WorldWideScience

Sample records for methods enable quality

  1. Methods and dimensions of electronic health record data quality assessment: enabling reuse for clinical research.

    Science.gov (United States)

    Weiskopf, Nicole Gray; Weng, Chunhua

    2013-01-01

    To review the methods and dimensions of data quality assessment in the context of electronic health record (EHR) data reuse for research. A review of the clinical research literature discussing data quality assessment methodology for EHR data was performed. Using an iterative process, the aspects of data quality being measured were abstracted and categorized, as well as the methods of assessment used. Five dimensions of data quality were identified, which are completeness, correctness, concordance, plausibility, and currency, and seven broad categories of data quality assessment methods: comparison with gold standards, data element agreement, data source agreement, distribution comparison, validity checks, log review, and element presence. Examination of the methods by which clinical researchers have investigated the quality and suitability of EHR data for research shows that there are fundamental features of data quality, which may be difficult to measure, as well as proxy dimensions. Researchers interested in the reuse of EHR data for clinical research are recommended to consider the adoption of a consistent taxonomy of EHR data quality, to remain aware of the task-dependence of data quality, to integrate work on data quality assessment from other fields, and to adopt systematic, empirically driven, statistically based methods of data quality assessment. There is currently little consistency or potential generalizability in the methods used to assess EHR data quality. If the reuse of EHR data for clinical research is to become accepted, researchers should adopt validated, systematic methods of EHR data quality assessment.

  2. Development of the high-order decoupled direct method in three dimensions for particulate matter: enabling advanced sensitivity analysis in air quality models

    Directory of Open Access Journals (Sweden)

    W. Zhang

    2012-03-01

    Full Text Available The high-order decoupled direct method in three dimensions for particulate matter (HDDM-3D/PM has been implemented in the Community Multiscale Air Quality (CMAQ model to enable advanced sensitivity analysis. The major effort of this work is to develop high-order DDM sensitivity analysis of ISORROPIA, the inorganic aerosol module of CMAQ. A case-specific approach has been applied, and the sensitivities of activity coefficients and water content are explicitly computed. Stand-alone tests are performed for ISORROPIA by comparing the sensitivities (first- and second-order computed by HDDM and the brute force (BF approximations. Similar comparison has also been carried out for CMAQ sensitivities simulated using a week-long winter episode for a continental US domain. Second-order sensitivities of aerosol species (e.g., sulfate, nitrate, and ammonium with respect to domain-wide SO2, NOx, and NH3 emissions show agreement with BF results, yet exhibit less noise in locations where BF results are demonstrably inaccurate. Second-order sensitivity analysis elucidates poorly understood nonlinear responses of secondary inorganic aerosols to their precursors and competing species. Adding second-order sensitivity terms to the Taylor series projection of the nitrate concentrations with a 50% reduction in domain-wide NOx or SO2 emissions rates improves the prediction with statistical significance.

  3. Development of the high-order decoupled direct method in three dimensions for particulate matter: enabling advanced sensitivity analysis in air quality models

    Directory of Open Access Journals (Sweden)

    W. Zhang

    2011-10-01

    Full Text Available The high-order decoupled direct method in three dimensions for particular matter (HDDM-3D/PM has been implemented in the Community Multiscale Air Quality (CMAQ model to enable advanced sensitivity analysis. The major effort of this work is to develop high-order DDM sensitivity analysis of ISORROPIA, the inorganic aerosol module of CMAQ. A case-specific approach has been applied, and the sensitivities of activity coefficients and water content are explicitly computed. Stand-alone tests are performed for ISORROPIA by comparing the sensitivities (first- and second-order computed by HDDM and the brute force (BF approximations. Similar comparison has also been carried out for CMAQ results simulated using a week-long winter episode for a continental US domain. Second-order sensitivities of aerosol species (e.g., sulfate, nitrate, and ammonium with respect to domain-wide SO2, NOx, and NH3 emissions show agreement with BF results, yet exhibit less noise in locations where BF results are demonstrably inaccurate. Second-order sensitivity analysis elucidates nonlinear responses of secondary inorganic aerosols to their precursors and competing species that have not yet been well-understood with other approaches. Including second-order sensitivity coefficients in the Taylor series projection of the nitrate concentrations with a 50% reduction in domain-wide NOx emission shows a statistically significant improvement compared to the first-order Taylor series projection.

  4. From image processing to classification: IV. Classification of electrophoretic patterns by neural networks and statistical methods enable quality assessment of wheat varieties for breadmaking

    DEFF Research Database (Denmark)

    Jensen, Kirsten; Kesmir, Can; Søndergaard, Ib

    1996-01-01

    The end-use quality of products made from doughs consisting of wheat flour and water is often dependent upon the storage (gluten) proteins of the grain endosperm. Today the electrophoretic patterns of the high molecular weight (HMW) glutenin subunits are used for quality selections in wheat...

  5. From image processing to classification: IV. Classification of electrophoretic patterns by neural networks and statistical methods enable quality assessment of wheat varieties for bread making

    DEFF Research Database (Denmark)

    Jensen, K.; Kesmir, Can; Søndergaard, Ib

    1996-01-01

    The end-use quality of products made from doughs consisting of wheat flour and water is often dependent upon the storage (gluten) proteins of the grain endosperm. Today the electrophoretic patterns of the high molecular weight (HMW) glutenin subunits are used for quality selections in wheat...

  6. 77 FR 42738 - Request for Information on Quality Measurement Enabled by Health IT

    Science.gov (United States)

    2012-07-20

    ... Enabled by Health IT AGENCY: Agency for Healthcare Research and Quality (AHRQ), Health and Human Services... information technology (IT) system developers, including vendors; payers, quality measure developers, end... regarding quality measurement enabled by health IT. Quality measurement--the assessment of the...

  7. Informatics methods to enable sharing of quantitative imaging research data.

    Science.gov (United States)

    Levy, Mia A; Freymann, John B; Kirby, Justin S; Fedorov, Andriy; Fennessy, Fiona M; Eschrich, Steven A; Berglund, Anders E; Fenstermacher, David A; Tan, Yongqiang; Guo, Xiaotao; Casavant, Thomas L; Brown, Bartley J; Braun, Terry A; Dekker, Andre; Roelofs, Erik; Mountz, James M; Boada, Fernando; Laymon, Charles; Oborski, Matt; Rubin, Daniel L

    2012-11-01

    The National Cancer Institute Quantitative Research Network (QIN) is a collaborative research network whose goal is to share data, algorithms and research tools to accelerate quantitative imaging research. A challenge is the variability in tools and analysis platforms used in quantitative imaging. Our goal was to understand the extent of this variation and to develop an approach to enable sharing data and to promote reuse of quantitative imaging data in the community. We performed a survey of the current tools in use by the QIN member sites for representation and storage of their QIN research data including images, image meta-data and clinical data. We identified existing systems and standards for data sharing and their gaps for the QIN use case. We then proposed a system architecture to enable data sharing and collaborative experimentation within the QIN. There are a variety of tools currently used by each QIN institution. We developed a general information system architecture to support the QIN goals. We also describe the remaining architecture gaps we are developing to enable members to share research images and image meta-data across the network. As a research network, the QIN will stimulate quantitative imaging research by pooling data, algorithms and research tools. However, there are gaps in current functional requirements that will need to be met by future informatics development. Special attention must be given to the technical requirements needed to translate these methods into the clinical research workflow to enable validation and qualification of these novel imaging biomarkers. Copyright © 2012 Elsevier Inc. All rights reserved.

  8. Systems and Methods for RFID-Enabled Pressure Sensing Apparatus

    Science.gov (United States)

    Fink, Patrick W. (Inventor); Lin, Gregory Y. (Inventor); Kennedy, Timothy F. (Inventor); Ngo, Phong H. (Inventor)

    2016-01-01

    Methods, apparatuses and systems for radio frequency identification (RFID)-enabled information collection are disclosed, including an enclosure, a collector coupled to the enclosure, an interrogator, a processor, and one or more RFID field sensors, each having an individual identification, disposed within the enclosure. In operation, the interrogator transmits an incident signal to the collector, causing the collector to generate an electromagnetic field within the enclosure. The electromagnetic field is affected by one or more influences. RFID sensors respond to the electromagnetic field by transmitting reflected signals containing the individual identifications of the responding RFID sensors to the interrogator. The interrogator receives the reflected signals, measures one or more returned signal strength indications ("RSSI") of the reflected signals and sends the RSSI measurements and identification of the responding RFID sensors to the processor to determine one or more facts about the influences. Other embodiments are also described.

  9. System and Method for RFID-Enabled Information Collection

    Science.gov (United States)

    Fink, Patrick W. (Inventor); Lin, Gregory Y. (Inventor); Kennedy, Timothy F. (Inventor); Ngo, Phong H. (Inventor); Byerly, Diane (Inventor)

    2016-01-01

    Methods, apparatuses and systems for radio frequency identification (RFID)-enabled information collection are disclosed, including an enclosure, a collector coupled to the enclosure, an interrogator, a processor, and one or more RFID field sensors, each having an individual identification, disposed within the enclosure. In operation, the interrogator transmits an incident signal to the collector, causing the collector to generate an electromagnetic field within the enclosure. The electromagnetic field is affected by one or more influences. RFID sensors respond to the electromagnetic field by transmitting reflected signals containing the individual identifications of the responding RFID sensors to the interrogator. The interrogator receives the reflected signals, measures one or more returned signal strength indications ("RSSI") of the reflected signals and sends the RSSI measurements and identification of the responding RFID sensors to the processor to determine one or more facts about the influences. Other embodiments are also described.

  10. Systems and Methods for RFID-Enabled Dispenser

    Science.gov (United States)

    Fink, Patrick W. (Inventor); Lin, Gregory Y. (Inventor); Kennedy, Timothy F. (Inventor); Ngo, Phong H. (Inventor); Byerly, Diane (Inventor)

    2015-01-01

    Methods, apparatuses and systems for radio frequency identification (RFID)-enabled information collection are disclosed, including an enclosure, a collector coupled to the enclosure, an interrogator, a processor, and one or more RFID field sensors, each having an individual identification, disposed within the enclosure. In operation, the interrogator transmits an incident signal to the collector, causing the collector to generate an electromagnetic field within the enclosure. The electromagnetic field is affected by one or more influences. RFID sensors respond to the electromagnetic field by transmitting reflected signals containing the individual identifications of the responding RFID sensors to the interrogator. The interrogator receives the reflected signals, measures one or more returned signal strength indications ("RSSI") of the reflected signals and sends the RSSI measurements and identification of the responding RFID sensors to the processor to determine one or more facts about the influences. Other embodiments are also described.

  11. Information System Quality Assessment Methods

    OpenAIRE

    Korn, Alexandra

    2014-01-01

    This thesis explores challenging topic of information system quality assessment and mainly process assessment. In this work the term Information System Quality is defined as well as different approaches in a quality definition for different domains of information systems are outlined. Main methods of process assessment are overviewed and their relationships are described. Process assessment methods are divided into two categories: ISO standards and best practices. The main objective of this w...

  12. Information System Quality Assessment Methods

    OpenAIRE

    2014-01-01

    This thesis explores challenging topic of information system quality assessment and mainly process assessment. In this work the term Information System Quality is defined as well as different approaches in a quality definition for different domains of information systems are outlined. Main methods of process assessment are overviewed and their relationships are described. Process assessment methods are divided into two categories: ISO standards and best practices. The main objective of this w...

  13. Quality of regularization methods

    NARCIS (Netherlands)

    Bouwman, J.

    1998-01-01

    The solution of ill-posed problems is non-trivial in the sense that frequently applied methods like least-squares fail. The ill-posedness of the problem is refiected by very small changes in the input data which may result in very large changes in the output data. Hence, some sort of stabilization

  14. Quality of regularization methods

    NARCIS (Netherlands)

    Bouwman, J.

    1998-01-01

    The solution of ill-posed problems is non-trivial in the sense that frequently applied methods like least-squares fail. The ill-posedness of the problem is refiected by very small changes in the input data which may result in very large changes in the output data. Hence, some sort of stabilization o

  15. A Voltage Quality Detection Method

    DEFF Research Database (Denmark)

    Chen, Zhe; Wei, Mu

    2008-01-01

    This paper presents a voltage quality detection method based on a phase-locked loop (PLL) technique. The technique can detect the voltage magnitude and phase angle of each individual phase under both normal and fault power system conditions. The proposed method has the potential to evaluate vario...... power quality disturbances, such as interruptions, sags and imbalances. Simulation studies have been performed. The effectiveness of the proposed method has been demonstrated under the simulated typical power disturbances....

  16. Quality Concerns in Technical Education in India: A Quantifiable Quality Enabled Model

    Science.gov (United States)

    Gambhir, Victor; Wadhwa, N. C.; Grover, Sandeep

    2016-01-01

    Purpose: The paper aims to discuss current Technical Education scenarios in India. It proposes modelling the factors affecting quality in a technical institute and then applying a suitable technique for assessment, comparison and ranking. Design/methodology/approach: The paper chose graph theoretic approach for quantification of quality-enabled…

  17. Eigenvector method for umbrella sampling enables error analysis.

    Science.gov (United States)

    Thiede, Erik H; Van Koten, Brian; Weare, Jonathan; Dinner, Aaron R

    2016-08-28

    Umbrella sampling efficiently yields equilibrium averages that depend on exploring rare states of a model by biasing simulations to windows of coordinate values and then combining the resulting data with physical weighting. Here, we introduce a mathematical framework that casts the step of combining the data as an eigenproblem. The advantage to this approach is that it facilitates error analysis. We discuss how the error scales with the number of windows. Then, we derive a central limit theorem for averages that are obtained from umbrella sampling. The central limit theorem suggests an estimator of the error contributions from individual windows, and we develop a simple and computationally inexpensive procedure for implementing it. We demonstrate this estimator for simulations of the alanine dipeptide and show that it emphasizes low free energy pathways between stable states in comparison to existing approaches for assessing error contributions. Our work suggests the possibility of using the estimator and, more generally, the eigenvector method for umbrella sampling to guide adaptation of the simulation parameters to accelerate convergence.

  18. Enabling methods for community health mapping in developing countries

    Directory of Open Access Journals (Sweden)

    Jacobsen Kathryn H

    2010-10-01

    Full Text Available Abstract Background Spatial epidemiology is useful but difficult to apply in developing countries due to the low availability of digitized maps and address systems, accurate population distributions, and computational tools. A community-based mapping approach was used to demonstrate that participatory geographic information system (PGIS techniques can provide information helpful for health and community development. Results The PGIS process allowed for the rapid determination of sectional (neighborhood boundaries within the city of Bo, Sierra Leone. When combined with data about hospital laboratory visits, a catchment area for one hospital in Bo could be established. A survey of households from within the catchment area determined that the average population per household (about 6 individuals was similar to that found in the 2004 census. However, we also found that the average house was inhabited by more than one household, for an average of 17.5 inhabitants per residential building, which is critical information to know when estimating population size using remote imagery that can detect and enumerate buildings. Conclusions The methods developed in this paper serve as a model for the involvement of communities in the generation of municipal maps and their application to community and health concerns.

  19. A Novel Synthesis of Computational Approaches Enables Optimization of Grasp Quality of Tendon-Driven Hands

    Science.gov (United States)

    Inouye, Joshua M.; Kutch, Jason J.; Valero-Cuevas, Francisco J.

    2013-01-01

    We propose a complete methodology to find the full set of feasible grasp wrenches and the corresponding wrench-direction-independent grasp quality for a tendon-driven hand with arbitrary design parameters. Monte Carlo simulations on two representative designs combined with multiple linear regression identified the parameters with the greatest potential to increase this grasp metric. This synthesis of computational approaches now enables the systematic design, evaluation, and optimization of tendon-driven hands. PMID:23335864

  20. Quality Control Analytical Methods: Method Validation.

    Science.gov (United States)

    Klang, Mark G; Williams, LaVonn A

    2016-01-01

    To properly determine the accuracy of a pharmaceutical product or compounded preparation, tests must be designed specifically for that evaluation. The procedures selected must be verified through a process referred to as method validation, an integral part of any good analytical practice. The results from a method validation procedure can be used to judge the quality, reliability, and consistency of analytical results. The purpose of this article is to deliver the message of the importance of validation of a pharmaceutical product or compounded preparation and to briefly discuss the results of a lack of such validation. Copyright© by International Journal of Pharmaceutical Compounding, Inc.

  1. Rheumatology Informatics System for Effectiveness: A National Informatics-Enabled Registry for Quality Improvement.

    Science.gov (United States)

    Yazdany, Jinoos; Bansback, Nick; Clowse, Megan; Collier, Deborah; Law, Karen; Liao, Katherine P; Michaud, Kaleb; Morgan, Esi M; Oates, James C; Orozco, Catalina; Reimold, Andreas; Simard, Julia F; Myslinski, Rachel; Kazi, Salahuddin

    2016-12-01

    The Rheumatology Informatics System for Effectiveness (RISE) is a national electronic health record (EHR)-enabled registry. RISE passively collects data from EHRs of participating practices, provides advanced quality measurement and data analytic capacities, and fulfills national quality reporting requirements. Here we report the registry's architecture and initial data, and we demonstrate how RISE is being used to improve the quality of care. RISE is a certified Centers for Medicare and Medicaid Services Qualified Clinical Data Registry, allowing collection of data without individual patient informed consent. We analyzed data between October 1, 2014 and September 30, 2015 to characterize initial practices and patients captured in RISE. We also analyzed medication use among rheumatoid arthritis (RA) patients and performance on several quality measures. Across 55 sites, 312 clinicians contributed data to RISE; 72% were in group practice, 21% in solo practice, and 7% were part of a larger health system. Sites contributed data on 239,302 individuals. Among the subset with RA, 34.4% of patients were taking a biologic or targeted synthetic disease-modifying antirheumatic drug (DMARD) at their last encounter, and 66.7% were receiving a nonbiologic DMARD. Examples of quality measures include that 55.2% had a disease activity score recorded, 53.6% a functional status score, and 91.0% were taking a DMARD in the last year. RISE provides critical infrastructure for improving the quality of care in rheumatology and is a unique data source to generate new knowledge. Data validation and mapping are ongoing and RISE is available to the research and clinical communities to advance rheumatology. © 2016, American College of Rheumatology.

  2. Enabling Continuous Quality Improvement in Practice: The Role and Contribution of Facilitation

    Science.gov (United States)

    Harvey, Gillian; Lynch, Elizabeth

    2017-01-01

    Facilitating the implementation of continuous quality improvement (CQI) is a complex undertaking. Numerous contextual factors at a local, organizational, and health system level can influence the trajectory and ultimate success of an improvement program. Some of these contextual factors are amenable to modification, others less so. As part of planning and implementing healthcare improvement, it is important to assess and build an understanding of contextual factors that might present barriers to or enablers of implementation. On the basis of this initial diagnosis, it should then be possible to design and implement the improvement intervention in a way that is responsive to contextual barriers and enablers, often described as “tailoring” the implementation approach. Having individuals in the active role of facilitators is proposed as an effective way of delivering a context-sensitive, tailored approach to implementing CQI. This paper presents an overview of the facilitator role in implementing CQI. Drawing on empirical evidence from the use of facilitator roles in healthcare, the type of skills and knowledge required will be considered, along with the type of facilitation strategies that can be employed in the implementation process. Evidence from both case studies and systematic reviews of facilitation will be reviewed and key lessons for developing and studying the role in the future identified. PMID:28275594

  3. Developing a TQM quality management method model

    OpenAIRE

    Zhang, Zhihai

    1997-01-01

    From an extensive review of total quality management literature, the external and internal environment affecting an organization's quality performance and the eleven primary elements of TQM are identified. Based on the primary TQM elements, a TQM quality management method model is developed. This model describes the primary quality management methods which may be used to assess an organization's present strengths and weaknesses with regard to its use of quality management methods. This model ...

  4. A Viewpoint on Wearable Technology-Enabled Measurement of Wellbeing and Health-Related Quality of Life in Parkinson's Disease.

    Science.gov (United States)

    van Uem, Janet M T; Isaacs, Tom; Lewin, Alan; Bresolin, Eros; Salkovic, Dina; Espay, Alberto J; Matthews, Helen; Maetzler, Walter

    2016-03-10

    In this viewpoint, we discuss how several aspects of Parkinson's disease (PD) - known to be correlated with wellbeing and health-related quality of life-could be measured using wearable devices ('wearables'). Moreover, three people with PD (PwP) having exhaustive experience with using such devices write about their personal understanding of wellbeing and health-related quality of life, building a bridge between the true needs defined by PwP and the available methods of data collection. Rapidly evolving new technologies develop wearables that probe function and behaviour in domestic environments of people with chronic conditions such as PD and have the potential to serve their needs. Gathered data can serve to inform patient-driven management changes, enabling greater control by PwP and enhancing likelihood of improvements in wellbeing and health-related quality of life. Data can also be used to quantify wellbeing and health-related quality of life. Additionally these techniques can uncover novel more sensitive and more ecologically valid disease-related endpoints. Active involvement of PwP in data collection and interpretation stands to provide personally and clinically meaningful endpoints and milestones to inform advances in research and relevance of translational efforts in PD.

  5. Using informatics-enabled quality improvement techniques to meet health record documentation requirements in radiology reports.

    Science.gov (United States)

    Prevedello, Luciano M; Farkas, Cameron; Dufault, Allen; Damiano, Maria; Doubilet, Peter; Khorasani, Ramin

    2013-08-01

    Medicare requires documented teaching physician involvement (attestation) in trainee-generated radiology reports. Automated attestation statement insertion in reports expedites the process but does not comply with requirements for active attestation. We evaluated an informatics-enabled quality improvement (QI) intervention to improve health record documentation requirements for active attestation. Institutional review board approval was not needed for this QI project performed in a 776-bed tertiary/quaternary teaching hospital. The intervention consisted of (1) policy requiring staff radiologists to actively attest to trainee-generated reports by personally activating a "macro" in the reporting system and (2) a semiautomated process to detect reports missing attestation; radiologists received daily e-mail reminders until the attestation statement was inserted. A random sample of 600 of 123,561 trainee-generated radiology reports created 17 months after the intervention (May 2011) was manually reviewed to determine attestation policy adherence. The number of attestation statements added in response to reminders throughout the entire study period was also evaluated. Trend analysis of the number of report addenda containing solely the attestation statement (proxy for missing initial attestation) was performed. Of 600 reports, 594 (99%) contained the attestation statement. Monthly attestations in response to email notifications decreased from 585 to 227 by the sixth month, a 2.6-fold reduction (P < .01). No significant trend was observed the following year, indicating a sustained effect. Informatics-enabled QI techniques resulted in 99% adherence to our teaching physician attestation policy with sustained results. Similar approaches may help improve adherence to other mandated performance measures in radiology reports. Copyright © 2013 AUR. Published by Elsevier Inc. All rights reserved.

  6. Visible quality aluminum and nickel superpolish polishing technology enabling new missions

    Science.gov (United States)

    Carrigan, Keith G.

    2011-06-01

    It is now well understood that with US Department of Defense (DoD) budgets shrinking and the Services and Agencies demanding new systems which can be fielded more quickly, cost and schedule are being emphasized more and more. At the same time, the US has ever growing needs for advanced capabilities to support evolving Intelligence, Surveillance and Reconnaissance objectives. In response to this market demand for ever more cost-effective, faster to market, single-channel, athermal optical systems, we have developed new metal polishing technologies which allow for short-lead, low-cost metal substrates to replace more costly, longer-lead material options. In parallel, the commercial marketplace is being driven continually to release better, faster and cheaper electronics. Growth according to Moore's law, enabled by advancements in photolithography, has produced denser memory, higher resolution displays and faster processors. While the quality of these products continues to increase, their price is falling. This seeming paradox is driven by industry advancements in manufacturing technology. The next steps on this curve can be realized via polishing technology which allows low-cost metal substrates to replace costly Silicon based optics for use in ultra-short wavelength systems.

  7. Improving the flexibility and profitability of ICT-enabled business networks: an assessment method and tool.

    NARCIS (Netherlands)

    D.J.E. Delporte-Vermeiren (Dominique)

    2003-01-01

    textabstractThis thesis deals with the development and the first empirical examination of an assessment method and decision support tool for the ex ante assessment of margin to be applied in ICT-enabled redesign of business networks. Many industries face the demand for customisation. This customisa

  8. AGILE METHODS AND QUALITY _ A SURVEY

    Directory of Open Access Journals (Sweden)

    BODJE N'Kauh Nathan-Regis

    2013-12-01

    Full Text Available Agile software processes, such as extreme programming (XP, Scrum, Lean, etc., rely on best practices that are considered to improve software development quality. It can be said that best practices aim to induce software quality assurance (SQA into the project at hand. Some researchers of agile methods claim that because of the very nature of such methods, quality in agile software projects should be a natural outcome of the applied method. As a consequence, agile quality is expected to be more or less embedded in the agile software processes. Many reports support and evangelize the advantages of agile methods with respect to quality assurance, Is it so ? An ambitious goal of this paper is to present work done to understand how quality is or should be handled. This paper as all survey papers attempt to summarize and organizes research results in the field of software engineering, precisely for the topic of agile methods related to software quality.

  9. Can Mobile-Enabled Payment Methods Reduce Petty Corruption in Urban Water Provision?

    Directory of Open Access Journals (Sweden)

    Aaron Krolikowski

    2014-02-01

    Full Text Available Corruption in the urban water sector constrains economic growth and human development in low-income countries. This paper empirically evaluates the ability of novel mobile-enabled payment methods to reduce information asymmetries and mitigate petty corruption in the urban water sector’s billing and payment processes. Overcoming these barriers may promote improved governance and water service delivery. The case of Dar es Salaam is used to explore the role of mobile-enabled payment instruments through the use of a stratified random sample of 1097 water utility customers and 42 interviews with representatives from the water sector, the telecommunications industry, civil society, and banking institutions. Results show that mobile-enabled payment methods can reduce information asymmetries and the incidence of petty corruption to promote improved financial management by making payment data more transparent and limiting the availability of economic rents in the billing and payment process. Implications for African urban water services include wider availability and more effective use of human and financial resources. These can be used to enhance water service delivery and citizen participation in the production of urban water supplies. The use of mobile-enabled payment methods in the urban water sector represents an application of mobile communication technologies in a low-income country with proven potential for scalability that simultaneously supports the achievement of development objectives.

  10. Developing a TQM quality management method model

    NARCIS (Netherlands)

    Zhang, Zhihai

    1997-01-01

    From an extensive review of total quality management literature, the external and internal environment affecting an organization's quality performance and the eleven primary elements of TQM are identified. Based on the primary TQM elements, a TQM quality management method model is developed. This mo

  11. Developing a TQM quality management method model

    NARCIS (Netherlands)

    Zhang, Zhihai

    1997-01-01

    From an extensive review of total quality management literature, the external and internal environment affecting an organization's quality performance and the eleven primary elements of TQM are identified. Based on the primary TQM elements, a TQM quality management method model is developed. This mo

  12. Developing a TQM quality management method model

    NARCIS (Netherlands)

    Zhang, Zhihai

    1997-01-01

    From an extensive review of total quality management literature, the external and internal environment affecting an organization's quality performance and the eleven primary elements of TQM are identified. Based on the primary TQM elements, a TQM quality management method model is developed. This

  13. Application Research of Ontology-enabled Process FMEA Knowledge Management Method

    OpenAIRE

    Zhao Xiuxu; Zhu Yuming

    2012-01-01

    Failure Mode and Effect Analysis (FMEA) is an important method to ensure the effectiveness of manufacturing process, which can prevent the happening of various potential failure. If the knowledge of FMEA can be accumulated and utilized reasonably, the quality management in manufacturing process will get decision support timely, and the efficiency of product quality problem analysis also can be improved. But, it is impossible to integrate the dispersive FMEA knowledge in the manufacturing proc...

  14. Enabling high-quality observations of surface imperviousness for water runoff modelling from unmanned aerial vehicles

    Science.gov (United States)

    Tokarczyk, Piotr; Leitao, Joao Paulo; Rieckermann, Jörg; Schindler, Konrad; Blumensaat, Frank

    2015-04-01

    Modelling rainfall-runoff in urban areas is increasingly applied to support flood risk assessment particularly against the background of a changing climate and an increasing urbanization. These models typically rely on high-quality data for rainfall and surface characteristics of the area. While recent research in urban drainage has been focusing on providing spatially detailed rainfall data, the technological advances in remote sensing that ease the acquisition of detailed land-use information are less prominently discussed within the community. The relevance of such methods increase as in many parts of the globe, accurate land-use information is generally lacking, because detailed image data is unavailable. Modern unmanned air vehicles (UAVs) allow acquiring high-resolution images on a local level at comparably lower cost, performing on-demand repetitive measurements, and obtaining a degree of detail tailored for the purpose of the study. In this study, we investigate for the first time the possibility to derive high-resolution imperviousness maps for urban areas from UAV imagery and to use this information as input for urban drainage models. To do so, an automatic processing pipeline with a modern classification method is tested and applied in a state-of-the-art urban drainage modelling exercise. In a real-life case study in the area of Lucerne, Switzerland, we compare imperviousness maps generated from a consumer micro-UAV and standard large-format aerial images acquired by the Swiss national mapping agency (swisstopo). After assessing their correctness, we perform an end-to-end comparison, in which they are used as an input for an urban drainage model. Then, we evaluate the influence which different image data sources and their processing methods have on hydrological and hydraulic model performance. We analyze the surface runoff of the 307 individual sub-catchments regarding relevant attributes, such as peak runoff and volume. Finally, we evaluate the model

  15. Quality Control Guidelines for SAM Chemical Methods

    Science.gov (United States)

    Learn more about quality control guidelines and recommendations for the analysis of samples using the chemistry methods listed in EPA's Selected Analytical Methods for Environmental Remediation and Recovery (SAM).

  16. Quality Control Guidelines for SAM Biotoxin Methods

    Science.gov (United States)

    Learn more about quality control guidelines and recommendations for the analysis of samples using the pathogen methods listed in EPA's Selected Analytical Methods for Environmental Remediation and Recovery (SAM).

  17. Quality Control Guidelines for SAM Radiochemical Methods

    Science.gov (United States)

    Learn more about quality control guidelines and recommendations for the analysis of samples using the radiochemistry methods listed in EPA's Selected Analytical Methods for Environmental Remediation and Recovery (SAM).

  18. Quality Control Guidelines for SAM Pathogen Methods

    Science.gov (United States)

    Learn more about quality control guidelines and recommendations for the analysis of samples using the biotoxin methods listed in EPA's Selected Analytical Methods for Environmental Remediation and Recovery (SAM).

  19. Multi-media Case Methods in Pre-service Science Education: Enabling an Apprenticeship for Praxis

    Science.gov (United States)

    Bencze, Larry; Hewitt, Jim; Pedretti, Erminia

    2001-04-01

    In recent years, teacher educators have looked to case methods as one means of bridging the theory-practice gap in university-based pre-service programs. This paper explores how case methods may be used to foster habits of praxis - that is, critical, reflective practice - that enable beginning teachers to adapt to the many diverse contexts they may encounter in the field. Our research used qualitative ethnographic methods to determine the efficacy of a case method designed to encourage critical analysis of a Year 8 science Optics lesson. Results suggest student teachers: (1) understood an associated analytical framework; (2) effectively analysed curriculum and pedagogy; and (3) exercised prudence in their assessment of the case. These findings tentatively indicate emerging habits of praxis. Notwithstanding such gains, we encourage designers of case-based curricula to: ensure case authenticity, protect subjects from critique and use multi-media case methods in conjunction with other approaches to promote habits of praxis.

  20. Fuzzy Design Method of Product Quality Robustness

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    In order to express information on the quality grade of product, designed, the target value of product quality design was described with a fuzzy number in this paper. The rule of robust design with a fuzzy target was analyzed with fuzzy probability theory,then the principle and modeling method of fuzzy robust design for a high quality product were put forward. With this new method used, the high-quality ratio of the product de-signed could be increased, and the ability to resist the influence of various disturbing fac-tors ang noise factors could be enhanced.

  1. Emerging technology: A key enabler for modernizing pharmaceutical manufacturing and advancing product quality.

    Science.gov (United States)

    O'Connor, Thomas F; Yu, Lawrence X; Lee, Sau L

    2016-07-25

    Issues in product quality have produced recalls and caused drug shortages in United States (U.S.) in the past few years. These quality issues were often due to outdated manufacturing technologies and equipment as well as lack of an effective quality management system. To ensure consistent supply of safe, effective and high-quality drug products available to the patients, the U.S. Food and Drug Administration (FDA) supports modernizing pharmaceutical manufacturing for improvements in product quality. Specifically, five new initiatives are proposed here to achieve this goal. They include: (i) advancing regulatory science for pharmaceutical manufacturing; (ii) establishing a public-private institute for pharmaceutical manufacturing innovation; (iii) creating incentives for investment in the technological upgrade of manufacturing processes and facilities; (iv) leveraging external expertise for regulatory quality assessment of emerging technologies; and (v) promoting the international harmonization of approaches for expediting the global adoption of emerging technologies.

  2. Method Enabling Gene Expression Studies of Pathogens in a Complex Food Matrix

    DEFF Research Database (Denmark)

    Kjeldgaard, Jette; Henriksen, Sidsel; Cohn, Marianne Thorup

    2011-01-01

    We describe a simple method for stabilizing and extracting high-quality prokaryotic RNA from meat. Heat and salt stress of Escherichia coli and Salmonella spp. in minced meat reproducibly induced dnaK and otsB expression, respectively, as observed by quantitative reverse transcription-PCR (>5-fold...

  3. A RAPID PCR-QUALITY DNA EXTRACTION METHOD IN FISH

    Institute of Scientific and Technical Information of China (English)

    LI Zhong; LIANG Hong-Wei; ZOU Gui-Wei

    2012-01-01

    PCR has been a general preferred method for biological research in fish, and previous research have enabled us to extract and purify PCR-quality DNA templates in laboratories[1-4]. The same problem among these procedures is waiting for tissue digesting for a long time. The overabundance time spent on PCR-quality DNA extraction restricts the efficiency of PCR assay, especially in large-scale PCR amplification, such as SSR-based genetic-mapping construction [5,6], identification of germ plasm resource[7,8] and evolution research [9,10], etc. In this study, a stable and rapid PCR-quality DNA extraction method was explored, using a modified alkaline lysis protocol. Extracting DNA for PCR only takes approximately 25 minutes. This stable and rapid DNA extraction method could save much laboratory time and promotes.%PCR has been a general preferred method for biological research in fish,and previous research have enabled us to extract and purify PCR-quality DNA templates in laboratories [1-4].The same problem among these procedures is waiting for tissue digesting for a long time.The overabundance time spent on PCR-quality DNA extraction restricts the efficiency of PCR assay,especially in large-scale PCR amplification,such as SSR-based genetic-mapping construction [5,6],identification of germ plasm resource[7,8] and evolution research [9,10],etc.In this study,a stable and rapid PCR-quality DNA extraction method was explored,using a modified alkaline lysis protocol.Extracting DNA for PCR only takes approximately 25 minutes.This stable and rapid DNA extraction method could save much laboratory time and promotes.

  4. A Microfluidic Immunostaining System Enables Quality Assured and Standardized Immunohistochemical Biomarker Analysis

    Science.gov (United States)

    Kwon, Seyong; Cho, Chang Hyun; Kwon, Youngmee; Lee, Eun Sook; Park, Je-Kyun

    2017-04-01

    Immunohistochemistry (IHC) plays an important role in biomarker-driven cancer therapy. Although there has been a high demand for standardized and quality assured IHC, it has rarely been achieved due to the complexity of IHC testing and the subjective validation-based process flow of IHC quality control. We present here a microfluidic immunostaining system for the standardization of IHC by creating a microfluidic linearly graded antibody (Ab)-staining device and a reference cell microarray. Unlike conventional efforts, our system deals primarily with the screening of biomarker staining conditions for quantitative quality assurance testing in IHC. We characterized the microfluidic matching of Ab staining intensity using three HER2 Abs produced by different manufacturers. The quality of HER2 Ab was also validated using tissues of breast cancer patients, demonstrating that our system is an efficient and powerful tool for the standardization and quality assurance of IHC.

  5. A Microfluidic Immunostaining System Enables Quality Assured and Standardized Immunohistochemical Biomarker Analysis

    Science.gov (United States)

    Kwon, Seyong; Cho, Chang Hyun; Kwon, Youngmee; Lee, Eun Sook; Park, Je-Kyun

    2017-01-01

    Immunohistochemistry (IHC) plays an important role in biomarker-driven cancer therapy. Although there has been a high demand for standardized and quality assured IHC, it has rarely been achieved due to the complexity of IHC testing and the subjective validation-based process flow of IHC quality control. We present here a microfluidic immunostaining system for the standardization of IHC by creating a microfluidic linearly graded antibody (Ab)-staining device and a reference cell microarray. Unlike conventional efforts, our system deals primarily with the screening of biomarker staining conditions for quantitative quality assurance testing in IHC. We characterized the microfluidic matching of Ab staining intensity using three HER2 Abs produced by different manufacturers. The quality of HER2 Ab was also validated using tissues of breast cancer patients, demonstrating that our system is an efficient and powerful tool for the standardization and quality assurance of IHC. PMID:28378835

  6. Microbiological methods for assessing soil quality

    NARCIS (Netherlands)

    Bloem, J.; Hopkins, D.W.; Benedetti, A.

    2006-01-01

    This book provides a selection of microbiological methods that are already applied in regional or national soil quality monitoring programs. It is split into two parts: part one gives an overview of approaches to monitoring, evaluating and managing soil quality. Part two provides a selection of meth

  7. Enabling Mobile Air Quality App Development with an AirNow API

    Science.gov (United States)

    Dye, T.; White, J. E.; Ludewig, S. A.; Dickerson, P.; Healy, A. N.; West, J. W.; Prince, L. A.

    2013-12-01

    The U.S. Environmental Protection Agency's (EPA) AirNow program works with over 130 participating state, local, and federal air quality agencies to obtain, quality control, and store real-time air quality observations and forecasts. From these data, the AirNow system generates thousands of maps and products each hour. Each day, information from AirNow is published online and in other media to assist the public in making health-based decisions related to air quality. However, an increasing number of people use mobile devices as their primary tool for obtaining information, and AirNow has responded to this trend by publishing an easy-to-use Web API that is useful for mobile app developers. This presentation will describe the various features of the AirNow application programming interface (API), including Representational State Transfer (REST)-type web services, file outputs, and RSS feeds. In addition, a web portal for the AirNow API will be shown, including documentation on use of the system, a query tool for configuring and running web services, and general information about the air quality data and forecasts available. Data published via the AirNow API includes corresponding Air Quality Index (AQI) levels for each pollutant. We will highlight examples of mobile apps that are using the AirNow API to provide location-based, real-time air quality information. Examples will include mobile apps developed for Minnesota ('Minnesota Air') and Washington, D.C. ('Clean Air Partners Air Quality'), and an app developed by EPA ('EPA AirNow').

  8. Developing methods of controlling quality costs

    Directory of Open Access Journals (Sweden)

    Gorbunova A. V.

    2017-01-01

    Full Text Available The article examines issues of managing quality costs, problems of applying economic methods of quality control, implementation of progressive methods of quality costs management in enterprises with the view of improving the efficiency of their evaluation and analysis. With the aim of increasing the effectiveness of the cost management mechanism, authors introduce controlling as a tool of deviation analysis from the standpoint of the process approach. A list of processes and corresponding evaluation criteria in the quality management system of enterprises is introduced. Authors also introduce the method of controlling quality costs and propose it for the practical application, which allows them to determine useful and unnecessary costs at the existing operating plant. Implementing the proposed recommendations in the system of cost management at an enterprise will allow to improve productivity of processes operating and reduce wasted expense on the quality of the process on the basis of determining values of useful and useless costs of quality according to criteria of processes functioning in the system of quality management.

  9. Implementation and Methods of Project Learning in Quantity Surveying Firms: Barriers, Enablers and Success Factors

    Directory of Open Access Journals (Sweden)

    Hamzah Abdul-Rahman

    2011-01-01

    Full Text Available Problem statement: Learning from project is vital for organizations to achieve competition and to survive in a dynamic environment. However, learning is not an easy task because there is no specific way for learning from projects. Besides, the practice of project learning and transfer knowledge to the firm’s level is still vague, specifically in the construction milieu. Approach: A questionnaire survey was conducted targeted quantity surveying firms in Malaysia, attempted to identify methods of learning from projects and implement this approach successfully. Interviews with experts in construction projects were conducted to expand and validate the results of the survey. Results: The findings indicated that on-the-job training is the preferable method to learn from construction project in quantity surveying firms. In addition, top management support and employee participants are the main enablers/barriers of project learning implementation. While, top management support found to be the main key success factor of project learning implementation. Conclusion/Recommendations: Determining barriers and enablers of learning showed how construction organization could implement learning from project successfully. This adds a practical tool of promoting learning in the field of organizational learning in construction. Results can be replicated in different industries to observe the disparity in each setting.

  10. Methods to enable the design of bioactive small molecules targeting RNA

    Science.gov (United States)

    Disney, Matthew D.; Yildirim, Ilyas; Childs-Disney, Jessica L.

    2014-01-01

    RNA is an immensely important target for small molecule therapeutics or chemical probes of function. However, methods that identify, annotate, and optimize RNA-small molecule interactions that could enable the design of compounds that modulate RNA function are in their infancies. This review describes recent approaches that have been developed to understand and optimize RNA motif-small molecule interactions, including Structure-Activity Relationships Through Sequencing (StARTS), quantitative structure-activity relationships (QSAR), chemical similarity searching, structure-based design and docking, and molecular dynamics (MD) simulations. Case studies described include the design of small molecules targeting RNA expansions, the bacterial A-site, viral RNAs, and telomerase RNA. These approaches can be combined to afford a synergistic method to exploit the myriad of RNA targets in the transcriptome. PMID:24357181

  11. Sequencing quality assessment tools to enable data-driven informatics for high throughput genomics

    Directory of Open Access Journals (Sweden)

    Richard Mark Leggett

    2013-12-01

    Full Text Available The processes of quality assessment and control are an active area of research at The Genome Analysis Centre (TGAC. Unlike other sequencing centres that often concentrate on a certain species or technology, TGAC applies expertise in genomics and bioinformatics to a wide range of projects, often requiring bespoke wet lab and in silico workflows. TGAC is fortunate to have access to a diverse range of sequencing and analysis platforms, and we are at the forefront of investigations into library quality and sequence data assessment. We have developed and implemented a number of algorithms, tools, pipelines and packages to ascertain, store, and expose quality metrics across a number of next-generation sequencing platforms, allowing rapid and in-depth cross-platform QC bioinformatics. In this review, we describe these tools as a vehicle for data-driven informatics, offering the potential to provide richer context for downstream analysis and to inform experimental design.

  12. Steel mill products analysis using qualities methods

    Directory of Open Access Journals (Sweden)

    B. Gajdzik

    2016-10-01

    Full Text Available The article presents the subject matter of steel mill product analysis using quality tools. The subject of quality control were bolts and a ball bushing. The Pareto chart and fault mode and effect analysis (FMEA were used to assess faultiness of the products. The faultiness analysis in case of the bolt enabled us to detect the following defects: failure to keep the dimensional tolerance, dents and imprints, improper roughness, lack of pre-machining, non-compatibility of the electroplating and faults on the surface. Analysis of the ball bushing has also revealed defects such as: failure to keep the dimensional tolerance, dents and imprints, improper surface roughness, lack of surface premachining as well as sharp edges and splitting of the material.

  13. An Android-enabled mobile framework for ensuring quality of life through patient-centric care.

    Science.gov (United States)

    Koufi, Vassiliki; Malamateniou, Flora; Vassilacopoulos, George

    2012-01-01

    The drive to achieve excellence in healthcare delivery while containing costs, underlies the need for a new generation of applications which facilitate the realization of a patient-centric care model. Under this emerging care model healthcare delivery can be integrated across the continuum of services, from prevention to follow up, and care can be coordinated across all settings. With care moving out into the community, health systems require real-time information to deliver coordinated care to patients. The integration of leading-edge technologies, such as mobile technology, with Personal Health Records (PHRs) can meet this requirement by making comprehensive and unified health information available to authorized users at any point of care or decision making through familiar environments such as Google's Android. This paper presents a framework that provides ubiquitous access to patients' PHRs via Android-enabled mobile devices. Where possible health information access and management is performed in a transparent way, thus enabling healthcare professionals to devote more time on practicing medicine and patients to manage their own health with the least possible intervention. This depends heavily on the context, which is collected by both Android-specific core system services and special purpose software agents with the latter being also responsible for preserving PHR data privacy.

  14. A method enabling simultaneous pressure and temperature measurement using a single piezoresistive MEMS pressure sensor

    Science.gov (United States)

    Frantlović, Miloš; Jokić, Ivana; Lazić, Žarko; Smiljanić, Milče; Obradov, Marko; Vukelić, Branko; Jakšić, Zoran; Stanković, Srđan

    2016-12-01

    In this paper we present a high-performance, simple and low-cost method for simultaneous measurement of pressure and temperature using a single piezoresistive MEMS pressure sensor. The proposed measurement method utilizes the parasitic temperature sensitivity of the sensing element for both pressure measurement correction and temperature measurement. A parametric mathematical model of the sensor was established and its parameters were calculated using the obtained characterization data. Based on the model, a real-time sensor correction for both pressure and temperature measurements was implemented in a target measurement system. The proposed method was verified experimentally on a group of typical industrial-grade piezoresistive sensors. The obtained results indicate that the method enables the pressure measurement performance to exceed that of typical digital industrial pressure transmitters, achieving at the same time the temperature measurement performance comparable to industrial-grade platinum resistance temperature sensors. The presented work is directly applicable in industrial instrumentation, where it can add temperature measurement capability to the existing pressure measurement instruments, requiring little or no additional hardware, and without adverse effects on pressure measurement performance.

  15. Optical methods for enabling focus cues in head-mounted displays for virtual and augmented reality

    Science.gov (United States)

    Hua, Hong

    2017-05-01

    Developing head-mounted displays (HMD) that offer uncompromised optical pathways to both digital and physical worlds without encumbrance and discomfort confronts many grand challenges, both from technological perspectives and human factors. Among the many challenges, minimizing visual discomfort is one of the key obstacles. One of the key contributing factors to visual discomfort is the lack of the ability to render proper focus cues in HMDs to stimulate natural eye accommodation responses, which leads to the well-known accommodation-convergence cue discrepancy problem. In this paper, I will provide a summary on the various optical methods approaches toward enabling focus cues in HMDs for both virtual reality (VR) and augmented reality (AR).

  16. Reference compensation method for enabling dispatchability of the wind power generation using battery energy storage system

    Directory of Open Access Journals (Sweden)

    Youngho Cho

    2016-01-01

    Full Text Available Due to intermittent characteristics of wind power generation, battery energy storage system (BESS has been exploited for decreasing the adverse impact of wind power output on the grid. This paper focuses on the BESS operation strategy called reference compensation for dispatchable wind. By adaptively compensating a reference signal that is typically set to be an average forecasted wind power for certain duration, the BESS maintains its SOC within a proper range, avoiding the non-compliant BESS when it is required to be charged or discharged because it is already fully charged or discharged, respectively, due to the unavoidable forecast errors. The proposed method has been applied to the real world wind farm data which is scaled down for the simulation in order to demonstrate its effectiveness of the proposed method. Simulation results demonstrate that the proposed method can decrease the operation suspension due to non-functioning BESS and keep the BESS on, and help thus enable the wind dispatchability.

  17. A highly parallel method for synthesizing DNA repeats enables the discovery of 'smart' protein polymers.

    Science.gov (United States)

    Amiram, Miriam; Quiroz, Felipe Garcia; Callahan, Daniel J; Chilkoti, Ashutosh

    2011-02-01

    Robust high-throughput synthesis methods are needed to expand the repertoire of repetitive protein-polymers for different applications. To address this need, we developed a new method, overlap extension rolling circle amplification (OERCA), for the highly parallel synthesis of genes encoding repetitive protein-polymers. OERCA involves a single PCR-type reaction for the rolling circle amplification of a circular DNA template and simultaneous overlap extension by thermal cycling. We characterized the variables that control OERCA and demonstrated its superiority over existing methods, its robustness, high-throughput and versatility by synthesizing variants of elastin-like polypeptides (ELPs) and protease-responsive polymers of glucagon-like peptide-1 analogues. Despite the GC-rich, highly repetitive sequences of ELPs, we synthesized remarkably large genes without recursive ligation. OERCA also enabled us to discover 'smart' biopolymers that exhibit fully reversible thermally responsive behaviour. This powerful strategy generates libraries of repetitive genes over a wide and tunable range of molecular weights in a 'one-pot' parallel format.

  18. Distributor pricing approaches enabled in Smart Grid to differentiate delivery service quality

    Directory of Open Access Journals (Sweden)

    Zhongwei Jake Zhang

    2014-12-01

    Full Text Available Industry practitioners who advocate retail competition and Demand-side Participation now look for approaches to link both initiatives through distributor pricing. As distributors incrementally convert more traditional assets into Smart Grid assets, they also need to consider different pricing approaches to recover the investment costs and meet the regulatory business requirements. Small electricity consumers need incentives to take part in these initiatives but their delivery service quality should also be closely guarded. Hence this paper addresses the above needs as a whole and investigates a set of distributor pricing approaches with Smart Grid technologies. Pricing of network and non-network based solutions should follow the incremental basis, such as the long run average incremental cost (LRAIC. The benefit of deferring network investment is calculated and should be passed to consumers as peak pricing rebate. A concept of reliability premium (RP based on load point reliability index is proposed, through which customers can express their preference of service quality and adjust their network tariff payment accordingly. A service delivery model is also proposed to utilize the savings from wholesale market trading to compensate for the downgraded service when loads are controlled. The IEEE 123-node distribution test feeder and the IEEE distribution system for RBTS Bus No. 2 are simulated, and solved using General Algebraic Modeling System (GAMS to demonstrate the proposed distributor pricing approaches in Smart Grid.

  19. Controllable Edge Oxidation and Bubbling Exfoliation Enable the Fabrication of High Quality Water Dispersible Graphene

    Science.gov (United States)

    Tian, Suyun; Sun, Jing; Yang, Siwei; He, Peng; Wang, Gang; di, Zengfeng; Ding, Guqiao; Xie, Xiaoming; Jiang, Mianheng

    2016-09-01

    Despite significant progresses made on mass production of chemically exfoliated graphene, the quality, cost and environmental friendliness remain major challenges for its market penetration. Here, we present a fast and green exfoliation strategy for large scale production of high quality water dispersible few layer graphene through a controllable edge oxidation and localized gas bubbling process. Mild edge oxidation guarantees that the pristine sp2 lattice is largely intact and the edges are functionalized with hydrophilic groups, giving rise to high conductivity and good water dispersibility at the same time. The aqueous concentration can be as high as 5.0 mg mL‑1, which is an order of magnitude higher than previously reports. The water soluble graphene can be directly spray-coated on various substrates, and the back-gated field effect transistor give hole and electron mobility of ~496 and ~676 cm2 V‑1 s‑1, respectively. These results achieved are expected to expedite various applications of graphene.

  20. Controllable Edge Oxidation and Bubbling Exfoliation Enable the Fabrication of High Quality Water Dispersible Graphene

    Science.gov (United States)

    Tian, Suyun; Sun, Jing; Yang, Siwei; He, Peng; Wang, Gang; Di, Zengfeng; Ding, Guqiao; Xie, Xiaoming; Jiang, Mianheng

    2016-01-01

    Despite significant progresses made on mass production of chemically exfoliated graphene, the quality, cost and environmental friendliness remain major challenges for its market penetration. Here, we present a fast and green exfoliation strategy for large scale production of high quality water dispersible few layer graphene through a controllable edge oxidation and localized gas bubbling process. Mild edge oxidation guarantees that the pristine sp2 lattice is largely intact and the edges are functionalized with hydrophilic groups, giving rise to high conductivity and good water dispersibility at the same time. The aqueous concentration can be as high as 5.0 mg mL−1, which is an order of magnitude higher than previously reports. The water soluble graphene can be directly spray-coated on various substrates, and the back-gated field effect transistor give hole and electron mobility of ~496 and ~676 cm2 V−1 s−1, respectively. These results achieved are expected to expedite various applications of graphene. PMID:27666869

  1. Proposing Some New Ecliptics in New Testament Studies Enabled by Digital Humanities-Based Methods

    Directory of Open Access Journals (Sweden)

    James Libby

    2016-04-01

    Full Text Available “Fragmentation” is a well-worn watchword in contemporary biblical studies. But is endless fragmentation across the traditional domains of epistemology, methodology and hermeneutics the inevitable future for the postmodern exercise of biblical scholarship? In our view, multiple factors mitigate against such a future, but two command our attention here. First, digital humanities itself, through its principled use of corpora, databases and computer-based methods, seems to be remarkably capable of producing findings with high levels of face validity (interpretive agreement across multiple hermeneutical perspectives and communities. Second, and perhaps more subversively, there is a substantial body of practitioners that, per Kearney, actively question postmodernity’s impress as the final port of call for philosophy. For these practitioners deconstruction has become both indispensable — by delegitimizing hegemonies — but, in its own way, metanarratival by stultifying all other iterative, dialectical and critical processes that have historically motivated scholarship. Sensing this impasse, Kearney (1987, pp. 43-45 proposes a reimagining that is not only critical but that also embraces ποίησις, the possibility of optimistic, creative work. Such a stance within digital humanities would affirm that poietic events emerge not only through frictions and fragmentation (e.g. Kinder and McPherson 2014, pp. xiii-xviii but also through commonalties and convergence. Our approach here will be to demonstrate such a reimagining, rather than to argue for it, using two worked examples in the Greek New Testament (GNT. Those examples – digital humanities-enabled papyrology and digital humanities-enabled statistical linguistics – demonstrate ways in which the data of the text itself can be used to interrogate our perspectives and suggest that our perspectives must remain ever open to such inquiries. We conclude with a call for digital humanities to

  2. Quality and methods of developing practice guidelines

    Directory of Open Access Journals (Sweden)

    Clark Otavio

    2002-01-01

    Full Text Available Abstract Background It is not known whether there are differences in the quality and recommendations between evidence-based (EB and consensus-based (CB guidelines. We used breast cancer guidelines as a case study to assess for these differences. Methods Five different instruments to evaluate the quality of guidelines were identified by a literature search. We also searched MEDLINE and the Internet to locate 8 breast cancer guidelines. These guidelines were classified in three categories: evidence based, consensus based and consensus based with no explicit consideration of evidence (CB-EB. Each guideline was evaluated by three of the authors using each of the instruments. For each guideline we assessed the agreement among 14 decision points which were selected from the NCCN (National Cancer Comprehensive Network guidelines algorithm. For each decision point we recorded the level of the quality of the information used to support it. A regression analysis was performed to assess if the percentage of high quality evidence used in the guidelines development was related to the overall quality of the guidelines. Results Three guidelines were classified as EB, three as CB-EB and two as CB. The EB guidelines scored better than CB, with the CB-EB scoring in the middle among all instruments for guidelines quality assessment. No major disagreement in recommendations was detected among the guidelines regardless of the method used for development, but the EB guidelines had a better agreement with the benchmark guideline for any decision point. When the source of evidence used to support decision were of high quality, we found a higher level of full agreement among the guidelines' recommendations. Up to 94% of variation in the quality score among guidelines could be explained by the quality of evidence used for guidelines development. Conclusion EB guidelines have a better quality than CB guidelines and CB-EB guidelines. Explicit use of high quality evidence

  3. Softcopy quality ruler method: implementation and validation

    Science.gov (United States)

    Jin, Elaine W.; Keelan, Brian W.; Chen, Junqing; Phillips, Jonathan B.; Chen, Ying

    2009-01-01

    A softcopy quality ruler method was implemented for the International Imaging Industry Association (I3A) Camera Phone Image Quality (CPIQ) Initiative. This work extends ISO 20462 Part 3 by virtue of creating reference digital images of known subjective image quality, complimenting the hardcopy Standard Reference Stimuli (SRS). The softcopy ruler method was developed using images from a Canon EOS 1Ds Mark II D-SLR digital still camera (DSC) and a Kodak P880 point-and-shoot DSC. Images were viewed on an Apple 30in Cinema Display at a viewing distance of 34 inches. Ruler images were made for 16 scenes. Thirty ruler images were generated for each scene, representing ISO 20462 Standard Quality Scale (SQS) values of approximately 2 to 31 at an increment of one just noticeable difference (JND) by adjusting the system modulation transfer function (MTF). A Matlab GUI was developed to display the ruler and test images side-by-side with a user-adjustable ruler level controlled by a slider. A validation study was performed at Kodak, Vista Point Technology, and Aptina Imaging in which all three companies set up a similar viewing lab to run the softcopy ruler method. The results show that the three sets of data are in reasonable agreement with each other, with the differences within the range expected from observer variability. Compared to previous implementations of the quality ruler, the slider-based user interface allows approximately 2x faster assessments with 21.6% better precision.

  4. Application Research of Ontology-enabled Process FMEA Knowledge Management Method

    Directory of Open Access Journals (Sweden)

    Zhao Xiuxu

    2012-04-01

    Full Text Available Failure Mode and Effect Analysis (FMEA is an important method to ensure the effectiveness of manufacturing process, which can prevent the happening of various potential failure. If the knowledge of FMEA can be accumulated and utilized reasonably, the quality management in manufacturing process will get decision support timely, and the efficiency of product quality problem analysis also can be improved. But, it is impossible to integrate the dispersive FMEA knowledge in the manufacturing process because there is a lack of unified management criterion of FMEA knowledge. In order to satisfy the requirement to share, reuse, and maintain FMEA knowledge, the representation method of FMEA knowledge based on ontology is put forward in this study. The structure of FMEA knowledge ontology can be described via visual modeling tool- Unified Modeling Language. In this study, the FMEA repository has been built and the acquisition, storage and searching of FMEA knowledge has been researched to satisfy the need of sharing and reusing of the FMEA knowledge in the manufacturing process.

  5. The Evaluation Methods of Decorative Concrete Horizontal Surfaces Quality

    Directory of Open Access Journals (Sweden)

    Albertas KLOVAS

    2013-09-01

    Full Text Available The main aim of this article was to determine blemishes of concrete surfaces and divide those surfaces according to following methods provided by two documents and by authors proposed image scanning method - “ImageJ”. The first method was CIB Report No. 24 “Tolerances on blemishes of concrete”. This method enables to evaluate concrete surfaces according to their visual appearance by using certain reference cards. The second method was GOST 13015.0-83. This method enables to evaluate the concrete surfaces according to their biggest dimension of the blemishes. The third, authors proposed, method was “ImageJ”. Latter method is based on the free source computer program. It helps to establish the quantity and the dimensions of the blemishes in the desired scale. Authors suggested to imply a ration between blemishes area and the all specimen’s area as a factor for evaluation of concrete surface quality. Three different concrete compositions were made: BA1, BA7 and BA8. Also, five different formworks were used: wood impregnated with polymeric oil [WPO], wood covered with rubber [WCR], sawn timber [ST], metal [M] and plastic [P] formworks. Following parameters of the obtained results were calculated: mean value, dispersion, standard deviation and the coefficient of variation. Also maximum and minimum values of experimental results are given. Intervals of the experimental results are provided for each specimen with the biggest possibility. DOI: http://dx.doi.org/10.5755/j01.ms.19.3.2006

  6. With 8D method to excellent quality

    Directory of Open Access Journals (Sweden)

    Marjanca Krajnc

    2012-10-01

    Full Text Available RQ: The research aims to establish the suitability of the 8D methodology for complaint settlement, and to identify any resulting improvement in quality.Purpose: Studies that have research the 8D method are scarce in international literature. Consequently, we decided to assess, based on theoretical premises, the suitability of the 8D method used by an organization, and the efficiency of quality performance directly associated with the 8D method. We will establish whether the use ofthe 8D method results in quality improvement.Method: The research will be carried out using qualitative analysis in the form of a case study of the 8D method used in an organization. I will discuss, based on real and relevant data, the approaches implemented by individual 8D method steps, indicating the integrated supplemental tools. In the quantitative part, I will identify the defective product trends (PPM and the trends of costs related to defective products.Results: The 8D method used for complaint settlement contributes to improved quality and company performance.Organization: The results can be used by the management in continuous improvement as additional motivation for more consistent and effective use, and for additional support to problem-solving coordinators and teams.Society: The findings can also be applied by society at large, mostly companies and public services.Originality: Research on this topic or combination has not yet been conductedLimitations: The sample studied is small, limited to one large company. It includes only the data obtained through the use of the 8D method.

  7. Methods for subjective determination of transmission quality

    CERN Document Server

    International Telecommunication Union. Geneva

    2000-01-01

    The main purpose of this List is to indicate all the ITU-T (and CCITT) Recommendations currently in effect at the date of its publication In addition, it includes the CCITT/ITU-T Supplements which contain operational or other practical/implementation a particular Series of Recommendations. At present, more than 2600 recommendations (standards) on some 60,000 pages are in force. Recommendations are non-binding standards agreed by consensus in technical study groups. ITU-T Recommendations are non-binding, however they are generally complied with due to their high quality and because they guarantee the interconnectivity of networks and enable telecommunication services to be provided on a worldwide scale.

