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Sample records for mfg div personal

  1. The DivJ, CbrA and PleC system controls DivK phosphorylation and symbiosis in Sinorhizobium meliloti

    Science.gov (United States)

    Pini, Francesco; Frage, Benjamin; Ferri, Lorenzo; De Nisco, Nicole J.; Mohapatra, Saswat S.; Taddei, Lucilla; Fioravanti, Antonella; Dewitte, Frederique; Galardini, Marco; Brilli, Matteo; Villeret, Vincent; Bazzicalupo, Marco; Mengoni, Alessio; Walker, Graham C.; Becker, Anke; Biondi, Emanuele G.

    2013-01-01

    SUMMARY Sinorhizobium meliloti is a soil bacterium that invades the root nodules it induces on Medicago sativa, whereupon it undergoes an alteration of its cell cycle and differentiates into nitrogen-fixing, elongated and polyploid bacteroid with higher membrane permeability. In Caulobacter crescentus, a related alphaproteobacterium, the principal cell cycle regulator, CtrA, is inhibited by the phosphorylated response regulator DivK. The phosphorylation of DivK depends on the histidine kinase DivJ, while PleC is the principal phosphatase for DivK. Despite the importance of the DivJ in C. crescentus, the mechanistic role of this kinase has never been elucidated in other Alphaproteobacteria. We show here that the histidine kinases DivJ together with CbrA and PleC participate in a complex phosphorylation system of the essential response regulator DivK in S. meliloti. In particular, DivJ and CbrA are involved in DivK phosphorylation and in turn CtrA inactivation, thereby controlling correct cell cycle progression and the integrity of the cell envelope. In contrast, the essential PleC presumably acts as a phosphatase of DivK. Interestingly, we found that a DivJ mutant is able to elicit nodules and enter plant cells, but fails to establish an effective symbiosis suggesting that proper envelope and/or low CtrA levels are required for symbiosis. PMID:23909720

  2. Correlation between MFG-E8 and MIRI in elderly patients

    Directory of Open Access Journals (Sweden)

    Bing Jiang

    2016-09-01

    Full Text Available Objective: To explore the correlation between MFG-E8 and CHD in elderly patients with MIRI, and to provide help for CHD patients with ischemic reperfusion therapy in the future. Methods: A total of 94 CHD patients in our hospital were selected as the observation group and treated with reperfusion operation. The patients with chest discomfort and no significant stenosis of coronary artery were selected as control group; Before and after operation, the changes of MFG-E8 and the downstream factor MCP-1, TGF-毬1, inflammatory factors hsCRP, IL-6 and ICAM-1 in each group were detected in 24 h and 48 h after operation, and the correlation between MFG-E8 with various indexes and MIRI was analyzed. Results: MFGE8 at each time point of the observation group were significantly lower than that of the control group (P0.05; the level of inflammatory factors hs-CRP, IL-6, ICAM-1 at each time points of the observation group were significantly higher than that of the control group (P<0.05; the levels of inflammatory factors were significantly higher than those preoperative (P<0.05, the level of hs-CRP at 48 h was significantly lower than that at 24 h, IL-6 and ICAM-1 were increased over time; the level of inflammatory factors were negatively correlated with MFG-E8. In the observation group, the serum TNF-毬, MCP-1 and at different time points were significantly higher than those in the control group (P<0.05; TNF-毬 and MCP-1 were significantly higher than that before operation, and the TNF-毬 and MCP-1 in 48 h were significantly higher than those in 24 h (P<0.05; TNF-毬 and MCP-1 were positively correlated with MFG-E8. Conclusions: Inflammation plays a key role in elderly patients with MIRI. MFG-E8 acts as a defense against inflammation, and can help in reducing MIRI, which provids help for the future treatment of myocardial ischemia reperfusion.

  3. Effect of varying temperature on growth, morphology and soluble protein content of div I and div II mutant strains of bacillus sub tills

    International Nuclear Information System (INIS)

    Ahmed, A.; Sabri, A.N.

    2004-01-01

    In B.subtilis, cell division is controlled by div-genes which have been mapped on its circular chromosome. In the present work, div-mutant strains 1A316(div II), 1A317 and 1A318 (div I) were studied. These strains exhibited temperature sensitive cell division mutations. Colony morphology, cell morphology, staining behavior, growth rate and protein content of PY79 (wild type) and div-mutant strains (1A316, 1A317, 1A318) was studied at different temperatures ( 25 deg. Centi grade and 42 deg. with varying incubation periods(4, 16, 24, 48, 72,96 hrs). div-mutants differ from wild type (PY79) in colony morphology. Colony margin in PY79 was entire while in the div strains it is undulate. Staining behavior of cells as well as cell morphology i.e., cell size, cell types, formation of filaments/minicells were affected by high temperature. At higher temperature (42 deg. Centi grade), div-mutants undergo more severe lysis and degeneration as compare to wild type (PY79). Defective spores were produced by div-mutants at 25 deg. Centi grade and 42 deg. Centi grade. Tetrazolium overlay test was performed at 37 deg. Centi grade and 42 deg. Centi grade to check the spore germination ability of wild type and div-mutants. In 1A318, defective spores were produced at 37 deg. Centi grade, div-mutant was checked after 24 and 96 hrs at different temperatures (25, 37 and 42 deg. Centi grade). At all temperatures protein content were more in PY79 as compare to div-mutants. Also at 25 and 42 deg. Centi grade, protein content was more as compare to 37 deg. Centi grade. Protein contents was reduced at sporulation stages. Thus cell division mutations affect cell morphology, sporulation and germination processes in B.subtilis and thus are multifaceted mutations. (author)

  4. A minimalist functional group (MFG) approach for surrogate fuel formulation

    KAUST Repository

    Abdul Jameel, Abdul Gani

    2018-03-20

    Surrogate fuel formulation has drawn significant interest due to its relevance towards understanding combustion properties of complex fuel mixtures. In this work, we present a novel approach for surrogate fuel formulation by matching target fuel functional groups, while minimizing the number of surrogate species. Five key functional groups; paraffinic CH, paraffinic CH, paraffinic CH, naphthenic CH–CH and aromatic C–CH groups in addition to structural information provided by the Branching Index (BI) were chosen as matching targets. Surrogates were developed for six FACE (Fuels for Advanced Combustion Engines) gasoline target fuels, namely FACE A, C, F, G, I and J. The five functional groups present in the fuels were qualitatively and quantitatively identified using high resolution H Nuclear Magnetic Resonance (NMR) spectroscopy. A further constraint was imposed in limiting the number of surrogate components to a maximum of two. This simplifies the process of surrogate formulation, facilitates surrogate testing, and significantly reduces the size and time involved in developing chemical kinetic models by reducing the number of thermochemical and kinetic parameters requiring estimation. Fewer species also reduces the computational expenses involved in simulating combustion in practical devices. The proposed surrogate formulation methodology is denoted as the Minimalist Functional Group (MFG) approach. The MFG surrogates were experimentally tested against their target fuels using Ignition Delay Times (IDT) measured in an Ignition Quality Tester (IQT), as specified by the standard ASTM D6890 methodology, and in a Rapid Compression Machine (RCM). Threshold Sooting Index (TSI) and Smoke Point (SP) measurements were also performed to determine the sooting propensities of the surrogates and target fuels. The results showed that MFG surrogates were able to reproduce the aforementioned combustion properties of the target FACE gasolines across a wide range of conditions

  5. A minimalist functional group (MFG) approach for surrogate fuel formulation

    KAUST Repository

    Abdul Jameel, Abdul Gani; Naser, Nimal; Issayev, Gani; Touitou, Jamal; Ghosh, Manik Kumer; Emwas, Abdul-Hamid M.; Farooq, Aamir; Dooley, Stephen; Sarathy, Mani

    2018-01-01

    Surrogate fuel formulation has drawn significant interest due to its relevance towards understanding combustion properties of complex fuel mixtures. In this work, we present a novel approach for surrogate fuel formulation by matching target fuel functional groups, while minimizing the number of surrogate species. Five key functional groups; paraffinic CH, paraffinic CH, paraffinic CH, naphthenic CH–CH and aromatic C–CH groups in addition to structural information provided by the Branching Index (BI) were chosen as matching targets. Surrogates were developed for six FACE (Fuels for Advanced Combustion Engines) gasoline target fuels, namely FACE A, C, F, G, I and J. The five functional groups present in the fuels were qualitatively and quantitatively identified using high resolution H Nuclear Magnetic Resonance (NMR) spectroscopy. A further constraint was imposed in limiting the number of surrogate components to a maximum of two. This simplifies the process of surrogate formulation, facilitates surrogate testing, and significantly reduces the size and time involved in developing chemical kinetic models by reducing the number of thermochemical and kinetic parameters requiring estimation. Fewer species also reduces the computational expenses involved in simulating combustion in practical devices. The proposed surrogate formulation methodology is denoted as the Minimalist Functional Group (MFG) approach. The MFG surrogates were experimentally tested against their target fuels using Ignition Delay Times (IDT) measured in an Ignition Quality Tester (IQT), as specified by the standard ASTM D6890 methodology, and in a Rapid Compression Machine (RCM). Threshold Sooting Index (TSI) and Smoke Point (SP) measurements were also performed to determine the sooting propensities of the surrogates and target fuels. The results showed that MFG surrogates were able to reproduce the aforementioned combustion properties of the target FACE gasolines across a wide range of conditions

  6. Phyto-gegographycal analysis of Divčibare

    Directory of Open Access Journals (Sweden)

    Popović Ivana

    2005-01-01

    Full Text Available The aim of phytogeographical analysis is to determine the plant species origin, genesis and migrations. The study results contribute to the knowledge of phytogeographical classification of the particular regions. Different chorions, by their effects, determine the flora structure and composition. The aim of the floristic research of Divčibare was to identify the diversity of flora in this region, i.e., in a wider sense, the diversity of flora in Serbia. Phytogeographical analysis was based on floristic research. The identified plant species were classified into the corresponding floral elements, area groups and area types. The data on diversity and the degree of representation in the flora of Divčibare were obtained based on the percentage of each area type. It was concluded that the flora of Divčibare has a transitional, Central European-Mediterranean-Pontic character.

  7. MFG-E8 Reprogramming of Macrophages Promotes Wound Healing by Increased bFGF Production and Fibroblast Functions.

    Science.gov (United States)

    Laplante, Patrick; Brillant-Marquis, Frédéric; Brissette, Marie-Joëlle; Joannette-Pilon, Benjamin; Cayrol, Romain; Kokta, Victor; Cailhier, Jean-François

    2017-09-01

    Macrophages are essential for tissue repair. They have a crucial role in cutaneous wound healing, participating actively in the inflammation phase of the process. Unregulated macrophage activation may, however, represent a source of excessive inflammation, leading to abnormal wound healing and hypertrophic scars. Our research group has shown that apoptotic endothelial and epithelial cells secrete MFG-E8, which has the ability to reprogram macrophages from an M1 (proinflammatory) to an M2 (anti-inflammatory, pro-repair) phenotype. Hence, we tested whether modulation of macrophage reprogramming would promote tissue repair. Using a mouse model of wound healing, we showed that the presence and/or addition of MFG-E8 favors wound closure associated with an increase in CD206-positive cells and basic fibroblast growth factor production in healing tissues. More importantly, adoptive transfer of ex vivo MFG-E8-treated macrophages promoted wound closure. We also observed that MFG-E8-treated macrophages produced basic fibroblast growth factor that is responsible for fibroblast migration and proliferation. Taken together, our results strongly suggest that MFG-E8 plays a key role in macrophage reprogramming in tissue healing through induction of an anti-inflammatory M2 phenotype and basic fibroblast growth factor production, leading to fibroblast migration and wound closure. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

  8. Regulation of Na+ channel inactivation by the DIII and DIV voltage-sensing domains.

    Science.gov (United States)

    Hsu, Eric J; Zhu, Wandi; Schubert, Angela R; Voelker, Taylor; Varga, Zoltan; Silva, Jonathan R

    2017-03-06

    Functional eukaryotic voltage-gated Na + (Na V ) channels comprise four domains (DI-DIV), each containing six membrane-spanning segments (S1-S6). Voltage sensing is accomplished by the first four membrane-spanning segments (S1-S4), which together form a voltage-sensing domain (VSD). A critical Na V channel gating process, inactivation, has previously been linked to activation of the VSDs in DIII and DIV. Here, we probe this interaction by using voltage-clamp fluorometry to observe VSD kinetics in the presence of mutations at locations that have been shown to impair Na V channel inactivation. These locations include the DIII-DIV linker, the DIII S4-S5 linker, and the DIV S4-S5 linker. Our results show that, within the 10-ms timeframe of fast inactivation, the DIV-VSD is the primary regulator of inactivation. However, after longer 100-ms pulses, the DIII-DIV linker slows DIII-VSD deactivation, and the rate of DIII deactivation correlates strongly with the rate of recovery from inactivation. Our results imply that, over the course of an action potential, DIV-VSDs regulate the onset of fast inactivation while DIII-VSDs determine its recovery. © 2017 Hsu et al.

  9. SecA is required for membrane targeting of the cell division protein DivIVA in vivo

    Directory of Open Access Journals (Sweden)

    Sven eHalbedel

    2014-02-01

    Full Text Available The conserved protein DivIVA is involved in different morphogenetic processes in Gram-positive bacteria. In Bacillus subtilis, the protein localises to the cell division site and cell poles, and functions as a scaffold for proteins that regulate division site selection, and for proteins that are required for sporulation. To identify other proteins that bind to DivIVA, we performed an in vivo cross-linking experiment. A possible candidate that emerged was the secretion motor ATPase SecA. SecA mutants have been described that inhibit sporulation, and since DivIVA is necessary for sporulation, we examined the localisation of DivIVA in these mutants. Surprisingly, DivIVA was delocalised, suggesting that SecA is required for DivIVA targeting. To further corroborate this, we performed SecA depletion and inhibition experiments, which provided further indications that DivIVA localisation depends on SecA. Cell fractionation experiments showed that SecA is important for binding of DivIVA to the cell membrane. This was unexpected since DivIVA does not contain a signal sequence, and is able to bind to artificial lipid membranes in vitro without support of other proteins. SecA is required for protein secretion and membrane insertion, and therefore its role in DivIVA localisation is likely indirect. Possible alternative roles of SecA in DivIVA folding and/or targeting are discussed.

  10. Parallel Auxiliary Space AMG Solver for $H(div)$ Problems

    Energy Technology Data Exchange (ETDEWEB)

    Kolev, Tzanio V. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Vassilevski, Panayot S. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2012-12-18

    We present a family of scalable preconditioners for matrices arising in the discretization of $H(div)$ problems using the lowest order Raviart--Thomas finite elements. Our approach belongs to the class of “auxiliary space''--based methods and requires only the finite element stiffness matrix plus some minimal additional discretization information about the topology and orientation of mesh entities. Also, we provide a detailed algebraic description of the theory, parallel implementation, and different variants of this parallel auxiliary space divergence solver (ADS) and discuss its relations to the Hiptmair--Xu (HX) auxiliary space decomposition of $H(div)$ [SIAM J. Numer. Anal., 45 (2007), pp. 2483--2509] and to the auxiliary space Maxwell solver AMS [J. Comput. Math., 27 (2009), pp. 604--623]. Finally, an extensive set of numerical experiments demonstrates the robustness and scalability of our implementation on large-scale $H(div)$ problems with large jumps in the material coefficients.

  11. Parallel Solver for H(div) Problems Using Hybridization and AMG

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Chak S. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Vassilevski, Panayot S. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2016-01-15

    In this paper, a scalable parallel solver is proposed for H(div) problems discretized by arbitrary order finite elements on general unstructured meshes. The solver is based on hybridization and algebraic multigrid (AMG). Unlike some previously studied H(div) solvers, the hybridization solver does not require discrete curl and gradient operators as additional input from the user. Instead, only some element information is needed in the construction of the solver. The hybridization results in a H1-equivalent symmetric positive definite system, which is then rescaled and solved by AMG solvers designed for H1 problems. Weak and strong scaling of the method are examined through several numerical tests. Our numerical results show that the proposed solver provides a promising alternative to ADS, a state-of-the-art solver [12], for H(div) problems. In fact, it outperforms ADS for higher order elements.

  12. 75 FR 49526 - Halliburton Company, Duncan Mfg., Including On-Site Leased Workers from Express Personnel...

    Science.gov (United States)

    2010-08-13

    ... Company, Duncan Mfg., Including On-Site Leased Workers from Express Personnel, Clayton Personnel Service, and Manpower Planning, Duncan, OK; Halliburton Company, Technology and Engineering Division, Finance... Halliburton Company, Technology and Engineering Division, and Finance and Administration Division, Duncan...

  13. Register of Planned Emergency Producers.

    Science.gov (United States)

    1991-04-01

    879 1 HELVOET PHARMA INC. PENNSAUKEN NJ 461096 $80 1 FASLOK MILLS INC MURRAT HILL NJ 439625 619 1 HERCULES INC 3 FASRITE LAMINATING CORP WOOD RIDGE...317252 628 HARRIS CORPORATION 1 GENERAL ELECTRIC COMPANY 3 PRO ELECTRONICS DIV WESTBURY NT A 799145 678 CHEMICA . & MEDICAL DIV HASSALL JOHN INC...ELECTRONim CS Ca, IMC V SAYVILLE Ut A 56730 1 sit PARAMaOUNT nACacmnil cO INC DER PARK my 113336 ITS L&UNAMM MFG CORP ROliKONKOMA MY A 58047S I PTO# INC1

  14. Back to the Future: Personality and Assessment and Personality Development

    OpenAIRE

    Roberts, Brent W.

    2009-01-01

    In this essay I consider the future of personality development in light of the past effects of Personality and Assessment on the field of personality in general and personality development in particular. The essay is organized around 1) the effect of Mischel's book on the foundational theories informing personality development; 2) definitions of personality traits; 3) an alternative model of personality traits, described as the sociogenomic model of personality traits, that can bridge the div...

  15. Asymmetric division and differential gene expression during a bacterial developmental program requires DivIVA.

    Directory of Open Access Journals (Sweden)

    Prahathees Eswaramoorthy

    2014-08-01

    Full Text Available Sporulation in the bacterium Bacillus subtilis is a developmental program in which a progenitor cell differentiates into two different cell types, the smaller of which eventually becomes a dormant cell called a spore. The process begins with an asymmetric cell division event, followed by the activation of a transcription factor, σF, specifically in the smaller cell. Here, we show that the structural protein DivIVA localizes to the polar septum during sporulation and is required for asymmetric division and the compartment-specific activation of σF. Both events are known to require a protein called SpoIIE, which also localizes to the polar septum. We show that DivIVA copurifies with SpoIIE and that DivIVA may anchor SpoIIE briefly to the assembling polar septum before SpoIIE is subsequently released into the forespore membrane and recaptured at the polar septum. Finally, using super-resolution microscopy, we demonstrate that DivIVA and SpoIIE ultimately display a biased localization on the side of the polar septum that faces the smaller compartment in which σF is activated.

  16. 76 FR 22672 - Grant of Authority for Subzone Status, Allegro Mfg. Inc. (Distribution of Cosmetic, Organizer and...

    Science.gov (United States)

    2011-04-22

    ... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [Order No. 1754] Grant of Authority for Subzone Status, Allegro Mfg. Inc. (Distribution of Cosmetic, Organizer and Electronic Bags and Accessories... grants authority for subzone status for activity related to cosmetic, organizer and electronic bags and...

  17. Spectral mimetic least-squares method for div-curl systems

    NARCIS (Netherlands)

    Gerritsma, Marc; Palha, Artur; Lirkov, I.; Margenov, S.

    2018-01-01

    In this paper the spectral mimetic least-squares method is applied to a two-dimensional div-curl system. A test problem is solved on orthogonal and curvilinear meshes and both h- and p-convergence results are presented. The resulting solutions will be pointwise divergence-free for these test

  18. 75 FR 4344 - Foreign-Trade Zone 50-Long Beach, California Application for Subzone Allegro Mfg. Inc. (Cosmetic...

    Science.gov (United States)

    2010-01-27

    ... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [Docket 6-2010] Foreign-Trade Zone 50--Long Beach, California Application for Subzone Allegro Mfg. Inc. (Cosmetic, Organizer and Electronic Bags and Accessories) Commerce, CA An application has been submitted to the Foreign-Trade Zones Board (the Board) by the Port of...

  19. Design information verification (DIV) of closed geological repositories (SAGOR activity 3c)

    International Nuclear Information System (INIS)

    Myatt, J.

    1998-02-01

    Following IAEA Advisory and Consultants Group meetings in September 1988 and in May 1991 respectively an IAEA multi-national Support Programme Task was initiated to consider the 'Development of Safeguards for Final Disposal of Spent Fuel in Geological Repositories' (SAGOR). A 'Technical Coordination Committee' (TCC) was set up with invited representatives from those Member State Support Programmes wishing to be involved. The joint programme, through the TCC, was given the task of studying the safeguards requirements in: conditioning plant (where the spent fuel is prepared for transfer to the repository); operating repositories (i.e. those in which the fuel is being emplaced); closed repositories. At the first meeting of the TCC in Washington in July 1994 the UK undertook to provide a study of the Design Information Verification (DIV) required in all three areas. For this activity the requirements, techniques and procedures for the Design Information Verification (DIV) of closed repositories have been considered. In completing the study the findings reported for activities 1b/c and 2c (descriptions of a Model Repository and Potential Diversion Paths, respectively) have been used in formulating any conclusions reached. It is also debatable as to whether this activity is strictly speaking DIV or is one of surveillance. As undeclared access can only be made to the emplacement areas of the repository by altering the physical makeup of the surrounding area; i.e. physically changing the 'design' of the surrounding area, however, this is deemed to be DIV. Although the techniques used appear to be those of surveillance they are being applied in this case as the tools of DIV. As with any facility there are a number of stages in its lifetime. For the purposes of this report the operating life of a repository is defined as being the time from inception to when it is finally decommissioned and sealed with the ground surface returned to being a green field. The repository is

  20. Accurate macromolecular crystallographic refinement: incorporation of the linear scaling, semiempirical quantum-mechanics program DivCon into the PHENIX refinement package

    Energy Technology Data Exchange (ETDEWEB)

    Borbulevych, Oleg Y.; Plumley, Joshua A.; Martin, Roger I. [QuantumBio Inc., 2790 West College Avenue, State College, PA 16801 (United States); Merz, Kenneth M. Jr [University of Florida, Gainesville, Florida (United States); Westerhoff, Lance M., E-mail: lance@quantumbioinc.com [QuantumBio Inc., 2790 West College Avenue, State College, PA 16801 (United States)

    2014-05-01

    Semiempirical quantum-chemical X-ray macromolecular refinement using the program DivCon integrated with PHENIX is described. Macromolecular crystallographic refinement relies on sometimes dubious stereochemical restraints and rudimentary energy functionals to ensure the correct geometry of the model of the macromolecule and any covalently bound ligand(s). The ligand stereochemical restraint file (CIF) requires a priori understanding of the ligand geometry within the active site, and creation of the CIF is often an error-prone process owing to the great variety of potential ligand chemistry and structure. Stereochemical restraints have been replaced with more robust functionals through the integration of the linear-scaling, semiempirical quantum-mechanics (SE-QM) program DivCon with the PHENIX X-ray refinement engine. The PHENIX/DivCon package has been thoroughly validated on a population of 50 protein–ligand Protein Data Bank (PDB) structures with a range of resolutions and chemistry. The PDB structures used for the validation were originally refined utilizing various refinement packages and were published within the past five years. PHENIX/DivCon does not utilize CIF(s), link restraints and other parameters for refinement and hence it does not make as many a priori assumptions about the model. Across the entire population, the method results in reasonable ligand geometries and low ligand strains, even when the original refinement exhibited difficulties, indicating that PHENIX/DivCon is applicable to both single-structure and high-throughput crystallography.

  1. Effects of parental emotional warmth on the relationship between regional gray matter volume and depression-related personality traits.

    Science.gov (United States)

    Yang, Junyi; Yin, Ping; Wei, Dongtao; Wang, Kangcheng; Li, Yongmei; Qiu, Jiang

    2017-06-01

    The depression-related personality trait is associated with the severity of patients' current depressive symptoms and with the vulnerability to depression within the nonclinical groups. However, little is known about the anatomical structure associated with the depression-related personality traits within the nonclinical sample. Parenting behavior is associated with the depression symptoms; however, whether or not parenting behavior influence the neural basis of the depression-related personality traits is unclear. Thus in current study, first, we used voxel-based morphometry to identify the brain regions underlying individual differences in depression-related personality traits, as measured by the revised Neuroticism-Extraversion-Openness Personality Inventory, in a large sample of young healthy adults. Second, we use mediation analysis to investigate the relationship between parenting behavior and neural basis of depression-related personality traits. The results revealed that depression-related personality traits were positively correlated with gray matter volume mainly in medial frontal gyrus (MFG) that is implicated in the self-referential processing and emotional regulation. Furthermore, parental emotional warmth acted as a mediational mechanism underlying the association between the MFG volume and the depression-related personality trait. Together, our findings suggested that the family environment might play an important role in the acquisition and process of the depression-related personality traits.

  2. Comparison of two psycho-educational family group interventions for improving psycho-social outcomes in persons with spinal cord injury and their caregivers: a randomized-controlled trial of multi-family group intervention versus an active education control condition.

    Science.gov (United States)

    Dyck, Dennis G; Weeks, Douglas L; Gross, Sarah; Lederhos Smith, Crystal; Lott, Hilary A; Wallace, Aimee J; Wood, Sonya M

    2016-07-26

    Over 12,000 individuals suffer a spinal cord injury (SCI) annually in the United States, necessitating long-term, complex adjustments and responsibilities for patients and their caregivers. Despite growing evidence that family education and support improves the management of chronic conditions for care recipients as well as caregiver outcomes, few systematic efforts have been made to involve caregivers in psycho-educational interventions for SCI. As a result, a serious gap exists in accumulated knowledge regarding effective, family-based treatment strategies for improving outcomes for individuals with SCI and their caregivers. The proposed research aims to fill this gap by evaluating the efficacy of a structured adaptation of an evidence-based psychosocial group treatment called Multi-Family Group (MFG) intervention. The objective of this study is to test, in a randomized-controlled design, an MFG intervention for the treatment of individuals with SCI and their primary caregivers. Our central hypothesis is that by providing support in an MFG format, we will improve coping skills of persons with SCI and their caregivers as well as supportive strategies employed by caregivers. We will recruit 32 individuals with SCI who have been discharged from inpatient rehabilitation within the previous 3 years and their primary caregivers. Patient/caregiver pairs will be randomized to the MFG intervention or an active SCI education control (SCIEC) condition in a two-armed randomized trial design. Participants will be assessed pre- and post-program and 6 months post-program. Intent to treat analyses will test two a priori hypotheses: (1) MFG-SCI will be superior to SCIEC for SCI patient activation, health status, and emotion regulation, caregiver burden and health status, and relationship functioning, and (2) MFG will be more effective for individuals with SCI and their caregivers when the person with SCI is within 18 months of discharge from inpatient rehabilitation compared

  3. Cleareye In-Ground and In-Concrete DIV Inspections: FY11 Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Braatz, Brett G.; Tedeschi, Jonathan R.; Denslow, Kayte M.; Morra, Marino; Knopik, Clint D.; Severtsen, Ronald H.; Jones, Anthony M.; Lechelt, Wayne M.; McMakin, Douglas L.; Good, Morris S.; Sorensen, Jerry B.; Hall, Thomas E.

    2012-01-23

    This report summarizes the results of a series of feasibility testing studies for in-ground and in-concrete imaging/detection technologies including radar imaging and acoustic time-of flight method. The objectives of this project are: (1) Design Information Verification (DIV) Tools for In-Concrete Inspections - To determine the feasibility of using holographic radar imaging (HRI), radar imaging, and acoustic time-of-flight (TOF) non-destructive evaluation technologies to detect, locate and identify pipes and voids embedded in standard-density and high-density concrete walls that typify those the IAEA will need to verify during field inspections; (2) DIV Tools for In-Ground Inspections - To determine the feasibility of using HRI and radar imaging non-destructive evaluation technologies to detect, locate, and identify objects buried at various depths made of various materials (metal, plastic, wood, and concrete) and representing geometries that typify those the IAEA will need to verify during field inspections; and (3) Based on the results of the studies, recommend the next steps needed to realize fieldable tools for in-concrete and in-ground inspections (including detection of deeply buried polyvinyl chloride [PVC] pipes) that employ the technologies shown to be feasible.

  4. Accurate macromolecular crystallographic refinement: incorporation of the linear scaling, semiempirical quantum-mechanics program DivCon into the PHENIX refinement package.

    Science.gov (United States)

    Borbulevych, Oleg Y; Plumley, Joshua A; Martin, Roger I; Merz, Kenneth M; Westerhoff, Lance M

    2014-05-01

    Macromolecular crystallographic refinement relies on sometimes dubious stereochemical restraints and rudimentary energy functionals to ensure the correct geometry of the model of the macromolecule and any covalently bound ligand(s). The ligand stereochemical restraint file (CIF) requires a priori understanding of the ligand geometry within the active site, and creation of the CIF is often an error-prone process owing to the great variety of potential ligand chemistry and structure. Stereochemical restraints have been replaced with more robust functionals through the integration of the linear-scaling, semiempirical quantum-mechanics (SE-QM) program DivCon with the PHENIX X-ray refinement engine. The PHENIX/DivCon package has been thoroughly validated on a population of 50 protein-ligand Protein Data Bank (PDB) structures with a range of resolutions and chemistry. The PDB structures used for the validation were originally refined utilizing various refinement packages and were published within the past five years. PHENIX/DivCon does not utilize CIF(s), link restraints and other parameters for refinement and hence it does not make as many a priori assumptions about the model. Across the entire population, the method results in reasonable ligand geometries and low ligand strains, even when the original refinement exhibited difficulties, indicating that PHENIX/DivCon is applicable to both single-structure and high-throughput crystallography.

  5. A weak Galerkin least-squares finite element method for div-curl systems

    Science.gov (United States)

    Li, Jichun; Ye, Xiu; Zhang, Shangyou

    2018-06-01

    In this paper, we introduce a weak Galerkin least-squares method for solving div-curl problem. This finite element method leads to a symmetric positive definite system and has the flexibility to work with general meshes such as hybrid mesh, polytopal mesh and mesh with hanging nodes. Error estimates of the finite element solution are derived. The numerical examples demonstrate the robustness and flexibility of the proposed method.

  6. Apoprotein Structure and Metal Binding Characterization of a de Novo Designed Peptide, α3DIV, that Sequesters Toxic Heavy Metals.

    Science.gov (United States)

    Plegaria, Jefferson S; Dzul, Stephen P; Zuiderweg, Erik R P; Stemmler, Timothy L; Pecoraro, Vincent L

    2015-05-12

    De novo protein design is a biologically relevant approach that provides a novel process in elucidating protein folding and modeling the metal centers of metalloproteins in a completely unrelated or simplified fold. An integral step in de novo protein design is the establishment of a well-folded scaffold with one conformation, which is a fundamental characteristic of many native proteins. Here, we report the NMR solution structure of apo α3DIV at pH 7.0, a de novo designed three-helix bundle peptide containing a triscysteine motif (Cys18, Cys28, and Cys67) that binds toxic heavy metals. The structure comprises 1067 NOE restraints derived from multinuclear multidimensional NOESY, as well as 138 dihedral angles (ψ, φ, and χ1). The backbone and heavy atoms of the 20 lowest energy structures have a root mean square deviation from the mean structure of 0.79 (0.16) Å and 1.31 (0.15) Å, respectively. When compared to the parent structure α3D, the substitution of Leu residues to Cys enhanced the α-helical content of α3DIV while maintaining the same overall topology and fold. In addition, solution studies on the metalated species illustrated metal-induced stability. An increase in the melting temperatures was observed for Hg(II), Pb(II), or Cd(II) bound α3DIV by 18-24 °C compared to its apo counterpart. Further, the extended X-ray absorption fine structure analysis on Hg(II)-α3DIV produced an average Hg(II)-S bond length at 2.36 Å, indicating a trigonal T-shaped coordination environment. Overall, the structure of apo α3DIV reveals an asymmetric distorted triscysteine metal binding site, which offers a model for native metalloregulatory proteins with thiol-rich ligands that function in regulating toxic heavy metals, such as ArsR, CadC, MerR, and PbrR.

  7. Molecular formula and METLIN Personal Metabolite Database matching applied to the identification of compounds generated by LC/TOF-MS.

    Science.gov (United States)

    Sana, Theodore R; Roark, Joseph C; Li, Xiangdong; Waddell, Keith; Fischer, Steven M

    2008-09-01

    In an effort to simplify and streamline compound identification from metabolomics data generated by liquid chromatography time-of-flight mass spectrometry, we have created software for constructing Personalized Metabolite Databases with content from over 15,000 compounds pulled from the public METLIN database (http://metlin.scripps.edu/). Moreover, we have added extra functionalities to the database that (a) permit the addition of user-defined retention times as an orthogonal searchable parameter to complement accurate mass data; and (b) allow interfacing to separate software, a Molecular Formula Generator (MFG), that facilitates reliable interpretation of any database matches from the accurate mass spectral data. To test the utility of this identification strategy, we added retention times to a subset of masses in this database, representing a mixture of 78 synthetic urine standards. The synthetic mixture was analyzed and screened against this METLIN urine database, resulting in 46 accurate mass and retention time matches. Human urine samples were subsequently analyzed under the same analytical conditions and screened against this database. A total of 1387 ions were detected in human urine; 16 of these ions matched both accurate mass and retention time parameters for the 78 urine standards in the database. Another 374 had only an accurate mass match to the database, with 163 of those masses also having the highest MFG score. Furthermore, MFG calculated a formula for a further 849 ions that had no match to the database. Taken together, these results suggest that the METLIN Personal Metabolite database and MFG software offer a robust strategy for confirming the formula of database matches. In the event of no database match, it also suggests possible formulas that may be helpful in interpreting the experimental results.

  8. Analysis of biological spectrum of Divčibare flora

    Directory of Open Access Journals (Sweden)

    Popović Ivana

    2006-01-01

    Full Text Available One of the essential analyses which is performed during the floristic study of a region is the analysis of the biological spectrum. The analysis of the biological spectrum of the flora includes the determination of the type of life form for each taxon described in the flora of the study region. If it is considered that life form is a specific structural-functional response to the environmental effects and the result of the adaptation during the species evolution, it is clear that the basic characteristics of the site are more or less reflected in any life form. This fact is confirmed by the analysis of the biological spectrum of Divčibare flora. The study results are in correlation with the results of the analysis of the biological spectrum of the flora of Serbia and the Balkan Peninsula.

  9. Septal membrane localization by C-terminal amphipathic α-helices of MinD in Bacillus subtilis mutant cells lacking MinJ or DivIVA.

    Science.gov (United States)

    Ishikawa, Kazuki; Matsuoka, Satoshi; Hara, Hiroshi; Matsumoto, Kouji

    2017-10-18

    The Min system, which inhibits assembly of the cytokinetic protein FtsZ, is largely responsible for positioning the division site in rod-shaped bacteria. It has been reported that MinJ, which bridges DivIVA and MinD, is targeted to the cell poles by an interaction with DivIVA, and that MinJ in turn recruits MinCD to the cell poles. MinC, however, is located primarily at active division sites at mid-cell when expressed from its native promoter. Surprisingly, we found that Bacillus subtilis MinD is located at nascent septal membranes and at an asymmetric site on lateral membranes between nascent septal membranes in filamentous cells lacking MinJ or DivIVA. Bacillus subtilis MinD has two amphipathic α-helices rich in basic amino acid residues at its C-terminus; one of these, named MTS1 here, is the counterpart of the membrane targeting sequence (MTS) in Escherichia coli MinD while the other, named MTS-like sequence (MTSL), is the nearest helix to MTS1. These amphipathic helices were located independently at nascent septal membranes in cells lacking MinJ or DivIVA, whereas elimination of the helices from the wild type protein reduced its localization considerably. MinD variants with altered MTS1 and MTSL, in which basic amino acid residues were replaced with proline or acidic residues, were not located at nascent septal membranes, indicating that the binding to the nascent septal membranes requires basic residues and a helical structure. The septal localization of MTSL, but not of MTS1, was dependent on host cell MinD. These results suggest that MinD is targeted to nascent septal membranes via its C-terminal amphipathic α-helices in B. subtilis cells lacking MinJ or DivIVA. Moreover, the diffuse distribution of MinD lacking both MTSs suggests that only a small fraction of MinD depends on MinJ for its localization to nascent septal membranes.

  10. Key Aging-Associated Alterations in Primary Microglia Response to Beta-Amyloid Stimulation

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    Cláudia Caldeira

    2017-08-01

    Full Text Available Alzheimer’s disease (AD is characterized by a progressive cognitive decline and believed to be driven by the self-aggregation of amyloid-β (Aβ peptide into oligomers and fibrils that accumulate as senile plaques. It is widely accepted that microglia-mediated inflammation is a significant contributor to disease pathogenesis; however, different microglia phenotypes were identified along AD progression and excessive Aβ production was shown to dysregulate cell function. As so, the contribution of microglia to AD pathogenesis remains to be elucidated. In this study, we wondered if isolated microglia cultured for 16 days in vitro (DIV would react differentially from the 2 DIV cells upon treatment with 1000 nM Aβ1–42 for 24 h. No changes in cell viability were observed and morphometric alterations associated to microglia activation, such as volume increase and process shortening, were obvious in 2 DIV microglia, but less evident in 16 DIV cells. These cells showed lower phagocytic, migration and autophagic properties after Aβ treatment than the 2 DIV cultured microglia. Reduced phagocytosis may derive from increased CD33 expression, reduced triggering receptor expressed on myeloid cells 2 (TREM2 and milk fat globule-EGF factor 8 protein (MFG-E8 levels, which were mainly observed in 16 DIV cells. Activation of inflammatory mediators, such as high mobility group box 1 (HMGB1 and pro-inflammatory cytokines, as well as increased expression of Toll-like receptor 2 (TLR2, TLR4 and fractalkine/CX3C chemokine receptor 1 (CX3CR1 cell surface receptors were prominent in 2 DIV microglia, while elevation of matrix metalloproteinase 9 (MMP9 was marked in 16 DIV cells. Increased senescence-associated β-galactosidase (SA-β-gal and upregulated miR-146a expression that were observed in 16 DIV cells showed to increase by Aβ in 2 DIV microglia. Additionally, Aβ downregulated miR-155 and miR-124, and reduced the CD11b+ subpopulation in 2 DIV microglia, while

  11. Changes of hyoid bone position following treatment of class II div1 malocclusion with Farmand functional appliance

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    Yassaei S

    2007-01-01

    Full Text Available Background and Aim: Unlike other bones of the head and neck, hyoid bone has no bony articulations. It is connected to mandible, cranium and pharynx through muscles and ligaments. During treatment with functional appliance in patients with class II div1 malocclusion, mandible is positioned in inferior and anterior direction. Regarding the relation between hyoid and mandibular bone, alterations of hyoid bone position can be a result of functional appliance therapy. The aim of this study was to evaluate the changes of hyoid bone position following treatment with Farmand functional appliance in patients with class II div 1 malocclusion. Materials and Methods: In this before-after clinical trial, 28 patients with class II div 1 malocclusion which were under treatment with Farmand functional appliance for 11 months were selected. Facial growth in vertical, normal or horizontal direction was determined by cephalometric measurement. Data were analyzed with Paired-t test to compare the differences of mean values pre and post treatment. Variance analysis was used to compare the three growth patterns. P<0.05 was considered as the limit of significance. Results: Hyoid bone shifted significantly forward in horizontal dimension (P<0.01 and non-significantly upward in vertical dimension. There was no significant difference among the three studied groups with respect to hyoid bone position alterations in horizontal dimension but significant difference was observed between horizontal and vertical growth pattern in vertical dimension (P<0.05. There was significant correlation between decrease of ANB angle and forward movement of hyoid bone. Conclusion: Based on the results of this study, treatment with Farmand functional appliance (Fa II leads to significant alterations in the position and anterior displacement of the hyoid bone.

  12. Divórcio e funcionamento psicológico em adultos e crianças

    OpenAIRE

    Silva, Diogo Jorge Pereira do Vale Lamela da

    2013-01-01

    Tese de doutoramento em Psicologia (área de especialização de Psicologia Clínica) A presente dissertação foi orientada por dois enquadramentos teóricos: o modelo de Desenvolvimento Positivo da Personalidade na idade adulta (Staudinger & Bowen, 2010) e no modelo ecológico da coparentalidade (Feinberg, 2003). Objetivo: Este trabalho pretendeu responder a quatro objetivos. (1) Identificar variáveis sócio-demográficas, características do divórcio e indicadores personológicos qu...

  13. Efficient augmented Lagrangian-type preconditioning for the Oseen problem using Grad-Div stabilization

    KAUST Repository

    Heister, Timo

    2012-01-29

    Efficient preconditioning for Oseen-type problems is an active research topic. We present a novel approach leveraging stabilization for inf-sup stable discretizations. The Grad-Div stabilization shares the algebraic properties with an augmented Lagrangian-type term. Both simplify the approximation of the Schur complement, especially in the convection-dominated case. We exploit this for the construction of the preconditioner. Solving the discretized Oseen problem with an iterative Krylov-type method shows that the outer iteration numbers are retained independent of mesh size, viscosity, and finite element order. Thus, the preconditioner is very competitive. © 2012 John Wiley & Sons, Ltd.

  14. Efficient augmented Lagrangian-type preconditioning for the Oseen problem using Grad-Div stabilization

    KAUST Repository

    Heister, Timo; Rapin, Gerd

    2012-01-01

    Efficient preconditioning for Oseen-type problems is an active research topic. We present a novel approach leveraging stabilization for inf-sup stable discretizations. The Grad-Div stabilization shares the algebraic properties with an augmented Lagrangian-type term. Both simplify the approximation of the Schur complement, especially in the convection-dominated case. We exploit this for the construction of the preconditioner. Solving the discretized Oseen problem with an iterative Krylov-type method shows that the outer iteration numbers are retained independent of mesh size, viscosity, and finite element order. Thus, the preconditioner is very competitive. © 2012 John Wiley & Sons, Ltd.

  15. SiDIVS: Simple Detection of Inductive Vehicle Signatures with a Multiplex Resonant Sensor

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    José J. Lamas-Seco

    2016-08-01

    Full Text Available This work provides a system capable of obtaining simultaneous inductive signatures of vehicles traveling on a roadway with minimal cost. Based on Time-Division Multiplexing (TDM with multiple oscillators, one for each inductive loop, the proposed system detects the presence of vehicles by means of a shift in the oscillation period of the selected loop and registers the signature of the detected vehicles by measuring the duration of a fixed number of oscillator pulses. In order to test the system in an actual environment, we implement a prototype that we denote as SiDIVS (Simple Detection of Inductive Vehicle Signatures and acquire different vehicle inductive signatures under real scenarios. We also test the robustness of the detector by simulating the effect of noise on the signature acquisition.

  16. Animais, divórcio e consequências jurídicas

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    Camilo Henrique Silva

    2015-07-01

    Full Text Available http://dx.doi.org/10.5007/1807-1384.2015v12n1p102 O presente trabalho, por meio da pesquisa bibliográfica às leis, às decisões judiciais e à doutrina, tem por escopo trazer ao leitor, de maneira objetiva, as reflexões e o posicionamento do ordenamento jurídico brasileiro sobre o tema dos animais de estimação envolvidos em disputas de guarda no processo de divórcio. Nesse contexto, o escrito aborda a lei brasileira sobre guarda, direito de visita e alimentos, e sua utilização, por analogia, aos casos envolvendo animais de estimação, em razão da falta de norma específica. O texto retrata a tarefa dos magistrados e tribunais de se posicionarem nos casos levados a juízo e apresenta requisitos a serem observados para a decisão da lide, com vistas ao bem-estar e interesse do animal. Na disputa judicial pelos animais de estimação é legal a concessão da guarda e direito de visita aos cônjuges-tutores e a imposição de prestar alimentos ao animal.

  17. Reduced cortical thickness and increased surface area in antisocial personality disorder.

    Science.gov (United States)

    Jiang, Weixiong; Li, Gang; Liu, Huasheng; Shi, Feng; Wang, Tao; Shen, Celina; Shen, Hui; Lee, Seong-Whan; Hu, Dewen; Wang, Wei; Shen, Dinggang

    2016-11-19

    Antisocial personality disorder (ASPD), one of whose characteristics is high impulsivity, is of great interest in the field of brain structure and function. However, little is known about possible impairments in the cortical anatomy in ASPD, in terms of cortical thickness (CTh) and surface area (SA), as well as their possible relationship with impulsivity. In this neuroimaging study, we first investigated the changes of CTh and SA in ASPD patients, in comparison to those of healthy controls, and then performed correlation analyses between these measures and the ability of impulse control. We found that ASPD patients showed thinner cortex while larger SA in several specific brain regions, i.e., bilateral superior frontal gyrus (SFG), orbitofrontal and triangularis, insula cortex, precuneus, middle frontal gyrus (MFG), middle temporal gyrus (MTG), and left bank of superior temporal sulcus (STS). In addition, we also found that the ability of impulse control was positively correlated with CTh in the SFG, MFG, orbitofrontal cortex (OFC), pars triangularis, superior temporal gyrus (STG), and insula cortex. To our knowledge, this study is the first to reveal simultaneous changes in CTh and SA in ASPD, as well as their relationship with impulsivity. These cortical structural changes may introduce uncontrolled and callous behavioral characteristic in ASPD patients, and these potential biomarkers may be very helpful in understanding the pathomechanism of ASPD. Copyright © 2016 IBRO. Published by Elsevier Ltd. All rights reserved.

  18. Investigation of the Stress Intensity Limits of ASME Section III Div.5 for Structure Design Criteria of SFR Fuel Assembly

    Energy Technology Data Exchange (ETDEWEB)

    Choo, Jin-Yup; Kim, Hyung-Kyu; Cheon, Jin-Sik [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2016-10-15

    These affect the mechanical design of the fuel assembly components. And thus, appropriate structural design criteria should also be chosen to incorporate the specific design conditions of the SFR fuel assemblies. Among them, the temperature is one of the most crucial conditions to be concerned because the sodium coolant temperature is normally more than 500ºC which is much higher than that of the LWR (< 350ºC). This implies that a thermal creep should be significantly considered in the SFR fuel assembly mechanical design. In addition to the high temperature condition, an irradiation swelling is also an important behavior that the SFR fuel assembly material should accommodate. To incorporate the temperature and irradiation impacts, the material of the fuel assembly components is presently determined to be made of HT-9, the ferriticmartensitic steel. In this paper, the ASME Sec. III Div. 5 (referred to as ‘Div. 5’ hereinafter), which was developed for a ‘high temperature reactor’, is considered as one of the structural design criteria for the mechanical design of SFR fuel assemblies. In this paper, the stress intensity limits, S{sub m} and S{sub t} of HT-9 were built for the structural criteria of an SFR fuel assembly. S{sub m} is obtained from the ultimate strength. As for S{sub t}, it is more complicated because of its dependency of time duration in addition to temperature. Following the definition of S{sub mt}, the method in the ASME Sec. III Div. 1, Subsec. NH was consulted. We found that the Sm is adopted as S{sub mt} under the temperature about 470ºC which is relatively low temperature range and over 470ºC with relatively short time duration as 1000 hours. And the S{sub t} is adopted as Smt at over 470ºC and long time duration over 34800 hours, and over 520ºC and 10{sup 4} hours too. And at over 570ºC and 1000 hours, and at over 630ºC and 100 hours, S{sub t} is also adopted for S{sub mt}.

  19. The Italian forest sites of FunDivEUROPE: a new FP7 project on the functional significance of forest biodiversity in Europe

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    Bussotti F

    2012-12-01

    Full Text Available The Italian forest sites of FunDivEUROPE: a new FP7 project on the functional significance of forest biodiversity in Europe. FunDivEUROPE is a new project aiming at a deeper understanding of the role of forest diversity on ecosystem functions and service provisioning for society. This project combines three scientific platforms: experimental, exploratory and inventory. The exploratory platform is based on the observation of a broad range of properties, traits and ecological processes on a network of ca. 240 natural forest sites representing a gradient of tree species diversity in six focal regions of Europe (Spain, Italy, Germany, Poland, Finland and Romania. The Italian sites are located on the hills of central and Southern Tuscany and represent the category “thermophilous deciduous forest”. Almost one year of fieldwork was needed to select and characterize 36 plots measuring 30 x 30 m. Selection was based on criteria concerning tree mixtures and richness, structural parameters and main environmental variables. The main features of these sites are synthetically presented in this paper together with a short description of the project structure and scope. The aim is also to enhance dissemination of the potential implications for a sustainable forest management in Italy.

  20. Assessment of the dentoskeletal changes following the use of twin-block functional appliance and inclined anterior bite plan in the patients with class II malocclusion div 1 in 11-14 years old

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    Allahyar Geramy

    2015-12-01

    Full Text Available Background and Aims: Cl II malocclusion is one of the most common abnormalities in human societies and using a simple, affordable and accessible treatment that can be provided by general practitioners or specialists, to prevent future malocclusion complications is vital. Cl II malocclusion treatment using functional appliances such as twin block and anterior inclined bite plan have less cost, side effects and complications compared to fixed orthodontic or orthosurgery. Until now, the dentoskeletal changes resulting from the application of twin block and anterior inclined bite plan in patients with Class II malocclusion has not been evaluated. The objective of the present study was to assess the dentoskeletal changes following the use of twin-block functional appliance and inclined anterior bite plan in the patients with class II malocclusion div 1 during mixed dentition. Materials and Methods: In this retrospective cohort trial, 60 patients with the definitive diagnosis of Class II div. 1 malocclusion having ANB>2 and FMA angel between 20 and 30 and without any previous treatment or syndrome who were treated with twin-block or inclined anterior bite plan appliance were selected and their lateral cephalometries were traced before and after treatment. Selected distance and angular landmarks were measured on the cephalograms with the good reliability (ICC=0.953 and the changes occurred in the landmarks were statistically analyzed using Student t test. Results: Due to the increased mandibular growth, most of the landmarks experienced significant changes following the treatment with twin-block and inclined bite plan (P0.05, however, SNA (P=0.04, overjet (P=0.007 and wits appraisal (P=0.004 changed differently after using the appliances. Conclusion: Despite with most similarities of both twin-block and anterior inclined bite plan to correct class II div. 1 malocclusion, Due to the advantages of anterior inclined bite plan such as less size, good

  1. Adaptação ao divórcio e relações coparentais: contributos da teoria da vinculação Adjustment to divorce and co-parental relations: contributions from the theory of attachment

    Directory of Open Access Journals (Sweden)

    Diogo Lamela

    2010-01-01

    Full Text Available Neste artigo propõe-se uma contribuição da teoria da vinculação na compreensão dos processos de adaptação dos adultos ao seu divórcio e como a desvinculação ao ex-cônjuge interfere na coparentalidade pós-divórcio. Este artigo formula duas hipóteses teóricas. A primeira hipótese afirma que o divórcio, enquanto processo relacional, deve ser lido como um momento de perda que germina reacções psicológicas similares às experienciadas pelos viúvos, tal como descreve Bowlby no modelo de perda da figura de vinculação, estando dependente dos estilos de vinculação dos adultos. A segunda hipótese sustenta que a coparentalidade pós-divórcio é predita pelos estilos de vinculação e pela qualidade da reorganização da vinculação dos pais. Finalmente, uma integração teórica é apresentada, operacionalizada numa proposta de investigação futura neste domínio.In this article, it is proposed the contribution of the attachment theory for understanding adults' adjustment processes to their divorce and how detachment to ex-spouse can infer in co-parenting relationships after marital dissolution. This article makes two theoretical assumptions that focus on two dimensions. The first hypothesis states that the divorce, while a relational process, should be read as a moment of loss that germinates similar psychological reactions to those experienced by widows. Bowlby describes it in his model of loss of the attachment figure as dependent on attachment styles of divorced adults. The second hypothesis argues that the post-divorce co-parenting relationships are predicted by the attachment styles and by the quality of parents' attachment reorganization. At the end, a theoretical integration is built, based on a proposal for future research in this area.

  2. As Bruxas no Divã: o desafio de ser criativo e ousar no ensino de artes

    Directory of Open Access Journals (Sweden)

    Marcelo Rossa

    2012-11-01

    Este artigo relata o projeto “As Bruxas no Divã”, que consiste na produção de um filme no Instituto Estadual de Educação (IEE escola da rede estadual de ensino de SC. Nele introduziu-se a linguagem cinematográfica na Educação Infantil, contribuindo no processo de ensino e aprendizagem de Artes. O objetivo deste projeto foi desenvolver uma vivência dentro das diversas linguagens artísticas, bem como aguçar a reflexão sobre questões existenciais da vida. O projeto oportunizou a utilização de diversas linguagens artísticas bem como as novas tecnologias. A motivação para seu desenvolvimento foi à literatura e a produção de cinema amador infantil e se mostraram uma forma de comunicação apta a estabelecer interdisciplinaridade de várias áreas do conhecimento de forma criativa e harmoniosa.

  3. O envolvimento parental após a separação/divórcio Parental involvement after separation/divorce

    Directory of Open Access Journals (Sweden)

    Luciana Suárez Grzybowski

    2010-01-01

    Full Text Available Apoiados no modelo ecológico-contextual e no conceito de envolvimento parental, este artigo se propõe a discutir as práticas parentais de pais e mães separados/divorciados com seus filhos. Para tanto, foram pesquisados 234 sujeitos (117 pais/117 mães com filhos em idade escolar, que responderam o Inventário de Práticas Parentais. Tal instrumento avaliou o envolvimento parental em 5 áreas: envolvimento afetivo, envolvimento didático, envolvimento social, envolvimento disciplinar e responsabilidade. Os resultados evidenciam maior envolvimento materno do que paterno com os filhos após o divórcio, tanto direto (cuidados, interação quanto indireto (monitoramento, preocupação. A coabitação com a mãe mostrou ser uma variável significativa associada ao maior envolvimento dela em atividades no espaço privado/doméstico, enquanto os pais tiveram maior envolvimento no espaço público/social. Características contextuais (coabitação, freqüência de visitas e características dos pais (ocupação, escolaridade, questões afetivo-conjugais mostraram-se fortemente associadas ao envolvimento parental após o divórcio.Based on the ecological-contextual model and on the concept of parental involvement, this article proposes to discuss the parental practices of separated/divorced fathers and mothers towards their children. In order to do so, 234 subjects (117 fathers/117 mothers with children at school were interviewed via the Parental Practices Inventory. Such instrument evaluated the parental involvement in 5 areas: affective involvement, didactic involvement, social involvement, disciplinary involvement and, responsibility. The results showed greater maternal involvement with children after the divorce: direct (care, interaction and indirect (monitoring, preoccupation. The cohabitation with the mother revealed itself as a significant variable associated to her greater involvement with activities in the private/domestic environment while

  4. Interdisciplinary management of an adult patient with class II div 1 Malocclusion, Anterior Open Bite and multiple missing molars

    Directory of Open Access Journals (Sweden)

    Rohit Mehrotra

    2014-01-01

    Full Text Available This case report describes the esthetic and functional rehabilitation of a female patient in her mid forties having Class II Div 1 malocclusion, anterior open bite and multiple missing molars, with orthodontics and implant prosthodontics. The patient had bilaterally missing upper first and third molars and lower first and second molars. Orthodontic treatment using skeletal anchorage was performed to retract and align the upper anteriors and correct the open bite. In the upper arch, first molar spaces were closed and no prosthesis was needed. In the lower arch, the anteriors and premolars were aligned and implants were placed bilaterally to replace the missing molars and provide proper occlusion with the upper posteriors. Significant improvement in the occlusion, smile and facial esthetics was achieved. This article highlights the importance of an interdisciplinary team approach for providing optimum treatment to many adult patients.

  5. Gray matter volume reduction in rostral middle frontal gyrus in patients with chronic schizophrenia.

    Science.gov (United States)

    Kikinis, Z; Fallon, J H; Niznikiewicz, M; Nestor, P; Davidson, C; Bobrow, L; Pelavin, P E; Fischl, B; Yendiki, A; McCarley, R W; Kikinis, R; Kubicki, M; Shenton, M E

    2010-11-01

    The dorsolateral prefrontal cortex (DLPFC) is a brain region that has figured prominently in studies of schizophrenia and working memory, yet the exact neuroanatomical localization of this brain region remains to be defined. DLPFC primarily involves the superior frontal gyrus and middle frontal gyrus (MFG). The latter, however is not a single neuroanatomical entity but instead is comprised of rostral (anterior, middle, and posterior) and caudal regions. In this study we used structural MRI to develop a method for parcellating MFG into its component parts. We focused on this region of DLPFC because it includes BA46, a region involved in working memory. We evaluated volume differences in MFG in 20 patients with chronic schizophrenia and 20 healthy controls. Mid-rostral MFG (MR-MFG) was delineated within the rostral MFG using anterior and posterior neuroanatomical landmarks derived from cytoarchitectonic definitions of BA46. Gray matter volumes of MR-MFG were then compared between groups, and a significant reduction in gray matter volume was observed (p<0.008), but not in other areas of MFG (i.e., anterior or posterior rostral MFG, or caudal regions of MFG). Our results demonstrate that volumetric alterations in MFG gray matter are localized exclusively to MR-MFG. 3D reconstructions of the cortical surface made it possible to follow MFG into its anterior part, where other approaches have failed. This method of parcellation offers a more precise way of measuring MR-MFG that will likely be important in further documentation of DLPFC anomalies in schizophrenia. Copyright © 2010 Elsevier B.V. All rights reserved.

  6. The neuroprotective effects of milk fat globule-EGF factor 8 against oligomeric amyloid β toxicity

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    Li Endong

    2012-06-01

    Full Text Available Abstract Background Phosphatidylserine receptor is a key molecule that mediates the phagocytosis of apoptotic cells. Milk fat globule-EGF factor 8 (MFG-E8 is a phosphatidylserine receptor that is expressed on various macrophage lineage cells, including microglia in the central nervous system (CNS. Targeted clearance of degenerated neurons by microglia is essential to maintain healthy neural networks. We previously showed that the CX3C chemokine fractalkine is secreted from degenerated neurons and accelerates microglial clearance of neuronal debris via inducing the release of MFG-E8. However, the mechanisms by which microglia produce MFG-E8 and the precise functions of MFG-E8 are unknown. Methods The release of MFG-E8 from microglia treated with conditioned medium from neurons exposed to neurotoxic substances, glutamate or oligomeric amyloid β (oAβ was measured by ELISA. The neuroprotective effects of MFG-E8 and MFG-E8 − induced microglial phagocytosis of oAβ were assessed by immunocytochemistry. The effects of MFG-E8 on the production of the anti-oxidative enzyme hemeoxygenase-1 (HO-1 were determined by ELISA and immunocytochemisty. Results MFG-E8 was induced in microglia treated with conditioned medium from neurons that had been exposed to neurotoxicants, glutamate or oAβ. MFG-E8 significantly attenuated oAβ-induced neuronal cell death in a primary neuron − microglia coculture system. Microglial phagocytosis of oAβ was accelerated by MFG-E8 treatment due to increased CD47 expression in the absence of neurotoxic molecule production, such as tumor necrosis factor-α, nitric oxide, and glutamate. MFG-E8 − treated microglia induced nuclear factor E(2 − related factor 2 (Nrf2 − mediated HO-1 production, which also contributed to neuroprotection. Conclusions These results suggest that microglia release MFG-E8 in response to signals from degenerated neurons and that MFG-E8 protects oAβ-induced neuronal cell death

  7. Two numerical methods for mean-field games

    KAUST Repository

    Gomes, Diogo A.

    2016-01-01

    Here, we consider numerical methods for stationary mean-field games (MFG) and investigate two classes of algorithms. The first one is a gradient flow method based on the variational characterization of certain MFG. The second one uses monotonicity properties of MFG. We illustrate our methods with various examples, including one-dimensional periodic MFG, congestion problems, and higher-dimensional models.

  8. Two Numerical Approaches to Stationary Mean-Field Games

    KAUST Repository

    Almulla, Noha; Ferreira, Rita; Gomes, Diogo A.

    2016-01-01

    Here, we consider numerical methods for stationary mean-field games (MFG) and investigate two classes of algorithms. The first one is a gradient-flow method based on the variational characterization of certain MFG. The second one uses monotonicity properties of MFG. We illustrate our methods with various examples, including one-dimensional periodic MFG, congestion problems, and higher-dimensional models.

  9. Two numerical methods for mean-field games

    KAUST Repository

    Gomes, Diogo A.

    2016-01-09

    Here, we consider numerical methods for stationary mean-field games (MFG) and investigate two classes of algorithms. The first one is a gradient flow method based on the variational characterization of certain MFG. The second one uses monotonicity properties of MFG. We illustrate our methods with various examples, including one-dimensional periodic MFG, congestion problems, and higher-dimensional models.

  10. Two Numerical Approaches to Stationary Mean-Field Games

    KAUST Repository

    Almulla, Noha

    2016-10-04

    Here, we consider numerical methods for stationary mean-field games (MFG) and investigate two classes of algorithms. The first one is a gradient-flow method based on the variational characterization of certain MFG. The second one uses monotonicity properties of MFG. We illustrate our methods with various examples, including one-dimensional periodic MFG, congestion problems, and higher-dimensional models.

  11. Tratamento cirúrgico da comunicação interventricular e rotura da parede livre do ventrículo esquerdo após infarto agudo do miocárdio e da disjunção atrioventricular após troca da valva mitral, empregando o dispositivo de isolamento ventricular (DIV:: estudo experimental

    Directory of Open Access Journals (Sweden)

    BERNARDES Rodrigo de Castro

    1997-01-01

    Full Text Available A rotura de parede livre do ventrículo esquerdo (VE e a comunicação interventricular (CIV por rotura de septo são dois eventos catastróficos que podem complicar a evolução do infarto agudo do miocárdio (IAM. A oportunidade do tratamento cirúrgico, o acesso à CIV e a técnica cirúrgica ideal para o tratamento desta complicação são muito discutidos na literatura (1-5. Os resultados, porém, são quase unânimes: alta taxa de mortalidade. A rotura da parede posterior do ventrículo esquerdo pós troca da valva mitral (disjunção atrioventricular não é uma complicação rara, sendo quase sempre fatal (6, 7. O objetivo de nosso trabalho é discutir a alternativa de tratamento cirúrgico destas graves lesões, sem o manuseio direto do músculo cardíaco friável, necrozado. Desenvolvemos e testamos em animais (carneiros o dispositivo de isolamento ventricular (DIV. No período de 12/7/95 a 10/1/96, operamos 12 carneiros adultos para o implante do DIV. No primeiro período de aprendizado da técnica de implante e de desenvolvimento da prótese, operamos 7 animais, sem sucesso. No segundo período operamos 5 animais, já com o DIV completamente desenvolvido e com a técnica cirúrgica já padronizada; obtivemos sucesso com todos os animais, sobrevivendo com bom débito cardíaco, constatado ao ecocardiograma e à ventriculografia. Após 20 dias de sobrevida, os animais foram submetidos a ventriculografia e ecocardiografia. Observamos o completo isolamento da cavidade ventricular com o emprego do DIV, obtendo o tratamento provisório destas graves lesões.

  12. Investigation of the Stress Intensity Limits of ASME Section III Div.5 for Structure Design Criteria of SFR Fuel Assembly

    International Nuclear Information System (INIS)

    Choo, Jin-Yup; Kim, Hyung-Kyu; Cheon, Jin-Sik

    2017-01-01

    In this paper, the stress intensity limits, Sm and St of HT-9 were built for the structural criteria of an SFR fuel assembly. Sm is obtained from the ultimate strength. As for St, it is more complicated because of its dependency of time duration in addition to temperature. Following the definition of Smt, the method in the ASME Sec. III Div. 1, Subsec. NH was consulted. We found that the Sm is adopted as Smt under the temperature about 470 .deg. C which is relatively low temperature range and over 470 .deg. C with relatively short time duration as 1000 hours. And the St is adopted as Smt at over 470 .deg. C and long time duration over 34800 hours, and over 520 .deg. C and 104 hours too. And at over 570 .deg. C and 1000 hours, and at over 630 .deg. C and 100 hours, St is also adopted for Smt. To use the present result as design criteria, a stringent examination needs to be carried out, because those are calculated from the formulae of HT-9 without an experimental validation. Therefore, an experimental work on the mechanical properties of HT-9 will be necessary.

  13. Entrevista - Crise do Capital, disputa de destino e desafios para os trabalhadores

    Directory of Open Access Journals (Sweden)

    Reinaldo Gonçalves

    2010-05-01

    Full Text Available <div>Desde 2007, temos acompanhado as notícias sobre a mais profunda crise dodiv>>capitalismo, segundo analistas de todos os matizes, desde a grande depressão dediv>>1929. A crise tem seu estopim no mercado financeiro, por meio do esgotamentodiv>>do crédito, e no epicentro do sistema, a potência econômico-militar norteamericana.div>>E se alastra obrigando muitos que dormiram neoliberais num dia adiv>>acordarem keynesianos no outro, reivindicando mais do que nunca o suporte dodiv>>fundo público dos Estados nacionais. A crise abre uma onda de falências,div>>concordatas, aquisições e fusões, num profundo processo de concentração dediv>>capitais, no mesmo passo em que o desemprego se alastra como uma epidemia.div>>As manifestações de trabalhadores na Europa e nos Estados Unidos no dia 1o dediv>>maio de 2009, muitas delas radicalizadas e unificadas como há muito não se via,div>>não deixam dúvidas sobre o impacto da crise sobre os trabalhadores, quediv>>buscam recompor sua organização política após anos de fragmentação,div>>complexificação e heterogeneização. A profundidade da crise foi subestimada nodiv>>Brasil supostamente blindado pela gestão eficiente da política econômica,div>>articulada à transferência de renda como eixo da política social. Será? Paradiv>>comentar esses processos e alimentar nossa compreensão de seus significados ediv>>repercussões presentes e futuras, convidamos o economista Reinaldo Gonçalves,div>>professor titular de Economia Internacional da UFRJ, autor de mais de trêsdiv>>centenas de trabalhos publicados em 21 países, e com nove livros publicados nodiv>>Brasil, em geral sobre a economia política brasileira e sua relação com o cenáriodiv>>internacional. Reinaldo Gonçalves nos alerta para a longa duração desta crise ediv>>para a fragilidade das

  14. Intermittent Dosing of Micafungin Is Effective for Treatment of Experimental Disseminated Candidiasis in Persistently Neutropenic Rabbits.

