WorldWideScience

Sample records for mexico land withdrawal

  1. 77 FR 8895 - Public Land Order No. 7788; Withdrawal of National Forest System Land for the Red Cloud...

    Science.gov (United States)

    2012-02-15

    ... Land Order No. 7788; Withdrawal of National Forest System Land for the Red Cloud Campground; New Mexico... Cloud Campground within the Cibola National Forest, and to protect a capital investment in the... (FIRS) at 1-800-877-8339 to contact either of the above individuals during normal business hours. The...

  2. Impacts of Land Cover and Land Use Change on the Hydrology of the US-Mexico Border Region, 1992-2011

    Science.gov (United States)

    Bohn, T. J.; Vivoni, E. R.; Mascaro, G.; White, D. D.

    2016-12-01

    The semi-arid US-Mexico border region has been experiencing rapid urbanization and agricultural expansion over the last several decades, due in part to the lifting of trade barriers of the 1994 North American Free Trade Agreement (NAFTA), placing additional pressures on the region's already strained water resources. Here we examine the effects of changes in land cover/use over the period 1992-2011 on the region's hydrology and water resources, using the Variable Infiltration Capacity (VIC) model with an irrigation module to estimate both natural and anthropogenic water fluxes. Land cover has been taken from the National Land Cover Database (NLCD) over the US, and from the Instituto Nacional de Estadística y Geografía (INEGI) database over Mexico, for three snapshots: 1992/3, 2001/2, and 2011. We have performed 3 simulations, one per land cover snapshot, at 6 km resolution, driven by a gridded observed meteorology dataset and a climatology of land surface characteristics derived from remote sensing products. Urban water withdrawal rates were estimated from literature. The primary changes in the region's water budget over the period 1992-2011 consisted of: (1) a shift in agricultural irrigation water withdrawals from the US to Mexico, accompanied by similar shifts in runoff (via agricultural return flow) and evapotranspiration; and (2) a 50% increase in urban water withdrawals, concentrated in the US. Because groundwater supplied most of the additional agricultural withdrawals, and occurred over already over-exploited aquifers, these changes call into question the sustainability of the region's land and water management. By synthesizing the implications of these hydrologic changes, we present a novel view of how NAFTA has altered the US-Mexico border region, possibly in unintended ways.

  3. 75 FR 41237 - Public Land Order No. 7746; Withdrawal of Public Lands, South Fork of the American River; California

    Science.gov (United States)

    2010-07-15

    ... DEPARTMENT OF THE INTERIOR Bureau of Land Management [LLCAC08000-L1430000-ET0000; CACA 41334] Public Land Order No. 7746; Withdrawal of Public Lands, South Fork of the American River; California AGENCY: Bureau of Land Management, Interior. ACTION: Public Land Order. SUMMARY: This order withdraws 2...

  4. 75 FR 26788 - Public Land Order No. 7742; Withdrawal of Public Land for the Manning Canyon Tailings Repository; UT

    Science.gov (United States)

    2010-05-12

    ... 79765] Public Land Order No. 7742; Withdrawal of Public Land for the Manning Canyon Tailings Repository... period of 5 years to protect the integrity of the Manning Canyon Tailings Repository and surrounding... withdrawal is to protect public health and safety and the Federal investment in the Manning Canyon Tailings...

  5. 77 FR 47089 - Public Land Order No. 7795; Withdrawal of Public Lands, Clear Creek Serpentine Area of Critical...

    Science.gov (United States)

    2012-08-07

    ... DEPARTMENT OF THE INTERIOR Bureau of Land Management [LLCAC09000, 16100000.DQ; CACA 051408] Public Land Order No. 7795; Withdrawal of Public Lands, Clear Creek Serpentine Area of Critical Environmental Concern; California AGENCY: Bureau of Land Management, Interior. ACTION: Public Land Order. SUMMARY: This...

  6. 78 FR 3913 - Public Land Order No. 7807: Withdrawal of Public Lands for the Camp Michael Monsoor Mountain...

    Science.gov (United States)

    2013-01-17

    ..., location, and entry under the general land laws, including the United States mining laws, for a period of... Training Facility. This withdrawal also transfers administrative jurisdiction of the lands to the... entry under the general land laws, including the United States mining laws, but not from leasing under...

  7. New Mexico Federal Lands

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This map layer consists of federally owned or administered lands of the United States, Puerto Rico, and the U.S. Virgin Islands. Only areas of 640 acres or more are...

  8. Waste Isolation Pilot Plant Land Withdrawal Act of 1988. Introduced in the Senate, One Hundredth Congress, Second Session, Calendar No. 957, September 22, 1988

    International Nuclear Information System (INIS)

    Anon.

    1988-01-01

    The Committee on Energy and Natural Resources have amended S.1272 whose purpose is to withdraw 10,240 acres of land in Eddy County, New Mexico for the exclusive use of the Department of Energy for construction, operation, decommissioning, and post-decommissioning control of the Waste Isolation Pilot Plant. These lands are currently managed by the Department of the Interior. Full text of the amendments recommended by the Committee is presented along with a summary of major provisions of S.1272. Amendments would provide for an Environmental Evaluation Group oversight, limit the volume of waste stored at WIPP, require compliance with EPA standards, ban high-level radioactive waste experiments at WIPP, regulate transport of waste to WIPP, direct the DOE to consult with the Governor of New Mexico, require full-scale tests on transport packages, prevent shipments from Rocky Flats to Idaho Engineering Lab after WIPP begins operation, limit shipments of waste to Idaho, and establish the Environmental Evaluation Group by Federal contract

  9. 77 FR 70463 - Public Land Order No. 7801; Withdrawal of Public Lands for Protection of Proposed Expansion of...

    Science.gov (United States)

    2012-11-26

    ... DEPARTMENT OF THE INTERIOR [LLCAD08000-L14300000-ET0000; CACA 51737] Public Land Order No. 7801; Withdrawal of Public Lands for Protection of Proposed Expansion of Twentynine Palms, CA Correction In notice document 2012-23479 beginning on page 58864 of the issue of Monday, September 24, 2012 make the following...

  10. Las Tierras de Nuevo Mexico. [The Lands of New Mexico.

    Science.gov (United States)

    Swadesh, Frances Leon; And Others

    New Mexico was inhabited thousands of years ago. Each group of settlers saw the land in distinct ways. For some, its beauty consisted of its quality, the abundance of water, and the hope of a good harvest. For others, its beautiful sites were of more importance. Thus, each group established its own manner of living on the land and of using it.…

  11. New Mexico: The Land of Enchantment

    Science.gov (United States)

    McKay, Sandra

    2009-01-01

    New Mexico, a state of brown plains and sand deserts, is nicknamed "The Land of Enchantment." One reason is that the very starkness of the land adds to its enchantment. Another reason is that the rich history of the state has resulted in a landscape filled with remnants of the Pueblo people, Spanish colonizers, and Mexican settlers.

  12. List of recent land mammals from Mexico, 2014

    Science.gov (United States)

    Ramirez-Pulido, Jose; Gonzalez-Ruiz, Noe; Gardner, Alfred L.; Arroyo-Cabrales, Joaquin

    2014-01-01

    We provide an updated list of the Recent land mammals of Mexico and include information on the taxonomy of certain species, and where appropriate, the endemic and threatened status of all species listed. Several taxonomic and nomenclatural changes have been made since publication of the last list of the Mexican terrestrial mammalian fauna. Within the period from 2005 to present, there have been at least 209 changes concerning the nomenclature of this fauna; these we evaluated in this paper. The land mammals of Mexico comprise 168 genera, 496 species, and 881 subspecies.

  13. 78 FR 58555 - Public Land Order No. 7821; Withdrawal of National Forest System Land for Steamboat Rock Picnic...

    Science.gov (United States)

    2013-09-24

    ...; Withdrawal of National Forest System Land for Steamboat Rock Picnic Grounds; South Dakota AGENCY: Bureau of... the Steamboat Rock Picnic Grounds within the Black Hills National Forest in South Dakota. DATES... Steamboat Rock Picnic Grounds. Order By virtue of the authority vested in the Secretary of the Interior by...

  14. 75 FR 440 - Notice of Proposed Withdrawal and Opportunity for Public Meeting; New Mexico

    Science.gov (United States)

    2010-01-05

    ... withdraw 15 acres of National Forest System land from mining to protect the Red Cloud Campground on the... interpretive integrity of the Red Cloud Campground, within the Cibola National Forest, and to protect a capital... Forest at the above addresses during regular business hours, 8 a.m. to 4:45 p.m., Monday through Friday...

  15. Waste Isolation Pilot Plant land management plan

    International Nuclear Information System (INIS)

    1996-01-01

    On October 30, 1992, the WIPP Land Withdrawal Act became law. This Act transferred the responsibility for the management of the WIPP Land Withdrawal Area (WILWA) from the Secretary of the Interior to the Secretary of Energy. In accordance with sections 3(a)(1) and (3) of the Act, these lands open-quotes hor-ellipsis are withdrawn from all forms of entry, appropriation, and disposal under the public land laws hor-ellipsis close quotesand are reserved for the use of the Secretary of Energy open-quotes hor-ellipsis for the construction, experimentation, operation, repair and maintenance, disposal, shutdown, monitoring, decommissioning, and other activities, associated with the purposes of WIPP as set forth in the Department of Energy National Security and Military Applications of Nuclear Energy Act of 1980 and this Act.close quotes. As a complement to this LMP, a MOU has been executed between the DOE and the BLM, as required by section 4(d) of the Act. The state of New Mexico was consulted in the development of the MOU and the associated Statement of Work (SOW)

  16. Waste Isolation Pilot Plant land management plan

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-05-01

    On October 30, 1992, the WIPP Land Withdrawal Act became law. This Act transferred the responsibility for the management of the WIPP Land Withdrawal Area (WILWA) from the Secretary of the Interior to the Secretary of Energy. In accordance with sections 3(a)(1) and (3) of the Act, these lands {open_quotes}{hor_ellipsis}are withdrawn from all forms of entry, appropriation, and disposal under the public land laws{hor_ellipsis}{close_quotes}and are reserved for the use of the Secretary of Energy {open_quotes}{hor_ellipsis}for the construction, experimentation, operation, repair and maintenance, disposal, shutdown, monitoring, decommissioning, and other activities, associated with the purposes of WIPP as set forth in the Department of Energy National Security and Military Applications of Nuclear Energy Act of 1980 and this Act.{close_quotes}. As a complement to this LMP, a MOU has been executed between the DOE and the BLM, as required by section 4(d) of the Act. The state of New Mexico was consulted in the development of the MOU and the associated Statement of Work (SOW).

  17. Simulation of the Effects of Water Withdrawals, Wastewater Return Flows, and Land-Use Change on Streamflow in the Blackstone River Basin, Massachusetts and Rhode Island

    Science.gov (United States)

    Barbaro, Jeffrey R.

    2007-01-01

    Streamflow in many parts of the Blackstone River Basin in south-central Massachusetts and northern Rhode Island is altered by water-supply withdrawals, wastewater-return flows, and land-use change associated with a growing population. Simulations from a previously developed and calibrated Hydrological Simulation Program?FORTRAN (HSPF) precipitation-runoff model for the basin were used to evaluate the effects of water withdrawals, wastewater-return flows, and land-use change on streamflow. Most of the simulations were done for recent (1996?2001) conditions and potential buildout conditions in the future when all available land is developed to provide a long-range assessment of the effects of possible future human activities on water resources in the basin. The effects of land-use change were evaluated by comparing the results of long-term (1960?2004) simulations with (1) undeveloped land use, (2) 1995?1999 land use, and (3) potential buildout land use at selected sites across the basin. Flow-duration curves for these land-use scenarios were similar, indicating that land-use change, as represented in the HSPF model, had little effect on flow in the major tributary streams and rivers in the basin. However, land-use change?particularly increased effective impervious area?could potentially have greater effects on the hydrology, water quality, and aquatic habitat of the smaller streams in the basin. The effects of water withdrawals and wastewater-return flows were evaluated by comparing the results of long-term simulations with (1) no withdrawals and return flows, (2) actual (measured) 1996?2001 withdrawals and wastewater-return flows, and (3) potential withdrawals and wastewater-return flows at buildout. Overall, the results indicated that water use had a much larger effect on streamflow than did land use, and that the location and magnitude of wastewater-return flows were important for lessening the effects of withdrawals on streamflow in the Blackstone River Basin

  18. 76 FR 24513 - Public Land Order No. 7765; Partial Revocation Jupiter Inlet Lighthouse Withdrawal; Florida

    Science.gov (United States)

    2011-05-02

    ...] Public Land Order No. 7765; Partial Revocation Jupiter Inlet Lighthouse Withdrawal; Florida AGENCY... as part of the Jupiter Inlet Lighthouse Outstanding Natural Area. DATES: Effective Date: May 2, 2011... U.S.C. 1787), which created the Jupiter Inlet Lighthouse Outstanding Natural Area, and which...

  19. Land grants of New Mexico and the United States Forest Service

    Science.gov (United States)

    Carol Raish; Alice M. McSweeney

    2011-01-01

    The U.S. Forest Service (FS) has a long, shared history with the Spanish and Mexican land grants of northern New Mexico. The Treaty of Guadalupe Hidalgo, which ended the war between the United States and Mexico, was supposed to recognize and respect the property rights of the resident Hispano population. In many cases the intent of the Treaty was not honored. During...

  20. Magnitude and extent of land subsidence in central Mexico revealed by regional InSAR ALOS time-series survey

    Science.gov (United States)

    Chaussard, E.; Wdowinski, S.; Amelung, F.; Cabral-Cano, E.

    2013-05-01

    Massive groundwater extraction is very common in Mexico and is well known to result in land subsidence. However, most surveys dedicated to land subsidence focus on one single city, mainly Mexico City, and thus fail to provide a comprehensive picture of the problem. Here we use a space-based radar remote sensing technique, known as Interferometric Synthetic Aperture Radar (InSAR) to detect land subsidence in the entire central Mexico area. We used data from the Japanese satellite ALOS, processed over 600 SAR images acquired between 2007-2011 and produced over 3000 interferograms to cover and area of 200,000 km2 in central Mexico. We identify land subsidence in twenty-one areas, including seventeen cities, namely from east to west, Puebla, Mexico city, Toluca de Lerdo, Queretaro, San Luis de la Paz, south of San Luis de la Paz, Celaya, south of Villa de Reyes, San Luis Potosi, west of Villa de Arista, Morelia, Salamanca, Irapuato, Silao, Leon, Aguascalientes, north of Aguascalientes, Zamora de Hidalgo, Guadalajara, Ahuacatlan, and Tepic. Subsidence rates of 30 cm/yr are observed in Mexico City, while in the other locations typical rates of 5-10 cm/yr are noticed. Regional surveys of this type are necessary for the development of hazard mitigation plans and efficient use of ground-based monitoring. We additionally correlate subsidence with land use, surface geology, and faults distribution and suggest that groundwater extraction for agricultural, urban, and industrial uses are the main causes of land subsidence. We also reveal that the limits of the subsiding areas often correlate with existing faults, motion on these faults being driven by water extraction rather than by tectonic activity. In all the subsiding locations we observe high ground velocity gradients emphasizing the significant risks associated with land subsidence in central Mexico. Averaged 2007-2011 ground velocity map from ALOS InSAR time-series in central Mexico, revealing land subsidence in 21

  1. An Aerial Radiological Survey of the Yucca Mountain Project Proposed Land Withdrawal and Adjacent Areas

    International Nuclear Information System (INIS)

    Craig Lyons, Thane Hendricks

    2006-01-01

    An aerial radiological survey of the Yucca Mountain Project (YMP) proposed land withdrawal was conducted from January to April 2006, and encompassed a total area of approximately 284 square miles (73,556 hectares). The aerial radiological survey was conducted to provide a sound technical basis and rigorous statistical approach for determining the potential presence of radiological contaminants in the Yucca Mountain proposed Land withdrawal area. The survey site included land areas currently managed by the Bureau of Land Management, the U.S. Air Force as part of the Nevada Test and Training Range or the U.S. Department of Energy (DOE), National Nuclear Security Administration Nevada Site Office (NNSA/NSO) as part of the Nevada Test Site (NTS). The survey was flown at an approximate ground speed of 70 knots (36 meters per second), at a nominal altitude of 150 ft (46 m) above ground level, along a set of parallel flight lines spaced 250 ft (76 m) apart. The flight lines were oriented in a north-south trajectory. The survey was conducted by the DOE NNSA/NSO Remote Sensing Laboratory-Nellis, which is located in Las Vegas, Nevada. The aerial survey was conducted at the request of the DOE Office of Civilian Radioactive Waste Management. The primary contaminant of concern was identified by YMP personnel as cesium-137 ( 137 Cs). Due to the proposed land withdrawal area's proximity to the historical Nuclear Rocket Development Station (NRDS) facilities located on the NTS, the aerial survey system required sufficient sensitivity to discriminate between dispersed but elevated 137 Cs levels from those normally encountered from worldwide fallout. As part of that process, the survey also measured and mapped the exposure-rate levels that currently existed within the survey area. The inferred aerial exposure rates of the natural terrestrial background radiation varied from less than 3 to 22 microroentgens per hour. This range of exposure rates was primarily due to the surface

  2. Historic land use and grazing patterns in northern New Mexico

    Science.gov (United States)

    Carol Raish

    1996-01-01

    The entrance of the Spanish into what is now New Mexico in the 1500s permanently altered aboriginal land use and subsistence patterns by the introduction of domesticated animals such as horses, cattle. sheep, goats, and pigs. During the Spanish Colonial and Mexican periods, both the Puebloan groups and the Hispanic settlers practiced mixed farming featuring small...

  3. THE DEMAND FOR PRIVATE PROPERTY RIGHTS: LAND TITLING, CREDIT, AND AGRICULTURAL PRODUCTIVITY IN MEXICO

    OpenAIRE

    Johnson, Nancy L.

    1998-01-01

    Land titles can increase agricultural productivity by increasing access to collateralized credit. However, increased credit use depends on the assumption that farmers face asset-based credit rationing. This assumption is tested using data from Mexico's voluntary land titling program. The results do not support the existence of widespread credit rationing.

  4. Integrating climate change in transportation and land use scenario planning : an example from central New Mexico

    Science.gov (United States)

    2015-04-01

    The Central New Mexico Climate Change Scenario Planning Project, an Interagency Transportation, Land Use, and Climate Change Initiative, utilized a scenario planning process to develop a multiagency transportation- and land use-focused development st...

  5. Modeling of earth fissures caused by land subsidence due to groundwater withdrawal

    Directory of Open Access Journals (Sweden)

    B. B. Panda

    2015-11-01

    Full Text Available Land subsidence and earth fissures are phenomena related to groundwater withdrawal in a sedimentary basin. If the rock basement or basin lithology is irregular, both vertical and horizontal displacements can be induced due to differential settlement and tensile stresses appearing in the soil mass. If the differential settlement is of sufficient magnitude, earth fissuring can occur within tensile zones. The magnitudes of compaction and fissure geometry are closely related to the thickness and skeletal compressibility of fine-grained sediments within the aquifer system. Land subsidence and earth fissuring were modeled by employing a two-dimensional (2-D coupled seepage and stress-strain finite element analysis. The basin bedrock geometry, lithological variation, measurements of surface displacements, and changes in hydraulic head were the critical input parameter for the subsidence modeling. Simulation results indicate that strain had exceeded the approximate threshold for fissure formation of 0.02 to 0.06 % in the area of the identified fissures. The numerical model was used to predict future subsidence and potential earth fissures for flood control structures within the metro Phoenix area.

  6. The Preservation of the Village: New Mexico's Hispanics and the New Deal. New Mexico Land Grant Series.

    Science.gov (United States)

    Forrest, Suzanne

    This volume, fourth in a series, is devoted to a study of the depression years of the 1930s, a crucial period in the history of the Hispanic land-grant-villages. It places northern New Mexico in a broad regional and national context, examining the major currents of social and political thought in American society that influenced Hispanic New Deal…

  7. Mexico.

    Science.gov (United States)

    Semaan, Leslie

    The text explores Mexico's history, geography, art, religion, and lifestyles in the context of its complex economy. The text focuses on Mexico's economy and reasons for its current situation. Part I of this teaching unit includes: Teacher Overview, Why Study Mexico, Mexico Fact Sheet, Map of Mexico, the Land and Climate, History, Government,…

  8. Excerpt from The Red Land to the South: American Indian Writers and Indigenous Mexico

    Directory of Open Access Journals (Sweden)

    James H. Cox

    2013-09-01

    Full Text Available Excerpted from James H. Cox, The Red Land to the South: American Indian Writers and Indigenous Mexico (Minneapolis: University of Minnesota Press, 2012.Reprinted with permission from University of Minnesota Press.

  9. Effects of different land use on soil chemical properties, decomposition rate and earthworm communities in tropical Mexico

    NARCIS (Netherlands)

    Geissen, V.; Peña-Peña, K.; Huerta, E.

    2009-01-01

    The effects of land use on soil chemical properties were evaluated, and earthworm communities and the decomposition rate of three typical land use systems in tropical Mexico, namely banana plantations (B), agroforestry systems (AF) and a successional forest (S) were compared. The study was carried

  10. Generating a National Land Cover Dataset for Mexico at 30m Spatial Resolution in the Framework of the NALCMS Project.

    Science.gov (United States)

    Llamas, R. M.; Colditz, R. R.; Ressl, R.; Jurado Cruz, D. A.; Argumedo, J.; Victoria, A.; Meneses, C.

    2017-12-01

    The North American Land Change Monitoring System (NALCMS) is a tri-national initiative for mapping land cover across Mexico, United States and Canada, integrating efforts of institutions from the three countries. At the continental scale the group released land cover and change maps derived from MODIS image mosaics at 250m spatial resolution for 2005 and 2010. Current efforts are based on 30m Landsat images for 2010 ± 1 year. Each country uses its own mapping approach and sources for ancillary data, while ensuring that maps are produced in a coherent fashion across the continent. This paper presents the methodology and final land cover map of Mexico for the year 2010 that was later integrated into a continental map. The principal input for Mexico was the Monitoring Activity Data for Mexico (MAD-MEX) land cover map (version 4.3), derived from all available mostly cloud-free images for the year 2010. A total of 35 classes were regrouped to 15 classes of the NALCMS legend present in Mexico. Next, various issues of the automatically generated MAD-MEX land cover mosaic were corrected, such as: filling areas of no data due no cloud-free observation or gaps in Landsat 7 ETM+ images, filling inland water bodies which were left unclassified due to masking issues, relabeling isolated unclassified of falsely classified pixels, structural mislabeling due to data gaps, reclassifying areas of adjacent scenes with significant class disagreements and correcting obvious misclassifications, mostly of water and urban areas. In a second step minor missing areas and rare class snow and ice were digitized and a road network was added. A product such as NALCMS land cover map at 30m for North America is an unprecedented effort and will be without doubt an important source of information for many users around the world who need coherent land cover data over a continental domain as an input for a wide variety of environmental studies. The product release to the general public is expected

  11. Climate change effects on central New Mexico's land use, transportation system and key natural resources : task 1.1 memo.

    Science.gov (United States)

    2014-12-01

    This report summarizes potential climate change effects on the availability of water, land use, transportation infrastructure, and key natural resources in central New Mexico. This work is being done as part of the Interagency Transportation, Land Us...

  12. Mass movement processes triggered by land subsidence in Iztapalapa, the eastern part of Mexico City

    Directory of Open Access Journals (Sweden)

    M. González-Hernández

    2015-11-01

    Full Text Available Geological and structural conditions in the Basin of Mexico coupled with natural and anthropogenic factors, such as groundwater exploitation, provokes land subsidence and differential deformation. The study area is located in to the north of Iztapalapa, a municipality within Mexico City, in a site called "El Eden" with irregular topography. Where volcanic sequences overlie the lacustrine deposits of clays and silts and show displacements by the action of gravity. The displacement zone was delimited at the top of the slope by the formation of circular tensile fractures with stair -shaped geometries. At the base of the slope, compressive processes damaged housing, sidewalks and inclined light poles and trees. A NW-SE system of fractures was identified in which displacement velocities vary from a few millimeters to several centimeters per year. Which affects urban facilities. In this work a conceptual model of deformation is presented that integrates the geological and mechanical factors leading to landslide and land subsidence. A geophysical survey leads to evidence of how land subsidence processes increase the sliding slope.

  13. Using Food Flow Data to Assess Sustainability: Land Use Displacement and Regional Decoupling in Quintana Roo, Mexico

    Directory of Open Access Journals (Sweden)

    Marco Millones

    2016-11-01

    Full Text Available Food flow data provide unique insights into the debates surrounding the sustainability of land based production and consumption at multiple scales. Trade flows disguise the spatial correspondence of production and consumption and make their connection to land difficult. Two key components of this spatial disjuncture are land use displacement and economic regional decoupling. By displacing the environmental impact associated with food production from one region to another, environmental trajectories can falsely appear to be sustainable at a particular site or scale. When regional coupling is strong, peripheral areas where land based production occurs are strongly linked and proximate to consumption centers, and the environmental impact of production activities is visible. When food flows occur over longer distances, regional coupling weakens, and environmental impact is frequently overlooked. In this study, we present an analysis of a locally collected food flow dataset containing agricultural and livestock products transported to and from counties in Quintana Roo (QRoo. QRoo is an extensively forested border state in southeast Mexico, which was fully colonized by the state and non-native settlers only in the last century and now is home to some of the major tourist destinations. To approximate land displacement and regional decoupling, we decompose flows to and from QRoo by (1 direction; (2 product types and; (3 scale. Results indicate that QRoo is predominantly a consumer state: incoming flows outnumber outgoing flows by a factor of six, while exports are few, specialized, and with varied geographic reach (Yucatan, south and central Mexico, USA. Imports come predominantly from central Mexico. Local production in QRoo accounts for a small portion of its total consumption. In combining both subsets of agricultural and livestock products, we found that in most years, land consumption requirements were above 100% of the available land not under

  14. Waste Isolation Pilot Plant, Land Management Plan

    International Nuclear Information System (INIS)

    1993-01-01

    To reflect the requirement of section 4 of the Wastes Isolation Pilot Plant Land Withdrawal Act (the Act) (Public Law 102-579), this land management plan has been written for the withdrawal area consistent with the Federal Land Policy and Management Act of 1976. The objective of this document, per the Act, is to describe the plan for the use of the withdrawn land until the end of the decommissioning phase. The plan identifies resource values within the withdrawal area and promotes the concept of multiple-use management. The plan also provides opportunity for participation in the land use planning process by the public and local, State, and Federal agencies. Chapter 1, Introduction, provides the reader with the purpose of this land management plan as well as an overview of the Waste Isolation Pilot Plant. Chapter 2, Affected Environment, is a brief description of the existing resources within the withdrawal area. Chapter 3, Management Objectives and Planned Actions, describes the land management objectives and actions taken to accomplish these objectives

  15. Waste Isolation Pilot Plant, Land Management Plan

    Energy Technology Data Exchange (ETDEWEB)

    1993-12-01

    To reflect the requirement of section 4 of the Wastes Isolation Pilot Plant Land Withdrawal Act (the Act) (Public Law 102-579), this land management plan has been written for the withdrawal area consistent with the Federal Land Policy and Management Act of 1976. The objective of this document, per the Act, is to describe the plan for the use of the withdrawn land until the end of the decommissioning phase. The plan identifies resource values within the withdrawal area and promotes the concept of multiple-use management. The plan also provides opportunity for participation in the land use planning process by the public and local, State, and Federal agencies. Chapter 1, Introduction, provides the reader with the purpose of this land management plan as well as an overview of the Waste Isolation Pilot Plant. Chapter 2, Affected Environment, is a brief description of the existing resources within the withdrawal area. Chapter 3, Management Objectives and Planned Actions, describes the land management objectives and actions taken to accomplish these objectives.

  16. Bureau of Land Management Land Grant Boundaries

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This data has been collected by the U.S. Bureau of Land Management (BLM) in New Mexico at the New Mexico State Office. The initial data source is the statewide...

  17. The legacy of social conflicts over property rights in rural Brazil and Mexico : Current land struggles in historical perspective

    NARCIS (Netherlands)

    Vergara-Camus, Leandro

    2012-01-01

    This article proposes an approach to the agrarian question that focuses on the establishment of absolute private property rights over land in Brazil and Mexico. The author argues that current land struggles are conditioned by the property regimes inherited from past struggles. The author examines

  18. Spatial and temporal land cover changes in Terminos Lagoon Reserve, Mexico.

    Science.gov (United States)

    Soto-Galera, Ernesto; Piera, Jaume; López, Pilar

    2010-06-01

    Terminos Lagoon ecosystem is the largest fluvial-lagoon estuarine system in the country and one of the most important reserves of coastal flora and fauna in Mexico. Since the seventies, part of the main infrastructure for country's oil extraction is located in this area. Its high biodiversity has motivated different type of studies including deforestation processes and land use planning. In this work we used satellite image analysis to determine land cover changes in the area from 1974 to 2001. Our results indicate that tropical forest and mangroves presented the most extensive losses in its coverage. In contrast, urban areas and induced grassland increased considerably. In 2001 more than half of the ecosystem area showed changes from its original land cover, and a third part of it was deteriorated. The main causes of deforestation were both the increase in grassland and the growth of urban areas. However, deforestation was attenuated by natural reforestation and plant canopy recovery. We conclude that the introduction of cattle and urban development were the main causes for the land cover changes; however, the oil industry activity located in the ecosystem, has promoted indirectly to urban growth and rancher boom.

  19. TREATY OF GUADALUPE HIDALGO: Definition and List of Community Land Grants in New Mexico. Exposure Draft

    National Research Council Canada - National Science Library

    2001-01-01

    .... In New Mexico, these land grants fulfilled several purposes: to encourage settlement, reward patrons of the Spanish government, and create a buffer zone to separate hostile Native American tribes from the more populated regions of New Spain...

  20. Bureau of Land Management Surface Land Ownership (2014)

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — These data were collected by the U.S. Bureau of Land Management (BLM) in New Mexico at both the New Mexico State Office and at the various field offices. This...

  1. Bureau of Land Management Surface Land Ownership (2012)

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — These data was collected by the U.S. Bureau of Land Management (BLM) in New Mexico at both the New Mexico State Office and at the various field offices. This dataset...

  2. Tularosa, NM 1:250,000 Quad USGS Land Use/Land Cover, 1986

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This dataset contains boundaries for land use and land cover polygons in New Mexico at a scale of 1:250,000. It is in a vector digital data structure. The source...

  3. Gallup, NM AZ 1:250,000 Quad USGS Land Use/Land Cover, 1986

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This dataset contains boundaries for land use and land cover polygons in New Mexico at a scale of 1:250,000. It is in a vector digital data structure. The source...

  4. Santa Fe, NM 1:250,000 Quad USGS Land Use/Land Cover, 1986

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This dataset contains boundaries for land use and land cover polygons in New Mexico at a scale of 1:250,000. It is in a vector digital data structure. The source...

  5. 76 FR 12992 - Notice of Public Meeting for Proposed Withdrawal

    Science.gov (United States)

    2011-03-09

    ... DEPARTMENT OF THE INTERIOR Bureau of Land Management [LLCAC09000 L14300000.ET0000; CACA 51408] Notice of Public Meeting for Proposed Withdrawal AGENCY: Bureau of Land Management, Interior. ACTION: Notice of public meeting. SUMMARY: A Notice was published in the Federal Register on August 3, 2010...

  6. El Paso, TX NM 1:250,000 Quad USGS Land Use/Land Cover, 1986

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This dataset contains boundaries for land use and land cover polygons in New Mexico at a scale of 1:250,000. It is in a vector digital data structure. The source...

  7. Las Cruces, NM TX 1:250,000 Quad USGS Land Use/Land Cover, 1986

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This dataset contains boundaries for land use and land cover polygons in New Mexico at a scale of 1:250,000. It is in a vector digital data structure. The source...

  8. Saint Johns, AZ NM 1:250,000 Quad USGS Land Use/Land Cover, 1986

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This dataset contains boundaries for land use and land cover polygons in New Mexico at a scale of 1:250,000. It is in a vector digital data structure. The source...

  9. Silver City, NM AZ 1:250,000 Quad USGS Land Use/Land Cover, 1986

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This dataset contains boundaries for land use and land cover polygons in New Mexico at a scale of 1:250,000. It is in a vector digital data structure. The source...

  10. 75 FR 29577 - Notice of Filing of Plats of Survey, New Mexico

    Science.gov (United States)

    2010-05-26

    ... of Plats of Survey, New Mexico AGENCY: Bureau of Land Management, Interior. ACTION: Notice of filing... in the New Mexico State Office, Bureau of Land Management (BLM), Santa Fe, New Mexico, thirty (30... available for inspection in the New Mexico State Office, Bureau of Land Management, 301 Dinosaur Trail...

  11. 76 FR 15994 - Notice of Filing of plats of survey, New Mexico

    Science.gov (United States)

    2011-03-22

    ... of plats of survey, New Mexico AGENCY: Bureau of Land Management, Interior. ACTION: Notice of filing... in the New Mexico State Office, Bureau of Land Management, Santa Fe, New Mexico, thirty (30) calendar... for inspection in the New Mexico State Office, Bureau of Land Management, 301 Dinosaur Trail, Santa Fe...

  12. 76 FR 4372 - Notice of Filing of Plats of Survey, New Mexico

    Science.gov (United States)

    2011-01-25

    ... of Plats of Survey, New Mexico AGENCY: Bureau of Land Management, Interior. ACTION: Notice of filing... in the New Mexico State Office, Bureau of Land Management, Santa Fe, New Mexico, thirty (30) calendar... for inspection in the New Mexico State Office, Bureau of Land Management, 301 Dinosaur Trail, Santa Fe...

  13. Tenure, tourism and timber in Quintana Roo, Mexico: Land tenure changes in forest Ejidos after agrarian reforms

    Directory of Open Access Journals (Sweden)

    James A. Barsimantov

    2009-09-01

    Full Text Available We present and apply an analytical framework for understanding land tenure change in the wake of radical land policy modifications in Mexico’s communal tenure system. We posit that the changes in land tenure vary as a result of a complex interplay of drivers external and internal to the land tenure unit. Using interview and socio-economic data, we apply this framework to six ejidos in Quintana Roo, Mexico in order to understand the extent to which these ejidos have shifted towards private individual property as promoted in the 1992 amendment of Article 27 of the Mexican Constitution. In our case study ejidos, we conclude that external factors, including community forestry, tourism, and urbanization, have synergized with factors internal to the ejido, such as ethnicity, livelihood strategies, migration, and attitudes, leading to different trajectories in land tenure arrangements.

  14. Shiprock, AZ NM CO UT 1:250,000 Quad USGS Land Use/Land Cover, 1986

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This dataset contains boundaries for land use and land cover polygons in New Mexico at a scale of 1:250,000. It is in a vector digital data structure. The source...

  15. Modelling ground rupture due to groundwater withdrawal: applications to test cases in China and Mexico

    Science.gov (United States)

    Franceschini, A.; Teatini, P.; Janna, C.; Ferronato, M.; Gambolati, G.; Ye, S.; Carreón-Freyre, D.

    2015-11-01

    The stress variation induced by aquifer overdraft in sedimentary basins with shallow bedrock may cause rupture in the form of pre-existing fault activation or earth fissure generation. The process is causing major detrimental effects on a many areas in China and Mexico. Ruptures yield discontinuity in both displacement and stress field that classic continuous finite element (FE) models cannot address. Interface finite elements (IE), typically used in contact mechanics, may be of great help and are implemented herein to simulate the fault geomechanical behaviour. Two main approaches, i.e. Penalty and Lagrangian, are developed to enforce the contact condition on the element interface. The incorporation of IE incorporation into a three-dimensional (3-D) FE geomechanical simulator shows that the Lagrangian approach is numerically more robust and stable than the Penalty, thus providing more reliable solutions. Furthermore, the use of a Newton-Raphson scheme to deal with the non-linear elasto-plastic fault behaviour allows for quadratic convergence. The FE - IE model is applied to investigate the likely ground rupture in realistic 3-D geologic settings. The case studies are representative of the City of Wuxi in the Jiangsu Province (China), and of the City of Queretaro, Mexico, where significant land subsidence has been accompanied by the generation of several earth fissures jeopardizing the stability and integrity of the overland structures and infrastructure.

  16. Application of InSAR and Gravimetry for Land Subsidence Hazard Zoning in Aguascalientes, Mexico

    OpenAIRE

    Pacheco-Martínez, Jesús; Cabral-Cano, Enrique; Wdowinski, Shimon; Hernández-Marín, Martín; Ortiz-Lozano, José; Zermeño-de-León, Mario

    2015-01-01

    In this work we present an application of InSAR and gravimetric surveys for risk management related to land subsidence and surface ground faulting generation. A subsidence velocity map derived from the 2007–2011 ALOS SAR imagery and a sediment thicknesses map obtained from the inversion of gravimetric data were integrated with a surface fault map to produce a subsidence hazard zoning in the city of Aguascalientes, Mexico. The resulting zoning is presented together with specific recommendation...

  17. 75 FR 3917 - Notice of Partial Cancellation of Proposed Withdrawal; California

    Science.gov (United States)

    2010-01-25

    ... the transfer of jurisdiction and the withdrawal of approximately 365,906 acres of public land and... land laws, including surface entry, mining, mineral leasing, and the Materials Act of 1947. This notice... laws, including the mining laws, and the operation of the mineral leasing laws and the Materials Act of...

  18. Assessing land use/cover changes: a nationwide multidate spatial database for Mexico

    Science.gov (United States)

    Mas, Jean-François; Velázquez, Alejandro; Díaz-Gallegos, José Reyes; Mayorga-Saucedo, Rafael; Alcántara, Camilo; Bocco, Gerardo; Castro, Rutilio; Fernández, Tania; Pérez-Vega, Azucena

    2004-10-01

    A nationwide multidate GIS database was generated in order to carry out the quantification and spatial characterization of land use/cover changes (LUCC) in Mexico. Existing cartography on land use/cover at a 1:250,000 scale was revised to select compatible inputs regarding the scale, the classification scheme and the mapping method. Digital maps from three different dates (the late 1970s, 1993 and 2000) were revised, evaluated, corrected and integrated into a GIS database. In order to improve the reliability of the database, an attempt was made to assess the accuracy of the digitalisation procedure and to detect and correct unlikely changes due to thematic errors in the maps. Digital maps were overlaid in order to generate LUCC maps, transition matrices and to calculate rates of conversion. Based upon this database, rates of deforestation between 1976 and 2000 were evaluated as 0.25 and 0.76% per year for temperate and tropical forests, respectively.

  19. 76 FR 52012 - Notice of Filing of Plats of Survey, New Mexico

    Science.gov (United States)

    2011-08-19

    ... Filing of Plats of Survey, New Mexico AGENCY: Bureau of Land Management, Interior. ACTION: Notice of... filed in the New Mexico State Office, Bureau of Land Management, Santa Fe, New Mexico, thirty (30) calendar days from the date of this publication. SUPPLEMENTARY INFORMATION: New Mexico Principal Meridian...

  20. Satellite-derived land surface parameters for mesoscale modelling of the Mexico City basin

    Directory of Open Access Journals (Sweden)

    B. de Foy

    2006-01-01

    Full Text Available Mesoscale meteorological modelling is an important tool to help understand air pollution and heat island effects in urban areas. Accurate wind simulations are difficult to obtain in areas of weak synoptic forcing. Local factors have a dominant role in the circulation and include land surface parameters and their interaction with the atmosphere. This paper examines an episode during the MCMA-2003 field campaign held in the Mexico City Metropolitan Area (MCMA in April of 2003. Because the episode has weak synoptic forcing, there is the potential for the surface heat budget to influence the local meteorology. High resolution satellite observations are used to specify the land use, vegetation fraction, albedo and surface temperature in the MM5 model. Making use of these readily available data leads to improved meteorological simulations in the MCMA, both for the wind circulation patterns and the urban heat island. Replacing values previously obtained from land-use tables with actual measurements removes the number of unknowns in the model and increases the accuracy of the energy budget. In addition to improving the understanding of local meteorology, this sets the stage for the use of advanced urban modules.

  1. Assessment of land use and land cover change in Tecolutla River Basin, Veracruz, Mexico; during the period 1994-2010

    Directory of Open Access Journals (Sweden)

    Ana Karen Osuna-Osuna

    2015-04-01

    Full Text Available Studies related to changes in vegetation and land use cover have gained importance in environmental research, as they allow for the assessment of time-space trends in deforestation and environmental degradation processes, especially as caused by human activity. In this context, the main goal of this study was to evaluate the impact of human activity in the basin of the Tecolutla River, in Veracruz, Mexico during a 16-year period. Landsat satellite images were used for the years 1994 and 2010, distinguishing nine land use coverage classes: rainforest, forest, agricultural land, water, disturbed vegetation, urban settlements, grasslands, citrus crops and shrubs. Thematic maps were validated, yielding overall accuracies greater than 92% and Kappa coefficients of 0.89 and 0.91 for the 1994 and 2010 classifications, respectively. Analysis of the transition matrix revealed a trend of increasing areas related to human activity (agriculture and urban use showing percentage changes of 28% and 67% within 16 years, respectively. Consequently, a decrease (-1.1% per year in areas with natural cover, specifically forest and jungle, was observed. Similar findings were reported in works done at national and state levels, where the transition of natural cover by the increasing of anthropogenic activities has been proven. The results of this study are useful for future environmental development planning, land management planning and planning strategies for the conservation of the natural resources in the basin.

  2. Public Land Survey System - Sections on USDA Forest Service Lands

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This feature class depicts the boundaries of Land Survey features called sections, defined by the Public Lands Survey System Grid. Normally, 36 sections make up a...

  3. 76 FR 67473 - Notice of Proposed Withdrawal, Transfer of Jurisdiction, and Notice of Public Meeting; California

    Science.gov (United States)

    2011-11-01

    ... DEPARTMENT OF THE INTERIOR Bureau of Land Management [CACA 43949, LLCA930000, L14300000.ET0000] Notice of Proposed Withdrawal, Transfer of Jurisdiction, and Notice of Public Meeting; California AGENCY: Bureau of Land Management, Interior. ACTION: Notice; Correction. SUMMARY: The Bureau of Land Management...

  4. 75 FR 70288 - Notice of Proposed Withdrawal, Transfer of Jurisdiction, and Notice of Public Meeting; California

    Science.gov (United States)

    2010-11-17

    ... DEPARTMENT OF THE INTERIOR Bureau of Land Management [LLCAD06000-L14300000-ET0000; CACA 43949] Notice of Proposed Withdrawal, Transfer of Jurisdiction, and Notice of Public Meeting; California AGENCY: Bureau of Land Management, Interior. ACTION: Correction. SUMMARY: The Bureau of Land Management published...

  5. Influence of climate and land use on historical surface fires in pine-oak forests, Sierra Madre Occidental, Mexico

    Science.gov (United States)

    Emily K. Heyerdahl; Ernesto Alvarado

    2003-01-01

    The rugged mountains of the Sierra Madre Occidental, in north-central Mexico, support a mosaic of diverse ecosystems. Of these, the high-elevation, temperate pine-oak forests are ecologically significant for their extensiveness and biodiversity. They cover nearly half the land area in the states of Durango and Chihuahua (42%), and comprise a similar percentage of the...

  6. 78 FR 51741 - Notice of Application for Withdrawal and Opportunity for Public Meeting; California

    Science.gov (United States)

    2013-08-21

    ... DEPARTMENT OF THE INTERIOR Bureau of Land Management [LLCAN06000-L14300000-ET0000/CACA 54303] Notice of Application for Withdrawal and Opportunity for Public Meeting; California AGENCY: Bureau of Land Management, Interior. ACTION: Notice. SUMMARY: The United States Forest Service (USFS) filed an...

  7. Agricultural Land Use Change after NAFTA in Central West Mexico

    Directory of Open Access Journals (Sweden)

    Quetzalcóatl Orozco-Ramírez

    2017-10-01

    Full Text Available It has been suggested that agricultural land use change and modernization in agricultural production techniques are related to the loss of crop diversity. Two processes contribute to this loss; first is the replacement of landraces by modern varieties, and second is the abandonment of traditional crops in favor of cash crops. We studied the expression of these processes in a region that is both an agro-biodiversity and cultural center and one of the most significant fruit exporters of Mexico. We analyzed agricultural change based on the transformation of cropping areas and the primary crops’ locations in Michoacán state. We examined the crop-harvested area statistics from 1950 to 2015, and identified 23 crops as the most important in terms of harvested area and monetary value. After NAFTA (North American Free Trade Agreement, harvested area for nine crops changed significantly: seven crops increased, and two decreased. Positive trends were observed for commercial fruits oriented to export markets, and negative trends were observed for traditional crops. These crops, such as beans and maize, are important for food security. Additionally, we analyzed how these land-use and agricultural changes overlap in zones of maize planted-area change. Using a maize-race collection database, we identified three native maize races that could be at risk due to the abandonment of maize in favor of commercial crops.

  8. Land Change Regimes and the Evolution of the Maize-Cattle Complex in Neoliberal Mexico

    Directory of Open Access Journals (Sweden)

    Yankuic Galvan-Miyoshi

    2015-08-01

    Full Text Available How globalization impacts native land cover has become an important issue in studies addressing environmental change, which draw explicit attention to processes of cause and effect operating over significant distances. The literature shows that globalization constitutes an important underlying driver of both deforestation and forest transition via demographic and economic phenomena such as migration and remittance flows. Yet, little is known about how global forces mold the spatial structure of agro-commodity production and how this impacts the balance of forces affecting land change at the meso-scale, within the boundaries of the nation-state. The research presented here fills this gap by examining production networks for Mexico, a large OECD country with complex land change dynamics that has recently experienced a dramatic opening to the world economy. Specifically, we consider how maize and beef commodity chains evolved over the past few decades into a highly interdependent maize-cattle complex, and suggest linkages to patterns of land change at the national scale. Using land cover maps for 1993, 2002, and 2012, at the national scale, governmental statistics and datasets, interviews with key informants, and field observations the article provides an analysis of the impact of neoliberal reforms on the changing geography of beef and maize production, and argues that this process underlies the evolution of Mexico’s land change regime, both before and after the NAFTA reforms. As such, the article presents an account, and a case for further research on the topic of how teleconnections are constituted by spatially-extensive food production networks.

  9. Reliability analysis of land pipelines for hydrocarbons transportation in Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Leon, D.; Cortes, C. [Inst. Mexicano del Petroleo (Mexico)

    2004-07-01

    The reliability of a land pipeline operated by PEMEX in Mexico was estimated under a range of failure modes. Reliability and safety were evaluated in terms of the pipeline's internal pressure, bending, fracture toughness and its tension failure mode conditions. Loading conditions were applied individually, while bending and tension loads were applied in a combined fashion. The mechanical properties of the steel were also considered along with the degradation effect of internal corrosion resulting from the type of product being transported. A set of internal pressures and mechanical properties were generated randomly using Monte Carlo simulation. Commercial software was used to obtain the pipeline response under each modeled condition. The response analysis was based on the nonlinear finite element method involving a calculation of maximum stresses and stress concentration factors under conditions of corrosion and no corrosion. The margin between maximum stresses due to internal pressure, tension and bending was evaluated along with the margin between stress concentration factor and fracture initiation toughness. The study showed that internal pressure, stress concentration and tension-bending were the critical failure modes. It was suggested that more research should be conducted to improve the modeling of the deteriorating effects of corrosion and to adjust the probability distribution for fracture toughness and the length/depth defect ratio. The consideration of welding geometries along with features of marine pipelines and pipeline products would help to generalize the study to facilitate the creation of codes for the construction, design, inspection and maintenance of pipelines in Mexico. 7 refs., 1 tab., 14 figs.

  10. Impacts of impervious cover, water withdrawals, and climate change on river flows in the conterminous US

    Directory of Open Access Journals (Sweden)

    P. V. Caldwell

    2012-08-01

    Full Text Available Rivers are essential to aquatic ecosystem and societal sustainability, but are increasingly impacted by water withdrawals, land-use change, and climate change. The relative and cumulative effects of these stressors on continental river flows are relatively unknown. In this study, we used an integrated water balance and flow routing model to evaluate the impacts of impervious cover and water withdrawal on river flow across the conterminous US at the 8-digit Hydrologic Unit Code (HUC watershed scale. We then estimated the impacts of projected change in withdrawals, impervious cover, and climate under the B1 "Low" and A2 "High" emission scenarios on river flows by 2060. Our results suggest that compared to no impervious cover, 2010 levels of impervious cover increased river flows by 9.9% on average with larger impacts in and downstream of major metropolitan areas. In contrast, compared to no water withdrawals, 2005 withdrawals decreased river flows by 1.4% on average with larger impacts in heavily irrigated arid regions of Western US. By 2060, impacts of climate change were predicted to overwhelm the potential gain in river flow due to future changes in impervious cover and add to the potential reduction in river flows from withdrawals, decreasing mean annual river flows from 2010 levels by 16% on average. However, increases in impervious cover by 2060 may offset the impact of climate change during the growing season in some watersheds. Large water withdrawals will aggravate the predicted impact of climate change on river flows, particularly in the Western US. Predicted ecohydrological impacts of land cover, water withdrawal, and climate change will likely include alteration of the terrestrial water balance, stream channel habitat, riparian and aquatic community structure in snow-dominated basins, and fish and mussel extirpations in heavily impacted watersheds. These changes may also require new infrastructure to support increasing anthropogenic

  11. Bureau of Land Management Range Allotments

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This data has been collected by the U.S. Bureau of Land Management (BLM) in New Mexico at both the New Mexico State Office and the various field offices. Collection...

  12. 77 FR 53906 - Notice of Proposed Withdrawal and Opportunity for Public Meeting; California

    Science.gov (United States)

    2012-09-04

    ... from mining while various studies and analyses are made to support a final decision on the withdrawal... acres of public lands from location and entry under the United States mining laws for a period of 20..., the lands will be segregated from location and entry under the United States mining laws, but not from...

  13. Land subsidence and recovery in the Albuquerque Basin, New Mexico, 1993–2014

    Science.gov (United States)

    Driscoll, Jessica M.; Brandt, Justin T.

    2017-08-14

    inconsistent land-surface elevation changes over the Albuquerque Basin, likely because of the lack of significant change and the complexity of subsurface stratigraphy in addition to the spatial and temporal heterogeneity of groundwater withdrawals over the study period. Results from the InSAR analysis show areas of land-surface elevation increase after 2008, which could be attributed to elastic recovery of the aquifer system. The spatial extent to which elastic recovery of the aquifer system has resulted in recovery of land-surface elevation is limited to the in-situ measurements at the extensometer. Examination of spatially distributed InSAR data relative to limited spatial extent of the complex heterogeneity subsurface stratigraphy may explain some of the heterogeneity of land-surface elevation changes over this study period.

  14. Household Land Management and Biodiversity: Secondary Succession in a Forest-Agriculture Mosaic in Southern Mexico

    Directory of Open Access Journals (Sweden)

    Rinku Roy Chowdhury

    2007-12-01

    Full Text Available This study evaluates anthropogenic and ecological dimensions of secondary forest succession in Mexico's southern Yucatán peninsular region, a hotspot of biodiversity and tropical deforestation. Secondary succession in particular constitutes an ecologically and economically important process, driven by and strongly influencing land management and local ecosystem structure and dynamics. As agents of local land management, smallholding farmers in communal, i.e., ejido lands affect rates of forest change, biodiversity, and sustainability within and beyond their land parcels. This research uses household surveys and land parcel mapping in two ejidos located along the buffer of the Calakmul Biosphere Reserve to analyze how household socioeconomics and policy institutions drive allocations to successional forests in traditional crop fallows and in enriched fallows. Results indicate that household tenancy, livestock holdings, labor-consumer ratios, and receipts of agricultural subsidies are the strongest determinants of traditional fallow areas. Whereas the latter two factors also influence enriched successions, local agroforestry and reforestation programs were the strongest drivers of fallow enrichment. Additionally, the study conducts field vegetation sampling in a nested design within traditional and enriched fallow sites to comparatively assess biodiversity consequences of fallow management. Although enriched fallows display greater species richness in 10x10 m plots and 2x2 m quadrats, plot-scale data reveal no significant differences in Shannon-Wiener or Simpson's diversity indices. Traditional fallows display greater species heterogeneity at the quadrat scale, however, indicating a complex relationship of diversity to fallow management over time. The article discusses the implications of the social and ecological analyses for land change research and conservation policies.

  15. Bureau of Land Management Wilderness Areas

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This dataset is meant to depict wilderness areas within the state of New Mexico managed by the Bureau of Land Management These wilderness areas are officially...

  16. 40 CFR 81.421 - New Mexico.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 17 2010-07-01 2010-07-01 false New Mexico. 81.421 Section 81.421 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF... Visibility Is an Important Value § 81.421 New Mexico. Area name Acreage Public Law establishing Federal land...

  17. Identifying the hotspots of non-renewable water use using HiGW-MAT: A new land surface model coupled with human interventions and ground water reservoir

    Science.gov (United States)

    Oki, T.; Pokhrel, Y. N.; Yeh, P. J.; Koirala, S.; Kanae, S.; Hanasaki, N.

    2011-12-01

    The real hydrological cycles on the Earth are not natural anymore. Global hydrological model simulations of the water cycle and available water resources should have an ability to consider the effects of human interventions on hydrological cycles. Anthropogenic activity modules (Hanasaki et al., 2008), such as reservoir operation, crop growth and water demand in crop lands, and environmental flows, were incorporated into a land surface model called MATSIRO (Takata et al., 2003), to form a new model, MAT-HI (Pokhrel et al., 2011). Total terrestrial water storages (TWS) in large river basins were estimated using the new model by off-line simulation, and compared with the TWS observed by GRACE for 2002-2007. The results showed MAT-HI has an advantage estimating TWS particularly in arid river basins compared with H08 (Hanasaki et al., 2008). MAT-HI was further coupled with a module representing the ground water level fluctuations (Yeh et al., 2005), and consists a new land surface scheme HiGW-MAT (Human Intervention and Ground Water coupled MATSIRO). HiGW-MAT is also associated with a scheme tracing the origin and flow path with the consideration on the sources of water withdrawal from stream flow, medium-size reservoirs and nonrenewable groundwater in addition to precipitation to croplands enabled the assessment of the origin of water producing major crops as Hanasaki et al. (2010). Areas highly dependent on nonrenewable groundwater are detected in the Pakistan, Bangladesh, western part of India, north and western parts of China, some regions in the Arabian Peninsula and the western part of the United States through Mexico. Cumulative nonrenewable groundwater withdrawals estimated by the model are corresponding fairly well with the country statistics of total groundwater withdrawals. Ground water table depletions in large aquifers in US estimated by HiGW-MAT were compared with in-situ observational data, and the correspondences are very good. Mean global exploitation

  18. Assessing hydrologic impacts of future Land Change scenarios in the San Pedro River (U.S./Mexico)

    Science.gov (United States)

    Kepner, W. G.; Burns, S.; Sidman, G.; Levick, L.; Goodrich, D. C.; Guertin, P.; Yee, W.; Scianni, M.

    2012-12-01

    An approach was developed to characterize the hydrologic impacts of urban expansion through time for the San Pedro River, a watershed of immense international importance that straddles the U.S./Mexico border. Future urban growth is a key driving force altering local and regional hydrology and is represented by decadal changes in housing density maps from 2010 to 2100 derived from the Integrated Climate and Land-Use Scenarios (ICLUS) database. ICLUS developed future housing density maps by adapting the Intergovernmental Panel on Climate Change (IPCC) Special Report on Emissions Scenarios (SRES) social, economic, and demographic storylines to the conterminous United States. To characterize the hydrologic impacts of future growth, the housing density maps were reclassified to National Land Cover Database 2006 land cover classes and used to parameterize the Soil and Water Assessment Tool (SWAT) using the Automated Geospatial Watershed Assessment (AGWA) tool. The presentation will report 1) the methodology for adapting the ICLUS data for use in AGWA as an approach to evaluate basin-wide impacts of development on water-quantity and -quality, 2) initial results of the application of the methodology, and 3) discuss implications of the analysis.

  19. Mexico.

    Science.gov (United States)

    1993-01-01

    The background notes on Mexico provide text and recent statistical information on the geography, population, government, economy, and foreign relations, specifically the North American Free Trade Agreement with US. The 1992 population is estimated at 89 million of which 60% are mestizo (Indian-Spanish), 30% are American Indian, 9% are Caucasian, and 1% are other. 90% are Roman Catholic. There are 8 years of compulsory education. Infant mortality is 30/1000 live births. Life expectancy for males is 68 years and 76 years for females. The labor force is comprised of 30% in services, 24% in agriculture and fishing, 19% in manufacturing, 13% in commerce, 7% in construction, 4% in transportation and communication, and .4% in mining. There are 31 states and a federal district. Gross domestic product (GDP) per capita was $3200 in 1991. Military expenditures were .5% of GDP in 1991. The average inflation rate is 19%. Mexico City with 20 million is the largest urban center in the world. In recent years, the economy has been restructured with market oriented reforms; the result has been a growth of GDP of 3.6% in 1991 from 2% in 1987. Dependence on oil exports has decreased. There has been privatization and deregulation of state-owned companies. Subsidies to inefficient companies have been stopped. Tariff rates were reduced. The financial debt has been reduced and turned into a surplus of .8% in 1992. Mexico's foreign debt has been reduced from its high in 1987 of $107 billion. Agricultural reforms have been ongoing for 50 years. Land was redistributed, but standards of living and productivity have improved only slightly. Rural land tenure regulations have been changed, and other economic reforms are expected. Mexico engages in ad hoc international groups and is selective about membership in international organizations.

  20. 78 FR 44965 - Notice of Proposed Withdrawal Extension and Opportunity for Public Meeting for the Grays Lake...

    Science.gov (United States)

    2013-07-25

    .... 7130 transferred jurisdiction of 37.5 acres of public land withdrawn from settlement, sale, location, or entry under the public land laws, including the United States mining laws, from the U.S. Forest... INFORMATION: The withdrawal created by PLO No. 7130 (60 FR 16585 (1995)), which transferred jurisdiction of 37...

  1. Bureau of Land Management Federal Subsurface Mineral Ownership (2012)

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — These data were collected by the U.S. Bureau of Land Management (BLM) in New Mexico at both the New Mexico State Office and at the various field offices. This...

  2. Bureau of Land Management Wilderness Study Areas

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This dataset is meant to depict Wilderness Study Areas (WSA's), within the state of New Mexico, identified by the U.S. Bureau of Land Management (BLM) as having...

  3. 76 FR 33352 - Notice of Proposed Withdrawal and Opportunity for Public Meeting; California

    Science.gov (United States)

    2011-06-08

    ..., solar, and wind energy study areas for future renewable energy development. This notice temporarily... withdrawal is to protect and preserve geothermal, solar, and wind energy study areas for future renewable... lands while the BLM evaluates the area for renewable energy development, including geothermal leasing...

