Grant DE-FG05-88ER40444. The experiments discussed are conducted at the Los Alamos National Laboratory's (LANL) Clinton P. Anderson Meson Physics Facility (LAMPF) and the Alternating Gradient Synchrotron (AGS) facility of the Brookhaven National Laboratory (BNL). The overall motivation for the work discussed in this document is driven by three main objectives: (1) provide hadron-nucleon and hadron-nucleus scattering data which serve to facilitate the study of effective two-body interactions, test (and possibly determine) nuclear structure, and help study reaction mechanisms and dynamics; (2) provide unique, first-of-a-kind ''exploratory'' hadron-nucleus scattering data in the hope that such data will lead to discovery of new phenomena and new physics; and (3) perform precision tests of fundamental interactions, such as rare decay searches, whose observation would imply fundamental new physics

  5. Butylcellosolve recovery activities results

    International Nuclear Information System (INIS)

    Caponetti, R.; Petrazzuolo, F.

    1988-01-01

    At Casaccia's Energy Research Center (C.R.E.) of the Italien Commission for Nuclear and Alternatives Energy Sources (ENEA) a components cleaning program is under way whose first phase is based on the use of an organic solvent named Butylcellosolve (2-butoxy-ethanol or Ethylene-Glicol-Monobutylether). The main reasons for which this solvent was preferred over others are: - the suitable values of its reaction rate with sodium; - its vapor pressure, equivalent at 20 and 50 0 C to 0.6 and 3.9 torr, respectively. This make it possible, in a comprehensive cleaning process, to carry out vacuum processing without the formation of large quantities of vapor. Butylcellosolve reects with metallic sodium as follows: R-OH + Na → R-ONa + 1/2H 2 . Consequently the organic recirculation becames sodium enriched and the concentration of alcoholic function decreases. Sodium concentration in solution can increase up to 10 + 20 g/it conveniently when we use the butylcellosolve as cleaning medium. On the other hand, when the butylcellosolve is used as rinsing medium, we estimate the most suitable sodium concentration equivalent to ∼ 10 -2 g/lt. The use of butylcellosolve as cleaning medium for activated-contaminated components brings, of course, to the formation of very large amount of liquid wastes having problematic disposal. It should be noted that disposal of these wastes is a very serious problem also in the case of non radioactive liquid. For this reason the definition of suitable methods to restore the butylcellosolve alcoholic function was recently valued very important and the activity reported in this paper was performed

  6. Empirical links between natural mortality and recovery in marine fishes.

    Science.gov (United States)

    Hutchings, Jeffrey A; Kuparinen, Anna

    2017-06-14

    Probability of species recovery is thought to be correlated with specific aspects of organismal life history, such as age at maturity and longevity, and how these affect rates of natural mortality ( M ) and maximum per capita population growth ( r max ). Despite strong theoretical underpinnings, these correlates have been based on predicted rather than realized population trajectories following threat mitigation. Here, we examine the level of empirical support for postulated links between a suite of life-history traits (related to maturity, age, size and growth) and recovery in marine fishes. Following threat mitigation (medium time since cessation of overfishing = 20 years), 71% of 55 temperate populations had fully recovered, the remainder exhibiting, on average, negligible change (impaired recovery). Singly, life-history traits did not influence recovery status. In combination, however, those that jointly reflect length-based mortality at maturity, M α , revealed that recovered populations have higher M α , which we hypothesize to reflect local adaptations associated with greater r max But, within populations, the smaller sizes at maturity generated by overfishing are predicted to increase M α , slowing recovery and increasing its uncertainty. We conclude that recovery potential is greater for populations adapted to high M but that temporal increases in M concomitant with smaller size at maturity will have the opposite effect. The recovery metric documented here ( M α ) has a sound theoretical basis, is significantly correlated with direct estimates of M that directly reflect r max , is not reliant on data-intensive time series, can be readily estimated, and offers an empirically defensible correlate of recovery, given its clear links to the positive and impaired responses to threat mitigation that have been observed in fish populations over the past three decades. © 2017 The Author(s).

  7. Recovery in SoccerPart II—Recovery Strategies

    OpenAIRE

    Nedelec, Mathieu; McCall, Alan; Carling, Chris; Legall, Franck; Berthoin, Serge; Dupont, Grégory

    2013-01-01

    International audience; In the formerly published part I of this two-part review, we examined fatigue after soccer matchplay and recovery kinetics of physical performance, and cognitive, subjective and biological markers. To reduce the magnitude of fatigue and to accelerate the time to fully recover after completion, several recovery strategies are now used in professional soccer teams. During congested fixture schedules, recovery strategies are highly required to alleviate post-match fatigue...

  8. Treatment of Source-Separated Blackwater: A Decentralized Strategy for Nutrient Recovery towards a Circular Economy

    OpenAIRE

    Melesse Eshetu Moges; Daniel Todt; Arve Heistad

    2018-01-01

    Using a filter medium for organic matter removal and nutrient recovery from blackwater treatment is a novel concept and has not been investigated sufficiently to date. This paper demonstrates a combined blackwater treatment and nutrient-recovery strategy and establishes mechanisms for a more dependable source of plant nutrients aiming at a circular economy. Source-separated blackwater from a student dormitory was used as feedstock for a sludge blanket anaerobic-baffled reactor. The effluent f...

  9. Optical illusions induced by rotating medium

    Science.gov (United States)

    Zang, XiaoFei; Huang, PengCheng; Zhu, YiMing

    2018-03-01

    Different from the traditional single-function electromagnetic wave rotators (rotate the electromagnetic wavefronts), we propose that rotating medium can be extended to optical illusions such as breaking the diffraction limit and overlapping illusion. Furthermore, the homogeneous but anisotropic rotating medium is simplified by homogeneous and isotropic positive-index materials according to the effective medium theory, which is helpful for future device fabrication. Finite element simulations for the two-dimensional case are performed to demonstrate these properties.

  10. Effect of ultrasonic intensity and frequency on oil/heavy-oil recovery from different wettability rocks

    Energy Technology Data Exchange (ETDEWEB)

    Naderi, K.; Babadagli, T. [Society of Petroleum Engineers, Canadian Section, Calgary, AB (Canada)]|[Alberta Univ., Edmonton, AB (Canada)

    2008-10-15

    This study identified the mechanisms that are responsible for additional oil recovery that is often observed following an earthquake. It focused on the theory that harmonics of low frequency waves create high frequency waves as they penetrate into rock formations. A series of experiments were conducted on oil-wet rocks with high oil viscosities. The objective was to better understand how ultrasonic energy affects oil recovery at core and pore scale. Cylindrical sandstone cores were placed in imbibition cells to examine how the presence of initial water saturation can affect recovery, and how the recovery changes for different oil viscosities. An increase in oil recovery was observed with ultrasonic energy in all cases. The additional recovery with ultrasonic energy lessened as the oil viscosity increased. Ultrasonic intensity and frequency were shown to be critical to the performance, which is important since ultrasonic waves have limited penetration into porous medium. This is a key disadvantage for commercializing this promising process for well stimulation. Therefore, the authors designed a set-up to measure the ultrasonic energy penetration capacity in different media, notably air, water and slurry. The set-up could identify which types of reservoirs are most suitable for ultrasonic application. Imbibition experiments revealed that ultrasonic radiation increases recovery, and is much more significant in oil wet cases, where initial water saturation facilitate oil recovery. Higher frequency showed a higher rate of recovery compared to lower frequency, but the ultimate recovery was not changed substantially. 46 refs., 1 tab., 16 figs.

  11. Recovery from a psychiatrist's viewpoint.

    Science.gov (United States)

    Diamond, Ronald J

    2006-09-01

    Recovery is not the same as cure. Recovery from mental illness is the process of having more to life than just illness. It is an ongoing process rather than simply a goal that can be achieved. Recovery from the stigma of mental illness may be as difficult as recovery from the illness itself. Several common, but incorrect, beliefs can interfere with the recovery process. Myths include the belief that the illness has an inherently downhill course, that rehabilitation is useful only after stabilization, and that people with schizophrenia can only work at low-level jobs. People who have schizophrenia have reported that their own process of recovery was helped by their determination to get better, an understanding of the illness, taking personal responsibility, having friends who accept them, an optimistic attitude, and spiritual beliefs that help them find meaning in life.

  12. Teaching recovery to medical students.

    LENUS (Irish Health Repository)

    Feeney, Larkin

    2013-03-01

    Community mental health services are evolving toward more holistic, patient-centered, recovery-based practices. This change necessitates an attitudinal shift from mental health workers, and training in recovery principles is helpful in achieving this change. Medical students often have narrow, doctor-centered concepts of mental health care. Traditional clinical placements in psychiatry do little to address this. We evaluated a recovery-focused teaching program for medical students in psychiatry.

  13. Global recovery process of thorium and rare earths in a nitrate medium

    International Nuclear Information System (INIS)

    Cailly, F.; Mottot, Y.

    1993-01-01

    The aqueous solution of thorium and rare earth nitrates, obtained by leaching the ore with nitric acid, is extracted by an organic phosphorous compound (phosphate, phosphonate, phosphinate or phosphine oxide) and a cationic extractant chosen among phosphoric acid di-esters. Extraction of thorium and rare earths is possible even in presence of phosphate ions in the aqueous solution. Thorium and rare earths are separated by liquid-liquid extraction of the organic phase

  14. Probabilistic accident sequence recovery analysis

    International Nuclear Information System (INIS)

    Stutzke, Martin A.; Cooper, Susan E.

    2004-01-01

    Recovery analysis is a method that considers alternative strategies for preventing accidents in nuclear power plants during probabilistic risk assessment (PRA). Consideration of possible recovery actions in PRAs has been controversial, and there seems to be a widely held belief among PRA practitioners, utility staff, plant operators, and regulators that the results of recovery analysis should be skeptically viewed. This paper provides a framework for discussing recovery strategies, thus lending credibility to the process and enhancing regulatory acceptance of PRA results and conclusions. (author)

  15. Business recovery: an assessment framework.

    Science.gov (United States)

    Stevenson, Joanne R; Brown, Charlotte; Seville, Erica; Vargo, John

    2018-07-01

    This paper presents a Business Recovery Assessment Framework (BRAF) to help researchers and practitioners design robust, repeatable, and comparable studies of business recovery in various post-disruption contexts. Studies assessing business recovery without adequately considering the research aims, recovery definitions, and indicators can produce misleading findings. The BRAF is composed of a series of steps that guide the decisions that researchers need to make to ensure: (i) that recovery is indeed being measured; (ii) that the indicators of recovery that are selected align with the objectives of the study and the definition of recovery; and, where necessary, (iii) that appropriate comparative control variables are in place. The paper draws on a large dataset of business surveys collected following the earthquakes in Canterbury, New Zealand, on 4 September 2010 and 22 February 2011 to demonstrate the varied conclusions that different recovery indicators can produce and to justify the need for a systematic approach to business recovery assessments. © 2018 The Author(s). Disasters © Overseas Development Institute, 2018.

  16. Speech recovery device

    Energy Technology Data Exchange (ETDEWEB)

    Frankle, Christen M.

    2004-04-20

    There is provided an apparatus and method for assisting speech recovery in people with inability to speak due to aphasia, apraxia or another condition with similar effect. A hollow, rigid, thin-walled tube with semi-circular or semi-elliptical cut out shapes at each open end is positioned such that one end mates with the throat/voice box area of the neck of the assistor and the other end mates with the throat/voice box area of the assisted. The speaking person (assistor) makes sounds that produce standing wave vibrations at the same frequency in the vocal cords of the assisted person. Driving the assisted person's vocal cords with the assisted person being able to hear the correct tone enables the assisted person to speak by simply amplifying the vibration of membranes in their throat.

  17. Speech recovery device

    Energy Technology Data Exchange (ETDEWEB)

    Frankle, Christen M.

    2000-10-19

    There is provided an apparatus and method for assisting speech recovery in people with inability to speak due to aphasia, apraxia or another condition with similar effect. A hollow, rigid, thin-walled tube with semi-circular or semi-elliptical cut out shapes at each open end is positioned such that one end mates with the throat/voice box area of the neck of the assistor and the other end mates with the throat/voice box area of the assisted. The speaking person (assistor) makes sounds that produce standing wave vibrations at the same frequency in the vocal cords of the assisted person. Driving the assisted person's vocal cords with the assisted person being able to hear the correct tone enables the assisted person to speak by simply amplifying the vibration of membranes in their throat.

  18. Radiation injuries and recovery

    International Nuclear Information System (INIS)

    Pauly, H.

    1974-01-01

    In memory of Prof. Dr. Langendorff, a survey and a cross-section are given of the development of radiobiology during the last 40 years. The importance of radiobiology is shown using several examples. The mechanisms and effects of radiation on man, animals and plants are discussed. Effects of radiation and radiolesious are explained down ot the molecular field, and their importance is discussed quantitatively with stochastic considerations. Stress is laid upon recovering from radiolesious. It is tried to explain recovery quantitatively in all its several sorts. Using all these deliberations, the author also tries to give a wide spectrum for radiation protection. These fundamental deliberations and works of Prof. Dr. Langendorff are guidelines of great importance also for radiation protection in connection with the protection of the civil population. (GSE) [de

  19. Desulfurisation and sulfur recovery

    Energy Technology Data Exchange (ETDEWEB)

    Hughes, P.; Finn, A.; Scott, L. [Costain Oil, Gas and Process Ltd (United Kingdom)

    2001-09-01

    This article highlights technical issues associated with different sulphur recovery processes in the hydrocarbon processing industry. Details are given of the Stretford process developed by British Gas for the removal of low concentrations of hydrogen sulphide from natural gas and other hydrocarbon gases; the SulFerox process developed by Shell and Dow for removing moderate amounts of sulphur from contaminated gases using a proprietary iron salt for extracting the sulphur; solvent systems for removing moderately high concentrations of hydrogen sulphide in sour gas or liquid petroleum gases (LPG); the simple Claus process involving the partial combustion of hydrogen sulphide forming sulphur dioxide which reacts with hydrogen sulphide to form sulphur; and enhanced Claus processes. Sour water stripping processes for hydrogen sulphide contaminated water from hydrocarbon processing, tail gas treatment of Claus plant offgases, and hydrotreating are also discussed.

  20. Gas recovery process

    International Nuclear Information System (INIS)

    Schmidt, W.B.; Lewis, W.W.; Edmiston, A.; Klauser, G.

    1980-01-01

    In order to decontaminate a gas stream containing radioactive krypton, a preliminary step of removing oxygen and oxides of nitrogen by catalytic reaction with hydrogen is performed. The gas stream is then passed serially through a drier, a carbon dioxide adsorber and a xenon adsorber to remove sequentially water, CO 2 and xenon therefrom. The gas exiting the xenon adsorber is passed to a krypton recovery plant wherein krypton is concentrated to a first level in a primary distillation column by contact with a reflux liquid in a packed section of the column. The liquid and vapour collecting at the bottom of the column is passed to a separator in which the liquid is separated from the vapour. The liquid is partially evaporated in a vessel to increase concentration thereof and is brought to a concentration of approximately 90 mole % or greater in a second distillation column thereby enabling efficient storage of a radioactive krypton product. (author)

  1. Enhanced oil recovery system

    Science.gov (United States)

    Goldsberry, Fred L.

    1989-01-01

    All energy resources available from a geopressured geothermal reservoir are used for the production of pipeline quality gas using a high pressure separator/heat exchanger and a membrane separator, and recovering waste gas from both the membrane separator and a low pressure separator in tandem with the high pressure separator for use in enhanced oil recovery, or in powering a gas engine and turbine set. Liquid hydrocarbons are skimmed off the top of geothermal brine in the low pressure separator. High pressure brine from the geothermal well is used to drive a turbine/generator set before recovering waste gas in the first separator. Another turbine/generator set is provided in a supercritical binary power plant that uses propane as a working fluid in a closed cycle, and uses exhaust heat from the combustion engine and geothermal energy of the brine in the separator/heat exchanger to heat the propane.

  2. Waste heat recovery system

    Energy Technology Data Exchange (ETDEWEB)

    Ernst, Timothy C.; Zigan, James A.

