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Sample records for methysticum kava kava

  1. Herbicidal and Fungicidal Activities of Lactones in Kava (Piper methysticum).

    Science.gov (United States)

    Xuan, T D; Elzaawely, A A; Fukuta, M; Tawata, S

    2006-02-08

    This is the first report showing that kava lactones are plant and plant fungus growth inhibitors. Aqueous extract of kava roots showed high allelopathic potential and strongly suppressed germination and growth of lettuce, radish, barnyardgrass, and monochoria. Nine kava lactones were detected using GC-MS including desmethoxyyagonin, kavain, 7,8-dihydrokavain, hydroxykavain, yagonin, 5,6,7,8-tetrahydroxyyagonin, methysticin, dihydromethysticin, and 11-hydroxy-12-methoxydihydrokavain. Quantities of desmethoxyyagonin, kavain, 7,8-dihydrokavain, yagonin, methysticin, and dihydromethysticin detected were 4.3, 6.9, 18.6, 5.7, 1.4, and 5.4 mg/g of dry weight, respectively. These six major lactones in kava roots showed great herbicidal and antifungal activities. Growth of lettuce and barnyardgrass were significantly inhibited at 1-10 ppm, and four plant fungi including Colletotrichum gloeosporides, Fusarium solani, Fusarium oxysporum, and Trichoderma viride were significantly inhibited at 10-50 ppm. The biological activities of kava lactones were characterized by different double-bond linkage patterns in positions 5,6 and 7,8. The findings of this study suggest that kava lactones may be useful for the development of bioactive herbicides and fungicides.

  2. In vitro cytotoxicity of nonpolar constituents from different parts of kava plant (Piper methysticum).

    Science.gov (United States)

    Jhoo, Jin-Woo; Freeman, James P; Heinze, Thomas M; Moody, Joanna D; Schnackenberg, Laura K; Beger, Richard D; Dragull, Klaus; Tang, Chung-Shih; Ang, Catharina Y W

    2006-04-19

    Kava (Piper methysticum), a perennial shrub native to the South Pacific islands, has been used to relieve anxiety. Recently, several cases of severe hepatotoxicity have been reported from the consumption of dietary supplements containing kava. It is unclear whether the kava constituents, kavalactones, are responsible for the associated hepatotoxicity. To investigate the key components responsible for the liver toxicity, bioassay-guided fractionation was carried out in this study. Kava roots, leaves, and stem peelings were extracted with methanol, and the resulting residues were subjected to partition with a different polarity of solvents (hexane, ethyl acetate, n-butanol, and water) for evaluation of their cytotoxicity on HepG2 cells based on the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay and lactate dehydrogenase and aspartate aminotransferase enzyme leakage assays. Organic solvent fractions displayed a much stronger cytotoxicity than water fractions for all parts of kava. The hexane fraction of the root exhibited stronger cytotoxic effects than fractions of root extracted with other solvents or extracts from the other parts of kava. Further investigations using bioassay-directed isolation and analysis of the hexane fraction indicated that the compound responsible for the cytotoxicity was flavokavain B. The identity of the compound was confirmed by (1)H and (13) C NMR and MS techniques.

  3. Melanogenesis stimulation in murine B16 melanoma cells by Kava (Piper methysticum) rhizome extract and kavalactones.

    Science.gov (United States)

    Matsuda, Hideaki; Hirata, Noriko; Kawaguchi, Yoshiko; Naruto, Shunsuke; Takata, Takanobu; Oyama, Masayoshi; Iinuma, Munekazu; Kubo, Michinori

    2006-04-01

    Melanogenesis stimulation activity of aqueous ethanolic extracts obtained from several different parts of five Piper species, namely Piper longum, P. kadsura, P. methysticum, P. betle, and P. cubeba, were examined by using cultured murine B16 melanoma cells. Among them, the extract of P. methysticum rhizome (Kava) showed potent stimulatory effect on melanogenesis as well as P. nigrum leaf extract. Activity-guided fractionation of Kava extract led to the isolation of two active kavalactones, yangonin (2) and 7,8-epoxyyangonin (5), along with three inactive kavalactones, 5,6-dehydrokawain (1), (+)-kawain (3) and (+)-methysticin (4), and a glucosylsterol, daucosterin (6). 7,8-Epoxyyangonin (5) showed a significant stimulatory effect on melanogenesis in B16 melanoma cells. Yangonin (2) exhibited a weak melanogenesis stimulation activity.

  4. Measuring the chemical and cytotoxic variability of commercially available kava (Piper methysticum G. Forster.

    Directory of Open Access Journals (Sweden)

    Amanda C Martin

    Full Text Available Formerly used world-wide as a popular botanical medicine to reduce anxiety, reports of hepatotoxicity linked to consuming kava extracts in the late 1990s have resulted in global restrictions on kava use and have hindered kava-related research. Despite its presence on the United States Food and Drug Administration consumer advisory list for the past decade, export data from kava producing countries implies that US kava imports, which are not publicly reported, are both increasing and of a fairly high volume. We have measured the variability in extract chemical composition and cytotoxicity towards human lung adenocarcinoma A549 cancer cells of 25 commercially available kava products. Results reveal a high level of variation in chemical content and cytotoxicity of currently available kava products. As public interest and use of kava products continues to increase in the United States, efforts to characterize products and expedite research of this potentially useful botanical medicine are necessary.

  5. German Kava Ban Lifted by Court: The Alleged Hepatotoxicity of Kava (Piper methysticum) as a Case of Ill-Defined Herbal Drug Identity, Lacking Quality Control, and Misguided Regulatory Politics.

    Science.gov (United States)

    Kuchta, Kenny; Schmidt, Mathias; Nahrstedt, Adolf

    2015-12-01

    Kava, the rhizome and roots of Piper methysticum, are one of the most important social pillars of Melanesian societies. They have been used for more than 1000 years in social gatherings for the preparation of beverages with relaxing effects. During the colonial period, extract preparations found their way into Western medicinal systems, with experience especially concerning the treatment of situational anxiety dating back more than 100 years. It therefore came as a surprise when the safety of kava was suddenly questioned based on the observation of a series of case reports of liver toxicity in 1999 and 2000. These case reports ultimately led to a ban of kava products in Europe - a ban that has been contested because of the poor evidence of risks related to kava. Only recently, two German administrative courts decided that the decision of the regulatory authority to ban kava as a measure to ensure consumer safety was inappropriate and even associated with an increased risk due to the higher risk inherent to the therapeutic alternatives. This ruling can be considered as final for at least the German market, as no further appeal has been pursued by the regulatory authorities. However, in order to prevent further misunderstandings, especially in other markets, the current situation calls for a comprehensive presentation of the cardinal facts and misconceptions concerning kava and related drug quality issues. Georg Thieme Verlag KG Stuttgart · New York.

  6. The adverse effects of kava.

    Science.gov (United States)

    Kava, R

    2001-03-01

    In Fiji, kava is also known as yaqona or grog. A convenient sample of 300 kava drinkers in Nadi, Lautoka, Ba and Sigatoka were studied to see whether local people in Fiji experienced side effects of kava use. Because males usually consume kava in Fiji, we approached specific groups of people and asked them to participate in the survey. To evaluate the side effects of kava consumption, we interviewed housewives of male kava drinkers regarding specific effects of kava. We interviewed these housewives during kava drinking sessions since they were usually not taking part in the kava drinking. We also interviewed employers of these kava drinkers and the market vendors in Nadi Town since they were closely involved with kava drinkers. Wives of kava users felt deprived of basic family needs due to the amount of money spent on kava. In Urban schools, 64% males and 46.2% had tried kava. The present study aims to assess the prevalence of side effects of kava usage among a community sample of kava drinkers in Fiji and to compare the result with some of the side effects provided by other studies. The questionnaire also asked how much kava was consumed and the reasons. Since kava use is very much part of our everyday culture and existence, convincing people to change their behavior and kava consumption is a major tasks. I hope that this study would emphasize the need at a national level to educate people on the harmful effects of kava and the need for the health ministry to view very heavy kava intake as contributing to morbidity in Fiji.

  7. Toxicokinetics of Kava

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    Anthony Rowe

    2011-01-01

    Full Text Available Kava is traditionally consumed by South Pacific islanders as a drink and became popular in Western society as a supplement for anxiety and insomnia. Kava extracts are generally well tolerated, but reports of hepatotoxicity necessitated an international reappraisal of its safety. Hepatotoxicity can occur as an acute, severe form or a chronic, mild form. Inflammation appears to be involved in both forms and may result from activation of liver macrophages (Kupffer cells, either directly or via kava metabolites. Pharmacogenomics may influence the severity of this inflammatory response.

  8. Birgitta festivali kava teada

    Index Scriptorium Estoniae

    2008-01-01

    Augustis Tallinnas toimuva Birgitta festivali kavas ka humoristlik etendus "Kino ja komöödia" (viiuldaja Gidon Kremeri elust muusiku enda osavõtul), Don Juani teema käsitlus Hispaania flamenkoteatri esituses, G. Donizetti ooper "Maria Stuart" (Moskva Novaja Opera) ja B. Britteni ooper "Kruvipööre"

  9. Kava Linked to Liver Damage

    Science.gov (United States)

    ... of these countries to remove kava from the market. Although liver damage appears to be rare, the ... are marketed to men, women, children, and the elderly. Advice to Consumers Safety is a concern for ...

  10. Kava

    Science.gov (United States)

    ... with heart problems and eye irritation. Keep in Mind Tell all your health care providers about any ... Privacy and Policies Accessibility en Español FOIA Site Map Contact Us U.S. Department of Health & Human Services , ...

  11. The Health Effects of Kava/Sakau and Betel Nut.

    Science.gov (United States)

    Lee, Harvey

    For generations Pacific Islanders have used kava root and betel nut for a variety of cultural, medicinal, and ceremonial purposes: to overcome social barriers and lubricate social interactions; to cure bodily afflictions; and to accompany traditional and religious rituals. Kava, also known as ava, sakau, and yaqona has a long tradition as a…

  12. Stress-induced insomnia treated with kava and valerian: singly and in combination.

    Science.gov (United States)

    Wheatley, David

    2001-06-01

    Kava and valerian are herbal remedies that are claimed to have anxiolytic and sedative properties respectively, without dependence potential or any appreciable side effects. In this pilot study, 24 patients suffering from stress-induced insomnia were treated for 6 weeks with kava (LI-150), 120 mg daily. This was followed by a 2-week 'wash-out' period off treatment, and then, five patients having dropped out, 19 received valerian (LI-156), 600 mg daily, for another 6 weeks. Then there was a further 2-week period off treatment, and a final 6 weeks of treatment of these 19 patients with the two compounds combined (kava + valerian). Stress was measured in three areas: social, personal and life events; insomnia in three areas also: time to fall asleep, hours slept and waking mood. Total stress severity was significantly relieved by both compounds individually (p effects on kava, 10 (53%) on valerian and 10 (53%) on the combination. The 'commonest' effect was vivid dreams with kava + valerian (4 cases (21%)) and with valerian alone (3 cases (16%)), followed by gastric discomfort and dizziness with kava (3 cases each (3 %)). These results are considered to be extremely promising but further studies may be required to determine the relative roles of the two compounds for such indications. Copyright 2001 John Wiley & Sons, Ltd.

  13. Psychoactive substances of the South Seas: betel, kava and pituri.

    Science.gov (United States)

    Cawte, J

    1985-03-01

    Before white man brought his alcohol to the South Pacific, the indigenes were using many wild plants possessing psychoactive properties. The most prominent were betel in much of Melanesia, kava in much of Polynesia, and pituri in much of Australia. The use of each of these three drugs was widespread, institutionalised as a ritual and the occasion for extensive trade. Each was valued for its effect in reducing tension or in producing altered states of consciousness. Each was also capable of inducing intoxication. Since few physicians nowadays have had my opportunity to observe the use of all three of these substances, their main features are recalled here. Attention is paid to their traditional use and probable future use, to their pharmacological and clinical properties, and to their place in the zeitgeist of people and period. There is no indication that these substances will be espoused by the drug enthusiasts of the West as avidly as other ethno-psychopharmacological agents such as Peruvian coca leaf, the Indian hemp, the Asian poppy, or the American tobacco. The possibility, however, of some use in the West cannot be discounted.

  14. Kava and valerian in the treatment of stress-induced insomnia.

    Science.gov (United States)

    Wheatley, D

    2001-09-01

    Kava and valerian are herbal remedies, claimed to have anxiolytic and sedative properties respectively, without dependence potential or any appreciable side-effects. In this pilot study, 24 patients suffering from stress-induced insomnia were treated for 6 weeks with kava 120 mg daily. This was followed by 2 weeks off treatment and then, 5 having dropped out, 19 received valerian 600 mg daily for another 6 weeks. Stress was measured in three areas: social, personal and life-events; insomnia in three areas also: time to fall asleep, hours slept and waking mood. Total stress severity was significantly relieved by both compounds (p effects was 58% with each drug respectively and the 'commonest' effect was vivid dreams with valerian (16%), followed by dizziness with kava (12% ). These compounds may be useful in the treatment of stress and insomnia but further studies are required to determine their relative roles for such indications. Copyright 2001 John Wiley & Sons, Ltd.

  15. Driving following Kava Use and Road Traffic Injuries: A Population-Based Case-Control Study in Fiji (TRIP 14).

    Science.gov (United States)

    Wainiqolo, Iris; Kafoa, Berlin; Kool, Bridget; Robinson, Elizabeth; Herman, Josephine; McCaig, Eddie; Ameratunga, Shanthi

    2016-01-01

    To investigate the association between kava use and the risk of four-wheeled motor vehicle crashes in Fiji. Kava is a traditional beverage commonly consumed in many Pacific Island Countries. Herbal anxiolytics containing smaller doses of kava are more widely available. Data for this population-based case-control study were collected from drivers of 'case' vehicles involved in serious injury-involved crashes (where at least one road user was killed or admitted to hospital for 12 hours or more) and 'control' vehicles representative of 'driving time' in the study base. Structured interviewer administered questionnaires collected self-reported participant data on demographic characteristics and a range of risk factors including kava use and potential confounders. Unconditional logistic regression models estimated odds ratios relating to the association between kava use and injury-involved crash risk. Overall, 23% and 4% of drivers of case and control vehicles, respectively, reported consuming kava in the 12 hours prior to the crash or road survey. After controlling for assessed confounders, driving following kava use was associated with a four-fold increase in the odds of crash involvement (Odds ratio: 4.70; 95% CI: 1.90-11.63). The related population attributable risk was 18.37% (95% CI: 13.77-22.72). Acknowledging limited statistical power, we did not find a significant interaction in this association with concurrent alcohol use. In this study conducted in a setting where recreational kava consumption is common, driving following the use of kava was associated with a significant excess of serious-injury involved road crashes. The precautionary principle would suggest road safety strategies should explicitly recommend avoiding driving following kava use, particularly in communities where recreational use is common.

  16. Driving following Kava Use and Road Traffic Injuries: A Population-Based Case-Control Study in Fiji (TRIP 14.

    Directory of Open Access Journals (Sweden)

    Iris Wainiqolo

    Full Text Available To investigate the association between kava use and the risk of four-wheeled motor vehicle crashes in Fiji. Kava is a traditional beverage commonly consumed in many Pacific Island Countries. Herbal anxiolytics containing smaller doses of kava are more widely available.Data for this population-based case-control study were collected from drivers of 'case' vehicles involved in serious injury-involved crashes (where at least one road user was killed or admitted to hospital for 12 hours or more and 'control' vehicles representative of 'driving time' in the study base. Structured interviewer administered questionnaires collected self-reported participant data on demographic characteristics and a range of risk factors including kava use and potential confounders. Unconditional logistic regression models estimated odds ratios relating to the association between kava use and injury-involved crash risk.Overall, 23% and 4% of drivers of case and control vehicles, respectively, reported consuming kava in the 12 hours prior to the crash or road survey. After controlling for assessed confounders, driving following kava use was associated with a four-fold increase in the odds of crash involvement (Odds ratio: 4.70; 95% CI: 1.90-11.63. The related population attributable risk was 18.37% (95% CI: 13.77-22.72. Acknowledging limited statistical power, we did not find a significant interaction in this association with concurrent alcohol use.In this study conducted in a setting where recreational kava consumption is common, driving following the use of kava was associated with a significant excess of serious-injury involved road crashes. The precautionary principle would suggest road safety strategies should explicitly recommend avoiding driving following kava use, particularly in communities where recreational use is common.

  17. The social, cultural and medicinal use of kava for twelve Tongan born men living in Auckland, New Zealand.

    Science.gov (United States)

    Nosa, Vili; Ofanoa, Malakai

    2009-02-01

    Kava consumption is a very popular practise amongst Pacific people especially amongst the Tongan communities. The purpose of this paper is to identify some of the key cultural, social and medicinal elements of kava use amongst Tongan men. Twelve face to face interviews in this study were undertaken. The paper argues that kava drinking is strongly linked to many of the ceremonial, social and cultural obligations that are deeply embedded within the Tongan culture. The positive uses of kava include medicinal purposes, male bonding, alternative to alcohol consumption, reaffirming and establishing relationships amongst other Tongan men, The men also stated negative uses of kava such as it made them lazy, tired so they were not able to go to work, a lack of sexual activities by being too tired have sex with their partners, and very expensive to buy in New Zealand. The aim of this paper is to discuss and examine the social, cultural and medicinal kava use amongst twelve Tongan born men living in Auckland, New Zealand. The study used qualitative methods, specifically individual interviews were conducted in Tongan or English. Participants were recruited through community networks in Auckland. A number of Tongan churches, Tongan medical clinics such as Langimailie, and kava clubs were approached to recruit participants. The open ended interview schedule covered themes such as access, quantity, frequency, and problems associated with kava use. The interviews were conducted by a Tongan researcher either in English or Tongan. All interviews were translated and transcribed into English. A thematic analysis based on multiple readings of the transcripts was used The analysis identified commonalities and differences. The study was granted ethical approval by the University of Auckland Human Subjects Ethics Committee in December 2004. Interviews were conducted at the beginning of 2005. Interviews were undertaken in a place where the participants felt comfortable. Interview times

  18. Long-term monitoring of Sgr A* at 7 mm with VERA and KaVA

    Science.gov (United States)

    Akiyama, K.; Kino, M.; Sohn, B.; Lee, S.; Trippe, S.; Honma, M.

    2014-05-01

    We present the results of radio monitoring observations of Sgr A* at 7 mm (i.e. 43 GHz) with the VLBI Exploration of Radio Astrometry (VERA), which is a VLBI array in Japan. VERA provides angular resolution on millisecond scales, resolving structures within 100 Schwarzschild radii of Sgr A* , similar to the Very Large Baseline Array (VLBA). We performed multi-epoch observations of Sgr A* in 2005 - 2008, and started monitoring it again with VERA from 2013 January to trace the current G2 encounter event. Our preliminary results in 2013 show that Sgr A* on mas scales has been in an ordinary state as of August 2013, although some fraction of the G2 cloud already passed the pericenter of Sgr A* in April 2013. We will continue monitoring Sgr A* with VERA and the newly developed KaVA (KVN and VERA Array).

  19. The risk-benefit profile of commonly used herbal therapies: Ginkgo, St. John's Wort, Ginseng, Echinacea, Saw Palmetto, and Kava.

    Science.gov (United States)

    Ernst, Edzard

    2002-01-01

    Because use of herbal remedies is increasing, a risk-benefit profile of commonly used herbs is needed. This article provides a clinically oriented overview of the efficacy and safety of ginkgo, St. John's wort, ginseng, echinacea, saw palmetto, and kava. Wherever possible, assessments are based on systematic reviews of randomized clinical trials. Encouraging data support the efficacy of some of these popular herbal medicinal products, and the potential for doing good seems greater than that for doing harm. The published evidence suggests that ginkgo is of questionable use for memory loss and tinnitus but has some effect on dementia and intermittent claudication. St. John's wort is efficacious for mild to moderate depression, but serious concerns exist about its interactions with several conventional drugs. Well-conducted clinical trials do not support the efficacy of ginseng to treat any condition. Echinacea may be helpful in the treatment or prevention of upper respiratory tract infections, but trial data are not fully convincing. Saw palmetto has been shown in short-term trials to be efficacious in reducing the symptoms of benign prostatic hyperplasia. Kava is an efficacious short-term treatment for anxiety. None of these herbal medicines is free of adverse effects. Because the evidence is incomplete, risk-benefit assessments are not completely reliable, and much knowledge is still lacking.

  20. Coltsfoot as a potential cause of deep vein thrombosis and pulmonary embolism in a patient also consuming kava and blue vervain.

    Science.gov (United States)

    Freshour, Jessica E; Odle, Brian; Rikhye, Somi; Stewart, David W

    2012-09-01

    To report a case of deep vein thrombosis (DVT) with symptomatic pulmonary embolism (PE) possibly associated with the use of coltsfoot, kava, or blue vervain. A 27-year-old white male presented with leg pain and swelling, tachycardia, and pleuritic chest pain. He had no significant medical history. A medication history revealed extensive herbal medication use including: coltsfoot, passionflower, red poppy flower petals, wild lettuce, blue lily flowers, wild dagga flowers, Diviners Three Burning Blend® (comprised of salvia divinorum, blue lily, and wild dagga), kava-kava, St. John's Wort, blue vervain, and Dreamer's Blend® (comprised of Calea zacatechichi, vervain, Entada rheedii, wild lettuce, and Eschscholzia californica). Lower extremity Doppler ultrasound and computed topography (CT) of the chest revealed DVT and PE. A hypercoagulable work-up was negative. The patient was treated with enoxaparin and warfarin and was discharged home. While no distinct agent can be identified as a sole cause of this venous thromboembolic event, coltsfoot could potentially affect coagulation through its effect on vascular endothelial cells as they regulate nitric oxide. Nitric oxide is a known mediator of platelet activity and coagulation, particularly in the pulmonary vasculature. Kava and vervain have estrogenic properties. Of the medications consumed by this self-proclaimed "herbalist," coltsfoot is a potential cause of venous thromboembolic disease (VTE).

  1. Interações medicamentosas de fitoterápicos e fármacos: Hypericum perforatum e Piper methysticum

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    C. H.G. Cordeiro

    Full Text Available A utilização de produtos naturais na medicina popular é milenar e persiste até os dias atuais. Entretanto, a idéia de que estes produtos são isentos de toxicidade torna o uso de medicamentos fitoterápicos cada vez maior e indiscriminado. Este trabalho trata de uma revisão sobre as interações que podem ocorrer com a utilização concomitante de Hypericum perforatum L. (erva de são joão e Piper methysticum F. (kava-kava com fármacos, podendo levar a sérios efeitos tóxicos, incluindo a fatalidade.

  2. SiO MASERS AROUND WX PSC MAPPED WITH THE KVN AND VERA ARRAY (KaVA)

    Energy Technology Data Exchange (ETDEWEB)

    Yun, Youngjoo; Cho, Se-Hyung; Kim, Jaeheon; Choi, Yoon Kyung; Kim, Dong-Jin; Yoon, Dong-Hwan; Byun, Do-Young; Chung, Hyunsoo; Chung, Moon-Hee; Han, Myoung-Hee [Korea Astronomy and Space Science Institute, 776 Daedeok-daero, Yuseong, Daejeon 305-348 (Korea, Republic of); Imai, Hiroshi; Oyadomari, Miyako [Graduate School of Science and Engineering, Kagoshima University, 1-21-35 Korimoto, Kagoshima 890-0065 (Japan); Asaki, Yoshiharu [National Astronomical Observatory of Japan (NAOJ) Chile Observatory/Joint ALMA Observatory (JAO), Alonso de Cordova 3107, Vitacura 763 0355, Santiago (Chile); Chibueze, James O. [Department of Physics and Astronomy, Faculty of Physical Sciences, University of Nigeria, Carver Building, 1 University Road, Nsukka (Nigeria); Dodson, Richard; Rioja, María J. [International Centre for Radio Astronomy Research, M468, The University of Western Australia, 35 Stirling Hwy, Crawley, Western Australia 6009 (Australia); Kusuno, Kozue [Department of Space and Astronautical Science, School of Physical Sciences, The Graduate University for Advanced Studies (SOKENDAI), 3-1-1 Yoshinodai, Chuou-Ku, Sagamihara, Kanagawa 252-5210 (Japan); Matsumoto, Naoko; Hagiwara, Yoshiaki [Mizusawa VLBI Observatory, National Astronomical Observatory of Japan, 2-21-1 Osawa, Mitaka, Tokyo 181-8588 (Japan); Min, Cheulhong, E-mail: yjyun@kasi.re.kr, E-mail: cho@kasi.re.kr [Department of Astronomical Sciences, The Graduate University for Advanced Studies (SOKENDAI), 2-21-1 Osawa, Mitaka, Tokyo 181-8588 (Japan); and others

    2016-05-01

    We present the first images of the v = 1 and v = 2 J = 1 → 0 SiO maser lines taken with KaVA, i.e., the combined array of the Korean Very Long Baseline Interferometry (VLBI) Network and the VLBI Exploration of Radio Astrometry (VERA), toward the OH/IR star WX Psc. The combination of long and short antenna baselines enabled us to detect a large number of maser spots, which exhibit a typical ring-like structure in both the v = 1 and v = 2 J = 1 → 0 SiO masers as those that have been found in previous VLBI observational results of WX Psc. The relative alignment of the v = 1 and v = 2 SiO maser spots are precisely derived from astrometric analysis, due to the absolute coordinates of the reference maser spot that were well determined in an independent astrometric observation with VERA. The superposition of the v = 1 and v = 2 maser spot maps shows a good spatial correlation between the v = 1 and v = 2 SiO maser features. Nevertheless, it is also shown that the v = 2 SiO maser spot is distributed in an inner region compared to the v = 1 SiO maser by about 0.5 mas on average. These results provide good support for the recent theoretical studies of the SiO maser pumping, in which both the collisional and the radiative pumping predict the strong spatial correlation and the small spatial discrepancy between the v = 1 and v = 2 SiO maser.

  3. Dietary feeding of flavokawain A, a Kava chalcone, exhibits a satisfactory safety profile and its association with enhancement of phase II enzymes in mice

    Directory of Open Access Journals (Sweden)

    Xuesen Li

    2014-01-01

    Full Text Available Flavokawain A (FKA, a major chalcone in the Kava plant, has recently demonstrated promising anti-cancer activities. A systematic evaluation of FKA's safety profile has not been reported before. In this study, male FVB/N mice were fed with an AIN-76A diet or AIN-76A diet supplemented with 0.6% (6 g/kg food FKA or 0.6% commercial kava root extract (KRE for three weeks. Dietary feeding of FKA did not affect food consumption and body weight. Histopathological examination of liver, kidney, colon, lung, heart, spleen, and thymus revealed no signs of FKA-induced toxicity. Biochemical serum analysis and histological examination confirmed normal organ function in FKA-treated mice. The cytotoxicity profile showed FKA had minimal side effects on bone marrow and small intestinal epithelial cells compared with Adriamycin. In addition, oral feeding of FKA increased activities of both glutathione S-transferase and quinone reductase in the liver, lung, prostate and bladder tissues of mice. In comparison, dietary feeding of 0.6% KRE increased liver/body weight ratio and decreased spleen, thymus, and testis/body weight ratios, as well as induced nodular proliferation in liver tissues. Therefore, dietary feeding FKA showed no adverse effects on major organ function and homeostasis in mice, suggesting the potential of FKA for chemoprevention study of human cancers.

  4. President kritiseeris koolide kinnisvara arendamise kava

    Index Scriptorium Estoniae

    2004-01-01

    Ilmunud ka ajalehes Koit (2004/Sep/18) lk. 2. President Arnold Rüütli ja haridus- ja teadusminister Toivo Maimetsa ettekannetest üleriigilisel konverentsil "21. sajandi haridus". Üldhariduskoolide kinnisvara arendamise programmi tutvustas Riigi Kinnisvara ASi projektidirektor Tiit Kerem

  5. Kontserdihooaeg toob kireva kava / Silja Joon

    Index Scriptorium Estoniae

    Joon, Silja, 1966-

    2007-01-01

    Pärnu kontserdimaja algavast kontserdihooajast: 22. sept.avakontsert "Pärt Pärnus", 13. okt.Four Freshmen, märtsis A'Cappella ExpreSSS, 3. apr. Voiceboys, veebr. Radu Marian ja Trio Barocco, 30. dets. Hennessy aastalõpukontsert, 12. apr. "Rock ja raga"

  6. Keskkonnakasutuse kava kui halduse tegevusvorm / Ivo Pilving

    Index Scriptorium Estoniae

    Pilving, Ivo, 1975-

    2010-01-01

    Keskkonnaõiguslike kavade (õhusaaste tegevuskava, müra vähendamise tegevuskava, veemajanduskava, jäätmekava, hoiu- või kaitseala kaitsekorralduskava ja liigi kaitse ja ohjamise tegevuskava) kasutamise võimalustest Eesti õiguskorras

  7. Siim Kallas tutvustas nelja riigi presidentidele Rail Balticu kava

    Index Scriptorium Estoniae

    2011-01-01

    Euroopa Komisjoni transpordivolinik Siim Kallas tutvustas 2. detsembril 2011 Vihula mõisas president Toomas Hendrik Ilvesele, Läti presidendile Andris Bērziņšile, Leedu presidendile Dalia Grybauskaitėle ja Poola presidendile Bronisław Komorowskile Baltimaid ülejäänud Euroopaga ühendava Rail Balticu projekti

  8. 3 ilusat naist PÖFFi kavas / Kaarel Kuurmaa

    Index Scriptorium Estoniae

    Kuurmaa, Kaarel

    2010-01-01

    14. Pimedate Ööde filmifestival: Euroopa Filmiakadeemia parima naisnäitleja auhinnale kandideerivad Zrinka Cvitešic "Teel" (Bosnia-Herzegovina jt. 2010), Sibel Kekilli "Võõras" (Saksamaa 2010) ja Lotte Verbeek"Ei midagi isiklikku" (Iiri-Holland 2009)

  9. Eesti vajab kiiresti euroabi vastuvõtmise kava / Rupinder Singh

    Index Scriptorium Estoniae

    Singh, Rupinder

    2003-01-01

    Autor leiab, et EL-i liikmelisus annab võimaluse püsivaks ja õiglaseks majanduskasvu koefitsiendiks, kuid vaid juhul, kui potentsiaalsed võimalused ära kasutatakse. Ta rõhutab tugeva poliitilise juhtimise ja strateegilise planeerimise vajalikkust valmistamaks ette infrastruktuuri EL-i rahade kasutamiseks. Samas pole Baltimaades tema hinnangul hetkel isegi piisavalt inimesi EL-i finantsvoogude suure potentsiaaliga tegelemiseks.

