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Sample records for methods show considerable

  1. Survey Shows Variation in Ph.D. Methods Training.

    Science.gov (United States)

    Steeves, Leslie; And Others

    1983-01-01

    Reports on a 1982 survey of journalism graduate studies indicating considerable variation in research methods requirements and emphases in 23 universities offering doctoral degrees in mass communication. (HOD)

  2. Temperament: a consideration of concepts and methods.

    Science.gov (United States)

    Stevenson, J; Graham, P

    1982-01-01

    This paper discusses conceptual issues and begins with a consideration of definitions of temperament. It is suggested that the purposes for which temperament has been studied have, to some degree, dictated methods used and inferences drawn. Those psychopathologists interested in the relationship between temperament and psychiatric disorder, or emotional and behavioural disturbance, have tended to use different methods from those more concerned with delineating the structure of personality. Some issues and problems are common to both approaches, e.g. the definition of behaviour reflecting temperament in terms of style rather than content. Other issues, such as the difficulty involved in drawing a clear distinction between temperamental attributes and mental disorders, are restricted to one approach. The relative contribution of gentic and environmental effects is of interest to both psychopathologists (who wish to examine this issue in relation to the development of the individual), and to psychologists (who are usually more concerned with populations or aggregate effects). The application of biometric genetic models might clarify this issue, and various suggestions are made regarding steps that need to be taken if such models are to be successfully applied.

  3. Brief considerations on business valuation methods

    Directory of Open Access Journals (Sweden)

    Julio César Riascos Hermoza

    2017-11-01

    Full Text Available Nowadays, determining the value of a business has gained significant importance in academic and business fields, as the understanding of the value of an organization has become a key tool for the management and marketing of a business. Accordingly, numerous methods have been developed in order to perform these kinds of practices. In this article, the most used and current methods in processes of business evaluation are revised, observing their strengths and weaknesses, with the aim of comparing them and determining that the discounted cash flow methods are the most adequate procedures to perform this type of analysis.

  4. Survivors of cardiac arrest with good neurological outcome show considerable impairments of memory functioning.

    Science.gov (United States)

    Sulzgruber, Patrick; Kliegel, Andreas; Wandaller, Cosima; Uray, Thomas; Losert, Heidrun; Laggner, Anton N; Sterz, Fritz; Kliegel, Matthias

    2015-03-01

    Deficits in cognitive function are a well-known dysfunction in survivors of cardiac arrest. However, data concerning memory function in this neurological vulnerable patient collective remain scarce and inconclusive. Therefore, we aimed to assess multiple aspects of retrospective and prospective memory performance in patients after cardiac arrest. We prospectively enrolled 33 survivors of cardiac arrest, with cerebral performance categories (CPC) 1 and 2 and a control-group (n=33) matched in sex, age and educational-level. To assess retrospective and prospective memory performance we administrated 4 weeks after cardiac arrest the "Rey Adult Learning Test" (RAVLT), the "Digit-Span-Backwards Test", the "Logic-Memory Test" and the "Red-Pencil Test". Results indicate an impairment in immediate and delayed free recall, but not in recognition. However, the overall impairment in immediate recall was qualified by analyzing RAVLT performance, showing that patients were only impaired in trials 4 and 5 of the learning sequence. Moreover, working and prospective memory as well as prose recall were worse in cardiac arrest survivors. Cranial computed tomography was available in 61% of all patients (n=20) but there was no specific neurological damage detectable that could be linked to this cognitive impairment. Episodic long-term memory functioning appears to be particularly impaired after cardiac arrest. In contrast, short-term memory storage, even tested via free-call, seems not to be affected. Based on cranial computed tomography we suggest that global brain ischemia rather than focal brain lesions appear to underlie these effects. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  5. Bioanalytical method transfer considerations of chromatographic-based assays.

    Science.gov (United States)

    Williard, Clark V

    2016-07-01

    Bioanalysis is an important part of the modern drug development process. The business practice of outsourcing and transferring bioanalytical methods from laboratory to laboratory has increasingly become a crucial strategy for successful and efficient delivery of therapies to the market. This chapter discusses important considerations when transferring various types of chromatographic-based assays in today's pharmaceutical research and development environment.

  6. How the Television Show "Mythbusters" Communicates the Scientific Method

    Science.gov (United States)

    Zavrel, Erik; Sharpsteen, Eric

    2016-01-01

    The importance of understanding and internalizing the scientific method can hardly be exaggerated. Unfortunately, it is all too common for high school--and even university--students to graduate with only a partial or oversimplified understanding of what the scientific method is and how to actually employ it. Help in remedying this situation may…

  7. VAN method of short-term earthquake prediction shows promise

    Science.gov (United States)

    Uyeda, Seiya

    Although optimism prevailed in the 1970s, the present consensus on earthquake prediction appears to be quite pessimistic. However, short-term prediction based on geoelectric potential monitoring has stood the test of time in Greece for more than a decade [VarotsosandKulhanek, 1993] Lighthill, 1996]. The method used is called the VAN method.The geoelectric potential changes constantly due to causes such as magnetotelluric effects, lightning, rainfall, leakage from manmade sources, and electrochemical instabilities of electrodes. All of this noise must be eliminated before preseismic signals are identified, if they exist at all. The VAN group apparently accomplished this task for the first time. They installed multiple short (100-200m) dipoles with different lengths in both north-south and east-west directions and long (1-10 km) dipoles in appropriate orientations at their stations (one of their mega-stations, Ioannina, for example, now has 137 dipoles in operation) and found that practically all of the noise could be eliminated by applying a set of criteria to the data.

  8. Method for depth referencing hydrocarbon gas shows on mud logs

    International Nuclear Information System (INIS)

    Dion, E.P.

    1986-01-01

    A method is described for identifying hydrocarbon formations surrounding a borehole, comprising the steps of: a. measuring hydrocarbon gas in the entrained formation cuttings obtained during drilling operations in which a drilling mud is continually circulated past a drill bit to carry the cuttings to the earth's surface, b. simultaneously measuring natural gamma radiation in the cuttings, c. identifying the depths at which the cuttings were obtained within the borehole, d. measuring natural gamma radiation within the borehole following completion of the drilling operations, e. correlating the natural gamma radiation measurements in steps (b) and (d), and f. identifying the depths within the borehole from which the entrained cuttings containing hydrocarbon gas were obtained during drilling operations when there is correlation between the natural gamma radiation measurements in steps (b) and (d)

  9. Testosterone Responders to Continuous Androgen Deprivation Therapy Show Considerable Variations in Testosterone Levels on Followup: Implications for Clinical Practice.

    Science.gov (United States)

    Sayyid, Rashid K; Sayyid, Abdallah K; Klaassen, Zachary; Fadaak, Kamel; Goldberg, Hanan; Chandrasekar, Thenappan; Ahmad, Ardalanejaz; Leao, Ricardo; Perlis, Nathan; Chadwick, Karen; Hamilton, Robert J; Kulkarni, Girish S; Finelli, Antonio; Zlotta, Alexandre R; Fleshner, Neil E

    2018-01-01

    We determined whether men on continuous androgen deprivation therapy who achieve testosterone less than 0.7 nmol/l demonstrate subsequent testosterone elevations during followup and whether such events predict worse oncologic outcomes. We evaluated a random, retrospective sample of 514 patients with prostate cancer treated with continuous androgen deprivation therapy in whom serum testosterone was less than 0.7 nmol/l at University Health Network between 2007 and 2016. Patients were followed from the date of the first testosterone measurement of less than 0.7 nmol/l to progression to castrate resistance, death or study period end. Study outcomes were the development of testosterone elevations greater than 0.7, greater than 1.1 and greater than 1.7 nmol/l, and progression to a castrate resistant state. Survival curves were constructed to determine the rate of testosterone elevations. Multivariate Cox regression analysis was done to assess whether elevations predicted progression to castrate resistance. Median patient age was 74 years and median followup was 20.3 months. Within 5 years of followup 82%, 45% and 18% of patients had subsequent testosterone levels greater than 0.7, greater than 1.1 and greater than 1.7 nmol/l, respectively. In 96% to 100% of these patients levels less than 0.7 nmol/l were subsequently reestablished within 5 years. No patient baseline characteristic was associated with elevations and elevations were not a significant predictor of progression to a castrate resistant state. Men on continuous androgen deprivation therapy in whom initial testosterone is less than 0.7 nmol/l frequently show subsequent elevations in serum testosterone. Such a development should not trigger an immediate response from physicians as these events are prognostically insignificant with regard to oncologic outcomes. Levels are eventually reestablished at less than 0.7 nmol/l. Copyright © 2018 American Urological Association Education and Research, Inc. Published by

  10. DEPEND-HRA-A method for consideration of dependency in human reliability analysis

    International Nuclear Information System (INIS)

    Cepin, Marko

    2008-01-01

    A consideration of dependencies between human actions is an important issue within the human reliability analysis. A method was developed, which integrates the features of existing methods and the experience from a full scope plant simulator. The method is used on real plant-specific human reliability analysis as a part of the probabilistic safety assessment of a nuclear power plant. The method distinguishes dependency for pre-initiator events from dependency for initiator and post-initiator events. The method identifies dependencies based on scenarios, where consecutive human actions are modeled, and based on a list of minimal cut sets, which is obtained by running the minimal cut set analysis considering high values of human error probabilities in the evaluation. A large example study, which consisted of a large number of human failure events, demonstrated the applicability of the method. Comparative analyses that were performed show that both selection of dependency method and selection of dependency levels within the method largely impact the results of probabilistic safety assessment. If the core damage frequency is not impacted much, the listings of important basic events in terms of risk increase and risk decrease factors may change considerably. More efforts are needed on the subject, which will prepare the background for more detailed guidelines, which will remove the subjectivity from the evaluations as much as it is possible

  11. Unplanned Complex Suicide-A Consideration of Multiple Methods.

    Science.gov (United States)

    Ateriya, Navneet; Kanchan, Tanuj; Shekhawat, Raghvendra Singh; Setia, Puneet; Saraf, Ashish

    2018-05-01

    Detailed death investigations are mandatory to find out the exact cause and manner in non-natural deaths. In this reference, use of multiple methods in suicide poses a challenge for the investigators especially when the choice of methods to cause death is unplanned. There is an increased likelihood that doubts of homicide are raised in cases of unplanned complex suicides. A case of complex suicide is reported where the victim resorted to multiple methods to end his life, and what appeared to be an unplanned variant based on the death scene investigations. A meticulous crime scene examination, interviews of the victim's relatives and other witnesses, and a thorough autopsy are warranted to conclude on the cause and manner of death in all such cases. © 2017 American Academy of Forensic Sciences.

  12. Considerations and Methods for Usability Testing with Children

    DEFF Research Database (Denmark)

    Andersen, Malene Hjortboe; Khalid, Md. Saifuddin; Brooks, Eva Irene

    2017-01-01

    of these methods is that they are designed for adults and are not necessarily appropriate to investigations including children. The guiding questions for this systematic literature review are (1) the motivation for conducting usability tests with children, and (2) the kind of methodological, practical, and ethical...

  13. Noninvasive methods to measure airway inflammation: future considerations

    NARCIS (Netherlands)

    Magnussen, H.; Holz, O.; Sterk, P. J.; Hargreave, F. E.

    2000-01-01

    This last contribution to the series focuses on open questions regarding: 1) methodological issues; and 2) the potential clinical application of the noninvasive methods such as induced sputum and the analysis of exhaled air for the assessment of airway inflammation. In addition their potential

  14. What is the proper evaluation method: Some basic considerations

    International Nuclear Information System (INIS)

    Leeb, Helmut; Schnabel, Georg; Srdinko, Thomas

    2014-01-01

    Recent developments and applications demand for an extension of the energy range and the inclusion of reliable uncertainty information in nuclear data libraries. Due to the scarcity of neutron-induced reaction data beyond 20 MeV the extension of the energy range up to at least 150 MeV is not trivial because the corresponding nuclear data evaluations depend heavily on nuclear models and proper evaluation methods are still under discussion. Restricting to evaluation techniques based on Bayesian statistics the influence of the a priori knowledge on the final result of the evaluation is considered. The study clearly indicates the need to account properly for the deficiencies of the nuclear model. Concerning the covariance matrices it is argued that they depend not only on the model, but also on the method of generation and an additional consent is required for the comparison of different evaluations of the same data sets. (authors)

  15. Particle fluxes above forests: Observations, methodological considerations and method comparisons

    International Nuclear Information System (INIS)

    Pryor, S.C.; Larsen, S.E.; Sorensen, L.L.; Barthelmie, R.J.

    2008-01-01

    This paper reports a study designed to test, evaluate and compare micro-meteorological methods for determining the particle number flux above forest canopies. Half-hour average particle number fluxes above a representative broad-leaved forest in Denmark derived using eddy covariance range from -7 x 10 7 m -2 s -1 (1st percentile) to 5 x 10 7 m -2 s -1 (99th percentile), and have a median value of -1.6 x 10 6 m -2 s -1 . The statistical uncertainties associated with the particle number flux estimates are larger than those for momentum fluxes and imply that in this data set approximately half of the particle number fluxes are not statistically different to zero. Particle number fluxes from relaxed eddy accumulation (REA) and eddy covariance are highly correlated and of almost identical magnitude. Flux estimates from the co-spectral and dissipation methods are also correlated with those from eddy covariance but exhibit higher absolute magnitude of fluxes. - Number fluxes of ultra-fine particles over a forest computed using four micro-meteorological techniques are highly correlated but vary in magnitude

  16. Considerations on the question of applying ion exchange or reverse osmosis methods in boiler feedwater processing

    International Nuclear Information System (INIS)

    Marquardt, K.; Dengler, H.

    1976-01-01

    This consideration is to show that the method of reverse osmosis presents in many cases an interesting and economical alternative to part and total desolination plants using ion exchangers. The essential advantages of the reverse osmosis are a higher degree of automization, no additional salting of the removed waste water, small constructional volume of the plant as well as favourable operational costs with increasing salt content of the crude water to be processed. As there is a relatively high salt breakthrough compared to the ion exchange method, the future tendency in boiler feedwater processing will be more towards a combination of methods of reverse osmosis and post-purification through continuous ion exchange methods. (orig./LH) [de

  17. METHODOLOGICAL ASPECTS OF ECONOMIC EVENTS CYCLICITY METHOD CONSIDERATION

    Directory of Open Access Journals (Sweden)

    Yaskova Natalia Yur'ievna

    2017-07-01

    Full Text Available The cyclicity of economic phenomena is not only their immanent property but also the subject of economic analysis. The modern way of making managerial decisions requires analysis of a number of cycles that fill any kind of activity. Accounting and reconciliation of construction, design, investment, purchasing, reproduction, leasing and other cycles is important for the investment and construction sector, both from the point of view of the need for their synchronization and from the position of determining trends in sectoral development. The analysis has showed that three main types of development are characteristic for investment and construction activity. Increasing intensity is inherent in a high level of cyclic synchronization. The degradation trend arises as a result of mismatched cycles. The stabilization character is inherent in the regular modes of maintaining the established proportions and cyclical inter-conformity. The study of the cyclical nature of investment and building processes is impossible without understanding their co-ordination. The principles of synchronization and subordination of the cycles should be used not only for the construction of cost-effective systems but also for the development of management tools.

  18. New method for rearing Spodoptera frugiperda in laboratory shows that larval cannibalism is not obligatory

    Directory of Open Access Journals (Sweden)

    Cherre Sade Bezerra Da Silva

    2013-09-01

    Full Text Available New method for rearing Spodoptera frugiperda in laboratory shows that larval cannibalism is not obligatory. Here we show, for the first time, that larvae of the fall armyworm (FAW, Spodoptera frugiperda (Lepidoptera, Noctuidae, can be successfully reared in a cohort-based manner with virtually no cannibalism. FAW larvae were reared since the second instar to pupation in rectangular plastic containers containing 40 individuals with a surprisingly ca. 90% larval survivorship. Adult females from the cohort-based method showed fecundity similar to that already reported on literature for larvae reared individually, and fertility higher than 99%, with the advantage of combining economy of time, space and material resources. These findings suggest that the factors affecting cannibalism of FAW larvae in laboratory rearings need to be reevaluated, whilst the new technique also show potential to increase the efficiency of both small and mass FAW rearings.

  19. A simple identification method for spore-forming bacteria showing high resistance against γ-rays

    International Nuclear Information System (INIS)

    Koshikawa, Tomihiko; Sone, Koji; Kobayashi, Toshikazu

    1993-01-01

    A simple identification method was developed for spore-forming bacteria which are highly resistant against γ-rays. Among 23 species of Bacillus studied, the spores of Bacillus megaterium, B. cereus, B. thuringiensis, B. pumilus and B. aneurinolyticus showed high resistance against γ-rays as compared with other spores of Bacillus species. Combination of the seven kinds of biochemical tests, namely, the citrate utilization test, nitrate reduction test, starch hydrolysis test, Voges-Proskauer reaction test, gelatine hydrolysis test, mannitol utilization test and xylose utilization test showed a characteristic pattern for each species of Bacillus. The combination pattern of each the above tests with a few supplementary test, if necessary, was useful to identify Bacillus species showing high radiation resistance against γ-rays. The method is specific for B. megaterium, B. thuringiensis and B. pumilus, and highly selective for B. aneurinolyticus and B. cereus. (author)

  20. Critical considerations for the application of environmental DNA methods to detect aquatic species

    Science.gov (United States)

    Goldberg, Caren S.; Turner, Cameron R.; Deiner, Kristy; Klymus, Katy E.; Thomsen, Philip Francis; Murphy, Melanie A.; Spear, Stephen F.; McKee, Anna; Oyler-McCance, Sara J.; Cornman, Robert S.; Laramie, Matthew B.; Mahon, Andrew R.; Lance, Richard F.; Pilliod, David S.; Strickler, Katherine M.; Waits, Lisette P.; Fremier, Alexander K.; Takahara, Teruhiko; Herder, Jelger E.; Taberlet, Pierre

    2016-01-01

    Species detection using environmental DNA (eDNA) has tremendous potential for contributing to the understanding of the ecology and conservation of aquatic species. Detecting species using eDNA methods, rather than directly sampling the organisms, can reduce impacts on sensitive species and increase the power of field surveys for rare and elusive species. The sensitivity of eDNA methods, however, requires a heightened awareness and attention to quality assurance and quality control protocols. Additionally, the interpretation of eDNA data demands careful consideration of multiple factors. As eDNA methods have grown in application, diverse approaches have been implemented to address these issues. With interest in eDNA continuing to expand, supportive guidelines for undertaking eDNA studies are greatly needed.Environmental DNA researchers from around the world have collaborated to produce this set of guidelines and considerations for implementing eDNA methods to detect aquatic macroorganisms.Critical considerations for study design include preventing contamination in the field and the laboratory, choosing appropriate sample analysis methods, validating assays, testing for sample inhibition and following minimum reporting guidelines. Critical considerations for inference include temporal and spatial processes, limits of correlation of eDNA with abundance, uncertainty of positive and negative results, and potential sources of allochthonous DNA.We present a synthesis of knowledge at this stage for application of this new and powerful detection method.

  1. Different methods to quantify Listeria monocytogenesbiofilms cells showed different profile in their viability

    Directory of Open Access Journals (Sweden)

    Lizziane Kretli Winkelströter

    2015-03-01

    Full Text Available Listeria monocytogenes is a foodborne pathogen able to adhere and to form biofilms in several materials commonly present in food processing plants. The aim of this study was to evaluate the resistance of Listeria monocytogenes attached to abiotic surface, after treatment with sanitizers, by culture method, microscopy and Quantitative Real Time Polymerase Chain Reaction (qPCR. Biofilms of L. monocytogenes were obtained in stainless steel coupons immersed in Brain Heart Infusion Broth, under agitation at 37 °C for 24 h. The methods selected for this study were based on plate count, microscopic count with the aid of viability dyes (CTC-DAPI, and qPCR. Results of culture method showed that peroxyacetic acid was efficient to kill sessile L. monocytogenes populations, while sodium hypochlorite was only partially effective to kill attached L. monocytogenes (p < 0.05. When, viability dyes (CTC/DAPI combined with fluorescence microscopy and qPCR were used and lower counts were found after treatments (p < 0.05. Selective quantification of viable cells of L. monocytogenes by qPCR using EMA revelead that the pre-treatment with EMA was not appropriate since it also inhibited amplification of DNA from live cells by ca. 2 log. Thus, the use of CTC counts was the best method to count viable cells in biofilms.

  2. Consideration of Wall Reflection and Diffraction in the Room Acoustic Prediction Using the Phased Beam Tracing Method

    DEFF Research Database (Denmark)

    Jeong, Cheol-Ho

    2007-01-01

    of the applicability of the geometrical methods to mid frequency. Several studies on this method have demonstrated a good possibility to analyze the sound field in an enclosure at mid frequency. In this study, further considerations on wall reflection and diffraction have been investigated. The main suggestions...... of representing the negative real part was discussed. The PBTM result shows a good agreement with the measurement especially in the early part of impulse response and at mid frequency. The new method of ii binaural simulation for the PBTM was suggested. The peculiar feature of frequency domain calculation......The geometrical acoustics methods have been used to simulate the acoustics of rooms at high frequencies whereas the wave based methods have been devoted to calculate the low frequency response. The modified method, so called phased geometrical acoustics technique, was suggested for the extension...

  3. Developing and validating a nutrition knowledge questionnaire: key methods and considerations.

    Science.gov (United States)

    Trakman, Gina Louise; Forsyth, Adrienne; Hoye, Russell; Belski, Regina

    2017-10-01

    To outline key statistical considerations and detailed methodologies for the development and evaluation of a valid and reliable nutrition knowledge questionnaire. Literature on questionnaire development in a range of fields was reviewed and a set of evidence-based guidelines specific to the creation of a nutrition knowledge questionnaire have been developed. The recommendations describe key qualitative methods and statistical considerations, and include relevant examples from previous papers and existing nutrition knowledge questionnaires. Where details have been omitted for the sake of brevity, the reader has been directed to suitable references. We recommend an eight-step methodology for nutrition knowledge questionnaire development as follows: (i) definition of the construct and development of a test plan; (ii) generation of the item pool; (iii) choice of the scoring system and response format; (iv) assessment of content validity; (v) assessment of face validity; (vi) purification of the scale using item analysis, including item characteristics, difficulty and discrimination; (vii) evaluation of the scale including its factor structure and internal reliability, or Rasch analysis, including assessment of dimensionality and internal reliability; and (viii) gathering of data to re-examine the questionnaire's properties, assess temporal stability and confirm construct validity. Several of these methods have previously been overlooked. The measurement of nutrition knowledge is an important consideration for individuals working in the nutrition field. Improved methods in the development of nutrition knowledge questionnaires, such as the use of factor analysis or Rasch analysis, will enable more confidence in reported measures of nutrition knowledge.

  4. Comparing personal insight gains due to consideration of a recent dream and consideration of a recent event using the Ullman and Schredl dream group methods.

    Science.gov (United States)

    Edwards, Christopher L; Malinowski, Josie E; McGee, Shauna L; Bennett, Paul D; Ruby, Perrine M; Blagrove, Mark T

    2015-01-01

    There have been reports and claims in the psychotherapeutic literature that the consideration of recent dreams can result in personal realizations and insight. There is theoretical support for these claims from work on rapid eye movement (REM) sleep having a function of the consolidation of emotional memories and the creative formation of connections between new and older memories. To investigate these claims, 11 participants (10 females, one male) reported and considered a recent home dream in a dream discussion group that following the "Appreciating dreams" method of Montague Ullman. The group ran 11 times, each participant attending and participating once. A further nine participants (seven females, two males) reported and considered a recent home dream in a group that followed the "Listening to the dreamer" method of Michael Schredl. The two studies each had a control condition where the participant also reported a recent event, the consideration of which followed the same technique as was followed for the dream report. Outcomes of the discussions were assessed by the participants on the Gains from Dream Interpretation (GDI) scale, and on its counterpart, the Gains from Event Interpretation scale. High ratings on the GDI experiential-insight subscale were reported for both methods, when applied to dreams, and for the Ullman method Exploration-Insight ratings for the dream condition were significantly higher than for the control event condition. In the Ullman method, self-assessment of personal insight due to consideration of dream content was also significantly higher than for the event consideration condition. The findings support the view that benefits can be obtained from the consideration of dream content, in terms of identifying the waking life sources of dream content, and because personal insight may also occur. To investigate the mechanisms for the findings, the studies should be repeated with REM and non-REM dream reports, hypothesizing greater insight

  5. Comparing personal insight gains due to consideration of a recent dream and consideration of a recent event using the Ullman and Schredl dream group methods

    Directory of Open Access Journals (Sweden)

    Christopher Lloyd Edwards

    2015-06-01

    Full Text Available There have been reports and claims in the psychotherapeutic literature that the consideration of recent dreams can result in personal realizations and insight. There is theoretical support for these claims from work on Rapid Eye Movement sleep having a function of the consolidation of emotional memories and the creative formation of connections between new and older memories. To investigate these claims, 11 participants (10 females, 1 male reported and considered a recent home dream in a dream discussion group that following the ‘Appreciating dreams’ method of Montague Ullman. The group ran 11 times, each participant attending and participating once. A further nine participants (7 females, 2 males reported and considered a recent home dream in a group that followed the ‘Listening to the dreamer’ method of Michael Schredl. The two studies each had a control condition where the participant also reported a recent event, the consideration of which followed the same technique as was followed for the dream report. Outcomes of the discussions were assessed by the participants on the Gains from Dream Interpretation scale, and on its counterpart, the Gains from Event Interpretation scale. High ratings on the GDI experiential-insight subscale were reported for both methods, when applied to dreams, and for the Ullman method exploration-insight ratings for the dream condition were significantly higher than for the control event condition. In the Ullman method, self-assessment of personal insight due to consideration of dream content was also significantly higher than for the event consideration condition. The findings support the view that benefits can be obtained from the consideration of dream content, in terms of identifying the waking life sources of dream content, and because personal insight may also occur. To investigate the mechanisms for the findings, the studies should be repeated with REM and NREM dream reports, hypothesizing greater

  6. Comparing personal insight gains due to consideration of a recent dream and consideration of a recent event using the Ullman and Schredl dream group methods

    Science.gov (United States)

    Edwards, Christopher L.; Malinowski, Josie E.; McGee, Shauna L.; Bennett, Paul D.; Ruby, Perrine M.; Blagrove, Mark T.

    2015-01-01

    There have been reports and claims in the psychotherapeutic literature that the consideration of recent dreams can result in personal realizations and insight. There is theoretical support for these claims from work on rapid eye movement (REM) sleep having a function of the consolidation of emotional memories and the creative formation of connections between new and older memories. To investigate these claims, 11 participants (10 females, one male) reported and considered a recent home dream in a dream discussion group that following the “Appreciating dreams” method of Montague Ullman. The group ran 11 times, each participant attending and participating once. A further nine participants (seven females, two males) reported and considered a recent home dream in a group that followed the “Listening to the dreamer” method of Michael Schredl. The two studies each had a control condition where the participant also reported a recent event, the consideration of which followed the same technique as was followed for the dream report. Outcomes of the discussions were assessed by the participants on the Gains from Dream Interpretation (GDI) scale, and on its counterpart, the Gains from Event Interpretation scale. High ratings on the GDI experiential-insight subscale were reported for both methods, when applied to dreams, and for the Ullman method Exploration-Insight ratings for the dream condition were significantly higher than for the control event condition. In the Ullman method, self-assessment of personal insight due to consideration of dream content was also significantly higher than for the event consideration condition. The findings support the view that benefits can be obtained from the consideration of dream content, in terms of identifying the waking life sources of dream content, and because personal insight may also occur. To investigate the mechanisms for the findings, the studies should be repeated with REM and non-REM dream reports, hypothesizing greater

  7. Video monitoring of brown planthopper predation in rice shows flaws of sentinel methods

    NARCIS (Netherlands)

    Zou, Yi; Kraker, De Joop; Bianchi, Felix J.J.A.; Telgen, Van Mario D.; Xiao, Haijun; Werf, Van Der Wopke

    2017-01-01

    Immobilized preys are routinely used in agro-ecological exposure studies to quantify predation of pests under field conditions, but this method has not been validated. Our purpose was to determine the validity of using immobilized adults of the major rice pest Nilaparvata lugens, brown plant hopper

  8. Exploration of a Method to Assess Children's Understandings of a Phenomenon after Viewing a Demonstration Show

    Science.gov (United States)

    DeKorver, Brittland K.; Choi, Mark; Towns, Marcy

    2017-01-01

    Chemical demonstration shows are a popular form of informal science education (ISE), employed by schools, museums, and other institutions in order to improve the public's understanding of science. Just as teachers employ formative and summative assessments in the science classroom to evaluate the impacts of their efforts, it is important to assess…

  9. A new method of MR total spine imaging for showing the brace effect in scoliosis

    Energy Technology Data Exchange (ETDEWEB)

    Schmitz, A.; Kandyba, J.; Koenig, R.; Jaeger, U.E.; Gieseke, J.; Schmitt, O. [Univ. of Bonn (Germany)

    2001-07-01

    Bracing is a method of early, nonsurgical treatment for scoliosis, but a hypokyphotic effect on the thoracic spine is reported. We developed a magnetic resonance tomography (MR) procedure presenting an image of the whole spine in the coronal and sagittal planes (MR total spine imaging), and studied the brace effect, using this technique. We examined 26 female patients with idiopathic scoliosis treated with a Cheneau brace (mean age, 13.2 years; mean duration of brace treatment at the time of investigation, 1.5 years). The MR examinations were performed with the patient in the supine position with and without the brace in direct sequence. As measured on the coronal MR images, the thoracic curve was corrected, on average, from 29 deg to 22 deg (mean correction, 24%). There was a slight reduction in the sagittal Cobb angle measured between T4 and T12 (mean sagittal Cobb angle without brace, 14 deg ; with brace, 12 deg), which was still a significant change. MR total spine imaging could be a useful tool for studying the brace effect in scoliosis in two planes. Using this technique, we found reduced sagittal Cobb angles for the thoracic kyphosis with brace. Because there is no radiation exposure, the MR procedure has a potential use in the monitoring of brace treatment. (author)

  10. Considerations and methods for the changes detection using satellite images in the Municipality of Paipa

    International Nuclear Information System (INIS)

    Riano M, Orlando

    2002-01-01

    In this article the considerations and methods are presented for the changes detection in the earth covering, using two images Landsat TM of different dates for an area of the municipality of Paipa, Boyaca. The changes detection has become an important application of the multi-spectral data and multi-temporal of the satellites programs for studies of natural resources Landsat, TM and Spot, in such a way that is possible to determine the types and extension of the changes that are given in the environment. To carry out this process some digital techniques they have been used for changes detection, such as: images superposition, differences between images and analysis of main components. These techniques allowed to observe and to analyze changes in the use and covering of the earth in this municipality

  11. EXPLANATORY METHODS OF MARKETING DATA ANALYSIS – THEORETICAL AND METHODOLOGICAL CONSIDERATIONS

    Directory of Open Access Journals (Sweden)

    Rozalia GABOR

    2010-01-01

    Full Text Available Explanatory methods of data analysis – also named by some authors supervised learning methods - enable researchers to identify and analyse configurations of relations between two or several variables, most of them with a high accuracy, as there is possibility of testing statistic significance by calculating the confidence level associated with validation of relation concerned across the entire population and not only the surveyed sample. The paper shows some of these methods, respectively: variance analysis, covariance analysis, segmentation and discriminant analysis with the mention - for every method – of applicability area for marketing research.

  12. Consideration of relativistic effects in band structure calculations based on the empirical tight-binding method

    International Nuclear Information System (INIS)

    Hanke, M.; Hennig, D.; Kaschte, A.; Koeppen, M.

    1988-01-01

    The energy band structure of cadmium telluride and mercury telluride materials is investigated by means of the tight-binding (TB) method considering relativistic effects and the spin-orbit interaction. Taking into account relativistic effects in the method is rather simple though the size of the Hamilton matrix doubles. Such considerations are necessary for the interesting small-interstice semiconductors, and the experimental results are reflected correctly in the band structures. The transformation behaviour of the eigenvectors within the Brillouin zone gets more complicated, but is, nevertheless, theoretically controllable. If, however, the matrix elements of the Green operator are to be calculated, one has to use formula manipulation programmes in particular for non-diagonal elements. For defect calculations by the Koster-Slater theory of scattering it is necessary to know these matrix elements. Knowledge of the transformation behaviour of eigenfunctions saves frequent diagonalization of the Hamilton matrix and thus permits a numerical solution of the problem. Corresponding results for the sp 3 basis are available

  13. Considerable improvement of entanglement swapping by considering multiphoton transitions via cavity quantum electrodynamics method

    Science.gov (United States)

    Pakniat, R.; Soltani, M.; Tavassoly, M. K.

    2018-03-01

    Recently we studied the effect of photon addition in the initial coherent field on the entanglement swapping which causes some improvements in the process [Soltani et al., Int. J. Mod. Phys. B 31, 1750198 (2017)]. In this paper, we investigate the influence of multiphoton transitions in the atom-field interaction based on the cavity quantum electrodynamics on the entanglement swapping and show its considerable constructive effect on this process. The presented model consists of two two-level atoms namely A1 and A2 and two distinct cavity fields F1 and F2. Initially, the atoms are prepared in a maximally entangled state and the fields in the cavities are prepared in hybrid entangled state of number and coherent states, separately. Making the atom A2 to interact with the field F1 (via the generalized Jaynes-Cummings model which allows m-photon transitions between atomic levels in the emission and absorption processes) followed by their detection allows us to arrive at the entanglement swapping from the two atoms A1, A2 and the two fields F1, F2 to the atom-field A1-F2 system. Then, we pay our attention to the time evolution of success probability of detecting processes and fidelity. Also, to determine the amount of entanglement of the generated entangled state in the swapping process, the linear entropy is evaluated and the effect of parameter m concerning the multiphoton transitions on these quantities is investigated, numerically. It is observed that, by increasing the number of photons in the transition process, one may obtain considerable improvement in the relevant quantities of the entanglement swapping. In detail, the satisfactorily acceptable values 1 and 0.5 corresponding to success probability and fidelity are obtained for most of the times during observing of the above-mentioned procedure. We concluded that the presented formalism in this paper is much more advantageous than our presentation model in our earlier work mentioned above.

  14. Ions extraction and collection using the RF resonance method and taking into consideration the sputtering loss

    International Nuclear Information System (INIS)

    Xie Guofeng; Wang Dewu; Ying Chuntong

    2005-01-01

    One-dimensional ions extraction and collection using the RF resonance method is studied by PIC-MCC simulation. The energy and angle distribution of extracted ions is recorded and the sputtering loss is calculated. The results show that compared with parallel electrode method, RF resonance method has advantages such as shorter extraction time, lower collision loss and sputtering loss and higher collection ratio; the extraction time and collision loss are decreased with increasing extraction voltage, but the sputtering loss increases and collection ratio decreases; collision loss is decreased with increasing magnetic field, but the sputtering loss increases and collection ratio decreases. (authors)

  15. Considerations on Applying the Method for Assessing the Level of Safety at Work

    Directory of Open Access Journals (Sweden)

    Costica Bejinariu

    2017-07-01

    Full Text Available The application of the method for assessing the level of safety at work starts with a document that contains the cover page, the description of the company (name, location, core business, organizational chart etc., description of the work system, a detailed list of its components, and a brief description of the assessment method. It continues with a Microsoft Excel document, which represents the actual application of the method and, finally, there is another document presenting conclusions, proposals, and prioritizations, which leads to the execution of the Prevention and Protection Plan. The present paper approaches the issue of developing the Microsoft Excel document, an essential part of the method for assessing the level of safety at work. The document is divided into a variable number of worksheets, showing the risk categories of general, specific, and management.

  16. Considerations for the independent reaction times and step-by-step methods for radiation chemistry simulations

    Science.gov (United States)

    Plante, Ianik; Devroye, Luc

    2017-10-01

    Ionizing radiation interacts with the water molecules of the tissues mostly by ionizations and excitations, which result in the formation of the radiation track structure and the creation of radiolytic species such as H.,.OH, H2, H2O2, and e-aq. After their creation, these species diffuse and may chemically react with the neighboring species and with the molecules of the medium. Therefore radiation chemistry is of great importance in radiation biology. As the chemical species are not distributed homogeneously, the use of conventional models of homogeneous reactions cannot completely describe the reaction kinetics of the particles. Actually, many simulations of radiation chemistry are done using the Independent Reaction Time (IRT) method, which is a very fast technique to calculate radiochemical yields but which do not calculate the positions of the radiolytic species as a function of time. Step-by-step (SBS) methods, which are able to provide such information, have been used only sparsely because these are time-consuming in terms of calculation. Recent improvements in computer performance now allow the regular use of the SBS method in radiation chemistry. The SBS and IRT methods are both based on the Green's functions of the diffusion equation (GFDE). In this paper, several sampling algorithms of the GFDE and for the IRT method are presented. We show that the IRT and SBS methods are exactly equivalent for 2-particles systems for diffusion and partially diffusion-controlled reactions between non-interacting particles. We also show that the results obtained with the SBS simulation method with periodic boundary conditions are in agreement with the predictions by classical reaction kinetics theory, which is an important step towards using this method for modelling of biochemical networks and metabolic pathways involved in oxidative stress. Finally, the first simulation results obtained with the code RITRACKS (Relativistic Ion Tracks) are presented.

  17. Specific Consideration on Superior Performance and Evaluation Methods of Polymer-housed Surge Arresters

    Science.gov (United States)

    Ishizaki, Yoshihiro; Kobayashi, Misao; Suzuki, Hironori; Futagami, Koichi

    It is very suitable to select the polymer materials for the housings of surge arresters (SAs), because the polymer materials are generally soft and light weight. Therefore, many kinds of polymer-housed SAs using various polymer materials have been developed, and expanding into many countries. Considering these backgrounds, the JEC technical report (JEC-TR) 23002-2008; polymer-housed surge arrester(1) has been established based on the existent relevant standards of arresters, such as JEC-2371-2003; Insulator-housed surge arresters(2) and IEC 60099-4 Edition 2.2, Metal-oxide surge arresters (MOSAs) without gaps for a.c. systems(3) in order to introduce the technology and provide a common guide for testing of polymer-housed SAs. According as the JEC-TR, the various new applications of the polymer-housed SAs, which are caused by superior advantages such as compact, light weight, safe failure mode, anti-seismic performance, anti-pollution performance and cost efficiency design, have been realized recently in Japan. Therefore, this paper gives specific consideration on the superior performance of the polymer-housed SAs and the evaluation methods of the polymer-housed SAs, because there are some issues in the existent standards to be solved.

  18. Ab initio chemical safety assessment: A workflow based on exposure considerations and non-animal methods

    OpenAIRE

    Berggren, Elisabet; White, Andrew; Ouedraogo, Gladys; Paini, Alicia; Richarz, Andrea-Nicole; Bois, Frederic Y.; Exner, Thomas; Leite, Sofia; Grunsven, Leo A. van; Worth, Andrew; Mahony, Catherine

    2017-01-01

    Highlights • A workflow for an exposure driven chemical safety assessment to avoid animal testing. • Hypothesis based on existing data, in silico modelling and biokinetic considerations. • A tool to inform targeted and toxicologically relevant in vitro testing.

  19. Consideration of a design optimization method for advanced nuclear power plant thermal-hydraulic components

    International Nuclear Information System (INIS)

    Ridluan, Artit; Tokuhiro, Akira; Manic, Milos; Patterson, Michael; Danchus, William

    2009-01-01

    In order to meet the global energy demand and also mitigate climate change, we anticipate a significant resurgence of nuclear power in the next 50 years. Globally, Generation III plants (ABWR) have been built; Gen' III+ plants (EPR, AP1000 others) are anticipated in the near term. The U.S. DOE and Japan are respectively pursuing the NGNP and MSFR. There is renewed interest in closing the fuel cycle and gradually introducing the fast reactor into the LWR-dominated global fleet. In order to meet Generation IV criteria, i.e. thermal efficiency, inherent safety, proliferation resistance and economic competitiveness, plant and energy conversion system engineering design have to increasingly meet strict design criteria with reduced margin for reliable safety and uncertainties. Here, we considered a design optimization approach using an anticipated NGNP thermal system component as a Case Study. A systematic, efficient methodology is needed to reduce time consuming trial-and-error and computationally-intensive analyses. We thus developed a design optimization method linking three elements; that is, benchmarked CFD used as a 'design tool', artificial neural networks (ANN) to accommodate non-linear system behavior and enhancement of the 'design space', and finally, response surface methodology (RSM) to optimize the design solution with targeted constraints. The paper presents the methodology including guiding principles, an integration of CFD into design theory and practice, consideration of system non-linearities (such as fluctuating operating conditions) and systematic enhancement of the design space via application of ANN, and a stochastic optimization approach (RSM) with targeted constraints. Results from a Case Study optimizing the printed circuit heat exchanger for the NGNP energy conversion system will be presented. (author)

  20. A review of Web information seeking research: considerations of method and foci of interest

    Directory of Open Access Journals (Sweden)

    Konstantina Martzoukou

    2005-01-01

    Full Text Available Introduction. This review shows that Web information seeking research suffers from inconsistencies in method and a lack of homogeneity in research foci. Background. Qualitative and quantitative methods are needed to produce a comprehensive view of information seeking. Studies also recommend observation as one of the most fundamental ways of gaining direct knowledge of behaviour. User-centred research emphasises the importance of holistic approaches, which incorporate physical, cognitive, and affective elements. Problems. Comprehensive studies are limited; many approaches are problematic and a consistent methodological framework has not been developed. Research has often failed to ensure appropriate samples that ensure both quantitative validity and qualitative consistency. Typically, observation has been based on simulated rather than real information needs and most studies show little attempt to examine holistically different characteristics of users in the same research schema. Research also deals with various aspects of cognitive style and ability with variant definitions of expertise and different layers of user experience. Finally the effect of social and cultural elements has not been extensively investigated. Conclusion. The existing limitations in method and the plethora of different approaches allow little progress and fewer comparisons across studies. There is urgent need for establishing a theoretical framework on which future studies can be based so that information seeking behaviour can be more holistically understood, and results can be generalised.

  1. Recruitment Methods and Show Rates to a Prostate Cancer Early Detection Program for High-Risk Men: A Comprehensive Analysis

    Science.gov (United States)

    Giri, Veda N.; Coups, Elliot J.; Ruth, Karen; Goplerud, Julia; Raysor, Susan; Kim, Taylor Y.; Bagden, Loretta; Mastalski, Kathleen; Zakrzewski, Debra; Leimkuhler, Suzanne; Watkins-Bruner, Deborah

    2009-01-01

    Purpose Men with a family history (FH) of prostate cancer (PCA) and African American (AA) men are at higher risk for PCA. Recruitment and retention of these high-risk men into early detection programs has been challenging. We report a comprehensive analysis on recruitment methods, show rates, and participant factors from the Prostate Cancer Risk Assessment Program (PRAP), which is a prospective, longitudinal PCA screening study. Materials and Methods Men 35–69 years are eligible if they have a FH of PCA, are AA, or have a BRCA1/2 mutation. Recruitment methods were analyzed with respect to participant demographics and show to the first PRAP appointment using standard statistical methods Results Out of 707 men recruited, 64.9% showed to the initial PRAP appointment. More individuals were recruited via radio than from referral or other methods (χ2 = 298.13, p < .0001). Men recruited via radio were more likely to be AA (p<0.001), less educated (p=0.003), not married or partnered (p=0.007), and have no FH of PCA (p<0.001). Men recruited via referrals had higher incomes (p=0.007). Men recruited via referral were more likely to attend their initial PRAP visit than those recruited by radio or other methods (χ2 = 27.08, p < .0001). Conclusions This comprehensive analysis finds that radio leads to higher recruitment of AA men with lower socioeconomic status. However, these are the high-risk men that have lower show rates for PCA screening. Targeted motivational measures need to be studied to improve show rates for PCA risk assessment for these high-risk men. PMID:19758657

  2. Numerical consideration for multiscale statistical process control method applied to nuclear material accountancy

    International Nuclear Information System (INIS)

    Suzuki, Mitsutoshi; Hori, Masato; Asou, Ryoji; Usuda, Shigekazu

    2006-01-01

    The multiscale statistical process control (MSSPC) method is applied to clarify the elements of material unaccounted for (MUF) in large scale reprocessing plants using numerical calculations. Continuous wavelet functions are used to decompose the process data, which simulate batch operation superimposed by various types of disturbance, and the disturbance components included in the data are divided into time and frequency spaces. The diagnosis of MSSPC is applied to distinguish abnormal events from the process data and shows how to detect abrupt and protracted diversions using principle component analysis. Quantitative performance of MSSPC for the time series data is shown with average run lengths given by Monte-Carlo simulation to compare to the non-detection probability β. Recent discussion about bias corrections in material balances is introduced and another approach is presented to evaluate MUF without assuming the measurement error model. (author)

  3. Meta-Analysis of Quantification Methods Shows that Archaea and Bacteria Have Similar Abundances in the Subseafloor

    Science.gov (United States)

    May, Megan K.; Kevorkian, Richard T.; Steen, Andrew D.

    2013-01-01

    There is no universally accepted method to quantify bacteria and archaea in seawater and marine sediments, and different methods have produced conflicting results with the same samples. To identify best practices, we compiled data from 65 studies, plus our own measurements, in which bacteria and archaea were quantified with fluorescent in situ hybridization (FISH), catalyzed reporter deposition FISH (CARD-FISH), polyribonucleotide FISH, or quantitative PCR (qPCR). To estimate efficiency, we defined “yield” to be the sum of bacteria and archaea counted by these techniques divided by the total number of cells. In seawater, the yield was high (median, 71%) and was similar for FISH, CARD-FISH, and polyribonucleotide FISH. In sediments, only measurements by CARD-FISH in which archaeal cells were permeabilized with proteinase K showed high yields (median, 84%). Therefore, the majority of cells in both environments appear to be alive, since they contain intact ribosomes. In sediments, the sum of bacterial and archaeal 16S rRNA gene qPCR counts was not closely related to cell counts, even after accounting for variations in copy numbers per genome. However, qPCR measurements were precise relative to other qPCR measurements made on the same samples. qPCR is therefore a reliable relative quantification method. Inconsistent results for the relative abundance of bacteria versus archaea in deep subsurface sediments were resolved by the removal of CARD-FISH measurements in which lysozyme was used to permeabilize archaeal cells and qPCR measurements which used ARCH516 as an archaeal primer or TaqMan probe. Data from best-practice methods showed that archaea and bacteria decreased as the depth in seawater and marine sediments increased, although archaea decreased more slowly. PMID:24096423

  4. Summary of PRA assessment of transient accident risks, human factors considerations, and PRA methods and applications

    International Nuclear Information System (INIS)

    Carnino, A.

    1984-01-01

    This chapter reviews the progress made in the probabilistic risk assessment (PRA) area to help in solving operational transient problems and to integrate human factors considerations, as discussed at the American Nuclear Society Topical Meeting on Anticipated and Abnormal Plant Transients in Light Water Reactors. Topics considered include core-melt frequency, external events (e.g., fires, floods), diagnostic errors, and operator aids. It is concluded that confidence in PRA results, predictions and uses for decisions in both the safety of the plants and their availability will improve

  5. A method to determine the mammographic regions that show early changes due to the development of breast cancer

    Science.gov (United States)

    Karemore, Gopal; Nielsen, Mads; Karssemeijer, Nico; Brandt, Sami S.

    2014-11-01

    It is well understood nowadays that changes in the mammographic parenchymal pattern are an indicator of a risk of breast cancer and we have developed a statistical method that estimates the mammogram regions where the parenchymal changes, due to breast cancer, occur. This region of interest is computed from a score map by utilising the anatomical breast coordinate system developed in our previous work. The method also makes an automatic scale selection to avoid overfitting while the region estimates are computed by a nested cross-validation scheme. In this way, it is possible to recover those mammogram regions that show a significant difference in classification scores between the cancer and the control group. Our experiments suggested that the most significant mammogram region is the region behind the nipple and that can be justified by previous findings from other research groups. This result was conducted on the basis of the cross-validation experiments on independent training, validation and testing sets from the case-control study of 490 women, of which 245 women were diagnosed with breast cancer within a period of 2-4 years after the baseline mammograms. We additionally generalised the estimated region to another, mini-MIAS study and showed that the transferred region estimate gives at least a similar classification result when compared to the case where the whole breast region is used. In all, by following our method, one most likely improves both preclinical and follow-up breast cancer screening, but a larger study population will be required to test this hypothesis.

  6. A method to determine the mammographic regions that show early changes due to the development of breast cancer

    International Nuclear Information System (INIS)

    Karemore, Gopal; Nielsen, Mads; Brandt, Sami S; Karssemeijer, Nico

    2014-01-01

    It is well understood nowadays that changes in the mammographic parenchymal pattern are an indicator of a risk of breast cancer and we have developed a statistical method that estimates the mammogram regions where the parenchymal changes, due to breast cancer, occur. This region of interest is computed from a score map by utilising the anatomical breast coordinate system developed in our previous work. The method also makes an automatic scale selection to avoid overfitting while the region estimates are computed by a nested cross-validation scheme. In this way, it is possible to recover those mammogram regions that show a significant difference in classification scores between the cancer and the control group. Our experiments suggested that the most significant mammogram region is the region behind the nipple and that can be justified by previous findings from other research groups. This result was conducted on the basis of the cross-validation experiments on independent training, validation and testing sets from the case-control study of 490 women, of which 245 women were diagnosed with breast cancer within a period of 2–4 years after the baseline mammograms. We additionally generalised the estimated region to another, mini-MIAS study and showed that the transferred region estimate gives at least a similar classification result when compared to the case where the whole breast region is used. In all, by following our method, one most likely improves both preclinical and follow-up breast cancer screening, but a larger study population will be required to test this hypothesis. (paper)

  7. A new PCR-based method shows that blue crabs (Callinectes sapidus (Rathbun)) consume winter flounder (Pseudopleuronectes americanus (Walbaum)).

    Science.gov (United States)

    Collier, Jackie L; Fitzgerald, Sean P; Hice, Lyndie A; Frisk, Michael G; McElroy, Anne E

    2014-01-01

    Winter flounder (Pseudopleuronectes americanus) once supported robust commercial and recreational fisheries in the New York (USA) region, but since the 1990s populations have been in decline. Available data show that settlement of young-of-the-year winter flounder has not declined as sharply as adult abundance, suggesting that juveniles are experiencing higher mortality following settlement. The recent increase of blue crab (Callinectes sapidus) abundance in the New York region raises the possibility that new sources of predation may be contributing to juvenile winter flounder mortality. To investigate this possibility we developed and validated a method to specifically detect winter flounder mitochondrial control region DNA sequences in the gut contents of blue crabs. A survey of 55 crabs collected from Shinnecock Bay (along the south shore of Long Island, New York) in July, August, and September of 2011 showed that 12 of 42 blue crabs (28.6%) from which PCR-amplifiable DNA was recovered had consumed winter flounder in the wild, empirically supporting the trophic link between these species that has been widely speculated to exist. This technique overcomes difficulties with visual identification of the often unrecognizable gut contents of decapod crustaceans, and modifications of this approach offer valuable tools to more broadly address their feeding habits on a wide variety of species.

  8. The clinical significance of computerized axial tomography (CAT) in consideration of conventional diagnostic methods

    International Nuclear Information System (INIS)

    Huenig, R.

    1976-01-01

    Regarding CAT of the intracranial region, the article informs on a) techniques of examination including the production of normal structures, b) the recognizable pathological changes, c) possibilities of enhancement, d) possibilities of course observation, e) limitations of the methods, as well as on f) risk/benefit aspects g) benefit/cost calculations as compared to conventional methods, and on h) the influence of CAT on the frequency of conventional methods of examination. Regarding CAT of the extracranial region, the information available up to the meeting is reported on. (orig./LH) [de

  9. Ab initio chemical safety assessment: A workflow based on exposure considerations and non-animal methods.

    Science.gov (United States)

    Berggren, Elisabet; White, Andrew; Ouedraogo, Gladys; Paini, Alicia; Richarz, Andrea-Nicole; Bois, Frederic Y; Exner, Thomas; Leite, Sofia; Grunsven, Leo A van; Worth, Andrew; Mahony, Catherine

    2017-11-01

    We describe and illustrate a workflow for chemical safety assessment that completely avoids animal testing. The workflow, which was developed within the SEURAT-1 initiative, is designed to be applicable to cosmetic ingredients as well as to other types of chemicals, e.g. active ingredients in plant protection products, biocides or pharmaceuticals. The aim of this work was to develop a workflow to assess chemical safety without relying on any animal testing, but instead constructing a hypothesis based on existing data, in silico modelling, biokinetic considerations and then by targeted non-animal testing. For illustrative purposes, we consider a hypothetical new ingredient x as a new component in a body lotion formulation. The workflow is divided into tiers in which points of departure are established through in vitro testing and in silico prediction, as the basis for estimating a safe external dose in a repeated use scenario. The workflow includes a series of possible exit (decision) points, with increasing levels of confidence, based on the sequential application of the Threshold of Toxicological (TTC) approach, read-across, followed by an "ab initio" assessment, in which chemical safety is determined entirely by new in vitro testing and in vitro to in vivo extrapolation by means of mathematical modelling. We believe that this workflow could be applied as a tool to inform targeted and toxicologically relevant in vitro testing, where necessary, and to gain confidence in safety decision making without the need for animal testing.

  10. Considerations Concerning the Application of Target Costing Method in the Industry of Dairy Products

    Directory of Open Access Journals (Sweden)

    Mortură Laura Alexandra

    2017-01-01

    Full Text Available In the present conditions of the market economy, which is in full process of globalization, theadaptation of the more complex and diverse needs of the final consumers, leads to a permanentcreation and development of new products and services by the entities in order to satisfy theseneeds. Thus, the entities must apply efficient and tested methods for determining and provisioningthe costs which will result from launching new products on the market, methods which wouldsupport and ensure the best quality – price report, and which are to reduce the production costs upto a level of not affecting the quality of the final product. Such a method, according to specialtyliterature is the modern method of Target Costing.

  11. Consideration about the contamination decreasing method of a crystalline lens in head CT

    International Nuclear Information System (INIS)

    Yamazaki, Shoichi; Matsueda, Katsuhiro; Matsumura, Mitsumi

    2002-01-01

    It is effective as a method for reducing the dose of a crystalline lens when enforcing Head CT to change the height of a bed, or it inquired. As a result of measuring, the dose of a crystalline lens became a low value sharply, when the quantity of a bed was moved to the up position. When a problem does not arise in diagnosis, the dose of a crystalline lens can be decreased by inspecting in the upper part as much as possible. As a method of reducing the dose of a crystalline lens, it is very useful. (author)

  12. Some considerations about literary analysis modern methods from a didactic perspective

    OpenAIRE

    Marialina Ana García Escobio; Moraima Pérez Barrera; María del Carmen Miló Anillo

    2016-01-01

    This article make it possible a close look to the modern methods of literary analysis, taking as the starting point what the teaching of literature in the joyful context should fulfill in the study of the literary play and the processes of reception and aesthetic statement, as well as the application of the aforementioned methods in the attempt to make the student arrive at rational position; But, at the same time, he/she should feel creator and coauthor of an event that should be lived from ...

  13. Measuring subjective meaning structures by the laddering method: Theoretical considerations and methodological problems

    DEFF Research Database (Denmark)

    Grunert, Klaus G.; Grunert, Suzanne C.

    1995-01-01

    Starting from a general model of measuring cognitive structures for predicting consumer behaviour, we discuss laddering as a possible method to obtain estimates of consumption-relevant cognitive structures which will have predictive validity. Four criteria for valid measurement are derived and ap...

  14. Practical considerations for conducting ecotoxicity test methods with manufactured nanomaterials: what have we learnt so far?

    NARCIS (Netherlands)

    Handy, R.D.; Brink, van den N.W.; Chappell, M.; Muhling, M.; Behra, R.; Dusinska, M.; Simpson, P.; Ahtiainen, J.; Jha, A.N.; Seiter, J.; Bednar, A.; Kennedy, A.; Fernandes, T.F.; Riediker, M.

    2012-01-01

    This review paper reports the consensus of a technical workshop hosted by the European network, NanoImpactNet (NIN). The workshop aimed to review the collective experience of working at the bench with manufactured nanomaterials (MNMs), and to recommend modifications to existing experimental methods

  15. Diversity and constructive conflict in stakeholder dialogue : Considerations for design and methods

    NARCIS (Netherlands)

    Cuppen, E.H.W.J.

    2011-01-01

    Diversity is generally recognized as a key issue for learning in stakeholder dialogue on wicked sustainability issues. Yet the question on how design of stakeholder dialogue and supporting methods actually enhance learning in stakeholder dialogue deserves more attention. This paper presents

  16. Consideration of the environmental effects on fatigue behavior of austenitic components. Calculation methods and practical application

    International Nuclear Information System (INIS)

    Seichter, Johannes; Reese, Sven H.; Klucke, Dietmar

    2012-01-01

    During the last years environmental effects on the fatigue behavior of nuclear power plant components has worldwide been discussed controversial with respect to the transferability of laboratory data on real components. A publication from Argonne National Laboratory on experimental results concerning environmental effects (air and LWR coolant) on fatigue of austenitic steels included a proposal on calculation methods concerning the lifetime reduction due to environmental effects. This calculation method, i.e. multiplication of the usage factor by a F(en), has been included into the ASME Code, Section III, Division I, as Code Case N-792 (fatigue evaluations including environmental effects). The presented contribution evaluates the practical application of this calculation procedure and demonstrates the determination of the usage factor of an austenitic component under environmental exposure.

  17. Methods and considerations to determine sphere center from terrestrial laser scanner point cloud data

    International Nuclear Information System (INIS)

    Rachakonda, Prem; Muralikrishnan, Bala; Lee, Vincent; Shilling, Meghan; Sawyer, Daniel; Cournoyer, Luc; Cheok, Geraldine

    2017-01-01

    The Dimensional Metrology Group at the National Institute of Standards and Technology is performing research to support the development of documentary standards within the ASTM E57 committee. This committee is addressing the point-to-point performance evaluation of a subclass of 3D imaging systems called terrestrial laser scanners (TLSs), which are laser-based and use a spherical coordinate system. This paper discusses the usage of sphere targets for this effort, and methods to minimize the errors due to the determination of their centers. The key contributions of this paper include methods to segment sphere data from a TLS point cloud, and the study of some of the factors that influence the determination of sphere centers. (paper)

  18. Self-regulation method: psychological, physiological and clinical considerations. An overview.

    Science.gov (United States)

    Ikemi, A; Tomita, S; Kuroda, M; Hayashida, Y; Ikemi, Y

    1986-01-01

    Body-oriented therapies as relaxation training and certain forms of meditation are gaining popularity in the treatment and prevention of psychosomatic disorders. In this paper, a new method of self-control called self-regulation method (SRM), derived from autogenic training and Zen meditation, is presented. The technique of SRM is introduced. Secondly, physiological studies on SRM using skin temperature, galvanic skin response, and cortical evoked potentials are presented. Thirdly, the results of psychological tests conducted on SRM are presented. These psycho-physiological studies suggest that SRM may elicit a state of 'relaxed alertness'. Fourthly, clinical applications of SRM are discussed, and 3 cases are presented. Finally, SRM is discussed in relation to the psychology and physiology of 'relaxed alertness'.

  19. Application of Time Delay Consideration on Bridge Vibration Control Method with Active Tendons

    Directory of Open Access Journals (Sweden)

    Lezin Seba MINSILI

    2010-12-01

    Full Text Available For many years bridge structures have been designed or constructed as passive structures that rely on their mass and solidity to resist external forces, while being incapable of adapting to the dynamics of an ever-changing environment. When the rigidity assumption is not met in particular for high-rise structures like bridge towers, a proper dynamic model should be established and conclusions made on the differential vibration of the tower when it is investigated out of the bridge system. The present work outlines a vibration control method by tendons on the tower of cable supported structures considering time delay effects, based on the discrete-time Linearization of the Feedback Gain Matrix. The efficiency of this vibration control method first proposed on the design process of a local bridge in Cameroon, is more compatible to the control of civil structures and is of great interest in accordance with simulation results.

  20. An Optimal Design Method of Centrifugal Compressors in Consideration of the Efficiency and the Noise

    International Nuclear Information System (INIS)

    Ha, K. G.; Sung, S. M.; Kang, S. H.