    2017-12-19

    A waste heat recovery system includes a Rankine cycle (RC) circuit having a pump, a boiler, an energy converter, and a condenser fluidly coupled via conduits in that order, to provide additional work. The additional work is fed to an input of a gearbox assembly including a capacity for oil by mechanically coupling to the energy converter to a gear assembly. An interface is positioned between the RC circuit and the gearbox assembly to partially restrict movement of oil present in the gear assembly into the RC circuit and partially restrict movement of working fluid present in the RC circuit into the gear assembly. An oil return line is fluidly connected to at least one of the conduits fluidly coupling the RC components to one another and is operable to return to the gear assembly oil that has moved across the interface from the gear assembly to the RC circuit.

  3. Los insectos como Estrategia Didactica en la enseñanza de la Ecologia, a través del Cómic

    Directory of Open Access Journals (Sweden)

    Jairo Robles Piñeros

    2013-07-01

    Full Text Available Este trabajo se desarrolló con el objetivo de implementar una estrategia didáctica basada en el estudio de los insectos como organismo tipo, haciendo énfasis en su importancia filogenética y ecológica. Por consiguiente, se abordaron algunos conceptos estructurantes de ecología pertinentes y necesarios en los grados octavos del Instituto Pedagógico Nacional (IPN; se propició un acercamiento a las problemáticas ambientales actuales y se promovió la conservación biológica desde el contexto inmediato. Parallevar a cabo estos objetivos, el proyecto se fundamentó en la realización de un cómic que funcionó como herramienta y recurso educativo que articula conceptos de entomología, ecología, conservación y permitió contribuir en la alfabetización científica del estudiante a través de un lenguaje sencillo y atractivo, hecho que además brindó la posibilidad de abordar la ciencia desde una visión holística y contextual. La finalización del proyecto de investigación permitió la evaluación de la estrategia y la materialización del cómic. El seguimiento realizado posibilitó visualizar la ampliación delas concepciones en uno de los obstáculos en el aprendizaje de las ciencias referido a los conocimientos previos, lo cual desarrolló en los estudiantes actitudes y tendencias positivas frente a los insectos y la naturaleza, su conservación y la responsabilidad inminente con el medio ambiente. El lenguaje cotidiano, promovido por el contexto social y cultural, se concibe como el principal obstáculo epistemológico en la enseñanza de la ecología. El abordaje de conceptos básicos en ecología fue un factor de transformación en las actitudes y percepciones de los estudiantes con respecto a los insectos. En cuanto al cómic, este se mantiene como una herramienta llamativa, eficaz y motivadora para la enseñanza de las temáticas científicas y promueve al estudiante actuar frente a las problemáticas ambientales más pr

  4. Possibilities of heat energy recovery from greywater systems

    Science.gov (United States)

    Niewitecka, Kaja

    2018-02-01

    Waste water contains a large amount of heat energy which is irretrievably lost, so it is worth thinking about the possibilities of its recovery. It is estimated that in a residential building with full sanitary fittings, about 70% of the total tap water supplied is discharged as greywater and could be reused. The subject of the work is the opportunity to reuse waste water as an alternative source of heat for buildings. For this purpose, the design of heat exchangers used in the process of greywater heat recovery in indoor sewage systems, public buildings as well as in industrial plants has been reviewed. The possibility of recovering heat from waste water transported in outdoor sewage systems was also taken into consideration. An exemplary waste water heat recovery system was proposed, and the amount of heat that could be obtained using a greywater heat recovery system in a residential building was presented. The work shows that greywater heat recovery systems allow for significant savings in preheating hot tap water, and the rate of cost reimbursement depends on the purpose of the building and the type of installation. At the same time, the work shows that one should adjust the construction solutions of heat exchangers and indoor installations in buildings to the quality of the medium flowing, which is greywater.

  5. Recovery of lanthanides

    International Nuclear Information System (INIS)

    Tilley, G.L.; Doyle, W.E.

    1990-01-01

    This paper discusses a method for recovering a lanthanide and thorium from a material containing a fluorine compound and the lanthanide and thorium. It comprises a. obtaining the material from a roasted, acid-leached bastnasite ore; b. forming a mixture of the material with at least about ten weight percent of silica; c. contacting the mixture with sulfuric acid; d. heating the mixture and sulfuric acid to a temperature of at least about 150 degrees C for at least about 3 hours to cause most of the fluorine to be released as a volatile material containing silicon and fluorine; e. contacting the reacted mixture with an aqueous medium consisting essentially of water to solubilize the lanthanide and thorium while leaving an insoluble residue; and f. separating the aqueous solution of the lanthanide and thorium from the insoluble residue

  6. Recovery in soccer : part ii-recovery strategies.

    Science.gov (United States)

    Nédélec, Mathieu; McCall, Alan; Carling, Chris; Legall, Franck; Berthoin, Serge; Dupont, Gregory

    2013-01-01

    In the formerly published part I of this two-part review, we examined fatigue after soccer matchplay and recovery kinetics of physical performance, and cognitive, subjective and biological markers. To reduce the magnitude of fatigue and to accelerate the time to fully recover after completion, several recovery strategies are now used in professional soccer teams. During congested fixture schedules, recovery strategies are highly required to alleviate post-match fatigue, and then to regain performance faster and reduce the risk of injury. Fatigue following competition is multifactorial and mainly related to dehydration, glycogen depletion, muscle damage and mental fatigue. Recovery strategies should consequently be targeted against the major causes of fatigue. Strategies reviewed in part II of this article were nutritional intake, cold water immersion, sleeping, active recovery, stretching, compression garments, massage and electrical stimulation. Some strategies such as hydration, diet and sleep are effective in their ability to counteract the fatigue mechanisms. Providing milk drinks to players at the end of competition and a meal containing high-glycaemic index carbohydrate and protein within the hour following the match are effective in replenishing substrate stores and optimizing muscle-damage repair. Sleep is an essential part of recovery management. Sleep disturbance after a match is common and can negatively impact on the recovery process. Cold water immersion is effective during acute periods of match congestion in order to regain performance levels faster and repress the acute inflammatory process. Scientific evidence for other strategies reviewed in their ability to accelerate the return to the initial level of performance is still lacking. These include active recovery, stretching, compression garments, massage and electrical stimulation. While this does not mean that these strategies do not aid the recovery process, the protocols implemented up until

  7. Recordable storage medium with protected data area

    NARCIS (Netherlands)

    2005-01-01

    The invention relates to a method of storing data on a rewritable data storage medium, to a corresponding storage medium, to a corresponding recording apparatus and to a corresponding playback apparatus. Copy-protective measures require that on rewritable storage media some data must be stored which

  8. Electromagnetic Sources in a Moving Conducting Medium

    DEFF Research Database (Denmark)

    Johannsen, Günther

    1971-01-01

    The problem of an arbitrary source distribution in a uniformly moving, homogeneous, isotropic, nondispersive, conducting medium is solved. The technique used is to solve the problem in the rest system of the medium and then write the result in an appropriate four-dimensional, covariant form which...

  9. Kultivasi Scenedesmus SP. Pada Medium Air Limbah

    OpenAIRE

    Kawaroe, Mujizat

    2011-01-01

    Proses fotosintesis pada mikroalga membutuhkan CO2 dan cahaya matahari serta nutrien untuk pertumbuhannya. Kultivasi Scenedesmus sp. pada medium air limbah bertujuan guna mencukupi kebutuhan mikroalga akan nutrien dan mengurangi masukan dari bahan kimia yang terkandung dalam air limbah tersebut ke lingkungan. Kultivasi Scenedesmus sp. dilakukan selama tujuh hari pada medium air limbah industri tanpa penambahan nutri...

  10. Effective medium theory for anisotropic metamaterials

    KAUST Repository

    Zhang, Xiujuan; Wu, Ying

    2015-01-01

    -dimensional metamaterial composed of a rectangular array of elliptic cylinders and derive an effective medium theory for such a metamaterial. We find that it is possible to obtain a closed-form analytical solution for the anisotropic effective medium parameters, provided

  11. Selective medium for aerobic incubation of Campylobacter

    Science.gov (United States)

    Studies were conducted on the formulation of a selective medium that could be used to isolate Campylobacter from mixed bacterial cultures using aerobic incubation. A non-selective, basal broth medium was prepared and supplemented with Bolton, Cefex, or Skirrow antibiotic mixtures. The ability of pur...

  12. Effective medium theory for anisotropic metamaterials

    KAUST Repository

    Zhang, Xiujuan

    2015-01-20

    Materials with anisotropic material parameters can be utilized to fabricate many fascinating devices, such as hyperlenses, metasolids, and one-way waveguides. In this study, we analyze the effects of geometric anisotropy on a two-dimensional metamaterial composed of a rectangular array of elliptic cylinders and derive an effective medium theory for such a metamaterial. We find that it is possible to obtain a closed-form analytical solution for the anisotropic effective medium parameters, provided the aspect ratio of the lattice and the eccentricity of the elliptic cylinder satisfy certain conditions. The derived effective medium theory not only recovers the well-known Maxwell-Garnett results in the quasi-static regime, but is also valid beyond the long-wavelength limit, where the wavelength in the host medium is comparable to the size of the lattice so that previous anisotropic effective medium theories fail. Such an advance greatly broadens the applicable realm of the effective medium theory and introduces many possibilities in the design of structures with desired anisotropic material characteristics. A real sample of a recently theoretically proposed anisotropic medium, with a near-zero index to control the flux, is achieved using the derived effective medium theory, and control of the electromagnetic waves in the sample is clearly demonstrated.

  13. Air quality and climate change, Topic 3 of the Model Inter-Comparison Study for Asia Phase III (MICS-Asia III) - Part 1: Overview and model evaluation

    Science.gov (United States)

    Gao, Meng; Han, Zhiwei; Liu, Zirui; Li, Meng; Xin, Jinyuan; Tao, Zhining; Li, Jiawei; Kang, Jeong-Eon; Huang, Kan; Dong, Xinyi; Zhuang, Bingliang; Li, Shu; Ge, Baozhu; Wu, Qizhong; Cheng, Yafang; Wang, Yuesi; Lee, Hyo-Jung; Kim, Cheol-Hee; Fu, Joshua S.; Wang, Tijian; Chin, Mian; Woo, Jung-Hun; Zhang, Qiang; Wang, Zifa; Carmichael, Gregory R.

    2018-04-01

    Topic 3 of the Model Inter-Comparison Study for Asia (MICS-Asia) Phase III examines how online coupled air quality models perform in simulating high aerosol pollution in the North China Plain region during wintertime haze events and evaluates the importance of aerosol radiative and microphysical feedbacks. A comprehensive overview of the MICS-Asia III Topic 3 study design, including descriptions of participating models and model inputs, the experimental designs, and results of model evaluation, are presented. Six modeling groups from China, Korea and the United States submitted results from seven applications of online coupled chemistry-meteorology models. Results are compared to meteorology and air quality measurements, including data from the Campaign on Atmospheric Aerosol Research Network of China (CARE-China) and the Acid Deposition Monitoring Network in East Asia (EANET). The correlation coefficients between the multi-model ensemble mean and the CARE-China observed near-surface air pollutants range from 0.51 to 0.94 (0.51 for ozone and 0.94 for PM2.5) for January 2010. However, large discrepancies exist between simulated aerosol chemical compositions from different models. The coefficient of variation (SD divided by the mean) can reach above 1.3 for sulfate in Beijing and above 1.6 for nitrate and organic aerosols in coastal regions, indicating that these compositions are less consistent from different models. During clean periods, simulated aerosol optical depths (AODs) from different models are similar, but peak values differ during severe haze events, which can be explained by the differences in simulated inorganic aerosol concentrations and the hygroscopic growth efficiency (affected by varied relative humidity). These differences in composition and AOD suggest that future models can be improved by including new heterogeneous or aqueous pathways for sulfate and nitrate formation under hazy conditions, a secondary organic aerosol (SOA) formation chemical

  14. Determination Of Prevalence Of Methicillin Resistant Staphylococcus Infections Through Measurement Of Mics Of S. Aureus Isolates Imam Hospital (November 2001 To January 2003

    Directory of Open Access Journals (Sweden)

    M. Mohraz

    2003-08-01

    Full Text Available Methicillin resistant staphylococcus aureus (MRSA is a predominantly nosocomial pathogen which its prevalence has increased worldwide over the past three decades."nMaterials and Methods: This is a descriptive cross-sectional study. The following study is designed for determination of prevalence of MRSA infection through measurement of MICs of S. aureus isolates in Imam Khomeini Hospital (a teaching hospital from November 2001 to January 2003. A total number of 402 specimens were isolated and specified as S. aureus by Imam Khomeini microbiology lab. Demographic and clinical data and results of MIC were analysed by Epilnfo 6 software."nResults: During the study, staphylococcus aureus was isolated from 402 patients that 187 (46.5% of isolates were MRSA and 215 (53.5% were MSSA. Of 402 patients, 254 (63.2% were male and 148 (36.8% were female. The difference of the prevalence of MRSA between males and females was not statistically significant (p= 0.09. The difference in mean age in MRSA and MSSA groups was not statistically significant (p= 0.55. In the age group of < 1 month, the prevalence of MRSA infection was significantly higher than other groups (P= 0.01."nConclusion: In this study, the prevalence of MRSA infection was increased, statistically significant in the presence of such factors as sepsis, longer duration of hospitalization, hospital- acquired infection, history of invasive procedure, history of antimicrobials used in the past 3 months and type of administered antimicrobial (s, history of hospitalization in the preceding year, certain underlying diseases, type of admission ward, type of infection, type of specimen and type of administered antimicrobials for treatment. Surprisingly, the prevalence of MRSA infection in IV drug user group was low that was statistically significant (p< 0.0001. In this study, there was no statistically significant difference in outcome between MRSA infected and MSSA infected patients. Based on results of

  15. El vídeo, el cómic y el rap: una forma diferente de desbloquear al candidato del DELE

    Directory of Open Access Journals (Sweden)

    Florencia Battagliero Bocco

    2017-11-01

    Full Text Available Resumen: El objetivo del presente artículo es trabajar y reforzar las destrezas y competencias necesarias para aprobar el Diploma de Español como Lengua Extranjera. Para ello, se planteará una serie de recursos que buscan desbloquear al estudiante en un ambiente distendido, sobre todo los días previos al examen. La propuesta se centrará en la Prueba de Expresión e Interacción Orales, concretamente en la tarea 3 del nivel B1 y en la tarea 2 del nivel B2, que corresponden a la descripción de una fotografía. Se empleará, por una parte, un vídeo de carácter estático (donde el interlocutor no expresa movimientos corporales pronunciados y por otra, cómics de Argentina que a su vez servirán para ampliar el léxico en la variante rioplatense. Por último, se tratará el uso del rap como herramienta para mejorar la pronunciación, entonación y el empleo del lenguaje no verbal. Palabras claves: DELE, vídeo, cómic, rap.   Abstract: The purpose of the following essay is to train and to strengthen the skills and the competences required to pass the “Spanish as a Foreign Language Certificate”. In order to do so, we will first consider various resources which aim to release students from any kind of stress by setting up a relaxed atmosphere – especially a few days before the exam. The focus of the present essay has to be linked to the Expression and Oral Interaction tests and above all to the assignments 3 (B1 level and 2 (B2 level, and their picture descriptions. On the one hand, we will use a static video and, on the other hand, we will tackle Argentinian comics in order to expand students’ knowledge of the Río de la Plata lexicon. Finally, we will deal with the use of rap as a tool to improve pronunciation, intonation, and non-verbal communication. Key words: DELE, video, comic, rap.

