WorldWideScience

Sample records for methodological quality results

  1. Social control of the quality of public services: Theory, methodology and results of empirical research

    Directory of Open Access Journals (Sweden)

    Evgeny A. Kapoguzov

    2017-06-01

    Full Text Available The article reveals the theoretical and methodological aspect of the problem of social control in relation to the possibility of its implementation in the production of public services. The interdisciplinary nature of the discourse on the nature of social control is presented, the evolution of ideas about it in the framework of social science concepts is presented, and the relationship with related categories is revealed, in particular, "public control", "civil control". The evolution of essence is also traced the category "institutionalization", it is shown the lack of unambiguousness in its interpretation. The normative value of the institutionalization of social practices in the implementation of institutional design is presented, in particular, with regard to the improvement of the provision of public services. The barriers of institutionalization of social control (resource, information, institutional for quality of public services are characterized. The results of a mass survey of consumers of public services conducted in December 2016 in the Multifunctional Center (MFC of city Omsk are presented. Unlike other surveys and publications that only assess the level of customer satisfaction and do not give a detailed explanation of the attitude of consumers to the ongoing institutional changes, this paper presents an analysis of consumer attitudes and beliefs to meaningful attributes of the quality of public services on the one hand, and for various institutional alternatives of influence on the quality of public services on the other. According to the results of the mass survey, the low readiness for social action was established due to high transaction costs, the rational ignorance and a free-rider problem. The possibility of institutionalizing the practice of social action and setting up consumers for the creation of a specialized organization for the protection of consumer rights in the production of public services was discussed.

  2. Maps of sharpness: a methodology to present results of quality control for mammographic system

    International Nuclear Information System (INIS)

    Oliveira, Henrique Jesus Quintino de; Marques, Marcio Alexandre; Frere, Annie France; Schiable, Homero; Marques, Paulo M. Azevedo; Irita, Ricardo Toshiyuki

    1996-01-01

    A new method for evaluating radiologic imaging systems quality is presented. This method intends to relate the numeric results from quality control procedures to the magnitude of shadow and penumbra in the image from given objects. This evaluation is based on a computer simulation and it can be performed for any system and any object placed in any location of the radiation field

  3. The Plumbing of Land Surface Models: Is Poor Performance a Result of Methodology or Data Quality?

    Science.gov (United States)

    Haughton, Ned; Abramowitz, Gab; Pitman, Andy J.; Or, Dani; Best, Martin J.; Johnson, Helen R.; Balsamo, Gianpaolo; Boone, Aaron; Cuntz, Matthais; Decharme, Bertrand; hide

    2016-01-01

    The PALS Land sUrface Model Benchmarking Evaluation pRoject (PLUMBER) illustrated the value of prescribing a priori performance targets in model intercomparisons. It showed that the performance of turbulent energy flux predictions from different land surface models, at a broad range of flux tower sites using common evaluation metrics, was on average worse than relatively simple empirical models. For sensible heat fluxes, all land surface models were outperformed by a linear regression against downward shortwave radiation. For latent heat flux, all land surface models were outperformed by a regression against downward shortwave, surface air temperature and relative humidity. These results are explored here in greater detail and possible causes are investigated. We examine whether particular metrics or sites unduly influence the collated results, whether results change according to time-scale aggregation and whether a lack of energy conservation in fluxtower data gives the empirical models an unfair advantage in the intercomparison. We demonstrate that energy conservation in the observational data is not responsible for these results. We also show that the partitioning between sensible and latent heat fluxes in LSMs, rather than the calculation of available energy, is the cause of the original findings. Finally, we present evidence suggesting that the nature of this partitioning problem is likely shared among all contributing LSMs. While we do not find a single candidate explanation forwhy land surface models perform poorly relative to empirical benchmarks in PLUMBER, we do exclude multiple possible explanations and provide guidance on where future research should focus.

  4. The quality of reporting methods and results of cost-effectiveness analyses in Spain: a methodological systematic review.

    Science.gov (United States)

    Catalá-López, Ferrán; Ridao, Manuel; Alonso-Arroyo, Adolfo; García-Altés, Anna; Cameron, Chris; González-Bermejo, Diana; Aleixandre-Benavent, Rafael; Bernal-Delgado, Enrique; Peiró, Salvador; Tabarés-Seisdedos, Rafael; Hutton, Brian

    2016-01-07

    Cost-effectiveness analysis has been recognized as an important tool to determine the efficiency of healthcare interventions and services. There is a need for evaluating the reporting of methods and results of cost-effectiveness analyses and establishing their validity. We describe and examine reporting characteristics of methods and results of cost-effectiveness analyses conducted in Spain during more than two decades. A methodological systematic review was conducted with the information obtained through an updated literature review in PubMed and complementary databases (e.g. Scopus, ISI Web of Science, National Health Service Economic Evaluation Database (NHS EED) and Health Technology Assessment (HTA) databases from Centre for Reviews and Dissemination (CRD), Índice Médico Español (IME) Índice Bibliográfico Español en Ciencias de la Salud (IBECS)). We identified cost-effectiveness analyses conducted in Spain that used quality-adjusted life years (QALYs) as outcome measures (period 1989-December 2014). Two reviewers independently extracted the data from each paper. The data were analysed descriptively. In total, 223 studies were included. Very few studies (10; 4.5 %) reported working from a protocol. Most studies (200; 89.7 %) were simulation models and included a median of 1000 patients. Only 105 (47.1 %) studies presented an adequate description of the characteristics of the target population. Most study interventions were categorized as therapeutic (189; 84.8 %) and nearly half (111; 49.8 %) considered an active alternative as the comparator. Effectiveness of data was derived from a single study in 87 (39.0 %) reports, and only few (40; 17.9 %) used evidence synthesis-based estimates. Few studies (42; 18.8 %) reported a full description of methods for QALY calculation. The majority of the studies (147; 65.9 %) reported that the study intervention produced "more costs and more QALYs" than the comparator. Most studies (200; 89.7 %) reported favourable

  5. Q methodology, risk training and quality management.

    Science.gov (United States)

    McKeown, M; Hinks, M; Stowell-Smith, M; Mercer, D; Forster, J

    1999-01-01

    The results of a Q methodological study of professional understandings of the notion of risk in mental health services within the UK are discussed in relation to the relevance for staff training and quality assurance. The study attempted to access the diversity of understandings of risk issues amongst a multi-professional group of staff (n = 60) attending inter-agency risk training workshops in 1998. Q methodology is presented as both an appropriate means for such inquiry and as a novel experiential technique for training purposes. A tentative argument is advanced that the qualitative accounts generated by Q research could assist in systematic reviews of quality, complementing the singularly quantitative approaches typically represented in the audit process.

  6. Intersystem LOCA risk assessment: methodology and results

    International Nuclear Information System (INIS)

    Galyean, W.J.; Kelly, D.L.; Schroeder, J.A.; Auflick, L.J.; Blackman, H.S.; Gertman, D.I.; Hanley, L.N.

    1994-01-01

    The United States Nuclear Regulatory Commission is sponsoring a research program to develop an improved understanding of the human factors, hardware and accident consequence issues that dominate the risk from an intersystem loss-of-coolant accident (ISLOCA) at a nuclear power plant. To accomplish the goals of this program, a mehtodology has been developed for estimating ISLOCA core damage frequency and risk. The steps in this methodology are briefly described, along with the results obtained from an application of the methodology at three pressurized water reactors. Also included are the results of a screening study of boiling water reactors. ((orig.))

  7. Air quality estimation by computational intelligence methodologies

    Directory of Open Access Journals (Sweden)

    Ćirić Ivan T.

    2012-01-01

    Full Text Available The subject of this study is to compare different computational intelligence methodologies based on artificial neural networks used for forecasting an air quality parameter - the emission of CO2, in the city of Niš. Firstly, inputs of the CO2 emission estimator are analyzed and their measurement is explained. It is known that the traffic is the single largest emitter of CO2 in Europe. Therefore, a proper treatment of this component of pollution is very important for precise estimation of emission levels. With this in mind, measurements of traffic frequency and CO2 concentration were carried out at critical intersections in the city, as well as the monitoring of a vehicle direction at the crossroad. Finally, based on experimental data, different soft computing estimators were developed, such as feed forward neural network, recurrent neural network, and hybrid neuro-fuzzy estimator of CO2 emission levels. Test data for some characteristic cases presented at the end of the paper shows good agreement of developed estimator outputs with experimental data. Presented results are a true indicator of the implemented method usability. [Projekat Ministarstva nauke Republike Srbije, br. III42008-2/2011: Evaluation of Energy Performances and br. TR35016/2011: Indoor Environment Quality of Educational Buildings in Serbia with Impact to Health and Research of MHD Flows around the Bodies, in the Tip Clearances and Channels and Application in the MHD Pumps Development

  8. A Methodology for Anatomic Ultrasound Image Diagnostic Quality Assessment

    DEFF Research Database (Denmark)

    Hemmsen, Martin Christian; Lange, Theis; Brandt, Andreas Hjelm

    2017-01-01

    are presented. Earlier uses of the methodology has shown that it ensures validity of the assessment, as it separates the influences between developer, investigator, and assessor once a research protocol has been established. This separation reduces confounding influences on the result from the developer......This paper discusses methods for assessment of ultrasound image quality based on our experiences with evaluating new methods for anatomic imaging. It presents a methodology to ensure a fair assessment between competing imaging methods using clinically relevant evaluations. The methodology...... to properly reveal the clinical value. The paper exemplifies the methodology using recent studies of Synthetic Aperture Sequential Beamforming tissue harmonic imaging....

  9. Methodological quality of guidelines in gastroenterology.

    Science.gov (United States)

    Malheiro, Rui; de Monteiro-Soares, Matilde; Hassan, Cesare; Dinis-Ribeiro, Mário

    2014-06-01

    Clinical guidelines are a common feature in modern endoscopy practice and they are being produced faster than ever. However, their methodological quality is rarely assessed. This study evaluated the methodological quality of current clinical guidelines in the field of gastroenterology, with an emphasis on endoscopy. Practice guidelines published by the American College of Gastroenterology (ACG), American Gastroenterological Association (AGA), American Society for Gastrointestinal Endoscopy (ASGE), European Society of Gastrointestinal Endoscopy (ESGE), British Society of Gastroenterology (BSG), National Institute for Health and Care Excellence (NICE), and the Scottish Intercollegiate Guidelines Network (SIGN) were searched between September and October 2012 and evaluated using the AGREE II (Appraisal of Guidelines for Research and Evaluation) instrument (23 items, scores 1 - 7 for each item; higher scores mean better quality). A total of 100 guidelines were assessed. The mean number of items scoring 6 or 7 per guideline was 9.2 (out of 23 items). Overall, 99 % of guidelines failed to include the target population in the development process, and 96 % did not report facilitators and barriers to guideline application. In addition, 86 % did not include advice or tools, and 94 % did not present monitoring or auditing criteria. The global methodological quality of clinical guidelines in the field of gastroenterology is poor, particularly regarding involvement of the target population in the development of guidelines and in the provision of clear suggestions to practitioners. © Georg Thieme Verlag KG Stuttgart · New York.

  10. Urbanism & urban qualities New data and methodologies

    DEFF Research Database (Denmark)

    2009-01-01

    The interest in urban spaces and their qualities has become stronger in recent years. A substantial volume of projects aims to create attractive urban spaces reasons of Sustainability, Quality of Life and urban vitality. But who actually uses the urban spaces, which urban spaces are used? How do...... they use them? What characterizes the good urban space? And how and by who is it evaluated? How is a better co-operation between urban space researchers, decision makers and users established? Is it the right urban spaces which receive investments? How can research optimize the basis for decisions......?   Proceedings from the conference "Urbanism & urban qualities - new data & methodologies" held 24th of June 2009 at The Royal Danish Academy of Fine Arts in Copenhagen....

  11. A Methodology for Quality Problems Diagnosis in SMEs

    OpenAIRE

    Humberto N. Teixeira; Isabel S. Lopes; Sérgio D. Sousa

    2012-01-01

    This article proposes a new methodology to be used by SMEs (Small and Medium enterprises) to characterize their performance in quality, highlighting weaknesses and area for improvement. The methodology aims to identify the principal causes of quality problems and help to prioritize improvement initiatives. This is a self-assessment methodology that intends to be easy to implement by companies with low maturity level in quality. The methodology is organized in six different steps which include...

  12. Methodology of quality improvement projects for the Texas Medicare population.

    Science.gov (United States)

    Pendergrass, P W; Abel, R L; Bing, M; Vaughn, R; McCauley, C

    1998-07-01

    The Texas Medical Foundation, the quality improvement organization for the state of Texas, develops local quality improvement projects for the Medicare population. These projects are developed as part of the Health Care Quality Improvement Program undertaken by the Health Care Financing Administration. The goal of a local quality improvement project is to collaborate with providers to identify and reduce the incidence of unintentional variations in the delivery of care that negatively impact outcomes. Two factors are critical to the success of a quality improvement project. First, as opposed to peer review that is based on implicit criteria, quality improvement must be based on explicit criteria. These criteria represent key steps in the delivery of care that have been shown to improve outcomes for a specific disease. Second, quality improvement must be performed in partnership with the health care community. As such, the health care community must play an integral role in the design and evaluation of a quality improvement project and in the design and implementation of the resulting quality improvement plan. Specifically, this article provides a historical perspective for the transition from peer review to quality improvement. It discusses key steps used in developing and implementing local quality improvement projects including topic selection, quality indicator development, collaborator recruitment, and measurement of performance/improvement. Two Texas Medical Foundation projects are described to highlight the current methodology and to illustrate the impact of quality improvement projects.

  13. Methodological Quality of Consensus Guidelines in Implant Dentistry.

    Science.gov (United States)

    Faggion, Clovis Mariano; Apaza, Karol; Ariza-Fritas, Tania; Málaga, Lilian; Giannakopoulos, Nikolaos Nikitas; Alarcón, Marco Antonio

    2017-01-01

    Consensus guidelines are useful to improve clinical decision making. Therefore, the methodological evaluation of these guidelines is of paramount importance. Low quality information may guide to inadequate or harmful clinical decisions. To evaluate the methodological quality of consensus guidelines published in implant dentistry using a validated methodological instrument. The six implant dentistry journals with impact factors were scrutinised for consensus guidelines related to implant dentistry. Two assessors independently selected consensus guidelines, and four assessors independently evaluated their methodological quality using the Appraisal of Guidelines for Research & Evaluation (AGREE) II instrument. Disagreements in the selection and evaluation of guidelines were resolved by consensus. First, the consensus guidelines were analysed alone. Then, systematic reviews conducted to support the guidelines were included in the analysis. Non-parametric statistics for dependent variables (Wilcoxon signed rank test) was used to compare both groups. Of 258 initially retrieved articles, 27 consensus guidelines were selected. Median scores in four domains (applicability, rigour of development, stakeholder involvement, and editorial independence), expressed as percentages of maximum possible domain scores, were below 50% (median, 26%, 30.70%, 41.70%, and 41.70%, respectively). The consensus guidelines and consensus guidelines + systematic reviews data sets could be compared for 19 guidelines, and the results showed significant improvements in all domain scores (p dentistry journals is needed. The findings of the present study may help researchers to better develop consensus guidelines in implant dentistry, which will improve the quality and trust of information needed to make proper clinical decisions.

  14. Safety on Judo Children: Methodology and Results

    OpenAIRE

    Sacripanti, Attilio; De Blasis, Tania

    2017-01-01

    Many doctors although they have not firsthand experience of judo, describe it as a sport unsuitable for children. Theoretically speaking falls derived by Judo throwing techniques,could be potentially dangerous,especially for kids,if poorly managed.A lot of researches were focalized on trauma or injuries taking place in judo, both during training and competition The goal of this Research is to define and apply a scientific methodology to evaluate the hazard in falls by judo throws for children...

  15. Quality Assurance in Trichiasis Surgery: a methodology

    Science.gov (United States)

    Buchan, John C; Limburg, Hans; Burton, Matthew J

    2013-01-01

    SUMMARY Trachoma remains a significant cause of blindness in many parts of the world. The major route to blindness involves upper lid entropion leading to trachomatous trichiasis (TT) which promotes progressive corneal opacification. The provision of surgery to correct TT in the populations most severely affected is a major challenge for the global effort to eliminate Trachoma blindness by the year 2020. Most attention has been paid to increasing the quantity of TT surgery performed, and large numbers of non-doctor operators have been trained to this end. Surgical audit by those performing TT surgery is not a routine part of any national trachoma control programme, and no effective mechanism exists for identifying surgeons experiencing poor outcomes. We propose a methodology for surgical audit at the level of the individual surgeon based on Lot Quality Assurance. A set number of patients operated on previously for upper eyelid TT are examined to detect the recurrence of TT. The number of recurrent cases found will lead to categorisation of the TT surgeon to either “high recurrence” or “low recurrence” with reasonable confidence. The threshold of unacceptability can be set by individual programmes according to previous local studies of recurrence rates or those from similar settings. Identification of surgeons delivering unacceptably high levels of recurrent TT will guide managers on the need for remedial intervention such as re-training. PMID:20881027

  16. Quality assurance in trichiasis surgery: a methodology.

    Science.gov (United States)

    Buchan, John C; Limburg, Hans; Burton, Matthew J

    2011-03-01

    Trachoma remains a significant cause of blindness in many parts of the world. The major route to blindness involves upper lid entropion leading to trachomatous trichiasis (TT), which promotes progressive corneal opacification. The provision of surgery to correct TT in the populations most severely affected is a major challenge for the global effort to eliminate trachoma blindness by the year 2020. Most attention has focused on increasing the quantity of TT surgery performed, and large numbers of non-doctor operators have been trained to this end. Surgical audit by those performing TT surgery is not a routine part of any national trachoma control programme, and no effective mechanism exists for identifying surgeons experiencing poor outcomes. The authors propose a methodology for surgical audit at the level of the individual surgeon based on Lot Quality Assurance. A set number of patients operated on previously for upper eyelid TT are examined to detect the recurrence of TT. The number of recurrent cases found will lead to categorisation of the TT surgeon to either 'high recurrence' or 'low recurrence' with reasonable confidence. The threshold of unacceptability can be set by individual programmes according to previous local studies of recurrence rates or those from similar settings. Identification of surgeons delivering unacceptably high levels of recurrent TT will guide managers on the need for remedial intervention such as retraining.

  17. Methodologies for defining quality of life

    Energy Technology Data Exchange (ETDEWEB)

    Glicken, J. [Ecological Planning and Toxicology, Inc., Albuquerque, NM (United States); Engi, D. [Sandia National Labs., Albuquerque, NM (United States)

    1996-10-10

    Quality of life as a concept has been used in many ways in the public policy arena. It can be used in summative evaluations to assess the impacts of policies or programs. Alternatively, it can be applied to formative evaluations to provide input to the formation of new policies. In short, it provides the context for the understanding needed to evaluate the results of choices that have been made in the public policy arena, or the potential of choices yet to be made. In either case, the public policy question revolves around the positive or negative impact the choice will have on quality of life, and the magnitude of that impact. This discussion will develop a conceptual framework that proposes that an assessment of quality of life is based on a comparison of expectations with experience. The framework defines four basic components from which these expectations arise: natural conditions, social conditions, the body, and the mind. Each one of these components is generally described, and associated with a general policy or rhetorical category which gives it its policy vocabulary--environmental quality, economic well-being, human health, and self-fulfillment.

  18. The ABT methodology employment for VET of quality auditors

    Directory of Open Access Journals (Sweden)

    Liviu Moldovan

    2011-12-01

    Full Text Available This paper presents some achievements of the project entitled “Disseminating Open and Innovative Tools and Services for Vocational Education and Training in Quality Assurance” (acronym Do-IT financed by European Commission. The recent developments and results obtained during pilot testing of new pedagogical models and services, in Do-IT project, targeting engineering education in Romania are presented. This include the activity Based Training methodology (ABT for quality management system audit course according to ISO 19011 and ISO 9001 and evaluation of theoretical achievements with Student Response System (SRS.

  19. A methodology model for quality management in a general hospital.

    Science.gov (United States)

    Stern, Z; Naveh, E

    1997-01-01

    A reappraisal is made of the relevance of industrial modes of quality management to the issues of medical care. Analysis of the nature of medical care, which differentiates it from the supplier-client relationships of industry, presents the main intrinsic characteristics, which create problems in application of the industrial quality management approaches to medical care. Several examples are the complexity of the relationship between the medical action and the result obtained, the client's nonacceptance of economic profitability as a value in his medical care, and customer satisfaction biased by variable standards of knowledge. The real problems unique to hospitals are addressed, and a methodology model for their quality management is offered. Included is a sample of indicator vectors, measurements of quality care, cost of medical care, quality of service, and human resources. These are based on the trilogy of planning quality, quality control, and improving quality. The conclusions confirm the inadequacy of industrial quality management approaches for medical institutions and recommend investment in formulation of appropriate concepts.

  20. Methodology for stereoscopic motion-picture quality assessment

    Science.gov (United States)

    Voronov, Alexander; Vatolin, Dmitriy; Sumin, Denis; Napadovsky, Vyacheslav; Borisov, Alexey

    2013-03-01

    Creating and processing stereoscopic video imposes additional quality requirements related to view synchronization. In this work we propose a set of algorithms for detecting typical stereoscopic-video problems, which appear owing to imprecise setup of capture equipment or incorrect postprocessing. We developed a methodology for analyzing the quality of S3D motion pictures and for revealing their most problematic scenes. We then processed 10 modern stereo films, including Avatar, Resident Evil: Afterlife and Hugo, and analyzed changes in S3D-film quality over the years. This work presents real examples of common artifacts (color and sharpness mismatch, vertical disparity and excessive horizontal disparity) in the motion pictures we processed, as well as possible solutions for each problem. Our results enable improved quality assessment during the filming and postproduction stages.

  1. Complaint studies: Methodological considerations and a result

    DEFF Research Database (Denmark)

    Juhl, Hans Jørn; Poulsen, Carsten Stig; Thøgersen, John

    The purpose of this paper is twofold. Firstly we present in a non-technical form some of the measurement problems involved in interpreting consumer complaint data and secondly we provide some empirical results based upon a complaint study carried out in Denmark in 2002. Several measurement models...... are developed, ranging from the Rasch model via latent structure analysis with several correlated latent variables to suggestions about a comprehensive framework, combining Fishbein-Ajzen's Theory of Planned Behaviour and latent trait models. The empirical results show that the propensity to complain in Denmark...

  2. Measurement of Quality of Life I. A Methodological Framework

    Directory of Open Access Journals (Sweden)

    Soren Ventegodt

    2003-01-01

    Full Text Available Despite the widespread acceptance of quality of life (QOL as the ideal guideline in healthcare and clinical research, serious conceptual and methodological problems continue to plague this area. In an attempt to remedy this situation, we propose seven criteria that a quality-of-life concept must meet to provide a sound basis for investigation by questionnaire. The seven criteria or desiderata are: (1 an explicit definition of quality of life; (2 a coherent philosophy of human life from which the definition is derived; (3 a theory that operationalizes the philosophy by specifying unambiguous, nonoverlapping, and jointly exhaustive questionnaire items; (4 response alternatives that permit a fraction-scale interpretation; (5 technical checks of reproducibility; (6 meaningfulness to investigators, respondents, and users; and (7 an overall aesthetic appeal of the questionnaire. These criteria have guided the design of a validated 5-item generic, global quality-of-life questionnaire (QOL5, and a validated 317-item generic, global quality-of-life questionnaire (SEQOL, administered to a well-documented birth cohort of 7,400 Danes born in 1959�1961, as well as to a reference sample of 2,500 Danes. Presented in outline, the underlying integrative quality-of-life (IQOL theory is a meta-theory. To illustrate the seven criteria at work, we show the extent to which they are satisfied by one of the eight component theories. Next, two sample results of our investigation are presented: satisfaction with one's sex life has the expected covariation with one's quality of life, and so does mother's smoking during pregnancy, albeit to a much smaller extent. It is concluded that the methodological framework presented has proved helpful in designing a questionnaire that is capable of yielding acceptably valid and reliable measurements of global and generic quality of life.

  3. NIF Target Assembly Metrology Methodology and Results

    Energy Technology Data Exchange (ETDEWEB)

    Alger, E. T. [General Atomics, San Diego, CA (United States); Kroll, J. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Dzenitis, E. G. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Montesanti, R. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Hughes, J. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Swisher, M. [IAP, Livermore, CA (United States); Taylor, J. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Segraves, K. [IAP, Livermore, CA (United States); Lord, D. M. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Reynolds, J. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Castro, C. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Edwards, G. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2011-01-01

    During our inertial confinement fusion (ICF) experiments at the National Ignition Facility (NIF) we require cryogenic targets at the 1-cm scale to be fabricated, assembled, and metrologized to micron-level tolerances. During assembly of these ICF targets, there are physical dimensmetrology is completed using optical coordinate measurement machines that provide repeatable measurements with micron precision, while also allowing in-process data collection for absolute accuracy in assembly. To date, 51 targets have been assembled and metrologized, and 34 targets have been successfully fielded on NIF relying on these metrology data. In the near future, ignition experiments on NIF will require tighter tolerances and more demanding target assembly and metrology capability. Metrology methods, calculations, and uncertainty estimates will be discussed. Target diagnostic port alignment, target position, and capsule location results will be reviewed for the 2009 Energetics Campaign. The information is presented via control charts showing the effect of process improvements that were made during target production. Certain parameters, including capsule position, met the 2009 campaign specifications but will have much tighter requirements in the future. Finally, in order to meet these new requirements assembly process changes and metrology capability upgrades will be necessary.

  4. Systematic review of communication partner training in aphasia: methodological quality.

    Science.gov (United States)

    Cherney, Leora R; Simmons-Mackie, Nina; Raymer, Anastasia; Armstrong, Elizabeth; Holland, Audrey

    2013-10-01

    Twenty-three studies identified from a previous systematic review examining the effects of communication partner training on persons with aphasia and their communication partners were evaluated for methodological quality. Two reviewers rated the studies on defined methodological quality criteria relevant to each study design. There were 11 group studies, seven single-subject participant design studies, and five qualitative studies. Quality scores were derived for each study. The mean inter-rater reliability of scores for each study design ranged from 85-93%, with Cohen's Kappa indicating substantial agreement between raters. Methodological quality of research on communication partner training in aphasia was highly varied. Overall, group studies employed the least rigorous methodology as compared to single subject and qualitative research. Only two of 11 group studies complied with more than half of the quality criteria. No group studies reported therapist blinding and only one group study reported participant blinding. Across all types of studies, the criterion of treatment fidelity was most commonly omitted. Failure to explicitly report certain methodological quality criteria may account for low ratings. Using methodological rating scales specific to the type of study design may help improve the methodological quality of aphasia treatment studies, including those on communication partner training.

  5. The main aspects of methodology of quality management system

    Directory of Open Access Journals (Sweden)

    Smirnova E.K.

    2017-03-01

    Full Text Available this article describes the formation and development of quality management as an integrated system. The author considers the theory and methodology of quality management since the early XXth century to the present day and describes the main problems encountered in the process of quality management system, as well as the ways to overcome them.

  6. An objective methodology for the evaluation of the air quality stations positioning

    International Nuclear Information System (INIS)

    Benassi, A.; Marson, G.; Baraldo, E.; Dalan, F.; Lorenzet, K.; Bellasio, R.; Bianconi, R.

    2006-01-01

    This work describes a methodology for the evaluation of the correct positioning of the monitoring stations of an air quality network. The methodology is based on the Italian legislation, the European Directives and on some technical documents used as guidelines at European level. The paper describes all the assumption on which the methodology is based and the results of its application to the air quality network of Region Veneto (Italy) [it

  7. OpenKnowledge Deliverable 3.3.: A methodology for ontology matching quality evaluation

    OpenAIRE

    Yatskevich, Mikalai; Giunchiglia, Fausto; McNeill, Fiona; Shvaiko, Pavel

    2007-01-01

    This document presents an evaluation methodology for the assessment of quality results produced by ontology matchers. In particular, it discusses: (i) several standard quality measures used in the ontology matching evaluation, (ii) a methodology of how to build semiautomatically an incomplete reference alignment allowing for the assessment of quality results produced by ontology matchers and (iii) a preliminary empirical evaluation of the OpenKnowledge ontology matching component.

  8. Methodology and Supporting Toolset Advancing Embedded Systems Quality

    DEFF Research Database (Denmark)

    Berger, Michael Stübert; Soler, José; Brewka, Lukasz Jerzy

    2013-01-01

    Software quality is of primary importance in the development of embedded systems that are often used in safety-critical applications. Moreover, as the life cycle of embedded products becomes increasingly tighter, productivity and quality are simultaneously required and closely interrelated towards...... delivering competitive products. In this context, the MODUS (Methodology and supporting toolset advancing embedded systems quality) project aims to provide a pragmatic and viable solution that will allow SMEs to substantially improve their positioning in the embedded-systems development market. This paper...... will describe the MODUS project with focus on the technical methodologies that will be developed advancing embedded system quality....

  9. Dynamic benchmarking methodology for Quality Function Deployment

    NARCIS (Netherlands)

    Raharjo, H.; Brombacher, A.C.; Chai, K.H.; Bergman, B.

    2008-01-01

    A competitive advantage, generally, can be gained if a firm produces a product that not only addresses what the customer values most, but also performs better than its competitors in terms of quality, cost, and timeliness. However, these two factors, namely, the customer needs and competitorspsila

  10. Methodological quality of systematic reviews on influenza vaccination.

    Science.gov (United States)

    Remschmidt, Cornelius; Wichmann, Ole; Harder, Thomas

    2014-03-26

    There is a growing body of evidence on the risks and benefits of influenza vaccination in various target groups. Systematic reviews are of particular importance for policy decisions. However, their methodological quality can vary considerably. To investigate the methodological quality of systematic reviews on influenza vaccination (efficacy, effectiveness, safety) and to identify influencing factors. A systematic literature search on systematic reviews on influenza vaccination was performed, using MEDLINE, EMBASE and three additional databases (1990-2013). Review characteristics were extracted and the methodological quality of the reviews was evaluated using the assessment of multiple systematic reviews (AMSTAR) tool. U-test, Kruskal-Wallis test, chi-square test, and multivariable linear regression analysis were used to assess the influence of review characteristics on AMSTAR-score. Fourty-six systematic reviews fulfilled the inclusion criteria. Average methodological quality was high (median AMSTAR-score: 8), but variability was large (AMSTAR range: 0-11). Quality did not differ significantly according to vaccination target group. Cochrane reviews had higher methodological quality than non-Cochrane reviews (p=0.001). Detailed analysis showed that this was due to better study selection and data extraction, inclusion of unpublished studies, and better reporting of study characteristics (all p<0.05). In the adjusted analysis, no other factor, including industry sponsorship or journal impact factor had an influence on AMSTAR score. Systematic reviews on influenza vaccination showed large differences regarding their methodological quality. Reviews conducted by the Cochrane collaboration were of higher quality than others. When using systematic reviews to guide the development of vaccination recommendations, the methodological quality of a review in addition to its content should be considered. Copyright © 2014 Elsevier Ltd. All rights reserved.

  11. Methodological quality of systematic reviews addressing femoroacetabular impingement.

    Science.gov (United States)

    Kowalczuk, Marcin; Adamich, John; Simunovic, Nicole; Farrokhyar, Forough; Ayeni, Olufemi R

    2015-09-01

    As the body of literature on femoroacetabular impingement (FAI) continues to grow, clinicians turn to systematic reviews to remain current with the best available evidence. The quality of systematic reviews in the FAI literature is currently unknown. The goal of this study was to assess the quality of the reporting of systematic reviews addressing FAI over the last 11 years (2003-2014) and to identify the specific methodological shortcomings and strengths. A search of the electronic databases, MEDLINE, EMBASE and PubMed, was performed to identify relevant systematic reviews. Methodological quality was assessed by two reviewers using the revised assessment of multiple systematic reviews (R-AMSTAR) scoring tool. An intraclass correlation coefficient (ICC) with 95 % confidence intervals (CI) was used to determine agreement between reviewers on R-AMSTAR quality scores. A total of 22 systematic reviews were assessed for methodological quality. The mean consensus R-AMSTAR score across all studies was 26.7 out of 40.0, indicating fair methodological quality. An ICC of 0.931, 95 % CI 0.843-0.971 indicated excellent agreement between reviewers during the scoring process. The systematic reviews addressing FAI are generally of fair methodological quality. Use of tools such as the R-AMSTAR score or PRISMA guidelines while designing future systematic reviews can assist in eliminating methodological shortcomings identified in this review. These shortcomings need to be kept in mind by clinicians when applying the current literature to their patient populations and making treatment decisions. Systematic reviews of highest methodological quality should be used by clinicians when possible to answer clinical questions.

  12. Measuring the Quality of Publications : New Methodology and Case Study

    NARCIS (Netherlands)

    Kleijnen, J.P.C.; van Groenendaal, W.J.H.

    2000-01-01

    n practice, it is important to evaluate the quality of research, in order to make decisions on tenure, funding, and so on. This article develops a methodology using citations to measure the quality of journals, proceedings, and book publishers. (Citations are also used by the Science and Social

  13. Quality control of CT units - methodology of performance I

    International Nuclear Information System (INIS)

    Prlic, I.; Radalj, Z.

    1996-01-01

    Increasing use of x-ray computed tomography systems (CT scanners) in the diagnostic requires an efficient means of evaluating the performance of them. Therefore, this paper presents the way to measure (Quality Control procedure-Q/C) and define the CT scanner performance through a special phantom which is based on the recommendation of the American association of Physicists in Medicine (AAPM). The performance parameters measurable with the phantom represent the capability, so periodical evaluation of the parameters enable the users to recognize the stability of the CT scanner no matter on the manufacturer, model or software option of the scanner. There are five important performance parameters which are to be measured: Noise, Contrast scale, Nominal tomographic section thickness, High and Low contrast resolution (MTF). The sixth parameter is, of course the dose per scan and slice which gives the patient dose for the certain diagnostic procedure. The last but not the least parameter is the final image quality which is given through the image processing device connected to the scanner. This is the final medical information needed for the good medical practice according to the Quality Assurance (Q/A) procedures in diagnostic radiology. We have to assure the results of the performance evaluation without environmental influences (the measurements are to be made under the certain conditions according Q/A). This paper will give no detailed methodology recipe but will show on the one example; the system noise measurements and linearity; the need and relevant results of the measurements.1 The rest of the methodology is to be published. (author)

  14. The development of a checklist to enhance methodological quality in intervention programs

    Directory of Open Access Journals (Sweden)

    Salvador Chacón-Moscoso

    2016-11-01

    Full Text Available The methodological quality of primary studies is an important issue when performing meta-analyses or systematic reviews. Nevertheless, there are no clear criteria for how methodological quality should be analyzed. Controversies emerge when considering the various theoretical and empirical definitions, especially in relation to three interrelated problems: the lack of representativeness, utility, and feasibility. In this article, we (a systematize and summarize the available literature about methodological quality in primary studies; (b propose a specific, parsimonious, 12-item checklist to empirically define the methodological quality of primary studies based on a content validity study; and (c present an inter-coder reliability study for the resulting 12 items. This paper provides a precise and rigorous description of the development of this checklist, highlighting the clearly specified criteria for the inclusion of items and a substantial inter-coder agreement in the different items. Rather than simply proposing another checklist, however, it then argues that the list constitutes an assessment tool with respect to the representativeness, utility, and feasibility of the most frequent methodological quality items in the literature, one that provides practitioners and researchers with clear criteria for choosing items that may be adequate to their needs. We propose individual methodological features as indicators of quality, arguing that these need to be taken into account when designing, implementing, or evaluating an intervention program. This enhances methodological quality of intervention programs and fosters the cumulative knowledge based on meta-analyses of these interventions. Future development of the checklist is discussed.

  15. The Statistical point of view of Quality: the Lean Six Sigma methodology.

    Science.gov (United States)

    Bertolaccini, Luca; Viti, Andrea; Terzi, Alberto

    2015-04-01

    Six Sigma and Lean are two quality improvement methodologies. The Lean Six Sigma methodology is applicable to repetitive procedures. Therefore, the use of this methodology in the health-care arena has focused mainly on areas of business operations, throughput, and case management and has focused on efficiency outcomes. After the revision of methodology, the paper presents a brief clinical example of the use of Lean Six Sigma as a quality improvement method in the reduction of the complications during and after lobectomies. Using Lean Six Sigma methodology, the multidisciplinary teams could identify multiple modifiable points across the surgical process. These process improvements could be applied to different surgical specialties and could result in a measurement, from statistical point of view, of the surgical quality.

  16. Development of Management Methodology for Engineering Production Quality

    Science.gov (United States)

    Gorlenko, O.; Miroshnikov, V.; Borbatc, N.

    2016-04-01

    The authors of the paper propose four directions of the methodology developing the quality management of engineering products that implement the requirements of new international standard ISO 9001:2015: the analysis of arrangement context taking into account stakeholders, the use of risk management, management of in-house knowledge, assessment of the enterprise activity according to the criteria of effectiveness

  17. Using Quality Tools and Methodologies to Improve a Hospital's Quality Position.

    Science.gov (United States)

    Branco, Daniel; Wicks, Angela M; Visich, John K

    2017-01-01

    The authors identify the quality tools and methodologies most frequently used by quality-positioned hospitals versus nonquality hospitals. Northeastern U.S. hospitals in both groups received a brief, 12-question survey. The authors found that 93.75% of the quality hospitals and 81.25% of the nonquality hospitals used some form of process improvement methodologies. However, there were significant differences between the groups regarding the impact of quality improvement initiatives on patients. The findings indicate that in quality hospitals the use of quality improvement initiatives had a significantly greater positive impact on patient satisfaction and patient outcomes when compared to nonquality hospitals.

  18. Organ Donation European Quality System: ODEQUS project methodology.

    Science.gov (United States)

    Manyalich, M; Guasch, X; Gomez, M P; Páez, G; Teixeira, L

    2013-01-01

    Differences in the number of organ donors among hospitals cannot be explained only by the number of intensive care unit beds used or neurologic patients treated. The figures obtained are influenced by the organizational structure of the donation process and how efficient it is. The Organ Donation European Quality System (ODEQUS) is a 3-year project (from October 2010 to September 2013) co-financed by the European Agency for Health and Consumers (EAHC20091108) which aims to define a methodology to evaluate organ procurement performance at the hospital level. ODEQUS's specific objectives are to identify quality criteria and to develop quality indicators in three types of organ donation (after brain death, after cardiac death, and living donation). Those tools will be useful for hospitals' self-assessment as well as for developing an international auditing model. A consortium has been established involving 14 associated partners from Austria, Croatia, France, Germany, Italy, Poland, Portugal, Romania, Spain, Sweden, and the United Kingdom, as well as five collaborating partners from Greece, Hungary, Malta, Slovenia, and Turkey. The project has been established in three steps: 1) Design of a survey about the use of quality tools in a wide sample of European hospitals; 2) Development of quality criteria and quality indicators by the project experts. The main fields considered have been organizational structures, clinical procedures, and outcomes; and 3) Elaboration of an evaluation system to test the quality indicators in 11 European hospitals. Two types of training have been designed and performed: one concerns the development of quality criteria and quality indicators, whereas another is focused on how to use evaluation tools. Following this methodology, the project has so far identified 131 quality criteria and developed 31 quality indicators. Currently, the quality indicators are being tested in 11 selected hospitals. Copyright © 2013 Elsevier Inc. All rights

  19. ASSESSMENT OF QUALITY OF LIFE: PRESENT AND FUTURE METHODOLOGICAL CHALLENGES

    Directory of Open Access Journals (Sweden)

    Isabel Benítez

    2016-01-01

    Full Text Available The growing importance of quality of life in diverse domains, such as health, school performance and social participation, has led to the development of new conceptualisations and assessments of the construct. This diversity of perspectives brings about many benefits, but it also creates an obstacle for the formulation of a single unifying definition of the construct and, therefore, an agreed instrument or assessment framework. The aim of this study is to discuss the current methodological challenges in the measurement of quality of life. Firstly, we provide a brief description of the construct as defined in various areas, then we examine the new methodological developments and different applications. We also present an overview of the different possibilities for future developments in defining and measuring quality of life in national and international studies.

  20. A Quality-Driven Methodology for Information Systems Integration

    Directory of Open Access Journals (Sweden)

    Iyad Zikra

    2017-10-01

    Full Text Available Information systems integration is an essential instrument for organizations to attain advantage in today’s growing and fast changing business and technology landscapes. Integration solutions generate added value by combining the functionality and services of heterogeneous and diverse systems. Existing integration environments tend to rely heavily on technical, platform-dependent skills. Consequently, the solutions that they enable are not optimally aligned with the envisioned business goals of the organization. Furthermore, the gap between the goals and the solutions complicates the task of evaluating the quality of integration solutions. To address these challenges, we propose a quality-driven, model-driven methodology for designing and developing integration solutions. The methodology spans organizational and systems design details, providing a holistic view of the integration solution and its underlying business goals. A multi-view meta-model provides the basis for the integration design. Quality factors that affect various aspects of the integration solution guide and inform the progress of the methodology. An example business case is presented to demonstrate the application of the methodology.

  1. Methodology of clinical measures of healthcare quality delivered to patients with cardiovascular diseases

    Directory of Open Access Journals (Sweden)

    Posnenkova O.M.

    2014-03-01

    Full Text Available The results of implementation the methodology proposed by American Colleague of Cardiology and American Heart Association (ACC/AHA for development of Russian clinical quality measures for patients with arterial hypertension, coronary heart disease and chronic heart failure. Created quality measures cover the key elements of medical care influencing directly on clinical outcomes of treatment.

  2. QUALITY IMPROVEMENT IN MULTIRESPONSE EXPERIMENTS THROUGH ROBUST DESIGN METHODOLOGY

    Directory of Open Access Journals (Sweden)

    M. Shilpa

    2012-06-01

    Full Text Available Robust design methodology aims at reducing the variability in the product performance in the presence of noise factors. Experiments involving simultaneous optimization of more than one quality characteristic are known as multiresponse experiments which are used in the development and improvement of industrial processes and products. In this paper, robust design methodology is applied to optimize the process parameters during a particular operation of rotary driving shaft manufacturing process. The three important quality characteristics of the shaft considered here are of type Nominal-the-best, Smaller-the-better and Fraction defective. Simultaneous optimization of these responses is carried out by identifying the control parameters and conducting the experimentation using L9 orthogonal array.

  3. Methodology for Multileaf Collimator Quality Assurance in clinical conditions

    International Nuclear Information System (INIS)

    Diaz M, R. M.; Rodriguez Z, M.; Juarez D, A.; Romero R, R.

    2013-01-01

    Multileaf Collimators (MLCs) have become an important technological advance as part of clinical linear accelerators (linacs) for radiotherapy. Treatment planning and delivery were substantially modified after these devices. However, it was needed to develop Quality Assurance (QA) methodologies related to the performance of these developments. The most common methods for QA of MLC are made in basic conditions that hardly cover all possible difficulties in clinical practice. Diaz et. el. developed a methodology based upon volumetric detectors bidimensional arrays that can be extended to more demanding situations. In this work, the Auril methodology of Diaz et. al. was implemented to the irradiation with the linac gantry in horizontal position. A mathematical procedure was developed to ease the dosimetric centering of the device with the Auril centering tool. System calibration was made as in the typical Auril methodology. Patterns with leaf misplacements in known positions were irradiated. the method allowed the detection of leafs' misplacements with a minimum number of false positives. We concluded that Auril methodology can be applied in clinical conditions. (Author)

  4. Annual report on electricity quality - 2013 results

    International Nuclear Information System (INIS)

    2014-01-01

    Every year, RTE, The French transmission system operator, evaluates the electricity quality of the French grid. Quality covers two aspects: the continuity of supply (percentage of outages) and the voltage wave quality (temporary or continuous disturbances). This report presents: the 2013 key figures and highlights, RTE's electricity quality commitments, RTE's technical results and quality assurance, and RTE's action for grid performances improvement

  5. Annual report on electricity quality - 2008 results

    International Nuclear Information System (INIS)

    2009-01-01

    Every year, RTE, The French transmission system operator, evaluates the electricity quality of the French grid. Quality covers two aspects: the continuity of supply (percentage of outages) and the voltage wave quality (temporary or continuous disturbances). This report presents: the 2008 key figures and highlights, RTE's electricity quality commitments, RTE's technical results and quality assurance, and RTE's action for grid performances improvement

  6. Annual report on electricity quality - 2009 results

    International Nuclear Information System (INIS)

    2010-01-01

    Every year, RTE, The French transmission system operator, evaluates the electricity quality of the French grid. Quality covers two aspects: the continuity of supply (percentage of outages) and the voltage wave quality (temporary or continuous disturbances). This report presents: the 2009 key figures and highlights, RTE's electricity quality commitments, RTE's technical results and quality assurance, and RTE's action for grid performances improvement

  7. Annual report on electricity quality - 2011 results

    International Nuclear Information System (INIS)

    2012-01-01

    Every year, RTE, The French transmission system operator, evaluates the electricity quality of the French grid. Quality covers two aspects: the continuity of supply (percentage of outages) and the voltage wave quality (temporary or continuous disturbances). This report presents: the 2011 key figures and highlights, RTE's electricity quality commitments, RTE's technical results and quality assurance, and RTE's action for grid performances improvement

  8. Annual report on electricity quality - 2016 results

    International Nuclear Information System (INIS)

    2016-01-01

    Every year, RTE, The French transmission system operator, evaluates the electricity quality of the French grid. Quality covers two aspects: the continuity of supply (percentage of outages) and the voltage wave quality (temporary or continuous disturbances). This report presents: the 2016 key figures and highlights, RTE's electricity quality commitments, RTE's technical results and quality assurance, and RTE's action for grid performances improvement

  9. Annual report on electricity quality - 2014 results

    International Nuclear Information System (INIS)

    2015-01-01

    Every year, RTE, The French transmission system operator, evaluates the electricity quality of the French grid. Quality covers two aspects: the continuity of supply (percentage of outages) and the voltage wave quality (temporary or continuous disturbances). This report presents: the 2014 key figures and highlights, RTE's electricity quality commitments, RTE's technical results and quality assurance, and RTE's action for grid performances improvement

  10. Annual report on electricity quality - 2015 results

    International Nuclear Information System (INIS)

    2016-01-01

    Every year, RTE, The French transmission system operator, evaluates the electricity quality of the French grid. Quality covers two aspects: the continuity of supply (percentage of outages) and the voltage wave quality (temporary or continuous disturbances). This report presents: the 2015 key figures and highlights, RTE's electricity quality commitments, RTE's technical results and quality assurance, and RTE's action for grid performances improvement

  11. Annual report on electricity quality - 2012 results

    International Nuclear Information System (INIS)

    2013-01-01

    Every year, RTE, the French transmission system operator, evaluates the electricity quality of the French grid. Quality covers two aspects: the continuity of supply (percentage of outages) and the voltage wave quality (temporary or continuous disturbances). This report presents: the 2012 key figures and highlights, RTE's electricity quality commitments, RTE's technical results and quality assurance, and RTE's action for grid performances improvement

  12. Annual report on electricity quality - 2010 results

    International Nuclear Information System (INIS)

    2011-01-01

    Every year, RTE, The French transmission system operator, evaluates the electricity quality of the French grid. Quality covers two aspects: the continuity of supply (percentage of outages) and the voltage wave quality (temporary or continuous disturbances). This report presents: the 2010 key figures and highlights, RTE's electricity quality commitments, RTE's technical results and quality assurance, and RTE's action for grid performances improvement

  13. Methodological Quality Assessment of Meta-analyses in Endodontics.

    Science.gov (United States)

    Kattan, Sereen; Lee, Su-Min; Kohli, Meetu R; Setzer, Frank C; Karabucak, Bekir

    2018-01-01

    The objectives of this review were to assess the methodological quality of published meta-analyses related to endodontics using the assessment of multiple systematic reviews (AMSTAR) tool and to provide a follow-up to previously published reviews. Three electronic databases were searched for eligible studies according to the inclusion and exclusion criteria: Embase via Ovid, The Cochrane Library, and Scopus. The electronic search was amended by a hand search of 6 dental journals (International Endodontic Journal; Journal of Endodontics; Australian Endodontic Journal; Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology; Endodontics and Dental Traumatology; and Journal of Dental Research). The searches were conducted to include articles published after July 2009, and the deadline for inclusion of the meta-analyses was November 30, 2016. The AMSTAR assessment tool was used to evaluate the methodological quality of all included studies. A total of 36 reports of meta-analyses were included. The overall quality of the meta-analyses reports was found to be medium, with an estimated mean overall AMSTAR score of 7.25 (95% confidence interval, 6.59-7.90). The most poorly assessed areas were providing an a priori design, the assessment of the status of publication, and publication bias. In recent publications in the field of endodontics, the overall quality of the reported meta-analyses is medium according to AMSTAR. Copyright © 2017 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

  14. Methodology of quality control for brachytherapy {sup 125}I seeds

    Energy Technology Data Exchange (ETDEWEB)

    Moura, Eduardo S.; Zeituni, Carlos A.; Manzoli, Jose E.; Rostelato, Maria Elisa C.M. [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)]. E-mail: esmoura@ipen.br

    2007-07-01

    This paper presents the methodology of quality control of {sup 125}I seeds used for brachytherapy. The {sup 125}I seeds are millimeter titanium capsules widely used in permanent implants of prostate cancer, allowing a high dose within the tumour and a low dose on the surrounding tissues, with very low harm to the other tissues. Besides, with this procedure, the patients have a low impotence rate and a small incidence of urinary incontinence. To meet the medical standards, an efficient quality control is necessary, showing values with the minimum uncertainness possible, concerning the seeds dimensions and their respective activities. The medical needles are used to insert the seeds inside the prostate. The needles used in brachytherapy have an internal diameter of 1.0 mm, so it is necessary {sup 125}I seeds with an external maximum diameter of 0.85 mm. For the seeds and the spacer positioning on the planning sheet, the seeds must have a length between 4.5 and 5.0 mm. The activities must not vary more than 5% in each batch of {sup 125}I seeds. For this methodology, we used two ionization chamber detectors and one caliper. In this paper, the methodology using one control batch with 75 seeds manufactured by GE Health care Ltd is presented. (author)

  15. Methodology and Results of Mathematical Modelling of Complex Technological Processes

    Science.gov (United States)

    Mokrova, Nataliya V.

    2018-03-01

    The methodology of system analysis allows us to draw a mathematical model of the complex technological process. The mathematical description of the plasma-chemical process was proposed. The importance the quenching rate and initial temperature decrease time was confirmed for producing the maximum amount of the target product. The results of numerical integration of the system of differential equations can be used to describe reagent concentrations, plasma jet rate and temperature in order to achieve optimal mode of hardening. Such models are applicable both for solving control problems and predicting future states of sophisticated technological systems.

  16. METHODOLOGY OF AN ASSESSMENT OF RESULTS OF INTELLECTUAL ACTIVITY

    Directory of Open Access Journals (Sweden)

    Larisa I. Egorova

    2013-01-01

    Full Text Available The methodological bases of an assessment of the results of research, development and technological works and intangible assets are given in the article. A special attention is paid to the problems of formation of fair value of such assets for clients of financial accounting. The authors compare the methods of cost measurement of accounting entities regulated by Russian Accounting Standards (RAS and International Financial Reporting Standards (IFRS. Peculiarities of detection and acknowledgement of impairment of intangible assets (loss of value are considered.

  17. The relationship between return on investment and quality of study methodology in workplace health promotion programs.

    Science.gov (United States)

    Baxter, Siyan; Sanderson, Kristy; Venn, Alison J; Blizzard, C Leigh; Palmer, Andrew J

    2014-01-01

    To determine the relationship between return on investment (ROI) and quality of study methodology in workplace health promotion programs. Data were obtained through a systematic literature search of National Health Service Economic Evaluation Database (NHS EED), Database of Abstracts of Reviews of Effects (DARE), Health Technology Database (HTA), Cost Effectiveness Analysis (CEA) Registry, EconLit, PubMed, Embase, Wiley, and Scopus. Included were articles written in English or German reporting cost(s) and benefit(s) and single or multicomponent health promotion programs on working adults. Return-to-work and workplace injury prevention studies were excluded. Methodological quality was graded using British Medical Journal Economic Evaluation Working Party checklist. Economic outcomes were presented as ROI. ROI was calculated as ROI = (benefits - costs of program)/costs of program. Results were weighted by study size and combined using meta-analysis techniques. Sensitivity analysis was performed using two additional methodological quality checklists. The influences of quality score and important study characteristics on ROI were explored. Fifty-one studies (61 intervention arms) published between 1984 and 2012 included 261,901 participants and 122,242 controls from nine industry types across 12 countries. Methodological quality scores were highly correlated between checklists (r = .84-.93). Methodological quality improved over time. Overall weighted ROI [mean ± standard deviation (confidence interval)] was 1.38 ± 1.97 (1.38-1.39), which indicated a 138% return on investment. When accounting for methodological quality, an inverse relationship to ROI was found. High-quality studies (n = 18) had a smaller mean ROI, 0.26 ± 1.74 (.23-.30), compared to moderate (n = 16) 0.90 ± 1.25 (.90-.91) and low-quality (n = 27) 2.32 ± 2.14 (2.30-2.33) studies. Randomized control trials (RCTs) (n = 12) exhibited negative ROI, -0.22 ± 2.41(-.27 to -.16). Financial returns become

  18. A quality evaluation methodology of health web-pages for non-professionals.

    Science.gov (United States)

    Currò, Vincenzo; Buonuomo, Paola Sabrina; Onesimo, Roberta; de Rose, Paola; Vituzzi, Andrea; di Tanna, Gian Luca; D'Atri, Alessandro

    2004-06-01

    The proposal of an evaluation methodology for determining the quality of healthcare web sites for the dissemination of medical information to non-professionals. Three (macro) factors are considered for the quality evaluation: medical contents, accountability of the authors, and usability of the web site. Starting from two results in the literature the problem of whether or not to introduce a weighting function has been investigated. This methodology has been validated on a specialized information content, i.e., sore throats, due to the large interest such a topic enjoys with target users. The World Wide Web was accessed using a meta-search system merging several search engines. A statistical analysis was made to compare the proposed methodology with the obtained ranks of the sample web pages. The statistical analysis confirms that the variables examined (per item and sub factor) show substantially similar ranks and are capable of contributing to the evaluation of the main quality macro factors. A comparison between the aggregation functions in the proposed methodology (non-weighted averages) and the weighting functions, derived from the literature, allowed us to verify the suitability of the method. The proposed methodology suggests a simple approach which can quickly award an overall quality score for medical web sites oriented to non-professionals.

  19. Survey of the prevalence and methodology of quality assurance for B-mode ultrasound image quality among veterinary sonographers.

    Science.gov (United States)

    Hoscheit, Larry P; Heng, Hock Gan; Lim, Chee Kin; Weng, Hsin-Yi

    2018-05-01

    Image quality in B-mode ultrasound is important as it reflects the diagnostic accuracy and diagnostic information provided during clinical scanning. Quality assurance programs for B-mode ultrasound systems/components are comprised of initial quality acceptance testing and subsequent regularly scheduled quality control testing. The importance of quality assurance programs for B-mode ultrasound image quality using ultrasound phantoms is well documented in the human medical and medical physics literature. The purpose of this prospective, cross-sectional, survey study was to determine the prevalence and methodology of quality acceptance testing and quality control testing of image quality for ultrasound system/components among veterinary sonographers. An online electronic survey was sent to 1497 members of veterinary imaging organizations: the American College of Veterinary Radiology, the Veterinary Ultrasound Society, and the European Association of Veterinary Diagnostic Imaging, and a total of 167 responses were received. The results showed that the percentages of veterinary sonographers performing quality acceptance testing and quality control testing are 42% (64/151; 95% confidence interval 34-52%) and 26% (40/156: 95% confidence interval 19-33%) respectively. Of the respondents who claimed to have quality acceptance testing or quality control testing of image quality in place for their ultrasound system/components, 0% have performed quality acceptance testing or quality control testing correctly (quality acceptance testing 95% confidence interval: 0-6%, quality control testing 95% confidence interval: 0-11%). Further education and guidelines are recommended for veterinary sonographers in the area of quality acceptance testing and quality control testing for B-mode ultrasound equipment/components. © 2018 American College of Veterinary Radiology.

  20. SR-Site groundwater flow modelling methodology, setup and results

    International Nuclear Information System (INIS)

    Selroos, Jan-Olof; Follin, Sven

    2010-12-01

    As a part of the license application for a final repository for spent nuclear fuel at Forsmark, the Swedish Nuclear Fuel and Waste Management Company (SKB) has undertaken three groundwater flow modelling studies. These are performed within the SR-Site project and represent time periods with different climate conditions. The simulations carried out contribute to the overall evaluation of the repository design and long-term radiological safety. Three time periods are addressed; the Excavation and operational phases, the Initial period of temperate climate after closure, and the Remaining part of the reference glacial cycle. The present report is a synthesis of the background reports describing the modelling methodology, setup, and results. It is the primary reference for the conclusions drawn in a SR-Site specific context concerning groundwater flow during the three climate periods. These conclusions are not necessarily provided explicitly in the background reports, but are based on the results provided in these reports. The main results and comparisons presented in the present report are summarised in the SR-Site Main report

  1. SR-Site groundwater flow modelling methodology, setup and results

    Energy Technology Data Exchange (ETDEWEB)

    Selroos, Jan-Olof (Swedish Nuclear Fuel and Waste Management Co., Stockholm (Sweden)); Follin, Sven (SF GeoLogic AB, Taeby (Sweden))

    2010-12-15

    As a part of the license application for a final repository for spent nuclear fuel at Forsmark, the Swedish Nuclear Fuel and Waste Management Company (SKB) has undertaken three groundwater flow modelling studies. These are performed within the SR-Site project and represent time periods with different climate conditions. The simulations carried out contribute to the overall evaluation of the repository design and long-term radiological safety. Three time periods are addressed; the Excavation and operational phases, the Initial period of temperate climate after closure, and the Remaining part of the reference glacial cycle. The present report is a synthesis of the background reports describing the modelling methodology, setup, and results. It is the primary reference for the conclusions drawn in a SR-Site specific context concerning groundwater flow during the three climate periods. These conclusions are not necessarily provided explicitly in the background reports, but are based on the results provided in these reports. The main results and comparisons presented in the present report are summarised in the SR-Site Main report.

  2. Relationships between abstract features and methodological quality explained variations of social media activity derived from systematic reviews about psoriasis interventions.

    Science.gov (United States)

    Ruano, J; Aguilar-Luque, M; Isla-Tejera, B; Alcalde-Mellado, P; Gay-Mimbrera, J; Hernandez-Romero, José Luis; Sanz-Cabanillas, J L; Maestre-López, B; González-Padilla, M; Carmona-Fernández, P J; Gómez-García, F; García-Nieto, A Vélez

    2018-05-24

    The aim of this study was to describe the relationship among abstract structure, readability, and completeness, and how these features may influence social media activity and bibliometric results, considering systematic reviews (SRs) about interventions in psoriasis classified by methodological quality. Systematic literature searches about psoriasis interventions were undertaken on relevant databases. For each review, methodological quality was evaluated using the Assessing the Methodological Quality of Systematic Reviews (AMSTAR) tool. Abstract extension, structure, readability, and quality and completeness of reporting were analyzed. Social media activity, which consider Twitter and Facebook mention counts, as well as Mendeley readers and Google scholar citations were obtained for each article. Analyses were conducted to describe any potential influence of abstract characteristics on review's social media diffusion. We classified 139 intervention SRs as displaying high/moderate/low methodological quality. We observed that abstract readability of SRs has been maintained high for last 20 years, although there are some differences based on their methodological quality. Free-format abstracts were most sensitive to the increase of text readability as compared with more structured abstracts (IMRAD or 8-headings), yielding opposite effects on their quality and completeness depending on the methodological quality: a worsening in low quality reviews and an improvement in those of high-quality. Both readability indices and PRISMA for Abstract total scores showed an inverse relationship with social media activity and bibliometric results in high methodological quality reviews but not in those of lower quality. Our results suggest that increasing abstract readability must be specially considered when writing free-format summaries of high-quality reviews, because this fact correlates with an improvement of their completeness and quality, and this may help to achieve broader

  3. Hydrologic testing methodology and results from deep basalt boreholes

    International Nuclear Information System (INIS)

    Strait, S.R.; Spane, F.A.; Jackson, R.L.; Pidcoe, W.W.

    1982-05-01

    The objective of the hydrologic field-testing program is to provide data for characterization of the groundwater systems wihin the Pasco Basin that are significant to understanding waste isolation. The effort is directed toward characterizing the areal and vertical distributions of hydraulic head, hydraulic properties, and hydrochemistry. Data obtained from these studies provide input for numerical modeling of groundwater flow and solute transport. These models are then used for evaluating potential waste migration as a function of space and time. The groundwater system beneath the Hanford Site and surrounding area consists of a thick, accordantly layered sequence of basalt flows and associated sedimentary interbed that primarily occur in the upper part of the Columbia River basalt. Permeable horizons of the sequence are associated with the interbeds and the interflow zones within the basalt. The columnar interiors of a flow act as low-permeability aquitards, separating the more-permeable interflows or interbeds. This paper discusses the hydrologic field-gathering activities, specifically, field-testing methodology and test results from deep basalt boreholes

  4. The HCV Synthesis Project: Scope, methodology, and preliminary results

    Directory of Open Access Journals (Sweden)

    Scheinmann Roberta

    2008-09-01

    Full Text Available Abstract Background The hepatitis C virus (HCV is hyper-endemic in injecting drug users. There is also excess HCV among non-injection drug users who smoke, snort, or sniff heroin, cocaine, crack, or methamphetamine. Methods To summarize the research literature on HCV in drug users and identify gaps in knowledge, we conducted a synthesis of the relevant research carried out between 1989 and 2006. Using rigorous search methods, we identified and extracted data from published and unpublished reports of HCV among drug users. We designed a quality assurance system to ensure accuracy and consistency in all phases of the project. We also created a set of items to assess study design quality in each of the reports we included. Results We identified 629 reports containing HCV prevalence rates, incidence rates and/or genotype distribution among injecting or non-injecting drug user populations published between January 1989 and December 2006. The majority of reports were from Western Europe (41%, North America (26%, Asia (11% and Australia/New Zealand (10%. We also identified reports from Eastern Europe, South America, the Middle East, and the Caribbean. The number of publications reporting HCV rates in drug users increased dramatically between 1989 and 2006 to 27–52 reports per year after 1998. Conclusion The data collection and quality assurance phases of the HCV Synthesis Project have been completed. Recommendations for future research on HCV in drug users have come out of our data collection phase. Future research reports can enhance their contributions to our understanding of HCV etiology by clearly defining their drug user participants with respect to type of drug and route of administration. Further, the use of standard reporting methods for risk factors would enable data to be combined across a larger set of studies; this is especially important for HCV seroconversion studies which suffer from small sample sizes and low power to examine risk

  5. Development of Management Quality Assessment Methodology in the Public Sector: Problems and Contradictions

    Directory of Open Access Journals (Sweden)

    Olga Vladimirovna Kozhevina

    2015-09-01

    Full Text Available The development management quality assessment methodology in the public sector is relevant scientific and practical problem of economic research. The utilization of the results of the assessment on the basis of the authors’ methodology allows us to rate the public sector organizations, to justify decisions on the reorganization and privatization, and to monitor changes in the level of the management quality of the public sector organizations. The study determined the place of the quality of the control processes of the public sector organization in the system of “Quality of public administration — the effective operation of the public sector organization,” the contradictions associated with the assessment of management quality are revealed, the conditions for effective functioning of the public sector organizations are proved, a mechanism of comprehensive assessment and algorithm for constructing and evaluating the control models of management quality are developed, the criteria for assessing the management quality in the public sector organizations, including economic, budgetary, social and public, informational, innovation and institutional criteria are empirically grounded. By utilizing the proposed algorithm, the assessment model of quality management in the public sector organizations, including the financial, economic, social, innovation, informational and institutional indicators is developed. For each indicator of quality management, the coefficients of importance in the management quality assessment model, as well as comprehensive and partial evaluation indicators are determined on the basis of the expert evaluations. The main conclusion of the article is that management quality assessment for the public sector organizations should be based not only on the indicators achieved in the dynamics and utilized for analyzing the effectiveness of management, but also should take into account the reference levels for the values of these

  6. Reporting and methodologic quality of Cochrane Neonatal review group systematic reviews

    Directory of Open Access Journals (Sweden)

    Al Faleh Khalid

    2009-06-01

    Full Text Available Abstract Background The Cochrane Neonatal Review Group (CNRG has achieved a lot with limited resources in producing high quality systematic reviews to assist clinicians in evidence-based decision-making. A formal assessment of published CNRG systematic reviews has not been undertaken; we sought to provide a comprehensive assessment of the quality of systematic reviews (both methodologic and reporting quality published in CNRG. Methods We selected a random sample of published CNRG systematic reviews. Items of the QUOROM statement were utilized to assess quality of reporting, while items and total scores of the Oxman-Guyatt Overview Quality Assessment Questionnaire (OQAQ were used to assess methodologic quality. Two reviewers independently extracted data and assessed quality. A Student t-test was used to compare quality scores pre- and post-publication of the QUOROM statement. Results Sixty-one systematic reviews were assessed. Overall, the included reviews had good quality with minor flaws based on OQAQ total scores (mean, 4.5 [0.9]; 95% CI, 4.27–4.77. However, room for improvement was noted in some areas, such as the title, abstract reporting, a priori plan for heterogeneity assessment and how to handle heterogeneity in case it exists, and assessment of publication bias. In addition, reporting of agreement among reviewers, documentation of trials flow, and discussion of possible biases were addressed in the review process. Reviews published post the QUOROM statement had a significantly higher quality scores. Conclusion The systematic reviews published in the CNRG are generally of good quality with minor flaws. However, efforts should be made to improve the quality of reports. Readers must continue to assess the quality of published reports on an individual basis prior to implementing the recommendations.

  7. Research on quality assurance classification methodology for domestic AP1000 nuclear power projects

    International Nuclear Information System (INIS)

    Bai Jinhua; Jiang Huijie; Li Jingyan

    2012-01-01

    To meet the quality assurance classification requirements of domestic nuclear safety codes and standards, this paper analyzes the quality assurance classification methodology of domestic AP1000 nuclear power projects at present, and proposes the quality assurance classification methodology for subsequent AP1000 nuclear power projects. (authors)

  8. Landscape Forsmark - data, methodology and results for SR-Site

    International Nuclear Information System (INIS)

    Lindborg, Tobias

    2010-12-01

    This report presents an integrated description of the landscape at the Forsmark site during the succession from present conditions to the far future. It was produced as a part of the biosphere modelling within the SR-Site safety assessment. The report gives a description of input data, methodology and resulting models used to support the current understanding of the landscape used in SR-Site. It is intended to describe the properties and conditions at the site and to give information essential for demonstrating understanding. The report relies heavily on a number of discipline-specific background reports concerning details of the data analyses and modelling. Long-term landscape development in the Forsmark area is dependent on two main and partly interdependent factors, i.e. climate variations and shoreline displacement. These two factors in combination strongly affect a number of processes, which in turn determine the development of ecosystems. Some examples of such processes are erosion and sedimentation, groundwater recharge and discharge, soil formation, primary production and decomposition of organic matter. The biosphere at the site during the next 1,000 years is assumed to be quite similar to the present situation. The most important changes are the natural infilling of lakes and a slight withdrawal of the sea with its effects on the near-shore areas and the shallow coastal basins. The climate during the rest of the temperate period may vary considerably, with both warmer and colder periods. The main effect of temperature changes will be on the vegetation period. Changed temperatures may give rise to drier or wetter climate and to changed snow cover and frost characteristics, and this can in turn affect the dominant vegetation and mire build-up. The description of the Forsmark ecosystem succession during a glacial cycle is one of the main features of the SR-Site biosphere modelling. The future areas potentially affected by deep groundwater discharge are

  9. Landscape Forsmark - data, methodology and results for SR-Site

    Energy Technology Data Exchange (ETDEWEB)

    Lindborg, Tobias [ed.; Svensk Kaernbraenslehantering AB (Sweden)

    2010-12-15

    This report presents an integrated description of the landscape at the Forsmark site during the succession from present conditions to the far future. It was produced as a part of the biosphere modelling within the SR-Site safety assessment. The report gives a description of input data, methodology and resulting models used to support the current understanding of the landscape used in SR-Site. It is intended to describe the properties and conditions at the site and to give information essential for demonstrating understanding. The report relies heavily on a number of discipline-specific background reports concerning details of the data analyses and modelling. Long-term landscape development in the Forsmark area is dependent on two main and partly interdependent factors, i.e. climate variations and shoreline displacement. These two factors in combination strongly affect a number of processes, which in turn determine the development of ecosystems. Some examples of such processes are erosion and sedimentation, groundwater recharge and discharge, soil formation, primary production and decomposition of organic matter. The biosphere at the site during the next 1,000 years is assumed to be quite similar to the present situation. The most important changes are the natural infilling of lakes and a slight withdrawal of the sea with its effects on the near-shore areas and the shallow coastal basins. The climate during the rest of the temperate period may vary considerably, with both warmer and colder periods. The main effect of temperature changes will be on the vegetation period. Changed temperatures may give rise to drier or wetter climate and to changed snow cover and frost characteristics, and this can in turn affect the dominant vegetation and mire build-up. The description of the Forsmark ecosystem succession during a glacial cycle is one of the main features of the SR-Site biosphere modelling. The future areas potentially affected by deep groundwater discharge are

  10. Application of quality improvement analytic methodology in emergency medicine research: A comparative evaluation.

    Science.gov (United States)

    Harries, Bruce; Filiatrault, Lyne; Abu-Laban, Riyad B

    2018-05-30

    Quality improvement (QI) analytic methodology is rarely encountered in the emergency medicine literature. We sought to comparatively apply QI design and analysis techniques to an existing data set, and discuss these techniques as an alternative to standard research methodology for evaluating a change in a process of care. We used data from a previously published randomized controlled trial on triage-nurse initiated radiography using the Ottawa ankle rules (OAR). QI analytic tools were applied to the data set from this study and evaluated comparatively against the original standard research methodology. The original study concluded that triage nurse-initiated radiographs led to a statistically significant decrease in mean emergency department length of stay. Using QI analytic methodology, we applied control charts and interpreted the results using established methods that preserved the time sequence of the data. This analysis found a compelling signal of a positive treatment effect that would have been identified after the enrolment of 58% of the original study sample, and in the 6th month of this 11-month study. Our comparative analysis demonstrates some of the potential benefits of QI analytic methodology. We found that had this approach been used in the original study, insights regarding the benefits of nurse-initiated radiography using the OAR would have been achieved earlier, and thus potentially at a lower cost. In situations where the overarching aim is to accelerate implementation of practice improvement to benefit future patients, we believe that increased consideration should be given to the use of QI analytic methodology.