    2007-01-01

    A centrifugal compressor is a principal part of the fuelcell vehicles, aircraft and home appliances. Therefore not only efficiency but also compact size and a low operation RPM for noise reducing turn into important criteria of centrifugal compressors design. But those criteria are in conflict each other often. In the case of a RPM in particular, it is profitable to lower the RPM for a noise reduction and an endurance. But for a compact size and a light weight, the reverse has a beneficial effect undoubtedly. So it is necessary to introduce a new optimization concept in the centrifugal compressor design. An one dimensional optimal design method for the centrifugal compressor considering a impeller, a vaneless diffuser and a volute at a time is described. The new optimization process and underlying design methods of centrifugal compressors and some optimal design results are included in the paper

  1. Some considerations about literary analysis modern methods from a didactic perspective

    Directory of Open Access Journals (Sweden)

    Marialina Ana García Escobio

    2016-12-01

    Full Text Available This article make it possible a close look to the modern methods of literary analysis, taking as the starting point what the teaching of literature in the joyful context should fulfill in the study of the literary play and the processes of reception and aesthetic statement, as well as the application of the aforementioned methods in the attempt to make the student arrive at rational position; But, at the same time, he/she should feel creator and coauthor of an event that should be lived from a type of special reading done; Herein the importance of a system of methodological work that prepares the professors to contribute from each of the classes to the development of skills for the students´ literary analysis.

  2. Apparatus and method for optimal phase balancing using dynamic programming with spatial consideration

    Science.gov (United States)

    Robertazzi, Thomas G.; Skiena, Steven; Wang, Kai

    2017-08-08

    Provided are an apparatus and method for load-balancing of a three-phase electric power distribution system having a multi-phase feeder, including obtaining topology information of the feeder identifying supply points for customer loads and feeder sections between the supply points, obtaining customer information that includes peak customer load at each of the points between each of the feeder sections, performing a phase balancing analysis, and recommending phase assignment at the customer load supply points.

  3. Quantitative method for measurement of the Goos-Hanchen effect based on source divergence considerations

    International Nuclear Information System (INIS)

    Gray, Jeffrey F.; Puri, Ashok

    2007-01-01

    In this paper we report on a method for quantitative measurement and characterization of the Goos-Hanchen effect based upon the real world performance of optical sources. A numerical model of a nonideal plane wave is developed in terms of uniform divergence properties. This model is applied to the Goos-Hanchen shift equations to determine beam shift displacement characteristics, which provides quantitative estimates of finite shifts near critical angle. As a potential technique for carrying out a meaningful comparison with experiments, a classical method of edge detection is discussed. To this end a line spread Green's function is defined which can be used to determine the effective transfer function of the near critical angle behavior of divergent plane waves. The process yields a distributed (blurred) output with a line spread function characteristic of the inverse square root nature of the Goos-Hanchen shift equation. A parameter of interest for measurement is given by the edge shift function. Modern imaging and image processing methods provide suitable techniques for exploiting the edge shift phenomena to attain refractive index sensitivities of the order of 10 -6 , comparable with the recent results reported in the literature

  4. A Method to Select Software Test Cases in Consideration of Past Input Sequence

    International Nuclear Information System (INIS)

    Kim, Hee Eun; Kim, Bo Gyung; Kang, Hyun Gook

    2015-01-01

    In the Korea Nuclear I and C Systems (KNICS) project, the software for the fully-digitalized reactor protection system (RPS) was developed under a strict procedure. Even though the behavior of the software is deterministic, the randomness of input sequence produces probabilistic behavior of software. A software failure occurs when some inputs to the software occur and interact with the internal state of the digital system to trigger a fault that was introduced into the software during the software lifecycle. In this paper, the method to select test set for software failure probability estimation is suggested. This test set reflects past input sequence of software, which covers all possible cases. In this study, the method to select test cases for software failure probability quantification was suggested. To obtain profile of paired state variables, relationships of the variables need to be considered. The effect of input from human operator also have to be considered. As an example, test set of PZR-PR-Lo-Trip logic was examined. This method provides framework for selecting test cases of safety-critical software

  5. Considerations for Task Analysis Methods and Rapid E-Learning Development Techniques

    Directory of Open Access Journals (Sweden)

    Dr. Ismail Ipek

    2014-02-01

    Full Text Available The purpose of this paper is to provide basic dimensions for rapid training development in e-learning courses in education and business. Principally, it starts with defining task analysis and how to select tasks for analysis and task analysis methods for instructional design. To do this, first, learning and instructional technologies as visions of the future were discussed. Second, the importance of task analysis methods in rapid e-learning was considered, with learning technologies as asynchronous and synchronous e-learning development. Finally, rapid instructional design concepts and e-learning design strategies were defined and clarified with examples, that is, all steps for effective task analysis and rapid training development techniques based on learning and instructional design approaches were discussed, such as m-learning and other delivery systems. As a result, the concept of task analysis, rapid e-learning development strategies and the essentials of online course design were discussed, alongside learner interface design features for learners and designers.

  6. Consideration of the method of image diagnosis with respect to frontal lobe atrophy

    Science.gov (United States)

    Sato, K.; Sugawara, K.; Narita, Y.; Namura, I.

    1996-12-01

    Proposes a segmentation method for a quantitative image diagnosis as a means of realizing an objective diagnosis of the frontal lobe atrophy. From the data obtained on the grade of membership, the fractal dimensions of the cerebral tissue [cerebral spinal fluid (CSF), gray matter, and white matter] and the contours are estimated. The mutual relationship between the degree of atrophy and the fractal dimension has been analyzed based on the estimated fractal dimensions. Using a sample of 42 male and female cases, ranging In age from 50's to 70's, it has been concluded that the frontal lobe atrophy can be quantified by regarding it as an expansion of CSF region on the magnetic resonance imaging (MRI) of the brain. Furthermore, when the process of frontal lobe atrophy is separated into early and advanced stages, the volumetric change of CSF and white matter in frontal lobe displays meaningful differences between the two stages, demonstrating that the fractal dimension of CSF rises with the progress of atrophy. Moreover, an interpolation method for three-dimensional (3-D) shape reconstruction of the region of diagnostic interest is proposed and 3-D shape visualization, with respect to the degree and form of atrophy, is performed on the basis of the estimated fractal dimension of the segmented cerebral tissue.

  7. Design Considerations for Aural Vital Signs Using PZT Piezoelectric Ceramics Sensor Based on the Computerization Method

    Directory of Open Access Journals (Sweden)

    Jerapong Tantrakoon

    2007-11-01

    Full Text Available The purpose was to illustrate how system developed for measurement of the aural vital signs such as patient’s heart and lung sounds in the hospital. For heart sounds measurement must operate the frequency response between 20 – 800 Hz, and lung sounds measurement must operate the frequency response between 160 – 4,000 Hz. The method was designed PZT piezoelectric ceramics for both frequency response in the same PZT sensor. It converts a signal from aural vital sign form to voltage signal. The signal is suitably amplified and re-filtered in band pass frequency band. It is converted to digital signal by an analog to digital conversion circuitry developed for the purpose. The results were that all signals can fed to personal computer through the sound card port. With the supporting software for drawing of graphic on the screen, the signal for a specific duration is accessed and stored in the computer’s memory in term of each patient’s data. In conclusion, the data of each patient call dot pcg (.pcg for drawing graph and dot wave (.wave for sound listening or automatic sending via electronic mail to the physician for later analysis of interpreting the sounds on the basis of their time domain and frequency domain representation to diagnose heart disorders.

  8. Consideration on detection of irradiated rainbow trout by ESR method and 2-alkylcyclobutanone analysis

    International Nuclear Information System (INIS)

    Tanabe, Hiroko; Goto, Michiko

    2002-01-01

    Relative ESR strength of rib, backbone and opercular bone from irradiated culture rainbow trout was direct proportional to dose between 0.56kGy and 5.7kGy. Relative ESR strength of rib was higher than that of backbone. Although only 5mg of otolith was obtained from one rainbow trout, bone density of otolith is so high that relative ESR strength of otolith showed about 20-fold higher value than that of rib. In GCMS-SIM analysis of RCB, radiolytic compounds of lipid of fish meat, the amount of both DCB and TCB formed, estimated from ion concentrations of m/z98, were direct proportional to dose between 1.1kGy and 11.1kGy. Neither DCB nor TCB was detected in unirradiated sample. The ratio of amount of DCB formed to amount of TCB formed was nearly 4.4, which is the ratio of palmitic acid content to stearic acid content in rainbow trout, denoted in Standard Tables of Food Composition in Japan; Lipid composition of Foods. Finally, we propose to use detection of radiolytic compound, RCB, and measurement of ESR of high-density bone together for reliable identification of irradiated fish. (author)

  9. Consideration on detection of irradiated rainbow trout by ESR method and 2-alkylcyclobutanone analysis

    International Nuclear Information System (INIS)

    Tanabe, H.; Goto, M.

    2002-01-01

    R elative ESR strength of rib, backbone and opercular bone from irradiated culture rainbow trout was direct proportional to dose between 0.56kGy and 5.7kGy. Relative ESR strength of rib was higher than that of backbone. Although only 5mg of otolith was obtained from one rainbow trout, bone density of otolith is so high that relative ESR strength of otolith showed about 20-fold higher value than that of rib. In GCMS-SIM analysis of RGB, radiolytic compounds of lipid of fish meat, the amount of both DCB and TCB formed, estimated from ion concentrations of m/z98, were direct proportional to dose between 1.1kGy and 11.1kGy. Neither DCB nor TCB was detected in unirradiated sample. The ratio of amount of DCB formed to amount of TCB formed was nearly 4.4, which is the ratio of palmitic acid content to stearic acid content in rainbow trout, denoted in Standard Tables of Food Composition in Japan; Lipid composition of Foods. Finally, we propose to use detection of radiolytic compound, RCB, and measurement of ESR of high-density bone together for reliable identification of irradiated fish

  10. Blame and guilt - a mixed methods study of obstetricians' and midwives' experiences and existential considerations after involvement in traumatic childbirth.

    Science.gov (United States)

    Schrøder, Katja; Jørgensen, Jan S; Lamont, Ronald F; Hvidt, Niels C

    2016-07-01

    When complications arise in the delivery room, midwives and obstetricians operate at the interface of life and death, and in rare cases the infant or the mother suffers severe and possibly fatal injuries related to the birth. This descriptive study investigated the numbers and proportions of obstetricians and midwives involved in such traumatic childbirth and explored their experiences with guilt, blame, shame and existential concerns. A mixed methods study comprising a national survey of Danish obstetricians and midwives and a qualitative interview study with selected survey participants. The response rate was 59% (1237/2098), of which 85% stated that they had been involved in a traumatic childbirth. We formed five categories during the comparative mixed methods analysis: the patient, clinical peers, official complaints, guilt, and existential considerations. Although blame from patients, peers or official authorities was feared (and sometimes experienced), the inner struggles with guilt and existential considerations were dominant. Feelings of guilt were reported by 36-49%, and 50% agreed that the traumatic childbirth had made them think more about the meaning of life. Sixty-five percent felt that they had become a better midwife or doctor due to the traumatic incident. The results of this large, exploratory study suggest that obstetricians and midwives struggle with issues of blame, guilt and existential concerns in the aftermath of a traumatic childbirth. © 2016 Nordic Federation of Societies of Obstetrics and Gynecology.

  11. Control method for multi-input multi-output non-Gaussian random vibration test with cross spectra consideration

    Directory of Open Access Journals (Sweden)

    Ronghui ZHENG

    2017-12-01

    Full Text Available A control method for Multi-Input Multi-Output (MIMO non-Gaussian random vibration test with cross spectra consideration is proposed in the paper. The aim of the proposed control method is to replicate the specified references composed of auto spectral densities, cross spectral densities and kurtoses on the test article in the laboratory. It is found that the cross spectral densities will bring intractable coupling problems and induce difficulty for the control of the multi-output kurtoses. Hence, a sequential phase modification method is put forward to solve the coupling problems in multi-input multi-output non-Gaussian random vibration test. To achieve the specified responses, an improved zero memory nonlinear transformation is utilized first to modify the Fourier phases of the signals with sequential phase modification method to obtain one frame reference response signals which satisfy the reference spectra and reference kurtoses. Then, an inverse system method is used in frequency domain to obtain the continuous stationary drive signals. At the same time, the matrix power control algorithm is utilized to control the spectra and kurtoses of the response signals further. At the end of the paper, a simulation example with a cantilever beam and a vibration shaker test are implemented and the results support the proposed method very well. Keywords: Cross spectra, Kurtosis control, Multi-input multi-output, Non-Gaussian, Random vibration test

  12. Numerical analysis of laser welding with consideration analytical methods of determining phase transformations and mechanical properties of welded joint

    Directory of Open Access Journals (Sweden)

    Piekarska Wiesława

    2018-01-01

    Full Text Available The numerical analysis of laser welding process with consideration analytical methods determining phase transformations and mechanical properties of welded joints are presents in this paper. The analytical CCT diagram and final structural composition of S355 steel are presented. The empirical relations presents in paper are determined by chemical compositions investigated steel and cooling rate between temperatures 800-500°C (t8/5. Phase composition and mechanical properties each of structures of steel in weld and heat affected zone (HAZ are determined on the basis of analytical methods. Laser welded flat is used in numerical simulations in ABAQUS. Mathematical modes of volumetric welding source are used in the calculations. Temperature fields, shape and size of melting zone for selected points in the cross-section of the joint are determined on the basis of thermal cycles obtained numerical.

  13. A Maximum Power Point Tracking Control Method of a Photovoltaic Power Generator with Consideration of Dynamic Characteristics of Solar Cells

    Science.gov (United States)

    Watanabe, Takashi; Yoshida, Toshiya; Ohniwa, Katsumi

    This paper discusses a new control strategy for photovoltaic power generation systems with consideration of dynamic characteristics of the photovoltaic cells. The controller estimates internal currents of an equivalent circuit for the cells. This estimated, or the virtual current and the actual voltage of the cells are fed to a conventional Maximum-Power-Point-Tracking (MPPT) controller. Consequently, this MPPT controller still tracks the optimum point even though it is so designed that the seeking speed of the operating point is extremely high. This system may suit for applications, which are installed in rapidly changeable insolation and temperature-conditions e.g. automobiles, trains, and airplanes. The proposed method is verified by experiment with a combination of this estimating function and the modified Boehringer's MPPT algorithm.

  14. Investigation of cooling methods and thickness considerations in the filter/window assembly for synchrotron radiation beamlines

    International Nuclear Information System (INIS)

    Wang, Z.; Kuzay, T.M.; Hahn, U.

    1993-01-01

    Synchrotron x-ray windows are vacuum separators and are usually made of thin beryllium metal. Filters are provided upstream to absorb the soft x-rays so that the window can be protected from overheating, which could result in failure. The filters are made of thin carbon products or sometimes beryllium, the same material as the window. When the synchrotron x-rays pass through a filter or window, part of the photons will be absorbed by the filter or window. The absorbed photons cause heat to build up within the filter or window. Successful filter and window designs should effectively dissipate the heat generated by the absorbed photons and guarantee the safety of the filter and window. The cooling methods typically used in a filter or window design are conduction and radiation cooling or a combination of the two. The different cooling methods were first examined with regard to efficiency and effectiveness in different temperature ranges. Analysis results are presented for temperature distribution and corresponding thermal stresses in the filter and window. Another important issue to be resolved in designing a filter/window assembly is how to select the thickness of the filters and windows. This paper focuses on the criteria for choosing the thickness of a filter: whether it is better to use a few thick filters or a series of thin ones; how to determine the minimum/maximum thickness; and the difference in thickness considerations for the window versus the filter. Numerical investigations are presented

  15. Increased component safety through improved methods for residual stress analysis. Subprojects. Consideration of real component geometries (phase 1). Final report

    International Nuclear Information System (INIS)

    Nau, Andreas; Scholtes, B.

    2014-01-01

    -axial plane stress states were taken into account in this study. In the case of component's edges minor influences on the calculated stresses could be observed using standard calibration coefficients. Thus, a specific calibration is not considered necessary. The effects on shoulders could be assessed analogously. In the case of the claddings a remarkable influence could only be observed, if their thickness is below 2 mm. Essential benefits were reached through pre-experiments. As a consequence, the experimental execution was improved in terms of the material removal technique. The experimental data preparation was investigated in addition, which lead to the approach not to condition the experimental strains but rather the calculated stresses. This method is important for the experiments of phase 2 within this project. As a consequence of a successful project, the present knowledge base will be considerably improved and will be available for various engineering fields. Especially, the quantitative consideration of real residual stress states for optimized component designs will be feasible and finally the consequences of residual stresses an the component's safety, which are used in nuclear facilities, can be evaluated. The findings of the first numerical and theoretical research period (phase 1) at Kassel University are documented in this report.

  16. Introduction of a computer-based method for automated planning of reduction paths under consideration of simulated muscular forces.

    Science.gov (United States)

    Buschbaum, Jan; Fremd, Rainer; Pohlemann, Tim; Kristen, Alexander

    2017-08-01

    Reduction is a crucial step in the surgical treatment of bone fractures. Finding an optimal path for restoring anatomical alignment is considered technically demanding because collisions as well as high forces caused by surrounding soft tissues can avoid desired reduction movements. The repetition of reduction movements leads to a trial-and-error process which causes a prolonged duration of surgery. By planning an appropriate reduction path-an optimal sequence of target-directed movements-these problems should be overcome. For this purpose, a computer-based method has been developed. Using the example of simple femoral shaft fractures, 3D models are generated out of CT images. A reposition algorithm aligns both fragments by reconstructing their broken edges. According to the criteria of a deduced planning strategy, a modified A*-algorithm searches collision-free route of minimal force from the dislocated into the computed target position. Muscular forces are considered using a musculoskeletal reduction model (OpenSim model), and bone collisions are detected by an appropriate method. Five femoral SYNBONE models were broken into different fracture classification types and were automatically reduced from ten randomly selected displaced positions. Highest mean translational and rotational error for achieving target alignment is [Formula: see text] and [Formula: see text]. Mean value and standard deviation of occurring forces are [Formula: see text] for M. tensor fasciae latae and [Formula: see text] for M. semitendinosus over all trials. These pathways are precise, collision-free, required forces are minimized, and thus regarded as optimal paths. A novel method for planning reduction paths under consideration of collisions and muscular forces is introduced. The results deliver additional knowledge for an appropriate tactical reduction procedure and can provide a basis for further navigated or robotic-assisted developments.

  17. A new method for calculating gas content of coal reservoirs with consideration of a micro-pore overpressure environment

    Directory of Open Access Journals (Sweden)

    Jinxing Song

    2017-05-01

    Full Text Available When the gas content of a coal reservoir is calculated, the reservoir pressure measured by well logging and well testing is generally used for inversion calculation instead of gas pressure. However, the calculation result is not accurate because the reservoir pressure is not equal to the gas pressure in overpressure environments. In this paper, coal samples of different ranks in Shanxi and Henan are collected for testing the capillary pressure of coal pores. Based on the formation process of CBM reservoirs and the hydrocarbon generation and expulsion history of coal beds, the forming mechanisms of micro-pore overpressure environments in coal reservoirs were analyzed. Accordingly, a new method for calculating the gas content of coal reservoirs with consideration of a micro-pore overpressure environment was developed. And it was used to calculate the gas content of No. 1 coal bed of the 2nd member of Lower Permian Shanxi Fm in the Zhongmacun Coal Mine in Jiaozuo, Henan. It is indicated that during the formation and evolution of coals, some solid organic matters were converted into gas and water, and gas–water contact is surely formed in pores. In the end, capillary pressure is generated, so the gas pressure in micro-pores is much higher than the hydrostatic column pressure, which results in a micro-pore overpressure environment. Under such an environment, gas pressure is higher than reservoir pressure, so the gas content of coal reservoirs calculated previously based on the conventional reservoir pressure evaluation are usually underestimated. It is also found that the micro-pore overpressure environment exerts a dominating effect on the CBM content calculation of 3–100 nm pores, especially that of 3–10 nm pores, but a little effect on that of pores >100 nm. In conclusion, this new method clarifies the pressure environment of CBM gas reservoirs, thereby ensuring the calculation accuracy of gas content of coal reservoirs.

  18. Application of Tikhonov regularization method to wind retrieval from scatterometer data II: cyclone wind retrieval with consideration of rain

    International Nuclear Information System (INIS)

    Zhong Jian; Huang Si-Xun; Fei Jian-Fang; Du Hua-Dong; Zhang Liang

    2011-01-01

    According to the conclusion of the simulation experiments in paper I, the Tikhonov regularization method is applied to cyclone wind retrieval with a rain-effect-considering geophysical model function (called GMF+Rain). The GMF+Rain model which is based on the NASA scatterometer-2 (NSCAT2) GMF is presented to compensate for the effects of rain on cyclone wind retrieval. With the multiple solution scheme (MSS), the noise of wind retrieval is effectively suppressed, but the influence of the background increases. It will cause a large wind direction error in ambiguity removal when the background error is large. However, this can be mitigated by the new ambiguity removal method of Tikhonov regularization as proved in the simulation experiments. A case study on an extratropical cyclone of hurricane observed with SeaWinds at 25-km resolution shows that the retrieved wind speed for areas with rain is in better agreement with that derived from the best track analysis for the GMF+Rain model, but the wind direction obtained with the two-dimensional variational (2DVAR) ambiguity removal is incorrect. The new method of Tikhonov regularization effectively improves the performance of wind direction ambiguity removal through choosing appropriate regularization parameters and the retrieved wind speed is almost the same as that obtained from the 2DVAR. (electromagnetism, optics, acoustics, heat transfer, classical mechanics, and fluid dynamics)

  19. Reliability of Doppler and stethoscope methods of determining systolic blood pressures: considerations for calculating an ankle-brachial index.

    Science.gov (United States)

    Chesbro, Steven B; Asongwed, Elmira T; Brown, Jamesha; John, Emmanuel B

    2011-01-01

    The purposes of this study were to: (1) identify the interrater and intrarater reliability of systolic blood pressures using a stethoscope and Doppler to determine an ankle-brachial index (ABI), and (2) to determine the correlation between the 2 methods. Peripheral arterial disease (PAD) affects approximately 8 to 12 million people in the United States, and nearly half of those with this disease are asymptomatic. Early detection and prompt treatment of PAD will improve health outcomes. It is important that clinicians perform tests that determine the presence of PAD. Two individual raters trained in ABI procedure measured the systolic blood pressures of 20 individuals' upper and lower extremities. Standard ABI measurement protocols were observed. Raters individually recorded the systolic blood pressures of each extremity using a stethoscope and a Doppler, for a total of 640 independent measures. Interrater reliability of Doppler measurements to determine SBP at the ankle was very strong (intraclass correlation coefficient [ICC], 0.93-0.99) compared to moderate to strong reliability using a stethoscope (ICC, 0.64-0.87). Agreement between the 2 devices to determine SBP was moderate to very weak (ICC, 0.13-0.61). Comparisons of the use of Doppler and stethoscope to determine ABI showed weak to very weak intrarater correlation (ICC, 0.17-0.35). Linear regression analysis of the 2 methods to determine ABI showed positive but weak to very weak correlations (r2 = .013, P = .184). A Doppler ultrasound is recommended over a stethoscope for accuracy in systolic pressure readings for ABI measurements.

  20. Laser-optical methods for earlier diagnostics of plant and seed diseases in various habitant media taking into consideration anthropogenic and biological pollution

    Science.gov (United States)

    Lisker, Joseph S.; Dmitriev, Andrey P.

    1999-12-01

    By the method of the computer laser-optical photometry the investigation of the cereal stability for the various diseases taken into consideration the stability of tomato seeds to their interaction with the phytopathogenes and the phytotoxicity of microscopic fungi on the wheat seedlings was carried out. Original result for the investigation of optical-physiological characteristics of plants and seeds are shown.

  1. Considerations Regarding the Expert Systems in the Economy and the Use Method of the Production Systems Based on Rules

    Directory of Open Access Journals (Sweden)

    Eugenia IANCU

    2010-01-01

    Full Text Available As it is known, the expert systems- particularlyreferring to the ones in the economical area, represent a currentissue of our days, them being approached by all the economicalbranches. Starting from these aspects, we wish to present somenecessary principles and considerations regarding the expertsystems, representation of the facts, systems based onproduction rules. The objective of this paper is aimed toidentifying the exigencies of the production system based onrules.

  2. The effect of PBL and film showing, frequent quizzes and lecture-based method on short-term performance of dentistry students

    Directory of Open Access Journals (Sweden)

    Sadr Lahijani M.S

    2004-01-01

    Full Text Available Background: Advocates have proposed that frequent testing increases the effectiveness of instruction by encouraging learners to study and review more often. It has also been argued that in this way, student errors can be identified and corrected earlier and good performance can be recognized, leading to more positive attitudes toward learning process. In problem-based learning (PBL, medical students reportedly take a more active role in learning and have better recall than students in a conventional learning environment. The hypothetical benefits of a PBL and studentbased environment and use of films in the class are the development of self-learning and problem-solving skills and enhancement of knowledge and motivation. Purpose: To examine the effect of combination of PBL method and film showing on the short-term performance of dentistry students and to compare it with lecture-based method and frequent quizzes. Methods: All students of 3 years (from 2000 till 2002 that had theoretical endodontic course (part 1 participated in this descriptive-analytic study. The scores of final examinations of this course were obtained from their files. Data were analyzed by SPSS software & ANOVA. Results: The results showed that by changing the way of learning (PBL and film showing in 2001, there was a statistical difference between scores of the students of 2000 and 2001. Also there was a statistical difference with the students’ scores in 2002- the group with frequent quizzes. Conclusion: The variables such as changing the way of learning, using different methods in teaching, showing scientific films in class or, as a whole, active learning have significant effects on the results of final examination. Key Words: PBL, lecture based method, education, frequent quizzes

  3. Rapid detection of methicillin-resistant Staphylococcus aureus directly from clinical samples: methods, effectiveness and cost considerations

    Directory of Open Access Journals (Sweden)

    Stürenburg, Enno

    2009-07-01

    Full Text Available Methicillin-resistant Staphylococcus aureus (MRSA isolates is a serious public health problem whose ever-increasing rate is commensurate with the pressure it is exerting on the healthcare system. At present, more than 20% of clinical S. aureus isolates in German hospitals are methicillin resistant. Strategies from low-prevalence countries show that this development is not necessarily inevitable. In the Scandinavian countries and the Netherlands, thanks to a rigorous prevention programme, MRSA prevalence has been kept at an acceptably low level (<1–3%. Central to these ‘search and destroy’ control strategies is an admission screening using several MRSA swabs taken from mucocutaneous colonisation sites of high-risk patients (‘MRSA surveillance’. It has also been reported that the speed with which MRSA carriage is detected has an important role to play, as it is a key component of any effective strategy to prevent the pathogen from spreading. Since MRSA culturing involves a 2–3 day delay before the final results are available, rapid detection techniques (commonly referred to as ‘MRSA rapid tests’ using PCR methods and, most recently, rapid culturing methods have been developed. The implementation of rapid tests reduces the time of detection of MRSA carriers from 48–72 to 2–5 h. Clinical evaluation data have shown that MRSA can thus be detected with very high sensitivity. Specificity however is sometimes impaired due to false-positive PCR signals occurring in mixed flora specimens. In order to rule out any false-positive PCR results, a culture screen must always be carried out simultaneously.The data provide preliminary evidence that a PCR assay can reduce nosocomial MRSA transmission in high-risk patients or high-risk areas, whereas an approach that screens all patients admitted to the hospital is probably not effective. Information concerning the cost-effectiveness of rapid MRSA tests is still sparse and thus the issue remains

  4. Failure to label red blood cells adequately in daily practice using an in vivo method: methodological and clinical considerations

    International Nuclear Information System (INIS)

    Hambye, A.S.; Vandermeiren, R.; Vervaet, A.; Vandevivere, J.

    1995-01-01

    This study was conducted to evaluate the frequency and possible causes of poor red blood cell (RBC) labelling when performing equilibrium gated blood pool (GBP) radionuclide angiography at rest with an in vivo method. The influence of the mode of administration on tagging efficiency was studied. The patients were subclassified into four groups according to the way both molecules involved in the tagging procedure were administered. When poor image quality was found, the labelling efficiency was quantified and the frequency of failed tagging in each group was calculated. A significant association was found between poor labelling and the use of a Teflon catheter or butterfly needle for the injection of the stannous agent. In another 737 patients a strict administration protocol was applied to analyse the frequency of poor tagging and its possible causes. Suboptimal image quality was present in 88 patients. Quantitatively confirmed poor tagging was present in 36 of the 88; the remaining 52 patients showed borderline normal labelling. Drug interference was studied by comparing the medications used by the 36 patients showing poor binding with those used by 44 control patients. A significant relationship was found between the use of heparin or chemotherapy and the tagging. A significant correlation was found between advanced age and poor labelling efficiency. Finally, in 36 patients with poor labelling, a second GBP test was performed. This allowed us to evaluate the accuracy of the obtained ejection fraction value when a suboptimal image set is used, and to assess the feasibility of using the new kit in daily practice. (orig.)

  5. Development of computational dynamic properties analysis method and optimum design method of tissue construction under consideration of microstructure of materials for nuclear power

    International Nuclear Information System (INIS)

    Shiraishi, Haruki; Tabuchi, Masaaki; Nakasone, Yuji

    1999-01-01

    A practical reactor core material produces particles by irradiation in the matrix. The second phase particle lattice was defined and the effects of its basic parameters on the stress-strain curve were evaluated. As the basic parameters, 0.01 to 0.95 μm of particle diameter, 1.0μm of grain spacing and 0.3 of work-hardening exponent were used. The effect of the particle diameter on the stress-strain curve was studied by the large deformation finite element method. The concentration area of distortion was produced from the back of the second phase particles, and its process specified the sharp of stress-strain curve. The calculation method did not assume breaking of particles and separation of the interface of particle and matrix. So that, the values obtained showed the upper limits of strength, ductility and fracture toughness of the composite materials. (S.Y.)

  6. Performance analysis of a Miller cycle engine by an indirect analysis method with sparking and knock in consideration

    International Nuclear Information System (INIS)

    Wang, Yuanfeng; Zu, Bingfeng; Xu, Yuliang; Wang, Zhen; Liu, Jie

    2016-01-01

    Highlights: • A quasi-dimensional model was adopted to study Miller cycle engine’s performance. • A new indirect performance analysis method was proposed. • The definition of effective compression ratio was modified. • The modified effective compression ratio takes the trapped mixture mass in account. • The factors limiting the fuel economy in Miller cycle engine were found out. - Abstract: In this paper, a full-factorial design of experiment was applied to thoroughly investigate the effects of compression ratio, intake valve closing retardation angle, and engine speed on the fuel consumption performance and power performance of the Miller cycle engine based on a quasi-dimensional simulation model. A new indirect analysis method based on formula derivation and main effect analysis was proposed to simplify the complex relationship between the design factors and the performance parameters. The definition of effective compression ratio was modified to take account of the actual mass of mixture trapped in the cylinder. The results show that the distributions of brake mean effective pressure and brake specific fuel consumption can be regarded as the re-organization results from the distributions of volumetric efficiency and indicated efficiency. The intake valve closing retardation angle has a strong negative correlation with volumetric efficiency. The modified effective compression ratio is the approximate product of the compression ratio and the volumetric efficiency, and makes obvious effects on the distribution of the indicated efficiency. Therefore the combustion process is co-evolved with the intake process in a Miller cycle engine. The further improvement of brake specific fuel consumption is mainly limited by four factors, i.e., the back flow loss, the exergy loss, the incomplete expansion loss, and the combustion loss. The improvement of fuel consumption performance is at a cost of power performance, and the trade-off between the both essentially

  7. Willingness to pay for public health services in rural Central Java, Indonesia: methodological considerations when using the contingent valuation method.

    Science.gov (United States)

    Shono, Aiko; Kondo, Masahide; Ohmae, Hiroshi; Okubo, Ichiro

    2014-06-01

    In the health sectors of low- and middle-income countries, contingent valuation method (CVM) studies on willingness to pay (WTP) have been used to gather information on demand variation or financial perspectives alongside price setting, such as the introduction of user fees and valuation of quality improvements. However, WTP found in most CVM studies have only explored the preferences that consumers express through their WTP without exploring whether they are actually able to pay for it. Therefore, this study examines the issues pertaining to WTP estimation for health services using the conventional CVM. We conducted 202 household interviews in 2008, in which we asked respondents about three types of public health services in Indonesia and assessed WTP estimated by the conventional CVM as well as in the scenario of "resorting to debt" to recognize their budget constraints. We find that all the demand curves for both WTP scenarios show gaps. Furthermore, the gap for midwife services is negatively affected by household income and is larger for the poor. These results prove that CVM studies on WTP do not always reveal WTP in the latter scenario. Those findings suggest that WTP elicited by the conventional CVM is different to that from the maximum price that prevents respondents from resorting to debt as their WTP. In order to bridge this gap in the body of knowledge on this topic, studies should improve the scenarios that CVM analyses use to explore WTP. Furthermore, because valuing or pricing health services based on the results of CVM studies on WTP alone can exacerbate the inequity of access to these services, information provided by such studies requires careful interpretation when used for this purpose, especially for the poor and vulnerable sections of society. Copyright © 2014 Elsevier Ltd. All rights reserved.

  8. Coupled thermo-geophysical inversion for high-latitude permafrost monitoring - assessment of the method and practical considerations

    Science.gov (United States)

    Tomaskovicova, Sonia; Paamand, Eskild; Ingeman-Nielsen, Thomas; Bauer-Gottwein, Peter

    2013-04-01

    difference between the synthetic and the measured apparent resistivities is minimized in a least-squares inversion procedure by adjusting the thermal parameters of the heat model. A site-specific calibration is required since the relation between unfrozen water content and temperature is strongly dependent on the grain size of the soil. We present details of an automated permanent field measurement setup that has been established to collect the calibration data in Ilulissat, West Greenland. Considering the station location in high latitude environment, this setup is unique of its kind since the installation of automated geophysical stations in the Arctic conditions is a challenging task. The main issues are related to availability of adapted equipment, high demand on robustness of the equipment and method due to the harsh environment, remoteness of the field sites and related powering issues of such systems. By showing the results from the new-established geoelectrical station over the freezing period in autumn 2012, we prove the 2D time lapse resistivity tomography to be an effective method for permafrost monitoring in high latitudes. We demonstrate the effectivity of time lapse geoelectrical signal for petrophysical relationship calibration, which is enhanced comparing to sparse measurements.

  9. Green's function method with consideration of temperature dependent material properties for fatigue monitoring of nuclear power plants

    International Nuclear Information System (INIS)

    Koo, Gyeong-Hoi; Kwon, Jong-Jooh; Kim, Wanjae

    2009-01-01

    In this paper, a method to consider temperature dependent material properties when using the Green's function method is proposed by using a numerical weight function approach. This is verified by using detailed finite element analyses for a pressurizer spray nozzle with various assumed thermal transient load cases. From the results, it is found that the temperature dependent material properties can significantly affect the maximum peak stresses and the proposed method can resolve this problem with the weight function approach. Finally, it is concluded that the temperature dependency of the material properties affects the maximum stress ranges for a fatigue evaluation. Therefore, it is necessary to consider this effect to monitor fatigue damage when using a Green's function method for the real operating conditions in a nuclear power plant

  10. Implementation of the 3Rs (refinement, reduction, and replacement): validation and regulatory acceptance considerations for alternative toxicological test methods.

    Science.gov (United States)

    Schechtman, Leonard M

    2002-01-01

    Toxicological testing in the current regulatory environment is steeped in a history of using animals to answer questions about the safety of products to which humans are exposed. That history forms the basis for the testing strategies that have evolved to satisfy the needs of the regulatory bodies that render decisions that affect, for the most part, virtually all phases of premarket product development and evaluation and, to a lesser extent, postmarketing surveillance. Only relatively recently have the levels of awareness of, and responsiveness to, animal welfare issues reached current proportions. That paradigm shift, although sluggish, has nevertheless been progressive. New and alternative toxicological methods for hazard evaluation and risk assessment have now been adopted and are being viewed as a means to address those issues in a manner that considers humane treatment of animals yet maintains scientific credibility and preserves the goal of ensuring human safety. To facilitate this transition, regulatory agencies and regulated industry must work together toward improved approaches. They will need assurance that the methods will be reliable and the results comparable with, or better than, those derived from the current classical methods. That confidence will be a function of the scientific validation and resultant acceptance of any given method. In the United States, to fulfill this need, the Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM) and its operational center, the National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM), have been constituted as prescribed in federal law. Under this mandate, ICCVAM has developed a process and established criteria for the scientific validation and regulatory acceptance of new and alternative methods. The role of ICCVAM in the validation and acceptance process and the criteria instituted toward that end are described. Also

  11. Evaluation of the skin sensitizing potency of chemicals by using the existing methods and considerations of relevance for elicitation

    DEFF Research Database (Denmark)

    Basketter, David A; Andersen, Klaus E; Liden, Carola

    2005-01-01

    be translated into practical thresholds and whether these could be set for both induction and elicitation. Examples are given for substances falling into various potency groups for skin sensitization relating to results from the local lymph node assay, the guinea pig maximization test, the Buehler method...... products, cosmetics, food and feeding stuffs, which are subject to specific community legislation. The main questions that are answered in this report are whether it would be possible to give detailed guidance on how to grade allergen potency based on the existing methods, whether such grading could...

  12. 78 FR 52854 - Use of Differential Income Stream as an Application of the Income Method and as a Consideration...

    Science.gov (United States)

    2013-08-27

    ... some cases, the present value of an arm's length PCT Payment may be determined as the present value... present value of the differential income stream is consistent with reliable direct evidence of the... appropriate present value of the PCT Payment is $146 million. (ii) Based on the best method analysis described...

  13. Optimization and modeling of spot welding parameters with simultaneous multiple response consideration using multi objective Taguchi method and RSM

    Energy Technology Data Exchange (ETDEWEB)

    Muhammad, Nora Siah; Manurung Yupiter HP; Hafidzi, Moham Mad; Abas, Sun Haji Kiyai; Tham, Ghalib; Haru Man, Esa [Universiti Teknologi MARA (UiTM), Selangor (Malaysia)

    2012-08-15

    This paper presents an alternative method to optimize process parameters of resistance spot welding (RSW) towards weld zone development. The optimization approach attempts to consider simultaneously the multiple quality characteristics, namely weld nugget and heat affected zone (HAZ), using multi objective Taguchi method (MTM). The experimental study was conducted for plate thickness of 1.5mm under different welding current, weld time and hold time. The optimum welding parameters were investigated using the Taguchi method with L9 orthogonal array. The optimum value was analyzed by means of MTM, which involved the calculation of total normalized quality loss (TNQL) and multi signal to noise ratio (MSNR). A significant level of the welding parameters was further obtained by using analysis of variance (ANOVA). Furthermore, the first order model for predicting the weld zone development is derived by using response surface methodology (RSM). Based on the experimental confirmation test, the proposed method can be effectively applied to estimate the size of weld zone, which can be used to enhance and optimized the welding performance in RSW or other application.

  14. Optimization and modeling of spot welding parameters with simultaneous multiple response consideration using multi objective Taguchi method and RSM

    International Nuclear Information System (INIS)

    Muhammad, Nora Siah; Manurung Yupiter HP; Hafidzi, Moham Mad; Abas, Sun Haji Kiyai; Tham, Ghalib; Haru Man, Esa

    2012-01-01

    This paper presents an alternative method to optimize process parameters of resistance spot welding (RSW) towards weld zone development. The optimization approach attempts to consider simultaneously the multiple quality characteristics, namely weld nugget and heat affected zone (HAZ), using multi objective Taguchi method (MTM). The experimental study was conducted for plate thickness of 1.5mm under different welding current, weld time and hold time. The optimum welding parameters were investigated using the Taguchi method with L9 orthogonal array. The optimum value was analyzed by means of MTM, which involved the calculation of total normalized quality loss (TNQL) and multi signal to noise ratio (MSNR). A significant level of the welding parameters was further obtained by using analysis of variance (ANOVA). Furthermore, the first order model for predicting the weld zone development is derived by using response surface methodology (RSM). Based on the experimental confirmation test, the proposed method can be effectively applied to estimate the size of weld zone, which can be used to enhance and optimized the welding performance in RSW or other application

  15. A comparison of genotyping-by-sequencing analysis methods on low-coverage crop datasets shows advantages of a new workflow, GB-eaSy.

    Science.gov (United States)

    Wickland, Daniel P; Battu, Gopal; Hudson, Karen A; Diers, Brian W; Hudson, Matthew E

    2017-12-28

    Genotyping-by-sequencing (GBS), a method to identify genetic variants and quickly genotype samples, reduces genome complexity by using restriction enzymes to divide the genome into fragments whose ends are sequenced on short-read sequencing platforms. While cost-effective, this method produces extensive missing data and requires complex bioinformatics analysis. GBS is most commonly used on crop plant genomes, and because crop plants have highly variable ploidy and repeat content, the performance of GBS analysis software can vary by target organism. Here we focus our analysis on soybean, a polyploid crop with a highly duplicated genome, relatively little public GBS data and few dedicated tools. We compared the performance of five GBS pipelines using low-coverage Illumina sequence data from three soybean populations. To address issues identified with existing methods, we developed GB-eaSy, a GBS bioinformatics workflow that incorporates widely used genomics tools, parallelization and automation to increase the accuracy and accessibility of GBS data analysis. Compared to other GBS pipelines, GB-eaSy rapidly and accurately identified the greatest number of SNPs, with SNP calls closely concordant with whole-genome sequencing of selected lines. Across all five GBS analysis platforms, SNP calls showed unexpectedly low convergence but generally high accuracy, indicating that the workflows arrived at largely complementary sets of valid SNP calls on the low-coverage data analyzed. We show that GB-eaSy is approximately as good as, or better than, other leading software solutions in the accuracy, yield and missing data fraction of variant calling, as tested on low-coverage genomic data from soybean. It also performs well relative to other solutions in terms of the run time and disk space required. In addition, GB-eaSy is built from existing open-source, modular software packages that are regularly updated and commonly used, making it straightforward to install and maintain

  16. Theoretical considerations and a simple method for measuring alkalinity and acidity in low-pH waters by gran titration

    Science.gov (United States)

    Barringer, J.L.; Johnsson, P.A.

    1996-01-01

    Titrations for alkalinity and acidity using the technique described by Gran (1952, Determination of the equivalence point in potentiometric titrations, Part II: The Analyst, v. 77, p. 661-671) have been employed in the analysis of low-pH natural waters. This report includes a synopsis of the theory and calculations associated with Gran's technique and presents a simple and inexpensive method for performing alkalinity and acidity determinations. However, potential sources of error introduced by the chemical character of some waters may limit the utility of Gran's technique. Therefore, the cost- and time-efficient method for performing alkalinity and acidity determinations described in this report is useful for exploring the suitability of Gran's technique in studies of water chemistry.

  17. Considerations on the activity concentration determination method for low-level waste packages and nuclide data comparison between different countries

    International Nuclear Information System (INIS)

    Kashiwagi, M.; Mueller, W.

    2000-01-01

    In low-level waste disposal, acceptable activity concentration limits are regulated for individual nuclides and groups of nuclides according to the conditions of each disposal site. Such regulated limits principally concern total alpha and beta /gamma activity as well as nuclides such as C-14, Ni-63, and Pu-238 which are long-lived and difficult to measure (hereinafter referred to as difficult-to-measure nuclides). Before waste packages are transported to the disposal site, the activities or activity concentrations of the regulated nuclides and groups of nuclides in the waste packages must be assessed and declared. A generally applicable theoretical method to determine these activities is lacking at present. Therefore, to meet this requirement, for NPP waste each country independently samples actual waste and carries out radiochemical analyses on these samples. The activity concentrations of difficult-to-measure nuclides are then determined by statistical correlation of the measured data between difficult-to-measure nuclides and Co-60 and Cs-137 which are measurable from outside the waste packages (hereinafter referred to as key nuclides). This method is called 'Scaling Factor Method'. It is widely adopted as a method for determining the activity concentrations of the limited nuclides in low-level waste packages from NPP, and it is also approved by responsible authorities in the respective country. In the past, each country independently determined scaling factors based on measurements on samples from the local NPPs. In the first part of this study, the possibility of an international scaling factor assessment using a database integrating data from different countries was studied by comparing radiochemical analysis data between Germany, Japan, and the United States. These countries have accumulated a large number of those nuclide data required to determine scaling factors. Statistical values such as correlation coefficients change with an accumulation of data. In

  18. Non-invasive genetics outperforms morphological methods in faecal dietary analysis, revealing wild boar as a considerable conservation concern for ground-nesting birds.

    Science.gov (United States)

    Oja, Ragne; Soe, Egle; Valdmann, Harri; Saarma, Urmas

    2017-01-01

    Capercaillie (Tetrao urogallus) and other grouse species represent conservation concerns across Europe due to their negative abundance trends. In addition to habitat deterioration, predation is considered a major factor contributing to population declines. While the role of generalist predators on grouse predation is relatively well known, the impact of the omnivorous wild boar has remained elusive. We hypothesize that wild boar is an important predator of ground-nesting birds, but has been neglected as a bird predator because traditional morphological methods underestimate the proportion of birds in wild boar diet. To distinguish between different mammalian predator species, as well as different grouse prey species, we developed a molecular method based on the analysis of mitochondrial DNA that allows accurate species identification. We collected 109 wild boar faeces at protected capercaillie leks and surrounding areas and analysed bird consumption using genetic methods and classical morphological examination. Genetic analysis revealed that the proportion of birds in wild boar faeces was significantly higher (17.3%; 4.5×) than indicated by morphological examination (3.8%). Moreover, the genetic method allowed considerably more precise taxonomic identification of consumed birds compared to morphological analysis. Our results demonstrate: (i) the value of using genetic approaches in faecal dietary analysis due to their higher sensitivity, and (ii) that wild boar is an important predator of ground-nesting birds, deserving serious consideration in conservation planning for capercaillie and other grouse.

  19. Blame and guilt - a mixed methods study of obstetricians' and midwives' experiences and existential considerations after involvement in traumatic childbirth

    DEFF Research Database (Denmark)

    Schrøder, Katja; Jørgensen, Jan S; Lamont, Ronald F

    2016-01-01

    INTRODUCTION: When complications arise in the delivery room, midwives and obstetricians operate at the interface of life and death, and in rare cases the infant or the mother suffers severe and possibly fatal injuries related to the birth. This descriptive study investigated the numbers and propo......INTRODUCTION: When complications arise in the delivery room, midwives and obstetricians operate at the interface of life and death, and in rare cases the infant or the mother suffers severe and possibly fatal injuries related to the birth. This descriptive study investigated the numbers...... and proportions of obstetricians and midwives involved in such traumatic childbirth and explored their experiences with guilt, blame, shame and existential concerns. MATERIAL AND METHODS: A mixed methods study comprising a national survey of Danish obstetricians and midwives and a qualitative interview study...... the meaning of life. Sixty-five percent felt that they had become a better midwife or doctor due to the traumatic incident. CONCLUSIONS: The results of this large, exploratory study suggest that obstetricians and midwives struggle with issues of blame, guilt and existential concerns in the aftermath...

  20. Flaw acceptance criteria taking into consideration the NDT: radiographic and ultrasonic testing. Analysis through the fracture mechanics methods

    International Nuclear Information System (INIS)

    Capurro, E.; Alicino, F.; Corvi, A.

    1993-01-01

    The present study compares and evaluates the flaw acceptance criteria of the non-destructive inspections meeting European Community standards, through the application of the fracture mechanics methods that were determined and verified by the previous activity. Some choices were made; these, however, do not change the general validity of the conclusions. Shaved full-penetration butt welds of Class 1 components making up the primary circuit were considered and the following parameters varied: standards: French, German, Italian (ASME III) and UK; material: AISI 316 and low alloy steel A 533; base material and weld metal; temperature: RT, 370 deg C for the austenitic and 260 deg C for the ferritic steel; ultrasonic and radiographic methods; defect position: surface and internal; stress condition: situations with different primary and secondary stresses. From a preliminary examination of this study it is evident that the large quantity of results available and the abundance of information contained therein make a simple and exhaustive synthesis difficult. In fact, different analyses are possible and we have, therefore, limited the research to activities to perform a comparison and a general evaluation of the acceptance criteria of the non-destructive testing. (authors). 57 refs., 25 figs., 11 tabs

  1. CONSIDERATIONS ON APPLYING THE ANALYSIS MATRIX METHODS OF THE RISKS WITHIN THE AUDIT OF THE PROCUREMENT-PAYMENT CYCLE

    Directory of Open Access Journals (Sweden)

    Svetlana SLOBODEANU

    2014-07-01

    Full Text Available In the article hereby we analyse the matrix method of analysis of the risks for fraud and error at the level of the procurement-payments cycle. The risk of presentation of certain fraudulent information regarding the accounts of the procurement-payments cycle becomes more and more accentuated in the enhancement of the administration’s wish to present financial indicators of performance. In these conditions, the auditor is to necessarily quantify the involvement of this phenomenon for the report of audit. As a consequence, the auditor is to evaluate the risk for fraud and apply additional audit procedures for identifying all the possible indicators for „remaking” the financial situations on the side of the accounts of suppliers, activity, as a last consequence of which may be a qualified opinion on audit.

  2. Considerations in the rationale, design and methods of the Strategic Timing of AntiRetroviral Treatment (START) study

    Science.gov (United States)

    Babiker, Abdel G; Emery, Sean; Fätkenheuer, Gerd; Gordin, Fred M; Grund, Birgit; Lundgren, Jens D; Neaton, James D; Pett, Sarah L; Phillips, Andrew; Touloumi, Giota; Vjecha, Michael J

    2012-01-01

    Background Untreated human immunodeficiency virus (HIV) infection is characterized by progressive depletion of CD4+ T lymphocyte (CD4) count leading to the development of opportunistic diseases (acquired immunodeficiency syndrome (AIDS)), and more recent data suggest that HIV is also associated with an increased risk of serious non-AIDS (SNA) diseases including cardiovascular, renal, and liver diseases and non-AIDS-defining cancers. Although combination antiretroviral treatment (ART) has resulted in a substantial decrease in morbidity and mortality in persons with HIV infection, viral eradication is not feasible with currently available drugs. The optimal time to start ART for asymptomatic HIV infection is controversial and remains one of the key unanswered questions in the clinical management of HIV-infected individuals. Purpose In this article, we outline the rationale and methods of the Strategic Timing of AntiRetroviral Treatment (START) study, an ongoing multicenter international trial designed to assess the risks and benefits of initiating ART earlier than is currently practiced. We also describe some of the challenges encountered in the design and implementation of the study and how these challenges were addressed. Methods A total of 4000 study participants who are HIV type 1 (HIV-1) infected, ART naïve with CD4 count > 500 cells/μL are to be randomly allocated in a 1:1 ratio to start ART immediately (early ART) or defer treatment until CD4 count is AIDS, SNA, or death. The study had a pilot phase to establish feasibility of accrual, which was set as the enrollment of at least 900 participants in the first year. Results Challenges encountered in the design and implementation of the study included the limited amount of data on the risk of a major component of the primary endpoint (SNA) in the study population, changes in treatment guidelines when the pilot phase was well underway, and the complexities of conducting the trial in a geographically wide

  3. A simple method for analyzing exome sequencing data shows distinct levels of nonsynonymous variation for human immune and nervous system genes.

    Directory of Open Access Journals (Sweden)

    Jan Freudenberg

    Full Text Available To measure the strength of natural selection that acts upon single nucleotide variants (SNVs in a set of human genes, we calculate the ratio between nonsynonymous SNVs (nsSNVs per nonsynonymous site and synonymous SNVs (sSNVs per synonymous site. We transform this ratio with a respective factor f that corrects for the bias of synonymous sites towards transitions in the genetic code and different mutation rates for transitions and transversions. This method approximates the relative density of nsSNVs (rdnsv in comparison with the neutral expectation as inferred from the density of sSNVs. Using SNVs from a diploid genome and 200 exomes, we apply our method to immune system genes (ISGs, nervous system genes (NSGs, randomly sampled genes (RSGs, and gene ontology annotated genes. The estimate of rdnsv in an individual exome is around 20% for NSGs and 30-40% for ISGs and RSGs. This smaller rdnsv of NSGs indicates overall stronger purifying selection. To quantify the relative shift of nsSNVs towards rare variants, we next fit a linear regression model to the estimates of rdnsv over different SNV allele frequency bins. The obtained regression models show a negative slope for NSGs, ISGs and RSGs, supporting an influence of purifying selection on the frequency spectrum of segregating nsSNVs. The y-intercept of the model predicts rdnsv for an allele frequency close to 0. This parameter can be interpreted as the proportion of nonsynonymous sites where mutations are tolerated to segregate with an allele frequency notably greater than 0 in the population, given the performed normalization of the observed nsSNV to sSNV ratio. A smaller y-intercept is displayed by NSGs, indicating more nonsynonymous sites under strong negative selection. This predicts more monogenically inherited or de-novo mutation diseases that affect the nervous system.

  4. Study on Students' Impression Data in Practical Training Using Text Mining Method-Analysis of Considerable Communication.

    Science.gov (United States)

    Teramachi, Hitomi; Sugita, Ikuto; Ino, Yoko; Hayashi, Yuta; Yoshida, Aki; Otsubo, Manami; Ueno, Anri; Katsuno, Hayato; Noguchi, Yoshihiro; Iguchi, Kazuhiro; Tachi, Tomoya

    2017-09-01

    We analyzed impression data and the scale of communication skills of students using text mining method to clarify which area a student was conscious of in communication in practical training. The results revealed that students tended to be conscious of the difference between practical hospital training and practical pharmacy training. In practical hospital training, specific expressions denoting relationships were "patient-visit", "counseling-conduct", "patient-counseling", and "patient-talk". In practical pharmacy training, specific expressions denoting relationships were "patient counseling-conduct", "story-listen", "patient-many", and "patient-visit". In practical hospital training, the word "patient" was connected to many words suggesting that students were conscious of a patient-centered communication. In practical pharmacy training, words such as "patient counseling", "patient", and "explanation" were placed in center and connected with many other words and there was an independent relationship between "communication" and "accept". In conclusion, it was suggested that students attempted active patient-centered communication in practical hospital training, while they were conscious of listening closely in patient counseling in practical pharmacy training.

  5. Cell wall proteome of sugarcane stems: comparison of a destructive and a non-destructive extraction method showed differences in glycoside hydrolases and peroxidases.

    Science.gov (United States)

    Calderan-Rodrigues, Maria Juliana; Jamet, Elisabeth; Douché, Thibaut; Bonassi, Maria Beatriz Rodrigues; Cataldi, Thaís Regiani; Fonseca, Juliana Guimarães; San Clemente, Hélène; Pont-Lezica, Rafael; Labate, Carlos Alberto

    2016-01-11

    Sugarcane has been used as the main crop for ethanol production for more than 40 years in Brazil. Recently, the production of bioethanol from bagasse and straw, also called second generation (2G) ethanol, became a reality with the first commercial plants started in the USA and Brazil. However, the industrial processes still need to be improved to generate a low cost fuel. One possibility is the remodeling of cell walls, by means of genetic improvement or transgenesis, in order to make the bagasse more accessible to hydrolytic enzymes. We aimed at characterizing the cell wall proteome of young sugarcane culms, to identify proteins involved in cell wall biogenesis. Proteins were extracted from the cell walls of 2-month-old culms using two protocols, non-destructive by vacuum infiltration vs destructive. The proteins were identified by mass spectrometry and bioinformatics. A predicted signal peptide was found in 84 different proteins, called cell wall proteins (CWPs). As expected, the non-destructive method showed a lower percentage of proteins predicted to be intracellular than the destructive one (33% vs 44%). About 19% of CWPs were identified with both methods, whilst the infiltration protocol could lead to the identification of 75% more CWPs. In both cases, the most populated protein functional classes were those of proteins related to lipid metabolism and oxido-reductases. Curiously, a single glycoside hydrolase (GH) was identified using the non-destructive method whereas 10 GHs were found with the destructive one. Quantitative data analysis allowed the identification of the most abundant proteins. The results highlighted the importance of using different protocols to extract proteins from cell walls to expand the coverage of the cell wall proteome. Ten GHs were indicated as possible targets for further studies in order to obtain cell walls less recalcitrant to deconstruction. Therefore, this work contributed to two goals: enlarge the coverage of the sugarcane

  6. Increased component safety through improved methods for residual stress analysis. Subprojects. Consideration of the elastic-plastic material properties (phase 1). Final report

    International Nuclear Information System (INIS)

    Mirbach, David von

    2014-01-01

    Residual stresses in mechanical components can result in both detrimental but also beneficial effects on the strength and lifetime of the components. The most detailed knowledge of the residual stress state is of advantage or a pre-requisite for the assessment of the component performance. The mechanical methods for residual stress measurement are divided into the groups of non-destructive and destructive methods. Two commonly used mechanical methods for determination of residual stresses are the hole drilling method and the ring core method which can be regarded as semi-destructive methods. In the context of reactor safety research of the German Federal Ministry of Economic and Technology (BMWi) two fundamental and interacting weak points of the hole drilling method as well as of the ring core method, respectively, in order to determine residual stresses are going to be investigated. As a consequence reliability of the methods will be improved in this joint research project. On the one hand there are effects of geometrical boundary conditions of the components and on the other hand there is the influence of plasticity due to notch effects both affecting the released strain field after removing material and after all the calculated residual stresses. The first issue mentioned above is under the responsibility of the Institute of Materials Engineering (Kassel University) and the last one is investigated by Universitaet of Stuttgart-Otto-Graf-Institut - materials testing institute. As a consequence of a successful project the knowledge base will be considerably improved resulting in benefits for various engineering fields. Especially the quantitative consideration of real residual stress states for optimized component designs will be possible and after all the consequences of residual stresses on safety of components which are used in nuclear facilities can be evaluated. The state of art was reground in the first research chapter and the analysed strain gauges where

  7. Increased component safety through improved methods for residual stress analysis. Subprojects. Consideration of the elastic-plastic material properties (Phase 2). Final report

    International Nuclear Information System (INIS)

    Mirbach, David von

    2015-01-01

    Residual stresses in mechanical components can result in both detrimental but also beneficial effects on the strength and lifetime of the components. The most detailed knowledge of the residual stress state is of advantage or a pre-requisite for the assessment of the component performance. Two commonly used methods for determination of residual stresses are the hole drilling method and the ring core method which can be regarded to the mechanical methods. In the context of reactor safety research of the German Federal Ministry of Economic and Energy (BMWi) two fundamental and interacting weak points of the hole drilling method as well as of the ring core method, respectively, in order to determine residual stresses are going to be investigated. As a consequence reliability of the methods will be improved in this joint research project. On the one hand there are effects of geometrical boundary conditions of the components and on the other hand there is the influence of plasticity due to notch effects both affecting the released strain field after removing material and after all the calculated residual stresses. The first issue mentioned above is under the responsibility of the Institute of Materials Engineering (Kassel University) and the last one is investigated by materials testing institute university Stuttgart. As a consequence of a successful project the knowledge base will be considerably improved resulting in benefits for various engineering fields. Especially the quantitative consideration of real residual stress states for optimized component designs will be possible and after all the consequences of residual stresses on safety of components which are used in nuclear facilities can be evaluated. In this second experimental research chapter (phase 2) the findings of the first numerical and theoretical research chapter (phase 1) where proofed. The developed differential calculation method with the method of adaptive calibration functions were compared with the

  8. Climate considerations

    International Nuclear Information System (INIS)

    Hutchinson, I.P.G.; Ellison, R.D.

    1992-01-01

    The purpose of this paper is to investigate the conditions under which rainfall and snowmelt result in infiltration, percolation, and leachate formation, and to develop guidelines for incorporating these processes into the mine waste disposal regulations. This is important because in mine waste, and under certain circumstances, these processes can result in conditions which pose a threat to surface and ground water quality. This paper provides a general overview of infiltration, percolation, and leachate formation. It incorporates a discussion of the methods that can be used to quantify infiltration and the climatic and physical site and waste conditions under which percolation and leachate formation occur. Reference is made to case histories on infiltration, ground water recharge, and analytical procedures for calculating infiltration. An approach to infiltration prediction is outlined, and the paper concludes with a discussion on how climatic factors and prediction of infiltration could be incorporated into the regulations

  9. Fiscal considerations

    International Nuclear Information System (INIS)

    Wheeler, C.