  16. Thermal recovery simulation at the pore-network level; Simulacao de recuperacao termica em escala microscopica

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira, Claudio L.N.; Almeida, Murilo P.; Andrade Junior, Jose S. [Universidade Federal do Ceara (UFC), Fortaleza, CE (Brazil); Herrmann, Hans J. [Eidgenossische Technische Hochschule Zurich (ETHZ), Zurich (Switzerland)

    2008-07-01

    We have investigated the effect of temperature in penetration of an inviscid fluid into a porous media saturated with a very high viscous fluid. Gradient of temperature is applied across the medium. The viscosity of the defending fluid is considered as an exponential-like function with temperature. This scheme represents a small fraction of a heavy oil reservoir where steam injection is applied. The results show that the recovery of the viscous fluid is a hyperbolic tangent function with the difference of temperature, where it has a maximum recovery for high gradient. Our results show, also, that the recovery efficiency can increase substantially with the gradient of temperature. (author)

  17. Gold biorecovery from e-waste: An improved strategy through spent medium leaching with pH modification.

    Science.gov (United States)

    Natarajan, Gayathri; Ting, Yen-Peng

    2015-10-01

    Rapid technological advancement and relatively short life time of electronic goods have resulted in an alarming growth rate of electronic waste which often contains significant quantities of toxic and precious metals. Compared to conventional recovery methods, bioleaching is an environmentally friendly process for metal extraction. Gold was bioleached from electronic scrap materials (ESM) via gold-cyanide complexation using cyanide produced from pure and mixed cultures of cyanogenic bacteria Chromobacterium violaceum, Pseudomonas aeruginosa and Pseudomonas fluorescens. As ESM was toxic to the bacteria, a two-step bioleaching approach was adopted where the solid waste was added to the bacterial culture after it has reached maximum growth and cyanide production during early stationary phase. Pure culture of C. violaceum showed the highest cyanide production, yielding maximum gold recovery of 11.3% at 0.5% w/v pulp density of ESM in two-step bioleaching. At the same pulp density of ESM, spent medium bioleaching using bacterial cell-free metabolites achieved gold recovery of 18%. Recovery increased to 30% when the pH of the spent medium was increased to shift the equilibrium in favor of cyanide ions production. It is demonstrated for the first time that pH modification of spent medium further improved metal solubilization and yielded higher metal recovery (compared to two-step bioleaching). Copyright © 2015 Elsevier Ltd. All rights reserved.

  18. Micropropagation of Alstroemeria in liquid medium using slow release of medium components

    NARCIS (Netherlands)

    Klerk, de G.J.M.; Brugge, ter J.

    2010-01-01

    Alstroemeria rhizomes were micropropagated on semi-solid medium (AM) and in liquid medium (LM). In LM, growth was much enhanced (ca. 70%). Adequate gas exchange was crucial. This was obtained by agitation and in static medium by a sufficient large contact area of the explant and the gaseous

  19. Recovery from Binge Eating Disorder

    Science.gov (United States)

    Krentz, Adrienne; Chew, Judy; Arthur, Nancy

    2005-01-01

    The purpose of this study was to characterize the psychological processes of recovery from binge eating disorder (BED). A model was developed by asking the research question, "What is the experience of recovery for women with BED?" Unstructured interviews were conducted with six women who met the DSM-IV criteria for BED, and who were recovered…

  20. SUPRA - Enhanced upset recovery simulation

    NARCIS (Netherlands)

    Groen, E.; Ledegang, W.; Field, J.; Smaili, H.; Roza, M.; Fucke, L.; Nooij, S.; Goman, M.; Mayrhofer, M.; Zaichik, L.E.; Grigoryev, M.; Biryukov, V.

    2012-01-01

    The SUPRA research project - Simulation of Upset Recovery in Aviation - has been funded by the European Union 7th Framework Program to enhance the flight simulation envelope for upset recovery simulation. Within the project an extended aerodynamic model, capturing the key aerodynamics during and

  1. Coupling of MIC-3 overexpression with the chromosome 11 and 14 root-knot nematode (RKN) (Meloidogyne incognita) resistance QTLs provides insights into the regulation of the RKN resistance response in Upland cotton...

    Science.gov (United States)

    High levels of resistance to root-knot nematode (RKN) (Meloidogyne incognita) in Upland cotton (Gossypium hirsutum) is mediated by two major quantitative trait loci (QTL) located on chromosomes 11 and 14. We had previously determined that MIC-3 expression played a direct role in suppressing RKN egg...

  2. El problema de las concepciones alternativas en la actualidad (parte III. utilización didáctica de los errores conceptuales que aparecen en cómics, prensa, novelas y libros de texto

    Directory of Open Access Journals (Sweden)

    Carrascosa, J.

    2006-01-01

    Full Text Available La existencia de graves errores conceptuales en artículos de prensa, novelas, cómics e incluso libros de texto está relacionada con el origen y persistencia de determinadas ideas alternativas. Cabe plantearse si no podrían utilizarse estos mismos medios para contribuir al tratamiento y el cambio de tales ideas.

  3. El problema de las concepciones alternativas en la actualidad (parte III). Utilización didáctica de los errores conceptuales que aparecen en cómics, prensa, novelas y libros de texto

    OpenAIRE

    Jaime Carrascosa-Alís

    2006-01-01

    La existencia de graves errores conceptuales en artículos de prensa, novelas, cómics e incluso libros de texto está relacionada con el origen y persistencia de determinadas ideas alternativas. Cabe plantearse si no podrían utilizarse estos mismos medios para contribuir al tratamiento y el cambio de tales ideas.

  4. Brief Report: The Identity Style Inventory (ISI-3) and the Utrecht-Management of Identity Commitments Scale (U-MICS)--Factor Structure, Reliability, and Convergent Validity in French-Speaking University Students

    Science.gov (United States)

    Zimmermann, Gregoire; Mahaim, Elodie Biermann; Mantzouranis, Gregory; Genoud, Philippe A.; Crocetti, Elisabetta

    2012-01-01

    The purpose of this study was to evaluate the factor structure and the reliability of the French versions of the Identity Style Inventory (ISI-3) and the Utrecht-Management of Identity Commitments Scale (U-MICS) in a sample of college students (N = 457, 18-25 years old). Confirmatory factor analyses confirmed the hypothesized three-factor solution…

  5. Process and installation for heat recovery. Verfahren und Anlage zur Waermerueckgewinnung

    Energy Technology Data Exchange (ETDEWEB)

    Zeller, M.

    1990-01-10

    The patent describes a method for heat recovery from the warmer of two separately conducted streams of a fluid, whereby heat is recovered through a first heat exchanger in the warmer stream of medium, a heat transfer medium in a transmitting circuit and a second heat exchanger in the cooler stream of fluid, whereby the transmitting circuit includes both heat exchangers, characterized in that the recovered thermic output ({Delta}t.Q) is continuously detected and a regulation of the quantity (Q) of heat transfer medium in this circuit to maximum thermic output is effected. (author) 4 figs., 2 refs.

  6. Indium recovery by solvent extraction

    International Nuclear Information System (INIS)

    Fortes, Marilia Camargos Botelho

    1999-04-01

    Indium has been recovered as a byproduct from residues generated from the sulfuric acid leaching circuits in mineral plants for zinc recovery. Once its recovery comes from the slags of other metals recovery, it is necessary to separate it from the other elements which usually are present in high concentrations. Many works have been approaching this separation and indicate the solvent extraction process as the main technique used. In Brazilian case, indium recovery depends on the knowledge of this technique and its development. This paper describes the solvent extraction knowledge for the indium recovery from aqueous solutions generated in mineral plants. The results for determination of the best experimental conditions to obtain a high indium concentration solution and minimum iron poisoning by solvent extraction with di (2-ethylhexyl)-phosphoric acid (D2EHPA) solubilized in isoparafin and exxsol has been presented. (author)

  7. Glycine-containing selective medium for isolation of Legionellaceae from environmental specimens.

    Science.gov (United States)

    Wadowsky, R M; Yee, R B

    1981-11-01

    Glycine, at a final concentration of 0.3%, has been shown to be an excellent selective agent for the isolation of Legionellaceae. Stock cultures of Legionella pneumophila were not inhibited on buffered charcoal-yeast extract agar containing the amino acid. Among the other Legionellaceae tested, only one of two strains of L. dumoffii and two of six strains of L. micdadei were appreciably inhibited. This medium permitted the isolation of L. pneumophila from environmental specimens with marked inhibition of many non-Legionellaceae bacteria. The selectivity of the medium was subsequently improved by the incorporation of vancomycin (5 microgram/ml) and polymyxin B (100 U/ml). This selective medium, glycine-vancomycin-polymyxin B agar, should facilitate the recovery of Legionellaceae from environmental sources.

  8. Initial results on computational performance of Intel Many Integrated Core (MIC) architecture: implementation of the Weather and Research Forecasting (WRF) Purdue-Lin microphysics scheme

    Science.gov (United States)

    Mielikainen, Jarno; Huang, Bormin; Huang, Allen H.

    2014-10-01

    Purdue-Lin scheme is a relatively sophisticated microphysics scheme in the Weather Research and Forecasting (WRF) model. The scheme includes six classes of hydro meteors: water vapor, cloud water, raid, cloud ice, snow and graupel. The scheme is very suitable for massively parallel computation as there are no interactions among horizontal grid points. In this paper, we accelerate the Purdue Lin scheme using Intel Many Integrated Core Architecture (MIC) hardware. The Intel Xeon Phi is a high performance coprocessor consists of up to 61 cores. The Xeon Phi is connected to a CPU via the PCI Express (PICe) bus. In this paper, we will discuss in detail the code optimization issues encountered while tuning the Purdue-Lin microphysics Fortran code for Xeon Phi. In particularly, getting a good performance required utilizing multiple cores, the wide vector operations and make efficient use of memory. The results show that the optimizations improved performance of the original code on Xeon Phi 5110P by a factor of 4.2x. Furthermore, the same optimizations improved performance on Intel Xeon E5-2603 CPU by a factor of 1.2x compared to the original code.

  9. La Multimodalidad del cómic: Una experiencia de lectura de imágenes en los primeros grados escolares

    Directory of Open Access Journals (Sweden)

    Adriana Chacón Méndez

    2015-07-01

    Full Text Available El presente artículo es el resultado de la investigación “Lectores de cómics: constructores de sentido”, una experiencia de lectura de imágenes que desde la perspectiva semiótica favorece la construcción de sentido de lo que se lee y posibilita la producción escrita en el contexto escolar. Esta investigación se realizó con estudiantes de segundo de primaria, en clase de lenguaje, en una institución educativa pública de Bogotá. El proyecto se desarrolló a través del diseño metodológico de la sistematización de experiencias que correlaciona los procesos de enseñanza y aprendizaje a través de prácticas pedagógicas que responden a nuevos modos de leer nuevos lenguajes, nuevas formas de representar y configurar la cultura.

  10. Collaborative Manufacturing for Small-Medium Enterprises

    Science.gov (United States)

    Irianto, D.

    2016-02-01

    Manufacturing systems involve decisions concerning production processes, capacity, planning, and control. In a MTO manufacturing systems, strategic decisions concerning fulfilment of customer requirement, manufacturing cost, and due date of delivery are the most important. In order to accelerate the decision making process, research on decision making structure when receiving order and sequencing activities under limited capacity is required. An effective decision making process is typically required by small-medium components and tools maker as supporting industries to large industries. On one side, metal small-medium enterprises are expected to produce parts, components or tools (i.e. jigs, fixture, mold, and dies) with high precision, low cost, and exact delivery time. On the other side, a metal small- medium enterprise may have weak bargaining position due to aspects such as low production capacity, limited budget for material procurement, and limited high precision machine and equipment. Instead of receiving order exclusively, a small-medium enterprise can collaborate with other small-medium enterprise in order to fulfill requirements high quality, low manufacturing cost, and just in time delivery. Small-medium enterprises can share their best capabilities to form effective supporting industries. Independent body such as community service at university can take a role as a collaboration manager. The Laboratory of Production Systems at Bandung Institute of Technology has implemented shared manufacturing systems for small-medium enterprise collaboration.

  11. Transcontinental mourning dove recovery

    Science.gov (United States)

    Sharp, Brian

    1971-01-01

    A Mourning Dove (Zenaida macroura) banded in New York has been reported shot in California. On 25 August 1969, near Palmyra (43°00' N, 77°10' W), New York Department of Environmental Conservation personnel placed U. S. Fish & Wildlife Service band 883-97279 on the leg of a hatching-year Mourning Dove of unknown sex. During the first weekend of the dove season in September 1970, Stan Solus (P.O. Box 594, Seiad Valley, California) recovered the band from a dove he shot in the Shasta Valley, Siskiyou County, California (41°30' N, 122°20' W). As Mr. Solus included the band with his reporting letter and, in response to my asking him for verification, reaffirmed his original information, the recovery has been accepted as authentic. I suggest this vagrancy may be explained by assuming that the inexperienced New York bird got emotionally involved with a western bird with which it shared winter quarters, perhaps in Mexico, and thus the following year ended up a flower child in California.

  12. Wastewater heat recovery apparatus

    Science.gov (United States)

    Kronberg, J.W.

    1992-09-01

    A heat recovery system is described with a heat exchanger and a mixing valve. A drain trap includes a heat exchanger with an inner coiled tube, baffle plate, wastewater inlet, wastewater outlet, cold water inlet, and preheated water outlet. Wastewater enters the drain trap through the wastewater inlet, is slowed and spread by the baffle plate, and passes downward to the wastewater outlet. Cold water enters the inner tube through the cold water inlet and flows generally upward, taking on heat from the wastewater. This preheated water is fed to the mixing valve, which includes a flexible yoke to which are attached an adjustable steel rod, two stationary zinc rods, and a pivoting arm. The free end of the arm forms a pad which rests against a valve seat. The rods and pivoting arm expand or contract as the temperature of the incoming preheated water changes. The zinc rods expand more than the steel rod, flexing the yoke and rotating the pivoting arm. The pad moves towards the valve seat as the temperature of the preheated water rises, and away as the temperature falls, admitting a variable amount of hot water to maintain a nearly constant average process water temperature. 6 figs.

  13. LHC Report: Rocky Recovery

    CERN Multimedia

    Mike Lamont for the LHC Team

    2011-01-01

    The last technical stop finished on Friday 8 July, but the machine returned to its pre-stop performance level over a week later.   Efficiency of LHC fills between 16 July and 20 July, 2011. The cryogenics team had the entire ring cold by Saturday morning and the usual post-technical stop tests with circulating beams started soon after. Unfortunately, they were interrupted by a major perturbation to CERN’s electrical network caused by an impressive thunderstorm that swept over the Pays de Gex. There were major knock-on effects, including the loss of cooling to the cryogenics and an inevitable recovery period once normal service had been re-established. The beams were circulating again by Tuesday afternoon and the post-technical stop checks continued, beefed up with further tests to address a number of issues related to the power cut.  Before the stop, the LHC had managed to get 1380 bunches per beam into collisions and the plan was to ramp back up relatively quickly to this leve...

  14. Heat recovery apparatus

    International Nuclear Information System (INIS)

    McFarland, I.

    1987-01-01

    Heat transfer is a living science and technical advances are constantly being made. However, in many cases, progress is limited by the equipment that is available on the market, rather than by knowledge of the heat transfer process. A case in point is the design of economizers: in such equipment a small quantity of water (with a relatively good heat transfer coefficient) is heated by a large quantity of low-pressure gas (with an inherently low heat transfer coefficient). As a first step in design finned tubing is used to lessen the discrepancy in coefficients. From this point, it becomes apparent that the equipment consists of a small number of tubes (to maintain good velocity on the water side) of considerable length (to provide sufficient area). In the process industries the base pressure, though low, may be in the region of 0.5 bar, and there is no convenient flue in which to place the heat recovery coil. It is therefore contained in a flat-sided enclosure, which is ill-fitted to pressure containment and is therefore reinforced with a plethora of structural sections. Such inelegant construction is quite common in North America; in Europe, cylindrical containments of vast size have been supplied for the same purposes. The real shortcoming is a successful marriage of different disciplines to produce reliable and efficient heat transfer equipment suitably contained

  15. Mic Check/Reality Check

    Directory of Open Access Journals (Sweden)

    Wanda Vrasti

    2012-03-01

    Full Text Available Over the past couple of months history has been unfolding with dizzying speed. The #occupy model of leaderless, demandless direct action, which in the beginning no one with only a slim understanding of how capitalism works thought could become anything more than a facile if charming jab at anti-corporate activism, has gone viral. Every morning we wake up to new reports about ‘occupying X’, where X can be anything from cities, campuses, boardrooms, buildings, highways, and public events, all the way to academic disciplines. What originally seemed like a romantic fantasy about temporary autonomous zones now feels like history. And no one likes to find themselves on thewrong side of history, especially not intellectuals, let alone intellectuals in the business of explaining global politics.