  4. Transfer and Transition: Interagency Coordination for Managing Public Lands at UMTRCA Title II Sites in Wyoming – 16614

    Energy Technology Data Exchange (ETDEWEB)

    Shafer, David S. [U.S. Dpartment of Energy, Office of Legacy Management; Vanek, Tim [U.S.Department of Energy, Office of Legacy Management; Ribeiro, Tracy [U.S. Department of Energy, Office of Legacy Management; Bahrke, Cheri [Navarro Research and Engineering

    2016-03-06

    By the end of fiscal year 2025, the U.S. Department of Energy (DOE) Office of Legacy Management (LM) is anticipating adding 17 sites remediated under Title II of the Uranium Mill Tailings Radiation Control Act (UMTRCA) to the current inventory of 90 sites that it manages. Among the new sites are ones where federal public lands occur within the proposed long-term care boundary, the boundary determined by the Nuclear Regulatory Commission and LM as necessary to maintain site protectiveness for the entombed uranium mill tailings and residual groundwater contamination. For these sites, public land withdrawals for land and minerals will need to be established. LM’s primary mission at UMTRCA sites is to protect the public and the environment from exposure to contamination at the sites. For the sites with public lands or federally controlled minerals that will be transferring to LM, the Office will apply to the Department of the Interior (DOI) Bureau of Land Management (BLM) for new, public land and mineral withdrawals. At most current LM UMTRCA sites that involved public lands and minerals, DOI granted DOE “full administrative jurisdiction” and permanent withdrawals. Hence, these withdrawals are, permanently, no longer subject to public land, mining, and mineral-leasing laws and regulations. LM is coordinating with DOI/BLM in Wyoming to permanently withdraw full and partial jurisdiction at future UMTRCA Title II sites in that state. This approach would allow LM to fully administer surface lands and minerals, where necessary, and DOI and LM to administer surface lands and leasable minerals where it would not jeopardize sites’ radiological safety and long-term public and environmental protection. This “shared-jurisdiction approach” will meet LM’s strategic goal of protecting human health and the environment but also allow BLM to fulfill their mission to “manage and conserve the lands under the mandate of multiple-use and sustained yield.” In addition, LM

  5. [An examination of the determinants of social withdrawal and affinity for social withdrawal].

    Science.gov (United States)

    Watanabe, Asami; Matsui, Yutaka; Takatsuka, Yusuke

    2010-12-01

    This study examined the determinants of social withdrawal using data from a survey by the Tokyo Metropolitan Government Office for Youth Affairs and Public Safety (2008). In addition, this study identified young people who showed an affinity for social withdrawal although they were not in a state of withdrawal, and examined the determinants of an affinity for social withdrawal. The results of stepwise discriminant analysis showed that factors such as social phobia, depression, violence, and emotional bonds with family differentiated between the general youth group and the social withdrawal group and the "affinity group". Social phobia, violence, and refusal to be interfered in self-decision making differentiated between the social withdrawal group and the "affinity group". This study shows that an "affinity group" should be cared as well as an actual withdrawal group.

  6. Potential for extending major land resource areas into northern Mexico

    Science.gov (United States)

    Roy S. Mann; Philip Heilman; Jeffry. Stone

    2013-01-01

    There is a significant history of cooperative efforts between Mexico and the United States on natural resource management issues. Mexico and the United States have jointly conducted research and developed range management technologies. Bringing these technologies together and improving technical communications are an ongoing process. This paper discusses a potential...

  7. Land cover changes in central Sonora Mexico

    Science.gov (United States)

    Diego Valdez-Zamudio; Alejandro Castellanos-Villegas; Stuart Marsh

    2000-01-01

    Remote sensing techniques have been demonstrated to be very effective tools to help detect, analyze, and evaluate land cover changes in natural areas of the world. Changes in land cover can generally be attributed to either natural or anthropogenic forces. Multitemporal satellite imagery and airborne videography were used to detect, analyze, and evaluate land cover...

  8. Treatment for amphetamine withdrawal.

    Science.gov (United States)

    Shoptaw, Steven J; Kao, Uyen; Heinzerling, Keith; Ling, Walter

    2009-04-15

    Few studies examined treatments for amphetamine withdrawal, although it is a common problem among amphetamine users. Its symptoms, in particular intense craving, may be a critical factor leading to relapse to amphetamine use. In clinical practice, medications for cocaine withdrawal are commonly used to manage amphetamine withdrawal although the pharmacodynamic and pharmacokinetic properties of these two illicit substances are different. To assess the effectiveness of pharmacological alone or in combination with psychosocial treatment for amphetamine withdrawals on discontinuation rates, global state, withdrawal symptoms, craving, and other outcomes. MEDLINE (1966 - 2008), CINAHL (1982 - 2008), PsycINFO (1806 - 2008), CENTRAL (Cochrane Library 2008 issue 2), references of obtained articles. All randomised controlled and clinical trials evaluating pharmacological and or psychosocial treatments (alone or combined) for people with amphetamine withdrawal symptoms. Two authors evaluated and extracted data independently. The data were extracted from intention-to-treat analyses. The Relative Risk (RR) with the 95% confidence interval (95% CI) was used to assess dichotomous outcomes. The Weighted Mean Difference (WMD) with 95% CI was used to assess continuous outcomes. Four randomised controlled trials (involving 125 participants) met the inclusion criteria for the review. Two studies found that amineptine significantly reduced discontinuation rates and improved overall clinical presentation, but did not reduce withdrawal symptoms or craving compared to placebo. The benefits of mirtazapine over placebo for reducing amphetamine withdrawal symptoms were not as clear. One study suggested that mirtazapine may reduce hyperarousal and anxiety symptoms associated with amphetamine withdrawal. A more recent study failed to find any benefit of mirtazapine over placebo on retention or on amphetamine withdrawal symptoms. No medication is effective for treatment of amphetamine

  9. Opiate and opioid withdrawal

    Science.gov (United States)

    ... opiate withdrawal; Oxycontin - opiate withdrawal; Hydrocodone - opiate withdrawal; Detox - opiates; Detoxification - opiates ... facilities set up to help people with detoxification (detox). In a regular hospital, if symptoms are severe. ...

  10. 75 FR 51111 - Notice of Proposed Withdrawal Extension and Opportunity for Public Meeting; Oregon

    Science.gov (United States)

    2010-08-18

    ... protection of the scientific and ecological research values at the Steamboat Mountain Research Natural Area...,400 acres of National Forest System land from mining in order to protect scientific and ecological values at the Steamboat Mountain Research Natural Area. The withdrawal created by PLO No. 6870 will...

  11. People's Front in Defence of Land, San Salvador Atenco: A testimony

    OpenAIRE

    Martha Pérez Pineda

    2011-01-01

    Martha Pérez Pineda gives her statement of the Peoples Front in Defence of the Land (The Peoples Front in Defence of Land (Frente del Pueblo en Defensa de la Tierra, FPDT) was formed in 2002, by residents of San Salvador Atenco, to resist their forced displacement by the federal government of Mexico and Estado de Mexico. The government planned to displace them to make way for the new Mexico City Airport. The people of San Salvador Atenco refused and battled, the most common fights were disput...

  12. Climate Risk and Vulnerability in the Caribbean and Gulf of Mexico Region: Interactions with Spatial Population and Land Cover Change

    Science.gov (United States)

    Chen, R. S.; Levy, M.; Baptista, S.; Adamo, S.

    2010-12-01

    Vulnerability to climate variability and change will depend on dynamic interactions between different aspects of climate, land-use change, and socioeconomic trends. Measurements and projections of these changes are difficult at the local scale but necessary for effective planning. New data sources and methods make it possible to assess land-use and socioeconomic changes that may affect future patterns of climate vulnerability. In this paper we report on new time series data sets that reveal trends in the spatial patterns of climate vulnerability in the Caribbean/Gulf of Mexico Region. Specifically, we examine spatial time series data for human population over the period 1990-2000, time series data on land use and land cover over 2000-2009, and infant mortality rates as a proxy for poverty for 2000-2008. We compare the spatial trends for these measures to the distribution of climate-related natural disaster risk hotspots (cyclones, floods, landslides, and droughts) in terms of frequency, mortality, and economic losses. We use these data to identify areas where climate vulnerability appears to be increasing and where it may be decreasing. Regions where trends and patterns are especially worrisome include coastal areas of Guatemala and Honduras.

  13. Distinguishing Land Change from Natural Variability and Uncertainty in Central Mexico with MODIS EVI, TRMM Precipitation, and MODIS LST Data

    Directory of Open Access Journals (Sweden)

    Zachary Christman

    2016-06-01

    Full Text Available Precipitation and temperature enact variable influences on vegetation, impacting the type and condition of land cover, as well as the assessment of change over broad landscapes. Separating the influence of vegetative variability independent and discrete land cover change remains a major challenge to landscape change assessments. The heterogeneous Lerma-Chapala-Santiago watershed of central Mexico exemplifies both natural and anthropogenic forces enacting variability and change on the landscape. This study employed a time series of Enhanced Vegetation Index (EVI composites from the Moderate Resolution Imaging Spectoradiometer (MODIS for 2001–2007 and per-pixel multiple linear regressions in order to model changes in EVI as a function of precipitation, temperature, and elevation. Over the seven-year period, 59.1% of the variability in EVI was explained by variability in the independent variables, with highest model performance among changing and heterogeneous land cover types, while intact forest cover demonstrated the greatest resistance to changes in temperature and precipitation. Model results were compared to an independent change uncertainty assessment, and selected regional samples of change confusion and natural variability give insight to common problems afflicting land change analyses.

  14. 76 FR 22414 - Amended Proposed Withdrawal, Notice of Public Meetings, Partial Termination of Segregative Effect...

    Science.gov (United States)

    2011-04-21

    ... Withdrawal, Notice of Public Meetings, Partial Termination of Segregative Effect; Arizona, California... the proposed SEZs to include some additional lands. It also terminates the segregative effect as to... proposal is cancelled and the segregative effect established by the June 30, 2009, Notice of Proposed...

  15. [The control of urban growth in Mexico City. Suppositions regarding poor planning].

    Science.gov (United States)

    Aguilar, A G; Olvera, G

    1991-01-01

    It is argued that mechanisms for planning land use and controlling urban expansion in Mexico City have failed to achieve their aims. Although in theory Mexico's urban planning process has recently attempted to go beyond purely physical aspects to include socioeconomic dimensions, it has in fact been inflexible and oriented to exclusively to technical and administrative aspects, to the detriment of social distribution goals. Planning instruments have not included important aspects such as specific mechanisms for altering employment structures or income levels or mechanisms for providing access to land or housing to the most disadvantaged groups. The urban planning process in Mexico City, instead of assuming a socially compensatory role in favor of disadvantaged groups, has maintained the status quo or discriminated in favor of the already advantaged. The spatial and technical orientation or urban planning in Mexico City does not leave room for a well-defined social policy. The population of the Mexico City metropolitan Zone increased from 3 million in 1950 to 18 million in 1985, while its total area increased from 11,750 hectares in 1940 to 125,000 in 1985. Transfer of population from the Federal District to the conurban municipios of the state of Mexico has been very significant since the 1970s. Around 20% of the total area of metropolitan Mexico City has been settled through illegal means, with communal and ejido lands accounting for a large share. Settlements on some 60% of lands in metroplitan Mexico City were illegal or irregular at some time. Low income housing is the cheapest form for the government because the frequently illegal status of settlers prevents them from making any demands for services or equipment for the 1st several years. Construction is undertaken and financed almost entirely by the settlers themselves, freeing the government of responsibility in regard to the constitutionally mandated right of all Mexicans to housing. The Urban Development

  16. Brownfield, TX 1:250,000 Quad USGS Land Use/Land Cover, 2000

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This land cover data set was produced as part of a cooperative project between the U.S. Geological Survey (USGS) and the U.S. Environmental Protection Agency (USEPA)...

  17. Dalhart, TX 1:250,000 Quad USGS Land Use/Land Cover, 2000

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This land cover data set was produced as part of a cooperative project between the U.S. Geological Survey (USGS) and the U.S. Environmental Protection Agency (USEPA)...

  18. Hobbs, NM 1:250,000 Quad USGS Land Use/Land Cover, 2000

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This land cover data set was produced as part of a cooperative project between the U.S. Geological Survey (USGS) and the U.S. Environmental Protection Agency (USEPA)...

  19. Clovis, NM 1:250,000 Quad USGS Land Use/Land Cover, 2000

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This land cover data set was produced as part of a cooperative project between the U.S. Geological Survey (USGS) and the U.S. Environmental Protection Agency (USEPA)...

  20. Tucumcari, NM 1:250,000 Quad USGS Land Use/Land Cover, 2000

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This land cover data set was produced as part of a cooperative project between the U.S. Geological Survey (USGS) and the U.S. Environmental Protection Agency (USEPA)...

  1. Simulated Climate Impacts of Mexico City's Historical Urban Expansion

    Science.gov (United States)

    Benson-Lira, Valeria

    Urbanization, a direct consequence of land use and land cover change, is responsible for significant modification of local to regional scale climates. It is projected that the greatest urban growth of this century will occur in urban areas in the developing world. In addition, there is a significant research gap in emerging nations concerning this topic. Thus, this research focuses on the assessment of climate impacts related to urbanization on the largest metropolitan area in Latin America: Mexico City. Numerical simulations using a state-of-the-science regional climate model are utilized to address a trio of scientifically relevant questions with wide global applicability. The importance of an accurate representation of land use and land cover is first demonstrated through comparison of numerical simulations against observations. Second, the simulated effect of anthropogenic heating is quantified. Lastly, numerical simulations are performed using pre-historic scenarios of land use and land cover to examine and quantify the impact of Mexico City's urban expansion and changes in surface water features on its regional climate.

  2. SOME ASPECTS OF SUSTAINABLE LAND MANAGEMENT AGRICULTURAL LAND USE AREAS WITHIN THE TERRITORIAL COMMUNITIES

    Directory of Open Access Journals (Sweden)

    Kapinos N.

    2016-05-01

    Full Text Available Land Fund in Ukraine is experiencing excessive human impact, which is reflected in its performance exceeding the allowable agricultural development and land structure imbalance. The environmental condition of land resources close to critical. Among the largest land area occupied by agricultural land (71% of which - 76% is arable land. Violation environmentally acceptable ratio of arable land, natural grasslands and forests negatively affected the sustainability of agricultural landscapes. Throughout the widespread land degradation processes, among which the most ambitious is the erosion (about 57.5% of the territory, pollution (20% of the territory, flooding (about 12% of the territory. Sustainable (balanced land is one of the key factors of sustainable nature of territorial entities and may be formed of a priority, taking into account environmental factors. In ecological optimization based on value criteria ekolohostabilizuyuchyh and anthropogenic pressures lands should necessarily provide for withdrawal of intensive land use, which in its modal properties can not ensure sustainability of land use. However, today in Ukraine within the territories of communities no project development to optimize land use on the basis of sustainable development. Accordingly, the purpose of the article was the study of certain aspects of Land Management sustainable development of agricultural land within the territories of local communities. The current structure of the land fund of Ukraine was actually formed in the Soviet period, under the influence of policies of extensive agricultural development. Violation environmentally acceptable ratio of arable land, natural grasslands and forests negatively affected the stability and condition of land, which is confirmed by relevant research. In such circumstances, balancing the land proposed to carry out in two stages - the ecological and economic. In ecological optimization criteria based on land value necessarily

  3. Geospatial analysis of land use and water interaction in the peri-urban area of Cuauhtémoc, Chihuahua. A socio-environmental study in northern Mexico

    Directory of Open Access Journals (Sweden)

    Rolando Enrique Díaz Caravantes

    2013-07-01

    Full Text Available For decades, city growth has been considered only in terms of land availability. In cities of northern Mexico, usually located in arid or semi-arid regions, there is a high dependence on groundwater. For this reason, comprehensive planning urban must consider the peri-urban area not only in terms of soil, but also groundwater. Water transfer for urban use produces severe alterations to the natural environment as aquifer depletion and drastic changes in land use/cover. This paper presents a spatial analysis of land use and water in the peri-urban area of Ciudad Cuauhtémoc. Using geographic modeling and remote sensing we assessed the dynamics of land use/cover. The results indicate that land change processes occur in a context of high competition for water between different users. This process is not usually considered in studies measuring urban spatial expansion, but should be considered to fully understand the effects of urban growth in the territory.

  4. Water withdrawals, use, and trends in Florida, 2010

    Science.gov (United States)

    Marella, Richard L.

    2014-01-01

    -landscape irrigation and domestic self-supplied (5 percent each), and power generation (less than 1 percent). Agricultural self-supplied accounted for 51 percent of fresh surface-water withdrawals, followed by power generation (25 percent), public supply (11 percent), recreational-landscape irrigation (9 percent), and commercial-industrial-mining self-supplied (4 percent). Power generation accounted for nearly all (99.8 percent) saline-water withdrawals. Of the 18.80 million people who resided in Florida during 2010, 41 percent (7.68 million people) resided in the South Florida Water Management District (SFWMD), 25 percent each resided in the Southwest Florida Water Management District (SWFWMD) and the St. Johns River Water Management District (SJRWMD) (4.73 and 4.70 million people, respectively), 7 percent (1.36 million people) resided in the Northwest Florida Water Management District (NWFWMD), and 2 percent (0.33 million people) resided in the Suwannee River Water Management District (SRWMD). The largest percentage of freshwater withdrawals was from the SFWMD (47 percent), followed by the SJRWMD (21 percent), SWFWMD (18 percent), NWFWMD (9 percent), and SRWMD (5 percent). Between 1950 and 2010, the population of Florida increased by 16.03 million (580 percent), and the total water withdrawals (fresh and saline) increased by 12,334 Mgal/d (465 percent). More recently, total freshwater withdrawals decreased by more than 1,792 Mgal/d (22 percent) between 2000 and 2010, while the population increased by 2.82 million (18 percent), and total freshwater withdrawals decreased by more than 474 Mgal/d (7 percent) between 2005 and 2010, while the population increased by 0.88 million (8 percent). The recent trend of decreases in freshwater withdrawals is a result of increased rainfall during this period, the development and use of alternative water sources, water conservation efforts, more conservative regulations and mandates, changes in economic conditions, and losses of irrigated lands

  5. New Mexico Geothermal Data Base

    International Nuclear Information System (INIS)

    Witcher, J.C.; Whittier, J.; Morgan, R.

    1990-01-01

    This paper reports on the New Mexico Geothermal Data Base (NMGDB) which is a comprehensive public-domain data base of low-temperature geothermal resource information for New Mexico that is designed to assist researchers and developers. A broad range of geoscience, engineering, climatic, economic, and land status information are complied in the dBASE III PLUS data base management system for use on an IBM or IBM-compatible personal computer. A user friendly menu format with on-screen prompts allows easy and convenient use

  6. 77 FR 39725 - Land Acquisitions: Pueblo of Santo Domingo

    Science.gov (United States)

    2012-07-05

    ... Counties, New Mexico A parcel of land described as follows: beginning at a monument marking the position..., more or less. Tract B--Ca[ntilde]ada de Santa Fe T. 15 N., R. 7 E., NMPM, Santa Fe County, New Mexico A...

  7. Protected Areas Database for New Mexico

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — The Protected Areas Database of the United States (PAD-US) is a geodatabase, managed by USGS GAP, that illustrates and describes public land ownership, management...

  8. Withdrawal: Expanding a Key Addiction Construct.

    Science.gov (United States)

    Piper, Megan E

    2015-12-01

    Withdrawal is an essential component of classical addiction theory; it is a vital manifestation of dependence and motivates relapse. However, the traditional conceptualization of withdrawal as a cohesive collection of symptoms that emerge during drug deprivation and decline with either the passage of time or reinstatement of drug use, may be inadequate to explain scientific findings or fit with modern theories of addiction. This article expands the current understanding of tobacco withdrawal by examining: (1) withdrawal variability; (2) underlying causes of withdrawal variability, including biological and person factors, environmental influences, and the influence of highly routinized behavioral patterns; (3) new withdrawal symptoms that allow for enhanced characterization of the withdrawal experience; and (4) withdrawal-related cognitive processes. These topics provide guidance regarding the optimal assessment of withdrawal and illustrate the potential impact modern withdrawal conceptualization and assessment could have on identifying treatment targets. © The Author 2015. Published by Oxford University Press on behalf of the Society for Research on Nicotine and Tobacco. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  9. Land Subsidence Caused by Groundwater Exploitation in Quetta Valley, Pakistan

    Directory of Open Access Journals (Sweden)

    Najeebullah Kakar

    2016-12-01

    Full Text Available Land subsidence is affecting several metropolitan cities in developing as well as developed countries around the world such as Nagoya (Japan, Shanghai (China, Venice (Italy and San Joaquin valley (United States. This phenomenon is attributed to natural as well as anthropogenic activities that include extensive groundwater withdrawals. Quetta is the largest city of Balochistan province in Pakistan. This valley is mostly dry and ground water is the major source for domestic and agricultural consumption. The unplanned use of ground water resources has led to the deterioration of water quality and quantity in the Quetta valley. Water shortage in the region was further aggravated by the drought during (1998-2004 that hit the area forcing people to migrate from rural to urban areas. Refugees from the war torn neighboring Afghanistan also contributed to rapid increase in population of Quetta valley that has increased from 0.26 million in 1975 to 3.0 million in 2016. The objective of this study was to measure the land subsidence in Quetta valley and identify the effects of groundwater withdrawals on land subsidence. To achieve this goal, data from five Global Positioning System (GPS stations were acquired and processed. Furthermore the groundwater decline data from 41 observation wells during 2010 to 2015 were calculated and compared with the land deformation. The results of this study revealed that the land of Quetta valley is subsiding from 30mm/y on the flanks to 120 mm/y in the central part. 1.5-5.0 m/y of groundwater level drop was recorded in the area where the rate of subsidence is highest. So the extensive groundwater withdrawals in Quetta valley is considered to be the driving force behind land subsidence.

  10. Resolving the Conflict Between Ecosystem Protection and Land Use in Protected Areas of the Sierra Madre de Chiapas, Mexico

    Science.gov (United States)

    Cortina-Villar, Sergio; Plascencia-Vargas, Héctor; Vaca, Raúl; Schroth, Götz; Zepeda, Yatziri; Soto-Pinto, Lorena; Nahed-Toral, José

    2012-03-01

    Livelihoods of people living in many protected areas (PAs) around the world are in conflict with biodiversity conservation. In Mexico, the decrees of creation of biosphere reserves state that rural communities with the right to use buffer zones must avoid deforestation and their land uses must become sustainable, a task which is not easily accomplished. The objectives of this paper are: (a) to analyze the conflict between people's livelihoods and ecosystem protection in the PAs of the Sierra Madre de Chiapas (SMC), paying special attention to the rates and causes of deforestation and (b) to review policy options to ensure forest and ecosystem conservation in these PAs, including the existing payments for environmental services system and improvements thereof as well as options for sustainable land management. We found that the three largest PAs in the SMC are still largely forested, and deforestation rates have decreased since 2000. Cases of forest conversion are located in specific zones and are related to agrarian and political conflicts as well as growing economic inequality and population numbers. These problems could cause an increase in forest loss in the near future. Payments for environmental services and access to carbon markets are identified as options to ensure forest permanence but still face problems. Challenges for the future are to integrate these incentive mechanisms with sustainable land management and a stronger involvement of land holders in conservation.

  11. Neonatal opioid withdrawal syndrome.

    Science.gov (United States)

    Sutter, Mary Beth; Leeman, Lawrence; Hsi, Andrew

    2014-06-01

    Neonatal opioid withdrawal syndrome is common due to the current opioid addiction epidemic. Infants born to women covertly abusing prescription opioids may not be identified as at risk until withdrawal signs present. Buprenorphine is a newer treatment for maternal opioid addiction and appears to result in a milder withdrawal syndrome than methadone. Initial treatment is with nonpharmacological measures including decreasing stimuli, however pharmacological treatment is commonly required. Opioid monotherapy is preferred, with phenobarbital or clonidine uncommonly needed as adjunctive therapy. Rooming-in and breastfeeding may decease the severity of withdrawal. Limited evidence is available regarding long-term effects of perinatal opioid exposure. Copyright © 2014 Elsevier Inc. All rights reserved.

  12. The Human Footprint in Mexico: Physical Geography and Historical Legacies

    Science.gov (United States)

    Ortega-Rubio, Alfredo; Kolb, Melanie; Bezaury Creel, Juan E.

    2015-01-01

    Using publicly available data on land use and transportation corridors we calculated the human footprint index for the whole of Mexico to identify large-scale spatial patterns in the anthropogenic transformation of the land surface. We developed a map of the human footprint for the whole country and identified the ecological regions that have most transformed by human action. Additionally, we analyzed the extent to which (a) physical geography, expressed spatially in the form of biomes and ecoregions, compared to (b) historical geography, expressed as the spatial distribution of past human settlements, have driven the patterns of human modification of the land. Overall Mexico still has 56% of its land surface with low impact from human activities, but these areas are not evenly distributed. The lowest values are on the arid north and northwest, and the tropical southeast, while the highest values run along the coast of the Gulf of Mexico and from there inland along an east-to-west corridor that follows the Mexican transversal volcanic ranges and the associated upland plateau. The distribution of low- and high footprint areas within ecoregions forms a complex mosaic: the generally well-conserved Mexican deserts have some highly transformed agro-industrial areas, while many well-conserved, low footprint areas still persist in the highly-transformed ecoregions of central Mexico. We conclude that the spatial spread of the human footprint in Mexico is both the result of the limitations imposed by physical geography to human development at the biome level, and, within different biomes, of a complex history of past civilizations and technologies, including the 20th Century demographic explosion but also the spatial pattern of ancient settlements that were occupied by the Spanish Colony. PMID:25803839

  13. The human footprint in Mexico: physical geography and historical legacies.

    Science.gov (United States)

    González-Abraham, Charlotte; Ezcurra, Exequiel; Garcillán, Pedro P; Ortega-Rubio, Alfredo; Kolb, Melanie; Bezaury Creel, Juan E

    2015-01-01

    Using publicly available data on land use and transportation corridors we calculated the human footprint index for the whole of Mexico to identify large-scale spatial patterns in the anthropogenic transformation of the land surface. We developed a map of the human footprint for the whole country and identified the ecological regions that have most transformed by human action. Additionally, we analyzed the extent to which (a) physical geography, expressed spatially in the form of biomes and ecoregions, compared to (b) historical geography, expressed as the spatial distribution of past human settlements, have driven the patterns of human modification of the land. Overall Mexico still has 56% of its land surface with low impact from human activities, but these areas are not evenly distributed. The lowest values are on the arid north and northwest, and the tropical southeast, while the highest values run along the coast of the Gulf of Mexico and from there inland along an east-to-west corridor that follows the Mexican transversal volcanic ranges and the associated upland plateau. The distribution of low- and high footprint areas within ecoregions forms a complex mosaic: the generally well-conserved Mexican deserts have some highly transformed agro-industrial areas, while many well-conserved, low footprint areas still persist in the highly-transformed ecoregions of central Mexico. We conclude that the spatial spread of the human footprint in Mexico is both the result of the limitations imposed by physical geography to human development at the biome level, and, within different biomes, of a complex history of past civilizations and technologies, including the 20th Century demographic explosion but also the spatial pattern of ancient settlements that were occupied by the Spanish Colony.

  14. Control rod withdrawal monitoring device

    International Nuclear Information System (INIS)

    Ebisuya, Mitsuo.

    1984-01-01

    Purpose: To prevent the power ramp even if a plurality of control rods are subjected to withdrawal operation at a time, by reducing the reactivity applied to the reactor. Constitution: The control rod withdrawal monitoring device is adapted to monitor and control the withdrawal of the control rods depending on the reactor power and the monitoring region thereof is divided into a control rod group monitoring region a transition region and a control group monitoring not interfere region. In a case if the distance between a plurality of control rods for which the withdrawal positions are selected is less than a limiting value, the coordinate for the control rods, distance between the control rods and that the control rod distance is shorter are displayed on a display panel, and the withdrawal for the control rods are blocked. Accordingly, even if a plurality of control rods are subjected successively to the withdrawal operation contrary to the control rod withdrawal sequence upon high power operation of the reactor, the power ramp can be prevented. (Kawakami, Y.)

  15. Renewable Energy on Tribal Lands

    Science.gov (United States)

    This page contains presentations from the Brown to Green: Make the Connection to Renewable Energy workshop held in Santa Fe, New Mexico, during December 10-11, 2008 regarding Renewable Energy on Tribal Lands.

  16. Hydrological, ecological, land use, economic, and sociocultural evidence for resilience of traditional irrigation communities in New Mexico, USA

    Science.gov (United States)

    Fernald, A.; Guldan, S.; Boykin, K.; Cibils, A.; Gonzales, M.; Hurd, B. H.; Lopez, S.; Ochoa, C. G.; Ortiz, M.; Rivera, J.; Rodriguez, S.; Steele, C. M.

    2014-02-01

    Southwestern US irrigated landscapes are facing upheaval due to climate change-induced water scarcity and economic change-induced land use conversion. Clues to community longevity are found in the traditionally irrigated valleys of northern New Mexico. Human systems have interacted with hydrologic processes over the last 400 yr in river fed irrigated valleys to create linked systems. In this study, we asked if concurrent data from multiple disciplines show that human adapted hydrologic and socioeconomic systems have created conditions for resilience. We identify and describe several areas of resilience: hydrological, ecological, land use, economic, and sociocultural. We found that there are multiple hydrologic benefits of the water seepage from the traditional irrigation systems; it recharges groundwater that recharges rivers, supports threatened biodiversity by maintaining riparian vegetation, and ameliorates impacts of climate change by prolonging streamflow hydrographs. In terms of land use and economics, place-based adaptability manifests itself in transformations of irrigation infrastructure and specific animal and crop systems; as grazing has diminished over time on public land watersheds, it has increased on irrigated valley pastures while outside income allows irrigators to retain their land. Sociocultural evidence shows that traditional local knowledge about the hydrosocial cycle of acequia operations is a key factor in acequia resilience. When irrigators are confronted with unexpected disturbances or changing climate that affect water supply, they adapt specific practices while maintaining community cohesion. Our ongoing work will quantify the multiple disciplinary components of these systems, translate them into a common language of causal loop diagrams, and model future scenarios to identify thresholds and tipping points of sustainability. Early indications are that these systems are not immune to upheaval, but have astonishing resilience.

  17. Methods for Estimating Water Withdrawals for Mining in the United States, 2005

    Science.gov (United States)

    Lovelace, John K.

    2009-01-01

    Mexico, Texas, and Wyoming, by using data from State agencies that regulate oil and gas extraction. Total water withdrawals for mining in a county were estimated by summing estimated water withdrawals for nonfuels mining, coal mining, and oil and gas extraction. The results of this study were distributed to NWUIP personnel in each State during 2007. NWUIP personnel were required to submit estimated withdrawals for numerous categories of use in their States to a national compilation team for inclusion in a national report describing water use in the United States during 2005. NWUIP personnel had the option of submitting the estimates determined by using the methods described in this report, a modified version of these estimates, or their own set of estimates or reported data. Estimated withdrawals resulting from the methods described in this report may not be included in the national report; therefore the estimates are not presented herein in order to avoid potential inconsistencies with the national report. Water-use coefficients for specific minerals also are not presented to avoid potential disclosure of confidential production data provided by mining operations to the U.S. Geological Survey.

  18. Clifton, AZ 1:250,000 Quad East Half USGS Land Use/Land Cover, 2000

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This land cover data set was produced as part of a cooperative project between the U.S. Geological Survey (USGS) and the U.S. Environmental Protection Agency (USEPA)...

  19. Tularosa, NM 1:250,000 Quad East Half USGS Land Use/Land Cover, 2000

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This land cover data set was produced as part of a cooperative project between the U.S. Geological Survey (USGS) and the U.S. Environmental Protection Agency (USEPA)...

  20. Gallup, NM 1:250,000 Quad West Half USGS Land Use/Land Cover, 2000

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This land cover data set was produced as part of a cooperative project between the U.S. Geological Survey (USGS) and the U.S. Environmental Protection Agency (USEPA)...

  1. Clifton, AZ 1:250,000 Quad West Half USGS Land Use/Land Cover, 2000

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This land cover data set was produced as part of a cooperative project between the U.S. Geological Survey (USGS) and the U.S. Environmental Protection Agency (USEPA)...

  2. Albuquerque, NM 1:250,000 Quad West Half USGS Land Use/Land Cover, 2000

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This land cover data set was produced as part of a cooperative project between the U.S. Geological Survey (USGS) and the U.S. Environmental Protection Agency (USEPA)...

  3. Douglas, AZ 1:250,000 Quad West Half USGS Land Use/Land Cover, 2000

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This land cover data set was produced as part of a cooperative project between the U.S. Geological Survey (USGS) and the U.S. Environmental Protection Agency (USEPA)...

  4. Gallup, NM 1:250,000 Quad East Half USGS Land Use/Land Cover, 2000

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This land cover data set was produced as part of a cooperative project between the U.S. Geological Survey (USGS) and the U.S. Environmental Protection Agency (USEPA)...

  5. Roswell, NM 1:250,000 Quad West Half USGS Land Use/Land Cover, 2000

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This land cover data set was produced as part of a cooperative project between the U.S. Geological Survey (USGS) and the U.S. Environmental Protection Agency (USEPA)...

  6. Socorro, NM 1:250,000 Quad West Half USGS Land Use/Land Cover, 2000

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This land cover data set was produced as part of a cooperative project between the U.S. Geological Survey (USGS) and the U.S. Environmental Protection Agency (USEPA)...

  7. Douglas, AZ 1:250,000 Quad East Half USGS Land Use/Land Cover, 2000

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This land cover data set was produced as part of a cooperative project between the U.S. Geological Survey (USGS) and the U.S. Environmental Protection Agency (USEPA)...

  8. Roswell, NM 1:250,000 Quad East Half USGS Land Use/Land Cover, 2000

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This land cover data set was produced as part of a cooperative project between the U.S. Geological Survey (USGS) and the U.S. Environmental Protection Agency (USEPA)...

  9. Shiprock, NM 1:250,000 Quad West Half USGS Land Use/Land Cover, 2000

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This land cover data set was produced as part of a cooperative project between the U.S. Geological Survey (USGS) and the U.S. Environmental Protection Agency (USEPA)...

  10. Aztec, NM 1:250,000 Quad East Half USGS Land Use/Land Cover, 2000

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This land cover data set was produced as part of a cooperative project between the U.S. Geological Survey (USGS) and the U.S. Environmental Protection Agency (USEPA)...

  11. Aztec, NM 1:250,000 Quad West Half USGS Land Use/Land Cover, 2000

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This land cover data set was produced as part of a cooperative project between the U.S. Geological Survey (USGS) and the U.S. Environmental Protection Agency (USEPA)...

  12. Socorro, NM 1:250,000 Quad East Half USGS Land Use/Land Cover, 2000

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This land cover data set was produced as part of a cooperative project between the U.S. Geological Survey (USGS) and the U.S. Environmental Protection Agency (USEPA)...

  13. Carlsbad, NM 1:250,000 Quad West Half USGS Land Use/Land Cover, 2000

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This land cover data set was produced as part of a cooperative project between the U.S. Geological Survey (USGS) and the U.S. Environmental Protection Agency (USEPA)...

  14. Raton, NM 1:250,000 Quad East Half USGS Land Use/Land Cover, 2000

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This land cover data set was produced as part of a cooperative project between the U.S. Geological Survey (USGS) and the U.S. Environmental Protection Agency (USEPA)...

  15. Shiprock, NM 1:250,000 Quad East Half USGS Land Use/Land Cover, 2000

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This land cover data set was produced as part of a cooperative project between the U.S. Geological Survey (USGS) and the U.S. Environmental Protection Agency (USEPA)...

  16. Albuquerque, NM 1:250,000 Quad East Half USGS Land Use/Land Cover, 2000

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This land cover data set was produced as part of a cooperative project between the U.S. Geological Survey (USGS) and the U.S. Environmental Protection Agency (USEPA)...

  17. Raton, NM 1:250,000 Quad West Half USGS Land Use/Land Cover, 2000

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This land cover data set was produced as part of a cooperative project between the U.S. Geological Survey (USGS) and the U.S. Environmental Protection Agency (USEPA)...

  18. Carlsbad, NM 1:250,000 Quad East Half USGS Land Use/Land Cover, 2000

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This land cover data set was produced as part of a cooperative project between the U.S. Geological Survey (USGS) and the U.S. Environmental Protection Agency (USEPA)...

  19. Tularosa, NM 1:250,000 Quad West Half USGS Land Use/Land Cover, 2000

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This land cover data set was produced as part of a cooperative project between the U.S. Geological Survey (USGS) and the U.S. Environmental Protection Agency (USEPA)...

  20. Las Cruces, NM 1:250,000 Quad West Half USGS Land Use/Land Cover, 2000

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This land cover data set was produced as part of a cooperative project between the U.S. Geological Survey (USGS) and the U.S. Environmental Protection Agency (USEPA)...

  1. Santa Fe, NM 1:250,000 Quad West Half USGS Land Use/Land Cover, 2000

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This land cover data set was produced as part of a cooperative project between the U.S. Geological Survey (USGS) and the U.S. Environmental Protection Agency (USEPA)...

  2. Silver City, NM 1:250,000 Quad East Half USGS Land Use/Land Cover, 2000

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This land cover data set was produced as part of a cooperative project between the U.S. Geological Survey (USGS) and the U.S. Environmental Protection Agency (USEPA)...

  3. El Paso, TX 1:250,000 Quad West Half USGS Land Use/Land Cover, 2000

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This land cover data set was produced as part of a cooperative project between the U.S. Geological Survey (USGS) and the U.S. Environmental Protection Agency (USEPA)...

  4. Silver City, NM 1:250,000 Quad West Half USGS Land Use/Land Cover, 2000

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This land cover data set was produced as part of a cooperative project between the U.S. Geological Survey (USGS) and the U.S. Environmental Protection Agency (USEPA)...

  5. Saint Johns, AZ 1:250,000 Quad East Half USGS Land Use/Land Cover, 2000

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This land cover data set was produced as part of a cooperative project between the U.S. Geological Survey (USGS) and the U.S. Environmental Protection Agency (USEPA)...

  6. Fort Sumner, NM 1:250,000 Quad West Half USGS Land Use/Land Cover, 2000

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This land cover data set was produced as part of a cooperative project between the U.S. Geological Survey (USGS) and the U.S. Environmental Protection Agency (USEPA)...

  7. Las Cruces, NM 1:250,000 Quad East Half USGS Land Use/Land Cover, 2000

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This land cover data set was produced as part of a cooperative project between the U.S. Geological Survey (USGS) and the U.S. Environmental Protection Agency (USEPA)...

  8. El Paso, TX 1:250,000 Quad East Half USGS Land Use/Land Cover, 2000

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This land cover data set was produced as part of a cooperative project between the U.S. Geological Survey (USGS) and the U.S. Environmental Protection Agency (USEPA)...

  9. Santa Fe, NM 1:250,000 Quad East Half USGS Land Use/Land Cover, 2000

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This land cover data set was produced as part of a cooperative project between the U.S. Geological Survey (USGS) and the U.S. Environmental Protection Agency (USEPA)...

  10. Saint Johns, AZ 1:250,000 Quad West Half USGS Land Use/Land Cover, 2000

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This land cover data set was produced as part of a cooperative project between the U.S. Geological Survey (USGS) and the U.S. Environmental Protection Agency (USEPA)...

  11. Fort Sumner, NM 1:250,000 Quad East Half USGS Land Use/Land Cover, 2000

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — This land cover data set was produced as part of a cooperative project between the U.S. Geological Survey (USGS) and the U.S. Environmental Protection Agency (USEPA)...

  12. Spatial and temporal land cover changes in Terminos Lagoon Reserve, Mexico

    Directory of Open Access Journals (Sweden)

    Ernesto Soto-Galera

    2010-06-01

    Full Text Available El ecosistema de Laguna de Términos es el más grande sistema fluvio lagunar estuarino del país y una de las reservas más importantes de flora y fauna costera en México. Desde la década de los setentas, parte de la infraestructura necesaria para la explotación del petróleo en el país se encuentra localizada en esta área. Su importante biodiversidad ha motivado diferentes estudios en el área que incluyen procesos de deforestación y ordenamiento del territorio. Se realizó un análisis de imágenes de satélite para determinar los cambios de uso del suelo y vegetación en el área entre 1974 y 2001. Los resultados indican que la selva tropical y el mangle presentan las mayores pérdidas de cobertura. En contraste, las áreas urbanas y los pastos inducidos han incrementado considerablemente su extensión. En el año 2001 más de la mitad del área ocupada por el ecosistema mostró cambios en sus coberturas originales y una tercera parte estaba deteriorada. La deforestación fue causada principalmente por el incremento de los pastizales y el crecimiento de las áreas urbanas. Sin embargo, estas pérdidas fueron atenuadas por la regeneración natural. Se concluye que la introducción de pasto para la ganadería y el desarrollo urbano fueron las principales causas de los cambios de uso de suelo, sin embargo, la industria petrolera asentada en el ecosistema ha fomentado indirectamente el crecimiento urbano y el auge ganadero.Terminos Lagoon ecosystem is the largest fluvial-lagoon estuarine system in the country and one of the most important reserves of coastal flora and fauna in Mexico. Since the seventies, part of the main infrastructure for country’s oil extraction is located in this area. Its high biodiversity has motivated different type of studies including deforestation processes and land use planning. In this work we used satellite image analysis to determine land cover changes in the area from 1974 to 2001. Our results indicate

  13. Land subsidence, Ground Fissures and Buried Faults: InSAR Monitoring of Ciudad Guzmán (Jalisco, Mexico

    Directory of Open Access Journals (Sweden)

    Carlo Alberto Brunori

    2015-07-01

    Full Text Available We study land subsidence processes and the associated ground fissuring, affecting an active graben filled by thick unconsolidated deposits by means of InSAR techniques and fieldwork. On 21 September 2012, Ciudad Guzmán (Jalisco, Mexico was struck by ground fissures of about 1.5 km of length, causing the deformation of the roads and the propagation of fissures in adjacent buildings. The field survey showed that fissures alignment is coincident with the escarpments produced on 19 September 1985, when a strong earthquake with magnitude 8.1 struck central Mexico. In order to detect and map the spatio-temporal features of the processes that led to the 2012 ground fissures, we applied InSAR multi-temporal techniques to process ENVISAT-ASAR and RADARSAT-2 satellite SAR images acquired between 2003 and 2012. We detect up to 20 mm/year of subsidence of the northwestern part of Ciudad Guzmán. These incremental movements are consistent with the ground fissures observed in 2012. Based on interferometric results, field data and 2D numerical model, we suggest that ground deformations and fissuring are due to the presence of areal subsidence correlated with variable sediment thickness and differential compaction, partly driven by the exploitation of the aquifers and controlled by the distribution and position of buried faults.

  14. Is this ?complicated? opioid withdrawal?

    OpenAIRE

    Parkar, S.R.; Seethalakshmi, R; Adarkar, S; Kharawala, S

    2006-01-01

    Seven patients with opioid dependence admitted in the de-addiction centre for detoxification developed convulsions and delirium during the withdrawal phase. After ruling out all other possible causes of these complications, opioid withdrawal seemed to emerge as the most likely explanation. The unpredictability of the course of opioid dependence and withdrawal needs to be considered when treating patients with opioid dependence.

  15. Trends in marine debris in the U.S. Caribbean and the Gulf of Mexico, 1996-2003

    Science.gov (United States)

    Ribic, Christine; Seba B. Sheavly,; Rugg, David J.

    2011-01-01

    Marine debris is a widespread and globally recognized problem. Sound information is necessary to understand the extent of the problem and to inform resource managers and policy makers about potential mitigation strategies. Although there are many short-term studies on marine debris, a longer-term perspective and the ability to compare among regions has heretofore been missing in the U.S. Caribbean and the Gulf of Mexico. We used data from a national beach monitoring program to evaluate and compare amounts, composition, and trends of indicator marine debris in the U.S. Caribbean (Puerto Rico and the U.S. Virgin Islands) and the Gulf of Mexico from 1996 to 2003. Indicator items provided a standardized set that all surveys collected; each was assigned a probable source: ocean-based, land-based, or general-source. Probable ocean-based debris was related to activities such as recreational boating/fishing, commercial fishing and activities on oil/gas platforms. Probable land-based debris was related to land-based recreation and sewer systems. General-source debris represented plastic items that can come from either ocean- or land-based sources; these items were plastic bags, strapping bands, and plastic bottles (excluding motor oil containers). Debris loads were similar between the U.S. Caribbean and the western Gulf of Mexico; however, debris composition on U.S. Caribbean beaches was dominated by land-based indicators while the western Gulf of Mexico was dominated by ocean-based indicators. Beaches along the eastern Gulf of Mexico had the lowest counts of debris; composition was dominated by land-based indicators, similar to that found for the U.S. Caribbean. Debris loads on beaches in the Gulf of Mexico are likely affected by Gulf circulation patterns, reducing loads in the eastern Gulf and increasing loads in the western Gulf. Over the seven years of monitoring, we found a large linear decrease in total indicator debris, as well as all source categories, for the U

  16. Can conservation funding be left to carbon finance? Evidence from participatory future land use scenarios in Peru, Indonesia, Tanzania, and Mexico

    Science.gov (United States)

    Ravikumar, Ashwin; Larjavaara, Markku; Larson, Anne; Kanninen, Markku

    2017-01-01

    Revenues derived from carbon have been seen as an important tool for supporting forest conservation over the past decade. At the same time, there is high uncertainty about how much revenue can reasonably be expected from land use emissions reductions initiatives. Despite this uncertainty, REDD+ projects and conservation initiatives that aim to take advantage of available or, more commonly, future funding from carbon markets have proliferated. This study used participatory multi-stakeholder workshops to develop divergent future scenarios of land use in eight landscapes in four countries around the world: Peru, Indonesia, Tanzania, and Mexico. The results of these future scenario building exercises were analyzed using a new tool, CarboScen, for calculating the landscape carbon storage implications of different future land use scenarios. The findings suggest that potential revenues from carbon storage or emissions reductions are significant in some landscapes (most notably the peat forests of Indonesia), and much less significant in others (such as the low-carbon forests of Zanzibar and the interior of Tanzania). The findings call into question the practicality of many conservation programs that hinge on expectations of future revenue from carbon finance. The future scenarios-based approach is useful to policy-makers and conservation program developers in distinguishing between landscapes where carbon finance can substantially support conservation, and landscapes where other strategies for conservation and land use should be prioritized.

  17. Land Subsidence International Symposium held in Venice

    Science.gov (United States)

    The Third International Symposium on Land Subsidence was held March 18-25, 1984, in Venice, Italy. Sponsors were the Ground-Water Commission of the International Association of Hydrological Sciences (IAHS), the United Nations Educational, Scientific, and Cultural Organization (UNESCO), the Italian National Research Council (CNR), the Italian Regions of Veneto and Emilia-Romagna, the Italian Municipalities of Venice, Ravenna, and Modena, the Venice Province, and the European Research Office. Cosponsors included the International Association of Hydrogeologists (IAH), the International Society for Soil Mechanics and Foundation Engineering (ISSMFE), and the Association of Geoscientists for International Development (AGID).Organized within the framework of UNESCO's International Hydrological Program, the symposium brought together over 200 international interdisciplinary specialists in the problems of land subsidence due to fluid and mineral withdrawal. Because man's continuing heavy development of groundwater, gas, oil, and minerals is changing the natural regime and thus causing more and more subsiding areas in the world, there had been sufficient new land subsidence occurrence, problems, research, and remedial measures since the 1976 Second International Symposium held in Anaheim, California, to develop a most interesting program of nearly 100 papers from about 30 countries. The program consisted of papers covering case histories of fluid and mineral withdrawal, engineering theory and analysis, karst “sink-hole”-type subsidence, subsidence due to dewatering of organic deposits or due to application of water (hydrocompaction), instrumentation, legal, socioeconomic, and environmental effects of land subsidence, and remedial works.

  18. Tourism and territorial structure in Ciudad Juarez, Mexico

    OpenAIRE

    Oswaldo Gallegos; Alvarado López López

    2012-01-01

    This paper deals with the issue of the territorial structure of tourism in Ciudad Juarez, Mexico. To do this, the study is divided into two major parts: first, theoretical aspects, given support to our analysis, and a brief history of tourism in the Northern borderlands of Mexico are presented. Then, four basic components of the territorial structure of tourism in Ciudad Juarez are examined: natural and cultural attractions, urban land-use, communications network centred around the city and v...

  19. Land-use and Land-cover Change from 1974 to 2008 around Mobile Bay

    Science.gov (United States)

    Ellis, Jean; Spruce, Joseph; Smoot, James; Hilbert, Kent; Swann, Roberta

    2008-01-01

    This project is a Gulf of Mexico Application Pilot in which NASA Stennis Space Center (SSC) is working within a regional collaboration network of the Gulf of Mexico Alliance. NASA researchers, with support from the NASA SSC Applied Science Program Steering Committee, employed multi-temporal Landsat data to assess land-use and land-cover (LULC) changes in the coastal counties of Mobile and Baldwin, AL, between 1974 and 2008. A multi-decadal time-series, coastal LULC product unique to NASA SSC was produced. The geographic extent and nature of change was quantified for the open water, barren, upland herbaceous, non-woody wetland, upland forest, woody wetland, and urban landscapes. The National Oceanic and Atmospheric Administration (NOAA) National Coastal Development Data Center (NCDDC) will assist with the transition of the final product to the operational end user, which primarily is the Mobile Bay National Estuary Program (MBNEP). We found substantial LULC change over the 34-year study period, much more than is evident when the change occurring in the last years. Between 1974 and 2008, the upland forest landscape lost almost 6% of the total acreage, while urban land cover increased by slightly more than 3%. With exception to open water, upland forest is the dominant landscape, accounting for about 25-30% of the total area.

  20. 19 CFR 144.38 - Withdrawal for consumption.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 2 2010-04-01 2010-04-01 false Withdrawal for consumption. 144.38 Section 144.38... Withdrawal for consumption. (a) Form. Withdrawals for consumption of merchandise in bonded warehouses shall... considered a withdrawal for consumption pursuant to § 181.53 of this chapter. (c) Information to be shown on...

  1. Land subsidence and earth fissures in south-central and southern Arizona, USA

    Science.gov (United States)

    Conway, Brian D.

    2016-05-01

    Land subsidence due to groundwater overdraft has been an ongoing problem in south-central and southern Arizona (USA) since the 1940s. The first earth fissure attributed to excessive groundwater withdrawal was discovered in the early 1950s near Picacho. In some areas of the state, groundwater-level declines of more than 150 m have resulted in extensive land subsidence and earth fissuring. Land subsidence in excess of 5.7 m has been documented in both western metropolitan Phoenix and Eloy. The Arizona Department of Water Resources (ADWR) has been monitoring land subsidence since 2002 using interferometric synthetic aperture radar (InSAR) and since 1998 using a global navigation satellite system (GNSS). The ADWR InSAR program has identified more than 25 individual land subsidence features that cover an area of more than 7,300 km2. Using InSAR data in conjunction with groundwater-level datasets, ADWR is able to monitor land subsidence areas as well as identify areas that may require additional monitoring. One area of particular concern is the Willcox groundwater basin in southeastern Arizona, which is the focus of this paper. The area is experiencing rapid groundwater declines, as much as 32.1 m during 2005-2014 (the largest land subsidence rate in Arizona State—up to 12 cm/year), and a large number of earth fissures. The declining groundwater levels in Arizona are a challenge for both future groundwater availability and mitigating land subsidence associated with these declines. ADWR's InSAR program will continue to be a critical tool for monitoring land subsidence due to excessive groundwater withdrawal.

  2. Exploring dust emission responses to land cover change using an ecological land classification

    Science.gov (United States)

    Galloza, Magda S.; Webb, Nicholas P.; Bleiweiss, Max P.; Winters, Craig; Herrick, Jeffrey E.; Ayers, Eldon

    2018-06-01

    Despite efforts to quantify the impacts of land cover change on wind erosion, assessment uncertainty remains large. We address this uncertainty by evaluating the application of ecological site concepts and state-and-transition models (STMs) for detecting and quantitatively describing the impacts of land cover change on wind erosion. We apply a dust emission model over a rangeland study area in the northern Chihuahuan Desert, New Mexico, USA, and evaluate spatiotemporal patterns of modelled horizontal sediment mass flux and dust emission in the context of ecological sites and their vegetation states; representing a diversity of land cover types. Our results demonstrate how the impacts of land cover change on dust emission can be quantified, compared across land cover classes, and interpreted in the context of an ecological model that encapsulates land management intensity and change. Results also reveal the importance of established weaknesses in the dust model soil characterisation and drag partition scheme, which appeared generally insensitive to the impacts of land cover change. New models that address these weaknesses, coupled with ecological site concepts and field measurements across land cover types, could significantly reduce assessment uncertainties and provide opportunities for identifying land management options.

  3. Anticonvulsants for alcohol withdrawal.

    Science.gov (United States)

    Minozzi, Silvia; Amato, Laura; Vecchi, Simona; Davoli, Marina

    2010-03-17

    Alcohol abuse and dependence represents a most serious health problem worldwide with major social, interpersonal and legal interpolations. Besides benzodiazepines, anticonvulsants are often used for the treatment of alcohol withdrawal symptoms. Anticonvulsants drugs are indicated for the treatment of alcohol withdrawal syndrome, alone or in combination with benzodiazepine treatments. In spite of the wide use, the exact role of the anticonvulsants for the treatment of alcohol withdrawal has not yet bee adequately assessed. To evaluate the effectiveness and safety of anticonvulsants in the treatment of alcohol withdrawal. We searched Cochrane Drugs and Alcohol Group' Register of Trials (December 2009), PubMed, EMBASE, CINAHL (1966 to December 2009), EconLIT (1969 to December 2009). Parallel searches on web sites of health technology assessment and related agencies, and their databases. Randomized controlled trials (RCTs) examining the effectiveness, safety and overall risk-benefit of anticonvulsants in comparison with a placebo or other pharmacological treatment. All patients were included regardless of age, gender, nationality, and outpatient or inpatient therapy. Two authors independently screened and extracted data from studies. Fifty-six studies, with a total of 4076 participants, met the inclusion criteria. Comparing anticonvulsants with placebo, no statistically significant differences for the six outcomes considered.Comparing anticonvulsant versus other drug, 19 outcomes considered, results favour anticonvulsants only in the comparison carbamazepine versus benzodiazepine (oxazepam and lorazepam) for alcohol withdrawal symptoms (CIWA-Ar score): 3 studies, 262 participants, MD -1.04 (-1.89 to -0.20), none of the other comparisons reached statistical significance.Comparing different anticonvulsants no statistically significant differences in the two outcomes considered.Comparing anticonvulsants plus other drugs versus other drugs (3 outcomes considered), results

  4. Tourism and territorial structure in Ciudad Juarez, Mexico

    Directory of Open Access Journals (Sweden)

    Oswaldo Gallegos

    2012-02-01

    Full Text Available This paper deals with the issue of the territorial structure of tourism in Ciudad Juarez, Mexico. To do this, the study is divided into two major parts: first, theoretical aspects, given support to our analysis, and a brief history of tourism in the Northern borderlands of Mexico are presented. Then, four basic components of the territorial structure of tourism in Ciudad Juarez are examined: natural and cultural attractions, urban land-use, communications network centred around the city and visitors and tourist flows.

  5. Development of an expert analysis tool based on an interactive subsidence hazard map for urban land use in the city of Celaya, Mexico

    Science.gov (United States)

    Alloy, A.; Gonzalez Dominguez, F.; Nila Fonseca, A. L.; Ruangsirikulchai, A.; Gentle, J. N., Jr.; Cabral, E.; Pierce, S. A.

    2016-12-01

    Land Subsidence as a result of groundwater extraction in central Mexico's larger urban centers initiated in the 80's as a result of population and economic growth. The city of Celaya has undergone subsidence for a few decades and a consequence is the development of an active normal fault system that affects its urban infrastructure and residential areas. To facilitate its analysis and a land use decision-making process we created an online interactive map enabling users to easily obtain information associated with land subsidence. Geological and socioeconomic data of the city was collected, including fault location, population data, and other important infrastructure and structural data has been obtained from fieldwork as part of a study abroad interchange undergraduate course. The subsidence and associated faulting hazard map was created using an InSAR derived subsidence velocity map and population data from INEGI to identify hazard zones using a subsidence gradient spatial analysis approach based on a subsidence gradient and population risk matrix. This interactive map provides a simple perspective of different vulnerable urban elements. As an accessible visualization tool, it will enhance communication between scientific and socio-economic disciplines. Our project also lays the groundwork for a future expert analysis system with an open source and easily accessible Python coded, SQLite database driven website which archives fault and subsidence data along with visual damage documentation to civil structures. This database takes field notes and provides an entry form for uniform datasets, which are used to generate a JSON. Such a database is useful because it allows geoscientists to have a centralized repository and access to their observations over time. Because of the widespread presence of the subsidence phenomena throughout cities in central Mexico, the spatial analysis has been automated using the open source software R. Raster, rgeos, shapefiles, and rgdal

  6. Application of InSAR and Gravimetry for Land Subsidence Hazard Zoning in Aguascalientes, Mexico

    Directory of Open Access Journals (Sweden)

    Jesús Pacheco-Martínez

    2015-12-01

    Full Text Available In this work we present an application of InSAR and gravimetric surveys for risk management related to land subsidence and surface ground faulting generation. A subsidence velocity map derived from the 2007–2011 ALOS SAR imagery and a sediment thicknesses map obtained from the inversion of gravimetric data were integrated with a surface fault map to produce a subsidence hazard zoning in the city of Aguascalientes, Mexico. The resulting zoning is presented together with specific recommendations about geotechnical studies needed for further evaluation of surface faulting in these hazard zones. The derived zoning map consists in four zones including null hazard (stable terrain without subsidence, low hazard (areas prone to subsidence, medium hazard (zones with subsidence and high hazard (zones with surface faulting. InSAR results displayed subsidence LOS velocities up to 10 cm/year and two subsidence areas unknown before this study. Gravimetric results revealed that the thicker sediment sequence is located toward north of Aguascalientes City reaching up to 600 m in thickness, which correspond to a high subsidence LOS velocity zone (up to 6 cm/year.