    Science.gov (United States)

    Petraitiene, Ruta; Petraitis, Vidmantas; Hope, William W; Walsh, Thomas J

    2015-12-01

    The current standard of treatment of invasive candidiasis with echinocandins requires once-daily therapy. To improve quality of life, reduce costs, and improve outcome, we studied the pharmacokinetics (PK), efficacy, and safety of alternate dosing regimens of micafungin (MFG) for the treatment of experimental subacute disseminated candidiasis. MFG was administered for 12 days starting 24 hours after intravenous inoculation of 1 × 10(3) Candida albicans blastoconidia. Study groups consisted of MFG at 1 mg/kg every 24 hours (MFG1), 2 mg/kg every 48 hours (MFG2), and 3 mg/kg every 72 hours (MFG3), and untreated controls. PK of MFG were determined on day 7 by high-performance liquid chromatography and modeled using nonparametric adaptive grid program. A 2-compartment PK model with volume of the central compartment (Vc), clearance (SCL), and the intercompartmental rate constants Kcp and Kpc was used. The fungal burden in 7 tissues was determined 312 hours after the initiation of therapy. PK of MFG were linear and the parameter means ± SD were Vc = 0.41 ± 0.18 L, Kcp = 2.80 ± 1.55/hour, Kpc = 1.71 ± 0.93/hour, and SCL = 0.16 ± 0.003 L/hour (r(2) = 0.99). The area under the plasma drug concentration - time curve for MFG1, MFG2, and MFG3 was 198.7 ± 19.8, 166.3 ± 36.7, and 192.8 ± 46.2 mg × hour/L, respectively (P = .24). All treatment groups showed significant and comparable resolution of (1→3)-β-D-glucan levels and clearance of C. albicans from liver, spleen, kidney, brain, lung, vitreous humor, and vena cava in comparison to untreated controls (P ≤ .05). There were no differences in hepatic or renal function among study groups. Less fractionated MFG regimens of every 48 and 72 hours are safe and as effective in experimental disseminated candidiasis as once-daily therapy in neutropenic hosts. © The Author 2015. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For Permissions, please e

  15. À Parte - Os Fundos de Pensão no Contexto da Financeirização Capitalista

    Directory of Open Access Journals (Sweden)

    Stefania Becattini Vaccaro

    2010-05-01

    Full Text Available <div>Este trabalho discute criticamente a expansão da previdência privadadiv>>fechada no Brasil. A premissa principal é de que se trata de um campo preferencialdiv>>de influência da esfera financeira que caracteriza a fase atual dodiv>>capitalismo. O objetivo é discutir a expansão do sistema de fundos de pensãodiv>>em substituição à previdência pública não como fator de aumento da proteçãodiv>>social, mas como condição para a conversão do dinheiro em capital quediv>>pode resultar numa catástrofe social. Para tanto, utiliza-se de método dedutivodiv>>de pesquisa, com base no aporte teórico desenvolvido por Hilferding (1985div>>dentro da dinâmica da relação social do capital. Os resultados evidenciamdiv>>que a escolha da previdência privada fechada é uma opção política dediv>>(imprevidência que pode trazer graves consequências sociais em razão dadiv>>volatilidade financeira dos investimentos a que se vinculam os fundos dediv>

    pensão.
    >Palavras-chave: Capital produtivo; previdência pública; fundos de pensão;div>>proteção social.div>

  16. Trabalho e Moradia na Periferia: para Uma Política Urbana Economicamente Orientada

    Directory of Open Access Journals (Sweden)

    Luciana Corrêa Lago

    2010-05-01

    Full Text Available <div>O artigo examina as conexões entre as mudanças no mundo dodiv>>trabalho e a qualidade de vida urbana na metrópole do Rio de Janeiro, buscandodiv>>estender os sentidos do conceito de trabalho precário utilizado emdiv>>análises estruturais de natureza estatística. A dimensão territorial, entendidadiv>>como os lugares e as distâncias na cidade é incorporada como fator determinantediv>>de bem-estar social e como expressão e instrumento de poder econômicodiv>>e simbólico. O texto conjuga uma leitura estrutural do mercado dediv>>trabalho metropolitano, privilegiando os municípios periféricos e os trabalhadoresdiv>>manuais, com a apreensão de algumas experiências de trabalho nodiv>>setor de confecção de roupas, em bairros operários na periferia. A principaldiv>>conclusão é de que a concentração territorial do setor de confecções e o saberdiv>>acumulado pelas costureiras como trabalhadoras autônomas são doisdiv>>elementos necessários para a ampliação de ações coletivas que disputem ediv>>redirecionem os recursos públicos para o fortalecimento de experiências autogestionáriasdiv>>de trabalho e para a reprodução do trabalhador e sua família.div>>Palavras-chave: Território; trabalho precário; trabalho doméstico; autogestão;div>>qualidade de vida urbana.div>

  17. A Política de Atenção Integral à Saúde do Adolescente e Jovem: uma perspectiva de garantia de direito à saúde?

    Directory of Open Access Journals (Sweden)

    Clarissa Raposo

    2010-05-01

    Full Text Available <div>o texto analisa a interface entre o paradigma dos direitos da infânciadiv>>e adolescência no Brasil (Estatuto da Criança e do Adolescente - ECA e adiv>>legislação do Sistema Único de Saúde (SUS. Destacando as diretrizes dediv>>municipalização/descentralização, o atendimento integral, a participação dadiv>>comunidade, e os princípios de universalidade, integralidade e igualdade,div>>situa a política de saúde do adolescente, identifica as suas diretrizes e osdiv>>eixos prioritários de ação e reflete sobre os seus delineamentos no contextodiv>>atual de precarização do financiamento, gestão e serviços do SUS. Relacionadiv>>as formas de violação do direito à saúde e a vulnerabilidade na adolescênciadiv>>como expressões contundentes de um contexto de transformações estruturaisdiv>>operadas sob a crise do capitalismo contemporâneo. Defende a perspectivadiv>>crítica e analítica marxiana para compreender a realidade contemporânea ediv>>desmistificar a concepção liberal de política social como direito de cidadania,div>>para que esta seja entendida como meio (e não como um fim para construçãodiv>>de uma sociedade igualitária.div>

  18. Relações Internacionais, Política Social e Combate à Pobreza

    Directory of Open Access Journals (Sweden)

    Ana Paula Ornellas Mauriel

    2010-05-01

    Full Text Available <div>o artigo objetiva demonstrar como as políticas sociais atuais vemdiv>>sendo definidas na arena internacional a partir da estrutura das relações internacionaisdiv>>e do contexto de globalização financeira. O combate à pobreza,div>>principal tendência da política social desde as reformas liberalizantes dosdiv>>anos 1980, aparece como estratégia central de manutenção do atual padrãodiv>>de acumulação, funcionando como instrumento de regulação dos custos dodiv>>trabalho no mercado mundial. Aspectos importantes das relações internacionaisdiv>>são destacados, onde os Estados aparecem como principais atoresdiv>>na construção de acordos e regulações internacionais garantidores de umdiv>>determinado tipo de desenvolvimento econômico e social via reformas liberalizantesdiv>>sob a égide da hegemonia norte-americana.div>

  19. A Survey for Assessment of Role of Pharmacist in Community

    Directory of Open Access Journals (Sweden)

    P Kapur

    2009-12-01

    Full Text Available <div>Objective: To assess the role of pharmacist in community setting & consumer’s perception in National Capitaldiv>

    Region.
    >Setting: The study was conducted in National Capital Region of India during the year 2003-04.div>>Method: Four pharmacy shops were selected for this study which were not attached to any hospital or clinic. Seventydiv>>seven consumers, who visited these pharmacies during the study period, were selected for this study anddiv>>interviewed just after they visited the pharmacy.div>>Key findings: A total of 77 consumers in the age group of 11 to 72 years were included in the present study, ofdiv>>which 66.2% were males and 33.8% were females. It is observed that 46.7% consumers came for prescriptiondiv>>medicines, 23.4% for over the counter medicines. Close to general physicians’ clinics and proximity to homediv>>were most important reasons given for visiting particular pharmacy. Majority of the consumers (n=56, 72.7%div>>rated the advice given by the pharmacist as very useful, only 1(1.3% rated it as not useful at all and 2 (2.6%div>>consumers did not respond. Among consumer groups 31 (40.3% thought that pharmacist has a good balancediv>>between health and business matter and 35.7% were in opinion that pharmacist is more concerned with makingdiv>>money, while 5.2% supported that the pharmacist is also interested in the health of his/her customers. The pharmacistsdiv>>were ranked at the top with 28(36.4% by the consumers and favoured pharmacy as the most convenientdiv>>place to get advice about staying healthy.div>>Conclusion: Most of the consumers in the present study were of the opinion that pharmacist is concerned with thediv>>health of the consumers, though he/she is also interested in making money. Many respondents were unawarediv>>about the difference between pharmacist and doctor, most of them consider

  20. Direito à Convivência Familiar de Crianças Abrigadas: o papel do Ministério Público

    Directory of Open Access Journals (Sweden)

    Lúcia Ferreira e Sávio Bittencourt

    2010-05-01

    Full Text Available <div>Partindo dos estudos que demonstram que é na família estruturadadiv>>que crianças e adolescentes terão o seu desenvolvimento biopsicossocialdiv>>pleno, o artigo sugere a criação de políticas públicas que garantam o direitodiv>>à convivência familiar e comunitária de infantes abrigados, com programasdiv>>de apoio à família de origem. Defende a tese de que para cada criança oudiv>>adolescente abrigado deve ser instaurado um inquérito civil, presidido pelodiv>>Promotor de Justiça da Infância e da Juventude para investigar as causas dodiv>>abrigamento e as possibilidades de retorno à sua família biológica. Verificadadiv>>a impossibilidade deste retorno, em tempo curto e previsível, e esgotadas asdiv>>medidas de proteção que promovam o resgate dos vínculos familiaresdiv>>biológicos, o respeito ao mandamento constitucional obriga o Parquet àdiv>>adoção de medidas que levem à formação de novos vínculos familiares ediv>>comunitários, como a destituição do poder familiar e a colocação em famíliadiv>

    substituta.>

  1. Economia, Sociedade e Política na Construção de um Campo do Conhecimento: a Saúde Coletiva no Brasil

    Directory of Open Access Journals (Sweden)

    Silvia Gerschman

    2010-05-01

    Full Text Available <div>O objetivo do texto é mostrar que “Saúde Coletiva” constitui umdiv>>novo campo de saber situado na interseção de vários saberes e práticas.div>>Ressalta a contribuição específica da ciência política na conformação dessadiv>>nova “disciplina” acompanhando algumas vertentes fundadoras dodiv>>pensamento político até a emergência das funções sociais do Estado. A autoradiv>>chama atenção para a insuficiência da reflexão sobre Saúde Coletiva comodiv>>política social quando se limita a discutir os aspectos operacionais de suadiv>>gestão, avaliação e controle sugerindo que se privilegie o exame da naturezadiv>>do Estado que condiciona, amplia ou encolhe os limites e natureza dasdiv>>políticas sociais. Conclui afirmando a necessidade de uma formaçãodiv>>disciplinar específica apoiada em disciplinas que tragam densidade teórica ediv>>analítica ao campo de conhecimento “Saúde Coletiva” como política social.div>

  2. Algunos aspectos del espectro Autista. Un trastorno inusitadamente frecuente y doloroso.

    Directory of Open Access Journals (Sweden)

    Daniel Jácome Roca

    2008-07-01

    Full Text Available <div data-canvas-width="403.526025">El autismo (o espectro autista es un desorden neuro-conductual –hereditario y heterogéneo-div> data-canvas-width="333.2950000000001">del desarrollo del cerebro, que comienza en niños menores de tres años de edad y que deterioradiv> data-canvas-width="389.2716666666667">su comunicación e interacción social causando un comportamiento restringido y repetitivo. Pueden jugardiv> data-canvas-width="382.6300000000001">un papel en estos síndromes, algunas anormalidades cromosómicas. Las soluciones ni son simples nidiv> data-canvas-width="387.275">uniformes en los diferentes síndromes, que algunas veces se asocian con patologías conocidas como eldiv> data-canvas-width="386.0416666666668">síndrome de Down, rubéola congénita, síndromes de Rett o de la X frágil, embriopatía por valproato, etc.div>

     
    >Para hacer un diagnóstico de autismo, el DSM-IV –de la Asociación Americana de Psiquiatría- indica que es necesario encontrar las siguientes características:div> data-canvas-width="388.15999999999997">A. Un total de seis o más manifestaciones de (1, (2 y (3, con l menos dos de (1, al menos unadiv> data-canvas-width="223.25000000000006">de (2, y al menos una de (3.div> data-canvas-width="389.145">1. Trastorno cualitativo de la relación, expresado como mínimo en dos de las siguientes manifestaciones:div> data-canvas-width="388.4216666666668">a. Trastorno importante en muchas conductas de relación no verbal, como la mirada a los ojos, ladiv> data-canvas-width="356.5000000000001">expresión facial, las posturas corporales y los gestos para regular la interacción social.div> data-canvas-width="389.7833333333333">b. Incapacidad para desarrollar relaciones con iguales adecuadas al nivel de desarrollo.div> data-canvas-width="382.6183333333334">c. Ausencia de conductas espontáneas encaminadas a compartir placeres

  3. Intellectual property-A strong determinant of Economic Growth

    Directory of Open Access Journals (Sweden)

    Love k Singh

    2009-12-01

    Full Text Available <div>The returns from almost all human endeavors can ultimately be translated into monetary gains. The past few yearsdiv>>have seen increased attention to the strengthening of intellectual property rights due to globalization. The developmentdiv>>of Intellectual property rights (IPR over the years has invariably brought an upsurge in the outlook ofdiv>>nations towards the aspect of societal and cultural growth, this being said with the preliminary assumption thatdiv>>economic growth has been the most affected realm and that it requires a separate spectrum of analysis. The artifactsdiv>>between the IP regime and the national economy can be easily interpreted by the fact that India’s independencediv>>had itself brought an era where the enactment of the national IP laws were considered to stand on the touchstonediv>>of the market economy. The aim of the present paper is to investigate the impact of strong IP regime in thediv>>economic development of a nation and also a light is raised into Indian economy and creation for an efficientdiv>>innovating system is discussed. A strong relation of IPR wity pharma sector and biotech sector has been discussed.div>>Undoubtedly, IP systems must be developed so as to bring in socio-economic well-being. The fact thatdiv>>strong IPR actually provoke IPR infringements in many developing nations also seems to be an issue which needsdiv>>to be analyzed while understanding the need of the former. The trade-off between unfair competition laws and IPdiv>>also assumes importance of high magnitude and hence needs to be particularly emphasized. With the growingdiv>>recognition of IPR, the importance of world wide forums on IPR is realized. Companies, universities, and industriesdiv>>want to protect their IPR internationally. In order to reach this goal, countries have signed numerous agreementsdiv>>and treaties.div>

  4. Analgesic Effects of Various Extracts of Root of Abutilon indicum linn.

    Directory of Open Access Journals (Sweden)

    Sumitra Singh

    2009-12-01

    Full Text Available <div>Abutilon indicum (Linn. sweet (Malvaceae commonly called “Country Mallow” is a perennial plant up to 3m indiv>>height. It is abundantly found as weed in sub-Himalayan tract and in hotter parts of India. The plant is traditionallydiv>>used for treatment of several diseases like bronchitis, body ache, toothache, jaundice, diabetes, fever, piles,div>>leprosy, ulcers, cystitis, gonorrhea, diarrhoea etc. Abutilon indicum Linn. is reported to have hepatoprotective,div>>hypoglycemic, antimicrobial, male contraceptive and antidiarrhoeal activities. The present study was done todiv>>evaluate the analgesic potential of various extracts of root of Abutilon indicum Linn. The powdered root (900 gdiv>>was subjected to successive solvent extraction with solvents in increasing order of polarity viz. petroleum etherdiv>>(60-80 C°, methanol and ethanol by soxhlet apparatus for 72 hrs. The marc was extracted by cold maceration fordiv>>72 hrs. to obtain water soluble extract. Peripheral analgesic activity was studied using acetic acid induced writhingdiv>>method in Swiss albino mice (20-30 g while central analgesic activity was evaluated by tail flick method anddiv>>tail immersion method. Results indicated that all the tested extracts except methanol extract exhibited significantdiv>>analgesic activity in both animals’ models. Petroleum ether extract showed higher analgesic activity. The activitydiv>>may be related with central mechanism or due to peripheral analgesic mechanisms. Thus the present study authenticatesdiv>>the traditional use.div>

  5. Para uma Crítica Marxista do Estado e da Administração Pública

    Directory of Open Access Journals (Sweden)

    Andrêssa Gomes Carvalho de Amorim

    2010-05-01

    Full Text Available <div>o texto aborda a natureza essencial do Estado visando compreenderdiv>>a administração pública e os princípios básicos da organização administrativadiv>>(a justiça e a eficiência como partes complementares e essenciais para adiv>>permanente reprodução do sistema do capital. O ensaio está estruturado emdiv>>três itens, sendo que o primeiro aborda a natureza do Estado e a função dadiv>>administração pública, seguindo-se de uma reflexão sobre a cidadania e adiv>>burocracia estatal enquanto mecanismos de mistificação da exploração ediv>>dominação de classe na sociedade capitalista. Por fim, o artigo enfatiza quediv>>o Estado e a ação política têm limites bem definidos no campo objetivo,div>>intransponíveis e imanentes à dominação social pela sua funcionalidade aodiv>>capitalismo, sendo esta, portanto, seu ineliminável sentido social.div>

  6. A História do Serviço Social Pensada a Partir da “Revista do Padre Saboia” – Revista de Serviço Social – São Paulo

    Directory of Open Access Journals (Sweden)

    Camila Manduca Ferreira

    2010-05-01

    Full Text Available <div>O artigo resulta de pesquisa sobre a primeira revista de Serviço Socialdiv>>do Brasil (1939-56, publicada pela Escola de Serviço Social de São Paulo,div>>primeira unidade de ensino do país (1936. Envolvendo os primeiros assistentesdiv>>sociais mais engajados na Ação Católica e figuras eminentes do período nodiv>>corpo de editores e colaboradores, a Revista Serviço Social alcançou notoriedadediv>>sob a direção do padre Roberto Saboia de Medeiros, passando a serdiv>>comumente conhecida como “revista do padre Saboia”. A metodologia privilegioudiv>>a análise temática dos artigos publicados. A conclusão enfatiza o tratamentodiv>>conservador dado à relação capital/trabalho, à pobreza, à formaçãodiv>>profissional, ao trabalho do assistente social, às relações com o Estado e asdiv>>visões do país. O estudo mostra também que a Revista Serviço Social é fontediv>>primária privilegiada para o estudo da gênese do Serviço Social no Brasil.div>>Palavras-chave: Revista Serviço Social; história do Serviço Social; Serviço Social.div>

  7. Dependencia Estructural en los mercados Bursátiles de Colombia y Estados Unidos, una aproximación usando cópulas

    Directory of Open Access Journals (Sweden)

    Cardona Salgado Daiver

    2012-11-01

    Full Text Available <div>Para determinar la dependencia estructural entre los mercados bursátiles colombiano y div>>estadounidense, se usaron las pérdidas de los índices Col20, Dow Jones y Standard & div>>Poors 500 como variables. La metodología desarrollada siguió los lineamientos de los div>>modelos de dinámica multivariados, basados en la cópula y propuestos por Chen y Fan div>>(2006. Se encontró que los dos mercados presentan una moderada dependencia y que, div>>de acuerdo con el modelo CAPM, el riesgodiv>>sistemático que comparten es bajo y ofrecen posibilidades de diversificación. Además, se div>>encontró que es baja la probabilidad de que ambos mercados experimenten pérdidas div>>extremas conjuntamente.div>

  8. À PARTE - Pensamento Autoritário e Modernidade no Brasil

    Directory of Open Access Journals (Sweden)

    Silene de Moraes Freire

    2010-05-01

    Full Text Available <div>O presente artigo analisa a vinculação do pensamento autoritário aodiv>>projeto político do capital industrial no Brasil entre os anos 1930 e 1940, pordiv>>meio de estudo de trabalhos representativos da época e de outras pesquisas ediv>>ensaios sobre o tema. A conclusão central é sobre a forma instrumental dessediv>>pensamento político para a legitimação de uma modernização de tipo conservadoradiv>>caminho da modernização capitalista brasileira.div>>Palavras-chave: Pensamento Político Autoritário; Brasil; Revolução Burguesa.div>

  9. Multiple Family Group Service Model for Children With Disruptive Behavior Disorders: Child Outcomes at Post-Treatment.

    Science.gov (United States)

    Chacko, Anil; Gopalan, Geetha; Franco, Lydia; Dean-Assael, Kara; Jackson, Jerrold; Marcus, Sue; Hoagwood, Kimberly; McKay, Mary

    2015-06-01

    The purpose of this study was to determine the benefits of a multiple family group (MFG) service delivery model compared with services as usual (SAU) in improving the functioning of youth with oppositional defiant/conduct disorder in families residing in socioeconomically disadvantaged communities. Participants included 320 youth aged 7 to 11 and their families who were referred to participating outpatient clinics. Participants were assigned to the MFG or the SAU condition, with parent report of child oppositional behavior, social competence, and level of youth impairment as primary outcomes at post-treatment. Family engagement to MFG was measured by attendance to each group session. Caregivers of youth in the MFG service delivery model condition reported significant improvement in youth oppositional behavior and social competence compared with youth in the SAU condition. Impairment improved over time for both groups with no difference between treatment conditions. The MFG led to greater percentage of youth with clinically significant improvements in oppositional behavior. Attendance to the MFG was high, given the high-risk nature of the study population. The MFG service delivery model offers an efficient and engaging format to implement evidence-based approaches to improving functioning of youth with oppositional defiant and/or conduct disorder in families from socioeconomically disadvantaged communities.

  10. Novelty Seeking, Harm Avoidance, and Cerebral Responses to Conflict Anticipation: An Exploratory Study.

    Science.gov (United States)

    Hu, Jianping; Hu, Sien; Maisano, Julianna R; Chao, Herta H; Zhang, Sheng; Li, Chiang-Shan R

    2016-01-01

    Proactive control allows us to maneuver a changing environment and individuals are distinct in how they anticipate and approach such changes. Here, we examined how individual differences in personality traits influence cerebral responses to conflict anticipation, a critical process of proactive control. We explored this issue in an fMRI study of the stop signal task, in which the probability of stop signal - p(Stop) - was computed trial by trial with a Bayesian model. Higher p(Stop) is associated with prolonged go trial reaction time, indicating conflict anticipation and proactive control of motor response. Regional brain activations to conflict anticipation were correlated to novelty seeking (NS), harm avoidance (HA), reward dependence, as assessed by the Tridimensional Personality Questionnaire, with age and gender as covariates, in a whole-brain linear regression. Results showed that increased anticipation of the stop signal is associated with activations in the bilateral inferior parietal lobules (IPL), right lateral orbitofrontal cortex (lOFC), middle frontal gyrus (MFG), anterior pre-supplementary motor area (pre-SMA), and bilateral thalamus, with men showing greater activation in the IPL than women. NS correlated negatively to activity in the anterior pre-SMA, right IPL, and MFG/lOFC, and HA correlated negatively to activity in the thalamus during conflict anticipation. In addition, the negative association between NS and MFG/lOFC activity was significant in men but not in women. Thus, NS and HA traits are associated with reduced mobilization of cognitive control circuits when enhanced behavioral control is necessary. The findings from this exploratory study characterize the influence of NS and HA on proactive control and provide preliminary evidence for gender differences in these associations.

  11. Sincronización de los Ciclos Económicos: el Caso de Colombia, Ecuador y Venezuela

    Directory of Open Access Journals (Sweden)

    Salamanca Lugo Andrés

    2012-11-01

    Full Text Available <div>En este documento se investiga acerca de la existencia y la identificación de un ciclo div>>económico común entre Colombia, Ecuador y Venezuela. Se busca una evidencia de ladiv>>sincronización de los ciclos económicos de estos países, a través de diferentes medidas div>>no paramétricas, en conformidad con los ciclos y mediante la construcción de un ciclo div>>común de referencia. De acuerdo con esto, se ajusta un modelo de Markov-Switchingdiv>>autoregresivo multivariado (MS-VAR que confirma la existencia de dicho ciclo. div>>Finalmente, la cronología del ciclo común es reconstruida a partir de las probabilidades div>>suavizadas del modelo y es contrastada con el ciclo común de referencia.div>

  12. Molecular Modelling

    Directory of Open Access Journals (Sweden)

    Aarti Sharma

    2009-12-01

    Full Text Available <div>The use of computational chemistry in the development of novel pharmaceuticals is becoming an increasingly importantdiv>>tool. In the past, drugs were simply screened for effectiveness. The recent advances in computing power anddiv>>the exponential growth of the knowledge of protein structures have made it possible for organic compounds to tailored todiv>>decrease harmful side effects and increase the potency. This article provides a detailed description of the techniquesdiv>>employed in molecular modeling. Molecular modelling is a rapidly developing discipline, and has been supported fromdiv>>the dramatic improvements in computer hardware and software in recent years.div>

  13. RESENHA - Para pensar sobre o Mundo del Trabajo y los Caminos de la Vida

    Directory of Open Access Journals (Sweden)

    Norberto Alayón

    2010-05-01

    Full Text Available <div>El mundo del trabajo y los caminos de la vida.div>>Trabajar para vivir; vivir para trabajar - Estela Grassi y Claudiadiv>>Danani (organizadoras Espacio Editorial (Colección “Desarrollodiv>>Social y Sociedad”. Buenos Aires. 2009. 374 páginas.div>

  14. Estado actual de la cirugia general laparoscópica Present state of videolaparascopic surgery

    Directory of Open Access Journals (Sweden)

    Carlos Hernándo Morales Uribe

    1994-04-01

    Full Text Available <div>Los procedimientos laparoscópicos han empezado a reemplazar algunas operacionesdiv>>convencionales porque evitan la cirugía mayor y se logra una recuperación precoz del paciente. En el futuro muchas cirugías tradicionales se realizarán laparoscópicamente. En este artículo se presenta el estado actual de la cirugía laparoscópica en los siguientes casos: cirugía biliar, úlcera péptica, corrección del reflujo gastroesofágicodiv>>y de algunos trastornos motores esofágicos, abdomen agudo, herniorrafia inguinaldiv>>y cirugía colorrectal. Se consignan las ventajas y desventajas en general y para cadadiv>>caso en particular.div> <div>Laparascopic pracedures have begun to replace the conventional ones in arder todiv>>avoid major surgery and to allow an earlier recovery of the patlent. In thls article thediv>>present state of laparoscopic surgery is revlewed, concernlng the followlng entities:div>>blliary surgery, peptlc ulcer, correction of gastroesophageal reflux and of esophagealdiv>>motility problems, acute abdomen, ingulnal herniorrhaphy and colorectal surgery. Advantages and dlsadvantages are consldered both in general and for each speclflc case. div>

  15. The BRICs in the Global Value Chains: An Empirical Note

    Directory of Open Access Journals (Sweden)

    Chen Lurong

    2012-11-01

    Full Text Available <div>Este artículo explora las interconexiones entre las economías BRIC y la economíadiv>>mundial a través del análisis de sus competitividades y desventajas claves en las cadenas div>>globales de valor agregado. Además, muestra que las economías BRIC continúan en los div>>fragmentos de menor valor de las cadenas globales de valor agregado. A largo plazo, su div>>crecimiento económico podría estar limitado por la capacidad tecnológica. Por lo tanto, div>>para que los BRIC puedan sostener su desarrollo en el largo plazo, deben enfocarse en div>>mejorar su capacidad tecnológica para ascender en las cadenas de valordiv>

  16. A Survey for Assessment of Role of Pharmacist in Community

    OpenAIRE

    P Kapur; M Aqil; M S Alam; S Karim; Himanshu Sharma; P Jinda

    2009-01-01

    <div>Objective: To assess the role of pharmacist in community setting & consumer’s perception in National Capitaldiv>

    Region.
    >Setting: The study was conducted in National Capital Region of India during the year 2003-04.div>>Method: Four pharmacy shops were selected for this study which were not attached to any hospital or clinic. Seventydiv>>seven consumers, who visited these pharmacies during ...

  17. Interferencia de la infección por rotavirus mediante la inhibición de la actividad de la proteína disulfuro isomerasa (DPI de la membrana celular de las líneas MA104 y Caco-2.

    Directory of Open Access Journals (Sweden)

    Carlos Arturo Guerrero Fonseca

    2008-12-01

    Full Text Available <div>Los rotavirus son la causa más común de gastroenteritis severa en niños menores de cinco años, ocasionando episodios diarreicos agudos responsables de 454.000 a 705.000 muertes anuales a nivel mundial.div>

     
    >Aunque la frecuencia de infección con rotavirus es muy similar a través del mundo, en los países en desarrollo la gastroenteritis rotaviral es la mayor causa de muerte infantil. div> data-canvas-width="19.169999999999998"> div> data-canvas-width="16.68">La diarrea rotaviral severa cursa con vómito y fiebre, produciendo deshidratación con shock, desbalance electrolítico, y muerte si esta no es tratada. En los países desarrollados, la infección rotaviral es responsable del 30 - 50% de las hospitalizaciones debidas a gastroenteritis en menores de 5 años. div> data-canvas-width="16.68">Además, los rotavirus son una causa importante en la gastroenteritis nosocomial.div> data-canvas-width="46.68"> div> data-canvas-width="28.35"> div> data-canvas-width="18.345000000000002"> div>

  18. Functional Role of Milk Fat Globule-Epidermal Growth Factor VIII in Macrophage-Mediated Inflammatory Responses and Inflammatory/Autoimmune Diseases

    Directory of Open Access Journals (Sweden)

    Young-Su Yi

    2016-01-01

    Full Text Available Inflammation involves a series of complex biological processes mediated by innate immunity for host defense against pathogen infection. Chronic inflammation is considered to be one of the major causes of serious diseases, including a number of autoimmune/inflammatory diseases, cancers, cardiovascular diseases, and neurological diseases. Milk fat globule-epidermal growth factor 8 (MFG-E8 is a secreted protein found in vertebrates and was initially discovered as a critical component of the milk fat globule. Previously, a number of studies have reported that MFG-E8 contributes to various biological functions including the phagocytic removal of damaged and apoptotic cells from tissues, the induction of VEGF-mediated neovascularization, the maintenance of intestinal epithelial homeostasis, and the promotion of mucosal healing. Recently, emerging studies have reported that MFG-E8 plays a role in inflammatory responses and inflammatory/autoimmune diseases. This review describes the characteristics of MFG-E8-mediated signaling pathways, summarizes recent findings supporting the roles of MFG-E8 in inflammatory responses and inflammatory/autoimmune diseases, and discusses MFG-E8 targeting as a potential therapeutic strategy for the development of anti-inflammatory/autoimmune disease drugs.

  19. Functional MRI Study of Working Memory Impairment in Patients with Symptomatic Carotid Artery Disease

    Directory of Open Access Journals (Sweden)

    Shasha Zheng

    2014-01-01

    Full Text Available The neuropsychological tests in patients with internal carotid artery (ICA demonstrated cognitive deficits associated with frontal lobe dysfunction, but the pathophysiological mechanism of memory impairment is not fully understood. This study evaluated relationship between degree of ICA stenosis and frontal activations induced by working memory (WM task using fMRI. The fMRI data of 21 patients with unilateral ICA stenosis (left/right, 11/10 and 21 controls were analyzed. In comparison with controls, ICA patients demonstrated significant activations in middle frontal gyrus (MFG bilaterally, particularly in left MFG. In right ICA stenosis, there was slightly less MFG activation than that of controls. Importantly, lower MFG activity was associated with higher stenosis of ipsilateral ICA. For left ICA stenosis, weaker activation in left MFG was negatively correlated with degree of stenosis. Similarly, for right ICA stenosis, there was a significant negative correlation between right ICA stenosis and weaker activation of right MFG. Cognitive impairments in ICA stenosis were associated with frontal lobe dysfunctions. Left ICA stenosis had worse WM impairments than right ICA stenosis, which was affected by the degree of stenosis.

  20. Pharmacokinetic study and interaction with the reticulo-endothelial system of a plasma substitute: modified fluid gelatine

    International Nuclear Information System (INIS)

    Vie, M.-T.

    1973-01-01

    By the labelling of a plasma substitute prepared from gelatine, MFG or modified fluid gelatine, it was possible to establish certain facts concerning the kinetics of MFG and its action on the cells of the reticulo-endothelial system. Iodine labelling proved sufficiently reliable to allow the pharmakokinetic exploration of the product by a method which, being relatively simple to use, offers good reproducibility of results. Various tests on the strength of the iodine protein bond showed the stability of the entire protein molecule. A study of the metabolism revealed that the MFG in question behaves towards the organism not as a pure substance but as a mixture of two molecular species of different mass. The experimental results concerning the influence of MFG on the reticulo-endothelial system showed that the phagocyte function is only modified if there is competition between the phagocyted molecule and the MFG [fr

  1. Papel dos avós: apoio oferecido aos netos antes e após situações de separação/divórcio dos pais The grandparents role: support offered to the grandchildren before and after situations of parent's separation/divorce

    Directory of Open Access Journals (Sweden)

    Mayeve Rochane Gerônimo Leite Araújo

    2002-01-01

    Full Text Available A presente pesquisa teve como objetivo averiguar os tipos de apoio oferecidos pelos avós aos netos antes e após situações de separação/divórcio dos pais, bem como a existência ou não de alterações nas formas de apoio. Foram considerados dois tipos de apoio: o emocional e o instrumental, sob a influência das seguintes variáveis: distância geográfica, custódia parental, vinculação materna ou paterna, idade, situação empregatícia e estado civil dos avós. Participaram da mesma 30 avós que não moravam com os netos, antes nem após a separação/divórcio dos pais. O instrumento utilizado foi um questionário contendo itens que atendiam aos objetivos da pesquisa, bem como os dados sócio-demográficos. Os resultados indicaram uma preferência, por parte dos avós, pelas atividades do tipo emocional, notando-se um aumento, em geral, após a separação/divórcio, nas seguintes atividades: dar conselhos, transmitir informações sobre a família, telefonar e uma diminuição na atividade visitar.The present research aimed to discover the types of support offered by the grandparents to grandchildren, before and after the parents' separation/divorce, as well as the possible changes in the forms of support. Two types of support were analyzed: the emotional and the instrumental, considering the influence of the following variables: geographical distance, custody, maternal or paternal link, age, marital status and grandparents' job situation. The subjects were 30 grandparents who didn't live with their grandchildren, before or after the parent's separation/divorce, were selected. The instrument used was a questionnaire with items which met the objectives of the research. The social demographic factors were also considered. Results indicated a preference for activities of the emotional type, with a general increase, after the separation/divorce, in activities such as: giving advice, transmitting information concerning the family, and

  2. MAMMARY SOLID CARCINOMA WITH SPINAL CORD METASTASIS CARCINOMA SÓLIDO DE GLÂNDULA MAMÁRIA COM METÁSTASE EM MEDULA ESPINHAL

    Directory of Open Access Journals (Sweden)

    Denise Caroline Toledo

    2009-12-01

    Full Text Available <div>Mammary neoplasias are common in canine females and carcinomas, among malignant types, occur frequently, especially solid form. At gross view, it can be small and incipient, but it’s invasive and show little differentiation, being able to produce metastasis that can compromise animal survive. This describes a bitch, Fila Brasileiro, six year old with tetraplegy and cervical spinal cord metastasis of mammary solid carcinoma.div>>
    div>>KEYWORDS: Central nervous system, dog, mammary neoplasia.div>>
    div> <div>Neoplasias mamárias são comuns entre as fêmeas caninas e os carcinomas, dentre as formas malignas, ocorrem com maior frequência, particularmente o tipo sólido. Estes podem apresentar-se pequenos e incipientes à macroscopia, contudo são invasivos e pouco diferenciados, com possibilidade de produzir metástases que comprometem a sobrevida do animal. Assim, descreve-se o caso de uma cadela, da raça Fila Brasileiro, de seis anos, que apresentou tetraplegia consequente à metástase medular cervical de carcinoma sólido mamário.div>>
    div>>PALAVRAS-CHAVES: Cão, neoplasia mamária, sistema nervoso central.div>>
    div>

  3. Expediente

    Directory of Open Access Journals (Sweden)

    Editor de Seção Em Pauta

    2010-05-01

    Full Text Available <div>Teoria Social e Realidade Contemporânea é um periódico semestral, arbitrado, de circulação nacional e internacional,div>>dirigido a assistentes sociais e profissionais de áreas afins, professores, pesquisadores e demais sujeitos políticos,div>>comprometidos com os processos democráticos.div>>A revista pretende ser um instrumento de divulgação e de disseminação de produções atuais e relevantes do ensino, dadiv>>pesquisa e extensão, no âmbito do Serviço Social e de áreas afins, através da publicação de artigos, ensaios teóricos, pesquisasdiv>>científicas, resenhas de livro, comunicações, relatórios de pesquisas científicas e informes, visando contribuir para a formulaçãodiv>>e a divulgação de políticas públicas e debates, no âmbito da academia e da sociedade civil.div>

  4. Degree of facial and body terminal hair growth in unselected black and white women: toward a populational definition of hirsutism.

    Science.gov (United States)

    DeUgarte, Catherine Marin; Woods, K S; Bartolucci, Alfred A; Azziz, Ricardo

    2006-04-01

    Hirsutism (i.e. facial and body terminal hair growth in a male-like pattern in women) is the principal clinical sign of hyperandrogenism, although its definition remains unclear. The purposes of the present study were to define 1) the degree of facial and body terminal hair, as assessed by the modified Ferriman-Gallwey (mFG) score, in unselected women from the general population; 2) the effect of race (Black and White) on the same; and 3) the normative cutoff values. We conducted a prospective observational study at a tertiary academic medical center. Participants included 633 unselected White (n = 283) and Black (n = 350) women presenting for a preemployment physical exam. Interventions included history and physical examination. Terminal body hair growth was assessed using the mFG scoring system; nine body areas were scored from 0-4 for terminal hair growth distribution. The mFG scores were not normally distributed; although cluster analysis failed to identify a natural cutoff value or clustering of the population, principal component and univariate analyses denoted two nearly distinct clusters that occurred above and below an mFG value of 2, with the bulk of the scores below. Overall, an mFG score of at least 3 was observed in 22.1% of all subjects (i.e. the upper quartile); of these subjects, 69.3% complained of being hirsute, compared with 15.8% of women with an mFG score below this value, and similar to the proportion of women with an mFG score of at least 8 who considered themselves to be hirsute (70.0%). Overall, there were no significant differences between Black and White women. Our data indicate that the prevalence and degree of facial and body terminal hair growth, as assessed by the mFG score, is similar in Black and White women and that an mFG of at least 3 signals the population of women whose hair growth falls out of the norm.

  5. Using mobile health technology to improve behavioral skill implementation through homework in evidence-based parenting intervention for disruptive behavior disorders in youth: study protocol for intervention development and evaluation.

    Science.gov (United States)

    Chacko, Anil; Isham, Andrew; Cleek, Andrew F; McKay, Mary M

    2016-01-01

    Disruptive behavior disorders (DBDs) (oppositional defiant disorder (ODD) and conduct disorder (CD)) are prevalent, costly, and oftentimes chronic psychiatric disorders of childhood. Evidence-based interventions that focus on assisting parents to utilize effective skills to modify children's problematic behaviors are first-line interventions for the treatment of DBDs. Although efficacious, the effects of these interventions are often attenuated by poor implementation of the skills learned during treatment by parents, often referred to as between-session homework. The multiple family group (MFG) model is an evidence-based, skills-based intervention model for the treatment of DBDs in school-age youth residing in urban, socio-economically disadvantaged communities. While data suggest benefits of MFG on DBD behaviors, similar to other skill-based interventions, the effects of MFG are mitigated by the poor homework implementation, despite considerable efforts to support parents in homework implementation. This paper focuses on the study protocol for the development and preliminary evaluation of a theory-based, smartphone mobile health (mHealth) application (My MFG) to support homework implementation by parents participating in MFG. This paper describes a study design proposal that begins with a theoretical model, uses iterative design processes to develop My MFG to support homework implementation in MFG through a series of pilot studies, and a small-scale pilot randomised controlled trial to determine if the intervention can demonstrate change (preliminary efficacy) of My MFG in outpatient mental health settings in socioeconomically disadvantaged communities. This preliminary study aims to understand the implementation of mHealth methods to improve the effectiveness of evidence-based interventions in routine outpatient mental health care settings for youth with disruptive behavior and their families. Developing methods to augment the benefits of evidence

  6. Structure organization and magnetic properties of microscale ferrogels: The effect of particle magnetic anisotropy

    Science.gov (United States)

    Ryzhkov, Aleksandr V.; Melenev, Petr V.; Balasoiu, Maria; Raikher, Yuriy L.

    2016-08-01

    The equilibrium structure and magnetic properties of a ferrogel object of small size (microferrogel(MFG)) are investigated by coarse-grained molecular dynamics. As a generic model of a microferrogel (MFG), a sample with a lattice-like mesh is taken. The solid phase of the MFG consists of magnetic (e.g., ferrite) nanoparticles which are mechanically linked to the mesh making some part of its nodes. Unlike previous models, the finite uniaxial magnetic anisotropy of the particles, as it is the case for real ferrogels, is taken into account. For comparison, two types of MFGs are considered: MFG-1, which dwells in virtually non-aggregated state independently of the presence of an external magnetic field, and MFG-2, which displays aggregation yet under zero field. The structure states of the samples are analyzed with the aid of angle-resolved radial distribution functions and cluster counts. The results reveal the crucial role of the matrix elasticity on the structure organization as well as on magnetization of both MFGs. The particle anisotropy, which plays insignificant role in MFG-1 (moderate interparticle magnetodipole interaction), becomes an important factor in MFG-2 (strong interaction). There, the restrictions imposed on the particle angular freedom by the elastic matrix result in notable diminution of the particle chain lengths as well as the magnetization of the sample. The approach proposed enables one to investigate a large variety of MFGs, including those of capsule type and to purposefully choose the combination of their magnetoelastic parameters.

  7. Gradient-Type Magnetoelectric Current Sensor with Strong Multisource Noise Suppression.

    Science.gov (United States)

    Zhang, Mingji; Or, Siu Wing

    2018-02-14

    A novel gradient-type magnetoelectric (ME) current sensor operating in magnetic field gradient (MFG) detection and conversion mode is developed based on a pair of ME composites that have a back-to-back capacitor configuration under a baseline separation and a magnetic biasing in an electrically-shielded and mechanically-enclosed housing. The physics behind the current sensing process is the product effect of the current-induced MFG effect associated with vortex magnetic fields of current-carrying cables (i.e., MFG detection) and the MFG-induced ME effect in the ME composite pair (i.e., MFG conversion). The sensor output voltage is directly obtained from the gradient ME voltage of the ME composite pair and is calibrated against cable current to give the current sensitivity. The current sensing performance of the sensor is evaluated, both theoretically and experimentally, under multisource noises of electric fields, magnetic fields, vibrations, and thermals. The sensor combines the merits of small nonlinearity in the current-induced MFG effect with those of high sensitivity and high common-mode noise rejection rate in the MFG-induced ME effect to achieve a high current sensitivity of 0.65-12.55 mV/A in the frequency range of 10 Hz-170 kHz, a small input-output nonlinearity of <500 ppm, a small thermal drift of <0.2%/℃ in the current range of 0-20 A, and a high common-mode noise rejection rate of 17-28 dB from multisource noises.

  8. Ideological Configurations and Prediction of Attitudes toward Immigrants in Chile and Germany

    Directory of Open Access Journals (Sweden)

    Héctor Carvacho

    2010-12-01

    Full Text Available <div>The concept of ideological configuration is proposed to refer to a complex of ideological attitudes – Right-Wing Authoritarianism (RWA and Social Dominancediv>>Orientation (SDO – based on a shared core of derogation of outgroups. This concept is used in two surveys, in Chile and in Germany, to predictdiv>>attitudes toward foreigners. Analyses using structural equation modeling (SEM showed that a second-order factor involving RWA and SDO predicts hostilitydiv>>toward foreigners in Germany and affection toward Peruvian and Argentinean immigrants in Chile. This prediction was stronger in Germany than in Chile.div>>The difference in strength is discussed in terms of the kind of measurements, different contexts of migration, and characteristics of the immigrants. Furtherdiv>>research using the concept of ideological configuration is proposed.div>

  9. Personālā datora sistēmas bloka vides snieguma novērtējums un ekodizaina analīze

    OpenAIRE

    Šteina, Māra

    2009-01-01

    Maģistra darba „Personālā datora sistēmas bloka vides snieguma novērtējums un ekodizaina analīze” pamatā ir biroja datora sistēmas bloka ietekmes uz vidi novērtējums visā tā dzīves cikla laikā, izvērtējot arī lietotāju un iesaistīto pušu nozīmi. Darbs sastāv no divām daļām – teorētiskās un praktiskās. Pirmā daļa ir teorētiskajā daļa, kurā autore apskatīja pieejamos literatūras avotus un citu autoru darbus, izvērtējot tēmas aktualitāti, galvenās problēmas un to risinājumus. Otrā daļa ...

  10. Gradient-Type Magnetoelectric Current Sensor with Strong Multisource Noise Suppression

    Science.gov (United States)

    2018-01-01

    A novel gradient-type magnetoelectric (ME) current sensor operating in magnetic field gradient (MFG) detection and conversion mode is developed based on a pair of ME composites that have a back-to-back capacitor configuration under a baseline separation and a magnetic biasing in an electrically-shielded and mechanically-enclosed housing. The physics behind the current sensing process is the product effect of the current-induced MFG effect associated with vortex magnetic fields of current-carrying cables (i.e., MFG detection) and the MFG-induced ME effect in the ME composite pair (i.e., MFG conversion). The sensor output voltage is directly obtained from the gradient ME voltage of the ME composite pair and is calibrated against cable current to give the current sensitivity. The current sensing performance of the sensor is evaluated, both theoretically and experimentally, under multisource noises of electric fields, magnetic fields, vibrations, and thermals. The sensor combines the merits of small nonlinearity in the current-induced MFG effect with those of high sensitivity and high common-mode noise rejection rate in the MFG-induced ME effect to achieve a high current sensitivity of 0.65–12.55 mV/A in the frequency range of 10 Hz–170 kHz, a small input-output nonlinearity of <500 ppm, a small thermal drift of <0.2%/℃ in the current range of 0–20 A, and a high common-mode noise rejection rate of 17–28 dB from multisource noises. PMID:29443920

  11. As bases eleitorais de Lula e do PT: do distanciamento ao divórcio

    Directory of Open Access Journals (Sweden)

    Sonia Luiza Terron

    2010-11-01

    Full Text Available O debate sobre o distanciamento entre Lula e o Partido dos Trabalhadores (PT ganhou corpo na eleição de 2006, quando a popularidade de Lula e de seu governo não se estendeu ao PT, como seria esperado. Pela primeira vez o partido não melhorou o desempenho na votação para a Câmara dos Deputados em relação à eleição anterior. Analisamos as bases eleitorais de Lula e do PT nas quatro últimas eleições para presidente e deputado federal (1994-2006, e comprovamos o distanciamento entre elas. Pesquisamos a distribuição espacial das votações ao nível do município com mapas, estatísticas e regressões espaciais. Identificamos o "descolamento" dos territórios eleitorais do candidato e do partido a cada eleição, e as regressões espaciais mediram a crescente independência espaço-temporal das votações: os coeficientes baixaram de 0,85 em 1994, para 0,15 em 2006. Houve um processo de distanciamento geossocial, no período de 1994 a 2002, e um "divórcio" entre as bases eleitorais, em 2006, quando se formaram territórios de configurações praticamente irrelacionadas.The debate about the distancing between Lula and the Workers Party (PT gained acceptance in the 2006 election, when the popularity of Lula and his government did not extend to the PT, as expected. For the first time the party did not improve performance in the voting for the Chamber of Deputies regarding the previous election. We analyzed the electoral bases of Lula and the PT in the last four elections for president and federal deputies (1994-2006, and we prove the distancing between them. We studied the spatial distribution of votes at the municipal level with maps, statistics and spatial regression. We identified the detachment of the candidate's and party's electoral territories every election, and the regressions measured the growing spatial-temporal independence of the votings: the coefficient fell from 0.85 in 1994 to 0.15 in 2006. There was a process of

  12. Elevated serum milk fat globule-epidermal growth factor 8 levels in type 2 diabetic patients are suppressed by overweight or obese status.

    Science.gov (United States)

    Li, Yuanyuan; Ran, Wenzhuo; Zhang, Jiaqiang; Chen, Shi; Li, Yihang; Luo, Deng; Wang, Chen; Jia, Weiping

    2017-02-01

    Inflammation is the most important link between obesity and type 2 diabetes (T2D). Although milk fat globule-epidermal growth factor 8 (MFG-E8) is a key mediator in anti-inflammatory responses, its role in obesity and diabetes is not yet completely understood. We aimed to measure MFG-E8 serum levels and to explore the role of MFG-E8 in obesity and T2D. Fasting serum MFG-E8 levels were quantified by enzyme-linked immunosorbent assay for 168 individuals, whose oral glucose tolerance test was conducted, and levels of inflammatory factors, including tumor necrosis factor-α (TNF-α) and C-reactive protein, were measured. The participants were subdivided into 66 newly diagnosed T2D individuals, 44 impaired glucose tolerance (IGT) subjects and 58 healthy controls. Their characteristics were further classified as lean or nonlean for investigation. MFG-E8 levels were significantly higher in T2D subjects than in healthy controls (P = 0.028). Decreased levels of MFG-E8 were found in overweight or obese individuals, compared to those in lean subjects, in both the T2D and IGT groups (P obesity and T2D in the clinical setting. © 2017 IUBMB Life, 69(2):63-71, 2017. © 2017 International Union of Biochemistry and Molecular Biology.

  13. Centro de Referência das Lutas Políticas no Brasil (1964-1985 Memórias Reveladas -Prof. Dra. Inez Stampa

    Directory of Open Access Journals (Sweden)

    Marilda Villela Iamamoto

    2012-04-01

    Full Text Available <div>A entrevista com a Prof. Dra. Inez Terezinha Stampadiv>

    *
    > sobre o Centro dediv>>Referência das Lutas Políticas no Brasil (1964-1985 – Memórias Reveladas –div>>é mais que oportuna em um número da Revista Em Pauta voltado aos movimentos e lutas sociais. Essa iniciativa do Estado brasileiro consubstanciada no Projeto Memórias Reveladas, está voltada à reunião, preservação, guarda e viabilização do acesso a acervos documentais referentes às lutas políticas ocorridas no país, no período da ditadura militar, englobando tanto as ações e movimentos de resistência como a atuação do aparato repressivo do Estado acionado sob o lema da “segurança e desenvolvimento”. Colocar esse acervo de informações históricas a serviço da pesquisa rigorosa, da reconstrução de nossa história recente, da preservação da nossa identidade e da memória coletiva é também afirmar o direito à informação e à verdade. Elucidar o passado, com olhos voltados ao futuro, construindo o novo no Brasil contemporâneo são desafios coletivos. Elesdiv>>implicam, ao nosso ver, aliar a mais ampla democratização no acesso aos arquivos por parte de todos os cidadãos brasileiros à continuidade da árduadiv>>luta pela anistia ainda inconclusa. “Para que não se esqueça, para que nunca mais aconteça”. Como já anunciava o poeta Murilo Mendes: “A memória édiv>>uma construção do futuro, mais que do passado”.div>>(O discípulo de Emaús, p. 372 div>

  14. Measuring Economic Risk Benefits of USCG Marine Safety Programs

    Science.gov (United States)

    2011-07-01

    64. Tortilla mfg 65. Snack food mfg...refining of nonferrous metal (except copper & aluminum) 177. Copper rolling, drawing, extruding & alloying...178. Nonferrous metal (except copper & aluminum) rolling, drawing, extruding & 179. Ferrous metal foundries

  15. Revista MEDICINA - Vol. 30 No. 4 (83 - Diciembre 2008 219 Editorial Atención Primaria en Salud (APS. Una estrategia para mejorar la cobertura y la calidad.

    Directory of Open Access Journals (Sweden)

    Gustavo Malagón Londoño

    2008-12-01

    Full Text Available <div data-canvas-width="393.86969999999997">Con razón ha tomado fuerza la estrategia de atención primaria, ante las dificultades que han surgido para el cumplimiento de los enunciados originales de los sistemas de seguridad social en salud, no solamente de Colombia, sino de la mayoría de los países incluyendo los más desarrollados. Los propósitos de equidad, cobertura universal y calidad no han logrado alcanzar las metas propuestasdiv> data-canvas-width="41.108333333333334">por dificultades en el desarrollo del proceso en parte por las malas interpretaciones de los enunciadosdiv> data-canvas-width="382.5133333333334">iniciales de la Ley, o por una reglamentación inconsistente y debilidad en el seguimiento y vigilancia estricta por parte de los organismos del Estado.div> data-canvas-width="356.06333333333345"> div> data-canvas-width="356.06333333333345">A partir de la década del 50 del pasado siglo, terminado el conflicto bélico mundial, se aprecia como característica de todos los países un aumento notable de los índices de pobreza, aumento de ladiv> data-canvas-width="388.0600000000003">morbilidad, a tiempo que disminuyen los niveles de atención de la salud. A pesar del concepto prevalente de que transcurridas las grandes hecatombes surgen las mejores soluciones para borrar experiencias anteriores y marcar una notable reacción a lo vivido recientemente, aspectos como el de la atención de ladiv> data-canvas-width="387.485">salud han ofrecido una lenta evolución y la añorada obertura total ha encontrado todo tipo de tropiezos.div> data-canvas-width="192.51333333333338">Esto, desde luego, ha significado un espectacular freno al desarrollo económico. div>

  16. TOPOGRAPHY AND VISCERAL MORPHOLOGY OF THE Melopsittacus undulatus, SHAW 1805 TOPOGRAFIA E MORFOLOGIA DAS VÍSCERAS DO PERIQUITO-AUSTRALIANO (Melopsittacus undulatus, SHAW 1805

    Directory of Open Access Journals (Sweden)

    Fabiana S. Matsumoto

    2009-12-01

    Full Text Available <div>The aim of this research was to study the topography and morphology of Australian parakeet (Melopsittacus undulatus viscera. Ten Australian parakeet were used (5 males and 5 females. The animals were fixed in 10% formaldehyde solution, through perfusion in the musculature and visceral cavity. Macroscopically, the Australian parakeet viscera did not show expressive differences when compared to other domestic birds’ species. Microscopically, the main difference was the presence of mechanoreceptors (Corpuscles of Pacini in the tongue, found for the first time in this psittaciform  species.div>>
    div>>KEY WORDS: Melopsittacus undulatus, morphology, topography, viscera.div>>
    div> <div>Em virtude da escassez de dados referentes à morfologia e topografia das aves em geral, o presente estudo teve como objetivo descrever a topografia e morfologia das vísceras do periquito-australiano (Melopsittacus undulatus, para assim proporcionar um conhecimento mais amplo sobre características específicas dessa espécie. Para a descrição da morfologia e topografia das vísceras foram utilizados dez periquitos, sendo cinco machos e cinco fêmeas. Os animais foram fixados com solução de formaldeído 10%, através de perfusão na musculatura e cavidade visceral. Macroscopicamente, as vísceras do periquito não apresentaram muitas diferenças comparadas a outras espécies de aves domésticas. Microscopicamente, a principal diferença estava na presença de mecanorreceptores (corpúsculos de Pacini na língua, encontrados pela primeira vez nesta espécie de psitaciforme. div>>
    div>>PALAVRAS-CHAVES: Melopsittacus undulatus, morfologia, topografia, vísceras.div>>
    div>

  17. Cultura crítica e o projeto ético-político do serviço social brasileiro: desafios contemporâneos

    Directory of Open Access Journals (Sweden)

    Josimeire de Omena Leite

    2012-09-01

    Full Text Available <div>Partindo da premissa de que é no processo de recusa e crítica aodiv>>conservadorismo que se encontram as raízes de um novo projeto profissional,div>>este artigo, a partir de revisão bibliográfica, recupera uma importante discus-são,  presente  na  atual  literatura  crítica  do  Serviço  Social  brasileiro,  acercadiv>>dos desafios contemporâneos à profissão. Especificamente aqueles postos aodiv>>processo de consolidação de uma cultura crítica no interior do Serviço Social e à efetiva implementação do seu projeto ético-político, num contexto neo-liberal. Conclui que apenas mediante uma profunda interlocução da categoria profissional com o marxismo é que se põe concretamente a possibilidade de um olhar crítico sobre o Serviço Social e a apropriação das ferramentas neces-sárias ao enfrentamento dos novos desafios à consolidação de uma cultura crítica no interior da profissão e ao processo de manutenção da hegemoniadiv>>do seu projeto ético-políticodiv>

  18. SURTO DE SARNA CORIÓPTICA EM CAPRINOS NA CIDADE DE GRAVATÁ, REGIÃO AGRESTE DO ESTADO DE PERNAMBUCO OUTBREAK OF CHORIOPTIC MANGE IN GOATS IN THE CITY OF GRAVATÁ IN PERNAMBUCO´S AGRESTE REGION

    Directory of Open Access Journals (Sweden)

    Maria Isabel de Souza

    2009-12-01

    Full Text Available <div>A sarna corióptica é de rara ocorrência em caprinos, no entanto trata-se de uma enfermidade cutânea importante, resultando em perdas econômicas decorrentes do retardo no desenvolvimento dos animais, da perda de peso e do prejuízo à indústria de couro. Desse modo, o objetivo do presente artigo é relatar a ocorrência de um surto de sarna corióptica em um rebanho caprino criado no município de Gravatá (Lat. 08° 12’ 04’’ S e Long. 35° 33’ 53’’ O, região Agreste do estado de Pernambuco. Os animais apresentavam extensas áreas de alopecia, eritema, crostas e espessamento da pele na região das axilas, peito, ventre e as faces caudal e craniomedial dos membros posteriores, além de intenso prurido. Foi realizado raspado cutâneo e identificado o ácaro Chorioptes bovis spp.div>>
    div>>PALAVRAS-CHAVES: Caprinos, Chorioptes spp, sarna.div>>
    div> <div>Chorioptic mange is of rare occurrence in goats, although it is an important skin disease resulting in economic loss due to the delay in the development of the animals, weight loss and economic losses to the leather industry. Thus, the aim of the present article was to report the occurrence of an outbreak of chorioptic mange in a goat flock reared in the city of Gravatá, (Lat. 08° 12’ 04’’ S and Long. 35° 33’ 53’’ W in Pernambuco´s Agreste region. The animals showed wide alopecia areas, erythema, crusts and skin thickness in the following areas: armpits, sternum, ventral abdomen, caudal and cranium-medial facets of the hind legs and severe scratching. Chorioptes bovis spp was identified in skin scrapings.div>>
    div>>KEY WORDS: Chorioptes spp, goats, mange.div>>
    div>

  19. A mean-field game economic growth model

    KAUST Repository

    Gomes, Diogo A.; Lafleche, Laurent; Nurbekyan, Levon

    2016-01-01

    Here, we examine a mean-field game (MFG) that models the economic growth of a population of non-cooperative, rational agents. In this MFG, agents are described by two state variables - the capital and consumer goods they own. Each agent seeks

  20. Academia Nacional de Médicina-Abbott 2008. Rotavirus, efectos adversos evitables y otras investigaciones

    Directory of Open Access Journals (Sweden)

    Alfredo Jácome Roca

    2008-12-01

    Full Text Available <div data-canvas-width="148.806">La Academia Nacional de Medicina con la colaboración de Laboratorios Abbott otorgó en noviembre dediv> data-canvas-width="33.36">2008 la segunda versión del Premio a las Ciencias Médicas, uno en las áreas de Ciencias Médicas ydiv> data-canvas-width="101.69999999999999">experimentales y otro en el área de Ciencias Clínicas.div> data-canvas-width="88.365"> div> data-canvas-width="88.365">Presentamos aqui algunas notas sobre los trabajos ganadores y los que obtuvieron menciones honoríficas. div> data-canvas-width="88.365">

    El Premio en el área de las Ciencias Básicas lo obtuvieron profesores de la Universidad Nacional de Colombia en Bogotá, pertenecientes al Laboratorio de Biología Molecular de Virus de la Facultad de Medicina y al Departamento de Química de la Facultad de Ciencias. Se trata de los investigadores Carlos Arturo Guerrero Fonseca, Martha Calderón, Orlando Acosta y Fanny Guzmán.

    El trabajo se titula "Interferencia de la infección por rotavirus mediante la inhibición de la actividad de
    la proteína disulfuro isomerasa (PDI de la membrana celular de las líneas MA 104 y Caen-2".

    div>

  1. Diferencias y identidades sexuales: lecturas críticas desde la economía y la ciencia política

    Directory of Open Access Journals (Sweden)

    Mónica Solange de Martino Bermúdez

    2012-04-01

    Full Text Available <div> Relatamos aqui reflexões derivadas do projeto de pesquisa intitulado Ser Homens, Ser Pais em Contextos de Pobreza. Tentamos desvendar o quediv>>está em jogo além do respeito à diversidade sexual. Nossa hipótese é que as minorias sexuais têm uma tendência à hipercorreção cívica, respondendodiv>>aos sonhos mais pesados da racionalidade ocidental. Essa tendência reduziria o seu potencial político/emancipatório. Da mesma forma, acreditamos que desafia teórica e eticamente ao Trabalho Social, na medida em que a adesão irrefletida ao respeito à diversidade não faz visível a relação daquela comdiv>>certas características da cultura do capitalismo tardio.div>

  2. Ideological Configurations and Prediction of Attitudes toward Immigrants in Chile and Germany

    OpenAIRE

    Carvacho, Hector

    2010-01-01

    <div>The concept of ideological configuration is proposed to refer to a complex of ideological attitudes – Right-Wing Authoritarianism (RWA) and Social Dominancediv>>Orientation (SDO) – based on a shared core of derogation of outgroups. This concept is used in two surveys, in Chile and in Germany, to predictdiv>>attitudes toward foreigners. Analyses using structu...

  3. Human Birth Weight and Reproductive Immunology: Testing for Interactions between Maternal and Offspring KIR and HLA-C Genes.

    Science.gov (United States)

    Clark, Michelle M; Chazara, Olympe; Sobel, Eric M; Gjessing, Håkon K; Magnus, Per; Moffett, Ashley; Sinsheimer, Janet S

    2016-01-01

    Maternal and offspring cell contact at the site of placentation presents a plausible setting for maternal-fetal genotype (MFG) interactions affecting fetal growth. We test hypotheses regarding killer cell immunoglobulin-like receptor (KIR) and HLA-C MFG effects on human birth weight by extending the quantitative MFG (QMFG) test. Until recently, association testing for MFG interactions had limited applications. To improve the ability to test for these interactions, we developed the extended QMFG test, a linear mixed-effect model that can use multi-locus genotype data from families. We demonstrate the extended QMFG test's statistical properties. We also show that if an offspring-only model is fit when MFG effects exist, associations can be missed or misattributed. Furthermore, imprecisely modeling the effects of both KIR and HLA-C could result in a failure to replicate if these loci's allele frequencies differ among populations. To further illustrate the extended QMFG test's advantages, we apply the extended QMFG test to a UK cohort study and the Norwegian Mother and Child Cohort (MoBa) study. We find a significant KIR-HLA-C interaction effect on birth weight. More generally, the QMFG test can detect genetic associations that may be missed by standard genome-wide association studies for quantitative traits. © 2017 S. Karger AG, Basel.

  4. La primera operación del corazón en Antioquia

    OpenAIRE

    Tiberio Alvarez Echeverri

    1995-01-01

    <div>e dice que Hipócrates no describió ninguna patología del corazón. Creyó que órgano tandiv>>noble no sufriría enfermedad. Aristóteles agregó que si el corazón era lesionado no funcionarían los órganos dependientes. Galeno, con sus observaciones en los gladiadores heridos, estableció que ";cuando la herida penetra en una de las cámarasdiv>>cardíacas, la persona muere instantáneamente por pérdida de sangre...div>

  5. A Priori Bounds for Models with Singularities

    KAUST Repository

    Gomes, Diogo A.

    2016-09-14

    Here, we discuss two problems—an MFG with a logarithmic nonlinearity and an MFG with congestion effects. Stationary versions of these two problems were considered in Chap. 7 However, the techniques for time-dependent problems are substantially different from the ones used in the stationary case.

  6. A Priori Bounds for Models with Singularities

    KAUST Repository

    Gomes, Diogo A.; Pimentel, Edgard A.; Voskanyan, Vardan K.

    2016-01-01

    Here, we discuss two problems—an MFG with a logarithmic nonlinearity and an MFG with congestion effects. Stationary versions of these two problems were considered in Chap. 7 However, the techniques for time-dependent problems are substantially different from the ones used in the stationary case.

  7. CHORDAE TENDINEAE FREQUENCY IN THE MITRAL VALVE OF SANTA INÊS SHEEP (Ovis Aries, Linnaeus 1758 FREQUÊNCIA DE CORDAS TENDÍNEAS DA VALVA MITRAL DO CORAÇÃO DE OVINOS (Ovis aries, LINNAEUS 1758 DA RAÇA SANTA INÊS

    Directory of Open Access Journals (Sweden)

    Fábio Ferreira de Queiroz

    2009-12-01

    Full Text Available <div>The aim of this work is to investigate the frequency of tendinous cords in the left atrioventricular valve complex (LAVC of the heart of sheeps of the Santa Inês breed. The experiments involved 40 hearts prepared in 10% formalin solution and dissected for the retreat of LVC. The LAVC was analyzed for tendinous cords counting and the total of these cords in each heart varied from 10 to 27 and the total oriented to the commissure of valve varied from two to five cords, all coming from papilar sub-auricular and papilar sub-atrial muscles. Higher frequency was observed in hearts with three cords that were oriented to commissure. The results suggest no anatomic standardization in the amount of tendinous cords in the heart of the sheep of the Santa Inês.div>>
    div>>Keywords:  Frequency, heart, morphology, sheep, tendinous cords.div> <div>Este trabalho teve como objetivo investigar a frequência de cordas tendíneas no complexo valvar atrioventricular esquerdo (CVAE do coração de ovinos da raça Santa Inês. Os ensaios foram realizados em quarenta órgãos preparados com a utilização de solução de formol a 10% e dissecados para a retirada do CVAE, classificando-se e quantificando-se as cordas tendíneas, cujo número variou de 10 a 27, bem como as que se orientavam à comissura entre as válvulas, variando em número de duas a cinco cordas, saindo dos músculos papilares subauricular e subatrial. Corações com três cordas que se orientavam à comissura apresentaram maior frequência. Os resultados sugerem a inexistência de uma padronização anatômica na quantidade de cordas tendíneas no coração do ovino da raça Santa Inês.div>>
    div>>Palavra-chaveS: Cordas tendíneas, coração, frequência, morfologia, ovino.div>>
    div>

  8. fMRI activation in the middle frontal gyrus as an indicator of hemispheric dominance for language in brain tumor patients: a comparison with Broca's area.

    Science.gov (United States)

    Dong, Jian W; Brennan, Nicole M Petrovich; Izzo, Giana; Peck, Kyung K; Holodny, Andrei I

    2016-05-01

    Functional MRI (fMRI) can assess language lateralization in brain tumor patients; however, this can be limited if the primary language area-Broca's area (BA)-is affected by the tumor. We hypothesized that the middle frontal gyrus (MFG) can be used as a clinical indicator of hemispheric dominance for language during presurgical workup. Fifty-two right-handed subjects with solitary left-hemispheric primary brain tumors were retrospectively studied. Subjects performed a verbal fluency task during fMRI. The MFG was compared to BA for fMRI voxel activation, language laterality index (LI), and the effect of tumor grade on the LI. Language fMRI (verbal fluency) activated more voxels in MFG than in BA (MFG = 315, BA = 216, p hemispheric MFG and BA were positively correlated (r = 0.69, p hemispheric dominance for language using a measure of verbal fluency and may be an adjunct measure in the clinical determination of language laterality for presurgical planning.