  10. Renault näitas maailma vallutamise kava / Margus Mihkels

    Index Scriptorium Estoniae

    Mihkels, Margus

    2006-01-01

    Ilmunud ka: Postimees : na russkom jazõke 13. veebr. lk. 10. Prantsuse autotootja Renault juhatuse esimees Carlos Ghosn tutvustas 9. veebruaril Pariisi kogunenud ajakirjanikele firma kolme lähima aasta tegevusplaani, mille eesmärgiks on saada aastaks 2009 Euroopa kõige kasumlikumaks autotootjaks. Autotootja kolmest tähtsamast vahe-eesmärgist

  11. Cannes'i filmifestivali kava tuleb kirju / Andres Laasik

    Index Scriptorium Estoniae

    Laasik, Andres, 1960-2016

    2004-01-01

    Cannes'i festival toimub 12.-23. maini, žüriid juhib Quentin Tarantino, sinna kuulub ka Peter von Bagh. Avafilmiks saab Pedro Almodovari "Vilets haridus" ("La mala educacion") ja lõpetajaks Irwin Winkleri Cole Porterit portreteeriv "De-Lovely"

  12. Vallo Reimaa : Kavas ei ole mingit omavalitsuse reformi / Vallo Reimaa

    Index Scriptorium Estoniae

    Reimaa, Vallo

    2007-01-01

    Regionaalminister Vallo Reimaa vastab online-intervjuus küsimustele, mitu maakonda on Eestis nelja aasta pärast, mida ta arvab ideest kaotada regionaalministri koht, kas on reaalne vähendada nii omavalitsusi kui ka ametnike arvu

  13. U.S. Navy Aeromedical Reference and Waiver Guide

    Science.gov (United States)

    2010-05-05

    Passion flower) – Piper methysticum (Kava-Kava) – Psilocybe semilanceata (magic mushrooms) – Rauwolfia serpentina (Indian snakeroot) – Rauwolfia... serpentina (Indian Snakeroot) – Scilla maritima (White Squill) – Scopolia carniolica (Scopolia)* U.S. Navy Aeromedical Reference and Waiver Guide...be sedatives: – Valeriana officinalis (Valerian) – Rauwolfia serpentina (Indian snakeroot) – Atropa belladonna (Deadly Nightshade)* – Chelidonium

  14. Tuleva aasta riigielarve kavas laiutab 300 miljoni kroonine auk / Kai Kalamees

    Index Scriptorium Estoniae

    Kalamees, Kai

    1998-01-01

    Riigikogu ei kinnitanud autode aktsiisi tõstmise seaduseelnõud, mistõttu järgmise aasta riigieelarvesse tekkis 300 miljoni kroonine puudujääk. Ilmunud ka: Kupetsheskaja Gavan : Gazeta Vzgljad, 5. nov. 1998, lk. 10

  15. Anneli Remme soovitab : Kammerdžässi kava "Jõulud mõisas" / Siim Nestor

    Index Scriptorium Estoniae

    Nestor, Siim, 1974-

    2006-01-01

    Eesti-Tšiili trio Raivo Tafenau - Meelis Vind - Ricardo Padilla kontsertidest sarja "Mõisaromantika" raames 25. nov. Taagepera lossis Valgamaal, 26. nov. Tõstamaa mõisas Pärnumaal ja 16. dets. Vihterpalu mõisas Harjumaal

  16. Täna algava Annecy festivali kavas on kolm Eesti joonisfilmi

    Index Scriptorium Estoniae

    2007-01-01

    Annecy animafestivalil osaleb kolm Eesti filmi : võistleb Kaspar Jancise "Maraton", Panorama programmis on Ülo Pikkovi "Elu maitse", võistlusvälises täispikkade filmide programmis on Janno Põldma-Heiki Ernitsa "Leiutajateküla Lotte"

  17. Uus kava lükkab Kosovo iseseisvumise edasi / Jürgen Tamme

    Index Scriptorium Estoniae

    Tamme, Jürgen

    2007-01-01

    Uus ÜRO resolutsioonikava ei maini erivolinik Martti Ahtisaari välja pakutud ideed Kosovo piiratud iseseisvusest ja näeb ette vaid kõneluste taaselustamise Serbia ja sõltumatust taotleva Kosovo vahel. Vt. samas: Serbia ja Kosovo vägikaikavedu

  18. Kogu Eestimaa internetiseerimise kava jääb sel aastal veel lõpetamata / Margus Konnula

    Index Scriptorium Estoniae

    Konnula, Margus, 1974-

    2007-01-01

    Interneti leviala ei ole veel jõudnud Vormsi saarele ega Mahtra külla, projekti Külatee 3 raames otsitakse nn. leviaukudele veel lahendusi. Internetiportaali www.WiFi.ee toimetaja Veljo Haameri väitel on Eestis tuhandeid probleemseid kohti ning Eesti ei ole kindlasti maailma juhtriik inimeste "digitaalses kaasamises". Kaart: Kõue interneti leviala

  19. Konserthuset Göteborg - 21. oktober 1995 kl. 15.00 Stora Salen. I avslutning till Estival 95 Estniska Kulturdagar i Göteborg : [kontserdi kava

    Index Scriptorium Estoniae

    1995-01-01

    Erkki-Sven Tüür: Insula deserta für strakorkester W. A. Mozart: vesperae solennes de confessore K 339; Eduard Tubin: Piano concertino; L. v. Beethoven: Fantasi c-moll för piano, kör och orkester, op. 80. Göteborger Symphoniker, dirigent Neeme Järvi. Solister: Vardo Rumessen, piano; Kaia Urb, sopran; Riina Airenne, mezzosopran; Mati Kõrts, tenor; Uku Joller, bas. Estniska Gosskören, Venno Laul. Esinejate lühitutvustus

  20. Kontserdijärgseid mõtteid / Niina Murdvee

    Index Scriptorium Estoniae

    Murdvee, Niina, 1950-

    1999-01-01

    Ü. Kaadu esinemisest 29. aprillil Estonia kontserdisaalis. Kavas Tshaikovski Viiulikontsert. M. Mikalai ja O. Voronova ühiskontserdist 30.aprillil Tallinna raekojas. Kavas Bach, Debussy, Liszt, Eller ja Ravel

  1. Sleep Disorders and Complementary Health Approaches

    Science.gov (United States)

    ... Resources CME/CEU and Online Lectures Online Continuing Education Series Distinguished Lecture Series Integrated Medicine Research Lecture ... R, Sarris J, Schweitzer I. Kava hepatotoxicity in traditional and modern use: the presumed Pacific kava paradox hypothesis revisited. ...

  2. Kontserdipeegel / Igor Garshnek

    Index Scriptorium Estoniae

    Garšnek, Igor, 1958-

    1999-01-01

    Organisti kontserdist 10. nov. Niguliste kirikus. Kavas J.P.E. Hartmanni, D. Buxtehude ja C. Nielseni orelimuusika. 12. nov. Estonia kontserdisaalis toimunud kontserdist. Kavas W. A. Mozarti "Reekviem"

  3. Filmi- ja videofestival kolis Port Arturisse / Silja Joon

    Index Scriptorium Estoniae

    Joon, Silja, 1966-

    2009-01-01

    Pärnu filmi- ja videofestival 2009 Port Artur 2 kaubanduskeskuses. Näeb videoinstallatsioonide kava ja noorteprogrammi. Korraldab Non Grata. Videoprogrammi koostab Al Paldrok, virtuaalmeedia osa Raivo Kelomees, filmiprogrammi Andres Maimik ja installatsioonide erikava Taje Tross. Festivali kava

  4. Magustoiduks rahvusvahelise kuulsusega meistrid / Helju Keskpalu

    Index Scriptorium Estoniae

    Keskpalu, Helju

    1999-01-01

    R. Boucheri kontserdist Valgas. Kavas J. Polaki, G. F. Händeli, E. Granadose, J. Marchandi ja J. Rodrigo kitarrimuusika. M. Rubackite kontserdist Valga muusikakoolis. Kavas J. S. Bachi, L. van Beethoveni ja R. Schumanni klaverilooming

  5. Kontserdipeegel / Igor Garshnek

    Index Scriptorium Estoniae

    Garšnek, Igor, 1958-

    1999-01-01

    27. sept. toimunud kontserdist Estonia kontserdisaalis. Kavas B.Eno "Music for Airports". Rahvusvahelise muusikapäeva kontserdist 1. okt. Kavas M.Stachowski "Choreias, W.Lutoslawski Sümf. nr. 4 ja J.MacMillani löökriistakontsert "Veni, veni, Emmanuel". 3. okt. Rotermanni soolalaos toimunud kontserdist. Kavas Nielseni, T.Takemitsu ja R.Straussi muusika

  6. Kuidas suunata noori loodusest hoolima? / Jane Adler

    Index Scriptorium Estoniae

    Adler, Jane

    2008-01-01

    Kuusalu keskkoolis toimunud ökotantsufestivalist. Kolm peapreemiat anti välja parimatele looduse jäljendajatele: Keila lasteaiale "Vikerkaar" kava "Linnud ja meri" eest, Petsi spordiklubile (1.-3. klass) kava "Kärbeste ralli" eest ning Kunda ühisgümnaasiumile (10.-12. klass) kava "Elu" eest

  7. In vivo antitumor and antimetastatic effects of flavokawain B in 4T1 breast cancer cell-challenged mice

    Directory of Open Access Journals (Sweden)

    Abu N

    2015-03-01

    Full Text Available Nadiah Abu,1,2 Nurul Elyani Mohamed,2 Swee Keong Yeap,3 Kian Lam Lim,4 M Nadeem Akhtar,5 Aimi Jamil Zulfadli,3 Beh Boon Kee,2 Mohd Puad Abdullah,2 Abdul Rahman Omar,3 Noorjahan Banu Alitheen2 1Bright Sparks Unit, Universiti Malaya, Kuala Lumpur, Malaysia; 2Department of Cell and Molecular Biology, Faculty of Biotechnology and Biomolecular Sciences, 3Institute of Bioscience, Universiti Putra Malaysia, Serdang, Selangor Darul Ehsan, Malaysia; 4Faculty of Medicine and Health Sciences, Universiti Tunku Abdul Rahman, Lot PT, Jalan Sungai Long, Bandar Sungai Long, Cheras, Selangor, Malaysia; 5Faculty of Industrial Sciences and Technology, Universiti Malaysia Pahang, Lebuhraya Tun Razak, Kuantan Pahang, Malaysia Abstract: Flavokawain B (FKB is a naturally occurring chalcone that can be isolated through the root extracts of the kava-kava plant (Piper methysticum. It can also be synthesized chemically to increase the yield. This compound is a promising candidate as a biological agent, as it is reported to be involved in a wide range of biological activities. Furthermore, FKB was reported to have antitumorigenic effects in several cancer cell lines in vitro. However, the in vivo antitumor effects of FKB have not been reported on yet. Breast cancer is one of the major causes of cancer-related deaths in the world today. Any potential treatment should not only impede the growth of the tumor, but also modulate the immune system efficiently and inhibit the formation of secondary tumors. As presented in our study, FKB induced apoptosis in 4T1 tumors in vivo, as evidenced by the terminal deoxynucleotidyl transferase dUTP nick end labeling and hematoxylin and eosin staining of the tumor. FKB also regulated the immune system by increasing both helper and cytolytic T-cell and natural killer cell populations. In addition, FKB also enhanced the levels of interleukin 2 and interferon gamma but suppressed interleukin 1B. Apart from that, FKB was also found to inhibit

  8. PÖFF-i alafestivalid lükati käima

    Index Scriptorium Estoniae

    2010-01-01

    14. korda toimuva Pimedate Ööde Filmifestivali tänavune fookus on soome filmidel ja Euroopa filmiauhindade nominentide töödel. PÖFF-i põhiprogrammi tutvustab peakorraldaja Tiina Lokk, tudengi- ja lühifilmide festivali Sleepwalkers kava festivali juht Helen Vinogradov, animafilmide festivali Animated Dreams kava programmijuht Heilika Pikkov, laste- ja noortefilmide festivali Just Film kava festivali juht Mikk Granström

  9. Haapsalu Lossiaed erastamise keerises / Toivo Meikar

    Index Scriptorium Estoniae

    Meikar, Toivo, 1947-

    2002-01-01

    Haapsalu lossiaia juriidilisest kuuluvusest, 1920. a. esimese poole vaidluste ja kohtuprotsesside tagapõhjast ning tulemist. Lisa: Haapsalu linna plaanid, lossiaia kruntimise kava, lossiaia üldplaan

  10. Loomulik ja loominguline koostööprojekt "Ruhrpott" : Ruhri katel / Heli Meisterson ; interv. R[eet] V[arblane

    Index Scriptorium Estoniae

    Meisterson, Heli

    2007-01-01

    Goethe Instituudi kultuuriprogrammide referent Heli Meisterson Nordrhein-Westfaleni Liidumaa kultuurifestifalist "Ruhrpott" Eestis, programmist. 2006. a. eelnenud Baltimaade kultuurifestivali "scene nrw" kava koostamisest

  11. Piip ja Tuut ootavad Amarillosse ja Coca-Cola Plazasse perepäevale

    Index Scriptorium Estoniae

    2004-01-01

    Kord kuus, septembrist 2004 kuni 2005.a. maini korraldatavatest perepäevadest. C-C Plazas on perepäevade ajal kavas eriprogramm ja enne või pärast filmi on pered oodatud Viru hotelli restorani Amarillo, kus kavas spetsiaalne lasteprogramm klounidelt Piip ja Tuut

  12. Kontserdipeegel : ERSO, Nordic Voices ja NYYD Ensemble / Igor Garshnek

    Index Scriptorium Estoniae

    Garšnek, Igor, 1958-

    1999-01-01

    22. sept. Estonia kontserdisaalis toimunud ERSO kontserdist. Kavas Debussy "Fauni pärastlõuna", R.Straussi Oboekontsert ja F.Mendelssohni 4. sümfoonia. 24. sept. Estonia kontserdisaalis toimunud ans. Nordic Voices kontserdist. ETV suures stuudios toimunud multimeediaetendusest. Kavas M.Nymani "Letters, Riddles & Writs" ja L.Andriesseni "M is for Man, Music, Mozart"

  13. Uudised : Kuldmedal Sergei Upkinile. Balletipreemiad. Hartshenko tantsib Pariisi / Heili Vaus-Tamm

    Index Scriptorium Estoniae

    Vaus-Tamm, Heili, 1961-

    2000-01-01

    19.-25. apr. Permis toimunud rahvusvahelisest balletiartistide konkursist "Arabesk 2000". 29. apr. antakse Estonia talveaias üle tänavused Philip Morrise balletiauhinnad. 4. mail esitatakse Tallinna Raekojas viimane kava sarjast "Ajastu muusikas ja tantsus". Kava pealkiri "Pariis 1930"

  14. Maakonda esindavad lõbusad klounid / Anne Põder

    Index Scriptorium Estoniae

    Põder, Anne, 1973-

    2007-01-01

    Tantsufestivali "Koolitans 2007" lõppkontserdile valisid hindajad Järvamaad esindama spordiklubi Maribel rühma Alice, kes esitab kava "Lõbusad klounid". Rühma treener ja kava kokkupanija on Kerli Graubner. Lisatud žüriiliikme Kristin Pukka kommentaar

  15. Kontserdipeegel / Igor Garshnek

    Index Scriptorium Estoniae

    Garšnek, Igor, 1958-

    2001-01-01

    21.XI Estonia kontserdisaalis esines Eesti-Soome Sümfooniaorkester, kavas Viini klassikud. 23.XI toimus kontsert "Joaquín Rodrigo 100", kus ERSOt juhatas Toomas Vavilov. 30.XI esines Estonia kontserdisaalis ERSO Nikolai Aleksejevi dirigeerimisel, kavas Brahmsi, Stravinski teosed ja Toivo Tulevi Viiulikontsert

  16. Obama pistab vabariiklastega rinda / Hendrik Vosman

    Index Scriptorium Estoniae

    Vosman, Hendrik

    2011-01-01

    USA president Barack Obama tutvustas riigi uut säästukava, mille keskne soov on ulatuslikult parandada maksusüsteemi ja teenida nii riigikassasse 10 aasta jooksul juurde 1,5 triljonit dollarit. Seoses vabariiklaste vastuseisuga ei ole Obamal lootust pälvida Kongressis kava heakskiitu. Diagramm: Obama kava eelarvepuudujäägi vähendamiseks.

  17. Herbal medicines in the treatment of psychiatric disorders: 10-year updated review.

    Science.gov (United States)

    Sarris, Jerome

    2018-03-25

    This paper provides a 10-year update of the 2007 systematic review of herbal medicines studied in a broad range of psychiatric disorders, including depression, anxiety, obsessive-compulsive, seasonal affective, bipolar, psychotic, phobic, somatoform, and attention-deficit hyperactivity disorders. Ovid Medline, PubMed, and the Cochrane Library were searched for herbal medicines with both pharmacological and clinical evidence of psychotropic activity. This updated review now covers clinical trial evidence for 24 herbal medicines in 11 psychiatric disorders. High-quality evidence was found to exist for the use of Piper methysticum (Kava), Passiflora spp. (passionflower) and Galphimia glauca (galphimia) for anxiety disorders; and Hypericum perforatum (St John's wort) and Crocus sativus (saffron) for major depressive disorder. Other encouraging herbal medicines with preliminary evidence include Curcuma longa (turmeric) in depression, Withania somnifera (ashwagandha) in affective disorders, and Ginkgo biloba (ginkgo) as an adjunctive treatment in Schizophrenia. Although depression and anxiety are commonly researched, many other mental disorders still require further prospective investigation. Although the previous review suggested increasing the adjunctive study of select herbal medicines with pharmaceuticals, this was still only found to sparingly occur in research designs. Aside from this, future focus should involve the incorporation of more biomarker analysis, in particular pharmacogenomics, to determine genetic factors moderating response to herbal medicines. Copyright © 2018 John Wiley & Sons, Ltd.

  18. Complementary medicines (herbal and nutritional products) in the treatment of Attention Deficit Hyperactivity Disorder (ADHD): a systematic review of the evidence.

    Science.gov (United States)

    Sarris, Jerome; Kean, James; Schweitzer, Isaac; Lake, James

    2011-08-01

    Complementary and Alternative Medicines (CAMs) are frequently given to children and adolescents for reputed benefits in the treatment of hyperkinetic and concentration disorders such as Attention Deficit Hyperactivity Disorder (ADHD). In such vulnerable populations high quality evidence is required to support such claims. The aim of the paper is to assess the current evidence of herbal and nutritional interventions for ADHD using a systematic search of clinical trials meeting an acceptable standard of evidence. PubMed, PsycINFO, Cochrane Library and CINAHL were searched up to May 26th, 2011 for randomised, controlled clinical trials using CAM products as interventions to treat ADHD. A quality analysis using a purpose-designed scale, and an estimation of effect sizes (Cohen's d) where data were available, were also calculated. The review revealed that 16 studies met inclusion criteria, with predominant evidentiary support found for zinc, iron, Pinus marinus (French maritime pine bark), and a Chinese herbal formula (Ningdong); and mixed (mainly inconclusive) evidence for omega-3, and l-acetyl carnitine. Current data suggest that Ginkgo biloba (ginkgo), and Hypercium perforatum (St. John's wort) are ineffective in treating ADHD. The research suggests only some CAMs may be beneficial in ADHD, thus clinicians need to be aware of the current evidence. Promising candidates for future research include Bacopa monniera (brahmi) and Piper methysticum (kava), providing potential efficacy in improving attentional and hyperkinetic disorders via a combination of cognitive enhancing and sedative effects. Copyright © 2011 Elsevier Ltd. All rights reserved.

  19. Памяти гения русской культуры

    Index Scriptorium Estoniae

    2009-01-01

    Tallinna Slaavi Kultuuriühing tähistas 4. aprillil Vene Kultuurikeskuses Nikolai Gogoli 200. sünniaastapäeva kirjandusliku õhtuga "200 aastat Gogoliga" (kava koostasid Jevgeni Gaitšuk ja Lidia Golovataja Vene Teatrist)

  20. Memento püstitab Metsakalmistule mälestuskivi kommunismiohvritele / Küllike Rooväli

    Index Scriptorium Estoniae

    Rooväli, Küllike, 1969-

    2005-01-01

    Õigusvastaselt represseeritute liidu Memento Tallinna ühendus paigaldab Metsakalmistule mälestuskivi kommunismi ohvritele, tulevikus on ühendusel kavas rajada kommunismiohvrite memoriaal Tallinna kesklinna

  1. Õõvafestivalile andis avalöögi "Paani labürint" / Kaie Ilves

    Index Scriptorium Estoniae

    Ilves, Kaie

    2007-01-01

    PÖFFi korraldatud II õudusfilmide festival Haapsalu Kultuurikeskuses (22.-25. märtsini) algas mehhiklase Guillermo del Toro fantaasiafilmiga "Paani labürint". Ka edaspidi kavas olevatest filmidest

  2. SES Kunsti- ja Käsitööringi tegevusest / Silvia Silvéus

    Index Scriptorium Estoniae

    Silvéus, Silvia, 1926-2016

    2004-01-01

    7. veebr. 2004 toimunud peakoosolekul valiti uus juhatus, kinnitati 2003. aasta aruanded ning arutati 2004. aasta kava - olulisim on ringi töö 25. aastapäeva tähistamiseks väljaantava albumi koostamine

  3. Controversial 2008 budget passed by Cabinet / Talis Saule Archdeacon

    Index Scriptorium Estoniae

    Archdeacon, Talis Saule

    2007-01-01

    Läti valitsus kiitis erakorralisel kohtumisel heaks 2008. aasta eelarve kava ja saatis selle parlamendile. Eelarvega rahulolematust on väljendanud ka koalitsioon ja rahvuspartei Isamaa ja Vabaduse Eest

  4. Arvo Pärt ajas ja ajatuses / Igor Garšnek

    Index Scriptorium Estoniae

    Garšnek, Igor, 1958-

    2010-01-01

    Mõtteid Arvo Pärdi muusikast ajendatuna ETVs 2. septembril kavas olnud saadetest: "Arvo Pärt Istanbulis " ja "Arvo Pärdi autorikontsert Istanbulis", mis kajastasid 7. juunil Hagia Irene kirikus esiettekandel tulnud helilooja uusimat teost "Aadama itk"

  5. Druzhinniki sostavili dlja Jõhvi mozaiku / Sirle Sommer-Kalda

    Index Scriptorium Estoniae

    Sommer-Kalda, Sirle, 1974-

    2002-01-01

    Jõhvi kaubakeskuse esisel väljakul õpilasmalevlaste poolt valmistatud Virumaad kujutavast põllukividest mosaiikpannoost. Päikest kujutav mosaiik on kavas teha Ontikal. Kommenteerib projekti juht Anne Aedma

  6. Dokazatelstvo ot obratnogo / Lev Livshits

    Index Scriptorium Estoniae

    Лившиц, Лев, 1924-2013

    2008-01-01

    UNESCO maailmapärandi nimekirja kuuluva Tallinna vanalinna kaitsetsooni loomisest ja kõrghoonete ehitamisest vanalinna läheduses. UNESCO komitee nõuab vanalinna puhvertsooni loomise kava ja ülevaadet Tallinna kõrghoonete teemaplaneeringust

  7. Uudised : Kõlas eesti koorilooming. Barokk-kontsert EMAs. Interpretatsioonipedagoogika konverents. 33. Balti muusikateaduse konverents / Reet Varblane

    Index Scriptorium Estoniae

    Varblane, Reet, 1952-

    1999-01-01

    18. nov. esitas inglise koor Bristolis kava eesti muusikast. 21. nov. toimuvast barokkmuusikakontserdist EMAs. 12.-13. nov. EMAs toimunud teaduslik-metoodilisest konverentsist "Interpretatsioonipedagoogika probleemid I". 26.-28. nov. toimuva 33. Balti muusikateaduse konverentsi kavast

  8. Sügiskonverents "Kunst paguluses"...

    Index Scriptorium Estoniae

    2008-01-01

    28. VIII Kumu Kunstimuuseumi auditooriumis toimuva konverentsi kava. Esinevad Jaan Undusk, Piret Kruuspere, Avo Hirvesoo, Mara Lace, Osvaldas Daugelis, Piret Noorhani, Irja Bergström, Tiiu Talvistu ja Kersti Koll

  9. Sotsialistlik filmiavangard / Lauri Kärk

    Index Scriptorium Estoniae

    Kärk, Lauri, 1954-

    2008-01-01

    XXX Moskva rahvusvahelise filmifestivali kavas oli ka läbilõige "sotsialistlikust avangardismist". 1920-ndate nõukogude avangardismist ja selle suurimast väärtusest kinokunsti arengusse - montaažist

  10. Rahvusvaheline rongiliiklus on tõusev trend / Silvia Pärmann

    Index Scriptorium Estoniae

    Pärmann, Silvia

    2007-01-01

    Eesti Raudtee plaanib investeeringuid raudtee reisijasõbralikumaks muutmiseks: kavas on tõsta liikluskiirust kogu raudtee ulatuses 120 kilomeetrini tunnis, lisada reisironge Peterburi suunal ning luua rongiühendus Riiaga. Tabel: Luksuslik rongisõit Imperaatori salongis

  11. Uhiuus orkester Tallinn Sinfonietta / Ivo Lille ja Risto Joost ; intervjueerinud Kristina Kõrver

    Index Scriptorium Estoniae

    Lille, Ivo, 1977-

    2009-01-01

    Kontserdiagentuurist HIMusic Agency ja Tallinn Sinfoniettast räägivad dirigent R. Joost ja I. Lille. Avakontserdist Vene Kultuurikeskuses, kus oli kavas Mozarti sümfooniad 1, 10 ja 40 ning kontsertaariad bulgaaria soprani Sonya Youncheva esituses

  12. Eesti kultuurielu suursündmus Berliinis / Vardo Rumessen

    Index Scriptorium Estoniae

    Rumessen, Vardo, 1942-2015

    2011-01-01

    15. aprillil Berliini Filharmoonia suures saalis toimunud Deutsches Symphonie-Orchester Berlin kontserdist Neeme Järvi dirigeerimisel, kus oli kavas ka Tubina Sümfoonia nr 5. Neeme Järvi lähituleviku plaanidest

  13. Suvemuusika / Igor Garshnek

    Index Scriptorium Estoniae

    Garšnek, Igor, 1958-

    2000-01-01

    Pärnu "Raemuusika" festivali kontsertidest Tallinnas ئ 15. aug. Estonia kontserdisaalis Performers of the Royal Opera House, kavas Mendelssohni Oktett ja Vivaldi "Aastaajad"; 21. aug. Oleviste kirikus J. Taveneri teose "Ultimos ritos" ettekanne

  14. Külalised ja meie / Tiiu Levald

    Index Scriptorium Estoniae

    Levald, Tiiu, 1940-

    2009-01-01

    11. detsembril Estonia kontserdisaalis toimunud ERSO kontserdist, dir. Olari Elts ja solist soome metsosopran Monica Groop, kavas oli Wagneri ja Mendelssohni looming ning 12. detsembril Estonias toimunud Donizetti ooperi "Poliuto" kontsertettekandest, dirigent Arvo Volmer

  15. Berliini filmifestivalil näeb ka Peeter Simmi filmi "Head käed" / Triin Tael

    Index Scriptorium Estoniae

    Tael, Triin

    2002-01-01

    Berliini 52. filmifestival algas eile sakslase Tom Tykweri mängufilmiga "Taevas". Esmakordselt on festivali "Panorama" kavas eesti mängufilm, milleks on Peeter Simmi "Head käed". Eesti filmid on esil ka festivali suurel filmiturul

  16. Kunstitarbimisorgia kunstlikult põhjamaises suvitusrajoonis / Mari Sobolev

    Index Scriptorium Estoniae

    Sobolev, Mari, 1968-

    2004-01-01

    Jaan Toomiku ja Paul Rodgersi organiseeritud tegevuskunsti festivalist "Viinistu 2004", kavas performance'id, installatsioonid, video, näitused. Pikemalt Steven Coheni, Elu, Neeme Külma, Minna Hindi, Erik Alalooga esinemisest

  17. Kas offshore on riigile kasulik või kahjulik? / Ivo Vanasaun

    Index Scriptorium Estoniae

    Vanasaun, Ivo

    2003-01-01

    Autor vastab küsimustele, kuidas offshore'i ära tunda, miks Eesti ei ole madala maksumääraga piirkond ning missugused maksumuudatused on kavas seoses offshore'i piirkonnas registreeritud ettevõtetega

  18. 19. ja 20. IV toimub Tartu kõrgemas kunstikoolis...