  7. Perinatal risk factors and social withdrawal behaviour.

    Science.gov (United States)

    Guedeney, Antoine; Marchand-Martin, Laetitia; Cote, Sylvana J; Larroque, Béatrice

    2012-04-01

    The objectives of the study were (1) to assess prevalence of social withdrawal behaviour in infants aged 12 months included in the French Perinatal Risk Factor Study Eden; (2) To study the correlation between relational withdrawal and several perinatal and parental factors assessed in the EDEN study. A longitudinal study using the ADBB scale was conducted within the Eden Cohort in the year 2008. 1,586 infants were included in the study. Fourteen percent of the children who had an ADBB assessment had a score at 5 and over on the ADBB, a scale designed to assess social withdrawal behaviour at age 0-24 months. Social withdrawal at 12 months was associated with low birth weight, low gestational age and with intra uterine growth retardation. Social withdrawal was independently associated with several maternal and paternal risk factors. The level of social withdrawal behaviour increased with a score of maternal difficulties. This study on a large longitudinally followed volunteer sample demonstrate a clear association of social withdrawal behaviour at age one with low birth weight and preterm birth, possibly mediated by parental vulnerabilities. Social withdrawal behaviour seems to be an important alarm signal to detect early on particularly in premature and small for date babies. © Springer-Verlag 2012

  8. Clinical management of alcohol withdrawal: A systematic review

    Directory of Open Access Journals (Sweden)

    Shivanand Kattimani

    2013-01-01

    Full Text Available Alcohol withdrawal is commonly encountered in general hospital settings. It forms a major part of referrals received by a consultation-liaison psychiatrist. This article aims to review the evidence base for appropriate clinical management of the alcohol withdrawal syndrome. We searched Pubmed for articles published in English on pharmacological management of alcohol withdrawal in humans with no limit on the date of publication. Articles not relevant to clinical management were excluded based on the titles and abstract available. Full-text articles were obtained from this list and the cross-references. There were four meta-analyses, 9 systematic reviews, 26 review articles and other type of publications like textbooks. Alcohol withdrawal syndrome is a clinical diagnosis. It may vary in severity. Complicated alcohol withdrawal presents with hallucinations, seizures or delirium tremens. Benzodiazepines have the best evidence base in the treatment of alcohol withdrawal, followed by anticonvulsants. Clinical institutes withdrawal assessment-alcohol revised is useful with pitfalls in patients with medical comorbidities. Evidence favors an approach of symptom-monitored loading for severe withdrawals where an initial dose is guided by risk factors for complicated withdrawals and further dosing may be guided by withdrawal severity. Supportive care and use of vitamins is also discussed.

  9. Solving problems of modern land relations on the way of formation of competitive agrarian production in Ukraine

    Directory of Open Access Journals (Sweden)

    Skoruk Olena P.

    2014-01-01

    Full Text Available The goal of the article is identification of modern problems of conduct of the land reform and ways of their solution in the context of economic consequences for development of the competitive agrarian production in Ukraine. It identifies that the main task of completion of the land reform is creation of the land market, which would ensure transition of the right of ownership on land lots to an efficient land owner. The basis of this development are farms that combine the owner and master of land in one entity. The article shows that adoption of the Draft Law “On Agricultural Land Turnover” would facilitate development of this form of management. The article identifies main problems of the moratorium on agricultural land sales, namely: land black market activity, withdrawal from market turnover of land of about USD 40 thousand million cost and, as a result, impossibility for agrarians to apply mortgage. The article identifies gaps in the legislation with respect to state control over unclaimed shares and escheats, due to which the state budget does not receive significant amounts of money. It offers ways of solution of these problems through empowering the founded Goszembank, which should become a partner and support for development of small and medium farms after withdrawal of the moratorium on agricultural land sales, with relevant authorities.

  10. 76 FR 6155 - Notice of Realty Action: Competitive Sale of Public Lands in Sandoval County, NM

    Science.gov (United States)

    2011-02-03

    ...., New Mexico 87107, or by calling (505) 761-8700. To establish the fair market value for the subject... to offer, by competitive sale, a parcel of Federally owned land near Golden, New Mexico, containing... conducted in Albuquerque, New Mexico, as a competitive sealed bid auction in which interested bidders must...

  11. Prediction of withdrawal symptoms during opioid detoxification

    NARCIS (Netherlands)

    Dijkstra, Boukje A G; Krabbe, Paul F M; De Jong, Cor A J; van der Staak, Cees P F

    2008-01-01

    OBJECTIVE: The severity of self-reported withdrawal symptoms varies during detoxification of opioid-dependent patients. The aim of this study is to identify subgroups of withdrawal symptoms within the detoxification trajectory and to predict the severity of withdrawal symptoms on the basis of

  12. Prediction of withdrawal symptoms during opioid detoxification

    NARCIS (Netherlands)

    Dijkstra, B.A.G.; Krabbe, P.F.M.; Jong, C.A.J. de; Staak, C.P.F. van der

    2008-01-01

    Objective: The severity of self-reported withdrawal symptoms varies during detoxification of opioid-dependent patients. The aim of this study is to identify subgroups of withdrawal symptoms within the detoxification trajectory and to predict the severity of withdrawal symptoms on the basis of

  13. Water withdrawals, wastewater discharge, and water consumption in the Apalachicola-Chattahoochee-Flint River Basin, 2005, and water-use trends, 1970-2005

    Science.gov (United States)

    Marella, Richard L.; Fanning, Julia L.

    2011-01-01

    The Apalachicola-Chattahoochee-Flint (ACF) River Basin covers about 20,500 square miles that drains parts of Alabama, Florida, and Georgia. The basin extends from its headwaters northern Georgia to the Gulf of Mexico. Population in the basin was estimated to be 3.7 million in 2005, an increase of about 41 percent from the 1990 population of 2.6 million. In 2005, slightly more than 721,000 acres of crops were irrigated within the basin. In 2005, the total amount of water withdrawn in the ACF River Basin was about 1,990 million gallons per day (Mgal/d). Of this, surface water accounted for 1,591 Mgal/d (80 percent) and groundwater accounted for 399 Mgal/d (20 percent). Surface water was the primary water source of withdrawals in the northern and central parts of the basin, and groundwater was the primary source in the southern part. The largest surface-water withdrawals was from Cobb County, Georgia (410 Mgal/d, mostly from the Chattahoochee River and Lake Alatoona), and the largest groundwater withdrawals was from Dougherty County, Georgia (38 Mgal/d, mostly from the Upper Floridan aquifer system).

  14. Control rod excess withdrawal prevention device

    International Nuclear Information System (INIS)

    Takayama, Yoshihito.

    1992-01-01

    Excess withdrawal of a control rod of a BWR type reactor is prevented. That is, the device comprises (1) a speed detector for detecting the driving speed of a control rod, (2) a judging circuit for outputting an abnormal signal if the driving speed is greater than a predetermined level and (3) a direction control valve compulsory closing circuit for controlling the driving direction of inserting and withdrawing a control rod based on an abnormal signal. With such a constitution, when the with drawing speed of a control rod is greater than a predetermined level, it is detected by the speed detector and the judging circuit. Then, all of the direction control valve are closed by way of the direction control valve compulsory closing circuit. As a result, the operation of the control rod is stopped compulsorily and the withdrawing speed of the control rod can be lowered to a speed corresponding to that upon gravitational withdrawal. Accordingly, excess withdrawal can be prevented. (I.S)

  15. 19 CFR 144.37 - Withdrawal for exportation.

    Science.gov (United States)

    2010-04-01

    ...) Class 9 warehouse withdrawals for exportation—(1) Applicability of sales ticket procedure. Merchandise... be eligible for withdrawal under the sales ticket procedure specified in this paragraph. (2) Sales ticket content and handling. Sales ticket withdrawals must be made only under a blanket permit to...

  16. Environmental degradation and migration: the U.S.-Mexico case study.

    Science.gov (United States)

    1998-01-01

    This article provides a detailed account of the conclusions and policy recommendations of a study of environmental degradation and migration between the US and Mexico. Key recommendations and findings were included in the official US Congressional Commission on Immigration Reform report (September 1997). The Congressional report urges Congress to consider environment and development root causes of migration in establishing foreign policies with Mexico and other countries. It appears that the root cause of Mexican migration is rural land degradation or desertification. The study suggests feasible solutions, and not additional border security and employment-related sanctions. The US has the technology and expertise to facilitate programs that address environmental and development issues in targeted and integrated ways. The recommendations serve as a framework for policy reform and debate on rural development and agricultural productivity. Mexican states should be targeted that are new migration-sending states with extensive poverty and soil erosion problems and well-established migration states. Environment, population, and migration are all housed in the Global Affairs Office in the US Department of State, but there is little program integration. The USAID bureaucracy separates agricultural and environmental programs. Solutions include, for example, reducing the costs of remittances from the US to Mexico, conducting research on integrated solutions, and contributing to improved land and water management practices, forest management and land tenure, and the competitiveness of smallholders.

  17. 5 CFR 362.207 - Withdrawal and readmission.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Withdrawal and readmission. 362.207... PRESIDENTIAL MANAGEMENT FELLOWS PROGRAM Program Administration § 362.207 Withdrawal and readmission. (a...) An agency must notify OPM when a Fellow or Senior Fellow withdraws from the Program. (b) Readmission...

  18. Tobacco withdrawal among opioid-dependent smokers.

    Science.gov (United States)

    Streck, Joanna M; Heil, Sarah H; Higgins, Stephen T; Bunn, Janice Y; Sigmon, Stacey C

    2018-04-01

    Prevalence of cigarette smoking among opioid-dependent individuals is 6-fold that of the general U.S. adult population and their quit rates are notoriously poor. One possible reason for the modest cessation outcomes in opioid-dependent smokers may be that they experience more severe tobacco withdrawal upon quitting. In this secondary analysis, we evaluated tobacco withdrawal in opioid-dependent (OD) smokers versus smokers without co-occurring substance use disorders (SUDs). Participants were 47 methadone- or buprenorphine-maintained smokers and 25 non-SUD smokers who completed 1 of several 2-week studies involving daily visits for biochemical monitoring, delivery of financial incentives contingent on smoking abstinence, and assessment of withdrawal via the Minnesota Nicotine Withdrawal Scale (MNWS). Prior to quitting smoking, OD smokers presented with higher baseline withdrawal scores than non-SUD smokers (1.7 ± 0.2 vs. 0.7 ± 0.2, respectively; F [1, 63] = 7.31, p non-SUD smokers, suggesting that elevated withdrawal severity following quitting may not be a major factor contributing to the poor cessation outcomes consistently observed among OD smokers. Further scientific efforts are needed to improve our understanding of the high smoking rates and modest cessation outcomes in this challenging population. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

  19. On the relationship between Indian summer monsoon withdrawal and Indo-Pacific SST anomalies before and after 1976/1977 climate shift

    Energy Technology Data Exchange (ETDEWEB)

    Sabeerali, C.T.; Rao, Suryachandra A. [Indian Institute of Tropical Meteorology, Pune (India); Ajayamohan, R.S. [University of Victoria, Canadian Centre for Climate Modelling and Analysis, Victoria, BC (Canada); Murtugudde, Raghu [University of Maryland, Earth System Science Interdisciplinary Center, College Park, MD (United States)

    2012-08-15

    A clear shift in the withdrawal dates of the Indian Summer Monsoon is observed in the long term time series of rainfall data. Prior (posterior) to the 1976/1977 climate shift most of the withdrawal dates are associated with a late (an early) withdrawal. As a result, the length of the rainy season (LRS) over the Indian land mass has also undergone similar changes (i.e., longer (shorter) LRS prior (posterior) to the climate shift). In this study, probable reasons for this significant shift in withdrawal dates and the LRS are investigated using reanalysis/observed datasets and also with the help of an atmospheric general circulation model. Reanalysis/observational datasets indicate that prior to the climate shift the sea surface temperature (SST) anomalies in the eastern equatorial Pacific Ocean and the Arabian Sea exerted a strong influence on both the withdrawal and the LRS. After the climate shift, the influence of the eastern equatorial Pacific Ocean SST has decreased and surprisingly, the influence of the Arabian Sea SST is almost non-existent. On the other hand, the influence of the southeastern equatorial Indian Ocean has increased significantly. It is observed that the upper tropospheric temperature gradient over the dominant monsoon region has decreased and the relative influence of the Indian Ocean SST variability on the withdrawal of the Indian Summer Monsoon has increased in the post climate shift period. Sensitivity experiments with the contrasting SST patterns on withdrawal dates and the LRS in the pre- and post- climate shift scenarios, confirm the observational evidences presented above. (orig.)

  20. Regional, holocene records of the human dimension of global change: sea-level and land-use change in prehistoric Mexico

    Science.gov (United States)

    Sluyter, Andrew

    1997-02-01

    Regional, Holocene records hold particular relevance for understanding the reciprocal nature of global environmental change and one of its major human dimensions: "sustainable agriculture", i.e., food production strategies which entail fewer causes of and are less susceptible to environmental change. In an epoch of accelerating anthropogenic transformation, those records reveal the protracted regional causes and consequences of change (often agricultural) in the global system as well as informing models of prehistoric, intensive agriculture which, because of long tenures and high productivities, suggest strategies for sustainable agricultural in the present. This study employs physiographic analysis and the palynological, geochemical record from cores of basin fill to understand the reciprocal relation between environmental and land-use change in the Gulf of Mexico tropical lowland, focusing on a coastal basin sensitive to sea-level change and containing vestiges of prehistoric settlement and wetland agriculture. Fossil pollen reveals that the debut of maize cultivation in the Laguna Catarina watershed dates to ca. 4100 BC, predating the earliest evidence for that cultivar anywhere else in the lowlands of Middle America. Such an early date for a cultivar so central to Neotropical agroecology and environmental change, suggests the urgency of further research in the study region. Moreover, the longest period of continuous agriculture in the basin lasted nearly three millennia (ca. 2400 BC-AD 550) despite eustatic sea-level rise. Geochemical fluxes reveal the reciprocity between land-use and environmental change: slope destabilization, basin aggradation, and eutrophication. The consequent theoretical implications pertain to both applied and basic research. Redeploying ancient agroecologies in dynamic environments necessitates reconstructing the changing operational contexts of putative high productivity and sustainability. Adjusting land use in the face of global

  1. Water withdrawals in Florida, 2012

    Science.gov (United States)

    Marella, Richard L.

    2015-09-01

    In 2012, the total amount of water withdrawn in Florida was estimated to be 14,237 million gallons per day (Mgal/d). Saline water accounted for 7,855 Mgal/d (55 percent), and freshwater accounted for 6,383 Mgal/d (45 percent). Groundwater accounted for 4,167 Mgal/d (65 percent) of freshwater withdrawals, and surface water accounted for the remaining 2,216 Mgal/d (35 percent). Surface water accounted for nearly all (99.9 percent) saline-water withdrawals. Freshwater withdrawals were greatest in Palm Beach County (682 Mgal/d), and saline-water withdrawals were greatest in Pasco County (1,822 Mgal/d). Fresh groundwater provided drinking water (through either public supply or private domestic wells) for 17.699 million residents (93 percent of Florida’s population), and fresh surface water provided drinking water for 1.375 million residents (7 percent). The statewide public-supply gross per capita water use for 2012 was estimated at 136 gallons per day.

  2. The benzodiazepine withdrawal syndrome and its management.

    OpenAIRE

    Onyett, S R

    1989-01-01

    The literature on benzodiazepine dependence and withdrawal is reviewed with an emphasis on social and psychological considerations. The problems of when to prescribe, identifying withdrawal symptoms, effective communication with the patient, the structure of withdrawal programmes, and the use of drugs, psychological approaches and other services are discussed.

  3. 47 CFR 1.8 - Withdrawal of papers.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Withdrawal of papers. 1.8 Section 1.8 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL PRACTICE AND PROCEDURE General Rules of Practice and Procedure General § 1.8 Withdrawal of papers. The granting of a request to dismiss or withdraw an...

  4. 29 CFR 102.104 - Withdrawal of petition.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 2 2010-07-01 2010-07-01 false Withdrawal of petition. 102.104 Section 102.104 Labor... Orders and Advisory Opinions Regarding Board Jurisdiction § 102.104 Withdrawal of petition. The petitioner may withdraw his petition at any time prior to issuance of the Board's advisory opinion. ...

  5. North American Land Change Monitoring System (NALCMS) Collection

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — The North American Land Change Monitoring System (NALCMS) is a trilateral effort between Canada, the United States, and Mexico, and is produced by the Canada Centre...

  6. Quantifying the Clinical Significance of Cannabis Withdrawal

    Science.gov (United States)

    Allsop, David J.; Copeland, Jan; Norberg, Melissa M.; Fu, Shanlin; Molnar, Anna; Lewis, John; Budney, Alan J.

    2012-01-01

    Background and Aims Questions over the clinical significance of cannabis withdrawal have hindered its inclusion as a discrete cannabis induced psychiatric condition in the Diagnostic and Statistical Manual of Mental Disorders (DSM IV). This study aims to quantify functional impairment to normal daily activities from cannabis withdrawal, and looks at the factors predicting functional impairment. In addition the study tests the influence of functional impairment from cannabis withdrawal on cannabis use during and after an abstinence attempt. Methods and Results A volunteer sample of 49 non-treatment seeking cannabis users who met DSM-IV criteria for dependence provided daily withdrawal-related functional impairment scores during a one-week baseline phase and two weeks of monitored abstinence from cannabis with a one month follow up. Functional impairment from withdrawal symptoms was strongly associated with symptom severity (p = 0.0001). Participants with more severe cannabis dependence before the abstinence attempt reported greater functional impairment from cannabis withdrawal (p = 0.03). Relapse to cannabis use during the abstinence period was associated with greater functional impairment from a subset of withdrawal symptoms in high dependence users. Higher levels of functional impairment during the abstinence attempt predicted higher levels of cannabis use at one month follow up (p = 0.001). Conclusions Cannabis withdrawal is clinically significant because it is associated with functional impairment to normal daily activities, as well as relapse to cannabis use. Sample size in the relapse group was small and the use of a non-treatment seeking population requires findings to be replicated in clinical samples. Tailoring treatments to target withdrawal symptoms contributing to functional impairment during a quit attempt may improve treatment outcomes. PMID:23049760

  7. Quantifying the clinical significance of cannabis withdrawal.

    Directory of Open Access Journals (Sweden)

    David J Allsop

    Full Text Available Questions over the clinical significance of cannabis withdrawal have hindered its inclusion as a discrete cannabis induced psychiatric condition in the Diagnostic and Statistical Manual of Mental Disorders (DSM IV. This study aims to quantify functional impairment to normal daily activities from cannabis withdrawal, and looks at the factors predicting functional impairment. In addition the study tests the influence of functional impairment from cannabis withdrawal on cannabis use during and after an abstinence attempt.A volunteer sample of 49 non-treatment seeking cannabis users who met DSM-IV criteria for dependence provided daily withdrawal-related functional impairment scores during a one-week baseline phase and two weeks of monitored abstinence from cannabis with a one month follow up. Functional impairment from withdrawal symptoms was strongly associated with symptom severity (p=0.0001. Participants with more severe cannabis dependence before the abstinence attempt reported greater functional impairment from cannabis withdrawal (p=0.03. Relapse to cannabis use during the abstinence period was associated with greater functional impairment from a subset of withdrawal symptoms in high dependence users. Higher levels of functional impairment during the abstinence attempt predicted higher levels of cannabis use at one month follow up (p=0.001.Cannabis withdrawal is clinically significant because it is associated with functional impairment to normal daily activities, as well as relapse to cannabis use. Sample size in the relapse group was small and the use of a non-treatment seeking population requires findings to be replicated in clinical samples. Tailoring treatments to target withdrawal symptoms contributing to functional impairment during a quit attempt may improve treatment outcomes.

  8. 19 CFR 144.36 - Withdrawal for transportation.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 2 2010-04-01 2010-04-01 false Withdrawal for transportation. 144.36 Section 144... § 144.36 Withdrawal for transportation. (a) Time limit. Merchandise may be withdrawn from warehouse for transportation to another port of entry if withdrawal for consumption or exportation can be accomplished at the...

  9. Gnome-Coach, New Mexico Site Fact Sheet

    International Nuclear Information System (INIS)

    2009-01-01

    The Gnome-Coach Site is located in southern Eddy County, New Mexico, 11 miles east of the Pecos River and 25 miles southeast of the city of Carlsbad. The site is approximately 680 acres. The land is currently withdrawn from all forms of disposition under the public land laws, including U.S. mining laws and leasing under mineral leasing laws. On December 10, 1961, a 3-kiloton-yield nuclear device was detonated at a depth of 1,183 feet below ground surface in a thick, bedded salt deposit within the Salado Formation.

  10. Biologic surveys for the Sandia National Laboratories, Coyote Canyon Test Complex, Kirtland Air Force Base, Albuquerque, New Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Sullivan, R.M. [4115 Allen Dr., Kingsville, TX (United States); Knight, P.J. [Marron and Associates, Inc., Corrales, NM (United States)

    1994-05-25

    This report provides results of a comprehensive biologic survey performed in Coyote Canyon Test Complex (CCTC), Sandia National Laboratories (SNL), Bernalillo County, New Mexico, which was conducted during the spring and summer of 1992 and 1993. CCTC is sited on land owned by the Department of Energy (DOE) and Kirtland Air Force Base and managed by SNL. The survey covered 3,760 acres of land, most of which is rarely disturbed by CCTC operations. Absence of grazing by livestock and possibly native ungulates, and relative to the general condition of private range lands throughout New Mexico, and relative to other grazing lands in central New Mexico. Widely dispersed, low intensity use by SNL as well as prohibition of grazing has probably contributed to abundance of special status species such as grama grass cactus within the CCTC area. This report evaluates threatened and endangered species found in the area, as well as comprehensive assessment of biologic habitats. Included are analyses of potential impacts and mitigative measures designed to reduce or eliminate potential impacts. Included is a summary of CCTC program and testing activities.

  11. Psychosis following Tramadol Withdrawal

    OpenAIRE

    Rajabizadeh, Ghodratolah; Kheradmand, Ali; Nasirian, Mansoureh

    2009-01-01

    Background: Tramadol is a centrally acting opioid analgesic used to treat moderate to sever pain. It has more advantage and less opioid adverse effects than conventional opioid analgesia. Case Report: This article reports a patient with tramadol dependency that had psychosis after tramadol withdrawal. Conclusion: By the increase of tramadol usage for relief of chronic pain, tramadol abuse and dependency is increased. Some of tramadol withdrawal symptoms are not related to opioid, for example ...

  12. Coexisting sea-based and land-based sources of contamination by PAHs in the continental shelf sediments of Coatzacoalcos River discharge area (Gulf of Mexico).

    Science.gov (United States)

    Ruiz-Fernández, Ana Carolina; Portela, Julián Mauricio Betancourt; Sericano, José Luis; Sanchez-Cabeza, Joan-Albert; Espinosa, Luisa Fernanda; Cardoso-Mohedano, José Gilberto; Pérez-Bernal, Libia Hascibe; Tinoco, Jesús Antonio Garay

    2016-02-01

    The oldest refinery and the major petrochemical complexes of Mexico are located in the lower reach of the Coatzacoalcos River, considered the most polluted coastal area of Mexico. A (210)Pb-dated sediment core, from the continental shelf of the Coatzacoalcos River, was studied to assess the contamination impact by the oil industry in the southern Gulf of Mexico. The sedimentary record showed the prevalence of petrogenic PAHs between 1950s and 1970s, a period during which waste discharges from the oil industry were not regulated. Later on, sediments exhibited higher contents of pyrogenic PAHs, attributed to the incineration of petrochemical industry wastes and recurrent wildfires in open dumpsites at the nearby swamps. The total concentration of the 16 EPA-priority PAHs indicated low levels of contamination (1000 ng g(-1)) during the late 1970s, most likely due to the major oil spill produced by the blowout of the Ixtoc-I offshore oil rig in deep waters of the southwestern Gulf of Mexico. Most of the PAH congeners did not show defined temporal trends but, according to a Factor Analysis, apparently have a common origin, probably waste released from the nearby oil industry. The only exceptions were the pyrogenic benzo(b)fluoranthene and benzo(a)pyrene, and the biogenic perylene, that showed increasing concentration trends with time, which we attributed to erosional input of contaminated soil from the catchment area. Our study confirmed chronic oil contamination in the Coatzacoalcos River coastal area from land based sources for more than 60 years (since 1950s). Copyright © 2015 Elsevier Ltd. All rights reserved.

  13. Predictors of withdrawal: possible precursors of avoidant personality disorder.

    Science.gov (United States)

    Eggum, Natalie D; Eisenberg, Nancy; Spinrad, Tracy L; Valiente, Carlos; Edwards, Alison; Kupfer, Anne S; Reiser, Mark

    2009-01-01

    Relations of avoidant personality disorder (AvPD) with shyness and inhibition suggest that a precursor of AvPD is withdrawal. Using a sample of 4.5- to 7-year-olds studied four times, 2 years apart, four and three classes of children differing in trajectories of mother- and teacher-reported withdrawal, respectively, were identified. Mothers and teachers generally did not agree on children's trajectories but the pattern of findings in the two contexts did not differ markedly. The mother-identified high and declining withdrawal class, in comparison with less withdrawn classes, and the teacher-identified high and declining class compared with low withdrawal classes, were associated with relatively high levels of anger and low levels of attentional control and resiliency. The mother-identified moderate and increasing withdrawal class was distinguished from less problematic withdrawal classes by higher anger, lower resiliency, and sometimes, lower attentional control. The teacher-identified low and increasing withdrawal class was distinguished from less problematic withdrawal classes by lower resiliency and lower attentional control. Findings are discussed in terms of the developmental precursors to social withdrawal and avoidant behavior.

  14. Investigation of land subsidence due to groundwater withdraw in Rafsanjan plain using GIS software

    International Nuclear Information System (INIS)

    Rahnama, M. B; Moafi H

    2009-01-01

    Nowadays, the purpose of predicting land subsidence is to manage the optimum usage of groundwater, which is considered according to irregular use of groundwater. Digging deep and semi-deep wells and continuous drought, mainly in wasteland and semi-wasteland zone in recent years causes the land subsidence in Rafsanjan plain. The Rafsanjan basin is located in the nearly central part of Iran in the Kerman province, with a general elevation between 1,400-1,500 m above sea level. In this research, first, the deep and semi-deep wells were investigated and groundwater table data were colleted. Second, these informations were analyzed and corrected. These data were used to create great bank of information data, to manage and program the geographic information system (GIS) software. Then by investigation of an existing land subsidence data, which were collected by GPS in August 1998 and April 1999, by the GIS software, the results show that discharging of groundwater is the main factor of the land subsidence in Rafsanjan zone. Therefore, the critical land subsidence zone of the Rafsanjan plain was determined, and precaution and recommendations are presented. (author)

  15. Buprenorphine for managing opioid withdrawal.

    Science.gov (United States)

    Gowing, Linda; Ali, Robert; White, Jason M; Mbewe, Dalitso

    2017-02-21

    Managed withdrawal is a necessary step prior to drug-free treatment or as the endpoint of substitution treatment. To assess the effects of buprenorphine versus tapered doses of methadone, alpha 2 -adrenergic agonists, symptomatic medications or placebo, or different buprenorphine regimens for managing opioid withdrawal, in terms of the intensity of the withdrawal syndrome experienced, duration and completion of treatment, and adverse effects. We searched the Cochrane Central Register of Controlled Trials (CENTRAL, Issue 11, 2016), MEDLINE (1946 to December week 1, 2016), Embase (to 22 December 2016), PsycINFO (1806 to December week 3, 2016), and the Web of Science (to 22 December 2016) and handsearched the reference lists of articles. Randomised controlled trials of interventions using buprenorphine to modify the signs and symptoms of withdrawal in participants who were primarily opioid dependent. Comparison interventions involved reducing doses of methadone, alpha 2 -adrenergic agonists (clonidine or lofexidine), symptomatic medications or placebo, and different buprenorphine-based regimens. We used standard methodological procedures expected by Cochrane. We included 27 studies involving 3048 participants. The main comparators were clonidine or lofexidine (14 studies). Six studies compared buprenorphine versus methadone, and seven compared different rates of buprenorphine dose reduction. We assessed 12 studies as being at high risk of bias in at least one of seven domains of methodological quality. Six of these studies compared buprenorphine with clonidine or lofexidine and two with methadone; the other four studies compared different rates of buprenorphine dose reduction.For the comparison of buprenorphine and methadone in tapered doses, meta-analysis was not possible for the outcomes of intensity of withdrawal or adverse effects. However, information reported by the individual studies was suggestive of buprenorphine and methadone having similar capacity to

  16. 20 CFR 408.355 - Can you withdraw your application?

    Science.gov (United States)

    2010-04-01

    ... Section 408.355 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SPECIAL BENEFITS FOR CERTAIN WORLD WAR II VETERANS Filing Applications Withdrawal of Application § 408.355 Can you withdraw your application? (a) Request for withdrawal filed before a determination is made. You may withdraw your application...

  17. Subsidence Induced Faulting Hazard risk maps in Mexico City and Morelia, central Mexico

    Science.gov (United States)

    Cabral-Cano, E.; Solano-Rojas, D.; Hernández-Espriu, J.; Cigna, F.; Wdowinski, S.; Osmanoglu, B.; Falorni, G.; Bohane, A.; Colombo, D.

    2012-12-01

    Subsidence and surface faulting have affected urban areas in Central Mexico for decades and the process has intensified as a consequence of urban sprawl and economic growth. This process causes substantial damages to the urban infrastructure and housing structures and in several cities it is becoming a major factor to be considered when planning urban development, land use zoning and hazard mitigation strategies in the next decades. Subsidence is usually associated with aggressive groundwater extraction rates and a general decrease of aquifer static level that promotes soil consolidation, deformation and ultimately, surface faulting. However, local stratigraphic and structural conditions also play an important role in the development and extension of faults. Despite its potential for damaging housing, and other urban infrastructure, the economic impact of this phenomena is poorly known, in part because detailed, city-wide subsidence induced faulting risk maps have not been published before. Nevertheless, modern remote sensing techniques are most suitable for this task. We present the results of a risk analysis for subsidence induced surface faulting in two cities in central Mexico: Morelia and Mexico City. Our analysis in Mexico City and Morelia is based on a risk matrix using the horizontal subsidence gradient from a Persistent Scatterer InSAR (Morelia) and SqueeSAR (Mexico City) analysis and 2010 census population distribution data from Mexico's National Institute of Statistics and Geography. Defining subsidence induced surface faulting vulnerability within these urbanized areas is best determined using both magnitude and horizontal subsidence gradient. Our Morelia analysis (597,000 inhabitants with localized subsidence rates up to 80 mm/yr) shows that 7% of the urbanized area is under a high to very high risk level, and 14% of its population (11.7% and 2.3% respectively) lives within these areas. In the case of the Mexico City (15'490,000 inhabitants for the

  18. MRS on Indian lands? Congress shuffles feet

    International Nuclear Information System (INIS)

    Hudson, M.

    1995-01-01

    This article discusses the political, social, and economic aspects of siting the Monitored Retrieval Storage (MRS) facility. The first focus is on siting in American Indian lands, specifically in Mescalero, New Mexico, followed by a more general discussion of the problems surrounding MRS siting

  19. 21 CFR 514.7 - Withdrawal of applications without prejudice.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Withdrawal of applications without prejudice. 514... Withdrawal of applications without prejudice. The sponsor may withdraw his pending application from.... Such withdrawal may be made without prejudice to a future filing. Upon resubmission, the time...

  20. Nicotine Withdrawal Induces Neural Deficits in Reward Processing.

    Science.gov (United States)

    Oliver, Jason A; Evans, David E; Addicott, Merideth A; Potts, Geoffrey F; Brandon, Thomas H; Drobes, David J

    2017-06-01

    Nicotine withdrawal reduces neurobiological responses to nonsmoking rewards. Insight into these reward deficits could inform the development of targeted interventions. This study examined the effect of withdrawal on neural and behavioral responses during a reward prediction task. Smokers (N = 48) attended two laboratory sessions following overnight abstinence. Withdrawal was manipulated by having participants smoke three regular nicotine (0.6 mg yield; satiation) or very low nicotine (0.05 mg yield; withdrawal) cigarettes. Electrophysiological recordings of neural activity were obtained while participants completed a reward prediction task that involved viewing four combinations of predictive and reward-determining stimuli: (1) Unexpected Reward; (2) Predicted Reward; (3) Predicted Punishment; (4) Unexpected Punishment. The task evokes a medial frontal negativity that mimics the phasic pattern of dopaminergic firing in ventral tegmental regions associated with reward prediction errors. Nicotine withdrawal decreased the amplitude of the medial frontal negativity equally across all trial types (p nicotine dependence (p Nicotine withdrawal had equivocal impact across trial types, suggesting reward processing deficits are unlikely to stem from changes in phasic dopaminergic activity during prediction errors. Effects on tonic activity may be more pronounced. Pharmacological interventions directly targeting the dopamine system and behavioral interventions designed to increase reward motivation and responsiveness (eg, behavioral activation) may aid in mitigating withdrawal symptoms and potentially improving smoking cessation outcomes. Findings from this study indicate nicotine withdrawal impacts reward processing signals that are observable in smokers' neural activity. This may play a role in the subjective aversive experience of nicotine withdrawal and potentially contribute to smoking relapse. Interventions that address abnormal responding to both pleasant and

  1. Vestas and the Indigenous Communities in Oaxaca, Mexico

    DEFF Research Database (Denmark)

    Ramirez, Jacobo

    2014-01-01

    in Mexico and were among the most experienced wind developers in the world, 'their capitalist model' failed to take into account, 'the spiritual and social ties between the indigenous rural communities and the land'. According to local residents, the basic problem was a clash of cultures. This case can...... and 40 indigenous Zapotec and Huave people held rallies in front of the Danish Embassy in Mexico City. With banners and placards, the protestors demanded Vestas’s exit from the Isthmus of Tehuantepec. The indigenous people suggested that although European companies had traditionally been present...... and stakeholder involvement between MNCs, governmental officials and local communities, when implementing large-scale investment projects. The case presents a conflict which involves four actors: 1) Indigenous communities in the Isthmus of Tehuantepec region in Oaxaca, Mexico: Zapotecas, Huaves or Ikoot, 2...

  2. Geology of Southern Quintana Roo (Mexico) and the Chicxulub Ejecta Blanket

    Science.gov (United States)

    Schönian, F.; Tagle, R.; Stöffler, D.; Kenkmann, T.

    2005-03-01

    In southern Quintana Roo (Mexico) the Chicxulub ejecta blanket is discontinuously filling a karstified pre-KT land surface. This suggests a completely new scenario for the geological evolution of the southern Yucatán Peninsula.

  3. Determinants of early withdrawal and of early withdrawal by reason of disability from the Irish labour force in the third age

    OpenAIRE

    Lawless, Martin

    2015-01-01

    III – Abstract: Determinants of early withdrawal and early withdrawal by reason of disability from the Irish labour force in the Third Age.Background. This study examines the relationship between early withdrawal and early withdrawal through disability from the Irish labour force in the Third Age. The relationship between unemployment or early retirement and ill health has been determined by a number of studies and, while unemployment through ill health or occupational disability may lead to ...

  4. 76 FR 72001 - Notice of Public Meeting, Albuquerque District Resource Advisory Council Meeting, New Mexico

    Science.gov (United States)

    2011-11-21

    ... management in New Mexico. Planned agenda items include a welcome and introduction of new Council members... DEPARTMENT OF THE INTERIOR Bureau of Land Management [LLNMA00000.L12200000.DF0000] Notice of... Management, Interior. ACTION: Notice of public meeting. SUMMARY: In accordance with the Federal Land Policy...

  5. 20 CFR 404.640 - Withdrawal of an application.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Withdrawal of an application. 404.640 Section 404.640 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Filing of Applications and Other Forms Withdrawal of Application § 404.640 Withdrawal of...

  6. 20 CFR 416.355 - Withdrawal of an application.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Withdrawal of an application. 416.355 Section 416.355 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Filing of Applications Withdrawal of Application § 416.355 Withdrawal of an...

  7. Withdrawal symptoms in internet gaming disorder: A systematic review.

    Science.gov (United States)

    Kaptsis, Dean; King, Daniel L; Delfabbro, Paul H; Gradisar, Michael

    2016-02-01

    Internet gaming disorder (IGD) is currently positioned in the appendix of the DSM-5 as a condition requiring further study. The aim of this review was to examine the state of current knowledge of gaming withdrawal symptomatology, given the importance of withdrawal in positioning the disorder as a behavioral addiction. A total of 34 studies, including 10 qualitative studies, 17 research reports on psychometric instruments, and 7 treatment studies, were evaluated. The results indicated that the available evidence on Internet gaming withdrawal is very underdeveloped. Internet gaming withdrawal is most consistently referred to as 'irritability' and 'restlessness' following cessation of the activity. There exists a concerning paucity of qualitative studies that provide detailed clinical descriptions of symptoms arising from cessation of internet gaming. This has arguably compromised efforts to quantify withdrawal symptoms in empirical studies of gaming populations. Treatment studies have not reported on the natural course of withdrawal and/or withdrawal symptom trajectory following intervention. It is concluded that many more qualitative clinical studies are needed, and should be prioritised, to develop our understanding of gaming withdrawal. This should improve clinical descriptions of problematic internet gaming and in turn improve the quantification of IGD withdrawal and thus treatments for harmful internet gaming. Copyright © 2015 Elsevier Ltd. All rights reserved.

  8. Application of InSAR and gravimetric surveys for developing construction codes in zones of land subsidence induced by groundwater extraction: case study of Aguascalientes, Mexico

    Directory of Open Access Journals (Sweden)

    J. Pacheco-Martínez

    2015-11-01

    Full Text Available Interferometric Synthetic Aperture Radar (InSAR has become a valuable tool for surface deformation monitoring, including land subsidence associated with groundwater extraction. Another useful tools for studying Earth's surface processes are geophysical methods such as Gravimetry. In this work we present the application of InSAR analysis and gravimetric surveying to generate valuable information for risk management related to land subsidence and surface faulting. Subsidence of the city of Aguascalientes, Mexico is presented as study case. Aguascalientes local governments have addressed land subsidence issues by including new requirements for new constructions projects in the State Urban Construction Code. Nevertheless, the resulting zoning proposed in the code is still subjective and not clearly defined. Our work based on gravimetric and InSAR surveys is aimed for improving the subsidence hazard zoning proposed in the State Urban Code in a more comprehensive way. The study includes a 2007–2011 ALOS InSAR time-series analysis of the Aguascalientes valley, an interpretation of the compete Bouguer gravimetric anomaly of the Aguascalientes urban area, and the application of time series and gravimetric anomaly maps for improve the subsidence hazard zoning of Aguascalientes City.

  9. SSRI and SNRI withdrawal symptoms reported on an internet forum.

    Science.gov (United States)

    Stockmann, Tom; Odegbaro, Dolapo; Timimi, Sami; Moncrieff, Joanna

    2018-05-09

    Antidepressant withdrawal symptoms are well-recognised, but their potential duration remains uncertain. We aimed to describe the characteristics of withdrawal associated with two popular classes of antidepressants, including duration. We analysed the content of a sample of posts on an antidepressant withdrawal website. We compared the characteristics of withdrawal associated with SSRIs and SNRIs, including time of onset, duration and nature of symptoms. 110 posts about SSRI withdrawal, and 63 concerning SNRI withdrawal, were analysed. The mean duration of withdrawal symptoms was significantly longer with SSRIs than SNRIs: 90.5 weeks (standard deviation, SD, 150.0) and 50.8 weeks (SD 76.0) respectively; p = 0.043). Neurological symptoms, such as 'brain zaps,' were more common among SNRI users (p = 0.023). Psychosexual/genitourinary symptoms may be more common among SSRI users (p = 0.054). The website aims to help people with antidepressant withdrawal, and is therefore likely to attract people who have difficulties. Length of prior use of antidepressants was long, with a mean of 252.2 weeks (SD 250.8). People accessing antidepressant withdrawal websites report experiencing protracted withdrawal symptoms. There are some differences in the characteristics of withdrawal associated with different classes of antidepressants.

  10. The Non-Proliferation Treaty and the Withdrawal Clause

    International Nuclear Information System (INIS)

    Boutherin, Gregory

    2008-01-01

    Like any international agreement, the NPT includes a withdrawal clause. The North Korean withdrawal, which was announced in 1993 and became effective in 2003, shows how difficult it is to preserve this possibility, while guaranteeing compliance with signed agreements. To achieve this target, two conditions are required: first, enhancing the means by which the reasons for withdrawals can be made clear and second, to allow the Security Council to draw all the consequences of withdrawals that could imply that a treaty has been violated

  11. Withdrawal-oriented therapy for smokers.

    Science.gov (United States)

    Hajek, P

    1989-06-01

    The treatment approach of the Maudsley Hospital Smokers Clinic is described. It stems from the notion that smokers seeking help are dependent on nicotine, and that withdrawal discomfort is a major block to their success in quitting. Accordingly, therapy focuses on helping clients overcome nicotine deprivation. It uses nicotine replacement and a special format of group treatment. Details are given of preparation of clients, use of nicotine chewing gum, use of group-oriented groupwork, use of information about withdrawal, and training in withdrawal-oriented therapy. Data are presented concerning characteristics of the clientele, treatment adherence, and treatment results. A number of controversial issues are addressed, such as the optimal duration of treatment, timing of the quit date, the value of educational input, and the value of individualization of treatment goals.

  12. Water resources during drought conditions and postfire water quality in the upper Rio Hondo Basin, Lincoln County, New Mexico, 2010-13

    Science.gov (United States)

    Sherson, Lauren R.; Rice, Steven E.

    2015-07-16

    Stakeholders and water-resource managers in Lincoln County, New Mexico, have had long-standing concerns over the impact of population growth and groundwater withdrawals. These concerns have been exacerbated in recent years by extreme drought conditions and two major wildfires in the upper Rio Hondo Basin, located in south-central New Mexico. The U.S. Geological Survey (USGS), in cooperation with Lincoln County, initiated a study in 2006 to assess and characterize water resources in the upper Rio Hondo Basin. Data collected during water years 2010–13 are presented and interpreted in this report. All data presented in this report are described in water years unless stated otherwise.

  13. Land-Use and Land-Cover Change around Mobile Bay, Alabama from 1974-2008

    Science.gov (United States)

    Ellis, Jean; Spruce, Joseph P.; Swann, Roberta; Smooth, James C.

    2009-01-01

    This document summarizes the major findings of a Gulf of Mexico Application Pilot project led by NASA Stennis Space Center (SSC) in conjunction with a regional collaboration network of the Gulf of Mexico Alliance (GOMA). NASA researchers processed and analyzed multi-temporal Landsat data to assess land-use and land-cover (LULC) changes in the coastal counties of Mobile and Baldwin, AL between 1974 and 2008. Our goal was to create satellite-based LULC data products using methods that could be transferable to other coastal areas of concern within the Gulf of Mexico. The Mobile Bay National Estuary Program (MBNEP) is the primary end-user, however, several other state and local groups may benefit from the project s data products that will be available through NOAA-NCDDC s Regional Ecosystem Data Management program. Mobile Bay is a critical ecologic and economic region in the Gulf of Mexico and to the entire country. Mobile Bay was designated as an estuary of national significance in 1996. This estuary receives the fourth largest freshwater inflow in the United States. It provides vital nursery habitat for commercially and recreationally important fish species. It has exceptional aquatic and terrestrial bio-diversity, however, its estuary health is influenced by changing LULC patterns, such as urbanization. Mobile and Baldwin counties have experienced a population growth of 1.1% and 20.5% from 2000-2006. Urban expansion and population growth are likely to accelerate with the construction and operation of the ThyssenKrupp steel mill in the northeast portion of Mobile County. Land-use and land-cover change can negatively impact Gulf coast water quality and ecological resources. The conversion of forest to urban cover types impacts the carbon cycle and increases the freshwater and sediment in coastal waters. Increased freshwater runoff decreases salinity and increases the turbidity of coastal waters, thus impacting the growth potential of submerged aquatic vegetation (SAV

  14. The electric energy and the environment in Mexico. Volume 3; Energia electrica y medio ambiente en Mexico. Volumen 3

    Energy Technology Data Exchange (ETDEWEB)

    Quintanilla Martinez, Juan [eds.] [Universidad Nacional Autonoma de Mexico, Mexico, D. F. (Mexico)

    1997-12-31

    This document is the third one of three volumes of the 1. Seminar on the Current Conditions and Perspectives of the Electric Sector in Mexico, organized by the Programa Universitario de Energia and the Instituto de Investigaciones Economicas (University Program of Energy and the Institute of Economic Research), both of them agencies of the Universidad Autonoma de Mexico (UNAM). The titles of the three volumes are the following: Volume 1.- The opening of the Mexican Electric Sector to foreign investment. Volume 2.- Concrete innovation and technological learning experiences at the Luz y Fuerza del Centro enterprise. Volume 3.- The Electric Energy and the Environment in Mexico. This third volume covers the following subjects: Hydroelectricity, land use and water managing; the electric generation in Mexico and its environmental impact, the nuclear electricity and the handling of radioactive materials; the exposure to electromagnetic fields and its association with children`s leukemia; the energy in Mexico and the sustainable development; potential of electricity generation in large scale with wind power in Mexico; towards a scheme of distributed electric power generation with non-conventional energies and renewable energy sources in Mexico in the 21Century. These documents were elaborated by specialists of the electric sector, from the sector itself as well as from private and public academic entities [Espanol] Este documento constituye el tercero de tres volumenes del Primer Seminario sobre Situacion y Perspectivas del Sector Electrico en Mexico, organizado por el Programa Universitario de Energia y el Instituto de Investigaciones Economicas, ambas dependencias de la Universidad Nacional Autonoma de Mexico (UNAM). Los titulos de los tres volumenes son los siguientes: volumen 1: La apertura externa del sector electrico mexicano, volumen 2: Experiencias concretas de innovacion y aprendizaje tecnologico en la empresa Luz y Fuerza del Centro, volumen 3: Energia electrica

  15. Water Withdrawals, Use, and Trends in Florida, 2005

    Science.gov (United States)

    Marella, Richard L.

    2009-01-01

    In 2005, the total amount of water withdrawals in Florida was estimated at 18,359 million gallons per day (Mgal/d). Saline water accounted for 11,486 Mgal/d (63 percent), and freshwater accounted for 6,873 Mgal/d (37 percent). Groundwater accounted for 4,247 Mgal/d (62 percent) of freshwater withdrawals, and surface water accounted for the remaining 2,626 Mgal/d (38 percent). Surface water accounted for nearly all (99.9 percent) saline-water withdrawals. An additional 660 Mgal/d of reclaimed wastewater was used in Florida during 2005. The largest amount of freshwater was withdrawn from Palm Beach County, and the largest amount of saline water was withdrawn from Pasco County. Fresh groundwater provided drinking water (public supplied and self-supplied) for 16.19 million people (90 percent of Florida's population), and fresh surface water provided drinking water for 1.73 million people (10 percent). The majority of groundwater withdrawals (nearly 60 percent) in 2005 was obtained from the Floridan aquifer system which is present throughout the entire State. The majority of fresh surface-water withdrawals (59 percent) came from the southern Florida hydrologic unit subregion and is associated with Lake Okeechobee and the canals in the Everglades Agricultural Area of Glades, Hendry, and Palm Beach Counties, as well as the Caloosahatchee River and its tributaries in the agricultural areas of Collier, Glades, Hendry, and Lee Counties. Overall, agricultural irrigation accounted for 40 percent of the total freshwater withdrawals (ground and surface), followed by public supply with 37 percent. Public supply accounted for 52 percent of groundwater withdrawals, followed by agricultural self-supplied (31 percent), ommercial-industrial-mining self-supplied (8.5 percent), recreational irrigation and domestic self-supplied (4 percent each), and power generation (0.5 percent). Agricultural self-supplied accounted for 56 percent of fresh surface-water withdrawals, followed by power

  16. Opiate Withdrawal Complicated by Tetany and Cardiac Arrest

    Directory of Open Access Journals (Sweden)

    Irfanali R. Kugasia

    2014-01-01

    Full Text Available Patients with symptoms of opiate withdrawal, after the administration of opiate antagonist by paramedics, are a common presentation in the emergency department of hospitals. Though most of opiate withdrawal symptoms are benign, rarely they can become life threatening. This case highlights how a benign opiate withdrawal symptom of hyperventilation led to severe respiratory alkalosis that degenerated into tetany and cardiac arrest. Though this patient was successfully resuscitated, it is imperative that severe withdrawal symptoms are timely identified and immediate steps are taken to prevent catastrophes. An easier way to reverse the severe opiate withdrawal symptom would be with either low dose methadone or partial opiate agonists like buprenorphine. However, if severe acid-base disorder is identified, it would be safer to electively intubate these patients for better control of their respiratory and acid-base status.

  17. 78 FR 53780 - Notice of Realty Action: Direct Sale of Public Land in Doña Ana County, NM

    Science.gov (United States)

    2013-08-30

    ... Do[ntilde]a Ana County, New Mexico. The public land would be sold to the Union Pacific Railroad for $11,000 which is more than the appraised fair market value. DATES: Written comments regarding the... as follows: New Mexico Principal Meridian, New Mexico T. 28 S., R. 2 E., Sec. 11, lot 2; Sec. 14, lot...

  18. The alcohol withdrawal syndrome.

    LENUS (Irish Health Repository)

    McKeon, A

    2008-08-01

    The alcohol withdrawal syndrome (AWS) is a common management problem in hospital practice for neurologists, psychiatrists and general physicians alike. Although some patients have mild symptoms and may even be managed in the outpatient setting, others have more severe symptoms or a history of adverse outcomes that requires close inpatient supervision and benzodiazepine therapy. Many patients with AWS have multiple management issues (withdrawal symptoms, delirium tremens, the Wernicke-Korsakoff syndrome, seizures, depression, polysubstance abuse, electrolyte disturbances and liver disease), which requires a coordinated, multidisciplinary approach. Although AWS may be complex, careful evaluation and available treatments should ensure safe detoxification for most patients.

  19. 42 CFR 457.170 - Withdrawal process.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Withdrawal process. 457.170 Section 457.170 Public... Plans for Child Health Insurance Programs and Outreach Strategies § 457.170 Withdrawal process. (a... amendment, or any portion of a proposed State plan or plan amendment, at any time during the review process...

  20. Effect of Morphine Withdrawal Syndrome on Cerebral Ischemia

    Directory of Open Access Journals (Sweden)

    Mohammad Allahtavakoli

    2011-01-01

    Full Text Available Objective(sOpioid abuse is still remained a major mental health problem, a criminal legal issue and may cause ischemic brain changes including stroke and brain edema. In the present study, we investigated whether spontaneously withdrawal syndrome might affect stroke outcomes.Materials and MethodsAddiction was induced by progressive incremental doses of morphine over 7 days. Behavioral signs of withdrawal were observed 24, 48 and 72 hr after morphine deprivation and total withdrawal score was determined. Cerebral ischemia was induced 18-22 hr after the last morphine injection by placing a natural clot into the middle cerebral artery (MCA. Neurological deficits were evaluated at 2, 24 and 48 hr after ischemia induction, and infarct size and brain edema were determined at 48 hr after stroke.ResultsMorphine withdrawal animals showed a significant increase in total withdrawal score and decrease of weight gain during the 72 hr after the last morphine injection. Compared to the addicted and control animals, infarct volume and brain edema were significantly increased in the morphine deprived animals (P< 0.05 at 48 hr after cerebral ischemia. Also, neurological deficits were higher in the morphine-withdrawn rats at 48 hr after stroke (P< 0.05. ConclusionOur data indicates that spontaneous withdrawal syndrome may worsen stroke outcomes. Further investigations are necessary to elucidate mechanisms of opiate withdrawal syndrome on stroke.

  1. Mitragynine attenuates withdrawal syndrome in morphine-withdrawn zebrafish.

    Directory of Open Access Journals (Sweden)

    Beng-Siang Khor

    Full Text Available A major obstacle in treating drug addiction is the severity of opiate withdrawal syndrome, which can lead to unwanted relapse. Mitragynine is the major alkaloid compound found in leaves of Mitragyna speciosa, a plant widely used by opiate addicts to mitigate the harshness of drug withdrawal. A series of experiments was conducted to investigate the effect of mitragynine on anxiety behavior, cortisol level and expression of stress pathway related genes in zebrafish undergoing morphine withdrawal phase. Adult zebrafish were subjected to two weeks chronic morphine exposure at 1.5 mg/L, followed by withdrawal for 24 hours prior to tests. Using the novel tank diving tests, we first showed that morphine-withdrawn zebrafish display anxiety-related swimming behaviors such as decreased exploratory behavior and increased erratic movement. Morphine withdrawal also elevated whole-body cortisol levels, which confirms the phenotypic stress-like behaviors. Exposing morphine-withdrawn fish to mitragynine however attenuates majority of the stress-related swimming behaviors and concomitantly lower whole-body cortisol level. Using real-time PCR gene expression analysis, we also showed that mitragynine reduces the mRNA expression of corticotropin releasing factor receptors and prodynorphin in zebrafish brain during morphine withdrawal phase, revealing for the first time a possible link between mitragynine's ability to attenuate anxiety during opiate withdrawal with the stress-related corticotropin pathway.

  2. Developing a methodology for real-time trading of water withdrawal and waste load discharge permits in rivers.

    Science.gov (United States)

    Soltani, Maryam; Kerachian, Reza

    2018-04-15

    In this paper, a new methodology is proposed for the real-time trading of water withdrawal and waste load discharge permits in agricultural areas along the rivers. Total Dissolved Solids (TDS) is chosen as an indicator of river water quality and the TDS load that agricultural water users discharge to the river are controlled by storing a part of return flows in some evaporation ponds. Available surface water withdrawal and waste load discharge permits are determined using a non-linear multi-objective optimization model. Total available permits are then fairly reallocated among agricultural water users, proportional to their arable lands. Water users can trade their water withdrawal and waste load discharge permits simultaneously, in a bilateral, step by step framework, which takes advantage of differences in their water use efficiencies and agricultural return flow rates. A trade that would take place at each time step results in either more benefit or less diverted return flow. The Nucleolus cooperative game is used to redistribute the benefits generated through trades in different time steps. The proposed methodology is applied to PayePol region in the Karkheh River catchment, southwest Iran. Predicting that 1922.7 Million Cubic Meters (MCM) of annual flow is available to agricultural lands at the beginning of the cultivation year, the real-time optimization model estimates the total annual benefit to reach 46.07 million US Dollars (USD), which requires 6.31 MCM of return flow to be diverted to the evaporation ponds. Fair reallocation of the permits, changes these values to 35.38 million USD and 13.69 MCM, respectively. Results illustrate the effectiveness of the proposed methodology in the real-time water and waste load allocation and simultaneous trading of permits. Copyright © 2018 Elsevier Ltd. All rights reserved.

  3. DISCUSSION OF PLANNING AND IMPLEMENTATION OF GOVERNMENT AND PRIVATE AGENCY PROGRAMS IN NORTHERN NEW MEXICO.

    Science.gov (United States)

    KNOWLTON, CLARK S.

    THE MEXICAN AMERICAN POPULATION IN NORTHERN NEW MEXICO ORIGINALLY HAD LAND GRANTS FROM THE SPANISH CROWN. LACK OF UNDERSTANDING OR ACCEPTANCE OF THE AMERICAN SYSTEM OF INDIVIDUAL OWNERSHIP HAS CAUSED THE MEXICAN AMERICAN TO LOSE MUCH OF THE ORIGINAL GRANT LANDS. THE MEXICAN AMERICAN SOCIAL ORGANIZATION, ORIGINALLY STRUCTURED UPON THE FARM VILLAGE,…

  4. Environmental neglect that fuels migration. Regional report 3: Mexico.

    Science.gov (United States)

    1994-01-01

    This article reports the impact of environmental neglect on the Mexican population. Despite its participation in the Organization for Economic Cooperation and Development, Mexico is experiencing an environmental crisis. Being the first developing country to engage in the Green Revolution during the 1950s, the country experienced a four-fold increase in grain production. The population increased rapidly from 27 million to 92 million in the 1990s. Due to the increase in population and because the government was too preoccupied with its economic endeavors, the environment suffered, which in a way counteracted the benefits of the Green Revolution. Furthermore, environmental degradation (like loss of forests, less water supply to agricultural lands) had a chain effect. Large farmers engaging in capital-intensive cash cropping for export are buying out small farmers, which leads to many landless or near-landless peasants. Also, many marginalized farmers have long been forced to migrate into marginal lands. Because of the increase in migration in addition to the present population of 92 million, Mexico is showing inadequacy in securing food, employment, and houses. A realistic prognosis is that many Mexicans in the year 2000 could be poorer than they were in 1985; but with the help of the NAFTA free-trade zone, Mexico is hopeful to increase its employment opportunities and reverse its present situation.

  5. Withdrawing to a Virtual World: Associations between Subtypes of Withdrawal, Media Use, and Maladjustment in Emerging Adults

    Science.gov (United States)

    Nelson, Larry J.; Coyne, Sarah M.; Howard, Emily; Clifford, Brandon N.

    2016-01-01

    An approach-avoidance model of social withdrawal (Asendorpf, 1990) identifies 3 types of social withdrawal including shyness, unsociability, and avoidance. Each appears to be uniquely associated with varying indicators of maladjustment in emerging adulthood (Nelson, 2013) but little, if any, work has been done to see how they might be linked to…

  6. An overview of research on social withdrawal in childhood

    OpenAIRE

    野村, あすか; NOMURA, Asuka

    2013-01-01

    In recent years, “HIKIKOMORI” in adolescence or adulthood has grown into a serious problem in Japan and the need for early intervention and support has been emphasized. Among the risk factors of “HIKIKOMORI” is social withdrawal in childhood. With this in mind, I reviewed previous studies on the social withdrawal in children living abroad. The review commences with an examination of definitions of social withdrawal, which showed that in some foreign countries, social withdrawal refers to the ...

  7. Mexico Financial Sector Assessment Program : Housing Finance

    OpenAIRE

    World Bank Group; International Finance Corporation

    2016-01-01

    Housing needs are high in Mexico despite quantitative progress in the last 10 years.Global data hide mismatches between housing demand and supply. First, urban growth relied for a long time on a pattern of urban sprawl, with mass-scale developments of individual units were built outside cities where land is affordable, but far from jobs and services and with related high transportation cos...

  8. Why withdrawal from the European Union is undemocratic

    DEFF Research Database (Denmark)

    Olsen, Tore Vincents; Rostbøll, Christian F.

    2017-01-01

    The Lisbon Treaty from 2009 introduced the possibility for individual member states to withdraw from the European Union (EU) on the basis of a unilateral decision. In June 2016 the UK decided to leave the EU invoking article 50 of the treaty. But is withdrawal democratically legitimate? In fact......, the all affected principle suggests that it is undemocratic for subunits to leave larger political units when it adversely affects other citizens without including them in the decision. However, it is unclear what the currency of this affectedness is and, hence, why withdrawal would be undemocratic. We...... argue that it is the effect of withdrawal on the status of citizens as free and equal that is decisive and that explains why unilateral withdrawal of subunits from larger units is democratically illegitimate. Moreover, on the ‘all affected status principle’ that we develop, even multilaterally agreed...