    1992-01-01

    Most fiscal systems do not have provisions which adequately address the problems arising from the global nature of international oil and product trading. It is also difficult for the various tax authorities to keep abreast of the ever evolving hedging instruments. It is quite possible for an international trader or integrated oil company to find itself with losses which cannot match against profits either because of local tax rules or because the loss arises in one jurisdiction and profits in another. The corporate structuring and legal relationships of parties both within an organisation and outside can be key to mitigating effective double taxation and in assisting the production of reports to shareholders which show a fair picture of the group's activities. (author)

  10. Use of a novel cell adhesion method and digital measurement to show stimulus-dependent variation in somatic and oral ciliary beat frequency in Paramecium.

    Science.gov (United States)

    Bell, Wade E; Hallworth, Richard; Wyatt, Todd A; Sisson, Joseph H

    2015-01-01

    When Paramecium encounters positive stimuli, the membrane hyperpolarizes and ciliary beat frequency increases. We adapted an established immobilization protocol using a biological adhesive and a novel digital analysis system to quantify beat frequency in immobilized Paramecium. Cells showed low mortality and demonstrated beat frequencies consistent with previous studies. Chemoattractant molecules, reduction in external potassium, and posterior stimulation all increased somatic beat frequency. In all cases, the oral groove cilia maintained a higher beat frequency than mid-body cilia, but only oral cilia from cells stimulated with chemoattactants showed an increase from basal levels. © 2014 The Author(s) Journal of Eukaryotic Microbiology © 2014 International Society of Protistologists.

  11. Two-faces stationary irradiation method and dosimetric considerations for radiation processing at the multipurpose gamma irradiation facility / IPEN-CNEN

    International Nuclear Information System (INIS)

    Santos, Paulo S.; Vasquez, Pablo A.S.

    2015-01-01

    Over the last ten years, the Multipurpose Gamma Irradiation Facility of the Nuclear and Energy Research Institute - IPEN/CNEN located inside the Sao Paulo University campus has been providing services on radiation processing, especially for sterilization of health care and disposable medical products as well as support to research studies on modification of physical, chemical and biological properties of several materials. Placed at the same campus operates an extremely important radiopharmaceutical production facility when almost all disposable supplies used to produce medical products as the technetium-99m are continuously sterilized by gamma radiation. Many university biomedical research laboratories specially those working with equipment for cell cultures and vaccine production also make use of the gamma sterilization. Animal feed and shavings used by certified bioteries are routinely disinfected. Alternative underwater irradiation methods were developed to meet the demand of gemstone color enhancement. Human tissues including bone, skin, amniotic membranes, tendons, and cartilage belonging to National Banks are usually irradiated too. Different kind of polymers, hydrogels, foods as well native fruits, have been irradiated in this facility. Cultural heritage objects as books, paintings and furniture are disinfected routinely by gamma radiation. The success of the implementation of radiation processing in this facility is due to research and development of irradiation and dosimetry methods suitable for each condition. In this work are presented some considerations about the distribution dose and the two-faces stationary irradiation method developed and validated for this facility. (author)

  12. Two-faces stationary irradiation method and dosimetric considerations for radiation processing at the multipurpose gamma irradiation facility / IPEN-CNEN

    Energy Technology Data Exchange (ETDEWEB)

    Santos, Paulo S.; Vasquez, Pablo A.S., E-mail: psantos@ipen.br, E-mail: pavsalva@ipen.br [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2015-07-01

    Over the last ten years, the Multipurpose Gamma Irradiation Facility of the Nuclear and Energy Research Institute - IPEN/CNEN located inside the Sao Paulo University campus has been providing services on radiation processing, especially for sterilization of health care and disposable medical products as well as support to research studies on modification of physical, chemical and biological properties of several materials. Placed at the same campus operates an extremely important radiopharmaceutical production facility when almost all disposable supplies used to produce medical products as the technetium-99m are continuously sterilized by gamma radiation. Many university biomedical research laboratories specially those working with equipment for cell cultures and vaccine production also make use of the gamma sterilization. Animal feed and shavings used by certified bioteries are routinely disinfected. Alternative underwater irradiation methods were developed to meet the demand of gemstone color enhancement. Human tissues including bone, skin, amniotic membranes, tendons, and cartilage belonging to National Banks are usually irradiated too. Different kind of polymers, hydrogels, foods as well native fruits, have been irradiated in this facility. Cultural heritage objects as books, paintings and furniture are disinfected routinely by gamma radiation. The success of the implementation of radiation processing in this facility is due to research and development of irradiation and dosimetry methods suitable for each condition. In this work are presented some considerations about the distribution dose and the two-faces stationary irradiation method developed and validated for this facility. (author)

  13. Risk Aversion in Game Shows

    DEFF Research Database (Denmark)

    Andersen, Steffen; Harrison, Glenn W.; Lau, Morten I.

    2008-01-01

    We review the use of behavior from television game shows to infer risk attitudes. These shows provide evidence when contestants are making decisions over very large stakes, and in a replicated, structured way. Inferences are generally confounded by the subjective assessment of skill in some games......, and the dynamic nature of the task in most games. We consider the game shows Card Sharks, Jeopardy!, Lingo, and finally Deal Or No Deal. We provide a detailed case study of the analyses of Deal Or No Deal, since it is suitable for inference about risk attitudes and has attracted considerable attention....

  14. Preliminary considerations concerning actinide solubilities

    International Nuclear Information System (INIS)

    Newton, T.W.; Bayhurst, B.P.; Daniels, W.R.; Erdal, B.R.; Ogard, A.E.

    1980-01-01

    Work at the Los Alamos Scientific Laboratory on the fundamental solution chemistry of the actinides has thus far been confined to preliminary considerations of the problems involved in developing an understanding of the precipitation and dissolution behavior of actinide compounds under environmental conditions. Attempts have been made to calculate solubility as a function of Eh and pH using the appropriate thermodynamic data; results have been presented in terms of contour maps showing lines of constant solubility as a function of Eh and pH. Possible methods of control of the redox potential of rock-groundwater systems by the use of Eh buffers (redox couples) is presented

  15. Novel Method To Identify Source-Associated Phylogenetic Clustering Shows that Listeria monocytogenes Includes Niche-Adapted Clonal Groups with Distinct Ecological Preferences

    DEFF Research Database (Denmark)

    Nightingale, K. K.; Lyles, K.; Ayodele, M.

    2006-01-01

    population are identified (TreeStats test). Analysis of sequence data for 120 L. monocytogenes isolates revealed evidence of clustering between isolates from the same source, based on the phylogenies inferred from actA and inlA (P = 0.02 and P = 0.07, respectively; SourceCluster test). Overall, the Tree...... are biologically valid. Overall, our data show that (i) the SourceCluster and TreeStats tests can identify biologically meaningful source-associated phylogenetic clusters and (ii) L. monocytogenes includes clonal groups that have adapted to infect specific host species or colonize nonhost environments......., including humans, animals, and food. If the null hypothesis that the genetic distances for isolates within and between source populations are identical can be rejected (SourceCluster test), then particular clades in the phylogenetic tree with significant overrepresentation of sequences from a given source...

  16. Design Considerations for mHealth Programs Targeting Smokers Not Yet Ready to Quit: Results of a Sequential Mixed-Methods Study.

    Science.gov (United States)

    McClure, Jennifer B; Heffner, Jaimee; Hohl, Sarah; Klasnja, Predrag; Catz, Sheryl L

    2017-03-10

    Mobile health (mHealth) smoking cessation programs are typically designed for smokers who are ready to quit smoking. In contrast, most smokers want to quit someday but are not yet ready to quit. If mHealth apps were designed for these smokers, they could potentially encourage and assist more people to quit smoking. No prior studies have specifically examined the design considerations of mHealth apps targeting smokers who are not yet ready to quit. To inform the user-centered design of mHealth apps for smokers who were not yet ready to quit by assessing (1) whether these smokers were interested in using mHealth tools to change their smoking behavior; (2) their preferred features, functionality, and content of mHealth programs addressing smoking; and (3) considerations for marketing or distributing these programs to promote their uptake. We conducted a sequential exploratory, mixed-methods study. Qualitative interviews (phase 1, n=15) were completed with a demographically diverse group of smokers who were smartphone owners and wanted to quit smoking someday, but not yet. Findings informed a Web-based survey of smokers from across the United States (phase 2, n=116). Data were collected from April to September, 2016. Findings confirmed that although smokers not yet ready to quit are not actively seeking treatment or using cessation apps, most would be interested in using these programs to help them reduce or change their smoking behavior. Among phase 2 survey respondents, the app features, functions, and content rated most highly were (1) security of personal information; (2) the ability to track smoking, spending, and savings; (3) content that adaptively changes with one's needs; (4) the ability to request support as needed; (5) the ability to earn and redeem awards for program use; (6) guidance on how to quit smoking; and (7) content specifically addressing management of nicotine withdrawal, stress, depression, and anxiety. Results generally did not vary by stage of

  17. Reflexões sobre a anticoncepção na adolescência no Brasil Considerations on contraceptive methods used by adolescents in Brazil

    Directory of Open Access Journals (Sweden)

    Leila Maria Vieira

    2006-03-01

    Full Text Available Faz-se uma reflexão sobre a contracepção e suas conseqüências na adolescência, baseada em trabalhos nacionais e internacionais alertam para a precocidade do início da atividade sexual, a qual expõe os adolescentes aos riscos da gravidez e das doenças sexualmente transmissíveis e AIDS. Verifica-se que a maioria dos adolescentes recebe informações sobre contracepção, sendo a pílula e o preservativo os mais conhecidos e utilizados. Porém, registram-se elevada inadequação na utilização dos métodos contraceptivos, além da falta de serviços assistências, onde possam buscar orientações e atendimento. Tal realidade alerta para a necessidade de maior envolvimento de profissionais da saúde, da educação, família e comunidade, garantindo qualidade de vida aos adolescentes.Considerations about the consequences of contraceptives use by adolescents, are made, based on National and international studies warn against early sexual life exposing adolescents to the risks of pregnancy and sexualy transmissible diseases including AIDS. For the most adolescents informations on contraceptives are offered, the pill and the condom being the most popular and used methods. However, a high inadequacy level of contraceptive methods was determined in addition to the lack of guidance and assistance services. Such a situation alerts to the need to have health and education professionals, family and community involved to warrant adolescents an improved life quality.

  18. A method for realistic assessment of the environmental load following an accident in a nuclear facility taking into consideration measured values from environment monitoring

    International Nuclear Information System (INIS)

    Geiss, H.

    1985-01-01

    To enable consideration of time and space variations of source properties and of meteorological parameters, the quasi-stationary computational programme MUSEMET was developed for risk assessment. It was the modified for use in the prognosis of radiation exposure following accidents, in view of on-line registration of current meteorological data in 5- or 10-minute increments. By direct time-dependent continuous measurement of turbulence parameters a classification of diffusion categories is no more required. The diffusion parameters needed for this quasi-instationary Gaussian model are also determined continuously from turbulence measurements. MUSEMET and/or the follow-up programme MUSEDOS allow the determination of time- and location-dependent individual dose rates received by inhalation, γ- and β-submersion, γ-radiation from contaminated floors and by ingestion. An illustration is made in time-dependent form on a graphic display showing isodose lines together with a map of the site surroundings, or in tables. The anticipated values are continuously compared with the measured values from environment monitoring. γ-spectrometric measurements in particular can be exploited for calculations designed to enable accurate statements on the source, and the prognosis can be corrected accordingly. (orig./HP) [de

  19. Tokyo Motor Show 2003; Tokyo Motor Show 2003

    Energy Technology Data Exchange (ETDEWEB)

    Joly, E.

    2004-01-01

    The text which follows present the different techniques exposed during the 37. Tokyo Motor Show. The report points out the great tendencies of developments of the Japanese automobile industry. The hybrid electric-powered vehicles or those equipped with fuel cells have been highlighted by the Japanese manufacturers which allow considerable budgets in the research of less polluting vehicles. The exposed models, although being all different according to the manufacturer, use always a hybrid system: fuel cell/battery. The manufacturers have stressed too on the intelligent systems for navigation and safety as well as on the design and comfort. (O.M.)

  20. Show-Bix &

    DEFF Research Database (Denmark)

    2014-01-01

    The anti-reenactment 'Show-Bix &' consists of 5 dias projectors, a dial phone, quintophonic sound, and interactive elements. A responsive interface will enable the Dias projectors to show copies of original dias slides from the Show-Bix piece ”March på Stedet”, 265 images in total. The copies are...

  1. On the Use of Biomineral Oxygen Isotope Data to Identify Human Migrants in the Archaeological Record: Intra-Sample Variation, Statistical Methods and Geographical Considerations.

    Directory of Open Access Journals (Sweden)

    Emma Lightfoot

    Full Text Available Oxygen isotope analysis of archaeological skeletal remains is an increasingly popular tool to study past human migrations. It is based on the assumption that human body chemistry preserves the δ18O of precipitation in such a way as to be a useful technique for identifying migrants and, potentially, their homelands. In this study, the first such global survey, we draw on published human tooth enamel and bone bioapatite data to explore the validity of using oxygen isotope analyses to identify migrants in the archaeological record. We use human δ18O results to show that there are large variations in human oxygen isotope values within a population sample. This may relate to physiological factors influencing the preservation of the primary isotope signal, or due to human activities (such as brewing, boiling, stewing, differential access to water sources and so on causing variation in ingested water and food isotope values. We compare the number of outliers identified using various statistical methods. We determine that the most appropriate method for identifying migrants is dependent on the data but is likely to be the IQR or median absolute deviation from the median under most archaeological circumstances. Finally, through a spatial assessment of the dataset, we show that the degree of overlap in human isotope values from different locations across Europe is such that identifying individuals' homelands on the basis of oxygen isotope analysis alone is not possible for the regions analysed to date. Oxygen isotope analysis is a valid method for identifying first-generation migrants from an archaeological site when used appropriately, however it is difficult to identify migrants using statistical methods for a sample size of less than c. 25 individuals. In the absence of local previous analyses, each sample should be treated as an individual dataset and statistical techniques can be used to identify migrants, but in most cases pinpointing a specific

  2. Talking with TV shows

    DEFF Research Database (Denmark)

    Sandvik, Kjetil; Laursen, Ditte

    2014-01-01

    User interaction with radio and television programmes is not a new thing. However, with new cross-media production concepts such as X Factor and Voice, this is changing dramatically. The second-screen logic of these productions encourages viewers, along with TV’s traditional one-way communication...... mode, to communicate on interactive (dialogue-enabling) devices such as laptops, smartphones and tablets. Using the TV show Voice as our example, this article shows how the technological and situational set-up of the production invites viewers to engage in new ways of interaction and communication...

  3. Talk Show Science.

    Science.gov (United States)

    Moore, Mitzi Ruth

    1992-01-01

    Proposes having students perform skits in which they play the roles of the science concepts they are trying to understand. Provides the dialog for a skit in which hot and cold gas molecules are interviewed on a talk show to study how these properties affect wind, rain, and other weather phenomena. (MDH)

  4. Obesity in show cats.

    Science.gov (United States)

    Corbee, R J

    2014-12-01

    Obesity is an important disease with a high prevalence in cats. Because obesity is related to several other diseases, it is important to identify the population at risk. Several risk factors for obesity have been described in the literature. A higher incidence of obesity in certain cat breeds has been suggested. The aim of this study was to determine whether obesity occurs more often in certain breeds. The second aim was to relate the increased prevalence of obesity in certain breeds to the official standards of that breed. To this end, 268 cats of 22 different breeds investigated by determining their body condition score (BCS) on a nine-point scale by inspection and palpation, at two different cat shows. Overall, 45.5% of the show cats had a BCS > 5, and 4.5% of the show cats had a BCS > 7. There were significant differences between breeds, which could be related to the breed standards. Most overweight and obese cats were in the neutered group. It warrants firm discussions with breeders and cat show judges to come to different interpretations of the standards in order to prevent overweight conditions in certain breeds from being the standard of beauty. Neutering predisposes for obesity and requires early nutritional intervention to prevent obese conditions. Journal of Animal Physiology and Animal Nutrition © 2014 Blackwell Verlag GmbH.

  5. Honored Teacher Shows Commitment.

    Science.gov (United States)

    Ratte, Kathy

    1987-01-01

    Part of the acceptance speech of the 1985 National Council for the Social Studies Teacher of the Year, this article describes the censorship experience of this honored social studies teacher. The incident involved the showing of a videotape version of the feature film entitled "The Seduction of Joe Tynan." (JDH)

  6. Geophysical considerations of geothermics

    Energy Technology Data Exchange (ETDEWEB)

    Hayakawa, M

    1967-01-01

    The development and utilization of geothermal energy is described from the standpoint of geophysics. The internal temperature of the Earth and the history and composition of magmas are described. Methods of exploration such as gravity, magnetic, thermal and electrical surveys are discussed, as are geochemical and infrared photogrammetric techniques. Examples are provided of how these techniques have been used in Italy and at the Matsukawa geothermal field in Japan. Drilling considerations such as muds, casings and cementing materials are discussed. Solutions are proposed for problems of environmental pollution and plant expansion.

  7. A method for determination of X-ray elastic constants of materials showing non-linear sin2ψ diagrams and its application to Zn-Ni-alloy electroplate

    International Nuclear Information System (INIS)

    Sasaki, Toshihiko; Kuramoto, Makoto; Yoshioka, Yasuo.

    1990-01-01

    This paper describes the method and the experiment for the determination of the x-ray elastic constants of Zn-Ni-alloy electroplate. For this material, the sin 2 ψ method is not adequate to use because this material shows severely curved sin 2 ψ diagrams. Therefore, a new method developed by the authors was explained first. This new method is effective for materials showing nonlinear sin 2 ψ diagrams. Secondly, the experiment was made on the application of this method to the Zn-Ni-alloy electroplate. And it was found out that the experimental data agreed well to the theory of this method. As a result, the following values were obtained as the x-ray elastic constants of the sample measured: (1+ν)/E=8.44 TPa -1 ν/E=2.02 TPa -1 (author)

  8. The energy show

    International Nuclear Information System (INIS)

    1988-01-01

    The Energy Show is a new look at the problems of world energy, where our supplies come from, now and in the future. The programme looks at how we need energy to maintain our standards of living. Energy supply is shown as the complicated set of problems it is - that Fossil Fuels are both raw materials and energy sources, that some 'alternatives' so readily suggested as practical options are in reality a long way from being effective. (author)

  9. Showing Value (Editorial

    Directory of Open Access Journals (Sweden)

    Denise Koufogiannakis

    2009-06-01

    Full Text Available When Su Cleyle and I first decided to start Evidence Based Library and Information Practice, one of the things we agreed upon immediately was that the journal be open access. We knew that a major obstacle to librarians using the research literature was that they did not have access to the research literature. Although Su and I are both academic librarians who can access a wide variety of library and information literature from our institutions, we belong to a profession where not everyone has equal access to the research in our field. Without such access to our own body of literature, how can we ever hope for practitioners to use research evidence in their decision making? It would have been contradictory to the principles of evidence based library and information practice to do otherwise.One of the specific groups we thought could use such an open access venue for discovering research literature was school librarians. School librarians are often isolated and lacking access to the research literature that may help them prove to stakeholders the importance of their libraries and their role within schools. Certainly, school libraries have been in decline and the use of evidence to show value is needed. As Ken Haycock noted in his 2003 report, The Crisis in Canada’s School Libraries: The Case for Reform and Reinvestment, “Across the country, teacher-librarians are losing their jobs or being reassigned. Collections are becoming depleted owing to budget cuts. Some principals believe that in the age of the Internet and the classroom workstation, the school library is an artifact” (9. Within this context, school librarians are looking to our research literature for evidence of the impact that school library programs have on learning outcomes and student success. They are integrating that evidence into their practice, and reflecting upon what can be improved locally. They are focusing on students and showing the impact of school libraries and

  10. Design Considerations for mHealth Programs Targeting Smokers Not Yet Ready to Quit: Results of a Sequential Mixed-Methods Study

    OpenAIRE

    McClure, Jennifer B; Heffner, Jaimee; Hohl, Sarah; Klasnja, Predrag; Catz, Sheryl L

    2017-01-01

    Background Mobile health (mHealth) smoking cessation programs are typically designed for smokers who are ready to quit smoking. In contrast, most smokers want to quit someday but are not yet ready to quit. If mHealth apps were designed for these smokers, they could potentially encourage and assist more people to quit smoking. No prior studies have specifically examined the design considerations of mHealth apps targeting smokers who are not yet ready to quit. Objective To inform the user-cente...

  11. Choice of spatial resolution measurement methods to implement: considerations under a “New Laboratory”-scenario for imaging optical testing and research

    CSIR Research Space (South Africa)

    Theron, B

    2013-04-01

    Full Text Available A key imaging quality metric for an optical system (e.g. a camera or surveillance device) is its resolution. Methods to measure this, range from visual observation methods on resolution target charts, through more rigorous characterization, e...

  12. The determination of the pore distribution and the consideration of methods leading to the prediction of retention characteristics of membrane filters

    International Nuclear Information System (INIS)

    Badenhop, C.T.

    1983-01-01

    Presented here is a method for the determination of the pore size distribution of a membrane microfilter. Existing test metods are either cumbersome, as is the Erbe method; time consuming, as is the evaluation of electron microscope photographs; do not really measure the pore distribution, as the mercury intrusion method; or do not satisfactorily evaluate the large pore range of the filter, as is the case with the automated ASTM method. The new method described in this paper is based upon the solution of the integral flow equation for the pore distribution function. A computer program evaluates the flow test data and calculates the numerical pore distribution, water-flow distribution, air-flow distribution and capillary area distribution, as a function of the pore size. (orig./RW)

  13. Considerations for expanding community exercise programs incorporating a healthcare-recreation partnership for people with balance and mobility limitations: a mixed methods evaluation.

    Science.gov (United States)

    Salbach, Nancy M; Howe, Jo-Anne; Baldry, Diem; Merali, Saira; Munce, Sarah E P

    2018-04-02

    To increase access to safe and appropriate exercise for people with balance and mobility limitations, community organizations have partnered with healthcare providers to deliver an evidence-based, task-oriented group exercise program in community centers in Canada. We aimed to understand challenges and solutions to implementing this program model to inform plans for expansion. At a 1-day meeting, 53 stakeholders (healthcare/recreation personnel, program participants/caregivers, researchers) identified challenges to program implementation that were captured by seven themes: Resources to deliver the exercise class (e.g., difficulty finding instructors with the skills to work with people with mobility limitations); Program marketing (e.g., to foster healthcare referrals); Transportation (e.g., particularly from rural areas); Program access (e.g., program full); Maintaining program integrity; Sustaining partnerships (i.e., with healthcare partners); and Funding (e.g., to deliver program or register). Stakeholders prioritized solutions to form an action plan. A survey of individuals supervising 28 programs revealed that people with stroke, acquired brain injury, multiple sclerosis, and Parkinson's disease register at 95-100% of centers. The most prevalent issues with program fidelity across centers were not requiring a minimum level of walking ability (32%), class sizes exceeding 12 (21%), and instructor-to-participant ratios exceeding 1:4 (19%). Findings provide considerations for program expansion.

  14. An investigation of sugar extraction methods and the use of microwave power for date syrup processing: efficiency and color related considerations.

    Science.gov (United States)

    Fennir, M A; Landry, J A; Ramaswamy, H S; Raghavan, V G S

    2003-01-01

    This study investigates the effect of extraction methods on the color of date syrup and the potential use of microwave power for syrup processing. Sugar solutions were extracted from dates by boiling, soaking and blending. Color and sugar content of the extracted solutions were measured, and the percentage of sugar extracted form the total fruit sugar determined. Boiling was found to be the most efficient method of extraction whereby 74% of total samples sugar was extracted. In contrast, only 54.2% of fruit sugar was extracted by blending and 42% by soaking. In addition, solutions extracted by soaking and blending had a foaming problem in the subsequent concentration process. The extraction method had no effect on the product final color. The extracted solution was concentrated using two heating methods: conventional and microwave heating at a 600 W capacity and a frequency of 2450 MHz applied at three power levels: 10, 7, and 6. In the heating process, 180 minutes were needed to achieve a 77% degrees Brix using convective heating, while it took 81, 138, and 166 minutes of microwave heating at power level 10, 7, and 6, respectively to achieve the same concentration. Water activity of the syrup was measured within a sugar content range of 50 to 80% degrees Brix and the sugar concentration at which the product is shelf stable was determined at 76%.

  15. Practical stress evaluation method of RC slab for bending moment in consideration of additional in-plane stress caused by boundary condition

    International Nuclear Information System (INIS)

    Kobayashi, Toshio; Adachi, Naohito; Masuda, Kiyoshi

    1998-01-01

    In a design of a thick RC slab such as a basemat of a nuclear reactor building, the design method as same as for RC column is usually used. In this method, bending moment and axial force which are obtained by linear Finite Element Method (FEM) for external force are considered. But the assumption for linear FEM in which concrete participates for tensile stress is different from that for reinforcement design in which concrete does not participate for tensile stress. This difference of the assumption results that in-plane tensile strain at the center of the slab depth in the reinforcement design is larger than that in linear FEM. Some effects will appear in stress distribution if this tensile strain is constrained by boundary condition. In this paper, a practical method to evaluate the boundary constrain effects for this in-plane tensile strain is proposed and a simulation analysis of a thick reinforced concrete slab with a large opening for out-of-plane force is also reported. (author)

  16. Nuclear energy applications - ethical considerations

    International Nuclear Information System (INIS)

    Hoermann, K.

    1980-01-01

    Following an Austrian referendum in 1978 which showed a small majority against operation of nuclear power stations, the economic penalties involved by this decision are qualitatively discussed, with emphasis on reduced standards of living. Religious considerations are examined and the difficulty of obtaining informed public opinion is stressed. Alternative sources of energy, including nuclear fusion, are briefly referred to. (G.M.E.)

  17. Characterization of pigment/binder - systems in arts via FTIR and UV/Vis/NIR - spectroscopy with special consideration of nondestructive methods

    International Nuclear Information System (INIS)

    Vetter, W.A.

    2014-01-01

    The main focus of this doctoral thesis is on the non-destructive analysis of art objects by using compound specific reflection-UV/Vis/NIR and reflection-FTIR spectroscopy. Based on commercially available instruments, measuring systems have been designed and built to meet the specific requirements of material analysis in the field of art. These systems have been utilized to analyse different types of art objects (watercolour paintings, easel paintings, contemporary graphic art objects) in order to identify the materials used by the artists. Furthermore, two new procedures are presented which allow to build up adequate reference databases from only minimal sample amounts of original watercolour materials of the 19th century. This is a crucial point as both methods require references for the identification of the materials. The results obtained demonstrate that UV/Vis/NIR and FTIR spectroscopy in reflection mode enable the non-destructive identification of a variety of both, organic and inorganic materials, particularly in combination with element specific XRF (X-ray fluorescence analysis) and thus are valuable tools for the analysis of cultural heritage objects. Furthermore, the results have shown that a comparison of the complementary methods strongly facilitated the evaluation of spectra obtained by the particular analytical techniques and hence reliable results could be obtained in many cases. As expected, several frequently used pigments e.g. carbon based blacks, earth pigments and lake pigments could not be identified unambiguously due to methodical limitations. Therefore, the use of additional complementary methods such as Raman spectroscopy and X-ray diffraction (XRD) would be highly desirable. Except a few examples, the characteristics of the radiation used for the investigations did not allow to draw conclusions about the distribution of materials in multilayer structures. For this reason, it still remains necessary to analyse cross-sections of samples for a

  18. First data on canids depredation on livestock in an area of recent recolonization by wolf in central Italy : considerations on conflict survey and prevention methods

    Directory of Open Access Journals (Sweden)

    Magrini Caterina

    2014-03-01

    Full Text Available Wolf and dog depredation on livestock in the province of Rieti, central Italy, in 2007-2008, was studied. The study area was characterized by a high degree of human disturbance, widespread presence of free ranging dogs and a recent wolf recolonization. Because of the ineffectiveness of compensation programmes, it was not possible to use the official statistics to investigate the extent of the conflict, but sample interviews and surveys of farmers were used. Also, the farming protection tecniques adopted for different livestock species were analysed; the most utilized husbandry method was stabling for cattle and pigs, annual fenced grazing for horses and sheeps, and annual open grazing only for goats. Although sheep farms were the most attacked because of their availability (33.6% of the whole farms, goat farms were the most selected by predators because of their accessibility (40% of farms kept goats in annual open grazing. Management implications to mitigate livestock depredation were discussed.

  19. SU-E-T-670: Radiotherapy Vault Shielding Evaluation Method for a Flattening Filter-Free (FFF) Linac-Practical Considerations and Recommendations

    Energy Technology Data Exchange (ETDEWEB)

    Mihailidis, D [CAMC Cancer Center-Alliance Oncology and West Virginia University, Charleston, WV (United States)

    2015-06-15

    Purpose: To date, there isn’t formal approach for flattening filter-free (FFF) linac vault shielding evaluation, thus, we propose an extension to NCRP#151 to accommodate the recent large number of FFF linac installations.Methods and Materials: We extended the approach in NCRP#151 to design two Truebeam vaults in our new cancer center for hypofractionated treatments. Monte Carlo calculations have characterized primary, scattered, leakage and neutron radiations from FFF-modes. These calculations have shown that: a) FFF primary beam is softer on the central-axis compared to flattening filtered (FF), b) the lateral dose profile is peaked on the central axis and less integral target current is required to generate the same tumor dose with the FF beam. Thus, the TVLs for FFF mode are smaller than those of the FF mode and the scatter functions of the FF mode (NCRP#151) may not be appropriate for FFF-mode, c) the neutron source strength and fluence for 18X-FFF is smaller than 18X-FF, but it is not of a concern here, no 18X-FFF-mode is available on the linac under investigation. Results: These barrier thickness are smaller (12% reduction on the average) than those computed for conventional FF mode with same realistic primary workload since, the primary TVLs used here are smaller and the WL is smaller than the conventional (almost half reduced), keeping the TADR in tolerance. Conclusions: A comprehensive method for shielding barrier calculations based on dedicated data for FFF-mode linacs is highly desired. Meanwhile, we provide an extension to NCRP#151 to accommodate the shielding design of such installations. It is also shown that if a vault is already designed for IMRT/VMAT and SABR hypofractionated treatments with FFF-mode linac, the vault can also be used for a FFF mode linac replacement, leaving some leeway for slightly higher workload on the FFF linac.

  20. SU-E-T-670: Radiotherapy Vault Shielding Evaluation Method for a Flattening Filter-Free (FFF) Linac-Practical Considerations and Recommendations

    International Nuclear Information System (INIS)

    Mihailidis, D

    2015-01-01

    Purpose: To date, there isn’t formal approach for flattening filter-free (FFF) linac vault shielding evaluation, thus, we propose an extension to NCRP#151 to accommodate the recent large number of FFF linac installations.Methods and Materials: We extended the approach in NCRP#151 to design two Truebeam vaults in our new cancer center for hypofractionated treatments. Monte Carlo calculations have characterized primary, scattered, leakage and neutron radiations from FFF-modes. These calculations have shown that: a) FFF primary beam is softer on the central-axis compared to flattening filtered (FF), b) the lateral dose profile is peaked on the central axis and less integral target current is required to generate the same tumor dose with the FF beam. Thus, the TVLs for FFF mode are smaller than those of the FF mode and the scatter functions of the FF mode (NCRP#151) may not be appropriate for FFF-mode, c) the neutron source strength and fluence for 18X-FFF is smaller than 18X-FF, but it is not of a concern here, no 18X-FFF-mode is available on the linac under investigation. Results: These barrier thickness are smaller (12% reduction on the average) than those computed for conventional FF mode with same realistic primary workload since, the primary TVLs used here are smaller and the WL is smaller than the conventional (almost half reduced), keeping the TADR in tolerance. Conclusions: A comprehensive method for shielding barrier calculations based on dedicated data for FFF-mode linacs is highly desired. Meanwhile, we provide an extension to NCRP#151 to accommodate the shielding design of such installations. It is also shown that if a vault is already designed for IMRT/VMAT and SABR hypofractionated treatments with FFF-mode linac, the vault can also be used for a FFF mode linac replacement, leaving some leeway for slightly higher workload on the FFF linac

  1. Risk considerations for a long-term open-state of the radioactive waste storage facility Schacht Asse II. Variation of the parameter sets for radio-ecological modeling using the Monte Carlo method

    International Nuclear Information System (INIS)

    Kueppers, Christian; Ustohalova, Veronika

    2013-01-01

    The risk considerations for a long-term open-state of the radioactive waste storage facility Schacht Asse II include the following issues: description of radio-ecological models for the radionuclide transport in the covering rock formations and determination of the radiation exposure, parameters of the radio-ecological and their variability, Monte-Carlo method application. The results of the modeling calculations include the group short-living radionuclides, long-living radionuclides, radionuclides in the frame of decay chains and sensitivity analyses with respect to the correlation of input data and results.

  2. Dose gradient analyses in linac-based intracranial stereotactic radiosurgery using paddick's gradient index. Consideration of the optimal method for plan evaluation

    International Nuclear Information System (INIS)

    Ohtakara, Kazuhiro; Hayashi, Shinya; Hoshi, Hiroaki

    2011-01-01

    The objective of our study was to describe the dose gradient characteristics of Linac-based stereotactic radiosurgery using Paddick's gradient index (GI) and to elucidate the factors influencing the GI value. Seventy-three plans for brain metastases using the dynamic conformal arcs were reviewed. The GI values were calculated at the 80% and 90% isodose surfaces (IDSs) and at the different target coverage IDSs (D99, D95, D90, and D85). The GI values significantly decreased as the target coverage of the reference IDS increased (the percentage of the IDS decreased). There was a significant inverse correlation between the GI values and target volume. The plans generated with the addition of a 1-mm leaf margin had worse GI values both at the D99 and D95 relative to those without leaf margin. The number and arrangement of arcs also affected the GI value. The GI values are highly sensitive to the IDS selection variability for dose prescription or evaluation, the target volume, and the planning method. To objectively compare the quality of dose gradient between rival plans, it would be preferable to employ the GI defined at the reference IDS indicating the specific target coverage (exempli gratia (e.g.), D95), irrespective of the intended marginal dose. The modified GI (mGI), defined in this study, substituting the denominator of the original GI with the target volume, would be useful to compensate for the false superior GI value in cases of target over-coverage with the reference IDS and to objectively evaluate the dose gradient outside the target boundary. (author)

  3. DOE handbook: Design considerations

    International Nuclear Information System (INIS)

    1999-04-01

    The Design Considerations Handbook includes information and suggestions for the design of systems typical to nuclear facilities, information specific to various types of special facilities, and information useful to various design disciplines. The handbook is presented in two parts. Part 1, which addresses design considerations, includes two sections. The first addresses the design of systems typically used in nuclear facilities to control radiation or radioactive materials. Specifically, this part addresses the design of confinement systems and radiation protection and effluent monitoring systems. The second section of Part 1 addresses the design of special facilities (i.e., specific types of nonreactor nuclear facilities). The specific design considerations provided in this section were developed from review of DOE 6430.1A and are supplemented with specific suggestions and considerations from designers with experience designing and operating such facilities. Part 2 of the Design Considerations Handbook describes good practices and design principles that should be considered in specific design disciplines, such as mechanical systems and electrical systems. These good practices are based on specific experiences in the design of nuclear facilities by design engineers with related experience. This part of the Design Considerations Handbook contains five sections, each of which applies to a particular engineering discipline

  4. DOE handbook: Design considerations

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-04-01

    The Design Considerations Handbook includes information and suggestions for the design of systems typical to nuclear facilities, information specific to various types of special facilities, and information useful to various design disciplines. The handbook is presented in two parts. Part 1, which addresses design considerations, includes two sections. The first addresses the design of systems typically used in nuclear facilities to control radiation or radioactive materials. Specifically, this part addresses the design of confinement systems and radiation protection and effluent monitoring systems. The second section of Part 1 addresses the design of special facilities (i.e., specific types of nonreactor nuclear facilities). The specific design considerations provided in this section were developed from review of DOE 6430.1A and are supplemented with specific suggestions and considerations from designers with experience designing and operating such facilities. Part 2 of the Design Considerations Handbook describes good practices and design principles that should be considered in specific design disciplines, such as mechanical systems and electrical systems. These good practices are based on specific experiences in the design of nuclear facilities by design engineers with related experience. This part of the Design Considerations Handbook contains five sections, each of which applies to a particular engineering discipline.

  5. Increased component safety through improved methods for residual stress analysis. Subprojects. Consideration of real component geometries (phase 2). Final report; Erhoehung der Komponentensicherheit durch verbesserte Verfahren zur Eigenspannungsanalyse. Teilvorhaben. Beruecksichtigung realer Komponentengeometrien (Phase 2). Abschlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    Scholtes, B.; Nau, Andreas

    2015-06-01

    Residual stresses can be result in both detrimental as well as beneficial consequences on the component's strength and lifetime. A most detailed knowledge of the residual stress state is a pre-requisite for the assessment of the component's performance. The mechanical methods for residual stress measurements are classified in non-destructive, destructive and semi-destructive methods. The two commonly used (semi-destructive) mechanical methods are the hole drilling and the ring core method. In the context of reactor safety research of the Federal Ministry of Economic Affairs and Energy (BMWi), two fundamental and interacting weak points of the hole drilling as well as ofthe ring core method are investigated. On the one hand, there are effects concerning geometricalboundary conditions of the components and on the other hand, there are influences of plasticity due to notch effects. Both aspects affect the released strain field, when the material is removed and finally, the calculated residual stresses. The first issue mentioned above is under the responsibility of Institute of Materials Engineering - Metallic Materials (KasselUniversity) and the last one will be investigated by University of Stuttgart-Otto-Graf-Institut - materials testing institute. As a consequence of a successful project, the present knowledgebase will be considerably improved and will be available for various engineering fields. Especially,the quantitative consideration of real residual stress states for optimized component designs will be feasible and finally the consequences of residual stresses on the component's safety, which are used in nuclear facilities, can be evaluated. The findings of the application-oriented research period (phase 2) at Kassel University are documented in this report.

  6. Technical specification improvement through safety margin considerations

    International Nuclear Information System (INIS)

    Howard, R.C.; Jansen, R.L.

    1986-01-01

    Westinghouse has developed an approach for utilizing safety analysis margin considerations to improve plant operability through technical specification revision. This approach relies on the identification and use of parameter interrelations and sensitivities to identify acceptable operating envelopes. This paper summarizes technical specification activities to date and presents the use of safety margin considerations as another viable method to obtain technical specification improvement

  7. Modeling Unobserved Consideration Sets for Household Panel Data

    NARCIS (Netherlands)

    J.E.M. van Nierop; R. Paap (Richard); B. Bronnenberg; Ph.H.B.F. Franses (Philip Hans)

    2000-01-01

    textabstractWe propose a new method to model consumers' consideration and choice processes. We develop a parsimonious probit type model for consideration and a multinomial probit model for choice, given consideration. Unlike earlier models of consideration ours is not prone to the curse of

  8. Engineering radioecology: Methodological considerations

    International Nuclear Information System (INIS)

    Nechaev, A.F.; Projaev, V.V.; Sobolev, I.A.; Dmitriev, S.A.

    1995-01-01

    The term ''radioecology'' has been widely recognized in scientific and technical societies. At the same time, this scientific school (radioecology) does not have a precise/generally acknowledged structure, unified methodical basis, fixed subjects of investigation, etc. In other words, radioecology is a vast, important but rather amorphous conglomerate of various ideas, amalgamated mostly by their involvement in biospheric effects of ionizing radiation and some conceptual stereotypes. This paradox was acceptable up to a certain time. However, with the termination of the Cold War and because of remarkable political changes in the world, it has become possible to convert the problem of environmental restoration from the scientific sphere in particularly practical terms. Already the first steps clearly showed an imperfection of existing technologies, managerial and regulatory schemes; lack of qualified specialists, relevant methods and techniques; uncertainties in methodology of decision-making, etc. Thus, building up (or maybe, structuring) of special scientific and technological basis, which the authors call ''engineering radioecology'', seems to be an important task. In this paper they endeavored to substantiate the last thesis and to suggest some preliminary ideas concerning the subject matter of engineering radioecology

  9. Health physics considerations in decontamination and decommissioning

    International Nuclear Information System (INIS)

    1985-12-01

    These proceedings contain papers on legal considerations, environmental aspects, decommissioning equipment and methods, instrumentation, applied health physics, waste classification and disposal, and project experience. Separate abstracts have been prepared for individual papers

  10. High-frequency parameters of magnetic films showing magnetization dispersion

    International Nuclear Information System (INIS)

    Sidorenkov, V.V.; Zimin, A.B.; Kornev, Yu.V.

    1988-01-01

    Magnetization dispersion leads to skewed resonance curves shifted towards higher magnetizing fields, together with considerable reduction in the resonant absorption, while the FMR line width is considerably increased. These effects increase considerably with frequency, in contrast to films showing magnetic-anisotropy dispersion, where they decrease. It is concluded that there may be anomalies in the frequency dependence of the resonance parameters for polycrystalline magnetic films

  11. Entrepreneurship: Some Considerations

    Directory of Open Access Journals (Sweden)

    V. Martinho

    2016-02-01

    Full Text Available In this work it is presented some considerations about entrepreneurship. Most of these questions are linked with Portuguese context. Portugal has some particularities, namely because the asymmetries between the littoral and the interior. This situation carried out some problems that complicate and prevent the appearance of new innovated business. In a situation of crisis like that we have today this context can become a really problem to solve some questions.

  12. Fusion facility siting considerations

    International Nuclear Information System (INIS)

    Bussell, G.T.

    1985-01-01

    Inherent in the fusion program's transition from hydrogen devices to commercial power machines is a general increase in the size and scope of succeeding projects. This growth will lead to increased emphasis on safety, environmental impact, and the external effects of fusion in general, and of each new device in particular. A critically important consideration in this regard is site selection. The purpose of this paper is to examine major siting issues that may affect the economics, safety, and environmental impact of fusion

  13. Opinions among Danish knee surgeons about indications to perform total knee replacement showed considerable variation

    DEFF Research Database (Denmark)

    Troelsen, Anders; Schrøder, Henrik; Husted, Henrik

    2012-01-01

    During the past decade, the incidence of primary total knee replacement (TKA) surgery in Denmark has approximately doubled. This increase could be due to weakened indications to perform TKA surgery. We aimed to investigate variation in opinions about indications to perform TKA among Danish knee...

  14. Familienfreundliche Betriebe nehmen auf Vaterschaft Rücksicht! Family-Friendly Businesses Show Consideration for Fatherhood!

    Directory of Open Access Journals (Sweden)

    Martin R. Textor

    2004-11-01

    Full Text Available Das Handbuch VäterArbeit zeigt auf, wie wichtig es ist, das Thema „Vatersein“ in Unternehmen und Organisationen zu diskutieren und betriebliche Maßnahmen zur Unterstützung einer kindgerechten Ausübung von Vaterschaft zu initiieren und umzusetzen. Die Politik muss dafür die entsprechenden gesetzlichen Rahmenbedingungen schaffen. Väter sollten ihre Rollen hinterfragen und die schon gegebenen Spielräume hinsichtlich einer verbesserten Vereinbarkeit von Familie und Beruf nutzen.Handbuch VaterArbeit (The CareerFather Handbook illustrates how important it is to discuss the subject of “being a father” in businesses and organizations and to initiate and apply company measures to promote a practice of fatherhood that is equitable to the child. Policy must establish the corresponding legal framework and conditions for this. Fathers should question their roles and utilize the latitude already present that promotes an improved agreement between family and job.

  15. Storage array reflection considerations

    International Nuclear Information System (INIS)

    Haire, M.J.; Jordan, W.C.; Taylor, R.G.

    1997-01-01

    The assumptions used for reflection conditions of single containers are fairly well established and consistently applied throughout the industry in nuclear criticality safety evaluations. Containers are usually considered to be either fully water reflected (i.e., surrounded by 6 to 12 in. of water) for safety calculations or reflected by 1 in. of water for nominal (structural material and air) conditions. Tables and figures are usually available for performing comparative evaluations of containers under various loading conditions. Reflection considerations used for evaluating the safety of storage arrays of fissile material are not as well established. When evaluating arrays, it has become more common for analysts to use calculations to demonstrate the safety of the array configuration. In performing these calculations, the analyst has considerable freedom concerning the assumptions made for modeling the reflection of the array. Considerations are given for the physical layout of the array with little or no discussion (or demonstration) of what conditions are bounded by the assumed reflection conditions. For example, an array may be generically evaluated by placing it in a corner of a room in which the opposing walls are far away. Typically, it is believed that complete flooding of the room is incredible, so the array is evaluated for various levels of water mist interspersed among array containers. This paper discusses some assumptions that are made regarding storage array reflection

  16. Part 8. Deployment considerations

    International Nuclear Information System (INIS)

    Dance, K.D.; Chang, Y.I.; Daly, T.A.

    1980-01-01

    This report addresses considerations of fast breeder reactor development and deployment from a national perspective. Nations vary greatly in their expertise and interest relative to nuclear power, and hence a single set of steps to be taken by a nation in decision-making on breeder development and deployment cannot be presented. The approach taken in this report is to present discussions on key factors influencing the breeder development and deployment decisions, especially in non-breeder nations, by drawing upon historical perspectives of the Light Water Reactor for comparison

  17. Storage array reflection considerations

    International Nuclear Information System (INIS)

    Haire, M.J.; Jordan, W.C.; Taylor, R.G.

    1997-01-01

    The assumptions used for reflection conditions of single containers are fairly well established and consistently applied throughout the industry in nuclear criticality safety evaluations. Containers are usually considered to be either fully water-reflected (i.e. surrounded by 6 to 12 in. of water) for safety calculations or reflected by 1 in. of water for nominal (structural material and air) conditions. Tables and figures are usually available for performing comparative evaluations of containers under various loading conditions. Reflection considerations used for evaluating the safety of storage arrays of fissile material are not as well established

  18. Measuring performance at trade shows

    DEFF Research Database (Denmark)

    Hansen, Kåre

    2004-01-01

    Trade shows is an increasingly important marketing activity to many companies, but current measures of trade show performance do not adequately capture dimensions important to exhibitors. Based on the marketing literature's outcome and behavior-based control system taxonomy, a model is built...... that captures a outcome-based sales dimension and four behavior-based dimensions (i.e. information-gathering, relationship building, image building, and motivation activities). A 16-item instrument is developed for assessing exhibitors perceptions of their trade show performance. The paper presents evidence...

  19. Ideological Considerations in Official Dubbing in Iran

    Directory of Open Access Journals (Sweden)

    Masood Khoshsaligheh

    2016-02-01

    Full Text Available In our globalizing world, audiovisual products are understandably considered tools that advertise their original language and culture. Most societies do not stand any interference from the outside, especially if it considerably opposes the socio-cultural norms. Translation is a practice of cross-cultural communication which most often complies with the socio-cultural guidelines and norms of the recipient society. However, translated products might face resistance as they can be regarded threatening and hostile by the ruling gatekeepers. Given the dramatic disparities between most languages and cultures, translators are not the only decision-makers and other agents have pivotal roles in the process of adapting the translated product to the dominant conventions and socio-cultural norms. This paper aims at shedding some light on the role which agents play in the process of dubbing, both for public access national television and for private home distribution. The study explores the effects of preliminary and operational norms, and cultural appropriation conducted at both textual and visual levels through a method including interview data and textual analysis. The results show that foreign movies dubbed into Persian in the religious context of the contemporary Iran are strictly controlled both before the process of dubbing and during and after the process of dubbing due to a number of socio-cultural, political, and ideological considerations.

  20. Increased component safety through improved methods for residual stress analysis. Subprojects. Consideration of real component geometries (phase 1). Final report; Erhoehung der Komponentensicherheit durch verbesserte Verfahren zur Eigenspannungsanalyse. Teilvorhaben. Beruecksichtigung realer Komponentengeometrien (Phase 1). Abschlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    Nau, Andreas; Scholtes, B.

    2014-07-24

    -axial plane stress states were taken into account in this study. In the case of component's edges minor influences on the calculated stresses could be observed using standard calibration coefficients. Thus, a specific calibration is not considered necessary. The effects on shoulders could be assessed analogously. In the case of the claddings a remarkable influence could only be observed, if their thickness is below 2 mm. Essential benefits were reached through pre-experiments. As a consequence, the experimental execution was improved in terms of the material removal technique. The experimental data preparation was investigated in addition, which lead to the approach not to condition the experimental strains but rather the calculated stresses. This method is important for the experiments of phase 2 within this project. As a consequence of a successful project, the present knowledge base will be considerably improved and will be available for various engineering fields. Especially, the quantitative consideration of real residual stress states for optimized component designs will be feasible and finally the consequences of residual stresses an the component's safety, which are used in nuclear facilities, can be evaluated. The findings of the first numerical and theoretical research period (phase 1) at Kassel University are documented in this report.

  1. Percutaneous Penetration - Methodological Considerations

    DEFF Research Database (Denmark)

    Holmgaard, Rikke; Benfeldt, Eva; Nielsen, Jesper B

    2014-01-01

    developed to replace methods involving experimental animals. The results obtained from these methods are decided not only by the chemical or product tested, but to a significant degree also by the experimental set-up and decisions made by the investigator during the planning phase. The present Mini...

  2. Cobalamin Concentrations in Fetal Liver Show Gender Differences: A Result from Using a High-Pressure Liquid Chromatography-Inductively Coupled Plasma Mass Spectrometry as an Ultratrace Cobalt Speciation Method.

    Science.gov (United States)

    Bosle, Janine; Goetz, Sven; Raab, Andrea; Krupp, Eva M; Scheckel, Kirk G; Lombi, Enzo; Meharg, Andrew A; Fowler, Paul A; Feldmann, Jörg

    2016-12-20

    Maternal diet and lifestyle choices may affect placental transfer of cobalamin (Cbl) to the fetus. Fetal liver concentration of Cbl reflects nutritional status with regards to vitamin B12, but at these low concentration current Cbl measurement methods lack robustness. An analytical method based on enzymatic extraction with subsequent reversed-phase-high-pressure liquid chromatography (RP-HPLC) separation and parallel ICPMS and electrospray ionization (ESI)-Orbitrap-MS to determine specifically Cbl species in liver samples of only 10-50 mg was developed using 14 pig livers. Subsequently 55 human fetal livers were analyzed. HPLC-ICPMS analysis for cobalt (Co) and Cbl gave detection limits of 0.18 ng/g and 0.88 ng/g d.m. in liver samples, respectively, with a recovery of >95%. Total Co (Co t ) concentration did not reflect the amount of Cbl or vitamin B12 in the liver. Cbl bound Co contributes only 45 ± 15% to Co t . XRF mapping and μXANES analysis confirmed the occurrence of non-Cbl cobalt in pig liver hot spots indicating particular Co. No correlations of total cobalt nor Cbl with fetal weight or weeks of gestation were found for the human fetal livers. Although no gender difference could be identified for total Co concentration, female livers were significantly higher in Cbl concentration (24.1 ± 7.8 ng/g) than those from male fetuses (19.8 ± 7.1 ng/g) (p = 0.04). This HPLC-ICPMS method was able to quantify total Co t and Cbl in fetus liver, and it was sensitive and precise enough to identify this gender difference.

  3. Reality show: um paradoxo nietzschiano

    Directory of Open Access Journals (Sweden)

    Ilana Feldman

    2011-01-01

    Full Text Available

    O fenômeno dos reality shows - e a subseqüente relação entre imagem e verdade - assenta-se sobre uma série de paradoxos. Tais paradoxos podem ser compreendidos à luz do pensamento do filósofo alemão Friedrich Nietzsche, que, através dos usos de formulações paradoxais, concebia a realidade como um mundo de pura aparência e a verdade como um acréscimo ficcional, como um efeito. A ficção é então tomada, na filosofia de Nietzsche, não em seu aspecto falsificante e desrealizador - como sempre pleiteou nossa tradição metafísica -, mas como condição necessária para que certa espécie de invenção possa operar como verdade. Sendo assim, a própria expressão reality show, através de sua formulação paradoxal, engendra explicitamente um mundo de pura aparência, em que a verdade, a parte reality da proposição, é da ordem do suplemento, daquilo que se acrescenta ficcionalmente - como um adjetivo - a show. O ornamento, nesse caso, passa a ocupar o lugar central, apontando para o efeito produzido: o efeito-de-verdade. Seguindo, então, o pensamento nietzschiano e sua atualização na contemporaneidade, investigaremos de que forma os televisivos “shows de realidade” operam paradoxalmente, em consonância com nossas paradoxais práticas culturais.

  4. Some considerations on the Tlatelolco Treaty

    International Nuclear Information System (INIS)

    Faria, N.M. de; Goes Fischer, M.D. de

    1981-01-01

    Some considerations related to the Tlatelolco Treaty are focused and so are the role and the position of Brazil in view of the Treaty. Short historical remarks are presented in order to show the commitments of Brazil with the Treaty. Finally, considerations concerned with the validity of the Treaty as the legal instrument to contribute to the security and peace in the World. (Author) [pt

  5. Epigenetic considerations in aquaculture

    Directory of Open Access Journals (Sweden)

    Mackenzie R. Gavery

    2017-12-01

    Full Text Available Epigenetics has attracted considerable attention with respect to its potential value in many areas of agricultural production, particularly under conditions where the environment can be manipulated or natural variation exists. Here we introduce key concepts and definitions of epigenetic mechanisms, including DNA methylation, histone modifications and non-coding RNA, review the current understanding of epigenetics in both fish and shellfish, and propose key areas of aquaculture where epigenetics could be applied. The first key area is environmental manipulation, where the intention is to induce an ‘epigenetic memory’ either within or between generations to produce a desired phenotype. The second key area is epigenetic selection, which, alone or combined with genetic selection, may increase the reliability of producing animals with desired phenotypes. Based on aspects of life history and husbandry practices in aquaculture species, the application of epigenetic knowledge could significantly affect the productivity and sustainability of aquaculture practices. Conversely, clarifying the role of epigenetic mechanisms in aquaculture species may upend traditional assumptions about selection practices. Ultimately, there are still many unanswered questions regarding how epigenetic mechanisms might be leveraged in aquaculture.

  6. Design considerations for energy efficient, resilient, multi-layer networks

    DEFF Research Database (Denmark)

    Fagertun, Anna Manolova; Hansen, Line Pyndt; Ruepp, Sarah Renée

    2016-01-01

    measures. In this complex problem, considerations such as client traffic granularity, applied grooming policies and multi-layer resiliency add even more complexity. A commercially available network planning tool is used to investigate the interplay between different methods for resilient capacity planning......This work investigates different network design considerations with respect to energy-efficiency, under green-field resilient multi-layer network deployment. The problem of energy efficient, reliable multi-layer network design is known to result in different trade-offs between key performance....... Switching off low-utilized transport links has been investigated via a pro-active re-routing applied during the network planning. Our analysis shows that design factors such as the applied survivability strategy and the applied planning method have higher impact on the key performance indicators compared...

  7. Educational Neuroscience: Neuroethical Considerations

    Science.gov (United States)

    Lalancette, Helene; Campbell, Stephen R.

    2012-01-01

    Research design and methods in educational neuroscience involve using neuroscientific tools such as brain image technologies to investigate cognitive functions and inform educational practices. The ethical challenges raised by research in social neuroscience have become the focus of neuroethics, a sub-discipline of bioethics. More specifically…

  8. Practical considerations on frenectomy

    Science.gov (United States)

    Moldoveanu, Lucia; Badea, Florin Ciprian; Odor, Alin A.

    2014-01-01

    Besides surgically classical frenectomy, modern dentistry currently allows its approach by dental laser. Materials and Method: We proposed clinical observation of the results obtained by frenectomy with/without frenoplasty made by laser Er,Cr:YSGG 2780 nm. Results: The patients reported no pain, bleeding, swelling or major discomfort during the postoperative control of the following day. In terms of psycho-emotional reactions, both patients well behave well, the calm being given by no pain, bleeding, suture or edema. Discussions: The accuracy of this method, as well as the use of additional means of healing, allow satisfactory results both for patient and physician. Working parameters depend on the type of laser that is used, in our case Biolase Waterlase MD Turbo, regularly used in Toldimed Clinic in Constanta. Conclusions: Our study reveals that the possibilities regarding the surgical modeling of the lower lip frenulum are higher due to laser than the classical surgical approach. Moreover, a major role in the prevention of relapse by inappropriate healing is represented by the approach of frenectomy accompanied by frenuloplasty.

  9. Ethical considerations in sexual health research: A narrative review

    Directory of Open Access Journals (Sweden)

    Maryam Shirmohammadi

    2018-01-01

    Full Text Available Background: There is an assumption that sexual health research has great influence on the quality of human life through elevating sexual health standards, and their results will eliminate the burden of sexual health challenges on family relationships. The aim of this study was to review ethical considerations in sexual health research. Materials and Methods: This narrative review was conducted between January 1990 and December 2017 based on the five-step approach of York University. The keywords used to search for the studies included ethical issues, research, sexual health, reproductive health, and sensitive topics. The language of the literatures was English and the search process was performed on PubMed, Elsevier, Ovid, Springer, Google Scholar, ResearchGate, SAGE Publishing, ProQuest, WHO website, Kinsey Confidential, and Worldsexology. Results: After assessing the quality and eligibility of 94 articles, 13 were selected. The results of the present study showed that the most important ethical considerations were protecting the confidentiality and privacy of participants, obtaining informed consent, and paying attention to vulnerable people. Conclusions: The review of literature exhibited several considerations that sexual health researchers are faced with. In order to manage these considerations, the researcher should have sufficient understanding of them. The important matter is that strategies to manage these challenges should be completely rational and practical according to each context. These strategies can also be applied in other societies with great similarities in their context.

  10. Collaborative assessment and management of suicidality method shows effect

    DEFF Research Database (Denmark)

    Nielsen, Ann Colleen; Alberdi Olano, Francisco Javier Lorenzo; Rosenbaum, Bent

    2011-01-01

    Previous studies confirm the effect of collaborative assessment and management of suicidality (CAMS) in an experimental setup, but there is a need to test CAMS with regard to its effectiveness and feasibility in a real-life clinical context. The purpose of this study was to investigate CAMS in a ...

  11. Environmental considerations and regulations

    International Nuclear Information System (INIS)

    Blanco, R.E.

    1976-01-01

    Methods used to control the radiological impact of the nuclear fuel cycle are described. This control is exercised through the application of a series of federal laws and regulations that are used as the basis for licensing nuclear facilities. The control is exercised more directly by the use of radwaste treatment equipment at the nuclear facilities to limit the release of radioactive materials. Federal laws and regulations are summarized and their applications in licensing actions are discussed. Radiological doses from materials released from licensed facilities are compared with doses from natural background. A series of cost/benefit engineering surveys are being made to determine the cost and effectiveness of radwaste systems for decreasing the release of radioactive materials from model fuel cycle facilities and to determine the benefits in terms of reduction in dose commitment to individuals and populations in surrounding areas

  12. Cosmetic surgery: medicolegal considerations

    Directory of Open Access Journals (Sweden)

    Piras Mauro

    2016-01-01

    Full Text Available Cosmetic surgery is one of the two branches of plastic surgery. The characteristic of non-necessity of this surgical speciality implies an increased severity in the evaluation of the risk-benefit balance. Therefore, great care must be taken in providing all the information necessary in order to obtain valid consent to the intervention. We analyzed judgments concerning cosmetic surgery found in national legal databases. A document of National Bioethics Committee (CNB was also analyzed. Conclusion: The receipt of valid, informed consent is of absolute importance not only to legitimise the medical-surgical act, but it also represents the key element in the question concerning the existence of an obligation to achieve certain results/use of certain methods in the cosmetic surgery.

  13. This research is to study the factors which influence the business success of small business ‘processed rotan’. The data employed in the study are primary data within the period of July to August 2013, 30 research observations through census method. Method of analysis used in the study is multiple linear regressions. The results of analysis showed that the factors of labor, innovation and promotion have positive and significant influence on the business success of small business ‘processed rotan’ simultaneously. The analysis also showed that partially labor has positive and significant influence on the business success, yet innovation and promotion have insignificant and positive influence on the business success.

    OpenAIRE

    Nasution, Inggrita Gusti Sari; Muchtar, Yasmin Chairunnisa

    2013-01-01

    This research is to study the factors which influence the business success of small business ‘processed rotan’. The data employed in the study are primary data within the period of July to August 2013, 30 research observations through census method. Method of analysis used in the study is multiple linear regressions. The results of analysis showed that the factors of labor, innovation and promotion have positive and significant influence on the business success of small busine...