    Index Scriptorium Estoniae

    2002-01-01

    Konverentsi "Sharing the Future?", mis on pühendatud foto ja uue meedia hariduse küsimustele endises Ida-Euroopas, kava. Inglise fotograafi Robin Dance'i isiknäitus "Jaapani maastikud" Sebra galeriis

  19. Rice vaikib salavanglaist / Tõnis Erilaid

    Index Scriptorium Estoniae

    Erilaid, Tõnis, 1943-

    2005-01-01

    Euroopasse visiidile sõitev USA välisminister Condoleezza Rice külastab Saksamaad, Rumeeniat, Ukrainat ja Belgiat. Süüdistusi CIA lennukite maandumiste ja salavanglate kohta ei olevat tal kavas kommenteerida

  20. Eesti film vaimustas Berliini festivali kinoasjatundjaid / Karlo Funk

    Index Scriptorium Estoniae

    Funk, Karlo, 1971-

    2002-01-01

    Berliini 52. filmifestivali "Panorama Special" kavas olnud Peeter Simmi Eesti-Läti ühisfilm "Head käed" saavutas hea publikuedu saksa kinoprofessionaalide hulgas ja leidis ka kriitkas positiivset vastukaja

  1. Berlinale tõstab Ladina-Ameerikat / Andres Laasik

    Index Scriptorium Estoniae

    Laasik, Andres, 1960-2016

    2004-01-01

    Berliini filmifestivalist, mis sel aastal algab 5. veebruaril. Avafilmiks on Anthony Minghella "Külm mägi" ("Cold Mountain) : Ameerika Ühendriigid. Saksa ja Ladina-Ameerika filmidest festivali kavas

  2. Noorpianist pani "tundmatu" Elleri plaadile / Sten Lassmann ; intervjueerinud Mart Niineste

    Index Scriptorium Estoniae

    Lassmann, Sten, 1982-

    2011-01-01

    Vestlus pianistiga Londoni Kuninglikus Muusikaakadeemias õppiva pianistiga, tema doktoritööst. Plaadifirma Toccata Classics poolt väljaantavast Heino Elleri klaverimuusika heliplaadist, kavas välja anda seitse heliplaati

  3. Sten Lassmann uurib ja plaadistab Ellerit

    Index Scriptorium Estoniae

    2011-01-01

    Londoni Kuninglikus Muusikaakadeemias õppivast pianistist, tema doktoritööst. Plaadifirma Toccata Classics poolt väljaantavast Heino Elleri klaverimuusika heliplaadist, kavas välja anda seitse heliplaati

  4. Enron ja terrorirünnakud aitasid Eestit / Sulev Vedler

    Index Scriptorium Estoniae

    Vedler, Sulev, 1970-

    2006-01-01

    USA hiidfirma Enron krahh ja terrorirünnakud New Yorgi kaksiktornile ajasid nurja Eesti valitsuse kava erastada Narva elektrijaamad USA firmale NRG Energy. USA kompanii eelistamine ei tagaks julgeolekut. Diagramm: NRG tõuseb jalule

  5. Nähtamatud lapsed / Margit Tõnson

    Index Scriptorium Estoniae

    Tõnson, Margit, 1978-

    2006-01-01

    UNICEFi palvel valmistasid kaheksa tuntud režissööri kassett-filmi maailma kannatavatest lastest "Kõik nähtamatud lapsed" ("All the Invisible Children") : Prantsusmaa - Itaalia 2005. Film on Sõpruse kino kavas

  6. Uudised : Tüür ja Kaljuste Amsterdamis

    Index Scriptorium Estoniae

    2006-01-01

    Kontserdil 22. mail Amsterdamis dirigeerib Tõnu Kaljuste Madalmaade Kammerkoori. Kavas Mauricio Kageli ja Gia Kantsheli teoste kõrval ka Erkki-Sven Tüüri "The Wanderer's Evening Song" ja "Meditatio"

  7. Welcome to Denmark! / Eiki Nestor

    Index Scriptorium Estoniae

    Nestor, Eiki, 1953-

    2005-01-01

    Kuigi meie poliitikud toovad eeskujuks Taani paindliku tööturu, viib Eesti valitsuse kava autori sõnul pigem Bangladeshi kui Taani suunas. Autor selgitab, mis meid Taanist selles valdkonnas eristab

  8. Деньги есть, умов бы надо / Мадис Эйнасто ; интервьюировала Анастасия Тидо

    Index Scriptorium Estoniae

    Эйнасто, Мадис

    2011-01-01

    Valitsus on heaks kiitnud teadusinvesteeringute kava. Teiste hulgas toetust saava Evikon MCI juht räägib ettevõtte koostööst teaduskollektiividega, teadusarengust ja tänapäeva probleemidest Eesti teaduses

  9. Suupillineiu edu valem on "koerahingamises" / Ragne Jõerand

    Index Scriptorium Estoniae

    Jõerand, Ragne, 1970-

    2006-01-01

    Pärnu-Jaagupi muusikakoolis õpetaja Ilmar Tõnissoni käe all õppivast suupillimängijast Melani Talist. V Pärnu rahvusvahelise suupillifestivali "Baltic-Nordic Harmonica 2006" kava 28.-30. juulini

  10. XXI Pärnu filmifestival tuleb valikkavaga / Lii Bärlin

    Index Scriptorium Estoniae

    Bärlin, Lii

    2007-01-01

    24. ja 25. juulil näidatakse huvilistele Rakvere Teatrikinos XXI Pärnu filmifestivali raames filmide valikkava. Filme soovitavad Mark Soosaar, Rakvere Teatrikino projektijuht Jaanus Kaasik. Lisatud filmide kava

  11. Lithuania defends currency / Adam Mullett

    Index Scriptorium Estoniae

    Mullett, Adam

    2009-01-01

    Leedulased kiirustavad oma pangasäästusid vahetama eurode vastu, kuna kardetakse raha devalveerimist. Valitsus aga kinnitab, et vaatamata Leedu pangandussektoris esinevatele probleemidele pole lähiajal devalveerimist kavas

  12. Kõusaare film pääses Cannes'i programmi

    Index Scriptorium Estoniae

    2007-01-01

    Cannes'i filmifestivali kavas "Un certain regard" on tänavu ka Kadri Kõusaare mängufilm "Magnus" : produtsent Donal Fernandes : operaator Pawel Sobczyk : osades Kristjan Kasearu, Ruuben Rekkor : Eesti (Vitamin K Film) - Suurbritannia (Donus Films Limited)

  13. SDE seisab uute põlevkivikaevanduste vastu / Piret Pert

    Index Scriptorium Estoniae

    Pert, Piret

    2006-01-01

    SDE tutvustas pressikonverentsil oma keskkonnapoliitilisi seisukohti. Sotsiaaldemokraadid on vastu uute põlevkivikaevanduste avamisele enne olemasolevate ammendumist, SDE eelnõu kohaselt tuleks uute kaevanduste avamiste kava kinnitamisele Riigikogus

  14. Andrus Ansip seadis Tallinna-Tartu maantee riigi prioriteetide hulka / Tuuli Koch

    Index Scriptorium Estoniae

    Koch, Tuuli, 1978-

    2006-01-01

    Peaminister Andrus Ansip sõnas Riigikogu infotunnis, et Tallinn-Tartu maantee on olnud riigi jaoks prioriteet ning aastani 2013 Euroopa Liidu struktuurifondidest Eestile laekuvast 52 miljardist kroonist on riigil kavas Tartu maanteesse investeerida 4,5 miljardit krooni

  15. Aafrikast ei leitud ühtegi preemiaväärilist riigipead

    Index Scriptorium Estoniae

    2009-01-01

    Briti miljardäri Mo Ibrahimi preemia Aafrika riigipeale jäi tänavu välja andmata, temanimelisel fondil on kavas korraldada Tansaanias konverents, kus rõhutatakse hea valitsemise vajadust Mustal Mandril

  16. Geroi komiksa : so stranits - na ekranõ / Oleg Nikolajev

    Index Scriptorium Estoniae

    Nikolajev, Oleg

    2000-01-01

    Koomiksite jõudmisest kinoekraanidele. Mängufilm "X-mehed" ("X-Men") oli esimene kirjastuse Marvel Comics poolt väljaantud koomiksi põhjal tehtud film. Kavas on Hollywoodil neid praegu vähemalt 12

  17. Polymeri utoopiline festival meelitab uue maailma kunstnikke / Sandra Jõgeva ; intervjueerinud Mari Peegel

    Index Scriptorium Estoniae

    Jõgeva, Sandra, 1976-

    2011-01-01

    Festivali kava üks koostajaid Sandra Jõgeva 24.-28. augustini 2011 toimuvast kultuuritehase Polymer festivalist ja tähtsamatest esinejatest. Selle aasta festivalil tegeldakse utoopiliste visioonidega

  18. JAFF rebib akna alternatiivmaailmadesse

    Index Scriptorium Estoniae

    2011-01-01

    Tallinna ja Tartu kinodes 15.-24. aprillini toimuva 5. Jaapani animatsiooni filmifestivali JAFF kavast. JAFF-i teemaks on ookean. Fookuses on animemeister Satoshi Kon, festivali kavas on neli tema filmi

  19. Laval ja põrandal / Mart Siimer

    Index Scriptorium Estoniae

    Siimer, Mart

    1999-01-01

    23. augustil Estonia kontserdisaalis toimunud kammerkontserdist "Lootuste lõppematus". Kavas M. Tally "Kaks vaadet merele", T. Trassi "Psalmid" ja T. Tulevi "Sin otra luz". 25. augustil Estonia kontserdisaalis toimunud Birmingami SO kontserdist

  20. Riik plaanib haiglatele anda õiguse ka arstirohtu müüa / Andrus Karnau

    Index Scriptorium Estoniae

    Karnau, Andrus

    2006-01-01

    Vt. ka Postimees : na russkom jazõke 31. märts lk. 3. Riik tahab anda haiglatele õiguse pidada jaemüügirohupoode, selle kava vastu on aga konkureerivad apteegiketid, konkurentsi- ja ravimiamet. Lisa: Ketistunud apteegiturg

  1. Lugupeetud kunstnikud, arhitektid ja sõbrad!

    Index Scriptorium Estoniae

    2001-01-01

    Eesti Kunstnike Liidu ja Eesti Arhitektide Liidu aastavahetuspeo kava 28. XII. Esinevad Raivo Kelomees (EKA ja Tartu Kõrgema Kunstikooli videoprojektid), EKA moeosakond. Nova Moda esitleb: Ruta Depp, Ketlin Bachman, Riina Põldroos, Kati Simpson

  2. Festival lähetab maailma eri nurkadesse / Kerttu Jänese

    Index Scriptorium Estoniae

    Jänese, Kerttu, 1946-

    2008-01-01

    V dokumentaal- ja antropoloogiliste filmide festival "Maailmafilm" algab 24. märtsil Eesti Rahva Muuseumi näitusemajas Tartus. Kavas on ka kolm eriprogrammi: kirjanikud filmis, klassiku Timothy Aschi looming ja 8 filmi inimesest linnas

  3. Enlarged Liver

    Science.gov (United States)

    ... of liver damage. Medicinal herbs. Certain herbs, including comfrey, ma huang and mistletoe, can increase your risk ... herbs to avoid include germander, chaparral, senna, mistletoe, comfrey, ma huang, valerian root, kava, celandine and green ...

  4. Obama alustab külaskäiku Venemaale keerulisel ajal / Liisi Poll

    Index Scriptorium Estoniae

    Poll, Liisi, 1980-

    2009-01-01

    USA president Barack Obama alustab 6. juulil oma Moskva visiiti, mille käigus on tal kavas lisaks Kremli juhtidele kohtuda ka opositioonitegelaste ning Nõukogude Liidu viimase juhi Mihhali Gorbatšoviga

  5. 40 CFR 180.472 - Imidacloprid; tolerances for residues.

    Science.gov (United States)

    2010-07-01

    ... 1.5 Grape, raisin 1.5 Guava 1.0 Herbs subgroup 19A, dried herbs 48 Herbs subgroup 19-A, fresh herbs... Kava, leaves 4.0 Kava, roots 0.40 Leaf petioles subgroup 4B 6.0 Leafy greens subgroup 4A 3.5 Lettuce, head 3.5 Lettuce, leaf 3.5 Lingonberry 3.5 Longan 3.0 Lychee 3.0 Mango 1.0 Milk 0.10 Mustard, black...

  6. Pärnu on Eesti funktsionalismi lipulaev / Anu Villmann

    Index Scriptorium Estoniae

    Villmann, Anu

    2006-01-01

    Pärnu uusehitistest - Seedri tänava elamud (arhitekt Kalle Vellevoog), kortermaja Tammsaare ja Lehe tänava nurgal (arhitekt Tanel Tuhal arhitektuuribüroost Luhse ja Tuhal) ja kesklinna koolide võimla (arhitektid Katrin Koov, Siiri Vallner, Kaire Nõmm ja Heidi Urb arhitektuuribüroost KAVA KAVA). Pärnu arhitektuurist võtavad sõna Pärnu Linnavalitsuse arhitekt Karri Tiigisoon, Helle-Ann Urgard, Tanel Tuhal, Hardi Lehemaa ja Toomas Unt

  7. Kontserdipeegel / Evi Arujärv

    Index Scriptorium Estoniae

    Arujärv, Evi, 1953-

    2002-01-01

    16. apr. Tallinna raekojas kontserdisarjas "Upbeat" esinesid läti noored muusikud. 20. apr. kontserdisarja "Euroopa tippsoliste" viimasel kontserdil esines koos Estonia sümfooniaorkestriga norra vioolamängija Lars-Anders Tomter. 19. apr. mängis Nyyd Ensemble Kanuti gildi saalis Mauricio Kageli kava, kus kaasa tegid ka Von Krahli teatri näitlejad. 21. apr. oli Eesti Filharmoonia Kammerkoori ja Tallinna Kammerorkestri ees taas Tõnu Kaljuste ja seekord olid kavas missad

  8. Pronksmees, propaganda ja kodanikuühiskond / Kaspar Näf

    Index Scriptorium Estoniae

    Näf, Kaspar

    2007-01-01

    Pronkssõduri teisaldamisega seoses Tallinnas toimunud tänavarahutuste ühistest joontest Šveitsis ja Venemaal toimunuga, apoliitilise massi käitumisest, Venemaa propagandast ja juhitud demokraatiast. Autori arvates meenutab Eesti valitsuse kodanikuühiskonna loomise kava Venemaa presidendi kava ning ütleb, et kodanikuühiskonda ei saa luua ükski valitsus, vaid see kasvab ise.

  9. Riik kavandab peremaju erivajadustega inimestele / Anu Jürisson

    Index Scriptorium Estoniae

    Jürisson, Anu

    2006-01-01

    Sotsiaalministeeriumil on kavas koostöös maavalitsustega korraldada lähikümnendil ümber senine erihoolekanne. Pärnumaal on kavas luua AS-i Medici baasil riiklik AS Hoolekanne, mis võtab üle kõik psüühiliste erivajadustega inimestele ööpäev läbi hoolekandeteenust pakkuvad asutused, mille hooneist ebasobivate asemele ehitatakse uued

  10. Plantas medicinais no tratamento do transtorno de ansiedade generalizada: uma revisão dos estudos clínicos controlados Medicinal plants for the treatment of generalized anxiety disorder: a review of controlled clinical studies

    Directory of Open Access Journals (Sweden)

    Thalita Thais Faustino

    2010-12-01

    Full Text Available OBJETIVO: Revisar os estudos clínicos controlados sobre a efetividade de plantas medicinais/fitoterápicos no transtorno de ansiedade generalizada. MÉTODO: Realizou-se uma busca (Medline, Web of Science, SciELO, Biblioteca Cochrane por artigos originais utilizando as palavras ["plant OR phytomed* OR extract OR herbal OR medicinal (OR specific name plants"] AND ("anxie* OR anxioly* OR tranquil* OR GAD", delimitada a "human OR clinical trial OR randomized controlled trial OR meta-analysis OR review" e à língua inglesa. Os critérios de inclusão foram: estudos randomizados, comparativos e duplo-cegos. RESULTADOS: Foram selecionados sete dos 267 artigos encontrados. O Piper methysticum (kava-kava foi o fitoterápico mais estudado, sendo sugerido um efeito ansiolítico. Entretanto, a maioria destes estudos incluiu outros transtornos de ansiedade e os dois estudos com transtorno de ansiedade generalizada apresentaram resultados contraditórios. Estudos isolados envolvendo Ginkgo biloba, Galphimia glauca, Matricaria recutita (camomila, Passiflora incarnata e Valeriana officinalis indicaram potencial efeito ansiolítico no transtorno de ansiedade generalizada. A Ginkgo biloba e a Matricaria recutita apresentaram um effect size ('d' de Cohen = 0,47 e 0,87 similar ou superior ao dos ansiolíticos atuais (0,17-0,38. Não foram localizados estudos com outras plantas. CONCLUSÃO: Apesar do potencial terapêutico dos fitoterápicos no transtorno de ansiedade generalizada, poucos ensaios clínicos controlados foram identificados, com a maioria apresentando limitações metodológicas.OBJECTIVE: This work aimed to identify controlled trials, which evaluated effectiveness of herbal medicines in subjects suffering generalized anxiety disorder. METHOD: Controlled studies (randomized, comparative with placebo and/or standard drug, double-blind were sought through electronic and hand-searches. The word strategy used "plant OR phytomed* OR extract OR herbal OR

  11. Updates on Nutraceutical Sleep Therapeutics and Investigational Research

    Directory of Open Access Journals (Sweden)

    Michael Yurcheshen

    2015-01-01

    Full Text Available Approximately 50% of the population will suffer from a sleep disorder over the course of their lifetime. There is increasing interest in nutraceuticals for these conditions. The quality of the evidence for the safety and effectiveness of using these supplements to treat sleep disorders varies substantially. In this review, we discuss the data about the effectiveness and safety of six commonly used plant-based sleep therapeutics: caffeine, chamomile, cherries, kava kava, L-tryptophan, marijuana, and valerian. We explore both historical uses of each substance and the current state of the literature.

  12. 19. novembril avati Eesti Kunstiakadeemia aulas...

    Index Scriptorium Estoniae

    1998-01-01

    Prantsusmaa, Balti- ja Põhjamaade video ja uue meedia festival "offline@online". Festivali osad : videod ja eksperimentaalne film ning online-videod, võrguprojektid, CD-ROMid. Osa võtavad rahvusvaheliselt tuntud kunstnikud ja lektorid. Üldkuraator Raivo Kelomees, võrguprojektide kuraator Tiia Johannson. Ürituste kava 20. ja 21. novembril.

  13. Uudised : Tormis ja Pärt esiettekandel EXPO-l. Eesti muusika EXPO-l. Eesti muusikat Jaapanis / Priit Kuusk

    Index Scriptorium Estoniae

    Kuusk, Priit, 1938-

    2000-01-01

    2. sept. Hannoveri maailmanäituse EXPO kultuuriprogrammi raames toimunud uue koorimuusika esitluskontserdist "Sieben Exponaten", kus olid kavas ka A.Pärdi ja V.Tormise teosed. Eesti muusikute esinemisest maailmanäitusel EXPO 2000 Hannoveris. Tokyo FK andis 27. aug. Tokyos kontserdi eesti ja soome muusikast

  14. Punane süda mustal lipul / Lauri Kaare

    Index Scriptorium Estoniae

    Kaare, Lauri

    2004-01-01

    Helsingis 17. korda toimuva festivali "Armastus ja Anarhia" kavas olnud filmidest - korealase Park Chan-Wooki "Vanapoiss" ("Old Boy"), Richard Linklateri "Enne päikeseloojangut" ("Before Sunset"), india film "Homne võib jööda tulemata" ("Tomorrow May Never Come"), mehhiko "Nikotiin" ("Nicotina") jt

  15. MTVP riskirahaga ehitatakse Rate'ist Euroopa turuliidrit / Raigo Neudorf

    Index Scriptorium Estoniae

    Neudorf, Raigo

    2007-01-01

    Riskikapitalifirma Martinson Trigon Venture Partners (MTVP) eesmärk on kasvatada suhtlusportaali Rate.ee omanikefirma Rate Solutions üheks Euroopa juhtivaks tegijaks omas valdkonnas. Lisad: Martinson suunas fondi 7 miljonit; Ka kirjavigade pealt saab teenida; Martinsonil ja Trigonil oli kavas riskikapitalifirma luua juba 1999. aastal

  16. Klas puts imprint on 'signature piece' / Herman Trotter

    Index Scriptorium Estoniae

    Trotter, Herman

    1996-01-01

    Kontserdiarvustus. Buffalo Philharmonic Orchestra, külalisdirigent Eri Klas, solist Arie Lipsky (tšello). Kavas: D. Šostakovitš, Sümfoonia nr. 5; E. Dohnanyi, Konzertstück tšellole ja orkestrile ja W. A. Mozart, Divertisment keelpilliorkestrile, KV 136, D-duur

  17. Esietendused

    Index Scriptorium Estoniae

    2001-01-01

    Hendrik Toompere jun. lavastatud Boguslaw Schaefferi "SiinSeal" Eesti Draamateatri väikeses saalis. Nukuteatri ovaalsaalis Ferdinand Veike kava "Ferdinand Veike ja Lilleprintsess". Rakvere Teatris prantsuse näitekirjaniku Eric-Emmanuel Schmitti "Kahe maailma hotell". Vanalinnastuudios Trevor Griffithsi komöödia "Koomikud"

  18. Täna läheb käima suveteatrimaraton / Meelis Kapstas

    Index Scriptorium Estoniae

    Kapstas, Meelis, 1963-

    2000-01-01

    Eesti teatrite suvelavastustest - "Väike õuduste pood", "Save Our Souls", Meil aiaäärne tänavas", "Surm ooperis", "Aristokraadid", "Huck", "Leonce ja Lena" ja "Armastajad kurja tähe all".Lisatud suveteatri lavastajate - Merle Karusoo, Evald Hermaküla, Ain Prosa ja Georg Malviuse - saatesõnad oma lavastustele. Samuti lisatud suvelavastuste kava

  19. Looma koht on džunglis, inimese koht tsirkuselaval / Kaarel Kressa

    Index Scriptorium Estoniae

    Kressa, Kaarel, 1983-

    2011-01-01

    5.-13.08.2011 Tallinnas Kadrioru pargis ja Kumu auditooriumis esimest korda toimuvast rahvusvahelisest uue tsirkuse festivalist "Tsirkusepuu". Sebastiano Toma oma trupi The Time Between Company lavastusest "The Time Between", traditsioonilise ja tänapäevase tsirkuse erinevusest. Festivali kava

  20. Katariina kirikus algab Geeniuste mäss / Kai Ilustrumm

    Index Scriptorium Estoniae

    Ilustrumm, Kai

    2004-01-01

    Briti Nõukogu toetusel Pärnus, Tartus ja Tallinnas toimuvatel inglise filmide päevadel "Geeniuste mäss" näidatakse ka 3 Lindsay Andersoni nn. Travise triloogia filmi "Kui..." (1968), "Oo, õnneseen!" (1973) ja "Ravila Britannia" (1982), kus Mick Travise rollis on Malcolm McDowell (1943). Lisatud kava

  1. Rüütliga kohtunud Ivanov lubas tänavu Eestisse tulla

    Index Scriptorium Estoniae

    2003-01-01

    Ilmunud ka Postimees (2003/Sep/24) lk. 3. President Arnold Rüütliga New Yorgis kohtunud Venemaa välisminister Igor Ivanov kinnitas, et tal on kavas Eestisse visiidile tulla. Töövisiit New Yorki 20.-26.09.2003

  2. Eesti kunstimaailm... / Ivika Kivi ; interv. R[eet] V[arblane

    Index Scriptorium Estoniae

    Kivi, Ivika

    2007-01-01

    Uus kuraator Ivika Kivi Grazi meediakunsti laborist, kus 3. IV avati Mare Tralla näitus "Her. Space", kuraatori võimalustest ja labori tulevikuplaanidest. Kavas on Piret Räni näitus "Hello Friend, Are You Impotent" (avamisel naiskunstnike seltsi Puhas Rõõm performance) ja Eve Kiileri näitus "Everyman Time Machine"

  3. Kultuuripealinn kutsub sel nädalal tundmatuid katuseid käima / Heidi Kukk

    Index Scriptorium Estoniae

    Kukk, Heidi

    2010-01-01

    Tallinn 2011 ootussarja "52 üllatust ja ideed" raames 12. ja 13. augustil toimuvast projektist "Katustele", mille eestvedajateks on Eesti Kunstiakadeemia üliõpilased Helen Melesk ja Hello Upan. Järgmisena on kavas tantsu- ja laululine performance Anneli Leinbergi juhendamisel ja Tallinna merepiiri kasutule olekule pühendatud kunstiprojekt "Bassein"

  4. Uudised : Muusikafestival Hiiumaal. Spirituaalide õhtu Joseph Jenningsiga. Teised meist

    Index Scriptorium Estoniae

    2001-01-01

    13.-15. juulini toimuvatest III Hiiumaa kammermuusikapäevadest. EFK esitab J.Jenningsi juhatusel Pärnus, Tallinnas ja Kuressaares spirituaalide kava. Venemaa Heliloojate Liidu väljaandes Rossiiskaja Muzõkalnaja Gazeta (nr. 5/ 2001) ilmus A. Grigorjeva artikkel tänavustest eesti muusika päevadest

  5. Jasper Sharp - mees, kes jättis varasema töö, et vaadata Jaapani filme / Jasper Sharp ; intervjueerinud Helen Merila

    Index Scriptorium Estoniae

    Sharp, Jasper, 1971-

    2011-01-01

    Euroopa kultuuripealinn Tallinn 2011 programmi osana ning koostöös Zipangu Fest'iga korraldatakse Tallinna Kinomajas 25.-28. aug.-ni Aasia sõltumatute filmide festival EVA - East via Asia. Festivali kuraator, veebisaidi Midnight Eye kaastoimetaja Jasper Sharp endast, festivalist, Jaapani sõltumatust kinost tänapäeval. Festivali kava

  6. Uned, mida mujal ei näe / Heilika Võsu ; interv. Mari Laaniste

    Index Scriptorium Estoniae

    Võsu, Heilika

    2007-01-01

    PÖFFi animafilmide festivali "Animated Dreams" (21.-25. XI kinos Sõprus), mis on seekord pühendatud Nukufilmi 50. juubelile, tutvustab festivali peakorraldaja. Võistluskavas on Eestist Kaspar Jancise "Maraton" ja Mari-Liis Bassovskaja - Jelena Girlini "Kleit". Lisatud festivali kava

  7. ETV tähistab tantsupäeva kolme filmiga

    Index Scriptorium Estoniae

    2006-01-01

    Rahvusvahelise tantsupäeva puhul 29. apr. on Eesti Televisiooni kavas kolm tantsuprogrammi - Uwe Scholzi tantsulavastus "Suur Missa", tantsufilm "Teine" (filmi režissöör René Vilbre) ja kolmas film on Inglismaal valminud Lloyd Newsoni "Elu hind"

  8. Särav Fauni pärastlõuna / Märt Treier

    Index Scriptorium Estoniae

    Treier, Märt, 1975-

    1998-01-01

    Sari "Klassika pärle" Estonia'kontserdisaalis 29.jaanuaril.Kavas C. Debussy 'Fauni pärastlõuna', C. Saint-Saensi Tshellokontsert nr.1 a-moll, O.Respighi 'Rooma purskaevud' ja I. Stravinski Süit balletist "Tulilind".Esit ERSO, Dir Andrei Tshistjakov

  9. Res Publica seisab vastu homse arvel elamisele / Siim Männik

    Index Scriptorium Estoniae

    Männik, Siim

    2005-01-01

    Ilmunud ka: Vabariik (venek.) 30. august lk. 1. Res Publica koostab praegu kohalikeks valimisteks nimekirju. Erakond ei plaani korraldada mitte ühte üleriigilist valimiskampaaniat, vaid 120 kohalikku kampaaniat, peale selle on kavas üleriigiline n.-ö. foonikampaania. Lisa: Miks valida Res Publica? Vt. samas: Sisevalimised 1.-3. septembrini

  10. Anneli Remme soovitab : Eesti Muusika Päevad 2005 / Anneli Remme

    Index Scriptorium Estoniae

    Remme, Anneli, 1968-

    2005-01-01

    Eesti Muusika Päevadest 2005: 7.-14. apr. Estonia kontserdisaalis, Viru Keskuses, Eesti Teatri- ja Muusikamuuseumis, Rahvusooperis Estonia, Õpetajate majas, Eesti Muusikaakadeemias, vanalinna tänavatel, Kinomajas, Stereo Lounge'is, Kanuti Gildi saalis, Eesti Kunstiakadeemias ja Metodisti kirikus (festivali peaheliloojaks valiti Arvo Pärt, autorikontsert tuleb Eino Tambergilt). Festivali kava: www.helilooja.ee

  11. Tüüri ava(sta)mas, kuid mitte ainult / Igor Garšnek

    Index Scriptorium Estoniae

    Garšnek, Igor, 1958-

    2011-01-01

    Kahest kontserdist Estonia kontserdisaalis - 4. märtsil ERSO ja Herbert Schuch (klaver) Olari Eltsi dirigeerimisel, kavas Tüüri Sümfoonia nr 8, Pärdi "Nekroloog" ja Ullmanni Klaverikontsert ning 10. märtsil Erkki-Sven Tüüri autorikontsert, kus esinesid Eesti Filharmoonia Kammerkoor ja Sinfonietta Riga Daniel Reussi juhatusel