  9. SITUATION OF THE SPANISH AMERICANS OF NORTHERN NEW MEXICO.

    Science.gov (United States)

    KNOWLTON, CLARK S.

    THE SPANISH AMERICANS OF NORTHERN NEW MEXICO HAVE CONSTITUTED ONE OF THE UNRECOGNIZED DISADVANTAGED GROUPS. PER CAPITA INCOME IS LOW AND THE RATES OF UNEMPLOYMENT AND WELFARE ARE HIGH. THE CAUSES OF THE PRESENT SITUATION ARE--(1) LOSS OF LAND, (2) CULTURAL AND LINGUISTIC DISCRIMINATORY ATTITUDES, (3) NON-PROVISION OF ADEQUATE PROGRAMS TO…

  10. Climate, water use, and land surface transformation in an irrigation intensive watershed - streamflow responses from 1950 through 2010

    Science.gov (United States)

    Dale, Joseph; Zou, Chris B.; Andrews, William J.; Long, James M.; Liang, Ye; Qiao, Lei

    2015-01-01

    Climatic variability and land surface change have a wide range of effects on streamflow and are often difficult to separate. We analyzed long-term records of climate, land use and land cover, and re-constructed the water budget based on precipitation, groundwater levels, and water use from 1950 through 2010 in the Cimarron–Skeleton watershed and a portion of the Cimarron–Eagle Chief watershed in Oklahoma, an irrigation-intensive agricultural watershed in the Southern Great Plains, USA. Our results show that intensive irrigation through alluvial aquifer withdrawal modifies climatic feedback and alters streamflow response to precipitation. Increase in consumptive water use was associated with decreases in annual streamflow, while returning croplands to non-irrigated grasslands was associated with increases in streamflow. Along with groundwater withdrawal, anthropogenic-induced factors and activities contributed nearly half to the observed variability of annual streamflow. Streamflow was more responsive to precipitation during the period of intensive irrigation between 1965 and 1984 than the period of relatively lower water use between 1985 and 2010. The Cimarron River is transitioning from a historically flashy river to one that is more stable with a lower frequency of both high and low flow pulses, a higher baseflow, and an increased median flow due in part to the return of cropland to grassland. These results demonstrated the interrelationship among climate, land use, groundwater withdrawal and streamflow regime and the potential to design agricultural production systems and adjust irrigation to mitigate impact of increasing climate variability on streamflow in irrigation intensive agricultural watershed.

  11. GoMRC Website ‘Meta-analysis Report: Land-use and submerged aquatic vegetation change in the Gulf of Mexico’

    Energy Technology Data Exchange (ETDEWEB)

    Judd, Chaeli; Stefansson, Emily S.; Brushnahan, Heather

    2007-12-06

    Over the past century, health and spatial extent of seagrasses has decreased dramatically in the Gulf of Mexico. While some of the changes can be explained by direct impacts to the seagrass beds, we hypothesize that changes in the land use in the watersheds can also be correlated with the decline of seagrasses. Through this meta-analysis, we researched historical and compared trends in seagrass populations and land use in five bays and their watersheds within the Gulf of Mexico: Mobile Bay, Perdido Bay, Tampa Bay, Charlotte Harbor, and Galveston Bay. Using both historical records and spatial datasets, we examined land use and seagrass trends in these five areas.

  12. PES Impact and Leakages over Several Cohorts: The Case of PSA-H in Yucatan, Mexico

    OpenAIRE

    LE VELLY , Gwenole; Sauquet , Alexandre; CORTINA-VILLAR , Sergio

    2015-01-01

    We assess the impact of a payment for environmental services scheme implemented in Mexico, the PSA-H, over the 2005-2012 period. By studying several cohorts of program beneficiaries we are able to shed lights on the permanence of the program's impact. Based on the exploitation of 2.5 to 20m resolution SPOT images and ejido-surveys carried out in 76 ejidos located in the Cono Sur of Yucatan, we find that the program's effects are cancelled after communities choose to withdraw from the program,...

  13. 15 CFR 10.13 - Withdrawal of a published standard.

    Science.gov (United States)

    2010-01-01

    ...) Before withdrawing a standard published under these procedures, the Director will review the relative... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Withdrawal of a published standard. 10... DEVELOPMENT OF VOLUNTARY PRODUCT STANDARDS § 10.13 Withdrawal of a published standard. (a) Standards published...

  14. A high-resolution land-use map; Nogales, Sonora, Mexico

    Science.gov (United States)

    Norman, Laura M.; Villarreal, Miguel L.; Wallace, Cynthia S.A.; Gil Anaya, Claudia Z.; Diaz Arcos, Israel; Gray, Floyd

    2010-01-01

    The cities of Nogales, Sonora, and Nogales, Arizona, are located in the Ambos Nogales Watershed, a topographically irregular bowl-shaped area with a northward gradient. Throughout history, residents in both cities have been affected by flooding. Currently, the primary method for regulating this runoff is to build a series of detention basins in Nogales, Sonora. Additionally, the municipality also is considering land-use planning to help mitigate flooding. This paper describes the production of a 10-meter resolution land-use map, derived from 2008 aerial photos of the Nogales, Sonora Watershed for modeling impacts of the detention basin construction and in support of an ?Early Warning Hazard System? for the region.

  15. Demand-Withdraw Patterns in Marital Conflict in the Home.

    Science.gov (United States)

    Papp, Lauren M; Kouros, Chrystyna D; Cummings, E Mark

    2009-06-01

    The present study extended laboratory-based findings of demand-withdraw communication into marital conflict in the home and further explored its linkages with spousal depression. U.S. couples (N = 116) provided diary reports of marital conflict and rated depressive symptoms. Hierarchical linear modeling results indicated that husband demand-wife withdraw and wife demand-husband withdraw occurred in the home at equal frequency, and both were more likely to occur when discussing topics that concerned the marital relationship. For both patterns, conflict initiator was positively linked to the demander role. Accounting for marital satisfaction, both demand-withdraw patterns predicted negative emotions and tactics during marital interactions and lower levels of conflict resolution. Spousal depression was linked to increased likelihood of husband demand-wife withdraw.

  16. 75 FR 7526 - Withdrawal of Regulatory Guide

    Science.gov (United States)

    2010-02-19

    ...'s Electronic Reading Room at http://www.nrc.gov/reading-rm/doc-collections . Regulatory guides are... NUCLEAR REGULATORY COMMISSION [NRC-2010-0052] Withdrawal of Regulatory Guide AGENCY: Nuclear Regulatory Commission. ACTION: Withdrawal of Regulatory Guide 1.56, ``Maintenance of Water Purity in Boiling...

  17. Remembering the Atomic Bomb in its Birthplace, New Mexico

    OpenAIRE

    Genay, Lucie

    2017-01-01

    On July 16, 1945 the « Land of Enchantment » acquired a new identity as the cradle of the nuclear age when the world’s first atomic bomb exploded in the Jornada del Muerto desert. New Mexico underwent a phenomenal transformation as a result of the arrival of atomic science in its remotest lands. The Trinity date does not hold the same place in collective memory as Hiroshima and Nagasaki but its historical significance takes various shapes on different memory scales. Therefore, this article ad...

  18. Rapid assessment of endemic bird areas in Michoacan, Mexico

    Science.gov (United States)

    Gilberto Chavez-Leon; Deborah M. Finch

    1999-01-01

    Non-sustainable land use practices in the state of Michoacan, Mexico, have perturbed endemic bird h~bitats for several decades. Endemic birds have a restricted geographic and ecological distribution. This feature makes them suitable to be used as indicators of biological diversity and environmental perturbation. Forty-one Mexican endemic species have been recorded in...

  19. Acupuncture for alcohol withdrawal: a randomized controlled trial.

    Science.gov (United States)

    Trümpler, François; Oez, Suzan; Stähli, Peter; Brenner, Hans Dieter; Jüni, Peter

    2003-01-01

    Previous trials on acupuncture in alcohol addiction were in outpatients and focused on relapse prevention. Rates of dropout were high and interpretation of results difficult. We compared auricular laser and needle acupuncture with sham laser stimulation in reducing the duration of alcohol withdrawal. Inpatients undergoing alcohol withdrawal were randomly allocated to laser acupuncture (n = 17), needle acupuncture (n = 15) or sham laser stimulation (n = 16). Attempts were made to blind patients, therapists and outcome assessors, but this was not feasible for needle acupuncture. The duration of withdrawal symptoms (as assessed using a nurse-rated scale) was the primary outcome; the duration of sedative prescription was the secondary outcome. Patients randomized to laser and sham laser had identical withdrawal symptom durations (median 4 days). Patients randomized to needle stimulation had a shorter duration of withdrawal symptoms (median 3 days; P = 0.019 versus sham intervention), and tended to have a shorter duration of sedative use, but these differences diminished after adjustment for baseline differences. The data from this pilot trial do not suggest a relevant benefit of auricular laser acupuncture for alcohol withdrawal. A larger trial including adequate sham interventions is needed, however, to reliably determine the effectiveness of any type of auricular acupuncture in this condition.

  20. 45 CFR 400.301 - Withdrawal from the refugee program.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Withdrawal from the refugee program. 400.301... Waivers and Withdrawals § 400.301 Withdrawal from the refugee program. (a) In the event that a State... assistance, social services, preventive health, and an unaccompanied minors program if appropriate. A State...

  1. Forecasting summertime surface temperature and precipitation in the Mexico City metropolitan area: sensitivity of the WRF model to land cover changes

    Science.gov (United States)

    López-Bravo, Clemente; Caetano, Ernesto; Magaña, Víctor

    2018-02-01

    Changes in the frequency and intensity of severe hydrometeorological events in recent decades in the Mexico City Metropolitan Area have motivated the development of weather warning systems. The weather forecasting system for this region was evaluated in sensitivity studies using the Weather Research and Forecasting Model (WRF) for July 2014, a summer time month. It was found that changes in the extent of the urban area and associated changes in thermodynamic and dynamic variables have induced local circulations that affect the diurnal cycles of temperature, precipitation, and wind fields. A newly implemented configuration (land cover update and Four-Dimensional Data Assimilation (FDDA)) of the WRF model has improved the adjustment of the precipitation field to the orography. However, errors related to the depiction of convection due to parameterizations and microphysics remains a source of uncertainty in weather forecasting in this region.

  2. Effect of Potassium Channel Modulators on Morphine Withdrawal in Mice

    Directory of Open Access Journals (Sweden)

    Vikas Seth

    2010-01-01

    Full Text Available The present study was conducted to investigate the effect of potassium channel openers and blockers on morphine withdrawal syndrome. Mice were rendered dependent on morphine by subcutaneous injection of morphine; four hours later, withdrawal was induced by using an opioid antagonist, naloxone. Mice were observed for 30 minutes for the withdrawal signs ie, the characteristic jumping, hyperactivity, urination and diarrhea. ATP-dependent potassium (K + ATP channel modulators were injected intraperitoneally (i.p. 30 minutes before the naloxone. It was found that a K + ATP channel opener, minoxidil (12.5–50 mg/kg i.p., suppressed the morphine withdrawal significantly. On the other hand, the K + ATP channel blocker glibenclamide (12.5–50 mg/kg i.p. caused a significant facilitation of the withdrawal. Glibenclamide was also found to abolish the minoxidil's inhibitory effect on morphine withdrawal. The study concludes that K + ATP channels play an important role in the genesis of morphine withdrawal and K + ATP channel openers could be useful in the management of opioid withdrawal. As morphine opens K + ATP channels in neurons, the channel openers possibly act by mimicking the effects of morphine on neuronal K + currents.

  3. Assessments of aquifer sensitivity on Navajo Nation and adjacent lands and ground-water vulnerability to pesticide contamination on the Navajo Indian Irrigation Project, Arizona, New Mexico, and Utah

    Science.gov (United States)

    Blanchard, Paul J.

    2002-01-01

    The U.S. Environmental Protection Agency requested that the Navajo Nation conduct an assessment of aquifer sensitivity on Navajo Nation lands and an assessment of ground-water vulnerability to pesticide contamination on the Navajo Indian Irrigation Project. Navajo Nation lands include about 17,000 square miles in northeastern Arizona, northwestern New Mexico, and southeastern Utah. The Navajo Indian Irrigation Project in northwestern New Mexico is the largest area of agriculture on the Navajo Nation. The Navajo Indian Irrigation Project began operation in 1976; presently (2001) about 62,000 acres are available for irrigated agriculture. Numerous pesticides have been used on the Navajo Indian Irrigation Project during its operation. Aquifer sensitivity is defined by the U.S. Environmental Protection Agency as 'The relative ease with which a contaminant [pesticide] applied on or near a land surface can migrate to the aquifer of interest. Aquifer sensitivity is a function of the intrinsic characteristics of the geologic material in question, any underlying saturated materials, and the overlying unsaturated zone. Sensitivity is not dependent on agronomic practices or pesticide characteristics.' Ground-water vulnerability is defined by the U.S. Environmental Protection Agency as 'The relative ease with which a contaminant [pesticide] applied on or near a land surface can migrate to the aquifer of interest under a given set of agronomic management practices, pesticide characteristics, and aquifer sensitivity conditions.' The results of the aquifer sensitivity assessment on Navajo Nation and adjacent lands indicated relative sensitivity within the boundaries of the study area. About 22 percent of the study area was not an area of recharge to bedrock aquifers or an area of unconsolidated deposits and was thus assessed to have an insignificant potential for contamination. About 72 percent of the Navajo Nation study area was assessed to be in the categories of most potential

  4. A psychometric validation of the Short Alcohol Withdrawal Scale (SAWS)

    DEFF Research Database (Denmark)

    Elholm, Bjarne; Larsen, Klaus; Hornnes, Nete

    2010-01-01

    The study aimed to evaluate psychometrically a Danish translation of the Short Alcohol Withdrawal Scale (SAWS) in an outpatient setting in patients with Alcohol Dependence (AD) and Alcohol Withdrawal Symptoms/Syndrome (AWS).......The study aimed to evaluate psychometrically a Danish translation of the Short Alcohol Withdrawal Scale (SAWS) in an outpatient setting in patients with Alcohol Dependence (AD) and Alcohol Withdrawal Symptoms/Syndrome (AWS)....

  5. [The effect of palonosetron on rocuronium-induced withdrawal movement].

    Science.gov (United States)

    Park, Ki-Bum; Jeon, Younghoon; Yi, Junggu; Kim, Ji-Hyun; Chung, Seung-Yeon; Kwak, Kyung-Hwa

    Rocuronium causes pain and withdrawal movement during induction of anesthesia. In this study, palonosetron was investigated to have analgesic effect on the reduction of rocuronium-induced withdrawal movement. 120 patients were randomly assigned to one of three groups to receive either saline, lidocaine 20mg, or palonosetron 0.075mg with a tourniquet applied two minutes before thiopental sodium (5mg.kg -1 ) was given intravenously. After loss of consciousness, rocuronium (0.6mg.kg -1 ) was injected and the withdrawal movement was estimated by 4-point scale in a double-blind manner. The overall incidence of rocuronium withdrawal movement was 50% with lidocaine (p=0.038), 38% with palonosetron (p=0.006) compared with 75% for saline. The incidence of no pain to mild pain was significantly lower in the lidocaine and palonosetron groups (85% and 92% respectively) than in the saline group (58%). However, there was no significant difference in withdrawal movement between the lidocaine and palonosetron groups. There was no severe movement with palonosetron. Pretreatment of palonosetron with venous occlusion may attenuate rocuronium-induced withdrawal movement as effective as the use of lidocaine. It suggested that peripheral action of palonosetron was effective to reduce rocuronium-induced withdrawal movement. Copyright © 2016. Publicado por Elsevier Editora Ltda.

  6. [Treatment of gamma-hydroxybutyrate withdrawal].

    Science.gov (United States)

    Strand, Niels August Willer; Petersen, Tonny Studsgaard; Nielsen, Lars Martin; Boegevig, Soren

    2017-12-11

    Gamma-hydroxybutyrate (GHB) is a drug of abuse, for which physical addiction develops quickly. GHB withdrawal can develop into a life-threatening condition and has previously been treated mainly with benzodiazepines. These have not always proven effective, leading to long hospitalizations in intensive care units. Based on successful Dutch treatment results for using GHB to treat GHB withdrawal symptoms, we propose to implement a similar method in Denmark. The method requires an interdisciplinary effort for which The Danish Poison Information Centre should be consulted for expertise.

  7. 21 CFR 171.7 - Withdrawal of petition without prejudice.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 3 2010-04-01 2009-04-01 true Withdrawal of petition without prejudice. 171.7... Withdrawal of petition without prejudice. (a) In some cases the Commissioner will notify the petitioner that... clarification or the obtaining of additional data. This withdrawal will be without prejudice to a future filing...

  8. 21 CFR 571.7 - Withdrawal of petition without prejudice.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Withdrawal of petition without prejudice. 571.7... Withdrawal of petition without prejudice. (a) In some cases the Commissioner will notify the petitioner that... clarification or the obtaining of additional data. This withdrawal will be without prejudice to a future filing...

  9. Narp regulates long-term aversive effects of morphine withdrawal

    Science.gov (United States)

    Reti, Irving M.; Crombag, Hans S.; Takamiya, Kogo; Sutton, Jeffrey M.; Guo, Ning; Dinenna, Megan L.; Huganir, Richard L.; Holland, Peter C.; Baraban, Jay M.

    2008-01-01

    Although long-lasting effects of drug withdrawal are thought to play a key role in motivating continued drug use, the mechanisms mediating this type of drug-induced plasticity are unclear. As Narp is an immediate early gene product that is secreted at synaptic sites and binds to AMPA receptors, it has been implicated in mediating enduring forms of synaptic plasticity. In previous studies, we found that Narp is selectively induced by morphine withdrawal in the extended amygdala, a group of limbic nuclei that mediate aversive behavioral responses. Accordingly, in this study, we evaluated whether long-term aversive effects of morphine withdrawal are altered in Narp KO mice. We found that acute physical signs of morphine withdrawal are unaffected by Narp deletion. However, Narp KO mice acquire and sustain more aversive responses to the environment conditioned with morphine withdrawal than WT controls. Paradoxically, Narp KO mice undergo accelerated extinction of this heightened aversive response. Taken together, these studies suggest that Narp modulates both acquisition and extinction of aversive responses to morphine withdrawal and, therefore, may regulate plasticity processes underlying drug addiction. PMID:18729628

  10. A case of rhabdomyolysis associated with severe opioid withdrawal.

    Science.gov (United States)

    Gangahar, Deepali

    2015-08-01

    While the risk of opioid overdose is widely accepted, the dangers of opioid withdrawal are far less clearly defined. The purpose of this publication is to provide evidence against the erroneous clinical dictum that opioid withdrawal is never life-threatening. This case report (N = 1) illustrates an unfortunate, common scenario of a man abusing prescription opioids and heroin. His attempt at self-detoxification with buprenorphine-naloxone resulted in life-threatening opioid withdrawal. A detailed account of each day of his withdrawal period was documented by patient and family report and review of all medical records. The patient was contacted three months after hospitalization to verify information and determine progress in treatment and abstinence from drugs and alcohol. A review of the literature was completed on severe cases of precipitated and spontaneous opioid withdrawal followed by a discussion of the significance as it relates to this case. Given the widespread use of prescription opioids and opioid maintenance treatment, physicians should be aware of the complications of acute opioid withdrawal and should be equipped to treat these complications. © American Academy of Addiction Psychiatry.

  11. Low efficacy of non-opioid drugs in opioid withdrawal symptoms.

    Science.gov (United States)

    Hermann, Derik; Klages, Eckard; Welzel, Helga; Mann, Karl; Croissant, Bernhard

    2005-06-01

    Opioid withdrawal, stress or cues associated with opioid consumption can induce opioid craving. If opioids are not available, opioid-dependent patients usually search for alternative drugs. Because several non-opioid drugs stimulate the endogenous opioidergic system, this concept may explain their frequent use by opioid-dependent patients. We hypothesized that non-opioid drugs alleviate opioid withdrawal symptoms and are therefore consumed by opioid addicts. We asked 89 opioid-dependent patients participating in an out-patient opioid maintenance program to estimate the potential of several non-opioid drugs in being able to alleviate opioid withdrawal. We applied a five-point Lickert scale (1 = very good reduction of opioid withdrawal; 5 = no reduction of opioid withdrawal). Patients could also indicate a worsening of opioid withdrawal. Values (mean +/- SD) were: for benzodiazepines, 3.2 +/- 1.1; tricyclic antidepressants, 3.6 +/- 1.1; cannabis, 3.6 +/- 1.0; alcohol, 4.1 +/- 1.1; cocaine, 4.2 +/- 1.1; amphetamine, 4.4 +/- 0.9; nicotine, 4.7 +/- 0.7; and caffeine, 4.9 +/- 0.5. A worsening of opioid withdrawal was reported by 62% of the patients for cocaine, 62% for amphetamine, 50% for caffeine, 37.5% for cannabis, 27% for nicotine, 26% for alcohol, 8% for tricyclic antidepressants and 3% for benzodiazepines. Our study shows a low efficacy of non-opioid drugs in alleviating opioid withdrawal symptoms. The data basis of this study was good and the sample was suitable to be asked for estimations of drug-drug interactions. Of the patients, 26 - 62% even reported a worsening of opioid withdrawal for cannabis, alcohol, cocaine and amphetamine. Only benzodiazepines and tricyclic antidepressants were reported to have a moderate positive effect on opioid withdrawal.

  12. 49 CFR 450.16 - Withdrawal of delegation.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 6 2010-10-01 2010-10-01 false Withdrawal of delegation. 450.16 Section 450.16... SECURITY SAFETY APPROVAL OF CARGO CONTAINERS GENERAL Procedure for Delegation to Approval Authorities § 450.16 Withdrawal of delegation. (a) The Chief, Office of Operating and Environmental Standards (CG-522...

  13. 20 CFR 410.690 - Withdrawal of charges.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Withdrawal of charges. 410.690 Section 410.690 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL COAL MINE HEALTH AND SAFETY ACT OF 1969... Review, Finality of Decisions, and Representation of Parties § 410.690 Withdrawal of charges. If an...

  14. CONSUMER'S RIGHT TO WITHDRAW

    Directory of Open Access Journals (Sweden)

    ANCA NICOLETA GHEORGHE

    2013-05-01

    Full Text Available The right of withdrawal (of a contract belongs to the consumer, and is an essential means for the improvement of regulations that protect the consumer.. Right of withdrawal is not a recent creation and is not even specific to the consumer field. He was previously recognized in civil and commercial law (without special regulation. The right to withdraw may even have as ground the parties will. Thus, based on the contractual freedom, the parties may agree that one of them has the right to terminate the contract unilaterally The possibility of unilateral denunciation of the contract, gives the consumer, added protection by being able to reflect the decision and to check how the trader fulfil its obligations. In this context, through its effects, the right of denunciation, forces the professional parties to conduct themselves as fair as possible to the consumer and to execute the contract properly. In the study of the consumer protection, the time of conclusion is essential because in this stage is manifested, the inequality between the consumer and professional. Thus, the lack of information, the major of products and activities, commercial practices, influence the formation of consumer will, preventing the expression of a freely and knowingly consent.

  15. Neural mechanisms underlying morphine withdrawal in addicted patients: a review

    Directory of Open Access Journals (Sweden)

    Nima Babhadiashar

    2015-06-01

    Full Text Available Morphine is one of the most potent alkaloid in opium, which has substantial medical uses and needs and it is the first active principle purified from herbal source. Morphine has commonly been used for relief of moderate to severe pain as it acts directly on the central nervous system; nonetheless, its chronic abuse increases tolerance and physical dependence, which is commonly known as opiate addiction. Morphine withdrawal syndrome is physiological and behavioral symptoms that stem from prolonged exposure to morphine. A majority of brain regions are hypofunctional over prolonged abstinence and acute morphine withdrawal. Furthermore, several neural mechanisms are likely to contribute to morphine withdrawal. The present review summarizes the literature pertaining to neural mechanisms underlying morphine withdrawal. Despite the fact that morphine withdrawal is a complex process, it is suggested that neural mechanisms play key roles in morphine withdrawal.

  16. 75 FR 27362 - Notice of Temporary Order Restricting Dogs From Public Lands in the Kasha-Katuwe Tent Rocks...

    Science.gov (United States)

    2010-05-14

    ... Temporary Order Restricting Dogs From Public Lands in the Kasha-Katuwe Tent Rocks National Monument in... dogs from public lands within the 5,610- acre Kasha-Katuwe Tent Rocks National Monument. This order... persons with dogs is prohibited on public land in New Mexico Prime Meridian, T. 16 N., R. 5 E., and T. 17...

  17. Establishing a Water Resources Resilience Baseline for Mexico City

    Science.gov (United States)

    Behzadi, F.; Ray, P. A.

    2017-12-01

    There is a growing concern for the vulnerability of the Mexico City water system to shocks, and the capacity of the system to accommodate climate and demographic change. This study presents a coarse-resolution, lumped model of the water system of Mexico City as a whole, designed to identify system-wide imbalances, and opportunities for large-scale improvements in city-wide resilience through investments in water imports, exports, and storage. In order to investigate the impact of climate change in Mexico City, the annual and monthly trends of precipitation and temperature at 46 stations near or inside the Mexico City were analyzed. The statistical significance of the trends in rainfall and temperature, both over the entire period of record, and the more recent "climate-change-impacted period" (1970-2015), were determined using the non-parametric Mann-Kendall test. Results show a statistically significant increasing trend in the annual mean precipitation, mean temperature, and annual maximum daily temperature. However, minimum daily temperature does not appear to be increasing, and might be decreasing. Water management in Mexico City faces particular challenges, where the winter dry season is warming more quickly than the wet summer season. A stress test of Mexico City water system is conducted to identify vulnerabilities to changes in exogenous factors (esp., climate, demographics, land use). Following on the stress test, the relative merits of adaptation options that might improve the system's resilience and sustainability will be assessed.

  18. 77 FR 32666 - Notice of Public Meeting, Pecos District Resource Advisory Council Meeting, New Mexico

    Science.gov (United States)

    2012-06-01

    ..., 575-627-0242. Persons who use a telecommunications device for the deaf (TDD) may call the Federal... of planning and management issues associated with public land management in New Mexico. Planned...

  19. Opioid antagonists with minimal sedation for opioid withdrawal.

    Science.gov (United States)

    Gowing, Linda; Ali, Robert; White, Jason M

    2017-05-29

    Managed withdrawal is a necessary step prior to drug-free treatment or as the endpoint of long-term substitution treatment. To assess the effects of opioid antagonists plus minimal sedation for opioid withdrawal. Comparators were placebo as well as more established approaches to detoxification, such as tapered doses of methadone, adrenergic agonists, buprenorphine and symptomatic medications. We updated our searches of the following databases to December 2016: CENTRAL, MEDLINE, Embase, PsycINFO and Web of Science. We also searched two trials registers and checked the reference lists of included studies for further references to relevant studies. We included randomised and quasi-randomised controlled clinical trials along with prospective controlled cohort studies comparing opioid antagonists plus minimal sedation versus other approaches or different opioid antagonist regimens for withdrawal in opioid-dependent participants. We used standard methodological procedures expected by Cochrane. Ten studies (6 randomised controlled trials and 4 prospective cohort studies, involving 955 participants) met the inclusion criteria for the review. We considered 7 of the 10 studies to be at high risk of bias in at least one of the domains we assessed.Nine studies compared an opioid antagonist-adrenergic agonist combination versus a treatment regimen based primarily on an alpha 2 -adrenergic agonist (clonidine or lofexidine). Other comparisons (placebo, tapered doses of methadone, buprenorphine) made by included studies were too diverse for any meaningful analysis. This review therefore focuses on the nine studies comparing an opioid antagonist (naltrexone or naloxone) plus clonidine or lofexidine versus treatment primarily based on clonidine or lofexidine.Five studies took place in an inpatient setting, two studies were in outpatients with day care, two used day care only for the first day of opioid antagonist administration, and one study described the setting as outpatient

  20. 75 FR 55349 - Notice of Realty Action: Modified Competitive Sealed Bid Sale of Public Lands in Rio Arriba...

    Science.gov (United States)

    2010-09-10

    ... land totaling approximately 160 acres in Lindrith, New Mexico. The sale parcel will be subject to the... Federal purpose and would be sold for not less than Fair Market Value (FMV), currently appraised to be $96... Office, 1235 La Plata Highway, Suite A, Farmington, New Mexico 87401. FOR FURTHER INFORMATION CONTACT...

  1. Gradual withdrawal of remifentanil infusion may prevent opioid-induced hyperalgesia.

    Science.gov (United States)

    Comelon, M; Raeder, J; Stubhaug, A; Nielsen, C S; Draegni, T; Lenz, H

    2016-04-01

    The aim of this study was to examine if gradual withdrawal of remifentanil infusion prevented opioid-induced hyperalgesia (OIH) as opposed to abrupt withdrawal. OIH duration was also evaluated. Nineteen volunteers were enrolled in this randomized, double-blinded, placebo-controlled, crossover study. All went through three sessions: abrupt or gradual withdrawal of remifentanil infusion and placebo. Remifentanil was administered at 2.5 ng ml(-1) for 30 min before abrupt withdrawal or gradual withdrawal by 0.6 ng ml(-1) every five min. Pain was assessed at baseline, during infusion, 45-50 min and 105-110 min after end of infusions using the heat pain test (HPT) and the cold pressor test (CPT). The HPT 45 min after infusion indicated OIH development in the abrupt withdrawal session with higher pain scores compared with the gradual withdrawal and placebo sessions (both Pwithdrawal compared with placebo (P=0.93). In the CPT 50 min after end of infusion there was OIH in both remifentanil sessions compared with placebo (gradual P=0.01, abrupt Pwithdrawal of remifentanil infusion in the HPT. After abrupt withdrawal OIH was present in the HPT. In the CPT there was OIH after both gradual and abrupt withdrawal of infusion. The duration of OIH was less than 105 min for both pain modalities. NCT 01702389. EudraCT number 2011-002734-39. © The Author 2016. Published by Oxford University Press on behalf of the British Journal of Anaesthesia. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  2. More troubles in Gulf of Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Winter, K.

    1980-08-01

    According to K. Winter of the University of Texas Marine Science Institute, tanker operators are conducting illegal cleaning operations in the Gulf of Mexico because they believe residual Ixtoc I oil will camouflage their actions. Oil has been spotted coming ashore recently, most of which has not been from the Ixtoc I well. The National Oceanic and Atmospheric Administration/U.S. Bureau of Land Management dispute over responsibility for studies of the effects of the Ixtoc I spill is briefly discussed.

  3. Two-day thionamide withdrawal prior to radioiodine uptake sufficiently increases uptake and does not exacerbate hyperthyroidism compared to 7-day withdrawal in Graves' disease

    International Nuclear Information System (INIS)

    Kubota, Sumihisa; Ohye, Hidemi; Yano, Genichiro; Nishihara, Eijun; Kudo, Takumi; Ito, Mitsuru; Fukata, Shuji; Amino, Nobuyuki; Kuma, Kanji; Miyauchi, Akira

    2006-01-01

    The appropriate period of antithyroid drug (ATD) discontinuation before radioiodine therapy is the most critical problem in Graves' disease patients under going treatment with ATD. To determine the optimal period that does not alter the outcome of radioiodine therapy or exacerbate hyperthyroidism, we compared serum FT4 levels at radioiodine uptake (RAIU) and therapy outcomes between a 2-day withdrawal group and 7-day withdrawal group. We prospectively recruited 43 patients for the 2-day withdrawal protocol and retrospectively reviewed 49 patients treated with radioiodine following the protocol of 7-day withdrawal. There was no significant difference in RAIU between the 2 groups. The mean serum FT4 level measured on the first day of 24-h RAIU of the 7-day group was significantly higher than that in the 2-day group. There were no significant differences in the outcomes at each point (6 months, 1 year, and 2 years after therapy) between the 2 groups. Our results indicated that withdrawal of ATD for 2 days is superior to 7 days in that 2 days discontinuation did not exacerbate hyperthyroidism. In order to prevent serum thyroid hormone increase after ATD withdrawal and radioiodine therapy, a 2-day ATD withdrawal period before radioiodine therapy may be useful for high-risk patients such as the elderly and patients with cardiac complications. We believe that the 2-day ATD withdrawal method may be useful for patients undergoing treatment with ATD who are to undergo radioiodine therapy. (author)

  4. Acute coronary ischemia during alcohol withdrawal: a case report

    Directory of Open Access Journals (Sweden)

    Sriram Ganeshalingam

    2011-08-01

    Full Text Available Abstract Introduction The potential of alcohol withdrawal to cause acute coronary events is an area that needs the urgent attention of clinicians and researchers. Case presentation We report the case of a 52-year-old heavy-alcohol-using Sri Lankan man who developed electocardiogram changes suggestive of an acute coronary event during alcohol withdrawal. Despite the patient being asymptomatic, subsequent echocardiogram showed evidence of ischemic myocardial dysfunction. We review the literature on precipitation of myocardial ischemia during alcohol withdrawal and propose possible mechanisms. Conclusions Alcohol withdrawal is a commonly observed phenomenon in hospitals. However, the number of cases reported in the literature of acute coronary events occurring during withdrawal is few. Many cases of acute ischemia or sudden cardiac deaths may be attributed to other well known complications of delirium tremens. This is an area needing the urgent attention of clinicians and epidemiologists.

  5. Role of forest conservation in lessening land degradation in a temperate region: the Monarch Butterfly Biosphere Reserve, Mexico.

    Science.gov (United States)

    Manzo-Delgado, Lilia; López-García, José; Alcántara-Ayala, Irasema

    2014-06-01

    With international concern about the rates of deforestation worldwide, particular attention has been paid to Latin America. Forest conservation programmes in Mexico include Payment for Environmental Services (PES), a scheme that has been successfully introduced in the Monarch Butterfly Biosphere Reserve. To seek further evidence of the role of PES in lessening land degradation processes in a temperate region, the conservation state of the Cerro Prieto ejido within the Reserve was assessed by an analysis of changes in vegetation cover and land-use between 1971 and 2013. There were no changes in the total forest surface area, but the relative proportions of the different classes of cover density had changed. In 1971, closed and semi-closed forest occupied 247.81 ha and 5.38 ha, 82.33% and 1.79% of the total area of the ejido, respectively. By 2013, closed forest had decreased to 230.38 ha (76.54% of the ejido), and semi-closed cover was 17.23 ha (5.72% of the ejido), suggesting that some semi-closed forest had achieved closed status. The final balance between forest losses and recovery was: 29.63 ha were lost, whereas 13.72 ha were recovered. Losses were mainly linked to a sanitation harvest programme to control the bark beetle Scolytus mundus. Ecotourism associated with forest conservation in the Cerro Prieto ejido has been considered by inhabitants as a focal alternative for economic development. Consequently, it is essential to develop a well-planned and solidly structured approach based on social cohesion to foster a community-led sustainable development at local level. Copyright © 2013 Elsevier Ltd. All rights reserved.

  6. TRACY transient experiment databook. 2) ramp withdrawal experiment

    International Nuclear Information System (INIS)

    Nakajima, Ken; Yamane, Yuichi; Ogawa, Kazuhiko; Aizawa, Eiju; Yanagisawa, Hiroshi; Miyoshi, Yoshinori

    2002-03-01

    This is a databook of TRACY ''ramp withdrawal'' experiments. TRACY is a reactor to perform supercritical experiments using low-enriched uranyl nitrate aqueous solution. The excess reactivity of TRACY is 3$ at maximum, and it is inserted by feeding the solution to a core tank or by withdrawing a control rod, which is called as the transient rod, from the core. In the ramp withdrawal experiment, the supercritical experiment is initiated by withdrawing the transient rod from the core in a constant speed using a motor drive system. The data in the present databook consist of datasheets and graphs. Experimental conditions and typical values of measured parameters are tabulated in the datasheet. In the graph, power and temperature profiles are plotted. Those data are useful for the investigation of criticality accidents with fissile solutions, and for validation of criticality accident analysis codes. (author)

  7. Buying land for conservation purposes in Sonora, Mexico

    Science.gov (United States)

    S. Lucia Perez-Weil; Juan Carlos G. Bravo

    2013-01-01

    The Northern Jaguar Reserve is 50,000 acres and one of the largest privately owned wildlife preserves in Sonora. Buying land in remote parts of Sonora takes special knowledge as ownership rules may not be clear and boundaries may not be defined in the records. There are complex legal procedures to guarantee ownership in which letters of intent play a crucial role, and...

  8. Cannabis Withdrawal in Adults With Attention-Deficit/Hyperactivity Disorder.

    Science.gov (United States)

    Chauchard, Emeline; Hartwell, Karen J; McRae-Clark, Aimee L; Sherman, Brian J; Gorelick, David A

    2018-02-22

    Cannabis withdrawal has not been studied in adults with attention-deficit/hyperactivity disorder (ADHD) who have high rates of cannabis use. We aimed to describe cannabis withdrawal, motivations to quit, and strategies to quit cannabis use in cannabis-dependent adults with ADHD. Twenty-three adults with ADHD enrolled in a controlled clinical trial of pharmacotherapy (atomoxetine) for cannabis dependence (DSM-IV criteria) completed the Marijuana Quit Questionnaire (MJQQ) to provide information on their "most serious" quit attempt made without formal treatment. The study was conducted between November 2005 and June 2008. Participants were predominantly male (82.6%, n = 19), with a mean (SD) age of 27.4 (8.5) years (range, 18-53) at the start of their index quit attempt. The most common motive for quitting cannabis was "to save money" (87%, n = 20); the most common strategy to maintain abstinence was "stopped associating with people who smoke marijuana" (43%, n = 10). Almost all (96%, n = 22) subjects reported ≥ 1 cannabis withdrawal symptom; 7 (30%) met DSM-5 diagnostic criteria for cannabis withdrawal syndrome. Participants with comorbid ADHD and cannabis dependence reported withdrawal symptoms similar to other samples of non-treatment-seeking cannabis-dependent adults with no psychiatric comorbidity. These findings suggest that ADHD does not influence cannabis withdrawal in the way that it does tobacco (nicotine) withdrawal. Data used in this secondary analysis came from ClinicalTrials.gov identifier: NCT00360269. © Copyright 2018 Physicians Postgraduate Press, Inc.

  9. 40 CFR 97.86 - Withdrawal from NOX Budget Trading Program.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Withdrawal from NOX Budget Trading... PROGRAMS (CONTINUED) FEDERAL NOX BUDGET TRADING PROGRAM AND CAIR NOX AND SO2 TRADING PROGRAMS Individual Unit Opt-ins. § 97.86 Withdrawal from NOX Budget Trading Program. (a) Requesting withdrawal. To...

  10. 42 CFR 8.6 - Withdrawal of approval of accreditation bodies.

    Science.gov (United States)

    2010-10-01

    ... PROVISIONS CERTIFICATION OF OPIOID TREATMENT PROGRAMS Accreditation § 8.6 Withdrawal of approval of... 42 Public Health 1 2010-10-01 2010-10-01 false Withdrawal of approval of accreditation bodies. 8.6... to establish that the problems that were grounds for withdrawal of approval have been resolved. (2...

  11. Neurobiology of opioid withdrawal: Role of the endothelin system.

    Science.gov (United States)

    Bhalla, Shaifali; Andurkar, Shridhar V; Gulati, Anil

    2016-08-15

    Morphine and oxycodone are potent opioid analgesics most commonly used for the management of moderate to severe acute and chronic pain. Their clinical utility is limited by undesired side effects like analgesic tolerance, dependence, and withdrawal. We have previously demonstrated that endothelin-A (ETA) receptor antagonists potentiate opioid analgesia and eliminate analgesic tolerance. Mechanistically, G proteins and regulatory proteins such as β-arrestins have shown to play an important role in mediating opioid tolerance, dependence, and withdrawal. Recently, the involvement of central ET mechanisms in opioid withdrawal was investigated. ETA receptor antagonist was shown to block majority of the signs and symptoms associated with opioid withdrawal. This review focuses on ET as one of the potential novel strategies to manage the challenge of opioid withdrawal. An overview of additional players in this process (G proteins and β-arrestin2), and the possible therapeutic implications of these findings are presented. Copyright © 2016 Elsevier Inc. All rights reserved.

  12. Economic and financial viability of small-scale dairy systems in central Mexico: economic scenario 2010-2018.

    Science.gov (United States)

    Posadas-Domínguez, R R; Callejas-Juárez, N; Arriaga-Jordán, C M; Martínez-Castañeda, F E

    2016-12-01

    A simulation Monte Carlo model was used to assess the economic and financial viability of 130 small-scale dairy farms in central Mexico, through a Representative Small-Scale Dairy Farm. Net yields were calculated for a 9-year planning horizon by means of simulated values for the distribution of input and product prices taking 2010 as base year and considering four scenarios which were compared against the scenario of actual production. The other scenarios were (1) total hiring in of needed labour; (2) external purchase of 100 % of inputs and (3) withdrawal of subsidies to production. A stochastic modelling approach was followed to determine the scenario with the highest economic and financial viability. Results show a viable economic and financial situation for the real production scenario, as well as the scenarios for total hiring of labour and of withdrawal of subsidies, but the scenario when 100 % of feed inputs for the herd are bought-in was not viable.

  13. Space-based monitoring of land-use/land-cover in the Upper Rio Grande Basin: An opportunity for understanding urbanization trends in a water-scarce transboundary river basin.

    Science.gov (United States)

    Mubako, S. T.; Hargrove, W. L.; Heyman, J. M.; Reyes, C. S.

    2016-12-01

    Urbanization is an area of growing interest in assessing the impact of human activities on water resources in arid regions. Remote sensing techniques provide an opportunity to analyze land cover change over time, and are useful in monitoring areas undergoing rapid urban growth. This case study for the water-scarce Upper Rio Grande River Basin uses a supervised classification algorithm to quantify the rate and evaluate the pattern of urban sprawl. A focus is made on the fast growing El-Paso-Juarez metropolitan area on the US-Mexico border and the City of Las Cruces in New Mexico, areas where environmental challenges and loss of agricultural and native land to urban development are major concerns. Preliminary results show that the land cover is dominantly native with some significant agriculture along the Rio Grande River valley. Urban development across the whole study area expanded from just under 3 percent in 1990, to more than 11 percent in 2015. The urban expansion is occurring mainly around the major urban areas of El Paso, Ciudad Juarez, and Las Cruces, although there is visible growth of smaller urban settlements scattered along the Rio Grande River valley during the same analysis period. The proportion of native land cover fluctuates slightly depending on how much land is under crops each analysis year, but there is a decreasing agricultural land cover trend suggesting that land from this sector is being lost to urban development. This analysis can be useful in planning to protect the environment, preparing for growth in infrastructure such as schools, increased traffic demands, and monitoring availability of resources such as groundwater as the urban population grows.

  14. Tobacco withdrawal symptoms mediate motivation to reinstate smoking during abstinence.

    Science.gov (United States)

    Aguirre, Claudia G; Madrid, Jillian; Leventhal, Adam M

    2015-08-01

    Withdrawal-based theories of addiction hypothesize that motivation to reinstate drug use following acute abstinence is mediated by withdrawal symptoms. Experimental tests of this hypothesis in the tobacco literature are scant and may be subject to methodological limitations. This study utilized a robust within-subject laboratory experimental design to investigate the extent to which composite tobacco withdrawal symptomatology level and 3 unique withdrawal components (i.e., low positive affect, negative affect, and urge to smoke) mediated the effect of smoking abstinence on motivation to reinstate smoking. Smokers (≥10 cigarettes per day; N = 286) attended 2 counterbalanced sessions at which abstinence duration was differentially manipulated (1 hr vs. 17 hr). At both sessions, participants reported current withdrawal symptoms and subsequently completed a task in which they were monetarily rewarded proportional to the length of time they delayed initiating smoking, with shorter latency reflecting stronger motivation to reinstate smoking. Abstinence reduced latency to smoking initiation and positive affect and increased composite withdrawal symptom level, urge, and negative affect. Abstinence-induced reductions in latency to initiating smoking were mediated by each withdrawal component, with stronger effects operating through urge. Combined analyses suggested that urge, negative affect, and low positive affect operate through empirically unique mediational pathways. Secondary analyses suggested similar effects on smoking quantity, few differences among specific urge and affect subtypes, and that dependence amplifies some abstinence effects. This study provides the first experimental evidence that within-person variation in abstinence impacts motivation to reinstate drug use through withdrawal. Urge, negative affect, and low positive affect may reflect unique withdrawal-mediated mechanisms underlying tobacco addiction. (c) 2015 APA, all rights reserved).

  15. Social Withdrawal, Friendship, and Depressed Mood in Adolescents

    NARCIS (Netherlands)

    Aleva, A.E.|info:eu-repo/dai/nl/141299789; van Beek, Y.|info:eu-repo/dai/nl/107292300

    2017-01-01

    Social withdrawal in children may develop into a depressed mood in early adolescence , through experiences of problematic peer relationships, while friendship may function as a buffer (Rubin, Coplan, & Bowker, 2009). Our study examines the predictive relation between social withdrawal and depressive

  16. Biomass production in the Lower Mississippi River Basin: Mitigating associated nutrient and sediment discharge to the Gulf of Mexico.

    Science.gov (United States)

    Ha, Miae; Zhang, Zhonglong; Wu, May

    2018-04-24

    A watershed model was developed using the Soil and Water Assessment Tool (SWAT) that simulates nitrogen, phosphorus, and sediment loadings in the Lower Mississippi River Basin (LMRB). The LMRB SWAT model was calibrated and validated using 21 years of observed flow, sediment, and water-quality data. The baseline model results indicate that agricultural lands within the Lower Mississippi River Basin (LMRB) are the dominant sources of nitrogen and phosphorus discharging into the Gulf of Mexico. The model was further used to evaluate the impact of biomass production, in the presence of riparian buffers in the LMRB, on suspended-sediment and nutrient loading discharge from the Mississippi River into the Gulf of Mexico. The interplay among land use, riparian buffers, crop type, land slope, water quality, and hydrology were anlyzed at various scales. Implementing a riparian buffer in the dominant agricultural region within the LMRB could reduce suspended sediment, nitrogen, and phosphorus loadings at the regional scale by up to 65%, 38%, and 39%, respectively. Implementation of this land management practice can reduce the suspended-sediment content and improve the water quality of the discharge from the LMRB into the Gulf of Mexico and support the potential production of bioenergy and bio-products within the Mississippi River Basin. Copyright © 2017 Elsevier B.V. All rights reserved.

  17. Prolonged social withdrawal disorder: a hikikomori case in Spain.

    Science.gov (United States)

    Ovejero, Santiago; Caro-Cañizares, Irene; de León-Martínez, Victoria; Baca-Garcia, Enrique

    2014-09-01

    The Japanese term hikikomori means literally 'to be confined'. Social withdrawal can be present in severe psychiatric disorders; however, in Japan, hikikomori is a defined nosologic entity. There have been only a few reported cases in occidental culture. We present a case report of a Spanish man with prolonged social withdrawal lasting for 4 years. This is a case of prolonged social withdrawal not bound to culture, as well as the second case of hikikomori reported in Spain. We propose prolonged social withdrawal disorder as a disorder not linked to culture, in contrast to hikikomori. Further documentation of this disorder is still needed to encompass all cases reported in Japan and around the world. © The Author(s) 2013.

  18. Navajo-Hopi Land Commission Renewable Energy Development Project (NREP)

    Energy Technology Data Exchange (ETDEWEB)

    Thomas Benally, Deputy Director,

    2012-05-15

    The Navajo Hopi Land Commission Office (NHLCO), a Navajo Nation executive branch agency has conducted activities to determine capacity-building, institution-building, outreach and management activities to initiate the development of large-scale renewable energy - 100 megawatt (MW) or larger - generating projects on land in Northwestern New Mexico in the first year of a multi-year program. The Navajo Hopi Land Commission Renewable Energy Development Project (NREP) is a one year program that will develop and market a strategic business plan; form multi-agency and public-private project partnerships; compile site-specific solar, wind and infrastructure data; and develop and use project communication and marketing tools to support outreach efforts targeting the public, vendors, investors and government audiences.

  19. Alcohol withdrawal delirium manifested by manic symptoms in an elderly patient.

    Science.gov (United States)

    Chan, Hung-Yu; Lee, Kuan-I

    2015-03-01

    Alcohol withdrawal syndrome is a commonly seen problem in psychiatric practice. Alcohol withdrawal delirium is associated with significant morbidity and mortality. Withdrawal symptoms usually include tremulousness, psychotic and perceptual symptoms, seizures, and consciousness disturbance. Herein, we report a case involving a 63-year-old man who had alcohol withdrawal delirium that was manifested mainly by manic symptoms. © 2014 The Authors. Psychogeriatrics © 2014 Japanese Psychogeriatric Society.

  20. Development of a 30 m Spatial Resolution Land Cover of Canada: Contribution to the Harmonized North America Land Cover Dataset

    Science.gov (United States)

    Pouliot, D.; Latifovic, R.; Olthof, I.

    2017-12-01

    Land cover is needed for a large range of environmental applications regarding climate impacts and adaption, emergency response, wildlife habitat, air quality, water yield, etc. In Canada a 2008 user survey revealed that the most practical scale for provision of land cover data is 30 m, nationwide, with an update frequency of five years (Ball, 2008). In response to this need the Canada Centre for Remote Sensing has generated a 30 m land cover of Canada for the base year 2010 as part of a planned series of maps at the recommended five year update frequency. This land cover is the Canadian contribution to the North American Land Change Monitoring System initiative, which seeks to provide harmonized land cover across Canada, the United States, and Mexico. The methodology developed in this research utilized a combination of unsupervised and machine learning techniques to map land cover, blend results between mapping units, locally optimize results, and process some thematic attributes with specific features sets. Accuracy assessment with available field data shows it was on average 75% for the five study areas assessed. In this presentation an overview of the unique processing aspects, example results, and initial accuracy assessment will be discussed.

  1. Large-scale Vertical Motions, Intensity Change and Precipitation Associated with Land falling Hurricane Katrina over the Gulf of Mexico

    Science.gov (United States)

    Reddy, S. R.; Kwembe, T.; Zhang, Z.

    2016-12-01

    We investigated the possible relationship between the large- scale heat fluxes and intensity change associated with the landfall of Hurricane Katrina. After reaching the category 5 intensity on August 28th , 2005 over the central Gulf of Mexico, Katrina weekend to category 3 before making landfall (August 29th , 2005) on the Louisiana coast with the maximum sustained winds of over 110 knots. We also examined the vertical motions associated with the intensity change of the hurricane. The data for Convective Available Potential Energy for water vapor (CAPE), sea level pressure and wind speed were obtained from the Atmospheric Soundings, and NOAA National Hurricane Center (NHC), respectively for the period August 24 to September 3, 2005. We also computed vertical motions using CAPE values. The study showed that the large-scale heat fluxes reached maximum (7960W/m2) with the central pressure 905mb. The Convective Available Potential Energy and the vertical motions peaked 3-5 days before landfall. The large atmospheric vertical motions associated with the land falling hurricane Katrina produced severe weather including thunderstorm, tornadoes, storm surge and floods Numerical model (WRF/ARW) with data assimilations have been used for this research to investigate the model's performances on hurricane tracks and intensities associated with the hurricane Katrina, which began to strengthen until reaching Category 5 on 28 August 2005. The model was run on a doubly nested domain centered over the central Gulf of Mexico, with grid spacing of 90 km and 30 km for 6 hr periods, from August 28th to August 30th. The model output was compared with the observations and is capable of simulating the surface features, intensity change and track associated with hurricane Katrina.

  2. Environmental assessment of the Environmental Restoration Project at Sandia National Laboratories/New Mexico

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-03-01

    Sandia National Laboratories/New Mexico (SNL/NM) is managed and operated for the U.S. Department of Energy (DOE) by Sandia Corporation, a subsidiary of the Lockheed Martin Company. SNL/NM is located on land controlled by DOE within the boundaries of Kirtland Air Force Base (KAFB) in Albuquerque, New Mexico. The major responsibilities of SNL/NM are the support of national security and energy projects. This report provides an environmental assessment of proposed remedial action activities at the solid waste management units at SNL/NM. A risk assessment of health hazards is also discussed.

  3. Social Withdrawal and Maladjustment in a Very Group-Oriented Society

    Science.gov (United States)

    Valdivia, Ibis Alvarez; Schneider, Barry H.; Chavez, Kenia Lorenzo; Chen, Xinyin

    2005-01-01

    Elementary-school children in Cuba and Canada participated in measures of loneliness, sociometric status, friendship, aggression, and social withdrawal. Withdrawal was associated with loneliness in the Cuban data from both cohorts, Grade 4 and Grade 6. In the Canadian data, withdrawal was only linked to loneliness in Grade 6. In contrast with…

  4. Determination of intensity functions for predicting subsidence from coal mining, potash mining, and groundwater withdrawal using the influence function technique

    Energy Technology Data Exchange (ETDEWEB)

    Triplett, T; Yurchak, D [Twin Cities Research Center, Bureau of Mines, US Dept. of the Interior, Minneapolis, MN (United States)

    1997-12-31

    This paper presents research, conducted by the Bureau of Mines, on modifying the influence function method to predict subsidence. According to theory, this technique must incorporate an intensity function to represent the relative significance of the causes of subsidence. This paper shows that the inclusion of a reasonable intensity function increases the accuracy of the technique, then presents the required functions for case studies of longwall coal mining subsidence in Illinois, USA, potash mining subsidence in new Mexico, USA, and subsidence produced by ground water withdrawal in California, USA. Finally, the paper discusses a method to predict the resultant strain from a simply measured site constant and ground curvatures calculated by the technique. (orig.)

  5. Determination of intensity functions for predicting subsidence from coal mining, potash mining, and groundwater withdrawal using the influence function technique

    Energy Technology Data Exchange (ETDEWEB)

    Triplett, T.; Yurchak, D. [Twin Cities Research Center, Bureau of Mines, US Dept. of the Interior, Minneapolis, MN (United States)

    1996-12-31

    This paper presents research, conducted by the Bureau of Mines, on modifying the influence function method to predict subsidence. According to theory, this technique must incorporate an intensity function to represent the relative significance of the causes of subsidence. This paper shows that the inclusion of a reasonable intensity function increases the accuracy of the technique, then presents the required functions for case studies of longwall coal mining subsidence in Illinois, USA, potash mining subsidence in new Mexico, USA, and subsidence produced by ground water withdrawal in California, USA. Finally, the paper discusses a method to predict the resultant strain from a simply measured site constant and ground curvatures calculated by the technique. (orig.)

  6. Demand-Withdraw Patterns in Marital Conflict in the Home

    OpenAIRE

    Papp, Lauren M.; Kouros, Chrystyna D.; Cummings, E. Mark

    2009-01-01

    The present study extended laboratory-based findings of demand-withdraw communication into marital conflict in the home and further explored its linkages with spousal depression. U.S. couples (N = 116) provided diary reports of marital conflict and rated depressive symptoms. Hierarchical linear modeling results indicated that husband demand-wife withdraw and wife demand-husband withdraw occurred in the home at equal frequency, and both were more likely to occur when discussing topics that con...

  7. Ethical Analysis of Withdrawing Total Artificial Heart Support.

    Science.gov (United States)

    DeMartino, Erin S; Wordingham, Sara E; Stulak, John M; Boilson, Barry A; Fuechtmann, Kayla R; Singh, Nausheen; Sulmasy, Daniel P; Pajaro, Octavio E; Mueller, Paul S

    2017-05-01

    To describe the characteristics of patients who undergo withdrawal of total artificial heart support and to explore the ethical aspects of withdrawing this life-sustaining treatment. We retrospectively reviewed the medical records of all adult recipients of a total artificial heart at Mayo Clinic from the program's inception in 2007 through June 30, 2015. Management of other life-sustaining therapies, approach to end-of-life decision making, engagement of ethics and palliative care consultation, and causes of death were analyzed. Of 47 total artificial heart recipients, 14 patients or their surrogates (30%) requested withdrawal of total artificial heart support. No request was denied by treatment teams. All 14 patients were supported with at least 1 other life-sustaining therapy. Only 1 patient was able to participate in decision making. It is widely held to be ethically permissible to withdraw a life-sustaining treatment when the treatment no longer meets the patient's health care-related goals (ie, the burdens outweigh the benefits). These data suggest that some patients, surrogates, physicians, and other care providers believe that this principle extends to the withdrawal of total artificial heart support. Copyright © 2017 Mayo Foundation for Medical Education and Research. Published by Elsevier Inc. All rights reserved.

  8. Alcohol Withdrawal Mimicking Organophosphate Poisoning

    Directory of Open Access Journals (Sweden)

    Nezihat Rana Disel

    2014-02-01

    Full Text Available Organophosphates, which can cause occupational poisoning due to inappropriate personal protective measures, are widely used insecticides in agricultural regions of southern Turkey. Therefore, the classical clinical findings of this cholinergic poisoning are myosis, excessive secretions, bradicardia and fasciculations are easy to be recognized by local medical stuff. Diseases and conditions related to alcoholism such as mental and social impairments, coma, toxicity, withdrawal, and delirium are frequent causes of emergency visits of chronic alcoholic patients. Here we present a case diagnosed and treated as organophosphate poisoning although it was an alcohol withdrawal in the beginning and became delirium tremens, due to similar symptoms.

  9. Induction of synaptic long-term potentiation after opioid withdrawal.

    Science.gov (United States)

    Drdla, Ruth; Gassner, Matthias; Gingl, Ewald; Sandkühler, Jürgen

    2009-07-10

    mu-Opioid receptor (MOR) agonists represent the gold standard for the treatment of severe pain but may paradoxically also enhance pain sensitivity, that is, lead to opioid-induced hyperalgesia (OIH). We show that abrupt withdrawal from MOR agonists induces long-term potentiation (LTP) at the first synapse in pain pathways. Induction of opioid withdrawal LTP requires postsynaptic activation of heterotrimeric guanine nucleotide-binding proteins and N-methyl-d-aspartate receptors and a rise of postsynaptic calcium concentrations. In contrast, the acute depression by opioids is induced presynaptically at these synapses. Withdrawal LTP can be prevented by tapered withdrawal and shares pharmacology and signal transduction pathways with OIH. These findings provide a previously unrecognized target to selectively combat pro-nociceptive effects of opioids without compromising opioid analgesia.