  8. The quality of methods reporting in parasitology experiments.

    Science.gov (United States)

    Flórez-Vargas, Oscar; Bramhall, Michael; Noyes, Harry; Cruickshank, Sheena; Stevens, Robert; Brass, Andy

    2014-01-01

    There is a growing concern both inside and outside the scientific community over the lack of reproducibility of experiments. The depth and detail of reported methods are critical to the reproducibility of findings, but also for making it possible to compare and integrate data from different studies. In this study, we evaluated in detail the methods reporting in a comprehensive set of trypanosomiasis experiments that should enable valid reproduction, integration and comparison of research findings. We evaluated a subset of other parasitic (Leishmania, Toxoplasma, Plasmodium, Trichuris and Schistosoma) and non-parasitic (Mycobacterium) experimental infections in order to compare the quality of method reporting more generally. A systematic review using PubMed (2000-2012) of all publications describing gene expression in cells and animals infected with Trypanosoma spp was undertaken based on PRISMA guidelines; 23 papers were identified and included. We defined a checklist of essential parameters that should be reported and have scored the number of those parameters that are reported for each publication. Bibliometric parameters (impact factor, citations and h-index) were used to look for association between Journal and Author status and the quality of method reporting. Trichuriasis experiments achieved the highest scores and included the only paper to score 100% in all criteria. The mean of scores achieved by Trypanosoma articles through the checklist was 65.5% (range 32-90%). Bibliometric parameters were not correlated with the quality of method reporting (Spearman's rank correlation coefficient 0.05). Our results indicate that the quality of methods reporting in experimental parasitology is a cause for concern and it has not improved over time, despite there being evidence that most of the assessed parameters do influence the results. We propose that our set of parameters be used as guidelines to improve the quality of the reporting of experimental infection models

  9. The quality of methods reporting in parasitology experiments.

    Directory of Open Access Journals (Sweden)

    Oscar Flórez-Vargas

    Full Text Available There is a growing concern both inside and outside the scientific community over the lack of reproducibility of experiments. The depth and detail of reported methods are critical to the reproducibility of findings, but also for making it possible to compare and integrate data from different studies. In this study, we evaluated in detail the methods reporting in a comprehensive set of trypanosomiasis experiments that should enable valid reproduction, integration and comparison of research findings. We evaluated a subset of other parasitic (Leishmania, Toxoplasma, Plasmodium, Trichuris and Schistosoma and non-parasitic (Mycobacterium experimental infections in order to compare the quality of method reporting more generally. A systematic review using PubMed (2000-2012 of all publications describing gene expression in cells and animals infected with Trypanosoma spp was undertaken based on PRISMA guidelines; 23 papers were identified and included. We defined a checklist of essential parameters that should be reported and have scored the number of those parameters that are reported for each publication. Bibliometric parameters (impact factor, citations and h-index were used to look for association between Journal and Author status and the quality of method reporting. Trichuriasis experiments achieved the highest scores and included the only paper to score 100% in all criteria. The mean of scores achieved by Trypanosoma articles through the checklist was 65.5% (range 32-90%. Bibliometric parameters were not correlated with the quality of method reporting (Spearman's rank correlation coefficient 0.05. Our results indicate that the quality of methods reporting in experimental parasitology is a cause for concern and it has not improved over time, despite there being evidence that most of the assessed parameters do influence the results. We propose that our set of parameters be used as guidelines to improve the quality of the reporting of experimental

  10. Using statistical methods of quality management in logistics processes

    Directory of Open Access Journals (Sweden)

    Tkachenko Alla

    2016-04-01

    Full Text Available The purpose of the paper is to study the application of statistical methods of logistics process quality management at a large industrial enterprise and testing the theoretical studies. The analysis of the publications shows that a significant number of works by both Ukrainian and foreign authors has been dedicated to the research of quality management, while statistical methods of quality management have only been thoroughly analyzed by a small number of researchers, since these methods are referred to as classical, that is, those that are considered well-known and do not require special attention of modern scholars. In the authors’ opinion, the logistics process is a process of transformation and movement of material and accompanying flows by ensuring management freedom under the conditions of sequential interdependencies; standardization; synchronization; sharing information, and consistency of incentives, using innovative methods and models. In our study, we have shown that the management of logistics processes should use such statistical methods of quality management as descriptive statistics, experiment planning, hypotheses testing, measurement analysis, process opportunities analysis, regression analysis, reliability analysis, sampling, modeling, maps of statistical process control, specification of statistical tolerance, time series analysis. The proposed statistical methods of logistics processes quality management have been tested at the large industrial enterprise JSC "Dniepropetrovsk Aggregate Plant" that specializes in manufacturing hydraulic control valves. The findings suggest that the main purpose in the sphere of logistics processes quality is the continuous improvement of the mining equipment production quality through the use of innovative processes, advanced management systems and information technology. This will enable the enterprise to meet the requirements and expectations of their customers. It has been proved that the

  11. Web-enabled video-feedback: a method to reflect on the communication skills of experienced physicians.

    NARCIS (Netherlands)

    Noordman, J.; Verhaak, P.; Dulmen, S. van

    2011-01-01

    OBJECTIVE: To describe our web-enabled video-feedback method designed to reflect on the communication skills of experienced physicians. METHODS: Participating physicians (n=28) received a 'personal web link' to two of their video-recorded consultations. After watching the consultations physicians re

  12. Web-enabled video-feedback: a method to reflect on the communication skills of experienced physicians.

    NARCIS (Netherlands)

    Noordman, J.; Verhaak, P.; Dulmen, S. van

    2011-01-01

    OBJECTIVE: To describe our web-enabled video-feedback method designed to reflect on the communication skills of experienced physicians. METHODS: Participating physicians (n=28) received a 'personal web link' to two of their video-recorded consultations. After watching the consultations physicians

  13. A Viewpoint on Wearable Technology-Enabled Measurement of Wellbeing and Health-Related Quality of Life in Parkinson’s Disease

    Science.gov (United States)

    van Uem, Janet M.T.; Isaacs, Tom; Lewin, Alan; Bresolin, Eros; Salkovic, Dina; Espay, Alberto J.; Matthews, Helen; Maetzler, Walter

    2016-01-01

    In this viewpoint, we discuss how several aspects of Parkinson’s disease (PD) – known to be correlated with wellbeing and health-related quality of life–could be measured using wearable devices (‘wearables’). Moreover, three people with PD (PwP) having exhaustive experience with using such devices write about their personal understanding of wellbeing and health-related quality of life, building a bridge between the true needs defined by PwP and the available methods of data collection. Rapidly evolving new technologies develop wearables that probe function and behaviour in domestic environments of people with chronic conditions such as PD and have the potential to serve their needs. Gathered data can serve to inform patient-driven management changes, enabling greater control by PwP and enhancing likelihood of improvements in wellbeing and health-related quality of life. Data can also be used to quantify wellbeing and health-related quality of life. Additionally these techniques can uncover novel more sensitive and more ecologically valid disease-related endpoints. Active involvement of PwP in data collection and interpretation stands to provide personally and clinically meaningful endpoints and milestones to inform advances in research and relevance of translational efforts in PD. PMID:27003779

  14. Rational, computer-enabled peptide drug design: principles, methods, applications and future directions.

    Science.gov (United States)

    Diller, David J; Swanson, Jon; Bayden, Alexander S; Jarosinski, Mark; Audie, Joseph

    2015-01-01

    Peptides provide promising templates for developing drugs to occupy a middle space between small molecules and antibodies and for targeting 'undruggable' intracellular protein-protein interactions. Importantly, rational or in cerebro design, especially when coupled with validated in silico tools, can be used to efficiently explore chemical space and identify islands of 'drug-like' peptides to satisfy diverse drug discovery program objectives. Here, we consider the underlying principles of and recent advances in rational, computer-enabled peptide drug design. In particular, we consider the impact of basic physicochemical properties, potency and ADME/Tox opportunities and challenges, and recently developed computational tools for enabling rational peptide drug design. Key principles and practices are spotlighted by recent case studies. We close with a hypothetical future case study.

  15. [The method of quality function deployment --QFD-- in nursing services planning].

    Science.gov (United States)

    Matsuda, L M; Evora, Y D; Boan, F S

    2000-10-01

    "Focus on the client" is the posture that must be adopted in order to offer quality products. Based on the Total Quality Management approach, the Quality Function Deployment method (QFD) is a tool to achieve this goal. The purpose of this study is to create a proposal for planning the nursing services following the steps and actions of this methodology. The basic procedure was to survey the necessity of 106 hospitalized patients. Data were deployed using the seventeen steps proposed. Results showed that the interaction is more important than the technique according to the clients and also that this method enables the implementation of quality in nursing care.

  16. Impact of nursing care in Australian general practice on the quality of care: A pilot of the Patient Enablement and Satisfaction Survey (PESS)

    NARCIS (Netherlands)

    Desborough, J.; Phillips, C.; Banfield, M.; Bagheri, N.; Mills, J.

    2015-01-01

    BACKGROUND: Nursing roles in general practice have undergone significant expansion, but as yet there are few tools to measure the quality of nursing care in general practice. This study piloted the Patient Enablement and Satisfaction Survey (PESS) to evaluate two aspects of quality of care in this s

  17. [Methodology, method, and quality of qualitative research].

    Science.gov (United States)

    Frommer, Jörg; Rennie, David L

    2006-05-01

    Over the last ten years qualitative research approaches have been increasingly recognized and applied to the fields of psychotherapy and psychosomatic medicine in German-speaking countries, although this development has lagged behind what has occurred at the same time in English-speaking countries. In the former, especially, a misunderstanding prevails that qualitative research methods are at best preliminary to real science. This misunderstanding has roots in the philosophy of science and the sociology of knowledge. It comes from the lack of recognition that the human sciences, unlike the natural sciences, entail a double rather than single hermeneutic and that qualitative research methods are logically coherent ways of working systematically and rigorously with this double hermeneutic. Indeed, this nature of qualitative research is generally not well understood by many qualitative researchers themselves. In this article, the need for qualitative research is shown and its methodology is seen as an integration of method and hermeneutics, or methodical hermeneutics, which in turn is distinguished from alternative qualitative research methodologies. The article closes with considerations of quality criteria and publication standards.

  18. Method for synthesis of high quality graphene

    Science.gov (United States)

    Lanzara, Alessandra [Piedmont, CA; Schmid, Andreas K [Berkeley, CA; Yu, Xiaozhu [Berkeley, CA; Hwang, Choonkyu [Albany, CA; Kohl, Annemarie [Beneditkbeuern, DE; Jozwiak, Chris M [Oakland, CA

    2012-03-27

    A method is described herein for the providing of high quality graphene layers on silicon carbide wafers in a thermal process. With two wafers facing each other in close proximity, in a first vacuum heating stage, while maintained at a vacuum of around 10.sup.-6 Torr, the wafer temperature is raised to about 1500.degree. C., whereby silicon evaporates from the wafer leaving a carbon rich surface, the evaporated silicon trapped in the gap between the wafers, such that the higher vapor pressure of silicon above each of the wafers suppresses further silicon evaporation. As the temperature of the wafers is raised to about 1530.degree. C. or more, the carbon atoms self assemble themselves into graphene.

  19. Development of undisturbed sampling method enabling visual observation; Mokushi kanona fukakuran shiryo saishuho no kaihatsu

    Energy Technology Data Exchange (ETDEWEB)

    Asano, I. [Kansai Electric Power Co. Inc., Kyoto (Japan)

    1999-11-10

    A jig was developed for sampling falus sediment, weathered soft rock, conglomerate soil, etc. The jig is characterized by the capability of sampling in an undisturbed state, direct visual observation of collected samples, and the sampling up to 10m in depth. Explained below are the improved points of the jig. The recessed shape at the tip end of a diamond bit was shaped in a semi-circular groove for the purpose of preventing the collected samples from being disturbed by water from a drilled hole. The outer tube, rod and casing pipe were made of Al alloy and, therefore, half as heavy as the conventional components. The material of the inner tube was designed to have two kinds, acrylic and polyester, so that the samples were directly visually observed on site. Evaluations were conducted in verification tests at the original positions. Provision of notches in the diamond bit enabled the application to all grounds. The acrylic inner tube was superior in a weathered sand soil. The polyester inner tube was found excellent in impact resistance. The sampling depth increased by making the drilling tool lightweight and improving the hole maintenance measures. Undisturbed sampling proved possible. (NEDO)

  20. Facile method of building hydroxyapatite 3D scaffolds assembled from porous hollow fibers enabling nutrient delivery

    NARCIS (Netherlands)

    Salamon, David; Da Silva Teixeira, Sandra; Dutczak, S.M.; Stamatialis, Dimitrios

    2014-01-01

    Nowadays, diffusion through scaffold and tissue usually limits transport, and forms potentially hypoxic regions. Several methods are used for preparation of 3D hydroxyapatite scaffolds, however, production of a scaffold including porous hollow fibers for nutrition delivery is difficult and

  1. General Quality Control (QC) Guidelines for SAM Methods

    Science.gov (United States)

    Learn more about quality control guidelines and recommendations for the analysis of samples using the methods listed in EPA's Selected Analytical Methods for Environmental Remediation and Recovery (SAM).

  2. Iodine absorption cells quality evaluation methods

    Science.gov (United States)

    Hrabina, Jan; Zucco, Massimo; Holá, Miroslava; Šarbort, Martin; Acef, Ouali; Du-Burck, Frédéric; Lazar, Josef; Číp, Ondřej

    2016-12-01

    The absorption cells represent an unique tool for the laser frequency stabilization. They serve as irreplaceable optical frequency references in realization of high-stable laser standards and laser sources for different brands of optical measurements, including the most precise frequency and dimensional measurement systems. One of the most often used absorption media covering visible and near IR spectral range is molecular iodine. It offers rich atlas of very strong and narrow spectral transitions which allow realization of laser systems with ultimate frequency stabilities in or below 10-14 order level. One of the most often disccussed disadvantage of the iodine cells is iodine's corrosivity and sensitivity to presence of foreign substances. The impurities react with absorption media and cause spectral shifts of absorption spectra, spectral broadening of the transitions and decrease achievable signal-to-noise ratio of the detected spectra. All of these unwanted effects directly influence frequency stability of the realized laser standard and due to this fact, the quality of iodine cells must be precisely controlled. We present a comparison of traditionally used method of laser induced fluorescence (LIF) with novel technique based on hyperfine transitions linewidths measurement. The results summarize advantages and drawbacks of these techniques and give a recommendation for their practical usage.

  3. Facial masculinity: how the choice of measurement method enables to detect its influence on behaviour.

    Science.gov (United States)

    Sanchez-Pages, Santiago; Rodriguez-Ruiz, Claudia; Turiegano, Enrique

    2014-01-01

    Recent research has explored the relationship between facial masculinity, human male behaviour and males' perceived features (i.e. attractiveness). The methods of measurement of facial masculinity employed in the literature are quite diverse. In the present paper, we use several methods of measuring facial masculinity to study the effect of this feature on risk attitudes and trustworthiness. We employ two strategic interactions to measure these two traits, a first-price auction and a trust game. We find that facial width-to-height ratio is the best predictor of trustworthiness, and that measures of masculinity which use Geometric Morphometrics are the best suited to link masculinity and bidding behaviour. However, we observe that the link between masculinity and bidding in the first-price auction might be driven by competitiveness and not by risk aversion only. Finally, we test the relationship between facial measures of masculinity and perceived masculinity. As a conclusion, we suggest that researchers in the field should measure masculinity using one of these methods in order to obtain comparable results. We also encourage researchers to revise the existing literature on this topic following these measurement methods.

  4. A Simple Method Enabling Students to Model Impact Cratering from 0° to 90°.

    Science.gov (United States)

    Burgener, J. A.

    2016-08-01

    A simple, inexpensive method to produce craters with impact angles ranging from 0° to 90° is presented. It utilizes low speed pellet guns and soft clay. Varying the hardness of the clay and speed of the pellets allows a wide range of experiments.

  5. Facial Masculinity: How the Choice of Measurement Method Enables to Detect Its Influence on Behaviour

    Science.gov (United States)

    Sanchez-Pages, Santiago; Rodriguez-Ruiz, Claudia; Turiegano, Enrique

    2014-01-01

    Recent research has explored the relationship between facial masculinity, human male behaviour and males' perceived features (i.e. attractiveness). The methods of measurement of facial masculinity employed in the literature are quite diverse. In the present paper, we use several methods of measuring facial masculinity to study the effect of this feature on risk attitudes and trustworthiness. We employ two strategic interactions to measure these two traits, a first-price auction and a trust game. We find that facial width-to-height ratio is the best predictor of trustworthiness, and that measures of masculinity which use Geometric Morphometrics are the best suited to link masculinity and bidding behaviour. However, we observe that the link between masculinity and bidding in the first-price auction might be driven by competitiveness and not by risk aversion only. Finally, we test the relationship between facial measures of masculinity and perceived masculinity. As a conclusion, we suggest that researchers in the field should measure masculinity using one of these methods in order to obtain comparable results. We also encourage researchers to revise the existing literature on this topic following these measurement methods. PMID:25389770

  6. Exact kinetic energy enables accurate evaluation of weak interactions by the FDE-vdW method.

    Science.gov (United States)

    Sinha, Debalina; Pavanello, Michele

    2015-08-28

    The correlation energy of interaction is an elusive and sought-after interaction between molecular systems. By partitioning the response function of the system into subsystem contributions, the Frozen Density Embedding (FDE)-vdW method provides a computationally amenable nonlocal correlation functional based on the adiabatic connection fluctuation dissipation theorem applied to subsystem density functional theory. In reproducing potential energy surfaces of weakly interacting dimers, we show that FDE-vdW, either employing semilocal or exact nonadditive kinetic energy functionals, is in quantitative agreement with high-accuracy coupled cluster calculations (overall mean unsigned error of 0.5 kcal/mol). When employing the exact kinetic energy (which we term the Kohn-Sham (KS)-vdW method), the binding energies are generally closer to the benchmark, and the energy surfaces are also smoother.

  7. Exact kinetic energy enables accurate evaluation of weak interactions by the FDE-vdW method

    Energy Technology Data Exchange (ETDEWEB)

    Sinha, Debalina; Pavanello, Michele, E-mail: m.pavanello@rutgers.edu [Department of Chemistry, Rutgers University, Newark, New Jersey 07102 (United States)

    2015-08-28

    The correlation energy of interaction is an elusive and sought-after interaction between molecular systems. By partitioning the response function of the system into subsystem contributions, the Frozen Density Embedding (FDE)-vdW method provides a computationally amenable nonlocal correlation functional based on the adiabatic connection fluctuation dissipation theorem applied to subsystem density functional theory. In reproducing potential energy surfaces of weakly interacting dimers, we show that FDE-vdW, either employing semilocal or exact nonadditive kinetic energy functionals, is in quantitative agreement with high-accuracy coupled cluster calculations (overall mean unsigned error of 0.5 kcal/mol). When employing the exact kinetic energy (which we term the Kohn-Sham (KS)-vdW method), the binding energies are generally closer to the benchmark, and the energy surfaces are also smoother.

  8. Clipping and Coding Audio Files: A Research Method to Enable Participant Voice

    Directory of Open Access Journals (Sweden)

    Susan Crichton

    2005-09-01

    Full Text Available Qualitative researchers have long used ethnographic methods to make sense of complex human activities and experiences. Their blessing is that through them, researchers can collect a wealth of raw data. Their challenge is that they require the researcher to find patterns and organize the various themes and concepts that emerge during the analysis stage into a coherent narrative that a reader can follow. In this article, the authors introduce a technology-enhanced data collection and analysis method based on clipped audio files. They suggest not only that the use of appropriate software and hardware can help in this process but, in fact, that their use can honor the participants' voices, retaining the original three-dimensional recording well past the data collection stage.

  9. Novel Methods for Activity Classification and Occupany Prediction Enabling Fine-grained HVAC Control

    OpenAIRE

    Rana, Rajib; Kusy, Brano; Wall, Josh; Hu, Wen

    2014-01-01

    Much of the energy consumption in buildings is due to HVAC systems, which has motivated several recent studies on making these systems more energy- efficient. Occupancy and activity are two important aspects, which need to be correctly estimated for optimal HVAC control. However, state-of-the-art methods to estimate occupancy and classify activity require infrastructure and/or wearable sensors which suffers from lower acceptability due to higher cost. Encouragingly, with the advancement of th...

  10. Highly Efficient Perovskite Nanocrystal Light-Emitting Diodes Enabled by a Universal Crosslinking Method.

    Science.gov (United States)

    Li, Guangru; Rivarola, Florencia Wisnivesky Rocca; Davis, Nathaniel J L K; Bai, Sai; Jellicoe, Tom C; de la Peña, Francisco; Hou, Shaocong; Ducati, Caterina; Gao, Feng; Friend, Richard H; Greenham, Neil C; Tan, Zhi-Kuang

    2016-05-01

    The preparation of highly efficient perovskite nanocrystal light-emitting diodes is shown. A new trimethylaluminum vapor-based crosslinking method to render the nanocrystal films insoluble is applied. The resulting near-complete nanocrystal film coverage, coupled with the natural confinement of injected charges within the perovskite crystals, facilitates electron-hole capture and give rise to a remarkable electroluminescence yield of 5.7%.

  11. Enabling Advanced Wind-Tunnel Research Methods Using the NASA Langley 12-Foot Low Speed Tunnel

    Science.gov (United States)

    Busan, Ronald C.; Rothhaar, Paul M.; Croom, Mark A.; Murphy, Patrick C.; Grafton, Sue B.; O-Neal, Anthony W.

    2014-01-01

    Design of Experiment (DOE) testing methods were used to gather wind tunnel data characterizing the aerodynamic and propulsion forces and moments acting on a complex vehicle configuration with 10 motor-driven propellers, 9 control surfaces, a tilt wing, and a tilt tail. This paper describes the potential benefits and practical implications of using DOE methods for wind tunnel testing - with an emphasis on describing how it can affect model hardware, facility hardware, and software for control and data acquisition. With up to 23 independent variables (19 model and 2 tunnel) for some vehicle configurations, this recent test also provides an excellent example of using DOE methods to assess critical coupling effects in a reasonable timeframe for complex vehicle configurations. Results for an exploratory test using conventional angle of attack sweeps to assess aerodynamic hysteresis is summarized, and DOE results are presented for an exploratory test used to set the data sampling time for the overall test. DOE results are also shown for one production test characterizing normal force in the Cruise mode for the vehicle.

  12. Method of Separating Oxygen From Spacecraft Cabin Air to Enable Extravehicular Activities

    Science.gov (United States)

    Graf, John C.

    2013-01-01

    Extravehicular activities (EVAs) require high-pressure, high-purity oxygen. Shuttle EVAs use oxygen that is stored and transported as a cryogenic fluid. EVAs on the International Space Station (ISS) presently use the Shuttle cryo O2, which is transported to the ISS using a transfer hose. The fluid is compressed to elevated pressures and stored as a high-pressure gas. With the retirement of the shuttle, NASA has been searching for ways to deliver oxygen to fill the highpressure oxygen tanks on the ISS. A method was developed using low-pressure oxygen generated onboard the ISS and released into ISS cabin air, filtering the oxygen from ISS cabin air using a pressure swing absorber to generate a low-pressure (high-purity) oxygen stream, compressing the oxygen with a mechanical compressor, and transferring the high-pressure, high-purity oxygen to ISS storage tanks. The pressure swing absorber (PSA) can be either a two-stage device, or a single-stage device, depending on the type of sorbent used. The key is to produce a stream with oxygen purity greater than 99.5 percent. The separator can be a PSA device, or a VPSA device (that uses both vacuum and pressure for the gas separation). The compressor is a multi-stage mechanical compressor. If the gas flow rates are on the order of 5 to 10 lb (.2.3 to 4.6 kg) per day, the compressor can be relatively small [3 16 16 in. (.8 41 41 cm)]. Any spacecraft system, or other remote location that has a supply of lowpressure oxygen, a method of separating oxygen from cabin air, and a method of compressing the enriched oxygen stream, has the possibility of having a regenerable supply of highpressure, high-purity oxygen that is compact, simple, and safe. If cabin air is modified so there is very little argon, the separator can be smaller, simpler, and use less power.

  13. A processing method enabling the use of peak height for accurate and precise proton NMR quantitation.

    Science.gov (United States)

    Hays, Patrick A; Thompson, Robert A

    2009-10-01

    In NMR, peak area quantitation is the most common method used because the area under a peak or peak group is proportional to the number of nuclei at those frequencies. Peak height quantitation has not enjoyed as much utility because of poor precision and linearity as a result of inconsistent shapes and peak widths (measured at half height). By using a post-acquisition processing method employing a Gaussian or line-broadening (exponential decay) apodization (i.e. weighting function) to normalize the shape and width of the internal standard (ISTD) peak, the heights of an analyte calibration spectrum can be compared to the analyte peaks in a sample spectrum resulting in accurate and precise quantitative results. Peak height results compared favorably with 'clean' peak area results for several hundred illicit samples of methamphetamine HCl, cocaine HCl, and heroin HCl, of varying composition and purity. Using peak height and peak area results together can enhance the confidence in the reported purity value; a major advantage in high throughput, automated quantitative analyses. Published in 2009 by John Wiley & Sons, Ltd.

  14. IMPROVEMENT OF QUALITY IN PRODUCTION PROCESS BY APPLYING KAIKAKU METHOD

    Directory of Open Access Journals (Sweden)

    Milan Radenkovic

    2013-12-01

    Full Text Available In this paper, Kaikaku method is presented. The essence of this method is introduction, principles and ways of implementation in the real systems. The main point how Kaikaku method influences on quality. It is presented on the practical example (furniture industry, one way how to implement Kaikaku method and how influence on quality improvement of production process.

  15. IT-enabled Quality Management implementations in Small Healthcare Institutions: Method and Case Study

    NARCIS (Netherlands)

    Smit, Koen; Mens, Joris; Versendaal, Johan; Sewberath Misser, Navin; Ravesteijn, Pascal

    2013-01-01

    In the dynamic environment of increasing regulations, increasing patient demand, decentralization of budgets and enforcement of efficiency, small sized healthcare institutions in the Netherlands are having a difficult time. Although these service providers are usually capable of flexibly delivering

  16. Machine learning methods enable predictive modeling of antibody feature:function relationships in RV144 vaccinees.

    Directory of Open Access Journals (Sweden)

    Ickwon Choi

    2015-04-01

    Full Text Available The adaptive immune response to vaccination or infection can lead to the production of specific antibodies to neutralize the pathogen or recruit innate immune effector cells for help. The non-neutralizing role of antibodies in stimulating effector cell responses may have been a key mechanism of the protection observed in the RV144 HIV vaccine trial. In an extensive investigation of a rich set of data collected from RV144 vaccine recipients, we here employ machine learning methods to identify and model associations between antibody features (IgG subclass and antigen specificity and effector function activities (antibody dependent cellular phagocytosis, cellular cytotoxicity, and cytokine release. We demonstrate via cross-validation that classification and regression approaches can effectively use the antibody features to robustly predict qualitative and quantitative functional outcomes. This integration of antibody feature and function data within a machine learning framework provides a new, objective approach to discovering and assessing multivariate immune correlates.

  17. Enabling Context-Aware Computing for the Nomadic Mobile User: A Service Oriented and Quality Driven Approach

    NARCIS (Netherlands)

    Pawar, Pravin; Halteren, van Aart; Sheikh, Kamran

    2007-01-01

    Context-awareness (CA) enables the development of personalized applications for highly mobile and demanding users in the pervasive environments. These applications rely on the components responsible for context sensing, processing, storage and inference. Various context-aware computing infrastructur

  18. Theoretical and methodical support of calculating expenses for quality

    OpenAIRE

    Пархоменко, Валерій Миколайович

    2015-01-01

    A hybrid models of calculating expenses for quality on the full life cycle in combination with types of expenses on purpose and model of goods costing considering expenses for quality by standard-functional method have been developed.

  19. Surface water quality assessment by environmetric methods.

    Science.gov (United States)

    Boyacioglu, Hülya; Boyacioglu, Hayal

    2007-08-01

    This environmetric study deals with the interpretation of river water monitoring data from the basin of the Buyuk Menderes River and its tributaries in Turkey. Eleven variables were measured to estimate water quality at 17 sampling sites. Factor analysis was applied to explain the correlations between the observations in terms of underlying factors. Results revealed that, water quality was strongly affected from agricultural uses. Cluster analysis was used to classify stations with similar properties and results distinguished three groups of stations. Water quality at downstream of the river was quite different from the other part. It is recommended to involve the environmetric data treatment as a substantial procedure in assessment of water quality data.

  20. Macron Formed Liner Compression as a Practical Method for Enabling Magneto-Inertial Fusion

    Energy Technology Data Exchange (ETDEWEB)

    Slough, John

    2011-12-10

    The entry of fusion as a viable, competitive source of power has been stymied by the challenge of finding an economical way to provide for the confinement and heating of the plasma fuel. The main impediment for current nuclear fusion concepts is the complexity and large mass associated with the confinement systems. To take advantage of the smaller scale, higher density regime of magnetic fusion, an efficient method for achieving the compressional heating required to reach fusion gain conditions must be found. The very compact, high energy density plasmoid commonly referred to as a Field Reversed Configuration (FRC) provides for an ideal target for this purpose. To make fusion with the FRC practical, an efficient method for repetitively compressing the FRC to fusion gain conditions is required. A novel approach to be explored in this endeavor is to remotely launch a converging array of small macro-particles (macrons) that merge and form a more massive liner inside the reactor which then radially compresses and heats the FRC plasmoid to fusion conditions. The closed magnetic field in the target FRC plasmoid suppresses the thermal transport to the confining liner significantly lowering the imploding power needed to compress the target. With the momentum flux being delivered by an assemblage of low mass, but high velocity macrons, many of the difficulties encountered with the liner implosion power technology are eliminated. The undertaking to be described in this proposal is to evaluate the feasibility achieving fusion conditions from this simple and low cost approach to fusion. During phase I the design and testing of the key components for the creation of the macron formed liner have been successfully carried out. Detailed numerical calculations of the merging, formation and radial implosion of the Macron Formed Liner (MFL) were also performed. The phase II effort will focus on an experimental demonstration of the macron launcher at full power, and the demonstration

  1. Novel selective TOCSY method enables NMR spectral elucidation of metabolomic mixtures

    Science.gov (United States)

    MacKinnon, Neil; While, Peter T.; Korvink, Jan G.

    2016-11-01

    Complex mixture analysis is routinely encountered in NMR-based investigations. With the aim of component identification, spectral complexity may be addressed chromatographically or spectroscopically, the latter being favored to reduce sample handling requirements. An attractive experiment is selective total correlation spectroscopy (sel-TOCSY), which is capable of providing tremendous spectral simplification and thereby enhancing assignment capability. Unfortunately, isolating a well resolved resonance is increasingly difficult as the complexity of the mixture increases and the assumption of single spin system excitation is no longer robust. We present TOCSY optimized mixture elucidation (TOOMIXED), a technique capable of performing spectral assignment particularly in the case where the assumption of single spin system excitation is relaxed. Key to the technique is the collection of a series of 1D sel-TOCSY experiments as a function of the isotropic mixing time (τm), resulting in a series of resonance intensities indicative of the underlying molecular structure. By comparing these τm -dependent intensity patterns with a library of pre-determined component spectra, one is able to regain assignment capability. After consideration of the technique's robustness, we tested TOOMIXED firstly on a model mixture. As a benchmark we were able to assign a molecule with high confidence in the case of selectively exciting an isolated resonance. Assignment confidence was not compromised when performing TOOMIXED on a resonance known to contain multiple overlapping signals, and in the worst case the method suggested a follow-up sel-TOCSY experiment to confirm an ambiguous assignment. TOOMIXED was then demonstrated on two realistic samples (whisky and urine), where under our conditions an approximate limit of detection of 0.6 mM was determined. Taking into account literature reports for the sel-TOCSY limit of detection, the technique should reach on the order of 10 μ M

  2. Oil Products Quality Improvement by Adsorption Method

    Directory of Open Access Journals (Sweden)

    Kulash K. Syrmanova

    2017-02-01

    Full Text Available Petroleum takes the leading place in fuel and energy sector. It is a basis of fuel and energy balance of advanced countries economics. Light oil proven reserves reducing is a general trend of modern oil industry development. Almost the entire increase in reserves is due to viscous heavy sour oil [1-2]. Nowadays quality of the most important oil products is a crucial problem in refinery industry. The problem of oil products quality is connected with their using and operation in engines and machines. Requirements increasing to stability and effective technics maintenance leads to oil products running abilities significant hardening. In order to protect the environment, the task to obtain oil products with improved environmental properties was assigned. Properties of the oil determine the direction and condition of its processing and directly affect the quality of the oil products [3-4].

  3. Quality Index Method - An objective tool for determination of sensory quality

    DEFF Research Database (Denmark)

    Hyldig, Grethe; Green-Petersen, Ditte

    2004-01-01

    seen as a subjective assessment of quality. However, sensory methods can be turned into an objective tool. European fisheries research institutes have developed such a tool, by which sensory assessment is performed in a systematic way with an objective quality assessment method called the Quality Index...

  4. A Simple Flow-Cytometric Method Measuring B Cell Surface Immunoglobulin Avidity Enables Characterization of Affinity Maturation to Influenza A Virus

    Science.gov (United States)

    Frank, Gregory M.; Ince, William L.; Gibbs, James S.; Khurana, Surender; Wheatley, Adam K.; Max, Edward E.; McDermott, Adrian B.; Golding, Hana; Stevens, James; Bennink, Jack R.

    2015-01-01

    ABSTRACT Antibody (Ab) affinity maturation enables an individual to maintain immunity to an increasing number of pathogens within the limits of a total Ig production threshold. A better understanding of this process is critical for designing vaccines that generate optimal Ab responses to pathogens. Our study describes a simple flow-cytometric method that enumerates virus-specific germinal center (GC) B cells as well as their AC50, a measure of Ab avidity, defined as the antigen concentration required to detect 50% of specific B cells. Using a model of mouse Ab responses to the influenza A virus hemagglutinin (IAV HA), we obtained data indicating that AC50 decreases with time postinfection in an affinity maturation-dependent process. As proof of principle of the utility of the method, our data clearly show that relative to intranasal IAV infection, intramuscular immunization against inactivated IAV in adjuvant results in a diminished GC HA B cell response, with increased AC50 correlating with an increased serum Ab off-rate. Enabling simultaneous interrogation of both GC HA B cell quantity and quality, this technique should facilitate study of affinity maturation and rational vaccine design. PMID:26242629

  5. Subspecialty surgical pathologist′s performances as triage pathologists on a telepathology-enabled quality assurance surgical pathology service: A human factors study

    Directory of Open Access Journals (Sweden)

    Beth L. Braunhut

    2014-01-01

    Full Text Available Background: The case triage practice workflow model was used to manage incoming cases on a telepathology-enabled surgical pathology quality assurance (QA service. Maximizing efficiency of workflow and the use of pathologist time requires detailed information on factors that influence telepathologists′ decision-making on a surgical pathology QA service, which was gathered and analyzed in this study. Materials and Methods: Surgical pathology report reviews and telepathology service logs were audited, for 1862 consecutive telepathology QA cases accrued from a single Arizona rural hospital over a 51 month period. Ten university faculty telepathologists served as the case readers. Each telepathologist had an area of subspecialty surgical pathology expertise (i.e. gastrointestinal pathology, dermatopathology, etc. but functioned largely as a general surgical pathologist while on this telepathology-enabled QA service. They handled all incoming cases during their individual 1-h telepathology sessions, regardless of the nature of the organ systems represented in the real-time incoming stream of outside surgical pathology cases. Results: The 10 participating telepathologists′ postAmerican Board of pathology examination experience ranged from 3 to 36 years. This is a surrogate for age. About 91% of incoming cases were immediately signed out regardless of the subspecialty surgical pathologists′ area of surgical pathology expertise. One hundred and seventy cases (9.13% were deferred. Case concurrence rates with the provisional surgical pathology diagnosis of the referring pathologist, for incoming cases, averaged 94.3%, but ranged from 88.46% to 100% for individual telepathologists. Telepathology case deferral rates, for second opinions or immunohistochemistry, ranged from 4.79% to 21.26%. Differences in concordance rates and deferral rates among telepathologists, for incoming cases, were significant but did not correlate with years of experience as a

  6. Analyzing of coffee quality with different methods

    Directory of Open Access Journals (Sweden)

    Rajković Miloš B.

    2004-01-01

    Full Text Available The results obtained by the analysis of the samples of coffee mostly consumed on our market showed that the coffee quality corresponds to the values as given in the Law of Health Food. It was not found that any of the parameters which determine food quality exceeded permitted values. Content of heavy metals and aflatoxines is below permitted values. The least content of caffeine was determined in a coffee sample roasted in the private roaster’s shop, and only in it the presence of coffee surrogates/substitutes was not proved. The obtained results of the coffee analysis showed that the coffees of most popular producers are very equal, and results of caffeine analysis are even more equal. This indicates the most probable fact that coffee is of the same origin, and that later, on during production, a different mixture was made, which affects the final product and gives aroma and taste to the liquid.

  7. Low-Cost 3D Printers Enable High-Quality and Automated Sample Preparation and Molecular Detection.

    Science.gov (United States)

    Chan, Kamfai; Coen, Mauricio; Hardick, Justin; Gaydos, Charlotte A; Wong, Kah-Yat; Smith, Clayton; Wilson, Scott A; Vayugundla, Siva Praneeth; Wong, Season

    2016-01-01

    Most molecular diagnostic assays require upfront sample preparation steps to isolate the target's nucleic acids, followed by its amplification and detection using various nucleic acid amplification techniques. Because molecular diagnostic methods are generally rather difficult to perform manually without highly trained users, automated and integrated systems are highly desirable but too costly for use at point-of-care or low-resource settings. Here, we showcase the development of a low-cost and rapid nucleic acid isolation and amplification platform by modifying entry-level 3D printers that cost between $400 and $750. Our modifications consisted of replacing the extruder with a tip-comb attachment that houses magnets to conduct magnetic particle-based nucleic acid extraction. We then programmed the 3D printer to conduct motions that can perform high-quality extraction protocols. Up to 12 samples can be processed simultaneously in under 13 minutes and the efficiency of nucleic acid isolation matches well against gold-standard spin-column-based extraction technology. Additionally, we used the 3D printer's heated bed to supply heat to perform water bath-based polymerase chain reactions (PCRs). Using another attachment to hold PCR tubes, the 3D printer was programmed to automate the process of shuttling PCR tubes between water baths. By eliminating the temperature ramping needed in most commercial thermal cyclers, the run time of a 35-cycle PCR protocol was shortened by 33%. This article demonstrates that for applications in resource-limited settings, expensive nucleic acid extraction devices and thermal cyclers that are used in many central laboratories can be potentially replaced by a device modified from inexpensive entry-level 3D printers.

  8. Low-Cost 3D Printers Enable High-Quality and Automated Sample Preparation and Molecular Detection

    Science.gov (United States)

    Chan, Kamfai; Coen, Mauricio; Hardick, Justin; Gaydos, Charlotte A.; Wong, Kah-Yat; Smith, Clayton; Wilson, Scott A.; Vayugundla, Siva Praneeth; Wong, Season

    2016-01-01

    Most molecular diagnostic assays require upfront sample preparation steps to isolate the target’s nucleic acids, followed by its amplification and detection using various nucleic acid amplification techniques. Because molecular diagnostic methods are generally rather difficult to perform manually without highly trained users, automated and integrated systems are highly desirable but too costly for use at point-of-care or low-resource settings. Here, we showcase the development of a low-cost and rapid nucleic acid isolation and amplification platform by modifying entry-level 3D printers that cost between $400 and $750. Our modifications consisted of replacing the extruder with a tip-comb attachment that houses magnets to conduct magnetic particle-based nucleic acid extraction. We then programmed the 3D printer to conduct motions that can perform high-quality extraction protocols. Up to 12 samples can be processed simultaneously in under 13 minutes and the efficiency of nucleic acid isolation matches well against gold-standard spin-column-based extraction technology. Additionally, we used the 3D printer’s heated bed to supply heat to perform water bath-based polymerase chain reactions (PCRs). Using another attachment to hold PCR tubes, the 3D printer was programmed to automate the process of shuttling PCR tubes between water baths. By eliminating the temperature ramping needed in most commercial thermal cyclers, the run time of a 35-cycle PCR protocol was shortened by 33%. This article demonstrates that for applications in resource-limited settings, expensive nucleic acid extraction devices and thermal cyclers that are used in many central laboratories can be potentially replaced by a device modified from inexpensive entry-level 3D printers. PMID:27362424

  9. Low-Cost 3D Printers Enable High-Quality and Automated Sample Preparation and Molecular Detection.

    Directory of Open Access Journals (Sweden)

    Kamfai Chan

    Full Text Available Most molecular diagnostic assays require upfront sample preparation steps to isolate the target's nucleic acids, followed by its amplification and detection using various nucleic acid amplification techniques. Because molecular diagnostic methods are generally rather difficult to perform manually without highly trained users, automated and integrated systems are highly desirable but too costly for use at point-of-care or low-resource settings. Here, we showcase the development of a low-cost and rapid nucleic acid isolation and amplification platform by modifying entry-level 3D printers that cost between $400 and $750. Our modifications consisted of replacing the extruder with a tip-comb attachment that houses magnets to conduct magnetic particle-based nucleic acid extraction. We then programmed the 3D printer to conduct motions that can perform high-quality extraction protocols. Up to 12 samples can be processed simultaneously in under 13 minutes and the efficiency of nucleic acid isolation matches well against gold-standard spin-column-based extraction technology. Additionally, we used the 3D printer's heated bed to supply heat to perform water bath-based polymerase chain reactions (PCRs. Using another attachment to hold PCR tubes, the 3D printer was programmed to automate the process of shuttling PCR tubes between water baths. By eliminating the temperature ramping needed in most commercial thermal cyclers, the run time of a 35-cycle PCR protocol was shortened by 33%. This article demonstrates that for applications in resource-limited settings, expensive nucleic acid extraction devices and thermal cyclers that are used in many central laboratories can be potentially replaced by a device modified from inexpensive entry-level 3D printers.

  10. Application of quality by design to the development of analytical separation methods.

    Science.gov (United States)

    Orlandini, Serena; Pinzauti, Sergio; Furlanetto, Sandra

    2013-01-01

    Recent pharmaceutical regulatory documents have stressed the critical importance of applying quality by design (QbD) principles for in-depth process understanding to ensure that product quality is built in by design. This article outlines the application of QbD concepts to the development of analytical separation methods, for example chromatography and capillary electrophoresis. QbD tools, for example risk assessment and design of experiments, enable enhanced quality to be integrated into the analytical method, enabling earlier understanding and identification of variables affecting method performance. A QbD guide is described, from identification of quality target product profile to definition of control strategy, emphasizing the main differences from the traditional quality by testing (QbT) approach. The different ways several authors have treated single QbD steps of method development are reviewed and compared. In a final section on outlook, attention is focused on general issues which have arisen from the surveyed literature, and on the need to change the researcher's mindset from the QbT to QbD approach as an important analytical trend for the near future.

  11. 77 FR 50692 - Request for Information on Quality Measurement Enabled by Health IT-Extension Date for Responses

    Science.gov (United States)

    2012-08-22

    ... capture, manual chart abstraction, and the analysis of administrative claims data. Through this notice... quality measures which may be retooled versions of established paper-based or administrative data-driven...

  12. A Robust Design Method in Product Quality Applications

    Institute of Scientific and Technical Information of China (English)

    ZHANG Shi-an

    2003-01-01

    In order to express information on the quality grade of product designed, the target value of product quality design was described with a fuzzy number in this paper. An alternative to Taguchi′s, the robustness application design method has been recently presented. However, neither Taguchi′s method nor the alternative method is capable of dealing satisfactorily with the frequently encountered situations in which all the noise variables cannot be studied simultaneously. Based on the ideas from response surface modeling, linear models theory, and random effects models, we provide a method for estimation in the robustness application design method in product quality applications. With this new method used, the high-quality ratio of the product designed could be increased, and the ability to resist the influence of various disturbing factors and noise factors could be enhanced.

  13. Modern methods of wine quality analysis

    Directory of Open Access Journals (Sweden)

    Галина Зуфарівна Гайда

    2015-06-01

    Full Text Available  In this paper physical-chemical and enzymatic methods of quantitative analysis of the basic wine components were reviewed. The results of own experiments were presented for the development of enzyme- and cell-based amperometric sensors on ethanol, lactate, glucose, arginine

  14. A highly parallel method for synthesizing DNA repeats enables the discovery of ‘smart’ protein polymers

    Science.gov (United States)

    Amiram, Miriam; Quiroz, Felipe Garcia; Callahan, Daniel J.; Chilkoti, Ashutosh

    2011-02-01

    Robust high-throughput synthesis methods are needed to expand the repertoire of repetitive protein-polymers for different applications. To address this need, we developed a new method, overlap extension rolling circle amplification (OERCA), for the highly parallel synthesis of genes encoding repetitive protein-polymers. OERCA involves a single PCR-type reaction for the rolling circle amplification of a circular DNA template and simultaneous overlap extension by thermal cycling. We characterized the variables that control OERCA and demonstrated its superiority over existing methods, its robustness, high-throughput and versatility by synthesizing variants of elastin-like polypeptides (ELPs) and protease-responsive polymers of glucagon-like peptide-1 analogues. Despite the GC-rich, highly repetitive sequences of ELPs, we synthesized remarkably large genes without recursive ligation. OERCA also enabled us to discover ‘smart’ biopolymers that exhibit fully reversible thermally responsive behaviour. This powerful strategy generates libraries of repetitive genes over a wide and tunable range of molecular weights in a ‘one-pot’ parallel format.

  15. The Concept of a Method Ensuring Aeronautical Data Quality

    Directory of Open Access Journals (Sweden)

    Dudek Ewa

    2016-07-01

    Full Text Available The paper presents the concept of a method ensuring quality of aeronautical data. European Union (among others UE 73/2010 as well as international (among others ICAO Annex 15 regulations introduce a number of requirements regarding the quality and safety of aeronautical data. Those directives set up a complementary regulations system. However with their objective and scope they determine mainly the specifications and requirements that are to be implemented and compatible. Mentioned regulations also refer to selected international standards (e.g. ISO 19157, focused on quality and safety of geographic data and information. Nevertheless within the scope of considered regulations and norms no algorithms and methods of ensuring required quality in the process of aeronautical data collection and processing were determined. Taking into account the identified needs, authors proposed the application of statistical method for process quality management – six-sigma.

  16. Internal quality audit and quality standards as a method of quality improvement at the Department of Ophthalmology, University Hospital.

    Science.gov (United States)

    Nasić, Mirjana; Pokupec, Rajko; Katusić, Damir; Miklić, Pavle; Suić, Ivan; Galić, Slobodan

    2005-01-01

    Quality assessment of clinical health care with the programme of quality standard is a method of health management, through which better efficiency and safety of health outcomes can be achieved. In the period from 2002 to 2004, a pilot program of quality has been carried out on the Department of Ophthalmology, University Hospital Center in Zagreb. Seven internal audit teams of hospital commission and teams of hospital departments were evaluating introducing practice for quality standards every three months. In the period of two years improvement in all standards of quality has been noticed (expressed in percent of progress towards the ideal result of 100%): personnel 20%, patient rights 15%, medical equipment 40%, quality of emergency service 60%, implementation of clinical guidelines and criteria for elective admission 55%, quality of risk prevention 70%, quality of medical records 60%. The two-years-improvement dynamics of about 46%, first year 24%.

  17. Rapid methods : for food and feed quality determination

    NARCIS (Netherlands)

    Amerongen, van A.; Barug, D.; Lauwaars, M.

    2007-01-01

    There is an ever-increasing need for rapid methods and instrumentation in the field of food and feed quality. Key issues dealt with in the food and feed industry include: monitoring of processes at all stages; showing due diligence in the control of food and nutritional quality; achieving rapid

  18. Rapid methods : for food and feed quality determination

    NARCIS (Netherlands)

    Amerongen, van A.; Barug, D.; Lauwaars, M.

    2007-01-01

    There is an ever-increasing need for rapid methods and instrumentation in the field of food and feed quality. Key issues dealt with in the food and feed industry include: monitoring of processes at all stages; showing due diligence in the control of food and nutritional quality; achieving rapid resu

  19. Developing and executing quality improvement projects (concept, methods, and evaluation).

    Science.gov (United States)

    Likosky, Donald S

    2014-03-01

    Continuous quality improvement, quality assurance, cycles of change--these words of often used to express the process of using data to inform and improve clinical care. Although many of us have been exposed to theories and practice of experimental work (e.g., randomized trial), few of us have been similarly exposed to the science underlying quality improvement. Through the lens of a single-center quality improvement study, this article exposes the reader to methodology for conducting such studies. The reader will gain an understanding of these methods required to embark on such a study.

  20. A bootstrap method for estimating uncertainty of water quality trends

    Science.gov (United States)

    Hirsch, Robert M.; Archfield, Stacey A.; DeCicco, Laura

    2015-01-01

    Estimation of the direction and magnitude of trends in surface water quality remains a problem of great scientific and practical interest. The Weighted Regressions on Time, Discharge, and Season (WRTDS) method was recently introduced as an exploratory data analysis tool to provide flexible and robust estimates of water quality trends. This paper enhances the WRTDS method through the introduction of the WRTDS Bootstrap Test (WBT), an extension of WRTDS that quantifies the uncertainty in WRTDS-estimates of water quality trends and offers various ways to visualize and communicate these uncertainties. Monte Carlo experiments are applied to estimate the Type I error probabilities for this method. WBT is compared to other water-quality trend-testing methods appropriate for data sets of one to three decades in length with sampling frequencies of 6–24 observations per year. The software to conduct the test is in the EGRETci R-package.

  1. Methods of multicriterion estimations in system total quality management

    Directory of Open Access Journals (Sweden)

    Nikolay V. Diligenskiy

    2011-05-01

    Full Text Available In this article the method of multicriterion comparative estimation of efficiency (Data Envelopment Analysis and possibility of its application in system of total quality management is considered.

  2. Ripening stage and drying method affecting colour and quality ...

    African Journals Online (AJOL)

    STORAGESEVER

    Key words: Ber, drying method, post harvest quality, blanching, fruit colour, harvesting stage. ... ground following abscission, throwing stones and sticks into the trees, hitting ... of insect larva inside each individual fruits. .... Climate change and.

  3. Methods Reduce Cost, Enhance Quality of Nanotubes

    Science.gov (United States)

    2009-01-01

    efforts with carbon nanotubes have made it a global leader in this field. Among the many examples are Johnson Space Center s Carbon Nanotube Project, which focuses on bulk nanotube production, purification, and application, and Goddard Space Flight Center s improved arc discharge method of nanotube production, developed under the direction of Jeannette Benavides (featured in Spinoff 2007 and 2008). While the Agency continues its own research, it partners with private companies to advance this unique technology for use on Earth as well as among the stars.

  4. A Robust Tolerance Design Method Based on Fuzzy Quality Loss

    Institute of Scientific and Technical Information of China (English)

    CAO Yan-long; MAO Jian; YANG Jiang-xin; WU Zhao-tong; WU Li-qun

    2006-01-01

    The traditional tolerance design model ignores the impact of noise factor,so that the design may be infeasible due to variations in design constraints.Based on the analysis of fuzzy factors in tolerance design and the limitations ofthe traditional Taguchi squared quality loss function,a fuzzy quality loss function model utilizing fuzzy theory was introduced.Concepts on fuzzy quality loss and fuzzy quality loss cost were proposed in the model.The characteristics of the new model and the advantages over the traditional Taguchi quality loss function were analyzed.A robust tolerance design model using a fuzzy quality loss function was proposed.An example was given to illustrate the proposed model.Results and comparisons show that the method is suitable and reliable,and makes the conclusions more objective and reasonable.

  5. Use of quality planning methods in optimizing welding wire quality characteristics

    Directory of Open Access Journals (Sweden)

    D. Vykydal

    2013-10-01

    Full Text Available The quality of a product is given by the extent, to which the product meets customer requirements. It is generally accepted that the extent, to which the product meets such customer requirements, and, consequently, the resulting quality of the product itself, substantially depend on the early stages of the product lifecycle, i.e. on the design and development stages. Appropriate means for effective product quality planning can be found among quality management methods and tools. These methods are typically employed in engineering production and automotive industry. This paper focuses on exploring the potential of Quality Function Deployment (QFD and Failure Mode and Effect Analysis (FMEA methods for use in metallurgical production, an industrial branch where they have not been commonly employed as yet.

  6. New approach to equipment quality evaluation method with distinct functions

    Directory of Open Access Journals (Sweden)

    Milisavljević Vladimir M.

    2016-01-01

    Full Text Available The paper presents new approach for improving method for quality evaluation and selection of equipment (devices and machinery by applying distinct functions. Quality evaluation and selection of devices and machinery is a multi-criteria problem which involves the consideration of numerous parameters of various origins. Original selection method with distinct functions is based on technical parameters with arbitrary evaluation of each parameter importance (weighting. Improvement of this method, presented in this paper, addresses the issue of weighting of parameters by using Delphi Method. Finally, two case studies are provided, which included quality evaluation of standard boilers for heating and evaluation of load-haul-dump (LHD machines, to demonstrate applicability of this approach. Analytical Hierarchical Process (AHP is used as a control method.

  7. A new method for calculation of an air quality index

    Energy Technology Data Exchange (ETDEWEB)

    Ilvessalo, P. [Finnish Meteorological Inst., Helsinki (Finland). Air Quality Dept.

    1995-12-31

    Air quality measurement programs in Finnish towns have expanded during the last few years. As a result of this it is more and more difficult to make use of all the measured concentration data. Citizens of Finnish towns are nowadays taking more of an interest in the air quality of their surroundings. The need to describe air quality in a simplified form has increased. Air quality indices permit the presentation of air quality data in such a way that prevailing conditions are more easily understandable than when using concentration data as such. Using an air quality index always means that some of the information about concentrations of contaminants in the air will be lost. How much information is possible to extract from a single index number depends on the calculation method. A new method for the calculation of an air quality index has been developed. This index always indicates the overstepping of an air quality guideline level. The calculation of this air quality index is performed using the concentrations of all the contaminants measured. The index gives information both about the prevailing air quality and also the short-term trend. It can also warn about the expected exceeding of guidelines due to one or several contaminants. The new index is especially suitable for the real-time monitoring and notification of air quality values. The behaviour of the index was studied using material from a measurement period in the spring of 1994 in Kaepylae, Helsinki. Material from a pre-operational period in the town of Oulu was also available. (author)

  8. A molecular switch in the scaffold NHERF1 enables misfolded CFTR to evade the peripheral quality control checkpoint.

    Science.gov (United States)

    Loureiro, Cláudia A; Matos, Ana Margarida; Dias-Alves, Ângela; Pereira, Joana F; Uliyakina, Inna; Barros, Patrícia; Amaral, Margarida D; Matos, Paulo

    2015-05-19

    The peripheral protein quality control (PPQC) checkpoint removes improperly folded proteins from the plasma membrane through a mechanism involving the E3 ubiquitin ligase CHIP (carboxyl terminus of Hsc70 interacting protein). PPQC limits the efficacy of some cystic fibrosis (CF) drugs, such as VX-809, that improve trafficking to the plasma membrane of misfolded mutants of the CF transmembrane conductance regulator (CFTR), including F508del-CFTR, which retains partial functionality. We investigated the PPQC checkpoint in lung epithelial cells with F508del-CFTR that were exposed to VX-809. The conformation of the scaffold protein NHERF1 (Na(+)/H(+) exchange regulatory factor 1) determined whether the PPQC recognized "rescued" F508del-CFTR (the portion that reached the cell surface in VX-809-treated cells). Activation of the cytoskeletal regulator Rac1 promoted an interaction between the actin-binding adaptor protein ezrin and NHERF1, triggering exposure of the second PDZ domain of NHERF1, which interacted with rescued F508del-CFTR. Because binding of F508del-CFTR to the second PDZ of NHERF1 precluded the recruitment of CHIP, the coexposure of airway cells to Rac1 activator nearly tripled the efficacy of VX-809. Interference with the NHERF1-ezrin interaction prevented the increase of efficacy of VX-809 by Rac1 activation, but the actin-binding domain of ezrin was not required for the increase in efficacy. Thus, rather than mainly directing anchoring of F508del-CFTR to the actin cytoskeleton, induction of ezrin activation by Rac1 signaling triggered a conformational change in NHERF1, which was then able to bind and stabilize misfolded CFTR at the plasma membrane. These insights into the cell surface stabilization of CFTR provide new targets to improve treatment of CF.

  9. CONTACTLESS METHODS FOR QUALITY EVALUATION OF DAIRY PRODUCTS

    Directory of Open Access Journals (Sweden)

    Zlatin Zlatev

    2016-07-01

    Full Text Available The aim of the report is to present a comparative analysis of the methods and technical means for assessment of the quality and safety of dairy products, particularly yellow cheese by spectral characteristics. As a result of the analysis are established appropriate methods for representation of the spectral characteristics and classification of the researched product. In the development are shown and evaluated the accuracy and performance of the results of studies conducted in the laboratory of the Trakia University, faculty of Technics and technologies with the discussed methods for evaluation the quality of the food product.

  10. A new embedding quality assessment method for manifold learning

    CERN Document Server

    Zhang, Peng; Zhang, Bo

    2011-01-01

    Manifold learning is a hot research topic in the field of computer science. A crucial issue with current manifold learning methods is that they lack a natural quantitative measure to assess the quality of learned embeddings, which greatly limits their applications to real-world problems. In this paper, a new embedding quality assessment method for manifold learning, named as Normalization Independent Embedding Quality Assessment (NIEQA), is proposed. Compared with current assessment methods which are limited to isometric embeddings, the NIEQA method has a much larger application range due to two features. First, it is based on a new measure which can effectively evaluate how well local neighborhood geometry is preserved under normalization, hence it can be applied to both isometric and normalized embeddings. Second, it can provide both local and global evaluations to output an overall assessment. Therefore, NIEQA can serve as a natural tool in model selection and evaluation tasks for manifold learning. Experi...

  11. Sustainable green urban planning: the workbench spatial quality method

    NARCIS (Netherlands)

    Cilliers, E.J.; Diemont, E.; Stobbelaar, Derk Jan; Timmermans, W.

    2011-01-01

    Purpose – Amersfoort Local Municipality implemented the workbench spatial quality method (referred to as workbench method) to enhance participation in green-planning processes. Design/methodology/approach – As part of the Valuing Attractive Landscapes in the Urban Economy project (made possible by I

  12. Methods of the Quality of Higher Education Social Assessment

    Science.gov (United States)

    Artushina, Irina; Troyan, Vladimir

    2007-01-01

    This article describes the methodical problems of the ranking of Russian universities by the independent ranking agency RatER. The main features of this ranking system are public estimations of the quality of the higher education in Russia. The results of the sociological study were processed by the original statistical methods. The procedure…

  13. Sustainable green urban planning: the workbench spatial quality method

    NARCIS (Netherlands)

    Cilliers, E.J.; Diemont, E.; Stobbelaar, Derk Jan; Timmermans, W.

    2011-01-01

    Purpose – Amersfoort Local Municipality implemented the workbench spatial quality method (referred to as workbench method) to enhance participation in green-planning processes. Design/methodology/approach – As part of the Valuing Attractive Landscapes in the Urban Economy project (made possible by

  14. Determining a Method of Enabling and Disabling the Integral Torque in the SDO Science and Inertial Mode Controllers

    Science.gov (United States)

    Vess, Melissa F.; Starin, Scott R.

    2007-01-01

    During design of the SDO Science and Inertial mode PID controllers, the decision was made to disable the integral torque whenever system stability was in question. Three different schemes were developed to determine when to disable or enable the integral torque, and a trade study was performed to determine which scheme to implement. The trade study compared complexity of the control logic, risk of not reenabling the integral gain in time to reject steady-state error, and the amount of integral torque space used. The first scheme calculated a simplified Routh criterion to determine when to disable the integral torque. The second scheme calculates the PD part of the torque and looked to see if that torque would cause actuator saturation. If so, only the PD torque is used. If not, the integral torque is added. Finally, the third scheme compares the attitude and rate errors to limits and disables the integral torque if either of the errors is greater than the limit. Based on the trade study results, the third scheme was selected. Once it was decided when to disable the integral torque, analysis was performed to determine how to disable the integral torque and whether or not to reset the integrator once the integral torque was reenabled. Three ways to disable the integral torque were investigated: zero the input into the integrator, which causes the integral part of the PID control torque to be held constant; zero the integral torque directly but allow the integrator to continue integrating; or zero the integral torque directly and reset the integrator on integral torque reactivation. The analysis looked at complexity of the control logic, slew time plus settling time between each calibration maneuver step, and ability to reject steady-state error. Based on the results of the analysis, the decision was made to zero the input into the integrator without resetting it. Throughout the analysis, a high fidelity simulation was used to test the various implementation methods.

  15. Video quality experts group: the quest for valid objective methods

    Science.gov (United States)

    Corriveau, Philip J.; Webster, Arthur A.; Rohaly, Ann M.; Libert, John M.

    2000-06-01

    Subjective assessment methods have been used reliably for many years to evaluate video quality. They continue to provide the most reliable assessments compared to objective methods. Some issues that arise with subjective assessment include the cost of conducting the evaluations and the fact that these methods cannot easily be used to monitor video quality in real time. Furthermore, traditional, analog objective methods, while still necessary, are not sufficient to measure the quality of digitally compressed video systems. Thus, there is a need to develop new objective methods utilizing the characteristics of the human visual system. While several new objective methods have been developed, there is to date no internationally standardized method. The Video Quality Experts Group (VQEG) was formed in October 1997 to address video quality issues. The group is composed of experts from various backgrounds and affiliations, including participants from several internationally recognized organizations working in the field of video quality assessment. The majority of participants are active in the International Telecommunications Union (ITU) and VQEG combines the expertise and resources found in several ITU Study Groups to work towards a common goal. The first task undertaken by VQEG was to provide a validation of objective video quality measurement methods leading to Recommendations in both the Telecommunications (ITU-T) and Radiocommunication (ITU-R) sectors of the ITU. To this end, VQEG designed and executed a test program to compare subjective video quality evaluations to the predictions of a number of proposed objective measurement methods for video quality in the bit rate range of 768 kb/s to 50 Mb/s. The results of this test show that there is no objective measurement system that is currently able to replace subjective testing. Depending on the metric used for evaluation, the performance of eight or nine models was found to be statistically equivalent, leading to the

  16. A Quality Based Method to Analyze Software Architectures

    Directory of Open Access Journals (Sweden)

    Farzaneh Hoseini Jabali

    2011-07-01

    Full Text Available In order to produce and develop a software system, it is necessary to have a method of choosing a suitable software architecture which satisfies the required quality attributes and maintains a trade-off between sometimes conflicting ones. Each software architecture includes a set of design decisions for each of which there are various alternatives, satisfying the quality attributes differently. At the same time various stakeholders with various quality goals participate in decision-making. In this paper a numerical method is proposed that based on the quality attributes selects the suitable software architecture for a certain software. In this method, for each design decision, different alternatives are compared in view of a certain quality attribute, and the other way around. Multi-criteria decision-making methods are used and, at the same time, time and cost constraints are considered in decision-making, too. The proposed method applies the stakeholders' opinions in decision-making according to the degree of their importance and helps the architect to select the best software architecture with more certainty.