  11. Proposal of a methodology for quality control in thermoluminescent dosimetry laboratory

    International Nuclear Information System (INIS)

    Feital, Joao Carlos da S.; Almeida, Claudio Domingues de; Bezerra, Marcos A.

    2005-01-01

    Taken into account that in thermoluminescence dosimetry adequate selection procedures as well as accurate TLD readings are necessary, this paper presents results of methodology that can be applied as part of quality control programs in thermoluminescence dosimetry laboratories. For the experiment, a set of 200 TLDs ( LiF 100 ) were used and 9 from which were selected, a standard source of Cs -137 , a PTW kiln, a TL 'Harshaw' reader - model 5500 operating under the 'Win Rem' software and a Sr 90 / Y 90 'Bicron' irradiator. In the proceeding the selected dosimeters were irradiated and read 28 times during 18 months, then by one of the standard deviation properties, values up to 14 % were found, for a confidence level of 95 %. The results found and the bibliographic data related to the responses (arbitrary reading) in the crystals used in TLDs, have shown that this methodology can be applied in quality control programs. (author)

  12. Report on Use of a Methodology for Commissioning and Quality Assurance of a VMAT System

    OpenAIRE

    Mayo, Charles; Fong de los Santos, Luis; Kruse, Jon; Blackwell, Charles R.; McLemore, Luke B.; Pafundi, Deanna; Stoker, Joshua; Herman, Michael

    2013-01-01

    INTRODUCTION: Results of use of methodology for VMAT commissioning and quality assurance, utilizing both control point tests and dosimetric measurements are presented. METHODS AND MATERIALS: A generalizable, phantom measurement approach is used to characterize the accuracy of the measurement system. Correction for angular response of the measurement system and inclusion of couch structures are used to characterize the full range gantry angles desirable for clinical plans. A dose based daily Q...

  13. Methodological quality of systematic reviews analyzing the use of laser therapy in restorative dentistry.

    Science.gov (United States)

    Salmos, Janaina; Gerbi, Marleny E M M; Braz, Rodivan; Andrade, Emanuel S S; Vasconcelos, Belmiro C E; Bessa-Nogueira, Ricardo V

    2010-01-01

    The purpose of this study was to identify systematic reviews (SRs) that compared laser with other dental restorative procedures and to evaluate their methodological quality. A search strategy was developed and implemented for MEDLINE, the Cochrane Library, LILACS, and the Brazilian Dentistry Bibliography (1966- 2007). Inclusion criteria were: the article had to be an SR (+/- meta-analysis); primary focus was the use of laser in restorative dentistry; published in English, Spanish, Portuguese, Italian, German. Two investigators independently selected and evaluated the SRs. The overview quality assessment questionnaire (OQAQ) was used to evaluate methodological quality, and the results were averaged. There were 145 references identified, of which seven were SRs that met the inclusion criteria (kappa=0.81). Of the SRs, 71.4% appraised lasers in dental caries diagnosis. The mean overall OQAQ score was 4.4 [95% confidence interval (CI) 2.4- 6.5]. Of the SRs, 57.1% had major flaws, scoring methodological quality is low; therefore, clinicians should critically appraise them prior to considering their recommendations to guide patient care.

  14. Applying Statistical Process Quality Control Methodology to Educational Settings.

    Science.gov (United States)

    Blumberg, Carol Joyce

    A subset of Statistical Process Control (SPC) methodology known as Control Charting is introduced. SPC methodology is a collection of graphical and inferential statistics techniques used to study the progress of phenomena over time. The types of control charts covered are the null X (mean), R (Range), X (individual observations), MR (moving…

  15. Economic evaluations of occupational health interventions from a corporate perspective - A systematic review of methodological quality

    NARCIS (Netherlands)

    Uegaki, K.; Bruijne, M.C. de; Lambeek, L.; Anema, J.R.; Beek, A.J. van der; Mechelen, W. van; Tulder, M.W. van

    2010-01-01

    Objective: Using a standardized quality criteria list, we appraised the methodological quality of economic evaluations of occupational safety and health (OSH) interventions conducted from a corporate perspective. Methods: The primary literature search was conducted in Medline and Embase.

  16. Methodological quality and scientific impact of quantitative nursing education research over 18 months.

    Science.gov (United States)

    Yucha, Carolyn B; Schneider, Barbara St Pierre; Smyer, Tish; Kowalski, Susan; Stowers, Eva

    2011-01-01

    The methodological quality of nursing education research has not been rigorously studied. The purpose of this study was to evaluate the methodological quality and scientific impact of nursing education research reports. The methodological quality of 133 quantitative nursing education research articles published between July 2006 and December 2007 was evaluated using the Medical Education Research Study Quality Instrument (MERSQI).The mean (+/- SD) MERSQI score was 9.8 +/- 2.2. It correlated (p nursing literature and those reported for the medical literature, coupled with the association with citation counts, suggest that the MERSQI is an appropriate instrument to evaluate the quality of nursing education research.

  17. The economic valuation of environmental quality: A methodological study

    International Nuclear Information System (INIS)

    Sung Yucsheng.

    1991-01-01

    Conducted in the context of sportfishing, this study uses Michigan data to estimate fishing demand and resulting consumer surplus accruing from environmental-policy implementation. For the modeling of fish-species and site decisions, a nested multinomial logit model is employed. On a pre-determined choice occasion during which a trip of a specific duration will be taken, an angler is assumed first to make a fish-species decision, then choose a site. The seasonal-participation decision is modeled by a competing-risks stochastic renewal process, incorporating time-varying parameters to account for changes in site quality through time. Since the number of trips would most likely change after a potential site-quality improvement, the proposed seasonal compensating variation (CV) calculation takes into account (1) the CV associated with the trips that would have been taken before the quality improvement, and (2) the CV associated with the new trips. The approach proposed in this study is applied to two real world policy scenarios: The termination of the Ludington Pumped Storage plant operation, and the removal of PCB contamination in the Kalamazoo River. The compensating variation is derived for both applications

  18. The implementation of the Quality Costs Methodology in the Public Transport Enterprise in Macedonia

    Directory of Open Access Journals (Sweden)

    Elizabeta Mitreva

    2017-02-01

    Full Text Available The implementation of TQM (Total Quality Management strategy in the public transport enterprises in Macedonia means improving the quality of services through examination of business processes not just in terms of defining, improvement and design of the process, but also improvement of productivity and optimization of the costs of quality. The purpose of this study is to point out the importance of determining the quality of the transport services, its methods, and techniques for measurement of the optimization of business processes in particular. The analysis of the quality costs when providing transport services can help managers to understand the impact of poor quality on the financial results and the bad image it gives to the enterprise. In this study, we proposed and applied the model for better performance and higher efficiency of the transport enterprise, through the optimization of business processes, change in the corporate culture and use of the complete business potentials. The need for this methodology was imposed as a result of the analysis made in the company in terms of whether is it doing an analysis on the costs of quality or not. The benefits from the utilization of this model will not only lead to increasing the business performance of the transport enterprise, but this model will also serve as a driving force for continuous improvements to the satisfaction of all stakeholders.

  19. Evaluation methodology based on physical security assessment results: a utility theory approach

    International Nuclear Information System (INIS)

    Bennett, H.A.; Olascoaga, M.T.

    1978-03-01

    This report describes an evaluation methodology which aggregates physical security assessment results for nuclear facilities into an overall measure of adequacy. This methodology utilizes utility theory and conforms to a hierarchical structure developed by the NRC. Implementation of the methodology is illustrated by several examples. Recommendations for improvements in the evaluation process are given

  20. Dosimetric quality control in radiotherapy using TLD methodology

    International Nuclear Information System (INIS)

    Saravi, M.C.; Kessler, C.; Alvarez, P.E.; Feld, D.B.

    2002-01-01

    In the frame of the IAEA Co-ordinated Research Project 'Development of a Quality Assurance Program for Radiation Therapy Dosimetry in Developing Countries' a Dosimetric Quality Control Group was set up in Argentina in 1996, to develop a program in order to improve radiotherapy in the country. Nowadays, this Group, briefly called External Audit Group (EAG), is composed by the national Secondary Standard Dosimetry Laboratory (SSDL), which has the responsibility for dose determinations, traceability to international dosimetry chain and TLD measurements, and two Medical Physicists from CNEA who are working at the Oncology Hospital 'Marie Curie' in Buenos Aires. The present paper reports the activities performed by the EAG with external high energy photon beams in reference conditions and the results of two pilot studies on cobalt 60 beams in non-reference conditions. The first step of the program was to update the existing data base about the radiotherapy centres operating in the country. A form was sent to each of them in order to obtain basic information about their staff, number and type of treatment machines, brachytherapy sources, measuring devices, beam calibration, treatment planning system, simulator and other relevant data. 90 radiotherapy centres were registered in the EAG data base. Forms were completed by 75/90 centres. There are nowadays 69 cobalt 60 units and 42 LINACs operating in the country (18/42 LINACs producing high energy X ray and electron beams). EAG deals with measurements performed with mailed TLD irradiated at radiotherapy centres. Internal quality control on our TLD system is made during each audit by means of reference capsules irradiated by IAEA; external controls consist in blind tests performed by IAEA once a year. The correction factor, K en , determined at our SSDL for high energy X-rays was checked with the collaboration of IAEA and Prague National Radiation Protection Institute (PNRPI) by means of a blind test. Results for 4 MV, 6 MV

  1. Systematic Review of the Methodology Quality in Lung Cancer Screening Guidelines

    Directory of Open Access Journals (Sweden)

    Jiang LI

    2016-10-01

    Full Text Available Background and objective Lung cancer is the most common malignancy and screening can decrease the mortality. High quality screening guideline is necessary and important for effective work. Our study is to review and evaluate the basic characteristics and methodology quality of the current global lung cancer screening guidelines so as to provide useful information for domestic study in the future. Methods Electronic searches were done in English and Chinese databases including PubMed, the Cochrane Library, Web of Science, Embase, CNKI, CBM, Wanfang, and some cancer official websites. Articles were screened according to the predefined inclusion and exclusion criteria by two researchers. The quality of guidelines was assessed by AGREE II. Results At last, a total of 11 guidelines with methodology were included. The guidelines were issued mainly by USA (81%. Canada and China developed one, respectively. As for quality, the average score in the “Scale and objective” of all guidelines was 80, the average score in the “Participants” was 52, the average score in the “rigorism” was 50, the average score in the “clarity” was 76, the average score in the “application” was 43 and the average score in the “independence” was 59. The highest average score was found in 2013 and 2015. Canada guideline had higher quality in six domains. 7 guidelines were evaluated as A level. Conclusion The number of clinical guidelines showed an increasing trend. Most guidelines were issued by developed countries with heavy burden. Multi-country contribution to one guideline was another trend. Evidence-based methodology was accepted globally in the guideline development.

  2. Development of a methodology for automated assessment of the quality of digitized images in mammography

    International Nuclear Information System (INIS)

    Santana, Priscila do Carmo

    2010-01-01

    The process of evaluating the quality of radiographic images in general, and mammography in particular, can be much more accurate, practical and fast with the help of computer analysis tools. The purpose of this study is to develop a computational methodology to automate the process of assessing the quality of mammography images through techniques of digital imaging processing (PDI), using an existing image processing environment (ImageJ). With the application of PDI techniques was possible to extract geometric and radiometric characteristics of the images evaluated. The evaluated parameters include spatial resolution, high-contrast detail, low contrast threshold, linear detail of low contrast, tumor masses, contrast ratio and background optical density. The results obtained by this method were compared with the results presented in the visual evaluations performed by the Health Surveillance of Minas Gerais. Through this comparison was possible to demonstrate that the automated methodology is presented as a promising alternative for the reduction or elimination of existing subjectivity in the visual assessment methodology currently in use. (author)

  3. Factor Analysis in Assessing the Research Methodology Quality of Systematic Reviews

    Directory of Open Access Journals (Sweden)

    Andrada Elena URDA-CÎMPEAN

    2011-12-01

    Full Text Available Introduction: Many high quality systematic reviews available from medical journals, data bases and other electronic sources differ in quality and provide different answers to the same question. The literature recommended the use of a checklist type approach, which exceeds many of the problems associated with measurements. Aim: This study proposes to identify in a checklist type approach the most commonly used factors (from a methodological point of view in assessing the quality of systematic reviews, and then mirror the actual stage of medical writing. We want to analyze the factors’ occurrence and / or their development in the text and in the abstract of systematic reviews published in 2011. Methods: The present study randomly selected only free full text systematic reviews published in 2011, systematic reviews found in Pubmed and in Cochrane Database. The most commonly used factors were identified in PRISMA statement and quality measurement tools. Results: The evaluated systematic reviews mentioned or developed several of the factors studied. Only 78% of the papers surveyed have used the correct IMRAD format and 59% of them have mentioned the sample size used. The correspondence between the content of the paper and its abstract is summarized in the proportion of 54.63% and 51.85% for the two sets of factors, and it can lead to scarce appreciation of the article provided that only abstracts are read. Conclusions: Researchers do not properly take into consideration scientific articles and assessment tools used for quality evaluation. They should place more value over methodological factors which help assess systematic review quality, while journals form the only party who can enforce quality standards in medical writing.

  4. Methodology for oversizing marginal quality riprap for erosion control at uranium mill tailings sites

    International Nuclear Information System (INIS)

    Staub, W.P.; Abt, S.R.

    1987-01-01

    Properly selected and oversized local sources of riprap may provide superior erosion protection compared with revegetation at a number of uranium mill tailings sites in arid regions of the United States. Whereas highly durable rock is appropriate for protecting diversion channels to the height of the 5-year flood, marginal quality rock may be adequate for protecting infrequently flooded side slopes of diversion channels, tailings embankments and caps. Marginal quality rock may require oversizing to guarantee that design size specifications are met at the end of the performance period (200 to 1000 years). This paper discusses a methodology for oversizing marginal quality rock. Results of cyclic freezing and thawing tests are used to determine oversizing requirements as functions of the performance period and environment. Test results show that marginal quality rock may be used in frequently saturated areas but in some cases oversizing will be substantial and in other cases marginal quality rock may be disqualified. Oversizing of marginal quality rock appears to be a practical reality in occasionally saturated areas (between the 5-year and 100-year floods). Furthermore, oversizing will not generally be required on slopes from the 100-year flood. 6 refs., 4 tabs

  5. Abstract analysis method facilitates filtering low-methodological quality and high-bias risk systematic reviews on psoriasis interventions.

    Science.gov (United States)

    Gómez-García, Francisco; Ruano, Juan; Aguilar-Luque, Macarena; Alcalde-Mellado, Patricia; Gay-Mimbrera, Jesús; Hernández-Romero, José Luis; Sanz-Cabanillas, Juan Luis; Maestre-López, Beatriz; González-Padilla, Marcelino; Carmona-Fernández, Pedro J; García-Nieto, Antonio Vélez; Isla-Tejera, Beatriz

    2017-12-29

    total PRISMA-A score methodological quality. Abstracts with a total PRISMA-A score ≥ 9, including main outcomes results and explanation bias risk assessment method were classified as having low-bias risk. The methodological quality and bias risk of SRs may be determined by abstract's quality and completeness analyses. Our proposal aimed to facilitate synthesis of evidence evaluation by clinical professionals lacking methodological skills. External validation is necessary.

  6. METHODOLOGY OF DETERMINATION OF QUALITY INDEX OF MAINTENANCE SERVICE SYSTEM OF POWER EQUIPMENT OF TRACTION SUBSTATIONS

    Directory of Open Access Journals (Sweden)

    O.O. Matusevych

    2016-03-01

    Full Text Available Purpose. The purpose of this paper is development of methodology for definition of a quality system of maintenance and repair (M and P power equipment of traction substations (TS of electrified railways operating under conditions of uncertainty based on expert information. Methodology. The basic tenets of the theory of fuzzy sets and marks, linguistic and interval estimates of experts were applied to solve this problem. Results. Analysis of the existing diversity of approaches to development of modern methods of improvement of M and P allows us to conclude that the improvement in the quality of the system is achieved by solving individual problems increase the operational reliability of power equipment of traction substations in the following main interrelated areas. There are technical, economic and organizational. The basis of the quality evaluation system is initial data and expertise developed version of the document formalized quality evaluation of electrical equipment of traction substations by experts. The choice of determining the level of Quality service system based on the marks, linguistic and interval estimates of experts, which are reflected in quantitative and / or qualitative form was done. The possible options for expert data presentation and their corresponding quantitative methods of calculating the integral index of quality improvement system maintenance and P of traction substations were described. The methodology and the method of assessing the quality of system maintenance and P of TS allows quickly respond to changing operating conditions of power equipment of traction substations, and to determine the most effective strategies for maintenance of electrical and P TS under conditions of uncertainty functioning distance electricity. Originality. The method of a systematic approach to improve the quality of the system maintenance and P of power equipment of traction substation under conditions of uncertainty based on expert

  7. Probabilistic safety analysis for FRJ-2 motivation, methodology and results

    International Nuclear Information System (INIS)

    Wolters, J.

    1993-01-01

    A PSA of the Research Reactor FRJ-2 was performed to check the twenty-year-old safety system for weak points and to develop accident management as a 'fourth line of defence' against severe accidents according to a German initiative. The total core damage frequency proved to be 1.5·10 -4 /a, which is consistent with figures found for other research reactors. Minor plant modifications will reduce the value by roughly a factor of 4, resulting in a frequency of 3·10 -7 /a for a major release of fission products into the environment caused by an independent failure of the containment. The integrity of the gas-tight steel containment proved not to be endangered by any core damage accident. From the results and insights gained by the PSA, many accident management measures could be identified and defined for the emergency handbook. The most important measure is primary feed and bleed, for which the feed line already exists. (author)

  8. Probabilistic safety analysis for FRJ-2 motivation, methodology and results

    Energy Technology Data Exchange (ETDEWEB)

    Wolters, J [Institute for Safety Research and Reactor Technology, Research Center Juelich (Germany)

    1993-07-01

    A PSA of the Research Reactor FRJ-2 was performed to check the twenty-year-old safety system for weak points and to develop accident management as a 'fourth line of defence' against severe accidents according to a German initiative. The total core damage frequency proved to be 1.5{center_dot}10{sup -4}/a, which is consistent with figures found for other research reactors. Minor plant modifications will reduce the value by roughly a factor of 4, resulting in a frequency of 3{center_dot}10{sup -7}/a for a major release of fission products into the environment caused by an independent failure of the containment. The integrity of the gas-tight steel containment proved not to be endangered by any core damage accident. From the results and insights gained by the PSA, many accident management measures could be identified and defined for the emergency handbook. The most important measure is primary feed and bleed, for which the feed line already exists. (author)

  9. Probabilistic safety analysis for FRJ-2 motivation, methodology and results

    International Nuclear Information System (INIS)

    Wolters, J.

    1994-01-01

    A PSA of the Research Reactor FRJ-2 was performed to check the twenty-year-old safety system for weak points and to develop accident management as a 'fourth line of defence' against severe accidents according to a German initiative. The total core damage frequency proved to be 1.5·10 -4 /a, which is consistent with figures found for other research reactors. Minor plant modifications will reduce the value by roughly a factor of 4, resulting in a frequency of 3·10 -7 /a for a major release of fission products into the environment caused by an independent failure of the containment. The integrity of the gas-tight steel containment proved not to be endangered by any core damage accident. From the results and insights gained by the PSA, many accident management measures could be identified and defined for the emergency handbook. The most important measure is primary feed and bleed, for which the feed line already exists. (author)

  10. Methodology for Evaluating Quality and Reusability of Learning Objects

    Science.gov (United States)

    Kurilovas, Eugenijus; Bireniene, Virginija; Serikoviene, Silvija

    2011-01-01

    The aim of the paper is to present the scientific model and several methods for the expert evaluation of quality of learning objects (LOs) paying especial attention to LOs reusability level. The activities of eQNet Quality Network for a European Learning Resource Exchange (LRE) aimed to improve reusability of LOs of European Schoolnet's LRE…

  11. Dictionary quality and dictionary design: a methodology for ...

    African Journals Online (AJOL)

    Although recent dictionaries for the ESL market have been praised for their innovative design features, the prime concern of users, lexicographers and metalexicographers is the functional quality of the dictionary products provided for the market. The functional quality of dictionaries and the scientific assessment thereof ...

  12. South African uranium resources - 1997 assessment methodology and results

    International Nuclear Information System (INIS)

    Ainslie, L.C.

    2001-01-01

    The first commercial uranium production in South Africa started in 1953 to meet the demand for British/US nuclear weapons. This early production reached its peak in 1959 and began to decline with the reduced demand. The world oil crisis in the 1970s sparked a second resurgence of increased uranium production that peaked in 1980 to over 6,000 tonnes. Poor market condition allied with increasing political isolation resulted in uranium production declining to less than a third of the levels achieved in the early 1980s. South Africa is well endowed with uranium resource. Its uranium resources in the RAR and EAR-I categories, extractable at costs of less than $80/kg U, as of 1 January 1997, are estimated to 284 400 tonnes U. Nearly two thirds of these resources are associated with the gold deposits in the Witwatersrand conglomerates. Most of the remaining resources occur in the Karoo sandstone and coal deposits. (author)

  13. Seismic hazard analysis. Application of methodology, results, and sensitivity studies

    International Nuclear Information System (INIS)

    Bernreuter, D.L.

    1981-10-01

    As part of the Site Specific Spectra Project, this report seeks to identify the sources of and minimize uncertainty in estimates of seismic hazards in the Eastern United States. Findings are being used by the Nuclear Regulatory Commission to develop a synthesis among various methods that can be used in evaluating seismic hazard at the various plants in the Eastern United States. In this volume, one of a five-volume series, we discuss the application of the probabilistic approach using expert opinion. The seismic hazard is developed at nine sites in the Central and Northeastern United States, and both individual experts' and synthesis results are obtained. We also discuss and evaluate the ground motion models used to develop the seismic hazard at the various sites, analyzing extensive sensitivity studies to determine the important parameters and the significance of uncertainty in them. Comparisons are made between probabilistic and real spectra for a number of Eastern earthquakes. The uncertainty in the real spectra is examined as a function of the key earthquake source parameters. In our opinion, the single most important conclusion of this study is that the use of expert opinion to supplement the sparse data available on Eastern United States earthquakes is a viable approach for determining estimated seismic hazard in this region of the country. (author)

  14. Census in a rural area of Ethiopia: methodology and results.

    Science.gov (United States)

    Materia, E; Mehari, W; Mele, A; Rosmini, F; Stazi, M A; Damen, H M; Basile, G; Kifle, T; Miuccio, G; Ferrigno, L

    1993-01-01

    A census and an ecologic survey were performed in 39 villages of a rural district of Arsi Region, Ethiopia, in difficult field circumstances. Information on age, ethnic group, education and family relationship, as well as data on health facilities and availability of basic services were collected. Supervised students, working in teams, were used as interviewers. Communities were involved through plenary meetings and community health agents participated in the data collection process. A total of 64,714 people in 12,152 households were registered. The repeatability of age assessment was investigated by comparing the results from two villages with data obtained in a pilot study carried out 6 months earlier. The technical error was only 0.80 and 1.67 in the 0-5 and 6-15 age-groups, respectively. Three percent of the total population was under one year, less than previously estimated. This may, in part, be due to the family planning programme in the region. Eighteen percent of the households were headed by females. School attendance was less common among females and in the Oromo ethnic group. The availability of basic services, including safe water and basic sanitation supplies, was very poor in the area.

  15. Quality Improvement Methodologies Increase Autologous Blood Product Administration

    Science.gov (United States)

    Hodge, Ashley B.; Preston, Thomas J.; Fitch, Jill A.; Harrison, Sheilah K.; Hersey, Diane K.; Nicol, Kathleen K.; Naguib, Aymen N.; McConnell, Patrick I.; Galantowicz, Mark

    2014-01-01

    Abstract: Whole blood from the heart–lung (bypass) machine may be processed through a cell salvaging device (i.e., cell saver [CS]) and subsequently administered to the patient during cardiac surgery. It was determined at our institution that CS volume was being discarded. A multidisciplinary team consisting of anesthesiologists, perfusionists, intensive care physicians, quality improvement (QI) professionals, and bedside nurses met to determine the challenges surrounding autologous blood delivery in its entirety. A review of cardiac surgery patients’ charts (n = 21) was conducted for analysis of CS waste. After identification of practices that were leading to CS waste, interventions were designed and implemented. Fishbone diagram, key driver diagram, Plan–Do–Study–Act (PDSA) cycles, and data collection forms were used throughout this QI process to track and guide progress regarding CS waste. Of patients under 6 kg (n = 5), 80% had wasted CS blood before interventions, whereas those patients larger than 36 kg (n = 8) had 25% wasted CS before interventions. Seventy-five percent of patients under 6 kg who had wasted CS blood received packed red blood cell transfusions in the cardiothoracic intensive care unit within 24 hours of their operation. After data collection and didactic education sessions (PDSA Cycle I), CS blood volume waste was reduced to 5% in all patients. Identification and analysis of the root cause followed by implementation of education, training, and management of change (PDSA Cycle II) resulted in successful use of 100% of all CS blood volume. PMID:24783313

  16. A food quality management research methodology integrating technological and managerial theories

    NARCIS (Netherlands)

    Luning, P.A.; Marcelis, W.J.

    2009-01-01

    In this article it is argued how the complexity of food quality management combined with the high requirements on food quality requires a specific research methodology. It is concluded that food quality management research has to deal with two quite different paradigms, the one from technological

  17. Presentation of a methodology for measuring social acceptance of three hydrogen storage technologies and preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Noirot, I.; Bigay, C. N.

    2005-07-01

    Hydrogen storage is a key technology for the extensive use of H2 as energy carrier. As none of the current technologies satisfies all of the hydrogen storage attributes required by manufacturers and end users, there is intense research works aiming at developing viable solutions. A broad objective of the StorHy European project is to provide technological storage solutions, which are attractive from an economical, environmental and safety point of view. A specific sub-project is dedicated to the comparison of three different potential storage technologies for transport applications (compressed gas, cryogenic liquid, solid media). This evaluation is carried out in a harmonised way, based on common tools and assessment strategies that could be useful for decision makers and stakeholders. The assessment is achieved in a 'sustainable development' spirit, taking into consideration the technical, environmental, economical, safety and social requirements. The latter ones have newly emerged in such evaluations, based on the Quality Function Deployment (QFD) approach, and would require to be further studied. Hydrogen acceptability studies have been conducted in previous projects. They have been reviewed by LBST in the AcceptH2 project Public acceptance of Hydrogen Transport Technologies : Analysis and comparisons of existing studies (www. accepth2. com - August 2003). During these hydrogen acceptance surveys, mainly fuel cell bus passengers from demonstration projects around the world have been questioned. The work presented in this paper goes further in the methodology refinement as it focuses on the evaluation of hydrogen storage solutions. It proposes a methodological tool for efficient social evaluation of new technologies and associated preliminary results concerning France. In a global approach to sustainable development, the CEA has developed a new methodology to evaluate its current research projects : Multicriteria Analysis for Sustainable Industrial

  18. Methodology for Air Quality Forecast Downscaling from Regional- to Street-Scale

    Science.gov (United States)

    Baklanov, Alexander; Nuterman, Roman; Mahura, Alexander; Amstrup, Bjarne; Hansen Saas, Bent; Havskov Sørensen, Jens; Lorenzen, Thomas; Weismann, Jakob

    2010-05-01

    The most serious air pollution events occur in cities where there is a combination of high population density and air pollution, e.g. from vehicles. The pollutants can lead to serious human health problems, including asthma, irritation of the lungs, bronchitis, pneumonia, decreased resistance to respiratory infections, and premature death. In particular air pollution is associated with increase in cardiovascular disease and lung cancer. In 2000 WHO estimated that between 2.5 % and 11 % of total annual deaths are caused by exposure to air pollution. However, European-scale air quality models are not suited for local forecasts, as their grid-cell is typically of the order of 5 to 10km and they generally lack detailed representation of urban effects. Two suites are used in the framework of the EC FP7 project MACC (Monitoring of Atmosphere Composition and Climate) to demonstrate how downscaling from the European MACC ensemble to local-scale air quality forecast will be carried out: one will illustrate capabilities for the city of Copenhagen (Denmark); the second will focus on the city of Bucharest (Romania). This work is devoted to the first suite, where methodological aspects of downscaling from regional (European/ Denmark) to urban scale (Copenhagen), and from the urban down to street scale. The first results of downscaling according to the proposed methodology are presented. The potential for downscaling of European air quality forecasts by operating urban and street-level forecast models is evaluated. This will bring a strong support for continuous improvement of the regional forecast modelling systems for air quality in Europe, and underline clear perspectives for the future regional air quality core and downstream services for end-users. At the end of the MACC project, requirements on "how-to-do" downscaling of European air-quality forecasts to the city and street levels with different approaches will be formulated.

  19. THE QUALITY IMPROVEMENT OF PRIMER PACKAGING PROCESS USING SIX SIGMA METHODOLOGY

    Directory of Open Access Journals (Sweden)

    Prima Ditahardiyani

    2008-01-01

    Full Text Available The implementation of Six Sigma has become a common theme in many organizations. This paper presents the Six Sigma methodology and its implementation in a primer packaging process of Cranberry drink. DMAIC (Define, Measure, Analyze, Improve and Control approach is used to analyze and to improve the primer packaging process, which have high variability and defects output. After the improvement, the results showed that there was an increasing sigma level. However, it is not significantly and has not achieved the world standard quality, yet. Therefore, the implementation of Six Sigma in primer packaging process of Cranberry drink still has a room for doing a further research.

  20. The methodological quality of systematic reviews comparing temporomandibular joint disorder surgical and non-surgical treatment

    Directory of Open Access Journals (Sweden)

    Vasconcelos Belmiro CE

    2008-09-01

    Full Text Available Abstract Background Temporomandibular joint disorders (TMJD are multifactor, complex clinical problems affecting approximately 60–70% of the general population, with considerable controversy about the most effective treatment. For example, reports claim success rates of 70% and 83% for non-surgical and surgical treatment, whereas other reports claim success rates of 40% to 70% for self-improvement without treatment. Therefore, the purpose of this study was to (1 identify systematic reviews comparing temporomandibular joint disorder surgical and non-surgical treatment, (2 evaluate their methodological quality, and (3 evaluate the evidence grade within the systematic reviews. Methods A search strategy was developed and implemented for MEDLINE, Cochrane Library, LILACS, and Brazilian Dentistry Bibliography databases. Inclusion criteria were: systematic reviews (± meta-analysis comparing surgical and non-surgical TMJD treatment, published in English, Spanish, Portuguese, Italian, or German between the years 1966 and 2007(up to July. Exclusion criteria were: in vitro or animal studies; narrative reviews or editorials or editorial letters; and articles published in other languages. Two investigators independently selected and evaluated systematic reviews. Three different instruments (AMSTAR, OQAQ and CASP were used to evaluate methodological quality, and the results averaged. The GRADE instrument was used to evaluate the evidence grade within the reviews. Results The search strategy identified 211 reports; of which 2 were systematic reviews meeting inclusion criteria. The first review met 23.5 ± 6.0% and the second met 77.5 ± 12.8% of the methodological quality criteria (mean ± sd. In these systematic reviews between 9 and 15% of the trials were graded as high quality, and 2 and 8% of the total number of patients were involved in these studies. Conclusion The results indicate that in spite of the widespread impact of TMJD, and the multitude of

  1. Improving the Quality of Experience Journals: Training Educational Psychology Students in Basic Qualitative Methodology

    Science.gov (United States)

    Reynolds-Keefer, Laura

    2010-01-01

    This study evaluates the impact of teaching basic qualitative methodology to preservice teachers enrolled in an educational psychology course in the quality of observation journals. Preservice teachers enrolled in an educational psychology course requiring 45 hr of field experience were given qualitative methodological training as a part of the…

  2. Methodological and reporting quality in laboratory studies of human eating behavior

    NARCIS (Netherlands)

    Robinson, E.; Bevelander, K.E.; Field, M.; Jones, A.

    2018-01-01

    The methodological quality and reporting practices of laboratory studies of human eating behavior determine the validity and replicability of nutrition science. The aim of this research was to examine basic methodology and reporting practices in recent representative laboratory studies of human

  3. Automatic ECG quality scoring methodology: mimicking human annotators

    International Nuclear Information System (INIS)

    Johannesen, Lars; Galeotti, Loriano

    2012-01-01

    An algorithm to determine the quality of electrocardiograms (ECGs) can enable inexperienced nurses and paramedics to record ECGs of sufficient diagnostic quality. Previously, we proposed an algorithm for determining if ECG recordings are of acceptable quality, which was entered in the PhysioNet Challenge 2011. In the present work, we propose an improved two-step algorithm, which first rejects ECGs with macroscopic errors (signal absent, large voltage shifts or saturation) and subsequently quantifies the noise (baseline, powerline or muscular noise) on a continuous scale. The performance of the improved algorithm was evaluated using the PhysioNet Challenge database (1500 ECGs rated by humans for signal quality). We achieved a classification accuracy of 92.3% on the training set and 90.0% on the test set. The improved algorithm is capable of detecting ECGs with macroscopic errors and giving the user a score of the overall quality. This allows the user to assess the degree of noise and decide if it is acceptable depending on the purpose of the recording. (paper)

  4. Economic evaluation studies in reproductive medicine: a systematic review of methodologic quality

    NARCIS (Netherlands)

    Moolenaar, Lobke M.; Vijgen, Sylvia M. C.; Hompes, Peter; van der Veen, Fulco; Mol, Ben Willem J.; Opmeer, Brent C.

    2013-01-01

    To evaluate the methodologic quality of economic analyses published in the field of reproductive medicine. Systematic review. Centers for reproductive care. Infertility patients. We performed a Medline search to identify economic evaluation studies in reproductive medicine. We included studies that

  5. Reporting and methodological quality of survival analysis in articles published in Chinese oncology journals.

    Science.gov (United States)

    Zhu, Xiaoyan; Zhou, Xiaobin; Zhang, Yuan; Sun, Xiao; Liu, Haihua; Zhang, Yingying

    2017-12-01

    Survival analysis methods have gained widespread use in the filed of oncology. For achievement of reliable results, the methodological process and report quality is crucial. This review provides the first examination of methodological characteristics and reporting quality of survival analysis in articles published in leading Chinese oncology journals.To examine methodological and reporting quality of survival analysis, to identify some common deficiencies, to desirable precautions in the analysis, and relate advice for authors, readers, and editors.A total of 242 survival analysis articles were included to be evaluated from 1492 articles published in 4 leading Chinese oncology journals in 2013. Articles were evaluated according to 16 established items for proper use and reporting of survival analysis.The application rates of Kaplan-Meier, life table, log-rank test, Breslow test, and Cox proportional hazards model (Cox model) were 91.74%, 3.72%, 78.51%, 0.41%, and 46.28%, respectively, no article used the parametric method for survival analysis. Multivariate Cox model was conducted in 112 articles (46.28%). Follow-up rates were mentioned in 155 articles (64.05%), of which 4 articles were under 80% and the lowest was 75.25%, 55 articles were100%. The report rates of all types of survival endpoint were lower than 10%. Eleven of 100 articles which reported a loss to follow-up had stated how to treat it in the analysis. One hundred thirty articles (53.72%) did not perform multivariate analysis. One hundred thirty-nine articles (57.44%) did not define the survival time. Violations and omissions of methodological guidelines included no mention of pertinent checks for proportional hazard assumption; no report of testing for interactions and collinearity between independent variables; no report of calculation method of sample size. Thirty-six articles (32.74%) reported the methods of independent variable selection. The above defects could make potentially inaccurate

  6. Methodology for Assessing the Quality of Agribusiness Activity Based on the Environmentally Responsible Approach

    Directory of Open Access Journals (Sweden)

    Anna Antonovna Anfinogentova

    2017-06-01

    Full Text Available The article is devoted to the research and development of quality evaluation methods of agro-industrial enterprises activity in the regional economy with the use of the ecological approach. The hypothesis of the study is that the activity of the economic entities (as well as of agribusiness must be assessed not only in the context of economic efficiency and effectiveness, but also in the context of environmental ethics and environmental aggression. As the initial data, we have used the indicators of economic statistics of Russian agrarian-oriented regions, as well as the data received from management reporting on the sample of enterprises of three regions (the Belgorod and Moscow regions, Krasnodar Territory. The article offers the economic and mathematical approach for measuring the level of the environmental responsibility of agro-industrial enterprises on the basic formula of the Mandelbrot set and statistical indicator of Hurst. Our scientific contribution is the development of a modified methodology for assessing the quality of the activity of agro-industrial enterprises using the parameter characterizing the level of environmental ethics and environmental aggression of these entities. The main result of the study is the approbation of the method, which has shown its practical applicability and relative coherence with certain indicators of regional ecological statistics. The proposed method is characterized by the integration of the different mathematical approaches and as an adaptive assessment tool that can be used to assess the quality of the activity of both agro-industrial enterprises and enterprises of other industries and fields of the economy. In the further works, the authors plan to develop methodological approaches to the assessment of the quality of agro-industrial products. At the same time, the main attention will be paid to the ecological and social component of the quality.

  7. A methodology of healthcare quality measurement: a case study

    International Nuclear Information System (INIS)

    Pecoraro, F; Luzi, D; Federico II, Naples (Italy))" data-affiliation=" (Department of Electrical Engineering and Information Technology and Interuniversity Centre of Bioengineering of the Human Neuromusculoskeletal System, University of Naples, Federico II, Naples (Italy))" >Cesarelli, M; Clemente, F

    2015-01-01

    In this paper we present a comprehensive model for quality assessment taking into account structure, process and outcome dimensions introduced in the Donabedian framework. To test our hypothesis a case study based on the Italian healthcare services is reported focusing on the analysis of the hospital bed management and on the phenomenon of both active and passive patient mobility

  8. Measurement of quality of life I. A methodological framework

    DEFF Research Database (Denmark)

    Ventegodt, Søren; Hilden, Jørgen; Merrick, Joav

    2003-01-01

    meet to provide a sound basis for investigation by questionnaire. The seven criteria or desiderata are: (1) an explicit definition of quality of life; (2) a coherent philosophy of human life from which the definition is derived; (3) a theory that operationalizes the philosophy by specifying unambiguous...

  9. Screening of Dementia in Portuguese Primary Care: Methodology, Assessment Tools, and Main Results

    Directory of Open Access Journals (Sweden)

    Laetitia Teixeira

    2017-11-01

    Full Text Available The objectives of this article are as follows: (1 to describe the assessment protocol used to outline people with probable dementia in Primary Health Care; (2 to show the methodological design and procedure to obtain a representative sample of patients with probable dementia; and (3 to report the main characteristics of the sample collected in the context of the study “Characteristics and needs of people with probable dementia.” The study protocol was based on the “Community Assessment of Risk and Treatment Strategies (CARTS Program” and is composed by a set of instruments that allow the assessment of older adults with probable dementia in several areas (health, psychological, functionality, and other. Descriptive analysis was used to characterize the final sample (n = 436. The study protocol as well as the methodological procedure to obtain the referral of research participants and data collection on the condition of people with probable dementia in Primary Health Care proved to be a valuable tool to obtain a sample of patients distributed by the full range of probable dementia in a large geographical area. Results may allocate the design of care pathways for old people with cognitive disorders to prevent, delay impairment, and/or optimize quality of life of patients.

  10. Terminology and methodology in modelling for water quality management

    DEFF Research Database (Denmark)

    Carstensen, J.; Vanrolleghem, P.; Rauch, W.

    1997-01-01

    There is a widespread need for a common terminology in modelling for water quality management. This paper points out sources of confusion in the communication between researchers due to misuse of existing terminology or use of unclear terminology. The paper attempts to clarify the context...... of the most widely used terms for characterising models and within the process of model building. It is essential to the ever growing society of researchers within water quality management, that communication is eased by establishing a common terminology. This should not be done by giving broader definitions...... of the terms, but by stressing the use of a stringent terminology. Therefore, the goal of the paper is to advocate the use of such a well defined and clear terminology. (C) 1997 IAWQ. Published by Elsevier Science Ltd....

  11. KAIZEN METHODOLOGY IN QUALITY MANAGEMENT TO REDUCE WASTES

    Directory of Open Access Journals (Sweden)

    Boca Gratiela Dana

    2011-01-01

    Full Text Available Kaizen cannot deal with all problems and one size does not fit all but a flexibleimplementation opens up the dimension of collaboration between the workforce, themanagement and the technical departments. In every company, it operates in a differentway to suit the circumstances but all consider it indispensable. It is more flexible andtolerant than may be expected; it is a tool for integration of technological strategy with thebusiness strategy of the organization. Technology is forcing organizations to become morecompetitive as at every instance innovations take place. Recent innovations in the form oftotal quality management, reengineering work process, flexible manufacturing system haveonly one thing in common - well serving the customer by improved operational efficiency.For instant Quality Management advocates emphasize the importance of achieving higherquality and flexibility at lower level of cost and waste.

  12. A methodology for texture feature-based quality assessment in nucleus segmentation of histopathology image

    Directory of Open Access Journals (Sweden)

    Si Wen

    2017-01-01

    Full Text Available Context: Image segmentation pipelines often are sensitive to algorithm input parameters. Algorithm parameters optimized for a set of images do not necessarily produce good-quality-segmentation results for other images. Even within an image, some regions may not be well segmented due to a number of factors, including multiple pieces of tissue with distinct characteristics, differences in staining of the tissue, normal versus tumor regions, and tumor heterogeneity. Evaluation of quality of segmentation results is an important step in image analysis. It is very labor intensive to do quality assessment manually with large image datasets because a whole-slide tissue image may have hundreds of thousands of nuclei. Semi-automatic mechanisms are needed to assist researchers and application developers to detect image regions with bad segmentations efficiently. Aims: Our goal is to develop and evaluate a machine-learning-based semi-automated workflow to assess quality of nucleus segmentation results in a large set of whole-slide tissue images. Methods: We propose a quality control methodology, in which machine-learning algorithms are trained with image intensity and texture features to produce a classification model. This model is applied to image patches in a whole-slide tissue image to predict the quality of nucleus segmentation in each patch. The training step of our methodology involves the selection and labeling of regions by a pathologist in a set of images to create the training dataset. The image regions are partitioned into patches. A set of intensity and texture features is computed for each patch. A classifier is trained with the features and the labels assigned by the pathologist. At the end of this process, a classification model is generated. The classification step applies the classification model to unlabeled test images. Each test image is partitioned into patches. The classification model is applied to each patch to predict the patch

  13. A new transmission methodology for quality assurance in radiotherapy based on radiochromic film measurements

    Science.gov (United States)

    do Amaral, Leonardo L.; Pavoni, Juliana F.; Sampaio, Francisco; Netto, Thomaz Ghilardi

    2015-01-01

    Despite individual quality assurance (QA) being recommended for complex techniques in radiotherapy (RT) treatment, the possibility of errors in dose delivery during therapeutic application has been verified. Therefore, it is fundamentally important to conduct in vivo QA during treatment. This work presents an in vivo transmission quality control methodology, using radiochromic film (RCF) coupled to the linear accelerator (linac) accessory holder. This QA methodology compares the dose distribution measured by the film in the linac accessory holder with the dose distribution expected by the treatment planning software. The calculated dose distribution is obtained in the coronal and central plane of a phantom with the same dimensions of the acrylic support used for positioning the film but in a source‐to‐detector distance (SDD) of 100 cm, as a result of transferring the IMRT plan in question with all the fields positioned with the gantry vertically, that is, perpendicular to the phantom. To validate this procedure, first of all a Monte Carlo simulation using PENELOPE code was done to evaluate the differences between the dose distributions measured by the film in a SDD of 56.8 cm and 100 cm. After that, several simple dose distribution tests were evaluated using the proposed methodology, and finally a study using IMRT treatments was done. In the Monte Carlo simulation, the mean percentage of points approved in the gamma function comparing the dose distribution acquired in the two SDDs were 99.92%±0.14%. In the simple dose distribution tests, the mean percentage of points approved in the gamma function were 99.85%±0.26% and the mean percentage differences in the normalization point doses were −1.41%. The transmission methodology was approved in 24 of 25 IMRT test irradiations. Based on these results, it can be concluded that the proposed methodology using RCFs can be applied for in vivo QA in RT treatments. PACS number: 87.55.Qr, 87.55.km, 87.55.N‐ PMID

  14. Integrated vehicle-based safety systems light-vehicle field operational test, methodology and results report.

    Science.gov (United States)

    2010-12-01

    "This document presents the methodology and results from the light-vehicle field operational test conducted as part of the Integrated Vehicle-Based Safety Systems program. These findings are the result of analyses performed by the University of Michi...

  15. A novel methodology for interpreting air quality measurements from urban streets using CFD modelling

    Science.gov (United States)

    Solazzo, Efisio; Vardoulakis, Sotiris; Cai, Xiaoming

    2011-09-01

    In this study, a novel computational fluid dynamics (CFD) based methodology has been developed to interpret long-term averaged measurements of pollutant concentrations collected at roadside locations. The methodology is applied to the analysis of pollutant dispersion in Stratford Road (SR), a busy street canyon in Birmingham (UK), where a one-year sampling campaign was carried out between August 2005 and July 2006. Firstly, a number of dispersion scenarios are defined by combining sets of synoptic wind velocity and direction. Assuming neutral atmospheric stability, CFD simulations are conducted for all the scenarios, by applying the standard k-ɛ turbulence model, with the aim of creating a database of normalised pollutant concentrations at specific locations within the street. Modelled concentration for all wind scenarios were compared with hourly observed NO x data. In order to compare with long-term averaged measurements, a weighted average of the CFD-calculated concentration fields was derived, with the weighting coefficients being proportional to the frequency of each scenario observed during the examined period (either monthly or annually). In summary the methodology consists of (i) identifying the main dispersion scenarios for the street based on wind speed and directions data, (ii) creating a database of CFD-calculated concentration fields for the identified dispersion scenarios, and (iii) combining the CFD results based on the frequency of occurrence of each dispersion scenario during the examined period. The methodology has been applied to calculate monthly and annually averaged benzene concentration at several locations within the street canyon so that a direct comparison with observations could be made. The results of this study indicate that, within the simplifying assumption of non-buoyant flow, CFD modelling can aid understanding of long-term air quality measurements, and help assessing the representativeness of monitoring locations for population

  16. [Methodological quality and reporting quality evaluation of randomized controlled trials published in China Journal of Chinese Materia Medica].

    Science.gov (United States)

    Yu, Dan-Dan; Xie, Yan-Ming; Liao, Xing; Zhi, Ying-Jie; Jiang, Jun-Jie; Chen, Wei

    2018-02-01

    To evaluate the methodological quality and reporting quality of randomized controlled trials(RCTs) published in China Journal of Chinese Materia Medica, we searched CNKI and China Journal of Chinese Materia webpage to collect RCTs since the establishment of the magazine. The Cochrane risk of bias assessment tool was used to evaluate the methodological quality of RCTs. The CONSORT 2010 list was adopted as reporting quality evaluating tool. Finally, 184 RCTs were included and evaluated methodologically, of which 97 RCTs were evaluated with reporting quality. For the methodological evaluating, 62 trials(33.70%) reported the random sequence generation; 9(4.89%) trials reported the allocation concealment; 25(13.59%) trials adopted the method of blinding; 30(16.30%) trials reported the number of patients withdrawing, dropping out and those lost to follow-up;2 trials (1.09%) reported trial registration and none of the trial reported the trial protocol; only 8(4.35%) trials reported the sample size estimation in details. For reporting quality appraising, 3 reporting items of 25 items were evaluated with high-quality,including: abstract, participants qualified criteria, and statistical methods; 4 reporting items with medium-quality, including purpose, intervention, random sequence method, and data collection of sites and locations; 9 items with low-quality reporting items including title, backgrounds, random sequence types, allocation concealment, blindness, recruitment of subjects, baseline data, harms, and funding;the rest of items were of extremely low quality(the compliance rate of reporting item<10%). On the whole, the methodological and reporting quality of RCTs published in the magazine are generally low. Further improvement in both methodological and reporting quality for RCTs of traditional Chinese medicine are warranted. It is recommended that the international standards and procedures for RCT design should be strictly followed to conduct high-quality trials

  17. Impact Evaluation of Quality Assurance in Higher Education: Methodology and Causal Designs

    Science.gov (United States)

    Leiber, Theodor; Stensaker, Bjørn; Harvey, Lee

    2015-01-01

    In this paper, the theoretical perspectives and general methodological elements of impact evaluation of quality assurance in higher education institutions are discussed, which should be a cornerstone of quality development in higher education and contribute to improving the knowledge about the effectiveness (or ineffectiveness) of quality…

  18. Quality Assurance and Its Impact from Higher Education Institutions' Perspectives: Methodological Approaches, Experiences and Expectations

    Science.gov (United States)

    Bejan, Stelian Andrei; Janatuinen, Tero; Jurvelin, Jouni; Klöpping, Susanne; Malinen, Heikki; Minke, Bernhard; Vacareanu, Radu

    2015-01-01

    This paper reports on methodological approaches, experiences and expectations referring to impact analysis of quality assurance from the perspective of three higher education institutions (students, teaching staff, quality managers) from Germany, Finland and Romania. The presentations of the three sample institutions focus on discussing the core…

  19. Methodological Validation of Quality of Life Questionnaire for Coal Mining Groups-Indian Scenario

    Science.gov (United States)

    Sen, Sayanti; Sen, Goutam; Tewary, B. K.

    2012-01-01

    Maslow's hierarchy-of-needs theory has been used to predict development of Quality of Life (QOL) in countries over time. In this paper an attempt has been taken to derive a methodological validation of quality of life questionnaire which have been prepared for the study area. The objective of the study is to standardize a questionnaire tool to…

  20. Report on use of a methodology for commissioning and quality assurance of a VMAT system.

    Directory of Open Access Journals (Sweden)

    Charles Mayo

    Full Text Available INTRODUCTION: Results of use of methodology for VMAT commissioning and quality assurance, utilizing both control point tests and dosimetric measurements are presented. METHODS AND MATERIALS: A generalizable, phantom measurement approach is used to characterize the accuracy of the measurement system. Correction for angular response of the measurement system and inclusion of couch structures are used to characterize the full range gantry angles desirable for clinical plans. A dose based daily QA measurement approach is defined. RESULTS: Agreement in the static vs. VMAT picket fence control point test was better than 0.5 mm. Control point tests varying gantry rotation speed, leaf speed and dose rate, demonstrated agreement with predicted values better than 1%. Angular dependence of the MatriXX array, varied over a range of 0.94-1.06, with respect to the calibration condition. Phantom measurements demonstrated central axis dose accuracy for un-modulated four field box plans was ≥2.5% vs. 1% with and without angular correction respectively with better results for VMAT (0.4% vs. IMRT (1.6% plans. Daily QA results demonstrated average agreement all three chambers within 0.4% over 9 month period with no false positives at a 3% threshold. DISCUSSION: The methodology described is simple in design and characterizes both the inherit limitations of the measurement system as well at the dose based measurements that may be directly related to patient plan QA.

  1. "Assessing the methodological quality of systematic reviews in radiation oncology: A systematic review".

    Science.gov (United States)

    Hasan, Haroon; Muhammed, Taaha; Yu, Jennifer; Taguchi, Kelsi; Samargandi, Osama A; Howard, A Fuchsia; Lo, Andrea C; Olson, Robert; Goddard, Karen

    2017-10-01

    The objective of our study was to evaluate the methodological quality of systematic reviews and meta-analyses in Radiation Oncology. A systematic literature search was conducted for all eligible systematic reviews and meta-analyses in Radiation Oncology from 1966 to 2015. Methodological characteristics were abstracted from all works that satisfied the inclusion criteria and quality was assessed using the critical appraisal tool, AMSTAR. Regression analyses were performed to determine factors associated with a higher score of quality. Following exclusion based on a priori criteria, 410 studies (157 systematic reviews and 253 meta-analyses) satisfied the inclusion criteria. Meta-analyses were found to be of fair to good quality while systematic reviews were found to be of less than fair quality. Factors associated with higher scores of quality in the multivariable analysis were including primary studies consisting of randomized control trials, performing a meta-analysis, and applying a recommended guideline related to establishing a systematic review protocol and/or reporting. Systematic reviews and meta-analyses may introduce a high risk of bias if applied to inform decision-making based on AMSTAR. We recommend that decision-makers in Radiation Oncology scrutinize the methodological quality of systematic reviews and meta-analyses prior to assessing their utility to inform evidence-based medicine and researchers adhere to methodological standards outlined in validated guidelines when embarking on a systematic review. Copyright © 2017 Elsevier Ltd. All rights reserved.

  2. Does Deregulation of Quality Standards in Telecomunications Improve Social Welfare? A Methodological Note Does Deregulation of Quality Standards in Telecomunications Improve Social Welfare? A Methodological Note

    OpenAIRE

    Felipe Morandé

    1990-01-01

    Does Deregulation of Quality Standards in Telecomunications Improve Social Welfare? A Methodological Note One of the main reasons behind the bit difference observed in the per capita number of telephones between develope and developing countries is the high capital cost -a scarce resource in LDC's- of expanding telecommunications infrastructure. A reasonable question to raise in this context is the extent to which that high capital cost of investment could be diminished if international quali...

  3. Comparison of methodological quality rating of systematic reviews on neuropathic pain using AMSTAR and R-AMSTAR.

    Science.gov (United States)

    Dosenovic, Svjetlana; Jelicic Kadic, Antonia; Vucic, Katarina; Markovina, Nikolina; Pieper, Dawid; Puljak, Livia

    2018-05-08

    Systematic reviews (SRs) in the field of neuropathic pain (NeuP) are increasingly important for decision-making. However, methodological flaws in SRs can reduce the validity of conclusions. Hence, it is important to assess the methodological quality of NeuP SRs critically. Additionally, it remains unclear which assessment tool should be used. We studied the methodological quality of SRs published in the field of NeuP and compared two assessment tools. We systematically searched 5 electronic databases to identify SRs of randomized controlled trials of interventions for NeuP available up to March 2015. Two independent reviewers assessed the methodological quality of the studies using the Assessment of Multiple Systematic Reviews (AMSTAR) and the revised AMSTAR (R-AMSTAR) tools. The scores were converted to percentiles and ranked into 4 grades to allow comparison between the two checklists. Gwet's AC1 coefficient was used for interrater reliability assessment. The 97 included SRs had a wide range of methodological quality scores (AMSTAR median (IQR): 6 (5-8) vs. R-AMSTAR median (IQR): 30 (26-35)). The overall agreement score between the 2 raters was 0.62 (95% CI 0.39-0.86) for AMSTAR and 0.62 (95% CI 0.53-0.70) for R-AMSTAR. The 31 Cochrane systematic reviews (CSRs) were consistently ranked higher than the 66 non-Cochrane systematic reviews (NCSRs). The analysis of individual domains showed the best compliance in a comprehensive literature search (item 3) on both checklists. The results for the domain that was the least compliant differed: conflict of interest (item 11) was the item most poorly reported on AMSTAR vs. publication bias assessment (item 10) on R-AMSTAR. A high positive correlation between the total AMSTAR and R-AMSTAR scores for all SRs, as well as for CSRs and NCSRs, was observed. The methodological quality of analyzed SRs in the field of NeuP was not optimal, and CSRs had a higher quality than NCSRs. Both AMSTAR and R-AMSTAR tools produced comparable

  4. Methodologic quality and relevance of references in pharmaceutical advertisements in a Canadian medical journal.

    Science.gov (United States)

    Lexchin, J; Holbrook, A

    1994-07-01

    To evaluate the methodologic quality and relevance of references in pharmaceutical advertisements in the Canadian Medical Association Journal (CMAJ). Analytic study. All 114 references cited in the first 22 distinct pharmaceutical advertisements in volume 146 of CMAJ. Mean methodologic quality score (modified from the 6-point scale used to assess articles in the American College of Physicians' Journal Club) and mean relevance score (based on a new 5-point scale) for all references in each advertisement. Twenty of the 22 companies responded, sending 78 (90%) of the 87 references requested. The mean methodologic quality score was 58% (95% confidence limits [CL] 51% and 65%) and the mean relevance score 76% (95% CL 72% and 80%). The two mean scores were statistically lower than the acceptable score of 80% (p e., other than reports of clinical trials). Half of the advertisements had a methodologic quality score of less than 65%, but only five had a relevance score of less than 65%. Although the relevance of most of the references was within minimal acceptable limits, the methodologic quality was often unacceptable. Because advertisements are an important part of pharmaceutical marketing and education, we suggest that companies develop written standards for their advertisements and monitor their advertisements for adherence to these standards. We also suggest that the Pharmaceutical Advertising Advisory Board develop more stringent guidelines for advertising and that it enforce these guidelines in a consistent, rigorous fashion.

  5. Self-propelled prospection methodology: first results obtained in the northeast basin (Uruguay)

    International Nuclear Information System (INIS)

    Goso, H; Spoturno, J; Peciozzi, F.

    2008-01-01

    This report refers about uranium prospection methodology in Uruguay and its first results obtained in the northeast basin.The preliminary radiometric researching is carried out four works phases: material preparation, radiometric, statistics analysis, anomalies revision

  6. Google chemtrails: a methodology to analyze topic representation in search engine results

    OpenAIRE

    Ballatore, Andrea

    2015-01-01

    Search engine results influence the visibility of different viewpoints in political, cultural, and scientific debates. Treating search engines as editorial products with intrinsic biases can help understand the structure of information flows in new media. This paper outlines an empirical methodology to analyze the representation of topics in search engines, reducing the spatial and temporal biases in the results. As a case study, the methodology is applied to 15 popular conspiracy theories, e...

  7. Methodology of the Integrated Analysis of Company's Financial Status and Its Performance Results

    OpenAIRE

    Mackevičius, Jonas; Valkauskas, Romualdas

    2010-01-01

    Information about company's financial status and its performance results is very important for the objective evaluation of company's position in the market and competitive possibilities in the future. Such information is provided in the financial statement. It is important to apply and investigate this information properly. The methodology of company's financial status and performance results integrated analysis is recommended in this article. This methodology consists of these three elements...

  8. Quality-driven methodology for demanding accelarator design

    NARCIS (Netherlands)

    Jozwiak, L.; Jan, Y.

    2010-01-01

    This paper focuses on mastering the architecture development of hardware accelerators for demanding applications. It presents the results of our analysis of the main problems that have to be solved when designing accelerators for modern demanding applications, and illustrates the problems with an

  9. Methodological quality and descriptive characteristics of prosthodontic-related systematic reviews.

    Science.gov (United States)

    Aziz, T; Compton, S; Nassar, U; Matthews, D; Ansari, K; Flores-Mir, C

    2013-04-01

    Ideally, healthcare systematic reviews (SRs) should be beneficial to practicing professionals in making evidence-based clinical decisions. However, the conclusions drawn from SRs are directly related to the quality of the SR and of the included studies. The aim was to investigate the methodological quality and key descriptive characteristics of SRs published in prosthodontics. Methodological quality was analysed using the Assessment of Multiple Reviews (AMSTAR) tool. Several electronic resources (MEDLINE, EMBASE, Web of Science and American Dental Association's Evidence-based Dentistry website) were searched. In total 106 SRs were located. Key descriptive characteristics and methodological quality features were gathered and assessed, and descriptive and inferential statistical testing performed. Most SRs in this sample originated from the European continent followed by North America. Two to five authors conducted most SRs; the majority was affiliated with academic institutions and had prior experience publishing SRs. The majority of SRs were published in specialty dentistry journals, with implant or implant-related topics, the primary topics of interest for most. According to AMSTAR, most quality aspects were adequately fulfilled by less than half of the reviews. Publication bias and grey literature searches were the most poorly adhered components. Overall, the methodological quality of the prosthodontic-related systematic was deemed limited. Future recommendations would include authors to have prior training in conducting SRs and for journals to include a universal checklist that should be adhered to address all key characteristics of an unbiased SR process. © 2013 Blackwell Publishing Ltd.

  10. The methodological quality of systematic reviews of animal studies in dentistry.

    Science.gov (United States)

    Faggion, C M; Listl, S; Giannakopoulos, N N

    2012-05-01

    Systematic reviews and meta-analyses of animal studies are important for improving estimates of the effects of treatment and for guiding future clinical studies on humans. The purpose of this systematic review was to assess the methodological quality of systematic reviews and meta-analyses of animal studies in dentistry through using a validated checklist. A literature search was conducted independently and in duplicate in the PubMed and LILACS databases. References in selected systematic reviews were assessed to identify other studies not captured by the electronic searches. The methodological quality of studies was assessed independently and in duplicate by using the AMSTAR checklist; the quality was scored as low, moderate, or high. The reviewers were calibrated before the assessment and agreement between them was assessed using Cohen's Kappa statistic. Of 444 studies retrieved, 54 systematic reviews were selected after full-text assessment. Agreement between the reviewers was regarded as excellent. Only two studies were scored as high quality; 17 and 35 studies were scored as medium and low quality, respectively. There is room for improvement of the methodological quality of systematic reviews of animal studies in dentistry. Checklists, such as AMSTAR, can guide researchers in planning and executing systematic reviews and meta-analyses. For determining the need for additional investigations in animals and in order to provide good data for potential application in human, such reviews should be based on animal experiments performed according to sound methodological principles. Copyright © 2011 Elsevier Ltd. All rights reserved.

  11. A conceptual design methodology for enhanced conformance quality

    Energy Technology Data Exchange (ETDEWEB)

    Hinckley, C.M. [Sandia National Labs., Livermore, CA (United States); Barkan, P. [Stanford Univ., Stanford, CA (United States). Dept. of Mechanical Engineering

    1995-12-31

    Traditional manufacturing practice has depended upon Statistical Process Control (SPC) to eliminate defects. However, our research demonstrates that these sampling based methods significantly underestimate the tails of a distribution. As a consequence of the limitations of SPC, mistakes require different methods of control to achieve defect rates in the tens of parts per million range. Furthermore, product complexity contributes to defects resulting from both mistakes and excess variation. Correlations between defects and complexity lead to a new opportunity for selecting superior product concepts.

  12. Identifying approaches for assessing methodological and reporting quality of systematic reviews

    DEFF Research Database (Denmark)

    Pussegoda, Kusala; Turner, Lucy; Garritty, Chantelle

    2017-01-01

    there are potential gaps in research best-practice guidance materials. The aims of this study are to identify reports assessing the methodological quality (MQ) and/or reporting quality (RQ) of a cohort of SRs and to assess their number, general characteristics, and approaches to 'quality' assessment over time......BACKGROUND: The methodological quality and completeness of reporting of the systematic reviews (SRs) is fundamental to optimal implementation of evidence-based health care and the reduction of research waste. Methods exist to appraise SRs yet little is known about how they are used in SRs or where...... or reporting guidelines used as proxy to assess RQ were used in 80% (61/76) of identified reports. These included two reporting guidelines (PRISMA and QUOROM) and five quality assessment tools (AMSTAR, R-AMSTAR, OQAQ, Mulrow, Sacks) and GRADE criteria. The remaining 24% (18/76) of reports developed their own...

  13. Use of TANDEM methodology for quality control in radiation protection

    International Nuclear Information System (INIS)

    Mello, O.A.; Oliveira, I.R.; Leyton, F.; Nogueira, M.S.; Borges, F.L.S.; Joana, G.S.

    2014-01-01

    Recent studies have indicated the increase of the incidence of lens opacities for low radiation doses. Considering epidemiological data, the International Commission on Radiological Protection (ICRP) issued a statement that changed the absorbed dose threshold for the eye lens. The statement also recommends a reduction in the dose limits to the eye lens for occupationally exposed persons; now it is considered to be 20 mSv in a year averaged over five years. For this research two types of thermoluminescent dosimeters TL were used in the construction of the curve tandem. (LiF-100H e LiF-200). For system calibration three monitors were irradiated for each radiation beam. The monitors were irradiated with 4 mGy kerma at 1.5 m from the focal point. The Tandem curve was obtained by the ratio between the values of the energy dependence curves of each dosimeter. Data obtained for the corresponding x-ray beams to radiation reference N60 to N120 are more accurate for determining the energy - steepest part of the curve. The results are shown similar to similar studies and confirm the possibility of using the method for determining the unknown energy radiation fields. (author)

  14. Methodological quality of systematic reviews in subfertility: a comparison of two different approaches.

    Directory of Open Access Journals (Sweden)

    Ivor Popovich

    Full Text Available BACKGROUND: Systematic reviews are used widely to guide health care decisions. Several tools have been created to assess systematic review quality. The measurement tool for assessing the methodological quality of systematic reviews known as the AMSTAR tool applies a yes/no score to eleven relevant domains of review methodology. This tool has been reworked so that each domain is scored based on a four point scale, producing R-AMSTAR. METHODS AND FINDINGS: We aimed to compare the AMSTAR and R-AMSTAR tools in assessing systematic reviews in the field of assisted reproduction for subfertility. All published systematic reviews on assisted reproductive technology, with the latest search for studies taking place from 2007-2011, were considered. Reviews that contained no included studies or considered diagnostic outcomes were excluded. Thirty each of Cochrane and non-Cochrane reviews were randomly selected from a search of relevant databases. Both tools were then applied to all sixty reviews. The results were converted to percentage scores and all reviews graded and ranked based on this. AMSTAR produced a much wider variation in percentage scores and achieved higher inter-rater reliability than R-AMSTAR according to kappa statistics. The average rating for Cochrane reviews was consistent between the two tools (88.3% for R-AMSTAR versus 83.6% for AMSTAR but inconsistent for non-Cochrane reviews (63.9% R-AMSTAR vs. 38.5% AMSTAR. In comparing the rankings generated between the two tools Cochrane reviews changed an average of 4.2 places, compared to 2.9 for non-Cochrane. CONCLUSION: R-AMSTAR provided greater guidance in the assessment of domains and produced quantitative results. However, there were many problems with the construction of its criteria and AMSTAR was much easier to apply consistently. We recommend that AMSTAR incorporates the findings of this study and produces additional guidance for its application in order to improve its reliability and

  15. Social cognition interventions for people with schizophrenia: a systematic review focussing on methodological quality and intervention modality.