  12. Eelproov Musikvereinile ja "Turangalila-sümfoonia" / Igor Garšnek

    Index Scriptorium Estoniae

    Garšnek, Igor, 1958-

    2010-01-01

    Tallinna Filharmoonia hooaja avakontserdist 6. oktoobril Estonia kontserdisaalis, kus esinesid Tallinna Filharmoonikud ja Lisa Smirnova (klaver) Andres Mustoneni dirigeerimisel ja 8. oktoobril samas toimunud ERSO kontserdist Nikolai Aleksejevi dirigeerimisel, kavas Olivier Messiaeni "Turangalila-Sümfoonia", solistid Francois Weigel ja Thomas Bloch

  13. Ameerika 11. septembri haavad hakkavad tasapisi kinni kasvama / Neeme Raud

    Index Scriptorium Estoniae

    Raud, Neeme, 1969-

    2007-01-01

    Ilmunud ka: Postimees : na russkom jazõke, 11. sept. 2007, lk. 7. 2001. aastal 11. septembril toimunud New Yorgi kaksiktornide ründamisest ja kavas olevast mälestustseremooniast. Lisa: 541-meetrine vabadustorn; 2001. aasta 11. september sünnitas rea veriseid sündmusi

  14. Tallinna ühistransport muutub kasutajasõbralikumaks / Tiit Laiksoo

    Index Scriptorium Estoniae

    Laiksoo, Tiit

    2007-01-01

    Tallinna osalemisest Euroopa Liidu projektis SMILE (towards Sustainable MobIlity for peopLe in urban arEas), mille abil töötatakse Tallinnas välja ühistranspordi eelistussüsteemi rakendamise kava ning parandatakse sõitjate teeninduse kvaliteeti

  15. Eesti Energia börsile! Argus riputaks ta meile kiviks kaela / Raimo Poom

    Index Scriptorium Estoniae

    Poom, Raimo

    2010-01-01

    Eesti Energia võimalikust börsileviimisest. Autori sõnul poleks börsikavagi täieliku riskita, peaküsimus võib hakata puudutama nn. rahvaaktsia kava. Kõige halvem oleks Eesti Energia puhul otsustamatus

  16. Muusikamaailm : Uusooper täna Houstonis. Budapesti kevadfestivalil. Müncheni linna muusikapreemia. Lauljate "Orfeo" Hannoveris. Oslo saab uue ooperimaja / Priit Kuusk

    Index Scriptorium Estoniae

    Kuusk, Priit, 1938-

    2000-01-01

    G. Floydi ooperite "Cold Sassy Tree" ja "Susannah" lavastustest Houstonis USAs. Budapesti kevadfestivalil toimub P. Eötvösi ooperi "Kolm õde" esmalavastus Ungaris. Tänavu pälvis Müncheni linna muusikapreemia Müncheni Kammerorkester. Rahvusvahelise lauljate konkursi "Orfeo 2000" võitjatest. Oslo uus ooperimaja valmib kava kohaselt 2007. aastal

  17. Plantadores de cidade ehk linnaistutajad : Millennium Village, Briti elamuehituse suurprojekt / Tõnu Laigu

    Index Scriptorium Estoniae

    Laigu, Tõnu

    2002-01-01

    Greenwich Peninsula arendamine. Üldplaneering büroolt Richard Rodgers Partnership. Millennium Village'i, mis on kavas välja arendada 2005. aastaks, planeeringu ja ala ruumilise ettepaneku koostas arhitekt Ralph Erskine koostöös bürooga Hunt Thompson Architects. Ehitatud on R. Erskine 100 korteriga elamu ja arhitekt Proctor Matthews'i lintmajad

  18. Christo kuldab Manhattani vaateid / Johannes Saar

    Index Scriptorium Estoniae

    Saar, Johannes, 1965-

    2005-01-01

    Gabrovost pärit prantsuse-ameerika kunstniku Christo (Christo Vladimirov Javacheff) ja tema kaasa Jeanne-Claude'i (Jeanne-Claude de Guillebon) projekt "Väravad" New Yorgi Central Park'is. Kunstnikepaaril on kavas palistada kõik pargirajad viie meetri kõrguste väravaraamistikega, millel ripuvad kirkad oranzhid kangad. Toimumisaeg 12.-27. veebruar 2005

  19. Uudised : Eesti esiettekandeid Eesti Filharmoonia Kammerkoorilt. Morgensterni muusikatunnid. Estonia operetisolistid Nõmmel / Avo Suurvärav

    Index Scriptorium Estoniae

    Suurvärav, Avo

    2001-01-01

    7. ja 9. apr. Tallinna Metodisti kirikus toimuvatest kontsertidest, kus on kavas A. Pärdi ja J. MacMillani teosed. 31. märtsil TÜ ajaloomuuseumis toimunud "Morgensterni muusikatunnist", kus L. Langsepp tutvustas ajaloolisi harfe. 30. märtsil etendus Nõmme kultuurikeskuses E. Künneke operett "Onupoeg Bataaviast"

  20. Logistikaärimeeste uues huviorbiidis on Vietnam / Jaana Pikalev

    Index Scriptorium Estoniae

    Pikalev, Jaana

    2010-01-01

    Eesti Logistikaklastri delegatsioon läheb visiidile Vietnami ja Hiinasse. Eesmärk on tutvuda Vietnami turu võimalustega ning luua suhteid Vietnami klientide ja arvamusliidritega. Hiinas külastatakse logistika- ja transpordimessi. Kavas on alla kirjutada koostöömemorandumid

  1. Kummardus Alberto Sordile

    Index Scriptorium Estoniae

    2005-01-01

    5.-7. maini on Tallinna Õpetajate Majas Roomat tutvustavate ürituste sarjas filmiprogramm "Tänan, Alberto!", mis tutvustab itaalia näitleja Alberto Sordi (1919-2003) loomingut. Filme tutvustab näitleja Alfiero Toppetti. Lisatud filmide kava

  2. Simmi "Head käed" tuli, nägi ja võitis / Triin Tael

    Index Scriptorium Estoniae

    Tael, Triin

    2002-01-01

    Berliini 52. filmifestivali "Panorama Special" kavas olnud Peeter Simmi Eesti-Läti ühisfilm "Head käed" saavutas hea publikuedu ning jagas sloveenlase Maja Weiss'i filmiga "Piirivalvur" Manfred Salzgeberi auhinda, mis on mõeldud subtiitrite tegemiseks filmi levitamisel euroopa ekraanidele. P. Simm on rahul ja plaanib uut filmi

  3. Karunahk ja Berlinale kroonijuveel / Lauri Kärk

    Index Scriptorium Estoniae

    Kärk, Lauri, 1954-

    2006-01-01

    56. Berliini filmifestivali filmide auhindamisest- Kuldkaru saanud Jasmila Zhbavici "Grbavica", režii Hõbekaru saajad britid Michael Winterbottom ja Mat Whitecross filmi eest "Teekond Guatanamosse" ("The Road to Guantanamo"). Autori lemmik oli aga Panorama kavas olnud Neil Jordani "Hommikusöök Pluutol". Lisatud nimekiri "56. Berlinale peaauhinnad"

  4. Britid tahavad investeerida Eestimaa tuulde ja biomassi / Agnes Ojala

    Index Scriptorium Estoniae

    Ojala, Agnes

    2009-01-01

    Suurbritannia rahvusvaheline ettevõte Oxford Sustainable Group on taastuvenergiaprojektide arendamiseks loonud investeerimisfondi Oxford Renewable Energy Fund 9. Seni on firma keskendunud Ida- ja Kesk-Euroopa riikidele. Eesti taastuvenergeetikaga tegelevate ettevõtete esindajad usuvad, et välisinvesteeringutele võiks siin ruumi olla. Diagramm: Taastuvenergia osakaal kasvab lähiajal kümnekordseks. Vt. samas: Bioetanoolitehas endiselt kavas

  5. Teated

    Index Scriptorium Estoniae

    2008-01-01

    Kontserdid TÜ aulas: Tartu Ülikooli kammerkoori kevadkontsert 16. märtsil, pianist Peep Lassmann 18. märtsil (kavas: Sumera "Pala aastast 1981", Liszt-Rossini "Stabat Mater", Liszt-Verdi "Rigoletto parafraas", Liszt "Tuisk" ja "Hispaania rapsoodia"), saksofonikvartett Sax-Est 19. märtsil, kontsert "Richard Ritsing - 105" 28. märtsil

  6. Poola ootab USA maaväelasi

    Index Scriptorium Estoniae

    2014-01-01

    Poola kaitseministri Tomasz Siemoniaki sõnul saadab USA Poolasse maavägesid, et laeindada NATO kohalolekut ajal, mil pingeline olukord Ukrainas kestab, kirjutas Washington Post. Siemoniak ütles lehele, et sõjalised planeerijad juba töötavad vastava kava üksikasjade kallal. Ta lisas, et tõenäoliselt saadetakse USA sõdureid ka Baltimaadesse

  7. Inimene tähistaeva all / Marju Riisikamp

    Index Scriptorium Estoniae

    Riisikamp, Marju, 1958-

    2011-01-01

    12. - 15. maini toimunud 5. Türi kevadfestivalist alapealkirjaga "Tähistaevas", festivali korraldaja Iren Lill. Festivali kavas olid raadio Ööülikooli salvestused, loengud, fotonäitus, animafilmi töötuba, tähetorni Orion, Mart Saare majamuuseumi külastus Hüpassaares, loodusmatkad, Urmas Sisaski autoriõhtu ja teised kontserdid

  8. Cabaret Voltaire ja "Kabaret das Lust" / Marko Raat

    Index Scriptorium Estoniae

    Raat, Marko, 1973-

    2000-01-01

    Prantsuse režissööri Catherine Breillatþ "Romanss" ja pornograafia mõiste ning Andres Maimiku, Arbo Tammiksaare, Juhan Ulfsaki Kabaret das Lust kava "Elu mõte" ja selle raames näidatud Tammiksaare-Maimiku mängufilmi sugemetega dokumentaalfilm "Macbeth" : loominguline ühendus "Suits"

  9. USA panustab keskkonda / Jeffrey Goldstein

    Index Scriptorium Estoniae

    Goldstein, Jeffrey

    2007-01-01

    USA uus energiapoliitika kava näeb ette bensiini tarbimise vähendamist järgneva 10 aasta jooksul 20%, mis omakorda vähendab ameeriklaste autodest eralduva süsihappegaasi heitmete kasvu ning vähendab sõltuvust naftast

  10. Посол США : мы поддерживаем Эстонию / Стэнли Дэвис Филлипс ; интерв. Эркки Баховски

    Index Scriptorium Estoniae

    Филлипс, Стэнли Дэвис

    2007-01-01

    USA suursaadik Eestis Stanley Davis Phillips vastab küsimustele, mis puudutavad USA positsiooni Tõnismäe pronkssõduri suhtes, Eesti saatkonna piiramist Moskvas, USA ja Venemaa suhteid ning koostööd, sõda terrorismiga, USA kava paigutada Tšehhi ja Poolasse raketitõrjebaasid, Eesti presidendi Toomas Hendrik Ilvese visiiti USAsse

  11. Festival "Maailmafilm" sobib hästi akadeemilise vaimuga linna / Kadri Rannamäe

    Index Scriptorium Estoniae

    Rannamäe, Kadri

    2008-01-01

    V festivali "Maailmafilm", mis algab 24. märtsil Eesti Rahva Muuseumi näitusemajas Tartus, tutvustavad muuseumi direktor Kristjan Raba ja festivali tegevjuht Taavi Tatsi. Esilinastub Liivo Niglase, Diane Perlovi ja Frode Storaasi "Kalarahvas". Kavas on ka eriprogrammid: kirjanikud filmis, klassiku Timothy Aschi filmid Amazonase indiaanlastest ja filmid inimesest linnas

  12. ELi 52 miljardist saab lõviosa keskkond / Hindrek Riikoja

    Index Scriptorium Estoniae

    Riikoja, Hindrek

    2006-01-01

    Ilmunud ka: Postimees : na russkom jazõke 13. veebr. lk. 3. Euroopa Liidu struktuurifondidest Eestile aastateks 2007-2013 eraldatavast 52 miljardist kroonist läheb esialgse kava kohaselt 13,4 miljardit krooni keskkonnale, 11 miljardit haridusküsimuste lahendamiseks ning 11,8 miljardit ettevõtluse ja teaduse arendamiseks. Diagramm: Euroraha saajad

  13. Kontserthuset Göteborg. Göteborgs Symfoniker, chefdirigent: Neeme Järvi. Dirigent: Neeme Järvi. Solist: Paata Burchuladze, bas. Kontsertmästare: Per Enoksson, Christer Thorvaldsson. Onsdag 12. mars 1997 Stora salen (brun serie)

    Index Scriptorium Estoniae

    1997-01-01

    Kontserdi kavas juttu: Eduard Tubin. Süit balletist "Kratt", Modest Mussorgski "Surma laulud ja tantsud" ja Jean Sibeliuse sümfoonia N 1, e-moll op. 39 Lk. 2-4: Kruckenberg, Sven: Tubin - Svit ur Kratt. Lk. 8 lühidalt Neeme Järvi edaspidisest tööst

  14. Mida vaadata pimedatel öödel? / Mati Sepping

    Index Scriptorium Estoniae

    Sepping, Mati

    2006-01-01

    Euroopa Filmiakadeemia liige tutvustab kuut filmi - Euroopa 2006.a. parima filmi nominenti, millest viis on ka 10. Pimedate Ööde Filmifestivali kavas : "Tee Guantanamosse", "Tuul, mis sasib odrapõldu", "Hommikusöök Pluutol", "Teiste elu", "Grbavica"

  15. Maailma suurim tool

    Index Scriptorium Estoniae

    2000-01-01

    AS Tartu näitused, Tartu Kunstikool ja ajakiri 'Diivan' korraldavad 9.-11. III Tartu messikeskuse I paviljonis näituse 'Tool 2000'. Eksponeeritakse 2000 tooli, mille hulgast valitakse TOP 12. Messikeskuse territooriumile on kavas püstitada maailma suurim tool. Samal ajal II paviljonis kaksikmess 'Sisustus 2000' ja 'Büroo 2000'.

  16. Suurepärane! Ma ostan selle! / Vanessa Friedman

    Index Scriptorium Estoniae

    Friedman, Vanessa

    2000-01-01

    Liibanoni päritolu, Pariisis elaval Mouna Ayoub'il, kes kulutab aastas kõrgmoele 16 miljonit krooni, on kavas avada oma muuseum. M. Ayoub ostab rõivaid Valentinolt, Diori, Givenchy ja Chaneli moemajadest, Gaultier' ja Versace kauplustest, kübaraid Philip Treacy'lt ja mujalt

  17. Riik pumpab uppunud laevast kütuse välja / Erik Rand

    Index Scriptorium Estoniae

    Rand, Erik

    2006-01-01

    Kuna tänavu märtsis Vaindloo saare lähedal põhja läinud kaubalaeva Runner 4 omanikfirma ei ole astunud reostuse likvideerimiseks mingisuguseid samme, hakkab kaubalaeva kütusepaakide tühjakspumpamisega tegelema Eesti riik, väljapumpamisega seotud kulud on kavas sisse nõuda laeva omanikult. Lisa: Runner 4 uppumine

  18. Jaapani anime vallutab kinosaale / Karilin Engelbrecht

    Index Scriptorium Estoniae

    Engelbrecht, Karilin

    2008-01-01

    Jaapani anime filmidest (seekord peamiselt Ghibli stuudio omad), mida saab näha 4.-13. aprillini Tallinnas Sõpruse kinos ja 5.-10. aprillini Tartus Athena keskuses II Jaapani animefilmide festivalil JAFF. Lisatud tänane kava Tallinnas ja Tartus ning "Väike sõnastik"

  19. Berliini festival asub uuenduste teele / Lauri Kärk

    Index Scriptorium Estoniae

    Kärk, Lauri, 1954-

    2002-01-01

    Berliini 52. filmifestival algab täna sakslase Tom Tykweri mängufilmiga "Taevas". Festivali uue direktori Dieter Kosslicki uuenduseks on saksa filmi endisest tunduvalt suurem osakaal. Esmakordselt on festivali "Panorama Special" kavas eesti mängufilm, milleks on Peeter Simmi "Head käed". Eesti filmid on esil ka festivali suurel filmiturul

  20. Berlinale poolel teel / Lauri Kärk

    Index Scriptorium Estoniae

    Kärk, Lauri, 1954-

    2002-01-01

    Berliini 52. filmifestivali käigust. Täna on festivali "Panorama Special" kavas Peeter Simmi "Head käed", mida publikule juba päris edukalt paar korda näidatud. Eesti filmid on esil ka festivali suurel filmiturul. Konkursi filmidest lähemalt prantslase F. Ozoni "8 naist" ("8 femmes")

  1. Eestlased kinometropolis / Olle Mirme

    Index Scriptorium Estoniae

    Mirme, Olle, 1973-

    2002-01-01

    Berliini 52. filmifestivali Panorama valikprogrammi kavas olnud Peeter Simmi Eesti-Läti ühisfilm "Head käed" saavutas hea publikuedu ning jagas Manfred Salzgeberi auhinda, mis on mõeldud subtiitrite tegemiseks filmi levitamisel euroopa ekraanidele. Žürii tõstis esile Toomas Raudami stsenaariumi originaalsust ja P. Simmi režiid. Pikemalt ka pressikonverentsist

  2. ETV noortekoor võitis Šveitsi koorifestivali peapreemia

    Index Scriptorium Estoniae

    2009-01-01

    ETV noortekoor Külli Kiiveti juhatusel pälvis 14.-19. aprillini Šveitsis toimunud 45. rahvusvahelisel koorifestivalil "Montreux Choral Festival 2009" nii žürii peapreemia kui ka parima kava ja interpretatsiooni ning kohustusliku laulu preemia

  3. Kultusfilmide festival kompab Ameerika filmide identiteeti / Ilmar Raag

    Index Scriptorium Estoniae

    Raag, Ilmar, 1968-

    2006-01-01

    27. jaanuarist 3. veebruarini on Sõpruse ekraanil järjekordne Manifesti filminädal, seekord USA filmiajaloo eredamatest teostest. Lähemalt filmidest, eelkõige Robert Aldrich'i film noir'ist "Kiss Me Deadly" (1955). Lisatud filminädala kava

  4. Muusikamaailm : Luzerni festivali tipphetked. Pärdi ja Singi teosed Kokkolas. Josef Tal 90. Praemium Imperiale Henzele. Alan Hovhaness surnud / Priit Kuusk

    Index Scriptorium Estoniae

    Kuusk, Priit, 1938-

    2000-01-01

    Luzerni muusikafestivalist Šveitsis. Kesk-Põhjamaa Kammerorkestri uue hooaja kavas oli ka Singi ja Pärdi teoseid. Lühidalt J. Tali tegevusest. H.W. Henze pälvis jaapani muusikapreemia Praemium Imperiale. Lühidalt A. Hovhanessi tegevusest

  5. Nõukogu kinnitas Türi kolledži õppetöö kolimise Tartusse

    Index Scriptorium Estoniae

    2010-01-01

    Novembrikuu istungil otsustas TÜ nõukogu Türi kolledžis oleva keskkonnakorralduse ja planeerimise õppekava liita Tartus loodus- ja tehnoloogiateaduskonna (LOTE) juurde. TÜ peahoone ees protestisid selle kava vastu kolledži üliõpilased

  6. "Translocal Express" tembutab jälle / Rael Artel, Airi Triisberg

    Index Scriptorium Estoniae

    Artel, Rael, 1980-

    2008-01-01

    Korraldajad 22. ja 23. II Okupatsioonide Muuseumis toimuvast rahvusvahelisest seminarist "Translocal Express. Jubilee Edition", kus vaatluse all on kaasaegse kunsti ja natsionalismi suhted. Seminari kava. Eesti kunstnikest esineb Flo Kasearu, esitletakse Rael Arteli ja Airi Triisbergi raamatut "Public Preparation - Biennale of Young Artists"

  7. Kriitikast / Leelo Kõlar

    Index Scriptorium Estoniae

    Kõlar, Leelo, 1927-

    1999-01-01

    Vestlus Rein Rannapiga pärast sooloesinemist 29.11.1976 Estonia kontserdisaalis. - Rein Metsa esinemisest kontserdil 02.12.1976 Estonia kontserdisaalis, kavas Bartoki 1. klaverikontsert. - Kalle Randalu klaveriõhtust. - Eesti pianistide esinemistest. - Vestlus Kalle Randaluga. - Roger Woodward esinemisest Estonia kontserdisaalis 1994. a. juunis

  8. 1600 last õppis linnaökoloogiat / Askur Alas

    Index Scriptorium Estoniae

    Alas, Askur, 1973-

    2003-01-01

    27.01 lõppenud Tallinna Elukeskkonna projektis osales vabatahtlikult rohkem kui 1600 koolilast. Tallinna elukeskkonna probleemidele pühendatud projekt algas juba novembris, säästlikku mõtteviisi ja loodushoidlikku eluviisi propageerivaid üritusi on kavas ka edaspidi

  9. Öö täis õuduseid / Signe Sillasoo

    Index Scriptorium Estoniae

    Sillasoo, Signe

    2009-01-01

    PÖFFi ja Tudengipäevade öiste filmiseansside sarja esimesest filmiööst Night Of the Movie Eaters 21. aprillil kinos Sõprus, mil kavas kolm õudusfilmi : Mark ja Jay Duplass' "Kottpea" (USA, 2008), Patrik Syverseni "Inimjaht" (Norra, 2008), Yoshihiro Nishimura "Tokyo Gore Police" (Jaapan, 2008)

  10. Passa Porta kirjandusfestival ja Euroopa põhiseadus värssides / Jüri Talvet

    Index Scriptorium Estoniae

    Talvet, Jüri, 1945-

    2009-01-01

    27. märtsil esitasid kirjanikud Brüsseli kirjandusmaja Passa Porta festivalil 54 kirjaniku osalusel valminud Euroopa "värsspõhiseaduse". "Värsspõhiseaduse" idee andis belgia kirjanik David Van Reybrouck, kes koos kirjaniku ja poliitikateadlase Peter Vermeerschiga pani kokku "värsspõhiseaduse" kava, mille "raami" kirjutasid valmis Geert Van Istendael, Xavier Queipo, Manza ja Laurence Vielle

  11. Kohalik väikefirma Programeter üritab Räniorus läbi murda / Raigo Neudorf

    Index Scriptorium Estoniae

    Neudorf, Raigo

    2008-01-01

    Mark Kofmani ja Anton Litvinenko poolt asutatud OÜ Programeter töötas välja tarkvara, millega saab mõõta ja analüüsida tarkvaraprogrammeerijate tööd ja oskusi. Väikefirmal on kavas avada oma kontor USAs Silicon Valley's. Vt. ka: Meeskond kõigepealt; Rahas ei suple

  12. Ekspert : klaas Vabadussamba valmistamiseks eriti hästi ei kõlba / Mari Kodres

    Index Scriptorium Estoniae

    Kodres, Mari

    2008-01-01

    Tallinnasse Harjumäele ja Islandi väljakule kavandatavate mälestusmärkide klaaslahendusest. Islandi väljakule on kavas avada vastupanu mälestusmärk "Murtud müür", autorid Kuulo Vahter, Ivo Lill ja Ain Rööpson. Kommenteerivad Meeli Kõiva ja klaasiinsener Aulis Bertin Soomest

  13. Sõprus näitab filmi maailma lastest

    Index Scriptorium Estoniae

    2006-01-01

    UNICEFi palvel valmistasid kaheksa tuntud režissööri kassett-filmi maailma kannatavatest lastest "Kõik nähtamatud lapsed" ("All the Invisible Children") : Prantsusmaa - Itaalia 2005. Film linastus PÖFFil ja on Sõpruse kino kavas

  14. Parteide salajased rahastajad tuleb välja anda / Raimo Poom, Mirko Ojakivi ; kommenteerinud Ülle Madise, Kristen Michal, Priit Toobal

    Index Scriptorium Estoniae

    Poom, Raimo

    2009-01-01

    Uue erakonnaseaduse eelnõus plaanitakse muuta ka erakondade rahastamise põhimõtteid, seaduse muutmise kava salastamisest. Hiljemalt 31. oktoobril peab justiitsministeerium saatma vastuse Euroopa Nõukogu korruptsioonivastaste riikide ühendusele GRECO, kelle raportis nõuti Eestilt sõltumatut erakondade rahastamist kontrolliva organi sisseseadmist. Näiteid erakondade küsitava rahastamise kohta

  15. Veneetsia festivali avab Spielberg / Tiit Tuumalu

    Index Scriptorium Estoniae

    Tuumalu, Tiit, 1971-

    2004-01-01

    Eelseisvast Veneetsia 61. filmifestivalist. Kavas on ka Iisraeli "Tõotatud maa", mille episoodi Arvo Pärdi "Peace upon You, Jerusalem" esitusega ETV tütarlastekoori poolt käis režissöör Amos Gitai filmimas Eestis

  16. Paja-katla mäng finaali eel / Deivil Tserp

    Index Scriptorium Estoniae

    Tserp, Deivil, 1968-

    2005-01-01

    Autor kritiseerib Eesti suuremate erakondade juhtide valimiseelset debatti 12. oktoobril Eesti Televisiooni eetris olnud "Valimisstuudio" saates, kus poliitikud püüdsid paljastada üksteise tumedaid tegusid selle asemel, et selgitada valijatele, mida nende erakondadel on kavas tulevikus teha eestimaalaste hüvanguks

  17. "Sokrovishtsha mirovogo iskusstva v Tallinne" / Nelli Kuznetsova

    Index Scriptorium Estoniae

    Kuznetsova, Nelli

    2005-01-01

    Boris Pilar organiseerib vene kunsti näitusi Tallinnas. 1. mail 2006 on kavas avada Tallinna Õpetajate Majas ikoonide ja tuntud vene maalikunstnike tööde näitus Pihkva muuseumi kogudest ja 2007. aastal näitab oma kunstivarasid Tallinnas Jaroslavli kunstimuuseum

  18. Avatud meeled ja intellektuaalsed mõttemängud / Gerhard Lock ja Evelin Lagle

    Index Scriptorium Estoniae

    Lock, Gerhard, 1978-

    2010-01-01

    10. sünnipäeva tähistava Küberstuudio tegevusest. 2. märtsil Kumu auditooriumis etendunud Monika Mattieseni ja Hasso Krulli multimeediaooperist "Loomise mõnu", kavas olid ka Mirjam Tally ja Erkki-Sven Tüüri elektroakustilised teosed flöödile ja kammerorkestrile

  19. Täna toimub Kadrioru lossis väliskunsti muuseumis...

    Index Scriptorium Estoniae

    2004-01-01

    Näituse "Kunstnik ja tema kodu. C. T. von Neffi kunstikogu Piira ja Muuga mõisast" raames toimuva ettekannete päeva "19. sajandi keskpaiga kunstiruum" kava. Esinevad Jevgenia Kiritshenko, Juri Gudõmenko, Ants Hein, Kadi Polli, Veronika Bogdan, Ingrida Raudsepa, Tiina Abel

  20. 30. III tutvustab Mooste külalisstuudio Tallinna Kunstihoone galeriis...

    Index Scriptorium Estoniae

    2005-01-01

    Tutvustatakse resideerimisprogrammi võimalusi ning keskkonnakunsti sümpoosioni "PostsovkhoZ". Ürituse kava (John Grzinichi lühifilm MoKSist", Dirk Lange näituse "ööTöö" avamine, ajakirja Palaster esitlus, Marcus Öhrnilt oma projekti, video ja performance'i tutvustus, Kurt Korthalsi, John Grzinichi kontsert jne.)

  1. Kes on järgmine? / Feliks Mägus

    Index Scriptorium Estoniae

    Mägus, Feliks, 1960-

    2008-01-01

    Nordic Hotels OÜ juhatuse esimees taunib valitsuse kava tõsta majutusteenuste käibemaksu praeguselt 5 protsendilt 18 protsendini ning ta kirjeldab, mida tõi majutuse käibemaksu tõstmine kaasa Iirimaal 1980-ndatel aastatel

  2. "Väliseestlus - väljasuremisele määratud?" / Merike Pärtel

    Index Scriptorium Estoniae

    Pärtel, Merike

    2007-01-01

    kevadiste New Yorgi Eesti Kultuuripäevade (29. märts - 1. aprill) ajal toimuv foorum kutsub kõiki arutlema eestluse oleviku ja tuleviku üle. Kava ja alateemad, info: merikepartel@yahoo.com või telefon 646 750 6872

  3. Kontserthuset Göteborg. Lördag 15. mars 1997 Stora salen

    Index Scriptorium Estoniae

    1997-01-01

    Kontserdi kavas juttu: Eduard Tubina "Balalaikakontsert" ning Wilhelm Stenhammari ja Sergei Prokofjevi teosed Lk. 3-4: Kruckenberg, Sven: Tubin - Balalajkakontsert. Kontserthuset Göteborg. Göteborgs Symfoniker, chefdirigent: Neeme Järvi. Dirigent: Neeme Järvi, solist: Gennady Zut, balalajka. Kontsertmästare: Per Enoksson, Christer Thorvaldsson. Lördag 15. mars 1997 Stora salen (grön serie)

  4. Meedialabor Tallinnas / Sirje Helme

    Index Scriptorium Estoniae

    Helme, Sirje, 1949-

    2001-01-01

    KKEK aastanäitus "Interstanding 4" alapealkirjaga "end repeat" Rotermanni soolalaos. "Interstanding" on valminud koostöös EKA-ga Ando Keskküla initsiatiivil. "Interstanding 4" programmi "end repeat" autor Mare Tralla. Medialabist. Konverentsi kava lk. 21.