  14. Myopes show increased susceptibility to nearwork aftereffects.

    Science.gov (United States)

    Ciuffreda, K J; Wallis, D M

    1998-09-01

    Some aspects of accommodation may be slightly abnormal (or different) in myopes, compared with accommodation in emmetropes and hyperopes. For example, the initial magnitude of accommodative adaptation in the dark after nearwork is greatest in myopes. However, the critical test is to assess this initial accommodative aftereffect and its subsequent decay in the light under more natural viewing conditions with blur-related visual feedback present, if a possible link between this phenomenon and clinical myopia is to be considered. Subjects consisted of adult late- (n = 11) and early-onset (n = 13) myopes, emmetropes (n = 11), and hyperopes (n = 9). The distance-refractive state was assessed objectively using an autorefractor immediately before and after a 10-minute binocular near task at 20 cm (5 diopters [D]). Group results showed that myopes were most susceptible to the nearwork aftereffect. It averaged 0.35 D in initial magnitude, with considerably faster posttask decay to baseline in the early-onset (35 seconds) versus late-onset (63 seconds) myopes. There was no myopic aftereffect in the remaining two refractive groups. The myopes showed particularly striking accommodatively related nearwork aftereffect susceptibility. As has been speculated and found by many others, transient pseudomyopia may cause or be a precursor to permanent myopia or myopic progression. Time-integrated increased retinal defocus causing axial elongation is proposed as a possible mechanism.

  15. Waste management considerations in HTGR recycle operations

    International Nuclear Information System (INIS)

    Pence, D.T.; Shefcik, J.J.; Heath, C.A.

    1975-01-01

    Waste management considerations in the recycle of HTGR fuel are different from those encountered in the recycle of LWR fuel. The types of waste associated with HTGR recycle operations are discussed, and treatment methods for some of the wastes are described

  16. Photovoltaics: systems considerations

    Energy Technology Data Exchange (ETDEWEB)

    Haq, A M

    1982-08-01

    Photovoltaics applications to date and the potential uses and growth of this alternative energy source for the future are examined in the light of present world economic conditions. In addition, a more detailed description is given, illustrating the method by which system sizing and design are calculated and mentioning such factors as local solar radiation and insolation levels, humidity, wind loading and altitude, all of which affect the optimal system size. The role of computer programming in these calculations is also outlined, illustrating the way in which deterioration, battery losses, poor weather etc. can be accounted and compensated for in the systems design process. The elements of the actual systems are also described, including details of the solar cells and arrays, the electronic controls incorporated in the systems and the characteristics of the batteries used. A resume of projected costs and current technological advances in silicon processing techniques is given together with an analysis of present and future growth trends in the photovoltaics industry.

  17. Safety considerations of PWR's

    International Nuclear Information System (INIS)

    Arnold, W.H. Jr.

    1977-01-01

    as ECCS, as previously noted, ATWS, fire protection, turbine missile and others. Resolution of these issues has emphasized the need for utilizing probability-reliability concepts. Quantitative risk assessment is beginning to play an important role, and its importance is expected to increase, in the industry decision making process as well as the regulatory process. These tools provide a method for further quantifying the safety margins that exist in the present designs, the basis for rational decisions relative to any proposed changes in these designs as well as for any new designs aimed at improving plant safety and availability

  18. Survey on current status of laboratory test method and experimental consideration for establishing standardized procedure of material containing bentonite. Report of collaboration research between JAEA and CRIEPI (Joint research)

    International Nuclear Information System (INIS)

    Tanai, Kenji; Kikuchi, Hirohito; Nakamura, Kunihiko; Tanaka, Yukihisa; Hironaga, Michihiko

    2010-08-01

    In the current concept of repository for radioactive waste disposal, compacted bentonite as well as bentonite based material will be used as an engineered barrier mainly for inhibiting migration of radioactive nuclides. In most cases, properties of bentonite, such as low permeability etc., are obtained by laboratory tests. However, results of laboratory tests of bentonite often vary considerably even if index parameter, such as effective clay density, is constant. One of the causes of the variability is considered to be lack of standardized method of laboratory test for bentonite. Thus standardization of laboratory test methods for bentonite is needed. So, investigation for establishing standardized laboratory test method of bentonite is conducted based on the results of survey on current status of laboratory test method for bentonite. In particular, the literature survey as well as laboratory tests were conducted to find factors affecting the results of laboratory tests for bentonite and to estimate their degree of influence. The following conclusions are obtained through this study. (1) Hydraulic conductivity test. According to the results of literature survey, it is revealed that constant pressure permeability test and consolidation test are currently used for measuring hydraulic conductivity of bentonite and that (a) hydraulic gradient, (b) local seepage flow between lateral surface of the specimen and lateral wall of the container, (c) water pressure which is applied to the specimen, (d) degree of saturation and (e) size of the specimen possibly affect the results of the constant pressure permeability test, while (f) friction between lateral surface of the specimen and lateral wall of the container accompanied by deformation of the specimen, (g) consolidation pressure together with factors (d), (e) affect the results of the consolidation test. Literature which describes that factors (a), (b) and (e) affect the results of the constant pressure permeability test

  19. Advanced LBB methodology and considerations

    International Nuclear Information System (INIS)

    Olson, R.; Rahman, S.; Scott, P.

    1997-01-01

    LBB applications have existed in many industries and more recently have been applied in the nuclear industry under limited circumstances. Research over the past 10 years has evolved the technology so that more advanced consideration of LBB can now be given. Some of the advanced considerations for nuclear plants subjected to seismic loading evaluations are summarized in this paper

  20. Revealed preference with limited consideration

    NARCIS (Netherlands)

    Demuynck, T.; Seel, C.

    2014-01-01

    We derive revealed preference tests for models where individuals use consideration sets to simplify their consumption problem. Our basic test provides necessary and sufficient conditions for consistency of observed choices with the existence of consideration set restrictions. The same conditions can

  1. Ethical Considerations in Technology Transfer.

    Science.gov (United States)

    Froehlich, Thomas J.

    1991-01-01

    Examines ethical considerations involved in the transfer of appropriate information technology to less developed countries. Approaches to technology are considered; two philosophical frameworks for studying ethical considerations are discussed, i.e., the Kantian approach and the utilitarian perspective by John Stuart Mill; and integration of the…

  2. Advanced LBB methodology and considerations

    Energy Technology Data Exchange (ETDEWEB)

    Olson, R.; Rahman, S.; Scott, P. [Battelle, Columbus, OH (United States)] [and others

    1997-04-01

    LBB applications have existed in many industries and more recently have been applied in the nuclear industry under limited circumstances. Research over the past 10 years has evolved the technology so that more advanced consideration of LBB can now be given. Some of the advanced considerations for nuclear plants subjected to seismic loading evaluations are summarized in this paper.

  3. Design Considerations | Efficient Windows Collaborative

    Science.gov (United States)

    Foundry Foundry New Construction Windows Window Selection Tool Selection Process Design Guidance Installation Replacement Windows Window Selection Tool Assessing Options Selection Process Design Guidance Installation Understanding Windows Benefits Design Considerations Measuring Performance Performance Standards

  4. State/Federal Regulatory Considerations

    Science.gov (United States)

    This page contains presentations from the Brown to Green: Make the Connection to Renewable Energy workshop held in Santa Fe, New Mexico, during December 10-11, 2008, regarding State/Federal Regulatory Considerations.

  5. Materials considerations in accelerator targets

    International Nuclear Information System (INIS)

    Peacock, H. B. Jr.; Iyer, N. C.; Louthan, M. R. Jr.

    1995-01-01

    Future nuclear materials production and/or the burn-up of long lived radioisotopes may be accomplished through the capture of spallation produced neutrons in accelerators. Aluminum clad-lead and/or lead alloys has been proposed as a spallation target. Aluminum was the cladding choice because of the low neutron absorption cross section, fast radioactivity decay, high thermal conductivity, and excellent fabricability. Metallic lead and lead oxide powders were considered for the target core with the fabrication options being casting or powder metallurgy (PM). Scoping tests to evaluate gravity casting, squeeze casting, and casting and swaging processes showed that, based on fabricability and heat transfer considerations, squeeze casting was the preferred option for manufacture of targets with initial core cladding contact. Thousands of aluminum clad aluminum-lithium alloy core targets and control rods for tritium production have been fabricated by coextrusion processes and successfully irradiated in the SRS reactors. Tritium retention in, and release from, the coextruded product was modeled from experimental and operational data. The model assumed that tritium atoms, formed by the 6Li(n,a)3He reaction, were produced in solid solution in the Al-Li alloy. Because of the low solubility of hydrogen isotopes in aluminum alloys, the irradiated Al-Li rapidly became supersaturated in tritium. Newly produced tritium atoms were trapped by lithium atoms to form a lithium tritide. The effective tritium pressure required for trap or tritide stability was the equilibrium decomposition pressure of tritium over a lithium tritide-aluminum mixture. The temperature dependence of tritium release was determined by the permeability of the cladding to tritium and the local equilibrium at the trap sites. The model can be used to calculate tritium release from aluminum clad, aluminum-lithium alloy targets during postulated accelerator operational and accident conditions. This paper describes

  6. Materials considerations in accelerator targets

    International Nuclear Information System (INIS)

    Peacock, H.B. Jr.; Iyer, N.C.; Louthan, M.R. Jr.

    1994-01-01

    Future nuclear materials production and/or the burn-up of long lived radioisotopes may be accomplished through the capture of spallation produced neutrons in accelerators. Aluminum clad-lead and/or lead alloys has been proposed as a spallation target. Aluminum was the cladding choice because of the low neutron absorption cross section, fast radioactivity decay, high thermal conductivity, and excellent fabricability. Metallic lead and lead oxide powders were considered for the target core with the fabrication options being casting or powder metallurgy (PM). Scoping tests to evaluate gravity casting, squeeze casting, and casting and swaging processes showed that, based on fabricability and heat transfer considerations, squeeze casting was the preferred option for manufacture of targets with initial core cladding contact. Thousands of aluminum clad aluminum-lithium alloy core targets and control rods for tritium production have been fabricated by coextrusion processes and successfully irradiated in the SRS reactors. Tritium retention in, and release from the coextruded product was modeled from experimental and operational data. Newly produced tritium atoms were trapped by lithium atoms to form a lithium tritide. The effective tritium pressure required for trap or tritide stability was the equilibrium decomposition pressure of tritium over a lithium tritide-aluminum mixture. The temperature dependence of tritium release was determined by the permeability of the cladding to tritium and the local equilibrium at the trap sites. The model can be used to calculate tritium release from aluminum clad, aluminum-lithium alloy targets during postulated accelerator operational and accident conditions. This paper describes the manufacturing technologies evaluated and presents the model for tritium retention in aluminum clad, aluminum-lithium alloy tritium production targets

  7. Magna-field irradiation: physical considerations

    Energy Technology Data Exchange (ETDEWEB)

    Van Dyk, J.

    1983-12-01

    Magna-field radiotherapy in the form of total body, half body and total nodal irradiation is becoming increasingly prominent and involves dosimetric problems that are much more pronounced than they are for conventional field sizes. In this review of the physical considerations of magna-field irradiation, a number of possible alternate methods of producing large radiation fields are outlined, the basic beam dosimetry is reviewed and the factors producing dose variation in the patient are considered. Since the lung contains large regions of low density tissues and has a lower tolerance to radiaiton than most other tissues, special consideration is given to methods of dose determination and dose reduction to this organ. The question of accuracy in dose delivery is briefly discussed and the concept of delivering a radiation dose 'as precisely as readily achievable (APARA), technological and biological factors being taken into account' is introduced.

  8. Method

    Directory of Open Access Journals (Sweden)

    Ling Fiona W.M.

    2017-01-01

    Full Text Available Rapid prototyping of microchannel gain lots of attention from researchers along with the rapid development of microfluidic technology. The conventional methods carried few disadvantages such as high cost, time consuming, required high operating pressure and temperature and involve expertise in operating the equipment. In this work, new method adapting xurography method is introduced to replace the conventional method of fabrication of microchannels. The novelty in this study is replacing the adhesion film with clear plastic film which was used to cut the design of the microchannel as the material is more suitable for fabricating more complex microchannel design. The microchannel was then mold using polymethyldisiloxane (PDMS and bonded with a clean glass to produce a close microchannel. The microchannel produced had a clean edge indicating good master mold was produced using the cutting plotter and the bonding between the PDMS and glass was good where no leakage was observed. The materials used in this method is cheap and the total time consumed is less than 5 hours where this method is suitable for rapid prototyping of microchannel.

  9. Statistical considerations on safety analysis

    International Nuclear Information System (INIS)

    Pal, L.; Makai, M.

    2004-01-01

    The authors have investigated the statistical methods applied to safety analysis of nuclear reactors and arrived at alarming conclusions: a series of calculations with the generally appreciated safety code ATHLET were carried out to ascertain the stability of the results against input uncertainties in a simple experimental situation. Scrutinizing those calculations, we came to the conclusion that the ATHLET results may exhibit chaotic behavior. A further conclusion is that the technological limits are incorrectly set when the output variables are correlated. Another formerly unnoticed conclusion of the previous ATHLET calculations that certain innocent looking parameters (like wall roughness factor, the number of bubbles per unit volume, the number of droplets per unit volume) can influence considerably such output parameters as water levels. The authors are concerned with the statistical foundation of present day safety analysis practices and can only hope that their own misjudgment will be dispelled. Until then, the authors suggest applying correct statistical methods in safety analysis even if it makes the analysis more expensive. It would be desirable to continue exploring the role of internal parameters (wall roughness factor, steam-water surface in thermal hydraulics codes, homogenization methods in neutronics codes) in system safety codes and to study their effects on the analysis. In the validation and verification process of a code one carries out a series of computations. The input data are not precisely determined because measured data have an error, calculated data are often obtained from a more or less accurate model. Some users of large codes are content with comparing the nominal output obtained from the nominal input, whereas all the possible inputs should be taken into account when judging safety. At the same time, any statement concerning safety must be aleatory, and its merit can be judged only when the probability is known with which the

  10. method

    Directory of Open Access Journals (Sweden)

    L. M. Kimball

    2002-01-01

    Full Text Available This paper presents an interior point algorithm to solve the multiperiod hydrothermal economic dispatch (HTED. The multiperiod HTED is a large scale nonlinear programming problem. Various optimization methods have been applied to the multiperiod HTED, but most neglect important network characteristics or require decomposition into thermal and hydro subproblems. The algorithm described here exploits the special bordered block diagonal structure and sparsity of the Newton system for the first order necessary conditions to result in a fast efficient algorithm that can account for all network aspects. Applying this new algorithm challenges a conventional method for the use of available hydro resources known as the peak shaving heuristic.

  11. Design considerations for mechanical snubbers

    International Nuclear Information System (INIS)

    Severud, L.K.; Summers, G.D.

    1980-03-01

    The use of mechanical snubbers to restrain piping during an earthquake event is becoming more common in design of nuclear power plants. The design considerations and qualification procedures for mechanical snubbers used on the Fast Flux Test Facility will be presented. Design precautions and requirements for both normal operation and seismic operation are necessary. Effects of environmental vibration (nonseismic) induced through the piping by pump shaft imbalance and fluid flow oscillations will be addressed. Also, the snubber dynamic characteristics of interest to design and snubber design application considerations will be discussed

  12. LABORATORY DESIGN CONSIDERATIONS FOR SAFETY.

    Science.gov (United States)

    National Safety Council, Chicago, IL. Campus Safety Association.

    THIS SET OF CONSIDERATIONS HAS BEEN PREPARED TO PROVIDE PERSONS WORKING ON THE DESIGN OF NEW OR REMODELED LABORATORY FACILITIES WITH A SUITABLE REFERENCE GUIDE TO DESIGN SAFETY. THERE IS NO DISTINCTION BETWEEN TYPES OF LABORATORY AND THE EMPHASIS IS ON GIVING GUIDES AND ALTERNATIVES RATHER THAN DETAILED SPECIFICATIONS. AREAS COVERED INCLUDE--(1)…

  13. General B factory design considerations

    International Nuclear Information System (INIS)

    Zisman, M.S.

    1992-12-01

    We describe the general considerations that go into the design of an asymmetric B factory collider. Justification is given for the typical parameters of such a facility, and the physics and technology challenges that arise from these parameter choices are discussed. Cost and schedule issues for a B factory are discussed briefly. A summary of existing proposals is presented, noting their similarities and differences

  14. Practical considerations for effective microendoscopy

    Science.gov (United States)

    Papaioannou, Thanassis; Papazoglou, Theodore G.; Daykhovsky, Leon; Gershman, Alex; Segalowitz, Jacob; Reznik, G.; Beeder, Clain; Chandra, Mudjianto; Grundfest, Warren S.

    1991-07-01

    This paper reports on the application of angioscopic technology to the endoscopy of previously inaccessible body cavities. Necessary instruments including endoscopes, light sources, cameras, video recorders, monitors, and other accessories are described. Practical considerations for effective instrumentation are discussed. An overview of our clinical microendoscopic applications in more than 630 patients is presented.

  15. Ethical Considerations in Research Participation Virality.

    Science.gov (United States)

    Ellis-Barton, Carol

    2016-07-01

    This article seeks to commence and encourage discussion around the upcoming ethical challenges of virality in network structures. When the call for participation in a research project on lupus in Ireland went from an advertisement in a newsletter to a meme (unit of transmissible information) on a closed Facebook page, the ethical considerations of virality were raised. The article analyzes the Association of Internet Researchers guidelines, Facebook policies, and the context of privacy in relation to virality. Virality creates the leverage for methodological pluralism. The nature of the inquiry can determine the method rather than the other way around. Viral ethical considerations are evolving due to the cyber world becoming the primary meme of communication, with flexibility in the researcher's protocol providing opportunities for efficient, cost-effective, and diverse recruitment. © The Author(s) 2016.

  16. Noise Considerations for V/STOL Transports

    Science.gov (United States)

    Kenyon, George C.

    1968-01-01

    Noise consideration may well be as important a factor in future aircraft concept selection as such economic factors as operating cost and profitability. The impact of noise on some of the design and operational aspects of future V/STOL transports is examined in detail, including consideration of configuration, attitude-control system, lift system, and terminal flight pattern. Extended vertical rise of VTOL aircraft as a method of limiting the intense noise exposure to the terminal area is shown to be only partially effective as well as costly. Comparisons are made of noise contours for conceptual V/STOL transports for several PNdB criteria. The variation in extent of affected area with configuration and criterion emphasizes the importance of establishing an "acceptable" noise level for "city-center" operation.

  17. Methods for constructing time synchronous networks. Part 1. Consideration and experiment of time synchronizing functions and devices; Zenkei jikoku dokimo no kosei shuho. 1. Jikoku doki hoshiki no kino kento to jikkenteki kensho

    Energy Technology Data Exchange (ETDEWEB)

    Serizawa, Y.; Kitamura, K.; Myojin, M.; Shimizu, K. [Central Research Institute of Electric Power Industry, Tokyo (Japan); Nenohi, H.; Morimitsu, M.; Masui, O.; Matsushima, T. [NEC Corp., Tokyo (Japan)

    1996-03-01

    For the purpose of the back-up protection of regional power line system and the protection and control of accident influence, construction methods of time synchronizing network have been investigated. This paper proposes a method suitable for business power communication. For the synchronization between stations, transmission delay and its fluctuation have to be measured accurately by transmitting time signals between stations. Based on the observed delay values, the function of time correction (phase synchronizing control) of synchronized station is required. A mutual type synchronizing method was proposed, to which a sampling synchronization method of carrier relay system for transmission line protection was applied. In this method, transmission of time signals and measurement of delays are mutually conducted between stations, and phases of independent transmitters of the both stations are controlled so as to be equivalent. This method is characterized by the suppression of delays with fluctuation in the same direction of two-way transmission. For the transmission of time signals, two types of synchronizing devices were employed, i.e., synchronous and asynchronous manners. In the former, frequency synchronous network of SDH (synchronous digital hierarchy) was synchronized. In the latter, a carrier relay device was utilized independent of frequency synchronous network. It was expected that a synchronous network with an order of {mu}s can be constructed. 11 refs., 21 figs., 3 tabs.

  18. Team building: conceptual, methodological, and applied considerations.

    Science.gov (United States)

    Beauchamp, Mark R; McEwan, Desmond; Waldhauser, Katrina J

    2017-08-01

    Team building has been identified as an important method of improving the psychological climate in which teams operate, as well as overall team functioning. Within the context of sports, team building interventions have consistently been found to result in improvements in team effectiveness. In this paper we review the extant literature on team building in sport, and address a range of conceptual, methodological, and applied considerations that have the potential to advance theory, research, and applied intervention initiatives within the field. This involves expanding the scope of team building strategies that have, to date, primarily focused on developing group cohesion. Copyright © 2017 Elsevier Ltd. All rights reserved.

  19. Review of specific radiological accident considerations

    International Nuclear Information System (INIS)

    Elder, J.

    1984-01-01

    Specific points of guidance provided in the forthcoming document A Guide to Radiological Accident Considerations for Siting and Design of Nonreactor Nuclear Facilities are discussed. Of these, the following are considered of particular interest to analysts of hypothetical accidents: onsite dose limits; population dose, public health effects, and environmental contamination as accident consequences which should be addressed; risk analysis; natural phenomena as accident initiators; recommended dose models; multiple organ equivalent dose; and recommended methods and parameters for source terms and release amount calculations. Comments are being invited on this document, which is undergoing rewrite after the first stage of peer review

  20. Blood donor show behaviour after an invitation to donate : The influence of collection site factors

    NARCIS (Netherlands)

    Merz, E.-M.; Zijlstra, B.J.H.; de Kort, W.L.A.M.

    2017-01-01

    Background and Objectives Show behaviour after invitation to donate varies considerably across donors. More insight into this variation is important for blood banks in achieving stable stocks. This study examined individual factors determining intended show behaviour. Most importantly, however, this

  1. Blood donor show behavior after an invitation to donate: The influence of collection site factors

    NARCIS (Netherlands)

    Merz, E.M.; Zijlstra, Bonne; De Kort, Wim L.A.M.

    2017-01-01

    Background and Objectives Show behaviour after invitation to donate varies considerably across donors. More insight into this variation is important for blood banks in achieving stable stocks. This study examined individual factors determining intended show behaviour. Most importantly, however, this

  2. IEA Shows Concerns Over China's Oil Stockpiling

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    @@ Reportedly, China's oil imports accounted for nearly one third of the world's total oil supply in 2003. The country's oil imports are estimated at 110~120 million tons in 2004,equal to 2.2~2.4 million barrels per day, much higher than 91 million tons in 2003. International Energy Agency has helped the Chinese government with the country's strategic oil stockpiling plan by offering the training. The Paris-based IEA has urged China to take into consideration how to operate and maintain the national strategic oil stockpiling system and clarify the roles of the enterprises and the State in oil stockpiling.

  3. Commercial considerations in tissue engineering.

    Science.gov (United States)

    Mansbridge, Jonathan

    2006-10-01

    Tissue engineering is a field with immense promise. Using the example of an early tissue-engineered skin implant, Dermagraft, factors involved in the successful commercial development of devices of this type are explored. Tissue engineering has to strike a balance between tissue culture, which is a resource-intensive activity, and business considerations that are concerned with minimizing cost and maximizing customer convenience. Bioreactor design takes place in a highly regulated environment, so factors to be incorporated into the concept include not only tissue culture considerations but also matters related to asepsis, scaleup, automation and ease of use by the final customer. Dermagraft is an allogeneic tissue. Stasis preservation, in this case cryopreservation, is essential in allogeneic tissue engineering, allowing sterility testing, inventory control and, in the case of Dermagraft, a cellular stress that may be important for hormesis following implantation. Although the use of allogeneic cells provides advantages in manufacturing under suitable conditions, it raises the spectre of immunological rejection. Such rejection has not been experienced with Dermagraft. Possible reasons for this and the vision of further application of allogeneic tissues are important considerations in future tissue-engineered cellular devices. This review illustrates approaches that indicate some of the criteria that may provide a basis for further developments. Marketing is a further requirement for success, which entails understanding of the mechanism of action of the procedure, and is illustrated for Dermagraft. The success of a tissue-engineered product is dependent on many interacting operations, some discussed here, each of which must be performed simultaneously and well.

  4. Considerations Regarding Students’ Social Protection

    Directory of Open Access Journals (Sweden)

    Iuliana Cenar

    2016-01-01

    Full Text Available The paper entitled “Considerations Regarding Students’ Social Protection” addresses the main forms of support offered to students and their families, divided in relation to the aim pursued, which may be relate to stimulating students’ performance and discipline, material and financial support (social assistance, supplementing family income. For these components there were taken into account: the circumstances in which it acquires to status of beneficiary, evolutionary dimensions in terms of beneficiary numbers, the amounts awarded, the need to ensure the complementarities with the informal side of social protection.

  5. On the relationship of cytoplasmic and nuclear 3H-estradiol bonding in human mammary carcinoma cells with special consideration of the sucrose density centrifugation in comparison to the charcoal method

    International Nuclear Information System (INIS)

    Semm, D.M.

    1982-01-01

    According to a hypothesis from Wittliff an estrogen-positive-receptor tumor would indicate the need for endrocrinological therapy if after sucrose density centrifugation on S-peak of 8-9 is found. In this work this hypothesis is studied, the sucrose density centrifugation is compared to the charcoal method, a normal value range is determined for the sucrose density centrifugation and the amount of cytoplasmic estrogen bonding is correlated with the estrogen chromatin bonding capacity. With malignantly degenerated breast cells the average 3 H-estradiol bonding capacities for the charcoal method were 74.09 fmol/mg protein and respectively 22.9 fmol/mg protein with incubation in 2.5x10 -8 M 3 H-estradiol. For the sucrose density centrifugation 42.81 fmol/mg protein was found as average value in the peak fraction (4-5 S-range). With the use of the charcoal method 78% of the carcinoma were estrogen-receptor positive compared to 57% using the sucrose density centrifugation (n=23). The average nucleus bonding amount in the case of 15 carcinomas which were studied for their estradiol chromatin bonding capacity was 588.1 dpm/1 μg DNA. Together with the estradiol receptor analysis the determination of nucleus bonding capacity appears to be a promising procedure especially for postclimacteric women for reducing the rate of non-responders. Beyond that this receptor combination could offer a contribution to the malignancy grading of nuclear mastopathy results procedure. Wittliff's hypothesis, a tumor is first estrogen sensitive when an 8-9 S-peak is present, could not be confirmed. Neither could the 8-9 S-peaks in the form given by Wittliff be reproduced nor could any positive correlation to cytoplasmic bonding or respectively to 3 H-estradiol chromatin bonding be found. (orig.) [de

  6. Analyzing and Improving the Water-Table Fluctuation Method of Estimating Groundwater Recharge: Field Considerations Patros, T.B. and Parkin, G.W., School of Environmental Sciences, University of Guelph, Guelph, Ontario, Canada

    Science.gov (United States)

    Patros, T.; Parkin, G. W.

    2012-12-01

    The focus of the project is on measuring and quantifying groundwater recharge (GWR) using the water-table fluctuation (WTF) method. This method requires measuring the change in water-table (WT) height (Δh) during recharge (R) events and volumetric soil specific yield water content (θsy), (&/or) perhaps more correctly volumetric soil fillable water content (θf). The rise in WT can also result from other non-precipitation-related WTF causes (e.g., Lisse effect, temperature variations, barometric, lateral flow, Reverse Wieringermeer effect, encapsulated air, pumping), which must be counted for. The measurement of the storativity (S) terms (θsy) and/or θf) is, indeed, not clear-cut and often they are taken as being constant with depth, time, WT movement (Drying-Wetting & Freezing-Thawing) history and heterogeneity. In fact, these two terms (θsy & θf) are controversial in their definition, thus in their use, in the literature and may either overestimate the R, when using θsy, or underestimate it, when using θf. To resolve some of these questions, a novel-automated method is under development, at the University of Guelph's Elora Research Station (ERS) and Arboretum, along with a novel multi-event time series model. The long-term expected outcomes and significance of this study are; 1. Establishing accuracy in defining and evaluating the θsy and θf and using them accordingly in estimating GWR with the WTF method in order to overcome some of the existing substantial gaps in our knowledge of groundwater (GW) storage variation. 2. Obtaining GWR measurements at the local scale on a year-round basis, which are currently scarce or even completely lacking for many regions of Ontario and thus would provide a valuable database for guiding development of any policy requiring GWR. 3. Using this database to calibrate and test estimates of the spatial and temporal variability in regional-scale (watershed scale) GWR from approximate statistical techniques or deterministic

  7. 28 CFR 51.34 - Expedited consideration.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Expedited consideration. 51.34 Section 51... consideration. (a) When a submitting authority is required under State law or local ordinance or otherwise finds... the submission be given expedited consideration. The submission should explain why such consideration...

  8. 46 CFR 114.550 - Special consideration.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Special consideration. 114.550 Section 114.550 Shipping... consideration. In applying the provisions of this subchapter, the OCMI may give special consideration to... vessel operates must approve any special consideration granted to the vessel. ...

  9. Emollient treatment of atopic dermatitis: latest evidence and clinical considerations

    Directory of Open Access Journals (Sweden)

    Kam Lun Hon

    2018-04-01

    Full Text Available Aim: To review current classes of emollients in the market, their clinical efficacy in atopic dermatitis (AD and considerations for choice of an emollient. Methods: PubMed Clinical Queries under Clinical Study Categories (with Category limited to Therapy and Scope limited to Narrow and Systematic Reviews were used as the search engine. Keywords of ‘emollient or moisturizer’ and ‘atopic dermatitis’ were used. Overview of findings: Using the keywords of ‘emollient’ and ‘atopic dermatitis’, there were 105 and 36 hits under Clinical Study Categories (with Category limited to Therapy and Scope limited to Narrow and Systematic Reviews, respectively. Plant-derived products, animal products and special ingredients were discussed. Selected proprietary products were tabulated. Conclusions: A number of proprietary emollients have undergone trials with clinical data available on PubMed-indexed journals. Most moisturizers showed some beneficial effects, but there was generally no evidence that one moisturizer is superior to another. Choosing an appropriate emollient for AD patients would improve acceptability and adherence for emollient treatment. Physician’s recommendation is the primary consideration for patients when selecting a moisturizer/ emollient; therefore, doctors should provide evidence-based information about these emollients.

  10. Technical considerations during disinfection by UV

    International Nuclear Information System (INIS)

    Ekhtiarzadeh, Z.; Sadeghpur, H.

    2002-01-01

    The use of new methods for treatment of water and wastewater in the country is one the rise and therefore the theoretical and practical knowledge of the industry's engineers should increase simultaneously. Ultraviolet is one of the new technologies used both for treatment of water as well as wastewater. The UV disinfection system consists of different components such as the lamp, ballast and the lamp fixtures. Each has a specification, which should be taken into account prior to design, order and purchase. The subject of price is also among the important considerations. The article presents figures cost comparison in various sections. It does not try to either approve or reject other disinfection systems such as chlorination, but the writer believes that any method should find its own practice and conditions of use, and the disinfection system designers should opt for the best system suited to their plans and avoid limiting themselves to a single one

  11. Increased component safety through improved methods for residual stress analysis. Subprojects. Consideration of the elastic-plastic material properties (phase 1). Final report; Erhoehung der Komponentensicherheit durch verbesserte Verfahren zur Eigenspannungsanalyse. Teilvorhaben. Beruecksichtigung der elastisch-plastischen Materialeigenschaften (Phase 1). Abschlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    Mirbach, David von

    2014-07-28

    Residual stresses in mechanical components can result in both detrimental but also beneficial effects on the strength and lifetime of the components. The most detailed knowledge of the residual stress state is of advantage or a pre-requisite for the assessment of the component performance. The mechanical methods for residual stress measurement are divided into the groups of non-destructive and destructive methods. Two commonly used mechanical methods for determination of residual stresses are the hole drilling method and the ring core method which can be regarded as semi-destructive methods. In the context of reactor safety research of the German Federal Ministry of Economic and Technology (BMWi) two fundamental and interacting weak points of the hole drilling method as well as of the ring core method, respectively, in order to determine residual stresses are going to be investigated. As a consequence reliability of the methods will be improved in this joint research project. On the one hand there are effects of geometrical boundary conditions of the components and on the other hand there is the influence of plasticity due to notch effects both affecting the released strain field after removing material and after all the calculated residual stresses. The first issue mentioned above is under the responsibility of the Institute of Materials Engineering (Kassel University) and the last one is investigated by Universitaet of Stuttgart-Otto-Graf-Institut - materials testing institute. As a consequence of a successful project the knowledge base will be considerably improved resulting in benefits for various engineering fields. Especially the quantitative consideration of real residual stress states for optimized component designs will be possible and after all the consequences of residual stresses on safety of components which are used in nuclear facilities can be evaluated. The state of art was reground in the first research chapter and the analysed strain gauges where

  12. Shaft and tunnel sealing considerations

    International Nuclear Information System (INIS)

    Kelsall, P.C.; Shukla, D.K.

    1980-01-01

    Much of the emphasis of previous repository sealing research has been placed on plugging small diameter boreholes. It is increasingly evident that equal emphasis should now be given to shafts and tunnels which constitute more significant pathways between a repository and the biosphere. The paper discusses differences in requirements for sealing shafts and tunnels as compared with boreholes and the implications for seal design. Consideration is given to a design approach for shaft and tunnel seals based on a multiple component design concept, taking into account the requirements for retrievability of the waste. A work plan is developed for the future studies required to advance shaft and tunnel sealing technology to a level comparable with the existing technology for borehole sealing

  13. Sodium concrete reaction - Structural considerations

    International Nuclear Information System (INIS)

    Ferskakis, G.N.

    1984-01-01

    An overview of the sodium concrete reaction phenomenon, with emphasis on structural considerations, is presented. Available test results for limestone, basalt, and magnetite concrete with various test article configurations are reviewed. Generally, tests indicate reaction is self limiting before all sodium is used. Uncertainties, however, concerning the mechanism for penetration of sodium into concrete have resulted in different theories about a reaction model. Structural behavior may be significant in the progression of the reaction due to thermal-structuralchemical interactions involving tensile cracking, compressive crushing, or general deterioration of concrete and the exposure of fresh concrete surfaces to react with sodium. Structural behavior of test articles and potential factors that could enhance the progression of the reaction are discussed

  14. Biosimilars: Considerations for Oncology Nurses
.

    Science.gov (United States)

    Vizgirda, Vida; Jacobs, Ira

    2017-04-01

    Biosimilars are developed to be highly similar to and treat the same conditions as licensed biologics. As they are approved and their use becomes more widespread, oncology nurses should be aware of their development and unique considerations. This article reviews properties of biosimilars; their regulation and approval process; the ways in which their quality, safety, and efficacy are evaluated; their postmarketing safety monitoring; and their significance to oncology nurses and oncology nursing.
. A search of PubMed and regulatory agency websites was conducted for references related to the development and use of biosimilars in oncology. 
. Because biologics are large, structurally complex molecules, biosimilars cannot be considered generic equivalents to licensed biologic products. Consequently, regulatory approval for biosimilars is different from approval for small-molecule generics. Oncology nurses are in a unique position to educate themselves, other clinicians, and patients and their families about biosimilars to ensure accurate understanding, as well as optimal and safe use, of biosimilars.

  15. Lyme Disease: Emergency Department Considerations.

    Science.gov (United States)

    Applegren, Nathan D; Kraus, Chadd K

    2017-06-01

    Lyme disease (LD) is the most common vector-borne illness in North America. Reported cases of LD have increased from approximately 10,000 cases annually in 1991 to >25,000 cases in 2014. Greater recognition, enhanced surveillance, and public education have contributed to the increased prevalence, as have geographic expansion and the number of infected ticks. Cases are reported primarily in the Northeastern United States, Wisconsin, and Minnesota, with children having the highest incidence of LD among all age groups. The increased incidence and prevalence of LD in the United States makes it increasingly more common for patients to present to the emergency department (ED) for tick bites and LD-related chief complaints, such as the characteristic erythema migrans skin manifestation. We sought to review the etiology of LD, describe its clinical presentations and sequela, and provide a practical classification and approach to ED management of patients with LD-related presentations. In this review, ED considerations for LD are presented and clinical presentations and management of the disease at different stages is discussed. Delayed sequelae that have significant morbidity, including Lyme carditis and Lyme neuroborreliosis, are discussed. Diagnostic tests and management are described in detail. The increasing prevalence and growing geographic reach of Lyme disease makes it critically important for emergency physicians to consider the diagnosis in patients presenting with symptoms suggestive of LD and to initiate appropriate treatment to minimize the potential of delayed sequelae. Special consideration should be made for the epidemiology of LD and a high clinical suspicion should be present for patients in endemic areas or with known exposures to ticks. Emergency physicians can play a critical role in the recognition, diagnosis, and treatment of LD. Copyright © 2017 Elsevier Inc. All rights reserved.

  16. Best in show but not best shape: a photographic assessment of show dog body condition.

    Science.gov (United States)

    Such, Z R; German, A J

    2015-08-01

    Previous studies suggest that owners often wrongly perceive overweight dogs to be in normal condition. The body shape of dogs attending shows might influence owners' perceptions, with online images of overweight show winners having a negative effect. This was an observational in silico study of canine body condition. 14 obese-prone breeds and 14 matched non-obese-probe breeds were first selected, and one operator then used an online search engine to identify 40 images, per breed, of dogs that had appeared at a major national UK show (Crufts). After images were anonymised and coded, a second observer subjectively assessed body condition, in a single sitting, using a previously validated method. Of 1120 photographs initially identified, 960 were suitable for assessing body condition, with all unsuitable images being from longhaired breeds. None of the dogs (0 per cent) were underweight, 708 (74 per cent) were in ideal condition and 252 (26 per cent) were overweight. Pugs, basset hounds and Labrador retrievers were most likely to be overweight, while standard poodles, Rhodesian ridgebacks, Hungarian vizslas and Dobermanns were least likely to be overweight. Given the proportion of show dogs from some breeds that are overweight, breed standards should be redefined to be consistent with a dog in optimal body condition. British Veterinary Association.

  17. Reprocessing considerations for a developing country

    International Nuclear Information System (INIS)

    This paper describes some of the alternatives for dealing with spent fuel that face a developing country. It then discusses the considerations that affect decisions on the size and siting of reprocessing plants, and shows how small plants may be suitable in countries without the means to transport spent fuel easily. The paper also outlines the reasons for reprocessing in India, and describes the development of India's reprocessing capability. It shows how the economic conditions in India, such as low skilled labour costs, make reprocessing plants of 100 to 200 tonnes U/yr capacity economic, and includes a table giving technical data on a 100 t U/yr national plant for inclusion in the reference cases used by INFCE Working Group 4

  18. Considerations for emotion-aware consumer products.

    Science.gov (United States)

    van den Broek, Egon L; Westerink, Joyce H D M

    2009-11-01

    Emotion-aware consumer products require reliable, short-term emotion assessment (i.e., unobtrusive, robust, and lacking calibration). To explore the feasibility of this, an experiment was conducted where the galvanic skin response (GSR) and three electromyography (EMG) signals (frontalis, corrugator supercilii, and zygomaticus major) were recorded on 24 participants who watched eight 2-min emotion inducing film fragments. The unfiltered psychophysiological signals were processed and six statistical parameters (i.e., mean, absolute deviation, standard deviation, variance, skewness, and kurtosis) were derived for each 10-s interval of the film fragment. For each physiological signal, skewness and kurtosis discriminated among affective states, accompanied by other parameters, depending on the signal. The skewness parameter also showed to indicate mixed emotions. Moreover, a mapping of events in the fragments on the signals showed the importance of short-term emotion assessment. Hence, this research identified generic features, denoted important considerations, and illustrated the feasibility of emotion-aware consumer products.

  19. Considerations on field problem structure

    International Nuclear Information System (INIS)

    Pavelescu, M.

    1977-01-01

    A survey of the three field problem types known today: equilibrium, eigen value and propagation problems is presented. The place occupied by neutron field in the nuclear reactor systems both statics and dynamics is shown. The special class of approximate solution method concerning the solving of field and boundary equations is analysed. The residual and variational method and the finite element method which presents a special interest are examined as well. (author)

  20. Increased component safety through improved methods for residual stress analysis. Subprojects. Consideration of the elastic-plastic material properties (Phase 2). Final report; Erhoehung der Komponentensicherheit durch verbesserte Verfahren zur Eigenspannungsanalyse. Teilvorhaben. Beruecksichtigung der elastisch-plastischen Materialeigenschaften (Phase 2). Abschlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    Mirbach, David von

    2015-12-16

    Residual stresses in mechanical components can result in both detrimental but also beneficial effects on the strength and lifetime of the components. The most detailed knowledge of the residual stress state is of advantage or a pre-requisite for the assessment of the component performance. Two commonly used methods for determination of residual stresses are the hole drilling method and the ring core method which can be regarded to the mechanical methods. In the context of reactor safety research of the German Federal Ministry of Economic and Energy (BMWi) two fundamental and interacting weak points of the hole drilling method as well as of the ring core method, respectively, in order to determine residual stresses are going to be investigated. As a consequence reliability of the methods will be improved in this joint research project. On the one hand there are effects of geometrical boundary conditions of the components and on the other hand there is the influence of plasticity due to notch effects both affecting the released strain field after removing material and after all the calculated residual stresses. The first issue mentioned above is under the responsibility of the Institute of Materials Engineering (Kassel University) and the last one is investigated by materials testing institute university Stuttgart. As a consequence of a successful project the knowledge base will be considerably improved resulting in benefits for various engineering fields. Especially the quantitative consideration of real residual stress states for optimized component designs will be possible and after all the consequences of residual stresses on safety of components which are used in nuclear facilities can be evaluated. In this second experimental research chapter (phase 2) the findings of the first numerical and theoretical research chapter (phase 1) where proofed. The developed differential calculation method with the method of adaptive calibration functions were compared with the

  1. Space Tourism: Orbital Debris Considerations

    Science.gov (United States)

    Mahmoudian, N.; Shajiee, S.; Moghani, T.; Bahrami, M.

    2002-01-01

    Space activities after a phase of research and development, political competition and national prestige have entered an era of real commercialization. Remote sensing, earth observation, and communication are among the areas in which this growing industry is facing competition and declining government money. A project like International Space Station, which draws from public money, has not only opened a window of real multinational cooperation, but also changed space travel from a mere fantasy into a real world activity. Besides research activities for sending man to moon and Mars and other outer planets, space travel has attracted a considerable attention in recent years in the form of space tourism. Four countries from space fairing nations are actively involved in the development of space tourism. Even, nations which are either in early stages of space technology development or just beginning their space activities, have high ambitions in this area. This is worth noting considering their limited resources. At present, trips to space are available, but limited and expensive. To move beyond this point to generally available trips to orbit and week long stays in LEO, in orbital hotels, some of the required basic transportations, living requirements, and technological developments required for long stay in orbit are already underway. For tourism to develop to a real everyday business, not only the price has to come down to meaningful levels, but also safety considerations should be fully developed to attract travelers' trust. A serious hazard to space activities in general and space tourism in particular is space debris in earth orbit. Orbiting debris are man-made objects left over by space operations, hazardous to space missions. Since the higher density of debris population occurs in low earth orbit, which is also the same orbit of interest to space tourism, a careful attention should be paid to the effect of debris on tourism activities. In this study, after a

  2. Ethical considerations for field research on fishes

    Directory of Open Access Journals (Sweden)

    Rhett H. Bennett

    2016-12-01

    Full Text Available Collection of data from animals for research purposes can negatively impact target or by-catch species if suitable animal ethics practices are not followed. This study aimed to assess the ethical requirements of peer-reviewed scientific journals that publish primary literature on fishes, and review the ethical considerations and animal care guidelines of national and international documents on the ethical treatment of animals for research, to provide an overview of the general ethical considerations for field research on fishes. A review of 250 peer-reviewed, ISI-rated journals publishing primary research on fishes revealed that nearly half (46% had no mention of ethics, treatment of animals or ethical requirements for publication in their author guidelines or publication policies. However, 18% of the journals reviewed identify a specific set of ethical guidelines to be followed before publishing research involving animals. Ethical considerations for investigators undertaking field research on fishes, common to most animal care policies, legislation and guiding documents, include adhering to relevant legislation, minimising sample sizes, reducing or mitigating pain and distress, employing the most appropriate and least invasive techniques and accurately reporting methods and findings. This information will provide potential investigators with a useful starting point for designing and conducting ethical field research. Application of ethical best practices in field sampling studies will improve the welfare of study animals and the conservation of rare and endangered species. Conservation implications: This article provides a list of ethical considerations for designing and conducting field research on fishes. By reviewing sampling techniques and processes that are frequently used in field research on fishes and by highlighting the potential negative impacts of these sampling techniques, this article is intended to assist researchers in planning

  3. TRIGA reactor health physics considerations

    International Nuclear Information System (INIS)

    Johnson, A.G.

    1970-01-01

    The factors influencing the complexity of a TRIGA health physics program are discussed in details in order to serve as a basis for later consideration of various specific aspects of a typical TRIGA health physics program. The health physics program must be able to provide adequate assistance, control, and safety for individuals ranging from the inexperienced student to the experienced postgraduate researcher. Some of the major aspects discussed are: effluent release and control; reactor area air monitoring; area monitoring; adjacent facilities monitoring; portable instrumentation, personnel monitoring. TRIGA reactors have not been associated with many significant occurrences in the area of health physics, although some operational occurrences have had health physics implications. One specific occurrence at OSU is described involving the detection of non-fission-product radioactive particulates by the continuous air monitor on the reactor top. The studies of this particular situation indicate that most of the particulate activity is coming from the rotating rack and exhausting to the reactor top through the rotating rack loading tube

  4. Hypochondriasis: considerations for ICD-11

    Directory of Open Access Journals (Sweden)

    Odile A. van den Heuvel

    2014-01-01

    Full Text Available The World Health Organization (WHO is currently revisiting the ICD. In the 10th version of the ICD, approved in 1990, hypochondriacal symptoms are described in the context of both the primary condition hypochondriacal disorder and as secondary symptoms within a range of other mental disorders. Expansion of the research base since 1990 makes a critical evaluation and revision of both the definition and classification of hypochondriacal disorder timely. This article addresses the considerations reviewed by members of the WHO ICD-11 Working Group on the Classification of Obsessive-Compulsive and Related Disorders in their proposal for the description and classification of hypochondriasis. The proposed revision emphasizes the phenomenological overlap with both anxiety disorders (e.g., fear, hypervigilance to bodily symptoms, and avoidance and obsessive-compulsive and related disorders (e.g., preoccupation and repetitive behaviors and the distinction from the somatoform disorders (presence of somatic symptom is not a critical characteristic. This revision aims to improve clinical utility by enabling better recognition and treatment of patients with hypochondriasis within the broad range of global health care settings.

  5. MARKETING CONSIDERATIONS ON BRAND COMMUNITIES

    Directory of Open Access Journals (Sweden)

    A.-C. Budac

    2016-12-01

    Full Text Available Most consumers spend an important part of their free time looking for online information about the brands before taking a decision to purchase. The Internet is the main factor which has led to a considerable increase of the time allotted by consumers for search and comparing information about brands, as a step preceding the decision to purchase and also one of the most important factors that influence the interaction between the brand and the consumer. Although the general trend is that the public to become more active and more involved in the choice of the brand, consumer's responses to its messages obviously depend on cultural, social or economic factors. The work has the purpose to clarify what brand community means and how it appeared - if it was really built from scratch or it has already existed in a latent way and it must only be recognized - the characteristics of successful communities, which of the objectives of the brands can be achieved by means of these groups, what is the role of social media in the development of these communities, what kind of types of mem¬bers are likely to be encountered inside of the online communities and what is their proportion for each and which are the research methodologies that can give support to companies in monitoring these groups.

  6. Ethical Considerations of Preclinical Testing

    Directory of Open Access Journals (Sweden)

    Allen Goldenthal

    2015-12-01

    Full Text Available The numbers of animal tests being conducted are on a sharp incline.  Much of this increase is directly due to our ability to generate transgenic models and knock-outs, thereby increasing the validity of the animal model but not necessarily correlating directly with any translational medical benefits to the human counterpart.  In spite of our best efforts, there still exist species differences that prevent the application directly from animal to human, and in some examples having a completely different and adverse effect from that seen in the animal model. There are several ways in which we can improve the opportunity for a positive test outcome and at the same time reduce the animal usage which is associated with our current animal testing practices. The benefit of the 3R’s is that they encourage us not only to avoid wastage of life but that they require us to provide considerable foresight and extrapolated thought before directly engaging in the preclinical testing phase.

  7. CONSIDERATIONS ON CONSUMER PERCEIVED RISK

    Directory of Open Access Journals (Sweden)

    Laura Catalina Timiras

    2014-12-01

    Full Text Available In this article we identified a number of factors influencing the consumers’ perceived risk. In the first part we conducted a review of the main issues that define the perceived risk by the consumer at the time of purchase, some of the lines of action of the organizations to diminish this risk perception and a number of influencing factors presented in the literature, with significant impact on the intensity with which risk is perceived by consumers. The second part of the article is based on the statistical information regarding e-commerce market, market in which the perceived risk plays an important role in the purchasing decision. Thus, based on available official statistics provided by Eurostat we have revealed the existence of certain links between electronic commerce and orientation towards risk and income levels, age and consumer educational level. The review is not intended to be exhaustive, the study taking into consideration only those links that can be identified from using official statistical data.

  8. Considerations regarding dosimetry in children

    International Nuclear Information System (INIS)

    Gilday, D.L.

    1986-01-01

    The most important consideration when deciding whether or not to perform a nuclear medicine procedure in a child is whether the benefit of the information obtained exceeds the potential risk. In most circumstances the potential benefits are well define. No patient should be studied unless the question to be answered is clearly understood and there is a reasonable change to answer it. To properly perform procedures in children one must not only have a schedule to scale the radiopharmaceutical dose to be administered to the child's body surface area but also one must have an established minimum dose for small babies and infants. There is no point in under-dosing the patient as then the information will not be obtained from the nuclear medicine society. The value of nuclear medicine in the pediatric population cannot be underestimated. It is often the single most important test that can be performed diagnostically. For these reasons it is very important to understand the proper relationship of an adequate study versus the minimization of radiation. 3 references

  9. Enabling fast charging - Vehicle considerations

    Science.gov (United States)

    Meintz, Andrew; Zhang, Jiucai; Vijayagopal, Ram; Kreutzer, Cory; Ahmed, Shabbir; Bloom, Ira; Burnham, Andrew; Carlson, Richard B.; Dias, Fernando; Dufek, Eric J.; Francfort, James; Hardy, Keith; Jansen, Andrew N.; Keyser, Matthew; Markel, Anthony; Michelbacher, Christopher; Mohanpurkar, Manish; Pesaran, Ahmad; Scoffield, Don; Shirk, Matthew; Stephens, Thomas; Tanim, Tanvir

    2017-11-01

    To achieve a successful increase in the plug-in battery electric vehicle (BEV) market, it is anticipated that a significant improvement in battery performance is required to increase the range that BEVs can travel and the rate at which they can be recharged. While the range that BEVs can travel on a single recharge is improving, the recharge rate is still much slower than the refueling rate of conventional internal combustion engine vehicles. To achieve comparable recharge times, we explore the vehicle considerations of charge rates of at least 400 kW. Faster recharge is expected to significantly mitigate the perceived deficiencies for long-distance transportation, to provide alternative charging in densely populated areas where overnight charging at home may not be possible, and to reduce range anxiety for travel within a city when unplanned charging may be required. This substantial increase in charging rate is expected to create technical issues in the design of the battery system and the vehicle's electrical architecture that must be resolved. This work focuses on vehicle system design and total recharge time to meet the goals of implementing improved charge rates and the impacts of these expected increases on system voltage and vehicle components.

  10. Euthanasia of Cattle: Practical Considerations and Application.

    Science.gov (United States)

    Shearer, Jan Keith

    2018-04-17

    Acceptable methods for the euthanasia of cattle include overdose of an anesthetic, gunshot and captive bolt. The use of anesthetics for euthanasia is costly and complicates carcass disposal. These issues can be avoided by use of a physical method such as gunshot or captive bolt; however, each requires that certain conditions be met to assure an immediate loss of consciousness and death. For example, the caliber of firearm and type of bullet are important considerations when gunshot is used. When captive bolt is used, a penetrating captive bolt loaded with the appropriate powder charge and accompanied by a follow up (adjunctive) step to assure death are required. The success of physical methods also requires careful selection of the anatomic site for entry of a “free bullet” or “bolt” in the case of penetrating captive bolt. Disease eradication plans for animal health emergencies necessitate methods of euthanasia that will facilitate rapid and efficient depopulation of animals while preserving their welfare to the greatest extent possible. A portable pneumatic captive bolt device has been developed and validated as effective for use in mass depopulation scenarios. Finally, while most tend to focus on the technical aspects of euthanasia, it is extremely important that no one forget the human cost for those who may be required to perform the task of euthanasia on a regular basis. Symptoms including depression, grief, sleeplessness and destructive behaviors including alcoholism and drug abuse are not uncommon for those who participate in the euthanasia of animals.

  11. Euthanasia of Cattle: Practical Considerations and Application

    Directory of Open Access Journals (Sweden)

    Jan Keith Shearer

    2018-04-01

    Full Text Available Acceptable methods for the euthanasia of cattle include overdose of an anesthetic, gunshot and captive bolt. The use of anesthetics for euthanasia is costly and complicates carcass disposal. These issues can be avoided by use of a physical method such as gunshot or captive bolt; however, each requires that certain conditions be met to assure an immediate loss of consciousness and death. For example, the caliber of firearm and type of bullet are important considerations when gunshot is used. When captive bolt is used, a penetrating captive bolt loaded with the appropriate powder charge and accompanied by a follow up (adjunctive step to assure death are required. The success of physical methods also requires careful selection of the anatomic site for entry of a “free bullet” or “bolt” in the case of penetrating captive bolt. Disease eradication plans for animal health emergencies necessitate methods of euthanasia that will facilitate rapid and efficient depopulation of animals while preserving their welfare to the greatest extent possible. A portable pneumatic captive bolt device has been developed and validated as effective for use in mass depopulation scenarios. Finally, while most tend to focus on the technical aspects of euthanasia, it is extremely important that no one forget the human cost for those who may be required to perform the task of euthanasia on a regular basis. Symptoms including depression, grief, sleeplessness and destructive behaviors including alcoholism and drug abuse are not uncommon for those who participate in the euthanasia of animals.

  12. Some considerations on stochastic neutron populations (u)

    International Nuclear Information System (INIS)

    Souto, Francisco J.; Prinja, Anil K.

    2010-01-01

    The neutron population in a multiplying body containing a weak random source may depart considerably from its average or expected value. The resulting behavior of the system is then unpredictable and a fully stochastic description of the neutron population becomes necessary. Stochastic considerations are especially important when dealing with pulsed reactors or in the case of criticality excursions in the presence of a weak source. Using the theory of discrete-state continuous-time Markov processes, and subject to some physical approximations, Bell (I) obtained approximate solutions for the neutron number probability distributions (pdf), with and without an intrinsic rapdom neutron source, that were valid at late times and/ large neutron populations. In recent work (4), we obtained exact solutions for Bell's model problem, and in this paper we use these exact probability distributions to: (I) assess the accuracy of Bell's asymptotic solutions and show how the latter follow from the exact solutions, (2) rigorously examine the probability of obtaining a divergent chain reaction, and (3) demonstrate the existence of an abrupt transition from a stochastic to a deterministic phase with increasing source strength.

  13. Orthodontic Treatment Consideration in Diabetic Patients.

    Science.gov (United States)

    Almadih, Ahmed; Al-Zayer, Maryam; Dabel, Sukainh; Alkhalaf, Ahmed; Al Mayyad, Ali; Bardisi, Wajdi; Alshammari, Shouq; Alsihati, Zainab

    2018-02-01

    Although orthodontic treatment is commonly indicated for young healthy individuals, recent trends showed an increase in number of older individuals undergoing orthodontic interventions. The increased age resulted in a proportionate increase in the prevalence of systemic diseases facing dentists during orthodontic procedures, especially diabetes mellitus. This necessitates that dentists should be aware of the diagnosis of diabetes mellitus and its early signs particularly in teeth and oral cavity. It is also essential for them to understand the implications of diabetes on orthodontic treatment and the measures to be considered during managing those patients. In this review, we focused on the impact of diabetes mellitus on orthodontic treatment. We also summarized the data from previous studies that had explained the measures required to be taken into consideration during managing those patients. We included both human and animal studies to review in depth the pathophysiological mechanisms by which diabetes affects orthodontic treatment outcome. In conclusion, this review emphasizes the need to carefully identify early signs and symptoms of diabetes mellitus in patients demanding orthodontic treatment and to understand the considerations to be adopted before and during treating these patients.

  14. Game theoretic considerations for Kenyan health governance ...

    African Journals Online (AJOL)

    Game theoretic considerations for Kenyan health governance. ... theoretic considerations in their practice in order to achieve market-driven competition ... Key words: Game theory, social capital, good governance, health policy, health systems.

  15. UV Photography Shows Hidden Sun Damage

    Science.gov (United States)

    ... mcat1=de12", ]; for (var c = 0; c UV photography shows hidden sun damage A UV photograph gives ... developing skin cancer and prematurely aged skin. Normal photography UV photography 18 months of age: This boy's ...

  16. Considerations about our approach to obstetric psychoprophylaxis.

    Science.gov (United States)

    Cerutti, R; Volpe, B; Sichel, M P; Sandri, M; Sbrignadello, C; Fede, T

    1983-01-01

    Usually the term "obstetric psychoprophylaxis" refers to a specific method or technique. We prefer to consider it as a procedure that involves on one side the woman, the child and its family, and on the other the services entitled to give pre- and post-natal assistance. In order to realize this, a reformation of our methodological parameters and a critical analysis of the results obtained are required. In the courses of obstetric psychoprophylaxis that are held in the Department of Obstetrics and Gynaecology of the University of Padua we take into consideration the following themes: - Methodological approach - Professional training of the staff - Significance of psychosocial culture in the management of the pregnancy by the health services.

  17. Performance Assessment of Water Sectors : Methods and considerations for application

    NARCIS (Netherlands)

    Wieriks, M.

    2011-01-01

    With the rise of principles for water management in the 1990’s such as concepts as Integrated Water Resources Management (IWRM) and Integrated River Basin Management (IRBM), many countries have come to review their water policy and sectors. But how does one start in the assessment of a water sector

  18. Considerations regarding nuclear medicine terminology

    International Nuclear Information System (INIS)

    Als, C.

    2008-01-01

    This article through some examples shows us all the interest of the use of terminology in nuclear medicine. Each would find in it its interest, from the patient to the doctors in different disciplines. (N.C.)

  19. 32 CFR 643.74 - Consideration.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 4 2010-07-01 2010-07-01 true Consideration. 643.74 Section 643.74 National... Licenses § 643.74 Consideration. When a license is granted under the authority of an easement or leasing statute, the same rules will apply in regard to consideration as is applicable to the granting of an...

  20. 5 CFR 330.206 - Job consideration.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Job consideration. 330.206 Section 330..., SELECTION, AND PLACEMENT (GENERAL) Reemployment Priority List (RPL) § 330.206 Job consideration. (a)(1) An eligible employee under § 330.203 is entitled to consideration for positions in the commuting area for...

  1. 32 CFR 643.53 - Consideration.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 4 2010-07-01 2010-07-01 true Consideration. 643.53 Section 643.53 National... Leases § 643.53 Consideration. (a) Unless otherwise authorized by this regulation or directed by the SA, the consideration for a lease of real estate will be the appraised fair market rental value. However...

  2. 15 CFR 2301.5 - Special consideration.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 3 2010-01-01 2010-01-01 false Special consideration. 2301.5 Section... PROGRAM Application Requirements § 2301.5 Special consideration. In accordance with section 392(f) of the Act, the Agency will give special consideration to applications that foster ownership of, operation of...

  3. 46 CFR 169.112 - Special consideration.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Special consideration. 169.112 Section 169.112 Shipping... Provisions § 169.112 Special consideration. In applying the provisions of this part, the Officer in Charge, Marine Inspection, may give special consideration to departures from the specific requirements when...

  4. 49 CFR 260.7 - Priority consideration.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Priority consideration. 260.7 Section 260.7... REHABILITATION AND IMPROVEMENT FINANCING PROGRAM Overview § 260.7 Priority consideration. When evaluating applications, the Administrator will give priority consideration (but not necessarily in the following order...