    Science.gov (United States)

    Grant, Nina; Lawrence, Megan; Preti, Antonio; Wykes, Til; Cella, Matteo

    2017-08-01

    People with a diagnosis of schizophrenia have significant social and functional difficulties. Social cognition was found to influences these outcomes and in recent years interventions targeting this domain were developed. This paper reviews the existing literature on social cognition interventions for people with a diagnosis of schizophrenia focussing on: i) comparing focussed (i.e. targeting only one social cognitive domain) and global interventions and ii) studies methodological quality. Systematic search was conducted on PubMed and PsycInfo. Studies were included if they were randomised control trials, participants had a diagnosis of schizophrenia or schizoaffective disorder, and the intervention targeted at least one out of four social cognition domains (i.e. theory of mind, affect recognition, social perception and attribution bias). All papers were assessed for methodological quality. Information on the intervention, control condition, study methodology and the main findings from each study were extracted and critically summarised. Data from 32 studies fulfilled the inclusion criteria, considering a total of 1440 participants. Taking part in social cognition interventions produced significant improvements in theory of mind and affect recognition compared to both passive and active control conditions. Results were less clear for social perception and attributional bias. Focussed and global interventions had similar results on outcomes. Overall study methodological quality was modest. There was very limited evidence showing that social cognitive intervention result in functional outcome improvement. The evidence considered suggests that social cognition interventions may be a valuable approach for people with a diagnosis of schizophrenia. However, evidence quality is limited by measure heterogeneity, modest study methodology and short follow-up periods. The findings point to a number of recommendations for future research, including measurement standardisation

  16. Residency Training: Quality improvement projects in neurology residency and fellowship: applying DMAIC methodology.

    Science.gov (United States)

    Kassardjian, Charles D; Williamson, Michelle L; van Buskirk, Dorothy J; Ernste, Floranne C; Hunderfund, Andrea N Leep

    2015-07-14

    Teaching quality improvement (QI) is a priority for residency and fellowship training programs. However, many medical trainees have had little exposure to QI methods. The purpose of this study is to review a rigorous and simple QI methodology (define, measure, analyze, improve, and control [DMAIC]) and demonstrate its use in a fellow-driven QI project aimed at reducing the number of delayed and canceled muscle biopsies at our institution. DMAIC was utilized. The project aim was to reduce the number of delayed muscle biopsies to 10% or less within 24 months. Baseline data were collected for 12 months. These data were analyzed to identify root causes for muscle biopsy delays and cancellations. Interventions were developed to address the most common root causes. Performance was then remeasured for 9 months. Baseline data were collected on 97 of 120 muscle biopsies during 2013. Twenty biopsies (20.6%) were delayed. The most common causes were scheduling too many tests on the same day and lack of fasting. Interventions aimed at patient education and biopsy scheduling were implemented. The effect was to reduce the number of delayed biopsies to 6.6% (6/91) over the next 9 months. Familiarity with QI methodologies such as DMAIC is helpful to ensure valid results and conclusions. Utilizing DMAIC, we were able to implement simple changes and significantly reduce the number of delayed muscle biopsies at our institution. © 2015 American Academy of Neurology.

  17. Inkjet printed large-area flexible circuits: a simple methodology for optimizing the printing quality

    Science.gov (United States)

    Cheng, Tao; Wu, Youwei; Shen, Xiaoqin; Lai, Wenyong; Huang, Wei

    2018-01-01

    In this work, a simple methodology was developed to enhance the patterning resolution of inkjet printing, involving process optimization as well as substrate modification and treatment. The line width of the inkjet-printed silver lines was successfully reduced to 1/3 of the original value using this methodology. Large-area flexible circuits with delicate patterns and good morphology were thus fabricated. The resultant flexible circuits showed excellent electrical conductivity as low as 4.5 Ω/□ and strong tolerance to mechanical bending. The simple methodology is also applicable to substrates with various wettability, which suggests a general strategy to enhance the printing quality of inkjet printing for manufacturing high-performance large-area flexible electronics. Project supported by the National Key Basic Research Program of China (Nos. 2014CB648300, 2017YFB0404501), the National Natural Science Foundation of China (Nos. 21422402, 21674050), the Natural Science Foundation of Jiangsu Province (Nos. BK20140060, BK20130037, BK20140865, BM2012010), the Program for Jiangsu Specially-Appointed Professors (No. RK030STP15001), the Program for New Century Excellent Talents in University (No. NCET-13-0872), the NUPT "1311 Project" and Scientific Foundation (Nos. NY213119, NY213169), the Synergetic Innovation Center for Organic Electronics and Information Displays, the Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD), the Leading Talent of Technological Innovation of National Ten-Thousands Talents Program of China, the Excellent Scientific and Technological Innovative Teams of Jiangsu Higher Education Institutions (No. TJ217038), the Program for Graduate Students Research and Innovation of Jiangsu Province (No. KYZZ16-0253), and the 333 Project of Jiangsu Province (Nos. BRA2017402, BRA2015374).

  18. #eVALUate: Monetizing Service Acquisition Trade-offs Using the QUALITY-INFUSED Price Methodology

    Science.gov (United States)

    2016-04-01

    they determine their source selection methodology along the best-value spectrum, ranging from lowest price technically acceptable (LPTA) to full...sidering factors determined to be germane to service value to the agency (Finkenstadt, 2015). Once an offeror’s prices are determined to be fair and... determine whether the quality rating system would affect the quality trade-off. In this case, the highest priced yet highest rated offeror was selected

  19. Guidance on assessing the methodological and reporting quality of toxicologically relevant studies: A scoping review.

    Science.gov (United States)

    Samuel, Gbeminiyi O; Hoffmann, Sebastian; Wright, Robert A; Lalu, Manoj Mathew; Patlewicz, Grace; Becker, Richard A; DeGeorge, George L; Fergusson, Dean; Hartung, Thomas; Lewis, R Jeffrey; Stephens, Martin L

    2016-01-01

    Assessments of methodological and reporting quality are critical to adequately judging the credibility of a study's conclusions and to gauging its potential reproducibility. To aid those seeking to assess the methodological or reporting quality of studies relevant to toxicology, we conducted a scoping review of the available guidance with respect to four types of studies: in vivo and in vitro, (quantitative) structure-activity relationships ([Q]SARs), physico-chemical, and human observational studies. Our aims were to identify the available guidance in this diverse literature, briefly summarize each document, and distill the common elements of these documents for each study type. In general, we found considerable guidance for in vivo and human studies, but only one paper addressed in vitro studies exclusively. The guidance for (Q)SAR studies and physico-chemical studies was scant but authoritative. There was substantial overlap across guidance documents in the proposed criteria for both methodological and reporting quality. Some guidance documents address toxicology research directly, whereas others address preclinical research generally or clinical research and therefore may not be fully applicable to the toxicology context without some translation. Another challenge is the degree to which assessments of methodological quality in toxicology should focus on risk of bias - as in clinical medicine and healthcare - or be broadened to include other quality measures, such as confirming the identity of test substances prior to exposure. Our review is intended primarily for those in toxicology and risk assessment seeking an entry point into the extensive and diverse literature on methodological and reporting quality applicable to their work. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

  20. Translating Oral Health-Related Quality of Life Measures: Are There Alternative Methodologies?

    Science.gov (United States)

    Brondani, Mario; He, Sarah

    2013-01-01

    Translating existing sociodental indicators to another language involves a rigorous methodology, which can be costly. Free-of-charge online translator tools are available, but have not been evaluated in the context of research involving quality of life measures. To explore the value of using online translator tools to develop oral health-related…

  1. The methodological quality of economic evaluation studies in obstetrics and gynecology: a systematic review

    NARCIS (Netherlands)

    Vijgen, Sylvia M. C.; Opmeer, Brent C.; Mol, Ben Willem J.

    2013-01-01

    We evaluated the methodological quality of economic evaluation studies in the field of obstetrics and gynecology published in the last decade. A MEDLINE search was performed to find economic evaluation studies in obstetrics and gynecology from the years 1997 through 2009. We included full economic

  2. The economics of climate change mitigation in developing countries - methodological and empirical results

    Energy Technology Data Exchange (ETDEWEB)

    Halsnaes, K.

    1997-12-01

    This thesis presents a methodological and empirical discussion of the costs associated with implementing greenhouse gas reduction strategies in developing countries. It presents a methodological framework for national costing studies and evaluates a number of associated valuation methods. The methodological framework has been applied in several developing countries as part of a UNEP project in which the author has participated, and reference is made to the results of these country studies. Some of the theoretical issues associated with the determination of the costs of emission reductions are discussed with reference to a number of World Bank and UN guidelines for project analysis in developing countries. The use of several accounting prices is recommended for mitigation projects, with a distinction being made between internationally and domestically traded goods. The consequences of using different accounting prices are discussed with respect to the methodology applied in the UNEP country studies. In conclusion the thesis reviews the results of some of the most important international studies of greenhouse gas emissions in developing countries. The review, which encompasses a total of 27 country studies, was undertaken by the author for the Intergovernmental Panel of Climate Change, the IPCC. Its conclusion is that the UNEP methodological framework and associated country study results are consistent with the recommendations and conclusions of the IPCC. (EG) 23 refs.

  3. The economics of climate change mitigation in developing countries -methodological and empirical results

    International Nuclear Information System (INIS)

    Halsnaes, K.

    1997-12-01

    This thesis presents a methodological and empirical discussion of the costs associated with implementing greenhouse gas reduction strategies in developing countries. It presents a methodological framework for national costing studies and evaluates a number of associated valuation methods. The methodological framework has been applied in several developing countries as part of a UNEP project in which the author has participated, and reference is made to the results of these country studies. Some of the theoretical issues associated with the determination of the costs of emission reductions are discussed with reference to a number of World Bank and UN guidelines for project analysis in developing countries. The use of several accounting prices is recommended for mitigation projects, with a distinction being made between internationally and domestically traded goods. The consequences of using different accounting prices are discussed with respect to the methodology applied in the UNEP country studies. In conclusion the thesis reviews the results of some of the most important international studies of greenhouse gas emissions in developing countries. The review, which encompasses a total of 27 country studies, was undertaken by the author for the Intergovernmental Panel of Climate Change, the IPCC. Its conclusion is that the UNEP methodological framework and associated country study results are consistent with the recommendations and conclusions of the IPCC. (EG) 23 refs

  4. Clinical audit, a valuable tool to improve quality of care: General methodology and applications in nephrology

    Science.gov (United States)

    Esposito, Pasquale; Dal Canton, Antonio

    2014-01-01

    Evaluation and improvement of quality of care provided to the patients are of crucial importance in the daily clinical practice and in the health policy planning and financing. Different tools have been developed, including incident analysis, health technology assessment and clinical audit. The clinical audit consist of measuring a clinical outcome or a process, against well-defined standards set on the principles of evidence-based medicine in order to identify the changes needed to improve the quality of care. In particular, patients suffering from chronic renal diseases, present many problems that have been set as topics for clinical audit projects, such as hypertension, anaemia and mineral metabolism management. Although the results of these studies have been encouraging, demonstrating the effectiveness of audit, overall the present evidence is not clearly in favour of clinical audit. These findings call attention to the need to further studies to validate this methodology in different operating scenarios. This review examines the principle of clinical audit, focusing on experiences performed in nephrology settings. PMID:25374819

  5. Methodological and Statistical Quality in Research Evaluating Nutritional Attitudes in Sports.

    Science.gov (United States)

    Kouvelioti, Rozalia; Vagenas, George

    2015-12-01

    The assessment of dietary attitudes and behaviors provides information of interest to sports nutritionists. Although there has been little analysis of the quality of research undertaken in this field, there is evidence of a number of flaws and methodological concerns in some of the studies in the available literature. This review undertook a systematic assessment of the attributes of research assessing the nutritional knowledge and attitudes of athletes and coaches. Sixty questionnaire-based studies were identified by a search of official databases using specific key terms with subsequent analysis by certain inclusion-exclusion criteria. These studies were then analyzed using 33 research quality criteria related to the methods, questionnaires, and statistics used. We found that many studies did not provide information on critical issues such as research hypotheses (92%), the gaining of ethics approval (50%) or informed consent (35%), or acknowledgment of limitations in the implementation of studies or interpretation of data (72%). Many of the samples were nonprobabilistic (85%) and rather small (42%). Many questionnaires were of unknown origin (30%), validity (72%), and reliability (70%) and resulted in low (≤ 60%) response rates (38%). Pilot testing was not undertaken in 67% of the studies. Few studies dealt with sample size (2%), power (3%), assumptions (7%), confidence intervals (3%), or effect sizes (3%). Improving some of these problems and deficits may enhance future research in this field.

  6. Development of a calibration methodology for instruments used to interventional radiology quality control

    International Nuclear Information System (INIS)

    Miranda, Jurema Aparecida de

    2009-01-01

    Interventional radiology is the technique where X radiation images are used as a tool in the conduction of diagnostic or/and therapeutic procedures. The exposition times are long for both procedures, diagnostic and therapeutic, may cause serious injuries in the patient, and also contribute to the dose of the clinical staff. In Brazil there are not yet well established rules to determine the doses and to make the dosimetry in fluoroscopic beams. There is great interest in this study, in relation to the beam quality, the half-value-layer, and others parameters. In this work a Medicor Neo Diagnomax clinical X ray generator, fluoroscopy mode, was used to develop a calibration methodology for instruments used in interventional radiology quality control. One plane parallel ionization chamber PTW was used as monitor. The ionization chambers recommended for fluoroscopy measurements had been evaluated and calibrated in relation to the IPEN Calibration Laboratory reference ionization chamber. The RQR3, RQR5 and RQR7 radiation qualities and the specific ones for fluoroscopy, RQC3, RQC5 and RQC7, were established following the norm IEC 61267. All beams characteristics were determined. Ionization chambers positioning system and the acrylic phantoms to the entrance and exit doses determination were developed and constructed. The results obtained show air kerma rates of 4.5x10 -3 , 1.2x10 -2 and 1.9x10 -2 Gy/min for RQC3, RQC5 and RQC7 respectively. Tests with and without the collimation just after the monitor chamber, were carried out and the results showed a difference of +5.5%, +0.6% e + 0.8%, confirming the importance of the collimation use in these interventionist procedures. (author)

  7. A Methodology for Virtual Enterprise Management – Results from IMS 95001/Esprit 26509 Globeman21 project

    DEFF Research Database (Denmark)

    Tølle, Martin; Vesterager, Johan; Pedersen, Jens Dahl

    2000-01-01

    This paper presents results of the recently concluded IMS Globeman21 (Global Manufacturing in the 21st Century, IMS 95001/ESPRIT 26509) project. The results is the Virtual Enterprise Concept, a Virtual Enterprise Framework based upon GERAM (ISO/DIS 15704) and a Methodology for Virtual Enterprise...... management and engineering which is related to the Virtual Enterprise Framework (VEF). Applying the VEF as a basis structure for the Methodology provides a systematic approach for preparation and engineering of virtual enterprises. The Virtual Enterprise Framework opens up the prospect of combining...... experiences in the area of virtual enterprise into an integrated whole enabling researchers or practitioners to focus on subsets of the challenge related to the realisation of the virtual enterprise potentials. In this paper the identification, concept and requirements phases of the methodology are briefly...

  8. Application of Taguchi methodology to improve the functional quality of a mechanical device

    International Nuclear Information System (INIS)

    Regeai, Awatef Omar

    2005-01-01

    Manufacturing and quality control are recognized branches of engineering management. special attention has been made to improve thr tools and methods for the purpose of improving the products quality and finding solutions for any Obstacles and/or problems during the production process. Taguchi methodology is one of the most powerful techniques for improving product and manufacturing process quality at low cost. It is a strategical and practical method that aims to assist managers and industrial engineers to tackle manufacturing quality problems in a systematic and structured manner. The potential benefit of Taguchi methodology lies in its ease of use, its emphasis on reducing variability to give more economical products and hence the accessibility to the engineering fraternity for solving real life quality problems. This study applies Taguchi methodology to improve the functional quality of a local made chain gear by a purposed heat treatment process. The hardness of steel is generally a function not of its composition only, but rather of its heat treatment. The study investigates the effects of various heat treatment parameters, including ramp rate of heating, normalizing holding time, normalizing temperature, annealing holding time, annealing temperature, hardening holding time, hardening temperature, quenching media, tempering temperature and tempering holding time upon the hardness, which is a measure of resistance to plastic deformation. Both the analysis of means (ANOM) and Signal to Noise ratio (S/N) have been carried out for determining the optimal condition of the process. A significant improvement of the functional quality characteristic (hardness) by more than 32% was obtained. The Scanning Electron Microscopy technique was used in this study to obtain visual evidence of the quality and continuous improvement of the heat treated samples. (author)

  9. Quality of reporting and of methodology of studies on interventions for trophic ulcers in leprosy: A systematic review

    Directory of Open Access Journals (Sweden)

    Forsetlund L

    2008-01-01

    Full Text Available Background: In the process of conducting a systematic review on interventions for skin lesions due to neuritis in leprosy, we assessed several primary papers with respect to the quality of reporting and methods used in the studies. Awareness of what constitutes weak points in previously conducted studies may be used to improve the planning, conducting and reporting of future clinical trials. Aims: To assess the quality of reporting and of methodology in studies of interventions for skin lesions due to neuritis in leprosy. Methods: Items of importance for preventing selection bias, detection bias, attrition bias and performance bias were among items assessed. The items for assessing methodological quality were used as a basis for making the checklist to assess the quality of reporting. Results: Out of the 854 references that we inspected eight studies were included on the basis of the inclusion criteria. The interventions tested were dressings, topical agents and footwear and in all studies healing of ulcers was the main outcome measure. Reporting of both, methods and results suffered from underreporting and disorganization. The most under-reported items were concealment of allocation, blinding of patients and outcome assessors, intention to treat and validation of outcomes. Conclusion: There is an apparent need to improve the methodological quality as well as the quality of reporting of trials in leprosy ulcer treatment. The most important threat in existing studies is the threat of selection bias. For the reporting of future studies, journals could promote and encourage the use of the CONSORT statement checklist by expecting and requiring that authors adhere to it in their reporting.

  10. [Efficiency versus quality in the NHS, in Portugal: methodologies for evaluation].

    Science.gov (United States)

    Giraldes, Maria do Rosário

    2008-01-01

    To proceed to the evaluation of the efficiency and quality in the NHS, based in methodologies of evaluation of management, indicators of benchmarking and indicators of process and outcome. The 1980 and 1990 decades have seen the proliferation of all forms of process indicators as a way to control health services. It is not a coincidence that the increase in managed care has been accompanied by an explosion of process indicators, as it has happened in the health system of the USA. More recently the attention has turned away from measures of performance, which measure the process (what has been done) to those which measure outcomes (what was the result). Quality indicators have been developed in Europe, first to be used in hospitals, but also to be used in primary health care. Conceptually the justification for the introduction of process indicators comes from the principle that their use will reinforce a modification in the quality of the proceedings, which will give origin to better outcomes as well at population level, as resource saving. Outcome indicators compared with process indicators in health care shows that process indicators have the advantage of being more sensitive than outcome indicators to differences in the quality. Optimizing health care quality has the objective of establishing a quantitative relationship between the quality of the health services and cost-effectiveness. To identify quality indicators and benchmarking and to implement plans to measure the quality of health care. In a study made in a group of senior GP, in the UK, with the objective of determining which process indicators better reflect the quality of the services in primary health care services a Delphi method was used. Only seven indicators were chosen by 75% of the respondents: the percentage of eligible patients receiving cervical screening; the percentage of generic prescribing; the percentage of eligible patients receiving childhood immunization; the percentage of eligible

  11. Systematic Review of the Application of Lean and Six Sigma Quality Improvement Methodologies in Radiology.

    Science.gov (United States)

    Amaratunga, Thelina; Dobranowski, Julian

    2016-09-01

    Preventable yet clinically significant rates of medical error remain systemic, while health care spending is at a historic high. Industry-based quality improvement (QI) methodologies show potential for utility in health care and radiology because they use an empirical approach to reduce variability and improve workflow. The aim of this review was to systematically assess the literature with regard to the use and efficacy of Lean and Six Sigma (the most popular of the industrial QI methodologies) within radiology. MEDLINE, the Allied & Complementary Medicine Database, Embase Classic + Embase, Health and Psychosocial Instruments, and the Ovid HealthStar database, alongside the Cochrane Library databases, were searched on June 2015. Empirical studies in peer-reviewed journals were included if they assessed the use of Lean, Six Sigma, or Lean Six Sigma with regard to their ability to improve a variety of quality metrics in a radiology-centered clinical setting. Of the 278 articles returned, 23 studies were suitable for inclusion. Of these, 10 assessed Six Sigma, 7 assessed Lean, and 6 assessed Lean Six Sigma. The diverse range of measured outcomes can be organized into 7 common aims: cost savings, reducing appointment wait time, reducing in-department wait time, increasing patient volume, reducing cycle time, reducing defects, and increasing staff and patient safety and satisfaction. All of the included studies demonstrated improvements across a variety of outcomes. However, there were high rates of systematic bias and imprecision as per the Grading of Recommendations Assessment, Development and Evaluation guidelines. Lean and Six Sigma QI methodologies have the potential to reduce error and costs and improve quality within radiology. However, there is a pressing need to conduct high-quality studies in order to realize the true potential of these QI methodologies in health care and radiology. Recommendations on how to improve the quality of the literature are proposed

  12. Total Quality Management Elements and Results in Higher Education Institutions: The Greek Case

    Science.gov (United States)

    Psomas, Evangelos; Antony, Jiju

    2017-01-01

    Purpose: The purpose of this paper is to determine the main total quality management (TQM) elements adopted and the respective results achieved by higher education institutions (HEIs) in Greece. Design/methodology/approach: A research study was designed and carried out in private sector Greek HEIs. Fifteen HEIs were approached through interviews…

  13. THE ARTHRITIS AND MUSCULOSKELETAL QUALITY IMPROVEMENT PROGRAM (AMQUIP: A BREAKTHROUGH SERIES METHODOLOGY PROJECT

    Directory of Open Access Journals (Sweden)

    MASTURA I

    2008-01-01

    Full Text Available The Australian government had funded the National Primary Care Collaborative (NPCC program with funding of $14.6 million over three years. One of the pilots project was the Arthritis and Musculoskeletal Quality Improvement Program (AMQuIP.The study aims to optimize general practitioners (GPs management of patients with osteoarthritis (OA of the hip and knee by identifying gaps between their current practice and best practice. The Breakthrough Series Collaborative methodology with several Plan-Do-Study-Act (PDSA cycles was employed. Participants comprises of 12 GPs/practices from two Victorian Divisions of general Practice (one rural, one metropolitan with 10 patients per GP/practice. GPs/practices attended an orientation and three learning workshops and a videoconference. GPs/practices completed PDSA cycles between workshop and reported results at workshops. GPs/practices reported use of guidelines, change in patient management and change in practice management/systems. All recruited patients completed the SF-12v2 Health Survey and WOMAC OA Index Questionnaire twice. Follow up activities including focus groups and face-to-face interviews were held six months after the final workshop. All GPs/practices used the guidelines/key messages, introduced “new” management strategies to patients, and made positive changes to their practice management/systems. Patient reported positive changes and outcomes. By using a structured methodology and evidence-based guidelines/key messages; GPs can introduce new patient management strategies, and by identifying gaps in practice management systems, positive changes can be achieved.

  14. [Types of medical registries - definitions, methodological aspects and quality of the scientific work with registries].

    Science.gov (United States)

    Mathis-Edenhofer, Stefan; Piso, Brigitte

    2011-12-01

    This work presents a comprehensive list of registry definitions including broader and narrower definitions. Compared to each other different methodological issues can be identified. Some of these issues are common for all registry types; some can be assigned more easily to a specific registry type. Instruments for evaluating the quality of registers reflect many of the mentioned aspects. Generally, and especially at registers with a descriptive or exploratory research dimension it is important to consider their intended purpose and in about it was achieved. This includes, for instance, whether the purpose and the methodology are coordinated. From the start of registration an initiator should be - based on the purpose - aware of the methodological dimension of the registry. This helps to apply the correct type of the registry, the appropriate guidance and, ultimately, the arguments for the effort (cost-benefit ratio).

  15. Methodologic quality of meta-analyses and systematic reviews on the Mediterranean diet and cardiovascular disease outcomes: a review.

    Science.gov (United States)

    Huedo-Medina, Tania B; Garcia, Marissa; Bihuniak, Jessica D; Kenny, Anne; Kerstetter, Jane

    2016-03-01

    Several systematic reviews/meta-analyses published within the past 10 y have examined the associations of Mediterranean-style diets (MedSDs) on cardiovascular disease (CVD) risk. However, these reviews have not been evaluated for satisfying contemporary methodologic quality standards. This study evaluated the quality of recent systematic reviews/meta-analyses on MedSD and CVD risk outcomes by using an established methodologic quality scale. The relation between review quality and impact per publication value of the journal in which the article had been published was also evaluated. To assess compliance with current standards, we applied a modified version of the Assessment of Multiple Systematic Reviews (AMSTARMedSD) quality scale to systematic reviews/meta-analyses retrieved from electronic databases that had met our selection criteria: 1) used systematic or meta-analytic procedures to review the literature, 2) examined MedSD trials, and 3) had MedSD interventions independently or combined with other interventions. Reviews completely satisfied from 8% to 75% of the AMSTARMedSD items (mean ± SD: 31.2% ± 19.4%), with those published in higher-impact journals having greater quality scores. At a minimum, 60% of the 24 reviews did not disclose full search details or apply appropriate statistical methods to combine study findings. Only 5 of the reviews included participant or study characteristics in their analyses, and none evaluated MedSD diet characteristics. These data suggest that current meta-analyses/systematic reviews evaluating the effect of MedSD on CVD risk do not fully comply with contemporary methodologic quality standards. As a result, there are more research questions to answer to enhance our understanding of how MedSD affects CVD risk or how these effects may be modified by the participant or MedSD characteristics. To clarify the associations between MedSD and CVD risk, future meta-analyses and systematic reviews should not only follow methodologic

  16. A comparison of results of empirical studies of supplementary search techniques and recommendations in review methodology handbooks: a methodological review.

    Science.gov (United States)

    Cooper, Chris; Booth, Andrew; Britten, Nicky; Garside, Ruth

    2017-11-28

    The purpose and contribution of supplementary search methods in systematic reviews is increasingly acknowledged. Numerous studies have demonstrated their potential in identifying studies or study data that would have been missed by bibliographic database searching alone. What is less certain is how supplementary search methods actually work, how they are applied, and the consequent advantages, disadvantages and resource implications of each search method. The aim of this study is to compare current practice in using supplementary search methods with methodological guidance. Four methodological handbooks in informing systematic review practice in the UK were read and audited to establish current methodological guidance. Studies evaluating the use of supplementary search methods were identified by searching five bibliographic databases. Studies were included if they (1) reported practical application of a supplementary search method (descriptive) or (2) examined the utility of a supplementary search method (analytical) or (3) identified/explored factors that impact on the utility of a supplementary method, when applied in practice. Thirty-five studies were included in this review in addition to the four methodological handbooks. Studies were published between 1989 and 2016, and dates of publication of the handbooks ranged from 1994 to 2014. Five supplementary search methods were reviewed: contacting study authors, citation chasing, handsearching, searching trial registers and web searching. There is reasonable consistency between recommended best practice (handbooks) and current practice (methodological studies) as it relates to the application of supplementary search methods. The methodological studies provide useful information on the effectiveness of the supplementary search methods, often seeking to evaluate aspects of the method to improve effectiveness or efficiency. In this way, the studies advance the understanding of the supplementary search methods. Further

  17. The implementation methodology of Total Quality Management in health services, as a best practice operation.

    Directory of Open Access Journals (Sweden)

    Theodora Malamou

    2016-09-01

    Full Text Available Total Quality Management – TQM (Total Quality Management-TQM, health services, is a modern management philosophy to improve the quality and efficiency of the organization as a whole, with the involvement of all employees, at all levels. According to the research data, the concept of quality is distinguished in technical, interpersonal quality and hotel infrastructure and focuses on patient satisfaction. The Critical success factors of TQM, organizations for business excellence in continuous competitive changing environment, is the management commitment, customer focus, constant communication with employees, encouragement and reward, education and scientific training, continuous improvement quality of service, interdependent relationships with suppliers, active employee participation, creation of representative indicators, targets and benchmarking, continuous outcome assessment and continuous review, review of program procedures. The purpose of this article is through the review of Greek and international literature, to introduce the methodology of a project TQM, to health services, as everyday best practice, with emphasis on quality of service. According to the literature review, TQM contributes to improving the quality of health services, the cultivation of team spirit, cooperation between health professionals and leadership, with a view to satisfy all. TQM is purely anthropocentric theory of organization and administration. We need comprehensive effort approach to improving the quality of leadership and the introduction of the culture of workers.

  18. Methodological quality of quantitative lesbian, gay, bisexual, and transgender nursing research from 2000 to 2010.

    Science.gov (United States)

    Johnson, Michael; Smyer, Tish; Yucha, Carolyn

    2012-01-01

    The purpose of this study was to evaluate the methodological quality of quantitative lesbian, gay, bisexual, and transgender nursing research from 2000 to 2010. Using a key word search in Cumulative Index to Nursing and Allied Health Literature, 188 studies were identified and 40 met the criteria, which included descriptive, experimental, quasi-experimental, or observational (case control, cohort, and cross-sectional) design. The methodological quality of these studies was similar to that reported for medical and nursing educational research. The foci of these lesbian, gay, bisexual, and transgender studies were biased toward human immunodeficiency virus, acquired immunodeficiency syndrome, and sexually transmitted diseases, and 58.5% of the funded research was related to human immunodeficiency virus or acquired immunodeficiency syndrome. To provide evidence-based health care to these populations, an understanding of the current state of research is crucial.

  19. The development of methodological tools to assess the health sector with the resulting standardized index

    Directory of Open Access Journals (Sweden)

    Hansuvarova Evgenia Adolfovna

    2016-10-01

    The proposed assessment methodology resulting standardized health index in the various countries of the world allows you to define the country implementing an effective management strategy in the health sector. The leading positions belong to the countries where the state health policy has shown its greatest efficiency. This technique can be used not only for point scoring result of a standardized health index in the world, but also to assess in a particular country.

  20. Author-paper affiliation network architecture influences the methodological quality of systematic reviews and meta-analyses of psoriasis.

    Directory of Open Access Journals (Sweden)

    Juan Luis Sanz-Cabanillas

    Full Text Available Moderate-to-severe psoriasis is associated with significant comorbidity, an impaired quality of life, and increased medical costs, including those associated with treatments. Systematic reviews (SRs and meta-analyses (MAs of randomized clinical trials are considered two of the best approaches to the summarization of high-quality evidence. However, methodological bias can reduce the validity of conclusions from these types of studies and subsequently impair the quality of decision making. As co-authorship is among the most well-documented forms of research collaboration, the present study aimed to explore whether authors' collaboration methods might influence the methodological quality of SRs and MAs of psoriasis. Methodological quality was assessed by two raters who extracted information from full articles. After calculating total and per-item Assessment of Multiple Systematic Reviews (AMSTAR scores, reviews were classified as low (0-4, medium (5-8, or high (9-11 quality. Article metadata and journal-related bibliometric indices were also obtained. A total of 741 authors from 520 different institutions and 32 countries published 220 reviews that were classified as high (17.2%, moderate (55%, or low (27.7% methodological quality. The high methodological quality subnetwork was larger but had a lower connection density than the low and moderate methodological quality subnetworks; specifically, the former contained relatively fewer nodes (authors and reviews, reviews by authors, and collaborators per author. Furthermore, the high methodological quality subnetwork was highly compartmentalized, with several modules representing few poorly interconnected communities. In conclusion, structural differences in author-paper affiliation network may influence the methodological quality of SRs and MAs on psoriasis. As the author-paper affiliation network structure affects study quality in this research field, authors who maintain an appropriate balance

  1. APPLICATION OF LOT QUALITY ASSURANCE SAMPLING FOR ASSESSING DISEASE CONTROL PROGRAMMES - EXAMINATION OF SOME METHODOLOGICAL ISSUES

    OpenAIRE

    T. R. RAMESH RAO

    2011-01-01

    Lot Quality Assurance Sampling (LQAS), a statistical tool in industrial setup, has been in use since 1980 for monitoring and evaluation of programs on disease control / immunization status among children / health workers performance in health system. While conducting LQAS in the field, there are occasions, even after due care of design, there are practical and methodological issues to be addressed before it is recommended for implementation and intervention. LQAS is applied under the assumpti...

  2. Quality assurance and quality control methodologies used within the austrian UV monitoring network

    International Nuclear Information System (INIS)

    Mario, B.

    2004-01-01

    The Austrian UVB monitoring network is operational since 1997. Nine detectors for measuring erythemally weighted solar UV irradiance are distributed over Austria in order to cover the main populated areas as well as different levels of altitude. The detectors are calibrated to indicate the UV-Index, the internationally agreed unit for erythemally weighted solar UV irradiance. Calibration is carried out in the laboratory for determination of spectral sensitivity of each detector, and under the sun for absolute comparison with a well-calibrated, double-monochromator spectro-radiometer. For the conversion from detector-weighted units to erythemally weighted units a lookup table is used, which is calculated using a radiative transfer model and which reflects the dependence of the conversion on the solar zenith angle and total ozone content of the atmosphere. The uncertainty of the calibration is about ±7%, dominated by the uncertainty of the calibration lamp for the spectro-radiometer (±4%). The long-term stability of this type of detectors has been found to be not satisfactory. Therefore, routinely every year all detectors are completely re-calibrated. Variations of the calibration factors up to ±10% are found. Thus, during routine operation, several measures take place for quality control. The measured data are compared to results of model calculations with a radiative transfer model, where clear sky and an aerosol-free atmosphere are assumed. At each site, the UV data are also compared with data from a co-located pyrano-meter measuring total solar irradiance. These two radiation quantities are well correlated, especially on clear days and when the ozone content is taken into account. If suspicious measurements are found for one detector in the network, a well-calibrated travelling reference detector of the same type is set up side-by-side, allowing the identification of relative differences of ∼3%. If necessary, a recalibration is carried out. As the main aim

  3. A methodology to improve higher education quality using the quality function deployment and analytic hierarchy process

    NARCIS (Netherlands)

    Raharjo, H.; Xie, M.; Goh, T.N.; Brombacher, A.C.

    2007-01-01

    In order to formulate an effective strategic plan in a customer-driven education context, it is important to recognize who the customers are and what they want. Using Quality Function Deployment (QFD), this information can be translated into strategies to achieve customer satisfaction. Since the

  4. The Methodological Approaches to Formation of the Internal System of Quality of Education of Higher Education Institution

    Directory of Open Access Journals (Sweden)

    Doronin Stepan A.

    2017-12-01

    Full Text Available The necessity of creation of a national conception of formation of the internal system of quality assurance of higher education institutions with obligatory introduction of methodological approach in its structure is substantiated; the variant of its terminological provision with clarification of the content of concepts of «quality of education», «internal system of quality of education», «methodological approach» is proposed; positioning of the approach in the system of other standard scientific instruments (method, methodology, program, algorithm is done; arguments for the orientation of the methodology of formation of the internal system of quality assurance of higher education institutions towards the socio-cultural model of paradigm are provided; a hierarchical classification of methodological approaches with allocation of the philosophical, scientific, concrete-scientific, technological levels and the characteristics of their purpose and contents is presented.

  5. The trials methodological research agenda: results from a priority setting exercise

    Science.gov (United States)

    2014-01-01

    Background Research into the methods used in the design, conduct, analysis, and reporting of clinical trials is essential to ensure that effective methods are available and that clinical decisions made using results from trials are based on the best available evidence, which is reliable and robust. Methods An on-line Delphi survey of 48 UK Clinical Research Collaboration registered Clinical Trials Units (CTUs) was undertaken. During round one, CTU Directors were asked to identify important topics that require methodological research. During round two, their opinion about the level of importance of each topic was recorded, and during round three, they were asked to review the group’s average opinion and revise their previous opinion if appropriate. Direct reminders were sent to maximise the number of responses at each round. Results are summarised using descriptive methods. Results Forty one (85%) CTU Directors responded to at least one round of the Delphi process: 25 (52%) responded in round one, 32 (67%) responded in round two, 24 (50%) responded in round three. There were only 12 (25%) who responded to all three rounds and 18 (38%) who responded to both rounds two and three. Consensus was achieved amongst CTU Directors that the top three priorities for trials methodological research were ‘Research into methods to boost recruitment in trials’ (considered the highest priority), ‘Methods to minimise attrition’ and ‘Choosing appropriate outcomes to measure’. Fifty other topics were included in the list of priorities and consensus was reached that two topics, ‘Radiotherapy study designs’ and ‘Low carbon trials’, were not priorities. Conclusions This priority setting exercise has identified the research topics felt to be most important to the key stakeholder group of Directors of UKCRC registered CTUs. The use of robust methodology to identify these priorities will help ensure that this work informs the trials methodological research agenda, with

  6. Quality at the source (QATS) system design under six sigma methodology

    Energy Technology Data Exchange (ETDEWEB)

    Aguirre, F; Ballasteros, I; Maricalva, J [Emperesa Nacional del Uranio, S.A. (ENUSA), Nuclear Fuel Manufacturing Plant, Juzbado, Salamanca (Spain)

    2000-07-01

    One of the main objectives in the manufacturing of fuel assemblies, is to fulfill the customer expectations with a product that assures its reliability during its stay in the NPP. By mean of the QATS System design under 6-Sigma methodology, all the customer requirements are included in the product specifications and drawings. Product characteristics and process variables are classified and process capability is evaluated. All this information permits to identify CTQ's (Critical to Quality) product characteristics and process variables, and to define a quality system (QATS) based in the process and on-line characteristics control handled by the manufacturing workers. At the end, this system ensures a continuous product quality improvement, and a strong commitment with the customer requirements. (author)

  7. Quality at the source (QATS) system design under six sigma methodology

    International Nuclear Information System (INIS)

    Aguirre, F.; Ballasteros, I.; Maricalva, J.

    2000-01-01

    One of the main objectives in the manufacturing of fuel assemblies, is to fulfill the customer expectations with a product that assures its reliability during its stay in the NPP. By mean of the QATS System design under 6-Sigma methodology, all the customer requirements are included in the product specifications and drawings. Product characteristics and process variables are classified and process capability is evaluated. All this information permits to identify CTQ's (Critical to Quality) product characteristics and process variables, and to define a quality system (QATS) based in the process and on-line characteristics control handled by the manufacturing workers. At the end, this system ensures a continuous product quality improvement, and a strong commitment with the customer requirements. (author)

  8. [Needs assessment to improve the applicability and methodological quality of a German S3 guideline].

    Science.gov (United States)

    Burckhardt, Marion; Hoffmann, Cristina; Nink-Grebe, Brigitte; Sänger, Sylvia

    2018-04-01

    Clinical practice guidelines can change the practice in healthcare only if their recommendations are implemented in a comprehensive way. The German S3 guideline "Local Therapy of Chronic Wounds in Patients with Peripheral Vascular Disease, Chronic Venous Insufficiency, and Diabetes" will be updated in 2017. The emphasis here is on the guideline's validity, user-friendliness and implementation into practice. Therefore, the aim was to identify the improvements required in regard to the guideline's methods and content presentation. The methodological approach used was the critical appraisal of the guideline according to established quality criteria and an additional stakeholder survey. Both were conducted between August and November 2016. The guideline and its related documents were reviewed independently by two researchers according to the criteria of the "Appraisal of Guidelines for Research and Evaluation" (AGREE-II). Published reviews and peer reviews by external experts and organisations were also taken into account. For the stakeholder survey, a questionnaire with open questions was distributed by e-mail and via the Internet to health professionals and organisations involved in the care of patients with leg ulcers in Germany. The questions were aimed at amendments and new topics based on the stakeholders' experience in inpatient and outpatient care. In addition, the survey focused on gathering suggestions to improve the applicability of the guideline. Suggested new topics and amendments were summarised thematically. The stakeholders' suggestions to improve the applicability, the results of the critical appraisal and the relevant aspects of the external reviews were then summarised according to the AGREE-II domains and presented in a cause and effect diagram. 17 questionnaires (out of 864 sent out by e-mail) were returned. Due to high practice relevance, the stakeholders suggested an expansion of the inclusion criteria to patients with infected wounds and

  9. The reporting characteristics and methodological quality of Cochrane reviews about health policy research.

    Science.gov (United States)

    Xiu-xia, Li; Ya, Zheng; Yao-long, Chen; Ke-hu, Yang; Zong-jiu, Zhang

    2015-04-01

    The systematic review has increasingly become a popular tool for researching health policy. However, due to the complexity and diversity in the health policy research, it has also encountered more challenges. We set out the Cochrane reviews on health policy research as a representative to provide the first examination of epidemiological and descriptive characteristics as well as the compliance of methodological quality with the AMSTAR. 99 reviews were included by inclusion criteria, 73% of which were Implementation Strategies, 15% were Financial Arrangements and 12% were Governance Arrangements; involved Public Health (34%), Theoretical Exploration (18%), Hospital Management (17%), Medical Insurance (12%), Pharmaceutical Policy (9%), Community Health (7%) and Rural Health (2%). Only 39% conducted meta-analysis, and 49% reported being updates, and none was rated low methodological quality. Our research reveals that the quantity and quality of the evidence should be improved, especially Financial Arrangements and Governance Arrangements involved Rural Health, Health Care Reform and Health Equity, etc. And the reliability of AMSTAR needs to be tested in larger range in this field. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  10. Methodological review of the quality of reach out and read: does it "work"?

    Science.gov (United States)

    Yeager Pelatti, Christina; Pentimonti, Jill M; Justice, Laura M

    2014-04-01

    A considerable percentage of American children and adults fail to learn adequate literacy skills and read below a third grade level. Shared book reading is perhaps the single most important activity to prepare young children for success in reading. The primary objective of this manuscript was to critically review the methodological quality of Read Out and Read (ROR), a clinically based literacy program/intervention that teaches parents strategies to incorporate while sharing books with children as a method of preventing reading difficulties and academic struggles. A PubMed search was conducted. Articles that met three criteria were considered. First, the study must be clinically based and include parent contact with a pediatrician. Second, parental counseling ("anticipatory guidance") about the importance of parent-child book reading must be included. Third, only experimental or quasi-experimental studies were included; no additional criteria were used. Published articles from any year and peer-reviewed journal were considered. Study quality was determined using a modified version of the Downs and Black (1998) checklist assessing four categories: (1) Reporting, (2) External Validity, (3) Internal Validity-Bias, and (4) Internal Validity-Confounding. We were also interested in whether quality differed based on study design, children's age, sample size, and study outcome. Eleven studies met the inclusion criteria. The overall quality of evidence was variable across all studies; Reporting and External Validity categories were relatively strong while methodological concerns were found in the area of internal validity. Quality scores differed on the four study characteristics. Implications related to clinical practice and future studies are discussed.

  11. Methodological quality of meta-analyses on treatments for chronic obstructive pulmonary disease: a cross-sectional study using the AMSTAR (Assessing the Methodological Quality of Systematic Reviews) tool.

    Science.gov (United States)

    Ho, Robin S T; Wu, Xinyin; Yuan, Jinqiu; Liu, Siya; Lai, Xin; Wong, Samuel Y S; Chung, Vincent C H

    2015-01-08

    Meta-analysis (MA) of randomised trials is considered to be one of the best approaches for summarising high-quality evidence on the efficacy and safety of treatments. However, methodological flaws in MAs can reduce the validity of conclusions, subsequently impairing the quality of decision making. To assess the methodological quality of MAs on COPD treatments. A cross-sectional study on MAs of COPD trials. MAs published during 2000-2013 were sampled from the Cochrane Database of Systematic Reviews and Database of Abstracts of Reviews of Effect. Methodological quality was assessed using the validated AMSTAR (Assessing the Methodological Quality of Systematic Reviews) tool. Seventy-nine MAs were sampled. Only 18% considered the scientific quality of primary studies when formulating conclusions and 49% used appropriate meta-analytic methods to combine findings. The problems were particularly acute among MAs on pharmacological treatments. In 48% of MAs the authors did not report conflict of interest. Fifty-eight percent reported harmful effects of treatment. Publication bias was not assessed in 65% of MAs, and only 10% had searched non-English databases. The methodological quality of the included MAs was disappointing. Consideration of scientific quality when formulating conclusions should be made explicit. Future MAs should improve on reporting conflict of interest and harm, assessment of publication bias, prevention of language bias and use of appropriate meta-analytic methods.

  12. Methodology and results of risk assessment of interconnections within the JET active gas handling system

    International Nuclear Information System (INIS)

    Ballantyne, P.R.; Bell, A.C.; Konstantellos, A.; Hemmerich, J.L.

    1992-01-01

    The Joint European Torus (JET) Active Gas Handling System (AGHS) is a complex interconnection of numerous subsystems. While individual subsystems were assessed for their risk of operation, an assessment of the effects of inadvertent interconnections was needed. A systematic method to document the assessment was devised to ease the assessment of complex plant and was applied to the AGHS. The methodology, application to AGHS, the four critical issues and required plant modifications as a result of this assessment are briefly discussed in this paper

  13. Application of Six Sigma Using DMAIC Methodology in the Process of Product Quality Control in Metallurgical Operation

    Directory of Open Access Journals (Sweden)

    Girmanová Lenka

    2017-12-01

    Full Text Available The Six Sigma DMAIC can be considered a guide for problem solving and product or process improvement. The majority of companies start to implement Six Sigma using the DMAIC methodology. The paper deals with application of Six Sigma using the DMAIC methodology in the process of product quality control. The case study is oriented on the field of metallurgical operations. The goal of the Six Sigma project was to ensure the required metallurgic product quality and to avoid an increase in internal costs associated with poor product quality. In this case study, a variety of tools and techniques like flow chart, histogram, Pareto diagram, analysis of FMEA (Failure Mode and Effect Analysis data, cause and effect diagram, logical analysis was used. The Sigma level has improved by approximately 13%. The achieved improvements have helped to reduce the quantity of defective products and the processing costs (technology for re-adjusting. Benefits resulting from the DMAIC implementation can be divided into three levels: the qualitative, economic and safety level.

  14. [Assessment of the methodological quality of theses submitted to the Faculty of Medicine Fez].

    Science.gov (United States)

    Boly, A; Tachfouti, N; Zohoungbogbo, I S S; Achhab, Y El; Nejjari, C

    2014-06-09

    A thesis in medicine is a scientific work which allows a medical student to acquire a Doctor of Medicine degree. It is therefore recommended that theses presented by students fulfill essential methodological criteria in order to obtain scientifically credible results and recommendations. The aim of this study was to assess the methodology of thesis presented to the Faculty of Medicine in Fez in 2008. We developed an evaluation table containing questions on the different sections of the IMRAD structure on which these theses were based and we estimated the proportion of theses that conformed to each criterion. There were 160 theses on various specialties presented in 2008. The majority of the theses (79.3%) were case series. Research questions were clearly expressed in 62.0% but the primary objectives were pertinent in only 52.0%. Our study shows that there were important deficiencies in the methodological rigor of the theses and very little representation of the theses in publications.

  15. Water Quality Research Program: Development of Unstructured Grid Linkage Methodology and Software for CE-QUAL-ICM

    National Research Council Canada - National Science Library

    Chapman, Raymond

    1997-01-01

    This study was conducted for the purpose of developing a methodology and associated software for linking hydrodynamic output from the RMAlO finite element model to the CE-QUAL-ICM finite volume water quality model...

  16. Quality of Open Education and MOOCs. MOOQ Workshop Results

    OpenAIRE

    Stracke, Christian M.; Tan, Esther

    2017-01-01

    Stracke, C. M., & Tan, E. (2017, 13 September). Quality of Open Education and MOOCs. MOOQ Workshop Results at 12th EC-TEL Conference, Tallinn, Estonia. More information about the Workshop online: http://mooc-quality.eu/events/openedu4all-on-open-education-at-ec-tel-2017

  17. How methodological issues affect the energy indicator results for different electricity generation technologies

    International Nuclear Information System (INIS)

    Modahl, Ingunn Saur; Raadal, Hanne Lerche; Gagnon, Luc; Bakken, Tor Haakon

    2013-01-01

    The aim of this paper is to improve the basis for the comparison of energy products. The paper will discuss important methodological issues with regard to various energy indicators and it will, by means of a few selected energy indicators, show examples of results for hydropower, wind power and electricity from biomass, gas and coal. Lastly it will suggest methods to achieve results which are more consistent when comparing electricity production technologies. In general, methodological issues can affect the results of life cycle assessments. In this paper, the authors have focused on the effect of system boundaries for energy indicators and found that the internal ranking of cases within one electricity generation technology is dependent on the indicator used. These variations do not, however, alter the general ranking of the major technologies studied. The authors suggest that future assessments should focus on a smaller set of indicators: the Cumulative Energy Demand (CED), which is the most “universal” indicator, Energy Payback Ratio (EPR) for assessment of upstream activities, and a suggested “Cumulative Fossil Energy Demand” (CFED) for resource depletion assessments. There is also a need for stricter standardisation and increased transparency in the assessment of energy products. - Highlights: • There is a need for stricter standardisation of energy performance assessments. • System boundaries for renewable sources should be harmonised. • One should focus on a smaller set of indicators. CED should be included

  18. The results of a quality-control programme in mammography

    International Nuclear Information System (INIS)

    Ramsdale, M.L.; Hiles, P.A.

    1989-01-01

    With the introduction of a breast screening programme in the UK, quality assurance in mammography is of paramount importance in assuring optimum imaging performance with low dose. Quality control checks are an essential part of the quality-assurance system. A quality-control programme at a breast screening clinic is described. Daily checks include film sensitometry for X-ray processor control and radiography of a lucite phantom to monitor the consistency of the X-ray machine automatic exposure control. Weekly checks include additional measurements on the performance of the automatic exposure control for different breast thickness and an overall assessment of image quality using a prototype mammography test phantom. The test phantom measures low-contrast sensitivity, high-contrast resolution and small-detail visibility. The results of the quality-control programme are presented with particular attention paid to tolerances and limiting values. (author)

  19. The HAZOP methodology applied to the study of the quality and the productivity

    International Nuclear Information System (INIS)

    Angel G, J.C.

    1996-01-01

    This article makes reference to an adaptation of the method HAZOP, used in Administration of Risks, to the study and solution of problems related with the quality and the productivity of matters cousins, processes, products and services. The described methodology, it is based in the definition of, intentions, or objectives for each part of the process, sub-process, product or service, with the purpose of finding, deviations, or problems of quality or productivity with the use of words g uide . It thinks about that each deviation should be analyzed for the determination of its causes and consequences, with the purpose of defining the corrective pertinent actions. The work of interdisciplinary groups intends as an unavoidable requirement, the same as the will of its members to make the things better every day

  20. Evaluation of the coat quality of sustained release pellets by individual pellet dissolution methodology.

    Science.gov (United States)

    Xu, Min; Liew, Celine Valeria; Heng, Paul Wan Sia

    2015-01-15

    This study explored the application of 400-DS dissolution apparatus 7 for individual pellet dissolution methodology by a design of experiment approach and compared its capability with that of the USP dissolution apparatus 1 and 2 for differentiating the coat quality of sustained release pellets. Drug loaded pellets were prepared by extrusion-spheronization from powder blends comprising 50%, w/w metformin, 25%, w/w microcrystalline cellulose and 25%, w/w lactose, and then coated with ethyl cellulose to produce sustained release pellets with 8% and 10%, w/w coat weight gains. Various pellet properties were investigated, including cumulative drug release behaviours of ensemble and individual pellets. When USP dissolution apparatus 1 and 2 were used for drug release study of the sustained release pellets prepared, floating and clumping of pellets were observed and confounded the release profiles of the ensemble pellets. Hence, the release profiles obtained did not characterize the actual drug release from individual pellet and the applicability of USP dissolution apparatus 1 and 2 to evaluate the coat quality of sustained release pellets was limited. The cumulative release profile of individual pellet using the 400-DS dissolution apparatus 7 was found to be more precise at distinguishing differences in the applied coat quality. The dip speed and dip interval of the reciprocating holder were critical operational parameters of 400-DS dissolution apparatus 7 that affected the drug release rate of a sustained release pellet during the individual dissolution study. The individual dissolution methodology using the 400-DS dissolution apparatus 7 is a promising technique to evaluate the individual pellet coat quality without the influence of confounding factors such as pellet floating and clumping observed during drug release test with dissolution apparatus 1 and 2, as well as to facilitate the elucidation of the actual drug release mechanism conferred by the applied sustained

  1. Results from CrIS-ATMS Obtained Using the AIRS Science Team Retrieval Methodology

    Science.gov (United States)

    Susskind, Joel; Kouvaris, Louis C.; Iredell, Lena

    2013-01-01

    which significantly improved results of AIRS Version-6. Version-5.70 CrIS/ATMS temperature profile and surface skin temperature retrievals are of very good quality, and are better than AIRS Version-5 retrievals, but are still significantly poorer than those of AIRS Version-6. CrIS/ATMS retrievals should improve when a Neural-Net start-up system is ready for use. We also examined CrIS/ATMS retrievals generated by NOAA using their NUCAPS retrieval algorithm, which is based on earlier versions of the AIRS Science Team retrieval algorithms. We show that the NUCAPS algorithm as currently configured is not well suited for climate monitoring purposes.

  2. Methodological Quality of Systematic Reviews Published in the Urological Literature from 1998 to 2012.

    Science.gov (United States)

    Corbyons, Katherine; Han, Julia; Neuberger, Molly M; Dahm, Philipp

    2015-11-01

    Systematic reviews synthesize the current best evidence to address a clinical question. Given the growing emphasis on evidence-based clinical practice, systematic reviews are being increasingly sought after and published. We previously reported limitations in the methodological quality of 57 individual systematic reviews published from 1998 to 2008. We provide an update to our previous study, adding systematic reviews published from 2009 to 2012. We systematically searched PubMed® and hand searched the table of contents of 4 major urological journals to identify systematic reviews related to questions of prevention and therapy. Two independent reviewers with prior formal evidence-based medicine training assessed the methodological quality using the validated 11-point AMSTAR (A Measurement Tool to Assess Systematic Reviews) instrument. We performed predefined statistical hypothesis testing for differences by publication period (1998 to 2008 vs 2009 to 2012) and journal of publication. We performed statistical testing using SPSS®, version 23.0 with a 2-sided α of 0.05 using the Student t-test, ANOVA and the chi-square test. A total of 113 systematic reviews published from 2009 to 2012 met study inclusion criteria. The most common topics were oncology (44 reviews or 38.9%), voiding dysfunction (26 or 23.0%) and stones/endourology (13 or 11.5%). The largest contributor was European Urology (46 reviews or 40.7%), followed by BJU International (31 or 27.4%) and The Journal of Urology® (22 or 19.5%). The mean ± SD AMSTAR score for the 2009 to 2012 period was 5.3 ± 2.3 compared to 4.8 ± 2.0 for 1998 to 2008 with a mean difference of 0.5 (95% CI 0.2 to 1.2, p = 0.133). While the number of systematic reviews published in the urological literature has increased substantially, the methodological quality of these studies remains suboptimal. Systematic review authors and editors should make every effort to adhere to well established methodological standards to enhance

  3. Interfacing systems loss of coolant accident (ISLOCA) pressure capacity methodology and Davis-Besse results

    International Nuclear Information System (INIS)

    Wesley, D.A.

    1991-01-01

    A loss of coolant accident resulting from the overpressurization by reactor coolant fluid of a system designed for low-pressure, low-temperature service has been identified as a potential contributor to nuclear power plant risk. In this paper, the methodology developed to assess the probability of failure as a function of internal pressure is presented, and sample results developed for the controlling failure modes and locations of four fluid systems at the Davis-Besse Plant are shown. Included in this evaluation are the tanks, heat exchangers, filters, pumps, valves, and flanged connections for each system. The variability in the probability of failure is included, and the estimated leak rates or leak areas are given for the controlling modes of failure. For this evaluation, all failures are based on quasistatic pressures since the probability of dynamic effects resulting from such causes as water hammer have been initially judged to be negligible for the Davis-Besse plant ISLOCA

  4. First Italian intercomparison on methodologies for dose assessment from internal contamination. Results and perspectives

    International Nuclear Information System (INIS)

    Castellani, C.M.; Battisti, P.; Tarroni, G.

    1998-01-01

    In the frame of the MIDIA activities (coordination of whole body counters operating in Italy) an intercomparison on dose evaluation methods was promoted and carried out between October 1995 and March 1996 by 5 WBC centres. The main results related to the estimation of Intake and effective dose equivalent on the four case studies are reported. A comparison with European preliminary results is also presented. Finally perspectives related to the quality assurance of internal dosimetry estimates are indicated [it

  5. Use of Proteomic Methodology in Optimization of Processing and Quality Control of Food of Animal Origin

    Directory of Open Access Journals (Sweden)

    Dajana Gašo-Sokač

    2011-01-01

    Full Text Available Food of animal origin, namely meat, seafood, milk and milk products, is the main protein source in human nutrition. These types of food are very complex mixtures that contain proteins and other components, and proteomic techniques enable simultaneous study of several hundred up to several thousand proteins. The use of proteomic methodology for quality control and quality assessment in production as well as for the optimization and development of new manufacturing processes is presented. Newly developed, faster and more selective methods for sample preparation followed by more sensitive mass spectrometry for identification of less abundant proteins are discussed. These techniques will help to understand variations in production, and to find markers for food quality criteria. Furthermore, biologically active peptides in food of animal origin have recently been the focus of proteomic and peptidomic investigations. Isolation and production of biologically active proteins and peptides, including the low abundance ones, will also be a focus of future research. The use of proteomics, peptidomics and metabonomics for the determination of product quality and the detection of adulterations in meat production, seafood identification and in the production of milk and milk products is also discussed.

  6. Evaluation of the quality of the environmental participation: A methodological proposal

    International Nuclear Information System (INIS)

    Zuluaga M, Clara; Carmona M, Sergio Ivan

    2004-01-01

    The advances in the way to sustainability are inseparable to the achievement in the citizenship construction, because the citizen condition is only realized in the proactive compromise with the territorial themes, the environmental management effectiveness requests high quality in their participative processes; therefore, pertinent tools are required to know and to appraise these processes. The goodness of these tools proceeds of their functionality in the knowledge of the participation quality purpose, that to environmental participative processes, is conceived in terms of legitimacy, representatively, democratization of the environmental knowledge, social cohesion, capacity of interlocution, and incidence in the decision making, with the coherent conceptual structure of these facets shapes the theoretical-methodological scaffolding that permits their joining in attributes, variables and indicators relatives to the characteristics of the participative planning processes, proper to account of the environmental participation quality. With the appraisal of the environmental participation quality in planning processes, supported in the integration of the constitutive attributes, is possible to obtain the index that facilitates their diagnostic and improvement

  7. Outcomes of Quality Assurance: A Discussion of Knowledge, Methodology and Validity

    Science.gov (United States)

    Stensaker, Bjorn

    2008-01-01

    A common characteristic in many quality assurance schemes around the world is their implicit and often narrowly formulated understanding of how organisational change is to take place as a result of the process. By identifying some of the underlying assumptions related to organisational change in current quality assurance schemes, the aim of this…

  8. External Costs and Benefits of Energy. Methodologies, Results and Effects on Renewable Energies Competitivity

    International Nuclear Information System (INIS)

    Saez, R.; Cabal, H.; Varela, M.

    1999-01-01

    This study attempts to give a summarised vision of the concept of eternality in energy production, the social and economic usefulness of its evaluation and consideration as support to the political decision-marking in environmental regulation matters, technologies selection of new plants, priorities establishment on energy plans, etc. More relevant environmental externalisation are described, as are the effects on the health, ecosystems, materials and climate, as well as some of the socioeconomic externalisation such as the employment, increase of the GDP and the reduction and depletion of energy resources. Different methodologies used during the last years have been reviewed as well as the principals resulted obtained in the most relevant studies accomplished internationally on this topic. Special mention has deserved the European study National Implementation of the Extern E Methodology in the EU . Results obtained are represented in Table 2 of this study. Also they are exposed, in a summarised way, the results obtained in the evaluation of environmental externalisation of the Spanish electrical system in function of the fuel cycle. In this last case the obtained results are more approximated since have been obtained by extrapolation from the obtained for ten representative plants geographically distributed trough the Peninsula. Finally it has been analysed the influence that the internalization of the external costs of conventional energies can have in the competitiveness and in te market of renewable energy, those which originate less environmental effects and therefore produce much smaller external costs. The mechanisms of internalization and the consideration on the convenience or not of their incorporation in the price of energy have been also discussed. (Author) 30 refs

  9. Patient-reported Outcomes in Randomised Controlled Trials of Prostate Cancer: Methodological Quality and Impact on Clinical Decision Making

    Science.gov (United States)

    Efficace, Fabio; Feuerstein, Michael; Fayers, Peter; Cafaro, Valentina; Eastham, James; Pusic, Andrea; Blazeby, Jane

    2014-01-01

    details to allow health policy makers and physicians to make critical appraisals of results. Patient summary In this report, we have investigated the methodological quality of PCa trials that have included a PRO assessment. We conclude that including PRO is critical to better evaluating the treatment effectiveness of new therapeutic approaches from the patient's perspective. Also, at least one-fifth of PRO RCTs in PCa have provided sufficient details to allow health policy makers and physicians to make a critical appraisal of results. PMID:24210091

  10. Sugar-Sweetened Beverages and Obesity Risk in Children and Adolescents: A Systematic Analysis on How Methodological Quality May Influence Conclusions.

    Science.gov (United States)

    Bucher Della Torre, Sophie; Keller, Amélie; Laure Depeyre, Jocelyne; Kruseman, Maaike

    2016-04-01

    In the context of a worldwide high prevalence of childhood obesity, the role of sugar-sweetened beverage (SSB) consumption as a cause of excess weight gain remains controversial. Conflicting results may be due to methodological issues in original studies and in reviews. The aim of this review was to systematically analyze the methodology of studies investigating the influence of SSB consumption on risk of obesity and obesity among children and adolescents, and the studies' ability to answer this research question. A systematic review of cohort and experimental studies published until December 2013 in peer-reviewed journals was performed on Medline, CINAHL, Web of Knowledge, and ClinicalTrials.gov. Studies investigating the influence of SSB consumption on risk of obesity and obesity among children and adolescents were included, and methodological quality to answer this question was assessed independently by two investigators using the Academy of Nutrition and Dietetics Quality Criteria Checklist. Among the 32 identified studies, nine had positive quality ratings and 23 studies had at least one major methodological issue. Main methodological issues included SSB definition and inadequate measurement of exposure. Studies with positive quality ratings found an association between SSB consumption and risk of obesity or obesity (n=5) (ie, when SSB consumption increased so did obesity) or mixed results (n=4). Studies with a neutral quality rating found a positive association (n=7), mixed results (n=9), or no association (n=7). The present review shows that the majority of studies with strong methodology indicated a positive association between SSB consumption and risk of obesity or obesity, especially among overweight children. In addition, study findings highlight the need for the careful and precise measurement of the consumption of SSBs and of important confounders. Copyright © 2016 Academy of Nutrition and Dietetics. Published by Elsevier Inc. All rights reserved.

  11. Development of a quality management system for borehole investigations. (1) Quality assurance and quality control methodology for hydraulic packer testing

    International Nuclear Information System (INIS)

    Takeuchi, Shinji; Kunimaru, Takanori; Ota, Kunio; Frieg, Bernd

    2011-01-01

    A quality assurance and quality control (QA/QC) system for the hydraulic packer tests has been established based on the surface-based investigations at JAEA's underground research laboratories in Mizunami and Horonobe. The established QA/QC system covers field investigations (data acquisition) and data analysis. For the field investigations, the adopted procedure is selection of a test section based on a detail fluid logging and checking with tally list, followed by inspection of test tools such as pressure transducers and shut-in valves, etc., test method selection using a 'sequential hydraulic test' for deciding appropriate method, and finally data quality confirmation by pressure changes and derivatives on a log-log plots during testing. Test event logs should also be described during testing for traceability. For the test data analysis, a quick analysis for rough estimation of hydraulic parameters, and a detailed analysis using type curve and/or numerical analyses are conducted stepwise. The established QA/QC system has been applied to the recent borehole investigations and its efficiency has been confirmed. (author)

  12. Assessment of quality of measurement results in interlaboratory comparisons

    International Nuclear Information System (INIS)

    Rosskopfova, O.; Matel, L.; Rajec, P.

    2009-01-01

    Testing laboratory accredited according to ISO/IEC 17025:2005 has to ensure the quality of their results. Important aspect of correct evaluation of the result is the accuracy and uncertainty. Requirement of ISO/IEC 17025:2005 is the accredited laboratories to express their results with the corresponding uncertainty. Participation of laboratories in interlaboratory comparisons provides objective evidence of the level of reliability and quality of their results. Thereby the competency of accredited laboratories verified, including the verification of the declared measurement uncertainty. Some interlaboratory comparisons in which took participation the Testing Laboratory of Radiochemical Analysis (LARCHA) are presented.

  13. СONTENTS OF THE METHODOLOGICAL AND TECHNOLOGICAL SUPPORT OF THE EDUCATION QUALITY MANAGEMENT INFORMATION SYSTEM FOR FUTURE ECONOMISTS

    Directory of Open Access Journals (Sweden)

    Kostiantyn S. Khoruzhyi

    2014-12-01

    Full Text Available In the article, the content and nature of organizational activities in scope of methodological and technological support of the education quality management information system (EQMIS for future economists are described. The content of the organizational activities for the implementation of methodological and technological support of EQMIS for future economists includes four stages (preparatory, instructional/adaptational, methodological/basic, as well as experimental/evaluational and contains a set of methodological and technological measures for each of the stages of the EQMIS implementation. A study of the pedagogical impact of the proposed methodology of using EQMIS in the formation of professional competence of economics students was also conducted. The main stages, methods and sequence of implementation arrangements for the methodological and technological support of EQMIS are defined.

  14. The results of a quality-control programme in mammography

    International Nuclear Information System (INIS)

    Ramsdale, M.L.; Hiles, P.A.

    1989-01-01

    A quality-control programme at a breast screening clinic is described. Daily checks include film sensitometry for X-ray processor control and radiography of a lucite phantom to monitor the consistency of the X-ray machine automatic exposure control. Weekly checks include additional measurements on the performance of the automatic exposure control for different breast thickness and an overall assessment of image quality using a prototype mammography test phantom. The test phantom measures low-contrast sensitivity, high-control resolution and small-detail visibility. The results of the quality-control programme are presented with particular attention paid to tolerances and limiting values. (author)

  15. Virtual enterprise architecture and methodology - Initial results from the Globeman21 project

    DEFF Research Database (Denmark)

    Vesterager, Johan; Larsen, Lars Bjørn; Gobbi, Chiara

    1999-01-01

    This paper will focus on presenting the initial results from the IMS project Globeman21 regarding generic models for Extended Enterprise Management (EEM). In particular the paper outlines a proposed architecture for the creation of virtual enterprises, industrial requirements regarding the generic...... models, terminology for describing extended enterprises, and initial considerations regarding a methodology for EEM. Globeman21 see the extended enterprise as a concept covering the totality of different concepts dealing with the expansion or extension of enterprise activities. One way of realising...... the concept of extended enterprise is through the creation of virtual enterprise, based on a more or less formalised network. This approach is the basis for the development of the generic EEM model within Globeman21....

  16. Car-borne prospecting methodology. First results from the Cuenca del Nordeste (Uruguay)

    International Nuclear Information System (INIS)

    Goso, H.; Spoturno, J.; Preciozzi, F.

    1976-01-01

    The paper reports on a prospecting procedure used in Uruguay for the selection of areas of interest and on the first results obtained in the Cuenca del Nordeste (North-East Basin). The methodology developed (preliminary radiometric investigation) consists of four successive stages: compilation of material; radiometric survey; statistical analysis; revision of anomalies. The compilation of material has the aim of obtaining geological and cartographic data and of laying out the network of tracks of the area to be prospected. The radiometric survey provides data by means of a car-borne recording scintillometer, together with geological information necessary for preparing the geological map. By statistical analysis of the results it is possible to define and quantify various types of anomalies in a simple manner. Use of a log-normal model yielded a highly logical and coherent approximation in the treatment of the data obtained, and a classification of the defined anomalies in order of importance. Anomaly revision is carried out on first and second order anomalies, and on those of the third order deemed to be significant. This methodology has been developed and is in use on sedimentary formations of the Devonian, Gondwana and Cretaceous, where there are various problems presented by the overburden and the grid size ranges between 1 km and 4-8 km 2 . In the particular case of the Cuenca del Nordeste (Gondwana), with no background of uranium mineralization, it was possible to select a zone of some 1000 km 2 in the San Gregorio-Tres Islas formation with a view to carrying out more detailed work. (author)

  17. [What is the methodological quality of articles on therapeutic procedures published in Cirugía Española?].