  5. Film, mis sobib tARTuFFile nagu rusikas silma / Tiit Tuumalu

    Index Scriptorium Estoniae

    Tuumalu, Tiit, 1971-

    2009-01-01

    Tartu armastusfilmide festivali tARTuff filme - Venemaa 2009. a. melodraama "Tuvike - viimane suvi N Liidus" ("Golibka"), režissöör Sergei Oldenburg-Svintsov, peaosalise prototüübiks Kaasani kunstnik Gennadi Arhirejev. Lisatud festivali filmide kava

  6. В Тарту покажут фильмы о любви / Tийт Туумалу

    Index Scriptorium Estoniae

    Туумалу, Тийт

    2009-01-01

    Tartu armastusfilmide festivali tARTuff filme - Venemaa 2009.a. melodraama "Tuvike - viimane suvi N Liidus" ("Golibka"), režissöör Sergei Oldenburg-Svintsov, peaosalise prototüübiks Kaasani kunstnik Gennadi Arhirejev. Lisatud festivali filmide kava

  7. Kinos voolab naftat / Tiit Tuumalu

    Index Scriptorium Estoniae

    Tuumalu, Tiit, 1971-

    2010-01-01

    Filmistuudio Nafta lühifilmide kava 1. oktoobrist 2010 Tallinna kinos Artis. Kavasse kuuluvad uued linateosed: Heleri Saariku "Näkilugu" ja Margus Paju "Blackout" ning Priit Pääsukese "Must Peeter" (2008), Peeter Sauteri novelli "Must notsu" ekraniseering

  8. "Musta Peetri" stuudio Nafta näitab uusi lühifilme / Andres Laasik

    Index Scriptorium Estoniae

    Laasik, Andres, 1960-2016

    2010-01-01

    Filmistuudio Nafta lühifilmide kava 1. oktoobrist 2010 Tallinna kinos Artis. Kavasse kuuluvad uued linateosed Heleri Saariku "Näkilugu" ja Margus Paju "Blackout" ning Priit Pääsukese "Must Peeter" (2008), Peeter Sauteri novelli "Must notsu" ekraniseering

  9. Tõusev Hiina / Abdul Turay

    Index Scriptorium Estoniae

    Turay, Abdul, 1967-

    2011-01-01

    Hiina on suur riik suure majandusega ja eestlasedki võiksid sealsele turule minna, kuid Eestis on Idamaad äraunustatud ja Hiinat tundma õppida on raske. Mais teatasid hiinlased, et neil on kavas avada eestikeelne telekanal. Hiina ühiskonna eripäradest. Hiinlaste ja eestlaste sarnasustest ning erinevustest

  10. Kohus keelas Kõusaare Cannes'i pääsenud filmi näitamise Eestis / Kaarel Kressa

    Index Scriptorium Estoniae

    Kressa, Kaarel, 1983-

    2007-01-01

    Cannes'i filmifestivali kavas "Un certain regard" on tänavu ka Kadri Kõusaare mängufilm "Magnus" : produtsent Donald Fernandes : Eesti (Vitamin K Film) - Suurbritannia (Donus Films Limited). Filmi levitamisõigusega seotud kohtumäärusest

  11. Mängufilm "Magnus" sai kohtus kuulsaks ja Eestis keelatuks / Risto Berendson

    Index Scriptorium Estoniae

    Berendson, Risto, 1975-

    2007-01-01

    Cannes'i filmifestivali kavas "Un certain regard" on tänavu ka Kadri Kõusaare mängufilm "Magnus" : produtsent Donald Fernandes : Eesti (Vitamin K Film) - Suurbritannia (Donus Films Limited). Filmi levitamisõigusega seotud kohtumäärusest

  12. "Berlinale" pakub sõltumatuid / Endel Link

    Index Scriptorium Estoniae

    Link, Endel

    2004-01-01

    Berliini filmifestivalist, mis algas 5. veebruaril Anthony Minghella mängufilmiga "Külmale mäele" ("Cold Mountain) : Ameerika Ühendriigid. Festivali kavas olevatest filmidest. Žüriid juhib USA näitleja Frances McDormand

  13. Suvemuusika : Oramo ja Kaljuste / Igor Garshnek

    Index Scriptorium Estoniae

    Garšnek, Igor, 1958-

    1999-01-01

    25. augustil Estonia kontserdisaalis toimunud Birmingami SO kontserdist. Kavas G. Benjamini "Sudden Times", Sibeliuse Viiulikontsert ja Brahmsi 2. sümfoonia. 26. augustil Tallinnas endise tselluloosivabriku katlamajas toimunud kontserdist ja videosalvestusest, kus kanti ette Mozarti "Reekviem" Kosovos hukkunute mälestuseks

  14. Rohkem tolerantsi / Lauri Kärk

    Index Scriptorium Estoniae

    Kärk, Lauri, 1954-

    2003-01-01

    Berliini 53. filmifestival avati USA muusikaliga "Chicago", mis valmis Rob Marshalli käe all John Kanderi, Fred Ebbi ja Bob Fosse muusikali järgi. Festivali juht Dieter Kosslick rõhutab loosungit "Towards Tolerance", mis olevatki festivali kava alusmõtteks

  15. VI Tallinna Arhitektuuritriennaal "Feeling Architecture"

    Index Scriptorium Estoniae

    2005-01-01

    15.-17 IX 2005 Niguliste muuseum-kontserdisaalis toimuva triennaali kava. Esinevad Peter Davey, Michael Hensel (Inglismaa), Peter Zumthor (Šveits), Juhan Maiste, Vilen Künnapu (Eesti), Ivan Kroupa (Tšehhi), Juha Leviskä (Soome), Gennadi Revzin (Venemaa), Lars Spuybroek (Inglismaa-Holland)

  16. Barn music at St Donat's castle / Philip Gross

    Index Scriptorium Estoniae

    Gross, Philip, 1952-

    2011-01-01

    Muusikafestivalist "Vale of Glamorgan", mis oli 2010. a. pühendatud Arvo Pärdile. Eesti kammermuusikaansambli Resonabilis kavas oli ka festivali tellimusel valminud uelsi helilooja Gareth Peredur Churchilli "Vocable", mille teksti kirjutas Philip Gross. Festivalikontsertide muljeid leiab Grossi luuletsüklis "Barn music" (avaldatud samas ajakirjanumbris, lk. 42-43)

  17. ATP alane konverents Tartus / Tõnis Tamm

    Index Scriptorium Estoniae

    Tamm, Tõnis

    2004-01-01

    17.-19. maini 2004 toimus Eurosert OÜ korraldusel Tartus IIR-i (International Institute of Refrigeration) konverents, mille lõpparuandena koostati ettepanekute kava ÜRO Euroopa majanduskomisjonile WP11 kontrolli parandamiseks kiiresti riknevate toiduainete veoks ja sellel veol kasutatavate erivahendite üle

  18. Eesti videokunsti otsingutel / Raivo Kelomees

    Index Scriptorium Estoniae

    Kelomees, Raivo, 1960-

    2006-01-01

    XII Pärnu rahvusvaheline video- ja filmifestival "Klassiahastus" Pärnu mudaravilas 18. ja 19. XI. Peapreemia sai Kristina Normanni video "Pribaldid", ära märgiti Moira Tierney video "Yoyoyogasmana". Inglismaal Brightonis 1.-3. XII toimuva festivali kava

  19. Geeniuste tagasitulek : Louis Kahni päevad Kuressaares / Toivo Tammik

    Index Scriptorium Estoniae

    Tammik, Toivo

    2006-01-01

    6. X avatakse Louis Kahni portree Kuressaare raekojas ja näitus Kuressaare linnuses, Kuressaare Linnateatris linastub arhitekti poja Nathaniel Kahni film "My architect. Son's journey" (2003). 7. X toimuva rahvusvahelise arhitektuurikonverentsi kava. 1956. a. Philadelphias kohtunud Saaremaal sündinud Louis Isadore Kahnist ja Järvamaal sündinud August Eduard Komendandist

  20. Derek, Sally ja Tilda Swinton / Kalmer Saar

    Index Scriptorium Estoniae

    Saar, Kalmer

    2004-01-01

    Briti Nõukogu toetusel toimuvad Pärnus, Tartus ja Tallinnas PÖFFi suvekino organiseerimisel inglise filmide päevad "Geeniuste mäss", kus näidatakse seitset inglise väärtfilmi. Lähemalt Derek Jarmani filmist "Edward II" (1991) ja Sally Potteri Virginia Woolfi ekraniseeringust "Orlando" (1992). Lisatud filmipäevade kava

  1. Riik ostab saastekvoodi eest sadu elektriautosid / Raigo Neudorf

    Index Scriptorium Estoniae

    Neudorf, Raigo

    2011-01-01

    Valitsus kiitis heaks 10 miljoni saastekvoodi ühiku ehk AAU müügi Jaapani konglomeraadile Mitshubishi Corporation, vastutasuks saadava raha eest rahastab riik kolmest osast koosnevat kava, mis näeb ette laadimisvõrgustiku rajamise elektriautode tarbeks, elektriautode soetamiseks mõeldud toetusi ja enam kui 500 elekriauto ostmist riigi poolt

  2. 2008. aastal tuleb SEPA. Mida see tähendab?

    Index Scriptorium Estoniae

    2006-01-01

    Ilmunud ka: Finansovõi Menedzhment : infovõpusk nr. 9 nov. lk. 8-10. Alates 2008. aastast peaks Euroopa Komisjoni kava kohaselt alustama toimimist Euroopa Liidu ühtne makseala SEPA (Single Euro Payments Area), mis aitab kaasa pangateenuste hinna ühtlustumisele liikmesriikides. Lisad. Tabelid: SEPA-propaganda; SEPA asjatundjad Eestis

  3. Põrgulikud piinad ja tingimusteta armastus / Margit Tõnson

    Index Scriptorium Estoniae

    Tõnson, Margit, 1978-

    2004-01-01

    Helsingis 17. korda toimuva festivali "Armastus ja Anarhia" kavas olnud filme - Takashi Miike "Üks vastamata kõne" ("One Missed Call"), korealase Park Chan-Wooki "Vana poiss" ("Old Boy") ja Jean-Luc Godardi "Meie muusika" ("Notre Musique")

  4. NYYD Ensemble

    Index Scriptorium Estoniae

    2002-01-01

    NYYD Ensemble'i duost Traksmann - Lukk E.-S. Tüüri teosega "Symbiosis", mis on salvestatud ka hiljuti ilmunud NYYD Ensemble'i CDle. 2. märtsil Rakvere Teatri väikeses saalis ja 3. märtsil Rotermanni Soolalaos, kavas Tüür, Kaumann, Berio, Reich, Yun, Hauta-aho, Buckinx

  5. Raoul Kurvitz soovitab: Stalkeri monumendi etendused

    Index Scriptorium Estoniae

    2011-01-01

    Rotermanni kvartalisse kohta, kus filmiti Andrei Tarkovski "Stalker", on kavas rajada Stalkerile pühendatud monument, mille autor on Raoul Kurvitz. Monumendi rajamise idee pärineb projekti kaasautorilt Tarvo Hanno Varreselt. 10., 11., 17., 18., 23. ja 24. septembril toimuvad monumenti tutvustavad performance'id

  6. Uute tantsijate tulek / Heili Einasto

    Index Scriptorium Estoniae

    Einasto, Heili

    2017-01-01

    Tallinna Balletikooli galast Estonia teatris. Kavas olid katkendid balletiklassikast ning Marina Kesleri uuslavastus "Tütarlaps ja surm" Franz Schuberti muusikale. Tänavu said lisaks klassikalise balleti suuna lõpetajatele diplomi ka kaasaegse tantsu suuna läbinud noored. Vestlusest Tallinna Ülikooli balletiõppejõu Irina Pähniga

  7. Lasteaiad jäägu lastele / Hanno Pevkur

    Index Scriptorium Estoniae

    Pevkur, Hanno, 1977-

    2006-01-01

    Tallinna volikogu liige selgitab, miks temas tekitab küsitavusi linnavalitsuse kava rajada Tallinnasse 100 uut mänguväljakut. Autor leiab, et mänguväljakud saab rajada kavandatust neli korda odavamalt ning nad peaksid jääma ainult lasteaedade laste kasutada

  8. 21 ideed, millest võiks saada monument või skulptuur / Jüri Saar

    Index Scriptorium Estoniae

    Saar, Jüri, 1973-

    2008-01-01

    Tartu linnavalitsus kogus kokku 21 skulptuuride, monumentide ja mälestustahvlite ideed, et esile tõsta auväärseid kaaslinlasi ning ehitisi. Valmis dokument "Tartu linna monumentide ja skulptuuride rajamise kava aastateks 2008-2013". Kommenteerivad Tiit Kaunissaare ja Jüri Sasi

  9. Kunstnike moraalsed valikud kultuurikonfliktides = The moral choices of artists in cultural conflicts

    Index Scriptorium Estoniae

    2006-01-01

    Kaasaegse Kunsti Eesti Keskuse 4. ettekannete päev "Kunstnike moraalsed valikud kultuurikonfliktides" sarjast "Lisandusi eesti kunstiloole" Tallinna Kunstihoones 27.04.2006. Kava, esinevad Margit Sutrop, Johannes Saar, Andres Tali, Marek Järvik, Ene-Liis Semper ja Eero Epner, Marco Laimre. Soome filmirežissööri Pirjo Honkasalo dokumentaalfilmi "Melanhoolia kolm tuba" presentatsioon

  10. Psychoactive natural products: overview of recent developments

    Directory of Open Access Journals (Sweden)

    István Ujváry

    2014-03-01

    Full Text Available Natural psychoactive substances have fascinated the curious mind of shamans, artists, scholars and laymen since antiquity. During the twentieth century, the chemical composition of the most important psychoactive drugs, that is opium, cannabis, coca and "magic mushrooms", has been fully elucidated. The mode of action of the principal ingredients has also been deciphered at the molecular level. In the past two decades, the use of herbal drugs, such as kava, kratom and Salvia divinorum, began to spread beyond their traditional geographical and cultural boundaries. The aim of the present paper is to briefly summarize recent findings on the psychopharmacology of the most prominent psychoactive natural products. Current knowledge on a few lesser-known drugs, including bufotenine, glaucine, kava, betel, pituri, lettuce opium and kanna is also reviewed. In addition, selected cases of alleged natural (or semi-natural products are also mentioned.

  11. Eliisabeti kirikus kõlavad kooriteosed

    Index Scriptorium Estoniae

    2008-01-01

    Ülo Kriguli "Preces ad lucem" ("Palve valguse poole") ja Galina Grigorjeva "Nature morte" esiettekandest Eesti Filharmoonia Kammerkoori (dirigent Daniel Reuss) esituses 23. okt. Tallinnas Niguliste kirikus ja 24. okt. Pärnu Eliisabeti kirikus. Pärnu kontserdil kavas ka Cyrillus Kreegi "Taaveti" laulud ja Frank Martini "Missa". Pärnust sõidab koor Riiga professionaalsele kooride festivalile "Tenso päevad"

  12. Complementary and alternative interventions in asthma, allergy, and immunology.

    Science.gov (United States)

    Bielory, Leonard

    2004-08-01

    To review which herbs are most commonly used as complementary and alternative medicine (CAM) for treatment of asthma, allergy, and immunologic conditions. A review of the literature was performed using the PubMed and OVID databases searching the keywords asthma, allergy, and CAM to identify studies published between 1980 and 2003 that focused on Echinacea (Echinacea augustifolia, Echinacea pallida, and Echinacea purpurea); garlic (Allium); angelica; chamomile; ephedra; gingko; grape seed extract; licorice root (Glycyrrhiza); St. John's wort (Hypericum); kava kava (Piper); peppermint oil and leaf (Mentha); stinging nettle (Urtica); and ginseng (Panax) published in the English and German literature. Studies included in vitro and in vivo clinical trials and case reports selected according to the expert opinion of the author. Echinacea is one of the most common herbs used to treat symptoms of the "common cold" or upper respiratory tract allergies. Although no common drug interactions have been reported, there is a risk of hepatotoxicity, exacerbation of allergies and asthma, and anaphylactic reactions. Garlic is primarily used for cardiovascular health and relief of cough, colds, and rhinitis. Adverse effects commonly include gastrointestinal disturbances, change in body odor through the sweat and breath, and rarely allergic reactions or hypoglycemia. Other CAM agents, including angelica, German chamomile flower, ephedra, gingko, grape seed extract, licorice root, St. John's wort, kava kava rhizome, peppermint, stinging nettle, and ginseng, are also associated with significant adverse effects. The specialty of allergy and immunology has seen the second largest increase in the popularity of CAM (second only to practitioners who treat lower back pain). Almost all of the CAM interventions have displayed adverse effects, usually in the form of a hypersensitivity reaction. Allergists and clinical immunologists need to become more knowledgeable about CAM so that they can

  13. Urmo Rausi edu Pariisis / Anne Lõugas

    Index Scriptorium Estoniae

    Lõugas, Anne, 1951-

    1998-01-01

    1997. a. omandas Pariisis elava U. Rausi graafikat Prantsuse Rahvusraamatukogu. Ülevaates 'Estampe contemporaine ̉ la Bibliothéque Nationale de France' on 2656 teose seas esile tõstetud ka Edda Renoufi õpilase U. Rausi graafikat. Wernher Bouwensi välja antud ajakiri 'Nomaadid' esitleb U. Rausi litograafiaid eksperimentaalse graafikana. U. Rausi graafikatehnikast, kavas olevatest näitustest. U. Rausi kolm tööd omandas Tallinna kunstimuuseum.

  14. Saksa luure ja Liechtensteini varifirma : side Eestiga / Sulev Vedler

    Index Scriptorium Estoniae

    Vedler, Sulev, 1970-

    2008-01-01

    1999. aastal Saksa luureasutuse Bundesnachrichtendienst koostatud ettekandes Itaalia ärimehe Ernesto Preatoni kohta märgiti muu hulgas, et Preatoni hankis pangalitsentsi pistise abiga. Autori sõnul pidas Eesti Ekspress seda väidet tookord naeruväärseks, muu hulgas kukkus läbi Preatoni kava müüa 49% asutatava panga aktsiatest teistele välisinvestoritele, keda esindas Liechtensteini pealinnas registreeritud firma

  15. ETV kutsub tantsule / Tiit Tuumalu

    Index Scriptorium Estoniae

    Tuumalu, Tiit, 1971-

    2003-01-01

    Tantsufilmide õhtu "Meeste mängud" ETVs. Lähemalt filmidest "The Car Man" (koreograaf Matthew Bourne, režissöör Ross MacGibbon), "Achilleuse tulek" ("Enter Achilleus" : koreograaf Lloyd Newson, režissöör Clara van Gool), "Ühevärvilised inimesed, elutud unistused" ("Dead Dreams of Monochrome Men" : koreograaf Lloyd Newson, režissöör David Hinton). Lisatud filmide kava

  16. Toidukriisis maailm süüdistab biokütuste tootjaid / Sirje Rank

    Index Scriptorium Estoniae

    Rank, Sirje, 1966-

    2008-01-01

    Toiduainete järsu hinnatõusu tõttu on biokütused kasvava kriitika all. Tule all on ka EL-i kava kehtestada liikmesriikidele kohustus, et aastaks 2020 moodustaksid biokütused mootorikütustes vähemalt 10%. Vt. samas: Euroopa Liidus toetus vaid aastani 2009; Lootused teise põlve tehnoloogia peal. Diagramm: Raps, mais ja soja maailmaturul

  17. Birgitta festivali elav tuli

    Index Scriptorium Estoniae

    2007-01-01

    Birgitta festivalil Pirita kloostri müüride vahel 10.-19. aug. mängukavas: Moskva ooperiteatri Novaya Opera trupp esitamas ooperit, Maria Callase gala, klassikalist ja dzhässballetti, Vene Keiserlik Ballett kava "Tshaikovski in Swing", Anton Rubinshteini ooper "Deemon" (lavastaja Mihhail Jefremov), Arthur Honeggeri oratoorium "Jeanne d'Arc tuleriidal" (lavastaja Üllar Saaremäe, peaosas Mirtel Pohla)

  18. Eesti Energia: valitsus võtab aja maha ja laseb börsimõttel veel settida / Raimo Poom

    Index Scriptorium Estoniae

    Poom, Raimo

    2010-01-01

    Täna valitsuskabinetis toimuv arutelu ei paista keskenduvat mitte sellele, kas Eesti Energia börsile viimise plaan on hea või halb, vaid pigem sellele, kui kiire Eesti Energial oma plaanide rahastamisega on ning kas kõik ettevõtte soovid lähevad riigi eesmärkidega kokku. Eesti Energia investeeringute kava tekitab praegu rohkem küsimusi kui rahastamine

  19. Uudised : Urmas Alenderile pühendatud festival Paides. Heiki Mätlik kirjutab Bachist. Ungari muusika Balti misjonikeskuses. Hans van Manen lavastas Pärti

    Index Scriptorium Estoniae

    2000-01-01

    25. nov. Paides toimuvast U. Alenderi loomingule pühendatud muusikafestival-konkursist Alenderfest "Südame hääl". Ilmus H. Mätliku kolmeosaline traktaat Bachi lautomuusika interpretatsioonist ja arranzheerimisest kitarrile. 20. okt. Balti misjonikeskuses toimuvast ungari pärimusmuusikakontserdist. H. van Manen kasutab uue lühiballettide kava "Tantsu laureaadid" lavastuses A. Pärdi teost "Spiegel im Spiegel"

  20. USA suursaadik : toetame Eestit / Stanley Davis Phillips ; interv. Erkki Bahovski

    Index Scriptorium Estoniae

    Phillips, Stanley Davis

    2007-01-01

    USA suursaadik Eestis Stanley Davis Phillips vastab küsimustele, mis puudutavad USA positsiooni Tõnismäe pronkssõduri suhtes, Eesti saatkonna piiramist Moskvas, USA ja Venemaa suhteid ning koostööd, sõda terrorismiga, USA kava paigutada Tšehhi ja Poolasse raketitõrjebaasid, Eesti presidendi Toomas Hendrik Ilvese visiiti USAsse. Lisa: Stanley Davis Phillips. Ilmunud ka: Postimees : na russkom jazõke 16. mai lk. 5

  1. "Head käed" tõid Berlinalelt auhinna / Tiit Tuumalu

    Index Scriptorium Estoniae

    Tuumalu, Tiit, 1971-

    2002-01-01

    Berliini 52. filmifestivali tulemustest. Festivali "Panorama Special" kavas olnud Peeter Simmi "Head käed" saavutas hea publikuedu ning jagas sloveenlase Maja Weiss'i filmiga "Piirivalvur" Manfred Salzgeberi auhinda, mis on mõeldud subtiitrite tegemiseks filmi levitamisel euroopa ekraanidele. Kuldkaru jagasid briti Paul Greengrassi "Verine pühapäev" ja jaapanlase Hayao Miyazaki animafilm "Vaimudest viidud". Parima režissööri Hõbekaru sai Otar Ioseliani

  2. Haapsalu 725 : Haapsalu genius loci / Aidi Vallik

    Index Scriptorium Estoniae

    Vallik, Aidi, 1971-

    2004-01-01

    Pidustuste kavas (18.-20. VI, 7.-11. VII, 29. VII-1. VIII) on ka süvakultuuri: 20. VI dirigeerib Eesti-Soome sümfooniaorkestrit Anu Tali, Linnagaleriis juuni lõpuni Jaan Toomiku uute maalide väljapanek, Evald Okase muuseumis augusti lõpuni E. Okase tööde näitus, 27. VI-4. VII klaasipuhumise workshop

  3. Aitab hädaldamisest / Robert Antropov

    Index Scriptorium Estoniae

    Antropov, Robert, 1965-

    2006-01-01

    Endine politseijuht on seisukohal, et politseinike ja päästjate nappuses ei saa süüdistada ainult väikseid palku, küsimus on valikutes: kuidas ja millesse ressursse paigutada. Kalle Laanet ja Raivo Aeg vastavad küsimusele, mis on nende haldusalas konkreetselt kavas, et politsei saaks täita oma tegevusprioriteeti 100% ja tagada sisejulgeoleku. Vt. ka Robert Antropovi kommentaari 7. aug. Eesti Päevaleht lk. 2

  4. Berlinale Kuldkaru jagunes kahe filmi vahel / Andres Laasik

    Index Scriptorium Estoniae

    Laasik, Andres, 1960-2016

    2002-01-01

    Berliini 52. filmifestivali tulemustest. Festivali "Panorama Special" kavas olnud Peeter Simmi "Head käed" saavutas hea publikuedu ning jagas sloveenlase Maja Weiss'i filmiga "Piirivalvur" Manfred Salzgeberi auhinda, mis on mõeldud subtiitrite tegemiseks filmi levitamisel euroopa ekraanidele. Kuldkaru jagasid briti Paul Greengrassi "Verine pühapäev" ja jaapanlase Hayao Miyazaki animafilm "Vaimudest viidud". Elutöö-Kuldkarud said Claudia Cardinale ja Robert Altman

  5. Corelli Music Sügis 2008 - Jaapanist Veneetsiani

    Index Scriptorium Estoniae

    2008-01-01

    Jaapani klavessinistist Yoshiko Iekist, kontsertidest 8. sept. Tallinnas ja 10. sept. Maardu mõisas sarjas "Maardu mõisa muusikasalong" (Y. Ieki ansamblipartneriks on viiuldaja Mail Sildos). Kava "Vivaldi, Casanova ja Veneetsia" esitusest 15. okt. Maardus sarjas "Maardu mõisa muusikasalong", 18. okt. Pärnu hotellis Victoria sarjas "Café Grand muusikasalong" ja 19. okt. Tallinnas sarjas "Toompea Muusikasalong" (esineb barokkansambel Corelli Consort, kommenteerib kunstnik Raivo Järvi)

  6. Kontserthuset Göteborg. Fredag 7. mars 1997 Stora salen

    Index Scriptorium Estoniae

    1997-01-01

    Kontserthuset Göteborg. Göteborgs Symfoniker. Chefdirigent: Neeme Järvi. Dirigent: Neeme Järvi. Kontsertmästare: Per Enoksson, Christer Thorvaldsson. Fredag 7. mars 1997 Stora salen (orange serie). Kavas: Ingvar Lidholm "Toccata e canto", Eduard Tubin Sümfoonia N 5 h-moll, Igor Stravinski "Püha kevad" Lk. 3-4: Kruckenberg, Sven: Tubin - Symfoni nr 5. Lk. 7 Neeme Järvi dirigenditööst

  7. Eesti Kunstimuuseumi kevadine suurprojekt

    Index Scriptorium Estoniae

    2005-01-01

    6. maist Väliskunsti Muuseumis näitus "Šveitsi muusa. Angelika Kauffmann (1741-1807)". Väljas on Churi (Bündner Kunstmuseum Chur) ja Väliskunsti Muuseumi tööd. Näituse initsiaator ja Šveitsi-poolne korraldaja Giuliano Crivelli, Eesti-poolne kuraator Kadi Polli. Seminari kava 6. V, esinevad Beat Stutzer, Mai Levin, Kadi Polli, Renate Berger, Sirje Kivimäe, Ave Tarrend

  8. Burkholderia pseudomallei Data Gap Analysis

    Science.gov (United States)

    2015-11-01

    Since its discovery , B. pseudomallei has become recognized as a significant public health threat in the tropical regions of the globe where it is...alcoholics, kava users (Australia), chronic drug users, or diabetic. However, HIV does not seem to be a factor. Table 2-1. Published melioidosis...However, the history for these types of vaccines has shown better efficacy in mouse models that in human trials. In addition to the naked-DNA

  9. Kunst ja glamuur ulatavad käe / Jaak Lõhmus

    Index Scriptorium Estoniae

    Lõhmus, Jaak

    2005-01-01

    Cannes'i 58. filmifestival toimub 11.-22. maini. Võistluskavast, esilinastustest (George Lucas'e "Tähesõdade" värske osa) ja žüriist, mida juhib Emir Kusturica. "Režissööride kahe nädala" kavas on ka leedulase Šarunas Bartase "Seitse nähtamatut meest". Võistluskava 20 filmi hulgas pole dokumentaal- ja animafilme

  10. Kaitsevägi hangib iseliikuvaid suurtükke / Andres Einmann

    Index Scriptorium Estoniae

    Einmann, Andres

    2013-01-01

    Kaitseministeerium kulutab tuleval aastal investeeringuteks 43,26 miljonit eurot. Kavas on hankida uut sõjatehnikat: suurtükke ja lahingumasinaid, teine Thales Raytheoni Ground Master 403 tüüpi radar, Sisu XA-188 soomukeid. Suurim projekt on viie kasarmu ehitamine: aasta lõpuks valmivad neli kasarmut Võrus, Jõhvis ja Ämaris ning peale selle renoveeritakse üks hoone Miinisadamas

  11. "Nevidannoje kino"

    Index Scriptorium Estoniae

    2008-01-01

    5.- 8. juunini toimub Maardus ja Tallinnas 8. rahvusvaheline lühifilmide festival "Ennenägematu Film". Tööd on peamiselt noortelt ja filmitudengitelt Eestist, Venemaalt, Lätist, Leedust jm. Seekord on ka eriprogramm "Uvazhajemõi A.P.", mille kava on ära toodud. Filmiprogramm on Anton Tshehhovi loomingust valminud filmidest, mille autoriteks on eri aegadel VGIKis (Üleliiduline Riiklik Kinoinstituut) õppinud režissöörid

  12. Savisaar : Vene suurfirma ei esindanud Eesti huve / Jaanus Piirsalu

    Index Scriptorium Estoniae

    Piirsalu, Jaanus, 1973-

    2006-01-01

    Majandus- ja kommunikatsiooniminister Edgar Savisaar lükkab ümber BRS-i omaniku Edward Burkhardti väited ning teatab, et Severstaltransi üks juhte Andrei Filatov esindas kohtumisel Eesti Raudtee omaniku E. Burkhardtiga ainult oma firma ärihuve, kui ta soovitas müüa raudtee Eesti riigile. Minister peab võimalikuks, et BRS-il oli algusest peale kavas müüa raudtee Vene firmadele. Lisa: Severstaltransi soovitus

  13. Inimene Pallases

    Index Scriptorium Estoniae

    1999-01-01

    22. okt.-st Tartu Kunstimajas kõrgema kunstikooli 'Pallas' 80. aastapäevale pühendatud ideenäitus 'Inimene on inimene'. Väljas on 20 maali, 43 graafilist lehte, üks skulptuur Ferdi Sannamehelt. Kuraator Kaire Nurk. 4. XI Tartu Kunstimajas toimuva 'Pallase' kooli aastapäevale pühendatud vabakunsti õpetamise potensiaale ja probleeme käsitleva konverentsi kava, esinejad

  14. Tudengid tulid appi / Kaupo Kala ; kommenteerinud Heikki Zoova

    Index Scriptorium Estoniae

    Kala, Kaupo

    2010-01-01

    Koristustarvikuid ja -vahendeid tootval ettevõttel KH Teh Production OÜ valmisid koostöös Eesti Kunstiakadeemia tootedisaini osakonnaga ettevõtte tootearendusprojekt, disaini juhtimise kava, uus pakendisüsteem, stiiliraamat, arendati uusi tooteid. Töörühma, kuhu kuulusid neli üliõpilast ja kaks firma töötajat, juhtis EKA tootedisaini osakonna juhataja Heikki Zoova

  15. Hitchcock-happening friikluse võtmes / Jarmo Valkola

    Index Scriptorium Estoniae

    Valkola, Jarmo

    2008-01-01

    Alfred Hitchcockist seoses uue filmisarjaga "Ainult friikidele". Sarja juhatab sisse Balti Filmi- ja Meediakooli (BFMi) Hitchcocki seminar 26.-29. veebruaril Tallinna Kinomajas. Lisatud kava. (Filmisari linastub alates 25. veebruarist igal teisel esmaspäeval kinos Sõprus ja teisipäeval Tartu Athena Keskuses. Programm vältab ligi kuus kuud, 29. juulini. Esimese hooaja teemaks on ühiskondlikud ebakõlad)

  16. Kultuurisuvi

    Index Scriptorium Estoniae

    2007-01-01

    Muusikasündmuste kava: 1. juuni-31. aug. Nargen Festival, 15.-16. juuni festival Rabarock, 16.-23. juuni Suure-Jaani muusikafestival, 29. juuni-1. juuli X Noorte laulu- ja tantsupidu "Ilmapuu lävel", 6. juuli-9.aug. festival "Klaaspärlimäng", 26.-28. juuli Kuressaare Ooperipäevad, 26.-29. juuli XV Viljandi Pärimusmuusike Festival, 10.-18. aug. Leigo Järvemuusika, 10.-19. aug. Brigitta Festival

  17. Heino Harak : biodiislikütus paisataks Eesti tanklatesse 2006. aasta lõpuks / Heino Harak ; interv. Toivo Tänavsuu

    Index Scriptorium Estoniae

    Harak, Heino, 1941-

    2005-01-01

    Firma Biodiesel suuromanik vastab küsimustele, mis puudutavad biodiislikütuse tehase rajamist, kütuse müüki, tavalise diislikütuse ja biodiislikütuse hinna vahet, Werol Tehaste kava müüa oma osalus Biodieselis, biodiislikütuse võimalikku vabastamist aktsiisimaksust. Diagrammid: Biodiislikütus on aktsiisiga liiga kallis. Lisad: Biodiislikütusest on puudu kogu Euroopas; Kes ta on?