  9. Phenotypic comparison of Caucasian and Asian women with polycystic ovary syndrome: a cross-sectional study.

    Science.gov (United States)

    Wang, Erica T; Kao, Chia-Ning; Shinkai, Kanade; Pasch, Lauri; Cedars, Marcelle I; Huddleston, Heather G

    2013-07-01

    To determine whether manifestations of polycystic ovary syndrome (PCOS), particularly androgen excess, differ between Caucasian and Asian women in the San Francisco Bay Area. Cross-sectional study. Multidisciplinary PCOS clinic at a tertiary academic center. 121 Caucasian and 28 Asian women, aged 18-44, examined between 2006 and 2011 with PCOS verified by a reproductive endocrinologist and dermatologist according to the Rotterdam criteria. Transvaginal ultrasounds, comprehensive dermatologic exams, and serum testing. Hirsutism defined as a modified Ferriman-Gallwey (mFG) score ≥ 8, acne, androgenic alopecia, and biochemical hyperandrogenism. Caucasian and Asian women had a similar prevalence of all measures of androgen excess. Both groups had similar total mFG scores and site-specific mFG scores, except Asian women had a lower site-specific mFG score for the chest. Although Asian women were more likely to use laser hair removal, the results were unchanged when the women with a history of laser hair removal were excluded. Caucasian and Asian women with PCOS living in the same geographic region had a similar prevalence of hirsutism as well as other markers for androgen excess. Further studies are necessary to evaluate the need for ethnic-specific mFG scores in women with PCOS. Copyright © 2013 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

  10. Mechanical Adaptivity as a Process: Implications to New Materials and Material System Design

    Science.gov (United States)

    2012-08-01

    Mfg / Origami HT Thermal Shape Memory PhotoChem- Mechanical Autonomic Chemo-Mechanical Building Blocks Predictive Models...structure Farkas et al. Chaos 5 1995 Bishop et al. JACS, 2005 Controlling oscillations through medium selection and geometry Controlling...Additive Mfg / Origami HT Thermal Shape Memory PhotoChem- Mechanical Autonomic Chemo-Mechanical Building Blocks Predictive Models

  11. BLUETONGUE VIRUS ANTIBODIES DETECTIONS IN SHEEP FROM ARAÇATUBA REGION –SAO PAULO, BRAZIL DETECÇÃO DE ANTICORPOS CONTRA O VÍRUS DA LÍNGUA AZUL EM OVINOS NA REGIÃO DE ARAÇATUBA – SÃO PAULO, BRASIL

    Directory of Open Access Journals (Sweden)

    Adriana Hellmeister de Campos Nogueira

    2009-12-01

    Full Text Available <div>Bluetongue (BT is an infectious, insect-born viral disease of ruminants. The causative agent of BT is bluetongue virus (BTV that belongs to the family Reoviridae genus Orbivirus. Insect vectors in the genus Culicoides transmit this virus. BT affects domestic and wild ruminants, however small ruminants are considered the most affected specie. The aim of the study was to detect antibodies against BTV in commercial sheep farms, of the Northeastern region of Sao Paulo State, Brazil. A total of 1002 sera samples collected from adult sheep (above 1 year-old, comprising a total of 31 farms, were screened for the presence of BTV antibodies, by agar gel immunodiffusion test (AGID and ELISA-CFS (Enzyme Linked Immunosorbent Assay – competitive solid phase, both produced by Pan American Center of FMDV. From a total of 1002 samples, 651 (65% were positive by AGID and 742 (74.1%, were positive by ELISA-CFS. These results suggest that the BTV is widespread among farms, probably causing subclinical infections.div>>
    div>>KEY WORDS: AGID, bluetongue virus, ELISA-CFS, seroepidemiological survey.div>>
    div> <div>A língua azul é uma doença viral, cujo agente etiológico pertence à família Reoviridae, gênero Orbivirus, transmitida por um vetor (artrópode hematófago, do gênero Culicoides. Os animais acometidos são ruminantes domésticos e selvagens, porém os pequenos ruminantes são os mais afetados. O estudo teve como objetivo detectar a presença de anticorpos para língua azul em ovinos da região de Araçatuba, por possuir um rebanho expressivo e condições climáticas favoráveis à multiplicação de insetos. Foram analisadas 1.002 amostras de soros ovinos, provenientes de 31 cabanhas, pelas provas de imunodifusão dupla em gel de ágar (AGID e ELISA (Enzyme Linked immunosorbent Assay de competição da fase sólida (ELISA CFS, provenientes do Centro Panamericano de Febre Aftosa. Desses soros, 651 (65% foram

  12. LUTEINIZING HORMONE SECRETION IN NELLORE HEIFER’S AFTER WEANING TO FIRST OVULATION CONCENTRAÇÃO DE LH EM NOVILHAS DA RAÇA NELORE DA DESMAMA À PRIMEIRA OVULAÇÃO

    Directory of Open Access Journals (Sweden)

    Daniel Cardoso

    2009-12-01

    Full Text Available <div>The aim was to evaluate the LH secretion in B. indicus heifers, on the presence or absence of gonadal steroid, generating information about the mechanisms evolved on sexual maturation in Nellore heifers. LH and progesterone concentration were quantified by RIA. First ovulation was determined by plasma progesterone concentration (>1 ng/ml. Greater mean LH concentrations was observed in ovariectomized (OVX; P?0.05 compared to intact heifers (INT. Mean LH concentration increased (P?0.05 during the sexual maturation, in both intact and ovariectomized heifers. The number of peaks was higher (P?0.05 in ovariectomized heifer. The results suggest decrease in estradiol hypothalamus negative feedback during Nellore heifer’s sexual maturation. It was possible to conclude that in pre-pubertal Nellore heifers the increase on positive gonadal steroids feedback was necessary to increase LH secretion before first ovulation.div>>
    div>>KEY WORDS: Cattle, endocrinology, hypothalamus, puberty, steroids.div> <div>O presente trabalho teve por objetivo investigar a variação na secreção de LH na presença ou não de esteroides gonadais e, dessa forma, gerar informações sobre os mecanismos envolvidos na maturação sexual de novilhas da raça Nelore. Quantificou-se a concentração de LH e progesterona por radioimunoensaio. A primeira ovulação foi determinada pela concentração plasmática de progesterona (>1 ng/ml. As novilhas ovariectomizadas (OVX apresentaram maior concentração basal de LH (P?0,05 que as novilhas inteiras (INT. Houve uma concentração de LH durante a maturação sexual, tanto nas novilhas INT quanto nas OVX. O número de picos de secreção de LH foi maior (P?0,05 nas novilhas OVX. Os resultados indicam uma diminuição da sensibilidade do hipotálamo aos esteroides gonadais durante o processo de maturação sexual nas novilhas da raça Nelore. Conclui-se que, em novilhas pré-púberes da raça Nelore, o

  13. EFFECT OF TIME AND TEMPERATURE OF REFRIGERATION IN THE DEVELOPMENT OF PSYCHROTROPHIC MICRORGANISMS IN COOLED RAW MILK COLLECTED IN THE MACROREGION OF GOIÂNIA – GO EFEITO DO TEMPO E DA TEMPERATURA DE REFRIGERAÇÃO NO DESENVOLVIMENTO DE MICRORGANISMOS PSICROTRÓFICOS EM LEITE CRU REFRIGERADO COLETADO NA MACRORREGIÃO DE GOIÂNIA – GO

    Directory of Open Access Journals (Sweden)

    Antônio Nonato de Oliveira

    2009-12-01

    Full Text Available <div>The objective of the research were evaluated the effect of storage time and of refrigeration temperature under the counting of psychrotrophics microrganisms and proteolytics psychrotrophics in refrigerated raw milk samples. In the period of August the September of 2005 34 refrigerated raw milk samples were collected of refrigeration tanks, being 29 individuals and five collectives. Milk was proceeding from bovine flocks. For the collection of the samples followed a route determined for the industry located in the macroregion of Goiânia – GO, Brazil. For the microbiological evaluation was carried the standard plate count method of psychrotrophics microrganisms and proteolytics psychrotrophics. For the determination and quantification of the glycomacropeptide (GMP were adopted methodology proposal in Brazil (1991. The counting of psychrotrophics microrganisms and proteolytics psychrotrophics increased with the storage time of refrigerated bovine milk. Were observed the inadequate tanks were observed e presence of GMP for the High Performance Liquid Chromatography (HPLC was not evidenced.div>>
    div>>KEY WORDS: Proteolysis, Pseudomonas spp, raw milk.div> <div>O objetivo da pesquisa foi avaliar o efeito do tempo de estocagem e da temperatura de refrigeração sob a contagem de microrganismos psicrotróficos e psicrotróficos proteolíticos em amostras de leite cru refrigerado. No período de agosto a setembro de 2005 coletaram-se 34 amostras de leite cru refrigerado de tanques de expansão, sendo 29 individuais e cinco coletivos. Para a coleta das amostras seguiu-se uma rota determinada pela indústria localizada na macrorregião de Goiânia, GO. Para a avaliação microbiológica, foi realizada a contagem-padrão em placas de microrganismos psicrotróficos e psicrotróficos proteolíticos. Para a determinação e quantificação do caseinomacropeptídeo (CMP, adotou-se a metodologia proposta em BRASIL (1991. A contagem de

  14. Ética Médica y Sociedad Actual

    Directory of Open Access Journals (Sweden)

    Hernando Forero Caballero

    1998-12-01

    Full Text Available <div>Definición

>
div>>La medicina es una de las profesiones más antiguas, de condición científica y respetable, cuya función social humanitaria y humanística le imprime el más alto rango de aproximación a la existencia del ser Humano, con compromiso deontológico.div>> div>>La asistencia médica como acto plenamente humano posee una esencial dimensión ética, que le imprime su particular sentido y es el fundamento de la profesión del médico.div>> div>>“Etica” viene del griego etnos, que significa la raíz o fuente de todos los actos particulares y costumbres como interpretación universal.div>> div>>“Moral” del latín mos, significa práctica, comportamiento o conducta, hábito o costumbre. Con tendencia a ser particular.div>> div>>La ética es una ciencia práctica, normativa de los principios de la moralidad de los actos humanos.div>> div>>La Deontología comprende el conjunto de reglas que enmarcan la conducta del profesional no técnico, con orientación hacia un objetivo humanístico y humanitario en un sentido noble, culto y espiritual.div>> div>>La Deontología es la parte concreta y práctica de la ética porque en ella se humanizan las actividades realizadas por el profesional, en cuanto se refiere a la idealización del bien, orientado hacia el ser humano en función social e individual.div>> div>>La Deontología determina los deberes que han de cumplirse en circunstancias sociales específicas, particularmente dentro de una profesión. Se considera la ciencia de los deberes, con el significado de lo obligatorio, justo y adecuado.div>> div>>La Deontología médica tiene como fundamento la moral individual del médico.div>> div>>La ética constituye una disciplina estructurada y sistematizada con principios, normas y valores morales. Es una sola universal

  • CAREERS, DESTINIES AND ROMANIAN NATIONAL ATTITUDES IN BESSARABIA: CONSTANTIN STERE AND ROMANIAN LIFE JOURNAL

    OpenAIRE

    Răducu Rușeț

    2016-01-01

    This historical research entitled Careers, destinies and Romanian national attitudes in Bessarabia: Constantin Stere and Romanian Life Journal aims to evoke some aspects of biographical and journalistic activity of the writer, publicist and politician Constantin Stere. This biographic-intellectual and diachronic reconstitution of personality of Bassarabian Constantin Stere approach aims to bring on the first stage of actual historiography an exposure of his life. The author div...

  • MACROSCOPIC, MORPHOLOGIC AND MORPHOMETRIC ASPECTS OF THE SPLEEN OF RATS AFTER TOTAL CLAMPING OF THE HEPATIC PEDICLE ASPECTOS MACROSCÓPICOS, MORFOLÓGICOS E MORFOMÉTRICOS DO BAÇO DE RATOS APÓS O CLAMPEAMENTO TOTAL DO PEDÍCULO HEPÁTICO

    Directory of Open Access Journals (Sweden)

    Lázaro Manoel Camargo

    2009-12-01

    Full Text Available <div>One of the complications of hepatic pedicle total clamping is the splanchnic congestion and consequently a splenic congestion. The aim of this study was to observe the macro and microscopic alterations that occurred in the spleen during an ischemia produced by the hepatic pedicle clamping. Fourth male rats were divided in four groups of ten animals each. The control group (C was not submitted to ischemia and the experimental groups (E1, E2 and E3 were submitted to the total clamping during 10, 20 and 30 minutes, respectively. After these periods, spleen fragments were collected and histological analyzed by the eosin-hematoxilin and ferric ferrocyanide staining technique. The results showed microscopic alterations at the E1, E2 and E3    groups that permitted to conclude that the total clamping of the hepatic pedicle promote intense vascular congestion, increase of the hemosiderin granules, decrease of the white pulp and increase of the red pulp, being these alterations more pronounced at the 30 minutes.div>>
    div>>KEY WORDS: Congestion, hemossiderina, spleen, rats.div> <div>Uma das complicações do clampeamento total do pedículo hepático é a congestão esplâncnica e, consequentemente, a congestão esplênica. Este trabalho teve como objetivo observar as alterações macroscópicas, morfológicas e morfométricas que ocorreram no baço com a isquemia produzida pelo clampeamento do pedículo hepático. Para tanto, utilizaram-se quarenta ratos machos, divididos em quatro grupos de dez animais. Não se submeteu o grupo controle (C à isquemia. Por sua vez, submeteram-se os grupos experimentais (E1, E2 e E3 ao clampeamento total por dez, vinte e trinta minutos, respectivamente. Após esses períodos, fragmentos do baço foram retirados e analisados histologicamente pela técnica de Hematoxilina-eosina e Ferrocianeto-férrico. Os resultados mostraram alterações microscópicas nos grupos E1, E2 e E3, que permitem

  • A role of right middle frontal gyrus in reorienting of attention: a case study.

    Science.gov (United States)

    Japee, Shruti; Holiday, Kelsey; Satyshur, Maureen D; Mukai, Ikuko; Ungerleider, Leslie G

    2015-01-01

    The right middle fontal gyrus (MFG) has been proposed to be a site of convergence of the dorsal and ventral attention networks, by serving as a circuit-breaker to interrupt ongoing endogenous attentional processes in the dorsal network and reorient attention to an exogenous stimulus. Here, we probed the contribution of the right MFG to both endogenous and exogenous attention by comparing performance on an orientation discrimination task of a patient with a right MFG resection and a group of healthy controls. On endogenously cued trials, participants were shown a central cue that predicted with 90% accuracy the location of a subsequent peri-threshold Gabor patch stimulus. On exogenously cued trials, a cue appeared briefly at one of two peripheral locations, followed by a variable inter-stimulus interval (ISI; range 0-700 ms) and a Gabor patch in the same or opposite location as the cue. Behavioral data showed that for endogenous, and short ISI exogenous trials, valid cues facilitated responses compared to invalid cues, for both the patient and controls. However, at long ISIs, the patient exhibited difficulty in reverting to top-down attentional control, once the facilitatory effect of the exogenous cue had dissipated. When explicitly cued during long ISIs to attend to both stimulus locations, the patient was able to engage successfully in top-down control. This result indicates that the right MFG may play an important role in reorienting attention from exogenous to endogenous attentional control. Resting state fMRI data revealed that the right superior parietal lobule and right orbitofrontal cortex, showed significantly higher correlations with a left MFG seed region (a region tightly coupled with the right MFG in controls) in the patient relative to controls. We hypothesize that this paradoxical increase in cortical coupling represents a compensatory mechanism in the patient to offset the loss of function of the resected tissue in right prefrontal cortex.

  • Milk fat globule-epidermal growth factor-factor VIII attenuates sepsis-induced acute kidney injury.

    Science.gov (United States)

    Cen, Cindy; Aziz, Monowar; Yang, Weng-Lang; Zhou, Mian; Nicastro, Jeffrey M; Coppa, Gene F; Wang, Ping

    2017-06-01

    Acute kidney injury (AKI) is most commonly caused by sepsis in critically ill patients, and it is associated with high morbidity and mortality. The pathophysiology of sepsis-induced AKI is generally accepted to include direct inflammatory injury, endothelial cell dysfunction, and apoptosis. Milk fat globule-epidermal growth factor-factor VIII (MFG-E8) is a secretory glycoprotein with a known role in the enhancement of apoptotic cell clearance and regulation of inflammation. We hypothesize that administration of recombinant mouse MFG-E8 (rmMFG-E8) can protect mice from kidney injuries caused by sepsis. Sepsis was induced in 8-wk-old male C57BL/6 mice by cecal ligation and puncture (CLP). rmMFG-E8 or phosphate-buffered saline (vehicle) was injected intravenously at a dosage of 20 μg/kg body weight at time of CLP (n = 5-8 mice per group). After 20 h, serum and renal tissue were harvested for various analyses. The renal injury markers blood urea nitrogen (BUN) and creatinine were determined by enzymatic and chemical reactions, respectively. The gene expression analysis was carried out by real-time quantitative polymerase chain reaction. At 20 h after CLP, serum levels of BUN and creatinine were both significantly increased in the vehicle group compared with the sham group, whereas the mice treated with rmMFG-E8 had a significant reduction in BUN and creatinine levels by 28% and 24.1%, respectively (BUN: 197.7 ± 23.6 versus 142.3 ± 20.7 mg/dL; creatinine: 0.83 ± 0.12 versus 0.63 ± 0.06 mg/dL; P sepsis through inhibiting the production of proinflammatory cytokines and chemokine, as well as through the activation of endothelial cells. Thus, MFG-E8 may have a therapeutic potential for treating AKI induced by sepsis. Copyright © 2017 Elsevier Inc. All rights reserved.

  • EFFECT OF IMPERMEANT CRYOPROTECTANTS ON THE IN VITRO VIABILITY OF FROZEN SPERMATOZOA OF SWISS-ALBINA AND BALB/C MICE (Mus musculus EFEITO DE CRIOPROTETORES IMPERMEÁVEIS SOBRE A VIABILIDADE IN VITRO DE ESPERMATOZOIDES CONGELADOS DE CAMUNDONGOS (Mus musculus DAS LINHAGENS SWISS-ALBINA e BALB/c

    Directory of Open Access Journals (Sweden)

    Antonio Sergio Varela Junior

    2009-12-01

    Full Text Available <div>The objective of this study was to evaluate the effect of three disaccharides (sucrose, threalose and lactose used as nonpenetrating cryoprotectants in extender for mice semen. The parameters evaluated were sperm motility (MOT and cleavage rate (CLV after in vitro fertilization in the SWISS-ALBINA and BALB/c lines. The treatments were S1=sucrose; S2=threalose; S3=lactose, for SWISS-ALBINA; and B1=lactose; B2=threalose for BALB/c.  MOT was evaluated after: thawing (THA, centrifugation and re-suspension in P-1 medium (CEN and after 10 minutes of incubation (10M. The MOT for the SWISS-ALBINA line was higher for S2 (P<0.001 in the 3 evaluated steps (47% at DES; 66.5% at CEN and 67.2% at 10M than for S1 (32.5% at DES; 51.5% at CEN and 47.7% at 10M and S3 (30% at DES, 46.5% at CEN and 32.7% at 10M. For the BALB/c line, MOT was superior for B2 than for B1 (P<0.001. Thus, the tested disaccharides, especially threalose, can be recommended for freezing of mice sperm.div>>
    div>>KEY WORDS: Cryopreservation, disaccharides, mice, semen. div>>
    div> <div>O trabalho objetivou avaliar os efeitos dos dissacarídeos sacarose, trealose e lactose, como crioprotetores impermeáveis à membrana plasmática em diluentes para criopreservação de sêmen de camundongos. Para avaliação do sêmen utilizaram-se os seguintes parâmetros: motilidade progressiva (MOT das células espermáticas, e a taxa de clivagem embrionária (TXCL obtida por meio de fertilização in vitro, nas linhagens SWISS-ALBINA e BALB/c. Os tratamentos avaliados foram: S1=sacarose; S2=trealose; S3=lactose, para SWISS-ALBINA e B1=lactose; B2=trealose para BALB/c. Avaliou-se a MOT durante as seguintes etapas: descongelação (DES, centrifugação e ressuspensão no meio P-1 (CEN e após dez minutos de incubação (10M. A MOT no S2 para a linhagem SWISS-ALBINA nas três etapas (47% no DES; 66,5% na CEN e 67,2% no 10M foi superior (P<0,001 a S1 (32,5% no DES; 51,5% no

  • ¿El bastón de Esculapio o el Caduceo de Mercurio?

    Directory of Open Access Journals (Sweden)

    Jorge Cavelier Gaviria

    1992-12-01

    Full Text Available <div>Complacidos publicamos el interesante estudio sobre el bastón de Esculapio en contraposición con el caduceo de Mercurio, del Académico Jorge Cavelier Gaviria, ex-presidente de nuestra corporación.div>> div>>El doctor Cavelier Gaviria, en forma terminante y didáctica, aclara una duda que, esporádicamente, se presenta sobre el emblema o insignia de nuestra profesión médica, que, como bien lo explica el distinguido académico, es el bastón de Esculapio. div>> div>>Debate sobre el símbolodiv>>Nos referimos aquí al símbolo de Esculapio, que utiliza una sola serpiente, en contraposición con el caduceo de Hermes, con dos serpientes gemelas entrelazadas.div>> div>>Para los griegos la serpiente, figura simbólica en la mitología y en los textos sagrados antiguos, se relacionaba con los poderes del conocimiento, la sabiduría, las profecías, los sueños, la curación y la regeneración.div>> div>

    Asclepio
    > div>>Asclepio (o el Esculapio romano es el arquetipo del médico, un sanador devoto, tanto compasivo como hábil, sin que esté claro que haya existido como médico de Tesalia alrededor del año 1200 a.C. o que haya sido solamente una deidad médica mitológica.div>> div>>Según la leyenda, Asclepio, el hijo de Apolo y la ninfa Coronis, recibió tutoría del centauro Kyron en el arte de la cirugía. Logró tal éxito al impartir salud a pacientes gravemente enfermos que Pluto lo acusó de estar disminuyendo la población en Hades y arregló su muerte, por medio de un rayo de Zeus (Zeus posteriormente restituyó aAsclepio. Se dice que Hipócrates es el décimo octavo (180. descendiente de Asclepio. Después de la muerte de Asclepio surgieron los templos dedicados al culto de sus métodos y enseñanzas, y hacia el año 420 a. C.los había en número superior a los 200 en toda Grecia.div>

    1. Characterization of Early Cortical Neural Network ...

      Science.gov (United States)

      We examined the development of neural network activity using microelectrode array (MEA) recordings made in multi-well MEA plates (mwMEAs) over the first 12 days in vitro (DIV). In primary cortical cultures made from postnatal rats, action potential spiking activity was essentially absent on DIV 2 and developed rapidly between DIV 5 and 12. Spiking activity was primarily sporadic and unorganized at early DIV, and became progressively more organized with time in culture, with bursting parameters, synchrony and network bursting increasing between DIV 5 and 12. We selected 12 features to describe network activity and principal components analysis using these features demonstrated a general segregation of data by age at both the well and plate levels. Using a combination of random forest classifiers and Support Vector Machines, we demonstrated that 4 features (CV of within burst ISI, CV of IBI, network spike rate and burst rate) were sufficient to predict the age (either DIV 5, 7, 9 or 12) of each well recording with >65% accuracy. When restricting the classification problem to a binary decision, we found that classification improved dramatically, e.g. 95% accuracy for discriminating DIV 5 vs DIV 12 wells. Further, we present a novel resampling approach to determine the number of wells that might be needed for conducting comparisons of different treatments using mwMEA plates. Overall, these results demonstrate that network development on mwMEA plates is similar to

    2. Division V: Commission 42: Close Binaries

      Science.gov (United States)

      Ribas, Ignasi; Richards, Mercedes T.; Rucinski, Slavek; Bradstreet, David H.; Harmanec, Petr; Kaluzny, Janusz; Mikolajewska, Joanna; Munari, Ulisse; Niarchos, Panagiotis; Olah, Katalin; Pribulla, Theodor; Scarfe, Colin D.; Torres, Guillermo

      2015-08-01

      Commission 42 (C42) co-organized, together with Commission 27 (C27) and Division V (Div V) as a whole, a full day of science and business sessions that were held on 24 August 2012. The program included time slots for discussion of business matters related to Div V, C27 and C42, and two sessions of 2 hours each devoted to science talks of interest to both C42 and C27. In addition, we had a joint session between Div IV and Div V motivated by the proposal to reformulate the division structure of the IAU and the possible merger of the two divisions into a new Div G. The current report gives an account of the matters discussed during the business session of C42.

    3. Rat fetal ventral mesencephalon grown as solid tissue cultures

      DEFF Research Database (Denmark)

      Höglinger, G U; Sautter, J; Meyer, Morten

      1998-01-01

      in vitro (DIV) in the presence or absence (controls) of BDNF [100 ng/ml]. The dopamine content in the culture medium, analyzed by HPLC, was significantly higher (4-5 fold) in the BDNF group at DIV 8 and DIV 12 compared to the corresponding control levels (40 pg/ml). The number of tyrosine hydroxylase...

    4. DIvERTICULE DE ZENKER

      African Journals Online (AJOL)

      origine de complications respiratoires aigues (détresse respiratoire aigue, pneumopathie d'inha- lation) ou chronique (bronchite chronique, asthme) qui surviennent dans 20 % des cas [8]. L'examen clinique est souvent normal. Cependant une.

    5. Boundaries, Discrimination, and Interethnic Conflict in Xinjiang, China

      Directory of Open Access Journals (Sweden)

      Enze Han

      2010-12-01

      Full Text Available <div>The Xinjiang Uighur Autonomous Region has been afflicted by Uighur political activism and ethnic violence for the past few decades. Interethnic relations between the Uighurs and Han Chinese have been extremely tense. Why is Xinjiang so vulnerable to interethnic violence? Why are intergroupdiv>>dynamics between the Uighurs and Han Chinese so volatile? This paper examines Uighur–Han Chinese relations in contemporary Xinjiang and probes conditions that facilitate interethnic violence. Utilizing Fredrik Barth’s approach to ethnicity that emphasizes boundaries, this paper examines in detail how the rigid interethnic boundary between the Uighurs and Han Chinese has been constructed and strengthened in Xinjiang. Perceived differences have generated mutual distrust and discrimination between the two groups that make intergroup communication and understanding difficult and therefore very limited. In situations such as that in Xinjiang, where a rigid intergroup boundary is in place and civic engagements across groups are lacking, intergroup conflict isdiv>>extremely hard to avoid.div>

    6. Magnetoelectric Transverse Gradient Sensor with High Detection Sensitivity and Low Gradient Noise

      OpenAIRE

      Zhang, Mingji; Or, Siu Wing

      2017-01-01

      We report, theoretically and experimentally, the realization of a high detection performance in a novel magnetoelectric (ME) transverse gradient sensor based on the large ME effect and the magnetic field gradient (MFG) technique in a pair of magnetically-biased, electrically-shielded, and mechanically-enclosed ME composites having a transverse orientation and an axial separation. The output voltage of the gradient sensor is directly obtained from the transverse MFG-induced difference in ME vo...

    7. Eastern European Transformation and Youth Attitudes toward Violence

      Directory of Open Access Journals (Sweden)

      Berit Haußmann

      2011-12-01

      Full Text Available <div>>This cross-national examination of the motives behind adolescent approval of violence in major cities in Germany and four Eastern European transformation societies (Czech Republic, Poland, Russia, Slovenia draws on Institutional Anomie Theory (IAT, which leads us to expect higher instrumental motivation for violence among adolescents in the transforming societies. Differences in institutional structure and cultural orientations between Germany and the Eastern European societies are assessed using data from ILO and ESS. Analysis of the different motives for violence is based on data collected by the Criminological Research Institute of Lower Saxony (KFN in Kraków, Volgograd, Ljubljana, Plzen, and Hamburg. Comparability and cross-cultural interpretability of the violencediv>>attitude measure is assessed by applying confirmatory factor analyses in multi-group comparisons. A lack of sufficient data meant that specific assumed linkages as implied by IAT could not be established, but the results for a specific instrumental/utilitarian motive for violence and for institutional structure and cultural orientations point to the utility of applying insights from IAT to understanding the dynamics of violence within the Eastern European context of transformation.div>>We find empirical indications that specific features of the family mediate the “Eastern effect” on the instrumental/utilitarian motive. Further research is needed to discover whether economic dominance affects motives for youth violence indirectly via the socialization provided by non-economic institutions rather than directly via cultural orientations.div>>

    8. Assessment of the Greenland Halibut Stock Component in NAFO Subarea 0 + Division 1A offshore + Division 1D-1F

      DEFF Research Database (Denmark)

      Jørgensen, Ole A; Treble, M.A.

      2014-01-01

      series. A combined standardized CPUE series from Div. 0A + 1AB has been stable since 2002. A combined CPUE series from Div. 1CD+0B decreased between 2011 and 2012 but increased slightly in 2013 and is above the level in 1990-2004. A combined standardized CPUE series from SA0 and 1 combined has been...... increasing gradually since 1997 and was in 2013 at the third highest level seen since 1990. CPUE series from the gill net in Div. 0A and Div. 0B were close to or at the highest level in the time series....

    9. Experimental Investigation of Muon-Catalyzed $dt$ Fusion in Wide Ranges of $D/T$ Mixture Conditions

      CERN Document Server

      Bom, V R; Demin, D L; van Eijk, C W E; Faifman, M P; Filchenkov, V V; Golubkov, A N; Grafov, N N; Grishenchkin, S K; Gritsaj, K I; Klevtsov, V G; Konin, A D; Kuryakin, A V; Medved', S V; Musyaev, R K; Perevozchikov, V V; Rudenko, A I; Sadetsky, S M; Vinogradov, Yu I; Yukhimchuk, A A; Yukhimchuk, S A; Zinov, V G; Zlatoustovskii, S V

      2004-01-01

      A vast program of the experimental investigation of muon-catalyzed $dt$ fusion was performed at the JINR Phasotron. Parameters of the $dt$ cycle were obtained in a wide range of $D/T$ mixture conditions: temperatures of $20\\div 800$ K, densities of $0.2\\div1.2$ LHD and tritium concentrations of $15\\div 86\\%$. The results obtained are summarized.

    10. The effect of magnetic nanoparticle concentration on the structure organisation of a microferrogel

      Science.gov (United States)

      Ryzhkov, A. V.; Melenev, P. V.; Balasoiu, M.; Raikher, Yu L.

      2018-03-01

      Coarse-grained molecular dynamics simulation is applied to study the structural response of micro-sized magnetopolymer objects – microferrogels (MFG). The results for MFGs with different magnetic properties and concentrations of magnetic filler nanoparticles are analysed to detect the transition between non-aggregated configurations and the states with pronounced chains. The nanoparticles are assumed to be either magnetically isotropic or to possess infinite magnetic anisotropy. It is shown that, depending on the type of the particle anisotropy, an applied field in rather different ways affects the MFG structure and shape. Diagrams describing the degree of aggregation as a function of the parameter of the interparticle magnetodipolar interaction and concentration are presented. In particular, it is found that in the case of infinitely anisotropic nanoparticles the aggregation transitions undergoes via a non-trivial scenario. The effect of the structure transformations on the volume change of the MFG objects is studied as well.

    11. EFFECTS OF FLUNIXIN MEGLUMINE CONJUNCTIVAL SHOT OVER THE HUMOR AQUEOUS PROTEIN OF DOGS SUBMITTED TO THE PARACENTESIS OF THE ANTERIOR CHAMBER AVALIAÇÃO DOS EFEITOS DA FLUNIXINA MEGLUMINA, POR VIA SUBCONJUNTIVAL, SOBRE A CONCENTRAÇÃO E PADRÃO PROTEICO DO HUMOR AQUOSO DE CÃES SUBMETIDOS À PARACENTESE DA CÂMARA ANTERIOR

      Directory of Open Access Journals (Sweden)

      Paula Diniz Galera

      2009-12-01

      Full Text Available <div>Flunixin meglumine effects, over aqueous humor proteins of eyes on dogs who were submitted to paracentesis of the anterior chamber, were evaluated. To ten adult dogs clinically healthy were given a subconjunctival shot with flunixin meglumine (1.1mg/Kg on the right eye and sterilized saline solution 0.9% on the left eye, with the same volume. After general anesthesia, were submitted to two paracentesis of the both eyes to collect 0.2mL of first and second aqueous. The samples were submitted to Bradford test, wich proteins concentrations were  15.98mg/dL ± 4.48 e 11.46mg/dL ± 2.72 for the right and the left eyes, respectively, on the first paracentesis and 119.8mg/dL ± 6.74 e 120.63mg/dL ± 22.4 for the right and the left eyes, on the second paracentesis. There was no significant statistically differences between the protein values of the treated eyes in comparison with the control one. When compared, the proteins concentrations between the first and second paracentesis of the right and left eyes, statistic differences were found between these two moments (p<0.001. SDS-PAGE showed differences in the protein patterns of aqueous humor in result of the paracentesis.div>>
      div>>KEY WORDS: Aqueous humor, eye, flunixin meglumine, paracentesis, proteíns.div>>
      div> <div>Avaliaram-se os efeitos da flunixina meglumina, pela via subconjuntival, sobre as proteínas do humor aquoso de olhos de cães submetidos à paracentese da câmara anterior. Dez animais adultos, clinicamente sadios, receberam, por aplicação subconjuntival, flunixina meglumina (1,1mg/kg no olho direito e solução salina estéril a 0,9% no olho esquerdo, em igual volume. Mediante anestesia geral, foram submetidos a duas paracenteses de ambos os olhos para coleta de 0,2mL de aquoso primário e secundário, respectivamente. As amostras foram submetidas ao Teste de Bradford, cujas concentrações proteicas (média e desvio-padrão obtidas foram de 15

    12. BREEDING SOUNDNESS EVALUATION OF TWO AND THREE YEAR OLD NELORE (BOS TAURUS INDICUS BULLS, RAISED UNDER PASTURE CONDITION CLASSIFICAÇÃO ANDROLÓGICA POR PONTOS (CAP DE TOUROS NELORE (Bos taurus indicus DE DOIS E TRÊS ANOS DE IDADE, CRIADOS SOB PASTEJO

      Directory of Open Access Journals (Sweden)

      Juliano Cesar Dias

      2009-12-01

      Full Text Available <div>Data from 583 Nelore bulls, aging from two and three years old, raised under pasture condition, were used to study andrologic traits (physical aspects: motility and vigor; and morphologic: major and total defects of the semen and testicular measurements (scrotal circumference - SC and testicular volume - TVOL to establish a profile of andrologic classification for fertility (BSE. The animals were divided in two groups: young bulls (N = 345, with ages from 18 to 30 months (2 years old, and adult (N = 238, with ages from 31 to 42 months (3 years old. Differences were observed (p < 0.05 for body weight, SC, physical and morphologic characteristics of the semen and TVOL in the two year olds with BSE above and below 60 points. In the three years old bulls differences were observed (p < 0.05 for SC and physical and morphologic characteristics of the semen in bulls with BSE above and below 60 points. The results suggested that body weight and SC affected the reproductive condition of young Nelore bulls. SC and seminal traits were the determining factors in the selection for a better reproductive condition, showing the importance of semen analysis when evaluating bulls raised under pasture conditions.div>>
      div>>KEY WORDS: Andrology, breeding soundness evaluation, scrotal circumference, semen, zebu. div>>
      div> <div>Avaliaram-se 583 touros Nelore, de dois e três anos de idade, criados extensivamente, para estudar as características andrológicas (aspectos físicos: motilidade e vigor espermáticos; e morfológicos: defeitos espermáticos maiores e totais e de biometria testicular (circunferência escrotal – CE – e volume testicular – VOLT, permitindo classificá-los andrologicamente por pontos e estabelecer parâmetros andrológicos. Os animais foram divididos em dois grupos: touros jovens (N = 345, com idades de 18 a 30 meses (2 anos, e adultos (N = 238, com idades de 31 a 42 meses (3 anos. Observaram

    13. Wild kernels for higher K-theory of division and semi-simple algebras

      International Nuclear Information System (INIS)

      Quo Xuejun; Kuku, Aderemi

      2003-06-01

      Let Σ be a semi-simple algebra over a number field F. In this paper, we prove that for all n ≥ 0, the wild kernel WK n (Σ):Ker(K n (Σ) → Π finiteυ K n (Σ υ )) is contained in the torsion part of the image of the natural homomorphism K n (Λ) → K n (Σ), where Λ is a maximal order in Σ. In particular, WK n (Σ) is finite. In the process, we prove that if Λ is a maximal order in a central division algebra D over F, then the kernel of the reduction map K 2n-1 (Λ) → π υ Π finiteυ K 2n-1 (d υ ) is finite. In paragraph 3 we investigate the connections between WK n (D) and div(K n (D)) and prove that divK 2 (Σ) is a subset of WK 2 (Σ); if the index of D is square free, then div(K 2 (D)) ≅ div(K 2 (F)), WK 2 (F) ≅ WK 2 (D) and vertical bar WK 2 (D)/div(K 2 (D)) vertical bar ≤ 2. Finally we prove that if D is a central division algebra over F with [D : F] = m 2 , then (1) div(K n (D)) l = WK n (D) l for all odd primes I and n ≤ 2; (2) if I does not divide m, then div(K 3 (D)) l = WK 3 (D) l = 0; (3) if F = Q and I does not divide m, then div(K n (D)) l is a subset of WK n (D) l for all n. (author)

    14. Aparência tomográfica dos discos intervertebrais mineralizados em cães da raça Dachshund Miniatura

      Directory of Open Access Journals (Sweden)

      D. Baraúna Júnior

      Full Text Available RESUMO Objetivou-se com este trabalho descrever os aspectos de tomografia computadorizada de discos intervertebrais de cães da raça Dachshund com um ano de idade, assim como quantificar, qualificar e localizar a mineralização nos componentes do DIV e no espaço intervertebral da coluna vertebral. Dez cães dessa raça, com um ano de idade, foram submetidos à tomografia computadorizada (TC. Nas imagens de reconstrução sagital dos animais, procedeu-se à identificação de sete DIV em cada animal, entre as vértebras T9 e L3, totalizando a análise de 70 DIV. Entre os DIV mineralizados, a presença da alteração foi determinada quanto à localização no núcleo pulposo (NP, no anel fibroso (AF e em AF/NP. Dos 70 DIV avaliados, 45 foram considerados como mineralizados. Entre os classificados como mineralizados, 20% (9/45, 17,8% (8/45 e 62,2% (28/45 estavam localizados nas regiões do NP, AF e AF/NP, respectivamente. A mineralização encontrada neste estudo esteve caracterizada por aumento de atenuação radiográfica com densidade mineral na topografia do DIV, havendo variações da localização e da radiodensidade de área calcificada entre animais e DIV no mesmo indivíduo. As alterações relativas à mineralização dos DIV podem ser classificadas tomograficamente quanto à localização da alteração no disco em AF, NP e AF/NP.

    15. Analysis of HIV using a high resolution melting (HRM) diversity assay: automation of HRM data analysis enhances the utility of the assay for analysis of HIV incidence.

      Science.gov (United States)

      Cousins, Matthew M; Swan, David; Magaret, Craig A; Hoover, Donald R; Eshleman, Susan H

      2012-01-01

      HIV diversity may be a useful biomarker for discriminating between recent and non-recent HIV infection. The high resolution melting (HRM) diversity assay was developed to quantify HIV diversity in viral populations without sequencing. In this assay, HIV diversity is expressed as a single numeric HRM score that represents the width of a melting peak. HRM scores are highly associated with diversity measures obtained with next generation sequencing. In this report, a software package, the HRM Diversity Assay Analysis Tool (DivMelt), was developed to automate calculation of HRM scores from melting curve data. DivMelt uses computational algorithms to calculate HRM scores by identifying the start (T1) and end (T2) melting temperatures for a DNA sample and subtracting them (T2 - T1 =  HRM score). DivMelt contains many user-supplied analysis parameters to allow analyses to be tailored to different contexts. DivMelt analysis options were optimized to discriminate between recent and non-recent HIV infection and to maximize HRM score reproducibility. HRM scores calculated using DivMelt were compared to HRM scores obtained using a manual method that is based on visual inspection of DNA melting curves. HRM scores generated with DivMelt agreed with manually generated HRM scores obtained from the same DNA melting data. Optimal parameters for discriminating between recent and non-recent HIV infection were identified. DivMelt provided greater discrimination between recent and non-recent HIV infection than the manual method. DivMelt provides a rapid, accurate method of determining HRM scores from melting curve data, facilitating use of the HRM diversity assay for large-scale studies.

    16. Dissociation between the activity of the right middle frontal gyrus and the middle temporal gyrus in processing semantic priming.

      Science.gov (United States)

      Laufer, Ilan; Negishi, Michiro; Lacadie, Cheryl M; Papademetris, Xenophon; Constable, R Todd

      2011-01-01

      The aim of this event-related functional magnetic resonance imaging (fMRI) study was to test whether the right middle frontal gyrus (MFG) and middle temporal gyrus (MTG) would show differential sensitivity to the effect of prime-target association strength on repetition priming. In the experimental condition (RP), the target occurred after repetitive presentation of the prime within an oddball design. In the control condition (CTR), the target followed a single presentation of the prime with equal probability of the target as in RP. To manipulate semantic overlap between the prime and the target both conditions (RP and CTR) employed either the onomatopoeia "oink" as the prime and the referent "pig" as the target (OP) or vice-versa (PO) since semantic overlap was previously shown to be greater in OP. The results showed that the left MTG was sensitive to release of adaptation while both the right MTG and MFG were sensitive to sequence regularity extraction and its verification. However, dissociated activity between OP and PO was revealed in RP only in the right MFG. Specifically, target "pig" (OP) and the physically equivalent target in CTR elicited comparable deactivations whereas target "oink" (PO) elicited less inhibited response in RP than in CTR. This interaction in the right MFG was explained by integrating these effects into a competition model between perceptual and conceptual effects in priming processing.

    17. Acute neuropharmacological effects of atomoxetine on inhibitory control in ADHD children: A fNIRS study

      Directory of Open Access Journals (Sweden)

      Masako Nagashima

      2014-01-01

      Full Text Available The object of the current study is to explore the neural substrate for effects of atomoxetine (ATX on inhibitory control in school-aged children with attention deficit hyperactivity disorder (ADHD using functional near-infrared spectroscopy (fNIRS. We monitored the oxy-hemoglobin signal changes of sixteen ADHD children (6–14 years old performing a go/no-go task before and 1.5 h after ATX or placebo administration, in a randomized, double-blind, placebo-controlled, crossover design. Sixteen age- and gender-matched normal controls without ATX administration were also monitored. In the control subjects, the go/no-go task recruited the right inferior and middle prefrontal gyri (IFG/MFG, and this activation was absent in pre-medicated ADHD children. The reduction of right IFG/MFG activation was acutely normalized after ATX administration but not placebo administration in ADHD children. These results are reminiscent of the neuropharmacological effects of methylphenidate to up-regulate reduced right IFG/MFG function in ADHD children during inhibitory tasks. As with methylphenidate, activation in the IFG/MFG could serve as an objective neuro-functional biomarker to indicate the effects of ATX on inhibitory control in ADHD children. This promising technique will enhance early clinical diagnosis and treatment of ADHD in children, especially in those with a hyperactivity/impulsivity phenotype.

    18. Dissociation between the activity of the right middle frontal gyrus and the middle temporal gyrus in processing semantic priming.

      Directory of Open Access Journals (Sweden)

      Ilan Laufer

      Full Text Available The aim of this event-related functional magnetic resonance imaging (fMRI study was to test whether the right middle frontal gyrus (MFG and middle temporal gyrus (MTG would show differential sensitivity to the effect of prime-target association strength on repetition priming. In the experimental condition (RP, the target occurred after repetitive presentation of the prime within an oddball design. In the control condition (CTR, the target followed a single presentation of the prime with equal probability of the target as in RP. To manipulate semantic overlap between the prime and the target both conditions (RP and CTR employed either the onomatopoeia "oink" as the prime and the referent "pig" as the target (OP or vice-versa (PO since semantic overlap was previously shown to be greater in OP. The results showed that the left MTG was sensitive to release of adaptation while both the right MTG and MFG were sensitive to sequence regularity extraction and its verification. However, dissociated activity between OP and PO was revealed in RP only in the right MFG. Specifically, target "pig" (OP and the physically equivalent target in CTR elicited comparable deactivations whereas target "oink" (PO elicited less inhibited response in RP than in CTR. This interaction in the right MFG was explained by integrating these effects into a competition model between perceptual and conceptual effects in priming processing.

    19. The role of locus of control, self-esteem, parenting style, loneliness, and academic achievement in predicting bullying among middle school students

      OpenAIRE

      ATİK, Gökhan

      2006-01-01

      <div class="page" title="Page 4"><div class="layoutArea"><div class="column">

      This study aimed at determining the prevalence rate of bullying and victimization among middle school students and investigating the role of locus of control, self- esteem, parenting style, loneliness, and academic achievement in predicting participation in bullying and victimization. The sample consisted of 742 participants recruited from 6th

    20. ALTERAÇÕES HEMATOLÓGICAS DURANTE A IMUNIZAÇÃO E APÓS A SANGRIA E PLASMAFERESE EM EQUINOS DE PRODUÇÃO DE SORO HIPERIMUNE ANTICROTÁLICO HAEMATOLOGY CHANGES DURING THE IMMUNIZATION AND AFTER THE BLEEDING AND PHASMAFERESE IN HORSES USED FOR HYPERIMUNE ANTI-CROTALIC SERUM PRODUCTION

      Directory of Open Access Journals (Sweden)

      Ronaldo Azevedo Ferreira

      2009-12-01

      Full Text Available <div>Para o estabelecimento do quadro sanguíneo de equinos durante a imunização para produção de soro hiperimune anticrotálico e após as sangrias de produção e a plasmaferese, realizou-se avaliação hematológica para determinar a eficácia da plasmaferese na recuperação do quadro hematimétrico dos animais. Foram utilizados vinte animais, submetidos às normas do protocolo de imunização do Instituto Butantan, sendo  colhidas amostras antes das inoculações do antígeno (veneno crotálico, antes e depois das sangrias de produção, após as plasmafereses e quinze, trinta e quarenta e cinco dias após a última sangria, totalizando 340 colheitas, realizadas em dezessete momentos, para realização do hemograma. Significativas variações no quadro hematológico dos equinos foram observadas na fase de imunização, caracterizando anemia normocítica normocrômica, sem alterações significativas do leucograma. Nas fases de sangrias, observaram-se evidentes variações no quadro hematológico, demonstrando uma anemia normocítica normocrômica pós-sangrias, sem variações nos valores do leucograma. No período de repouso, foi evidente a eficácia da plasmaferese, com pronta, mas parcial, recuperação do hemograma, facilitando o rápido retorno para normalidade hematológica, tornando-os aptos à nova produção de soro hiperimune.div>>
      div>>PALAVRAS-CHAVES: Anticrotálico, equinos, hematologia, imunização, plasmaferese.div>>
      div> <div>Twenty animals were used to assess the blood profile of horses during immunization for anticrotalic hyperimmune serum production and after the bleedings and the plasmapherese, according to the protocol schedule of Instituto Butantan in order to evaluate efficacy of plasmapheresis. The samples were obtained before the antigen inoculations (crotalic venon, before and after the bleedings, right after the plasmapherese and 15, 30 and 45 days after the last one, making a

    1. Integrating personality structure, personality process, and personality development

      NARCIS (Netherlands)

      Baumert, Anna; Schmitt, Manfred; Perugini, Marco; Johnson, Wendy; Blum, Gabriela; Borkenau, Peter; Costantini, Giulio; Denissen, J.J.A.; Fleeson, William; Grafton, Ben; Jayawickreme, Eranda; Kurzius, Elena; MacLeod, Colin; Miller, Lynn C.; Read, Stephen J.; Robinson, Michael D.; Wood, Dustin; Wrzus, Cornelia

      2017-01-01

      In this target article, we argue that personality processes, personality structure, and personality development have to be understood and investigated in integrated ways in order to provide comprehensive responses to the key questions of personality psychology. The psychological processes and

    2. CRIOPRESERVAÇÃO DE SÊMEN CANINO COM UM DILUIDOR À BASE DE ÁGUA DE COCO NA FORMA DE PÓ (ACP-106®: EFEITO DA TEMPERATURA DE ADIÇÃO DO GLICEROL (27 E 4°C CRYOPRESERVATION CANINE SEMEN USING A POWDERED COCONUT WATER EXTENDER (APC-106: EFFECT OF GLYCEROL TEMPERATURE ADDITION (27OC AND 4OC

      Directory of Open Access Journals (Sweden)

      Daniel Couto Uchoa

      2009-12-01

      Full Text Available <div>Objetivou-se comparar o efeito da temperatura de adição do glicerol sobre o sêmen canino diluído em água de coco na forma de pó (ACP-106® e criopreservado. Coletaram-se doze ejaculados, para avaliação da fração espermática, dividida em duas alíquotas. A primeira foi diluída em ACP-106® com 5% de gema de ovo e 6% de glicerol a 27°C (G27 e a segunda em ACP-106® com 5% de gema de ovo, com a glicerolização a 4°C (G4. As amostras foram congeladas, posteriormente, descongeladas e submetidas às avaliações de morfologia, integridade acrossomal, teste hipo-osmótico e percentual de vivos. Não se observou diferença entre as temperaturas de adição do glicerol em todos os parâmetros. Na análise computadorizada, também não se evidenciou diferença entre os grupos na motilidade total e progressiva, percentual de espermatozoides com velocidade rápida e média, e velocidade média da trajetória (VAP dos espermatozoides com velocidade rápida e média, sendo observadas, em G4 e G27, respectivamente, uma motilidade total de 24,45 ± 3,93% e 31,65 ± 3,87% e VAP dos espermatozoides rápidos de 91,24 ± 7,74µm/s e 106,25 ± 3,94µm/s. Conclui-se que a temperatura de adição do glicerol não influencia a qualidade pós-descongelação do sêmen canino diluído em ACP-106®.div>>
      div>>PALAVRAS-CHAVES: ACP-106®, cão, criopreservação, glicerol, sêmen. div>>
      div> The aim of the present study was to compare the effect of glycerol addition at two temperatures on canine semen extended and frozen with powdered coconut water extender (ACP-106®. Twelve ejaculates were collected, the sperm-rich fraction was evaluated and further divided into two aliquots. The first aliquot was extended in ACP-106® with 5% egg yolk and glycerol at 27ºC (G27 and the second one was also extended in ACP-106® with 5% egg yolk, with glycerol addition at 4ºC (G4. Samples were frozen, thawed and submitted to evaluations

    3. Monotone numerical methods for finite-state mean-field games

      KAUST Repository

      Gomes, Diogo A.; Saude, Joao

      2017-01-01

      Here, we develop numerical methods for finite-state mean-field games (MFGs) that satisfy a monotonicity condition. MFGs are determined by a system of differential equations with initial and terminal boundary conditions. These non-standard conditions are the main difficulty in the numerical approximation of solutions. Using the monotonicity condition, we build a flow that is a contraction and whose fixed points solve the MFG, both for stationary and time-dependent problems. We illustrate our methods in a MFG modeling the paradigm-shift problem.

    4. Monotone numerical methods for finite-state mean-field games

      KAUST Repository

      Gomes, Diogo A.

      2017-04-29

      Here, we develop numerical methods for finite-state mean-field games (MFGs) that satisfy a monotonicity condition. MFGs are determined by a system of differential equations with initial and terminal boundary conditions. These non-standard conditions are the main difficulty in the numerical approximation of solutions. Using the monotonicity condition, we build a flow that is a contraction and whose fixed points solve the MFG, both for stationary and time-dependent problems. We illustrate our methods in a MFG modeling the paradigm-shift problem.

    5. USE OF DIFFERENT SODIUM SOURCES ON BROILER PERFORMANCE AND LITTER HUMIDITY USO DE DIFERENTES FONTES DE SÓDIO NA DIETA DE FRANGOS DE CORTE DE 22 A 42 DIAS DE IDADE SOBRE O DESEMPENHO E UMIDADE DA CAMA

      Directory of Open Access Journals (Sweden)

      Débora Cristina Nichelle Lopes

      2009-12-01

      Full Text Available A total of 552 female Ross broiler chicks were fed diets containing  3  different sodium sources (sodium chloride, sodium bicarbonate and sodium formiate, with or without addition of ammonium chloride from 22 to 42 days of age. Performance and litter moisture content were evaluated. Feed and water were supplied ad libitum. A complete  experimental block design was used. Birds were distributed into 4 treatments with 6 replicates each. Each one of the replicates contained 23 birds. Each body weight, weight gain, feed intake, feed conversion, the european effciency factor and litter moisture content were examined. Experimental data was analyzed  using ANOVA. When a significant F test was obtained, means were separated using Tukey test. A probability of 0.05 was required for statements of significance. Results indicated that sodium bicarbonate and sodium formiate did not influence broiler growth performance, however a hight litter moisture content was observed in birds fed diets containing sodium bicarbonate. Furthermore, the addition of amonium chloride to the diet containing sodium formiate did not influence broiler growth performance and litter moisture. <div>
      div>>Key words: Electrolyte balance, excreta, sodium bicarbonate, sodium formiate. div> <div>Foram utilizadas 552 fêmeas de corte, da linhagem Ross, no período de 22 a 42 dias de idade, com o objetivo de avaliar os efeitos de três fontes de sódio (Na+ na dieta sobre o desempenho das aves e também sobre a umidade da cama. As aves receberam ração e água ad libitum. O delineamento experimental utilizado foi o de blocos ao acaso, com quatro tratamentos e seis repetições, sendo a unidade experimental representada pelo boxe com 23 aves. Utilizaram-se como fontes de sódio o cloreto de sódio, o bicarbonato de sódio e o formiato de sódio, com ou sem adição de fonte de cloro (cloreto de amônia. As variáveis analisadas foram: consumo de ração, ganho de peso

    6. Direct estimation of human trabecular bone stiffness using cone beam computed tomography.

      Science.gov (United States)

      Klintström, Eva; Klintström, Benjamin; Pahr, Dieter; Brismar, Torkel B; Smedby, Örjan; Moreno, Rodrigo

      2018-04-10

      The aim of this study was to evaluate the possibility of estimating the biomechanical properties of trabecular bone through finite element simulations by using dental cone beam computed tomography data. Fourteen human radius specimens were scanned in 3 cone beam computed tomography devices: 3-D Accuitomo 80 (J. Morita MFG., Kyoto, Japan), NewTom 5 G (QR Verona, Verona, Italy), and Verity (Planmed, Helsinki, Finland). The imaging data were segmented by using 2 different methods. Stiffness (Young modulus), shear moduli, and the size and shape of the stiffness tensor were studied. Corresponding evaluations by using micro-CT were regarded as the reference standard. The 3-D Accuitomo 80 (J. Morita MFG., Kyoto, Japan) showed good performance in estimating stiffness and shear moduli but was sensitive to the choice of segmentation method. NewTom 5 G (QR Verona, Verona, Italy) and Verity (Planmed, Helsinki, Finland) yielded good correlations, but they were not as strong as Accuitomo 80 (J. Morita MFG., Kyoto, Japan). The cone beam computed tomography devices overestimated both stiffness and shear compared with the micro-CT estimations. Finite element-based calculations of biomechanics from cone beam computed tomography data are feasible, with strong correlations for the Accuitomo 80 scanner (J. Morita MFG., Kyoto, Japan) combined with an appropriate segmentation method. Such measurements might be useful for predicting implant survival by in vivo estimations of bone properties. Copyright © 2018 Elsevier Inc. All rights reserved.

    7. MRI-based flow measurements in the main pulmonary artery to detect pulmonary arterial hypertension in patients with cystic fibrosis; MRT-basierte Flussmessungen im Truncus pulmonalis zur Detektion einer pulmonal-arteriellen Hypertonie in Patienten mit zystischer Fibrose

      Energy Technology Data Exchange (ETDEWEB)

      Wolf, T.; Anjorin, A.; Abolmaali, N. [TU Dresden (Germany). OncoRay, Biologisches und Molekulares Imaging; Posselt, H. [Frankfurt Univ. (Germany). Klinik fuer Paediatrie I, Muskoviszidoseambulanz; Smaczny, C. [Frankfurt Univ. (Germany). Medizinische Klinik I, Pneumologie und Allergologie; Vogl, T.J. [Frankfurt Univ. (Germany). Inst. fuer Diagnostische und Interventionelle Radiologie

      2009-02-15

      Development of pulmonary arterial hypertension (PH) is a common problem in the course of patients suffering from cystic fibrosis (CF). This study was performed to evaluate MRI based flow measurements (MR{sub venc}; Velocity ENCoding) to detect signs of an evolving PH in patients suffering from CF. 48 patients (median age: 16 years, range: 10 - 40 years, 25 female) suffering from CF of different severity (mean FEV1: 74 % {+-} 23, mean Shwachman-score: 63 {+-} 10) were examined using MRI based flow measurements of the main pulmonary artery (MPA). Phase-contrast flash sequences (TR: 9.6 ms, TE: 2.5 ms, bandwidth: 1395 Hertz/Pixel) were utilized. Results were compared to an age- and sex-matched group of 48 healthy subjects. Analyzed flow data where: heart frequency (HF), cardiac output (HZV), acceleration time (AT), proportional acceleration time related to heart rate (ATr), mean systolic blood velocity (MFG), peak velocity (Peak), maximum flow (Fluss{sub max}), mean flow (Fluss{sub mitt}) and distensibility (Dist). The comparison of means revealed significant differences only for MFG, Fluss{sub max} and Dist, but overlap was marked. However, using a scatter-plot of AT versus MFG, it was possible to identify five CF-patients demonstrating definite signs of PH: AT = 81 ms {+-} 14, MFG = 46 {+-} 11 cm/s, Dist = 41 % {+-} 7. These CF-patients where the most severely affected in the investigated group, two of them were listed for complete heart and lung transplantation. The comparison of this subgroup and the remaining CF-patients revealed a highly significant difference for the AT (p = 0.000001) without overlap. Screening of CF-patients for the development of PH using MR{sub venc} of the MPA is not possible. In later stages of disease, the quantification of AT, MFG and Dist in the MPA may be useful for the detection, follow-up and control of therapy of PH. MR{sub venc} of the MPA completes the MRI-based follow-up of lung parenchyma damage in patients suffering from CF

    8. MRI-based flow measurements in the main pulmonary artery to detect pulmonary arterial hypertension in patients with cystic fibrosis

      International Nuclear Information System (INIS)

      Wolf, T.; Anjorin, A.; Abolmaali, N.; Posselt, H.; Smaczny, C.; Vogl, T.J.

      2009-01-01

      Development of pulmonary arterial hypertension (PH) is a common problem in the course of patients suffering from cystic fibrosis (CF). This study was performed to evaluate MRI based flow measurements (MR venc ; Velocity ENCoding) to detect signs of an evolving PH in patients suffering from CF. 48 patients (median age: 16 years, range: 10 - 40 years, 25 female) suffering from CF of different severity (mean FEV1: 74 % ± 23, mean Shwachman-score: 63 ± 10) were examined using MRI based flow measurements of the main pulmonary artery (MPA). Phase-contrast flash sequences (TR: 9.6 ms, TE: 2.5 ms, bandwidth: 1395 Hertz/Pixel) were utilized. Results were compared to an age- and sex-matched group of 48 healthy subjects. Analyzed flow data where: heart frequency (HF), cardiac output (HZV), acceleration time (AT), proportional acceleration time related to heart rate (ATr), mean systolic blood velocity (MFG), peak velocity (Peak), maximum flow (Fluss max ), mean flow (Fluss mitt ) and distensibility (Dist). The comparison of means revealed significant differences only for MFG, Fluss max and Dist, but overlap was marked. However, using a scatter-plot of AT versus MFG, it was possible to identify five CF-patients demonstrating definite signs of PH: AT = 81 ms ± 14, MFG = 46 ± 11 cm/s, Dist = 41 % ± 7. These CF-patients where the most severely affected in the investigated group, two of them were listed for complete heart and lung transplantation. The comparison of this subgroup and the remaining CF-patients revealed a highly significant difference for the AT (p = 0.000001) without overlap. Screening of CF-patients for the development of PH using MR venc of the MPA is not possible. In later stages of disease, the quantification of AT, MFG and Dist in the MPA may be useful for the detection, follow-up and control of therapy of PH. MR venc of the MPA completes the MRI-based follow-up of lung parenchyma damage in patients suffering from CF. (orig.)

    9. The More the Merrier? The Effects of Type of Cultural Diversity on Exclusionary Immigration Attitudes in Switzerland

      Directory of Open Access Journals (Sweden)

      Eva G. T. Green

      2010-12-01

      Full Text Available <div>We investigate how different types of cultural diversity influence anti-immigration attitudes across Swiss municipalities. While from a threat theory perspective,div>>a high number of immigrants within a region increases (perceived threat which fosters negative immigration attitudes, intergroup contact theory contends that culturally diverse societal contexts increase opportunities for contacts with immigrants, which give rise to more positive immigration attitudes. Prior research on ethnic hierarchies and host society acculturation attitudes led us to hypothesize that the presence of valued, “culturally similar” immigrants from wealthier countries increases contact and decreases threat, thereby reducing anti-immigrant prejudice. The presence of devalued, “culturally distant” immigrants from poorer countries should increase threat perceptions and dissuade contact thus heightening prejudice. A multilevel studydiv>>was conducted using the 2002 European Social Survey (N = 1472 Swiss citizens, N = 185 municipalities. Replicating previous research, contact reduced exclusionary immigration attitudes through reduced threat. On the municipality level, higher proportion of North and West European immigrants increased contact, thus reducing threat. A larger proportion of Muslims was related to an increase in threat, leading to more pronounced exclusionary attitudes, but also to increased contact. Finally, we discuss how the impact of diversity depends on the social construction of immigrant categories, respondents’ social position and ideological stances, and the prevailing local ideological climate.div>

    10. DNA-mediated dimerization on a compact sequence signature controls enhancer engagement and regulation by FOXA1.

      Science.gov (United States)

      Wang, Xuecong; Srivastava, Yogesh; Jankowski, Aleksander; Malik, Vikas; Wei, Yuanjie; Del Rosario, Ricardo C H; Cojocaru, Vlad; Prabhakar, Shyam; Jauch, Ralf

      2018-04-14

      FOXA1 is a transcription factor capable to bind silenced chromatin to direct context-dependent cell fate conversion. Here, we demonstrate that a compact palindromic DNA element (termed 'DIV' for its diverging half-sites) induces the homodimerization of FOXA1 with strongly positive cooperativity. Alternative structural models are consistent with either an indirect DNA-mediated cooperativity or a direct protein-protein interaction. The cooperative homodimer formation is strictly constrained by precise half-site spacing. Re-analysis of chromatin immunoprecipitation sequencing data indicates that the DIV is effectively targeted by FOXA1 in the context of chromatin. Reporter assays show that FOXA1-dependent transcriptional activity declines when homodimeric binding is disrupted. In response to phosphatidylinositol-3 kinase inhibition DIV sites pre-bound by FOXA1 such as at the PVT1/MYC locus exhibit a strong increase in accessibility suggesting a role of the DIV configuration in the chromatin closed-open dynamics. Moreover, several disease-associated single nucleotide polymorphisms map to DIV elements and show allelic differences in FOXA1 homodimerization, reporter gene expression and are annotated as quantitative trait loci. This includes the rs541455835 variant at the MAPT locus encoding the Tau protein associated with Parkinson's disease. Collectively, the DIV guides chromatin engagement and regulation by FOXA1 and its perturbation could be linked to disease etiologies.

    11. Novo-desenvolvimento, capital social e desigualdade social

      Directory of Open Access Journals (Sweden)

      Ana Cristina de Oliveira Oliveira

      2012-03-01

      Full Text Available Este artigo aborda a tendência de enfrentamento da desigualdade social a partir, no campo econômico, da versão do novo-desenvolvimentismo e, no campo político e ideológico, a partir da noção de capital social, na tentativa de realizar um "capitalismo com face mais humana". Discutiremos duas ordens de questões, considerando a especificidade da formação social brasileira de capitalismo dependente: 1 a “construção de Estados fortes” para<div>assegurar as condições de acumulação do capital, ampliando as margens do mercado de consumo, aliviando a pobreza e controlando possíveis tensões políticas e 2 a difusão da necessidade de construir uma sociedade em harmonia, que se traduz na incorporação da ética empreendedora dos empresários em todas as esferas sociais. Entendemos que este escopo político-econômico revela uma nova pedagogia da hegemonia, sustentada numa suposta alternativadiv>>de gerenciamento das novas expressões da “questão social”, voltada para educar o conformismo e ocultar o conflito de classes.div>>Palavras-chave:  questão social; novo-desenvolvimentismo; capital social; inclusão forçadadiv>

    12. Design information verification for spent fuel conditioning plants and for geological repositories

      International Nuclear Information System (INIS)

      Myatt, J.; Ward, M.D.

      1995-01-01

      The disposal of spent fuel is a major option for the back-end of the nuclear fuel cycle. It will require the construction, operation and eventual closure of conditioning plants and geological repositories. Consequently, a safeguards approach including Design Information Verification (DIV) must be developed for these facilities. DIV Is the examination of a completed facility to verify that it has been built to the design declared by the operator. Although DIV takes place chiefly before a plant begins routine operation, there is a continuing interest in ensuring that the plant remains as declared. That is, that the continuity of knowledge of design information is maintained during the operational phase of the plant and also post closure if necessary. A major problem with DIV of a repository is that there will be continuous structural changes during its operational life requiring advanced or special techniques for reverification. Some of these are briefly reviewed. Furthermore, since a disposal facility is expected to be operational for several decades, new mining technology may also have an impact on the DIV methods employed. Another factor in the safeguards supervision of a repository is that when the fuel has been backfilled and/or scaled in place a reassay will be a very costly exercise. The role of DIV in such novel circumstances must, therefore, be fully considered

    13. Domain IV voltage-sensor movement is both sufficient and rate limiting for fast inactivation in sodium channels.

      Science.gov (United States)

      Capes, Deborah L; Goldschen-Ohm, Marcel P; Arcisio-Miranda, Manoel; Bezanilla, Francisco; Chanda, Baron

      2013-08-01

      Voltage-gated sodium channels are critical for the generation and propagation of electrical signals in most excitable cells. Activation of Na(+) channels initiates an action potential, and fast inactivation facilitates repolarization of the membrane by the outward K(+) current. Fast inactivation is also the main determinant of the refractory period between successive electrical impulses. Although the voltage sensor of domain IV (DIV) has been implicated in fast inactivation, it remains unclear whether the activation of DIV alone is sufficient for fast inactivation to occur. Here, we functionally neutralize each specific voltage sensor by mutating several critical arginines in the S4 segment to glutamines. We assess the individual role of each voltage-sensing domain in the voltage dependence and kinetics of fast inactivation upon its specific inhibition. We show that movement of the DIV voltage sensor is the rate-limiting step for both development and recovery from fast inactivation. Our data suggest that activation of the DIV voltage sensor alone is sufficient for fast inactivation to occur, and that activation of DIV before channel opening is the molecular mechanism for closed-state inactivation. We propose a kinetic model of sodium channel gating that can account for our major findings over a wide voltage range by postulating that DIV movement is both necessary and sufficient for fast inactivation.

    14. Fatty acid composition of commercially available Iranian edible oils

      Directory of Open Access Journals (Sweden)

      Sedigheh Asgary

      2009-08-01

      Full Text Available

      • <div align="left">BACKGROUND: Trans-fatty acids (TFAs, unsaturated fats with at least one double bond in the Trans configuration, are industrially formed in large quantities when vegetable oils are partially hydrogenated. This study was  ndertaken to quantify the amounts of the common fatty acids in several commercial oils marketing in Iran.div>
      • <div align="left">METHODS: The most consumed commercially available brands of vegetable oils were randomly selected from products available in supermarkets. A 10g sample was drawn from each mixed sample and prepared for fatty cid analysis by gas chromatography (GC.div>
      • <div align="left">RESULTS: Palmitic acid (C16:0 and stearic acid (C18:0 jointly constituted 21% of total fatty acids in partially hydrogenated vegetable oils (PHVOs. More than one third of total fatty acids in Iranian PHVOs were Trans fats. TFAs constituted almost 1% and 3% of total fatty  cids in Iranian cooking and frying oils. This study  howed higher contents of TFAs in Iranian commercially available hydrogenated vegetable oils. Statistical Package for Social Sciences was used for all statistical analyses.div>
      • <div align="left">CONCLUSIONS: Although

      • Effects of Urban Waste and Mineral Fertilizers Applications on Eucalyptus grandis Growth and Soil Conditions Efeito da Aplicação de Lixo Urbano Compostado e de Adubos Minerais no Solo e na Produtividade de Eucalyptus grandis

        Directory of Open Access Journals (Sweden)

        Guilherme de Castro Andrade

        2011-03-01

        Full Text Available <div>Forest plantations have been studied as a potential ecosystem able to absorb organic residues as fertilizers or soil conditioners. This study evaluate the effects of the application of composted organic waste and mineral fertilizers in a Eucalyptus grandis (W. Hill ex Maiden plantation with 86 months of age in Neossolo Quartzarênico. It was analyzed wood production, litter decomposition and the physical and chemical changes in the soil properties. It was observed that the municipal composted organic wastes resulted in an increase of 45.6% in wood volume, as compared to the control. It also increase the velocity of the litterdiv>>decomposition on average of 28% and 16% for leaves and twigs respectively, increasing the pH level values and the availability of water in the soil (from 13% to 25% more available water in the first layer of the soil, 0 -10 cm. div>>As florestas têm sido estudadas como ecossistemas aptos à absorver resíduos orgânicos, utilizados como fertilizantes e condicionadores do solo. Este trabalho avaliou no Município de Itatinga, SP, em Neossolo Quartzarênico, os efeitos da aplicação de lixo urbano compostado e da adubação mineral em plantações de Eucalyptus grandis com 86 meses de idade. Foram analisadas as produtividades de madeira, a decomposição da serapilheira e as propriedades químicas e físicas dodiv>>solo. Verificou-se que a aplicação de lixo urbano aumentou a produtividade de E. grandis com relação à testemunha, com um ganho de 45,6 % no volume cilíndrico de madeira. O solo com aplicação de lixo urbano apresentou um menor tempo de decomposição da serapilheira, em média com reduções de 28 % para folhas e de 16 % para galhos, com aumentos no pH e na água disponível no solo de 13 % a 25 %, na camada de 0 a 10 cm de profundidade, que podem justificar a maiordiv>>produção de madeira obtida no final da rotação, em

      • Trait approach and avoidance motivation: lateralized neural activity associated with executive function.