  16. Microbial Influenced Corrosion (MIC) Study

    Science.gov (United States)

    2012-05-23

    fumigatus Fusarium oxysporum Fungal Consortium Penicillium oxalicum Rhodoturula sp . Trichoderma sp . Dosed with microbes known to influence Control...Hypocrea jecorina (FI-1) Penicillium oxalicum (FI-12) – Pleosporacea sp . (FI-17) Rhodoturala mucilaginosa (FI-7) – Ustilago maydis (FI-13) T t S t• es...and Dirt Accumulation • Fungal Consortium – Aspergillus sp (FI-19) Aureobasidium pullulans (FI-16) – Fusarium oxysporum (FI-6) Fusarium sp . (FI-18

  17. Photonic-resonant left-handed medium

    International Nuclear Information System (INIS)

    Shen Jianqi

    2006-01-01

    A new scheme to realize simultaneously negative permittivity and permeability in a coherent atomic vapor medium (photonic-resonant material) via a coherent driving mechanism is suggested. It is verified that the atomic system coherently driven by a strong optical field will give rise to a negative refractive index in certain probe frequency ranges. One of the most remarkable features of the present scheme is such that a slab fabricated by the left-handed vapor medium is an ideal candidate for designing perfect lenses since the photonic-resonant atomic vapor cannot only exhibit an isotropic negative refractive index, but also provide a good impedance match at the air-medium interfaces

  18. Physical processes in the interstellar medium

    CERN Document Server

    Spitzer, Lyman

    2008-01-01

    Physical Processes in the Interstellar Medium discusses the nature of interstellar matter, with a strong emphasis on basic physical principles, and summarizes the present state of knowledge about the interstellar medium by providing the latest observational data. Physics and chemistry of the interstellar medium are treated, with frequent references to observational results. The overall equilibrium and dynamical state of the interstellar gas are described, with discussions of explosions produced by star birth and star death and the initial phases of cloud collapse leading to star formation.

  19. Recovery from cannabis use disorders: Abstinence versus moderation and treatment-assisted recovery versus natural recovery.

    Science.gov (United States)

    Stea, Jonathan N; Yakovenko, Igor; Hodgins, David C

    2015-09-01

    The present study of recovery from cannabis use disorders was undertaken with 2 primary objectives that address gaps in the literature. The first objective was to provide an exploratory portrait of the recovery process from cannabis use disorders, comparing individuals who recovered naturally with those who were involved in treatment. The second objective was to explore systematically the similarities and differences between abstinence and moderation recoveries. Adults who have recovered from a cannabis use disorder were recruited in the community (N = 119). The abstinence and treatment-assisted participants exhibited higher levels of lifetime cannabis problem severity than the moderation and natural recovery participants, respectively. As well, cognitive factors were identified as the most useful strategies for recovery (e.g., thinking about benefits and negative consequences of cannabis), followed by behavioral factors (e.g., avoidance of triggers for use and high-risk situations). Findings lend further support to the effectiveness of cognitive, motivational, and behavioral strategies as helpful actions and maintenance factors involved in the recovery process. The findings also generally support the idea that cannabis use disorders lie on a continuum of problem severity, with moderation and natural recoveries more likely to occur at the lower end of the continuum and abstinence and treatment-assisted recoveries more likely to occur at the upper end. (c) 2015 APA, all rights reserved).

  20. Course of Recovery from Alcoholism

    Science.gov (United States)

    Venner, Kamilla L.; Matzger, Helen; Forcehimes, Alyssa A.; Moos, Rudolf H.; Feldstein, Sarah W.; Willenbring, Mark L.; Weisner, Constance

    2010-01-01

    This article represents the proceedings of a symposium at the 2005 Research Society on Alcoholism meeting in Santa Barbara, California, organized and chaired by Kamilla L. Venner. This symposium integrated current empirical research on the course of recovery from alcoholism from multiple perspectives, an aim that is consistent with NIAAA's new focus on the process of recovery. The presentations and presenters were as follows: (1) The Role of Community Services and Informal Support on 7-Year Drinking Outcomes in Treated and Untreated Drinkers, by Helen Matzger; (2) The Sequence of Recovery Events in a Native American Sample, by Kamilla L. Venner; (3) Transformational Change in Recovery, by Alyssa A. Forcehimes; (4) Social Settings and Substance Use: Contextual Factors in Recovery, by Rudolf H. Moos; and (5) A Broader View of Change in Drinking Behavior, by discussant Mark L. Willenbring. A theme connecting the presentations was that treatment is but one discrete aspect to recovery and that sustained recovery is often influenced by an individual interaction with others within a social context. Collectively, presentations underscored the need to think more broadly about factors contributing to the remission of alcohol dependence. PMID:16737468

  1. From recovery values to recovery-oriented practice?

    DEFF Research Database (Denmark)

    Dalum, Helle; Pedersen, Inge Kryger; Cunningham, Harry

    2015-01-01

    Introduction: The recovery model has influenced mental health services and fostered new standards for best practice. However, knowledge about how mental health care professionals (HCPs) experience recoveryoriented programs is sparse. Aim/Question: This paper explores HCPs' experiences when...... facilitating a recovery-oriented rehabilitation program. The research question is howdo HCPs experience a change in their attitude and practicewhen applying recovery-oriented programs? Methods: This paper draws on semi-structured in-depth qualitative interviews conducted with 16 HCPs experienced...... in facilitating a recovery-oriented rehabilitation program in either the USA or Denmark. Results: Three themes emerged from the HCPs' reflections on changes in attitudes and practices: “Hopeful Attitude” captures a change in the HCPs' attitude toward a more positive view on the future for clients' living...

  2. Improved NGL recovery designs maximize operating flexibility and product recoveries

    International Nuclear Information System (INIS)

    Wilkinson, J.D.; Hudson, H.M.

    1992-01-01

    This paper reports that the historically cyclical nature in the market for ethane and propane has demonstrated the need for flexible natural gas liquids (NGL) recovery plants. NEwly developed and patented processes are now available which can provide ultra-high recovery of ethane (95%+) when demand for ethane is high and provide essentially complete ethane rejection without the normally concomitant reduction in propane recovery. This provides plant operators the flexibility to respond more readily to NGL market conditions, thus maximizing plant operating profits. The new process designs provide this flexibility without increasing utility requirements. In fact, utility consumption is often lower when compared to conventional designs. This same process technology can also be easily retrofit into existing plants with relatively quick payout of the modifications from both recovery and efficiency improvements

  3. Optimization of medium composition for apple rootstocks

    African Journals Online (AJOL)

    User

    2011-05-02

    May 2, 2011 ... Key words: Apple rootstocks, medium composition, multiplication rate, plant growth regulators (PGRs). ... be extrapolated with the same success for another .... Analysis System (SAS) software program (SAS Institute Inc. 1999).

  4. Jet multiplicity distributions: medium dependence in MLLA

    International Nuclear Information System (INIS)

    Armesto, Nestor; Pajares, Carlos; Quiroga-Arias, Paloma

    2009-01-01

    We study the medium dependence of the multiplicity distributions in the modified leading logarithmic approximation. We focus in the enhancement in the number of branchings as the partons travel trough a dense medium created in a heavy-ion collision. We study the effect of a higher number of splittings in some jet observables by introducing the medium as a constant (f med ) in the splitting functions. Having as our ansatz for the quark and gluon jets mean multiplicities left angle n G right angle =e γy and left angle n Q right angle =r -1 e γy , we study in an analytic approach the dependence with the medium (f med ) of the anomalous dimension (γ), the multiplicity ratio (r), and so the mean multiplicities. We also obtain the higher-order moments of the multiplicity distribution, what allows us to study its dispersion. (orig.)

  5. Optimization of medium composition for thermostable protease ...

    African Journals Online (AJOL)

    SERVER

    2008-04-17

    Apr 17, 2008 ... Optimization of the fermentation medium for maximization of thermostable neutral protease production by Bacillus sp. ..... Each contour curve represented an infinite number of combinations of two ..... Production in sea-water of.

  6. Fractional diffusion equation for heterogeneous medium

    International Nuclear Information System (INIS)

    Polo L, M. A.; Espinosa M, E. G.; Espinosa P, G.; Del Valle G, E.

    2011-11-01

    The asymptotic diffusion approximation for the Boltzmann (transport) equation was developed in 1950 decade in order to describe the diffusion of a particle in an isotropic medium, considers that the particles have a diffusion infinite velocity. In this work is developed a new approximation where is considered that the particles have a finite velocity, with this model is possible to describe the behavior in an anomalous medium. According with these ideas the model was obtained from the Fick law, where is considered that the temporal term of the current vector is not negligible. As a result the diffusion equation of fractional order which describes the dispersion of particles in a highly heterogeneous or disturbed medium is obtained, i.e., in a general medium. (Author)

  7. Small and medium power reactors 1987

    International Nuclear Information System (INIS)

    1987-12-01

    This TECDOC follows the publication of TECDOC-347 Small and Medium Power Reactors Project Initiation Study - Phase I published in 1985 and TECDOC-376 Small and Medium Power Reactors 1985 published in 1986. It is mainly intended for decision makers in Developing Member States interested in embarking on a nuclear power programme. It consists of two parts: 1) Guidelines for the Introduction of Small and Medium Power Reactors in Developing Countries. These Guidelines were established during the Advisory Group Meeting held in Vienna from 11 to 15 May 1987. Their purpose is to review key aspects relating to the introduction of Small and Medium Power Reactors in developing countries; 2) Up-dated Information on SMPR Concepts Contributed by Supplier Industries. According to the recommendations of the Second Technical Committee Meeting on SMPRs held in Vienna in March 1985, this part contains the up-dated information formerly published in Annex I of the above mentioned TECDOC-347. Figs

  8. Incompatibility of Contrast Medium and Trisodium Citrate

    International Nuclear Information System (INIS)

    Delcour, Christian; Bruninx, Guy

    2013-01-01

    To test the compatibility of trisodium citrate, a catheter lock solution, with iodinated contrast medium. Iohexol, iobitridol, iodixanol, ioxaglate, ioxithalamate, iomeprol, and iopromide were tested. In all tests, 2 ml of contrast medium were mixed with 2 ml of trisodium citrate solution. Iodixanol and ioxaglate provoked a highly viscous gluelike precipitation when mixed with trisodium citrate. A brief transient precipitate was observed with iohexol, iomeprol, and ioxithalamate. Permanent precipitation occurred with iobitridol and iopromide. One must be aware of the potential for precipitation when contrast medium is mixed with trisodium citrate solution. Before trisodium citrate solution is injected, the catheter should be thoroughly flushed with saline if a contrast medium has previously been injected through it.

  9. Study of niobium corrosion in alkaline medium

    International Nuclear Information System (INIS)

    Almeida, S.H. de.

    1987-01-01

    A comparative study of niobium electrochemical behaviour in NaOH and KOH solution, with concentrations between 0,5 and 6,1M is presented. The studies were done through electrochemicals assays, consisting in the corrosion potential and anodic and cathodic polarization curves, complemented by loss of mass experiments. The niobium anodic behaviour in alkaline medium is characterized by passivation occurrence, with a stable film formation. The Na oH solution in alkaline medium are more corrosible to niobium than the KOH solution. The loss of mass assays showed that the corrosion velocit is more dependente of hydroxide concentration in KOH medium than the NaOH medium. (C.G.C.) [pt

  10. Small and Medium Enterprises and Biopharmaceutical Innovations ...

    African Journals Online (AJOL)

    Erah

    Benin City, 300001 Nigeria. All rights ... are challenges facing African Small and Medium Enterprises (SMEs) in biopharmaceutical industry, the ... Network for Drug and Diagnostics recognizes .... functionality is in place, integration into the.

  11. Sharing perspectives on English-medium instruction

    CERN Document Server

    Ackerley, Katherine; Helm, Francesca

    2017-01-01

    This volume gives voice to the views and experiences of researchers, lecturers, administrative staff, teacher trainers and students with regard to the implementation of English-medium instruction in a public university based in the north-east of Italy.

  12. Medium Effects in Reactions with Rare Isotopes

    International Nuclear Information System (INIS)

    Bertulani, C A; Karakoç, M

    2012-01-01

    We discuss medium effects in knockout reactions with rare isotopes of weakly-bound nuclei at intermediate energies. We show that the poorly known corrections may lead to sizable modifications of knockout cross sections and momentum dsitributions.

  13. Effective medium theory principles and applications

    CERN Document Server

    Choy, Tuck C

    2015-01-01

    Effective medium theory dates back to the early days of the theory of electricity. Faraday in 1837 proposed one of the earliest models for a composite metal-insulator dielectric and around 1870 Maxwell and later Garnett (1904) developed models to describe a composite or mixed material medium. The subject has been developed considerably since and while the results are useful for predicting materials performance, the theory can also be used in a wide range of problems in physics and materials engineering. This book develops the topic of effective medium theory by bringing together the essentials of both the static and the dynamical theory. Electromagnetic systems are thoroughly dealt with, as well as related areas such as the CPA theory of alloys, liquids, the density functional theory etc., with applications to ultrasonics, hydrodynamics, superconductors, porous media and others, where the unifying aspects of the effective medium concept are emphasized. In this new second edition two further chapters have been...

  14. Small and medium power reactors 1987

    Science.gov (United States)

    1987-12-01

    This TECDOC follows the publication of TECDOC-347: Small and Medium Power Reactors (SMPR) Project Initiation Study, Phase 1, published in 1985 and TECDOC-376: Small and Medium Power Reactors 1985 published in 1986. It is mainly intended for decision makers in Developing Member States interested in embarking on a nuclear power program. It consists of two parts: (1) guidelines for the introduction of small and medium power reactors in developing countries. These Guidelines were established during the Advisory Group Meeting held in Vienna from 11 to 15 May 1987. Their purpose is to review key aspects relating to the introduction of small and medium power reactors in developing countries; (2) up-dated information on SMPR Concepts Contributed by Supplier Industries. According to the recommendations of the Second Technical Committee Meeting on SMPRs held in Vienna in March 1985, this part contains the up-dated information formerly published in Annex 1 of the above mentioned TECDOC-347.

  15. Whooping crane recovery plan

    Science.gov (United States)

    Olsen, David L.; Blankenship, David R.; Irby, Harold D.; Erickson, Ray C.; Lock, Ross; Drewien, Roderick C.; Smith, Lawrence S.; Derrickson, Scott R.

    1980-01-01

    This plan has been prepared under the authority of the Endangered Species Act of 1973 and subsequent amendments. The Plan is designed to provide decision makers with an orderly set of events which, if carried out to a successful completion, will result in changing the status of the species from the endangered to the threatened level. It must be recognized that this Plan has been prepared 40 years after attempts to preserve the species began. As such, it covers events that have taken place, that are taking place, and that need to take place. The Plan, therefore, not only compiles in one place all whooping crane management and research efforts which are underway, but also proposes additional efforts needed for the recovery of the whooping crane. The Plan also establishes funding evels, time schedules, and priorities for each management and research effort.The Plan is organized into three parts. the first part includes an account of the whooping crane's history, biology, present status, and the factors believed to have resulted in its endangered status. Also included in this part is a synopsis of research and management activities that have taken place through 1978.The second part is a step-down pan wherein all existing and needed research and management efforts are organized into an orderly set of events. The prime objective is to move the whooping crane to non-endangered status. Minimum requirements for the attainment of this objective are the increase of the historical Wood Buffalo-Aransas population to at least 40 nesting pairs and the establishment of at least two additional, separate, and self-sustaining populations consisting of at least 20 nesting pairs each.the third part identifies the responsibility, time schedule, and cost for each element of the step-down plan.

  16. Recovery during radiation mutagenesis

    International Nuclear Information System (INIS)

    Deen, D.F.; Shaw, E.I.