  17. A new assessment method for image fusion quality

    Science.gov (United States)

    Li, Liu; Jiang, Wanying; Li, Jing; Yuchi, Ming; Ding, Mingyue; Zhang, Xuming

    2013-03-01

    Image fusion quality assessment plays a critically important role in the field of medical imaging. To evaluate image fusion quality effectively, a lot of assessment methods have been proposed. Examples include mutual information (MI), root mean square error (RMSE), and universal image quality index (UIQI). These image fusion assessment methods could not reflect the human visual inspection effectively. To address this problem, we have proposed a novel image fusion assessment method which combines the nonsubsampled contourlet transform (NSCT) with the regional mutual information in this paper. In this proposed method, the source medical images are firstly decomposed into different levels by the NSCT. Then the maximum NSCT coefficients of the decomposed directional images at each level are obtained to compute the regional mutual information (RMI). Finally, multi-channel RMI is computed by the weighted sum of the obtained RMI values at the various levels of NSCT. The advantage of the proposed method lies in the fact that the NSCT can represent image information using multidirections and multi-scales and therefore it conforms to the multi-channel characteristic of human visual system, leading to its outstanding image assessment performance. The experimental results using CT and MRI images demonstrate that the proposed assessment method outperforms such assessment methods as MI and UIQI based measure in evaluating image fusion quality and it can provide consistent results with human visual assessment.

  18. Sports Injury Surveillance Systems: A Review of Methods and Data Quality.

    Science.gov (United States)

    Ekegren, Christina L; Gabbe, Belinda J; Finch, Caroline F

    2016-01-01

    Data from sports injury surveillance systems are a prerequisite to the development and evaluation of injury prevention strategies. This review aimed to identify ongoing sports injury surveillance systems and determine whether there are gaps in our understanding of injuries in certain sport settings. A secondary aim was to determine which of the included surveillance systems have evaluated the quality of their data, a key factor in determining their usefulness. A systematic search was carried out to identify (1) publications presenting methodological details of sports injury surveillance systems within clubs and organisations; and (2) publications describing quality evaluations and the quality of data from these systems. Data extracted included methodological details of the surveillance systems, methods used to evaluate data quality, and results of these evaluations. Following literature search and review, a total of 15 sports injury surveillance systems were identified. Data relevant to each aim were summarised descriptively. Most systems were found to exist within professional and elite sports. Publications concerning data quality were identified for seven (47%) systems. Validation of system data through comparison with alternate sources has been undertaken for only four systems (27%). This review identified a shortage of ongoing injury surveillance data from amateur and community sport settings and limited information about the quality of data in professional and elite settings. More surveillance systems are needed across a range of sport settings, as are standards for data quality reporting. These efforts will enable better monitoring of sports injury trends and the development of sports safety strategies.

  19. How to assess the quality of your analytical method?

    Science.gov (United States)

    Topic, Elizabeta; Nikolac, Nora; Panteghini, Mauro; Theodorsson, Elvar; Salvagno, Gian Luca; Miler, Marijana; Simundic, Ana-Maria; Infusino, Ilenia; Nordin, Gunnar; Westgard, Sten

    2015-10-01

    Laboratory medicine is amongst the fastest growing fields in medicine, crucial in diagnosis, support of prevention and in the monitoring of disease for individual patients and for the evaluation of treatment for populations of patients. Therefore, high quality and safety in laboratory testing has a prominent role in high-quality healthcare. Applied knowledge and competencies of professionals in laboratory medicine increases the clinical value of laboratory results by decreasing laboratory errors, increasing appropriate utilization of tests, and increasing cost effectiveness. This collective paper provides insights into how to validate the laboratory assays and assess the quality of methods. It is a synopsis of the lectures at the 15th European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) Continuing Postgraduate Course in Clinical Chemistry and Laboratory Medicine entitled "How to assess the quality of your method?" (Zagreb, Croatia, 24-25 October 2015). The leading topics to be discussed include who, what and when to do in validation/verification of methods, verification of imprecision and bias, verification of reference intervals, verification of qualitative test procedures, verification of blood collection systems, comparability of results among methods and analytical systems, limit of detection, limit of quantification and limit of decision, how to assess the measurement uncertainty, the optimal use of Internal Quality Control and External Quality Assessment data, Six Sigma metrics, performance specifications, as well as biological variation. This article, which continues the annual tradition of collective papers from the EFLM continuing postgraduate courses in clinical chemistry and laboratory medicine, aims to provide further contributions by discussing the quality of laboratory methods and measurements and, at the same time, to offer continuing professional development to the attendees.

  20. Enabling the Usability of Earth Science Data Products and Services by Evaluating, Describing, and Improving Data Quality throughout the Data Lifecycle

    Science.gov (United States)

    Downs, R. R.; Peng, G.; Wei, Y.; Ramapriyan, H.; Moroni, D. F.

    2015-12-01

    Earth science data products and services are being used by representatives of various science and social science disciplines, by planning and decision-making professionals, by educators and learners ranging from primary through graduate and informal education, and by the general public. The diversity of users and uses of Earth science data is gratifying and offers new challenges for enabling the usability of these data by audiences with various purposes and levels of expertise. Users and other stakeholders need capabilities to efficiently find, explore, select, and determine the applicability and suitability of data products and services to meet their objectives and information needs. Similarly, they need to be able to understand the limitations of Earth science data, which can be complex, especially when considering combined or simultaneous use of multiple data products and services. Quality control efforts of stakeholders, throughout the data lifecycle, can contribute to the usability of Earth science data to meet the needs of diverse users. Such stakeholders include study design teams, data producers, data managers and curators, archives, systems professionals, data distributors, end-users, intermediaries, sponsoring organizations, hosting institutions, and others. Opportunities for engaging stakeholders to review, describe, and improve the quality of Earth science data products and services throughout the data lifecycle are identified and discussed. Insight is shared from the development of guidelines for implementing the Group on Earth Observations (GEO) Data Management Principles, the recommendations from the Earth Science Data System Working Group (ESDSWG) on Data Quality, and the efforts of the Information Quality Cluster of the Federation of Earth Science Information Partners (ESIP). Examples and outcomes from quality control efforts of data facilities, such as scientific data centers, that contribute to the usability of Earth science data also are offered.

  1. The Role of Laser Additive Manufacturing Methods of Metals in Repair, Refurbishment and Remanufacturing - Enabling Circular Economy

    Science.gov (United States)

    Leino, Maija; Pekkarinen, Joonas; Soukka, Risto

    Circular economy is an economy model where products, components, and materials are aimed to be kept at their highest utility and value at all times. Repair, refurbishment and remanufacturing processes are procedures aiming at returning the value of the product during its life cycle. Additive manufacturing (AM) is expected to be an enabling technology in circular economy based business models. One of AM process that enables repair, refurbishment and remanufacturing is Directed Energy Deposition. Respectively Powder Bed Fusion enables manufacturing of replacement components on demand. The aim of this study is to identify the current research findings and state of art of utilizing AM in repair, refurbishment and remanufacturing processes of metallic products. The focus is in identifying possibilities of AM in promotion of circular economy and expected environmental benefits based on the found literature. Results of the study indicate significant potential in utilizing AM in repair, refurbishment and remanufacturing activities.

  2. Power quality events recognition using a SVM-based method

    Energy Technology Data Exchange (ETDEWEB)

    Cerqueira, Augusto Santiago; Ferreira, Danton Diego; Ribeiro, Moises Vidal; Duque, Carlos Augusto [Department of Electrical Circuits, Federal University of Juiz de Fora, Campus Universitario, 36036 900, Juiz de Fora MG (Brazil)

    2008-09-15

    In this paper, a novel SVM-based method for power quality event classification is proposed. A simple approach for feature extraction is introduced, based on the subtraction of the fundamental component from the acquired voltage signal. The resulting signal is presented to a support vector machine for event classification. Results from simulation are presented and compared with two other methods, the OTFR and the LCEC. The proposed method shown an improved performance followed by a reasonable computational cost. (author)

  3. Image quality improvement for underground radar by block migration method

    Science.gov (United States)

    Ho, Gwangsu; Kawanaka, Akira; Takagi, Mikio

    1993-11-01

    Techniques have been developed which have been imaging optically opaque regions using an electromagnetic wave radar in order to estimate the location of the objects in those regions. One important application of these techniques is the detection of buried pipes and cables. In the case of underground radar, its image quality often becomes low because the nature of the soil is not uniform and an electromagnetic wave is attenuated in soil. Hence, the method which improves the quality of the radar images is required. In this paper, we point out that the quality of underground images can be improved significantly by means of the block migration method. In this method LOT (Lapped Orthogonal Transform) was applied. LOT is a new block transform method in which basis functions overlap in adjacent blocks, and it has a fast computation algorithm. In addition to above, we propose a method of estimating dielectric constant in soil using the processed images. The result of applying the block migration method to the underground radar images are presented. It points out the good capability for the image quality improvement and the application of LOT can improve the influence by blocking and the processing time. Also the dielectric constant in each block can be estimated accurately.

  4. A systematic review of quality assessment methods for smartphone health apps.

    Science.gov (United States)

    BinDhim, Nasser F; Hawkey, Alexandra; Trevena, Lyndal

    2015-02-01

    There are large numbers of health-related applications (apps) available in various app stores for many smartphone devices. Consequently, increasing numbers of articles are attempting to evaluate the content and the quality of health-related smartphone apps for specific health conditions. The aim of this article is to describe and summarize the methodologies used to determine the quality of health-related apps targeting health consumers and to propose a set of criteria for evaluating the quality of smartphone health-related apps. In 2013, literature searches were performed using Medline and CINAHL, and we included all articles that had the aim of assessing the quality of health-related smartphone apps. The assessment method used in these studies was summarized and scored using a set of quality criteria developed for this study. From 606 articles generated by the search, only 10 met the inclusion criteria. Based on our quality criteria, the mean score was 5.05 out of 8 (range, 2-7). Eighty percent of the studies did not identify the app store country in which the apps were found. Forty percent of the studies did not clearly mention whether they only had assessed the app description or had downloaded the app content for evaluation. Sixty percent of the studies did not provide a list of the apps they had evaluated. Overall, we identified six evaluation methodologies used to assess the quality of health-related apps described in RESULTS. This article provides a summary of currently used methods for assessing the quality of smartphone health-related apps and proposes a set of criteria to enable future studies to consistently review health-related app quality in a standardized manner.

  5. Scatterscore method to evaluate changes in water quality

    Energy Technology Data Exchange (ETDEWEB)

    Kim, A.G.; Cardone, C. [U.S. Department of Energy, Pittsburgh, PA (United States). National Energy Technology Laboratory

    2001-07-01

    In Pennsylvania, water quality is monitored at mine sites remediated with coal combustion by-products (CCB), on a quarterly or annual basis. This produces extensive data files including values for 32 parameters that are difficult to evaluate for overall changes in water quality. Tracking a few major parameters, such as pH, Fe or acidity, produces a complex data set that excludes other significant values. A quantitative measure of estimating if the overall change in water quality is an improvement, no significant change or deterioration should take into account all measured quantities. To assess the change in water quality at a site, a scatterscore evaluation was developed. In this reconnaissance method, a score is calculated based on the differences between up gradient (control) versus down gradient (treatment) water quality data sets. All parameters measured over a period of time at two sampling points are compared. This evaluation method indicated that there was slight to moderate improvement in water quality at 30% of the CCB remediated sites and slight deterioration at 25% of the sites. The scatterscore at the remaining sites indicated random change in the measured parameters. 19 refs., 7 figs., 5 tabs.

  6. Reduced-reference image quality assessment using moment method

    Science.gov (United States)

    Yang, Diwei; Shen, Yuantong; Shen, Yongluo; Li, Hongwei

    2016-10-01

    Reduced-reference image quality assessment (RR IQA) aims to evaluate the perceptual quality of a distorted image through partial information of the corresponding reference image. In this paper, a novel RR IQA metric is proposed by using the moment method. We claim that the first and second moments of wavelet coefficients of natural images can have approximate and regular change that are disturbed by different types of distortions, and that this disturbance can be relevant to human perceptions of quality. We measure the difference of these statistical parameters between reference and distorted image to predict the visual quality degradation. The introduced IQA metric is suitable for implementation and has relatively low computational complexity. The experimental results on Laboratory for Image and Video Engineering (LIVE) and Tampere Image Database (TID) image databases indicate that the proposed metric has a good predictive performance.

  7. A Method for Assessing Quality of Service in Broadband Networks

    DEFF Research Database (Denmark)

    Bujlow, Tomasz; Riaz, M. Tahir; Pedersen, Jens Myrup

    2012-01-01

    Monitoring of Quality of Service (QoS) in high-speed Internet infrastructure is a challenging task. However, precise assessments must take into account the fact that the requirements for the given quality level are service-dependent. Backbone QoS monitoring and analysis requires processing of large...... taken from the description of system sockets. This paper proposes a new method for measuring the Quality of Service (QoS) level in broadband networks, based on our Volunteer-Based System for collecting the training data, Machine Learning Algorithms for generating the classification rules and application...... and provide C5.0 high-quality training data, divided into groups corresponding to different types of applications. It was found that currently existing means of collecting data (classification by ports, Deep Packet Inspection, statistical classification, public data sources) are not sufficient and they do...

  8. QUANTIFYING SUPPLIERS’ PRODUCT QUALITY: AN EXPLORATORY PRODUCT AUDIT METHOD

    Directory of Open Access Journals (Sweden)

    S. Avakh Darestani

    2012-01-01

    Full Text Available

    ENGLISH ABSTRACT:The quality of the raw material and supplied product from suppliers plays a critical role in the quality of the final product. It has become the norm that vehicle manufacturers require their suppliers to measure product quality and service with a product audit method. Measuring quality of product is emphasised by QS9000 VDA6.5 and ISO/TS16949. From a competitive standpoint, and also to see continuous improvement in business, companies need to monitor their suppliers’ performance. Quality and delivery are two very important indicators of supplier performance. This paper presents a statistical method for measuring the quality of supplied product. This method allocates different weights to variables and attributes characteristics. Moreover, following normal distribution, the tolerance zone is divided to three regions with different scores. Therefore, the quality of suppliers’ products can be monitored based on the Product Quality Audit Score (PQAS. However, this method may be employed for organisations to monitor their raw material, work-in-process parts, and final product. It can be an indicator to monitor supplier quality behaviour.

    AFRIKAANSE OPSOMMING: Die gehalte van grondstowwe en produkte/komponente wat deur leweransiers verskaf word, speel ‘n kritiese rol in die gehalte van die finale produk. Dit het die norm geword in die motorvervaardigingsbedryf dat daar van leweransiers verwag word om hulle produkkwaliteit en –diens te meet by wyse van ‘n produkouditmetode. Die meting van produkkwaliteit word benadruk deur QS9000 VDA6.5 en ISO/TS16949. Uit ‘n mededingingshoek en ook om kontinue verbetering te monitor, is dit noodsaaklik dat leweransiers se verrigting gemeet word. Gehalte en aflewering is twee van die belangrikste indikatore van leweransiersverrigting. In hierdie artikel word ‘n statistiese model voorgehou vir die meting van die kwaliteit van die gelewerde produk. Die metode ken verskillende

  9. Laboratory diagnostic methods, system of quality and validation

    Directory of Open Access Journals (Sweden)

    Ašanin Ružica

    2005-01-01

    Full Text Available It is known that laboratory investigations secure safe and reliable results that provide a final confirmation of the quality of work. Ideas, planning, knowledge, skills, experience, and environment, along with good laboratory practice, quality control and reliability of quality, make the area of biological investigations very complex. In recent years, quality control, including the control of work in the laboratory, is based on international standards and is used at that level. The implementation of widely recognized international standards, such as the International Standard ISO/IEC 17025 (1 and the implementing of the quality system series ISO/IEC 9000 (2 have become the imperative on the grounds of which laboratories have a formal, visible and corresponding system of quality. The diagnostic methods that are used must constantly yield results which identify the animal as positive or negative, and the precise status of the animal is determined with a predefined degree of statistical significance. Methods applied on a selected population reduce the risk of obtaining falsely positive or falsely negative results. A condition for this are well conceived and documented methods, with the application of the corresponding reagents, and work with professional and skilled staff. This process requires also a consistent implementation of the most rigorous experimental plans, epidemiological and statistical data and estimations, with constant monitoring of the validity of the applied methods. Such an approach is necessary in order to cut down the number of misconceptions and accidental mistakes, for a referent population of animals on which the validity of a method is tested. Once a valid method is included in daily routine investigations, it is necessary to apply constant monitoring for the purpose of internal quality control, in order adequately to evaluate its reproducibility and reliability. Consequently, it is necessary at least twice yearly to conduct

  10. Kansas's forests, 2005: statistics, methods, and quality assurance

    Science.gov (United States)

    Patrick D. Miles; W. Keith Moser; Charles J. Barnett

    2011-01-01

    The first full annual inventory of Kansas's forests was completed in 2005 after 8,868 plots were selected and 468 forested plots were visited and measured. This report includes detailed information on forest inventory methods and data quality estimates. Important resource statistics are included in the tables. A detailed analysis of Kansas inventory is presented...

  11. Methods of Quality Appraisal for Studies Reviewed by Evidence Clearinghouses

    Science.gov (United States)

    Wilson, Sandra Jo; Tanner-Smith, Emily

    2015-01-01

    This presentation will discuss quality appraisal methods for assessing research studies used in systematic reviews, research syntheses, and evidence-based practice repositories such as the What Works Clearinghouse. The different ways that the methodological rigor and risk of bias of primary studies included in syntheses is assessed means that…

  12. A new method to evaluate imaging quality of CCD cameras

    Institute of Scientific and Technical Information of China (English)

    LI Wen-juan; DU Hai-hui; DAI Jing-min; CHEN Ying-hang

    2005-01-01

    In order to evaluate the imaging quality of CCD cameras fully and rapidly,the minimum resolvable contrast (MRC) is presented in this paper and the system of measuring MRC is constructed as well,in which two integrating spheres are proposed to illuminate two sides of the target respectively.The variable contrast can be obtained by regulating the luminance of integrating spheres. Experimental results indicate that the error of measuring luminance is within ±0.3 cd/m2,MRC rises with the increase of the spatial frequency.The experimental results show that the method proposed is an effective approach to evaluate the imaging quality of CCD cameras.

  13. A Simple Method for Guaranteeing ECG Quality in Real-Time Wavelet Lossy Coding

    Directory of Open Access Journals (Sweden)

    Alesanco Álvaro

    2007-01-01

    Full Text Available Guaranteeing ECG signal quality in wavelet lossy compression methods is essential for clinical acceptability of reconstructed signals. In this paper, we present a simple and efficient method for guaranteeing reconstruction quality measured using the new distortion index wavelet weighted PRD (WWPRD, which reflects in a more accurate way the real clinical distortion of the compressed signal. The method is based on the wavelet transform and its subsequent coding using the set partitioning in hierarchical trees (SPIHT algorithm. By thresholding the WWPRD in the wavelet transform domain, a very precise reconstruction error can be achieved thus enabling to obtain clinically useful reconstructed signals. Because of its computational efficiency, the method is suitable to work in a real-time operation, thus being very useful for real-time telecardiology systems. The method is extensively tested using two different ECG databases. Results led to an excellent conclusion: the method controls the quality in a very accurate way not only in mean value but also with a low-standard deviation. The effects of ECG baseline wandering as well as noise in compression are also discussed. Baseline wandering provokes negative effects when using WWPRD index to guarantee quality because this index is normalized by the signal energy. Therefore, it is better to remove it before compression. On the other hand, noise causes an increase in signal energy provoking an artificial increase of the coded signal bit rate. Clinical validation by cardiologists showed that a WWPRD value of 10 preserves the signal quality and thus they recommend this value to be used in the compression system.

  14. A Simple Method for Guaranteeing ECG Quality in Real-Time Wavelet Lossy Coding

    Directory of Open Access Journals (Sweden)

    José García

    2007-01-01

    Full Text Available Guaranteeing ECG signal quality in wavelet lossy compression methods is essential for clinical acceptability of reconstructed signals. In this paper, we present a simple and efficient method for guaranteeing reconstruction quality measured using the new distortion index wavelet weighted PRD (WWPRD, which reflects in a more accurate way the real clinical distortion of the compressed signal. The method is based on the wavelet transform and its subsequent coding using the set partitioning in hierarchical trees (SPIHT algorithm. By thresholding the WWPRD in the wavelet transform domain, a very precise reconstruction error can be achieved thus enabling to obtain clinically useful reconstructed signals. Because of its computational efficiency, the method is suitable to work in a real-time operation, thus being very useful for real-time telecardiology systems. The method is extensively tested using two different ECG databases. Results led to an excellent conclusion: the method controls the quality in a very accurate way not only in mean value but also with a low-standard deviation. The effects of ECG baseline wandering as well as noise in compression are also discussed. Baseline wandering provokes negative effects when using WWPRD index to guarantee quality because this index is normalized by the signal energy. Therefore, it is better to remove it before compression. On the other hand, noise causes an increase in signal energy provoking an artificial increase of the coded signal bit rate. Clinical validation by cardiologists showed that a WWPRD value of 10% preserves the signal quality and thus they recommend this value to be used in the compression system.

  15. NMR methods for beer characterization and quality control.

    Science.gov (United States)

    Rodrigues, J E; Gil, A M

    2011-12-01

    The use of high-resolution NMR spectroscopy in the brewing industry is described; most studies having aimed at assessing the composition of beer and its raw materials and correlating it to a variety of quality parameters. First, the application of NMR to the qualitative characterization of beer is reviewed, addressing both targeted and untargeted methods and focusing on both beer extracts and direct beer analysis. A subsequent chapter addresses the NMR studies, which envisage the development of new rapid methods for beer analysis and quality control, such as site-specific natural fractionation-NMR and multivariate data analysis methods for marker search or rapid compound quantification. Finally, possible future perspectives toward a deeper and more complete understanding of beer and its brewing process are discussed. Copyright © 2012 John Wiley & Sons, Ltd.

  16. A QUALITY ASSESSMENT METHOD FOR 3D ROAD POLYGON OBJECTS

    Directory of Open Access Journals (Sweden)

    L. Gao

    2015-08-01

    Full Text Available With the development of the economy, the fast and accurate extraction of the city road is significant for GIS data collection and update, remote sensing images interpretation, mapping and spatial database updating etc. 3D GIS has attracted more and more attentions from academics, industries and governments with the increase of requirements for interoperability and integration of different sources of data. The quality of 3D geographic objects is very important for spatial analysis and decision-making. This paper presents a method for the quality assessment of the 3D road polygon objects which is created by integrating 2D Road Polygon data with LiDAR point cloud and other height information such as Spot Height data in Hong Kong Island. The quality of the created 3D road polygon data set is evaluated by the vertical accuracy, geometric and attribute accuracy, connectivity error, undulation error and completeness error and the final results are presented.

  17. Mobile vehicle road and weather observation quality check methods

    Science.gov (United States)

    Koller, Daniel Raymond

    data quality and accuracy, requiring the development of quality checks for mobile data collection. Using OBDII-equipped automobiles and mobile collection methods, we can begin to address issues of data quality by understanding, characterizing, and demonstrating the quality of mobile system observations from operational and research environments. Several forms of quality checking can be used, including range checks, Barnes spatial checks, comparing vehicle data to road weather models, and applying Clarus quality check methodologies and algorithms to mobile observations. Development of these quality checks can lead to the future integration of mobile data into the Clarus system, data implementation for improved forecasting, maintenance decision support, and traveler safety. This paper will discuss the benefits and challenges in mobile data collection, along with how the development and implementation of a system of quality checks will improve the quality and accuracy of mobile data collection.

  18. QUALITY ASSESSEMENT OF ANTE-NATAL CARE USING THE METHOD OF LOT QUALITY ASSURANCE SAMPLING

    Directory of Open Access Journals (Sweden)

    Sh. Salarilak

    1999-08-01

    Full Text Available To determine the coverage rate, timeliness and quality of ante-natal care in rural areas under the coverage of Health Houses in West Azerbaijan province, 30 Health Houses (HH were randomly selected out of 731 HH in the province. In each HH, using the method of Lot Quality Assurance Sampling (LQAS 28 women having recently born babies was selected. Data were collected using check-list for facilities, and questionnaires and forms to be completed from the files by interview. The study showed that the method of LQAS is quite effective for evaluation of this service at HH level. The weighted total coverage of ante-natal care was 46.2%. Quality of care was acceptable for 53.9% of mothers. The weighted average of time lines of care was 49.8%. Availability of facilities in delivery of this service was 100%, showing there was no short coming in this respect.

  19. Comparison of soil quality index using three methods.

    Directory of Open Access Journals (Sweden)

    Atanu Mukherjee

    Full Text Available Assessment of management-induced changes in soil quality is important to sustaining high crop yield. A large diversity of cultivated soils necessitate identification development of an appropriate soil quality index (SQI based on relative soil properties and crop yield. Whereas numerous attempts have been made to estimate SQI for major soils across the World, there is no standard method established and thus, a strong need exists for developing a user-friendly and credible SQI through comparison of various available methods. Therefore, the objective of this article is to compare three widely used methods to estimate SQI using the data collected from 72 soil samples from three on-farm study sites in Ohio. Additionally, challenge lies in establishing a correlation between crop yield versus SQI calculated either depth wise or in combination of soil layers as standard methodology is not yet available and was not given much attention to date. Predominant soils of the study included one organic (Mc, and two mineral (CrB, Ko soils. Three methods used to estimate SQI were: (i simple additive SQI (SQI-1, (ii weighted additive SQI (SQI-2, and (iii statistically modeled SQI (SQI-3 based on principal component analysis (PCA. The SQI varied between treatments and soil types and ranged between 0-0.9 (1 being the maximum SQI. In general, SQIs did not significantly differ at depths under any method suggesting that soil quality did not significantly differ for different depths at the studied sites. Additionally, data indicate that SQI-3 was most strongly correlated with crop yield, the correlation coefficient ranged between 0.74-0.78. All three SQIs were significantly correlated (r = 0.92-0.97 to each other and with crop yield (r = 0.65-0.79. Separate analyses by crop variety revealed that correlation was low indicating that some key aspects of soil quality related to crop response are important requirements for estimating SQI.

  20. Quality Index Method (QIM) scheme developed for farmed Atlantic salmon ( Salmo salar )

    DEFF Research Database (Denmark)

    Sveinsdóttir, K.; Hyldig, Grethe; Martinsdóttir, E.

    2003-01-01

    The aim of the study was to develop 'Quality Index Method (QIM) scheme for raw, farmed Atlantic salmon (Salmo salar) and to evaluate the scheme. in a shelf life study. QIM is based on the evaluation of key parameters in the deterioration of seafood's. Demerit points are assigned to selected...... parameters according to their importance and a Quality Index (QI) is established by cumulating the resulting scores. The maximum storage time in ice was determined with Quantitative Descriptive Analysis (QDA) of the salmon after cooking and found to be 20-21 days. This was used as a reference to enable...... prediction of the remaining storage time of raw salmon in ice with QIM. The calculated QI evolved linearly with storage time in ice (QI=0.82x (days in ice)+0.18, R-2=0.97). Individual salmon varied in QI within each storage day. However, the multivariate analysis (PLS1) demonstrated that storage time could...

  1. A Method to Estimate Shear Quality Factor of Hard Rocks

    Science.gov (United States)

    Wang, Xin; Cai, Ming

    2017-07-01

    Attenuation has a large influence on ground motion intensity. Quality factors are used to measure wave attenuation in a medium and they are often difficult to estimate due to many factors such as the complex geology and underground mining environment. This study investigates the effect of attenuation on seismic wave propagation and ground motion using an advanced numerical tool—SPECFEM2D. A method, which uses numerical modeling and site-specific scaling laws, is proposed to estimate the shear quality factor of hard rocks in underground mines. In the numerical modeling, the seismic source is represented by a moment tensor model and the considered medium is isotropic and homogeneous. Peak particle velocities along the strongest wave motion direction are compared with that from a design scaling law. Based on the field data that were used to derive a semi-empirical design scaling law, it is demonstrated that a shear quality factor of 60 seems to be a representative for the hard rocks in deep mines to consider the attenuation effect of seismic wave propagation. Using the proposed method, reasonable shear quality factors of hard rocks can be obtained and this, in turn, will assist accurate ground motion determination for mine design.

  2. Aggregate Indices Method in Soil Quality Evaluation Using the Relative Soil Quality Index

    Directory of Open Access Journals (Sweden)

    Ho Ngoc Pham

    2015-01-01

    Full Text Available This paper presents a new approach to assess the soil quality by aggregate indices using the Relative Soil Quality Index (RSQI proposed by Ho Ngoc Pham. RSQI is integrated from the individual indices into a simple formula for overall assessment of the soil quality. RSQI is different from other approaches. Particularly, the individual indices and the weighting factors of Pham are calculated from the analytical laboratory data and the environmental standards, respectively, and not self-regulated as in methods of some other authors. In this paper, the authors applied the RSQI to assess the Soil Environmental Quality of rice intensive cultivation areas through a case study in Haiduong province in 2013. The RSQI is calculated for sampling points in 12 districts and simulated the Soil Environmental Quality on GIS map. The results show that the Soil Environmental Quality of rice intensive cultivation areas in Haiduong is predominantly divided into three levels: good, moderate, and poor. According to the report of General Statistics Office for Haiduong province, rice intensive cultivation areas in 2013 achieved a relatively high average rice yield of 5.90 tonnes per hectare; it means actual soil properties are in line with results of the research.

  3. Enabling Design

    Science.gov (United States)

    2009-05-21

    What are the Team Roles ? ................................................................................... 31  What Size Should the Team Be...will have to assess these considerations against the size, expertise required, and the specific analysis method desired. What are the Team Roles ? Roles...useful to organize the work. A Design Team would be characterized as a short- life organization.28 Design Team roles are established and defined casually

  4. A quantitative method for measuring the quality of history matches

    Energy Technology Data Exchange (ETDEWEB)

    Shaw, T.S. [Kerr-McGee Corp., Oklahoma City, OK (United States); Knapp, R.M. [Univ. of Oklahoma, Norman, OK (United States)

    1997-08-01

    History matching can be an efficient tool for reservoir characterization. A {open_quotes}good{close_quotes} history matching job can generate reliable reservoir parameters. However, reservoir engineers are often frustrated when they try to select a {open_quotes}better{close_quotes} match from a series of history matching runs. Without a quantitative measurement, it is always difficult to tell the difference between a {open_quotes}good{close_quotes} and a {open_quotes}better{close_quotes} matches. For this reason, we need a quantitative method for testing the quality of matches. This paper presents a method for such a purpose. The method uses three statistical indices to (1) test shape conformity, (2) examine bias errors, and (3) measure magnitude of deviation. The shape conformity test insures that the shape of a simulated curve matches that of a historical curve. Examining bias errors assures that model reservoir parameters have been calibrated to that of a real reservoir. Measuring the magnitude of deviation assures that the difference between the model and the real reservoir parameters is minimized. The method was first tested on a hypothetical model and then applied to published field studies. The results showed that the method can efficiently measure the quality of matches. It also showed that the method can serve as a diagnostic tool for calibrating reservoir parameters during history matching.

  5. Aircraft Transparency Optical Quality: New Methods of Measurement

    Science.gov (United States)

    1981-02-01

    AFAMRL.TR-1-21 X AIRCRAFT TRANSPARENCY OPTICAL QUALITY: NEW METHODS OF MEASUREMENT LOUIS V. GENCO , O.D., Lt. Colonel HARRY L. TASK, Ph.D. FEBRUARY...aircraft transparency with simple modifications of a positioning fixture ( Genco , 1979). DESIRABLE CHARACTERISTICS The ideal field evaluation unit for...34Windscreen Angular Deviation Measurement Device," U.S. Air Force Invention No. 13647, Patent Pending. Task, Harry L., Louis V. Genco , and Kenneth L. Smith

  6. Quality of Methods Reporting in Animal Models of Colitis

    Science.gov (United States)

    Bramhall, Michael; Flórez-Vargas, Oscar; Stevens, Robert; Brass, Andy

    2015-01-01

    Background: Current understanding of the onset of inflammatory bowel diseases relies heavily on data derived from animal models of colitis. However, the omission of information concerning the method used makes the interpretation of studies difficult or impossible. We assessed the current quality of methods reporting in 4 animal models of colitis that are used to inform clinical research into inflammatory bowel disease: dextran sulfate sodium, interleukin-10−/−, CD45RBhigh T cell transfer, and 2,4,6-trinitrobenzene sulfonic acid (TNBS). Methods: We performed a systematic review based on PRISMA guidelines, using a PubMed search (2000–2014) to obtain publications that used a microarray to describe gene expression in colitic tissue. Methods reporting quality was scored against a checklist of essential and desirable criteria. Results: Fifty-eight articles were identified and included in this review (29 dextran sulfate sodium, 15 interleukin-10−/−, 5 T cell transfer, and 16 TNBS; some articles use more than 1 colitis model). A mean of 81.7% (SD = ±7.038) of criteria were reported across all models. Only 1 of the 58 articles reported all essential criteria on our checklist. Animal age, gender, housing conditions, and mortality/morbidity were all poorly reported. Conclusions: Failure to include all essential criteria is a cause for concern; this failure can have large impact on the quality and replicability of published colitis experiments. We recommend adoption of our checklist as a requirement for publication to improve the quality, comparability, and standardization of colitis studies and will make interpretation and translation of data to human disease more reliable. PMID:25989337

  7. QUALITY IMPROVEMENT METHODS AND THEIR USAGE IN ALBANIAN PUBLIC UNIVERSITIES

    Directory of Open Access Journals (Sweden)

    Arjan QEFALIA

    2012-06-01

    Full Text Available Education and higher education in particular is one of strategic priorities for development, which guarantees progress. Its role is related to all characteristics of a society, and it undoubtedly constitutes one of the most important areas of life of a nation. It has stable and long-term impact on all aspects of activities related to people and their welfare. The challenge to be faced in the transition period requires that higher education in Albania to be developed, consolidated and follow the trend of higher education in developed countries. Quality itself and by using the continuous quality improvement methods by universities, it constitutes the basis for ensuring the success of the Albanian higher education institutions in the future.In this paper, through the use of literature, the questionnaires and interviews directed mainly to the professors / pedagogues working in Albanian public higher education institutions, the focus is to show the continuous quality improvement methods used by universities / faculties / departments, and to test the hypothesis: The use or not of the continuous improvement methods is dependent on the studies type (those higher education institutions that offer first cycle studies, first and second cycle studies, or first, second and third cycle studies that the higher education institution offers.

  8. Analysis and Comparison of Objective Methods for Image Quality Assessment

    Directory of Open Access Journals (Sweden)

    P. S. Babkin

    2014-01-01

    Full Text Available The purpose of this work is research and modification of the reference objective methods for image quality assessment. The ultimate goal is to obtain a modification of formal assessments that more closely corresponds to the subjective expert estimates (MOS.In considering the formal reference objective methods for image quality assessment we used the results of other authors, which offer results and comparative analyzes of the most effective algorithms. Based on these investigations we have chosen two of the most successful algorithm for which was made a further analysis in the MATLAB 7.8 R 2009 a (PQS and MSSSIM. The publication focuses on the features of the algorithms, which have great importance in practical implementation, but are insufficiently covered in the publications by other authors.In the implemented modification of the algorithm PQS boundary detector Kirsch was replaced by the boundary detector Canny. Further experiments were carried out according to the method of the ITU-R VT.500-13 (01/2012 using monochrome images treated with different types of filters (should be emphasized that an objective assessment of image quality PQS is applicable only to monochrome images. Images were obtained with a thermal imaging surveillance system. The experimental results proved the effectiveness of this modification.In the specialized literature in the field of formal to evaluation methods pictures, this type of modification was not mentioned.The method described in the publication can be applied to various practical implementations of digital image processing.Advisability and effectiveness of using the modified method of PQS to assess the structural differences between the images are shown in the article and this will be used in solving the problems of identification and automatic control.

  9. Study on quality control method for compound Shanzha Granules

    Institute of Scientific and Technical Information of China (English)

    付延伟; 程艳芹

    2015-01-01

    Objective:To establish the quality standard of Compound Shanzha Granules. Methods:Crataegi Fructus and Cassiae Semen were identified by TLC. The contents of Autrantio- obtusin and Chrysophanol in Cassiae Semen were determined by HPLC. Results:The relevant spots on TLC plates were clear by the blank reference. The contents showed good linearitis in the range of 0.0357~0.3570μg for Autrantio- obtusin and 0.0520~0.5200μg for Chrysophanol.Conclusions:The method are simple, accurate and reproducible.

  10. A solution quality assessment method for swarm intelligence optimization algorithms.

    Science.gov (United States)

    Zhang, Zhaojun; Wang, Gai-Ge; Zou, Kuansheng; Zhang, Jianhua

    2014-01-01

    Nowadays, swarm intelligence optimization has become an important optimization tool and wildly used in many fields of application. In contrast to many successful applications, the theoretical foundation is rather weak. Therefore, there are still many problems to be solved. One problem is how to quantify the performance of algorithm in finite time, that is, how to evaluate the solution quality got by algorithm for practical problems. It greatly limits the application in practical problems. A solution quality assessment method for intelligent optimization is proposed in this paper. It is an experimental analysis method based on the analysis of search space and characteristic of algorithm itself. Instead of "value performance," the "ordinal performance" is used as evaluation criteria in this method. The feasible solutions were clustered according to distance to divide solution samples into several parts. Then, solution space and "good enough" set can be decomposed based on the clustering results. Last, using relative knowledge of statistics, the evaluation result can be got. To validate the proposed method, some intelligent algorithms such as ant colony optimization (ACO), particle swarm optimization (PSO), and artificial fish swarm algorithm (AFS) were taken to solve traveling salesman problem. Computational results indicate the feasibility of proposed method.

  11. Improved statistical method for temperature and salinity quality control

    Science.gov (United States)

    Gourrion, Jérôme; Szekely, Tanguy

    2017-04-01

    Climate research and Ocean monitoring benefit from the continuous development of global in-situ hydrographic networks in the last decades. Apart from the increasing volume of observations available on a large range of temporal and spatial scales, a critical aspect concerns the ability to constantly improve the quality of the datasets. In the context of the Coriolis Dataset for ReAnalysis (CORA) version 4.2, a new quality control method based on a local comparison to historical extreme values ever observed is developed, implemented and validated. Temperature, salinity and potential density validity intervals are directly estimated from minimum and maximum values from an historical reference dataset, rather than from traditional mean and standard deviation estimates. Such an approach avoids strong statistical assumptions on the data distributions such as unimodality, absence of skewness and spatially homogeneous kurtosis. As a new feature, it also allows addressing simultaneously the two main objectives of an automatic quality control strategy, i.e. maximizing the number of good detections while minimizing the number of false alarms. The reference dataset is presently built from the fusion of 1) all ARGO profiles up to late 2015, 2) 3 historical CTD datasets and 3) the Sea Mammals CTD profiles from the MEOP database. All datasets are extensively and manually quality controlled. In this communication, the latest method validation results are also presented. The method has already been implemented in the latest version of the delayed-time CMEMS in-situ dataset and will be deployed soon in the equivalent near-real time products.

  12. INNOVATIVE USE OF QUALITY MANAGEMENT METHODS FOR PRODUCT IMPROVEMENT

    Directory of Open Access Journals (Sweden)

    Katarzyna MIDOR

    2016-10-01

    Full Text Available Organisations constantly look for new, innovative solutions and methods which could be used to improve their efficiency and increase the quality of their products. Identifying the causes for returns is an important issue for modern compa-nies, as returns are the cause for the increase in production costs and, most importantly, the loss of credibility in the eyes of the client. Therefore, for the company to be able to sustain or strengthen its position on the market, it has to follow the rules of quality management. Especially important is the rule of constant improvement. This rule is primarily connected with preventing errors and defects from occurring at all the stages of the production process. To achieve that, one must, among other things, use quality management tools. The article presents an analysis of causes for returns of a vibrating screen produced by a company which manufactures machinery and equipment for the extractive industry, using quality management tools such as the Ishikawa diagram and Pareto analysis. The analysis allowed for the identifi-cation of the causes of client returns which could not be previously identified, and proposing solutions for them.

  13. Determination of waterscape beauties through visual quality assessment method.

    Science.gov (United States)

    Bulut, Zohre; Yilmaz, Hasan

    2009-07-01

    Besides being an indispensable life element, water is also in the first rows among the most important landscape elements that have the visual reserve value in both natural and cultural environments. In this study, the aim was to present suggestions about the use of waterscapes in landscape design and planning attempts by determining the water types bearing high visual reserve values among different types of waterscapes bearing high visual reserve values. The visual quality assessment method was used in this study. One hundred and twenty eight university students ranked the six waterscapes in a visual quality survey. The results showed that urban waterscape scenery [visual quality point (VQP) = 6.0391], was the most preferred category, whereas, river scenery (VQP = 3.5547) was the least preferred. The second preferred waterscape was waterfall (in rural landscape) scenery (VQP = 5.8594) and the third was standing water scenery (SWS; VQP = 5.3672). The relationships between landscape parameters and visual quality of landscape indicated that vividness and fascinaty parameters had a significant relation with preference. Some suggestions were made regarding the use of wa terscapes visual value in planning and designing of the landscape.

  14. Reconstruction of a high-quality metabolic model enables the identification of gene overexpression targets for enhanced antibiotic production in Streptomyces coelicolor A3(2).

    Science.gov (United States)

    Kim, Minsuk; Sang Yi, Jeong; Kim, Joonwon; Kim, Ji-Nu; Kim, Min Woo; Kim, Byung-Gee

    2014-09-01

    Streptomycetes are industrially and pharmaceutically important bacteria that produce a variety of secondary metabolites including antibiotics. Streptomycetes have a complex metabolic network responsible for the production of secondary metabolites and the utilization of organic residues present in soil. In this study, we reconstructed a high-quality metabolic model for Streptomyces coelicolor A3(2), designated iMK1208, in order to understand and engineer the metabolism of this model species. In comparison to iIB711, the previous metabolic model for S. coelicolor, the predictive power of iMK1208 was enhanced by the recent insights that enabled the incorporation of an updated biomass equation, stoichiometric matrix, and energetic parameters. iMK1208 was validated by comparing predictions with the experimental data for growth capability in various growth media. Furthermore, we applied a strain-design algorithm, flux scanning based on enforced objective flux (FSEOF), to iMK1208 for actinorhodin overproduction. FSEOF results identified not only previously known gene overexpression targets such as actII-ORF4 and acetyl-CoA carboxylase, but also novel targets such as branched-chain α-keto acid dehydrogenase (BCDH). We constructed and evaluated the BCDH overexpression mutant, which showed a 52-fold increase in actinorhodin production, validating the prediction power of iMK1208. Hence iMK1208 was shown to be a useful and valuable framework for studying the biotechnologically important Streptomyces species using the principles of systems biology and metabolic engineering.

  15. A GPS-Based Control Method for Load Sharing and Power Quality Improvement in Microgrids

    DEFF Research Database (Denmark)

    Golsorkhi, Mohammad; Lu, Dylan; Savaghebi, Mehdi;

    2016-01-01

    This paper proposes a novel control method for accurate sharing of load current among the Distributed Energy Resources (DER) and high power quality operating in islanded ac microgrids. This control scheme is based on hierarchical structure comprising of decentralized primary controllers and a cen....... The secondary controller produces compensation signals at fundamental and dominant harmonics to improve the voltage quality at a sensitive load bus. Experimental results are presented to validate the efficacy of the proposed method.......This paper proposes a novel control method for accurate sharing of load current among the Distributed Energy Resources (DER) and high power quality operating in islanded ac microgrids. This control scheme is based on hierarchical structure comprising of decentralized primary controllers......-I) droop characteristic. The droop coefficient, which acts as a virtual resistance, is adaptively changed as a function of peak current. This strategy not only simplifies the control design but also enables faster dynamics and higher accuracy of current sharing especially at high loading conditions...

  16. Determining the Most Appropriate Classification Methods for Water Quality

    Science.gov (United States)

    Gürsoy, Önder

    2016-10-01

    Assessing water resources’ quality and also monitoring them have attracted lots of attention in the recent years. Remote sensing has been growing widely in the last decade and its resources are very usable when it comes to water resources management. In this study, by using remote sensing technology, satellite images that have 350 to 1050 nanometres wavelength band sensors are used to determine the quality of the Kizilirmak River's water. Through the river's resources, ground based spectral measurements are made to identify the quality differences of the water at the test spots that have been determined before. In this context at Imranli, where the river contacts civilization for the first time, which is located in Sivas city of Turkey, samples are gathered in order to do ground based spectroradiometer measurements. These samples are gathered simultaneously with the image acquiring time of CHRIS Proba satellite. Spectral signatures that are obtained from ground measurements are used as reference data in order to classify CHRIS Proba satellite's hyperspectral images over the study area. Satellite images are classified based on Chemical Oxygen Demand (COD), Turbidity and Electrical Conductivity (EC) attributes. As a result, interpretations obtained from classified CHRIS Proba satellite hyperspectral images of the study area are presented. Spectras are readied for Matched Filtering and Spectral Angle Mapper methods for determining the best classification method.

  17. A unified method of inspection and quality control

    Directory of Open Access Journals (Sweden)

    P.V. Krishna Iyer

    1958-01-01

    Full Text Available It has been shown earlier that the mean and range charts used for S.Q.C. can be replaced by a single chart showing the largest and smallest values of samples taken from the machine at regular intervals. This chart designated as L-S chart has been found to be economical and efficient in many respects. The present paper shows that by modifying the sampling procedure, the S.Q.C. chart, besides providing information on the machine setting, tool wearing etc. for controlling the quality of the products collected during sampling intervals and thus enables us to dispense with 100 percent stage inspection which is in practice in the ordnance factories. The modification consists in taking one or two jobs from the machine at regular intervals and another four jobs at random from the products manufactured during every interval. The samples so selected are plotted on a chart against the specification limits. The collections during the different intervals will be accepted if all the four jobs are within the specification limits; otherwise screening will be done. Condition of the machine is judged mainly from the jobs taken from it. The experimental investigations conducted at Gun and Shell Factory, Cossipore show that this procedure works as effectively as the L-S chart and cent per cent inspection

  18. Effect of bread dough mixing method on rye bread quality

    Directory of Open Access Journals (Sweden)

    Đukić Dragutin A.

    2014-01-01

    Full Text Available The objective of this study was to evaluate the effect of sourdough (indirect bread dough mixing method on the quality of rye/wheat bread (TYPE 500 wheat flour and whole grain rye flour - 60:40 and determine its advantages over the straight dough method. Three bread dough mixing methods were used: I - indirect bread dough mixing using flour scalding; II - indirect bread dough mixing without flour scalding; III - straight dough mixing. The study involved the monitoring of the following: microbial characterristics of the flour and dough (yeasts and lactic acid bacteria and of the bread (presence of Enterobacteriaceae, yeasts and moulds; chemical properties of the dough and the bread (pH and degree of acidity; organoleptic attributes of bread (volume, porosity according to Dallman, crumb elasticity, pore structure fineness, bread crumb score, external appearance, crumb appearance, flavour of both the crust and the crumb. The results showed the highest counts of lactic acid bacteria and yeasts in the indirect bread dough mixing method using rye flour scalding. The rye/wheat bread made with sourdough had a mild sourish flavour, an intense aroma, a prolonged shelf life, and reduced crumbliness. The study suggests that the technological process of sourdough-type rye/wheat bread making is an important requirement in improving bread quality and assortment that can be used in any bakery facility.[ Projekat Ministarstva nauke Republike Srbije, br. TR 31057 i br. III 46009

  19. Development of quality-by-design analytical methods.

    Science.gov (United States)

    Vogt, Frederick G; Kord, Alireza S

    2011-03-01

    Quality-by-design (QbD) is a systematic approach to drug development, which begins with predefined objectives, and uses science and risk management approaches to gain product and process understanding and ultimately process control. The concept of QbD can be extended to analytical methods. QbD mandates the definition of a goal for the method, and emphasizes thorough evaluation and scouting of alternative methods in a systematic way to obtain optimal method performance. Candidate methods are then carefully assessed in a structured manner for risks, and are challenged to determine if robustness and ruggedness criteria are satisfied. As a result of these studies, the method performance can be understood and improved if necessary, and a control strategy can be defined to manage risk and ensure the method performs as desired when validated and deployed. In this review, the current state of analytical QbD in the industry is detailed with examples of the application of analytical QbD principles to a range of analytical methods, including high-performance liquid chromatography, Karl Fischer titration for moisture content, vibrational spectroscopy for chemical identification, quantitative color measurement, and trace analysis for genotoxic impurities.

  20. Evaluation of ride quality prediction methods for operational military helicopters

    Science.gov (United States)

    Leatherwood, J. D.; Clevenson, S. A.; Hollenbaugh, D. D.

    1984-01-01

    The results of a simulator study conducted to compare and validate various ride quality prediction methods for use in assessing passenger/crew ride comfort within helicopters are presented. Included are results quantifying 35 helicopter pilots' discomfort responses to helicopter interior noise and vibration typical of routine flights, assessment of various ride quality metrics including the NASA ride comfort model, and examination of possible criteria approaches. Results of the study indicated that crew discomfort results from a complex interaction between vibration and interior noise. Overall measures such as weighted or unweighted root-mean-square acceleration level and A-weighted noise level were not good predictors of discomfort. Accurate prediction required a metric incorporating the interactive effects of both noise and vibration. The best metric for predicting crew comfort to the combined noise and vibration environment was the NASA discomfort index.

  1. The “curved lead pathway” method to enable a single lead to reach any two intracranial targets

    Science.gov (United States)

    Ding, Chen-Yu; Yu, Liang-Hong; Lin, Yuan-Xiang; Chen, Fan; Lin, Zhang-Ya; Kang, De-Zhi

    2017-01-01

    Deep brain stimulation is an effective way to treat movement disorders, and a powerful research tool for exploring brain functions. This report proposes a “curved lead pathway” method for lead implantation, such that a single lead can reach in sequence to any two intracranial targets. A new type of stereotaxic system for implanting a curved lead to the brain of human/primates was designed, the auxiliary device needed for this method to be used in rat/mouse was fabricated and verified in rat, and the Excel algorithm used for automatically calculating the necessary parameters was implemented. This “curved lead pathway” method of lead implantation may complement the current method, make lead implantation for multiple targets more convenient, and expand the experimental techniques of brain function research.

  2. Project types of business process management: Towards a scenario structure to enable situational method engineering for business process management

    OpenAIRE

    Bucher, Tobias; Winter, Robert

    2009-01-01

    Purpose – The purpose of this paper is to explore project types (PTs) of business process management (BPM). PTs are a key concept to describe development situations in situational method engineering (SME). SME acts on the assumption that generic methods need to be adapted to the specifics of the development situation in which they are to be applied. Design/methodology/approach – The paper draws on results from an empirical analysis directed at the identification of design factors of...

  3. Designing a Broadband Pump for High-Quality Micro-Lasers via Modified Net Radiation Method

    Science.gov (United States)

    Nechayev, Sergey; Reusswig, Philip D.; Baldo, Marc A.; Rotschild, Carmel

    2016-12-01

    High-quality micro-lasers are key ingredients in non-linear optics, communication, sensing and low-threshold solar-pumped lasers. However, such micro-lasers exhibit negligible absorption of free-space broadband pump light. Recently, this limitation was lifted by cascade energy transfer, in which the absorption and quality factor are modulated with wavelength, enabling non-resonant pumping of high-quality micro-lasers and solar-pumped laser to operate at record low solar concentration. Here, we present a generic theoretical framework for modeling the absorption, emission and energy transfer of incoherent radiation between cascade sensitizer and laser gain media. Our model is based on linear equations of the modified net radiation method and is therefore robust, fast converging and has low complexity. We apply this formalism to compute the optimal parameters of low-threshold solar-pumped lasers. It is revealed that the interplay between the absorption and self-absorption of such lasers defines the optimal pump absorption below the maximal value, which is in contrast to conventional lasers for which full pump absorption is desired. Numerical results are compared to experimental data on a sensitized Nd3+:YAG cavity, and quantitative agreement with theoretical models is found. Our work modularizes the gain and sensitizing components and paves the way for the optimal design of broadband-pumped high-quality micro-lasers and efficient solar-pumped lasers.

  4. CHOREOGRAPHIC METHODS FOR CREATING NOVEL, HIGH QUALITY DANCE

    Directory of Open Access Journals (Sweden)

    David Kirsh

    2016-02-01

    Full Text Available We undertook a detailed ethnographic study of the dance creation process of a noted choreographer and his distinguished troupe. All choreographer dancer interactions were videoed, the choreographer and dancers were interviewed extensively each day, as well as other observations and tests performed. The choreographer used three main methods to produce high quality and novel content: showing, making-on, and tasking. We present, analyze and evaluate these methods, and show how these approaches allow the choreographer to increase the creative output of the dancers and him. His methods, although designed for dance, apply more generally to other creative endeavors, especially where brainstorming is involved, and where the creative process is distributed over many individuals. His approach is also a case study in multi-modal direction, owing to the range of mechanisms he uses to communicate and direct.

  5. Method for effectively utilizing tunable one-pump fiber parametric wavelength converters as an enabling device for WDM routers.

    Science.gov (United States)

    Cui, Sheng; Liu, Deming; Wang, Ying; Tu, Feng

    2009-02-02

    In this paper a method is proposed to maximize the bandwidth of the WDM router based on one-pump fiber parametric wavelength converters. It is proved that for such converters there exists an optimum signal (idler) frequency at which the output (input) tuning range can be maximized. Analytical expressions of the optimum frequency and the maximal tuning range are deduced. Then a two-stage bidirectional wavelength conversion method is proposed. With this method the bandwidth of the WDM router based on such a converter can be significantly improved compared to the one-stage ones by 252% if ordinary highly nonlinear fibers are used or 390% if fibers with optimal fourth order dispersion are used.

  6. Six Forms of Variety in Students' Moral Reasoning: An Age-Old Distinction Enabling New Methods and Findings

    Science.gov (United States)

    Backman, Ylva; Gardelli, Viktor

    2015-01-01

    In this study, the age-old distinction between decision method and criterion of rightness, commonly employed in normative ethics, was used to attain a detailed understanding of inter- and intrapersonal variety in students' moral reasoning. A total of 24 Swedish students, 12-15 years of age, were interviewed. Inter- and intrapersonal varieties in…

  7. Meat Quality of Chicken Breast Subjected to Different Thawing Methods

    Directory of Open Access Journals (Sweden)

    MR Oliveira

    2015-06-01

    Full Text Available Freezing is one of the methods to preserve and guarantee the quality of meat until it reaches the consumer. Even though freezing is classified as a mild form of preservation, it causes meat changes resulting from the formation of ice crystals that subsequently affect the tenderness and functionality of meat. The aim of this study was to evaluate the physicochemical and structural characteristics of chicken half breast submitted to fast freezing (-36 °C for 2 hours and thawed by five different methods (under refrigeration, in a microwave, in a oven with air circulation, placed in cold water, or at room temperature. After thawing, the following parameters were evaluated: moisture content, drip loss (syneresis, water activity (aw, and shear force. Samples were also histologically evaluated by light microscopy. The results indicated that, despite being submitted to fast freezing, thawing affected (p <0.05 most of the physicochemical and structural properties of the meat, except for aw. Thawing in cold water (packed in low-density polyethylene bags and placed in cold water at approximately 10 °C for 2 hours and 15 minutes presented the best results due to lesser damage to the cell structure, as shown by the lower drip loss, higher moisture content, and greater tenderness of the samples compared to those thawed using the other methods. Histological examination showed that muscle fiber structural features and organization were maintained. Thawing at low temperatures seems to cause less damage to the meat structure and allows maintaining of its properties. It was concluded that the meat quality is not related only with the freezing method, but also with the method and conditions used in thawing.

  8. Total Bolus Extraction Method Improves Arterial Image Quality in Dynamic CTAs Derived from Whole-Brain CTP Data

    Directory of Open Access Journals (Sweden)

    Elyas Ghariq

    2014-01-01

    Full Text Available Background and Purposes. The 320-detector row CT scanner enables visualization of whole-brain hemodynamic information (dynamic CT angiography (CTA derived from CT perfusion scans. However, arterial image quality in dynamic CTA (dCTA is inferior to arterial image quality in standard CTA. This study evaluates whether the arterial image quality can be improved by using a total bolus extraction (ToBE method. Materials and Methods. DCTAs of 15 patients, who presented with signs of acute cerebral ischemia, were derived from 320-slice CT perfusion scans using both the standard subtraction method and the proposed ToBE method. Two neurointerventionalists blinded to the scan type scored the arterial image quality on a 5-point scale in the 4D dCTAs in consensus. Arteries were divided into four categories: (I large extradural, (II intradural (large, medium, and small, (III communicating arteries, and (IV cerebellar and ophthalmic arteries. Results. Quality of extradural and intradural arteries was significantly higher in the ToBE dCTAs than in the standard dCTAs (extradural P=0.001, large intradural P<0.001, medium intradural P<0.001, and small intradural P<0.001. Conclusion. The 4D dCTAs derived with the total bolus extraction (ToBE method provide hemodynamic information combined with improved arterial image quality as compared to standard 4D dCTAs.

  9. METHOD OF IMAGE QUALITY ENHANCEMENT FOR SPACE OBJECTS

    Directory of Open Access Journals (Sweden)

    D. S. Korshunov

    2014-07-01

    Full Text Available The paper deals with an approach for image quality improvement of the space objects in the visible range of electromagnetic wave spectrum. The proposed method is based on the joint taking into account of both the motion velocity of the space supervisory apparatus and a space object observed in the near-earth space when the time of photo-detector exposure is chosen. The timing of exposure is carried out by light-signal characteristics, which determines the optimal value of the charge package formed in the charge-coupled device being irradiated. Thus, the parameters of onboard observation equipment can be selected, which provides space images suitable for interpretation. The linear resolving capacity is used as quality indicator for space images, giving a complete picture for the image contrast and geometric properties of the object on the photo. Observation scenario modeling of the space object, done by sputnik-inspector, has shown the possibility of increasing the linear resolution up to10% - 20% or up to 40% - 50% depending on the non-complanarity angle at the movement along orbits. The proposed approach to the increase of photographs quality provides getting sharp and highcontrast images of space objects by the optical-electronic equipment of the space-based remote sensing. The usage of these images makes it possible to detect in time the space technology failures, which are the result of its exploitation in the nearearth space. The proposed method can be also applied at the stage of space systems design for optical-electronic surveillance in computer models used for facilities assessment of the shooting equipment information tract.

  10. Authentication of food allergen quality by physicochemical and immunological methods

    DEFF Research Database (Denmark)

    Sancho, A I; Hoffmann-Sommergruber, K; Alessandri, S

    2010-01-01

    Purified allergens are required to detect cross-contamination with other allergenic foods and to understand allergen interaction with other components of the food matrix. Pure allergens are also used for the diagnosis and treatment of food allergies. For example, serological methods are being...... developed to improve the quality of diagnosis, and to reduce the need for food challenge tests. In addition, recombinant allergens are being evaluated as candidate vaccines for safe and efficacious specific immunotherapy. Pure allergens are indispensable as reference materials for the calibration...... and standardization of methods between different laboratories and operators for risk assessment in the food industry. Therefore, there is a need for well-defined purified food allergens. In this context, a panel of 46 food allergens from plant and animal sources has been purified, from either the food sources...

  11. Quality control methods for KOOS operational sea surface temperature products

    Institute of Scientific and Technical Information of China (English)

    YANG Chansu; KIM Sunhwa

    2016-01-01

    Sea surface temperature SST obtained from the initial version of the Korea Operational Oceanographic System (KOOS) SST satellite have low accuracy during summer and daytime. This is attributed to the diurnal warming effect. Error estimation of SST data must be carried out to use the real-time forecasting numerical model of the KOOS. This study suggests two quality control methods for the KOOS SST system. To minimize the diurnal warming effect, SSTs of areas where wind speed is higher than 5 m/s were used. Depending on the wind threshold value, KOOS SST data for August 2014 were reduced by 0.15°C. Errors in SST data are considered to be a combination of random, sampling, and bias errors. To estimate bias error, the standard deviation of bias between KOOS SSTs and climatology SSTs were used. KOOS SST data yielded an analysis error standard deviation value similar to OSTIA and NOAA NCDC (OISST) data. The KOOS SST shows lower random and sampling errors with increasing number of observations using six satellite datasets. In further studies, the proposed quality control methods for the KOOS SST system will be applied through more long-term case studies and comparisons with other SST systems.