  18. Nizozemska bolest u Bolivarijanskoj Republici Venezueli

    OpenAIRE

    Jošić, Doc. dr. sc. Hrvoje; Maček Pandak, Fran

    2017-01-01

    Venezuela je od svog osamostaljenja gospodarstvo temeljila na proizvodnji i izvozu jednog proizvoda. U 19. stoljeću to su bili kava i kakaovac koje je u 20. stoljeću zamijenila nafta. Navedeno je dovelo do nizozemske bolesti koja je gušila ostale gospodarske grane, pa su često korumpirane vlasti kupovale socijalni mir socijalističkim politikama i državnom potrošnjom. 1980-ih došlo je do prvog značajnijeg pada cijene nafte u 20. stoljeću te je Venezuela morala provesti liberalne reforme kako b...

  19. Cytochrome P450 enzyme mediated herbal drug interactions (Part 2)

    Science.gov (United States)

    Wanwimolruk, Sompon; Phopin, Kamonrat; Prachayasittikul, Virapong

    2014-01-01

    To date, a number of significant herbal drug interactions have their origins in the alteration of cytochrome P450 (CYP) activity by various phytochemicals. Among the most noteworthy are those involving St. John's wort and drugs metabolized by human CYP3A4 enzyme. This review article is the continued work from our previous article (Part 1) published in this journal (Wanwimolruk and Prachayasittikul, 2014[ref:133]). This article extends the scope of the review to six more herbs and updates information on herbal drug interactions. These include black cohosh, ginseng, grape seed extract, green tea, kava, saw palmetto and some important Chinese medicines are also presented. Even though there have been many studies to determine the effects of herbs and herbal medicines on the activity of CYP, most of them were in vitro and in animal studies. Therefore, the studies are limited in predicting the clinical relevance of herbal drug interactions. It appeared that the majority of the herbal medicines have no clear effects on most of the CYPs examined. For example, the existing clinical trial data imply that black cohosh, ginseng and saw palmetto are unlikely to affect the pharmacokinetics of conventional drugs metabolized by human CYPs. For grape seed extract and green tea, adverse herbal drug interactions are unlikely when they are concomitantly taken with prescription drugs that are CYP substrates. Although there were few clinical studies on potential CYP-mediated interactions produced by kava, present data suggest that kava supplements have the ability to inhibit CYP1A2 and CYP2E1 significantly. Therefore, caution should be taken when patients take kava with CYP1A2 or CYP2E1 substrate drugs as it may enhance their therapeutic and adverse effects. Despite the long use of traditional Chinese herbal medicines, little is known about the potential drug interactions with these herbs. Many popularly used Chinese medicines have been shown in vitro to significantly change the

  20. Muusika : Juubelikontserdid "ERSO 75". Tüür uuel CD-l. Muusikakonverentsid Tallinnas. Highlightsi festivalist "Eduard Tubin ja tema aeg". Hermanni päev / Vardo Rumessen

    Index Scriptorium Estoniae

    Rumessen, Vardo, 1942-2015

    2001-01-01

    ERSO saab detsembris 75. aastaseks ja sel puhul on kavas kontserdid nii Tartus kui Tallinnas. Ansambel Piano Circus on välja antud uue CD, millele annab nime avateos ئ Erkki-Sven Tüüri "Transmission". Eesti Muusikateaduse Selts korraldab 3.XII EMA-s sümpoosioni teemal Beethoveni muusika. 1. ja 2. XII EMA-s toimub konverents "Interpretatsioonipedagoogika probleeme II". Põhjamaade muusikaajakirja Highlights XI numbris ilmus ülevaade rahvusvahelisest muusikafestivalist "Eduard Tubin ja tema aeg". Eesti teatri- ja muusikamuuseumis toimub helilooja, ajakirjaniku, muusika- ja keeleteadlase, dr. Karl August Hermanni päev

  1. Uudised : Tüür Frankfurdi "Auftaktil". Motörhead ja Manson Soomes

    Index Scriptorium Estoniae

    2007-01-01

    Frankfurdi Vana Ooperi uut hooaega traditsiooniliselt sissejuhatava festivali "Auftakt" tänavusteks külalisteks on Erkki-Sven Tüür ja inglise tšellist Steven Isserlis, 28. aug.-1. okt. kestval festivalil mängitakse Tüüri 6. ja 7. (4. sümfooniat dirigeerib Paavo Järvi), 12. sept. kavas "Fata Morgana" ja "Oxymoron" ning Helena Tulve "Lumineux..." Olari Eltsi juhatusel. Inglise ansambli Motörhead kontserdist 11. dets. ja USA rokkari Marilyn Mansoni kontserdist 20. dets. Helsingis

  2. Ärimees Armin Karult raha nõudnud "rullnokad" toimetasid politsei nina all / Rasmus Kagge, Risto Berendson

    Index Scriptorium Estoniae

    Kagge, Rasmus, 1977-

    2008-01-01

    Ilmunud ka: Postimees : na russkom jazõke 17. jaan. 2008, lk. 2-3. Raplamaa noorukeid Ardot ja Viljarit kahtlustatakse kasiinoärimehe Armin Karu tütre Inese pantvangi võtmise kava sepistamises, nad lootsid Olympic Casino keti suuromanikult saada 235 miljonit krooni lunaraha. Politsei tööst kuriteo avastamisel ja nurjamisel. Lisa: Inimröövid. Vt. samas: Armin Karu: kahju, et selliseid tegelasi leidub. Ilmunud ka: samal teemal:Risto Berendsoni art. 18. jaan. Postimees lk. 6; 19. jaan. Postimees ja Postimees : na russkom jazõke lk. 5 ja lk. 3

  3. Gynecology: select topics.

    Science.gov (United States)

    Sidani, Mohamad; Campbell, James

    2002-06-01

    Menopause, premenstrual syndrome, dysmenorrhea, female fertility, and mastalgia are common problems not easily treated by conventional medicine. Women often seek alternative therapies to help address these conditions. Some evidence points to the efficacy of black cohosh, exercise, and possibly Kava and St. John's wort, in the treatment of menopausal symptoms. Clinical trials indicate that symptoms of premenstrual syndrome may be alleviated with calcium, magnesium, vitamin E. Thiamine, omega-3 fatty acids, the Japanese herbal concoction, TSS, and calcium have proved useful in treating women with dysmenorrhea. Symptoms of mastalgia may be attenuated by evening primrose oil, chaste tree and flaxseed oil may be helpful.

  4. Maaleht soovitab : Anu Tali dirigeerib Vanemuises "Toscat". Vivaldi, Casanova ja Veneetsia. "Uinuv kaunitar" Vanemuises. Andrew Lloyd Webberi juubelikontserdid. Pärimusmuusika lõiluspidu

    Index Scriptorium Estoniae

    2008-01-01

    27. sept. juhatab Anu Tali Vanemuise teatris Mikk Mikiveri lavastatud ja Ervin Õunapuu taastatud Puccini ooperilavastust "Tosca". Barokkansambel Corelli Consort ja Raivo Järvi esitavad kava "Vivaldi, Casanova ja Veneetsia" 15. okt. Maardu mõisa muusikasalongis, 18. okt. Pärnus sarjas "Café Grand muusikasalong" ja 19. okt. Eesti Teaduste Akadeemia majas sarjas "Toompea muusikasalong". Vanemuisees esietendub 4. okt. Pjotr Tshaikovski ballett "Uinuv kaunitar". Tallinnas Saku Suurhallis toimuvad 18. okt. briti muusikalihelilooja Andrew Lloyd Webberi 60. sünnipäevale pühendatud juubelikontserdid. Viljandi Pärimusmuusika Aidas peetakse 10.-11. okt. "Pärimusmuusika lõikuspidu"

  5. Uudised : Georg Ots 80. "Pärt in Profile" Londonis. Kaljuste taas esile tõstetud. Paavo Järvi eesti muusikaga La Scalas / Priit Kuusk

    Index Scriptorium Estoniae

    Kuusk, Priit, 1938-

    2000-01-01

    G. Otsa 80. sünniaastapäeva tähistamisest G. Otsa nim. Tallinna Muusikakoolis ئ avati G. Otsa muuseum. 28.-31. märtsini Londonis toimuvast muusikafestivalist "Pärt in Profile", kus tutvustatakse A. Pärdi jt. eesti heliloojate loomingut. T. Kaljuste on Edison Classical Music Awards 2000 nominentide seas koorimuusika kategoorias kahel korral. P. Järvi juhatas 28. veebr. Milano La Scala orkestrit, kavas A. Pärdi "Cantus in memoriam Benjamin Britten", dirigendi tegemistest märtsis

  6. Efficacy and safety of herbal stimulants and sedatives in sleep disorders.

    Science.gov (United States)

    Gyllenhaal, Charlotte; Merritt, Sharon L.; Peterson, Sara Davia; Block, Keith I.; Gochenour, Tom

    2000-06-01

    World-wide use of herbal medicines is increasing, following regulatory and manufacturing developments. Herbs are attractive alternative medications to many patients with sleep disorders, who may be averse to using conventional drugs. We review here the most common herbal stimulants and sedatives. Caffeine, in herbal teas, black tea, coffee, soft drinks and pharmaceuticals, is used widely to control sleepiness, but more research is needed on its use in sleep disorders. Ephedra, and its constituent ephedrine, are used in both stimulant and weight loss preparations, sometimes with caffeine; safety concerns have arisen with this practice. Yohimbe is another herb used in stimulant and body-building preparations which has safety concerns. Asian and Siberian ginseng have been traditionally used for fatigue, and have some supportive experimental evidence for this use. Herbal sedatives also have some evidence for efficacy; the observations that certain plant flavonoid compounds bind to benzodiazepine receptors adds interest to their use. Valerian and kava have received the most research attention; both have decreased sleep onset time and promoted deeper sleep in small studies, and kava also shows anxiolytic effects. German chamomile, lavender, hops, lemon balm and passionflower are reputed to be mild sedatives but need much more experimental examination.

  7. Herbal medicine for insomnia: A systematic review and meta-analysis.

    Science.gov (United States)

    Leach, Matthew J; Page, Amy T

    2015-12-01

    Insomnia is a prevalent sleep disorder that can profoundly impact a person's health and wellbeing. Herbal medicine represents one of the most frequently used complementary and alternative treatments of insomnia. However, the safety and efficacy of herbal medicine for the treatment of this disorder is currently uncertain. In order to ascertain the evidence base for herbal medicine for insomnia, we systematically searched seventeen electronic databases and the reference lists of included studies for relevant randomised controlled trials (RCTs). Fourteen RCTs, involving a total of 1602 participants with insomnia, met the inclusion criteria. Four distinct orally administered herbal monopreparations were identified (i.e., valerian, chamomile, kava and wuling). There was no statistically significant difference between any herbal medicine and placebo, or any herbal medicine and active control, for any of the thirteen measures of clinical efficacy. As for safety, a similar or smaller number of adverse events per person were reported with kava, chamomile and wuling when compared with placebo. By contrast, a greater number of events per person were reported with valerian. While there is insufficient evidence to support the use of herbal medicine for insomnia, there is a clear need for further research in this area. Copyright © 2014 Elsevier Ltd. All rights reserved.

  8. A comparative study of amplitude calibrations for the East Asia VLBI Network: A priori and template spectrum methods

    Science.gov (United States)

    Cho, Ilje; Jung, Taehyun; Zhao, Guang-Yao; Akiyama, Kazunori; Sawada-Satoh, Satoko; Kino, Motoki; Byun, Do-Young; Sohn, Bong Won; Shibata, Katsunori M.; Hirota, Tomoya; Niinuma, Kotaro; Yonekura, Yoshinori; Fujisawa, Kenta; Oyama, Tomoaki

    2017-12-01

    We present the results of a comparative study of amplitude calibrations for the East Asia VLBI Network (EAVN) at 22 and 43 GHz using two different methods of an "a priori" and a "template spectrum", particularly on lower declination sources. Using observational data sets of early EAVN observations, we investigated the elevation-dependence of the gain values at seven stations of the KaVA (KVN and VERA Array) and three additional telescopes in Japan (Takahagi 32 m, Yamaguchi 32 m, and Nobeyama 45 m). By comparing the independently obtained gain values based on these two methods, we found that the gain values from each method were consistent within 10% at elevations higher than 10°. We also found that the total flux densities of two images produced from the different amplitude calibrations were in agreement within 10% at both 22 and 43 GHz. By using the template spectrum method, furthermore, the additional radio telescopes can participate in KaVA (i.e., EAVN), giving a notable sensitivity increase. Therefore, our results will constrain the detailed conditions in order to measure the VLBI amplitude reliably using EAVN, and discuss the potential of possible expansion to telescopes comprising EAVN.

  9. High throughput Screening to Identify Natural Human Monoamine Oxidase B Inhibitors

    Science.gov (United States)

    Mazzio, E; Deiab, S; Park, K; Soliman, KFA

    2012-01-01

    Age-related increase in monoamine oxidase B (MAO-B) may contribute to CNS neurodegenerative diseases. Moreover, MAO-B inhibitors are used in the treatment of idiopathic Parkinson disease as preliminary monotherapy or adjunct therapy with L-dopa. To date, meager natural sources of MAO-B inhibitors have been identified, and the relative strength, potency and rank of many plants relative to standard drugs such as Selegiline (L-deprenyl, Eldepryl) are not known. In this work, we developed and utilized a high throughput enzyme microarray format to screen and evaluate 905 natural product extracts (0.025–.7 mg/ml) to inhibit human MAO-B derived from BTI-TN-5B1-4 cells infected with recombinant baculovirus. The protein sequence of purified enzyme was confirmed using 1D gel electrophoresis-matrix assisted laser desorption ionization-time-of-flight-tandem mass spectroscopy, and enzyme activity was confirmed by [1] substrate conversion (3-mM benzylamine) to H202 and [2] benzaldehyde. Of the 905 natural extracts tested, the lowest IC50s [Comfrey, Bringraj, Skullcap, Kava-kava, Wild Indigo, Gentian and Green Tea. In conclusion, the data reflect relative potency information by rank of commonly used herbs and plants that contain human MAO-B inhibitory properties in their natural form. PMID:22887993

  10. Лабораторные работы / Борис Тух ; иллюстрация: Cheng Chu

    Index Scriptorium Estoniae

    Тух, Борис, 1946-

    2013-01-01

    5.-6. okt. 2013 toimus Tallinnas Vene Teatris, Teatris NO99 ja Von Krahli Teatris uue vene dramaturgia laboratoorium ("Лаборатория современной российской драматургии"). Kavas olid järgmised lavastuseskiisid: Ivan Võrõpajevi "Illusioonid" (lav. Pavel Zobnin), Pavel Prjažko "Alukad" (lav. Anton Malikov), Pavel Prjažko "Põld" (lav. Ivar Põllu), Mihhail Durnenkovi "(Kõige) lihtsam meetod suitsetamisest loobumiseks" (lav. Ivan Strelkin). Näidendid ja lavastajad valis Vene Teatri peanäitejuht Marat Katsalov

  11. Vanadust käsitlev projekt Tallinna Kunstihoones

    Index Scriptorium Estoniae

    2005-01-01

    Tallinna Kunstihoones Reet Varblase kureeritud näitus "Homo grandis natu", mis käsitleb vanaduse ja vananemise tähendust ja rolli praeguses ühiskonnas. Osalejaid: Boaz Tal, Eveli Varik, Ly Lestberg, Mare Mikof, Aili Vahtrapuu, Jaan Paavle, Terje Ojaver, Marge Monko, Terje Tunis, Tatjana Antoshina, Valeri Vinogradov, Peeter Laurits, Toomas Kalve, Jüri Ojaver. 15. IV toimuva seminari "Eesti vananemispoliitika täna ja homme" ning 21., 28. IV, 5., 12. V toimuva loengusarja kava. 16. IV peab Boaz Tal loengu arhetüüpidest ja mälust, tutvustab oma töid. 21. IV avatakse Katarzyna Kozyra videoinstallatsioon "Naiste saun". 2. V performance'i-festival "Diverse universe", loetletud osalejaid

  12. Emotional Expression in Reality TV

    DEFF Research Database (Denmark)

    Rasmussen, Tove Arendt

    Reality TV has been disputed and discussed along many lines for the last 20 years; the media themselves always with a twist of concern about reality programs crossing moral borderlines while research has put more interest in questions of genre and representation of more or less useful and maybe...... empowering social identities. In the latest generation of reality TV which Misha Kava has described as the “celebrity generation”, it seems that reality creates new standards for mixing facts and fiction and even different “realities” as participants become media stars while more traditional celebrities...... are being treated as ordinary people. My article will discuss different presentations of selves and especially the emotional verbal and nonverbal expressions in reality TV communication. Aspects of the intimate self and its emotional expressions seem to be strategically managed in reality TV and even...

  13. A primer of complementary and alternative medicine commonly used by cancer patients.

    Science.gov (United States)

    Ernst, E

    2001-01-15

    Complementary and alternative medicine (CAM) is frequently used by cancer patients, and many oncologists have limited knowledge of CAM. This article provides a brief, evidence-based introduction to several CAM treatments relevant in the context of cancer. "Alternative" diets, chiropractic, coffee enemas, ozone therapy, and shark cartilage seem to have little to offer cancer patients. The evidence for or against homoeopathy and spiritual healing is at present inconclusive. Acupuncture, aromatherapy, and meditation may be useful for nausea/vomiting, for mild relaxation, and for pain/anxiety, respectively. Herbal treatments offer no reasonable prospect of a cure (mistletoe), but could be useful as palliative treatments (eg, for depression [St John's wort] or anxiety [kava]). Our knowledge regarding the potential benefit and harm of CAM is insufficient.

  14. Beyond Cannabis: Plants and the Endocannabinoid System.

    Science.gov (United States)

    Russo, Ethan B

    2016-07-01

    Plants have been the predominant source of medicines throughout the vast majority of human history, and remain so today outside of industrialized societies. One of the most versatile in terms of its phytochemistry is cannabis, whose investigation has led directly to the discovery of a unique and widespread homeostatic physiological regulator, the endocannabinoid system. While it had been the conventional wisdom until recently that only cannabis harbored active agents affecting the endocannabinoid system, in recent decades the search has widened and identified numerous additional plants whose components stimulate, antagonize, or modulate different aspects of this system. These include common foodstuffs, herbs, spices, and more exotic ingredients: kava, chocolate, black pepper, and many others that are examined in this review. Copyright © 2016 Elsevier Ltd. All rights reserved.

  15. Kadavu Island: adaptation and stagnation in the Fijian periphery

    Directory of Open Access Journals (Sweden)

    Sofer Michael

    2015-06-01

    Full Text Available The outer island of Kadavu is representative of the Fijian periphery. This paper deals with its physical characteristics, infrastructural conditions, and village economic activities with the aim of understanding the changes it has gone through in recent years. A combination of micro-geographic studies in two villages and a meso-geographical analysis show that the pattern of development found in Kadavu in the early 1980s has not changed much. The current pattern of cash crop production and trade is almost entirely dependent on the kava beverage crop, infrastructure is underdeveloped, the island suffers from the peripheral penalty phenomenon, and government initiatives aimed at changing the trend are very limited. However, the current form of non-capitalist production and its derived benefit has forced villagers into a strategy of adaptation which might actually be preferable for them under the current conditions of peripheralization.

  16. An evaluation of selected herbal reference texts and comparison to published reports of adverse herbal events.

    Science.gov (United States)

    Haller, Christine A; Anderson, Ilene B; Kim, Susan Y; Blanc, Paul D

    2002-01-01

    There has been a recent proliferation of medical reference texts intended to guide practitioners whose patients use herbal therapies. We systematically assessed six herbal reference texts to evaluate the information they contain on herbal toxicity. We selected six major herbal references published from 1996 to 2000 to evaluate the adequacy of their toxicological information in light of published adverse events. To identify herbs most relevant to toxicology, we reviewed herbal-related calls to our regional California Poison Control System, San Francisco division (CPCS-SF) in 1998 and identified the 12 herbs (defined as botanical dietary supplements) most frequently involved in these CPCS-SF referrals. We searched Medline (1966 to 2000) to identify published reports of adverse effects potentially related to these same 12 herbs. We scored each herbal reference text on the basis of information inclusiveness for the target 12 herbs, with a maximal overall score of 3. The herbs, identified on the basis of CPCS-SF call frequency were: St John's wort, ma huang, echinacea, guarana, ginkgo, ginseng, valerian, tea tree oil, goldenseal, arnica, yohimbe and kava kava. The overall herbal reference scores ranged from 2.2 to 0.4 (median 1.1). The Natural Medicines Comprehensive Database received the highest overall score and was the most complete and useful reference source. All of the references, however, lacked sufficient information on management of herbal medicine overdose, and several had incorrect overdose management guidelines that could negatively impact patient care. Current herbal reference texts do not contain sufficient information for the assessment and management of adverse health effects of botanical therapies.

  17. An overview of herbal supplement utilization with particular emphasis on possible interactions with dental drugs and oral manifestations.

    Science.gov (United States)

    Abebe, Worku

    2003-01-01

    Herbal medication in the United States is a popular form of therapy. This paper provides an overview of the utilization of herbal supplements with particular emphasis on possible interactions with oral health drugs and oral manifestations. Herbal supplements are regulated by the Dietary Supplement Health and Education Act (DSHEA), which limits their regulation by the U.S Food and Drug Administration (FDA). A number of studies indicate that there is a progressive increase in the utilization of herbal supplements. The majority of consumers of these products are white, middle-aged women who have some college education. Many of the consumers use pharmaceutical drugs concurrently, but most do not inform their health-care providers about their use of herbal supplements. Various herbal supplements have been reported or are suspected to interact with certain oral health drugs, the most important one being 1) bromelain, cayenne, chamomile, feverfew, dong quai, eleuthro/Seberian ginseng, garlic, ginkgo, ginger, ginseng and licorice interacting with aspirin; 2) aloe latex, ephedra, ginseng, rhubarb, cascara sagrada, licorice, and senna interacting with corticosteriods; 3) kava, St. John's wort, chamomile, and valerian interacting with central nervous system (CNS) depressant drugs; and 4) herbs acting on the gastrointestinal system, altering the absorption of several orally administered drugs. Further, the use of some herbal supplements has been reported to be associated with oral manifestations, including aphthous ulcers, lip and tongue irritation, and swelling with feverfew; gingival bleeding with feverfew and ginkgo; tongue numbness with echinacea; xerostomia with St. John's wort; oral and lingual dyskinesia with kava; and salivation with yohimbe. These potential effects of herbal supplements in conjunction with factors related to regulation restrictions suggest that the use of these products may be associated with various adverse reactions that can affect oral health and

  18. Phytochemical Assays of Commercial Botanical Dietary Supplements

    Directory of Open Access Journals (Sweden)

    Robert Krochmal

    2004-01-01

    Full Text Available The growing popularity of botanical dietary supplements (BDS has been accompanied by concerns regarding the quality of commercial products. Health care providers, in particular, have an interest in knowing about product quality, in view of the issues related to herb-drug interactions and potential side effects. This study assessed whether commercial formulations of saw palmetto, kava kava, echinacea, ginseng and St. John's wort had consistent labeling and whether quantities of marker compounds agreed with the amounts stated on the label. We purchased six bottles each of two lots of supplements from nine manufacturers and analyzed the contents using established commercial methodologies at an independent laboratory. Product labels were found to vary in the information provided, such as serving recommendations and information about the herb itself (species, part of the plant, marker compound, etc. With regard to marker compound content, little variability was observed between different lots of the same brand, while the content did vary widely between brands (e.g. total phenolic compounds in Echinacea ranged from 3.9–15.3 mg per serving; total ginsenosides in ginseng ranged from 5.3–18.2 mg per serving. Further, the amounts recommended for daily use also differed between brands, increasing the potential range of a consumer's daily dose. Echinacea and ginseng were the most variable, while St. John's wort and saw palmetto were the least variable. This study highlights some of the key issues in the botanical supplement market, including the importance of standardized manufacturing practices and reliable labeling information. In addition, health care providers should keep themselves informed regarding product quality in order to be able to appropriately advise patients utilizing both conventional and herbal medicines.