    1976-01-01

    Many variables (e.g. cell inoculum size, mutagen dose, expression time, and concentration of the selective agent) are known to affect the induced mutation frequency obtained in cultured mammalian cells. The authors have studied the effects of several parameters on the frequency of radiation-induced resistance to 8-azaguanine in asynchronous V79-171B hamster cells. Inoculation with 10 5 cells was followed by graded doses of radiation, expression times were optimized to maximize mutation frequency, and then the treated cells were challenged with 8-azaguanine for ten days. The optimal expression times which maximized mutation frequency were dose dependent and are in the range of 14-24, 24, and 24-36 hours respectively for doses of 250, 40 and 800 rads. A time interval of 24 hours between two 250-rad fractions resulted in a mutation frequency smaller than that obtained from administration of a single 500-rad dose. With 36 hours between halves of the dose, the induced mutation frequency was an order of magnitude lower than that produced by a single dose and actually below the unirradiated (spontaneous) frequency. Maintenance of cells after irradation first at 18 0 C for 24 hours, and then allowance of expression at 37 0 C for 24 hours, increased both the spontaneous and induced mutation frequency. A one-hour postirradiation balanced salt-solution treatment did not affect the number of spontaneous mutants that arose, but reduced the number of induced mutants. Thus, the balanced salt treatment lowers the induced mutation frequency about a factor of two. The possible significance of these results are discussed with respect to the role of radiation repair mechanisms during mutagenesis, and to recovery at low dose rates. A working hypothesis is advanced to explain the possible mechanism which causes expression time to vary as a function of the dose of mutagen. (author)

  17. General introduction and recovery factors

    Science.gov (United States)

    Verma, Mahendra K.

    2017-07-17

    IntroductionThe U.S. Geological Survey (USGS) compared methods for estimating an incremental recovery factor (RF) for the carbon dioxide enhanced oil recovery (CO2-EOR) process involving the injection of CO2 into oil reservoirs. This chapter first provides some basic information on the RF, including its dependence on various reservoir and operational parameters, and then discusses the three development phases of oil recovery—primary, second­ary, and tertiary (EOR). It ends with a brief discussion of the three approaches for estimating recovery factors, which are detailed in subsequent chapters.

  18. Technology for recovery of byproducts

    International Nuclear Information System (INIS)

    Van Tuyl, H.H.

    1983-02-01

    In this paper, a byproduct is considered to be any product from a nuclear fuel reprocessing plant other than the principal products of uranium and plutonium. Those which have been recovered on a large scale include: 237 Np, 90 Sr, 137 Cs, 85 Kr, 147 Pm, 241 Am, 244 Cm, and 144 Ce. Other byproducts which have been recovered in small amounts during development efforts are: Tc, Ru, Rh, Pd, and Xe. This paper reviews the byproducts of interest, compares and contrasts byproduct recovery with waste management, describes current and past byproduct recovery operations, development status of alternative processes, and bases for selection among alternative processes in developing an integrated byproduct recovery plant

  19. Switching power converters medium and high power

    CERN Document Server

    Neacsu, Dorin O

    2013-01-01

    An examination of all of the multidisciplinary aspects of medium- and high-power converter systems, including basic power electronics, digital control and hardware, sensors, analog preprocessing of signals, protection devices and fault management, and pulse-width-modulation (PWM) algorithms, Switching Power Converters: Medium and High Power, Second Edition discusses the actual use of industrial technology and its related subassemblies and components, covering facets of implementation otherwise overlooked by theoretical textbooks. The updated Second Edition contains many new figures, as well as

  20. DYNAMIC DEFORMATION THE VISCOELASTIC TWOCOMPONENT MEDIUM

    Directory of Open Access Journals (Sweden)

    V. S. Polenov

    2015-01-01

    Full Text Available Summary. In the article are scope harmonious warping of the two-component medium, one component which are represent viscoelastic medium, hereditary properties which are described by the kernel aftereffect Abel integral-differential ratio BoltzmannVolterr, while second – compressible liquid. Do a study one-dimensional case. Use motion equation of two-component medium at movement. Look determination system these equalization in the form of damped wave. Introduce dimensionless coefficient. Combined equations happen to homogeneous system with complex factor relatively waves amplitude in viscoelastic component and in fluid. As a result opening system determinant receive biquadratic equation. Elastic operator express through kernel aftereffect Abel for space Fourier. With the help transformation and symbol series biquadratic equation reduce to quadratic equation. Come to the conclusion that in two-component viscoelastic medium exist two mode sonic waves. As a result solution of quadratic equation be found description advance of waves sonic in viscoelastic two-component medium, which physical-mechanical properties represent complex parameter. Velocity determination advance of sonic waves, attenuation coefficient, mechanical loss tangent, depending on characteristic porous medium and circular frequency formulas receive. Graph dependences of description advance of waves sonic from the temperature logarithm and with the fractional parameter γ are constructed.

  1. Evaluation of the effects of storage in two different swab fabrics and under three different transport conditions on recovery of aerobic and anaerobic bacteria

    NARCIS (Netherlands)

    Roelofsen, E.; Leeuwen, M. van; Meijer-Severs, G.J.; Wilkinson, M.H.F.; Degener, J.E.

    Recovery of six anaerobic and five aerobic pathogens from viscose swabs and polyurethane swabs (Culturette EZ) was evaluated quantitatively, and transport in aerobic dry tubes, aerobic Amies transport medium (Transwab), and anaerobic universal transport medium (Port-a-Cul) was compared. The

  2. Recovery and purification of ethylene

    Science.gov (United States)

    Reyneke, Rian [Katy, TX; Foral, Michael J [Aurora, IL; Lee, Guang-Chung [Houston, TX; Eng, Wayne W. Y. [League City, TX; Sinclair, Iain [Warrington, GB; Lodgson, Jeffery S [Naperville, IL

    2008-10-21

    A process for the recovery and purification of ethylene and optionally propylene from a stream containing lighter and heavier components that employs an ethylene distributor column and a partially thermally coupled distributed distillation system.

  3. The Vessel Schedule Recovery Problem

    DEFF Research Database (Denmark)

    Brouer, Berit Dangaard; Plum, Christian Edinger Munk; Vaaben, Bo

    Maritime transportation is the backbone of world trade and is accountable for around 3% of the worlds CO2 emissions. We present the Vessel Schedule Recovery Problem (VSRP) to evaluate a given disruption scenario and to select a recovery action balancing the trade off between increased bunker cons...... consumption and the impact on the remaining network and the customer service level. The model is applied to 4 real cases from Maersk Line. Solutions are comparable or superior to those chosen by operations managers. Cost savings of up to 58% may be achieved.......Maritime transportation is the backbone of world trade and is accountable for around 3% of the worlds CO2 emissions. We present the Vessel Schedule Recovery Problem (VSRP) to evaluate a given disruption scenario and to select a recovery action balancing the trade off between increased bunker...

  4. Pacific Coastal Salmon Recovery Fund

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Congress established the Pacific Coastal Salmon Recovery Fund (PCSRF) to monitor the restoration and conservation of Pacific salmon and steelhead populations and...

  5. FEMA Disaster Recovery Centers - KML

    Data.gov (United States)

    Department of Homeland Security — This is a KML file for FEMA's Disaster Recovery Centers (DRC). A DRC is a readily accessible facility or mobile office set up by FEMA where applicants may go for...

  6. Recovery Time for Sports Concussions

    Science.gov (United States)

    ... this issue Health Capsule Recovery Time for Sports Concussions En español Send us your comments Scientists look ... an athlete to return to play after a concussion. Paul Burns/Blend Images/Thinkstock A brain injury- ...

  7. Many-integrated core (MIC) technology for accelerating Monte Carlo simulation of radiation transport: A study based on the code DPM

    Science.gov (United States)

    Rodriguez, M.; Brualla, L.

    2018-04-01

    Monte Carlo simulation of radiation transport is computationally demanding to obtain reasonably low statistical uncertainties of the estimated quantities. Therefore, it can benefit in a large extent from high-performance computing. This work is aimed at assessing the performance of the first generation of the many-integrated core architecture (MIC) Xeon Phi coprocessor with respect to that of a CPU consisting of a double 12-core Xeon processor in Monte Carlo simulation of coupled electron-photonshowers. The comparison was made twofold, first, through a suite of basic tests including parallel versions of the random number generators Mersenne Twister and a modified implementation of RANECU. These tests were addressed to establish a baseline comparison between both devices. Secondly, through the p DPM code developed in this work. p DPM is a parallel version of the Dose Planning Method (DPM) program for fast Monte Carlo simulation of radiation transport in voxelized geometries. A variety of techniques addressed to obtain a large scalability on the Xeon Phi were implemented in p DPM. Maximum scalabilities of 84 . 2 × and 107 . 5 × were obtained in the Xeon Phi for simulations of electron and photon beams, respectively. Nevertheless, in none of the tests involving radiation transport the Xeon Phi performed better than the CPU. The disadvantage of the Xeon Phi with respect to the CPU owes to the low performance of the single core of the former. A single core of the Xeon Phi was more than 10 times less efficient than a single core of the CPU for all radiation transport simulations.

  8. The widely used ATB FUNGUS 3 automated readings in China and its misleading high MICs of Candida spp. to azoles: challenges for developing countries' clinical microbiology labs.

    Science.gov (United States)

    Zhang, Li; Wang, He; Xiao, Meng; Kudinha, Timothy; Mao, Lei-Li; Zhao, Hao-Ran; Kong, Fanrong; Xu, Ying-Chun

    2014-01-01

    The rapid development in the clinical microbiology diagnostic assays presents more challenges for developing countries than for the developed world, especially in the area of test validation before the introduction of new tests. Here we report on the misleading high MICs of Candida spp. to azoles using the ATB FUNGUS 3 (bioMérieux, La Balme-les Grottes, France) with automated readings in China to highlight the dangers of introducing a diagnostic assay without validation. ATB FUNGUS 3 is the most commonly used commercial antifungal susceptibility testing method in China. An in-depth analysis of data showed higher levels of resistance to azoles when ATB FUNGUS 3 strips were read automatically than when read visually. Based on this finding, the performance of ATB FUNGUS 3, read both visually and automatically, was evaluated by testing 218 isolates of five clinically important Candida species, using broth microdilution (BMD) following CLSI M27-A3 as the gold-standard. The overall essential agreement (EA) between ATB visual readings and BMD was 99.1%. In contrast, the ATB automated readings showed higher discrepancies with BMD, with overall EA of 86.2%, and specifically lower EA was observed for fluconazole (80.7%), voriconazole (77.5%), and itraconazole (73.4%), which was most likely due to the trailing effect of azoles. The major errors in azole drug susceptibilities by ATB automated readings is a concern in China that can result in misleading clinical antifungal drug selection and pseudo high rates of antifungal resistance. Therefore, the ATB visual reading is generally recommended. In the meantime, we propose a practical algorithm to be followed for ATB FUNGUS 3 antifungal susceptibility for Candida spp. before the improvement in the automated reading system.

  9. The widely used ATB FUNGUS 3 automated readings in China and its misleading high MICs of Candida spp. to azoles: challenges for developing countries' clinical microbiology labs.

    Directory of Open Access Journals (Sweden)

    Li Zhang

    Full Text Available The rapid development in the clinical microbiology diagnostic assays presents more challenges for developing countries than for the developed world, especially in the area of test validation before the introduction of new tests. Here we report on the misleading high MICs of Candida spp. to azoles using the ATB FUNGUS 3 (bioMérieux, La Balme-les Grottes, France with automated readings in China to highlight the dangers of introducing a diagnostic assay without validation. ATB FUNGUS 3 is the most commonly used commercial antifungal susceptibility testing method in China. An in-depth analysis of data showed higher levels of resistance to azoles when ATB FUNGUS 3 strips were read automatically than when read visually. Based on this finding, the performance of ATB FUNGUS 3, read both visually and automatically, was evaluated by testing 218 isolates of five clinically important Candida species, using broth microdilution (BMD following CLSI M27-A3 as the gold-standard. The overall essential agreement (EA between ATB visual readings and BMD was 99.1%. In contrast, the ATB automated readings showed higher discrepancies with BMD, with overall EA of 86.2%, and specifically lower EA was observed for fluconazole (80.7%, voriconazole (77.5%, and itraconazole (73.4%, which was most likely due to the trailing effect of azoles. The major errors in azole drug susceptibilities by ATB automated readings is a concern in China that can result in misleading clinical antifungal drug selection and pseudo high rates of antifungal resistance. Therefore, the ATB visual reading is generally recommended. In the meantime, we propose a practical algorithm to be followed for ATB FUNGUS 3 antifungal susceptibility for Candida spp. before the improvement in the automated reading system.

  10. La industria del cómic en España: radiografía de ¿un mito o una realidad?

    Directory of Open Access Journals (Sweden)

    Pons, Álvaro M.

    2011-09-01

    Full Text Available In spite of the importance of figures referred to published titles, or number of copies printed, which help to set publishing strategies and to really know the comic situation in Spain, there are no liable data. We are giving in this article, some enlightening data along with some explanations related to the evolution of the market from 2001 to 2009. The different titles are grouped considering the place they come from (Europe, Asia, United States…, along with their format (album, book, magazine, comic-book…. Using all this information, we can deduce evolution lines, tendencies, futures perspectives in an industry that, despite its precariousness, is facing an increasing number of copies sold and a progressive settlement in the Spanish publishing world.

    A pesar de la importancia que revestiría para establecer estrategias editoriales y para un mejor conocimiento de la situación del cómic en España, no existen cifras fiables sobre títulos publicados y cifras de tiradas. En este artículo se proporcionan algunos datos aclaradores al respecto. Se ofrece una evolución de nuestro mercado desde 2001 a 2009. Se agrupan los diversos títulos por lugar de procedencia (Europa, Asia, Estados Unidos…, así como por formatos (álbum, libro, revista, comic-book…. De todo ello se desprenden líneas evolutivas, tendencias y perspectivas de futuro de una industria que, a pesar de su precariedad, conoce un aumento de las ventas y un progresivo asentamiento en el panorama de la edición española.

  11. Uncovering Recovery: The Resistible Rise of Recovery and Resilience

    Directory of Open Access Journals (Sweden)

    David Harper

    2012-10-01

    Full Text Available Discourses of recovery and resilience have risen to positions of dominance in the mental health field. Models of recovery and resilience enjoy purchase, in both policy and practice, across a range of settings from self-described psychiatric survivors through to mental health charities through to statutory mental health service providers. Despite this ubiquity, there is confusion about what recovery means. In this article we problematize notions of recovery and resilience, and consider what, if anything, should be recovered from these concepts. We focus on three key issues, i individualization, ii the persistence of a deficit model, and iii collective approaches to recovery. Through documentary analysis we consider these issues across third sector organizations, and public and mental health policy. Firstly, definitional debates about recovery reflect wider ideological debates about the nature of mental health. The vagueness of these concepts and implicit assumptions inherent in dominant recovery and resilience discourses render them problematic because they individualize what are social problems. Secondly, these discourses, despite being seen as inherently liberatory are conceptually dependent on a notion of deficit in that talk of “positives” and “strengths” requires the existence of “negatives” and “weaknesses” for these concepts to make sense.  We argue that this does little to substantially transform dominant understandings of psychological distress. Thirdly, these issues combine to impact upon the progressive potential of recovery. It comes to be seen as an individualistic experiential narrative accompaniment to medical understandings where the structural causes of distress are obscured. This in turn impacts upon the potential for recovery to be used to explore more collective, political aspects of emotional distress. Drawing on the work of Fraser, we use this critique to characterize “recovery” as a “struggle for

  12. Carbon dioxide for enhanced oil recovery in Canada

    Energy Technology Data Exchange (ETDEWEB)

    McDonald, S.; Manbybura, F.; Sparks, N.

    1985-01-01

    This paper examines the potential for carbon dioxide as a major miscible solvent in Canada and describes Shell Canada's carbon dioxide exploration efforts over the last few years. Enhanced oil recovery, specifically miscible flooding, has been recognized as a technically and economically feasible method for adding reserves and productive capacity to Canada's light and medium oil. The fiscal regime has been altered by both the federal and provincial governments to encourage miscible flooding development. As a result many projects have been initiated with others being evaluated and designed. This paper analyzes the history and the direction of miscible flooding in the United States, where carbon dioxide is becoming the predominant miscible solvent. The potential for future use of carbon dioxide in Canada is specifically addressed: potential oil recovery solvent supply, and economics. Shell's carbon dioxide exploration play currently underway is also discussed.

  13. Recovery of uranium from uranium bearing black shale

    International Nuclear Information System (INIS)

    Das, Amrita; Yadav, Manoj; Singh, Ajay K.