    Science.gov (United States)

    Manterola, Carlos; Busquets, Juli; Pascual, Marta; Grande, Luis

    2006-02-01

    The aim of this study was to determine the methodological quality of articles on therapeutic procedures published in Cirugía Española and to study its association with the publication year, center, and subject-matter. A bibliometric study that included all articles on therapeutic procedures published in Cirugía Española between 2001 and 2004 was performed. All kinds of clinical designs were considered, excluding editorials, review articles, letters to editor, and experimental studies. The variables analyzed were: year of publication, center, design, and methodological quality. Methodological quality was determined by a valid and reliable scale. Descriptive statistics (calculation of means, standard deviation and medians) and analytical statistics (Pearson's chi2, nonparametric, ANOVA and Bonferroni tests) were used. A total of 244 articles were studied (197 case series [81%], 28 cohort studies [12%], 17 clinical trials [7%], 1 cross sectional study and 1 case-control study [0.8%]). The studies were performed mainly in Catalonia and Murcia (22% and 16%, respectively). The most frequent subject areas were soft tissue and hepatobiliopancreatic surgery (23% and 19%, respectively). The mean and median of the methodological quality score calculated for the entire series was 10.2 +/- 3.9 points and 9.5 points, respectively. Methodological quality significantly increased by publication year (p < 0.001). An association between methodological quality and subject area was observed but no association was detected with the center performing the study. The methodological quality of articles on therapeutic procedures published in Cirugía Española between 2001 and 2004 is low. However, a statistically significant trend toward improvement was observed.

  18. New Brunswick air quality monitoring results for the year 2000

    International Nuclear Information System (INIS)

    Hughes, R.

    2002-01-01

    Monitoring data for air quality in New Brunswick in 2000 is presented in this document. Designed for the general public, it summarizes the air quality results for 2000 and focuses on air quality assessment as it relates to existing air quality standards and objectives. The report also contains the long term trend data for representative sites. The New Brunswick Air Quality Regulation of the Clean Air Act specifies the air quality standards applicable for carbon monoxide, sulphur dioxide, hydrogen sulphide, nitrogen dioxide and total suspended particulate. The monitoring was conducted at 58 sites in 8 regional monitoring networks throughout the province. Thirteen additional sites were selected for the measurement of acid rain. Despite the fact that no standards were in effect in 2000 in New Brunswick for several substances, including inhalable particulate matter, ground-level ozone, volatile organic compounds, selected semi-volatile organic compounds, trace elements in particulate matter and mercury in air and precipitation, their levels were measured at some locations. The results indicate that emissions trends, variations in industrial output, changing process or emission control technologies, and weather conditions throughout the year explain most of the variations in results between regions. As a rule, compliance with standards is good. Acid rain continued to impact, especially in the southwestern districts of the province. Since 1996, the levels of mercury in precipitation has slightly declined. 39 refs., 43 figs

  19. Methodological quality of diagnostic accuracy studies on non-invasive coronary CT angiography: influence of QUADAS (Quality Assessment of Diagnostic Accuracy Studies included in systematic reviews) items on sensitivity and specificity

    Energy Technology Data Exchange (ETDEWEB)

    Schueler, Sabine; Walther, Stefan; Schuetz, Georg M. [Humboldt-Universitaet zu Berlin, Freie Universitaet Berlin, Charite Medical School, Department of Radiology, Berlin (Germany); Schlattmann, Peter [University Hospital of Friedrich Schiller University Jena, Department of Medical Statistics, Informatics, and Documentation, Jena (Germany); Dewey, Marc [Humboldt-Universitaet zu Berlin, Freie Universitaet Berlin, Charite Medical School, Department of Radiology, Berlin (Germany); Charite, Institut fuer Radiologie, Berlin (Germany)

    2013-06-15

    To evaluate the methodological quality of diagnostic accuracy studies on coronary computed tomography (CT) angiography using the QUADAS (Quality Assessment of Diagnostic Accuracy Studies included in systematic reviews) tool. Each QUADAS item was individually defined to adapt it to the special requirements of studies on coronary CT angiography. Two independent investigators analysed 118 studies using 12 QUADAS items. Meta-regression and pooled analyses were performed to identify possible effects of methodological quality items on estimates of diagnostic accuracy. The overall methodological quality of coronary CT studies was merely moderate. They fulfilled a median of 7.5 out of 12 items. Only 9 of the 118 studies fulfilled more than 75 % of possible QUADAS items. One QUADAS item (''Uninterpretable Results'') showed a significant influence (P = 0.02) on estimates of diagnostic accuracy with ''no fulfilment'' increasing specificity from 86 to 90 %. Furthermore, pooled analysis revealed that each QUADAS item that is not fulfilled has the potential to change estimates of diagnostic accuracy. The methodological quality of studies investigating the diagnostic accuracy of non-invasive coronary CT is only moderate and was found to affect the sensitivity and specificity. An improvement is highly desirable because good methodology is crucial for adequately assessing imaging technologies. (orig.)

  20. Methodological quality of diagnostic accuracy studies on non-invasive coronary CT angiography: influence of QUADAS (Quality Assessment of Diagnostic Accuracy Studies included in systematic reviews) items on sensitivity and specificity

    International Nuclear Information System (INIS)

    Schueler, Sabine; Walther, Stefan; Schuetz, Georg M.; Schlattmann, Peter; Dewey, Marc

    2013-01-01

    To evaluate the methodological quality of diagnostic accuracy studies on coronary computed tomography (CT) angiography using the QUADAS (Quality Assessment of Diagnostic Accuracy Studies included in systematic reviews) tool. Each QUADAS item was individually defined to adapt it to the special requirements of studies on coronary CT angiography. Two independent investigators analysed 118 studies using 12 QUADAS items. Meta-regression and pooled analyses were performed to identify possible effects of methodological quality items on estimates of diagnostic accuracy. The overall methodological quality of coronary CT studies was merely moderate. They fulfilled a median of 7.5 out of 12 items. Only 9 of the 118 studies fulfilled more than 75 % of possible QUADAS items. One QUADAS item (''Uninterpretable Results'') showed a significant influence (P = 0.02) on estimates of diagnostic accuracy with ''no fulfilment'' increasing specificity from 86 to 90 %. Furthermore, pooled analysis revealed that each QUADAS item that is not fulfilled has the potential to change estimates of diagnostic accuracy. The methodological quality of studies investigating the diagnostic accuracy of non-invasive coronary CT is only moderate and was found to affect the sensitivity and specificity. An improvement is highly desirable because good methodology is crucial for adequately assessing imaging technologies. (orig.)

  1. BWR stability analysis: methodology of the stability analysis and results of PSI for the NEA/NCR benchmark task

    International Nuclear Information System (INIS)

    Hennig, D.; Nechvatal, L.

    1996-09-01

    The report describes the PSI stability analysis methodology and the validation of this methodology based on the international OECD/NEA BWR stability benchmark task. In the frame of this work, the stability properties of some operation points of the NPP Ringhals 1 have been analysed and compared with the experimental results. (author) figs., tabs., 45 refs

  2. Comparison of methodologic quality and study/report characteristics between quantitative clinical nursing and nursing education research articles.

    Science.gov (United States)

    Schneider, Barbara St Pierre; Nicholas, Jennifer; Kurrus, Jeffrey E

    2013-01-01

    To compare the methodologic quality and study/report characteristics between quantitative clinical nursing and nursing education research articles. The methodologic quality of quantitative nursing education research needs to advance to a higher level. Clinical research can provide guidance for nursing education to reach this level. One hundred quantitative clinical research articles from-high impact journals published in 2007 and 37 education research articles from high impact journals published in 2006 to 2007 were chosen for analysis. Clinical articles had significantly higher quality scores than education articles in three domains: number of institutions studied, type of data, and outcomes. The findings indicate three ways in which nursing education researchers can strengthen the methodologic quality of their quantitative research. With this approach, greater funding may be secured for advancing the science of nursing education.

  3. A quality score for coronary artery tree extraction results

    Science.gov (United States)

    Cao, Qing; Broersen, Alexander; Kitslaar, Pieter H.; Lelieveldt, Boudewijn P. F.; Dijkstra, Jouke

    2018-02-01

    Coronary artery trees (CATs) are often extracted to aid the fully automatic analysis of coronary artery disease on coronary computed tomography angiography (CCTA) images. Automatically extracted CATs often miss some arteries or include wrong extractions which require manual corrections before performing successive steps. For analyzing a large number of datasets, a manual quality check of the extraction results is time-consuming. This paper presents a method to automatically calculate quality scores for extracted CATs in terms of clinical significance of the extracted arteries and the completeness of the extracted CAT. Both right dominant (RD) and left dominant (LD) anatomical statistical models are generated and exploited in developing the quality score. To automatically determine which model should be used, a dominance type detection method is also designed. Experiments are performed on the automatically extracted and manually refined CATs from 42 datasets to evaluate the proposed quality score. In 39 (92.9%) cases, the proposed method is able to measure the quality of the manually refined CATs with higher scores than the automatically extracted CATs. In a 100-point scale system, the average scores for automatically and manually refined CATs are 82.0 (+/-15.8) and 88.9 (+/-5.4) respectively. The proposed quality score will assist the automatic processing of the CAT extractions for large cohorts which contain both RD and LD cases. To the best of our knowledge, this is the first time that a general quality score for an extracted CAT is presented.

  4. Improved Temperature Sounding and Quality Control Methodology Using AIRS/AMSU Data: The AIRS Science Team Version 5 Retrieval Algorithm

    Science.gov (United States)

    Susskind, Joel; Blaisdell, John M.; Iredell, Lena; Keita, Fricky

    2009-01-01

    This paper describes the AIRS Science Team Version 5 retrieval algorithm in terms of its three most significant improvements over the methodology used in the AIRS Science Team Version 4 retrieval algorithm. Improved physics in Version 5 allows for use of AIRS clear column radiances in the entire 4.3 micron CO2 absorption band in the retrieval of temperature profiles T(p) during both day and night. Tropospheric sounding 15 micron CO2 observations are now used primarily in the generation of clear column radiances .R(sub i) for all channels. This new approach allows for the generation of more accurate values of .R(sub i) and T(p) under most cloud conditions. Secondly, Version 5 contains a new methodology to provide accurate case-by-case error estimates for retrieved geophysical parameters and for channel-by-channel clear column radiances. Thresholds of these error estimates are used in a new approach for Quality Control. Finally, Version 5 also contains for the first time an approach to provide AIRS soundings in partially cloudy conditions that does not require use of any microwave data. This new AIRS Only sounding methodology, referred to as AIRS Version 5 AO, was developed as a backup to AIRS Version 5 should the AMSU-A instrument fail. Results are shown comparing the relative performance of the AIRS Version 4, Version 5, and Version 5 AO for the single day, January 25, 2003. The Goddard DISC is now generating and distributing products derived using the AIRS Science Team Version 5 retrieval algorithm. This paper also described the Quality Control flags contained in the DISC AIRS/AMSU retrieval products and their intended use for scientific research purposes.

  5. Using Indigenist and Indigenous methodologies to connect to deeper understandings of Aboriginal and Torres Strait Islander peoples' quality of life.

    Science.gov (United States)

    Kite, Elaine; Davy, Carol

    2015-12-01

    The lack of a common description makes measuring the concept of quality of life (QoL) a challenge. Whether QoL incorporates broader social features or is attributed to health conditions, the diverse range of descriptions applied by various disciplines has resulted in a concept that is multidimensional and vague. The variety of theoretical conceptualisations of QoL confounds and confuses even the most astute. Measuring QoL in Aboriginal and Torres Strait Islander populations is even more challenging. Instruments commonly developed and used to measure QoL are often derived from research methodologies shaped by Western cultural perspectives. Often they are simply translated for use among culturally and linguistically diverse Aboriginal and Torres Strait Islander peoples. This has implications for Aboriginal and Torres Strait Islander populations whose perceptions of health are derived from within their specific cultures, value systems and ways of knowing and being. Interconnections and relationships between themselves, their communities, their environment and the natural and spiritual worlds are complex. The way in which their QoL is currently measured indicates that very little attention is given to the diversity of Aboriginal and Torres Strait Islander peoples' beliefs or the ways in which those beliefs shape or give structure and meaning to their health and their lives. The use of Indigenist or Indigenous methodologies in defining what Aboriginal and Torres Strait Islander peoples believe gives quality to their lives is imperative. These methodologies have the potential to increase the congruency between their perceptions of QoL and instruments to measure it.

  6. Investigation Of Infrared Drying Behaviour Of Spinach Leaves Using ANN Methodology And Dried Product Quality

    Directory of Open Access Journals (Sweden)

    Sarimeseli Ayse

    2015-12-01

    Full Text Available Effects of infrared power output and sample mass on drying behaviour, colour parameters, ascorbic acid degradation, rehydration characteristics and some sensory scores of spinach leaves were investigated. Within both of the range of the infrared power outputs, 300–500 W, and sample amounts, 15–60 g, moisture content of the leaves was reduced from 6.0 to 0.1±(0.01 kg water/kg dry base value. It was recorded that drying times of the spinach leaves varied between 3.5–10 min for constant sample amount, and 4–16.5 min for constant power output. Experimental drying data obtained were successfully investigated by using artificial neural network methodology. Some changes were recorded in the quality parameters of the dried leaves, and acceptable sensory scores for the dried leaves were observed in all of the experimental conditions.

  7. Environmental risk assessment of water quality in harbor areas: a new methodology applied to European ports.

    Science.gov (United States)

    Gómez, Aina G; Ondiviela, Bárbara; Puente, Araceli; Juanes, José A

    2015-05-15

    This work presents a standard and unified procedure for assessment of environmental risks at the contaminant source level in port aquatic systems. Using this method, port managers and local authorities will be able to hierarchically classify environmental hazards and proceed with the most suitable management actions. This procedure combines rigorously selected parameters and indicators to estimate the environmental risk of each contaminant source based on its probability, consequences and vulnerability. The spatio-temporal variability of multiple stressors (agents) and receptors (endpoints) is taken into account to provide accurate estimations for application of precisely defined measures. The developed methodology is tested on a wide range of different scenarios via application in six European ports. The validation process confirms its usefulness, versatility and adaptability as a management tool for port water quality in Europe and worldwide. Copyright © 2015 Elsevier Ltd. All rights reserved.

  8. Association between prospective registration and overall reporting and methodological quality of systematic reviews: a meta-epidemiological study.

    Science.gov (United States)

    Ge, Long; Tian, Jin-Hui; Li, Ya-Nan; Pan, Jia-Xue; Li, Ge; Wei, Dang; Xing, Xin; Pan, Bei; Chen, Yao-Long; Song, Fu-Jian; Yang, Ke-Hu

    2018-01-01

    The aim of this study was to investigate the differences in main characteristics, reporting and methodological quality between prospectively registered and nonregistered systematic reviews. PubMed was searched to identify systematic reviews of randomized controlled trials published in 2015 in English. After title and abstract screening, potentially relevant reviews were divided into three groups: registered non-Cochrane reviews, Cochrane reviews, and nonregistered reviews. For each group, random number tables were generated in Microsoft Excel, and the first 50 eligible studies from each group were randomly selected. Data of interest from systematic reviews were extracted. Regression analyses were conducted to explore the association between total Revised Assessment of Multiple Systematic Review (R-AMSTAR) or Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) scores and the selected characteristics of systematic reviews. The conducting and reporting of literature search in registered reviews were superior to nonregistered reviews. Differences in 9 of the 11 R-AMSTAR items were statistically significant between registered and nonregistered reviews. The total R-AMSTAR score of registered reviews was higher than nonregistered reviews [mean difference (MD) = 4.82, 95% confidence interval (CI): 3.70, 5.94]. Sensitivity analysis by excluding the registration-related item presented similar result (MD = 4.34, 95% CI: 3.28, 5.40). Total PRISMA scores of registered reviews were significantly higher than nonregistered reviews (all reviews: MD = 1.47, 95% CI: 0.64-2.30; non-Cochrane reviews: MD = 1.49, 95% CI: 0.56-2.42). However, the difference in the total PRISMA score was no longer statistically significant after excluding the item related to registration (item 5). Regression analyses showed similar results. Prospective registration may at least indirectly improve the overall methodological quality of systematic reviews, although its impact

  9. Quality assessment with the AGIR software results and experience

    International Nuclear Information System (INIS)

    Rauch, D.; Kotter, E.; Kurtz, C.; Schaefer, O.; Ehritt-Braun, C.; Burger, D.; Schaper, J.; Uhrmeister, P.

    2001-01-01

    Purpose: To evaluate whether a new software from the working group for interventional radiology (AGIR) is an appropriate tool for quality assurance in interventional radiology, and presentation of results acquired within the quality improvement process in 1999. Patients and methods: AGIR-defined parameters such as patient data, risk profile, given interventions as well as complications were registered by a recently developed software. Based on monthly data analyses, possible complications were identified and discussed in morbidity and mortality conferences. Results: 1014 interventions were performed in our institution in 1999. According to criteria established by AGIR, the complication rate was 2.7%. In addition and according to SCVIR criteria, complications were distinguished quantitatively in five classes and semiquantitatively in minor and major groups. The result was a minor complication rate of 1.8%, and a major rate of 0.9%. There were no cases of death associated with the intervention. Further strategies were developed in order to reduce the complication rate. Conclusion: Extensive quality assurance methods can be integrated in daily routine work. These methods lead to an intensive transparency of treatment results, and allow the implementation of continuous quality improvements. The development of the software is a first step in establishing a nation-wide quality assurance system. Nevertheless, modification and additional definition of the AGIR predefined parameters are required, for example, to avoid unnecessary procedures. (orig.) [de

  10. A Model of Risk Analysis in Analytical Methodology for Biopharmaceutical Quality Control.

    Science.gov (United States)

    Andrade, Cleyton Lage; Herrera, Miguel Angel De La O; Lemes, Elezer Monte Blanco

    2018-01-01

    One key quality control parameter for biopharmaceutical products is the analysis of residual cellular DNA. To determine small amounts of DNA (around 100 pg) that may be in a biologically derived drug substance, an analytical method should be sensitive, robust, reliable, and accurate. In principle, three techniques have the ability to measure residual cellular DNA: radioactive dot-blot, a type of hybridization; threshold analysis; and quantitative polymerase chain reaction. Quality risk management is a systematic process for evaluating, controlling, and reporting of risks that may affects method capabilities and supports a scientific and practical approach to decision making. This paper evaluates, by quality risk management, an alternative approach to assessing the performance risks associated with quality control methods used with biopharmaceuticals, using the tool hazard analysis and critical control points. This tool provides the possibility to find the steps in an analytical procedure with higher impact on method performance. By applying these principles to DNA analysis methods, we conclude that the radioactive dot-blot assay has the largest number of critical control points, followed by quantitative polymerase chain reaction, and threshold analysis. From the analysis of hazards (i.e., points of method failure) and the associated method procedure critical control points, we conclude that the analytical methodology with the lowest risk for performance failure for residual cellular DNA testing is quantitative polymerase chain reaction. LAY ABSTRACT: In order to mitigate the risk of adverse events by residual cellular DNA that is not completely cleared from downstream production processes, regulatory agencies have required the industry to guarantee a very low level of DNA in biologically derived pharmaceutical products. The technique historically used was radioactive blot hybridization. However, the technique is a challenging method to implement in a quality

  11. Quality benchmarking methodology: Case study of finance and culture industries in Latvia

    Directory of Open Access Journals (Sweden)

    Ieva Zemīte

    2011-01-01

    Full Text Available Political, socio-economic and cultural changes that have taken place in the world during the last years have influenced all the spheres. Constant improvements are necessary to sustain in rival and shrinking markets. This sets high quality standards for the service industries. Therefore it is important to conduct comparison of quality criteria to ascertain which practices are achieving superior performance levels. At present companies in Latvia do not carry out mutual benchmarking, and as a result of that do not know how they rank against their peers in terms of quality, as well as they do not see benefits in sharing of information and in benchmarking.The purpose of this paper is to determine the criteria of qualitative benchmarking, and to investigate the use of the benchmarking quality in service industries, particularly: finance and culture sectors in Latvia in order to determine the key driving factors of quality, to explore internal and foreign benchmarks, and to reveal the full potential of inputs’ reduction and efficiency growth for the aforementioned industries.Case study and other tools are used to define the readiness of the company for benchmarking. Certain key factors are examined for their impact on quality criteria. The results are based on the research conducted in professional associations in defined fields (insurance and theatre.Originality/value – this is the first study that adopts the benchmarking models for measuring quality criteria and readiness for mutual comparison in insurance and theatre industries in Latvia.

  12. Reducing DNACPR complaints to zero: designing and implementing a treatment escalation plan using quality improvement methodology.

    Science.gov (United States)

    Shermon, Elizabeth; Munglani, Laura; Oram, Sarah; William, Linda; Abel, Julian

    2017-01-01

    Do Not Attempt Resuscitation (DNAR)decisions have traditionally formed the basis of ceiling of care discussions. However, poor quality discussions can lead to high patient and relative dissatisfaction, generating hospital complaints. Treatment escalation plans (TEPs) aim to highlight the wider remit of treatment options with a focus on effective communication. We aimed to improve TEP discussions and documentation at Weston General Hospital by introducing a standardised form. We aimed to develop a TEP document to reduce resuscitation-related complaints by improving communication and documentation. Qualitative and quantitative data were collected over 2 years and used to develop plan-do-study-act (PDSA) cycles using quality improvement methodology. Main barriers to improvement included time constraints and clinician's resistance. Analysis of patient liaison services data showed a progressive reduction in complaints regarding resuscitation, with no complaints having been received for the final six months of the project. Through use of a standardised form including treatment prompts, the quality of discussions and plans improved. Qualitative feedback demonstrated increased patient and relative satisfaction. In addition, junior doctors report the plans are helpful when making out-of-hours decisions. Development of a user-friendly form to document patient-guided TEPs helped junior doctors to lead advanced care planning discussions. The use of PDSA cycles demonstrated improvement in the quality of forms, which in turn improved communication, documentation and satisfaction. Future developments could include involvement of specialist teams to ensure TEP forms remain relevant to all clinical areas. In addition, with widespread use of the TEP forms, the traditional tick-box DNAR could be replaced to focus on patient-led care planning.

  13. Childhood leukaemia near British nuclear installations: Methodological issues and recent results

    International Nuclear Information System (INIS)

    Bithell, J. F.; Keegan, T. J.; Kroll, M. E.; Murphy, M. F. G.; Vincent, T. J.

    2008-01-01

    In 2008, the German Childhood Cancer Registry published the results of the Kinderkrebs in der Umgebung von Kernkraftwerken (KiKK) study of childhood cancer and leukaemia around German nuclear power stations. The positive findings appeared to conflict with the results of a recent British analysis carried out by the Committee on Medical Aspects of Radiation in the Environment (COMARE), published in 2005. The present paper first describes the COMARE study, which was based on data from the National Registry of Children's Tumours (NRCT); in particular, the methodology used in this study is described. Although the results of the COMARE study were negative for childhood leukaemia, this apparent discrepancy could be accounted for by a number of differences in approach, especially those relating to the distances from the power stations and the ages of the children studied. The present study was designed to match the KiKK study as far as possible. The incidence observed (18 cases within 5 km against 14.58 expected, p = 0.21) was not significantly raised. The risk estimate for proximity in the regression fitted was actually negative, though the confidence intervals involved are so wide that the difference from that reported in the KiKK study is only marginally statistically significant (p = 0.063). (authors)

  14. The use of fracture mechanics methodologies for NDT results evaluation and comparison

    International Nuclear Information System (INIS)

    Reale, S.

    1995-01-01

    In the general frame of analysing the interactions amongst the information from non destructive evaluation (NDE) and the methodologies to assess the integrity of a defective structure (such as fracture mechanics), the aim of the paper is to analyse and compare, in terms of indices related to safety margins, NDE results from round robin testing trials to acheive assessments of capabilities and limitations.A structural integrity/fracture mechanics approach for evaluating and comparing results from non destructive techniques is presented. Safety factors can be associated to flaws detected and characterized by inspections (estimated flaws) and to flaws actually present (reference flaws). The mismatch between safety factors associated to estimated flaws and safety factors associated to reference flaws can be used to assess capabilities and limitations of procedures and techniques in use for inspections.As an example, to show how the above procedure is applied and its potential as a method of data evaluation and comparison, the NDE results produced by the PISC (project for the inspection of steel components) activity have been considered. (orig.)

  15. Vulnerability of sandy coasts to climate change and anthropic pressures: methodology and preliminary results

    Science.gov (United States)

    Idier, D.; Poumadère, M.; Vinchon, C.; Romieu, E.; Oliveros, C.

    2009-04-01

    medium-term (decades), whereas the space scales range from several tens of meters to several tens of kilometers. The project is based on the study of representative coastal units: 4 sites characterised by low-lying linear sandy beaches but different, representative, hydrodynamic and socio-economic environments. These sites are located in: Mediterranean Sea (Lido of Sète), Atlantic coast (Truc Vert beach and Noirmoutier island) and English channel coast (Est of Dunkerque). Each of these sites is studied following the same methodology, on both the physical and socio-economic dimensions, the aim being to identify vulnerability indicators regarding climate change and anthropic pressure. 2 - METHODOLOGY The work is based on the following methodology, for every site: 1) The compartments of the unit are defined: shoreface, coastline, backshore, hinterland, from a physical and socio-economical point of view. 2) The available data are analysed in order to provide some information on the present trend of the coastal unit, regarding climate change and anthropic pressure, but also to support the model validation. 3) The vulnerability is studied. On one hand, the socio-economic dimension is assessed and, in a risk governance perspective, stake holders are identified and involved. This part of the project combines the study of social perceptions of dangers along with a deliberative workshop. On the other hand, numerical models of the physical behaviour of shoreface and coastline are applied. The selected models cover a time scale from short-term (storm time scale) to long-term (decades). Then, vulnerability can be studied: the vulnerability of coast/beach is defined and studied based on in-situ observations and model results. Most of these models needs some forcing conditions (waves at the boundary of the computational domains for instance). The present day conditions can be potentially modified by climate change. However, the model and literature review on climate change show that

  16. Quality Control in Screening for Infectious Diseases at Blood Banks. Rationale and Methodology.

    Science.gov (United States)

    Sáez-Alquezar, Amadeo; Albajar-Viñas, Pedro; Guimarães, André Valpassos; Corrêa, José Abol

    2015-11-01

    Quality control procedures are indispensable to ensure the reliability of the results provided by laboratories responsible for serological screening in blood banks. International recommendations on systems of quality management classify as a top component the inclusion of two types of control: (a) internal quality control (IQC) and (b) external quality control (EQC). In EQC it is essential to have, at least, a monthly frequency of laboratory assessment. On the other hand, IQC involves the daily use of low-reactivity control sera, which should be systematically added in all run, carried out in the laboratory for each parameter. Through the IQC analysis some variations in the criteria of run acceptance and rejection may be revealed, but it is of paramount importance to ensure the previous definition of these criteria and even more importantly, the adherence to them; and that corresponds to the validation of analytical runs of each test. Since 2010 this has been, for instance, the experience of the PNCQ*, developing external quality control programmes on serology for blood banks. These programmes use samples of lyophilized sera well-characterized for the reactivity related to the parameters used for the serological screening of blood donors. The programmes have used blind panels of six samples for monthly assessments. In the last 50 assessments, which involved 68 blood banks in Brazil, a significant number of instances of non-compliance were observed in all monthly assessments. These results provide strong support to the recommendation of systematic monthly assessments. (*) National Quality Control Programme (PNCQ).

  17. QUALITY MANAGEMENT AND INTEGRATED TOTAL QUALITY IN SPANISH MINING: RESULTS OF AN EMPIRICAL STUDY

    OpenAIRE

    ESCANCIANO, CARMEN; IGLESIAS-RODRÍGUEZ, FRANCISCO-JAVIER

    2012-01-01

    This paper presents the results of an empirical study conducted in Spain among mining companies that hold ISO 9001 certification. This study aimed at reflecting upon quality management in Spanish mining; and discovering whether the certification of a quality management system provides companies with a framework for integrating total quality management with other management systems, such as environmental management or occupational health and safety management. En este artículo se presentan ...

  18. Multi-attribute Evaluation of Website Quality in E-business Using an Integrated Fuzzy AHPTOPSIS Methodology

    Directory of Open Access Journals (Sweden)

    Tolga Kaya

    2010-09-01

    Full Text Available Success of an e-business company is strongly associated with the relative quality of its website compared to that of its competitors. The purpose of this study is to propose a multi-attribute e-business website quality evaluation methodology based on a modified fuzzy TOPSIS approach. In the proposed methodology, weights of the evaluation criteria are generated by a fuzzy AHP procedure. In performance evaluation problems, the judgments of the experts may usually be vague in form. As fuzzy logic can successfully deal with this kind of uncertainty in human preferences, both classical TOPSIS and classical AHP procedures are implemented under fuzzy environment. The proposed TOPSIS-AHP methodology has successfully been applied to a multi-attribute website quality evaluation problem in Turkish e-business market. Nine sub-criteria under four main categories are used in the evaluation of the most popular e-business websites of Turkey. A sensitivity analysis is also provided.

  19. Global health trials methodological research agenda:results from a priority setting exercise

    OpenAIRE

    Blazeby, Jane; Nasser, Mona; Soares-Weiser, Karla; Sydes, Matthew R.; Zhang, Junhua; Williamson, Paula R

    2018-01-01

    BackgroundMethodological research into the design, conduct, analysis and reporting of trials is essential to optimise the process. UK specialists in the field have established a set of top priorities in aid of this research. These priorities however may not be reflected in the needs of similar research in low to middle income countries (LMICs) with different healthcare provision, resources and research infrastructure. The aim of the study was to identify the top priorities for methodological ...

  20. Methodology and main results of seismic source characterization for the PEGASOS Project, Switzerland

    International Nuclear Information System (INIS)

    Coppersmith, K. J.; Youngs, R. R.; Sprecher, Ch.

    2009-01-01

    Under the direction of the National Cooperative for the Disposal of Radioactive Waste (NAGRA), a probabilistic seismic hazard analysis was conducted for the Swiss nuclear power plant sites. The study has become known under the name 'PEGASOS Project'. This is the first of a group of papers in this volume that describes the seismic source characterization methodology and the main results of the project. A formal expert elicitation process was used, including dissemination of a comprehensive database, multiple workshops for identification and discussion of alternative models and interpretations, elicitation interviews, feedback to provide the experts with the implications of their preliminary assessments, and full documentation of the assessments. A number of innovative approaches to the seismic source characterization methodology were developed by four expert groups and implemented in the study. The identification of epistemic uncertainties and treatment using logic trees were important elements of the assessments. Relative to the assessment of the seismotectonic framework, the four expert teams identified similar main seismotectonic elements: the Rhine Graben, the Jura / Molasse regions, Helvetic and crystalline subdivisions of the Alps, and the southern Germany region. In defining seismic sources, the expert teams used a variety of approaches. These range from large regional source zones having spatially-smoothed seismicity to smaller local zones, to account for spatial variations in observed seismicity. All of the teams discussed the issue of identification of feature-specific seismic sources (i.e. individual mapped faults) as well as the potential reactivation of the boundary faults of the Permo-Carboniferous grabens. Other important seismic source definition elements are the specification of earthquake rupture dimensions and the earthquake depth distribution. Maximum earthquake magnitudes were assessed for each seismic source using approaches that consider the

  1. [sup 123]I-IBZM SPECT: Reconstruction methodology and results in Parkinsonism and dystonia

    Energy Technology Data Exchange (ETDEWEB)

    Berding, G [Abt. fuer Nuklearmedizin und Spezielle Biophysik, Medizinische Hochschule Hannover (Germany); Gratz, K F [Abt. fuer Nuklearmedizin und Spezielle Biophysik, Medizinische Hochschule Hannover (Germany); Kolbe, H [Neurologische Klinik mit Klinischer Neurophysiologie, Medizinische Hochschule Hannover (Germany); Meyer, G J [Abt. fuer Nuklearmedizin und Spezielle Biophysik, Medizinische Hochschule Hannover (Germany); Dengler, R [Neurologische Klinik mit Klinischer Neurophysiologie, Medizinische Hochschule Hannover (Germany); Knoop, B O [Abt. fuer Nuklearmesstechnik und Strahlenschutz, Medizinische Hochschule Hannover (Germany); Hundeshagen, H [Abt. fuer Nuklearmedizin und Spezielle Biophysik, Medizinische Hochschule Hannover (Germany)

    1994-10-01

    In 58 patients with Parkinsonism or dystonia striatal dopamine D[sub 2] receptors were investigated using [sup 123]I-iodobenzamide ([sup 123]I-IBZM) single-photon emission computed tomography (SPECT). The influence of SPECT reconstruction methodology on semiquantification and the clinical value of [sup 123]I-IBZM SPECT were evaluated. Delineation of the striatal uptake and striatum/frontal cortex (ST/FC) ratios were improved by the use of compensation procedures for scatter and attenuation as well as the choice of an adequate filter. Satisfactory results were achieved using a Metz prefilter with a comparatively high order number (i.e. high cut-off and low suppression of higher frequencies via roll-off). Regarding clinical diagnoses it was not possible to differentiate between advanced idiopathic Parkinson's disease (IP) and Parkinsonism of other aetiology (OP) on the basis of [sup 123]I-IBZM SPECT. But patients with IP and favourable response to L-Dopa showed significantly higher ST/FC ratios than those with fluctuating response. In patients with dystonia ST/FC ratios were significantly higher compared to patients with IP or OP. (orig.)

  2. Ethical challenges facing veterinary professionals in Ireland: results from Policy Delphi with vignette methodology

    Science.gov (United States)

    Magalhães-Sant'Ana, M.; More, S. J.; Morton, D. B.; Hanlon, A.

    2016-01-01

    Ethics is key to the integrity of the veterinary profession. Despite its importance, there is a lack of applied research on the range of ethical challenges faced by veterinarians. A three round Policy Delphi with vignette methodology was used to record the diversity of views on ethical challenges faced by veterinary professionals in Ireland. Forty experts, comprising veterinary practitioners, inspectors and nurses, accepted to participate. In round 1, twenty vignettes describing a variety of ethically challenging veterinary scenarios were ranked in terms of ethical acceptability, reputational risk and perceived standards of practice. Round 2 aimed at characterising challenges where future policy development or professional guidance was deemed to be needed. In round 3, possible solutions to key challenges were explored. Results suggest that current rules and regulations are insufficient to ensure best veterinary practices and that a collective approach is needed to harness workable solutions for the identified ethical challenges. Challenges pertaining mostly to the food chain seem to require enforcement measures whereas softer measures that promote professional discretion were preferred to address challenges dealing with veterinary clinical services. These findings can support veterinary representative bodies, advisory committees and regulatory authorities in their decision making, policy and regulation. PMID:27613779

  3. Methodology and results of the seismic probabilistic safety assessment of Krsko nuclear power plant

    International Nuclear Information System (INIS)

    Vermaut, M.K.; Monette, P.; Campbell, R.D.

    1995-01-01

    A seismic IPEEE (Individual Plant Examination for External Events) was performed for the Krsko plant. The methodology adopted is the seismic PSA (Probabilistic Safety Assessment). The Krsko NPP is located on a medium to high seismicity site. The PSA study described here includes all the steps in the PSA sequence, i.e. reassessment of the site hazard, calculation of plant structures response including soil-structure interaction, seismic plant walkdowns, probabilistic seismic fragility analysis of plant structures and components, and quantification of seismic core damage frequency (CDF). Also relay chatter analysis and soil stability studies were performed. The seismic PSA described here is limited to the analysis of CDF (level I PSA). The subsequent determination and quantification of plant damage states, containment behaviour and radioactive releases to the outside (level 2 PSA) have been performed for the Krsko NPP but are not further described in this paper. The results of the seismic PSA study indicate that, with some upgrades suggested by the PSA team, the seismic induced CDF is comparable to that of most US and Western Europe NPPs. (author)

  4. Results from power quality measurements in Germany - An overview

    Energy Technology Data Exchange (ETDEWEB)

    Gerdes, G.J.; Santjer, F. [German Wind Energy Inst, Wilhelmshaven (Germany)

    1996-12-31

    Grid interferences caused by wind turbines (WT) are getting a severe problem in Germany with the fast increasing number of installed turbines. The wind energy capacity was doubled annually in the past three years. The actual situation and the plannings for the next years will lead to a situation, where high wind energy penetration will exercise a big influence on the power and voltage quality of local utility networks. Measurements performed in Germany according to a national guideline show a big variety in power quality performance of WT`s, which does affect the requirements for grid connection and thus the economical situation of wind energy projects to a large extent. The results from more than 25 power quality measurements will be discussed in this paper. 5 refs., 5 figs., 1 tab.

  5. Monitoring changes in soil carbon resulting from intensive production, a non-traditional agricultural methodology.

    Energy Technology Data Exchange (ETDEWEB)

    Dwyer, Brian P.

    2013-03-01

    New Mexico State University and a group of New Mexico farmers are evaluating an innovative agricultural technique they call Intensive Production (IP). In contrast to conventional agricultural practice, IP uses intercropping, green fallowing, application of soil amendments and soil microbial inocula to sequester carbon as plant biomass, resulting in improved soil quality. Sandia National Laboratories role was to identify a non-invasive, cost effective technology to monitor soil carbon changes. A technological review indicated that Laser Induced Breakdown Spectroscopy (LIBS) best met the farmers objectives. Sandia partnered with Los Alamos National Laboratory (LANL) to analyze farmers test plots using a portable LIBS developed at LANL. Real-time LIBS field sample analysis was conducted and grab samples were collected for laboratory comparison. The field and laboratory results correlated well implying the strong potential for LIBS as an economical field scale analytical tool for analysis of elements such as carbon, nitrogen, and phosphate.

  6. Social exclusion in academia through biases in methodological quality evaluation: On the situation of women in science and philosophy.

    Science.gov (United States)

    Leuschner, Anna

    2015-12-01

    Empirical studies show that academia is socially exclusive. I argue that this social exclusion works, at least partly, through the systematic methodological disqualification of contributions from members of underrepresented social groups. As methodological quality criteria are underdetermined their interpretation and weighting can be biased with relation to gender, race, social background, etc. Such biased quality evaluation can take place on a local or global level. The current situation of women in academic philosophy illuminates this. I conclude that only mechanical solutions can effectively change the situation. Copyright © 2015 Elsevier Ltd. All rights reserved.

  7. Participant evaluation results for two indoor air quality studies

    International Nuclear Information System (INIS)

    Hawthorne, A.R.; Dudney, C.S.; Cohen, M.A.; Spengler, J.D.

    1987-01-01

    After two surveys for indoor air pollutants (radon and other chemicals) the homeowners were surveyed for their reactions. The results of these participant evaluation surveys, assuming that the participants that responded to the survey were representative, indicate that homeowners will accept a significant level of monitoring activity as part of an indoor air quality field study. Those participants completing surveys overwhelmingly enjoyed being in the studies and would do it again. We believe that the emphasis placed on positive homeowner interactions and efforts made to inform participants throughout our studies were positive factors in this result. There was no substantial differences noted in the responses between the 70-house study, which included a homeowner compensation payment of $100, and the 300-house study, which did not include a compensation payment. These results provide encouragement to conduct future complex, multipollutant indoor air quality studies when they are scientifically sound and cost effective

  8. Rating the methodological quality in systematic reviews of studies on measurement properties: a scoring system for the COSMIN checklist.

    Science.gov (United States)

    Terwee, Caroline B; Mokkink, Lidwine B; Knol, Dirk L; Ostelo, Raymond W J G; Bouter, Lex M; de Vet, Henrica C W

    2012-05-01

    The COSMIN checklist is a standardized tool for assessing the methodological quality of studies on measurement properties. It contains 9 boxes, each dealing with one measurement property, with 5-18 items per box about design aspects and statistical methods. Our aim was to develop a scoring system for the COSMIN checklist to calculate quality scores per measurement property when using the checklist in systematic reviews of measurement properties. The scoring system was developed based on discussions among experts and testing of the scoring system on 46 articles from a systematic review. Four response options were defined for each COSMIN item (excellent, good, fair, and poor). A quality score per measurement property is obtained by taking the lowest rating of any item in a box ("worst score counts"). Specific criteria for excellent, good, fair, and poor quality for each COSMIN item are described. In defining the criteria, the "worst score counts" algorithm was taken into consideration. This means that only fatal flaws were defined as poor quality. The scores of the 46 articles show how the scoring system can be used to provide an overview of the methodological quality of studies included in a systematic review of measurement properties. Based on experience in testing this scoring system on 46 articles, the COSMIN checklist with the proposed scoring system seems to be a useful tool for assessing the methodological quality of studies included in systematic reviews of measurement properties.

  9. Clinical practice guidelines and consensus statements in oncology--an assessment of their methodological quality.

    Directory of Open Access Journals (Sweden)

    Carmel Jacobs

    Full Text Available Consensus statements and clinical practice guidelines are widely available for enhancing the care of cancer patients. Despite subtle differences in their definition and purpose, these terms are often used interchangeably. We systematically assessed the methodological quality of consensus statements and clinical practice guidelines published in three commonly read, geographically diverse, cancer-specific journals. Methods Consensus statements and clinical practice guidelines published between January 2005 and September 2013 in Current Oncology, European Journal of Cancer and Journal of Clinical Oncology were evaluated. Each publication was assessed using the Appraisal of Guidelines for Research and Evaluation II (AGREE II rigour of development and editorial independence domains. For assessment of transparency of document development, 7 additional items were taken from the Institute of Medicine's standards for practice guidelines and the Journal of Clinical Oncology guidelines for authors of guidance documents.Consensus statements and clinical practice guidelines published between January 2005 and September 2013 in Current Oncology, European Journal of Cancer and Journal of Clinical Oncology were evaluated. Each publication was assessed using the Appraisal of Guidelines for Research and Evaluation II (AGREE II rigour of development and editorial independence domains. For assessment of transparency of document development, 7 additional items were taken from the Institute of Medicine's standards for practice guidelines and the Journal of Clinical Oncology guidelines for authors of guidance documents.Thirty-four consensus statements and 67 clinical practice guidelines were evaluated. The rigour of development score for consensus statements over the three journals was 32% lower than that of clinical practice guidelines. The editorial independence score was 15% lower for consensus statements than clinical practice guidelines. One journal scored

  10. Prevalence of high blood pressure in Brazilian adolescents and quality of the employed methodological procedures: systematic review

    Directory of Open Access Journals (Sweden)

    Marina Gabriella Pereira de Andrada Magalhães

    2013-12-01

    Full Text Available OBJECTIVE: To review the literature on studies that estimated the prevalence of high blood pressure (HBP or systemic arterial hypertension (SAH in Brazilian adolescents, considering the employed methodological procedures. METHODS: Bibliographical research of prevalence studies of HBP/SAH in adolescents from 1995 to 2010. The search was conducted in the electronic databases PubMed/Medline, Lilacs, SciELO, and Isi Adolec. The descriptors "hypertension", "BP", "teen", "students", "cross-sectional", "prevalence" and "Brazil" were used in Portuguese and English. Furthermore, a score ranging from 0 to 18 based on Recommendations for Blood Pressure Measurement in Humans and Experimental Animals and the VI Brazilian Guidelines of Hypertension was elaborated, in order to analyze the procedures used to measure BP in studies. RESULTS: Twenty-one articles were identified, mostly published in the last 10 years, and 90.5% were performed in school-based and regions of the Southeast, Northeast and South. The prevalence of HBP/SAH ranged from 2.5 to 30.9%. The score of the studies ranged from 0 to 16. A significant negative correlation (rho = -0.504; p = 0.020 was observed between the prevalence of HBP/SAH and the score of BP measurement quality. CONCLUSION: The great variability of PAE/SAH estimates appears to be influenced by methodological procedures used in the studies.

  11. Methodology and results of a space station education pilot programme in the primary school

    Science.gov (United States)

    Mirra, G.; Mirra, C.

    Potential users of the Space Station Freedom are now still in the Primary School. Subject studies 1 have shown that a robust familiarization programme has to be developed in order to increase public awareness on the microgravity environment and its capabilities to perform unique science. At the same time, several surveys 2 have demonstrated that elementary school students are showing the greatest interest and enthusiasm in space related activities among all school students. With these boundary conditions, a pilot programme, aimed at verifying the capabilities of young primary school pupils (aged between 10 and 12) in understanding why one performs research in space, has been conceived. In order to overcome the lack of space training of school teachers, an expert in space operations joined a group of elementary teachers to activate this program: merging the necessary didactic and technical capabilities. Consequently, the aim of the program becomes two folded: •generate critical thinking and problem solving capacities as well as inventiveness in children making them aware on the use of space to improve life on Earth. •identify the key issues for the definition of a robust space utilization educational programme. The programme has been managed by MARS Center. the Italian User Support Center for the Space Station utilization, and the institute "Speranzas" in the nearby of Naples, Italy. MARS Center, in particular, is responsible towards the national agency ASI, Agenzia Spaziale Italiana, of the execution of the promotional activity towards all the possible target groups: young students are among these groups. This programme started in late 1992 and is currently ongoing. The objective of this paper is to provide a description of the methodology and the reasons of such a programme with a snapshot on the preliminary results and future trends. Means used as supporting tools, such as films, posters and role plays are herein depicted as well as statistics on the pupils

  12. Comparison of tools for assessing the methodological quality of primary and secondary studies in health technology assessment reports in Germany

    Directory of Open Access Journals (Sweden)

    Walter, Ulla

    2010-01-01

    Full Text Available Health care policy background: Findings from scientific studies form the basis for evidence-based health policy decisions. Scientific background: Quality assessments to evaluate the credibility of study results are an essential part of health technology assessment reports and systematic reviews. Quality assessment tools (QAT for assessing the study quality examine to what extent study results are systematically distorted by confounding or bias (internal validity. The tools can be divided into checklists, scales and component ratings. Research questions: What QAT are available to assess the quality of interventional studies or studies in the field of health economics, how do they differ from each other and what conclusions can be drawn from these results for quality assessments? Methods: A systematic search of relevant databases from 1988 onwards is done, supplemented by screening of the references, of the HTA reports of the German Agency for Health Technology Assessment (DAHTA and an internet search. The selection of relevant literature, the data extraction and the quality assessment are carried out by two independent reviewers. The substantive elements of the QAT are extracted using a modified criteria list consisting of items and domains specific to randomized trials, observational studies, diagnostic studies, systematic reviews and health economic studies. Based on the number of covered items and domains, more and less comprehensive QAT are distinguished. In order to exchange experiences regarding problems in the practical application of tools, a workshop is hosted. Results: A total of eight systematic methodological reviews is identified as well as 147 QAT: 15 for systematic reviews, 80 for randomized trials, 30 for observational studies, 17 for diagnostic studies and 22 for health economic studies. The tools vary considerably with regard to the content, the performance and quality of operationalisation. Some tools do not only include the

  13. Methodological and Reporting Quality of Comparative Studies Evaluating Health-Related Quality of Life of Colorectal Cancer Patients and Controls: A Systematic Review.

    Science.gov (United States)

    Wong, Carlos K H; Guo, Vivian Y W; Chen, Jing; Lam, Cindy L K

    2016-11-01

    Health-related quality of life is an important outcome measure in patients with colorectal cancer. Comparison with normative data has been increasingly undertaken to assess the additional impact of colorectal cancer on health-related quality of life. This review aimed to critically appraise the methodological details and reporting characteristics of comparative studies evaluating differences in health-related quality of life between patients and controls. A systematic search of English-language literature published between January 1985 and May 2014 was conducted through a database search of PubMed, Web of Science, Embase, and Medline. Comparative studies reporting health-related quality-of-life outcomes among patients who have colorectal cancer and controls were selected. Methodological and reporting quality per comparison study was evaluated based on a 11-item methodological checklist proposed by Efficace in 2003 and a set of criteria predetermined by reviewers. Thirty-one comparative studies involving >10,000 patients and >10,000 controls were included. Twenty-three studies (74.2%) originated from European countries, with the largest number from the Netherlands (n = 6). Twenty-eight studies (90.3%) compared the health-related quality of life of patients with normative data published elsewhere, whereas the remaining studies recruited a group of patients who had colorectal cancer and a group of control patients within the same studies. The European Organisation for Research and Treatment of Cancer Quality-of-Life Questionnaire Core 30 was the most extensively used instrument (n = 16; 51.6%). Eight studies (25.8%) were classified as "probably robust" for clinical decision making according to the Efficace standard methodological checklist. Our further quality assessment revealed the lack of score differences reported (61.3%), contemporary comparisons (36.7%), statistical significance tested (38.7%), and matching of control group (58.1%), possibly leading to

  14. Quality control methodology for high-throughput protein-protein interaction screening.

    Science.gov (United States)

    Vazquez, Alexei; Rual, Jean-François; Venkatesan, Kavitha

    2011-01-01

    Protein-protein interactions are key to many aspects of the cell, including its cytoskeletal structure, the signaling processes in which it is involved, or its metabolism. Failure to form protein complexes or signaling cascades may sometimes translate into pathologic conditions such as cancer or neurodegenerative diseases. The set of all protein interactions between the proteins encoded by an organism constitutes its protein interaction network, representing a scaffold for biological function. Knowing the protein interaction network of an organism, combined with other sources of biological information, can unravel fundamental biological circuits and may help better understand the molecular basics of human diseases. The protein interaction network of an organism can be mapped by combining data obtained from both low-throughput screens, i.e., "one gene at a time" experiments and high-throughput screens, i.e., screens designed to interrogate large sets of proteins at once. In either case, quality controls are required to deal with the inherent imperfect nature of experimental assays. In this chapter, we discuss experimental and statistical methodologies to quantify error rates in high-throughput protein-protein interactions screens.

  15. Evaluation of methodologies for assessing the overall diet: dietary quality scores and dietary pattern analysis.

    Science.gov (United States)

    Ocké, Marga C

    2013-05-01

    This paper aims to describe different approaches for studying the overall diet with advantages and limitations. Studies of the overall diet have emerged because the relationship between dietary intake and health is very complex with all kinds of interactions. These cannot be captured well by studying single dietary components. Three main approaches to study the overall diet can be distinguished. The first method is researcher-defined scores or indices of diet quality. These are usually based on guidelines for a healthy diet or on diets known to be healthy. The second approach, using principal component or cluster analysis, is driven by the underlying dietary data. In principal component analysis, scales are derived based on the underlying relationships between food groups, whereas in cluster analysis, subgroups of the population are created with people that cluster together based on their dietary intake. A third approach includes methods that are driven by a combination of biological pathways and the underlying dietary data. Reduced rank regression defines linear combinations of food intakes that maximally explain nutrient intakes or intermediate markers of disease. Decision tree analysis identifies subgroups of a population whose members share dietary characteristics that influence (intermediate markers of) disease. It is concluded that all approaches have advantages and limitations and essentially answer different questions. The third approach is still more in an exploration phase, but seems to have great potential with complementary value. More insight into the utility of conducting studies on the overall diet can be gained if more attention is given to methodological issues.

  16. Comparison of tools for assessing the methodological quality of primary and secondary studies in health technology assessment reports in Germany.

    Science.gov (United States)

    Dreier, Maren; Borutta, Birgit; Stahmeyer, Jona; Krauth, Christian; Walter, Ulla

    2010-06-14

    HEALTH CARE POLICY BACKGROUND: Findings from scientific studies form the basis for evidence-based health policy decisions. Quality assessments to evaluate the credibility of study results are an essential part of health technology assessment reports and systematic reviews. Quality assessment tools (QAT) for assessing the study quality examine to what extent study results are systematically distorted by confounding or bias (internal validity). The tools can be divided into checklists, scales and component ratings. What QAT are available to assess the quality of interventional studies or studies in the field of health economics, how do they differ from each other and what conclusions can be drawn from these results for quality assessments? A systematic search of relevant databases from 1988 onwards is done, supplemented by screening of the references, of the HTA reports of the German Agency for Health Technology Assessment (DAHTA) and an internet search. The selection of relevant literature, the data extraction and the quality assessment are carried out by two independent reviewers. The substantive elements of the QAT are extracted using a modified criteria list consisting of items and domains specific to randomized trials, observational studies, diagnostic studies, systematic reviews and health economic studies. Based on the number of covered items and domains, more and less comprehensive QAT are distinguished. In order to exchange experiences regarding problems in the practical application of tools, a workshop is hosted. A total of eight systematic methodological reviews is identified as well as 147 QAT: 15 for systematic reviews, 80 for randomized trials, 30 for observational studies, 17 for diagnostic studies and 22 for health economic studies. The tools vary considerably with regard to the content, the performance and quality of operationalisation. Some tools do not only include the items of internal validity but also the items of quality of reporting and

  17. D4.1 Learning analytics: theoretical background, methodology and expected results

    NARCIS (Netherlands)

    Tammets, Kairit; Laanpere, Mart; Eradze, Maka; Brouns, Francis; Padrón-Nápoles, Carmen; De Rosa, Rosanna; Ferrari, Chiara

    2014-01-01

    The purpose of the EMMA project is to showcase excellence in innovative teaching methodologies and learning approaches through the large-scale piloting of MOOCs on different subjects. The main objectives related with the implementation of learning analytics in EMMa project are to: ● develop the

  18. Data fusion methodologies for food and beverage authentication and quality assessment – A review

    International Nuclear Information System (INIS)

    Borràs, Eva; Ferré, Joan; Boqué, Ricard; Mestres, Montserrat; Aceña, Laura; Busto, Olga

    2015-01-01

    The ever increasing interest of consumers for safety, authenticity and quality of food commodities has driven the attention towards the analytical techniques used for analyzing these commodities. In recent years, rapid and reliable sensor, spectroscopic and chromatographic techniques have emerged that, together with multivariate and multiway chemometrics, have improved the whole control process by reducing the time of analysis and providing more informative results. In this progression of more and better information, the combination (fusion) of outputs of different instrumental techniques has emerged as a means for increasing the reliability of classification or prediction of foodstuff specifications as compared to using a single analytical technique. Although promising results have been obtained in food and beverage authentication and quality assessment, the combination of data from several techniques is not straightforward and represents an important challenge for chemometricians. This review provides a general overview of data fusion strategies that have been used in the field of food and beverage authentication and quality assessment. - Highlights: • Multivariate data fusion is used in food authentication and quality assessment. • Data fusion approaches and their applications are reviewed. • Data preprocessing, variable selection and feature extraction are considered. • Model selection and validation are also considered.

  19. Data fusion methodologies for food and beverage authentication and quality assessment – A review

    Energy Technology Data Exchange (ETDEWEB)

    Borràs, Eva [iSens Group, Department of Analytical Chemistry and Organic Chemistry, Universitat Rovira i Virgili, Campus Sescelades, 43007 Tarragona (Spain); Ferré, Joan, E-mail: joan.ferre@urv.cat [Chemometrics, Qualimetrics and Nanosensors Group, Department of Analytical Chemistry and Organic Chemistry, Universitat Rovira i Virgili, Campus Sescelades, 43007 Tarragona (Spain); Boqué, Ricard [Chemometrics, Qualimetrics and Nanosensors Group, Department of Analytical Chemistry and Organic Chemistry, Universitat Rovira i Virgili, Campus Sescelades, 43007 Tarragona (Spain); Mestres, Montserrat; Aceña, Laura; Busto, Olga [iSens Group, Department of Analytical Chemistry and Organic Chemistry, Universitat Rovira i Virgili, Campus Sescelades, 43007 Tarragona (Spain)

    2015-09-03

    The ever increasing interest of consumers for safety, authenticity and quality of food commodities has driven the attention towards the analytical techniques used for analyzing these commodities. In recent years, rapid and reliable sensor, spectroscopic and chromatographic techniques have emerged that, together with multivariate and multiway chemometrics, have improved the whole control process by reducing the time of analysis and providing more informative results. In this progression of more and better information, the combination (fusion) of outputs of different instrumental techniques has emerged as a means for increasing the reliability of classification or prediction of foodstuff specifications as compared to using a single analytical technique. Although promising results have been obtained in food and beverage authentication and quality assessment, the combination of data from several techniques is not straightforward and represents an important challenge for chemometricians. This review provides a general overview of data fusion strategies that have been used in the field of food and beverage authentication and quality assessment. - Highlights: • Multivariate data fusion is used in food authentication and quality assessment. • Data fusion approaches and their applications are reviewed. • Data preprocessing, variable selection and feature extraction are considered. • Model selection and validation are also considered.

  20. 40 CFR Appendix D to Part 132 - Great Lakes Water Quality Initiative Methodology for the Development of Wildlife Criteria

    Science.gov (United States)

    2010-07-01

    ... Methodology for the Development of Wildlife Criteria D Appendix D to Part 132 Protection of Environment... Development of Wildlife Criteria Great Lakes States and Tribes shall adopt provisions consistent with (as protective as) this appendix. I. Introduction A. A Great Lakes Water Quality Wildlife Criterion (GLWC) is the...

  1. Review and evaluation of the methodological quality of the existing guidelines and recommendations for inherited neurometabolic disorders

    DEFF Research Database (Denmark)

    Cassis, Linda; Cortès-Saladelafont, Elisenda; Molero-Luis, Marta

    2015-01-01

    and timely treatments are often pivotal for the favorable course of the disease. Thus, the elaboration of new evidence-based recommendations for iNMD diagnosis and management is increasingly requested by health care professionals and patients, even though the methodological quality of existing guidelines...

  2. Rating the methodological quality in systematic reviews of studies on measurement properties: a scoring system for the COSMIN checklist

    NARCIS (Netherlands)

    Terwee, C.B.; Mokkink, L.B.; Knol, D.L.; Ostelo, R.W.J.G.; Bouter, L.M.; de Vet, H.C.W.

    2012-01-01

    Background: The COSMIN checklist is a standardized tool for assessing the methodological quality of studies on measurement properties. It contains 9 boxes, each dealing with one measurement property, with 5-18 items per box about design aspects and statistical methods. Our aim was to develop a

  3. Impact of methodology on the results of economic evaluations of varicella vaccination programs: is it important for decision-making?

    Directory of Open Access Journals (Sweden)

    Patrícia Coelho de Soárez

    2009-01-01

    Full Text Available This study aims to review the literature on economic evaluation of childhood varicella vaccination programs and to discuss how heterogeneity in methodological aspects and estimation of parameters can affect the studies' results. After applying the inclusion criteria, 27 studies published from 1980 to 2008 were analyzed in relation to methodological differences. There was great heterogeneity in the perspective adopted, evaluation of indirect costs, type of model used, modeling of the effect on herpes zoster, and estimation of vaccine price and efficacy parameters. The factor with the greatest impact on results was the inclusion of indirect costs, followed by the perspective adopted and vaccine price. The choice of a particular methodological aspect or parameter affected the studies' results and conclusions. It is essential that authors present these choices transparently so that users of economic evaluations understand the implications of such choices and the direction in which the results of the analysis were conducted.

  4. [Evolution of a quality assurance programme for physiotherapy schools - results of the first quality inspections].

    Science.gov (United States)

    Kainz, B; Schlag, B; Jäckel, W H

    2004-02-01

    In cooperation with the Hochrhein-Institute for Research in Rehabilitation (HRI), the Association for Assuring the Quality of Education in Physiotherapy Schools in Germany (ISQ) has developed a quality assurance programme for physiotherapy schools. It aims at assessing the quality of physiotherapy schools in Germany, and to award a quality seal based on compliance with defined criteria. First, a catalogue of quality features and criteria relevant for education in physiotherapy was developed. It is based on the analysis of questionnaires that had been sent to all German physiotherapy schools, to selected physiotherapists and leading physiotherapists in hospitals, to competent federal authorities, and to three school-classes with group discussions. The persons addressed named 360 different quality features. They were collected in a catalogue, revised in a multi-stage Delphi procedure, and approved consensually. The final criteria were transformed into basic quality requirements, and formulated as a check-list. Assessment of the quality features is carried out by trained visitors. In addition, the satisfaction of students is assessed with a questionnaire. The results of the interviews and the questionnaires are fed back to the schools in a quality report. Schools meeting all basic quality requirements are awarded the seal of quality. The seal is valid for three years. Since January 2003, this procedure is available for all schools in Germany. Until September 2002, a pretest of visitations and student questionnaires had been carried out with 31 member schools of the ISQ; according to the resulting quality reports, none of these schools would instantly be awarded the quality seal. In all, more than half of the schools do not meet 10 of the 42 basic criteria. Fundamental deficiencies have been found in the documentation pertaining to supervision of practical training. In terms of training, further training and professional development of their teachers and associated

  5. Tsunami vulnerability analysis in the coastal town of Catania, Sicily: methodology and results

    Science.gov (United States)

    Pagnoni, Gianluca; Tinti, Stefano; Gallazzi, Sara; Tonini, Roberto; Zaniboni, Filippo

    2010-05-01

    Catania lies on the eastern coast of Sicily and is one of the most important towns in Sicily as regards history, tourism and industry. Recent analyses conducted in the frame of the project TRANSFER have shown that it is exposed not only to tsunamis generated locally, but also to distant tsunamis generated in the western Hellenic arc. In the frame of the European project SCHEMA different scenarios covering local sources such as the 11 January 1693 event and the 1908 case as well as remote sources such as the 365 AD tsunami have been explored through numerical modelling in order to assess the vulnerability of the area to tsunami attacks. One of the primary outcomes of the scenario analysis is the quantification of the inundation zones (location, extension along the coast and landward). Taking the modelling results on flooding as input data, the analysis has focussed on the geomorphological characteristics of the coasts and on the buildings and infrastructure typology to make evaluation of the vulnerability level of the Catania area. The coast to the south of the harbour of Catania is low and characterized by a mild slope: topography reaches the altitude of 10 m between 300-750 m distance from the shoreline. Building density is low, and generally tourist structures prevail on residential houses. The zone north of the harbour is high-coast, with 10 m isoline usually close to the coastline, and little possibility for flood to penetrate deep inland. Here there are three small marinas with the corresponding services and infrastructure around, and the city quarters consists of residential buildings. Vulnerability assessment has been carried out by following the methodology developed by the SCHEMA consortium, distinguishing between primary (type and material) and secondary criteria (e.g. ground, age, foundation, orientation, etc.) for buildings, and by adopting a building damage matrix, basically depending on building type and water inundation depth. Data needed for such

  6. Quality Assessment of Studies Published in Open Access and Subscription Journals: Results of a Systematic Evaluation.

    Science.gov (United States)

    Pastorino, Roberta; Milovanovic, Sonja; Stojanovic, Jovana; Efremov, Ljupcho; Amore, Rosarita; Boccia, Stefania

    2016-01-01

    Along with the proliferation of Open Access (OA) publishing, the interest for comparing the scientific quality of studies published in OA journals versus subscription journals has also increased. With our study we aimed to compare the methodological quality and the quality of reporting of primary epidemiological studies and systematic reviews and meta-analyses published in OA and non-OA journals. In order to identify the studies to appraise, we listed all OA and non-OA journals which published in 2013 at least one primary epidemiologic study (case-control or cohort study design), and at least one systematic review or meta-analysis in the field of oncology. For the appraisal, we picked up the first studies published in 2013 with case-control or cohort study design from OA journals (Group A; n = 12), and in the same time period from non-OA journals (Group B; n = 26); the first systematic reviews and meta-analyses published in 2013 from OA journals (Group C; n = 15), and in the same time period from non-OA journals (Group D; n = 32). We evaluated the methodological quality of studies by assessing the compliance of case-control and cohort studies to Newcastle and Ottawa Scale (NOS) scale, and the compliance of systematic reviews and meta-analyses to Assessment of Multiple Systematic Reviews (AMSTAR) scale. The quality of reporting was assessed considering the adherence of case-control and cohort studies to STrengthening the Reporting of OBservational studies in Epidemiology (STROBE) checklist, and the adherence of systematic reviews and meta-analyses to Preferred Reporting Items for Systematic reviews and Meta-Analysis (PRISMA) checklist. Among case-control and cohort studies published in OA and non-OA journals, we did not observe significant differences in the median value of NOS score (Group A: 7 (IQR 7-8) versus Group B: 8 (7-9); p = 0.5) and in the adherence to STROBE checklist (Group A, 75% versus Group B, 80%; p = 0.1). The results did not change after adjustment

  7. A major advance in the quality of the training aimed at improving results

    International Nuclear Information System (INIS)

    Delgado, J. L.; Gonzalez Anez, F.

    2013-01-01

    Tecnatom has made in the last years several initiatives focused on improving quality and standards of training services with respect to processes,methodology and instructor qualification. Main areas of actuation are described in this article. (Author)

  8. Quality evaluation of health information system's architectures developed using the HIS-DF methodology.

    Science.gov (United States)

    López, Diego M; Blobel, Bernd; Gonzalez, Carolina

    2010-01-01

    Requirement analysis, design, implementation, evaluation, use, and maintenance of semantically interoperable Health Information Systems (HIS) have to be based on eHealth standards. HIS-DF is a comprehensive approach for HIS architectural development based on standard information models and vocabulary. The empirical validity of HIS-DF has not been demonstrated so far. Through an empirical experiment, the paper demonstrates that using HIS-DF and HL7 information models, semantic quality of HIS architecture can be improved, compared to architectures developed using traditional RUP process. Semantic quality of the architecture has been measured in terms of model's completeness and validity metrics. The experimental results demonstrated an increased completeness of 14.38% and an increased validity of 16.63% when using the HIS-DF and HL7 information models in a sample HIS development project. Quality assurance of the system architecture in earlier stages of HIS development presumes an increased quality of final HIS systems, which supposes an indirect impact on patient care.

  9. The Connections Between Firms’ Organisation Quality and their Business Results

    Directory of Open Access Journals (Sweden)

    Marko Pregeljc

    2012-11-01

    Full Text Available With classic statistical approaches and novel machine learning methods, we attempt to improve insight into the connections between the quality of an organisation of firms as a type of formal social unit and the business results of firms. The research used a data set with 72 extensive and very difficult-to-obtain assessments of the quality of an organisation (recorded only once 2007 and their business results, traced in four successive business years (2006–2009. We hypothesize that a causal relationship exists between the latter and the former. Only the final conclusions will be presented, together with some excerpts of the most interesting findings in the selected years of observation. A novel general explanation method from the computer science field of machine learning and data mining can be used to explain the influence of individual relevant organisational elements on the business results. Our findings confirm that traditional statistics and machine-learning approaches are successful at modelling this dependency relationship. Furthermore, the explanation of the influence of the organisational elements on the predicted business results provides insights that have meaningful scientific interpretations and proves the important meaning of good organisation for its firm.

  10. Load shape development for Swedish commercial and public buildings - methodologies and results

    Energy Technology Data Exchange (ETDEWEB)

    Noren, C.

    1999-06-01

    The knowledge concerning electricity consumption, and especially load demand, in Swedish commercial buildings is very limited. The current study deals with methods for electricity consumption indicator development and application of the different methodologies on measured data. Typical load shapes and consumption indicators are developed for four different types of commercial buildings: schools, hotels, grocery stores and department stores. Two different methodologies for consumption indicator development are presented and discussed. The influence on load demand from different factors such as, installations, outdoor temperature and building activities is studied. It is suggested that building floor area is not an accurate determinant of building electricity consumption and it is necessary to consider other factors as those just mentioned to understand commercial building electricity consumption. The application of the two methodologies on measured data shows that typical load shapes can be developed with reasonable accuracy. For most of the categories it is possible to use the typical load shapes for approximation of whole-building load shapes with error rates about 10-25% depending on day-type and building type. Comparisons of the developed load shapes with measured data show good agreement 49 refs, 22 figs, 3 tabs

  11. Quality of methodological reporting of randomized clinical trials of sodium-glucose cotransporter-2 (sglt2 inhibitors

    Directory of Open Access Journals (Sweden)

    Hadeel Alfahmi

    2017-01-01

    Full Text Available Sodium-glucose cotransporter-2 (SGLT2 inhibitors are a new class of medicines approved recently for the treatment of type 2 diabetes. To improve the quality of randomized clinical trial (RCT reports, the Consolidated Standards of Reporting Trials (CONSORT statement for methodological features was created. For achieving our objective in this study, we assessed the quality of methodological reporting of RCTs of SGLT2 inhibitors according to the 2010 CONSORT statement. We reviewed and analyzed the methodology of SGLT2 inhibitors RCTs that were approved by the Food & Drug Administration (FDA. Of the 27 trials, participants, eligibility criteria, and additional analyses were reported in 100% of the trials. In addition, trial design, interventions, and statistical methods were reported in 96.3% of the trials. Outcomes were reported in 93.6% of the trials. Settings were reported in 85.2% of the trials. Blinding and sample size were reported in 66.7 and 59.3% of the trials, respectively. Sequence allocation and the type of randomization were reported in 63 and 74.1% of the trials, respectively. Besides those, a few methodological items were inadequate in the trials. Allocation concealment was inadequate in most of the trials. It was reported only in 11.1% of the trials. The majority of RCTs have high percentage adherence for more than half of the methodological items of the 2010 CONSORT statement.