  19. Commonly Used Dietary Supplements on Coagulation Function during Surgery

    Directory of Open Access Journals (Sweden)

    Chong-Zhi Wang

    2015-07-01

    Full Text Available Background: Patients who undergo surgery appear to use dietary supplements significantly more frequently than the general population. Because they contain pharmacologically active compounds, dietary supplements may affect coagulation and platelet function during the perioperative period through direct effects, pharmacodynamic interactions, and pharmacokinetic interactions. However, in this regard, limited studies have been conducted that address the pharmacological interactions of dietary supplements. To avoid possible bleeding risks during surgery, information about the potential complications of dietary supplements during perioperative management is important for physicians. Methods: Through a systematic database search of all available years, articles were identified in this review if they included dietary supplements and coagulation/platelet function, while special attention was paid to studies published after 1990. Results: Safety concerns are reported in commercially available dietary supplements. Effects of the most commonly used natural products on blood coagulation and platelet function are systematically reviewed, including 11 herbal medicines (echinacea, ephedra, garlic, ginger, ginkgo, ginseng, green tea, kava, saw palmetto, St John’s wort, and valerian and four other dietary supplements (coenzyme Q10, glucosamine and chondroitin sulfate, fish oil, and vitamins. Bleeding risks of garlic, ginkgo, ginseng, green tea, saw palmetto, St John’s wort, and fish oil are reported. Cardiovascular instability was observed with ephedra, ginseng, and kava. Pharmacodynamic and pharmacokinetic interactions between dietary supplements and drugs used in the perioperative period are discussed. Conclusions: To prevent potential problems associated with the use of dietary supplements, physicians should be familiar with the perioperative effects of commonly used dietary supplements. Since the effects of dietary supplements on coagulation and platelet

  20. Commonly Used Dietary Supplements on Coagulation Function during Surgery

    Science.gov (United States)

    Wang, Chong-Zhi; Moss, Jonathan; Yuan, Chun-Su

    2015-01-01

    Abstract Background Patients who undergo surgery appear to use dietary supplements significantly more frequently than the general population. Because they contain pharmacologically active compounds, dietary supplements may affect coagulation and platelet function during the perioperative period through direct effects, pharmacodynamic interactions, and pharmacokinetic interactions. However, in this regard, limited studies have been conducted that address the pharmacological interactions of dietary supplements. To avoid possible bleeding risks during surgery, information about the potential complications of dietary supplements during perioperative management is important for physicians. Methods Through a systematic database search of all available years, articles were identified in this review if they included dietary supplements and coagulation/platelet function, while special attention was paid to studies published after 1990. Results Safety concerns are reported in commercially available dietary supplements. Effects of the most commonly used natural products on blood coagulation and platelet function are systematically reviewed, including 11 herbal medicines (echinacea, ephedra, garlic, ginger, ginkgo, ginseng, green tea, kava, saw palmetto, St John’s wort, and valerian) and four other dietary supplements (coenzyme Q10, glucosamine and chondroitin sulfate, fish oil, and vitamins). Bleeding risks of garlic, ginkgo, ginseng, green tea, saw palmetto, St John’s wort, and fish oil are reported. Cardiovascular instability was observed with ephedra, ginseng, and kava. Pharmacodynamic and pharmacokinetic interactions between dietary supplements and drugs used in the perioperative period are discussed. Conclusions To prevent potential problems associated with the use of dietary supplements, physicians should be familiar with the perioperative effects of commonly used dietary supplements. Since the effects of dietary supplements on coagulation and platelet function are

  1. Phytochemical Assays of Commercial Botanical Dietary Supplements

    Science.gov (United States)

    2004-01-01

    The growing popularity of botanical dietary supplements (BDS) has been accompanied by concerns regarding the quality of commercial products. Health care providers, in particular, have an interest in knowing about product quality, in view of the issues related to herb-drug interactions and potential side effects. This study assessed whether commercial formulations of saw palmetto, kava kava, echinacea, ginseng and St. John's wort had consistent labeling and whether quantities of marker compounds agreed with the amounts stated on the label. We purchased six bottles each of two lots of supplements from nine manufacturers and analyzed the contents using established commercial methodologies at an independent laboratory. Product labels were found to vary in the information provided, such as serving recommendations and information about the herb itself (species, part of the plant, marker compound, etc.) With regard to marker compound content, little variability was observed between different lots of the same brand, while the content did vary widely between brands (e.g. total phenolic compounds in Echinacea ranged from 3.9–15.3 mg per serving; total ginsenosides in ginseng ranged from 5.3–18.2 mg per serving). Further, the amounts recommended for daily use also differed between brands, increasing the potential range of a consumer's daily dose. Echinacea and ginseng were the most variable, while St. John's wort and saw palmetto were the least variable. This study highlights some of the key issues in the botanical supplement market, including the importance of standardized manufacturing practices and reliable labeling information. In addition, health care providers should keep themselves informed regarding product quality in order to be able to appropriately advise patients utilizing both conventional and herbal medicines. PMID:15841264

  2. Commonly Used Dietary Supplements on Coagulation Function during Surgery.

    Science.gov (United States)

    Wang, Chong-Zhi; Moss, Jonathan; Yuan, Chun-Su

    2015-09-01

    Patients who undergo surgery appear to use dietary supplements significantly more frequently than the general population. Because they contain pharmacologically active compounds, dietary supplements may affect coagulation and platelet function during the perioperative period through direct effects, pharmacodynamic interactions, and pharmacokinetic interactions. However, in this regard, limited studies have been conducted that address the pharmacological interactions of dietary supplements. To avoid possible bleeding risks during surgery, information of potential complications of dietary supplements during perioperative management is important for physicians. Through a systematic database search of all available years, articles were identified in this review if they included dietary supplements and coagulation/platelet function, while special attention was paid to studies published after 1990. Safety concerns are reported in commercially available dietary supplements. Effects of the most commonly used natural products on blood coagulation and platelet function are systematically reviewed, including 11 herbal medicines (echinacea, ephedra, garlic, ginger, ginkgo, ginseng, green tea, kava, saw palmetto, St John's wort, and valerian) and 4 other dietary supplements (coenzyme Q 10 , glucosamine and chondroitin sulfate, fish oil, and vitamins). Bleeding risks of garlic, ginkgo, ginseng, green tea, saw palmetto, St John's wort, and fish oil are reported. Cardiovascular instability was observed with ephedra, ginseng, and kava. Pharmacodynamic and pharmacokinetic interactions between dietary supplements and drugs used in the perioperative period are discussed. To prevent potential problems associated with the use of dietary supplements, physicians should be familiar with the perioperative effects of commonly used dietary supplements. Since the effects of dietary supplements on coagulation and platelet function are difficult to predict, it is prudent to advise their

  3. Flavokawain A induces apoptosis in MCF-7 and MDA-MB231 and inhibits the metastatic process in vitro.

    Directory of Open Access Journals (Sweden)

    Nadiah Abu

    Full Text Available The kava-kava plant (Piper methsyticum is traditionally known as the pacific elixir by the pacific islanders for its role in a wide range of biological activities. The extract of the roots of this plant contains a variety of interesting molecules including Flavokawain A and this molecule is known to have anti-cancer properties. Breast cancer is still one of the leading diagnosed cancers in women today. The metastatic process is also very pertinent in the progression of tumorigenesis.MCF-7 and MDA-MB231 cells were treated with several concentrations of FKA. The apoptotic analysis was done through the MTT assay, BrdU assay, Annexin V analysis, cell cycle analysis, JC-1 mitochondrial dye, AO/PI dual staining, caspase 8/9 fluorometric assay, quantitative real time PCR and western blot. For the metastatic assays, the in vitro scratch assay, trans-well migration/invasion assay, HUVEC tube formation assay, ex vivo rat aortic ring assay, quantitative real time PCR and western blot were employed.We have investigated the effects of FKA on the apoptotic and metastatic process in two breast cancer cell lines. FKA induces apoptosis in both MCF-7 and MDA-MB231 in a dose dependent manner through the intrinsic mitochondrial pathway. Additionally, FKA selectively induces a G2/M arrest in the cell cycle machinery of MDA-MB231 and G1 arrest in MCF-7. This suggests that FKA's anti-cancer activity is dependent on the p53 status. Moreover, FKA also halted the migration and invasion process in MDA-MB231. The similar effects can be seen in the inhibition of the angiogenesis process as well.FKA managed to induce apoptosis and inhibit the metastatic process in two breast cancer cell lines, in vitro. Overall, FKA may serve as a promising candidate in the search of a new anti-cancer drug especially in halting the metastatic process but further in vivo evidence is needed.

  4. Internet marketing of herbal products.

    Science.gov (United States)

    Morris, Charles A; Avorn, Jerry

    2003-09-17

    Passage of the Dietary Supplement Health and Education Act in 1994 restricted the Food and Drug Administration's control over dietary supplements, leading to enormous growth in their promotion. The Internet is often used by consumers as a source of information on such therapies. To assess the information presented and indications claimed on the Internet for the 8 best-selling herbal products. We searched the Internet using the 5 most commonly used search engines. For each, we entered the names of the 8 most widely used herbal supplements (ginkgo biloba, St John's wort, echinacea, ginseng, garlic, saw palmetto, kava kava, and valerian root). We analyzed the health content of all Web sites listed on the first page of the search results. We analyzed all accessible, English-language Web sites that pertained to oral herbal supplements. A total of 522 Web sites were identified; of these, 443 sites met inclusion criteria for the analysis. The nature of the Web site (retail or nonretail), whether it was a sponsored link, and all references, indications, claims, and disclaimers were recorded. Two reviewers independently categorized medical claims as disease or nondisease according to Food and Drug Administration criteria. Among 443 Web sites, 338 (76%) were retail sites either selling product or directly linked to a vendor. A total of 273 (81%) of the 338 retail Web sites made 1 or more health claims; of these, 149 (55%) claimed to treat, prevent, diagnose, or cure specific diseases. More than half (153/292; 52%) of sites with a health claim omitted the standard federal disclaimer. Nonretail sites were more likely than retail sites to include literature references, although only 52 (12%) of the 443 Web sites provided referenced information without a link to a distributor or vendor. Consumers may be misled by vendors' claims that herbal products can treat, prevent, diagnose, or cure specific diseases, despite regulations prohibiting such statements. Physicians should be

  5. Oral administration of methysticin improves cognitive deficits in a mouse model of Alzheimer's disease

    Directory of Open Access Journals (Sweden)

    Athanassios Fragoulis

    2017-08-01

    and reduces neuroinflammation, hippocampal oxidative damage and memory loss in a mouse model of AD. Therefore, kavalactones might be suitable candidates to serve as lead compounds for the development of a new class of neuroprotective drugs. Keywords: Methysticin, Kavalactone, Kava kava, Nrf2, Alzheimer's disease, Neuroinflammation, Astrogliosis, Oxidative stress

  6. Biological Reactive Intermediates (BRIs) Formed from Botanical Dietary Supplements

    Science.gov (United States)

    Dietz, Birgit M.; Bolton, Judy L.

    2013-01-01

    The use of botanical dietary supplements is increasingly popular, due to their natural origin and the perceived assumption that they are safer than prescription drugs. While most botanical dietary supplements can be considered safe, a few contain compounds, which can be converted to reactive biological reactive intermediates (BRIs) causing toxicity. For example, sassafras oil contains safrole, which can be converted to a reactive carbocation forming genotoxic DNA adducts. Alternatively, some botanical dietary supplements contain stable BRIs such as simple Michael acceptors that react with chemosensor proteins such as Keap1 resulting in induction of protective detoxification enzymes. Examples include curcumin from turmeric, xanthohumol from hops, and Z-ligustilide from dang gui. Quinones (sassafras, kava, black cohosh), quinone methides (sassafras), and epoxides (pennyroyal oil) represent BRIs of intermediate reactivity, which could generate both genotoxic and/or chemopreventive effects. The biological targets of BRIs formed from botanical dietary supplements and their resulting toxic and/or chemopreventive effects are closely linked to the reactivity of BRIs as well as dose and time of exposure. PMID:20970412

  7. Botanical modulation of menopausal symptoms: Mechanisms of action?

    Science.gov (United States)

    Hajirahimkhan, Atieh; Dietz, Birgit M.; Bolton, Judy L.

    2013-01-01

    Menopausal women suffer from a variety of symptoms, including hot flashes and night sweats which can affect quality of life. Although hormone therapy (HT) has been the treatment of choice for relieving these symptoms, HT has been associated with increased breast cancer risk leading many women to search for natural, efficacious, and safe alternatives such as botanical supplements. Data from clinical trials suggesting that botanicals have efficacy for menopausal symptom relief, have been controversial and several mechanisms of action have been proposed including estrogenic, progestogenic, and serotonergic pathways. Plant extracts with potential estrogenic activities include soy, red clover, kudzu, hops, licorice, rhubarb, yam, and chasteberry. Botanicals with reported progestogenic activities are red clover, hops, yam, and chasteberry. Serotonergic mechanisms have also been proposed since women taking antidepressants often report reduction in hot flashes and night sweats. Black cohosh, kudzu, kava, licorice, and dong quai all either have reported 5-HT7 ligands or inhibit serotonin re-uptake, therefore have potential serotonergic activities. Understanding the mechanisms of action of these natural remedies used for women’s health, could lead to more efficacious formulations and to the isolation of active components which have the potential of becoming effective medications in the future. PMID:23408273

  8. Drug-botanical interactions: a review of the laboratory, animal, and human data for 8 common botanicals.

    Science.gov (United States)

    Shord, Stacy S; Shah, Kanan; Lukose, Alvina

    2009-09-01

    Many Americans use complementary and alternative medicine (CAM) to prevent or alleviate common illnesses, and these medicines are commonly used by individuals with cancer.These medicines or botanicals share the same metabolic and transport proteins, including cytochrome P450 enzymes (CYP), glucuronosyltransferases (UGTs), and P-glycoprotein (Pgp), with over-the-counter and prescription medicines increasing the likelihood of drug-botanical interactions.This review provides a brief description of the different proteins, such as CYPs, UGTs, and Pgp.The potential effects of drug-botanical interactions on the pharmacokinetics and pharmacodynamics of the drug or botanical and a summary of the more common models used to study drug metabolism are described.The remaining portion of this review summarizes the data extracted from several laboratory, animal, and clinical studies that describe the metabolism, transport, and potential interactions of 8 selected botanicals. The 8 botanicals include black cohosh, Echinacea, garlic, Gingko biloba, green tea, kava, milk thistle, and St John's wort; these botanicals are among some of the more common botanicals taken by individuals with cancer.These examples are included to demonstrate how to interpret the different studies and how to use these data to predict the likelihood of a clinically significant drug-botanical interaction.

  9. Revision and Microtomography of the Pheidole knowlesi Group, an Endemic Ant Radiation in Fiji (Hymenoptera, Formicidae, Myrmicinae)Myrmicinae).

    Science.gov (United States)

    Fischer, Georg; Sarnat, Eli M; Economo, Evan P

    2016-01-01

    The Fijian islands, a remote archipelago in the southwestern Pacific, are home to a number of spectacular endemic radiations of plants and animals. Unlike most Pacific archipelagos, these evolutionary radiations extend to social insects, including ants. One of the most dramatic examples of ant radiation in Fiji has occurred in the hyperdiverse genus Pheidole. Most of the 17 native Fijian Pheidole belong to one of two species groups that descended from a single colonization, yet have evolved dramatically contrasting morphologies: the spinescent P. roosevelti species group, and the more morphologically conservative P. knowlesi species group. Here we revise the knowlesi group, in light of recent phylogenetic results, and enhanced with modern methods of X-ray microtomography. We recognize six species belonging to this group, including two of which we describe as new: Pheidole caldwelli Mann, Pheidole kava sp. n., Pheidole knowlesi Mann, P. ululevu sp. n., P. vatu Mann, and P. wilsoni Mann. Detailed measurements and descriptions, identification keys, and high-resolution images for queens, major and minor workers are provided. In addition, we include highly detailed 3D surface reconstructions for all available castes.

  10. Liver toxicity related to herbs and dietary supplements: Online table of case reports. Part 2 of 5 series.

    Science.gov (United States)

    Brown, Amy Christine

    2017-09-01

    No online current list of potentially life-threatening, hepatotoxic herbs and dietary supplements based on PubMed case reports exists in a summarized tabular form. Documented case reports of herbs or dietary supplements (DS; includes herbs) appearing to contribute to liver injury were used to create an online "DS Toxic Table" of potentially hepatotoxic herbs and dietary supplements (PubMed, 1966 to June, 2016, and cross-referencing). The spectrum of DS induced liver injuries (DSILI) included elevated liver enzymes, hepatitis, steatosis, cholestasis, hepatic necrosis, hepatic fibrosis, hepatic cirrhosis, veno-occlusive disease, acute liver failure requiring a liver transplant, and death. Over the past 50 years, approximately 21 herbs (minus germander and usnic acid that are no longer sold) and 12 dietary supplements (minus the nine no longer sold and vitamin A & niacin due to excess intake) posed a possible risk for liver injures in certain individuals. The herbs with the most number of reported publications (but not cases studies) in descending order, were germander, black cohosh, kava extract, and green tea extract. These online DS Toxic Tables will contribute to continued Phase IV post marketing surveillance to detect possible liver toxicity cases and serve to forewarn consumers, clinicians, and corporations. Copyright © 2017 Elsevier Ltd. All rights reserved.

  11. Review article: herbal and dietary supplement hepatotoxicity.

    Science.gov (United States)

    Bunchorntavakul, C; Reddy, K R

    2013-01-01

    Herbal and dietary supplements are commonly used throughout the World. There is a tendency for underreporting their ingestion by patients and the magnitude of their use is underrecognised by Physicians. Herbal hepatotoxicity is not uncommonly encountered, but the precise incidence and manifestations have not been well characterised. To review the epidemiology, presentation and diagnosis of herbal hepatotoxicity. This review will mainly discuss single ingredients and complex mixtures of herbs marketed under a single label. A Medline search was undertaken to identify relevant literature using search terms including 'herbal', 'herbs', 'dietary supplement', 'liver injury', 'hepatitis' and 'hepatotoxicity'. Furthermore, we scanned the reference lists of the primary and review articles to identify publications not retrieved by electronic searches. The incidence rates of herbal hepatotoxicity are largely unknown. The clinical presentation and severity can be highly variable, ranging from mild hepatitis to acute hepatic failure requiring transplantation. Scoring systems for the causality assessment of drug-induced liver injury may be helpful, but have not been validated for herbal hepatotoxicity. Hepatotoxicity features of commonly used herbal products, such as Ayurvedic and Chinese herbs, black cohosh, chaparral, germander, greater celandine, green tea, Herbalife, Hydroxycut, kava, pennyroyal, pyrrolizidine alkaloids, skullcap, and usnic acid, have been individually reviewed. Furthermore, clinically significant herb-drug interactions are also discussed. A number of herbal medicinal products are associated with a spectrum of hepatotoxicity events. Advances in the understanding of the pathogenesis and the risks involved are needed to improve herbal medicine safety. © 2012 Blackwell Publishing Ltd.

  12. Herbal hepatotoxicity: a tabular compilation of reported cases.

    Science.gov (United States)

    Teschke, Rolf; Wolff, Albrecht; Frenzel, Christian; Schulze, Johannes; Eickhoff, Axel

    2012-11-01

    Herbal hepatotoxicity is a field that has rapidly grown over the last few years along with increased use of herbal products worldwide. To summarize the various facets of this disease, we undertook a literature search for herbs, herbal drugs and herbal supplements with reported cases of herbal hepatotoxicity. A selective literature search was performed to identify published case reports, spontaneous case reports, case series and review articles regarding herbal hepatotoxicity. A total of 185 publications were identified and the results compiled. They show 60 different herbs, herbal drugs and herbal supplements with reported potential hepatotoxicity, additional information including synonyms of individual herbs, botanical names and cross references are provided. If known, details are presented for specific ingredients and chemicals in herbal products, and for references with authors that can be matched to each herbal product and to its effect on the liver. Based on stringent causality assessment methods and/or positive re-exposure tests, causality was highly probable or probable for Ayurvedic herbs, Chaparral, Chinese herbal mixture, Germander, Greater Celandine, green tea, few Herbalife products, Jin Bu Huan, Kava, Ma Huang, Mistletoe, Senna, Syo Saiko To and Venencapsan(®). In many other publications, however, causality was not properly evaluated by a liver-specific and for hepatotoxicity-validated causality assessment method such as the scale of CIOMS (Council for International Organizations of Medical Sciences). This compilation presents details of herbal hepatotoxicity, assisting thereby clinical assessment of involved physicians in the future. © 2012 John Wiley & Sons A/S.

  13. Effectiveness of complementary and self-help treatments for anxiety disorders.

    Science.gov (United States)

    Jorm, Anthony F; Christensen, Helen; Griffiths, Kathleen M; Parslow, Ruth A; Rodgers, Bryan; Blewitt, Kelly A

    2004-10-04

    To review the evidence for the effectiveness of complementary and self-help treatments for anxiety disorders. Systematic literature search using PubMed, PsycLit, and the Cochrane Library. 108 treatments were identified and grouped under the categories of medicines and homoeopathic remedies, physical treatments, lifestyle, and dietary changes. We give a description of the 34 treatments (for which evidence was found in the literature searched), the rationale behind the treatments, a review of studies on effectiveness, and the level of evidence for the effectiveness studies. The treatments with the best evidence of effectiveness are kava (for generalised anxiety), exercise (for generalised anxiety), relaxation training (for generalised anxiety, panic disorder, dental phobia and test anxiety) and bibliotherapy (for specific phobias). There is more limited evidence to support the effectiveness of acupuncture, music, autogenic training and meditation for generalised anxiety; for inositol in the treatment of panic disorder and obsessive-compulsive disorder; and for alcohol avoidance by people with alcohol-use disorders to reduce a range of anxiety disorders.

  14. The Psychopharmacology Algorithm Project at the Harvard South Shore Program: An Algorithm for Generalized Anxiety Disorder.

    Science.gov (United States)

    Abejuela, Harmony Raylen; Osser, David N

    2016-01-01

    This revision of previous algorithms for the pharmacotherapy of generalized anxiety disorder was developed by the Psychopharmacology Algorithm Project at the Harvard South Shore Program. Algorithms from 1999 and 2010 and associated references were reevaluated. Newer studies and reviews published from 2008-14 were obtained from PubMed and analyzed with a focus on their potential to justify changes in the recommendations. Exceptions to the main algorithm for special patient populations, such as women of childbearing potential, pregnant women, the elderly, and those with common medical and psychiatric comorbidities, were considered. Selective serotonin reuptake inhibitors (SSRIs) are still the basic first-line medication. Early alternatives include duloxetine, buspirone, hydroxyzine, pregabalin, or bupropion, in that order. If response is inadequate, then the second recommendation is to try a different SSRI. Additional alternatives now include benzodiazepines, venlafaxine, kava, and agomelatine. If the response to the second SSRI is unsatisfactory, then the recommendation is to try a serotonin-norepinephrine reuptake inhibitor (SNRI). Other alternatives to SSRIs and SNRIs for treatment-resistant or treatment-intolerant patients include tricyclic antidepressants, second-generation antipsychotics, and valproate. This revision of the GAD algorithm responds to issues raised by new treatments under development (such as pregabalin) and organizes the evidence systematically for practical clinical application.

  15. Evaluation of Water consumption and savings achieved in Datacenters through Air side Economization

    Science.gov (United States)

    Mishra, Ravi

    Recent researches and a few facility owners have focused on eliminating the chiller plant altogether by implementing 'Evaporative Cooling', as an alternative or augmentation to compressor-based air conditioning since the energy consumption is dominated by the compressor work (around 41%) in the chiller plant. Because evaporative cooling systems consume water, when evaluating the energy savings potential of these systems, it is imperative to consider not just their impacts on electricity use, but also their impacts on water consumption as well since Joe Kava, Google's head of data center operations, was quoted as saying that water is the "big elephant in the room" for data center companies. The objective of this study was to calculate the savings achieved in water consumption when these evaporative cooling systems were completely or partially marginalized when the facility is strictly working in the Economizer mode also known as 'free cooling' considering other modes of cooling required only for a part of the time when outside temperature, humidity and pollutant level were unfavorable causing improper functioning and reliability issues. The analysis was done on ASHRAE climatic zones with the help of TMY-3 weather data.

  16. Complementary Medicine, Exercise, Meditation, Diet, and Lifestyle Modification for Anxiety Disorders: A Review of Current Evidence

    Directory of Open Access Journals (Sweden)

    J. Sarris

    2012-01-01

    Full Text Available Use of complementary medicines and therapies (CAM and modification of lifestyle factors such as physical activity, exercise, and diet are being increasingly considered as potential therapeutic options for anxiety disorders. The objective of this metareview was to examine evidence across a broad range of CAM and lifestyle interventions in the treatment of anxiety disorders. In early 2012 we conducted a literature search of PubMed, Scopus, CINAHL, Web of Science, PsycInfo, and the Cochrane Library, for key studies, systematic reviews, and metaanalyses in the area. Our paper found that in respect to treatment of generalized anxiety or specific disorders, CAM evidence revealed current support for the herbal medicine Kava. One isolated study shows benefit for naturopathic medicine, whereas acupuncture, yoga, and Tai chi have tentative supportive evidence, which is hampered by overall poor methodology. The breadth of evidence does not support homeopathy for treating anxiety. Strong support exists for lifestyle modifications including adoption of moderate exercise and mindfulness meditation, whereas dietary improvement, avoidance of caffeine, alcohol, and nicotine offer encouraging preliminary data. In conclusion, certain lifestyle modifications and some CAMs may provide a beneficial role in the treatment of anxiety disorders.

  17. Eyelash Epilation in the Absence of Trichiasis: Results of a Population-Based Prevalence Survey in the Western Division of Fiji.

    Science.gov (United States)

    Macleod, Colin; Yalen, Chelsea; Butcher, Robert; Mudaliar, Umesh; Natutusau, Kinisimere; Rainima-Qaniuci, Mere; Haffenden, Chris; Watson, Conall; Cocks, Naomi; Cikamatana, Luisa; Roberts, Chrissy H; Marks, Michael; Rafai, Eric; Mabey, David C W; Kama, Mike; Solomon, Anthony W

    2017-01-01

    The WHO definition of trachomatous trichiasis (TT) is "at least one eyelash touching the globe, or evidence of recent epilation of in-turned eyelashes", reflecting the fact that epilation is used as a self-management tool for TT. In Fiji's Western Division, a high TT prevalence (8.7% in those aged ≥15 years) was reported in a 2012 survey, yet a 2013 survey found no TT and Fijian ophthalmologists rarely see TT cases. Local anecdote suggests that eyelash epilation is a common behaviour, even in the absence of trichiasis. Epilators may have been identified as TT cases in previous surveys. We used a preliminary focus group to design an interview questionnaire, and subsequently conducted a population-based prevalence survey to estimate the prevalence of epilation in the absence of trichiasis, and factors associated with this behaviour, in the Western Division of Fiji. We sampled 695 individuals aged ≥15 years from a total of 457 households in 23 villages. 125 participants (18%) reported epilating their eyelashes at least once within the past year. Photographs were obtained of the eyes of 121/125 (97%) individuals who epilated, and subsequent analysis by an experienced trachoma grader found no cases of trachomatous conjunctival scarring or trichiasis. The age- and sex- adjusted prevalence of epilation in those aged ≥15 years was 8.6% (95% CI 5.7-11.3%). iTaukei ethnicity, female gender, and a higher frequency of drinking kava root were independently associated with epilation. Epilation occurs in this population in the absence of trichiasis, with sufficient frequency to have markedly inflated previous estimates of local TT prevalence. Individuals with epilated eyelashes should be confirmed as having epilated in-turned eyelashes in an eye with scarring of the conjunctiva before being counted as cases of TT.

  18. Utilizing Ayurvedic literature for the identification of novel phytochemical inhibitors of botulinum neurotoxin A.

    Science.gov (United States)

    Yalamanchili, Chinni; Manda, Vamshi K; Chittiboyina, Amar G; Guernieri, Rebecca L; Harrell, William A; Webb, Robert P; Smith, Leonard A; Khan, Ikhlas A

    2017-02-02

    Ayurveda, an ancient holistic system of health care practiced on the Indian subcontinent, utilizes a number of multi-plant formulations and is considered by many as a potential source for novel treatments, as well as the identification of new drugs. Our aim is to identify novel phytochemicals for the inhibition of bacterial exotoxin, botulinum neurotoxin A (BoNT/A) based on Ayurvedic literature. BoNT/A is released by Clostridium species, which when ingested, inhibits the release of acetylcholine by concentrating at the neuromuscular junction and causes flaccid paralysis, resulting in a condition termed as botulism, and may also lead to death due to respiratory arrest. Fifteen plants were selected from the book 'Diagnosis and treatment of diseases in Ayurveda' by Vaidya Bhagwan Dash and Lalitesh Kashyap, based on their frequency of use in the formulations used for the treatment of six diseases with neuromuscular symptoms similar to botulism. Phytochemicals from these plants were screened using in silico, and in vitro methods. Structures of 570 reported phytochemicals from 14 plants were docked inside six reported BoNT/A light chain crystal structures using ensemble docking module in Maestro (Schrödinger, LLE). From the docking scores and structural diversity, nine compounds including acoric acid 1, three flavonoids, three coumarins derivatives, one kava lactone were selected and screened using an in vitro HPLC-based protease assay. The bioassay results showed that several compounds possess BoNT/A LC inhibition of 50-60% when compared to positive controls NSC 84094 and CB7967495 (80-95%). Further testing of the active compounds identified from Ayurvedic literature and structure-activity studies of acoric acid 1 using more sensitive bioassays is under way. The identification of acoric acid 1, a novel scaffold against BoNT/A, exemplifies the utility of Ayurvedic literature for the discovery of novel drug leads. Copyright © 2016 Elsevier Ireland Ltd. All rights

  19. Evaluation of herbal dietary supplements marketed on the internet for recreational use.

    Science.gov (United States)

    Dennehy, Cathi E; Tsourounis, Candy; Miller, Amy E

    2005-10-01

    The Internet is a popular tool for marketing and purchasing herbal dietary supplements (DS). Various Web sites sell these products purely for recreational use. To describe the content of Web sites that advertise and market herbal DS for recreational use (ie, for the purpose of altering mood/behavior/or perception, "getting high," or as a substitute for a drug of abuse). Four major search engines and the search terms "buy herbal high" and "buy legal high" were used to identify Web sites selling herbal DS for recreational use. Web sites were evaluated for their country of origin and for compliance with the Dietary Supplement Health and Education Act (DSHEA). Products were evaluated for their ingredient lists, effect claims, comparisons with illicit drugs, adverse effects, drug interactions, and contraindications. Twenty-eight unique Web sites with 119 products were evaluated. Most sites were in the US (54%) and were in compliance with DSHEA. Forty-seven percent of the products were likened to illicit drugs, typically marijuana (48%) or 3-,4-methylene dioxyamphetamine (Ecstasy; 23%). The most common product ingredients were ephedra alkaloids (27%), Salvia divinorum (17%), kava (10%), guarana (10%), Acorus calamus (10%), and damiana (10%). Effect claims frequently involved the products' use as a hallucinogen (51%) or stimulant (39%). Sixty-four percent of the sites mentioned adverse effects, and 54% mentioned drug interactions. This study demonstrates that herbal DS are being marketed for use as legal alternatives to illicit drugs of abuse. Healthcare professionals need to be aware of this trend and the products that are involved.