  10. Sedative-hypnotic drug withdrawal syndrome: recognition and treatment [digest].

    Science.gov (United States)

    Santos, Cynthia; Olmedo, Ruben E; Kim, Jeremy

    2017-03-22

    Sedative-hypnotic drugs include gamma-Aminobutyric acid (GABA)ergic agents such as benzodiazepines, barbiturates, gamma-Hydroxybutyric acid [GHB], gamma-Butyrolactone [GBL], baclofen, and ethanol. Chronic use of these substances can cause tolerance, and abrupt cessation or a reduction in the quantity of the drug can precipitate a life-threatening withdrawal syndrome. Benzodiazepines, phenobarbital, propofol, and other GABA agonists or analogues can effectively control symptoms of withdrawal from GABAergic agents. Managing withdrawal symptoms requires a patient-specific approach that takes into account the physiologic pathways of the particular drugs used as well as the patient's age and comorbidities. Adjunctive therapies include alpha agonists, beta blockers, anticonvulsants, and antipsychotics. Newer pharmacological therapies offer promise in managing withdrawal symptoms. [Points & Pearls is a digest of Emergency Medicine Practice].

  11. European Anarchism and its Early Influences in Mexico after the Paris Commune: 1871- 1881

    Directory of Open Access Journals (Sweden)

    Clara E. Lida

    2001-07-01

    Full Text Available This article examines the links between European anarchism and social and agrarian movements in Mexico  after the Paris Commune. During those years, while anarchists remained in clandestinity, they developed new revolutionary theories and practices. These included the organization in freely federated autonomous communes, and the right to the land and the product of labor. Occasionally, such reivindications intertwined with those of the agrarian communities in Mexico allowing for European anarchism and Mexican social and peasant groups to come in contact with each other.

  12. 75 FR 55347 - Notice of Realty Action: Competitive Sale of Public Land Near Aztec in San Juan County, NM

    Science.gov (United States)

    2010-09-10

    ... city limits in San Juan County, New Mexico. The sale will be subject to the applicable provisions of... sealed bids equal to or greater than the appraised fair market value of the land. Bidders who submit..., Suite A, Farmington, New Mexico 87401. Sealed bids must also be submitted to this address. Supplemental...

  13. Caffeine Withdrawal and Dependence: A Convenience Survey Among Addiction Professionals.

    Science.gov (United States)

    Budney, Alan J; Brown, Pamela C; Griffiths, Roland R; Hughes, John R; Juliano, Laura M

    2013-06-01

    Caffeine withdrawal was included in the research appendix of the DSM-IV to encourage additional research to assist with determining its status for the next version of the manual. Caffeine dependence was not included because of a lack of empirical research at the time of publication. This study assessed the beliefs of addiction professionals about the clinical importance of caffeine withdrawal and dependence. A 6-item survey was developed and delivered electronically to the members of six professional organizations that focus on addiction. Open-ended comments were also solicited. Five hundred members responded. The majority (95%) thought that cessation of caffeine could produce a withdrawal syndrome, and that caffeine withdrawal can have clinical importance (73%); however, only half (48%) thought that caffeine withdrawal should be included in the Diagnostic and Statistical Manual of Mental Disorders (DSM). A majority (58%) believed that some people develop caffeine dependence; however, only 44% indicated that it should be in the DSM. Comments suggested that trepidation about inclusion of caffeine diagnoses was due to the concerns about the field of psychiatry being criticized for including common disorders with a relatively low clinical severity. Others, however, expressed an urgent need to take caffeine-related problems more seriously. The majority of addiction professionals believe that caffeine withdrawal and dependence disorders exist and are clinically important; however, these professionals are divided in whether caffeine withdrawal and dependence should be included in DSM. Wider dissemination of the extant literature on caffeine withdrawal and additional research on caffeine dependence will be needed to provide additional guidance to policymakers and healthcare workers.

  14. Summary of urban stormwater quality in Albuquerque, New Mexico, 2003-12

    Science.gov (United States)

    Storms, Erik F.; Oelsner, Gretchen P.; Locke, Evan A.; Stevens, Michael R.; Romero, Orlando C.

    2015-01-01

    Urban stormwater in the Albuquerque metropolitan area was sampled by the U.S. Geological Survey in cooperation with the City of Albuquerque, the Albuquerque Metropolitan Arroyo Flood Control Authority, the New Mexico Department of Transportation, and the University of New Mexico. Stormwater was sampled from a network of monitoring stations from 2003 to 2012 by following regulatory requirements for the National Pollutant Discharge Elimination System stormwater permit. During this period, stormwater was sampled in the Albuquerque metropolitan area at outfalls from nine drainage basins with residential, industrial, commercial, agricultural, and undeveloped land uses. Stormwater samples were analyzed for selected physical and chemical characteristics, nutrients, major ions, metals, organic compounds, and bacteria.

  15. [Alcohol withdrawal syndrome dynamics during treatment with nooclerin (deanoli aceglumas)].

    Science.gov (United States)

    Agibalova, T V; Buzik, O Zh; Rychkova, O V; Smyshlyaev, A V; Rumbesht, V V

    2018-01-01

    To study the efficacy of nooclerin (deanoli aceglumas) in alcohol withdrawal syndrome assessed by clinical and biochemical characteristics. A multicenter, open, randomized, comparative study of nooclerin in the complex treatment of alcohol withdrawal syndrome included 90 patients. The patients were randomized into nooclerin group (n=55) and control group (n=35). Nooclerin reduced alcohol withdrawal symptoms more significantly throughout the whole study period. There were significant between-group differences on the Clinical Institute Withdrawal Assessment of Alcohol Scale (CIWA-Ar) and the Multidimensional Fatigue Inventory (МFI-20). However, patients exhibited no excessive activity. No adverse side-effects were observed.

  16. Opioid withdrawal syndrome: emerging concepts and novel therapeutic targets.

    Science.gov (United States)

    Rehni, Ashish K; Jaggi, Amteshwar S; Singh, Nirmal

    2013-02-01

    Opioid withdrawal syndrome is a debilitating manifestation of opioid dependence and responds poorly to the available clinical therapies. Studies from various in vivo and in vitro animal models of opioid withdrawal syndrome have led to understanding of its pathobiology which includes complex interrelated pathways leading to adenylyl cyclase superactivation based central excitation. Advancements in the elucidation of opioid withdrawal syndrome mechanisms have revealed a number of key targets that have been hypothesized to modulate clinical status. The present review discusses the neurobiology of opioid withdrawal syndrome and its therapeutic target recptors like calcitonin gene related peptide receptors (CGRP), N-methyl-D-aspartate (NMDA) receptors, gamma aminobutyric acid receptors (GABA), G-proteingated inwardly rectifying potassium (GIRK) channels and calcium channels. The present review further details the potential role of second messengers like calcium (Ca2+) / calmodulin-dependent protein kinase (CaMKII), nitric oxide synthase, cytokines, arachidonic acid metabolites, corticotropin releasing factor, fos and src kinases in causing opioid withdrawal syndrome. The exploitation of these targets may provide effective therapeutic agents for the management of opioid dependence-induced abstinence syndrome.

  17. Evaluation of Ashwagandha in alcohol withdrawal syndrome

    Directory of Open Access Journals (Sweden)

    Ruby B

    2012-10-01

    Full Text Available Objective: To evaluate the effect of Ashwagandha (ASW in attenuation of alcohol withdrawal in ethanol withdrawal mice model. Methods: Alcohol dependence was induced in mice by the oral, once-daily administration of 10% v/v ethanol (2 g/kg for one week. Once the animals were withdrawn from alcohol, the efficacy of ASW (200mg/kg and 500mg/kg in comparison with diazepam (1 mg/kg in the attenuation of withdrawal was studied using, pentylenetetrazole (PTZ kindling test for seizure threshold, forced swim test (FST for depression and locomotor activity (LCA in open field test (OFT. 6 hours after the last ethanol administration, seizure threshold was measured in all the groups by administering the convulsant drug, PTZ with a subconvulsive dose of 30 mg/kg i.p. In FST, mice were forced to swim and the total duration of immobility (seconds was measured during the last 4 min of a single 6-min test session. In OFT, number of crossings of the lines marked on the floor was recorded for a period of 5 min. Results: Compared to ethanol group, ASW (500 mg/Kg has suppressed the PTZ kindling seizures in ethanol withdrawal animals [0% convulsion], FST has shown decreased immobility time and OFT has exhibited increase in the number of line crossing activity by mice which may be the consequence of anxiolytic activity of ASW similar to that of diazepam. Conclusions: The present study provides satisfactory evidence to use ASW as a safe and reliable alternative to diazepam in alcohol withdrawal conditions.

  18. GIS habitat analysis for lesser prairie-chickens in southeastern New Mexico

    Directory of Open Access Journals (Sweden)

    Neville Paul

    2006-12-01

    Full Text Available Abstract Background We conducted Geographic Information System (GIS habitat analyses for lesser prairie-chicken (LPCH, Tympanuchus pallidicinctus conservation planning. The 876,799 ha study area included most of the occupied habitat for the LPCH in New Mexico. The objectives were to identify and quantify: 1. suitable LPCH habitat in New Mexico, 2. conversion of native habitats, 3. potential for habitat restoration, and 4. unsuitable habitat available for oil and gas activities. Results We found 16% of suitable habitat (6% of the study area distributed in 13 patches of at least 3,200 ha and 11% of suitable habitat (4% of the study area distributed in four patches over 7,238 ha. The area converted from native vegetation types comprised 17% of the study area. Ninety-five percent of agricultural conversion occurred on private lands in the northeastern corner of the study area. Most known herbicide-related conversions (82% occurred in rangelands in the western part of the study area, on lands managed primarily by the US Bureau of Land Management (BLM. We identified 88,190 ha (10% of the study area of habitats with reasonable restoration potential. Sixty-two percent of the primary population area (PPA contained occupied, suitable, or potentially suitable habitat, leaving 38% that could be considered for oil and gas development. Conclusion Although suitable LPCH habitat appears at first glance to be abundant in southeastern New Mexico, only a fraction of apparently suitable vegetation types constitute quality habitat. However, we identified habitat patches that could be restored through mesquite control or shin-oak reintroduction. The analysis also identified areas of unsuitable habitat with low restoration potential that could be targeted for oil and gas exploration, in lieu of occupied, high-quality habitats. Used in combination with GIS analysis and current LPCH population data, the habitat map represents a powerful conservation and management tool.

  19. GIS habitat analysis for lesser prairie-chickens in southeastern New Mexico.

    Science.gov (United States)

    Johnson, Kristine; Neville, Teri B; Neville, Paul

    2006-12-04

    We conducted Geographic Information System (GIS) habitat analyses for lesser prairie-chicken (LPCH, Tympanuchus pallidicinctus) conservation planning. The 876,799 ha study area included most of the occupied habitat for the LPCH in New Mexico. The objectives were to identify and quantify: 1. suitable LPCH habitat in New Mexico, 2. conversion of native habitats, 3. potential for habitat restoration, and 4. unsuitable habitat available for oil and gas activities. We found 16% of suitable habitat (6% of the study area) distributed in 13 patches of at least 3,200 ha and 11% of suitable habitat (4% of the study area) distributed in four patches over 7,238 ha. The area converted from native vegetation types comprised 17% of the study area. Ninety-five percent of agricultural conversion occurred on private lands in the northeastern corner of the study area. Most known herbicide-related conversions (82%) occurred in rangelands in the western part of the study area, on lands managed primarily by the US Bureau of Land Management (BLM). We identified 88,190 ha (10% of the study area) of habitats with reasonable restoration potential. Sixty-two percent of the primary population area (PPA) contained occupied, suitable, or potentially suitable habitat, leaving 38% that could be considered for oil and gas development. Although suitable LPCH habitat appears at first glance to be abundant in southeastern New Mexico, only a fraction of apparently suitable vegetation types constitute quality habitat. However, we identified habitat patches that could be restored through mesquite control or shin-oak reintroduction. The analysis also identified areas of unsuitable habitat with low restoration potential that could be targeted for oil and gas exploration, in lieu of occupied, high-quality habitats. Used in combination with GIS analysis and current LPCH population data, the habitat map represents a powerful conservation and management tool.

  20. 77 FR 55225 - Notice of Public Meeting, Las Cruces District Resource Advisory Council Meeting, New Mexico

    Science.gov (United States)

    2012-09-07

    ... deaf (TDD) may call the Federal Information Relay Service (FIRS) at 1-800-877-8229 to contact the above... variety of planning and management issues associated with public land management in New Mexico. Planned...

  1. 77 FR 18858 - Notice of Public Meeting, Las Cruces District Resource Advisory Council Meeting, New Mexico

    Science.gov (United States)

    2012-03-28

    ... deaf (TDD) may call the Federal Information Relay Service (FIRS) at 1-800-877-8229 to contact the above... variety of planning and management issues associated with public land management in New Mexico. Planned...

  2. USA Withdrawal from Paris Agreement – What Next?

    OpenAIRE

    Sergey Chestnoy; Dinara Gershinkova

    2017-01-01

    In June 2017, President Trump announced the USA’s withdrawal from the Paris Climate Accord, which had been ratified for less than a year, thanks in large part to the USA. That drastic shift followed the change in residency at the White House. Withdrawing from the Paris Accord presents an interesting topic for analysis. There’s the practical side of the withdrawal procedure as set out in Article 28 of the agreement, not to mention the consequences of US non-participation in address...

  3. Cocaine withdrawal causes delayed dysregulation of stress genes in the hippocampus.

    Directory of Open Access Journals (Sweden)

    M Julia García-Fuster

    Full Text Available Relapse, even following an extended period of withdrawal, is a major challenge in substance abuse management. Delayed neurobiological effects of the drug during prolonged withdrawal likely contribute to sustained vulnerability to relapse. Stress is a major trigger of relapse, and the hippocampus regulates the magnitude and duration of stress responses. Recent work has implicated hippocampal plasticity in various aspects of substance abuse. We asked whether changes in stress regulatory mechanisms in the hippocampus may participate in the neuroadaptations that occur during prolonged withdrawal. We therefore examined changes in the rat stress system during the course of withdrawal from extended daily access (5-hours of cocaine self-administration, an animal model of addiction. Tissue was collected at 1, 14 and 28 days of withdrawal. Plasma corticosterone levels were determined and corticosteroid receptors (GR, MR, MR/GR mRNA ratios and expression of other stress-related molecules (HSP90AA1 and HSP90AB1 mRNA were measured in hippocampal subfields using in situ hybridization. Results showed a delayed emergence of dysregulation of stress genes in the posterior hippocampus following 28 days of cocaine withdrawal. This included increased GR mRNA in DG and CA3, increased MR and HSP90AA1 mRNA in DG, and decreased MR/GR mRNA ratio in DG and CA1. Corticosterone levels progressively decreased during the course of withdrawal, were normalized following 28 days of withdrawal, and were correlated negatively with GR and positively with MR/GR mRNA ratio in DG. These results suggest a role for the posterior hippocampus in the neuroadaptations that occur during prolonged withdrawal, and point to a signaling partner of GR, HSP90AA1, as a novel dysregulated target during cocaine withdrawal. These delayed neurobiological effects of extended cocaine exposure likely contribute to sustained vulnerability to relapse.

  4. Chronic agmatine treatment prevents behavioral manifestations of nicotine withdrawal in mice.

    Science.gov (United States)

    Kotagale, Nandkishor R; Chopde, Chandrabhan T; Umekar, Milind J; Taksande, Brijesh G

    2015-05-05

    Smoking cessation exhibits an aversive withdrawal syndrome characterized by both increases in somatic signs and affective behaviors including anxiety and depression. In present study, abrupt withdrawal of daily nicotine injections (2mg/kg, s.c., four times daily, for 10 days) significantly increased somatic signs viz. rearing, grooming, jumping, genital licking, leg licking, head shakes with associated depression (increased immobility in forced swim test) as well as anxiety (decreased the number of entries and time spent in open arm in elevated plus maze) in nicotine dependent animals. The peak effect was observed at 24h time point of nicotine withdrawal. Repeated administration of agmatine (40-80µg/mouse, i.c.v.) before the first daily dose of nicotine from day 5 to 10 attenuated the elevated scores of somatic signs and abolished the depression and anxiety like behavior induced by nicotine withdrawal in dependent animals. However, in separate groups, its acute administration 30min before behavior analysis of nicotine withdrawal was ineffective. This result clearly shows the role of agmatine in development of nicotine dependence and its withdrawal. In extension to behavioral experiments, brain agmatine analyses, carried out at 24h time point of nicotine withdrawal demonstrated marked decrease in basal brain agmatine concentration as compared to control animals. Taken together, these data support the role of agmatine as common biological substrate for somatic signs and affective symptoms of nicotine withdrawal. This data may project therapies based on agmatine in anxiety, depression and mood changes associated with tobacco withdrawal. Copyright © 2015 Elsevier B.V. All rights reserved.

  5. Ketogenic Diet suppresses Alcohol Withdrawal Syndrome in Rats

    DEFF Research Database (Denmark)

    Dencker, Ditte; Molander, Anna; Thomsen, Morgane

    2018-01-01

    , we investigated the potential therapeutic benefit of a ketogenic diet in managing alcohol withdrawal symptoms during detoxification. METHODS: Male Sprague Dawley rats fed either ketogenic or regular diets were administered ethanol or water orally, twice daily for 6 days while the diet conditions were...... maintained. Abstinence symptoms were rated 6, 24, 48, and 72 hours after the last alcohol administration. RESULTS: Maintenance on a ketogenic diet caused a significant decrease in the alcohol withdrawal symptoms 'rigidity' and 'irritability'. CONCLUSION: Our preclinical pilot study suggests that a ketogenic...... diet may be a novel approach for treating alcohol withdrawal symptoms in humans. This article is protected by copyright. All rights reserved....

  6. Emergence of dormant conditioned incentive approach by conditioned withdrawal in nicotine addiction.

    Science.gov (United States)

    Scott, Daniel; Hiroi, Noboru

    2010-10-15

    Nicotine is one of the determinants for the development of persistent smoking, and this maladaptive behavior is characterized by many symptoms, including withdrawal and nicotine seeking. The process by which withdrawal affects nicotine seeking is poorly understood. The impact of a withdrawal-associated cue on nicotine (.2 mg/kg)-conditioned place preference was assessed in male C57BL/6J mice (n = 8-17/group). To establish a cue selectively associated with withdrawal distinct from those associated with nicotine, a tone was paired with withdrawal in their home cages; mice were chronically exposed to nicotine (200 μg/mL for 15 days) from drinking water in their home cages and received the nicotinic acetylcholine receptor antagonist mecamylamine (2.5 mg/kg) to precipitate withdrawal in the presence of a tone. The effect of the withdrawal-associated tone on nicotine-conditioned place preference was then evaluated in the place-conditioning apparatus after a delay, when nicotine-conditioned place preference spontaneously disappeared. A cue associated with precipitated withdrawal reactivated the dormant effect of nicotine-associated cues on conditioned place preference. This effect occurred during continuous exposure to nicotine but not during abstinence. A conditioned withdrawal cue could directly amplify the incentive properties of cues associated with nicotine. This observation extends the contemporary incentive account of the role of withdrawal in addiction to cue-cue interaction. Copyright © 2010 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.

  7. Time-course of the DSM-5 cannabis withdrawal symptoms in poly-substance abusers

    DEFF Research Database (Denmark)

    Hesse, Morten; Thylstrup, Birgitte

    2013-01-01

    Background Evidence is accumulating that a cannabis withdrawal syndrome is common, of clinical significance, and has a clear time course. Up till now, very limited data exist on the cannabis withdrawal symptoms in patients with co-morbid substance use disorders, other than cannabis use and tobacco...... the DSM-5 Withdrawal Symptom Check List with withdrawal symptoms from all classes of substances, with no indication that the described symptoms should be attributed to withdrawal. Self-reported time since last use of cannabis was used as a predictor of cannabis withdrawal severity. Results...... With the exception of loss of appetite, time since last use of cannabis was associated with all types of withdrawal symptoms listed in the DSM-5. Only four of 19 symptoms intended to measure withdrawal from other substances were related to time since last use of cannabis, including vivid, unpleasant dreams...

  8. Tolerance and withdrawal from prolonged opioid use in critically ill children.

    Science.gov (United States)

    Anand, Kanwaljeet J S; Willson, Douglas F; Berger, John; Harrison, Rick; Meert, Kathleen L; Zimmerman, Jerry; Carcillo, Joseph; Newth, Christopher J L; Prodhan, Parthak; Dean, J Michael; Nicholson, Carol

    2010-05-01

    After prolonged opioid exposure, children develop opioid-induced hyperalgesia, tolerance, and withdrawal. Strategies for prevention and management should be based on the mechanisms of opioid tolerance and withdrawal. Relevant manuscripts published in the English language were searched in Medline by using search terms "opioid," "opiate," "sedation," "analgesia," "child," "infant-newborn," "tolerance," "dependency," "withdrawal," "analgesic," "receptor," and "individual opioid drugs." Clinical and preclinical studies were reviewed for data synthesis. Mechanisms of opioid-induced hyperalgesia and tolerance suggest important drug- and patient-related risk factors that lead to tolerance and withdrawal. Opioid tolerance occurs earlier in the younger age groups, develops commonly during critical illness, and results more frequently from prolonged intravenous infusions of short-acting opioids. Treatment options include slowly tapering opioid doses, switching to longer-acting opioids, or specifically treating the symptoms of opioid withdrawal. Novel therapies may also include blocking the mechanisms of opioid tolerance, which would enhance the safety and effectiveness of opioid analgesia. Opioid tolerance and withdrawal occur frequently in critically ill children. Novel insights into opioid receptor physiology and cellular biochemical changes will inform scientific approaches for the use of opioid analgesia and the prevention of opioid tolerance and withdrawal.

  9. A double blind, within subject comparison of spontaneous opioid withdrawal from buprenorphine versus morphine.

    Science.gov (United States)

    Tompkins, D Andrew; Smith, Michael T; Mintzer, Miriam Z; Campbell, Claudia M; Strain, Eric C

    2014-02-01

    Preliminary evidence suggests that there is minimal withdrawal after the cessation of chronically administered buprenorphine and that opioid withdrawal symptoms are delayed compared with those of other opioids. The present study compared the time course and magnitude of buprenorphine withdrawal with a prototypical μ-opioid agonist, morphine. Healthy, out-of-treatment opioid-dependent residential volunteers (N = 7) were stabilized on either buprenorphine (32 mg/day i.m.) or morphine (120 mg/day i.m.) administered in four divided doses for 9 days. They then underwent an 18-day period of spontaneous withdrawal, during which four double-blind i.m. placebo injections were administered daily. Stabilization and spontaneous withdrawal were assessed for the second opioid using the same time course. Opioid withdrawal measures were collected eight times daily. Morphine withdrawal symptoms were significantly (P withdrawal as measured by mean peak ratings of Clinical Opiate Withdrawal Scale (COWS), Subjective Opiate Withdrawal Scale (SOWS), all subscales of the Profile of Mood States (POMS), sick and pain (0-100) Visual Analog Scales, systolic and diastolic blood pressure, heart rate, respiratory rate, and pupil dilation. Peak ratings on COWS and SOWS occurred on day 2 of morphine withdrawal and were significantly greater than on day 2 of buprenorphine withdrawal. Subjective reports of morphine withdrawal resolved on average by day 7. There was minimal evidence of buprenorphine withdrawal on any measure. In conclusion, spontaneous withdrawal from high-dose buprenorphine appears subjectively and objectively milder compared with that of morphine for at least 18 days after drug cessation.

  10. 75 FR 77658 - Public Land Order No. 7755; Withdrawal of Public Lands and Reserved Federal Minerals for the Ash...

    Science.gov (United States)

    2010-12-13

    ... mining laws (30 U.S.C. Ch. 2), and jurisdiction is transferred to the U.S. Fish and Wildlife Service for... mining laws, and 5,570.02 acres of reserved Federal minerals from location under the mining laws, subject.... This order also transfers jurisdiction of the public lands within the Ash Meadows National Wildlife...

  11. Assessment of current and proposed nature reserves of Mexico based on their capacity to protect geophysical features and biodiversity

    Science.gov (United States)

    Cantu, C.; Wright, R.G.; Scott, J.M.; Strand, Espen

    2004-01-01

    Mexico currently has 144 nature reserves covering approximately 9.1% of its land area. These reserves were established for a variety of reasons - often unrelated to the protection of biodiversity. In 2000 in response to a growing concern about the lack of organized conservation reserve planning to protect the important threatened biological and physical features of Mexico, the Mexican Commission for Knowledge and Use of Biodiversity (CONABIO) proposed the establishment of 151 new reserves for Mexico covering 51,429,500 ha. We compiled a GIS analysis using digital thematic maps of physical and biological features to examine how the existing and proposed reserves serve to protect the biodiversity and physical features of the country. Using a conservation target of placing a minimum of 12% of the land area of each important biophysical feature in nature reserves, we found that the 144 existing nature reserves covering 18 million ha (9% of the country) only meet that target for elevation ranges >3000 m and areas with poor soils. These mountainous areas represent less than 1% of the country. The gaps in the existing nature reserves network occur mainly at lower and intermediate elevations (<3000 m) areas with xeric, tropical, and temperate ecosystems, and high productivity soils. The areas proposed by CONABIO increase the proportion of protected lands in the country to over 27% and most of the conservation targets for geophysical features, and land cover, categories are met. Whether this area would be sufficient to maintain viable populations and ecological integrity of species and ecosystems is unknown. Even with the new reserves, low elevation coastal lands would be below the conservation target in the nature reserves. To include a representative sample of these lands would be difficult as these are the same areas where the majority of people live. ?? 2003 Elsevier Ltd. All rights reserved.

  12. The Study of the Role of Contributor Factors in Addiction Withdrawal

    Directory of Open Access Journals (Sweden)

    Omar Kianipour

    2012-08-01

    Full Text Available Introduction: The present paper investigated the factors contributing to addiction withdrawal so as to it would be possible to set preventive and rehabilitative programs for addicts. Method: The study was ex-post facto and causal-comparative one. Population included all addicts referred to addiction withdrawal centers of Kahnouj city and the sample was selected of addicts of Yaran addiction withdrawal Center by voluntary sampling. Bar-on emotional intelligence inventory, family boundary questionnaire and demographic information were administered among selected sample. Results: The results showed that normal family boundaries, higher emotional intelligence and opium use in comparison of crack and crystal glass are effective on addiction withdrawal. But disengaged family boundaries, crack and crystal glass use can be led to addiction recursion. Age, addiction duration, marital status, and education level are not effective on addiction withdrawal. Conclusion: Altogether, the results represented the role and importance of variables namely: family, emotional intelligence, and the kind of used material in addiction withdrawal.

  13. 20 CFR 410.232 - Withdrawal of a claim.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Withdrawal of a claim. 410.232 Section 410.232 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL COAL MINE HEALTH AND SAFETY ACT OF 1969... Claims and Evidence § 410.232 Withdrawal of a claim. (a) Before adjudication of claim. A claimant (or an...

  14. 12 CFR 563g.11 - Withdrawal or abandonment.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Withdrawal or abandonment. 563g.11 Section 563g.11 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY SECURITIES OFFERINGS § 563g.11 Withdrawal or abandonment. (a) Any offering circular, amendment, or exhibit may be withdrawn...

  15. 27 CFR 19.997 - Withdrawal of fuel alcohol.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Withdrawal of fuel alcohol. 19.997 Section 19.997 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU... and Transfers § 19.997 Withdrawal of fuel alcohol. For each shipment or other removal of fuel alcohol...

  16. Psychosocial withdrawal characteristics of nicotine compared with alcohol and caffeine.

    Science.gov (United States)

    Miyata, Hisatsugu; Hironaka, Naoyuki; Takada, Kohji; Miyasato, Katsumasa; Nakamura, Koichi; Yanagita, Tomoji

    2008-10-01

    The purpose of the present study was to observe the psychosocial characteristics of withdrawal from cigarette smoking in comparison with those from caffeine (CAF) and alcoholic (ALC) beverage withdrawal. Twenty-seven healthy volunteers at a medial level of dependence on both cigarettes (nicotine, NCT) and either CAF or ALC, as judged by the DSM-IV-TR criteria for substance dependence, participated in this study. The participants were required to abstain from smoking and either CAF or ALC for 7 days, each one after another, with a 7-day interval. The order of abstinence was counterbalanced among the participants. Psychosocial parameters, including a desire for substances, social activity function, well-being, withdrawal symptoms, and vital signs, were assessed during the withdrawal periods. The study protocol was approved by the Jikei University Review Board. The results indicated that there were no differences in the maximum level of desire for a substance and the influence on social activity function between NCT and other substances during the withdrawal periods. As for withdrawal symptoms, NCT caused a more intensive degree of irritability than CAF or ALC, and a more intensive degree of difficulty concentrating and restlessness than did withdrawal from ALC. However, the subjective well-being questionnaire indicated no differences in these symptoms between NCT and other substances. The present results suggest that there are no significant differences in psychosocial manifestations regarding the difficulty in abstaining from NCT, CAF, and ALC.

  17. The Treatment of Clozapine-Withdrawal Delirium with Electroconvulsive Therapy

    Directory of Open Access Journals (Sweden)

    Anish Modak

    2017-01-01

    Full Text Available Clozapine, a commonly used atypical antipsychotic, can precipitate a severe withdrawal syndrome. In this report, we describe a case of delirium with catatonic features emerging after the immediate cessation of clozapine subsequent to concerns of developing neuroleptic malignant syndrome. After multiple treatments were found to be inefficacious, electroconvulsive therapy (ECT was initiated, resulting in significant improvement. A literature search revealed six previous cases of clozapine-withdrawal syndromes of varied symptomatology treated with ECT. To our knowledge, the present case represents the first reported clozapine-withdrawal delirium treated successfully with ECT.

  18. Youth social withdrawal behavior (hikikomori): A systematic review of qualitative and quantitative studies.

    Science.gov (United States)

    Li, Tim M H; Wong, Paul W C

    2015-07-01

    Acute and/or severe social withdrawal behavior among youth was seen as a culture-bound psychiatric syndrome in Japan, but more youth social withdrawal cases in different countries have been discovered recently. However, due to the lack of a formal definition and diagnostic tool for youth social withdrawal, cross-cultural observational and intervention studies are limited. We aimed to consolidate existing knowledge in order to understand youth social withdrawal from diverse perspectives and suggest different interventions for different trajectories of youth social withdrawal. This review examined the current available scientific information on youth social withdrawal in the academic databases: ProQuest, ScienceDirect, Web of Science and PubMed. We included quantitative and qualitative studies of socially withdrawn youths published in English and academic peer-reviewed journals. We synthesized the information into the following categories: (1) definitions of youth social withdrawal, (2) developmental theories, (3) factors associated with youth social withdrawal and (4) interventions for socially withdrawn youths. Accordingly, there are diverse and controversial definitions for youth social withdrawal. Studies of youth social withdrawal are based on models that lead to quite different conclusions. Researchers with an attachment perspective view youth social withdrawal as a negative phenomenon, whereas those who adopt Erikson's developmental theory view it more positively as a process of seeking self-knowledge. Different interventions for socially withdrawn youths have been developed, mainly in Japan, but evidence-based practice is almost non-existent. We propose a theoretical framework that views youth social withdrawal as resulting from the interplay between psychological, social and behavioral factors. Future validation of the framework will help drive forward advances in theory and interventions for youth social withdrawal as an emerging issue in developed

  19. Access to serviced land for the urban poor: the regularization paradox in Mexico

    Directory of Open Access Journals (Sweden)

    Alfonso Iracheta Cenecorta

    2000-01-01

    Full Text Available The insufficient supply of serviced land at affordable prices for the urban poor and the need for regularization of the consequent illegal occupations in urban areas are two of the most important issues on the Latin American land policy agenda. Taking a structural/integrated view on the functioning of the urban land market in Latin America, this paper discusses the nexus between the formal and the informal land markets. It thus exposes the perverse feedback effects that curative regularization policies may have on the process by which irregularity is produced in the first place. The paper suggests that a more effective approach to the provision of serviced land for the poor cannot be resolved within the prevailing (curative regularization programs. These programs should have the capacity to mobilize the resources that do exist into a comprehensive program that links regularization with fiscal policy, including the exploration of value capture mechanisms.

  20. Smartphone Restriction and its Effect on Subjective Withdrawal Related Scores

    OpenAIRE

    Aarestad, Sarah Helene; Eide, Tine Almenning

    2017-01-01

    Smartphone overuse is associated with a number of negative consequences for the individual and the environment. In the right end of the distribution of smartphone usage, concepts such as smartphone addiction seem warranted. An area that so far lacks research concerns the effect of smartphone restriction generally and specifically on subjective withdrawal related scores across different degrees of smartphone usage. The present study examined withdrawal related scores on the Smartphone Withdraw...

  1. Using High-Resolution Satellite Aerosol Optical Depth To Estimate Daily PM2.5 Geographical Distribution in Mexico City.

    Science.gov (United States)

    Just, Allan C; Wright, Robert O; Schwartz, Joel; Coull, Brent A; Baccarelli, Andrea A; Tellez-Rojo, Martha María; Moody, Emily; Wang, Yujie; Lyapustin, Alexei; Kloog, Itai

    2015-07-21

    Recent advances in estimating fine particle (PM2.5) ambient concentrations use daily satellite measurements of aerosol optical depth (AOD) for spatially and temporally resolved exposure estimates. Mexico City is a dense megacity that differs from other previously modeled regions in several ways: it has bright land surfaces, a distinctive climatological cycle, and an elevated semi-enclosed air basin with a unique planetary boundary layer dynamic. We extend our previous satellite methodology to the Mexico City area, a region with higher PM2.5 than most U.S. and European urban areas. Using a novel 1 km resolution AOD product from the MODIS instrument, we constructed daily predictions across the greater Mexico City area for 2004-2014. We calibrated the association of AOD to PM2.5 daily using municipal ground monitors, land use, and meteorological features. Predictions used spatial and temporal smoothing to estimate AOD when satellite data were missing. Our model performed well, resulting in an out-of-sample cross-validation R(2) of 0.724. Cross-validated root-mean-squared prediction error (RMSPE) of the model was 5.55 μg/m(3). This novel model reconstructs long- and short-term spatially resolved exposure to PM2.5 for epidemiological studies in Mexico City.

  2. Climate change effects on central New Mexico's land use, transportation system, and key natural resources : task 1.2 memo

    Science.gov (United States)

    2014-05-01

    The purpose of this report is to illustrate how planning decisions made today will affect central New Mexicos resilience to climate change impacts in 2040. This report first describes climate change impacts in central New Mexico. This report then ...

  3. New information on regional subsidence and soil fracturing in Mexico City Valley

    Directory of Open Access Journals (Sweden)

    G. Auvinet

    2015-11-01

    Full Text Available In this paper, updated information about regional subsidence in Mexico City downtown area is presented. Data obtained by R. Gayol in 1891, are compared with information obtained recently from surveys using the reference points of Sistema de Aguas de la Ciudad de México (2008 and on the elevation of a cloud of points on the ground surface determined using Light Detection and Ranging (LiDAR technology. In addition, this paper provides an overview of recent data obtained from systematic studies focused on understanding soil fracturing associated with regional land subsidence and mapping of areas susceptible to cracking in Mexico City Valley.

  4. Financing options in Mexico`s energy industry

    Energy Technology Data Exchange (ETDEWEB)

    McKenna, J.J. [PricewaterhouseCoopers Securities, Houston, TX (United States)

    1999-10-01

    A series of brief notes accompanied this presentation which was divided into seven sections entitled: (1) capital markets update, (2) Mexican financial market update, (3) financing options in the energy industry, (4) the Venezuelan experience at La Apertura, (5) private and strategic equity alternatives, (6) Pricewaterhouse Coopers Securities, and (7) Mexico energy 2005 prediction. The paper focused on how the financial crisis and merger activity in Latin America will impact electricity reform in Mexico. It was noted that under Mexico`s Policy Proposal for Electricity Reform of the Mexican Electricity Industry, the financial community will seek to back companies in power generation, transportation and distribution. The difficulty of financing government businesses undergoing privatization was also discussed with particular emphasis on the challenge of accepting political and regulatory risks. The Latin private equity market and Canadian investment in Mexico was also reviewed. Since NAFTA (North American Free Trade Agreement) went into affect in 1994, Canadian investment in Mexico has more than tripled. Canadian companies have invested more than C$1.7 billion in Mexico since NAFTA. Pricewaterhouse Coopers Securities is a global investment bank which sees large opportunities in the Mexican energy market. They predict that in five years, Mexico will experience a gradual liberalization of the oil and gas sector, and a full liberalization of the gas pipeline and distribution business and the power generation, transmission and distribution business. 3 figs.

  5. 76 FR 38416 - Notice of Segregation of Public Lands in the States of Arizona, California, Colorado, Nevada, New...

    Science.gov (United States)

    2011-06-30

    ... Segregation of Public Lands in the States of Arizona, California, Colorado, Nevada, New Mexico, and Utah... laws, but not the mineral leasing or material sales acts, for a period of 2 years for the purpose of..., approximately 677,384 acres of public lands located in the States of Arizona, California, Colorado, Nevada, New...

  6. Land use changes and transnational migration: the impact of remittances in Western Mexico

    OpenAIRE

    Hostettler, Silvia

    2007-01-01

    The present study focuses on the economic, political/institutional, technological, cultural, demographic and environmental drivers of land use change. It aims to understand the factors influencing land use decisions at the household level, in particular the influence of migration. The study is guided by the hypothesis that international migration is driving land use change through the investment of remittances, funds sent back by migrants to their families in the country of origin. This resea...

  7. Land use changes and transnational migration: the impact of remittances in Western Mexico

    OpenAIRE

    Hostettler, Silvia; Bolay, Jean-Claude

    2008-01-01

    The present study focuses on the economic, political/institutional, technological, cultural, demographic and environmental drivers of land use change. It aims to understand the factors influencing land use decisions at the household level, in particular the influence of migration. The study is guided by the hypothesis that international migration is driving land use change through the investment of remittances, funds sent back by migrants to their families in the country of origin. This resea...

  8. The acute tobacco withdrawal syndrome among black smokers.

    Science.gov (United States)

    Robinson, Cendrine D; Pickworth, Wallace B; Heishman, Stephen J; Waters, Andrew J

    2014-03-01

    Black smokers have greater difficulty quitting tobacco than White smokers, but the mechanisms underlying between-race differences in smoking cessation are not clear. One possibility is that Black smokers experience greater acute withdrawal than Whites. We investigated whether Black (n = 104) and White smokers (n = 99) differed in abstinence-induced changes in self-report, physiological, and cognitive performance measures. Smokers not wishing to quit completed two counterbalanced experimental sessions. Before one session, they abstained from smoking for at least 12 hr. They smoked normally before the other session. Black smokers reported smaller abstinence-induced changes on a number of subjective measures including the total score of the 10-item Questionnaire for Smoking Urges (QSU) and the total score of the Wisconsin Smoking Withdrawal Scale (WSWS). However, on most subjective measures, and on all objective measures, there were no between-race differences in abstinence-induced change scores. Moreover, Black participants did not report lower QSU and WSWS ratings at the abstinent session, but they did experience significantly higher QSU and WSWS ratings at the nonabstinent session. Abstinence-induced changes in subjective, physiological, and cognitive measures in White smokers were similar for smokers of nonflavored and menthol-flavored cigarettes. There was no evidence that Black smokers experienced greater acute tobacco withdrawal than Whites. To the contrary, Black participants experienced smaller abstinence-induced changes in self-reported craving and withdrawal on some measures. Racial differences in smoking cessation are unlikely to be explained by acute withdrawal.

  9. 5 CFR 831.1207 - Withdrawal of disability retirement applications.

    Science.gov (United States)

    2010-01-01

    ... type. (d) OPM also considers a disability retirement application to be withdrawn when the agency... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Withdrawal of disability retirement...) CIVIL SERVICE REGULATIONS (CONTINUED) RETIREMENT Disability Retirement § 831.1207 Withdrawal of...

  10. How to expand irrigated land in a sustainable way ?

    Science.gov (United States)

    Pastor, Amandine V.; Ludwig, Fulco; Palazzo, Amanda; Havlik, Petr; Kabat, Pavel

    2015-04-01

    Allocation of agriculture commodities and water resources is subject to changes due to climate change, population increase and changes in dietary patterns. This study focused on including global water availability including environmental flow requirements with water withdrawal from irrigation and other sectors (industry, household and hydropower) at a monthly time-step in the GLOBIOM model. This model allows re-adjustment of land-use allocation, crop management, consumption and international trade. The GLOBIOM model induces an endogenous change in water price depending on water supply and demand. In this study, the focus was on how the inclusion of water resources affects land-use and, in particular, how global change will influence repartition of irrigated and rainfed lands at global scale. We used the climate change scenario including a radiative forcing of 2.6 W/m2 (RCP2.6), the socio-economic scenario (SSP2: middle-of-road), and the environmental flow method based on monthly flow allocation (the Variable Monthly Flow method) with high and low restrictions. Irrigation withdrawals were adjusted to a monthly time-step to account for biophysical water limitations at finer time resolution. Our results show that irrigated land might decrease up to 37% on average depending on the choice of EFR restrictions. Several areas were identified as future hot-spots of water stress such as the Mediterranean and Middle-East regions and parts of South-East Asia where the Water Stress Indicator (WSI) ranges from 0.4 to 1 by 2050. Other countries were identified to be in safe position in terms of water stress such as North-European countries. Some countries such as India expect a significant increase in water demand which might be compensated by an increase in water supply with climate change scenario. Re-allocation of rainfed and irrigated land might be useful information for land-use planners and water managers at an international level to decide on appropriate legislations on

  11. Opioid withdrawal signs and symptoms in children: frequency and determinants.

    Science.gov (United States)

    Fisher, Deborah; Grap, Mary Jo; Younger, Janet B; Ameringer, Suzanne; Elswick, R K

    2013-01-01

    The purpose of this study was to, in a pediatric population, describe the frequency of opioid withdrawal signs and symptoms and to identify factors associated with these opioid withdrawal signs and symptoms. Opioids are used routinely in the pediatric intensive care population for analgesia, sedation, blunting of physiologic responses to stress, and safety. In children, physical dependence may occur in as little as 2-3 days of continuous opioid therapy. Once the child no longer needs the opioid, the medications are reduced over time. A prospective, descriptive study was conducted. The sample of 26 was drawn from all patients, ages 2 weeks to 21 years admitted to the Children's Hospital of Richmond pediatric intensive care unit (PICU) and who have received continuous infusion or scheduled opioids for at least 5 days. Data collected included: opioid withdrawal score (WAT-1), opioid taper rate (total dose of opioid per day in morphine equivalents per kilogram [MEK]), pretaper peak MEK, pretaper cumulative MEK, number of days of opioid exposure prior to taper, and age. Out of 26 enrolled participants, only 9 (45%) had opioid withdrawal on any given day. In addition, there was limited variability in WAT-1 scores. The most common symptoms notes were diarrhea, vomit, sweat, and fever. For optimal opioid withdrawal assessments, clinicians should use a validated instrument such as the WAT-1 to measure for signs and symptoms of opioid withdrawal. Further research is indicated to examine risk factors for opioid withdrawal in children. Copyright © 2013 Elsevier Inc. All rights reserved.

  12. Survey of lands held for uranium exploration, development and production in fourteen western states in the six month period ending June 30, 1976

    International Nuclear Information System (INIS)

    1976-01-01

    Tabulated data are presented to show the land distribution by ownership, distribution by states, distribution by land category, acres held by uranium industry, and land control by county and state. The states surveyed are Arizona, California, Colorado, Idaho, Montana, Nevada, New Mexico, North Dakota, Oregon, South Dakota, Texas, Utah, Washington, and Wyoming

  13. Evaluation of a New Strategy for Attending Takeoffs and Landings to Reduce Aircraft Operating Costs and Passenger Delays at the Mexico City International Airport

    Directory of Open Access Journals (Sweden)

    Herrera-García Alfonso

    2014-01-01

    Full Text Available The objective of this research was to evaluate a strategy for attending the takeoffs and landings at a congested airport, in order to reduce aircraft operating costs and passenger delay times. The continuous growth of air transport activity has created congestion at major airports worldwide, this situation produces increases in the aircraft operating costs and passenger discomfort. In the strategy evaluated the traditional rule for attending to aircraft, on a first-come-first-served basis, was substituted with a sequence that reduces operating costs and passenger delays. In order to perform this evaluation a discrete-event simulation model was developed for the Mexico City International Airport. Results showed that it is possible to obtain significant benefits if the proposed strategy is applied, an annual benefit of around 28.6 million pesos could be achieved.

  14. U.S. withdrawal from the Paris Agreement: Reasons, impacts, and China's response

    OpenAIRE

    Hai-Bin Zhang; Han-Cheng Dai; Hua-Xia Lai; Wen-Tao Wang

    2017-01-01

    Applying qualitative and quantitative methods, this article explains the driving forces behind U.S. President Donald Trump's decision to withdraw from the Paris Agreement, assesses the impacts of this withdrawal on the compliance prospects of the agreement, and proposes how China should respond. The withdrawal undercuts the foundation of global climate governance and upsets the process of climate cooperation, and the impacts are manifold. The withdrawal undermines the universality of the Pari...

  15. Mexico Geoid Heights (MEXICO97)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This 2' geoid height grid for Mexico, and North-Central America, is the MEXICO97 geoid model. The computation used about one million terrestrial and marine gravity...

  16. Phenobarbital compared to benzodiazepines in alcohol withdrawal treatment

    DEFF Research Database (Denmark)

    Askgaard, Gro; Hallas, Jesper; Fink-Jensen, Anders

    2016-01-01

    BACKGROUND: Long-acting benzodiazepines such as chlordiazepoxide are recommended as first-line treatment for alcohol withdrawal. These drugs are known for their abuse liability and might increase alcohol consumption among problem drinkers. Phenobarbital could be an alternative treatment option......, possibly with the drawback of a more pronounced acute toxicity. We evaluated if phenobarbital compared to chlordiazepoxide decreased the risk of subsequent use of benzodiazepines, alcohol recidivism and mortality. METHODS: The study was a register-based cohort study of patients admitted for alcohol...... withdrawal 1998-2013 and treated with either phenobarbital or chlordiazepoxide. Patients were followed for one year. We calculated hazard ratios (HR) for benzodiazepine use, alcohol recidivism and mortality associated with alcohol withdrawal treatment, while adjusting for confounders. RESULTS: A total...

  17. Feasibility Study of Economics and Performance of Solar Photovoltaics at the Chino Mine in Silver City, New Mexico. A Study Prepared in Partnership with the Environmental Protection Agency for the RE-Powering America's Land Initiative: Siting Renewable Energy on Potentially Contaminated Land and Mine Sites

    Energy Technology Data Exchange (ETDEWEB)

    Kiatreungwattana, K.; Geiger, J.; Healey, V.; Mosey, G.

    2013-04-01

    The U.S. Environmental Protection Agency (EPA), in accordance with the RE-Powering America's Land initiative, selected the Chino Mine site in Silver City, New Mexico, for a feasibility study of renewable energy production. The National Renewable Energy Laboratory (NREL) provided technical assistance for this project. The purpose of this report is to assess the site for a possible photovoltaic (PV) system installation and estimate the cost, performance, and site impacts of different PV options. In addition, the report recommends financing options that could assist in the implementation of a PV system at the site.

  18. Assessing the Impact of Population Growth, Climate Change, and Land Use Change on Water Resources in India

    Science.gov (United States)

    Singh, N.; Cherkauer, K. A.

    2014-12-01

    India is poised to become the most populous country in the world by 2019 and reach a population of over 2 billion by 2050 based on current growth rates. It is also a region which will be under severe socio-economic and environmental stress if mitigation efforts are not adapted. In the past 10 years the population of India has grown by an average rate of 17 million people per year. In addition to unprecedented population growth, rapid urbanization and industrialization are straining the overburdened environmental system. This rapid growth in population, urbanization and industrialized will result in increased demand for food, requiring expansion of agricultural resources. Since total agricultural land in India has been relatively constant over the past 10 years the demand for additional food has to be partly met by enhanced production on existing land. Arable land in India has declined by around 3% according to FAOSTAT while the total agricultural area under irrigation has increased by about 9% thus further straining its water resources. In addition projections for future climate indicate that India is one of the regions where water resources are expected to be negatively impacted. Total agriculture water withdrawal in India increased by approximately 18 % from 2000-2010 while the total per capita water withdrawal increased by over 9% from 2000-2010. Total freshwater withdrawal as percentage of renewable water resources was around 40% in 2010. In addition, recent mandates of biofuel policies in India are also expected to impact its water resources. The combined impact of these various factors on future water availability in India could be one of the most severe globally due its unprecedented increase in population, food production and industrialization. In this study we assess the impact of land use and climate change on water resources over southern India in the face of a growing population and interest in development of national biofuel supplies. We use

  19. Land-use and land-cover assessment for the study of lifestyle change in a rural Mexican community: The Maycoba Project

    Directory of Open Access Journals (Sweden)

    Giraldo Mario A

    2012-07-01

    Full Text Available Abstract Background In 1995, a study was conducted to identify the effects of traditional and westernized environments on the prevalence of type 2 diabetes in Pima Indians (Pimas in Mexico and the United States. The study concluded that the more traditional lifestyle in Mexico had a protective effect against this metabolic disorder. In the ensuing 15 years, the environmental circumstances of the Mexican Pimas changed, and a follow-up study was conducted to determine the role environmental change plays in the development of diabetes in this genetically susceptible population. A major element of environmental transition relates to land-use and land-cover (LULC changes that could affect physical activity and promote an obesogenic environment. This study examined changes in the region’s LULC to determine whether there have been transitions in agricultural land use and urbanization that would be consistent with a more sedentary lifestyle. Changes were assessed from 1994 aerial photographs and 2007 satellite images. Results The land-cover analysis showed that mixed vegetation and dense trees cover most of the study area. It suggested a rural environment that includes a low percentage of impermeable areas, and it indicated that the area experiencing human intervention covers 7% of the total area. The land-use-change findings showed a decrease or no change in agricultural or ranching areas and a decrease in farmland due to reforestation or revegetation. Three variables from the land-use-change analysis were examined as proxies for lifestyle change: urban development, dwelling-unit density, and variation in the road network. Two of the measures –the amount of urbanization and the number and density of dwelling units—showed increases, most notably in the town of Maycoba. There were only minor changes in the road network: most of the road segments are short and concentrated in Maycoba where most of the buildings, points of interest (e.g., church

  20. 75 FR 12804 - Withdrawal of Regulatory Guide 8.6

    Science.gov (United States)

    2010-03-17

    ... ``Regulatory Guides'' in the NRC's Electronic Reading Room at http://www.nrc.gov/reading-rm/doc-collections... NUCLEAR REGULATORY COMMISSION [NRC-2010-0103] Withdrawal of Regulatory Guide 8.6 AGENCY: Nuclear Regulatory Commission. ACTION: Withdrawal of Regulatory Guide 8.6, ``Standard Test Procedure for Geiger-M...

  1. 40 CFR 180.8 - Withdrawal of petitions without prejudice.

    Science.gov (United States)

    2010-07-01

    ... prejudice. 180.8 Section 180.8 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... § 180.8 Withdrawal of petitions without prejudice. In some cases the Administrator will notify the... clarification or the obtaining of additional data. This withdrawal may be without prejudice to a future filing...

  2. An extended multivariate framework for drought monitoring in Mexico

    Science.gov (United States)

    Real-Rangel, Roberto; Pedrozo-Acuña, Adrián; Breña-Naranjo, Agustín; Alcocer-Yamanaka, Víctor

    2017-04-01

    Around the world, monitoring natural hazards, such as droughts, represents a critical task in risk assessment and management plans. A reliable drought monitoring system allows to identify regions affected by these phenomena so that early response measures can be implemented. In Mexico, this activity is performed using Mexico's Drought Monitor, which is based on a similar methodology as the United States Drought Monitor and the North American Drought Monitor. The main feature of these monitoring systems is the combination of ground-based and remote sensing observations that is ultimately validated by local experts. However, in Mexico in situ records of variables such as precipitation and streamflow are often scarce, or even null, in many regions of the country. Another issue that adds uncertainty in drought monitoring is the arbitrary weight given to each analyzed variable. This study aims at providing an operational framework for drought monitoring in Mexico, based on univariate and multivariate nonparametric standardized indexes proposed in recent studies. Furthermore, the framework has been extended by taking into account the Enhanced Vegetation Index (EVI) for the drought severity assessment. The analyzed variables used for computing the drought indexes are mainly derived from remote sensing (MODIS) and land surface models datasets (NASA MERRA-2). A qualitative evaluation of the results shows that the indexes used are capable of adequately describes the intensity and spatial distribution of past drought documented events.

  3. Caffeine withdrawal symptoms and self-administration following caffeine deprivation.

    Science.gov (United States)

    Mitchell, S H; de Wit, H; Zacny, J P

    1995-08-01

    This study examined the effects of complete or partial caffeine deprivation on withdrawal symptomatology and self-administration of coffee in caffeine-dependent coffee drinkers. Nine habitual coffee drinkers abstained from dietary sources of caffeine for 33.5 h. Caffeine deprivation was manipulated by administering capsules containing 0%, 50%, or 100% of each subject's daily caffeine intake (complete, partial, and no deprivation conditions). Caffeine withdrawal symptomatology was measured using self-report questionnaires. Caffeine self-administration was measured using: i) the amount of coffee subjects earned on a series of concurrent random-ratio schedules that yielded coffee and money reinforcers; ii) the amount of earned coffee they consumed. Saliva samples revealed that subjects complied with the caffeine abstinence instructions. Caffeine withdrawal symptoms occurred reliably following complete caffeine deprivation, though not in the partial deprivation condition. Caffeine self-administration was not related to deprivation condition. We conclude that caffeine withdrawal symptomatology is not necessarily associated with increased caffeine consumption.

  4. Steroid withdrawal in renal transplant patients: the Irish experience.

    LENUS (Irish Health Repository)

    Phelan, P J

    2012-02-01

    BACKGROUND: Steroid therapy is associated with significant morbidity in renal transplant recipients. However, there is concern that steroid withdrawal will adversely affect outcome. METHODS: We report on 241 renal transplant recipients on different doses of corticosteroids at 3 months (zero, <\\/= 5 mg\\/day, > 5 mg\\/day). Parameters analysed included blood pressure, lipid profile, weight change, new onset diabetes after transplantation (NODAT), allograft survival and acute rejection. RESULTS: Elimination of corticosteroids had no impact on allograft survival at 1 year. There were no cases of NODAT in the steroid withdrawal group compared with over 7% in each of the steroid groups. There were no significant improvements in weight gain, blood pressure control or total cholesterol with withdrawal of steroids before 3 months. CONCLUSIONS: In renal transplant patients treated with tacrolimus and mycophenolate, early withdrawal of steroids does not appear to adversely affect allograft outcome at 1 year. It may result in less NODAT.

  5. Steroid withdrawal in renal transplant patients: the Irish experience.

    LENUS (Irish Health Repository)

    Phelan, P J

    2010-10-29

    BACKGROUND: Steroid therapy is associated with significant morbidity in renal transplant recipients. However, there is concern that steroid withdrawal will adversely affect outcome. METHODS: We report on 241 renal transplant recipients on different doses of corticosteroids at 3 months (zero, ≤5 mg\\/day, >5 mg\\/day). Parameters analysed included blood pressure, lipid profile, weight change, new onset diabetes after transplantation (NODAT), allograft survival and acute rejection. RESULTS: Elimination of corticosteroids had no impact on allograft survival at 1 year. There were no cases of NODAT in the steroid withdrawal group compared with over 7% in each of the steroid groups. There were no significant improvements in weight gain, blood pressure control or total cholesterol with withdrawal of steroids before 3 months. CONCLUSIONS: In renal transplant patients treated with tacrolimus and mycophenolate, early withdrawal of steroids does not appear to adversely affect allograft outcome at 1 year. It may result in less NODAT.

  6. Determination of Screw and Nail Withdrawal Resistance of Some Important Wood Species

    Directory of Open Access Journals (Sweden)

    Alper Aytekin

    2008-04-01

    Full Text Available In this study, screw and nail withdrawal resistance of fir (Abies nordmanniana, oak (Quercus robur L. black pine (Pinus nigra Arnold and Stone pine (Pinus pinea L. wood were determined and compared. The data represent the testing of withdrawal resistance of three types of screws as smart, serrated and conventional and common nails. The specimens were prepared according to TS 6094 standards. The dimensions of the specimens were 5x5x15cm and for all of the directions. Moreover, the specimens were conditioned at ambient room temperature and 65±2% relative humidity. The screws and nails were installed according to ASTM-D 1761 standards. Nail dimensions were 2.5mm diameter and 50 mm length, conventional screws were 4x50mm, serrated screws were 4x45mm and smart screws were 4x50mm. Results show that the maximum screw withdrawal resistance value was found in Stone pine for the serrated screw. There were no significant differences between Stone pine and oak regarding screw withdrawal resistance values. Conventional screw yielded the maximum screw withdrawal resistance value in oak, followed by Stone pine, black pine and fir. Oak wood showed the maximum screw withdrawal resistance value for the smart screw, followed by Stone pine, black pine, and fir. Oak wood showed higher nail withdrawal resistances than softwood species. It was also determined that oak shows the maximum nail withdrawal resistance in all types. The nail withdrawal resistances at the longitudinal direction are lower with respect to radial and tangential directions.

  7. A genetic perspective on the proposed inclusion of cannabis withdrawal in the DSM-5

    Science.gov (United States)

    Verweij, K.J.H.; Agrawal, A.; Nat, N.O.; Creemers, H.E.; Huizink, A.C.; Martin, N.G.; Lynskey, M.T.