  12. Selected Tools and Methods from Quality Management Field

    Directory of Open Access Journals (Sweden)

    Kateřina BRODECKÁ

    2009-06-01

    Full Text Available Following paper describes selected tools and methods from Quality management field and their practical applications on defined examples. Solved examples were elaborated in the form of electronic support. This in detail elaborated electronic support provides students opportunity to thoroughly practice specific issues, help them to prepare for exams and consequently will lead to education improvement. Especially students of combined study form will appreciate this support. The paper specifies project objectives, subjects that will be covered by mentioned support, target groups, structure and the way of elaboration of electronic exercise book in view. The emphasis is not only on manual solution of selected examples that may help students to understand the principles and relationships, but also on solving and results interpreting of selected examples using software support. Statistic software Statgraphics Plus v 5.0 is used while working support, because it is free to use for all students of the faculty. Exemplary example from the subject Basic Statistical Methods of Quality Management is also part of this paper.

  13. Taming the Data Quality Dragon--A Theory and Method for Data Quality by Design.

    Science.gov (United States)

    Weber, Jens H; Price, Morgan; Davies, Iryna

    2015-01-01

    A lack of data quality (DQ) is often a significant inhibitor impeding the realization of cost and quality benefits expected from Clinical Information Systems (CIS). Attaining and sustaining DQ in CIS has been a multi-faceted and elusive goal. The current literature on DQ in health informatics mainly consists of empirical studies and practitioners' reports, but often lack a holistic approach to addressing DQ 'by design'. This paper seeks to present a general framework for clinical DQ, which blends foundational engineering theories with concepts and methods from health informatics. We define an architectural viewpoint for designing and reasoning about DQ. We introduce the notion of DQ Probes for monitoring and assuring DQ during system operation. The concepts presented have been validated in a real-world case study.

  14. Mapping socio-economic scenarios of land cover change: a GIS method to enable ecosystem service modelling.

    Science.gov (United States)

    Swetnam, R D; Fisher, B; Mbilinyi, B P; Munishi, P K T; Willcock, S; Ricketts, T; Mwakalila, S; Balmford, A; Burgess, N D; Marshall, A R; Lewis, S L

    2011-03-01

    We present a GIS method to interpret qualitatively expressed socio-economic scenarios in quantitative map-based terms. (i) We built scenarios using local stakeholders and experts to define how major land cover classes may change under different sets of drivers; (ii) we formalized these as spatially explicit rules, for example agriculture can only occur on certain soil types; (iii) we created a future land cover map which can then be used to model ecosystem services. We illustrate this for carbon storage in the Eastern Arc Mountains of Tanzania using two scenarios: the first based on sustainable development, the second based on 'business as usual' with continued forest-woodland degradation and poor protection of existing forest reserves. Between 2000 and 2025 4% of carbon stocks were lost under the first scenario compared to a loss of 41% of carbon stocks under the second scenario. Quantifying the impacts of differing future scenarios using the method we document here will be important if payments for ecosystem services are to be used to change policy in order to maintain critical ecosystem services.

  15. Quality by Design (QbD)-enabled development of aceclofenac loaded-nano structured lipid carriers (NLCs): An improved dermatokinetic profile for inflammatory disorder(s).

    Science.gov (United States)

    Garg, Neeraj K; Sharma, Gajanand; Singh, Bhupinder; Nirbhavane, Pradip; Tyagi, Rajeev K; Shukla, Rahul; Katare, O P

    2017-01-30

    Present study was designed to prepare and characterize aceclofenac loaded nanostructured lipid carriers (NLCs) employing Quality by Design (QbD)-oriented approach. The NLCs were evaluated for their transdermal penetration potential and stability. Aceclofenac loaded nanostructured lipid carriers (NLCs) were prepared & characterized, by employing Quality by Design (QbD)-oriented approach and further evaluated for transdermal penetration potential and stability. Different lipids and surfactants were chosen to prepare NLCs using microemulsion method as critical material attributes (CMAs). A 3(3) factorial design was used for optimization of NLCs, and evaluating them for different critical quality attributes (CQAs), viz. particle size, polydispersity index (PDI), zeta potential, in vitro drug release, entrapment efficiency. The effect of CMAs such as lipids, oil: lipid ratio and concentration of surfactants on CQAs viz. drug entrapment efficiency and particle size were systematically evaluated to optimize NLCs. The optimized NLCs were further incorporated into carbopol gel and characterized for texture and rheology profile followed by in vitro and in vivo evaluations. The optimized ACE-NLCs were found to be spherical, nanometric in size with higher drug loading and entrapment efficiency. Results of the in vitro drug release study showed that the developed formulation followed Korsmeyer-Peppas model showing Fickian diffusion. The release was biphasic i.e., initial burst release followed by sustained drug release upto 48h. The optimized NLCs-based gel formulation showed superior texture, rheological profile and showed better cell uptake efficiency on hyperkeratinocytic cells (HaCaT cell lines) with higher ex vivo skin permeability efficiency vis-à-vis marketed formulation. In conclusion, dermatokinetic modeling and pharmacodynamic study using carrageenan induced edema mice suggests that aceclofenac loaded NLCs hydrogel may provide a better delivery alternative to target

  16. Breaking the link between environmental degradation and oil palm expansion: a method for enabling sustainable oil palm expansion.

    Directory of Open Access Journals (Sweden)

    Hans Harmen Smit

    Full Text Available Land degradation is a global concern. In tropical areas it primarily concerns the conversion of forest into non-forest lands and the associated losses of environmental services. Defining such degradation is not straightforward hampering effective reduction in degradation and use of already degraded lands for more productive purposes. To facilitate the processes of avoided degradation and land rehabilitation, we have developed a methodology in which we have used international environmental and social sustainability standards to determine the suitability of lands for sustainable agricultural expansion. The method was developed and tested in one of the frontiers of agricultural expansion, West Kalimantan province in Indonesia. The focus was on oil palm expansion, which is considered as a major driver for deforestation in tropical regions globally. The results suggest that substantial changes in current land-use planning are necessary for most new plantations to comply with international sustainability standards. Through visualizing options for sustainable expansion with our methodology, we demonstrate that the link between oil palm expansion and degradation can be broken. Application of the methodology with criteria and thresholds similar to ours could help the Indonesian government and the industry to achieve its pro-growth, pro-job, pro-poor and pro-environment development goals. For sustainable agricultural production, context specific guidance has to be developed in areas suitable for expansion. Our methodology can serve as a template for designing such commodity and country specific tools and deliver such guidance.

  17. Breaking the link between environmental degradation and oil palm expansion: a method for enabling sustainable oil palm expansion.

    Science.gov (United States)

    Harmen Smit, Hans; Meijaard, Erik; van der Laan, Carina; Mantel, Stephan; Budiman, Arif; Verweij, Pita

    2013-01-01

    Land degradation is a global concern. In tropical areas it primarily concerns the conversion of forest into non-forest lands and the associated losses of environmental services. Defining such degradation is not straightforward hampering effective reduction in degradation and use of already degraded lands for more productive purposes. To facilitate the processes of avoided degradation and land rehabilitation, we have developed a methodology in which we have used international environmental and social sustainability standards to determine the suitability of lands for sustainable agricultural expansion. The method was developed and tested in one of the frontiers of agricultural expansion, West Kalimantan province in Indonesia. The focus was on oil palm expansion, which is considered as a major driver for deforestation in tropical regions globally. The results suggest that substantial changes in current land-use planning are necessary for most new plantations to comply with international sustainability standards. Through visualizing options for sustainable expansion with our methodology, we demonstrate that the link between oil palm expansion and degradation can be broken. Application of the methodology with criteria and thresholds similar to ours could help the Indonesian government and the industry to achieve its pro-growth, pro-job, pro-poor and pro-environment development goals. For sustainable agricultural production, context specific guidance has to be developed in areas suitable for expansion. Our methodology can serve as a template for designing such commodity and country specific tools and deliver such guidance.

  18. A quality control method enhancement concept-Continual improvement of regulatory approved QC methods.

    Science.gov (United States)

    Åsberg, Dennis; Nilsson, Mikael; Olsson, Susanne; Samuelsson, Jörgen; Svensson, Olof; Klick, Silke; Ennis, Julie; Butterworth, Paul; Watt, Denise; Iliadou, Stavroula; Karlsson, Angelica; Walker, Joanne T; Arnot, Kate; Ealer, Norb; Hernqvist, Kerstin; Svensson, Karin; Grinell, Ali; Quist, Per-Ola; Karlsson, Anders; Fornstedt, Torgny

    2016-09-10

    Quality Control methods (QC-methods) play an important role in the overall control strategy for drug manufacturing. However, efficient life-cycle management and continual improvement are hindered due to a variety of post-approval variation legislations across territories and a lack of harmonization of the requirements. As a result, many QC-methods fall behind the technical development. Developing the QC-method in accordance with the Quality by Design guidelines gives the possibility to do continual improvements inside the original Method Operable Design Region (MODR). However, often it is necessary to do changes outside the MODR, e.g. to incorporate new technology that was not available at the time the original method was development. Here, we present a method enhancement concept which allows minor adjustments, within the same measuring principle, outside the original MODR without interaction with regulatory agencies. The feasibility of the concept is illustrated by a case study of a QC-method based on HPLC, assumed to be developed before the introduction of UHPLC, where the switch from HPLC to UHPLC is necessary as a continual improvement strategy. The concept relies on the assumption that the System Suitability Test (SST) and failure modes are relevant for other conditions outside the MODR as well when the same measuring principle is used. It follows that it should be possible to move outside the MODR as long as the SST has passed. All minor modifications of the original, approved QC-method must be re-validated according to a template given in the original submission and a statistical equivalence should be shown between the original and modified QC-methods. To summarize, revalidation is handled within the pharmaceutical quality control system according to internal change control procedures, but without interaction with regulating agencies.

  19. Massive parallelization of a 3D finite difference electromagnetic forward solution using domain decomposition methods on multiple CUDA enabled GPUs

    Science.gov (United States)

    Schultz, A.

    2010-12-01

    3D forward solvers lie at the core of inverse formulations used to image the variation of electrical conductivity within the Earth's interior. This property is associated with variations in temperature, composition, phase, presence of volatiles, and in specific settings, the presence of groundwater, geothermal resources, oil/gas or minerals. The high cost of 3D solutions has been a stumbling block to wider adoption of 3D methods. Parallel algorithms for modeling frequency domain 3D EM problems have not achieved wide scale adoption, with emphasis on fairly coarse grained parallelism using MPI and similar approaches. The communications bandwidth as well as the latency required to send and receive network communication packets is a limiting factor in implementing fine grained parallel strategies, inhibiting wide adoption of these algorithms. Leading Graphics Processor Unit (GPU) companies now produce GPUs with hundreds of GPU processor cores per die. The footprint, in silicon, of the GPU's restricted instruction set is much smaller than the general purpose instruction set required of a CPU. Consequently, the density of processor cores on a GPU can be much greater than on a CPU. GPUs also have local memory, registers and high speed communication with host CPUs, usually through PCIe type interconnects. The extremely low cost and high computational power of GPUs provides the EM geophysics community with an opportunity to achieve fine grained (i.e. massive) parallelization of codes on low cost hardware. The current generation of GPUs (e.g. NVidia Fermi) provides 3 billion transistors per chip die, with nearly 500 processor cores and up to 6 GB of fast (DDR5) GPU memory. This latest generation of GPU supports fast hardware double precision (64 bit) floating point operations of the type required for frequency domain EM forward solutions. Each Fermi GPU board can sustain nearly 1 TFLOP in double precision, and multiple boards can be installed in the host computer system. We

  20. Assessing groundwater quality for irrigation using indicator kriging method

    Science.gov (United States)

    Delbari, Masoomeh; Amiri, Meysam; Motlagh, Masoud Bahraini

    2016-11-01

    One of the key parameters influencing sprinkler irrigation performance is water quality. In this study, the spatial variability of groundwater quality parameters (EC, SAR, Na+, Cl-, HCO3 - and pH) was investigated by geostatistical methods and the most suitable areas for implementation of sprinkler irrigation systems in terms of water quality are determined. The study was performed in Fasa county of Fars province using 91 water samples. Results indicated that all parameters are moderately to strongly spatially correlated over the study area. The spatial distribution of pH and HCO3 - was mapped using ordinary kriging. The probability of concentrations of EC, SAR, Na+ and Cl- exceeding a threshold limit in groundwater was obtained using indicator kriging (IK). The experimental indicator semivariograms were often fitted well by a spherical model for SAR, EC, Na+ and Cl-. For HCO3 - and pH, an exponential model was fitted to the experimental semivariograms. Probability maps showed that the risk of EC, SAR, Na+ and Cl- exceeding the given critical threshold is higher in lower half of the study area. The most proper agricultural lands for sprinkler irrigation implementation were identified by evaluating all probability maps. The suitable areas for sprinkler irrigation design were determined to be 25,240 hectares, which is about 34 percent of total agricultural lands and are located in northern and eastern parts. Overall the results of this study showed that IK is an appropriate approach for risk assessment of groundwater pollution, which is useful for a proper groundwater resources management.

  1. The History of Infant Formula: Quality, Safety, and Standard Methods.

    Science.gov (United States)

    Wargo, Wayne F

    2016-01-01

    Food-related laws and regulations have existed since ancient times. Egyptian scrolls prescribed the labeling needed for certain foods. In ancient Athens, beer and wines were inspected for purity and soundness, and the Romans had a well-organized state food control system to protect consumers from fraud or bad produce. In Europe during the Middle Ages, individual countries passed laws concerning the quality and safety of eggs, sausages, cheese, beer, wine, and bread; some of these laws still exist today. But more modern dietary guidelines and food regulations have their origins in the latter half of the 19th century when the first general food laws were adopted and basic food control systems were implemented to monitor compliance. Around this time, science and food chemistry began to provide the tools to determine "purity" of food based primarily on chemical composition and to determine whether it had been adulterated in any way. Since the key chemical components of mammalian milk were first understood, infant formulas have steadily advanced in complexity as manufacturers attempt to close the compositional gap with human breast milk. To verify these compositional innovations and ensure product quality and safety, infant formula has become one of the most regulated foods in the world. The present paper examines the historical development of nutritional alternatives to breastfeeding, focusing on efforts undertaken to ensure the quality and safety from antiquity to present day. The impact of commercial infant formulas on global regulations is addressed, along with the resulting need for harmonized, fit-for-purpose, voluntary consensus standard methods.

  2. A Parameterized Method for Air-Quality Diagnosis and Its Applications

    Directory of Open Access Journals (Sweden)

    J. Z. Wang

    2012-01-01

    Full Text Available A parameterized method is developed to diagnose the air quality in Beijing and other cities with an index termed (parameters linking air-quality to meteorological elements PLAM derived from a correlation between PM10 and relevant weather elements based on the data between 2000 and 2007. Key weather factors for diagnosing the air pollution intensity are identified and included in PLAM that include atmospheric condensation of water vapour, wet potential equivalent temperature, and wind velocity. It is found that the poor air quality days with elevated PM10 are usually associated with higher PLAM values, featuring higher temperature, humidity, lower wind velocity, and higher stability compared to the averaged values in the same period. Both 24 h and 72 h forecasts provided useful services for the day of the opening ceremony of the Beijing Olympic Games and subsequent sport events. A correlation coefficient of 0.82 was achieved between the forecasts and (air pollution index API and 0.59 between the forecasts and observed PM10, all reaching the significant level of 0.001, for the summer period. A correction factor was also introduced to enable the PLAM to diagnose the observed PM10 concentrations all year round.

  3. Designing a Broadband Pump for High-Quality Micro-Lasers via Modified Net Radiation Method

    CERN Document Server

    Nechayev, Sergey; Baldo, Marc A; Rotschild, Carmel

    2016-01-01

    High-quality micro-lasers are key ingredients in non-linear optics, communication, sensing and low-threshold solar-pumped lasers. However, such micro-lasers exhibit negligible absorption of free-space broadband pump light. Recently, this limitation was lifted by cascade energy transfer, in which the absorption and quality factor are modulated with wavelength, enabling non-resonant pumping of high-quality micro-lasers and solar-pumped laser to operate at record low solar concentration. Here, we present a generic theoretical framework for modeling the absorption, emission and energy transfer of incoherent radiation between cascade sensitizer and laser gain media. Our model is based on linear equations of the modified net radiation method and is therefore robust, fast converging and has low complexity. We apply this formalism to compute the optimal parameters of low-threshold solar-pumped lasers. It is revealed that the interplay between the absorption and self-absorption of such lasers defines the optimal pump ...

  4. Information quality for PPC: analysis of influence factors and diagnosis method proposal

    Directory of Open Access Journals (Sweden)

    Eduardo Belmonte Möller

    2013-03-01

    Full Text Available One of the most important problems that companies have to face for Production Planning and Control (PPC is the lack of Information Quality (IQ to support the decision making process. In this context, determining which factors affect the IQ necessary for PPC is a key issue. This paper presents a case study that analyzes the main influence factors on IQ. Furthermore, this paper proposes a method to perform diagnosis about these influence factors in companies. To analyze the IQ influence factors, a classification based on the sociotechnical approach was used and a set of matrixes that relate the IQ influence factors with the different functional areas that support the PPC were proposed. Results enable to identify which are the main factors and the functional areas and processes that can be improved to increase the IQ for PPC. This paper presents also practical results that show how to drive an IQ diagnosis.

  5. Methods for the Quality Control of Inactivated Poliovirus Vaccines.

    Science.gov (United States)

    Wilton, Thomas

    2016-01-01

    Inactivated poliovirus vaccine (IPV) plays an instrumental role in the Global Poliovirus Eradication Initiative (GPEI). The quality of IPV is controlled by assessment of the potency of vaccine batches. The potency of IPV can be assessed by both in vivo and in vitro methods. In vitro potency assessment is based upon the assessment of the quantity of the D-Antigen (D-Ag) units in an IPV. The D-Ag unit is used as a measure of potency as it is largely expressed on native infectious virions and is the protective immunogen. The most commonly used in vitro test is the indirect ELISA which is used to ensure consistency throughout production.A range of in vivo assays have been developed in monkeys, chicks, guinea pigs, mice, and rats to assess the potency of IPV. All are based on assessment of the neutralizing antibody titer within the sera of the respective animal model. The rat potency test has become the favored in vivo potency test as it shows minimal variation between laboratories and the antibody patterns of rats and humans are similar. With the development of transgenic mice expressing the human poliovirus receptor, immunization-challenge tests have been developed to assess the potency of IPVs. This chapter describes in detail the methodology of these three laboratory tests to assess the quality of IPVs.

  6. Collaborative Business Models for Exploration: - The Expansion of Public-Private Partnerships to Enable Exploration and Improve the Quality of Life on Earth

    Science.gov (United States)

    Davis, Jeffrey R.

    2012-01-01

    In May of 2007, The Space Life Sciences Strategy was published, launching a series of efforts aimed at driving human health and performance innovations that both meet space flight needs and benefit life on Earth. These efforts, led by the Space Life Science Directorate (SLSD) at the NASA Johnson Space Center, led to the development and implementation of the NASA Human Health and Performance Center (NHHPC) in October 2010. The NHHPC now has over 100 members including seven NASA centers; other federal agencies; some of the International Space Station partners; industry; academia and non-profits. The NHHPC seeks to share best practices, develop collaborative projects and experiment with open collaboration techniques such as crowdsourcing. Using this approach, the NHHPC collaborative projects are anticipated to be at the earliest possible stage of development utilizing the many possible public-private partnerships in this center. Two workshops have been successfully conducted in 2011 (January and October) with a third workshop planned for the spring of 2012. The challenges of space flight are similar in many respects to providing health care and environmental monitoring in challenging settings on the earth. These challenges to technology development include the need for low power consumption, low weight, in-situ analysis, operator independence (i.e., minimal training), robustness, and limited resupply or maintenance. When similar technology challenges are identified (such as the need to provide and monitor a safe water supply or develop a portable medical diagnostic device for remote use), opportunities arise for public-private partnerships to engage in co-creation of novel approaches for space exploration and health and environmental applications on earth. This approach can enable the use of shared resources to reduce costs, engage other organizations and the public in participatory exploration (solving real-world problems), and provide technologies with multiple uses

  7. The Method for Motivation by Quality Function Deployment (QFD

    Directory of Open Access Journals (Sweden)

    Akao Yoji

    2014-11-01

    Full Text Available This paper presented a study on proposing a method for motivation with the use of QFD. It was reported by three students who majored in MOT at Graduate School of Science and Engineering, Yamagata University in 2009. QFD has been widely used in manufacture and service industries for making improvement with the existing products and programs. However, in this study, QFD was not used in the sense of “activation” to improve motivation. Rather, it took the viewpoint of “what is required by customers”, the central theme QFD, to approach the problem. With reference to the process of knowledge conversion suggested by the SECI Model, the study operated with the basic principles and steps of QFD. In the paper, the major steps of QFD leading to setting quality planning were outlined and the implication of the study was discussed.

  8. Performance analysis, quality function deployment and structured methods

    Science.gov (United States)

    Maier, M. W.

    Quality function deployment, (QFD), an approach to synthesizing several elements of system modeling and design into a single unit, is presented. Behavioral, physical, and performance modeling are usually considered as separate aspects of system design without explicit linkages. Structured methodologies have developed linkages between behavioral and physical models before, but have not considered the integration of performance models. QFD integrates performance models with traditional structured models. In this method, performance requirements such as cost, weight, and detection range are partitioned into matrices. Partitioning is done by developing a performance model, preferably quantitative, for each requirement. The parameters of the model become the engineering objectives in a QFD analysis and the models are embedded in a spreadsheet version of the traditional QFD matrices. The performance model and its parameters are used to derive part of the functional model by recognizing that a given performance model implies some structure to the functionality of the system.

  9. Effect of Drying Method and Variety on Quality of Cassava Starch ...

    African Journals Online (AJOL)

    Effect of Drying Method and Variety on Quality of Cassava Starch Extracts. ... However, the quality of the starch obtained from these alternative drying methods needs to be investigated. ... EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT

  10. Methods and Techniques of Quality Management for ICT Audit Processes

    Directory of Open Access Journals (Sweden)

    Marius Popa

    2011-09-01

    Full Text Available In modern organizations, Information and Communication Technologies are used to support the organizations’ activities. To manage the quality of the organization processes, audit processes are implemented. Also, the audit processes can aim the quality of ICT systems themselves because their involvement in organization processes. The paper investigates the ways in which a quality management can be applied for audit processes in order to obtain a high level of quality for the audit recommendations.

  11. Methods and Techniques of Quality Management for ICT Audit Processes

    CERN Document Server

    Popa, Marius

    2012-01-01

    In modern organizations, Information and Communication Technologies are used to support the organizations' activities. To manage the quality of the organization processes, audit processes are implemented. Also, the audit processes can aim the quality of ICT systems themselves because their involvement in organization processes. The paper investigates the ways in which a quality management can be applied for audit processes in order to obtain a high level of quality for the audit recommendations.

  12. QUALITY CONTROL OF HAWTHORN TINCTURE BY HPTLC METHOD

    Directory of Open Access Journals (Sweden)

    Khokhlova KO

    2016-09-01

    Full Text Available Introduction. Hawthorn tincture is one of the most used herbal drugs at the domestic pharmaceutical market. According to the State register of drugs at the pharmaceutical market of Ukraine, there are 13 commercial offers of Hawthorn tincture from home-produced manufactures. The initial herbal raw materials for Hawthorn tincture are Hawthorn fruits, which are widespread at the territory of Ukraine. These are pharmacopoeial herbal raw material. Thus, 12 different species of Hawthorn fruits are included into monograph of Ukrainian State Pharmacopoeia (SPhU and State Pharmacopoeia of USSR XI ed. On the territory of Ukraine there are near 30 different species of Hawthorn, and the quantity of species is much arises due to its forms and hybrids. The ‘natural variability’ of bioactive substances of Hawthorn fruits of the same species and possibility of usage of many different species during manufacturing process of herbal drugs lead to the pitfalls in standardization of herbal drugs in general, and Hawthorn tincture particularly, and should be taken in mind while development of its quality control methods. For development of specific and reproducible identification method, it is necessary to ensure the number of parameters: usage of method and equipment that give reproducible results; big selections of different samples; rigorously observation of method’s procedure of implementation. The modern, automated HPTLC method of analysis was chosen for identification purpose. If standardize procedure and suitable equipment are used, the reproducible results of the method have to be obtained. The aim of this paper was development of HPTLC method for identification of Hawthorn tincture, which could be appropriated for stability study and establishment of its expire date. Materials and Methods. In research 13 samples of Hawthorn tinctures from 8 manufactures from Ukraine and Russia were analyzed. These samples were manufactured in 2010, 2014, 2015 years. The

  13. Comparison of Different Numerical Methods for Quality Factor Calculation of Nano and Micro Photonic Cavities

    DEFF Research Database (Denmark)

    Taghizadeh, Alireza; Mørk, Jesper; Chung, Il-Sug

    2014-01-01

    Four different numerical methods for calculating the quality factor and resonance wavelength of a nano or micro photonic cavity are compared. Good agreement was found for a wide range of quality factors. Advantages and limitations of the different methods are discussed.......Four different numerical methods for calculating the quality factor and resonance wavelength of a nano or micro photonic cavity are compared. Good agreement was found for a wide range of quality factors. Advantages and limitations of the different methods are discussed....

  14. GRADATION OF INDUSTRIAL PRODUCTS QUALITY ASSESSMENT METHODS ACCORDING TO RESULTS OBJECTIVITY DEGREE

    OpenAIRE

    Viorel Petrescu; Adrian Stancu

    2008-01-01

    This paper presents the main tendencies in which the product quality evaluation can be done, and five quality assessment methods of industrial products, namely: quality complex indicator, general point method, continuum model, subfeature model, customer satisfaction performance model and products quality deviation towards consumers’ needs model. The gradation criterion of these methods was the results objectivity degree. To gradate these methods, a research was conducted in Ploiesti city, whi...

  15. Postgraduate Education in Quality Improvement Methods: Initial Results of the Fellows' Applied Quality Training (FAQT) Curriculum.

    Science.gov (United States)

    Winchester, David E; Burkart, Thomas A; Choi, Calvin Y; McKillop, Matthew S; Beyth, Rebecca J; Dahm, Phillipp

    2016-06-01

    Training in quality improvement (QI) is a pillar of the next accreditation system of the Accreditation Committee on Graduate Medical Education and a growing expectation of physicians for maintenance of certification. Despite this, many postgraduate medical trainees are not receiving training in QI methods. We created the Fellows Applied Quality Training (FAQT) curriculum for cardiology fellows using both didactic and applied components with the goal of increasing confidence to participate in future QI projects. Fellows completed didactic training from the Institute for Healthcare Improvement's Open School and then designed and completed a project to improve quality of care or patient safety. Self-assessments were completed by the fellows before, during, and after the first year of the curriculum. The primary outcome for our curriculum was the median score reported by the fellows regarding their self-confidence to complete QI activities. Self-assessments were completed by 23 fellows. The majority of fellows (15 of 23, 65.2%) reported no prior formal QI training. Median score on baseline self-assessment was 3.0 (range, 1.85-4), which was significantly increased to 3.27 (range, 2.23-4; P = 0.004) on the final assessment. The distribution of scores reported by the fellows indicates that 30% were slightly confident at conducting QI activities on their own, which was reduced to 5% after completing the FAQT curriculum. An interim assessment was conducted after the fellows completed didactic training only; median scores were not different from the baseline (mean, 3.0; P = 0.51). After completion of the FAQT, cardiology fellows reported higher self-confidence to complete QI activities. The increase in self-confidence seemed to be limited to the applied component of the curriculum, with no significant change after the didactic component.

  16. Consistent data recording across a health system and web-enablement allow service quality comparisons: online data for commissioning dermatology services.

    Science.gov (United States)

    Dmitrieva, Olga; Michalakidis, Georgios; Mason, Aaron; Jones, Simon; Chan, Tom; de Lusignan, Simon

    2012-01-01

    A new distributed model of health care management is being introduced in England. Family practitioners have new responsibilities for the management of health care budgets and commissioning of services. There are national datasets available about health care providers and the geographical areas they serve. These data could be better used to assist the family practitioner turned health service commissioners. Unfortunately these data are not in a form that is readily usable by these fledgling family commissioning groups. We therefore Web enabled all the national hospital dermatology treatment data in England combining it with locality data to provide a smart commissioning tool for local communities. We used open-source software including the Ruby on Rails Web framework and MySQL. The system has a Web front-end, which uses hypertext markup language cascading style sheets (HTML/CSS) and JavaScript to deliver and present data provided by the database. A combination of advanced caching and schema structures allows for faster data retrieval on every execution. The system provides an intuitive environment for data analysis and processing across a large health system dataset. Web-enablement has enabled data about in patients, day cases and outpatients to be readily grouped, viewed, and linked to other data. The combination of web-enablement, consistent data collection from all providers; readily available locality data; and a registration based primary system enables the creation of data, which can be used to commission dermatology services in small areas. Standardized datasets collected across large health enterprises when web enabled can readily benchmark local services and inform commissioning decisions.

  17. Aquatic life water quality criteria derived via the UC Davis method: I. Organophosphate insecticides.

    Science.gov (United States)

    Palumbo, Amanda J; Tenbrook, Patti L; Fojut, Tessa L; Faria, Isabel R; Tjeerdema, Ronald S

    2012-01-01

    A new methodology for deriving freshwater aquatic life water quality criteria,developed by the University of California Davis, was used to derive criteria for three organophosphate insecticides. The UC Davis methodology resulted in similar criteria to other accepted methods, and incorporated new approaches that enable criteria generation in cases where the existing USEPA guidance cannot be used.Acute and chronic water quality criteria were derived for chlorpyrifos (10 and 10 ng/L, respectively), diazinon (200 and 70 ng/L, respectively), and malathion(170 and 28 ng/L, respectively). For acute criteria derivation, Burr Type III SSDs were fitted to the chlorpyrifos and diazinon acute toxicity data sets while an alternative assessment factor procedure was used for malathion because that acute data set did not contain adequate species diversity to use a distribution.ACRs were used to calculate chronic criteria because there was a dearth of chronic data in all cases, especially for malathion, for which there was a lack of paired acute and chronic invertebrate data. Another alternate procedure enabled calculation of the malathion chronic criterion by combining a default ratio with the experimentally derived ratios. A review of the diazinon chronic criterion found it to be under protective of cladoceran species, so a more protective criterion was calculated using a lower distributional estimate. The acute and chronic data sets were assembled using a transparent and consistent system for judging the relevance and reliability of studies, and the individual study review notes are included.The resulting criteria are unique in that they were reviewed to ensure particular protection of sensitive and threatened and endangered species, and mixture toxicity is incorporated into criteria compliance for all three compounds.For chlorpyrifos and diazinon, the UCDM generated criteria similar to the long-standing USEPA (1985) method, with less taxa requirements, a more statistically

  18. Methodical Grounds of Managing the Product Quality Control

    Directory of Open Access Journals (Sweden)

    Shapoval Olena A.

    2014-01-01

    Full Text Available The article analyses the modern state of products quality control management. It justifies a necessity of organisation of the quality control system under conditions of uninterrupted flow line production. It reveals problems connected with a low level of the products quality control management. It forms a set of factors of internal and external environments, which should be taken into account in the process of selection of a type of managerial actions by the products quality control. It considers specific features of identification of the most important factors at an enterprise on the basis of use of the matrix of strategic SWOT analysis. It offers a procedure of identification of a general assessment of factors of influence. It analyses a mechanism of use of main conceptual models, which reflect the system nature of quality management in an organisation – quality pyramids and quality loops. It proves a necessity of application of a principally new scheme of relations between the customer and enterprise, which envisages that requirements of the quality management system focus not on control and screening of semi-finished products, but on creation of conditions that exclude rejects. It considers the role of ISO 9000 in the system of quality management, which recommend the customers to make a preliminary assessment of activity of the producing enterprise.

  19. Benchmarking: a method for continuous quality improvement in health.

    Science.gov (United States)

    Ettorchi-Tardy, Amina; Levif, Marie; Michel, Philippe

    2012-05-01

    Benchmarking, a management approach for implementing best practices at best cost, is a recent concept in the healthcare system. The objectives of this paper are to better understand the concept and its evolution in the healthcare sector, to propose an operational definition, and to describe some French and international experiences of benchmarking in the healthcare sector. To this end, we reviewed the literature on this approach's emergence in the industrial sector, its evolution, its fields of application and examples of how it has been used in the healthcare sector. Benchmarking is often thought to consist simply of comparing indicators and is not perceived in its entirety, that is, as a tool based on voluntary and active collaboration among several organizations to create a spirit of competition and to apply best practices. The key feature of benchmarking is its integration within a comprehensive and participatory policy of continuous quality improvement (CQI). Conditions for successful benchmarking focus essentially on careful preparation of the process, monitoring of the relevant indicators, staff involvement and inter-organizational visits. Compared to methods previously implemented in France (CQI and collaborative projects), benchmarking has specific features that set it apart as a healthcare innovation. This is especially true for healthcare or medical-social organizations, as the principle of inter-organizational visiting is not part of their culture. Thus, this approach will need to be assessed for feasibility and acceptability before it is more widely promoted.

  20. Color management systems: methods and technologies for increased image quality

    Science.gov (United States)

    Caretti, Maria

    1997-02-01

    All the steps in the imaging chain -- from handling the originals in the prepress to outputting them on any device - - have to be well calibrated and adjusted to each other, in order to reproduce color images in a desktop environment as accurate as possible according to the original. Today most of the steps in the prepress production are digital and therefore it is realistic to believe that the color reproduction can be well controlled. This is true thanks to the last years development of fast, cost effective scanners, digital sources and digital proofing devices not the least. It is likely to believe that well defined tools and methods to control this imaging flow will lead to large cost and time savings as well as increased overall image quality. Until now, there has been a lack of good, reliable, easy-to- use systems (e.g. hardware, software, documentation, training and support) in an extent that has made them accessible to the large group of users of graphic arts production systems. This paper provides an overview of the existing solutions to manage colors in a digital pre-press environment. Their benefits and limitations are discussed as well as how they affect the production workflow and organization. The difference between a color controlled environment and one that is not is explained.

  1. Data quality assurance in monitoring of wastewater quality: Univariate on-line and off-line methods

    DEFF Research Database (Denmark)

    Alferes, J.; Poirier, P.; Lamaire-Chad, C.;

    To make water quality monitoring networks useful for practice, the automation of data collection and data validation still represents an important challenge. Efficient monitoring depends on careful quality control and quality assessment. With a practical orientation a data quality assurance...... procedure is presented that combines univariate off-line and on-line methods to assess water quality sensors and to detect and replace doubtful data. While the off-line concept uses control charts for quality control, the on-line methods aim at outlier and fault detection by using autoregressive models....... The proposed tools were successfully tested with data sets collected at the inlet of a primary clarifier,where probably the toughest measurement conditions are found in wastewater treatment plants....

  2. A Quality Assurance Method that Utilizes 3D Dosimetry and Facilitates Clinical Interpretation

    Energy Technology Data Exchange (ETDEWEB)

    Oldham, Mark, E-mail: mark.oldham@duke.edu [Radiation Oncology, Duke University Medical Center, Durham, North Carolina (United States); Thomas, Andrew; O' Daniel, Jennifer; Juang, Titania [Radiation Oncology, Duke University Medical Center, Durham, North Carolina (United States); Ibbott, Geoffrey [University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Adamovics, John [Rider University, Lawrenceville, New Jersey (United States); Kirkpatrick, John P. [Radiation Oncology, Duke University Medical Center, Durham, North Carolina (United States)

    2012-10-01

    Purpose: To demonstrate a new three-dimensional (3D) quality assurance (QA) method that provides comprehensive dosimetry verification and facilitates evaluation of the clinical significance of QA data acquired in a phantom. Also to apply the method to investigate the dosimetric efficacy of base-of-skull (BOS) intensity-modulated radiotherapy (IMRT) treatment. Methods and Materials: Two types of IMRT QA verification plans were created for 6 patients who received BOS IMRT. The first plan enabled conventional 2D planar IMRT QA using the Varian portal dosimetry system. The second plan enabled 3D verification using an anthropomorphic head phantom. In the latter, the 3D dose distribution was measured using the DLOS/Presage dosimetry system (DLOS = Duke Large-field-of-view Optical-CT System, Presage Heuris Pharma, Skillman, NJ), which yielded isotropic 2-mm data throughout the treated volume. In a novel step, measured 3D dose distributions were transformed back to the patient's CT to enable calculation of dose-volume histograms (DVH) and dose overlays. Measured and planned patient DVHs were compared to investigate clinical significance. Results: Close agreement between measured and calculated dose distributions was observed for all 6 cases. For gamma criteria of 3%, 2 mm, the mean passing rate for portal dosimetry was 96.8% (range, 92.0%-98.9%), compared to 94.9% (range, 90.1%-98.9%) for 3D. There was no clear correlation between 2D and 3D passing rates. Planned and measured dose distributions were evaluated on the patient's anatomy, using DVH and dose overlays. Minor deviations were detected, and the clinical significance of these are presented and discussed. Conclusions: Two advantages accrue to the methods presented here. First, treatment accuracy is evaluated throughout the whole treated volume, yielding comprehensive verification. Second, the clinical significance of any deviations can be assessed through the generation of DVH curves and dose overlays on

  3. Selective Whole-Genome Amplification Is a Robust Method That Enables Scalable Whole-Genome Sequencing of Plasmodium vivax from Unprocessed Clinical Samples

    Directory of Open Access Journals (Sweden)

    Annie N. Cowell

    2017-02-01

    Full Text Available Whole-genome sequencing (WGS of microbial pathogens from clinical samples is a highly sensitive tool used to gain a deeper understanding of the biology, epidemiology, and drug resistance mechanisms of many infections. However, WGS of organisms which exhibit low densities in their hosts is challenging due to high levels of host genomic DNA (gDNA, which leads to very low coverage of the microbial genome. WGS of Plasmodium vivax, the most widely distributed form of malaria, is especially difficult because of low parasite densities and the lack of an ex vivo culture system. Current techniques used to enrich P. vivax DNA from clinical samples require significant resources or are not consistently effective. Here, we demonstrate that selective whole-genome amplification (SWGA can enrich P. vivax gDNA from unprocessed human blood samples and dried blood spots for high-quality WGS, allowing genetic characterization of isolates that would otherwise have been prohibitively expensive or impossible to sequence. We achieved an average genome coverage of 24×, with up to 95% of the P. vivax core genome covered by ≥5 reads. The single-nucleotide polymorphism (SNP characteristics and drug resistance mutations seen were consistent with those of other P. vivax sequences from a similar region in Peru, demonstrating that SWGA produces high-quality sequences for downstream analysis. SWGA is a robust tool that will enable efficient, cost-effective WGS of P. vivax isolates from clinical samples that can be applied to other neglected microbial pathogens.

  4. Selective Whole-Genome Amplification Is a Robust Method That Enables Scalable Whole-Genome Sequencing of Plasmodium vivax from Unprocessed Clinical Samples

    Science.gov (United States)

    Loy, Dorothy E.; Sundararaman, Sesh A.; Valdivia, Hugo; Fisch, Kathleen; Lescano, Andres G.; Baldeviano, G. Christian; Durand, Salomon; Gerbasi, Vince; Sutherland, Colin J.; Nolder, Debbie; Vinetz, Joseph M.; Hahn, Beatrice H.

    2017-01-01

    ABSTRACT Whole-genome sequencing (WGS) of microbial pathogens from clinical samples is a highly sensitive tool used to gain a deeper understanding of the biology, epidemiology, and drug resistance mechanisms of many infections. However, WGS of organisms which exhibit low densities in their hosts is challenging due to high levels of host genomic DNA (gDNA), which leads to very low coverage of the microbial genome. WGS of Plasmodium vivax, the most widely distributed form of malaria, is especially difficult because of low parasite densities and the lack of an ex vivo culture system. Current techniques used to enrich P. vivax DNA from clinical samples require significant resources or are not consistently effective. Here, we demonstrate that selective whole-genome amplification (SWGA) can enrich P. vivax gDNA from unprocessed human blood samples and dried blood spots for high-quality WGS, allowing genetic characterization of isolates that would otherwise have been prohibitively expensive or impossible to sequence. We achieved an average genome coverage of 24×, with up to 95% of the P. vivax core genome covered by ≥5 reads. The single-nucleotide polymorphism (SNP) characteristics and drug resistance mutations seen were consistent with those of other P. vivax sequences from a similar region in Peru, demonstrating that SWGA produces high-quality sequences for downstream analysis. SWGA is a robust tool that will enable efficient, cost-effective WGS of P. vivax isolates from clinical samples that can be applied to other neglected microbial pathogens. PMID:28174312

  5. Data Mining Methods Applied to Flight Operations Quality Assurance Data: A Comparison to Standard Statistical Methods

    Science.gov (United States)

    Stolzer, Alan J.; Halford, Carl

    2007-01-01

    In a previous study, multiple regression techniques were applied to Flight Operations Quality Assurance-derived data to develop parsimonious model(s) for fuel consumption on the Boeing 757 airplane. The present study examined several data mining algorithms, including neural networks, on the fuel consumption problem and compared them to the multiple regression results obtained earlier. Using regression methods, parsimonious models were obtained that explained approximately 85% of the variation in fuel flow. In general data mining methods were more effective in predicting fuel consumption. Classification and Regression Tree methods reported correlation coefficients of .91 to .92, and General Linear Models and Multilayer Perceptron neural networks reported correlation coefficients of about .99. These data mining models show great promise for use in further examining large FOQA databases for operational and safety improvements.

  6. Source, Method, and Surmise: Quality of Life in History

    Science.gov (United States)

    Jordan, Thomas E.

    2009-01-01

    The purpose of the essay is to demonstrate that study of quality of life can explore eras before our own. There are caches of social data as early as the seventeenth century, and there were people who attempted to formulate social circumstances close to today's concepts of quality of life. Data from England and Ireland are presented and analyzed.

  7. Study on a Quality Evaluation Method for College English Classroom Teaching

    Directory of Open Access Journals (Sweden)

    Mao-hua Sun

    2017-07-01

    Full Text Available A quality evaluation method is an important means and the main basis on which to evaluate the college English classroom teaching quality of teachers. To overcome the one-sided subjectivity and resulting imprecision of the traditional classroom teaching quality evaluation method, a scientific and reasonable quality evaluation index system for college English classroom teaching is constructed. The fuzzy comprehensive evaluation method and the analytic hierarchy process method are combined to propose an improved multi-level fuzzy comprehensive evaluation model for obtaining a new college English classroom teaching quality evaluation method. In the proposed method, according to the fuzzy characteristics of a college English classroom teaching quality evaluation, the fuzzy comprehensive evaluation method is used to transform the qualitative evaluation indexes into limited quantitative evaluation indexes, then a judgment matrix is constructed to determine the weights among different levels by using the analytic hierarchy process method. Additionally, the college English classroom teaching quality is evaluated in detail. Finally, an actual case of college English classroom teaching is used to verify the effectiveness of the college English classroom teaching quality evaluation method. The results show that the proposed college English classroom teaching method can overcome the subjectivity and randomness shortcomings of the traditional classroom teaching quality evaluation methods, and improve the reliability, accuracy, and objectivity of fuzzy comprehensive evaluation. It is an effective method to evaluate college English classroom teaching quality.

  8. Numerical study for the calculation of computer-generated hologram in color holographic 3D projection enabled by modified wavefront recording plane method

    Science.gov (United States)

    Chang, Chenliang; Qi, Yijun; Wu, Jun; Yuan, Caojin; Nie, Shouping; Xia, Jun

    2017-03-01

    A method of calculating computer-generated hologram (CGH) for color holographic 3D projection is proposed. A color 3D object is decomposed into red, green and blue components. For each color component, a virtual wavefront recording plane (WRP) is established which is nonuniformly sampled according to the depth map of the 3D object. The hologram of each color component is calculated from the nonuniform sampled WRP using the shifted Fresnel diffraction algorithm. Finally three holograms of RGB components are encoded into one single CGH based on the multiplexing encoding method. The computational cost of CGH generation is reduced by converting diffraction calculation from huge 3D voxels to three 2D planar images. Numerical experimental results show that the CGH generated by our method is capable to project zoomable color 3D object with clear quality.

  9. Quality-driven multi-objective optimization of software architecture design : method, tool, and application

    NARCIS (Netherlands)

    Etemadi Idgahi (Etemaadi), Ramin

    2014-01-01

    Software architecting is a non-trivial and demanding task for software engineers to perform. The architecture is a key enabler for software systems. Besides being crucial for user functionality, the software architecture has deep impact on software qualities such as performance, safety, and cost.

  10. Quality-driven multi-objective optimization of software architecture design : method, tool, and application

    NARCIS (Netherlands)

    Etemadi Idgahi (Etemaadi), Ramin

    2014-01-01

    Software architecting is a non-trivial and demanding task for software engineers to perform. The architecture is a key enabler for software systems. Besides being crucial for user functionality, the software architecture has deep impact on software qualities such as performance, safety, and cost.

  11. Quality control methods in accelerometer data processing: identifying extreme counts.

    Directory of Open Access Journals (Sweden)

    Carly Rich

    Full Text Available BACKGROUND: Accelerometers are designed to measure plausible human activity, however extremely high count values (EHCV have been recorded in large-scale studies. Using population data, we develop methodological principles for establishing an EHCV threshold, propose a threshold to define EHCV in the ActiGraph GT1M, determine occurrences of EHCV in a large-scale study, identify device-specific error values, and investigate the influence of varying EHCV thresholds on daily vigorous PA (VPA. METHODS: We estimated quantiles to analyse the distribution of all accelerometer positive count values obtained from 9005 seven-year old children participating in the UK Millennium Cohort Study. A threshold to identify EHCV was derived by differentiating the quantile function. Data were screened for device-specific error count values and EHCV, and a sensitivity analysis conducted to compare daily VPA estimates using three approaches to accounting for EHCV. RESULTS: Using our proposed threshold of ≥ 11,715 counts/minute to identify EHCV, we found that only 0.7% of all non-zero counts measured in MCS children were EHCV; in 99.7% of these children, EHCV comprised < 1% of total non-zero counts. Only 11 MCS children (0.12% of sample returned accelerometers that contained negative counts; out of 237 such values, 211 counts were equal to -32,768 in one child. The medians of daily minutes spent in VPA obtained without excluding EHCV, and when using a higher threshold (≥19,442 counts/minute were, respectively, 6.2% and 4.6% higher than when using our threshold (6.5 minutes; p<0.0001. CONCLUSIONS: Quality control processes should be undertaken during accelerometer fieldwork and prior to analysing data to identify monitors recording error values and EHCV. The proposed threshold will improve the validity of VPA estimates in children's studies using the ActiGraph GT1M by ensuring only plausible data are analysed. These methods can be applied to define appropriate EHCV

  12. Method and tool for generating and managing image quality allocations through the design and development process

    Science.gov (United States)

    Sparks, Andrew W.; Olson, Craig; Theisen, Michael J.; Addiego, Chris J.; Hutchins, Tiffany G.; Goodman, Timothy D.

    2016-05-01

    Performance models for infrared imaging systems require image quality parameters; optical design engineers need image quality design goals; systems engineers develop image quality allocations to test imaging systems against. It is a challenge to maintain consistency and traceability amongst the various expressions of image quality. We present a method and parametric tool for generating and managing expressions of image quality during the system modeling, requirements specification, design, and testing phases of an imaging system design and development project.

  13. Water quality assessment in Qu River based on fuzzy water pollution index method.

    Science.gov (United States)

    Li, Ranran; Zou, Zhihong; An, Yan

    2016-12-01

    A fuzzy improved water pollution index was proposed based on fuzzy inference system and water pollution index. This method can not only give a comprehensive water quality rank, but also describe the water quality situation with a quantitative value, which is convenient for the water quality comparison between the same ranks. This proposed method is used to assess water quality of Qu River in Sichuan, China. Data used in the assessment were collected from four monitoring stations from 2006 to 2010. The assessment results show that Qu River water quality presents a downward trend and the overall water quality in 2010 is the worst. The spatial variation indicates that water quality of Nanbashequ section is the pessimal. For the sake of comparison, fuzzy comprehensive evaluation and grey relational method were also employed to assess water quality of Qu River. The comparisons of these three approaches' assessment results show that the proposed method is reliable.

  14. Heat-transfer-method-based cell culture quality assay through cell detection by surface imprinted polymers.

    Science.gov (United States)

    Eersels, Kasper; van Grinsven, Bart; Khorshid, Mehran; Somers, Veerle; Püttmann, Christiane; Stein, Christoph; Barth, Stefan; Diliën, Hanne; Bos, Gerard M J; Germeraad, Wilfred T V; Cleij, Thomas J; Thoelen, Ronald; De Ceuninck, Ward; Wagner, Patrick

    2015-02-17

    Previous work has indicated that surface imprinted polymers (SIPs) allow for highly specific cell detection through macromolecular cell imprints. The combination of SIPs with a heat-transfer-based read-out technique has led to the development of a selective, label-free, low-cost, and user-friendly cell detection assay. In this study, the breast cancer cell line ZR-75-1 is used to assess the potential of the platform for monitoring the quality of a cell culture in time. For this purpose, we show that the proposed methodology is able to discriminate between the original cell line (adherent growth, ZR-75-1a) and a descendant cell line (suspension growth, ZR-75-1s). Moreover, ZR-75-1a cells were cultured for a prolonged period of time and analyzed using the heat-transfer method (HTM) at regular time intervals. The results of these experiments demonstrate that the thermal resistance (Rth) signal decays after a certain number of cell culture passages. This can likely be attributed to a compromised quality of the cell culture due to cross-contamination with the ZR-75-1s cell line, a finding that was confirmed by classical STR DNA profiling. The cells do not express the same functional groups on their membrane, resulting in a weaker bond between cell and imprint, enabling cell removal by mechanical friction, provided by flushing the measuring chamber with buffer solution. These findings were further confirmed by HTM and illustrate that the biomimetic sensor platform can be used as an assay for monitoring the quality of cell cultures in time.

  15. Quality of experience advanced concepts, applications and methods

    CERN Document Server

    Raake, Alexander

    2014-01-01

    This pioneering book develops definitions and concepts related to Quality of Experience in the context of multimedia- and telecommunications-related applications, systems and services, and applies these to various fields of communication and media technologies. The editors bring together numerous key-protagonists of the new discipline “Quality of Experience” and combine the state-of-the-art knowledge in one single volume. 

  16. The study of surgical image quality evaluation system by subjective quality factor method

    Science.gov (United States)

    Zhang, Jian J.; Xuan, Jason R.; Yang, Xirong; Yu, Honggang; Koullick, Edouard

    2016-03-01

    GreenLightTM procedure is an effective and economical way of treatment of benign prostate hyperplasia (BPH); there are almost a million of patients treated with GreenLightTM worldwide. During the surgical procedure, the surgeon or physician will rely on the monitoring video system to survey and confirm the surgical progress. There are a few obstructions that could greatly affect the image quality of the monitoring video, like laser glare by the tissue and body fluid, air bubbles and debris generated by tissue evaporation, and bleeding, just to name a few. In order to improve the physician's visual experience of a laser surgical procedure, the system performance parameter related to image quality needs to be well defined. However, since image quality is the integrated set of perceptions of the overall degree of excellence of an image, or in other words, image quality is the perceptually weighted combination of significant attributes (contrast, graininess …) of an image when considered in its marketplace or application, there is no standard definition on overall image or video quality especially for the no-reference case (without a standard chart as reference). In this study, Subjective Quality Factor (SQF) and acutance are used for no-reference image quality evaluation. Basic image quality parameters, like sharpness, color accuracy, size of obstruction and transmission of obstruction, are used as subparameter to define the rating scale for image quality evaluation or comparison. Sample image groups were evaluated by human observers according to the rating scale. Surveys of physician groups were also conducted with lab generated sample videos. The study shows that human subjective perception is a trustworthy way of image quality evaluation. More systematic investigation on the relationship between video quality and image quality of each frame will be conducted as a future study.

  17. Enabling graphene nanoelectronics.

    Energy Technology Data Exchange (ETDEWEB)

    Pan, Wei; Ohta, Taisuke; Biedermann, Laura Butler; Gutierrez, Carlos; Nolen, C. M.; Howell, Stephen Wayne; Beechem Iii, Thomas Edwin; McCarty, Kevin F.; Ross, Anthony Joseph, III

    2011-09-01

    Recent work has shown that graphene, a 2D electronic material amenable to the planar semiconductor fabrication processing, possesses tunable electronic material properties potentially far superior to metals and other standard semiconductors. Despite its phenomenal electronic properties, focused research is still required to develop techniques for depositing and synthesizing graphene over large areas, thereby enabling the reproducible mass-fabrication of graphene-based devices. To address these issues, we combined an array of growth approaches and characterization resources to investigate several innovative and synergistic approaches for the synthesis of high quality graphene films on technologically relevant substrate (SiC and metals). Our work focused on developing the fundamental scientific understanding necessary to generate large-area graphene films that exhibit highly uniform electronic properties and record carrier mobility, as well as developing techniques to transfer graphene onto other substrates.

  18. Methods for quality-assurance review of water-quality data in New Jersey

    Science.gov (United States)

    Brown, G. Allan; Pustay, Edward A.; Gibs, Jacob

    2003-01-01

    This report is an instructional and reference manual that describes methods developed and used by the U.S. Geological Survey (USGS), New Jersey District, to assure the accuracy and precision of the results of analyses of surface- and ground-water samples received from analyzing laboratories and, ultimately, to ensure the integrity of water-quality data in USGS databases and published reports. A statistical-analysis computer program, COMP.PPL, is used to determine whether the values reported by the laboratories are internally consistent, whether they are reasonable when compared with values for samples previously collected at the same site, and whether they exceed applicable drinking-water regulations. The program output consists of three files -- QWREVIEW, QWOUTLIERS, and QWCALC. QWREVIEW presents the results of tests of chemical logic and shows values that exceed drinking-water regulations. QWOUTLIERS identifies values that fall outside the historical range of values for the site sampled. QWCALC shows values and calculations used for reference purposes.

  19. Applying Open Geospatial Consortium’s Sensor Web Enablement to Address Real-Time Oceanographic Data Quality, Secondary Data Use, and Long-Term Preservation

    Science.gov (United States)

    2010-06-01

    The MVCO is comprised of a shore station, a meteorological mast, a 12-m node, and an air -sea interaction tower (Fig. 1). Each of these components...USF COMPS), Grace Cartwright (VIMS) and Brenda Babin (LUMCON). Also, we wish to thank John Graybeal and Carlos Rueda , from the Marine Metadata...Bogden, E. Bridger, T. Cook, J. Graybeal, S. Haines, C. Rueda , and C. Waldmann, “Integrating QA/QC into Open Geospatial Consortium Sensor Web Enablement,” OceanObs’09, Community White Paper, accepted.

  20. An Immersed Boundary Method in WRF for High Resolution Urban Air Quality Modeling

    Science.gov (United States)

    Wiersema, D. J.; Lundquist, K. A.; Martien, P. T.; Rivard, T.; Chow, F. K.

    2013-12-01

    Urban air quality modeling at the neighborhood scale has potential to become an important tool for long term exposure studies, regulation, and urban planning. Current generation models for urban flow or air quality are limited by laborious mesh creation, terrain slope restrictions due to coordinate transformations, lack of atmospheric physics, and/or omission of regional meteorological effects. To avoid these limitations we have extended the functionality of an existing model, IBM-WRF, a modified version of the Weather Research and Forecasting model (WRF) which uses an immersed boundary method (IBM) (Lundquist et al. 2010, 2012). The immersed boundary method used in our model allows for the evaluation of flow over complex urban geometries including vertical surfaces, sharp corners, and local topographic variations. Lateral boundaries in IBM-WRF can be prescribed using output from the standard WRF model, allowing for realistic meteorological input. IBM-WRF is being used to investigate transport and trapping of vehicle emissions around a proposed affordable housing development located adjacent to a major freeway which transports 250,000+ vehicles per day. Urban topography is created using high-resolution airborne LIDAR building data combined with ground elevation data. Emission locations and strengths are assigned using data provided by the Bay Area Air Quality Management District. Development is underway to allow for meteorological input to be created using the WRF model configured to use nested domains. This will allow for synoptic scale phenomena to affect the neighborhood scale IBM-WRF domain, which has a horizontal resolution on the order of one meter. Initial results from IBM-WRF are presented here and will ultimately be used to assist planning efforts to reduce local air pollution exposure and minimize related associated adverse health effects. Lundquist, K., F. Chow, and J. Lundquist, 2010: An immersed boundary method for the weather research and forecasting

  1. Objective video quality assessment method for freeze distortion based on freeze aggregation

    Science.gov (United States)

    Watanabe, Keishiro; Okamoto, Jun; Kurita, Takaaki

    2006-01-01

    With the development of the broadband network, video communications such as videophone, video distribution, and IPTV services are beginning to become common. In order to provide these services appropriately, we must manage them based on subjective video quality, in addition to designing a network system based on it. Currently, subjective quality assessment is the main method used to quantify video quality. However, it is time-consuming and expensive. Therefore, we need an objective quality assessment technology that can estimate video quality from video characteristics effectively. Video degradation can be categorized into two types: spatial and temporal. Objective quality assessment methods for spatial degradation have been studied extensively, but methods for temporal degradation have hardly been examined even though it occurs frequently due to network degradation and has a large impact on subjective quality. In this paper, we propose an objective quality assessment method for temporal degradation. Our approach is to aggregate multiple freeze distortions into an equivalent freeze distortion and then derive the objective video quality from the equivalent freeze distortion. Specifically, our method considers the total length of all freeze distortions in a video sequence as the length of the equivalent single freeze distortion. In addition, we propose a method using the perceptual characteristics of short freeze distortions. We verified that our method can estimate the objective video quality well within the deviation of subjective video quality.

  2. Evaluating the quality of ground-based microwave radiometer measurements and retrievals using detrended fluctuation and spectral analysis methods

    CERN Document Server

    Ivanova, K; Shirer, H N; Ackerman, T P; Liljegren, J C; Ausloos, M

    2001-01-01

    Time series both of microwave radiometer brightness temperature measurements at 23.8 and 31.4 GHz and of retrievals of water vapor and liquid water path from these brightness temperatures are evaluated using the detrended fluctuation analysis method. As quantified by the parameter $\\alpha$, this method (i) enables identification of the time scales over which noise dominates the time series and (ii) characterizes the temporal range of correlations in the time series. The more common spectral analysis method is also used to assess the data and its results are compared with those from detrended fluctuation analysis method. The assumption that measurements should have certain scaling properties allows the quality of the measurements to be characterized. The additional assumption that the scaling properties of the measurements of an atmospheric quantity are preserved in a useful retrieval provides a means for evaluating the retrieval itself. Applying these two assumptions to microwave radiometer measurements and r...

  3. High oleic sunflower biodiesel: quality control and different purification methods

    Directory of Open Access Journals (Sweden)

    Pighinelli, Anna L.M.T.

    2011-06-01

    Full Text Available The objective of the present work is to evaluate the production of biodiesel using ethanol and sunflower oil. The extraction of the sunflower oil was evaluated first. An experimental design was used to estimate the influence of the independent variables grain temperature (25º to 110ºC and expeller rotation (85 to 119rpm on the crude oil. The best result obtained was 68.38%, achieved with a rotation from 100 to 115rpm, grain temperature ranging from 25º to 30ºC and moisture content of around 7%. The next study consisted of transesterification, evaluating the influence of the ethanol, oil molar ratio and the catalyst concentration (sodium methylate on the ester-rich phase yield. The highest yield was 98.39% obtained with a molar ratio of 9:1 and 3% catalyst. An experiment was then carried out on a small reactor and the biodiesel produced was purified by three different methods: acidified water, silica and distillation. The quality aspects of the purified biodiesel samples were evaluated according to the Brazilian specifications for biodiesel, and distillation was shown to be the best method of purification.

    El objetivo del presente trabajo es evaluar la producción de biodiesel usando etanol y aceite de girasol. La extracción del aceite de girasol fue evaluada primero. Un diseño experimental fue usado para estimar la influencia de las variables independientes: temperatura del grano (25º a 110ºC y rotación del expeller (85 a 119 rpm en la obtención del aceite crudo. El mejor resultado obtenido fue un 68,38%, conseguido con una rotación de 100 a 115 rpm, una temperatura del grano de 25º a 30ºC y un contenido de humedad de alrededor del 7%. El siguiente estudio mediante transesterificación, evaluó la influencia de la relación molar etanol: aceite y concentración de catalizador (metilato sódico en el rendimiento de la fase rica en esteres. El rendimiento más alto fue 98,39% obtenido con una relación molar de 9.1 y 3% de

  4. Peer Promotions as a Method to Identify Quality Content

    Science.gov (United States)

    Gunnarsson, Bjorn Levi; Alterman, Richard

    2014-01-01

    Promoting blog content is a social activity--a means of communicating one student's appreciation of another student's work. This article explores the feasibility of using student promotions of content, in a blogosphere, to identify quality content, and implications for students and instructors. We show that students actively and voluntarily…

  5. The quality of task times: A methods research

    NARCIS (Netherlands)

    Schilden, van der M.

    1996-01-01

    IMAG-DLO is faced with large demands for labor data in spite of limited research capacity. Consequently IMAG-DLO is greatly concerned for the efficiency of the methodology used in task time synthesis, with even greater concern for maintaining the quality of the estimates of task times. Much effort h

  6. The assessment of drinking water quality using zero unitarization method

    Directory of Open Access Journals (Sweden)

    Radzka Elżbieta

    2015-12-01

    Full Text Available The work is an attempt to assess piped water quality in four counties located in east central Poland. Piped water was analysed for three successive years in each county. Water samples were tested for the following physical and chemical parameters: turbidity, colour, conductivity, taste, odour, pH, nitrates (III, nitrates (V, iron and manganese. They were compared with the current standard values. Preliminary data analysis included an analysis of maximum and minimum values of physical and chemical parameters, and it revealed that turbidity, colour, iron and manganese contents exceeded the permissible standards in all the counties. Percentages of parameters exceedances and mean values of the exceedances were used to rank the counties in terms of water quality. The ranking was obtained by means of multidimensional comparative analysis. It was demonstrated that best quality water was supplied by Węgrów County water supply system which was followed by Mińsk Mazowiecki County. The third rank was assigned to Łosice County and the poorest quality water was found to be supplied by Siedlce County water supply system.