  5. 46 CFR 175.550 - Special consideration.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Special consideration. 175.550 Section 175.550 Shipping...) GENERAL PROVISIONS § 175.550 Special consideration. In applying the provisions of this subchapter, the OCMI may give special consideration to authorizing departures from the specific requirements when...

  6. The Bradford Hill considerations on causality: a counterfactual perspective

    Directory of Open Access Journals (Sweden)

    Höfler Michael

    2005-11-01

    Full Text Available Abstract Bradford Hill's considerations published in 1965 had an enormous influence on attempts to separate causal from non-causal explanations of observed associations. These considerations were often applied as a checklist of criteria, although they were by no means intended to be used in this way by Hill himself. Hill, however, avoided defining explicitly what he meant by "causal effect". This paper provides a fresh point of view on Hill's considerations from the perspective of counterfactual causality. I argue that counterfactual arguments strongly contribute to the question of when to apply the Hill considerations. Some of the considerations, however, involve many counterfactuals in a broader causal system, and their heuristic value decreases as the complexity of a system increases; the danger of misapplying them can be high. The impacts of these insights for study design and data analysis are discussed. The key analysis tool to assess the applicability of Hill's considerations is multiple bias modelling (Bayesian methods and Monte Carlo sensitivity analysis; these methods should be used much more frequently.

  7. Educational Outreach: The Space Science Road Show

    Science.gov (United States)

    Cox, N. L. J.

    2002-01-01

    The poster presented will give an overview of a study towards a "Space Road Show". The topic of this show is space science. The target group is adolescents, aged 12 to 15, at Dutch high schools. The show and its accompanying experiments would be supported with suitable educational material. Science teachers at schools can decide for themselves if they want to use this material in advance, afterwards or not at all. The aims of this outreach effort are: to motivate students for space science and engineering, to help them understand the importance of (space) research, to give them a positive feeling about the possibilities offered by space and in the process give them useful knowledge on space basics. The show revolves around three main themes: applications, science and society. First the students will get some historical background on the importance of space/astronomy to civilization. Secondly they will learn more about novel uses of space. On the one hand they will learn of "Views on Earth" involving technologies like Remote Sensing (or Spying), Communication, Broadcasting, GPS and Telemedicine. On the other hand they will experience "Views on Space" illustrated by past, present and future space research missions, like the space exploration missions (Cassini/Huygens, Mars Express and Rosetta) and the astronomy missions (Soho and XMM). Meanwhile, the students will learn more about the technology of launchers and satellites needed to accomplish these space missions. Throughout the show and especially towards the end attention will be paid to the third theme "Why go to space"? Other reasons for people to get into space will be explored. An important question in this is the commercial (manned) exploration of space. Thus, the questions of benefit of space to society are integrated in the entire show. It raises some fundamental questions about the effects of space travel on our environment, poverty and other moral issues. The show attempts to connect scientific with

  8. Consideration of aging in probabilistic safety assessment

    International Nuclear Information System (INIS)

    Titina, B.; Cepin, M.

    2007-01-01

    Probabilistic safety assessment is a standardised tool for assessment of safety of nuclear power plants. It is a complement to the safety analyses. Standard probabilistic models of safety equipment assume component failure rate as a constant. Ageing of systems, structures and components can theoretically be included in new age-dependent probabilistic safety assessment, which generally causes the failure rate to be a function of age. New age-dependent probabilistic safety assessment models, which offer explicit calculation of the ageing effects, are developed. Several groups of components are considered which require their unique models: e.g. operating components e.g. stand-by components. The developed models on the component level are inserted into the models of the probabilistic safety assessment in order that the ageing effects are evaluated for complete systems. The preliminary results show that the lack of necessary data for consideration of ageing causes highly uncertain models and consequently the results. (author)

  9. Transplanting the Body: Preliminary Ethical Considerations.

    Science.gov (United States)

    Miller, Lantz Fleming

    2017-11-01

    A dissociated area of medical research warrants bioethical consideration: a proposed transplantation of a donor's entire body, except head, to a patient with a fatal degenerative disease. The seeming improbability of such an operation can only underscore the need for thorough bioethical assessment: Not assessing a case of such potential ethical import, by showing neglect instead of facing the issue, can only compound the ethical predicament, perhaps eroding public trust in ethical medicine. This article discusses the historical background of full-body transplantation, documents the seriousness of its current pursuit, and builds an argument for why prima facie this type of transplant is bioethically distinct. Certainly, this examination can only be preliminary, indicating what should be a wide and vigorous discussion among practitioners and ethicists. It concludes with practical suggestions for how the medical and bioethics community may proceed with ethical assessment.

  10. 2008 LHC Open Days Physics: the show

    CERN Multimedia

    2008-01-01

    A host of events and activities await visitors to the LHC Open Days on 5 and 6 April. A highlight will be the physics shows funded by the European Physical Society (EPS), which are set to surprise and challenge children and adults alike! School children use their experience of riding a bicycle to understand how planets move around the sun (Copyright : Circus Naturally) Participating in the Circus Naturally show could leave a strange taste in your mouth! (Copyright : Circus Naturally) The Rino Foundation’s experiments with liquid nitrogen can be pretty exciting! (Copyright: The Rino Foundation)What does a bicycle have in common with the solar system? Have you ever tried to weigh air or visualise sound? Ever heard of a vacuum bazooka? If you want to discover the answers to these questions and more then come to the Physics Shows taking place at the CERN O...

  11. Online Italian fandoms of American TV shows

    Directory of Open Access Journals (Sweden)

    Eleonora Benecchi

    2015-06-01

    Full Text Available The Internet has changed media fandom in two main ways: it helps fans connect with each other despite physical distance, leading to the formation of international fan communities; and it helps fans connect with the creators of the TV show, deepening the relationship between TV producers and international fandoms. To assess whether Italian fan communities active online are indeed part of transnational online communities and whether the Internet has actually altered their relationship with the creators of the original text they are devoted to, qualitative analysis and narrative interviews of 26 Italian fans of American TV shows were conducted to explore the fan-producer relationship. Results indicated that the online Italian fans surveyed preferred to stay local, rather than using geography-leveling online tools. Further, the sampled Italian fans' relationships with the show runners were mediated or even absent.

  12. Playware Research – Methodological Considerations

    DEFF Research Database (Denmark)

    Lund, Henrik Hautop

    2014-01-01

    Several sub-disciplines of engineering are driven by the researchers’ aim of providing positive change to the society through their engineering. These researchers are challenged by the traditional research method of experimental research with a waterfall model which demands clearly defined projec...... characterized by rapid prototyping cycles which allow iterative technology specification and development together with people in their real world environment....

  13. Considerations for ceramic inlays in posterior teeth: a review

    Science.gov (United States)

    Hopp, Christa D; Land, Martin F

    2013-01-01

    This review of ceramic inlays in posterior teeth includes a review of the history of ceramic restorations, followed by common indications and contraindications for their use. A discussion on the potential for tooth wear is followed by a review of recommended preparation design considerations, fabrication methods, and material choices. Despite the improved materials available for fabrication of porcelain inlays, fracture remains a primary mode of inlay failure. Therefore, a brief discussion on strengthening methods for ceramics is included. The review concludes with a section on luting considerations, and offers the clinician specific recommendations for luting procedures. In conclusion, inlay success rates and longevity, as reported in the literature, are summarized. PMID:23750101

  14. Duchenne muscular dystrophy models show their age

    OpenAIRE

    Chamberlain, Jeffrey S.

    2010-01-01

    The lack of appropriate animal models has hampered efforts to develop therapies for Duchenne muscular dystrophy (DMD). A new mouse model lacking both dystrophin and telomerase (Sacco et al., 2010) closely mimics the pathological progression of human DMD and shows that muscle stem cell activity is a key determinant of disease severity.

  15. Show Them You Really Want the Job

    Science.gov (United States)

    Perlmutter, David D.

    2012-01-01

    Showing that one really "wants" the job entails more than just really wanting the job. An interview is part Broadway casting call, part intellectual dating game, part personality test, and part, well, job interview. When there are 300 applicants for a position, many of them will "fit" the required (and even the preferred) skills listed in the job…

  16. A Talk Show from the Past.

    Science.gov (United States)

    Gallagher, Arlene F.

    1991-01-01

    Describes a two-day activity in which elementary students examine voting rights, the right to assemble, and women's suffrage. Explains the game, "Assemble, Reassemble," and a student-produced talk show with five students playing the roles of leaders of the women's suffrage movement. Profiles Elizabeth Cady Stanton, Lucretia Mott, Susan…

  17. Laser entertainment and light shows in education

    Science.gov (United States)

    Sabaratnam, Andrew T.; Symons, Charles

    2002-05-01

    Laser shows and beam effects have been a source of entertainment since its first public performance May 9, 1969, at Mills College in Oakland, California. Since 1997, the Photonics Center, NgeeAnn Polytechnic, Singapore, has been using laser shows as a teaching tool. Students are able to exhibit their creative skills and learn at the same time how lasers are used in the entertainment industry. Students will acquire a number of skills including handling three- phase power supply, operation of cooling system, and laser alignment. Students also acquire an appreciation of the arts, learning about shapes and contours as they develop graphics for the shows. After holography, laser show animation provides a combination of the arts and technology. This paper aims to briefly describe how a krypton-argon laser, galvanometer scanners, a polychromatic acousto-optic modulator and related electronics are put together to develop a laser projector. The paper also describes how students are trained to make their own laser animation and beam effects with music, and at the same time have an appreciation of the operation of a Class IV laser and the handling of optical components.

  18. The Last Great American Picture Show

    NARCIS (Netherlands)

    Elsaesser, Thomas; King, Noel; Horwath, Alexander

    2004-01-01

    The Last Great American Picture Show brings together essays by scholars and writers who chart the changing evaluations of the American cinema of the 1970s, sometimes referred to as the decade of the lost generation, but now more and more recognized as the first New Hollywood, without which the

  19. Considerations for reference pump curves

    International Nuclear Information System (INIS)

    Stockton, N.B.

    1992-01-01

    This paper examines problems associated with inservice testing (IST) of pumps to assess their hydraulic performance using reference pump curves to establish acceptance criteria. Safety-related pumps at nuclear power plants are tested under the American Society of Mechanical Engineers (ASME) Boiler and Pressure Vessel Code (the Code), Section 11. The Code requires testing pumps at specific reference points of differential pressure or flow rate that can be readily duplicated during subsequent tests. There are many cases where test conditions cannot be duplicated. For some pumps, such as service water or component cooling pumps, the flow rate at any time depends on plant conditions and the arrangement of multiple independent and constantly changing loads. System conditions cannot be controlled to duplicate a specific reference value. In these cases, utilities frequently request to use pump curves for comparison of test data for acceptance. There is no prescribed method for developing a pump reference curve. The methods vary and may yield substantially different results. Some results are conservative when compared to the Code requirements; some are not. The errors associated with different curve testing techniques should be understood and controlled within reasonable bounds. Manufacturer's pump curves, in general, are not sufficiently accurate to use as reference pump curves for IST. Testing using reference curves generated with polynomial least squares fits over limited ranges of pump operation, cubic spline interpolation, or cubic spline least squares fits can provide a measure of pump hydraulic performance that is at least as accurate as the Code required method. Regardless of the test method, error can be reduced by using more accurate instruments, by correcting for systematic errors, by increasing the number of data points, and by taking repetitive measurements at each data point

  20. Reality, ficción o show

    Directory of Open Access Journals (Sweden)

    Sandra Ruíz Moreno

    2002-01-01

    Full Text Available Para tener un punto de vista claro y objetivo frente a la polémica establecida en torno al programa “Protagonistas de novela” y la tendiente proliferación de los reality show en las parrillas de programación de la televisión colombiana, se realizó un análisis de texto y contenido de dicho programa, intentando definirlo desde sus posibilidades de realidad, ficción y show. Las unidades de análisis y el estudio de su tratamiento arrojaron un alto contenido que gira en torno a las emociones del ser humano relacionadas con la convivencia, tratadas a manera de show y con algunos aportes textuales de ficción, pero sin su elemento mediador básico, el actor, quitándole toda la posibilidad de tener un tratamiento con la profundidad, distancia y ética que requieren los temas de esta índole. El resultado es un formato que sólo busca altos índices de sintonía y que pertenece más a la denominada televisión “trash”, que a una búsqueda de realidad del hombre y mucho menos de sociedad.

  1. Considerations on an inland rectenna

    Energy Technology Data Exchange (ETDEWEB)

    Itoh, Kiyohiko; Ogawa, Yasutaka

    1988-01-01

    An earth terminal 'rectenna' is one of the essential elements of a solar power satellite system. This paper considers, some aspects of an inland rectenna. First, we show that an inland rectenna has advantages over an offshore one. Then we describe the inland rectenna and an associated artificial city. Moreover, the hogline rectenna and modified hogline rectenna with circular microstrip antennae are discussed, and several expressions are obtained which will be useful for designing the hogline type rectenna.

  2. Integral fast reactor shows its mettle

    International Nuclear Information System (INIS)

    Chang, Ya.; Lajnberri, M.; Barris, L.; Uoters, L.

    1988-01-01

    The main aspects of the problem of developing a closed fuel cycle at a NPP built in the so-called integrated version when a fast reactor and the plant for spent fuel regeneration and fuel element production are located in the same site (IFR project), are considered. The technologies of U-Pu-Zr alloy fuel reprocessing and production based on high-temperature metallurgical process and the method of casting under pressure are described. The demonstration of practical feasibility of the fuel cycle on the basis of the IFR reactor is planned for 1990

  3. Photovoltaic power system reliability considerations

    Science.gov (United States)

    Lalli, V. R.

    1980-01-01

    This paper describes an example of how modern engineering and safety techniques can be used to assure the reliable and safe operation of photovoltaic power systems. This particular application was for a solar cell power system demonstration project in Tangaye, Upper Volta, Africa. The techniques involve a definition of the power system natural and operating environment, use of design criteria and analysis techniques, an awareness of potential problems via the inherent reliability and FMEA methods, and use of a fail-safe and planned spare parts engineering philosophy.

  4. Considerations in the public acceptance of sewage sludge irradiation systems

    International Nuclear Information System (INIS)

    Dix, G.P.

    1975-01-01

    Considerations associated with public acceptance of municipal sewage sludge irradiation systems are discussed including the benefit to society, public information and safeguards. Public acceptance of products is based upon the benefit to society as measured by reduced consumer costs, minimization of public risk and enhancement of the quality of life and the environment. When viewed in this positive light, the sludge irradiator has high potential benefits to the community. If large-scale engineering experiments show that sludge irradiation is more cost-effective than other methods, reduced consumer costs would result. Today many sewage plants do not consistently remove pathogens from sludge; sludge irradiation could be an effective method of pathogen removal and result in avoidance of a major public risk. The sludge irradiator may be able to clean up recreational areas, reduce noxious odours from sewage treatment facilities, and reduce the energy requirements for producing fertilizer and soil conditioners and conserve their mineral content. Plant safeguards must be explained to dispel public concern that the contents of the source can be released to the sludge accidentally. This will be the main issue within the technical sector of the public, and the design, procedural and administrative safeguards of the plant must be fully explained. The primary risk associated with sludge irradiators will be the remote possibility of source leakage into the sludge. The various safeguards in sludge irradiation plants are discussed in detail including the form of the radionuclide, encapsulation, the irradiation chamber, safeguards instrumentation, shielding and thermal safeguards. (Author)

  5. Lane-changing model with dynamic consideration of driver's propensity

    Science.gov (United States)

    Wang, Xiaoyuan; Wang, Jianqiang; Zhang, Jinglei; Ban, Xuegang Jeff

    2015-07-01

    Lane-changing is the driver's selection result of the satisfaction degree in different lane driving conditions. There are many different factors influencing lane-changing behavior, such as diversity, randomicity and difficulty of measurement. So it is hard to accurately reflect the uncertainty of drivers' lane-changing behavior. As a result, the research of lane-changing models is behind that of car-following models. Driver's propensity is her/his emotion state or the corresponding preference of a decision or action toward the real objective traffic situations under the influence of various dynamic factors. It represents the psychological characteristics of the driver in the process of vehicle operation and movement. It is an important factor to influence lane-changing. In this paper, dynamic recognition of driver's propensity is considered during simulation based on its time-varying discipline and the analysis of the driver's psycho-physic characteristics. The Analytic Hierarchy Process (AHP) method is used to quantify the hierarchy of driver's dynamic lane-changing decision-making process, especially the influence of the propensity. The model is validated using real data. Test results show that the developed lane-changing model with the dynamic consideration of a driver's time-varying propensity and the AHP method are feasible and with improved accuracy.

  6. Technical considerations in nuclear terrorism

    International Nuclear Information System (INIS)

    Velardo, G.

    2007-01-01

    Nuclear terrorism is an evil application of nuclear energy, in the same way that chemical and biological terrorism could be considered as the evil side of chemistry and biology. This paper presents two effects of nuclear terrorism. First, dirty bombs or radioactive bombs or radiological dispersion devices (RDDs), and second, crude atom bombs or improvised nuclear devices (INDs). The paper analyses as well the probabilities of an attack, its biological effects and nuclear risk. Experiments carried out so far indicate that the lethal effects produced by RDDs are likely the same that the effects produced by the chemical explosive used in the bomb. These type of bombs are rather bounded to generate panic and have implicit a high cost of decontamination. It will be described the measures to be adopted. INDs will be also considered. Uranium INDs by gun-method are more feasible to be made. They can be disassembled and their components transported to the target place. Plutonium INDs by the implosion-method are complex and required high precision technology. Their disassembly is very difficult

  7. Ecological Considerations on Nickel Dermatitis

    Science.gov (United States)

    Marcussen, Poul V.

    1960-01-01

    The incidence of nickel dermatoses has shifted from the plating industry to other occupations and particularly to non-occupational causes. A Danish survey of 621 cases shows that 4% are due to nickel plating, 9·5% to other occupations, and 86·5% were not due to occupation. A primary eruption not due to occupation had occurred in 14% of the occupational cases. The importance of preventive measures for the community more than for the adequately controlled industry is underlined. PMID:14420983

  8. Transnasal endoscopy: Technical considerations, advantages and limitations.

    Science.gov (United States)

    Atar, Mustafa; Kadayifci, Abdurrahman

    2014-02-16

    Transnasal endoscopy (TNE) is an upper endoscopy method which is performed by the nasal route using a thin endoscope less than 6 mm in diameter. The primary goal of this method is to improve patient tolerance and convenience of the procedure. TNE can be performed without sedation and thus eliminates the risks associated with general anesthesia. In this way, TNE decreases the cost and total duration of endoscopic procedures, while maintaining the image quality of standard caliber endoscopes, providing good results for diagnostic purposes. However, the small working channel of the ultra-thin endoscope used for TNE makes it difficult to use for therapeutic procedures except in certain conditions which require a thinner endoscope. Biopsy is possible with special forceps less than 2 mm in diameter. Recently, TNE has been used for screening endoscopy in Far East Asia, including Japan. In most controlled studies, TNE was found to have better patient tolerance when compared to unsedated endoscopy. Nasal pain is the most significant symptom associated with endoscopic procedures but can be reduced with nasal pretreatment. Despite the potential advantage of TNE, it is not common in Western countries, usually due to a lack of training in the technique and a lack of awareness of its potential advantages. This paper briefly reviews the technical considerations as well as the potential advantages and limitations of TNE with ultra-thin scopes.

  9. Transnasal endoscopy: Technical considerations, advantages and limitations

    Science.gov (United States)

    Atar, Mustafa; Kadayifci, Abdurrahman

    2014-01-01

    Transnasal endoscopy (TNE) is an upper endoscopy method which is performed by the nasal route using a thin endoscope less than 6 mm in diameter. The primary goal of this method is to improve patient tolerance and convenience of the procedure. TNE can be performed without sedation and thus eliminates the risks associated with general anesthesia. In this way, TNE decreases the cost and total duration of endoscopic procedures, while maintaining the image quality of standard caliber endoscopes, providing good results for diagnostic purposes. However, the small working channel of the ultra-thin endoscope used for TNE makes it difficult to use for therapeutic procedures except in certain conditions which require a thinner endoscope. Biopsy is possible with special forceps less than 2 mm in diameter. Recently, TNE has been used for screening endoscopy in Far East Asia, including Japan. In most controlled studies, TNE was found to have better patient tolerance when compared to unsedated endoscopy. Nasal pain is the most significant symptom associated with endoscopic procedures but can be reduced with nasal pretreatment. Despite the potential advantage of TNE, it is not common in Western countries, usually due to a lack of training in the technique and a lack of awareness of its potential advantages. This paper briefly reviews the technical considerations as well as the potential advantages and limitations of TNE with ultra-thin scopes. PMID:24567791

  10. Ancient bacteria show evidence of DNA repair

    DEFF Research Database (Denmark)

    Johnson, Sarah Stewart; Hebsgaard, Martin B; Christensen, Torben R

    2007-01-01

    -term survival of bacteria sealed in frozen conditions for up to one million years. Our results show evidence of bacterial survival in samples up to half a million years in age, making this the oldest independently authenticated DNA to date obtained from viable cells. Additionally, we find strong evidence...... geological timescales. There has been no direct evidence in ancient microbes for the most likely mechanism, active DNA repair, or for the metabolic activity necessary to sustain it. In this paper, we couple PCR and enzymatic treatment of DNA with direct respiration measurements to investigate long...... that this long-term survival is closely tied to cellular metabolic activity and DNA repair that over time proves to be superior to dormancy as a mechanism in sustaining bacteria viability....

  11. Microbiological and environmental issues in show caves.

    Science.gov (United States)

    Saiz-Jimenez, Cesareo

    2012-07-01

    Cultural tourism expanded in the last half of the twentieth century, and the interest of visitors has come to include caves containing archaeological remains. Some show caves attracted mass tourism, and economical interests prevailed over conservation, which led to a deterioration of the subterranean environment and the rock art. The presence and the role of microorganisms in caves is a topic that is often ignored in cave management. Knowledge of the colonisation patterns, the dispersion mechanisms, and the effect on human health and, when present, over rock art paintings of these microorganisms is of the utmost importance. In this review the most recent advances in the study of microorganisms in caves are presented, together with the environmental implications of the findings.

  12. Extending Vulnerability Assessment to Include Life Stages Considerations.

    Science.gov (United States)

    Hodgson, Emma E; Essington, Timothy E; Kaplan, Isaac C

    2016-01-01

    Species are experiencing a suite of novel stressors from anthropogenic activities that have impacts at multiple scales. Vulnerability assessment is one tool to evaluate the likely impacts that these stressors pose to species so that high-vulnerability cases can be identified and prioritized for monitoring, protection, or mitigation. Commonly used semi-quantitative methods lack a framework to explicitly account for differences in exposure to stressors and organism responses across life stages. Here we propose a modification to commonly used spatial vulnerability assessment methods that includes such an approach, using ocean acidification in the California Current as an illustrative case study. Life stage considerations were included by assessing vulnerability of each life stage to ocean acidification and were used to estimate population vulnerability in two ways. We set population vulnerability equal to: (1) the maximum stage vulnerability and (2) a weighted mean across all stages, with weights calculated using Lefkovitch matrix models. Vulnerability was found to vary across life stages for the six species explored in this case study: two krill-Euphausia pacifica and Thysanoessa spinifera, pteropod-Limacina helicina, pink shrimp-Pandalus jordani, Dungeness crab-Metacarcinus magister and Pacific hake-Merluccius productus. The maximum vulnerability estimates ranged from larval to subadult and adult stages with no consistent stage having maximum vulnerability across species. Similarly, integrated vulnerability metrics varied greatly across species. A comparison showed that some species had vulnerabilities that were similar between the two metrics, while other species' vulnerabilities varied substantially between the two metrics. These differences primarily resulted from cases where the most vulnerable stage had a low relative weight. We compare these methods and explore circumstances where each method may be appropriate.

  13. ACCOUNTING FOR CONTINGENT CONSIDERATIONS IN BUSINESS COMBINATIONS

    OpenAIRE

    Gurgen KALASHYAN

    2017-01-01

    According to IFRS 3 Business Combinations contingent considerations must be included in the total consideration given for the acquired entity along with cash, other assets, ordinary or preference equity instruments, options, warrants. The contingent consideration is the determined amount which acquiring entity has to pay to acquired entity provided, that certain conditions will be fulfilled in the future. In case the provisions are not satisfied, we will get the situation when the amount of c...

  14. Some Metapsychological Considerations about Transference

    Directory of Open Access Journals (Sweden)

    Sergio Guillermo Castellanos-Urrego**

    2009-12-01

    Full Text Available This paper shows a metapsychological re-creation of transference from a conceptualization of representations as the units of psychism. Transferences have their origins in the effort of an unsatisfied libidinal investiture that continues to be active in the Unconscious, and which allows the primary process to inadvertently filter into the secondary process through a “false link”. Therefore, a current perception becomes identified with the expectative representation, which makes the individual believe that this new person will satisfy the aforementioned investiture. Transference neurosis is a psychoanalytic pillar, since only through it may one consciously and currently have access the repressed unconscious drives, a feature of childhood sexuality, and restart the psychosexual development.

  15. [Some considerations about aesthetic medicine].

    Science.gov (United States)

    Ferreira, Francisco Romão

    2010-01-01

    In this article, we will discuss some aspects of the construction of the meanings concerning the body from the scientific speech which was modeled based on modern thinking and became the hegemonic thinking of some sectors of the medical field. Meanings attributed to the body bring questions that come from other areas of the social life and those questions will build the aesthetic parameters which will be part of the identity construction, in the relation with the body itself, subjectivity and healthcare. We will describe some moments of the construction of the modern scientific thought and how this thought became hegemonic, influences the common sense, naturalizes identity construction and how dealing with the body, interferes in the healthcare, show a division among some sectors of the biomedicine, reinforce an specific type of medical rationality and makes an epistemic base and principle (theoretical and discursive) to some sectors connected to aesthetic medicine and aesthetic surgeries.

  16. Space Toxicology Challenges and Ethical Considerations

    Science.gov (United States)

    James, John T.

    2010-01-01

    Before delineating specific ways that nanotechnology enterprises might contribute to better management of toxicological risks during spaceflight, I will show how ethical considerations and several theories of justice can be applied to nanotechnology strategic plans. The principles that guide an ethical technical enterprise include autonomy, beneficence, non-maleficence, veracity and justice. Veracity (truth) is the underpinning principle; however, beyond this, proponents of nanotechnology must think carefully about balancing conflicting principles. For example, autonomy must yield to beneficence when fearful individuals simply lack knowledge to appreciate nanotechnology's beneficial advances. Justice is a complex topic upon which I will place six models: utilitarian, distributive, free-exchange/choice, individual dignity (social participation), equity vs. greed, and liberation of the poor. After briefly summarizing each model, I will present what I call an iterative-hybrid model of justice to show specifically how our thinking can be applied to nanotechnology enterprises. Within that broad landscape, I will discuss a single feature: how our early effort to understand health risks of carbon nanotubes fits into the iterative model. Finally, I will suggest ways that nanotechnology might advance our management of toxicological risks during spaceflight, but always with an eye toward how such advances might result in a more just world.

  17. Momentum considerations on the New MEXICO experiment

    Science.gov (United States)

    Parra, E. A.; Boorsma, K.; Schepers, J. G.; Snel, H.

    2016-09-01

    The present paper regards axial and angular momentum considerations combining detailed loads from pressure sensors and the flow field mapped with particle image velocimetry (PIV) techniques. For this end, the study implements important results leaning on experimental data from wind tunnel measurements of the New MEXICO project. The measurements, taken on a fully instrumented rotor, were carried out in the German Dutch Wind tunnel Organisation (DNW) testing the MEXICO rotor in the open section. The work revisits the so-called momentum theory, showing that the integral thrust and torque measured on the rotor correspond with an extent of 0.7 and 2.4% respectively to the momentum balance of the global flow field using the general momentum equations. Likewise, the sectional forces combined with the local induced velocities are found to plausibly obey the annular streamtube theory, albeit some limitations in the axial momentum become more apparent at high inductions after a=0.3. Finally, azimuth induced velocities are measured and compared to predictions from models of Glauert and Burton et al., showing close-matching forecasts for blade spans above 25%.

  18. 48 CFR 15.404-3 - Subcontract pricing considerations.

    Science.gov (United States)

    2010-10-01

    ... CONTRACTING METHODS AND CONTRACT TYPES CONTRACTING BY NEGOTIATION Contract Pricing 15.404-3 Subcontract pricing considerations. (a) The contracting officer is responsible for the determination of a fair and... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Subcontract pricing...

  19. 5 CFR 302.304 - Order of consideration.

    Science.gov (United States)

    2010-01-01

    ... her right of appeal to the Merit Systems Protection Board. (b) Consideration of other candidates... eligible ratings for professional and scientific positions at the GS-9 level and above, or equivalent, in... of the following orders: (i) By preference status. Under this method, preference eligibles having a...

  20. Statistical considerations in NRDA studies

    International Nuclear Information System (INIS)

    Harner, E.G.; Parker, K.R.; Skalski, J.R.

    1993-01-01

    Biological, chemical, and toxicological variables are usually modeled with lognormal, Poisson, negative binomial, or binomial error distributions. Species counts and densities often have frequent zeros and overdispersion. Chemical concentrations can have frequent non-detects and a small proportion of high values. The feasibility of making adjustments to these response variables, such as zero-inflated models, are discussed. Toxicity measurements are usually modeled with the binomial distribution. A strategy for determining the most appropriate distribution is presented. Model-based methods, using concomitant variables and interactions, enhance assessment of impacts. Concomitant variable models reduce variability and also reduce bias by adjusting means to a common basis. Variable selection strategies are given for determining the most appropriate set of concomitant variables. Multi-year generalized linear models test impact-by-time interactions, possibly after adjusting for time-dependent concomitant variables. Communities are analyzed to make inferences about overall biological impact and recovery and require non-normal multivariate techniques. Partial canonical corresponding analysis is an appropriate community model for ordinating spatial and temporal shifts due to impact. The Exxon Valdez is used as a case study

  1. Hidden inventory and safety considerations

    International Nuclear Information System (INIS)

    Anderson, A.R.; James, R.H.; Morgan, F.

    1976-01-01

    Preliminary results are described of the evaluation of residual plutonium in a process line used for the production of experimental fast reactor fuel. Initial attention has been focussed on a selection of work boxes used for processing powders and solutions. Amounts of material measured as ''hidden inventory'' are generally less than 0.1 percent of throughput but in one box containing very complex equipment the amount was exceptionally about 0.5 percent. The total surface area of the box and the installed equipment appears to be the most significant factor in determining the amount of plutonium held-up as ''hidden inventory,'' representing an average of about 4 x 10 -4 g cm -2 . Present results are based on gamma spectrometer measurements but neutron techniques are being developed to overcome some of the inherent uncertainties in the gamma method. It is suggested that the routine use of sample plates of known surface area would be valuable in monitoring the deposition of plutonium in work boxes

  2. General Considerations on fiscal evasion

    Directory of Open Access Journals (Sweden)

    Pripoaie Silviu

    2009-10-01

    Full Text Available Analysis of performance of any economy involves the measurement and correlation of three basic elements: the rate of economic growth,the rate of inflation and unemployment rate. When the rate of growth (rate of real GDP is high, the production of goods and services is growing andtherefore increasing the number of jobs, decrease unemployment and raise living standards. If the economy is in recession phase, increasing fiscalpressure to ensure the necessary budgetary funds triggers complex economic mechanisms. Rules more strictly is that those who are not able tooperate in the normal economy to slide towards the underground economy, and this not because he wants to tax evasion, but because they simplycannot cope with new regulations. It is widely accepted in economic theory and practice the idea that reliability scale macroeconomic indicators of acountry is affected by size of underground economy and the various tests made so far on this subject, focusing either on the social aspect or theeconomic or moral, or emphasizes the illegal or the edge of legality. This has led to various studies in this area do not provide comparable data orprovide data to the contrary. Worldwide were put in place, however, some calculation methods provided that applied the same country and sameperiod, the results are rarely consistent, sometimes even in fundamentally different.

  3. NASA GIBS Use in Live Planetarium Shows

    Science.gov (United States)

    Emmart, C. B.

    2015-12-01

    The American Museum of Natural History's Hayden Planetarium was rebuilt in year 2000 as an immersive theater for scientific data visualization to show the universe in context to our planet. Specific astrophysical movie productions provide the main daily programming, but interactive control software, developed at AMNH allows immersive presentation within a data aggregation of astronomical catalogs called the Digital Universe 3D Atlas. Since 2006, WMS globe browsing capabilities have been built into a software development collaboration with Sweden's Linkoping University (LiU). The resulting Uniview software, now a product of the company SCISS, is operated by about fifty planetariums around that world with ability to network amongst the sites for global presentations. Public presentation of NASA GIBS has allowed authoritative narratives to be presented within the range of data available in context to other sources such as Science on a Sphere, NASA Earth Observatory and Google Earth KML resources. Specifically, the NOAA supported World Views Network conducted a series of presentations across the US that focused on local ecological issues that could then be expanded in the course of presentation to national and global scales of examination. NASA support of for GIBS resources in an easy access multi scale streaming format like WMS has tremendously enabled particularly facile presentations of global monitoring like never before. Global networking of theaters for distributed presentations broadens out the potential for impact of this medium. Archiving and refinement of these presentations has already begun to inform new types of documentary productions that examine pertinent, global interdependency topics.

  4. Mining by-products show potential

    International Nuclear Information System (INIS)

    Douglas, Grant

    2013-01-01

    Full text: Many mining and industrial processes generate wastewater that contains a variety of contaminants, such as metals and metalloids. These must be removed to ensure the wastewater is suitable for reuse or safe discharge to the environment. However, mining wastewater treatment processes have traditionally been difficult due to the large range of different contaminants present, requiring a number of complex steps. In current processes, the mining industry generally adds lime to the wastewater to purify it. While often effective, the key issue with this method has been the volume of sludge that forms and the subsequent problems with dealing with this sludge - either to extract the contained water, which often requires additional treatment, or to find enough space for long-term disposal. This complex practice could end soon thanks to a new treatment solution that utilises hydrotalcites. Developed by CSIRO, the treatment overcomes the complexities of lime-based methods and offers a simpler and more water smart process. The CSIRO team found that hydrotalcites, which are layered minerals consisting of aluminium- and magnesium- rich layers, can simultaneously remove a variety of contaminants in wastewater in a single step. Scientists noticed that hydrotalcites begin to form when aluminium and magnesium are present at an ideal ratio and under conditions during neutralisation of acidic waters. As hydrotalcites form, the contaminants become trapped and are easily removed from the wastewater as a solid. Mining wastewater often contains substantial magnesium and aluminium concentrations. This means that we can create hydrotalcites utilising common contaminants that are already present in the wastewater, by simply adjusting their concentrations and adding alkaline compounds to rapidly increase pH. Initial applications have focussed on treating wastewater generated from the mining and extraction of uranium. A range of contaminants including uranium, rare earth elements

  5. Basic consideration of diffusion/perfusion imaging

    International Nuclear Information System (INIS)

    Tamagawa, Yoichi; Kimura, Hirohiko; Matsuda, Tsuyoshi; Kawamura, Yasutaka; Nakatsugawa, Shigekazu; Ishii, Yasushi; Sakuma, Hajime; Tsukamoto, Tetsuji.

    1990-01-01

    In magnetic resonance imaging (MRI), microscopic motion of biological system such as molecular diffusion of water and microcirculation of blood in the capillary network (perfusion) has been proposed to cause signal attenuation as an intravoxel incoherent motion (IVIM). Quantitative imaging of the IVIM phenomenon was attempted to generate from a set of spin-echo (SE) sequences with or without sensitization by motion probing gradient (MPG). The IVIM imaging is characterized by a parameter, apparent diffusion coefficient (ADC), which is an integration of both the diffusion and the perfusion factor on voxel-by-voxel basis. Hard ware was adjusted to avoid image artifact mainly produced by eddy current. Feasibility of the method was tested using bottle phantom filled with water at different temperature and acetone, and the calculated ADC values of these media corresponded well with accepted values of diffusion. The method was then applied to biological system to investigate mutual participation of diffusion/perfusion on the ADC value. The result of tumor model born on nude mouse suggested considerable participation of perfusion factor which immediately disappeared after sacrificing the animal. Meanwhile, lower value of sacrificed tissue without microcirculation was suggested to have some restriction of diffusion factor by biological tissue. To substantiate the restriction effect on the diffusion, a series of observation have made on a fiber phantom, stalk of celory with botanical fibers and human brain with nerve fibers, in applying unidirectional MPG along the course of these banch of fiber system. The directional restriction effect of diffusion along the course of fiber (diffusion anisotrophy) was clearly visualized as directional change of ADC value. The present method for tissue characterization by diffusion/perfusion on microscopic level will provide a new insight for evaluation of functional derangement in human brain and other organs. (author)

  6. Considerations about Cloud Services: Learning

    Directory of Open Access Journals (Sweden)

    Riccardo Cognini

    2013-05-01

    Full Text Available Cloud services are ubiquitous: for small to large companies the phenomenon of cloud service is nowadays a standard business practice. This paper would compile an analysis over a possible implementation of a cloud system, treating especially the legal aspect of this theme. In the Italian market has a large number of issues arise form cloud computing. First of all, this paper investigates the legal issues associated to cloud computing, specific contractual scheme that is able to define rights a duties both of user (private and/or public body and cloud provider. On one side there is all the EU legislative production related to privacy over electronic communication and, furthermore, the Privacy Directive is under a revision process to be more adaptable to new challenges of decentralized data treatment, but concretely there are no any structured and well defined legal instruments. Objectives: we present a possible solution to address the uncertainty of this area, starting from the EU legislative production with the help of the specific Italian scenario that could offer an operative solution. Indeed the Italian legal system is particularly adaptable to changing technologies and it could use as better as possible to adapt the already existing legal tools to this new technological era. Prior work: after an introduction to the state of the art, we show the main issues and their critical points that must be solved. Approach: observation of the state of the art to propose a new approach to find the suitable disciple

  7. Spectrum analysis on quality requirements consideration in software design documents.

    Science.gov (United States)

    Kaiya, Haruhiko; Umemura, Masahiro; Ogata, Shinpei; Kaijiri, Kenji

    2013-12-01

    Software quality requirements defined in the requirements analysis stage should be implemented in the final products, such as source codes and system deployment. To guarantee this meta-requirement, quality requirements should be considered in the intermediate stages, such as the design stage or the architectural definition stage. We propose a novel method for checking whether quality requirements are considered in the design stage. In this method, a technique called "spectrum analysis for quality requirements" is applied not only to requirements specifications but also to design documents. The technique enables us to derive the spectrum of a document, and quality requirements considerations in the document are numerically represented in the spectrum. We can thus objectively identify whether the considerations of quality requirements in a requirements document are adapted to its design document. To validate the method, we applied it to commercial software systems with the help of a supporting tool, and we confirmed that the method worked well.

  8. Geoscience is Important? Show Me Why

    Science.gov (United States)

    Boland, M. A.

    2017-12-01

    "The public" is not homogenous and no single message or form of messaging will connect the entire public with the geosciences. One approach to promoting trust in, and engagement with, the geosciences is to identify specific sectors of the public and then develop interactions and communication products that are immediately relevant to that sector's interests. If the content and delivery are appropriate, this approach empowers people to connect with the geosciences on their own terms and to understand the relevance of the geosciences to their own situation. Federal policy makers are a distinct and influential subgroup of the general public. In preparation for the 2016 presidential election, the American Geosciences Institute (AGI) in collaboration with its 51 member societies prepared Geoscience for America's Critical Needs: Invitation to a National Dialogue, a document that identified major geoscience policy issues that should be addressed in a national policy platform. Following the election, AGI worked with eight other geoscience societies to develop Geoscience Policy Recommendations for the New Administration and the 115th Congress, which outlines specific policy actions to address national issues. State and local decision makers are another important subgroup of the public. AGI has developed online content, factsheets, and case studies with different levels of technical complexity so people can explore societally-relevant geoscience topics at their level of technical proficiency. A related webinar series is attracting a growing worldwide audience from many employment sectors. Partnering with government agencies and other scientific and professional societies has increased the visibility and credibility of these information products with our target audience. Surveys and other feedback show that these products are raising awareness of the geosciences and helping to build reciprocal relationships between geoscientists and decision makers. The core message of all

  9. Bacteriophages show promise as antimicrobial agents.

    Science.gov (United States)

    Alisky, J; Iczkowski, K; Rapoport, A; Troitsky, N

    1998-01-01

    The emergence of antibiotic-resistant bacteria has prompted interest in alternatives to conventional drugs. One possible option is to use bacteriophages (phage) as antimicrobial agents. We have conducted a literature review of all Medline citations from 1966-1996 that dealt with the therapeutic use of phage. There were 27 papers from Poland, the Soviet Union, Britain and the U.S.A. The Polish and Soviets administered phage orally, topically or systemically to treat a wide variety of antibiotic-resistant pathogens in both adults and children. Infections included suppurative wound infections, gastroenteritis, sepsis, osteomyelitis, dermatitis, empyemas and pneumonia; pathogens included Staphylococcus, Streptococcus, Klebsiella, Escherichia, Proteus, Pseudomonas, Shigella and Salmonella spp. Overall, the Polish and Soviets reported success rates of 80-95% for phage therapy, with rare, reversible gastrointestinal or allergic side effects. However, efficacy of phage was determined almost exclusively by qualitative clinical assessment of patients, and details of dosages and clinical criteria were very sketchy. There were also six British reports describing controlled trials of phage in animal models (mice, guinea pigs and livestock), measuring survival rates and other objective criteria. All of the British studies raised phage against specific pathogens then used to create experimental infections. Demonstrable efficacy against Escherichia, Acinetobacter, Pseudomonas and Staphylococcus spp. was noted in these model systems. Two U.S. papers dealt with improving the bioavailability of phage. Phage is sequestered in the spleen and removed from circulation. This can be overcome by serial passage of phage through mice to isolate mutants that resist sequestration. In conclusion, bacteriophages may show promise for treating antibiotic resistant pathogens. To facilitate further progress, directions for future research are discussed and a directory of authors from the reviewed

  10. Social marketing: issues for consideration.

    Science.gov (United States)

    Novelli, W D

    1983-01-01

    Few social organizations have been able to incorporate all the essential components of successful marketing, namely, a customer oriented perspective, careful product development, segmented targets and programs, and an interative process of analysis, planning, implementation, and replanning. The lack of resources is part of the problem of moving forward into comprehensive social marketing. Social organizations may use marketing's 4 "Ps" -- product, price, promotion, and place, but often they must also contend with low visibility, lamentable budgets, little research, and lack of continuity. Several general problems confront marketing planners who try to transfer marketing approaches used to sell toothpaste and laundry detergent to promote concepts like family planning, smoking cessation, and nutrition. It has not been possible simply to apply commercial techniques for market analysis and segmentation or product, price, channel, and communication strategy and implementation to social programs. Evaluating program effectiveness is another area where commercial methods fail to readily apply. Contraceptive social marketing programs can point to quantifiable success measures of units sold and revenue received, but generally social marketers must gauge their longterm program objectives such as reduced fertility rates according to intermediary measures such as knowledge change or reported behavior. Currently, organizational design is being studied by several contraceptive social marketing programs. Trained marketing managers in key positions, a systematic marketing planning process, and careful monitoring and control are key program success ingredients that frequently are missing in social agencies where marketing activities and functions may not be fully understood. Many social organizations have established communication functions, but they are not conducive to the broader role that marketing must play if any significant impact is to result. Additionally, in the absence of

  11. Lunar Module Electrical Power System Design Considerations and Failure Modes

    Science.gov (United States)

    Interbartolo, Michael

    2009-01-01

    This slide presentation reviews the design and redesign considerations of the Apollo lunar module electrical power system. Included in the work are graphics showing the lunar module power system. It describes the in-flight failures, and the lessons learned from these failures.

  12. Cost-benefit considerations in regulatory decision-making

    International Nuclear Information System (INIS)

    Harvie, J.D.

    1996-01-01

    The Atomic Energy Control Board is investigating the feasibility of developing methods for factoring cost-benefit considerations into its regulatory decision-making. This initiative results, in part, from the federal government policy requiring cost-benefit considerations to be taken into account in regulatory processes, and from the recommendations of an Advisory Panel on Regulatory Review in 1993, submitted to the Minister of Natural Resources Canada. One of these recommendations stated: 'that mechanisms be developed to examine cost-benefit issues and work towards some consensus of opinion among stakeholders; a task force on the subject could be an appropriate starting point'. (author)

  13. 32 CFR 643.104 - Consideration.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 4 2010-07-01 2010-07-01 true Consideration. 643.104 Section 643.104 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) REAL PROPERTY REAL ESTATE Permits § 643.104 Consideration. (a) Permits are usually granted on a rent-free basis. (b) The Army is...

  14. 29 CFR 1614.305 - Consideration procedures.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 4 2010-07-01 2010-07-01 false Consideration procedures. 1614.305 Section 1614.305 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION FEDERAL SECTOR EQUAL EMPLOYMENT OPPORTUNITY Related Processes § 1614.305 Consideration procedures. (a) Once a petition is filed...

  15. 48 CFR 226.7104 - Other considerations.

    Science.gov (United States)

    2010-10-01

    ... Businesses 226.7104 Other considerations. When planning for contracts for services related to base closure activities at a military installation affected by a closure or realignment under a base closure law... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Other considerations. 226...

  16. Insurance considerations associated with radiation processing

    International Nuclear Information System (INIS)

    Boylan, F.X.

    1979-01-01

    Comments are made on nuclear insurance experience in the United States. The subject is discussed in more detail under the headings: direct physical damage insurance; workers' compensation insurance; third party liability (premises and operations considerations; products considerations); possible alternatives to the existing arrangement. (U.K.)

  17. 7 CFR 1735.92 - Accounting considerations.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 11 2010-01-01 2010-01-01 false Accounting considerations. 1735.92 Section 1735.92... All Acquisitions and Mergers § 1735.92 Accounting considerations. (a) Proper accounting shall be... in the absence of such a commission, as required by RUS based on Generally Accepted Accounting...

  18. ACCOUNTING FOR CONTINGENT CONSIDERATIONS IN BUSINESS COMBINATIONS

    Directory of Open Access Journals (Sweden)

    Gurgen KALASHYAN

    2017-07-01

    Full Text Available According to IFRS 3 Business Combinations contingent considerations must be included in the total consideration given for the acquired entity along with cash, other assets, ordinary or preference equity instruments, options, warrants. The contingent consideration is the determined amount which acquiring entity has to pay to acquired entity provided, that certain conditions will be fulfilled in the future. In case the provisions are not satisfied, we will get the situation when the amount of contingent consideration has been included in the total consideration given in the business combination, but in fact, the acquirer has not paid that amount. In its turn, the acquired entity will recognize the contingent consideration as a financial asset according to IFRS 9 Financial Instruments. In that case, it would be appropriately to recognize the contingent consideration as a contingent asset applying IAS 37. In the Article the author will explore the challenges of contingent consideration accounting and suggest the ways of solving the above mentioned problems.

  19. DAST in Flight Showing Diverging Wingtip Oscillations

    Science.gov (United States)

    1980-01-01

    Two BQM-34 Firebee II drones were modified with supercritical airfoils, called the Aeroelastic Research Wing (ARW), for the Drones for Aerodynamic and Structural Testing (DAST) program, which ran from 1977 to 1983. In this view of DAST-1 (Serial # 72-1557), taken on June 12, 1980, severe wingtip flutter is visible. Moments later, the right wing failed catastrophically and the vehicle crashed near Cuddeback Dry Lake. Before the drone was lost, it had made two captive and two free flights. Its first free flight, on October 2, 1979, was cut short by an uplink receiver failure. The drone was caught in midair by an HH-3 helicopter. The second free flight, on March 12, 1980, was successful, ending in a midair recovery. The third free flight, made on June 12, was to expand the flutter envelope. All of these missions launched from the NASA B-52. From 1977 to 1983, the Dryden Flight Research Center, Edwards, California, (under two different names) conducted the DAST Program as a high-risk flight experiment using a ground-controlled, pilotless aircraft. Described by NASA engineers as a 'wind tunnel in the sky,' the DAST was a specially modified Teledyne-Ryan BQM-34E/F Firebee II supersonic target drone that was flown to validate theoretical predictions under actual flight conditions in a joint project with the Langley Research Center, Hampton, Virginia. The DAST Program merged advances in electronic remote control systems with advances in airplane design. Drones (remotely controlled, missile-like vehicles initially developed to serve as gunnery targets) had been deployed successfully during the Vietnamese conflict as reconnaissance aircraft. After the war, the energy crisis of the 1970s led NASA to seek new ways to cut fuel use and improve airplane efficiency. The DAST Program's drones provided an economical, fuel-conscious method for conducting in-flight experiments from a remote ground site. DAST explored the technology required to build wing structures with less than

  20. Aquarius study - engineering and economic considerations

    International Nuclear Information System (INIS)

    Griffin, Roger F.

    1970-01-01

    The two previous papers described the scope of the Aquarius Study and the various applications considered in evaluating the use of nuclear explosives for the development of water resources in Arizona. Surface storage behind a dam created with the use of nuclear explosives was selected for the major effort, primarily because it could afford the most valid direct comparison between nuclear and conventional methods. In this paper I will focus on the engineering and economic considerations involved in developing and evaluating three concepts for constructing a rockfill dam using nuclear explosives. Engineering development and economic evaluation of the concepts was the principal responsibility of Bechtel Corporation as a consultant in the study to the Arizona Atomic Energy Commission. We depended heavily on information supplied by the Federal participants, notably the U.S. Bureau of Reclamation for site data and the U.S. AEC*s Lawrence Radiation Laboratory for information on nuclear explosives effects. Since the study report has not yet been published and additional material is still forthcoming, some of the information I will present, such as the cost estimates, may be subject to change and should be considered preliminary. (author)

  1. Discrete modeling considerations in multiphase fluid dynamics

    International Nuclear Information System (INIS)

    Ransom, V.H.; Ramshaw, J.D.

    1988-01-01

    The modeling of multiphase flows play a fundamental role in light water reactor safety. The main ingredients in our discrete modeling Weltanschauung are the following considerations: (1) Any physical model must be cast into discrete form for a digital computer. (2) The usual approach of formulating models in differential form and then discretizing them is potentially hazardous. It may be preferable to formulate the model in discrete terms from the outset. (3) Computer time and storage constraints limit the resolution that can be employed in practical calculations. These limits effectively define the physical phenomena, length scales, and time scales which cannot be directly represented in the calculation and therefore must be modeled. This information should be injected into the model formulation process at an early stage. (4) Practical resolution limits are generally so coarse that traditional convergence and truncation-error analyses become irrelevant. (5) A discrete model constitutes a reduced description of a physical system, from which fine-scale details are eliminated. This elimination creates a statistical closure problem. Methods from statistical physics may therefore be useful in the formulation of discrete models. In the present paper we elaborate on these themes and illustrate them with simple examples. 48 refs

  2. Energy considerations in real estate appraising

    Energy Technology Data Exchange (ETDEWEB)

    None

    1980-04-01

    Purposes of the seminar on the subject, the basis of this report, include the following: (1) to provide the appraiser an opportunity to learn how to identify and analyze the actual physical consumption of energy as well as the energy-saving improvements in properties under appraisal and in comparable sale and lease properties; (2) to help the appraiser in developing methods to keep meaningful records on the energy consumption of subject and comparable properties so as to observe in an orderly way the behavior of buyers, sellers, tenants, landlords, borrowers, and lenders with respect to energy efficiency; and (3) to assist the appraiser in learning to measure the relative sensitivities of the various segments of the market to energy considerations as indicated by differences in sale prices and rentals. To achieve these goals, the seminar employed two case studies, one for a angle-family residence and one for a multi-family building, both in Topeka, Kansas. The case studies are for illustrative purposes only; in applying the lessons of the seminar to their own daily work, students should be careful to develop information that is pertinent to their subject properties and subject areas and not rely on any of the particulars laid out in the cases.

  3. Aquarius study - engineering and economic considerations

    Energy Technology Data Exchange (ETDEWEB)

    Griffin, Roger F [Bechtel Corporation (United States)

    1970-05-15

    The two previous papers described the scope of the Aquarius Study and the various applications considered in evaluating the use of nuclear explosives for the development of water resources in Arizona. Surface storage behind a dam created with the use of nuclear explosives was selected for the major effort, primarily because it could afford the most valid direct comparison between nuclear and conventional methods. In this paper I will focus on the engineering and economic considerations involved in developing and evaluating three concepts for constructing a rockfill dam using nuclear explosives. Engineering development and economic evaluation of the concepts was the principal responsibility of Bechtel Corporation as a consultant in the study to the Arizona Atomic Energy Commission. We depended heavily on information supplied by the Federal participants, notably the U.S. Bureau of Reclamation for site data and the U.S. AEC*s Lawrence Radiation Laboratory for information on nuclear explosives effects. Since the study report has not yet been published and additional material is still forthcoming, some of the information I will present, such as the cost estimates, may be subject to change and should be considered preliminary. (author)

  4. Essential methodological considerations when using grounded theory.

    Science.gov (United States)

    Achora, Susan; Matua, Gerald Amandu

    2016-07-01

    To suggest important methodological considerations when using grounded theory. A research method widely used in nursing research is grounded theory, at the centre of which is theory construction. However, researchers still struggle with some of its methodological issues. Although grounded theory is widely used to study and explain issues in nursing practice, many researchers are still failing to adhere to its rigorous standards. Researchers should articulate the focus of their investigations - the substantive area of interest as well as the focal population. This should be followed by a succinct explanation of the strategies used to collect and analyse data, supported by clear coding processes. Finally, the resolution of the core issues, including the core category and related categories, should be explained to advance readers' understanding. Researchers should endeavour to understand the tenets of grounded theory. This enables 'neophytes' in particular to make methodological decisions that will improve their studies' rigour and fit with grounded theory. This paper complements the current dialogue on improving the understanding of grounded theory methodology in nursing research. The paper also suggests important procedural decisions researchers need to make to preserve their studies' scientific merit and fit with grounded theory.

  5. Large population center and core melt accident considerations in siting

    International Nuclear Information System (INIS)

    Camarinopoulos, L.; Yadigaroglu, G.

    1983-01-01

    The problem of providing suitable demographic siting criteria in the presence of a very large population center in an otherwise sparsely populated region is addressed. Simple calculations were performed making maximum use of pretabulated results of studies where core melt accidents are considered. These show that taking into consideration the air flow patterns in the region can lower the expected population doses from core melt accidents more effectively than distance alone. Expected doses are compared to the annual background radiation dose. A simple siting criterion combining geographical considerations with the probability of a release reaching the large population center is proposed

  6. Towards a comprehensive system of methodological considerations for cities' climate targets

    International Nuclear Information System (INIS)

    Kramers, Anna; Wangel, Josefin; Johansson, Stefan; Höjer, Mattias; Finnveden, Göran; Brandt, Nils

    2013-01-01

    Climate targets for cities abound. However, what these targets really imply is dependent on a number of decisions regarding system boundaries and methods of calculation. In order to understand and compare cities' climate targets, there is a need for a generic and comprehensive framework of key methodological considerations. This paper identifies eight key methodological considerations for the different choices that can be made when setting targets for GHG emissions in a city and arranges them in four categories: temporal scope of target, object for target setting, unit of target, and range of target. To explore how target setting is carried out in practice, the climate targets of eight European cities were analysed. The results showed that these targets cover only a limited part of what could be included. Moreover, the cities showed quite limited awareness of what is, or could be, include in the targets. This makes comparison and benchmarking between cities difficult. - Highlights: • Cities' climate targets are almost impossible to compare and benchmark. • There is a need for consistent protocols and frameworks supporting target setting. • A framework with key methodological considerations for cities' climate targets is identified. • The framework is used to explore the climate targets for eight European cities. • The difference between production- and consumption based accounting is illustrated in a new way

  7. Consideration of the official recognition of victims of environmental pollution. I. Environmental pollution in Toroku

    Energy Technology Data Exchange (ETDEWEB)

    Ota, T; Goto, M; Ryuraku, Y; Une, H; Ogawa, T; Goda, S

    1975-04-01

    The Toroku area in Miyazaki Prefecture has been appointed for special consideration of air-pollution related health disturbance victims and 48 inhabitants were selected for repeated medical examinations since 1971. The morbidities of subjective symptoms between a recognized group air pollution victims and an unrecognized group showed almost no difference. According to medical examinations, symptoms such as swelling of liver, decrease of sensation in the upper extremities, and decrease of sense of pain were very prevalent in both groups. Health problems in this area are due to arsenic, other elements, and sulfur dioxide; therefore, the presently used screening method for symptoms only due to arsenic is not appropriate.

  8. Legal considerations for urban underground space development in Malaysia

    Directory of Open Access Journals (Sweden)

    F. Zaini

    2017-12-01

    Full Text Available In 2008, the Malaysia land code, named the National Land Code 1965 (NLC 1965, was amended to add Part Five (A to deal with the disposal of underground space. In addition, the Circular of the Director General of Lands and Mines No. 1/2008 was issued to assist the application of Part Five (A of the NLC 1965. However, the legislation is still questionable and has instigated many arguments among numerous actors. Therefore, this research was undertaken to examine legal considerations for the development of underground space. The focus is on four legal considerations, namely underground space ownership, the bundle of rights, depth, and underground space utilization. Rooted in qualitative methods, interviews were conducted with respondents involved in the development of underground space in Malaysia. The obtained data were then analyzed descriptively. The findings differentiated the rights of landowners for surface land and underground space, and their liability for damages and the depth. It was indicated that the current legislation in Malaysia, namely Part Five (A of the NLC 1965 and the Circular of the Director General of Lands and Mines No. 1/2008, is adequate to facilitate the development of underground space in terms of legal considerations. However, to further facilitate the development of underground land in the future, based on the research, four enhancements are recommended for legal considerations pertaining to the development of underground space in Malaysia. Keywords: Underground space, Legal consideration, Land right, Urban development

  9. Procrastination, consideration of future consequences, and episodic future thinking.

    Science.gov (United States)

    Rebetez, Marie My Lien; Barsics, Catherine; Rochat, Lucien; D'Argembeau, Arnaud; Van der Linden, Martial

    2016-05-01

    Despite the intrinsic temporal nature of procrastination, little research has examined the link between this form of self-regulatory failure and the consideration of future consequences, and no study has addressed the link between procrastination and episodic future thinking. The aim of the present study was to explore these relationships. Participants were asked to project themselves into possible future events and to rate the amount of sensory-perceptual details and autonoetic consciousness associated with their representations. They were also asked to complete questionnaires that assessed procrastination, the consideration of future consequences, and negative affect. Results showed that both the consideration of future consequences and episodic future thinking were associated with procrastination, and in particular with procrastination-related decision making abilities and procrastination-related motivational dispositions, respectively. Copyright © 2016 Elsevier Inc. All rights reserved.

  10. Time dependent patient no-show predictive modelling development.

    Science.gov (United States)

    Huang, Yu-Li; Hanauer, David A

    2016-05-09

    Purpose - The purpose of this paper is to develop evident-based predictive no-show models considering patients' each past appointment status, a time-dependent component, as an independent predictor to improve predictability. Design/methodology/approach - A ten-year retrospective data set was extracted from a pediatric clinic. It consisted of 7,291 distinct patients who had at least two visits along with their appointment characteristics, patient demographics, and insurance information. Logistic regression was adopted to develop no-show models using two-thirds of the data for training and the remaining data for validation. The no-show threshold was then determined based on minimizing the misclassification of show/no-show assignments. There were a total of 26 predictive model developed based on the number of available past appointments. Simulation was employed to test the effective of each model on costs of patient wait time, physician idle time, and overtime. Findings - The results demonstrated the misclassification rate and the area under the curve of the receiver operating characteristic gradually improved as more appointment history was included until around the 20th predictive model. The overbooking method with no-show predictive models suggested incorporating up to the 16th model and outperformed other overbooking methods by as much as 9.4 per cent in the cost per patient while allowing two additional patients in a clinic day. Research limitations/implications - The challenge now is to actually implement the no-show predictive model systematically to further demonstrate its robustness and simplicity in various scheduling systems. Originality/value - This paper provides examples of how to build the no-show predictive models with time-dependent components to improve the overbooking policy. Accurately identifying scheduled patients' show/no-show status allows clinics to proactively schedule patients to reduce the negative impact of patient no-shows.