        Science.gov (United States)

        Spielberg, Jeffrey M; Miller, Gregory A; Engels, Anna S; Herrington, John D; Sutton, Bradley P; Banich, Marie T; Heller, Wendy

        2011-01-01

        Motivation and executive function are both necessary for the completion of goal-directed behavior. Research investigating the manner in which these processes interact is beginning to emerge and has implicated middle frontal gyrus (MFG) as a site of interaction for relevant neural mechanisms. However, this research has focused on state motivation, and it has not examined functional lateralization. The present study examined the impact of trait levels of approach and avoidance motivation on neural processes associated with executive function. Functional magnetic resonance imaging was conducted while participants performed a color-word Stroop task. Analyses identified brain regions in which trait approach and avoidance motivation (measured by questionnaires) moderated activation associated with executive control. Approach was hypothesized to be associated with left-lateralized MFG activation, whereas avoidance was hypothesized to be associated with right-lateralized MFG activation. Results supported both hypotheses. Present findings implicate areas of middle frontal gyrus in top-down control to guide behavior in accordance with motivational goals. Copyright © 2010 Elsevier Inc. All rights reserved.

      • Tri-Service Construction Guide Specifications

        Science.gov (United States)

        1992-04-01

        fna -d So f tit ban A91 bon Sr I ft In Is au p ....... ~C 0 I aV Div IIr~f idw Div I CIp~ DIV I not 3 SWSIYS 0 IV IF Is ehnc a S 1-8 because of...Liquid and Gas Storage Tanks 11120 Vending Equipment 13220 Filter Underdrains and Media 11130 Audio-Visual Equipment 13230 Digester Covers and...Fabrications 05500 CW 8510 05501 Metalwork Fabrication, Machine Work, and Miscellaneous Provisions 05500 CW 8502 05502 Miscellaneous Metal Materials

      • The effect of the Malaysian Food Guideline guidance on a group of overweight and obese women during Ramadan.

        Science.gov (United States)

        Suriani, Ismail; Shamsuddin, Khadijah; Abdul Latif, Khalib; Saad, Hazizi A

        2015-01-01

        To determine the effect of imparting knowledge of the Malaysian Food Guideline (MFG) on a group of overweight and obese women during Ramadan. This intervention study was conducted during the months of Ramadan 2011. A group of 84 Malay Muslim women with a body mass index (BMI) ≥25 kg/m2 were recruited. Prior to Ramadan, the respondents were educated regarding MFG, and how to monitor and record their daily food intake in a food diary. Their quantity of food intake, BMI, blood pressure (BP), blood lipid profile, and fasting blood sugar (FBS) were measured before Ramadan as a baseline. Their quantity of food intake was then measured again in the third week, whereas their BMI, BP, blood lipid profile, and FBS were determined on the fourth week of Ramadan. At baseline, compared with the MFG recommendations, the intake of protein (107.5%), and milk and dairy products (133%) was higher, whereas the intake of carbohydrates (78.5%), and vegetables and fruits (44.4%) was lower. During Ramadan, carbohydrate intake, BMI, high density lipoprotein-cholesterol (HDL-C) and low density lipoprotein-cholesterol (LDL)-C (all p=0.000), triglyceride (p=0.005), and FBS (p=0.002) were reduced, but the TC/HDL-C ratio was increased (p=0.000). A month-long Ramadan fast guided by the knowledge of MFG resulted in certain positive changes in this group of respondents. These changes can be a good start for health improvement, provided that they are followed-up after Ramadan.

      • Charge immobilization of the voltage sensor in domain IV is independent of sodium current inactivation.

        Science.gov (United States)

        Sheets, Michael F; Hanck, Dorothy A

        2005-02-15

        Recovery from fast inactivation in voltage-dependent Na+ channels is associated with a slow component in the time course of gating charge during repolarization (i.e. charge immobilization), which results from the slow movement of the S4 segments in domains III and IV (S4-DIII and S4-DIV). Previous studies have shown that the non-specific removal of fast inactivation by the proteolytic enzyme pronase eliminated charge immobilization, while the specific removal of fast inactivation (by intracellular MTSET modification of a cysteine substituted for the phenylalanine in the IFM motif, ICMMTSET, in the inactivation particle formed by the linker between domains III and IV) only reduced the amount of charge immobilization by nearly one-half. To investigate the molecular origin of the remaining slow component of charge immobilization we studied the human cardiac Na+ channel (hH1a) in which the outermost arginine in the S4-DIV, which contributes approximately 20% to total gating charge (Qmax), was mutated to a cysteine (R1C-DIV). Gating charge could be fully restored in R1C-DIV by exposure to extracellular MTSEA, a positively charged methanethiosulphonate reagent. The RIC-DIV mutation was combined with ICMMTSET to remove fast inactivation, and the gating currents of R1C-DIV-ICM(MTSET) were recorded before and after modification with MTSEAo. Prior to MTSEAo, the time course of the gating charge during repolarization (off-charge) was best described by a single fast time constant. After MTSEA, the off-charge had both fast and slow components, with the slow component accounting for nearly 35% of Qmax. These results demonstrate that the slow movement of the S4-DIV during repolarization is not dependent upon the normal binding of the inactivation particle.

      • Signature of two contracts for the supply of corrector magnets and the hand-over of a Letter of Intent (LoI) referring to the award of a contract for the supply of superconducting quadrupole magnets for the LHC program to company TESLA Engineering Ltd. (UK)

        CERN Multimedia

        Laurent Guiraud

        2000-01-01

        CERN: Dr. K.H. Kissler, Div. Leader SPL, Th. Lagrange, Head of the Purchasing Service, I. Lobmaier, Purchasing Service, A. Ijspeert, LHC Div. TESLA Engineering Ltd (UK): Dr M. Begg, Managing director British delegation at CERN: Dr. Morrell

    1. A mean-field game economic growth model

      KAUST Repository

      Gomes, Diogo A.

      2016-08-05

      Here, we examine a mean-field game (MFG) that models the economic growth of a population of non-cooperative, rational agents. In this MFG, agents are described by two state variables - the capital and consumer goods they own. Each agent seeks to maximize his/her utility by taking into account statistical data about the whole population. The individual actions drive the evolution of the players, and a market-clearing condition determines the relative price of capital and consumer goods. We study the existence and uniqueness of optimal strategies of the agents and develop numerical methods to compute these strategies and the equilibrium price.

    2. Existence of weak solutions to first-order stationary mean-field games with Dirichlet conditions

      KAUST Repository

      Ferreira, Rita; Gomes, Diogo A.; Tada, Teruo

      2018-01-01

      In this paper, we study first-order stationary monotone mean-field games (MFGs) with Dirichlet boundary conditions. While for Hamilton--Jacobi equations Dirichlet conditions may not be satisfied, here, we establish the existence of solutions of MFGs that satisfy those conditions. To construct these solutions, we introduce a monotone regularized problem. Applying Schaefer's fixed-point theorem and using the monotonicity of the MFG, we verify that there exists a unique weak solution to the regularized problem. Finally, we take the limit of the solutions of the regularized problem and using Minty's method, we show the existence of weak solutions to the original MFG.

    3. AMPA receptor mediated excitotoxicity in neocortical neurons is developmentally regulated and dependent upon receptor desensitization

      DEFF Research Database (Denmark)

      Jensen, J B; Schousboe, A; Pickering, D S

      1998-01-01

      with a fast and rapidly desensitizing response, this could explain the relatively low toxicity produced by 500 microM AMPA. This was investigated by blocking AMPA receptor desensitization with cyclothiazide. Using a lower concentration (25 microM) of AMPA, addition of 50 microM cyclothiazide increased...... the AMPA induced excitotoxicity in cultured cortical neurons at all DIV except for DIV 2. This combination of AMPA + cyclothiazide yielded 77% cell death for DIV 12 cultures. In contrast to the results observed with 500 microM AMPA, the neurotoxicity mediated directly by AMPA receptors when desensitization...

    4. DEVELOPMENT OF HAMBURGER USING ADULT SHEEP MEAT AND OAT FLOUR DESENVOLVIMENTO DE HAMBÚRGUER DE CARNE DE OVINOS DE DESCARTE ENRIQUECIDO COM FARINHA DE AVEIA

      Directory of Open Access Journals (Sweden)

      Luís Carlos Oliveira dos Santos Júnior

      2009-12-01

      Full Text Available <div>The purpose of the present study was to produce a hamburger using adult sheep meat – which is not usually well accepted for in natura consumption – and oat flour. Centesimal composition, pH, water activity, color, fatty acid content, water retention capacity and cooking loss (of both adult sheep meat and the burger patty were assessed. Carbohydrates, total calorie content and sensory characteristics of the formulated products were also considered. Adult sheep meat contained 19% of protein, 5.4% of lipids, 1.18% of ashes and 76% of humidity. The meat from adult sheep and that from young animals differed remarkably in terms of lipid content. All other parameters complied with current meat regulations, although the addition of oats and/or pork to the burgers modified the ash and humidity contents. The sensory evaluation revealed that the sample containing 50% of adult sheep meat, 46% of pork and 4% of oats – which represents the maximum content allowed by law for non-meat sources of protein – enjoyed more widespread acceptance. The hamburgers made of adult sheep meat and oat flour were well accepted by the sensory panel and conform to current regulations, being therefore suitable for the manufacture of meat derivatives.div>>
      div>>Key words: Centesimal composition, dietary fiber, sensorial analysis.div> <div>O objetivo deste trabalho foi desenvolver um produto cárneo do tipo hambúrguer, adicionado de farinha de aveia, visando ao aproveitamento da carne de ovinos de descarte, uma matéria-prima de pouca aceitação na forma in natura. Foram avaliadas a composição centesimal, o pH, a atividade de água, a cor, a capacidade de retenção de água e perda de peso por cozimento da carne e dos hambúrgueres, bem como carboidratos, valor calórico total e análise sensorial dos produtos formulados. A carne ovina apresentou em média 19% de proteína, 5,4% de lipídios, 1,18% de cinzas e 76% de umidade, sendo o conte

    5. Identity of the teacher-researcher in collaborative action research: concerns reflected in a research journal

      OpenAIRE

      Banegas, Darío Luis

      2012-01-01

      <div>In this paper I report the insights of my personal research journal as part of a collaborative action research project I facilitated in a secondary school where I teach English as a foreign language. I kept a journal so as to offer the natural history of my research towards my doctoral degree. In this project I worked together with four participating teachers but I assumed a complex identity as I was a teacher-researcher i.e. doctoral researcher and a teacher. This entailed differe...

    6. Jaume Ferrer de Blanes i Les sentències catòliques del diví poeta Dant. Una mostra de la presència de Dant al renaixement català

      Directory of Open Access Journals (Sweden)

      Josep Llorenç i Blat

      2014-12-01

      Full Text Available Procurador reial i nobiliari, cosmògraf, joier, lapidari, mercader i escriptor, i al capdavall, un ciutadà català honrat, Ferrer (Vidreres, ~1445 – Blanes, 1529 va marxar de ben jove a la cort de Nàpols, al servei del rei Ferran i. Acabada aquesta peripècia italiana va tornar a Blanes al servei del vescomte de Cabrera i de Bas fins que va morir a la mateixa vila al 1529. Un seu criat, disset anys més tard, va editar uns papers esparsos que havia trobat a can Ferrer, les Sentèncias cathòlicas del diví poeta Dant florentí, compilades per lo prudentíssim mossèn Jaume Ferrer de Blanes, que constiueixen un exemple de la presència de Dant al renaixement català. Lord Ferrer (Vidreres,~1445 – Blanes,1529, royal and aristocratic attorney, cosmographer, jewelrer, lapidary, merchant and writer, after all, an honorable Catalan citizen, left early age, at the court of Naples at King Ferdinand’s i service. After this eventful Italian journey he went back to Blanes at the Viscount of Cabrera and Bas’ service, until he died in the same town in 1529. One of his servants, seventeen years later, published some of the documents which were found scattered in Ferrer’s House, Catholic sentences from the divine poet Dante Florentine, compiled by most respectable lord Jaume Ferrer de Blanes, an exemple of the presence of Dante in Catalan Renaissance.

    7. Personality and personal network type

      NARCIS (Netherlands)

      Doeven-Eggens, Lilian; De Fruyt, Filip; Hendriks, A. A. Jolijn; Bosker, Roel J.; Van der Werf, Margaretha P. C.

      2008-01-01

      The association between personality and personal relationships is mostly studied within dyadic relationships. We examined these variables within the context of personal network types. We used Latent Class Analysis to identify groups Of Students with similar role relationships with three focal

    8. Specific components of face perception in the human fusiform gyrus studied by tomographic estimates of magnetoencephalographic signals: a tool for the evaluation of non-verbal communication in psychosomatic paradigms

      Directory of Open Access Journals (Sweden)

      Ioannides Andreas A

      2007-12-01

      Full Text Available Abstract Aims The aim of this study was to determine the specific spatiotemporal activation patterns of face perception in the fusiform gyrus (FG. The FG is a key area in the specialized brain system that makes possible the recognition of face with ease and speed in our daily life. Characterization of FG response provides a quantitative method for evaluating the fundamental functions that contribute to non-verbal communication in various psychosomatic paradigms. Methods The MEG signal was recorded during passive visual stimulus presentation with three stimulus types – Faces, Hands and Shoes. The stimuli were presented separately to the central and peripheral visual fields. We performed statistical parametric mapping (SPM analysis of tomographic estimates of activity to compare activity between a pre- and post-stimulus period in the same object (baseline test, and activity between objects (active test. The time course of regional activation curves was analyzed for each stimulus condition. Results The SPM baseline test revealed a response to each stimulus type, which was very compact at the initial segment of main MFG170. For hands and shoes the area of significant change remains compact. For faces the area expanded widely within a few milliseconds and its boundaries engulfed the other object areas. The active test demonstrated that activity for faces was significantly larger than the activity for hands. The same face specific compact area as in the baseline test was identified, and then again expanded widely. For each stimulus type and presentation in each one of the visual fields locations, the analysis of the time course of FG activity identified three components in the FG: MFG100, MFG170, and MFG200 – all showed preference for faces. Conclusion Early compact face-specific activity in the FG expands widely along the occipito-ventral brain within a few milliseconds. The significant difference between faces and the other object stimuli in MFG

    9. Exposing primary rat retina cell cultures to γ-rays: An in vitro model for evaluating radiation responses.

      Science.gov (United States)

      Gaddini, Lucia; Balduzzi, Maria; Campa, Alessandro; Esposito, Giuseppe; Malchiodi-Albedi, Fiorella; Patrono, Clarice; Matteucci, Andrea

      2018-01-01

      Retinal tissue can receive incidental γ-rays exposure during radiotherapy either of tumors of the eye and optic nerve or of head-and-neck tumors, and during medical diagnostic procedures. Healthy retina is therefore at risk of suffering radiation-related side effects and the knowledge of pathophysiological response of retinal cells to ionizing radiations could be useful to design possible strategies of prevention and management of radiotoxicity. In this study, we have exploited an in vitro model (primary rat retinal cell culture) to study an array of biological effects induced on retinal neurons by γ-rays. Most of the different cell types present in retinal tissue - either of the neuronal or glial lineages - are preserved in primary rat retinal cultures. Similar to the retina in situ, neuronal cells undergo in vitro a maturational development shown by the formation of polarized neuritic trees and operating synapses. Since 2 Gy is the incidental dose received by the healthy retina per fraction when the standard treatment is delivered to the brain, retina cell cultures have been exposed to 1 or 2 Gy of γ-rays at different level of neuronal differentiation in vitro: days in vitro (DIV)2 or DIV8. At DIV9, retinal cultures were analyzed in terms of viability, apoptosis and characterized by immunocytochemistry to identify alterations in neuronal differentiation. After irradiation at DIV2, MTT assay revealed an evident loss of cell viability and βIII-tubulin immunostaining highlighted a marked neuritic damage, indicating that survived neurons showed an impaired differentiation. Differentiated cultures (DIV8) appeared to be more resistant with respect to undifferentiated, DIV2 cultures, both in terms of cell viability and differentiation. Apoptosis evaluated with TUNEL assay showed that irradiation at both DIV2 and DIV8 induced a significant increase in the apoptotic rate. To further investigate the effects of γ-rays on retinal neurons, we evaluated the

    10. The neural architecture of age-related dual-task interferences

      Directory of Open Access Journals (Sweden)

      Witold Xaver Chmielewski

      2014-07-01

      Full Text Available In daily life elderly adults exhibit deficits when dual-tasking is involved. So far these deficits have been verified on a behavioral level in dual-tasking. Yet, the neuronal architecture of these deficits in aging still remains to be explored especially when late-middle aged individuals around 60 years of age are concerned. Neuroimaging studies in young participants concerning dual-tasking were, among others, related to activity in middle frontal (MFG and superior frontal gyrus (SFG and the anterior insula (AI. According to the frontal lobe hypothesis of aging, alterations in these frontal regions (i.e., SFG and MFG might be responsible for cognitive deficits. We measured brain activity using fMRI, while examining age-dependent variations in dual-tasking by utilizing the PRP (psychological refractory period test. Behavioral data showed an increasing PRP effect in late-middle aged adults. The results suggest the age-related deteriorated performance in dual-tasking, especially in conditions of risen complexity. These effects are related to changes in networks involving the anterior insula, the SFG and the MFG. The results suggest that different cognitive subprocesses are affected that mediate the observed dual-tasking problems in late-middle aged individuals.

    11. The neural architecture of age-related dual-task interferences.

      Science.gov (United States)

      Chmielewski, Witold X; Yildiz, Ali; Beste, Christian

      2014-01-01

      In daily life elderly adults exhibit deficits when dual-tasking is involved. So far these deficits have been verified on a behavioral level in dual-tasking. Yet, the neuronal architecture of these deficits in aging still remains to be explored especially when late-middle aged individuals around 60 years of age are concerned. Neuroimaging studies in young participants concerning dual-tasking were, among others, related to activity in middle frontal (MFG) and superior frontal gyrus (SFG) and the anterior insula (AI). According to the frontal lobe hypothesis of aging, alterations in these frontal regions (i.e., SFG and MFG) might be responsible for cognitive deficits. We measured brain activity using fMRI, while examining age-dependent variations in dual-tasking by utilizing the PRP (psychological refractory period) test. Behavioral data showed an increasing PRP effect in late-middle aged adults. The results suggest the age-related deteriorated performance in dual-tasking, especially in conditions of risen complexity. These effects are related to changes in networks involving the AI, the SFG and the MFG. The results suggest that different cognitive subprocesses are affected that mediate the observed dual-tasking problems in late-middle aged individuals.

    12. The neural substrates of procrastination: A voxel-based morphometry study.

      Science.gov (United States)

      Hu, Yue; Liu, Peiwei; Guo, Yiqun; Feng, Tingyong

      2018-03-01

      Procrastination is a pervasive phenomenon across different cultures and brings about lots of serious consequences, including performance, subjective well-being, and even public policy. However, little is known about the neural substrates of procrastination. In order to shed light upon this question, we investigated the neuroanatomical substrates of procrastination across two independent samples using voxel-based morphometry (VBM) method. The whole-brain analysis showed procrastination was positively correlated with the graymatter (GM) volume of clusters in the parahippocampal gyrus (PHG) and the orbital frontal cortex (OFC), while negatively correlated with the GM volume of clusters in the inferior frontal gyrus (IFG) and the middle frontal gyrus (MFG) in sample one (151 participants). We further conducted a verification procedure on another sample (108 participants) using region-of-interest analysis to examine the reliability of these results. Results showed procrastination can be predicted by the GM volume of the OFC and the MFG. The present findings suggest that the MFG and OFC, which are the key regions of self-control and emotion regulation, may play an important role in procrastination. Copyright © 2018 Elsevier Inc. All rights reserved.

    13. Existence of weak solutions to first-order stationary mean-field games with Dirichlet conditions

      KAUST Repository

      Ferreira, Rita

      2018-04-19

      In this paper, we study first-order stationary monotone mean-field games (MFGs) with Dirichlet boundary conditions. While for Hamilton--Jacobi equations Dirichlet conditions may not be satisfied, here, we establish the existence of solutions of MFGs that satisfy those conditions. To construct these solutions, we introduce a monotone regularized problem. Applying Schaefer\\'s fixed-point theorem and using the monotonicity of the MFG, we verify that there exists a unique weak solution to the regularized problem. Finally, we take the limit of the solutions of the regularized problem and using Minty\\'s method, we show the existence of weak solutions to the original MFG.

    14. Dossiê: Trabajo Social y los desafíos ante de la custiòn Social

      Directory of Open Access Journals (Sweden)

      Olga Lucía Vélez Restrepo Lucía Vélez Restrepo

      2012-03-01

      Full Text Available <div>Aunque son muchos los cambios y fracturas que el modelo de desarrollo neoliberal le han acarreado a la Custión Social en este articulo solo me ocuparé de aquellas situaciones generales que le plantean desplazamientos importantes a la profesión, buscando estimular una reflexión crítica sobre los desafíos que se le imponen al Trabajo Social contemporáneo. Los sentidos cambiantes de las prácticas sociales, la pérdida y la ruptura como estructuradoras de las sociedades contemporáneas, las situaciones de violencia política, social y familiar, el desplazamiento forzado, la violación a los derechos elementales, el desempleo y la exclusión, entre otros, le plantean al Travajo Social una serie de desafios en los ámbitos teórico, metodológico, investigativo, académico- formativo y organizacional.div>>
      div>

    15. Using personality neuroscience to study personality disorder.

      Science.gov (United States)

      Abram, Samantha V; DeYoung, Colin G

      2017-01-01

      Personality neuroscience integrates techniques from personality psychology and neuroscience to elucidate the neural basis of individual differences in cognition, emotion, motivation, and behavior. This endeavor is pertinent not only to our understanding of healthy personality variation, but also to the aberrant trait manifestations present in personality disorders and severe psychopathology. In the current review, we focus on the advances and limitations of neuroimaging methods with respect to personality neuroscience. We discuss the value of personality theory as a means to link specific neural mechanisms with various traits (e.g., the neural basis of the "Big Five"). Given the overlap between dimensional models of normal personality and psychopathology, we also describe how researchers can reconceptualize psychopathological disorders along key dimensions, and, in turn, formulate specific neural hypotheses, extended from personality theory. Examples from the borderline personality disorder literature are used to illustrate this approach. We provide recommendations for utilizing neuroimaging methods to capture the neural mechanisms that underlie continuous traits across the spectrum from healthy to maladaptive. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

    16. Addressing the midwifery workforce crisis: evaluating an employment model for undergraduate midwifery students at a tertiary maternity hospital in Melbourne, Australia.

      Science.gov (United States)

      McLachlan, Helen L; Forster, Della A; Ford, Rachael L; Farrell, Tanya

      2011-12-01

      In Victoria, maternity services are under significant strain due to increased numbers of women giving birth and critical workforce shortages. Hospitals have experienced challenges in adequately staffing maternity units, particularly on postnatal wards. In 2008, a tertiary maternity hospital in Melbourne introduced a model where undergraduate midwifery students were employed as Division 2 nurses (SMW_Div2) (enrolled nurses), to work in the postnatal area only. This study explored the pilot employment model from the perspective of the SMW_Div2 and hospital midwives. A web-based survey was administered to hospital midwives and the SMW_Div2s in the employment model in January 2010. The survey explored the views of midwives and SMW_Div2s regarding the perceived impact of the model on workforce readiness, recruitment and retention, and clinical competence and confidence. Forty-seven of 158 midwives (30%) and five of nine SMW_Div2s employed in the model responded to the survey. Both groups considered the model to have benefits for the organisation, including increased: student workforce readiness; clinical confidence and competence; and organisational loyalty. Both groups also considered that the model would facilitate: workforce recruitment; a teaching and learning culture within the organisation; and enhanced partnerships between students, hospitals and universities. Caution was expressed regarding workload and the need for ongoing support for SMW_Div2s working in the model. SMW_Div2s and midwives were positive about the introduction of the paid employment model at the Women's. The findings are consistent with evaluations of similar programs in the nursing setting. The employment model has potential short and long term individual and organisational advantages, which is important in the context of increasing births and workforce shortages. Progression of such models will be contingent on the collaboration and cooperation of the various stakeholders involved in maternity

    17. EFEITO DA SUPLEMENTAÇÃO PROTÉICA SOBRE OS PARÂMETROS CLÍNICOS E PARASITOLÓGICOS DE OVINOS MANTIDOS EM PASTAGEM DE TIFTON 85 EFFECT OF PROTEIN SUPPLEMENTATION ON THE CLINICAL AND PARASITOLOGICAL PARAMETERS OF LAMBS UNDER PASTURE OF TIFTON 85

      Directory of Open Access Journals (Sweden)

      Daniel Maia Nogueira

      2009-12-01

      Full Text Available <div>A suplementação proteica pode ser uma importante ferramenta para os sistemas de produção de ovinos em pastagens tropicais. Objetivou-se com este trabalho avaliar os parâmetros clínicos e parasitológicos de ovinos mantidos em pastagem de Tifton 85 (Cynodon dactylon irrigada, recebendo suplementos com diferentes fontes proteicas. Foram utilizados 28 ovinos castrados e mestiços, distribuídos homogeneamente em quatro tratamentos. Além do controle não suplementado, os tratamentos avaliados foram: farelo de soja, ureia e torta de algodão. Realizou-se a vermifugação dos animais de acordo com o método Famacha©. Não houve diferença significativa (P>0,05 entre os tratamentos para o consumo de matéria seca total, ganho médio diário e ganho de peso total. Foi observado maior consumo de forragem (P<0,05 para os animais mantidos exclusivamente em pastagem. Estes animais também apresentaram maior contagem de ovos por grama de fezes (OPG (P<0,05 em comparação aos suplementados com ureia ou com torta de algodão. Não houve diferença significativa (P>0,05 para os diferentes tons de coloração da conjuntiva nem para o número de animais vermifugados. Observou-se uma prevalência de 72,0% a 83,0% de larvas de Trichostrongylus sp. As diferentes suplementações proteicas não influenciaram as características clínicas nem produtivas dos animais.div>>
      div>>PALAVRAS-CHAVES: Cynodon dactylon, endoparasitas, Famacha©, farelo de soja, torta de algodão, ureia.div> <div>The protein supplementation may be an important tool for sheep production systems in tropical grazing. This work aimed to evaluate parasitological and clinical aspects of lambs under irrigated pasture of Tifton 85 (Cynodon dactylon and receiving supplementation from different protein sources. Twenty-eight, castrated and crossbreed lambs, were used as animal testers and allocated into four treatments. Besides the control with exclusively use of pasture

    18. Balancing personalized medicine and personalized care.

      Science.gov (United States)

      Cornetta, Kenneth; Brown, Candy Gunther

      2013-03-01

      The current description of personalized medicine by the National Institutes of Health is "the science of individualized prevention and therapy." Although physicians are beginning to see the promise of genetic medicine coming to fruition, the rapid pace of sequencing technology, informatics, and computer science predict a revolution in the ability to care for patients in the near future. The enthusiasm expressed by researchers is well founded, but the expectations voiced by the public do not center on advancing technology. Rather, patients are asking for personalized care: a holistic approach that considers physical, mental, and spiritual well-being. This perspective considers psychological, religious, and ethical challenges that may arise as the precision of preventive medicine improves. Psychological studies already highlight the barriers to single gene testing and suggest significant barriers to the predictive testing envisioned by personalized medicine. Certain religious groups will likely mount opposition if they believe personalized medicine encourages embryo selection. If the technology prompts cost-containment discussions, those concerned about the sanctity of life may raise ethical objections. Consequently, the availability of new scientific developments does not guarantee advances in treatment because patients may prove unwilling to receive and act on personalized genetic information. This perspective highlights current efforts to incorporate personalized medicine and personalized care into the medical curriculum, genetic counseling, and other aspects of clinical practice. Because these efforts are generally independent, the authors offer recommendations for physicians and educators so that personalized medicine can be implemented in a manner that meets patient expectations for personalized care.

    19. ENTREVISTA: A Rica Experiência de Formação do e com o MST

      Directory of Open Access Journals (Sweden)

      Maristela Dal Moro*; Geraldo Gasparin**

      2012-02-01

      Full Text Available <div>Na perspectiva de uma maior concretude do projeto ético-político do Serviço Social no Brasil, tem havido nos últimos anos uma forte aproximação entre as unidades de formação profissional e os movimentos sociais, dentre os quais se destaca o Movimento Nacional dos Trabalhadores Sem Terra – MST. Esse importante movimento tem desencadeado uma estratégia de formação de seus militantes e de outros movimentos sociais e, a partir disso, fundou a Escola Nacional Florestan Fernandes. Ali, os militantes tomam contato com um variado cardápio crítico de conteúdos que vão desde a teoria social, o entendimento do modo de produção capitalista, a formação social brasileira e suas particularidades, até discussões sobre o movimento e os processos de formação da consciência. Contudo, essa estratégia vem passando também pelo estreitamento de laços com as universidades públicas, por meio muitas vezes do Serviço Social, criando cursos de graduação para turmas especiais, como na UFRJ, formadas por militantes dos movimentos. Nossa entrevista com Maristela Dal Moro e Geraldo Gasparin interpela dois protagonistas desse processo, na perspectiva de socializar a experiência e, sobretudo, de mostrar como a formação profissional em Serviço Social pode fortalecer os movimentos sociais.div>>
      div>>Por  Alba Tereza Barroso de Castrodiv>

    20. Expression of the GABA(A) receptor alpha6 subunit in cultured cerebellar granule cells is developmentally regulated by activation of GABA(A) receptors

      DEFF Research Database (Denmark)

      Carlson, B X; Belhage, B; Hansen, Gert Helge

      1997-01-01

      Da (alpha6 subunit) radioactive peaks in sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE). In contrast, THIP-treated granule cells at 8 DIV demonstrated a small but significant decrease from control cultures in the photoincorporation of [3H]Ro15-4513 in the 51-kDa peak; however...... that the major effect of THIP was to increase alpha6 subunit clustering on granule cell bodies as well as neurites, 15-fold and sixfold, respectively. Using in situ hybridization, a small THIP-induced increase in alpha6 mRNA was detected at 4 DIV; however, no effect was apparent at 8 DIV. These data suggest...

    1. 78 FR 17251 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing of Proposed Rule...

      Science.gov (United States)

      2013-03-20

      .... First, SEC Rule 15c3-5 requires that, ``financial risk management controls and supervisory procedures... Chapter V, Section 3 Subparagraph (d)(iv) Regarding Obvious Error or Catastrophic Error Review March 15... subparagraph (d)(iv) to provide for how NASDAQ proposes to treat options errors in response to the Regulation...

    2. PERSONALITY TRAITS AND BORDERLINE PERSONALITY DISORDER

      Directory of Open Access Journals (Sweden)

      Senija TAHIROVIC

      2016-12-01

      Full Text Available The people with Borderline Personality Disorder (BPD show pathological personality traits in three of the five domains (APA 2013. In addition to diagnostic criteria for BPD, described by Diagnostic and Statistical Manual of Mental Disorders (DSM-5, the dimensional model of personality disorder, based on five-factor model of personality, seems to gain interest as it promisses to eliminate problems associated with poor-fit, co-morbidity and unclear diagnosis. The purpose of this study is to identify the personality traits by people who are already diagnosed with BPD using the DSM-5 categorical criteria. Based on the theoretical concepts and existing research findings as well as increased interest in the dimensional personality theory, we assume that people diagnosed with BPD will show high levels of pathology on three trait domains: negative affectivity, disinhibition and antagonism. This study was conducted in Germany in psychiatric clinic. Fifteen participants represented a convenience sample, of patients already diagnosed with BPD. For this study Personality Inventory for DSM-5 (PID-5 was used. The findings supported the assumptions that people with BPD show some degree of anxiousness, emotional lability, hostility, impulsivity, risk taking and separation anxiety. The study also found that traits such as distractibility, withdrawal and submissiveness were also present in this participant group. Even though, study was conducted with small number of participants it has provided contribution to the already existing knowledge and understanding in regards to common personality treats for people diagnosed with BPD.

    3. Sex differences in neural responses to stress and alcohol context cues.

      Science.gov (United States)

      Seo, Dongju; Jia, Zhiru; Lacadie, Cheryl M; Tsou, Kristen A; Bergquist, Keri; Sinha, Rajita

      2011-11-01

      Stress and alcohol context cues are each associated with alcohol-related behaviors, yet neural responses underlying these processes remain unclear. This study investigated the neural correlates of stress and alcohol context cue experiences and examined sex differences in these responses. Using functional magnetic resonance imaging, brain responses were examined while 43 right-handed, socially drinking, healthy individuals (23 females) engaged in brief guided imagery of personalized stress, alcohol-cue, and neutral-relaxing scenarios. Stress and alcohol-cue exposure increased activity in the cortico-limbic-striatal circuit (P left anterior insula, striatum, and visuomotor regions (parietal and occipital lobe, and cerebellum). Activity in the left dorsal striatum increased during stress, while bilateral ventral striatum activity was evident during alcohol-cue exposure. Men displayed greater stress-related activations in the mPFC, rostral ACC, posterior insula, amygdala, and hippocampus than women, whereas women showed greater alcohol-cue-related activity in the superior and middle frontal gyrus (SFG/MFG) than men. Stress-induced anxiety was positively associated with activity in emotion-modulation regions, including the medial OFC, ventromedial PFC, left superior-mPFC, and rostral ACC in men, but in women with activation in the SFG/MFG, regions involved in cognitive processing. Alcohol craving was significantly associated with the striatum (encompassing dorsal, and ventral) in men, supporting its involvement in alcohol "urge" in healthy men. These results indicate sex differences in neural processing of stress and alcohol-cue experiences and have implications for sex-specific vulnerabilities to stress- and alcohol-related psychiatric disorders. Copyright © 2010 Wiley-Liss, Inc.

    4. VOGES-PROSKAUER AND COAGULASE TESTS TO THE LABORATORIAL DIAGNOSTIC OF Staphylococcus aureus INCLUDED IN THE EPIDEMIOLOGY OF BOVINE MASTITIS UTILIZAÇÃO DO TESTE DE VOGES-PROSKAUER E DA COAGULASE PARA O DIAGNÓSTICO LABORATORIAL DE Staphylococcus aureus ENVOLVIDOS NA EPIDEMIOLOGIA DA MASTITE BOVINA

      Directory of Open Access Journals (Sweden)

      Luiz Francisco Zafalon

      2009-12-01

      Full Text Available Diagnostic characteristics of acetoin production to the Staphylococcus aureus isolated from milk of mammary quarters of cows with mastitis, orifices of teats and mouthpieces of the liners were studied, in agreement to different coagulation grades presented by strains in the tube coagulase test with rabbit plasma and different rain levels in the environment of the herd. The production of acetoin and the coagulase test were performed after growth on blood agar base supplemented with sheep blood, Gram staining and catalase production. All strains were confirmed by molecular identification at species level by species-specific PCR. Among 329 samples identified, 167 were isolated from milk, 117 from teat orifices and 45 from mouthpieces of the liners. Among these samples, 85.0%, 71.1% and 69.2% strains originated from the milk, mouthpieces and orifices, respectively, presented whole coagulation in the coagulase test. Reduced specificities were obtained to the acetoin production to different coagulation grades on the few rains period as well as on the many rains period. Sensitivities to the acetoin production were higher on the few rains period to all sources and coagulation grades, except to strains from orifices with incomplete coagulation and strains from mouthpieces with complete coagulation. It is recommended the acetoin production test how a good diagnostic strategy to the S. aureus identification, combined with other tests how coagulase, mainly in the milk samples originated from mastitic mammary quarters and on periods with little occurrence of rains.<div>
      div>>KEY WORDS: Animal health, bacteriology, diagnosis, milk.div> <div>Estudaram-se as características diagnósticas do teste de Voges-Proskauer (VP na identificação de Staphylococcus aureus isolados de leite de quartos mamários de vacas com mastite, óstios dos tetos e insufladores dos conjuntos de ordenha, perante diferentes graus de coagulação apresentados pelas cepas

    5. Personality in culture, culture in personality

      OpenAIRE

      I I Kvasova

      2009-01-01

      Personality is a dialectical interconnection between the social and the individual realized via activity, socializing, responsibility towards others, communication. The sense of self-actualization of the personality takes shape in the framework of the given process manifesting itself in various cultural phenomena, especially in art which is to the most extent personalized.

    6. Altered BOLD response during inhibitory and error processing in adolescents with anorexia nervosa.

      Directory of Open Access Journals (Sweden)

      Christina Wierenga

      Full Text Available BACKGROUND: Individuals with anorexia nervosa (AN are often cognitively rigid and behaviorally over-controlled. We previously showed that adult females recovered from AN relative to healthy comparison females had less prefrontal activation during an inhibition task, which suggested a functional brain correlate of altered inhibitory processing in individuals recovered from AN. However, the degree to which these functional brain alterations are related to disease state and whether error processing is altered in AN individuals is unknown. METHODOLOGY/PRINCIPAL FINDINGS: In the current study, ill adolescent AN females (n = 11 and matched healthy comparison adolescents (CA with no history of an eating disorder (n = 12 performed a validated stop signal task (SST during functional magnetic resonance imaging (fMRI to explore differences in error and inhibitory processing. The groups did not differ on sociodemographic variables or on SST performance. During inhibitory processing, a significant group x difficulty (hard, easy interaction was detected in the right dorsal anterior cingulate cortex (ACC, right middle frontal gyrus (MFG, and left posterior cingulate cortex (PCC, which was characterized by less activation in AN compared to CA participants during hard trials. During error processing, a significant group x accuracy (successful inhibit, failed inhibit interaction in bilateral MFG and right PCC was observed, which was characterized by less activation in AN compared to CA participants during error (i.e., failed inhibit trials. CONCLUSION/SIGNIFICANCE: Consistent with our prior findings in recovered AN, ill AN adolescents, relative to CA, showed less inhibition-related activation within the dorsal ACC, MFG and PCC as inhibitory demand increased. In addition, ill AN adolescents, relative to CA, also showed reduced activation to errors in the bilateral MFG and left PCC. These findings suggest that altered prefrontal and cingulate activation during

    7. BULIMIA, ADICCIÓN ALIMENTICIA Y LOS COLORES DE LAS FRUTAS

      Directory of Open Access Journals (Sweden)

      Daniel Jácome Roca

      2009-12-01

      Full Text Available <div id="stcpDiv">

      Resumen

      Los bulímicos son adictos a los alimentos por dos mecanismos posibles: uno, que perciben en forma desmedida las señales subliminales multisensoriales enviadas por los alimentos (el color rojo de la fruta se percibe con más intensidad, por ejemplo. El segundo puede radicar en que los bulímicos sufren de untrastorno en la liberación y/o señalización cerebral de las hormonas de la saciedad alimenticia provenientes del tracto gastrointestinal y del tejido adiposo como la GH-RELINA y la LEPTINA. Este artículo también resume las alteraciones endocrinas en la bulimia, además de las características de los pacientes con trastornos alimenticios como la bulimia nerviosa, la anorexia nerviosa y la enfermedad de las “comilonas compulsivas”.

      Palabras Clave: Trastornos de la alimentación, saciedad, neuropéptidos/apetito, señalizaciones visuales y aromáticas

      Abstract

      Bulimic patients are food-addicts, through two posible mechanisms. One, these persons magnify multisensensorial subliminal signals, sent by foods (i.e., red color of a fruit is perceived with greater intensity. Two, bulimics have a disordered release and/or signaling of brain-gut hormones and adipose-tissue hormones participating in saciety, such as Gh-relin and leptin. This paper includes brief remarks on endocrine dysregulation seen in” bulimia nervosa”. Also, it presents features of eating-disorder patients, such as those suffering from bulimia nervosa, anorexia nervosa y “binge-eating” disorder.

      Key Words: Eating disorders, satiety, neuropeptides/ appetite, visual food cues/odor cues

      div>

    8. Head First Web Design

      CERN Document Server

      Watrall, Ethan

      2008-01-01

      Want to know how to make your pages look beautiful, communicate your message effectively, guide visitors through your website with ease, and get everything approved by the accessibility and usability police at the same time? Head First Web Design is your ticket to mastering all of these complex topics, and understanding what's really going on in the world of web design. Whether you're building a personal blog or a corporate website, there's a lot more to web design than div's and CSS selectors, but what do you really need to know? With this book, you'll learn the secrets of designing effecti

    9. Personality in culture, culture in personality

      Directory of Open Access Journals (Sweden)

      I I Kvasova

      2009-12-01

      Full Text Available Personality is a dialectical interconnection between the social and the individual realized via activity, socializing, responsibility towards others, communication. The sense of self-actualization of the personality takes shape in the framework of the given process manifesting itself in various cultural phenomena, especially in art which is to the most extent personalized.

    10. Personality disorders in persons with gender identity disorder.

      Science.gov (United States)

      Duišin, Dragana; Batinić, Borjanka; Barišić, Jasmina; Djordjevic, Miroslav L; Vujović, Svetlana; Bizic, Marta

      2014-01-01

      Investigations in the field of gender identity disorder (GID) have been mostly related to psychiatric comorbidity and severe psychiatric disorders, but have focused less on personality and personality disorders (PDs). The aim of the study was to assess the presence of PDs in persons with GID as compared to cisgendered (a cisgender person is a person who is content to remain the gender they were assigned at birth) heterosexuals, as well as to biological sex. The study sample consisted of 30 persons with GID and 30 cisgendered heterosexuals from the general population. The assessment of PDs was conducted by application of the self-administered Structured Clinical Interview for DSM-IV Axis II PDs (SCID-II). Persons with GID compared to cisgender heterosexuals have higher presence of PDs, particularly Paranoid PD, avoidant PDs, and comorbid PDs. In addition, MtF (transwomen are people assigned male at birth who identify as women) persons are characterized by a more severe psychopathological profile. Assessment of PDs in persons with GID is of great importance as it comprises a key part of personalized treatment plan tailoring, as well as a prognostic factor for sex-reassignment surgery (SRS) outcome.

    11. The Effects of Rotary Motion on Taste and Odor Ratings: Implications for Space Travel

      Science.gov (United States)

      1987-12-01

      and Romanenko depleted their three month supply of condiments (e.g., horseradish, mustard) in five weeks and had to be resupplied.6 In addition to the...Givaudan Corp., 321 44th St., New York, N.Y., ESROLKO Div. 3 BEEF Imitation Beef Flavor 4452, McCormick & Co., Cockeysville,-Hd-., Industrial Div. 4

    12. Cytoarchitecture in cultured rat neocortex explants

      NARCIS (Netherlands)

      de Jong, B. M.; Ruijter, J. M.; Romijn, H. J.

      1988-01-01

      Neocortex explants obtained from 6-day-old rat pups and cultured in a serum-free medium from 5 hr to 13 days in vitro (DIV) show preservation of cytoarchitectural characteristics. Major changes in the size of the explants and their layers occur during the first 2 DIV. A radial arrangement of neurons

    13. SILAGE OF HIGH MOISTURE GRAIN AND DRY GRAIN OF SORGHUM AS ENERGETIC SOURCE FOR FEMALE CALVES FROM TWO GENETIC GROUPS SILAGEM DE GRÃO ÚMIDO OU GRÃO SECO DE SORGO COMO FONTE ENERGÉTICA PARA BEZERRAS DE DOIS GRUPOS GENÉTICOS

      Directory of Open Access Journals (Sweden)

      João Restle

      2009-12-01

      Full Text Available The performance and development of Charolais (CH and 5/8Nellore 3/8Charolais (5/8NC female calves, feedlot fed with silage of high moisture grain or dry grain of sorghum, were evaluated. The roughage (corn silage:concentrate ratio was 60:40, dry matter (DM basis. Calves average initial weight and age was 96.9±8.5kg and five months. The experimental design was complete randomized, with a 2 x 2 factorial arrangement (types of sorghum grains conservation x genetic groups. No significant interaction was observed between type of sorghum grain conservation and genetic group, for the variables studied. No difference (P>.05 was observed between high moisture and dry grain for daily intake of DM (DMI 3.83 and 3.84 kg DM/day, and digestible energy (DEI 14.59 and 14.92 Mcal/day, respectively. Average daily weight gain (ADW .80 and .83 kg, final weight (FW 165.0 and 166.5 kg, and feed conversion (FC 4.78 and 4.63, were similar for high moisture and dry grain sorghum, respectively. Calves growth parameters according to sorghum grains conservation did not differ (P>.05. The gain of body condition (GBC was higher (P<.05 for the treatment of high moisture grain (.33 points in comparison to dry grain (.22 points. No difference (P>.05 was observed between genetic groups for DMI, DEI, ADW, FC and FW. The 5/8NC compared to the CH calves showed higher (P<.05 final body condition score (3.1 vs 3.0 points, initial (91.12 vs 83.62 cm and final withers height (102.62 vs 94.84 cm and initial (99.37 vs 89.69 cm and final rump height (108.87 vs 101.37 cm. The CH calves had higher (P<.05 thoracic perimeter (24.94 vs 20.56 cm.<div>
      div>>KEY WORDS: Average daily weight gain, crossbreeding, rump height, withers height, thoracic perimeter.div>>
      div> <div>Avaliaram-se o desempenho e o desenvolvimento corporal de bezerras Charolês (CH e 5/8Nelore 3/8Charolês (5/8NC, alimentadas em confinamento com silagem de grão úmido ou seco de sorgo. A rela

    14. Personality Disorders in Persons with Gender Identity Disorder

      Directory of Open Access Journals (Sweden)

      Dragana Duišin

      2014-01-01

      Full Text Available Background. Investigations in the field of gender identity disorder (GID have been mostly related to psychiatric comorbidity and severe psychiatric disorders, but have focused less on personality and personality disorders (PDs. Aims. The aim of the study was to assess the presence of PDs in persons with GID as compared to cisgendered (a cisgender person is a person who is content to remain the gender they were assigned at birth heterosexuals, as well as to biological sex. Methods. The study sample consisted of 30 persons with GID and 30 cisgendered heterosexuals from the general population. The assessment of PDs was conducted by application of the self-administered Structured Clinical Interview for DSM-IV Axis II PDs (SCID-II. Results. Persons with GID compared to cisgender heterosexuals have higher presence of PDs, particularly Paranoid PD, avoidant PDs, and comorbid PDs. In addition, MtF (transwomen are people assigned male at birth who identify as women persons are characterized by a more severe psychopathological profile. Conclusions. Assessment of PDs in persons with GID is of great importance as it comprises a key part of personalized treatment plan tailoring, as well as a prognostic factor for sex-reassignment surgery (SRS outcome.

    15. Microglia change from a reactive to an age-like phenotype with the time in culture

      Science.gov (United States)

      Caldeira, Cláudia; Oliveira, Ana F.; Cunha, Carolina; Vaz, Ana R.; Falcão, Ana S.; Fernandes, Adelaide; Brites, Dora

      2014-01-01

      Age-related neurodegenerative diseases have been associated with chronic neuroinflammation and microglia activation. However, cumulative evidence supports that inflammation only occurs at an early stage once microglia change the endogenous characteristics with aging and switch to irresponsive/senescent and dystrophic phenotypes with disease progression. Thus, it will be important to have the means to assess the role of reactive and aged microglia when studying advanced brain neurodegeneration processes and age-associated related disorders. Yet, most studies are done with microglia from neonates since there are no adequate means to isolate degenerating microglia for experimentation. Indeed, only a few studies report microglia isolation from aged animals, using either short-term cultures or high concentrations of mitogens in the medium, which trigger microglia reactivity. The purpose of this study was to develop an experimental process to naturally age microglia after isolation from neonatal mice and to characterize the cultured cells at 2 days in vitro (DIV), 10 DIV, and 16 DIV. We found that 2 DIV (young) microglia had predominant amoeboid morphology and markers of stressed/reactive phenotype. In contrast, 16 DIV (aged) microglia evidenced ramified morphology and increased matrix metalloproteinase (MMP)-2 activation, as well as reduced MMP-9, glutamate release and nuclear factor kappa-B activation, in parallel with decreased expression of Toll-like receptor (TLR)-2 and TLR-4, capacity to migrate and phagocytose. These findings together with the reduced expression of microRNA (miR)-124, and miR-155, decreased autophagy, enhanced senescence associated beta-galactosidase activity and elevated miR-146a expression, are suggestive that 16 DIV cells mainly correspond to irresponsive/senescent microglia. Data indicate that the model represent an opportunity to understand and control microglial aging, as well as to explore strategies to recover microglia surveillance

    16. Less efficient and costly processes of frontal cortex in childhood chronic fatigue syndrome

      Science.gov (United States)

      Mizuno, Kei; Tanaka, Masaaki; Tanabe, Hiroki C.; Joudoi, Takako; Kawatani, Junko; Shigihara, Yoshihito; Tomoda, Akemi; Miike, Teruhisa; Imai-Matsumura, Kyoko; Sadato, Norihiro; Watanabe, Yasuyoshi

      2015-01-01

      The ability to divide one's attention deteriorates in patients with childhood chronic fatigue syndrome (CCFS). We conducted a study using a dual verbal task to assess allocation of attentional resources to two simultaneous activities (picking out vowels and reading for story comprehension) and functional magnetic resonance imaging. Patients exhibited a much larger area of activation, recruiting additional frontal areas. The right middle frontal gyrus (MFG), which is included in the dorsolateral prefrontal cortex, of CCFS patients was specifically activated in both the single and dual tasks; this activation level was positively correlated with motivation scores for the tasks and accuracy of story comprehension. In addition, in patients, the dorsal anterior cingulate gyrus (dACC) and left MFG were activated only in the dual task, and activation levels of the dACC and left MFG were positively associated with the motivation and fatigue scores, respectively. Patients with CCFS exhibited a wider area of activated frontal regions related to attentional resources in order to increase their poorer task performance with massive mental effort. This is likely to be less efficient and costly in terms of energy requirements. It seems to be related to the pathophysiology of patients with CCFS and to cause a vicious cycle of further increases in fatigue. PMID:26594619

    17. Effects of inhibitory theta burst TMS to different brain sites involved in visuospatial attention - a combined neuronavigated cTBS and behavioural study.

      Science.gov (United States)

      Platz, Thomas; Schüttauf, Johannes; Aschenbach, Julia; Mengdehl, Christine; Lotze, Martin

      2016-01-01

      The study sought to alter visual spatial attention in young healthy subjects by a neuronavigated inhibitory rTMS protocol (cTBS-600) to right brain areas thought to be involved in visual attentional processes, i.e. the temporoparietal junction (TPJ) and the posterior middle frontal gyrus (pMFG), and to test the reversibility of effects by an additional consecutive cTBS to the homologue left brain cortical areas. Healthy subjects showed a leftward bias of the egocentric perspective for both visual-perceptive and visual-exploratory tasks specifically for items presented in the left hemifield. cTBS to the right TPJ, and less systematically to the right pMFG reduced this bias for visuo-spatial and exploratory visuo-motor behaviour. Further, a consecutive cTBS to the left TPJ changed the bias again towards the left for a visual-perceptive task. The evidence supports the notion of an involvement of the right TPJ (and pMFG) in spatial visual attention. The observations further indicate that inhibitory non-invasive brain stimulation (cTBS) to the left TPJ has a potential for reversing a rightward bias of spatial attention when the right TPJ is dysfunctional. Accordingly, the findings could have implications for therapeutic rTMS development for right brain damaged patients with visual neglect.

    18. Less efficient and costly processes of frontal cortex in childhood chronic fatigue syndrome.

      Science.gov (United States)

      Mizuno, Kei; Tanaka, Masaaki; Tanabe, Hiroki C; Joudoi, Takako; Kawatani, Junko; Shigihara, Yoshihito; Tomoda, Akemi; Miike, Teruhisa; Imai-Matsumura, Kyoko; Sadato, Norihiro; Watanabe, Yasuyoshi

      2015-01-01

      The ability to divide one's attention deteriorates in patients with childhood chronic fatigue syndrome (CCFS). We conducted a study using a dual verbal task to assess allocation of attentional resources to two simultaneous activities (picking out vowels and reading for story comprehension) and functional magnetic resonance imaging. Patients exhibited a much larger area of activation, recruiting additional frontal areas. The right middle frontal gyrus (MFG), which is included in the dorsolateral prefrontal cortex, of CCFS patients was specifically activated in both the single and dual tasks; this activation level was positively correlated with motivation scores for the tasks and accuracy of story comprehension. In addition, in patients, the dorsal anterior cingulate gyrus (dACC) and left MFG were activated only in the dual task, and activation levels of the dACC and left MFG were positively associated with the motivation and fatigue scores, respectively. Patients with CCFS exhibited a wider area of activated frontal regions related to attentional resources in order to increase their poorer task performance with massive mental effort. This is likely to be less efficient and costly in terms of energy requirements. It seems to be related to the pathophysiology of patients with CCFS and to cause a vicious cycle of further increases in fatigue.

    19. Less efficient and costly processes of frontal cortex in childhood chronic fatigue syndrome

      Directory of Open Access Journals (Sweden)

      Kei Mizuno

      2015-01-01

      Full Text Available The ability to divide one's attention deteriorates in patients with childhood chronic fatigue syndrome (CCFS. We conducted a study using a dual verbal task to assess allocation of attentional resources to two simultaneous activities (picking out vowels and reading for story comprehension and functional magnetic resonance imaging. Patients exhibited a much larger area of activation, recruiting additional frontal areas. The right middle frontal gyrus (MFG, which is included in the dorsolateral prefrontal cortex, of CCFS patients was specifically activated in both the single and dual tasks; this activation level was positively correlated with motivation scores for the tasks and accuracy of story comprehension. In addition, in patients, the dorsal anterior cingulate gyrus (dACC and left MFG were activated only in the dual task, and activation levels of the dACC and left MFG were positively associated with the motivation and fatigue scores, respectively. Patients with CCFS exhibited a wider area of activated frontal regions related to attentional resources in order to increase their poorer task performance with massive mental effort. This is likely to be less efficient and costly in terms of energy requirements. It seems to be related to the pathophysiology of patients with CCFS and to cause a vicious cycle of further increases in fatigue.

    20. Fusariose em Mudas de Pinus taeda Fusarium disease on Pinus taeda seedlings

      Directory of Open Access Journals (Sweden)

      Albino Grigoletti Júnior

      2011-03-01

      Full Text Available <div>Viveiros comerciais têm apresentado mudas de Pinus taeda com sintomas de murcha e seca de ponteiros e morte, na Região Sul do Brasil. Isolamento em meio BDA e câmara úmida, teste de patogenicidade e microcultivo foram feitos para identificar o patógeno. Uma espécie de Fusarium foi isolada, cuja identificação encontra-se em andamento. Verificou-sepelos postulados de Koch que Fusarium sp. foi o agente causal dessa doença.div>>Nurseries has presented Pinus taeda seedling with symptoms of wilt, tip blight and death, in Southern Region of Brazil. Isolation on PDA medium, moist chamber, pathogenicity test and microculture were made to identify the pathogen. A species of Fusarium was isolated, which is under identification. It was verified by Koch postulates that Fusarium sp. was the causal agent of this disease.div>

    1. Are Moral Disengagement, Neutralization Techniques, and Self-Serving Cognitive Distortions the Same? Developing a Unified Scale of Moral Neutralization of Aggression

      Directory of Open Access Journals (Sweden)

      Denis Ribeaud

      2010-12-01

      Full Text Available <div>Can the three concepts of Neutralization Techniques, Moral Disengagement, and Secondary Self-Serving Cognitive Distortions be conceived theoretically and empiricallydiv>>as capturing the same cognitive processes and thus be measured with one single scale of Moral Neutralization? First, we show how the different approaches overlap conceptually. Second, in Study 1, we verify that four scales derived from the three conceptions of Moral Neutralization are correlated in such a way that they can be conceived as measuring the same phenomenon. Third, building on the results of Study 1, we derive a unified scale of Moral Neutralization which specifically focuses on the neutralization of aggression and test it in a large general population sample of preadolescents (Study 2. Confirmatory factor analyses suggest a good internal consistency and acceptable cross-gender factorial invariance. Correlation analyses with related behavioral and cognitive constructs corroborate the scale’s criterion and convergent validity. In the final section we present a possible integration of Moral Neutralization in a broader framework of crime causation.div>

    2. William Franke, Sulla verità poetica che è superiore alla Storia: Porfirio e la critica filosofica della letteratura William Franke, On the Poetic Truth that is Higher than History: Porphyry and the Philosophical Interpretation of Literature

      Directory of Open Access Journals (Sweden)

      Laura Lucia Rossi

      2010-06-01

      Full Text Available <div>In this article we propose the translation of William Franke’s paper On the Poetic Truth that is Higher than History: Porphyry and the Philosophical Criticism of Literature, in which the American scholar presents the hermeneutic method of the ancient commentators of Homer, with particular reference to the critic practice applied by the Neoplatonic Porphyry in his De Antro Nympharum. With this treatment Franke proposes and hopes for the return to an interpretive method, called philosophical or speculative, also for contemporary criticism.div>>
      div>In questo articolo è presentata la traduzione del saggio di William Franke Sulla verità poetica che è superiore alla Storia: Porfirio e la critica filosofica della letteratura, in cui lo studioso americano presenta il metodo ermeneutico degli antichi commentatori di Omero, con particolare riferimento alla critica praticata dal neoplatonico Porfirio, proponendo e auspicando il ritorno ad una modalità interpretativa, detta filosofica o speculativa, anche per la critica contemporanea.

    3. John Locke on persons and personal identity

      OpenAIRE

      Boeker, Ruth

      2013-01-01

      John Locke claims both that ‘person’ is a forensic term and that personal identity consists in sameness of consciousness. The aim of my dissertation is to explain and critically assess how Locke links his moral and legal account of personhood to his account of personal identity in terms of sameness of consciousness. My interpretation of Locke’s account of persons and personal identity is embedded in Locke’s sortal-dependent account of identity. Locke’s sortal-dependent ac...

    4. 77 FR 43123 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

      Science.gov (United States)

      2012-07-23

      .... Fashion, Inc........ New York, NY May 28, 2011. The following certifications have been issued. The... Division and Mfg. Department, American Achievement Corporation. 81,594 Catalina Marketing St. Petersburg...

    5. 47 CFR 2.1515 - Spectral measurements.

      Science.gov (United States)

      2010-10-01

      ... RULES AND REGULATIONS FCC Procedure for Testing Class A, B and S Emergency Position Indicating... § 2.1515(a) is to be used in this method of measuring signal enhancement. Other methods may be used if.... Amplitude scale: 5 dB/div. Scan width: 20 Hz/div. Center frequency: 121.5 MHz Step (6) Measure and record...

    6. Spatial mapping of mineralization with manganese-enhanced magnetic resonance imaging

      Science.gov (United States)

      Chesnick, I.E.; Centeno, J.A.; Todorov, T.I.; Koenig, A.E.; Potter, K.

      2011-01-01

      Paramagnetic manganese can be employed as a calcium surrogate to sensitize the magnetic resonance imaging (MRI) technique to the processing of calcium during the bone formation process. At low doses, after just 48h of exposure, osteoblasts take up sufficient quantities of manganese to cause marked reductions in the water proton T1 values compared with untreated cells. After just 24h of exposure, 25??M MnCl2 had no significant effect on cell viability. However, for mineralization studies 100??M MnCl2 was used to avoid issues of manganese depletion in calvarial organ cultures and a post-treatment delay of 48h was implemented to ensure that manganese ions taken up by osteoblasts is deposited as mineral. All specimens were identified by their days in vitro (DIV). Using inductively coupled plasma optical emission spectroscopy (ICP-OES), we confirmed that Mn-treated calvariae continued to deposit mineral in culture and that the mineral composition was similar to that of age-matched controls. Notably there was a significant decrease in the manganese content of DIV18 compared with DIV11 specimens, possibly relating to less manganese sequestration as a result of mineral maturation. More importantly, quantitative T1 maps of Mn-treated calvariae showed localized reductions in T1 values over the calvarial surface, indicative of local variations in the surface manganese content. This result was verified with laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS). We also found that ??R1 values, calculated by subtracting the relaxation rate of Mn-treated specimens from the relaxation rate of age-matched controls, were proportional to the surface manganese content and thus mineralizing activity. From this analysis, we established that mineralization of DIV4 and DIV11 specimens occurred in all tissue zones, but was reduced for DIV18 specimens because of mineral maturation with less manganese sequestration. In DIV25 specimens, active mineralization was observed for

    7. Comparing Dimensional Models Assessing Personality Traits and Personality Pathology Among Adult ADHD and Borderline Personality Disorder.

      Science.gov (United States)

      Koerting, Johanna; Pukrop, Ralf; Klein, Philipp; Ritter, Kathrin; Knowles, Mark; Banzhaf, Anke; Gentschow, Laura; Vater, Aline; Heuser, Isabella; Colla, Michael; Roepke, Stefan

      2016-08-01

      This pilot study was a comparison of dimensional models assessing personality traits and personality pathology in a clinical sample of adults diagnosed with ADHD and adults diagnosed with borderline personality disorder (BPD), and a nonclinical control sample of healthy adults. Personality traits were assessed using the NEO-Personality Inventory-Revised (NEO-PI-R) and dimensional personality pathology with the Dimensional Assessment of Personality Pathology-Basic Questionnaire (DAPP-BQ). Adults with ADHD and BPD produced higher Emotional Dysregulation/Neuroticism and Dissocial Behavior scores than controls. For the Extraversion/Inhibitedness scale, adults with BPD produced significantly lower scores than adults with ADHD and controls. On the Conscientiousness/Compulsivity domains, Conscientiousness scores were lower for both disorders, whereas low Compulsivity values were specific to adult ADHD. Our results suggest that patients with adult ADHD and BPD have distinguishable profiles of personality traits and personality pathology. © The Author(s) 2012.

    8. Person-centred healthcare research: a personal influence

      Directory of Open Access Journals (Sweden)

      * Corresponding author: University of Windesheim, Zwolle, The Netherlands Email: am.vandenberg@windesheim.nl Submitted for publication: 3rd November 2017 Accepted for publication: 12th March 2018 Published: 16th May 2018 https://doi.org/10.19043/ipdj.81.011 Abstract Context: This critical reflection is about the positive effects for educational and research settings of participation in a two-day programme entitled ‘Using participatory action research and appreciative inquiry to research healthcare practice’. Aims: To reflect on the journey of positive developments in research and education that started with participation in this programme. Using Caring Conversations (Dewar, 2011 as a reflective framework of questions, this article discusses the journey in order to encourage others to consider the approach of appreciative inquiry to bring to life the concept of co-creation in research and education. Conclusions and implications for practice: Participation in this programme has led to the implementation of a variety of actions in educational and research settings. Central to all these actions is an appreciative approach to co-creation as a counterpart to today’s prevailing problem-based viewpoint. A possible factor behind these developments was the power of vulnerability experienced during the programme, a shared process of transformational learning. Implications for practice: This critical reflection: Provides an invitation to shift from a problem-based focus to a positive revolution Provides an appreciative reflective story about the power of vulnerability as an inspiration for others to move out of their comfort zone and seek to discover their own exceptionality Supports a shift from a facilitator-led to a co-creation approach in doing research and teaching with older adults Keywords: Emotional touchpoints, appreciative inquiry, Caring Conversations, practice development, co-creation, transformational learning theory   IDEAS AND INFLUENCES Person-centred healthcare research: a personal influence Hazel M. Chapman

      2018-05-01

      Full Text Available This commentary assesses the contribution made by the person-centred healthcare research of McCormack et al (2017 to research methodology and our ability to evaluate an organisation’s claims to be person-centred. It discusses the importance of person-centred ethical approaches within rigorous research methodologies.

    9. Self-organized criticality in developing neuronal networks.

      Directory of Open Access Journals (Sweden)

      Christian Tetzlaff

      Full Text Available Recently evidence has accumulated that many neural networks exhibit self-organized criticality. In this state, activity is similar across temporal scales and this is beneficial with respect to information flow. If subcritical, activity can die out, if supercritical epileptiform patterns may occur. Little is known about how developing networks will reach and stabilize criticality. Here we monitor the development between 13 and 95 days in vitro (DIV of cortical cell cultures (n = 20 and find four different phases, related to their morphological maturation: An initial low-activity state (≈19 DIV is followed by a supercritical (≈20 DIV and then a subcritical one (≈36 DIV until the network finally reaches stable criticality (≈58 DIV. Using network modeling and mathematical analysis we describe the dynamics of the emergent connectivity in such developing systems. Based on physiological observations, the synaptic development in the model is determined by the drive of the neurons to adjust their connectivity for reaching on average firing rate homeostasis. We predict a specific time course for the maturation of inhibition, with strong onset and delayed pruning, and that total synaptic connectivity should be strongly linked to the relative levels of excitation and inhibition. These results demonstrate that the interplay between activity and connectivity guides developing networks into criticality suggesting that this may be a generic and stable state of many networks in vivo and in vitro.

    10. Cultural influences on the neural correlate of moral decision making processes.

      Science.gov (United States)

      Han, Hyemin; Glover, Gary H; Jeong, Changwoo

      2014-02-01

      This study compares the neural substrate of moral decision making processes between Korean and American participants. By comparison with Americans, Korean participants showed increased activity in the right putamen associated with socio-intuitive processes and right superior frontal gyrus associated with cognitive control processes under a moral-personal condition, and in the right postcentral sulcus associated with mental calculation in familiar contexts under a moral-impersonal condition. On the other hand, American participants showed a significantly higher degree of activity in the bilateral anterior cingulate cortex (ACC) associated with conflict resolution under the moral-personal condition, and in the right medial frontal gyrus (MFG) associated with simple cognitive branching in non-familiar contexts under the moral-impersonal condition when a more lenient threshold was applied, than Korean participants. These findings support the ideas of the interactions between the cultural background, education, and brain development, proposed in the field of cultural psychology and educational psychology. The study introduces educational implications relevant to moral psychologists and educators. Copyright © 2013 Elsevier B.V. All rights reserved.

    11. Personality disorders and normal personality dimensions in obsessive-compulsive disorder.

      Science.gov (United States)

      Samuels, J; Nestadt, G; Bienvenu, O J; Costa, P T; Riddle, M A; Liang, K Y; Hoehn-Saric, R; Grados, M A; Cullen, B A

      2000-11-01

      Little is known about personality disorders and normal personality dimensions in relatives of patients with obsessive-compulsive disorder (OCD). To determine whether specific personality characteristics are part of a familial spectrum of OCD. Clinicians evaluated personality disorders in 72 OCD case and 72 control probands and 198 case and 207 control first-degree relatives. The selfcompleted Revised NEO Personality Inventory was used for assessment of normal personality dimensions. The prevalence of personality disorders and scores on normal personality dimensions were compared between case and control probands and between case and control relatives. Case probands and case relatives had a high prevalence of obsessive-compulsive personality disorder (OCPD) and high neuroticism scores. Neuroticism was associated with OCPD in case but not control relatives. Neuroticism and OCPD may share a common familial aetiology with OCD.

    12. Personality and Development in Childhood: A Person-Centered Approach.

      Science.gov (United States)

      Hart, Daniel; Atkins, Robert; Fegley, Suzanne

      2003-01-01

      Applied a person-centered approach to childhood personality development in 28 diverse samples of 3- to 6-year-olds studied over 6 years. Identified resilient, overcontrolled, and undercontrolled personality types. Found that the undercontrolled personality type related to intellectual decline over 6 years. The number of family risks predicted…

    13. Personal Branding

      OpenAIRE

      Climent i Martí, Jordi

      2017-01-01

      Proyecto Fin de Grado leído en la Universidad Rey Juan Carlos en el curso académico 2013/2014. Director: Cristina Ayala del Pino Con este Trabajo Fin de Grado he querido aproximar el concepto del Personal Branding y de marca personal como la herramienta para diferenciarse en el entorno profesional. Partiendo con la definición del concepto, su construcción, el panorama actual, compaginar empleo con marca personal y acabando con la visión personal de un gurú de la Marca Person...

    14. Personality Development

      Directory of Open Access Journals (Sweden)

      Osman Ozdemir

      2012-12-01

      Full Text Available Personality is the integration of characteristics acquired or brought by birth which separate the individual from others. Personality involves aspects of the individual's mental, emotional, social, and physical features in continuum. Several theories were suggested to explain developmental processes of personality. Each theory concentrates on one feature of human development as the focal point, then integrates with other areas of development in general. Most theories assume that childhood, especially up to 5-6 years, has essential influence on development of personality. The interaction between genetic and environmental factors reveals a unique personality along growth and developmental process. It could be said that individual who does not have any conflict between his/her basic needs and society's, has well-developed and psychologically healthy personality.