    2016-01-01

    Black shale is the unconventional resource of uranium. Recovery of uranium from black shale has been carried out by the following steps: i) size reduction, ii) leaching of uranium in the aqueous medium, iii) fluoride ion removal, iv) solvent extraction of uranium from the aqueous leach solution, v) scrubbing of the loaded solvent after extraction to remove impurities as much as possible and vi) stripping of uranium from the loaded organic into the aqueous phase. Leaching of black shale has been carried out in hydrochloric acid. Free acidity of the leach solution has been determined by potentiometric titration method. Removal of fluoride ions has been done using sodium chloride. Solvent extraction has been carried out by both tributyl phosphate and alamine-336 as extractants. Scrubbing has been tried with oxalic acid and sulphuric acid. Stripping with sodium carbonate solution has been carried out. Overall recovery of uranium is 95%. (author)

  14. Biological opportunities for metal recovery

    International Nuclear Information System (INIS)

    Holmes, D.S.; Debus, S.H.

    1991-01-01

    An overview is presented of existing biological technologies for the recovery of copper and uranium. Engineering and biological challenges and opportunities in these areas are discussed. New opportunities for the bio oxidation of refractory goal ore are described. Techniques for the development of new strains of microorganisms for commercial metal recovery applications are discussed with special reference to the use of genetic manipulation for bacterial strain improvement. (author)

  15. Cognitive performance and aphasia recovery.

    Science.gov (United States)

    Fonseca, José; Raposo, Ana; Martins, Isabel Pavão

    2018-03-01

    Objectives This study assessed cognitive performance of subjects with aphasia during the acute stage of stroke and evaluated how such performance relates to recovery at 3 months. Materials & methods Patients with aphasia following a left hemisphere stroke were evaluated during the first (baseline) and the fourth-month post onset. Assessment comprised non-verbal tests of attention/processing speed (Symbol Search, Cancelation Task), executive functioning (Matrix Reasoning, Tower of Hanoi, Clock Drawing, Motor Initiative), semantic (Camel and Cactus Test), episodic and immediate memory (Memory for Faces Test, 5 Objects Memory Test, and Spatial Span. Recovery was measured by the Token Test score at 3 months. The impact of baseline performance on recovery was evaluated by logistic regression adjusting for age, education, severity of aphasia and the Alberta Stroke Program Early CT (ASPECT) score. Results Thirty-nine subjects (with a mean of 66.5 ± 10.6 years of age, 17 men) were included. Average baseline cognitive performance was within normal range in all tests except in memory tests (semantic, episodic and immediate memory) for which scores were ≤-1.5sd. Subjects with poor aphasia recovery (N = 27) were older and had fewer years of formal education but had identical ASPECT score compared to those with favorable recovery. Considering each test individually, the score obtained on the Matrix Reasoning test was the only one to predict aphasia recovery (Exp(B)=24.085 p = 0.038). Conclusions The Matrix Reasoning Test may contribute to predict aphasia recovery. Cognitive performance is a measure of network disruption but may also indicate the availability of recovery strategies.

  16. Performance experimental investigation of novel multifunctional nanohybrids on enhanced oil recovery

    Science.gov (United States)

    Gharibshahi, Reza; Jafari, Arezou; Omidkhah, Mohammadreza; Nezhad, Javad Razavi

    2018-01-01

    The unique characteristics of materials at the nanoscale make them a good candidate to use in the enhanced oil recovery (EOR) processes. Therefore, in this study, the effect of functionalized multi-walled carbon nanotube/silica nanohybrids on the oil recovery factor is investigated experimentally and nanofluids were injected into a glass micromodel for the first time. The nanohybrids synthesized by using sol-gel method. Micromodels as microscale apparatuses considered as 2D porous medium. Because they enable visual observation of phase displacement behavior at the pore scale. Distillated water used as the dispersion medium of nanoparticles for nanofluids preparation. A series of runs designed for flooding operations included water injection, carbon nanotube/water injection and two nanohybrids with different weight of MWCNT to the overall weight of the nanohybrid structure (10% and 70%) into the distilled water. Also, the oil recovery factor was considered as the goal parameter to compare the results. It has been found that functionalized multi-walled carbon nanotube/silica nanohybrids have a great potential in enhanced oil recovery processes. Results showed that addition of nanohybrids into distillate water causes enhancement of sweep efficiency. In other words, the fingering effect decreases and higher surface of porous medium is in contact with the injected fluid. So the higher amount of oil can produce from the porous medium consequently. By injecting nanofluid with 0.1 wt. % of carbon nanotube, the oil recovery factor increases about 11 % in comparison with water injection alone. Also by increasing the weight of MWCNT to the overall weight of the nanohybrid structure from 10% to 70%, the oil recovery factor increases from 35% to 39%.

  17. On the optimal design of the disassembly and recovery processes.

    Science.gov (United States)

    Xanthopoulos, A; Iakovou, E

    2009-05-01

    This paper tackles the problem of the optimal design of the recovery processes of the end-of-life (EOL) electric and electronic products, with a special focus on the disassembly issues. The objective is to recover as much ecological and economic value as possible, and to reduce the overall produced quantities of waste. In this context, a medium-range tactical problem is defined and a novel two-phased algorithm is presented for a remanufacturing-driven reverse supply chain. In the first phase, we propose a multicriteria/goal-programming analysis for the identification and the optimal selection of the most 'desirable' subassemblies and components to be disassembled for recovery, from a set of different types of EOL products. In the second phase, a multi-product, multi-period mixed-integer linear programming (MILP) model is presented, which addresses the optimization of the recovery processes, while taking into account explicitly the lead times of the disassembly and recovery processes. Moreover, a simulation-based solution approach is proposed for capturing the uncertainties in reverse logistics. The overall approach leads to an easy-to-use methodology that could support effectively middle level management decisions. Finally, the applicability of the developed methodology is illustrated by its application on a specific case study.

  18. On the optimal design of the disassembly and recovery processes

    International Nuclear Information System (INIS)

    Xanthopoulos, A.; Iakovou, E.

    2009-01-01

    This paper tackles the problem of the optimal design of the recovery processes of the end-of-life (EOL) electric and electronic products, with a special focus on the disassembly issues. The objective is to recover as much ecological and economic value as possible, and to reduce the overall produced quantities of waste. In this context, a medium-range tactical problem is defined and a novel two-phased algorithm is presented for a remanufacturing-driven reverse supply chain. In the first phase, we propose a multicriteria/goal-programming analysis for the identification and the optimal selection of the most 'desirable' subassemblies and components to be disassembled for recovery, from a set of different types of EOL products. In the second phase, a multi-product, multi-period mixed-integer linear programming (MILP) model is presented, which addresses the optimization of the recovery processes, while taking into account explicitly the lead times of the disassembly and recovery processes. Moreover, a simulation-based solution approach is proposed for capturing the uncertainties in reverse logistics. The overall approach leads to an easy-to-use methodology that could support effectively middle level management decisions. Finally, the applicability of the developed methodology is illustrated by its application on a specific case study

  19. Total Value of Phosphorus Recovery.

    Science.gov (United States)

    Mayer, Brooke K; Baker, Lawrence A; Boyer, Treavor H; Drechsel, Pay; Gifford, Mac; Hanjra, Munir A; Parameswaran, Prathap; Stoltzfus, Jared; Westerhoff, Paul; Rittmann, Bruce E

    2016-07-05

    Phosphorus (P) is a critical, geographically concentrated, nonrenewable resource necessary to support global food production. In excess (e.g., due to runoff or wastewater discharges), P is also a primary cause of eutrophication. To reconcile the simultaneous shortage and overabundance of P, lost P flows must be recovered and reused, alongside improvements in P-use efficiency. While this motivation is increasingly being recognized, little P recovery is practiced today, as recovered P generally cannot compete with the relatively low cost of mined P. Therefore, P is often captured to prevent its release into the environment without beneficial recovery and reuse. However, additional incentives for P recovery emerge when accounting for the total value of P recovery. This article provides a comprehensive overview of the range of benefits of recovering P from waste streams, i.e., the total value of recovering P. This approach accounts for P products, as well as other assets that are associated with P and can be recovered in parallel, such as energy, nitrogen, metals and minerals, and water. Additionally, P recovery provides valuable services to society and the environment by protecting and improving environmental quality, enhancing efficiency of waste treatment facilities, and improving food security and social equity. The needs to make P recovery a reality are also discussed, including business models, bottlenecks, and policy and education strategies.

  20. Global patterns of drought recovery

    Energy Technology Data Exchange (ETDEWEB)

    Schwalm, Christopher R.; Anderegg, William R. L.; Michalak, Anna M.; Fisher, Joshua B.; Biondi, Franco; Koch, George; Litvak, Marcy; Ogle, Kiona; Shaw, John D.; Wolf, Adam; Huntzinger, Deborah N.; Schaefer, Kevin; Cook, Robert; Wei, Yaxing; Fang, Yuanyuan; Hayes, Daniel; Huang, Maoyi; Jain, Atul; Tian, Hanqin

    2017-08-09

    Drought is a recurring multi-factor phenomenon with major impacts on natural and human systems1-3. Drought is especially important for land carbon sink variability, influencing climate regulation of the terrestrial biosphere4. While 20th Century trends in drought regime are ambiguous, “more extreme extremes” as well as more frequent and severe droughts3,7 are expected in the 21st Century. Recovery time, the length of time an ecosystem requires to revert to its pre-drought functional state, is a critical metric of drought impact. Yet the spatiotemporal patterning and controls of drought recovery are largely unknown. Here we use three distinct global datasets of gross primary productivity to show that across diverse terrestrial ecosystems drought recovery times are driven by biological productivity and biodiversity, with drought length and severity of secondary importance. Recovery time, especially for extreme droughts, and the areal extent of ecosystems in recovery from drought generally increase over the 20th Century, supporting an increase globally in drought impact8. Our results indicate that if future Anthropocene droughts become more widespread as expected, that droughts will become more frequent relative to recovery time. This increases the risk of entering a new regime where vegetation never recovers to its original state and widespread degradation of the land carbon sink ensues.

  1. Overview of medium heterogeneity and transport processes

    International Nuclear Information System (INIS)

    Tsang, Y.; Tsang, C.F.

    1993-11-01

    Medium heterogeneity can have significant impact on the behavior of solute transport. Tracer breakthrough curves from transport in a heterogeneous medium are distinctly different from that in a homogeneous porous medium. Usually the shape of the breakthrough curves are highly non-symmetrical with a fast rise at early times and very long tail at late times, and often, they consist of multiple peaks. Moreover, unlike transport in a homogeneous medium where the same transport parameters describe the entire medium, transport through heterogeneous media gives rise to breakthrough curves which have strong spatial dependence. These inherent characteristics of transport in heterogeneous medium present special challenge to the performance assessment of a potential high level nuclear waste repository with respect to the possible release of radio nuclides to the accessible environment. Since an inherently desirable site characteristic for a waste repository is that flow and transport should be slow, then transport measurements in site characterization efforts will necessarily be spatially small and temporally short compare to the scales which are of relevance to performance assessment predictions. In this paper we discuss the role of medium heterogeneity in site characterization and performance assessment. Our discussion will be based on a specific example of a 3D heterogeneous stochastic model of a site generally similar to, the Aespoe Island, the site of the Hard Rock Laboratory in Southern Sweden. For our study, alternative 3D stochastic fields of hydraulic conductivities conditioned on ''point'' measurements shall be generated. Results of stochastic flow and transport simulations would be used to address the issues of (1) the relationship of tracer breakthrough with the structure of heterogeneity, and (2) the inference from small scale testing results to large scale and long term predictions

  2. Effect of culture medium, host strain and oxygen transfer on recombinant Fab antibody fragment yield and leakage to medium in shaken E. coli cultures

    Science.gov (United States)

    2013-01-01

    Background Fab antibody fragments in E. coli are usually directed to the oxidizing periplasmic space for correct folding. From periplasm Fab fragments may further leak into extracellular medium. Information on the cultivation parameters affecting this leakage is scarce, and the unpredictable nature of Fab leakage is problematic regarding consistent product recovery. To elucidate the effects of cultivation conditions, we investigated Fab expression and accumulation into either periplasm or medium in E. coli K-12 and E. coli BL21 when grown in different types of media and under different aeration conditions. Results Small-scale Fab expression demonstrated significant differences in yield and ratio of periplasmic to extracellular Fab between different culture media and host strains. Expression in a medium with fed-batch-like glucose feeding provided highest total and extracellular yields in both strains. Unexpectedly, cultivation in baffled shake flasks at 150 rpm shaking speed resulted in higher yield and accumulation of Fabs into culture medium as compared to cultivation at 250 rpm. In the fed-batch medium, extracellular fraction in E. coli K-12 increased from 2-17% of total Fab at 250 rpm up to 75% at 150 rpm. This was partly due to increased lysis, but also leakage from intact cells increased at the lower shaking speed. Total Fab yield in E. coli BL21 in glycerol-based autoinduction medium was 5 to 9-fold higher at the lower shaking speed, and the extracellular fraction increased from ≤ 10% to 20-90%. The effect of aeration on Fab localization was reproduced in multiwell plate by variation of culture volume. Conclusions Yield and leakage of Fab fragments are dependent on expression strain, culture medium, aeration rate, and the combination of these parameters. Maximum productivity in fed-batch-like conditions and in autoinduction medium is achieved under sufficiently oxygen-limited conditions, and lower aeration also promotes increased Fab accumulation into

  3. Handbook of solid waste disposal: materials and energy recovery

    Energy Technology Data Exchange (ETDEWEB)

    Pavoni, J L; Heer, Jr, J E; Hagerty, D J

    1975-01-01

    Traditional and innovative solid waste disposal techniques and new developments in materials and energy recovery systems are analyzed. Each method is evaluated in terms of system methodology, controlling process parameters, and process requirements, by-products, economics, and case histories. Medium and high temperature incineration; wet pulping; landfill with leachate recirculation; the Hercules, Inc., system; USBM front-end and back-end systems; pyrolysis; waste heat utilization, the Combustion Power Unit-400; use of refuse as a supplementary fuel; and methane production from anaerobic fermentation systems are considered, as well as sanitary landfilling, incineration, and composting. European solid waste management techniques are evaluated for their applicability to the US.

  4. Enhanced oil recovery by nanoparticles injection: Modeling and simulation

    KAUST Repository

    El-Amin, Mohamed; Sun, Shuyu; Salama, Amgad

    2013-01-01

    In the present paper, a mathematical model and numerical simulation to describe the nanoparticles-water suspension imbibes into a water-oil two-phase flow in a porous medium is introduced. We extend the model to include the negative capillary pressure and mixed relative permeabilities correlations to fit with the mixed-wet system. Also, buoyancy and capillary forces as well as Brownian diffusion are considered. Throughout this investigation, we monitor the changing of the fluids and solid properties due to addition of the nanoparticles and check for possible enhancement of the oil recovery process using numerical experiments.

  5. Evaluation of Insulin Medium or Chondrogenic Medium on Proliferation and Chondrogenesis of ATDC5 Cells

    OpenAIRE

    Yao, Yongchang; Zhai, Zhichen; Wang, Yingjun

    2014-01-01

    Background. The ATDC5 cell line is regarded as an excellent cell model for chondrogenesis. In most studies with ATDC5 cells, insulin medium (IM) was used to induce chondrogenesis while chondrogenic medium (CM), which was usually applied in chondrogenesis of mesenchymal stem cells (MSCs), was rarely used for ATDC5 cells. This study was mainly designed to investigate the effect of IM, CM, and growth medium (GM) on chondrogenesis of ATDC5 cells. Methods. ATDC5 cells were, respectively, cultured ...

  6. Loop transfer recovery for general observer architecture

    DEFF Research Database (Denmark)

    Niemann, Hans Henrik; Søgaard-Andersen, Per; Stoustrup, Jakob

    1991-01-01

    A general and concise formulation is given of the loop transfer recovery (LTR) design problem based on recovery errors. Three types of recovery errors are treated: open loop recovery, sensitivity recovery and input-output recovery errors. The three corresponding versions of the asymptotic recovery...... recovery cases. This general recovery formulation covers all known observer based compensator types as special cases. The conditions given in this setting are effectively the aim of all known LTR design methods. The recovery formulation is interpreted in terms of a modelmatching problem as well, which...... is examined by means of the Q-parametrization. It is shown how the general controller obtained by the Q-parametrization can be written as a Luenberger observer based controller. In all cases, n controller states suffice to achieve recovery. The compensators are characterized for errors both on the input...