  11. Euthanasia of Cattle: Practical Considerations and Application

    Science.gov (United States)

    Shearer, Jan Keith

    2018-01-01

    type of bullet are important considerations when gunshot is used. When captive bolt is used, a penetrating captive bolt loaded with the appropriate powder charge and accompanied by a follow up (adjunctive) step to assure death are required. The success of physical methods also requires careful selection of the anatomic site for entry of a “free bullet” or “bolt” in the case of penetrating captive bolt. Disease eradication plans for animal health emergencies necessitate methods of euthanasia that will facilitate rapid and efficient depopulation of animals while preserving their welfare to the greatest extent possible. A portable pneumatic captive bolt device has been developed and validated as effective for use in mass depopulation scenarios. Finally, while most tend to focus on the technical aspects of euthanasia, it is extremely important that no one forget the human cost for those who may be required to perform the task of euthanasia on a regular basis. Symptoms including depression, grief, sleeplessness and destructive behaviors including alcoholism and drug abuse are not uncommon for those who participate in the euthanasia of animals. PMID:29673140

  12. The relationship between trait self-control, consideration for future consequence and organizational citizenship behavior among Chinese employees.

    Science.gov (United States)

    Wang, Yu-Jie; Dou, Kai; Tang, Zhi-Wen

    2017-01-01

    Organizational citizenship behavior (OCB) is important to the development of an organization. Research into factors that foster OCB and the underlying processes are therefore substantially crucial. The current study aimed to test the association between trait self-control and OCB and the mediating role of consideration for future consequence. Four hundred and ninety-four Chinese employees (275 men, 219 women) took part in the study. Participants completed a battery of self-report measures online that assessed trait self-control, tendencies of consideration of future consequence, and organizational citizenship behavior. Path analysis was conducted and bootstrapping technique (N = 5000), a resampling method that is asymptotically more accurate than the standard intervals using sample variance and assumptions of normality, was used to judge the significance of the mediation. Results of path analysis showed that trait self-control was positively related to OCB. More importantly, the "trait self-control-OCB" link was mediated by consideration of future consequence-future, but not by consideration of future consequence-immediate. Employees with high trait self-control engage in more organizational citizenship behavior and this link can be partly explained by consideration of future consequence-future.

  13. Creating Library Interiors: Planning and Design Considerations.

    Science.gov (United States)

    Jones, Plummer Alston, Jr.; Barton, Phillip K.

    1997-01-01

    Examines design considerations for public library interiors: access; acoustical treatment; assignable and nonassignable space; building interiors: ceilings, clocks, color, control, drinking fountains; exhibit space: slotwall display, floor coverings, floor loading, furniture, lighting, mechanical systems, public address, copying machines,…

  14. Safety considerations for compressed hydrogen storage systems

    International Nuclear Information System (INIS)

    Gleason, D.

    2006-01-01

    An overview of the safety considerations for various hydrogen storage options, including stationary, vehicle storage, and mobile refueling technologies. Indications of some of the challenges facing the industry as the demand for hydrogen fuel storage systems increases. (author)

  15. [Theological moral considerations of advance directives].

    Science.gov (United States)

    Virt, G

    1997-01-01

    The forms for advanced directives vary considerably in respect to content and wording. This article intends to develop ethical criteria for such texts, from the moraltheological point of view, also considering the social context.

  16. 32 CFR 643.83 - Consideration.

    Science.gov (United States)

    2010-07-01

    ... consideration in an amount equal to the fair market value as established by recognized appraisal practices. As... thereof, will not require fair market value when the purpose of the easement is to serve the public...

  17. Thermal-hydraulic calculation methods for transients and accidents of the reactor cooling system under special consideration of multi-dimensional flows (ATHLET, FLUBOX, CFX). Final report; Thermohydraulische Rechenmethoden zu Transienten und Stoerfaellen im Reaktorkuehlkreislauf unter besonderer Beruecksichtigung mehrdimensionaler Stroemungen (ATHLET, FLUBOX, CFX). Abschlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    Glaeser, H.; Graf, U.; Herb, J.; and others

    2012-02-15

    The project RS1184 „Thermal-hydraulic Calculation Methods for Transients and Accidents of the Reactor Cooling System Under Special Consideration of Multi-Dimensional Flows (ATHLET, FLUBOX, CFX)'' consists of four work packages: 1. Further development of the computer code ATHLET 2. Termination of FLUBOX development and development of an ATHLET-internal 3D module 3. Coupling of ATHLET and CFD code ANSYS CFX as well as CFX model development to simulate three-dimensional flows in the reactor coolant system 4. Prediction capability of computer code ATHLET. One of the superior objectives of the project is to improve the prediction capability of the thermal-hydraulic system code ATHLET, including the simulation of multi-dimensional flow in the reactor vessel. The constitutive equations in ATHLET, especially the momentum equations in ATHLET, are written in one-dimensional form. It was planned to develop the 2D/3D module FLUBOX further and couple it with ATHLET. Due to reasons given in chapter 3, the FLUBOX development was terminated. Instead, the decision was made to develop a fast running internal ATHLET-module. The 2D/3D equations for ATHLET have been derived and were implemented. That strategy allows using all ATHLET models and the ATHLET code structure. An additional advantage is that different numerical schemes of different codes, and consequently a loss of efficiency, will be avoided. A second possibility is the coupling of ATHLET with the CFD code ANSYS CFX. Such a coupled code system will be used in those cases when a part of the simulation area is needed to be calculated with high resolution. Such a detailed modelling cannot be provided by ATHLET-3D. A complete representation of the cooling system by a CFD code cannot be performed due to calculation time. In order to calculate the complete system behavior still with ATHLET, that part to be investigated in more detail, will be replaced by a CFX model. Several new models and improvements of existing

  18. The Importance of Muscular Strength: Training Considerations.

    Science.gov (United States)

    Suchomel, Timothy J; Nimphius, Sophia; Bellon, Christopher R; Stone, Michael H

    2018-04-01

    This review covers underlying physiological characteristics and training considerations that may affect muscular strength including improving maximal force expression and time-limited force expression. Strength is underpinned by a combination of morphological and neural factors including muscle cross-sectional area and architecture, musculotendinous stiffness, motor unit recruitment, rate coding, motor unit synchronization, and neuromuscular inhibition. Although single- and multi-targeted block periodization models may produce the greatest strength-power benefits, concepts within each model must be considered within the limitations of the sport, athletes, and schedules. Bilateral training, eccentric training and accentuated eccentric loading, and variable resistance training may produce the greatest comprehensive strength adaptations. Bodyweight exercise, isolation exercises, plyometric exercise, unilateral exercise, and kettlebell training may be limited in their potential to improve maximal strength but are still relevant to strength development by challenging time-limited force expression and differentially challenging motor demands. Training to failure may not be necessary to improve maximum muscular strength and is likely not necessary for maximum gains in strength. Indeed, programming that combines heavy and light loads may improve strength and underpin other strength-power characteristics. Multiple sets appear to produce superior training benefits compared to single sets; however, an athlete's training status and the dose-response relationship must be considered. While 2- to 5-min interset rest intervals may produce the greatest strength-power benefits, rest interval length may vary based an athlete's training age, fiber type, and genetics. Weaker athletes should focus on developing strength before emphasizing power-type training. Stronger athletes may begin to emphasize power-type training while maintaining/improving their strength. Future research should

  19. Consideration of margins for hypo fractionated radiotherapy

    International Nuclear Information System (INIS)

    Herschtal, A.; Foroudi, F.; Kron, T.

    2010-01-01

    Full text: Geographical misses of the tumour are of concern in radiotherapy and are typically accommodated by introducing margins around the target. However, there is a trade-off between ensuring the target receives sufficient dose and minimising the dose to surrounding normal structures. Several methods of determining margin width have been developed with the most commonly used one proposed by M. VanHerk (VanHerk UROBP 52: 1407, 2002). VanHerk's model sets margins to achieve 95% of dose coverage for the target in 90% of patients. However, this model was derived assuming an infinite number of fractions. The aim of the present work is to estimate the modifications necessary to the model if a finite number of fractions are given. Software simulations were used to determine the true probability of a patient achieving 95% target coverage if different fraction numbers are used for a given margin width. Model parameters were informed by a large data set recently acquired at our institution using daily image guidance for prostate cancer patients with implanted fiducial markers. Assuming a 3 mm penumbral width it was found that using the VanHerk model only 74 or 54% of patients receive 95% of the prescription dose if 20 or 6 fractions are given, respectively. The steep dose gradients afforded by IMRT are likely to make consideration of the effects of hypofractionation more important. It is necessary to increase the margins around the target to ensure adequate tumour coverage if hypofractionated radiotherapy is to be used for cancer treatment. (author)

  20. Show Horse Welfare: Horse Show Competitors' Understanding, Awareness, and Perceptions of Equine Welfare.

    Science.gov (United States)

    Voigt, Melissa A; Hiney, Kristina; Richardson, Jennifer C; Waite, Karen; Borron, Abigail; Brady, Colleen M

    2016-01-01

    The purpose of this study was to gain a better understanding of stock-type horse show competitors' understanding of welfare and level of concern for stock-type show horses' welfare. Data were collected through an online questionnaire that included questions relating to (a) interest and general understanding of horse welfare, (b) welfare concerns of the horse show industry and specifically the stock-type horse show industry, (c) decision-making influences, and (d) level of empathic characteristics. The majority of respondents indicated they agree or strongly agree that physical metrics should be a factor when assessing horse welfare, while fewer agreed that behavioral and mental metrics should be a factor. Respondent empathy levels were moderate to high and were positively correlated with the belief that mental and behavioral metrics should be a factor in assessing horse welfare. Respondents indicated the inhumane practices that most often occur at stock-type shows include excessive jerking on reins, excessive spurring, and induced excessive unnatural movement. Additionally, respondents indicated association rules, hired trainers, and hired riding instructors are the most influential regarding the decisions they make related to their horses' care and treatment.

  1. Considerations in using radiation dosimetry data in epidemiologic studies

    International Nuclear Information System (INIS)

    Hudson, D.H.; Beck, W.L.; Fry, S.A.; Lushbaugh, C.C.; Watson, J.

    1983-01-01

    From experience to date, it is concluded that cohorts can be divided into useable risk groups without need for extensive calculations of individual doses. Several possible risk group classification schemes are presented for use with standard methods of data analysis. The rationale, advantages, and disadvantages of each are discussed with respect to possible classification biases, and statistical and practical considerations. Data from a cohort of nuclear material workers are used to illustrate these dichotomous and ordinal schemes

  2. Discriminating individually considerate and authoritarian leaders by speech activity cues

    OpenAIRE

    Feese, Sebastian; Muaremi, Amir; Arnrich, Bert; Tröster, Gerhard; Meyer, Bertolt; Jonas, Klaus

    2011-01-01

    Effective leadership can increase team performance, however up to now the influence of specific micro-level behavioral patterns on team performance is unclear. At the same time, current behavior observation methods in social psychology mostly rely on manual video annotations that impede research. In our work, we follow a sensor-based approach to automatically extract speech activity cues to discriminate individualized considerate from authoritarian leadership. On a subset of 35 selected...

  3. Innovative Nuclear Power Plant Building Arrangement in Consideration of Decommissioning

    OpenAIRE

    Won-Jun Choi; Myung-Sub Roh; Chang-Lak Kim

    2017-01-01

    A new concept termed the Innovative Nuclear Power Plant Building Arrangement (INBA) strategy is a new nuclear power plant building arrangement method which encompasses upfront consideration of more efficient decommissioning. Although existing decommissioning strategies such as immediate dismantling and differed dismantling has the advantage of either early site restoration or radioactive decommissioning waste reduction, the INBA strategy has the advantages of both strategies. In this research...

  4. Mechatronic Design - Still a Considerable Challenge

    DEFF Research Database (Denmark)

    Torry-Smith, Jonas; Qamar, Ahsan; Achiche, Sofiane

    2011-01-01

    Development of mechatronic products is traditionally carried out by several design experts from different design domains. Performing development of mechatronic products is thus greatly challenging. In order to tackle this, the critical challenges in mechatronics have to be well understood and well...... supported through applicable methods and tools. This paper aims at identifying the major challenges, by conducting a survey of the most relevant research work in mechatronic design. Solutions proposed in literature are assessed and illustrated through a case study in order to investigate, if the challenges...... can be handled appropriately by the methods, tools, and mindsets suggested by the mechatronic community. Using a real world mechatronics case, the paper identifies the areas where further research is required, by showing a clear connection between the actual problems faced during the design task...

  5. Life course models: improving interpretation by consideration of total effects.

    Science.gov (United States)

    Green, Michael J; Popham, Frank

    2017-06-01

    Life course epidemiology has used models of accumulation and critical or sensitive periods to examine the importance of exposure timing in disease aetiology. These models are usually used to describe the direct effects of exposures over the life course. In comparison with consideration of direct effects only, we show how consideration of total effects improves interpretation of these models, giving clearer notions of when it will be most effective to intervene. We show how life course variation in the total effects depends on the magnitude of the direct effects and the stability of the exposure. We discuss interpretation in terms of total, direct and indirect effects and highlight the causal assumptions required for conclusions as to the most effective timing of interventions. © The Author 2016. Published by Oxford University Press on behalf of the International Epidemiological Association.

  6. Consideration of climate change on environmental impact assessment in Spain

    Energy Technology Data Exchange (ETDEWEB)

    Enríquez-de-Salamanca, Álvaro, E-mail: aenriquez@draba.org [Escuela de Doctorado, Universidad Nacional de Educación a Distancia, UNED, Draba Ingeniería y Consultoría Medioambiental, Cañada Nueva, 29, 28200 San Lorenzo de El Escorial (Spain); Martín-Aranda, Rosa M., E-mail: rmartin@ccia.uned.es [Departamento de Química Inorgánica y Química Técnica, Facultad de Ciencias, Universidad Nacional de Educación a Distancia, UNED, Paseo Senda del Rey, 9, 28040, Madrid (Spain); Díaz-Sierra, Rubén, E-mail: sierra@dfmf.uned.es [Departamento de Física Matemática y de Fluidos, Facultad de Ciencias, Universidad Nacional de Educación a Distancia, UNED, Paseo Senda del Rey, 9, 28040, Madrid (Spain)

    2016-02-15

    Most of the projects subject to environmental impact assessment (EIA) are closely related to climate change, as they contribute to or are affected by it. The growing certainty about climate change and its impacts makes its consideration an essential part of the EIA process, as well as in strategic environmental assessment (SEA). This paper examines how climate change (CC) has been taken into account in EIA in Spain through the analysis of 1713 environmental records of decision (RODs) of projects submitted for EIA. In 2013 Spain approved one of the most advanced laws in terms of CC consideration in environmental assessment, although it had not yet accumulated extensive practice on the issue. This contrasts with the situation of countries like Canada or the USA, which have a significant body of experience without specific legal requirements. Only 14% of the RODs analysed included references to CC, and in more than half of the cases it was a mere citation. Thermal power plants, which are subject to specific GHG regulations, show the highest consideration, while transport infrastructures, which are important contributors to CC, show a very low consideration. Almost all the references are related to their contribution to CC, while consideration of the effects of CC is minimal. The increasingly common incorporation of CC into SEA, should not imply its exclusion from EIA, because both processes have different aims and uses. Including the obligation to consider CC in the EIA regulations is highly desirable, but probably not enough without other measures, such as practical guidance, training and motivational programmes for practitioners and evaluators. But even these actions cannot ensure effective and adequate assessments of CC. Probably more resources should be spent on creating greater awareness in all the agents involved in EIA. - Highlights: • We analyse how the climate change is considered in EIA in Spain. • Few projects seriously assess climate change.

  7. Consideration of climate change on environmental impact assessment in Spain

    International Nuclear Information System (INIS)

    Enríquez-de-Salamanca, Álvaro; Martín-Aranda, Rosa M.; Díaz-Sierra, Rubén

    2016-01-01

    Most of the projects subject to environmental impact assessment (EIA) are closely related to climate change, as they contribute to or are affected by it. The growing certainty about climate change and its impacts makes its consideration an essential part of the EIA process, as well as in strategic environmental assessment (SEA). This paper examines how climate change (CC) has been taken into account in EIA in Spain through the analysis of 1713 environmental records of decision (RODs) of projects submitted for EIA. In 2013 Spain approved one of the most advanced laws in terms of CC consideration in environmental assessment, although it had not yet accumulated extensive practice on the issue. This contrasts with the situation of countries like Canada or the USA, which have a significant body of experience without specific legal requirements. Only 14% of the RODs analysed included references to CC, and in more than half of the cases it was a mere citation. Thermal power plants, which are subject to specific GHG regulations, show the highest consideration, while transport infrastructures, which are important contributors to CC, show a very low consideration. Almost all the references are related to their contribution to CC, while consideration of the effects of CC is minimal. The increasingly common incorporation of CC into SEA, should not imply its exclusion from EIA, because both processes have different aims and uses. Including the obligation to consider CC in the EIA regulations is highly desirable, but probably not enough without other measures, such as practical guidance, training and motivational programmes for practitioners and evaluators. But even these actions cannot ensure effective and adequate assessments of CC. Probably more resources should be spent on creating greater awareness in all the agents involved in EIA. - Highlights: • We analyse how the climate change is considered in EIA in Spain. • Few projects seriously assess climate change.

  8. Hydraulic design considerations for a multi-tube sodium economizer

    International Nuclear Information System (INIS)

    Hassberger, J.A.; McConnell, P.M.; Olson, W.H.

    1975-01-01

    Operating experience gained from tests shows that flow distribution effects can severely affect the thermal performance of high effectiveness, low pressure drop sodium heat exchangers. It has been shown that design efforts for such devices must include proper consideration of potential causes of flow maldistribution within the tube bundle. Furthermore, it has been demonstrated that fairly simple design features can be capable of eliminating detrimental flow fields in the tube bundle

  9. Somatic disorders and ergonomic considerations in computer use among the employees of a University

    Directory of Open Access Journals (Sweden)

    Aram Tirgar

    2015-12-01

    Full Text Available Introduction & Purpose: Musculoskeletal disorders (MSDs and computer work are common in majority of the society and both show an increasing trend. This study was conducted to survey on Somatic disorders, MSDs frequency and ergonomic considerations awareness regarding computer use among the employees of Babol University of Medical Sciences (North of Iran. Methods: This cross-sectional study was conducted on 128 administrative staff of medical, dental and paramedical faculties in 2012. The samples were collected by simple method the data were gathered by means of a tailor-made data collection sheet that consisted of 5 open and 13 closed-ended questions. The data were analyzed with descriptive and analytical statistical indexes. Results: According to our data, the mean age of employees was 38.16±7.78 years, 55.5% were females and 63.3% were in bachelor’s degree. More than fifty percent of the samples spend 2 hours or more on their computer a day. Seventy two percent of the staff reported experiencing one or more MSDs symptoms and less than 10% of them were aware of ergonomic considerations in this regard. Chi-square test result showed that a significant statistical difference between MSDs with duration of using computer. (p<0.05 Conclusion: Our results indicated that more than fifty percent of the administrative staff complains of MSDs, most of them were unaware of ergonomics considerations, and many of the employees were eager to learn about the related subject. So, ergonomic interventions and training courses to prevent MSDs are recommended.

  10. Site identification: environmental and radiological considerations

    International Nuclear Information System (INIS)

    Waite, D.A.

    1980-01-01

    Radiological and environmental considerations are recognized as being of utmost importance in planning, siting, licensing, operating, and decommissioning a high-level nuclear waste repository. In such a complex undertaking, it is important to identify the major concerns anticipated to arise in all of these phases in order to address them as early as possible in the program. Three representative activities/studies are summarized which will identify some of the important radiological and environmental considerations which must be addressed through this prolonged sequence of events and will indicate how these considerations are being addressed. It should be emphasized that these are only three of many which could have been chosen. The three key activities/studies are: (1) the NWTS Program criteria for identifying repository sites, (2) the generic guide for preparing environmental evaluations for deep drilling and (3) a preliminary environmental assessment for disposal of mined rock during excavation of a repository

  11. Ethical considerations of therapeutic hypnosis and children.

    Science.gov (United States)

    Etzrodt, Christine M

    2013-04-01

    Historically, therapeutic hypnosis has been met with skepticism within some fields, although acceptance has expanded in recent decades. Development and application of ethical standards and principles has contributed to increased acceptance of hypnosis with children. The Ethics Code of the American Psychological Association (APA, 2002) and the Code of Conduct of the American Society of Clinical Hypnosis (ASCH, 2000) serve as guides to ethical considerations when treating children. From a developmental and practical perspective, children have limited decision-making capacities, therefore special attention should be paid to their rights and welfare. Important ethical considerations relevant to children and hypnosis have emerged, including competence, supervision, informed consent, confidentiality, and boundaries. Considerations are reviewed from a normal and abnormal child development perspective.

  12. Genoa Boat Show – Good Example of Event Management

    Directory of Open Access Journals (Sweden)

    Dunja Demirović

    2012-07-01

    Full Text Available International Boat Show, a business and tourist event, has been held annually in Italian city of Genoa since 1962. The fair is one of the oldest, largest and best known in the field of boating industry worldwide, primarily due to good management of the event and it can serve as case study for domestic fair organizers to improve the quality of their business and services. Since Belgrade is the city of fairs, but compared to Genoa still underdeveloped in terms of trade shows, the following tasks imposed naturally in this study: to determine the relationship of the organizers of Genoa Boat Show in the sector of preparation and fair offer, in the sector of selection and communication with specific target groups (especially visitors, services during the fair and functioning of the city during the fair. During the research the authors have mostly used historical method, comparison, synthesis and the interview method. The results of theoretical research, in addition, may help not only managers of fair shows and of exhibitions, but also to organizers of other events in our country

  13. Low-water considerations for NPP sites

    International Nuclear Information System (INIS)

    Jensen, J.; Frank, T.; Wahl, T.

    2009-01-01

    In the frame of reactor safety considerations flood protection and the evaluation of low-water events are safety relevant issues. Therefore low-water statistics were performed for the coastal region Cuxhaven and the Elbe river estuary. The consideration of the longitudinal profile of water levels during low-tide in connection with surface water effects, morphodynamic changes of the river and anthropogenic modifications is of importance for conclusions concerning the NPP sites in some distance of the reference tide gauge. The authors performed a statistical low-tide analysis for the NPP sites Brunsbuettel and Brokdorf.

  14. Considerations related to Cernavoda NPP lifetime management

    International Nuclear Information System (INIS)

    Cojan, Mihail

    2007-01-01

    Cernavoda NPP, the first CANDU in Europe, is one of the original CANDU 6 plants and the first CANDU 6 producing over 706 MWe. While the first series of CANDU 6 plants (which entered service in the early 1980 s) have now reached the 2/3 of their 30 years design life, the Cernavoda NPP was put into service on the 2nd December 1996. After 10 years of operation the Plant Life Management (PLiM) Program for Cernavoda should be an increasingly important program to Utility ('CNE - Prod') in order to protect the investment and the continued success of plant operation. The goal of the paper is to present some considerations related to Cernavoda NPP lifetime management. The Plant Life Management Program, known as PLiM Program is concerned with the analysis of technical limits of the safe operation - from the point of view of nuclear safety - in NPP units, aiming at attaining the planned 30 years life duration and its extension to 40 or even 50 years of safe and economical operation. For the CANDU reactors the so-called PLiM and PLEX Programs are just applied. These are applied research programs that approach with priority the current practices for assessing the capability of safe operation within the limits of nuclear safety (fitness-for-service assessment). These programs also approach inspection, monitoring are prevention of degrading due to the ageing of critical systems, structures and components (CSSCs). As each nuclear plant is somewhat different in its components and systems, materials composition, procurement, construction, and operational history, directed research and development programs into materials behavior, monitoring techniques, and methods to mitigate ageing are required to support the lifetime management. Over the past 6 years, INR Pitesti (Institute for Nuclear Research - Romania) has been working on R and D Programs to support a comprehensive and integrated Cernavoda NPP Life Management Program (PLiM) that will see the Cernavoda NPP successfully and

  15. Design Considerations for a Flexible Multigrid Preconditioning Library

    Directory of Open Access Journals (Sweden)

    Jérémie Gaidamour

    2012-01-01

    Full Text Available MueLu is a library within the Trilinos software project [An overview of Trilinos, Technical Report SAND2003-2927, Sandia National Laboratories, 2003] and provides a framework for parallel multigrid preconditioning methods for large sparse linear systems. While providing efficient implementations of modern multigrid methods based on smoothed aggregation and energy minimization concepts, MueLu is designed to be customized and extended. This article gives an overview of design considerations for the MueLu package: user interfaces, internal design, data management, usage of modern software constructs, leveraging Trilinos capabilities, linear algebra operations and advanced application.

  16. Tomato Fruits Show Wide Phenomic Diversity but Fruit Developmental Genes Show Low Genomic Diversity.

    Directory of Open Access Journals (Sweden)

    Vijee Mohan

    Full Text Available Domestication of tomato has resulted in large diversity in fruit phenotypes. An intensive phenotyping of 127 tomato accessions from 20 countries revealed extensive morphological diversity in fruit traits. The diversity in fruit traits clustered the accessions into nine classes and identified certain promising lines having desirable traits pertaining to total soluble salts (TSS, carotenoids, ripening index, weight and shape. Factor analysis of the morphometric data from Tomato Analyzer showed that the fruit shape is a complex trait shared by several factors. The 100% variance between round and flat fruit shapes was explained by one discriminant function having a canonical correlation of 0.874 by stepwise discriminant analysis. A set of 10 genes (ACS2, COP1, CYC-B, RIN, MSH2, NAC-NOR, PHOT1, PHYA, PHYB and PSY1 involved in various plant developmental processes were screened for SNP polymorphism by EcoTILLING. The genetic diversity in these genes revealed a total of 36 non-synonymous and 18 synonymous changes leading to the identification of 28 haplotypes. The average frequency of polymorphism across the genes was 0.038/Kb. Significant negative Tajima'D statistic in two of the genes, ACS2 and PHOT1 indicated the presence of rare alleles in low frequency. Our study indicates that while there is low polymorphic diversity in the genes regulating plant development, the population shows wider phenotype diversity. Nonetheless, morphological and genetic diversity of the present collection can be further exploited as potential resources in future.

  17. Dogs do not show pro-social preferences towards humans.

    Directory of Open Access Journals (Sweden)

    Mylène Quervel-Chaumette

    2016-10-01

    Full Text Available Pro-social behaviors are defined as voluntary actions that benefit others. Comparative studies have mostly focused on investigating the presence of pro-sociality across species in an intraspecific context. Taken together, results on both primates and non-primate species indicate that reliance on cooperation may be at work in the selection and maintenance of pro-social sentiments. Dogs appear to be the ideal model when investigating a species’ propensity for pro-sociality in an interspecific context since it has been suggested that as a consequence of domestication, they evolved an underlying temperament encouraging greater propensity to cooperate with human partners. In a recent study, using a food delivery paradigm, dogs were shown to preferentially express pro-social choices towards familiar compared to unfamiliar conspecifics. Using the same set-up and methods in the current study, we investigated dogs’ pro-social preferences towards familiar and unfamiliar human partners. We found that dogs’ pro-social tendencies did not extend to humans and the identity of the human partners did not influence the rate of food delivery. Interestingly, dogs tested with their human partners spent more time gazing at humans, and did so for longer after food consumption had ended than dogs tested with conspecific partners in the initial study. To allow comparability between results from dogs tested with a conspecific and a human partner, the latter were asked not to communicate with dogs in any way. However, this lack of communication from the human may have been aversive to dogs, leading them to cease performing the task earlier compared to the dogs paired with familiar conspecifics in the prior study. This is in line with previous findings suggesting that human communication in such contexts highly affects dogs’ responses. Consequently, we encourage further studies to examine dogs’ pro-social behavior towards humans taking into consideration their

  18. Leaf traits show different relationships with shade tolerance in moist versus dry tropical forests

    NARCIS (Netherlands)

    Poorter, L.

    2009-01-01

    ¿ Shade tolerance is the central paradigm for understanding forest succession and dynamics, but there is considerable debate as to what the salient features of shade tolerance are, whether adult leaves show similar shade adaptations to seedling leaves, and whether the same leaf adaptations are found

  19. Short-term Probabilistic Load Forecasting with the Consideration of Human Body Amenity

    Directory of Open Access Journals (Sweden)

    Ning Lu

    2013-02-01

    Full Text Available Load forecasting is the basis of power system planning and design. It is important for the economic operation and reliability assurance of power system. However, the results of load forecasting given by most existing methods are deterministic. This study aims at probabilistic load forecasting. First, the support vector machine regression is used to acquire the deterministic results of load forecasting with the consideration of human body amenity. Then the probabilistic load forecasting at a certain confidence level is given after the analysis of error distribution law corresponding to certain heat index interval. The final simulation shows that this probabilistic forecasting method is easy to implement and can provide more information than the deterministic forecasting results, and thus is helpful for decision-makers to make reasonable decisions.

  20. Anaesthetic considerations for paediatric laparoscopy | Lasersohn ...

    African Journals Online (AJOL)

    Children, infants and neonates represent an anaesthetic challenge because of age-specific anatomical and physiological issues. Apart from paediatric-specific anaesthetic considerations, the paediatric anaesthetist must understand the implications of laparoscopic surgery, and prevent and react appropriately to changes ...

  1. Writing about Clients: Ethical Considerations and Options

    Science.gov (United States)

    Sperry, Len; Pies, Ronald

    2010-01-01

    Today, the decision to prepare clinical case material for publication is a decision that cannot be taken lightly. The decision involves reviewing ethical considerations and choosing among various options to safeguard client privacy. Such options include seeking the client's permission, disguising case material, and developing composite case…

  2. Implementing Sustainability Considerations in Packaging Design Curricula

    NARCIS (Netherlands)

    Mulder-Nijkamp, Maaike; de Koeijer, Bjorn; Torn, Isaäc Anthony Robbert-Jan

    2018-01-01

    This study aims to address the structured implementation of sustainability considerations in packaging design processes by proposing a teaching framework for design students. The framework builds upon a four-year research program which aims to deliver insights regarding the environmental burden

  3. 7 CFR 3430.909 - Other considerations.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Other considerations. 3430.909 Section 3430.909 Agriculture Regulations of the Department of Agriculture (Continued) COOPERATIVE STATE RESEARCH, EDUCATION, AND EXTENSION SERVICE, DEPARTMENT OF AGRICULTURE COMPETITIVE AND NONCOMPETITIVE NON-FORMULA FEDERAL...

  4. Environmental approvals in New Brunswick : economic considerations

    Energy Technology Data Exchange (ETDEWEB)

    Marrack, C.; Maitland, R. [Suez Renewable Energy North America, Houston, TX (United States)

    2008-07-01

    This presentation provided a timeline of economic considerations related to New Brunswick's regulatory approval process for wind power developments. The economics of wind power projects require careful consideration during the initial planning phases, as it is not yet known if projects are viable. Spending in the early stages of a project should therefore be limited to items that focus on components of the environmental impact assessment (EIA) process that include establishing a relationship with First Nations groups in the area, and conducting seasonal bird studies. Economic considerations change when project viability is confirmed, and developers can then progress to conducting traditional knowledge studies and further seasonal bird studies. Baseline information studies should be reviewed, and biophysical surveys should involve the identification of any wetlands, sensitive areas, and rare plants. Archaeology studies are also required by the provincial government, as well as bat studies to determine if the site has a resident population of bats. Public and stakeholder consultations and open houses should then be held with an adequate time-frame for the submission of questions and concerns and the development of mitigation strategies. Project viability should be confirmed before power purchase agreements (PPAs) are signed. After PPAs are signed, the largest economic consideration is the schedule-related risk associated with legal and financial problems. It was concluded that noise impact, visual impact, and socioeconomic assessments and studies can be conducted after the PPA is secured. tabs., figs.

  5. Ethical Considerations for Data Collection Using Surveys.

    Science.gov (United States)

    Hammer, Marilyn J

    2017-03-01

    Surveys are widely used instruments to collect research data. Although surveys may appear relatively benign and easily unlinked to participants, considerations for the ethical conduct of research with surveys are important. Maintaining scientific rigor is essential. This article explores ethical tenets in relation to informed consent and scientific consent when using surveys.

  6. 44 CFR 331.4 - Special consideration.

    Science.gov (United States)

    2010-10-01

    ... HOMELAND SECURITY PREPAREDNESS PRESERVATION OF THE MOBILIZATION BASE THROUGH THE PLACEMENT OF PROCUREMENT... sells a significant proportion of its production to the Government is generally depressed or has a... hearing of interested parties, will give consideration to appropriate measures applicable to the entire...

  7. Design Criteria Based on Aesthetic Considerations

    DEFF Research Database (Denmark)

    Thomsen, Bente Dahl

    2009-01-01

    Aesthetic criteria for designs are often debated in a very subjective manner which makes it difficult to reach consensus. In order to have a more rational and transparent process, in particular in industrial design, we propose a procedure based on Baumgarten's aesthetic considerations and Thommesen......'s dividing of a form into form elements. The procedure has been tested in student projects....

  8. Adult Learners: Considerations for Education and Training

    Science.gov (United States)

    Kistler, Mark J.

    2011-01-01

    As more and more adults seek out education and training programs to help them become more competitive in the job market, it provides an opportunity for career and technical education. Those who teach adult learners should take into consideration their particular learning traits. This article highlights a framework of core principles to be…

  9. Some considerations on robotics for environmental friendliness

    International Nuclear Information System (INIS)

    Pin, F.G.

    1993-01-01

    This paper presents a series of considerations regarding the use and potential of robotic devices for supporting humans in a variety of tasks, while maintaining, if not improving, environmental friendliness. One of the main considerations brought forward here relates to the type of human-support functions which the robots are, or will be, expected to perform, and from this, a clear differentiation appears between robots designed to replace humans in environments that were engineered in the past for best human functionality, and robots designed to take functions in the future, in environments which could be better engineered for large-scale human-robot synergy. Other considerations discussed involve the ''life-cycle'' cleanliness of robotic systems, including the materials needs for their construction, their operation, their disposal and, more importantly, their energy consumption which will impact the cycle of natural resources utilization. These considerations are discussed using a variety of possible robotic systems applications in contexts varied as manufacturing, energy recovery and production, emergency situations handling, traffic improvement, waste management, agriculture, and space exploration. In all these applications, the operation costs and complexity of the robots seem to vary in inverse proportion to the amount of engineering that is feasible to make the task environment more robot-friendly, but with no seemingly direct impact on the potential for environmental friendliness of the robots

  10. 32 CFR 989.4 - Initial considerations.

    Science.gov (United States)

    2010-07-01

    ... alternatives analyzed in the environmental documents. (f) Pursue the objective of furthering foreign policy and... ENVIRONMENTAL IMPACT ANALYSIS PROCESS (EIAP) § 989.4 Initial considerations. Air Force personnel will: (a... CATEX from environmental impact analysis (appendix B). (c) Make environmental documents, comments, and...

  11. Topics for Current and Future Consideration

    Science.gov (United States)

    Pappas, James P.; Jerman, Jerry

    2011-01-01

    What lies ahead for nontraditional doctorate programs? What issues should concern administrators, faculty, and scholars? Faculty and administrators raised concerns that the marketplace demand for "nontraditional doctoral programs" would pollute the academic purity and sanctity of traditional programs. The authors provide some considerations for…

  12. Tube temperature rise limits: Boiling considerations

    Energy Technology Data Exchange (ETDEWEB)

    Vanderwater, R.G.

    1952-03-26

    A revision of tube power limits based on boiling considerations was presented earlier. The limits were given on a basis of tube power versus header pressure. However, for convenience of operation, the limits have been converted from tube power to permissible water temperature rise. The permissible {triangle}t`s water are given in this document.

  13. 20 CFR 332.2 - General considerations.

    Science.gov (United States)

    2010-04-01

    ... a female employee be considered to lack remuneration with respect to a day solely because of the... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false General considerations. 332.2 Section 332.2 Employees' Benefits RAILROAD RETIREMENT BOARD REGULATIONS UNDER THE RAILROAD UNEMPLOYMENT INSURANCE ACT...

  14. [From care to consideration of disabled people].

    Science.gov (United States)

    Chossy, Jean-François

    2014-05-01

    The law of 11th February 2005 relating to the equality of the rights and opportunities, participation and citizenship of disabled people was a major step forward. Nevertheless, more progress is needed to ensure more consideration is given to disabled people.

  15. Planning for an ageing population: strategic considerations

    LENUS (Irish Health Repository)

    O'Shea, Dr Eamon

    2005-01-01

    This report presents both the proceedings of the Council’s conference, Planning for an Ageing Population: Strategic Considerations, and the Council’s discussion paper, ‘The Older Population: Information Issues and Deficits’, which was introduced at that conference.\\r\

  16. Design considerations for mechanical face seals

    Science.gov (United States)

    Ludwig, L. P.; Greiner, H. F.

    1980-01-01

    Two companion reports deal with design considerations for improving performance of mechanical face seals, one of family of devices used in general area of fluid sealing of rotating shafts. One report deals with basic seal configuration and other with lubrication of seal.

  17. Transplanting the Body : Preliminary Ethical Considerations

    NARCIS (Netherlands)

    Miller, Lantz E.

    2017-01-01

    A dissociated area of medical research warrants bioethical consideration: a proposed transplantation of a donor’s entire body, except head, to a patient with a fatal degenerative disease. The seeming improbability of such an operation can only underscore the need for thorough bioethical assessment:

  18. 15 CFR 1160.4 - Antitrust considerations.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 3 2010-01-01 2010-01-01 false Antitrust considerations. 1160.4 Section 1160.4 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) TECHNOLOGY ADMINISTRATION, DEPARTMENT OF COMMERCE PRODUCTIVITY, TECHNOLOGY AND INNOVATION Promotion of...

  19. 15 CFR 1160.24 - Antitrust considerations.

    Science.gov (United States)

    2010-01-01

    ... Partnership Initiative § 1160.24 Antitrust considerations. (a) The Department of Commerce will offer no opinion on the antitrust merits of the formation of any proposed Strategic Partnership. The Department may..., conduct workshops to discuss the formation of such partnerships in general. Commerce will not select the...

  20. Some considerations on robotics for environmental friendliness

    Energy Technology Data Exchange (ETDEWEB)

    Pin, F.G.

    1993-12-01

    This paper presents a series of considerations regarding the use and potential of robotic devices for supporting humans in a variety of tasks, while maintaining, if not improving, environmental friendliness. One of the main considerations brought forward here relates to the type of human-support functions which the robots are, or will be, expected to perform, and from this, a clear differentiation appears between robots designed to replace humans in environments that were engineered in the past for best human functionality, and robots designed to take functions in the future, in environments which could be better engineered for large-scale human-robot synergy. Other considerations discussed involve the ``life-cycle`` cleanliness of robotic systems, including the materials needs for their construction, their operation, their disposal and, more importantly, their energy consumption which will impact the cycle of natural resources utilization. These considerations are discussed using a variety of possible robotic systems applications in contexts varied as manufacturing, energy recovery and production, emergency situations handling, traffic improvement, waste management, agriculture, and space exploration. In all these applications, the operation costs and complexity of the robots seem to vary in inverse proportion to the amount of engineering that is feasible to make the task environment more robot-friendly, but with no seemingly direct impact on the potential for environmental friendliness of the robots.

  1. Davedan Show Di Amphi Theatre Nusa Dua Bali

    Directory of Open Access Journals (Sweden)

    Ni Made Ruastiti

    2018-05-01

    Bali karena berimplikasi positif pada ekonomi para pihak terkait, pengayaan bagi seni pertunjukan daerah setempat, dan identitas bagi kawasan wisata Nusa Dua, Bali. This article was compiled from the research results that aimed to understand the Davedan Show at Amphi Theater Nusa Dua, Bali. This research was conducted due to the imbalance between the assumption and the reality in real life. Generally, tourists visiting Bali are more excited and enthusiastic to watch the tourism performing arts that are based on local traditional art and culture. However, the reality is different. The questions are: how is the form of the Davedan show?; why do the tourists enjoy watching the show ?; what are the implications for the performer, the society, and the tourism industry in Nusa Dua, Bali?. This research applied qualitative research methods, especially the participative implementation that prioritized cooperation between the researchers and the related informants. The data sources of the research were the Davedan show, management, dancers, audiences, and similar research results produced by previous researchers. All data that had been collected by observation, interview, FGD, and literature study were then analyzed with aesthetic postmodern theory, theory of practice, and theory of power relationship. The results showed that: (1 Davedan Show was presented with the concept of a new presentation in the tourism performing arts in Bali. It could be seen from the material, the form, the way of presentation, and the management of the show. Davedan Show, presenting the theme of Treasure of the Archipelago and opening the new adventure gate, was accompanied by ethnic music recordings of the archipelago in a medley then continued with the performance structures of: Balinese, Sumatran, Sundanese, Solo, Borneo and Papuan art and culture; (2 Davedan Show attracted many foreign tourists because the show was based on the existence of market, aesthetic, and cultural ideologies of the

  2. Special Consideration in Post-Secondary Institutions: Trends at a Canadian University

    Science.gov (United States)

    Zimmermann, Joelle; Kamenetsky, Stuart B.; Pongracic, Syb

    2015-01-01

    This study examined trends in the practice of granting special consideration for missed tests and late papers in colleges and universities. We analyzed a database of 4,183 special consideration requests at a large Canadian university between 1998 and 2008. Results show a growing rate of requests per enrolment between 2001 and 2007. Although…

  3. The Biochemistry Show: a new and fun tool for learning

    Directory of Open Access Journals (Sweden)

    A.H Ono

    2006-07-01

    Full Text Available The traditional methods to teach biochemistry in most universities are based on the memorization of chemical structures,  biochemical  pathways  and  reagent  names,  which  is  many  times  dismotivating  for  the  students.  We presently describe an innovative, interactive and alternative method for teaching biochemistry to medical and nutrition undergraduate students, called the Biochemistry Show (BioBio Show.The Biobio show is based on active participation of the students. They are divided in groups and the groups face each other. One group faces another one group at a time, in a game based on true or false questions that involve subjects of applied biochemistry (exercise, obesity, diabetes, cholesterol, free radicals, among others. The questions of the Show are previously elaborated by senior students. The Biobio Show has four phases, the first one is a selection exam, and from the second to the fourth phase, eliminatory confrontations happen. On a confrontation, the first group must select a certain quantity of questions for the opponent to answer.  The group who choses the questions must know how to answer and justify the selected questions. This procedure is repeated on all phases of the show. On the last phase, the questions used are taken from an exam previously performed by the students: either the 9-hour biochemistry exam (Sé et al. A 9-hour biochemistry exam. An iron man competition or a good way of evaluating undergraduate students? SBBq 2005, abstract K-6 or the True-or-False exam (TFE (Sé et al. Are tutor-students capable of writing good biochemistry exams? SBBq 2004, abstract K-18. The winner group receives an extra 0,5 point on the final grade. Over 70% of the students informed on a questionnaire that the Biobio Show is a valuable tool for learning biochemistry.    That is a new way to enrich the discussion of biochemistry in the classroom without the students getting bored. Moreover, learning

  4. Five Kepler target stars that show multiple transiting exoplanet candidates

    Energy Technology Data Exchange (ETDEWEB)

    Steffen, Jason H.; /Fermilab; Batalha, Natalie M.; /San Jose State U.; Borucki, William J.; /NASA, Ames; Buchhave, Lars A.; /Harvard-Smithsonian Ctr. Astrophys. /Bohr Inst.; Caldwell, Douglas A.; /NASA, Ames /SETI Inst., Mtn. View; Cochran, William D.; /Texas U.; Endl, Michael; /Texas U.; Fabrycky, Daniel C.; /Harvard-Smithsonian Ctr. Astrophys.; Fressin, Francois; /Harvard-Smithsonian Ctr. Astrophys.; Ford, Eric B.; /Florida U.; Fortney, Jonathan J.; /UC, Santa Cruz, Phys. Dept. /NASA, Ames

    2010-06-01

    We present and discuss five candidate exoplanetary systems identified with the Kepler spacecraft. These five systems show transits from multiple exoplanet candidates. Should these objects prove to be planetary in nature, then these five systems open new opportunities for the field of exoplanets and provide new insights into the formation and dynamical evolution of planetary systems. We discuss the methods used to identify multiple transiting objects from the Kepler photometry as well as the false-positive rejection methods that have been applied to these data. One system shows transits from three distinct objects while the remaining four systems show transits from two objects. Three systems have planet candidates that are near mean motion commensurabilities - two near 2:1 and one just outside 5:2. We discuss the implications that multitransiting systems have on the distribution of orbital inclinations in planetary systems, and hence their dynamical histories; as well as their likely masses and chemical compositions. A Monte Carlo study indicates that, with additional data, most of these systems should exhibit detectable transit timing variations (TTV) due to gravitational interactions - though none are apparent in these data. We also discuss new challenges that arise in TTV analyses due to the presence of more than two planets in a system.

  5. Retrieving unobserved consideration sets from household panel data

    NARCIS (Netherlands)

    J.E.M. van Nierop; R. Paap (Richard); B. Bronnenberg; Ph.H.B.F. Franses (Philip Hans); M. Wedel (Michel)

    2005-01-01

    textabstractWe propose a new model to describe consideration, consisting of a multivariate probit model component for consideration and a multinomial probit model component for choice, given consideration. The approach allows one to analyze stated consideration set data, revealed consideration set

  6. A consideration on Public Nuclear Energy Acceptance

    International Nuclear Information System (INIS)

    Seki, Yosinobu

    1998-01-01

    PA (Public Acceptance for Nuclear Energy) has been discussed so long time. Much of people understood, it is so important, but they understood, it has not existed with good evaluation method. Only saying, it is necessary to distribute a correct knowledge to public, but how we can do? It is hard to do. Saying inside talking to others, teach speaking for the people, or showing on the same stage opposite people and understandable people. They do not fit the purpose. First key word is curiosity, 2nd one is the intelligence circle, instead of unusable knowledge and third one is the long time continuation. To do actual should consider on the sounding circumstance and the feeling of person to talk. To find the way is very complicated and difficult to do. The second cartoon has been published for high-level waste burying. (author)

  7. Fairness requires deliberation: The primacy of economic over social considerations

    Directory of Open Access Journals (Sweden)

    Guy eHochman

    2015-06-01

    Full Text Available While both economic and social considerations of fairness and equity play an important role in financial decision-making, it is not clear which of these two motives is more primal and immediate and which one is secondary and slow. Here we used variants of the ultimatum game to examine this question. Experiment 1 shows that acceptance rate of unfair offers increases when participants are asked to base their choice on their gut-feelings, as compared to when they thoroughly consider the available information. In line with these results, Experiments 2 and 3 provide process evidence that individuals prefer to first examine economic information about their own utility rather than social information about equity and fairness, even at the price of foregoing such social information. Our results suggest that people are more economically rational at the core, but social considerations (e.g., inequality aversion require deliberation, which under certain conditions override their self-interested impulses.

  8. Fairness requires deliberation: the primacy of economic over social considerations

    Science.gov (United States)

    Hochman, Guy; Ayal, Shahar; Ariely, Dan

    2015-01-01

    While both economic and social considerations of fairness and equity play an important role in financial decision-making, it is not clear which of these two motives is more primal and immediate and which one is secondary and slow. Here we used variants of the ultimatum game to examine this question. Experiment 1 shows that acceptance rate of unfair offers increases when participants are asked to base their choice on their gut-feelings, as compared to when they thoroughly consider the available information. In line with these results, Experiments 2 and 3 provide process evidence that individuals prefer to first examine economic information about their own utility rather than social information about equity and fairness, even at the price of foregoing such social information. Our results suggest that people are more economically rational at the core, but social considerations (e.g., inequality aversion) require deliberation, which under certain conditions override their self-interested impulses. PMID:26106342

  9. Fairness requires deliberation: the primacy of economic over social considerations.

    Science.gov (United States)

    Hochman, Guy; Ayal, Shahar; Ariely, Dan

    2015-01-01

    While both economic and social considerations of fairness and equity play an important role in financial decision-making, it is not clear which of these two motives is more primal and immediate and which one is secondary and slow. Here we used variants of the ultimatum game to examine this question. Experiment 1 shows that acceptance rate of unfair offers increases when participants are asked to base their choice on their gut-feelings, as compared to when they thoroughly consider the available information. In line with these results, Experiments 2 and 3 provide process evidence that individuals prefer to first examine economic information about their own utility rather than social information about equity and fairness, even at the price of foregoing such social information. Our results suggest that people are more economically rational at the core, but social considerations (e.g., inequality aversion) require deliberation, which under certain conditions override their self-interested impulses.

  10. Migraine patients consistently show abnormal vestibular bedside tests

    Directory of Open Access Journals (Sweden)

    Eliana Teixeira Maranhão

    2015-01-01

    Full Text Available Migraine and vertigo are common disorders, with lifetime prevalences of 16% and 7% respectively, and co-morbidity around 3.2%. Vestibular syndromes and dizziness occur more frequently in migraine patients. We investigated bedside clinical signs indicative of vestibular dysfunction in migraineurs.Objective To test the hypothesis that vestibulo-ocular reflex, vestibulo-spinal reflex and fall risk (FR responses as measured by 14 bedside tests are abnormal in migraineurs without vertigo, as compared with controls.Method Cross-sectional study including sixty individuals – thirty migraineurs, 25 women, 19-60 y-o; and 30 gender/age healthy paired controls.Results Migraineurs showed a tendency to perform worse in almost all tests, albeit only the Romberg tandem test was statistically different from controls. A combination of four abnormal tests better discriminated the two groups (93.3% specificity.Conclusion Migraine patients consistently showed abnormal vestibular bedside tests when compared with controls.

  11. Strategies for controlling acid rain: economic considerations

    International Nuclear Information System (INIS)

    Forster, B.A.; Crocker, T.D.

    1992-01-01

    There are two competing approaches to reducing pollution such as the acid rain precursors SOsub(2) and NOsub(x). In the command and control approach, pollution control legislation may dictate the technological method by which specified pollution reductions are to be achieved. A key feature of command-and-control regulations is their inflexibility. The alternative approach relies on market mechanisms and incentives to induce firms to reduce pollution voluntarily. Economists generally prefer this approach because it permits flexibility for firms in selecting abatement methods to minimize costs. This chapter deals with qualitative issues in determining and achieving an ''optimal'' pollution level using various taxes, subsidies or quantitative restrictions. Alternative permit schemes for achieving regional pollution control are considered. Statistical studies are discussed which compare the command-and-control approach with the economic incentives approach and show that there are substantial cost differences between them in most cases. Finally, some institutional factors, that may lead to more costly acid rain control schemes being selected, are examined. A list of 61 references is appended. (UK)

  12. [Vitreoretinal outpatient surgery: clinical and financial considerations].

    Science.gov (United States)

    Creuzot-Garcher, C; Aubé, H; Candé, F; Dupont, G; Guillaubey, A; Malvitte, L; Arnavielle, S; Bron, A

    2008-11-01

    Vitreoretinal surgery has benefited from great advances opening the opportunity for outpatient management. We report on the 6-month experience of outpatient surgery for vitreoretinal diseases. From November 2007 to April 2008, 270 patients benefited from a vitreoretinal surgery, with 173 retinal detachments, 63 epiretinal membranes, and 34 other procedures. Only 8.5% (n=23) of the patients had to stay at the hospital one or two nights. The main reasons were the distance from the hospital and surgery on a single-eye patient. The questionnaire given after the surgery showed that almost all the patients were satisfied with the outpatient setting. In contrast, the financial results showed a loss of income of around 400,000 euros due to the low level of payment of outpatient surgery in France by the national health insurance system. Vitreoretinal surgery can be achieved in outpatient surgery with an improvement in the information given to the patients and the overall organization of the hospitalization. However, the current income provided with vitreoretinal outpatient surgery is highly disadvantageous in France, preventing this method from being generalized.

  13. [{sup 18}F]FETO: metabolic considerations

    Energy Technology Data Exchange (ETDEWEB)

    Ettlinger, Dagmar E.; Machek, Michael; Rendl, Gundula; Karanikas, Georgios; Kletter, Kurt [Medical University of Vienna, Department of Nuclear Medicine, Vienna (Austria); Wadsak, Wolfgang; Dudczak, Robert [Medical University of Vienna, Department of Nuclear Medicine, Vienna (Austria); Ludwig-Boltzmann-Institute for Nuclear Medicine, Vienna (Austria); Mien, Leonhard-Key [Medical University of Vienna, Department of Nuclear Medicine, Vienna (Austria); University of Vienna, Department of Pharmaceutic Technology and Biopharmaceutics, Vienna (Austria); Medical University of Vienna, Department of Psychiatry, Vienna (Austria); Wabnegger, Leila [Medical University of Vienna, Department of Nuclear Medicine, Vienna (Austria); Medical University of Vienna, Department of Psychiatry, Vienna (Austria); Viernstein, Helmut [University of Vienna, Department of Pharmaceutic Technology and Biopharmaceutics, Vienna (Austria); Mitterhauser, Markus [Medical University of Vienna, Department of Nuclear Medicine, Vienna (Austria); University of Vienna, Department of Pharmaceutic Technology and Biopharmaceutics, Vienna (Austria); Hospital Pharmacy of the General Hospital of Vienna, Vienna (Austria)

    2006-08-15

    11{beta}-Hydroxylase is a key enzyme in the biosynthesis of adrenocortical steroid hormones and is a suitable target for the imaging of the adrenal cortex. [{sup 11}C]Metomidate (MTO), [{sup 11}C]etomidate (ETO) and desethyl-[{sup 18}F]fluoroethyl-etomidate (FETO) are potent inhibitors of this enzyme and are used for PET imaging of adrenocortical pathologies. The aims of this study were (1) to evaluate and compare the metabolic stability of MTO, ETO and FETO against esterases and (2) to investigate the metabolic pattern of FETO in vivo. In vitro assays were performed using different concentrations of MTO, ETO and FETO with constant concentrations of carboxylesterase. Human in vivo studies were performed with human blood samples drawn from the cubital vein. After sample clean-up, the serum was analysed by HPLC methods. In vitro assays showed Michaelis-Menten constants of 115.1 {mu}mol for FETO, 162.0 {mu}mol for MTO and 168.6 {mu}mol for ETO. Limiting velocities were 1.54 {mu}mol/min (FETO), 1.47 {mu}mol/min (MTO) and 1.35 {mu}mol/min (ETO). This implies insignificantly decreased esterase stability of FETO compared with MTO and ETO. In vivo investigations showed a rapid metabolisation of FETO within the first 10 min (2 min: 91.41%{+-}6.44%, n=6; 10 min: 23.78%{+-}5.54%, n=4) followed by a smooth decrease in FETO from 20 to 90 min (20 min: 11.23%{+-}3.79% n=4; 90 min: 3.68%{+-}3.65%, n=4). Recovery rate was 61.43%{+-}3.19% (n=12). In vitro experiments demonstrated that FETO stability against esterases is comparable to that of ETO and MTO. The metabolic profile showed that FETO kinetics in humans are fast. (orig.)

  14. Considerations on the time factor in radiobiology

    International Nuclear Information System (INIS)

    Rossi, H.H.

    1981-01-01

    Although extension of the time period during which a given dose of radiation is administered commonly reduces effectiveness, there are well established instances where the reverse is true. Theoretical considerations are presented which relate reduction or enhancement to the shape of the dose-effect curve. While in many instances these changes of sensitivity may be due to intracellular processes it appears that in the case of carcinogenesis by low doses of neutrons, time dependent intercellular action must be involved. (orig.) [de

  15. Local anesthesia in dentistry - Clinical Considerations

    OpenAIRE

    Sharmraaj Subramaniam; Prasanna Neelakantan

    2013-01-01

    Local anaesthesia is commonly employed prior to most dental procedures. It is imperative to understand the mechanisms by which local anaesthetics work, so that their efficacy can be improved for painless dental care. Local anaesthesia also has major clinical implications in that it can precipitate emergencies in patients with an underlying systemic disease. It is imperative that a dentist have a thorough knowledge of the considerations one must take when administering local anaesthesia in pat...

  16. Local Anesthetics: Review of Pharmacological Considerations

    Science.gov (United States)

    Becker, Daniel E; Reed, Kenneth L

    2012-01-01

    Local anesthetics have an impressive history of efficacy and safety in medical and dental practice. Their use is so routine, and adverse effects are so infrequent, that providers may understandably overlook many of their pharmacotherapeutic principles. The purpose of this continuing education article is to provide a review and update of essential pharmacology for the various local anesthetic formulations in current use. Technical considerations will be addressed in a subsequent article. PMID:22822998

  17. Paediatricians, social media and blogs: Ethical considerations

    OpenAIRE

    St-Laurent-Gagnon, Thérèse; Coughlin, Kevin W

    2012-01-01

    The use of blogs, Facebook and similar social networking sites is rapidly expanding and, when compared with e-mail, may be having a significantly different impact on the traditional doctor-patient relationship. Characteristics specific to these online platforms have major implications for professional relationships, including the ‘Facebook effect’ (the relative permanence of postings) and the ‘online disinhibition effect’. The present practice point illustrates relevant ethical considerations...

  18. Landscaping Considerations for Urban Stream Restoration Projects

    National Research Council Canada - National Science Library

    Bailey, Pam

    2004-01-01

    ... after restoration and its functionality for public use. The landscaping component of such stream and riparian restoration projects must be emphasized given its importance of visual success and public perception. The purpose of this technical note is to address landscaping considerations associated with urban stream and riparian restoration projects, and provide ideas to managers for enhancing the visual appeal and aesthetic qualities of urban projects.

  19. Considerations on automation of coating machines

    Science.gov (United States)

    Tilsch, Markus K.; O'Donnell, Michael S.

    2015-04-01

    Most deposition chambers sold into the optical coating market today are outfitted with an automated control system. We surveyed several of the larger equipment providers, and nine of them responded with information about their hardware architecture, data logging, level of automation, error handling, user interface, and interfacing options. In this paper, we present a summary of the results of the survey and describe commonalities and differences together with some considerations of tradeoffs, such as between capability for high customization and simplicity of operation.

  20. Stress and food allergy: mechanistic considerations

    OpenAIRE

    Schreier, Hannah M.C.; Wright, Rosalind J.

    2013-01-01

    Recent years have seen a marked increase in food allergy prevalence among children, particularly in Western countries, that cannot be explained by genetic factors alone. This has resulted in an increased effort to identify environmental risk factors underlying food allergies and to understand how these factors may be modified through interventions. Food allergy is an immune-mediated adverse reaction to food. Consequently, considerations of candidate risk factors have begun to focus on environ...

  1. Manufacturing considerations for AMLCD cockpit displays

    Science.gov (United States)

    Luo, Fang-Chen

    1995-06-01

    AMLCD cockpit displays need to meet more stringent requirements compared with AMLCD commercial displays in areas such as environmental conditions, optical performance and device reliability. Special considerations are required for the manufacturing of AMLCD cockpit displays in each process step to address these issues. Some examples are: UV stable polarizers, wide-temperature LC material, strong LC glue seal, ESS test system, gray scale voltage EEPROM, etc.

  2. Human Genome Editing and Ethical Considerations.

    Science.gov (United States)

    Krishan, Kewal; Kanchan, Tanuj; Singh, Bahadur

    2016-04-01

    Editing human germline genes may act as boon in some genetic and other disorders. Recent editing of the genome of the human embryo with the CRISPR/Cas9 editing tool generated a debate amongst top scientists of the world for the ethical considerations regarding its effect on the future generations. It needs to be seen as to what transformation human gene editing brings to humankind in the times to come.

  3. Reactor design considerations for inertial confinement fusion

    International Nuclear Information System (INIS)

    Booth, L.A.

    1979-01-01

    The most challenging reactor design consideration is protection of the cavity wall from the various energy forms as released by the pellet and as affected by the reaction-chamber phenomena. These phenomena depend on both the design and the yield of the pellet, as well as on ambient conditions in the chamber at the time of the pellet microexplosion. The effects on pellet energy-release mechanisms of various reaction chamber atmosphere options are summarized

  4. General aspects of siting and safety considerations

    International Nuclear Information System (INIS)

    Rutgers, E.

    1980-01-01

    The siting process from site selection to the different stages of review by the regulatory body is described. Special attention is payed to the role and responsibilities of the licensing authority. Next, the basic considerations involved in the siting process are reviewed. They include system planning, engineering, safety, environmental impact (including land use) and economics. Case studies illustrating different aspects of the siting process (e.g. site selection) are presented. (orig.)

  5. Patient Dose Considerations in Interventional Cardiology

    International Nuclear Information System (INIS)

    Ciraj-Bjelac, O.; Rafajlovic, S.; Arandjic, D.; Kosutic, D.