    2013-01-01

    Background Various studies support the inclusion of cannabis withdrawal to the diagnosis of cannabis use disorders in the upcoming DSM-5. The aims of the current study were to (1) estimate the prevalence of DSM-5 cannabis withdrawal (Criterion B), (2) estimate the role of genetic and environmental influences on individual differences in cannabis withdrawal, and (3) determine the extent to which genetic and environmental influences on cannabis withdrawal overlap with those on DSM-IV defined abuse/dependence. Methods The sample included 2276 lifetime cannabis-using adult Australian twins. Cannabis withdrawal was defined in accordance with Criterion B of the proposed DSM-5 revisions. Cannabis abuse/dependence was defined as endorsing one or more DSM-IV criteria of abuse or three or more dependence criteria. The classical twin model was used to estimate the genetic and environmental influences on variation in cannabis withdrawal, as well as its covariation with abuse/dependence. Results Of all cannabis users 11.9% met criteria for cannabis withdrawal. Around 50% of between-individual variation in withdrawal could be attributed to additive genetic variation, and the rest of the variation was mostly due to non-shared environmental influences. Importantly, the genetic influences on cannabis withdrawal almost completely (99%) overlapped with those on abuse/dependence. Conclusions We showed that cannabis withdrawal symptoms exist among cannabis users, and that cannabis withdrawal is moderately heritable. Genetic influences on cannabis withdrawal are the same as those influencing abuse/dependence. These results add to the wealth of literature that recommends the addition of cannabis withdrawal to the diagnosis of DSM-5 cannabis use disorders. PMID:23194657

  8. The environmental cost of a reference withdrawal from surface waters: Definition and geography

    Science.gov (United States)

    Soligno, Irene; Ridolfi, Luca; Laio, Francesco

    2017-12-01

    World freshwater ecosystems are significantly deteriorating at a faster rate than other ecosystems. Water withdrawals are recognized as one of the main drivers of growing water stress in river basins worldwide. Over the years, much effort has been devoted to quantify water withdrawals at a global scale; however, comparisons are not simple because the uneven spatiotemporal distribution of surface water resources entails that the same amount of consumed water does not have the same environmental cost in different times or places. In order to account for this spatiotemporal heterogeneity, this work proposes a novel index to assess the environmental cost of a withdrawal from a generic river section. The index depends on (i) the environmental relevance of the impacted fluvial ecosystem (e.g., bed-load transport capacity, width of the riparian belt, biodiversity richness) and (ii) the downstream river network affected by the water withdrawal. The environmental cost has been estimated in each and every river section worldwide considering a reference withdrawal. Being referred to a unitary reference withdrawal that can occur in any river section worldwide, our results can be suitably arranged for describing any scenario of surface water consumption (i.e., as the superposition of the actual pattern of withdrawals). The index aims to support the interpretation of the volumetric measure of surface water withdrawal with a perspective that takes into account the fluvial system where the withdrawal actually occurs. The application of the index highlights the river regions where withdrawals can cause higher environmental costs, with the challenge of weighting each water withdrawal considering the responsibilities that it has on downstream freshwater ecosystems.

  9. Opioid withdrawal suppression efficacy of oral dronabinol in opioid dependent humans.

    Science.gov (United States)

    Lofwall, Michelle R; Babalonis, Shanna; Nuzzo, Paul A; Elayi, Samy Claude; Walsh, Sharon L

    2016-07-01

    The cannabinoid (CB) system is a rational novel target for treating opioid dependence, a significant public health problem around the world. This proof-of-concept study examined the potential efficacy of a CB1 receptor partial agonist, dronabinol, in relieving signs and symptoms of opioid withdrawal. Twelve opioid dependent adults participated in this 5-week, inpatient, double-blind, randomized, placebo-controlled study. Volunteers were maintained on double-blind oxycodone (30mg oral, four times/day) and participated in a training session followed by 7 experimental sessions, each testing a single oral test dose (placebo, oxycodone 30 and 60mg, dronabinol 5, 10, 20, and 30mg [decreased from 40mg]). Placebo was substituted for oxycodone maintenance doses for 21h before each session in order to produce measurable opioid withdrawal. Outcomes included observer- and participant-ratings of opioid agonist, opioid withdrawal and psychomotor/cognitive performance. Oxycodone produced prototypic opioid agonist effects (i.e. suppressing withdrawal and increasing subjective effects indicative of abuse liability). Dronabinol 5 and 10mg produced effects most similar to placebo, while the 20 and 30mg doses produced modest signals of withdrawal suppression that were accompanied by dose-related increases in high, sedation, bad effects, feelings of heart racing, and tachycardia. Dronabinol was not liked more than placebo, showed some impairment in cognitive performance, and was identified as marijuana with increasing dose. CB1 receptor activation is a reasonable strategy to pursue for the treatment of opioid withdrawal; however, dronabinol is not a likely candidate given its modest withdrawal suppression effects of limited duration and previously reported tachycardia during opioid withdrawal. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  10. Caffeine, sleep and wakefulness: implications of new understanding about withdrawal reversal.

    Science.gov (United States)

    James, Jack E; Keane, Michael A

    2007-12-01

    The broad aim of this review is to critically examine the implications of new understanding concerning caffeine withdrawal and withdrawal reversal in the context of research concerned with the effects of caffeine on sleep and wakefulness. A comprehensive search was conducted for relevant experimental studies in the PubMED and PsycINFO databases. Studies were assessed with particular reference to methodological adequacy for controlling against confounding due to caffeine withdrawal and withdrawal reversal. This assessment was used to clarify evidence of effects, highlight areas of ambiguity and derive recommendations for future research. It was found that researchers have generally failed to take account of the fact that habitual use of caffeine, even at moderate levels, leads to physical dependence evidenced by physiological, behavioural and subjective withdrawal effects during periods of abstinence. Consequently, there has been near-complete absence of adequate methodological controls against confounding due to reversal of withdrawal effects when caffeine is experimentally administered. The findings of what has been a substantial research effort to elucidate the effects of caffeine on sleep and wakefulness, undertaken over a period spanning decades, are ambiguous. Current shortcomings can be redressed by incorporating suitable controls in new experimental designs.

  11. Children's judgements of social withdrawal behaviours.

    Science.gov (United States)

    Watling, Dawn

    2015-06-01

    Ding et al. (Brit. J. Dev. Psychol., 2015; 33, 159-173) demonstrated that Chinese children discriminate between the three subtypes of social withdrawal: Shyness, unsociability, and social avoidance. This commentary on the Ding et al.'s paper highlights the need to further explore the following: (1) children's understanding of the implications of being shy, unsociable, or socially avoidant, including assessing these which we know are associated with outcomes for socially withdrawn children; (2) what additional subtypes might exist naturally within the Chinese culture; and (3) consider the implications of social withdrawal on children's developing social skills. © 2015 The British Psychological Society.

  12. Conducting a Withdrawal Survey.

    Science.gov (United States)

    Aldridge, Sue; Rowley, Jennifer

    2001-01-01

    A survey at Edge Hill College of Higher Education in Canada, designed to be part of the mechanism for monitoring and evaluating the quality of the student experience, revealed that key factors influencing withdrawal were: course not as expected, traveling difficulties, institution not as expected, domestic difficulties, and financial difficulties.…

  13. Proceedings of the National Conference on Climate Change and Water Resources Management (1st) Held in Albuquerque, New Mexico on November 4-7, 1991

    Science.gov (United States)

    1993-12-01

    of Albuquerque, New Mexico (pop. 500,000), and El Paso, Texas- Ciudad Juarez, Chihuahua (pop. 1 million), as well as in four sister cities near the... Ciudad Juarez area. The latter twin cities currently withdraw groundwater at the highest rate anywhere in the lower Rio Grande basin (Eaton and Anderson...kcal m 2day-1), H,. is net solar (short wave) radiation, H, is atmospheric long-wave radiation, H, is conductive loss ( sensible heat), H. is

  14. Time-dependent negative reinforcement of ethanol intake by alleviation of acute withdrawal.

    Science.gov (United States)

    Cunningham, Christopher L; Fidler, Tara L; Murphy, Kevin V; Mulgrew, Jennifer A; Smitasin, Phoebe J

    2013-02-01

    Drinking to alleviate the symptoms of acute withdrawal is included in diagnostic criteria for alcoholism, but the contribution of acute withdrawal relief to high alcohol intake has been difficult to model in animals. Ethanol dependence was induced by passive intragastric ethanol infusions in C57BL/6J (B6) and DBA/2J (D2) mice; nondependent control animals received water infusions. Mice were then allowed to self-administer ethanol or water intragastrically. The time course of acute withdrawal was similar to that produced by chronic ethanol vapor exposure in mice, reaching a peak at 7 to 9 hours and returning to baseline within 24 hours; withdrawal severity was greater in D2 than in B6 mice (experiment 1). Postwithdrawal delays in initial ethanol access (1, 3, or 5 days) reduced the enhancement in later ethanol intake normally seen in D2 (but not B6) mice allowed to self-infuse ethanol during acute withdrawal (experiment 2). The postwithdrawal enhancement of ethanol intake persisted over a 5-day abstinence period in D2 mice (experiment 3). D2 mice allowed to drink ethanol during acute withdrawal drank more ethanol and self-infused more ethanol than nondependent mice (experiment 4). Alcohol access during acute withdrawal increased later alcohol intake in a time-dependent manner, an effect that may be related to a genetic difference in sensitivity to acute withdrawal. This promising model of negative reinforcement encourages additional research on the mechanisms underlying acute withdrawal relief and its role in determining risk for alcoholism. Copyright © 2013 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.

  15. Acute pregabalin withdrawal: a case report and review of the literature

    Directory of Open Access Journals (Sweden)

    Barrett JA

    2015-05-01

    Full Text Available Objective: Pregabalin is a commonly prescribed GABA analog most commonly used for the treatment of neuralgia. Recently, case reports on pregabalin have been published describing episodes that may be associated with withdrawal-like symptoms after extended or aggressive therapy. This report describes a case in which long term exposure of high dose pregabalin may have resulted in acute withdrawal, and outlines the subsequent medical management of these symptoms. Case Summary: A 61-year-old male presenting with severe agitation presumed to be withdrawal from long term and high dose exposure to pregabalin. Medical management included the use of haloperidol, diphenhydramine, lorazepam and the addition of clonidine over the course of several days for the pharmacological management of withdrawal symptoms. Discussion: Although case reports are available to guide clinicians in the recognition of acute pregabalin withdrawal, definitive evidence on how best to treat these patients remains severely limited. With an increase in the prescribing practices of pregabalin, insight into the acute management by fellow clinicians is further needed. Conclusion: Caution must be practiced when prescribing and educating patients on the use of pregabalin to prevent associated withdrawal-like symptoms. In addition, documentation by the medical community on methods utilized to treat pregabalin withdrawal syndromes remains crucial for the advancement of patient care. Benzodiazepines and clonidine are the current therapies that have been documented as potentially effective treatment modalities at this time.

  16. Impacts of crop insurance on water withdrawals for irrigation

    Science.gov (United States)

    Deryugina, Tatyana; Konar, Megan

    2017-12-01

    Agricultural production remains particularly vulnerable to weather fluctuations and extreme events, such as droughts, floods, and heat waves. Crop insurance is a risk management tool developed to mitigate some of this weather risk and protect farmer income in times of poor production. However, crop insurance may have unintended consequences for water resources sustainability, as the vast majority of freshwater withdrawals go to agriculture. The causal impact of crop insurance on water use in agriculture remains poorly understood. Here, we determine the empirical relationship between crop insurance and irrigation water withdrawals in the United States. Importantly, we use an instrumental variables approach to establish causality. Our methodology exploits a major policy change in the crop insurance system - the 1994 Federal Crop Insurance Reform Act - which imposed crop insurance requirements on farmers. We find that a 1% increase in insured crop acreage leads to a 0.223% increase in irrigation withdrawals, with most coming from groundwater aquifers. We identify farmers growing more groundwater-fed cotton as an important mechanism contributing to increased withdrawals. A 1% increase in insured crop acreage leads to a 0.624% increase in cotton acreage, or 95,602 acres. These results demonstrate that crop insurance causally leads to more irrigation withdrawals. More broadly, this work underscores the importance of determining causality in the water-food nexus as we endeavor to achieve global food security and water resources sustainability.

  17. Gut microbiota modulates alcohol withdrawal-induced anxiety in mice.

    Science.gov (United States)

    Xiao, Hui-Wen; Ge, Chang; Feng, Guo-Xing; Li, Yuan; Luo, Dan; Dong, Jia-Li; Li, Hang; Wang, Haichao; Cui, Ming; Fan, Sai-Jun

    2018-05-01

    Excessive alcohol consumption remains a major public health problem that affects millions of people worldwide. Accumulative experimental evidence has suggested an important involvement of gut microbiota in the modulation of host's immunological and neurological functions. However, it is previously unknown whether enteric microbiota is implicated in the formation of alcohol withdrawal-induced anxiety. Using a murine model of chronic alcoholism and withdrawal, we examined the impact of alcohol consumption on the possible alterations of gut microbiota as well as alcohol withdrawal-induced anxiety and behavior changes. The 16S rRNA sequencing revealed that alcohol consumption did not alter the abundance of bacteria, but markedly changed the composition of gut microbiota. Moreover, the transplantation of enteric microbes from alcohol-fed mice to normal healthy controls remarkably shaped the composition of gut bacteria, and elicited behavioral signs of alcohol withdrawal-induced anxiety. Using quantitative real-time polymerase chain reaction, we further confirmed that the expression of genes implicated in alcohol addiction, BDNF, CRHR1 and OPRM1, was also altered by transplantation of gut microbes from alcohol-exposed donors. Collectively, our findings suggested a possibility that the alterations of gut microbiota composition might contribute to the development of alcohol withdrawal-induced anxiety, and reveal potentially new etiologies for treating alcohol addiction. Copyright © 2018 The Author(s). Published by Elsevier B.V. All rights reserved.

  18. A rare case of complicated opioid withdrawal in delirium without convulsions

    OpenAIRE

    B Neeraj Raj; N Manamohan; Divya Hegde; Chandrashekar B Huded; Johnson Pradeep

    2017-01-01

    Opioids are one of the commonly abused substances in India. Opioid withdrawal symptoms classically include severe muscle cramps, bone aches, autonomic symptoms, anxiety, restlessness, insomnia, and temperature dysregulation. However, reports of cases with delirium during withdrawal are few. A 25-year-old male with severe opioid withdrawal symptoms developed delirium. Investigations were normal. There were no comorbidities, no significant past history and family history. Patient treated for op...

  19. An alcohol withdrawal test battery measuring multiple behavioral symptoms in mice.

    Science.gov (United States)

    Metten, Pamela; Schlumbohm, Jason P; Huang, Lawrence C; Greenberg, Gian D; Hack, Wyatt R; Spence, Stephanie E; Crabbe, John C

    2018-05-01

    Despite acceptance that risk for alcohol-use disorder (AUD) has a large genetic component, the identification of genes underlying various components of risk for AUD has been hampered in humans, in part by the heterogeneity of expression of the phenotype. One aspect of AUD is physical dependence. Alcohol withdrawal is a serious consequence of alcohol dependence with multiple symptoms, many of which are seen in multiple species, and can be experienced over a wide-ranging time course. In the present three studies, we developed a battery of withdrawal tests in mice, examining behavioral symptoms from multiple domains that could be measured over time. To permit eventual use of the battery in different strains of mice, we used male and female mice of a genetically heterogeneous stock developed from intercrossing eight inbred strains. Withdrawal symptoms were assessed using commonly used tests after administration of ethanol in vapor for 72 continuous hours. We found significant effects of ethanol withdrawal versus air-breathing controls on nearly all symptoms, spanning 4 days following ethanol vapor inhalation. Withdrawal produced hypothermia, greater neurohyperexcitability (seizures and tremor), anxiety-like behaviors using an apparatus (such as reduced transitions between light and dark compartments), anhedonia (reduced sucrose preference), Straub tail, backward walking, and reductions in activity; however, there were no changes in thermal pain sensitivity, hyper-reactivity to handling, or anxiety-like emergence behaviors in other apparatus. Using these data, we constructed a refined battery of withdrawal tests. Individual differences in severity of withdrawal among different tests were weakly correlated at best. This battery should be useful for identifying genetic influences on particular withdrawal behaviors, which should reflect the influences of different constellations of genes. Published by Elsevier Inc.

  20. 27 CFR 19.532 - Withdrawals of spirits for use in wine production.

    Science.gov (United States)

    2010-04-01

    ... use in wine production. 19.532 Section 19.532 Alcohol, Tobacco Products and Firearms ALCOHOL AND... Withdrawals Withdrawal of Spirits Without Payment of Tax § 19.532 Withdrawals of spirits for use in wine production. Wine spirits may be withdrawn to a bonded wine cellar without payment of tax for use in wine...

  1. Waste Isolation Pilot Plant Biennial Environmental Compliance Report

    Energy Technology Data Exchange (ETDEWEB)

    Washington Regulatory and Environmental Services (WRES)

    2004-10-25

    This Biennial Environmental Compliance Report (BECR) documents environmental regulatory compliance at the Waste Isolation Pilot Plant (WIPP), a facility designed and authorized for the safe disposal of transuranic (TRU) radioactive waste, for the reporting period of April 1, 2002, to March 31, 2004. As required by the WIPP Land Withdrawal Act (LWA) (Public Law [Pub. L.] 102-579, as amended by Pub. L. 104-201), the BECR documents U.S. Department of Energy (DOE) compliance with applicable environmental protection laws and regulations implemented by agencies of the federal government and the state of New Mexico.

  2. Waste Isolation Pilot Plant Biennial Environmental Compliance Report

    International Nuclear Information System (INIS)

    2004-01-01

    This Biennial Environmental Compliance Report (BECR) documents environmental regulatory compliance at the Waste Isolation Pilot Plant (WIPP), a facility designed and authorized for the safe disposal of transuranic (TRU) radioactive waste, for the reporting period of April 1, 2002, to March 31, 2004. As required by the WIPP Land Withdrawal Act (LWA) (Public Law [Pub. L.] 102-579, as amended by Pub. L. 104-201), the BECR documents U.S. Department of Energy (DOE) compliance with applicable environmental protection laws and regulations implemented by agencies of the federal government and the state of New Mexico.

  3. Evolution of Metabolic Abnormalities in Alcoholic Patients during Withdrawal

    Directory of Open Access Journals (Sweden)

    X. Vandemergel

    2015-01-01

    Full Text Available Chronic alcohol intoxication is accompanied by metabolic abnormalities. Evolution during the early withdrawal period has been poorly investigated. The aim of this study was to determine the evolution of metabolic parameters during alcohol withdrawal. Patients and Methods. Thirty-three patients admitted in our department for alcohol withdrawal were prospectively included. Results. Baseline hypophosphatemia was found in 24% of cases. FEPO4 was reduced from 14.2 ± 9% at baseline to 7.3 ± 4.2% at day 3 (Pnl, respectively. No correlation was found between the sodium and CPK levels (P=0.75 nor between the CPK level and the amount of alcohol ingested (rs = 0.084, P=0.097. Baseline urate level was elevated and returned to normal after three days. Baseline magnesium concentration was normal and stable over time. Conclusion. Chronic alcohol intoxication was accompanied by phosphaturia, rapidly reversible after alcohol withdrawal and inversely correlated with albuminemia, slight hyponatremia, low levels of 25 hydroxy vitamin D, elevated CPK level in about 30% of women, and hyperuricemia with rapid normalization.

  4. It's self defense: how perceived discrimination promotes employee withdrawal.

    Science.gov (United States)

    Volpone, Sabrina D; Avery, Derek R

    2013-10-01

    Integrating theory on stress, stigma, and coping, the present study sheds light on how employees react to perceived discrimination (PD) in the workplace. Using three national samples, we found that PD based on race, sex, age, family obligation, and sexual orientation related to physical withdrawal (i.e., lateness, absenteeism,and intent to quit) indirectly through psychological withdrawal (i.e., burnout and engagement) such that PD corresponded in less engagement and more burnout, which related to increased lateness, absenteeism, and intent to quit [corrected].Further, these indirect relationships were moderated by employees' coping mechanisms with those who were more apt to change the situation or to avoid the stressor exhibiting weaker relationships between PD and psychological withdrawal. Though each of these studies is cross-sectional in nature and therefore cannot provide strong evidence of causal ordering of the variables in our model, the replication and extension of results over three databases and multiple forms of discrimination, coping, psychological, and physical withdrawal demonstrates that understanding the relationships explored in these studies can aid researchers and practitioners in enhancing employee quality of life and productivity.

  5. Worldwide withdrawal of medicinal products because of adverse drug reactions: a systematic review and analysis.

    Science.gov (United States)

    Onakpoya, Igho J; Heneghan, Carl J; Aronson, Jeffrey K

    2016-07-01

    We have systematically identified medicinal products withdrawn worldwide because of adverse drug reactions, assessed the level of evidence used for making the withdrawal decisions, and explored the patterns of withdrawals over time. We searched PubMed, the WHO database of withdrawn products, and selected texts. We included products that were withdrawn after launch from 1950 onwards, excluding non-human and over-the-counter medicines. We assessed the levels of evidence on which withdrawals were based using the Oxford Center for Evidence Based Medicine Levels of Evidence. Of 353 medicinal products withdrawn from any country, only 40 were withdrawn worldwide. Anecdotal reports were cited as evidence for withdrawal in 30 (75%) and deaths occurred in 27 (68%). Hepatic, cardiac, and nervous system toxicity accounted for over 60% of withdrawals. In 28 cases, the first withdrawal was initiated by the manufacturer. The median interval between the first report of an adverse drug reaction that led to withdrawal and the first withdrawal was 1 year (range 0-43 years). Worldwide withdrawals occurred within 1 year after the first withdrawal in any country. In conclusion, the time it takes for drugs to be withdrawn worldwide after reports of adverse drug reactions has shortened over time. However, there are inconsistencies in current withdrawal procedures when adverse drug reactions are suspected. A uniform method for establishing worldwide withdrawal of approved medicinal products when adverse drug reactions are suspected should be developed, to facilitate global withdrawals. Rapid synthesis of the evidence on harms should be a priority when serious adverse reactions are suspected.

  6. New Mexico's energy resources '80. Annual report of Bureau of Geology in the mining and minerals Division of New Mexico Energy and Minerals Department

    International Nuclear Information System (INIS)

    Arnold, E.C.; Hill, J.M.

    1981-01-01

    Because of a steady depletion of reserves and the failure to make new discoveries in recent years, production of crude oil in New Mexico declined in 1979 with a production of 74.7 million bbls (barrels), which was 3.4 million bbls or 4.6 percent less than 1978 production. Although condensate production increased slightly over the previous year, total crude and condensate production continued to decline. Natural-gas production increased in 1979 by 3,565,351 thousand cu ft or 4 percent from the previous year, with an increase in production occurring in northwest New Mexico. Drilling continued to increase as the total number of well completions in New Mexico in 1979 was the highest in the past 9 yrs. Primary and secondary crude oil reserves were calculated for 50 major pools in southeast New Mexico and for selected oil and gas wells in northwest New Mexico. Coal production increased 1.8 million tons in 1979 or 14 percent over 1978 production, and a more extensive expansion will depend partly on factors such as the availability of rail transportation to new areas. The development of synthetic fuel technology may have a substantial impact on longer term coal production. Production of U 3 O 8 declined 13 percent from 1978 with 7420 tons U 3 O 8 reported as production in 1979. A depressed uranium market and other economic factors contributed to the decline in production. New Mexico, however, continues to lead the nation in production and uranium reserves. Researchers are continuing to explore geothermal energy applications and to characterize geothermal systems in the state, and the US Bureau of Land Management has issued 126 geothermal leases that remain active. Recent geothermal exploration activity has been detailed for 14 companies

  7. Environmental assessment for Sandia National Laboratories/New Mexico offsite transportation of low-level radioactive waste

    International Nuclear Information System (INIS)

    1996-09-01

    Sandia National Laboratories, New Mexico (SNL/NM) is managed and operated by Sandia Corporation, a Lockheed Martin Company. SNL/NM is located on land owned by the U.S. Department of Energy (DOE) within the boundaries of the Kirtland Air Force Base (KAFB) in Albuquerque, New Mexico. The major responsibilities of SNL/NM are the support of national security and energy projects. Low-level radioactive waste (LLW) is generated by some of the activities performed at SNL/NM in support of the DOE. This report describes potential environmental effects of the shipments of low-level radioactive wastes to other sites

  8. Interpreting compositional zonation of the Zaragoza ignimbrite from Los Humeros caldera, Central Mexico

    International Nuclear Information System (INIS)

    Carrasco-Nunez, Gerardo; McCurry, Michael; Branney, Michael J

    2008-01-01

    Compositional zonation in ignimbrites is relatively common, and is often inferred to record gradual withdrawal by an eruption of a density-stratified magma chamber (with silicic magma towards the top and more dense, mafic magma at the bottom). We show that this model does not match observations at the ca. 0.1 Ma Zaragoza ignimbrite from Los Humeros caldera in central Mexico. Detailed petrologic studies reveal a more complex scenario: the ignimbrite exhibits a 'double' vertical zonation based on the compositions of pumice lapilli. We present evidence for mingling and limited mixing occurred during or immediately before the caldera-forming eruption. One possibility to explain the observations is that the ignimbrite eruption occurred in response to intrusion of a hybridized andesitic magma into a rhyodacitic magma chamber.

  9. Texas-Mexico multimodal transportation: developments in Mexico

    Science.gov (United States)

    Boske, Leigh B.

    1994-03-01

    This presentation highlights the results of a recently completed study that examines the Texas- Mexico multimodal transport system already in place, current plans for improvements or expansion, and opportunities and constraints faced by each transport mode -- motor carriage, rail, maritime, and air. Particular emphasis is given to findings regarding transportation developments in Mexico. The study concludes that in Mexico, all modes are working at establishing new services and strategic alliances, intermodal arrangements are on the rise, and private-sector participation in infrastructure improvements is growing daily at Mexican seaports and airports as well as within that nation's highway and rail systems. This presentation looks at developments that concern privatization, deregulation, infrastructure improvements, financing arrangements, and new services in Mexico.

  10. Object relations, reality testing, and social withdrawal in schizophrenia and bipolar disorder.

    Science.gov (United States)

    Hansen, Charlotte Fredslund; Torgalsbøen, Anne-Kari; Røssberg, Jan Ivar; Romm, Kristin Lie; Andreassen, Ole Andreas; Bell, Morris D; Melle, Ingrid

    2013-03-01

    In this study, we investigated the relationships between observed social withdrawal (Positive and Negative Syndrome Scale [PANSS] Passive Social Withdrawal and PANSS Active Social Avoidance), subjectively experienced social withdrawal (Social Functioning Scale [SFS] Withdrawal and SFS Interpersonal Behavior), and their associations to the underlying psychological patterns of Object Relations and Reality Testing. Patients with schizophrenia (n = 55) and bipolar disorder (n = 51) from the ongoing Thematically Organized Psychosis project, Oslo University Hospital, Norway, were evaluated using the Bell Object Relations and Reality Testing Inventory, the PANSS, and the SFS. Object relations and reality testing subscales related differentially to PANSS Passive Social Withdrawal and PANSS Active Social Avoidance. These two measures, together with the level of alienation, explained a significant amount of variance in self-experienced social dysfunction. Findings reveal the multidimensional nature of social dysfunction in severe mental disorders.

  11. September 1985 Mexico City, Mexico Images

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The magnitude 8.1 earthquake occurred off the Pacific coast of Mexico. The damage was concentrated in a 25 square km area of Mexico City, 350 km from the epicenter....

  12. Residents' perceptions about surrogate decision makers' financial conflicts of interest in ventilator withdrawal.

    Science.gov (United States)

    Wastila, Lisa J; Farber, Neil J

    2014-05-01

    There have been no studies to date that examine physicians' decisions to withdraw life-sustaining treatment for patients based on their surrogates' financial gain. The authors' objective was to ascertain physician attitudes about withdrawing life-sustaining treatment when financial considerations are involved. A survey was developed and pretested containing eight scenarios in which a terminally ill patient's spouse had a decision to make regarding withdrawal of the ventilator, which was deemed medically futile. Nested variables included agreement or disagreement between the spouse and patient, decision to withdraw or continue the ventilator, and financial gain or no financial gain for the spouse. The authors surveyed all internal medicine residents at the University of California, San Diego in the autumn of 2011 and winter of 2012. The responses on each of the three variables for which respondents were likely to withdraw the ventilator were analyzed via student's t-tests. Residents were more likely to withdraw the ventilator when requested to do so than when it was requested to be continued. They were also more likely to withdraw the ventilator when there was agreement in the decision between the spouse and the patient. Residents were more likely to withdraw the ventilator when the spouse would not benefit financially. Internal medicine residents make some decisions about whether to withdraw life-sustaining treatment based on financial considerations. There needs to be ongoing communication with residents about end-of-life decisions where conflicts may exist between the surrogate decision makers and patients or physicians.

  13. 8 CFR 246.4 - Immigration judge's authority; withdrawal and substitution.

    Science.gov (United States)

    2010-01-01

    ... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Immigration judge's authority; withdrawal... IMMIGRATION REGULATIONS RESCISSION OF ADJUSTMENT OF STATUS § 246.4 Immigration judge's authority; withdrawal and substitution. In any proceeding conducted under this part, the immigration judge shall have...

  14. 20 CFR 416.360 - Cancellation of a request to withdraw.

    Science.gov (United States)

    2010-04-01

    ....360 Section 416.360 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Filing of Applications Withdrawal of Application § 416.360... received after we have approved the withdrawal, the cancellation request is filed no later than 60 days...

  15. Trajectories of Social Withdrawal from Middle Childhood to Early Adolescence

    Science.gov (United States)

    Oh, Wonjung; Rubin, Kenneth H.; Bowker, Julie C.; Booth-LaForce, Cathryn; Rose-Krasnor, Linda; Laursen, Brett

    2008-01-01

    Heterogeneity and individual differences in the developmental course of social withdrawal were examined longitudinally in a community sample (N = 392). General Growth Mixture Modeling (GGMM) was used to identify distinct pathways of social withdrawal, differentiate valid subgroup trajectories, and examine factors that predicted change in…

  16. On the historical account of disastrous landslides in Mexico: the challenge of risk management and disaster prevention

    Science.gov (United States)

    Alcántara-Ayala, I.

    2008-01-01

    Landslides disasters in Mexico caused more than 3500 deaths between 1935 and 2006. Such disasters have been mainly associated to intense precipitation events derived from hurricanes, tropical storms and their interactions with cold fronts, although earthquake triggered landslides have also occurred to a lesser extent. The impact of landsliding in Mexico is basically determined by the geomorphic features of mountain ranges and dissected plateaus inhabited by vulnerable communities. The present contribution provides a comprehensive temporal assessment of historical landslide disasters in Mexico. Moreover, it aims at exploring the future directions of risk management and disaster prevention, in order to reduce the impact of landslides on populations as a result of climatic change, urban sprawl, land use change and social vulnerability.

  17. Arizona/New Mexico Mountains Ecoregion: Chapter 10 in Status and trends of land change in the Western United States--1973 to 2000

    Science.gov (United States)

    Ruhlman, Jana; Gass, Leila; Middleton, Barry

    2012-01-01

    As the name suggests, the Arizona/New Mexico Mountains Ecoregion includes much of the mountainous regions of these two states, plus a very small part in the Guadalupe Mountains of northwestern Texas. Several isolated areas of higher terrain in Arizona and New Mexico are also included in the ecoregion, which occupies approximately 108,432 km2 (41,866 mi2) (Omernik, 1987; U.S. Environmental Protection Agency, 1997). The ecoregion is bounded on the south by the Sonoran Basin and Range, Madrean Archipelago, and Chihuahuan Deserts Ecoregions; to the north, the ecoregion is both bounded and surrounded by the Arizona/New Mexico Plateau Ecoregion (fig. 1). The ecoregion encompasses the largest contiguous ponderosa pine (Pinus ponderosa) forest in the United States (Strom and Fulé, 2007), which stretches from Williams, Arizona, along the Mogollon Rim, Arizona, into southwestern New Mexico, north and west of Silver City, New Mexico.

  18. ENVIRONMENTAL ASSESSMENT FOR THE PROPOSED WITHDRAWAL OF PUBLIC LANDS WITHIN AND SURROUNDING THE CALIENTE RAIL CORRIDOR, NEVADA

    International Nuclear Information System (INIS)

    DOE

    2005-01-01

    The purpose for agency action is to preclude surface entry and the location of new mining claims, subject to valid existing rights, within and surrounding the Caliente rail corridor as described in the Yucca Mountain FEIS (DOE 2002). This protective measure is needed to enhance the safe, efficient, and uninterrupted evaluation of land areas for potential rail alignments within the Caliente rail corridor. The evaluation will assist the DOE in determining, through the Rail Alignment environmental impact statement (EIS) process, whether to construct a branch rail line, and to provide support to the BLM in deciding whether or not to reserve a ROW for the rail line under the Federal Land Policy and Management Act (FLPMA). The BLM participated as a cooperating agency in preparing this EA because it is the responsible land manager and BLM staff could contribute resource specific expertise

  19. ENVIRONMENTAL ASSESSMENT FOR THE PROPOSED WITHDRAWAL OF PUBLIC LANDS WITHIN AND SURROUNDING THE CALIENTE RAIL CORRIDOR, NEVADA

    Energy Technology Data Exchange (ETDEWEB)

    DOE

    2005-12-01

    The purpose for agency action is to preclude surface entry and the location of new mining claims, subject to valid existing rights, within and surrounding the Caliente rail corridor as described in the Yucca Mountain FEIS (DOE 2002). This protective measure is needed to enhance the safe, efficient, and uninterrupted evaluation of land areas for potential rail alignments within the Caliente rail corridor. The evaluation will assist the DOE in determining, through the Rail Alignment environmental impact statement (EIS) process, whether to construct a branch rail line, and to provide support to the BLM in deciding whether or not to reserve a ROW for the rail line under the Federal Land Policy and Management Act (FLPMA). The BLM participated as a cooperating agency in preparing this EA because it is the responsible land manager and BLM staff could contribute resource specific expertise.

  20. 19 CFR 181.53 - Collection and waiver or reduction of duty under duty-deferral programs.

    Science.gov (United States)

    2010-04-01

    ... Canada or Mexico as reflected on the applicable Canadian or Mexican entry document (see § 181.47(c) (1... or Mexico or for entry into a Canadian or Mexican duty-deferral program. Such measures govern... the case of a withdrawal of the goods from a warehouse, the person who has the right to withdraw the...

  1. A Water-Withdrawal Input-Output Model of the Indian Economy.

    Science.gov (United States)

    Bogra, Shelly; Bakshi, Bhavik R; Mathur, Ritu

    2016-02-02

    Managing freshwater allocation for a highly populated and growing economy like India can benefit from knowledge about the effect of economic activities. This study transforms the 2003-2004 economic input-output (IO) table of India into a water withdrawal input-output model to quantify direct and indirect flows. This unique model is based on a comprehensive database compiled from diverse public sources, and estimates direct and indirect water withdrawal of all economic sectors. It distinguishes between green (rainfall), blue (surface and ground), and scarce groundwater. Results indicate that the total direct water withdrawal is nearly 3052 billion cubic meter (BCM) and 96% of this is used in agriculture sectors with the contribution of direct green water being about 1145 BCM, excluding forestry. Apart from 727 BCM direct blue water withdrawal for agricultural, other significant users include "Electricity" with 64 BCM, "Water supply" with 44 BCM and other industrial sectors with nearly 14 BCM. "Construction", "miscellaneous food products"; "Hotels and restaurants"; "Paper, paper products, and newsprint" are other significant indirect withdrawers. The net virtual water import is found to be insignificant compared to direct water used in agriculture nationally, while scarce ground water associated with crops is largely contributed by northern states.

  2. Consequences of dextropropoxyphene market withdrawal in elderly patients with chronic pain.

    Science.gov (United States)

    Becquemont, Laurent; Delespierre, Tiba; Bauduceau, Bernard; Benattar-Zibi, Linda; Berrut, Gilles; Corruble, Emmanuelle; Danchin, Nicolas; Derumeaux, Geneviève; Doucet, Jean; Falissard, Bruno; Forette, Francoise; Hanon, Olivier; Pasquier, Florence; Pinget, Michel; Ourabah, Rissane; Bucher, Sophie; Lazkani, Aida; Piedvache, Celine; Bertin, Philippe

    2014-10-01

    Describe the consequences of dextropropoxyphene (DXP) market withdrawal on analgesic prescriptions and on the quality of therapeutic management of chronic pain. From a cohort of non-institutionalised elderly patients with chronic pain recruited by general practitioners, we selected patients who were treated with DXP daily for at least 6 months just prior to DXP market withdrawal and who had an evaluation of pain and its impact on daily activities before and after DXP withdrawal. One hundred three patients took DXP daily for chronic pain. Immediately after DXP market withdrawal, 42 (40.8%), 55 (53.4%) and 3 (2.9%) patients were treated with step 1, 2 and 3 analgesics, respectively, and 3 patients (2.9%) were no longer receiving any analgesic medication. Among the 55 patients who continued on step 2 analgesics, 37 were treated with tramadol, 14 with codeine and 9 with opium. Pain intensity and the impact of pain on daily activities remained stable. DXP market withdrawal had no consequences on the intensity or impact of chronic pain in elderly patients.

  3. Flumazenil in treatment benzodiazepine withdrawal syndrome: Case report

    Directory of Open Access Journals (Sweden)

    Ramah Aleksandar J.

    2015-01-01

    Full Text Available Background: Today in the world and in Serbia is growing number of people who are addicted to benzodiazepine. A particular problem is the process of detoxification and treatment of benzodiazepine withdrawal syndrome due to a recurrence of symptoms of anxiety disorder, availability of benzodiazepines, falling motivation. Standard procedures have often proved unsuccessful and the last decade, and the search for new protocols, including the flumazenil, benzodiazepine receptor antagonist, is actualized. Case report: The patient aged 48 years was admitted to the specialist psychiatric clinic, for treatment of benzodiazepine addiction. Anxiety disorder was diagnosed since adolescence perennial addiction on benzodiazepines and the initial withdrawal syndrome. Former motivated topical treatments for detoxification were unsuccessful. The presence of dual diagnosis, persistence of both disorders in perennial cycle, treatment resistance and actual motivation contributed to the decision to opt rapid detoxification from benzodiazepines by flumazenil application protocol, for hospital treatment by adjuvant therapy with lamotrigine. After discharge from hospital in stable condition it was with no signs of withdrawal syndrome and a rebound of anxiety symptoms. Lamotrigine medication continued including CBT, held during the one-year abstinence monitoring, with sufficient social functionality. Discussion: The efficacy and safety of flumazenil in the treatment of benzodiazepine withdrawal syndrome was investigated in numerous clinical trials, and the mechanism of action is complex, from the benzodiazepine antagonist to inverse agonist in certain circumstances, as well as 'up-regulation' receptors, which together leads to a reduction in symptoms of abstinence syndrome and anxiety in the longer term after treatment, thereby acting favorably to the adherence and remission. Conclusions: Flumazenil protocol is an efficient method in the treatment of the benzodiazepine

  4. Navigating challenges and opportunities of land degradation and sustainable livelihood development in dryland social-ecological systems: a case study from Mexico.

    Science.gov (United States)

    Huber-Sannwald, Elisabeth; Palacios, Mónica Ribeiro; Moreno, José Tulio Arredondo; Braasch, Marco; Peña, Ruth Magnolia Martínez; Verduzco, Javier García de Alba; Santos, Karina Monzalvo

    2012-11-19

    Drylands are one of the most diverse yet highly vulnerable social-ecological systems on Earth. Water scarcity has contributed to high levels of heterogeneity, variability and unpredictability, which together have shaped the long coadaptative process of coupling humans and nature. Land degradation and desertification in drylands are some of the largest and most far-reaching global environmental and social change problems, and thus are a daunting challenge for science and society. In this study, we merged the Drylands Development Paradigm, Holling's adaptive cycle metaphor and resilience theory to assess the challenges and opportunities for livelihood development in the Amapola dryland social-ecological system (DSES), a small isolated village in the semi-arid region of Mexico. After 450 years of local social-ecological evolution, external drivers (neoliberal policies, change in land reform legislation) have become the most dominant force in livelihood development, at the cost of loss of natural and cultural capital and an increasingly dysfunctional landscape. Local DSESs have become increasingly coupled to dynamic larger-scale drivers. Hence, cross-scale connectedness feeds back on and transforms local self-sustaining subsistence farming conditions, causing loss of livelihood resilience and diversification in a globally changing world. Effective efforts to combat desertification and improve livelihood security in DSESs need to consider their cyclical rhythms. Hence, we advocate novel dryland stewardship strategies, which foster adaptive capacity, and continuous evaluation and social learning at all levels. Finally, we call for an effective, flexible and viable policy framework that enhances local biotic and cultural diversity of drylands to transform global drylands into a resilient biome in the context of global environmental and social change.

  5. Navigating challenges and opportunities of land degradation and sustainable livelihood development in dryland social–ecological systems: a case study from Mexico

    Science.gov (United States)

    Huber-Sannwald, Elisabeth; Ribeiro Palacios, Mónica; Arredondo Moreno, José Tulio; Braasch, Marco; Martínez Peña, Ruth Magnolia; de Alba Verduzco, Javier García; Monzalvo Santos, Karina

    2012-01-01

    Drylands are one of the most diverse yet highly vulnerable social–ecological systems on Earth. Water scarcity has contributed to high levels of heterogeneity, variability and unpredictability, which together have shaped the long coadaptative process of coupling humans and nature. Land degradation and desertification in drylands are some of the largest and most far-reaching global environmental and social change problems, and thus are a daunting challenge for science and society. In this study, we merged the Drylands Development Paradigm, Holling's adaptive cycle metaphor and resilience theory to assess the challenges and opportunities for livelihood development in the Amapola dryland social–ecological system (DSES), a small isolated village in the semi-arid region of Mexico. After 450 years of local social–ecological evolution, external drivers (neoliberal policies, change in land reform legislation) have become the most dominant force in livelihood development, at the cost of loss of natural and cultural capital and an increasingly dysfunctional landscape. Local DSESs have become increasingly coupled to dynamic larger-scale drivers. Hence, cross-scale connectedness feeds back on and transforms local self-sustaining subsistence farming conditions, causing loss of livelihood resilience and diversification in a globally changing world. Effective efforts to combat desertification and improve livelihood security in DSESs need to consider their cyclical rhythms. Hence, we advocate novel dryland stewardship strategies, which foster adaptive capacity, and continuous evaluation and social learning at all levels. Finally, we call for an effective, flexible and viable policy framework that enhances local biotic and cultural diversity of drylands to transform global drylands into a resilient biome in the context of global environmental and social change. PMID:23045713

  6. Deadly pressure pneumothorax after withdrawal of misplaced feeding tube

    DEFF Research Database (Denmark)

    Andresen, Erik Nygaard; Frydland, Martin; Usinger, Lotte

    2016-01-01

    BACKGROUND: Many patients have a nasogastric feeding tube inserted during admission; however, misplacement is not uncommon. In this case report we present, to the best of our knowledge, the first documented fatality from pressure pneumothorax following nasogastric tube withdrawal. CASE PRESENTATION......, but our patient died less than an hour after withdrawal. The autopsy report stated that cause of death was tension pneumothorax, which developed following withdrawal of the misplaced feeding tube. CONCLUSIONS: The indications for insertion of nasogastric feeding tubes are many and the procedure...... is considered harmless; however, if the tube is misplaced there is good reason to be cautious on removal as this can unmask puncture of the pleura eliciting pneumothorax and, as this case report shows, result in an ultimately deadly tension pneumothorax....

  7. Infants in Drug Withdrawal: A National Description of Nurse Workload, Infant Acuity, and Parental Needs.

    Science.gov (United States)

    Smith, Jessica G; Rogowski, Jeannette A; Schoenauer, Kathryn M; Lake, Eileen T

    Infants in drug withdrawal have complex physiological and behavioral states, requiring intensive nursing care. The study objectives were to describe acuity, parental needs, and nurse workload of infants in drug withdrawal compared with other infants. The design was cross-sectional and involved secondary nurse survey data from 6045 staff nurses from a national sample of 104 neonatal intensive care units. Nurses reported the care of 15 233 infants, 361 (2.4%) of whom were in drug withdrawal. Three-fourths of hospitals had at least 1 infant in drug withdrawal. In these hospitals, the mean number of infants in drug withdrawal was 4.7. Infant acuity was significantly higher among infants in drug withdrawal. Parents of infants in drug withdrawal required significantly more care to address complex social situations (51% vs 12%). The number of infants assigned to nurses with at least 1 infant in withdrawal (mean = 2.69) was significantly higher than typical (mean = 2.51). Given infant acuity and parental needs, policies legislating patient-to-nurse ratios should permit professional discretion on the number of patients to assign nurses caring for infants in drug withdrawal. Managers and charge nurses should consider the demands of caring for infants in drug withdrawal in assignment decisions and provide support and education.

  8. Estimated water withdrawals and return flows in Vermont in 2005 and 2020

    Science.gov (United States)

    Medalie, Laura; Horn, Marilee A.

    2010-01-01

    In 2005, about 12 percent of total water withdrawals (440 million gallons per day (Mgal/d)) in Vermont were from groundwater sources (51 Mgal/d), and about 88 percent were from surface-water sources (389 Mgal/d). Of total water withdrawals, about 78 percent were used for cooling at a power plant, 9 percent were withdrawn by public suppliers, about 5 percent were withdrawn for domestic use, about 3 percent were withdrawn for use at fish hatcheries, and the remaining 5 percent were divided among commercial/industrial, irrigation, livestock, and snowmaking uses. About 49 percent of the population of Vermont was supplied with drinking water by a public supplier, and 51 percent was self supplied. Some of the Minor Civil Divisions (MCDs) that had large self-supplied populations were located near the major cities of St. Albans, Burlington, Montpelier, Barre, and Rutland, where the cities themselves were served largely by public supply, but the surrounding areas were not. Most MCDs where withdrawals by community water systems totaled more than 1 Mgal/d used predominantly surface water, and those where withdrawals by community water systems totaled 1 Mgal/d or less used predominantly groundwater. Withdrawals of groundwater greater than 1 Mgal/d were made in Middlebury, Bethel, Hartford, Springfield, and Bennington, and withdrawals of surface water greater than 2 Mgal/d were made in Grand Isle, Burlington, South Burlington, Mendon, Brattleboro, and Vernon. Increases in groundwater withdrawals greater than 0.1 Mgal/d are projected for 2020 for Fairfax, Hardwick, Middlebury, Sharon, Proctor, Springfield, and Manchester. The largest projected increases in surface-water withdrawals from 2005 to 2020 are located along the center axis of the Green Mountains in the ski-area towns of Stowe, Warren, Mendon, Killington, and Wilmington. In 2005, withdrawals were at least 1 Mgal/d greater than return flows in South Burlington, Waterford, Orange, Mendon, Woodford, and Vernon. Many of

  9. Sandia National Laboratories/New Mexico Environmental Information Document - Volume II

    Energy Technology Data Exchange (ETDEWEB)

    GUERRERO, JOSEPH V.; KUZIO, KENNETH A.; JOHNS, WILLIAM H.; BAYLISS, LINDA S.; BAILEY-WHITE, BRENDA E.

    1999-09-01

    This Sandia National Laboratories/New Mexico Environmental Information Document (EID) compiles information on the existing environment, or environmental baseline, for SNUNM. Much of the information is drawn from existing reports and databases supplemented by new research and data. The SNL/NM EID, together with the Sandia National Laboratories/New Mexico Facilities and Safety Information Document, provide a basis for assessing the environment, safety, and health aspects of operating selected facilities at SNL/NM. The environmental baseline provides a record of the existing physical, biological, and socioeconomic environment at SNL/NLM prior to being altered (beneficially or adversely) by proposed programs or projects. More specifically, the EID provides information on the following topics: Geology; Land Use; Hydrology and Water Resources; Air Quality and Meteorology; Ecology; Noise and Vibration; Cultural Resources; Visual Resources; Socioeconomic and Community Services; Transportation; Material Management; Waste Management; and Regulatory Requirements.

  10. Sandia National Laboratories/New Mexico Environmental Information Document - Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    BAYLISS, LINDA S.; GUERRERO, JOSEPH V.; JOHNS, WILLIAM H.; KUZIO, KENNETH A.; BAILEY-WHITE, BRENDA E.

    1999-09-01

    This Sandia National Laboratories/New Mexico Environmental Information Document (EID) compiles information on the existing environment, or environmental baseline, for SNUNM. Much of the information is drawn from existing reports and databases supplemented by new research and data. The SNL/NM EID, together with the Sandia National Laboratories/New Mexico Facilities and Safety Information Document, provide a basis for assessing the environment, safety, and health aspects of operating selected facilities at SNL/NM. The environmental baseline provides a record of the existing physical, biological, and socioeconomic environment at SNL/NLM prior to being altered (beneficially or adversely) by proposed programs or projects. More specifically, the EID provides information on the following topics: Geology; Land Use; Hydrology and Water Resources; Air Quality and Meteorology; Ecology; Noise and Vibration; Cultural Resources; Visual Resources; Socioeconomic and Community Services; Transportation; Material Management; Waste Management; and Regulatory Requirements.

  11. Potential harms, anonymization, and the right to withdraw consent to biobank research.

    Science.gov (United States)

    Eriksson, Stefan; Helgesson, Gert

    2005-09-01

    This paper discusses the potential harms involved in biobank research and how ethical review, informed consent, withdrawals, and anonymization of samples should be handled in the light of these harms. There is less risk involved in biobank research than in human subject research; it should therefore be treated differently. In our view, anonymization should not be an automatically permissible response to requests for withdrawal. Nor should a request for withdrawal necessarily stop research on identifiable samples. Apart from not being particularly appropriate for protecting the interests of individuals, anonymization of samples has a negative impact on research. We suggest that the current view on withdrawal from research, supported by the Declaration of Helsinki and subsequent ethical guidelines, be abandoned in the context of biobank research and be replaced by an approach inspired by the Nuremberg Code. This approach requires those wishing to withdraw their samples from research to present sufficient reason for doing so. Our interpretation of 'sufficient reason' includes all those involving genuine, deeply felt concerns that are not based on misconceptions. Still, this underlines the fact that we all share a responsibility for health research and that no one should take withdrawal from biobank research lightly.

  12. Biodiesel Obtaining from Ricinus Seed. Academical Proyect For Promoting Biofuels Use in Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Sanchez Daza, O.; Amador Ramirez, P.; Reyes Ortega, Y.; Rosas Mendoza, S.; Cervantes de la Rosa, A.; Pineda Gonzalez, A.A.

    2007-07-01

    Mexico shares a strong responsibility into Latin-America and with the rest of the world as GHG emitter. At present, this responsibility has not a minimum of response on education, economy, politics, science and technology. One of the most important contamination source in Mexico is transport which, additionally, undergoes a slow modernization process. Brazil and European Union experiences and an abundant scientific literature have shown the economical and technological feasibility for substituting fossil fuels by other renewable and clean fuels as bioethanol and biodiesel. Authors consider as fundamental objective to promote production and use of biofuels in Mexico. They are working on the investigation project which is developed in Puebla State searching to take advantage of regional row materials. Ricinus seed cultivation could stimulate regional socioeconomic conditions because of water demand is modest, currently the seed grows wildly and some land extension in the region is not active due to high emigration towards USA. Knowledge about biodiesel obtaining from diverse materials is abundant and international companies market industrial equipment and technology for producing it, nevertheless, the authors consider important to develop in Mexico adequate technology to the specific socioeconomic and natural conditions working the own raw materials. (auth)

  13. A 'symptom-triggered' approach to alcohol withdrawal management.

    Science.gov (United States)

    Murdoch, Jay; Marsden, Janet

    In acute hospital settings, alcohol withdrawal often causes significant management problems and complicates a wide variety of concurrent conditions, placing a huge burden on the NHS. A significant number of critical incidents around patients who were undergoing detoxification in a general hospital setting led to the need for a project to implement and evaluate an evidence-based approach to the management of alcohol detoxification-a project that included a pre-intervention case note audit, the implementation of an evidence-based symptom-triggered detoxification protocol, and a post-intervention case note audit. This change in practice resulted in an average reduction of almost 60% in length of hospital stay and a 66% reduction in the amount of chlordiazepoxide used in detoxification, as well as highlighting that 10% of the sample group did not display any signs of withdrawal and did not require any medication. Even with these reductions, no patient post-intervention developed any severe signs of withdrawal phenomena, such as seizures or delirium tremens. The savings to the trust (The Pennine Acute Hospital Trust) are obvious,but the development of a consistent, quality service will lead to fewer long-term negative effects for patients that can be caused by detoxification. This work is a project evaluation of a locally implemented strategy, which, it was hypothesised,would improve care by providing an individualised treatment plan for the management of alcohol withdrawal symptoms.

  14. A Case Report of Severe Delirium after Amantadine Withdrawal

    Directory of Open Access Journals (Sweden)

    Franz Marxreiter

    2017-03-01

    Full Text Available Amantadine is frequently used in addition to dopaminergic substances like dopamine agonists or L-Dopa in advanced Parkinson disease (PD. However, adverse effects like hallucinations limit its use. PD patients developing severe psychotic symptoms upon treatment with either dopaminergic substances and/or amantadine need to stop intake of any psychotropic substance. Here, we report the case of a 71-year-old PD patient without previously known cognitive impairment. He presented with drug-induced psychotic symptoms due to changes in his therapeutic regimen (increase in COMT inhibitors, newly introduced MAO B inhibitors. Also, amantadine had been part of his long-term medication for more than 2 years. The severity of his psychotic symptoms required a L-Dopa monotherapy. After changing his medication, the patient developed severe delirium that resolved rapidly after i.v. amantadine infusion, suggesting an amantadine withdrawal syndrome. Amantadine withdrawal syndrome is a rare adverse event that may present even in PD patients without cognitive impairment. This case report highlights the need for a gradual withdrawal of amantadine even if acute and severe psychotic symptoms are present. Moreover, this is the first report of a cognitively unimpaired patient developing an amantadine withdrawal syndrome.

  15. 20 CFR 404.641 - Cancellation of a request to withdraw.

    Science.gov (United States)

    2010-04-01

    ....641 Section 404.641 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND DISABILITY INSURANCE (1950- ) Filing of Applications and Other Forms Withdrawal of Application § 404.641... received after we have approved the withdrawal, the request is filed no later than 60 days after the date...

  16. Blocking of beta-2 adrenergic receptors hastens recovery from hypoglycemia-associated social withdrawal.

    Science.gov (United States)

    Park, Min Jung; Guest, Christopher B; Barnes, Meredith B; Martin, Jonathan; Ahmad, Uzma; York, Jason M; Freund, Gregory G

    2008-11-01

    Hypoglycemia is associated with a variety of adverse behaviors including fatigue, confusion and social withdrawal. While these clinical symptoms are well characterized, the mechanism of their cause is not understood. Here we investigated how insulin-induced hypoglycemia causes social withdrawal. Male 8-12-week-old C57BL/6J mice were injected intraperitoneally (IP) with or without and/or insulin, norepinephrine (NE) and epinephrine (Epi), terbutaline and butoxamine with subsequent measurement of blood glucose, social withdrawal and plasma catecholamines. Insulin generated (0.75h post-injection) significant hypoglycemia with blood glucose nadirs of 64+/-4 and 48+/-5mg/dl for 0.8 and 1.2units/kg of insulin, respectively. Insulin (0.8 or 1.2units/kg) caused near total social withdrawal at 0.75h with full recovery not occurring until 4h (0.8units/kg) or 8h (1.2units/kg) post-insulin injection. Insulin also caused a marked elevation in plasma catecholamines. Basal 12h fasting NE and Epi were 287+/-38 and 350+/-47pg/ml, respectively. Insulin at 0.8units/kg increased plasma NE and Epi to 994+/-73 and 1842+/-473pg/ml, respectively. Administration of exogenous NE or Epi caused social withdrawal similar in magnitude to insulin. Importantly, administration of the beta-2 adrenergic receptor agonist terbutaline also caused social withdrawal while administration of the beta-2 adrenergic receptor antagonist butoxamine blocked NE-induced social withdrawal. Finally, butoxamine blocked insulin-induced social withdrawal. These data demonstrate that hypoglycemia-associated social withdrawal is dependent on catecholamines via a beta-2 receptor-mediated pathway.

  17. Safety of oral dronabinol during opioid withdrawal in humans.

    Science.gov (United States)

    Jicha, Crystal J; Lofwall, Michelle R; Nuzzo, Paul A; Babalonis, Shanna; Elayi, Samy Claude; Walsh, Sharon L

    2015-12-01

    Opioid dependence remains a significant public health problem worldwide with only three FDA-approved treatments, all targeting the mu-opioid receptor. Dronabinol, a cannabinoid (CB) 1 receptor agonist, is currently under investigation as a novel opioid withdrawal treatment. This study reports on safety outcomes of dronabinol among adults in opioid withdrawal. Twelve adults physically dependent on short-acting opioids participated in this 5-week within-subject, randomized, double blind, placebo-controlled inpatient study. Volunteers were maintained on oral oxycodone 30 mg qid. Double-blind placebo substitutions occurred for 21 h before each of 7 experimental sessions in order to produce opioid withdrawal. A single oral test dose was administered each session (placebo, oxycodone 30 and 60 mg, dronabinol 5, 10, 20, and 30 mg [decreased from 40 mg]). Heart rate, blood pressure, respiratory outcomes and pupil diameter were assessed repeatedly. Dronabinol 40 mg produced sustained sinus tachycardia accompanied by anxiety and panic necessitating dose reduction to 30 mg. Sinus tachycardia and anxiety also occurred in one volunteer after dronabinol 20mg. Compared to placebo, dronabinol 20 and 30 mg produced significant increases in heart rate beginning 1h after drug administration that lasted approximately 2h (popioid agonist effects (e.g., miosis). Dronabinol 20mg and higher increased heart rate among healthy adults at rest who were in a state of opioid withdrawal, raising concern about its safety. These results have important implications for future dosing strategies and may limit the utility of dronabinol as a treatment for opioid withdrawal. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  18. Method for Estimating Water Withdrawals for Livestock in the United States, 2005

    Science.gov (United States)

    Lovelace, John K.

    2009-01-01

    Livestock water use includes ground water and surface water associated with livestock watering, feedlots, dairy operations, and other on-farm needs. The water may be used for drinking, cooling, sanitation, waste disposal, and other needs related to the animals. Estimates of water withdrawals for livestock are needed for water planning and management. This report documents a method used to estimate withdrawals of fresh ground water and surface water for livestock in 2005 for each county and county equivalent in the United States, Puerto Rico, and the U.S. Virgin Islands. Categories of livestock included dairy cattle, beef and other cattle, hogs and pigs, laying hens, broilers and other chickens, turkeys, sheep and lambs, all goats, and horses (including ponies, mules, burros, and donkeys). Use of the method described in this report could result in more consistent water-withdrawal estimates for livestock that can be used by water managers and planners to determine water needs and trends across the United States. Water withdrawals for livestock in 2005 were estimated by using water-use coefficients, in gallons per head per day for each animal type, and livestock-population data. Coefficients for various livestock for most States were obtained from U.S. Geological Survey water-use program personnel or U.S. Geological Survey water-use publications. When no coefficient was available for an animal type in a State, the median value of reported coefficients for that animal was used. Livestock-population data were provided by the National Agricultural Statistics Service. County estimates were further divided into ground-water and surface-water withdrawals for each county and county equivalent. County totals from 2005 were compared to county totals from 1995 and 2000. Large deviations from 1995 or 2000 livestock withdrawal estimates were investigated and generally were due to comparison with reported withdrawals, differences in estimation techniques, differences in livestock

  19. 21 CFR 314.530 - Withdrawal procedures.

    Science.gov (United States)

    2010-04-01

    ... Serious or Life-Threatening Illnesses § 314.530 Withdrawal procedures. (a) For new drugs approved under... benefit; (2) The applicant fails to perform the required postmarketing study with due diligence; (3) Use...