  7. A new method for the determination of water quality

    African Journals Online (AJOL)

    2010-12-13

    Dec 13, 2010 ... It is based on measuring the maximum absorbance of. L-ascorbic acid ... In solution, L-ascorbic acid absorbs UV light with a maximum absorption in the 246- ... and low). The quality of the solvent also influences the speed of.

  8. Real Time Quality Control Methods for Cued EMI Data Collection

    Science.gov (United States)

    2016-01-12

    stages as well as during the final demonstration of the technology. Thanks to Kevin Kingdon, Dave Lutes, and Barry Zelt (with Sky Research at the time...aforementioned feature quality metrics. The first example shows inversion results for data collected over a 60mm mortar at 30cm burial depth (Figure 6

  9. Why some do but most don't. Barriers and enablers to engaging low-income groups in physical activity programmes: a mixed methods study

    Directory of Open Access Journals (Sweden)

    Fox Kenneth R

    2011-06-01

    Full Text Available Abstract Background The beneficial effect of physical activity for the prevention of a range of chronic diseases is widely acknowledged. These chronic conditions are most pronounced in economically disadvantaged groups where physical activity levels are consistently lower, yet this group is particularly difficult to recruit and retain in physical activity programmes. This study examined the perceptions of participants, non-participants, and exercise leaders in a low-income area regarding barriers, motives, and enabling factors for organised physical activity with a view to improving recruitment and retention. Methods A mixed methods research approach was adopted to guide data collection and analysis. A survey, incorporating the Motivation for Physical Activity Measure - Revised (MPAM-R, was used to assess the motivations of 152 physical activity session participants in a highly deprived suburban neighbourhood. The MPAM-R data were analysed using t tests, analyses of variance to estimate age, body mass index, and activity mode differences and Pearson's correlation coefficient to address associations. Semi-structured interviews were also conducted with 33 local residents who did not participate in activity sessions and with 14 activity session leaders. All interviews were audio-taped, transcribed verbatim and analyzed using an inductive thematic approach. Results Participants reported cost, childcare, lack of time and low awareness as barriers to joining activity classes. The need for support, confidence and competence in order to take up activity was widely expressed, particularly among women. Once people are active, high levels of social interaction, interest and enjoyment are associated with improved levels of retention, with different types of physical activity scoring differently on these factors. Conclusions This study suggests that some factors such as cost, the fear of 'walking in alone', accessibility of facilities, and appropriate

  10. Quality control analytical methods: strategies to ensure a robust quality-control microbiology program.

    Science.gov (United States)

    Griffiths, Tricia; Connors, Anne

    2013-01-01

    As the regulatory environment for compounding pharmacies continues to evolve, facilities can take immediate steps to strengthen their quality-control microbiology and environmental monitoring programs. Robust programs that are timely, comprehensive, and effective will minimize risk and help support positive patient outcomes. This article provides a roadmap for putting in place a robust quality-control microbiology program in the face of United States Pharmacopeia Chapter 797 standards, and highlights several technologies for environmental monitoring that support a successful program.

  11. Developing a model of quality management methods and evaluating their effects on business performance

    NARCIS (Netherlands)

    Zhang, ZH

    2000-01-01

    From an extensive review of the total quality management (TQM) literature, a model of quality management methods (QMMs) was developed. The model has 83 QMMs which are categorized by the 11 TQM elements they primarily aim to improve. Ten manufacturing companies which were renowned for quality managem

  12. Developing a model of quality management methods and evaluating their effects on business performance

    NARCIS (Netherlands)

    Zhang, ZH

    2000-01-01

    From an extensive review of the total quality management (TQM) literature, a model of quality management methods (QMMs) was developed. The model has 83 QMMs which are categorized by the 11 TQM elements they primarily aim to improve. Ten manufacturing companies which were renowned for quality managem

  13. Developing a model of quality management methods and evaluating their effects on business performance

    NARCIS (Netherlands)

    Zhang, ZH

    From an extensive review of the total quality management (TQM) literature, a model of quality management methods (QMMs) was developed. The model has 83 QMMs which are categorized by the 11 TQM elements they primarily aim to improve. Ten manufacturing companies which were renowned for quality

  14. Study on Entropy Weight Coefficient Method and Application for Water Quality Evaluation

    Institute of Scientific and Technical Information of China (English)

    MEN Bao-hui; FU Qiang; ZHAO Xie-jing

    2004-01-01

    In order to evaluate the quality of water environment, the conception of entropy is applied in information science, and the entropy weight model is built to evaluate comprehensively water quality. The indexes weights of water quality are determined by value of entropy. This kind of method is applied on evaluating water quality in the new water to be built. The result shows that the water quality in it which supply water is between grade Ⅲ and Ⅳ, and the result is similar to that of gray related method.

  15. A New Method for Ride Quality Analysis of Vehicle

    Institute of Scientific and Technical Information of China (English)

    LIN Jian-hui; ZHANG Jie; GAO Yan; LI Tian-rui

    2006-01-01

    Current spectral analysis for evaluating the rail ride quality effectively is based on the sampling data at a uniform time interval, but the train is of fluctuation velocity in motion,which results in a non-uniform interval between consecutive sampling data. Therefore the accuracy of routine spectral analysis is in doubt when applying it in evaluating the rail ride quality. This paper presents a new way, namely, resampling with variable frequency to eliminate the influence of the train's uneven velocity. Its feature is that there is no need for precision measurement of the train's moving speed.Experiment results from the test-bed of rolling stock vibration show that it is valid.

  16. Application of quality-improvement methods in a community practice: the Sandhills Pediatrics Asthma Initiative.

    Science.gov (United States)

    Wroth, Thomas H; Boals, Joseph C

    2005-01-01

    This case study demonstrates the use of quality improvement methods to improve asthma care in a busy community practice. The practice used disease-management strategies, such as population identification, self-management education, and performance measurement and feedback. The practice then applied several practice-based quality improvement methods, such as PDSA cycles, to improve care. From 1998 to 2003, process measures, such as staging of asthmatics, use of long-term control medications, use of peak flow meters and spacers, and use of action plans, improved. There was also a substantial decrease in emergency department use and hospitalizations among patients with asthma. Although there have been several studies demonstrating the efficacy of disease management strategies, most lack generalizability to community practices. Often, interventions are so intensive and cumbersome, that they are unlikely to be replicated in primary care setting. Researchers have been unable to determine which components of the interventions are most effective and replicable. Furthermore, many studies of disease management strategies enroll participants who lack the co-morbidities seen in community practice. There are also few studies of disadvantaged populations that face other barriers to care, such as lack of transportation, poor access to specialists, and medical illiteracy. In this case study, there were several unique factors that enabled the practice to improve care for this population. The AccessCare case manager who worked with the practice not only provided data and feedback to the practice team, but also served as an improvement "coach," often pushing the team and facilitating many of the improvement efforts. AccessCare's approach is in contrast to many of the commercial disease management companies' "carve out" models that do not sufficiently involve providers or practices in their interventions. The other necessary ingredient for success in this project was organizational

  17. A comprehensive method for GNSS data quality determination to improve ionospheric data analysis.

    Science.gov (United States)

    Kim, Minchan; Seo, Jiwon; Lee, Jiyun

    2014-08-14

    Global Navigation Satellite Systems (GNSS) are now recognized as cost-effective tools for ionospheric studies by providing the global coverage through worldwide networks of GNSS stations. While GNSS networks continue to expand to improve the observability of the ionosphere, the amount of poor quality GNSS observation data is also increasing and the use of poor-quality GNSS data degrades the accuracy of ionospheric measurements. This paper develops a comprehensive method to determine the quality of GNSS observations for the purpose of ionospheric studies. The algorithms are designed especially to compute key GNSS data quality parameters which affect the quality of ionospheric product. The quality of data collected from the Continuously Operating Reference Stations (CORS) network in the conterminous United States (CONUS) is analyzed. The resulting quality varies widely, depending on each station and the data quality of individual stations persists for an extended time period. When compared to conventional methods, the quality parameters obtained from the proposed method have a stronger correlation with the quality of ionospheric data. The results suggest that a set of data quality parameters when used in combination can effectively select stations with high-quality GNSS data and improve the performance of ionospheric data analysis.

  18. Systems and methods for data quality control and cleansing

    Science.gov (United States)

    Wenzel, Michael; Boettcher, Andrew; Drees, Kirk; Kummer, James

    2016-05-31

    A method for detecting and cleansing suspect building automation system data is shown and described. The method includes using processing electronics to automatically determine which of a plurality of error detectors and which of a plurality of data cleansers to use with building automation system data. The method further includes using processing electronics to automatically detect errors in the data and cleanse the data using a subset of the error detectors and a subset of the cleansers.

  19. The Poka-Yoke method as an improving quality tool of operations in the process

    OpenAIRE

    M. Dudek-Burlikowska; D. Szewieczek

    2009-01-01

    Purpose: A new approach for the implementation of quality philosophy Zero Quality Defects with usage of the Poka-Yoke method in the polish organization has been presented.Design/methodology/approach: The possibility of usage of mistake proofing device is connected with monitoring and improvement of operations in the process.Findings: At the present time the organizations should implement quality tools, techniques, methods which support the prevention strategy and should pay attention to impro...

  20. 42 CFR 440.260 - Methods and standards to assure quality of services.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Methods and standards to assure quality of services. 440.260 Section 440.260 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH... and Limits Applicable to All Services § 440.260 Methods and standards to assure quality of...

  1. Porosity testing methods for the quality assessment of selective laser melted parts

    NARCIS (Netherlands)

    Wits, W.W.; Carmignato, S.; Zanini, F.; Vaneker, T.H.J.

    2016-01-01

    This study focuses on the comparison of porosity testing methods for the quality assessment of selective laser melted parts. Porosity is regarded as important quality indicator in metal additive manufacturing. Various destructive and non-destructive testing methods are compared, ranging from global

  2. IEEE 802154 and ZigBee as enabling technologies for low-power wireless systems with quality-of-service constraints

    CERN Document Server

    Tennina, Stefano; Daidone, Roberta; Alves, Mário; Jurčík, Petr; Severino, Ricardo; Tiloca, Marco; Hauer, Jan-Hinrich; Pereira, Nuno; Dini, Gianluca; Bouroche, Mélanie; Tovar, Eduardo

    2013-01-01

    This book outlines the most important characteristics of IEEE 802.15.4 and ZigBee and how they can be used to engineer Wireless Sensor Network (WSN) systems and applications, with a particular focus on Quality-of-Service (QoS) aspects. It starts by providing a snapshot of the most relevant features of these two protocols, identifying some gaps in the standard specifications. Then it describes several state-of-the-art open-source implementations, models and tools that have been designed by the authors and have been widely used by the international community. The book also outlines the fundamental performance limits of IEEE 802.15.4/ZigBee networks, based on well-sustained analytical, simulation and experimental models, including how to dimension such networks to optimize delay/energy trade-offs.

  3. Extension and Enhancement Methods for Setting Data Quality Objectives

    Energy Technology Data Exchange (ETDEWEB)

    D. Goodman

    2000-03-01

    The project developed statistical tools for the application of decision theory and operations research methods, including cost-benefit analysis, to the DQO process for environmental clean up. A pilot study was conducted, using these methods at the Hanford site, to estimate vadose zone contamination plumes under the SX tank farm, and to help plan further sampling.

  4. Mixed Methods in VET Research: Usage and Quality

    Science.gov (United States)

    Cameron, Roslyn

    2010-01-01

    Mixed methods had been heralded as the third methodological movement with several authorities from across an array of discipline fields contributing to a growing body of literature and theoretical developments. The discipline fields which are showing high levels of acceptance for mixed methods are those related to education, health and nursing,…

  5. Mission-Related Execution and Planning Through Quality of Service Methods

    Science.gov (United States)

    2010-06-01

    CORBA or a service-oriented architecture (SOA) solution can be deployed within each node of a system of systems and carry out many functions...management and monitoring of resource using solutions wrapped in CORBA . Providing infrastructure such as middleware provides some QoS solutions for...Dissemination (QED) Quality of Service Enabled Dissemination (QED) builds on previously developed QoS tools and entities as well as the CORBA -based middleware

  6. Evaluation of water quality using water quality index (WQI) method and GIS in Aksu River (SW-Turkey).

    Science.gov (United States)

    Şener, Şehnaz; Şener, Erhan; Davraz, Ayşen

    2017-04-15

    The aim of this study is evaluate water quality of the Aksu River, the main river recharging the Karacaören-1 Dam Lake and flowing approximately 145km from Isparta province to Mediterranean. Due to plan for obtaining drinking water from the Karacaören-1 Dam Lake for Antalya Province, this study has great importance. In this study, physical and chemical analyses of water samples taken from 21 locations (in October 2011 and May 2012, two periods) through flow path of the river were investigated. The analysis results were compared with maximum permissible limit values recommended by World Health Organization and Turkish drinking water standards. The water quality for drinking purpose was evaluated using the water quality index (WQI) method. The computed WQI values are between 35.6133 and 337.5198 in the study. The prepared WQI map shows that Karacaören-1 Dam Lake generally has good water quality. However, water quality is poor and very poor in the north and south of the river basin. The effects of punctual and diffuse pollutants dominate the water quality in these regions. Furthermore, the most effective water quality parameters are COD and Mg on the determination of WQI for the present study.

  7. Towards a standardized method of developing quality indicators for palliative care: protocol of the Quality indicators for Palliative Care (Q-PAC) study

    National Research Council Canada - National Science Library

    Leemans, Kathleen; Cohen, Joachim; Francke, Anneke L; Vander Stichele, Robert; Claessen, Susanne Jj; Van den Block, Lieve; Deliens, Luc

    2013-01-01

    .... In this Quality Indicators for Palliative Care study (Q-PAC study) we have applied a scientifically rigorous method to develop a comprehensive and valid quality indicator set which can contribute to a standardized method for use in other countries...

  8. A Review of Data Quality Assessment Methods for Public Health Information Systems

    Science.gov (United States)

    Chen, Hong; Hailey, David; Wang, Ning; Yu, Ping

    2014-01-01

    High quality data and effective data quality assessment are required for accurately evaluating the impact of public health interventions and measuring public health outcomes. Data, data use, and data collection process, as the three dimensions of data quality, all need to be assessed for overall data quality assessment. We reviewed current data quality assessment methods. The relevant study was identified in major databases and well-known institutional websites. We found the dimension of data was most frequently assessed. Completeness, accuracy, and timeliness were the three most-used attributes among a total of 49 attributes of data quality. The major quantitative assessment methods were descriptive surveys and data audits, whereas the common qualitative assessment methods were interview and documentation review. The limitations of the reviewed studies included inattentiveness to data use and data collection process, inconsistency in the definition of attributes of data quality, failure to address data users’ concerns and a lack of systematic procedures in data quality assessment. This review study is limited by the coverage of the databases and the breadth of public health information systems. Further research could develop consistent data quality definitions and attributes. More research efforts should be given to assess the quality of data use and the quality of data collection process. PMID:24830450

  9. A review of data quality assessment methods for public health information systems.

    Science.gov (United States)

    Chen, Hong; Hailey, David; Wang, Ning; Yu, Ping

    2014-05-14

    High quality data and effective data quality assessment are required for accurately evaluating the impact of public health interventions and measuring public health outcomes. Data, data use, and data collection process, as the three dimensions of data quality, all need to be assessed for overall data quality assessment. We reviewed current data quality assessment methods. The relevant study was identified in major databases and well-known institutional websites. We found the dimension of data was most frequently assessed. Completeness, accuracy, and timeliness were the three most-used attributes among a total of 49 attributes of data quality. The major quantitative assessment methods were descriptive surveys and data audits, whereas the common qualitative assessment methods were interview and documentation review. The limitations of the reviewed studies included inattentiveness to data use and data collection process, inconsistency in the definition of attributes of data quality, failure to address data users' concerns and a lack of systematic procedures in data quality assessment. This review study is limited by the coverage of the databases and the breadth of public health information systems. Further research could develop consistent data quality definitions and attributes. More research efforts should be given to assess the quality of data use and the quality of data collection process.

  10. Water quality evaluation based on improved fuzzy matter-element method

    Institute of Scientific and Technical Information of China (English)

    Dongjun Liu; Zhihong Zou

    2012-01-01

    For natural water,method of water quality evaluation based on improved fuzzy matter-element evaluation method is presented.Two important parts are improved,the weights determining and fuzzy membership functions.The coefficient of variation of each indicator is used to determine the weight instead of traditional calculating superscales method.On the other hand,fuzzy matter-elements are constructed,and normal membership degrees are used instead of traditional trapezoidal ones.The composite fuzzy matter-elements with associated coefficient are constructed through associated transformation.The levels of natural water quality are determined according to the principle of maximum correlation.The improved fuzzy matter-element evaluation method is applied to evaluate water quality of the Luokou mainstream estuary at the first ten weeks in 2011 with the coefficient of variation method determining the weights.Water quality of Luokou mainstream estuary is dropping from level Ⅰ to level Ⅱ.The results of the improved evaluation method are basically the same as the official water quality.The variation coefficient method can reduce the workload,and overcome the adverse effects from abnormal values,compared with the traditional calculating superscales method.The results of improved fuzzy matterelement evaluation method are more credible than the ones of the traditional evaluation method.The improved evaluation method can use information of monitoring data more scientifically and comprehensively,and broaden a new evaluation method for water quality assessment.

  11. Water quality: determination of dissolved oxygen : electrochemical probe method

    National Research Council Canada - National Science Library

    2012-01-01

    ISO 5814:2012 specifies an electrochemical method for the determination of dissolved oxygen in water by means of an electrochemical cell which is isolated from the sample by a gas permeable membrane...

  12. Orthology prediction methods: a quality assessment using curated protein families.

    Science.gov (United States)

    Trachana, Kalliopi; Larsson, Tomas A; Powell, Sean; Chen, Wei-Hua; Doerks, Tobias; Muller, Jean; Bork, Peer

    2011-10-01

    The increasing number of sequenced genomes has prompted the development of several automated orthology prediction methods. Tests to evaluate the accuracy of predictions and to explore biases caused by biological and technical factors are therefore required. We used 70 manually curated families to analyze the performance of five public methods in Metazoa. We analyzed the strengths and weaknesses of the methods and quantified the impact of biological and technical challenges. From the latter part of the analysis, genome annotation emerged as the largest single influencer, affecting up to 30% of the performance. Generally, most methods did well in assigning orthologous group but they failed to assign the exact number of genes for half of the groups. The publicly available benchmark set (http://eggnog.embl.de/orthobench/) should facilitate the improvement of current orthology assignment protocols, which is of utmost importance for many fields of biology and should be tackled by a broad scientific community. Copyright © 2011 WILEY Periodicals, Inc.

  13. Development and approbation methods of complex estimation of flexo extrusion packaging quality

    Directory of Open Access Journals (Sweden)

    Manakov Volodymyr

    2016-04-01

    Full Text Available The article considers the issues of quality control of tube packing. For determination of the quality level of the packing, printed by flexographic printing a complex method is used. This method allows to identify the most significant parameters, which influence the printing quality. The basic unit parameters are: dot gain, misalignment of colors, changing the overall contrast, deviation by color. Expert method, based on the survey of employees of printing companies who are professionals in the field of packaging and label flexographic printing, is used for determination of the weighting coefficients of quality indicators. Complex evaluation of printing quality allows to connect visual evaluation, instrumental, and physical indicators of tube packing quality.

  14. Assessment of AlSi21CuNi Alloy’s Quality with Use of ATND Method

    Directory of Open Access Journals (Sweden)

    Pezda J.

    2013-12-01

    Full Text Available Majority of combustion engines is produced (poured from Al-Si alloys with low thermal expansion coefficient, so called piston silumins. Hypereutectic alloys normally contain coarse, primary angular Si particles together with eutectic Si phase. The structure and mechanical properties of these alloys are highly dependent upon cooling rate, composition, modification and heat-treatment operations. In the paper one depicts use of the ATND method (thermal-voltage-derivative analysis and regression analysis to assessment of quality of the AlSi21CuNi alloy modified with Cu-P on stage of its preparation, in aspect of obtained mechanical properties (R0,02, Rm, A5, HB. Obtained dependencies enable prediction of mechanical properties of the investigated alloy in laboratory conditions, using values of characteristic points from curves of the ATND method.

  15. Predicting recreational water quality advisories: A comparison of statistical methods

    Science.gov (United States)

    Brooks, Wesley R.; Corsi, Steven R.; Fienen, Michael N.; Carvin, Rebecca B.

    2016-01-01

    Epidemiological studies indicate that fecal indicator bacteria (FIB) in beach water are associated with illnesses among people having contact with the water. In order to mitigate public health impacts, many beaches are posted with an advisory when the concentration of FIB exceeds a beach action value. The most commonly used method of measuring FIB concentration takes 18–24 h before returning a result. In order to avoid the 24 h lag, it has become common to ”nowcast” the FIB concentration using statistical regressions on environmental surrogate variables. Most commonly, nowcast models are estimated using ordinary least squares regression, but other regression methods from the statistical and machine learning literature are sometimes used. This study compares 14 regression methods across 7 Wisconsin beaches to identify which consistently produces the most accurate predictions. A random forest model is identified as the most accurate, followed by multiple regression fit using the adaptive LASSO.

  16. XFEL diffraction: developing processing methods to optimize data quality

    Energy Technology Data Exchange (ETDEWEB)

    Sauter, Nicholas K., E-mail: nksauter@lbl.gov [Lawrence Berkeley National Laboratory, Berkeley, CA 94720 (United States)

    2015-01-29

    Bragg spots recorded from a still crystal necessarily give partial measurements of the structure factor intensity. Correction to the full-spot equivalent, relying on both a physical model for crystal disorder and postrefinement of the crystal orientation, improves the electron density map in serial crystallography. Serial crystallography, using either femtosecond X-ray pulses from free-electron laser sources or short synchrotron-radiation exposures, has the potential to reveal metalloprotein structural details while minimizing damage processes. However, deriving a self-consistent set of Bragg intensities from numerous still-crystal exposures remains a difficult problem, with optimal protocols likely to be quite different from those well established for rotation photography. Here several data processing issues unique to serial crystallography are examined. It is found that the limiting resolution differs for each shot, an effect that is likely to be due to both the sample heterogeneity and pulse-to-pulse variation in experimental conditions. Shots with lower resolution limits produce lower-quality models for predicting Bragg spot positions during the integration step. Also, still shots by their nature record only partial measurements of the Bragg intensity. An approximate model that corrects to the full-spot equivalent (with the simplifying assumption that the X-rays are monochromatic) brings the distribution of intensities closer to that expected from an ideal crystal, and improves the sharpness of anomalous difference Fourier peaks indicating metal positions.

  17. Methods to improve biomass quality for thermal conversion

    NARCIS (Netherlands)

    Cardona Zea, D.A.; Hein, L.G.; Elbersen, H.W.; Poppens, R.P.; Bakker, R.R.C.

    2011-01-01

    The utilisation of biomass for thermal conversion present limitations in terms of the content of ash and inorganic minerals producing different problems in the combustion systems. Implementing some methods at the growing, harvesting and pre-processing phases upstream in the production chain, increas

  18. Smoothness Evaluation of Cotton Nonwovens Using Quality Energy Method

    Science.gov (United States)

    Nonwovens are finding enhanced use in next-to-skin application such as wipes. The global wipe industry is estimated somewhere between $6-8 billion. One important attributes of the wipes is its smoothness as it determines it end use applications. Although there are a number of methods and techniques ...

  19. Modern methods for the quality management of high-rate melt solidification

    Science.gov (United States)

    Vasiliev, V. A.; Odinokov, S. A.; Serov, M. M.

    2016-12-01

    The quality management of high-rate melt solidification needs combined solution obtained by methods and approaches adapted to a certain situation. Technological audit is recommended to estimate the possibilities of the process. Statistical methods are proposed with the choice of key parameters. Numerical methods, which can be used to perform simulation under multifactor technological conditions, and an increase in the quality of decisions are of particular importance.

  20. Development of Photogrammetric Methods of Stress Analysis and Quality Control

    CERN Document Server

    Kubik, D L; Kubik, Donna L.; Greenwood, John A.

    2003-01-01

    A photogrammetric method of stress analysis has been developed to test thin, nonstandard windows designed for hydrogen absorbers, major components of a muon cooling channel. The purpose of the absorber window tests is to demonstrate an understanding of the window behavior and strength as a function of applied pressure. This is done by comparing the deformation of the window, measured via photogrammetry, to the deformation predicted by finite element analysis (FEA). FEA analyses indicate a strong sensitivity of strain to the window thickness. Photogrammetric methods were chosen to measure the thickness of the window, thus providing data that are more accurate to the FEA. This, plus improvements made in hardware and testing procedures, resulted in a precision of 5 microns in all dimensions and substantial agreement with FEA predictions.

  1. Biological methods used to assess surface water quality

    Directory of Open Access Journals (Sweden)

    Szczerbiñska Natalia

    2015-12-01

    Full Text Available In accordance with the guidelines of the Water Framework Directive 2000/60 (WFD, both ecological and chemical statuses determine the assessment of surface waters. The profile of ecological status is based on the analysis of various biological components, and physicochemical and hydromorphological indicators complement this assessment. The aim of this article is to present the biological methods used in the assessment of water status with a special focus on bioassay, as well as to provide a review of methods of monitoring water status. Biological test methods include both biomonitoring and bioanalytics. Water biomonitoring is used to assess and forecast the status of water. These studies aim to collect data on water pollution and forecast its impact. Biomonitoring uses organisms which are characterized by particular vulnerability to contaminants. Bioindicator organisms are algae, fungi, bacteria, larval invertebrates, cyanobacteria, macroinvertebrates, and fish. Bioanalytics is based on the receptors of contaminants that can be biologically active substances. In bioanalytics, biosensors such as viruses, bacteria, antibodies, enzymes, and biotests are used to assess degrees of pollution.

  2. A DNA sequence alignment algorithm using quality information and a fuzzy inference method

    Institute of Scientific and Technical Information of China (English)

    Kwangbaek Kim; Minhwan Kim; Youngwoon Woo

    2008-01-01

    DNA sequence alignment algorithms in computational molecular biology have been improved by diverse methods.In this paper.We propose a DNA sequence alignment that Uses quality information and a fuzzy inference method developed based on the characteristics of DNA fragments and a fuzzy logic system in order to improve conventional DNA sequence alignment methods that uses DNA sequence quality information.In conventional algorithms.DNA sequence alignment scores are calculated by the global sequence alignment algorithm proposed by Needleman-Wunsch,which is established by using quality information of each DNA fragment.However,there may be errors in the process of calculating DNA sequence alignment scores when the quality of DNA fragment tips is low.because only the overall DNA sequence quality information are used.In our proposed method.an exact DNA sequence alignment can be achieved in spite of the low quality of DNA fragment tips by improvement of conventional algorithms using quality information.Mapping score parameters used to calculate DNA sequence alignment scores are dynamically adjusted by the fuzzy logic system utilizing lengths of DNA fragments and frequencies of low quality DNA bases in the fragments.From the experiments by applying real genome data of National Center for Bioteclmology Information,we could see that the proposed method is more efficient than conventional algorithms.

  3. Validity of Standard Measures of Family Planning Service Quality: Findings from the Simulated Client Method

    Science.gov (United States)

    Tumlinson, Katherine; Speizer, Ilene S.; Curtis, Sian L.; Pence, Brian W.

    2014-01-01

    Despite widespread endorsement within the field of international family planning regarding the importance of quality of care as a reproductive right, the field has yet to develop validated data collection instruments to accurately assess quality in terms of its public health importance. This study, conducted among 19 higher volume public and private facilities in Kisumu, Kenya, used the simulated client method to test the validity of three standard data collection instruments included in large-scale facility surveys: provider interviews, client interviews, and observation of client-provider interactions. Results found low specificity and positive predictive values in each of the three instruments for a number of quality indicators, suggesting that quality of care may be overestimated by traditional methods. Revised approaches to measuring family planning service quality may be needed to ensure accurate assessment of programs and to better inform quality improvement interventions. PMID:25469929

  4. Service quality under the perspective of SERVQUAL and SERVPERF methods: a bibliometric study

    Directory of Open Access Journals (Sweden)

    Luiz Felipe Vasconcelos de Faria

    2015-09-01

    Full Text Available This work aims to analyze the articles published in the international literature on service quality focusing on the SERVQUAL and SERVPERF methodologies, taking into account the publications’ evolution over time, the main authors, the main journals, the most cited papers, and older papers. The study also aims to identify which method is most commonly used for assessing service quality: SERVQUAL or SERVPERF? The ProQuest scientific database was used to conduct the analysis. The results show an increasing number of publications, especially after 2009. SERVQUAL was seen to be the main method for assessing service quality. In addition, a selection of the main papers related to service quality is presented. The study proves to be important in providing a starting point for the bibliography on service quality for both methods.

  5. How to Measure Quality of Service Using Unstructured Data Analysis: A General Method Design

    Directory of Open Access Journals (Sweden)

    Lucie Sperková,

    2015-10-01

    Full Text Available The aim of the paper is to design a general method usable for measuring the quality of the service from the customer’s point of view with the help of content analytics. Large amount of unstructured data is created by customers of the service. This data can provide a valuable feedback from the service usage. Customers talk among themselves about their experiences and feelings from consumption of the service. The design of the method is based on a systematic literature review in the area of the service quality and unstructured data analysis. Analytics and quality measurement models are collected and critically evaluated regarding their potential use for measuring IT service quality. The method can be used by IT service provider to measure and monitor service quality based on World-of-Mouth in order to continual service improvement.

  6. A systematic method based on statistical pattern recognition for estimating product quality on-line

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    To avoid the complexity of building mechanistic models by studying the inner nature of the object, a systematic method based on statistical pattern recognition is developed in order to estimate the product quality on-lipe. The mapping relationship between a feature space and a product quality space can be built by using regression analysis, and in applying clustering analysis the product quality space can be partitioned automatically. Eventually, estimating product quality on-line can be accomplished by sorting the mapped data in the partitioned quality space. A concrete problem is proposed which has a relatively small ratio of training data to input variables. By implementing the method mentioned above, a satisfying result has been achieved. Furthermore, the further question about choosing suitable mapping methods is briefly discussed.

  7. The meat product quality control by a polarimetric method

    Science.gov (United States)

    Blokhina, Anastasia A.; Ryzhova, Victoria A.; Korotaev, Valery V.; Kleshchenok, Maksim A.

    2017-05-01

    Analysis of the polarization characteristics of the scattered radiation of biological tissues in some cases provides a qualitatively new results in the study of biological samples. These results can be used in medicine and food industry. As a result of the work, it was determined that the high concentration of scattering particles, the nonuniformity of their dimensions, forms make the task of creating an adequate optical model of a biotissue quite difficult, though many interesting tissue properties can be potentially studied by means of polarized light. In this case, the method for control the freshness of meat samples is considered for by obtaining the Stokes parameters of the polarized radiation scattered forward by the meat product.

  8. Chromatographic Methods to Evaluate Nutritional Quality in Oat.

    Science.gov (United States)

    Montilla-Bascón, Gracia; Broeckling, Corey D; Hoekenga, Owen A; Prats, Elena; Sorrells, Mark; Isidro-Sánchez, Julio

    2017-01-01

    Oats (A. sativa L.) have an important and positive role in human diet and health. The health benefits of oats are attributed to its multifunctional characteristic and nutritional profile, being an important source of soluble dietary fiber, well-balanced proteins, unsaturated fatty acids, vitamins, essential minerals, and a good source of natural antioxidants. These antioxidants include the avenanthramides (Avns) and avenalumic acids, which are unique to oats among cereals. High-performance liquid chromatography allows a simultaneous quantification of free amino acids and biogenic amines in oat samples as their OPA/FMOC-CL (o-phthalaldehyde/9-fluorenylmethoxycarbonyl chloride) derivatives. In addition, an ultra-performance liquid chromatography/mass spectrometry method was developed to quantify and characterize avenanthramides contained in oat samples.

  9. Quality of dry ginger (Zingiber officinale) by different drying methods.

    Science.gov (United States)

    E, Jayashree; R, Visvanathan; T, John Zachariah

    2014-11-01

    Ginger rhizomes sliced to various lengths of 5, 10, 15, 20, 30, 40, 50 mm and whole rhizomes were dried from an initial moisture content of 81.3 % to final moisture content of less than 10 % by various drying methods like sun drying, solar tunnel drying and cabinet tray drying at temperatures of 50, 55, 60 and 65 °C. Slicing of ginger rhizomes significantly reduced the drying time of ginger in all the drying methods. It was observed that drying of whole ginger rhizomes under sun took the maximum time (9 days) followed by solar tunnel drying (8 days). Significant reduction in essential oil and oleoresin content of dry ginger was found as the slice length decreased. The important constituents of ginger essential oil like zingiberene, limonene, linalool, geraniol and nerolidol as determined using a gas chromatography was also found to decrease during slicing and as the drying temperature increased. The pungency constituents in the oleoresin of ginger like total gingerols and total shogoals as determined using a reverse phase high performance liquid chromatography also showed a decreasing trend on slicing and with the increase in drying temperature. It was observed from the drying studies that whole ginger rhizomes dried under sun drying or in a solar tunnel drier retained the maximum essential oil (13.9 mg/g) and oleoresin content (45.2 mg/g) of dry ginger. In mechanical drying, the drying temperature of 60 °C was considered optimum however there was about 12.2 % loss in essential oil at this temperature.

  10. Dependence of Growing High-Quality Gem Diamonds on Growth Rates by Temperature Gradient Method

    Institute of Scientific and Technical Information of China (English)

    ZANG Chuan-Yi; JIA Xiao-Peng; REN Guo-Zhong; WANG Xian-Cheng

    2004-01-01

    @@ Using the temperature gradient method under high pressure and high temperature, we investigate the dependence of growing high-quality gem diamond crystals on the growth rates. It is found that the lower the growth rate of gem diamond crystals, the larger the temperature range of growing high-quality gem diamond crystals, and the easier the control of temperature.

  11. Methods for Examining the Psychometric Quality of Subscores: A Review and Application

    Science.gov (United States)

    Wedman, Jonathan; Lyrén, Per-Erik

    2015-01-01

    When subscores on a test are reported to the test taker, the appropriateness of reporting them depends on whether they provide useful information above what is provided by the total score. Subscores that fail to do so lack adequate psychometric quality and should not be reported. There are several methods for examining the quality of subscores,…

  12. A simple method for boosting the beam quality of commercial DPL

    Institute of Scientific and Technical Information of China (English)

    张光寅; 焦志勇; 颜彩繁; 丁欣; 张潮波; 张晓华; 顾学文; 宋峰

    2003-01-01

    A simple method for boosting the beam quality of a commercial laser diode pumped laser (DPL) is put forward.By keeping one of the mirrors unchanged and the moving the other mirror a proper distance away from the laser rod,high beam quality laser output is realized.

  13. Application Biosphere Compatibility Concept To Evaluate The Quality Of Urban Environment By Bioindication Methods

    Science.gov (United States)

    Vorobyov, S.

    2017-01-01

    This article focuses on the application of methods biondisation different types of urban green areas to assess the quality of urban environment from the standpoint of compatibility biosphere concept. To assess urban environmental quality, we used a variety of areas of the city of Orel with different levels of human impact.

  14. Extension Multi-factorial Evaluation Method on Water Quality Early-warning

    Institute of Scientific and Technical Information of China (English)

    Rong; GUO; Yong; ZHANG; Fangjian; XIE; Sheng; ZHONG

    2013-01-01

    Extension multi-factorial evaluation method was used in water quality early-earning in Yincungang River based on MATLAB. The results showed that water quality in summer was safe,while that in other three seasons were in pre-warning state with the order of winter > spring > autumn.

  15. A simple method for the quality control of [F-18]FDG

    DEFF Research Database (Denmark)

    Koziorowski, J.

    2010-01-01

    Most automated synthesis modules produce [F-18]FDG within half an hour, but the quality control involving up to three separate methods and three different analytical systems is time consuming. The use of HPLC, TLC, and GC for the quality control of [F-18]FDG is both time consuming and expensive...

  16. A simple method for the quality control of [(18)F]FDG

    DEFF Research Database (Denmark)

    Koziorowski, J

    2010-01-01

    Most automated synthesis modules produce [(18)F]FDG within half an hour, but the quality control involving up to three separate methods and three different analytical systems is time consuming. The use of HPLC, TLC, and GC for the quality control of [(18)F]FDG is both time consuming and expensive...

  17. A Cognitive Modeling Method of the Life Quality Indicators in Terms of External Factors

    Directory of Open Access Journals (Sweden)

    L. V. Massel

    2016-01-01

    Full Text Available The article discusses a potential use of the methods of cognitive modeling in the field of quality of life. The quality of life, as a universal indicator of human self-perception to feel his sense of satisfaction from various parts of his life, is difficult to assess by strictly mathematical methods, so the authors suggest using the cognitive modeling. The quality of life in his estimation for the convenience of research activity is divided into components - indicators of the quality of life. The widespread indicator "quality of life" and the complexity of the development of its assessment methods lead to high relevance of the authors-proposed method.The introduction provides an overview of current approaches to assessing the quality of life. Among all these approaches the most advantageous is an objectively subjective one. The paper gives a brief assessment of cognitive modeling methods, which are, essentially, a way of graphic and structural elements of reflection and relationships in complex systems. As a result of the analysis of existing research in this area, was found the potential for creating cognitive models of the quality of life and its indicators and was defined the place of the proposed method, among others. The paper presents the method itself, as a series of steps, and focuses on the promising opportunities for researchers of the quality of life from its using.Among the possible lines to use cognitive modeling of the life quality indicators can be three main ones: implementation of new methods to assess the quality of life; choice of the most appropriate technique for a particular study among available methods; realization of the cognitive model and numerical experiment, which allows seeing the effect of external factors on the individual indicators of the quality of life. Thus, due to the high relevance and significant benefits from the use of the proposed method, the article is of interest to researchers of the quality of life

  18. Effects of peeling methods on the quality of cubiu fruits

    Directory of Open Access Journals (Sweden)

    Luty Gomez Caceres

    2012-06-01

    Full Text Available Cubiu (Solanum sessiliflorum Dunal is an Amazonian Basin native fruit. Its importance comes from its high contents of pectin. Currently, processing technologies are necessary for the substitution of the traditional system (small crops and small-scale processing for a larger scale system and thus increase the use of biodiversity and promote the implementation of Local Productive Arrangements of agribusiness in the Amazon. This research aims to evaluate the methods of peeling cubiu. Ripe fruits were divided into lots (150 each and subjected to the following treatments: immersion in 2.5% NaOH boiling solution for 5 minutes, exposure to water vapor, and immersion in water at 96 ºC for 5, 10, 15 and 20 minutes. The peel released during heat treatment and immediately removed under running tap water. In the control treatment, the fruits were manually peeled (unheated with a stainless steel knife. The treatments were evaluated for completeness and ease of peeling, tissue integrity, texture, and peroxidase activity. The immersion in 2.5% NaOH boiling solution (5 minutes stood out as the best treatment since it inhibited the enzymatic browning and intensified the natural yellow color of the cubiu fruit and easily and fully peeled the whole fruit more rapidly without damaging its tissues. This treatment was chosen as the most advantageous because it can promote simultaneous peeling and bleaching. Therefore, it is recommended for cubiu industrial processing.

  19. A Simplified but Effective Method for the Quality Control of Medicinal ...

    African Journals Online (AJOL)

    A Simplified but Effective Method for the Quality Control of Medicinal Plants by Planar ... peoples, the safety and effectivity is frequently not such a big concern. With more people collecting and distributing herbal medicine, the offered product is ...

  20. Saasquality - A Method for Quality Evaluation of Software as a Service (Saas

    Directory of Open Access Journals (Sweden)

    Nemesio Freitas Duarte Filho

    2013-07-01

    Full Text Available The market for software products offered as a service (SaaS is growing steadily and has attractedsuppliers from different segments of the global IT market. However, the use of the SaaS products brings arange of challenges,both in the organizational, cultural and technological areas. A difficulty that existstoday is the lack of methods and models for assessing the quality of these products. This document presentsa method to assess the quality of a software product offeredas a service, named SaaSQuality. Theproposed method has a quality model appropriate to the SaaS context, based on standards and models ofsoftware quality (ISO 9126 and models for IT management (ITIL and COBIT. The experimental resultsobtained througha case study show that the method offers suitable assessment practices for Software as aService.

  1. Sensory and rapid instrumental methods as a combined tool for quality control of cooked ham

    Directory of Open Access Journals (Sweden)

    Sara Barbieri

    2016-11-01

    This study can be considered a first application of this combined approach that could represent a suitable and fast method to verify if the meat product purchased by consumer match its description in terms of compliance with the claimed quality.

  2. Comparison of methods for high quantity and quality genomic DNA extraction from raw cow milk.

    Science.gov (United States)

    Usman, T; Yu, Y; Liu, C; Fan, Z; Wang, Y

    2014-04-29

    Isolation of sufficient quantities of high quality DNA is a prerequisite for molecular studies. Milk somatic cells can be used; however, inhibitors such as fats and proteins make milk a difficult medium for extracting large amounts of quality DNA. We optimized, evaluated and compared three methods, Modified Nucleospin Blood Kit method, Modified TianGen Kit method and Phenol-Chloroform method for genomic DNA extraction from bovine milk. Individual cows' milk and bulk milk samples were collected from a China agricultural university dairy farm. Genomic DNA extracted from each milk sample by the three methods was evaluated for quantity and purity by spectrophotometry and gel electrophoresis, as well as PCR and sequencing. All the three methods were found suitable for genomic DNA isolation from bovine milk, PCR applications, and sequencing. Comparing the three methods, we found that the Modified Nucleospin Blood Kit method was significantly better than the Phenol-Chloroform method in terms of quantity as well as quality (amount, concentration, 260/280 nm and 260/230 nm absorbance ratio), whereas, the Modified TianGen Kit method was more efficient than the Phenol-Chloroform method and cheaper than the Modified Nucleospine Blood Kit method; it yielded reasonably good quantities of good quality DNA and would be suitable for large-scale genotyping of lactating cows.

  3. Towards Unification of Methods for Speech, Audio, Picture and Multimedia Quality Assessment

    DEFF Research Database (Denmark)

    Zielinski, S.; Rumsey, F.; Bech, Søren

    2015-01-01

    The paper addresses the need to develop unified methods for subjective and objective quality assessment across speech, audio, picture, and multimedia applications. Commonalities and differences between the currently used standards are overviewed. Examples of the already undertaken research...... attempting to “bridge the gap” between the quality assessment methods used in various disciplines are indicated. Prospective challenges faced by researchers in the unification process are outlined. They include development of unified scales, defining unified anchors, integration of objective models...

  4. Digital Watermarking Method Warranting the Lower Limit of Image Quality of Watermarked Images

    Directory of Open Access Journals (Sweden)

    Iwata Motoi

    2010-01-01

    Full Text Available We propose a digital watermarking method warranting the lower limit of the image quality of watermarked images. The proposed method controls the degradation of a watermarked image by using a lower limit image. The lower limit image means the image of the worst quality that users can permit. The proposed method accepts any lower limit image and does not require it at extraction. Therefore lower limit images can be decided flexibly. In this paper, we introduce 2-dimensional human visual MTF model as an example of obtaining lower limit images. Also we use JPEG-compressed images of quality 75% and 50% as lower limit images. We investigate the performance of the proposed method by experiments. Moreover we compare the proposed method using three types of lower limit images with the existing method in view of the tradeoff between PSNR and the robustness against JPEG compression.

  5. Novel method for the evaluation of data quality based on fuzzy control

    Institute of Scientific and Technical Information of China (English)

    Ban Xiaojuan; Ning Shurong; Xu Zhaolin; Cheng Peng

    2008-01-01

    One of the goals of data collection is preparing for decision-making, so high quality requirement must be satisfied. Rational evaluation of data quality is an effective way to identify data problem in time, and the quality of data after this evaluation is satisfactory with the requirement of decision maker. A fuzzy neural network based research method of data quality evaluation is proposed. First, the criteria for the evaluation of data quality are selected to construct the fuzzy sets of evaluating grades, and then by using the learning ability of NN, the objective evaluation of membership is carried out, which can be used for the effective evaluation of data quality. This research has been used in the platform of data report of national compulsory education outlay guarantee' from the Chinese Ministry of Education. This method can be used for the effective evaluation of data quality worldwide, and the data quality situation can be found out more completely, objectively, and in better time by using the method.

  6. MUSQA: a CS method to build a multi-standard quality management system

    Science.gov (United States)

    Cros, Elizabeth; Sneed, Isabelle

    2002-07-01

    CS Communication & Systèmes, through its long quality management experience, has been able to build and evolve its Quality Management System according to clients requirements, norms, standards and models (ISO, DO178, ECSS, CMM, ...), evolving norms (transition from ISO 9001:1994 to ISO 9001:2000) and the TQM approach, being currently deployed. The aim of this paper is to show how, from this enriching and instructive experience, CS has defined and formalised its method: MuSQA (Multi-Standard Quality Approach). This method allows to built a new Quality Management System or simplify and unify an existing one. MuSQA objective is to provide any organisation with an open Quality Management System, which is able to evolve easily and turns to be a useful instrument for everyone, operational as well as non-operational staff.

  7. Evaluating Service Quality from Patients' Perceptions: Application of Importance-performance Analysis Method.

    Science.gov (United States)

    Mohebifar, Rafat; Hasani, Hana; Barikani, Ameneh; Rafiei, Sima

    2016-08-01

    Providing high service quality is one of the main functions of health systems. Measuring service quality is the basic prerequisite for improving quality. The aim of this study was to evaluate the quality of service in teaching hospitals using importance-performance analysis matrix. A descriptive-analytic study was conducted through a cross-sectional method in six academic hospitals of Qazvin, Iran, in 2012. A total of 360 patients contributed to the study. The sampling technique was stratified random sampling. Required data were collected based on a standard questionnaire (SERVQUAL). Data analysis was done through SPSS version 18 statistical software and importance-performance analysis matrix. The results showed a significant gap between importance and performance in all five dimensions of service quality (p quality gap and "responsiveness" had the lowest gap (1.97). Also, according to findings, reliability and assurance were in Quadrant (I), empathy was in Quadrant (II), and tangibles and responsiveness were in Quadrant (IV) of the importance-performance matrix. The negative gap in all dimensions of quality shows that quality improvement is necessary in all dimensions. Using quality and diagnosis measurement instruments such as importance-performance analysis will help hospital managers with planning of service quality improvement and achieving long-term goals.

  8. Towards a Quality Assessment Method for Learning Preference Profiles in Negotiation

    Science.gov (United States)

    Hindriks, Koen V.; Tykhonov, Dmytro

    In automated negotiation, information gained about an opponent's preference profile by means of learning techniques may significantly improve an agent's negotiation performance. It therefore is useful to gain a better understanding of how various negotiation factors influence the quality of learning. The quality of learning techniques in negotiation are typically assessed indirectly by means of comparing the utility levels of agreed outcomes and other more global negotiation parameters. An evaluation of learning based on such general criteria, however, does not provide any insight into the influence of various aspects of negotiation on the quality of the learned model itself. The quality may depend on such aspects as the domain of negotiation, the structure of the preference profiles, the negotiation strategies used by the parties, and others. To gain a better understanding of the performance of proposed learning techniques in the context of negotiation and to be able to assess the potential to improve the performance of such techniques a more systematic assessment method is needed. In this paper we propose such a systematic method to analyse the quality of the information gained about opponent preferences by learning in single-instance negotiations. The method includes measures to assess the quality of a learned preference profile and proposes an experimental setup to analyse the influence of various negotiation aspects on the quality of learning. We apply the method to a Bayesian learning approach for learning an opponent's preference profile and discuss our findings.

  9. Using an innovative combination of quality-by-design and green analytical chemistry approaches for the development of a stability indicating UHPLC method in pharmaceutical products.

    Science.gov (United States)

    Boussès, Christine; Ferey, Ludivine; Vedrines, Elodie; Gaudin, Karen

    2015-11-10

    An innovative combination of green chemistry and quality by design (QbD) approach is presented through the development of an UHPLC method for the analysis of the main degradation products of dextromethorphan hydrobromide. QbD strategy was integrated to the field of green analytical chemistry to improve method understanding while assuring quality and minimizing environmental impacts, and analyst exposure. This analytical method was thoroughly evaluated by applying risk assessment and multivariate analysis tools. After a scouting phase aimed at selecting a suitable stationary phase and an organic solvent in accordance with green chemistry principles, quality risk assessment tools were applied to determine the critical process parameters (CPPs). The effects of the CPPs on critical quality attributes (CQAs), i.e., resolutions, efficiencies, and solvent consumption were further evaluated by means of a screening design. A response surface methodology was then carried out to model CQAs as function of the selected CPPs and the optimal separation conditions were determined through a desirability analysis. Resulting contour plots enabled to establish the design space (DS) (method operable design region) where all CQAs fulfilled the requirements. An experimental validation of the DS proved that quality within the DS was guaranteed; therefore no more robustness study was required before the validation. Finally, this UHPLC method was validated using the concept of total error and was used to analyze a pharmaceutical drug product. Copyright © 2015 Elsevier B.V. All rights reserved.

  10. Implementation of Six Sigma Method to Maintain The Quality of Construction Projects

    Directory of Open Access Journals (Sweden)

    Yusuf Latief

    2010-10-01

    Full Text Available Six sigma (6-sigma is a method that widely developed in the world, especially in manufacturing industry to decrease failures in achieving good quality in construction projects. The objective of this research is to explore the existing condition of quality management and the aplication of 6-sigma method in maintaining quality of construction projects. Structured interviews to experienced experts and people who were recommended by their companies were conducted. Non-parametric analysis using frequencies distribution procedures were used for analysis. The result shows that existing condition in quality management of construction project in Indonesia have been implemented 6-sigma method approach, that concern with is how to adapt with either from internal or external condition of that project.

  11. Evaluation of air quality zone classification methods based on ambient air concentration exposure.

    Science.gov (United States)

    Freeman, Brian; McBean, Ed; Gharabaghi, Bahram; Thé, Jesse

    2017-05-01

    Air quality zones are used by regulatory authorities to implement ambient air standards in order to protect human health. Air quality measurements at discrete air monitoring stations are critical tools to determine whether an air quality zone complies with local air quality standards or is noncompliant. This study presents a novel approach for evaluation of air quality zone classification methods by breaking the concentration distribution of a pollutant measured at an air monitoring station into compliance and exceedance probability density functions (PDFs) and then using Monte Carlo analysis with the Central Limit Theorem to estimate long-term exposure. The purpose of this paper is to compare the risk associated with selecting one ambient air classification approach over another by testing the possible exposure an individual living within a zone may face. The chronic daily intake (CDI) is utilized to compare different pollutant exposures over the classification duration of 3 years between two classification methods. Historical data collected from air monitoring stations in Kuwait are used to build representative models of 1-hr NO2 and 8-hr O3 within a zone that meets the compliance requirements of each method. The first method, the "3 Strike" method, is a conservative approach based on a winner-take-all approach common with most compliance classification methods, while the second, the 99% Rule method, allows for more robust analyses and incorporates long-term trends. A Monte Carlo analysis is used to model the CDI for each pollutant and each method with the zone at a single station and with multiple stations. The model assumes that the zone is already in compliance with air quality standards over the 3 years under the different classification methodologies. The model shows that while the CDI of the two methods differs by 2.7% over the exposure period for the single station case, the large number of samples taken over the duration period impacts the sensitivity of

  12. Quality of life among dermatology patients: a systematic review of investigations using qualitative methods.

    Science.gov (United States)

    Singh, Sanminder; Ehsani-Chimeh, Nazanin; Kornmehl, Heather; Armstrong, April W

    2017-07-13

    Quality of life may be assessed using quantitative or qualitative methods. Quantitative methods are commonly used in research settings; however, they may fail to capture the full range of patient experiences and impact on quality of life. Qualitative methods may be used to address this limitation. In this systematic review, we aim to synthesize data from articles utilizing qualitative methods to assess quality of life in dermatology patients. We performed a systematic review search using the MEDLINE, EMBASE, and SCOPUS databases. The search was conducted using the following search criteria: ("Dermatology" [MeSH]) AND ("Quality of Life" [MeSH]), AND ("Qualitative Research" [MeSH]), searching literature spanning from January 1, 1946- October 5, 2016. The systematic review of 15 articles included 533 dermatology patients. Patients expressed frustration over the unpredictability of disease symptoms and having to compensate for the subsequent limitations by altering their daily routines. Patients also reported profound helplessness due to chronic skin disease and social isolation in an effort to hide their disease. Patients noted the patient-provider relationship as a source of support and information exchange, with the goal to form easy to use treatment plans that met both physician and patient expectations. Qualitative assessment of patient quality of life can provide new insights into the patient experience and the impact of their skin disease. Qualitative methodology may capture meaningful information that may be overlooked by quantitative methods, and it should be included in quality of life research.

  13. A novel method based solely on FPGA units enabling measurement of time and charge of analog signals in Positron Emission Tomography

    CERN Document Server

    Pałka, M; Białas, P; Czerwiński, E; Kapłon, Ł; Kochanowski, A; Korcyl, G; Kowal, J; Kowalski, P; Kozik, T; Krzemień, W; Molenda, M; Moskal, P; Niedźwiecki, Sz; Pawlik, M; Raczyński, L; Rudy, Z; Salabura, P; Sharma, N G; Silarski, M; Słomski, A; Smyrski, J; Strzelecki, A; Wiślicki, W; Zieliński, M; Zoń, N

    2013-01-01

    This article presents a novel technique for precise measurement of time and charge based solely on FPGA (Field Programmable Gate Array) device and few satellite discrete electronic components used in Positron Emission Tomography (PET). Described approach simplifies electronic circuits, reduces the power consumption, lowers costs, merges front-end electronics with digital electronics and also makes more compact final design. Furthermore, it allows to measure time when analog signals cross a reference voltage at different threshold levels with a very high precision of $\\sim$ 10ps (rms) and thus enables sampling of signals in a voltage domain.

  14. Growth and Photovoltaic Properties of High-Quality GaAs Nanowires Prepared by the Two-Source CVD Method.

    Science.gov (United States)

    Wang, Ying; Yang, Zaixing; Wu, Xiaofeng; Han, Ning; Liu, Hanyu; Wang, Shuobo; Li, Jun; Tse, WaiMan; Yip, SenPo; Chen, Yunfa; Ho, Johnny C

    2016-12-01

    Growing high-quality and low-cost GaAs nanowires (NWs) as well as fabricating high-performance NW solar cells by facile means is an important development towards the cost-effective next-generation photovoltaics. In this work, highly crystalline, dense, and long GaAs NWs are successfully synthesized using a two-source method on non-crystalline SiO2 substrates by a simple solid-source chemical vapor deposition method. The high V/III ratio and precursor concentration enabled by this two-source configuration can significantly benefit the NW growth and suppress the crystal defect formation as compared with the conventional one-source system. Since less NW crystal defects would contribute fewer electrons being trapped by the surface oxides, the p-type conductivity is then greatly enhanced as revealed by the electrical characterization of fabricated NW devices. Furthermore, the individual single NW and high-density NW parallel arrays achieved by contact printing can be effectively fabricated into Schottky barrier solar cells simply by employing asymmetric Ni-Al contacts, along with an open circuit voltage of ~0.3 V. All these results indicate the technological promise of these high-quality two-source grown GaAs NWs, especially for the realization of facile Schottky solar cells utilizing the asymmetric Ni-Al contact.

  15. Growth and Photovoltaic Properties of High-Quality GaAs Nanowires Prepared by the Two-Source CVD Method

    Science.gov (United States)

    Wang, Ying; Yang, Zaixing; Wu, Xiaofeng; Han, Ning; Liu, Hanyu; Wang, Shuobo; Li, Jun; Tse, WaiMan; Yip, SenPo; Chen, Yunfa; Ho, Johnny C.

    2016-04-01

    Growing high-quality and low-cost GaAs nanowires (NWs) as well as fabricating high-performance NW solar cells by facile means is an important development towards the cost-effective next-generation photovoltaics. In this work, highly crystalline, dense, and long GaAs NWs are successfully synthesized using a two-source method on non-crystalline SiO2 substrates by a simple solid-source chemical vapor deposition method. The high V/III ratio and precursor concentration enabled by this two-source configuration can significantly benefit the NW growth and suppress the crystal defect formation as compared with the conventional one-source system. Since less NW crystal defects would contribute fewer electrons being trapped by the surface oxides, the p-type conductivity is then greatly enhanced as revealed by the electrical characterization of fabricated NW devices. Furthermore, the individual single NW and high-density NW parallel arrays achieved by contact printing can be effectively fabricated into Schottky barrier solar cells simply by employing asymmetric Ni-Al contacts, along with an open circuit voltage of ~0.3 V. All these results indicate the technological promise of these high-quality two-source grown GaAs NWs, especially for the realization of facile Schottky solar cells utilizing the asymmetric Ni-Al contact.

  16. Organising to Enable Innovation

    DEFF Research Database (Denmark)

    Brink, Tove

    2016-01-01

    The purpose of this conceptual paper is to reveal how organising can enable innovation across organisational layers and organisational units. This approach calls for a cross-disciplinary literature review. The aim is to provide an integrated understanding of innovation in an organisational approa...... of explorative and exploitative learning in uncertain environments. Shedding light on the cross-disciplinary theories to organise innovation provides a contribution at the firm level to enable innovation.......The purpose of this conceptual paper is to reveal how organising can enable innovation across organisational layers and organisational units. This approach calls for a cross-disciplinary literature review. The aim is to provide an integrated understanding of innovation in an organisational approach....... The findings reveal a continous organising process between individual/ team creativity and organisational structures/control to enable innovation at firm level. Organising provides a dynamic approach and contains the integrated reconstruction of creativity, structures and boundaries for enhanced balance...

  17. Problem-solving and developing quality management methods and techniques on the example of automotive industry

    Directory of Open Access Journals (Sweden)

    Jacek Łuczak

    2015-12-01

    Full Text Available The knowledge about methods and techniques of quality management together with their effective use can be definitely regarded as an indication of high organisational culture. Using such methods and techniques in an effective way can be attributed to certain level of maturity, as far as the quality management system in an organisation is concerned. There is in the paper an analysis of problem-solving methods and techniques of quality management in the automotive sector in Poland. The survey was given to the general population, which in case of the study consisted of companies operating in Poland that had certified quality management systems against ISO/TS 16949. The results of the conducted survey and the conclusions of the author can show actual and potential OEM suppliers (both 1st and 2nd tier in which direction their strategies for development and improvement of quality management systems should go in order to be effective. When the universal character of methods and techniques used in the surveyed population of companies is taken into consideration, it can be assumed that the results of the survey are also universal for all organisations realising the TQM strategy. The results of the research confirmed that methods which are also the basis for creating key system documents are the most relevant ones, i.e. flowcharts and FMEA, and moreover process monitoring tools (SPC and problem solving methods -above all 8D.

  18. Using and reporting the Delphi method for selecting healthcare quality indicators: a systematic review.

    Directory of Open Access Journals (Sweden)

    Rym Boulkedid

    Full Text Available OBJECTIVE: Delphi technique is a structured process commonly used to developed healthcare quality indicators, but there is a little recommendation for researchers who wish to use it. This study aimed 1 to describe reporting of the Delphi method to develop quality indicators, 2 to discuss specific methodological skills for quality indicators selection 3 to give guidance about this practice. METHODOLOGY AND MAIN FINDING: Three electronic data bases were searched over a 30 years period (1978-2009. All articles that used the Delphi method to select quality indicators were identified. A standardized data extraction form was developed. Four domains (questionnaire preparation, expert panel, progress of the survey and Delphi results were assessed. Of 80 included studies, quality of reporting varied significantly between items (9% for year's number of experience of the experts to 98% for the type of Delphi used. Reporting of methodological aspects needed to evaluate the reliability of the survey was insufficient: only 39% (31/80 of studies reported response rates for all rounds, 60% (48/80 that feedback was given between rounds, 77% (62/80 the method used to achieve consensus and 57% (48/80 listed quality indicators selected at the end of the survey. A modified Delphi procedure was used in 49/78 (63% with a physical meeting of the panel members, usually between Delphi rounds. Median number of panel members was 17(Q1:11; Q3:31. In 40/70 (57% studies, the panel included multiple stakeholders, who were healthcare professionals in 95% (38/40 of cases. Among 75 studies describing criteria to select quality indicators, 28 (37% used validity and 17(23% feasibility. CONCLUSION: The use and reporting of the Delphi method for quality indicators selection need to be improved. We provide some guidance to the investigators to improve the using and reporting of the method in future surveys.

  19. 30 CFR 28.33 - Quality control test methods, equipment, and records; review by MSHA; revocation of approval.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Quality control test methods, equipment, and... Quality Control § 28.33 Quality control test methods, equipment, and records; review by MSHA; revocation... control test methods, equipment, and records, and to interview any employee or agent of the applicant in...

  20. Study on the Application of 6σ Method in Shoemaking Enterprise Quality Improvement

    Directory of Open Access Journals (Sweden)

    Wang Ting

    2017-01-01

    Full Text Available With the development of science as well as technology and the influx of shoemaking companies abroad, our traditional shoemaking enterprises face greater pressure to survive, and product quality problems are in urgent need of improvement. Aiming at the quality problems of M shoemaking enterprise, DMAIC method is used to conduct the product quality improvement, and a mathematical statistics software Minitab is used to analyze the data. Moreover, the optimum combination of the key influencing factors is determined by orthogonal experiment design as well as a set of specific quality improvement plans are put forward. Finally, the production process capability of M enterprise is improved, the product bonding strength is enhanced, customer satisfaction is improved, and the thoughts of product quality improvement and reference are provided for domestic traditional shoemaking enterprises.