    15. Mesa en cuello por Mycobacterium tuberculosis en un paciente infectado por HIV A case of cervical mass due to mycobacterium tuberculosis in an HIV infected patient

      Directory of Open Access Journals (Sweden)

      Mónica Soto

      1995-02-01

      Full Text Available Se presenta el caso de un paciente de sexo masculino con diagnóstico de infección por HIV quien presentó una masa en cuello de 7 x 10 cm, dolorosa, de consistencia dura, adherida, no pulsátil, con edema de la piel adyacente y sin otros signos asociados. La evolución fue de 6 meses. Los estudios de la masa y el esputo dieron como resultado el aislamiento de M. tuberculosis, lo que permitió un adecuado enfoque terapéutico y por consiguiente una respuesta clínica satisfactoria <div>We report on the case of an HIV-infected male with Mycobacterium tuberculosis infection, manifested as both pulmonary involvement and a cervical mass; lung infection was proven by culture; pathological study of the mass revealed both chronic granulomatous infection and acidfast bacilli. Response to treatment was favorablediv>>and rapid. We suggest that every fluid and tissue obtained from HIV-positive patients be routinely stained and cultured for mycobacteria.div>

    16. Personality traits in persons with manganese poisoning

      Energy Technology Data Exchange (ETDEWEB)

      Platonov, A A

      1976-10-01

      Results of studies with the Minnesota Multiphasic Personality Inventory (MMPI) in 3 groups of arc welders with various degrees of manganese poisoning (22 symptom-free, 23 with functional disturbances, 55 with organic symptoms) and 50 controls were discussed. There was a close relation between the severity of the poisoning and quantitative and qualitative personality changes. Personality tests are considered a useful addition to the clinical diagnosis of chronic manganese poisoning.

    17. 77 FR 64356 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

      Science.gov (United States)

      2012-10-19

      ... Torrance, CA September 18, 2011. 81,984 Leviton Manufacturing El Paso, TX September 19, 2011. Company, Inc... Motors Vehicle Mfg. I hereby certify that the aforementioned determinations were issued during the period...

    18. DSM-5 Personality Traits and DSM-IV Personality Disorders

      Science.gov (United States)

      Hopwood, Christopher J.; Thomas, Katherine M.; Markon, Kristian E.; Wright, Aidan G.C.; Krueger, Robert F.

      2014-01-01

      Two issues pertinent to the DSM-5 proposal for personality pathology, the recovery of DSM-IV personality disorders (PDs) by proposed DSM-5 traits and the validity of the proposed DSM-5 hybrid model which incorporates both personality pathology symptoms and maladaptive traits, were evaluated in a large undergraduate sample (N = 808). Proposed DSM-5 traits as assessed with the Personality Inventory for DSM-5 explained a substantial proportion of variance in DSM-IV PDs as assessed with the Personality Diagnostic Questionnaire-4+, and trait indicators of the six proposed DSM-5 PDs were mostly specific to those disorders with some exceptions. Regression analyses support the DSM-5 hybrid model in that pathological traits and an indicator of general personality pathology severity provided incremental information about PDs. Findings are discussed in the context of broader issues around the proposed DSM-5 model of personality disorders. PMID:22250660

    19. Hostile Attribution Bias Mediates the Relationship Between Structural Variations in the Left Middle Frontal Gyrus and Trait Angry Rumination

      Directory of Open Access Journals (Sweden)

      Yueyue Wang

      2018-04-01

      Full Text Available Angry rumination is a common mental phenomenon which may lead to negative social behaviors such as aggression. Although numerous neuroimaging studies have focused on brain area activation during angry rumination, to our knowledge no study has examined the neuroanatomical and cognitive mechanisms of this process. In this study, we conducted a voxel-based morphometry analysis, using a region of interest analysis to identify the structural and cognitive mechanisms underlying individual differences in trait angry rumination (as measured by the Angry Rumination Scale in a sample of 82 undergraduate students. We found that angry rumination was positively correlated with gray matter density in the left middle frontal gyrus (left-MFG, which is implicated in inhibition control, working memory, and emotional regulation. The mediation analysis further revealed that hostile attribution bias (as measured by the Social Information Processing–Attribution Bias Questionnaire acted as a cognitive mechanism underlying the positive association between the left-MFG gray matter density and trait angry rumination. These findings suggest that hostile attribution bias may contribute to trait angry rumination, while the left-MFG may play an important role in the development of hostile attribution bias and trait angry rumination. The study reveals the brain mechanisms of trait angry rumination and plays a role in revealing the cognitive mechanisms of the development of trait angry rumination.

    20. Different Roles of COMT and HTR2A Genotypes in Working Memory Subprocesses.

      Directory of Open Access Journals (Sweden)

      Hirohito M Kondo

      Full Text Available Working memory is linked to the functions of the frontal areas, in which neural activity is mediated by dopaminergic and serotonergic tones. However, there is no consensus regarding how the dopaminergic and serotonergic systems influence working memory subprocesses. The present study used an imaging genetics approach to examine the interaction between neurochemical functions and working memory performance. We focused on functional polymorphisms of the catechol-O-methyltransferase (COMT Val(158Met and serotonin 2A receptor (HTR2A -1438G/A genes, and devised a delayed recognition task to isolate the encoding, retention, and retrieval processes for visual information. The COMT genotypes affected recognition accuracy, whereas the HTR2A genotypes were associated with recognition response times. Activations specifically related to working memory were found in the right frontal and parietal areas, such as the middle frontal gyrus (MFG, inferior frontal gyrus (IFG, anterior cingulate cortex (ACC, and inferior parietal lobule (IPL. MFG and ACC/IPL activations were sensitive to differences between the COMT genotypes and between the HTR2A genotypes, respectively. Structural equation modeling demonstrated that stronger connectivity in the ACC-MFG and ACC-IFG networks is related to better task performance. The behavioral and fMRI results suggest that the dopaminergic and serotonergic systems play different roles in the working memory subprocesses and modulate closer cooperation between lateral and medial frontal activations.

    1. Assessment of flood-induced changes of phytoplankton along a river-floodplain system using the morpho-functional approach.

      Science.gov (United States)

      Mihaljević, Melita; Spoljarić, Dubravka; Stević, Filip; Zuna Pfeiffer, Tanja

      2013-10-01

      In this research, we aimed to find out how the differences in hydrological connectivity between the main river channel and adjacent floodplain influence the changes in phytoplankton community structure along a river-floodplain system. The research was performed in the River Danube floodplain (Croatian river section) in the period 2008-2009 characterised by different flooding pattern on an annual time scale. By utilising the morpho-functional approach and multivariate analyses, the flood-derived structural changes of phytoplankton were analysed. The lake stability during the isolation phase triggered the specific pattern of morpho-functional groups (MFG) which were characterised by cyanobacterial species achieving very high biomass. Adversely, the high water turbulence in the lake during the frequent and extreme flooding led to evident similarity between lake and river assemblages. Besides different diatom species (groups of small and large centrics and pennates), which are the most abundant representatives in the river phytoplankton, many other groups such as cryptophytes and colonial phytomonads appeared to indicate altered conditions in the floodplain driven by flooding. Having different functional properties, small centric diatom taxa sorted to only one MFG cannot clearly reflect environmental changes that are shown by the species-level pattern. Disadvantages in using the MFG approach highlight that it is still necessary to combine it with taxonomical approach in monitoring of phytoplankton in the river-floodplain ecosystems.

    2. Intra-Personal and Inter-Personal Kinetic Synergies During Jumping

      Directory of Open Access Journals (Sweden)

      Slomka Kajetan

      2015-12-01

      Full Text Available We explored synergies between two legs and two subjects during preparation for a long jump into a target. Synergies were expected during one-person jumping. No such synergies were expected between two persons jumping in parallel without additional contact, while synergies were expected to emerge with haptic contact and become stronger with strong mechanical contact. Subjects performed jumps either alone (each foot standing on a separate force platform or in dyads (parallel to each other, each person standing on a separate force platform without any contact, with haptic contact, and with strong coupling. Strong negative correlations between pairs of force variables (strong synergies were seen in the vertical force in one-person jumps and weaker synergies in two-person jumps with the strong contact. For other force variables, only weak synergies were present in one-person jumps and no negative correlations between pairs of force variable for two-person jumps. Pairs of moment variables from the two force platforms at steady state showed positive correlations, which were strong in one-person jumps and weaker, but still significant, in two-person jumps with the haptic and strong contact. Anticipatory synergy adjustments prior to action initiation were observed in oneperson trials only. We interpret the different results for the force and moment variables at steady state as reflections of postural sway.

    3. Investigation into the formation of the scrape-off layer density shoulder in JET ITER-like wall L-mode and H-mode plasmas

      Science.gov (United States)

      Wynn, A.; Lipschultz, B.; Cziegler, I.; Harrison, J.; Jaervinen, A.; Matthews, G. F.; Schmitz, J.; Tal, B.; Brix, M.; Guillemaut, C.; Frigione, D.; Huber, A.; Joffrin, E.; Kruzei, U.; Militello, F.; Nielsen, A.; Walkden, N. R.; Wiesen, S.; Contributors, JET

      2018-05-01

      The low temperature boundary layer plasma (scrape-off layer or SOL) between the hot core and the surrounding vessel determines the level of power loading, erosion and implantation of material surfaces, and thus the viability of tokamak-based fusion as an energy source. This study explores mechanisms affecting the formation of flattened density profiles, so-called ‘density shoulders’, in the low-field side (LFS) SOL, which modify ion and neutral fluxes to surfaces—and subsequent erosion. We find that increases in SOL parallel resistivity, Λdiv (=[L || ν eiΩi]/c sΩe), postulated to lead to shoulder growth through changes in SOL turbulence characteristics, correlates with increases in SOL shoulder amplitude, A s, only under a subset of conditions (D2-fuelled L-mode density scans with outer strike point on the horizontal target). Λdiv fails to correlate with A s for cases of N2 seeding or during sweeping of the strike point across the horizontal target. The limited correlation of Λdiv and A s is also found for H-mode discharges. Thus, while it may be necessary for Λdiv to be above a threshold of ~1 for shoulder formation and/or growth, another mechanism is required. More significantly, we find that in contrast to parallel resistivity, outer divertor recycling, as quantified by the total outer divertor Balmer D α emission, I-D α , does scale with A s where Λdiv does and even where Λdiv does not. Divertor recycling could lead to SOL density shoulder formation through: (a) reducing the parallel to the field flow (loss) of ions out of the SOL to the divertor; and (b) changes in radial electric fields which lead to E  ×  B poloidal flows as well as potentially affecting SOL turbulence birth characteristics. Thus, changes in divertor recycling may be the sole process involved in bringing about SOL density shoulders or it may be that it acts in tandem with parallel resistivity.

    4. Changes of muscarinic cholinergic receptors during aging process of primary cultured neutrons

      International Nuclear Information System (INIS)

      Fan Guohuang; Yi Ningyu; Xia Zongqin

      1996-01-01

      The dynamic changes of muscarinic receptor density and its reactivity during aging process in primary cultured neutrons were studied. Muscarinic receptor density was measured by 3 H-QNB binding assay, and muscarinic receptor reactivity was assessed by carbachol stimulation of cGMP formation, the latter was measured by RIA. After 2 weeks' incubation of neonatal rat brain cells, the nutrients began to rupture and the cell bodies shrank markedly showing senescent feature. The muscarinic receptor density reached peak at the 12th day in vitro (12 DIV), but the muscarinic receptor reactivity reached peak at 9 DIV and declined significantly at 12 DIV. The results demonstrated that during aging process of primary cultured neutrons, the decline of muscarinic receptor reactivity is likely prior to the decrease of receptor density

    5. Neural correlates of reward processing in healthy siblings of patients with schizophrenia

      Directory of Open Access Journals (Sweden)

      Esther eHanssen

      2015-09-01

      Full Text Available Deficits in motivational behavior and psychotic symptoms often observed in schizophrenia (SZ may be driven by dysfunctional reward processing (RP. RP can be divided in two different stages; reward anticipation and reward consumption. Aberrant processing during reward anticipation seems to be related to SZ. Studies in patients with SZ have found less activation in the ventral striatum (VS during anticipation of reward, but these findings do not provide information on effect of the genetic load on reward processing. Therefore, this study investigated RP in healthy first-degree relatives of SZ patients. The sample consisted of 94 healthy siblings of SZ patients and 57 healthy controls. Participants completed a classic RP task, the Monetary Incentive Delay task, during functional magnetic resonance imaging (fMRI. As expected, there were no behavioral differences between groups. In contrast to our expectations, we found no differences in any of the anticipatory reward related brain areas (region of interest analyses. Whole-brain analyses did reveal group differences during both reward anticipation and reward consumption; during reward anticipation siblings showed less deactivation in the insula, posterior cingulate cortex (PCC and medial frontal gyrus (MFG than controls. During reward consumption siblings showed less deactivation in the PCC and the right MFG compared to controls and activation in contrast to deactivation in controls in the precuneus and the left MFG. Exclusively in siblings, MFG activity correlated positively with subclinical negative symptoms. These regions are typically associated with the default mode network (DMN, which normally shows decreases in activation during task-related cognitive processes. Thus, in contrast to prior literature in patients with SZ, the results do not point to altered brain activity in classical RP brain areas, such as the VS. However, the weaker deactivation found outside the reward-related network in

    6. Core features of personality disorder: differentiating general personality dysfunctioning from personality traits

      NARCIS (Netherlands)

      Berghuis, H.; Kamphuis, J.H.; Verheul, R.

      2012-01-01

      The distinction between general personality dysfunctioning (GPD) and specific personality traits (SPT) is an important focus of attention in the proposed revisions of the DSM-5. The present study explores the distinction between GPD and SPT using the self-report questionnaires General Assessment of

    7. Explicit Solutions for One-Dimensional Mean-Field Games

      KAUST Repository

      Prazeres, Mariana

      2017-04-05

      In this thesis, we consider stationary one-dimensional mean-field games (MFGs) with or without congestion. Our aim is to understand the qualitative features of these games through the analysis of explicit solutions. We are particularly interested in MFGs with a nonmonotonic behavior, which corresponds to situations where agents tend to aggregate. First, we derive the MFG equations from control theory. Then, we compute explicit solutions using the current formulation and examine their behavior. Finally, we represent the solutions and analyze the results. This thesis main contributions are the following: First, we develop the current method to solve MFG explicitly. Second, we analyze in detail non-monotonic MFGs and discover new phenomena: non-uniqueness, discontinuous solutions, empty regions and unhappiness traps. Finally, we address several regularization procedures and examine the stability of MFGs.

    8. Age-related reduction of adaptive brain response during semantic integration is associated with gray matter reduction.

      Directory of Open Access Journals (Sweden)

      Zude Zhu

      Full Text Available While aging is associated with increased knowledge, it is also associated with decreased semantic integration. To investigate brain activation changes during semantic integration, a sample of forty-eight 25-75 year-old adults read sentences with high cloze (HC and low cloze (LC probability while functional magnetic resonance imaging was conducted. Significant age-related reduction of cloze effect (LC vs. HC was found in several regions, especially the left middle frontal gyrus (MFG and right inferior frontal gyrus (IFG, which play an important role in semantic integration. Moreover, when accounting for global gray matter volume reduction, the age-cloze correlation in the left MFG and right IFG was absent. The results suggest that brain structural atrophy may disrupt brain response in aging brains, which then show less brain engagement in semantic integration.

    9. Sex, Lies and fMRI—Gender Differences in Neural Basis of Deception

      Science.gov (United States)

      Falkiewicz, Marcel; Szeszkowski, Wojciech; Grabowska, Anna; Szatkowska, Iwona

      2012-01-01

      Deception has always been a part of human communication as it helps to promote self-presentation. Although both men and women are equally prone to try to manage their appearance, their strategies, motivation and eagerness may be different. Here, we asked if lying could be influenced by gender on both the behavioral and neural levels. To test whether the hypothesized gender differences in brain activity related to deceptive responses were caused by differential socialization in men and women, we administered the Gender Identity Inventory probing the participants’ subjective social sex role. In an fMRI session, participants were instructed either to lie or to tell the truth while answering a questionnaire focusing on general and personal information. Only for personal information, we found differences in neural responses during instructed deception in men and women. The women vs. men direct contrast revealed no significant differences in areas of activation, but men showed higher BOLD signal compared to women in the left middle frontal gyrus (MFG). Moreover, this effect remained unchanged when self-reported psychological gender was controlled for. Thus, our study showed that gender differences in the neural processes engaged during falsifying personal information might be independent from socialization. PMID:22952631

    10. Sex, lies and fMRI--gender differences in neural basis of deception.

      Directory of Open Access Journals (Sweden)

      Artur Marchewka

      Full Text Available Deception has always been a part of human communication as it helps to promote self-presentation. Although both men and women are equally prone to try to manage their appearance, their strategies, motivation and eagerness may be different. Here, we asked if lying could be influenced by gender on both the behavioral and neural levels. To test whether the hypothesized gender differences in brain activity related to deceptive responses were caused by differential socialization in men and women, we administered the Gender Identity Inventory probing the participants' subjective social sex role. In an fMRI session, participants were instructed either to lie or to tell the truth while answering a questionnaire focusing on general and personal information. Only for personal information, we found differences in neural responses during instructed deception in men and women. The women vs. men direct contrast revealed no significant differences in areas of activation, but men showed higher BOLD signal compared to women in the left middle frontal gyrus (MFG. Moreover, this effect remained unchanged when self-reported psychological gender was controlled for. Thus, our study showed that gender differences in the neural processes engaged during falsifying personal information might be independent from socialization.

    11. Syntax of Emotional Narratives of Persons Diagnosed with Antisocial Personality

      Science.gov (United States)

      Gawda, Barbara

      2010-01-01

      The aim of this study was to show some specificity of syntax of narratives created by persons diagnosed with antisocial personality. The author attempted to verify and supplement information that persons with antisocial personality have an incapacity for emotional language. Scores of 60 prisoners with high antisocial tendencies, 40 prisoners with…

    12. Linking person perception and person knowledge in the human brain.

      Science.gov (United States)

      Greven, Inez M; Downing, Paul E; Ramsey, Richard

      2016-04-01

      Neuroscience research has examined separately how we detect human agents on the basis of their face and body (person perception) and how we reason about their thoughts, traits or intentions (person knowledge). Neuroanatomically distinct networks have been associated with person perception and person knowledge, but it remains unknown how multiple features of a person (e.g. thin and kind) are linked to form a holistic identity representation. In this fMRI experiment, we investigated the hypothesis that when encountering another person specialised person perception circuits would be functionally coupled with circuits involved in person knowledge. In a factorial design, we paired bodies or names with trait-based or neutral statements, and independent localiser scans identified body-selective and mentalising networks. When observing a body paired with a trait-implying statement, functional connectivity analyses demonstrated that body-selective patches in bilateral fusiform gyri were functionally coupled with nodes of the mentalising network. We demonstrate that when forming a representation of a person circuits for representing another person's physical appearance are linked to circuits that are engaged when reasoning about trait-based character. These data support the view that a 'who' system for social cognition involves communication between perceptual and inferential mechanisms when forming a representation of another's identity. © The Author (2016). Published by Oxford University Press.

    13. The Social Cognitive Theory of Personality in the Context of Personal Marketing

      Directory of Open Access Journals (Sweden)

      Zvjezdana Penava Brekalo

      2010-07-01

      Full Text Available The starting point of personal marketing is an individual, i.e. a person. Personal marketing, in the sense of the narrowest level of marketing, has a markedly interdisciplinary character, because it relies on the knowledge of psychology - the science of psychological characteristics of a person. Psychological factors of personal marketing, like personality, behaviour, emotions, temperament, character and intelligence are numerous, but in this paper some of the psychological categories relevant for the implementation of personal marketing are singled out and described. These are primarily the self, personal image, needs, desires, motives, motivation, attitudes and behaviour seen from the viewpoint of social cognitive theory of personality in the context of personal marketing.

    14. [Relation between personality traits and personal values in cocaine-dependent patients].

      Science.gov (United States)

      Saiz, Jesús; Álvaro, José Luis; Martínez, Isabel

      2011-01-01

      To describe the relationship between personal values and personality traits in cocaine-using patients and analyze their specificity in the explanation of different types of constructs. A study was carried out to explore the association between these variables in a group of 230 patients receiving treatment for cocaine dependence. The Portrait Values Questionnaire was used for measuring personal values, while the Big-Five Factors Questionnaire was used to measure personality traits. In addition, we explored the relationship of values and traits with the variables "degree of satisfaction with life" (life satisfaction) and "belonging to a religious association" (religiosity). A significant association was found between personal values and personality traits. At the same time, their conceptual and empirical differences were revealed, as it was demonstrated that personal values better explain "belonging to a religious association", whilst personality traits better explain "degree of satisfaction with life". Thus, it was found that personal values better explain behaviours that depend on greater cognitive control, while personality traits would have more influence on tendencies and behaviours that are subject to lower cognitive control levels. Considering the relationship between the two constructs, and given that cocaine use is associated with both high and low cognitive control, in explanations of cocaine use it would be appropriate to take into account the explanatory contribution of personal values and personality traits in a complementary way.

    15. Discovering Your Personality: A Group Exercise in Personal Sensemaking

      Science.gov (United States)

      Anderson, Marc H.

      2008-01-01

      Personality affects a wide variety of issues in organizational behavior, human resource management, and strategic management. Instructors teaching personality often have students take personality tests and then give them their scores. This passive approach to giving test feedback suffers from several weaknesses dealing with distinct perceptual…

    16. PERSON-Personalized Expert Recommendation System for Optimized Nutrition.

      Science.gov (United States)

      Chen, Chih-Han; Karvela, Maria; Sohbati, Mohammadreza; Shinawatra, Thaksin; Toumazou, Christofer

      2018-02-01

      The rise of personalized diets is due to the emergence of nutrigenetics and genetic tests services. However, the recommendation system is far from mature to provide personalized food suggestion to consumers for daily usage. The main barrier of connecting genetic information to personalized diets is the complexity of data and the scalability of the applied systems. Aiming to cross such barriers and provide direct applications, a personalized expert recommendation system for optimized nutrition is introduced in this paper, which performs direct to consumer personalized grocery product filtering and recommendation. Deep learning neural network model is applied to achieve automatic product categorization. The ability of scaling with unknown new data is achieved through the generalized representation of word embedding. Furthermore, the categorized products are filtered with a model based on individual genetic data with associated phenotypic information and a case study with databases from three different sources is carried out to confirm the system.

    17. Personality traits and personal values: a meta-analysis.

      Science.gov (United States)

      Parks-Leduc, Laura; Feldman, Gilad; Bardi, Anat

      2015-02-01

      Personality traits and personal values are important psychological characteristics, serving as important predictors of many outcomes. Yet, they are frequently studied separately, leaving the field with a limited understanding of their relationships. We review existing perspectives regarding the nature of the relationships between traits and values and provide a conceptual underpinning for understanding the strength of these relationships. Using 60 studies, we present a meta-analysis of the relationships between the Five-Factor Model (FFM) of personality traits and the Schwartz values, and demonstrate consistent and theoretically meaningful relationships. However, these relationships were not generally large, demonstrating that traits and values are distinct constructs. We find support for our premise that more cognitively based traits are more strongly related to values and more emotionally based traits are less strongly related to values. Findings also suggest that controlling for personal scale-use tendencies in values is advisable. © 2014 by the Society for Personality and Social Psychology, Inc.

    18. 29 CFR 778.406 - Nonovertime hours as well as overtime hours must be irregular if section 7(f) is to apply.

      Science.gov (United States)

      2010-07-01

      ... DIRECTLY RELATED TO REGULATIONS OVERTIME COMPENSATION Exceptions From the Regular Rate Principles.... Midland Finance Co. (N.D. Ga.), 16 WH Cases 141; Trager v. J. E. Plastics Mfg. Co. (S.D.N.Y.), 13 WH Cases...

    19. 31 CFR 594.315 - United States person; U.S. person.

      Science.gov (United States)

      2010-07-01

      ... (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY GLOBAL TERRORISM SANCTIONS REGULATIONS General Definitions § 594.315 United States person; U.S. person. The term United States person or...

    20. Why the Personal Competencies Matter. Connect: Making Learning Personal

      Science.gov (United States)

      Redding, Sam

      2015-01-01

      This issue in the "Connect" series is a field report that discusses how a student's personal competencies--cognitive, metacognitive, motivational, and social/emotional--propel learning and other forms of goal attainment. These personal competencies are personal to the individual in their shape, size, and effect, but they are enhanced by…

    1. Quantification of HTLV-1 Clonality and TCR Diversity

      Science.gov (United States)

      Laydon, Daniel J.; Melamed, Anat; Sim, Aaron; Gillet, Nicolas A.; Sim, Kathleen; Darko, Sam; Kroll, J. Simon; Douek, Daniel C.; Price, David A.; Bangham, Charles R. M.; Asquith, Becca

      2014-01-01

      Estimation of immunological and microbiological diversity is vital to our understanding of infection and the immune response. For instance, what is the diversity of the T cell repertoire? These questions are partially addressed by high-throughput sequencing techniques that enable identification of immunological and microbiological “species” in a sample. Estimators of the number of unseen species are needed to estimate population diversity from sample diversity. Here we test five widely used non-parametric estimators, and develop and validate a novel method, DivE, to estimate species richness and distribution. We used three independent datasets: (i) viral populations from subjects infected with human T-lymphotropic virus type 1; (ii) T cell antigen receptor clonotype repertoires; and (iii) microbial data from infant faecal samples. When applied to datasets with rarefaction curves that did not plateau, existing estimators systematically increased with sample size. In contrast, DivE consistently and accurately estimated diversity for all datasets. We identify conditions that limit the application of DivE. We also show that DivE can be used to accurately estimate the underlying population frequency distribution. We have developed a novel method that is significantly more accurate than commonly used biodiversity estimators in microbiological and immunological populations. PMID:24945836

    2. Melucci e Tarrow: revisão teórica sobre movimentos sociais

      Directory of Open Access Journals (Sweden)

      Nayra Veras de Araújo

      2012-04-01

      Full Text Available <div>O campo empírico que envolve os movimentos sociais é amplo e diversificado, o que resulta na existência de uma multiplicidade de modelos teóricos e abordagens diferentes para interpretá-los. Este fato deriva do esforço de alguns teóricos em tentar esclarecer o que são os movimentos sociais, quais seus fundamentos, como se formam, quais suas características, seus componentes entre outros traços que os definem e os compõem. O objetivo do artigo é discutir a contribuição teórica de Sidney Tarrow e Alberto Melucci para o estudo dos movimentos sociais. Tal intento deve ser compreendido como interesse em partilhar as contribuições dos autores supracitados para o estudo analítico dos movimentos sociais e evidenciar que, apesar de situados em paradigmas distintos, seus pressupostos teóricos não estão completamente desligados. O diálogo será traçado com vistas a oferecer o panorama teóricodiv>>de análise de cada um dos autores: conceitos, categorias e abordagens div>

    3. Diversidade sexual e Política Nacional de Saúde Mental: contribuições pertinentes dos sujeitos insistentes

      Directory of Open Access Journals (Sweden)

      Marco José de Oliveira Duarte

      2012-04-01

      Full Text Available <div>  O presente artigo tem como objetivo problematizar algumas questões pertinentes para os estudos em diversidade sexual, tendo como ponto de pauta as relações entre o sofrimento mental, os direitos humanos de LGBT e a política pública de saúde mental para contemporizar e qualificar o público-alvo dos serviços de saúde mental. Toma como referência as representaçõesdiv>>sociais e culturais que instituíram esses sujeitos nos lugares próprios da patologia, do desvio, da segregação e da exclusão social e os atuais processos que se encontram na luta por direitos humanos e cidadania. Nesse contexto, apesar dos ditos avanços no campo dos direitos humanos, a experiência do sofrimento mental de LGBT é levada em consideração na perspectiva da pro-moção de equidade em saúde, a partir de suas vulnerabilidades específicas, mesmo sendo consenso no campo público e político da saúde, a necessidade de enfrentamento da homofobia e da transfobia.div>

    4. Universo canavieiro e reprodução das desigualdades sociais

      Directory of Open Access Journals (Sweden)

      Severina Garcia de Araújo

      2012-03-01

      Full Text Available <div>O artigo apresenta um estudo no âmbito da nova expansão da agro-indústria canavieira ante a política oficial de incentivo à matriz energética renovável, no contexto da mundialização do capital, sob direção do capital financeiro, que participa do capital produtivo e, juntos, avançam nos negóciosdiv>>da agricultura e no mercado de terras, agravando o processo de exploração/expropriação da força de trabalho e as desigualdades. O estudo expõe a crescente presença de grupos internacionais que, face ao grande número de traba-lhadores desempregados, recorrem à superexploração de sua força de trabalho, tida como escravidão moderna em termos jurídicos. Por meio do estudo, foi possível concluir que se trata de um dos mecanismos de acumulação por espoliação, próprio da dinâmica capitalista, de modo que o novo cenário revela o paradoxo entre expansão e lucratividade de um lado, pobreza e desigualdades do outro.div>

    5. Report on the activities of Space Science Department in 1978/1979

      International Nuclear Information System (INIS)

      Page, D.E.; Fitton, B.; Pedersen, A.; Taylor, B.G.; Wenzel, K.-P.

      1980-09-01

      In the chapters which follow each of the four Divisions, (Cosmic Ray Div., Space Plasma Div., Astronomy Div., and High Energy Astrophysic Div.) has described its work in the sequence: 'Support given to projects', 'Support given to studies', and 'Research activities'. The effort and time devoted to each area of work is by no means proportional to the length of text appearing in each area. Any attempt to fully describe support given to a project tends to result in what is merely a diary of meetings, tests, failures, re-scheduling efforts, repair of experiments, re-tests, compromise negotiation, inter-experimenter refereeing etc., and such diaries, although instructive, seemed inappropriate in this report. Reports on projects and studies therefore in general simply describe the project and say that it was supported. It should be mentioned, however, that major efforts, outside the normal role of SSD, have gone into the IUE and Exosat projects. The scientific operations of IUE were planned and are directed from the Astronomy Division to which the visiting scientists at Villafranca report. The design and production of the Exosat payload is being managed from the High Energy Astrophysics Division and plans are now being made for the operation of the Exosat Observatory and the distribution of the data

    6. A difícil incorporação conceitual do gênero: uma controversa perspectiva educacional

      Directory of Open Access Journals (Sweden)

      Dayse de Paula Marques da Silva

      2012-04-01

      Full Text Available <div>Há muita tensão hoje no campo educacional, pois a formação de novos valores e abordagens pedagógicas tem enfrentado uma crise de modelos e paradigmas que fragiliza em alguns momentos os educadores na sua tomada de decisão quanto a determinados preceitos éticos e filosóficos a serem resguardados na relação com os alunos. Esta questão sempre foi ambígua e expressou múltiplas abordagens no processo de formação educacional. A apresentação deste texto é resultado do desenvolvimento de pesquisas no campo das relações de gênero e educação, experiências em projetos dediv>>extensão e assessorias desenvolvidas no espaço escolar na perspectiva da prevenção da violência doméstica. O contato direto com professores, coordenadores pedagógicos e profissionais de outras áreas na escola motivou a sistematização de uma reflexão que colocasse em debate algumas tendências na abordagem do gênero e da sexualidade no espaço educacionaldiv>

    7. 31 CFR 595.315 - United States person; U.S. person.

      Science.gov (United States)

      2010-07-01

      ... (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY TERRORISM SANCTIONS REGULATIONS General Definitions § 595.315 United States person; U.S. person. The term United States person or U.S...

    8. Personality traits and chronic disease: implications for adult personality development.

      Science.gov (United States)

      Sutin, Angelina R; Zonderman, Alan B; Ferrucci, Luigi; Terracciano, Antonio

      2013-11-01

      Personality traits have been associated with chronic disease. Less is known about the longitudinal relation between personality and disease and whether chronic disease is associated with changes in personality. Method. Participants from the Baltimore Longitudinal Study of Aging (N = 2,008) completed the Revised NEO Personality Inventory and a standard medical interview at regularly scheduled visits; the Charlson Comorbidity Index, a weighted sum of 19 serious diseases, was derived from this interview. Using data from 6,685 visits, we tested whether personality increased risk of disease and whether disease was associated with personality change. Measured concurrently, neuroticism and conscientiousness were associated with greater disease burden. The impulsiveness facet of neuroticism was the strongest predictor of developing disease across the follow-up period: For every standard deviation increase in impulsiveness, there was a 26% increased risk of developing disease and a 36% increased risk of getting more ill. Personality traits changed only modestly with disease: As participants developed chronic illnesses, they became more conservative (decreased openness). Discussion. This research indicates that personality traits confer risk for disease, in part, through health-risk behaviors. These traits, however, were relatively resistant to the effect of serious disease.

    9. Personality in cyberspace: personal Web sites as media for personality expressions and impressions.

      Science.gov (United States)

      Marcus, Bernd; Machilek, Franz; Schütz, Astrid

      2006-06-01

      This research examined the personality of owners of personal Web sites based on self-reports, visitors' ratings, and the content of the Web sites. The authors compared a large sample of Web site owners with population-wide samples on the Big Five dimensions of personality. Controlling for demographic differences, the average Web site owner reported being slightly less extraverted and more open to experience. Compared with various other samples, Web site owners did not generally differ on narcissism, self-monitoring, or self-esteem, but gender differences on these traits were often smaller in Web site owners. Self-other agreement was highest with Openness to Experience, but valid judgments of all Big Five dimensions were derived from Web sites providing rich information. Visitors made use of quantifiable features of the Web site to infer personality, and the cues they utilized partly corresponded to self-reported traits. Copyright 2006 APA, all rights reserved.

    10. Personality and Euroscepticism

      DEFF Research Database (Denmark)

      Nielsen, Julie Hassing

      2016-01-01

      and openness positively correlate with positive EU attitudes, while people scoring high on neuroticism tend to support the EU less. Furthermore, I find that personality moderates different EU frames. Individuals with certain personality traits are more influenced by framing effects than others, while positive......Attitudes towards EU integration are widely studied, yet we know only little about the role of personality for EU attitudes. Utilizing a framing experiment encompassing positive and negative frames of EU integration, this article reports on how personality influences attitudes towards EU...... integration, and how personal predispositions moderate framing effects, impacting EU attitude formation. The study relies on Danish and Swedish data (N = 1808). I test both the direct impact of personality on EU attitudes and personality's moderating impact on framing effects. I find that extraversion...

    11. Confiabilidade de um método de análise histológica da degeneração discal experimental em coelhos Confiabilidad de un método para el análisis histológico de la degeneración discal experimental en conejos Reliability of a method for histological analysis of experimental disc degeneration in rabbits

      Directory of Open Access Journals (Sweden)

      Emiliano Neves Vialle

      2011-01-01

      Full Text Available OBJETIVO: Validar um método para avaliação histológica da degeneração discal experimental em coelhos, baseando-se na confiabilidade da análise interobservador. MÉTODOS: Treze coelhos da raça New Zealand foram submetidos a procedimento de indução da degeneração discal através de punção direta de três discos intervertebrais (DIV consecutivos com agulha 18G sob anestesia. Ao fim de dois meses, coletou-se a coluna vertebral completa de cada coelho e procedeu-se preparo das peças para análise histológica dos discos intervertebrais (Experimentais e Controle, sendo coradas pelo método hematoxilina-eosina. As lâminas histológicas foram avaliadas quanto à ocorrência de degeneração através da análise dos seguintes critérios: presença de vasos sanguíneos; presença de protrusão do núcleo pulposo (NP através do ânulo fibroso (AF; e ruptura das fibras do AF. RESULTADOS: Ao final dos processos de eutanásia, retirada da coluna e preparo histológico, obteve-se 60 DIV viáveis para avaliação de degeneração. Deste total, 25 peças eram de DIV experimentais e 35 peças de DIV controle. A presença de vaso sanguíneo foi observada em 18 dos 25 DIV degenerados, com concordância de Kappa = 0,95 entre os observadores. A presença da extrusão do NP foi identificada em 19 dos 25 DIV experimentais, com concordância de Kappa = 0,78 entre os observadores. Com relação à ruptura das fibras do AF, pode-se identificar a positividade em 24 dos 25 DIV degenerados, com concordância entre os observadores de Kappa = 0,65. CONCLUSÃO: Este modelo de avaliação histológica da degeneração experimental do DIV mostrou-se viável, com alto grau de concordância entre os observadores na identificação da degeneração discal.OBJETIVO: Validar un método para evaluación histológica de la degeneración discal experimental en conejos, basándose en la confiabilidad del análisis interobservadores. MÉTODOS: Trece conejos de la raza New

    12. Cortical mechanisms of person representation: recognition of famous and personally familiar names.

      Science.gov (United States)

      Sugiura, Motoaki; Sassa, Yuko; Watanabe, Jobu; Akitsuki, Yuko; Maeda, Yasuhiro; Matsue, Yoshihiko; Fukuda, Hiroshi; Kawashima, Ryuta

      2006-06-01

      Personally familiar people are likely to be represented more richly in episodic, emotional, and behavioral contexts than famous people, who are usually represented predominantly in semantic context. To reveal cortical mechanisms supporting this differential person representation, we compared cortical activation during name recognition tasks between personally familiar and famous names, using an event-related functional magnetic resonance imaging (fMRI). Normal subjects performed familiar- or unfamiliar-name detection tasks during visual presentation of personally familiar (Personal), famous (Famous), and unfamiliar (Unfamiliar) names. The bilateral temporal poles and anterolateral temporal cortices, as well as the left temporoparietal junction, were activated in the contrasts Personal-Unfamiliar and Famous-Unfamiliar to a similar extent. The bilateral occipitotemporoparietal junctions, precuneus, and posterior cingulate cortex showed activation in the contrasts Personal-Unfamiliar and Personal-Famous. Together with previous findings, differential activation in the occipitotemporoparietal junction, precuneus, and posterior cingulate cortex between personally familiar and famous names is considered to reflect differential person representation. The similar extent of activation for personally familiar and famous names in the temporal pole and anterolateral temporal cortex is consistent with the associative role of the anterior temporal cortex in person identification, which has been conceptualized as a person identity node in many models of person identification. The left temporoparietal junction was considered to process familiar written names. The results illustrated the neural correlates of the person representation as a network of discrete regions in the bilateral posterior cortices, with the anterior temporal cortices having a unique associative role.

    13. EFFECT OF ORGANIC AND INORGANIC MINERAL SUPPLEMENTATION ON SEMINAL QUALITY OF BOARS EXPOSED TO HEAT STRESS EFEITO DA SUPLEMENTAÇÃO DE MINERAIS ORGÂNICOS E INORGÂNICOS NA QUALIDADE DO SÊMEN DE SUÍNOS SUBMETIDOS A ESTRESSE TÉRMICO

      Directory of Open Access Journals (Sweden)

      Daiane Donin Spessatto

      2009-12-01

      Full Text Available <div>Seasonal high temperatures or inadequate nutrition can decrease reproductive efficiency in boars, especially through a reduction in spermatozoal number / ejaculate and percentage of normal spermatozoa. The aim of this study was to evaluate the effect of organic and inorganic trace mineral supplementation on seminal quality in boars exposed to high environmental temperatures. The experiment was conducted in Southern Brazil, west of Parana State. Boars (2 years of age were divided into three groups to receive: inorganic (GIn, n=4 and organic (GOr, n=4 mineral supplementation and a lactation diet (GCo, n=5. Inorganic and organic diets contained a premix of inorganic and organic trace minerals, respectively, with the same quantity of each trace mineral, based on NRC (NRC, 1998 for boars. The lactation diet was based on NRC for lactating sows and contained a higher level of inorganic trace minerals, protein and metabolic energy. Maximum mean environmental temperatures were higher than the normal thermal comfort temperature for boars (26oC during the experimental period, and were associated with a reduction in semen quality. Results are expressed as mean ± SEM. The semen volume of Inorganic and Organic diet groups were higher than Lactation group animals (345.7 ± 92.6 mL and 338.4 ± 67.8 mL versus 302.5 ± 81.4 mL, respectively; P=0.02. Boars in the Organic diet group had higher sperm concentration when compared to the Inorganic diet group (233.5 ± 76.7 X 106 sptz/mL versus 181.2 ± 77.3 X 106 sptz/mL, respectively; P=0.006. Percentage of normal spermatozoa, averaged higher in the Organic group than both Inorganic and Lactation groups (93.31 ± 5.20% versus 78.48 ± 12.15% and 82.59 ± 17.27%, respectively; P=0.00021. High temperatures (>34.5 oC reduced normal spermatozoa number in all groups, but with significant differences only in the Inorganic and Lactation groups (P=0.03. Organic minerals were benefic to seminal quality, reducing some of

    14. Personality Processes: Mechanisms by which Personality Traits “Get Outside the Skin”

      Science.gov (United States)

      Hampson, Sarah E.

      2011-01-01

      It is time to better understand why personality traits predict consequential outcomes, which calls for a closer look at personality processes. Personality processes are mechanisms that unfold over time to produce the effects of personality traits. They include reactive and instrumental processes that moderate or mediate the association between traits and outcomes. These mechanisms are illustrated here by a selection of studies of traits representing the three broad domains of personality and temperament: negative emotionality, positive emotionality, and constraint. Personality processes are studied over the short-term, as in event-sampling studies, and over the long-term, as in lifespan research. Implications of findings from the study of processes are considered for resolving issues in models of personality structure, improving and extending methods of personality assessment, and identifying targets for personality interventions. PMID:21740225

    15. Evaluation of Seedlings Gowth of Eucalyptus badjensis in Substrata from Composted Residues (Pulp and Paper Mill, Brewery Industry and Goat Dung Resíduos Industriais e Dejetos da Caprinocultura como Componentes de Substratos para Produção de Mudas de Eucalyptus badjensis

      Directory of Open Access Journals (Sweden)

      Shizuo Maeda

      2011-03-01

      Full Text Available <div>The aim of this work was to evaluate the seedling growth of Eucalyptus badjensis Beuzev. & Welch in substrata prepared from different residues: pulp and paper mill wastes (organic sludge and cellulose mill liquid alkaline liquor, brewery malt and also goat manure. The experiment was carried out in the seedlings nursery of the Embrapa Florestas, in Colombo, Paraná. The organic sludge, cellulose mill liquid alkaline liquor and the brewer’s grain were previously composted with sawdust, and goat dung with pinus bark. A randomized blocks design with split-plot arrangement, with four replications was used. Plot treatments were the substrata and split-plot were base fertilization (with and without: 1 mixture of a commercial substratum prepared with composted pinus bark in a volume/volume relation - v/v - of 1/1 - standard of the experiment when base fertilization was applied; 2 composted brewery malt with sawdust in a relation v/v of 1/4; 3 composted organic sludge with sawdust (relation v/v of 1/1; 4 mixture ofdiv>>treatment 3 with pinus bark (relation v/v of 1/1; 5 composted cellulose mill liquid alkaline waste with sawdust (relation v/v of 4/1; 6 composted cellulose mill liquid alkaline waste with sawdust (relation v/v of 3/2; 7 mixture of the productdiv>>of treatment 6 with Pinus bark (relation v/v of 1/1; 8 composted goat dung with pinus bark. The results showed that substrata of treatments 2 and 8 can be used for the production of E. badjensis seedlings, with or without base fertilization, while treatment 4 can only be used with base fertilization. The growth of E. badjensis in the substratum of the standard treatment was not influenced by the lack of base fertilization.div>>Com o objetivo de avaliar resíduos gerados nas produções de papel e celulose, de cerveja e na caprinocultura como substratos para a produção de mudas de Eucalyptus badjensis Beuzev. & Welch, foi

    16. Predicting Personality Disorder Functioning Styles by the Five-Factor Nonverbal Personality Questionnaire in Healthy Volunteers and Personality Disorder Patients.

      Science.gov (United States)

      Gao, Qianqian; Ma, Guorong; Zhu, Qisha; Fan, Hongying; Wang, Wei

      2016-01-01

      Detecting personality disorders in the illiterate population is a challenge, but nonverbal tools measuring personality traits such as the Five-Factor Nonverbal Personality Questionnaire (FFNPQ) might help. We hypothesized that FFNPQ traits are associated with personality disorder functioning styles in a predictable way, especially in a sample of personality disorder patients. We therefore invited 106 personality disorder patients and 205 healthy volunteers to answer the FFNPQ and the Parker Personality Measure (PERM) which measures 11 personality disorder functioning styles. Patients scored significantly higher on the FFNPQ neuroticism and conscientiousness traits and all 11 PERM styles. In both groups, the 5 FFNPQ traits displayed extensive associations with the 11 PERM styles, respectively, and the associations were more specific in patients. Associations between neuroticism, extraversion and agreeableness traits and most PERM styles were less exclusive, but conscientiousness was associated with antisocial (-) and obsessive-compulsive styles, and openness to experience with schizotypal and dependent (-) styles. Our study has demonstrated correlations between FFNPQ traits and PERM styles, and implies the nonverbal measure of personality traits is capable of aiding the diagnoses of personality disorders in the illiterate population. Enlarging sample size and including the illiterate might make for more stable results. © 2016 S. Karger AG, Basel.

    17. The Social Cognitive Theory of Personality in the Context of Personal Marketing

      OpenAIRE

      Zvjezdana Penava Brekalo

      2010-01-01

      The starting point of personal marketing is an individual, i.e. a person. Personal marketing, in the sense of the narrowest level of marketing, has a markedly interdisciplinary character, because it relies on the knowledge of psychology - the science of psychological characteristics of a person. Psychological factors of personal marketing, like personality, behaviour, emotions, temperament, character and intelligence are numerous, but in this paper some of the psychological catego...

    18. Sociogenomic Personality Psychology

      Science.gov (United States)

      Roberts, Brent W.; Jackson, Joshua J.

      2009-01-01

      In this article, we address a number of issues surrounding biological models of personality traits. Most traditional and many contemporary biological models of personality traits assume that biological systems underlying personality traits are causal and immutable. In contrast, sociogenomic biology, which we introduce to readers in this article, directly contradicts the widely held assumption that something that is biological, heritable, or temperamental, is unchangeable. We provide examples of how seemingly unchanging biological systems, such as DNA, are both dependent on environments for elicitation and can be modified by environmental changes. Finally, we synthesize sociogenomic biology with personality psychology in a model of personality traits that integrates this more modern perspective on biology, physiology, and environment that we term sociogenomic personality psychology. We end the article with a discussion of the future directions of sociogenomic personality psychology. PMID:19012657

    19. In-home use of personalized music for persons with dementia.

      Science.gov (United States)

      Kulibert, Danica; Ebert, Alexandria; Preman, Sharayah; McFadden, Susan H

      2018-01-01

      Although evidence is mounting that personalized music has beneficial effects for long-term care residents with dementia, little research has examined the effects of personalized music for the majority of persons with dementia living at home. These individuals live at home with care partners who may also benefit from having music that is personalized for their loved one. Using the Music & Memory SM program of personalized playlists delivered via iPod Shuffles®, the current study examined the effects of the Music & Memory program for persons with dementia by using the Bath Assessment of Subjective Quality of Life in Dementia scale and a Music Listening Experience Scale developed for this study. We also administered three scales that captured care partner experiences. Transcripts of the Bath Assessment of Subjective Quality of Life in Dementia administrations at the beginning of the study and 3 months later, plus interviews about the Music & Memory program, were then analyzed using the interpretive phenomenological analysis method. Themes about the Music & Memory program and life living with dementia for from diagnosed persons and their care partners are discussed.

    20. Personal style of the therapist, attachment style and personality trait

      Directory of Open Access Journals (Sweden)

      Gabriel Genise

      2015-12-01

      Full Text Available The aim of this study is to analyze the relationship between the personal style of the therapist, attachment style and personality trait. It was used the personal style of the therapist questionnaire (PST – Q, the Argentinean attachment inventory and the big five inventory. The study sample consisted of 120 psychotherapists average age of 36.28 years (SD = 9.65, and the average years of experience was 7.90 years (SD = 8.04. The analysis of the results showed that there is a positive, significant and low intensity between the personality factor of openness to experience and personal style of involvement, a negative correlation, significant and of medium intensity between low extraversion factor correlation and mode not anxious romantic attachment and a significant positive relationship between the low–intensity factor neuroticism personality and how anxious romantic attachment. 

    1. Galvanic corrosion of structural non-stoichiometric silicon nitride thin films and its implications on reliability of microelectromechanical devices

      Energy Technology Data Exchange (ETDEWEB)

      Broas, M., E-mail: mikael.broas@aalto.fi; Mattila, T. T.; Paulasto-Kröckel, M. [Department of Electrical Engineering and Automation, Aalto University, Espoo, P.O. Box 13500, FIN-00076 Aalto (Finland); Liu, X.; Ge, Y. [Department of Materials Science and Engineering, Aalto University, Espoo, P.O. Box 16200, FIN-00076 Aalto (Finland)

      2015-06-28

      This paper describes a reliability assessment and failure analysis of a poly-Si/non-stoichiometric silicon nitride thin film composite structure. A set of poly-Si/SiN{sub x} thin film structures were exposed to a mixed flowing gas (MFG) environment, which simulates outdoor environments, for 90 days, and an elevated temperature and humidity (85 °C/95% R.H.) test for 140 days. The mechanical integrity of the thin films was observed to degrade during exposure to the chemically reactive atmospheres. The degree of degradation was analyzed with nanoindentation tests. Statistical analysis of the forces required to initiate a fracture in the thin films indicated degradation due to the exposure to the MFG environment in the SiN{sub x} part of the films. Scanning electron microscopy revealed a porous-like reaction layer on top of SiN{sub x}. The morphology of the reaction layer resembled that of galvanically corroded poly-Si. Transmission electron microscopy further clarified the microstructure of the reaction layer which had a complex multi-phase structure extending to depths of ∼100 nm. Furthermore, the layer was oxidized two times deeper in a 90 days MFG-tested sample compared to an untested reference. The formation of the layer is proposed to be caused by galvanic corrosion of elemental silicon in non-stoichiometric silicon nitride during hydrofluoric acid etching. The degradation is proposed to be due uncontrolled oxidation of the films during the stress tests.

    2. Personal disclosure revisited.

      Science.gov (United States)

      Olarte, Silvia W

      2003-01-01

      In this paper personal disclosure is defined as a conscious verbal presentation to the patient by the therapist of a personal vignette accompanied by the appropriate dynamic formulation and resolution of a given personal area of conflict. It is conceptualized within theoretical formulations which consider the therapeutic relationship a dyad, where the reality of the patient and the reality of the therapist influence each other, providing the matrix through which the resolution of the patient's past life experiences takes place in the context of this new interpersonal experience. It is specifically differentiated from a boundary violation, because the personal disclosure is brought to the patient's interactional awareness not for gratification of the therapist's sexual or narcissistic needs, but to provoke a response in the patient's conceptualization of a phenomenon being presented in the session and to actively influence the intersubjective field. Within the conceptual framework developed in this paper, personal disclosure reaffirms the patient's current self-discovery and provides for a different formative experience. Personal disclosure is not to be used by the therapist as a vehicle to resolve personal conflicts or as source of personal gratification. When used within the context developed in this paper, personal disclosure enhances both the patient's therapeutic process and the therapist's ever-evolving growth.

    3. Personality Diagnosis for Personalized eHealth Services

      Science.gov (United States)

      Cortellese, Fabio; Nalin, Marco; Morandi, Angelica; Sanna, Alberto; Grasso, Floriana

      In this paper we present two different approaches to personality diagnosis, for the provision of innovative personalized services, as used in a case study where diabetic patients were supported in the improvement of physical activity in their daily life. The first approach presented relies on a static clustering of the population, with a specific motivation strategy designed for each cluster. The second approach relies on a dynamic population clustering, making use of recommendation systems and algorithms, like Collaborative Filtering. We discuss pro and cons of each approach and a possible combination of the two, as the most promising solution for this and other personalization services in eHealth.

    4. Evaluation of Root Canal Morphology of Human Primary Mandibular ...

      African Journals Online (AJOL)

      2018-04-04

      Apr 4, 2018 ... Keywords: Primary teeth, root canal, Vertucci classification. Evaluation of Root .... Radiology using CBCT; Veraviewepocs 3D R100/F40. (J Morita Mfg. Corp., .... maxillofacial structures by CBCT on a high resolution, and this ...

    5. Personalized Regenerative Medicine

      Directory of Open Access Journals (Sweden)

      Babak Arjmand

      2017-03-01

      Full Text Available Personalized medicine as a novel field of medicine refers to the prescription of specific therapeutics procedure for an individual. This approach has established based on pharmacogenetic and pharmacogenomic information and data. The terms precision and personalized medicines are sometimes applied interchangeably. However, there has been a shift from “personalized medicine” towards “precision medicine”. Although personalized medicine emerged from pharmacogenetics, nowadays it covers many fields of healthcare. Accordingly, regenerative medicine and cellular therapy as the new fields of medicine use cell-based products in order to develop personalized treatments. Different sources of stem cells including mesenchymal stem cells, embryonic stem cells and induced pluripotent stem cells (iPSCs have been considered in targeted therapies which could give many advantages. iPSCs as the novel and individual pluripotent stem cells have been introduced as the appropriate candidates for personalized cell therapies. Cellular therapies can provide a personalized approach. Because of person-to-person and population differences in the result of stem cell therapy, individualized cellular therapy must be adjusted according to the patient specific profile, in order to achieve best therapeutic results and outcomes. Several factors should be considered to achieve personalized stem cells therapy such as, recipient factors, donor factors, and the overall body environment in which the stem cells could be active and functional. In addition to these factors, the source of stem cells must be carefully chosen based on functional and physical criteria that lead to optimal outcomes.

    6. Myopia and personality: the genes in myopia (GEM) personality study.

      Science.gov (United States)

      van de Berg, Robert; Dirani, Mohamed; Chen, Christine Y; Haslam, Nicholas; Baird, Paul N

      2008-03-01

      A long-held view among the medical and broader community is that people who are short-sighted (myopic persons) have distinctive personality characteristics such as introversion and conscientiousness. However, existing research on this question is flawed, and its findings are inconsistent. The authors therefore aimed to determine whether myopia and personality are associated. The authors examined twins recruited through the Australian Twin Registry and a clinical-based family sample through a proband from a Melbourne Excimer Laser Clinic. There was no relation between family members and twins recruited in our study. Each individual underwent a full eye examination, completed a standard medical and general questionnaire, and was administered a five-factor model International Personality Item Pool (IPIP) inventory (Openness, Conscientiousness, Extroversion, Agreeableness, Neuroticism). Myopia was defined as worse than or equal to -0.50 (DS) spherical equivalent in the eye with the least refractive error. Data from 633 individual twins aged 18 to 83 years (mean, 53.04 years) and 278 family members aged 11 to 90 years (mean, 49.84 years) were analyzed. Prevalence of myopia was 35.7% for twins and 47.6% for family members. Mean spherical equivalent was +0.13 DS (95% CI, +/-0.16) for twins and -1.13 DS (95% CI, +/-0.25) for family members. Correlation and regression results for personality for both sample cohorts after multivariate analysis did not support the view that myopic persons are introverted or conscientious; however, there was a significant but small association between myopia and Agreeableness (r = 0.08, P personality factors entered as predictors, Openness was the only significant personality predictor of myopia in both samples. This is the first multivariate study to assess links between personality and myopia using the IPIP. The long-held view that myopic persons are introverted and conscientious may reflect intelligence-related stereotypes rather than real

    7. Hearing Aid Personalization

      DEFF Research Database (Denmark)

      Nielsen, Jens Brehm; Nielsen, Jakob; Jensen, Bjørn Sand

      2013-01-01

      Modern digital hearing aids require and offer a great level of personalization. Today, this personalization is not performed based directly on what the user actually perceives, but on a hearing-care professional’s interpretation of what the user explains about what is perceived. In this paper......, an interactive personalization system based on Gaussian process regression and active learning is proposed, which personalize the hearing aids based directly on what the user perceives. Preliminary results demonstrate a significant difference between a truly personalized setting obtained with the proposed system...

    8. The Schedule for Nonadaptive and Adaptive Personality for Youth (SNAP-Y): a new measure for assessing adolescent personality and personality pathology.

      Science.gov (United States)

      Linde, Jennifer A; Stringer, Deborah; Simms, Leonard J; Clark, Lee Anna

      2013-08-01

      The Schedule for Nonadaptive and Adaptive Personality-Youth Version (SNAP-Y) is a new, reliable self-report questionnaire that assesses 15 personality traits relevant to both normal-range personality and the alternative DSM-5 model for personality disorder. Community adolescents, 12 to 18 years old (N = 364), completed the SNAP-Y; 347 also completed the Big Five Inventory-Adolescent, 144 provided 2-week retest data, and 128 others completed the Minnesota Multiphasic Personality Inventory-Adolescent. Outpatient adolescents (N = 103) completed the SNAP-Y, and 97 also completed the Minnesota Multiphasic Personality Inventory-Adolescent. The SNAP-Y demonstrated strong psychometric properties, and structural, convergent, discriminant, and external validities. Consistent with the continuity of personality, results paralleled those in adult and college samples using the adult Schedule for Nonadaptive and Adaptive Personality-Second Edition (SNAP-2), from which the SNAP-Y derives and which has established validity in personality-trait assessment across the normal-abnormal continuum. The SNAP-Y thus provides a new, clinically useful instrument to assess personality traits and personality pathology in adolescents.

    9. IMPLEMENTATION OF THE NEW CAREER STRUCURE SCHEME (MAPS)

      CERN Multimedia

      HR Division

      2002-01-01

      As indicated in the CERN Bulletin 4/2002, following the completion of the divisional seminars, divisions may start their annual interviews on a top-down basis which must be completed by end-March 2002. The new annual interview report form template is available on the HR Division website. A banner on the internal homepage : http://cern.ch/hr-div leads directly to the page with our administrative forms. It is also now being installed as a Nice template. During the course of next week, the personal data for the first page can be generated via HRT and Divisional Administrative Officers have been advised on how divisions can use this new process. HR Division Tel. 74480

    10. The Entrepreneurial Personalities

      DEFF Research Database (Denmark)

      Østergaard, Annemarie

      The objective of the research is to investigate what constitutes the entrepreneurial personality in terms of innate and learned personality characteristics and how these relate to environmental impact and leadership. The thesis argues that an entrepreneurial personality is a combination of traits......-driven conceptualization, data were collected from 55 active entrepreneurs’ primarily located in Nupark, Holstebro, in Denmark. The selected population of entrepreneurs completed a 2-hour standardised and validated personality test measuring 36 personality traits, a leadership preference test with 27 leadership roles...... is described according to the empirical findings. Furthermore, the research finds that the set of personality traits necessary for an entrepreneur consists of Autonomy, Exploration Drive, Preparedness for Change, and Self-preservation Instinct. In conclusion, to answer the research question regarding...

    11. Person-Oriented Conception of Happiness and Some Personality Theories

      Directory of Open Access Journals (Sweden)

      Leonid Z. Levit

      2014-01-01

      Full Text Available Person-oriented conception of happiness (POCH worked out by the author of the article is based on the ideas of systemic approach. The model also serves as valuable personality theory integrating essential elements of the conceptions of Z. Freud, C. Jung, A. Maslow, C. Rogers, and some other scientists. We show how to solve some problems of modern psychology within POCH, and outline perspectives of further investigations. For the first time in world psychology, such concepts as “Egoism” and “Personal Uniqueness” are represented as multilevel systems. Their productive interaction at the higher levels helps a person achieve full-fledged, happy life.

    12. Parents' personality clusters and eating disordered daughters' personality and psychopathology.

      Science.gov (United States)

      Amianto, Federico; Ercole, Roberta; Marzola, Enrica; Abbate Daga, Giovanni; Fassino, Secondo

      2015-11-30

      The present study explores how parents' personality clusters relate to their eating disordered daughters' personality and psychopathology. Mothers and fathers were tested with the Temperament Character Inventory. Their daughters were assessed with the following: Temperament and Character Inventory, Eating Disorder Inventory-2, Symptom Checklist-90, Parental Bonding Instrument, Attachment Style Questionnaire, and Family Assessment Device. Daughters' personality traits and psychopathology scores were compared between clusters. Daughters' features were related to those of their parents. Explosive/adventurous mothers were found to relate to their daughters' borderline personality profile and more severe interoceptive awareness. Mothers' immaturity was correlated to their daughters' higher character immaturity, inadequacy, and depressive feelings. Fathers who were explosive/methodic correlated with their daughters' character immaturity, severe eating, and general psychopathology. Fathers' character immaturity only marginally related to their daughters' specific features. Both parents' temperament clusters and mothers' character clusters related to patients' personality and eating psychopathology. The cluster approach to personality-related dynamics of families with an individual affected by an eating disorder expands the knowledge on the relationship between parents' characteristics and daughters' illness, suggesting complex and unique relationships correlating parents' personality traits to their daughters' disorder. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

    13. Immunochemical expression of proliferative cell nuclear antigen in aging cultured astrocytes

      Directory of Open Access Journals (Sweden)

      M. C. Vanzani

      2003-08-01

      Full Text Available Cell differentiation degree and mitotic activity were sequentially assessed by immunoperoxidase labeling of glial fibrillary acidic protein (GFAP and proliferative cell nuclear antigen (PCNA, respectively, in rat brain cultured astrocytes maintained up to 60 days in vitro (DIV of first subculture, or weekly passaged until their 12th subculture. Cell count was performed through a 0.01 mm2 section reticule and morphometric analysis with a stereological grid. The number of double immunoreactive cells peaked by 2 DIV to achieve its lowest value at 60 DIV. At 24 hs of cell seeding of successive passages, such values peaked by the 6th subculture to gradually decrease thereafter. Increasing cell hypertrophy was found during the long-term first subculture but not after passaging. At the end of the observation period, doubly immunolabeled astrocytes were still recorded, thus evidencing retention of proliferative potential despite aging.El grado de diferenciación celular y la actividad mitótica fueron secuencialmente determinados mediante marcación por inmunoperoxidasa de la proteína gliofibrilar ácida (GFAP y del antígeno nuclear de proliferación celular (PCNA, respectivamente, en cultivos astrocitarios obtenidos de encéfalo de rata y mantenidos hasta 60 días in vitro (DIV de su primer subcultivo, o mediante pasajes semanales hasta el 12do subcultivo. El conteo celular se realizó mediante una retícula de 0.01-mm2 de sección y el análisis morfométrico con una grilla estereológica. El número de células doblemente inmunorreactivas alcanzó valores máximos a los 2 DIV para descender a los menores a los 60 DIV. A las 24 hs de sembrado celular de los sucesivos pasajes, esos valores ascendieron hacia el 6to subcultivo para luego declinar. En cuanto a la hipertrofia celular, se observó en todo el curso del primer subcultivo, pero no durante los posteriores pasajes. Al final del período de observación, todavía se continuaban detectando

    14. Biclustered Independent Component Analysis for Complex Biomarker and Subtype Identification from Structural Magnetic Resonance Images in Schizophrenia

      Directory of Open Access Journals (Sweden)

      Cota Navin Gupta

      2017-09-01

      Full Text Available Clinical and cognitive symptoms domain-based subtyping in schizophrenia (Sz has been critiqued due to the lack of neurobiological correlates and heterogeneity in symptom scores. We, therefore, present a novel data-driven framework using biclustered independent component analysis to detect subtypes from the reliable and stable gray matter concentration (GMC of patients with Sz. The developed methodology consists of the following steps: source-based morphometry (SBM decomposition, selection and sorting of two component loadings, subtype component reconstruction using group information-guided ICA (GIG-ICA. This framework was applied to the top two group discriminative components namely the insula/superior temporal gyrus/inferior frontal gyrus (I-STG-IFG component and the superior frontal gyrus/middle frontal gyrus/medial frontal gyrus (SFG-MiFG-MFG component from our previous SBM study, which showed diagnostic group difference and had the highest effect sizes. The aggregated multisite dataset consisted of 382 patients with Sz regressed of age, gender, and site voxelwise. We observed two subtypes (i.e., two different subsets of subjects each heavily weighted on these two components, respectively. These subsets of subjects were characterized by significant differences in positive and negative syndrome scale (PANSS positive clinical symptoms (p = 0.005. We also observed an overlapping subtype weighing heavily on both of these components. The PANSS general clinical symptom of this subtype was trend level correlated with the loading coefficients of the SFG-MiFG-MFG component (r = 0.25; p = 0.07. The reconstructed subtype-specific component using GIG-ICA showed variations in voxel regions, when compared to the group component. We observed deviations from mean GMC along with conjunction of features from two components characterizing each deciphered subtype. These inherent variations in GMC among patients with Sz could possibly indicate the

    15. Sensitivity Analysis of Personal Exposure Assessment Using a Computer Simulated Person

      DEFF Research Database (Denmark)

      Brohus, Henrik; Jensen, H. K.

      2009-01-01

      The paper considers uncertainties related to personal exposure assessment using a computer simulated person. CFD is used to simulate a uniform flow field around a human being to determine the personal exposure to a contaminant source. For various vertical locations of a point contaminant source...... three additional factors are varied, namely the velocity, details of the computer simulated person, and the CFD model of the wind channel. The personal exposure is found to be highly dependent on the relative source location. Variation in the range of two orders of magnitude is found. The exposure...

    16. Electromagnetic Pulse/Transient Threat Testing of Protection Devices for Amateur/Military Affiliate Radio System Equipment. Volume 3. Test Data, Electromagnetic Pulse Testing of Protection Devices. Section 1. High Energy Pulse-Device Failure Test. 50 Ohms Impedance 25,000 Volts-4000 Amps, 100 Joules.

      Science.gov (United States)

      1985-10-31

      7 oat s LinkI . . - P Comments: ~ y V ,~o.*.-’ ,. 157q Pk: 6ETtC*6L- - ’ . */-’-..- -,.-., Oats Teet Poit c C 2 b AmplifI481OS’ dS Attenuaio 2-4D dB...Puleer Level * Data LinkI Comments: /:2- VO%’ a*1 Date/3 - Attenuaion dS HMmontai na/dIv I Vertial mnV/div I s. Horizontal g n a/div 2 Vertical IV

    17. Sizing up countability

      OpenAIRE

      De Belder, Marijke

      2008-01-01

      SIZING UP COUNTABILITY: TOWARDS A MORE FINE-GRAINED MASS-COUNT DISTINCTION MARIJKE DE BELDER CRISSP/CATHOLIC UNIVERSITY OF BRUSSELS/FACULTÉS UNIVERSITAIRES SAINT-LOUIS 1. Summary Borer (2005) argues that the presence of the functional projection DivP, which divides stuff into units, yields count readings in the NP and that its absence yields mass readings. I claim, however, that countability requires not only DivP (which creates units) but also SizeP (which assigns size). The head ...

    18. The big seven model of personality and its relevance to personality pathology.

      Science.gov (United States)

      Simms, Leonard J

      2007-02-01

      Proponents of the Big Seven model of personality have suggested that Positive Valence (PV) and Negative Valence (NV) are independent of the Big Five personality dimensions and may be particularly relevant to personality disorder. These hypotheses were tested with 403 undergraduates who completed a Big Seven measure and markers of the Big Five and personality pathology. Results revealed that PV and NV incrementally predicted personality pathology dimensions beyond those predicted by multiple markers of the Big Five. However, factor analyses suggested that PV and NV might be best understood as specific, maladaptive aspects of positive emotionality and low agreeableness, respectively, as opposed to independent factors of personality. Implications for the description of normal and abnormal personality are discussed.

    19. Is Personalized Communication Superior? Personalization and Consumers’ Characteristics

      NARCIS (Netherlands)

      Maslowska, E.; Smit, E.G.; van den Putte, B.

      2011-01-01

      Personalized communication has become a very popular marketing strategy, but the research on its effectiveness is still limited. This study examined the effectiveness of personalized digital newsletters in terms of increased attention, evaluation, attitude, and intention. Participants (N = 124) were

    20. Personality functioning in patients with avoidant personality disorder and social phobia.

      Science.gov (United States)

      Eikenaes, Ingeborg; Hummelen, Benjamin; Abrahamsen, Gun; Andrea, Helene; Wilberg, Theresa

      2013-12-01

      Avoidant personality disorder (APD) and social phobia (SP) are closely related, such that they are suggested to represent different severity levels of one social anxiety disorder. This cross-sectional study aimed to compare patients with APD to patients with SP, with particular focus on personality dysfunction. Ninety-one adult patients were examined by diagnostic interviews and self-report measures, including the Index of Self-Esteem and the Severity Indices of Personality Problems. Patients were categorized in three groups; SP without APD (n = 20), APD without SP (n = 15), and APD with SP (n = 56). Compared to patients with SP without APD, patients with APD reported more symptom disorders, psychosocial problems, criteria of personality disorders, and personality dysfunction regarding self-esteem, identity and relational problems. These results indicate that APD involves more severe and broader areas of personality dysfunction than SP, supporting the conceptualization of APD as a personality disorder as proposed for DSM-5.