  20. Emplotting Hikikomori: Japanese Parents' Narratives of Social Withdrawal.

    Science.gov (United States)

    Rubinstein, Ellen

    2016-12-01

    Hikikomori, often glossed as "social withdrawal," emerged as a sociomedical condition among Japanese youth at the end of the twentieth century, and it continues to fascinate and concern the public. Explanatory frameworks for hikikomori abound, with different stakeholders attributing it to individual psychopathology, poor parenting, and/or a lack of social support structures. This article takes an interpretive approach to hikikomori by exploring parents' narrative constructions of hikikomori children in support group meetings and in-depth interviews. I argue that some parents were able to find hope in hikikomori by 'emplotting' their children's experiences into a larger narrative about onset, withdrawal, and recovery, which helped them remain invested in the present by maintaining a sense of possibility about the future. Contrary to literature that examines hikikomori as an epidemic of isolated individuals, I demonstrate how parents play a key role in hikikomori through meaning-making activities that have the potential to shape their children's experiences of withdrawal.

  1. Control device for the withdrawal of control rod

    International Nuclear Information System (INIS)

    Ando, Masaki.

    1985-01-01

    Purpose: To significantly suppress the maximum value of the control-rod worth upon control rod withdrawal. Constitution: At first, a signal for designating the first class is sent from a class-control section to the group-control section. In the group-control section, the peripheral group among the first class is designated by which the withdrawal of the control rods other than the peripheral group is inhibited and the control-rods in the peripheral group are withdrawn one by one. When all of them have been withdrawn, the group-control section designates the central group of the first class. All the control rods of the central group have been withdrawn, then the group-control section designates the peripheral group of the second class. Thereafter, the central group in the second class is designated. The control rods are thus withdrawn in the same manner hereinafter. The maximum value for the control-rod worth can be decreased by such a withdrawing sequence for the control rods. (Horiuchi, T.)

  2. Feasibility Study of Economics and Performance of Solar Photovoltaics at the Peru Mill Industrial Park in the City of Deming, New Mexico. A Study Prepared in Partnership with the Environmental Protection Agency for the RE-Powering America's Land Initiative: Siting Renewable Energy on Potentially Contaminated Land and Mine Sites

    Energy Technology Data Exchange (ETDEWEB)

    Kiatreungwattana, K.; Geiger, J.; Healey, V.; Mosey, G.

    2013-04-01

    The U.S. Environmental Protection Agency (EPA), in accordance with the RE-Powering America's Land initiative, selected the Peru Mill Industrial Park site in the City of Deming, New Mexico, for a feasibility study of renewable energy production. The National Renewable Energy Laboratory (NREL) provided technical assistance for this project. The purpose of this report is to assess the site for a possible photovoltaic (PV) system installation and estimate the cost, performance, and site impacts of different PV options. In addition, the report recommends financing options that could assist in the implementation of a PV system at the site.

  3. 40 CFR 96.86 - Withdrawal from NOX Budget Trading Program.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Withdrawal from NOX Budget Trading... PROGRAMS (CONTINUED) NOX BUDGET TRADING PROGRAM AND CAIR NOX AND SO2 TRADING PROGRAMS FOR STATE IMPLEMENTATION PLANS Individual Unit Opt-ins § 96.86 Withdrawal from NOX Budget Trading Program. (a) Requesting...

  4. 20 CFR 410.233 - Cancellation of a request for withdrawal.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Cancellation of a request for withdrawal. 410.233 Section 410.233 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL COAL MINE HEALTH AND... Entitlement; Filing of Claims and Evidence § 410.233 Cancellation of a request for withdrawal. Before or after...

  5. Nicotine Withdrawal Disrupts Contextual Learning but Not Recall of Prior Contextual Associations: Implications for Nicotine Addiction

    OpenAIRE

    Portugal, George S.; Gould, Thomas J.

    2008-01-01

    Interactions between nicotine and learning could contribute to nicotine addiction. Although previous research indicates that nicotine withdrawal disrupts contextual learning, the effects of nicotine withdrawal on contextual memories acquired before withdrawal are unknown. The present study investigated whether nicotine withdrawal disrupted recall of prior contextual memories by examining the effects of nicotine withdrawal on recall of nicotine conditioned place preference (CPP) and contextual...

  6. Socially anxious smokers experience greater negative affect and withdrawal during self-quit attempts.

    Science.gov (United States)

    Buckner, Julia D; Langdon, Kirsten J; Jeffries, Emily R; Zvolensky, Michael J

    2016-04-01

    Despite evidence of a strong and consistent relation between smoking and elevated social anxiety, strikingly little empirical work has identified mechanisms underlying the smoking-social anxiety link. Persons with elevated social anxiety may rely on smoking to cope with more severe nicotine withdrawal and post-quit negative mood states; yet, no known studies have investigated the relation of social anxiety to withdrawal severity. The current study examined the relation of social anxiety to post-quit nicotine withdrawal severity among 51 (33.3% female, Mage = 34.6) community-recruited smokers during the first two weeks following an unaided (i.e., no treatment) cessation attempt. Ecological momentary assessment was used to collect multiple daily ratings of withdrawal and negative mood states. Baseline social anxiety was related to increases in negative affect during the monitoring period and remained significantly related to post-quit withdrawal after controlling for negative affect, gender, lapses, and substance use. Persons with elevated social anxiety experience more severe post-quit withdrawal symptoms and increases in negative affect during a cessation attempt and may therefore benefit from intervention and treatment strategies geared toward helping them learn to cope with withdrawal and negative affect to improve cessation rates among these vulnerable smokers.

  7. Effect of intensive epilimnetic withdrawal on phytoplankton community in a (subtropical deep reservoir

    Directory of Open Access Journals (Sweden)

    Man Zhang

    2013-10-01

    Full Text Available Withdrawal is an important process in reservoir hydrodynamics, removing phytoplankton with flushed water. Zooplankton,the grazers of phytoplankton, having longer generation times, are even more susceptible than phytoplankton to flushing loss. Therefore phytoplankton are affected not only by abiotic conditions linked to hydrodynamics but also by zooplankton due to weakened grazing pressure. During the Asian Games (November 12-27, 2010 in Guangzhou, China, two intensive epilimnetic withdrawals were conducted in Liuxihe, a deep canyon-shaped reservoir. To examine the influence of the intensive epilimnetic withdrawals on the phytoplankton community, a seven-week field observation and a hydrodynamic simulation were carried out. The observation was divided in two stages: stage 1 represented partial surface vertical mixing period, and stage 2 represented intensive epilimnetic withdrawal period. It was found that phytoplankton abundance and biomass declined with water temperature and partial surface vertical mixing in stage 1. However, the intensive epilimnetic withdrawal reversed this decreasing trend and increased phytoplankton biomass and abundance in stage 2. Phytoplankton showed a higher rate of composition change in stage 2. A numerical model (DYRESM-CAEDYM simulated scenarios with and without epilimnetic withdrawal to test their effects on abiotic factors (water temperature, suspended sediment and soluble reactive phosphorus for phytoplankton. The results showed no obvious difference in the abiotic factors between the two scenarios during stage 2. We therefore suggested that the abiotic factors in the water column were probably driven by a seasonal pattern, not by epilimnetic withdrawal. It is likely that the intensive epilimnetic withdrawal could remove large crustaceans. The reduced grazing pressure probably explained the increase of phytoplankton biomass and abundance after the withdrawal. Thus, we suggest that reservoir operation should pay

  8. Parental views on withdrawing life-sustaining therapies in critically ill children.

    Science.gov (United States)

    Michelson, Kelly Nicole; Koogler, Tracy; Sullivan, Christine; Ortega, María del Pilar; Hall, Emily; Frader, Joel

    2009-11-01

    To broaden existing knowledge of pediatric end-of-life decision making by exploring factors described by parents of patients in the pediatric intensive care unit (PICU) as important/influential if they were to consider withdrawing life-sustaining therapies. Quantitative and qualitative analysis of semi-structured one-on-one interviews. The PICUs at 2 tertiary care hospitals. English- or Spanish-speaking parents who were older than 17 years and whose child was admitted to the PICU for more than 24 hours to up to 1 week. Semi-structured one-on-one interviews. Forty of 70 parents (57%) interviewed said they could imagine a situation in which they would consider withdrawing life-sustaining therapies. When asked if specific factors might influence their decision making, 64% of parents said they would consider withdrawing life-sustaining therapies if their child were suffering; 51% would make such a decision based on quality-of-life considerations; 43% acknowledged the influence of physician-estimated prognosis in their decision; and 7% said financial burden would affect their consideration. Qualitative analysis of their subsequent comments identified 9 factors influential to parents when considering withdrawing life-sustaining therapies: quality of life, suffering, ineffective treatments, faith, time, financial considerations, general rejection of withdrawing life-sustaining therapies, mistrust/doubt toward physicians, and reliance on self/intuition. Parents describe a broad range of views regarding possible consideration of withdrawing life-sustaining therapies for their children and what factors might influence such a decision.

  9. Withdrawal and consumption of water by thermoelectric power plants in the United States, 2010

    Science.gov (United States)

    Diehl, Timothy H.; Harris, Melissa A.

    2014-01-01

    Estimates of water use at thermoelectric plants were developed by the U.S. Geological Survey based on linked heat and water budgets, and complement reported thermoelectric water withdrawals and consumption. The heat- and water-budget models produced withdrawal and consumption estimates, including thermodynamically plausible ranges of minimum and maximum withdrawal and consumption, for 1,290 water-using plants in the United States for 2010. Total estimated withdrawal for 2010 was about 129 billion gallons per day (Bgal/d), and total estimated consumption was about 3.5 Bgal/d. In contrast, total withdrawal reported by the U.S. Department of Energy, Energy Information Administration (EIA), was about 24 percent higher than the modeled estimates, and total EIA-reported consumption was about 8 percent lower. Most thermoelectric generation in 2010 was not associated with thermodynamically plausible EIA-reported values of both withdrawal and consumption.

  10. Response to CPAP Withdrawal in Patients with Mild Versus Severe Obstructive Sleep Apnea/Hypopnea Syndrome

    Science.gov (United States)

    Young, Laura R.; Taxin, Zachary H.; Norman, Robert G.; Walsleben, Joyce A.; Rapoport, David M.; Ayappa, Indu

    2013-01-01

    Background: Patients with obstructive sleep apnea/hypopnea syndrome (OSAHS), even those generally compliant with CPAP therapy, often intermittently discontinue CPAP. Study Objective: Examine the impact of CPAP withdrawal on sleep, sleep disordered breathing (SDB), and daytime function in subjects with varying severity of OSAHS. Patients and Interventions: Forty-two subjects (26M/16 F) with OSAHS (AHI4% = 45.2 ± 35.5/h pretreatment) on CPAP for 4 months were evaluated on the second night of CPAP withdrawal. Sleep architecture, SDB indices, and subjective/objective daytime function were assessed pretreatment, on CPAP therapy, and after CPAP withdrawal. Comparisons were made between pretreatment and CPAP withdrawal for the entire group, and for subgroups of mild/moderate (AHI4% 30/h, n = 20) SDB. Results: Overall, and for mild/moderate subjects, SDB indices returned to pretreatment values on CPAP withdrawal but with fewer apneas and more hypopneas/RERAs. For severe SDB, the event frequency (AI, AHI4%, and RDI) was lower and O2 desaturation was improved on CPAP withdrawal. Across SDB severity, sleep architecture showed lower %REM (15.6% vs 12.9%, P = 0.009) on the CPAP withdrawal compared to pretreatment. Stanford Sleepiness Score, MSLT, and PVT measures were not significantly different between pretreatment and CPAP withdrawal. Conclusions: Over a wide range of SDB severity CPAP withdrawal results in recurrence of SDB, albeit with less severe O2 desaturation. Subjective/objective daytime function returned to pretreatment levels. Sleep architecture changes on CPAP withdrawal (acute SDB) may reflect reduced sleep pressure compared to pretreatment chronic SDB. Our data suggest detrimental effects of even brief withdrawal of CPAP in subjects with both mild and severe OSAHS. Citation: Young LR; Taxin ZH; Norman RG; Walsleben JA; Rapoport DM; Ayappa I. Response to CPAP withdrawal in patients with mild versus severe obstructive sleep apnea/hypopnea syndrome. SLEEP 2013

  11. Agroforestry systems in the Sonora River Watershed, Mexico: An example of effective land stewardship

    Science.gov (United States)

    Diego Valdez-Zamudio; Peter F. Ffolliot

    2000-01-01

    The Sonora River watershed is located in the central part of the state of Sonora,Mexico, and is one of the most important watersheds in the region. Much of the state's economy depends on the natural resources, products, and productive activities developed in this watershed. Many natural areas along the river and its tributaries have been converted to a large...

  12. 25 CFR 1200.34 - Can a tribe withdraw redeposited funds?

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false Can a tribe withdraw redeposited funds? 1200.34 Section 1200.34 Indians OFFICE OF THE SPECIAL TRUSTEE FOR AMERICAN INDIANS, DEPARTMENT OF THE INTERIOR AMERICAN INDIAN TRUST FUND MANAGEMENT REFORM ACT Returning Tribal Funds to Trust § 1200.34 Can a tribe withdraw...

  13. Espanola/Canjilon Pilot Study: Economic, social, and cultural aspects of public land grazing on the Santa Fe and Carson National Forests

    Science.gov (United States)

    Carol Raish

    1999-01-01

    Many of the livestock grazing permittees on the Carson and Santa Fe National Forests in northern New Mexico are descendants of Hispanic settlers who have farmed and ranched in the region for 400 years. Much of the permitted land was formerly owned or used by local communities under Spanish and Mexican land grants. Cultural differences and historical issues of...

  14. Peptidase inhibitors reduce opiate narcotic withdrawal signs, including seizure activity, in the rat.

    Science.gov (United States)

    Pinsky, C; Dua, A K; LaBella, F S

    1982-07-15

    Narcotic withdrawal was precipitated by administration of naloxone in a low dose at 2 h after the final dose of morphine in a 9-day dependency-inducing schedule. Withdrawal was characterized by leaps, increased nocifensor activity and by cerebral cortical epileptiform activity, the latter not generally reported to be prominent in narcotic withdrawal. Single large doses of morphine did not provoke epileptiform activity at 2 h postinjection but did induce an acute opioid dependency wherein a moderately high dose of naloxone, ineffective in non-dependent rats, provoked upward leaping and electrocortical epileptiform activity. Pretreatment of the 9-day dependent rats with peptidase inhibitors, administered intracerebroventricularly, significantly reduced withdrawal severity including the epileptiform activity. We propose that peptidase inhibitors protect certain species of endogenous opioids and/or other neuropeptides that tend to suppress expression of the narcotic withdrawal syndrome. Furthermore, our findings suggest that epileptiform activity is a nascent form of cerebral activity hitherto largely unnoticed in narcotic withdrawal and that neuropeptides may be involved in certain epileptic states.

  15. Powering Mexico

    International Nuclear Information System (INIS)

    Anon.

    1992-01-01

    This article examines Mexico's demand for electricity and the market for independent power generation. The topics discussed in the article include the outlook for the 1990s for growth in Mexico's economy and energy demand, renewable energy, energy conservation, small-scale, off-grid renewable energy systems, and estimates of Mexico's market for electric power generating equipment

  16. Oil-spill risk analysis: Central and western Gulf of Mexico Outer Continental Shelf, Lease Sales 139 and 141. Final report

    International Nuclear Information System (INIS)

    Johnson, W.R.; Lear, E.M.

    1992-02-01

    The Federal Government has proposed to offer Outer Continental Shelf lands in the Gulf of Mexico for oil and gas leasing. Because oil spills may occur from activities associated with offshore oil production, the Minerals Management Service conducts a formal risk assessment. The effects of oil spills that could occur during oil and gas production must be considered. The report summarizes results of an oil spill risk analysis conducted for the proposed Gulf of Mexico Outer Continental Shelf Lease Sales 139 and 141

  17. Pollution by organochlorine pesticides in Navachiste-Macapule, Sinaloa, Mexico.

    Science.gov (United States)

    Montes, Adriana M; González-Farias, Fernando A; Botello, Alfonso V

    2012-03-01

    The lagoon system of Navachiste-Macapule is located in northern Mexico, in the state of Sinaloa, with an area of 24,000 ha. The main economic activity in the area is agriculture, and the lagoon lies next to the irrigation district ID-063 which covers 116,615 ha. The purpose of this study is to evaluate the levels of pollution generated by organochlorine pesticides (OC) in the surface sediments of the lagoon and in the agricultural drains of the ID-063 that are supposedly transported into the system as a result of agricultural activities and runoff from adjacent land. For this, between 2006 and 2007, 45 surface sediment samples were collected (warm dry, rainy and cold dry) from 15 sampling sites, during the three climatic seasons. Of these, eight were located inside the lagoon in marine conditions (salinity >31 PSU) and seven in the agricultural drains of the ID-063 in freshwater conditions (salinity Mexico.

  18. Water Resources Response to Climate and Land-Cover Changes in a Semi-Arid Watershed, New Mexico, USA

    Directory of Open Access Journals (Sweden)

    Joonghyeok Heo

    2015-01-01

    Full Text Available This research evaluates a climate-land cover-water resources interconnected system in a semi-arid watershed with minimal human impact from 1970 - 2009. We found _ increase in temperature and 10.9% decrease in precipitation. The temperature exhibited a lower increase trend and precipitation showed a similar decrease trend compared to previous studies. The dominant land-cover change trend was grass and forest conversion into bush/shrub and developed land and crop land into barren and grass land. These alterations indicate that changes in temperature and precipitation in the study area may be linked to changes in land cover, although human intervention is recognized as the major land-cover change contributor for the short term. These alterations also suggest that decreasing human activity in the study area leads to developed land and crop land conversion into barren and grass land. Hydrological responses to climate and land-cover changes for surface runoff, groundwater discharge, soil water content and evapotranspiration decreased by 10.2, 10.0, 4.1, and 10.5%, respectively. Hydrological parameters generally follow similar trends to that of precipitation in semi-arid watersheds with minimal human development. Soil water content is sensitive to land-cover change and offset relatively by the changes in precipitation.

  19. 39 CFR 955.23 - Copies of papers, withdrawal of exhibits.

    Science.gov (United States)

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Copies of papers, withdrawal of exhibits. 955.23... SERVICE BOARD OF CONTRACT APPEALS § 955.23 Copies of papers, withdrawal of exhibits. (a) When books, records, papers, or documents have been received in evidence, a true copy thereof or of such part thereof...

  20. Agent-based modeling of deforestation in southern Yucatán, Mexico, and reforestation in the Midwest United States

    Science.gov (United States)

    Manson, Steven M.; Evans, Tom

    2007-01-01

    We combine mixed-methods research with integrated agent-based modeling to understand land change and economic decision making in the United States and Mexico. This work demonstrates how sustainability science benefits from combining integrated agent-based modeling (which blends methods from the social, ecological, and information sciences) and mixed-methods research (which interleaves multiple approaches ranging from qualitative field research to quantitative laboratory experiments and interpretation of remotely sensed imagery). We test assumptions of utility-maximizing behavior in household-level landscape management in south-central Indiana, linking parcel data, land cover derived from aerial photography, and findings from laboratory experiments. We examine the role of uncertainty and limited information, preferences, differential demographic attributes, and past experience and future time horizons. We also use evolutionary programming to represent bounded rationality in agriculturalist households in the southern Yucatán of Mexico. This approach captures realistic rule of thumb strategies while identifying social and environmental factors in a manner similar to econometric models. These case studies highlight the role of computational models of decision making in land-change contexts and advance our understanding of decision making in general. PMID:18093928

  1. Black bear population and connectivity in the Sky Islands of Mexico and the United States

    Science.gov (United States)

    N. E. Lara-Diaz; C. A. Lopez-Gonzalez; H. Coronel-Arellano; A. Gonzalez-Bernal

    2013-01-01

    The Sky Island region is a mountainous region surrounded by grasslands, deserts and intermountain valleys, located between Mexico and the United States. However, different land management and human impact can have an effect on its wildlife populations. Currently, the border wall poses an immediate threat to the survival of black bears (Ursus americanus), considered an...

  2. On the relationship between Indian monsoon withdrawal and Iran's fall precipitation onset

    Science.gov (United States)

    Babaeian, Iman; Rezazadeh, Parviz

    2017-09-01

    Indian monsoon is the most prominent of the world's monsoon systems which primarily affects synoptic patterns of India and adjacent countries such as Iran in interaction with large-scale weather systems. In this article, the relationship between the withdrawal date of the Indian monsoon and the onset of fall precipitation in Iran has been studied. Data included annual time series of withdrawal dates of the Indian monsoon prepared by the Indian Institute for Tropical Meteorology, and time series of the first date of 25 mm accumulated precipitation over Iran's synoptic weather stations in a 10-day period which is the basis for the cultivation date. Both time series were considered in Julian calendar with the starting date on August 1. The studied period is 1960-2014 which covers 55 years of data from 36 meteorological stations in Iran. By classifying the withdrawal dates of the Indian monsoon in three stages of late, normal, and early withdrawals, its relation with the onset of fall precipitation in western, southwestern, southern, eastern, central, and northern regions of Iran was studied. Results demonstrated that in four out of the six mentioned regions, the late withdrawal of the Indian monsoon postpones the onset of fall precipitation over Iran. No significant relation was found between the onset of fall precipitation in central region of Iran and the monsoon's withdrawal date. In the western, southwestern, southern, and eastern regions of Iran, the late monsoon delays the onset of fall's precipitation; while in the south Caspian Sea coastal area, it causes the early onset of autumnal precipitation. The lag in onset of fall precipitation in Iran which is coordinated with the late withdrawal of monsoon is accompanied with prolonged subtropical high settling over Iran's plateau that prevents the southward movement of polar jet frontal systems. Such conditions enhance northerly wind currents over the Caspian Sea which, in turn, increase the precipitation in Caspian

  3. The role of spiritual intelligence in employees’ withdrawal behaviors in physical education organization

    Directory of Open Access Journals (Sweden)

    Davoud Noroozi

    2015-03-01

    Full Text Available Spiritual intelligence is the mind’s capacity to handle substantial and spiritual aspects of life. According to previous studies, spiritual intelligence can be effective in reducing the withdrawal behavior of employees. This study investigated the effect of spiritual intelligence on employees’ withdrawal behavior in Ardabil Physical Education organization. The statistical population of this study included all the employees of Physical Education organization of Ardabil (N=60. Descriptive Statistics, Pearson Correlation, and Linear Regression Analyses were used to assess the association between spiritual intelligence and withdrawal behaviors. The results of the study revealed that spiritual intelligence had positive and significant effect on reducing employees’ withdrawal behavior. The findings supported that spiritual intelligence training as a new psychological and religious construction may reduce psychological and physical withdrawal behaviors and improve the employees’ perception of themselves.

  4. Sustainability of coastal resource use in San Quintin, Mexico.

    Science.gov (United States)

    Aguirre-Muñoz, A; Buddemeier, R W; Camacho-Ibar, V; Carriquiry, J D; Ibarra-Obando, S E; Massey, B W; Smith, S V; Wulff, F

    2001-05-01

    San Quintin, Mexico, provides a useful site for integrated analyses of material fluxes and socioeconomic constraints in a geographically isolated system. Natural resource utilization on the land is dominated by groundwater exploitation for cultivation of horticulture crops (primarily tomatoes). Irrigation exceeds water recharge minus export by a factor of 6. Resource utilization in the bay is dominated by oyster culture; food for the oysters is provided by tidal exchange of bay and ocean water. Consideration of oyster respiration and system respiration suggests that the present level of aquaculture is about 40% of the sustainable level. A "physical unsustainability index" (PhUI) was developed to measure the proportional departure of utilization of the most limiting resource for sustainability: 6 on land; 0.4 in the bay. Based on PhUI and measures of economic development, we conclude that aquaculture is more viable than agriculture.

  5. Feed withdrawal and transportation effects on Salmonella enterica levels in market-weight pigs.

    Science.gov (United States)

    Eicher, S D; Rostagno, M H; Lay, D C

    2017-07-01

    Feed withdrawal and transport commonly occur together in pigs. Objectives of this study were to determine if these preslaughter stressors, feed withdrawal and transportation, affect the levels of , stress hormone concentrations, and immune functions in infected market pigs. A 2 × 2 factorial analysis of a randomized complete block design with feed withdrawal and transport as fixed effects was used. Sixty market-weight pigs were individually inoculated with serovar Typhimurium. The experiment was replicated 3 times (blocking factor) with 20 pigs per replicate. Three days after inoculation, the pigs were randomly assigned to 1 of 4 treatments (5 pigs per treatment in each/replicate), including 1) control (Control; or no stress), 2) feed withdrawal for 12 h (FW), 3) transportation for 2 h (T), and 4) feed withdrawal for 12 h followed by transportation for 2 h (FWT). Feed withdrawal by itself or followed by transportation caused an increase of levels in ileal contents ( 0.10). Cortisol increased in pigs from all 3 stress treatments ( 0.03). Each granulocyte percentage (neutrophil, eosinophils, and basophils) increased ( transport but was attenuated ( > 0.05) by feed withdrawal with transport. Lymphocytes were suppressed ( transported (T and FWT). However, monocytes were suppressed ( transportation, lead to greater intestinal levels and gut-associated lymphoid tissue markers of inflammation in market pigs and, consequently, to an increased food safety risk.

  6. Timing of nicotine lozenge administration to minimize trigger induced craving and withdrawal symptoms.

    Science.gov (United States)

    Kotlyar, Michael; Lindgren, Bruce R; Vuchetich, John P; Le, Chap; Mills, Anne M; Amiot, Elizabeth; Hatsukami, Dorothy K

    2017-08-01

    Smokers are often advised to use nicotine lozenge when craving or withdrawal symptoms occur. This may be too late to prevent lapses. This study assessed if nicotine lozenge use prior to a common smoking trigger can minimize trigger induced increases in craving and withdrawal symptoms. Eighty-four smokers completed two laboratory sessions in random order. At one session, nicotine lozenge was given immediately after a stressor (to approximate current recommended use - i.e., after craving and withdrawal symptoms occur); at the other session subjects were randomized to receive nicotine lozenge at time points ranging from immediately to 30min prior to the stressor. Withdrawal symptoms and urge to smoke were measured using the Minnesota Nicotine Withdrawal Scale and the Questionnaire of Smoking Urges (QSU). Relative to receiving lozenge after the stressor, a smaller increase in pre-stressor to post-stressor withdrawal symptom scores occurred when lozenge was used immediately (p=0.03) and 10min prior (p=0.044) to the stressor. Results were similar for factors 1 and 2 of the QSU when lozenge was used immediately prior to the stressor (pnicotine lozenge prior to a smoking trigger can decrease trigger induced craving and withdrawal symptoms. Future studies are needed to determine if such use would increase cessation rates. Clinicaltrials.gov # NCT01522963. Copyright © 2017 Elsevier Ltd. All rights reserved.

  7. Social transfer of alcohol withdrawal-induced hyperalgesia in female prairie voles.

    Science.gov (United States)

    Walcott, Andre T; Smith, Monique L; Loftis, Jennifer M; Ryabinin, Andrey E

    2018-03-27

    The expression of pain serves as a way for animals to communicate potential dangers to nearby conspecifics. Recent research demonstrated that mice undergoing alcohol or morphine withdrawal, or inflammation, could socially communicate their hyperalgesia to nearby mice. However, it is unknown whether such social transfer of hyperalgesia can be observed in other species of rodents. Therefore, the present study investigated if the social transfer of hyperalgesia occurs in the highly social prairie vole (Microtus ochrogaster). We observe that adult female prairie voles undergoing withdrawal from voluntary two-bottle choice alcohol drinking display an increase in nociception. This alcohol withdrawal-induced hypersensitiity is socially transferred to female siblings within the same cage and female strangers housed in separate cages within the same room. These experiments reveal that the social transfer of pain phenomenon is not specific to inbred mouse strains and that prairie voles display alcohol withdrawal and social transfer-induced hyperalgesia.

  8. Interpreting compositional zonation of the Zaragoza ignimbrite from Los Humeros caldera, Central Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Carrasco-Nunez, Gerardo [Centro de Geociencias, UNAM, Campus Juriquilla, Queretaro, Qro. (Mexico); McCurry, Michael [Department of Geology, Idaho State University, Pocatello, ID (United States); Branney, Michael J [Department of Geology, University of Leicester, Leicester (United Kingdom)

    2008-10-01

    Compositional zonation in ignimbrites is relatively common, and is often inferred to record gradual withdrawal by an eruption of a density-stratified magma chamber (with silicic magma towards the top and more dense, mafic magma at the bottom). We show that this model does not match observations at the ca. 0.1 Ma Zaragoza ignimbrite from Los Humeros caldera in central Mexico. Detailed petrologic studies reveal a more complex scenario: the ignimbrite exhibits a 'double' vertical zonation based on the compositions of pumice lapilli. We present evidence for mingling and limited mixing occurred during or immediately before the caldera-forming eruption. One possibility to explain the observations is that the ignimbrite eruption occurred in response to intrusion of a hybridized andesitic magma into a rhyodacitic magma chamber.

  9. Assessment of Land Use-Cover Changes and Successional Stages of Vegetation in the Natural Protected Area Altas Cumbres, Northeastern Mexico, Using Landsat Satellite Imagery

    Directory of Open Access Journals (Sweden)

    Uriel Jeshua Sánchez-Reyes

    2017-07-01

    Full Text Available Loss of vegetation cover is a major factor that endangers biodiversity. Therefore, the use of geographic information systems and the analysis of satellite images are important for monitoring these changes in Natural Protected Areas (NPAs. In northeastern Mexico, the Natural Protected Area Altas Cumbres (NPAAC represents a relevant floristic and faunistic patch on which the impact of loss of vegetation cover has not been assessed. This work aimed to analyze changes of land use and coverage (LULCC over the last 42 years on the interior and around the exterior of the area, and also to propose the time of succession for the most important types of vegetation. For the analysis, LANDSAT satellite images from 1973, 1986, 2000, 2005 and 2015 were used, they were classified in seven categories through a segmentation and maximum likelihood analysis. A cross-tabulation analysis was performed to determine the succession gradient. Towards the interior of the area, a significant reduction of tropical vegetation and, to a lesser extent, temperate forests was found, as well as an increase in scrub cover from 1973 to 2015. In addition, urban and vegetation-free areas, as well as modified vegetation, increased to the exterior. Towards the interior of the NPA, the processes of perturbation and recovery were mostly not linear, while in the exterior adjacent area, the presence of secondary vegetation with distinct definite time of succession was evident. The analysis carried out is the first contribution that evaluates LULCC in this important NPA of northeastern Mexico. Results suggest the need to evaluate the effects of these modifications on species.

  10. Parental Views on Withdrawing Life-Sustaining Therapies in Critically Ill Children

    Science.gov (United States)

    Michelson, Kelly Nicole; Koogler, Tracy; Sullivan, Christine; del Pilar Ortega, María; Hall, Emily; Frader, Joel

    2009-01-01

    Objective To broaden existing knowledge of pediatric end-of-life decision making by exploring factors described by parents of patients in the pediatric intensive care unit (PICU) as important/influential if they were to consider withdrawing life-sustaining therapies. Design Quantitative and qualitative analysis of semi-structured one-on-one interviews. Setting The PICUs at 2 tertiary care hospitals. Participants English- or Spanish-speaking parents who were older than 17 years and whose child was admitted to the PICU for more than 24 hours to up to 1 week. Intervention Semi-structured one-on-one interviews. Results Forty of 70 parents (57%) interviewed said they could imagine a situation in which they would consider withdrawing life-sustaining therapies. When asked if specific factors might influence their decision making, 64% of parents said they would consider withdrawing life-sustaining therapies if their child were suffering; 51% would make such a decision based on quality-of-life considerations; 43% acknowledged the influence of physician-estimated prognosis in their decision; and 7% said financial burden would affect their consideration. Qualitative analysis of their subsequent comments identified 9 factors influential to parents when considering withdrawing life-sustaining therapies: quality of life, suffering, ineffective treatments, faith, time, financial considerations, general rejection of withdrawing life-sustaining therapies, mistrust/doubt toward physicians, and reliance on self/intuition. Conclusion Parents describe a broad range of views regarding possible consideration of withdrawing life-sustaining therapies for their children and what factors might influence such a decision. PMID:19884588

  11. Shallow Faulting in Morelia, Mexico, Based on Seismic Tomography and Geodetically Detected Land Subsidence

    Science.gov (United States)

    Cabral-Cano, E.; Arciniega-Ceballos, A.; Vergara-Huerta, F.; Chaussard, E.; Wdowinski, S.; DeMets, C.; Salazar-Tlaczani, L.

    2013-12-01

    Subsidence has been a common occurrence in several cities in central Mexico for the past three decades. This process causes substantial damage to the urban infrastructure and housing in several cities and it is a major factor to be considered when planning urban development, land-use zoning and hazard mitigation strategies. Since the early 1980's the city of Morelia in Central Mexico has experienced subsidence associated with groundwater extraction in excess of natural recharge from rainfall. Previous works have focused on the detection and temporal evolution of the subsidence spatial distribution. The most recent InSAR analysis confirms the permanence of previously detected rapidly subsiding areas such as the Rio Grande Meander area and also defines 2 subsidence patches previously undetected in the newly developed suburban sectors west of Morelia at the Fraccionamiento Del Bosque along, south of Hwy. 15 and another patch located north of Morelia along Gabino Castañeda del Rio Ave. Because subsidence-induced, shallow faulting develops at high horizontal strain localization, newly developed a subsidence areas are particularly prone to faulting and fissuring. Shallow faulting increases groundwater vulnerability because it disrupts discharge hydraulic infrastructure and creates a direct path for transport of surface pollutants into the underlying aquifer. Other sectors in Morelia that have been experiencing subsidence for longer time have already developed well defined faults such as La Colina, Central Camionera, Torremolinos and La Paloma faults. Local construction codes in the vicinity of these faults define a very narrow swath along which housing construction is not allowed. In order to better characterize these fault systems and provide better criteria for future municipal construction codes we have surveyed the La Colina and Torremolinos fault systems in the western sector of Morelia using seismic tomographic techniques. Our results indicate that La Colina Fault

  12. To Withdraw Or Not To Withdraw? Evaluation of the Mandatory Right of Withdrawal in Consumer Distance Selling Contracts Taking Into Account Its Behavioural Effects on Consumers

    NARCIS (Netherlands)

    Luzak, J.A.

    2014-01-01

    The right of withdrawal was introduced to European consumer law as an exception to the general contractual principle of pacta sunt servanda. It has recently been upheld in the Consumer Rights Directive as a mandatory right for consumers concluding distance selling contracts. Among various

  13. 29 CFR 4211.35 - Direct attribution method for withdrawals after the initial plan year.

    Science.gov (United States)

    2010-07-01

    ... WITHDRAWING EMPLOYERS Allocation Methods for Merged Multiemployer Plans § 4211.35 Direct attribution method for withdrawals after the initial plan year. The allocation method under this section is the... 29 Labor 9 2010-07-01 2010-07-01 false Direct attribution method for withdrawals after the initial...

  14. USA Withdrawal from Paris Agreement – What Next?

    Directory of Open Access Journals (Sweden)

    Sergey Chestnoy

    2017-12-01

    Full Text Available In June 2017, President Trump announced the USA’s withdrawal from the Paris Climate Accord, which had been ratified for less than a year, thanks in large part to the USA. That drastic shift followed the change in residency at the White House. Withdrawing from the Paris Accord presents an interesting topic for analysis. There’s the practical side of the withdrawal procedure as set out in Article 28 of the agreement, not to mention the consequences of US non-participation in addressing international climate issues. There are other international forums (Such as G8 and G20, which also have an interest in climate related topics. The Article analyses the U.S. position in negotiations and its commitments assumed the moment the United Nations Framework Convention on Climate Change (UNFCCC came into effect until now: the reduction of greenhouse gas emissions, financial aid and reporting. It also provides general analysis of national legal obligations under the Paris Accord, ratification of that agreement in general and in particularly another that took place in the USA, it focuses on the specifics of withdrawal. The specified three-year period from the Agreement becoming active, after which any party may withdraw from it (2019, is a noteworthy detail. It is well-known that the Paris Agreement provides a framework that does not impose individual national commitments or a commitment to a compliance system. In essence, and from a legal point of view, it is nonbinding. This was what allowed the USA to accept the terms of the accord relatively quickly and to use the simplified procedure, which by-passed Congress. In the opinion of the authors, President Trump’s resolution to withdraw should, possibly, be considered as a simple continuation of his election discourse and the fulfilment of a campaign promise. Additionally, President Trump’s declared intent to review the Paris Accord has legal grounds on which to launch further international negotiations

  15. Fearfulness moderates the link between childhood social withdrawal and adolescent reward response.

    Science.gov (United States)

    Morgan, Judith K; Shaw, Daniel S; Forbes, Erika E

    2015-06-01

    Withdrawal from peers during childhood may reflect disruptions in reward functioning that heighten vulnerability to affective disorders during adolescence. The association between socially withdrawn behavior and reward functioning may depend on traits that influence this withdrawal, such as fearfulness or unsociability. In a study of 129 boys, we evaluated how boys' fearfulness and sociability at age 5 and social withdrawal at school at ages 6 to 10 and during a summer camp at age 9/10 were associated with their neural response to reward at age 20. Greater social withdrawal during childhood was associated with heightened striatal and mPFC activation when anticipating rewards at age 20. Fearfulness moderated this effect to indicate that social withdrawal was associated with heightened reward-related response in the striatum for boys high on fearfulness. Altered striatal response associated with social withdrawal and fearfulness predicted greater likelihood to have a lifetime history of depression and social phobia at age 20. These findings add greater specificity to previous findings that children high in traits related to fear of novelty show altered reward responses, by identifying fearfulness (but not low levels of sociability) as a potential underlying mechanism that contributes to reward alterations in withdrawn children. © The Author (2014). Published by Oxford University Press. For Permissions, please email: journals.permissions@oup.com.

  16. U.S. withdrawal from the Paris Agreement: Reasons, impacts, and China's response

    Directory of Open Access Journals (Sweden)

    Hai-Bin Zhang

    2017-12-01

    Full Text Available Applying qualitative and quantitative methods, this article explains the driving forces behind U.S. President Donald Trump's decision to withdraw from the Paris Agreement, assesses the impacts of this withdrawal on the compliance prospects of the agreement, and proposes how China should respond. The withdrawal undercuts the foundation of global climate governance and upsets the process of climate cooperation, and the impacts are manifold. The withdrawal undermines the universality of the Paris Agreement and impairs states' confidence in climate cooperation; it aggravates the leadership deficit in addressing global climate issues and sets a bad precedent for international climate cooperation. The withdrawal reduces other countries' emission space and raises their emission costs, and refusal to contribute to climate aid makes it more difficult for developing countries to mitigate and adapt to climate change. Cutting climate research funding will compromise the quality of future IPCC reports and ultimately undermine the scientific authority of future climate negotiations. China faces mounting pressure from the international community to assume global climate leadership after the U.S. withdraws, and this article proposes that China should reach the high ends of its domestic climate targets under the current Nationally Determined Contributions; internationally, China should facilitate the rebuilding of shared climate leadership, replacing the G2 with C5. Meanwhile, China needs to keep the U.S. engaged in climate cooperation.

  17. Radionuclide withdrawal from animal and human body

    International Nuclear Information System (INIS)

    Arkhipov, A.S.; Sidorova, T.F.

    1995-01-01

    The authors review the history of the problem of radionuclide withdrawal from animal and human body and discuss methodological approaches to it. Results of studies of radionuclide elimination by means of chemical and bioactive substances are analyzed. Special attention is paid to decorporation of radioactive elements which are the most hazardous as regards intoxication in connection with the Chernobyl accident: 131 I, 89 St and 90 Sr, 137 Cs, 238 Pu, and 241 Am. The authors analyze the results of studies of radionuclide withdrawal based on the dissolution effect, ionic antagonism, and by means of complexons, carried out in humans and animals. Efficacies of alimentary fibers and other adsorbents, foodstuffs and drinks are demonstrated. 48 refs

  18. Reconstruction of global gridded monthly sectoral water withdrawals for 1971-2010 and analysis of their spatiotemporal patterns

    Science.gov (United States)

    Huang, Zhongwei; Hejazi, Mohamad; Li, Xinya; Tang, Qiuhong; Vernon, Chris; Leng, Guoyong; Liu, Yaling; Döll, Petra; Eisner, Stephanie; Gerten, Dieter; Hanasaki, Naota; Wada, Yoshihide

    2018-04-01

    Human water withdrawal has increasingly altered the global water cycle in past decades, yet our understanding of its driving forces and patterns is limited. Reported historical estimates of sectoral water withdrawals are often sparse and incomplete, mainly restricted to water withdrawal estimates available at annual and country scales, due to a lack of observations at seasonal and local scales. In this study, through collecting and consolidating various sources of reported data and developing spatial and temporal statistical downscaling algorithms, we reconstruct a global monthly gridded (0.5°) sectoral water withdrawal dataset for the period 1971-2010, which distinguishes six water use sectors, i.e., irrigation, domestic, electricity generation (cooling of thermal power plants), livestock, mining, and manufacturing. Based on the reconstructed dataset, the spatial and temporal patterns of historical water withdrawal are analyzed. Results show that total global water withdrawal has increased significantly during 1971-2010, mainly driven by the increase in irrigation water withdrawal. Regions with high water withdrawal are those densely populated or with large irrigated cropland production, e.g., the United States (US), eastern China, India, and Europe. Seasonally, irrigation water withdrawal in summer for the major crops contributes a large percentage of total annual irrigation water withdrawal in mid- and high-latitude regions, and the dominant season of irrigation water withdrawal is also different across regions. Domestic water withdrawal is mostly characterized by a summer peak, while water withdrawal for electricity generation has a winter peak in high-latitude regions and a summer peak in low-latitude regions. Despite the overall increasing trend, irrigation in the western US and domestic water withdrawal in western Europe exhibit a decreasing trend. Our results highlight the distinct spatial pattern of human water use by sectors at the seasonal and annual

  19. Spatial and temporal variability in fire occurrence within the Las Bayas Forestry Reserve, Durango, Mexico

    Science.gov (United States)

    S. A. Drury; T. T. Veblen

    2008-01-01

    Patterns of fire occurrence within the Las Bayas Forestry Reserve, Mexico are analyzed in relation to variability in climate, topography, and human land-use. Significantly more fires with shorter fire return intervals occurred from 1900 to 1950 than from 1950 to 2001. However, the frequency of widespread fire years (25% filter) was unchanged over time, as widespread...

  20. FACTORS INFLUENCING DECISIONS FOR USING OUTSIDE FUNDS FOR FARM INVESTMENTS AND PROPRIETOR WITHDRAWALS BY SMALL-SCALE FARMERS IN ABIA STATE, NIGERIA

    Directory of Open Access Journals (Sweden)

    Chriso O. EMEROLE

    2013-08-01

    Full Text Available This study on factors influencing decisions for using outside funds for Farm investments and for proprietor withdrawals was carried out among rural small-scale farm households in Abia state, Nigeria. A cross-sectional survey of ninety (90 rural farm households of multi-type (varied enterprises was carried out using cluster random sampling technique in three communities, each chosen from one of the three agricultural zones of the state. Results indicated rural household level variables that positively influenced decisions to source farm investment fund to include level of education, gender, membership of cooperative society, interest charge, land acquisition method, and ease of getting loan. Other factors that negatively influenced decisions include farming as major occupation, household savings, household size, and distance of farmers’ home to source of credit. Proprietor withdrawal decisions were positively influenced by household level variables like taking farming as major occupation, payment of school fees for children of farmers, and amount of credit so far repaid by a farm household. Other factors namely household size, being member of cooperative society or savings group, interest charges on loan, off-farm income, and household savings had negative influences on proprietor withdrawal decisions. We recommended that small-scale farmers should not borrow their start-up capital from outside their households but as their farm businesses stabilize, they could decide to take loans from outside to cover their working capital and/or expand their farms and be prepared to repay such loans according to contractual agreements.

  1. Valence evaluation with approaching or withdrawing cues: directly testing valence-arousal conflict theory.

    Science.gov (United States)

    Wang, Yan Mei; Li, Ting; Li, Lin

    2017-07-19

    The valence-arousal conflict theory assumes that both valence and arousal will trigger approaching or withdrawing tendencies. It also predicts that the speed of processing emotional stimuli will depend on whether valence and arousal trigger conflicting or congruent motivational tendencies. However, most previous studies have provided evidence of the interaction between valence and arousal only, and have not provided direct proof of the interactive links between valence, arousal and motivational tendencies. The present study provides direct evidence for the relationship between approach-withdrawal tendencies and the valence-arousal conflict. In an empirical test, participants were instructed to judge the valence of emotional words after visual-spatial cues that appeared to be either approaching or withdrawing from participants. A three-way interaction (valence, arousal, and approach-withdrawal tendency) was observed such that the response time was shorter if participants responded to a negative high-arousal stimulus after a withdrawing cue, or to a positive low-arousal stimulus after an approaching cue. These findings suggest that the approach-withdrawal tendency indeed plays a crucial role in valence-arousal conflict, and that the effect depends on the congruency of valence, arousal and tendency at an early stage of processing.

  2. The social side of shame: approach versus withdrawal.

    Science.gov (United States)

    de Hooge, Ilona E; Breugelmans, Seger M; Wagemans, Fieke M A; Zeelenberg, Marcel

    2018-01-05

    At present, the consequences and functions of experiences of shame are not yet well understood. Whereas psychology literature typically portrays shame as being bad for social relations, motivating social avoidance and withdrawal, there are recent indications that shame can be reinterpreted as having clear social tendencies in the form of motivating approach and social affiliation. Yet, until now, no research has ever put these alternative interpretations of shame-motivated behaviours directly to the test. The present paper presents such a test by studying the extent to which shame motivates a preference for social withdrawal versus a preference for social approach. Two studies (N = 148 and N = 133) using different shame inductions both showed people experiencing shame to prefer to be together with others (social approach) over being alone (social withdrawal). In addition, the preference for a social situation was found to be unique for shame; it was not found for the closely related emotion of guilt. Taken together, these findings provide direct empirical support for the idea that shame can have positive interpersonal consequences.

  3. Nature cures nature: Hypericum perforatum attenuates physical withdrawal signs in opium dependent rats.

    Science.gov (United States)

    Khan, Munasib; Subhan, Fazal; Khan, Arif-Ullah; Abbas, Muzaffar; Ali, Gowhar; Rauf, Khalid; Gilani, Anwarul Hassan

    2014-05-01

    Hypericum perforatum Linn. (Hypericaceae) (St. John's wort) attenuates opium withdrawal signs. To explore the therapeutic potential of Hypericum perforatum in the management of opium-induced withdrawal syndrome. The effect of the Hypericum perforatum hydro-ethanol extract was investigated for potential to reverse naloxone (0.25 mg/kg)-induced opium withdrawal physical signs. Rats received opium extract (80-650 mg/kg) twice daily for 8 days along with Hypericum perforatum (20 mg/kg, orally) twice daily in chronic treatment and the same single dose 1 h before induction of withdrawal syndrome in the acute treated group. Hypericum perforatum reduced stereotype jumps and wet dog shake number in the chronic treatment compared to the saline control group (F(2, 24) = 3.968, p opium withdrawal syndrome possibly through direct or indirect interaction with opioid receptors. Further study is needed to clarify its mechanism.

  4. Tolerance and withdrawal to anticonvulsant action of clonazepam: role of nitric oxide.

    Science.gov (United States)

    Gupta, N; Bhargava, V K; Pandhi, P

    2000-05-01

    The use of clonazepam in the long-term treatment of epilepsy is greatly inhibited by its capacity to induce tolerance and dependence. A means of preventing or minimizing the tolerance and dependence inducing properties is required. Here the role of nitric oxide in preventing the development of tolerance and withdrawal hyperexcitability was studied. In Wistar rats, clonazepam at a dose of 0.25 mg/kg i.p. twice daily produced tolerance to its anticonvulsant action in 28 days. After sudden cessation of therapy it produced hyperexcitability. Tolerance was shown by a decrease in seizure threshold to near control value while withdrawal hyperexcitability was evidenced by a significant decrease in seizure threshold below the control value. L-Arginine (a donor of nitric oxide) and N omega-nitro-L-arginine (an inhibitor of nitric oxide synthase) were given in doses of 150 mg/kg and 8 mg/kg, respectively on day 1, 3, 7, 14, 21 and 28 with clonazepam. Withdrawal hyperexcitability was seen on day 1, 2 and 4 after cessation of drug therapy. Electroshock was used as a model of epilepsy and seizure thresholds were determined by an up and down method of Kimball et al. L-Arginine was found to inhibit the development tolerance as well as withdrawal hyperexcitability when administered with clonazepam while N omega-L-arginine did not prevent either the development of tolerance or withdrawal hyperexcitability in the electroshock model. In the PTZ model, however, L-arginine had no effect on the anticonvulsant action and withdrawal hyperexcitability while inhibition of nitric oxide synthesis prevented withdrawal hyperexcitability in PTZ-induced seizures.

  5. Clinical relevance of "withdrawal therapy" as a form of hormonal manipulation for breast cancer

    Directory of Open Access Journals (Sweden)

    Robertson John FR

    2011-09-01

    Full Text Available Abstract Background It has been shown in in-vitro experiments that "withdrawal" of tamoxifen inhibits growth of tumor cells. However, evidence is scarce when this is extrapolated into clinical context. We report our experience to verify the clinical relevance of "withdrawal therapy". Methods Breast cancer patients since 1998 who fulfilled the following criteria were selected from the departmental database and the case-notes were retrospectively reviewed: (1 estrogen receptor positive, operable primary breast cancer in elderly (age > 70 years, locally advanced or metastatic breast cancer; (2 disease deemed suitable for treatment by hormonal manipulation; (3 disease assessable by UICC criteria; (4 received "withdrawal" from a prior endocrine agent as a form of therapy; (5 on "withdrawal therapy" for ≥ 6 months unless they progressed prior. Results Seventeen patients with median age of 84.3 (53.7-92.5 had "withdrawal therapy" as second to tenth line of treatment following prior endocrine therapy using tamoxifen (n = 10, an aromatase inhibitor (n = 5, megestrol acetate (n = 1 or fulvestrant (n = 1. Ten patients (58.8% had clinical benefit (CB (complete response/partial response/stable disease ≥ 6 months with a median duration of Clinical Benefit (DoCB of 10+ (7-27 months. Two patients remain on "withdrawal therapy" at the time of analysis. Conclusion "Withdrawal therapy" appears to produce sustained CB in a significant proportion of patients. This applies not only to "withdrawal" from tamoxifen, but also from other categories of endocrine agents. "Withdrawal" from endocrine therapy is, therefore, a viable intercalating option between endocrine agents to minimise resistance and provide additional line of therapy. It should be considered as part of the sequencing of endocrine therapy.

  6. 10 CFR 95.21 - Withdrawal of requests for facility security clearance.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Withdrawal of requests for facility security clearance. 95.21 Section 95.21 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) FACILITY SECURITY CLEARANCE AND SAFEGUARDING OF NATIONAL SECURITY INFORMATION AND RESTRICTED DATA Physical Security § 95.21 Withdrawal of...

  7. Efficacy of Tramadol Extended-Release for Opioid Withdrawal: A Randomized Clinical Trial.

    Science.gov (United States)

    Dunn, Kelly E; Tompkins, D Andrew; Bigelow, George E; Strain, Eric C

    2017-09-01

    Opioid use disorder (OUD) is a significant public health problem. Supervised withdrawal (ie, detoxification) from opioids using clonidine or buprenorphine hydrochloride is a widely used treatment. To evaluate whether tramadol hydrochloride extended-release (ER), an approved analgesic with opioid and nonopioid mechanisms of action and low abuse potential, is effective for use in supervised withdrawal settings. A randomized clinical trial was conducted in a residential research setting with 103 participants with OUD. Participants' treatment was stabilized with morphine, 30 mg, administered subcutaneously 4 times daily. A 7-day taper using clonidine (n = 36), tramadol ER (n = 36), or buprenorphine (n = 31) was then instituted, and patients were crossed-over to double-blind placebo during a post-taper period. The study was conducted from October 25, 2010, to June 23, 2015. Retention, withdrawal symptom management, concomitant medication utilization, and naltrexone induction. Results were analyzed over time and using area under the curve for the intention-to-treat and completer groups. Of the 103 participants, 88 (85.4%) were men and 43 (41.7%) were white; mean (SD) age was 28.9 (10.4) years. Buprenorphine participants (28 [90.3%]) were significantly more likely to be retained at the end of the taper compared with clonidine participants (22 [61.1%]); tramadol ER retention was intermediate and did not differ significantly from that of the other groups (26 [72.2%]; χ2 = 8.5, P = .01). Time-course analyses of withdrawal revealed significant effects of phase (taper, post taper) for the Clinical Opiate Withdrawal Scale (COWS) score (taper mean, 5.19 [SE, .26]; post-taper mean, 3.97 [SE, .23]; F2,170 = 3.6, P = .03) and Subjective Opiate Withdrawal Scale (SOWS) score (taper mean,8.81 [SE, .40]; post-taper mean, 4.14 [SE, .30]; F2,170 = 15.7, P withdrawal severity between the taper and post-taper periods for clonidine (taper mean, 13.1; post

  8. Transporting transuranic waste to the Waste Isolation Pilot Plant: Risk and cost perspectives

    International Nuclear Information System (INIS)

    Biwer, B. M.; Gilette, J. L.; Poch, L. A.; Suermann, J. F.

    1999-01-01

    The Waste Isolation Pilot Plant (WIPP) is an authorized US Department of Energy (DOE) research and development facility constructed near the city of Carlsbad in southeastern New Mexico. The facility is intended to demonstrate the safe disposal of transuranic (TRU) radioactive waste resulting from US defense activities. Under the WIPP Land Withdrawal Act of 1992 (LWA), federal lands surrounding the WIPP facility were withdrawn from all public use and the title of those lands was transferred to the Secretary of Energy. The DOE's TRU waste is stored, and in some cases is still being generated, at 10 large-quantity and 13 small-quantity sites across the US. After applicable certification requirements have been met, the TRU waste at these sites will be sent to the WIPP to initiate the disposal phase of the facility, which according to current planning is projected to last for approximately 35 years

  9. Evidence of Incipient Forest Transition in Southern Mexico

    Science.gov (United States)

    Vaca, Raúl Abel; Golicher, Duncan John; Cayuela, Luis; Hewson, Jenny; Steininger, Marc

    2012-01-01

    Case studies of land use change have suggested that deforestation across Southern Mexico is accelerating. However, forest transition theory predicts that trajectories of change can be modified by economic factors, leading to spatial and temporal heterogeneity in rates of change that may take the form of the Environmental Kuznets Curve (EKC). This study aimed to assess the evidence regarding potential forest transition in Southern Mexico by classifying regional forest cover change using Landsat imagery from 1990 through to 2006. Patterns of forest cover change were found to be complex and non-linear. When rates of forest loss were averaged over 342 municipalities using mixed-effects modelling the results showed a significant (p<0.001) overall reduction of the mean rate of forest loss from 0.85% per year in the 1990–2000 period to 0.67% in the 2000–2006 period. The overall regional annual rate of deforestation has fallen from 0.33% to 0.28% from the 1990s to 2000s. A high proportion of the spatial variability in forest cover change cannot be explained statistically. However analysis using spline based general additive models detected underlying relationships between forest cover and income or population density of a form consistent with the EKC. The incipient forest transition has not, as yet, resulted in widespread reforestation. Forest recovery remains below 0.20% per year. Reforestation is mostly the result of passive processes associated with reductions in the intensity of land use. Deforestation continues to occur at high rates in some focal areas. A transition could be accelerated if there were a broader recognition among policy makers that the regional rate of forest loss has now begun to fall. The changing trajectory provides an opportunity to actively restore forest cover through stimulating afforestation and stimulating more sustainable land use practices. The results have clear implications for policy aimed at carbon sequestration through reducing

  10. Evidence of incipient forest transition in Southern Mexico.

    Science.gov (United States)

    Vaca, Raúl Abel; Golicher, Duncan John; Cayuela, Luis; Hewson, Jenny; Steininger, Marc

    2012-01-01

    Case studies of land use change have suggested that deforestation across Southern Mexico is accelerating. However, forest transition theory predicts that trajectories of change can be modified by economic factors, leading to spatial and temporal heterogeneity in rates of change that may take the form of the Environmental Kuznets Curve (EKC). This study aimed to assess the evidence regarding potential forest transition in Southern Mexico by classifying regional forest cover change using Landsat imagery from 1990 through to 2006. Patterns of forest cover change were found to be complex and non-linear. When rates of forest loss were averaged over 342 municipalities using mixed-effects modelling the results showed a significant (p<0.001) overall reduction of the mean rate of forest loss from 0.85% per year in the 1990-2000 period to 0.67% in the 2000-2006 period. The overall regional annual rate of deforestation has fallen from 0.33% to 0.28% from the 1990s to 2000s. A high proportion of the spatial variability in forest cover change cannot be explained statistically. However analysis using spline based general additive models detected underlying relationships between forest cover and income or population density of a form consistent with the EKC. The incipient forest transition has not, as yet, resulted in widespread reforestation. Forest recovery remains below 0.20% per year. Reforestation is mostly the result of passive processes associated with reductions in the intensity of land use. Deforestation continues to occur at high rates in some focal areas. A transition could be accelerated if there were a broader recognition among policy makers that the regional rate of forest loss has now begun to fall. The changing trajectory provides an opportunity to actively restore forest cover through stimulating afforestation and stimulating more sustainable land use practices. The results have clear implications for policy aimed at carbon sequestration through reducing

  11. Evidence of incipient forest transition in Southern Mexico.

    Directory of Open Access Journals (Sweden)

    Raúl Abel Vaca

    Full Text Available Case studies of land use change have suggested that deforestation across Southern Mexico is accelerating. However, forest transition theory predicts that trajectories of change can be modified by economic factors, leading to spatial and temporal heterogeneity in rates of change that may take the form of the Environmental Kuznets Curve (EKC. This study aimed to assess the evidence regarding potential forest transition in Southern Mexico by classifying regional forest cover change using Landsat imagery from 1990 through to 2006. Patterns of forest cover change were found to be complex and non-linear. When rates of forest loss were averaged over 342 municipalities using mixed-effects modelling the results showed a significant (p<0.001 overall reduction of the mean rate of forest loss from 0.85% per year in the 1990-2000 period to 0.67% in the 2000-2006 period. The overall regional annual rate of deforestation has fallen from 0.33% to 0.28% from the 1990s to 2000s. A high proportion of the spatial variability in forest cover change cannot be explained statistically. However analysis using spline based general additive models detected underlying relationships between forest cover and income or population density of a form consistent with the EKC. The incipient forest transition has not, as yet, resulted in widespread reforestation. Forest recovery remains below 0.20% per year. Reforestation is mostly the result of passive processes associated with reductions in the intensity of land use. Deforestation continues to occur at high rates in some focal areas. A transition could be accelerated if there were a broader recognition among policy makers that the regional rate of forest loss has now begun to fall. The changing trajectory provides an opportunity to actively restore forest cover through stimulating afforestation and stimulating more sustainable land use practices. The results have clear implications for policy aimed at carbon sequestration through

  12. Iatrogenic Opioid Withdrawal in Critically Ill Patients: A Review of Assessment Tools and Management.

    Science.gov (United States)

    Chiu, Ada W; Contreras, Sofia; Mehta, Sangeeta; Korman, Jennifer; Perreault, Marc M; Williamson, David R; Burry, Lisa D

    2017-12-01

    To (1) provide an overview of the epidemiology, clinical presentation, and risk factors of iatrogenic opioid withdrawal in critically ill patients and (2) conduct a literature review of assessment and management of iatrogenic opioid withdrawal in critically ill patients. We searched MEDLINE (1946-June 2017), EMBASE (1974-June 2017), and CINAHL (1982-June 2017) with the terms opioid withdrawal, opioid, opiate, critical care, critically ill, assessment tool, scale, taper, weaning, and management. Reference list of identified literature was searched for additional references as well as www.clinicaltrials.gov . We restricted articles to those in English and dealing with humans. We identified 2 validated pediatric critically ill opioid withdrawal assessment tools: (1) Withdrawal Assessment Tool-Version 1 (WAT-1) and (2) Sophia Observation Withdrawal Symptoms Scale (SOS). Neither tool differentiated between opioid and benzodiazepine withdrawal. WAT-1 was evaluated in critically ill adults but not found to be valid. No other adult tool was identified. For management, we identified 5 randomized controlled trials, 2 prospective studies, and 2 systematic reviews. Most studies were small and only 2 studies utilized a validated assessment tool. Enteral methadone, α-2 agonists, and protocolized weaning were studied. We identified 2 validated assessment tools for pediatric intensive care unit patients; no valid tool for adults. Management strategies tested in small trials included methadone, α-2 agonists, and protocolized sedation/weaning. We challenge researchers to create validated tools assessing specifically for opioid withdrawal in critically ill children and adults to direct management.