  7. Performance of Hitchens-Pike-Todd-Hewitt medium for group B streptococcus screening in pregnant women.

    Directory of Open Access Journals (Sweden)

    Simone Cristina Castanho Sabaini de Melo

    Full Text Available Group B streptococcus (GBS, which commonly colonizes the female genital tract and rectum, can cause infections in newborns with varying severity, possibly leading to death. The aim of the present study was to evaluate Hitchens-Pike-Todd-Hewitt (HPTH medium performance for GBS screening in pregnant women. A descriptive analytical cross-sectional study was performed with 556 pregnant women, of which 496 were at 35-37 weeks of gestation and 60 were at ≥ 38 weeks of gestation. The study was conducted from September 2011 to March 2014 in northern Paraná, Brazil. Vaginal and anorectal clinical specimens from each pregnant woman were plated on sheep blood agar (SBA and seeded on HPTH medium and Todd-Hewitt enrichment broth. Of the 496 pregnant women at 35-37 weeks of gestation, 141 (28.4% were positive for GBS, based on the combination of the three culture media and clinical specimens. The GBS colonization rates that were detected by each medium were 22.2% for HPTH medium, 21.2% for SBA, and 13.1% for Todd-Hewitt enrichment broth. Of the 60 pregnant women at ≥ 38 weeks of gestation, seven (11.7% were positive for GBS. These results demonstrate that HPTH medium and SBA were more sensitive than Todd-Hewitt enrichment broth for GBS screening in pregnant women and good GBS recovery in culture, indicating that the two media should be used together for vaginal and anorectal specimens.

  8. 'That proves my point': How mediums reconstrue disconfirmation in medium-sitter interactions.

    Science.gov (United States)

    Enoksen, Anette Einan; Dickerson, Paul

    2018-04-01

    Previous research has examined how the talk of mediums attends to the epistemological status of their readings. Such work has identified that mediums frequently use question-framed propositions that are typically confirmed by the sitter, thereby conferring epistemological status on the medium. This study seeks to investigate what happens when the sitter disconfirms the propositions of the medium. The study focuses on the ways in which such disconfirmation can be responded to such that it is reconstrued as evidence of the psychic nature of the medium's reading. Televised demonstrations of psychic readings involving British and US mediums and their sitters are analysed. The results suggest that mediums rework disconfirmation as proof in several ways: first, by emphasizing the different access that sitter and medium have to knowledge (e.g., about the future); second, as evidence that the medium has access to the actual voice of the deceased (and may therefore mishear what the deceased has said to them); and third, as revealing an important truth that has hitherto been concealed from the sitter. The implications of these findings are considered for cases where speakers bring different and potentially competing, epistemological resources to an interaction. © 2018 The British Psychological Society.

  9. Citizenship and recovery: two intertwined concepts for civic-recovery.

    Science.gov (United States)

    Pelletier, Jean-François; Corbière, Marc; Lecomte, Tania; Briand, Catherine; Corrigan, Patrick; Davidson, Larry; Rowe, Michael

    2015-03-04

    Validation of the psychometric properties of a new measure of citizenship was required for a research project in the province of Quebec, Canada. This study was meant to study the interplay between recovery- and citizenship-oriented supportive employment. As recovery and citizenship were expected to be two related concepts, convergent validity between the Citizenship Measure (CM) and the Recovery Assessment Scale (RAS) was tested. Study objectives were to: 1) conduct exploratory factor analyses on the CM and confirmatory factor analysis on the RAS tools (construct validity), 2) calculate Cronbach's alphas for each dimension emerging from objective 1 (reliability), and 3) calculate correlations between all dimensions from both tools (convergent validity). Data were collected from 174 individuals with serious mental illness, working in social firms. Serious mental illnesses include major depression, schizophrenia, bipolar disorder, obsessive compulsive disorder, panic disorder, post traumatic stress disorder and borderline personality disorder. Five factors emerged from the exploratory factor analysis of the CM, with good reliability. Confirmatory factor analyses showed that the short and the long versions of the RAS present satisfactory results. Finally, the correlation matrix indicated that all dimensions from both tools are significantly correlated, thus confirming their convergent validity. This study confirms the validity and reliability of two tools, CM and RAS. These tools can be used in combination to assess citizenship and recovery, both of which may be combined in the new concept of civic-recovery.

  10. CHROMagar Orientation Medium Reduces Urine Culture Workload

    Science.gov (United States)

    Manickam, Kanchana; Karlowsky, James A.; Adam, Heather; Lagacé-Wiens, Philippe R. S.; Rendina, Assunta; Pang, Paulette; Murray, Brenda-Lee

    2013-01-01

    Microbiology laboratories continually strive to streamline and improve their urine culture algorithms because of the high volumes of urine specimens they receive and the modest numbers of those specimens that are ultimately considered clinically significant. In the current study, we quantitatively measured the impact of the introduction of CHROMagar Orientation (CO) medium into routine use in two hospital laboratories and compared it to conventional culture on blood and MacConkey agars. Based on data extracted from our Laboratory Information System from 2006 to 2011, the use of CO medium resulted in a 28% reduction in workload for additional procedures such as Gram stains, subcultures, identification panels, agglutination tests, and biochemical tests. The average number of workload units (one workload unit equals 1 min of hands-on labor) per urine specimen was significantly reduced (P < 0.0001; 95% confidence interval [CI], 0.5326 to 1.047) from 2.67 in 2006 (preimplementation of CO medium) to 1.88 in 2011 (postimplementation of CO medium). We conclude that the use of CO medium streamlined the urine culture process and increased bench throughput by reducing both workload and turnaround time in our laboratories. PMID:23363839

  11. Kansas Consortium Plug-in Hybrid Medium Duty

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2012-03-31

    On September 30, 2008, the US Department of Energy (DoE), issued a cooperative agreement award, DE-FC26-08NT01914, to the Metropolitan Energy Center (MEC), for a project known as “Kansas Consortium Plug-in Hybrid Medium Duty Certification” project. The cooperative agreement was awarded pursuant to H15915 in reference to H. R. 2764 Congressionally Directed Projects. The original agreement provided funding for The Consortium to implement the established project objectives as follows: (1) to understand the current state of the development of a test protocol for PHEV configurations; (2) to work with industry stakeholders to recommend a medium duty vehicle test protocol; (3) to utilize the Phase 1 Eaton PHEV F550 Chassis or other appropriate PHEV configurations to conduct emissions testing; (4) and to make an industry PHEV certification test protocol recommendation for medium duty trucks. Subsequent amendments to the initial agreement were made, the most significant being a revised Scope of Project Objectives (SOPO) that did not address actual field data since it was not available as originally expected. This project was mated by DOE with a parallel project award given to the South Coast Air Quality Management District (SCAQMD) in California. The SCAQMD project involved designing, building and testing of five medium duty plug-in hybrid electric trucks. SCAQMD had contracted with the Electric Power Research Institute (EPRI) to manage the project. EPRI provided the required match to the federal grant funds to both the SCAQMD project and the Kansas Consortium project. The rational for linking the two projects was that the data derived from the SCAQMD project could be used to validate the protocols developed by the Kansas Consortium team. At the same time, the consortium team would be a useful resource to SCAQMD in designating their test procedures for emissions and operating parameters and determining vehicle mileage. The years between award of the cooperative

  12. La narració gràfica en àmbit universitari. Perspectives didàctiques del còmic i de l’àlbum il·lustrat

    OpenAIRE

    Baile López, Eduard; Rovira-Collado, José; Maestre-Brotons, Antoni; Ortiz Hernández, Francisco Javier; Pomares Puig, María Pilar; Soler-Quílez, Guillermo; Villaverde Pérez, Abel; Sánchez Verdú, Ramón; Serna-Rodrigo, Rocío; Vidal Martín-Toledano, Jesús

    2017-01-01

    Mitjançant la xarxa 3858, s’ha pretés oferir, tal com ja s’ha fet en diverses convocatòries prèvies del programa de xarxes de la Universitat d’Alacant, presència acadèmica a la tasca d’estudi i de difusió sobre les possibilitats didàctiques del còmic que s’està desenvolupant des dels nuclis dels grups Unicòmic i CLUECA. En aquest sentit, la memòria aspira a ser testimoni del treball investigador i docent dut a terme pels membres de la xarxa durant el curs 2016-2017. Al nostre parer, fer recom...

  13. Veneno para la mente: La participación de los especialistas en salud mental en la campaña anti-cómic estadounidense (1940-1960)

    OpenAIRE

    Fernández Sarasola, Ignacio

    2016-01-01

    Entre 1940 y 1960 se desarrolló en Estados Unidos una intensa campaña anti-cómic impulsada por ciudadanos que consideraban que aquellas revistas no solo suponían una mala influencia para sus niños, sino que eran responsables de un incremento en la delincuencia juvenil. Un punto de inflexión se produjo en el momento en que psiquiatras y psicólogos se incorporaron a la citada campaña. Su líder fue Fredric Wertham, un psiquiatra de origen germano que acusó a los cómics de dañar la mente de los n...

  14. EL CÓMIC COMO RECURSO DIDÁCTICO PARA EL APRENDIZAJE DE LAS ACTIVIDADES FÍSICAS EN EL MEDIO NATURAL EN EL 2º CICLO DE LA EDUCACIÓN PRIMARIA ESPAÑOLA

    Directory of Open Access Journals (Sweden)

    Eliseo García Cantó

    2010-01-01

    Full Text Available El presente artículo pretende mostrar la manera de trabajar la competencia lingüística en el segundo ciclo del área de Educación Física en España y más concretamente en los contenidos relacionados con las actividades en la naturaleza, a través de una herramienta motivadora para los niños como es el cómic. El alumnado va a mejorar sus hábitos lectores a través de la lectura del cómic y la realización de su correspondiente ficha de trabajo.

  15. Hadrons in hot and dense medium

    International Nuclear Information System (INIS)

    Mallik, S.

    2004-01-01

    We review chiral perturbation theory in some detail and construct interaction terms involving the Goldstone and the different non-Goldstone fields, in presence of external (classical) fields coupled to currents. The ensemble average of the two-point functions of the currents can now be expanded in terms of Feynman diagrams. We evaluate the one-loop diagrams in the neighbourhood of the respective poles to find the effective couplings and masses of the particles in medium. We also describe the virial formula for the self-energy of a particle in medium, giving its pole position. It proves useful if the scattering amplitude of the particle with particles in medium is known experimentally. (author)

  16. Charmonium propagation through a dense medium

    Directory of Open Access Journals (Sweden)

    Kopeliovich B.Z.

    2015-01-01

    Full Text Available Attenuation of a colourless c̄c dipole propagating with a large momentum through a hot medium originates from two sources, Debye screening (melting, and inelastic collisions with surrounding scattering centres (absorption. The former never terminates completely production of a bound charmonium in heavy ion collisions, even at very high temperatures. The latter, is controlled my the magnitude of the dipole cross section, related to the transport coefficient, which is the rate of transverse momentum broadening in the medium. A novel procedure of Lorentz boosting of the Schrödinger equation is developed, which allows to calculate the charmonium survival probability employing the path-integral technique, incorporating both melting and absorption. A novel mechanism of charmonium regeneration in a dense medium is proposed.

  17. Coherent neutrino interactions in a dense medium

    International Nuclear Information System (INIS)

    Kiers, K.; Weiss, N.

    1997-01-01

    Motivated by the effect of matter on neutrino oscillations (the MSW effect) we study in more detail the propagation of neutrinos in a dense medium. The dispersion relation for massive neutrinos in a medium is known to have a minimum at nonzero momentum p∼G F ρ/√(2). We study in detail the origin and consequences of this dispersion relation for both Dirac and Majorana neutrinos both in a toy model with only neutral currents and a single neutrino flavor and in a realistic open-quotes standard modelclose quotes with two neutrino flavors. We find that for a range of neutrino momenta near the minimum of the dispersion relation, Dirac neutrinos are trapped by their coherent interactions with the medium. This effect does not lead to the trapping of Majorana neutrinos. copyright 1997 The American Physical Society

  18. Temperature distribution in a uniformly moving medium

    International Nuclear Information System (INIS)

    Mitchell, Joseph D; Petrov, Nikola P

    2009-01-01

    We apply several physical ideas to determine the steady temperature distribution in a medium moving with uniform velocity between two infinite parallel plates. We compute it in the coordinate frame moving with the medium by integration over the 'past' to account for the influence of an infinite set of instantaneous point sources of heat in past moments as seen by an observer moving with the medium. The boundary heat flux is simulated by appropriately distributed point heat sources on the inner side of an adiabatically insulating boundary. We make an extensive use of the Green functions with an emphasis on their physical meaning. The methodology used in this paper is of great pedagogical value as it offers an opportunity for students to see the connection between powerful mathematical techniques and their physical interpretation in an intuitively clear physical problem. We suggest several problems and a challenging project that can be easily incorporated in undergraduate or graduate courses

  19. Graphene wire medium: Homogenization and application

    DEFF Research Database (Denmark)

    Andryieuski, Andrei; Chigrin, Dmitry N.; Lavrinenko, Andrei

    2012-01-01

    In this contribution we analyze numerically the optical properties of the graphene wire medium, which unit cell consists of a stripe of graphene embedded into dielectric. We propose a simple method for retrieval of the isofrequency contour and effective permittivity tensor. As an example of the g......In this contribution we analyze numerically the optical properties of the graphene wire medium, which unit cell consists of a stripe of graphene embedded into dielectric. We propose a simple method for retrieval of the isofrequency contour and effective permittivity tensor. As an example...... of the graphene wire medium application we demonstrate a reconfigurable hyperlens for the terahertz subwavelength imaging capable of resolving two sources with separation λ0/5 in the far-field....

  20. Small and medium size nuclear reactors

    International Nuclear Information System (INIS)

    Al-Mugrabi, M.A.

    1996-01-01

    The purpose of this appendix is to provide up-to-date technical information relevant to the deployment of small and medium reactors (SMRs). It summarizes the status of SMRs and discusses areas of relevance to their utilization, including seawater desalination; and in particular their simplicity, their flexibility for a variety of applications and the use of passive safety features as fundamental to most of these designs. In response to important commercial developments, the energy range of small and medium reactors is now taken as being up to around 700 MW(e). Detailed information on SMR designs can be found in the IAEA report on The Design and Development Status of Small and Medium Reactor Systems 1995. 5 refs, 2 figs, 1 tab

  1. Comparison of a radiometric method (BACTEC) and conventional culture media for recovery of mycobacteria from smear-negative specimens

    International Nuclear Information System (INIS)

    Morgan, M.A.; Horstmeier, C.D.; DeYoung, D.R.; Roberts, G.D.

    1983-01-01

    The BACTEC system and three conventional media (Middlebrook 7H10, selective Middlebrook 7H11 [S7H11], and Lowenstein-Jensen [LJ] were compared for their mean recovery times and recovery rates of mycobacteria from acid-fast, smear-negative clinical specimens. Of the 71 smear-negative, culture-positive specimens recovered from 2,165 submitted smear-negative cultures, the BACTEC system detected 71.8%, compared with 88.7% for the conventional three-medium system. When media were individually compared, BACTEC medium (Middlebrook 7H12) was more successful in recovering mycobacteria (71.8%) than was LJ (62%), Middlebrook medium 7H10 (55.9%), or Middlebrook S7H11 medium (52.1%). Middlebrook 7H11 medium containing sodium selenate was also evaluated and did not increase the recovery rate or decrease the recovery time of mycobacterial species when compared with LJ, Middlebrook 7H10, S7H11, and 7H12 media. The mean detection time for the BACTEC system was less than that by conventional methods for the seven species of mycobacteria recovered. Detection times for Mycobacterium tuberculosis on the BACTEC system and conventional cultural systems were 13.7 and 26.3 days, respectively

  2. H2 molecules and the intercloud medium

    International Nuclear Information System (INIS)

    Hill, J.K.; Hollenbach, D.J.