    1. Identification of Ser/Thr kinase and Forkhead Associated Domains in Mycobacterium ulcerans: Characterization of Novel Association between Protein Kinase Q and MupFHA

      Science.gov (United States)

      Singhal, Anshika; Joshi, Jayadev; Virmani, Richa; Gupta, Meetu; Verma, Nupur; Maji, Abhijit; Misra, Richa; Baronian, Grégory; Pandey, Amit K.; Molle, Virginie; Singh, Yogendra

      2014-01-01

      Background Mycobacterium ulcerans, the causative agent of Buruli ulcer in humans, is unique among the members of Mycobacterium genus due to the presence of the virulence determinant megaplasmid pMUM001. This plasmid encodes multiple virulence-associated genes, including mup011, which is an uncharacterized Ser/Thr protein kinase (STPK) PknQ. Methodology/Principal Findings In this study, we have characterized PknQ and explored its interaction with MupFHA (Mup018c), a FHA domain containing protein also encoded by pMUM001. MupFHA was found to interact with PknQ and suppress its autophosphorylation. Subsequent protein-protein docking and molecular dynamic simulation analyses showed that this interaction involves the FHA domain of MupFHA and PknQ activation loop residues Ser170 and Thr174. FHA domains are known to recognize phosphothreonine residues, and therefore, MupFHA may be acting as one of the few unusual FHA-domain having overlapping specificity. Additionally, we elucidated the PknQ-dependent regulation of MupDivIVA (Mup012c), which is a DivIVA domain containing protein encoded by pMUM001. MupDivIVA interacts with MupFHA and this interaction may also involve phospho-threonine/serine residues of MupDivIVA. Conclusions/Significance Together, these results describe novel signaling mechanisms in M. ulcerans and show a three-way regulation of PknQ, MupFHA, and MupDivIVA. FHA domains have been considered to be only pThr specific and our results indicate a novel mechanism of pSer as well as pThr interaction exhibited by MupFHA. These results signify the need of further re-evaluating the FHA domain –pThr/pSer interaction model. MupFHA may serve as the ideal candidate for structural studies on this unique class of modular enzymes. PMID:25412098

    2. Identification of Ser/Thr kinase and forkhead associated domains in Mycobacterium ulcerans: characterization of novel association between protein kinase Q and MupFHA.

      Directory of Open Access Journals (Sweden)

      Gunjan Arora

      2014-11-01

      Full Text Available Mycobacterium ulcerans, the causative agent of Buruli ulcer in humans, is unique among the members of Mycobacterium genus due to the presence of the virulence determinant megaplasmid pMUM001. This plasmid encodes multiple virulence-associated genes, including mup011, which is an uncharacterized Ser/Thr protein kinase (STPK PknQ.In this study, we have characterized PknQ and explored its interaction with MupFHA (Mup018c, a FHA domain containing protein also encoded by pMUM001. MupFHA was found to interact with PknQ and suppress its autophosphorylation. Subsequent protein-protein docking and molecular dynamic simulation analyses showed that this interaction involves the FHA domain of MupFHA and PknQ activation loop residues Ser170 and Thr174. FHA domains are known to recognize phosphothreonine residues, and therefore, MupFHA may be acting as one of the few unusual FHA-domain having overlapping specificity. Additionally, we elucidated the PknQ-dependent regulation of MupDivIVA (Mup012c, which is a DivIVA domain containing protein encoded by pMUM001. MupDivIVA interacts with MupFHA and this interaction may also involve phospho-threonine/serine residues of MupDivIVA.Together, these results describe novel signaling mechanisms in M. ulcerans and show a three-way regulation of PknQ, MupFHA, and MupDivIVA. FHA domains have been considered to be only pThr specific and our results indicate a novel mechanism of pSer as well as pThr interaction exhibited by MupFHA. These results signify the need of further re-evaluating the FHA domain -pThr/pSer interaction model. MupFHA may serve as the ideal candidate for structural studies on this unique class of modular enzymes.

    3. Differentiating normal and disordered personality using the General Assessment of Personality Disorder (GAPD).

      Science.gov (United States)

      Hentschel, Annett G; John Livesley, W

      2013-05-01

      Criteria to differentiate personality disorder from extremes of normal personality variations are important given growing interest in dimensional classification because an extreme level of a personality dimension does not necessarily indicate disorder. The DSM-5 proposed classification of personality disorder offers a definition of general personality disorder based on chronic interpersonal and self/identity pathology. The ability of this approach to differentiate personality disorder from other mental disorders was evaluated using a self-report questionnaire, the General Assessment of Personality Disorder (GAPD). This measure was administered to a sample of psychiatric patients (N = 149) from different clinical sub-sites. Patients were divided into personality disordered and non-personality disordered groups on the basis of the Structured Clinical Interview for DSM-IV Axis II Disorders (SCID-II). The results showed a hit rate of 82% correct identified patients and a good accuracy of the predicted model. There was a substantial agreement between SCID-II interview and GAPD personality disorder diagnoses. The GAPD appears to predict personality disorder in general, which provides support of the DSM-5 general diagnostic criteria of personality disorder. Copyright © 2012 John Wiley & Sons, Ltd.

    4. Clinical Components of Borderline Personality Disorder and Personality Functioning.

      Science.gov (United States)

      Ferrer, Marc; Andión, Óscar; Calvo, Natalia; Hörz, Susanne; Fischer-Kern, Melitta; Kapusta, Nestor D; Schneider, Gudrun; Clarkin, John F; Doering, Stephan

      2018-01-01

      Impairment in personality functioning (PF) represents a salient criterion of the DSM-5 alternative diagnostic model for personality disorders (AMPD). The main goal of this study is to analyze the relationship of the borderline personality disorder (BPD) clinical components derived from the DSM-5 categorical diagnostic model (affective dysregulation, behavioral dysregulation, and disturbed relatedness) with personality organization (PO), i.e., PF, assessed by the Structured Interview of Personality Organization (STIPO). STIPO and the Structured Clinical Interviews for DSM-IV (SCID-I and -II) were administered to 206 BPD patients. The relationship between PO and BPD components were studied using Spearman correlations and independent linear regression analyses. Significant positive correlations were observed between STIPO scores and several DSM-5 BPD criteria and comorbid psychiatric disorders. STIPO dimensions mainly correlated with disturbed relatedness and, to a lesser extent, affective dysregulation components. Each BPD clinical component was associated with specific STIPO dimensions. Both diagnostic models, DSM-5 BPD criteria and PO, are not only related but complementary concepts. The results of this study particularly recommend STIPO for the assessment of relational functioning, which is a major domain of the Personality Functioning Scale Levels of the DSM-5 AMPD. © 2018 S. Karger AG, Basel.

    5. Person Recognition in Personal Photo Collections

      OpenAIRE

      Oh, Seong Joon; Benenson, Rodrigo; Fritz, Mario; Schiele, Bernt

      2015-01-01

      Recognising persons in everyday photos presents major challenges (occluded faces, different clothing, locations, etc.) for machine vision. We propose a convnet based person recognition system on which we provide an in-depth analysis of informativeness of different body cues, impact of training data, and the common failure modes of the system. In addition, we discuss the limitations of existing benchmarks and propose more challenging ones. Our method is simple and is built on open source and o...

    6. 78 FR 13626 - Wooden Bedroom Furniture From the People's Republic of China: Initiation of Administrative Review

      Science.gov (United States)

      2013-02-28

      .... Shanghai Fangjia Industry Co., Ltd.... No. Shanghai Hospitality Product Mfg., No. Co., Ltd. Shanghai... Co., Ltd., Artwork Metal & Plastic Co., Ltd., Jibson Industries Ltd., Always Loyal International.... Taicang Sunrise Wood Industry Co., Ltd., Taicang Fairmount Designs Furniture Co., Ltd., Meizhou Sunrise...

    7. Decision-making deficits in normal elderly persons associated with executive personality disturbances.

      Science.gov (United States)

      Nguyen, Christopher M; Barrash, Joseph; Koenigs, Anna L; Bechara, Antoine; Tranel, Daniel; Denburg, Natalie L

      2013-11-01

      The problems that some community-dwelling elderly persons develop in real-world decision-making may have disastrous consequences for their health and financial well-being. Investigations across the adult life span have identified personality as an important individual differences variable that is related to decision-making ability. The aim of this study was to investigate the relationship between personality characteristics, as rated by an informant, and complex decision-making performance among elderly persons. It was hypothesized that deficits in decision-making would be associated with personality characteristics reflecting weak executive functioning (Lack of Planning, Poor Judgment, Lack of Persistence, Perseveration, Lack of Initiative, Impulsivity, and Indecisiveness). Fifty-eight elderly persons participated. Their health and cognitive status were deemed intact via comprehensive neuropsychological evaluation. The Iowa Scales of Personality, completed by an informant, was used to assess personality characteristics, and the Iowa Gambling Task, completed by the participant, was used to assess complex decision-making abilities. Longstanding disturbances in executive personality characteristics were found to be associated with poor decision-making, and these disturbances remained predictive of poor decision-making even after taking into consideration demographic, neuropsychological, and mood factors. Acquired personality disturbances did not add significantly to prediction after longstanding disturbances were taken into account. Disturbances in other dimensions of personality were not significantly associated with poor decision-making. Our study suggests that attentiveness to the personality correlates of difficulties with aspects of executive functioning over the adult years could enhance the ability to identify older individuals at risk for problems with real-world decision-making.

    8. An Inter-Personal Information Sharing Model Based on Personalized Recommendations

      Science.gov (United States)

      Kamei, Koji; Funakoshi, Kaname; Akahani, Jun-Ichi; Satoh, Tetsuji

      In this paper, we propose an inter-personal information sharing model among individuals based on personalized recommendations. In the proposed model, we define an information resource as shared between people when both of them consider it important --- not merely when they both possess it. In other words, the model defines the importance of information resources based on personalized recommendations from identifiable acquaintances. The proposed method is based on a collaborative filtering system that focuses on evaluations from identifiable acquaintances. It utilizes both user evaluations for documents and their contents. In other words, each user profile is represented as a matrix of credibility to the other users' evaluations on each domain of interests. We extended the content-based collaborative filtering method to distinguish other users to whom the documents should be recommended. We also applied a concept-based vector space model to represent the domain of interests instead of the previous method which represented them by a term-based vector space model. We introduce a personalized concept-base compiled from each user's information repository to improve the information retrieval in the user's environment. Furthermore, the concept-spaces change from user to user since they reflect the personalities of the users. Because of different concept-spaces, the similarity between a document and a user's interest varies for each user. As a result, a user receives recommendations from other users who have different view points, achieving inter-personal information sharing based on personalized recommendations. This paper also describes an experimental simulation of our information sharing model. In our laboratory, five participants accumulated a personal repository of e-mails and web pages from which they built their own concept-base. Then we estimated the user profiles according to personalized concept-bases and sets of documents which others evaluated. We simulated

    9. Personality Processes: Mechanisms by which Personality Traits “Get Outside the Skin”

      OpenAIRE

      Hampson, Sarah E.

      2011-01-01

      It is time to better understand why personality traits predict consequential outcomes, which calls for a closer look at personality processes. Personality processes are mechanisms that unfold over time to produce the effects of personality traits. They include reactive and instrumental processes that moderate or mediate the association between traits and outcomes. These mechanisms are illustrated here by a selection of studies of traits representing the three broad domains of personality and ...

    10. Co-occurrence of personality disorders in persons with kleptomania: a preliminary investigation.

      Science.gov (United States)

      Grant, Jon E

      2004-01-01

      This study was conducted to examine the co-occurrence of personality disorders in a group of persons with kleptomania. Twenty-eight subjects with DSM-IV kleptomania were administered the Structured Clinical Interview for DSM-III-R Personality Disorders and a semistructured interview to assess demographics and clinical characteristics. Twelve subjects with kleptomania (42.9%) met criteria for at least one personality disorder. The most common were: paranoid (n = 5; 17.9%), schizoid (n = 3; 10.7%), and borderline (n = 3; 10.7%). Subjects with kleptomania combined with personality disorders had an earlier age of onset of stealing behavior (13.4 +/- 5.6 years compared with 27.4 +/- 14.2 years in those who had kleptomania only; t = 3.225; df = 26; p = .006). Severity of kleptomania symptoms did not differ among the Axis II comorbidities. Persons with kleptomania appear to have a high prevalence of personality disorders. Further studies are needed to understand the relationship of kleptomania to personality.

    11. Suicide and Personality

      Directory of Open Access Journals (Sweden)

      K. Nahit Ozmenler

      2009-07-01

      Full Text Available Many factors may play role in the emergence of suicidal behavior. Familial tendency including some features of personality structure, hopelessness, affective disorder, and suicide behavior have attracted close attention recently. Personality disorders seem to be prevalent in individuals who attempt suicide. Beside it has been reported that personality disorders and other psychiatric disorder comorbidity increase the risk of suicide. To present the relationship between suicide and personality is quite important for developing strategies in order to prevent suicide attempt. In this field, the data show variability based on scales used for the evaluation of personality, its definition and classification in the research. For example, while some authors used DSM criteria or ICD criteria, others preferred to focus on the temperament and character dimensions of personality. In studies based on diagnostic criteria; B group personality disorders, such as antisocial and borderline personality disorders were found to be most common comorbid personality disorder diagnosis. In studies aiming to investigate the relationship among suicide attempt, temperament and character features, the suicide attempters were found to have lower levels of self directedness, cooperativeness, and higher scores for self transcendence. Suicidal patients were inclined to have higher scores in several temperament groups like harm avoidance, novelty seeking, and reward dependence. Tendency to impulsive behavior is reported as a common denominator for suicidal patients. Individuals, who have familial or acquired tendency of impulsivity, could react more dramatically and present with depressive and pessimistic mood when they have difficulties and encounter stress factors in their daily routine and could easily develop depressive disorders. These factors as a whole could lead to self destructive actions like suicide. Individual or familial history of suicide attempts or completed

    12. Personality Disorders

      Science.gov (United States)

      Personality disorders are a group of mental illnesses. They involve long-term patterns of thoughts and behaviors ... serious problems with relationships and work. People with personality disorders have trouble dealing with everyday stresses and ...

    13. Case Study: Let's Get Personal--Putting Personality into Your Cases

      Science.gov (United States)

      Herreid, Clyde Freeman

      2017-01-01

      In this case study, the subject for discussion is the need to use teaching notes in order to add personality to case studies. Personality, it is said, is more important than policy, than demographics, than finances, or amorous peccadillos. Personality is essential. It is the interaction of people that capture our interest, yet, the question is…

    14. Archetype-Based Modeling of Persona for Comprehensive Personality Computing from Personal Big Data

      Science.gov (United States)

      Ma, Jianhua

      2018-01-01

      A model describing the wide variety of human behaviours called personality, is becoming increasingly popular among researchers due to the widespread availability of personal big data generated from the use of prevalent digital devices, e.g., smartphones and wearables. Such an approach can be used to model an individual and even digitally clone a person, e.g., a Cyber-I (cyber individual). This work is aimed at establishing a unique and comprehensive description for an individual to mesh with various personalized services and applications. An extensive research literature on or related to psychological modelling exists, i.e., into automatic personality computing. However, the integrity and accuracy of the results from current automatic personality computing is insufficient for the elaborate modeling in Cyber-I due to an insufficient number of data sources. To reach a comprehensive psychological description of a person, it is critical to bring in heterogeneous data sources that could provide plenty of personal data, i.e., the physiological data, and the Internet data. In addition, instead of calculating personality traits from personal data directly, an approach to a personality model derived from the theories of Carl Gustav Jung is used to measure a human subject’s persona. Therefore, this research is focused on designing an archetype-based modeling of persona covering an individual’s facets in different situations to approach a comprehensive personality model. Using personal big data to measure a specific persona in a certain scenario, our research is designed to ensure the accuracy and integrity of the generated personality model. PMID:29495343

    15. Archetype-Based Modeling of Persona for Comprehensive Personality Computing from Personal Big Data

      Directory of Open Access Journals (Sweden)

      Ao Guo

      2018-02-01

      Full Text Available A model describing the wide variety of human behaviours called personality, is becoming increasingly popular among researchers due to the widespread availability of personal big data generated from the use of prevalent digital devices, e.g., smartphones and wearables. Such an approach can be used to model an individual and even digitally clone a person, e.g., a Cyber-I (cyber individual. This work is aimed at establishing a unique and comprehensive description for an individual to mesh with various personalized services and applications. An extensive research literature on or related to psychological modelling exists, i.e., into automatic personality computing. However, the integrity and accuracy of the results from current automatic personality computing is insufficient for the elaborate modeling in Cyber-I due to an insufficient number of data sources. To reach a comprehensive psychological description of a person, it is critical to bring in heterogeneous data sources that could provide plenty of personal data, i.e., the physiological data, and the Internet data. In addition, instead of calculating personality traits from personal data directly, an approach to a personality model derived from the theories of Carl Gustav Jung is used to measure a human subject’s persona. Therefore, this research is focused on designing an archetype-based modeling of persona covering an individual’s facets in different situations to approach a comprehensive personality model. Using personal big data to measure a specific persona in a certain scenario, our research is designed to ensure the accuracy and integrity of the generated personality model.

    16. Archetype-Based Modeling of Persona for Comprehensive Personality Computing from Personal Big Data.

      Science.gov (United States)

      Guo, Ao; Ma, Jianhua

      2018-02-25

      A model describing the wide variety of human behaviours called personality, is becoming increasingly popular among researchers due to the widespread availability of personal big data generated from the use of prevalent digital devices, e.g., smartphones and wearables. Such an approach can be used to model an individual and even digitally clone a person, e.g., a Cyber-I (cyber individual). This work is aimed at establishing a unique and comprehensive description for an individual to mesh with various personalized services and applications. An extensive research literature on or related to psychological modelling exists, i.e., into automatic personality computing. However, the integrity and accuracy of the results from current automatic personality computing is insufficient for the elaborate modeling in Cyber-I due to an insufficient number of data sources. To reach a comprehensive psychological description of a person, it is critical to bring in heterogeneous data sources that could provide plenty of personal data, i.e., the physiological data, and the Internet data. In addition, instead of calculating personality traits from personal data directly, an approach to a personality model derived from the theories of Carl Gustav Jung is used to measure a human subject's persona. Therefore, this research is focused on designing an archetype-based modeling of persona covering an individual's facets in different situations to approach a comprehensive personality model. Using personal big data to measure a specific persona in a certain scenario, our research is designed to ensure the accuracy and integrity of the generated personality model.

    17. Personality Disorders

      Science.gov (United States)

      ... Disorders in Adults Data Sources Share Personality Disorders Definitions Personality disorders represent “an enduring pattern of inner ... MSC 9663 Bethesda, MD 20892-9663 Follow Us Facebook Twitter YouTube Google Plus NIMH Newsletter NIMH RSS ...

    18. Mechanisms shaping the development of personality and personality disorders in children and adolescents.

      Science.gov (United States)

      Lenkiewicz, Kamila; Srebnicki, Tomasz; Bryńska, Anita

      2016-01-01

      Until the end of the nineties last century personality disorders could not be diagnosed before the age of eighteen. Nevertheless, the results of studies published in the last decade have revealed that personality disorders can be observed in children and adolescents and that personality disorders diagnosed in adult patients had been present as early as in childhood. The knowledge of possible mechanisms shaping personality disorders in childhood is unsatisfactory and needs to be expanded. Developmental psychology explains the development of abnormal personality through inappropriate attachment patterns and abnormal transitions between developmental phases. Genetic and temperamental factors are also important in the aetiology of personality disorders as well as early maladaptive schemas resulting from personal experiences and interactions with others. The aim of this article is to review the current knowledge on the mechanisms shaping the development of personality and personality disorders in childhood and adolescence.

    19. Semi-empirical model for the calculation of flow friction factors in wire-wrapped rod bundles

      International Nuclear Information System (INIS)

      Carajilescov, P.; Fernandez y Fernandez, E.

      1981-08-01

      LMFBR fuel elements consist of wire-wrapped rod bundles, with triangular array, with the fluid flowing parallel to the rods. A semi-empirical model is developed in order to obtain the average bundle friction factor, as well as the friction factor for each subchannel. The model also calculates the flow distribution factors. The results are compared to experimental data for geometrical parameters in the range: P(div)D = 1.063 - 1.417, H(div)D = 4 - 50, and are considered satisfactory. (Author) [pt

    20. Exploring the Role of In-Person Components for Online Health Behavior Change Interventions: Can a Digital Person-to-Person Component Suffice?

      Science.gov (United States)

      Santarossa, Sara; Kane, Deborah; Senn, Charlene Y; Woodruff, Sarah J

      2018-04-11

      The growth of the digital environment provides tremendous opportunities to revolutionize health behavior change efforts. This paper explores the use of Web-based, mobile, and social media health behavior change interventions and determines whether there is a need for a face-to-face or an in-person component. It is further argued that that although in-person components can be beneficial for online interventions, a digital person-to-person component can foster similar results while dealing with challenges faced by traditional intervention approaches. Using a digital person-to-person component is rooted in social and behavioral theories such as the theory of reasoned action, and the social cognitive theory, and further justified by the human support constructs of the model of supportive accountability. Overall, face-to-face and online behavior change interventions have their respective advantages and disadvantages and functions, yet both serve important roles. It appears that it is in fact human support that is the most important component in the effectiveness and adherence of both face-to-face and online behavior change interventions, and thoughtfully introducing a digital person-to-person component, to replace face-to-face interactions, can provide the needed human support while diminishing the barriers of in-person meetings. The digital person-to-person component must create accountability, generate opportunities for tailored feedback, and create social support to successfully create health behavior change. As the popularity of the online world grows, and the interest in using the digital environment for health behavior change interventions continues to be embraced, further research into not only the use of online interventions, but the use of a digital person-to-person component, must be explored. ©Sara Santarossa, Deborah Kane, Charlene Y Senn, Sarah J Woodruff. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 11.04.2018.

    1. BACTERIOLOGICAL CHARACTERISTICS OF WASHED AND UNWASHED LAYING HEN’S EGGS CARACTERÍSTICAS BACTERIOLÓGICAS DE OVOS LAVADOS E NÃO LAVADOS DE GRANJAS DE PRODUÇÃO COMERCIAL

      Directory of Open Access Journals (Sweden)

      Maria Luiza Ferreira Stringhini

      2009-12-01

      causing human intoxication. Although low frequency (2.1%, it was verified the presence of faecal coliforms in number greater than 100 germs/g of eggshell in the classification hall of the farms that washed mechanically the eggs. It was not observe the presence of Salmonella spp. in all the eggshells collected neither contamination in contents of the eggs. It was concluded that washed eggs from commercial egg farms had better eggshell bacteriological quality than unwashed eggs but the washing process adopted was not able to completely eliminate the fecal coliforms.<div>
      div>>KEY WORDS: Commercial eggs, egg washing, food safety, microbiological contamination.div>>
      div> <div>A avaliação da qualidade bacteriológica de ovos lavados e não lavados de quatro granjas de postura comercial da região metropolitana de Goiânia, GO, constituiu o objetivo do presente estudo. As Granjas 1 e 2 eram de médio e pequeno porte, respectivamente, e realizavam a lavagem mecanizada dos ovos com água aquecida contendo sanitizante; as Granjas 3 e 4 comercializavam ovos não lavados. O universo amostral foi constituído por 576 ovos das Granjas 1 e 2, e 132 ovos obtidos nas Granjas 3 e 4, sendo metade coletada nos galpões e a outra metade na sala de classificação. Avaliaram-se ovos classificados como grandes, de poedeiras leves, com trinta a quarenta semanas de idade, da linhagem Dekalb White. O delineamento utilizado foi inteiramente casualizado em esquema fatorial 2 x 2 (procedimento de lavagem x local da coleta, com três repetições, e a unidade experimental consistiu de pool de seis ovos. Efetuaram-se contagens de mesófilos e Staphylococcus coagulase positivo e número mais provável (NMP de coliformes totais e fecais nas cascas e conteúdos dos ovos e pesquisa de Salmonella spp. nas cascas. Resultados das contagens foram expressos em log UFC/g e aplicou-se o teste “t” de Student (5%. Análises descritiva e de frequência foram adotadas para NMP de

    2. 77 FR 12235 - Wooden Bedroom Furniture From the People's Republic of China: Initiation of Administrative Review

      Science.gov (United States)

      2012-02-29

      .... Kent Hospitality, Inc. Champion Sun Industries Limited Changshu HTC Import & Export Co., Ltd.* Cheng... Industry Co. Ltd.* Shanghai Hospitality Product Mfg., Co., Ltd. Shanghai Industries Group Shanghai Jian Pu... Co., Ltd.;* Artwork Metal & Plastic Co., Ltd.;* Jibson Industries Ltd.;* Always Loyal International...

    3. 76 FR 10880 - Initiation of Administrative Review of the Antidumping Duty Order on Wooden Bedroom Furniture...

      Science.gov (United States)

      2011-02-28

      .... C.F. Kent Hospitality, Inc. Champion Sun Industries Limited. Changshu HTC Import & Export Co., Ltd... Hospitality Product Mfg., Co., Ltd. Shanghai Industries Group. Shanghai Jian Pu Export & Import Co., Ltd...., Ltd.;* Artwork Metal & Plastic Co., Ltd.;* Jibson Industries Ltd.,* Always Loyal International* Baigou...

    4. Induction of feline immunodeficiency virus specific antibodies in cats with an attenuated Salmonella strain expressing the Gag protein.

      NARCIS (Netherlands)

      E.J. Tijhaar (Edwin); C.H.J. Siebelink (Kees); J.A. Karlas (Jos); M.C. Burger; F.R. Mooi (Frits); A.D.M.E. Osterhaus (Albert)

      1997-01-01

      textabstractSalmonella typhimurium aroA strains (SL3261), expressing high levels of the Gag protein of feline immunodeficiency virus (FIV) fused with maltose binding protein (SL3261-MFG), were constructed using an invertible promoter system that allows the stable expression of heterologous antigens

    5. Measuring personality : a comparison of three personality questionnaires in the Netherlands

      NARCIS (Netherlands)

      Barelds, D.P.H.; Luteijn, F.

      Three studies were conducted in order to examine (1) what can be measured with three commonly used Dutch self-report personality questionnaires, and (2) which instrument is most suitable for measuring personality in The Netherlands. In Study 1, the relationships between the Five Factor Personality

    6. Personality Predicts Cognitive Function Over Seven Years in Older Persons

      Science.gov (United States)

      Chapman, Benjamin; Duberstein, Paul; Tindle, Hilary A; Sink, Kaycee M; Robbins, John; Tancredi, Daniel J.; Franks, Peter

      2011-01-01

      Objectives To determine whether Neuroticism, as well as the less-studied dimensions the Five Factor Model of personality (Extraversion, Openness to Experience, Agreeableness, and Conscientiousness) were associated with 7-year trajectories of cognitive functioning in older persons. Design Primary analysis of existing clinical trial data. Participants 602 persons of average age 79 at baseline. Measurements The NEO-Five Factor Inventory of personality, completed at baseline, and the modified Mini Mental Status Exam (3MSE) measured every 6 months for 7 years. Results Controlling for demographics, baseline morbidities including depression, health behaviors, Apolipoprotein E4 genotype, and self-rated health, higher Neuroticism was associated with worse average cognitive functioning and a steeper rate of decline over follow-up. Higher Extraversion and lower Openness were both associated with worse average cognitive functioning prospectively, while persons higher in Conscientiousness showed a slower rate of cognitive decline. Conclusions In addition to Neuroticism, other dispositional tendencies appear prognostically relevant for cognitive functioning in older persons. More work is needed to understand the mechanisms by which traits operate, as well as whether mitigation of certain dispositional tendencies can facilitate a better course of cognitive function. PMID:22735597

    7. Personal Hygiene Practices among Urban Homeless Persons in Boston, MA

      OpenAIRE

      Leibler, Jessica H.; Nguyen, Daniel D.; Le?n, Casey; Gaeta, Jessie M.; Perez, Debora

      2017-01-01

      Persons experiencing homelessness in the United States experience significant barriers to self-care and personal hygiene, including limited access to clean showers, laundry and hand washing facilities. While the obstacles to personal hygiene associated with homelessness may increase risk of infectious disease, hygiene-related behaviors among people experiencing homelessness has received limited attention. We conducted a cross-sectional study of individuals experiencing homelessness in Boston,...

    8. Destination Personality: An Application of Brand Personality to Tourism Destinations

      OpenAIRE

      Ekinci, Yuksel; Hosany, Sameer

      2006-01-01

      In an increasingly competitive tourism market place, destination marketers face the challenge of attracting tourists through destination branding and destination personality building practices. As places become substitutable, destination personality, defined as the set of human characteristics associated with a destination, is seen as a viable metaphor for crafting a destination’s unique identity. At the conceptual level, the importance of destination personality has been widely acknowledged,...

    9. The five-factor model of personality and borderline personality disorder: a genetic analysis of comorbidity.

      Science.gov (United States)

      Distel, Marijn A; Trull, Timothy J; Willemsen, Gonneke; Vink, Jacqueline M; Derom, Catherine A; Lynskey, Michael; Martin, Nicholas G; Boomsma, Dorret I

      2009-12-15

      Recently, the nature of personality disorders and their relationship with normal personality traits has received extensive attention. The five-factor model (FFM) of personality, consisting of the personality traits neuroticism, extraversion, openness to experience, agreeableness, and conscientiousness, is one of the proposed models to conceptualize personality disorders as maladaptive variants of continuously distributed personality traits. The present study examined the phenotypic and genetic association between borderline personality and FFM personality traits. Data were available for 4403 monozygotic twins, 4425 dizygotic twins, and 1661 siblings from 6140 Dutch, Belgian, and Australian families. Broad-sense heritability estimates for neuroticism, agreeableness, conscientiousness, extraversion, openness to experience, and borderline personality were 43%, 36%, 43%, 47%, 54%, and 45%, respectively. Phenotypic correlations between borderline personality and the FFM personality traits ranged from .06 for openness to experience to .68 for neuroticism. Multiple regression analyses showed that a combination of high neuroticism and low agreeableness best predicted borderline personality. Multivariate genetic analyses showed the genetic factors that influence individual differences in neuroticism, agreeableness, conscientiousness, and extraversion account for all genetic liability to borderline personality. Unique environmental effects on borderline personality, however, were not completely shared with those for the FFM traits (33% is unique to borderline personality). Borderline personality shares all genetic variation with neuroticism, agreeableness, conscientiousness, and extraversion. The unique environmental influences specific to borderline personality may cause individuals with a specific pattern of personality traits to cross a threshold and develop borderline personality.

    10. The Schedule for Nonadaptive and Adaptive Personality for Youth (SNAP-Y): A New Measure for Assessing Adolescent Personality and Personality Pathology

      Science.gov (United States)

      Linde, Jennifer A.; Stringer, Deborah; Simms, Leonard J.; Clark, Lee Anna

      2013-01-01

      The Schedule for Nonadaptive and Adaptive Personality-Youth Version (SNAP-Y) is a new, reliable self-report questionnaire that assesses 15 personality traits relevant to both normal-range personality and the alternative "DSM"-5 model for personality disorder. Community adolescents, 12 to 18 years old (N = 364), completed the SNAP-Y; 347…

    11. Personality Development at Work: Workplace Conditions, Personality Changes, and the Corresponsive Principle

      Science.gov (United States)

      Le, Kimdy; Donnellan, M. Brent; Conger, Rand

      2013-01-01

      Objective Investigations concerning adult personality development have increasingly focused on factors that are associated with apparent personality trait changes. The current study contributes to this literature by replicating and extending previous research concerning personality trait development in young adulthood and perceptions of workplace conditions. Method Analyses were based on up to 442 individuals who participated in the ongoing Family Transitions Project (e.g., Conger & Conger, 2002). The current analyses included personality trait data from 1994 and 2003, high-school grades and SES indicators from 1994, and reports about work conditions in 2001, 2003, and 2005. Results Personality attributes were prospectively associated with work conditions and income. Findings also support the corresponsive principle of personality development (e.g. Roberts, Caspi, & Moffitt, 2003): Traits that were prospectively associated with particular workplace conditions often seemed to be accentuated by those conditions. Conclusions Personality traits are prospectively associated with perceptions of the workplace. Workplace conditions are also associated with trait development. PMID:23336723

    12. Personality Development at Work: Workplace Conditions, Personality Changes, and the Corresponsive Principle.

      Science.gov (United States)

      Le, Kimdy; Donnellan, M Brent; Conger, Rand

      2014-02-01

      Investigations concerning adult personality development have increasingly focused on factors that are associated with apparent personality trait changes. The current study contributes to this literature by replicating and extending previous research concerning personality trait development in young adulthood and perceptions of workplace conditions. Analyses were based on up to 442 individuals who participated in the ongoing Family Transitions Project (e.g., Conger & Conger, 2002). The current analyses included personality trait data from 1994 and 2003, high school grades and socioeconomic status indicators from 1994, and reports about work conditions in 2001, 2003, and 2005. Personality attributes were prospectively associated with work conditions and income. Findings also support the corresponsive principle of personality development (e.g., Roberts, Caspi, & Moffitt, 2003): Traits that were prospectively associated with particular workplace conditions often seemed to be accentuated by those conditions. Personality traits are prospectively associated with perceptions of the workplace. Workplace conditions are also associated with trait development. © 2013 Wiley Periodicals, Inc.

    13. Personal factors and personality characteristics as predictors of ...

      African Journals Online (AJOL)

      The study set to investigate personal factors and personality characteristics as Predictors of customers satisfaction with health care services. The study utilized Ex-Post Facto design. A total number of 100 participants took part in the study which were made up of 57 (57%) males and 48 (48%) females, with a mean age of ...

    14. Ideology, affect, semiotics: towards a non-personal theory of personality.

      Science.gov (United States)

      Larocco, Steve

      2014-06-01

      Personality theories, as Giordano (2014) argues, often treat Western versions of the self as having universal import. Eastern notions of self, however, offer a dramatically different basis for thinking about what personality might be. This paper, nonetheless, seeks to offer a general framework for theorizing about the epiphenomenon of personality in any culture, asserting that it is an effect of specific histories of ideological practices, semiotic networks and systems, and affect, which engage each other in dialogic and dialectical ways. The interactions of these factors, guided by ideology, regularize behavior and affective dynamics, largely in non-personal ways. Subjects are produced and reproduced from these complex interactions, which are situationally specific and simultaneously transpersonal. The subjects formed through these interactions are the basis for the folk psychology of personality, which treats the transient, varying effects of these interactions as more or less reified qualities that form a basis for the construction of selfhood, however conceived.

    15. Activity groups for persons with dementia: Personal predictors of participation, engagement and mood.

      Science.gov (United States)

      Cohen-Mansfield, Jiska

      2017-11-01

      This study examined the relationship between personal characteristics and attendance, engagement, sleep, and mood outcomes of persons with dementia participating in group activities. The purpose of this study is to examine which persons with dementia benefit most from group interventions. Sixty-nine persons with dementia were observed by research and therapeutic recreation staff during 10 types of group activities (reading aloud with discussion, choral-singing, baking, creative storytelling, brain games, active games, exercise, reminiscence poetry, holiday newsletter, and holiday discussions) on multiple outcomes (attendance duration, sleep, engagement, active participation, attitude, and positive mood). Correlations between these outcomes and personal characteristics (demographics, functional and medical characteristics, personal preferences for group activities) were conducted. Variables with significant correlations were then entered into regression analyses. Many of the personal characteristics were significantly correlated with the outcomes. Cognitive function was the most consistent predictor of all outcomes. Personal characteristics, particularly cognitive function, can predict the responses of persons with dementia during group activities. Copyright © 2017 Elsevier B.V. All rights reserved.

    16. The contribution of additive genetic variation to personality variation: heritability of personality.

      Science.gov (United States)

      Dochtermann, Ned A; Schwab, Tori; Sih, Andrew

      2015-01-07

      Individual animals frequently exhibit repeatable differences from other members of their population, differences now commonly referred to as 'animal personality'. Personality differences can arise, for example, from differences in permanent environmental effects--including parental and epigenetic contributors--and the effect of additive genetic variation. Although several studies have evaluated the heritability of behaviour, less is known about general patterns of heritability and additive genetic variation in animal personality. As overall variation in behaviour includes both the among-individual differences that reflect different personalities and temporary environmental effects, it is possible for personality to be largely genetically influenced even when heritability of behaviour per se is quite low. The relative contribution of additive genetic variation to personality variation can be estimated whenever both repeatability and heritability are estimated for the same data. Using published estimates to address this issue, we found that approximately 52% of animal personality variation was attributable to additive genetic variation. Thus, while the heritability of behaviour is often moderate or low, the heritability of personality is much higher. Our results therefore (i) demonstrate that genetic differences are likely to be a major contributor to variation in animal personality and (ii) support the phenotypic gambit: that evolutionary inferences drawn from repeatability estimates may often be justified. © 2014 The Author(s) Published by the Royal Society. All rights reserved.

    17. The Sport Expert's Attention Superiority on Skill-related Scene Dynamic by the Activation of left Medial Frontal Gyrus: An ERP and LORETA Study.

      Science.gov (United States)

      He, Mengyang; Qi, Changzhu; Lu, Yang; Song, Amanda; Hayat, Saba Z; Xu, Xia

      2018-05-21

      Extensive studies have shown that a sports expert is superior to a sports novice in visually perceptual-cognitive processes of sports scene information, however the attentional and neural basis of it has not been thoroughly explored. The present study examined whether a sport expert has the attentional superiority on scene information relevant to his/her sport skill, and explored what factor drives this superiority. To address this problem, EEGs were recorded as participants passively viewed sport scenes (tennis vs. non-tennis) and negative emotional faces in the context of a visual attention task, where the pictures of sport scenes or of negative emotional faces randomly followed the pictures with overlapping sport scenes and negative emotional faces. ERP results showed that for experts, the evoked potential of attentional competition elicited by the overlap of tennis scene was significantly larger than that evoked by the overlap of non-tennis scene, while this effect was absent for novices. The LORETA showed that the experts' left medial frontal gyrus (MFG) cortex was significantly more active as compared to the right MFG when processing the overlap of tennis scene, but the lateralization effect was not significant in novices. Those results indicate that experts have attentional superiority on skill-related scene information, despite intruding the scene through negative emotional faces that are prone to cause negativity bias toward their visual field as a strong distractor. This superiority is actuated by the activation of left MFG cortex and probably due to self-reference. Copyright © 2018 The Authors. Published by Elsevier Ltd.. All rights reserved.

    18. Personality Patterns of Physicians in Person-Oriented and Technique-Oriented Specialties

      Science.gov (United States)

      Borges, Nicole J.; Gibson, Denise D.

      2005-01-01

      This study investigated differences in personality patterns between person-oriented and technique-oriented physicians. It tested an integrative framework by converting the scores on the Personality Research Form (PRF) to the Big-Five factors and built a predictive model of group membership in clinical specialty area. PRF scores from 238 physicians…

    19. A parallel process growth model of avoidant personality disorder symptoms and personality traits.

      Science.gov (United States)

      Wright, Aidan G C; Pincus, Aaron L; Lenzenweger, Mark F

      2013-07-01

      Avoidant personality disorder (AVPD), like other personality disorders, has historically been construed as a highly stable disorder. However, results from a number of longitudinal studies have found that the symptoms of AVPD demonstrate marked change over time. Little is known about which other psychological systems are related to this change. Although cross-sectional research suggests a strong relationship between AVPD and personality traits, no work has examined the relationship of their change trajectories. The current study sought to establish the longitudinal relationship between AVPD and basic personality traits using parallel process growth curve modeling. Parallel process growth curve modeling was applied to the trajectories of AVPD and basic personality traits from the Longitudinal Study of Personality Disorders (Lenzenweger, M. F., 2006, The longitudinal study of personality disorders: History, design considerations, and initial findings. Journal of Personality Disorders, 20, 645-670. doi:10.1521/pedi.2006.20.6.645), a naturalistic, prospective, multiwave, longitudinal study of personality disorder, temperament, and normal personality. The focus of these analyses is on the relationship between the rates of change in both AVPD symptoms and basic personality traits. AVPD symptom trajectories demonstrated significant negative relationships with the trajectories of interpersonal dominance and affiliation, and a significant positive relationship to rates of change in neuroticism. These results provide some of the first compelling evidence that trajectories of change in PD symptoms and personality traits are linked. These results have important implications for the ways in which temporal stability is conceptualized in AVPD specifically, and PD in general.

    20. Relating DSM-5 section III personality traits to section II personality disorder diagnoses.

      Science.gov (United States)

      Morey, L C; Benson, K T; Skodol, A E

      2016-02-01

      The DSM-5 Personality and Personality Disorders Work Group formulated a hybrid dimensional/categorical model that represented personality disorders as combinations of core impairments in personality functioning with specific configurations of problematic personality traits. Specific clusters of traits were selected to serve as indicators for six DSM categorical diagnoses to be retained in this system - antisocial, avoidant, borderline, narcissistic, obsessive-compulsive and schizotypal personality disorders. The goal of the current study was to describe the empirical relationships between the DSM-5 section III pathological traits and DSM-IV/DSM-5 section II personality disorder diagnoses. Data were obtained from a sample of 337 clinicians, each of whom rated one of his or her patients on all aspects of the DSM-IV and DSM-5 proposed alternative model. Regression models were constructed to examine trait-disorder relationships, and the incremental validity of core personality dysfunctions (i.e. criterion A features for each disorder) was examined in combination with the specified trait clusters. Findings suggested that the trait assignments specified by the Work Group tended to be substantially associated with corresponding DSM-IV concepts, and the criterion A features provided additional diagnostic information in all but one instance. Although the DSM-5 section III alternative model provided a substantially different taxonomic structure for personality disorders, the associations between this new approach and the traditional personality disorder concepts in DSM-5 section II make it possible to render traditional personality disorder concepts using alternative model traits in combination with core impairments in personality functioning.

    1. Violence and Personality in Forensic Patients: Is There a Forensic Patient-Specific Personality Profile?

      Science.gov (United States)

      Stupperich, Alexandra; Ihm, Helga; Strack, Micha

      2009-01-01

      Concerning the discussion about the connection of personality traits, personality disorders, and mental illness, this study focused on the personality profiles of male forensic patients, prison inmates, and young men without criminal reports. The main topic centered on group-specific personality profiles and identifying personality facets…

    2. Investigating the prevalence of personality disorders and its relationship with personality traits among students

      Directory of Open Access Journals (Sweden)

      Davod Ghaderi

      2016-04-01

      Full Text Available The present study was aimed to investigate the prevalence of personality disorders and its relationship with personality traits among students. This research was among epidemiological-correlational descriptive studies. Method: For this purpose, 389 male students were selected via a multi-stage cluster sampling method. All subjects completed Millon's personality disorder (1987 and five-factor personality Costaand McCrae's questionnaires (1989. Results: The results showed that the prevalence of personality disorders is among students. It was also found that there existed a positive correlation between schizoid, avoidant, dependent, schizotypal, borderline and paranoid personality disorders with Neuroticism factor (r = .1. There was a significant negative correlation between schizoid, avoidant and schizotypal personality disorders with extraversion factor (r = .1 and significant positive correlation between histrionic disorders and extraversion (r = .1. There was a significant negative correlation between dependent personality disorder and Openness factor (r = .1 , significant negative correlation between narcissistic, antisocial and paranoid personality disorders with agree ableness factor (r = .1 and finally, significant negative correlation between antisocial, passive-aggressive and borderline personality disorders with accountability factor (r = .1and a significant positive correlation between accountability factor and compulsive personality disorder (r = .1. Conclusion: The results suggest a prevalence of personality disorders among students and significant correlation between some disorders with personality factors. Further studies in this area could provide more insightful findings in the field.

    3. Predicting personality disorder functioning styles by the Chinese Adjective Descriptors of Personality: a preliminary trial in healthy people and personality disorder patients.

      Science.gov (United States)

      Fan, Hongying; Zhu, Qisha; Ma, Guorong; Shen, Chanchan; Zhang, Bingren; Wang, Wei

      2016-08-30

      Cultural and personality factors might contribute to the clinical differences of psychiatric patients all over the world including China. One cultural oriented Chinese Adjective Descriptors of Personality (CADP) designed to measure normal personality traits, might be specifically associated with different personality disorder functioning styles. We therefore have invited 201 healthy volunteers and 67 personality disorder patients to undergo CADP, the Parker Personality Measure (PERM), and the Plutchik-van Praag Depression Inventory (PVP) tests. Patients scored significantly higher on PVP scale and all 11 PERM personality disorder functioning styles, as well as CADP Emotional and Unsocial traits. The PVP was significantly correlated with some CADP traits and PERM styles in both groups. In healthy volunteers, only one CADP trait, Unsocial, prominently predicted 11 PERM styles. By contrast in patients, CADP Intelligent predicted the PERM Narcissistic and Passive-Aggressive styles; CADP Emotional the PERM Paranoid, Borderline, and Histrionic styles; CADP Conscientious the PERM Obsessive-Compulsive style; CADP Unsocial the PERM Schizotypal, Antisocial, Narcissistic, Avoidant, Dependent, and Passive-Aggressive styles; CADP Agreeable the PERM Antisocial style. As a preliminary study, our results demonstrated that, in personality disorder patients, all five CADP traits were specifically associated with almost all 11 personality disorder functioning styles, indicating that CADP might be used as an aid to diagnose personality disorders in China.

    4. The Fall of Crete 1941: Was Freyberg Culpable?

      Science.gov (United States)

      2006-06-16

      where he served out the war in this capacity and then as the Viceroy of India. Ian Beckett’s chapter contained in John Keegan’s book Churchill’s...Div formed part of an expeditionary force (“W Force”) under General Sir Harry Maitland Wilson,15 along with Blamey’s 6th and 7th Aust Divs, a Polish...Marshal) Sir Henry Maitland Wilson (1881–1964) served in both the Boer War and World War 1. He commanded British forces in Egypt prior to the Greek

    5. Operation Statistics of the CERN Accelerators Complex for 2003

      CERN Document Server

      CERN. Geneva; Baird, S A; Rey, A; Steerenberg, R; CERN. Geneva. AB Department

      2004-01-01

      This report gives an overview of the performance of the different Accelerators (Linacs, PS Booster, PS, AD and SPS) of the CERN Accelerator Complex for 2003. It includes scheduled activities, beam availabilities, beam intensities and an analysis of faults and breakdowns by system and by beam. MORE INFORATION by using the OP Statistics Tool: http://eLogbook.web.cern.ch/eLogbook/statistics.php and on the SPS HomePage: http://ab-div-op-sps.web.cern.ch/ab-div-op-sps/SPSss.html

    6. 76 FR 1067 - Testing of Certain High Production Volume Chemicals; Second Group of Chemicals

      Science.gov (United States)

      2011-01-07

      ... Mfg & NOES (number based criteria based criteria significant chemicals (lbs) industrial of workers... 2070-AD16 Testing of Certain High Production Volume Chemicals; Second Group of Chemicals AGENCY... section 4(a)(1)(B) of the Toxic Substances Control Act (TSCA) to require manufacturers, importers, and...

    7. Multiple Family Groups for Child Behavior Difficulties: Retention Among Child Welfare-Involved Caregivers

      Science.gov (United States)

      Gopalan, Geetha; Fuss, Ashley; Wisdom, Jennifer P.

      2015-01-01

      Purpose: The Multiple Family Group (MFG) service delivery model to reduce childhood disruptive behavior disorders has shown promise in engaging child welfare-involved families. This qualitative study examines caregivers' perceptions of factors that influence retention in MFGs among child welfare-involved families. Methods: Twenty-five…

    8. First-person and third-person verbs in visual motion-perception regions.

      Science.gov (United States)

      Papeo, Liuba; Lingnau, Angelika

      2015-02-01

      Verb-related activity is consistently found in the left posterior lateral cortex (PLTC), encompassing also regions that respond to visual-motion perception. Besides motion, those regions appear sensitive to distinctions among the entities beyond motion, including that between first- vs. third-person ("third-person bias"). In two experiments, using functional magnetic resonance imaging (fMRI), we studied whether the implied subject (first/third-person) and/or the semantic content (motor/non-motor) of verbs modulate the neural activity in the left PLTC-regions responsive during basic- and biological-motion perception. In those sites, we found higher activity for verbs than for nouns. This activity was modulated by the person (but not the semantic content) of the verbs, with stronger response to third- than first-person verbs. The third-person bias elicited by verbs supports a role of motion-processing regions in encoding information about the entity beyond (and independently from) motion, and sets in a new light the role of these regions in verb processing. Copyright © 2014 Elsevier Inc. All rights reserved.

    9. Estimating Between-Person and Within-Person Subscore Reliability with Profile Analysis.

      Science.gov (United States)

      Bulut, Okan; Davison, Mark L; Rodriguez, Michael C

      2017-01-01

      Subscores are of increasing interest in educational and psychological testing due to their diagnostic function for evaluating examinees' strengths and weaknesses within particular domains of knowledge. Previous studies about the utility of subscores have mostly focused on the overall reliability of individual subscores and ignored the fact that subscores should be distinct and have added value over the total score. This study introduces a profile reliability approach that partitions the overall subscore reliability into within-person and between-person subscore reliability. The estimation of between-person reliability and within-person reliability coefficients is demonstrated using subscores from number-correct scoring, unidimensional and multidimensional item response theory scoring, and augmented scoring approaches via a simulation study and a real data study. The effects of various testing conditions, such as subtest length, correlations among subscores, and the number of subtests, are examined. Results indicate that there is a substantial trade-off between within-person and between-person reliability of subscores. Profile reliability coefficients can be useful in determining the extent to which subscores provide distinct and reliable information under various testing conditions.

    10. Person-city personality fit and entrepreneurial success: An explorative study in China.

      Science.gov (United States)

      Zhou, Mingjie; Zhou, Yixin; Zhang, Jianxin; Obschonka, Martin; Silbereisen, Rainer K

      2017-08-13

      While the study of personality differences is a traditional psychological approach in entrepreneurship research, economic research directs attention towards the entrepreneurial ecosystems in which entrepreneurial activity are embedded. We combine both approaches and quantify the interplay between the individual personality make-up of entrepreneurs and the local personality composition of ecosystems, with a special focus on person-city personality fit. Specifically, we analyse personality data from N = 26,405 Chinese residents across 42 major Chinese cities, including N = 1091 Chinese entrepreneurs. Multi-level polynomial regression and response surface plots revealed that: (a) individual-level conscientiousness had a positive effect and individual-level agreeableness and neuroticism had a negative effect on entrepreneurial success, (b) city-level conscientiousness had a positive, and city-level neuroticism had a negative effect on entrepreneurial success, and (c) additional person-city personality fit effects existed for agreeableness, conscientiousness and neuroticism. For example, entrepreneurs who are high in agreeableness and conduct their business in a city with a low agreeableness level show the lowest entrepreneurial success. In contrast, entrepreneurs who are low in agreeableness and conduct their business in a city with a high agreeableness level show relatively high entrepreneurial success. Implications for research and practice are discussed. © 2017 International Union of Psychological Science.

    11. A dimensional approach to assessing personality functioning: examining personality trait domains utilizing DSM-IV personality disorder criteria.

      Science.gov (United States)

      Christopher Fowler, J; Sharp, Carla; Kalpakci, Allison; Madan, Alok; Clapp, Joshua; Allen, Jon G; Christopher Frueh, B; Oldham, John M

      2015-01-01

      This study compared a dimensional, trait domain approach to characterizing personality pathology with the traditional polythetic approach with respect to their associations with interpersonal functioning and personality traits from the five factor model. Psychiatric inpatients (N=1476) were administered the Structured Clinical Interview for DSM-IV Axis II personality disorders. Dimensional representations of trait domains were derived from reorganizing DSM-IV criteria into personality trait domains from DSM-5 Alternative Model. Dimensional scores and personality disorder (PD) total criterion scores served as independent variables in predicting interpersonal profile clusters, as well as extraversion, agreeableness conscientiousness, neuroticism and openness from the five factor model traits. Trait domain scores and PD criteria totals were significantly correlated with submissive interpersonal style yet none proved significant in regression analyses. Avoidant and borderline PD total criteria were negatively associated with a normative interpersonal style. Combined trait domain of detachment and avoidant PD total criteria predicted a hostile/withdrawn interpersonal style. The trait domain of detachment was negatively associated with five factor traits of extroversion, whereas borderline PD total criteria were negatively associated with conscientiousness. Avoidant and borderline PD total criteria were positively associated with neuroticism. The cross-cutting dimensional approach provided useful information in predicting a hostile/withdrawn interpersonal style as well as extroversion. Importantly, PD criterion scores and dimensional trait scores combined to predict this interpersonal style providing support to the alternative model of personality diagnosis in DSM-5. Clinicians are encouraged to assess dimensions of personality traits as these are related to interpersonal problems frequently encountered in psychiatric settings. While potentially useful, the dimensional

    12. Managing Your Personal Brand

      Science.gov (United States)

      Gander, Michelle

      2014-01-01

      Everyone has a personal brand. To ensure success at work you need to manage your personal brand which is made up of your tangible and intangible attributes. This paper reviews the literature around personal branding, looks at some of the attributes and discusses ways you can reflect and begin to build your personal brand in a higher education…

    13. A Parallel Process Growth Model of Avoidant Personality Disorder Symptoms and Personality Traits

      Science.gov (United States)

      Wright, Aidan G. C.; Pincus, Aaron L.; Lenzenweger, Mark F.

      2012-01-01

      Background Avoidant personality disorder (AVPD), like other personality disorders, has historically been construed as a highly stable disorder. However, results from a number of longitudinal studies have found that the symptoms of AVPD demonstrate marked change over time. Little is known about which other psychological systems are related to this change. Although cross-sectional research suggests a strong relationship between AVPD and personality traits, no work has examined the relationship of their change trajectories. The current study sought to establish the longitudinal relationship between AVPD and basic personality traits using parallel process growth curve modeling. Methods Parallel process growth curve modeling was applied to the trajectories of AVPD and basic personality traits from the Longitudinal Study of Personality Disorders (Lenzenweger, 2006), a naturalistic, prospective, multiwave, longitudinal study of personality disorder, temperament, and normal personality. The focus of these analyses is on the relationship between the rates of change in both AVPD symptoms and basic personality traits. Results AVPD symptom trajectories demonstrated significant negative relationships with the trajectories of interpersonal dominance and affiliation, and a significant positive relationship to rates of change in neuroticism. Conclusions These results provide some of the first compelling evidence that trajectories of change in PD symptoms and personality traits are linked. These results have important implications for the ways in which temporal stability is conceptualized in AVPD specifically, and PD in general. PMID:22506627

    14. Complementary approaches to the assessment of personality disorder. The Personality Assessment Schedule and Adult Personality Functioning Assessment compared.

      Science.gov (United States)

      Hill, J; Fudge, H; Harrington, R; Pickles, A; Rutter, M

      2000-05-01

      Current concepts and measures of personality disorder are in many respects unsatisfactory. To establish agreement between two contrasting measures of personality disorder, and to compare subject-informant agreement on each. To examine the extent to which trait abnormality can be separated from interpersonal and social role dysfunction. Fifty-six subjects and their closest informants were interviewed and rated independently. Personality functioning was assessed using a modified Personality Assessment Schedule (M-PAS), and the Adult Personality Functioning Assessment (APFA). Subject-informant agreement on the M-PAS was moderately good, and agreement between the M-PAS and the APFA, across and within subjects and informants, was comparable to that for the M-PAS. This was equally the case when M-PAS trait plus impairment scores and trait abnormality scores were used. The M-PAS and the APFA are probably assessing similar constructs. Trait abnormalities occur predominantly in an interpersonal context and could be assessed within that context.

    15. Personal anticipated information need

      Directory of Open Access Journals (Sweden)

      H. Bruce

      2005-01-01

      Full Text Available Background. The role of personal information collections is a well known feature of personal information management. The World Wide Web has introduced to such collections ideas such as filing Web pages or noting their existence in 'Bookmarks' and 'Favourites'. Argument. It is suggested that personal information collections are created in anticipation of some future need for that information-personal, anticipated information need, which also underlies the design of formal information systems. Elaboration. Examination of the literature of information needs and information seeking behaviour leads to the formulation of five propositions that elaborate the concept of personal, anticipated information need. These propositions draw upon concepts such as uncertainty, predictability, sensitivity and the valuation of information sources. Conclusion. An individual's understanding of personal, anticipated information need and how this understanding guides the acquisition and management of personal information will determine the effectiveness of that collection.

    16. Narrating personality change.

      Science.gov (United States)

      Lodi-Smith, Jennifer; Geise, Aaron C; Roberts, Brent W; Robins, Richard W

      2009-03-01

      The present research investigated the longitudinal relations between personality traits and narratives. Specifically, the authors examined how individual differences in 170 college students' narratives of personality change (a) were predicted by personality traits at the beginning of college, (b) related to actual changes and perceived changes in personality traits during college, and (c) related to changes in emotional health during college. Individual differences in narratives of personality trait change told in the 4th year of college fell into 2 dimensions: affective processing, characterized by positive emotions, and exploratory processing, characterized by meaning making and causal processing. Conscientious, open, and extraverted freshmen told exploratory stories of change as seniors. Emotionally healthy freshmen told stories of change that were high in positive affect. Both positive affective and exploratory stories corresponded to change in emotional stability and conscientiousness during college above and beyond the effects of perceived changes in these traits. In addition, both positive affective and exploratory narratives corresponded to increases in emotional health during college independent of the effects of changes in personality traits. These findings improve our understanding of how individuals conceptualize their changing identity over time.

    17. Verifying for Superior Person and Petty Person%君子小人考

      Institute of Scientific and Technical Information of China (English)

      2015-01-01

      君子和小人是中国传统文化中以道德区分好人和坏人的一般标准。笔者通过分析古籍,认为君子和小人的区分,还有除道德层面以外的社会地位、称谓、夫妻关系和智愚等方面的外延。%Superior Person or Petty Person is the general standard to distinguish good or bad person in the Chi-nese traditional culture. Through the analysis of ancient books, the author proposes that the distinction of supe-rior person and petty person is not only the moral aspect, but also has extension of the social status, addressing people, relationship between husband and wife, and wisdom and fool, etc.

    18. Personal Identity Online

      DEFF Research Database (Denmark)

      Rodogno, Raffaele

      2012-01-01

      Philosophers concerned with the question of personal identity have typically been asking the so-called re-identification question: what are the conditions under which a person at one point in time is properly re-identified at another point in time? This is a rather technical question. In our...... everyday interactions, however, we do raise a number of personal identity questions that are quite distinct from it. In order to explore the variety of ways in which the Internet may affect personal identity, I propose in this study to broaden the typical philosophical horizon to other more mundane senses...... of the question. In Section 2, I describe a number of possible meanings of personal identity observed in everyday contexts and more philosophical ones. With some caveats, I argue that it is the specific context in which the question arises that disambiguates the meaning of the question. Online contexts are novel...

    19. Personalized persuasion: tailoring persuasive appeals to recipients' personality traits.

      Science.gov (United States)

      Hirsh, Jacob B; Kang, Sonia K; Bodenhausen, Galen V

      2012-06-01

      Persuasive messages are more effective when they are custom-tailored to reflect the interests and concerns of the intended audience. Much of the message-framing literature has focused on the advantages of using either gain or loss frames, depending on the motivational orientation of the target group. In the current study, we extended this research to examine whether a persuasive appeal's effectiveness can be increased by aligning the message framing with the recipient's personality profile. For a single product, we constructed five advertisements, each designed to target one of the five major trait domains of human personality. In a sample of 324 survey respondents, advertisements were evaluated more positively the more they cohered with participants' dispositional motives. These results suggest that adapting persuasive messages to the personality traits of the target audience can be an effective way of increasing the messages' impact, and highlight the potential value of personality-based communication strategies.

    20. PERSONAL VERSUS MASS COMMUNICATION

      OpenAIRE

      Girboveanu Sorina

      2007-01-01

      From the comparison of the various aspects of advertising and personal selling, it can be seen that personal selling is a more effective and powerful communication tool than advertising, but advertising is more time and cost efficient than personal selling. Thus advertising and personal selling are tools at the disposal of a marketer and subjects to a firm’s overall objectives.

    1. Spraguea lophii (Microsporidia) parasitizing blackbellied angler (Lophius budegassa) and angler (L. piscatorius) in European Atlantic waters

      Science.gov (United States)

      Landa, Jorge; Cañás, Lucía

      2017-12-01

      Blackbellied angler (Lophius budegassa) and angler (L. piscatorius) are two important commercial species in the Bay of Biscay and the European fisheries infected by the microsporidian parasite Spraguea lophii. Samplings of both anglerfish were performed from a nine year time-series (2006-2014) from commercial fleet and bottom research surveys operating in southern Bay of Biscay and Galician waters (ICES Div. VIIIc and IXa2), Celtic Sea (Div. VIIh), south-western Ireland (Div. VIIj and VIIk), western Ireland and Porcupine Bank (Div. VIIb and VIIc). Length and sex of fish and presence or absence of the parasite were recorded. The prevalence by Spraguea was used to analyse the infection level. The role of each variable (fish length, fish sex, geographical area and year) and the interactions among them on the Spraguea prevalence were analyzed by using a binomial GLM. Area and fish length had a more relevant effect on the infestation of both anglerfish, while the impact of the year and fish sex was less evident. The Spraguea prevalence by area ranged between 11% and 52% in L. budegassa and between 39% and 66% in L. piscatorius. This is the first study in which the prevalence of this parasite in L. budegassa is analyzed in several areas and inter-annually compared. A non-linear relationship with a sharp increment of the prevalence with fish length was obtained in both anglerfish. The results were compared with those from the scarce previous studies and discussed.

    2. Personality-Related Problems and the Five-Factor Model of Personality

      OpenAIRE

      Boudreaux, Michael

      2014-01-01

      This research identifies a broad and inclusive set of personality-related problems and examines their empirical associations with both the high and low poles of the five-factor model of personality (FFM). McCrae, Widiger, and colleagues (e.g., McCrae, 1994; McCrae, Löckenhoff, & Costa, 2005; Widiger, Costa, & McCrae, 2002, 2012) have proposed that individuals with particular personality traits may be predisposed to particular kinds of problems in life, and suggested that the FFM serve as a ba...

    3. Translating Personality Psychology to Help Personalize Preventive Medicine for Young-Adult Patients

      Science.gov (United States)

      Israel, Salomon; Moffitt, Terrie E.; Belsky, Daniel W.; Hancox, Robert J.; Poulton, Richie; Roberts, Brent; Thomson, W. Murray; Caspi, Avshalom

      2014-01-01

      The rising number of newly insured young adults brought on by healthcare reform will soon increase demands on primary-care physicians. Physicians will face more young-adult patients which presents an opportunity for more prevention-oriented care. In the current study, we evaluated whether brief observer reports of young adults’ personality traits could predict which individuals would be at greater risk for poor health as they entered midlife. Following the Dunedin Study cohort of 1,000 individuals, we show that very brief measures of young adults’ personalities predicted their midlife physical health across multiple domains (metabolic abnormalities, cardiorespiratory fitness, pulmonary function, periodontal disease, and systemic inflammation). Individuals scoring low on the traits of Conscientiousness and Openness-to-Experience went on to develop poorer health even after accounting for preexisting differences in education, socioeconomic status, smoking, obesity, self-reported health, medical conditions, and family medical history. Moreover, personality ratings from peer informants who knew participants well, and from a nurse and receptionist who had just met participants for the first time, predicted health decline from young adulthood to midlife despite striking differences in level of acquaintance. Personality effect sizes were on par with other well-established health-risk factors such as socioeconomic status, smoking, and self-reported health. We discuss the potential utility of personality measurement to function as an inexpensive and accessible tool for healthcare professionals to personalize preventive medicine. Adding personality information to existing healthcare electronic infrastructures could also advance personality theory by generating opportunities to examine how personality processes influence doctor-patient communication, health service use, and patient outcomes. PMID:24588093

    4. [DSM-5 classification of personality disorders in older persons

      NARCIS (Netherlands)

      Alphen, S.P. van; Rossi, G.; Dierckx, E.; Oude Voshaar, R.C.

      2014-01-01

      BACKGROUND: Although it is generally agreed that personality disorders are an important topic in old-age psychiatry, DSM-5 has paid relatively little attention to older persons affected with this severe mental disorder. AIM: To look closely and carefully at several aspects of the way in which DSM-5

    5. Maladaptive Personality Trait Models: Validating the Five-Factor Model Maladaptive Trait Measures With the Personality Inventory for DSM-5 and NEO Personality Inventory.

      Science.gov (United States)

      Helle, Ashley C; Mullins-Sweatt, Stephanie N

      2017-05-01

      Eight measures have been developed to assess maladaptive variants of the five-factor model (FFM) facets specific to personality disorders (e.g., Five-Factor Borderline Inventory [FFBI]). These measures can be used in their entirety or as facet-based scales (e.g., FFBI Affective Dysregulation) to improve the comprehensiveness of assessment of pathological personality. There are a limited number of studies examining these scales with other measures of similar traits (e.g., DSM-5 alternative model). The current study examined the FFM maladaptive scales in relation to the respective general personality traits of the NEO Personality Inventory-Revised and the pathological personality traits of the DSM-5 alternative model using the Personality Inventory for DSM-5. The results indicated the FFM maladaptive trait scales predominantly converged with corresponding NEO Personality Inventory-Revised, and Personality Inventory for DSM-5 traits, providing further validity for these measures as extensions of general personality traits and evidence for their relation to the pathological trait model. Benefits and applications of the FFM maladaptive scales in clinical and research settings are discussed.

    6. Personalization and perceived personal relevance in computer-tailored persuasion in smoking cessation.

      Science.gov (United States)

      Dijkstra, Arie; Ballast, Karien

      2012-02-01

      In most computer-tailored interventions, the recipient's name is used to personalize the information. This is done to increase the process of persuasion but few empirical data exist that support this notion. An experimental laboratory study was conducted to test the effects of mentioning the participants name and to study whether it was related to the depth of processing in a 2 (personalization/standard) × 2 (weak/strong arguments) design. Over 120 student smokers were randomly assigned to one of the four experimental conditions in which they read smoking cessation messages offering (pre-tested) strong or weak arguments. Personalization was applied by mentioning the recipient's first name three times in the text. The intention to quit smoking was the dependent variable. Personalization increased persuasion when perceived personal relevance was high, but it decreased persuasion when perceived personal relevance was low. The effects on persuasion were only present in the case of strong arguments. Personalization is not always effective, and it may even lead to less persuasion. Therefore, this often used way to tailor messages must be applied with care. ©2011 The British Psychological Society.

    7. Personal Reflections

      Indian Academy of Sciences (India)

      Home; Journals; Resonance – Journal of Science Education. Personal Reflections. Articles in Resonance – Journal of Science Education. Volume 6 Issue 3 March 2001 pp 90-93 Personal Reflections. Why did I opt for Career in Science? Jayant V Narlikar · More Details Fulltext PDF. Volume 9 Issue 8 August 2004 pp 89-89 ...

    8. NDE of stainless steel and on-line leak monitoring of LWRs. Annual report, October 1984-September 1985. Volume 2

      International Nuclear Information System (INIS)

      Kupperman, D.S.; Claytor, T.N.; Mathieson, T.; Prine, D.W.

      1986-02-01

      This progress report summarizes work performed by the Argonne National Laboratory and GARD, Inc. (Division of Chamberlain Mfg. Corp.) as subcontractor on NDE of stainless steel and on-line leak monitoring of LWRs during the 12 months from October 1984 to September 1985. 15 refs., 36 figs

    9. 75 FR 54854 - Wooden Bedroom Furniture From the People's Republic of China: Partial Rescission of Antidumping...

      Science.gov (United States)

      2010-09-09

      ... Hospitality Product Mfg., Co., Ltd. Shanghai Kent Furniture Co., Ltd. Shanghai Season Industry & Commerce Co... International, Ltd., Super Art Furniture Co., Ltd., Artwork Metal and Plastic Co., Ltd., Jibson Industries, Ltd... Hospitality, Inc. Changshu HTC Import & Export Co., Ltd. Chuan Fa Furniture Factory Contact Co., Ltd. Decca...

    10. Personality disorders

      DEFF Research Database (Denmark)

      Simonsen, Sebastian; Heinskou, Torben; Sørensen, Per

      2017-01-01

      BACKGROUND: In this naturalistic study, patients with personality disorders (N = 388) treated at Stolpegaard Psychotherapy Center, Mental Health Services, Capital Region of Denmark were allocated to two different kinds of treatment: a standardized treatment package with a preset number of treatment...... characteristics associated with clinicians' allocation of patients to the two different personality disorder services. METHODS: Patient characteristics across eight domains were collected in order to study whether there were systematic differences between patients allocated to the two different treatments....... Patient characteristics included measures of symptom severity, personality pathology, trauma and socio-demographic characteristics. Significance testing and binary regression analysis were applied to identify important predictors. RESULTS: Patient characteristics on fifteen variables differed...

    11. Career Self-Efficacy and Personality: Linking Career Confidence and the Healthy Personality

      Science.gov (United States)

      Borgen, Fred H.; Betz, Nancy E.