  20. Hepatotoxicity of herbal and dietary supplements: an update.

    Science.gov (United States)

    Stickel, Felix; Shouval, Daniel

    2015-06-01

    Herbal and dietary supplements (HDS) have been used for health-related purposes since more than 5000 years, and their application is firmly anchored in all societies worldwide. Over last decades, a remarkable renaissance in the use of HDS can be noticed in affluent societies for manifold reasons. HDS are forms of complementary and alternative medicines commonly used to prevent or treat diseases, or simply as a health tonic. Another growing indication for HDS is their alleged benefit for weight loss or to increase physical fitness. Access is easy via internet and mail-order pharmacies, and their turnover reaches billions of dollars in the USA and Europe alone. However, HDS are generally not categorized as drugs and thus less strictly regulated in most countries. As a result, scientific evidence proving their beneficial effects is mostly lacking, although some HDS may have purported benefits. However, the majority lacks such proof of value, and their use is predominantly based on belief and hope. In addition to missing scientific evidence supporting their use, HDS are typically prone to batch-to-batch variability in composition and concentration, contamination, and purposeful adulteration. Moreover, numerous examples of preparations emerged which have been linked to significant liver injury. These include single ingredients, such as kava, germander, and several Chinese herbals. Other HDS products associated with liver toxicity consist of multiple, often ill-defined ingredients, such as Hydroxycut and Herbalife. Affirmative diagnostic tests are not available, and the assessment of liver injury ascribed to HDS depends on a thorough and proactive medical history, careful exclusion of other causes, and a search for available reports on similar events linked to the intake of the suspected preparation or ingredients contained therein.

  1. Herbal hepatotoxicity: suspected cases assessed for alternative causes.

    Science.gov (United States)

    Teschke, Rolf; Schulze, Johannes; Schwarzenboeck, Alexander; Eickhoff, Axel; Frenzel, Christian

    2013-09-01

    Alternative explanations are common in suspected drug-induced liver injury (DILI) and account for up to 47.1% of analyzed cases. This raised the question of whether a similar frequency may prevail in cases of assumed herb-induced liver injury (HILI). We searched the Medline database for the following terms: herbs, herbal drugs, herbal dietary supplements, hepatotoxic herbs, herbal hepatotoxicity, and herb-induced liver injury. Additional terms specifically addressed single herbs and herbal products: black cohosh, Greater Celandine, green tea, Herbalife products, Hydroxycut, kava, and Pelargonium sidoides. We retrieved 23 published case series and regulatory assessments related to hepatotoxicity by herbs and herbal dietary supplements with alternative causes. The 23 publications comprised 573 cases of initially suspected HILI; alternative causes were evident in 278/573 cases (48.5%). Among them were hepatitis by various viruses (9.7%), autoimmune diseases (10.4%), nonalcoholic and alcoholic liver diseases (5.4%), liver injury by comedication (DILI and other HILI) (43.9%), and liver involvement in infectious diseases (4.7%). Biliary and pancreatic diseases were frequent alternative diagnoses (11.5%), raising therapeutic problems if specific treatment is withheld; pre-existing liver diseases including cirrhosis (9.7%) were additional confounding variables. Other diagnoses were rare, but possibly relevant for the individual patient. In 573 cases of initially assumed HILI, 48.5% showed alternative causes unrelated to the initially incriminated herb, herbal drug, or herbal dietary supplement, calling for thorough clinical evaluations and appropriate causality assessments in future cases of suspected HILI.

  2. Žanr : suvelavastus? / Jaak Allik

    Index Scriptorium Estoniae

    Allik, Jaak, 1946-

    2007-01-01

    Kahekümnest suvisest teatriõhtust: Carlo Gozzi "Ronk" Tallinna Linnateatri lavaaugus (lavastaja Elmo Nüganen), Komöödiateatri suvetuuri lavastus "Elu parim puhkus" (lavastaja Ago-Endrik Kerge), muusikal "Tutvumiskuulutus" (lavastaja Mait Malmsten), Bernard Kangermanni laulumäng "Naabri Mari" (lavastaja Margus Vaher) ja Mara Zalite "Sirelikassid" (lavastaja Peeter Tammearu) Ugalas, Paul Barzi komöödia "Võimalik kohtumine" (lavastaja Raivo Trass) Vanemuise teatri suvelavastus Muhumaal Pädaste mõisas, muusikaline estraadietendus "Tähtede sadu", Endla "Tsirkus!!!" Paikuse-Reiu vabaõhulaval (autor ja lavastaja Tiit Palu), Andrus Kivirähki näidend "Uljas Neitsi" Laulasmaa Resort' rannametsas (lavastaja Taavi Teplenkov), Marti Kivastik "Eesti asi" (lavastaja Ingomar Vihmar) MTÜ Ühendus R.A.A.A.M. Viinistu kunstimuuseumi vabaõhulaval, Emajõe Suveteatri suvelavastus "Jumalaema kiriku kellamees" Victor Hugo romaani järgi (lavastaja Andres Dvinjaninov), "Muna EÜE ehk Viimane kava" (autor Lauri Vahtre, lavastaja Andrus Vaarik) Suure Munamäe vabaõhulaval, Aino Kalda "Reigi õpetaja" Kuressaares (lavastaja ja dramatiseerija Aare Toikka), Vana Baskini Teateris Pierre Chesnot "Kes aevastas?" (lavastaja Eino Baskin), Eduard Vilde romaani "Prohvet Maltsvet" ja vene kirjaniku Viktor Pelevini romaani aineil sündinud lavastus "Proffet" Albu vallas Kukenoosi rehealuses (lavastaja Mart Koldits), Enn Vetemaa "Roosiaed" Raasiku vallas Kiviloo mõisas (lavastaja Eva Klemets), Jim Ashilevi "Portselansuits" (lavastaja Lauri Lagle) Eesti Teatriliidu saalis, Andres Keili "Rooside sõda" Leigo Järveteatris (lavastaja Tõnu Lensment), Võru Teatriateljee suvelavastus Madis Kõivu "Castrozza ehk illusionist" (lavastaja Taago Tubin), Villu Tamme "Haned võlgu" (lavastaja ja kunstnik Jaanika Juhanson) Teatrilabor Von Krahli teatris

  3. Eyelash Epilation in the Absence of Trichiasis: Results of a Population-Based Prevalence Survey in the Western Division of Fiji.

    Directory of Open Access Journals (Sweden)

    Colin Macleod

    2017-01-01

    Full Text Available The WHO definition of trachomatous trichiasis (TT is "at least one eyelash touching the globe, or evidence of recent epilation of in-turned eyelashes", reflecting the fact that epilation is used as a self-management tool for TT. In Fiji's Western Division, a high TT prevalence (8.7% in those aged ≥15 years was reported in a 2012 survey, yet a 2013 survey found no TT and Fijian ophthalmologists rarely see TT cases. Local anecdote suggests that eyelash epilation is a common behaviour, even in the absence of trichiasis. Epilators may have been identified as TT cases in previous surveys.We used a preliminary focus group to design an interview questionnaire, and subsequently conducted a population-based prevalence survey to estimate the prevalence of epilation in the absence of trichiasis, and factors associated with this behaviour, in the Western Division of Fiji.We sampled 695 individuals aged ≥15 years from a total of 457 households in 23 villages. 125 participants (18% reported epilating their eyelashes at least once within the past year. Photographs were obtained of the eyes of 121/125 (97% individuals who epilated, and subsequent analysis by an experienced trachoma grader found no cases of trachomatous conjunctival scarring or trichiasis. The age- and sex- adjusted prevalence of epilation in those aged ≥15 years was 8.6% (95% CI 5.7-11.3%. iTaukei ethnicity, female gender, and a higher frequency of drinking kava root were independently associated with epilation.Epilation occurs in this population in the absence of trichiasis, with sufficient frequency to have markedly inflated previous estimates of local TT prevalence. Individuals with epilated eyelashes should be confirmed as having epilated in-turned eyelashes in an eye with scarring of the conjunctiva before being counted as cases of TT.

  4. Occupational Stress and Burnout among Surgeons in Fiji.

    Science.gov (United States)

    Patel, Rajeev; Huggard, Peter; van Toledo, Annik

    2017-01-01

    This study examined the levels of occupational stress and burnout among surgeons in Fiji. A document set comprising a cover letter; a consent form; a sociodemographic and supplementary information questionnaire; the Maslach Burnout Inventory (MBI); the 12-item General Health Questionnaire (GHQ-12); the Alcohol Use Disorders Identification Test (AUDIT); and the Professional Quality of Life (ProQOL) questionnaires were provided to surgeons from three public divisional hospitals in Fiji. Thirty-six of 43 (83.7%) invited surgeons participated in the study. According to their MBI scores, surgeons suffered from low (10, 27.8%), moderate (23, 63.9%), and high (3, 8.3%) levels of burnout. Comparatively, 23 (63.9%) demonstrated moderate burnout according to their ProQOL scores. Substantial psychiatric morbidity was observed in 16 (44.0%) surgeons per their GHQ-12 scores. Consumption of alcohol was noted in 29 (80.6%) surgeons, and 12 (33.4%) had AUDIT scores characterizing their alcohol use in excess of low-risk guidelines or as harmful or hazardous drinking. Surgeons of Fijian nationality showed higher MBI emotional exhaustion and depersonalization scores compared with surgeons of other nationalities. Surgeons with an awareness of the availability of counseling services at their hospitals showed low AUDIT and ProQOL burnout scores. Smokers, alcohol drinkers, and kava drinkers showed higher AUDIT scores. This study highlights a level of occupational stress and burnout among surgeons in Fiji and a lack of awareness of their mental and physical well-being. The authors recommend that occupational stress and burnout intervention strategies be put in place in hospitals in Fiji.

  5. Rapid application design of an electronic clinical skills portfolio for undergraduate medical students.

    Science.gov (United States)

    Dornan, Tim; Lee, Catherine; Stopford, Adam; Hosie, Liam; Maredia, Neil; Rector, Alan

    2005-04-01

    The aim was to find how to use information and communication technology to present the clinical skills content of an undergraduate medical curriculum. Rapid application design was used to develop the product, and technical action research was used to evaluate the development process. A clinician-educator, two medical students, two computing science masters students, two other project workers, and a hospital education informatics lead, formed a design team. A sample of stakeholders took part in requirements planning workshops and continued to advise the team throughout the project. A university hospital had many features that favoured fast, inexpensive, and successful system development: a clearly defined and readily accessible user group; location of the development process close to end-users; fast, informal communication; leadership by highly motivated and senior end-users; devolved authority and lack of any rigidly imposed management structure; cooperation of clinicians because the project drew on their clinical expertise to achieve scholastic goals; a culture of learning and involvement of highly motivated students. A detailed specification was developed through storyboarding, use case diagramming, and evolutionary prototyping. A very usable working product was developed within weeks. "SkillsBase" is a database web application using Microsoft Active Server Pages, served from a Microsoft Windows 2000 Server operating system running Internet Information Server 5.0. Graphing functionality is provided by the KavaChart applet. It presents the skills curriculum, provides a password-protected portfolio function, and offers training materials. The curriculum can be presented in several different ways to help students reflect on their objectives and progress towards achieving them. The reflective portfolio function is entirely private to each student user and allows them to document their progress in attaining skills, as judged by self, peer and tutor assessment, and

  6. Nilai Rerata Vascular Pedicle Width, Vascular Pedicle-Cardiac Ratio Vascular Pedicle-Thoracic Ratio Orang Dewasa Normal Indonesia Studi di RS dr. Cipto Mangunkusomo

    Directory of Open Access Journals (Sweden)

    Rommy Zunera

    2016-03-01

    Full Text Available Vascular pedicle width (VPW adalah jarak tepi luar vena kava superior ke tepi luar arteri subklavia kiri. Pemeriksaan VPW di foto toraks bersifat non-invasif, cepat dan mudah untuk memprediksi hipervolemia.Penelitian ini bertujuan untuk mengetahui rerata nilai VPW orang dewasa normal Indonesia. VPW diukurdengan dua metode: pertama pengukuran VPW tunggal yang akurasinya terbatas di foto toraks digital karenarelatif tidak dipengaruhi faktor magnifikasi. Metode kedua untuk foto toraks nondigital yaitu pengukuranrasio:vascular pedicle-cardiac ratio (VPCR dan vascular pedicle-thoracic ratio (VPTR. Pengukuran serupadilakukan terhadap  topogram CT scan toraks AP terlentang dan CT scan toraks lalu dibandingkan akurasipengukuran di topogram dengan CT scan  toraks sebagai standar baku. Sampel terdiri atas 104 foto toraksPA subyek normal dan 103 CT scan  toraks subyek terpilih. Pada pemeriksaan toraks PA didapatkan rerata VPW 48,0±5,5mm, rerata VPCR 40,3±4,6%, dan rerata VPTR 17,2±1,7%. Pada pemeriksaan topogram CTscan didapatkan rerata VPW 50,3±6,2mm, rerata VPTR 45±5,1%, dan rerata VPTR 19,8±2,5%. Rerata VPWpada CT scan toraks 50,4±6,1mm. Pengukuran di foto toraks AP 10% lebih besar dibandingkan pada fototoraks PA dan pengukuranVPW di foto toraks terbukti memiliki akurasi  tinggi. Kata kunci: fototoraks, vascular pedicle width, vascular pedicle-cardiac ratio, vascular pedicle-thoracic ratio, hipervolemia.   The Mean Value of Vascular Pedicle Width, Vascular Pedicle-Cardiac Ratio,Vascular Pedicle-Thoracic Ratio of Normal Indonesian Adult Study In dr. Cipto Mangunkusomo Hospital Abstract Vascular pedicle width (VPW is the distance, from a perpendicular line at the takeoff point of the left subclavian artery off the aorta to the point at which the superior vena cava. Measurement of VPW on chestx-ray is relatively non-invasive, fast and easy technique as  hypervolemia predictor. The purpose of thisstudy is to know the mean VPW value of normal

  7. A NOON TIME IN YENISEHIR YENİŞEHİR’DE BİR ÖĞLE VAKTİ

    Directory of Open Access Journals (Sweden)

    Sefa YÜCE

    2010-04-01

    tilip kakılmaya devam eder. Evliliklerde, iki eşlilik yaygındır. Medeni kanun gerçek anlamda uygulanamaz. Toplumun bir kesimi gelenekle modernizm arasında sıkışır. Yazar, kavağı Ankara’da bir simge olarak seçer. Yaşlanan kavağın kimse farkında değildir. Mevhibe Hanım’ın bahçesindeki kavak ağacı, kapıcı Mevlüt’ün üzerine devrilir. Mevlüt ölür. Ankara’da kavağın devrilmesiyle birlikte köylülük de biter. Aynı zamanda kökleri kuruyan ve yaşama şansı olmayan kavak, kimliğini yitiren Ankara’nın simgesidir.Bu makalede uyum sürecinde yaşanan sorunlar ve yeni toplumsal yapı, metin-dilbilim anlayışı doğrultusunda yeni bir bakış açısıyla ele alınıp değerlendirilmeye çalışıldı.

  8. Herbal Treatment in Menopause

    Directory of Open Access Journals (Sweden)

    Cigdem Gun

    2015-12-01

    Full Text Available The digest has been prepared to review available clinical evidence on herbs used in treatment of menopause symptoms. Effectiveness of Humulus lupulus, Vitex agnus-castus, Dioskorea vilosa, Linum usitatissimum, Pinus pinaster, cruciferous vegetables, Cimicifuga racemosa L., Angelica sinensis, Oenothera biennis L., Hypericum perforatum L., Panax ginseng, Ginkgo biloba, Glycine soja, Trifolium pratense and Piper methysticum herbs were assessed for treatment of menopausal symptoms in the studies. Herbs used as alternative supplementary treatment for menopause symptoms have been found to have a limited effect. Thus more studies are warranted to assess effectiveness of herbal treatments for menopausal symptoms. [Archives Medical Review Journal 2015; 24(4.000: 520-530

  9. Gamma radiation (Co60) effects on active substances and microbe burden of medicinal plants

    International Nuclear Information System (INIS)

    Dall'Agnol, L.

    2001-01-01

    In order to evaluate the effects of radioactivity on active vegetal substances, samples of Fennel (Foeniculum vulgare Miller., fructus), Guarana (Paulinia cupana, Kunth, semen), Gingko (gingko biloba, L., folium), and Kawa-Kawa (Piper methysticum G. Forst, rhizoma), were treated with scaling doses (0 to 25 KGy) of gamma radiation (Co 60 ). The 'blind test' methodology was used. The active substances from each sample were analysed by qualitative and quantitative methods after radiation. There were no significant differences seen between the control sample (0 KGy) and the irradiated samples. Microbe contamination was significantly reduced, about 10000 CFU/g, with the initial 5 KGy dose. It was concluded that gamma radiation can be used as an alternative procedure to reduce microbiologic contamination in medicinal plants. Before this procedure can be extended to other medicinal plants, more specific analytical methods are recommended to verify possible structural alterations in active vegetal molecules. (author)

  10. Book Reviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV

    1992-01-01

    , 375 pp., Ceri Peach, Steven Vertovec (eds. - P. van Emst, Ron Brunton, The abandoned narcotic; Kava and cultural instability in Melanesia. Cambridge studies in social anthropology 69. Cambridge, etc.: Cambridge, University Press, 1989. - Th. van den End, Karel A. Steenbrink, De islam bekeken door koloniale Nederlanders. Utrecht/Leiden: Interuniversitair Instituut voor Missiologie en Oecumenica, 1991, 174 pp. - Th. van den End, Sutarman S. Partonadi, Sadrach’s community and its contextual roots; A nineteenth century Javanese expression of Christianity. Amsterdam-Atlanta: Rodopi, 1990, 317 pp. - Antonio J. Guerreiro, Bernard Sellato, Nomades et sedentarisation a Borneo; Histoire économique et sociale. Paris, Editions de l’Ecole des Hautes Etudes en Sciences Sociales, Etudes insulindiennes/Archipel 9, 1989, 293 p.; ill. - Jos G.M. Hilhorst, P.J.M. Nas, De sad in de Derde Wereld; Een inleiding tot de urbane antropologie en sociologie. Muiderberg: Coutinho, 1990; pp. 244. - S.R. Jaarsma, Stefan Dietrich, Kolonialismus und Mission auf Flores (ca. 1900-1942, Hohenschaftlarn: Klaus Renner Verlag (Münchner Beiträge zur Süd- und Südostasienkunde Band 1, 1989, vii + 347 pp. - M.C. Jongeling, Th. van den End, Ragi carita; Sejarah gereja di Indonesia I 1500-1860, 3rd impr. Jakarta 1987, - Roy.E. Jordaan, Michaela Appel, Dewi Sri und die Kinder des Putut Jantaka; Beziehungen zwischen Mensch und Reis in Mythologie und Brauchtum auf Java und Bali. München: Anacon Verlag, 1991. - S.C. Kersenboom, Joel C. Kuipers, Power in performance; The creation of textual authority in Weyewa ritual speech, 1990. Philadelphia, Pa: University of Pennysylvania press, conduct and communication series. - J. Kleinen, Marie Alexandre Martin, Le mal cambodgien; Histoire d’une societe traditionelle face a ses leaders politiques 1946-1987, Paris: Hachette, 1989. - G.J. Knaap, A. Booth, Indonesian economic history in the Dutch colonial era, Monograph series 35 Yale University Southeast Asia

  11. Testosterone 5alpha-reductase inhibitory active constituents of Piper nigrum leaf.

    Science.gov (United States)

    Hirata, Noriko; Tokunaga, Masashi; Naruto, Shunsuke; Iinuma, Munekazu; Matsuda, Hideaki

    2007-12-01

    Previously we reported that Piper nigrum leaf extract showed a potent stimulation effect on melanogenesis and that (-)-cubebin (1) and (-)-3,4-dimethoxy-3,4-desmethylenedioxycubebin (2) were isolated as active constituents. As a part of our continuous studies on Piper species for the development of cosmetic hair-care agents, testosterone 5alpha-reductase inhibitory activity of aqueous ethanolic extracts obtained from several different parts of six Piper species, namely Piper nigrum, P. methysticum, P. betle, P. kadsura, P. longum, and P. cubeba, were examined. Among them, the extracts of P. nigrum leaf, P. nigrum fruit and P. cubeba fruit showed potent inhibitory activity. Activity-guided fractionation of P. nigrum leaf extract led to the isolation of 1 and 2. Fruits of P. cubeba contain 1 as a major lignan, thus inhibitory activity of the fruit may be attributable to 1. As a result of further assay on other known constituents of the cited Piper species, it was found that piperine, a major alkaloid amide of P. nigrum fruit, showed potent inhibitory activity, thus a part of the inhibitory activity of P. nigrum fruit may depend on piperine. The 5alpha-reductase inhibitory activities of 1 and piperine were found for the first time. In addition, the P. nigrum leaf extract showed in vivo anti-androgenic activity using the hair regrowth assay in testosterone sensitive male C57Black/6CrSlc strain mice.

  12. Herbal Highs: Review on Psychoactive Effects and Neuropharmacology.

    Science.gov (United States)

    Graziano, Silvia; Orsolini, Laura; Rotolo, Maria Concetta; Tittarelli, Roberta; Schifano, Fabrizio; Pichini, Simona

    2017-01-01

    A new trend among users of new psychoactive substances' the consumption of "herbal highs": plant parts containing psychoactive substances. Most of the substances extracted from herbs, in old centuries were at the centre of religious ceremonies of ancient civilizations. Currently, these herbal products are mainly sold by internet web sites and easily obtained since some of them have no legal restriction. We reviewed psychoactive effects and neuropharmacology of the most used "herbal highs" with characterized active principles, with studies reporting mechanisms of action, pharmacological and subjective effects, eventual secondary effects including intoxications and/or fatalities Method: The PubMed database was searched using the following key.words: herbal highs, Argyreia nervosa, Ipomoea violacea and Rivea corymbosa; Catha edulis; Datura stramonium; Piper methysticum; Mitragyna speciosa. Psychoactive plants here reviewed have been known and used from ancient times, even if for some of them limited information still exist regarding subjective and neuropharmacological effects and consequent eventual toxicity when plants are used alone or in combination with "classical" drugs of abuse. Some "herbal highs" should be classified as harmful drugs since chronic administration has been linked with addiction and cognitive impairment; for some others taking into consideration only the recent trends of abuse, studies investigating these aspects are lacking. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  13. Herbal medicine for depression, anxiety and insomnia: a review of psychopharmacology and clinical evidence.

    Science.gov (United States)

    Sarris, Jerome; Panossian, Alexander; Schweitzer, Isaac; Stough, Con; Scholey, Andrew

    2011-12-01

    Research in the area of herbal psychopharmacology has increased markedly over the past decades. To date however, a comprehensive review of herbal antidepressant, anxiolytic and hypnotic psychopharmacology and applications in depression, anxiety and insomnia has been absent. A search of MEDLINE (PubMed), CINAHL, PsycINFO, and the Cochrane Library databases was conducted (up to February 21st 2011) on commonly used psychotropic herbal medicines. A review of the literature was conducted to ascertain mechanisms of action of these botanicals, in addition to a systematic review of controlled clinical trials for treatment of mood, anxiety and sleep disorders, which are common comorbid psychiatric disorders. Specific emphasis was given to emerging phytomedicines. Analysis of evidence levels was conducted, as were effect sizes (Cohen's d) where data were available. Results provided evidence of a range of neurochemical, endocrinological, and epigenetic effects for 21 individual phytomedicines, which are detailed in this paper. Sixty six controlled studies were located involving eleven phytomedicines. Several of these provide a high level of evidence, such as Hypericum perforatum for major depression, and Piper methysticum for anxiety disorders. Several human clinical trials provide preliminary positive evidence of antidepressant effects (Echium amoenum, Crocus sativus, and Rhodiola rosea) and anxiolytic activity (Matricaria recutita, Ginkgo biloba, Passiflora incanata, E. amoenum, and Scutellaria lateriflora). Caution should however be taken when interpreting the results as many studies have not been replicated. Several herbal medicines with in vitro and in vivo evidence are currently unexplored in human studies, and along with use of emerging genetic technologies "herbomics", are areas of potential future research. Copyright © 2011 Elsevier B.V. All rights reserved.

  14. Design, Synthesis and Docking Studies of Flavokawain B Type Chalcones and Their Cytotoxic Effects on MCF-7 and MDA-MB-231 Cell Lines

    Directory of Open Access Journals (Sweden)

    Addila Abu Bakar

    2018-03-01

    Full Text Available Flavokawain B (1 is a natural chalcone extracted from the roots of Piper methysticum, and has been proven to be a potential cytotoxic compound. Using the partial structure of flavokawain B (FKB, about 23 analogs have been synthesized. Among them, compounds 8, 13 and 23 were found in new FKB derivatives. All compounds were evaluated for their cytotoxic properties against two breast cancer cell lines, MCF-7 and MDA-MB-231, thus establishing the structure–activity relationship. The FKB derivatives 16 (IC50 = 6.50 ± 0.40 and 4.12 ± 0.20 μg/mL, 15 (IC50 = 5.50 ± 0.35 and 6.50 ± 1.40 μg/mL and 13 (IC50 = 7.12 ± 0.80 and 4.04 ± 0.30 μg/mL exhibited potential cytotoxic effects on the MCF-7 and MDA-MB-231 cell lines. However, the methoxy group substituted in position three and four in compound 2 (IC50 = 8.90 ± 0.60 and 6.80 ± 0.35 μg/mL and 22 (IC50 = 8.80 ± 0.35 and 14.16 ± 1.10 μg/mL exhibited good cytotoxicity. The lead compound FKB (1 showed potential cytotoxicity (IC50 = 7.70 ± 0.30 and 5.90 ± 0.30 μg/mL against two proposed breast cancer cell lines. It is evident that the FKB skeleton is unique for anticancer agents, additionally, the presence of halogens (Cl and F in position 2 and 3 also improved the cytotoxicity in FKB series. These findings could help to improve the future drug discovery process to treat breast cancer. A molecular dynamics study of active compounds revealed stable interactions within the active site of Janus kinase. The structures of all compounds were determined by 1H-NMR, EI-MS, IR and UV and X-ray crystallographic spectroscopy techniques.

  15. Journal Abstracts

    Directory of Open Access Journals (Sweden)

    Mete Korkut Gülmen

    1996-07-01

    çesinden oluşturuldu ve aynı kişilerin kan örneklerinin sekanslarıyla karşılaştırıldı. Kan ve feçes örneklerinde sekanslar özdeşti fakat sekans değişkenleri yaklaşık her 400bp'de 4.88 olan bir ortalama ile, 1-10 sınırlarında bireyler arasında nükleotid farklılıkları gözlendi. Bu çalışmada uygulanan çeşitli ekstraksiyon protokolleri arasında DNA'yı bağlama ve saflaştırma işleminde en yüksek oranda başarıya manyetik partikül seperasyonuna dayanan organik ekstraksiyon yöntemiyle ulaşıldı. Feçesten DNA ekstraksiyonunda STR analizi rutin olarak olası değildi. İLAÇLARIN MİDEDEKİ ARTIKLARDAN POSTMORTEM DİFÜZYONU Postmortem diffusion of drugs from gastric residue, an experimental study Pounder DJ, Fuke C, Cox DE, Smith D, Kuroda N. Am J Forensic Med-Pathol. 1996; 17(1: 1-7. İlaçların midedeki artıklardan postmortem difüzyonu bir insan kadavrası modeli üzerinde çalışılmıştır. 350 mİ % 10’luk metanol ve 0.1 N HC1 içinde elli miligram amit- riptilin (Ami ve 5 gram parasetamol (Par süspansiyonu ve 50 gram ürografin 5 gram lityum karbonat (alkali model ile ve lityum karbonatsız (asidik model olarak boyun diseksiyonu ile bir özofagus tübü yoluyla mide içine konulmuştur. Oda sıcaklığında (Ortalama saatlik oda sıcaklığı sınırları: 15.6-20.70C, n = 9 geçen 48 saatten sonra bir çok örnek alınmıştır. Mide içeriğinin pH’ının anlamlı ( alkalin model sınırlar = 8.3-8.9, n = 5, asidik model sınırları = 3.4-3-8, n = 5 bir etkisi olmamıştır. İlaç difüzyonu Ami için 0.1-13-9 (pg/g, Par için 65- 524, ve lityum için 13-161 konsantrasyonlarında en çok sol akciğer tabanında belirgindi. Benzer şekilde karaciğer sol lobunda (Ami, 0.1-54.9; Par, 7-218; lityum 7-39, dalakta (Ami, 0.6-24.3; Par, 104-663; lityum, 27-106, ve perikard sıvısında (Ami, 0-4.5; Par, 48-641; lityum, 12- 56 belirgin konsantrasyonlar bulundu. Safra kesesine, kalp kanına, aorta kanına ve inferior vena kava