  12. ATLAS RPC Quality Assurance results at INFN Lecce

    CERN Document Server

    INSPIRE-00211509; Borjanovic, I.; Cataldi, G.; Cazzato, A.; Chiodini, G.; Coluccia, M. R.; Creti, P.; Gorini, E.; Grancagnolo, F.; Perrino, R.; Primavera, M.; Spagnolo, S.; Tassielli, G.; Ventura, A.

    2006-01-01

    The main results of the quality assurance tests performed on the Resistive Plate Chamber used by the ATLAS experiment at LHC as muon trigger chambers are reported and discussed. Since July 2004, about 270 RPC units has been certified at INFN Lecce site and delivered to CERN, for being integrated in the final muon station of the ATLAS barrel region. We show the key RPC characteristics which qualify the performance of this detector technology as muon trigger chamber in the harsh LHC enviroments. These are dark current, chamber efficiency, noise rate, gas volume tomography, and gas leakage.

  13. Development of a methodology for the analysis of the crystalline quality of single crystals

    International Nuclear Information System (INIS)

    Metairon, Sabrina

    1999-01-01

    This work aims to establish a methodology for the analysis of the crystalline quality of single crystals. It is shown in the work as from neutron diffraction tridimensional rocking curves it is possible to determine the intrinsic widths at half maximum of the crystalline domains of a crystal, as well as the relative intensities of such domains and the angular distances between them. The construction of contour maps, on the bases of the tridimensional curves, make easier the determination of the above characteristics. For the development of the method, tridimensional rocking curves (I x ω x χ) have been obtained with neutrons from a barium lithium fluoride (BaLiF 3 ) and an aluminum crystal. The intensity I was obtained as rocking curves around the ω axis, with the angle % varying in a convenient interval. The individual (I x ω) and (I x χ) curves, which constitute the tridimensional rocking curve, were fitted by Gaussians and, in continuation of the process, the instrumental broadenings in directions ω and χ were deconvoluted from them. The instrumental broadenings were obtained with perfect type lithium fluoride (LiF) single crystals in the form of rocking curves around the ω and χ axes. Due to an enhanced Lorentz factor in direction χ, the scale in this direction was 'shrunk' by a correction factor in order to make the widths at half maximum of domains equivalent to those found in direction co. The contour map constructed with the deconvoluted rocking curves for BaLiF 3 , showed the existence of a 'proximity effect' that occurs when the widths at half maximum of domains have values near the value of the instrumental broadening. The contour map constructed with the deconvoluted rocking curves for aluminum, showed five domains of the mosaic type. Such domains were characterized concerning the width at half maximum, relative intensity and distance between them. (author)

  14. Data fusion methodologies for food and beverage authentication and quality assessment - a review.

    Science.gov (United States)

    Borràs, Eva; Ferré, Joan; Boqué, Ricard; Mestres, Montserrat; Aceña, Laura; Busto, Olga

    2015-09-03

    The ever increasing interest of consumers for safety, authenticity and quality of food commodities has driven the attention towards the analytical techniques used for analyzing these commodities. In recent years, rapid and reliable sensor, spectroscopic and chromatographic techniques have emerged that, together with multivariate and multiway chemometrics, have improved the whole control process by reducing the time of analysis and providing more informative results. In this progression of more and better information, the combination (fusion) of outputs of different instrumental techniques has emerged as a means for increasing the reliability of classification or prediction of foodstuff specifications as compared to using a single analytical technique. Although promising results have been obtained in food and beverage authentication and quality assessment, the combination of data from several techniques is not straightforward and represents an important challenge for chemometricians. This review provides a general overview of data fusion strategies that have been used in the field of food and beverage authentication and quality assessment. Copyright © 2015 Elsevier B.V. All rights reserved.

  15. Results of pilot project on introducing quality control of mammographic equipment

    International Nuclear Information System (INIS)

    Vasileva, Zh.; Lichev, A.; Dimov, A.; Kostova, E.; Dimov, G.

    2003-01-01

    Objective:The results from a pilot project, realized in the framework of the PHARE Project 'Radiation Protection and Safety in Medical Use of the Ionizing Radiation'. The main goal of the project is the elaboration a quality control program for mammographic equipment and its implementation in 4 radiological units in the country. Another task is to examine the possibility for conducting a mammographic screening using this equipment. Material and methods: The developed quality control program has the following components: test parameters; criteria for intervention; minimal frequency of measurement. Methodologies for measurement of the parameters and assessment of the results in accordance with the European Protocol for physical and technical aspects of the mammographic screening. Standard protocols have been elaborated. Results: The quality program has been tested for three month at different hospitals. Conclusions: Optimization and strict control of the process of film development are needed. The exposure equipment. The quality control program should be implemented on all mammographic equipment in the country. For the performance of mammographic screening a strict selection of the equipment is necessary

  16. [Methodological quality evaluation of randomized controlled trials for traditional Chinese medicines for treatment of sub-health].

    Science.gov (United States)

    Zhao, Jun; Liao, Xing; Zhao, Hui; Li, Zhi-Geng; Wang, Nan-Yue; Wang, Li-Min

    2016-11-01

    To evaluate the methodological quality of the randomized controlled trials(RCTs) for traditional Chinese medicines for treatment of sub-health, in order to provide a scientific basis for the improvement of clinical trials and systematic review. Such databases as CNKI, CBM, VIP, Wanfang, EMbase, Medline, Clinical Trials, Web of Science and Cochrane Library were searched for RCTS for traditional Chinese medicines for treatment of sub-health between the time of establishment and February 29, 2016. Cochrane Handbook 5.1 was used to screen literatures and extract data, and CONSORT statement and CONSORT for traditional Chinese medicine statement were adopted as the basis for quality evaluation. Among the 72 RCTs included in this study, 67 (93.05%) trials described the inter-group baseline data comparability, 39(54.17%) trials described the unified diagnostic criteria, 28(38.89%) trials described the unified standards of efficacy, 4 (5.55%) trials mentioned the multi-center study, 19(26.38%) trials disclosed the random distribution method, 6(8.33%) trials used the random distribution concealment, 15(20.83%) trials adopted the method of blindness, 3(4.17%) study reported the sample size estimation in details, 5 (6.94%) trials showed a sample size of more than two hundred, 19(26.38%) trials reported the number of withdrawal, defluxion cases and those lost to follow-up, but only 2 trials adopted the ITT analysis,10(13.89%) trials reported the follow-up results, none of the trial reported the test registration and the test protocol, 48(66.7%) trials reported all of the indicators of expected outcomes, 26(36.11%) trials reported the adverse reactions and adverse events, and 4(5.56%) trials reported patient compliance. The overall quality of these randomized controlled trials for traditional Chinese medicines for treatment of sub-health is low, with methodological defects in different degrees. Therefore, it is still necessary to emphasize the correct application of principles

  17. Using Lean Six Sigma Methodology to Improve Quality of the Anesthesia Supply Chain in a Pediatric Hospital.

    Science.gov (United States)

    Roberts, Renée J; Wilson, Ashley E; Quezado, Zenaide

    2017-03-01

    Six Sigma and Lean methodologies are effective quality improvement tools in many health care settings. We applied the DMAIC methodology (define, measure, analyze, improve, control) to address deficiencies in our pediatric anesthesia supply chain. We defined supply chain problems by mapping existing processes and soliciting comments from those involved. We used daily distance walked by anesthesia technicians and number of callouts for missing supplies as measurements that we analyzed before and after implementing improvements (anesthesia cart redesign). We showed improvement in the metrics after those interventions were implemented, and those improvements were sustained and thus controlled 1 year after implementation.

  18. Calibration methodology application of kerma area product meters in situ: Preliminary results

    Science.gov (United States)

    Costa, N. A.; Potiens, M. P. A.

    2014-11-01

    The kerma-area product (KAP) is a useful quantity to establish the reference levels of conventional X-ray examinations. It can be obtained by measurements carried out with a KAP meter on a plane parallel transmission ionization chamber mounted on the X-ray system. A KAP meter can be calibrated in laboratory or in situ, where it is used. It is important to use one reference KAP meter in order to obtain reliable quantity of doses on the patient. The Patient Dose Calibrator (PDC) is a new equipment from Radcal that measures KAP. It was manufactured following the IEC 60580 recommendations, an international standard for KAP meters. This study had the aim to calibrate KAP meters using the PDC in situ. Previous studies and the quality control program of the PDC have shown that it has good function in characterization tests of dosimeters with ionization chamber and it also has low energy dependence. Three types of KAP meters were calibrated in four different diagnostic X-ray equipments. The voltages used in the two first calibrations were 50 kV, 70 kV, 100 kV and 120 kV. The other two used 50 kV, 70 kV and 90 kV. This was related to the equipments limitations. The field sizes used for the calibration were 10 cm, 20 cm and 30 cm. The calibrations were done in three different cities with the purpose to analyze the reproducibility of the PDC. The results gave the calibration coefficient for each KAP meter and showed that the PDC can be used as a reference instrument to calibrate clinical KAP meters.

  19. Multi-GNSS signal-in-space range error assessment - Methodology and results

    Science.gov (United States)

    Montenbruck, Oliver; Steigenberger, Peter; Hauschild, André

    2018-06-01

    The positioning accuracy of global and regional navigation satellite systems (GNSS/RNSS) depends on a variety of influence factors. For constellation-specific performance analyses it has become common practice to separate a geometry-related quality factor (the dilution of precision, DOP) from the measurement and modeling errors of the individual ranging measurements (known as user equivalent range error, UERE). The latter is further divided into user equipment errors and contributions related to the space and control segment. The present study reviews the fundamental concepts and underlying assumptions of signal-in-space range error (SISRE) analyses and presents a harmonized framework for multi-GNSS performance monitoring based on the comparison of broadcast and precise ephemerides. The implications of inconsistent geometric reference points, non-common time systems, and signal-specific range biases are analyzed, and strategies for coping with these issues in the definition and computation of SIS range errors are developed. The presented concepts are, furthermore, applied to current navigation satellite systems, and representative results are presented along with a discussion of constellation-specific problems in their determination. Based on data for the January to December 2017 time frame, representative global average root-mean-square (RMS) SISRE values of 0.2 m, 0.6 m, 1 m, and 2 m are obtained for Galileo, GPS, BeiDou-2, and GLONASS, respectively. Roughly two times larger values apply for the corresponding 95th-percentile values. Overall, the study contributes to a better understanding and harmonization of multi-GNSS SISRE analyses and their use as key performance indicators for the various constellations.

  20. Quality initiatives: improving patient flow for a bone densitometry practice: results from a Mayo Clinic radiology quality initiative.

    Science.gov (United States)

    Aakre, Kenneth T; Valley, Timothy B; O'Connor, Michael K

    2010-03-01

    Lean Six Sigma process improvement methodologies have been used in manufacturing for some time. However, Lean Six Sigma process improvement methodologies also are applicable to radiology as a way to identify opportunities for improvement in patient care delivery settings. A multidisciplinary team of physicians and staff conducted a 100-day quality improvement project with the guidance of a quality advisor. By using the framework of DMAIC (define, measure, analyze, improve, and control), time studies were performed for all aspects of patient and technologist involvement. From these studies, value stream maps for the current state and for the future were developed, and tests of change were implemented. Comprehensive value stream maps showed that before implementation of process changes, an average time of 20.95 minutes was required for completion of a bone densitometry study. Two process changes (ie, tests of change) were undertaken. First, the location for completion of a patient assessment form was moved from inside the imaging room to the waiting area, enabling patients to complete the form while waiting for the technologist. Second, the patient was instructed to sit in a waiting area immediately outside the imaging rooms, rather than in the main reception area, which is far removed from the imaging area. Realignment of these process steps, with reduced technologist travel distances, resulted in a 3-minute average decrease in the patient cycle time. This represented a 15% reduction in the initial patient cycle time with no change in staff or costs. Radiology process improvement projects can yield positive results despite small incremental changes.

  1. MODERN CONCEPTS OF THE SIX SIGMA METHODOLOGY FOR IMPROVING THE QUALITY

    Directory of Open Access Journals (Sweden)

    MARGARITA JANESKA

    2018-02-01

    Full Text Available Product quality is generally accepted as being crucial in today’s industrial business. The traditional aspects of product quality are connected to product design (translating customer demands into attractive features and technical specifications and to the design and specification of high performance production processes with low defect rates. Quality management is the general expression for all actions leading to quality. Quality management is focused on improving customer satisfaction through continuous improvement of processes including the removal of uncertain activities, and continuous improvement of the quality of processes, products and services. The quality management includes four key processes, such as quality planning, quality assurance, quality control and quality costs. The main accent in this paper will be on quality control and the application of one of the quality control tools in order to improve it. Six Sigma is different from other quality improvement concepts in that its framework is comprised of many principles, tools and techniques, which, together with experience, are all integrated and translated into best practices. Bearing in mind that the goal of every company is to work effectively and effectively in the long run, this paper focuses on Six Sigma as a way to continuously improve quality. Namely, this paper emphasizes the key features of the quality of products / services, the Need for the application of Six Sigma for quality assurance, and also a detailed list of tools and techniques that can be used during the implementation of Six Sigma.

  2. Evaluation of analytical results on DOE Quality Assessment Program Samples

    International Nuclear Information System (INIS)

    Jaquish, R.E.; Kinnison, R.R.; Mathur, S.P.; Sastry, R.

    1985-01-01

    Criteria were developed for evaluating the participants analytical results in the DOE Quality Assessment Program (QAP). Historical data from previous QAP studies were analyzed using descriptive statistical methods to determine the interlaboratory precision that had been attained. Performance criteria used in other similar programs were also reviewed. Using these data, precision values and control limits were recommended for each type of analysis performed in the QA program. Results of the analysis performed by the QAP participants on the November 1983 samples were statistically analyzed and evaluated. The Environmental Measurements Laboratory (EML) values were used as the known values and 3-sigma precision values were used as control limits. Results were submitted by 26 participating laboratories for 49 different radionuclide media combinations. The participants reported 419 results and of these, 350 or 84% were within control limits. Special attention was given to the data from gamma spectral analysis of air filters and water samples. both normal probability and box plots were prepared for each nuclide to help evaluate the distribution of the data. Results that were outside the expected range were identified and suggestions made that laboratories check calculations, and procedures on these results

  3. The dementia and disability project in Thai elderly: rational, design, methodology and early results

    Directory of Open Access Journals (Sweden)

    Senanarong Vorapun

    2013-01-01

    Full Text Available Abstract Background A strong inverse relationship of functional limitation and socioeconomic status has been established in western ageing society. Functional limitation can be related to chronic diseases, disuse, cognitive decline, and ageing. Among chronic diseases in the Thai population, cerebrovascular diseases, diabetes, and arthritis are common. These factors are known to contribute to disability and poor quality of life in the elder population. Neuropsychiatric problems, cognitive decline, dementia, and cultural issues in elderly people also can alter the quality of life of the elderly. Methods The Dementia and Disability Project in Thai Elderly (DDP aims at comprehensively assessing community dwelling Thai elderly to understand the relationship between disability and motor function, neuropsychiatric symptoms, cognitive function, and chronic diseases. The DDP is the first study to look at the prevalence and etiology of dementia and of mild cognitive impairment (MCI in Thai elders and to explore the relationship of cognition, disability, small vessel diseases and cortical degeneration with neuroimaging in Thai elderly people. 1998 Thai elders were screened in 2004–2006 and diagnosed as having MCI or dementia. 223 elders with MCI or dementia and cognitively normal elderly had brain magnetic resonance imaging (MRI or at baseline. 319 elders from the 3 groups had blood tests to investigate the risks and possible etiologies of dementia including genotyping at baseline. Results The mean age of elders in this study is 69.51(SD=6.71, min=60, max=95 years. 689(34.9% are men and 1284(65.1% are women. Mean body weight was 58.36(SD=11.20 kgs. The regression model reveals that performance on gait and balance and serum triglyceride predicts activity of daily living performance (adjusted r2 = 0.280, f=2.644, p=0.003. The majority of abnormal gait in Thai elders was lower level gait disturbance. Only 1.5% (29/1952 had highest level gait disorders. 39

  4. Preliminary results of a national quality audit programme in radiotherapy services in Cuba

    International Nuclear Information System (INIS)

    Dominguez Hung, L.; Larrinaga Cortina, E.F.; Campa Menendez, R.; Morales Lopez, J.L.; Garcia Yip, A.F.

    2001-01-01

    The current state of radiotherapy in Cuba has allowed to pass to a superior stage in the process of quality assurance, the establishment of a National Quality Audit Program (PNAC). The National Control Center for Medical Devices, as national regulator entity for the control and supervision of the medical devices of the National Health System, is responsible for the implementation of this program. This paper presents the preliminary results of the execution of the PNAC in teletherapy services with isotopic units of 60 Co. The audits were carried out according to the methodology settled down in the normalized procedure of operation of the PNAC. The physical aspects related with the treatment were audited, such as: the installation and unit's safety, mechanical and dosimetric aspects of the treatment unit and organizational aspects of the institution quality assurance program. Also carried out, in the clinical aspect, verifications of cases type planned by the qualified personnel of the service. The results corresponding to the determination of the reference dose for each institution were compared with those obtained in a postal audit with the International Atomic Energy Agency. These first audits allowed to evaluate the performance of the institutions' program of quality assurance and a feedback for the setting about to the PNAC. (author)

  5. Preliminary results of a national quality audit programme in radiotherapy services in Cuba

    Energy Technology Data Exchange (ETDEWEB)

    Dominguez Hung, L; Larrinaga Cortina, E F [Centro de Control Estatal de Equipos Medicos, Havana (Cuba); Campa Menendez, R [Centro de Proteccion e Higiene de las Radiaciones, Havana (Cuba); Morales Lopez, J L; Garcia Yip, A F [Instituto Nacional de Oncologia y Radiobiologia, Havana (Cuba)

    2001-03-01

    The current state of radiotherapy in Cuba has allowed to pass to a superior stage in the process of quality assurance, the establishment of a National Quality Audit Program (PNAC). The National Control Center for Medical Devices, as national regulator entity for the control and supervision of the medical devices of the National Health System, is responsible for the implementation of this program. This paper presents the preliminary results of the execution of the PNAC in teletherapy services with isotopic units of {sup 60}Co. The audits were carried out according to the methodology settled down in the normalized procedure of operation of the PNAC. The physical aspects related with the treatment were audited, such as: the installation and unit's safety, mechanical and dosimetric aspects of the treatment unit and organizational aspects of the institution quality assurance program. Also carried out, in the clinical aspect, verifications of cases type planned by the qualified personnel of the service. The results corresponding to the determination of the reference dose for each institution were compared with those obtained in a postal audit with the International Atomic Energy Agency. These first audits allowed to evaluate the performance of the institutions' program of quality assurance and a feedback for the setting about to the PNAC. (author)

  6. Properties of ABNT 41xx and 86xx cast steel modified with niobium; evaluation methodology and experimental preliminary results

    International Nuclear Information System (INIS)

    Suzczynski, E.F.; Chatterjee, S.; Mueller, Arno

    1982-01-01

    The experimental methodology to evaluate the mechanical properties of ABNT 41xx and 86xx steels modified with NB in the as cast and heat treated conditions and the first preliminary results obtained in a laboratory scale, are presented. (Author) [pt

  7. 2006 B100 Quality Survey Results: Milestone Report

    Energy Technology Data Exchange (ETDEWEB)

    Alleman, T. L.; McCormick, R. L.; Deutch, S.

    2007-05-01

    In 2006, the National Renewable Energy Laboratory conducted a nationwide quality survey of pure biodiesel (B100) intended to be used as a blendstock. The study collected random samples throughout the United States and analyzed them for quality against the current and proposed ASTM D6751 fuel quality specifications.

  8. Methodology assessment of the total beta activity in tobacco and tobacco products and certain results

    International Nuclear Information System (INIS)

    Georgieva, A.; Srentz, A.

    2016-01-01

    The presence of alpha and beta radionuclides in tobacco and tobacco products is a frequently discussed issue. However, any information in publications about them and their presence in tobacco products is too scarce. World Health care Organization monitors the influence of tobacco smoking on human health. In 2003, a Framework Convention on Tobacco Control was accepted with the aim to protect human health, which was signed by 179 countries, including Bulgaria. The first debates on the presence of radionuclides in tobacco products are raised in Moscow in 2014. These were instigated by data on the findings of polonium-210, reported by USA and Russia. The aim of the report is to outline a methodology to detect the presence of beta-active radionuclides in tobacco and its products. Keywords: beta activity, geiger counter, samples with infinite thickness, tobacco samples

  9. Design methodology and results evaluation of a heating functionality in modular lab-on-chip systems

    Science.gov (United States)

    Streit, Petra; Nestler, Joerg; Shaporin, Alexey; Graunitz, Jenny; Otto, Thomas

    2018-06-01

    Lab-on-a-chip (LoC) systems offer the opportunity of fast and customized biological analyses executed at the ‘point-of-need’ without expensive lab equipment. Some biological processes need a temperature treatment. Therefore, it is important to ensure a defined and stable temperature distribution in the biosensor area. An integrated heating functionality is realized with discrete resistive heating elements including temperature measurement. The focus of this contribution is a design methodology and evaluation technique of the temperature distribution in the biosensor area with regard to the thermal-electrical behaviour of the heat sources. Furthermore, a sophisticated control of the biosensor temperature is proposed. A finite element (FE) model with one and more integrated heat sources in a polymer-based LoC system is used to investigate the impact of the number and arrangement of heating elements on the temperature distribution around the heating elements and in the biosensor area. Based on this model, various LOC systems are designed and fabricated. Electrical characterization of the heat sources and independent temperature measurements with infrared technique are performed to verify the model parameters and prove the simulation approach. The FE model and the proposed methodology is the foundation for optimization and evaluation of new designs with regard to temperature requirements of the biosensor. Furthermore, a linear dependency of the heater temperature on the electric current is demonstrated in the targeted temperature range of 20 °C to 70 °C enabling the usage of the heating functionality for biological reactions requiring a steady-state temperature up to 70 °C. The correlation between heater and biosensor area temperature is derived for a direct control through the heating current.

  10. Results of the quality assurance testing program for radiopharmaceuticals 1995

    International Nuclear Information System (INIS)

    Baldas, J.; Binnyman, J.; Ivanov, Z.; Lauder, R.

    1996-07-01

    The results of the quality assurance testing conducted by the Australian Radiation Laboratory is summarised. Overall 111 batches of 27 different types of radiopharmaceuticals were tested on samples obtained through normal commercial channels. Failure to meet full specifications was observed in 10 of the 111 batches. All technetium-99m cold kits were reconstituted according to the directions in the package insert using sodium pertechnetate ( 99m Tc) injection. Radionuclidic purity has been determined at the calibration time, except for Thallous [ 201 Tl] Chloride injection where the highest impurity level up to product expiry is quoted. Non-compliance of the vial label was observed in one of the ten batches failing specification and was the sole cause of product failure for this batch. Vial label non-compliance consisted of, absence of volume in the vial. Six batches failed the biodistribution test but in no case did this involve failure of the distribution for the target organs. tabs

  11. Results of the quality assurance testing program for radiopharmaceuticals 1995

    Energy Technology Data Exchange (ETDEWEB)

    Baldas, J.; Binnyman, J.; Ivanov, Z.; Lauder, R.

    1996-07-01

    The results of the quality assurance testing conducted by the Australian Radiation Laboratory is summarised. Overall 111 batches of 27 different types of radiopharmaceuticals were tested on samples obtained through normal commercial channels. Failure to meet full specifications was observed in 10 of the 111 batches. All technetium-99m cold kits were reconstituted according to the directions in the package insert using sodium pertechnetate ( {sup 99m}Tc) injection. Radionuclidic purity has been determined at the calibration time, except for Thallous [{sup 201}Tl] Chloride injection where the highest impurity level up to product expiry is quoted. Non-compliance of the vial label was observed in one of the ten batches failing specification and was the sole cause of product failure for this batch. Vial label non-compliance consisted of, absence of volume in the vial. Six batches failed the biodistribution test but in no case did this involve failure of the distribution for the target organs. tabs.

  12. Promoting Continuous Quality Improvement in the Alabama Child Health Improvement Alliance Through Q-Sort Methodology and Learning Collaboratives.

    Science.gov (United States)

    Fifolt, Matthew; Preskitt, Julie; Rucks, Andrew; Corvey, Kathryn; Benton, Elizabeth Cason

    Q-sort methodology is an underutilized tool for differentiating among multiple priority measures. The authors describe steps to identify, delimit, and sort potential health measures and use selected priority measures to establish an overall agenda for continuous quality improvement (CQI) activities within learning collaboratives. Through an iterative process, the authors vetted a list of potential child and adolescent health measures. Multiple stakeholders, including payers, direct care providers, and organizational representatives sorted and prioritized measures, using Q-methodology. Q-methodology provided the Alabama Child Health Improvement Alliance (ACHIA) an objective and rigorous approach to system improvement. Selected priority measures were used to design learning collaboratives. An open dialogue among stakeholders about state health priorities spurred greater organizational buy-in for ACHIA and increased its credibility as a statewide provider of learning collaboratives. The integrated processes of Q-sort methodology, learning collaboratives, and CQI offer a practical yet innovative way to identify and prioritize state measures for child and adolescent health and establish a learning agenda for targeted quality improvement activities.

  13. MR imaging of the articular cartilage of the knee with arthroscopy as gold standard: assessment of methodological quality of clinical studies

    International Nuclear Information System (INIS)

    Duchateau, Florence; Berg, Bruno C. vande

    2002-01-01

    The purpose of this study was to assess the methodological quality of articles addressing the value of MR imaging of the knee cartilage with arthroscopy as a standard. Relevant papers were selected after Medline review (MEDLINE database search including the terms ''cartilage'' ''knee'', ''MR'' and ''arthroscopy''). Two observers reviewed independently 29 selected articles to determine how each study had met 15 individual standards that had been previously developed to assess the methodological quality of clinical investigations. The following criteria were met in variable percentage of articles including adequate definition of purpose (100%), statistical analysis (90%), avoidance of verification bias (86%), patient population description (83%), reference standard (79%), review bias (79%), study design (66%), inclusion criteria (41%) and method of analysis (41.5%), avoidance of diagnostic-review bias (24%), exclusion criteria (21%), indeterminate examination results (17%), analysis criteria (14%), interobserver reliability (14%) and intraobserver reliability (7%). The assessment of the methodological quality of clinical investigations addressing the value of MR imaging in the evaluation of the articular cartilage of the knee with arthroscopy as the standard of reference demonstrated that several standards were rarely met in the literature. Efforts should be made to rely on clearly defined lesion criteria and to determine reliability of the observations. (orig.)

  14. Electronic symptom reporting between patient and provider for improved health care service quality: a systematic review of randomized controlled trials. part 2: methodological quality and effects.

    Science.gov (United States)

    Johansen, Monika Alise; Berntsen, Gro K Rosvold; Schuster, Tibor; Henriksen, Eva; Horsch, Alexander

    2012-10-03

    We conducted in two parts a systematic review of randomized controlled trials (RCTs) on electronic symptom reporting between patients and providers to improve health care service quality. Part 1 reviewed the typology of patient groups, health service innovations, and research targets. Four innovation categories were identified: consultation support, monitoring with clinician support, self-management with clinician support, and therapy. To assess the methodological quality of the RCTs, and summarize effects and benefits from the methodologically best studies. We searched Medline, EMBASE, PsycINFO, Cochrane Central Register of Controlled Trials, and IEEE Xplore for original studies presented in English-language articles between 1990 and November 2011. Risk of bias and feasibility were judged according to the Cochrane recommendation, and theoretical evidence and preclinical testing were evaluated according to the Framework for Design and Evaluation of Complex Interventions to Improve Health. Three authors assessed the risk of bias and two authors extracted the effect data independently. Disagreement regarding bias assessment, extraction, and interpretation of results were resolved by consensus discussions. Of 642 records identified, we included 32 articles representing 29 studies. No articles fulfilled all quality requirements. All interventions were feasible to implement in a real-life setting, and theoretical evidence was provided for almost all studies. However, preclinical testing was reported in only a third of the articles. We judged three-quarters of the articles to have low risk for random sequence allocation and approximately half of the articles to have low risk for the following biases: allocation concealment, incomplete outcome data, and selective reporting. Slightly more than one fifth of the articles were judged as low risk for blinding of outcome assessment. Only 1 article had low risk of bias for blinding of participants and personnel. We excluded 12

  15. Feasibility study and methodology to create a quality-evaluated database of primary care data

    Directory of Open Access Journals (Sweden)

    Alison Bourke

    2004-11-01

    Conclusions In the group of practices studied, levels of recording were generally assessed to be of sufficient quality to enable a database of quality-evaluated, anonymised primary care records to be created.

  16. A methodology for elemental and organic carbon emission inventory and results for Lombardy region, Italy

    Energy Technology Data Exchange (ETDEWEB)

    Caserini, Stefano [Politecnico di Milano, DICA Environmental Engineering Section, Piazza Leonardo da Vinci 32, 20133 Milano (Italy); Galante, Silvia, E-mail: silvia1.galante@polimi.it [Politecnico di Milano, DICA Environmental Engineering Section, Piazza Leonardo da Vinci 32, 20133 Milano (Italy); Ozgen, Senem; Cucco, Sara; Gregorio, Katia de [Politecnico di Milano, DICA Environmental Engineering Section, Piazza Leonardo da Vinci 32, 20133 Milano (Italy); Moretti, Marco [Environmental Protection Agency of Lombardia Region, ARPA, 20124 Milano (Italy)

    2013-04-15

    This paper presents a methodology and its application for the compilation of elemental carbon (EC) and organic carbon (OC) emission inventories. The methodology consists of the estimation of EC and OC emissions from available total suspended particulate matter (TSP) emission inventory data using EC and OC abundances in TSP derived from an extensive literature review, by taking into account the local technological context. In particular, the method is applied to the 2008 emissions of Lombardy region, Italy, considering 148 different activities and 30 types of fuels, typical of Western Europe. The abundances estimated in this study may provide a useful basis to assess the emissions also in other emission contexts with similar prevailing sources and technologies. The dominant sources of EC and OC in Lombardy are diesel vehicles for EC and the residential wood combustion (RWC) for OC which together account for about 83% of the total emissions of both pollutants. The EC and OC emissions from industrial processes and other fuel (e.g., gasoline, kerosene and LPG) combustion are significantly lower, while non-combustion sources give an almost negligible contribution. Total EC + OC contribution to regional greenhouse gas emissions is positive for every sector assuming whichever GWP100 value within the range proposed in literature. An uncertainty assessment is performed through a Monte Carlo simulation for RWC, showing a large uncertainty range (280% of the mean value for EC and 70% for OC), whereas for road transport a qualitative analysis identified a narrower range of uncertainty. - Highlights: ► Diesel and wood combustion contribute to more than 80% of total EC and OC. ► More than 50% of EC emissions come from road transport. ► Monte Carlo method is used to assess the uncertainty of wood combustion emissions. ► Residential wood combustion is the main source of uncertainty of EC OC inventory. ► In terms of CO{sub 2}eq, EC and OC correspond to 3% of CO{sub 2

  17. Research into Learning Resulting from Quality School Library Media Service.

    Science.gov (United States)

    Marchant, Maurice P.; And Others

    1984-01-01

    This annotated bibliography of 20 research reports identifies what has been determined about the effects of library media services on learning and suggests methodologies available for similar studies. Organization is according to area of learning affected--academic achievement; language, reading, and library skills; mathematics; science; social…

  18. On the quality of global emission inventories. Approaches, methodologies, input data and uncertainties

    International Nuclear Information System (INIS)

    Olivier, J.G.J.

    2002-01-01

    Four key scientific questions will be investigated: (1) How does a user define the 'quality' of a global (or national) emission inventory? (Chapter 2); (2) What determines the quality of a global emission inventory? (Chapters 2 and 7); (3) How can inventory quality be achieved in practice and expressed in quantitative terms ('uncertainty')? (Chapters 3 to 6); and (4) What is the preferred approach for compiling a global emission inventory, given the practical limitations and the desired inventory quality? (Chapters 7 and 8)

  19. Verification of dosimetric methodology for auditing radiotherapy quality under non-reference condition in Hubei province

    International Nuclear Information System (INIS)

    Ma Xinxing; Luo Suming; He Zhijian; Zhou Wenshan

    2014-01-01

    Objective: To verify the reliability of TLD-based quality audit for radiotherapy dosimetry of medical electron accelerator in non-reference condition by monitoring the dose variations from electron beams with different field sizes and 45° wedge and the dose variations from photon beams with different field sizes and source-skin distance. Methods: Both TLDs and finger ionization chambers were placed at a depth of 10 cm in water to measure the absorbed dose from photon beams, and also placed at the depth of maximum dose from electron beams under non-reference condition. TLDs were then mailed to National Institute for Radiological Protection, China CDC for further measurement. Results: Among the 70 measuring points for photon beams, 58 points showed the results with a relative error less than ±7.0% (IAEA's acceptable deviation: ±7.0%) between TLDs and finger ionization chambers measurements, and the percentage of qualified point numbers was 82.8%. After corrected by Ps value, 62 points were qualified and the percentage was up to 88.6%. All of the measuring points for electron beams, with the total number of 24, presented a relative error within ±5.0% (IAEA's acceptable deviation: ±5.0%) between TLDs and finger ioization cylindrical chambers measurements. Conclusions: TLD-based quality audit is convenient for determining radiotherapy dosimetric parameters of electron beams in non-reference condition and can improve the accuracy of the measuring parameters in connection with finger chambers. For electron beams of 5 MeV < E_0 < 10 MeV, the absorbed dose parameters measured by finger ionization chambers, combined with TLD audit, can help obtain the precise and reliable results. (authors)

  20. A staffing decision support methodology using a quality loss function : a cross-disciplinary quantitative study

    NARCIS (Netherlands)

    Mincsovics, G.Z.

    2009-01-01

    Background Understanding the quality loss implications of short staffing is essential in maintaining service quality on a limited budget. Objectives For elaborate financial control on staffing decisions, it is necessary to quantify the cost of the incidental quality loss that a given workload and

  1. Some problems in methodology of economjc evaluation of radiation technique quality

    International Nuclear Information System (INIS)

    Kodyukov, V.M.; Purtova, M.I.; Sokolova, Z.I.; Smirnova, Z.M.

    1976-01-01

    The quality of radiation equipment (RE) should essentially be assessed when designing, standardizing, planning, and evaluating the cost and economy of RE. The basic factors are sited upon which subsequent economic assessment of quality levels were based. It also discusses the specifics involved in determining the principal quality factors for radioisotopic flaw-detection equipment and gamma-therapeutic instruments

  2. Quality Adjusted Life Years and Trade Off Exercises : exploring methodology and validity

    NARCIS (Netherlands)

    Verschuuren, Marieke

    2006-01-01

    Quality Adjusted Life Years (QALYs) are a popular outcome measure in cost-effectiveness analyses. QALYs are computed by multiplying follow-up or survival by a scaling factor reflecting health related quality of life, and as such capture quantity and quality gains simultaneously. Issues with regard

  3. A semi-quantitative reasoning methodology for filtering and ranking HAZOP results in HAZOPExpert

    International Nuclear Information System (INIS)

    Vaidhyanathan, Ramesh; Venkatasubramanian, Venkat

    1996-01-01

    Hazard and Operability (HAZOP) analysis is the most widely used and recognized as the preferred Process Hazards Analysis (PHA) approach in the chemical process industry. Recently, a diagraph-model based framework and an expert system called HAZOPExpert was developed for automating this analysis. Upon testing the performance of the system on various industrial case studies. HAZOPExpert was found to successfully mimic the human expert's reasoning and identify the hazards. But, with the increasing complexity of the processes, the HAZOPExpert system generated a large number of consequences compared to those identified by a team of experts. This is mainly due to the strict qualitative reasoning approach implemented in the HAZOPExpert system. In order to filter and rank the consequences generated by the HAZOPExpert system, a semi-quantitative reasoning methodology is proposed using additional quantitative knowledge in the form of design and operating specifications of the process units, and process material property values. This filtering approach combines the qualitative digraph-based HAZOP models and the quantitative knowledge to eliminate the unrealizable consequences. Significant reduction in the number of consequences was obtained using this approach on an ethylene process plant HAZOP case study

  4. U.S. Natural Gas Storage Risk-Based Ranking Methodology and Results

    Energy Technology Data Exchange (ETDEWEB)

    Folga, Steve [Argonne National Lab. (ANL), Argonne, IL (United States); Portante, Edgar [Argonne National Lab. (ANL), Argonne, IL (United States); Shamsuddin, Shabbir [Argonne National Lab. (ANL), Argonne, IL (United States); Tompkins, Angeli [Argonne National Lab. (ANL), Argonne, IL (United States); Talaber, Leah [Argonne National Lab. (ANL), Argonne, IL (United States); McLamore, Mike [Argonne National Lab. (ANL), Argonne, IL (United States); Kavicky, Jim [Argonne National Lab. (ANL), Argonne, IL (United States); Conzelmann, Guenter [Argonne National Lab. (ANL), Argonne, IL (United States); Levin, Todd [Argonne National Lab. (ANL), Argonne, IL (United States)

    2016-10-01

    This report summarizes the methodology and models developed to assess the risk to energy delivery from the potential loss of underground gas storage (UGS) facilities located within the United States. The U.S. has a total of 418 existing storage fields, of which 390 are currently active. The models estimate the impacts of a disruption of each of the active UGS facilities on their owners/operators, including (1) local distribution companies (LDCs), (2) directly connected transporting pipelines and thus on the customers in downstream States, and (3) third-party entities and thus on contracted customers expecting the gas shipment. Impacts are measured across all natural gas customer classes. For the electric sector, impacts are quantified in terms of natural gas-fired electric generation capacity potentially affected from the loss of a UGS facility. For the purpose of calculating the overall supply risk, the overall consequence of the disruption of an UGS facility across all customer classes is expressed in terms of the number of expected equivalent residential customer outages per year, which combines the unit business interruption cost per customer class and the estimated number of affected natural gas customers with estimated probabilities of UGS disruptions. All models and analyses are based on publicly available data. The report presents a set of findings and recommendations in terms of data, further analyses, regulatory requirements and standards, and needs to improve gas/electric industry coordination for electric reliability.

  5. Roselle (Hibiscus sabdariffa L.) and soybean oil effects on quality characteristics of pork patties studied by response surface methodology.

    Science.gov (United States)

    Jung, Eunkyung; Joo, Nami

    2013-07-01

    Response surface methodology was used to investigate the effect and interactions of processing variables such as roselle extract (0.1-1.3%), soybean oil (5-20%) on physicochemical, textural and sensory properties of cooked pork patties. It was found that reduction in thickness, pH, L* and b* values decreased; however, water-holding capacity, reduction in diameter and a* values increased, respectively, as the amount of roselle increased. Soybean oil addition increased water-holding capacity, reduction in thickness, b* values of the patties. The hardness depended on the roselle and soybean oil added, as its linear effect was negative at proselle and soybean oil. The maximum overall quality score (5.42) was observed when 12.5 g of soybean oil and 0.7 g of roselle extract was added. The results of this optimization study would be useful for meat industry that tends to increase the product yield for patties using the optimum levels of ingredients by RSM. Copyright © 2013 Elsevier Ltd. All rights reserved.

  6. Randomized clinical trials in dentistry: Risks of bias, risks of random errors, reporting quality, and methodologic quality over the years 1955-2013.

    Directory of Open Access Journals (Sweden)

    Humam Saltaji

    Full Text Available To examine the risks of bias, risks of random errors, reporting quality, and methodological quality of randomized clinical trials of oral health interventions and the development of these aspects over time.We included 540 randomized clinical trials from 64 selected systematic reviews. We extracted, in duplicate, details from each of the selected randomized clinical trials with respect to publication and trial characteristics, reporting and methodologic characteristics, and Cochrane risk of bias domains. We analyzed data using logistic regression and Chi-square statistics.Sequence generation was assessed to be inadequate (at unclear or high risk of bias in 68% (n = 367 of the trials, while allocation concealment was inadequate in the majority of trials (n = 464; 85.9%. Blinding of participants and blinding of the outcome assessment were judged to be inadequate in 28.5% (n = 154 and 40.5% (n = 219 of the trials, respectively. A sample size calculation before the initiation of the study was not performed/reported in 79.1% (n = 427 of the trials, while the sample size was assessed as adequate in only 17.6% (n = 95 of the trials. Two thirds of the trials were not described as double blinded (n = 358; 66.3%, while the method of blinding was appropriate in 53% (n = 286 of the trials. We identified a significant decrease over time (1955-2013 in the proportion of trials assessed as having inadequately addressed methodological quality items (P < 0.05 in 30 out of the 40 quality criteria, or as being inadequate (at high or unclear risk of bias in five domains of the Cochrane risk of bias tool: sequence generation, allocation concealment, incomplete outcome data, other sources of bias, and overall risk of bias.The risks of bias, risks of random errors, reporting quality, and methodological quality of randomized clinical trials of oral health interventions have improved over time; however, further efforts that contribute to the development of more stringent

  7. Rating the methodological quality of single-subject designs and n-of-1 trials: introducing the Single-Case Experimental Design (SCED) Scale.

    Science.gov (United States)

    Tate, Robyn L; McDonald, Skye; Perdices, Michael; Togher, Leanne; Schultz, Regina; Savage, Sharon

    2008-08-01

    Rating scales that assess methodological quality of clinical trials provide a means to critically appraise the literature. Scales are currently available to rate randomised and non-randomised controlled trials, but there are none that assess single-subject designs. The Single-Case Experimental Design (SCED) Scale was developed for this purpose and evaluated for reliability. Six clinical researchers who were trained and experienced in rating methodological quality of clinical trials developed the scale and participated in reliability studies. The SCED Scale is an 11-item rating scale for single-subject designs, of which 10 items are used to assess methodological quality and use of statistical analysis. The scale was developed and refined over a 3-year period. Content validity was addressed by identifying items to reduce the main sources of bias in single-case methodology as stipulated by authorities in the field, which were empirically tested against 85 published reports. Inter-rater reliability was assessed using a random sample of 20/312 single-subject reports archived in the Psychological Database of Brain Impairment Treatment Efficacy (PsycBITE). Inter-rater reliability for the total score was excellent, both for individual raters (overall ICC = 0.84; 95% confidence interval 0.73-0.92) and for consensus ratings between pairs of raters (overall ICC = 0.88; 95% confidence interval 0.78-0.95). Item reliability was fair to excellent for consensus ratings between pairs of raters (range k = 0.48 to 1.00). The results were replicated with two independent novice raters who were trained in the use of the scale (ICC = 0.88, 95% confidence interval 0.73-0.95). The SCED Scale thus provides a brief and valid evaluation of methodological quality of single-subject designs, with the total score demonstrating excellent inter-rater reliability using both individual and consensus ratings. Items from the scale can also be used as a checklist in the design, reporting and critical

  8. Nationwide quality improvement of cholecystectomy: results from a national database

    DEFF Research Database (Denmark)

    Harboe, Kirstine M; Bardram, Linda

    2011-01-01

    To evaluate whether quality improvements in the performance of cholecystectomy have been achieved in Denmark since 2006, after revision of the Danish National Guidelines for treatment of gallstones.......To evaluate whether quality improvements in the performance of cholecystectomy have been achieved in Denmark since 2006, after revision of the Danish National Guidelines for treatment of gallstones....

  9. Dark Energy Survey Year 1 Results: Multi-Probe Methodology and Simulated Likelihood Analyses

    Energy Technology Data Exchange (ETDEWEB)

    Krause, E.; et al.

    2017-06-28

    We present the methodology for and detail the implementation of the Dark Energy Survey (DES) 3x2pt DES Year 1 (Y1) analysis, which combines configuration-space two-point statistics from three different cosmological probes: cosmic shear, galaxy-galaxy lensing, and galaxy clustering, using data from the first year of DES observations. We have developed two independent modeling pipelines and describe the code validation process. We derive expressions for analytical real-space multi-probe covariances, and describe their validation with numerical simulations. We stress-test the inference pipelines in simulated likelihood analyses that vary 6-7 cosmology parameters plus 20 nuisance parameters and precisely resemble the analysis to be presented in the DES 3x2pt analysis paper, using a variety of simulated input data vectors with varying assumptions. We find that any disagreement between pipelines leads to changes in assigned likelihood $\\Delta \\chi^2 \\le 0.045$ with respect to the statistical error of the DES Y1 data vector. We also find that angular binning and survey mask do not impact our analytic covariance at a significant level. We determine lower bounds on scales used for analysis of galaxy clustering (8 Mpc$~h^{-1}$) and galaxy-galaxy lensing (12 Mpc$~h^{-1}$) such that the impact of modeling uncertainties in the non-linear regime is well below statistical errors, and show that our analysis choices are robust against a variety of systematics. These tests demonstrate that we have a robust analysis pipeline that yields unbiased cosmological parameter inferences for the flagship 3x2pt DES Y1 analysis. We emphasize that the level of independent code development and subsequent code comparison as demonstrated in this paper is necessary to produce credible constraints from increasingly complex multi-probe analyses of current data.

  10. The Effects of Quality Management Practices on Key Results: questionnaires sample for the industry of tourist accommodation in Spain

    Directory of Open Access Journals (Sweden)

    José Álvarez García

    2014-12-01

    Full Text Available In this research work, we examine the direct and indirect effects of quality management practices on key results and we identify the relationship between quality practices. To achieve the proposed objective, a structural model was used, taking into account the previous review of the literature, in order to identify the quality practices and causal relationships with the key results. The theoretical model and hypotheses are tested using data collected from a sample of 186 tourist accommodation companies certified with the “Q for Tourist Quality” standard in Spain, from a questionnaire based on quality practices identified in the literature and on the EFQM Model, taking some of the most relevant scales as a reference. The methodology used consists of the application of an Exploratory and Confirmatory Factorial Analysis to validate the scales (reliability, one-dimensionality and validity and define the number of items of each of the measuring instruments of the constructs proposed, to then estimate the causal model proposed, proceeding to test the hypotheses formulated by using the Structural Equation Model (SEM technique. The results achieved support the relationship between quality practices and the direct and positive impact of two of the practices, processes management and quality policy/planning, on the key results. It was also observed that the quality practices that most influence key results are quality policy/planning along with leadership, when considering the total effects (direct and indirect.

  11. Mobile and Web 2.0 interventions for weight management: an overview of review evidence and its methodological quality.

    Science.gov (United States)

    Bardus, Marco; Smith, Jane R; Samaha, Laya; Abraham, Charles

    2016-08-01

    The use of Internet and related technologies for promoting weight management (WM), physical activity (PA), or dietary-related behaviours has been examined in many articles and systematic reviews. This overview aims to summarize and assess the quality of the review evidence specifically focusing on mobile and Web 2.0 technologies, which are the most utilized, currently available technologies. Following a registered protocol (CRD42014010323), we searched 16 databases for articles published in English until 31 December 2014 discussing the use of either mobile or Web 2.0 technologies to promote WM or related behaviors, i.e. diet and physical activity (PA). Two reviewers independently selected reviews and assessed their methodological quality using the AMSTAR checklist. Citation matrices were used to determine the overlap among reviews. Forty-four eligible reviews were identified, 39 of which evaluated the effects of interventions using mobile or Web 2.0 technologies. Methodological quality was generally low with only 7 reviews (16%) meeting the highest standards. Suggestive evidence exists for positive effects of mobile technologies on weight-related outcomes and, to a lesser extent, PA. Evidence is inconclusive regarding Web 2.0 technologies. Reviews on mobile and Web 2.0 interventions for WM and related behaviors suggest that these technologies can, under certain circumstances, be effective, but conclusions are limited by poor review quality based on a heterogeneous evidence base. © The Author 2016. Published by Oxford University Press on behalf of the European Public Health Association. All rights reserved.

  12. Applying the Tropos Methodology for Analysing Web Services Requirements and Reasoning about Qualities of Services

    NARCIS (Netherlands)

    Aiello, Marco; Giorgini, Paolo

    2004-01-01

    The shift in software engineering from the design, implementation and management of isolated software elements towards a network of autonomous interoperable service is calling for a shift in the way software is designed. We propose the use of the agent-oriented methodology Tropos for the analysis of

  13. A Comparison of the Methodological Quality of Articles in Computer Science Education Journals and Conference Proceedings

    Science.gov (United States)

    Randolph, Justus J.; Julnes, George; Bednarik, Roman; Sutinen, Erkki

    2007-01-01

    In this study we empirically investigate the claim that articles published in computer science education journals are more methodologically sound than articles published in computer science education conference proceedings. A random sample of 352 articles was selected from those articles published in major computer science education forums between…

  14. The Rock Engineering System (RES) applied to landslide susceptibility zonation of the northeastern flank of Etna: methodological approach and results

    Science.gov (United States)

    Apuani, Tiziana; Corazzato, Claudia

    2015-04-01

    Ground deformations in the northeastern flank of Etna are well known. Despite only a few landslide events have been documented, these have significantly involved and damaged lifelines and buildings. These events are mainly related to the activity of the volcano-tectonic structures and associated seismicity, as in the case of the 2002 reactivation of the Presa landslide during an increased activity of the Pernicana fault system. In order to highlight the areal distribution of potentially unstable slopes based on a detailed, site-specific study of the factors responsible for landslide, and to ultimately contribute to risk management, a landslide susceptibility analysis of the northeastern flank of Etna in the Pernicana area was carried out, and a susceptibility map at 1:10.000 scale was produced, extending over an area of 168 km2. Different methods are proposed in the literature to obtain the regional distribution of potentially unstable slopes, depending on the problem scale, the slope dynamic evolution in the geological context, and the availability of data. Among semi-quantitative approaches, the present research combines the Rock Engineering System (RES) methodology with parameter zonation mapping in a GIS environment. The RES method represents a structured approach to manage a high number of interacting factors involved in the instability problem. A numerically coded, site-specific interaction matrix (IM) analyzes the cause-effect relationship in these factors, and calculates the degree of interactivity of each parameter, normalized by the overall interactivity of the system (weight factor). In the specific Etna case, the considered parameters are: slope attitude, lithotechnical properties (lithology, structural complexity, soil and rock mass quality), land use, tectonic structures, seismic activity (horizontal acceleration) and hydrogeological conditions (groundwater and drainage). Thematic maps are prepared at 1:10.000 scale for each of these parameters, and

  15. [Methodological quality of articles on therapeutic procedures published in Cirugía Española. Evaluation of the period 2005-2008].

    Science.gov (United States)

    Manterola, Carlos; Grande, Luís

    2010-04-01

    To determine methodological quality of therapy articles published in Cirugía Española and to study its association with the publication year, the centre of origin and subjects. A literature study which included all therapy articles published between 2005 and 2008. All kinds of clinical designs were considered, excluding editorials, review articles, letters to editor and experimental studies. Variables analysed included: year of publication, centre of origin, design, and methodological quality of articles. A valid and reliable scale was applied to determine methodological quality. A total of 243 articles [206 series of cases (84.8%), 27 cohort studies (11.1%), 9 clinical trials (3.7%) and 1 case control study (0.4%)] were found. Studies came preferentially from Catalonia and Valencia (22.3% and 12.3% respectively). Thematic areas most frequently found were hepato-bilio-pancreatic and colorectal surgery (20.0% and 16.6%, respectively). Average and median of the methodological quality score calculated for the entire series were 9.5+/-4.3 points and 8 points, respectively. Association between methodological quality and geographical area (p=0.0101), subject area (p=0.0267), and university origin (p=0.0369) was found. A significant increase of methodological quality by publication year was observed (p=0.0004). Methodological quality of therapy articles published in Cirugía Española between 2005 and 2008 is low; but an increase tendency with statistical significance was observed.

  16. Can formal collaborative methodologies improve quality in primary health care in New Zealand? Insights from the EQUIPPED Auckland Collaborative.

    Science.gov (United States)

    Palmer, Celia; Bycroft, Janine; Healey, Kate; Field, Adrian; Ghafel, Mazin

    2012-12-01

    Auckland District Health Board was one of four District Health Boards to trial the Breakthrough Series (BTS) methodology to improve the management of long-term conditions in New Zealand, with support from the Ministry of Health. To improve clinical outcomes, facilitate planned care and promote quality improvement within participating practices in Auckland. Implementation of the Collaborative followed the improvement model / Institute for Healthcare Improvement methodology. Three topic areas were selected: system redesign, cardio-vascular disease/diabetes, and self-management support. An expert advisory group and the Improvement Foundation Australia helped guide project development and implementation. Primary Health Organisation facilitators were trained in the methodology and 15 practice teams participated in the three learning workshops and action periods over 12 months. An independent evaluation study using both quantitative and qualitative methods was conducted. Improvements were recorded in cardiovascular disease risk assessment, practice-level systems of care, self-management systems and follow-up and coordination for patients. Qualitative research found improvements in coordination and teamwork, knowledge of practice populations and understanding of managing long-term conditions. The Collaborative process delivered some real improvements in the systems of care for people with long-term conditions and a change in culture among participating practices. The findings suggest that by strengthening facilitation processes, improving access to comprehensive population audit tools and lengthening the time frame, the process has the potential to make significant improvements in practice. Other organisations should consider this approach when investigating quality improvement programmes.

  17. Results-driven approach to improving quality and productivity

    Science.gov (United States)

    John Dramm

    2000-01-01

    Quality control (QC) programs do not often realize their full potential. Elaborate and expensive QC programs can easily get side tracked by the process of building a program with promises of “Someday, this will all pay off.” Training employees in QC methods is no guarantee that quality will improve. Several documented cases show that such activity-centered efforts...

  18. Uncertainty in Odyssee indicators and energy savings. Development of a methodology and first results

    Energy Technology Data Exchange (ETDEWEB)

    Boonekamp, P.G.M.; Gerdes, J. [ECN Policy Studies, Petten (Netherlands); Faberi, S. [Institute of Studies for the Integration of Systems ISIS, Rome (Italy)

    2013-12-15

    The ODYSSEE database on energy efficiency indicators (www.odyssee-indicators.org) has been set up to enable the monitoring and evaluation of realised energy efficiency improvements and related energy savings. The database covers the 27 EU countries as well as Norway and Croatia. Energy indicators that relate energy consumption to a physical output (ton of steel), a performance (person-km driven per car) or the number of energy using devices (refrigerators) can show the increase in energy efficiency realised, and the amount of energy saved. By aggregating indicators, Odyssee calculates energy efficiency indices by sector and for the whole economy (so-called ODEX), in order to evaluate overall energy efficiency progress. This work contributes to the growing need for quantitative monitoring and evaluation of the impacts of energy policies and measures, both at the EU and national level, e.g. due to the Energy Service Directive. Because of the central role of Odyssee indicators in policy evaluations it becomes more important to know how reliable the Odyssee figures are, or in other words, what is the uncertainty margin for the indicator values and the related savings. This report presents a first analysis of uncertainty margins in the indicators and savings figures. The work builds on earlier work in the preceding Odyssee project with regard to the quality of input data used in Odyssee.

  19. Lean practices for quality results: a case illustration.

    Science.gov (United States)

    Hwang, Pauline; Hwang, David; Hong, Paul

    2014-01-01

    Increasingly, healthcare providers are implementing lean practices to achieve quality results. Implementing lean healthcare practices is unique compared to manufacturing and other service industries. The purpose of this paper is to present a model that identifies and defines the lean implementation key success factors in healthcare organisations. The model is based on an extant literature review and a case illustration that explores actual lean implementation in a major USA hospital located in a Midwestern city (approximately 300,000 people). An exploratory/descriptive study using observation and follow-up interviews was conducted to identify lean practices in the hospital. Lean practice key drivers include growing elderly populations, rising medical expenses, decreasing insurance coverage and decreasing management support. Effectively implementing lean practices to increase bottom-line results and improve organisational integrity requires sharing goals and processes among healthcare managers and professionals. An illustration explains the model and the study provides a sound foundation for empirical work. Practical implications are included. Lean practices minimise waste and unnecessary hospital stays while simultaneously enhancing customer values and deploying resources in supply systems. Leadership requires clear project targets based on sound front-end planning because initial implementation steps involve uncertainty and ambiguity (i.e. fuzzy front-end planning). Since top management support is crucial for implementing lean practices successfully, a heavyweight manager, who communicates well both with top managers and project team members, is an important success factor when implementing lean practices. Increasingly, green orientation and sustainability initiatives are phrases that replaced lean practices. Effective results; e.g. waste reduction, employee satisfaction and customer values are applicable to bigger competitive challenges arising both in specific

  20. Quality of research results in agro-economy by data mining

    Directory of Open Access Journals (Sweden)

    Vukelić Gordana

    2015-01-01

    Full Text Available Data Mining (DM through data in agroeconomy is a scientific method that enables researchers not to go through set research scenarioes that are predetermined assumptions and hypotheses on the basis of insignificant atributes. On the contrary, by data mining detection of these atributes is made possible, in general, those hiden facts that enable setting a hypothesis. The DM method does this by an iterative way, including key atributes and factors and their influence on the quality of agro-resources. The research was conducted on a random sample, by analyzing the quality of eggs. The research subject is the posibility of classifying and predicting significant variablesatributes that determine the level of egg quality. The research starts from the use of Data Mining, as an area of machine studies, which significantly helps researchers in optimizing research. The applied methodology during research includes analyticalsintetic procedures and methods of Data Mining, with a special focus on using Supervised linear discrimination analysis and the Decision Tree. The results indicate significant posibilities of using DM as an additional analytical procedure in performing agroresearch and it can be concluded that it contributes to an improvement in effectiveness and validity of process in performing these researches.

  1. The Dementia and Disability Project in Thai Elderly: rational, design, methodology and early results.

    Science.gov (United States)

    Senanarong, Vorapun; Harnphadungkit, Kamolthip; Poungvarin, Niphon; Vannasaeng, Sathit; Chongwisal, Samut; Chakorn, Tipa; Jamjumrus, Piyanuch; Raksthaput, Atthapon; Chaichanettee, Sinisa; Aoonkaew, Nattapol; Udompunthurak, Suthipol; Doody, Rachelle S; Cummings, Jeffrey L

    2013-01-10

    A strong inverse relationship of functional limitation and socioeconomic status has been established in western ageing society. Functional limitation can be related to chronic diseases, disuse, cognitive decline, and ageing. Among chronic diseases in the Thai population, cerebrovascular diseases, diabetes, and arthritis are common. These factors are known to contribute to disability and poor quality of life in the elder population. Neuropsychiatric problems, cognitive decline, dementia, and cultural issues in elderly people also can alter the quality of life of the elderly. The Dementia and Disability Project in Thai Elderly (DDP) aims at comprehensively assessing community dwelling Thai elderly to understand the relationship between disability and motor function, neuropsychiatric symptoms, cognitive function, and chronic diseases. The DDP is the first study to look at the prevalence and etiology of dementia and of mild cognitive impairment (MCI) in Thai elders and to explore the relationship of cognition, disability, small vessel diseases and cortical degeneration with neuroimaging in Thai elderly people. 1998 Thai elders were screened in 2004-2006 and diagnosed as having MCI or dementia. 223 elders with MCI or dementia and cognitively normal elderly had brain magnetic resonance imaging (MRI) or at baseline. 319 elders from the 3 groups had blood tests to investigate the risks and possible etiologies of dementia including genotyping at baseline. The mean age of elders in this study is 69.51(SD=6.71, min=60, max=95) years. 689(34.9%) are men and 1284(65.1%) are women. Mean body weight was 58.36(SD=11.20) kgs. The regression model reveals that performance on gait and balance and serum triglyceride predicts activity of daily living performance (adjusted r2 = 0.280, f=2.644, p=0.003). The majority of abnormal gait in Thai elders was lower level gait disturbance. Only 1.5% (29/1952) had highest level gait disorders. 39.5% of 1964 subjects were free of chronic diseases

  2. Quality Assurance Results for a Commercial Radiosurgery System: A Communication.

    Science.gov (United States)

    Ruschin, Mark; Lightstone, Alexander; Beachey, David; Wronski, Matt; Babic, Steven; Yeboah, Collins; Lee, Young; Soliman, Hany; Sahgal, Arjun

    2015-10-01

    The purpose of this communication is to inform the radiosurgery community of quality assurance (QA) results requiring attention in a commercial FDA-approved linac-based cone stereo-tactic radiosurgery (SRS) system. Standard published QA guidelines as per the American Association of Physics in Medicine (AAPM) were followed during the SRS system's commissioning process including end-to-end testing, cone concentricity testing, image transfer verification, and documentation. Several software and hardware deficiencies that were deemed risky were uncovered during the process and QA processes were put in place to mitigate these risks during clinical practice. In particular, the present work focuses on daily cone concentricity testing and commissioning-related findings associated with the software. Cone concentricity/alignment is measured daily using both optical light field inspection, as well as quantitative radiation field tests with the electronic portal imager. In 10 out of 36 clini-cal treatments, adjustments to the cone position had to be made to align the cone with the collimator axis to less than 0.5 mm and on two occasions the pre-adjustment measured offset was 1.0 mm. Software-related errors discovered during commissioning included incorrect transfer of the isocentre in DICOM coordinates, improper handling of non-axial image sets, and complex handling of beam data, especially for multi-target treatments. QA processes were established to mitigate the occurrence of the software errors. With proper QA processes, the reported SRS system complies with tolerances set out in established guidelines. Discussions with the vendor are ongoing to address some of the hardware issues related to cone alignment. © The Author(s) 2014.

  3. Proteomics Quality Control: Quality Control Software for MaxQuant Results.

    Science.gov (United States)

    Bielow, Chris; Mastrobuoni, Guido; Kempa, Stefan

    2016-03-04

    Mass spectrometry-based proteomics coupled to liquid chromatography has matured into an automatized, high-throughput technology, producing data on the scale of multiple gigabytes per instrument per day. Consequently, an automated quality control (QC) and quality analysis (QA) capable of detecting measurement bias, verifying consistency, and avoiding propagation of error is paramount for instrument operators and scientists in charge of downstream analysis. We have developed an R-based QC pipeline called Proteomics Quality Control (PTXQC) for bottom-up LC-MS data generated by the MaxQuant software pipeline. PTXQC creates a QC report containing a comprehensive and powerful set of QC metrics, augmented with automated scoring functions. The automated scores are collated to create an overview heatmap at the beginning of the report, giving valuable guidance also to nonspecialists. Our software supports a wide range of experimental designs, including stable isotope labeling by amino acids in cell culture (SILAC), tandem mass tags (TMT), and label-free data. Furthermore, we introduce new metrics to score MaxQuant's Match-between-runs (MBR) functionality by which peptide identifications can be transferred across Raw files based on accurate retention time and m/z. Last but not least, PTXQC is easy to install and use and represents the first QC software capable of processing MaxQuant result tables. PTXQC is freely available at https://github.com/cbielow/PTXQC .

  4. Evaluation of the environmental epidemiologic data and methodology for the air quality standard in Beijing

    Science.gov (United States)

    Li, Xu; Jiang, Yanfeng; Yin, Ling; Liu, Bo; Du, Pengfei; Hassan, Mujtaba; Wang, Shigong; Li, Tanshi

    2017-09-01

    To evaluate the relationship between exposure to air pollutants and respiratory emergency room visits, a generalized additive model (GAM) was used to analyze the exposure-effect relationship between air pollutants and respiratory emergency room visits. The results showed that NO2, SO2, and PM10 have positive relationships with respiratory disease. Concentration increases of 10 μg/m3 in NO2, SO2, and PM10 corresponded to 3.90% (95%CI 3.56-4.25), 0.81% (95%CI -0.09-1.72), and 0.64% (95%CI 0.55-0.74) increases in respiratory emergency room visits. In addition, there is a strong synergic effect of PM10 and NO2 on respiratory diseases. The threshold values of the national standard grade II limits used in Beijing should be adjusted. An appropriate standard could effectively promote a significant decline in respiratory room visits and would eventually be beneficial to air quality management in residential areas.

  5. A Proposed Methodology to Assess the Quality of Public Use Management in Protected Areas

    Science.gov (United States)

    Muñoz-Santos, Maria; Benayas, Javier

    2012-07-01

    In recent years, the goal of nature preservation has faced, almost worldwide, an increase in the number of visitors who are interested in experiencing protected areas resources, landscapes and stories. Spain is a good example of this process. The rapidly increasing numbers of visitors have prompted administrations and managers to offer and develop a broad network of facilities and programs in order to provide these visitors with information, knowledge and recreation. But, are we doing it the best way? This research focuses on developing and applying a new instrument for evaluating the quality of visitor management in parks. Different areas are analyzed with this instrument (78 semi-quantitative indicators): planning and management capacity (planning, funding, human resources), monitoring, reception, information, interpretation, environmental education, training, participation and volunteer's programs. Thus, we attempt to gain a general impression of the development of the existing management model, detecting strengths and weaknesses. Although Spain's National Parks constituted the specific context within which to develop the evaluation instrument, the design thereof is intended to provide a valid, robust and flexible method for application to any system, network or set of protected areas in other countries. This paper presents the instrument developed, some results obtained following its application to Spanish National parks, along with a discussion on the limits and validity thereof.

  6. Methodology for Evaluating the Quality of Ecosystem Maps: A Case Study in the Andes

    Directory of Open Access Journals (Sweden)

    Dolors Armenteras

    2016-08-01

    Full Text Available Uncertainty in thematic maps has been tested mainly in maps with discrete or fuzzy classifications based on spectral data. However, many ecosystem maps in tropical countries consist of discrete polygons containing information on various ecosystem properties such as vegetation cover, soil, climate, geomorphology and biodiversity. The combination of these properties into one class leads to error. We propose a probability-based sampling design with two domains, multiple stages, and stratification with selection of primary sampling units (PSUs proportional to the richness of strata present. Validation is undertaken through field visits and fine resolution remote sensing data. A pilot site in the center of the Colombian Andes was chosen to validate a government official ecosystem map. Twenty primary sampling units (PSUs of 10 × 15 km were selected, and the final numbers of final sampling units (FSUs were 76 for the terrestrial domain and 46 for the aquatic domain. Our results showed a confidence level of 95%, with the accuracy in the terrestrial domain varying between 51.8% and 64.3% and in the aquatic domain varying between 75% and 92%. Governments need to account for uncertainty since they rely on the quality of these maps to make decisions and guide policies.

  7. Are methodological quality and completeness of reporting associated with citation-based measures of publication impact? A secondary analysis of a systematic review of dementia biomarker studies.

    Science.gov (United States)

    Mackinnon, Shona; Drozdowska, Bogna A; Hamilton, Michael; Noel-Storr, Anna H; McShane, Rupert; Quinn, Terry

    2018-03-22

    To determine whether methodological and reporting quality are associated with surrogate measures of publication impact in the field of dementia biomarker studies. We assessed dementia biomarker studies included in a previous systematic review in terms of methodological and reporting quality using the Quality Assessment of Diagnostic Accuracy Studies (QUADAS) and Standards for Reporting of Diagnostic Accuracy (STARD), respectively. We extracted additional study and journal-related data from each publication to account for factors shown to be associated with impact in previous research. We explored associations between potential determinants and measures of publication impact in univariable and stepwise multivariable linear regression analyses. We aimed to collect data on four measures of publication impact: two traditional measures-average number of citations per year and 5-year impact factor of the publishing journal and two alternative measures-the Altmetric Attention Score and counts of electronic downloads. The systematic review included 142 studies. Due to limited data, Altmetric Attention Scores and electronic downloads were excluded from the analysis, leaving traditional metrics as the only analysed outcome measures. We found no relationship between QUADAS and traditional metrics. Citation rates were independently associated with 5-year journal impact factor (β=0.42; pcitation rates (β=0.45; pCitation rates and 5-year journal impact factor appear to measure different dimensions of impact. Citation rates were weakly associated with completeness of reporting, while neither traditional metric was related to methodological rigour. Our results suggest that high publication usage and journal outlet is not a guarantee of quality and readers should critically appraise all papers regardless of presumed impact. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted

  8. A Methodology for Measuring Voice Quality Using PESQ and Interactive Voice Response in the GSM Channel Designed by OpenBTS

    Directory of Open Access Journals (Sweden)

    Pavol Partila

    2013-01-01

    Full Text Available This article discusses a methodology for rating the quality of mobile calls. Majority telecommunications service from the perspective of the whole world is using mobile telephony networks. One of the problems affecting this service and its quality are landscape barriers, which prevent the spread signal. Price and complex construction of classic BTS does not allow their dense distribution. In such cases, one solution is to use OpenBTS technology. Design of OpenBTS is more available, so it can be applied to much more places and more complex points. Purpose of this measurement is a model for effective stations deployment, due to shape and distribution of local barriers that reduce signal power, and thus the quality of speech. GSM access point for our mobile terminals is OpenBTS USRP N210 station. The PESQ method for evaluating of speech quality is compared with the subjective evaluation, which provides Asterisk PBX with IVR call back. Measurement method was taken into account the call quality depending on terminal position. The measured results and its processing bring knowledge to use this technology for more complicated locations with degraded signal level and increases the quality of voice services in telecommunications.