      2008-01-01

      This article extends recent work on the relationship between personality and career self-efficacy by examining relationships across two new inventories with scales for identifying human strengths. The Healthy Personality Inventory (HPI) has 17 content scales tapping an array of positive personality measures. The CAPA Confidence Inventory (CCI) has…

    12. Levels of Personality Functioning Scale Self-Report Validation Journal of Personality Assessment

      OpenAIRE

      Good, Evan; Hopwood, Christopher; Morey, Leslie

      2017-01-01

      Validation of the Levels of Personality Functioning Scale - Self-Report. Results suggest that the measure has a robust single dimension and that it correlates in a very general manner with a wide range of maladaptive personality variables, consistent with its purpose as a measure of non-specific personality pathology.

    13. Personality Psychology and Economics

      OpenAIRE

      Almlund, Mathilde; Duckworth, Angela Lee; Heckman, James J.; Kautz, Tim

      2011-01-01

      This paper explores the power of personality traits both as predictors and as causes of academic and economic success, health, and criminal activity. Measured personality is interpreted as a construct derived from an economic model of preferences, constraints, and information. Evidence is reviewed about the "situational specificity" of personality traits and preferences. An extreme version of the situationist view claims that there are no stable personality traits or preference parameters tha...

    14. Multimethod, contextualized personality assessment

      OpenAIRE

      Hopwood, CJ; Bleidorn, W

      2017-01-01

      © 2017 European Association of Personality Psychology. Lievens asserted that personality researchers should (a) use multiple methods, in contrast to traditional over-reliance on self-report and (b) move past highly general and context-free assessments to more careful consideration of the situations within which personality predictions are made. These points are with reference to personnel selection settings using the broader framework of Trait Activation Theory. Like most personality research...

    15. Personal anticipated information need

      OpenAIRE

      H. Bruce

      2005-01-01

      Background. The role of personal information collections is a well known feature of personal information management. The World Wide Web has introduced to such collections ideas such as filing Web pages or noting their existence in 'Bookmarks' and 'Favourites'. Argument. It is suggested that personal information collections are created in anticipation of some future need for that information-personal, anticipated information need, which also underlies the design of formal information systems. ...

    16. Specific personality traits and general personality dysfunction as predictors of the presence and severity of personality disorders in a clinical sample

      NARCIS (Netherlands)

      Berghuis, H.; Kamphuis, J.H.; Verheul, R.

      2014-01-01

      This study examined the associations of specific personality traits and general personality dysfunction in relation to the presence and severity of Diagnostic and Statistical Manual of Mental Disorders (4th ed. [DSM-IV]; American Psychiatric Association, 1994) personality disorders in a Dutch

    17. Development of personality and the remission and onset of personality pathology.

      Science.gov (United States)

      Wright, Aidan G C; Pincus, Aaron L; Lenzenweger, Mark F

      2011-12-01

      The current study used the Longitudinal Study of Personality Disorders data set (Lenzenweger, 1999) to examine the development of personality traits in the context of the remission and onset of personality disorder (PD) symptoms. Despite high levels of stability, past research on the development of basic personality traits has also found a mean trend toward increased maturity and that individuals vary in their trajectories of trait development. Research on PD change has shown a similar pattern. We employed individual growth curve modeling to examine the relationship between personality trait development and PD symptom course. We found that both are indeed related and that remission in PD symptoms is associated with patterns of trait development associated with more rapid maturity. In contrast, deviating from the mean of trait development either through no change (i.e., stagnation) or change in the opposite direction (i.e., regression) was associated with developing PD symptoms over the course of the study.

    18. The Value of Personal Data

      OpenAIRE

      Lieshout , Marc ,

      2015-01-01

      Part 1: Invited Keynote Papers; International audience; This chapter discusses the value of personal data from two complementary perspectives: the value of personal data for firms and the value of personal data for individuals. The chapter starts with a short introduction into the rise of personal data markets – markets basically driven by the economic exploitation of personal data. Then the chapter discusses how firms asses the value of personal data. This can be done from different angles, ...

    19. Cerebellum and personality traits.

      Science.gov (United States)

      Petrosini, Laura; Cutuli, Debora; Picerni, Eleonora; Laricchiuta, Daniela

      2015-02-01

      Personality traits are multidimensional traits comprising cognitive, emotional, and behavioral characteristics, and a wide array of cerebral structures mediate individual variability. Differences in personality traits covary with brain morphometry in specific brain regions. A cerebellar role in emotional and affective processing and on personality characteristics has been suggested. In a large sample of healthy subjects of both sexes and differently aged, the macro- and micro-structural variations of the cerebellum were correlated with the scores obtained in the Temperament and Character Inventory (TCI) by Cloninger. Cerebellar volumes were associated positively with Novelty Seeking scores and negatively with Harm Avoidance scores. Given the cerebellar contribution in personality traits and emotional processing, we investigated the cerebellar involvement even in alexithymia, construct of personality characterized by impairment in cognitive, emotional, and affective processing. Interestingly, the subjects with high alexithymic traits had larger volumes in the bilateral Crus 1. The cerebellar substrate for some personality dimensions extends the relationship between personality and brain areas to a structure up to now thought to be involved mainly in motor and cognitive functions, much less in emotional processes and even less in personality individual differences. The enlarged volumes of Crus 1 in novelty seekers and alexithymics support the tendency to action featuring both personality constructs. In fact, Novelty Seeking and alexithymia are rooted in behavior and inescapably have a strong action component, resulting in stronger responses in the structures more focused on action and embodiment, as the cerebellum is.

    20. TH-C-BRD-12: Robust Intensity Modulated Proton Therapy Plan Can Eliminate Junction Shifts for Craniospinal Irradiation

      International Nuclear Information System (INIS)

      Liao, L; Jiang, S; Li, Y; Wang, X; Li, H; Zhu, X; Sahoo, N; Gillin, M; Mahajan, A; Grosshans, D; Zhang, X; Lim, G

      2014-01-01

      Purpose: The passive scattering proton therapy (PSPT) technique is the commonly used radiotherapy technique for craniospinal irradiation (CSI). However, PSPT involves many numbers of junction shifts applied over the course of treatment to reduce the cold and hot regions caused by field mismatching. In this work, we introduced a robust planning approach to develop an optimal and clinical efficient techniques for CSI using intensity modulated proton therapy (IMPT) so that junction shifts can essentially be eliminated. Methods: The intra-fractional uncertainty, in which two overlapping fields shift in the opposite directions along the craniospinal axis, are incorporated into the robust optimization algorithm. Treatment plans with junction sizes 3,5,10,15,20,25 cm were designed and compared with the plan designed using the non-robust optimization. Robustness of the plans were evaluated based on dose profiles along the craniospinal axis for the plans applying 3 mm intra-fractional shift. The dose intra-fraction variations (DIV) at the junction are used to evaluate the robustness of the plans. Results: The DIVs are 7.9%, 6.3%, 5.0%, 3.8%, 2.8% and 2.2%, for the robustly optimized plans with junction sizes 3,5,10,15,20,25 cm. The DIV are 10% for the non-robustly optimized plans with junction size 25 cm. The dose profiles along the craniospinal axis exhibit gradual and tapered dose distribution. Using DIVs less than 5% as maximum acceptable intrafractional variation, the overlapping region can be reduced to 10 cm, leading to potential reduced number of the fields. The DIVs are less than 5% for 5 mm intra-fractional shifts with junction size 25 cm, leading to potential no-junction-shift for CSI using IMPT. Conclusion: This work is the first report of the robust optimization on CSI based on IMPT. We demonstrate that robust optimization can lead to much efficient carniospinal irradiation by eliminating the junction shifts

    1. Personalized professional content recommendation

      Science.gov (United States)

      Xu, Songhua

      2015-10-27

      A personalized content recommendation system includes a client interface configured to automatically monitor a user's information data stream transmitted on the Internet. A hybrid contextual behavioral and collaborative personal interest inference engine resident to a non-transient media generates automatic predictions about the interests of individual users of the system. A database server retains the user's personal interest profile based on a plurality of monitored information. The system also includes a server programmed to filter items in an incoming information stream with the personal interest profile and is further programmed to identify only those items of the incoming information stream that substantially match the personal interest profile.

    2. Psychopathy/antisocial personality disorder conundrum.

      Science.gov (United States)

      Ogloff, James R P

      2006-01-01

      Psychopathy has traditionally been characterised as a disorder primarily of personality (particularly affective deficits) and, to a lesser extent, behaviour. Although often used interchangeably, the diagnostic constructs of psychopathy, antisocial personality disorder, and dissocial personality disorder are distinct. In this article, the relevant historical and contemporary literature concerning psychopathy is briefly reviewed. The diagnostic criteria for psychopathy, antisocial personality disorder, and dissocial personality disorder are compared. Consideration is given to the assessment, prevalence, and implications of psychopathy for violence risk and treatment efficacy. The DSM-IV-TR criteria for antisocial personality disorder, in particular, are largely behaviourally based. The ICD criteria for dissocial personality disorder, while paying more attention to affective deficits, also do not represent the broad personality and behavioural components of psychopathy. Since 1980, a great deal of research on these disorders has been conducted, using the Hare Psychopathy Checklist, Revised (PCL-R). The PCL-R assesses both personality (interpersonal and affective) and behavioural (lifestyle and antisocial) deficits. As such, the research and clinical implications of psychopathy, as operationalised by the PCL-R, cannot be readily extrapolated to the diagnoses of antisocial personality disorder and dissocial personality disorder. As currently construed, the diagnosis of antisocial personality disorder grossly over-identifies people, particularly those with offence histories, as meeting the criteria for the diagnosis. For example, research shows that between 50% and 80% of prisoners meet the criteria for a diagnosis of antisocial personality disorder, yet only approximately 15% of prisoners would be expected to be psychopathic, as assessed by the PCL-R. As such, the characteristics and research findings drawn from the psychopathy research may not be relevant for those

    3. Viewing relational aggression through multiple lenses: temperament, personality, and personality pathology.

      Science.gov (United States)

      Tackett, Jennifer L; Kushner, Shauna C; Herzhoff, Kathrin; Smack, Avante J; Reardon, Kathleen W

      2014-08-01

      Dispositional trait frameworks offer great potential to elucidate the nature and development of psychopathology, including the construct of relational aggression. The present study sought to explore the dispositional context of relational aggression across three dispositional frameworks: temperament, personality, and personality pathology. Participants comprised a large community sample of youth, aged 6 to 18 years (N = 1,188; 51.2% female). Ratings of children's relational aggression, temperament, personality, and personality pathology traits were obtained through parent report (86.3% mothers). Results showed convergence and divergence across these three dispositional frameworks. Like other antisocial behavior subtypes, relational aggression generally showed connections with traits reflecting negative emotionality and poor self-regulation. Relational aggression showed stronger connections with temperament traits than with personality traits, suggesting that temperament frameworks may capture more relationally aggressive content. Findings at the lower order trait level help differentiate relational aggression from other externalizing problems by providing a more nuanced perspective (e.g., both sociability and shyness positively predicted relational aggression). In addition, there was little evidence of moderation of these associations by gender, age, or age2, and findings remained robust even after controlling for physical aggression. Results are discussed in the broader context of conceptualizing relational aggression in an overarching personality-psychopathology framework.

    4. Personality and Sexual Orientation

      Science.gov (United States)

      Harris, Charles M.

      2004-01-01

      Bases for individual acceptance and cultural integration of gays and lesbians were investigated by assessing qualities of personality among four participant groups: Heterosexual females, heterosexual males, homosexual females, and homosexual males. Personality was operationally defined as personal qualities and characteristics associated with…

    5. Personality and Longevity: Knowns, Unknowns, and Implications for Public Health and Personalized Medicine

      Science.gov (United States)

      Chapman, Benjamin P.; Roberts, Brent; Duberstein, Paul

      2011-01-01

      We review evidence for links between personality traits and longevity. We provide an overview of personality for health scientists, using the primary organizing framework used in the study of personality and longevity. We then review data on various aspects of personality linked to longevity. In general, there is good evidence that higher level of conscientiousness and lower levels of hostility and Type D or “distressed” personality are associated with greater longevity. Limited evidence suggests that extraversion, openness, perceived control, and low levels of emotional suppression may be associated with longer lifespan. Findings regarding neuroticism are mixed, supporting the notion that many component(s) of neuroticism detract from life expectancy, but some components at some levels may be healthy or protective. Overall, evidence suggests various personality traits are significant predictors of longevity and points to several promising directions for further study. We conclude by discussing the implications of these links for epidemiologic research and personalized medicine and lay out a translational research agenda for integrating the psychology of individual differences into public health and medicine. PMID:21766032

    6. Treatment of personality disorder.

      Science.gov (United States)

      Bateman, Anthony W; Gunderson, John; Mulder, Roger

      2015-02-21

      The evidence base for the effective treatment of personality disorders is insufficient. Most of the existing evidence on personality disorder is for the treatment of borderline personality disorder, but even this is limited by the small sample sizes and short follow-up in clinical trials, the wide range of core outcome measures used by studies, and poor control of coexisting psychopathology. Psychological or psychosocial intervention is recommended as the primary treatment for borderline personality disorder and pharmacotherapy is only advised as an adjunctive treatment. The amount of research about the underlying, abnormal, psychological or biological processes leading to the manifestation of a disordered personality is increasing, which could lead to more effective interventions. The synergistic or antagonistic interaction of psychotherapies and drugs for treating personality disorder should be studied in conjunction with their mechanisms of change throughout the development of each. Copyright © 2015 Elsevier Ltd. All rights reserved.

    7. The person within: memory codes for persons and traits using fMRI repetition suppression.

      Science.gov (United States)

      Heleven, Elien; Van Overwalle, Frank

      2016-01-01

      Neuroimaging studies on trait inference demonstrated that the ventral medial prefrontal cortex (mPFC) houses neural representations of memory codes for traits . In this study, we investigate the neural code not only of traits, but also of persons who exemplify these traits. We used repetition suppression, which is a rapid suppression of the neuroimaging signal upon repeated presentation of the same stimulus or core stimulus characteristics-in this case, the implied trait and person. Participants inferred familiar person's traits. At each trial, a critical (target) sentence described a behavior that implied a trait, and was preceded by a (prime) sentence that implied the same trait and portrayed the same person, the same trait but portrayed a different person or did not imply a trait and portrayed a different person. As predicted, we found partly overlapping repetition suppression areas in the ventral mPFC when persons and traits were repeated, indicating that not only traits but also familiar persons have a neural code in the ventral mPFC. We also found a negative correlation between activation when reading about a new person and participants' social network size, indicating that experience with larger social groups results in less recruitment of a person code. © The Author (2015). Published by Oxford University Press. For Permissions, please email: journals.permissions@oup.com.

    8. Police personality : and the relationship between personality and preferences for conflict resolution tactics

      OpenAIRE

      Abrahamsen, Solveig

      2006-01-01

      Do police officers possess certain personality characteristics that make them unique compared to the non-police population? This question has been the subject of an extensive line of research. Several researchers have found evidence of a so-called police personality, while other researchers have failed to detect personality differences between the police and the public. Also, some researchers have found that officers differ from each other in terms of job performance, and that personality dif...

    9. Dimensions of personality pathology in adolescents: Relations to DSM-IV personality disorder symptoms

      OpenAIRE

      Tromp, N.B.; Koot, H.M.

      2009-01-01

      The aim of the present study was to relate and compare two approaches to personality pathology in adolescents. Dimensions of personality pathology, assessed by the Dimensional Assessment of Personality Pathology-Basic Questionnaire for Adolescents (DAPP-BQ-A; Tromp & Koot, 2008), were related to DSM-IV personality disorder (PD) symptoms in 168 adolescents referred for mental health services. Correlational analyses revealed that the DAPP-BQ-A higher- and lower-order dimensions were related to ...

    10. Personal Freedom beyond Limits

      Directory of Open Access Journals (Sweden)

      Juan Fernando Sellés

      2013-07-01

      Full Text Available In this work we distinguish between freedom in the human manifestations (intelligence, will,actions and personal freedom in the personal intimacy. This second is beyond the freedom reached bythe classic and modern thought, since it takes root in the personnel act of being. Because of it, it is not possible to characterize this freedom like the classic description as ‘domain over the own acts’, becauseit is a description of ‘categorial’ order; neither like present day ‘autonomy’ or ‘independence’, becausethe existence of one person alone is impossible, since ‘person’ means relation, personal free openingto other persons, description of the ‘transcendental’ order and, therefore, to the margin of limits.

    11. Personal piety in Nordic heathenism

      Directory of Open Access Journals (Sweden)

      Åke V. Ström

      1990-01-01

      Full Text Available Usually, Nordic heathenism is thought of as a fairy-tale or as an impersonal, collective event. Sacrifice (blót and ethics appear to be the main facts. Was there anything at all like piety, and could it, in this case, be spoken of as personal? The inhabitant of the North stands out as a more collectively thinking person, attached to dynasty, housecarls and family. However, there are a couple of examples in the texts of a "personal faith" and an interest in "the individual or his soul or destiny". It is quite clear, that the collective and impersonal traits in old Norse religion were far more prominent than in the religious currents of today, but there was in Nordic paganism a personal piety, too. It appeared not only in personal opinion and personal means of expression, but also in daily life as well. The single peasant, Viking, fisherman, artisan, housewife, was in his or her everyday work totally dependent on the blessing of the gods and on protection from the attacks of the demons. He who succeeded enjoyed this personal success because of personal sacrifices, personal fortune and personal blessing.

    12. Person-Centered Transition Planning.

      Science.gov (United States)

      Miner, Craig A.; Bates, Paul E.

      1997-01-01

      Describes a person-centered planning approach for involving students with disabilities and their families in the transition planning process. Components of person-centered planning are discussed, including development of a personal profile, identification of future lifestyle preferences, action steps and responsible parties, and necessary changes…

    13. Multi-Family Groups for Multi-Stressed Families: Initial Outcomes and Future Implications

      Science.gov (United States)

      Jackson, Jerrold M.

      2015-01-01

      Purpose: To examine the influence of caregiver stress on attendance among urban families involved in a multiple family group (MFG) intervention, as well as pre/post changes in childhood behavioral difficulties, caregiver stress, caregiver depressive symptoms, caregiver coping by substance use, and caregiver motivation to change. Methods:…

    14. Prototype Matching of Personality Disorders with the Dimensional Clinical Personality Inventory

      Directory of Open Access Journals (Sweden)

      Lucas de Francisco Carvalho

      Full Text Available ABSTRACT This study aimed to investigate validity evidence of the Dimensional Clinical Personality Inventory (IDCP through the expected associations with the five-factor model (FFM, especially in regard to the prototype matching of personality disorders. A non-clinical sample (N=94, aged between 19 and 55 years (M=25.5; SD=7.35, and 59.6% male, answered the IDCP and the NEO-PI-R for the assessment of 12 dimensions related to personality disorders and evaluation of five personality dimensions, respectively. The results pointed to consistent empirical relations between the dimensions of the IDCP and the NEO-PI-R, as well as between the diagnostic categories of DSM-IV-TR based on the FFM and the IDCP dimensions.

    15. Personal Wellness Tools

      Science.gov (United States)

      ... of Personal Stories Peers Celebrating Art Peers Celebrating Music Be Vocal Support Locator DBSA In-Person Support ... With this tool, you can track key health trends related to the following: Overall mood Mood disorder ...

    16. Gambling and Personality Dimensions

      DEFF Research Database (Denmark)

      Odlaug, Brian Lawrence; Chamberlain, Samuel

      2014-01-01

      , which has further catalyzed a debate over the contribution of personality traits (rather than just personality disorders) to the manifestation and maintenance of psychiatric conditions such as Gambling Disorder. This selective review considers relationships between gambling and personality traits....... The possible existence of distinct subtypes of Gambling Disorder, defined via personality traits, is highlighted, along with consideration of whether objective neurocognitive markers could serve as proxy markers of ‘personality’ more amenable to scientific dissection rather than relying on questionnaire...

    17. The Personality Inventory Scales: a self-rating clinical instrument for diagnosis of personality disorder.

      Science.gov (United States)

      Burgess, J W

      1991-12-01

      A personality inventory was developed as an aid in securing history and beliefs relevant to the assessment of personality structure and the diagnosis of personality disorders. The inventory was developed by restating DSM diagnostic criteria in everyday language, rewording the resulting statements in the form of True/False questions, and placing these questions in a short, self-paced booklet which subjects could complete in about 15 minutes. The following assessments were made and discussed: construct validity, split-half reliability, test-retest reliability, comparison with a standardized interview, and comparison with actual clinical assessments. The personality inventory is discussed as a useful accompaniment to the diagnostic interview in clinical settings and for research into personality structure and personality disorders.

    18. Methods of Studying Persons.

      Science.gov (United States)

      Heinemann, Allen W.; Shontz, Franklin C.

      Conventional research strategies typically emphasize behavior-determining tendencies so strongly that the person as a whole is ignored. Research strategies for studying whole persons focus on symbolic structures, formulate specific questions in advance, study persons one at a time, use individualized measures, and regard participants as expert…

    19. Dimensions of personality pathology in adolescents: Relations to DSM-IV personality disorder symptoms

      NARCIS (Netherlands)

      Tromp, N.B.; Koot, H.M.

      2009-01-01

      The aim of the present study was to relate and compare two approaches to personality pathology in adolescents. Dimensions of personality pathology, assessed by the Dimensional Assessment of Personality Pathology-Basic Questionnaire for Adolescents (DAPP-BQ-A; Tromp & Koot, 2008), were related to

    20. Physicists develop more powerful tools to combat cancer

      CERN Multimedia

      Antonella Del Rosso and Fabio Capello

      2012-01-01

      The tools physicists are currently sharing with doctors to defeat cancer are high-tech sensors for early detection and particles for use as sharp projectiles. The latest advances in medical physics and some of the most sophisticated devices for imaging, monitoring and treatment were presented at the ICTR-PHE 2012 conference. They will shape the future of advanced healthcare.   @font-face { font-family: "Cambria Math"; }@font-face { font-family: "Cambria"; }p.MsoNormal, li.MsoNormal, div.MsoNormal { margin: 0cm 0cm 0.0001pt; font-size: 12pt; font-family: Cambria; }p.MsoCommentText, li.MsoCommentText, div.MsoCommentText { margin: 0cm 0cm 0.0001pt; font-size: 10pt; font-family: Cambria; }span.MsoCommentReference { }a:link, span.MsoHyperlink { color: blue; text-decoration: underline; }a:visited, span.MsoHyperlinkFollowed { color: purple; text-decoration: underline; }span.CommentTextChar { }.MsoChpDefault { font-size: 10pt; font-family: Cambria; }div.WordSection1 { page: WordSection1; } So...

    1. The Five-Factor Model of Personality and Borderline Personality Disorder: A Genetic Analysis of Comorbidity

      NARCIS (Netherlands)

      Distel, M.A.; Trull, T.J.; Willemsen, G.; Vink, J.M.; Derom, C.A.; Lynskey, M.; Martin, N.G.; Boomsma, D.I.

      2009-01-01

      Background: Recently, the nature of personality disorders and their relationship with normal personality traits has received extensive attention. The five-factor model (FFM) of personality, consisting of the personality traits neuroticism, extraversion, openness to experience, agreeableness, and

    2. Inflexible Functional Connectivity of the Dorsal Anterior Cingulate Cortex in Adolescent Major Depressive Disorder.

      Science.gov (United States)

      Ho, Tiffany C; Sacchet, Matthew D; Connolly, Colm G; Margulies, Daniel S; Tymofiyeva, Olga; Paulus, Martin P; Simmons, Alan N; Gotlib, Ian H; Yang, Tony T

      2017-11-01

      Recent evidence suggests that anterior cingulate cortex (ACC) maturation during adolescence contributes to or underlies the development of major depressive disorder (MDD) during this sensitive period. The ACC is a structure that sits at the intersection of several task-positive networks (eg, central executive network, CEN), which are still developing during adolescence. While recent work using seed-based approaches indicate that depressed adolescents show limited task-evoked vs resting-state connectivity (termed 'inflexibility') between the ACC and task-negative networks, no study has used network-based approaches to investigate inflexibility of the ACC in task-positive networks to understand adolescent MDD. Here, we used graph theory to compare flexibility of network-level topology in eight subregions of the ACC (spanning three task-positive networks) in 42 unmedicated adolescents with MDD and 53 well-matched healthy controls. All participants underwent fMRI scanning during resting state and a response inhibition task that robustly engages task-positive networks. Relative to controls, depressed adolescents were characterized by inflexibility in local efficiency of a key ACC node in the CEN: right dorsal anterior cingulate cortex/medial frontal gyrus (R dACC/MFG). Furthermore, individual differences in flexibility of local efficiency of R dACC/MFG significantly predicted inhibition performance, consistent with current literature demonstrating that flexible network organization affords successful cognitive control. Finally, reduced local efficiency of dACC/MFG during the task was significantly associated with an earlier age of depression onset, consistent with prior work suggesting that MDD may alter functional network development. Our results support a neurodevelopmental hypothesis of MDD wherein dysfunctional self-regulation is potentially reflected by altered ACC maturation.

    3. Cerebral Responses to Vocal Attractiveness and Auditory Hallucinations in Schizophrenia: A Functional MRI Study

      Directory of Open Access Journals (Sweden)

      Michihiko eKoeda

      2013-05-01

      Full Text Available Impaired self-monitoring and abnormalities of cognitive bias have been implicated as cognitive mechanisms of hallucination; regions fundamental to these processes including inferior frontal gyrus (IFG and superior temporal gyrus (STG are abnormally activated in individuals that hallucinate. A recent study showed activation in IFG-STG to be modulated by auditory attractiveness, but no study has investigated whether these IFG-STG activations are impaired in schizophrenia. We aimed to clarify the cerebral function underlying the perception of auditory attractiveness in schizophrenia patients. Cerebral activation was examined in 18 schizophrenia patients and 18 controls when performing Favourability Judgment Task (FJT and Gender Differentiation Task (GDT for pairs of greetings using event-related functional MRI. A full-factorial analysis revealed that the main effect of task was associated with activation of left IFG and STG. The main effect of Group revealed less activation of left STG in schizophrenia compared with controls, whereas significantly greater activation in schizophrenia than in controls was revealed at the left middle frontal gyrus (MFG, right temporo-parietal junction (TPJ, right occipital lobe, and right amygdala (p<0.05, FDR-corrected. A significant positive correlation was observed at the right TPJ and right MFG between cerebral activation under FJT minus GDT contrast and the score of hallucinatory behaviour on the Positive and Negative Symptom Scale. Findings of hypo-activation in the left STG could designate brain dysfunction in accessing vocal attractiveness in schizophrenia, whereas hyper-activation in the right TPJ and MFG may reflect the process of mentalizing other person’s behaviour by auditory hallucination by abnormality of cognitive bias.

    4. Correlation of neural activity with behavioral kinematics reveals distinct sensory encoding and evidence accumulation processes during active tactile sensing.

      Science.gov (United States)

      Delis, Ioannis; Dmochowski, Jacek P; Sajda, Paul; Wang, Qi

      2018-03-23

      Many real-world decisions rely on active sensing, a dynamic process for directing our sensors (e.g. eyes or fingers) across a stimulus to maximize information gain. Though ecologically pervasive, limited work has focused on identifying neural correlates of the active sensing process. In tactile perception, we often make decisions about an object/surface by actively exploring its shape/texture. Here we investigate the neural correlates of active tactile decision-making by simultaneously measuring electroencephalography (EEG) and finger kinematics while subjects interrogated a haptic surface to make perceptual judgments. Since sensorimotor behavior underlies decision formation in active sensing tasks, we hypothesized that the neural correlates of decision-related processes would be detectable by relating active sensing to neural activity. Novel brain-behavior correlation analysis revealed that three distinct EEG components, localizing to right-lateralized occipital cortex (LOC), middle frontal gyrus (MFG), and supplementary motor area (SMA), respectively, were coupled with active sensing as their activity significantly correlated with finger kinematics. To probe the functional role of these components, we fit their single-trial-couplings to decision-making performance using a hierarchical-drift-diffusion-model (HDDM), revealing that the LOC modulated the encoding of the tactile stimulus whereas the MFG predicted the rate of information integration towards a choice. Interestingly, the MFG disappeared from components uncovered from control subjects performing active sensing but not required to make perceptual decisions. By uncovering the neural correlates of distinct stimulus encoding and evidence accumulation processes, this study delineated, for the first time, the functional role of cortical areas in active tactile decision-making. Copyright © 2018 Elsevier Inc. All rights reserved.

    5. Mindfulness Meditation Training and Executive Control Network Resting State Functional Connectivity: A Randomized Controlled Trial.

      Science.gov (United States)

      Taren, Adrienne A; Gianaros, Peter J; Greco, Carol M; Lindsay, Emily K; Fairgrieve, April; Brown, Kirk Warren; Rosen, Rhonda K; Ferris, Jennifer L; Julson, Erica; Marsland, Anna L; Creswell, J David

      Mindfulness meditation training has been previously shown to enhance behavioral measures of executive control (e.g., attention, working memory, cognitive control), but the neural mechanisms underlying these improvements are largely unknown. Here, we test whether mindfulness training interventions foster executive control by strengthening functional connections between dorsolateral prefrontal cortex (dlPFC)-a hub of the executive control network-and frontoparietal regions that coordinate executive function. Thirty-five adults with elevated levels of psychological distress participated in a 3-day randomized controlled trial of intensive mindfulness meditation or relaxation training. Participants completed a resting state functional magnetic resonance imaging scan before and after the intervention. We tested whether mindfulness meditation training increased resting state functional connectivity (rsFC) between dlPFC and frontoparietal control network regions. Left dlPFC showed increased connectivity to the right inferior frontal gyrus (T = 3.74), right middle frontal gyrus (MFG) (T = 3.98), right supplementary eye field (T = 4.29), right parietal cortex (T = 4.44), and left middle temporal gyrus (T = 3.97, all p < .05) after mindfulness training relative to the relaxation control. Right dlPFC showed increased connectivity to right MFG (T = 4.97, p < .05). We report that mindfulness training increases rsFC between dlPFC and dorsal network (superior parietal lobule, supplementary eye field, MFG) and ventral network (right IFG, middle temporal/angular gyrus) regions. These findings extend previous work showing increased functional connectivity among brain regions associated with executive function during active meditation by identifying specific neural circuits in which rsFC is enhanced by a mindfulness intervention in individuals with high levels of psychological distress. Clinicaltrials.gov,NCT01628809.

    6. Neuroanatomical profiles of bilingual children.

      Science.gov (United States)

      Archila-Suerte, Pilar; Woods, Elizabeth A; Chiarello, Christine; Hernandez, Arturo E

      2018-02-26

      The goal of the present study was to examine differences in cortical thickness, cortical surface area, and subcortical volume between bilingual children who are highly proficient in two languages (i.e., English and Spanish) and bilingual children who are mainly proficient in one of the languages (i.e., Spanish). All children (N = 49) learned Spanish as a native language (L1) at home and English as a second language (L2) at school. Proficiency of both languages was assessed using the standardized Woodcock Language Proficiency Battery. Five-minute high-resolution anatomical scans were acquired with a 3-Tesla scanner. The degree of discrepancy between L1 and L2 proficiency was used to classify the children into two groups: children with balanced proficiency and children with unbalanced proficiency. The groups were comparable on language history, parental education, and other variables except English proficiency. Values of cortical thickness and surface area of the transverse STG, IFG-pars opercularis, and MFG, as well as subcortical volume of the caudate and putamen, were extracted from FreeSurfer. Results showed that children with balanced bilingualism had thinner cortices of the left STG, left IFG, left MFG and a larger bilateral putamen, whereas unbalanced bilinguals showed thicker cortices of the same regions and a smaller putamen. Additionally, unbalanced bilinguals with stronger foreign accents in the L2 showed reduced surface areas of the MFG and STS bilaterally. The results suggest that balanced/unbalanced bilingualism is reflected in different neuroanatomical characteristics that arise from biological and/or environmental factors. Published 2018. This article is a U.S. Government work and is in the public domain in the USA.

    7. Identification of metformin poor responders, requiring supplemental insulin, during randomization of metformin versus insulin for the control of gestational diabetes mellitus.

      Science.gov (United States)

      Ashoush, Sherif; El-Said, Mourrad; Fathi, Hisham; Abdelnaby, Mohamed

      2016-06-01

      To evaluate glycemic control among women with gestational diabetes mellitus (GDM) under insulin versus metformin (with or without insulin supplementation), and to identify metformin poor responders requiring supplemental insulin. In Ain Shams University Hospital, mothers with 26-32-week GDM pregnancies, failing diet control, were randomized to receive metformin (n = 47) or insulin (n = 48). The primary outcome was glycemic control. Secondary outcomes included maternal weight, parameters predicting successful metformin monotherapy, neonatal hypoglycemia, and birthweight. Women using metformin (23.4% needing supplemental insulin) gained less weight (P metformin group was related to initial body mass index, HbA1c, oral glucose tolerance test (GTT), and first week mean glucose level. The 1-h glucose level during initial GTT (Hr1-GTT) and the mean fasting glucose level during the first week of therapy (Wk1-mFG) were the two independent parameters associated with requiring supplemental insulin. Women with Hr1-GTT >212 mg/dL and Wk1-mFG >95 mg/dL had a risk ratio of 58.6 (95%CI: 3.68-933.35, P = 0.004) and 11.5 (95%CI: 2.77-47.34,= 0.0008), respectively for needing supplemental insulin during the course of the study compared with women without. Metformin is an effective and safe alternative to insulin in GDM. Women using metformin (± supplemental insulin) had similar glycemic control, less weight gain, and similar rates of side-effects as those on insulin monotherapy. Insulin supplementation to metformin therapy was more likely with elevated Hr1-GTT and Wk1-mFG. © 2016 Japan Society of Obstetrics and Gynecology.

    8. Examination of personality characteristics in a Turkish sample: development of Basic Personality Traits Inventory.

      Science.gov (United States)

      Gençöz, Tülin; Öcül, Öznur

      2012-01-01

      The aim of the present study was to test the cross-cultural validity of the five-factor nature of personality. For this aim, an indigenous, psychometrically strong instrument measuring the basic personality dimensions within Turkish culture and language was developed through three consecutive studies. The first study aimed to reveal the adjectives that have been most frequently used to define people in the Turkish culture. In the second study, factor analysis of these personality characteristics revealed big five personality factors, along with the sixth factor, which had been called as the Negative Valence factor. The adjectives that most strongly represented and differentiated each factor constituted 45-item "Basic Personality Traits Inventory". Finally, in the third study, psychometric characteristics of the Basic Personality Traits Inventory were examined. Factor structure and psychometric properties of this instrument confirmed that five-factor nature of personality may not hold true in every culture.

    9. THE RELATIONSHIP BETWEEN THE PERSONALITY OF URBANITES AND CITY BRAND PERSONALITY - AN APPLICATION IN TURKEY

      Directory of Open Access Journals (Sweden)

      Nilsun Sariyer

      2017-02-01

      Full Text Available Brand personality claims that brands convey human characteristics. In this study, attempts have been made to determine the brand personality dimensions of cities based on the assumption that cities also have brand personality. Additionally, it has been studied whether or not urbanites reflect their own personality traits to brand personality characteristics of the city. In this descriptive study, data has been collected through face-to-face interviews. The sampling where stratified sampling is used – one method of random sampling – has been performed in Kayseri in Turkey. A total of 382 consumers have been reached. Factor and regression analyses have been used for data analysis. In conclusion, the city of Kayseri has five city brand dimensions: exhilarating, mature, androgen, traditional and sincere. In addition, it has also revealed that there is a relationship between the personalities of those who live in Kayseri and their city brand personalities. Those who live in metropolitan Kayseri and like taking risks – a criterion of extrovert personality – find Kayseri exhilarated and competent. In the light of this conclusion, it can be said that urbanites’ personalities should also be considered when forming city brand personality.

    10. Personality disorder

      DEFF Research Database (Denmark)

      Tyrer, Peter; Mulder, Roger; Crawford, Mike

      2010-01-01

      and to society, and interferes, usually negatively, with progress in the treatment of other mental disorders. We now have evidence that personality disorder, as currently classified, affects around 6% of the world population, and the differences between countries show no consistent variation. We are also getting......Personality disorder is now being accepted as an important condition in mainstream psychiatry across the world. Although it often remains unrecognized in ordinary practice, research studies have shown it is common, creates considerable morbidity, is associated with high costs to services...... increasing evidence that some treatments, mainly psychological, are of value in this group of disorders. What is now needed is a new classification that is of greater value to clinicians, and the WPA Section on Personality Disorders is currently undertaking this task....

    11. Personal, Anticipated Information Need

      Science.gov (United States)

      Bruce, Harry

      2005-01-01

      Background: The role of personal information collections is a well known feature of personal information management. The World Wide Web has introduced to such collections ideas such as filing Web pages or noting their existence in "Bookmarks" and "Favourites". Argument: It is suggested that personal information collections are…

    12. Personal Identity in Enhancement

      Directory of Open Access Journals (Sweden)

      Jana Podroužková

      2015-09-01

      Full Text Available The aim of this paper is to introduce the concept of human enhancement, its methods and its relation to personal identity. Also several approaches to personal identity will be described. Transhumanism is a special think tank supporting human enhancement through modern technologies and some of its representatives claim, that even great changes to human organisms will not affect their personal identity. I will briefly describe the most important means of human enhancment and consider the problem of personal identity for each of them separately.

    13. Recovery of personal neglect.

      Science.gov (United States)

      Iosa, Marco; Guariglia, Cecilia; Matano, Alessandro; Paolucci, Stefano; Pizzamiglio, Luigi

      2016-12-01

      Extrapersonal unilateral spatial neglect after stroke is associated to a poor rehabilitation outcome. Minor attention has been paid to the recovery of personal neglect, to its relationship with the recovery of extrapersonal neglect and of independency in activities of daily living. The present study aims at evaluating whether there is an association between recovery of extrapersonal and personal neglect. The secondary aim was to investigate if personal neglect may affect the effectiveness of neurorehabilitation in patients with subacute stroke. Observational study. Neurorehabilitation Hospital in Rome, Italy, inpatients. A sample of 49 patients with unilateral spatial neglect resulting from right ischemic cerebral infarction was enrolled in this study, divided into three subgroups according to the presence and the degree of personal neglect, and evaluated pre and postneurorehabilitation. Personal neglect was evaluated using Zoccolotti and Judica's Scale, extrapersonal neglect using Letter Cancellation Test, Barrage Test, Sentence Reading Test and Wundt-Jastrow Area Illusion Test. Barthel Index (BI), Rivermead Mobility Index, and Canadian Neurological Scale were also administered. Results showed the following: 1) recovery of personal neglect was not significantly correlated with that of extrapersonal neglect, despite both the disorders were ameliorated after a "non-specific" rehabilitation treatment; 2) personal neglect per se was not an additional negative prognostic factor in the rehabilitation findings. Our results suggested that the recoveries of the two types of neglect are independent from each other, and that the presence of personal neglect does not imply significant additional problems to the functional outcomes. Our study highlighted the need of novel tools to assess the presence and to improve the recovery of personal neglect.

    14. PHYSICS DIV. QUARTERLY REPORT, MAY, JUNE, JULY, 1950

      Energy Technology Data Exchange (ETDEWEB)

      Various

      1950-09-06

      The X-ray Spectrum Produced by 322 Mev Electrons Striking a Platinum Target. The differential energy spectrum of the photons produced by 322 Mev electrons striking a 20 mil platinum target was measured by observing the energy of 3467 pairs produced in a one mil thick lead foil in a Wilson cloud chamber in a magnetic field of 10,000 gauss. The spectrum is found to agree with that predicted by the Bethe-Heitler bremsstrahlung theory using a Thomas-Fermi model with suitable corrections for the thickness of the target. The energy of the 322 Mev electrons was determined by the spectrum of the photons observed in this experiment. Apparatus used and the experimental data and results obtained are reported fully in UCRL-660.

    15. Vibrio spp. ISOLATED FROM SHRIMPS AND WATER FROM A MARINE FARM IN PERNAMBUCO, BRAZIL Víbrios en el agua y en las gambas del mar (Litopenaeus vannamei, Boone, 1931 cultivado en Pernambuco Vibrio spp. ISOLADOS DE CAMARÃO E ÁGUA DE CULTIVO DE FAZENDA MARINHA EM PERNAMBUCO

      Directory of Open Access Journals (Sweden)

      Carlos André Bezerra Alves

      2009-12-01

      Full Text Available <div>Water and shrimp samples were collected monthly, during all cultivation phases, in three located farms at Pernambuco coast, on winter and summer, for Vibrio spp. quantification and identification. The counting’s were correlated, through mathematical models (P<0.05, with the variables season, water biochemical parameters, wet mount, histopathology exam, toxins presence and handling techniques used. Just the variable cultivation time interfered at total counting of Vibrio spp. in all samples were obtained countings that varied 0.1x 10 to 6.2 x 103 UFC/mL in water, of 7.0 x 10 to 8.2 x 105 UFC/g in powder-larva, of 1.1 x 10 to 1.1 x 105 UFC/mL in hemolymph and of 2.5 x 102 to 1.1 x 106UFC/g in hepatopancreas. The species V. mediterranei (1%, V. mimicus (1.25%, V. fischeri (4.25%, V. cincinnatiensis (4.25%, V. metschnikovii (4.25%, V. proteolyticus (5.5%, V. harveyi (5.5%, V. hollisae (5.5%, V. carchariae (7%, V. vulnificus (8.5%, V. damsela (8.5%, V. parahaemolyticus (13%, V. fluvialis (15%, V. anguillarum (16.5% were identified. It is concluded that the Vibrionaceae load increases proportionally with cultivation time, due to the organic matter increment, what can turn the susceptible animals to the infection for vibrios.div>>
      div>>KEY WORD: Vibrionaceae, Vibrio spp., shrimp and pond water.div> El agua y muestras de la gamba eran la publicación mensual reunido, durante todas las fases del cultivo, en tres granjas localizadas a la costa de Pernambuco, en invierno y verano, para la cuantificación e identificación el de Vibrio spp.. El contando fueron puestos en correlación, a través de los modelos matemáticos (P <0,05, con la estación de las variables, agua que los parámetros bioquímicos, montaña mojada, examen del histopatologia, presencia de las toxinas y técnicas manejando usaron. Simplemente el tiempo del cultivo inconstante interfirió a total que

    16. Changing character: A narrative review of personality change in psychotherapies for personality disorder.

      Science.gov (United States)

      Keefe, John R; DeRubeis, Robert J

      2018-01-19

      Personality disorder (PD) is a negative prognostic indicator for treatment, and absolute improvements in functioning among these patients are often modest. This may be because personality features that give rise to dysfunction in PD are not targeted optimally during most treatments. Attachment, mentalization, core beliefs, and personality organization/defense use were identified as personality constructs that have been pursued in treatment studies and that are proposed to underlie PD. All constructs correlate with psychiatric symptoms, PD diagnosis, and functioning. Defense mechanisms and core beliefs further distinguish specific PDs, whereas personality organization separates more versus less severe PDs. Evidence from treatment and naturalistic studies indicate that maturation of defense mechanisms temporally precedes improvements in symptoms and functioning. Changes in attachment and mentalization correlate with some outcomes, but mediation of improvement has not been established. In psychodynamic therapy, transference interpretations may promote amelioration of personality dysfunction. With the exception of attachment, the experimental literature is lacking that could explicate the mechanisms by which these personality constructs maintain psychosocial dysfunction. Future research should aim to identify changes in these mechanisms that mediate positive outcomes in PD, as well as the specific therapeutic procedures that best promote positive change in PD.

    17. ERP responses to person names as a measure of trait inference in person perception.

      Science.gov (United States)

      Wang, Lin; Bastiaansen, Marcel; Yang, Yufang

      2015-01-01

      Using event-related potentials (ERPs), this study examines how trait information inferred from behaviors is associated with person names. In linguistic discourses, person names were associated with descriptions of either positive or negative behaviors. In a subsequent explicit evaluation task, the previously described person names were presented in isolation, and the participants were asked to judge the emotional valence of these names. We found that the names associated with positive descriptions elicited a larger positivity in the ERP than the names associated with negative descriptions. The results indicate that the emotional valence of person names attached to person perception can be dynamically influenced by short descriptions of the target person, probably due to trait inference based on the provided behavioral descriptions.

    18. Personal strategic planning

      Directory of Open Access Journals (Sweden)

      Rolando Juan Soliz Estrada

      2011-01-01

      Full Text Available Reconciling personal skills with the demands of a globalized and competitive market has become a pre-requisite for professionals aspiring for success in their careers. The quest for personal fulfillment has encouraged people to search for tools which develop their talents and balance their efforts, in order to achieve a better, happier and healthier life. As an option, planning, which historically was restricted to being an organizational tool, today has also come to be used by individuals who desire personal success. In this way, the objective of this article is to develop a model of Personal Strategic Planning which takes into account the various operation areas and human performance. The proposed model is divided into: Individual Planning, Professional Planning, Family Planning, Personal Business Planning and Political Participation, Social and Religious/Spiritual Planning and their respective fields. In order to analyse and validate the model, exploratory research of a qualitative nature was used through primary and secondary data sources. From the results obtained by the model, it is possible to consider their importance to future research, once the studied areas can be developed in subsequent works.

    19. Personality and recovery: integrating personality assessment data to facilitate the recovery process.

      Science.gov (United States)

      Donat, D C

      2001-01-01

      The relatively enduring and persistent nature of personality traits means that they will likely continue to impact the course of psychiatric recovery after Axis I symptoms are stabilized. These traits can significantly impact the choices that recovering persons make and the quality of interpersonal relationships with care providers who are trying to facilitate the recovery process. Despite this, they are often inadequately assessed and considered in providing psychiatric care. This manuscript reviews the common combinations of personality traits that have emerged across a variety of clinical samples. The implications of these personality features for the provision of care in an inpatient setting to facilitate recovery are discussed.

    20. Nikolai Berdyaev’s Personalism

      Directory of Open Access Journals (Sweden)

      Richard A. Hughes

      2015-10-01

      Full Text Available The author portrays Russian philosopher Nikolai Berdyaev as a pioneer in Eastern Orthodox theology with his ideas of freedom and personality. After his deportation from the Soviet Union in 1922, Berdyaev expounded persona-lism in opposition to Western individualism and Marxist collecti-vism. Personality exists in the image and likeness of God, and it culminates in deification. He drew upon the Sobornost’ tradition of Russia and interpreted personality as a communion of love in contrast to reflective self-consciousness of the Augustinian tradition of Western theology.

    1. Personal Branding Through Fashion Blogging

      Directory of Open Access Journals (Sweden)

      Yuanita Safitri

      2017-01-01

      Full Text Available The objective of this research was to analyze personal branding development from personal brand identity, personal brand positioning, and personal brand assessment. The object of this research was Diana Rikasari's blog “Hot Chocolate and Mint”. She is one of prominent influence and fashion blogger from Indonesia. The research used the qualitative method with data collection by virtual observation from June until August 2016. Rikasari’s personal branding showed on her blog was the fashionably smart woman who had entrepreneurship competence. This research finds out that Diana Rikasari success to make her personal identity by her blog profile and blog posting. Her positioning is clear as Indonesian modern woman. The personal brand assessment can be seen through the achievements and feedbacks on her blog post, both positive or negative.

    2. Personality and persona: personality processes in self-presentation.

      Science.gov (United States)

      Leary, Mark R; Allen, Ashley Batts

      2011-12-01

      This article examines the role that personality variables and processes play in people's efforts to manage their public images. Although most research on self-presentation has focused on situational influences, people differ greatly in the degree to which they care about others' impressions of them, the types of impressions they try to convey, and their evaluations of their self-presentational effectiveness. Personality constructs such as public self-consciousness, approval motivation, and fear of negative evaluation are associated with the motive to manage one's impressions, and people who differ in self-disclosure and desire for privacy differentially reveal information about themselves to others. Other variables relating to people's self-concepts, interpersonal goals, and traits influence the construction of specific images. Finally, the extent to which people believe they are capable of making desired impressions influences their impression management strategies and how they respond to other people's evaluations. © 2010 The Authors. Journal of Personality © 2011, Wiley Periodicals, Inc.

    3. Benchmarking wide swath altimetry-based river discharge estimation algorithms for the Ganges river system

      Science.gov (United States)

      Bonnema, Matthew G.; Sikder, Safat; Hossain, Faisal; Durand, Michael; Gleason, Colin J.; Bjerklie, David M.

      2016-04-01

      The objective of this study is to compare the effectiveness of three algorithms that estimate discharge from remotely sensed observables (river width, water surface height, and water surface slope) in anticipation of the forthcoming NASA/CNES Surface Water and Ocean Topography (SWOT) mission. SWOT promises to provide these measurements simultaneously, and the river discharge algorithms included here are designed to work with these data. Two algorithms were built around Manning's equation, the Metropolis Manning (MetroMan) method, and the Mean Flow and Geomorphology (MFG) method, and one approach uses hydraulic geometry to estimate discharge, the at-many-stations hydraulic geometry (AMHG) method. A well-calibrated and ground-truthed hydrodynamic model of the Ganges river system (HEC-RAS) was used as reference for three rivers from the Ganges River Delta: the main stem of Ganges, the Arial-Khan, and the Mohananda Rivers. The high seasonal variability of these rivers due to the Monsoon presented a unique opportunity to thoroughly assess the discharge algorithms in light of typical monsoon regime rivers. It was found that the MFG method provides the most accurate discharge estimations in most cases, with an average relative root-mean-squared error (RRMSE) across all three reaches of 35.5%. It is followed closely by the Metropolis Manning algorithm, with an average RRMSE of 51.5%. However, the MFG method's reliance on knowledge of prior river discharge limits its application on ungauged rivers. In terms of input data requirement at ungauged regions with no prior records, the Metropolis Manning algorithm provides a more practical alternative over a region that is lacking in historical observations as the algorithm requires less ancillary data. The AMHG algorithm, while requiring the least prior river data, provided the least accurate discharge measurements with an average wet and dry season RRMSE of 79.8% and 119.1%, respectively, across all rivers studied. This poor

    4. Divided versus selective attention: evidence for common processing mechanisms.

      Science.gov (United States)

      Hahn, Britta; Wolkenberg, Frank A; Ross, Thomas J; Myers, Carol S; Heishman, Stephen J; Stein, Dan J; Kurup, Pradeep K; Stein, Elliot A

      2008-06-18

      The current study revisited the question of whether there are brain mechanisms specific to divided attention that differ from those used in selective attention. Increased neuronal activity required to simultaneously process two stimulus dimensions as compared with each separate dimension has often been observed, but rarely has activity induced by a divided attention condition exceeded the sum of activity induced by the component tasks. Healthy participants performed a selective-divided attention paradigm while undergoing functional Magnetic Resonance Imaging (fMRI). The task required participants to make a same-different judgment about either one of two simultaneously presented stimulus dimensions, or about both dimensions. Performance accuracy was equated between tasks by dynamically adjusting the stimulus display time. Blood Oxygenation Level Dependent (BOLD) signal differences between tasks were identified by whole-brain voxel-wise comparisons and by region-specific analyses of all areas modulated by the divided attention task (DIV). No region displayed greater activation or deactivation by DIV than the sum of signal change by the two selective attention tasks. Instead, regional activity followed the tasks' processing demands as reflected by reaction time. Only a left cerebellar region displayed a correlation between participants' BOLD signal intensity and reaction time that was selective for DIV. The correlation was positive, reflecting slower responding with greater activation. Overall, the findings do not support the existence of functional brain activity specific to DIV. Increased activity appears to reflect additional processing demands by introducing a secondary task, but those demands do not appear to qualitatively differ from processes of selective attention.

    5. Identifying person-fit latent classes, and explanation of categorical and continuous person misfit

      NARCIS (Netherlands)

      Conijn, J.M.; Sijtsma, K.; Emons, W.H.M.

      2016-01-01

      Latent class (LC) cluster analysis of a set of subscale lz person-fit statistics was proposed to explain person misfit on multiscale measures. The proposed explanatory LC person-fit analysis was used to analyze data of students (N = 91,648) on the nine-subscale School Attitude Questionnaire Internet

    6. John locke on personal identity.

      Science.gov (United States)

      Nimbalkar, Namita

      2011-01-01

      John Locke speaks of personal identity and survival of consciousness after death. A criterion of personal identity through time is given. Such a criterion specifies, insofar as that is possible, the necessary and sufficient conditions for the survival of persons. John Locke holds that personal identity is a matter of psychological continuity. He considered personal identity (or the self) to be founded on consciousness (viz. memory), and not on the substance of either the soul or the body.

    7. John Locke on Personal Identity**

      OpenAIRE

      Nimbalkar, Namita

      2011-01-01

      John Locke speaks of personal identity and survival of consciousness after death. A criterion of personal identity through time is given. Such a criterion specifies, insofar as that is possible, the necessary and sufficient conditions for the survival of persons. John Locke holds that personal identity is a matter of psychological continuity. He considered personal identity (or the self) to be founded on consciousness (viz. memory), and not on the substance of either the soul or the body.

    8. Language-based communication strategies that support person-centered communication with persons with dementia.

      Science.gov (United States)

      Savundranayagam, Marie Y; Moore-Nielsen, Kelsey

      2015-10-01

      There are many recommended language-based strategies for effective communication with persons with dementia. What is unknown is whether effective language-based strategies are also person centered. Accordingly, the objective of this study was to examine whether language-based strategies for effective communication with persons with dementia overlapped with the following indicators of person-centered communication: recognition, negotiation, facilitation, and validation. Conversations (N = 46) between staff-resident dyads were audio-recorded during routine care tasks over 12 weeks. Staff utterances were coded twice, using language-based and person-centered categories. There were 21 language-based categories and 4 person-centered categories. There were 5,800 utterances transcribed: 2,409 without indicators, 1,699 coded as language or person centered, and 1,692 overlapping utterances. For recognition, 26% of utterances were greetings, 21% were affirmations, 13% were questions (yes/no and open-ended), and 15% involved rephrasing. Questions (yes/no, choice, and open-ended) comprised 74% of utterances that were coded as negotiation. A similar pattern was observed for utterances coded as facilitation where 51% of utterances coded as facilitation were yes/no questions, open-ended questions, and choice questions. However, 21% of facilitative utterances were affirmations and 13% involved rephrasing. Finally, 89% of utterances coded as validation were affirmations. The findings identify specific language-based strategies that support person-centered communication. However, between 1 and 4, out of a possible 21 language-based strategies, overlapped with at least 10% of utterances coded as each person-centered indicator. This finding suggests that staff need training to use more diverse language strategies that support personhood of residents with dementia.

    9. Personalized physiological medicine

      NARCIS (Netherlands)

      Ince, Can

      2017-01-01

      This paper introduces the concept of personalized physiological medicine that is specifically directed at the needs of the critically ill patient. This differs from the conventional view of personalized medicine, characterized by biomarkers and gene profiling, instead focusing on time-variant

    10. Personal Usability Constructs

      DEFF Research Database (Denmark)

      Hertzum, Morten; Clemmensen, Torkil; Hornbæk, Kasper

      2011-01-01

      Whereas the concept of usability is predominantly defined analytically, people relate to systems through personal usability constructs. Based on 48 repertory-grid interviews, this study investigates how such personal constructs are affected by two factors crucial to the international development...

    11. Translating chimpanzee personality to humans: Investigating the transportability of chimpanzee-derived personality scales to humans.

      Science.gov (United States)

      Latzman, Robert D; Sauvigné, Katheryn C; Hopkins, William D

      2016-06-01

      There is a growing interest in the study of personality in chimpanzees with repeated findings of a similar structure of personality in apes to that found in humans. To date, however, the direct translational value of instruments used to assess chimpanzee personality to humans has yet to be explicitly tested. As such, in the current study we sought to determine the transportability of factor analytically-derived chimpanzee personality scales to humans in a large human sample (N = 301). Human informants reporting on target individuals they knew well completed chimpanzee-derived and human-derived measures of personality from the two most widely studied models of human personality: Big Five and Big Three. The correspondence between informant-reported chimpanzee- and human-derived personality scales was then investigated. Results indicated high convergence for corresponding scales across most chimpanzee- and human-derived personality scales. Findings from the current study provide evidence that chimpanzee-derived scales translate well to humans and operate quite similarly to the established human-derived personality scales in a human sample. This evidence of transportability lends support to the translational nature of chimpanzee personality research suggesting clear relevance of this growing literature to humans. Am. J. Primatol. 78:601-609, 2016. © 2015 Wiley Periodicals, Inc. © 2015 Wiley Periodicals, Inc.

    12. Investigating the prevalence of personality disorders and its relationship with personality traits among students

      OpenAIRE

      Davod Ghaderi; Ali Mostafaei; Saadi Bayazidi; Mahdi Shahnazari

      2016-01-01

      The present study was aimed to investigate the prevalence of personality disorders and its relationship with personality traits among students. This research was among epidemiological-correlational descriptive studies. Method: For this purpose, 389 male students were selected via a multi-stage cluster sampling method. All subjects completed Millon's personality disorder (1987) and five-factor personality Costaand McCrae's questionnaires (1989). Results: The results showed that the prevalence ...

    13. 1 1 2 3 Effect of basalt, silica sand and fly ash on the mechanical ...

      Indian Academy of Sciences (India)

      21

      The purpose of this paper is to manufacture quaternary polymer concretes and ... Keywords: Polymer concrete, Mechanical strength, Mixture design, Fly ash, Silica .... The silica foundry sand used was 101TM from the Silica Sand MFG .... To reduce the production cost of PCs, it is necessary to minimize the epoxy content in.

    14. 77 FR 52325 - Certain New Chemicals; Receipt and Status Information

      Science.gov (United States)

      2012-08-29

      ...'' system, which means EPA will not know your identity or contact information unless you provide it in the... number). ii. Follow directions. The Agency may ask you to respond to specific questions or organize... dust, Mfg., Inc. component to automotive achieve desired metal recovery. zinc content. P-12-0483 08/01...

    15. Personal Competencies/Personalized Learning: Reflection on Instruction. A Peer-to-Peer Learning and Observation Tool

      Science.gov (United States)

      Twyman, Janet; Redding, Sam

      2015-01-01

      This publication and its companion, "Personal Competencies/Personalized Learning: Lesson Plan Reflection Guide," were created in response to a request for further development of the practical application of personalized learning concepts by teachers. Personalized learning varies the time, place, and pace of learning for each student, and…

    16. Comentario Académico Efraim Otero Ruiz

      Directory of Open Access Journals (Sweden)

      Efraim Otero Ruiz

      1996-11-01

      Full Text Available <div>Con la insistencia que le es característica, el Académico José Félix Patiño nos reitera, o mejor, nos repica una vez más, en esta Academia, sobre la importancia de lo que él llama el nuevo paradigma, el de la informática, en la formación y el desempeño del médico contemporáneo. Creo que se me ha escogido a mí para ser su comentarista por haber sido la única persona que, en el curso de 15 años, lo ha acompañado solidariamente (aunque a veces nos separen distancias físicas y hasta profesionales verdaderamente anchurosas en lo esencial de esta idea, desde cuando fundamos, en 1981, el programa «FEPAFEM-COLCIENCIAS-OFA» de Informática Biomédica que desde entonces recibió el nombre de INFORMED.div>> div>>El fue el primero, quizás el único, que captó, en un momento determinado, las perspectivas que abría a la enseñanza y a la investigación médicas el primer programa de computador «en línea», abierto por la National Library of Medicine de los Estados Unidos (llamado desde entonces MEDLARSMEDLINE y lo que podría lograr de él Colombia y Latinoamérica, dadas incluso nuestras precarias comunicaciones y la inexistencia, por entonces entre nosotros, de los computadores personales. A esa visión pionera y a esa persistencia en una idea realizada fructíferamente, debe rendírsele reconocimiento, admiración y homenaje.div>> div>>Thomas Kuhn, en su libro «La estructura de las revoluciones científicas»! ha dicho que éstas se cumplen, justamente, mediante el establecimiento de nuevos paradigmas que reemplazan a otros ya decadentes u obsoletos. Si miramos la historia de las comunicaciones a través de la evolución de la humanidad, vemos que el primer paradigma se establece con la aparición del lenguaje escrito, quizás en el momento que surgen las tabletas de barro y el cunciforme de las culturas mesopotámicas; pero por su misma dificultad tecnológica, por ser una artesanía (que alcanza su

    17. Brand Personality Creation through Advertising

      OpenAIRE

      Ouwersloot Hans; Tudorica Anamaria

      2001-01-01

      Brand Personality is one of the core dimensions of brand equity. Brand personality refers to the emotional side of a brand image. It is created by all experiences of consumers with a brand, but advertising plays a dominant role in personality creation. In this paper we explore the mechanism that builds brand personality with the help of advertising. We integrate advertising models with the theory of brand personality. Our integrated framework leads to a number of propositions that set an agen...

    18. The Stigma of Personality Disorders.

      Science.gov (United States)

      Sheehan, Lindsay; Nieweglowski, Katherine; Corrigan, Patrick

      2016-01-01

      This article reviews the recent literature on the stigma of personality disorders, including an overview of general mental illness stigma and an examination of the personality-specific stigma. Overall, public knowledge of personality disorders is low, and people with personality disorders may be perceived as purposefully misbehaving rather than experiencing an illness. Health provider stigma seems particularly pernicious for those with borderline personality disorder. Most stigma research on personality disorders has been completed outside the USA, and few stigma-change interventions specific to personality disorder have been scientifically tested. Limited evidence suggests that health provider training can improve stigmatizing attitudes and that interventions combining positive messages of recovery potential with biological etiology will be most impactful to reduce stigma. Anti-stigma interventions designed specifically for health providers, family members, criminal justice personnel, and law enforcement seem particularly beneficial, given these sources of stigma.

    19. Instincts and personality

      NARCIS (Netherlands)

      De Raad, B.; Doddema-Winsemius, M

      In this study we investigate the usefulness of the instinct-conception for personality trait-research. Of particular interest is the effectiveness-connotation of instincts for personality conceptualizations. In its kind, the study forms an indirect test of the so-called psycholexical approach and

    20. Personal literary interpretation

      Directory of Open Access Journals (Sweden)

      Michał Januszkiewicz

      2015-11-01

      Full Text Available The article titled “Personal literary interpretation” deals with problems which have usually been marginalized in literary studies, but which seem to be very important in the context of the humanities, as broadly defined. The author of this article intends to rethink the problem of literary studies not in objective, but in personal terms. This is why the author wants to talk about what he calls personal literary interpretation, which has nothing to do with subjective or irrational thinking, but which is rather grounded in the hermeneutical rule that says that one must believe in order tounderstand a text or the other (where ‘believe’ also means: ‘to love’, ‘engage’, and ‘be open’. The article presents different determinants of this attitude, ranging from Dilthey to Heidegger and Gadamer. Finally, the author subscribes to the theory of personal interpretation, which is always dialogical.

    1. Moral Personality Growth

      Directory of Open Access Journals (Sweden)

      Jana Kalin

      1998-12-01

      Full Text Available Learning in terms of personality growth is a life-long process, just as personality growth itself is a life-long process. Kalin presents a number of psychological theories and their impact on moral development - which is an integral part of personality growth. The paper further treats the formation and changing of beliefs, and the role of education in the two processes. Great emphasis is put on cognitive theories; Kalin explains those formulated by L. Kohlberg and J. Rest. In discussing the process of shaping and changing one's views, special emphasis is put on the environment, or rather the social group an individual belongs to, and on the influence of personality traits and experience. The paper juxtaposes the influence - strengths and weaknesses - of the psychology of persuasion and education on forming and changing one's views, taken into consideration that views consist of cognitive, emotive and conative dimensions.

    2. Modeling borderline personality disorder based on the neurobehavioral foundation of major personality traits.

      Science.gov (United States)

      Depue, Richard A; Fu, Yu

      2012-03-01

      Borderline personality disorder (BPD) is an exceedingly complex behavioral phenomenon that is in need of conceptual clarification within a larger model of personality disorders (PDs). The association of personality traits to BPD is discussed initially as a means of introducing a dimensional personality approach to understanding BPD. While this model suggests that PDs emerge at the extremes of personality dimensions, attempts to demonstrate such an association have been empirically disappointing and conceptually unilluminating. Therefore, in this article, we attempt to extend such models by outlining the neurobehavioral systems that underlie major personality traits, and highlight the evidence that they are subject to experience-dependent modification that can be enduring through effects on genetic expression, mainly through processes known as epigenetics. It is through such processes that risk for personality disorder may be modified by experience at any point in development, but perhaps especially during early critical periods of development. We conclude by presenting a multidimensional model of PDs, in general, and BPD, in particular, that relies on the concepts developed earlier in the article. Our goal is to provide a guide for novel clinical conceptualization and assessment of PDs, as well as research on their psychobiological nature and pharmacological treatment.

    3. Violence and Violence Research in Africa South of the Sahara

      Directory of Open Access Journals (Sweden)

      Suren Pillay

      2011-07-01

      Full Text Available <div>This review presents the major lines of investigation regarding violence in Africa since the Cold War. After a historical introduction to the development of violent phenomena and their political contexts, diverse issues such as civil war, democratization, vigilantism, and the role of youth are assessed. It is argued that recent research has produced important insights by re-focusing on violent phenomena beyond the state. Yet despite the increasing number of non-state violent actors active on the African continent, to speak of a “privatization” of violence may be premature.div>

    4. Searching for the Prosocial Personality: A Big Five Approach to Linking Personality and Prosocial Behavior.

      Science.gov (United States)

      Habashi, Meara M; Graziano, William G; Hoover, Ann E

      2016-09-01

      The search for the prosocial personality has been long and controversial. The current research explores the general patterns underlying prosocial decisions, linking personality, emotion, and overt prosocial behavior. Using a multimethod approach, we explored the links between the Big Five dimensions of personality and prosocial responding. Across three studies, we found that agreeableness was the dimension of personality most closely associated with emotional reactions to victims in need of help, and subsequent decisions to help those individuals. Results suggest that prosocial processes, including emotions, cognitions, and behaviors, may be part of a more general motivational process linked to personality. © 2016 by the Society for Personality and Social Psychology, Inc.

    5. Personalized medicine in psychiatry

      DEFF Research Database (Denmark)

      Wium-Andersen, Ida Kim; Vinberg, Maj; Kessing, Lars Vedel

      2017-01-01

      Background: Personalized medicine is a model in which a patient’s unique clinical, genetic, and environmental characteristics are the basis for treatment and prevention.  Aim, method, and results: This review aims to describe the current tools, phenomenological features, clinical risk factors......, and biomarkers used to provide personalized medicine. Furthermore, this study describes the target areas in which they can be applied including diagnostics, treatment selection and response, assessment of risk of side-effects, and prevention.  Discussion and conclusion: Personalized medicine in psychiatry....... The discussion proposes possible solutions to narrow this gap and to move psychiatric research forward towards personalized medicine....

    6. Motivational Basis of Personality Traits: A Meta-Analysis of Value-Personality Correlations.

      Science.gov (United States)

      Fischer, Ronald; Boer, Diana

      2015-10-01

      We investigated the relationships between personality traits and basic value dimensions. Furthermore, we developed novel country-level hypotheses predicting that contextual threat moderates value-personality trait relationships. We conducted a three-level v-known meta-analysis of correlations between Big Five traits and Schwartz's (1992) 10 values involving 9,935 participants from 14 countries. Variations in contextual threat (measured as resource threat, ecological threat, and restrictive social institutions) were used as country-level moderator variables. We found systematic relationships between Big Five traits and human values that varied across contexts. Overall, correlations between Openness traits and the Conservation value dimension and Agreeableness traits and the Transcendence value dimension were strongest across all samples. Correlations between values and all personality traits (except Extraversion) were weaker in contexts with greater financial, ecological, and social threats. In contrast, stronger personality-value links are typically found in contexts with low financial and ecological threats and more democratic institutions and permissive social context. These effects explained on average more than 10% of the variability in value-personality correlations. Our results provide strong support for systematic linkages between personality and broad value dimensions, but they also point out that these relations are shaped by contextual factors. © 2014 Wiley Periodicals, Inc.

    7. Personalized medicine in dentistry

      Directory of Open Access Journals (Sweden)

      Pushpa S Pudakalkatti

      2017-01-01

      Full Text Available Personalized medicine is a branch of medicine that proposes customization of healthcare in which decisions and treatment are tailored according to individual patient needs. The field of personalized medicine relies on genetic information, proteomic information and clinical patient characteristics to individualize treatment. With advances in genetics, proteomics, pharmacogenetics and knowledgeable patient population, the opportunity exists to deliver never before levels of personalized care. Although general dentists may consider personalized medicine a concept for the future, the reality is that its direct application to everyday dentistry is closer than one might think. Use of personalized medicine in dentistry, especially in periodontology is progressing rapidly, and dentist should consider this approach while treating patients. Google and PubMed search was done to select articles for present review. Total 17 articles were used to compile information.