    2011-01-01

    Interventional cardiology procedures are classified as high-dose procedures, owing to increased risk for radiation skin injuries and stochastic effects, such as cancer. European MED Directive 97/43 requires special consideration and dose evaluation for this kind of procedures . Dose received by a patient, in general, depends on the radiological equipment, examination protocol, the way it is implemented, the patient's body weight and nature of disease. Long-term fluoroscopy of certain parts of the body, a significant body mass, high-value dose intensity, continuous rather than pulsed fluoroscopy, small focus-skin distance and repeated procedure on the same patient, are among the factors that can lead to radiation skin injuries. A particular challenge is the fact that the radiation damage of the skin is difficult to detect and connect to the previously conducted cardiologic procedures. The fact that such injuries do not have immediate manifestation is very often reason that many of them remain undetected. The purpose of this work is to assess the level of radiation dose to patients in percutaneous coronary interventions (PCI) and to investigate possibility for setting of a practical trigger value if dose quantities exceed certain levels in terms of dose descriptors available at display of interventional cardiology unit. Two dedicated interventional cardiology units in a large teaching cardiac centre (Clinical Centre of Serbia, Belgrade, Serbia) were included in the survey. Both rooms (D and F) were equipped with X-ray units of the identical model: Siemens Axiom Artis (Siemens, Erlangen, Germany) with the flat panel detector and integrated ionization chamber to measure air kerma-area product (P K A) and air kerma in international reference point (K I RP). Patient doses were assessed in terms of P K A, K I RP and maximum-skin dose (MSD). P K A and K I RP were assessed using a built-in, in situ calibrated dosimeters, while MSD was estimated using radiochromic films

  6. Cultural Differences in Opportunity Cost Consideration.

    Science.gov (United States)

    Zhang, Ning; Ji, Li-Jun; Li, Ye

    2017-01-01

    Two studies were conducted to investigate cultural differences in opportunity cost consideration between Chinese and Euro-Canadians. Opportunity cost is defined as the cost of a benefit that must be forgone in order to pursue a better alternative (Becker et al., 1974). In both studies, participants read about hypothetical purchase scenarios, and then decided whether they would buy a certain product. Opportunity cost consideration was measured in two ways: (1) participants' thoughts pertaining to other (nonfocal) products while making decisions; (2) participants' decisions not to buy a focal product (Study 1) or a more expensive product (Study 2). Across both indexes, we found that after controlling for individual difference variables and amount of pocket money, Chinese participants in China considered financial opportunity cost more than Euro-Canadians in Study 1. Similar results were observed in Study 2 when comparing Chinese in Canada with Euro-Canadians However, the cultural effect on opportunity cost consideration was confounded by family income in Study 2. Implications for resource management, limitations of the current research and directions for future research are discussed.

  7. Considerations on the modelling of environmental radiocarbon

    International Nuclear Information System (INIS)

    Scott, E.M.; McCartney, M.

    1991-01-01

    Modelling radionuclide transfer within the natural environment involves three general steps: model formulation, its fitting using appropriate experimental data and model validation. The last process typically involves a sensitivity analysis and is used to modify model formulation and to direct future experimental effort. A wide variety of models exists appropriate to a number of different applications. Recently, attention has been directed to the development of principles for establishing local, regional and global upper bounds to doses. Here important considerations in model choice are the spatial detail required within the model, the links between models of differing resolution and the availability of suitable experimental data. We illustrate the model-building stages and discuss the above considerations in transfer modelling using radiocarbon which is produced and released as part of the nuclear fuel cycle. Its long half life of 5730 years, its mobility in the environment and its incorporation into man via the food chain make it of some considerable radiological significance. We consider local modelling of 14 C transfer using a Gaussian plume model, while its global dispersal is modelled using a large globally-averaged compartmental model. The global analysis is used to make short term predictions of 14 C specific activities to 2050 and longer-term predictions over a period of 10,000 years. We discuss the validation of these models and attempt to quantify the sources and magnitudes of the uncertainties in the model predictions. (26 refs., 2 figs.)

  8. Environmental considerations in physical planning in Norway and Poland

    Energy Technology Data Exchange (ETDEWEB)

    Naess, P; Saglie, I L; Glowacki, W; Dunin-Woyseth, H

    1998-12-31

    As a part of an agreement on environmental cooperation between Norway and Eastern Europe, a comparative case study was carried out of environmental considerations in physical planning since 1968 in the Norwegian municipality of Sandefjord and the Polish municipality of Myslenice. This report discusses the final results. Land use planning is surprisingly similar in the two countries. In both, the plans emphasize the protection of farmland and scarce biotopes as well as sewage management. In Myslenice, a major concern has been cultural heritage and cultural landscapes while in Sandefjord attention was paid more to natural areas for outdoor recreation. In both cases there has been little focus on energy conservation and the concept of sustainable development has hardly been discussed. The plans have been considerably influenced by national environmental policies. The type of political system, capitalism vs. state socialism, has indirectly influenced the amount of construction and hence the pace of conversion of undeveloped land, but does not appear to have had much impact on the environmental content of the plans. The emphasis laid on various environmental issues in part reflects the actual local challenges, but also cross-national cultural differences and the fact that during the period the environmental agenda has been widened in both municipalities, most clearly seen in the case of Sandefjord. The plans seem to have been considerably influenced by professional ideals, knowledge and methods common among planners across national boundaries. 52 refs., 1 figure, 2 tabs.

  9. Considerations in the development of subsurface containment barrier performance standards

    International Nuclear Information System (INIS)

    Dunstan, S.; Zdinak, A.P.; Lodman, D.

    1997-01-01

    The U.S. Department of Energy (DOE) is supporting subsurface barriers as an alternative remedial option for management of contamination problems at their facilities. Past cleanup initiatives have sometimes proven ineffective or extremely expensive. Economic considerations coupled with changing public and regulatory philosophies regarding remediation techniques makes subsurface barriers a promising technology for future cleanup efforts. As part of the initiative to develop subsurface containment barriers as an alternative remedial option, DOE funded MSE Technology Applications, Inc. (MSE) to conduct a comprehensive review to identify performance considerations for the acceptability of subsurface barrier technologies as a containment method. Findings from this evaluation were intended to provide a basis for selection and application of containment technologies to address waste problems at DOE sites. Based on this study, the development of performance standards should consider: (1) sustainable low hydraulic conductivity; (2) capability to meet applicable regulations; (3) compatibility with subsurface environmental conditions; (4) durability and long-term stability; (5) repairability; and (6) verification and monitoring. This paper describes the approach for determining considerations for performance standards

  10. Environmental considerations in physical planning in Norway and Poland

    Energy Technology Data Exchange (ETDEWEB)

    Naess, P.; Saglie, I.L.; Glowacki, W.; Dunin-Woyseth, H.

    1997-12-31

    As a part of an agreement on environmental cooperation between Norway and Eastern Europe, a comparative case study was carried out of environmental considerations in physical planning since 1968 in the Norwegian municipality of Sandefjord and the Polish municipality of Myslenice. This report discusses the final results. Land use planning is surprisingly similar in the two countries. In both, the plans emphasize the protection of farmland and scarce biotopes as well as sewage management. In Myslenice, a major concern has been cultural heritage and cultural landscapes while in Sandefjord attention was paid more to natural areas for outdoor recreation. In both cases there has been little focus on energy conservation and the concept of sustainable development has hardly been discussed. The plans have been considerably influenced by national environmental policies. The type of political system, capitalism vs. state socialism, has indirectly influenced the amount of construction and hence the pace of conversion of undeveloped land, but does not appear to have had much impact on the environmental content of the plans. The emphasis laid on various environmental issues in part reflects the actual local challenges, but also cross-national cultural differences and the fact that during the period the environmental agenda has been widened in both municipalities, most clearly seen in the case of Sandefjord. The plans seem to have been considerably influenced by professional ideals, knowledge and methods common among planners across national boundaries. 52 refs., 1 figure, 2 tabs.

  11. Design Considerations of Permanent Magnet Transverse Flux Machines

    DEFF Research Database (Denmark)

    Lu, Kaiyuan; Rasmussen, Peter Omand; Ritchie, Ewen

    2011-01-01

    electrical machines. This paper addresses two important design considerations for PMTFM—the influence of permanent magnet leakage flux, which plays an important role in the determination of machine output torque, and the leakage inductance. A new simple method to provide a quick estimation of the armature......Permanent magnet transverse flux machine (PMTFM) is well known for its high torque density and is interested in various direct-drive applications. Due to its complicated 3-D flux components, design and design optimization of a PMTFM is more difficult and time consuming than for radial flux...

  12. Rhabdomyosarcoma cells show an energy producing anabolic metabolic phenotype compared with primary myocytes

    Directory of Open Access Journals (Sweden)

    Higashi Richard M

    2008-10-01

    Full Text Available Abstract Background The functional status of a cell is expressed in its metabolic activity. We have applied stable isotope tracing methods to determine the differences in metabolic pathways in proliferating Rhabdomysarcoma cells (Rh30 and human primary myocytes in culture. Uniformly 13C-labeled glucose was used as a source molecule to follow the incorporation of 13C into more than 40 marker metabolites using NMR and GC-MS. These include metabolites that report on the activity of glycolysis, Krebs' cycle, pentose phosphate pathway and pyrimidine biosynthesis. Results The Rh30 cells proliferated faster than the myocytes. Major differences in flux through glycolysis were evident from incorporation of label into secreted lactate, which accounts for a substantial fraction of the glucose carbon utilized by the cells. Krebs' cycle activity as determined by 13C isotopomer distributions in glutamate, aspartate, malate and pyrimidine rings was considerably higher in the cancer cells than in the primary myocytes. Large differences were also evident in de novo biosynthesis of riboses in the free nucleotide pools, as well as entry of glucose carbon into the pyrimidine rings in the free nucleotide pool. Specific labeling patterns in these metabolites show the increased importance of anaplerotic reactions in the cancer cells to maintain the high demand for anabolic and energy metabolism compared with the slower growing primary myocytes. Serum-stimulated Rh30 cells showed higher degrees of labeling than serum starved cells, but they retained their characteristic anabolic metabolism profile. The myocytes showed evidence of de novo synthesis of glycogen, which was absent in the Rh30 cells. Conclusion The specific 13C isotopomer patterns showed that the major difference between the transformed and the primary cells is the shift from energy and maintenance metabolism in the myocytes toward increased energy and anabolic metabolism for proliferation in the Rh30 cells

  13. Liquid metal corrosion considerations in alloy development

    International Nuclear Information System (INIS)

    Tortorelli, P.F.; DeVan, J.H.

    1984-01-01

    Liquid metal corrosion can be an important consideration in developing alloys for fusion and fast breeder reactors and other applications. Because of the many different forms of liquid metal corrosion (dissolution, alloying, carbon transfer, etc.), alloy optimization based on corrosion resistance depends on a number of factors such as the application temperatures, the particular liquid metal, and the level and nature of impurities in the liquid and solid metals. The present paper reviews the various forms of corrosion by lithium, lead, and sodium and indicates how such corrosion reactions can influence the alloy development process

  14. NPP control command: Considerations for the future

    International Nuclear Information System (INIS)

    Trapp, J.P.

    1998-01-01

    Recent years have seen considerable improvements in the performance available from instrumentation, computerized data acquisition and processing systems, signal processing and related display processing systems. This progress implies the need for a complete rethink of the approach to future surveillance, control and protection systems for use with nuclear reactors, especially regarding new reactor systems. These new systems will in the future need to ensure full compatibility between safety improvements and the enhanced economic competitively of nuclear power. This paper presents an exercise covering the main functions that can as of now be considered for future applications in this field. (author)

  15. Consideration of Fugitive Emissions from Grain Elevators

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  16. Safety considerations in the design of PFBR

    International Nuclear Information System (INIS)

    Vaidyanathan, G.; Om Pal Singh; Govindarajan, S.; Chellapandi, P.; Chetal, S.C.; Shankar Singh, R.; Bhoje, S.B.

    1996-01-01

    Prototype Fast Breeder Reactor (PFBR) is a 500 MWe reactor under design in India. The overall safety approach adopted is based on the defence-in-depth principle. Design features have been incorporated to minimize occurrence of unsafe conditions. A plant protection system comprising reliable core monitoring to detect the off-normal condition, a reliable shutdown system to ensure safe shutdown and a passive decay heat removal system are provided. Containment is provided to prevent any release of radioactivity to the environment in case of failure of the protective devices. This paper provides a brief outline of the safety considerations in the design of PFBR. (author). 5 refs, 1 tab

  17. Aesthetic considerations in algorithmic and generative composition

    Science.gov (United States)

    Hagan, Kerry L.

    Models of chance operations, random equations, stochastic processes, and chaos systems have inspired composers as historical as Wolfgang Amadeus Mozart. As these models advance and new processes are discovered or defined, composers continue to find new inspirations for musical composition. Yet, the relative artistic merits of some of these works are limited. This paper explores the application of extra-musical processes to the sonic arts and proposes aesthetic considerations from the point of view of the artist. Musical examples demonstrate possibilities for working successfully with algorithmic and generative processes in sound, from formal decisions to synthesis.

  18. Chemical considerations in severe accident analysis

    International Nuclear Information System (INIS)

    Malinauskas, A.P.; Kress, T.S.

    1988-01-01

    The Reactor Safety Study presented the first systematic attempt to include fission product physicochemical effects in the determination of expected consequences of hypothetical nuclear reactor power plant accidents. At the time, however, the data base was sparse, and the treatment of fission product behavior was not entirely consistent or accurate. Considerable research has since been performed to identify and understand chemical phenomena that can occur in the course of a nuclear reactor accident, and how these phenomena affect fission product behavior. In this report, the current status of our understanding of the chemistry of fission products in severe core damage accidents is summarized and contrasted with that of the Reactor Safety Study

  19. Criticality safety and facility design considerations

    International Nuclear Information System (INIS)

    Waltz, W.R.

    1991-06-01

    Operations with fissile material introduce the risk of a criticality accident that may be lethal to nearby personnel. In addition, concerns over criticality safety can result in substantial delays and shutdown of facility operations. For these reasons, it is clear that the prevention of a nuclear criticality accident should play a major role in the design of a nuclear facility. The emphasis of this report will be placed on engineering design considerations in the prevention of criticality. The discussion will not include other important aspects, such as the physics of calculating limits nor criticality alarm systems

  20. Justification and radiology: Some ethical considerations

    International Nuclear Information System (INIS)

    Sia, S.

    2009-01-01

    This paper, which seeks to address the issue of justification in radiology, intends firstly to comment on the current discussion of the ethical foundation of radiological practice that focuses on the move from utilitarianism to the rights-centred criterion. Secondly, and this constitutes the bulk of the paper, it aims to offer a philosophical perspective, which is hoped will lead to a consideration of certain specific areas in ethical decision-making in the attempts here to deal with the main issue of justification in radiology. (authors)

  1. Implantable intraocular pressure monitoring systems: Design considerations

    KAUST Repository

    Arsalan, Muhammad; Ouda, Mahmoud H.; Marnat, Loic; Shamim, Atif; Salama, Khaled N.

    2013-01-01

    Design considerations and limitations of implantable Intraocular Pressure Monitoring (IOPM) systems are presented in this paper. Detailed comparison with the state of the art is performed to highlight the benefits and challenges of the proposed design. The system-on-chip, presented here, is battery free and harvests energy from incoming RF signals. This low-cost design, in standard CMOS process, does not require any external components or bond wires to function. This paper provides useful insights to the designers of implantable wireless sensors in terms of design choices and associated tradeoffs. © 2013 IEEE.

  2. Justification and radiology: some ethical considerations.

    Science.gov (United States)

    Sia, Santiago

    2009-07-01

    This paper, which seeks to address the issue of justification in radiology, intends firstly to comment on the current discussion of the ethical foundation of radiological practice that focuses on the move from utilitarianism to the rights-centred criterion. Secondly, and this constitutes the bulk of the paper, it aims to offer a philosophical perspective, which is hoped will lead to a consideration of certain specific areas in ethical decision-making in the attempts here to deal with the main issue of justification in radiology.

  3. Implantable intraocular pressure monitoring systems: Design considerations

    KAUST Repository

    Arsalan, Muhammad

    2013-12-01

    Design considerations and limitations of implantable Intraocular Pressure Monitoring (IOPM) systems are presented in this paper. Detailed comparison with the state of the art is performed to highlight the benefits and challenges of the proposed design. The system-on-chip, presented here, is battery free and harvests energy from incoming RF signals. This low-cost design, in standard CMOS process, does not require any external components or bond wires to function. This paper provides useful insights to the designers of implantable wireless sensors in terms of design choices and associated tradeoffs. © 2013 IEEE.

  4. Paediatricians, social media and blogs: Ethical considerations.

    Science.gov (United States)

    St-Laurent-Gagnon, Thérèse; Coughlin, Kevin W

    2012-05-01

    The use of blogs, Facebook and similar social networking sites is rapidly expanding and, when compared with e-mail, may be having a significantly different impact on the traditional doctor-patient relationship. Characteristics specific to these online platforms have major implications for professional relationships, including the 'Facebook effect' (the relative permanence of postings) and the 'online disinhibition effect'. The present practice point illustrates relevant ethical considerations and provides guidance to paediatricians and others concerning the prudent professional and personal use of social networking media.

  5. Isolation and confinement - Considerations for colonization

    Science.gov (United States)

    Akins, F. R.

    1978-01-01

    This paper discusses three types of isolation (sensory/perceptual, temporal, and social) that could adversely affect mankind in space. The literature dealing with laboratory and field experiments relevant to these areas is summarized and suggestions are given for dealing with these problems within the space colony community. Also, consideration is given to the potential effects of physical confinement and the need for usable space. Finally, a modification of Maslow's hierarchy of needs is proposed as a theoretical framework to understand and investigate mankind's psychological needs in space.

  6. Environmental considerations for alternative fusion reactor blankets

    International Nuclear Information System (INIS)

    Johnson, A.B. Jr.; Young, J.R.

    1975-01-01

    Comparisons of alternative fusion reactor blanket/coolant systems suggest that environmental considerations will enter strongly into selection of design and materials. Liquid blankets and coolants tend to maximize transport of radioactive corrosion products. Liquid lithium interacts strongly with tritium, minimizing permeation and escape of gaseous tritium in accidents. However, liquid lithium coolants tend to create large tritium inventories and have a large fire potential compared to flibe and solid blankets. Helium coolants minimize radiation transport, but do not have ability to bind the tritium in case of accidental releases. (auth)

  7. Design considerations for a gas microcontroller

    Science.gov (United States)

    Ritter, D. A.

    1986-01-01

    Some of the design problems that are now being addressed in consideration of a microcontroller for the upcoming GAS payload are discussed. Microcontrollers will be used to run the experiments and to collect and store the data from those experiments. Some of the requirements for a microcontroller are to be small, lightweight, have low power consumption, and high reliability. Some of the solutions that were developed to meet these design requirements are discussed. At present, the experiment is still in the design stage and the final design may change from what is presented here. The search for new integrated circuits which will do all that is needed all in one package continues.

  8. CONSIDERATIONS FOR REPORTING THE PERFORMANCE OF THE SOCIALLY RESPONSIBLE COMPANIES

    Directory of Open Access Journals (Sweden)

    Violeta Isai

    2015-05-01

    Full Text Available Over time, accounting evolved from grounding on financial reports based on economic and financial performance, to the highlighting of issues based on financial, social and environmental aspects, which measures overall performance by integrating financial, social and environmental performance. In this context, economic entities should show interest and consideration in social and environmental issues in order to ensure sustainable development in accordance with the requirements of the EU framework. Corporate social responsibility is an important premise of business, being seen as a source of competitive advantage and a strategic approach to all organizations with economic potential.

  9. Aetiological considerations of acquired aplastic anaemia

    International Nuclear Information System (INIS)

    Malik, S.; Sarwar, I.; Mehmood, T.; Naz, F.

    2009-01-01

    Acquired aplastic anaemia is one of the important causes of pancytopenia. This study was conducted to observe the mode of presentation of acquired aplastic anaemia and to find out its possible etiological factors. Methods: It is a hospital based descriptive study of 100 patients of acquired aplastic anaemia. Results: Out of 100 patients 60 were male and 40 female. Majority (44%) of the patients were between 12 - 20 years of age. Patient presented with variable symptoms majority (40%) with fever. Most of the patients had haemoglobin levels between 4 - 6 gm/dl. (53%). Seventy percent of the cases had no obvious cause, while in 30% some known causative factors were found. Chloramphenicol was found to be the most common causative drug. Mortality was 35%. Thirty patients were partially treated and 15 were lost to follow up. Twenty patients showed improvement with treatment. Conclusions: Acquired aplastic anaemia is common among males and more prevalent in younger age group. It is idiopathic in 70% cases while 30% had some cause. It has very high mortality. Doctors need to keep in mind this fatal condition in patients presenting with anaemia and should properly investigate before prescribing antibiotics and haematinics. (author)

  10. Nasal encephalocele: endoscopic excision with anesthetic consideration.

    Science.gov (United States)

    Abdel-Aziz, Mosaad; El-Bosraty, Hussam; Qotb, Mohamed; El-Hamamsy, Mostafa; El-Sonbaty, Mohamed; Abdel-Badie, Hazem; Zynabdeen, Mustapha

    2010-08-01

    Nasal encephalocele may presents as a nasal mass, its treatment is surgical and it should be done early in life. When removal is indicated, there are multiple surgical approaches; including lateral rhinotomy, a transnasal approach and a coronal flap approach. However, the treatment of a basal intranasal encephalocele using transnasal endoscopic approach could obviates the possible morbidity associated with other approaches. The aim of this study was to evaluate the efficacy of endoscopic removal of intranasal encephalocele, also to document the role of anesthetist in the operative and postoperative periods. Nine cases with nasal encephalocele were included in this study; CT and/or MRI were used in their examination. The lesions were removed via transnasal endoscopic approach. Preoperative evaluation, intervention and postoperative follow-up were presented with discussion of anesthesia used for those children. The lesions of all patients were removed successfully with no recurrence through the follow-up period of at least 21 months. No cases showed morbidity or mortality intra- or post-operatively. Endoscopic excision of intranasal encephalocele is an effective method with high success rate. Anesthetist plays an important role in the operative and postoperative period, even during the endoscopic follow up; sedation of the children is usually needed. Copyright (c) 2010 Elsevier Ireland Ltd. All rights reserved.

  11. 47 CFR 76.54 - Significantly viewed signals; method to be followed for special showings.

    Science.gov (United States)

    2010-10-01

    ... located, in whole or in part, and on all other system community units, franchisees, and franchise.... 339(d). (j) Notwithstanding the requirements of this section, the signal of a television broadcast...

  12. An expanded evaluation of protein function prediction methods shows an improvement in accuracy

    NARCIS (Netherlands)

    Jiang, Yuxiang; Oron, Tal Ronnen; Clark, Wyatt T.; Bankapur, Asma R.; Andrea, D' Daniel; Lepore, Rosalba; Funk, Christopher S.; Kahanda, Indika; Verspoor, Karin M.; Ben-Hur, Asa; Koo, Da Chen Emily; Penfold-Brown, Duncan; Shasha, Dennis; Youngs, Noah; Bonneau, Richard; Lin, Alexandra; Sahraeian, Sayed M.E.; Martelli, Pier Luigi; Profiti, Giuseppe; Casadio, Rita; Cao, Renzhi; Zhong, Zhaolong; Cheng, Jianlin; Altenhoff, Adrian; Skunca, Nives; Dessimoz, Christophe; Dogan, Tunca; Hakala, Kai; Kaewphan, Suwisa; Mehryary, Farrokh; Salakoski, Tapio; Ginter, Filip; Fang, Hai; Smithers, Ben; Oates, Matt; Gough, Julian; Törönen, Petri; Koskinen, Patrik; Holm, Liisa; Chen, Ching Tai; Hsu, Wen Lian; Bryson, Kevin; Cozzetto, Domenico; Minneci, Federico; Jones, David T.; Chapman, Samuel; BKC, Dukka; Khan, Ishita K.; Kihara, Daisuke; Ofer, Dan; Rappoport, Nadav; Stern, Amos; Cibrian-Uhalte, Elena; Denny, Paul; Foulger, Rebecca E.; Hieta, Reija; Legge, Duncan; Lovering, Ruth C.; Magrane, Michele; Melidoni, Anna N.; Mutowo-Meullenet, Prudence; Pichler, Klemens; Shypitsyna, Aleksandra; Li, Biao; Zakeri, Pooya; ElShal, Sarah; Tranchevent, Léon Charles; Das, Sayoni; Dawson, Natalie L.; Lee, David; Lees, Jonathan G.; Sillitoe, Ian; Bhat, Prajwal; Nepusz, Tamás; Romero, Alfonso E.; Sasidharan, Rajkumar; Yang, Haixuan; Paccanaro, Alberto; Gillis, Jesse; Sedeño-Cortés, Adriana E.; Pavlidis, Paul; Feng, Shou; Cejuela, Juan M.; Goldberg, Tatyana; Hamp, Tobias; Richter, Lothar; Salamov, Asaf; Gabaldon, Toni; Marcet-Houben, Marina; Supek, Fran; Gong, Qingtian; Ning, Wei; Zhou, Yuanpeng; Tian, Weidong; Falda, Marco; Fontana, Paolo; Lavezzo, Enrico; Toppo, Stefano; Ferrari, Carlo; Giollo, Manuel; Piovesan, Damiano; Tosatto, Silvio C.E.; Pozo, del Angela; Fernández, José M.; Maietta, Paolo; Valencia, Alfonso; Tress, Michael L.; Benso, Alfredo; Carlo, Di Stefano; Politano, Gianfranco; Savino, Alessandro; Rehman, Hafeez Ur; Re, Matteo; Mesiti, Marco; Valentini, Giorgio; Bargsten, Joachim W.; Dijk, van Aalt-Jan; Gemovic, Branislava; Glisic, Sanja; Perovic, Vladmir; Veljkovic, Veljko; Veljkovic, Nevena; Almeida-e-Silva, Danillo C.; Vencio, Ricardo Z.N.; Sharan, Malvika; Vogel, Jörg; Kansakar, Lakesh; Zhang, Shanshan; Vucetic, Slobodan; Wang, Zheng; Sternberg, Michael J.E.; Wass, Mark N.; Huntley, Rachael P.; Martin, Maria J.; O'Donovan, Claire; Robinson, Peter N.; Moreau, Yves; Tramontano, Anna; Babbitt, Patricia C.; Brenner, Steven E.; Linial, Michal; Orengo, Christine A.; Rost, Burkhard; Greene, Casey S.; Mooney, Sean D.; Friedberg, Iddo; Radivojac, Predrag

    2016-01-01

    Background: A major bottleneck in our understanding of the molecular underpinnings of life is the assignment of function to proteins. While molecular experiments provide the most reliable annotation of proteins, their relatively low throughput and restricted purview have led to an increasing role

  13. Literature Shows Recurring Efforts at Finding a Method of Teaching Ethics.

    Science.gov (United States)

    Knudtson, Judy

    1994-01-01

    Reviews classroom journalism texts and articles published in "Quill and Scroll" and this journal since the early 1970s. Notes that the topic of ethics has been addressed recurrently. Finds a wealth of commitment to and concern for ethical issues for high school journalists. (RS)

  14. Improved meta-analytic methods show no effect of chromium supplements on fasting glucose.

    Science.gov (United States)

    Bailey, Christopher H

    2014-01-01

    The trace mineral chromium has been extensively researched over the years in its role in glucose metabolism. Dietary supplement companies have attempted to make claims that chromium may be able to treat or prevent diabetes. Previous meta-analyses/systematic reviews have indicated that chromium supplementation results in a significant lowering of fasting glucose in diabetics but not in nondiabetics. A meta-analysis was conducted using an alternative measure of effect size, d(ppc2) in order to account for changes in the control group as well as the chromium group. The literature search included MEDLINE, the Cochrane Controlled Trials Register, and previously published article reviews, systematic reviews, and meta-analyses. Included studies were randomized, placebo-controlled trials in the English language with subjects that were nonpregnant adults, both with and without diabetes. Sixteen studies with 809 participants (440 diabetics and 369 nondiabetics) were included in the analysis. Screening for publication bias indicated symmetry of the data. Tests of heterogeneity indicated the use of a fixed-effect model (I² = 0 %). The analysis indicated that there was no significant effect of chromium supplementation in diabetics or nondiabetics, with a weighted average effect size of 0.02 (SE = 0.07), p = 0.787, CI 95 % = -0.12 to 0.16. Chromium supplementation appears to provide no benefits to populations where chromium deficiency is unlikely.

  15. Consideration of beam plasma ion-source

    International Nuclear Information System (INIS)

    Sano, Fumimichi; Kusano, Norimasa; Ishida, Yoshihiro; Ishikawa, Junzo; Takagi, Toshinori

    1976-01-01

    Theoretical and experimental analyses and their comparison were made on the plasma generation and on the beam extraction for the beam plasma ion-source. The operational principle and the structure of the ion-source are explained in the first part. Considerations are given on the electron beam-plasma interaction and the resulting generation of high frequency or microwaves which in turn increases the plasma density. The flow of energy in this system is also explained in the second part. The relation between plasma density and the imaginary part of frequency is given by taking the magnetic flux density, the electron beam energy, and the electron beam current as parameters. The relations between the potential difference between collector and drift tube and the plasma density or the ion-current are also given. Considerations are also given to the change of the plasma density due to the change of the magnetic flux density at drift tube, the change of the electron beam energy, and the change of the electron beam current. The third part deals with the extraction characteristics of the ion beam. The structure of the multiple-aperture electrode and the relation between plasma density and the extracted ion current are explained. (Aoki, K.)

  16. Structural considerations in steam generator replacement

    International Nuclear Information System (INIS)

    Bertheau, S.R.; Gazda, P.A.

    1991-01-01

    Corrosion of the tubes and tube-support structures inside pressurized water reactor (PWR) steam generators has led many utilities to consider a replacement of the generators. Such a project is a major undertaking for a utility and must be well planned to ensure an efficient and cost-effective effort. This paper discusses various structural aspects of replacement options, such as total or partial generator replacement, along with their associated pipe cuts; major structural aspects associated with removal paths through the equipment hatch or through an opening in the containment wall, along with the related removal processes; onsite movement and storage of the generators; and the advantages and disadvantages of the removal alternatives. This paper addresses the major structural considerations associated with a steam generator replacement project. Other important considerations (e.g., licensing, radiological concerns, electrical requirements, facilities for management and onsite administrative activities, storage and fabrication activities, and offsite transportation) are not discussed in this paper, but should be carefully considered when undertaking a replacement project

  17. Exercise and Early-Onset Alzheimer’s Disease: Theoretical Considerations

    Directory of Open Access Journals (Sweden)

    Astrid M. Hooghiemstra

    2012-04-01

    Full Text Available Background/Aims: Although studies show a negative relationship between physical activity and the risk for cognitive impairment and late-onset Alzheimer’s disease, studies concerning early-onset Alzheimer’s disease (EOAD are lacking. This review aims to justify the value of exercise interventions in EOAD by providing theoretical considerations that include neurobiological processes. Methods: A literature search on key words related to early-onset dementia, exercise, imaging, neurobiological mechanisms, and cognitive reserve was performed. Results/Conclusion: Brain regions and neurobiological processes contributing to the positive effects of exercise are affected in EOAD and, thus, provide theoretical support for exercise interventions in EOAD. Finally, we present the design of a randomized controlled trial currently being conducted in early-onset dementia patients.

  18. Analogy in causal inference: rethinking Austin Bradford Hill's neglected consideration.

    Science.gov (United States)

    Weed, Douglas L

    2018-05-01

    The purpose of this article was to rethink and resurrect Austin Bradford Hill's "criterion" of analogy as an important consideration in causal inference. In epidemiology today, analogy is either completely ignored (e.g., in many textbooks), or equated with biologic plausibility or coherence, or aligned with the scientist's imagination. None of these examples, however, captures Hill's description of analogy. His words suggest that there may be something gained by contrasting two bodies of evidence, one from an established causal relationship, the other not. Coupled with developments in the methods of systematic assessments of evidence-including but not limited to meta-analysis-analogy can be restructured as a key component in causal inference. This new approach will require that a collection-a library-of known cases of causal inference (i.e., bodies of evidence involving established causal relationships) be developed. This library would likely include causal assessments by organizations such as the International Agency for Research on Cancer, the National Toxicology Program, and the United States Environmental Protection Agency. In addition, a process for describing key features of a causal relationship would need to be developed along with what will be considered paradigm cases of causation. Finally, it will be important to develop ways to objectively compare a "new" body of evidence with the relevant paradigm case of causation. Analogy, along with all other existing methods and causal considerations, may improve our ability to identify causal relationships. Copyright © 2018 Elsevier Inc. All rights reserved.

  19. Robustness Assessment of Urban Road Network with Consideration of Multiple Hazard Events.

    Science.gov (United States)

    Zhou, Yaoming; Sheu, Jiuh-Biing; Wang, Junwei

    2017-08-01

    Robustness measures a system's ability of being insensitive to disturbances. Previous studies assessed the robustness of transportation networks to a single disturbance without considering simultaneously happening multiple events. The purpose of this article is to address this problem and propose a new framework to assess the robustness of an urban transportation network. The framework consists of two layers. The upper layer is to define the robustness index based on the impact evaluation in different scenarios obtained from the lower layer, whereas the lower layer is to evaluate the performance of each hypothetical disrupted road network given by the upper layer. The upper layer has two varieties, that is, robustness against random failure and robustness against intentional attacks. This robustness measurement framework is validated by application to a real-world urban road network in Hong Kong. The results show that the robustness of a transport network with consideration of multiple events is quite different from and more comprehensive than that with consideration of only a single disruption. We also propose a Monte Carlo method and a heuristic algorithm to handle different scenarios with multiple hazard events, which is proved to be quite efficient. This methodology can also be applied to conduct risk analysis of other systems where multiple failures or disruptions exist. © 2017 Society for Risk Analysis.

  20. Innovative nuclear power plant building arragement in consideration of decommissioning

    International Nuclear Information System (INIS)

    Choi, Won Jun; Roh, Myung Sub; Kim, Chang Lak

    2017-01-01

    A new concept termed the Innovative Nuclear Power Plant Building Arrangement (INBA) strategy is a new nuclear power plant building arrangement method which encompasses upfront consideration of more efficient decommissioning. Although existing decommissioning strategies such as immediate dismantling and differed dismantling has the advantage of either early site restoration or radioactive decommissioning waste reduction, the INBA strategy has the advantages of both strategies. In this research paper, the concept and the implementation method of the INBA strategy will be described. Two primary benefits will be further described: (1) early site restoration; and (2) radioactive waste reduction. Several other potential benefits will also be identified. For the estimation of economic benefit, the INBA strategy, with two primary benefits, will be compared with the immediate dismantling strategy. The effect of a short life cycle nuclear power plant in combination with the INBA strategy will be reviewed. Finally, some of the major impediments to the realization of this strategy will be discussed

  1. Design consideration of resonance inverters with electro-technological application

    Science.gov (United States)

    Hinov, Nikolay

    2017-12-01

    This study presents design consideration of resonance inverters with electro-technological application. The presented methodology was achieved as a result of investigations and analyses of different types and working regimes of resonance inverters, made by the author. Are considered schemes of resonant inverters without inverse diodes. The first harmonic method is used in the analysis and design. This method for the case of inverters with electro-technological application gives very good accuracy. This does not require the use of a complex and heavy mathematical apparatus. The proposed methodology is easy to use and is suitable for use in training students in power electronics. Authenticity of achieved results is confirmed by simulating and physical prototypes research work.

  2. Salt creep design consideration for underground nuclear waste storage

    International Nuclear Information System (INIS)

    Li, W.T.; Wu, C.L.; Antonas, N.J.

    1983-01-01

    This paper summarizes the creep consideration in the design of nuclear waste storage facilities in salt, describes the non-linear analysis method for evaluating the design adequacy, and presents computational results for the current storage design. The application of rock mechanics instrumentation to assure the appropriateness of the design is discussed. It also describes the design evolution of such a facility, starting from the conceptual design, through the preliminary design, to the detailed design stage. The empirical design method, laboratory tests and numerical analyses, and the underground in situ tests have been incorporated in the design process to assure the stability of the underground openings, retrievability of waste during the operation phase and encapsulation of waste after decommissioning

  3. Environmental and regulatory considerations when planning a geophysical program

    International Nuclear Information System (INIS)

    Down-Cicoria, C.

    1999-01-01

    Public concerns regarding the environmental impact of geophysical programs have resulted in more pressure on the federal and provincial governments to regulate and protect unique ecosites. In the past decade, about 1 million kilometres of seismic have been shot by the petroleum industry in Alberta alone, representing about 70,000 hectares of land base. This paper reviewed how a preliminary assessment of any geophysical project should consider the effects of all projects on the terrain, climate, vegetation, soils, fisheries, wildlife, aquatic ecosystems, heritage resources, and timber dispositions. Geo-administrative boundaries, field assessments, environmental assessments and mitigation measures such as low impact line cutting methods, timing methods, and heli-portable operations must also be considered. Special considerations when planning a three-dimensional program were highlighted. Certain equipment suitable as mitigation measures such as mulchers, hydro-axes, enviro-drills, biodegradable lathes, tracked/low PSI equipment, and doglegs were also reviewed. 15 refs., 2 tabs., 18 figs

  4. Innovative nuclear power plant building arragement in consideration of decommissioning

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Won Jun; Roh, Myung Sub; Kim, Chang Lak [Dept. of Nuclear Power Plant Engineering, KEPCO International Nuclear Graduate School, Ulsan (Korea, Republic of)

    2017-04-15

    A new concept termed the Innovative Nuclear Power Plant Building Arrangement (INBA) strategy is a new nuclear power plant building arrangement method which encompasses upfront consideration of more efficient decommissioning. Although existing decommissioning strategies such as immediate dismantling and differed dismantling has the advantage of either early site restoration or radioactive decommissioning waste reduction, the INBA strategy has the advantages of both strategies. In this research paper, the concept and the implementation method of the INBA strategy will be described. Two primary benefits will be further described: (1) early site restoration; and (2) radioactive waste reduction. Several other potential benefits will also be identified. For the estimation of economic benefit, the INBA strategy, with two primary benefits, will be compared with the immediate dismantling strategy. The effect of a short life cycle nuclear power plant in combination with the INBA strategy will be reviewed. Finally, some of the major impediments to the realization of this strategy will be discussed.

  5. Innovative Nuclear Power Plant Building Arrangement in Consideration of Decommissioning

    Directory of Open Access Journals (Sweden)

    Won-Jun Choi

    2017-04-01

    Full Text Available A new concept termed the Innovative Nuclear Power Plant Building Arrangement (INBA strategy is a new nuclear power plant building arrangement method which encompasses upfront consideration of more efficient decommissioning. Although existing decommissioning strategies such as immediate dismantling and differed dismantling has the advantage of either early site restoration or radioactive decommissioning waste reduction, the INBA strategy has the advantages of both strategies. In this research paper, the concept and the implementation method of the INBA strategy will be described. Two primary benefits will be further described: (1 early site restoration; and (2 radioactive waste reduction. Several other potential benefits will also be identified. For the estimation of economic benefit, the INBA strategy, with two primary benefits, will be compared with the immediate dismantling strategy. The effect of a short life cycle nuclear power plant in combination with the INBA strategy will be reviewed. Finally, some of the major impediments to the realization of this strategy will be discussed.

  6. Intracerebral metastasis showing restricted diffusion: Correlation with histopathologic findings

    Energy Technology Data Exchange (ETDEWEB)

    Duygulu, G. [Radiology Department, Ege University Medicine School, Izmir (Turkey); Ovali, G. Yilmaz [Radiology Department, Celal Bayar University Medicine School, Manisa (Turkey)], E-mail: gulgun.yilmaz@bayar.edu.tr; Calli, C.; Kitis, O.; Yuenten, N. [Radiology Department, Ege University Medicine School, Izmir (Turkey); Akalin, T. [Pathology Department, Ege University Medicine School, Izmir (Turkey); Islekel, S. [Neurosurgery Department, Ege University Medicine School, Izmir (Turkey)

    2010-04-15

    Objective: We aimed to detect the frequency of restricted diffusion in intracerebral metastases and to find whether there is correlation between the primary tumor pathology and diffusion-weighted MR imaging (DWI) findings of these metastases. Material and methods: 87 patients with intracerebral metastases were examined with routine MR imaging and DWI. 11 hemorrhagic metastatic lesions were excluded. The routine MR imaging included three plans before and after contrast enhancement. The DWI was performed with spin-echo EPI sequence with three b values (0, 500 and 1000), and ADC maps were calculated. 76 patients with metastases were grouped according to primary tumor histology and the ratios of restricted diffusion were calculated according to these groups. ADCmin values were measured within the solid components of the tumors and the ratio of metastases with restricted diffusion to that which do not show restricted diffusion were calculated. Fisher's exact and Mann-Whitney U tests were used for the statistical analysis. Results: Restricted diffusion was observed in a total of 15 metastatic lesions (19, 7%). Primary malignancy was lung carcinoma in 10 of these cases (66, 6%) (5 small cell carcinoma, 5 non-small cell carcinoma), and breast carcinoma in three cases (20%). Colon carcinoma and testicular teratocarcinoma were the other two primary tumors in which restricted diffusion in metastasis was detected. There was no statistical significant difference between the primary pathology groups which showed restricted diffusion (p > 0.05). ADCmin values of solid components of the metastasis with restricted diffusion and other metastasis without restricted diffusion also showed no significant statistical difference (0.72 {+-} 0.16 x 10{sup -3} mm{sup 2}/s and 0.78 {+-} 21 x 10{sup -3} mm{sup 2}/s respectively) (p = 0.325). Conclusion: Detection of restricted diffusion on DWI in intracerebral metastasis is not rare, particularly if the primary tumor is lung or breast

  7. Considerations about mediative in initial petition

    Directory of Open Access Journals (Sweden)

    Maria das Vitórias Nunes Silva Lourenço

    2013-12-01

    Full Text Available This paper presents considerations about Initial Petition, textual/discursive genre, which is a genre circumscribed in the judicial domain with relation to the Commitment. For this purpose, this article exposes the text plan of the Initial Petition from the postulations of Adam (2011. In the same way, it studies the mediative frameworks based on Guentchéva (1994, 1996, which develop the notion of mediative grammatical categories, that permits the linguistic marking of distance and engagement of the enunciator with regard to the information expressed. It evidences the relevance of the use of mediated constructions in the judicial text, as they function as attenuated strategies to the responsibility of the producer of the text with what is said, and at the same time points to a discourse of authority through the entrance of the sources of law.

  8. Design considerations for ITER toroidal field coils

    International Nuclear Information System (INIS)

    Kalsi, S.S.; Lousteau, D.C.; Miller, J.R.

    1987-01-01

    The International Thermonuclear Experimental Reactor (ITER) is a new tokamak design project with joint participation from Europe, Japan, the Union of Soviet Socialist Republics (U.S.S.R.), and the United States. This paper describes a magnetic and mechanical design methodology for toroidal field (TF) coils that employs Nb 3 Sn superconductor technology. Coil winding is sized by using conductor concepts developed for the U.S. TIBER concept. Manifold concepts are presented for the complete cooling system. Also included are concepts for the coil structural arrangement. The effects of in-plane and out-of-plane loads are included in the design considerations for the windings and case. Concepts are presented for reacting these loads with a minimum amount of additional structural material. Concepts discussed in this paper could be considered for the ITER TF coils

  9. Materials Lifecycle and Environmental Consideration at NASA

    Science.gov (United States)

    Clark-Ingram, Marceia

    2010-01-01

    The aerospace community faces tremendous challenges with continued availability of existing material supply chains during the lifecycle of a program. Many obsolescence drivers affect the availability of materials: environmental safety ahd health regulations, vendor and supply economics, market sector demands,and natural disasters. Materials selection has become increasingly more critical when designing aerospace hardware. NASA and DoD conducted a workshop with subject matter experts to discuss issues and define solutions for materials selections during the lifecycle phases of a product/system/component. The three primary lifecycle phases were: Conceptualization/Design, Production & Sustainment, and End of life / Reclamation. Materials obsolescence and pollution prevention considerations were explored for the aforementioned lifecycle phases. The recommended solutions from the workshop are being presented.

  10. Economic and care considerations of Marfan syndrome.

    Science.gov (United States)

    Blankart, Carl Rudolf; Milstein, Ricarda; Rybczynski, Meike; Schüler, Helke; von Kodolitsch, Yskert

    2016-10-01

    Marfan syndrome is a rare multisystem disease of the connective tissue, which affects multiple organ systems. advances in healthcare have doubled the life-expectancy of patients over the past three decades. to date, there is no comprehensive review that consolidates economic considerations and care for marfan patients. Areas covered: Present research suggests that there may be a link between treatment pattern, disease progression and economic costs of Marfan syndrome. It indicates that an early detection of the disease and preventive interventions achieve a dual aim. From a patient perspective, it may reduce the amount of emergency surgery or intervention, and inpatient stays. In addition, it slows disease progression, lowers lifestyle restrictions, reduces psychological stress, and improves health-related quality of life. Expert commentary: Early detection and preventive measures are likely to achieve a dual aim by simultaneously containing costs and reducing the number and length of inpatient stays.

  11. Opening up education - some pedagogical considerations

    DEFF Research Database (Denmark)

    Bang, Jørgen; Dalsgaard, Christian; Kjær, Arne

    2016-01-01

    would we need universities? Libraries could do the job!” In order to open up education, we need to develop a pedagogical framework for knowledge building to supplement the tradition for knowledge acquisition in higher education. In this article we present our strategic considerations for organising......In the “Communication from the Commission to the European Parliament, the Council, the European Economic and Social Committee and the Committee of the Regions” from September 25, 2013 the Commission advocated strongly to ‘Opening up Education’ through ‘Innovative teaching and learning for all...... through new Technologies and Open Educational Resources’. We strongly support this vision for the future and aim at realising it within a Danish context with a population of five million. However, we also retain a certain scepticism and remember the saying of David Wiley: “If content is all we need, why...

  12. Smallpox: clinical highlights and considerations for vaccination.

    Directory of Open Access Journals (Sweden)

    Mahoney M

    2003-01-01

    Full Text Available Smallpox virus has gained considerable attention as a potential bioterrorism agent. Recommendations for smallpox (vaccinia vaccination presume a low risk for use of smallpox as a terrorist biological agent and vaccination is currently recommended for selected groups of individuals such as health care workers, public health authorities, and emergency/rescue workers, among others. Information about adverse reactions to the smallpox vaccine is based upon studies completed during the 1950s and 1960s. The prevalence of various diseases has changed over the last four decades and new disease entities have been described during this period. The smallpox vaccination may be contra-indicated in many of these conditions. This has made pre-screening of potential vaccines necessary. It is believed that at present, the risks of vaccine-associated complications far outweigh the potential benefits of vaccination in the general population.

  13. Current Considerations About the Elderly and Firearms

    Science.gov (United States)

    Mertens, Brian

    2012-01-01

    In the United States, more than 17 million people aged 65 years or older own a firearm. They have the highest rate of suicide by a firearm, and recent data suggest that a disproportionate number apply to carry a concealed weapon. At least one new handgun has been designed and marketed for older people. Memory, thinking, and judgment as well as physical and behavioral competence issues related to an elderly person's safe operation of a motor vehicle apply to firearms, too. Gun availability can pose a particular risk to those with dementia and to their caretakers. The elderly constitute a substantial and rapidly growing population and market segment for whom the public health implications of firearm production, promotion, access, ownership, and use merit consideration. PMID:22390501

  14. Magnet design considerations for Tokamak fusion reactors

    International Nuclear Information System (INIS)

    Purcell, J.R.; Chen, W.; Thomas, R.

    1976-01-01

    Design problems for superconducting ohmic heating and toroidal field coils for large Tokamak fusion reactors are discussed. The necessity for making these coils superconducting is explained, together with the functions of these coils in a Tokamak reactor. Major problem areas include materials related aspects and mechanical design and cryogenic considerations. Projections and comparisons are made based on existing superconducting magnet technology. The mechanical design of large-scale coils, which can contain the severe electromagnetic loading and stress generated in the winding, are emphasized. Additional major tasks include the development of high current conductors for pulsed applications to be used in fabricating the ohmic heating coils. It is important to note, however, that no insurmountable technical barriers are expected in the course of developing superconducting coils for Tokamak fusion reactors. (Auth.)

  15. Psychosocial considerations about children and radiological events

    International Nuclear Information System (INIS)

    Lemyre, L.; Corneil, W.; Johnson, C.; Boutette, P.

    2010-01-01

    Children are identified as a vulnerable population in the case of radiological events because of their increased physical sensitivity to radiation and its impact on critical development stages. Using a comprehensive integrated risk framework, psychosocial risk protective factors are discussed in a social ecology paradigm. Children have been shown to be both vulnerable and resilient; they are both easily impressionable and also quick to adapt and learn. Psychosocial interventions during, after and most efficiently before an event can improve outcome, especially if they involve parents and schools, media and work organisations. Public education through children should be encouraged to increase knowledge of radiation and strategies to minimise exposure and irradiation. Children can become vectors of prevention, preparedness and mitigation through information and behavioural rehearsal. Special consideration must therefore be given to education, school programmes, practice rehearsal and media exposure. (authors)

  16. Senior academic physicians and retirement considerations.

    Science.gov (United States)

    Moss, Arthur J; Greenberg, Henry; Dwyer, Edward M; Klein, Helmut; Ryan, Daniel; Francis, Charles; Marcus, Frank; Eberly, Shirley; Benhorin, Jesaia; Bodenheimer, Monty; Brown, Mary; Case, Robert; Gillespie, John; Goldstein, Robert; Haigney, Mark; Krone, Ronald; Lichstein, Edgar; Locati, Emanuela; Oakes, David; Thomsen, Poul Erik Bloch; Zareba, Wojciech

    2013-01-01

    An increasing number of academic senior physicians are approaching their potential retirement in good health with accumulated clinical and research experience that can be a valuable asset to an academic institution. Considering the need to let the next generation ascend to leadership roles, when and how should a medical career be brought to a close? We explore the roles for academic medical faculty as they move into their senior years and approach various retirement options. The individual and institutional considerations require a frank dialogue among the interested parties to optimize the benefits while minimizing the risks for both. In the United States there is no fixed age for retirement as there is in Europe, but European physicians are initiating changes. What is certain is that careful planning, innovative thinking, and the incorporation of new patterns of medical practice are all part of this complex transition and timing of senior academic physicians into retirement. Copyright © 2013 Elsevier Inc. All rights reserved.

  17. Practical design considerations for photovoltaic power station

    Science.gov (United States)

    Swanson, T. D.

    Aspects of photovoltaic (PV) technology are discussed along with generic PV design considerations, taking into account the resource sunlight, PV modules and their reliability, questions of PV system design, the support structure subsystem, and a power conditioning unit subsystem. A description is presented of two recent projects which demonstrate the translation of an idea into actual working PV systems. A privately financed project in Denton, Maryland, went on line in early December, 1982, and began providing power to the local utility grid. It represents the first intermediate size, grid-connected, privately financed power station in the U.S. Based on firm quotes, the actual cost of this system is about $13/W peak. The other project, called the PV Breeder, is an energy independent facility which utilizes solar power to make new solar cells. It is also the first large industrial structure completely powered by the sun.

  18. Liquid Hydrogen Sensor Considerations for Space Exploration

    Science.gov (United States)

    Moran, Matthew E.

    2006-01-01

    The on-orbit management of liquid hydrogen planned for the return to the moon will introduce new considerations not encountered in previous missions. This paper identifies critical liquid hydrogen sensing needs from the perspective of reliable on-orbit cryogenic fluid management, and contrasts the fundamental differences in fluid and thermodynamic behavior for ground-based versus on-orbit conditions. Opportunities for advanced sensor development and implementation are explored in the context of critical Exploration Architecture operations such as on-orbit storage, docking, and trans-lunar injection burn. Key sensing needs relative to these operations are also examined, including: liquid/vapor detection, thermodynamic condition monitoring, mass gauging, and leak detection. Finally, operational aspects of an integrated system health management approach are discussed to highlight the potential impact on mission success.

  19. Design considerations for prepress color proof measurement

    Science.gov (United States)

    Spooner, David L.

    1993-06-01

    For our purposes, we needed colorimetric measurements or, better yet, spectral reflectance data. Our survey of commercially available instruments identified one spectrocolorimeter, the Hunter PICS (manufactured by Hunter Associates Laboratory, Inc.), which could be programmed to automatically measure the color (and spectral reflectance) of large numbers of samples on a proof sheet. After an evaluation of this instrument, which included measuring over 10,000 exhibits, it was decided that the unit did not fully meet our needs. This resulted in a decision to integrate another instrument, the Byk-Gardner Color Machine (manufactured by Byk-Gardner, Inc.), with an x-y positioning mechanism. This paper describes the design considerations used in the development of our color measurement system.

  20. Nuclear energy: considerations about nuclear trade

    International Nuclear Information System (INIS)

    Goes Fischer, M.D. de.

    1988-01-01

    A general view of historical aspects of nuclear energy and the arrangements to assure its use for peaceful purposes are presented. Then the internal character of nuclear energy in a juride context is demonstrated; some consideration about the international organizations and conventions and the Brazilian Legislation in the nuclear area are examined. It also deals with the political aspects of nuclear trade and the function of IAEA in this are. Furthermore the restrictions imposed by Non-Proliferation Treaty-NPT, the objectures of the Tlatelolco Treaty and ''London Club'' guidelines. Afterwards the bilateral cooperation under taken by countries and its agreements are discussed. Besides some aspects of agreements made between United States, France Germany and Brazil are discussed [pt

  1. CONSIDERATIONS ON TRANSACTIONS OF FOREIGN TRADE

    Directory of Open Access Journals (Sweden)

    Paliu-Popa Lucia

    2009-05-01

    Full Text Available In the complex connection process of national economies to global economy flows, an important role has the foreign trade, which in recent decades has become, in the market economy conditions, one of the factors determining for economic growth. Foreign trade, as a separate branch of the national economy is an important factor of economic growth, caused by the internationalization of business and determining for the process of globalization. For Romania, a country still in transition and recent member of the European Union is particularly important to enhance the participation to international trade in goods and services, but also attracting foreign investments in the economy as the main possibilities for the re-industry and restructuring the national economy in order to creation and maintenance of sustainable competitive advantages. Starting from these considerations, in this article I addressed/aproached the theoretical aspects of foreign trade, without omitting intracomunity purchases and deliveries of goods.

  2. Considerations for high-brightness electron sources

    International Nuclear Information System (INIS)

    Jameson, R.A.

    1990-01-01

    Particle accelerators are now used in many areas of physics research and in industrial and medical applications. New uses are being studied to address major societal needs in energy production, materials research, generation of intense beams of radiation at optical and suboptical wavelengths, treatment of various kinds of waste, and so on. Many of these modern applications require a high intensity beam at the desired energy, along with a very good beam quality in terms of the beam confinement, aiming, or focusing. Considerations for ion and electron accelerators are often different, but there are also many commonalties, and in fact, techniques derived for one should perhaps more often be considered for the other as well. We discuss some aspects of high-brightness electron sources here from that point of view. 6 refs

  3. Systems considerations in seismic margin evaluations

    International Nuclear Information System (INIS)

    Buttermer, D.R.

    1987-01-01

    Increasing knowledge in the geoscience field has led to the understanding that, although highly unlikely, it is possible for a nuclear power plant to be subjected to earthquake ground motion greater than that for which the plant was designed. While it is recognized that there are conservatisms inherent in current design practices, interest has developed in evaluating the seismic risk of operating plants. Several plant-specific seismic probabilistic risk assessments (SPRA) have been completed to address questions related to the seismic risk of a plant. The results from such SPRAs are quite informative, but such studies may entail a considerable amount of expensive analysis of large portions of the plant. As an alternative to an SPRA, it may be more practical to select an earthquake level above the design basis for which plant survivability is to be demonstrated. The principal question to be addressed in a seismic margin evaluation is: At what ground motion levels does one have a high confidence that the probability of seismically induced core damage is sufficiently low? In a seismic margin evaluation, an earthquake level is selected (based on site-specific geoscience considerations) for which a stable, long-term safe shutdown condition is to be demonstrated. This prespecified earthquake level is commonly referred to as the seismic margin earthquake (SME). The Electric Power Research Institute is currently supporting a research project to develop procedures for use by the utilities to allow them to perform nuclear plant seismic margin evaluations. This paper describes the systems-related aspects of these procedures

  4. Orthodontic treatment considerations in Down syndrome patients

    Directory of Open Access Journals (Sweden)

    Sianiwati Goenharto

    2012-03-01

    Full Text Available Background: Down syndrome is an easily recognized congenital disease anomaly, a common autosomal chromosomal anomaly with high prevalence of malocclusion. Orthodontic treatment demand should be high but it seems difficult to be done because of specific condition of disability. Purpose: The purpose of this literature review was to discribe the orthodontic problems found in Down syndrome patients and several consideration that shoud be done to treat them. Reviews: Many studies report the high prevalence of malocclusion among people with Down syndrome. There is a greater frequency of clas III relationship, crossbite, crowding and also open bite. Several problems might appear in the treatment because of dental, medical, mental, and behavioural factor. Conclusion: It is concluded that orthodonic treatment can be performed in Down syndrome patient, although several difficulties may appear. Good consideration in mental, behavior, medical and also dental condition will influence whether the treatment will success or not. Special care and facilities will support the orthodontic treatment.Latar belakang: Sindroma Down adalah suatu kelainan congenital yang mudah dikenali, merupakan kelaian kromosom autosomal yang cukup banyak terjadi, dengan prevalensi maloklusi cukup tinggi. Seharusnya permintaan akan perawatan ortodonti juga tinggi meskipun tampaknya sulit dilakukan karena adanya kondisi ketidakmampuan/cacat yang spesifik. Tujuan: Tujuan studi pustaka ini adalah untuk menggambarkan problem perawatan ortodonti pada penderita sindroma Down dan pertimbangan apa yang sebaiknya diambil untuk mengatasi masalah tersebut. Tinjauan pustaka: Banyak penelitian melaporkan tentang prevalensi maloklusi yang tinggi pada penderita sindroma Down. Maloklusi yang sering dijumpai adalah relasi klas III, gigitan silang, berdesakan dan juga gigitan terbuka. Problem dapat terjadi saat perawatan ortodonti karena adanya faktor dental, medis, mental dan tingkah laku penderita

  5. Economic and developmental considerations for pharmacogenomic technology.

    Science.gov (United States)

    Vernon, John A; Johnson, Scott J; Hughen, W Keener; Trujillo, Antonio

    2006-01-01

    The pharmaceutical industry's core business is the innovation, development and marketing of new drugs. Pharmacogenetic (PG) testing and technology has the potential to increase a drug's value in many ways. A critical issue for the industry is whether products in development should be teamed with genetic tests that could segment the total population into responders and non-responders. In this paper we use a cost-effectiveness framework to model the strategic decision-making considerations by pharmaceutical manufacturers as they relate to drug development and the new technology of PG (the science of using genetic markers to predict drug response). In a simple, static, one-period model we consider three drug development strategies: a drug is exclusively developed and marketed to patients with a particular genetic marker; no distinguishing among patients based on the expression of a genetic marker is made (traditional approach); and a strategy whereby a drug is marketed to patients both with and without the genetic marker but there is price discrimination between the two subpopulations. We developed three main principles: revenues under a strategy targeting only the responder subpopulation will never generate more revenue than that which could have been obtained under a traditional approach; total revenues under a targeted PG strategy will be less than that under a traditional approach but higher than a naive [corrected] view would believe them to be; and a traditional [corrected] approach will earn the same total revenues as a price discrimination strategy, assuming no intermarket arbitrage. While these principles relate to the singular (and quite narrow) consideration of drug revenues, they may nevertheless partially explain why PG is not being used as widely as was predicted several years ago when the technology first became available, especially in terms of pharmaceutical manufacturer-developed tests.

  6. Synthetic vision systems: operational considerations simulation experiment

    Science.gov (United States)

    Kramer, Lynda J.; Williams, Steven P.; Bailey, Randall E.; Glaab, Louis J.