  9. Permeability of shale at elevated temperature and pressure: Test methodology and preliminary results

    International Nuclear Information System (INIS)

    Myer, L.R.; Christian, T.L.

    1987-05-01

    A method of measuring the hydraulic conductivity of low permeability shale as a function of pressure and temperature has been developed and successfully demonstrated. Measurements have been performed on samples of Green River Formation up to a temperature of 140 0 C. For flow parallel to bedding hydraulic conductivities increased nonlinearly from 1.75 x 10 -16 m/s (1.6 x 10 -23 m 2 ) at 25 0 C, to 5.6 x 10 -15 m/s (1.4 x 10 -22 m 2 ) at 140 0 C. This increase in permeability with temperature may reflect an increase in microcrack porosity resulting from the heating

  10. Results of an innovative methodology to the dosimetry in mammography examinations

    International Nuclear Information System (INIS)

    Feital, J.C.S.; Delgado, J.U.; Peixoto, J.G.P.; Lopes, R.T.

    2015-01-01

    Female breast is a radiosensitive organ and the main procedure to assess the carcinogenic risk associated the mammographic practices has been indicated by the mean glandular dose (MGD) measurements. However, this dosimetric quantity may not provide the accuracy required for such measurements due to the heterogeneity of glandular tissue. So twenty-one exposures happened in a phantom mammographic using a CR equipment. Results were compared with data from the literature and was found an accuracy rate 15% lower than the recommended level. Experimental values reached below the IAEA's acceptable levels for 3.0 to 6.0 cm thickness of the compressed breast. (author)

  11. Attentional bias modification based on visual probe task: methodological issues, results and clinical relevance

    Directory of Open Access Journals (Sweden)

    Fernanda Machado Lopes

    2015-12-01

    Full Text Available Introduction: Attentional bias, the tendency that a person has to drive or maintain attention to a specific class of stimuli, may play an important role in the etiology and persistence of mental disorders. Attentional bias modification has been studied as a form of additional treatment related to automatic processing. Objectives: This systematic literature review compared and discussed methods, evidence of success and potential clinical applications of studies about attentional bias modification (ABM using a visual probe task. Methods: The Web of Knowledge, PubMed and PsycInfo were searched using the keywords attentional bias modification, attentional bias manipulation and attentional bias training. We selected empirical studies about ABM training using a visual probe task written in English and published between 2002 and 2014. Results: Fifty-seven studies met inclusion criteria. Most (78% succeeded in training attention in the predicted direction, and in 71% results were generalized to other measures correlated with the symptoms. Conclusions: ABM has potential clinical utility, but to standardize methods and maximize applicability, future studies should include clinical samples and be based on findings of studies about its effectiveness.

  12. Micro-PIXE analysis of fish otoliths. Methodology and evaluation of first results for stock discrimination

    International Nuclear Information System (INIS)

    Sie, S.H.; Thresher, R.E.

    1992-01-01

    Micro-PIXE has been used to measure the trace element distribution in otoliths from several species of ocean fish, in order to investigate its possible use in stock discrimination. Trace elements detected include Sr, Fe, Mn, Ni, Zn, Cu, Se, Cd, Br, Hg and Pb. Trace elements Na, K, Cl, S and Cl were detected with the electron microprobe. The high sensitivity of PIXE demands a meticulous sample preparation procedure to avoid contamination problems. Practical problems associated with the application of the technique were investigated in detail. Preliminary results indicate that most trace elements except Sr, are present at close to the limits of detection at few ppm, but biologically significant data can be obtained for stock discrimination applications. (author)

  13. Main results of German risk study, Phase B, in the light of methodological problems

    International Nuclear Information System (INIS)

    Koeberlein, K.

    1991-01-01

    The German Risk Study, Phase B, which has been performed for a 1,300 MWe KWU-type pressurized water reactor, is a level 2 probabilistic safety assessment (PSA). In the study, 32 initiating events have been considered. An expected plant damage state frequency of about 3x10 -5 per year has been calculated. In a plant damage state core meltdown can only be prevented by means of accident management procedures. The probability is high (about 98%) that in a plant damage state the primary system will not be depressurized. Core meltdown under high system pressure would endanger the containment integrity immediately. In most plant damage states accident management procedures are possible which bring the plant in a safe state or, at least, reduce the pressure in the primary system before the pressure vessel fails. On a preliminary basis, a success probability of 99% for accident management procedures (secondary or primary side bleed and feed) has been estimated. This results in an expected core melt frequency of about 4x10 -6 per year. The expected frequency of high pressure core meltdown is about 6x10 -7 per year. Loads on, and failure modes of, the containment during a core melt accident as well as release fractions after containment failure have been analyzed. The study did, however, refrain from quantifying the probability of containment failure modes. A main uncertainty in this area is the probability of containment failure due to hydrogen burning. The results of the study point out, that the risk can be reduced significantly if containment failure due to hydrogen burning can be reliably prevented

  14. METHODOLOGY AND RESULTS OF MOBILE OBJECT PURSUIT PROBLEM SOLUTION WITH TWO-STAGE DYNAMIC SYSTEM

    Directory of Open Access Journals (Sweden)

    A. Kiselev Mikhail

    2017-01-01

    Full Text Available The experience of developing unmanned fighting vehicles indicates that the main challenge in this field reduces itself to creating the systems which can replace the pilot both as a sensor and as the operator of the flight. This problem can be partial- ly solved by introducing remote control, but there are certain flight segments where it can only be executed under fully inde- pendent control and data support due to various reasons, such as tight time, short duration, lack of robust communication, etc. Such stages also include close-range air combat maneuvering (CRACM - a key flight segment as far as the fighter's purpose is concerned, which also places the highest demands on the fighter's design. Until recently the creation of an unmanned fighter airplane has been a fundamentally impossible task due to the absence of sensors able to provide the necessary data support to control the fighter during CRACM. However, the development prospects of aircraft hardware (passive type flush antennae, op- tico-locating panoramic view stations are indicative of producing possible solutions to this problem in the nearest future. There- fore, presently the only fundamental impediment on the way to developing an unmanned fighting aircraft is the problem of cre- ating algorithms for automatic trajectory control during CRACM. This paper presents the strategy of automatic trajectory con- trol synthesis by a two-stage dynamic system aiming to reach the conditions specified with respect to an object in pursuit. It contains certain results of control algorithm parameters impact assessment in regards to the pursuit mission effectiveness. Based on the obtained results a deduction is drawn pertaining to the efficiency of the offered method and its possible utilization in au- tomated control of an unmanned fighting aerial vehicle as well as organizing group interaction during CRACM.

  15. Methodological Considerations and Comparisons of Measurement Results for Extracellular Proteolytic Enzyme Activities in Seawater

    Directory of Open Access Journals (Sweden)

    Yumiko Obayashi

    2017-10-01

    Full Text Available Microbial extracellular hydrolytic enzymes that degrade organic matter in aquatic ecosystems play key roles in the biogeochemical carbon cycle. To provide linkages between hydrolytic enzyme activities and genomic or metabolomic studies in aquatic environments, reliable measurements are required for many samples at one time. Extracellular proteases are one of the most important classes of enzymes in aquatic microbial ecosystems, and protease activities in seawater are commonly measured using fluorogenic model substrates. Here, we examined several concerns for measurements of extracellular protease activities (aminopeptidases, and trypsin-type, and chymotrypsin-type activities in seawater. Using a fluorometric microplate reader with low protein binding, 96-well microplates produced reliable enzymatic activity readings, while use of regular polystyrene microplates produced readings that showed significant underestimation, especially for trypsin-type proteases. From the results of kinetic experiments, this underestimation was thought to be attributable to the adsorption of both enzymes and substrates onto the microplate. We also examined solvent type and concentration in the working solution of oligopeptide-analog fluorogenic substrates using dimethyl sulfoxide (DMSO and 2-methoxyethanol (MTXE. The results showed that both 2% (final concentration of solvent in the mixture of seawater sample and substrate working solution DMSO and 2% MTXE provide similarly reliable data for most of the tested substrates, except for some substrates which did not dissolve completely in these assay conditions. Sample containers are also important to maintain the level of enzyme activity in natural seawater samples. In a small polypropylene containers (e.g., standard 50-mL centrifugal tube, protease activities in seawater sample rapidly decreased, and it caused underestimation of natural activities, especially for trypsin-type and chymotrypsin-type proteases. In

  16. An inter-centre quality assurance network for IMRT verification: Results of the ESTRO QUASIMODO project

    International Nuclear Information System (INIS)

    Gillis, Sofie; Wagter, Carlos de; Bohsung, Joerg; Perrin, Bruce; Williams, Peter; Mijnheer, Ben J.

    2005-01-01

    Background and purpose: IMRT necessitates extension of existing inter-centre quality assurance programs due to its increased complexity. We assessed the feasibility of an inter-centre verification method for different IMRT techniques. Materials and methods: Eight European radiotherapy institutions of the QUASIMODO network, have designed an IMRT plan for a horseshoe-shaped PTV surrounding a cylindrical OAR in a simplified pelvic phantom. All centres applied common plan objectives but used their own equipment for planning and delivery. They verified the delivery of this plan according to a common protocol with radiographic film and ionisation chamber measurements. The irradiated films, the results of the ionisation chamber measurements and the computed dose distributions were sent to one analysis centre that compared the measured and computed dose distributions with the gamma method and composite dose-area histograms. Results: 4% (relative to the prescribed dose) and 3 mm (distance-to-agreement) were decided feasible gamma criteria. The composite dose-area histograms showed a maximum local deviation of 3.5% in the mean dose of the PTV and 5% in the OAR. Systematic differences could be identified, and in some cases explained. Conclusions: This multi-centre dosimetric verification study demonstrated both the feasibility of a multi-centre quality assurance network to evaluate any IMRT planning and delivery system combination, as well as the validity of the methodology involved

  17. GREET 1.5 - transportation fuel-cycle model - Vol. 1 : methodology, development, use, and results

    International Nuclear Information System (INIS)

    Wang, M. Q.

    1999-01-01

    This report documents the development and use of the most recent version (Version 1.5) of the Greenhouse Gases, Regulated Emissions, and Energy Use in Transportation (GREET) model. The model, developed in a spreadsheet format, estimates the full fuel-cycle emissions and energy associated with various transportation fuels and advanced vehicle technologies for light-duty vehicles. The model calculates fuel-cycle emissions of five criteria pollutants (volatile organic compounds, carbon monoxide, nitrogen oxides, particulate matter with diameters of 10 micrometers or less, and sulfur oxides) and three greenhouse gases (carbon dioxide, methane, and nitrous oxide). The model also calculates total energy consumption, fossil fuel consumption, and petroleum consumption when various transportation fuels are used. The GREET model includes the following cycles: petroleum to conventional gasoline, reformulated gasoline, conventional diesel, reformulated diesel, liquefied petroleum gas, and electricity via residual oil; natural gas to compressed natural gas, liquefied natural gas, liquefied petroleum gas, methanol, Fischer-Tropsch diesel, dimethyl ether, hydrogen, and electricity; coal to electricity; uranium to electricity; renewable energy (hydropower, solar energy, and wind) to electricity; corn, woody biomass, and herbaceous biomass to ethanol; soybeans to biodiesel; flared gas to methanol, dimethyl ether, and Fischer-Tropsch diesel; and landfill gases to methanol. This report also presents the results of the analysis of fuel-cycle energy use and emissions associated with alternative transportation fuels and advanced vehicle technologies to be applied to passenger cars and light-duty trucks

  18. A new paradigm for macromolecular crystallography beamlines derived from high-pressure methodology and results

    Energy Technology Data Exchange (ETDEWEB)

    Fourme, Roger, E-mail: roger.fourme@synchrotron-soleil.fr [Synchrotron SOLEIL, BP 48, Saint Aubin, 91192 Gif-sur-Yvette (France); Girard, Eric [IBS (UMR 5075 CEA-CNRS-UJF-PSB), 41 rue Jules Horowitz, 38027 Grenoble Cedex (France); Dhaussy, Anne-Claire [CRISMAT, ENSICAEN, 6 Boulevard du Maréchal Juin, 14000 Caen (France); Medjoubi, Kadda [Synchrotron SOLEIL, BP 48, Saint Aubin, 91192 Gif-sur-Yvette (France); Prangé, Thierry [LCRB (UMR 8015 CNRS), Université Paris Descartes, Faculté de Pharmacie, 4 avenue de l’Observatoire, 75270 Paris (France); Ascone, Isabella [ENSCP (UMR CNRS 7223), 11 rue Pierre et Marie Curie, 75231 Paris Cedex 05 (France); Mezouar, Mohamed [ESRF, BP 220, 38043 Grenoble (France); Kahn, Richard [IBS (UMR 5075 CEA-CNRS-UJF-PSB), 41 rue Jules Horowitz, 38027 Grenoble Cedex (France)

    2011-01-01

    Macromolecular crystallography at high pressure (HPMX) is a mature technique. Shorter X-ray wavelengths increase data collection efficiency on cryocooled crystals. Extending applications and exploiting spin-off of HPMX will require dedicated synchrotron radiation beamlines based on a new paradigm. Biological structures can now be investigated at high resolution by high-pressure X-ray macromolecular crystallography (HPMX). The number of HPMX studies is growing, with applications to polynucleotides, monomeric and multimeric proteins, complex assemblies and even a virus capsid. Investigations of the effects of pressure perturbation have encompassed elastic compression of the native state, study of proteins from extremophiles and trapping of higher-energy conformers that are often of biological interest; measurements of the compressibility of crystals and macromolecules were also performed. HPMX results were an incentive to investigate short and ultra-short wavelengths for standard biocrystallography. On cryocooled lysozyme crystals it was found that the data collection efficiency using 33 keV photons is increased with respect to 18 keV photons. This conclusion was extended from 33 keV down to 6.5 keV by exploiting previously published data. To be fully exploited, the potential of higher-energy photons requires detectors with a good efficiency. Accordingly, a new paradigm for MX beamlines was suggested, using conventional short and ultra-short wavelengths, aiming at the collection of very high accuracy data on crystals under standard conditions or under high pressure. The main elements of such beamlines are outlined.

  19. Testing for variation in taxonomic extinction probabilities: a suggested methodology and some results

    Science.gov (United States)

    Conroy, M.J.; Nichols, J.D.

    1984-01-01

    Several important questions in evolutionary biology and paleobiology involve sources of variation in extinction rates. In all cases of which we are aware, extinction rates have been estimated from data in which the probability that an observation (e.g., a fossil taxon) will occur is related both to extinction rates and to what we term encounter probabilities. Any statistical method for analyzing fossil data should at a minimum permit separate inferences on these two components. We develop a method for estimating taxonomic extinction rates from stratigraphic range data and for testing hypotheses about variability in these rates. We use this method to estimate extinction rates and to test the hypothesis of constant extinction rates for several sets of stratigraphic range data. The results of our tests support the hypothesis that extinction rates varied over the geologic time periods examined. We also present a test that can be used to identify periods of high or low extinction probabilities and provide an example using Phanerozoic invertebrate data. Extinction rates should be analyzed using stochastic models, in which it is recognized that stratigraphic samples are random varlates and that sampling is imperfect

  20. Interdepartmental interaction model on the extracurricular activities of students in the city of Surgut in the quality management system of the municipal state institution "Information and Methodological Center"

    OpenAIRE

    Loseva E. A.

    2018-01-01

    in this article the author considers interdepartmental interaction model in the field of extracurricular activities of students in the quality management system. The topic is examined on the example of the municipal state institution "Information and Methodological Center".

  1. GLOBAL MODELING OF NEBULAE WITH PARTICLE GROWTH, DRIFT, AND EVAPORATION FRONTS. I. METHODOLOGY AND TYPICAL RESULTS

    Energy Technology Data Exchange (ETDEWEB)

    Estrada, Paul R. [Carl Sagan Center, SETI Institute, 189 N. Bernardo Avenue # 100, Mountain View, CA 94043 (United States); Cuzzi, Jeffrey N. [Ames Research Center, NASA, Mail Stop 245-3, Moffett Field, CA 94035 (United States); Morgan, Demitri A., E-mail: Paul.R.Estrada@nasa.gov [USRA, NASA Ames Research Center, Mail Stop 245-3, Moffett Field, CA 94035 (United States)

    2016-02-20

    We model particle growth in a turbulent, viscously evolving protoplanetary nebula, incorporating sticking, bouncing, fragmentation, and mass transfer at high speeds. We treat small particles using a moments method and large particles using a traditional histogram binning, including a probability distribution function of collisional velocities. The fragmentation strength of the particles depends on their composition (icy aggregates are stronger than silicate aggregates). The particle opacity, which controls the nebula thermal structure, evolves as particles grow and mass redistributes. While growing, particles drift radially due to nebula headwind drag. Particles of different compositions evaporate at “evaporation fronts” (EFs) where the midplane temperature exceeds their respective evaporation temperatures. We track the vapor and solid phases of each component, accounting for advection and radial and vertical diffusion. We present characteristic results in evolutions lasting 2 × 10{sup 5} years. In general, (1) mass is transferred from the outer to the inner nebula in significant amounts, creating radial concentrations of solids at EFs; (2) particle sizes are limited by a combination of fragmentation, bouncing, and drift; (3) “lucky” large particles never represent a significant amount of mass; and (4) restricted radial zones just outside each EF become compositionally enriched in the associated volatiles. We point out implications for millimeter to submillimeter SEDs and the inference of nebula mass, radial banding, the role of opacity on new mechanisms for generating turbulence, the enrichment of meteorites in heavy oxygen isotopes, variable and nonsolar redox conditions, the primary accretion of silicate and icy planetesimals, and the makeup of Jupiter’s core.

  2. The BiPublishers ranking: Main results and methodological problems when constructing rankings of academic publishers

    Directory of Open Access Journals (Sweden)

    Torres-Salinas, Daniel

    2015-12-01

    Full Text Available We present the results of the Bibliometric Indicators for Publishers project (also known as BiPublishers. This project represents the first attempt to systematically develop bibliometric publisher rankings. The data for this project was derived from the Book Citation Index and the study time period was 2009-2013. We have developed 42 rankings: 4 by fields and 38 by disciplines. We display six indicators for publishers divided into three types: output, impact and publisher’s profile. The aim is to capture different characteristics of the research performance of publishers. 254 publishers were processed and classified according to publisher type: commercial publishers and university presses. We present the main publishers by field and then discuss the principal challenges presented when developing this type of tool. The BiPublishers ranking is an on-going project which aims to develop and explore new data sources and indicators to better capture and define the research impact of publishers.Presentamos los resultados del proyecto Bibliometric Indicators for Publishers (BiPublishers. Es el primer proyecto que desarrolla de manera sistemática rankings bibliométricos de editoriales. La fuente de datos empleada es el Book Citation Index y el periodo de análisis 2009-2013. Se presentan 42 rankings: 4 por áreas y 38 por disciplinas. Mostramos seis indicadores por editorial divididos según su tipología: producción, impacto y características editoriales. Se procesaron 254 editoriales y se clasificaron según el tipo: comerciales y universitarias. Se presentan las principales editoriales por áreas. Después, se discuten los principales retos a superar en el desarrollo de este tipo de herramientas. El ranking Bipublishers es un proyecto en desarrollo que persigue analizar y explorar nuevas fuentes de datos e indicadores para captar y definir el impacto de las editoriales académicas.

  3. GLOBAL MODELING OF NEBULAE WITH PARTICLE GROWTH, DRIFT, AND EVAPORATION FRONTS. I. METHODOLOGY AND TYPICAL RESULTS

    International Nuclear Information System (INIS)

    Estrada, Paul R.; Cuzzi, Jeffrey N.; Morgan, Demitri A.

    2016-01-01

    We model particle growth in a turbulent, viscously evolving protoplanetary nebula, incorporating sticking, bouncing, fragmentation, and mass transfer at high speeds. We treat small particles using a moments method and large particles using a traditional histogram binning, including a probability distribution function of collisional velocities. The fragmentation strength of the particles depends on their composition (icy aggregates are stronger than silicate aggregates). The particle opacity, which controls the nebula thermal structure, evolves as particles grow and mass redistributes. While growing, particles drift radially due to nebula headwind drag. Particles of different compositions evaporate at “evaporation fronts” (EFs) where the midplane temperature exceeds their respective evaporation temperatures. We track the vapor and solid phases of each component, accounting for advection and radial and vertical diffusion. We present characteristic results in evolutions lasting 2 × 10 5 years. In general, (1) mass is transferred from the outer to the inner nebula in significant amounts, creating radial concentrations of solids at EFs; (2) particle sizes are limited by a combination of fragmentation, bouncing, and drift; (3) “lucky” large particles never represent a significant amount of mass; and (4) restricted radial zones just outside each EF become compositionally enriched in the associated volatiles. We point out implications for millimeter to submillimeter SEDs and the inference of nebula mass, radial banding, the role of opacity on new mechanisms for generating turbulence, the enrichment of meteorites in heavy oxygen isotopes, variable and nonsolar redox conditions, the primary accretion of silicate and icy planetesimals, and the makeup of Jupiter’s core

  4. Implementation of a quality improvement initiative in Belgian diabetic foot clinics: feasibility and initial results.

    Science.gov (United States)

    Doggen, Kris; Van Acker, Kristien; Beele, Hilde; Dumont, Isabelle; Félix, Patricia; Lauwers, Patrick; Lavens, Astrid; Matricali, Giovanni A; Randon, Caren; Weber, Eric; Van Casteren, Viviane; Nobels, Frank

    2014-07-01

    This article aims to describe the implementation and initial results of an audit-feedback quality improvement initiative in Belgian diabetic foot clinics. Using self-developed software and questionnaires, diabetic foot clinics collected data in 2005, 2008 and 2011, covering characteristics, history and ulcer severity, management and outcome of the first 52 patients presenting with a Wagner grade ≥ 2 diabetic foot ulcer or acute neuropathic osteoarthropathy that year. Quality improvement was encouraged by meetings and by anonymous benchmarking of diabetic foot clinics. The first audit-feedback cycle was a pilot study. Subsequent audits, with a modified methodology, had increasing rates of participation and data completeness. Over 85% of diabetic foot clinics participated and 3372 unique patients were sampled between 2005 and 2011 (3312 with a diabetic foot ulcer and 111 with acute neuropathic osteoarthropathy). Median age was 70 years, median diabetes duration was 14 years and 64% were men. Of all diabetic foot ulcers, 51% were plantar and 29% were both ischaemic and deeply infected. Ulcer healing rate at 6 months significantly increased from 49% to 54% between 2008 and 2011. Management of diabetic foot ulcers varied between diabetic foot clinics: 88% of plantar mid-foot ulcers were off-loaded (P10-P90: 64-100%), and 42% of ischaemic limbs were revascularized (P10-P90: 22-69%) in 2011. A unique, nationwide quality improvement initiative was established among diabetic foot clinics, covering ulcer healing, lower limb amputation and many other aspects of diabetic foot care. Data completeness increased, thanks in part to questionnaire revision. Benchmarking remains challenging, given the many possible indicators and limited sample size. The optimized questionnaire allows future quality of care monitoring in diabetic foot clinics. Copyright © 2014 John Wiley & Sons, Ltd.

  5. Application of kaizen methodology to foster departmental engagement in quality improvement.

    Science.gov (United States)

    Knechtges, Paul; Decker, Michael Christopher

    2014-12-01

    The Toyota Production System, also known as Lean, is a structured approach to continuous quality improvement that has been developed over the past 50 years to transform the automotive manufacturing process. In recent years, these techniques have been successfully applied to quality and safety improvement in the medical field. One of these techniques is kaizen, which is the Japanese word for "good change." The central tenant of kaizen is the quick analysis of the small, manageable components of a problem and the rapid implementation of a solution with ongoing, real-time reassessment. Kaizen adds an additional "human element" that all stakeholders, not just management, must be involved in such change. Because of the small size of the changes involved in a kaizen event and the inherent focus on human factors and change management, a kaizen event can serve as good introduction to continuous quality improvement for a radiology department. Copyright © 2014. Published by Elsevier Inc.

  6. [Quality of life - methodology and clinical practice aspects with a focus on ocular medicine].

    Science.gov (United States)

    Franke, G H; Gall, C

    2008-08-01

    Due to the demographic development in western industrialised countries, the proportion of visually impaired persons is likely to increase in the future. Currently there is a shift in scientific recognition from relative neglect of psychopathological distress in the visually impaired to better notice of disease-related subjective impairments that are detectable with specific questionnaire measures. Visual acuity primarily determines the subjective rating of visual functioning independent from the eye disease. Ophthalmic patients who show only mild symptoms from a medical point of view normally suffer considerably diminished vision-related quality of life with respect to physical, functional, mental, and social aspects. Treatment effects have been shown using vision-related quality-of-life measures for different ophthalmic diseases, particularly cataract surgery. Assessment of vision-related quality of life provides a meaningful complement to objective data.

  7. Urethral obstruction after anti-incontinence surgery in women: evaluation, methodology, and surgical results.

    Science.gov (United States)

    Austin, P; Spyropoulos, E; Lotenfoe, R; Helal, M; Hoffman, M; Lockhart, J L

    1996-06-01

    To evaluate a group of women with voiding dysfunction and a low maximum flow rate (MFR) (less than or equal to 12 mL/s) after surgery for stress urinary incontinence (SUI); to establish diagnostic parameters indicating obstruction in an attempt to determine treatment selection; and to evaluate preliminary surgical results. Eighteen women who underwent anti-incontinence surgery for SUI were diagnosed as having infravesical obstruction (IO). Thirteen women (group A [72%]) presented with clinically predominant symptoms of urgency, frequency, intermittency, and a variable vesical residual volume (RV), and five (group B [28%]) had as their most significant symptoms a high vesical RV and urinary tract infection that had been managed with intermittent catheterization (IC). The diagnosis of IO, suspected after clinical history, was established after physical examination and cystoscopic, cystographic and urodynamic investigations. Bladder instability was demonstrated in 6 group A patients (46%) and 1 group B patient (20%) (P = NS). Mean MFRs were 8.07 and 7.2 mL/s, respectively, in both groups (P = NS). Mean maximal voiding pressures (MVPs) were 20.23 and 5 cm H20, and mean RVs were 57.46 and 174 mL, respectively; both differences were statistically very significant (P <0.01 and P <0.001, respectively). High to normal MVPs occurred in 2 patients overall (11%). Bladder neck overcorrection, midurethral distortion, and postsurgical cystocele were demonstrated in both groups in 11 (85%), 0, and 2 (15%) patients in group A and 3 (60%), 2 (40%), and 3 (60%) patients in group B, respectively (P = NS). Patients in group A were treated surgically with cystourethrolysis and a repeated, less obstructive anti-incontinence operation. In group B 2 women (40%) had a similar surgical procedure; 1 (20%) underwent isolated urethrolysis; and 2 (40%) are currently maintained with IC. Among these 18 patients with voiding dysfunction after anti-incontinence surgery, a primary diagnosis of IO was

  8. New methodology to implement quality control programs in medical imaging departments

    International Nuclear Information System (INIS)

    Furquim, Tania A.C.; Yanikian, Denise; Costa, Paulo R.

    1996-01-01

    The implementation of quality control programmes is studied in order to assure a better performance in medical imaging departments. The necessity of a continuous training of all technicians involved is highlighted. The contribution of these professionals is emphasized as fundamental to the success of the project

  9. Quality approach in in vivo nuclear medicine - Certification V2010 - Methodological guide

    International Nuclear Information System (INIS)

    Abdelmoumene, Nafissa; Ferreol, Dominique; Blondet, Emmanuelle; Bonardel, Gerald; Bourrel, Francois; Broglia, Jean Marc; Guilabert, Nadine; Israel, Jean-Marc; Machacek, Catherine; Martineau, Antoine; Remy, Herve; Rousseliere, Francis; Abelmann, Caroline

    2013-01-01

    This document first presents the different components of the activity in in-vivo nuclear medicine: techniques (functional imagery, vectorized internal radiotherapy, cases outside the nuclear medicine department), team composition and missions, radiation protection regulations, benefits and risks. Then, it addresses the quality approach: quality management system defined according to a process-oriented approach, documentation. It proposes a sheet to assess the implementation of the quality approach. This sheet contains 129 criteria which are related to management (strategy, activity steering and coordination), to support functions (management of human resources and abilities, management of radioactive sources and wastes, radio-pharmacy within the nuclear medicine department, management of medical devices, information system), to patient taking on (management of appointments and patient identification, imagery examination justification, patient reception, patients presenting risks and peculiar situations, checking before radio-pharmaceutical drug administering, taking on for diagnosis purpose, taking for therapeutic purposes), and to assessment, analysis and improvement (management of undesirable events associated with cares, quality follow-up for continuous improvement)

  10. Interrelationships between man, energy, and water quality: a new methodology for integrative analyses

    International Nuclear Information System (INIS)

    Kaplan, E.; Thode, H.C. Jr.

    1979-01-01

    The STORET/MSP option was used to obtain county aggregated information on ambient water quality for sixty parameters during the period 1950 to 1978. Masks, extended EXTRACT specifications and bounds on allowable values limited inclusion of erroneous data. Remark codes were required to aggregate STORET parameters to obtain increased numbers of observations. Numerous statistical analyses led to the conclusions that medians were more useful than means, that trimming on number of observations was required to eliminate counties with extreme values, and that many parameters required logarithmic transformation to be useful in regional analyses. County aggregated data for nineteen water quality parameters were examined in terms of their ability to describe qualitative chemical characteristics of water. Anion--cation balances as well as expected relationships between conductivity and other parameters were correctly accounted for. Factor analysis indicated the existence of three principal components describing patterns between metal ions, non-metal ions, and alkalinity-bicarbonate, respectively. These factors were used in place of the original complete set of water quality parameters in a structural equation approach describing relationships between variables of mans activites. It was found that counties with high industrial electric consumption, farming and mineral shipments tended to have increased levels of most water quality parameters. It was also found that simpler path diagrams may be indicated to reduce the effects of redundancy in adequately describing energy--water relationships

  11. Control Charts in Healthcare Quality Improvement A Systematic Review on Adherence to Methodological Criteria

    NARCIS (Netherlands)

    Koetsier, A.; van der Veer, S. N.; Jager, K. J.; Peek, N.; de Keizer, N. F.

    2012-01-01

    Objectives: Use of Shewhart control charts in quality improvement (QI) initiatives is increasing. These charts are typically used in one or more phases of the Plan Do Study Act (PDSA) cycle to monitor summaries of process and outcome data, abstracted from clinical information systems, over time. We

  12. An evaluation of contaminated estuarine sites using sediment quality guidelines and ecological assessment methodologies.

    Science.gov (United States)

    Fulton, M; Key, P; Wirth, E; Leight, A K; Daugomah, J; Bearden, D; Sivertsen, S; Scott, G

    2006-10-01

    Toxic contaminants may enter estuarine ecosystems through a variety of pathways. When sediment contaminant levels become sufficiently high, they may impact resident biota. One approach to predict sediment-associated toxicity in estuarine ecosystems involves the use of sediment quality guidelines (ERMs, ERLs) and site-specific contaminant chemistry while a second approach utilizes site-specific ecological sampling to assess impacts at the population or community level. The goal of this study was to utilize an integrated approach including chemical contaminant analysis, sediment quality guidelines and grass shrimp population monitoring to evaluate the impact of contaminants from industrial sources. Three impacted sites and one reference site were selected for study. Grass shrimp populations were sampled using a push-netting approach. Sediment samples were collected at each site and analyzed for metals, polycyclic aromatic hydrocarbons (PAHs), polychlorinated biphenyls (PCBs) and pesticides. Contaminant levels were then compared to sediment quality guidelines. In general, grass shrimp population densities at the sites decreased as the ERM quotients increased. Grass shrimp densities were significantly reduced at the impacted site that had an ERM exceedance for chromium and the highest Mean ERM quotient. Regression analysis indicated that sediment chromium concentrations were negatively correlated with grass shrimp density. Grass shrimp size was reduced at two sites with intermediate levels of contamination. These findings support the use of both sediment quality guidelines and site-specific population monitoring to evaluate the impacts of sediment-associated contaminants in estuarine systems.

  13. Combining Statistical Methodologies in Water Quality Monitoring in a Hydrological Basin - Space and Time Approaches

    OpenAIRE

    Costa, Marco; A. Manuela Gonçalves

    2012-01-01

    In this work are discussed some statistical approaches that combine multivariate statistical techniques and time series analysis in order to describe and model spatial patterns and temporal evolution by observing hydrological series of water quality variables recorded in time and space. These approaches are illustrated with a data set collected in the River Ave hydrological basin located in the Northwest region of Portugal.

  14. Quantitative analysis of results for quality assurance in radiotherapy

    International Nuclear Information System (INIS)

    Passaro, Bruno Martins

    2011-01-01

    The linear accelerators represent the most important, practical and versatile source of ionizing radiation in radiotherapy. These functional characteristics influence the geometric and dosimetric accuracy of therapeutic doses applied to patients. The performance of this equipment may vary due to electronic defects, component failures or mechanical breakdowns, or may vary due to the deterioration and aging of components. Maintaining the quality of care depends on the stability of the accelerators and quality control of the institutions to monitor deviations in the parameters of the beam. The aim of this study is to assess and analyze the stability of the calibration factor of linear accelerators, as well as the other dosimetric parameters normally included in a program of quality control in radiotherapy. The average calibration factors of the accelerators for the period of approximately four years for the Clinac 600C and Clinac 6EX were (0,998 ± 0,012) and (0,996 ± 0,014), respectively. For the Clinac 2100CD 6 MV and 15 MV was (1,008 ± 0,009) and (1,006 ± 0,010), respectively, in a period of approximately four years. Statistical analysis of the three linear accelerators was found that the coefficient of variation of calibration factors had values below 2% which shows a consistency in the data. By calculating the normal distribution of calibration factors, we found that for the Clinac 600C and Clinac 2100CD, is an expected probability that more than 90% of cases the values are within acceptable limits according to the TG-142, while for the Clinac 6EX is expected around 85% since this had several exchanges of accelerator components. The values of TPR 20,10 of three accelerators are practically constant and within acceptable limits according to the TG-142. It can be concluded that a detailed study of data from the calibration factor of the accelerators and TPR20,10 from a quantitative point of view, is extremely useful in a quality assurance program. (author)

  15. Modelling the effects of transglutaminase and L-ascorbic acid on substandard quality wheat flour by response surface methodology

    Directory of Open Access Journals (Sweden)

    Šimurina Olivera D.

    2014-01-01

    Full Text Available In recent decade, there have been observed extreme variations in climatic conditions which in combination with inadequate agro techniques lead to decreased quality of mercantile wheat, actally flour. The application of improvers can optimise the quality of substandard wheat flour. This paper focuses to systematic analysis of individual and interaction effects of ascorbic acid and transglutaminase as dough strengthening improvers. The effects were investigated using the Response Surface Methodology. Transglutaminase had much higher linear effect on the rheological and fermentative properties of dough from substandard flour than L-ascorbic acid. Both transglutaminase and L-ascorbic acid additions had a significant linear effect on the increase of bread specific volume. Effects of transglutaminase and ascorbic acid are dependent on the applied concentrations and it is necessary to determine the optimal concentration in order to achieve the maximum quality of the dough and bread. Optimal levels of tested improvers were determined using appropriate statistical techniques which applied the desirability function. It was found that the combination of 30 mg/kg of transglutaminase and 75.8 mg/kg of L-ascorbic acid achieved positive synergistic effect on rheological and fermentative wheat dough properties, as well on textural properties and specific volume of bread made from substandard quality flour.

  16. Evaluation of chips quality by the analysis of two different harvesting methodologies

    Energy Technology Data Exchange (ETDEWEB)

    Pari, L.; Civitarese, V.; Del Giudice, A. [Council for Research in Agriculture, Agricultural Engineering Research Unit, Rome (Italy)

    2010-07-01

    The Council for Research in Agriculture, Agricultural Engineering Research Unit (CRA-ING) in Rome, Italy has developed an innovative short-rotation forestry (SRF) harvesting system. The system involves a 2 step operation, notably the tree felling and inter-row windrowing performed by a feller windrower equipment; and subsequent chipping performed by a harvester equipped with a pick-up device. The low moisture content of the windrowed trees at harvesting time affects their physical qualities and mechanical strength throughout the chipping operation. The purpose of this study was to analyze the moisture losses of windrowed trees, in relation to the windrow location, on field storage and weather condition. In addition, the study characterized chips quality changes during on field storage by the 2 different harvesting systems. The innovative 2-step system was compared with the traditional 1-step harvesting system.

  17. Methodology for the construction of a physical phantom for quality control of images in digital radiography

    International Nuclear Information System (INIS)

    Santos, Tayline T.; Vieira, Jose Wilson; Oliveira, Alex Cristovao H. de; Lima, Fernando R. de Andrade

    2013-01-01

    The advancement of technology in recent years has provided the production of increasingly sophisticated devices, aiming to acquire medical images with high technical level and also facilitate the operational readiness of the equipment. In order to ensure the most accurate diagnosis with minimum dose without exposing patients to obtain data and verify the performance of a radiographic system for quality control purposes we use the so-called phantoms. Phantoms are physical or computational models used to simulate the transport of ionizing radiation, their interactions in the tissues of the human body and evaluate the deposition of energy. Besides, they are made from materials with behavior similar to human tissues when exposed to ionizing radiation - the so-called tissue-equivalent materials. This paper describes the construction of a physical phantom that allows the execution of the main acceptance tests of the quality control protocols in digital radiography

  18. Upscaling laboratory results for water quality prediction at underground collieries in South Africa's Highveld Coalfields

    Energy Technology Data Exchange (ETDEWEB)

    Usher, B.H. [University of Orange Free State, Bloemfontein (South Africa). Institute for Groundwater Studies

    2009-01-15

    The prediction of future acidity and water quality is a key aspect of water management in mining environments. In this paper, different prediction techniques tested in an isolated underground compartment at a colliery in the Highveld Coalfield of South Africa are discussed. Considerations for upscaling these results are explained, and a methodology for upscaling is tested at this facility. Over 30 samples were collected around the compartment and through cored boreholes. These samples were tested using acid-base accounting tests, humidity cells, and mineralogy. From this, an integrated interpretation of potential water quality evolution was made, supported by detailed water quality sampling with the use of surface boreholes, stratified sampling underground, and pumped qualities over a period of two years. The results show that analytical tests play an integral role in water quality predictions at underground collieries. The results also show that, despite the vast differences between laboratory test conditions and the situation in the field, by taking site conditions into account to properly contextualise the results, improved predictions of expected water quality can be obtained.

  19. Verification results of methodology for determining the weighted mean coolant temperature in the primary circuit hot legs of WWER-1000 reactor plants

    Energy Technology Data Exchange (ETDEWEB)

    Saunin, Yuri V.; Dobrotvorski, Alexander N.; Semenikhin, Alexander V.; Korolev, Alexander S. [JSC ' ' Atomtechenergo' ' , Novovoronezh (Russian Federation). Novovoronezh Filial ' ' Novovoronezhatomtechenergo' ' ; Ryasny, Sergei I. [JSC ' ' Atomtechenergo' ' , Moscow (Russian Federation)

    2017-09-15

    The JSC ''Atomtechenergo'' experts have developed a new methodology for determining the weighted mean coolant temperature in the primary circuit hot legs of WWER-1000 reactor plants. The necessity for developing the new methodology was determined by the need to decrease the calculation error of the weighted mean coolant temperature in the hot legs because of the coolant temperature stratification. The methodology development was based on the findings of experimental and calculating research executed by the authors. The methodology verification was fulfilled through comparison of calculation results obtained with and without the methodology use in various operational states and modes of several WWER-1000 power units. The obtained verification results have confirmed that the use of the new methodology provides objective error decrease in determining the weighted mean coolant temperature in the primary circuit hot legs. The decrease value depends on the stratification character which is various for different objects and conditions.

  20. Verification results of methodology for determining the weighted mean coolant temperature in the primary circuit hot legs of WWER-1000 reactor plants

    International Nuclear Information System (INIS)

    Saunin, Yuri V.; Dobrotvorski, Alexander N.; Semenikhin, Alexander V.; Korolev, Alexander S.

    2017-01-01

    The JSC ''Atomtechenergo'' experts have developed a new methodology for determining the weighted mean coolant temperature in the primary circuit hot legs of WWER-1000 reactor plants. The necessity for developing the new methodology was determined by the need to decrease the calculation error of the weighted mean coolant temperature in the hot legs because of the coolant temperature stratification. The methodology development was based on the findings of experimental and calculating research executed by the authors. The methodology verification was fulfilled through comparison of calculation results obtained with and without the methodology use in various operational states and modes of several WWER-1000 power units. The obtained verification results have confirmed that the use of the new methodology provides objective error decrease in determining the weighted mean coolant temperature in the primary circuit hot legs. The decrease value depends on the stratification character which is various for different objects and conditions.

  1. Measurement of environmental impacts of telework adoption amidst change in complex organizations. AT and T survey methodology and results

    Energy Technology Data Exchange (ETDEWEB)

    Atkyns, Robert; Blazek, Michele; Roitz, Joseph [AT and T, 179 Bothin Road, 94930 Fairfax, CA (United States)

    2002-10-01

    Telecommuting practices and their environmental and organizational performance impacts have stimulated research across academic disciplines. Although telecommuting trends and impact projections are reported, few true longitudinal studies involving large organizations have been conducted. Published studies typically lack the research design elements to control a major confounding variable: rapid and widespread organizational change. Yet social science 'Best Practices' and market research industry quality control procedures exist that can help manage organizational change effects and other common sources of measurement error. In 1992, AT and T established a formal, corporate-wide telecommuting policy. A research and statistical modeling initiative was implemented to measure how flexible work arrangements reduce automotive emissions. Annual employee surveys were begun in 1994. As telecommuting benefits have been increasingly recognized within AT and T, the essential construct has been redefined as 'telework.' The survey's scope has expanded to address broader organization issues and provide guidance to multiple internal constituencies. This paper focuses upon the procedures used to reliably measure the adoption of telework practices and model their environmental impact, and contrasts those procedures with other, less reliable methodologies.

  2. Methodology for setup and data processing of mobile air quality measurements to assess the spatial variability of concentrations in urban environments

    International Nuclear Information System (INIS)

    Van Poppel, Martine; Peters, Jan; Bleux, Nico

    2013-01-01

    A case study is presented to illustrate a methodology for mobile monitoring in urban environments. A dataset of UFP, PM 2.5 and BC concentrations was collected. We showed that repeated mobile measurements could give insight in spatial variability of pollutants at different micro-environments in a city. Streets of contrasting traffic intensity showed increased concentrations by a factor 2–3 for UFP and BC and by 2.5 . The first quartile (P25) of the mobile measurements at an urban background zone seems to be good estimate of the urban background concentration. The local component of the pollutant concentrations was determined by background correction. The use of background correction reduced the number of runs needed to obtain representative results. The results presented, are a first attempt to establish a methodology for setup and data processing of mobile air quality measurements to assess the spatial variability of concentrations in urban environments. -- Highlights: ► Mobile measurements are used to assess the variability of air pollutants in urban environments. ► PM 2.5 , BC and UFP concentrations are presented for zones with different traffic characteristics. ► A methodology for background correction based on the mobile measurements is presented. ► The background concentration is estimated as the 25th percentile of the urban background data. ► The minimum numbers of runs for a representative estimate is reduced after background correction. -- This paper shows that the spatial variability of air pollutants in an urban environment can be assessed by a mobile monitoring methodology including background correction

  3. Computer Class Role Playing Games, an innovative teaching methodology based on STEM and ICT: first experimental results

    Science.gov (United States)

    Maraffi, S.

    2016-12-01

    Context/PurposeWe experienced a new teaching and learning technology: a Computer Class Role Playing Game (RPG) to perform educational activity in classrooms through an interactive game. This approach is new, there are some experiences on educational games, but mainly individual and not class-based. Gaming all together in a class, with a single scope for the whole class, it enhances peer collaboration, cooperative problem solving and friendship. MethodsTo perform the research we experimented the games in several classes of different degrees, acquiring specific questionnaire by teachers and pupils. Results Experimental results were outstanding: RPG, our interactive activity, exceed by 50% the overall satisfaction compared to traditional lessons or Power Point supported teaching. InterpretationThe appreciation of RPG was in agreement with the class level outcome identified by the teacher after the experimentation. Our work experience get excellent feedbacks by teachers, in terms of efficacy of this new teaching methodology and of achieved results. Using new methodology more close to the student point of view improves the innovation and creative capacities of learners, and it support the new role of teacher as learners' "coach". ConclusionThis paper presents the first experimental results on the application of this new technology based on a Computer game which project on a wall in the class an adventure lived by the students. The plots of the actual adventures are designed for deeper learning of Science, Technology, Engineering, Mathematics (STEM) and Social Sciences & Humanities (SSH). The participation of the pupils it's based on the interaction with the game by the use of their own tablets or smartphones. The game is based on a mixed reality learning environment, giving the students the feel "to be IN the adventure".

  4. Palliative healthcare: cost reduction and quality enhancement using end-of-life survey methodology.

    Science.gov (United States)

    Falls, Christopher Edward

    2008-01-01

    American medical institutions throughout the 20th century prescribed high customer satisfaction, but when it came to death, largely ignored it. An accelerated accumulation of esoteric medical information and the application of this knowledge to affect new cures and longer lives instilled an unquestioning reverence for the medical community among the patient population. Diminishing marginal gains in life expectancy, escalating costs related to life sustaining technologies, and a psychographic shift in the dominant consumer base have challenged this traditional reverence. Armed with unprecedented access to medical information, a more knowledgeable and assertive patient population has emerged in the 21st century to institute its own standards of what constitutes quality health care. In terms of end of life care, this has meant recognition that the emotional needs of the dying have been largely underserved by the current American medical model. Patients and their families are no longer willing to accept the traditional medical perspective of death as failure and have numerous international palliative care models that serve as benchmarks of success when it comes to quality of dying. When cure is a possibility, Americans will pursue it at all costs, but when it is not a possibility, they want honest communication and the opportunity to say good-bye to their loved ones. In the context of these emergent needs, life review is offered as a solution. The value proposition targets not only dying patients and their families, but also society as a whole.

  5. Non-Communicable Disease Clinical Practice Guidelines in Brazil: A Systematic Assessment of Methodological Quality and Transparency.

    Directory of Open Access Journals (Sweden)

    Caroline de Godoi Rezende Costa Molino

    Full Text Available Annually, non-communicable diseases (NCDs kill 38 million people worldwide, with low and middle-income countries accounting for three-quarters of these deaths. High-quality clinical practice guidelines (CPGs are fundamental to improving NCD management. The present study evaluated the methodological rigor and transparency of Brazilian CPGs that recommend pharmacological treatment for the most prevalent NCDs.We conducted a systematic search for CPGs of the following NCDs: asthma, atrial fibrillation, benign prostatic hyperplasia, chronic obstructive pulmonary disease, congestive heart failure, coronary artery disease and/or stable angina, dementia, depression, diabetes, gastroesophageal reflux disease, hypercholesterolemia, hypertension, osteoarthritis, and osteoporosis. CPGs comprising pharmacological treatment recommendations were included. No language or year restrictions were applied. CPGs were excluded if they were merely for local use and referred to NCDs not listed above. CPG quality was independently assessed by two reviewers using the Appraisal of Guidelines Research and Evaluation instrument, version II (AGREE II."Scope and purpose" and "clarity and presentation" domains received the highest scores. Sixteen of 26 CPGs were classified as low quality, and none were classified as high overall quality. No CPG was recommended without modification (77% were not recommended at all. After 2009, 2 domain scores ("rigor of development" and "clarity and presentation" increased (61% and 73%, respectively. However, "rigor of development" was still rated < 30%.Brazilian healthcare professionals should be concerned with CPG quality for the treatment of selected NCDs. Features that undermined AGREE II scores included the lack of a multidisciplinary team for the development group, no consideration of patients' preferences, insufficient information regarding literature searches, lack of selection criteria, formulating recommendations, authors' conflict of

  6. Current discharge management of acute coronary syndromes: baseline results from a national quality improvement initiative.

    Science.gov (United States)

    Wai, A; Pulver, L K; Oliver, K; Thompson, A

    2012-05-01

    Evidence-practice gaps exist in the continuum of care for patients with acute coronary syndromes (ACS), particularly at hospital discharge. We aimed to describe the methodology and baseline results of the Discharge Management of Acute Coronary Syndromes (DMACS) project, focusing on the prescription of guideline-recommended medications, referral to cardiac rehabilitation and communication between the hospital, patient and their primary healthcare professionals. DMACS employed Drug Use Evaluation methodology involving data collection, evaluation and feedback, and targeted educational interventions. Adult patients with ACS discharged during a 4-month period were eligible to participate. Data were collected (maximum 50 patients) at each site through an inpatient medical record review, a general practitioner (GP) postal/fax survey conducted 14 days post discharge and a patient telephone survey 3 months post discharge. Forty-nine hospitals participated in the audit recruiting 1545 patients. At discharge, 57% of patients were prescribed a combination of antiplatelet agent(s), beta-blocker, statin and angiotensin-converting enzyme inhibitor and/or angiotensin II-antagonist. At 3 months post discharge, 48% of patients reported using the same combination. Some 67% of patients recalled being referred to cardiac rehabilitation; of these, 33% had completed the programme. In total, 83% of patients had a documented ACS management plan at discharge. Of these, 90% included a medication list, 56% a chest pain action plan and 54% risk factor modification advice. Overall, 65% of GPs rated the quality of information received in the discharge summary as 'very good' to 'excellent'. The findings of our baseline audit showed that despite the robust evidence base and availability of national guidelines, the management of patients with ACS can be improved. These findings will inform a multifaceted intervention strategy to improve adherence to guidelines for the discharge management of

  7. Application of the PISC results and methodology to assess the effectiveness of NDT techniques applied on non nuclear components

    International Nuclear Information System (INIS)

    Maciga, G.; Papponetti, M.; Crutzen, S.; Jehenson, P.

    1990-01-01

    Performance demonstration for NDT has been an active topic for several years. Interest in it came to the fore in the early 1980's when several institutions started to propose to use of realistic training assemblies and the formal approach of Validation Centers. These steps were justified for example by the results of the PISC exercises which concluded that there was a need for performance demonstration starting with capability assessment of techniques and procedure as they were routinely applied. If the PISC programme is put under the general ''Nuclear Motivation'', the PISC Methodology could be extended to problems to structural components in general, such as on conventional power plants, chemical, aerospace and offshore industries, where integrity and safety have regarded as being of great importance. Some themes of NDT inspections of fossil power plant and offshore components that could be objects of validation studies will be illustrated. (author)

  8. Results of a Research Evaluating Quality of Computer Science Education

    Science.gov (United States)

    Záhorec, Ján; Hašková, Alena; Munk, Michal

    2012-01-01

    The paper presents the results of an international research on a comparative assessment of the current status of computer science education at the secondary level (ISCED 3A) in Slovakia, the Czech Republic, and Belgium. Evaluation was carried out based on 14 specific factors gauging the students' point of view. The authors present qualitative…

  9. Artificial intelligence methodologies applied to quality control of the positioning services offered by the Red Andaluza de Posicionamiento (RAP network

    Directory of Open Access Journals (Sweden)

    Antonio José Gil

    2012-12-01

    Full Text Available On April 26, 2012, Elena Giménez de Ory defend-ed her Ph.D. thesis at University of Jaén, entitled: “Robust methodologies applied to quality control of the positioning services offered by the Red Andaluza de Posicionamiento (RAP network”. Elena Giménez de Ory defended her dissertation in a publicly open presentation held in the Higher Polytechnic School at the University of Jaén, and was able to comment on every question raised by her thesis committee and the audience. The thesis was supervised by her advisor, Prof. Antonio J. Gil Cruz, and the rest of his thesis committee, Prof. Manuel Sánchez de la Orden, Dr. Antonio Miguel Ruiz Armenteros and Dr. Gracia Rodríguez Caderot. The thesis has been read and approved by his thesis committee, receiving the highest rating. All of them were present at the presentation.

  10. A systematic and transparent approach for assessing the methodological quality of intervention effectiveness research: the Study Design and Implementation Assessment Device (Study DIAD).

    Science.gov (United States)

    Valentine, Jeffrey C; Cooper, Harris

    2008-06-01

    Assessments of studies meant to evaluate the effectiveness of interventions, programs, and policies can serve an important role in the interpretation of research results. However, evidence suggests that available quality assessment tools have poor measurement characteristics and can lead to opposing conclusions when applied to the same body of studies. These tools tend to (a) be insufficiently operational, (b) rely on arbitrary post-hoc decision rules, and (c) result in a single number to represent a multidimensional construct. In response to these limitations, a multilevel and hierarchical instrument was developed in consultation with a wide range of methodological and statistical experts. The instrument focuses on the operational details of studies and results in a profile of scores instead of a single score to represent study quality. A pilot test suggested that satisfactory between-judge agreement can be obtained using well-trained raters working in naturalistic conditions. Limitations of the instrument are discussed, but these are inherent in making decisions about study quality given incomplete reporting and in the absence of strong, contextually based information about the effects of design flaws on study outcomes. (PsycINFO Database Record (c) 2008 APA, all rights reserved).

  11. Better Data Quality for Better Healthcare Research Results - A Case Study.

    Science.gov (United States)

    Hart, Robert; Kuo, Mu-Hsing

    2017-01-01

    Electronic Health Records (EHRs) have been identified as a key tool to collect data for healthcare research. However, EHR data must be of sufficient quality to support quality research results. Island Health, BC, Canada has invested and continues to invest in the development of solutions to address the quality of its EHR data and support high quality healthcare studies. This paper examines Island Health's data quality engine, its development and its successful implementation.

  12. Measurement results obtained from air quality monitoring system

    Energy Technology Data Exchange (ETDEWEB)

    Turzanski, P.K.; Beres, R. [Provincial Inspection of Environmental Protection, Cracow (Poland)

    1995-12-31

    An automatic system of air pollution monitoring operates in Cracow since 1991. The organization, assembling and start-up of the network is a result of joint efforts of the US Environmental Protection Agency and the Cracow environmental protection service. At present the automatic monitoring network is operated by the Provincial Inspection of Environmental Protection. There are in total seven stationary stations situated in Cracow to measure air pollution. These stations are supported continuously by one semi-mobile (transportable) station. It allows to modify periodically the area under investigation and therefore the 3-dimensional picture of creation and distribution of air pollutants within Cracow area could be more intelligible.

  13. Study of physical properties of UO2 quality improvement result

    International Nuclear Information System (INIS)

    Rachmat-Pratomo; Hidayati; Didiek Herhady, R; Busron-Masduki

    1996-01-01

    Activation of uranium dioxide (UO 2 ) by reoxidation to U 3 O 8 and reduction to uranium dioxide (UO 2 ) by temperature reduction variation of 850 o C and 900 o C for 3 hours has been studied. The physical properties before and after treatment are compared. It proved that the oxidation-reduction cycle increased the physical properties. It can be concluded that the reoxidation of UO 2 to U 3 O 8 on fourth cycle and reduction at 900 o C for 3 hours result in a density of 1.32 gram/ml a tap density of 1.60 gram/ml, true density of 9.08 gram/ml and O/U ratio : 2.04. Reduction at 850 o C, for 3 hours result in the bulk density of 1.30 gram/ml, tap density of 1.58 gram/ml, true density of 9.04 gram/ml and O/U ratio 2.09

  14. Experiments with a methodology to model the role of R and D expenditures in energy technology learning processes; first results

    International Nuclear Information System (INIS)

    Miketa, Asami; Schrattenholzer, Leo

    2004-01-01

    This paper presents the results of using a stylized optimization model of the global electricity supply system to analyze the optimal research and development (R and D) support for an energy technology. The model takes into account the dynamics of technological progress as described by a so-called two-factor learning curve (2FLC). The two factors are cumulative experience ('learning by doing') and accumulated knowledge ('learning by searching'); the formulation is a straightforward expansion of conventional one-factor learning curves, in which only cumulative experience is included as a factor, which aggregates the effects of accumulated knowledge and cumulative experience, among others. The responsiveness of technological progress to the two factors is quantified using learning parameters, which are estimated using empirical data. Sensitivities of the model results to the parameters are also tested. The model results also address the effect of competition between technologies and of CO 2 constraints. The results are mainly methodological; one of the most interesting is that, at least up to a point, competition between technologies - in terms of both market share and R and D support - need not lead to 'lock-in' or 'crowding-out'

  15. Experiments with a methodology to model the role of R and D expenditures in energy technology learning processes: first results

    International Nuclear Information System (INIS)

    Miketa, A.; Schrattenholzer, L.

    2004-01-01

    This paper presents the results of using a stylized optimization model of the global electricity supply system to analyze the optimal research and development (R and D) support for an energy technology. The model takes into account the dynamics of technological progress as described by a so-called two-factor learning curve (2FLC). The two factors are cumulative experience (''learning by doing'') and accumulated knowledge (''learning by searching''); the formulation is a straightforward expansion of conventional one-factor learning curves, in which only cumulative experience is included as a factor, which aggregates the effects of accumulated knowledge and cumulative experience, among others. The responsiveness of technological progress to the two factors is quantified using learning parameters, which are estimated using empirical data. Sensitivities of the model results to the parameters are also tested. The model results also address the effect of competition between technologies and of CO 2 constraints. The results are mainly methodological; one of the most interesting is that, at least up to a point, competition between technologies-in terms of both market share and R and D support-need not lead to ''lock-in'' or ''crowding-out''. (author)

  16. Quality of assessments within reach: Review study of research and results of the quality of assessments

    NARCIS (Netherlands)

    Maassen, Nathalie Anthonia Maria; Hopster-den Otter, Dorothea; Wools, S.; Hemker, B.T.; Straetmans, G.J.J.M.; Eggen, Theodorus Johannes Hendrikus Maria

    2015-01-01

    Educational tests and assessments are important instruments to measure a student’s knowledge and skills. The question that is addressed in this review study is: “which aspects are currently considered as important to the quality of educational assessments?” Furthermore, it is explored how this

  17. [Audit as a tool to assess and promote the quality of medical records and hospital appropriateness: metodology and preliminary results].

    Science.gov (United States)

    Poscia, Andrea; Cambieri, Andrea; Tucceri, Chiara; Ricciardi, Walter; Volpe, Massimo

    2015-01-01

    In the actual economic context, with increasing health needs, efficiency and efficacy represents fundamental keyword to ensure a successful use of the resources and the best health outcomes. Together, the medical record, completely and correctly compiled, is an essential tool in the patient diagnostic and therapeutic path, but it's becoming more and more essential for the administrative reporting and legal claims. Nevertheless, even if the improvement of medical records quality and of hospital stay appropriateness represent priorities for every health organization, they could be difficult to realize. This study aims to present the methodology and the preliminary results of a training and improvement process: it was carried out from the Hospital Management of a third level Italian teaching hospital through audit cycles to actively involve their health professionals. A self assessment process of medical records quality and hospital stay appropriateness (inpatients admission and Day Hospital) was conducted through a retrospective evaluation of medical records. It started in 2012 and a random sample of 2295 medical records was examined: the quality assessment was performed using a 48-item evaluation grid modified from the Lombardy Region manual of the medical record, while the appropriateness of each days was assessed using the Italian version of Appropriateness Evaluation Protocol (AEP) - 2002ed. The overall assessment was presented through departmental audit: the audit were designed according to the indication given by the Italian and English Ministry of Health to share the methodology and the results with all the involved professionals (doctors and nurses) and to implement improvement strategies that are synthesized in this paper. Results from quality and appropriateness assessment show several deficiencies, due to 40% of minimum level of acceptability not completely satisfied and to 30% of inappropriateness between days of hospitalization. Furthermore, there are

  18. [Evaluating the effectiveness of a disease management program diabetes in the German Statutory Health Insurance: first results and methodological considerations].

    Science.gov (United States)

    Drabik, Anna; Graf, Christian; Büscher, Guido; Stock, Stephanie

    2012-01-01

    Disease management programs (DMPs) were implemented in the German Statutory Health Insurance (SHI) in a nationwide rollout in 2002. The explicit goal of the programs is to improve coordination and quality of care for the chronically ill (Sect. 137f, SGB V). To reach this goal extensive quality assurance measures in the programs are mandatory, enrolment and coordination of care rests with the primary care or DMP physician, treatment is based on evidence-based care guidelines, and patients are offered diabetes education classes to support self-management. The present study evaluates the DMP diabetes mellitus type II, a nationwide program offered by the BARMER, a German health insurance company. To minimize selection bias we formed a control group of administrative data using a propensity score matching approach. In comparison to the control group DMP participants have a significantly lower mortality rate, and their average drug and hospital costs are reduced. Enrolled patients also had a lower mean number of hospital stays and shorter hospital stays. These results indicate that the programs meet the initial goal of improving the quality of care for the chronically ill. Copyright © 2011. Published by Elsevier GmbH.

  19. Importance of methodology on (99m)technetium dimercapto-succinic acid scintigraphic image quality: imaging pilot study for RIVUR (Randomized Intervention for Children With Vesicoureteral Reflux) multicenter investigation.

    Science.gov (United States)

    Ziessman, Harvey A; Majd, Massoud

    2009-07-01

    We reviewed our experience with (99m)technetium dimercapto-succinic acid scintigraphy obtained during an imaging pilot study for a multicenter investigation (Randomized Intervention for Children With Vesicoureteral Reflux) of the effectiveness of daily antimicrobial prophylaxis for preventing recurrent urinary tract infection and renal scarring. We analyzed imaging methodology and its relation to diagnostic image quality. (99m)Technetium dimercapto-succinic acid imaging guidelines were provided to participating sites. High-resolution planar imaging with parallel hole or pinhole collimation was required. Two core reviewers evaluated all submitted images. Analysis included appropriate views, presence or lack of patient motion, adequate magnification, sufficient counts and diagnostic image quality. Inter-reader agreement was evaluated. We evaluated 70, (99m)technetium dimercapto-succinic acid studies from 14 institutions. Variability was noted in methodology and image quality. Correlation (r value) between dose administered and patient age was 0.780. For parallel hole collimator imaging good correlation was noted between activity administered and counts (r = 0.800). For pinhole imaging the correlation was poor (r = 0.110). A total of 10 studies (17%) were rejected for quality issues of motion, kidney overlap, inadequate magnification, inadequate counts and poor quality images. The submitting institution was informed and provided with recommendations for improving quality, and resubmission of another study was required. Only 4 studies (6%) were judged differently by the 2 reviewers, and the differences were minor. Methodology and image quality for (99m)technetium dimercapto-succinic acid scintigraphy varied more than expected between institutions. The most common reason for poor image quality was inadequate count acquisition with insufficient attention to the tradeoff between administered dose, length of image acquisition, start time of imaging and resulting image

  20. Quality Service Analysis and Improvement of Pharmacy Unit of XYZ Hospital Using Value Stream Analysis Methodology

    Science.gov (United States)

    Jonny; Nasution, Januar

    2013-06-01

    Value stream mapping is a tool which is needed to let the business leader of XYZ Hospital to see what is actually happening in its business process that have caused longer lead time for self-produced medicines in its pharmacy unit. This problem has triggered many complaints filed by patients. After deploying this tool, the team has come up with the fact that in processing the medicine, pharmacy unit does not have any storage and capsule packing tool and this condition has caused many wasting times in its process. Therefore, the team has proposed to the business leader to procure the required tools in order to shorten its process. This research has resulted in shortened lead time from 45 minutes to 30 minutes as required by the government through Indonesian health ministry with increased %VA (valued added activity) or Process Cycle Efficiency (PCE) from 66% to 68% (considered lean because it is upper than required 30%). This result has proved that the process effectiveness has been increase by the improvement.

  1. Quality Service Analysis and Improvement of Pharmacy Unit of XYZ Hospital Using Value Stream Analysis Methodology

    International Nuclear Information System (INIS)

    Jonny; Nasution, Januar

    2013-01-01

    Value stream mapping is a tool which is needed to let the business leader of XYZ Hospital to see what is actually happening in its business process that have caused longer lead time for self-produced medicines in its pharmacy unit. This problem has triggered many complaints filed by patients. After deploying this tool, the team has come up with the fact that in processing the medicine, pharmacy unit does not have any storage and capsule packing tool and this condition has caused many wasting times in its process. Therefore, the team has proposed to the business leader to procure the required tools in order to shorten its process. This research has resulted in shortened lead time from 45 minutes to 30 minutes as required by the government through Indonesian health ministry with increased %VA (valued added activity) or Process Cycle Efficiency (PCE) from 66% to 68% (considered lean because it is upper than required 30%). This result has proved that the process effectiveness has been increase by the improvement.

  2. A Methodological Framework for Assessing Agents, Proximate Drivers and Underlying Causes of Deforestation: Field Test Results from Southern Cameroon

    Directory of Open Access Journals (Sweden)

    Sophia Carodenuto

    2015-01-01

    Full Text Available The international debates on REDD+ and the expectations to receive results-based payments through international climate finance have triggered considerable political efforts to address deforestation and forest degradation in many potential beneficiary countries. Whether a country will receive such REDD+ payments is largely contingent on its ability to effectively address the relevant drivers, and to govern the context-dependent agents and forces responsible for forest loss or degradation. Currently, many REDD+ countries are embarking on the necessary analytical steps for their national REDD+ strategies. In this context, a comprehensive understanding of drivers and their underlying causes is a fundamental prerequisite for developing effective policy responses. We developed a methodological framework for assessing the drivers and underlying causes of deforestation and use the Fako Division in Southern Cameroon as a case study to test this approach. The steps described in this paper can be adapted to other geographical contexts, and the results of such assessments can be used to inform policy makers and other stakeholders.

  3. An Methodology for Quality Control and Draught Assessment of Room Ventilation Supply Using Laser Light Sheets

    DEFF Research Database (Denmark)

    Hviid, Christian Anker; Petersen, Steffen

    2016-01-01

    A common technique to investigate draught problems in a room is to make spot measurements of air velocity. This might identify where the draught problem is located but it does not necessarily identify the distribution and source of the problem. Usually visual inspections of the location of ventil......A common technique to investigate draught problems in a room is to make spot measurements of air velocity. This might identify where the draught problem is located but it does not necessarily identify the distribution and source of the problem. Usually visual inspections of the location...... image velocimetry software to gain overall flow pattern visualization, if not accurate readings. The latter result indicates that there could be a potential for real-time velocimetry processing by smartphones but the method in general needs further investigation and documentation....

  4. Quality of life and hormone use: new validation results of MRS scale

    Directory of Open Access Journals (Sweden)

    Heinemann Lothar AJ

    2006-05-01

    Full Text Available Abstract Background The Menopause Rating Scale is a health-related Quality of Life scale developed in the early 1990s and step-by-step validated since then. Recently the MRS scale was validated as outcomes measure for hormone therapy. The suspicion however was expressed that the data were too optimistic due to methodological problems of the study. A new study became available to check how founded this suspicion was. Method An open post-marketing study of 3282 women with pre- and post- treatment data of the self-administered version of the MRS scale was analyzed to evaluate the capacity of the scale to detect hormone treatment related effects with the MRS scale. The main results were then compared with the old study where the interview-based version of the MRS scale was used. Results The hormone-therapy related improvement of complaints relative to the baseline score was about or less than 30% in total or domain scores, whereas it exceeded 30% improvement in the old study. Similarly, the relative improvement after therapy, stratified by the degree of severity at baseline, was lower in the new than in the old study, but had the same slope. Although we cannot exclude different treatment effects with the study method used, this supports our hypothesis that the individual MRS interviews performed by the physician biased the results towards over-estimation of the treatment effects. This hypothesis is underlined by the degree of concordance of physician's assessment and patient's perception of treatment success (MRS results: Sensitivity (correct prediction of the positive assessment by the treating physician of the MRS and specificity (correct prediction of a negative assessment by the physician were lower than the results obtained with the interview-based MRS scale in the previous publication. Conclusion The study confirmed evidence for the capacity of the MRS scale to measure treatment effects on quality of life across the full range of severity of

  5. Methodology and results of the impacts of modeling electric utilities: a comparative evaluation of MEMM and REM

    International Nuclear Information System (INIS)

    1981-09-01

    This study compares two models of the US electric utility industry including the EIA's electric utility submodel in the Midterm Energy Market Model (MEMM), and the Baughman-Joskow Regionalized Electricity Model (REM). The method of comparison emphasizes reconciliation of differences in data common to both models, and the performance of simulation experiments to evaluate the empirical significance of certain structural differences in the models. The major research goal was to contrast and compare the effects of alternative modeling structures and data assumptions on model results; and, particularly to considered each model's approach to the impacts of generation technology and fuel use choices on electric utilities. The methodology used was to run the REM model first without and, then, with a representation of the Power Plant and Industrial Fuel Act of 1978, assuming medium supply and demand curves and varying fuel prices. The models and data structures of the two models are described. The original 1978 data used in MEMM and REM are analyzed and compared. The computations and effects of different assumptions on fuel use decisions are discussed. The adjusted REM data required for the experiments are presented. Simulation results of the two models are compared. These results represent projections for 1985, 1990, and 1995 of: US power generation by plant type; amounts of each type of fuel used for power generation; average electricity prices; and the effects of additional or fewer nuclear and coal-fired plants. A significant result is that the REM model exhibits about 7 times as much gas and oil consumption in 1995 as the MEMM model. Continuing simulation experiments on MEMM are recommended to determine whether the input data to MEMM are reasonable and properly adjusted

  6. [Statistical (Poisson) motor unit number estimation. Methodological aspects and normal results in the extensor digitorum brevis muscle of healthy subjects].