    8. An Empirically Derived Taxonomy for Personality Diagnosis: Bridging Science and Practice in Conceptualizing Personality

      Science.gov (United States)

      Westen, Drew; Shedler, Jonathan; Bradley, Bekh; DeFife, Jared A.

      2013-01-01

      Objective The authors describe a system for diagnosing personality pathology that is empirically derived, clinically relevant, and practical for day-to-day use. Method A random national sample of psychiatrists and clinical psychologists (N=1,201) described a randomly selected current patient with any degree of personality dysfunction (from minimal to severe) using the descriptors in the Shedler-Westen Assessment Procedure–II and completed additional research forms. Results The authors applied factor analysis to identify naturally occurring diagnostic groupings within the patient sample. The analysis yielded 10 clinically coherent personality diagnoses organized into three higher-order clusters: internalizing, externalizing, and borderline-dysregulated. The authors selected the most highly rated descriptors to construct a diagnostic prototype for each personality syndrome. In a second, independent sample, research interviewers and patients’ treating clinicians were able to diagnose the personality syndromes with high agreement and minimal comorbidity among diagnoses. Conclusions The empirically derived personality prototypes described here provide a framework for personality diagnosis that is both empirically based and clinically relevant. PMID:22193534

    9. Social skills of persons with self-defeating personality.

      Science.gov (United States)

      Schill, T

      1995-10-01

      55 undergraduate men and 55 women took Schill's 1990 Self-defeating Personality Scale and Lorr, Youniss, and Stefic's (1991) multidimensional Social Relations Survey. As expected, persons who endorsed more self-defeating characteristics scored lower on scales which make up the Social Skills or Assertiveness Factor. However, these scores did not have significant correlations with the Empathy or Social Approval Need Scales; two of the three scales which make up the Empathy Factor. The results were discussed in terms of prior work relating deficits in social skills to dysfunctional early parenting.

    10. [Psychopathy and associated personality disorders: searching for a particular effect of the borderline personality disorder?].

      Science.gov (United States)

      Nioche, A; Pham, T H; Ducro, C; de Beaurepaire, C; Chudzik, L; Courtois, R; Réveillère, C

      2010-06-01

      Recent clinical and empirical works are based on Cleckley's clinical observations in which psychopathy is viewed as a personality disorder, characterised by a lack of emotions, callousness, unreliability and superficiality. Hare operationalised Cleckley's concept of psychopathy by developing the Psychopathy Checklist-Revised composed of 20 items that load on two factors in majority: factor 1 (personality aspects of psychopathy) and factor 2 (behavioural manifestations), close to the antisocial personality disorder (DSM-IV criteria). Comorbidity is strong with antisocial personality disorder but also with histrionic, narcissistic and borderline disorders. As results of categorical studies relative to comorbidity suggest a strong comorbidity between psychopathy and other personality disorders, and particularly cluster B disorders (axis II, DSM-IV), this study assesses the relationships between psychopathy (dimensional approach) and personality disorders (categorical approach) and particularly with the borderline personality disorder. The aim of this study is also to underline the complementarity of categorical (SCID-II) and dimensional approaches (PCL-R), and the utility of the standardised clinical examination. We hypothesised positive associations between psychopathy and other personality disorders, mainly with the cluster B axis II (narcissistic, antisocial, histrionic, and borderline). Among those disorders, a particular link exists with the borderline personality disorder, considering that their association may attenuate the pathological level of the psychopathy. The sample included 80 male inmates from French prisons (age: M=31.48; SD=11.06). Each participant was evaluated with the PCL-R to assess the level of psychopathy and the SCID-II to assess the possible presence of personality disorders. The MINI and the WAIS-III were used to exclude respectively those who presented an axis I comorbidity (mood disorders and psychotic disorders established at the moment

    11. [Personality disorders, violence and criminal behaviour].

      Science.gov (United States)

      Palmstierna, Tom

      2016-12-06

      Personality disorders, violence and criminal behaviour The importance of personality disorders for violent and criminal behaviour is illustrated by their high prevalence in prison populations. Especially antisocial personality disorder and antisocial personality traits are linked to violence. During diagnostic assessment of personality disorders, violence risk screening is recommended. Cognitive behaviour treatment focused on violent behaviour has some effect in criminal populations, but the antisocial personality traits are resistant to treatment. Evidence for pharmacological treatment of repetitive aggressive behaviour is weak. But, bensodiazepines seem to increase the risk of violent behaviour among patients with personality disorders. Antisocial personality traits diminish over time. This spontaneous decrease can be delayed by comorbidity such as other personality disorder, substance use disorder, psychosis and attention deficit disorders. Therefore it is recommended to actively treat these comorbid conditions.

    12. Personality Traits in Huntington's Disease

      DEFF Research Database (Denmark)

      Larsen, Ida Unmack; Mortensen, Erik Lykke; Vinther-Jensen, Tua

      2016-01-01

      Huntington's disease (HD) is associated with risk for developing psychiatric symptoms. Vulnerability or resilience to psychiatric symptoms may be associated with personality traits. This exploratory study, aimed to investigate personality traits in a large cohort of HD carriers and at risk gene......-expansion negative individuals (HD non-carriers), exploring whether carrying the HD gene or growing up in an HD family influences personality traits. Forty-seven HD carriers, Thirty-nine HD non-carriers, and 121 healthy controls answered the Danish version of the revised NEO personality inventory. Comparisons...... symptoms. Our findings suggest that, there is no direct effect of the HD gene on personality traits, but that personality assessment may be relevant to use when identifying individuals from HD families who are vulnerable to develop psychiatric symptoms....

    13. 19 CFR 148.42 - Personal effects.

      Science.gov (United States)

      2010-04-01

      ... 19 Customs Duties 2 2010-04-01 2010-04-01 false Personal effects. 148.42 Section 148.42 Customs... (CONTINUED) PERSONAL DECLARATIONS AND EXEMPTIONS Exemptions for Nonresidents § 148.42 Personal effects. (a... adornment, toilet articles, and similar personal effects. “Similar personal effects” include all articles...

    14. Dimensions of normal and abnormal personality: Elucidating DSM-IV personality disorder symptoms in adolescents

      NARCIS (Netherlands)

      Tromp, N.B.; Koot, H.M.

      2010-01-01

      The present study aimed to elucidate dimensions of normal and abnormal personality underlying DSM-IV personality disorder (PD) symptoms in 168 adolescents referred to mental health services. Dimensions derived from the Big Five of normal personality and from Livesley's (2006) conceptualization of

    15. Semantic Learning Service Personalized

      Directory of Open Access Journals (Sweden)

      Yibo Chen

      2012-02-01

      Full Text Available To provide users with more suitable and personalized service, personalization is widely used in various fields. Current e-Learning systems search for learning resources using information search technology, based on the keywords that selected or inputted by the user. Due to lack of semantic analysis for keywords and exploring the user contexts, the system cannot provide a good learning experiment. In this paper, we defined the concept and characteristic of the personalized learning service, and proposed a semantic learning service personalized framework. Moreover, we made full use of semantic technology, using ontologies to represent the learning contents and user profile, mining and utilizing the friendship and membership of the social relationship to construct the user social relationship profile, and improved the collaboration filtering algorithm to recommend personalized learning resources for users. The results of the empirical evaluation show that the approach is effectiveness in augmenting recommendation.

    16. Keratoconus and Personality-A Review.

      Science.gov (United States)

      Mannis, Mark J; Ling, Jennifer J; Kyrillos, Ralph; Barnett, Melissa

      2018-03-01

      To assess the existing literature on the subject of keratoconus and personality and to propose a theory that might account for the perceived personality changes associated with this condition. A literature search was conducted in the PubMed database using the term "keratoconus" in combination with keywords such as personality, psychiatry, psychology, anxiety, depression, or psychosis. A total of 15 articles pertaining to personality and psychiatric disorders in keratoconus were retained and reviewed. Although patients with keratoconus tend to score differently on personality scales compared with normal controls, the literature fails to substantiate the existence of a unique "keratoconic personality." Instead, patients with keratoconus prove to have more dysfunctional coping mechanisms that specifically alter their interaction with health care providers and may account for the persistent clinical impression of less respectful, conforming, and cooperative patients. We hypothesize that the stage of life at which keratoconus commonly presents plays a crucial role in personality and coping mechanism development that significantly affects behavioral patterns and the relationship with caregivers.

    17. Personality functioning in patients with avoidant personality disorder and social phobia

      NARCIS (Netherlands)

      Eikenaes, I.; Hummelen, B.; Abrahamsen, G.; Andrea, H.; Wilberg, T.

      2013-01-01

      Avoidant personality disorder (APD) and social phobia (SP) are closely related, such that they are suggested to represent different severity levels of one social anxiety disorder. This cross-sectional study aimed to compare patients with APD to patients with SP, with particular focus on personality

    18. Severity of personality disorders and domains of general personality dysfunction related to attachment.

      Science.gov (United States)

      Hengartner, Michael P; von Wyl, Agnes; Tanis, Thachell; Halmi, Winter; Galynker, Igor; Cohen, Lisa J

      2015-08-01

      This is the first study to link attachment to both severity of total DSM-IV personality disorder (PD) traits and domains of general personality dysfunction, using a sample of 72 inpatients from New York City. We assessed a measure of global PD severity and the core domains of personality functioning using the severity indices of personality problems (SIPP-118). Attachment was measured with the experience in close relationships-revised (ECR-R) and the relationship style questionnaire (RSQ). Global PD severity correlated most strongly with attachment anxiety (r = 0.65). Regression of the SIPP-118 domains on attachment produced models that accounted for a substantial proportion of variance in those scales (R(2) ranging from 28.2 to 54.2%). SIPP-118 relational capacities were the strongest predictor of ECR-R avoidance (β = -0.88) and anxiety (β = -0.58), as well as RSQ secure (β = 0.53) and fearful (β = -0.65). In conclusion, insecure attachment strongly related to the severity of global PD traits and specifically to relational capacities, which are a higher-order domain of general personality dysfunction. These findings provide further evidence that interpersonal problems are at the core of PDs and that attachment could constitute an important mediator of the social dysfunction in persons with personality pathology. Copyright © 2015 John Wiley & Sons, Ltd.

    19. Employee attitudes towards aggression in persons with dementia: Readiness for wider adoption of person-centered frameworks.

      Science.gov (United States)

      Burshnic, V L; Douglas, N F; Barker, R M

      2018-04-01

      Person-centered care, as compared to standard approaches, is a widely accepted, evidence-based approach for managing aggressive behaviour in persons with dementia. The attitudes, beliefs and values of long-term care and mental health nursing employees are important prerequisites to implementing person-centered practices. Research shows that nursing employees typically support person-centered approaches; however, less is known about the attitudes of non-nursing employee groups. Nurse managers and administrators tended to agree with person-centered approaches for managing aggression in dementia, suggesting some prerequisites are in place to support wider adoption of person-centered frameworks. Employees with more resident contact tended to support person-centered approaches the least, suggesting discipline-specific trainings may not be adequate for preparing frontline staff to use person-centered techniques. Attitudes towards aggressive behaviour may be especially varied and contradictory within certain employee groups, providing implications for facility-wide initiatives. Person-centered values and practices should be monitored and reinforced across the organization. Person-centered trainings should be interdisciplinary in nature and focused on care areas, such as mealtime or bathing. Long-term care facilities should consider allowing nurse management and registered nurses to share the burden of direct resident care with frontline employees on a more regular basis. Introduction Implementing person-centered care requires shared attitudes, beliefs and values among all care employees. Existing research has failed to examine the attitudes of non-nursing employees. Aim This study examined attitudes towards aggression among nursing and non-nursing employees to address gaps in existing research and assess readiness for wider adoption of person-centered frameworks. Method The Management of Aggression in People with Dementia Attitude Questionnaire was used to survey

    20. Personal Inquiry Manager

      NARCIS (Netherlands)

      Suarez, Angel; Ternier, Stefaan; Specht, Marcus

      2014-01-01

      The Personal Inquiry Manager (PIM) is an integration approach based on a mobile application, based on Android, to support the IBL process and gives users mobile access to their inquiries. Moreover it facilitates a more self-directed approach as it enables to set up their own personal inquiries. The

    1. Normal personality, personality disorder and psychosis: current views and future perspectives.

      Science.gov (United States)

      Balaratnasingam, Sivasankaran; Janca, Aleksandar

      2015-01-01

      The purpose of this article is to review recent literature examining the occurrence of psychotic experiences in normal population and those with personality disorders. Up to 15% of individuals in the general population report some type or degree of psychotic experience. Most of these individuals function adequately, do not require psychiatric treatment and do not receive diagnosis of a psychotic illness. A significant number of individuals diagnosed with borderline personality disorder (25-50%) also report psychotic symptoms. These are not easily differentiated from the psychotic symptoms reported by individuals with schizophrenia, nor are they always transient. However, emerging research has confirmed that individuals with schizotypal personality disorder are dimensionally related to those with schizophrenia and are at an increased risk of transition to psychosis. Psychotic symptoms are best considered as 'trans-diagnostic' entities on a continuum from normal to pathological. There is a large body of evidence for a dimensional relationship between schizotypal personality disorder and schizophrenia. There is also a significant amount of research showing that psychotic symptoms in borderline personality disorder are frequent, nontransient and represent a marker of illness severity. This review highlights the need to move beyond traditional assumptions and categorical boundaries when evaluating psychotic experiences and psychopathological phenomena.

    2. Weakly coupled mean-field game systems

      KAUST Repository

      Gomes, Diogo A.

      2016-07-14

      Here, we prove the existence of solutions to first-order mean-field games (MFGs) arising in optimal switching. First, we use the penalization method to construct approximate solutions. Then, we prove uniform estimates for the penalized problem. Finally, by a limiting procedure, we obtain solutions to the MFG problem. © 2016 Elsevier Ltd

    3. Prediction of Long Term Degradation of Insulating Materials

      Science.gov (United States)

      2015-05-01

      Mfg. Process XPA Polystyrene foam trans-1,3,3,3-Tetrafluoroprop-1-ene blowing agent Extruded XPB Polystyrene foam 1-Chloro-1,1- difluoroethane and...Honeywell 2014); the other used a combination of 1-Chloro-1,1- difluoroethane and 1,1,1,2-Tetrafluoroethane (Dow 2011). Figure 2-5(c) shows the sample

    4. Conservation laws arising in the study of forward-forward Mean-Field Games

      KAUST Repository

      Gomes, Diogo A.; Nurbekyan, Levon; Sedjro, Marc

      2017-01-01

      We consider forward-forward Mean Field Game (MFG) models that arise in numerical approximations of stationary MFGs. First, we establish a link between these models and a class of hyperbolic conservation laws as well as certain nonlinear wave equations. Second, we investigate existence and long-time behavior of solutions for such models.

    5. Conservation laws arising in the study of forward-forward Mean-Field Games

      KAUST Repository

      Gomes, Diogo A.

      2017-04-24

      We consider forward-forward Mean Field Game (MFG) models that arise in numerical approximations of stationary MFGs. First, we establish a link between these models and a class of hyperbolic conservation laws as well as certain nonlinear wave equations. Second, we investigate existence and long-time behavior of solutions for such models.

    6. Personality traits predict perceived health-related quality of life in persons with multiple sclerosis.

      Science.gov (United States)

      Zarbo, Ignazio Roberto; Minacapelli, Eleonora; Falautano, Monica; Demontis, Silvia; Carpentras, Giovanni; Pugliatti, Maura

      2016-04-01

      Personality traits can affect health-related quality of life (HRQoL) in different disorders. In multiple sclerosis (MS), personality traits can determine patients' willingness to take on more risky treatment options, predispose to neuropsychiatric symptoms and affect coping strategies. We investigated the role of personality traits as possible predictors of HRQoL in a large cohort of persons with MS (PwMS). In total, 253 consecutively recruited PwMS were screened for intellectual deficits with Raven Colour Progressive Matrices (RCPM), state anxiety with STAI-X1 and major depression on a clinical basis. PwMS' self-perceived mental and physical health status was measured with the 36-Item Short Form Health Survey (SF-36), and the personality profile with the Eysenck Personality Questionnaire (EPQ-R). The correlation between HRQoL and personality traits was investigated by means of analysis of variance, adjusting for possible confounders. Of the 253 MS patients, 195 (F:M=2.75), aged 41.7±10.2 years were included in the analysis. The variance of SF-36 mental and physical composite score was largely explained by extraversion and neuroticism. Our data confirm that PwMS' HRQoL is largely influenced by personality traits, which may therefore act as predictors of perceived quality of life and should be included in clinical and experimental settings focusing on HRQoL. © The Author(s), 2015.

    7. [Narcissistic personality disorder].

      Science.gov (United States)

      Lammers, C-H; Vater, A; Roepke, S

      2013-07-01

      Narcissism is a multifaceted term which encompasses traits of normal personality as well as a specific personality disorder. While much research has been concerned with narcissism as a trait there are only few empirical studies available on narcissistic personality disorder (NPS). The current diagnostic of NPS according to DSM-IV-TR focuses on grandiose type narcissism whereas vulnerable narcissism, which has been described by clinicians and researchers has not yet been recognised. Psychotherapy of narcissistic patients through different psychotherapeutic schools focuses mainly on processes in the therapeutic relationship, the analysis and change of grandiose and vulnerable schemas, emotion regulation techniques and correction of narcissistic behavior in favor of prosocial interactions.

    8. The DSM-5 Levels of Personality Functioning and Severity of Iranian Patients With Antisocial and Borderline Personality Disorders

      Science.gov (United States)

      Amini, Mehdi; Pourshahbaz, Abbas; Mohammadkhani, Parvaneh; Khodaie Ardakani, Mohammad Reza; Lotfi, Mozhgan

      2015-01-01

      Background: Fundamental problems with Personality Disorders (PD) diagnostic system in the previous version of DSM, led to the revision of DSM. Therefore, a multidimensional system has been proposed for diagnosis of personality disorder features in DSM-5. In the dimensional approach of DSM-5, personality disorders diagnosis is based on levels of personality functioning (Criteria A) and personality trait domains (Criteria B). Objectives: The purpose of this study was firstly, to examine the DSM-5 levels of personality functioning in antisocial and borderline personality disorders, and second, to explore which levels of personality functioning in patients with antisocial and borderline personality disorders can better predicted severity than others. Patients and Methods: This study had a cross sectional design. The participants consisted of 252 individuals with antisocial (n = 122) and borderline personality disorders (n = 130). They were recruited from Tehran prisoners, and clinical psychology and psychiatry centers of Razi and Taleghani Hospitals, Tehran, Iran. The sample was selected based on judgmental sampling. The SCID-II-PQ, SCID-II and DSM-5 levels of personality functioning were used to diagnose and assess personality disorders. The data were analyzed by correlation and multiple regression analysis. All statistical analyses were performed using the SPSS 16 software. Results: Firstly, it was found that DSM-5 levels of personality functioning have a strong correlation with antisocial and borderline personality symptoms, specially intimacy and self-directedness (P antisocial personality disorder severity (P personality disorder severity, as well (P personality functioning are a significant predictor of personality disorders severity. The results partially confirm existing studies. PMID:26430521

    9. The DSM-5 Levels of Personality Functioning and Severity of Iranian Patients With Antisocial and Borderline Personality Disorders.

      Science.gov (United States)

      Amini, Mehdi; Pourshahbaz, Abbas; Mohammadkhani, Parvaneh; Khodaie Ardakani, Mohammad Reza; Lotfi, Mozhgan

      2015-08-01

      Fundamental problems with Personality Disorders (PD) diagnostic system in the previous version of DSM, led to the revision of DSM. Therefore, a multidimensional system has been proposed for diagnosis of personality disorder features in DSM-5. In the dimensional approach of DSM-5, personality disorders diagnosis is based on levels of personality functioning (Criteria A) and personality trait domains (Criteria B). The purpose of this study was firstly, to examine the DSM-5 levels of personality functioning in antisocial and borderline personality disorders, and second, to explore which levels of personality functioning in patients with antisocial and borderline personality disorders can better predicted severity than others. This study had a cross sectional design. The participants consisted of 252 individuals with antisocial (n = 122) and borderline personality disorders (n = 130). They were recruited from Tehran prisoners, and clinical psychology and psychiatry centers of Razi and Taleghani Hospitals, Tehran, Iran. The sample was selected based on judgmental sampling. The SCID-II-PQ, SCID-II and DSM-5 levels of personality functioning were used to diagnose and assess personality disorders. The data were analyzed by correlation and multiple regression analysis. All statistical analyses were performed using the SPSS 16 software. Firstly, it was found that DSM-5 levels of personality functioning have a strong correlation with antisocial and borderline personality symptoms, specially intimacy and self-directedness (P antisocial personality disorder severity (P personality disorder severity, as well (P personality functioning are a significant predictor of personality disorders severity. The results partially confirm existing studies.

    10. Toward Privacy-Preserving Personalized Recommendation Services

      Directory of Open Access Journals (Sweden)

      Cong Wang

      2018-02-01

      Full Text Available Recommendation systems are crucially important for the delivery of personalized services to users. With personalized recommendation services, users can enjoy a variety of targeted recommendations such as movies, books, ads, restaurants, and more. In addition, personalized recommendation services have become extremely effective revenue drivers for online business. Despite the great benefits, deploying personalized recommendation services typically requires the collection of users’ personal data for processing and analytics, which undesirably makes users susceptible to serious privacy violation issues. Therefore, it is of paramount importance to develop practical privacy-preserving techniques to maintain the intelligence of personalized recommendation services while respecting user privacy. In this paper, we provide a comprehensive survey of the literature related to personalized recommendation services with privacy protection. We present the general architecture of personalized recommendation systems, the privacy issues therein, and existing works that focus on privacy-preserving personalized recommendation services. We classify the existing works according to their underlying techniques for personalized recommendation and privacy protection, and thoroughly discuss and compare their merits and demerits, especially in terms of privacy and recommendation accuracy. We also identity some future research directions. Keywords: Privacy protection, Personalized recommendation services, Targeted delivery, Collaborative filtering, Machine learning

    11. Domains and facets: hierarchical personality assessment using the revised NEO personality inventory.

      Science.gov (United States)

      Costa, P T; McCrae, R R

      1995-02-01

      Personality traits are organized hierarchically, with narrow, specific traits combining to define broad, global factors. The Revised NEO Personality Inventory (NEO-PI-R; Costa & McCrae, 1992c) assesses personality at both levels, with six specific facet scales in each of five broad domains. This article describes conceptual issues in specifying facets of a domain and reports evidence on the validity of NEO-PI-R facet scales. Facet analysis-the interpretation of a scale in terms of the specific facets with which it correlates-is illustrated using alternative measures of the five-factor model and occupational scales. Finally, the hierarchical interpretation of personality profiles is discussed. Interpretation on the domain level yields a rapid understanding of the individual interpretation of specific facet scales gives a more detailed assessment.

    12. Movement and personality development

      Directory of Open Access Journals (Sweden)

      Aida M. Aylamazyan

      2017-06-01

      Full Text Available The paper discusses the role of the movement in the process of shaping the personality, its importance as a mechanism for personality development is considered. The issue of the movement has always occupied a central place in Russian psychology. However, subsequently the movement began to be considered primarily as an executive action in human life. The role of movement in personality development can vary depending on the level it occupies in the hierarchical structure of activity, and also on the type of movement, its character, and the way it is constructed. Under certain conditions, the movement can express the attitude of the subject to the surrounding world and people. Many foreign and Russian psychologists point to a special place of the postural tonic component of the motor movement, the posture in personal regulation. The posture reflects his/her personal attitudes, the system of relationships, and, above all, the emotional attitude or emotional assessment of the current situation, the interest in the actions performed. Mastering the tonic level of motor management is based on the emotional regulation, so the ability to regulate one’s own pose is an important stage in the personality development. Posture tonic regulation of motor movements in humans reveals a qualitatively different character than in animals, this being due to the person’s facing the task of mastering his’her posture, arbitrary retention of the body in one or another position. Maintaining a vertical posture requires constant activity at an arbitrary and involuntary level of mental regulation. Mastering the posture of an unstable equilibrium presupposes the emergence of the «I» and is the last stage of the development. The way a person solves the motor task of maintaining the vertical position of the body reflects his/her specific personal strategy or attitude.

    13. Selecting Personal Computers.

      Science.gov (United States)

      Djang, Philipp A.

      1993-01-01

      Describes a Multiple Criteria Decision Analysis Approach for the selection of personal computers that combines the capabilities of Analytic Hierarchy Process and Integer Goal Programing. An example of how decision makers can use this approach to determine what kind of personal computers and how many of each type to purchase is given. (nine…

    14. Environmental factors and teenagers' personalities: The role of personal and familial Socio-Cultural Level.

      Science.gov (United States)

      Menardo, Elisa; Balboni, Giulia; Cubelli, Roberto

      2017-05-15

      Environmental (e.g., socio-cultural context), individual (e.g., genetic makeup), and interpersonal (e.g., caregiver-children relationships) factors can play a crucial role in shaping the development of the teenagers' personality. In this study, we focused on the Socio-Cultural Level that designates the set of preferences, knowledge, and behaviors that characterize an individual's way of life and depend on his or her cultural, social, and economic resources. We studied the relationship between Socio-Cultural Level (personal, maternal, and paternal) and Big Five personality traits of 191 teenagers living in the same geographical area. Results showed that Socioeconomic Status (i.e., parental education level and occupational prestige), which is the only dimension generally measured in investigations on Socio-Cultural Level, was not related with personality. In contrast, Cultural Capital and Social Capital were associated with different personality traits. Personal Cultural Capital was related to Openness to experience of boys and girls and to Extraversion of girls; personal Social Capital was related to Extraversion of girls, Emotional stability of boys, and Agreeableness of both boys and girls; maternal Cultural Capital was associated with Openness to experience of daughters. Overall, the personality of teenagers was more related to their own Cultural and Social Capital than to the Cultural and Social Capital of their parents. Moreover, the relationship between Cultural Capital and Social Capital of boys/girls and of fathers/mothers was moderate in strength. It seems that parents influence the development of personality of their teenagers indirectly, their Socio-Cultural Level shaping the Socio-Cultural Level of their sons and daughters. Copyright © 2017 Elsevier B.V. All rights reserved.

    15. Entrepreneurial personality and entrepreneurial behaviour

      OpenAIRE

      Marcela Rodica LUCA

      2017-01-01

      The paper presents a literature analysis concerning the concept of entrepreneurial personality. Several topics are discussed, such as: entrepreneurship, entrepreneurial personality, personality traits and factors associated with entrepreneurship, context variables influencing entrepreneurial behaviour, psychological explanations of entrepreneurial behaviour.

    16. Culture and first-person pronouns.

      Science.gov (United States)

      Na, Jinkyung; Choi, Incheol

      2009-11-01

      Priming research has shown that repeated exposures to first-person singular pronouns (I, my, me, mine) activate an individualistic orientation, whereas first-person plural pronouns (we, our, us, ours) activate a collectivistic orientation. However, little research has been done to explore the opposite direction of influence such that one's cultural orientation determines one's choice between first-person singular versus plural pronouns. The authors conducted three studies to examine the effects of one's cultural orientation on one's use of first-person possessive pronouns. Results show that, compared to their individualistic counterparts, participants who have a collectivistic orientation, chronically or temporarily by priming, preferred to use first-person plural possessive pronouns.

    17. State of the Art: Personalization

      DEFF Research Database (Denmark)

      Durao, Frederico Araujo; Dolog, Peter; Jahn, Karsten

      This is report surveys KIWI related work in the personalization domain. It discusses various approaches from adaptive hypermedia, user modelling, and semantic web which deal with personalization. It gives some suggestions on potential personalization strategies which can exploit knowledge...

    18. Development of naive personality perception

      OpenAIRE

      Hayashi, Tomoyuki

      2004-01-01

      Lay persons usually understand that the personality has consistency and causality. They also have the knowledge of what contents the personality consists of. Research of "theories of mind," which focuses on the developmental processes of the naive understanding of mind, suggests three stages : (a) alignment of actions (imitation) fosters the foundation of social cognition in young children (i.e., understanding that the mind causes behaviors, grasping the identity of a person, and discovering ...

    19. Personal Virtual Libraries

      Science.gov (United States)

      Pappas, Marjorie L.

      2004-01-01

      Virtual libraries are becoming more and more common. Most states have a virtual library. A growing number of public libraries have a virtual presence on the Web. Virtual libraries are a growing addition to school library media collections. The next logical step would be personal virtual libraries. A personal virtual library (PVL) is a collection…

    20. On Person Deixis

      Institute of Scientific and Technical Information of China (English)

      段翠霞

      2005-01-01

      Deixis is one of the important topics in pragmatics.Deixis can be classified into different types, but this paper only focuses on person deixis.Through the detail analysis of the usage of it we come to the conclusion that in order to understand utterances better we need to make clear the complexity of person deixis.

    1. Integrating the persons communicating

      DEFF Research Database (Denmark)

      Hermann, Jesper

      2011-01-01

      The paper presents some grounds for the working out of insights developed by Roy Harris and the fellow integrationalists, including the person-centered focus of Otto Jespersen when dealing with future communication studies. Whenever we are speaking of ‘something verbal’, immediately we are opening...... of ‘language’ evaporates, and we are left solely with persons and their understandings, actions and expressions to be investigated by us professionals, collaborating with the persons under scrutiny....

    2. Personality, personal model beliefs, and self-care in adolescents and young adults with Type 1 diabetes

      DEFF Research Database (Denmark)

      Chas Skinner, T.; Hampson, Sarah E.; Fife-Schaw, Chris

      2002-01-01

      This study compared 3 models of association between personality, personal model beliefs, and self-care in a cross-sectional design. These models were as follows: (a) Emotional stability determines self-care indirectly through personal model beliefs, and conscientiousness is a direct predictor of ....... Participants (N = 358, aged 12-30 years) with Type 1 diabetes completed measures of personality, personal model beliefs, and self-care. Structural equation modeling indicated that Model C was the best fit to the data....

    3. Entrepreneurial personality and entrepreneurial behaviour

      Directory of Open Access Journals (Sweden)

      Marcela Rodica LUCA

      2017-07-01

      Full Text Available The paper presents a literature analysis concerning the concept of entrepreneurial personality. Several topics are discussed, such as: entrepreneurship, entrepreneurial personality, personality traits and factors associated with entrepreneurship, context variables influencing entrepreneurial behaviour, psychological explanations of entrepreneurial behaviour.

    4. Proposed changes in personality and personality disorder assessment and diagnosis for DSM-5 part I: description and rationale

      NARCIS (Netherlands)

      Skodol, A.E.; Clark, L.A.; Bender, D.S.; Krueger, R.F.; Morey, L.C.; Verheul, R.; Alarcon, R.D.; Bell, C.C.; Siever, L.J.; Oldham, J.M.

      2011-01-01

      A major reconceptualization of personality psychopathology has been proposed for DSM-5 that identifies core impairments in personality functioning, pathological personality traits, and prominent pathological personality types. A comprehensive personality assessment consists of four components:

    5. Association of clinical androgen excess with radial artery intima media thickness in women with polycystic ovary syndrome.

      Science.gov (United States)

      Yilmaz, S A; Kebapcilar, A; Koplay, M; Kerimoglu, O S; Pekin, A T; Gencoglu, B; Dogan, N U; Celik, C

      2015-06-01

      This study explores the relationship between clinical cardiovascular risk factors and clinical androgen excess, with direct comparison to radial artery intima media thickness (rIMT). rIMT of 91 patients with polycystic ovary syndrome (PCOS) were compared with 72 healthy women. Patients were divided into three groups with regard to body mass index (BMI). Group1 = 56 women (31 controls and 25 PCOS) with low BMI(18-22.49 kg/m(2)), Group2 = 36 women (15 controls and 21 PCOS) with normal BMI (22.5-24.99 kg/m(2)) and Group3 = 71 women (26 controls and 45 PCOS) with high BMI (25-30 kg/m(2)). rIMT was significantly higher in patients with PCOS (p = 0.007). rIMT was significantly higher group1 and group3 in patients with PCOS compared to controls (p = 0.007 and p = 0.042, respectively). There was a significant positive association between rIMT levels and fT in women with PCOS in group1 (r = 0.24, p = 0.04). rIMT levels correlated to fT levels in women with PCOS in group3 (r = 0.32, p = 0.03). Modified Ferriman-Gallwey (mFG) scores demonstrated a positive association with free testosterone, total testosterone, free androgen index, waist circumference (WC), LH levels, insulin levels, Homeostasis Model Assessment index(HOMA-IR), rIMT and a negative correlation with sex hormone binding globulin in group1 and group2. mFG scores demonstrated a positive association with free testosterone (r = 0.33, p = 0.029) in group3, but no association was found between mFG and WC, HOMA-IR in group3. Our findings indicate that clinical androgen excess may be associated with cardiovascular disease in patients with PCOS.

    6. Leukocyte telomere length and personality: associations with the Big Five and Type D personality traits.

      Science.gov (United States)

      Schoormans, D; Verhoeven, J E; Denollet, J; van de Poll-Franse, L; Penninx, B W J H

      2018-04-01

      Backgrounds Accelerated cellular ageing, which can be examined by telomere length (TL), may be an overarching mechanism underlying the association between personality and adverse health outcomes. This 6-year longitudinal study examined the relation between personality and leukocyte telomere length (LTL) across time among adults with a wide age-range. Data from the Netherlands Study of Depression and Anxiety were used and included patients with a depression and/or anxiety disorder and healthy controls. Overall, 2936 persons (18-65 years, 66% female) had data on LTL at baseline and 1883 persons had LTL at 6-year follow-up. The Big Five personality traits (neuroticism, extraversion, openness to experience, agreeableness, and conscientiousness) and Type D personality were assessed. Neuroticism was negatively (B = -2.11, p = 0.03) and agreeableness was positively (B = 3.84, p = 0.03) related to LTL measured across two time points, which became just non-significant after adjusting for somatic health, lifestyle factors, and recent life stress (B = -1.99, p = 0.06; and B = 3.01, p = 0.10). Type D personality was negatively (B = -50.16, p Big Five traits high neuroticism and low agreeableness, and Type D personality were associated with shorter LTL measured across a 6-year period. Associations with the Big Five traits became non-significant after controlling for somatic health, lifestyle factors, and recent life stress, yet similar trends were observed. Type D personality remained independently associated with shorter LTL after full adjustment.

    7. Moving Field Guides

      Science.gov (United States)

      Cassie Meador; Mark Twery; Meagan. Leatherbury

      2011-01-01

      The Moving Field Guides (MFG) project is a creative take on site interpretation. Moving Field Guides provide an example of how scientific and artistic endeavors work in parallel. Both begin with keen observations that produce information that must be analyzed, understood, and interpreted. That interpretation then needs to be communicated to others to complete the...

    8. Methodology review: evaluating person fit

      NARCIS (Netherlands)

      Meijer, R.R.; Sijtsma, Klaas

      2001-01-01

      Person-fit methods based on classical test theory-and item response theory (IRT), and methods investigating particular types of response behavior on tests, are examined. Similarities and differences among person-fit methods and their advantages and disadvantages are discussed. Sound person-fit

    9. Making School Development Credible. Text, Context, Irony

      Directory of Open Access Journals (Sweden)

      Mats Börjesson

      2012-01-01

      Full Text Available

      The article argues for the importance of an open, reflexive-methodological approach when switching between studying text, context and researcher activity. Close linguistic analysis can benefit from being linked with the researcher’s contextualisation of his empirical material as well as with more distanced readings. The more specific starting point for this article is that school development, like other similar terms such as school improvement and the like, makes use of linguistic building blocks with which whole narratives about today’s and tomorrow’s schools can be constructed. The subject of the study is a short text issued by the Swedish Schools Inspectorate (Skolinspektionen. Government language changes according to the authorities’ role in society and their own definitions of their functions, and an important aspect here is the legitimacy of the authorities’ texts. By means of various kinds of close linguistic analysis, the above-mentioned text is studied with regard to choice of categories, hierarchies of modalisation and the rhetorical effects of different types of formulations in a broader political-social landscape. The article concludes with a reflective discussion on the relationship between government language and irony as a stylistic device – a device that is based on the results of the close empirical analysis.[i]

      <div>

      <div>

      [i] The article is part of the project ”School  Development as Narrative”, funded by the Swedish Research Council. The author would like to thank the two reviewers for very valuable comments.

      div>>

    10. Seleção de Fungicidas para Controle de Oídio em Eucalipto Selection of Fungicides for Control of Eucalypt Powdery Mildew

      Directory of Open Access Journals (Sweden)

      Rafaela Mazur Bizi

      2011-03-01

      Full Text Available <div>O objetivo deste estudo foi encontrar fungicidas eficientes contra o oídio do eucalipto. Foram testados os fungicidas chlorothalonil (2 g/l, fenarimol (0,5 ml/l, enxofre (3 g/l, tebuconazole (1 ml/l, propiconazol 12,5% + trifloxistrobina 12,5% (0,6 ml/l, benzothiadiazol (1g/l, piraclostrobina 13,3% + epoxiconazol 5% (1ml/l e triadimenol (1 ml/l. Os fungicidas foram pulverizados em 30 mudas por tratamento de Eucalyptus benthamii, naturalmente infectadas. A doença foi avaliada aos 9, 16, 23, 30 e 37 dias após serem colocadas em um ambiente infectado, onde os sintomas foram classificados em uma escala de notas que variam de 0 (ausência de sintomas a 4 (sintoma muito forte. Os melhores tratamentos foram piraclostrobina + epoxiconazol, propiconazol + trifloxistrobina e triadimenol, apresentando um índice médio de infecção de 0,39 e 0,63 e 1,01, respectivamente.  div>>The objective of this study was to find effective fungicides against eucalypt powdery mildew. Fungicides tested were chlorothalonil, fenarimol, sulfur, tebuconazole, propiconazole, benzothiazole, pyraclostrobin + epoxiconazole and triadimenol. These fungicides were sprayed on Eucalyptus benthamii seedlings in a greenhouse infested with powdery mildew. Severity was evaluated at 9, 16, 23, 30 and 37 days after spraying, classifying symptoms observed with a scale 0 (symptoms absent to 4 (strong symptoms. Best treatments were obtained with pyraclostrobin + epoxiconazole, propiconazole + trifloxystrobin and triadimenol, with an infection index average of 0.39, 0.63 and 1.01, respectively.div>

    11. Personalized ventilation

      DEFF Research Database (Denmark)

      Melikov, Arsen Krikor

      2004-01-01

      microenvironment. Furthermore, HVAC systems should be designed to protect occupants from airborne transmission of infectious agents that may be present in exhaled air. Personalized ventilation is a new development in the field of HVAC and has the potential to fulfill the above requirements. This paper reviews...... existing knowledge on performance of personalized ventilation (PV) and on human response to it. The airflow interaction in the vicinity of the human body is analyzed and its impact on thermal comfort and inhaled air quality is discussed together with control strategies and the application of PV in practice...

    12. Professional tools and a personal touch - experiences of physical therapy of persons with migraine.

      Science.gov (United States)

      Rutberg, Stina; Kostenius, Catrine; Öhrling, Kerstin

      2013-09-01

      The aim was to explore the lived experience of physical therapy of persons with migraine. Data were collected by conducting narrative interviews with 11 persons with migraine. Inspired by van Manen, a hermeneutic phenomenological method was used to analyse the experiences of physical therapy which these persons had. Physical therapy for persons with migraine meant making an effort in terms of time and energy to improve their health by meeting a person who was utilising his or her knowledge and skill to help. Being respected and treated as an individual and having confidence in the physical therapist were highlighted aspects. The analysis revealed a main theme, "meeting a physical therapist with professional tools and a personal touch". The main theme included four sub-themes, "investing time and energy to feel better", "relying on the competence of the physical therapist", "wanting to be treated and to become involved as an individual" and "being respected in a trustful relationship". The therapeutic relationship with the physical therapist is important and the findings of this study can increase awareness about relational aspects of physical therapy and encourage thoughtfulness among physical therapists and other healthcare professionals interacting with persons with migraine. Physical therapists use both professional tools and a personal touch in their interaction with persons with migraine and this article can increase physical therapists' awareness and encourage thoughtfulness in their professional practice. Being respected and treated as an individual and having confidence in the physical therapist are important aspects of the therapeutic relationship and indicate a need for patient-centred care. By making the effort of spending the time and energy required, physical therapy could be a complement or an alternative to medication to ease the consequences of migraine.

    13. Personality and externalizing behavior in the transition to young adulthood: the additive value of personality facets.

      Science.gov (United States)

      Klimstra, Theo A; Luyckx, Koen; Hale Iii, William W; Goossens, Luc

      2014-08-01

      The directionality of effects in the associations between personality and externalizing behavior (i.e., delinquency, soft drugs use, and alcohol abuse) is unclear. Moreover, previous studies only examined personality trait domains when examining these associations, whereas personality facets underlying these broad domains provide more specificity. To address these limitations, the present study examined the directionality of effects between externalizing behavior and personality while employing a facet-level approach to personality. Cross-lagged panel models were employed to four annual measurement waves of longitudinal data on 485 Belgian-Caucasian late adolescents (87.4 % female; M age = 18.63 years, SD = 0.61). Participants filled out the NEO-FFI as a measure of personality, the Deviant Behavior Scale as a measure of delinquency, and single items for soft drugs use and alcohol abuse on all four measurement occasions. The incremental value of personality facets over broad trait domains was demonstrated, as it was often the case that only some, but not all, facets underlying a specific trait domain were significantly associated with specific externalizing behaviors. Furthermore, linkages between personality and externalizing behavior were shown to be complex. Depending on the personality trait domain or facet and the specific behavior under investigation, the directionality of effects may differ. To capture the full complexity of the linkages between personality and externalizing behavior, a facet approach to personality is recommended. This information is potentially important for clinicians, as it indicates which specific aspects of a broad trait domain affect, and are affected by, specific externalizing behaviors.

    14. The impact of personality on person-centred care: a study of care staff in Swedish nursing homes.

      Science.gov (United States)

      Elfstrand Corlin, Tinna; Kajonius, Petri J; Kazemi, Ali

      2017-06-01

      In this study, we explore how personal and situational factors relate to the provision of person-centred care (PCC) in nursing homes. Specifically, we focus on the relationship between the care staff's personality traits and provision of PCC and to what extent perceptions of the working environment influences this relationship. The ultimate goal of elderly care is to meet the older person's needs and individual preferences (PCC). Interpersonal aspects of care and the quality of relationship between the care staff and the older person are therefore central in PCC. A cross-sectional Swedish sample of elderly care staff (N = 322) completed an electronic survey including measures of personality (Mini-IPIP) and person-centred care (Individualized Care Inventory, ICI). A principal component analysis was conducted on the ICI-data to separate the user orientation (process quality) of PCC from the preconditions (structure quality) of PCC. Among the five factors of personality, neuroticism was the strongest predictor of ICI user orientation. ICI preconditions significantly mediated this relationship, indicating the importance of a supportive working environment. In addition, stress was introduced as a potential explanation and was shown to mediate the impact of neuroticism on ICI preconditions. Personality traits have a significant impact on user orientation, and the perception of a supportive and stress free working environment is an important prerequisite for achieving high-quality person-centred elderly care. Understanding how personality is linked to the way care staff interacts with the older person adds a new perspective on provision of person-centred elderly care. © 2016 John Wiley & Sons Ltd.

    15. A cost-effective technique for integrating personal radiation dose assessment with personal gravimetric sampling

      International Nuclear Information System (INIS)

      Strydom, R.; Rolle, R.; Van der Linde, A.

      1992-01-01

      During recent years there has been an increasing awareness internationally of radiation levels in the mining and milling of radioactive ores, including those from non-uranium mines. A major aspect of radiation control is concerned with the measurement of radiation levels and the assessment of radiation doses incurred by individual workers. Current techniques available internationally for personnel monitoring of radiation exposures are expensive and there is a particular need to reduce the cost of personal radiation monitoring in South African gold mines because of the large labour force employed. In this regard the obvious benefits of integrating personal radiation monitoring with existing personal monitoring systems already in place in South African gold mines should be exploited. A system which can be utilized for this purpose is personal gravimetric sampling. A new cost-effective technique for personal radiation monitoring, which can be fully integrated with the personal gravimetric sampling strategy being implemented on mines, has been developed in South Africa. The basic principles of this technique and its potential in South African mines are described. 9 refs., 7 figs

    16. Acculturation, personality, and psychological adjustment.

      Science.gov (United States)

      Ahadi, Stephan A; Puente-Díaz, Rogelio

      2011-12-01

      Two studies investigated relationships between traditional indicators of acculturation, cultural distance, acculturation strategies, and basic dimensions of personality as they pertain to psychological adjustment among Hispanic students. Although personality characteristics have been shown to be important determinants of psychological well-being, acculturation research has put less emphasis on the role of personality in the well-being of immigrants. Hierarchical regression analysis showed that basic dimensions of personality such as extraversion and neuroticism were strongly related to psychological adjustment. Acculturation strategies did not mediate the effect of personality variables, but cultural resistance made a small, independent contribution to the explanation of some aspects of negative psychological adjustment. The implications of the results were discussed.

    17. Chronic vulvovaginitis in women older than 50 years: analysis of a prospective database.

      Science.gov (United States)

      Nyirjesy, Paul; Leigh, Randi D; Mathew, Leny; Lev-Sagie, Ahinoam; Culhane, Jennifer F

      2012-01-01

      This study aimed to examine differences in symptoms and diagnoses between women 50 years and younger and women older than 50 years who have chronic vulvovaginal complaints. New patients of the Drexel University Vaginitis Center with chronic vulvovaginal complaints were eligible. Participants underwent a standardized medical evaluation and completed detailed questionnaires. Data were analyzed using the t test, χ test, and the Fisher exact test. Subjects were 469 women aged 18 to 79 years. Subjects 50 years and younger (group A) were more likely to complain of vaginal itching and were less likely to complain of burning, irritation, or soreness (p ≤ .05 for all). Subjects older than 50 years (group B) were more likely to be diagnosed with atrophic vaginitis (p = .000), desquamative inflammatory vaginitis (DIV; p = .001), lichen planus (LP; p = .000), and lichen sclerosus (p = .000). Diagnosis of LS, LP, or DIV was associated with increased likelihood of multiparity and decreased likelihood of a history of systemic estrogen use. Postmenopausal women are more likely than premenopausal women to be diagnosed with DIV, LP, or LS. Both childbirth and estrogen nonuse were associated with the occurrence of these latter 3 conditions.

    18. Multifocus microscopy with precise color multi-phase diffractive optics applied in functional neuronal imaging.

      Science.gov (United States)

      Abrahamsson, Sara; Ilic, Rob; Wisniewski, Jan; Mehl, Brian; Yu, Liya; Chen, Lei; Davanco, Marcelo; Oudjedi, Laura; Fiche, Jean-Bernard; Hajj, Bassam; Jin, Xin; Pulupa, Joan; Cho, Christine; Mir, Mustafa; El Beheiry, Mohamed; Darzacq, Xavier; Nollmann, Marcelo; Dahan, Maxime; Wu, Carl; Lionnet, Timothée; Liddle, J Alexander; Bargmann, Cornelia I

      2016-03-01

      Multifocus microscopy (MFM) allows high-resolution instantaneous three-dimensional (3D) imaging and has been applied to study biological specimens ranging from single molecules inside cells nuclei to entire embryos. We here describe pattern designs and nanofabrication methods for diffractive optics that optimize the light-efficiency of the central optical component of MFM: the diffractive multifocus grating (MFG). We also implement a "precise color" MFM layout with MFGs tailored to individual fluorophores in separate optical arms. The reported advancements enable faster and brighter volumetric time-lapse imaging of biological samples. In live microscopy applications, photon budget is a critical parameter and light-efficiency must be optimized to obtain the fastest possible frame rate while minimizing photodamage. We provide comprehensive descriptions and code for designing diffractive optical devices, and a detailed methods description for nanofabrication of devices. Theoretical efficiencies of reported designs is ≈90% and we have obtained efficiencies of > 80% in MFGs of our own manufacture. We demonstrate the performance of a multi-phase MFG in 3D functional neuronal imaging in living C. elegans.

    19. Relationships: empirical contribution. Understanding personality pathology in adolescents: the five factor model of personality and social information processing.

      Science.gov (United States)

      Hessels, Christel; van den Hanenberg, Danique; de Castro, Bram Orobio; van Aken, Marcel A G

      2014-02-01

      This study seeks to integrate two research traditions that lie at the base of the understanding of personality pathology in adolescents. The first research tradition refers to normal personality according to the Five Factor Model (FFM). The second tradition specifies the key feature of personality disorder as the capacity to mentalize, which can be reflected in Social Information Processing (SIP). In a clinical sample of 96 adolescents, the authors investigated response generation, coping strategy, and memories of past frustrating experiences as part of SIP, as mediator in the relationship between personality and personality pathology, and a possible moderating role of personality on the relationship between SIP and personality pathology. The hypothesized mediation, by which the effects of personality dimensions on personality pathology was expected to be mediated by SIP variables, was found only for the effect of Neuroticism, most specifically on BPD, which appeared to be mediated by memories the patients had about past frustrating conflict situations with peers. Some moderating effects of personality on the relationship between SIP variables and personality pathology were found, suggesting that high Agreeableness and sometimes low Neuroticism can buffer this relationship. These results suggest that personality dimensions and social cognitions both independently and together play a role in adolescents' personality pathology.

    20. A Twin Study of Normative Personality and DSM-IV Personality Disorder Criterion Counts: Evidence for Separate Genetic Influences.

      Science.gov (United States)

      Czajkowski, Nikolai; Aggen, Steven H; Krueger, Robert F; Kendler, Kenneth S; Neale, Michael C; Knudsen, Gun Peggy; Gillespie, Nathan A; Røysamb, Espen; Tambs, Kristian; Reichborn-Kjennerud, Ted

      2018-03-21

      Both normative personality and DSM-IV personality disorders have been found to be heritable. However, there is limited knowledge about the extent to which the genetic and environmental influences underlying DSM personality disorders are shared with those of normative personality. The aims of this study were to assess the phenotypic similarity between normative and pathological personality and to investigate the extent to which genetic and environmental influences underlying individual differences in normative personality account for symptom variance across DSM-IV personality disorders. A large population-based sample of adult twins was assessed for DSM-IV personality disorder criteria with structured interviews at two waves spanning a 10-year interval. At the second assessment, participants also completed the Big Five Inventory, a self-report instrument assessing the five-factor normative personality model. The proportion of genetic and environmental liabilities unique to the individual personality disorder measures, and hence not shared with the five Big Five Inventory domains, were estimated by means of multivariate Cholesky twin decompositions. The median percentage of genetic liability to the 10 DSM-IV personality disorders assessed at wave 1 that was not shared with the Big Five domains was 64%, whereas for the six personality disorders that were assessed concurrently at wave 2, the median was 39%. Conversely, the median proportions of unique environmental liability in the personality disorders for wave 1 and wave 2 were 97% and 96%, respectively. The results indicate that a moderate-to-sizable proportion of the genetic influence underlying DSM-IV personality disorders is not shared with the domain constructs of the Big Five model of normative personality. Caution should be exercised in assuming that normative personality measures can serve as proxies for DSM personality disorders when investigating the etiology of these disorders.

    1. DefenseLink Feature: Personal Finance

      Science.gov (United States)

      Multimedia / Photos Videos Publications Bloggers DoD Websites Personal Finance Resources As part of the finance director said here recently. Story Security Expert Advises Troops to Safeguard Personal, Financial education in personal finance that commanders say goes a long way in promoting battle readiness. Story

    2. [Personal motif in art].

      Science.gov (United States)

      Gerevich, József

      2015-01-01

      One of the basic questions of the art psychology is whether a personal motif is to be found behind works of art and if so, how openly or indirectly it appears in the work itself. Analysis of examples and documents from the fine arts and literature allow us to conclude that the personal motif that can be identified by the viewer through symbols, at times easily at others with more difficulty, gives an emotional plus to the artistic product. The personal motif may be found in traumatic experiences, in communication to the model or with other emotionally important persons (mourning, disappointment, revenge, hatred, rivalry, revolt etc.), in self-searching, or self-analysis. The emotions are expressed in artistic activity either directly or indirectly. The intention nourished by the artist's identity (Kunstwollen) may stand in the way of spontaneous self-expression, channelling it into hidden paths. Under the influence of certain circumstances, the artist may arouse in the viewer, consciously or unconsciously, an illusionary, misleading image of himself. An examination of the personal motif is one of the important research areas of art therapy.

    3. Education for Flexible Personality

      Directory of Open Access Journals (Sweden)

      Bogomir Novak

      1998-12-01

      Full Text Available Flexible personality transforms both cultural environment and itself. Post-modern personality is both contemplative and active. On one hand, it is subject to inner imagination of a creative act, and on the other hand, to creation of a tangible product What is more, flexible personality is also autonomous, mature, healthy and well balanced, as well as stable and responsive to the demand for change. Due to ever quicker changes, flexible personality is a must. And it is a task. The impact of professional work of adults on the education of children, however, is being conditioned by the exrigid family and rigid enterprises or institutions in which adults are employed. Nevertheless, flexible educational style is not repressive, as it used to be, nor permissive and totally concentrated on the child. It is a choice between the two qualities. The educators' style is dependent on their attitude towards life (play and self-education and not only towards work. Nowadays, flexibility is a way towards quality management of social and personal changes.

    4. Can DSM-IV borderline personality disorder be diagnosed via dimensional personality traits? Implications for the DSM-5 personality disorder proposal.

      Science.gov (United States)

      Miller, Joshua D; Morse, Jennifer Q; Nolf, Kimberly; Stepp, Stephanie D; Pilkonis, Paul A

      2012-11-01

      The proposal for the diagnosis of personality disorders (PDs) in the Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-5;American Psychiatric Association, in preparation) involves, in part, the use of elevated scores on dimensional personality traits. For instance, the diagnosis of borderline personality disorder (BPD) in the DSM-5 will require evidence of self- and interpersonal impairment as well as elevated scores on traits of emotional lability, anxiousness, separation insecurity, depressivity, impulsivity, risk taking, and hostility. Using a sample of individuals from the community (N = 134), half of whom were receiving psychiatric treatment, we tested whether the summation of relevant personality trait scores, using data derived from a measure of the Five-Factor Model of personality (FFM), would result in a construct that corresponds to the Diagnostic and Statistical Manual of Mental Disorders, 4th ed. (DSM-IV, American Psychiatric Association, 2000) BPD construct as scored by expert consensus ratings. The DSM-IV and FFM BPD scores were significantly correlated (r = .60) and generated highly similar patterns of relations (ricc = .84) with key constructs from BPD's nomological network. These data should serve to allay concerns that the DSM-5's new diagnostic approach will be detrimental to the identification of BPD. (PsycINFO Database Record (c) 2012 APA, all rights reserved).

    5. Associations linking parenting styles and offspring personality disorder are moderated by parental personality disorder, evidence from China.

      Science.gov (United States)

      Cheng, Hui Green; Huang, Yueqin; Liu, Zhaorui; Liu, Baohua

      2011-08-30

      The aim of the study is to examine the association linking parenting and personality disorder controlling for parental personality disorder, and whether this association is moderated by parental PD. Data were from community-dwelling high school students aged 18 and above and their parents living in Beijing, China. A total of 181 cases and 2,605 controls were included in this study. Personality disorder in students was assessed via a two-stage approach, Personality Diagnostic Questionnaire as a screening tool and International Personality Disorder Examination as the diagnostic tool. Information about parenting was collected from students using Egna Minnen av. Betraffande Uppfostran. Negative parenting styles, e.g. rejective or over-protective parenting, were found to be associated with the occurrence of personality disorder. Conflictive parenting styles were also found to be associated with personality disorder. Generally stronger associations were found for students with parental personality disorder as compared to students without parental personality disorder. Findings from this study support the role of parenting in the occurrence of PD, especially for children with family history of personality disorder. Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.

    6. Stress and personality.

      Science.gov (United States)

      Lecic-Tosevski, D; Vukovic, O; Stepanovic, J

      2011-01-01

      Stress is an adaptation reaction of living organisms in response to internal or external threats to homeostasis. It is considered as a complex defence mechanism representing the final endpoint of numerous dynamic and interconnected factors of biological, psychological and social nature. Stress is not a simple, stimulus-response reaction, but the interaction between an individual and the environment, involving subjective perception and assessment of stressors, thus constituting a highly personalized process. Specific inherited characteristics, early experience in life, and particular, learned cognitive predispositions make individuals more or less susceptible to the effects of stressors. Resilience and vulnerability to stressors as well as intensity of stress response are greatly dependable on age, gender, intelligence, and numerous characteristics of personality, such as hardiness,locus of control, self-efficacy, self-esteem, optimism, hostility (component of type A personality)and type D traits (negative affectivity and social inhibition). To understand the relation between personality and stress, it is essential to recognize the impact of individual differences in the following four aspects: (1) choice or avoidance of environments that are associated with specific stressors, challenges or benefits, (2) way of interpreting a stressful situation and evaluating one's own abilities and capacities for proactive behaviour so as to confront or avoid it, (3) intensity of response to a stressor,and (4) coping strategies employed by the individual facing a stressful situation. Studies have recorded considerable consistency in coping strategies employed to confront stressful situations, independentlyof situational factors and in connection with permanent personality and temperamental traits,such as neuroticism, extraversion, sense of humour, persistence, fatalism, conscientiousness, andopenness to experience. Positive affect has been associated with positive reappraisal

    7. Generalized social phobia versus avoidant personality disorder : Differences in psychopathology, personality traits, and social and occupational functioning

      NARCIS (Netherlands)

      van Velzen, CJM

      2000-01-01

      Four groups of patients with social phobia (SP) were compared with regard to psychopathologic characteristics, personality traits, and social and occupational functioning. Fifteen persons with discrete social phobia without any personality disorder (DSP), 28 persons with generalized social phobia

    8. 7 CFR 33.2 - Person.

      Science.gov (United States)

      2010-01-01

      ... 7 Agriculture 2 2010-01-01 2010-01-01 false Person. 33.2 Section 33.2 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing... ISSUED UNDER AUTHORITY OF THE EXPORT APPLE ACT Definitions § 33.2 Person. Person means an individual...

    9. 28 CFR 41.31 - Handicapped person.

      Science.gov (United States)

      2010-07-01

      ... Persons § 41.31 Handicapped person. (a) Handicapped person means any person who has a physical or mental...: (1) Physical or mental impairment means: (i) Any physiological disorder or condition, cosmetic... disorder, such as mental retardation, organic brain syndrome, emotional or mental illness, and specific...

    10. *NEW* CRITICAL Windows Security patches

      CERN Multimedia

      2003-01-01

      On 3 October and 10 September 2003, Microsoft issued new CRITICAL security patches MS03-040 and MS03-039. They must be URGENTLY applied on ALL WINDOWS systems, which are not centrally managed for security patches. This includes Experiment computers, Home computers and Windows Portable and Desktop systems not running NICE. Details of the security holes and patches are at: MS03-039: http://cern.ch/it-div/news/hotfix-MS03-039.asp http://www.microsoft.com/technet/security/bulletin/MS03-039.asp MS03-040: http://cern.ch/it-div/news/hotfix-MS03-040.asp http://www.microsoft.com/technet/security/bulletin/MS03-040.asp

    11. Variáveis familiares e saúde em crianças de pais divorciados

      OpenAIRE

      Morais, Ana Paula Gonçalves de

      2007-01-01

      Dissertação de Mestrado em Psicologia (Especialização Psicologia da Saúde) O divórcio é um importante factor de risco para problemas de ajustamento e saúde na criança. O objectivo da presente investigação que se enquadra na perspectiva do modelo biopsicossocial é avaliar o ajustamento ao divórcio, problemas de comportamento, morbilidade psicológica, saúde física e psicossocial e a relação entre estas variáveis em crianças, na faixa etária dos 10 aos 12 anos, provenientes de famílias sep...

    12. TEORES SÉRICOS DE CORTISOL DE FÊMEAS CANINAS (Canis familiaris – LINNAEUS, 1758 SUBMETIDAS À CESARIANA SERIC LEVELS OF CORTISOL IN BITCHES (Canis familiaris – LINNAEUS, 1758 SUBMITTED TO AESARIAN SECTION Niveles séricos del cortisol en perras (Canis familiaris – Linnaeus, 1758 sometidas a cesárea

      Directory of Open Access Journals (Sweden)

      Diogo José Cardilli

      2009-12-01

      Full Text Available <div>Cadelas submetidas à cesariana, por estarem em situação diferente da fisiológica, podem apresentar alterações séricas para se adaptarem a essa nova condição de estresse. Dentre as possíveis alterações, encontram-se as concentrações de cortisol durante o período periparto. Sendo assim, o objetivo deste estudo foi quantificar os teores séricos do cortisol de cadelas submetidas à cesariana na fase de parto e pós-parto (no dia do ato cirúrgico ou parto, 24 horas, 48 horas e dez dias após. O método de radioimunoensaio foi utilizado para a realização da dosagem do cortisol sérico (nos períodos já descritos. Realizou-se a análise estatística por meio dos testes t e Tukey. O teor de cortisol sérico apresentou diferença (p< 0,05 no dia da cesariana (6,83 µg/dL, porém não diferiu (p> 0,05 nos dias subsequentes (1,82 µg/dL, 24 horas após; 1,38 µg/dL, 48 horas após; 1,48 µg/dL dez dias após. Os valores médios do grupo controle foram 3,43, 2,01, 3,59 e 1,72 µg/dL, após o parto, 24, 48 horas e dez dias após, respectivamente. O estresse devido à distocia elevou a liberação desse hormônio, voltando à normalidade nos dias subsequentes, porém o estresse cirúrgico não promoveu aumento na liberação de cortisol em cadelas submetidas à cesariana. Os animais do grupo controle apresentaram teores séricos de cortisol, nos devidos períodos, compatíveis com os citados pela literatura.div>>
      div>>PALAVRAS-CHAVES: Cadelas, cesariana, cortisol.div>>
      div> <div>Bitches submitted to caesarian section, for being in a physiological different situation, can present alterations to adapt to this new stress condition. Into possible alterations are cortisol levels during per partum period. So, the objectives of this study was to quantify seric cortisol of bitches submitted to caesarian section in partum and postpartum period (in the day of the partum or surgery , 24, 48 hours and 10 days later

    13. Fathers' personality and its interaction with children's personality as predictors of perceived parenting behavior six years later

      NARCIS (Netherlands)

      Prinzie, Peter; Dekovic, Maja; van den Akker, Alithe L.; de Haan, Amaranta D.; Stoltz, Sabine E. M. J.; Hendriks, A. A. Jolijn

      We investigated fathers' personality and its interaction with children's personality as predictors of adolescent perceived parenting behavior. Data were used from the Flemish Study on Parenting, Personality and Development including 353 children. At Time 1 fathers rated their personality whereas

    14. Personality Pathology of Adults With Autism Spectrum Disorder Without Accompanying Intellectual Impairment in Comparison to Adults With Personality Disorders.

      Science.gov (United States)

      Strunz, Sandra; Westphal, Linda; Ritter, Kathrin; Heuser, Isabella; Dziobek, Isabel; Roepke, Stefan

      2015-12-01

      Differentiating autism spectrum disorders (ASDs) without accompanying intellectual impairment from personality disorders is often challenging. Identifying personality traits and personality pathology specific to ASD might facilitate diagnostic procedure. We recruited a sample of 59 adults with ASD without accompanying intellectual impairment, 62 individuals with narcissistic personality disorder, 80 individuals with borderline personality disorder, and 106 nonclinical controls. Personality traits, measured with the neo-personality inventory-revised (NEO-PI-R), and personality pathology, measured with the dimensional assessment of personality pathology (DAPP-BQ), were assessed. Personality traits and personality pathology specific to ASD could be identified. ASD individuals scored significantly lower on the NEO-PI-R scales extraversion and openness to experience and significantly higher on the DAPP-BQ scales inhibitedness and compulsivity relative to all other groups. Diagnostic implications are discussed.

    15. Personality and Prosocial Behavior

      DEFF Research Database (Denmark)

      Hilbig, Benjamin E; Glöckner, Andreas; Zettler, Ingo

      2014-01-01

      Concerning the dispositional determinants of prosocial behavior and cooperation, work based on the classic 5 personality factors, and especially Agreeableness, has turned out somewhat inconsistent. A clearer picture has emerged from consideration of the HEXACO model of personality-though supported......-Humility (and certain aspects of five-factor Agreeableness) account for prosocial behavior-thus explaining previous inconsistencies and providing a more nuanced understanding of the links between basic personality and prosocial or cooperative behavior. (PsycINFO Database Record (c) 2014 APA, all rights reserved)....

    16. Fab the coming revolution on your desktop : from personal computers to personal fabrication

      CERN Document Server

      Gershenfeld, Neil

      2005-01-01

      What if you could someday put the manufacturing power of an automobile plant on your desktop? According to Neil Gershenfeld, the renowned MIT scientist and inventor, the next big thing is personal fabrication-the ability to design and produce your own products, in your own home, with a machine that combines consumer electronics and industrial tools. Personal fabricators are about to revolutionize the world just as personal computers did a generation ago, and Fab shows us how.

    17. A folk-psychological ranking of personality facets

      Directory of Open Access Journals (Sweden)

      Eka Roivainen

      2016-10-01

      Full Text Available Background Which personality facets should a general personality test measure? No consensus exists on the facet structure of personality, the nature of facets, or the correct method of identifying the most significant facets. However, it can be hypothesized (the lexical hypothesis that high frequency personality describing words more likely represent important personality facets and rarely used words refer to less significant aspects of personality. Participants and procedure A ranking of personality facets was performed by studying the frequency of the use of popular personality adjectives in causal clauses (because he is a kind person on the Internet and in books as attributes of the word person (kind person. Results In Study 1, the 40 most frequently used adjectives had a cumulative usage frequency equal to that of the rest of the 295 terms studied. When terms with a higher-ranking dictionary synonym or antonym were eliminated, 23 terms remained, which represent 23 different facets. In Study 2, clusters of synonymous terms were examined. Within the top 30 clusters, personality terms were used 855 times compared to 240 for the 70 lower-ranking clusters. Conclusions It is hypothesized that personality facets represented by the top-ranking terms and clusters of terms are important and impactful independent of their correlation with abstract underlying personality factors (five/six factor models. Compared to hierarchical personality models, lists of important facets probably better cover those aspects of personality that are situated between the five or six major domains.

    18. Adult Personality Development: Dynamics and Processes

      OpenAIRE

      Diehl, Manfred; Hooker, Karen

      2013-01-01

      The focus of this special issue of Research in Human Development is on adult personality and how personality may contribute to and be involved in adult development. Specifically, the contributions in this issue focus on the links between personality structures (e.g., traits) and personality processes (e.g., goal pursuit, self--regulation) and emphasize the contributions that intensive repeated measurement approaches can make to the understanding of personality and development across the adult...

    19. Modified crisis intervention for personality disorder.

      Science.gov (United States)

      Rudnick, A

      1998-01-01

      This study proposes that the goal of crisis intervention for persons with personality disorders should be to return them to their pre-crisis level of functioning, even though this is maladaptive. This is contrasted with standard crisis intervention, which aims to return normal or neurotic persons to their pre-crisis normal or neurotic functioning, usually by means of few and short-term therapeutic encounters. The modification proposed costs more time and resources in persons with personality disorders in crisis and fits the intervention to the personality type. This is illustrated by the case of Eve, a patient in crisis, whose pre-crisis functioning was maladaptive because of a dependent personality disorder. The goal of (modified) crisis intervention in this case was to return the patient to her dependent lifestyle, by means of pharmacotherapy combined with intensive supportive psychotherapy during 3-4 months of partial (day) hospitalization. The special nature of crisis in personality disorders is discussed.

    20. GENDER ROLE AND PERSONALITY DISORDERS

      Science.gov (United States)

      Klonsky, E. David; Jane, J. Serrita; Turkheimer, Eric; Oltmanns, Thomas F.

      2015-01-01

      Many researchers have hypothesized relationships between personality disorders and gender role (i.e., masculinity and femininity). However, research has not addressed if people who are masculine or feminine more often meet the criteria for personality disorders. The present study examined whether college students (N = 665, 60% women) higher in masculinity or femininity more often exhibited features of the 10 DSM-IV personality disorders. Feminine men exhibited more features of all the personality disorders except antisocial. Dependent traits were associated with higher femininity and lower masculinity. Antisocial traits were associated with masculinity. Both men and women who typically behaved consistent with their gender had more narcissistic and histrionic features, whereas participants who typically behaved unlike their gender had more features of the Cluster A personality disorders. PMID:12489312