  13. Sedatives for opiate withdrawal in newborn infants.

    Science.gov (United States)

    Osborn, David A; Jeffery, Heather E; Cole, Michael J

    2010-10-06

    Neonatal abstinence syndrome (NAS) due to opiate withdrawal may result in disruption of the mother-infant relationship, sleep-wake abnormalities, feeding difficulties, weight loss and seizures. Treatments used to ameliorate symptoms and reduce morbidity include opiates, sedatives and non-pharmacological treatments. To assess the effectiveness and safety of using a sedative compared to a non-opiate control for NAS due to withdrawal from opiates, and to determine which type of sedative is most effective and safe. This update included searches of the Cochrane Central Register of Controlled Trials (Issue 1, 2010), MEDLINE 1966 to April 2010 and abstracts of conference proceedings. Trials enrolling infants with NAS born to mothers with an opiate dependence with > 80% follow-up and using random or quasi-random allocation to sedative or control. Control could include another sedative or non-pharmacological treatment. Each author assessed study quality and extracted data independently. Seven studies enrolling 385 patients were included. There were substantial methodological concerns for most studies including the use of quasi-random allocation methods and sizeable, largely unexplained differences in reported numbers allocated to each group.One study reported phenobarbitone compared to supportive care alone did not reduce treatment failure or time to regain birthweight, but resulted in a significant reduction in duration of supportive care (MD -162.1 min/day, 95% CI -249.2, -75.1). Comparing phenobarbitone to diazepam, meta-analysis of two studies found phenobarbitone resulted in a significant reduction in treatment failure (typical RR 0.39, 95% CI 0.24, 0.62). Comparing phenobarbitone with chlorpromazine, one study reported no significant difference in treatment failure.In infants treated with an opiate, one study reported addition of clonidine resulted in no significant difference in treatment failure, seizures or mortality. In infants treated with an opiate, one study

  14. Recent advances in alcohol withdrawal states.

    Science.gov (United States)

    Fialkov, M J

    1977-11-26

    Recent advances in alcohol withdrawal states are described. New concepts of classification, the development of the syndrome and its management are outlined. In the light of recent research, more optimistic results for this much maligned but common condition may be achieved.

  15. Mapping socio-environmentally vulnerable populations access and exposure to ecosystem services at the U.S.-Mexico borderlands

    Science.gov (United States)

    Norman, Laura M.; Villarreal, Miguel L.; Lara-Valencia, Francisco; Yuan, Yongping; Nie, Wenming; Wilson, Sylvia; Amaya, Gladys; Sleeter, Rachel

    2012-01-01

    Socio-environmental vulnerable populations are often unrepresented in land-use planning yet have great potential for loss when exposed to changes in ecosystem services. Administrative boundaries, cultural differences, and language barriers increase the disassociation between land-use management and marginalized populations living in the U.S.–Mexico borderlands. This paper describes the development of a Modified Socio-Environmental Vulnerability Index (M-SEVI), using determinants from binational census and neighborhood data that describe levels of education, access to resources, migratory status, housing, and number of dependents, to provide a simplified snapshot of the region's populace that can be used in binational planning efforts. We apply this index at the SCW, located on the border between Arizona, USA and Sonora, Mexico. For comparison, the Soil and Water Assessment Tool is concurrently applied to assess the provision of erosion- and flood control services over a 9-year period. We describe how this coupling of data can form the base for an ecosystem services assessment across political boundaries that can be used by land-use planners. Results reveal potential disparities in environmental risks and burdens throughout the binational watershed in residential districts surrounding and between urban centers. The M-SEVI can be used as an important first step in addressing environmental justice for binational decision-making.

  16. Effect of inclusion levels and withdrawal periods of Tetracin® on ...

    African Journals Online (AJOL)

    ... when withdrawal time was not observed. The study showed that strict adherence to label dosage and withdrawal time should be followed to mitigate the presence of feed grade antibiotic residues in broiler meat among the consuming public. Keywords: Tetracin®; Growth; Carcass; Primal cuts; Organs; Residue; Broiler ...

  17. Dexmedetomidine infusion to facilitate opioid detoxification and withdrawal in a patient with chronic opioid abuse

    Directory of Open Access Journals (Sweden)

    Surjya Prasad Upadhyay

    2011-01-01

    Full Text Available Many patients are admitted to the intensive care unit (ICU for acute intoxication, serious complication of overdose, or withdrawal symptoms of illicit drugs. An acute withdrawal of drugs with addiction potential is associated with a sympathetic overactivity leading to marked psychomimetic disturbances. Acute intoxication or withdrawal of such drugs is often associated with life-threatening complications which require ICU admission and necessitate prolonged sedative analgesic medications, weaning from which is often complicated by withdrawal and other psychomimetic symptoms. Dexmedetomidine, an alpha-2 (α2 agonist, has been used successfully to facilitate withdrawal and detoxification of various drugs and also to control delirium in ICU patients. Herein, we report a case of a chronic opioid abuse (heroin patient admitted with acute overdose complications leading to a prolonged ICU course requiring sedative-analgesic medication; the drug withdrawal-related symptoms further complicated the weaning process. Dexmedetomidine infusion was successfully used as a sedative-analgesic to control the withdrawal-related psychomimetic symptoms and to facilitate smooth detoxification and weaning from opioid and other sedatives.

  18. UMTRA project water sampling and analysis plan -- Shiprock, New Mexico

    International Nuclear Information System (INIS)

    1994-02-01

    Water sampling and analysis plan (WSAP) is required for each U.S. Department of Energy (DOE) Uranium Mill Tailings Remedial Action (UMTRA) Project site to provide a basis for ground water and surface water sampling at disposal and former processing sites. This WSAP identifies and justifies the sampling locations, analytical parameters, detection limits, and sampling frequency for the monitoring stations at the Navaho Reservation in Shiprock, New Mexico, UMTRA Project site. The purposes of the water sampling at Shiprock for fiscal year (FY) 1994 are to (1) collect water quality data at new monitoring locations in order to build a defensible statistical data base, (2) monitor plume movement on the terrace and floodplain, and (3) monitor the impact of alluvial ground water discharge into the San Juan River. The third activity is important because the community of Shiprock withdraws water from the San Juan River directly across from the contaminated alluvial floodplain below the abandoned uranium mill tailings processing site

  19. Land cover mapping of Greater Mesoamerica using MODIS data

    Science.gov (United States)

    Giri, Chandra; Jenkins, Clinton N.

    2005-01-01

    A new land cover database of Greater Mesoamerica has been prepared using moderate resolution imaging spectroradiometer (MODIS, 500 m resolution) satellite data. Daily surface reflectance MODIS data and a suite of ancillary data were used in preparing the database by employing a decision tree classification approach. The new land cover data are an improvement over traditional advanced very high resolution radiometer (AVHRR) based land cover data in terms of both spatial and thematic details. The dominant land cover type in Greater Mesoamerica is forest (39%), followed by shrubland (30%) and cropland (22%). Country analysis shows forest as the dominant land cover type in Belize (62%), Cost Rica (52%), Guatemala (53%), Honduras (56%), Nicaragua (53%), and Panama (48%), cropland as the dominant land cover type in El Salvador (60.5%), and shrubland as the dominant land cover type in Mexico (37%). A three-step approach was used to assess the quality of the classified land cover data: (i) qualitative assessment provided good insight in identifying and correcting gross errors; (ii) correlation analysis of MODIS- and Landsat-derived land cover data revealed strong positive association for forest (r2 = 0.88), shrubland (r2 = 0.75), and cropland (r2 = 0.97) but weak positive association for grassland (r2 = 0.26); and (iii) an error matrix generated using unseen training data provided an overall accuracy of 77.3% with a Kappa coefficient of 0.73608. Overall, MODIS 500 m data and the methodology used were found to be quite useful for broad-scale land cover mapping of Greater Mesoamerica.

  20. 75 FR 32962 - Notice of Intent To Prepare a Resource Management Plan for the Carlsbad Field Office, New Mexico...

    Science.gov (United States)

    2010-06-10

    ... To Prepare a Resource Management Plan for the Carlsbad Field Office, New Mexico and Associated Environmental Impact Statement AGENCY: Bureau of Land Management, Interior. ACTION: Notice of Intent. SUMMARY... associated Environmental Impact Statement (EIS) for the Carlsbad Field Office and by this notice is...

  1. Stories of Hell and Healing: Internet Users’ Construction of Benzodiazepine Distress and Withdrawal

    OpenAIRE

    Fixsen, Alison; Ridge, Damien T.

    2017-01-01

    Abstract Benzodiazepines are a group of drugs used mainly as sedatives, hypnotics, antiepileptics, and muscle relaxants. Consumption is recommended for 2 to 4 weeks only, due to fast onset of dependency and potentially distressing withdrawal symptoms. Few peer-review studies have drawn on the user experiences and language to appreciate firsthand experiences of benzodiazepine withdrawal or discontinuation syndrome. We looked extensively at patient stories of benzodiazepine withdrawal and recov...

  2. An exploratory study of cannabis withdrawal among Indigenous Australian prison inmates: study protocol.

    Science.gov (United States)

    Rogerson, Bernadette; Copeland, Jan; Buttner, Petra; Bohanna, India; Cadet-James, Yvonne; Sarnyai, Zoltan; Clough, Alan R

    2013-05-28

    Cannabis use and dependence is a serious health and criminal justice issue among incarcerated populations internationally. Upon abrupt, enforced cessation of cannabis, prisoners may suffer irritability and anger that can lead to threatening behaviour, intimidation, violence, sleep disturbances and self-harm. Cannabis withdrawal syndrome, proposed for inclusion in the Diagnostic and Statistical Manual of Mental Disorders in 2013, has not been examined in Indigenous populations. Owing to the exceptionally high rates of cannabis use in the community, high proportions of Australian Indigenous prisoners may suffer from withdrawal upon entry to custody. 60 male and 60 female Indigenous prisoners (18-40 years) at a high risk of cannabis dependence will be recruited upon entry to custody. A pictorial representation of the standard Cannabis Withdrawal Scale will be tested for reliability and validity. Cortisol markers will be measured in saliva, as the indicators of onset and severity of cannabis withdrawal and psychological distress. The characteristics will be described as percentages and mean or median values with 95% CI. Receiver operator curve analysis will determine an ideal cut-off of the Cannabis Withdrawal Scale and generalised estimating equations modelling will test changes over time. The acceptability and efficacy of proposed resources will be assessed qualitatively using thematic analysis. A valid and reliable measure of cannabis withdrawal for use with Indigenous populations, the onset and time course of withdrawal symptoms in this population and the development of culturally acceptable resources and interventions to identify and manage cannabis withdrawal. The project has been approved by the James Cook University Human Research Ethics Committee (approval number H4651).The results will be reported via peer reviewed publications, conference, seminar presentations and on-line media for national and international dissemination.

  3. Methadone Management of Withdrawal Associated With Loperamide-related Opioid Use Disorder.

    Science.gov (United States)

    Leo, Raphael J; Ghazi, Muhammad A; Jaziri, Kelly S

    : Loperamide hydrochloride is an over-the-counter anti-diarrheal agent, acting via mu-opioid receptor agonist effects in the intestinal myenteric plexus. Although preclinical investigations suggested that abuse liability associated with loperamide use is low, there are increasing numbers of cases reported to the US Food and Drug Administration, of abuse, dependence, and withdrawal associated with loperamide use. A case of a patient with opioid use disorder, that is, in the form of protracted loperamide excess use, requiring management of withdrawal with methadone is presented. Management of withdrawal from abrupt loperamide discontinuation has not been discussed in the literature. Long-term treatment issues are also described.

  4. Remifentanil Prevents Withdrawal Movements Caused by Intravenous Injection of Rocuronium

    Science.gov (United States)

    Choi, Byung In; Choi, Seung Ho; Shin, Yang-Sik; Lee, Sung Jin; Yoon, Kyung Bong; Shin, Seo Kyung

    2008-01-01

    Purpose The incidence of pain induced withdrawal movement following intravenous injection of rocuronium is high. This randomized, double-blind, placebo-controlled study was designed to evaluate the effect of pretreatment of remifentanil on the withdrawal movements due to intravenous injection of rocuronium during anesthetic induction. Materials and Methods Ninety adult female patients undergoing thyroidectomy were randomly allocated to three groups. Each patient intravenously received one of three solutions of equal volume (4 mL): normal saline (Group I, n = 30), 0.5 µg/kg remifentanil (Group II, n = 30) or 1 µg/kg remifentanil (Group III, n = 30). Thirty seconds after remifentanil administration, anesthesia was induced with 5 mg/kg IV thiopental. Twenty seconds after thiopental injection, 0.6 mg/kg IV rocuronium was administered (injection rate of 0.5 mL/sec) and patients' withdrawal movements were assessed. Mean arterial pressure (MAP) and heart rate were assessed on arrival in the operation room, before the tracheal intubation and immediately, 1 and 2 min after the tracheal intubation. Results The incidence of withdrawal movements was significantly lower in both of the remifentanil groups (3 and 0% in Group II and III, respectively) than in the saline group (70%). Remifentanil attenuated the increase of heart rate and MAP immediately and 1 min after the tracheal intubation. Conclusion The pretreatment with 0.5 and 1.0 µg/kg remifentanil of bolus doses prevented the withdrawal movements caused by rocuronium injection, and effectively blunted cardiovascular activation following tracheal intubation. PMID:18452256

  5. Paying Attention to and Not Neglecting Social Withdrawal and Social Isolation

    Science.gov (United States)

    Rubin, Kenneth H.; Coplan, Robert J.

    2004-01-01

    This commentary outlines the origins, history, and current status of research related to children's social withdrawal and social isolation. Early research related to children's peer relationships is first explored, followed by a discussion of the relative "neglect" of social withdrawal prior to the 1980s. Increased research attention since that…

  6. Extubation versus tracheostomy in withdrawal of treatment-ethical, clinical, and legal perspectives.

    LENUS (Irish Health Repository)

    Chotirmall, Sanjay Haresh

    2010-06-01

    The provision of life-sustaining ventilation, such as tracheostomy to critically ill patients, is commonly performed. However, the utilization of tracheostomy or extubation after a withdrawal of treatment decision is debated. There is a dearth of practical information available to aid clinical decision making because withdrawal of treatment is a challenging scenario for all concerned. This is further complicated by medicolegal and ethical considerations. Care of the "hopelessly ill" patient should be based on daily evaluation and comfort making it impossible to fit into general algorithms. Although respect for autonomy is important in healthcare, it is limited for patients in an unconscious state. Beneficence remains the basis for withdrawing treatment in futile cases and underpins the "doctrine of double effect." This article presents a relevant clinical case of hypoxic brain injury where a question of withdrawal of treatment arose and examines the ethical, clinical, and medicolegal considerations inherent in such cases, including beneficence, nonmaleficence, and the "sanctity of life doctrine." In addition, the considerations of prognosis for recovery, patient autonomy, patient quality of life, and patient family involvement, which are central to decision making, are addressed. The varying legal frameworks that exist internationally regarding treatment withdrawal are also described. Good ethics needs sound facts, and despite the lack of legal foundation in several countries, withdrawal of treatment remains practiced, and the principles described within this article aim to aid clinician decision making during such complex and multifaceted end-of-life decisions.

  7. Cerebral blood flow and oxygen consumption during ethanol withdrawal in the rat.

    Science.gov (United States)

    Hemmingsen, R; Barry, D I; Hertz, M M; Klinken, L

    1979-09-14

    The ethanol withdrawal syndrome in man and animals is characterized by signs of CNS hyperactivity although a direct measurement of a physiological variable reflecting this CNS hyperactivity has never been performed in untreated man or in animals. We induced ethanol dependence in the rat by means of intragastric intubation with a 20% w/v ethanol solution, thus keeping the animals in a state of continuous severe intoxication for 3--4 days; during the subsequent state of withdrawal characterized by tremor, rigidity, stereotyped movements and general seizures a 25% increase in cerebral oxygen consumption (CMRO2) could be measured; this increase was not due to catecholamines originating from adrenal medulla as adrenomedullectomized animals showed a similar increase in CMRO2 (28%); the withdrawing animals showed a corresponding cerebral blood flow (CBF) increase. The elevated CMRO2 and CBF could be reduced to normal by administration of a beta-adrenergic receptor blocker (propranolol 2 mg/kg i.v.), and hence the increased CMRO2 during ethanol withdrawal could be related to catecholaminergic systems in the brain, e.g. the noradrenergic locus coeruleus system which is anatomically well suited as a general activating system. This interpretation is supported by the earlier neurochemical finding of an increased cerebral noradrenaline turnover during ethanol withdrawal. The exact mechanism underlying the increased cerebral oxygen consumption during ethanol withdrawal and the effect of propranolol on cerebral function during this condition remains to be clarified.

  8. Modulation of histone deacetylase attenuates naloxone-precipitated opioid withdrawal syndrome.

    Science.gov (United States)

    Rehni, Ashish K; Singh, Nirmal; Rachamalla, Mahesh; Tikoo, Kulbhushan

    2012-06-01

    The present study has been designed to investigate the effect of selective inhibitors of histone deacetylase and/or N-acetyl-Asp-Glu-Val-Asp-al (Ac-DEVD-CHO), a selective interleukin-1β converting enzyme inhibitor, on the development of naloxone-induced opioid withdrawal syndrome both in vitro and in vivo and the effect of histone deacetylase inhibition on histone H3 acetylation in brain. Sub-acute morphine administration followed by a single injection of naloxone (8 mg/kg, i.p.) was used to precipitate opioid withdrawal syndrome in mice. Behavioral observations were made immediately after naloxone treatment. Withdrawal syndrome was quantitatively assessed in terms of withdrawal severity score and frequency of jumping, rearing, fore paw licking and circling. Separately naloxone-induced contraction in morphine-dependent isolated rat ileum was employed as an in vitro model. An isobolographic study design was employed to assess potential synergistic activity between trichostatin A and Ac-DEVD-CHO. Brain histone acetylation status was examined by western blotting. Injection of naloxone precipitated a severe form of abstinence syndrome in morphine-dependent mice along with strong contracture in isolated rat ileum. Administration of tributyrin (1.5, 3 and 6 g/kg, p.o.), trichostatin A (0.3, 1.0 and 3.0 mg/kg, p.o.) and Ac-DEVD-CHO (0.3, 1.0 and 3.0 mg/kg, p.o.) markedly and dose dependently attenuated naloxone-induced morphine withdrawal syndrome in vivo as well as in vitro in rat ileum. Trichostatin A was also observed to exert a synergistic interaction with Ac-DEVD-CHO. Western blot analysis revealed that multiple administration with the effective dose of tributyrin or trichostatin A in the in vivo experiments induced hyperacetylation of histone H3 in the mouse brain. Thus, it is proposed that histone deacetylase activation linked mechanism might be involved in the development of opioid dependence and the precipitation of its withdrawal syndrome.

  9. Cannabis Withdrawal Among Detained Adolescents: Exploring the Impact of Nicotine and Race.

    Science.gov (United States)

    Soenksen, Shayna; Stein, L A R; Brown, Joanna D; Stengel, JoAnn R; Rossi, Joseph S; Lebeau, Rebecca

    2015-04-01

    Rates of marijuana use among detained youths are exceptionally high. Research suggests a cannabis withdrawal syndrome is valid and clinically significant; however, these studies have mostly been conducted in highly controlled laboratory settings with treatment-seeking, White adults. The present study analyzed archival data to explore the magnitude of cannabis withdrawal symptoms within a diverse sample of detained adolescents while controlling for tobacco use and investigating the impact of race on symptom reports. Adolescents recruited from a juvenile correctional facility (N=93) completed a background questionnaire and the Marijuana Withdrawal Checklist. Analyses revealed a significant main effect for level of tobacco use on severity of irritability, and for level of marijuana use on severity of craving to smoke marijuana and strange/wild dreams. Furthermore, a significant main effect for race was found with Black adolescents reporting lower withdrawal discomfort scores and experiencing less severe depressed mood, difficulty sleeping, nervousness/anxiety, and strange/wild dreams. Although exploratory, these findings may have significant clinical implications for providers in juvenile detention facilities, allowing the execution of proper medical and/or behavioral interventions to assist adolescents presenting with problematic cannabis and/or tobacco withdrawal.

  10. Closing the loop: integrating human impacts on water resources to advanced land surface models

    Science.gov (United States)

    Zaitchik, B. F.; Nie, W.; Rodell, M.; Kumar, S.; Li, B.

    2016-12-01

    Advanced Land Surface Models (LSMs), including those used in the North American Land Data Assimilation System (NLDAS), offer a physically consistent and spatially and temporally complete analysis of the distributed water balance. These models are constrained both by physically-based process representation and by observations ingested as meteorological forcing or as data assimilation updates. As such, they have become important tools for hydrological monitoring and long-term climate analysis. The representation of water management, however, is extremely limited in these models. Recent advances have brought prognostic irrigation routines into models used in NLDAS, while assimilation of Gravity Recovery and Climate Experiment (GRACE) derived estimates of terrestrial water storage anomaly has made it possible to nudge models towards observed states in water storage below the root zone. But with few exceptions these LSMs do not account for the source of irrigation water, leading to a disconnect between the simulated water balance and the observed human impact on water resources. This inconsistency is unacceptable for long-term studies of climate change and human impact on water resources in North America. Here we define the modeling challenge, review instances of models that have begun to account for water withdrawals (e.g., CLM), and present ongoing efforts to improve representation of human impacts on water storage across models through integration of irrigation routines, water withdrawal information, and GRACE Data Assimilation in NLDAS LSMs.

  11. Withdrawal of repeated morphine enhances histamine-induced scratching responses in mice.

    Science.gov (United States)

    Abe, Kenji; Kobayashi, Kanayo; Yoshino, Saori; Taguchi, Kyoji; Nojima, Hiroshi

    2015-04-01

    An itch is experientially well known that the scratching response of conditions such as atopic dermatitis is enhanced under psychological stress. Morphine is typical narcotic drug that induces a scratching response upon local application as an adverse drug reaction. Although long-term treatment with morphine will cause tolerance and dependence, morphine withdrawal can cause psychologically and physiologically stressful changes in humans. In this study, we evaluated the effects of morphine withdrawal on histamine-induced scratching behavior in mice. Administration of morphine with progressively increasing doses (10-50 mg/kg, i.p.) was performed for 5 consecutive days. At 3, 24, 48, and 72 hr after spontaneous withdrawal from the final morphine dose, histamine was intradermally injected into the rostral part of the back and then the number of bouts of scratching in 60 min was recorded and summed. We found that at 24 hr after morphine withdrawal there was a significant increase in histamine-induced scratching behavior. The spinal c-Fos positive cells were also significantly increased. The relative adrenal weight increased and the relative thymus weight decreased, both significantly. Moreover, the plasma corticosterone levels changed in parallel with the number of scratching bouts. These results suggest that morphine withdrawal induces a stressed state and enhances in histamine-induced scratching behavior. Increased reaction against histamine in the cervical vertebrae will participate in this stress-induced itch enhancement.

  12. Aggression and increased glutamate in the mPFC during withdrawal from intermittent alcohol in outbred mice.

    Science.gov (United States)

    Hwa, Lara S; Nathanson, Anna J; Shimamoto, Akiko; Tayeh, Jillian K; Wilens, Allison R; Holly, Elizabeth N; Newman, Emily L; DeBold, Joseph F; Miczek, Klaus A

    2015-08-01

    Disrupted social behavior, including occasional aggressive outbursts, is characteristic of withdrawal from long-term alcohol (EtOH) use. Heavy EtOH use and exaggerated responses during withdrawal may be treated using glutamatergic N-methyl-D-aspartate receptor (NMDAR) antagonists. The current experiments explore aggression and medial prefrontal cortex (mPFC) glutamate as consequences of withdrawal from intermittent access to EtOH and changes in aggression and mPFC glutamate caused by NMDAR antagonists memantine and ketamine. Swiss male mice underwent withdrawal following 1-8 weeks of intermittent access to 20 % EtOH. Aggressive and nonaggressive behaviors with a conspecific were measured 6-8 h into EtOH withdrawal after memantine or ketamine (0-30 mg/kg, i.p.) administration. In separate mice, extracellular mPFC glutamate after memantine was measured during withdrawal using in vivo microdialysis. At 6-8 h withdrawal from EtOH, mice exhibited more convulsions and aggression and decreased social contact compared to age-matched water controls. Memantine, but not ketamine, increased withdrawal aggression at the 5-mg/kg dose in mice with a history of 8 weeks of EtOH but not 1 or 4 weeks of EtOH or in water drinkers. Tonic mPFC glutamate was higher during withdrawal after 8 weeks of EtOH compared to 1 week of EtOH or 8 weeks of water. Five milligrams per kilogram of memantine increased glutamate in 8-week EtOH mice, but also in 1-week EtOH and water drinkers. These studies reveal aggressive behavior as a novel symptom of EtOH withdrawal in outbred mice and confirm a role of NMDARs during withdrawal aggression and for disrupted social behavior.

  13. Apollo 11 crew on ship during water egress training in Gulf of Mexico

    Science.gov (United States)

    1969-01-01

    The prime crew of the Apollo 11 lunar landing mission relaxes on the deck of the NASA Motor Vessel Retriever prior to participating in water egress training in the Gulf of Mexico. Left to right, are Astronauts Edwin A. Aldrin Jr., lunar module pilot; Neil A. Armstrong, commander; and Michael Collins, command module pilot. In the background is Apollo Boilerplate 1102 which was used in the training exercise.

  14. Optimizing withdrawal from drinking water reservoirs to reduce downstream temperature pollution and reservoir hypoxia.

    Science.gov (United States)

    Weber, M; Rinke, K; Hipsey, M R; Boehrer, B

    2017-07-15

    Sustainable management of drinking water reservoirs requires balancing the demands of water supply whilst minimizing environmental impact. This study numerically simulates the effect of an improved withdrawal scheme designed to alleviate the temperature pollution downstream of a reservoir. The aim was to identify an optimal withdrawal strategy such that water of a desirable discharge temperature can be supplied downstream without leading to unacceptably low oxygen concentrations within the reservoir. First, we calibrated a one-dimensional numerical model for hydrodynamics and oxygen dynamics (GLM-AED2), verifying that the model reproduced water temperatures and hypolimnetic dissolved oxygen concentrations accurately over a 5 year period. Second, the model was extended to include an adaptive withdrawal functionality, allowing for a prescribed withdrawal temperature to be found, with the potential constraint of hypolimnetic oxygen concentration. Scenario simulations on epi-/metalimnetic withdrawal demonstrate that the model is able to autonomously determine the best withdrawal height depending on the thermal structure and the hypolimnetic oxygen concentration thereby optimizing the ability to supply a desirable discharge temperature to the downstream river during summer. This new withdrawal strategy also increased the hypolimnetic raw water volume to be used for drinking water supply, but reduced the dissolved oxygen concentrations in the deep and cold water layers (hypolimnion). Implications of the results for reservoir management are discussed and the numerical model is provided for operators as a simple and efficient tool for optimizing the withdrawal strategy within different reservoir contexts. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. Complementing the Numbers: A Text Mining Analysis of College Course Withdrawals

    Science.gov (United States)

    Michalski, Greg V.

    2011-01-01

    Excessive college course withdrawals are costly to the student and the institution in terms of time to degree completion, available classroom space, and other resources. Although generally well quantified, detailed analysis of the reasons given by students for course withdrawal is less common. To address this, a text mining analysis was performed…

  16. The Combination Very Low-Dose Naltrexone–Clonidine in the Management of Opioid Withdrawal

    Science.gov (United States)

    Mannelli, Paolo; Peindl, Kathleen; Wu, Li-Tzy; Patkar, Ashwin A.; Gorelick, David A.

    2013-01-01

    Background The management of withdrawal absorbs substantial clinical efforts in opioid dependence (OD). The real challenge lies in improving current pharmacotherapies. Although widely used, clonidine causes problematic adverse effects and does not alleviate important symptoms of opioid withdrawal, alone or in combination with the opioid antagonist naltrexone. Very low-dose naltrexone (VLNTX) has been shown to attenuate withdrawal intensity and noradrenaline release following opioid agonist taper, suggesting a combination with clonidine may result in improved safety and efficacy. Objectives We investigated the effects of a VLNTX–clonidine combination in a secondary analysis of data from a double-blind, randomized opioid detoxification trial. Methods Withdrawal symptoms and treatment completion were compared following VLNTX (.125 or .25 mg/day) and clonidine (.1–.2 mg q6h) in 127 individuals with OD undergoing 6-day methadone inpatient taper at a community program. Results VLNTX was more effective than placebo or clonidine in reducing symptoms and signs of withdrawal. The use of VLNTX in combination with clonidine was associated with attenuated subjective withdrawal compared with each medication alone, favoring detoxification completion in comparison with clonidine or naltrexone placebo. VLNTX/clonidine was effective in reducing symptoms that are both undertreated and well controlled with clonidine treatment and was not associated with significant adverse events compared with other treatments. Conclusions and Scientific Significance Preliminary results elucidate neurobiological mechanisms of OD and support the utility of controlled studies on a novel VLNTX + low-dose clonidine combination for the management of opioid withdrawal. PMID:22233189

  17. Mapping vegetation and fuels for fire management on the Gila National Forest Complex, New Mexico

    Science.gov (United States)

    Robert E. Keane; Scott A. Mincemoyer; Kirsten M. Schmidt; Donald G. Long; Janice L. Garner

    2000-01-01

    (Please note: This PDF is part of a CD-ROM package only and was not printed on paper.) Fuels and vegetation spatial data layers required by the spatially explicit fire growth model FARSITE were developed for all lands in and around the Gila National Forest in New Mexico. Satellite imagery, terrain modeling, and biophysical simulation were used to create the three...

  18. Efficacy of extended-release tramadol for treatment of prescription opioid withdrawal: A two-phase randomized controlled trial*

    Science.gov (United States)

    Lofwall, Michelle R.; Babalonis, Shanna; Nuzzo, Paul A.; Siegel, Anthony; Campbell, Charles; Walsh, Sharon L.

    2013-01-01

    Background Tramadol is an atypical analgesic with monoamine and modest mu opioid agonist activity. The purpose of this study was to evaluate: 1) the efficacy of extended-release (ER) tramadol in treating prescription opioid withdrawal and 2) whether cessation of ER tramadol produces opioid withdrawal. Methods Prescription opioid users with current opioid dependence and observed withdrawal participated in this inpatient, two-phase double blind, randomized placebo-controlled trial. In Phase 1 (days 1-7), participants were randomly assigned to matched oral placebo or ER tramadol (200 or 600 mg daily). In Phase 2 (days 8-13), all participants underwent double blind crossover to placebo. Breakthrough withdrawal medications were available for all subjects. Enrollment continued until 12 completers/group was achieved. Results Use of breakthrough withdrawal medication differed significantly (popioid withdrawal. Mild opioid withdrawal occurred after cessation of treatment with 600 mg tramadol. These data support the continued investigation of tramadol as a treatment for opioid withdrawal. PMID:23755929

  19. Efficacy of extended-release tramadol for treatment of prescription opioid withdrawal: a two-phase randomized controlled trial.

    Science.gov (United States)

    Lofwall, Michelle R; Babalonis, Shanna; Nuzzo, Paul A; Siegel, Anthony; Campbell, Charles; Walsh, Sharon L

    2013-11-01

    Tramadol is an atypical analgesic with monoamine and modest mu opioid agonist activity. The purpose of this study was to evaluate: (1) the efficacy of extended-release (ER) tramadol in treating prescription opioid withdrawal and (2) whether cessation of ER tramadol produces opioid withdrawal. Prescription opioid users with current opioid dependence and observed withdrawal participated in this inpatient, two-phase double blind, randomized placebo-controlled trial. In Phase 1 (days 1-7), participants were randomly assigned to matched oral placebo or ER tramadol (200 or 600 mg daily). In Phase 2 (days 8-13), all participants underwent double blind crossover to placebo. Breakthrough withdrawal medications were available for all subjects. Enrollment continued until 12 completers/group was achieved. Use of breakthrough withdrawal medication differed significantly (popioid withdrawal. Mild opioid withdrawal occurred after cessation of treatment with 600 mg tramadol. These data support the continued investigation of tramadol as a treatment for opioid withdrawal. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

  20. Adaptation to the degradation of natural resources in the semiarid area of Mexico

    Directory of Open Access Journals (Sweden)

    José Luis Gonzalez Barrios

    2010-12-01

    Full Text Available Hydrology and soil research in the semiarid zone of Mexico highlight an erosion process that is worsened by climate and land use changes. Scientific results have inspired a successful adaptation program with an environmental and socioeconomic scope. The Hydrological Environmental Services Programm.e (PSAH, in Spanish pays local workers to build soil and water conservation infrastructure in areas with the potential to provide hydrological environmental services. The programme’s results are still under assessment, but some qualitative results may be already identified: soil and water retention, plant cover recovery, permanence of local people in their comm.unities, and social welfare, among others. The PSAH as a strategy should be echoed in other places of Mexico in order to replicate their benefits on the physical and human environments of the semiarid zone.

  1. Effects of water use and land use on streamflow and aquatic habitat in the Sudbury and Assabet River Basins, Massachusetts

    Science.gov (United States)

    Zarriello, Phillip J.; Parker, Gene W.; Armstrong, David S.; Carlson, Carl S.

    2010-01-01

    Water withdrawals from surface-water reservoirs and groundwater have affected streamflow in the Sudbury and Assabet River Basins. These effects are particularly evident in the upper Sudbury River Basin, which prompted the need to improve the understanding of water resources and aquatic habitat in these basins. In 2004, the U.S. Geological Survey, in cooperation with the Massachusetts Department of Conservation and Recreation, developed a precipitation-runoff model that uses Hydrologic Simulation Program-FORTRAN (HSPF) to evaluate the effects of water use and projected future water-use and land-use change on streamflow. As part of this study, the aquatic habitat in the basins and the effects of streamflow alteration also were evaluated. Chapter 1 of the report covers the development of the HSPF model that focuses on the upper Sudbury River Basin (106 square miles) but covers the entire Sudbury and Assabet River Basins (339 square miles). The model was calibrated to an 11-year period (1993-2003) using observed or estimated streamflow at four streamgages. The model was then used to simulate long-term (1960-2004) streamflows to evaluate the effects of average 1993-2003 water use and projected 2030 water-use and land-use change over long-term climatic conditions. Simulations indicate that the average 1993-2003 withdrawals most altered streamflow relative to no withdrawals in small headwater subbasins where the ratios of mean annual withdrawals to mean annual streamflow are the highest. The effects of withdrawals are also appreciable in other parts of the upper Sudbury River Basin as a result of the perpetuation of the effects of large withdrawals in upstream reaches or in subbasins that also have a high ratio of withdrawal to streamflow. The simulated effects of potential 2030 water-use and land-use change indicate small decreases in flows as a result of increased water demands, but these flow alterations were offset as a result of decreased evapotranspiration

  2. Arizona/New Mexico Plateau Ecoregion: Chapter 26 in Status and trends of land change in the Western United States--1973 to 2000

    Science.gov (United States)

    Ruhlman, Jana; Gass, Leila; Middleton, Barry

    2012-01-01

    Situated between ecoregions of distinctly different topographies and climates, the Arizona/New Mexico Plateau Ecoregion represents a large area of approximately 192,869 km2 (74,467 mi2) that stretches across northern Arizona, central and northwestern New Mexico, and parts of southwestern Colorado; in addition, a small part extends into southeastern Nevada (fig. 1) (Omernik, 1987; U.S. Environmental Protection Agency, 1997). Forested, mountainous terrain borders the ecoregion on the northeast (Southern Rockies Ecoregion) and southwest (Arizona/New Mexico Mountains Ecoregion). Warmer and drier climates exist to the south (Chihuahuan Deserts Ecoregion) and west (Mojave Basin and Range Ecoregion). The semiarid grasslands of the western Great Plains are to the east (Southwestern Tablelands Ecoregion), and the tablelands of the Colorado Plateau in Utah and western Colorado lie to the north (Colorado Plateaus Ecoregion). The Arizona/New Mexico Plateau Ecoregion occupies a significant portion of the southern half of the Colorado Plateau.

  3. Long-term surveillance plan for the Shiprock disposal site, Shiprock, New Mexico

    International Nuclear Information System (INIS)

    1993-12-01

    The long-term surveillance plan (LTSP) for the Shiprock, New Mexico, Uranium Mill Tailings Remedial Action (UMTRA) Project disposal site describes the surveillance activities for the Shiprock disposal cell. The US Department of Energy (DOE) will carry out these activities to ensure that the disposal cell continues to function as designed. This final LTSP is being submitted to the US Nuclear Regulatory Commission (NRC) as a requirement for issuance of a general license for custody and long-term care for the disposal site. The general license requires that the disposal cell be cared for in accordance with the provisions of this LTSP. This Shiprock, New Mexico, LTSP documents whether the land and interests are owned by the US or an Indian tribe and describes in detail the long-term care program through the UMTRA Project Office

  4. Effect of Nimodipine on Morphine-related Withdrawal Syndrome in Rat Model: An Observational Study

    Science.gov (United States)

    Mishra, Pravash Ranjan; Barik, Mayadhar; Ray, Subrata Basu

    2017-01-01

    Objective: To observe the effect of L-type calcium channel blocker like nimodipine on morphine's withdrawal when it was administered continuously along with morphine versus a single bolus dose of nimodipine, which was administered at the end of the experiment before the precipitation of withdrawal reaction in morphine-dependent rats. Materials and Methods: Four groups of adult male Wistar rats were rendered morphine dependent by subcutaneous injections of morphine at a dose of 10 mg/kg for 10 days. Nimodipine 10 mg/kg intraperitoneally (ip) administered to one group once daily before morphine administration in the entire experimental period, and another group received nimodipine only once at the end of the experiment as a single bolus dose 2 mg/kg before the administration of naloxone. Naloxone 3 mg/kg was administered ip to all the groups to precipitate withdrawal reactions. The withdrawal reactions were evaluated and scored as per the Gellert and Holtzman global withdrawal rating scale. Results: Nimodipine when administered as a single bolus dose before naloxone administration in morphine-dependant rats reduced the features of withdrawal reactions more effectively than continuous administration of nimodipine along with morphine throughout the experimental period. Conclusion: We discovered that nimodipine helps in attenuating the severity of morphine withdrawal having potential role encountered during pharmacotherapy with morphine management of opioid dependence, well memory, impairement, cell signaling and phosphorylation of neuron. PMID:28553371

  5. Dopamine agonist withdrawal syndrome: implications for patient care.

    Science.gov (United States)

    Nirenberg, Melissa J

    2013-08-01

    Dopamine agonists are effective treatments for a variety of indications, including Parkinson's disease and restless legs syndrome, but may have serious side effects, such as orthostatic hypotension, hallucinations, and impulse control disorders (including pathological gambling, compulsive eating, compulsive shopping/buying, and hypersexuality). The most effective way to alleviate these side effects is to taper or discontinue dopamine agonist therapy. A subset of patients who taper a dopamine agonist, however, develop dopamine agonist withdrawal syndrome (DAWS), which has been defined as a severe, stereotyped cluster of physical and psychological symptoms that correlate with dopamine agonist withdrawal in a dose-dependent manner, cause clinically significant distress or social/occupational dysfunction, are refractory to levodopa and other dopaminergic medications, and cannot be accounted for by other clinical factors. The symptoms of DAWS include anxiety, panic attacks, dysphoria, depression, agitation, irritability, suicidal ideation, fatigue, orthostatic hypotension, nausea, vomiting, diaphoresis, generalized pain, and drug cravings. The severity and prognosis of DAWS is highly variable. While some patients have transient symptoms and make a full recovery, others have a protracted withdrawal syndrome lasting for months to years, and therefore may be unwilling or unable to discontinue DA therapy. Impulse control disorders appear to be a major risk factor for DAWS, and are present in virtually all affected patients. Thus, patients who are unable to discontinue dopamine agonist therapy may experience chronic impulse control disorders. At the current time, there are no known effective treatments for DAWS. For this reason, providers are urged to use dopamine agonists judiciously, warn patients about the risks of DAWS prior to the initiation of dopamine agonist therapy, and follow patients closely for withdrawal symptoms during dopamine agonist taper.

  6. Reconstruction of global gridded monthly sectoral water withdrawals for 1971–2010 and analysis of their spatiotemporal patterns

    Directory of Open Access Journals (Sweden)

    Z. Huang

    2018-04-01

    Full Text Available Human water withdrawal has increasingly altered the global water cycle in past decades, yet our understanding of its driving forces and patterns is limited. Reported historical estimates of sectoral water withdrawals are often sparse and incomplete, mainly restricted to water withdrawal estimates available at annual and country scales, due to a lack of observations at seasonal and local scales. In this study, through collecting and consolidating various sources of reported data and developing spatial and temporal statistical downscaling algorithms, we reconstruct a global monthly gridded (0.5° sectoral water withdrawal dataset for the period 1971–2010, which distinguishes six water use sectors, i.e., irrigation, domestic, electricity generation (cooling of thermal power plants, livestock, mining, and manufacturing. Based on the reconstructed dataset, the spatial and temporal patterns of historical water withdrawal are analyzed. Results show that total global water withdrawal has increased significantly during 1971–2010, mainly driven by the increase in irrigation water withdrawal. Regions with high water withdrawal are those densely populated or with large irrigated cropland production, e.g., the United States (US, eastern China, India, and Europe. Seasonally, irrigation water withdrawal in summer for the major crops contributes a large percentage of total annual irrigation water withdrawal in mid- and high-latitude regions, and the dominant season of irrigation water withdrawal is also different across regions. Domestic water withdrawal is mostly characterized by a summer peak, while water withdrawal for electricity generation has a winter peak in high-latitude regions and a summer peak in low-latitude regions. Despite the overall increasing trend, irrigation in the western US and domestic water withdrawal in western Europe exhibit a decreasing trend. Our results highlight the distinct spatial pattern of human water use by sectors at

  7. 40 CFR 96.286 - Withdrawal from CAIR SO2 Trading Program.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Withdrawal from CAIR SO2 Trading... PROGRAMS (CONTINUED) NOX BUDGET TRADING PROGRAM AND CAIR NOX AND SO2 TRADING PROGRAMS FOR STATE IMPLEMENTATION PLANS CAIR SO2 Opt-in Units § 96.286 Withdrawal from CAIR SO2 Trading Program. Except as provided...

  8. Land subsidence caused by a single water extraction well and rapid water infiltration

    Directory of Open Access Journals (Sweden)

    I. Martinez-Noguez

    2015-11-01

    Full Text Available Nowadays several parts of the world suffer from land subsidence. This setting of the earth surface occurs due to different factors such as earth quakes, mining activities, and gas, oil and water withdrawal. This research presents a numerical study of the influence of land subsidence caused by a single water extraction well and rapid water infiltration into structural soil discontinuities. The numerical simulation of the infiltration was based on a two-phase flow-model for porous media, and for the deformation a Mohr–Coulomb model was used. A two-layered system with a fault zone is presented. First a single water extraction well is simulated producing a cone-shaped (conical water level depletion, which can cause land subsidence. Land Subsidence can be further increased if a hydrological barrier as a result of a discontinuity, exists. After water extraction a water column is applied on the top boundary for one hours in order to represent a strong storm which produces rapid water infiltration through the discontinuity as well as soil deformation. Both events are analysed and compared in order to characterize deformation of both elements and to get a better understanding of the land subsidence and new fracture formations.

  9. Ketogenic Diet Suppresses Alcohol Withdrawal Syndrome in Rats.

    Science.gov (United States)

    Dencker, Ditte; Molander, Anna; Thomsen, Morgane; Schlumberger, Chantal; Wortwein, Gitta; Weikop, Pia; Benveniste, Helene; Volkow, Nora D; Fink-Jensen, Anders

    2018-02-01

    Alcohol use disorder is underdiagnosed and undertreated, and up to 50% of alcohol-abstinent patients diagnosed with alcohol dependence relapse within the first year of treatment. Current treatments for the maintenance of alcohol abstinence in patients with alcohol use disorder have limited efficacy, and there is an urgent need for novel treatment strategies. Decreased cerebral glucose metabolism and increased brain uptake of acetate were recently reported in heavy drinkers, relative to controls. Given the switch of metabolic fuel from glucose to acetate in the alcohol-dependent brain, we investigated the potential therapeutic benefit of a ketogenic diet in managing alcohol withdrawal symptoms during detoxification. Male Sprague Dawley rats fed either ketogenic or regular diet were administered ethanol or water orally, twice daily for 6 days while the diet conditions were maintained. Abstinence symptoms were rated 6, 24, 48, and 72 hours after the last alcohol administration. Maintenance on a ketogenic diet caused a significant decrease in the alcohol withdrawal symptoms' "rigidity" and "irritability." Our preclinical pilot study suggests that a ketogenic diet may be a novel approach for treating alcohol withdrawal symptoms in humans. Copyright © 2017 by the Research Society on Alcoholism.

  10. Kindergarten Social Withdrawal and Reading Achievement: A Cross-Lagged Path Model for At-Risk Learners

    Science.gov (United States)

    Hall, Cristin M.; Welsh, Janet A.; Bierman, Karen L.; Nix, Robert

    2016-01-01

    The association between social withdrawal, school adjustment, and academic functioning in preschool and school entry is well-established. Children who experience social withdrawal in primary grades are at risk for decreased academic performance. The bidirectional relationships among early literacy and social withdrawal in primary grades have not…

  11. Use of a public film event to promote understanding and help seeking for social withdrawal.

    Science.gov (United States)

    Teo, Alan Robert; Stufflebam, Kyle Whitaker; Lu, Francis; Fetters, Michael Derwin

    2015-06-01

    This study aimed to implement a public film event about mental health aspects of social withdrawal. Secondary aims were to assess participants' knowledge, attitudes, and intended behaviors related to social withdrawal. The event, held at three U.S. sites, consisted of a film screening, question-and-answer session, and lecture. Participants completed a post-event survey. Of the 163 participants, 115 (70.6%) completed surveys. Most of the sample deemed social withdrawal a significant mental health issue. Regarding post-event intended behaviors, 90.2% reported intent to get more information, 48.0% to being vigilant for social withdrawal in others, and 19.6% to talking with a health care professional about concerns for social withdrawal in themselves or someone they knew. Asian participants were significantly more likely than non-Asians to intend to encourage help-seeking for social withdrawal (p = .001). A public film event may be a creative way to improve mental health awareness and treatment-seeking. © 2014 Wiley Publishing Asia Pty Ltd.

  12. Antihistamine Pretreatment to Reduce Incidence of Withdrawal Movement After Rocuronium Injection

    Science.gov (United States)

    Lee, Ho Jun; Han, Sung Jin; Kim, Heezoo; Lee, Il Ok; Kong, Myoung Hoon; Kim, Nan Suk; Lim, Sang Ho

    2009-01-01

    The purpose of this study was to determine the effectiveness of antihistamine therapy for withdrawal movements caused by rocuronium injection. One hundred seventy one ASA I-II adults undergoing elective surgery were randomly assigned to one of two groups. Patients in the control group (Group C) were premedicated with 2 mL normal saline, and those in the antihistamine group (Group A) were pre-medicated with 2 mL (45.5 mg) pheniramine maleate. After the administration of thiopental sodium 5 mg/kg, rocuronium 0.6 mg/kg was injected. Withdrawal movements were assessed using a four-grade scale. The administration of antihistamine reveals lower grade of withdrawal movement after rocuronium injection. PMID:19794987

  13. Brief report: Perceptions of social withdrawal during emerging adulthood in Lagos, Nigeria.

    Science.gov (United States)

    Bowker, Julie C; Ojo, Adesola Adebusola; Bowker, Matthew H

    2016-02-01

    The study of social withdrawal subtypes is no longer limited to Western societies but has extended to non-Western countries, such as China. This study considers, for the first time, social withdrawal subtypes in an African country (Nigeria) by examining emerging adults' (N = 151; 54% female; Mage = 19.92 years, SD = 2.54) perceptions, attitudes, and responses to shy, unsociable, and socially competent behaviors. Results revealed that Nigerian emerging adults perceived significant differences between shy, unsociable, and socially competent behavior in several ways incommensurate with participants of previous studies conducted in North America, Europe, and China. Findings highlight the diversity of social meanings attached to social withdrawal in non-Western societies, and point to the need for additional research on social withdrawal and its perception in Africa. Copyright © 2015 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.

  14. The pathogenesis of propranolol-withdrawal syndrome in essential hypertension.

    Science.gov (United States)

    Kristensen, B O; Steiness, E; Weeke, J

    1979-12-01

    1. In hypertension, the beta-adrenoreceptor-blocker-withdrawal syndrome comprises tachycardia, sweating, tremor and general malaise, symptoms resembling thyrotoxicosis. 2. The effect of abrupt cessation of propranolol on serum concentrations of thyroxine (T4) and triiodothyronine (T3) was therefore investigated in five patients with uncomplicated essential hypertension, treated with propranolol in doses from 160 to 480 mg/day. 3. Four of the five patients developed one or more of the above-mentioned symptoms within 2-6 days after withdrawal of propranolol. 4. A mean relative increase in serum free T3 of 51% (range 22-74%) was found in these four patients on the day of onset of symptoms. 5. The increase in free T3 in the five patients correlated positively with total serum propranolol on the last day the drug was given (r = 0.91, 2P = 0.03). 6. As an increase in T3 was found only in patients suffering the withdrawal syndrome, and was maximal the day the symptoms appeared, despite a variation in time of onset from 2 to 6 days, it is suggested that the beta-adrenoreceptor-blocker-withdrawal syndrome, at least partially, is caused by rebound increased production of T3, induced by the well-known inhibition of the monodeiodination of T4 to T3 during beta-adrenoreceptor blockade. 7. This assumption may explain the clinical symptoms and the reported transient increased beta-adrenoreceptor sensitivity with unchanged serum concentrations of catecholamines.

  15. Delirium and High Creatine Kinase and Myoglobin Levels Related to Synthetic Cannabinoid Withdrawal

    Directory of Open Access Journals (Sweden)

    Ahmet Bulent Yazici

    2017-01-01

    Full Text Available Synthetic cannabinoids (SCs are included in a group of drugs called new psychoactive substances. Effects of SCs on the central nervous system are similar to other cannabinoids, but 2–100 times more potent than marijuana. Thus, addiction and withdrawal symptoms are more severe than natural cannabinoids. Withdrawal symptoms of SCs were reported in the literature previously. But there is no report about SC withdrawal delirium and its treatment. Several studies reported that agonists of CB1 receptors play a role in GABA and glutamatergic neurotransmission, which is similar to the effects of alcohol on GABA and glutamatergic receptors. Previous studies on alcohol delirium cases suggested that elevated creatine kinase (CK can be a marker of progress. This study reports delirium and high serum CK levels related to SC withdrawal and offers a treatment with benzodiazepine for them. We described two cases treated in our inpatient clinic about SC withdrawal with increase of serum CK level and other laboratory parameters. One of them demonstrated delirium symptoms and the other did not with early rapid treatment.

  16. Amantadine as Augmentation in Managing Opioid Withdrawal with Clonidine: a randomized controlled trial.

    Directory of Open Access Journals (Sweden)

    Shahrokh Amiri

    2014-09-01

    Full Text Available Withdrawal symptoms are a main reason of continuous use of opioid. This study compares the efficacy of augmentation of amantadine with clonidine in decreasing opioid withdrawal symptoms.This double-blind randomized clinical trial was carried out in the detoxification and rehabilitation inpatient ward at Razi Hospital, Tabriz, Iran during 2012. The patients were randomly assigned to receive clonidine or clonidine plus amantadine; and withdrawal symptoms were evaluated in the admission day and 24, 48, and 72 hours later. Data were analyzed using SPSS by the 2*2 repeated analyses of variances (ANOVA.From the total of 69 participants, 30 patients completed the trial in each group. The severity of symptoms, however, had an increasing trend in both groups. Analysis of variance of the symptom severity score (by The Clinical Opiate Withdrawal Scale revealed a significant group-time interaction, and the patients who were receiving amantadine experienced milder symptoms.Treatment of opioid withdrawal symptoms with amantadine and clonidine would result in a better outcome compared with clonidine alone.

  17. Trajectories of abstinence-induced Internet gaming withdrawal symptoms: A prospective pilot study

    Directory of Open Access Journals (Sweden)

    Dean Kaptsis

    2016-12-01

    Full Text Available Internet Gaming Disorder (IGD is positioned in the appendix of the DSM-5 as a condition requiring further study. The IGD criteria refer to withdrawal symptoms, including irritability, anxiety, or sadness, that follow cessation of Internet gaming (APA, 2013. The aim of this study was to prospectively examine the nature of Internet gaming withdrawal symptoms, if they occur, under gaming abstinence conditions. This study employed a repeated-measures protocol to examine the cognitive-affective reactions of participants undertaking an 84-h Internet gaming abstinence period. The sample included individuals who met the IGD criteria as well as those who regularly played Internet games but did not meet the IGD criteria. Outcome variables included affect (positive and negative, psychological distress (depression, anxiety, stress, and Internet gaming withdrawal symptoms (craving/urge, thoughts about gaming, inability to resist gaming. A total of 24 participants (Mage = 24.6 years, SD = 5.8 were recruited from online gaming communities, and completed a series of online surveys before, during, and after abstaining from Massively Multiplayer Online (MMO games. Both the IGD group and the non-IGD group experienced an abstinence-induced decline in withdrawal symptomatology, negative affect, and psychological distress. The IGD group experienced its largest decline in withdrawal symptomatology within the first 24 h of abstinence. These preliminary data suggest that gaming withdrawal symptoms may follow, at least initially, negative linear and quadratic trends. Further prospective work in larger samples involving longer periods of abstinence is required to verify and expand upon these observations.

  18. Trajectories of abstinence-induced Internet gaming withdrawal symptoms: A prospective pilot study.

    Science.gov (United States)

    Kaptsis, Dean; King, Daniel L; Delfabbro, Paul H; Gradisar, Michael

    2016-12-01

    Internet Gaming Disorder (IGD) is positioned in the appendix of the DSM-5 as a condition requiring further study. The IGD criteria refer to withdrawal symptoms, including irritability, anxiety, or sadness, that follow cessation of Internet gaming (APA, 2013). The aim of this study was to prospectively examine the nature of Internet gaming withdrawal symptoms, if they occur, under gaming abstinence conditions. This study employed a repeated-measures protocol to examine the cognitive-affective reactions of participants undertaking an 84-h Internet gaming abstinence period. The sample included individuals who met the IGD criteria as well as those who regularly played Internet games but did not meet the IGD criteria. Outcome variables included affect (positive and negative), psychological distress (depression, anxiety, stress), and Internet gaming withdrawal symptoms (craving/urge, thoughts about gaming, inability to resist gaming). A total of 24 participants ( M age  = 24.6 years, SD  = 5.8) were recruited from online gaming communities, and completed a series of online surveys before, during, and after abstaining from Massively Multiplayer Online (MMO) games. Both the IGD group and the non-IGD group experienced an abstinence-induced decline in withdrawal symptomatology, negative affect, and psychological distress. The IGD group experienced its largest decline in withdrawal symptomatology within the first 24 h of abstinence. These preliminary data suggest that gaming withdrawal symptoms may follow, at least initially, negative linear and quadratic trends. Further prospective work in larger samples involving longer periods of abstinence is required to verify and expand upon these observations.

  19. 40 CFR 97.286 - Withdrawal from CAIR SO2 Trading Program.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Withdrawal from CAIR SO2 Trading... PROGRAMS (CONTINUED) FEDERAL NOX BUDGET TRADING PROGRAM AND CAIR NOX AND SO2 TRADING PROGRAMS CAIR SO2 Opt-in Units § 97.286 Withdrawal from CAIR SO2 Trading Program. Except as provided under paragraph (g) of...

  20. Rapid changes in plasma androgens during insulin withdrawal in male type 1 (insulin-dependent) diabetics

    DEFF Research Database (Denmark)

    Madsbad, S; Gluud, C; Bennett, Patrick

    1986-01-01

    Plasma concentrations of testosterone, androstenedione and dihydrotestosterone were measured in 15 Type 1 (insulin-dependent) diabetics with (n = 8) and without (n = 7) B-cell function during 12 h of insulin withdrawal and compared with those of 8 normal subjects. Before insulin withdrawal......, testosterone and dihydrotestosterone concentrations were lower in the diabetics after 4 h of insulin withdrawal and remained so throughout the study. The concentrations of androstenedione were not significantly different between diabetics and normal subjects except after 4 h of insulin withdrawal. Despite...