    Science.gov (United States)

    Murga Oporto, L; Menéndez-de León, C; Bauzano Poley, E; Núñez-Castaín, M J

    Among the differents techniques for motor unit number estimation (MUNE) there is the statistical one (Poisson), in which the activation of motor units is carried out by electrical stimulation and the estimation performed by means of a statistical analysis based on the Poisson s distribution. The study was undertaken in order to realize an approximation to the MUNE Poisson technique showing a coprehensible view of its methodology and also to obtain normal results in the extensor digitorum brevis muscle (EDB) from a healthy population. One hundred fourteen normal volunteers with age ranging from 10 to 88 years were studied using the MUNE software contained in a Viking IV system. The normal subjects were divided into two age groups (10 59 and 60 88 years). The EDB MUNE from all them was 184 49. Both, the MUNE and the amplitude of the compound muscle action potential (CMAP) were significantly lower in the older age group (page than CMAP amplitude ( 0.5002 and 0.4142, respectively pphisiology of the motor unit. The value of MUNE correlates better with the neuromuscular aging process than CMAP amplitude does.

  7. [Risk adjusted assessment of quality of perinatal centers - results of perinatal/neonatal quality surveillance in Saxonia].

    Science.gov (United States)

    Koch, R; Gmyrek, D; Vogtmann, Ch

    2005-12-01

    The weak point of the country-wide perinatal/neonatal quality surveillance as a tool for evaluation of achievements of a distinct clinic, is the ignorance of interhospital differences in the case-mix of patients. Therefore, that approach can not result in a reliable bench marking. To adjust the results of quality assessment of different hospitals according to their risk profile of patients by multivariate analysis. The perinatal/neonatal data base of 12.783 newborns of the saxonian quality surveillance from 1998 to 2000 was analyzed. 4 relevant quality indicators of newborn outcome -- a) severe intraventricular hemorrhage in preterm infants 2500 g and d) hypoxic-ischemic encephalopathy -- were targeted to find out specific risk predictors by considering 26 risk factors. A logistic regression model was used to develop the risk predictors. Risk predictors for the 4 quality indicators could be described by 3 - 9 out of 26 analyzed risk factors. The AUC (ROC)-values for these quality indicators were 82, 89, 89 and 89 %, what signifies their reliability. Using the new specific predictors for calculation the risk adjusted incidence rates of quality indicator yielded in some remarkable changes. The apparent differences in the outcome criteria of analyzed hospitals were found to be much less pronounced. The application of the proposed method for risk adjustment of quality indicators makes it possible to perform a more objective comparison of neonatal outcome criteria between different hospitals or regions.

  8. Consumer perception of the quality of beef resulting from various fattening regimes

    DEFF Research Database (Denmark)

    Brunsø, Karen; Bredahl, Lone; Grunert, Klaus G.

    2005-01-01

    with beef will be presented. Consumers form expectations about the eating quality of meat at the point of purchase, based on prior experience and information available in the shopping environment, while the eating quality is experienced at home during and after meal preparation. Results show that consumers......The evaluation of meat quality and safety is not a straightforward task for consumers. In this article, the Total Food Quality Model will be introduced as a framework for understanding how consumers perceive meat quality, and results from a Danish study of consumer perception and experience...

  9. Postgraduate Education in Quality Improvement Methods: Initial Results of the Fellows' Applied Quality Training (FAQT) Curriculum.

    Science.gov (United States)

    Winchester, David E; Burkart, Thomas A; Choi, Calvin Y; McKillop, Matthew S; Beyth, Rebecca J; Dahm, Phillipp

    2016-06-01

    Training in quality improvement (QI) is a pillar of the next accreditation system of the Accreditation Committee on Graduate Medical Education and a growing expectation of physicians for maintenance of certification. Despite this, many postgraduate medical trainees are not receiving training in QI methods. We created the Fellows Applied Quality Training (FAQT) curriculum for cardiology fellows using both didactic and applied components with the goal of increasing confidence to participate in future QI projects. Fellows completed didactic training from the Institute for Healthcare Improvement's Open School and then designed and completed a project to improve quality of care or patient safety. Self-assessments were completed by the fellows before, during, and after the first year of the curriculum. The primary outcome for our curriculum was the median score reported by the fellows regarding their self-confidence to complete QI activities. Self-assessments were completed by 23 fellows. The majority of fellows (15 of 23, 65.2%) reported no prior formal QI training. Median score on baseline self-assessment was 3.0 (range, 1.85-4), which was significantly increased to 3.27 (range, 2.23-4; P = 0.004) on the final assessment. The distribution of scores reported by the fellows indicates that 30% were slightly confident at conducting QI activities on their own, which was reduced to 5% after completing the FAQT curriculum. An interim assessment was conducted after the fellows completed didactic training only; median scores were not different from the baseline (mean, 3.0; P = 0.51). After completion of the FAQT, cardiology fellows reported higher self-confidence to complete QI activities. The increase in self-confidence seemed to be limited to the applied component of the curriculum, with no significant change after the didactic component.

  10. The methodological quality of guidelines for hospital-acquired pneumonia and ventilator-associated pneumonia: A systematic review.

    Science.gov (United States)

    Ambaras Khan, R; Aziz, Z

    2018-05-02

    Clinical practice guidelines serve as a framework for physicians to make decisions and to support best practice for optimizing patient care. However, if the guidelines do not address all the important components of optimal care sufficiently, the quality and validity of the guidelines can be reduced. The objectives of this study were to systematically review current guidelines for hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP), evaluate their methodological quality and highlight the similarities and differences in their recommendations for empirical antibiotic and antibiotic de-escalation strategies. This review is reported in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) statement. Electronic databases including MEDLINE, CINAHL, PubMed and EMBASE were searched up to September 2017 for relevant guidelines. Other databases such as NICE, Scottish Intercollegiate Guidelines Network (SIGN) and the websites of professional societies were also searched for relevant guidelines. The quality and reporting of included guidelines were assessed using the Appraisal of Guidelines for Research and Evaluation II (AGREE-II) instrument. Six guidelines were eligible for inclusion in our review. Among 6 domains of AGREE-II, "clarity of presentation" scored the highest (80.6%), whereas "applicability" scored the lowest (11.8%). All the guidelines supported the antibiotic de-escalation strategy, whereas the majority of the guidelines (5 of 6) recommended that empirical antibiotic therapy should be implemented in accordance with local microbiological data. All the guidelines suggested that for early-onset HAP/VAP, therapy should start with a narrow spectrum empirical antibiotic such as penicillin or cephalosporins, whereas for late-onset HAP/VAP, the guidelines recommended the use of a broader spectrum empirical antibiotic such as the penicillin extended spectrum carbapenems and glycopeptides. Expert guidelines

  11. Analysis of environmental contamination resulting from catastrophic incidents: part 2. Building laboratory capability by selecting and developing analytical methodologies.

    Science.gov (United States)

    Magnuson, Matthew; Campisano, Romy; Griggs, John; Fitz-James, Schatzi; Hall, Kathy; Mapp, Latisha; Mullins, Marissa; Nichols, Tonya; Shah, Sanjiv; Silvestri, Erin; Smith, Terry; Willison, Stuart; Ernst, Hiba

    2014-11-01

    Catastrophic incidents can generate a large number of samples of analytically diverse types, including forensic, clinical, environmental, food, and others. Environmental samples include water, wastewater, soil, air, urban building and infrastructure materials, and surface residue. Such samples may arise not only from contamination from the incident but also from the multitude of activities surrounding the response to the incident, including decontamination. This document summarizes a range of activities to help build laboratory capability in preparation for sample analysis following a catastrophic incident, including selection and development of fit-for-purpose analytical methods for chemical, biological, and radiological contaminants. Fit-for-purpose methods are those which have been selected to meet project specific data quality objectives. For example, methods could be fit for screening contamination in the early phases of investigation of contamination incidents because they are rapid and easily implemented, but those same methods may not be fit for the purpose of remediating the environment to acceptable levels when a more sensitive method is required. While the exact data quality objectives defining fitness-for-purpose can vary with each incident, a governing principle of the method selection and development process for environmental remediation and recovery is based on achieving high throughput while maintaining high quality analytical results. This paper illustrates the result of applying this principle, in the form of a compendium of analytical methods for contaminants of interest. The compendium is based on experience with actual incidents, where appropriate and available. This paper also discusses efforts aimed at adaptation of existing methods to increase fitness-for-purpose and development of innovative methods when necessary. The contaminants of interest are primarily those potentially released through catastrophes resulting from malicious activity

  12. [10 years of external quality assurance in dialysis in Germany: Results and future prospects].

    Science.gov (United States)

    Büchtemann, Dorothea; Meinhold, Stefan; Follert, Peter

    2017-10-01

    In 2006, the Federal Joint Committee introduced a quality assurance programme for ambulatory dialysis treatment in Germany. Regarding the impact of chronic dialysis treatment on the quality of life of patients and on health care costs, quality assurance in dialysis is considered highly relevant. The directive on Quality Assurance in Dialysis (QSD-RL) established an external quality assurance programme on the basis of the assessment of certain quality parameters combined with an internal quality management system based on benchmarking parameters in all dialysis practices and centres. Data on quality parameters are collected and analysed quarterly. Regional associations of statutory health insurance physicians take responsibility for quality improvement measures and sanctions. This article aims to provide an overview of the development of quality parameters from 2008 to 2015. We analysed the summarised annual quality reports published on the website of the Federal Joint Committee between 2009 and 2016. We present results on the so-called core quality parameters duration and frequency of dialysis sessions (both for haemodialysis patients), wKt/V for peritoneal dialysis patients, and percentage of haemodialysis patients with central venous catheters which has only been measured since 2014. In 2015, 92,000 patients received outpatient dialysis. Between 2008 and 2015, the results for the core quality parameters duration and frequency of haemodialysis improved while the results for wKt/V seemingly show an unfavourable trend. The percentage of patients with central venous catheters appears to be quite high, and thus indicates that there is potential for quality improvement. For the future, the Federal Joint Committee has resolved to merge the quality assurance programmes in dialysis and in kidney transplantation into a newly designed programme that has the potential to follow patients through all stages and kinds of renal replacement therapy and to focus on further aspects

  13. [Regional differences of ADHD diagnosis rates in health insurance data from 2005 to 2015 : Methodological considerations and results].

    Science.gov (United States)

    Grobe, Thomas G

    2017-12-01

    Attention deficit hyperactivity disorders (ADHD) are among the most common mental disorders in children and adolescents. For a number of years there has been evidence of regional differences in Germany. This article provides current results on the frequency of diagnosis and treatment and also discusses methodological aspects. The analysis is based on routine data of a statutory health insurance company including annual diagnoses and drug prescriptions from 2005 to 2015 of at least 1.34 million children and adolescents between 0 and 19 years of age. Small-area results of ADHD diagnosis rates and methylphenidate prescriptions are presented with a standardized differentiation according to 413 districts pursuant to territorial status from the end of 2008. From 2005 to 2014, ADHD diagnoses were documented for an increasing proportion of 0 to 19-year-olds in Germany. In 2015 the proportion was 4.2%; boys aged 10 were affected most frequently with a proportion of 11.1%. Regional diagnosis rates vary considerably. Two counties showed diagnosis and prescription rates that were more than twice as high as regionally expected for all years in question; other districts showed rates that were continually lower than expected by at least a third. Analyses on the level of administratively defined districts have some advantages but alternative regional structuring would be desirable due to very heterogeneous population figures. Regarding ADHD diagnoses and documented methylphenidate prescriptions on an outpatient basis, significant regional differences in Germany were detected, for which plausible medical justifications do not yet exist. Specialist discussions seem urgently needed.

  14. Optimization of edible coating formulations for improving postharvest quality and shelf life of pear fruit using response surface methodology.

    Science.gov (United States)

    Nandane, A S; Dave, Rudri K; Rao, T V Ramana

    2017-01-01

    The effect of composite edible films containing soy protein isolate (SPI) in combination with additives like hydroxypropyl methylcellulose (HPMC) and olive oil on 'Babughosha' pear ( Pyrus communis L.) stored at ambient temperature (28 ± 5 °C and 60 ± 10% RH) was evaluated using Response surface methodology (RSM). A total of 30 edible coating formulations comprising of SPI (2-6%, w/v), olive oil (0.7-1.1%, v/v), HPMC (0.1-0.5%, w/v) and potassium sorbate (0-0.4% w/v) were evaluated for optimizing the most suitable combination. Quality parameters like weight loss%, TSS, pH and titrable acidity of the stored pears were selected as response variables for optimization. The optimization procedure was carried out using RSM. It was observed that the response variables were mainly effected by concentration of SPI and olive oil in the formulation. Edible coating comprising of SPI 5%, HPMC 0.40%, olive oil 1% and potassium sorbate 0.22% was found to be most suitable combination for pear fruit with predicted values of response variables indicated as weight loss% 3.50, pH 3.41, TSS 11.13 and TA% 0.513.

  15. An investigation of laser cutting quality of 22MnB5 ultra high strength steel using response surface methodology

    Science.gov (United States)

    Tahir, Abdul Fattah Mohd; Aqida, Syarifah Nur

    2017-07-01

    In hot press forming, changes of mechanical properties in boron steel blanks have been a setback in trimming the final shape components. This paper presents investigation of kerf width and heat affected zone (HAZ) of ultra high strength 22MnB5 steel cutting. Sample cutting was conducted using a 4 kW Carbon Dioxide (CO2) laser machine with 10.6 μm wavelength with the laser spot size of 0.2 mm. A response surface methodology (RSM) using three level Box-Behnken design of experiment was developed with three factors of peak power, cutting speed and duty cycle. The parameters were optimised for minimum kerf width and HAZ formation. Optical evaluation using MITUTOYO TM 505 were conducted to measure the kerf width and HAZ region. From the findings, laser duty cycle was crucial to determine cutting quality of ultra-high strength steel; followed by cutting speed and laser power. Meanwhile, low power intensity with continuous wave contributes the narrowest kerf width formation and least HAZ region.

  16. Investigating the association between medication adherence and health-related quality of life in COPD : Methodological challenges when using a proxy measure of adherence

    NARCIS (Netherlands)

    Boland, Melinde R. S.; van Boven, Job F. M.; Kruis, Annemarije L.; Chavannes, Niels H.; van der Molen, Thys; Goossens, Lucas M. A.; Rutten-van Molken, Maureen P. M. H.

    Background: The association between non-adherence to medication and health-related quality-of-life (HRQoL) in Chronic Obstructive Pulmonary Disease (COPD) remains poorly understood. Different ways to deal with methodological challenges to estimate this association have probably contributed to

  17. A national strategy for identification, prioritisation and management of pollution from abandoned non-coal mine sites in England and Wales. I. Methodology development and initial results.

    Science.gov (United States)

    Mayes, W M; Johnston, D; Potter, H A B; Jarvis, A P

    2009-10-15

    In regions affected by historic non-coal (principally metal) mining activity, government agencies are often faced with the challenge of deploying limited remedial resources at abandoned mine sites to achieve maximum improvements in the chemical and ecological quality of impacted ground and surface waters. As such, strategies for the defensible allocation of public funds require comprehensive and systematic frameworks by which to identify and prioritise polluting sites for remediation. This paper describes the development and initial findings of such a national initiative in England and Wales which allies catchment-scale environmental impact assessments using existing public archive data, with recognition of the uncertainty in impact appraisals arising from disparities in data availability between sites and regions. The methodology identifies polluting sites and takes account not only of the chemical and ecological impacts of mine water discharges on receiving watercourses, but also of socio-economic factors such as conservation and heritage concerns, which can both impede or complement efforts to remediate mine sites. Using a Geographic Information System database and a suite of spatial analyses employing Boolean operators, both the extent of the pollution problem from abandoned non-coal mines in England and Wales (6% of 7815 surface water bodies are affected nationally) and the insight that can be gleaned from systematic analyses of existing archive data are highlighted. The results of the nationwide survey can be used as a dynamic database to inform future remedial planning, in terms of prioritising impacted river basins and abandoned non-coal mine sites themselves for either remediation or future monitoring efforts. As the assessment framework is built upon existing water quality and ecological data and mine site/geological data, there is considerable scope for the approach to be applied elsewhere where the legacy of historic mining persists through the

  18. Analysis of information quality attribute for SME towards adoption of research result

    Science.gov (United States)

    Febriani, E.; Dewobroto, W. S.; Anggraini, R. D.

    2017-12-01

    Small and Medium Enterprises (SME) holds significant role in fostering Indonesian economy. However, the research that is supposed to support the development of SMEs business has not yet fully adopted or utilized. Information attributes may be used as the benchmark to find the intention of SMEs from a research result and develop the strategy of quality information for all organizations both SMEs and the researcher. Therefore, because of the importance of information quality attribute required by SMEs, the research aims to analyses the information quality required by SMEs to clarify the information quality into the dimension of information quality. The research was started by distributing online questionnaire to SMEs. The questionnaire result showed that the content dimension is the most aspect required by SMEs, followed by time and form dimension, respectively. Quality information attribute required by SMEs from a research is that the result may be applied to the business.

  19. Integrating cost information with health management support system: an enhanced methodology to assess health care quality drivers.

    Science.gov (United States)

    Kohli, R; Tan, J K; Piontek, F A; Ziege, D E; Groot, H

    1999-08-01

    Changes in health care delivery, reimbursement schemes, and organizational structure have required health organizations to manage the costs of providing patient care while maintaining high levels of clinical and patient satisfaction outcomes. Today, cost information, clinical outcomes, and patient satisfaction results must become more fully integrated if strategic competitiveness and benefits are to be realized in health management decision making, especially in multi-entity organizational settings. Unfortunately, traditional administrative and financial systems are not well equipped to cater to such information needs. This article presents a framework for the acquisition, generation, analysis, and reporting of cost information with clinical outcomes and patient satisfaction in the context of evolving health management and decision-support system technology. More specifically, the article focuses on an enhanced costing methodology for determining and producing improved, integrated cost-outcomes information. Implementation issues and areas for future research in cost-information management and decision-support domains are also discussed.

  20. [Evaluation of the methodological quality of the Rémic (microbiology guidelines - bacteriology and mycology) of the Société française de microbiologie].

    Science.gov (United States)

    Fonfrède, Michèle; Couaillac, Jean Paul; Augereau, Christine; De Moüy, Danny; Lepargneur, Jean Pierre; Szymanowicz, Anton; Watine, Joseph

    2011-01-01

    We have evaluated the methodological quality of the Rémic (microbiology guidelines - bacteriology and mycology) of the Société française de microbiologie (edition2007), using to AGREE criteria, which are consensual at an international level, in particular at the the World Health Organisation (WHO) and at the European Union. The methodological quality of the Rémic appears to be sub-optimal. These shortcomings in quality are mainly observed in AGREE domain n° 5 (applicability), in AGREE item n° 5 (patients' opinions were not considered), and in AGREE item n° 23 (conflicts of interest were not declared). The users of the Rémic must be aware of these few methodological shortcomings in order for them to be careful before they put its recommendation in practice. In conclusion, we advise the editors of the Rémic to insert at least a methodological chapter in their next edition.

  1. Preliminary results of the national program of audit of quality in radiotherapy services in the Republic of Cuba

    International Nuclear Information System (INIS)

    Dominguez Hung, Lourdes; Larrinaga Cortina, Eduardo F.; Morales Lopez, Jorge L.; Garcia Yip, Fernando; Campa Menendez, Raudel

    2001-01-01

    The current state of the radiotherapy in Cuba has allowed to pass to a superior stage, the establishment of a National Quality Audit Program (PNAC). The National Control Center for Medical Devices as national regulator entity for the control and supervision of the medical devices of the National Health System is the responsible for it implementation. This paper presents the preliminary results of the execution of the PNAC in teletherapy services with isotopic units of 60 Co. The audits were carried out according to the methodology settled down in the normalized procedure of operation of the PNAC. The physical aspects related with the treatment were audit, such as: the installation and unit's security, treatment unit's mechanical and dosimetric aspects and organizational aspects of the institution quality assurance program. Also were carried out, in the clinical aspect, verifications of cases type planned by the qualified personnel of the service. The results corresponding to the determination of the reference dose for each institution were compared with those obtained in a postal audit with the International Atomic Energy Agency. These first audits allowed to evaluate the performance of the institution's program of quality assurance and a feedback for the setting about to the PNAC. (author)

  2. Model development for mechanical properties and weld quality class of friction stir welding using multi-objective Taguchi method and response surface methodology

    International Nuclear Information System (INIS)

    Mohamed, Mohamed Ackiel; Manurung, Yupiter HP; Berhan, Mohamed Nor

    2015-01-01

    This study presents the effect of the governing parameters in friction stir welding (FSW) on the mechanical properties and weld quality of a 6mm thick 6061 T651 Aluminum alloy butt joint. The main FSW parameters, the rotational and traverse speed were optimized based on multiple mechanical properties and quality features, which focus on the tensile strength, hardness and the weld quality class using the multi-objective Taguchi method (MTM). Multi signal to noise ratio (MSNR) was employed to determine the optimum welding parameters for MTM while further analysis concerning the significant level determination was accomplished via the well-established analysis of variance (ANOVA). Furthermore, the first order model for predicting the mechanical properties and weld quality class is derived by applying response surface methodology (RSM). Based on the experimental confirmation test, the proposed method can effectively estimate the mechanical properties and weld quality class which can be used to enhance the welding performance in FSW or other applications.

  3. Model development for mechanical properties and weld quality class of friction stir welding using multi-objective Taguchi method and response surface methodology

    Energy Technology Data Exchange (ETDEWEB)

    Mohamed, Mohamed Ackiel [University Kuala Lumpur Malaysia France Institute, Bandar Baru Bangi (Malaysia); Manurung, Yupiter HP; Berhan, Mohamed Nor [Universiti Teknologi MARA, Shah Alam (Malaysia)

    2015-06-15

    This study presents the effect of the governing parameters in friction stir welding (FSW) on the mechanical properties and weld quality of a 6mm thick 6061 T651 Aluminum alloy butt joint. The main FSW parameters, the rotational and traverse speed were optimized based on multiple mechanical properties and quality features, which focus on the tensile strength, hardness and the weld quality class using the multi-objective Taguchi method (MTM). Multi signal to noise ratio (MSNR) was employed to determine the optimum welding parameters for MTM while further analysis concerning the significant level determination was accomplished via the well-established analysis of variance (ANOVA). Furthermore, the first order model for predicting the mechanical properties and weld quality class is derived by applying response surface methodology (RSM). Based on the experimental confirmation test, the proposed method can effectively estimate the mechanical properties and weld quality class which can be used to enhance the welding performance in FSW or other applications.

  4. Preliminary comparative assessment of PM10 hourly measurement results from new monitoring stations type using stochastic and exploratory methodology and models

    Science.gov (United States)

    Czechowski, Piotr Oskar; Owczarek, Tomasz; Badyda, Artur; Majewski, Grzegorz; Rogulski, Mariusz; Ogrodnik, Paweł

    2018-01-01

    The paper presents selected preliminary stage key issues proposed extended equivalence measurement results assessment for new portable devices - the comparability PM10 concentration results hourly series with reference station measurement results with statistical methods. In article presented new portable meters technical aspects. The emphasis was placed on the comparability the results using the stochastic and exploratory methods methodology concept. The concept is based on notice that results series simple comparability in the time domain is insufficient. The comparison of regularity should be done in three complementary fields of statistical modeling: time, frequency and space. The proposal is based on model's results of five annual series measurement results new mobile devices and WIOS (Provincial Environmental Protection Inspectorate) reference station located in Nowy Sacz city. The obtained results indicate both the comparison methodology completeness and the high correspondence obtained new measurements results devices with reference.

  5. Prevalence of cluster headache in the Republic of Georgia: results of a population-based study and methodological considerations

    DEFF Research Database (Denmark)

    Katsarava, Z; Dzagnidze, A; Kukava, M

    2009-01-01

    We present a study of the general-population prevalence of cluster headache in the Republic of Georgia and discuss the advantages and challenges of different methodological approaches. In a community-based survey, specially trained medical residents visited 500 adjacent households in the capital...... with possible cluster headache, who were then personally interviewed by one of two headache-experienced neurologists. Cluster headache was confirmed in one subject. The prevalence of cluster headache was therefore estimated to be 87/100,000 (95% confidence interval

  6. Higher quality of molecular testing, an unfulfilled priority: Results from external quality assessment for KRAS mutation testing in colorectal cancer.

    Science.gov (United States)

    Tembuyser, Lien; Ligtenberg, Marjolijn J L; Normanno, Nicola; Delen, Sofie; van Krieken, J Han; Dequeker, Elisabeth M C

    2014-05-01

    Precision medicine is now a key element in clinical oncology. RAS mutational status is a crucial predictor of responsiveness to anti-epidermal growth factor receptor agents in metastatic colorectal cancer. In an effort to guarantee high-quality testing services in molecular pathology, the European Society of Pathology has been organizing an annual KRAS external quality assessment program since 2009. In 2012, 10 formalin-fixed, paraffin-embedded samples, of which 8 from invasive metastatic colorectal cancer tissue and 2 artificial samples of cell line material, were sent to more than 100 laboratories from 26 countries with a request for routine KRAS testing. Both genotyping and clinical reports were assessed independently. Twenty-seven percent of the participants genotyped at least 1 of 10 samples incorrectly. In total, less than 5% of the distributed specimens were genotyped incorrectly. Genotyping errors consisted of false negatives, false positives, and incorrectly genotyped mutations. Twenty percent of the laboratories reported a technical error for one or more samples. A review of the written reports showed that several essential elements were missing, most notably a clinical interpretation of the test result, the method sensitivity, and the use of a reference sequence. External quality assessment serves as a valuable educational tool in assessing and improving molecular testing quality and is an important asset for monitoring quality assurance upon incorporation of new biomarkers in diagnostic services. Copyright © 2014 American Society for Investigative Pathology and the Association for Molecular Pathology. Published by Elsevier Inc. All rights reserved.

  7. How Do Quality Practices Affect the Results?: The Experience of Thalassotherapy Centres in Spain

    Directory of Open Access Journals (Sweden)

    José Álvarez-García

    2017-04-01

    Full Text Available Most thalassotherapy centres in Spain do not have any quality certification but they are carrying out several actions of quality management in an attempt to obtain better results. Consequently, the aim of this research is to study if the implementation of quality practices on thalassotherapy centres has the same impact on companies’ results as on the results of those companies that got the quality certifications. In addition, the relationships between different factors considered are going to be studied. Our sample is composed of Spanish thalassotherapy centres, and the statistical technique used is based on structural equation modelling, in particular partial least squares (PLS regression. The data were provided by the answers given by 31 managers (70.45% of the selected sample to a structured questionnaire based on previous research and statistically validated. The results of this research allow us to conclude that these kinds of organizations have implemented informal practices to improve the quality of the service in terms of leadership, personnel management, alliances, and resources and show that the practices that have been carried out by these centres to enhance the quality of the service have an impact on companies’ results. Managers of these kinds of establishments that want to improve customer results should focus their efforts on continuous improvement, whereas, if they are pursuing enhancement of other results, their efforts should be focused on process management.

  8. New Brunswick air quality monitoring results for the year 2007 : executive summary

    International Nuclear Information System (INIS)

    2009-01-01

    Air quality has been monitored in New Brunswick since the 1960s. This report summarized air quality results for general public information, with emphasis on air quality assessment in relation to existing air quality standards and objectives. Long-term trend data were also presented for representative sites. Air contaminants currently covered by provincial objectives were measured at 59 sites across the province during 2007. Acid rain was measured at 13 additional sites. Some locations were monitored for volatile organic compounds and mercury in air. Quality assurance procedures used in the provincial air quality system were also described. The report revealed that there were no exceedances of New Brunswick air quality objectives for nitrogen dioxide or carbon monoxide at any of the provincial monitoring sites in 2007. In many instances, exceedances for ozone, total reduced sulphur, fine particulate matter and total volatile organic compound concentrations were lower in 2007 than in 2006. Air quality trends indicate that since the late 1970s and 1980s, air quality has improved for all pollutants currently being measured, with the possible exception of ground level ozone. Annual average levels of sulphur dioxide have decreased significantly over the past 15-20 years. The long term levels of carbon monoxide and nitrogen dioxide have also decreased. Acid deposition has declined since the early 1990s, but its effects continue to be of concern in the province. In 2007, sulphate in precipitation was moderately lower than in 2006.

  9. Improving quality of reproductive health care in Senegal through formative supervision: results from four districts

    Directory of Open Access Journals (Sweden)

    Moreira Philippe

    2007-11-01

    Full Text Available Abstract Background In Senegal, traditional supervision often focuses more on collection of service statistics than on evaluation of service quality. This approach yields limited information on quality of care and does little to improve providers' competence. In response to this challenge, Management Sciences for Health (MSH has implemented a program of formative supervision. This multifaceted, problem-solving approach collects data on quality of care, improves technical competence, and engages the community in improving reproductive health care. Methods This study evaluated changes in service quality and community involvement after two rounds of supervision in 45 health facilities in four districts of Senegal. We used checklists to assess quality in four areas of service delivery: infrastructure, staff and services management, record-keeping, and technical competence. We also measured community involvement in improving service quality using the completion rates of action plans. Results The most notable improvement across regions was in infection prevention. Management of staff, services, and logistics also consistently improved across the four districts. Record-keeping skills showed variable but lower improvement by region. The completion rates of action plans suggest that communities are engaged in improving service quality in all four districts. Conclusion Formative supervision can improve the quality of reproductive health services, especially in areas where there is on-site skill building and refresher training. This approach can also mobilize communities to participate in improving service quality.

  10. Safety Assessment for Decommissioning of Nuclear Facilities - From Methodology to the Use of Results in Decision Making

    International Nuclear Information System (INIS)

    Batandjieva, B.; Ferch, R.; Joubert, A.; Kaulard, J.; Manson, P.; Percival, K.; Thierfeldt, St.

    2008-01-01

    The safety assessment of operational facilities in the nuclear industry is well understood and methodologies have been developed and refined over several decades. Similarly safety assessment methodologies for near surface disposal facilities have been harmonized internationally during the last few years. There is however relatively less widespread and documented experience of safety assessment for decommissioning among Member States of the International Atomic Energy Agency (IAEA) and consequently there is less commonalty of approaches internationally. The importance of safety during decommissioning was further emphasized at the first review meeting of the Joint Convention on the Safety of Spent Fuel Management and on the Safety of Radioactive Waste Management, and the Berlin Conference 'Safe Decommissioning for Nuclear Activities' (14-18 October 2002). As a consequence during its June 2004 meeting the IAEA Board of Governors approved an Action Plan on Decommissioning of nuclear Facilities that requested the Secretariat to 'establish a forum for the sharing and exchange of national information and experience on the application of safety assessment in the context of decommissioning and provide a means to convey this information to other interested parties, also drawing on the work of other international organizations in this area'. In response the IAEA launched the International Project Evaluation and Demonstration of Safety during Decommissioning of Nuclear Facilities (DeSa) in November 2004 with the following objectives: - To develop a harmonized approach to safety assessment and define the elements of safety assessment for decommissioning; - To investigate the practical applicability of the methodology and performance of safety assessments for the decommissioning of various types of facilities through a selected number of test cases; - To investigate approaches for review of safety assessments for decommissioning activities and the development of a regulatory

  11. Quality-productivity decision making when turning of Inconel 718 aerospace alloy: A response surface methodology approach

    Directory of Open Access Journals (Sweden)

    Hamid Tebassi

    2017-06-01

    Full Text Available Inconel 718 is among difficult to machine materials because of its abrasiveness and high strength even at high temperature. This alloy is mainly used in aircraft and aerospace industries. Therefore, it is very important to reveal and evaluate cutting tools behavior during machining of this kind of alloy. The experimental study presented in this research work has been carried out in order to elucidate surface roughness and productivity mathematical models during turning of Inconel 718 superalloy (35 HRC with SiC Whisker ceramic tool at various cutting parameters (depth of cut, feed rate, cutting speed and radius nose. A small central composite design (SCCD including 16 basics runs replicated three times (48 runs, was adopted and graphically evaluated using Fraction of design space (FDS graph, completed by a statistical analysis of variance (ANOVA. Mathematical models for surface roughness and productivity were developed and normality was improved using the Box-Cox transformation. Results show that surface roughness criterion Ra was mainly influenced by cutting speed, radius nose and feed rate, and that the depth of cut had major effect on productivity. Finally, ranges of optimized cutting conditions were proposed for serial industrial production. Industrial benefit was illustrated in terms of high surface quality accompanied with high productivity. Indeed, results show that the use of optimal cutting condition had an industrial benefit to 46.9 % as an improvement in surface quality Ra and 160.54 % in productivity MRR.

  12. An integrated quality function deployment and capital budgeting methodology for occupational safety and health as a systems thinking approach: the case of the construction industry.

    Science.gov (United States)

    Bas, Esra

    2014-07-01

    In this paper, an integrated methodology for Quality Function Deployment (QFD) and a 0-1 knapsack model is proposed for occupational safety and health as a systems thinking approach. The House of Quality (HoQ) in QFD methodology is a systematic tool to consider the inter-relationships between two factors. In this paper, three HoQs are used to consider the interrelationships between tasks and hazards, hazards and events, and events and preventive/protective measures. The final priority weights of events are defined by considering their project-specific preliminary weights, probability of occurrence, and effects on the victim and the company. The priority weights of the preventive/protective measures obtained in the last HoQ are fed into a 0-1 knapsack model for the investment decision. Then, the selected preventive/protective measures can be adapted to the task design. The proposed step-by-step methodology can be applied to any stage of a project to design the workplace for occupational safety and health, and continuous improvement for safety is endorsed by the closed loop characteristic of the integrated methodology. Copyright © 2013 Elsevier Ltd. All rights reserved.

  13. Systematic reviews and meta-analyses on psoriasis: role of funding sources, conflict of interest and bibliometric indices as predictors of methodological quality.

    Science.gov (United States)

    Gómez-García, F; Ruano, J; Aguilar-Luque, M; Gay-Mimbrera, J; Maestre-Lopez, B; Sanz-Cabanillas, J L; Carmona-Fernández, P J; González-Padilla, M; Vélez García-Nieto, A; Isla-Tejera, B

    2017-06-01

    The quality of systematic reviews and meta-analyses on psoriasis, a chronic inflammatory skin disease that severely impairs quality of life and is associated with high costs, remains unknown. To assess the methodological quality of systematic reviews published on psoriasis. After a comprehensive search in MEDLINE, Embase and the Cochrane Database (PROSPERO: CDR42016041611), the quality of studies was assessed by two raters using the Assessment of Multiple Systematic Reviews (AMSTAR) tool. Article metadata and journal-related bibliometric indices were also obtained. Systematic reviews were classified as low (0-4), moderate (5-8) or high (9-11) quality. A prediction model for methodological quality was fitted using principal component and multivariate ordinal logistic regression analyses. We classified 220 studies as high (17·2%), moderate (55·0%) or low (27·8%) quality. Lower compliance rates were found for AMSTAR question (Q)5 (list of studies provided, 11·4%), Q10 (publication bias assessed, 27·7%), Q4 (status of publication included, 39·5%) and Q1 (a priori design provided, 40·9%). Factors such as meta-analysis inclusion [odds ratio (OR) 6·22; 95% confidence interval (CI) 2·78-14·86], funding by academic institutions (OR 2·90, 95% CI 1·11-7·89), Article Influence score (OR 2·14, 95% CI 1·05-6·67), 5-year impact factor (OR 1·34, 95% CI 1·02-1·40) and article page count (OR 1·08, 95% CI 1·02-1·15) significantly predicted higher quality. A high number of authors with a conflict of interest (OR 0·90, 95% CI 0·82-0·99) was significantly associated with lower quality. The methodological quality of systematic reviews published about psoriasis remains suboptimal. The type of funding sources and author conflicts may compromise study quality, increasing the risk of bias. © 2017 British Association of Dermatologists.

  14. Impact of methodological choices on findings from pharmacoepidemiological studies: Final results of the IMI-protect (pharmacoepidemiological research on outcomes of therapeutics by a European consortium) project

    NARCIS (Netherlands)

    Klungel, Olaf; De Groot, Mark; Gardarsdottir, Helga; Brauer, Ruth; Grimaldi-Bensouda, Lamiae; Kurz, Xavier; Gasse, Christiane; Reynolds, Robert

    2014-01-01

    Background: Pharmacoepidemiological (PE) research should provide consistent, reliable and reproducible results to contribute to the benefit-risk assessment of medicines. IMI-PROTECT aims to identify sources of methodological variations in PE studies using a common protocol and analysis plan across

  15. Consequences of using different soil texture determination methodologies for soil physical quality and unsaturated zone time lag estimates.

    Science.gov (United States)

    Fenton, O; Vero, S; Ibrahim, T G; Murphy, P N C; Sherriff, S C; Ó hUallacháin, D

    2015-11-01

    Elucidation of when the loss of pollutants, below the rooting zone in agricultural landscapes, affects water quality is important when assessing the efficacy of mitigation measures. Investigation of this inherent time lag (t(T)) is divided into unsaturated (t(u)) and saturated (t(s)) components. The duration of these components relative to each other differs depending on soil characteristics and the landscape position. The present field study focuses on tu estimation in a scenario where the saturated zone is likely to constitute a higher proportion of t(T). In such instances, or where only initial breakthrough (IBT) or centre of mass (COM) is of interest, utilisation of site and depth specific "simple" textural class or actual sand-silt-clay percentages to generate soil water characteristic curves with associated soil hydraulic parameters is acceptable. With the same data it is also possible to estimate a soil physical quality (S) parameter for each soil layer which can be used to infer many other physical, chemical and biological quality indicators. In this study, hand texturing in the field was used to determine textural classes of a soil profile. Laboratory methods, including hydrometer, pipette and laser diffraction methods were used to determine actual sand-silt-clay percentages of sections of the same soil profile. Results showed that in terms of S, hand texturing resulted in a lower index value (inferring a degraded soil) than that of pipette, hydrometer and laser equivalents. There was no difference between S index values determined using the pipette, hydrometer and laser diffraction methods. The difference between the three laboratory methods on both the IBT and COM stages of t(u) were negligible, and in this instance were unlikely to affect either groundwater monitoring decisions, or to be of consequence from a policy perspective. When t(u) estimates are made over the full depth of the vadose zone, which may extend to several metres, errors resulting from

  16. Consequences of using different soil texture determination methodologies for soil physical quality and unsaturated zone time lag estimates

    Science.gov (United States)

    Fenton, O.; Vero, S.; Ibrahim, T. G.; Murphy, P. N. C.; Sherriff, S. C.; Ó hUallacháin, D.

    2015-11-01

    Elucidation of when the loss of pollutants, below the rooting zone in agricultural landscapes, affects water quality is important when assessing the efficacy of mitigation measures. Investigation of this inherent time lag (tT) is divided into unsaturated (tu) and saturated (ts) components. The duration of these components relative to each other differs depending on soil characteristics and the landscape position. The present field study focuses on tu estimation in a scenario where the saturated zone is likely to constitute a higher proportion of tT. In such instances, or where only initial breakthrough (IBT) or centre of mass (COM) is of interest, utilisation of site and depth specific "simple" textural class or actual sand-silt-clay percentages to generate soil water characteristic curves with associated soil hydraulic parameters is acceptable. With the same data it is also possible to estimate a soil physical quality (S) parameter for each soil layer which can be used to infer many other physical, chemical and biological quality indicators. In this study, hand texturing in the field was used to determine textural classes of a soil profile. Laboratory methods, including hydrometer, pipette and laser diffraction methods were used to determine actual sand-silt-clay percentages of sections of the same soil profile. Results showed that in terms of S, hand texturing resulted in a lower index value (inferring a degraded soil) than that of pipette, hydrometer and laser equivalents. There was no difference between S index values determined using the pipette, hydrometer and laser diffraction methods. The difference between the three laboratory methods on both the IBT and COM stages of tu were negligible, and in this instance were unlikely to affect either groundwater monitoring decisions, or to be of consequence from a policy perspective. When tu estimates are made over the full depth of the vadose zone, which may extend to several metres, errors resulting from the use of

  17. The economic impact of poor sample quality in clinical chemistry laboratories: results from a global survey.

    Science.gov (United States)

    Erdal, Erik P; Mitra, Debanjali; Khangulov, Victor S; Church, Stephen; Plokhoy, Elizabeth

    2017-03-01

    Background Despite advances in clinical chemistry testing, poor blood sample quality continues to impact laboratory operations and the quality of results. While previous studies have identified the preanalytical causes of lower sample quality, few studies have examined the economic impact of poor sample quality on the laboratory. Specifically, the costs associated with workarounds related to fibrin and gel contaminants remain largely unexplored. Methods A quantitative survey of clinical chemistry laboratory stakeholders across 10 international regions, including countries in North America, Europe and Oceania, was conducted to examine current blood sample testing practices, sample quality issues and practices to remediate poor sample quality. Survey data were used to estimate costs incurred by laboratories to mitigate sample quality issues. Results Responses from 164 participants were included in the analysis, which was focused on three specific issues: fibrin strands, fibrin masses and gel globules. Fibrin strands were the most commonly reported issue, with an overall incidence rate of ∼3%. Further, 65% of respondents indicated that these issues contribute to analyzer probe clogging, and the majority of laboratories had visual inspection and manual remediation practices in place to address fibrin- and gel-related quality problems (55% and 70%, respectively). Probe maintenance/replacement, visual inspection and manual remediation were estimated to carry significant costs for the laboratories surveyed. Annual cost associated with lower sample quality and remediation related to fibrin and/or gel globules for an average US laboratory was estimated to be $100,247. Conclusions Measures to improve blood sample quality present an important step towards improved laboratory operations.

  18. Implementation and results of an integrated data quality assurance protocol in a randomized controlled trial in Uttar Pradesh, India.

    Science.gov (United States)

    Gass, Jonathon D; Misra, Anamika; Yadav, Mahendra Nath Singh; Sana, Fatima; Singh, Chetna; Mankar, Anup; Neal, Brandon J; Fisher-Bowman, Jennifer; Maisonneuve, Jenny; Delaney, Megan Marx; Kumar, Krishan; Singh, Vinay Pratap; Sharma, Narender; Gawande, Atul; Semrau, Katherine; Hirschhorn, Lisa R

    2017-09-07

    There are few published standards or methodological guidelines for integrating Data Quality Assurance (DQA) protocols into large-scale health systems research trials, especially in resource-limited settings. The BetterBirth Trial is a matched-pair, cluster-randomized controlled trial (RCT) of the BetterBirth Program, which seeks to improve quality of facility-based deliveries and reduce 7-day maternal and neonatal mortality and maternal morbidity in Uttar Pradesh, India. In the trial, over 6300 deliveries were observed and over 153,000 mother-baby pairs across 120 study sites were followed to assess health outcomes. We designed and implemented a robust and integrated DQA system to sustain high-quality data throughout the trial. We designed the Data Quality Monitoring and Improvement System (DQMIS) to reinforce six dimensions of data quality: accuracy, reliability, timeliness, completeness, precision, and integrity. The DQMIS was comprised of five functional components: 1) a monitoring and evaluation team to support the system; 2) a DQA protocol, including data collection audits and targets, rapid data feedback, and supportive supervision; 3) training; 4) standard operating procedures for data collection; and 5) an electronic data collection and reporting system. Routine audits by supervisors included double data entry, simultaneous delivery observations, and review of recorded calls to patients. Data feedback reports identified errors automatically, facilitating supportive supervision through a continuous quality improvement model. The five functional components of the DQMIS successfully reinforced data reliability, timeliness, completeness, precision, and integrity. The DQMIS also resulted in 98.33% accuracy across all data collection activities in the trial. All data collection activities demonstrated improvement in accuracy throughout implementation. Data collectors demonstrated a statistically significant (p = 0.0004) increase in accuracy throughout

  19. Report on an Assessment of the Application of EPP Results from the Strain Limit Evaluation Procedure to the Prediction of Cyclic Life Based on the SMT Methodology

    Energy Technology Data Exchange (ETDEWEB)

    Jetter, R. I. [R. I. Jetter Consulting, Pebble Beach, CA (United States); Messner, M. C. [Argonne National Lab. (ANL), Argonne, IL (United States); Sham, T. -L. [Argonne National Lab. (ANL), Argonne, IL (United States); Wang, Y. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2017-08-01

    The goal of the proposed integrated Elastic Perfectly-Plastic (EPP) and Simplified Model Test (SMT) methodology is to incorporate an SMT data based approach for creep-fatigue damage evaluation into the EPP methodology to avoid the separate evaluation of creep and fatigue damage and eliminate the requirement for stress classification in current methods; thus greatly simplifying evaluation of elevated temperature cyclic service. This methodology should minimize over-conservatism while properly accounting for localized defects and stress risers. To support the implementation of the proposed methodology and to verify the applicability of the code rules, analytical studies and evaluation of thermomechanical test results continued in FY17. This report presents the results of those studies. An EPP strain limits methodology assessment was based on recent two-bar thermal ratcheting test results on 316H stainless steel in the temperature range of 405 to 7050C. Strain range predictions from the EPP evaluation of the two-bar tests were also evaluated and compared with the experimental results. The role of sustained primary loading on cyclic life was assessed using the results of pressurized SMT data from tests on Alloy 617 at 9500C. A viscoplastic material model was used in an analytic simulation of two-bar tests to compare with EPP strain limits assessments using isochronous stress strain curves that are consistent with the viscoplastic material model. A finite element model of a prior 304H stainless steel Oak Ridge National Laboratory (ORNL) nozzle-to-sphere test was developed and used for an EPP strain limits and creep-fatigue code case damage evaluations. A theoretical treatment of a recurring issue with convergence criteria for plastic shakedown illustrated the role of computer machine precision in EPP calculations.

  20. A multi-methodological approach to study the temporal and spatial distribution of air quality related to road transport emissions in Madrid, Spain

    Science.gov (United States)

    Perez, Pedro; Miranda, Regina

    2013-04-01

    The traffic-related atmospheric emissions, composition and transport of greenhouse gases (GHGs) and air toxic pollutants (ATPs), are an important environmental problem that affect climate change and air pollution in Madrid, Spain. Carbon dioxide (CO2) affects the regional weather and particularly fine particle matter (PM) translocate to the people resulting in local health problems. As the main source of emissions comes from road transport, and subsequent combustion of fossil fuels, air quality deterioration may be elevated during weekdays and peak hours. We postulate that traffic-related air quality (CO2, methane CH4, PM, volatile organic compounds VOCs, nitrogen oxides NOx and carbon monoxide CO contents) impairs epidemiology in part via effects on health and disease development, likely increasing the external costs of transport in terms of climate change and air pollution. First, the paper intends to estimate the local air quality related to the road transport emissions of weeks over a domain covering Madrid (used as a case study). The local air quality model (LAQM) is based on gridded and shaped emission fields. The European Environmental Agency (EEA) COPERT modeling system will provide GHGs and ATPs gridded and shaped emission data and mobile source parameters, available for Madrid from preliminary emission inventory records of the Municipality of Madrid and from disaggregated traffic counts of the Traffic Engineering Company and the Metropolitan Company of Metro (METRO-Madrid). The paper intends to obtain estimates of GHGs and ATPs concentrations commensurate with available ground measurements, 24-hour average values, from the Municipality of Madrid. The comparison between estimated concentrations and measurements must show small errors (e.g. fractional error, fractional bias and coefficient of determination). The paper's expected results must determine spatial and temporal patterns in Madrid. The estimates will be used to cross check the primary local

  1. European external quality control study on the competence of laboratories to recognize rare sequence variants resulting in unusual genotyping results.

    Science.gov (United States)

    Márki-Zay, János; Klein, Christoph L; Gancberg, David; Schimmel, Heinz G; Dux, László

    2009-04-01

    Depending on the method used, rare sequence variants adjacent to the single nucleotide polymorphism (SNP) of interest may cause unusual or erroneous genotyping results. Because such rare variants are known for many genes commonly tested in diagnostic laboratories, we organized a proficiency study to assess their influence on the accuracy of reported laboratory results. Four external quality control materials were processed and sent to 283 laboratories through 3 EQA organizers for analysis of the prothrombin 20210G>A mutation. Two of these quality control materials contained sequence variants introduced by site-directed mutagenesis. One hundred eighty-nine laboratories participated in the study. When samples gave a usual result with the method applied, the error rate was 5.1%. Detailed analysis showed that more than 70% of the failures were reported from only 9 laboratories. Allele-specific amplification-based PCR had a much higher error rate than other methods (18.3% vs 2.9%). The variants 20209C>T and [20175T>G; 20179_20180delAC] resulted in unusual genotyping results in 67 and 85 laboratories, respectively. Eighty-three (54.6%) of these unusual results were not recognized, 32 (21.1%) were attributed to technical issues, and only 37 (24.3%) were recognized as another sequence variant. Our findings revealed that some of the participating laboratories were not able to recognize and correctly interpret unusual genotyping results caused by rare SNPs. Our study indicates that the majority of the failures could be avoided by improved training and careful selection and validation of the methods applied.

  2. Creating a Methodology for Coordinating High-resolution Air Quality Improvement Map and Greenhouse Gas Mitigation Strategies in Pittsburgh City

    Science.gov (United States)

    Shi, J.; Donahue, N. M.; Klima, K.; Blackhurst, M.

    2016-12-01

    In order to tradeoff global impacts of greenhouse gases with highly local impacts of conventional air pollution, researchers require a method to compare global and regional impacts. Unfortunately, we are not aware of a method that allows these to be compared, "apples-to-apples". In this research we propose a three-step model to compare possible city-wide actions to reduce greenhouse gases and conventional air pollutants. We focus on Pittsburgh, PA, a city with consistently poor air quality that is interested in reducing both greenhouse gases and conventional air pollutants. First, we use the 2013 Pittsburgh Greenhouse Gas Inventory to update the Blackhurst et al. model and conduct a greenhouse gas abatement potentials and implementation costs of proposed greenhouse gas reduction efforts. Second, we use field tests for PM2.5, NOx, SOx, organic carbon (OC) and elemental carbon (EC) data to inform a Land-use Regression Model for local air pollution at a 100m x 100m spatial level, which combined with a social cost of air pollution model (EASIUR) allows us to calculate economic social damages. Third, we combine these two models into a three-dimensional greenhouse gas cost abatement curve to understand the implementation costs and social benefits in terms of air quality improvement and greenhouse gas abatement for each potential intervention. We anticipated such results could provide policy-maker insights in green city development.

  3. 78 FR 63972 - Notice of Proposed Methodology for the 2014 Delaware River and Bay Water Quality Assessment Report

    Science.gov (United States)

    2013-10-25

    ... Water Quality Assessment Report AGENCY: Delaware River Basin Commission. ACTION: Notice. SUMMARY: Notice....us , with ``Water Quality Assessment 2014'' as the subject line; via fax to 609-883-9522; via U.S. Mail to DRBC, Attn: Water Quality Assessment 2014, P.O. Box 7360, West Trenton, NJ 08628-0360; via...

  4. 76 FR 50188 - Notice of Proposed Methodology for the Delaware River and Bay Integrated List Water Quality...

    Science.gov (United States)

    2011-08-12

    ... Integrated List Water Quality Assessment AGENCY: Delaware River Basin Commission. ACTION: Notice. SUMMARY... Integrated List Water Quality Assessment is available for review and comment. DATES: Comments must be... should have the phrase ``Water Quality Assessment 2012'' in the subject line and should include the name...

  5. The COSMIN checklist for assessing the methodological quality of studies on measurement properties of health status measurement instruments: an international Delphi study.

    Science.gov (United States)

    Mokkink, Lidwine B; Terwee, Caroline B; Patrick, Donald L; Alonso, Jordi; Stratford, Paul W; Knol, Dirk L; Bouter, Lex M; de Vet, Henrica C W

    2010-05-01

    Aim of the COSMIN study (COnsensus-based Standards for the selection of health status Measurement INstruments) was to develop a consensus-based checklist to evaluate the methodological quality of studies on measurement properties. We present the COSMIN checklist and the agreement of the panel on the items of the checklist. A four-round Delphi study was performed with international experts (psychologists, epidemiologists, statisticians and clinicians). Of the 91 invited experts, 57 agreed to participate (63%). Panel members were asked to rate their (dis)agreement with each proposal on a five-point scale. Consensus was considered to be reached when at least 67% of the panel members indicated 'agree' or 'strongly agree'. Consensus was reached on the inclusion of the following measurement properties: internal consistency, reliability, measurement error, content validity (including face validity), construct validity (including structural validity, hypotheses testing and cross-cultural validity), criterion validity, responsiveness, and interpretability. The latter was not considered a measurement property. The panel also reached consensus on how these properties should be assessed. The resulting COSMIN checklist could be useful when selecting a measurement instrument, peer-reviewing a manuscript, designing or reporting a study on measurement properties, or for educational purposes.

  6. Study of methodologies for quality control of 99Mo used in 99Mo/99mTc generators

    International Nuclear Information System (INIS)

    Said, Daphne de Souza

    2016-01-01

    99m Tc is the most used radionuclide in nuclear medicine. In Brazil, the 99 Mo/ 99m Tc generators are exclusively produced by Radiopharmacy Center at IPEN-CNEN/ SP, by importing 99 Mo from different suppliers. 99 Mo (t 1/2 = 66 h) is a fission product of 235 U and it can have radionuclidic impurities that are prejudicial for human health. For safe use of generators, it is necessary to perform the evaluation of 99 Mo by quality control tests in order to assess if 99 Mo complies with the specifications. The European Pharmacopoeia (EP) presents a monograph for evaluation of the quality of the [ 99 Mo] solution as sodium molybdate,that is used as raw material for 99 Mo/ 99m Tc generators production, including specification parameters (identification, radiochemical purity and radionuclidic purity), analysis methods and limits. However, it has been observed difficulties on the execution and implementation of these methods by the generators producers, with a few literature about this subject, probably due to complexity of the proposed methods. In this work, many quality control parameters of 99 Mo described in the EP monograph were evaluated. Separation methods for 99M o from its radionuclidic impurities by solid phase extraction (SPE) and TLC were studied. After SPE separation, the quantification of metals by ICP-OES to evaluate the percentage of retention of Mo and the percentage of recovery of Ru, Te and Sr using different types of cartridges were proposed, replacing radiotracers use. It was observed that the specific type of SPE cartridge recommended by the EP for separation of 99 Mo presented low recoveries for Ru, compared to other available anion exchange SPE cartridges. 99 Mo samples from different worldwide suppliers were analyzed. It was observed that quantification of 103 Ru in 99 Mo samples with decay time higher than 4 weeks is possible. An alternative method for separation of 131 I from 99 Mo showed promising results by TLC. The quantification of beta and

  7. Quality index of radiological devices: results of one year of use.

    Science.gov (United States)

    Tofani, Alessandro; Imbordino, Patrizia; Lecci, Antonio; Bonannini, Claudia; Del Corona, Alberto; Pizzi, Stefano

    2003-01-01

    The physical quality index (QI) of radiological devices summarises in a single numerical value between 0 and 1 the results of constancy tests. The aim of this paper is to illustrate the results of the use of such an index on all public radiological devices in the Livorno province over one year. The quality index was calculated for 82 radiological devices of a wide range of types by implementing its algorithm in a spreadsheet-based software for the automatic handling of quality control data. The distribution of quality index values was computed together with the associated statistical quantities. This distribution is strongly asymmetrical, with a sharp peak near the highest QI values. The mean quality index values for the different types of device show some inhomogeneity: in particular, mammography and panoramic dental radiography devices show far lower quality than other devices. In addition, our analysis has identified the parameters that most frequently do not pass the quality tests for each type of device. Finally, we sought some correlation between quality and age of the device, but this was poorly significant. The quality index proved to be a useful tool providing an overview of the physical conditions of radiological devices. By selecting adequate QI threshold values for, it also helps to decide whether a given device should be upgraded or replaced. The identification of critical parameters for each type of device may be used to improve the definition of the QI by attributing greater weights to critical parameters, so as to better address the maintenance of radiological devices.

  8. Impact of methodological choices on findings from pharmacoepidemiological studies: Final results of the IMI-protect (pharmacoepidemiological research on outcomes of therapeutics by a European consortium) project

    OpenAIRE

    Klungel, Olaf; De Groot, Mark; Gardarsdottir, Helga; Brauer, Ruth; Grimaldi-Bensouda, Lamiae; Kurz, Xavier; Gasse, Christiane; Reynolds, Robert

    2014-01-01

    Background: Pharmacoepidemiological (PE) research should provide consistent, reliable and reproducible results to contribute to the benefit-risk assessment of medicines. IMI-PROTECT aims to identify sources of methodological variations in PE studies using a common protocol and analysis plan across databases (including independent replication studies). In addition, differences by design, applied to a same drug-adverse event (AE) pair in different databases are examined. Results from PE studies...

  9. [Analysis of the results of the SEIMC External Quality Control Program. Year 2013].

    Science.gov (United States)

    de Gopegui Bordes, Enrique Ruiz; Orta Mira, Nieves; Del Remedio Guna Serrano, M; Medina González, Rafael; Rosario Ovies, María; Poveda, Marta; Gimeno Cardona, Concepción

    2015-07-01

    The External Quality Control Program of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) include controls for bacteriology, serology, mycology, parasitology, mycobacteria, virology, molecular microbiology and HIV-1, HCV and HBV viral loads. This manuscript presents the analysis of results obtained of the participants from the 2013 SEIMC External Quality Control Programme, except viral loads controls, that they are summarized in a manuscript abroad. As a whole, the results obtained in 2013 confirm the excellent skill and good technical standards found in previous editions. However, erroneous results can be obtained in any laboratory and in clinically relevant determinations. Once again, the results of this program highlighted the need to implement both internal and external controls in order to assure the maximal quality of the microbiological tests. Copyright © 2015 Elsevier España, S.L.U. All rights reserved.

  10. Shear wave velocity versus quality factor: results from seismic noise recordings

    Science.gov (United States)

    Boxberger, Tobias; Pilz, Marco; Parolai, Stefano

    2017-08-01

    The assessment of the shear wave velocity (vs) and shear wave quality factor (Qs) for the shallow structure below a site is necessary to characterize its site response. In the past, methods based on the analysis of seismic noise have been shown to be very efficient for providing a sufficiently accurate estimation of the vs versus depth at reasonable costs for engineering seismology purposes. In addition, a slight modification of the same method has proved to be able to provide realistic Qs versus depth estimates. In this study, data sets of seismic noise recorded by microarrays of seismic stations in different geological environments of Europe and Central Asia are used to calculate both vs and Qs versus depth profiles. Analogous to the generally adopted approach in seismic hazard assessment for mapping the average shear wave velocity in the uppermost 30 m (vs30) as a proxy of the site response, this approach was also applied to the quality factor within the uppermost 30 m (Qs30). A slightly inverse correlation between both parameters is found based on a methodological consistent determination for different sites. Consequently, a combined assessment of vs and Qs by seismic noise analysis has the potential to provide a more comprehensive description of the geological structure below a site.

  11. SU-E-T-43: A Methodology for Quality Control of IMPT Treatment Plan Based On VMAT Plan

    Energy Technology Data Exchange (ETDEWEB)

    Jiang, S [UT MD Anderson Cancer Center (United States); Tianjin Medical University Cancer Institute and Hospital (China); Yang, Y [UT MD Anderson Cancer Center (United States); Tianjin First Center Hospital (China); Liao, L; Wang, X; Li, H; Zhu, X; Zhang, X [UT MD Anderson Cancer Center (United States)

    2015-06-15

    Purpose: IMPT plan design is highly dependent on planner’s experiences. VMAT plan design is relatively mature and can even be automated. The quality of IMPT plan designed by in-experienced planner could be inferior to that of VMAT plan designed by experienced planner or automatic planning software. Here we introduce a method for designing IMPT plan based on VMAT plan to ensure the IMPT plan be superior to IMRT/VMAT plan for majority clinical scenario. Methods: To design a new IMPT plan, a VMAT plan is first generated either by experienced planner or by in-house developed automatic planning system. An in-house developed tool is used to generate the dose volume constrains for the IMPT plan as plan template to Eclipse TPS. The beam angles for IMPT plan are selected based on the preferred angles in the VMAT plan. IMPT plan is designed by importing the plan objectives generated from VMAT plan. Majority thoracic IMPT plans are designed using this plan approach in our center. In this work, a thoracic IMPT plan under RTOG 1308 protocol is selected to demonstrate the effectiveness and efficiency of this approach. The dosimetric indices of IMPT are compared with VMAT plan. Results: The PTV D95, lung V20, MLD, mean heart dose, esophagus D1, cord D1 are 70Gy, 31%, 17.8Gy, 25.5Gy, 73Gy, 45Gy for IMPT plan and 65.3Gy, 34%, 21.6Gy, 35Gy, 74Gy, 48Gy for VMAT plan. For majority cases, the high dose region of the normal tissue which is in proximity of PTV is comparable between IMPT and VMAT plan. The low dose region of the IMPT plan is significantly better than VMAT plan. Conclusion: Using the knowledge gained in VMAT plan design can help efficiently and effectively design high quality IMPT plan. The quality of IMPT plan can be controlled to ensure the superiority of IMPT plan compared to VMAT/IMRT plan.

  12. SU-E-T-43: A Methodology for Quality Control of IMPT Treatment Plan Based On VMAT Plan

    International Nuclear Information System (INIS)

    Jiang, S; Yang, Y; Liao, L; Wang, X; Li, H; Zhu, X; Zhang, X

    2015-01-01

    Purpose: IMPT plan design is highly dependent on planner’s experiences. VMAT plan design is relatively mature and can even be automated. The quality of IMPT plan designed by in-experienced planner could be inferior to that of VMAT plan designed by experienced planner or automatic planning software. Here we introduce a method for designing IMPT plan based on VMAT plan to ensure the IMPT plan be superior to IMRT/VMAT plan for majority clinical scenario. Methods: To design a new IMPT plan, a VMAT plan is first generated either by experienced planner or by in-house developed automatic planning system. An in-house developed tool is used to generate the dose volume constrains for the IMPT plan as plan template to Eclipse TPS. The beam angles for IMPT plan are selected based on the preferred angles in the VMAT plan. IMPT plan is designed by importing the plan objectives generated from VMAT plan. Majority thoracic IMPT plans are designed using this plan approach in our center. In this work, a thoracic IMPT plan under RTOG 1308 protocol is selected to demonstrate the effectiveness and efficiency of this approach. The dosimetric indices of IMPT are compared with VMAT plan. Results: The PTV D95, lung V20, MLD, mean heart dose, esophagus D1, cord D1 are 70Gy, 31%, 17.8Gy, 25.5Gy, 73Gy, 45Gy for IMPT plan and 65.3Gy, 34%, 21.6Gy, 35Gy, 74Gy, 48Gy for VMAT plan. For majority cases, the high dose region of the normal tissue which is in proximity of PTV is comparable between IMPT and VMAT plan. The low dose region of the IMPT plan is significantly better than VMAT plan. Conclusion: Using the knowledge gained in VMAT plan design can help efficiently and effectively design high quality IMPT plan. The quality of IMPT plan can be controlled to ensure the superiority of IMPT plan compared to VMAT/IMRT plan

  13. Implications of the Integration of Computing Methodologies into Conventional Marketing Research upon the Quality of Students' Understanding of the Concept

    Science.gov (United States)

    Ayman, Umut; Serim, Mehmet Cenk

    2004-01-01

    It has been an ongoing concern among academicians teaching social sciences to develop a better methodology to ease understanding of students. Since verbal emphasis is at the core of the concepts within such disciplines it has been observed that the adequate or desired level of conceptual understanding of the students to transforms the theories…

  14. Explaining variation in perceived team effectiveness: results from eleven quality improvement collaboratives.

    Science.gov (United States)

    Strating, Mathilde M H; Nieboer, Anna P

    2013-06-01

    Explore effectiveness of 11 collaboratives focusing on 11 different topics, as perceived by local improvement teams and to explore associations with collaborative-, organisational- and team-level factors. Evidence underlying the effectiveness of quality improvement collaboratives is inconclusive and few studies investigated determinants of implementation success. Moreover, most evaluation studies on quality improvement collaboratives are based on one specific topic or quality problem, making it hard to compare across collaboratives addressing different topics. A multiple-case cross-sectional study. Quality improvement teams in 11 quality improvement collaboratives focusing on 11 different topics. Team members received a postal questionnaire at the end of each collaborative. Of the 283 improvement teams, 151 project leaders and 362 team members returned the questionnaire. Analysis of variance revealed that teams varied widely on perceived effectiveness. Especially, members in the Prevention of Malnutrition and Prevention of Medication Errors collaboratives perceived a higher effectiveness than other groups. Multilevel regression analyses showed that educational level of professionals, innovation attributes, organisational support, innovative culture and commitment to change were all significant predictors of perceived effectiveness. In total, 27·9% of the individual-level variance, 57·6% of the team-level variance and 80% of the collaborative-level variance could be explained. The innovation's attributes, organisational support, an innovative team culture and professionals' commitment to change are instrumental to perceived effectiveness. The results support the notion that a layered approach is necessary to achieve improvements in quality of care and provides further insight in the determinants of success of quality improvement collaboratives. Understanding which factors enhance the impact of quality improvement initiatives can help professionals to achieve

  15. Quantification of Greenhouse Gas Emission Rates from strong Point Sources by Airborne IPDA-Lidar Measurements: Methodology and Experimental Results

    Science.gov (United States)

    Ehret, G.; Amediek, A.; Wirth, M.; Fix, A.; Kiemle, C.; Quatrevalet, M.

    2016-12-01

    We report on a new method and on the first demonstration to quantify emission rates from strong greenhouse gas (GHG) point sources using airborne Integrated Path Differential Absorption (IPDA) Lidar measurements. In order to build trust in the self-reported emission rates by countries, verification against independent monitoring systems is a prerequisite to check the reported budget. A significant fraction of the total anthropogenic emission of CO2 and CH4 originates from localized strong point sources of large energy production sites or landfills. Both are not monitored with sufficiently accuracy by the current observation system. There is a debate whether airborne remote sensing could fill in the gap to infer those emission rates from budgeting or from Gaussian plume inversion approaches, whereby measurements of the GHG column abundance beneath the aircraft can be used to constrain inverse models. In contrast to passive sensors, the use of an active instrument like CHARM-F for such emission verification measurements is new. CHARM-F is a new airborne IPDA-Lidar devised for the German research aircraft HALO for the simultaneous measurement of the column-integrated dry-air mixing ratio of CO2 and CH4 commonly denoted as XCO2 und XCH4, respectively. It has successfully been tested in a serious of flights over Central Europe to assess its performance under various reflectivity conditions and in a strongly varying topography like the Alps. The analysis of a methane plume measured in crosswind direction of a coal mine ventilation shaft revealed an instantaneous emission rate of 9.9 ± 1.7 kt CH4 yr-1. We discuss the methodology of our point source estimation approach and give an outlook on the CoMet field experiment scheduled in 2017 for the measurement of anthropogenic and natural GHG emissions by a combination of active and passive remote sensing instruments on research aircraft.