  1. Methods for collecting benthic invertebrate samples as part of the National Water-Quality Assessment Program

    Science.gov (United States)

    Cuffney, Thomas F.; Gurtz, Martin E.; Meador, Michael R.

    1993-01-01

    Benthic invertebrate communities are evaluated as part of the ecological survey component of the U.S. Geological Survey's National Water-Quality Assessment Program. These biological data are collected along with physical and chemical data to assess water-quality conditions and to develop an understanding of the factors that affect water-quality conditions locally, regionally, and nationally. The objectives of benthic invertebrate community characterizations are to (1) develop for each site a list of tax a within the associated stream reach and (2) determine the structure of benthic invertebrate communities within selected habitats of that reach. A nationally consistent approach is used to achieve these objectives. This approach provides guidance on site, reach, and habitat selection and methods and equipment for qualitative multihabitat sampling and semi-quantitative single habitat sampling. Appropriate quality-assurance and quality-control guidelines are used to maximize the ability to analyze data within and among study units.

  2. [Review of data quality dimensions and applied methods in the evaluation of health information systems].

    Science.gov (United States)

    Lima, Claudia Risso de Araujo; Schramm, Joyce Mendes de Andrade; Coeli, Claudia Medina; da Silva, Márcia Elizabeth Marinho

    2009-10-01

    In Brazil, quality monitoring of data from the various health information systems does not follow a regular evaluation plan. This paper reviews quality evaluation initiatives related to the Brazilian information systems, identifying the selected quality dimensions and the method employed. The SciELO and LILACS databases were searched, as were the bibliographical references from articles identified in the search. 375 articles were initially identified, leaving a final total of 78 after exclusions. The four most frequent dimensions in articles totaled approximately 90% of the analyses. The studies prioritized certain quality dimensions: reliability, validity, coverage, and completeness. Half of the studies were limited to data from Rio de Janeiro and São Paulo. The limited number of studies on some systems and their unequal distribution between regions of the country hinder a comprehensive quality assessment of Brazil's health information systems. The importance of accurate information highlights the need to implement a data management policy for health information systems in Brazil.

  3. Comparing Methods for Extracting Heavy Metals from Histosols for Establishing Quality Reference Values

    Directory of Open Access Journals (Sweden)

    Erica Souto Abreu Lima

    Full Text Available ABSTRACT The diversity of methods for heavy metal extraction from soils complicates comparison of results used by environmental agencies to establish quality reference values. The aim of this study was to evaluate three soil digestion methods regarding the solubilizing capacity of Ba, Cr, Cu, Fe, Mn, Ni, Pb and Zn, and to propose a standard method to establish Quality Reference Values (QRVs for Brazilian Histosols. Twenty soil samples were selected to evaluate the USEPA 3051, USEPA 3051A and Aqua Regia methods in a closed system. The methods tested were statistically similar regarding Cu, Fe and Mn extraction from soils. However, the methods can not be considered similar for Ba, Cr, Ni, Pb and Zn; Aqua Regia recorded the highest levels, except for Ba. The Aqua Regia method proved suitable for metal extraction from soils with organic characteristics and can be used to establish QRVs.

  4. Image quality assessment method based on nonlinear feature extraction in kernel space

    Institute of Scientific and Technical Information of China (English)

    Yong DING‡; Nan LI; Yang ZHAO; Kai HUANG

    2016-01-01

    To match human perception, extracting perceptual features effectively plays an important role in image quality assessment. In contrast to most existing methods that use linear transformations or models to represent images, we employ a complex mathematical expression of high dimensionality to reveal the statistical characteristics of the images. Furthermore, by introducing kernel methods to transform the linear problem into a nonlinear one, a full-reference image quality assessment method is proposed based on high-dimensional nonlinear feature extraction. Experiments on the LIVE, TID2008, and CSIQ databases demonstrate that nonlinear features offer competitive performance for image inherent quality representation and the proposed method achieves a promising performance that is consistent with human subjective evaluation.

  5. Effects of different drying methods on the product quality and volatile compounds of whole shiitake mushrooms.

    Science.gov (United States)

    Tian, Yuting; Zhao, Yingting; Huang, Jijun; Zeng, Hongliang; Zheng, Baodong

    2016-04-15

    Various drying methods play important roles in the preservation of foods. However, how the different drying methods affect the quality of some foods is not clear. This paper evaluates the effects of hot air, vacuum, microwave, and microwave vacuum drying techniques on important qualities and volatile compounds of whole shiitake (Lentinus edodes) mushrooms. These four drying methods resulted in a significantly (pdried products. Microwave vacuum drying helped to maintain larger amounts of taste-active amino acids, and improved nutrient retention and color attributes. Furthermore, the uniform honeycomb network created by microwave vacuum drying along with a less collapsed structure of dried samples can be used to explain the observed high rehydration ratio. Therefore, microwave vacuum drying should be a potential method for obtaining high-quality dried mushrooms.

  6. A high throughput DNA extraction method with high yield and quality

    Directory of Open Access Journals (Sweden)

    Xin Zhanguo

    2012-07-01

    Full Text Available Abstract Background Preparation of large quantity and high quality genomic DNA from a large number of plant samples is a major bottleneck for most genetic and genomic analyses, such as, genetic mapping, TILLING (Targeting Induced Local Lesion IN Genome, and next-generation sequencing directly from sheared genomic DNA. A variety of DNA preparation methods and commercial kits are available. However, they are either low throughput, low yield, or costly. Here, we describe a method for high throughput genomic DNA isolation from sorghum [Sorghum bicolor (L. Moench] leaves and dry seeds with high yield, high quality, and affordable cost. Results We developed a high throughput DNA isolation method by combining a high yield CTAB extraction method with an improved cleanup procedure based on MagAttract kit. The method yielded large quantity and high quality DNA from both lyophilized sorghum leaves and dry seeds. The DNA yield was improved by nearly 30 fold with 4 times less consumption of MagAttract beads. The method can also be used in other plant species, including cotton leaves and pine needles. Conclusion A high throughput system for DNA extraction from sorghum leaves and seeds was developed and validated. The main advantages of the method are low cost, high yield, high quality, and high throughput. One person can process two 96-well plates in a working day at a cost of $0.10 per sample of magnetic beads plus other consumables that other methods will also need.

  7. Evaluating website quality: Five studies on user-focused evaluation methods

    NARCIS (Netherlands)

    Elling, S.K.

    2012-01-01

    The benefits of evaluating websites among potential users are widely acknowledged. There are several methods that can be used to evaluate the websites’ quality from a users’ perspective. In current practice, many evaluations are executed with inadequate methods that lack research-based validation. T

  8. Contextual and Analytic Qualities of Research Methods Exemplified in Research on Teaching

    Science.gov (United States)

    Svensson, Lennart; Doumas, Kyriaki

    2013-01-01

    The aim of the present article is to discuss contextual and analytic qualities of research methods. The arguments are specified in relation to research on teaching. A specific investigation is used as an example to illustrate the general methodological approach. It is argued that research methods should be carefully grounded in an understanding of…

  9. Practical Recommendations to Improve the Quality of Training and Methodical Support of Professional Teacher Education

    Science.gov (United States)

    Grebennikov, Valery V.; Grudtsina, Ludmila Yu.; Marchuk, Nikolay N.; Sangadgiev, Badma V.; Kudyashev, Nail K.

    2016-01-01

    The research urgency is caused by the transition to the knowledge society and new demands for training and methodical provision of professional pedagogical education. The purpose of this paper is to develop practical recommendations to improve the quality of training and methodical support of professional pedagogical education. The leading…

  10. Improved method for fibre content and quality analysis and their application to flax genetic diversity investigations

    NARCIS (Netherlands)

    Oever, van den M.J.A.; Bas, N.; Soest, van L.J.M.; Melis, C.; Dam, van J.E.G.

    2003-01-01

    Evaluation for fibre content and quality in a breeding selection program is time consuming and costly. Therefore, this study aims to develop a method for fast and reproducible fibre content analysis on small flax straw samples. A protocol has been developed and verified with fibre screening methods

  11. IMPROVING THE QUALITY OF NEAR-INFRARED IMAGING OF IN VIVOBLOOD VESSELS USING IMAGE FUSION METHODS

    DEFF Research Database (Denmark)

    Jensen, Andreas Kryger; Savarimuthu, Thiusius Rajeeth; Sørensen, Anders Stengaard

    2009-01-01

    We investigate methods for improving the visual quality of in vivo images of blood vessels in the human forearm. Using a near-infrared light source and a dual CCD chip camera system capable of capturing images at visual and nearinfrared spectra, we evaluate three fusion methods in terms of their ...

  12. Contextual and Analytic Qualities of Research Methods Exemplified in Research on Teaching

    Science.gov (United States)

    Svensson, Lennart; Doumas, Kyriaki

    2013-01-01

    The aim of the present article is to discuss contextual and analytic qualities of research methods. The arguments are specified in relation to research on teaching. A specific investigation is used as an example to illustrate the general methodological approach. It is argued that research methods should be carefully grounded in an understanding of…

  13. Improved method for fibre content and quality analysis and their application to flax genetic diversity investigations

    NARCIS (Netherlands)

    Oever, van den M.J.A.; Bas, N.; Soest, van L.J.M.; Melis, C.; Dam, van J.E.G.

    2003-01-01

    Evaluation for fibre content and quality in a breeding selection program is time consuming and costly. Therefore, this study aims to develop a method for fast and reproducible fibre content analysis on small flax straw samples. A protocol has been developed and verified with fibre screening methods

  14. Introduction to Field Water-Quality Methods for the Collection of Metals - 2007 Project Summary

    Science.gov (United States)

    Allen, Monica L.

    2008-01-01

    The U.S. Geological Survey (USGS), Region VI of the U.S. Environmental Protection Agency (USEPA), and the Osage Nation presented three 3-day workshops, in June-August 2007, entitled ?Introduction to Field Water-Quality Methods for the Collection of Metals.? The purpose of the workshops was to provide instruction to tribes within USEPA Region VI on various USGS surface-water measurement methods and water-quality sampling protocols for the collection of surface-water samples for metals analysis. Workshop attendees included members from over 22 tribes and pueblos. USGS instructors came from Oklahoma, New Mexico, and Georgia. Workshops were held in eastern and south-central Oklahoma and New Mexico and covered many topics including presampling preparation, water-quality monitors, and sampling for metals in surface water. Attendees spent one full classroom day learning the field methods used by the USGS Water Resources Discipline and learning about the complexity of obtaining valid water-quality and quality-assurance data. Lectures included (1) a description of metal contamination sources in surface water; (2) introduction on how to select field sites, equipment, and laboratories for sample analysis; (3) collection of sediment in surface water; and (4) utilization of proper protocol and methodology for sampling metals in surface water. Attendees also were provided USGS sampling equipment for use during the field portion of the class so they had actual ?hands-on? experience to take back to their own organizations. The final 2 days of the workshop consisted of field demonstrations of current USGS water-quality sample-collection methods. The hands-on training ensured that attendees were exposed to and experienced proper sampling procedures. Attendees learned integrated-flow techniques during sample collection, field-property documentation, and discharge measurements and calculations. They also used enclosed chambers for sample processing and collected quality

  15. A METHOD OF IMAGE QUALITY ASSESSMENT FOR COMPRESSIVE SAMPLING VIDEO TRANSMISSION

    Institute of Scientific and Technical Information of China (English)

    Chen Shouning; Zheng Baoyu; Li Jing

    2012-01-01

    Based on compressive sampling transmission model,we demonstrate here a method of quality evaluation for the reconstruction images,which is promising for the transmission of unstructured signal with reduced dimension.By this method,the auxiliary information of the recovery image quality is obtained as a feedback to control number of measurements from compressive sampling video stream.Therefore,the number of measurements can be easily derived at the condition of the absence of information sparsity,and the recovery image quality is effectively improved.Theoretical and experimental results show that this algorithm can estimate the quality of images effectively and is in well consistency with the traditional objective evaluation algorithm.

  16. QC-Chain: fast and holistic quality control method for next-generation sequencing data.

    Directory of Open Access Journals (Sweden)

    Qian Zhou

    Full Text Available Next-generation sequencing (NGS technologies have been widely used in life sciences. However, several kinds of sequencing artifacts, including low-quality reads and contaminating reads, were found to be quite common in raw sequencing data, which compromise downstream analysis. Therefore, quality control (QC is essential for raw NGS data. However, although a few NGS data quality control tools are publicly available, there are two limitations: First, the processing speed could not cope with the rapid increase of large data volume. Second, with respect to removing the contaminating reads, none of them could identify contaminating sources de novo, and they rely heavily on prior information of the contaminating species, which is usually not available in advance. Here we report QC-Chain, a fast, accurate and holistic NGS data quality-control method. The tool synergeticly comprised of user-friendly tools for (1 quality assessment and trimming of raw reads using Parallel-QC, a fast read processing tool; (2 identification, quantification and filtration of unknown contamination to get high-quality clean reads. It was optimized based on parallel computation, so the processing speed is significantly higher than other QC methods. Experiments on simulated and real NGS data have shown that reads with low sequencing quality could be identified and filtered. Possible contaminating sources could be identified and quantified de novo, accurately and quickly. Comparison between raw reads and processed reads also showed that subsequent analyses (genome assembly, gene prediction, gene annotation, etc. results based on processed reads improved significantly in completeness and accuracy. As regard to processing speed, QC-Chain achieves 7-8 time speed-up based on parallel computation as compared to traditional methods. Therefore, QC-Chain is a fast and useful quality control tool for read quality process and de novo contamination filtration of NGS reads, which could

  17. Analytical Quality by Design Approach to Test Method Development and Validation in Drug Substance Manufacturing

    Directory of Open Access Journals (Sweden)

    N. V. V. S. S. Raman

    2015-01-01

    Full Text Available Pharmaceutical industry has been emerging rapidly for the last decade by focusing on product Quality, Safety, and Efficacy. Pharmaceutical firms increased the number of product development by using scientific tools such as QbD (Quality by Design and PAT (Process Analytical Technology. ICH guidelines Q8 to Q11 have discussed QbD implementation in API synthetic process and formulation development. ICH Q11 guidelines clearly discussed QbD approach for API synthesis with examples. Generic companies are implementing QbD approach in formulation development and even it is mandatory for USFDA perspective. As of now there is no specific requirements for AQbD (Analytical Quality by Design and PAT in analytical development from all regulatory agencies. In this review, authors have discussed the implementation of QbD and AQbD simultaneously for API synthetic process and analytical methods development. AQbD key tools are identification of ATP (Analytical Target Profile, CQA (Critical Quality Attributes with risk assessment, Method Optimization and Development with DoE, MODR (method operable design region, Control Strategy, AQbD Method Validation, and Continuous Method Monitoring (CMM. Simultaneous implementation of QbD activities in synthetic and analytical development will provide the highest quality product by minimizing the risks and even it is very good input for PAT approach.

  18. Methodical approaches to assessment of quality of the bank loan portfolio

    Directory of Open Access Journals (Sweden)

    Tysyachna Yunna S.

    2014-01-01

    Full Text Available The goal of the article lies in the study of basic methodical approaches to assessment of the quality of the bank loan portfolio, identification of specific features of their practical application and justification of selection of the most appropriate for the modern economic conditions. The article considers three main groups of methods of assessment of the quality of the bank loan portfolio: expert evaluation methods and statistical and analytical methods. It goes without saying that in order to obtain an objective assessment of quality of the bank loan portfolio it is necessary to apply a complex approach, however, due to some advantages and shortcomings of the studied methods, the author marks expediency of building an integral indicator, taxonomic in particular, in order to obtain a complex, objective and efficient assessment of the bank loan portfolio. Prospects of further studies in this direction are assessment of the quality of the loan portfolio of the first group banks by the size of their assets through building integral taxonomic indicators and identification, on this basis, of factors that influence the quality of the loan portfolio with the aim of improvement of the mechanism of management of the bank lending activity.

  19. METHOD OF ASSESSMENT OF QUALITY OF DIABETES CARE WITH QUESTIONNAIRE FOR DOCTORS

    Directory of Open Access Journals (Sweden)

    V. I. Tkachenko

    2015-05-01

    Full Text Available The assessment of results of new guidelines’ implementation in type 2 diabetes and quality of care is actual in Ukraine. The aim of our research is to develop a simple methodology for assessing the quality of diabetes care during new diabetes guideline implementation in Ukraine. Materials and Methods. We conducted a systematic review of S6 Ukrainian and 148 foreign literature in assessment of diabetes care, quality indicators, based on which our method was formed, its approbation was held. Statistical analysis was performed using Excel 2007, SPSS, Statistica 6.0. Results. We have developed a questionnaire by adapting existing English-language questionnaire GUIDANCE to Ukrainian health care system and added questions about knowledge and results of implementation new Ukrainian guidelines in diabetes care. The validation of questionnaire included expertise on content validity, reliability (Cronbach’s alpha level = 0.87, the sensitivity (0.7 and specificity (0.82. The method consists of use developed questionnaire for doctors in conjunction with the data of statistical reports and valid versions of questionnaires for diabetes patients ADDQoL DTSQ. The example of application of this method for assessment the quality of diabetes care is described and was informative. The proposed method allows to analyze all aspects of the quality of diabetes care.

  20. Room for improvement? Leadership, innovation culture and uptake of quality improvement methods in general practice.

    Science.gov (United States)

    Apekey, Tanefa A; McSorley, Gerry; Tilling, Michelle; Siriwardena, A Niroshan

    2011-04-01

    Leadership and innovation are currently seen as essential elements for the development and maintenance of high-quality care. Little is known about the relationship between leadership and culture of innovation and the extent to which quality improvement methods are used in general practice. This study aimed to assess the relationship between leadership behaviour, culture of innovation and adoption of quality improvement methods in general practice. Self-administered postal questionnaires were sent to general practitioner quality improvement leads in one county in the UK between June and December 2007. The questionnaire consisted of background information, a 12-item scale to assess leadership behaviour, a seven-dimension self-rating scale for culture of innovation and questions on current use of quality improvement tools and techniques. Sixty-three completed questionnaires (62%) were returned. Leadership behaviours were not commonly reported. Most practices reported a positive culture of innovation, featuring relationship most strongly, followed by targets and information but rated lower on other dimensions of rewards, risk and resources. There was a significant positive correlation between leadership behaviour and the culture of innovation (r = 0.57; P quality improvement methods were not adopted by most participating practices. Leadership behaviours were infrequently reported and this was associated with a limited culture of innovation in participating general practices. There was little use of quality improvement methods beyond clinical and significant event audit. Practices need support to enhance leadership skills, encourage innovation and develop quality improvement skills if improvements in health care are to accelerate. © 2010 Blackwell Publishing Ltd.

  1. A modified method for isolating mouse islets of an adequate quality, quantity, and purity.

    Science.gov (United States)

    Xu, Jiejie; Peng, Baogang; Zhang, Caiyun; Xu, Jiwei; Ma, Yi; Lu, Xinjun

    2017-08-01

    Mouse islets are widely used in diabetes research. Thus an adequate quality, quantity, and purity of islets are needed for high-quality investigations. We performed a combination of filtration and density gradient separation and optimized many steps in the islet isolation procedure, including perfusion, digestion, and purification. Our results show that an increased quality, quantity, and purity of isolated islets can be achieved using these modifications. Moreover, this method can guarantee maximal recovery and purity of the isolated islets and is easy to perform with practice.

  2. Assessing soil quality for sustainable agricultural systems in tropical countries using spectroscopic methods

    OpenAIRE

    Jintaridth, B.; Motavalli, Peter P.; Goyne, K.W.; Kremer, R. J.

    2008-01-01

    Soil quality assessment is a process by which soil resources are evaluated on the basis of soil function. The need for an effective, low-cost method to evaluate soil quality is important in developing countries because soil degradation is a major impediment to sustainable crop growth. Soil organic matter (SOM) or soil organic C (SOC) is an important indicator of soil quality (Gregorich et al., 1994) because it affects many plant growth factors, including water-holding capacity and long-term n...

  3. Effects of Post-Thermal Treatment on Quality of SiC Grown by PVT Method

    Institute of Scientific and Technical Information of China (English)

    ZHU Li-Na; CHEN Xiao-Long; YANG Hui; PENG Tong-Hua; NI Dai-Qin; HU Bo-Qing

    2006-01-01

    @@ We report the effects of post-thermal treatment on the quality of 2-inch 6H-SiC wafer cut from a crystal boule grown by physical vapour transportation method. The full widths at half maximum of x-ray diffraction rocking curves measured on sites across the 2-inch wafer become narrower, indicating the quality improvement after a three-step post-thermal treatment. It is found that the most common defects such as micropipes and inclusions can be significantly reduced after the treatment. Our results show that the post-thermal treatment is an effective route to improve the quality of SiC single crystals.

  4. APPLICATION OF QUALITY INDEX METHOD (QIM SCHEME IN SHELFLIFE STUDY OF ANGLERFISH (Lophius piscatorius

    Directory of Open Access Journals (Sweden)

    L. Pennisi

    2011-01-01

    Full Text Available The aim was to evaluate a Quality Index Method (QIM scheme for fresh Anglerfish (Lophius piscatorius. Anglerfish were stored at 0±2 °C on ice up to 9 days. Total Mesophilic Counts (TMC, Total Psychrophilic Counts (TPC and counts of Specific Spoilage Organisms (SSOs were done. An high correlation between the Quality Index (QI and storage time on ice and between the Quality Index (QI and H2S-producing bacteria counts was found. The remaining storage time could be estimated with accuracy of ±1.5 days when the Anglerfish were evaluated with QIM.

  5. New Measurement Method and Uncertainty Estimation for Plate Dimensions and Surface Quality

    Directory of Open Access Journals (Sweden)

    Salah H. R. Ali

    2013-01-01

    Full Text Available Dimensional and surface quality for plate production control is facing difficult engineering challenges. One of these challenges is that plates in large-scale mass production contain geometric uneven surfaces. There is a traditional measurement method used to assess the tile plate dimensions and surface quality based on standard specifications: ISO-10545-2: 1995, EOS-3168-2: 2007, and TIS 2398-2: 2008. A proposed measurement method of the dimensions and surface quality for ceramic oblong large-scale tile plate has been developed compared to the traditional method. The strategy of new method is based on CMM straightness measurement strategy instead of the centre point in the traditional method. Expanded uncertainties budgets in the measurements of each method have been estimated in detail. The capability of accurate estimations of real actual results for centre of curvature (CC, centre of edge (CE, warpage (W, and edge crack defects parameters has been achieved according to standards. Moreover, the obtained results not only showed better accurate new method but also improved the quality of plate products significantly.

  6. Acceptance Threshold: A Bidimensional Research Method for User-Oriented Quality Evaluation Studies

    Directory of Open Access Journals (Sweden)

    S. Jumisko-Pyykkö

    2008-01-01

    Full Text Available Subjective quality evaluation is widely used to optimize system performance as a part of end-products. It is often desirable to know whether a certain system performance is acceptable, that is, whether the system reaches the minimum level to satisfy user expectations and needs. The goal of this paper is to examine research methods for assessing overall acceptance of quality in subjective quality evaluation methods. We conducted three experiments to develop our methodology and test its validity under heterogeneous stimuli in the context of mobile television. The first experiment examined the possibilities of using a simplified continuous assessment method for assessing overall acceptability. The second experiment explored the boundary between acceptable and unacceptable quality when the stimuli had clearly detectable differences. The third experiment compared the perceived quality impacts of small differences between the stimuli close to the threshold of acceptability. On the basis of our results, we recommend using a bidimensional retrospective measure combining acceptance and satisfaction in consumer-/user-oriented quality evaluation experiments.

  7. KNOWLEDGE AND APPLICATION OF METHODS AND SYSTEMS QUALITY ASSURANCE IN ORCHARD FARMS IN POLAND

    Directory of Open Access Journals (Sweden)

    Eugenia Czernyszewicz

    2013-06-01

    Full Text Available Poland is significant producer of fruits in Europe. After accession to the EU, fruit producers are obligated to comply with operative rules and standards on this market which are related to ensuring commercial and healthcare products of appropriate quality. The quality of fruits available on the market is varied. This results from the fact that in the past, in domestic horticulture, more attention was paid to enlargement of the acreage, the modernization of orchards, increasing the intensity of production and productivity than on issues related to certification and quality management systems. Therefore, the aim of the work was to show the producer's opinion on methods and systems which assure quality of fruits. It was stated that producers have a good knowledge of the methods and systems of fruit quality assurance. Knowledge of these issues is significantly associated with the scale of the fruit production. The knowledge of the principles of integrated fruit production and trading standards GLOBALG.A.P. was declared most often. These methods of quality assurance were also top rated by producers and implemented mostly in farms.

  8. Comparing the soil quality changes of different land uses determined by two quantitative methods

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    Soil quality is one of the most important environmental factors in sustaining the global biosphere and developing sustainableagricultural practices.A study was initiated in Wolong Nature Reserve, Sichuan Province, China to elucidate the soil quality changes of naturalsecondary succession, forest planting and agricultural practices after deforestation in the humid mountainous region.The soil qualities of six landuse types (natural forestland, grassland, shrub land, secondary forestland, cultivated land and reforested land) were compared using twoquantitative methods: the integrated soil quality index(QI) and soil deterioration index( DI).The QI values of natural forestland, grassland,shrub land, secondary forestland, cultivated land, reforested land were 0.8039, 0.3277, 0.9127, 0.6881, 0.0285 and 0.3183, respectively.The DI values were 0%, - 14%, 12%, 1%, - 26% and - 18% respectively.Both indexes suggested that shrub land can restore soilproperties.To compare the two methods more directly, a deduced index QI' based on QI value was developed.The results showed that DI andQI' had a very high linear correlation coefficient (r = 0.9775) despite the values were different.Both methods were efficient in evaluating thesoil quality levels and DI was a more simple way in soil quality assessment, while QI could show more ecological meanings.

  9. Natural drying methods to promote fuel quality enhancement of small energywood stems

    Energy Technology Data Exchange (ETDEWEB)

    Roeser, D.; Erkkilae, A; Mola-Yudego, B. (and others)

    2010-07-01

    Due to fluctuating fossil fuel prices the use of forest biomass for energy is expected to increase considerably in the future. Today, the demand for high quality wood fuel products such as chopped firewood or pellets has increased price pressure on these products. In order to make the production more cost-effective new methods to optimize their production have to be found. Drying of raw material in the forest in order to improve the quality of the raw material and to reduce transportation costs can considerably improve the overall efficiency of the supply chain. It also enables longer storing periods and decreases GHG emissions and dry matter losses during storing. The purpose of the study was to test natural drying and the effect of different degrees of partial debarking and different methods of bark scarifying as well as covering on natural drying of energywood stems. The test included laboratory tests in Finland and field trials in Finland, Scotland and Italy, using local practices and forest species commonly used as a raw material for different forest energy products. In the laboratory test for birch, partial debarking and scarifying can be as effective drying accelerants as traditional splitting. It is important that scarifying is done all over the stem. During the test, untreated stems were drying from original 48% of moisture down to 35% during 6 months of drying between March and September. During the same period, split, partially debarked and scarified stems achieved more than 10%-units lower moisture. With pine, scarifying does not work as effectively with small percentages of removed or scarified bark. According to the results of the field trials, the debarking using a harvester head had a significant effect on moisture content decrease during the drying season especially when the stacks were covered. Covering is more vital in rainier circumstances, but nevertheless there are also notable differences between tree species. The results show that the tested

  10. Effect of Drying Methods on the Chemical Quality Traits of Cocoa Raw Material

    Directory of Open Access Journals (Sweden)

    G. Irie B. Zahouli

    2010-07-01

    Full Text Available This study concerns the measurement of some chemical quality properties of raw cocoa dried by solar and heating methods. Sun drying method is considered as standard process. Drying trials were conducted in thin layer using natural sun light drying method, heating methods by exposition of the beans to hot air ventilated oven at 60ºC and in sun light consecutive artificial drying methods. Changes in volatile acidity on the drying method were not very clear. Only sun and mixed dried raw cocoa showed a high volatile acidity. Oven and mixed drying methods have caused higher free acidity and higher Ammonium Nitrogen content in raw cocoa than natural drying methods. Changes in Ammonium Nitrogen in fermented appeared significantly due to the ferm entation. Also all studied drying processes did not influence the production of free fatty acids in raw cocoa. The results obtained from this study are essential in understanding and solving the problems associated with the final quality of raw cocoa material dependent on the drying methods. Better quality of raw cocoa material could be resulted from natural drying process than heating methods.

  11. Comparison of bar pattern and edge method for MTF measurement in radiology quality control

    Energy Technology Data Exchange (ETDEWEB)

    Alvarez, M.; Alves, A.F.F; Bacchim Neto, F.A.; Pavan, A.L.M.; Rosa, M.E.D.; Miranda, J.R.A.; Pina, D.R. de, E-mail: drpina@fmb.unesp.br [Universidade Estadual Paulista Julio de Mesquita Filho (UNESP), Botucatu, SP (Brazil)

    2015-08-15

    Spatial resolution is one of the parameters that is routinely checked during acceptance procedures and regular quality control measurements. The spatial resolution of a radiographic imaging device is most appropriately expressed in terms of its modulation transfer function (MTF), which indicates the decline of detector spatial resolution with spatial frequency. Traditionally used methods of MTF measurement involve imaging either a narrow slit or a sharp edge to obtain the detector line spread function (LSF), whose frequency transform leads to the MTF. In this work is presented a study of the measurement of the limiting spatial resolution using the MTF method and the line-pair bar-pattern method. Our aim is to compare the bar-pattern method with the MTF method and then evaluate what method is the best for the dairy quality control tests and when is better to perform one test or other. These acquisition procedures were tested according to its reproducibility and variation due to noise. (author)

  12. R/S method for evaluation of pollutant time series in environmental quality assessment

    Institute of Scientific and Technical Information of China (English)

    Bu Quanmin; Bi Jun; Yuan Zengwei; Huang Lei

    2008-01-01

    The significance of the fluctuation and randomness of the time series of each pollutant in environmental quality assessment is described for the first time in this paper. A comparative study was made of three different computing methods: the same starting point method, the striding averaging method, and the stagger phase averaging method. All of them can be used to calculate the Hurst index, which quantifies fluctuation and randomness. This study used real water quality data from Shazhu monitoring station on Taihu Lake in Wuxi, Jiangsu Province. The results show that, of the three methods, the stagger phase averaging method is best for calculating the Hurst index of a pollutant time series from the perspective of statistical regularity.

  13. Combining qualitative and quantitative operational research methods to inform quality improvement in pathways that span multiple settings.

    Science.gov (United States)

    Crowe, Sonya; Brown, Katherine; Tregay, Jenifer; Wray, Jo; Knowles, Rachel; Ridout, Deborah A; Bull, Catherine; Utley, Martin

    2017-08-01

    Improving integration and continuity of care across sectors within resource constraints is a priority in many health systems. Qualitative operational research methods of problem structuring have been used to address quality improvement in services involving multiple sectors but not in combination with quantitative operational research methods that enable targeting of interventions according to patient risk. We aimed to combine these methods to augment and inform an improvement initiative concerning infants with congenital heart disease (CHD) whose complex care pathway spans multiple sectors. Soft systems methodology was used to consider systematically changes to services from the perspectives of community, primary, secondary and tertiary care professionals and a patient group, incorporating relevant evidence. Classification and regression tree (CART) analysis of national audit datasets was conducted along with data visualisation designed to inform service improvement within the context of limited resources. A 'Rich Picture' was developed capturing the main features of services for infants with CHD pertinent to service improvement. This was used, along with a graphical summary of the CART analysis, to guide discussions about targeting interventions at specific patient risk groups. Agreement was reached across representatives of relevant health professions and patients on a coherent set of targeted recommendations for quality improvement. These fed into national decisions about service provision and commissioning. When tackling complex problems in service provision across multiple settings, it is important to acknowledge and work with multiple perspectives systematically and to consider targeting service improvements in response to confined resources. Our research demonstrates that applying a combination of qualitative and quantitative operational research methods is one approach to doing so that warrants further consideration. Published by the BMJ Publishing Group

  14. The Nordic Housing Enabler

    DEFF Research Database (Denmark)

    Helle, Tina; Slaug, Bjørn; Brandt, Åse

    2010-01-01

    This study addresses development of a content valid cross-Nordic version of the Housing Enabler and investigation of its inter-rater reliability when used in occupational therapy rating situations, involving occupational therapists, clients and their home environments. The instrument was translated...... from the original Swedish version of the Housing Enabler, and adapted according to accessibility norms and guidelines for housing design in Sweden, Denmark, Finland and Iceland. This iterative process involved occupational therapists, architects, building engineers and professional translators......, resulting in the Nordic Housing Enabler. For reliability testing, the sampling strategy and data collection procedures used were the same in all countries. Twenty voluntary occupational therapists, pair-wise but independently from each other, collected data from 106 cases by means of the Nordic Housing...

  15. Organising to Enable Innovation

    DEFF Research Database (Denmark)

    Brink, Tove

    2016-01-01

    . The findings reveal a continous organising process between individual/ team creativity and organisational structures/control to enable innovation at firm level. Organising provides a dynamic approach and contains the integrated reconstruction of creativity, structures and boundaries for enhanced balance......The purpose of this conceptual paper is to reveal how organising can enable innovation across organisational layers and organisational units. This approach calls for a cross-disciplinary literature review. The aim is to provide an integrated understanding of innovation in an organisational approach...... of explorative and exploitative learning in uncertain environments. Shedding light on the cross-disciplinary theories to organise innovation provides a contribution at the firm level to enable innovation....

  16. [Identification of special quality eggs with NIR spectroscopy technology based on symbol entropy feature extraction method].

    Science.gov (United States)

    Zhao, Yong; Hong, Wen-Xue

    2011-11-01

    Fast, nondestructive and accurate identification of special quality eggs is an urgent problem. The present paper proposed a new feature extraction method based on symbol entropy to identify near infrared spectroscopy of special quality eggs. The authors selected normal eggs, free range eggs, selenium-enriched eggs and zinc-enriched eggs as research objects and measured the near-infrared diffuse reflectance spectra in the range of 12 000-4 000 cm(-1). Raw spectra were symbolically represented with aggregation approximation algorithm and symbolic entropy was extracted as feature vector. An error-correcting output codes multiclass support vector machine classifier was designed to identify the spectrum. Symbolic entropy feature is robust when parameter changed and the highest recognition rate reaches up to 100%. The results show that the identification method of special quality eggs using near-infrared is feasible and the symbol entropy can be used as a new feature extraction method of near-infrared spectra.

  17. Balance sheet method assessment for nitrogen fertilization in bread wheat: I. yield and quality

    Directory of Open Access Journals (Sweden)

    Mario Monotti

    2011-02-01

    Full Text Available In the European Union the production of high quality wheat is mainly located in the Mediterranean regions where the climatic conditions positively affect protein concentration in the grain. High quality wheat calls for proper management of nitrogen fertilization, thus there is a need to verify whether the limitations imposed by local governments on maximum rate of nitrogen fertilization admitted may affect bread making quality. Trials were conducted in fourteen environments (E to study the effects of different nitrogen fertilizations on eight cultivars (C, belonging to four quality grades (Q. Nitrogen (N was applied to crops according to three rates/modalities: N1 corresponding to the maximum rate admitted calculated according to a balance sheet method and distributed at the stage of spike initiation; N2 with 50 kg ha-1 of nitrogen more than N1, also distributed at the stage of spike initiation; N3 with 50 kg ha-1 of nitrogen more than N1 but distributed at the stage of flag leaf appearance. The effects of environment, nitrogen and cultivar were significant for grain yield, test weight, 1000 kernel weight, heading time, plant height and for quality traits (protein content and alveograph indices. The existence of variability among cultivars and quality grades in the response to rate and timing of nitrogen fertilization was demonstrated by the significance of NxC and NxQ interactions. Dry matter and nitrogen contents of plant at anthesis and at harvest were significantly affected by the main sources of variation. High quality cultivars yielded more grain of better quality with higher N rates (N2 and N3 as compared to the maximum rate of nitrogen admitted by the local government (N1. These results demonstrated that the adopted balance sheet method for the calculation of N requirements of wheat crop adversely affects the full potential expression of the cultivars belonging to superior bread making quality grades.

  18. Development of the new physical method for real time spot weld quality evaluation using ultrasound

    Science.gov (United States)

    Chertov, Andriy M.

    Since the invention of resistance spot welding, the manufacturers have been concerned about the quality assurance of the joints. One of the most promising directions in quality inspection is the real time ultrasonic nondestructive evaluation. In such a system, the acoustic signals are sent through the spot weld during welding and then analyzed to characterize the quality of the joint. Many research groups are currently working to develop a reliable inspection method. In this dissertation the new physical method of resistance spot weld quality monitoring is presented. It differs from all other ultrasonic methods by the physical principles of inspection. The multilayered structure of the spot weld with varying physical properties is investigated with short pulses of longitudinal ultrasonic waves. Unlike other methods, the developed technology works in reflection mode. The waves bring back the information which, after careful analysis, can be used to evaluate the weld quality. The complex structure of the weldment modifies the waves in different ways which, makes it hard to accurately measure the physical properties of the weldment. The frequency-dependent attenuation of the sound, diffraction, and beam divergence - all contribute to the signal distraction. These factors are fully studied, and ways to minimize them are presented. After application of pattern recognition routines, the weld characteristics are submitted to fuzzy logic algorithm, and the weld is characterized. The current level of the system development allowed the installation of two prototype machines at one assembly plant. The technology is now under thorough evaluation for robustness and accuracy in an industrial environment.

  19. Using the Deming quality improvement method to manage medical record department product lines.

    Science.gov (United States)

    Postal, S N

    1990-06-01

    The above application of the quality improvement cycle provides insight into the use of the Deming method to address one of several identified customer needs and expectations obtained during the managing phase of product-line administration. Implementation of the quality improvement method requires a major commitment from all team members. Process improvement requires a willingness to be detail oriented. Gathering of statistics--such as analysis turn-around time--and evaluation are critical. This objective view of processes requires accountability and a commitment to change. Improvements focus on long-term problem resolution, not the quick fixes that result from addressing symptoms of problems. True problem resolution occurs by solving the root causes of variations. Medical record departments must move from being outcome oriented to being process focused. It is no longer feasible to be constantly putting out fires in an environment that demands well-planned and well-designed products that meet customers' expectations. The long-term management of product lines requires a systematic method of planning, doing, checking, and acting. The Deming quality improvement method provides a framework for positive change that focuses on quality processes resulting in a quality product that meets consumers' needs.

  20. IR image quality assessment and real-time optimum seeking method based on dynamic visual characteristics

    Science.gov (United States)

    Li, Bin; Liu, Gang; Gao, Yongmin; Lei, Hao; Wu, Haiying; Wang, Yu; Rong, Xiaolong

    2016-10-01

    Image quality is an important factor that influences the dynamic target information perception; it is the key factor of real-time target state analysis and judgment. In order to solve the multi-observation station comparison and video optimum seeking problem in the process of target information perception and recognition, an image quality assessment method based on visual characteristics is proposed for infrared target tracking. First, it analyses the basic infrared target image characteristics and application requirements, analyses the status and problems of the multi station optimum seeking technology. According to the expected research results, the processing flow of image processing is established. Then, the image quality objective assessment index is established, which reflects the basic characteristics of the target image, and the assessment index is integrated into the normalized assessment function. According to the quality assessment function, the infrared image quality assessment based on infrared target recognition and image analysis processing is realized, which is mainly characterized by the region of interest and dynamic visual characteristics. And on the basis of this technology, the real-time optimum seeking of multi station infrared target tracking image is completed. In order to verify the effectiveness of the method and the practical application effect, it designs the quality assessment and comparison of different station infrared images. Example shows that the method proposed in this paper can realize multi-observation station infrared image assessment comparison, image quality sorting, the optimum seeking of the infrared image based on the quality assessment. The results accord with the characteristics of infrared target image and dynamic visual characteristics.

  1. New Method For Modeling and Design Optical SDM Transmission System Using Long Haul FMF with PDM/DWDM Techniques Enabling QPSK Modulation Format

    Directory of Open Access Journals (Sweden)

    Ibrahim Abdullah

    2017-07-01

    Full Text Available This paper presents the modeling and design of ultra high capacity Space Division Multiplexing (SDM transmission system. Polarization Division Multiplexing (PDM and Dense Wavelength Division Multiplexing (DWDM techniques are also proposed in this system to increase total system data rate. For the ultra-high capacity need of SDM, Few Mode Fiber (FMF was proposed as SDM best technology for obtaining ultra-high bit rates with long haul transmission. The description and design of 8-DWDM channels over 7 modes SDM/PDM system was explored as future of ultra-high capacity optical network. A long-haul transmission of 1080 Km recorded for 8-WDM channels-7modes-SDM/PDM system by using QPSK modulation format. The total bit rate achieved by our designed system is 4.48 Tb/s at 40Gb/s. Channel estimation techniques were proposed to enable the transmitter pre-shaping design for the linear effects mitigation by using different DSP algorithms. The presence of linear and nonlinear losses limits the acceptable range of input power that produce the required BER for our proposed system from -4dBm to 4dBm.

  2. Analysis of flexible aircraft longitudinal dynamics and handling qualities. Volume 1: Analysis methods

    Science.gov (United States)

    Waszak, M. R.; Schmidt, D. S.

    1985-01-01

    As aircraft become larger and lighter due to design requirements for increased payload and improved fuel efficiency, they will also become more flexible. For highly flexible vehicles, the handling qualities may not be accurately predicted by conventional methods. This study applies two analysis methods to a family of flexible aircraft in order to investigate how and when structural (especially dynamic aeroelastic) effects affect the dynamic characteristics of aircraft. The first type of analysis is an open loop model analysis technique. This method considers the effects of modal residue magnitudes on determining vehicle handling qualities. The second method is a pilot in the loop analysis procedure that considers several closed loop system characteristics. Volume 1 consists of the development and application of the two analysis methods described above.

  3. Reliable evaluation method of quality control for compressive strength of concrete

    Institute of Scientific and Technical Information of China (English)

    CHEN Kuen-suan; SUNG Wen-pei; SHIH Ming-hsiang

    2005-01-01

    Concrete in reinforced concrete structure (RC) is generally under significant compressive stress load. To guarantee required quality and ductility, various tests have to be conducted to measure the concrete's compressive strength based on ACI(American Concrete Institute) code. Investigations of recent devastating collapses of structures around the world showed that some of the collapses directly resulted from the poor quality of the concrete. The lesson learned from these tragedies is that guaranteeing high quality of concrete is one of the most important factors ensuring the safety of the reinforced concrete structure.In order to ensure high quality of concrete, a new method for analyzing and evaluating the concrete production process is called for.In this paper, the indices of fit and stable degree are proposed as basis to evaluate the fitness and stability of concrete's compressive strength. These two indices are combined to define and evaluate the quality index of the compressive strength of concrete. Principles of statistics are used to derive the best estimators of these indices. Based on the outcome of the study, a concrete compressive strength quality control chart is proposed as a tool to help the evaluation process. Finally, a new evaluation procedure to assess the quality control capability of the individual concrete manufacturer is also proposed.

  4. Challenges of Using Quality Improvement Methods in Nursing Homes that “Need Improvement”

    Science.gov (United States)

    Rantz, Marilyn J.; Zwygart-Stauffacher, Mary; Flesner, Marcia; Hicks, Lanis; Mehr, David; Russell, Teresa; Minner, Donna

    2012-01-01

    A randomized, two-group, repeated-measures design was used to test a two year intervention for improving quality of care and resident outcomes in facilities in “need of improvement”. Intervention group (n=29) received an experimental multilevel intervention designed to help them (1) use quality-improvement methods, (2) use team and group process for direct-care decision-making, (3) focus on accomplishing the basics of care, and (4) maintain more consistent nursing and administrative leadership committed to communication and active participation of staff in decision-making. A qualitative analysis revealed a subgroup of homes likely to continue quality improvement activities and readiness indicators of homes likely to improve 1) leadership team (NHA, DON) who are interested in learning to use their federal Quality Indicator/Quality Measure (QI/QM) reports to improve resident care and outcomes; 2) one leader who will be the “change champion” and others make sure that current QI/QM reports are consistently shared on each nursing unit; 3) willingness to involve all staff in educational activities to learn about the QI/QM process and federal reports that compare the home with others in the state and nation; 4) plan and continuously educate new staff about the QI/QM process and how to do quality improvement; 5) continuously involve all staff in quality improvement committee and team activities so they “own” the process and are responsible for change. PMID:22926322

  5. Development of an integrated method for long-term water quality prediction using seasonal climate forecast

    Science.gov (United States)

    Cho, Jaepil; Shin, Chang-Min; Choi, Hwan-Kyu; Kim, Kyong-Hyeon; Choi, Ji-Yong

    2016-10-01

    The APEC Climate Center (APCC) produces climate prediction information utilizing a multi-climate model ensemble (MME) technique. In this study, four different downscaling methods, in accordance with the degree of utilizing the seasonal climate prediction information, were developed in order to improve predictability and to refine the spatial scale. These methods include: (1) the Simple Bias Correction (SBC) method, which directly uses APCC's dynamic prediction data with a 3 to 6 month lead time; (2) the Moving Window Regression (MWR) method, which indirectly utilizes dynamic prediction data; (3) the Climate Index Regression (CIR) method, which predominantly uses observation-based climate indices; and (4) the Integrated Time Regression (ITR) method, which uses predictors selected from both CIR and MWR. Then, a sampling-based temporal downscaling was conducted using the Mahalanobis distance method in order to create daily weather inputs to the Soil and Water Assessment Tool (SWAT) model. Long-term predictability of water quality within the Wecheon watershed of the Nakdong River Basin was evaluated. According to the Korean Ministry of Environment's Provisions of Water Quality Prediction and Response Measures, modeling-based predictability was evaluated by using 3-month lead prediction data issued in February, May, August, and November as model input of SWAT. Finally, an integrated approach, which takes into account various climate information and downscaling methods for water quality prediction, was presented. This integrated approach can be used to prevent potential problems caused by extreme climate in advance.

  6. Towards a standardized method of developing quality indicators for palliative care: protocol of the Quality indicators for Palliative Care (Q-PAC) study.

    NARCIS (Netherlands)

    Leemans, K.; Cohen, J.; Francke, A.L.; Stichele, R. Vander; Claessen, S.J.J.; Block, L. van den; Deliens, L.

    2013-01-01

    Background: In recent years, there have been several studies, using a wide variety of methods, aimed at developing quality indicators for palliative care. In this Quality Indicators for Palliative Care study (Q-PAC study) we have applied a scientifically rigorous method to develop a comprehensive an

  7. Towards a standardized method of developing quality indicators for palliative care: protocol of the Quality indicators for Palliative Care (Q-PAC) study.

    NARCIS (Netherlands)

    Leemans, K.; Cohen, J.; Francke, A.L.; Stichele, R. Vander; Claessen, S.J.J.; Block, L. van den; Deliens, L.

    2013-01-01

    Background: In recent years, there have been several studies, using a wide variety of methods, aimed at developing quality indicators for palliative care. In this Quality Indicators for Palliative Care study (Q-PAC study) we have applied a scientifically rigorous method to develop a comprehensive

  8. Enabling Global Collaboration

    DEFF Research Database (Denmark)

    Brix, Anders; de Gier, Nicolai

    2014-01-01

    recognizing the value of incremental refinement of tradition and sustainability obtained through cultivation of the culturally and visually sustainable. As a contribution to this development, we propose: 1) The notion of tectonics as a core concept enabling a mutual, cross-cultural design discourse...

  9. The Nordic Housing Enabler

    DEFF Research Database (Denmark)

    Helle, T.; Nygren, C.; Slaug, B.

    2014-01-01

    This study addresses development of a content-valid cross-Nordic version of the Housing Enabler and investigation of its inter-rater reliability when used in occupational therapy rating situations, involving occupational therapists, clients, and their home environments. The instrument was transla......This study addresses development of a content-valid cross-Nordic version of the Housing Enabler and investigation of its inter-rater reliability when used in occupational therapy rating situations, involving occupational therapists, clients, and their home environments. The instrument...... was translated from the original Swedish version of the Housing Enabler, and adapted according to accessibility norms and guidelines for housing design in Sweden, Denmark, Finland, and Iceland. This iterative process involved occupational therapists, architects, building engineers, and professional translators......, resulting in the Nordic Housing Enabler. For reliability testing, the sampling strategy and data collection procedures used were the same in all countries. Twenty voluntary occupational therapists, pair-wise but independently of each other, collected data from 106 cases by means of the Nordic Housing...

  10. Enabling distributed collaborative science

    DEFF Research Database (Denmark)

    Hudson, T.; Sonnenwald, Diane H.; Maglaughlin, K.

    2000-01-01

    To enable collaboration over distance, a collaborative environment that uses a specialized scientific instrument called a nanoManipulator is evaluated. The nanoManipulator incorporates visualization and force feedback technology to allow scientists to see, feel, and modify biological samples being...... studied with an Atomic Force Microscope....

  11. Pilot project as enabler?

    DEFF Research Database (Denmark)

    Neisig, Margit; Glimø, Helle; Holm, Catrine Granzow;

    This article deals with a systemic perspective on transition. The field of study addressed is a pilot project as enabler of transition in a highly complex polycentric context. From a Luhmannian systemic approach, a framework is created to understand and address barriers of change occurred using p...

  12. Enabling distributed collaborative science

    DEFF Research Database (Denmark)

    Hudson, T.; Sonnenwald, Diane H.; Maglaughlin, K.

    2000-01-01

    To enable collaboration over distance, a collaborative environment that uses a specialized scientific instrument called a nanoManipulator is evaluated. The nanoManipulator incorporates visualization and force feedback technology to allow scientists to see, feel, and modify biological samples bein...

  13. Ranking Parameters on Quality of Online Shopping Websites Using Multi-Criteria Method

    Directory of Open Access Journals (Sweden)

    Mehrbakhsh Nilashi

    2012-11-01

    Full Text Available The growing use of Internet in Malaysia provides a developing prospect of online shopping for international students. Also, international students are an outstanding group in online shopping in Malaysia. In view of this, in order to improve increase online shopping among international students and Malaysian online shopping, a research framework was proposed and a survey of international student was done. Proposed research framework considers three key dimensions service quality, information quality and system quality for online shopping website. To gather initial data, international students of UTM were asked. Data was collected from 300 international students of UTM. Using normal TOPSIS and fuzzy- TOPSIS approaches all parameters in hierarchy were ranked. Our findings demonstrated that using fuzzy- TOPSIS method trust, response time, reliability, responsiveness, empathy, timeliness, accuracy of information, navigation and accessibility are the nine first important parameters in online website quality.

  14. Apparatus and method for acoustic monitoring of steam quality and flow

    Energy Technology Data Exchange (ETDEWEB)

    Sinha, Dipen N.; Pantea, Cristian

    2016-09-13

    An apparatus and method for noninvasively monitoring steam quality and flow and in pipes or conduits bearing flowing steam, are described. By measuring the acoustic vibrations generated in steam-carrying conduits by the flowing steam either by direct contact with the pipe or remotely thereto, converting the measured acoustic vibrations into a frequency spectrum characteristic of the natural resonance vibrations of the pipe, and monitoring the amplitude and/or the frequency of one or more chosen resonance frequencies, changes in the steam quality in the pipe are determined. The steam flow rate and the steam quality are inversely related, and changes in the steam flow rate are calculated from changes in the steam quality once suitable calibration curves are obtained.

  15. USE OF THE SERVPERF METHOD TO EVALUATE SERVICE QUALITY IN THE TRANSPORT COMPANY

    Directory of Open Access Journals (Sweden)

    Manuela Krystyna Ingaldi

    2016-03-01

    Full Text Available Transport services are one of the most common services in Poland and abroad. Especially passenger transport is very popular. For those without a car or travelling in large groups, such transport is a big convenience. On the market there are many companies that offer this kind of services. Decisions about the particular service provider shall be based on own experiences of customer, opinions of others people and quality analysis results which are often available on many different websites. In such quality analysis special types of methods are used, among which the Servqual method and its variation the Servperf method should be mentioned. In the article the Servperf method was used to evaluate the quality of transport services in the chosen company. In this method the customer does not evaluate his expectations for the service, but only the final service. According to the customers of the research company, its services in about 65% met their expectations. Their also indicated which determinants had the highest positive and negative impact on the quality of these services.

  16. Comprehensive quality assessment of municipal organic waste composts produced by different preparation methods.

    Science.gov (United States)

    Tognetti, C; Mazzarino, M J; Laos, F

    2011-06-01

    In the first part of this work, the effect of municipal organic waste (MOW) composts on plant growth was evaluated in a greenhouse trial. The treatments included soil amended with 14 different composts (prepared by shredding, adding wood shavings, cocomposting with biosolids or vermicomposting), an inorganically fertilized soil, and a control soil. All of the treatments significantly increased plant growth compared to the control, and yields of three of the amended treatments were as high as that of the inorganic fertilizer treatment. When comparing differently prepared composts to the conventional compost, it was found that cocomposting MOW with biosolids was the method which most positively influenced yields (26-41% yield increases). In the second part of this work, we evaluated the effects of the different preparation methods on compost quality, using a multivariate approach. Three main quality aspects were considered collectively in a principal component analysis: organic matter and nutrient concentrations, degradability and capacity to mineralize these nutrients, and plant growth. The model was restricted to the first and second components (PC1 and PC1) which accounted for 94% of data variance. On the resulting factorial plane, four groups were distinguished. Each of the groups was compared to the reference compost to determine quality increases or decreases. Based on this analysis, it was found that cocomposting MOW with biosolids produced the highest quality products (higher total nutrient and OM concentration, nutrient mineralization potential, and plant growth). Addition of wood shavings increased OM concentration, but reduced quality in terms of the other aspects studied. Shredding was only effective to increase product quality when it was not combined with other methods, whereas vermicomposting only increased quality when MOW was not mixed with biosolids. Copyright © 2011 Elsevier Ltd. All rights reserved.

  17. A Comparative Analysis of Environmental Quality Assessment Methods for Heavy Metal-Contaminated Soils

    Institute of Scientific and Technical Information of China (English)

    LI Wei-Xin; ZHANG Xu-Xiang; WU Bing; SUN Shi-Lei; CHEN Yan-Song; PAN Wen-Yang; ZHAO Da-Yong; CHENG Shu-Pei

    2008-01-01

    Four assessment methods (two pollution indexes and two fuzzy mathematical models) were employed to investigate the environmental quality of four soils around a ferroalloy plant in Nanjing City.Environmental quality was assessed as class Ⅳ (moderately polluted) for each soil with single-factor index method,and was identified to be classes Ⅳ,Ⅲ(slightly polluted),Ⅲ,and Ⅲ for soils A,B,C,and D,respectively,with the comprehensive index model.In comparison with the single-factor index method,the comprehensive index model concerned both dominant parameter and average contribution of all factors to the integrated environmental quality.Using the two fuzzy mathematical methods (single-factor deciding and weighted average models),the environmental risks were determined to be classes Ⅳ,Ⅲ,Ⅱ(clean),and Ⅱ for soils A,B,C,and D,respectively.However,divergence of the membership degree to each pollution class still occurred between the two methods.In fuzzy mathematical methods,membership functions were used to describe the limits between different pollution degrees,and different weights were allocated for the factors according to pollution contribution.Introduction of membership degree and weight of each factor to fuzzy mathematical models made the methods more reasonable in the field of environmental risk assessment.

  18. Electric Sensors for Express-Method Checking of Liquid Quality Level Monitoring

    Directory of Open Access Journals (Sweden)

    Petro STOLYARCHUK

    2010-02-01

    Full Text Available The research covered in the suggested article is meant for ecological monitoring in the broad sense. The express-method of water solution quality level estimation and the technique of fast response to the quality level of industrial, agricultural and domestic wastewaters along with food products are proposed. The novelty of the proposed technique roots in the implementation of suggested methods and means of electric parameter measurement aimed at the quality index controlling of nonelectric qualimetry objects. Relevant research includes the exploration of water-solutions as well as different-level purification of industrial and domestic spillage waters, colloid solutions (cream, milk with the known contaminants, mixtures of superficially active substances and chlorine-containing substances.

  19. A Water Quality Monitoring Method Based on Fuzzy Comprehensive Evaluation in Wireless Sensor Networks

    Directory of Open Access Journals (Sweden)

    Jian Shu

    2012-01-01

    Full Text Available A novel water quality monitoring method named WQMMFCE is proposed based on fuzzy comprehensive evaluation model to solve the issue of high energy consumption caused by centralized approach under the background of water quality monitoring. The weights of all factors which are necessary for fuzzy comprehensive evaluation can be obtained firstly by using the binary expert evaluation. The information needs to transmit is decided according to water quality grade which is quantitatively analyzed directly by using fuzzy comprehensive evaluation rather than transmitting large amount of raw data to the monitoring center. Simulation result shows that the method has a great advantage over the centralized one on energy saving and can prolong the lifetime of the network.

  20. INTERVAL FINITE VOLUME METHOD FOR UNCERTAINTY SIMULATION OF TWO-DIMENSIONAL RIVER WATER QUALITY

    Institute of Scientific and Technical Information of China (English)

    HE Li; ZENG Guang-ming; HUANG Guo-he; LU Hong-wei

    2004-01-01

    Under the interval uncertainties, by incorporating the discretization form of finite volume method and interval algebra theory, an Interval Finite Volume Method (IFVM) was developed to solve water quality simulation issues for two-dimensional river when lacking effective data of flow velocity and flow quantity. The IFVM was practically applied to a segment of the Xiangjiang River because the Project of Hunan Inland Waterway Multipurpose must be started working after the environmental impact assessment for it. The simulation results suggest that there exist rather apparent pollution zones of BOD5 downstream the Dongqiaogang discharger and that of COD downstream Xiaoxiangjie discharger, but the pollution sources have no impact on the safety of the three water plants located in this river segment. Although the developed IFVM is to be perfected, it is still a powerful tool under interval uncertainties for water environmental impact assessment, risk analysis, and water quality planning, etc. besides water quality simulation studied in this paper.

  1. A Control Law Design Method Facilitating Control Power, Robustness, Agility, and Flying Qualities Tradeoffs: CRAFT

    Science.gov (United States)

    Murphy, Patrick C.; Davidson, John B.

    1998-01-01

    A multi-input, multi-output control law design methodology, named "CRAFT", is presented. CRAFT stands for the design objectives addressed, namely, Control power, Robustness, Agility, and Flying Qualities Tradeoffs. The methodology makes use of control law design metrics from each of the four design objective areas. It combines eigenspace assignment, which allows for direct specification of eigenvalues and eigenvectors, with a graphical approach for representing the metrics that captures numerous design goals in one composite illustration. Sensitivity of the metrics to eigenspace choice is clearly displayed, enabling the designer to assess the cost of design tradeoffs. This approach enhances the designer's ability to make informed design tradeoffs and to reach effective final designs. An example of the CRAFT methodology applied to an advanced experimental fighter and discussion of associated design issues are provided.

  2. HEALING THE ROMANIAN HEALTH CARE SYSTEM THROUGH THE TOTAL QUALITY MANAGEMENT METHOD

    Directory of Open Access Journals (Sweden)

    Cosmin Dobrin

    2015-07-01

    Nowadays, this method is used with success and covers a large area of industries, including the sanitary industry. European hospitals have used this method in order to rearrange, from the quality’s point of view, their departments and keep their customers and employees satisfied with the sanitary institution.Total Quality Management is a method that has the ability to convert the health care system, and to cover all “gaps” formed for several years. Starting with correcting as much as possible all the issues found in the health care system, will lead to the top and most important objective: focusing on patient and assuring him a significant level of satisfaction. The applicability of this method made is possible also for Romanian hospitals. Since our health care system is confronting daily with issues that affect the patients (some issues being even deadly, a change in the way the quality is perceived, is suitable for our hospitals and clinics.

  3. The Quality Evaluation Method of Instrument Flight Procedure Design Scheme Based on Fuzzy Linguistic Assessments

    Directory of Open Access Journals (Sweden)

    Chen Ken

    2013-07-01

    Full Text Available The quality of Instrument Flight Procedure Design Scheme (QIFPDS is directly related to the terminal area airspace capacity, quality, efficiency of air traffic management, and even the safety of aircraft. Hence, the evaluation of QIFPDS has great significance in real life. However, the evaluation of QIFPDS in real work is mainly done by experts through their specific knowledge and experience, which usually leads to a bias result and inevitably contains subjectivity and arbitrary defects. In this paper, a multi-attribute group decision-making method is proposed. This method makes full use of evaluation information; objectively and effectively evaluate QIFPDS. Also in this paper, a mathematical model for this method is introduced and a detailed step to solve this model is listed. At the end of this paper, an example is given to show the effectiveness and feasibility of the method.  

  4. Assessment on the Food Management Quality Based on the Method of Improving TOPSIS

    Directory of Open Access Journals (Sweden)

    Mengyan Wang

    2015-09-01

    Full Text Available Based on the analysis of the existing methods of evaluating foods, this study puts forward a comprehensive evaluation method for Foods quality to improve TOPSIS method, so as to avoid the problem of the scheme of the ideal solution and the negative ideal solution is too close to the problem, which can improve the scientific and reasonable feature of the traditional TOPSIS method. The development of the society has an increasing requirements for the food management quality in the future. Food management education is a public compulsory course for students who are in higher normal colleges, which is with distinctive feature of normal education and is closely related to the important course for training the qualified foods.