    1976-01-01

    We discuss expected column of densities of H 2 in the intercloud medium and the possible use of molecules as indicators of intercloud physical conditions. We treat molecule formation by the H - process and on graphite grains and show that the Barlow-Silk hypothesis of a 1 eV semichemical hydrogen-graphite bond leads to a large enhancement of the intercloud molecule formation rate. Rotational excitation calculations are presented for both cloud and intercloud conditions which show, in agreement with Jura, that the presently observed optically thin H 2 absorption components are more likely to originate in cold clouds than in the intercloud medium

  3. Medium for Children’s Creativity

    DEFF Research Database (Denmark)

    Borum, Nanna; Kristensen, Kasper; Petersson, Eva

    2014-01-01

    This paper reports on an exploratory study that investigates 16 elementary school children’s interaction with two different mediums for creativity, LEGO® bricks and paper collages, drawing on the previous creativity assessment test carried out by Amabile [1]. The study is based in a playful...... on labor when working with LEGO bricks. It was also evident that the children assigned preconceived affordances to the two mediums. The results from this study should feed into to a technology enhanced playful learning environment and these are the initial steps in the design process....

  4. Heavy quark energy loss in nuclear medium

    International Nuclear Information System (INIS)

    Zhang, Benr-Wei; Wang, Enke; Wang, Xin-Nian

    2003-01-01

    Multiple scattering, modified fragmentation functions and radiative energy loss of a heavy quark propagating in a nuclear medium are investigated in perturbative QCD. Because of the quark mass dependence of the gluon formation time, the medium size dependence of heavy quark energy loss is found to change from a linear to a quadratic form when the initial energy and momentum scale are increased relative to the quark mass. The radiative energy loss is also significantly suppressed relative to a light quark due to the suppression of collinear gluon emission by a heavy quark

  5. Power converters for medium voltage networks

    CERN Document Server

    Islam, Md Rabiul; Zhu, Jianguo

    2014-01-01

    This book examines a number of topics, mainly in connection with advances in semiconductor devices and magnetic materials and developments in medium and large-scale renewable power plant technologies, grid integration techniques and new converter topologies, including advanced digital control systems for medium-voltage networks. The book's individual chapters provide an extensive compilation of fundamental theories and in-depth information on current research and development trends, while also exploring new approaches to overcoming some critical limitations of conventional grid integration te

  6. Structure and evolution of the interstellar medium

    International Nuclear Information System (INIS)

    Chieze, J.P.

    1985-10-01

    We give a two dimensional hydrodynamical analysis of HI clouds collisions in order to determine the mass spectrum of diffuse interstellar clouds. We have taken into account evaporation and abrasion by supernovae blast waves. The conditions for cloud merging or fragmentation are precised. Applications to the model of the interstellar medium of Mc Kee and Ostriker are also discussed. On the other hand, we show that molecular clouds belong to a one parameter family which can be identified to the sequence of the gravitationally unstable states of clouds bounded by the uniform pressure of the coronal phase of the interstellar medium. Hierarchical fragmentation of molecular clouds is analysed in this context [fr

  7. Valor de las pruebas inmunológicas en el diagnóstico de las enfermedades micóticas: experiencia de un centro de referencia

    Directory of Open Access Journals (Sweden)

    Magaly Chinchilla

    1998-09-01

    Full Text Available Las pruebas inmunológicas han sido ampliamente utilizadas como evidencia indirecta de infección micótica y tienen valor diagnóstico; algunas de estas pruebas pueden ser fácilmente adaptadas en los laboratorios con un bajo nivel de complejidad. El Laboratorio de Mitología del Grupo de Microbiología del lnstituto Nacional de Salud es centro de referencia para el diagnóstico de las micosis sistémicas en el país; por tal motivo y con el fin de establecer una red nacional, se seleccionaron cuatro laboratorios regionales y se entrenó personal en técnicas inmunológicas para realizar el diagnóstico de la histoplasmosis y de la paracoccidioidomicosis. Las técnicas empleadas fueron: inmunodifusión (ID para histoplasmosis, paracoccidioidomicosis y aspergilosis; fijación de complemento (FC para histoplasmosis y paracoccidioidomicosis y, aglutinación con partículas de látex para la antigenemia en la criptococosis. En un período de 7 años (1990 -1996, los laboratorios procesaron 6.841 muestras de suero correspondientes a 6.411 pacientes con diagnósticos compatibles con micosis sistémicas. Los cuatro laboratorios regionales analizaron 1.918 muestras (28% y el centro de referencia, 4.923 (72%. La reactividad total fue de 13,5% (923/6.841, discriminada así: histoplasmosis, 42,5%; paracoccidioidomicosis, 33%; criptococosis, 21,2%, y aspergilosis, 3,3%. El número total de casos diagnosticados fue de 441: 155 histoplasmosis, 120 paracoccidioidomicosis, 138 criptococosis y 28 aspergilosis. El empleo de la ID en los centros regionales permitió el diagnóstico de 31% de los pacientes con histoplasmosis, de 41,6% de los pacientes con paracoccidioidomicosis y 53,6% de los pacientes con aspergilosis, lo cual indica que el diagnóstico precoz se puede realizar a nivel regional. La sensibilidad y la simplicidad de la prueba de ID constituye un excelente recurso para los laboratorios de baja complejidad, a nivel regional, que operan en áreas endémicas.

  8. Fuel retention and recovery in natural and MGI disruptions on KSTAR

    International Nuclear Information System (INIS)

    Yu, Y.W.; Hong, S.H.; Yoon, S.W.; Kim, K.P.; Kim, W.C.; Seo, D.C.

    2013-01-01

    Fuel retention and recovery are studied during natural and Massive Gas Injection (MGI) induced disruptions in KSTAR with full graphite wall. The amount of released particles in natural disruptions in 15 s after the discharge is ∼5–10 times higher than that of non-disruption shots, but the difference is only ∼ 2 MGI induced disruptions depends on magnetic field (B t ) and MGI amount. The MGI disruption under a low B t and a medium MGI amount shows shorter thermal quench (TQ) and current quench (CQ), thereby higher fuel recovery. High B t plasma requires higher MGI amount for both disruption mitigation and fuel recovery. A high recovery of 4.2 × 10 22 D (∼0.78 monolayers) is obtained by MGI disruption in KSTAR 2011

  9. Mechanical recovery of oil in ice

    International Nuclear Information System (INIS)

    Solsberg, L.B.; McGrath, M.

    1992-01-01

    A literature review was performed on the mechanical systems used for removing oil in ice. The most promising spill cleanup techniques were identified along with recommendations for future work. Catalogued data in the review focused on skimmers, of which rope mop machines were considered as having the most versatile approach. The performance of the Foxtail VAB 8-14 skimmer was then assessed in North Slope crude oil and diesel fuel at a test site in Alaska. The skimmer operates through a remote power pack and pump, and incorporates eight vertically oriented rope mops. It weighs 900 kg and is suspended from a crane when deployed. Three independent test parameters were measured: oil type, slick thickness, and ice cover. A test strategy was devised to isolate the effects of individual parameters on skimming in order to optimize machine performance. Skimmer performance was based on the percent oil in the recovered oil/water mixture and the net oil collection rate. Skimmer performance was found to be optimal at rope mop speeds of 0.2-0.3 m/s in medium range viscosity oils. The unit tested was significantly less effective in diesel. Overall, the Foxtail skimmer was found to comprise an oil recovery concept that has excellent potential and affords versatility for many oil-in-ice applications. 4 figs., 1 tab

  10. Actinide recovery from pyrochemical residues

    International Nuclear Information System (INIS)

    Avens, L.R.; Clifton, D.G.; Vigil, A.R.

    1984-01-01

    A new process for recovery of plutonium and americium from pyrochemical waste has been demonstrated. It is based on chloride solution anion exchange at low acidity, which eliminates corrosive HCl fumes. Developmental experiments of the process flowsheet concentrated on molten salt extraction (MSE) residues and gave >95% plutonium and >90% americium recovery. The recovered plutonium contained 6 = from high chloride-low acid solution. Americium and other metals are washed from the ion exchange column with 1N HNO 3 -4.8M NaCl. The plutonium is recovered, after elution, via hydroxide precipitation, while the americium is recovered via NaHCO 3 precipitation. All filtrates from the process are discardable as low-level contaminated waste. Production-scale experiments are now in progress for MSE residues. Flow sheets for actinide recovery from electrorefining and direct oxide reduction residues are presented and discussed

  11. Device for controlling gas recovery

    International Nuclear Information System (INIS)

    Ichioka, Atsushi.

    1976-01-01

    Purpose: To provide a controlling device for UF 6 gas recovery device, which can increase working efficiency and to discriminate normality and abnormality of the recovery device. Constitution: The gas recovery device comprises a plurality of traps, which are connected in series. The UF 6 gas is introduced into the first trap where adsorbing work is taken place to accumulate UF 6 gases, and the UF 6 gases partly flow into the succeeding trap. Even in this trap, when the adsorbing work begins, the succeeding trap is operated in series fashion. In this manner, two traps are continuously operated to recover the gases while performing the steps of adsorbing, waiting and regenerating in that order. The switching operation of the aforesaid steps is accomplished on the basis of concentration of the UF 6 detected between two traps, which are continuously driven. (Kamimura, M.)

  12. Uranium recovery from AVLIS slag

    International Nuclear Information System (INIS)

    D'Agostino, A.E.; Mycroft, J.R.; Oliver, A.J.; Schneider, P.G.; Richardson, K.L.

    2000-01-01

    Uranium metal for the Atomic Vapor Laser Isotope Separation (AVLIS) project was to have been produced by the magnesiothermic reduction of uranium tetrafluoride. The other product from this reaction is a magnesium fluoride slag, which contains fine and entrained natural uranium as metal and oxide. Recovery of the uranium through conventional mill leaching would not give a magnesium residue free of uranium but to achieve more complete uranium recovery requires the destruction of the magnesium fluoride matrix and liberation of the entrapped uranium. Alternate methods of carrying out such treatments and the potential for recovery of other valuable byproducts were examined. Based on the process flowsheets, a number of economic assessments were performed, conclusions were drawn and the preferred processing alternatives were identified. (author)

  13. Fluid diversion in oil recovery

    International Nuclear Information System (INIS)

    Nimir, Hassan B.

    1999-01-01

    In any oil recovery process, large scale heterogeneities, such as fractures, channels, or high-permeability streaks, can cause early break through of injected fluid which will reduce oil recovery efficiency. In waterflooding, enhanced oil recovery, and acidizing operations, this problem is particularly acute because of the cost of the injected fluid. On the other hand coping with excess water production is always a challenging task for field operators. The cost of handling and disposing produced water can significantly shorten the economic production life of an oil well. The hydrostatic pressure created by high fluid levels in a well (water coning) is also detrimental to oil production. In this paper, the concept of fluid diversion is explained. Different methods that are suggested to divert the fluid into the oil-bearing-zones are briefly discussed, to show their advantages and disadvantages. Methods of reducing water production in production well are also discussed. (Author)

  14. Recovery efficiencies for Burkholderia thailandensis from various aerosol sampling media

    Directory of Open Access Journals (Sweden)

    Paul eDabisch

    2012-06-01

    Full Text Available Burkholderia thailandensis is used in the laboratory as a surrogate of the more virulent B. pseudomallei. Since inhalation is believed to be a natural route of infection for B. pseudomallei, many animal studies with B. pseudomallei and B. thailandensis utilize the inhalation route of exposure. The aim of the present study was to quantify the recovery efficiency of culturable B. thailandensis from several common aerosol sampling devices to ensure that collected microorganisms could be reliably recovered post-collection. The sampling devices tested included 25-mm gelatin filters, 25-mm stainless steel disks used in Mercer cascade impactors, and two types of glass impingers. The results demonstrate that while several processing methods tested resulted in significantly lower physical recovery efficiencies than other methods, it was possible to obtain culturable recovery efficiencies for B. thailandensis and physical recovery efficiencies for 1 μm fluorescent spheres of at least 0.95 from all of the sampling media tested given an appropriate sample processing procedure. The results of the present study also demonstrated that the bubbling action of liquid media in all-glass impingers (AGIs can result in physical loss of material from the collection medium, although additional studies are needed to verify the exact mechanisms involved. Overall, the results of this study demonstrate that the collection mechanism as well as the post-collection processing method can significantly affect the recovery from and retention of culturable microorganisms in sampling media, potentially affecting the calculated airborne concentration and any subsequent estimations of risk or dose derived from such data.

  15. Optimizing culture medium for debittering constitutive enzyme ...

    African Journals Online (AJOL)

    STORAGESEVER

    2010-08-02

    Aug 2, 2010 ... naringinase on different matrices has been studied by many researchers (Busto et ... 10 g/L in the base medium compared to naringin control. Nitrogen ... Fermentation experiments were carried out in shaking flask for 5 days at 28°C with initial pH 6.0. † Values ..... fujikuroi mycelium in fluidized bioreactors.

  16. Jet multiplicity distributions: medium dependence in MLLA

    Energy Technology Data Exchange (ETDEWEB)

    Armesto, Nestor; Pajares, Carlos; Quiroga-Arias, Paloma [Universidade de Santiago de Compostela, Departamento de Fisica de Particulas and IGFAE, Santiago de Compostela (Spain)

    2009-07-15

    We study the medium dependence of the multiplicity distributions in the modified leading logarithmic approximation. We focus in the enhancement in the number of branchings as the partons travel trough a dense medium created in a heavy-ion collision. We study the effect of a higher number of splittings in some jet observables by introducing the medium as a constant (f{sub med}) in the splitting functions. Having as our ansatz for the quark and gluon jets mean multiplicities left angle n{sub G} right angle =e{sup {gamma}}{sup y} and left angle n{sub Q} right angle =r{sup -1}e{sup {gamma}}{sup y}, we study in an analytic approach the dependence with the medium (f{sub med}) of the anomalous dimension ({gamma}), the multiplicity ratio (r), and so the mean multiplicities. We also obtain the higher-order moments of the multiplicity distribution, what allows us to study its dispersion. (orig.)

  17. Wave propagation in thermoelastic saturated porous medium

    Indian Academy of Sciences (India)

    the existence and propagation of four waves in the medium. Three of the waves are ... predicted infinite speed for propagation of ther- mal signals. Lord and ..... saturated reservoir rock (North-sea Sandstone) is chosen for the numerical model ...

  18. Innovation in Small and Medium Firms.

    Science.gov (United States)

    Organisation for Economic Cooperation and Development, Paris (France). Committee for Scientific and Technical Personnel.

    A study analyzed the policies of 20 Organisation for Economic Cooperation and Development (OECD) member countries pertaining to small and medium enterprises (SMEs). Aims of the study were to assess the current role of SMEs as generators and users of innovations, to analyze the components of a favorable climate for innovation in SMEs, and to…

  19. The MIRI Medium Resolution Spectrometer calibration pipeline

    NARCIS (Netherlands)

    Labiano, A.; Azzollini, R.; Bailey, J.; Beard, S.; Dicken, D.; García-Marín, M.; Geers, V.; Glasse, A.; Glauser, A.; Gordon, K.; Justtanont, K.; Klaassen, P.; Lahuis, F.; Law, D.; Morrison, J.; Müller, M.; Rieke, G.; Vandenbussche, B.; Wright, G.

    2016-01-01

    The Mid-Infrared Instrument (MIRI) Medium Resolution Spectrometer (MRS) is the only mid-IR Integral Field Spectrometer on board James Webb Space Telescope. The complexity of the MRS requires a very specialized pipeline, with some specific steps not present in other pipelines of JWST instruments,

  20. Separation medium containing thermally exfoliated graphite oxide

    Science.gov (United States)

    Prud'homme, Robert K. (Inventor); Aksay, Ilhan A. (Inventor); Herrera-Alonso, Margarita (Inventor)

    2012-01-01

    A separation medium, such as a chromatography filling or packing, containing a modified graphite oxide material, which is a thermally exfoliated graphite oxide with a surface area of from about 300 m.sup.2/g to 2600 m.sup.2/g, wherein the thermally exfoliated graphite oxide has a surface that has been at least partially functionalized.