    2007-04-01

    Synthetic vision is a computer-generated image of the external scene topography that is generated from aircraft attitude, high-precision navigation information, and data of the terrain, obstacles, cultural features, and other required flight information. A synthetic vision system (SVS) enhances this basic functionality with real-time integrity to ensure the validity of the databases, perform obstacle detection and independent navigation accuracy verification, and provide traffic surveillance. Over the last five years, NASA and its industry partners have developed and deployed SVS technologies for commercial, business, and general aviation aircraft which have been shown to provide significant improvements in terrain awareness and reductions in the potential for Controlled-Flight-Into-Terrain incidents / accidents compared to current generation cockpit technologies. It has been hypothesized that SVS displays can greatly improve the safety and operational flexibility of flight in Instrument Meteorological Conditions (IMC) to a level comparable to clear-day Visual Meteorological Conditions (VMC), regardless of actual weather conditions or time of day. An experiment was conducted to evaluate SVS and SVS-related technologies as well as the influence of where the information is provided to the pilot (e.g., on a Head-Up or Head-Down Display) for consideration in defining landing minima based upon aircraft and airport equipage. The "operational considerations" evaluated under this effort included reduced visibility, decision altitudes, and airport equipage requirements, such as approach lighting systems, for SVS-equipped aircraft. Subjective results from the present study suggest that synthetic vision imagery on both head-up and head-down displays may offer benefits in situation awareness; workload; and approach and landing performance in the visibility levels, approach lighting systems, and decision altitudes tested.

  7. Compulsion in family planning: the fundamental considerations.

    Science.gov (United States)

    Pethe, V P

    1979-03-01

    Focus is on some of the basic issues and considerations involved in the question of compulsion in family planning, which in terms of current contraceptive technology, only means compulsory sterilization. Pressures have been increasing to implement more stringent measures to control population growth in most of the developing countries throughout the world. During the Emergency in India (1975-1977) the government at that time, along with some individuals and groups, deemed it necessary to adopt the drastic measure of compulsory sterilization. The six sections of the discussion deal with the following: 1) compulsory family planning as rational or ethical choice basic issues; 2) neo-Malthusian thesis on compulsion - fallacies, dangers and inadequacies; 3) ethical and philosophical problems - premise of irresponsible procreation; 4) individual rights versus societal interests; 5) elitism in social policy and cost benefit considerations; and 6) international consensus against compulsion. All forums, under the auspices of the United Nations, of which India is a member, have rejected coercion and reiterated repeatedly that every individual has a basic human right to decide how many children to have and at what intervals. The most recent forum to endorse the human right to family size was the World Population Conference held at Bucharest in 1974. The 14 conditions spelled out by the United Nations Fund for Population Activity for effecting a free and responsible choice in family size may form a sound basis for a comprehensive policy concerning family planning in India. The coercive measures adopted during the Emergency are responsible for a backlash in India and retarding the progress of the family planning movement.

  8. Considerations on the DEMO pellet fuelling system

    Energy Technology Data Exchange (ETDEWEB)

    Lang, P.T., E-mail: peter.lang@ipp.mpg.de [Max-Planck-Institut für Plasmaphysik, Boltzmannstr. 2, 85748 Garching (Germany); Day, Ch. [Karlsruhe Institute of Technology, 76021 Karlsruhe (Germany); Fable, E. [Max-Planck-Institut für Plasmaphysik, Boltzmannstr. 2, 85748 Garching (Germany); Igitkhanov, Y. [Karlsruhe Institute of Technology, 76021 Karlsruhe (Germany); Köchl, F. [Association EURATOM-Ö AW/ATI, Atominstitut, TU Wien, 1020 Vienna (Austria); Mooney, R. [Culham Centre for Fusion Energy, Culham Science Centre, Oxfordshire OX14 3DB (United Kingdom); Pegourie, B. [CEA, IRFM, 13108 Saint-Paul-lez-Durance (France); Ploeckl, B. [Max-Planck-Institut für Plasmaphysik, Boltzmannstr. 2, 85748 Garching (Germany); Wenninger, R. [Max-Planck-Institut für Plasmaphysik, Boltzmannstr. 2, 85748 Garching (Germany); EFDA, Garching (Germany); Zohm, H. [Max-Planck-Institut für Plasmaphysik, Boltzmannstr. 2, 85748 Garching (Germany)

    2015-10-15

    Graphical abstract: - Highlights: • Considerations are made for a core particle fuelling system covering all DEMO requirements. • Particle deposition beyond the pedestal top is needed to achieve efficient fuelling. • Conventional pellet technology enabling launching from the torus inboard side can be used. • Efforts have been taken for integrating a suitable pellet guiding system into the EU DEMO model. • In addition, further techniques bearing potential for advanced fuelling performance are considered. - Abstract: The Demonstration Fusion Power Reactor DEMO is the step foreseen to bridge the gap between ITER and the first commercial fusion power plant. One key element in the European work plan for DEMO is the elaboration of a conceptual design for a suitable core particle fuelling system. First considerations for such a system are presented in this contribution. Following the well-considered ITER solution, most analysis performed in this study assumes conventional pellet technology will be used for the fuelling system. However, taking advantage of the less compressed time frame for the DEMO project, several other techniques thought to bear potential for advanced fuelling performance are considered as well. In a first, basic analysis all actuation parameters at hand and their implications on the fuelling performance were considered. Tentative transport modeling of a reference scenario strongly indicates only particles deposited inside the plasma pedestal allow for efficient fuelling. Shallow edge fuelling results in an unbearable burden on the fuel cycle. Sufficiently deep particle deposition seems technically achievable, provided pellets are launched from the torus inboard at sufficient speed. All components required for a DEMO pellet system capable for high speed inboard pellet launch are already available or can be developed in due time with reasonable efforts. Furthermore, steps to integrate this solution into the EU DEMO model are taken.

  9. Synthetic Vision Systems - Operational Considerations Simulation Experiment

    Science.gov (United States)

    Kramer, Lynda J.; Williams, Steven P.; Bailey, Randall E.; Glaab, Louis J.

    2007-01-01

    Synthetic vision is a computer-generated image of the external scene topography that is generated from aircraft attitude, high-precision navigation information, and data of the terrain, obstacles, cultural features, and other required flight information. A synthetic vision system (SVS) enhances this basic functionality with real-time integrity to ensure the validity of the databases, perform obstacle detection and independent navigation accuracy verification, and provide traffic surveillance. Over the last five years, NASA and its industry partners have developed and deployed SVS technologies for commercial, business, and general aviation aircraft which have been shown to provide significant improvements in terrain awareness and reductions in the potential for Controlled-Flight-Into-Terrain incidents/accidents compared to current generation cockpit technologies. It has been hypothesized that SVS displays can greatly improve the safety and operational flexibility of flight in Instrument Meteorological Conditions (IMC) to a level comparable to clear-day Visual Meteorological Conditions (VMC), regardless of actual weather conditions or time of day. An experiment was conducted to evaluate SVS and SVS-related technologies as well as the influence of where the information is provided to the pilot (e.g., on a Head-Up or Head-Down Display) for consideration in defining landing minima based upon aircraft and airport equipage. The "operational considerations" evaluated under this effort included reduced visibility, decision altitudes, and airport equipage requirements, such as approach lighting systems, for SVS-equipped aircraft. Subjective results from the present study suggest that synthetic vision imagery on both head-up and head-down displays may offer benefits in situation awareness; workload; and approach and landing performance in the visibility levels, approach lighting systems, and decision altitudes tested.

  10. Considerations on the DEMO pellet fuelling system

    International Nuclear Information System (INIS)

    Lang, P.T.; Day, Ch.; Fable, E.; Igitkhanov, Y.; Köchl, F.; Mooney, R.; Pegourie, B.; Ploeckl, B.; Wenninger, R.; Zohm, H.

    2015-01-01

    Graphical abstract: - Highlights: • Considerations are made for a core particle fuelling system covering all DEMO requirements. • Particle deposition beyond the pedestal top is needed to achieve efficient fuelling. • Conventional pellet technology enabling launching from the torus inboard side can be used. • Efforts have been taken for integrating a suitable pellet guiding system into the EU DEMO model. • In addition, further techniques bearing potential for advanced fuelling performance are considered. - Abstract: The Demonstration Fusion Power Reactor DEMO is the step foreseen to bridge the gap between ITER and the first commercial fusion power plant. One key element in the European work plan for DEMO is the elaboration of a conceptual design for a suitable core particle fuelling system. First considerations for such a system are presented in this contribution. Following the well-considered ITER solution, most analysis performed in this study assumes conventional pellet technology will be used for the fuelling system. However, taking advantage of the less compressed time frame for the DEMO project, several other techniques thought to bear potential for advanced fuelling performance are considered as well. In a first, basic analysis all actuation parameters at hand and their implications on the fuelling performance were considered. Tentative transport modeling of a reference scenario strongly indicates only particles deposited inside the plasma pedestal allow for efficient fuelling. Shallow edge fuelling results in an unbearable burden on the fuel cycle. Sufficiently deep particle deposition seems technically achievable, provided pellets are launched from the torus inboard at sufficient speed. All components required for a DEMO pellet system capable for high speed inboard pellet launch are already available or can be developed in due time with reasonable efforts. Furthermore, steps to integrate this solution into the EU DEMO model are taken.

  11. STUDY ON SIMULATION METHOD OF AVALANCHE : FLOW ANALYSIS OF AVALANCHE USING PARTICLE METHOD

    OpenAIRE

    塩澤, 孝哉

    2015-01-01

    In this paper, modeling for the simulation of the avalanche by a particle method is discussed. There are two kinds of the snow avalanches, one is the surface avalanche which shows a smoke-like flow, and another is the total-layer avalanche which shows a flow like Bingham fluid. In the simulation of the surface avalanche, the particle method in consideration of a rotation resistance model is used. The particle method by Bingham fluid is used in the simulation of the total-layer avalanche. At t...

  12. CONSIDERATIONS ABOUT APPLICATION OF GRAPHICAL CALCULUS

    Directory of Open Access Journals (Sweden)

    Anghel Alina Angelica

    2015-06-01

    Full Text Available Some typical engineering problems can be solved using graphical methods in an integrated way for knowledge of design, mathematics, mechanics and physics. This paper presents some graphical methods which improve student’s performances on streigth of intuitive interpretation, visualization and understanding solutions of engineering problems. The increased use of graphical methods adds another layer of interpretation to a given task requiring the coordination of different knowledge, in order to produce a correct solution and to improve the product design.

  13. Energy research shows the way to sustainable energy policy

    International Nuclear Information System (INIS)

    Glatthard, T.

    2000-01-01

    This article takes a look at the work of the Swiss research programme on energy economics basics that aims to provide advice for policy makers. The programme investigates not only the technological but also the social and economic factors to be taken into consideration. In particular, the article reviews the programme's work on promotion strategies for sustainability in the energy area in connection with a proposed levy on energy. Examples are given of possible implementation strategies concerning new and existing buildings. The responsibilities of the parties to be involved in the implementation of promotional measures such as cantonal authorities, professional associations and agencies are discussed

  14. Show: Dr. H, the life and death of pancakes

    CERN Multimedia

    2012-01-01

    Dr. H, the life and death of pancakes, a comic theatrical creation, written and performed by Heiko Buchholz.   Monday 2 April 2012 in German Tuesday 3 April 2012 in English Wednesday 4 April 2012 in French 8:30 p.m. at the Globe of Science and Innovation. This production takes a comic look at scientific methods, as applied to a common object: the pancake. More specifically, Dr H. regales his audience with statistics, experiments and scientific data surrounding this egg-and-milk-based culinary delight. And although these zany sketches are nothing short of absurd, the audience is drawn in more often than you might expect… and taken on quite an unexpected journey into the behavioural disorders, personality quirks and psychoanalysis of the base pancake. This show playfully mocks scientific logic and discourse, forcing the audience to reflect on their gullibility in the face of science and its impenetrable jargon. It purports to be neither explanation nor illustration of scientific fact,...

  15. Large Payload Ground Transportation and Test Considerations

    Science.gov (United States)

    Rucker, Michelle A.

    2016-01-01

    Many spacecraft concepts under consideration by the National Aeronautics and Space Administration’s (NASA’s) Evolvable Mars Campaign take advantage of a Space Launch System payload shroud that may be 8 to 10 meters in diameter. Large payloads can theoretically save cost by reducing the number of launches needed--but only if it is possible to build, test, and transport a large payload to the launch site in the first place. Analysis performed previously for the Altair project identified several transportation and test issues with an 8.973 meters diameter payload. Although the entire Constellation Program—including Altair—has since been canceled, these issues serve as important lessons learned for spacecraft designers and program managers considering large payloads for future programs. A transportation feasibility study found that, even broken up into an Ascent and Descent Module, the Altair spacecraft would not fit inside available aircraft. Ground transportation of such large payloads over extended distances is not generally permitted, so overland transportation alone would not be an option. Limited ground transportation to the nearest waterway may be possible, but water transportation could take as long as 67 days per production unit, depending on point of origin and acceptance test facility; transportation from the western United States would require transit through the Panama Canal to access the Kennedy Space Center launch site. Large payloads also pose acceptance test and ground processing challenges. Although propulsion, mechanical vibration, and reverberant acoustic test facilities at NASA’s Plum Brook Station have been designed to accommodate large spacecraft, special handling and test work-arounds may be necessary, which could increase cost, schedule, and technical risk. Once at the launch site, there are no facilities currently capable of accommodating the combination of large payload size and hazardous processing such as hypergolic fuels

  16. Considerations in Starting Climate Change Research

    Science.gov (United States)

    Long, J. C. S.; Morgan, G.; Hamburg, S.; Winickoff, D. E.

    2014-12-01

    Many have called for climate engineering research because the growing risks of climate change and the geopolitical and national security risks of climate remediation technologies are real. As the topic of climate engineering remains highly controversial, national funding agencies should evaluate even modest outdoor climate engineering research proposals with respect to societal, legal, and risk considerations in making a decision to fund or not to fund. These concerns will be extremely difficult to coordinate internationally if they are not first considered successfully on a national basis. Assessment of a suite of proposed research projects with respect to these considerations indicates we would learn valuable lessons about how to govern research by initiating a few exemplar projects. The first time an issue arrives it can be very helpful if it there are specific cases, not a broad class of projects. A good first case should be defensible and understandable, fit within the general mandate of existing research programs, have negligible physical risk, small physical scale and short duration. By focusing on a specific case, the discussion can be held with limits and help to establish some track record in dealing with a controversial subject and developing a process for assigning appropriate scrutiny and outreach. Even at an early stage, with low risk, small-scale experiments, obtaining broad-based advice will aid in dealing with the controversies. An independent advisory body can provide guidance about a wide spectrum of physical and social risks of funding the experiment compared to societal benefit of gaining understanding. Clearly identifying the research as climate engineering research avoids sending research down a path that might violate public trust and provide an important opportunity to grow governance and public engagement at an early stage. Climate engineering research should be seen in the context of all approaches to dealing with the climate problem

  17. Researching the psychological therapies in prison: considerations and future recommendations.

    Science.gov (United States)

    Gee, Joanna; Bertrand-Godfrey, Betty

    2014-01-01

    The psychological therapies are widely considered within the forensic literature as holding a useful role in the prison system, however, despite this, very little research into the psychological therapies has taken place. Further, where research is carried out, it is often associated with the need for evidence-based practice (EBP), involving quantification and randomization. The paper aims to discuss these issues. This paper will initially introduce the importance of research into the psychological therapies in prison, followed by a consideration of EBP which can be thought of as the current movement governing research in the psychological therapies in the UK. However, in providing a focused critique of EBP, particularly within prisons, this paper will attempt to pave the way for a consideration of alternative research methodologies and resultant methods in researching the psychological therapies in prisons in the UK. Through this it is argued that research within the prison setting should act not to promote interventions and create an evidence-based as such, but to provide an accessible body of knowledge for the psychological therapists working in prisons in the UK.

  18. Seismic design considerations for nuclear fuel cycle facilities

    International Nuclear Information System (INIS)

    Soni, R.S.; Kushwaha, H.S.; Venkat Raj, V.

    2001-01-01

    During the last few decades, there have been considerable advances in the field of a seismic design of nuclear structures and components housed inside a Nuclear power Plant (NPP). The seismic design and qualification of theses systems and components are carried out through the use of well proven and established theoretical as well as experimental means. Many of the related research works pertaining to these methods are available in the published literature, codes, guides etc. Contrary to this, there is very little information available with regards to the seismic design aspects of the nuclear fuel cycle facilities. This is probably on account of the little importance attached to these facilities from the point of view of seismic loading. In reality, some of these facilities handle a large inventory of radioactive materials and, therefore, these facilities must survive during a seismic event without giving rise to any sort of undue radiological risk to the plant personnel and the public at large. Presented herein in this paper are the seismic design considerations which are adopted for the design of nuclear fuel cycle facilities in India. (author)

  19. The epigenetic effects of assisted reproductive technologies: ethical considerations.

    Science.gov (United States)

    Roy, M-C; Dupras, C; Ravitsky, V

    2017-08-01

    The use of assisted reproductive technologies (ART) has increased significantly, allowing many coping with infertility to conceive. However, an emerging body of evidence suggests that ART could carry epigenetic risks for those conceived through the use of these technologies. In accordance with the Developmental Origins of Health and Disease hypothesis, ART could increase the risk of developing late-onset diseases through epigenetic mechanisms, as superovulation, fertilization methods and embryo culture could impair the embryo's epigenetic reprogramming. Such epigenetic risks raise ethical issues for all stakeholders: prospective parents and children, health professionals and society. This paper focuses on ethical issues raised by the consideration of these risks when using ART. We apply two key ethical principles of North American bioethics (respect for autonomy and non-maleficence) and suggest that an ethical tension may emerge from conflicting duties to promote the reproductive autonomy of prospective parents on one hand, and to minimize risks to prospective children on the other. We argue that this tension is inherent to the entire enterprise of ART and thus cannot be addressed by individual clinicians in individual cases. We also consider the implications of the 'non-identity problem' in this context. We call for additional research that would allow a more robust evidence base for policy. We also call upon professional societies to provide clinicians with guidelines and educational resources to facilitate the communication of epigenetic risks associated with ART to patients, taking into consideration the challenges of communicating risk information whose validity is still uncertain.

  20. Considerations about the licensing process of special nuclear industrial facilities

    Energy Technology Data Exchange (ETDEWEB)

    Talarico, M.A., E-mail: talaricomarco@hotmail.com [Marinha do Brasil, Rio de Janeiro, RJ (Brazil). Coordenacao do Porgrama de Submarino com Propulsao Nuclear; Melo, P.F. Frutuoso e [Coordenacao dos Programas de Pos-Graduacao em Engenharia (COPPE/UFRJ), Rio de Janeiro, RJ (Brazil). Programa de Engenharia Nuclear

    2015-07-01

    This paper brings a discussion about the challenges involved in the development of a new kind of nuclear facility in Brazil, a naval base for nuclear submarines, with attention to the licensing process and considerations about the risk-informed decision making application to the licensing process. Initially, a model of such a naval base, called in this work, special industrial facility, is proposed, with its systems and respective sets of basic requirements, in order to make it possible the accomplishment of the special industrial facility support function to the nuclear submarine. A discussion about current challenges to overcome in this project is presented: the challenges due to the new characteristics of this type of nuclear facility; existence of several interfaces between the special industrial facilities systems and nuclear submarine systems in design activities; lack of specific regulation in Brazil to allow the licensing process of special industrial facilities by the nuclear safety authority; and comments about the lack of information from reference nuclear facilities, as is the case with nuclear power reactors (for example, the German Grafenrheinfeld nuclear plant is the reference plant for the Brazilian Angra 2 nuclear plant). Finally, in view of these challenges, an analysis method of special industrial facility operational scenarios to assist the licensing process is proposed. Also, considerations about the application of risk-informed decision making to the special industrial facility activity and licensing process in Brazil are presented. (author)

  1. Considerations about the licensing process of special nuclear industrial facilities

    International Nuclear Information System (INIS)

    Talarico, M.A.; Melo, P.F. Frutuoso e

    2015-01-01

    This paper brings a discussion about the challenges involved in the development of a new kind of nuclear facility in Brazil, a naval base for nuclear submarines, with attention to the licensing process and considerations about the risk-informed decision making application to the licensing process. Initially, a model of such a naval base, called in this work, special industrial facility, is proposed, with its systems and respective sets of basic requirements, in order to make it possible the accomplishment of the special industrial facility support function to the nuclear submarine. A discussion about current challenges to overcome in this project is presented: the challenges due to the new characteristics of this type of nuclear facility; existence of several interfaces between the special industrial facilities systems and nuclear submarine systems in design activities; lack of specific regulation in Brazil to allow the licensing process of special industrial facilities by the nuclear safety authority; and comments about the lack of information from reference nuclear facilities, as is the case with nuclear power reactors (for example, the German Grafenrheinfeld nuclear plant is the reference plant for the Brazilian Angra 2 nuclear plant). Finally, in view of these challenges, an analysis method of special industrial facility operational scenarios to assist the licensing process is proposed. Also, considerations about the application of risk-informed decision making to the special industrial facility activity and licensing process in Brazil are presented. (author)

  2. Ethical considerations on novel neuronal interfaces.

    Science.gov (United States)

    Keskinbora, Kadircan H; Keskinbora, Kader

    2018-04-01

    Wireless powered implants, each smaller than a grain of rice, have the potential to scan and stimulate brain cells. Further research may lead to next-generation brain-machine interfaces for controlling prosthetics, exoskeletons, and robots, as well as "electroceuticals" to treat disorders of the brain and body. In conditions that can be particularly alleviated with brain stimulation, the use of such mini devices may pose certain challenges. Health professionals are becoming increasingly more accountable in decision-making processes that have impacts on the life quality of individuals. It is possible to transmit such stimulation using remote control principles. Perhaps, the most important concern regarding the use of these devices termed as "neural dust" is represented by the possibility of controlling affection and other mental functions via waves reaching the brain using more advanced versions of such devices. This will not only violate the respect for authority principle of ethics, but also medical ethics, and may potentially lead to certain incidents of varying vehemence that may be considered illegal. Therefore, a sound knowledge and implementation of ethical principles is becoming a more important issue on the part of healthcare professionals. In both the ethical decision-making process and in ethical conflicts, it may be useful to re-appraise the principles of medical ethics. In this article, the ethical considerations of these devices are discussed.

  3. Siting considerations for LNG import terminals

    Energy Technology Data Exchange (ETDEWEB)

    Meratla, Z. [CDS Research Ltd., Vancouver, BC (Canada)

    2005-07-01

    Site selection criteria for liquefied natural gas (LNG) facilities and terminals were reviewed in this PowerPoint presentation. Onshore and offshore sites were discussed. Typical public opposition issues were examined, including public concerns over safety and the environment. Low key consultation processes with local communities was advised to assess levels of interest and opposition during initial stages. It was suggested that desirable LNG sites should not be visible from local communities. Remoteness from built-up areas was advised, as well as ensuring that sites meet the requirements of future expansion and large LNG carriers. Issues concerning waterway drawbacks and exclusion zones were examined, as well as the relative merits of onshore and offshore terminals. It was noted that onshore terminals are accessible to personnel as well as outside emergency response resources, and are less susceptible to weather related downtime. In addition, onshore spills are generally impounded. Offshore LNG import terminals are visible from shorelines and susceptible to stray marine traffic and abnormal events. Siting considerations for offshore facilities include sensitive areas; shipping channels; foundation issues; shipping lane access; and offshore pipeline lengths. Issues concerning loading arms, remote flare systems, integral ballast and process equipment for offshore facilities were discussed. Membrane type storage systems and tank construction details were presented as well as details of self supporting storage systems. A comparison of gravity-based structures and floating facilities was presented. It was concluded that floating LNG facilities have well developed security procedures, passive protection and automatic intruder detection alarms. tabs., figs.

  4. Nuclear energy center finance and ownership considerations

    International Nuclear Information System (INIS)

    Morris, J.A.; Wilder, R.P.

    1980-09-01

    Finance and ownership alternatives for a nuclear energy center (NEC) in South Carolina are analyzed in the context of the capital market and tax differences among alternatives. The ownership alternatives considered are (1) the private or private/public joint venture, (2) full public ownership and (3) a hybrid ownership form featuring federal involvement in the initial site development and permit phase, followed by a transition to private ownership. Public ownership is associated with considerably lower out-of-pocket costs than private ownership; the difference between the two, however, is related to subsidies from other parts of society to electricity customers of a publicly owned NEC. The attitudes of participating utilities on ownership forms are examined, with the finding of general strong opposition to increased federal involvement in the electric utility industry through NEC ownership. The conclusion is that the private-private/public joint venture is the preferable ownership form and that public ownership should be employed only if the private sector fails to respond to future energy demand

  5. Dietary protein considerations to support active aging.

    Science.gov (United States)

    Wall, Benjamin T; Cermak, Naomi M; van Loon, Luc J C

    2014-11-01

    Given our rapidly aging world-wide population, the loss of skeletal muscle mass with healthy aging (sarcopenia) represents an important societal and public health concern. Maintaining or adopting an active lifestyle alleviates age-related muscle loss to a certain extent. Over time, even small losses of muscle tissue can hinder the ability to maintain an active lifestyle and, as such, contribute to the development of frailty and metabolic disease. Considerable research focus has addressed the application of dietary protein supplementation to support exercise-induced gains in muscle mass in younger individuals. In contrast, the role of dietary protein in supporting the maintenance (or gain) of skeletal muscle mass in active older persons has received less attention. Older individuals display a blunted muscle protein synthetic response to dietary protein ingestion. However, this reduced anabolic response can largely be overcome when physical activity is performed in close temporal proximity to protein consumption. Moreover, recent evidence has helped elucidate the optimal type and amount of dietary protein that should be ingested by the older adult throughout the day in order to maximize the skeletal muscle adaptive response to physical activity. Evidence demonstrates that when these principles are adhered to, muscle maintenance or hypertrophy over prolonged periods can be further augmented in active older persons. The present review outlines the current understanding of the role that dietary protein occupies in the lifestyle of active older adults as a means to increase skeletal muscle mass, strength and function, and thus support healthier aging.

  6. ALARP considerations in criticality safety assessments

    International Nuclear Information System (INIS)

    Bowden, Russell L.; Barnes, Andrew; Thorne, Peter R.; Venner, Jack

    2003-01-01

    Demonstrating that the risk to the public and workers is As Low As Reasonably Practicable (ALARP) is a fundamental requirement of safety cases for nuclear facilities in the United Kingdom. This is embodied in the Safety Assessment Principles (SAPs) published by the Regulator, the essence of which is incorporated within the safety assessment processes of the various nuclear site licensees. The concept of ALARP within criticality safety assessments has taken some time to establish in the United Kingdom. In principle, the licensee is obliged to search for a deterministic criticality safety solution, such as safe geometry vessels and passive control features, rather than placing reliance on active measurement devices and plant administrative controls. This paper presents a consideration of some ALARP issues in relation to the development of criticality safety cases. The paper utilises some idealised examples covering a range of issues facing the criticality safety assessor, including new plant design, operational plant and decommissioning activities. These examples are used to outline the elements of the criticality safety cases and present a discussion of ALARP in the context of criticality safety assessments. (author)

  7. Enabling fast charging - Infrastructure and economic considerations

    Science.gov (United States)

    Burnham, Andrew; Dufek, Eric J.; Stephens, Thomas; Francfort, James; Michelbacher, Christopher; Carlson, Richard B.; Zhang, Jiucai; Vijayagopal, Ram; Dias, Fernando; Mohanpurkar, Manish; Scoffield, Don; Hardy, Keith; Shirk, Matthew; Hovsapian, Rob; Ahmed, Shabbir; Bloom, Ira; Jansen, Andrew N.; Keyser, Matthew; Kreuzer, Cory; Markel, Anthony; Meintz, Andrew; Pesaran, Ahmad; Tanim, Tanvir R.

    2017-11-01

    The ability to charge battery electric vehicles (BEVs) on a time scale that is on par with the time to fuel an internal combustion engine vehicle (ICEV) would remove a significant barrier to the adoption of BEVs. However, for viability, fast charging at this time scale needs to also occur at a price that is acceptable to consumers. Therefore, the cost drivers for both BEV owners and charging station providers are analyzed. In addition, key infrastructure considerations are examined, including grid stability and delivery of power, the design of fast charging stations and the design and use of electric vehicle service equipment. Each of these aspects have technical barriers that need to be addressed, and are directly linked to economic impacts to use and implementation. This discussion focuses on both the economic and infrastructure issues which exist and need to be addressed for the effective implementation of fast charging at 400 kW and above. In so doing, it has been found that there is a distinct need to effectively manage the intermittent, high power demand of fast charging, strategically plan infrastructure corridors, and to further understand the cost of operation of charging infrastructure and BEVs.

  8. Development Considerations for Nanocrystal Drug Products.

    Science.gov (United States)

    Chen, Mei-Ling; John, Mathew; Lee, Sau L; Tyner, Katherine M

    2017-05-01

    Nanocrystal technology has emerged as a valuable tool for facilitating the delivery of poorly water-soluble active pharmaceutical ingredients (APIs) and enhancing API bioavailability. To date, the US Food and Drug Administration (FDA) has received over 80 applications for drug products containing nanocrystals. These products can be delivered by different routes of administration and are used in a variety of therapeutic areas. To aid in identifying key developmental considerations for these products, a retrospective analysis was performed on the submissions received by the FDA to date. Over 60% of the submissions were for the oral route of administration. Based on the Biopharmaceutics Classification System (BCS), most nanocrystal drugs submitted to the FDA are class II compounds that possess low aqueous solubility and high intestinal permeability. Impact of food on drug bioavailability was reduced for most nanocrystal formulations as compared with their micronized counterparts. For all routes of administration, dose proportionality was observed for some, but not all, nanocrystal products. Particular emphasis in the development of nanocrystal products was placed on the in-process tests and controls at critical manufacturing steps (such as milling process), mitigation and control of process-related impurities, and the stability of APIs or polymorphic form (s) during manufacturing and upon storage. This emphasis resulted in identifying challenges to the development of these products including accurate determination of particle size (distribution) of drug substance and/or nanocrystal colloidal dispersion, identification of polymorphic form (s), and establishment of drug substance/product specifications.

  9. Considerations for the transportation of spent fuel

    International Nuclear Information System (INIS)

    Jefferson, R.M.

    1984-01-01

    In our society today the transportation of radioactive materials, and most particularly spent reactor fuel, is surrounded by considerable emotion and a wealth of information, good and bad. The transportation of these materials is viewed as unique and distinct from the transportation of other hazardous materials and as a particularly vulnerable component of the nuclear power activities of this nation. Added to this is the concept, widely held, that almost everyone is an expert on the transportation of radioactive materials. One significant contribution to this level of emotion is the notion that all roads (rail and highway), on which these goods will be transported, somehow traverse everyone's backyard. The issue of the transportation of spent fuel has thus become a political battleground. Perhaps this should not be surprising since it has all of the right characteristics for such politicization in that it is pervasive, emotional, and visible. In order that those involved in the discussion of this activity might be able to reach some rational conclusions, this paper offers some background information which might be useful to a broad range of individuals in developing their own perspectives. The intent is to address the safety of transporting spent fuel from a technical standpoint without the emotional content which is frequently a part of this argument

  10. Considerations for acceptability in Bible translation

    Directory of Open Access Journals (Sweden)

    Diphus C. Chemorion

    2009-09-01

    Full Text Available The ministry of Bible translation is an important component of the Great Commission (Matthew 28:18�20 and its mandate is to reach everyone with the word of God. One of the main goals of a Bible translation project is to produce a translation that will be used by the church in a given language group. Bible translation teams believe that the lives of the intended recipients will be changed positively when they gain access to Scripture in their own language. However, recent developments regarding Scripture use have shown that the success of any Bible translation project depends on whether or not its products are acceptable. If a translation is not acceptable to the intended audience, it may not be used, and as a result, it may fail to bring about the desired impact. This article explores the concept of �acceptability� as used in Bible translation and highlights important considerations that translators need to keep in mind in order to enhance the acceptability of their translation products.

  11. Marfan Syndrome: Clinical, Surgical, and Anesthetic Considerations.

    Science.gov (United States)

    Castellano, José M; Silvay, George; Castillo, Javier G

    2014-09-01

    Marfan syndrome is a multisystem connective tissue disorder, with primary involvement of the cardiovascular, ocular, and skeletal systems. This autosomal heritable disease is mainly attributable to a defect in the FBN1 gene. Clinical diagnosis of Marfan syndrome has been based on the Ghent criteria since 1996. In 2010, these criteria were updated, and the revised guidelines place more emphasis on aortic root dilation, ectopia lentis, and FBN1 mutation testing in the diagnostic assessment of Marfan syndrome. Among its many different clinical manifestations, cardiovascular involvement deserves special consideration, owing to its impact on prognosis. Recent molecular, surgical, and clinical research has yielded profound new insights into the pathological mechanisms that ultimately lead to tissue degradation and weakening of the aortic wall, which has led to exciting new treatment strategies. Furthermore, with the increasing life expectancy of patients with Marfan syndrome, there has been a subtle shift in the spectrum of medical problems. Consequently, this article focuses on recent advances to highlight their potential impact on future concepts of patient care from a clinical, surgical, and anesthetic perspective. © The Author(s) 2013.

  12. Cannabis for Chronic Pain: Challenges and Considerations.

    Science.gov (United States)

    Romero-Sandoval, E Alfonso; Fincham, Jack E; Kolano, Ashley L; Sharpe, Brandi; Alvarado-Vázquez, P Abigail

    2018-04-10

    The National Academies of Sciences, Engineering, and Medicine has found substantial evidence that cannabis (plant) is effective for the treatment of chronic pain in adults, and moderate evidence that oromucosal cannabinoids (extracts, especially nabiximols) improve short-term sleep disturbances in chronic pain. The paradoxical superiority of the cannabis plant over cannabinoid molecules represents a challenge for the medical community and the established processes that define modern pharmacy. The expanding and variable legalization of cannabis in multiple states nationwide represents an additional challenge for patients and the medical community because recreational and medicinal cannabis are irresponsibly overlapped. Cannabis designed for recreational use (containing high levels of active ingredients) is increasingly available to patients with chronic pain who do not find relief with current pharmacologic entities, which exposes patients to potential harm. This article analyzes the available scientific evidence to address controversial questions that the current state of cannabis poses for health-care professionals and chronic pain patients, and sets the basis for a more open discussion about the role of cannabis in modern medicine for pain management. A critical discussion on these points, the legal status of cannabis, and considerations for healthcare providers is presented. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

  13. Enabling fast charging – Vehicle considerations

    Energy Technology Data Exchange (ETDEWEB)

    Meintz, Andrew; Zhang, Jiucai; Vijayagopal, Ram; Kreutzer, Cory; Ahmed, Shabbir; Bloom, Ira; Burnham, Andrew; Carlson, Richard B.; Dias, Fernando; Dufek, Eric J.; Francfort, James; Hardy, Keith; Jansen, Andrew N.; Keyser, Matthew; Markel, Anthony; Michelbacher, Christopher; Mohanpurkar, Manish; Pesaran, Ahmad; Scoffield, Don; Shirk, Matthew; Stephens, Thomas; Tanim, Tanvir

    2017-11-01

    To achieve a successful increase in the plug-in battery electric vehicle (BEV) market, it is anticipated that a significant improvement in battery performance is required to improve the range that BEVs can travel and the rate at which they can be recharged. While the range that BEVs can travel on a single recharge is improving, the recharging rate is still much slower than the refueling rate of conventional internal combustion engine vehicles. To achieve comparable recharge times, we explore the vehicle considerations of charge rates of at least 400 kW. Faster recharge is expected to significantly mitigate the perceived deficiencies for long-distance transportation, to provide alternative charging in densely populated areas where overnight charging at home may not be possible, and to reduce range anxiety for travel within a city when unplanned charging may be required. This substantial increase in charging rate is expected to create technical issues in the design of the battery system and vehicle’s electrical architecture that must be resolved. This work focuses on battery system thermal design and total recharge time to meet the goals of implementing higher charge rates and the impacts of the expected increase in system voltage on the components of the vehicle.

  14. Radiobiological considerations in magna-field irradiation

    International Nuclear Information System (INIS)

    Evans, R.G.

    1983-01-01

    Radiobiological considerations are described for total body irradiation (TBI) as given to patients undergoing bone marrow transplantation (BMT). Although much progress has been made in the use of BMT for refractory leukemias, many patients still die from interstitial pneumonia and relapse. Fractionated TBI has been introduced in order to improve leukemic cell kill, while increasing the degree of normal tissue tolerance. Traditionally, bone marrow stem cells, leukemic cells and immunocytes have been considered as having a limited ability to repair radiation damage while cells of lung tissue and intestinal epithelial cells have a greater capacity. During fractionated radiation therapy or continuous low-dose rate exposure, repair of sublethal damage between fractions allows greater recovery in the cells of lung tissue to those in the bone marrow. Clinically, the potential benefit of six fractions over one fraction or low dose-rate TBI has yet to be proved, although there is suggestive evidence for a reduced incidence of interstitial pneumonitis. However, other extraneous factors such as doses to the lung, differences in conditioning regimens, effect of increased delay in BMT for patients receiving fractionated TBI, and the unmeasurable differences between institutions make definite conclusions impossible. Despite this, a consensus for dose fractionation has developed and most centers are moving away from the use of large single dose TBI

  15. Considerations relating to different types of packaging

    International Nuclear Information System (INIS)

    Sousselier, Y.; Cohendy, G.

    1976-01-01

    The transport of radioactive materials has never given rise to a serious accident in France. This is due to the high quality of the provisions contained in the Regulations and to the conscientious manner in which the latter are applied. However, it would now seem appropriate to re-examine certain of these provisions in the light of a number of minor incidents which have occurred, or merely because problems have arisen which did not exist at the time of the last revision. This applies particularly to Type B packaging, intended for irradiated fuel shipments whose considerable bulk calls for a mock-up study. The transport of Type B packaging by sea may pose the problem of its resistance to fire on normal merchant ships, and similarly its behaviour under the effect of crushing should be examined in the context of air transport. Industrial-type packaging likewise presents problems, although these are basically of a psychological nature. This is particularly the case with consignments of uraniferous concentrates, uranium hexafluoride and plutonium-contaminated wastes. The accumulation (which sometimes reaches substantial numbers) of Type A packaging on a single vehicle may involve consequences which also call for study. (author)

  16. Criteria Considerations for Establishment of Hems Operations

    Directory of Open Access Journals (Sweden)

    Borivoj Galović

    2007-05-01

    Full Text Available The importance of the "golden hour"; for optimal efficiencyof helicopter operations in emergency medical service (HEMSto meet the "golden hour" requirement the unconditional requirementis to establish a net of operational units to cover theentire area of the Republic of Croatia, capable to operate withinwide integrated area (international services. It is additionalback-up, not a competition to road and sea EMS vehicles. Therequired standards; HEMS operation, following complementarytraffic policy, i. e. complementary policy in line of trafficsystem integration within wider region, with reference to standards,must entirely comply with globally accepted standards.Republic of Croatia 's obvious objectives are traffic integrationinto EU (European Union traffic system. Cost analyses; It isstressed that coherent traffic policy can by certain instrumentsreduce traffic assigned external cost in national budget. Significanttraffic external cost includes cost of traffic accidents, environmentimpacts and traffic jams, and could be reduced byestablishmentof multi-purpose helicopter operations. SWOTanalyses should be made as for any other strategy or project.Technical-technological criteria and other considerations;Considering technical-technological criteria for relief of criticalsituations in traffic, it is obvious that one helicopter type cannotcomply to all multi-purpose requirements that traffic sets beforeus - EMS on open roads, sea, mountains and urban trafficcongested area, and search and rescue operations. However,common factor for all types is compliance to global standardsand regulations. In the paper, some examples of HEMS operationsin the EU States are mentioned.

  17. Stress and food allergy: mechanistic considerations.

    Science.gov (United States)

    Schreier, Hannah M C; Wright, Rosalind J

    2014-04-01

    Recent years have seen a marked increase in food allergy prevalence among children, particularly in Western countries, that cannot be explained by genetic factors alone. This has resulted in an increased effort to identify environmental risk factors underlying food allergies and to understand how these factors may be modified through interventions. Food allergy is an immune-mediated adverse reaction to food. Consequently, considerations of candidate risk factors have begun to focus on environmental influences that perturb the healthy development of the emerging immune system during critical periods of development (eg, prenatally and during early childhood), particularly in the gut. Given that psychosocial stress is known to play an important role in other allergic and inflammatory diseases, such as asthma, its potential role in food allergy is a growing area of research. However, research to date has largely focused on animal studies. This review synthesizes relevant animal research and epidemiological data, providing proof of concept for moderating influences of psychological stress on food allergy outcomes in humans. Pathways that may underlie associations between psychosocial stress and the expression of food allergy are discussed. Copyright © 2014 American College of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.

  18. Considerations in change management related to technology.

    Science.gov (United States)

    Luo, John S; Hilty, Donald M; Worley, Linda L; Yager, Joel

    2006-01-01

    The authors describe the complexity of social processes for implementing technological change. Once a new technology is available, information about its availability and benefits must be made available to the community of users, with opportunities to try the innovations and find them worthwhile, despite organizational resistances. The authors reviewed the literature from psychiatry, psychology, sociology, business, and technology to distill common denominators for success and failure related to implementing technology. Beneficial technological innovations that are simple to use and obviously save everyone time and effort are easy to inaugurate. However, innovations that primarily serve management rather than subordinates or front-line utilizers may fail, despite considerable institutional effort. This article reviews and outlines several of the more prominent theoretical models governing successful institutional change. Successful implementation of difficult technological changes requires visionary leadership that has carefully considered the benefits, consulted with influence leaders at all organizational levels to spot unintended consequences and sources of resistance, and developed a detailed plan and continuous quality assurance process to foster implementation over time.

  19. Photovoltaics in buildings: town planning considerations

    Energy Technology Data Exchange (ETDEWEB)

    Cradick, K.

    1999-07-01

    This report explores the significance of PV specifically from a town and country planning perspective. PV will become of interest to planners for a number of reasons. Installation of PV systems on the walls, roofs and windows of buildings will have implications for the design and appearance of buildings and the wider townscape. For this reason, it would be beneficial for the planning profession to have a general awareness of the rapidly expanding range of PV building products now available. A widespread use of the technology will raise a number of other practical planning considerations, such as the need to ensure that PV-equipped buildings are not overshadowed by subsequent development or maturing trees.The use of PV could bring planning benefits. For example, use of the technology could sometimes obviate the need to route overhead power supplies through sensitive landscapes to outlying rural settlement. As a renewable source of energy, the use of PV will be in harmony with Local Agenda 21 objectives and sustainability policies in development plans. This report is written for practising planners in local government, private practice and the voluntary sector, and has regard to the regulatory context within which planners operate. It does not seek to encourage members of the profession to exceed their powers by insisting upon the use of PV in new development. Instead, the report aims to provide an introduction to the technology so that planners may be conversant with the technology and understand both its potential and its limitations. (author)

  20. Consideration of environmental change in performance assessments

    International Nuclear Information System (INIS)

    Pinedo, P.; Thorne, M.; Egan, M.; Calvez, M.; Kautsky, U.

    2005-01-01

    Depending on the particular circumstances in which a post-closure performance assessment of a radioactive waste repository is made, it may be appropriate to follow simple or more complex approaches in characterising the biosphere. Several different Example Reference Biospheres were explored in BIOMASS Theme 1 to address a range of issues that arise. Here, consideration is given to Example Reference Biospheres relevant to representing the implications of changes that may occur within the biosphere system during the period over which releases of radionuclides from a disposal facility might take place. Mechanisms of change considered include those extrinsic and intrinsic to the system of interest. An overall methodology for incorporating environmental change into assessments is proposed. This includes screening of primary mechanisms of change; identification of possible time sequences of change; development of a coherent description of the regional landscape response for each time sequence; integration of source term and geosphere-biosphere interface information; identification and description of one or more time series of assessment biospheres; and evaluation of the advantages and disadvantages of simulating the effects of sequences of biosphere systems and the transitions between them, or of defining a set of biosphere systems to be represented individually in a non-sequential analysis. The usefulness of the methodology is explored in two site-specific examples and one generic example

  1. [Management of eyelid tumors: general considerations].

    Science.gov (United States)

    Lasudry, J

    2011-12-01

    Despite the fact that the majority of eyelid tumors are benign, proper management in daily practice requires detection of the malignant ones. Several clinical criteria are usually proposed to support or reject a hypothesis of malignancy; however, most are of limited reliability. In any case of doubt, outpatient biopsy is recommended, so as to establish the correct diagnosis and formulate the most appropriate treatment plan. In all facial malignancies, the first (and absolutely mandatory) consideration is control of the cancer. Then, restoration of eyelid function can be addressed, in the following order: protection of the globe by complete dynamic eyelid closure and opening, visual function (and prevention of possible deprivation amblyopia) by insuring a clear visual axis, correction of the tear film, efficient lachrymal drainage, and only then the role of the eyelids in facial expression and esthetics. For most malignant eyelid tumors, the best assurance of complete excision is obtained by extemporaneous examination of the resection margins by frozen section (by Mohs' micrographic surgery techniques, or a variation thereof). Currently, advancement and transposition flaps, possibly in combination with tarso-conjunctival or skin grafts, are the most utilised techniques. Despite the lack of histological verification, new treatment modalities, including topical chemotherapy, photodynamic therapy and cryotherapy, may provide interesting treatment options, particularly in collaboration with the dermatologist. Copyright © 2011 Elsevier Masson SAS. All rights reserved.

  2. Design Considerations for Developing Biodegradable Magnesium Implants

    Science.gov (United States)

    Brar, Harpreet S.; Keselowsky, Benjamin G.; Sarntinoranont, Malisa; Manuel, Michele V.

    The integration of biodegradable and bioabsorbable magnesium implants into the human body is a complex undertaking that faces major challenges. The complexity arises from the fact that biomaterials must meet both engineering and physiological requirements to ensure the desired properties. Historically, efforts have been focused on the behavior of commercial magnesium alloys in biological environments and their resultant effect on cell-mediated processes. Developing causal relationships between alloy chemistry and micro structure, and its effect on cellular behavior can be a difficult and time intensive process. A systems design approach driven by thermodynamics has the power to provide significant contributions in developing the next generation of magnesium alloy implants with controlled degradability, biocompatibility, and optimized mechanical properties, at reduced time and cost. This approach couples experimental research with theory and mechanistic modeling for the accelerated development of materials. The aim of this article is to enumerate this strategy, design considerations and hurdles for developing new magnesium alloys for use as biodegradable implant materials [1].

  3. 32 CFR 310.15 - General considerations.

    Science.gov (United States)

    2010-07-01

    ..., or other methods). The Privacy Act Statement consists of the elements set forth in paragraph (d)(2)of... easily understood. (4) The Privacy Act statement may appear as a public notice (sign or poster...

  4. Consideration on HRA implementation during LPSD operation

    International Nuclear Information System (INIS)

    Kim, Ar Ryum; Kim, Jae Whan; Jang, In Seok; Seong, Poong Hyun

    2014-01-01

    During low power and shutdown operation, it has been pointed out that the important of human actions is significantly increased. Because automatic control may be disabled, most control room annunciation titles indicate alarm status, and procedures are insufficient, human operators plays a much larger role during outages and in lower power state. In this regards, in order to reduce human errors and secure nuclear power plant safety, it is necessary to identify and estimate human errors during LPSD operations. However, many researchers have argued that there is no comprehensive LPSD human reliability analysis (HRA) method so far. In this study, we reviewed and implemented the existing HRA methods during LPSD operations: Korean standard HRA (K-HRA), Simplified plant analysis risk HRA (SPAR-H), Caused based decision tree (CBDT), and human cognitive reliability/ operator reliability experiments (HCR/ORE). We reviewed HRA methods based on several reports related to the unique aspects of human operator during LPSD operation and HRA requirements. In addition, the existing HRA methods were implemented during various plant operating states (POS) of LPSD operation. Loss of shutdown cooling system (SCS) was selected as initiating event. As a result of review and implementation of HRA methods, we derived the some limitations of the existing HRA methods and related procedure during loss of SCS event

  5. Surrounding information consideration promotes cooperation in Prisoner’s dilemma game

    International Nuclear Information System (INIS)

    Shu, Gang; Du, Xia; Li, Ya

    2016-01-01

    Highlights: • A new method of strategy updating is proposed in the Prisoner’s dilemma game. • The stochastic players only consider their neighbor’s payoff and update strategy by classical Fermi rule. • The advanced player would consider not only the neighbor’s payoff but also the neighbors’ local surrounding information. • The simulation result illustrates that with the increase of advanced players in the network, the fraction of cooperation increases. - Abstract: Evolutionary game theory provides a useful, integrative framework for studying the evolution of cooperation. A new strategy updating method is proposed in our model. Due to people with diversified thinking, players are divided into two categories based on their different strategy updating method: ordinary players and advanced players. The former players only consider their neighbor’s payoff and updating strategy by classical Fermi rule, while the latter players take both the neighbors’ surrounding information and payoff into account. The results show that the neighbors surrounding information consideration contributes to the evolution of cooperation and finds the fraction of cooperation grows evidently with the increase of advanced players numbers. Our model may provide a pragmatic approach to the research of cooperation in social network.

  6. Considerations for using data envelopment analysis for the assessment of radiotherapy treatment plan quality.

    Science.gov (United States)

    Simpson, John; Raith, Andrea; Rouse, Paul; Ehrgott, Matthias

    2017-10-09

    Purpose The operations research method of data envelopment analysis (DEA) shows promise for assessing radiotherapy treatment plan quality. The purpose of this paper is to consider the technical requirements for using DEA for plan assessment. Design/methodology/approach In total, 41 prostate treatment plans were retrospectively analysed using the DEA method. The authors investigate the impact of DEA weight restrictions with reference to the ability to differentiate plan performance at a level of clinical significance. Patient geometry influences plan quality and the authors compare differing approaches for managing patient geometry within the DEA method. Findings The input-oriented DEA method is the method of choice when performing plan analysis using the key undesirable plan metrics as the DEA inputs. When considering multiple inputs, it is necessary to constrain the DEA input weights in order to identify potential plan improvements at a level of clinical significance. All tested approaches for the consideration of patient geometry yielded consistent results. Research limitations/implications This work is based on prostate plans and individual recommendations would therefore need to be validated for other treatment sites. Notwithstanding, the method that requires both optimised DEA weights according to clinical significance and appropriate accounting for patient geometric factors is universally applicable. Practical implications DEA can potentially be used during treatment plan development to guide the planning process or alternatively used retrospectively for treatment plan quality audit. Social implications DEA is independent of the planning system platform and therefore has the potential to be used for multi-institutional quality audit. Originality/value To the authors' knowledge, this is the first published examination of the optimal approach in the use of DEA for radiotherapy treatment plan assessment.

  7. Security Considerations and Recommendations in Computer-Based Testing

    Directory of Open Access Journals (Sweden)

    Saleh M. Al-Saleem

    2014-01-01

    Full Text Available Many organizations and institutions around the globe are moving or planning to move their paper-and-pencil based testing to computer-based testing (CBT. However, this conversion will not be the best option for all kinds of exams and it will require significant resources. These resources may include the preparation of item banks, methods for test delivery, procedures for test administration, and last but not least test security. Security aspects may include but are not limited to the identification and authentication of examinee, the risks that are associated with cheating on the exam, and the procedures related to test delivery to the examinee. This paper will mainly investigate the security considerations associated with CBT and will provide some recommendations for the security of these kinds of tests. We will also propose a palm-based biometric authentication system incorporated with basic authentication system (username/password in order to check the identity and authenticity of the examinee.

  8. Data compression considerations for detectors with local intelligence

    International Nuclear Information System (INIS)

    Garcia-Sciveres, M; Wang, X

    2014-01-01

    This note summarizes the outcome of discussions about how data compression considerations apply to tracking detectors with local intelligence. The method for analyzing data compression efficiency is taken from a previous publication and applied to module characteristics from the WIT2014 workshop. We explore local intelligence and coupled layer structures in the language of data compression. In this context the original intelligent tracker concept of correlating hits to find matches of interest and discard others is just a form of lossy data compression. We now explore how these features (intelligence and coupled layers) can be exploited for lossless compression, which could enable full readout at higher trigger rates than previously envisioned, or even triggerless

  9. Security considerations and recommendations in computer-based testing.

    Science.gov (United States)

    Al-Saleem, Saleh M; Ullah, Hanif

    2014-01-01

    Many organizations and institutions around the globe are moving or planning to move their paper-and-pencil based testing to computer-based testing (CBT). However, this conversion will not be the best option for all kinds of exams and it will require significant resources. These resources may include the preparation of item banks, methods for test delivery, procedures for test administration, and last but not least test security. Security aspects may include but are not limited to the identification and authentication of examinee, the risks that are associated with cheating on the exam, and the procedures related to test delivery to the examinee. This paper will mainly investigate the security considerations associated with CBT and will provide some recommendations for the security of these kinds of tests. We will also propose a palm-based biometric authentication system incorporated with basic authentication system (username/password) in order to check the identity and authenticity of the examinee.

  10. Noninvasive Brain Stimulation and Personal Identity: Ethical Considerations.

    Science.gov (United States)

    Iwry, Jonathan; Yaden, David B; Newberg, Andrew B

    2017-01-01

    As noninvasive brain stimulation (NIBS) technology advances, these methods may become increasingly capable of influencing complex networks of mental functioning. We suggest that these might include cognitive and affective processes underlying personality and belief systems, which would raise important questions concerning personal identity and autonomy. We give particular attention to the relationship between personal identity and belief, emphasizing the importance of respecting users' personal values. We posit that research participants and patients should be encouraged to take an active approach to considering the personal implications of altering their own cognition, particularly in cases of neurocognitive "enhancement." We suggest that efforts to encourage careful consideration through the informed consent process would contribute usefully to studies and treatments that use NIBS.

  11. Noninvasive Brain Stimulation and Personal Identity: Ethical Considerations

    Directory of Open Access Journals (Sweden)

    Jonathan Iwry

    2017-06-01

    Full Text Available As noninvasive brain stimulation (NIBS technology advances, these methods may become increasingly capable of influencing complex networks of mental functioning. We suggest that these might include cognitive and affective processes underlying personality and belief systems, which would raise important questions concerning personal identity and autonomy. We give particular attention to the relationship between personal identity and belief, emphasizing the importance of respecting users' personal values. We posit that research participants and patients should be encouraged to take an active approach to considering the personal implications of altering their own cognition, particularly in cases of neurocognitive “enhancement.” We suggest that efforts to encourage careful consideration through the informed consent process would contribute usefully to studies and treatments that use NIBS.

  12. Arterial Stiffness in Children: Pediatric Measurement and Considerations

    Science.gov (United States)

    Savant, Jonathan D.; Furth, Susan L.; Meyers, Kevin E.C.

    2014-01-01

    Background Arterial stiffness is a natural consequence of aging, accelerated in certain chronic conditions, and predictive of cardiovascular events in adults. Emerging research suggests the importance of arterial stiffness in pediatric populations. Methods There are different indices of arterial stiffness. The present manuscript focuses on carotid-femoral pulse wave velocity and pulse wave analysis, although other methodologies are discussed. Also reviewed are specific measurement considerations for pediatric populations and the literature describing arterial stiffness in children with certain chronic conditions (primary hypertension, obesity, diabetes, chronic kidney disease, hypercholesterolemia, genetic syndromes involving vasculopathy, and solid organ transplant recipients). Conclusions The measurement of arterial stiffness in children is feasible and, under controlled conditions, can give accurate information about the underlying state of the arteries. This potentially adds valuable information about the functionality of the cardiovascular system in children with a variety of chronic diseases well beyond that of the brachial artery blood pressure. PMID:26587447

  13. User safety considerations in lithium thionyl chloride batteries

    Energy Technology Data Exchange (ETDEWEB)

    Johnson, L.J.; Willis, A.H.

    1981-01-01

    The mechanics of failure of lithium batteries with thionyl chloride as a catholyte are discussed, and methods available to provide user safety are outlined. Advantages of using the batteries are discussed, including a high cell voltage of 3.6 V, a high specific energy density greater than 200 W-hr per pound, excellent voltage stability over 95% of the discharge life of the cell, low cost materials, and a storage life up to 10 years. Safety problems such as explosion, venting, leaking, and short circuit overheating are also discussed. A fault matrix is presented to relate battery hazards to the possible use and disposal conditions, and to determine levels of safety for the user system. A test plan is also developed which includes mechanical, thermal, electrical and chemical considerations, and can be organized into categories convenient to various test facility capabilities.

  14. User safety considerations in lithium thionyl chloride batteries

    Science.gov (United States)

    Johnson, L. J.; Willis, A. H.

    The mechanics of failure of lithium batteries with thionyl chloride as a catholyte are discussed, and methods available to provide user safety are outlined. Advantages of using the batteries are discussed, including a high cell voltage of 3.6 V, a high specific energy density greater than 200 W-hr per pound, excellent voltage stability over 95% of the discharge life of the cell, low cost materials, and a storage life up to 10 years. Safety problems such as explosion, venting, leaking, and short circuit overheating are also discussed. A fault matrix is presented to relate battery hazards to the possible use and disposal conditions, and to determine levels of safety for the user system. A test plan is also developed which includes mechanical, thermal, electrical and chemical considerations, and can be organized into categories convenient to various test facility capabilities.

  15. Non-asthmatic patients show increased exhaled nitric oxide concentrations

    Directory of Open Access Journals (Sweden)

    Beatriz M. Saraiva-Romanholo

    2009-01-01

    Full Text Available OBJECTIVE: Evaluate whether exhaled nitric oxide may serve as a marker of intraoperative bronchospasm. INTRODUCTION: Intraoperative bronchospasm remains a challenging event during anesthesia. Previous studies in asthmatic patients suggest that exhaled nitric oxide may represent a noninvasive measure of airway inflammation. METHODS: A total of 146,358 anesthesia information forms, which were received during the period from 1999 to 2004, were reviewed. Bronchospasm was registered on 863 forms. From those, three groups were identified: 9 non-asthmatic patients (Bronchospasm group, 12 asthmatics (Asthma group and 10 subjects with no previous airway disease or symptoms (Control group. All subjects were submitted to exhaled nitric oxide measurements (parts/billion, spirometry and the induced sputum test. The data was compared by ANOVA followed by the Tukey test and Kruskal-Wallis followed by Dunn's test. RESULTS: The normal lung function test results for the Bronchospasm group were different from those of the asthma group (p <0.05. The median percentage of eosinophils in induced sputum was higher for the Asthma [2.46 (0.45-6.83] compared with either the Bronchospasm [0.55 (0-1.26] or the Control group [0.0 (0] (p <0.05; exhaled nitric oxide followed a similar pattern for the Asthma [81.55 (57.6-86.85], Bronchospasm [46.2 (42.0 -62.6] and Control group [18.7 (16.0-24.7] (p< 0.05. CONCLUSIONS: Non-asthmatic patients with intraoperative bronchospasm detected during anesthesia and endotracheal intubation showed increased expired nitric oxide.

  16. Consideration of dismantling operations in the design

    International Nuclear Information System (INIS)

    Dubourg; Bonin.

    1984-12-01

    This analysis shows that the parameters and the constraints taken into account at the design level to facilitate the exploitation and the maintenance make the dismantling and its preparation easier [fr

  17. 4 CFR 22.2 - Board Consideration [Rule 2].

    Science.gov (United States)

    2010-01-01

    ... 4 Accounts 1 2010-01-01 2010-01-01 false Board Consideration [Rule 2]. 22.2 Section 22.2 Accounts... OFFICE CONTRACT APPEALS BOARD § 22.2 Board Consideration [Rule 2]. (a) Offices. The office of the Board... consideration of a matter by all members of the Contract Appeals Board will not be granted in any appeal filed...

  18. 46 CFR 92.01-15 - Special consideration.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Special consideration. 92.01-15 Section 92.01-15 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CARGO AND MISCELLANEOUS VESSELS CONSTRUCTION AND ARRANGEMENT Hull Structure § 92.01-15 Special consideration. (a) Special consideration will be...

  19. 17 CFR 201.401 - Consideration of stays.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Consideration of stays. 201... PRACTICE Rules of Practice Appeal to the Commission and Commission Review § 201.401 Consideration of stays... consideration. Where the action complained of has already taken effect and the motion for stay is filed within...

  20. 46 CFR 72.01-20 - Special consideration.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 3 2010-10-01 2010-10-01 false Special consideration. 72.01-20 Section 72.01-20 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) PASSENGER VESSELS CONSTRUCTION AND ARRANGEMENT Hull Structure § 72.01-20 Special consideration. (a) Special consideration will be given to the...