  5. Influence of Assist Laser Irradiation Timing on Quality of HAp Coating in LALA Method

    Science.gov (United States)

    Katayama, Hirotaka; Ishibashi, Keisuke; Dodo, Masahiro; Hashishin, Yuichi; Katto, Masahito; Nakayama, Takeyoshi

    In order to create the implant material which has high biocompatibility, a new hydroxyapatite (HAp) coating method, the laser-assisted laser ablation (LALA) method, has been developed. In this method, control of assist laser irradiation timing (delay time after an ablation laser irradiation) is very important for the quality of a HAp coating layer. We studied the influence of the timing on adhesion strength , crystallinity and Ca/P value of the HAp coating. Quality of the HAp coating layer obtained at a delay time of a few microseconds was extremely high. On the other hand, the layer obtained over 10 microseconds had more amorphous component and contained other calcium phosphate compounds from HAp. Using the present method, we succeeded in fabricating thin film (𕟽 μm) of HAp with high crystallinity.

  6. Mean-value second-order uncertainty analysis method: application to water quality modelling

    Science.gov (United States)

    Mailhot, Alain; Villeneuve, Jean-Pierre

    Uncertainty analysis in hydrology and water quality modelling is an important issue. Various methods have been proposed to estimate uncertainties on model results based on given uncertainties on model parameters. Among these methods, the mean-value first-order second-moment (MFOSM) method and the advanced mean-value first-order second-moment (AFOSM) method are the most common ones. This paper presents a method based on a second-order approximation of a model output function. The application of this method requires the estimation of first- and second-order derivatives at a mean-value point in the parameter space. Application to a Streeter-Phelps prototype model is presented. Uncertainties on two and six parameters are considered. Exceedance probabilities (EP) of dissolved oxygen concentrations are obtained and compared with EP computed using Monte Carlo, AFOSM and MFOSM methods. These results show that the mean-value second-order method leads to better estimates of EP.

  7. QSRTI: a method for quality assessment of event based (safety related) traffic information

    NARCIS (Netherlands)

    Hendriks, T.; Vliet-Hameeteman, C. van der

    2015-01-01

    Using ITS data without understanding its quality is questionable. The QSRTI method has been created by TNO on behalf of the Dutch Road Authority (RWS) in response to the European ITS action plan [1]. To reduce the number of road accidents and enhancing traffic efficiency, the European Commission has

  8. Quality Index Method developed for gutted and ungutted red tilapia (Oreochromis ssp

    Directory of Open Access Journals (Sweden)

    Nelson Gutiérrez G.

    2015-01-01

    Full Text Available Objective. To develop a Quality Index Method (QIM for gutted and ungutted red tilapia from aquaculture ponds. Materials and methods. 40 specimens of gutted red tilapia and 40 ungutted ones were located in foam polyethylene boxes within layers of ice and storage at 4°C. Three fish were randomly sampled on days 0, 3, 5, 8, 11, 14 and 17 for gutted tilapia, and on days 0, 3, 6, 9, 11, 14 and 16 for ungutted tilapia. A sensorial panel of 8 experts was formed to evaluate the product. With three samples each day with average points of the sensorial attributes proposed in the method, the quality index for gutted and ungutted red tilapia was obtained based on the storage time on ice. Results. The Quality Index Method obtained for gutted and ungutted red tilapia showed maximum values of 21 and 29, respectively. It was adjusted in an increasing lineal model with high correlation between the Quality Index and the storage time on ice. Conclusions. The developed model is useful to determine deterioration levels and to define storage and consumption time. For gutted red tilapia the panel rejected the fish after 8 - 11 days of storage whereas the ungutted red tilapia was rejected after 6 - 9 days.

  9. Use of refractometry and colorimetry as field methods to rapidly assess antimalarial drug quality.

    Science.gov (United States)

    Green, Michael D; Nettey, Henry; Villalva Rojas, Ofelia; Pamanivong, Chansapha; Khounsaknalath, Lamphet; Grande Ortiz, Miguel; Newton, Paul N; Fernández, Facundo M; Vongsack, Latsamy; Manolin, Ot

    2007-01-04

    The proliferation of counterfeit and poor-quality drugs is a major public health problem; especially in developing countries lacking adequate resources to effectively monitor their prevalence. Simple and affordable field methods provide a practical means of rapidly monitoring drug quality in circumstances where more advanced techniques are not available. Therefore, we have evaluated refractometry, colorimetry and a technique combining both processes as simple and accurate field assays to rapidly test the quality of the commonly available antimalarial drugs; artesunate, chloroquine, quinine, and sulfadoxine. Method bias, sensitivity, specificity and accuracy relative to high-performance liquid chromatographic (HPLC) analysis of drugs collected in the Lao PDR were assessed for each technique. The HPLC method for each drug was evaluated in terms of assay variability and accuracy. The accuracy of the combined method ranged from 0.96 to 1.00 for artesunate tablets, chloroquine injectables, quinine capsules, and sulfadoxine tablets while the accuracy was 0.78 for enterically coated chloroquine tablets. These techniques provide a generally accurate, yet simple and affordable means to assess drug quality in resource-poor settings.

  10. Comparison of chemical, electrophoretic and in vitro digestion methods for predicting fish meal nutritive quality

    DEFF Research Database (Denmark)

    Bassompierre, M.; Larsen, K.L.; Zimmermann, W.

    1998-01-01

    Chemical, electrophoretic and in vitro digestion methods were compared with respect to predictions given regarding fish meal (FM) quality. FMs were manufactured by mixing a press-cake, with spray dried stickwater concentrate from the identical raw material, thereby providing samples containing...

  11. Estimation of quality of labour life of personnel: method and possibilities of its application

    OpenAIRE

    Kompaniets, V.

    2009-01-01

    An author offers of principle a new method of estimation of level of quality of labour life of personnel, which takes into account sotsiokulturniy approach. It is based on vision of necessities of man and realization of them in labour from point of christianity, on the basis of which mentality was formed of our peoples, its economic culture.

  12. Tensor-based methods for handling missing data in quality-of-life questionnaires.

    Science.gov (United States)

    Garg, Lalit; Dauwels, Justin; Earnest, Arul; Leong, Khai Pang

    2014-09-01

    A common problem with self-report quality-of-life questionnaires is missing data. Despite enormous care and effort to prevent it, some level of missing data is common and unavoidable. Missing data can have a detrimental impact on the data analysis. In this paper, a novel approach to imputing missing data in quality-of-life questionnaires is proposed, based on matrix and tensor decompositions. In order to illustrate and assess those methods, two datasets are considered: The first dataset contains the responses of 100 patients to a systemic lupus erythematosus-specific quality-of-life questionnaire; the other contains the responses of 43 patients to a rhino-conjunctivitis quality-of-life questionnaire. The two datasets contain almost no missing data, and for testing purposes, data entries are removed at random to have missing completely at random data. Several proportions of missing values are considered, and for each, the imputation error is assessed through k-fold cross validation. We also evaluate different imputation methods for missing at random and missing not at randomdata. The numerical results demonstrate that the proposed tensor factorization-based methods outperform standard methods in terms of root mean square error with at least 4% improvement, while the bias and variance are similar.

  13. Data Quality in the Application of Tailored Calendar Methods in Hard-to-Reach Populations

    NARCIS (Netherlands)

    Navarra, M.Q.; Vaart, van der W.; Niehof, Anke

    2012-01-01

    Abstract A tailored calendar method was used to collect retrospective data from hard-to-reach populations: people with very low levels of income, education and literacy that live in complex societal situations and have low trust in authorities. Recognizing the serious threats to data quality in surv

  14. Evaluation of a Standardized Method of Quality Assurance in Mental Health Records: A Pilot Study

    Science.gov (United States)

    Bradshaw, Kelsey M.; Donohue, Bradley; Fayeghi, Jasmine; Lee, Tiffany; Wilks, Chelsey R.; Ross, Brendon

    2016-01-01

    The widespread adoption of research-supported treatments by mental health providers has facilitated empirical development of quality assurance (QA) methods. Research in this area has focused on QA systems aimed at assuring the integrity of research-supported treatment implementation, while examination of QA systems to assure appropriate…

  15. An Improved Method for High Quality Metagenomics DNA Extraction from Human and Environmental Samples

    DEFF Research Database (Denmark)

    Bag, Satyabrata; Saha, Bipasa; Mehta, Ojasvi

    2016-01-01

    and human origin samples. We introduced a combination of physical, chemical and mechanical lysis methods for proper lysis of microbial inhabitants. The community microbial DNA was precipitated by using salt and organic solvent. Both the quality and quantity of isolated DNA was compared with the existing...... methodologies and the supremacy of our method was confirmed. Maximum recovery of genomic DNA in the absence of substantial amount of impurities made the method convenient for nucleic acid extraction. The nucleic acids obtained using this method are suitable for different downstream applications. This improved...

  16. Developing a Theory of Digitally-Enabled Trial-Based Problem Solving through Simulation Methods: The Case of Direct-Response Marketing

    Science.gov (United States)

    Clark, Joseph Warren

    2012-01-01

    In turbulent business environments, change is rapid, continuous, and unpredictable. Turbulence undermines those adaptive problem solving methods that generate solutions by extrapolating from what worked (or did not work) in the past. To cope with this challenge, organizations utilize trial-based problem solving (TBPS) approaches in which they…

  17. Developing a Theory of Digitally-Enabled Trial-Based Problem Solving through Simulation Methods: The Case of Direct-Response Marketing

    Science.gov (United States)

    Clark, Joseph Warren

    2012-01-01

    In turbulent business environments, change is rapid, continuous, and unpredictable. Turbulence undermines those adaptive problem solving methods that generate solutions by extrapolating from what worked (or did not work) in the past. To cope with this challenge, organizations utilize trial-based problem solving (TBPS) approaches in which they…

  18. Enabling Predictive Simulation and UQ of Complex Multiphysics PDE Systems by the Development of Goal-Oriented Variational Sensitivity Analysis and A Posteriori Error Estimation Methods

    Energy Technology Data Exchange (ETDEWEB)

    Ginting, Victor

    2014-03-15

    it was demonstrated that a posteriori analyses in general and in particular one that uses adjoint methods can accurately and efficiently compute numerical error estimates and sensitivity for critical Quantities of Interest (QoIs) that depend on a large number of parameters. Activities include: analysis and implementation of several time integration techniques for solving system of ODEs as typically obtained from spatial discretization of PDE systems; multirate integration methods for ordinary differential equations; formulation and analysis of an iterative multi-discretization Galerkin finite element method for multi-scale reaction-diffusion equations; investigation of an inexpensive postprocessing technique to estimate the error of finite element solution of the second-order quasi-linear elliptic problems measured in some global metrics; investigation of an application of the residual-based a posteriori error estimates to symmetric interior penalty discontinuous Galerkin method for solving a class of second order quasi-linear elliptic problems; a posteriori analysis of explicit time integrations for system of linear ordinary differential equations; derivation of accurate a posteriori goal oriented error estimates for a user-defined quantity of interest for two classes of first and second order IMEX schemes for advection-diffusion-reaction problems; Postprocessing finite element solution; and A Bayesian Framework for Uncertain Quantification of Porous Media Flows.

  19. Preparation of high-quality poly-Si films by a solid phase crystallizing method

    CERN Document Server

    Yao Ruo He

    2002-01-01

    A solid phase crystallizing method has been developed to grow a Si crystal at temperatures as low as 550 degree C. Using this method, a high-quality thin-film polycrystalline silicon (Poly-Si) was obtained. The largest grain size, examined with X-ray diffraction spectroscopy and scanning electron microscopy images of recrystallized samples, is approximately 1 mu m for substrate temperature at 300 degree C and annealed at 550 degree C for 3 hours

  20. Improvement of the image quality of random phase--free holography using an iterative method

    CERN Document Server

    Shimobaba, Tomoyoshi; Endo, Yutaka; Hirayama, Ryuji; Hiyama, Daisuke; Hasegawa, Satoki; Nagahama, Yuki; Sano, Marie; Oikawa, Minoru; Sugie, Takashige; Ito, Tomoyoshi

    2015-01-01

    Our proposed method of random phase-free holography using virtual convergence light can obtain large reconstructed images exceeding the size of the hologram, without the assistance of random phase. The reconstructed images have low-speckle noise in the amplitude and phase-only holograms (kinoforms); however, in low-resolution holograms, we obtain a degraded image quality compared to the original image. We propose an iterative random phase-free method with virtual convergence light to address this problem.

  1. New methods for quality-testing of calcium carbide; Pruefung von Calciumcarbid. Vereinfachte Bestimmungsmethoden

    Energy Technology Data Exchange (ETDEWEB)

    Koehn, J. [Bundesanstalt fuer Materialpruefung, Berlin (Germany). Abt. 4 ' Chemische Sicherheitstechnik'

    2002-07-01

    The Federal Institute for Materials Research and Testing (BAM) is appointed for quality-testing of calcium carbide in accordance with the DIN 53 992 standard. The methods for defining the yields of acetylene and phosphine described in this standard approximately exist since 50 years. BAM developed more suitable methods for this purpose in the meantime which are designed to be introduced in the next revision of this standard. (orig.)

  2. Nordic Housing Enabler

    DEFF Research Database (Denmark)

    Helle, Tina; Brandt, Åse

    2009-01-01

    Development and reliability testing of the Nordic Housing Enabler – an instrument for accessibility assessment of the physical housing. Tina Helle & Åse Brandt University of Lund, Health Sciences, Faculty of Medicine (SE) and University College Northern Jutland, Occupational Therapy department (DK......). Danish Centre for Assistive Technology. Abstract. For decades, accessibility to the physical housing environment for people with functional limitations has been of interest politically, professionally and for the users. Guidelines and norms on accessible housing design have gradually been developed......, however, the built environment shows serious deficits when it comes to accessibility. This study addresses development of a content valid cross-Nordic version of the Housing Enabler and investigation of inter-rater reliability, when used in occupational therapy practice. The instrument was translated from...

  3. Spatially enabled land administration

    DEFF Research Database (Denmark)

    Enemark, Stig

    2006-01-01

    . In other words: Good governance and sustainable development is not attainable without sound land administration or - more broadly – sound land management. The paper presents a land management vision that incorporates the benefits of ICT enabled land administration functions. The idea is that spatial...... enabling of land administration systems managing tenure, valuation, planning, and development will allow the information generated by these activities to be much more useful. Also, the services available to private and public sectors and to community organisations should commensurably improve. Knowledge...... the communication between administrative systems and also establish more reliable data due to the use the original data instead of copies. In Denmark, such governmental guidelines for a service-oriented ITarchitecture in support of e-government are recently adopted. Finally, the paper presents the role of FIG...

  4. Enabling Wind Power Nationwide

    Energy Technology Data Exchange (ETDEWEB)

    Jose Zayas, Michael Derby, Patrick Gilman and Shreyas Ananthan,

    2015-05-01

    Leveraging this experience, the U.S. Department of Energy’s (DOE’s) Wind and Water Power Technologies Office has evaluated the potential for wind power to generate electricity in all 50 states. This report analyzes and quantifies the geographic expansion that could be enabled by accessing higher above ground heights for wind turbines and considers the means by which this new potential could be responsibly developed.

  5. Enabling Global Collaboration

    DEFF Research Database (Denmark)

    Brix, Anders; de Gier, Nicolai

    2014-01-01

    recognizing the value of incremental refinement of tradition and sustainability obtained through cultivation of the culturally and visually sustainable. As a contribution to this development, we propose: 1) The notion of tectonics as a core concept enabling a mutual, cross-cultural design discourse...... of the studio informed by the theory of tectonics together provides cross-cultural students with a mutual language to discuss intrinsic matters of form....

  6. Meta-QC-Chain: comprehensive and fast quality control method for metagenomic data.

    Science.gov (United States)

    Zhou, Qian; Su, Xiaoquan; Jing, Gongchao; Ning, Kang

    2014-02-01

    Next-generation sequencing (NGS) technology has revolutionized and significantly impacted metagenomic research. However, the NGS data usually contains sequencing artifacts such as low-quality reads and contaminating reads, which will significantly compromise downstream analysis. Many quality control (QC) tools have been proposed, however, few of them have been verified to be suitable or efficient for metagenomic data, which are composed of multiple genomes and are more complex than other kinds of NGS data. Here we present a metagenomic data QC method named Meta-QC-Chain. Meta-QC-Chain combines multiple QC functions: technical tests describe input data status and identify potential errors, quality trimming filters poor sequencing-quality bases and reads, and contamination screening identifies higher eukaryotic species, which are considered as contamination for metagenomic data. Most computing processes are optimized based on parallel programming. Testing on an 8-GB real dataset showed that Meta-QC-Chain trimmed low sequencing-quality reads and contaminating reads, and the whole quality control procedure was completed within 20 min. Therefore, Meta-QC-Chain provides a comprehensive, useful and high-performance QC tool for metagenomic data. Meta-QC-Chain is publicly available for free at: http://computationalbioenergy.org/meta-qc-chain.html.

  7. A METHOD FOR QUALITY POWER PROVIDER TO OPERATE IN DISTORTED SUPPLY CONDITION

    Directory of Open Access Journals (Sweden)

    K.CHANDRASEKARAN

    2011-08-01

    Full Text Available Power Quality is a major concern within power industry and consumers. Poor quality of supply will affect the performance of customer equipment such as computers, microprocessors, adjustable speed drives, power electronic controllers, life saving equipment in hospitals, etc. and result in heavy financial losses to customers due to loss of production or breakdown in industries or loss of life in a hospital. The two major power quality disturbances are voltage sag and harmonic distortion. In this paper, a Quality Power Provider (QPP based on voltage source inverter is modeled by simulation to compensate the power quality disturbances such as voltage sag and voltage harmonics in the distorted supply condition. The phase locked loop (PLL is an important control unit of the QPP control scheme. To obtain accurate phase information and frequency of the input supply, the dqPLL method has been proposed. Simulation results based on MATLAB and PSCAD software are presented to verify the performance of the proposed QPP. QPP has improved the quality of power supply at the sensitive load end.

  8. Quality Evaluation of Potentilla fruticosa L. by High Performance Liquid Chromatography Fingerprinting Associated with Chemometric Methods

    Science.gov (United States)

    Liu, Wei; Wang, Dongmei; Liu, Jianjun; Li, Dengwu; Yin, Dongxue

    2016-01-01

    The present study was performed to assess the quality of Potentilla fruticosa L. sampled from distinct regions of China using high performance liquid chromatography (HPLC) fingerprinting coupled with a suite of chemometric methods. For this quantitative analysis, the main active phytochemical compositions and the antioxidant activity in P. fruticosa were also investigated. Considering the high percentages and antioxidant activities of phytochemicals, P. fruticosa samples from Kangding, Sichuan were selected as the most valuable raw materials. Similarity analysis (SA) of HPLC fingerprints, hierarchical cluster analysis (HCA), principle component analysis (PCA), and discriminant analysis (DA) were further employed to provide accurate classification and quality estimates of P. fruticosa. Two principal components (PCs) were collected by PCA. PC1 separated samples from Kangding, Sichuan, capturing 57.64% of the variance, whereas PC2 contributed to further separation, capturing 18.97% of the variance. Two kinds of discriminant functions with a 100% discrimination ratio were constructed. The results strongly supported the conclusion that the eight samples from different regions were clustered into three major groups, corresponding with their morphological classification, for which HPLC analysis confirmed the considerable variation in phytochemical compositions and that P. fruticosa samples from Kangding, Sichuan were of high quality. The results of SA, HCA, PCA, and DA were in agreement and performed well for the quality assessment of P. fruticosa. Consequently, HPLC fingerprinting coupled with chemometric techniques provides a highly flexible and reliable method for the quality evaluation of traditional Chinese medicines. PMID:26890416

  9. Digital image quality measurements by objective and subjective methods from series of parametrically degraded images

    Science.gov (United States)

    Tachó, Aura; Mitjà, Carles; Martínez, Bea; Escofet, Jaume; Ralló, Miquel

    2013-11-01

    Many digital image applications like digitization of cultural heritage for preservation purposes operate with compressed files in one or more image observing steps. For this kind of applications JPEG compression is one of the most widely used. Compression level, final file size and quality loss are parameters that must be managed optimally. Although this loss can be monitored by means of objective image quality measurements, the real challenge is to know how it can be related with the perceived image quality by observers. A pictorial image has been degraded by two different procedures. The first, applying different levels of low pass filtering by convolving the image with progressively broad Gauss kernels. The second, saving the original file to a series of JPEG compression levels. In both cases, the objective image quality measurement is done by analysis of the image power spectrum. In order to obtain a measure of the perceived image quality, both series of degraded images are displayed on a computer screen organized in random pairs. The observers are compelled to choose the best image of each pair. Finally, a ranking is established applying Thurstone scaling method. Results obtained by both measurements are compared between them and with other objective measurement method as the Slanted Edge Test.

  10. Quality Evaluation of Potentilla fruticosa L. by High Performance Liquid Chromatography Fingerprinting Associated with Chemometric Methods.

    Directory of Open Access Journals (Sweden)

    Wei Liu

    Full Text Available The present study was performed to assess the quality of Potentilla fruticosa L. sampled from distinct regions of China using high performance liquid chromatography (HPLC fingerprinting coupled with a suite of chemometric methods. For this quantitative analysis, the main active phytochemical compositions and the antioxidant activity in P. fruticosa were also investigated. Considering the high percentages and antioxidant activities of phytochemicals, P. fruticosa samples from Kangding, Sichuan were selected as the most valuable raw materials. Similarity analysis (SA of HPLC fingerprints, hierarchical cluster analysis (HCA, principle component analysis (PCA, and discriminant analysis (DA were further employed to provide accurate classification and quality estimates of P. fruticosa. Two principal components (PCs were collected by PCA. PC1 separated samples from Kangding, Sichuan, capturing 57.64% of the variance, whereas PC2 contributed to further separation, capturing 18.97% of the variance. Two kinds of discriminant functions with a 100% discrimination ratio were constructed. The results strongly supported the conclusion that the eight samples from different regions were clustered into three major groups, corresponding with their morphological classification, for which HPLC analysis confirmed the considerable variation in phytochemical compositions and that P. fruticosa samples from Kangding, Sichuan were of high quality. The results of SA, HCA, PCA, and DA were in agreement and performed well for the quality assessment of P. fruticosa. Consequently, HPLC fingerprinting coupled with chemometric techniques provides a highly flexible and reliable method for the quality evaluation of traditional Chinese medicines.

  11. A New Quality Control Method base on IRMCD for Wind Profiler Observation towards Future Assimilation Application

    Science.gov (United States)

    Chen, Min; Zhang, Yu

    2017-04-01

    A wind profiler network with a total of 65 profiling radars was operated by the MOC/CMA in China until July 2015. In this study, a quality control procedure is constructed to incorporate the profiler data from the wind-profiling network into the local data assimilation and forecasting system (BJRUC). The procedure applies a blacklisting check that removes stations with gross errors and an outlier check that rejects data with large deviations from the background. Instead of the bi-weighting method, which has been commonly implemented in outlier elimination for one-dimensional scalar observations, an outlier elimination method is developed based on the iterated reweighted minimum covariance determinant (IRMCD) for multi-variate observations such as wind profiler data. A quality control experiment is separately performed for subsets containing profiler data tagged in parallel with/without rain flags at every 00UTC/12UTC from 20 June to 30 Sep 2015. From the results, we find that with the quality control, the frequency distributions of the differences between the observations and model background become more Gaussian-like and meet the requirements of a Gaussian distribution for data assimilation. Further intensive assessment for each quality control step reveals that the stations rejected by blacklisting contain poor data quality, and the IRMCD rejects outliers in a robust and physically reasonable manner.

  12. Mixed-methods research in pharmacy practice: recommendations for quality reporting. Part 2.

    Science.gov (United States)

    Hadi, Muhammad Abdul; Alldred, David Phillip; Closs, S José; Briggs, Michelle

    2014-02-01

    This is the second of two papers that explore the use of mixed-methods research in pharmacy practice. This paper discusses the rationale, applications, limitations and challenges of conducting mixed-methods research. As with other research methods, the choice of mixed-methods should always be justified because not all research questions require a mixed-methods approach. Mixed-methods research is particularly suitable when one dataset may be inadequate in answering the research question, an explanation of initial results is required, generalizability of qualitative findings is desired or broader and deeper understanding of a research problem is necessary. Mixed-methods research has its own challenges and limitations, which should be considered carefully while designing the study. There is a need to improve the quality of reporting of mixed-methods research. A framework for reporting mixed-methods research is proposed, for researchers and reviewers, with the intention of improving its quality. Pharmacy practice research can benefit from research that uses both 'numbers' (quantitative) and 'words' (qualitative) to develop a strong evidence base to support pharmacy-led services. © 2013 Royal Pharmaceutical Society.

  13. [Evaluating comprehensive quality of sediment in Dianchi Lake using adjusted AHP method and 137Cs dating].

    Science.gov (United States)

    Zhang, Yan; Deng, Xi-Hai; Peng, Bu-Zhuo

    2006-08-01

    It is difficult to evaluate comprehensive quality of sediment and to understand development trend of pollution because of absence of monitoring data, especially history data. Combining the method of 137Cs dating with the ways of general sampling and measurement can easily resolve the problem of absence of data and also provide the possibility for calculating weighted environmental quality comprehensive index using the adjusted analytical hierarchy process (AHP) method. In order to overcome the willfulness the judgment matrix is formed objectively based on calculating monitoring data. Based on the monitoring data of sediment pollution and the weights of various factors gained by adjusted AHP method the comprehensive quality of sediment in each zone of Dianchi Lake was evaluated and the results indicated that the pollution of sediments in each zone at the present be serious more than that in the history. The condition may be related to the industrial development and distribution of industries in Dianchi Lake basin. Therefore, in order to improve the comprehensive quality of sediment in Dianchi Lake and to prevent the secondary pollution of heavy metals in sediment from happening, it is necessary to control the pollutants discharge and to remove the pollutants with various ways.

  14. Quality evaluation of energy consumed in flow regulation method by speed variation in centrifugal pumps

    Science.gov (United States)

    Morales, S.; Culman, M.; Acevedo, C.; Rey, C.

    2014-06-01

    Nowadays, energy efficiency and the Electric Power Quality are two inseparable issues in the evaluation of three-phase induction motors, framed within the program of Rational and Efficient Use of Energy (RUE).The use of efficient energy saving devices has been increasing significantly in RUE programs, for example the use of variable frequency drives (VFD) in pumping systems.The overall objective of the project was to evaluate the impact on power quality and energy efficiency in a centrifugal pump driven by an induction three-phase motor, using the flow control method of speed variation by VFD. The fundamental purpose was to test the opinions continuously heard about the use of flow control methods in centrifugal pumps, analyzing the advantages and disadvantages that have been formulated deliberately in order to offer support to the industry in taking correct decisions. The VFD changes the speed of the motor-pump system increasing efficiency compared to the classical methods of regulation. However, the VFD originates conditions that degrade the quality of the electric power supplied to the system and therefore its efficiency, due to the nonlinearity and presence of harmonic currents. It was possible to analyze the power quality, ensuring that the information that comes to the industry is generally biased.

  15. An electrical test method for quality detecting of wafer level eutectic bonding

    Science.gov (United States)

    Zhang, Lemin; Jiao, Binbin; Ku, Will; Tseng, Li-Tien; Kong, Yanmei; Chien, Yu-Hao; Yun, Shichang; Chen, Dapeng

    2017-01-01

    As the costs of packaging and testing account for a substantial portion of microelectromechanical system (MEMS) devices, an effective and convenient characterization method is urgent to be investigated to lower the cost. In this paper, an electrical test method was utilized, and the test key used for a four-probe current-voltage test was designed to monitor the quality of the AuSn eutectic bonding. The electrical test can directly detect whether or not voids existed in the bonding layer. The difference in alloy state, for example, the existence of the (Au, Ni) 3Sn2 phase confirmed by the scanning electron microscope and energy dispersive x-ray spectroscopy test, can also be reflected by resistivity variation. The electrical test can be implemented automatically and conveniently unlike other characterization methods. Therefore, it is suitable to be applied in quality inspection in industrial production.

  16. A review on tomato authenticity: quality control methods in conjunction with multivariate analysis (chemometrics).

    Science.gov (United States)

    Arvanitoyannis, Ioannis S; Vaitsi, Olga B

    2007-01-01

    Authenticity and traceability have been two of the most important issues in the food chain. Authenticity in particular, is closely related with both food quality and safety issues. Vegetables stand for a category of foods heavily affected by adulteration either in terms of geographic origin (national or international level) or production methods (organic or conventional production, fertilizers, pesticides, genetically modified vegetables). This review aims at addressing most of the currently applied methods for ensuring quality control of vegetables; a) instrumental: ion chromatography, high pressure liquid chromatography, atomic absorption spectrophotometry, electronic nose and mass spectroscopy and b) sensory analysis. The results of all the above mentioned methods were analyzed by means of multivariate analysis (principal component analysis, discriminant analysis, cluster analysis, canonical analysis, and factor analysis). All ensuing results and conclusions are summarized in eight comprehensive tables.

  17. An Evaluation of Two Hydrograph Separation Methods of Potential Use in Regional Water Quality Assessment

    Energy Technology Data Exchange (ETDEWEB)

    Huff, D.D.

    1999-01-01

    Streamflow data are more useful for evaluating hydrologic model results and studying water quality once baseflow and storm runoff have been separated. However, it is important to select an appropriate hydrograph separation method. They examined tow methods and evaluated their conceptual basis, ease of application, cost of data processing, and acceptability of results. they chose the quick flow hydrograph separation method, which is in use at the Coweeta Hydrologic Laboratory, because it gives acceptable results and is easy and inexpensive to use. For regional assessment, they anticipate that the Coweeta program will be useful as an aid in developing general quantitative relationships between changes in land use and the associated changes in surface runoff yield and water quality degradation.

  18. The Poka-Yoke method as an improving quality tool of operations in the process

    Directory of Open Access Journals (Sweden)

    M. Dudek-Burlikowska

    2009-09-01

    Full Text Available Purpose: A new approach for the implementation of quality philosophy Zero Quality Defects with usage of the Poka-Yoke method in the polish organization has been presented.Design/methodology/approach: The possibility of usage of mistake proofing device is connected with monitoring and improvement of operations in the process.Findings: At the present time the organizations should implement quality tools, techniques, methods which support the prevention strategy and should pay attention to improving each element and operations in the process.Research limitations/implications: Generally activity aim at prevent defects has been described. The Poka-Yoke method of preventing errors by putting limits on how operation can be performed in order to force the correct completion of the operation has been presented.Practical implications: The possibility of implementing of the Poka-Yoke method as a factor of improving operation in the process in the motorizations companies has been shown.Originality/value:value The aim of method Poka-Yoke in those practical examples is to eliminated or minimize human error in manufacturing process and management as a result of mental and physical human imperfections. The graphical proposal: connection the PDCA cycle with the Poka-Yoke has been created.

  19. Designing Excellence and Quality Model for Training Centers of Primary Health Care: A Delphi Method Study

    Directory of Open Access Journals (Sweden)

    Jafar-Sadegh TABRIZI

    2015-10-01

    Full Text Available Background: Excellence and quality models are comprehensive methods for improving the quality of healthcare. The aim of this study was to design excellence and quality model for training centers of primary health care using Delphi method. Methods: In this study, Delphi method was used. First, comprehensive information were collected using literature review. In extracted references, 39 models were identified from 34 countries and related sub-criteria and standards were extracted from 34 models (from primary 39 models. Then primary pattern including 8 criteria, 55 sub-criteria, and 236 standards was developed as a Delphi questionnaire and evaluated in four stages by 9 specialists of health care system in Tabriz and 50 specialists from all around the country.Results: Designed primary model (8 criteria, 55 sub-criteria, and 236 standards were concluded with 8 criteria, 45 sub-criteria, and 192 standards after 4 stages of evaluations by specialists. Major criteria of the model are leadership, strategic and operational planning, resource management, information analysis, human resources management, process management, costumer results, and functional results, where the top score was assigned as 1000 by specialists. Functional results had the maximum score of 195 whereas planning had the minimum score of 60. Furthermore the most and the least sub-criteria was for leadership with 10 sub-criteria and strategic planning with 3 sub-criteria, respectively. Conclusion: The model that introduced in this research has been designed following 34 reference models of the world. This model could provide a proper frame for managers of health system in improving quality. Keywords: Quality model, Excellence model, Training centers, Primary cares, Iran

  20. [Research on Assessment Methods of Spectrum Data Quality of Core Scan].

    Science.gov (United States)

    Xiu, Lian-cun; Zheng, Zhi-zhong; Yin, Liang; Chen, Chun-xia; Yu, Zheng-kui; Huang, Bin; Zhang, Qiu-ning; Xiu, Xiao-xu; Gao, Yang

    2015-08-01

    Core scan is the instrument used for core spectrum and pictures detection that has been developed in recent years. Cores' data can be digitized with this equipment, then automatic core catalog can be achieved, which provides basis for geological research, mineral deposit study and peripheral deposit prospecting. Meanwhile, an online database of cores can be established by the means of core digitalization to solve the cost problem caused by core preservation and share resources. Quality of core data measurement directly affects the mineral identification, reliability of parameter inversion results. Therefore it's very important to quasi-manage the assessment of data quality with the instrument before cores' spectrum testing services. Combined with the independent R&D of CSD350A type core scan, and on the basis of spectroscopy basic theory, spectrum analysis methods, core spectrum analysis requirements, key issues such as data quality assessment methods, evaluation criteria and target parameters has been discussed in depth, and comprehensive assessment of independent R&D of core scan has been conducted, which indicates the reliability and validity of spectrum measurements of the instrument. Experimental tests show that the methods including test parameters and items can perfectly response the measurements of reflectance spectrum, wavelength accuracy, repeatability and signal to noise ratio with the instrument. Thus the quality of core scan data can be evaluated correctly, and the foundation of data quality for commercial services can be provided. In the case of the current lack of relevant assessment criteria, the method this study proposes for the assessment has great value in the work of core spectrum measurements.

  1. Control of cheese quality – strategies and methods for delivery of consistent sensory product quality at the point of consumption

    OpenAIRE

    Kraggerud, Hilde

    2011-01-01

    An effective approach to quality control is an important issue for a food producer, as consumers expect consistent delivery of products. Two important strategies for control of food product end quality was discussed in this thesis: Process regulation and Statistical Process control (SPC). Extensive experiments were carried out in order to demonstrate different aspects of control of cheese quality. The sensory quality of a product is of great importance, as it is directly perceived at consu...

  2. Power quality improvement of single-phase photovoltaic systems through a robust synchronization method

    DEFF Research Database (Denmark)

    Hadjidemetriou, Lenos; Kyriakides, Elias; Yang, Yongheng;

    2014-01-01

    An increasing amount of single-phase photovoltaic (PV) systems on the distribution network requires more advanced synchronization methods in order to meet the grid codes with respect to power quality and fault ride through capability. The response of the synchronization technique selected...... is crucial for the performance of PV inverters. In this paper, a new synchronization method with good dynamics and accurate response under highly distorted voltage is proposed. This method uses a Multi-Harmonic Decoupling Cell (MHDC), which cancels out the oscillations on the synchronization signals due...

  3. Exploring simple assessment methods for lighting quality with architecture and design students

    DEFF Research Database (Denmark)

    Madsen, Merete

    2006-01-01

    Architecture and design students are frequently required to establish suitable lighting conditions for the buildings and spaces they design as part of their studio courses. While lighting design guidelines are avaiilable, students find out quickly, that lighting quality is a complex issue...... that cannot be assessed by simple equations or rules-of-thumb. Balancing the many an often contradictory aspects of energy efficiency and high quality lighting design is a complex undertaking not just for students. The work described in this paper is one result of an academic staff exchange between...... the Schools of Architecture in Copenhagen and Victoria University of Wellington (New Zealand). The authors explore two approaches to teaching students simple assessment methods that can contribute to making more informed decisions about the luminous environment and its quality. One approach deals...

  4. Statistical methods for quality assurance basics, measurement, control, capability, and improvement

    CERN Document Server

    Vardeman, Stephen B

    2016-01-01

    This undergraduate statistical quality assurance textbook clearly shows with real projects, cases and data sets how statistical quality control tools are used in practice. Among the topics covered is a practical evaluation of measurement effectiveness for both continuous and discrete data. Gauge Reproducibility and Repeatability methodology (including confidence intervals for Repeatability, Reproducibility and the Gauge Capability Ratio) is thoroughly developed. Process capability indices and corresponding confidence intervals are also explained. In addition to process monitoring techniques, experimental design and analysis for process improvement are carefully presented. Factorial and Fractional Factorial arrangements of treatments and Response Surface methods are covered. Integrated throughout the book are rich sets of examples and problems that help readers gain a better understanding of where and how to apply statistical quality control tools. These large and realistic problem sets in combination with the...

  5. Three-Dimensional Water-Quality Simulation for River Based on VOF Method

    Institute of Scientific and Technical Information of China (English)

    敖雪菲; 王晓玲; 宋明瑞; 邓韶辉; 李松敏

    2016-01-01

    In the present study, considering the transport and transformation processes of variables, a three-dimensional water quality model for the river system was established, which coupled the volume of fluid(VOF) method with thek-ε turbulence mathematical model. Then, the water hydrodynamic characteristics and transport processes for BOD5, NH3-N and TP were analyzed. The results showed that the water surface of convex bank was a little lower than that of concave bank due to the centrifugal force near the bend, and most concentrations were infe-rior to the typeⅤ standard indexes of surface water environmental quality. The model validation indicated that the errors between the simulated and monitored values were comparatively small, satisfying the application demands and providing scientific basis and decision support for the restoration and protection of water quality.

  6. Enabling Digital Literacy

    DEFF Research Database (Denmark)

    Ryberg, Thomas; Georgsen, Marianne

    2010-01-01

    There are some tensions between high-level policy definitions of “digital literacy” and actual teaching practice. We need to find workable definitions of digital literacy; obtain a better understanding of what digital literacy might look like in practice; and identify pedagogical approaches, which......, these operate on a meso-level mediating between high-level concepts of digital literacy and classroom practice....... support teachers in designing digital literacy learning. We suggest that frameworks such as Problem Based Learning (PBL) are approaches that enable digital literacy learning because they provide good settings for engaging with digital literacy. We illustrate this through analysis of a case. Furthermore...

  7. A method of detecting contamination events using multiple conventional water quality sensors.

    Science.gov (United States)

    Liu, Shuming; Che, Han; Smith, Kate; Chen, Chao

    2015-01-01

    Early warning systems are often used for detecting contamination accidents. Traditional event detection methods suffer from high false negative and false positive errors. This paper proposes a detection method using multiple conventional water quality sensors and introduces a method to determine the values of parameters, which was configured as a multiple optimization problem and solved using a non-dominated sorting genetic algorithm (NSGA-II). The capability of the proposed method to detect contamination events caused by cadmium nitrate is demonstrated in this paper. The performance of the proposed method to detect events caused by different concentrations was also investigated. Results show that, after calibration, the proposed method can detect a contamination event 1 min after addition of cadmium nitrate at the concentration of 0.008 mg/l and has low false negative and positive rates.

  8. Robust Technique for Measuring and Simulating Silicon Wafer Quality Characteristics that Enable the Prediction of Solar Cell Electrical Performance of MEMC Silicon Wafer. Cooperative Research and Development Final Report, CRADA Number CRD-11-438

    Energy Technology Data Exchange (ETDEWEB)

    Sopori, Bhushan [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2015-12-01

    NREL and MEMC Electronic Materials are interested in developing a robust technique for monitoring material quality of mc-Si and mono-Si wafers -- a technique that can provide relevant data to accurately predict the performance of solar cells fabricated on them. Previous work, performed under two TSAs between NREL and MEMC, has established that dislocation clusters are the dominant performance-limiting factor in MEMC mc-Si solar cells. The work under this CRADA will go further in verifying these results on a larger data set, evaluate possibilities of faster method(s) for mapping dislocations in wafers/ingots, understanding dislocation generation during ingot casting, and helping MEMC to have an internal capability for basic characterization that will provide feedback needed for more accurate crystallization simulations. NREL has already developed dislocation mapping technique and developed a basic electronic model (called Network Model) that uses spatial distribution of dislocations to predict the cell performance. In this CRADA work, we will use these techniques to: (i) establish dislocation, grain size, and grain orientation distributions of the entire ingots (through appropriate DOE) and compare these with theoretical models developed by MEMC, (ii) determine concentrations of some relevant impurities in selected wafers, (iii) evaluate potential of using photoluminescence for dislocation mapping and identification of recombination centers, (iv) evaluate use of diode array analysis as a detailed characterization tool, and (v) establish dislocation mapping as a wafer-quality monitoring tool for commercial mc-Si production.

  9. Solvent and extraction methods effects on the quality of eel (Anguilla bicolor) oil

    Science.gov (United States)

    Sasongko, H.; Efendi, N. R.; Budihardjo, A.; Farida, Y.; Amartiwi, T.; Rahmawati, A. A.; Wicaksono, A.; Sugiyarto

    2017-01-01

    Eel (Anguilla bicolor) is a general fish consumption in many countries, especially Japan, China, Germany, and France. Besides its vitamin rich, eel oil is also known to contain fatty acids that are necessary for pharmaceutical purposes and as food a supplement. This research was aimed to evaluate the quality of eel oil by different solvent and extraction methods. In this study, fresh eels were extracted using maceration and reflux methods.Chloroform was used as the solvent in the maceration while water used in the reflux method. The oil quality was examined based on the Official Methods of Analysis of the Association of Official Analytical Chemist (AOAC).The result showed that the yield of eel oil using maceration method was 5.44% ± 0.64 with a specific gravity of 0.915 g/mL, while reflux method obtained the yield of 5.33 % ± 0.84 and specific gravity of 0.8575 g/mL. The physicochemical parameters of oil quality used in this study were acid, peroxide, saponification, and iodine value. The maceration method obtained the acid value of 17.389 mgKOH/g, the peroxide value of 7.021meqO2/kg, the saponification value of 111.16mgKOH/g, and the iodine value of 65.14 WIJS. While the reflux method produced the acid value of 9.116 mgKOH/g, the peroxide value of 6.088 meqO2/kg, the saponification value of 70 mgKOH/g, and the iodine value of 87.74 WIJS.

  10. Extensive Peptide Fractionation and y1 Ion-Based Interference Detection Method for Enabling Accurate Quantification by Isobaric Labeling and Mass Spectrometry.

    Science.gov (United States)

    Niu, Mingming; Cho, Ji-Hoon; Kodali, Kiran; Pagala, Vishwajeeth; High, Anthony A; Wang, Hong; Wu, Zhiping; Li, Yuxin; Bi, Wenjian; Zhang, Hui; Wang, Xusheng; Zou, Wei; Peng, Junmin

    2017-02-22

    Isobaric labeling quantification by mass spectrometry (MS) has emerged as a powerful technology for multiplexed large-scale protein profiling, but measurement accuracy in complex mixtures is confounded by the interference from coisolated ions, resulting in ratio compression. Here we report that the ratio compression can be essentially resolved by the combination of pre-MS peptide fractionation, MS2-based interference detection, and post-MS computational interference correction. To recapitulate the complexity of biological samples, we pooled tandem mass tag (TMT)-labeled Escherichia coli peptides at 1:3:10 ratios and added in ∼20-fold more rat peptides as background, followed by the analysis of two-dimensional liquid chromatography (LC)-MS/MS. Systematic investigation shows that quantitative interference was impacted by LC fractionation depth, MS isolation window, and peptide loading amount. Exhaustive fractionation (320 × 4 h) can nearly eliminate the interference and achieve results comparable to the MS3-based method. Importantly, the interference in MS2 scans can be estimated by the intensity of contaminated y1 product ions, and we thus developed an algorithm to correct reporter ion ratios of tryptic peptides. Our data indicate that intermediate fractionation (40 × 2 h) and y1 ion-based correction allow accurate and deep TMT profiling of more than 10 000 proteins, which represents a straightforward and affordable strategy in isobaric labeling proteomics.

  11. [Evaluation of urban human settlement quality in Ningxia based on AHP and the entropy method].

    Science.gov (United States)

    Li, Shuai; Wei, Hong; Ni, Xi-Lu; Gu, Yan-Wen; Li, Chang-Xiao

    2014-09-01

    As one of the key indicators of the urbanization and the sustainable development of cities, urban human settlement quality has been a hot issue. In this paper, an evaluation system containing indicators related to four aspects (ecological, social, humanities and economic environments) was established to assess the urban human settlement quality in five main cities in Ningxia Hui Autonomous Region, Northwest China. After calculating each indicator' s weight in the evaluation system through AHP and the entropy method, the quality of urban human settlement was analyzed. Results showed that Yinchuan had a score of 0. 85 for the quality of human settlement, Shizuishan 0.62, Wuzhong 0.43, Zhongwei 0.33, and Guyuan 0.32, respectively. Shizuishan got the highest score in the eco-environment aspect, and Yinchuan had the highest scores for social, humanities and economic environments. Zhongwei and Guyuan had relatively low scores in all the four urban human settlement aspects. Coordination analysis showed that internal coordination was moderate for Yinchuan (0.79) and Shizuishan (0.72), and relatively good for the other cities. However, coordination was relatively poor among the five cities, especially in social environment (0.48). These results suggested that an unsatisfied situation existed in terms of the urban human settlement quality in Ningxia, and that corresponding measures should be taken to accelerate the development of vulnerable indicators, so as to coordinate all the urban human settlement aspects within and among cities.

  12. Effect of different tumbling marination methods and time on the quality characteristics of prepared pork chops

    Directory of Open Access Journals (Sweden)

    Tian Gao

    2015-09-01

    Full Text Available AbstractThe combined effects of tumbling marination methods (Vacuum continuous tumbling marination, CT; Vacuum intermittent tumbling marination, IT and effective tumbling time (4, 6, 8 and 10 h on quality characteristics of prepared boneless pork chops were investigated. The results showed that regardless of tumbling time, CT method significantly increased the pH, product yield, cohesiveness, resilience, sensory tenderness and overall flavor (p<0.05 compared with IT method, and CT method also significantly decreased the pressing loss, cooking loss, shear force value (SFV, hardness and chewiness (p<0.05 compared with IT method. With the effective tumbling time increasing from 4 h to 10 h, the product yield and sensory attributes of prepared pork chops increased at first and then decreased, whereas the pressing loss, cooking loss, SFV, hardness and chewiness decreased at first and then increased. Additionally, an interaction between CT method and effective tumbling time was also observed. These results suggested that CT method of 8 h obtained the best quality characteristics of prepared pork chops, which should be adopted.

  13. New Power Quality Analysis Method Based on Chaos Synchronization and Extension Neural Network

    Directory of Open Access Journals (Sweden)

    Meng-Hui Wang

    2014-10-01

    Full Text Available A hybrid method comprising a chaos synchronization (CS-based detection scheme and an Extension Neural Network (ENN classification algorithm is proposed for power quality monitoring and analysis. The new method can detect minor changes in signals of the power systems. Likewise, prominent characteristics of system signal disturbance can be extracted by this technique. In the proposed approach, the CS-based detection method is used to extract three fundamental characteristics of the power system signal and an ENN-based clustering scheme is then applied to detect the state of the signal, i.e., normal, voltage sag, voltage swell, interruption or harmonics. The validity of the proposed method is demonstrated by means of simulations given the use of three different chaotic systems, namely Lorenz, New Lorenz and Sprott. The simulation results show that the proposed method achieves a high detection accuracy irrespective of the chaotic system used or the presence of noise. The proposed method not only achieves higher detection accuracy than existing methods, but also has low computational cost, an improved robustness toward noise, and improved scalability. As a result, it provides an ideal solution for the future development of hand-held power quality analyzers and real-time detection devices.

  14. Molecular methods for microbiological quality control of meat and meat products: a review.

    Science.gov (United States)

    Gokulakrishnan, P; Vergis, Jess

    2015-01-01

    Achieving food safety is a global health goal and the food-borne diseases take a major check on global health. Therefore, detection of microbial pathogens in food is the solution to the prevention and recognition of problems related to health and safety. Conventional and standard bacterial detection methods such as culture and colony counting methods and immunology-based methods may take up to several hours or even a few days to yield a result. Obviously, this is inadequate, and recently many researchers are focusing towards the progress of rapid diagnostic methods. The advent of molecular techniques has led to the development of a diverse array of assay for quality control of meat and meat products. Rapid analysis using DNA hybridization and amplification techniques offer more sensitivity and specificity to get results than culture based methods as well as dramatic reduction in the time to get results. Many methods have also achieved the high level automation, facilitating their application as routine sample screening assays. This review is intended to provide an overview of the molecular methods for microbiological quality control of meat and meat products.

  15. Fast analysis of glibenclamide and its impurities: quality by design framework in capillary electrophoresis method development.

    Science.gov (United States)

    Furlanetto, Sandra; Orlandini, Serena; Pasquini, Benedetta; Caprini, Claudia; Mura, Paola; Pinzauti, Sergio

    2015-10-01

    A fast capillary zone electrophoresis method for the simultaneous analysis of glibenclamide and its impurities (I(A) and I(B)) in pharmaceutical dosage forms was fully developed within a quality by design framework. Critical quality attributes were represented by I(A) peak efficiency, critical resolution between glibenclamide and I(B), and analysis time. Experimental design was efficiently used for rapid and systematic method optimization. A 3(5)//16 symmetric screening matrix was chosen for investigation of the five selected critical process parameters throughout the knowledge space, and the results obtained were the basis for the planning of the subsequent response surface study. A Box-Behnken design for three factors allowed the contour plots to be drawn and the design space to be identified by introduction of the concept of probability. The design space corresponded to the multidimensional region where all the critical quality attributes reached the desired values with a degree of probability π ≥ 90%. Under the selected working conditions, the full separation of the analytes was obtained in less than 2 min. A full factorial design simultaneously allowed the design space to be validated and method robustness to be tested. A control strategy was finally implemented by means of a system suitability test. The method was fully validated and was applied to real samples of glibenclamide tablets.

  16. Effects of Different Regulatory Methods on Improvement of Greenhouse Saline Soils, Tomato Quality, and Yield

    Directory of Open Access Journals (Sweden)

    Hou Maomao

    2014-01-01

    Full Text Available To identify effective regulatory methods scheduling with the compromise between the soil desalination and the improvement of tomato quality and yield, a 3-year field experiment was conducted to evaluate and compare the effect of straw mulching and soil structure conditioner and water-retaining agent on greenhouse saline soils, tomato quality, and yield. A higher salt removing rate of 80.72% in plough layer with straw mulching was obtained based on the observation of salt mass fraction in 0~20 cm soil layer before and after the experiment. Salts were also found to move gradually to the deeper soil layer with time. Straw mulching enhanced the content of soil organic matter significantly and was conductive to reserve soil available N, P, and K, while available P and K in soils of plough layer with soil structure conditioner decreased obviously; thus a greater usage of P fertilizer and K fertilizer was needed when applying soil structure conditioner. Considering the evaluation indexes including tomato quality, yield, and desalination effects of different regulatory methods, straw mulching was recommended as the main regulatory method to improve greenhouse saline soils in south China. Soil structure conditioner was the suboptimal method, which could be applied in concert with straw mulching.

  17. Impact of Cantienica® Method to Improve Urinary Incontinence and Quality of Life

    Directory of Open Access Journals (Sweden)

    Adriana Repková

    2016-03-01

    Full Text Available Background: The aim of this study was to determine the impact of symptoms of urinary incontinence by individuals, with the help of pelvic floor muscle's activation using Cantienica® and the subsequent effect on the quality of women's life. Patients and methods: The selected sample consists of two groups - experimental and control. The experimental group consisted of 31 female patients with incontinence, who completed therapeutic exercises using features of Cantienica® method. Control group consisted of 31 female patients with incontinence, which had taken a different way of conservative therapy. Results: The research has found that in the group of female patients who completed the therapeutic exercise by Benita Cantieni method, came in both phases to significantly greater change in the quality of life and greater alleviation of incontinence among the women who completed the other conservative treatments of incontinence. Conclusion: It can be alleged by the observed results, that the evaluated method has an effect on improving the quality of life and alleviating the symptoms of urinary incontinence in women.

  18. Enabling the Disabled

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    China tries to improve the quality of life for disabled people Based on achievements during the past five years, people with disabilities in China will have greater access to education and employment during the 12th Five-Year Plan period (2011-15), said Wang Naikun, Executive Vice President of the China Disabled Persons’ Federation (CDPF).

  19. Smart Grid Enabled EVSE

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2015-01-12

    The combined team of GE Global Research, Federal Express, National Renewable Energy Laboratory, and Consolidated Edison has successfully achieved the established goals contained within the Department of Energy’s Smart Grid Capable Electric Vehicle Supply Equipment funding opportunity. The final program product, shown charging two vehicles in Figure 1, reduces by nearly 50% the total installed system cost of the electric vehicle supply equipment (EVSE) as well as enabling a host of new Smart Grid enabled features. These include bi-directional communications, load control, utility message exchange and transaction management information. Using the new charging system, Utilities or energy service providers will now be able to monitor transportation related electrical loads on their distribution networks, send load control commands or preferences to individual systems, and then see measured responses. Installation owners will be able to authorize usage of the stations, monitor operations, and optimally control their electricity consumption. These features and cost reductions have been developed through a total system design solution.

  20. Smart Grid Enabled EVSE

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2014-10-15

    The combined team of GE Global Research, Federal Express, National Renewable Energy Laboratory, and Consolidated Edison has successfully achieved the established goals contained within the Department of Energy’s Smart Grid Capable Electric Vehicle Supply Equipment funding opportunity. The final program product, shown charging two vehicles in Figure 1, reduces by nearly 50% the total installed system cost of the electric vehicle supply equipment (EVSE) as well as enabling a host of new Smart Grid enabled features. These include bi-directional communications, load control, utility message exchange and transaction management information. Using the new charging system, Utilities or energy service providers will now be able to monitor transportation related electrical loads on their distribution networks, send load control commands or preferences to individual systems, and then see measured responses. Installation owners will be able to authorize usage of the stations, monitor operations, and optimally control their electricity consumption. These features and cost reductions have been developed through a total system design solution.

  1. Using mixed-methods research to study the quality of life of coeliac women.

    Science.gov (United States)

    Rodríguez Almagro, Julián; Hernández Martínez, Antonio; Solano Ruiz, María Carmen; Siles González, José

    2017-04-01

    To research the quality of life of Spanish women with coeliac disease. Women with coeliac disease express lower quality of life than men with coeliac disease. Explanatory sequential approach using mixed methods and with a gender perspective. The research was carried out between May and July 2015. In its quantitative stage, it aimed to determine the health-related quality of life in a representative sample (n = 1097) of Spanish adult women with coeliac disease using a specific questionnaire named Coeliac Disease-Quality of Life. In its qualitative phase, it aimed to describe the life experiences of a woman with coeliac disease in a qualitative manner by means of interviews (n = 19) with a semistructured script. Quantitative data were analysed using spss version 20 and presented in descriptive statistics. Qualitative data were analysed using the directed content analysis. The quantitative process gave us the values on the four aspects studied: dysphoria, disease limitations, health problems and inadequate treatment. These aspects allowed us to create a qualitative process, based on which we generated an interview, from which four larger categories emerged. These categories were feelings at diagnosis, limitations in day-to-day life, social perceptions of the disease and personal meanings of coeliac disease. Thus, both phases of our project are totally connected. There was a high level of congruence between quantitative scores and narratives. This study shows us the strong points of mixed-methods strategy in health sciences. The mixed-methods strategy gave us a wider view of the experience of women living with coeliac disease. In our case, a strength and not a limitation is having performed the quality of life study in women with coeliac disease using a mixed methodology, approaching the experience of being a woman with coeliac disease in Spain in two different but complementary ways. The quantitative and qualitative data allowed us to interpret the experiences of

  2. Open Architecture as an Enabler for FORCEnet

    Science.gov (United States)

    2006-09-01

    Functional Area Manager FCP Fire Control Picture FCS Fire Control Solution FCQ Fire Control Quality FFBD Functional Flow Block Diagram Fn/OA FORCEnet...a) Firing Unit (FRU) receive Fire Control Quality ( FCQ ) data on threat from Remote Unit(s) (RUs). b) Validate FCQ data, enable FRU to act. c...Maintain Common Operational Picture (COP) of local tracks. d) Develop Fire Control Solution (FCS) based on FCQ data. e) Correlate FRU FCS with RU

  3. A review on indexes and dietary assessment methods for determining the quality of diets

    Directory of Open Access Journals (Sweden)

    Ana Carolina Pinheiro Volp

    2011-12-01

    Full Text Available Objective: To summarize the different indexes most frequently used to evaluate the quality of diets, as well as the dietary assessment methods used for scoring, pointing out their advantages and disadvantages. Methods: We performed a literature search, with no daterestriction, on primary indexed sources and in the databases SciELO, PubMed, Medline, Lilacs, Dedalus and ILSI Web of Knowledge. The keywords used were diet (ary quality, diet (ary patterns, diet quality index, Mediterranean diet and nutrition. Then, the cited references were reviewed, classifying the information by index. Results: The most widely indexes used are Diet Quality Index, Healthy Eating Index and Alternative Mediterranean Diet Score, using the food frequency questionnaire or a combination of the 24-hour recall and food (s record (s. Conclusion: The determination of feeding patterns through indices is a relatively easy process; however, to have confidence in the results is necessary to know the biases thateach index and instrument has, as well as its construction and punctuation.

  4. Hyperspectral Imaging as a Rapid Quality Control Method for Herbal Tea Blends

    Directory of Open Access Journals (Sweden)

    Majolie Djokam

    2017-03-01

    Full Text Available In South Africa, indigenous herbal teas are enjoyed due to their distinct taste and aroma. The acclaimed health benefits of herbal teas include the management of chronic diseases such as hypertension and diabetes. Quality control of herbal teas has become important due to the availability of different brands of varying quality and the production of tea blends. The potential of hyperspectral imaging as a rapid quality control method for herbal tea blends from rooibos (Aspalathus linearis, honeybush (Cyclopia intermedia, buchu (Agathosma Betulina and cancerbush (Sutherlandia frutescens was investigated. Hyperspectral images of raw materials and intact tea bags were acquired using a sisuChema shortwave infrared (SWIR hyperspectral pushbroom imaging system (920–2514 nm. Principal component analysis (PCA plots showed clear discrimination between raw materials. Partial least squares discriminant analysis (PLS-DA models correctly predicted the raw material constituents of each blend and accurately determined the relative proportions. The results were corroborated independently using ultra-high performance liquid chromatography coupled to mass spectrometry (UHPLC-MS. This study demonstrated the application of hyperspectral imaging coupled with chemometric modelling as a reliable, rapid and non-destructive quality control method for authenticating herbal tea blends and to determine relative proportions in a tea bag.

  5. Automated quality control methods for sensor data: a novel observatory approach

    Directory of Open Access Journals (Sweden)

    J. R. Taylor

    2012-12-01

    Full Text Available National and international networks and observatories of terrestrial-based sensors are emerging rapidly. As such, there is demand for a standardized approach to data quality control, as well as interoperability of data among sensor networks. The National Ecological Observatory Network (NEON has begun constructing their first terrestrial observing sites with 60 locations expected to be distributed across the US by 2017. This will result in over 14 000 automated sensors recording more than > 100 Tb of data per year. These data are then used to create other datasets and subsequent "higher-level" data products. In anticipation of this challenge, an overall data quality assurance plan has been developed and the first suite of data quality control measures defined. This data-driven approach focuses on automated methods for defining a suite of plausibility test parameter thresholds. Specifically, these plausibility tests scrutinize data range, persistence, and stochasticity on each measurement type by employing a suite of binary checks. The statistical basis for each of these tests is developed and the methods for calculating test parameter thresholds are explored here. While these tests have been used elsewhere, we apply them in a novel approach by calculating their relevant test parameter thresholds. Finally, implementing automated quality control is demonstrated with preliminary data from a NEON prototype site.

  6. Automated quality control methods for sensor data: a novel observatory approach

    Directory of Open Access Journals (Sweden)

    J. R. Taylor

    2013-07-01

    Full Text Available National and international networks and observatories of terrestrial-based sensors are emerging rapidly. As such, there is demand for a standardized approach to data quality control, as well as interoperability of data among sensor networks. The National Ecological Observatory Network (NEON has begun constructing their first terrestrial observing sites, with 60 locations expected to be distributed across the US by 2017. This will result in over 14 000 automated sensors recording more than > 100 Tb of data per year. These data are then used to create other datasets and subsequent "higher-level" data products. In anticipation of this challenge, an overall data quality assurance plan has been developed and the first suite of data quality control measures defined. This data-driven approach focuses on automated methods for defining a suite of plausibility test parameter thresholds. Specifically, these plausibility tests scrutinize the data range and variance of each measurement type by employing a suite of binary checks. The statistical basis for each of these tests is developed, and the methods for calculating test parameter thresholds are explored here. While these tests have been used elsewhere, we apply them in a novel approach by calculating their relevant test parameter thresholds. Finally, implementing automated quality control is demonstrated with preliminary data from a NEON prototype site.

  7. Implementing Quality Criteria in Designing and Conducting a Sequential Quan [right arrow] Qual Mixed Methods Study of Student Engagement with Learning Applied Research Methods Online

    Science.gov (United States)

    Ivankova, Nataliya V.

    2014-01-01

    In spite of recent methodological developments related to quality assurance in mixed methods research, practical examples of how to implement quality criteria in designing and conducting sequential QUAN [right arrow] QUAL mixed methods studies to ensure the process is systematic and rigorous remain scarce. This article discusses a three-step…

  8. Implementing Quality Criteria in Designing and Conducting a Sequential Quan [right arrow] Qual Mixed Methods Study of Student Engagement with Learning Applied Research Methods Online

    Science.gov (United States)

    Ivankova, Nataliya V.