  16. Use of Multiple Methodologies for Developing a Customer-Oriented Model of Total Quality Management in Higher Education

    Science.gov (United States)

    Sahney, Sangeeta

    2016-01-01

    Purpose: Educational institutes must embrace the principles of total quality management (TQM) if they seek to remain competitive, and survive and succeed in the long run. An educational institution must embrace the principles of quality management and incorporate them into all of their activities. Starting with a theoretical background, the paper…

  17. A review of quality assessment of the methodology used in guidelines and systematic reviews on oral mucositis.

    NARCIS (Netherlands)

    Potting, C.; Mistiaen, P.; Poot, E.; Blijlevens, N.; Donnelly, P.; Achterberg, T. van

    2009-01-01

    Aims and objectives: The objective of this study was to identify and to assess the quality of evidence-based guidelines and systematic reviews we used in the case of oral mucositis, to apply general quality criteria for the prevention and treatment of oral mucositis in patients receiving

  18. PRELIMINARY RESULTS OF QUALITY STUDY OF WATER FROM SMALL MICHALICE RESERVOIR ON WIDAWA RIVER

    Directory of Open Access Journals (Sweden)

    Mirosław Wiatkowski

    2014-10-01

    Full Text Available The paper presents an analysis of water quality of the small Michalice reservoir. A preliminary assessment of the reservoir water quality and its usability was made. The quality of water in the reservoir is particularly important as the main functions of the reservoir are agricultural irrigation, recreation and flood protection . The following physico-chemical parameters of the Widawa River were analyzed: NO3 -, NO2 -, NH4 +, PO4 3-, COD, water temperature, pH and electrolytic conductivity. Main descriptive statistical data were presented for the analyzed water quality indicators. The research results indicate that the reservoir contributed to the reduced concentrations of the following water quality indicators: nitrates, nitrites, phosphates, electrolytic conductivity and COD (in the outflowing water – St.3 in comparison to the water flowing into the reservoir – St.1. In the water flowing out of the Psurów reservoir higher values of the remaining indicators were observed if compared with the inflowing water. It was stated, as well, that analised waters are not vulnerable to nitrogen compounds pollution coming from the agricultural sources and are eutrophic. For purpose obtaining of the précised information about condition of Michalice reservoir water purity as well as river Widawa it becomes to continue the hydrological monitoring and water quality studies.

  19. Colostomy irrigation: results of 25 cases with particular reference to quality of life.

    Science.gov (United States)

    Karadağ, Ayişe; Menteş, B Bülent; Ayaz, Sultan

    2005-04-01

    The aim of this study was to document our results with colostomy irrigation with particular emphasis on the possible contribution of irrigation on quality of life. Colostomy irrigation is a useful method of achieving faecal continence in selected conditions, and may improve quality of life. When successful, irrigation offers a regular, predictable elimination pattern and only a small covering is needed for security between irrigations. The digestive disease quality of life questionnaire-15 (DDQ-15) and Short Form-36 were used to analyse quality of life before and 12 months after stomatherapy in a series of 25 irrigating patients with permanent end colostomies. During the same time period, 10 similar patients with left-end colostomies who also received counselling but did not consent to colostomy irrigation were also analysed for comparison. Colostomy irrigation was found to be effective for achieving faecal continence in selected patients with end colostomies with no complications or significant side-effects, The digestive disease quality of life questionnaire-15 score improved significantly in both groups after stomatherapy (P colostomy irrigation can be a useful method of achieving faecal continence in selected conditions, it is safe, and it may help improve many aspects of quality of life. Colostomy irrigation is free from complications and significant side-effects, and it may serve as a useful adjunct to conventional stomatherapy. Therefore, the enterostomal therapy nurse should assess the appropriateness of routine irrigation as a method of stoma management for patients with left-end colostomy.

  20. How often do German children and adolescents show signs of common mental health problems? Results from different methodological approaches – a cross-sectional study

    OpenAIRE

    Sauer, Kristin; Barkmann, Claus; Klasen, Fionna; Bullinger, Monika; Glaeske, Gerd; Ravens-Sieberer, Ulrike

    2014-01-01

    Background Child and adolescent mental health problems are ubiquitous and burdensome. Their impact on functional disability, the high rates of accompanying medical illnesses and the potential to last until adulthood make them a major public health issue. While methodological factors cause variability of the results from epidemiological studies, there is a lack of prevalence rates of mental health problems in children and adolescents according to ICD-10 criteria from nationally representative ...

  1. Influence of raw milk quality on processed dairy products: How do raw milk quality test results relate to product quality and yield?

    Science.gov (United States)

    Murphy, Steven C; Martin, Nicole H; Barbano, David M; Wiedmann, Martin

    2016-12-01

    This article provides an overview of the influence of raw milk quality on the quality of processed dairy products and offers a perspective on the merits of investing in quality. Dairy farmers are frequently offered monetary premium incentives to provide high-quality milk to processors. These incentives are most often based on raw milk somatic cell and bacteria count levels well below the regulatory public health-based limits. Justification for these incentive payments can be based on improved processed product quality and manufacturing efficiencies that provide the processor with a return on their investment for high-quality raw milk. In some cases, this return on investment is difficult to measure. Raw milks with high levels of somatic cells and bacteria are associated with increased enzyme activity that can result in product defects. Use of raw milk with somatic cell counts >100,000cells/mL has been shown to reduce cheese yields, and higher levels, generally >400,000 cells/mL, have been associated with textural and flavor defects in cheese and other products. Although most research indicates that fairly high total bacteria counts (>1,000,000 cfu/mL) in raw milk are needed to cause defects in most processed dairy products, receiving high-quality milk from the farm allows some flexibility for handling raw milk, which can increase efficiencies and reduce the risk of raw milk reaching bacterial levels of concern. Monitoring total bacterial numbers in regard to raw milk quality is imperative, but determining levels of specific types of bacteria present has gained increasing importance. For example, spores of certain spore-forming bacteria present in raw milk at very low levels (e.g., products to levels that result in defects. With the exception of meeting product specifications often required for milk powders, testing for specific spore-forming groups is currently not used in quality incentive programs in the United States but is used in other countries (e.g., the

  2. Quality-assurance results for routine water analysis in US Geological Survey laboratories, water year 1991

    Science.gov (United States)

    Maloney, T.J.; Ludtke, A.S.; Krizman, T.L.

    1994-01-01

    The US. Geological Survey operates a quality- assurance program based on the analyses of reference samples for the National Water Quality Laboratory in Arvada, Colorado, and the Quality of Water Service Unit in Ocala, Florida. Reference samples containing selected inorganic, nutrient, and low ionic-strength constituents are prepared and disguised as routine samples. The program goal is to determine precision and bias for as many analytical methods offered by the participating laboratories as possible. The samples typically are submitted at a rate of approximately 5 percent of the annual environmental sample load for each constituent. The samples are distributed to the laboratories throughout the year. Analytical data for these reference samples reflect the quality of environmental sample data produced by the laboratories because the samples are processed in the same manner for all steps from sample login through data release. The results are stored permanently in the National Water Data Storage and Retrieval System. During water year 1991, 86 analytical procedures were evaluated at the National Water Quality Laboratory and 37 analytical procedures were evaluated at the Quality of Water Service Unit. An overall evaluation of the inorganic (major ion and trace metal) constituent data for water year 1991 indicated analytical imprecision in the National Water Quality Laboratory for 5 of 67 analytical procedures: aluminum (whole-water recoverable, atomic emission spectrometric, direct-current plasma); calcium (atomic emission spectrometric, direct); fluoride (ion-exchange chromatographic); iron (whole-water recoverable, atomic absorption spectrometric, direct); and sulfate (ion-exchange chromatographic). The results for 11 of 67 analytical procedures had positive or negative bias during water year 1991. Analytical imprecision was indicated in the determination of two of the five National Water Quality Laboratory nutrient constituents: orthophosphate as phosphorus and

  3. Testing the validity of a translated pharmaceutical therapy-related quality of life instrument, using qualitative 'think aloud' methodology.

    Science.gov (United States)

    Renberg, T; Kettis Lindblad, A; Tully, M P

    2008-06-01

    In pharmacy practice, there is a need for valid and reliable instruments to study patient-reported outcomes. One potential candidate is a pharmaceutical therapy-related quality of life (PTRQoL) instrument. This study explored the face and content validity, including cognitive aspects of question answering of a PTRQoL instrument, translated from English to Swedish. A sample of 16 customers at Swedish community pharmacies, was asked to fill in the PTRQoL instrument while constantly reporting how they reasoned. The resulting interviews and concurrent probing, were audio-taped, transcribed verbatim and analysed using constant comparison method. The relation between the measurement and its theoretical underpinning was challenged. Respondents neglected to read the instructions, used response options in an unpredictable way, and varied in their interpretations of the items. The combination of 'think-aloud', retrospective probing and qualitative analysis informed on the validity of the PTRQoL instrument and was valuable in questionnaire development. The study also identified specific problems that could be relevant for other instruments probing patients' medicines-related attitudes and behaviour.

  4. [Criteria catalogue to systematize conceptual approaches in universal prevention of childhood overweight : Methodological approach and first results].

    Science.gov (United States)

    Babitsch, Birgit; Geene, Raimund; Hassel, Holger; Kliche, Thomas; Bacchetta, Britta; Baltes, Simon; Nold, Sandra; Rosenfeldt, Daniel

    2016-11-01

    Overweight and obesity are serious health risks for children and adolescents. Hence, various prevention projects have been initiated and implemented. Until now, a systematic overview of interventions in different settings has been lacking. The aim of the "Prevention of child overweight" project (SkAP-project) is to prepare a systematic overview of the conceptual approaches used in universal prevention of overweight among children and adolescents. First of all, a comprehensive criteria catalogue will be developed based on systematic searches. In the next step the criteria catalogue will be applied to identify and characterize conceptual approaches. Criteria to describe conceptual approaches as well as determinants of childhood overweight were determined by systematic searches. The searches included relevant data bases and were further expanded by internet and hand search. Three settings (kindergarten, school and communities) and families are addressed by the systematic searches. Additional non-setting specific searches were conducted. A comprehensive criteria catalogue was developed, which allows a detailed analysis of conceptual approaches. This catalogue covers further quality criteria as well as determinants of childhood overweight. Currently, the criteria catalogue is being employed. Although the detailed analysis of conceptual approaches can be regarded as advantage of the criteria catalogue, there are also some limitations, such as the lack of necessary information provided in publications. Overall, the application will reveal an overview regarding universal prevention in childhood overweight, which is still lacking, and will support development in this field.

  5. Methodological issues of genetic association studies.

    Science.gov (United States)

    Simundic, Ana-Maria

    2010-12-01

    Genetic association studies explore the association between genetic polymorphisms and a certain trait, disease or predisposition to disease. It has long been acknowledged that many genetic association studies fail to replicate their initial positive findings. This raises concern about the methodological quality of these reports. Case-control genetic association studies often suffer from various methodological flaws in study design and data analysis, and are often reported poorly. Flawed methodology and poor reporting leads to distorted results and incorrect conclusions. Many journals have adopted guidelines for reporting genetic association studies. In this review, some major methodological determinants of genetic association studies will be discussed.

  6. Technical aspects of quality assurance in mammography: Preliminary results from Serbia

    Directory of Open Access Journals (Sweden)

    Živković Monika M.

    2010-01-01

    Full Text Available Mammography is the method of choice for early detection of breast cancer. In Serbia, mammography is performed only clinically, although there is a plan to introduce mammography as a screening method. Currently, there are 60 mammographic units in practice, resulting in 70 000 mammographies annually. The survey was conducted in order to investigate mammographic practice in Serbia, identify weak points and suggest appropriate corrective measures. Basic technical parameters of the X-ray tube and generator, processing, image quality, and patient doses in 20 mammographic units were studied. The survey demonstrated considerable variations in technical parameters that affect image quality, and patients doses. Patient dose levels, in terms of the mean glandular dose, were fairly consistent with current European reference levels: 1.8 (0.40-4.3 mGy. However, due to inappropriate image receptors, image processing and viewing conditions and automatic exposure control adjustment, suboptimal image quality was a common finding. Simple improvements of the radiographic technique and maintenance procedure, along with the rigid implementation of the quality control procedure and training of the operating staff, would improve the performance levels of mammographic practice in Serbia, i. e. result in the production of high quality images with a reasonably low radiation risk to patients.

  7. Methodological issues and research recommendations for prognosis after mild traumatic brain injury: results of the International Collaboration on Mild Traumatic Brain Injury Prognosis.

    Science.gov (United States)

    Kristman, Vicki L; Borg, Jörgen; Godbolt, Alison K; Salmi, L Rachid; Cancelliere, Carol; Carroll, Linda J; Holm, Lena W; Nygren-de Boussard, Catharina; Hartvigsen, Jan; Abara, Uko; Donovan, James; Cassidy, J David

    2014-03-01

    The International Collaboration on Mild Traumatic Brain Injury (MTBI) Prognosis performed a comprehensive search and critical review of the literature from 2001 to 2012 to update the 2002 best-evidence synthesis conducted by the World Health Organization Collaborating Centre for Neurotrauma, Prevention, Management and Rehabilitation Task Force on the prognosis of MTBI. Of 299 relevant studies, 101 were accepted as scientifically admissible. The methodological quality of the research literature on MTBI prognosis has not improved since the 2002 Task Force report. There are still many methodological concerns and knowledge gaps in the literature. Here we report and make recommendations on how to avoid methodological flaws found in prognostic studies of MTBI. Additionally, we discuss issues of MTBI definition and identify topic areas in need of further research to advance the understanding of prognosis after MTBI. Priority research areas include but are not limited to the use of confirmatory designs, studies of measurement validity, focus on the elderly, attention to litigation/compensation issues, the development of validated clinical prediction rules, the use of MTBI populations other than hospital admissions, continued research on the effects of repeated concussions, longer follow-up times with more measurement periods in longitudinal studies, an assessment of the differences between adults and children, and an account for reverse causality and differential recall bias. Well-conducted studies in these areas will aid our understanding of MTBI prognosis and assist clinicians in educating and treating their patients with MTBI. Copyright © 2014 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.

  8. Comparison of the results for quality implementation of low energy X rays

    International Nuclear Information System (INIS)

    Affonseca, M; Ochoa, R; Almeida, C.E. de; Peixoto, J.G.

    2001-01-01

    It describes the comparison of the results for qualities implementation of low energy X rays, using a pan tak tube, HF 160, which has tungsten white, beryllium window, is water-cooled and it has a 160 K B generator [es

  9. F-15 inlet/engine test techniques and distortion methodologies studies. Volume 2: Time variant data quality analysis plots

    Science.gov (United States)

    Stevens, C. H.; Spong, E. D.; Hammock, M. S.

    1978-01-01

    Time variant data quality analysis plots were used to determine if peak distortion data taken from a subscale inlet model can be used to predict peak distortion levels for a full scale flight test vehicle.

  10. Results of the groundwater quality assessment program at the 216-A-29 ditch RCRA facility

    International Nuclear Information System (INIS)

    Votava, J.M.

    1995-01-01

    This report presents the findings of the groundwater quality assessment program for the 216-A-29 Ditch. The information presented in this report Ditch have affected the quality of the groundwater in the unconfined aquifer beneath the facility. The results indicate that the 216-A-29 Ditch is the source of elevated specific conductance in well 299-E25-35 and that the source is nonhazardous. This report describes the current monitoring status of the 216-A-29 Ditch, groundwater chemical data interpretation, and recommends the reinstatement of an indicator-evaluation monitoring program in accordance with 40 CFR 265.93(d)(6)

  11. The Satellite based Monitoring Initiative for Regional Air quality (SAMIRA): Project summary and first results

    Science.gov (United States)

    Schneider, Philipp; Stebel, Kerstin; Ajtai, Nicolae; Diamandi, Andrei; Horalek, Jan; Nemuc, Anca; Stachlewska, Iwona; Zehner, Claus

    2017-04-01

    We present a summary and some first results of a new ESA-funded project entitled Satellite based Monitoring Initiative for Regional Air quality (SAMIRA), which aims at improving regional and local air quality monitoring through synergetic use of data from present and upcoming satellite instruments, traditionally used in situ air quality monitoring networks and output from chemical transport models. Through collaborative efforts in four countries, namely Romania, Poland, the Czech Republic and Norway, all with existing air quality problems, SAMIRA intends to support the involved institutions and associated users in their national monitoring and reporting mandates as well as to generate novel research in this area. The primary goal of SAMIRA is to demonstrate the usefulness of existing and future satellite products of air quality for improving monitoring and mapping of air pollution at the regional scale. A total of six core activities are being carried out in order to achieve this goal: Firstly, the project is developing and optimizing algorithms for the retrieval of hourly aerosol optical depth (AOD) maps from the Spinning Enhanced Visible and InfraRed Imager (SEVIRI) onboard of Meteosat Second Generation. As a second activity, SAMIRA aims to derive particulate matter (PM2.5) estimates from AOD data by developing robust algorithms for AOD-to-PM conversion with the support from model- and Lidar data. In a third activity, we evaluate the added value of satellite products of atmospheric composition for operational European-scale air quality mapping using geostatistics and auxiliary datasets. The additional benefit of satellite-based monitoring over existing monitoring techniques (in situ, models) is tested by combining these datasets using geostatistical methods and demonstrated for nitrogen dioxide (NO2), sulphur dioxide (SO2), and aerosol optical depth/particulate matter. As a fourth activity, the project is developing novel algorithms for downscaling coarse

  12. Quality control methodology and implementation of X-radiation standards beams, mammography level, following the standard IEC 61267

    International Nuclear Information System (INIS)

    Correa, Eduardo de Lima

    2010-01-01

    In this work it was developed and applied a quality control program of the X radiation system (160 kV, constant potential, target of tungsten) of the Calibration Laboratory of IPEN(LCI) in the energy range relative to mammography beams (from 25 kV to 35 kV). The X radiation standards beams, level mammography, using molybdenum and aluminum as additional filtration, were established after the application of this quality control program following national and international recommendations. The reference ionization chamber has traceability to PTB and was regularly submitted to quality control tests for evaluation and analysis of its performance. The radiation qualities emerging from the X-radiation assembly (RQR-M), based on a phantom made up of an aluminum added filter (RQA-M), narrow beam condition (RQN-M) and broad beam condition (RQB-M), following the recommendations of the international standard IEC 61267 (2005) and the IAEA code of practice, TRS 457 (2007) were established. For the implantation of RQN-M and RQB-M radiation qualities, two mammography phantoms were developed. The half-value layers found are those presented by the German primary laboratory PTB, and varied from 0.35 to 1.21 mm Al. The air kerma rates were obtained for all the 15 implanted qualities. (author)

  13. Heterogeneity in pineapple fruit quality results from plant heterogeneity at flower induction.

    Science.gov (United States)

    Fassinou Hotegni, V Nicodème; Lommen, Willemien J M; Agbossou, Euloge K; Struik, Paul C

    2014-01-01

    Heterogeneity in fruit quality constitutes a major constraint in agri-food chains. In this paper the sources of the heterogeneity in pineapple in the field were studied in four experiments in commercial pineapple fields. The aims were to determine (a) whether differences in pineapple fruit quality among individual fruits are associated with differences in vigor of the individual plants within the crop at the time of artificial flower induction; and (b) whether the side shoots produced by the plant during the generative phase account for the fruit quality heterogeneity. Two pineapple cultivars were considered: cv. Sugarloaf and cv. Smooth Cayenne. Plant vigor at the time of artificial flower induction was measured by three variates: the number of functional leaves, the D-leaf length and their cross product. Fruit quality attributes measured at harvest time included external attributes (weight and height of fruit, infructescence and crown) and internal quality attributes [total soluble solids (TSS), pH, translucent flesh]. Results showed that the heterogeneity in fruit weight was a consequence of the heterogeneity in vigor of the plants at the moment of flower induction; that effect was mainly on the infructescence weight and less or not on the crown weight. The associations between plant vigor variates at flower induction and the internal quality attributes of the fruit were poor and/or not consistent across experiments. The weight of the slips (side shoots) explained part of the heterogeneity in fruit weight, infructescence weight and fruit height in cv. Sugarloaf. Possibilities for reducing the variation in fruit quality by precise cultural practices are discussed.

  14. Heterogeneity in pineapple fruit quality results from plant heterogeneity at flower induction

    Directory of Open Access Journals (Sweden)

    V. Nicodeme eFassinou Hotegni

    2014-12-01

    Full Text Available Heterogeneity in fruit quality constitutes a major constraint in agri-food chains. In this paper the sources of the heterogeneity in pineapple in the field were studied in four experiments in commercial pineapple fields. The aims were to determine (a whether differences in pineapple fruit quality among individual fruits are associated with differences in vigor of the individual plants within the crop at the time of artificial flower induction; and (b whether the side shoots produced by the plant during the generative phase account for the fruit quality heterogeneity. Two pineapple cultivars were considered: cv. Sugarloaf and cv. Smooth Cayenne. Plant vigor at the time of artificial flower induction was measured by three variates: the number of functional leaves, the D-leaf length and their cross product. Fruit quality attributes measured at harvest time included external attributes (weight and height of fruit, infructescence and crown and internal quality attributes (total soluble solids, pH, translucent flesh. Results showed that the heterogeneity in fruit weight was a consequence of the heterogeneity in vigor of the plants at the moment of flower induction; that effect was mainly on the infructescence weight and less or not on the crown weight. The association between plant vigor variates at flower induction and the internal quality attributes of the fruit were poor and/or not consistent across experiments. The weight of the slips (side shoots, explained part of the heterogeneity in fruit weight, infructescence weight and fruit height in cv. Sugarloaf. Possibilities for reducing the variation in fruit quality by precise cultural practices are discussed.

  15. Quality control results of the drift tubes for the ATLAS MDT-BIS chambers

    International Nuclear Information System (INIS)

    Alexopoulos, T.; Avramidou, R.; Dris, M.; Filippas, T.A.; Gazis, E.N.; Katsoufis, E.; Maltezos, S.; Savva, P.; Tsipolitis, G.; Tzamariudaki, E.

    2006-01-01

    ATLAS (A Toroidal LHC ApparatuS) is a general purpose experiment, which will start its operation at the Large Hadron Collider (LHC) at CERN in 2007. The ATLAS detector is designed to study the products of proton-proton collisions at c.m.s. energies of up to 14 TeV. Three Greek Universities have taken the responsibility to construct 112 BIS-MDT (Barrel Inner Small) chambers using 29 000 drift tubes of 170 cm length and 3 cm diameter that have been quality tested before assembly. This work describes the Quality Assurance and Quality Control (QA Q C) procedures for the drift tubes, followed at the High Energy Physics Laboratory of the National Technical University of Athens, while emphasis is given on the obtained results for the above mentioned number of tubes

  16. Assessment of compliance costs resulting from implementation of the proposed Great Lakes water quality guidance

    International Nuclear Information System (INIS)

    Fenner, K.; Podar, M.; Snyder, B.

    1993-01-01

    The primary purpose of the study was to develop an estimate of the incremental cost to direct dischargers resulting from the implementation of the proposed Great Lakes Water Quality Guidance (GLWQG). This estimate reflects the incremental cost of complying with permit requirements developed using the Implementation Procedures and water quality criteria proposed in the GLWQG versus permit requirements based on existing State water quality standards. Two secondary analyses were also performed, one to develop a preliminary estimate of the costs that would be incurred by indirect dischargers to publicly owned treatment works (POTWs), and another to evaluate the cost-effectiveness of the GLWQG. Finally, several sensitivity analyses were performed to evaluate the impact of several major assumptions on the estimated compliance costs. To estimate compliance costs, permit limitations and conditions based on existing State water quality standards were compared to water quality-based limitations and conditions based on the proposed GLWQG criteria and Implementation Procedures for a sample of plants. The control measures needed to comply with the proposed GLWQG-based effluent limitations were evaluated. Individual plant compliance costs were estimated for these control measures based on information on treatment technology and cost analyses available in the literature. An overall compliance cost was projected from the sample based on statistical methods

  17. Marital quality and diabetes: results from the Health and Retirement Study.

    Science.gov (United States)

    Whisman, Mark A; Li, Angela; Sbarra, David A; Raison, Charles L

    2014-08-01

    Poor marital quality is associated with many different indicators of poor health, including immunologic and metabolic responses that have relevance for distal disease outcomes such as diabetes. We conducted this study to evaluate whether poor marital quality was associated with the prevalence of diabetes in a population-based sample of Americans over the age of 50. Participants were married adults from the 2006 (N = 3,898) and 2008 (N = 3,452) waves of the Health and Retirement Study. Participants completed an interview and a self-report questionnaire, and current use of diabetes medication and glycosylated hemoglobin obtained from blood spot samples were used to index diabetes status. Marital quality was assessed with items regarding perceived frequency of positive and negative exchanges with partner. Decreasing frequency of positive exchanges and increasing frequency of negative exchanges with one's spouse were associated with higher prevalence of diabetes among men, but not women at both waves; gender significantly moderated the associations between partner exchanges and diabetes status for the 2006 data. The association between frequency of partner exchanges and diabetes status generally remained significant in men after accounting for demographic characteristics and other risk factors (obesity, hypertension, low physical activity). Poor marital quality as operationalized by rates of positive and negative partner exchanges was associated with increased prevalence of diabetes in men. These results are consistent with prior work on marriage and health, and suggest that poor marital quality may be a unique risk factor for diabetes.

  18. Results of Use of WHO Global Salm-Surv External Quality Assurance System for Antimicrobial Susceptibility Testing of Salmonella Isolates from 2000 to 2007

    DEFF Research Database (Denmark)

    Hendriksen, Rene S.; Seyfarth, Anne Mette; Jensen, Arne Bent

    2009-01-01

    laboratories in 102 countries participated in at least one EQAS iteration. A large number of laboratories reported results for the E. coli ATCC 25922 reference strain which were outside the quality control ranges. Critical deviations for susceptibility testing of the Salmonella isolates varied from 4% in 2000......An international External Quality Assurance System (EQAS) for antimicrobial susceptibility testing of Salmonella was initiated in 2000 by the World Health Organization (WHO) Global Salm-Surv in order to enhance the capacities of national reference laboratories to obtain reliable data....... In particular, further training and dissemination of information on quality control, appropriate interpretive criteria (breakpoints), and harmonization of the methodology worldwide through WHO Global Salm-Surv and other programs will contribute to the generation of comparable and reliable antimicrobial...

  19. Evaluation of the air quality in the metropolitan region of Belo Horizonte, Minas Gerais: first results

    Energy Technology Data Exchange (ETDEWEB)

    Moura, Igor Felipe Silva, E-mail: igorfelipedx@yahoo.com.br [Universidade Federal de Minas Gerais (DEN/UFMG), Belo Horizonte, MG (Brazil). Departamento de Engenharia Nuclear; Cruz, Ananda Borjaille; Fonseca, Raquel Luiza M.; Barreto, Alberto Avellar; Menezes, Maria Angela de B.C., E-mail: abc@cdtn.br, E-mail: menezes@cdtn.br, E-mail: aab@cdtn.br [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN/CNEN-MG), Belo Horizonte (Brazil)

    2015-07-01

    The Metropolitan Region of Belo Horizonte presents many industrial activities related to several industries, mainly mining activities, besides the high population concentration, which also contributes to several industrial typologies due to the existence of qualified work and to the vicinity of a future consumer market. This concentration of the population also implies in a great number of vehicles and, consequently, in big traffic jams. The particulate material is one of the pollutants which cause higher environmental risk and it is a mixture of solid and liquid particles in the air which form aerosols. These aerosols, which contain organic and inorganic substances, vary of size, form, composition and origin. In order to characterize the quality of the airborne particulate matter and identify the pollutant sources, a research is being developing in the Metropolitan Region of Belo Horizonte. This paper is focused on presenting the methodology of sampling, determination of concentration of particulates, elemental concentration analysis by k{sub 0}-Neutron Activation method and meteorological analysis, related to two sampling points, one at CDTN/CNEN and other at UFMG. (author)

  20. Evaluation of the air quality in the metropolitan region of Belo Horizonte, Minas Gerais: first results

    International Nuclear Information System (INIS)

    Moura, Igor Felipe Silva

    2015-01-01

    The Metropolitan Region of Belo Horizonte presents many industrial activities related to several industries, mainly mining activities, besides the high population concentration, which also contributes to several industrial typologies due to the existence of qualified work and to the vicinity of a future consumer market. This concentration of the population also implies in a great number of vehicles and, consequently, in big traffic jams. The particulate material is one of the pollutants which cause higher environmental risk and it is a mixture of solid and liquid particles in the air which form aerosols. These aerosols, which contain organic and inorganic substances, vary of size, form, composition and origin. In order to characterize the quality of the airborne particulate matter and identify the pollutant sources, a research is being developing in the Metropolitan Region of Belo Horizonte. This paper is focused on presenting the methodology of sampling, determination of concentration of particulates, elemental concentration analysis by k 0 -Neutron Activation method and meteorological analysis, related to two sampling points, one at CDTN/CNEN and other at UFMG. (author)

  1. Study of alternatives for improving air quality in the town of Itagui, the result of an examination under the scheme of analysis Environment Energy Economy with the MARKAL model and evaluation of goals

    International Nuclear Information System (INIS)

    Builes J, Luis A; Franco M, Cristina; Rave Claudia C

    2008-01-01

    For the integrated analysis and assessment of the air quality improvement guidelines in the Aburra Valley region and its municipality Itagui, it is used a multi-period optimization model Markal for an Energy-Environment-Economy scenario analysis on industry and transport sector and, a Targets evaluation methodology for policy assessment on air quality, environmental noise and morbidity. The methodological approach offers the possibility to integrate different variables and decisions to analyze this very complex problem, review different technological scenarios and to analyze their relationships with land use policies among others. The results provide a more integrated panorama of the air quality problematic to policy design and assessment including externalises indicators. The proposed methodology is replicable in other municipalities of the region.

  2. Incorporating Variational Local Analysis and Prediction System (vLAPS) Analyses with Nudging Data Assimilation: Methodology and Initial Results

    Science.gov (United States)

    2017-09-01

    in the hybrid scheme. They conclude that in the Lorenz model they investigated, the hybrid scheme cannot result in errors that are simultaneously ...centered on the analysis time. Note that the spatial and temporal refinement of the analyses are taking place simultaneously (i.e., the first analysis...of a strong capping inversion and then a deep elevated mixed layer. At 1800 UTC (Fig. 5b), daytime heating along with the formation of a convective

  3. Evaluation of late effects, esthetic results and quality of life after conservative treatment of breast cancer?

    International Nuclear Information System (INIS)

    Geffrelot, J.; Toudic-Emily, F.; Delozier, T.; Switsers, O.; Allouache, D.; Delcambre, C.; Segura, C.; Levy, C.; Dupont, M.; Joly, F.

    2009-01-01

    Purpose: to evaluate the delayed toxicity of two patterns of adjuvant radiotherapy including a breast irradiation, at the dose of 48 Gy in 20 seances and five weeks or 57.60 Gy in 24 seances and six weeks in case of majored factors of local recurrence risk. The secondary objective were the auto evaluation by the patient of the esthetic result and the influence of this last one on the quality of life. Conclusion: the delayed toxicity was dominated by the fibrosis low to moderated one, without any significant difference between the doses of 48 Gy and 57.60 Gy. The esthetic result evaluated by the patient, globally good, seemed however, damaged with the last pattern. A bad esthetic result, without affected the global quality of life was associated to more specific breast symptoms and damaged the perception of the body image. (N.C.)

  4. [Analysis of the results of the SEIMC External Quality Control Program. Year 2011].

    Science.gov (United States)

    Ruiz de Gopegui Bordes, Enrique; Guna Serrano, M del Remedio; Orta Mira, Nieves; Ovies, María Rosario; Poveda, Marta; Gimeno Cardona, Concepción

    2013-02-01

    The External Quality Control Program of the Spanish Society of Infectious Diseases and Clinical Microbiology (Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica [SEIMC]) includes controls for bacteriology, serology, mycology, parasitology, mycobacteria, virology, and molecular microbiology. This article presents the most relevant conclusions and lessons from the 2011 controls. Overall, the results obtained in 2011 confirm the excellent skill and good technical standards found in previous years. Nevertheless, erroneous results can be obtained in any laboratory and in clinically relevant determinations. The results of this program highlight the need to implement both internal and external controls, such as those offered by the SEIMC program, in order to ensure maximal quality of microbiological tests. Copyright © 2013 Elsevier España, S.L. All rights reserved.

  5. [Analysis of the results of the SEIMC External Quality Control Program. Year 2012].

    Science.gov (United States)

    de Gopegui Bordes, Enrique Ruiz; Guna Serrano, M del Remedio; Orta Mira, Nieves; Ovies, María Rosario; Poveda, Marta; Gimeno Cardona, Concepción

    2014-02-01

    The External Quality Control Program of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) include controls for bacteriology, serology, mycology, parasitology, mycobacteria, virology and molecular microbiology. This article presents the most relevant conclusions and lessons from the 2012 controls. As a whole, the results obtained in 2012 confirm the excellent skill and good technical standards found in previous editions. However, erroneous results can be obtained in any laboratory and in clinically relevant determinations. Once again, the results of this program highlighted the need to implement both internal and external controls in order to assure the maximal quality of the microbiological tests. Copyright © 2014 Elsevier España, S.L. All rights reserved.

  6. [Analysis of the results of the SEIMC External Quality Control Program. Year 2014].

    Science.gov (United States)

    Gopegui Bordes, Enrique Ruiz de; Guna Serrano, M Del Remedio; Orta Mira, Nieves; Medina González, Rafael; Rosario Ovies, María; Poveda, Marta; Gimeno Cardona, Concepción

    2016-07-01

    The External Quality Control Program of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) include controls for bacteriology, serology, mycology, parasitology, mycobacteria, virology and molecular microbiology. This article presents the most relevant conclusions and lessons from the 2014 controls. As a whole, the results obtained in 2014 confirm the excellent skill and good technical standards found in previous editions. However, erroneous results can be obtained in any laboratory and in clinically relevant determinations. Once again, the results of the SEIMC program highlighted the need to implement both internal and external controls in order to assure the maximal quality of the microbiological tests. Copyright © 2016 Elsevier España, S.L.U. All rights reserved.

  7. [Analysis of the results of the SEIMC External Quality Control Program. Year 2009].

    Science.gov (United States)

    de Gopegui Bordes, Enrique Ruiz; del Remedio Guna Serrano, M; Orta Mira, Nieves; Ovies, María; Poveda, Marta; Gimeno Cardona, Concepción; Pérez, José L

    2011-03-01

    The External Quality Control Program of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) includes controls for bacteriology, serology, mycology, parasitology, mycobacteria, virology and molecular microbiology. In this article, the most important conclusions and lessons from the 2009 controls are presented. As a whole, the results obtained in 2009 confirm the excellent skill and good technical standards found in previous editions. However, erroneous results can be obtained in any laboratory and in clinically relevant determinations. The results of this program highlight the need to implement both internal and external controls in order to ensure maximal quality of microbiological tests. Copyright © 2011 Elsevier España S.L. All rights reserved.

  8. Towards an Operational Use of Geophysics for Archaeology in Henan (China: Methodological Approach and Results in Kaifeng

    Directory of Open Access Journals (Sweden)

    Nicola Masini

    2017-08-01

    Full Text Available One of the major issues in buried archeological sites especially if characterized by intense human activity, complex structures, and several constructive phases, is: to what depth conduct the excavation? The answer depends on a number of factors, among these one of the most important is the a priori and reliable knowledge of what the subsoil can preserve. To this end, geophysics (if used in strong synergy with archaeological research can help in the planning of time, depth, and modes of excavation also when the physical characteristics of the remains and their matrix are not ideal for archaeo-geophysical applications. This is the case of a great part of the archaeological sites in Henan, the cradle of the most important cultures in China and the seat of several capitals for more than two millennia. There, the high depth of buried remains covered by alluvial deposits and the building materials, mainly made by rammed earth, did not favor the use of geophysics. In this paper, we present and discuss the GPR and ERT prospection we conducted in Kaifeng (Henan, China, nearby a gate of the city walls dated to the Northern Song Dynasty. The integration of GPR and ERT provided useful information for the identification and characterization of archaeological remains buried at different depths. Actually, each geophysical technique, GPR frequency (used for the data acquisition as well as each way to analyze and visualize the results (from radargrams to time slice only provided partial information of little use if alone. The integration of the diverse techniques, data processing and visualization enabled us to optimize the penetration capability, the resolution for the detection of archaeological features and their interpretation. Finally, the results obtained from the GPR and ERT surveys were correlated with archaeological stratigraphy, available nearby the investigated area. This enabled us to further improve the interpretation of results from GPR and ERT

  9. The LBB methodology application results performed on the safety related piping of NPP V-1 in Jaslovske Bohunice

    Energy Technology Data Exchange (ETDEWEB)

    Kupca, L.; Beno, P. [Nuclear Power Plants Research Institute, Trnava (Slovakia)

    1997-04-01

    A broad overview of the leak before break (LBB) application to the Slovakian V-1 nuclear power plant is presented in the paper. LBB was applied to the primary cooling circuit and surge lines of both WWER 440 type units, and also used to assess the integrity of safety related piping in the feed water and main steam systems. Experiments and calculations performed included analyses of stresses, material mechanical properties, corrosion, fatigue damage, stability of heavy component supports, water hammer, and leak rates. A list of analysis results and recommendations are included in the paper.

  10. Double contrast barium enema: technique, indications, results and limitations of a conventional imaging methodology in the MDCT virtual endoscopy era.

    Science.gov (United States)

    Rollandi, Gian Andrea; Biscaldi, Ennio; DeCicco, Enzo

    2007-03-01

    The double contrast barium enema of the colon continues to be a diffused conventional radiological technique and allows for the diagnosis of neoplastic and inflammatory pathology. After the '70s, a massive initiative is undertaken to simplify, perfect and encode the method of the double contrast barium enema: Altaras from Germany, Miller from USA and Cittadini from Italy are responsible for the perfection of this technique in the last 30 years. The tailored patient preparation, a perfect technique of execution and a precise radiological documentation are essentials steps to obtain a reliable examination. The main limit of double contrast enema is that it considers the pathology only from the mucosal surface. In neoplastic pathology evaluation the main limit is the "T" parameter staging, but more limited are the "N" and "M" parameters evaluation. Today the double contrast technique continues to be a refined, sensitive and specific diagnostic method, moreover, diagnostic results cannot compete with the new CT multislice techniques (CT-enteroclysis and virtual colonoscopy) which can examine both the lumen and the wall of the colon. The double contrast is a cheap and simple examination but in the next future is predictably a progressive substitution of conventional radiology from new multislice techniques, because the cross sectional imaging is more frequently able to detect causes of the symptoms whether resulting both from colonic or non colonic origin.

  11. Double contrast barium enema: Technique, indications, results and limitations of a conventional imaging methodology in the MDCT virtual endoscopy era

    International Nuclear Information System (INIS)

    Rollandi, Gian Andrea; Biscaldi, Ennio; DeCicco, Enzo

    2007-01-01

    The double contrast barium enema of the colon continues to be a diffused conventional radiological technique and allows for the diagnosis of neoplastic and inflammatory pathology. After the '70s, a massive initiative is undertaken to simplify, perfect and encode the method of the double contrast barium enema: Altaras from Germany, Miller from USA and Cittadini from Italy are responsible for the perfection of this technique in the last 30 years. The tailored patient preparation, a perfect technique of execution and a precise radiological documentation are essentials steps to obtain a reliable examination. The main limit of double contrast enema is that it considers the pathology only from the mucosal surface. In neoplastic pathology evaluation the main limit is the 'T' parameter staging, but more limited are the 'N' and 'M' parameters evaluation. Today the double contrast technique continues to be a refined, sensitive and specific diagnostic method, moreover, diagnostic results cannot compete with the new CT multislice techniques (CT-enteroclysis and virtual colonoscopy) which can examine both the lumen and the wall of the colon. The double contrast is a cheap and simple examination but in the next future is predictably a progressive substitution of conventional radiology from new multislice techniques, because the cross sectional imaging is more frequently able to detect causes of the symptoms whether resulting both from colonic or non colonic origin

  12. Analytical quality control in environmental analysis - Recent results and future trends of the IAEA's analytical quality control programme

    Energy Technology Data Exchange (ETDEWEB)

    Suschny, O; Heinonen, J

    1973-12-01

    The significance of analytical results depends critically on the degree of their reliability, an assessment of this reliability is indispensable if the results are to have any meaning at all. Environmental radionuclide analysis is a relatively new analytical field in which new methods are continuously being developed and into which many new laboratories have entered during the last ten to fifteen years. The scarcity of routine methods and the lack of experience of the new laboratories have made the need for the assessment of the reliability of results particularly urgent in this field. The IAEA, since 1962, has provided assistance to its member states by making available to their laboratories analytical quality control services in the form of standard samples, reference materials and the organization of analytical intercomparisons. The scope of this programme has increased over the years and now includes, in addition to environmental radionuclides, non-radioactive environmental contaminants which may be analysed by nuclear methods, materials for forensic neutron activation analysis, bioassay materials and nuclear fuel. The results obtained in recent intercomparisons demonstrate the continued need for these services. (author)

  13. Non-pharmacological sleep interventions for youth with chronic health conditions: a critical review of the methodological quality of the evidence.

    Science.gov (United States)

    Brown, Cary A; Kuo, Melissa; Phillips, Leah; Berry, Robyn; Tan, Maria

    2013-07-01

    Restorative sleep is clearly linked with well-being in youth with chronic health conditions. This review addresses the methodological quality of non-pharmacological sleep intervention (NPSI) research for youth with chronic health conditions. The Guidelines for Critical Review (GCR) and the Effective Public Health Practice Project Quality Assessment Tool (EPHPP) were used in the review. The search yielded 31 behavioural and 10 non-behavioural NPSI for review. Most studies had less than 10 participants. Autism spectrum disorders, attention deficit/hyperactivity disorders, down syndrome, intellectual disabilities, and visual impairments were the conditions that most studies focused upon. The global EPHPP scores indicated most reviewed studies were of weak quality. Only 7 studies were rated as moderate, none were strong. Studies rated as weak quality frequently had recruitment issues; non-blinded participants/parents and/or researchers; and used outcome measures without sound psychometric properties. Little conclusive evidence exists for NPSIs in this population. However, NPSIs are widely used and these preliminary studies demonstrate promising outcomes. There have not been any published reports of negative outcomes that would preclude application of the different NPSIs on a case-by-case basis guided by clinical judgement. These findings support the need for more rigorous, applied research. • Methodological Quality of Sleep Research • Disordered sleep (DS) in youth with chronic health conditions is pervasive and is important to rehabilitation therapists because DS contributes to significant functional problems across psychological, physical and emotional domains. • Rehabilitation therapists and other healthcare providers receive little education about disordered sleep and are largely unaware of the range of assessment and non-pharmacological intervention strategies that exist. An evidence-based website of pediatric sleep resources can be found at http

  14. Vestibular schwannomas: clinical results and quality of life after microsurgery or gamma knife radiosurgery.

    Science.gov (United States)

    Myrseth, Erling; Møller, Per; Pedersen, Paal-Henning; Vassbotn, Flemming S; Wentzel-Larsen, Tore; Lund-Johansen, Morten

    2005-05-01

    The aim of the present study was to evaluate the overall treatment efficacy (tumor control, facial nerve function, complications) and quality of life for patients treated primarily for unilateral vestibular schwannomas of 30 mm or less, either by microsurgery or by gamma knife (GK) radiosurgery. The results for the two treatment groups are compared with each other, with main emphasis on the long-term quality of life. This is a retrospective study of 189 consecutive patients, 86 treated by microsurgery and 103 by gamma knife. The mean observation time was 5.9 years. All patients had a magnetic resonance imaging scan and clinical evaluation performed toward the end of the study. To evaluate the quality of life, we used two standardized questionnaires, the Glasgow Benefit Inventory and Short-Form 36. The questionnaires were sent to the 168 living patients. The reply rate was 83.3%. A total of 79.8% of the patients in the microsurgery group and 94.8% of the GK patients had a good facial nerve function (House-Brackmann Grade 1-2). Hearing was usually lost after microsurgery, whereas the GK patients had preserved hearing, which often became reduced over the years after the treatment. The treatment efficacy, defined as no need for additional treatment, was similar for the two treatment modalities. Quality of life was reduced compared with normative data, being most reduced in the microsurgery group. Some of the quality of life questions showed an association with facial nerve function and sex. Posttreatment facial nerve function, hearing, complication rates, and quality of life were all significantly in favor of GK radiosurgery.

  15. Living probabilistic safety assessment of French 1300 MWe PWR nuclear power plant unit: methodology, results and teaching

    International Nuclear Information System (INIS)

    Dubreuil Chambardel, A.; Villemeur, A.; Berger, J.P.; Moroni, J.M.

    1991-02-01

    Launched in 1986 by Electricite de France, the Probabilistic Safety Assessment of a French 1300 MWe Pressurized Water Reactor (called PSA 1300) was completed in 1989. The first objective was to assess the annual core damage frequency by identifying all the accident scenarii likely to contribute significantly to this frequency. The second objective of the study was to provide an automated computerized tool (software) for updating the assessment - in order to take new data and knowledge into account - and for performing numerous sensitivity studies easily. Its scope and characteristics render this study unique. Indeed, it required an effort amounting to 50 engineer-years. The results and the first lessons are presented in this paper. The PSA 1300 teachings will be extensively used for the design and operation of existing or future French nuclear power reactors

  16. Methodological approaches to conducting pilot and proof tests on reverse-osmosis systems: Results of comparative studies

    Science.gov (United States)

    Panteleev, A. A.; Bobinkin, V. V.; Larionov, S. Yu.; Ryabchikov, B. E.; Smirnov, V. B.; Shapovalov, D. A.

    2017-10-01

    When designing large-scale water-treatment plants based on reverse-osmosis systems, it is proposed to conduct experimental-industrial or pilot tests for validated simulation of the operation of the equipment. It is shown that such tests allow establishing efficient operating conditions and characteristics of the plant under design. It is proposed to conduct pilot tests of the reverse-osmosis systems on pilot membrane plants (PMPs) and test membrane plants (TMPs). The results of a comparative experimental study of pilot and test membrane plants are exemplified by simulating the operating parameters of the membrane elements of an industrial plant. It is concluded that the reliability of the data obtained on the TMP may not be sufficient to design industrial water-treatment plants, while the PMPs are capable of providing reliable data that can be used for full-scale simulation of the operation of industrial reverse-osmosis systems. The test membrane plants allow simulation of the operating conditions of individual industrial plant systems; therefore, potential areas of their application are shown. A method for numerical calculation and experimental determination of the true selectivity and the salt passage are proposed. An expression has been derived that describes the functional dependence between the observed and true salt passage. The results of the experiments conducted on a test membrane plant to determine the true value of the salt passage of a reverse-osmosis membrane are exemplified by magnesium sulfate solution at different initial operating parameters. It is shown that the initial content of a particular solution component has a significant effect on the change in the true salt passage of the membrane.

  17. How do the methodological choices of your climate change study affect your results? A hydrologic case study across the Pacific Northwest

    Science.gov (United States)

    Chegwidden, O.; Nijssen, B.; Rupp, D. E.; Kao, S. C.; Clark, M. P.

    2017-12-01

    We describe results from a large hydrologic climate change dataset developed across the Pacific Northwestern United States and discuss how the analysis of those results can be seen as a framework for other large hydrologic ensemble investigations. This investigation will better inform future modeling efforts and large ensemble analyses across domains within and beyond the Pacific Northwest. Using outputs from the Coupled Model Intercomparison Project Phase 5 (CMIP5), we provide projections of hydrologic change for the domain through the end of the 21st century. The dataset is based upon permutations of four methodological choices: (1) ten global climate models (2) two representative concentration pathways (3) three meteorological downscaling methods and (4) four unique hydrologic model set-ups (three of which entail the same hydrologic model using independently calibrated parameter sets). All simulations were conducted across the Columbia River Basin and Pacific coastal drainages at a 1/16th ( 6 km) resolution and at a daily timestep. In total, the 172 distinct simulations offer an updated, comprehensive view of climate change projections through the end of the 21st century. The results consist of routed streamflow at 400 sites throughout the domain as well as distributed spatial fields of relevant hydrologic variables like snow water equivalent and soil moisture. In this presentation, we discuss the level of agreement with previous hydrologic projections for the study area and how these projections differ with specific methodological choices. By controlling for some methodological choices we can show how each choice affects key climatic change metrics. We discuss how the spread in results varies across hydroclimatic regimes. We will use this large dataset as a case study for distilling a wide range of hydroclimatological projections into useful climate change assessments.

  18. Effect of Some Egg Quality Traits on Hatching Results in Brown Pure Lines

    Directory of Open Access Journals (Sweden)

    İsmail Durmuş

    2016-09-01

    Full Text Available This study was conducted to determine the influence of eggshell thickness, albumen height, yolk height and haugh unit on hatching results. A total of 746 eggs, which were obtained and evaluated for egg quality parameters from 100 brown pure line hens of 42 weeks of age, were used. Eggs were collected from each hen for 12 days and individual incubation was carried out. Eggs were grouped based on quality parameters and evaluated accordingly. The findings suggested that hatchability, hatchability of fertile eggs, early, mid and late embryonic mortality did not differ in terms of haugh unit, albumen height, eggshell thickness and yolk height groups. However, early embryonic mortality was found different between the yolk height groups. No relationship was determined among albumen height, haugh unit, eggshell thickness and hatching results. There was no relation between yolk height and hatchability of fertile eggs, hatchability, mid and late embryonic mortalities but was a positive correlation with early embryonic mortality. The results of the present study demonstrate that egg quality parameters studied here had no influence on hatching results except that early embryonic mortality increased with the yolk height.

  19. Large-Scale Atmospheric Circulation Patterns Associated with Temperature Extremes as a Basis for Model Evaluation: Methodological Overview and Results

    Science.gov (United States)

    Loikith, P. C.; Broccoli, A. J.; Waliser, D. E.; Lintner, B. R.; Neelin, J. D.

    2015-12-01

    Anomalous large-scale circulation patterns often play a key role in the occurrence of temperature extremes. For example, large-scale circulation can drive horizontal temperature advection or influence local processes that lead to extreme temperatures, such as by inhibiting moderating sea breezes, promoting downslope adiabatic warming, and affecting the development of cloud cover. Additionally, large-scale circulation can influence the shape of temperature distribution tails, with important implications for the magnitude of future changes in extremes. As a result of the prominent role these patterns play in the occurrence and character of extremes, the way in which temperature extremes change in the future will be highly influenced by if and how these patterns change. It is therefore critical to identify and understand the key patterns associated with extremes at local to regional scales in the current climate and to use this foundation as a target for climate model validation. This presentation provides an overview of recent and ongoing work aimed at developing and applying novel approaches to identifying and describing the large-scale circulation patterns associated with temperature extremes in observations and using this foundation to evaluate state-of-the-art global and regional climate models. Emphasis is given to anomalies in sea level pressure and 500 hPa geopotential height over North America using several methods to identify circulation patterns, including self-organizing maps and composite analysis. Overall, evaluation results suggest that models are able to reproduce observed patterns associated with temperature extremes with reasonable fidelity in many cases. Model skill is often highest when and where synoptic-scale processes are the dominant mechanisms for extremes, and lower where sub-grid scale processes (such as those related to topography) are important. Where model skill in reproducing these patterns is high, it can be inferred that extremes are

  20. Quality of Work Life: Theoretical and Methodological Problems, and Presentation of a New Model and Measuring Instrument

    Science.gov (United States)

    Martel, Jean-Pierre; Dupuis, Gilles

    2006-01-01

    Purpose: Ever since the concept of Quality of Work Life (QWL) was first used over 30 years ago, a range of definitions and theoretical constructs have succeeded each other with the aim of mitigating the many problems facing the concept. A historical overview of the concept of QWL is presented here. Given the lack of consensus concerning the…

  1. 40 CFR Appendix A to Part 132 - Great Lakes Water Quality Initiative Methodologies for Development of Aquatic Life Criteria and...

    Science.gov (United States)

    2010-07-01

    .... If the acute toxicity of the material to aquatic animals has been shown to be related to a water... material to aquatic animals has been shown to be related to a water quality characteristic such as hardness... a material in the water column to which an aquatic community can be exposed briefly without...

  2. Methodology for calculating perception of the user experience of the quality of monitored integrated telecommunications operator services

    NARCIS (Netherlands)

    2011-01-01

    The invention relates to a method for calculating perception of the user experience of the quality of monitored integrated telecommunications operator services. For this purpose, data from the monitoring of user services is used, along with questionnaires previously completed by a representative

  3. [Analysis of the results of the SEIMC External Quality Control Program, 2007].

    Science.gov (United States)

    Guna Serrano, María del Remedio; Orta Mira, Nieves; Ovies, María; Gimeno Cardona, Concepción; Pérez, José L

    2008-11-01

    The External Quality Control Program of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) includes controls for bacteriology, serology, mycology, parasitology, mycobacteria, virology and molecular microbiology. This article presents the most important conclusions and lessons drawn from the 2007 controls. As a whole, the results obtained in 2007 confirm the excellent skill and good technical standards found in previous years. However, erroneous results can be obtained in any laboratory and in clinically relevant determinations. A few deviations were observed in some controls, calling for critical reflection. Once again, the results of this program highlighted the need to complement internal with external controls, such as those offered by the SEIMC program.

  4. Water quality changes as a result of coalbed methane development in a Rocky mountain watershed

    Energy Technology Data Exchange (ETDEWEB)

    Wang, X.; Melesse, A.M.; McClain, M.E.; Yang, W. [Tarleton State University, Stephenville, TX (USA)

    2007-12-15

    Coalbed methane (CBM) development raises serious environmental concerns. In response, concerted efforts have been made to collect chemistry, salinity, and sodicity data on CBM produced water. However, little information on changes of stream water quality resulting from directly and/or indirectly received CBM produced water is available in the literature. The objective of this study was to examine changes in stream water quality, particularly sodicity and salinity, due to CBM development in the Powder River watershed, which is located in the Rocky Mountain Region and traverses the states of Wyoming and Montana. To this end, a retrospective analysis of water quality trends and patterns was conducted using data collected from as early as 1946 up to and including 2002 at four U.S. Geological Survey gauging stations along the Powder River. Trend analysis was conducted using linear regression and Seasonal Kendall tests, whereas, Tukey's test for multiple comparisons was used to detect changes in the spatial pattern. The results indicated that the CBM development adversely affected the water quality in the Powder River. First, the development elevated the stream sodicity, as indicated by a significant increase trend of the sodium adsorption ratio. Second, the development tended to shrink the water quality differences among the three downstream stations but to widen the differences between these stations and the farthest upstream station. In contrast, the development had only a minor influence on stream salinity. Hence, the CBM development is likely an important factor that can be managed to lower the stream sodicity. The management may need to take into account that the effects of the CBMdevelopment were different from one location to another along the Powder River.

  5. The BioREGIO Carpathians project: aims, methodology and results from the “Continuity and Connectivity” analysis

    Directory of Open Access Journals (Sweden)

    Filippo Favilli

    2015-07-01

    Full Text Available BioREGIO Carpathians is a transnational cooperation project, co-financed under the second call of the EU South East Europe Transnational Cooperation Programme, priority area “Protection and Improvement of the Environment”. BioREGIO Carpathians run for three years (2011–2013 and is a flagship project for the Carpathian Convention (article four dealing with landscape and biological diversity, its Biodiversity Protocol and the Biodiversity Working Group. The project is built on the conservation, restoration and valorisation of the Carpathians ecological continuum to enable large herbivores and carnivores to live in coexistence with modern society. The Carpathian countries are expecting a massive pressure to modernize and extend their road infrastructures. If not considering the requirements of ecological network, this run-to-development will enhance landscape fragmentation, limit dispersal and genetic exchange of wildlife species. BioREGIO applied a multi-disciplinary approach (physical, legal and socio-economic in order to identify the most influencing barriers regarding connectivity throughout the Carpathians. Using two ArcGIS 10.0 tools in a three-step approach and a series of site visits, the continuity and connectivity analysis identified not only physical barriers but also legal aspects and socio-economic behaviour that are influencing ecological connectivity and playing a major role to conserve wildlife population. The investigation on the ground together with local experts and stakeholders enabled the adaptation of the GIS results and the development of feasible solutions to overcome the detected barriers with recommended priorities for implementing appropriate measurements to maintain connectivity and to sustain large carnivores, herbivores and biodiversity in the Carpathians.

  6. Radiation resistance of elastomeric O-rings in mixed neutron and gamma fields: Testing methodology and experimental results

    Science.gov (United States)

    Zenoni, A.; Bignotti, F.; Donzella, A.; Donzella, G.; Ferrari, M.; Pandini, S.; Andrighetto, A.; Ballan, M.; Corradetti, S.; Manzolaro, M.; Monetti, A.; Rossignoli, M.; Scarpa, D.; Alloni, D.; Prata, M.; Salvini, A.; Zelaschi, F.

    2017-11-01

    Materials and components employed in the presence of intense neutron and gamma fields are expected to absorb high dose levels that may induce deep modifications of their physical and mechanical properties, possibly causing loss of their function. A protocol for irradiating elastomeric materials in reactor mixed neutron and gamma fields and for testing the evolution of their main mechanical and physical properties with absorbed dose has been developed. Four elastomeric compounds used for vacuum O-rings, one fluoroelastomer polymer (FPM) based and three ethylene propylene diene monomer rubber (EPDM) based, presently available on the market have been selected for the test. One EPDM is rated as radiation resistant in gamma fields, while the other elastomers are general purpose products. Particular care has been devoted to dosimetry calculations, since absorbed dose in neutron fields, unlike pure gamma fields, is strongly dependent on the material composition and, in particular, on the hydrogen content. The products have been tested up to about 2 MGy absorbed dose. The FPM based elastomer, in spite of its lower dose absorption in fast neutron fields, features the largest variations of properties, with a dramatic increase in stiffness and brittleness. Out of the three EPDM based compounds, one shows large and rapid changes in the main mechanical properties, whereas the other two feature more stable behaviors. The performance of the EPDM rated as radiation resistant in pure gamma fields does not appear significantly better than that of the standard product. The predictive capability of the accelerated irradiation tests performed as well as the applicable concepts of threshold of radiation damage is discussed in view of the use of the examined products in the selective production of exotic species facility, now under construction at the Legnaro National Laboratories of the Italian Istituto Nazionale di Fisica Nucleare. It results that a careful account of dose rate effects

  7. [Analysis of the results of the SEIMC External Quality Control Program. Year 2008].

    Science.gov (United States)

    Serrano, María del Remedio Guna; Mira, Nieves Orta; de Gopegui, Enrique Ruiz; Ovies, María Rosario; Cardona, Concepción Gimeno; Pérez, José L

    2010-01-01

    The External Quality Control Program of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) include controls for bacteriology, serology, mycology, parasitology, mycobacteria and virology. This article present the most relevant conclusions and lessons from the 2008 controls. As a whole, the results obtained in 2008 confirm the excellent skill and good technical standards of the microbiology laboratories in Spain found in previous editions. However, a few deviations can be obtained in any laboratory, even in clinically relevant determinations. Once again, the results of this program highlighted the need to implement both internal an external controls in order to assure the maximal quality of the microbiological tests. 2010 Elsevier España S.L. All rights reserved.

  8. Assembly and Quality Control of the LHC Cryostats at CERN Motivations, Means, Results and Lessons Learnt

    CERN Document Server

    Poncet, A; Parma, V; Strubin, P; Tock, JP; Tommasini, D

    2007-01-01

    In 2001, the project management decided to perform at CERN the final assembly of the LHC superconducting magnets with cryostat parts and cold masses produced by European Industry in large series. This industrial-like production has required a very significant investment in tooling, production facilities, engineering and quality control efforts, in contractual partnership with a consortium of firms. This unusual endeavour of a limited lifetime represented more than 850,000 working hours spanning over five years, the work being done on a result-oriented basis by the contractor. This paper presents the reasons for having conducted this project at CERN, summarizes the work breakdown structure, the production means and methods, the infrastructure specially developed, the tooling, logistics and quality control aspects of the work performed and the results achieved, in analytical form. Finally, the lessons learnt are outlined.

  9. Research and systematization of 'hot' particles in the Semipalatinsk nuclear test site soils - methodology and first results

    International Nuclear Information System (INIS)

    Gorlachev, I.D.; Knyazev, B.B.; Kvochkina, T.N.; Lukashenko, S.N.

    2005-01-01

    . The 'hot' particles search was also based on the difference of 'hot' and soil particles shapes. There are two species of large 'hot' particles: 1. 'hot' particles with regular contours and flowed shapes looked like on the earlier selected 'hot' particles from the first and second fractions of soil samples. 2. 'hot' particles with irregular shape. Preliminary results of the researches are presented in this paper

  10. SOME STATISTICAL RESULTS REGARDING THE EVALUATION OF THE QUALITY OF THE MASTER EDUCATION

    Directory of Open Access Journals (Sweden)

    POPA IRIMIE

    2011-12-01

    Full Text Available The article emphasizes aspects regarding the evaluation of the higher education's quality. In certain countries, the questionnaires regarding quality of the activity of HEIs (Higher Education Institutions are administrated by specialized institutions led by the Ministry of Education or the university associations. The evaluation principles derive from well-known economic and social theories, evolving even evaluation models (see the SERVQUAL model. As a result of the Bologna Treaty (1999, the European Union has the objective to become an international reference concerning the higher education quality and to be more attractive than in the present for students, professors and researchers from other regions of the world. So as to fulfill these objectives ENQA (European Association for Quality Assurance in Higher Education recommends HEIs to include in their development plans regarding quality aspects five principles described in the article. The practical study refers to the results of a questionnaire applied to the master business students from a Romanian university. In order to assess the level of satisfaction of students in relation to the master programme they are involved in, a questionnaire was applied on a sample of 200 such persons. The responses were then analyzed using multidimensional data analysis methods. Out of these, the present research is based on multiple response analysis. In the questionnaire, students were asked to return their level of satisfaction for different aspects related to the educational process they are involved in. The questions were constructed as five-level Likert items. In this way was insured a connection between answers given at each of the questions assessing the quality of the programme. Only 0.2% of the answers given relate to aspects about which the students were not satisfied at all. These answers represent 3.2% of the number of respondents. 30% of the students were slightly satisfied, returning 57 choices

  11. Results of the project on service quality in the eastern region of Spain

    Energy Technology Data Exchange (ETDEWEB)

    Martinez-Canales, J.F.; Alcaide, J. [IBERDROLA (Spain); Cavalle, F.; Romualdo, F. [Universidad Poltecnica de Valencia (Spain)

    1997-12-31

    The most significant results obtained from a study of short time interruptions in the Spanish electrical network and methods to minimise their effects are outlined. The areas covered are: monitoring of the incidence of interruptions and their effects on industrial consumers` facilities; proposed solutions; evaluation of the economic losses to consumers; recommendations on electricity supply quality; and recommendations to consumers on minimising the effects of disturbances in the network. (UK)

  12. Results of a national quality audit programme for radiotherapy centers in Iran

    International Nuclear Information System (INIS)

    Solimanian, A.; Ghafoori, M.

    1998-01-01

    The SSDL of Iran has established a quality audit programme for radiotherapy centers in the country. Most of the radiotherapy departments are now audited annually by the SSDL dosimetry team. During the site visits, beam characteristics of the teletherapy units are determined or tested. This report presents the results of the on-site output measurements conducted during the period 1985-1996 and demonstrates the role of traceability of absorbed dose to water determinations in hospitals to the SSDL standard. (author)

  13. A comparison of controlled self-pollination and open pollination results based on maize grain quality

    Directory of Open Access Journals (Sweden)

    Hanna Sulewska

    2014-05-01

    Full Text Available Maize (Zea mays L. grain endosperm is triploid (3n, of which 2n come from the male (transferred by pollen and only 1n from the female plant, thus a major impact of the male form can be expected on grain quality parameters. A good example of this relationship is the phenomenon of xenia. The aim of this study was to determine the effect of pollen on grain quality. The field experiment was conducted in 2011; seeds were harvested from eight cultivars: Bosman, Blask, Tur, Kozak, Bielik, Smok, SMH 220 and Kresowiak, derived from free pollination and controlled self-pollination of maize. Analyses of nutrient contents and starch content in the grain were conducted in the laboratory. In addition, 1000 grain weight and the hectoliter weight of all grain samples were recorded. The results confirmed differences in grain quality of maize hybrids obtained by self-pollination and by open pollination. Grain of maize plants obtained by open-pollination was characterised by higher contents of N-free extract and starch, and lower protein content. Undertaking further studies on this subject may indicate specific recommendations for agricultural practice, such as mixtures of hybrids with good combining abilities, which will contribute to improved grain quality without additional costs.

  14. Sci-Fri AM: Quality, Safety, and Professional Issues 01: CPQR Technical Quality Control Suite Development including Quality Control Workload Results

    International Nuclear Information System (INIS)

    Malkoske, Kyle; Nielsen, Michelle; Brown, Erika; Diamond, Kevin; Frenière, Normand; Grant, John; Pomerleau-Dalcourt, Natalie; Schella, Jason; Schreiner, L. John; Tantot, Laurent; Barajas, Eduardo Villareal; Bissonnette, Jean-Pierre

    2016-01-01

    A close partnership between the Canadian Partnership for Quality Radiotherapy (CPQR) and the Canadian Organization of Medical Physicist’s (COMP) Quality Assurance and Radiation Safety Advisory Committee (QARSAC) has resulted in the development of a suite of Technical Quality Control (TQC) Guidelines for radiation treatment equipment, that outline specific performance objectives and criteria that equipment should meet in order to assure an acceptable level of radiation treatment quality. The framework includes consolidation of existing guidelines and/or literature by expert reviewers, structured stages of public review, external field-testing and ratification by COMP. The adopted framework for the development and maintenance of the TQCs ensures the guidelines incorporate input from the medical physics community during development, measures the workload required to perform the QC tests outlined in each TQC, and remain relevant (i.e. “living documents”) through subsequent planned reviews and updates. This presentation will show the Multi-Leaf Linear Accelerator document as an example of how feedback and cross-national work to achieve a robust guidance document. During field-testing, each technology was tested at multiple centres in a variety of clinic environments. As part of the defined feedback, workload data was captured. This lead to average time associated with testing as defined in each TQC document. As a result, for a medium-sized centre comprising 6 linear accelerators and a comprehensive brachytherapy program, we evaluate the physics workload to 1.5 full-time equivalent physicist per year to complete all QC tests listed in this suite.

  15. Sci-Fri AM: Quality, Safety, and Professional Issues 01: CPQR Technical Quality Control Suite Development including Quality Control Workload Results

    Energy Technology Data Exchange (ETDEWEB)

    Malkoske, Kyle; Nielsen, Michelle; Brown, Erika; Diamond, Kevin; Frenière, Normand; Grant, John; Pomerleau-Dalcourt, Natalie; Schella, Jason; Schreiner, L. John; Tantot, Laurent; Barajas, Eduardo Villareal; Bissonnette, Jean-Pierre [Royal Victoria Hospital, Trillium Health Partners, CPQR, Juravinski Cancer Centre, CIUSSS MCQ - CHAUR, Cape Breton Health Care Complex, Centre d’oncologie Dr. Léon-Richard / Dr. Léon Richard Oncology Centre, QEII Health Sciences Centre, Cancer Centre of Southeastern Ontario, Hôpital Maisonneuve-Rosemont, Tom Baker Cancer Centre, Princess Margaret Cancer Centre (Canada)

    2016-08-15

    A close partnership between the Canadian Partnership for Quality Radiotherapy (CPQR) and the Canadian Organization of Medical Physicist’s (COMP) Quality Assurance and Radiation Safety Advisory Committee (QARSAC) has resulted in the development of a suite of Technical Quality Control (TQC) Guidelines for radiation treatment equipment, that outline specific performance objectives and criteria that equipment should meet in order to assure an acceptable level of radiation treatment quality. The framework includes consolidation of existing guidelines and/or literature by expert reviewers, structured stages of public review, external field-testing and ratification by COMP. The adopted framework for the development and maintenance of the TQCs ensures the guidelines incorporate input from the medical physics community during development, measures the workload required to perform the QC tests outlined in each TQC, and remain relevant (i.e. “living documents”) through subsequent planned reviews and updates. This presentation will show the Multi-Leaf Linear Accelerator document as an example of how feedback and cross-national work to achieve a robust guidance document. During field-testing, each technology was tested at multiple centres in a variety of clinic environments. As part of the defined feedback, workload data was captured. This lead to average time associated with testing as defined in each TQC document. As a result, for a medium-sized centre comprising 6 linear accelerators and a comprehensive brachytherapy program, we evaluate the physics workload to 1.5 full-time equivalent physicist per year to complete all QC tests listed in this suite.

  16. Quantifying Averted Disability-Adjusted Life Years as a Performance Indicator for Water Quality Interventions: A Review of Current Methodologies and Challenges

    Directory of Open Access Journals (Sweden)

    Darcy M. Anderson

    2018-06-01

    Full Text Available Sustainable access to safe drinking water protects against infectious disease and promotes overall health. Despite considerable progress toward increasing water access, safe water quality and reliable service delivery remain a challenge. Traditional financing strategies pay implementers based on inputs and activities, with minimal incentives for water quality monitoring and sustained service operation. Pay-for-performance offers an alternative financi