    2014-01-01

    In spite of recent methodological developments related to quality assurance in mixed methods research, practical examples of how to implement quality criteria in designing and conducting sequential QUAN [right arrow] QUAL mixed methods studies to ensure the process is systematic and rigorous remain scarce. This article discusses a three-step…

  9. A method based on IHS cylindrical transform model for quality assessment of image fusion

    Science.gov (United States)

    Zhu, Xiaokun; Jia, Yonghong

    2005-10-01

    Image fusion technique has been widely applied to remote sensing image analysis and processing, and methods for quality assessment of image fusion in remote sensing have also become the research issues at home and abroad. Traditional assessment methods combine calculation of quantitative indexes and visual interpretation to compare fused images quantificationally and qualitatively. However, in the existing assessment methods, there are two defects: on one hand, most imdexes lack the theoretic support to compare different fusion methods. On the hand, there is not a uniform preference for most of the quantitative assessment indexes when they are applied to estimate the fusion effects. That is, the spatial resolution and spectral feature could not be analyzed synchronously by these indexes and there is not a general method to unify the spatial and spectral feature assessment. So in this paper, on the basis of the approximate general model of four traditional fusion methods, including Intensity Hue Saturation(IHS) triangle transform fusion, High Pass Filter(HPF) fusion, Principal Component Analysis(PCA) fusion, Wavelet Transform(WT) fusion, a correlation coefficient assessment method based on IHS cylindrical transform is proposed. By experiments, this method can not only get the evaluation results of spatial and spectral features on the basis of uniform preference, but also can acquire the comparison between fusion image sources and fused images, and acquire differences among fusion methods. Compared with the traditional assessment methods, the new methods is more intuitionistic, and in accord with subjective estimation.

  10. A novel method for evaluating and improving the 1H-MRSI glioma data quality

    Institute of Scientific and Technical Information of China (English)

    YUAN Kehong; LU Hongyu; BAO Shanglian; CHEN Qiansheng; LI Shaowu; DUAN Chaijie

    2005-01-01

    Metabolic information obtained by proton magnetic resonance spectroscopic imaging (1H-MRSI) has been approved to be a powerful tool to identify either benign or malignant glioma, as well as to confirm the tumor level. However, 1H-MRSI data are affected by various factors, such as the thermal noise, eddy currents, susceptibility artifacts, and rigid body motion. To get accurate quantitative metabolic information, the key problem is to assess the 1H-MRSI data quality. In this paper, we introduce a new evaluating system to filter the data, and a new method, called wavelet denoising method, to improve the data quality under the evaluating system. Experimental results on 1H-MRSI glioma data demonstrate that preprocessing is prerequisite and the proposed algorithm with evaluating system is effective.

  11. Use of quality management methods in the transition from efficacious prevention programs to effective prevention services.

    Science.gov (United States)

    Daniels, Vicki-Smith; Sandler, Irwin; Wolchik, Sharlene

    2008-06-01

    This paper applies concepts and methods developed in management to translate efficacious prevention programs into effective prevention services. The paper describes Quality Function Deployment (QFD) as a method for structured planning and development that connects the needs and wants of the consumer with the design of the product or service. The paper describes basic tools used in quality management, and discusses how they might be applied to prepare a prevention program for implementation by community agencies. Prevention programs are conceptualized as having multiple consumers (i.e., stakeholders), including the participants who receive the service, the service providers, the organizations that deliver the program, and the researchers who evaluate the programs. As an illustration of one step in the application of QFD to translate efficacious prevention programs into effective prevention services, analysis of the needs and preferences of Family Courts for the implementation of an the New Beginnings Program is presented.

  12. Effect of thawing methods on frozen semen quality of yak (Poephagus grunniens L. bulls

    Directory of Open Access Journals (Sweden)

    Binod Kumar Dutta Borah

    2015-07-01

    Full Text Available Aim: To evaluate different thawing temperatures and duration on the post-thaw semen quality of Indian yaks bulls. Materials and Methods: Semen ejaculates from four different yak bulls were collected using artificial vagina method and extended with tris extender containing 6.4% glycerol at 35°C, cooled gradually from 35°C to 5°C at 1°C/3 min and equilibrated at 4-5°C for 4 h and frozen in French mini straws using a programmable bio-freezer and finally stored in liquid nitrogen.Thawing of frozen semen straws was carried out using three methods i.e., 35°C for 60 s (thawing method I, 37°C for 30 s (thawing method II and 75°C for 9 s (thawing method III.The post-thaw semen quality parameters assessed were sperm motility, percent live sperm, hypo-osmotic swelling test (HOST-reacted sperm, acrosomal changes, and alanine aminotransferase (ALT and aspartate aminotransferase (AST activities in the extracellular media. Results: The percent sperm motility, total incidence of acrosomal changes, and extracellular release of AST varied significantly (p<0.01 between thawing methods but live sperm and HOST-reacted sperm did not vary significantly between thawing methods.The percent sperm motility of frozen yak semen for thawing method III was significantly (p<0.05 higher than that for thawing methods I and II, the difference between thawing methods I and II being non-significant. The critical difference test revealed that the total incidence of acrosomal changes and extracellular release of AST were significantly (p<0.05 lower when thawing was done using methods I and II than in method III. Conclusion: On the basis of the present experiment, we can conclude that barring the post-thaw sperm motility, thawing of frozen yak semen in water either at 35°C for 60 s or 37°C for 30 s gives better post-thaw semen quality than at 75°C for 09 s.

  13. Local motion-compensated method for high-quality 3D coronary artery reconstruction.

    Science.gov (United States)

    Liu, Bo; Bai, Xiangzhi; Zhou, Fugen

    2016-12-01

    The 3D reconstruction of coronary artery from X-ray angiograms rotationally acquired on C-arm has great clinical value. While cardiac-gated reconstruction has shown promising results, it suffers from the problem of residual motion. This work proposed a new local motion-compensated reconstruction method to handle this issue. An initial image was firstly reconstructed using a regularized iterative reconstruction method. Then a 3D/2D registration method was proposed to estimate the residual vessel motion. Finally, the residual motion was compensated in the final reconstruction using the extended iterative reconstruction method. Through quantitative evaluation, it was found that high-quality 3D reconstruction could be obtained and the result was comparable to state-of-the-art method.

  14. The Optimum Production Method for Quality Improvement of Recycled Aggregates Using Sulfuric Acid and the Abrasion Method

    Science.gov (United States)

    Kim, Haseog; Park, Sangki; Kim, Hayong

    2016-01-01

    There has been increased deconstruction and demolition of reinforced concrete structures due to the aging of the structures and redevelopment of urban areas resulting in the generation of massive amounts of construction. The production volume of waste concrete is projected to increase rapidly over 100 million tons by 2020. However, due to the high cement paste content, recycled aggregates have low density and high absorption ratio. They are mostly used for land reclamation purposes with low added value instead of multiple approaches. This study was performed to determine an effective method to remove cement paste from recycled aggregates by using the abrasion and substituting the process water with acidic water. The aim of this study is to analyze the quality of the recycled fine aggregates produced by a complex method and investigate the optimum manufacturing conditions for recycled fine aggregates based on the design of experiment. The experimental parameters considered were water ratio, coarse aggregate ratio, and abrasion time and, as a result of the experiment, data concerning the properties of recycled sand were obtained. It was found that high-quality recycled fine aggregates can be obtained with 8.57 min of abrasion-crusher time and a recycled coarse aggregate ratio of over 1.5. PMID:27483298

  15. The Optimum Production Method for Quality Improvement of Recycled Aggregates Using Sulfuric Acid and the Abrasion Method

    Directory of Open Access Journals (Sweden)

    Haseog Kim

    2016-07-01

    Full Text Available There has been increased deconstruction and demolition of reinforced concrete structures due to the aging of the structures and redevelopment of urban areas resulting in the generation of massive amounts of construction. The production volume of waste concrete is projected to increase rapidly over 100 million tons by 2020. However, due to the high cement paste content, recycled aggregates have low density and high absorption ratio. They are mostly used for land reclamation purposes with low added value instead of multiple approaches. This study was performed to determine an effective method to remove cement paste from recycled aggregates by using the abrasion and substituting the process water with acidic water. The aim of this study is to analyze the quality of the recycled fine aggregates produced by a complex method and investigate the optimum manufacturing conditions for recycled fine aggregates based on the design of experiment. The experimental parameters considered were water ratio, coarse aggregate ratio, and abrasion time and, as a result of the experiment, data concerning the properties of recycled sand were obtained. It was found that high-quality recycled fine aggregates can be obtained with 8.57 min of abrasion-crusher time and a recycled coarse aggregate ratio of over 1.5.

  16. Comparative analysis of different methods for evaluating quality of Quercus ilex seedlings inoculated with Tuber melanosporum.

    Science.gov (United States)

    Andrés-Alpuente, Antonio; Sánchez, Sergio; Martín, María; Aguirre, Angel Javier; Barriuso, Juan J

    2014-04-01

    The quality of seedlings colonized by Tuber melanosporum is one of the main factors that contributes to the success or failure of a truffle crop. Truffle cultivation has quickly grown in European countries and elsewhere, so a commonly shared seedling evaluation method is needed. Five evaluation methods are currently published in the literature: three are used in Spain and two in France and Italy. Although all estimate the percentage colonization by T. melanosporum mycorrhizae, they do it in different ways. Two methods also estimate total number of mycorrhizae per seedling. Most are destructive. In this work, ten batches of holm oak seedlings inoculated with T. melanosporum from two different nurseries were evaluated by means of the five methods noted above. Some similarity was detected between the percentages of T. melanosporum mycorrhizae estimated by each method but not in their ability to assess the suitability of each batch. We discuss the advantages and disadvantages for each method and suggest approaches to reach consensus within the truffle culture industry for certifying mycorrhizal colonization by T. melanosporum and seedling quality.

  17. Impact Assessment of Various Methods for Control of Synchronous Generator Excitation on Quality of Transient Processes

    Directory of Open Access Journals (Sweden)

    Y. D. Filipchik

    2011-01-01

    Full Text Available The paper considers an impact of various methods for control of an exciting current pertaining to a synchronous generator on the nature of transient processes. A control algorithm for the exciting current in relation to changes in sliding and acceleration of a generator rotor has been proposed in the paper. The algorithm makes it possible to improve quality of the transient processes due to reduction of oscillation range concerning as an active power so a δ-angle as well.

  18. Method and apparatus for improving the quality and efficiency of ultrashort-pulse laser machining

    Science.gov (United States)

    Stuart, Brent C.; Nguyen, Hoang T.; Perry, Michael D.

    2001-01-01

    A method and apparatus for improving the quality and efficiency of machining of materials with laser pulse durations shorter than 100 picoseconds by orienting and maintaining the polarization of the laser light such that the electric field vector is perpendicular relative to the edges of the material being processed. Its use is any machining operation requiring remote delivery and/or high precision with minimal collateral dames.

  19. Objective Evaluation Method of Steering Comfort Based on Movement Quality Evaluation of Driver Steering Maneuver

    Institute of Scientific and Technical Information of China (English)

    YANG Yiyong; LIU Yahui; WANG Man; JI Run; JI Xuewu

    2014-01-01

    The existing research of steering comfort mainly focuses on the subjective evaluation, aiming at designing and optimizing the steering system. In the development of steering system, especially the evaluation of steering comfort, the objective evaluation methods considered the kinematic characteristics of driver steering maneuver are not proposed, which means that the objective evaluation of steering cannot be conducted with the evaluation of kinematic characteristics of driver in steering maneuver. In order to propose the objective evaluation methods of steering comfort, the evaluation of steering movement quality of driver is developed on the basis of the study of the kinematic characteristics of steering maneuver. First, the steering motion trajectories of the driver in both comfortable and certain extreme uncomfortable operation conditions are detected using the Vicon motion capture system. The operation conditions are under the restrictions of the vertical height and horizontal distance between steering wheel center and the H-point of driver, and the steering resisting torque else. Next, the movement quality evaluation of driver steering maneuver is assessed using twelve kinds of evaluation indices based on the kinematic analyses of the steering motion trajectories to propose an objective evaluation method. Finally, an integrated discomfort index of steering maneuver is proposed on the basis of the regression analysis of subjective evaluation rating and the movement quality evaluation indices, including the Jerk, Discomfort and Joint Torque indices. The test results show that the proposed integrated discomfort index gives a good fitting with the subjective evaluation of discomfort, which means it can be used to evaluate or predict the discomfort level of steering maneuver. This paper proposes an objective evaluation method of steering comfort based on the movement quality evaluation of driver steering maneuver.

  20. Quality Evaluation of Potentilla fruticosa L. by High Performance Liquid Chromatography Fingerprinting Associated with Chemometric Methods

    OpenAIRE

    Wei Liu; Dongmei Wang; Jianjun Liu; Dengwu Li; Dongxue Yin

    2016-01-01

    The present study was performed to assess the quality of Potentilla fruticosa L. sampled from distinct regions of China using high performance liquid chromatography (HPLC) fingerprinting coupled with a suite of chemometric methods. For this quantitative analysis, the main active phytochemical compositions and the antioxidant activity in P. fruticosa were also investigated. Considering the high percentages and antioxidant activities of phytochemicals, P. fruticosa samples from Kangding, Sichua...

  1. Quality control analytical methods: microbial limit tests for nonsterile pharmaceuticals, Part 1.

    Science.gov (United States)

    Vu, Nicole; Lou, Jessica R; Kupiec, Thomas C

    2014-01-01

    Contamination of pharmaceuticals with microorganisms may lead to deleterious effects on the therapeutic properties of the drug, and may potentially cause injuries to intended recipients. Cases of contaminated nonsterile products have been reported in increasing numbers, and often associated with the presence of objectionable microorganisms. Methods for detection of these organisms are described in three major Pharmacopeias. Their functions and their limitations in the examination of microbiological quality for nonsterile products will be reviewed in this report.

  2. Improving the quality perception of digital images using modified method of the eye aberration correction

    Science.gov (United States)

    Kvyetnyy, Roman; Sofina, Olga; Orlyk, Pavel; Utreras, Andres J.; Smolarz, Andrzej; Wójcik, Waldemar; Orazalieva, Sandugash

    2016-09-01

    A new approach to solve the problem of image correction to improve the quality perception of graphic information by people with aberrations of the eye optical system is considered in given article. The model of higher order aberrations which may appear in the human eye optical system is described. The developed approach is based on the pre-processing of digital images and applying of the filtration methods to the adjusted images.

  3. An Efficient Quality-Related Fault Diagnosis Method for Real-Time Multimode Industrial Process

    Directory of Open Access Journals (Sweden)

    Kaixiang Peng

    2017-01-01

    Full Text Available Focusing on quality-related complex industrial process performance monitoring, a novel multimode process monitoring method is proposed in this paper. Firstly, principal component space clustering is implemented under the guidance of quality variables. Through extraction of model tags, clustering information of original training data can be acquired. Secondly, according to multimode characteristics of process data, the monitoring model integrated Gaussian mixture model with total projection to latent structures is effective after building the covariance description form. The multimode total projection to latent structures (MTPLS model is the foundation of problem solving about quality-related monitoring for multimode processes. Then, a comprehensive statistics index is defined which is based on the posterior probability of the monitored samples belonging to each Gaussian component in the Bayesian theory. After that, a combined index is constructed for process monitoring. Finally, motivated by the application of traditional contribution plot in fault diagnosis, a gradient contribution rate is applied for analyzing the variation of variable contribution rate along samples. Our method can ensure the implementation of online fault monitoring and diagnosis for multimode processes. Performances of the whole proposed scheme are verified in a real industrial, hot strip mill process (HSMP compared with some existing methods.

  4. An Efficient Feature Extraction Method Based on Entropy for Power Quality Disturbance

    Directory of Open Access Journals (Sweden)

    P. Kailasapathi

    2014-09-01

    Full Text Available This study explores the applicability of entropy defined as thermodynamic state variable introduced by German Physicists Rudolf clausius and also presents the concepts and application of said state variable as a measure of system disorganization. Later an entropy-based feature Analysis method for power quality disturbance analysis has been proposed. Feature extraction of a disturbed power signal provides information that helps to detect the responsible fault for power quality disturbance. A precise and faster feature extraction tool helps power engineers to monitor and maintain power disturbances more efficiently. Firstly, the decomposition coefficients are obtained by applying 10-level wavelet multi resolution analysis to the signals (normal, sag, swell, outage, harmonic and sag with harmonic and swell with harmonic generated by using the parametric equations. Secondly, a combined feature vector is obtained from standard deviation of these features after distinctive features for each signal are extracted by applying the energy, the Shannon entropy and the log-energy entropy methods to decomposition coefficients. Finally the entropy methods detect the different types of power quality disturbance.

  5. Water quality assessment using water quality index and geographical information system methods in the coastal waters of Andaman Sea, India.

    Science.gov (United States)

    Jha, Dilip Kumar; Devi, Marimuthu Prashanthi; Vidyalakshmi, Rajendran; Brindha, Balan; Vinithkumar, Nambali Valsalan; Kirubagaran, Ramalingam

    2015-11-15

    Seawater samples at 54 stations in the year 2011-2012 from Chidiyatappu, Port Blair, Rangat and Aerial Bays of Andaman Sea, have been investigated in the present study. Datasets obtained have been converted into simple maps using coastal water quality index (CWQI) and Geographical Information System (GIS) based overlay mapping technique to demarcate healthy and polluted areas. Analysis of multiple parameters revealed poor water quality in Port Blair and Rangat Bays. The anthropogenic activities may be the likely cause for poor water quality. Whereas, good water quality was witnessed at Chidiyatappu Bay. Higher CWQI scores were perceived in the open sea. However, less exploitation of coastal resources owing to minimal anthropogenic activity indicated good water quality index at Chidiyatappu Bay. This study is an attempt to integrate CWQI and GIS based mapping technique to derive a reliable, simple and useful output for water quality monitoring in coastal environment.

  6. Microbiological safety and quality of Mozzarella cheese assessed by the microbiological survey method.

    Science.gov (United States)

    Losito, Francesca; Arienzo, Alyexandra; Bottini, Giorgia; Priolisi, Francesca Romana; Mari, Alberto; Antonini, Giovanni

    2014-01-01

    Dairy products are characterized by reduced shelf life because they are an excellent growth medium for a wide range of microorganisms. For this reason, it is important to monitor the microbiological quality of dairy products and, in particular, the total viable count and concentration of Escherichia coli, as they are indicators of the hygienic state of these products. In addition, in dairy products such as Mozzarella cheese, it is important to monitor the concentration of lactic acid bacteria (LAB), as they are the major components of starter cultures used in cheese production, contributing to the taste and texture of fermented products and inhibiting food spoilage bacteria by producing growth-inhibiting substances. For these reasons, to ensure the quality and safety of their products, cheese makers should monitor frequently, during fresh cheese production, the concentration of LAB and spoilage bacteria. However, usually, small- to medium-size dairy factories do not have an internal microbiological laboratory and external laboratories of analysis are often too expensive and require several days for the results. Compared with traditional methods, the microbiological survey (MBS) method developed by Roma Tre University (Rome, Italy) allows faster and less-expensive microbiological analyses to be conducted wherever they are necessary, without the need for a microbiological laboratory or any instrumentation other than MBS vials and a thermostat. In this paper, we report the primary validation of the MBS method to monitor LAB concentration in Mozzarella cheese and the analysis, using the MBS method, of total viable count, E. coli, and LAB concentrations in the production line of Mozzarella cheese as well as during the shelf life of the product stored at 20°C. The results obtained indicate that the MBS method may be successfully used by small- to medium-size dairy factories that do not have an internal microbiological laboratory. Using the MBS method, these dairy

  7. Sensory and rapid instrumental methods as a combined tool for quality control of cooked ham.

    Science.gov (United States)

    Barbieri, Sara; Soglia, Francesca; Palagano, Rosa; Tesini, Federica; Bendini, Alessandra; Petracci, Massimiliano; Cavani, Claudio; Gallina Toschi, Tullia

    2016-11-01

    In this preliminary investigation, different commercial categories of Italian cooked pork hams have been characterized using an integrated approach based on both sensory and fast instrumental measurements. For these purposes, Italian products belonging to different categories (cooked ham, "selected" cooked ham and "high quality" cooked ham) were evaluated by sensory descriptive analysis and by the application of rapid tools such as image analysis by an "electronic eye" and texture analyzer. The panel of trained assessors identified and evaluated 10 sensory descriptors able to define the quality of the products. Statistical analysis highlighted that sensory characteristics related to appearance and texture were the most significant in discriminating samples belonged to the highest (high quality cooked hams) and the lowest (cooked hams) quality of the product whereas the selected cooked hams, showed intermediate characteristics. In particular, high quality samples were characterized, above all, by the highest intensity of pink intensity, typical appearance and cohesiveness, and, at the same time, by the lowest intensity of juiciness; standard cooked ham samples showed the lowest intensity of all visual attributes and the highest value of juiciness, whereas the intermediate category (selected cooked ham) was not discriminated from the other. Also physical-rheological parameters measured by electronic eye and texture analyzer were effective in classifying samples. In particular, the PLS model built with data obtained from the electronic eye showed a satisfactory performance in terms of prediction of the pink intensity and presence of fat attributes evaluated during the sensory visual phase. This study can be considered a first application of this combined approach that could represent a suitable and fast method to verify if the meat product purchased by consumer match its description in terms of compliance with the claimed quality.

  8. An Overview on Novel Microbial Determination Methods in Pharmaceutical and Food Quality Control

    Directory of Open Access Journals (Sweden)

    Mahboob Nemati

    2016-09-01

    Full Text Available Traditional microbiological methods tend to be labor-intensive and time-consuming. Rapid and novel methods in microbiological tests provide more sensitive, precise and reproducible results compared with conventional methods. In microbiology, the most rapid testing methods belong to the field of biotechnology such as PCR, ELISA, ATP bioluminescence and etc. Nevertheless impedance microbiology, biosensors and analytical procedures to determine microbial constituents are of significance. The present review article was conducted using internet databases and related scientific literatures and articles that provide information on developments in the rapid methods in microbiology. The main focus is on the application of rapid methods in microbial quality control of pharmaceutical products. Reviewed literature showed that rapid methods and automation in microbiology is an advanced area for studying and applying of improved methods in the early detection, and characterization of microorganisms and their products in food, pharmaceutical and cosmetic industrials as well as environmental monitoring and clinical applications. It can be concluded that rapid methods and automation in microbiology should continue as potent and efficient technologies to develop the novel tests to be performed in the future because of the ever-increasing concerns about the safety of food and pharmaceutical products. However the main issues to be considered are the scale up of developed methods and the regulatory requirements.

  9. An Overview on Novel Microbial Determination Methods in Pharmaceutical and Food Quality Control

    Science.gov (United States)

    Nemati, Mahboob; Hamidi, Aliasghar; Maleki Dizaj, Solmaz; Javaherzadeh, Vahid; Lotfipour, Farzaneh

    2016-01-01

    Traditional microbiological methods tend to be labor-intensive and time-consuming. Rapid and novel methods in microbiological tests provide more sensitive, precise and reproducible results compared with conventional methods. In microbiology, the most rapid testing methods belong to the field of biotechnology such as PCR, ELISA, ATP bioluminescence and etc. Nevertheless impedance microbiology, biosensors and analytical procedures to determine microbial constituents are of significance. The present review article was conducted using internet databases and related scientific literatures and articles that provide information on developments in the rapid methods in microbiology. The main focus is on the application of rapid methods in microbial quality control of pharmaceutical products. Reviewed literature showed that rapid methods and automation in microbiology is an advanced area for studying and applying of improved methods in the early detection, and characterization of microorganisms and their products in food, pharmaceutical and cosmetic industrials as well as environmental monitoring and clinical applications. It can be concluded that rapid methods and automation in microbiology should continue as potent and efficient technologies to develop the novel tests to be performed in the future because of the ever-increasing concerns about the safety of food and pharmaceutical products. However the main issues to be considered are the scale up of developed methods and the regulatory requirements. PMID:27766214

  10. Optimizing Scoring and Sampling Methods for Assessing Built Neighborhood Environment Quality in Residential Areas

    Directory of Open Access Journals (Sweden)

    Joel Adu-Brimpong

    2017-03-01

    Full Text Available Optimization of existing measurement tools is necessary to explore links between aspects of the neighborhood built environment and health behaviors or outcomes. We evaluate a scoring method for virtual neighborhood audits utilizing the Active Neighborhood Checklist (the Checklist, a neighborhood audit measure, and assess street segment representativeness in low-income neighborhoods. Eighty-two home neighborhoods of Washington, D.C. Cardiovascular Health/Needs Assessment (NCT01927783 participants were audited using Google Street View imagery and the Checklist (five sections with 89 total questions. Twelve street segments per home address were assessed for (1 Land-Use Type; (2 Public Transportation Availability; (3 Street Characteristics; (4 Environment Quality and (5 Sidewalks/Walking/Biking features. Checklist items were scored 0–2 points/question. A combinations algorithm was developed to assess street segments’ representativeness. Spearman correlations were calculated between built environment quality scores and Walk Score®, a validated neighborhood walkability measure. Street segment quality scores ranged 10–47 (Mean = 29.4 ± 6.9 and overall neighborhood quality scores, 172–475 (Mean = 352.3 ± 63.6. Walk scores® ranged 0–91 (Mean = 46.7 ± 26.3. Street segment combinations’ correlation coefficients ranged 0.75–1.0. Significant positive correlations were found between overall neighborhood quality scores, four of the five Checklist subsection scores, and Walk Scores® (r = 0.62, p < 0.001. This scoring method adequately captures neighborhood features in low-income, residential areas and may aid in delineating impact of specific built environment features on health behaviors and outcomes.

  11. Improved Reconstruction Quality of Bioluminescent Images by Combining SP3 Equations and Bregman Iteration Method

    Directory of Open Access Journals (Sweden)

    Qiang Wu

    2013-01-01

    Full Text Available Bioluminescence tomography (BLT has a great potential to provide a powerful tool for tumor detection, monitoring tumor therapy progress, and drug development; developing new reconstruction algorithms will advance the technique to practical applications. In the paper, we propose a BLT reconstruction algorithm by combining SP3 equations and Bregman iteration method to improve the quality of reconstructed sources. The numerical results for homogeneous and heterogeneous phantoms are very encouraging and give significant improvement over the algorithms without the use of SP3 equations and Bregman iteration method.

  12. Quality assessment of layer-structured semiconductor single crystals by nuclear quadruple resonance method

    Science.gov (United States)

    Samila, Andriy; Khandozhko, Alexander; Lastivka, Galina; Politansky, Leonid; Khandozhko, Victor

    2015-11-01

    A method for quality assessment of layer-structured semiconductor single crystals (InSe, GaSe, GaS) grown in evacuated ampoules by the Bridgman technique is proposed. For this purpose, nuclear quadruple resonance method with a consecutive scanning of the entire sample volume and evaluation of crystal perfection by the resulting spectra is used. Effective interaction between high-frequency field and crystal and, accordingly, restriction of scanning area of sample under study is provided with the use of a two-way saddle-shaped coil for a nuclear quadruple resonance spectrometer.

  13. Analysis of the method quality function deployment "qfd" in preventive services police

    Directory of Open Access Journals (Sweden)

    Lauro Soares de Freitas

    2015-02-01

    Full Text Available Despite of the significant contribution of QFD for the construction of the theoretical framework for managing the development of new products and services, there is an embryonic implementation in the public sector. The purpose of this article is to analyze the application of the method in the context of public safety, and the study was delimited to the School Patrol in the Military Police of Minas Gerais. Action research was the research strategy chosen and qualitative and quantitative methods were used to collect and analyze data. The QFD method proved to be effective for: systematize a large set of internal and external corporate information, facilitating the subsequent planning of policing; promote a dynamic oriented and structured in encounters between police and the community; identify the needs of public school and prioritize activities policing which better fulfill these desires; and to understand the ability of service of a School Patrol Unit. Moreover, the police service has a unique set of characteristics that partially hindered planning service by QFD. This service does not have a specific market niche, being a service of law and not by purchase. Also relies on legal aspects and regulates behaviors, generating rejection. Although this particular nature, two factors favored the application of the method: the institutionalization of the philosophy of community policing in the organization and to familiarizing officers with management concepts and quality. The final conclusion is that the QFD method was presented as a promising tool for improving the quality of Brazilian public services.

  14. A review of image quality assessment methods with application to computational photography

    Science.gov (United States)

    Maître, Henri

    2015-12-01

    Image quality assessment has been of major importance for several domains of the industry of image as for instance restoration or communication and coding. New application fields are opening today with the increase of embedded power in the camera and the emergence of computational photography: automatic tuning, image selection, image fusion, image data-base building, etc. We review the literature of image quality evaluation. We pay attention to the very different underlying hypotheses and results of the existing methods to approach the problem. We explain why they differ and for which applications they may be beneficial. We also underline their limits, especially for a possible use in the novel domain of computational photography. Being developed to address different objectives, they propose answers on different aspects, which make them sometimes complementary. However, they all remain limited in their capability to challenge the human expert, the said or unsaid ultimate goal. We consider the methods which are based on retrieving the parameters of a signal, mostly in spectral analysis; then we explore the more global methods to qualify the image quality in terms of noticeable defects or degradation as popular in the compression domain; in a third field the image acquisition process is considered as a channel between the source and the receiver, allowing to use the tools of the information theory and to qualify the system in terms of entropy and information capacity. However, these different approaches hardly attack the most difficult part of the task which is to measure the quality of the photography in terms of aesthetic properties. To help in addressing this problem, in between Philosophy, Biology and Psychology, we propose a brief review of the literature which addresses the problematic of qualifying Beauty, present the attempts to adapt these concepts to visual patterns and initiate a reflection on what could be done in the field of photography.

  15. Study on Rear-end Real-time Data Quality Control Method of Regional Automatic Weather Station

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    [Objective] The aim was to study the rear-end real-time data quality control method of regional automatic weather station. [Method] The basic content and steps of rear-end real-time data quality control of regional automatic weather station were introduced. Each element was treated with systematic quality control procedure. The existence of rear-end real time data of regional meteorological station in Guangxi was expounded. Combining with relevant elements and linear changes, improvement based on traditiona...

  16. Quality Prediction and Control of Reducing Pipe Based on EOS-ELM-RPLS Mathematics Modeling Method

    Directory of Open Access Journals (Sweden)

    Dong Xiao

    2014-01-01

    Full Text Available The inspection of inhomogeneous transverse and longitudinal wall thicknesses, which determines the quality of reducing pipe during the production of seamless steel reducing pipe, is lags and difficult to establish its mechanism model. Aiming at the problems, we proposed the quality prediction model of reducing pipe based on EOS-ELM-RPLS algorithm, which taking into account the production characteristics of its time-varying, nonlinearity, rapid intermission, and data echelon distribution. Key contents such as analysis of data time interval, solving of mean value, establishment of regression model, and model online prediction were introduced and the established prediction model was used in the quality prediction and iteration control of reducing pipe. It is shown through experiment and simulation that the prediction and iteration control method based on EOS-ELM-RPLS model can effectively improve the quality of steel reducing pipe, and, moreover, its maintenance cost was low and it has good characteristics of real time, reliability, and high accuracy.

  17. A novel method to construct an air quality index based on air pollution profiles.

    Science.gov (United States)

    Thach, Thuan-Quoc; Tsang, Hilda; Cao, Peihua; Ho, Lai-Ming

    2017-09-29

    Air quality indices based on the maximum of sub-indices of pollutants are easy to produce and help quantify the degree of air pollution. However, they discount the additive effects of multiple pollutants and are only sensitive to changes in highest sub-index. We propose a simple and concise method to construct an air quality index that takes into account additive effects of multiple pollutants and evaluate the extent to which this index predicts health effects. We obtained concentrations of four criteria pollutants: particulate matter with aerodynamic diameter ≤ 10μm (PM10), sulphur dioxide (SO2), nitrogen dioxide (NO2) and ozone (O3) and daily admissions to Hong Kong hospitals for cardiovascular and respiratory diseases for all ages and those 65 years or older for years 2001-2012. We derived sub-indices of the four criteria pollutants, calculated by normalizing pollutant concentrations to their respective short-term WHO Air Quality Guidelines (WHO AQG). We aggregated the sub-indices using the root-mean-power function with an optimal power to form an overall air quality index. The optimal power was determined by minimizing the sum of over- and under-estimated days. We then assessed associations between the pollution bands of the index and cardiovascular and respiratory admissions using a time-stratified case-crossover design adjusted for ambient temperature, relative. Copyright © 2017 Elsevier GmbH. All rights reserved.

  18. Method for integrated design of low energy buildings with high quality indoor environment

    DEFF Research Database (Denmark)

    Petersen, Steffen

    2008-01-01

    Energy performance and indoor environment have due to new increased regulatory demands become decisive design parameters in the building design process. In order to comply with the increased regulatory demands, we present an integrated design method which argues that the design of buildings must ...... to become the preferred method for integrated design of low energy buildings with high quality indoor environment.......Energy performance and indoor environment have due to new increased regulatory demands become decisive design parameters in the building design process. In order to comply with the increased regulatory demands, we present an integrated design method which argues that the design of buildings must...... start on room level rather than total building level. The proposed method starts with the establishment of design goals, including goals regarding energy performance and indoor environment, followed by a building physical analysis of performance-decisive parameters. This analysis is used to establish...

  19. Multi-line split DNA synthesis: a novel combinatorial method to make high quality peptide libraries

    Directory of Open Access Journals (Sweden)

    Ueno Shingo

    2004-09-01

    Full Text Available Abstract Background We developed a method to make a various high quality random peptide libraries for evolutionary protein engineering based on a combinatorial DNA synthesis. Results A split synthesis in codon units was performed with mixtures of bases optimally designed by using a Genetic Algorithm program. It required only standard DNA synthetic reagents and standard DNA synthesizers in three lines. This multi-line split DNA synthesis (MLSDS is simply realized by adding a mix-and-split process to normal DNA synthesis protocol. Superiority of MLSDS method over other methods was shown. We demonstrated the synthesis of oligonucleotide libraries with 1016 diversity, and the construction of a library with random sequence coding 120 amino acids containing few stop codons. Conclusions Owing to the flexibility of the MLSDS method, it will be able to design various "rational" libraries by using bioinformatics databases.

  20. Design and methods of the Pacific Northwest Stream Quality Assessment (PNSQA), 2015

    Science.gov (United States)

    Sheibley, Rich W.; Morace, Jennifer L.; Journey, Celeste A.; Van Metre, Peter C.; Bell, Amanda H.; Nakagaki, Naomi; Button, Daniel T.; Qi, Sharon L.

    2017-08-25

    In 2015, the U.S. Geological Survey (USGS) National Water-Quality Assessment (NAWQA) project conducted the Pacific Northwest Stream Quality Assessment (PNSQA) to investigate stream quality across the western part of the Pacific Northwest. The goal of the PNSQA was to assess the health of streams in the region by characterizing multiple water-quality factors that are stressors to in-stream aquatic life and by evaluating the relation between these stressors and the condition of biological communities. The effects of urbanization and agriculture on stream quality for the Puget Lowland and Willamette Valley Level III Ecoregions were the focus of this regional study. Findings will help inform the public and policymakers about human and environmental factors that are the most critical in affecting stream quality and, thus, provide insights into possible strategies to protect or improve the health of streams in the region.Land-use data were used in the study to identify and select sites within the region that ranged in levels of urban and agricultural development. A total of 88 sites were selected across the region—69 were on streams that explicitly spanned a range of urban land use in their watersheds, 8 were on streams in agricultural watersheds, and 11 were reference sites with little or no development in their watersheds. Depending on the type of land use, sites were sampled for contaminants, nutrients, and sediment for either a 4- or 10-week period during April, May, and June 2015. This water-quality “index period” was immediately followed with an ecological survey of all sites that included stream habitat, benthic algae, benthic macroinvertebrates, and fish. Additionally, streambed sediment was collected during the ecological survey for analysis of sediment chemistry and toxicity testing.This report provides a detailed description of the specific study components and methods of the PNSQA, including (1) surveys of stream habitat and aquatic biota, (2) discrete

  1. A Novel Method for Quality Assurance of the Cyberknife Iris Variable Aperture Collimator

    Science.gov (United States)

    Kremer, Nikolaus; Fürweger, Christoph

    2016-01-01

    Objective: To characterize a novel method for field-size quality assurance of a variable approximately circular aperture collimator by means of dose-area product measurements and to validate its practical use over two years of clinical application. Methods:  To assess methodical limitations, we analyze measurement errors due to change in linac output, beam tuning, uncertainty in MU delivery, daily factors, inherent uncertainty of the large-area parallel-plate ionisation chamber, and misalignment of the large-area parallel-plate ionisation chamber relative to the primary beam axis. To establish a baseline for quality assurance, the dose-area product is measured with the large-area parallel-plate ionisation chamber for all 12 clinical iris apertures in relation to the 60 mm fixed reference aperture. To evaluate the long-term stability of the Iris collimation system, deviation from baseline data is assessed monthly and compared to a priori derived tolerance levels. Results: Only chamber misalignment, variation in output, and uncertainty in MU delivery contribute to a combined error that is estimated at 0.2 % of the nominal field size. This is equivalent to a resolution of 0.005 mm for the 5 mm, and 0.012 mm for the 60 mm field. The method offers ease of use, small measurement time commitment, and is independent of most error sources. Over the observed period, the Iris accuray is within the tolerance levels. Conclusions:  The method is an advantageous alternative to film quality assurance with a high reliability, short measurement time, and superior accuracy in field-size determination. PMID:27382526

  2. Comparison of grape harvesting and sorting methods on factors affecting the must quality

    Directory of Open Access Journals (Sweden)

    Alessandro Parenti

    2015-04-01

    Full Text Available This study compared two harvesting techniques (manual and mechanical and three grape sorting methods (no sorting, manual, and densimetric in attempts to obtain high-quality must. The trials were carried out in 2009 and 2010 in Tuscany, Italy. The effectiveness of the harvest-sorting chain was assessed on two parameters. Substandard berries (SSB is the percentage of berries, which do not meet quality standards that enter the winemaking process, and material other than grape (MOG is a measure of the cleanliness of the berries entering the process. In the two years the trial was run the grape maturation level was widely different; in 2009 the vintage was more far mature than in 2010. With respect to SSB content and harvesting methods, in 2009 (more mature grapes hand-picking reduced SSB content, while in 2010 there were no differences between the two harvesting methods. In both years, densimetric sorting reduced SSB content, while there were no significant differences between no sorting and manual sorting. In terms of MOG content, both harvesting and sorting results were inconsistent. In 2009, MOG was lower in mechanically harvested grapes; while in 2010 it was lower in hand-picked grapes. As for sorting methods, in 2009 there were no differences in MOG, while in 2010 mechanical sorting produced better results. Our results question whether the post-harvest sorting techniques used by many estates are effective; particularly as the question has received little attention and no previous research has compared methods. Secondly, our study contributes to the debate on the effects of harvesting technique on wine quality.

  3. Enabling Europe to innovate.

    Science.gov (United States)

    Dearing, Andrew

    2007-01-19

    As activities that relate to innovation become increasingly global and open and so draw the private and public sectors into complex networks of partnerships, these activities also tend to concentrate where the ecosystem is most supportive. European public policy, which in recent years has emphasized the importance of research and development (R&D) in achieving competitive knowledge-based societies, is shifting toward approaches that address the broader qualities required of favorable ecosystems for innovation in a global economy, thereby incorporating the roles of market demand, public procurement, and regulation, as well as science, education, and industrial R&D, as part of determining effective innovation policies.

  4. Sex attribution, gender identity and quality of life in disorders of sex development due to 45,X/46,XY mosaicism: methods for clinical and psychosocial assessment

    Directory of Open Access Journals (Sweden)

    Roberta Risso

    2015-03-01

    Full Text Available The choice of sex in newborns with genital ambiguity is challenging. Information concerning the satisfaction of subjects with disorders of sex development from childhood to adulthood is required in order to address sex attribution policies. This study focuses on the methods that enable clinicians to investigate the alignment of phenotypes with gender identity and quality of life in people with disorders of this kind. These methods are presented as tools for studying a cohort of ten subjects with 45,X/46,XY mosaicism examined between 1985 and 2014 in the Department of Pediatric Endocrinology, Regina Margherita Children's Hospital, Turin: five children and five young adults, four reared as females and six as males. Clinical outcome was assessed by means of a clinical scoring system considering height, genital appearance, gonads and pubertal development. The Gender Identity Questionnaire for Children and the World Health Organization Quality of Life assessment were adopted. The four male children strongly identified with their assigned sex: male attribution was satisfactory until pubertal age. In young adults the clinical scores ranged between 55-65% for both genders. In the young male, the reduced sexual activity and the poor body image perception strongly affected his quality of life. The clinical scores of the two young female adults (60% for both were not balanced with their quality of life scores (87.5% and 68.75% respectively: individual traits and social-familial context should be investigated in order to explain these differences. Clinical and psychosocial assessment in people with disorders of sex development is mandatory in order to plan care procedures; a detailed analysis requires adequate tools. Clinical scoring system, Gender Identity Questionnaire for Children and World Health Organization Quality of Life assessment can be used to investigate the alignment of physical phenotype with gender identity and quality of life.

  5. Influence of rendering methods on yield and quality of chicken fat recovered from broiler skin

    Directory of Open Access Journals (Sweden)

    Liang-Kun Lin

    2017-06-01

    Full Text Available Objective In order to utilize fat from broiler byproducts efficiently, it is necessary to develop an appropriate rendering procedure and establish quality information for the rendered fat. A study was therefore undertaken to evaluate the influence of rendering methods on the amounts and general properties of the fat recovered from broiler skin. Methods The yield and quality of the broiler skin fat rendered through high and lower energy microwave rendering (3.6 W/g for 10 min and 2.4 W/g for 10 min for high power microwave rendering (HPMR and high power microwave rendering (LPMR, respectively, oven baking (OB, at 180°C for 40 min, and water cooking (WC, boiling for 40 min were compared. Results Microwave-rendered skin exhibited the highest yields and fat recovery rates, followed by OB, and WC fats (p<0.05. HPMR fat had the highest L*, a*, and b* values, whereas WC fat had the highest moisture content, acid values, and thiobarbituric acid (TBA values (p<0.05. There was no significant difference in the acid value, peroxide value, and TBA values between HPMR and LPMR fats. Conclusion Microwave rendering at a power level of 3.6 W/g for 10 min is suggested base on the yield and quality of chicken fat.

  6. New CVD-based method for the growth of high-quality crystalline zinc oxide layers

    Science.gov (United States)

    Huber, Florian; Madel, Manfred; Reiser, Anton; Bauer, Sebastian; Thonke, Klaus

    2016-07-01

    High-quality zinc oxide (ZnO) layers were grown using a new chemical vapour deposition (CVD)-based low-cost growth method. The process is characterized by total simplicity, high growth rates, and cheap, less hazardous precursors. To produce elementary zinc vapour, methane (CH4) is used to reduce a ZnO powder. By re-oxidizing the zinc with pure oxygen, highly crystalline ZnO layers were grown on gallium nitride (GaN) layers and on sapphire substrates with an aluminum nitride (AlN) nucleation layer. Using simple CH4 as precursor has the big advantage of good controllability and the avoidance of highly toxic gases like nitrogen oxides. In photoluminescence (PL) measurements the samples show a strong near-band-edge emission and a sharp line width at 5 K. The good crystal quality has been confirmed in high resolution X-ray diffraction (HRXRD) measurements. This new growth method has great potential for industrial large-scale production of high-quality single crystal ZnO layers.

  7. Impact of Pretreatment and Drying Methods on Quality Attributes of Onion Shreds

    Directory of Open Access Journals (Sweden)

    Nihar R. Sahoo

    2015-01-01

    Full Text Available Experiments were conducted on dry untreated onion shreds (2 mm thickness or treated with salt (5 % solution and potassium metabisulphite (0.5 % solution in convective drier at 50 °C ((46±4 % relative humidity (RH, 55 °C ((35±4 % RH, 60 °C ((28±4 % RH and 65 °C ((20±4 % RH, heat pump-assisted convective drier at 35 °C ((32±2 % RH, 40 °C ((26±2 % RH, 45 °C ((19±2 % RH and 50 °C ((15±2 % RH and microwave-assisted convective drier at four microwave power levels, i.e. 120, 240, 360 and 480 W. The quality parameters of the dried onion shreds, namely rehydration ratio, colour diff erence, pyruvic and ascorbic acid contents and sensory scores were evaluated. The quality of dehydrated onion shreds was observed to be comparatively better when treated in heat pump drier at 50 °C, followed by that in microwave-assisted convective drier at 240 W and 50 °C, and last in convective drier at 60 °C. The onion shreds pretreated with potassium metabisulphite retained better colour of the dried product irrespective of drying methods. Therefore, heat pump drying may be recommended as one of the best drying methods for onion shreds, because it maintains the fi nal product quality, which has practical importance for the food industry.

  8. The effect of a photocatalytic air purifier on indoor air quality quantified using different measuring methods

    Energy Technology Data Exchange (ETDEWEB)

    Kolarik, Barbara [Technical University of Denmark, International Centre for Indoor Environment and Energy, Faculty of Civil Engineering, Lyngby (Denmark); Silesian University of Technology, 44-100 Gliwice (Poland); Danish Building Research Institute (SBi), Department of Construction and Health, Dr Neergaards Vej 15, 2970 Hoersholm (Denmark); Wargocki, Pawel [Technical University of Denmark, International Centre for Indoor Environment and Energy, Faculty of Civil Engineering, Lyngby (Denmark); Skorek-Osikowska, Anna [Silesian University of Technology, 44-100 Gliwice (Poland); Wisthaler, Armin [Institute of Ion Physics and Applied Physics, University of Innsbruck, 6020 Innsbruck (Austria)

    2010-06-15

    The effect on indoor air quality of an air purifier based on photocatalytic oxidation (PCO) was determined by different measuring techniques: sensory assessments of air quality made by human subjects, Proton-Transfer-Reaction Mass Spectrometry (PTR-MS) and chromatographic methods (Gas Chromatography/Mass Spectrometry and High-Pressure Liquid Chromatography with UV detection). The experiment was conducted in a simulated office, ventilated with 0.6 h{sup -1}, 2.5 h{sup -1} and 6 h{sup -1}, in the presence of additional pollution sources (carpet, chipboard and linoleum). At the lowest air change rate, additional measurements were made with no pollution sources present in the office. All conditions were tested with the photocatalytic air purifier turned on and off. The results show that operation of the air purifier in the presence of pollutants emitted by building materials and furniture improves indoor air quality, as documented by sensory assessments made by human subjects. It also reduces concentrations of many chemical compounds present in the air as documented by the PTR-MS technique. For the lowest ventilation, results from measurements using the chromatographic methods have similar tendency, however many of the 50 compounds that were targeted for analysis were not detected at all, independent of whether the purifier was on or off. For the two conditions with higher ventilation the results were inconclusive. (author)

  9. An improved Gabor enhancement method for low-quality fingerprint images

    Science.gov (United States)

    Geng, Hao; Li, Jicheng; Zhou, Jinwei; Chen, Dong

    2015-10-01

    The criminal's fingerprints often refer to those fingerprints that are extracted from crime scene and have played an important role in police' investigation and cracking the cases, but these fingerprints have features such as blur, incompleteness and low-contrast of ridges. Traditional fingerprint enhancement and identification methods have some limitations and the current automated fingerprint identification system (AFIS) hasn't not been applied extensively in police' investigation. Since the Gabor filter has drawbacks such as poor efficiency, low preciseness of the extracted ridge's orientation parameters, the enhancements of low-contrast fingerprint images can't achieve the desired effects. Therefore, an improved Gabor enhancement for low-quality fingerprint is proposed in this paper. Firstly, orientation image templates with different scales were used to distinguish the orientation images in the fingerprint area, and then orientation parameters of ridge were calculated. Secondly, mean frequencies of ridge were extracted based on local window of ridge's orientation and mean frequency parameters of ridges were calculated. Thirdly, the size and orientation of Gabor filter were self-adjusted according to local ridge's orientation and mean frequency. Finally, the poor-quality fingerprint images were enhanced. In the experiment, the improved Gabor filter has better performance for low-quality fingerprint images when compared with the traditional filtering methods.

  10. Enabling immersive simulation.

    Energy Technology Data Exchange (ETDEWEB)

    McCoy, Josh (University of California Santa Cruz, Santa Cruz, CA); Mateas, Michael (University of California Santa Cruz, Santa Cruz, CA); Hart, Derek H.; Whetzel, Jonathan; Basilico, Justin Derrick; Glickman, Matthew R.; Abbott, Robert G.

    2009-02-01

    The object of the 'Enabling Immersive Simulation for Complex Systems Analysis and Training' LDRD has been to research, design, and engineer a capability to develop simulations which (1) provide a rich, immersive interface for participation by real humans (exploiting existing high-performance game-engine technology wherever possible), and (2) can leverage Sandia's substantial investment in high-fidelity physical and cognitive models implemented in the Umbra simulation framework. We report here on these efforts. First, we describe the integration of Sandia's Umbra modular simulation framework with the open-source Delta3D game engine. Next, we report on Umbra's integration with Sandia's Cognitive Foundry, specifically to provide for learning behaviors for 'virtual teammates' directly from observed human behavior. Finally, we describe the integration of Delta3D with the ABL behavior engine, and report on research into establishing the theoretical framework that will be required to make use of tools like ABL to scale up to increasingly rich and realistic virtual characters.

  11. Liquid metal enabled microfluidics.

    Science.gov (United States)

    Khoshmanesh, Khashayar; Tang, Shi-Yang; Zhu, Jiu Yang; Schaefer, Samira; Mitchell, Arnan; Kalantar-Zadeh, Kourosh; Dickey, Michael D

    2017-03-14

    Several gallium-based liquid metal alloys are liquid at room temperature. As 'liquid', such alloys have a low viscosity and a high surface tension while as 'metal', they have high thermal and electrical conductivities, similar to mercury. However, unlike mercury, these liquid metal alloys have low toxicity and a negligible vapor pressure, rendering them much safer. In comparison to mercury, the distinguishing feature of these alloys is the rapid formation of a self-limiting atomically thin layer of gallium oxide over their surface when exposed to oxygen. This oxide layer changes many physical and chemical properties of gallium alloys, including their interfacial and rheological properties, which can be employed and modulated for various applications in microfluidics. Injecting liquid metal into microfluidic structures has been extensively used to pattern and encapsulate highly deformable and reconfigurable electronic devices including electrodes, sensors, antennas, and interconnects. Likewise, the unique features of liquid metals have been employed for fabricating miniaturized microfluidic components including pumps, valves, heaters, and electrodes. In this review, we discuss liquid metal enabled microfluidic components, and highlight their desirable attributes including simple fabrication, facile integration, stretchability, reconfigurability, and low power consumption, with promising applications for highly integrated microfluidic systems.

  12. Electrical Impedance Spectroscopy for Quality Assessment of Meat and Fish: A Review on Basic Principles, Measurement Methods, and Recent Advances

    Directory of Open Access Journals (Sweden)

    Xin Zhao

    2017-01-01

    Full Text Available Electrical impedance spectroscopy (EIS, as an effective analytical technique for electrochemical system, has shown a wide application for food quality and safety assessment recently. Individual differences of livestock cause high variation in quality of raw meat and fish and their commercialized products. Therefore, in order to obtain the definite quality information and ensure the quality of each product, a fast and on-line detection technology is demanded to be developed to monitor product processing. EIS has advantages of being fast, nondestructive, inexpensive, and easily implemented and shows potential to develop on-line detecting instrument to replace traditional methods to realize time, cost, skilled persons saving and further quality grading. This review outlines the fundamental theories and two common measurement methods of EIS applied to biological tissue, summarizes its application specifically for quality assessment of meat and fish, and discusses challenges and future trends of EIS technology applied for meat and fish quality assessment.

  13. Abbreviated epitaxial growth mode (AGM) method for reducing cost and improving quality of LEDs and lasers

    Science.gov (United States)

    Tansu, Nelson; Chan, Helen M; Vinci, Richard P; Ee, Yik-Khoon; Biser, Jeffrey

    2013-09-24

    The use of an abbreviated GaN growth mode on nano-patterned AGOG sapphire substrates, which utilizes a process of using 15 nm low temperature GaN buffer and bypassing etch-back and recovery processes during epitaxy, enables the growth of high-quality GaN template on nano-patterned AGOG sapphire. The GaN template grown on nano-patterned AGOG sapphire by employing abbreviated growth mode has two orders of magnitude lower threading dislocation density than that of conventional GaN template grown on planar sapphire. The use of abbreviated growth mode also leads to significant reduction in cost of the epitaxy. The growths and characteristics of InGaN quantum wells (QWs) light emitting diodes (LEDs) on both templates were compared. The InGaN QWs LEDs grown on the nano-patterned AGOG sapphire demonstrated at least a 24% enhancement of output power enhancement over that of LEDs grown on conventional GaN templates.

  14. Abbreviated epitaxial growth mode (AGM) method for reducing cost and improving quality of LEDs and lasers

    Energy Technology Data Exchange (ETDEWEB)

    Tansu, Nelson; Chan, Helen M; Vinci, Richard P; Ee, Yik-Khoon; Biser, Jeffrey

    2013-09-24

    The use of an abbreviated GaN growth mode on nano-patterned AGOG sapphire substrates, which utilizes a process of using 15 nm low temperature GaN buffer and bypassing etch-back and recovery processes during epitaxy, enables the growth of high-quality GaN template on nano-patterned AGOG sapphire. The GaN template grown on nano-patterned AGOG sapphire by employing abbreviated growth mode has two orders of magnitude lower threading dislocation density than that of conventional GaN template grown on planar sapphire. The use of abbreviated growth mode also leads to significant reduction in cost of the epitaxy. The growths and characteristics of InGaN quantum wells (QWs) light emitting diodes (LEDs) on both templates were compared. The InGaN QWs LEDs grown on the nano-patterned AGOG sapphire demonstrated at least a 24% enhancement of output power enhancement over that of LEDs grown on conventional GaN templates.

  15. Conceptualizing a quality of life framework for girls with Rett syndrome using qualitative methods.

    Science.gov (United States)

    Epstein, Amy; Leonard, Helen; Davis, Elise; Williams, Katrina; Reddihough, Dinah; Murphy, Nada; Whitehouse, Andrew; Downs, Jenny

    2016-03-01

    Rett syndrome is a neurodevelopmental disorder mainly affecting females and associated with a mutation on the MECP2 gene. There has been no systematic evaluation of the domains of quality of life (QOL) in Rett syndrome. The aims of this study were to explore QOL in school-aged children with Rett syndrome and compare domains with those identified in other available QOL scales. The sample comprised 21 families registered with the Australian Rett Syndrome Database whose daughter with Rett syndrome was aged 6-18 years. Semi-structured telephone interviews were conducted with each parent caregiver (19 mothers, 2 fathers) to investigate aspects of their daughter's life that were satisfying or challenging to her. Qualitative thematic analysis using a grounded theory framework was conducted, and emerging domains compared with those in two generic and three disability parent-report child QOL measures. Ten domains were identified: physical health, body pain, and discomfort, behavioral and emotional well-being, communication skills, movement and mobility, social connectedness, variety of activities, provision of targeted services, stability of daily routines, and the natural environment. The two latter domains were newly identified and each domain contained elements not represented in the comparison measures. Our data articulated important aspects of life beyond the genetic diagnosis. Existing QOL scales for children in the general population or with other disabilities did not capture the QOL of children with Rett syndrome. Our findings support the construction of a new parent-report measure to enable measurement of QOL in this group.

  16. Effect of cooling methods on hole quality in drilling of aluminium 6061-6T

    Science.gov (United States)

    Islam, M. N.; Boswell, B.

    2016-02-01

    The influence of cooling method and drilling parameters on hole production has been investigated experimentally and analytically by measuring the hole quality. A three-level, three-parameter experiment was conducted using design-of-experiment methodology. The three levels of independent input parameters were: for cooling method—flood drilling, minimum quantity lubrication (MQL) drilling and cryogenic drilling; for feed rate—0.2, 0.3 and 0.4 mm/rev; and for cutting speed—60, 75 and 100 m/min. The selected work and tool materials were aluminium 6061-6T and high speed steel (HSS), respectively. The measured output parameters were the three most widely used quality characteristics of drilled holes - diameter error, circularity and surface roughness. The results were analysed applying three methods: Pareto ANOVA, Taguchi method and traditional analysis. The findings revealed that the cooling method has a significant effect on diameter error (contribution ratio 88.27%), moderate effect on surface roughness (contribution ratio 41.74%) and relatively small effect on circularity (contribution ratio 23.64%). The best results for the dimensional accuracy and surface roughness were achieved by MQL drilling. Cryogenic drilling produced the best circularity results; however, in terms of dimensional accuracy and surface roughness it was the worst.

  17. Green Architecture Paradigm: from Urban Utopia to Modern Methods of Quality Assessment

    Directory of Open Access Journals (Sweden)

    Gintaras Stauskis

    2013-10-01

    Full Text Available Trends of environmental, social and economic development in the modern world are driving forward the theory and practice of Green Building with important role for architecture and architects. The article presents a comprehensive analysis of the Green Building doctrine and its historic background based on a review of main ideas of Green Architecture including its historic roots, as well as modern theories and practices of contemporary system of sustainability. Complex quality assessment methodologies developed in different regions of the world to evaluate environmental, social, economic and creative features of new and renovated buildings and urban complexes are analyzed in order to identify the most effective and advanced tools and methods. The importance of sustainability aspects is presented by a comparative analysis of basic features of building’s quality assessment methods originated in different countries and regions, as it reveals the structure and weight impact of different evaluation methods. The article also addresses the impact of Green Architecture theories and assessment methods on architectural practice by analyzing outstanding case studies in urban design, landscape architecture and volumetric building design.

  18. Improved first-order uncertainty method for water-quality modeling

    Science.gov (United States)

    Melching, C.S.; Anmangandla, S.

    1992-01-01

    Uncertainties are unavoidable in water-quality modeling and subsequent management decisions. Monte Carlo simulation and first-order uncertainty analysis (involving linearization at central values of the uncertain variables) have been frequently used to estimate probability distributions for water-quality model output due to their simplicity. Each method has its drawbacks: Monte Carlo simulation's is mainly computational time; and first-order analysis are mainly questions of accuracy and representativeness, especially for nonlinear systems and extreme conditions. An improved (advanced) first-order method is presented, where the linearization point varies to match the output level whose exceedance probability is sought. The advanced first-order method is tested on the Streeter-Phelps equation to estimate the probability distribution of critical dissolved-oxygen deficit and critical dissolved oxygen using two hypothetical examples from the literature. The advanced first-order method provides a close approximation of the exceedance probability for the Streeter-Phelps model output estimated by Monte Carlo simulation using less computer time - by two orders of magnitude - regardless of the probability distributions assumed for the uncertain model parameters.

  19. No-cost manual method for preparation of tissue microarrays having high quality comparable to semiautomated methods.

    Science.gov (United States)

    Foda, Abd Al-Rahman Mohammad

    2013-05-01

    Manual tissue microarray (TMA) construction had been introduced to avoid the high cost of automated and semiautomated techniques. The cheapest and simplest technique for constructing manual TMA was that of using mechanical pencil tips. This study was carried out to modify this method, aiming to raise its quality to reach that of expensive ones. Some modifications were introduced to Shebl's technique. Two conventional mechanical pencil tips of different diameters were used to construct the recipient blocks. A source of mild heat was used, and blocks were incubated at 38°C overnight. With our modifications, 3 high-density TMA blocks were constructed. We successfully performed immunostaining without substantial tissue loss. Our modifications increased the number of cores per block and improved the stability of the cores within the paraffin block. This new, modified technique is a good alternative for expensive machines in many laboratories.

  20. Assessment of air quality microsensors versus reference methods: The EuNetAir joint exercise

    Science.gov (United States)

    Borrego, C.; Costa, A. M.; Ginja, J.; Amorim, M.; Coutinho, M.; Karatzas, K.; Sioumis, Th.; Katsifarakis, N.; Konstantinidis, K.; De Vito, S.; Esposito, E.; Smith, P.; André, N.; Gérard, P.; Francis, L. A.; Castell, N.; Schneider, P.; Viana, M.; Minguillón, M. C.; Reimringer, W.; Otjes, R. P.; von Sicard, O.; Pohle, R.; Elen, B.; Suriano, D.; Pfister, V.; Prato, M.; Dipinto, S.; Penza, M.

    2016-12-01

    The 1st EuNetAir Air Quality Joint Intercomparison Exercise organized in Aveiro (Portugal) from 13th-27th October 2014, focused on the evaluation and assessment of environmental gas, particulate matter (PM) and meteorological microsensors, versus standard air quality reference methods through an experimental urban air quality monitoring campaign. The IDAD-Institute of Environment and Development Air Quality Mobile Laboratory was placed at an urban traffic location in the city centre of Aveiro to conduct continuous measurements with standard equipment and reference analysers for CO, NOx, O3, SO2, PM10, PM2.5, temperature, humidity, wind speed and direction, solar radiation and precipitation. The comparison of the sensor data generated by different microsensor-systems installed side-by-side with reference analysers, contributes to the assessment of the performance and the accuracy of microsensor-systems in a real-world context, and supports their calibration and further development. The overall performance of the sensors in terms of their statistical metrics and measurement profile indicates significant differences in the results depending on the platform and on the sensors considered. In terms of pollutants, some promising results were observed for O3 (r2: 0.12-0.77), CO (r2: 0.53-0.87), and NO2 (r2: 0.02-0.89). For PM (r2: 0.07-0.36) and SO2 (r2: 0.09-0.20) the results show a poor performance with low correlation coefficients between the reference and microsensor measurements. These field observations under specific environmental conditions suggest that the relevant microsensor platforms, if supported by the proper post processing and data modelling tools, have enormous potential for new strategies in air quality control.